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Sample records for mi street address

  1. Report Period: EIA ID NUMBER: Instructions: (e.g., Street Address, Bldg, Floor, Suite)

    Gasoline and Diesel Fuel Update (EIA)

    Report Period: EIA ID NUMBER: Instructions: (e.g., Street Address, Bldg, Floor, Suite) Secure File Transfer option available at: (e.g., PO Box, RR) Electronic Transmission: The PC Electronic Data Reporting Option (PEDRO) is available. Zip Code: - If interested in software, call (202) 586-9659. Email form to: Fax form to: (202) 586-9772 - - Mail form to: Oil & Gas Survey - - U.S. Department of Energy Ben Franklin Station PO Box 279 Washington, DC 20044-0279 Questions? Call toll free:

  2. Address:

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Address: ~~. . ~L~ -'7(J'", v...* "' **.* *...~.;~ .*. .''''.-.:'. Morris, Alexander From: Sent: To: Subject: FOIA-Central@hq.doe.gov Friday, January 14, 2011 4:52 PM FOIA-Central DOE Headquarters FOIA Request Name~ke S. Mitchel~ Organization: Operating Engineers 370 2011 w. Yakima St. Pasco~ WA. 99301 Phone: 509-545-1811 FAX: 509-545-1812 Email: mmitchell@iuoe370.org Record Description: ~ertified Payroll records for layne Christensen drilling, who is a subcontractor for CHPRC at the

  3. DOE - Office of Legacy Management -- Adrian - MI 01

    Office of Legacy Management (LM)

    Adrian - MI 01 FUSRAP Considered Sites Adrian, MI Alternate Name(s): Bridgeport Brass Co. Special Metals Extrusion Plant Bridgeport Brass Company General Motors General Motors Company, Adrian MI.01-1 Location: 1450 East Beecher Street, Adrian, Michigan MI.01-3 Historical Operations: Performed uranium extrusion research and development and metal fabrication work for the AEC using uranium, thorium, and plutonium. MI.01-2 Eligibility Determination: Eligible MI.01-1 Radiological Survey(s):

  4. DOE Street Lighting Consortium Releases Results of Public Street...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Street Lighting Consortium Releases Results of Public Street and Area Lighting Inventory Survey DOE Street Lighting Consortium Releases Results of Public Street and Area Lighting ...

  5. Brighter Lights, Safer Streets

    Broader source: Energy.gov [DOE]

    Thanks to support from an Energy Department Recovery Act grant, Washington, DC streets are becoming brighter.

  6. Report from the Street

    Energy Savers [EERE]

    SHERMAN STREET, CAMBRIDGE, MA 02140 617.354.4502 LAMPARTNERS.COM BLOG.LAMPARTNERS.COM Report from the Street Glenn Heinmiller, FIALD, LC, LEED AP Principal, Lam Partners Chair,...

  7. DOE - Office of Legacy Management -- Revere Copper and Brass Co - MI 04

    Office of Legacy Management (LM)

    Revere Copper and Brass Co - MI 04 FUSRAP Considered Sites Site: REVERE COPPER AND BRASS CO. ( MI.04 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: Revere Copper and Brass MI.04-1 Location: 5851 West Jefferson Street , Detroit , Michigan MI.04-1 Evaluation Year: 1990 MI.04-2 Site Operations: Extrusion of tuballoy rods, myrnalloy rods and beryllium shapes in the 1940s. MI.04-3 MI.04-4 Site Disposition: Eliminated - Radiation levels below criteria

  8. Demonstration of LED Street Lighting

    SciTech Connect (OSTI)

    Kinzey, B. R.; Royer, M. P.; Hadjian, M.; Kauffman, R.

    2013-06-01

    GATEWAY program and Municipal Solid-State Street Lighting Consortium report on a demonstration of LED street lighting in Kansas City, MO.

  9. 701 Ninth Street, NW

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Street, NW Washington, DC 20068 202 872-3057 William M. Gausman Vice President, Asset Management January 8, 2007 Mr. Anthony J. Como SEA Document Manager U.S. Department of ...

  10. 200 N. Spring Street

    Office of Legacy Management (LM)

    Dipartment of Energy. ,' Washington,DC20585 ., .\ FEB 1 7 ' 19g5' ,The Honorable Richa,rd. Riordon .', 200 N. Spring Street 'Los Angeles, California ,90012 '~ Dear Mayor Riordon: " Secretary of Energy Hazel O'Leary'has announced a neb approach to openness ins- the Department of Energy (DOE) and its communications with the public. fin support of this initiative, we are pleased~ to forward the enclosed information related to the. former Shannon Luminous Metals site in your jurisdiction that

  11. GATEWAY Demonstrations: LED Street Lighting

    SciTech Connect (OSTI)

    Cook, Tyson; Shackelford, Jordan; Pang, Terrance Pang

    2008-12-01

    This report summarizes an assessment project conducted to study the performance of light emitting diode (LED) luminaires in a street lighting application in San Francisco, CA.

  12. Frequently Asked Questions About the Municipal Solid-State Street Lighting

    Office of Environmental Management (EM)

    Consortium | Department of Energy Frequently Asked Questions About the Municipal Solid-State Street Lighting Consortium Frequently Asked Questions About the Municipal Solid-State Street Lighting Consortium This page addresses many of the questions about the Municipal Solid-State Street Lighting Consortium. How does my organization become a member? How do members participate and where? How are demonstration sites selected? How is information on demonstration sites shared? How is the

  13. Municipal Consortium LED Street Lighting Workshop Presentations...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Boston, MA Municipal Consortium LED Street Lighting Workshop Presentations and ... U.S. Department of Energy Boston's LED Street Lighting Initiative Joanne Massaro, ...

  14. Cate Street Capital Inc | Open Energy Information

    Open Energy Info (EERE)

    Cate Street Capital Inc Jump to: navigation, search Name: Cate Street Capital, Inc. Place: Portsmouth, New Hampshire Zip: 3801 Sector: Renewable Energy Product: New Hampshire-based...

  15. Pecan Street Project Inc | Open Energy Information

    Open Energy Info (EERE)

    Project Inc Jump to: navigation, search Name: Pecan Street Project Inc Place: Austin, Texas Zip: 78759 Product: Austin-based smart grid, energy system developer. The Pecan Street...

  16. Complete Streets Resources | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Complete Streets Resources Complete Streets Resources While transportation efficiency policies are often implemented under local governments, national and state programs can play supportive roles in reducing vehicle miles traveled. Find complete streets resources below. National Complete Streets Coalition. Back to Transportation

  17. Adaptive Street Lighting Controls | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Information Resources » Webcasts » Adaptive Street Lighting Controls Adaptive Street Lighting Controls This two-part DOE Municipal Solid-State Street Lighting Consortium webinar focused on LED street lighting equipped with adaptive control components. In Part I, presenters Amy Olay of the City of San Jose, CA, and Kelly Cunningham of the California Lighting Technology Center at UC Davis discussed their experiences as early adopters of these smart street lighting systems. In Part II, presenters

  18. DOE Street Lighting Consortium Releases Results of Public Street and Area

    Office of Environmental Management (EM)

    Lighting Inventory Survey | Department of Energy Street Lighting Consortium Releases Results of Public Street and Area Lighting Inventory Survey DOE Street Lighting Consortium Releases Results of Public Street and Area Lighting Inventory Survey October 16, 2014 - 12:00pm Addthis DOE's Municipal Solid-State Street Lighting Consortium (MSSLC) has released the results of a voluntary web-based inventory survey of public street and area lighting across the U.S., conducted during the latter half

  19. 2013 Wall Street Perspective on SMRs | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Wall Street Perspective on SMRs 2013 Wall Street Perspective on SMRs Summary of results of a 2013 survey on Wall Street attitudes toward small modular reactors. PDF icon 2013 Wall Street Perspective on SMRs More Documents & Publications 2014 Wall Street Perspectives on SMRs - Report 2014 Wall Street Perspective on SMRs 2015 Wall Street Perspectives on SMRs Update

  20. LEDs for Street Lighting—Here Today

    SciTech Connect (OSTI)

    2013-11-29

    Fact sheet that provides a brief overview of the viability of LED street lighting in municipalities and highlights case studies of two cities—Los Angeles and Seattle—that have invested in LED street lighting.

  1. Smart Street Lights | GE Global Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    LightGrid Provides Real-Time Feedback From Street Lights Click to email this to a friend ... LightGrid Provides Real-Time Feedback From Street Lights You use a GPS to provide ...

  2. Municipal Consortium LED Street Lighting Workshop Presentations...

    Energy Savers [EERE]

    Los Angeles, CA Municipal Consortium LED Street Lighting Workshop Presentations and ... Lighting L.M. Seventynine: Who Is He and What Does He Have to Do with LED Street Lighting? ...

  3. Detroit Street Lighting Report | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Detroit Street Lighting Report Detroit Street Lighting Report PDF icon 2015_restoring-detroit.pdf More Documents & Publications LED Roadway Lighting OCTOBER 2015 POSTINGS Trial Demonstration of Area Lighting Retrofit

  4. Company Name: Preparer Name: Company Address: Preparer Title:

    Gasoline and Diesel Fuel Update (EIA)

    Company Name: Preparer Name: Company Address: Preparer Title: Company City: Preparer Company Name: Company State: Preparer Address: Company Zip Code: Preparer City: Preparer State: Parent Company Name: Preparer Zip Code: Parent Company Street Address: Preparer Phone #: Parent Company City: Preparer Fax #: Parent Company State: Preparer E-mail Address: Parent Company Zip Code: Supervisor Name: Supervisor Title: Supervisor Company Name: Supervisor Address: Supervisor City: Supervisor State:

  5. SSL Demonstration: Street Lighting, Kansas City, MO

    SciTech Connect (OSTI)

    2013-08-01

    GATEWAY program report brief summarizing an SSL street lighting demonstration at nine separate installations in Kansas City, MO.

  6. 2014 Wall Street Perspectives on SMRs - Report | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Perspectives on SMRs - Report 2014 Wall Street Perspectives on SMRs - Report Summary of the results of a 2014 survey of Wall Street attitudes toward small modular reactors. PDF icon View from Wall Street: Nuclear Energy and Small Modular Reactors More Documents & Publications 2013 Wall Street Perspective on SMRs 2014 Wall Street Perspective on SMRs 2015 Wall Street Perspectives on SMRs Update

  7. 2015 Wall Street Perspectives on SMRs Update | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Wall Street Perspectives on SMRs Update 2015 Wall Street Perspectives on SMRs Update Summary briefing on the results of a September 2015 survey of Wall Street attitudes toward SMRs. PDF icon 2015 Financial Survey: Nuclear Energy More Documents & Publications 2014 Wall Street Perspective on SMRs 2014 Wall Street Perspectives on SMRs - Report 2013 Wall Street Perspective on SMRs

  8. Restoring Detroit's Street Lighting System

    SciTech Connect (OSTI)

    Kinzey, Bruce R.

    2015-10-21

    The City of Detroit is undertaking a comprehensive restoration of its street lighting system that includes transitioning the existing high-pressure sodium (HPS) sources to light-emitting diode (LED). Detroit’s well-publicized financial troubles over the last several years have added many hurdles and constraints to this process. Strategies to overcome these issues have largely been successful, but have also brought some mixed results. This document provides an objective review of the circumstances surrounding the system restoration, the processes undertaken and decisions made, and the results so far.

  9. California Street Biomass Facility | Open Energy Information

    Open Energy Info (EERE)

    2006 Database Retrieved from "http:en.openei.orgwindex.php?titleCaliforniaStreetBiomassFacility&oldid397263" Feedback Contact needs updating Image needs updating...

  10. Municipal Consortium LED Street Lighting Workshop Presentations...

    Energy Savers [EERE]

    Dallas, TX Municipal Consortium LED Street Lighting Workshop Presentations and Materials-Dallas, TX This page provides links to the presentations given at the DOE Municipal ...

  11. Restoring Detroits Street Lighting System

    Energy Savers [EERE]

    once completed in 2016. Table ES.1. Annual savings a from Detroit street lighting transition Annual Energy Savings (kWh) Annual Electric Cost Savings () Annual...

  12. 2014 Wall Street Perspective on SMRs | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Perspective on SMRs 2014 Wall Street Perspective on SMRs Summary briefing on the results of a 2014 survey of Wall Street attitudes toward SMRs. PDF icon 2014 New Generation Financial Survey More Documents & Publications 2014 Wall Street Perspectives on SMRs - Report 2015 Wall Street Perspectives on SMRs Update 2013 Wall Street Perspective on SMRs

  13. Flooded First Street at Y-12 Plant | Y-12 National Security Complex

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Flooded First Street at ... Flooded First Street at Y-12 Plant Vehicles negotiate flooded First Street at Y-12 Plant

  14. Solar Resource Measurements in 1400 JR Lynch Street, Jackson...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Solar Resource Measurements in 1400 JR Lynch Street, Jackson, Mississippi Cooperative ... CRADA Number: CRD-07-254 CRADA Title: Solar Resource Measurements in 1400 JR Lynch Street, ...

  15. Portland Street Lighting Report (August 2015) | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    2015_gateway-msslc_portland.pdf More Documents & Publications OCTOBER 2015 POSTINGS Detroit Street Lighting Report Demonstration Assessment of Light Emitting Diode (LED) Street Lighting, Final Report

  16. Demonstration of LED Street Lighting in Kansas City, MO (Technical...

    Office of Scientific and Technical Information (OSTI)

    Report: Demonstration of LED Street Lighting in Kansas City, MO Citation Details In-Document Search Title: Demonstration of LED Street Lighting in Kansas City, MO Nine different ...

  17. Demonstration Assessment of Light-Emitting Diode (LED) Street...

    Office of Scientific and Technical Information (OSTI)

    Street Lighting Host Site: Lija Loop, Portland, Oregon Citation Details In-Document Search Title: Demonstration Assessment of Light-Emitting Diode (LED) Street Lighting Host Site: ...

  18. Member Case Studies: LED Street Lighting Programs in Algona ...

    Energy Savers [EERE]

    Member Case Studies: LED Street Lighting Programs in Algona (IA), Asheville (NC), and Boston (MA) Member Case Studies: LED Street Lighting Programs in Algona (IA), Asheville (NC), ...

  19. Demonstration Assessment of Light Emitting Diode (LED) Street...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Demonstration Assessment of Light Emitting Diode (LED) Street Lighting, Final Report Demonstration Assessment of Light Emitting Diode (LED) Street Lighting, Final Report This ...

  20. EECBG Success Story: Brighter Lights, Safer Streets | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Brighter Lights, Safer Streets EECBG Success Story: Brighter Lights, Safer Streets May 15, ... Photo courtesy of Michael Jaycocks EECBG Success Story: North Carolina Playing Fields ...

  1. US ENC MI Site Consumption

    U.S. Energy Information Administration (EIA) Indexed Site

    MI Site Consumption million Btu $0 $500 $1,000 $1,500 $2,000 $2,500 US ENC MI Expenditures dollars ALL ENERGY average per household (excl. transportation) 0 2,000 4,000 6,000 8,000 10,000 12,000 US ENC MI Site Consumption kilowatthours $0 $250 $500 $750 $1,000 $1,250 $1,500 US ENC MI Expenditures dollars ELECTRICITY ONLY average per household * Michigan households use 123 million Btu of energy per home, 38% more than the U.S. average. * High consumption, combined with low costs for heating fuels

  2. Remaining Barriers to LED Street Lighting

    Energy Savers [EERE]

    ownership, involving multiple decision-makers * Utilities own 60-70% of street lighting inventory in U.S. * Sometimes more than one utility present in a given metro area * Often...

  3. Municipal Solid-State Street Lighting Consortium

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Municipal Solid-State Street Lighting Consortium 2014 Building Technologies Office Peer Review Day Burners in Detroit, December 2013 Marc Ledbetter, Marc.Ledbetter@pnnl.gov Pacific Northwest National Laboratory Project Summary Timeline: Start date: April, 2010 Planned end date: FY19 Key Milestones 1. Detroit joining MSSLC and deciding to pursue an LED-based system, November, 2013 2. Model Controls Specification V2.0 released; April, 2014 3. Street Lighting Controls Demonstration Established,

  4. Portland Street Lighting Report (August 2015) | Department of Energy

    Energy Savers [EERE]

    Portland Street Lighting Report (August 2015) Portland Street Lighting Report (August 2015) PDF icon 2015_gateway-msslc_portland.pdf More Documents & Publications OCTOBER 2015 POSTINGS Detroit Street Lighting Report Demonstration Assessment of Light Emitting Diode (LED) Street Lighting, Final Report

  5. Pecan Street Grid Demonstration Program. Final technology performance

    Office of Scientific and Technical Information (OSTI)

    report (Technical Report) | SciTech Connect Pecan Street Grid Demonstration Program. Final technology performance report Citation Details In-Document Search Title: Pecan Street Grid Demonstration Program. Final technology performance report This document represents the final Regional Demonstration Project Technical Performance Report (TPR) for Pecan Street Inc.'s (Pecan Street) Smart Grid Demonstration Program, DE-OE-0000219. Pecan Street is a 501(c)(3) smart grid/clean energy research and

  6. Alternative Fuels Data Center: Natural Gas Street Sweepers Improve Air

    Alternative Fuels and Advanced Vehicles Data Center [Office of Energy Efficiency and Renewable Energy (EERE)]

    Quality in New York Natural Gas Street Sweepers Improve Air Quality in New York to someone by E-mail Share Alternative Fuels Data Center: Natural Gas Street Sweepers Improve Air Quality in New York on Facebook Tweet about Alternative Fuels Data Center: Natural Gas Street Sweepers Improve Air Quality in New York on Twitter Bookmark Alternative Fuels Data Center: Natural Gas Street Sweepers Improve Air Quality in New York on Google Bookmark Alternative Fuels Data Center: Natural Gas Street

  7. US ENC MI Site Consumption

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    on central air conditioning for cooling. 0% 20% 40% 60% 80% 100% US ENC MI OtherNone Propane Electricity Natural Gas MAIN HEATING FUEL USED COOLING EQUIPMENT USED DIVISION:...

  8. change_address_111609

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    CHANGE OF ADDRESS and EMERGENCY NOTIFICATION TO: HUMAN RESOURCES DATE: Z Social Security Print First Name Print Middle Name or Initial Print Last Name (Currently in Payroll...

  9. Text-Alternative Version: Evaluating LED Street Lighting Solutions

    Office of Energy Efficiency and Renewable Energy (EERE)

    Below is the text-alternative version of the Evaluating LED Street Lighting Solutions webcast, held July 20, 2010.

  10. Pittsburgh LED Street Lighting Research Project Performance Criteria

    Broader source: Energy.gov [DOE]

    A Pittsburgh LED Street Lighting Research Project document on Technical and Aesthetic Performance for Business District LED Lighting.

  11. DOE Publishes Report on Detroit's Street Lighting Conversion | Department

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of Energy Report on Detroit's Street Lighting Conversion DOE Publishes Report on Detroit's Street Lighting Conversion October 7, 2015 - 12:00pm Addthis The U.S. Department of Energy has released a new report on the comprehensive street lighting restoration currently being undertaken by the City of Detroit, which includes transitioning the existing high-pressure sodium (HPS) sources to LED. Entitled Restoring Detroit's Street Lighting System, the report provides an objective review of the

  12. Demonstration Assessment of Light Emitting Diode (LED) Street Lighting,

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Final Report | Department of Energy Demonstration Assessment of Light Emitting Diode (LED) Street Lighting, Final Report Demonstration Assessment of Light Emitting Diode (LED) Street Lighting, Final Report This report summarizes an LED street lighting assessment project conducted to study the applicability of LED luminaires in a street lighting application. PDF icon emerging_tech_report_led_streetlighting.pdf More Documents & Publications Effective White Light Options for Parking Area

  13. Using the Street and Parking Facility Lighting Retrofit Financial Analysis

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Tool | Department of Energy Using the Street and Parking Facility Lighting Retrofit Financial Analysis Tool Using the Street and Parking Facility Lighting Retrofit Financial Analysis Tool This August 22, 2013 webinar provided a guided walk-through of the Street and Parking Facility Lighting Retrofit Financial Analysis Tool. Developed by a partnership of the DOE Municipal Solid-State Street Lighting Consortium, the Clinton Climate Initiative/C40, and the DOE Federal Energy Management Program,

  14. Municipal Consortium LED Street Lighting Workshop Presentations and

    Energy Savers [EERE]

    Materials-Boston, MA | Department of Energy Boston, MA Municipal Consortium LED Street Lighting Workshop Presentations and Materials-Boston, MA This page provides links to the presentations given at the DOE Municipal Solid-State Street Lighting Consortium Workshop held in Boston August 2-3, 2012. Workshop Agenda DOE Municipal Solid-State Street Lighting Consortium James Brodrick, U.S. Department of Energy Boston's LED Street Lighting Initiative Joanne Massaro, Glenn Cooper, Matthew Mayrl,

  15. Real-time sub-<mi>>ngstrom...

    Office of Scientific and Technical Information (OSTI)

    Real-time sub-<mi>>ngstrom imaging of reversible and irreversible conformations in rhodium catalysts and graphene Kisielowski, Christian; Wang,...

  16. Notices Disabled, 1401 S. Clark Street, Suite

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    913 Federal Register / Vol. 78, No. 240 / Friday, December 13, 2013 / Notices Disabled, 1401 S. Clark Street, Suite 10800, Arlington, Virginia 22202-4149. FOR FURTHER INFORMATION CONTACT: Barry S. Lineback, Telephone: (703) 603-7740, Fax: (703) 603-0655, or email CMTEFedReg@AbilityOne.gov. SUPPLEMENTARY INFORMATION: Addition On 6/28/2013 (78 FR 38952-38953), the Committee for Purchase From People Who Are Blind or Severely Disabled published notice of proposed addition to the Procurement List.

  17. America Saves: Energizing Main Street Small Businesses

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    America Saves: Energizing Main Street Small Businesses Sara Stiltner, sstiltner@savingplaces.org National Trust for Historic Preservation 2015 Building Technologies Office Peer Review Demonstrate a community-based approach to small business and non-profit participation in utility energy retrofit programs and district-based sustainability initiatives. Project Summary Timeline: Start date: 10/1/2013 Planned end date: 9/30/2016 Key Milestones: 1. Data collection pilot identified; 7/2014 2. Field

  18. Southwestern Power Administration One West Third Street

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Power Administration One West Third Street Tulsa OK 74103-3502 918 595 6600 Fax 918 595 6656 www.swpa.gov An Agency of the United States Department of Energy Southwestern Power Administration Strategic Plan March 2013 Administrator's Message The Southwestern Power Administration powers the future, all day, every day, as we have for 70 years, through times of abundant water, and through times of drought; despite floods, ice storms, and tornadoes. We have consistently fulfilled our commitment to

  19. Notices Disabled, 1401 S. Clark Street, Suite

    Energy Savers [EERE]

    13 Federal Register / Vol. 78, No. 240 / Friday, December 13, 2013 / Notices Disabled, 1401 S. Clark Street, Suite 10800, Arlington, Virginia 22202-4149. FOR FURTHER INFORMATION CONTACT: Barry S. Lineback, Telephone: (703) 603-7740, Fax: (703) 603-0655, or email CMTEFedReg@AbilityOne.gov. SUPPLEMENTARY INFORMATION: Addition On 6/28/2013 (78 FR 38952-38953), the Committee for Purchase From People Who Are Blind or Severely Disabled published notice of proposed addition to the Procurement List.

  20. Mi GmbH | Open Energy Information

    Open Energy Info (EERE)

    Mi GmbH Jump to: navigation, search Name: Mi GmbH Place: Switzerland Zip: CH-6340 Sector: Solar Product: Baar-based manufacturer and distributor of fruit juices. The firm is also...

  1. miRNAs in brain development

    SciTech Connect (OSTI)

    Petri, Rebecca; Malmevik, Josephine; Fasching, Liana; Åkerblom, Malin; Jakobsson, Johan

    2014-02-01

    MicroRNAs (miRNAs) are small, non-coding RNAs that negatively regulate gene expression at the post-transcriptional level. In the brain, a large number of miRNAs are expressed and there is a growing body of evidence demonstrating that miRNAs are essential for brain development and neuronal function. Conditional knockout studies of the core components in the miRNA biogenesis pathway, such as Dicer and DGCR8, have demonstrated a crucial role for miRNAs during the development of the central nervous system. Furthermore, mice deleted for specific miRNAs and miRNA-clusters demonstrate diverse functional roles for different miRNAs during the development of different brain structures. miRNAs have been proposed to regulate cellular functions such as differentiation, proliferation and fate-determination of neural progenitors. In this review we summarise the findings from recent studies that highlight the importance of miRNAs in brain development with a focus on the mouse model. We also discuss the technical limitations of current miRNA studies that still limit our understanding of this family of non-coding RNAs and propose the use of novel and refined technologies that are needed in order to fully determine the impact of specific miRNAs in brain development. - Highlights: • miRNAs are essential for brain development and neuronal function. • KO of Dicer is embryonically lethal. • Conditional Dicer KO results in defective proliferation or increased apoptosis. • KO of individual miRNAs or miRNA families is necessary to determine function.

  2. One West Third Street Tulsa, Oklahoma

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Third Street Tulsa, Oklahoma 74103-3502 918-595-6600 Fax 918-595-6656 www.swpa.gov The UPDATE is published by and for customers, retirees, and employees of Southwestern Power Administration like: Katherine (K.C.) Thomas Director, Division of Information Technology (CIO) Tulsa, Oklahoma Special thanks to: Ron Beck Miya Boyken Ashley Butler Scott Carpenter Mike Deihl Ruben Garcia William Hiller David Kannady Jim McDonald Beth Nielsen Fritha Ohlson Tracey Stewart U P D AT E S O U T H W E S T E R N

  3. America Saves! Energizing Main Street Small Businesses

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    America Saves! Energizing Main Street Small Businesses 2014 Building Technologies Office Peer Review Mark Huppert / mhuppert@savingplaces.org Ric Cochrane / rcochrane@savingplaces.org National Trust for Historic Preservation Project Summary Timeline: Start date: 10/1/2013 Planned end date: 9/30/2016 Key Milestones 1. Collect building attribute and utility energy data for 1,000 sites (9/30/14) 2. Engage at least one utility in a demonstration of engagement and retrofit analysis (9/30/14) Budget:

  4. Considering LEDs for Street and Area Lighting | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Information Resources » Videos » Considering LEDs for Street and Area Lighting Considering LEDs for Street and Area Lighting View Jim Brodrick's keynote video from the September 2009 IES Street and Area Lighting Conference in Philadelphia. View the text-alternative version. Solid-State Lighting Home About the Solid-State Lighting Program Research & Development SSL Basics Using LEDs Information Resources Conferences & Meetings Presentations Publications Webcasts Videos Tools

  5. Municipal Consortium LED Street Lighting Workshop Presentations and

    Energy Savers [EERE]

    Materials-Los Angeles, CA | Department of Energy Los Angeles, CA Municipal Consortium LED Street Lighting Workshop Presentations and Materials-Los Angeles, CA This page provides links to the presentations given at the DOE Municipal Solid-State Street Lighting Consortium Workshop held in Los Angeles April 19-20, 2012. Presentations and Materials Workshop Agenda City of Los Angeles: Changing Our Glow for Efficiency Ed Ebrahimian, City of Los Angeles Bureau of Street Lighting L.M. Seventynine:

  6. Municipal Solid-State Street Lighting Consortium Kickoff Webcast |

    Energy Savers [EERE]

    Department of Energy Webcasts » Municipal Solid-State Street Lighting Consortium Kickoff Webcast Municipal Solid-State Street Lighting Consortium Kickoff Webcast This May 6, 2010 webcast served as the first official meeting of the new DOE Municipal Solid-State Street Lighting Consortium. Ed Smalley of Seattle City Light and Bruce Kinzey of Pacific Northwest National Laboratory discussed the Consortium's mission and goals, and provided an overview of its first steps, and opportunities to

  7. LED Street Lighting Conversion Workshop Presentations | Department of

    Energy Savers [EERE]

    Energy Research & Development » Technology Application R&D » Municipal Consortium » News & Events » LED Street Lighting Conversion Workshop Presentations LED Street Lighting Conversion Workshop Presentations This page provides links to the presentations given at the National League of Cities Mobile Workshop, LED Street Lighting Conversion: Saving Your Community Money, While Improving Public Safety, held November 13, 2013, in Seattle, WA. Presentations and Materials State of

  8. Financing Guidance for LED Street Lighting Programs | Department of Energy

    Office of Environmental Management (EM)

    Financing Guidance for LED Street Lighting Programs Financing Guidance for LED Street Lighting Programs photo of an urban roadway at night lined with LED streetlights. Financing an LED street lighting replacement program can present a hurdle for many system owners, even if the planned transition offers very favorable economics. Replacing the existing system requires a significant budget, particularly as the scope of the program increases. Cities such as Los Angeles and Seattle have invested many

  9. DOE - Office of Legacy Management -- Try Street Terminal - PA 14

    Office of Legacy Management (LM)

    Try Street Terminal - PA 14 FUSRAP Considered Sites Site: TRY STREET TERMINAL (PA.14 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Try Street Terminal , Pittsburgh , Pennsylvania PA.14-1 Evaluation Year: 1987 PA.14-1 Site Operations: Circa 1943 - facility used to store 20 plus drums of uranium slag. PA.14-1 Site Disposition: Eliminated - Potential for residual radioactive contamination considered remote PA.14-1 Radioactive

  10. Demonstration of LED Street Lighting in Kansas City, MO Kinzey...

    Office of Scientific and Technical Information (OSTI)

    Street Lighting in Kansas City, MO Kinzey, Bruce R.; Royer, Michael P.; Hadjian, M.; Kauffman, Rick LED streetlighting; field illuminance measurement LED streetlighting; field...

  11. SEAD Street Lighting Evaluation Tool | Open Energy Information

    Open Energy Info (EERE)

    Name: SEAD Street Lighting Evaluation Tool AgencyCompany Organization: SEAD Sector: Energy Focus Area: Energy Efficiency Resource Type: Softwaremodeling tools User Interface:...

  12. DOE - Office of Legacy Management -- Michigan Velsicol Chemical Corp - MI

    Office of Legacy Management (LM)

    03 Michigan Velsicol Chemical Corp - MI 03 FUSRAP Considered Sites Site: MICHIGAN [VELSICOL] CHEMICAL CORP. (MI.03 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: Velsicol Chemical Corp. MI.03-1 Location: St. Louis , Michigan MI.03-2 Evaluation Year: Circa 1987 MI.03-3 Site Operations: Rare earth processing facility. MI.03-2 Site Disposition: Eliminated - No Authority - NRC survey MI.03-3 Radioactive Materials Handled: Yes Primary Radioactive

  13. DOE - Office of Legacy Management -- Star Cutter Corp - MI 15

    Office of Legacy Management (LM)

    Star Cutter Corp - MI 15 FUSRAP Considered Sites Site: STAR CUTTER CORP. (MI.15) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Farmington , Michigan MI.15-1 Evaluation Year: 1991 MI.15-2 Site Operations: Performed a one time uranium slug drilling operation test in 1956. MI.15-3 MI.15-1 Site Disposition: Eliminated - Potential for contamination considered remote based on limited scope and quantity of materials handled MI.15-2 Radioactive

  14. CHP at Post Street in Downtown Seattle

    SciTech Connect (OSTI)

    Gent, Stan

    2012-04-12

    The Post Street project had four (4), 7.960 MW, Solar Taurus-70-10801S natural gas combustion turbines. Each turbine equipped with a 40,000 lb/hr heat recovery steam generator (HRSG). The dual-fuel HRSGs was capable of generating steam using gas turbine exhaust heat or surplus electric power. The generation capacity was nominally rated at 29.2 MW. The project as proposed had a fuel rate chargeable to power of 4,900 - 5,880 Btu/kWh dependent on time of year. The CHP plant, when operating at 29.2 MW, can recycle turbine exhaust into supply 145 kpph of steam to SSC per hour. The actual SSC steam loads will vary based on weather, building occupation, plus additions / reductions of customer load served. SSC produces up to 80 kpph of steam from a biomass boiler, which is currently base loaded all year.

  15. CONTRACTOR AND ADDRESS COEPPRACT FOR: TERM: COMMT.SSION OBLIGATION

    Office of Legacy Management (LM)

    CONTRACTOR AND ADDRESS COEPPRACT FOR: TERM: COMMT.SSION OBLIGATION PAYMENT TO m MADE BY: CONTRACT NO. AT(30-l)-1247 CONTRACT pl AMERICAN MACHINE Ah'D FOUNDRY COMP'N' Second Avenue and 56th Street Brooklyn, New York MA$HR\?No AND OTHER WORK AND SERVICES August o' 19% to December 31 9 0 'lyj! 512O,ox).OO Division of Disbursement, United States Treasury Department,' New York, New York. Subn-it invoices to: United States Atomic Energy Corrcni&ion, P. 0. %x 30, Ansonia Station New York 23, l!tw

  16. Municipal Consortium LED Street Lighting Workshop: April 19–20, Los Angeles, CA

    Broader source: Energy.gov [DOE]

    Workshop Location: The Sheraton Los Angeles Downtown Hotel, 711 Hope Street, Los Angeles, CA 90017City Partner: City of Los Angeles Bureau of Street LightingCost: $175

  17. DOE - Office of Legacy Management -- University of Michigan - MI 08

    Office of Legacy Management (LM)

    Michigan - MI 08 FUSRAP Considered Sites Site: UNIVERSITY OF MICHIGAN (MI.08) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Ann Arbor , Michigan MI.08-1 Evaluation Year: 1987 MI.08-2 Site Operations: Conducted research with a supersonic reflectroscope to detect flaws within a metal slug and developed methods for testing the adequacy of coatings which are applied to pieces of uranium metal. MI.08-1 MI.08-3 Site Disposition:

  18. DOE - Office of Legacy Management -- Wolverine Tube Division - MI 05

    Office of Legacy Management (LM)

    Wolverine Tube Division - MI 05 FUSRAP Considered Sites Site: Wolverine Tube Division (MI.05) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: Wolverine Tube Division of Calumet & Hecla Consolidated Copper Co. Star Tool Hermes Automotive Manufacturing Corporation MI.05-1 MI.05-2 Location: 1411 Central Avenue , Detroit , Michigan MI.05-3 Evaluation Year: 1990 MI.05-2 Site Operations: 1943 - Conducted research and development of methods for spinning

  19. DOE - Office of Legacy Management -- Carboloy Co - MI 12

    Office of Legacy Management (LM)

    Carboloy Co - MI 12 FUSRAP Considered Sites Site: Carboloy Co. (MI.12 ) Eliminated from further consideration under FUSRAP - AEC licensed facility Designated Name: Not Designated Alternate Name: General Electric MI.12-1 Location: 11177 E. Eight Mile Road , Detroit , Michigan MI.12-1 MI.12-2 Evaluation Year: 1987-1991 MI.12-3 MI.12-4 MI.12-6 Site Operations: Turned-down the outer diameter of uranium metal slugs and conducted pilot plant scale operations for hot pressing uranium dioxide pellets

  20. FirstEnergy (Potomac Edison)- Municipal and Street Lighting Program

    Broader source: Energy.gov [DOE]

    FirstEnergy (Potomac Edision) offers several incentives for non-residential and municipal customers to upgrade traffic signals, pedestrian signals, street lights to more efficient  fixtures. The...

  1. Using the Street and Parking Facility Lighting Retrofit Financial...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Developed by a partnership of the DOE Municipal Solid-State Street Lighting Consortium, the Clinton Climate InitiativeC40, and the DOE Federal Energy Management Program, the Excel...

  2. The Recovery Act is "Lighting Up" the streets of Philadelphia

    Broader source: Energy.gov [DOE]

    The Philadelphia Streets Department is converting 58,000 yellow and green traffic signals and will replace approximately 27,000 red LED lights that have come to the end of their useful life. The...

  3. Municipal Consortium LED Street Lighting Workshop Presentations and

    Energy Savers [EERE]

    Materials-Dallas, TX | Department of Energy Dallas, TX Municipal Consortium LED Street Lighting Workshop Presentations and Materials-Dallas, TX This page provides links to the presentations given at the DOE Municipal Solid-State Street Lighting Consortium Workshop held in Dallas March 15-16, 2012. Presentations and Materials Workshop Agenda ONCOR LED Streetlight Pilot & Technical Evaluation Update Michael Navarro, ONCOR Reading, Understanding, and Applying the LM-80 Standard Chad

  4. Secretary Moniz Applauds Detroit's LED Street Lighting Upgrades |

    Energy Savers [EERE]

    Department of Energy Secretary Moniz Applauds Detroit's LED Street Lighting Upgrades Secretary Moniz Applauds Detroit's LED Street Lighting Upgrades June 16, 2014 - 10:46am Addthis Secretary of Energy Ernest Moniz visited Detroit on May 22, 2014, to mark the city's progress installing energy-efficient LED streetlights in an update of its largely broken public lighting system, speaking at the Detroit Area Pre-College Engineering Program. Like so many cities across the country, Detroit is

  5. Webcast: Evaluating LED Street Lighting Solutions | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    In this July 20, 2010 webcast, Edward Smalley of Seattle City Light provided an update on DOE Municipal Solid-State Street Lighting Consortium activities. The webcast also presented perspectives from members who are involved with implementing LED street lighting evaluations, including Tod Rosinbum of the City of Portland, Oregon, John Walter of National Grid, and Amy Olay of the City of San Jose, California. View presentation slides Introduction (PDF 984 KB) Edward Smalley, DOE Municipal

  6. Webcast: Municipal Solid-State Street Lighting Consortium Retrofit

    Broader source: Energy.gov (indexed) [DOE]

    Financial Analysis Tool | Department of Energy This April 3, 2012 webcast presented information about the Retrofit Financial Analysis Tool developed by DOE"s Municipal Solid-State Street Lighting Consortium. Doug Elliott of Pacific Northwest National Laboratory provided a guided walk-through of what the tool can do and how to use it to evaluate costs and benefits associated with converting to LED street and roadway lighting. The webcast showed how city and other government agencies,

  7. New Rules Help Pocahontas Brighten Streets | Department of Energy

    Office of Environmental Management (EM)

    Rules Help Pocahontas Brighten Streets New Rules Help Pocahontas Brighten Streets October 21, 2010 - 10:00am Addthis The City of Pocahontas, Iowa swill replace sodium streetlights with LED fixtures. | File photo The City of Pocahontas, Iowa swill replace sodium streetlights with LED fixtures. | File photo Maya Payne Smart Former Writer for Energy Empowers, EERE What are the key facts? Pocahontas, Iowa was awarded a Recovery Act grant of more than $81,000. The city will replace 266 high-pressure

  8. Mr. Mark Finkelstein State Street,Associates'L..P. II

    Office of Legacy Management (LM)

    Mr. Mark Finkelstein State Street,Associates'L..P. II 210 Lake Street Ithaca, New York I4856 Dear Mr. Finkelstein: ', 'The Oak Ridge Institute forScience',and Education (ORISEj,has recently sent me the enclosed'radiological survey,conducted at the former Ithaca Gun Company forging building. : The radiationilevels measured during, the'survey were similar to the background'levels in the Ithaca 'area. A number of samples were taken for analysis, and all exhibited background ,concentrations of

  9. Brinkman Addresses JLab | Jefferson Lab

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Brinkman Addresses JLab Brinkman Addresses JLab Dr. William F. Brinkman, Director of the Department of Energy's Office of Science, addressed Jefferson Lab staff on the Office of Science perspective during his visit Monday. Dr. William F. Brinkman, Director of the Department of Energy's Office of Science, addressed Jefferson Lab staff on the Office of Science perspective during his visit Monday. "There is still a lot of interesting nuclear physics that we want to do and are enthusiastic

  10. DOE Municipal Solid-State Street Lighting Consortium | Department of Energy

    Energy Savers [EERE]

    Research & Development » Technology Application R&D » DOE Municipal Solid-State Street Lighting Consortium DOE Municipal Solid-State Street Lighting Consortium The DOE Municipal Solid-State Street Lighting Consortium shares technical information and experiences related to LED street and area lighting demonstrations and serves as an objective resource for evaluating new products on the market intended for those applications. Cities, power providers, and others who invest in street and

  11. DOE - Office of Legacy Management -- Oliver Corp - MI 11

    Office of Legacy Management (LM)

    Oliver Corp - MI 11 FUSRAP Considered Sites Site: OLIVER CORP. (MI.11 ) Eliminated from further consideration under FUSRAP - Referred to NRC Designated Name: Not Designated Alternate Name: Behnke Warehousing Incorporated MI.11-1 Location: 433 East Michigan Avenue , Battle Creek , Michigan MI.11-1 Evaluation Year: 1986 MI.11-4 Site Operations: Conducted production scale briquetting of green salt and magnesium blend under AEC license Nos. SNM-591, SUB-579, and C-3725. MI.11-1 MI.11-3 Site

  12. The NuMI Neutrino Beam

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Adamson, P.; Anderson, K.; Andrews, M.; Andrews, R.; Anghel, I.; Augustine, D.; Aurisano, A.; Avvakumov, S.; Ayres, D. S.; Baller, B.; et al

    2015-10-20

    Our paper describes the hardware and operations of the Neutrinos at the Main Injector (NuMI) beam at Fermilab. It elaborates on the design considerations for the beam as a whole and for individual elements. The most important part of our design details pertaining to individual components is described. Beam monitoring systems and procedures, including the tuning and alignment of the beam and NuMI long-term performance, are also discussed.

  13. Superfund Record of Decision (EPA Region 2): Love Canal (93rd Street School), Niagara County, City of Niagara Falls, NY. (Third remedial action), (amendment), May 1991. Final report

    SciTech Connect (OSTI)

    Not Available

    1991-05-15

    The Love Canal (93rd Street) site is an inactive hazardous waste site located in Niagara Falls, New York. The 19-acre 93rd Street School site, one of several operable units for the Love Canal Superfund site, is the focus of the Record of Decision (ROD). The fill material is reported to contain fly ash and BHC (a pesticide) waste. The ROD amends the 1988 ROD, and addresses final remediation of onsite contaminated soil through excavation and offsite disposal. The primary contaminants of concern affecting the soil are VOCs including toluene and xylenes; other organics including PAHs and pesticides; and metals including arsenic, chromium, and lead.

  14. DOE - Office of Legacy Management -- Westinghouse Naval Ordnance - MI 02

    Office of Legacy Management (LM)

    Naval Ordnance - MI 02 FUSRAP Considered Sites Site: WESTINGHOUSE NAVAL ORDNANCE (MI.02 ) Eliminated from further consideration under FUSRAP - Referred to DOD Designated Name: Not Designated Alternate Name: None Location: Detroit , Michigan MI.02-1 Evaluation Year: 1987 MI.02-2 Site Operations: Worked under contract with the Albuquerque Operations Office. No indication that radioactive material was involved under the contract. MI.02-2 Site Disposition: Eliminated - No indication radioactive

  15. DOE - Office of Legacy Management -- Detrex Corp - MI 10

    Office of Legacy Management (LM)

    Detrex Corp - MI 10 FUSRAP Considered Sites Site: Detrex Corp. (MI.10 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Detroit , Michigan MI.10-1 Evaluation Year: 1987 MI.10-2 Site Operations: Conducted experimental runs relative to pickling/degreasing of one handful of uranium turnings MI.10-1 Site Disposition: Eliminated - Potential for contamination considered remote due to small quantity of material handled - There is no

  16. Keynote Address | Department of Energy

    Energy Savers [EERE]

    Address Keynote Address An overview and update on Environmental Management given by Alice Williams, Associate Principal Deputy Assistant Secretary of the Office of Environmental Management. PDF icon Keynote Address More Documents & Publications U.S. Department of Energy Responses to Public Comments on the Draft Waste- Incidental-to-Reprocessing Evaluation for the West Valley Demonstration Project Concentrator Feed Makeup Tank and Melter Feed Hold Tank EIS-0337-SA-01: Supplement Analysis

  17. Keynote Address | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    40PM to 2:05PM PDT Pacific Ballroom Wednesday keynote address by Dan Arvizu, Director, National Renewable Energy Laboratory

  18. First Commercially Available Fuel Cell Electric Vehicles Hit the Street |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy First Commercially Available Fuel Cell Electric Vehicles Hit the Street First Commercially Available Fuel Cell Electric Vehicles Hit the Street December 10, 2014 - 12:25pm Addthis A fuel cell electric vehicle (FCEV) at a fueling station in California. New Energy Department reports signal rapid growth in America’s fuel cell and hydrogen industry as FCEVs are introduced to the market. | Energy Department photo A fuel cell electric vehicle (FCEV) at a fueling station

  19. C:\\PERFORM\\FORMS\\S1445.FRP

    Broader source: Energy.gov (indexed) [DOE]

    FIRST NAME MI STREET ADDRESS CITY STATE ZIP CODE WORK CLASSIFICATION WAGE RATE NAME OF PRIME CONTRACTOR NAME OF EMPLOYER SUPERVISOR'S NAME LAST NAME FIRST NAME MI ACTION CHECK...

  20. Keynote Address | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    10PM to 1:40PM PDT Pacific Ballroom Wednesday's keynote address by Dr. David Danielson, Assistant Secretary for Energy Efficiency and Renewable Energy, U.S. Department of Energy

  1. Demonstration Assessment of Light Emitting Diode (LED) Street Lighting, Phase III Continuation

    SciTech Connect (OSTI)

    Cook, Tyson; Shackelford, Jordan; Johnson, Megan; Pang, Terrance

    2008-11-01

    This report summarizes the third phase of an LED street lighting assessment project in Oakland, California, conducted to study the applicability of LED luminaires in a street lighting application.

  2. Text-Alternative Version: Keynote Video from Street and Area Lighting Conference

    Broader source: Energy.gov [DOE]

    Following is a text version of Jim Brodrick's keynote video from the recent Street and Area Lighting Conference.

  3. About the DOE Municipal Solid-State Street Lighting Consortium | Department

    Energy Savers [EERE]

    of Energy D » Municipal Consortium » About the DOE Municipal Solid-State Street Lighting Consortium About the DOE Municipal Solid-State Street Lighting Consortium Numerous cities and organizations around the nation are announcing plans to conduct large scale retrofits/comparisons of LED street and area lighting products with their conventional street lights. The relative newness of LED lighting raises a number of concerns: A significant and unnecessary duplication of effort is likely if

  4. Member Case Studies: LED Street Lighting Programs in Algona (IA), Asheville

    Energy Savers [EERE]

    (NC), and Boston (MA) | Department of Energy Member Case Studies: LED Street Lighting Programs in Algona (IA), Asheville (NC), and Boston (MA) Member Case Studies: LED Street Lighting Programs in Algona (IA), Asheville (NC), and Boston (MA) This May 8, 2013 webcast featured presentations from DOE Municipal Solid-State Street Lighting Consortium member cities about their experiences with LED street lighting. Presenters John Bilsten of Algona (IA) Municipal Utilities, Maggie Ullman of the City

  5. Street Legal Named SBA HUBZone Business of the Year | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Street Legal Named SBA HUBZone Business of the Year Street Legal Named SBA HUBZone Business of the Year November 3, 2014 - 3:06pm Addthis On Sept. 25, Street Legal Industries, Inc. was recognized as the U. S. Small Business Administration (SBA) 2014 Tennessee HUBZone Small Business of the Year. Street Legal Industries Inc. is a Woman-Owned, SBA HUBZone-certified, small business founded in 1994. The company provides professional infrastructure support services to federal and commercial entities.

  6. 2013 Director's New Year Address

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    2013 Director's New Year Address 2013 Director's New Year Address Print Looking Forward and Celebrating 20 Years in 2013 falocne We recently sat down with ALS Director Roger Falcone to talk about what 2013 has in store for the ALS. An immediate answer is - a celebration - as the ALS marks its 20th year of operation. We'll spend some time this year looking back at what we've accomplished over the past couple of decades and forward to how we'll continue to contribute to the future of scientific

  7. “Nodal Gap” induced by the incommensurate diagonal spin density modulation in underdoped high- <mi>Tmi>c> superconductors

    SciTech Connect (OSTI)

    Zhou, Tao; Gao, Yi; Zhu, Jian -Xin

    2015-03-07

    Recently it was revealed that the whole Fermi surface is fully gapped for several families of underdoped cuprates. The existence of the finite energy gap along the <mi>d>-wave nodal lines (nodal gap) contrasts the common understanding of the <mi>d>-wave pairing symmetry, which challenges the present theories for the high-<mi>Tmi><mi>c>superconductors. Here we propose that the incommensurate diagonal spin-density-wave order can account for the above experimental observation. The Fermi surface and the local density of states are also studied. Our results are in good agreement with many important experiments in high-<mi>Tmi><mi>c>superconductors.

  8. State of the Lab Address

    ScienceCinema (OSTI)

    King, Alex

    2013-03-01

    In his third-annual State of the Lab address, Ames Laboratory Director Alex King called the past year one of "quiet but strong progress" and called for Ames Laboratory to continue to build on its strengths while responding to changing expectations for energy research.

  9. The Honorable Robert E. Williams 44 W. Washington Street

    Office of Legacy Management (LM)

    SEC ; : ' ,-<- I ;;;s The Honorable Robert E. Williams 44 W. Washington Street Shelbyville, Indiana 46176 Dear Mayor Williams: Secretary of Energy Hazel O'Leary has announced a new approach to openness in the Department of Energy (DOE) and its communications with the public. In support of this initiative, we are pleased to forward the enclosed information related to the former General Electric Co. site in your jurisdiction that performed work for DOE or its predecessor agencies. This

  10. Addressing Deferred Maintenance, Infrastructure Costs, and Excess...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Addressing Deferred Maintenance, Infrastructure Costs, and Excess Facilities at Portsmouth and Paducah Addressing Deferred Maintenance, Infrastructure Costs, and Excess Facilities ...

  11. Energy Department Assistant Secretary Patricia Hoffman Addresses...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Patricia Hoffman Addresses 2011 FERC Reliability Technical Conference Energy Department Assistant Secretary Patricia Hoffman Addresses 2011 FERC Reliability Technical Conference ...

  12. Hydraulic Capacity of an ADA Compliant Street Drain Grate

    SciTech Connect (OSTI)

    Lottes, Steven A.; Bojanowski, Cezary

    2015-09-01

    Resurfacing of urban roads with concurrent repairs and replacement of sections of curb and sidewalk may require pedestrian ramps that are compliant with the American Disabilities Act (ADA), and when street drains are in close proximity to the walkway, ADA compliant street grates may also be required. The Minnesota Department of Transportation ADA Operations Unit identified a foundry with an available grate that meets ADA requirements. Argonne National Laboratorys Transportation Research and Analysis Computing Center used full scale three dimensional computational fluid dynamics to determine the performance of the ADA compliant grate and compared it to that of a standard vane grate. Analysis of a parametric set of cases was carried out, including variation in longitudinal, gutter, and cross street slopes and the water spread from the curb. The performance of the grates was characterized by the fraction of the total volume flow approaching the grate from the upstream that was captured by the grate and diverted into the catch basin. The fraction of the total flow entering over the grate from the side and the fraction of flow directly over a grate diverted into the catch basin were also quantities of interest that aid in understanding the differences in performance of the grates. The ADA compliant grate performance lagged that of the vane grate, increasingly so as upstream Reynolds number increased. The major factor leading to the performance difference between the two grates was the fraction of flow directly over the grates that is captured by the grates.

  13. DOE Zero Energy Ready Home Case Study 2013: StreetScape Development, LLC, Libertyville, IL, Custom, School Street Homes

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    StreetScape Development, LLC Libertyville, IL BUILDING TECHNOLOGIES OFFICE The U.S. Department of Energy invites home builders across the country to meet the extraordinary levels of excellence and quality specified in DOE's Zero Energy Ready Home program (formerly known as Challenge Home). Every DOE Zero Energy Ready Home starts with ENERGY STAR for Homes Version 3 for an energy-efficient home built on a solid foundation of building science research. Advanced technologies are designed in to give

  14. DOE - Office of Legacy Management -- Dow Chemical Co - Midland - MI 06

    Office of Legacy Management (LM)

    Midland - MI 06 FUSRAP Considered Sites Site: Dow Chemical Co. - Midland (MI.06 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Midland , Michigan MI.06-1 Evaluation Year: Circa 1987 MI.06-2 Site Operations: Conducted development work for production of magnesium-thorium alloys. MI.06-1 Site Disposition: Eliminated - AEC licensed site MI.06-1 MI.06-2 Radioactive Materials Handled: Yes Primary Radioactive Materials Handled:

  15. Addressing failures in exascale computing

    SciTech Connect (OSTI)

    Snir, Marc; Wisniewski, Robert W.; Abraham, Jacob A.; Adve, Sarita; Bagchi, Saurabh; Balaji, Pavan; Belak, Jim; Bose, Pradip; Cappello, Franck; Carlson, William; Chien, Andrew A.; Coteus, Paul; Debardeleben, Nathan A.; Diniz, Pedro; Engelmann, Christian; Erez, Mattan; Saverio, Fazzari; Geist, Al; Gupta, Rinku; Johnson, Fred; Krishnamoorthy, Sriram; Leyffer, Sven; Liberty, Dean; Mitra, Subhasish; Munson, Todd; Schreiber, Robert; Stearly, Jon; Van Hensbergen, Eric

    2014-05-01

    We present here a report produced by a workshop on Addressing Failures in Exascale Computing held in Park City, Utah, August 411, 2012. The charter of this workshop was to establish a common taxonomy about resilience across all the levels in a computing system; discuss existing knowledge on resilience across the various hardware and software layers of an exascale system; and build on those results, examining potential solutions from both a hardware and software perspective and focusing on a combined approach. The workshop brought together participants with expertise in applications, system software, and hardware; they came from industry, government, and academia; and their interests ranged from theory to implementation. The combination allowed broad and comprehensive discussions and led to this document, which summarizes and builds on those discussions.

  16. The Recovery Act is "Lighting Up" the streets of Philadelphia

    ScienceCinema (OSTI)

    Nutter, Michael; Gajewski, Katherine; Russell, Toby; Williams, Doug; Best, DeLain;

    2013-05-29

    The Philadelphia Streets Department is converting 58,000 yellow and green traffic signals and will replace approximately 27,000 red LED lights that have come to the end of their useful life. The project will use approximately $3 million in EECBG funds, matched with $3 million in PECO funding, and will save the city approximately $1 million in electric costs each year. For more information on Recovery Act projects funded by the Department of Energy in Pennsylvania: http://www.energy.gov/recovery/pa.htm

  17. The Recovery Act is "Lighting Up" the streets of Philadelphia

    SciTech Connect (OSTI)

    Nutter, Michael; Gajewski, Katherine; Russell, Toby; Williams, Doug; Best, DeLain;

    2010-01-01

    The Philadelphia Streets Department is converting 58,000 yellow and green traffic signals and will replace approximately 27,000 red LED lights that have come to the end of their useful life. The project will use approximately $3 million in EECBG funds, matched with $3 million in PECO funding, and will save the city approximately $1 million in electric costs each year. For more information on Recovery Act projects funded by the Department of Energy in Pennsylvania: http://www.energy.gov/recovery/pa.htm

  18. A LIMITED LIABILITY PARTNERSHIP 1050 Thomas Jefferson Street, NW

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    A LIMITED LIABILITY PARTNERSHIP 1050 Thomas Jefferson Street, NW Seventh Floor Washington, DC 20007 (202) 298-1800 Phone (202) 338-2416 Fax MEMORANDUM TO: DOE Office of General Counsel FROM: Doug Smith DATE: August 29, 2013 RE: Record of Communication Concerning Ceiling Fan and Ceiling Fan Light Kit Framework Document-Docket No. EERE-2012-BT-STD-0045 This memo provides an overview of communications made to DOE staff on the subject of possible changes to standards and test procedures for ceiling

  19. The Honorable Roy Bernadi 233 East Washington Street

    Office of Legacy Management (LM)

    ~ DC 20585 : DEC.'0 'i 1994 The Honorable Roy Bernadi 233 East Washington Street Syracuse, New York 13202, _ Dear,.Mayor Bernadj: -' Secretary of Energy HaieT O'Leary has announced a new approach.to openness in the Department,of Energy (DOE).and its coaununications with the public. In ., support.of 'this initiative, we are pleased to forward the e~nclosed information '. related to the Syracuse University'site, in your jurisdiction th,at performed work for DOE or its predecessor agencies..

  20. The Honorable Sandra Freedman 306 E. Jackson Street

    Office of Legacy Management (LM)

    N()\J (-j 3 ;;54 The Honorable Sandra Freedman 306 E. Jackson Street Tampa, Florida 33602 Dear Mayor Freedman: Secretary of Energy Hazel O'Leary has announced a new approach to openness in the Department of Energy (DOE) and its communications with the pu6lic. In support of this initiative, we are pleased to forward the enclosed information related to the former Gardinier, Inc. site in your jurisdiction that performed work for DOE's predecessor agencies. This information is provided for your

  1. Symbiosis: Addressing Biomass Production Challenges and Climate...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Symbiosis: Addressing Biomass Production Challenges and Climate Change Symbiosis: Addressing Biomass Production Challenges and Climate Change This presentation was the opening ...

  2. EPA -- Addressing Children's Health through Reviews Conducted...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Addressing Children's Health through Reviews Conducted Pursuant to the National Environmental Policy Act and Section 309 of the Clean Air Act EPA -- Addressing Children's Health ...

  3. Keynote Address: Update on Environmental Management | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Address: Update on Environmental Management Keynote Address: Update on Environmental Management Keynote presentation made by David G. Huizenga for the NTSF annual meeting held from...

  4. DOE - Office of Legacy Management -- General Motors Co - Flint - MI 07

    Office of Legacy Management (LM)

    Motors Co - Flint - MI 07 FUSRAP Considered Sites Site: GENERAL MOTORS CO. (MI.07 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: A.C. Spark Plug Dort Highway Plant MI.07-1 MI.07-2 Location: Flint , Michigan MI.07-1 Evaluation Year: 1987 MI.07-3 Site Operations: Processed thorium oxide, uranium oxide, and beryllium oxide into crucibles for the Chicago Area. MI.07-3 MI.07-4 MI.07-5 Site Disposition: Eliminated - Potential for contamination

  5. Demonstration Assessment of Light-Emitting Diode (LED) Street Lighting Host

    Office of Scientific and Technical Information (OSTI)

    Site: Lija Loop, Portland, Oregon (Technical Report) | SciTech Connect Street Lighting Host Site: Lija Loop, Portland, Oregon Citation Details In-Document Search Title: Demonstration Assessment of Light-Emitting Diode (LED) Street Lighting Host Site: Lija Loop, Portland, Oregon This report describes the process and results of a demonstration of solid-state lighting (SSL) technology in a residential street lighting application, under the U.S. Department of Energy GATEWAY Solid-State Lighting

  6. Demonstration of LED Street Lighting in Kansas City, MO (Technical Report)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    | SciTech Connect Demonstration of LED Street Lighting in Kansas City, MO Citation Details In-Document Search Title: Demonstration of LED Street Lighting in Kansas City, MO Nine different streetlighting products were installed on various streets in Kansas City, Missouri during February, 2011, to evaluate their performance relative to the incumbent high-pressure sodium (HPS) lighting. The applications investigated included 100 W, 150 W, 250 W, and 400 W HPS installations. Initial measurements

  7. DOE - Office of Legacy Management -- Utica Street Warehouse - NY 0-23

    Office of Legacy Management (LM)

    Street Warehouse - NY 0-23 FUSRAP Considered Sites Site: UTICA STREET WAREHOUSE (NY.0-23) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: 240 West Utica Street , Buffalo , New York NY.0-23-2 Evaluation Year: 1987 NY.0-23-1 Site Operations: Stored and rebarrelled uranium process residues from operations at Linde. NY.0-23-3 Site Disposition: Eliminated - Original building demolished. Current land use - Parking facility. Potential for

  8. Name Name Address Place Zip Category Sector Telephone number...

    Open Energy Info (EERE)

    Hydro Marine and Hydrokinetic http acep uaf edu facilities tanana river hydrokinetic test site aspx Alden Research Laboratory Inc Alden Research Laboratory Inc Shrewsbury Street...

  9. The Office of Minority Economic Impact (MI) was established in...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Minority Economic Impact (MI) was established in Fiscal Year 1979 pursuant to Section 641 ... PART 3 - - MINORITY ECONOMIC IMPACT SEC. 641. MINORITY ECONOMIC IMPACT. "(a) Establishment ...

  10. ,"Detroit, MI Natural Gas Pipeline Imports From Canada (MMcf...

    U.S. Energy Information Administration (EIA) Indexed Site

    ,"Worksheet Name","Description"," Of Series","Frequency","Latest Data for" ,"Data 1","Detroit, MI Natural Gas Pipeline Imports From Canada (MMcf)",1,"Annual",2014 ,"Release...

  11. MINOS Experiment and NuMI Beam Home Page

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NuMI-MINOS Neutrino Logo NuMI Beamline and MINOS Experiment Neutrino Logo The MINOS Experiment and NuMI Beamline Fermilab Logo MINOS Experiment Links ◊ MINOS for the Public ◊ Scientific Results ◊ MINOS at Work ◊ NuMI at Work ◊ MINOS+ Experiment Fermilab Neutrino Links ◊ Neutrino FAQ ◊ MINOS Underground Areas at Fermilab ◊ PPD Intensity Frontier Dept Back to - - - ◊ Fermilab at Work ◊ Fermilab Home the MINOS Far Detector in the Soudan Mine MINOS collaborators assembling the

  12. Text-Alternative Version: MSSLC Member Case Studies- LED Street Lighting Programs Webinar

    Broader source: Energy.gov [DOE]

    Below is the text-alternative version of the "MSSLC Member Case Studies - LED Street Lighting Programs" webcast, held May 8, 2013.

  13. Text-Alternative Version: Using the Street and Parking Facility Lighting Retrofit Financial Analysis Tool

    Broader source: Energy.gov [DOE]

    Below is the text-alternative version of the "Using the Street and Parking Facility Lighting Retrofit Financial Analysis Tool" webcast, held August 22, 2013.

  14. Text-Alternative Version: Municipal Solid-State Street Lighting Consortium Kickoff

    Broader source: Energy.gov [DOE]

    Below is the text-alternative version of the Municipal Solid-State Street Lighting Consortium Kickoff webcast, held May 6, 2010.

  15. Text-Alternative Version: Municipal Solid-State Street Lighting Consortium Retrofit Financial Analysis Tool Webcast

    Broader source: Energy.gov [DOE]

    Below is the text-alternative version of the "Municipal Solid-State Street Lighting Consortium Retrofit Financial Analysis Tool" webcast, held April 3, 2012.

  16. Secretary Chu Op-Ed on Small Modular Reactors in the Wall Street Journal |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Small Modular Reactors in the Wall Street Journal Secretary Chu Op-Ed on Small Modular Reactors in the Wall Street Journal March 23, 2010 - 12:00am Addthis Washington, D.C. - Today, the Wall Street Journal published an op-ed by U.S. Secretary of Energy Steven Chu on small modular reactors. The op-ed can be viewed on the Wall Street Journal. The text of the op-ed is below: America's New Nuclear Option Small modular reactors will expand the ways we use atomic power. By

  17. Secretary Chu's Op-Ed on Small Modular Reactors in the Wall Street Journal

    Broader source: Energy.gov [DOE]

    The Wall Street Journal published an op-ed by U.S. Secretary of Energy Steven Chu on small modular reactors.

  18. Address conversion unit for multiprocessor system

    SciTech Connect (OSTI)

    Fava, T.F.; Lary, R.F.; Blackledge, R.

    1987-03-03

    An address conversion unit is described for use in one processor in a multi-processor data processing system including a common memory, the processors and common memory being interconnected by a common bus including means for transferring address signals defining a common address space. The processor includes private bus means including means for transferring signals including address signals defining a private address space. A processor unit means is connected to the private bus means and includes means for transmitting and receiving signals including address signals over the private bus means for engaging in data transfers thereover. The address conversion unit is connected to the private bus means and common bus means for receiving address signals over the private bus means from the processor unit means in the private address space. The unit comprises: A. pointer storage means for storing a pointer identifying a portion of the common bus memory space; B. pointer generation means connected to receive a common bus address and for generating a pointer in response thereto for storage in the pointer storage means; and C. common bus address generation means connected to the private bus and the pointer storage means for receiving an address from the processor unit means and for generating a common bus address in response thereto. The common bus address is used to initiate transfers between the processor unit means and the common memory over the common bus.

  19. Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells

    SciTech Connect (OSTI)

    Vrba, Lukas; Jensen, Taylor J.; Garbe, James C.; Heimark, Ronald L.; Cress, Anne E.; Dickinson, Sally; Stampfer, Martha R.; Futscher, Bernard W.

    2009-12-23

    BACKGROUND: The microRNA-200 family participates in the maintenance of an epithelial phenotype and loss of its expression can result in epithelial to mesenchymal transition (EMT). Furthermore, the loss of expression of miR-200 family members is linked to an aggressive cancer phenotype. Regulation of the miR-200 family expression in normal and cancer cells is not fully understood. METHODOLOGY/ PRINCIPAL FINDINGS: Epigenetic mechanisms participate in the control of miR-200c and miR-141 expression in both normal and cancer cells. A CpG island near the predicted mir-200c/mir-141 transcription start site shows a striking correlation between miR-200c and miR-141 expression and DNA methylation in both normal and cancer cells, as determined by MassARRAY technology. The CpG island is unmethylated in human miR-200/miR-141 expressing epithelial cells and in miR-200c/miR-141 positive tumor cells. The CpG island is heavily methylated in human miR-200c/miR-141 negative fibroblasts and miR-200c/miR-141 negative tumor cells. Mouse cells show a similar inverse correlation between DNA methylation and miR-200c expression. Enrichment of permissive histone modifications, H3 acetylation and H3K4 trimethylation, is seen in normal miR-200c/miR-141-positive epithelial cells, as determined by chromatin immunoprecipitation coupled to real-time PCR. In contrast, repressive H3K9 dimethylation marks are present in normal miR-200c/miR-141-negative fibroblasts and miR-200c/miR-141 negative cancer cells and the permissive histone modifications are absent. The epigenetic modifier drug, 5-aza-2'-deoxycytidine, reactivates miR-200c/miR-141 expression showing that epigenetic mechanisms play a functional role in their transcriptional control. CONCLUSIONS/ SIGNIFICANCE: We report that DNA methylation plays a role in the normal cell type-specific expression of miR-200c and miR-141 and this role appears evolutionarily conserved, since similar results were obtained in mouse. Aberrant DNA methylation of the miR-200c/141 CpG island is closely linked to their inappropriate silencing in cancer cells. Since the miR-200c cluster plays a significant role in EMT, our results suggest an important role for DNA methylation in the control of phenotypic conversions in normal cells.

  20. Keynote Address: Future Vision | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Future Vision Keynote Address: Future Vision May 20, 2014 1:00PM to 1:30PM PDT Pacific Ballroom Tuesday's keynote address by Raffi Garabedian, Chief Technology Officer, First Solar

  1. Superfund record of decision amendment (EPA Region 2): Hooker (102nd Street Landfill), Niagara Falls, NY, June 9, 1995

    SciTech Connect (OSTI)

    1995-08-01

    This decision document presents the selected modification to the original remedial action (PB91-921417) for the 102nd Street Landfill Site (the `Site`), located in Niagara Falls, New York. The modification to the selected remedy addresses the river sediments within the shallow embayment of the Niagara River adjacent to the Site. The major components of the modification to the selected remedy include: dredging the Niagara River sediments to the `clean line` with respect to Site-related contamination. These sediments, after dewatering, will NOT be incinerated, but will be consolidated on the landfill. Any NAPL found within these sediments will be extracted, and will be incinerated at an off-site facility.

  2. miR-92a family and their target genes in tumorigenesis and metastasis

    SciTech Connect (OSTI)

    Li, Molin; Guan, Xingfang; Sun, Yuqiang; Mi, Jun; Shu, Xiaohong; Liu, Fang; Li, Chuangang

    2014-04-15

    The miR-92a family, including miR-25, miR-92a-1, miR-92a-2 and miR-363, arises from three different paralog clusters miR-17-92, miR-106a-363, and miR-106b-25 that are highly conservative in the process of evolution, and it was thought as a group of microRNAs (miRNAs) correlated with endothelial cells. Aberrant expression of miR-92a family was detected in multiple cancers, and the disturbance of miR-92a family was related with tumorigenesis and tumor development. In this review, the progress on the relationship between miR-92a family and their target genes and malignant tumors will be summarized. - Highlights: Aberrant expression of miR-92a, miR-25 and miR-363 can be observed in many kinds of malignant tumors. The expression of miR-92a family is regulated by LOH, epigenetic alteration, transcriptional factors such as SP1, MYC, E2F, wild-type p53 etc. Roles of miR-92a family in tumorigenesis and development: promoting cell proliferation, invasion and metastasis, inhibiting cell apoptosis.

  3. Demonstration of LED Street Lighting in Kansas City, MO

    SciTech Connect (OSTI)

    Kinzey, Bruce R.; Royer, Michael P.; Hadjian, M.; Kauffman, Rick

    2013-06-10

    Nine different streetlighting products were installed on various streets in Kansas City, Missouri during February, 2011, to evaluate their performance relative to the incumbent high-pressure sodium (HPS) lighting. The applications investigated included 100 W, 150 W, 250 W, and 400 W HPS installations. Initial measurements and comparisons included power, illuminance, and luminance; sample illuminance readings have continued at each of the nine locations at roughly 1,000-hour operating intervals since then. All of the LED products consumed less power than their HPS counterparts—with a mean difference of 39% and a range of 31% to 51%—but they also emitted 31% fewer lumens, on average. The net result is just a 15% increase in mean efficacy. Applying the city’s stringent light loss factors to the initial measured data meant that five of the LED products (and two of the HPS luminaires) were predicted to eventually fail to meet the specified mean illuminance over their lifetimes; however, the specified light loss levels are not expected to be reached by the LED products until some distant future date (between 12 and 30 years after installation according to manufacturer specification sheet estimates). The practical value of designing streetlighting systems to meet illumination requirements more than 15 years in the future is questioned. Numerous sources of variation in field measurements are noted throughout the report, particularly seasonal influences such as ambient temperature and foliage that are evident in the time-series illuminance data.

  4. DOE Zero Energy Ready Home Case Study: M Street Homes, Houston, TX |

    Energy Savers [EERE]

    Department of Energy M Street Homes, Houston, TX DOE Zero Energy Ready Home Case Study: M Street Homes, Houston, TX DOE Zero Energy Ready Home Case Study: M Street Homes, Houston, TX Case study of a DOE Zero Energy Ready home in Houston, TX, that achieves a HERS 45 without PV or HERS 32 with 1.2 kW PV. The three-story, 4,507-ft2 custom home is powered by a unique tri-generation system that supplies all of the home's electricity, heating, and cooling on site. The tri-generator is powered by a

  5. Using QECBs for Street Lighting Upgrades: Lighting the Way to Lower Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Bills in San Diego | Department of Energy QECBs for Street Lighting Upgrades: Lighting the Way to Lower Energy Bills in San Diego Using QECBs for Street Lighting Upgrades: Lighting the Way to Lower Energy Bills in San Diego Summarizes how the City of San Diego leveraged $13.1 million in qualified energy conservation bonds to increase the size of a street lighting upgrade project. Author: Lawrence Berkeley National Laboratory PDF icon Lighting the Way to Lower Energy Bills in San Diego More

  6. Detroit, MI Natural Gas Pipeline Imports From Canada (Million...

    U.S. Energy Information Administration (EIA) Indexed Site

    data. Release Date: 09302015 Next Release Date: 10302015 Referring Pages: U.S. Natural Gas Pipeline Imports by Point of Entry Detroit, MI Natural Gas Imports by Pipeline from...

  7. Detroit, MI Natural Gas Pipeline Imports From Canada (Dollars...

    U.S. Energy Information Administration (EIA) Indexed Site

    Date: 09302015 Next Release Date: 10302015 Referring Pages: U.S. Price of Natural Gas Pipeline Imports by Point of Entry Detroit, MI Natural Gas Imports by Pipeline from...

  8. DOE - Office of Legacy Management -- Baker-Perkins Co - MI 13

    Office of Legacy Management (LM)

    Baker-Perkins Co - MI 13 FUSRAP Considered Sites Site: Baker-Perkins Co (MI 13) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Saginaw , Michigan MI.13-1 Evaluation Year: 1991 MI.13-1 MI.13-2 Site Operations: Small scale oxide mixing demonstrations and testing in May, 1956. MI.13-2 Site Disposition: Eliminated - Potential for contamination remote based on limited scope of activities at the site MI.13-3 Radioactive Materials Handled: Yes

  9. Research Projects Addressing Technical Challenges to Environmentally

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Acceptable Shale Gas Development Selected by DOE | Department of Energy Addressing Technical Challenges to Environmentally Acceptable Shale Gas Development Selected by DOE Research Projects Addressing Technical Challenges to Environmentally Acceptable Shale Gas Development Selected by DOE November 28, 2012 - 12:00pm Addthis Washington, DC - Fifteen research projects aimed at addressing the technical challenges of producing natural gas from shales and tight sands, while simultaneously

  10. Addressing Deferred Maintenance, Infrastructure Costs, and Excess

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Facilities at Portsmouth and Paducah | Department of Energy Addressing Deferred Maintenance, Infrastructure Costs, and Excess Facilities at Portsmouth and Paducah Addressing Deferred Maintenance, Infrastructure Costs, and Excess Facilities at Portsmouth and Paducah Presentation from the 2015 DOE National Cleanup Workshop by William E. Murphie, Manager, Portsmouth/Paducah Project Office (PPPO). PDF icon Addressing Deferred Maintenance, Infrastructure Costs, and Excess Facilities at Portsmouth

  11. Recommendations to Address Power Reliability Concerns Raised...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Memorandum from the Electricity Advisory Committee to Secretary Chu and Assistant Secretary Patricia Hoffman on recommendations to address power reliability concerns raised as a ...

  12. POLICY GUIDANCE MEMORANDUM #03 Addressing Missclassified Positions...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    PDF icon POLICY GUIDANCE MEMORANDUM 3A Addressing Missclassified Positions Responsible Contacts Jennifer Ackerman Director, Human Capital Policy E-mail jennifer.ackerman@hq.doe.go...

  13. Mailing Addresses and Information Numbers for Operations, Field...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    U.S. Department of Energy Southwestern Power Administration One West Third Street Tulsa, OK 74103-3502 Headquarters, Operations and Maintenance Offices 918-595-6600 U.S. Department...

  14. EECBG Success Story: Recovery Act is "Lighting Up" the Streets of Philadelphia

    Broader source: Energy.gov [DOE]

    The Philadelphia Streets Department is converting 58,000 yellow and green traffic signals and will replace approximately 27,000 red LED lights that have come to the end of their useful life. Learn more.

  15. DOE Zero Energy Ready Home Case Study: StreetScape Development, LLC, Libertyville, Illinois

    SciTech Connect (OSTI)

    none,

    2013-09-01

    These single-family, HERS 45 homes incorporate 26 wood framed walls with R-20 open cell spray insulation and OSB. The builder, StreetScape Development, won a 2013 Housing Innovation Award in the custom builder category.

  16. Building America Whole-House Solutions for Existing Homes: Conway Street

    Energy Savers [EERE]

    Apartments - Greenfield, Massachusetts | Department of Energy Conway Street Apartments - Greenfield, Massachusetts Building America Whole-House Solutions for Existing Homes: Conway Street Apartments - Greenfield, Massachusetts Through recent research efforts, CARB has been evaluating strategies and technologies that can make dramatic improvements in energy performance in multifamily buildings. In this project, the team helped to transform a 100-year-old empty school building into 12 high

  17. DOE - Office of Legacy Management -- GSA 39th Street Warehouse - IL 02

    Office of Legacy Management (LM)

    GSA 39th Street Warehouse - IL 02 FUSRAP Considered Sites Site: GSA 39TH STREET WAREHOUSE (IL.02 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: 1716 West Pershing Road , Chicago , Illinois IL.02-1 Evaluation Year: 1985 IL.02-2 IL.02-3 Site Operations: Stored radioactive materials. IL.02-1 IL.02-2 Site Disposition: Eliminated - Radiation levels below criteria IL.02-1 Radioactive Materials Handled: Yes Primary Radioactive Materials

  18. Tuesday Opening Address | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Tuesday Opening Address Tuesday Opening Address May 20, 2014 12:30PM to 1:00PM PDT Pacific Ballroom Featuring Minh Le, Director of the SunShot Initiative, and Ramamoorthy Ramesh, Deputy Director for Science and Technology at Oak Ridge National Laboratory

  19. 2015 State of Indian Nations Address

    Broader source: Energy.gov [DOE]

    The President of the National Congress of American Indians will deliver his annual State of the Indian Nations address to Member of Congress, government officials, tribal leaders and citizens, and...

  20. Federal Actions to Address Impacts of Uranium

    Office of Legacy Management (LM)

    Federal Actions to Address Impacts of Uranium Contamination in the Navajo Nation 2014 Page | i TABLE OF CONTENTS Executive Summary ....................................................................................................................... 1 Introduction .................................................................................................................................... 2 Summary of Work Completed 2008-2012

  1. DOE - Office of Legacy Management -- Mitts-Merrel Co - MI 14

    Office of Legacy Management (LM)

    Mitts-Merrel Co - MI 14 FUSRAP Considered Sites Site: MITTS-MERREL CO. (MI.14 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: Mitts & Merrell Co. MI.14-1 Location: Saginaw , Michigan MI.14-1 Evaluation Year: 1993 MI.14-2 Site Operations: Reduced thorium metal chunks into particle sized pieces on a small test scale during the mid-1950s. MI.14-1 Site Disposition: Eliminated - Potential for contamination considered remote based on limited quantity of

  2. DOE - Office of Legacy Management -- Naval Ordnance Plant - MI 0-03

    Office of Legacy Management (LM)

    Plant - MI 0-03 FUSRAP Considered Sites Site: NAVAL ORDNANCE PLANT (MI.0-03) Eliminated from further consideration under FUSRAP - Referred to DoD for action Designated Name: Not Designated Alternate Name: None Location: Centerline , Michigan MI.0-03-1 Evaluation Year: 1987 MI.0-03-1 Site Operations: Assembled bomb components. MI.0-03-1 Site Disposition: Eliminated - No Authority - Referred to DoD MI.0-03-1 Radioactive Materials Handled: None Indicated Primary Radioactive Materials Handled: None

  3. DOE - Office of Legacy Management -- Dow-Detroit Edison Project - MI 0-02

    Office of Legacy Management (LM)

    Dow-Detroit Edison Project - MI 0-02 FUSRAP Considered Sites Site: Dow-Detroit Edison Project (MI.0-02 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Detroit , Michigan MI.0-02-1 Evaluation Year: 1987 MI.0-02-1 Site Operations: Performed reference design work for a special fast breeder type reactor. MI.0-02-1 Site Disposition: Eliminated - No radioactive material handled at the site MI.0-02-1 Radioactive Materials Handled: No

  4. miRNA-205 affects infiltration and metastasis of breast cancer

    SciTech Connect (OSTI)

    Wang, Zhouquan; Department of Tumor, SenGong Hospital of Shaanxi, Xian 710300 ; Liao, Hehe; Deng, Zhiping; Yang, Po; Du, Ning; Zhanng, Yunfeng; Ren, Hong

    2013-11-08

    Highlights: We detected expression of miR-205 in breast cancer cell lines and tissue samples. We suggest miR-205 is downregulated in human breast cancer tissues and MCF7 cells. We suggest the lower expression of miR-205 play a role in breast cancer onset. These data suggest that miR-205 directly targets HER3 in human breast cancer. -- Abstract: Background: An increasing number of studies have shown that miRNAs are commonly deregulated in human malignancies, but little is known about the function of miRNA-205 (miR-205) in human breast cancer. The present study investigated the influence of miR-205 on breast cancer malignancy. Methods: The expression level of miR-205 in the MCF7 breast cancer cell line was determined by quantitative (q)RT-PCR. We then analyzed the expression of miR-205 in breast cancer and paired non-tumor tissues. Finally, the roles of miR-205 in regulating tumor proliferation, apoptosis, migration, and target gene expression were studied by MTT assay, flow cytometry, qRT-PCR, Western blotting and luciferase assay. Results: miR-205 was downregulated in breast cancer cells or tissues compared with normal breast cell lines or non-tumor tissues. Overexpression of miR-205 reduced the growth and colony-formation capacity of MCF7 cells by inducing apoptosis. Overexpression of miR-205 inhibited MCF7 cell migration and invasiveness. By bioinformation analysis, miR-205 was predicted to bind to the 3? untranslated regions of human epidermal growth factor receptor (HER)3 mRNA, and upregulation of miR-205 reduced HER3 protein expression. Conclusion: miR-205 is a tumor suppressor in human breast cancer by post-transcriptional inhibition of HER3 expression.

  5. Port Huron, MI Liquefied Natural Gas Exports (Million Cubic Feet)

    U.S. Energy Information Administration (EIA) Indexed Site

    (Million Cubic Feet) Port Huron, MI Liquefied Natural Gas Exports (Million Cubic Feet) Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2013 1 2014 1 1 1 1 2 1 1 1 1 1 2015 1 1 1 1 1 - = No Data Reported; -- = Not Applicable; NA = Not Available; W = Withheld to avoid disclosure of individual company data. Release Date: 02/29/2016 Next Release Date: 03/31/2016 Referring Pages: U.S. Liquefied Natural Gas Exports by Point of Exit Port Huron, MI LNG Exports to All Countries

  6. parking permit application - front

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    POSITION TITLE MI FIRST NAME LAST NAME HOME ADDRESS (Street, City, State) EMPLOYER DOE ROUTE SYMBOL WORK PHONE EXT SIGNATURE ST CAR NO 1, MAKE TAG NUMBER ST TAG NUMBER CAR NO 2, MAKE YEARS FEDERAL SERVICE POSITION TITLE MI FIRST NAME LAST NAME HOME ADDRESS (Street, City, State) EMPLOYER DOE ROUTE SYMBOL WORK PHONE EXT INSTRUCTIONS: Complete requested information in each applicable blank. For make of car: Use Ford, Chevrolet, Plymouth, Toyota, Volkswagen, etc., Not model name. Return original

  7. Shared address collectives using counter mechanisms

    DOE Patents [OSTI]

    Blocksome, Michael; Dozsa, Gabor; Gooding, Thomas M; Heidelberger, Philip; Kumar, Sameer; Mamidala, Amith R; Miller, Douglas

    2014-02-18

    A shared address space on a compute node stores data received from a network and data to transmit to the network. The shared address space includes an application buffer that can be directly operated upon by a plurality of processes, for instance, running on different cores on the compute node. A shared counter is used for one or more of signaling arrival of the data across the plurality of processes running on the compute node, signaling completion of an operation performed by one or more of the plurality of processes, obtaining reservation slots by one or more of the plurality of processes, or combinations thereof.

  8. Cheaper Adjoints by Reversing Address Computations

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Hascoët, L.; Utke, J.; Naumann, U.

    2008-01-01

    The reverse mode of automatic differentiation is widely used in science and engineering. A severe bottleneck for the performance of the reverse mode, however, is the necessity to recover certain intermediate values of the program in reverse order. Among these values are computed addresses, which traditionally are recovered through forward recomputation and storage in memory. We propose an alternative approach for recovery that uses inverse computation based on dependency information. Address storage constitutes a significant portion of the overall storage requirements. An example illustrates substantial gains that the proposed approach yields, and we show use cases in practical applications.

  9. DOE - Office of Legacy Management -- Amex Specialty Metal Corp - MI 0-01

    Office of Legacy Management (LM)

    Amex Specialty Metal Corp - MI 0-01 FUSRAP Considered Sites Site: Amex Specialty Metal Corp (MI.0-01 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Coldwater , Michigan MI.0-01-1 Evaluation Year: 1987 MI.0-01-1 Site Operations: No indication that AMEX performed work for MED or AEC activities. Originally included on FUSRAP list due to fact that AMEX purchased milling equipment from a company that had done uranium milling.

  10. Mapping virtual addresses to different physical addresses for value disambiguation for thread memory access requests

    DOE Patents [OSTI]

    Gala, Alan; Ohmacht, Martin

    2014-09-02

    A multiprocessor system includes nodes. Each node includes a data path that includes a core, a TLB, and a first level cache implementing disambiguation. The system also includes at least one second level cache and a main memory. For thread memory access requests, the core uses an address associated with an instruction format of the core. The first level cache uses an address format related to the size of the main memory plus an offset corresponding to hardware thread meta data. The second level cache uses a physical main memory address plus software thread meta data to store the memory access request. The second level cache accesses the main memory using the physical address with neither the offset nor the thread meta data after resolving speculation. In short, this system includes mapping of a virtual address to a different physical addresses for value disambiguation for different threads.

  11. DOE Zero Energy Ready Home Case Study: StreetScape Development, LLC,

    Energy Savers [EERE]

    Libertyville, IL, Custom | Department of Energy StreetScape Development, LLC, Libertyville, IL, Custom DOE Zero Energy Ready Home Case Study: StreetScape Development, LLC, Libertyville, IL, Custom Case study of a DOE Zero Energy Ready Home in Libertyville, IL, that scored HERS 45 without PV. This 2,763-square-foot custom home has advanced framed walls with R-20 of open-cell spray foam, R-49 open-cell spray-foam sealed attic, an HRV, and a tankless water heater for hydro coil furnace with

  12. Working with Cities to Light Our Streets Better | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Cities to Light Our Streets Better Working with Cities to Light Our Streets Better January 26, 2015 - 9:18pm Addthis Franklin (Lynn) Orr Franklin (Lynn) Orr Under Secretary for Science and Energy Last week, mayors from around the nation visited Washington, D.C., for the U.S. Conference of Mayors' annual winter meeting. During a White House briefing, I had the chance to meet with 30 mayors who are committed to tackling today's energy and climate challenges. Cities are on the frontlines of

  13. Radiosensitizing Effects of Ectopic miR-101 on Non-Small-Cell Lung Cancer Cells Depend on the Endogenous miR-101 Level

    SciTech Connect (OSTI)

    Chen, Susie; Wang Hongyan; Ng, Wooi Loon; Curran, Walter J.; Wang Ya

    2011-12-01

    Purpose: Previously, we showed that ectopic miR-101 could sensitize human tumor cells to radiation by targeting ATM and DNA-PK catalytic subunit (DNA-PKcs) to inhibit DNA repair, as the endogenous miR-101 levels are low in tumors in general. However, the heterogeneity of human cancers may result in an exception. The purpose of this study was to test the hypothesis that a few tumor cell lines with a high level of endogenous miR-101 would prove less response to ectopic miR-101. Methods and Materials: Fourteeen non-small-cell lung cancer (NSCLC) cell lines and one immortalized non-malignant lung epithelial cell line (NL20) were used for comparing endogenous miR-101 levels by real-time reverse transcription-polymerase chain reaction. Based on the different miR-101 levels, four cell lines with different miR-101 levels were chosen for transfection with a green fluorescent protein-lentiviral plasmid encoding miR-101. The target protein levels were measured by using Western blotting. The radiosensitizing effects of ectopic miR-101 on these NSCLC cell lines were determined by a clonogenic assay and xenograft mouse model. Results: The endogenous miR-101 level was similar or lower in 13 NSCLC cell lines but was 11-fold higher in one cell line (H157) than in NL20 cells. Although ectopic miR-101 efficiently decreased the ATM and DNA-PKcs levels and increased the radiosensitization level in H1299, H1975, and A549 cells, it did not change the levels of the miR-101 targets or radiosensitivity in H157 cells. Similar results were observed in xenograft mice. Conclusions: A small number of NSCLC cell lines could have a high level of endogenous miR-101. The ectopic miR-101 was able to radiosensitize most NSCLC cells, except for the NSCLC cell lines that had a much higher endogenous miR-101 level. These results suggest that when we choose one miRNA as a therapeutic tool, the endogenous level of the miRNA in each tumor should be considered.

  14. Enhancing Energy Infrastructure Resiliency and Addressing Vulnerabilities

    Broader source: Energy.gov [DOE]

    Quadrennial Energy Review Task Force Secretariat and Energy Policy and Systems Analysis Staff, U. S. Department of Energy (DOE) Public Meeting on “Enhancing Resilience in Energy Infrastructure and Addressing Vulnerabilities” On Friday, April 11, 2014, at 10 a.m. in room HVC-215 of the U.S. Capitol, the Department of Energy (DOE), acting as the Secretariat for the Quadrennial Energy Review Task Force, will hold a public meeting to discuss and receive comments on issues related to the Quadrennial Energy Review (QER). The meeting will focus on infrastructure vulnerabilities related to the electricity, natural gas and petroleum transmission, storage and distribution systems (TS&D). The meeting will consist of two facilitated panels of experts on identifying and addressing vulnerabilities within the nation’s energy TS&D infrastructure. Following the panels, an opportunity will be provided for public comment via an open microphone session. The meeting will be livestreamed at energy.gov/live

  15. Global-Address Space Networking (GASNet) Library

    Energy Science and Technology Software Center (OSTI)

    2011-04-06

    GASNet (Global-Address Space Networking) is a language-independent, low-level networking layer that provides network-independent, high-performance communication primitives tailored for implementing parallel global address space SPMD languages such as UPC and Titanium. The interface is primarily intended as a compilation target and for use by runtime library writers (as opposed to end users), and the primary goals are high performance, interface portability, and expressiveness. GASNet is designed specifically to support high-performance, portable implementations of global address spacemore » languages on modern high-end communication networks. The interface provides the flexibility and extensibility required to express a wide variety of communication patterns without sacrificing performance by imposing large computational overheads in the interface. The design of the GASNet interface is partitioned into two layers to maximize porting ease without sacrificing performance: the lower level is a narrow but very general interface called the GASNet core API - the design is basedheavily on Active Messages, and is implemented directly on top of each individual network architecture. The upper level is a wider and more expressive interface called GASNet extended API, which provides high-level operations such as remote memory access and various collective operations. This release implements GASNet over MPI, the Quadrics "elan" API, the Myrinet "GM" API and the "LAPI" interface to the IBM SP switch. A template is provided for adding support for additional network interfaces.« less

  16. Demonstration Assessment of Light-Emitting Diode (LED) Street Lighting Host Site: Lija Loop, Portland, Oregon

    SciTech Connect (OSTI)

    Kinzey, Bruce R.; Myer, Michael

    2009-11-01

    This report describes the process and results of a demonstration of solid-state lighting (SSL) technology in a residential street lighting application, under the U.S. Department of Energy GATEWAY Solid-State Lighting Technology Demonstration Program. In this project, eight 100W (nominal) high-pressure sodium cobra head fixtures were replaced with a like number of LED street light luminaires manufactured by Leotek, Inc. The Leotek product achieved an estimated payback in the Lija Loop installation of about 20 years for replacement scenarios and a much shorter 7.6 years for new installations. Much of the associated energy savings (55%) supporting these payback periods, however, were achieved by reducing average horizontal photopic illuminance a similar amount (53%). Examined from a different perspective, the measured performance suggests that the Leotek product is at approximate parity with the HPS cobra head in terms of average delivered photopic illumination for a given power consumption. HPS comprises the second most efficacious street lighting technology available, exceeded only by low pressure sodium (LPS). LPS technology is not considered suitable for most street lighting applications due to its monochromatic spectral output and poor color rendering ability; therefore, this LED product is performing at an efficiency level comparable to its primary competition in this application.

  17. Executive summary of major NuMI lessons learned: a review of relevant meetings of Fermilab's DUSEL Beamline Working Group

    SciTech Connect (OSTI)

    Andrews, Mike; Appel, Jeffrey A.; Bogert, Dixon; Childress, Sam; Cossairt, Don; Griffing, William; Grossman, Nancy; Harding, David; Hylen, Jim; Kuchler, Vic; Laughton, Chris; /Fermilab /Argonne /Brookhaven /LBL, Berkeley

    2009-05-01

    We have gained tremendous experience with the NuMI Project on what was a new level of neutrino beams from a high power proton source. We expect to build on that experience for any new long baseline neutrino beam. In particular, we have learned about some things which have worked well and/or where the experience is fairly directly applicable to the next project (e.g., similar civil construction issues including: tunneling, service buildings, outfitting, and potential claims/legal issues). Some things might be done very differently (e.g., decay pipe, windows, target, beam dump, and precision of power supply control/monitoring). The NuMI experience does lead to identification of critical items for any future such project, and what issues it will be important to address. The DUSEL Beamline Working Group established at Fermilab has been meeting weekly to collect and discuss information from that NuMI experience. This document attempts to assemble much of that information in one place. In this Executive Summary, we group relevant discussion of some of the major issues and lessons learned under seven categories: (1) Differences Between the NuMI Project and Any Next Project; (2) The Process of Starting Up the Project; (3) Decision and Review Processes; (4) ES&H: Environment, Safety, and Health; (5) Local Community Buy-In; (6) Transition from Project Status to Operation; and (7) Some Lessons on Technical Elements. We concentrate here on internal project management issues, including technical areas that require special attention. We cannot ignore, however, two major external management problems that plagued the NuMI project. The first problem was the top-down imposition of an unrealistic combination of scope, cost, and schedule. This situation was partially corrected by a rebaselining. However, the full, desirable scope was never achievable. The second problem was a crippling shortage of resources. Critical early design work could not be done in a timely fashion, leading to schedule delays, inefficiencies, and corrective actions. The Working Group discussions emphasized that early planning and up-front appreciation of the problems ahead are very important for minimizing the cost and for the greatest success of any such project. Perhaps part of the project approval process should re-enforce this need. The cost of all this up-front work is now reflected in the DOE cost of any project we do. If we are being held to an upper limit on the project cost, the only thing available for compromise is the eventual project scope.

  18. miR-30a suppresses breast cancer cell proliferation and migration by targeting Eya2

    SciTech Connect (OSTI)

    Fu, Jing; Xu, Xiaojie; Kang, Lei; Zhou, Liying; Wang, Shibin; Lu, Juming; Cheng, Long; Fan, Zhongyi; Yuan, Bin; Tian, Peirong; Zheng, Xiaofei; Yu, Chengze; Ye, Qinong; Lv, Zhaohui

    2014-03-07

    Highlights: miR-30a represses Eya2 expression by binding to the 3?-untranslated region of Eya2. The miR-30a/EYA2 axis regulates breast cancer cell proliferation and migration. The miR-30a/EYA2 axis modulates G1/S cell cycle progression. The miR-30a/EYA2 axis is dysregulated in breast cancer patients. - Abstract: Eye absent (Eya) proteins are involved in cell fate determination in a broad spectrum of cells and tissues. Aberrant expression of Eya2 has been documented in a variety of cancers and correlates with clinical outcome. However, whether microRNAs (miRNAs) can regulate Eya2 expression remains unknown. Here, we show that miR-30a represses Eya2 expression by binding to the 3?-untranslated region of Eya2. Overexpression of Eya2 in miR-30a-transfected breast cancer cells effectively rescued the inhibition of cell proliferation and migration caused by miR-30a. Knockdown of Eya2 by small-interfering RNA (siRNA) in breast cancer cells mimicked the effect induced by miR-30a and abolished the ability of miR-30a to regulate breast cancer cell proliferation and migration. The miR-30a/Eya2 axis could regulate G1/S cell cycle progression, accompanied by the modulation of expression of cell cycle-related proteins, including cyclin A, cyclin D1, cyclin E, and c-Myc. Moreover, miR-30a expression was downregulated in breast cancer patients, and negatively correlated with Eya2, which was upregulated in breast cancer patients. These data suggest that the miR-30a/Eya2 axis may play an important role in breast cancer development and progression and that miR-30a activation or Eya2 inhibition may be a useful strategy for cancer treatment.

  19. Superfund Record of Decision (EPA Region 2): Hooker-102nd Street Landfill, Niagara Falls, NY. (First remedial action), September 1990. Final report

    SciTech Connect (OSTI)

    Not Available

    1990-09-26

    The 22-acre Hooker-102nd Street site is a former industrial landfill in the city of Niagara Falls, Niagara County, New York. The site is adjacent to, and partially within the Niagara River's 100-year floodplain. These studies and the Remedial Investigation (RI) initiated in 1984, identified contamination in ground water, onsite and offsite soil, rivershore sediment, and within a storm sewer. Additionally, the presence of a leachate plume of non-aqueous phase liquids (NAPLs) was discovered emanating from the landfill area. The Record of Decision (ROD) is the final remedy which addresses all of the contaminated media. The primary contaminants of concern affecting the soil, sediment, and ground water are VOCs including benzene, TCE, and toluene; other organics including PCBs and phenols; and metals including arsenic.

  20. Framework for Address Cooperative Extended Transactions

    Energy Science and Technology Software Center (OSTI)

    1997-12-01

    The Framework for Addressing Cooperative Extended Transactions (FACET) is an object-oriented software framework for building models of complex, cooperative behaviors of agents. it can be used to implement simulation models of societal processes such as the complex interplay of participating individuals and organizations engaged in multiple concurrent transactions in pursuit of their various goals. These transactions can be patterned on, for example, clinical guidelines and procedures, business practices, government and corporate policies, etc. FACET canmore »also address other complex behaviors such as biological life cycles or manufacturing processes. FACET includes generic software objects representing the fundamental classes of agent -- Person and Organization - with mechanisms for resource management, including resolution of conflicting requests for participation and/or use of the agent's resources. The FACET infrastructure supports stochastic behavioral elements and coping mechanisms by which specified special conditions and events can cause an active cooperative process to be preempted, diverting the participants onto appropriate alternative behavioral pathways.« less

  1. Bush Administration Plays Leading Role in Studying and Addressing...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Bush Administration Plays Leading Role in Studying and Addressing Global Climate Change Bush Administration Plays Leading Role in Studying and Addressing Global Climate Change...

  2. Smart Grid RFI: Addressing Policy and Logistical Challenges....

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Smart Grid RFI: Addressing Policy and Logistical Challenges. Comments of the Alliance to Save Energy. Smart Grid RFI: Addressing Policy and Logistical Challenges. Comments of the...

  3. New York Independent System Operator, Smart Grid RFI: Addressing...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    York Independent System Operator, Smart Grid RFI: Addressing Policy and Logistical Challenges. New York Independent System Operator, Smart Grid RFI: Addressing Policy and...

  4. Protocol for Addressing Induced Seismicity Associated with Enhanced...

    Energy Savers [EERE]

    Protocol for Addressing Induced Seismicity Associated with Enhanced Geothermal Systems Protocol for Addressing Induced Seismicity Associated with Enhanced Geothermal Systems This...

  5. Opportunities for Building America Research to Address Energy...

    Energy Savers [EERE]

    Opportunities for Building America Research to Address Energy Upgrade Technical Challenges: HVAC, Envelope and IAQ (301) Opportunities for Building America Research to Address...

  6. Assistant Secretary Patricia Hoffman to Deliver Keynote Address...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Patricia Hoffman to Deliver Keynote Address at IEEE PES Conference on Innovative Smart Grid Technologies Assistant Secretary Patricia Hoffman to Deliver Keynote Address at IEEE PES ...

  7. Bush Administration Plays Leading Role in Studying and Addressing...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Plays Leading Role in Studying and Addressing Global Climate Change Bush Administration Plays Leading Role in Studying and Addressing Global Climate Change February 27, 2007 - ...

  8. Addressing Biomass Supply Chain Challenges With AFEX(tm) Technology...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Addressing Biomass Supply Chain Challenges With AFEX(tm) Technology Addressing Biomass Supply Chain Challenges With AFEX(tm) Technology Plenary IV: Advances in Bioenergy ...

  9. Southern Company: DOE Smart Grid RFI Addressing Policy and Logistical...

    Office of Environmental Management (EM)

    Southern Company: DOE Smart Grid RFI Addressing Policy and Logistical Challenges Southern Company: DOE Smart Grid RFI Addressing Policy and Logistical Challenges Southern Company:...

  10. Policy Agenda for Addressing Climate Change in Bangladesh: Copenhagen...

    Open Energy Info (EERE)

    Agenda for Addressing Climate Change in Bangladesh: Copenhagen and Beyond Jump to: navigation, search Name Policy Agenda for Addressing Climate Change in Bangladesh: Copenhagen and...

  11. Indonesia National Action Plan Addressing Climate Change | Open...

    Open Energy Info (EERE)

    National Action Plan Addressing Climate Change Jump to: navigation, search Tool Summary LAUNCH TOOL Name: Indonesia National Action Plan Addressing Climate Change AgencyCompany...

  12. Addressing the Need for Alternative Transportation Fuels: The...

    Office of Scientific and Technical Information (OSTI)

    Addressing the Need for Alternative Transportation Fuels: The Joint BioEnergy Institute Citation Details In-Document Search Title: Addressing the Need for Alternative ...

  13. Protocol for Addressing Induced Seismicity Associated with Enhanced...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Protocol for Addressing Induced Seismicity Associated with Enhanced Geothermal Systems (EGS) Protocol for Addressing Induced Seismicity Associated with Enhanced Geothermal Systems...

  14. Addressing Uncertainties in Design Inputs: A Case Study of Probabilist...

    Office of Environmental Management (EM)

    Addressing Uncertainties in Design Inputs: A Case Study of Probabilistic Settlement Evaluations for Soft Zone Collapse at SWPF Addressing Uncertainties in Design Inputs: A Case...

  15. Progress Energy draft regarding Smart Grid RFI: Addressing Policy...

    Broader source: Energy.gov (indexed) [DOE]

    Progress Energy draft regarding Smart Grid RFI: Addressing Policy and Logistical Challenges Progress Energy draft regarding Smart Grid RFI: Addressing Policy and Logistical...

  16. Strategies to Address Split Incentives in Multifamily Buildings...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Strategies to Address Split Incentives in Multifamily Buildings Better Buildings Neighborhood Program Multifamily Low-Income Peer Exchange Call: Strategies to Address Split ...

  17. NAP Coalition Response to DOE RFI: Addressing Policy and Logistical...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    NAP Coalition Response to DOE RFI: Addressing Policy and Logistical Challenges to Smart Grid Implementation NAP Coalition Response to DOE RFI: Addressing Policy and Logistical ...

  18. NBP RFI-Addressing Policy and Logistical Challenges to Smart...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    NBP RFI-Addressing Policy and Logistical Challenges to Smart Grid Implementation. September 10, 2009 NBP RFI-Addressing Policy and Logistical Challenges to Smart Grid ...

  19. Okaloosa Gas District Smart Grid RFI: Addressing Policy and Logistical...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Okaloosa Gas District Smart Grid RFI: Addressing Policy and Logistical Challenges to Smart Grid Implementation Okaloosa Gas District Smart Grid RFI: Addressing Policy and ...

  20. Response to Request for Information titled "Addressing Policy...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    to Request for Information titled "Addressing Policy and Logistical Challenges to Smart Grid Implementation" Response to Request for Information titled "Addressing Policy and ...

  1. The INL Seismic Risk Assessment Project: Requirements for Addressing...

    Office of Environmental Management (EM)

    Project: Requirements for Addressing DOE Order 420.1C & A Proposed Generic Methodology The INL Seismic Risk Assessment Project: Requirements for Addressing DOE Order...

  2. DOE Seeks Input On Addressing Contractor Pension and Medical...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Input On Addressing Contractor Pension and Medical Benefits Liabilities DOE Seeks Input On Addressing Contractor Pension and Medical Benefits Liabilities March 27, 2007 - 12:10pm...

  3. Addressable morphology control of silica structures by manipulating...

    Office of Scientific and Technical Information (OSTI)

    Addressable morphology control of silica structures by manipulating the reagent addition time Citation Details In-Document Search Title: Addressable morphology control of silica ...

  4. Addressing the Voltage Fade Issue with Lithium-Manganese-Rich...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Addressing the Voltage Fade Issue with Lithium-Manganese-Rich Oxide Cathode Materials Addressing the Voltage Fade Issue with Lithium-Manganese-Rich Oxide Cathode Materials 2013 DOE...

  5. Pecan Street Smart Grid Extension Service at the University of Texas

    SciTech Connect (OSTI)

    McCracken, Brewster

    2014-02-11

    Through funding from the Department of Energy’s Electricity Delivery and Reliability Office, Pecan Street Inc., in partnership with Austin Energy and Oncor, developed and tested third- party data access platforms and services for Green Button offerings and for other home energy use data providers. As more utilities seek to offer Green Button-compliant data to their customers, the question continually arises of how this data can be used to help customers better manage their energy use.

  6. The Municipal Solid-State Street Lighting Consortium Public Outdoor Lighting Inventory: Phase I: Survey Results

    SciTech Connect (OSTI)

    Kinzey, Bruce R.; Smalley, Edward; Haefer, R.

    2014-09-30

    This document presents the results of a voluntary web-based inventory survey of public street and area lighting across the U.S. undertaken during the latter half of 2013.This survey attempts to access information about the national inventory in a bottoms-up manner, going directly to owners and operators. Adding to previous top down estimates, it is intended to improve understanding of the role of public outdoor lighting in national energy use.

  7. Main Street Net-Zero Energy Buildings: The Zero Energy Method in Concept and Practice

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    870 July 2010 Main Street Net-Zero Energy Buildings: The Zero Energy Method in Concept and Practice Preprint Paul Torcellini, Shanti Pless, and Chad Lobato National Renewable Energy Laboratory Tom Hootman RNL Design Presented at the ASME 2010 4 th International Conference on Energy Sustainability Phoenix, Arizona May 17-22, 2010 NOTICE The submitted manuscript has been offered by an employee of the Alliance for Sustainable Energy, LLC (ASE), a contractor of the US Government under Contract No.

  8. Hr. Michael Esposito Audio-Tex Industries, Incorporated 4555 West Addison Street

    Office of Legacy Management (LM)

    -- Hr. Michael Esposito Audio-Tex Industries, Incorporated 4555 West Addison Street Chicago, Illinois 60641 Dear Mr. Esposito: Enclosed is a copy of the final survey report for your facility in Chicago,. Illinois , which is the site of the former ERA Tool & Engineering Company. The survey report documents the fact that the radiological condition of your facility is in compliance with applicable Department of Energy Guidelines and that no remedial action or further investigaticns are

  9. Genome-Wide Analysis of miRNA targets in Brachypodium and Biomass Energy Crops

    SciTech Connect (OSTI)

    Green, Pamela J.

    2015-08-11

    MicroRNAs (miRNAs) contribute to the control of numerous biological processes through the regulation of specific target mRNAs. Although the identities of these targets are essential to elucidate miRNA function, the targets are much more difficult to identify than the small RNAs themselves. Before this work, we pioneered the genome-wide identification of the targets of Arabidopsis miRNAs using an approach called PARE (German et al., Nature Biotech. 2008; Nature Protocols, 2009). Under this project, we applied PARE to Brachypodium distachyon (Brachypodium), a model plant in the Poaceae family, which includes the major food grain and bioenergy crops. Through in-depth global analysis and examination of specific examples, this research greatly expanded our knowledge of miRNAs and target RNAs of Brachypodium. New regulation in response to environmental stress or tissue type was found, and many new miRNAs were discovered. More than 260 targets of new and known miRNAs with PARE sequences at the precise sites of miRNA-guided cleavage were identified and characterized. Combining PARE data with the small RNA data also identified the miRNAs responsible for initiating approximately 500 phased loci, including one of the novel miRNAs. PARE analysis also revealed that differentially expressed miRNAs in the same family guide specific target RNA cleavage in a correspondingly tissue-preferential manner. The project included generation of small RNA and PARE resources for bioenergy crops, to facilitate ongoing discovery of conserved miRNA-target RNA regulation. By associating specific miRNA-target RNA pairs with known physiological functions, the research provides insights about gene regulation in different tissues and in response to environmental stress. This, and release of new PARE and small RNA data sets should contribute basic knowledge to enhance breeding and may suggest new strategies for improvement of biomass energy crops.

  10. DLEU2, frequently deleted in malignancy, functions as a critical host gene of the cell cycle inhibitory microRNAs miR-15a and miR-16-1

    SciTech Connect (OSTI)

    Lerner, Mikael; Harada, Masako; Loven, Jakob; Castro, Juan; Davis, Zadie; Oscier, David; Henriksson, Marie; Sangfelt, Olle; Grander, Dan; Corcoran, Martin M.

    2009-10-15

    The microRNAs miR-15a and miR-16-1 are downregulated in multiple tumor types and are frequently deleted in chronic lymphocytic leukemia (CLL), myeloma and mantle cell lymphoma. Despite their abundance in most cells the transcriptional regulation of miR-15a/16-1 remains unclear. Here we demonstrate that the putative tumor suppressor DLEU2 acts as a host gene of these microRNAs. Mature miR-15a/miR-16-1 are produced in a Drosha-dependent process from DLEU2 and binding of the Myc oncoprotein to two alterative DLEU2 promoters represses both the host gene transcript and levels of mature miR-15a/miR-16-1. In line with a functional role for DLEU2 in the expression of the microRNAs, the miR-15a/miR-16-1 locus is retained in four CLL cases that delete both promoters of this gene and expression analysis indicates that this leads to functional loss of mature miR-15a/16-1. We additionally show that DLEU2 negatively regulates the G1 Cyclins E1 and D1 through miR-15a/miR-16-1 and provide evidence that these oncoproteins are subject to miR-15a/miR-16-1-mediated repression under normal conditions. We also demonstrate that DLEU2 overexpression blocks cellular proliferation and inhibits the colony-forming ability of tumor cell lines in a miR-15a/miR-16-1-dependent way. Together the data illuminate how inactivation of DLEU2 promotes cell proliferation and tumor progression through functional loss of miR-15a/miR-16-1.

  11. Microfluidic Molecular Assay Platform for the Detection of miRNAs...

    Office of Scientific and Technical Information (OSTI)

    Article: Microfluidic Molecular Assay Platform for the Detection of miRNAs, mRNAs, Proteins, and Post-translational Modifications at Single-cell Resolution. Citation Details...

  12. Final Report on Internet Addressable Lightswitch

    SciTech Connect (OSTI)

    Rubinstein, Francis; Pettler, Peter

    2001-08-27

    This report describes the work performed to develop and test a new switching system and communications network that is useful for economically switching lighting circuits in existing commercial buildings. The first section of the report provides the general background of the IBECS (Integrated Building Environmental Communications System) research and development work as well as the context for the development of the new switching system. The research and development effort that went into producing the first proof-of-concept (the IBECS Addressable Power Switch or APS) and the physical prototype of that concept is detailed in the second section. In the third section of the report, we detail the refined Powerline Carrier Based IBECS Title 24 Wall Switch system that evolved from the APS prototype. The refined system provided a path for installing IBECS switching technology in existing buildings that may not be already wired for light level switching control. The final section of the report describes the performance of the IBECS Title 24 Switch system as applied to a small demonstration in two offices at LBNL's Building 90. We learned that the new Powerline Carrier control systems (A-10 technology) that have evolved from the early X-10 systems have solved most of the noise problems that dogged the successful application of X-10 technologies in commercial buildings. We found that the new A-10 powerline carrier control technology can be reliable and effective for switching lighting circuits even in electrically noisy office environments like LBNL. Thus we successfully completed the task objectives by designing, building and demonstrating a new switching system that can provide multiple levels of light which can be triggered either from specially designed wall switches or from a digital communications network. By applying commercially available powerline carrier based technologies that communicate over the in-place lighting wiring system, this type of control can be economi cally installed even in existing buildings that were not wired for dual-level lighting.

  13. Groundwater protection for the NuMI project

    SciTech Connect (OSTI)

    Wehmann, A.; Smart, W.; Menary, S.; Hylen, J.; Childress, S.

    1997-10-01

    The physics requirements for the long base line neutrino oscillation experiment MINOS dictate that the NuMI beamline be located in the aquifer at Fermilab. A methodology is described for calculating the level of radioactivation of groundwater caused by operation of this beamline. A conceptual shielding design for the 750 meter long decay pipe is investigated which would reduce radioactivation of the groundwater to below government standards. More economical shielding designs to meet these requirements are being explored. Also, information on local geology, hydrogeology, government standards, and a glossary have been included.

  14. REC Silicon formerly ASiMI | Open Energy Information

    Open Energy Info (EERE)

    ,"searchmarkers":"","locations":"text":"","title":"","link":null,"lat":47.838435,"lon":-100.665669,"alt":0,"address":"","icon":"","group":"","inlineLabel":"","visitedicon":""...

  15. Radiological survey results at 14 Cliff Street, Beverly, Massachusetts (VB011)

    SciTech Connect (OSTI)

    Foley, R.D.; Carrier, R.F.

    1992-08-01

    At the request of the US Department of Energy (DOE), a team from Oak Ridge National Laboratory conducted a radiological survey at 14 Cliff Street, Beverly, Massachusetts. The survey was performed in May 1991. The purpose of the survey was to determine if uranium dust from work performed under government contract at the former Ventron facility had migrated off-site to neighboring areas. The survey included a surface gamma scan and the collection of soil samples for radionuclide analyses. Results of the survey demonstrated no radionuclide concentrations or radiation measurements in excess of the DOE Formerly Utilized Sites Remedial Action Program guidelines.

  16. DOE Zero Ready Home Case Study: M Street Homes, Smartlux on Greenpark, Houston, TX

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    M Street Homes Smartlux on Greenpark Houston, TX DOE ZERO ENERGY READY HOME(tm) The U.S. Department of Energy invites home builders across the country to meet the extraordinary levels of excellence and quality specified in DOE's Zero Energy Ready Home program (formerly known as Challenge Home). Every DOE Zero Energy Ready Home starts with ENERGY STAR Certified Homes Version 3.0 for an energy-efficient home built on a solid foundation of building science research. Advanced technologies are

  17. FOLEY & LARDNER LLP ATTORNEYS AT LAW WASHINGTON HARBOUR 3000 K STREET, N.W.

    Office of Environmental Management (EM)

    FOLEY FOLEY & LARDNER LLP ATTORNEYS AT LAW WASHINGTON HARBOUR 3000 K STREET, N.W. SUITE 600 WASHINGTON, D.C. 20007-5109 202.672.5300 TEL 202.672.5399 FAX foley.com WRITER'S DIRECT LINE 202.672.5442 jsnewman©foley.corn EMAIL December 13, 2010 VIA E-Mail (Celia.Sher@hq.doe.gov) Ms. Celia Sher U.S. Department of Energy Office of General Counsel Forrestal Building, GC-71 1000 Independence Avenue, S.W. Washington, D.C. 585-0121 Re: Requested Summary of Telephone Conference Regarding

  18. The Honorable Richard M. Daley, Jr. 121 N. LaSalle Street

    Office of Legacy Management (LM)

    FEB 1 ? 1995 The Honorable Richard M. Daley, Jr. 121 N. LaSalle Street Chicago, Illinois 60602 Dear Mayor Daley: Y aa / 7 l- / J Secretary of Energy Hazel O'Leary has announced a new approach to openness in the Department of Energy (DOE) and its communications with the public. In support of this initiative, we are pleased to forward the enclosed information related to the former Podbeilniac Corp. site in your jurisdiction that performed work for DOE or its predecessor agencies. This information

  19. The Honorable Richard M. Daley,. Jr. 121 N.. LaSalle Street

    Office of Legacy Management (LM)

    Pepartment of Energy Washington, DC 20585 FEB 24 1995 The Honorable Richard M. Daley,. Jr. 121 N.. LaSalle Street Chicago, Illinoi~s 60602 Dear Mayor Daley:. Secretary of Energy Hazel O'Leary has announced a new approach.to openness in the Department.of Energy (DOE) and its communicationswith the public. In . support of this initiative, we are,pleased to.forward the enclosed information related to,the former Wyckoff Steel Co. site in your jurisdiction that performed work for DDE or its

  20. The Honorable Richard M., Daley, ~Jr: 121 N. LaSalle Street

    Office of Legacy Management (LM)

    Richard M., Daley, ~Jr: \ 121 N. LaSalle Street Chicago, Illinois 60602 ', Dear Mayor Daley.:' / Secretary-of Energy Hazel O'Leary has announced a new approach to openness in the Department of Energy (DOE) and its communications with the public. In support'of this .initiative, we are pleased to forward the.enclosed in7ormatio'n related to the former Crane Co. si,te in your jurisdiction 'that'performed work for DOE or.its predecessor agencies. information, use, and retention. , This in,formation-

  1. Addressing Barriers to Upgrade Projects at Affordable Multifamily

    Office of Environmental Management (EM)

    Properties (201) | Department of Energy Addressing Barriers to Upgrade Projects at Affordable Multifamily Properties (201) Addressing Barriers to Upgrade Projects at Affordable Multifamily Properties (201) March 10, 2016 1:00PM to 2:30PM EST

  2. Keynote Address: Billy Parish of Mosaic | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Billy Parish of Mosaic Keynote Address: Billy Parish of Mosaic May 20, 2014 3:00PM to 3:30PM PDT Pacific Ballroom Billy Parish, President and Founder of Mosaic, will address Summit attendees

  3. Progress Energy draft regarding Smart Grid RFI: Addressing Policy and

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Logistical Challenges | Department of Energy Progress Energy draft regarding Smart Grid RFI: Addressing Policy and Logistical Challenges Progress Energy draft regarding Smart Grid RFI: Addressing Policy and Logistical Challenges Progress Energy draft regarding Smart Grid RFI: Addressing Policy and Logistical Challenges PDF icon Progress Energy draft regarding Smart Grid RFI: Addressing Policy and Logistical Challenges More Documents & Publications Comments of DRSG to DOE Smart Grid RFI:

  4. Pepco Holdings, Inc. Smart Grid RFI: Addressing Policy and Logistical

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Challenges | Department of Energy Holdings, Inc. Smart Grid RFI: Addressing Policy and Logistical Challenges Pepco Holdings, Inc. Smart Grid RFI: Addressing Policy and Logistical Challenges Pepco Holdings, Inc. Smart Grid RFI: Addressing Policy and Logistical Challenges. Pepco Holdings, Inc. (PHI) is pleased to respond to the US Department of Energy (DOE) request for information regarding addressing policy and logistical challenges to smart grid implementation. This follows on the heels of

  5. Southern Company: DOE Smart Grid RFI Addressing Policy and Logistical

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Challenges | Department of Energy Southern Company: DOE Smart Grid RFI Addressing Policy and Logistical Challenges Southern Company: DOE Smart Grid RFI Addressing Policy and Logistical Challenges Southern Company: DOE Smart Grid RFI Addressing Policy and Logistical Challenges. Southern recognizes that many policy and logistical concerns must be addressed for the promises of smart grid technologies and applications to be fully realized in ways that are beneficial, secure, and cost-effective

  6. Individually addressable cathodes with integrated focusing stack or detectors

    DOE Patents [OSTI]

    Thomas, Clarence E.; Baylor, Larry R.; Voelkl, Edgar; Simpson, Michael L.; Paulus, Michael J.; Lowndes, Douglas; Whealton, John; Whitson, John C.; Wilgen, John B.

    2005-07-12

    Systems and method are described for addressable field emission array (AFEA) chips. A plurality of individually addressable cathodes are integrated with an electrostatic focusing stack and/or a plurality of detectors on the addressable field emission array. The systems and methods provide advantages including the avoidance of space-charge blow-up.

  7. Non-canonical microRNAs miR-320 and miR-702 promote proliferation in Dgcr8-deficient embryonic stem cells

    SciTech Connect (OSTI)

    Kim, Byeong-Moo; Choi, Michael Y.

    2012-09-21

    Highlights: Black-Right-Pointing-Pointer Embryonic stem cells (ESCs) lacking non-canonical miRNAs proliferate slower. Black-Right-Pointing-Pointer miR-320 and miR-702 are two non-canonical miRNAs expressed in ESCs. Black-Right-Pointing-Pointer miR-320 and miR-702 promote proliferation of Dgcr8-deficient ESCs. Black-Right-Pointing-Pointer miR-320 targets p57 and helps to release Dgcr8-deficient ESCs from G1 arrest. Black-Right-Pointing-Pointer miR-702 targets p21 and helps to release Dgcr8-deficient ESCs from G1 arrest. -- Abstract: MicroRNAs are known to contribute significantly to stem cell phenotype by post-transcriptionally regulating gene expression. Most of our knowledge of microRNAs comes from the study of canonical microRNAs that require two sequential cleavages by the Drosha/Dgcr8 heterodimer and Dicer to generate mature products. In contrast, non-canonical microRNAs bypass the cleavage by the Drosha/Dgcr8 heterodimer within the nucleus but still require cytoplasmic cleavage by Dicer. The function of non-canonical microRNAs in embryonic stem cells (ESCs) remains obscure. It has been hypothesized that non-canonical microRNAs have important roles in ESCs based upon the phenotypes of ESC lines that lack these specific classes of microRNAs; Dicer-deficient ESCs lacking both canonical and non-canonical microRNAs have much more severe proliferation defect than Dgcr8-deficient ESCs lacking only canonical microRNAs. Using these cell lines, we identified two non-canonical microRNAs, miR-320 and miR-702, that promote proliferation of Dgcr8-deficient ESCs by releasing them from G1 arrest. This is accomplished by targeting the 3 Prime -untranslated regions of the cell cycle inhibitors p57 and p21 and thereby inhibiting their expression. This is the first report of the crucial role of non-canonical microRNAs in ESCs.

  8. Superfund Record of Decision (Region 2): Love Canal/93rd Street, New York (third remedial action), September 1988

    SciTech Connect (OSTI)

    Not Available

    1988-09-26

    The Love Canal/93rd Street School site consists of approximately 19 acres and includes a school and an adjacent vacant lot. The site is located in Niagara Falls, New York, less than one mile northwest of Love Canal and is within the Love Canal Emergency Declaration Area. Hooker Chemicals and Plastics Corporation disposed of over 21,000 tons of various chemicals at the Love Canal site from 1942 to 1953, when the site was deeded over to the City of Niagara Falls Board of Education. Sampling has revealed that approximately 6,000 cu yds of soil are contaminated. During the 1950s, home construction accelerated in the area. Specifically, in 1950, the 93rd Street School was built, and in 1954, the 99th Street School was built adjacent to the middle portion of the Canal. Prior to construction of the 93rd Street School, a drainage swale crossed the site. Between 1938 and 1951, the swale was partially filled with soil and rock debris, followed by sand and fly ash materials. In 1980, the 93rd Street School was closed due to public health concerns related to the potentially contaminated fill material. The primary contaminants of concern affecting soil are VOCs, including toluene and xylenes, other organics including dioxins, PAHs and pesticides, and metals including arsenic and lead.

  9. miR-182 targets CHL1 and controls tumor growth and invasion in papillary thyroid carcinoma

    SciTech Connect (OSTI)

    Zhu, Hongling; Fang, Jin; Zhang, Jichen; Zhao, Zefei; Liu, Lianyong; Wang, Jingnan; Xi, Qian; Gu, Mingjun

    2014-07-18

    Highlights: miR-182 and CHL1 expression patterns are negatively correlated. CHL1 is a direct target of miR-182 in PTC cells. miR-182 suppression inhibits PTC cell growth and invasion. CHL1 is involved in miR-182-mediated cell behavior. - Abstract: In this study, we investigated the role and underlying mechanism of action of miR-182 in papillary thyroid carcinoma (PTC). Bioinformatics analysis revealed close homolog of LI (CHL1) as a potential target of miR-182. Upregulation of miR-182 was significantly correlated with CHL1 downregulation in human PTC tissues and cell lines. miR-182 suppressed the expression of CHL1 mRNA through direct targeting of the 3?-untranslated region (3?-UTR). Downregulation of miR-182 suppressed growth and invasion of PTC cells. Silencing of CHL1 counteracted the effects of miR-182 suppression, while its overexpression mimicked these effects. Our data collectively indicate that miR-182 in PTC promotes cell proliferation and invasion through direct suppression of CHL1, supporting the potential utility of miR-182 inhibition as a novel therapeutic strategy against PTC.

  10. Building America Case Study: Conway Street Apartments, Greenfield, Massachusetts (Fact Sheet), Whole-House Solutions for Existing Homes, Energy Efficiency & Renewable Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Conway Street Apartments Greenfield, Massachusetts PROJECT INFORMATION Project Name: Conway Street Apartments: A Multifamily Deep Energy Retrofit Location: Greenfield, MA Construction: Multifamily (gut rehabili- tation of a vacant school building) Type: Rental apartments Partners: Olive Street Development, zaccheoproperties.com Consortium for Advanced Residential Buildings, carb-swa.com Size: 12 apartments; 1-2 bedroom, 500-1,100 ft 2 Price Range: $900-$1,600/month Date completed: 2014 Climate

  11. miR-128 and its target genes in tumorigenesis and metastasis

    SciTech Connect (OSTI)

    Li, Molin, E-mail: molin_li@hotmail.com [Dalian Medical University, Dalian 116044 (China); Fu, Weiming [Center for Food Safety and Environmental Technology, Guangzhou Institute of Advanced Technology, Chinese Academy of Sciences, Guangzhou 511458 (China); Wo, Lulu; Shu, Xiaohong [Dalian Medical University, Dalian 116044 (China); Liu, Fang [The second affiliated hospital of Dalian Medical University, Dalian 116023 (China); Li, Chuangang, E-mail: li_chuangang@sina.com [The second affiliated hospital of Dalian Medical University, Dalian 116023 (China)

    2013-12-10

    MicroRNAs (miRNAs) are a class of endogenous, non-coding, 1824 nucleotide length single-strand RNAs that could modulate gene expression at post-transcriptional level. Previous studies have shown that miR-128 enriched in the brain plays an important role in the development of nervous system and the maintenance of normal physical functions. Aberrant expression of miR-128 has been detected in many types of human tumors and its validated target genes are involved in cancer-related biological processes such as cell proliferation, differentiation and apoptosis. In this review, we will summarize the roles of miR-128 and its target genes in tumorigenesis and metastasis. - Highlights: Aberrant expression of miR-128 can be observed in many kinds of malignant tumors. The molecular mechanisms regulating miR-128 expression are elucidated. Roles of miR-128 and its target genes in tumorigenesis and metastasis are summarized.

  12. DOE Zero Energy Ready Home Case Study: Cobblestone Homes, Midland, MI |

    Energy Savers [EERE]

    Department of Energy Cobblestone Homes, Midland, MI DOE Zero Energy Ready Home Case Study: Cobblestone Homes, Midland, MI Case study of a DOE Zero Energy Ready home in Midland, MI, that scored HERS 49 without PV or HERS 44 with 1.4 kW of PV. The custom home served as a prototype and energy efficiency demonstration model while performance testing was conducted. The 2-story, 2,745-ft2 home has 2.5 inches of closed-cell spray foam in the 2x4 wall cavities, plus 1-inch of rigid exterior foam; a

  13. MOLTEN CARBONATE FUEL CELL POWER PLANT LOCATED AT LADWP MAIN STREET SERVICE CENTER

    SciTech Connect (OSTI)

    William W. Glauz

    2004-09-10

    The Los Angeles Department of Water and Power (LADWP) has developed one of the most recognized fuel cell demonstration programs in the United States. In addition to their high efficiencies and superior environmental performance, fuel cells and other generating technologies that can be located at or near the load, offers several electric utility benefits. Fuel cells can help further reduce costs by reducing peak electricity demand, thereby deferring or avoiding expenses for additional electric utility infrastructure. By locating generators near the load, higher reliability of service is possible and the losses that occur during delivery of electricity from remote generators are avoided. The potential to use renewable and locally available fuels, such as landfill or sewage treatment waste gases, provides another attractive outlook. In Los Angeles, there are also many oil producing areas where the gas by-product can be utilized. In June 2000, the LADWP contracted with FCE to install and commission the precommercial 250kW MCFC power plant. The plant was delivered, installed, and began power production at the JFB in August 2001. The plant underwent manufacturer's field trials up for 18 months and was replace with a commercial plant in January 2003. In January 2001, the LADWP contracted with FCE to provide two additional 250kW MCFC power plants. These commercial plants began operations during mid-2003. The locations of these plants are at the Terminal Island Sewage Treatment Plant at the Los Angeles Harbor (for eventual operation on digester gas) and at the LADWP Main Street Service Center east of downtown Los Angeles. All three carbonate fuel cell plants received partial funding through the Department of Defense's Climate Change Fuel Cell Buydown Program. This report covers the technical evaluation and benefit-cost evaluation of the Main Street 250kW MCFC power plant during its first year of operation from September 2003 to August 2004. The data for the month of September 2004 was not available at the time this report was prepared. An addendum to this report will be prepared and transmitted to the Department of Energy once this data becomes available. This fuel cell power plant was originally intended to be installed at an American Airlines facility located at Los Angeles International Airport, however, due to difficulties in obtaining a site, the plant was ultimately installed at the LADWP's Distributed Generation Test Facility at it's Main Street Service Center.

  14. Addressing Biomass Supply Chain Challenges With AFEX(tm) Technology |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Addressing Biomass Supply Chain Challenges With AFEX(tm) Technology Addressing Biomass Supply Chain Challenges With AFEX(tm) Technology Plenary IV: Advances in Bioenergy Feedstocks-From Field to Fuel Addressing Biomass Supply Chain Challenges With AFEX(tm) Technology Allen Julian, Chief Business Officer, MBI PDF icon julian_biomass_2014.pdf More Documents & Publications 2015 Peer Review Presentations-Biochemical Conversion Process Design and Economics for Biochemical

  15. Secretary Chu Addresses the International Atomic Energy Agency General

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Conference | Department of Energy Addresses the International Atomic Energy Agency General Conference Secretary Chu Addresses the International Atomic Energy Agency General Conference September 20, 2010 - 12:00am Addthis Washington, DC - U.S. Energy Secretary Steven Chu addressed the International Atomic Energy Agency's 54th General Conference today in Vienna. His prepared remarks are below: Thank you, Ambassador Enkhsaikhan. Congratulations on your election as President of this Conference.

  16. Secretary Moniz Addresses Conference on the Caribbean's Energy Future |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Secretary Moniz Addresses Conference on the Caribbean's Energy Future Secretary Moniz Addresses Conference on the Caribbean's Energy Future December 6, 2013 - 2:42pm Addthis Secretary Moniz Addresses Conference on the Caribbean’s Energy Future Secretary Moniz joined Inter-American Development Bank President Luis Alberto Moreno in welcoming a group of Caribbean ministers who convened to discuss the region's energy future, climate change, and the roles of energy

  17. Energy Department Assistant Secretary Patricia Hoffman Addresses 2011 FERC

    Energy Savers [EERE]

    Reliability Technical Conference | Department of Energy Patricia Hoffman Addresses 2011 FERC Reliability Technical Conference Energy Department Assistant Secretary Patricia Hoffman Addresses 2011 FERC Reliability Technical Conference November 30, 2011 - 1:50pm Addthis WASHINGTON, D.C. - Department of Energy Assistant Secretary for Electricity Delivery and Energy Reliability Patricia Hoffman today addressed the 2011 Federal Energy Regulatory Commission technical conference in Washington, D.C.

  18. Department of Energy Releases Strategic Plan to Address Energy Challenges |

    Energy Savers [EERE]

    Department of Energy Strategic Plan to Address Energy Challenges Department of Energy Releases Strategic Plan to Address Energy Challenges October 2, 2006 - 9:01am Addthis WASHINGTON, DC - Secretary of Energy Samuel W. Bodman today released the Department's five-year strategic plan that focuses on the Department's role in powering and securing America's future. The plan addresses overall Department goals for developing and deploying new clean energy technologies, reducing our dependence on

  19. DOE Seeks Input On Addressing Contractor Pension and Medical Benefits

    Energy Savers [EERE]

    Liabilities | Department of Energy Input On Addressing Contractor Pension and Medical Benefits Liabilities DOE Seeks Input On Addressing Contractor Pension and Medical Benefits Liabilities March 27, 2007 - 12:10pm Addthis WASHINGTON, DC - The U.S. Department of Energy (DOE) today announced in the Federal Register that it is seeking public comment on how to address the increasing costs and liabilities of contractor employee pension and medical benefits. Under the Department of Energy's unique

  20. Steffes Corporation Smart Grid RFI: Addressing Policy and Logistical

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Challenges | Department of Energy Steffes Corporation Smart Grid RFI: Addressing Policy and Logistical Challenges Steffes Corporation Smart Grid RFI: Addressing Policy and Logistical Challenges Steffes Corporation Smart Grid RFI: Addressing Policy and Logistical Challenges. The Department of Energy is seeking comments on policy and logistical challenges that confront smart grid implementation, as well as recommendations on how to best overcome those challenges. PDF icon Steffes Corporation

  1. U.S. Leads International Collaborative to Address Wind Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Development/Wildlife Challenges | Department of Energy Leads International Collaborative to Address Wind Energy Development/Wildlife Challenges U.S. Leads International Collaborative to Address Wind Energy Development/Wildlife Challenges May 18, 2015 - 5:46pm Addthis The U.S. Department of Energy (DOE) is leading a new International Energy Agency (IEA) Wind Task to address concerns about the environmental effects of wind energy technology. Task 34, also known as WREN (Working together to

  2. Executive Order 12898: Federal Actions to Address Environmental Justice in

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Minority Populations and Low-Income Populations (1994) | Department of Energy 2898: Federal Actions to Address Environmental Justice in Minority Populations and Low-Income Populations (1994) Executive Order 12898: Federal Actions to Address Environmental Justice in Minority Populations and Low-Income Populations (1994) Executive Order 12898: Federal Actions to Address Environmental Justice in Minority Populations and Low-Income Populations (1994). Directs each federal agency to make

  3. Strategies to Address Split Incentives in Multifamily Buildings |

    Energy Savers [EERE]

    Department of Energy Strategies to Address Split Incentives in Multifamily Buildings Strategies to Address Split Incentives in Multifamily Buildings Better Buildings Neighborhood Program Multifamily / Low-Income Peer Exchange Call: Strategies to Address Split Incentives in Multifamily Buildings, Call Slides and Discussion Summary, April 26, 2012. PDF icon Call Slides and Discussion Summary More Documents & Publications Outreach to Multifamily Landlords and Tenants Stewards of Affordable

  4. Abraham Calls on Global Community to Aggressively Address Nuclear

    Energy Savers [EERE]

    Nonproliferation | Department of Energy Abraham Calls on Global Community to Aggressively Address Nuclear Nonproliferation Abraham Calls on Global Community to Aggressively Address Nuclear Nonproliferation January 13, 2005 - 9:49am Addthis WASHINGTON, DC - In a lunchtime speech to the Council on Foreign Relations in Washington, DC, Energy Secretary Spencer Abraham called on the global community to join in implementing a comprehensive nuclear nonproliferation strategy to address 21st century

  5. Bush Administration Plays Leading Role in Studying and Addressing Global

    Energy Savers [EERE]

    Climate Change | Department of Energy Plays Leading Role in Studying and Addressing Global Climate Change Bush Administration Plays Leading Role in Studying and Addressing Global Climate Change February 27, 2007 - 3:49pm Addthis Washington, DC - Continuing to take the lead in addressing global climate change, Energy Secretary Samuel Bodman, Environmental Protection Agency (EPA) Administrator Stephen Johnson, and National Oceanic and Atmospheric Administration (NOAA) Administrator Vice

  6. Energy-Intensive Processes Portfolio: Addressing Key Energy Challenges

    Office of Environmental Management (EM)

    Across U.S. Industry | Department of Energy Energy-Intensive Processes Portfolio: Addressing Key Energy Challenges Across U.S. Industry Energy-Intensive Processes Portfolio: Addressing Key Energy Challenges Across U.S. Industry PDF icon eip_report_pg9.pdf More Documents & Publications ITP Energy Intensive Processes: Energy-Intensive Processes Portfolio: Addressing Key Energy Challenges Across U.S. Industry Energy Technology Solutions Energy Technology Solutions: Public-Private

  7. Expanding Opportunity and Addressing Unique Challenges Facing Women and

    Office of Environmental Management (EM)

    Girls of Color | Department of Energy Expanding Opportunity and Addressing Unique Challenges Facing Women and Girls of Color Expanding Opportunity and Addressing Unique Challenges Facing Women and Girls of Color November 17, 2014 - 11:35am Addthis When President Obama founded the White House Council on Women and Girls (CWG) within the first two months of taking office, he charged us with working to address inequalities and barriers facing women and girls in our schools, workplaces, and

  8. Energy Saver RSS Subscribers: Update Your Feed Address | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Saver RSS Subscribers: Update Your Feed Address Energy Saver RSS Subscribers: Update Your Feed Address September 28, 2015 - 12:46pm Addthis Just a short administrative note for Energy Saver RSS subscribers: our feed address is changing. To continue reading the Energy Saver Blog through your RSS feed reader, please update the link in your reader to http://energy.gov/rss/energysaver/1280681. Thanks for reading and subscribing to Energy Saver! Addthis Related Articles The Energy Savers

  9. Headquarters Program & Staff Office Mailing Addresses | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Headquarters Program & Staff Office Mailing Addresses Headquarters Program & Staff Office Mailing Addresses The following addresses are for delivery of regular mail and small packages: Delivery to the Headquarters buildings in Washington, DC: Name of Individual Title Routing Symbol/Forrestal Building U.S. Department of Energy 1000 Independence Ave., S.W. Washington, DC 20585 Name of Individual Title Routing Symbol/L'Enfant Plaza Building U.S. Department of Energy 1000

  10. EPA -- Addressing Children's Health through Reviews Conducted Pursuant to

    Office of Environmental Management (EM)

    the National Environmental Policy Act and Section 309 of the Clean Air Act | Department of Energy Addressing Children's Health through Reviews Conducted Pursuant to the National Environmental Policy Act and Section 309 of the Clean Air Act EPA -- Addressing Children's Health through Reviews Conducted Pursuant to the National Environmental Policy Act and Section 309 of the Clean Air Act Addressing Children's Health through Reviews Conducted Pursuant to the National Environmental Policy Act

  11. Advanced Test Reactor National Scientific User Facility: Addressing...

    Office of Scientific and Technical Information (OSTI)

    Advanced Test Reactor National Scientific User Facility: Addressing advanced nuclear materials research Citation Details In-Document Search Title: Advanced Test Reactor National ...

  12. Energy Department Addresses Largest Gathering of Geothermal Energy...

    Broader source: Energy.gov (indexed) [DOE]

    Resources Council (GRC) in Reno, Nevada-the industry's largest annual gathering of geothermal energy stakeholders in the nation. In his keynote address, Hollett discussed...

  13. Advanced Test Reactor National Scientific User Facility: Addressing...

    Office of Scientific and Technical Information (OSTI)

    Advanced Test Reactor National Scientific User Facility: Addressing advanced nuclear materials research Citation Details In-Document Search Title: Advanced Test Reactor National...

  14. Address (Smart Grid Project) (France) | Open Energy Information

    Open Energy Info (EERE)

    France) Jump to: navigation, search Project Name Address Country France Coordinates 46.073231, 2.427979 Loading map... "minzoom":false,"mappingservice":"googlemaps3","type":"R...

  15. Smart Grid RFI: Addressing Policy and Logistical Challenges,...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Challenges, Comments from the Edison Electric Institute Smart Grid RFI: Addressing Policy and Logistical Challenges, Comments from the Edison Electric Institute The Edison Electric ...

  16. Smart Grid RFI: Addressing Policy and Logistical Challenges....

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Challenges. Comments of the Alliance to Save Energy. Smart Grid RFI: Addressing Policy and Logistical Challenges. Comments of the Alliance to Save Energy. The Alliance to Save ...

  17. Microsoft Word - Actions to address lessons learned.doc

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Actions to address Work Planning and Scheduling System lessons learned Action Executive owner Staff assigned Due date Understand the business environment of vendor references....

  18. Dairyland Power Cooperative Comments on Smart Grid RFI: Addressing...

    Broader source: Energy.gov (indexed) [DOE]

    National Consumer Law Center, and Public Citizen Comments to:DEPARTMENT OF ENERGY Smart Grid RFI: Addressing Policy and Logistical Challenges Florida Power and Light Comments on...

  19. Africa - Technical Potential of Solar Energy to Address Energy...

    Open Energy Info (EERE)

    - Technical Potential of Solar Energy to Address Energy Poverty and Avoid GHG Emissions Jump to: navigation, search Tool Summary LAUNCH TOOL Name: Technical Potential of Solar...

  20. New partnership uses advanced computer science modeling to address...

    National Nuclear Security Administration (NNSA)

    partnership uses advanced computer science modeling to address climate change | National Nuclear Security Administration Facebook Twitter Youtube Flickr RSS People Mission Managing...

  1. Ames Laboratory to Lead New Research Effort to Address Shortages...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Laboratory to Lead New Research Effort to Address Shortages in Rare Earth and Other Critical Materials Ames Laboratory ... electric vehicles, advanced batteries and a host of ...

  2. Exploring the Utilization of Complex Algal Communities to Address...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Exploring the Utilization of Complex Algal Communities to Address Algal Pond Crash and Increase Annual Biomass Production for Algal Biofuels Exploring the Utilization of Complex...

  3. Pensacola Smart Grid RFI Addressing Policy and Logistical Challenges...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Pensacola Smart Grid RFI Addressing Policy and Logistical Challenges. Providing comment on: Consumer facing programs such as feedback, demandresponse, energy efficiency, and ...

  4. Natural Gas Industry Comments on Smart Grid RFI: Addressing Policy...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Electricity Delivery and Energy Reliability's Request for Information Addressing Policy and Logistical Challenges to Smart Grid Implementation, 75 Fed. Reg. 57,006 (Sep. 17, 2010). ...

  5. Addressing Policy and Logistical Challenges to Smart Grid Implementati...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Smart Grid Implementation: Comments by the Office of the Ohio Consumers' Counsel Addressing Policy and Logistical Challenges to Smart Grid Implementation: Comments by the Office of ...

  6. Addressing Policy and Logistical Challenges to Smart Grid Implementati...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Smart Grid Implementation: Federal Register Notice Volume 75, No. 180 - Sep. 17, 2010 Addressing Policy and Logistical Challenges to Smart Grid Implementation: Federal Register ...

  7. Ambient Corporation's Reply comments to DOE RFI: Addressing Policy...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Ambient Corporation's Reply comments to DOE RFI: Addressing Policy and Logistical Challenges to Smart Grid Implementation Ambient Corporation's Reply comments to DOE RFI: ...

  8. Addressing the Voltage Fade Issue with Lithium-Manganese-Rich...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Voltage Fade Issue with Lithium-Manganese-Rich Oxide Cathode Materials Addressing the Voltage Fade Issue with Lithium-Manganese-Rich Oxide Cathode Materials 2012 DOE Hydrogen and...

  9. File:USDA-CE-Production-GIFmaps-MI.pdf | Open Energy Information

    Open Energy Info (EERE)

    MI.pdf Jump to: navigation, search File File history File usage Michigan Ethanol Plant Locations Size of this preview: 463 599 pixels. Other resolution: 464 600 pixels. Full...

  10. Climate Action Champions: Sault Ste. Marie Tribe of Chippewa Indians, MI |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Sault Ste. Marie Tribe of Chippewa Indians, MI Climate Action Champions: Sault Ste. Marie Tribe of Chippewa Indians, MI The Sault Ste. Marie Tribe of Chippewa Indians is a 44,000-strong federally recognized Indian tribe that is an economic, social and cultural force in its community across the eastern Upper Peninsula counties of Chippewa, Luce, Mackinac, Schoolcraft, Alger, Delta and Marquette, with housing and tribal centers, casinos, and other enterprises that employ

  11. Keynote Address: Ali Zaidi, the White House Domestic Policy Council |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Ali Zaidi, the White House Domestic Policy Council Keynote Address: Ali Zaidi, the White House Domestic Policy Council May 21, 2014 2:05PM to 2:30PM PDT Pacific Ballroom Keynote address by Ali Zaidi, Deputy Director for Energy Policy, the White House Domestic Policy Council

  12. Method for the electro-addressable functionalization of electrode arrays

    DOE Patents [OSTI]

    Harper, Jason C.; Polsky, Ronen; Dirk, Shawn M.; Wheeler, David R.; Arango, Dulce C.; Brozik, Susan M.

    2015-12-15

    A method for preparing an electrochemical biosensor uses bias-assisted assembly of unreactive -onium molecules on an electrode array followed by post-assembly electro-addressable conversion of the unreactive group to a chemical or biological recognition group. Electro-addressable functionalization of electrode arrays enables the multi-target electrochemical sensing of biological and chemical analytes.

  13. Symbiosis: Addressing Biomass Production Challenges and Climate Change |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Symbiosis: Addressing Biomass Production Challenges and Climate Change Symbiosis: Addressing Biomass Production Challenges and Climate Change This presentation was the opening keynote of the Symbiosis Conference. PDF icon symbiosis_conference_hamilton.pdf More Documents & Publications The Future of Bioenergy Feedstock Production Symbiosis Biofeedstock Conference: Expanding Commercialization of Mutualistic Microbes to Increase Feedstock Production Symbiosis

  14. IP address management : augmenting Sandia's capabilities through open source tools.

    SciTech Connect (OSTI)

    Nayar, R. Daniel

    2005-08-01

    Internet Protocol (IP) address management is an increasingly growing concern at Sandia National Laboratories (SNL) and the networking community as a whole. The current state of the available IP addresses indicates that they are nearly exhausted. Currently SNL doesn't have the justification to obtain more IP address space from Internet Assigned Numbers Authority (IANA). There must exist a local entity to manage and allocate IP assignments efficiently. Ongoing efforts at Sandia have been in the form of a multifunctional database application notably known as Network Information System (NWIS). NWIS is a database responsible for a multitude of network administrative services including IP address management. This study will explore the feasibility of augmenting NWIS's IP management capabilities utilizing open source tools. Modifications of existing capabilities to better allocate available IP address space are studied.

  15. miR-196a targets netrin 4 and regulates cell proliferation and migration of cervical cancer cells

    SciTech Connect (OSTI)

    Zhang, Jie; Zheng, Fangxia; Yu, Gang; Yin, Yanhua; Lu, Qingyang

    2013-11-01

    Highlights: miR-196a was overexpressed in cervical cancer tissue compared to normal tissue. miR-196a expression elevated proliferation and migration of cervical cancer cells. miR-196a inhibited NTN4 expression by binding 3?-UTR region of NTN4 mRNA. NTN4 inversely correlated with miR-196a expression in cervical tissue and cell line. NTN4 expression was low in cervical cancer tissue compared to normal tissue. -- Abstract: Recent research has uncovered tumor-suppressive and oncogenic potential of miR-196a in various tumors. However, the expression and mechanism of its function in cervical cancer remains unclear. In this study, we assess relative expression of miR-196a in cervical premalignant lesions, cervical cancer tissues, and four cancer cell lines using quantitative real-time PCR. CaSki and HeLa cells were treated with miR-196a inhibitors, mimics, or pCDNA/miR-196a to investigate the role of miR-196a in cancer cell proliferation and migration. We demonstrated that miR-196a was overexpressed in cervical intraepithelial neoplasia 23 and cervical cancer tissue. Moreover, its expression contributes to the proliferation and migration of cervical cancer cells, whereas inhibiting its expression led to a reduction in proliferation and migration. Five candidate targets of miR-196a chosen by computational prediction and Cervical Cancer Gene Database search were measured for their mRNA in both miR-196a-overexpressing and -depleted cancer cells. Only netrin 4 (NTN4) expression displayed an inverse association with miR-196a. Fluorescent reporter assays revealed that miR-196a inhibited NTN4 expression by targeting one binding site in the 3?-untranslated region (3?-UTR) of NTN4 mRNA. Furthermore, qPCR and Western blot assays verified NTN4 expression was downregulated in cervical cancer tissues compared to normal controls, and in vivo mRNA level of NTN4 inversely correlated with miR-196a expression. In summary, our findings provide new insights about the functional role of miR-196a in cervical carcinogenesis and suggested a potential use of miR-196a for clinical diagnosis and as a therapeutic target.

  16. The INL Seismic Risk Assessment Project: Requirements for Addressing DOE

    Office of Environmental Management (EM)

    Order 420.1C & A Proposed Generic Methodology | Department of Energy The INL Seismic Risk Assessment Project: Requirements for Addressing DOE Order 420.1C & A Proposed Generic Methodology The INL Seismic Risk Assessment Project: Requirements for Addressing DOE Order 420.1C & A Proposed Generic Methodology Presentation from the May 2015 Seismic Lessons-Learned Panel Meeting. PDF icon The INL Seismic Risk Assessment Project: Requirements for Addressing DOE Order 420.1C & A

  17. Keynote Address: Cristin Dorgelo, White House Office of Science...

    Broader source: Energy.gov (indexed) [DOE]

    to 2:30PM PDT Pacific Ballroom Cristin Dorgelo, Assistant Director of Grand Challenges for The White House Office of Science and Technology Policy will deliver a keynote address...

  18. United Indigenous Voices Address Sustainability: Climate Change and Traditional Places

    Broader source: Energy.gov [DOE]

    At the First Stewards Symposium, over 300 industry and policy leaders from around the nation will discuss four main themes generated from the 2012 First Stewards Symposium that address issues...

  19. Pepco Holdings, Inc. Smart Grid RFI: Addressing Policy and Logistical...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    This follows on the heels of PHI's responses to two other DOE RFls on data access and ... More Documents & Publications DC OPC Comments. September 17, 2010 Addressing Policy and ...

  20. Keynote Address: Ali Zaidi, the White House Domestic Policy Council...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Ali Zaidi, the White House Domestic Policy Council Keynote Address: Ali Zaidi, the White House Domestic Policy Council May 21, 2014 2:05PM to 2:30PM PDT Pacific Ballroom Keynote...

  1. Financing Innovation to Address Global Climate Change | Department of

    Broader source: Energy.gov (indexed) [DOE]

    Energy DOE-LPO_Report_Financing-Innovation-Climate-Change.pdf More Documents & Publications LPO Financial Performance Report PORTFOLIO PERFORMANCE Financing Innovation to Address Global Climate Change Powering New Markets: Utility-scale Photovoltaic Solar

  2. The State of the Ames Laboratory Address 2011

    ScienceCinema (OSTI)

    King, Alex

    2013-03-01

    Alex King, director of The Ames Laboratory, discusses the budget situation, improvements at Ames Lab and infrastructure improvements during the State of the Lab address on Tuesday, May 24, 2011.

  3. Corrective Action Plan Addressing the Accident Investigation Report

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Corrective Action Plan Addressing the Accident Investigation Report of the February 5, 2014 Fire Event and the February 14, 2014 Radiological Release Event, Rev 1 Page 2 of 89 Table of Contents 1 Purpose ................................................................................................................................................................................................ 7 2 Summary of the

  4. Addressing Policy and Logistical Challenges to smart grid Implementati...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Addressing Policy and Logistical Challenges to smart grid Implementation: eMeter Response to Department of Energy RFI eMeter is a smart grid software company that provides smart ...

  5. NERSC Implements Organizational Changes to Better Address Evolving Data

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Environment NERSC Organizational Changes to Better Address Evolving Data Environment NERSC Implements Organizational Changes to Better Address Evolving Data Environment February 23, 2015 Contact: Jon Bashor, jbashor@lbl.gov, 510-486-5849 Sudip Dosanjh, director of the Department of Energy's National Energy Research Scientific Computing Center, announced several organizational changes to help the center's 6,000 users more productively manage their data-intensive research. The changes took

  6. Exploring the Utilization of Complex Algal Communities to Address Algal

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Pond Crash and Increase Annual Biomass Production for Algal Biofuels | Department of Energy Exploring the Utilization of Complex Algal Communities to Address Algal Pond Crash and Increase Annual Biomass Production for Algal Biofuels Exploring the Utilization of Complex Algal Communities to Address Algal Pond Crash and Increase Annual Biomass Production for Algal Biofuels white paper exploring complex algal communities as a means of increasing algal biomass production PDF icon

  7. Protocol for Addressing Induced Seismicity Associated with Enhanced

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Geothermal Systems (EGS) | Department of Energy Protocol for Addressing Induced Seismicity Associated with Enhanced Geothermal Systems (EGS) Protocol for Addressing Induced Seismicity Associated with Enhanced Geothermal Systems (EGS) This document is intended to assist industry and regulators identify important issues and parameters that may be necessary for the evaluation and mitigation of adverse effects of induced seismicity. PDF icon egs-is-protocol-final-draft-20110531.pdf More

  8. Protocol for Addressing Induced Seismicity Associated with Enhanced Geothermal Systems

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Protocol for Addressing Induced Seismicity Associated with Enhanced Geothermal Systems by Ernie Majer, James Nelson, Ann Robertson-Tait, Jean Savy, and Ivan Wong January 2012 | DOE/EE-0662 Cover Image Courtesy of Katie L. Boyle, Lawrence Berkeley National Laboratory i i Protocol for Addressing Induced Seismicity Associated with Enhanced Geothermal Systems Preface In June 2009, the New York Times published an article about the public fear of geothermal development causing earthquakes. The article

  9. Research Projects to Address Technical Challenges Facing Small Oil and

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Natural Gas Producers Selected by DOE for Further Development | Department of Energy to Address Technical Challenges Facing Small Oil and Natural Gas Producers Selected by DOE for Further Development Research Projects to Address Technical Challenges Facing Small Oil and Natural Gas Producers Selected by DOE for Further Development June 20, 2012 - 1:00pm Addthis Washington, DC - Nine new research projects aimed at extending the life of mature oil and natural gas fields, while simultaneously

  10. Helping Local Officials Address Fuel Shortages | Department of Energy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Helping Local Officials Address Fuel Shortages Helping Local Officials Address Fuel Shortages November 3, 2012 - 6:30pm Addthis The Energy Department continues to work with its federal and state partners to restore critical energy infrastructure throughout the region affected by Hurricane Sandy. The Energy Department continues to work with its federal and state partners to restore critical energy infrastructure throughout the region affected by Hurricane Sandy. Lindsey Geisler Lindsey Geisler

  11. PROJECT PROFILE: Addressing Soiling: From Interface Chemistry to

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Practicality | Department of Energy Addressing Soiling: From Interface Chemistry to Practicality PROJECT PROFILE: Addressing Soiling: From Interface Chemistry to Practicality Funding Opportunity: SuNLaMP SunShot Subprogram: Photovoltaics Location: National Renewable Energy Laboratory, Golden, CO Amount Awarded: $6,000,000 Natural soiling is responsible for about 4% output power loss and may be adding one cent per kilowatt hour to the levelized cost of energy (LCOE) depending on the site.

  12. Keynote Address: Cristin Dorgelo, White House Office of Science and

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Technology Policy | Department of Energy Cristin Dorgelo, White House Office of Science and Technology Policy Keynote Address: Cristin Dorgelo, White House Office of Science and Technology Policy May 21, 2014 2:20PM to 2:30PM PDT Pacific Ballroom Cristin Dorgelo, Assistant Director of Grand Challenges for The White House Office of Science and Technology Policy will deliver a keynote address

  13. Addressable morphology control of silica structures by manipulating the

    Office of Scientific and Technical Information (OSTI)

    reagent addition time (Journal Article) | SciTech Connect Addressable morphology control of silica structures by manipulating the reagent addition time Citation Details In-Document Search Title: Addressable morphology control of silica structures by manipulating the reagent addition time Authors: Sharma, Jaswinder K [1] ; Datskos, Panos G [1] ; Chen, Jihua [1] + Show Author Affiliations ORNL [ORNL Publication Date: 2014-01-01 OSTI Identifier: 1110986 DOE Contract Number: DE-AC05-00OR22725

  14. Addressing mechanical reliability issues in Sandia MEMS devices.

    Office of Scientific and Technical Information (OSTI)

    (Conference) | SciTech Connect Addressing mechanical reliability issues in Sandia MEMS devices. Citation Details In-Document Search Title: Addressing mechanical reliability issues in Sandia MEMS devices. No abstract prepared. Authors: Tanner, Danelle Mary, 1952- [1] ; -) ; Buchheit, Thomas E. ; Boyce, Brad Lee ; Goods, Steven Howard + Show Author Affiliations (, Publication Date: 2005-02-01 OSTI Identifier: 897611 Report Number(s): SAND2005-0920C TRN: US200705%%131 DOE Contract Number:

  15. Advanced Test Reactor National Scientific User Facility: Addressing

    Office of Scientific and Technical Information (OSTI)

    advanced nuclear materials research (Conference) | SciTech Connect Advanced Test Reactor National Scientific User Facility: Addressing advanced nuclear materials research Citation Details In-Document Search Title: Advanced Test Reactor National Scientific User Facility: Addressing advanced nuclear materials research The Advanced Test Reactor National Scientific User Facility (ATR NSUF), based at the Idaho National Laboratory in the United States, is supporting Department of Energy and

  16. Addressing Failures in Exascale Computing (Technical Report) | SciTech

    Office of Scientific and Technical Information (OSTI)

    Connect Technical Report: Addressing Failures in Exascale Computing Citation Details In-Document Search Title: Addressing Failures in Exascale Computing Authors: Snir, M. ; Wisniewski, R. W. ; Abraham, J. A. ; Adve, S. V. ; Bagchi, S. ; Balaji, P. ; Belak, J. ; Bose, P. ; Cappello, F. ; Carlson, B. ; Chien, A. A. ; Coteus, P. ; Debardeleben, N. A. ; Diniz, P. ; Engelmann, C. ; Erez, M. ; Fazzari, S. ; Geist, A. ; Gupta, R. ; Johnson, F. more »; Krishnamoorthy, S. ; Leyffer, S. ; Liberty, D.

  17. Dairyland Power Cooperative Comments on Smart Grid RFI: Addressing Policy

    Energy Savers [EERE]

    and Logistical Challenges | Department of Energy Comments on Smart Grid RFI: Addressing Policy and Logistical Challenges Dairyland Power Cooperative Comments on Smart Grid RFI: Addressing Policy and Logistical Challenges Dairyland Power Cooperative is a generation and transmission cooperative (G&T) that provides the wholesale electrical requirements and other services for 25 electric distribution cooperatives and 16 municipal utilities in the Upper Midwest. PDF icon Smart Grid RFI:

  18. DOE Awards Over a Billion Supercomputing Hours to Address Scientific

    Energy Savers [EERE]

    Challenges | Department of Energy Over a Billion Supercomputing Hours to Address Scientific Challenges DOE Awards Over a Billion Supercomputing Hours to Address Scientific Challenges January 26, 2010 - 12:00am Addthis Washington, DC. - The U.S. Department of Energy announced today that approximately 1.6 billion supercomputing processor hours have been awarded to 69 cutting-edge research projects through the Innovative and Novel Computational Impact on Theory and Experiment (INCITE) program.

  19. Okaloosa Gas District Smart Grid RFI: Addressing Policy and Logistical

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Challenges to Smart Grid Implementation | Department of Energy Okaloosa Gas District Smart Grid RFI: Addressing Policy and Logistical Challenges to Smart Grid Implementation Okaloosa Gas District Smart Grid RFI: Addressing Policy and Logistical Challenges to Smart Grid Implementation Okaloosa Gas District (The District) an Independent Special District of the State of Florida is appreciative of the opportunity to submit for your consideration the following comments in response to the U.S.

  20. NAP Coalition Response to DOE RFI: Addressing Policy and Logistical

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Challenges to Smart Grid Implementation | Department of Energy NAP Coalition Response to DOE RFI: Addressing Policy and Logistical Challenges to Smart Grid Implementation NAP Coalition Response to DOE RFI: Addressing Policy and Logistical Challenges to Smart Grid Implementation The NAP Coalition is a "Coalition of Coalitions" that has been formed for the purpose of implementing the National Action Plan released by FERC in cooperation with DOE in June of 2010. Organizations working

  1. Biosurveillance panel to address essential science for public health

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Panel to address essential science for public health Biosurveillance panel to address essential science for public health A team of national experts across varied disciplines will be gathering Feb. 17 in Chicago, prepared to explore the most critical aspects of international disease awareness. February 17, 2014 Basil Swanson Basil Swanson Contact Nancy Ambrosiano Communications Office (505) 699-1149 Email "It is absolutely essential that nations are able to quickly detect and characterize a

  2. Can Cloud Computing Address the Scientific Computing Requirements for DOE

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Researchers? Well, Yes, No and Maybe Can Cloud Computing Address the Scientific Computing Requirements for DOE Researchers? Well, Yes, No and Maybe Can Cloud Computing Address the Scientific Computing Requirements for DOE Researchers? Well, Yes, No and Maybe January 30, 2012 Jon Bashor, Jbashor@lbl.gov, +1 510-486-5849 Magellan1.jpg Magellan at NERSC After a two-year study of the feasibility of cloud computing systems for meeting the ever-increasing computational needs of scientists,

  3. Towards Addressing Surface Effects in Ordinary Isotropic Peridynamic Models

    Office of Scientific and Technical Information (OSTI)

    Position Aware Linear Solid (PALS). (Conference) | SciTech Connect Towards Addressing Surface Effects in Ordinary Isotropic Peridynamic Models Position Aware Linear Solid (PALS). Citation Details In-Document Search Title: Towards Addressing Surface Effects in Ordinary Isotropic Peridynamic Models Position Aware Linear Solid (PALS). Abstract not provided. Authors: Mitchell, John Anthony ; Silling, Stewart Andrew Publication Date: 2013-12-01 OSTI Identifier: 1121945 Report Number(s):

  4. President Obama Praises NAMII in State of the Union Address

    Broader source: Energy.gov [DOE]

    In his 2013 State of the Union address, President Obama used the National Additive Manufacturing Institute (NAMII) as a model of the potential for innovation in manufacturing in the U.S. His address made it clear that his Administration is making the revitalization of the manufacturing sector a priority, stating that he plans to make the U.S. "a magnet for new jobs and manufacturing." He laid out a plan for spurring growth in manufacturing in the following statement:

  5. Students Innovate to Address Gas Shortages Following Hurricane Sandy |

    Energy Savers [EERE]

    Department of Energy Innovate to Address Gas Shortages Following Hurricane Sandy Students Innovate to Address Gas Shortages Following Hurricane Sandy November 9, 2012 - 3:43pm Addthis Franklin High School students working on their online map of gas and charging stations. | Photo courtesy Dayana Bustamante Franklin High School students working on their online map of gas and charging stations. | Photo courtesy Dayana Bustamante Ian Kalin Director of the Energy Data Initiative What are the key

  6. ASHRAE draft regarding Smart Grid RFI: Addressing Policy and Logistical

    Energy Savers [EERE]

    Challenges | Department of Energy ASHRAE draft regarding Smart Grid RFI: Addressing Policy and Logistical Challenges ASHRAE draft regarding Smart Grid RFI: Addressing Policy and Logistical Challenges The American Society of Heating, Refrigerating and Air-Conditioning Engineers Inc. (ASHRAE), founded in 1894, is an international organization of over 50,000 members. ASHRAE fulfills its mission of advancing heating, ventilation, air conditioning and refrigeration to serve humanity and promote a

  7. Ambient Corporation's Reply comments to DOE RFI: Addressing Policy and

    Energy Savers [EERE]

    Logistical Challenges to Smart Grid Implementation | Department of Energy Ambient Corporation's Reply comments to DOE RFI: Addressing Policy and Logistical Challenges to Smart Grid Implementation Ambient Corporation's Reply comments to DOE RFI: Addressing Policy and Logistical Challenges to Smart Grid Implementation Ambient Corporation submits the following comments to the US Department of Energy (DOE) in hopes that their contribution can highlight and further the understanding of the DOE on

  8. Moving Forward to Address Nuclear Waste Storage and Disposal | Department

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of Energy Moving Forward to Address Nuclear Waste Storage and Disposal Moving Forward to Address Nuclear Waste Storage and Disposal March 24, 2015 - 2:15pm Addthis Three trucks transport nuclear waste from the Savannah River Site in South Carolina. | Energy Department photo. Three trucks transport nuclear waste from the Savannah River Site in South Carolina. | Energy Department photo. John Kotek John Kotek Acting Assistant Secretary for the Office of Nuclear Energy Thirty years ago, our

  9. Protocol for Addressing Induced Seismicity Associated with Enhanced

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Geothermal Systems | Department of Energy Protocol for Addressing Induced Seismicity Associated with Enhanced Geothermal Systems Protocol for Addressing Induced Seismicity Associated with Enhanced Geothermal Systems This Protocol is a living guidance document for geothermal developers, public officials, regulators and the general public that provides a set of general guidelines detailing useful steps to evaluate and manage the effects of induced seismicity related to EGS projects. PDF icon

  10. NETL's Supercomputer Addresses Energy Issues on Two Fronts | Department of

    Office of Environmental Management (EM)

    Energy Supercomputer Addresses Energy Issues on Two Fronts NETL's Supercomputer Addresses Energy Issues on Two Fronts September 26, 2013 - 10:42am Addthis The visualization center for the SBEUC (Simulation Based Engineering User Center). Located at the Department’s National Energy Technology Laboratory in Morgantown, W. Va., the SBEUC will be powered by a high performance computer that will allow researchers to simulate phenomena that are difficult or impossible to probe experimentally.

  11. ADR Lunchtime Program: Addressing Unconscious Bias in the ADR Process |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Addressing Unconscious Bias in the ADR Process ADR Lunchtime Program: Addressing Unconscious Bias in the ADR Process This session focuses on strategies, issues, and insights into how unconscious bias impacts our perceptions, beliefs, and behaviors in today's workplace. Real-world case studies and current research are provided to increase awareness of the elements of the mediation/ADR process that may be impacted by biased communication and perception. The discussion

  12. miR-421 induces cell proliferation and apoptosis resistance in human nasopharyngeal carcinoma via downregulation of FOXO4

    SciTech Connect (OSTI)

    Chen, Liang; Department of Otolaryngology, Guangzhou General Hospital of PLA Guangzhou Command, Guangzhou 510010 ; Tang, Yanping; Wang, Jian; Yan, Zhongjie; Xu, Ruxiang

    2013-06-14

    Highlights: •miR-421 is upregulated in nasopharyngeal carcinoma. •miR-421 induces cell proliferation and apoptosis resistance. •FOXO4 is a direct and functional target of miR-421. -- Abstract: microRNAs have been demonstrated to play important roles in cancer development and progression. Hence, identifying functional microRNAs and better understanding of the underlying molecular mechanisms would provide new clues for the development of targeted cancer therapies. Herein, we reported that a microRNA, miR-421 played an oncogenic role in nasopharyngeal carcinoma. Upregulation of miR-421 induced, whereas inhibition of miR-421 repressed cell proliferation and apoptosis resistance. Furthermore, we found that upregulation of miR-421 inhibited forkhead box protein O4 (FOXO4) signaling pathway following downregulation of p21, p27, Bim and FASL expression by directly targeting FOXO4 3′UTR. Additionally, we demonstrated that FOXO4 expression is critical for miR-421-induced cell growth and apoptosis resistance. Taken together, our findings not only suggest that miR-421 promotes nasopharyngeal carcinoma cell proliferation and anti-apoptosis, but also uncover a novel regulatory mechanism for inactivation of FOXO4 in nasopharyngeal carcinoma.

  13. U.S. Army Corps of Engineers Buffalo District Office 1776 Niagara Street, Buffalo, New York, 14207

    Office of Legacy Management (LM)

    Army Corps of Engineers Buffalo District Office 1776 Niagara Street, Buffalo, New York, 14207 Explanation of Significant Differences for the Rattlesnake Creek Portion of the Ashland Sites Tonawanda, New York September 20, 2004 Formerly Utilized Sites Remedial Action Program Explanation of Significant Differences for the Rattlesnake Creek Portion of the Ashland Sites Table of Contents I. INTRODUCTION 1 II. SITE mSTORY, CONTAMINATION AND SELECTED REMEDy 2 A. Site History 2 B. Original Remedy 3

  14. Ionizing RadiationInducible miR-27b Suppresses Leukemia Proliferation via Targeting Cyclin A2

    SciTech Connect (OSTI)

    Wang, Bo; Li, Dongping; Kovalchuk, Anna; Litvinov, Dmitry; Kovalchuk, Olga

    2014-09-01

    Purpose: Ionizing radiation is a common carcinogen that is important for the development of leukemia. However, the underlying epigenetic mechanisms remain largely unknown. The goal of the study was to explore microRNAome alterations induced by ionizing radiation (IR) in murine thymus, and to determine the role of IR-inducible microRNA (miRNA/miR) in the development of leukemia. Methods and Materials: We used the well-established C57BL/6 mouse model and miRNA microarray profiling to identify miRNAs that are differentially expressed in murine thymus in response to irradiation. TIB152 human leukemia cell line was used to determine the role of estrogen receptor? (ER?) in miR-27b transcription. The biological effects of ectopic miR-27b on leukemogenesis were measured by western immunoblotting, cell viability, apoptosis, and cell cycle analyses. Results: Here, we have shown that IR triggers the differential expression of miR-27b in murine thymus tissue in a dose-, time- and sex-dependent manner. miR-27b was significantly down-regulated in leukemia cell lines CCL119 and TIB152. Interestingly, ER? was overexpressed in those 2cell lines, and it was inversely correlated with miR-27b expression. Therefore, we used TIB152 as a model system to determine the role of ER? in miR-27b expression and the contribution of miR-27b to leukemogenesis. ?-Estradiol caused a rapid and transient reduction in miR-27b expression reversed by either ER?-neutralizing antibody or ERK1/2 inhibitor. Ectopic expression of miR-27b remarkably suppressed TIB152cell proliferation, at least in part, by inducing S-phase arrest. In addition, it attenuated the expression of cyclin A2, although it had no effect on the levels of PCNA, PPAR?, CDK2, p21, p27, p-p53, and cleaved caspase-3. Conclusion: Our data reveal that ?-estradiol/ER? signaling may contribute to the down-regulation of miR-27b in acute leukemia cell lines through the ERK1/2 pathway, and that miR-27b may function as a tumor suppressor that inhibits cell proliferation by targeting cyclin A2.

  15. miR-339-5p inhibits alcohol-induced brain inflammation through regulating NF-κB pathway

    SciTech Connect (OSTI)

    Zhang, Yu; Wei, Guangkuan; Di, Zhiyong; Zhao, Qingjie

    2014-09-26

    Graphical abstract: - Highlights: • Alcohol upregulates miR-339-5p expression. • miR-339-5p inhibits the NF-kB pathway. • miR-339-5p interacts with and blocks activity of IKK-beat and IKK-epsilon. • miR-339-5p modulates IL-1β, IL-6 and TNF-α. - Abstract: Alcohol-induced neuroinflammation is mediated by the innate immunesystem. Pro-inflammatory responses to alcohol are modulated by miRNAs. The miRNA miR-339-5p has previously been found to be upregulated in alcohol-induced neuroinflammation. However, little has been elucidated on the regulatory functions of this miRNA in alcohol-induced neuroinflammation. We investigated the function of miR-339-5p in alcohol exposed brain tissue and isolated microglial cells using ex vivo and in vitro techniques. Our results show that alcohol induces transcription of miR 339-5p, IL-6, IL-1β and TNF-α in mouse brain tissue and isolated microglial cells by activating NF-κB. Alcohol activation of NF-κB allows for nuclear translocation of the NF-κB subunit p65 and expression of pro-inflammatory mediators. miR-339-5p inhibited expression of these pro-inflammatory factors through the NF-κB pathway by abolishing IKK-β and IKK-ε activity.

  16. Wind vs. Biofuels: Addressing Climate, Health and Energy

    SciTech Connect (OSTI)

    Professor Mark Jacobson

    2007-01-29

    The favored approach today for addressing global warming is to promote a variety of options: biofuels, wind, solar thermal, solar photovoltaic, geothermal, hydroelectric, and nuclear energy and to improve efficiency. However, by far, most emphasis has been on biofuels. It is shown here, though, that current-technology biofuels cannot address global warming and may slightly increase death and illness due to ozone-related air pollution. Future biofuels may theoretically slow global warming, but only temporarily and with the cost of increased air pollution mortality. In both cases, the land required renders biofuels an impractical solution. Recent measurements and statistical analyses of U.S. and world wind power carried out at Stanford University suggest that wind combined with other options can substantially address global warming, air pollution mortality, and energy needs simultaneously.

  17. Wind versus Biofuels for Addressing Climate, Health, and Energy

    SciTech Connect (OSTI)

    Jacobson, Mark Z.

    2007-01-29

    The favored approach today for addressing global warming is to promote a variety of options: biofuels, wind, solar thermal, solar photovoltaic, geothermal, hydroelectric, and nuclear energy and to improve efficiency. However, by far, most emphasis has been on biofuels. It is shown here, though, that current-technology biofuels cannot address global warming and may slightly increase death and illness due to ozone-related air pollution. Future biofuels may theoretically slow global warming, but only temporarily and with the cost of increased air pollution mortality. In both cases, the land required renders biofuels an impractical solution. Recent measurements and statistical analyses of U.S. and world wind power carried out at Stanford University suggest that wind combined with other options can substantially address global warming, air pollution mortality, and energy needs simultaneously.

  18. Addressing the Need for Alternative Transportation Fuels: The Joint

    Office of Scientific and Technical Information (OSTI)

    BioEnergy Institute (Journal Article) | SciTech Connect Addressing the Need for Alternative Transportation Fuels: The Joint BioEnergy Institute Citation Details In-Document Search Title: Addressing the Need for Alternative Transportation Fuels: The Joint BioEnergy Institute Today, carbon-rich fossil fuels, primarily oil, coal, and natural gas, provide 85% of the energy consumed in the U.S. As world demand increases, oil reserves may become rapidly depleted. Fossil fuel use increases CO{sub

  19. Mailing Addresses and Information Numbers for Operations, Field, and Site

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Offices | Department of Energy About Energy.gov » Mailing Addresses and Information Numbers for Operations, Field, and Site Offices Mailing Addresses and Information Numbers for Operations, Field, and Site Offices Name Telephone Number U.S. Department of Energy Ames Site Office 111 TASF, Iowa State University Ames, Iowa 50011 515-294-9557 U.S. Department of Energy Argonne Site Office 9800 S. Cass Avenue Argonne, IL 60439 630-252-2000 U.S. Department of Energy Berkeley Site Office Berkeley

  20. Mailing Addresses for National Laboratories and Technology Centers |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Mailing Addresses for National Laboratories and Technology Centers Mailing Addresses for National Laboratories and Technology Centers Name Telephone Number U.S. Department of Energy Albany Research Center 1450 Queen Ave. SW Albany, OR 97321-2198 541-967-5892 U.S. Department of Energy Ames Laboratory #311 TASF, Iowa State University Ames, Iowa 50011 515-294-2680 U.S. Department of Energy Argonne National Laboratory (East) 9700 S. Cass Avenue Argonne, IL 60439 630-252-2000

  1. Post Mortem of 120k mi Light-Duty Urea SCR and DPF System | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Post Mortem of 120k mi Light-Duty Urea SCR and DPF System Post Mortem of 120k mi Light-Duty Urea SCR and DPF System Presentation given at the 2007 Diesel Engine-Efficiency & Emissions Research Conference (DEER 2007). 13-16 August, 2007, Detroit, Michigan. Sponsored by the U.S. Department of Energy's (DOE) Office of FreedomCAR and Vehicle Technologies (OFCVT). PDF icon deer07_lambert.pdf More Documents & Publications Urea SCR and DPF System for Tier 2 Diesel Light-Duty Trucks

  2. Port Huron, MI Liquefied Natural Gas Exports to Canada (Million Cubic Feet)

    U.S. Energy Information Administration (EIA) Indexed Site

    to Canada (Million Cubic Feet) Port Huron, MI Liquefied Natural Gas Exports to Canada (Million Cubic Feet) Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2013 1 2014 1 1 1 1 2 1 1 1 1 1 2015 1 1 1 1 1 - = No Data Reported; -- = Not Applicable; NA = Not Available; W = Withheld to avoid disclosure of individual company data. Release Date: 02/29/2016 Next Release Date: 03/31/2016 Referring Pages: U.S. Liquefied Natural Gas Exports by Point of Exit Port Huron, MI Natural Gas Exports to Canad

  3. Argonne Director Eric Isaacs addresses the National Press Club

    ScienceCinema (OSTI)

    Eric Isaccs

    2010-01-08

    Argonne Director Eric Isaacs addresses the National Press Club on 9/15/2009. To build a national economy based on sustainable energy, the nation must first "reignite its innovation ecology," he said. Issacs makes the case for investing in science to secure America's future.

  4. New partnership uses advanced computer science modeling to address climate

    National Nuclear Security Administration (NNSA)

    change | National Nuclear Security Administration partnership uses advanced computer science modeling to address climate change | National Nuclear Security Administration Facebook Twitter Youtube Flickr RSS People Mission Managing the Stockpile Preventing Proliferation Powering the Nuclear Navy Emergency Response Recapitalizing Our Infrastructure Countering Nuclear Terrorism About Our Programs Our History Who We Are Our Leadership Our Locations Budget Our Operations Library Bios

  5. DOE Zero Energy Ready Home Case Study: Cobblestone Homes, Midland, MI

    Broader source: Energy.gov [DOE]

    Case study of a DOE Zero Energy Ready home in Midland, MI, that scored HERS 49 without PV or HERS 44 with 1.4 kW of PV. The custom home served as a prototype and energy efficiency demonstration...

  6. Plan for addressing issues relating to oil shale plant siting

    SciTech Connect (OSTI)

    Noridin, J. S.; Donovan, R.; Trudell, L.; Dean, J.; Blevins, A.; Harrington, L. W.; James, R.; Berdan, G.

    1987-09-01

    The Western Research Institute plan for addressing oil shale plant siting methodology calls for identifying the available resources such as oil shale, water, topography and transportation, and human resources. Restrictions on development are addressed: land ownership, land use, water rights, environment, socioeconomics, culture, health and safety, and other institutional restrictions. Descriptions of the technologies for development of oil shale resources are included. The impacts of oil shale development on the environment, socioeconomic structure, water availability, and other conditions are discussed. Finally, the Western Research Institute plan proposes to integrate these topics to develop a flow chart for oil shale plant siting. Western Research Institute has (1) identified relative topics for shale oil plant siting, (2) surveyed both published and unpublished information, and (3) identified data gaps and research needs. 910 refs., 3 figs., 30 tabs.

  7. Briefing Memo: Enhancing Resilience in Energy Infrastructure and Addressing Vulnerabilities

    Broader source: Energy.gov [DOE]

    Quadrennial Energy Review Task Force Secretariat and Energy Policy and Systems Analysis Staff, U. S. Department of Energy Public Meeting on “Enhancing Resilience in Energy Infrastructure and Addressing Vulnerabilities” On Friday, April 11, 2014, at 10 a.m. in room HVC-215 of the U.S. Capitol, the Department of Energy (DOE), acting as the Secretariat for the Quadrennial Energy Review Task Force, will hold a public meeting to discuss and receive comments on issues related to the Quadrennial Energy Review (QER). The meeting will focus on infrastructure vulnerabilities related to the electricity, natural gas and petroleum transmission, storage and distribution systems (TS&D). The meeting will consist of two facilitated panels of experts on identifying and addressing vulnerabilities within the nation’s energy TS&D infrastructure. Following the panels, an opportunity will be provided for public comment via an open microphone session.

  8. Agenda: Enhancing Energy Infrastructure Resiliency and Addressing Vulnerabilities

    Broader source: Energy.gov [DOE]

    Quadrennial Energy Review Task Force Secretariat and Energy Policy and Systems Analysis Staff, U. S. Department of Energy (DOE) Public Meeting on “Enhancing Resilience in Energy Infrastructure and Addressing Vulnerabilities” On Friday, April 11, 2014, at 10 a.m. in room HVC-215 of the U.S. Capitol, the Department of Energy (DOE), acting as the Secretariat for the Quadrennial Energy Review Task Force, will hold a public meeting to discuss and receive comments on issues related to the Quadrennial Energy Review (QER). The meeting will focus on infrastructure vulnerabilities related to the electricity, natural gas and petroleum transmission, storage and distribution systems (TS&D). The meeting will consist of two facilitated panels of experts on identifying and addressing vulnerabilities within the nation’s energy TS&D infrastructure. Following the panels, an opportunity will be provided for public comment via an open microphone session.

  9. UK Energy Minister to Address World Renewable Energy Congress - News

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Releases | NREL UK Energy Minister to Address World Renewable Energy Congress Conference, Expo to Bring International 'Clean Energy' experts to Denver April 7, 2004 Golden, Colo. - Stephen Timms, energy minister for the United Kingdom will speak to delegates from as many as 100 nations at the opening ceremony of the eighth World Renewable Energy Congress (WREC VIII) in Denver on Aug. 30. Expected to be the world's largest gathering of renewable energy experts, WREC VIII will provide a forum

  10. Secretary Bodman Addresses IAEA General Conference in Vienna | Department

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of Energy IAEA General Conference in Vienna Secretary Bodman Addresses IAEA General Conference in Vienna September 18, 2006 - 8:53am Addthis Highlights President Bush's global initiatives to expand international access to nuclear energy and promote nonproliferation VIENNA, AUSTRIA - U.S. Secretary of Energy Samuel W. Bodman today discussed the need to further expand international cooperative work in safely expanding the use of nuclear energy as a clean and affordable energy source while

  11. Secretary Bodman Addresses Turkmenistan Industrial Oil and Gas Exhibition |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Turkmenistan Industrial Oil and Gas Exhibition Secretary Bodman Addresses Turkmenistan Industrial Oil and Gas Exhibition November 16, 2007 - 4:31pm Addthis Holds Bilateral Discussion with President of Turkmenistan on Opening of Markets, Increased Investment, and Multiple Trade Routes ASHGABAT, TURKMENISTAN - U.S. Secretary of Energy Samuel W. Bodman today held bilateral energy discussions with the President of Turkmenistan and other senior Turkmenistan officials and

  12. Smart Grid RFI: Addressing Policy and Logistical Challenges, Comments from

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    the Edison Electric Institute | Department of Energy Challenges, Comments from the Edison Electric Institute Smart Grid RFI: Addressing Policy and Logistical Challenges, Comments from the Edison Electric Institute The Edison Electric Institute ("EEI"), on behalf of its member companies, hereby submits the following comments in response to the request by the Department of Energy ("DOE" or "Department") for information on a wide range of issues dealing with Smart

  13. Smart Grid RFI: Addressing Policy and Logistical Challenges. Comments of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    the Alliance to Save Energy. | Department of Energy Challenges. Comments of the Alliance to Save Energy. Smart Grid RFI: Addressing Policy and Logistical Challenges. Comments of the Alliance to Save Energy. The Alliance to Save Energy is a coalition of prominent business, government, environmental, and consumer leaders who promote the efficient use of energy worldwide to benefit consumers, the environment, economy, and national security. The Alliance to Save Energy (the Alliance) thanks the

  14. Community Leaders to Address Energy Solutions Through Leadership Program -

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    News Releases | NREL Community Leaders to Address Energy Solutions Through Leadership Program May 16, 2007 Thirteen local community leaders were chosen to join the U.S. Department of Energy's (DOE) National Renewable Energy Laboratory's (NREL) Executive Energy Leadership program. Energy Execs will participate in monthly educational sessions covering topics such as solar technology, wind energy and transportation of the future. Sessions will include an in depth look at future markets and

  15. Addressing Challenges of Identifying Geometrically Diverse Sets of

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Crystalline Porous Materials | Center for Gas SeparationsRelevant to Clean Energy Technologies | Blandine Jerome Addressing Challenges of Identifying Geometrically Diverse Sets of Crystalline Porous Materials Previous Next List R. L. Martin, B. Smit, and M. Haranczyk, J. Chem Inf. Model. 52 (2), 308 (2012) DOI: 10.1021/ci200386x Abstract Image Abstract: Crystalline porous materials have a variety of uses, such as for catalysis and separations. Identifying suitable materials for a given

  16. Smart Grid RFI: Addressing Policy and Logistical Challenges

    Energy Savers [EERE]

    Electricity Delivery and Energy Reliability 1000 Independence Avenue, SW Room 8H033 Washington, DC 20585 Submitted electronically via smartgridpolicy@hq.doe.gov Smart Grid Request for Information: Addressing Policy and Logistical Challenges Comments of the Alliance to Save Energy The Alliance to Save Energy (the Alliance) thanks the Department of Energy for the opportunity to comment on broad issues of policy and logistical challenges faced in smart grid implementation. The Alliance to Save

  17. Energy Department Addresses Largest Gathering of Geothermal Energy Stakeholders

    Broader source: Energy.gov [DOE]

    U.S. Department of Energy investments are tapping a vast resource of clean, baseload energy from the earth's heat, according to Douglas Hollett, Program Manager for the Department's Geothermal Technologies Office. Hollett addressed over 1,000 this week at the annual conference of the Geothermal Resources Council (GRC) in Reno, Nevadathe industry's largest annual gathering of geothermal energy stakeholders in the nation.

  18. Addressing Policy and Logistical Challenges to Smart Grid Implementation:

    Energy Savers [EERE]

    Comments by the Office of the Ohio Consumers' Counsel | Department of Energy Smart Grid Implementation: Comments by the Office of the Ohio Consumers' Counsel Addressing Policy and Logistical Challenges to Smart Grid Implementation: Comments by the Office of the Ohio Consumers' Counsel The Office of the Ohio Consumers' Counsel ("OCC") hereby submits the following comments in response to the United States Department of Energy ("DOE") Request for Information

  19. Addressing Policy and Logistical Challenges to smart grid Implementation:

    Energy Savers [EERE]

    eMeter Response to Department of Energy RFI | Department of Energy smart grid Implementation: eMeter Response to Department of Energy RFI Addressing Policy and Logistical Challenges to smart grid Implementation: eMeter Response to Department of Energy RFI eMeter is a smart grid software company that provides smart network application platform (SNAP) software to integrate smart meters and smart grid communications networks and devices with utility IT systems. eMeter also provides smart grid

  20. MiR-18a regulates the proliferation, migration and invasion of human glioblastoma cell by targeting neogenin

    SciTech Connect (OSTI)

    Song, Yichen; Wang, Ping; Zhao, Wei; Yao, Yilong; Liu, Xiaobai; Ma, Jun; Xue, Yixue; Liu, Yunhui

    2014-05-15

    MiR-17-92 cluster has recently been reported as an oncogene in some tumors. However, the association of miR-18a, an important member of this cluster, with glioblastoma remains unknown. Therefore, this study aims to investigate the expression of miR-18a in glioblastoma and its role in biological behavior of U87 and U251 human glioblastoma cell lines. Quantitative RT-PCR results showed that miR-18a was highly expressed in glioblastoma tissues and U87 and U251 cell lines compared with that in human brain tissues and primary normal human astrocytes, and the expression levels were increased along with the rising pathological grades of glioblastoma. Neogenin was identified as the target gene of miR-18a by dual-luciferase reporter assays. RT-PCR and western blot results showed that its expression levels were decreased along with the rising pathological grades of glioblastoma. Inhibition of miR-18a expression was established by transfecting exogenous miR-18a inhibitor into U87 and U251 cells, and its effects on the biological behavior of glioblastoma cells were studied using CCK-8 assay, transwell assay and flow cytometry. Inhibition of miR-18a expression in U87 and U251 cells significantly up-regulated neogenin, and dramatically suppressed the abilities of cell proliferation, migration and invasion, induced cell cycle arrest and promoted cellular apoptosis. Collectively, these results suggest that miR-18a may regulate biological behavior of human glioblastoma cells by targeting neogenin, and miR-18a can serve as a potential target in the treatment of glioblastoma. - Highlights: MiR-18a was highly expressed in glioblastoma tissues and U87 and U251 cell lines. Neogenin was identified as the target gene of miR-18a. Neogenin expressions were decreased along with the rising pathological grades of glioblastoma. Inhibition of miR-18a suppressed biological behavior of glioma cells by up-regulating neogenin.

  1. NEW APPROACH TO ADDRESSING GAS GENERATION IN RADIOACTIVE MATERIAL PACKAGING

    SciTech Connect (OSTI)

    Watkins, R; Leduc, D; Askew, N

    2009-06-25

    Safety Analysis Reports for Packaging (SARP) document why the transportation of radioactive material is safe in Type A(F) and Type B shipping containers. The content evaluation of certain actinide materials require that the gas generation characteristics be addressed. Most packages used to transport actinides impose extremely restrictive limits on moisture content and oxide stabilization to control or prevent flammable gas generation. These requirements prevent some users from using a shipping container even though the material to be shipped is fully compliant with the remaining content envelope including isotopic distribution. To avoid these restrictions, gas generation issues have to be addressed on a case by case basis rather than a one size fits all approach. In addition, SARP applicants and review groups may not have the knowledge and experience with actinide chemistry and other factors affecting gas generation, which facility experts in actinide material processing have obtained in the last sixty years. This paper will address a proposal to create a Gas Generation Evaluation Committee to evaluate gas generation issues associated with Safety Analysis Reports for Packaging material contents. The committee charter could include reviews of both SARP approved contents and new contents not previously evaluated in a SARP.

  2. miR-7 and miR-218 epigenetically control tumor suppressor genes RASSF1A and Claudin-6 by targeting HoxB3 in breast cancer

    SciTech Connect (OSTI)

    Li, Qiaoyan; Zhu, Fufan; Chen, Puxiang

    2012-07-20

    Highlights: Black-Right-Pointing-Pointer Both miR-7 and miR-218 down-regulates HoxB3 expression by targeting the 3 Prime -UTR of HoxB3 mRNA. Black-Right-Pointing-Pointer A reverse correlation between the levels of endogenous miR-7, miR218 and HoxB3 expression. Black-Right-Pointing-Pointer Epigenetic changes involve in the reactivation of HoxB3. Black-Right-Pointing-Pointer Both miRNAs inhibits the cell cycle and clone formation of breast cancer cells. -- Abstract: Many microRNAs have been implicated as key regulators of cellular growth and differentiation and have been found to dysregulate proliferation in human tumors, including breast cancer. Cancer-linked microRNAs also alter the epigenetic landscape by way of DNA methylation and post-translational modifications of histones. Aberrations in Hox gene expression are important for oncogene or tumor suppressor during abnormal development and malignancy. Although recent studies suggest that HoxB3 is critical in breast cancer, the putative role(s) of microRNAs impinging on HoxB3 is not yet fully understood. In this study, we found that the expression levels of miR-7 and miR-218 were strongly and reversely associated with HoxB3 expression. Stable overexpression of miR-7 and miR-218 was accompanied by reactivation of tumor suppressor genes including RASSF1A and Claudin-6 by means of epigenetic switches in DNA methylation and histone modification, giving rise to inhibition of the cell cycle and clone formation of breast cancer cells. The current study provides a novel link between overexpression of collinear Hox genes and multiple microRNAs in human breast malignancy.

  3. SNR Denton US LLP 1301 K Street, NW Suite 600, East Tower Washington, DC 20005-3364 USA

    Broader source: Energy.gov (indexed) [DOE]

    SNR Denton US LLP 1301 K Street, NW Suite 600, East Tower Washington, DC 20005-3364 USA Thomas C. Jensen Partner thomas.jensen@snrdenton.com D +1 202 408 3956 M 703 304 5211 T +1 202 408 6400 F +1 202 408 6399 snrdenton.com March 28, 2012 BY E-MAIL Lamont Jackson Office of Electricity Delivery and Energy Reliability Mail Code: OE-20 U.S. Department of Energy 1000 Independence Avenue SW Washington, DC 20585 Re: OE Docket No. RRTT-IR-001 Dear Mr. Jackson:: This letter is submitted on behalf of PPL

  4. 3610 N. 44th Street, Suite 250, Phoenix, AZ 85018 ● Phone 602-808-2004 ●

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    10 N. 44th Street, Suite 250, Phoenix, AZ 85018 ● Phone 602-808-2004 ● Fax 602-808-2099 ● www.sunzia.net October 17, 2013 Transmitted via electronic mail to juliea.smith@hq.doe.gov and christopher.lawrence@hq.doe.gov Subject: SunZia Southwest Transmission Project comments on Department of Energy's August 29, 2013 Federal Register Notice regarding Improving Performance of Federal Permitting and Review of Infrastructure Projects. The following comments are provided to the Department of

  5. Sandia seeks to address two of the most

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    seeks to address two of the most daunting problems facing humankind in the twenty-first century: energy security and climate change. The vision for achieving this is captured in one deceptively simple chemical equation that defines solar fuels production: Solar Energy + xCO2 + (x+1) H2O CxH2x+2 + (1.5x+0.5) O2. (liquid hydrocarbon fuel) Solar irradiation is a sustainable energy source of a magnitude sufficient to meet projections for global energy demand, provided it is used efficiently. The

  6. Content-addressable memory based enforcement of configurable policies

    DOE Patents [OSTI]

    Berg, Michael J

    2014-05-06

    A monitoring device for monitoring transactions on a bus includes content-addressable memory ("CAM") and a response policy unit. The CAM includes an input coupled to receive a bus transaction tag based on bus traffic on the bus. The CAM stores data tags associated with rules of a security policy to compare the bus transaction tag to the data tags. The CAM generates an output signal indicating whether one or more matches occurred. The response policy unit is coupled to the CAM to receive the output signal from the CAM and to execute a policy action in response to the output signal.

  7. A novel electron gun with an independently addressable cathode array.

    SciTech Connect (OSTI)

    Rudys, Joseph Matthew; Reed, Kim Warren; Pea, Gary Edward; Schneider, Larry X.

    2006-08-01

    The design of a novel electron gun with an array of independently addressable cathode elements is presented. Issues relating to operation in a 6.5 Tesla axial magnetic field are discussed. Simulations with the TriComp [1] electromagnetic field code that were used to determine the space charge limited tube characteristic and to model focusing of the electron beam in the magnetic field are reviewed. Foil heating and stress calculations are discussed. The results of CYLTRAN [2] simulations yielding the energy spectrum of the electron beam and the current transmitted through the foil window are presented.

  8. Imulation of polymer forming processes - addressing industrial needs

    SciTech Connect (OSTI)

    Thibault, F.; DiRaddo, R. [Industrial Materials Institute-National Research Council (Canada)

    2011-05-04

    The objective of this paper is to present the development of simulation and design optimization capabilities, for polymer forming processes, in the context of addressing industrial needs. Accomplishments generated from close to twenty years of research in this field, at the National Research Council (NRC), are presented. Polymer forming processes such as extrusion blow moulding, stretch blow moulding and thermoforming have been the focus of the work, yet the research is extendable to similar polymer forming operations such as micro-blow moulding, sheet blow moulding and composites stamping. The research considers material models, process sequence integration and design optimization, derivative processes and 3D finite elements with multi-body contact.

  9. Recent NRC research activities addressing valve and pump issues

    SciTech Connect (OSTI)

    Morrison, D.L.

    1996-12-01

    The mission of the U.S. Nuclear Regulatory Commission (NRC) is to ensure the safe design, construction, and operation of commercial nuclear power plants and other facilities in the U.S.A. One of the main roles that the Office of Nuclear Regulatory Research (RES) plays in achieving the NRC mission is to plan, recommend, and implement research programs that address safety and technical issues deemed important by the NRC. The results of the research activities provide the bases for developing NRC positions or decisions on these issues. Also, RES performs confirmatory research for developing the basis to evaluate industry responses and positions on various regulatory requirements. This presentation summarizes some recent RES supported research activities that have addressed safety and technical issues related to valves and pumps. These activities include the efforts on determining valve and motor-operator responses under dynamic loads and pressure locking events, evaluation of monitoring equipment, and methods for detecting and trending aging of check valves and pumps. The role that RES is expected to play in future years to fulfill the NRC mission is also discussed.

  10. Compensated individually addressable array technology for human breast imaging

    DOE Patents [OSTI]

    Lewis, D. Kent (San Francisco, CA)

    2003-01-01

    A method of forming broad bandwidth acoustic or microwave beams which encompass array design, array excitation, source signal preprocessing, and received signal postprocessing. This technique uses several different methods to achieve improvement over conventional array systems. These methods are: 1) individually addressable array elements; 2) digital-to-analog converters for the source signals; 3) inverse filtering from source precompensation; and 4) spectral extrapolation to expand the bandwidth of the received signals. The components of the system will be used as follows: 1) The individually addressable array allows scanning around and over an object, such as a human breast, without any moving parts. The elements of the array are broad bandwidth elements and efficient radiators, as well as detectors. 2) Digital-to-analog converters as the source signal generators allow virtually any radiated field to be created in the half-space in front of the array. 3) Preprocessing allows for corrections in the system, most notably in the response of the individual elements and in the ability to increase contrast and resolution of signal propagating through the medium under investigation. 4) Postprocessing allows the received broad bandwidth signals to be expanded in a process similar to analytic continuation. Used together, the system allows for compensation to create beams of any desired shape, control the wave fields generated to correct for medium differences, and improve contract and resolution in and through the medium.

  11. Health assessment for Hooker Chemical (102nd Street Landfill), Niagara Falls, New York, Region 2. CERCLIS No. NYD980506810. Preliminary report

    SciTech Connect (OSTI)

    Not Available

    1989-06-01

    The 102nd Street Landfill is two sites that comprise 22 acres. Occidental Chemical Corporation (OCC) and its predecessor, the Oldbury Electrochemical Company, deposited approximately 23,500 tons of mixed organic solvents, organic and inorganic phosphates, and related chemicals. Included in the site are approximately 300 tons of hexachlorocyclohexane process cake, including lindane. In addition, brine sludge, fly ash, electrochemical cell parts and related equipment in unknown quantities were dumped at the site. On-site contamination of the 102nd Street Landfill includes soils contaminated with non-aqueous phase liquids on both portions of the Landfill. Off-site contamination, based on current studies, results from contaminated ground-water leaching into the Niagara River which causes contamination of the river water, sediments, and aquatic organisms, including fish. The 102nd Street Landfill continues to represent a potential public health threat.

  12. Material Activation Benchmark Experiments at the NuMI Hadron Absorber Hall in Fermilab

    SciTech Connect (OSTI)

    Matsumura, H.; Matsuda, N.; Kasugai, Y.; Toyoda, A.; Yashima, H.; Sekimoto, S.; Iwase, H.; Oishi, K.; Sakamoto, Y.; Nakashima, H.; Leveling, A.; Boehnlein, D.; Lauten, G.; Mokhov, N.; Vaziri, K.

    2014-06-15

    In our previous study, double and mirror symmetric activation peaks found for Al and Au arranged spatially on the back of the Hadron absorber of the NuMI beamline in Fermilab were considerably higher than those expected purely from muon-induced reactions. From material activation bench-mark experiments, we conclude that this activation is due to hadrons with energy greater than 3 GeV that had passed downstream through small gaps in the hadron absorber.

  13. Western Wind Strategy: Addressing Critical Issues for Wind Deployment

    SciTech Connect (OSTI)

    Douglas Larson; Thomas Carr

    2012-03-30

    The goal of the Western Wind Strategy project was to help remove critical barriers to wind development in the Western Interconnection. The four stated objectives of this project were to: (1) identify the barriers, particularly barriers to the operational integration of renewables and barriers identified by load-serving entities (LSEs) that will be buying wind generation, (2) communicate the barriers to state officials, (3) create a collaborative process to address those barriers with the Western states, utilities and the renewable industry, and (4) provide a role model for other regions. The project has been on the forefront of identifying and informing state policy makers and utility regulators of critical issues related to wind energy and the integration of variable generation. The project has been a critical component in the efforts of states to push forward important reforms and innovations that will enable states to meet their renewable energy goals and lower the cost to consumers of integrating variable generation.

  14. Targeting miR-21 enhances the sensitivity of human colon cancer HT-29 cells to chemoradiotherapy in vitro

    SciTech Connect (OSTI)

    Deng, Jun; Lei, Wan; Fu, Jian-Chun; Zhang, Ling; Li, Jun-He; Xiong, Jian-Ping

    2014-01-17

    Highlight: MiR-21 plays a significant role in 5-FU resistance. This role might be attributed to targeting of hMSH2 as well as TP and DPD via miR-21 targeted hMSH2. Indirectly targeted TP and DPD to influence 5-FU chemotherapy sensitivity. -- Abstract: 5-Fluorouracil (5-FU) is a classic chemotherapeutic drug that has been widely used for colorectal cancer treatment, but colorectal cancer cells are often resistant to primary or acquired 5-FU therapy. Several studies have shown that miR-21 is significantly elevated in colorectal cancer. This suggests that this miRNA might play a role in this resistance. In this study, we investigated this possibility and the possible mechanism underlying this role. We showed that forced expression of miR-21 significantly inhibited apoptosis, enhanced cell proliferation, invasion, and colony formation ability, promoted G1/S cell cycle transition and increased the resistance of tumor cells to 5-FU and X radiation in HT-29 colon cancer cells. Furthermore, knockdown of miR-21 reversed these effects on HT-29 cells and increased the sensitivity of HT-29/5-FU to 5-FU chemotherapy. Finally, we showed that miR-21 targeted the human mutS homolog2 (hMSH2), and indirectly regulated the expression of thymidine phosphorylase (TP) and dihydropyrimidine dehydrogenase (DPD). These results demonstrate that miR-21 may play an important role in the 5-FU resistance of colon cancer cells.

  15. miR-21 modulates tumor outgrowth induced by human adipose tissue-derived mesenchymal stem cells in vivo

    SciTech Connect (OSTI)

    Shin, Keun Koo; Lee, Ae Lim; Kim, Jee Young; Medical Research Center for Ischemic Tissue Engineering, Pusan National University, Yangsan, Gyeongnam 626-870; BK21 Medical Science Education Center, School of Medicine, Pusan National University, Yangsan, Gyeongnam 626-870 ; Lee, Sun Young; Medical Research Center for Ischemic Tissue Engineering, Pusan National University, Yangsan, Gyeongnam 626-870 ; Bae, Yong Chan; Jung, Jin Sup

    2012-06-15

    Highlights: Black-Right-Pointing-Pointer miR-21 modulates hADSC-induced increase of tumor growth. Black-Right-Pointing-Pointer The action is mostly mediated by the modulation of TGF-{beta} signaling. Black-Right-Pointing-Pointer Inhibition of miR-21 enhances the blood flow recovery in hindlimb ischemia. -- Abstract: Mesenchymal stem cells (MSCs) have generated a great deal of interest in clinical situations, due principally to their potential use in regenerative medicine and tissue engineering applications. However, the therapeutic application of MSCs remains limited, unless the favorable effects of MSCs on tumor growth in vivo, and the long-term safety of the clinical applications of MSCs, can be more thoroughly understood. In this study, we determined whether microRNAs can modulate MSC-induced tumor outgrowth in BALB/c nude mice. Overexpression of miR-21 in human adipose-derived stem cells (hADSCs) inhibited hADSC-induced tumor growth, and inhibition of miR-21 increased it. Downregulation of transforming growth factor beta receptor II (TGFBR2), but not of signal transducer and activator of transcription 3, in hADSCs showed effects similar to those of miR-21 overexpression. Downregulation of TGFBR2 and overexpression of miR21 decreased tumor vascularity. Inhibition of miR-21 and the addition of TGF-{beta} increased the levels of vascular endothelial growth factor and interleukin-6 in hADSCs. Transplantation of miR-21 inhibitor-transfected hADSCs increased blood flow recovery in a hind limb ischemia model of nude mice, compared with transplantation of control oligo-transfected cells. These findings indicate that MSCs might favor tumor growth in vivo. Thus, it is necessary to study the long-term safety of this technique before MSCs can be used as therapeutic tools in regenerative medicine and tissue engineering.

  16. Addressing the Need for Independence in the CSE Model

    SciTech Connect (OSTI)

    Abercrombie, Robert K; Ferragut, Erik M; Sheldon, Frederick T; Grimaila, Michael R

    2011-01-01

    Abstract Information system security risk, defined as the product of the monetary losses associated with security incidents and the probability that they occur, is a suitable decision criterion when considering different information system architectures. Risk assessment is the widely accepted process used to understand, quantify, and document the effects of undesirable events on organizational objectives so that risk management, continuity of operations planning, and contingency planning can be performed. One technique, the Cyberspace Security Econometrics System (CSES), is a methodology for estimating security costs to stakeholders as a function of possible risk postures. In earlier works, we presented a computational infrastructure that allows an analyst to estimate the security of a system in terms of the loss that each stakeholder stands to sustain, as a result of security breakdowns. Additional work has applied CSES to specific business cases. The current state-of-the-art of CSES addresses independent events. In typical usage, analysts create matrices that capture their expert opinion, and then use those matrices to quantify costs to stakeholders. This expansion generalizes CSES to the common real-world case where events may be dependent.

  17. Software programs that address site-specific inventory characteristics issues.

    SciTech Connect (OSTI)

    Dare, J. H.; Cournoyer, M. E.

    2001-01-01

    The proper characterization of Hazardous, Mixed Low-Level, and Mixed Transuranic waste enhances productivity and safety. Hazardous material criteria that need to be considered include physical and health hazards inherent to the waste stream. Other factors that may influence characterization include: particulate diameter, complexing or chelating agent properties, lead, and mercury content, pressurized containers, and P-listed wastes. To meet these requirements are only a simple matter of generating a database with the proper fields. Manufactures and institutional databases bank huge sources of information, such as, work control documents, substance identification, container types, components of mixtures, physical property data, and regulatory data. In this report, utilization of commercially available software programs to take advantage of these resources in addressing waste characterization issues are presented. The application of user-friendly programs eliminates part of the tediousness associated with the complex requirements of certifying to general waste acceptance criteria with minimal impact on programmatic work. In other words, tapping into manufacturer and institutional database provides a way to take advantage of the combined expertise of these resources in managing a cost effective waste certification program as well as adding a quality assurance element to the program.

  18. Hidden benefits of electric vehicles for addressing climate change

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Li, Canbing; Cao, Yijia; Zhang, Mi; Wang, Jianhui; Liu, Jianguo; Shi, Haiqing; Geng, Yinghui

    2015-03-19

    There is an increasingly hot debate on whether the replacement of conventional vehicles (CVs) by electric vehicles (EVs) should be delayed or accelerated since EVs require higher cost and cause more pollution than CVs in the manufacturing process. Here we reveal two hidden benefits of EVs for addressing climate change to support the imperative acceleration of replacing CVs with EVs. As EVs emit much less heat than CVs within the same mileage, the replacement can mitigate urban heat island effect (UHIE) to reduce the energy consumption of air conditioners, benefitting local and global climates. To demonstrate these effects brought bymore » the replacement of CVs by EVs, we take Beijing, China, as an example. EVs emit only 19.8% of the total heat emitted by CVs per mile. The replacement of CVs by EVs in 2012 could have mitigated the summer heat island intensity (HII) by about 0.94°C, reduced the amount of electricity consumed daily by air conditioners in buildings by 14.44 million kilowatt-hours (kWh), and reduced daily CO₂ emissions by 10,686 tonnes.« less

  19. Addressing Energy Demand through Demand Response. International Experiences and Practices

    SciTech Connect (OSTI)

    Shen, Bo; Ghatikar, Girish; Ni, Chun Chun; Dudley, Junqiao; Martin, Phil; Wikler, Greg

    2012-06-01

    Demand response (DR) is a load management tool which provides a cost-effective alternative to traditional supply-side solutions to address the growing demand during times of peak electrical load. According to the US Department of Energy (DOE), demand response reflects “changes in electric usage by end-use customers from their normal consumption patterns in response to changes in the price of electricity over time, or to incentive payments designed to induce lower electricity use at times of high wholesale market prices or when system reliability is jeopardized.” 1 The California Energy Commission (CEC) defines DR as “a reduction in customers’ electricity consumption over a given time interval relative to what would otherwise occur in response to a price signal, other financial incentives, or a reliability signal.” 2 This latter definition is perhaps most reflective of how DR is understood and implemented today in countries such as the US, Canada, and Australia where DR is primarily a dispatchable resource responding to signals from utilities, grid operators, and/or load aggregators (or DR providers).

  20. Hidden benefits of electric vehicles for addressing climate change

    SciTech Connect (OSTI)

    Li, Canbing; Cao, Yijia; Zhang, Mi; Wang, Jianhui; Liu, Jianguo; Shi, Haiqing; Geng, Yinghui

    2015-03-19

    There is an increasingly hot debate on whether the replacement of conventional vehicles (CVs) by electric vehicles (EVs) should be delayed or accelerated since EVs require higher cost and cause more pollution than CVs in the manufacturing process. Here we reveal two hidden benefits of EVs for addressing climate change to support the imperative acceleration of replacing CVs with EVs. As EVs emit much less heat than CVs within the same mileage, the replacement can mitigate urban heat island effect (UHIE) to reduce the energy consumption of air conditioners, benefitting local and global climates. To demonstrate these effects brought by the replacement of CVs by EVs, we take Beijing, China, as an example. EVs emit only 19.8% of the total heat emitted by CVs per mile. The replacement of CVs by EVs in 2012 could have mitigated the summer heat island intensity (HII) by about 0.94C, reduced the amount of electricity consumed daily by air conditioners in buildings by 14.44 million kilowatt-hours (kWh), and reduced daily CO? emissions by 10,686 tonnes.

  1. MiR-145 is downregulated in human ovarian cancer and modulates cell growth and invasion by targeting p70S6K1 and MUC1

    SciTech Connect (OSTI)

    Wu, Huijuan; Xiao, ZhengHua; Wang, Ke; Liu, Wenxin; Hao, Quan

    2013-11-29

    Highlights: MiR-145 is downregulated in human ovarian cancer. MiR-145 targets p70S6K1 and MUC1. p70S6K1 and MUC1 are involved in miR-145 mediated tumor cell growth and cell invasion, respectively. -- Abstract: MicroRNAs (miRNAs) are a family of small non-coding RNA molecules that regulate gene expression at post-transcriptional levels. Previous studies have shown that miR-145 is downregulated in human ovarian cancer; however, the roles of miR-145 in ovarian cancer growth and invasion have not been fully demonstrated. In the present study, Northern blot and qRT-PCR analysis indicate that miR-145 is downregulated in ovarian cancer tissues and cell lines, as well as in serum samples of ovarian cancer, compared to healthy ovarian tissues, cell lines and serum samples. Functional studies suggest that miR-145 overexpression leads to the inhibition of colony formation, cell proliferation, cell growth viability and invasion, and the induction of cell apoptosis. In accordance with the effect of miR-145 on cell growth, miR-145 suppresses tumor growth in vivo. MiR-145 is found to negatively regulate P70S6K1 and MUC1 protein levels by directly targeting their 3?UTRs. Importantly, the overexpression of p70S6K1 and MUC1 can restore the cell colony formation and invasion abilities that are reduced by miR-145, respectively. MiR-145 expression is increased after 5-aza-CdR treatment, and 5-aza-CdR treatment results in the same phenotype as the effect of miR-145 overexpression. Our study suggests that miR-145 modulates ovarian cancer growth and invasion by suppressing p70S6K1 and MUC1, functioning as a tumor suppressor. Moreover, our data imply that miR-145 has potential as a miRNA-based therapeutic target for ovarian cancer.

  2. Regulatory approaches for addressing dissolved oxygen concerns at hydropower facilities

    SciTech Connect (OSTI)

    Peterson, Mark J.; Cada, Glenn F.; Sale, Michael J.; Eddlemon, Gerald K.

    2003-03-01

    Low dissolved oxygen (DO) concentrations are a common water quality problem downstream of hydropower facilities. At some facilities, structural improvements (e.g. installation of weir dams or aerating turbines) or operational changes (e.g., spilling water over the dam) can be made to improve DO levels. In other cases, structural and operational approaches are too costly for the project to implement or are likely to be of limited effectiveness. Despite improvements in overall water quality below dams in recent years, many hydropower projects are unable to meet state water quality standards for DO. Regulatory agencies in the U.S. are considering or implementing dramatic changes in their approach to protecting the quality of the Nations waters. New policies and initiatives have emphasized flexibility, increased collaboration and shared responsibility among all parties, and market-based, economic incentives. The use of new regulatory approaches may now be a viable option for addressing the DO problem at some hydropower facilities. This report summarizes some of the regulatory-related options available to hydropower projects, including negotiation of site-specific water quality criteria, use of biological monitoring, watershed-based strategies for the management of water quality, and watershed-based trading. Key decision points center on the health of the local biological communities and whether there are contributing impacts (i.e., other sources of low DO effluents) in the watershed. If the biological communities downstream of the hydropower project are healthy, negotiation for site-specific water quality standards or biocriteria (discharge performance criteria based on characteristics of the aquatic biota) might be pursued. If there are other effluent dischargers in the watershed that contribute to low DO problems, watershed-scale strategies and effluent trading may be effective. This report examines the value of regulatory approaches by reviewing their use in other

  3. Addressing Water Consumption of Evaporative Coolers with Greywater

    SciTech Connect (OSTI)

    Sahai, Rashmi; Shah, Nihar; Phadke, Amol

    2012-07-01

    Evaporative coolers (ECs) provide significant gains in energy efficiency compared to vapor compression air conditioners, but simultaneously have significant onsite water demand. This can be a major barrier to deployment in areas of the world with hot and arid climates. To address this concern, this study determined where in the world evaporative cooling is suitable, the water consumption of ECs in these cities, and the potential that greywater can be used reduce the consumption of potable water in ECs. ECs covered 69percent of the cities where room air conditioners are may be deployed, based on comfort conditions alone. The average water consumption due to ECs was found to be 400 L/household/day in the United States and Australia, with the potential for greywater to provide 50percent this amount. In the rest of the world, the average water consumption was 250 L/household/day, with the potential for greywater to supply 80percent of this amount. Home size was the main factor that contributed to this difference. In the Mediterranean, the Middle East, Northern India, and the Midwestern and Southwestern United States alkalinity levels are high and water used for bleeding will likely contribute significantly to EC water consumption. Although technically feasible, upfront costs for household GW systems are currently high. In both developed and developing parts of the world, however, a direct EC and GW system is cost competitive with conventional vapor compression air conditioners. Moreover, in regions of the world that face problems of water scarcity the benefits can substantially outweigh the costs.

  4. Testing CPT conservation using the NuMI neutrino beam with the MINOS experiment

    SciTech Connect (OSTI)

    Auty, David John

    2010-05-01

    The MINOS experiment was designed to measure neutrino oscillation parameters with muon neutrinos. It achieves this by measuring the neutrino energy spectrum and flavor composition of the man-made NuMI neutrino beam 1km after the beam is formed and again after 735 km. By comparing the two spectra it is possible to measure the oscillation parameters. The NuMI beam is made up of 7.0% {bar {nu}}{sub {mu}}, which can be separated from the {nu}{sub {mu}} because the MINOS detectors are magnetized. This makes it possible to study {bar {nu}}{sub {mu}} oscillations separately from those of muon neutrinos, and thereby test CPT invariance in the neutrino sector by determining the {bar {nu}}{sub {mu}} oscillation parameters and comparing them with those for {nu}{sub {mu}}, although any unknown physics of the antineutrino would appear as a difference in oscillation parameters. Such a test has not been performed with beam {bar {nu}}{sub {mu}} before. It is also possible to produce an almost pure {bar {nu}}{sub {mu}} beam by reversing the current through the magnetic focusing horns of the NuMI beamline, thereby focusing negatively, instead of positively charged particles. This thesis describes the analysis of the 7% {bar {nu}}{sub {mu}} component of the forward horn current NuMI beam. The {bar {nu}}{sub {mu}} of a data sample of 3.2 x 10{sup 20} protons on target analysis found 42 events, compared to a CPT conserving prediction of 58.3{sub -7.6}{sup +7.6}(stat.){sub -3.6}{sup +3.6}(syst.) events. This corresponds to a 1.9 {sigma} deficit, and a best fit value of {Delta}{bar m}{sub 32}{sup 2} = 18 x 10{sup -3} eV{sup 2} and sin{sup 2} 2{bar {theta}}{sub 23} = 0.55. This thesis focuses particularly on the selection of {bar {nu}}{sub {mu}} events, and investigates possible improvements of the selection algorithm. From this a different selector was chosen, which corroborated the findings of the original selector. The thesis also investigates how the systematic errors affect the precision of {Delta}{bar m}{sub 32}{sup 2} and sin{sup 2} 2{bar {theta}}{sub 23}. Furthermore, it describes a study to determine the gains of the PMTs via the single-photoelectron spectrum. The results were used as a crosscheck of the gains determined at higher intensities by an LED-based light-injection system.

  5. DOE Zero Ready Home Case Study: Cobblestone Homes, 2014 Model Home, Midland, MI

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Cobblestone Homes 2014 Model Home Midland, MI DOE ZERO ENERGY READY HOME(tm) The U.S. Department of Energy invites home builders across the country to meet the extraordinary levels of excellence and quality specified in DOE's Zero Energy Ready Home program (formerly known as Challenge Home). Every DOE Zero Energy Ready Home starts with ENERGY STAR Certified Homes Version 3.0 for an energy-efficient home built on a solid foundation of building science research. Advanced technologies are designed

  6. AMENDMENT OF SOLICITATION/MODIFICATlON OF CONTRACT MI54 I See Block 16C I

    National Nuclear Security Administration (NNSA)

    MI54 I See Block 16C I REQ. NO. Babcock & Wilcox Technical Services Pantex, LLC PO Box 30020 Amarillo, TX 79120 2. AMENDMENTIMODIFICATION NO. 1 3. EFFECTIVE DATE 1 4. REQUlSlTlONlPURCHASE 1 5. PROJECT NO. (If a ~ ~ l i c a b l e ) l.CoNTRACTIDCODE ~ . . U.S. Department of Energy National Nuclear Security Administration Service Center Property and M&O Contract Support Department P.O. Box 5400 Albuquerque, NM 87185-5400 I I 9B. DATED (SEE ITEM 1 1 ) PAGE 1 OF 2 PAGES 6. ISSUED BY CODE 1 7.

  7. Assessment of radiological releases from the NuMI facility during MINOS and NOvA operations

    SciTech Connect (OSTI)

    Martens, Mike; /Fermilab

    2007-04-01

    This report makes projections of the radiological releases from the NuMI facility during operations for the MINOS and NO ?A experiments. It includes an estimate of the radionuclide levels released into the atmosphere and the estimated tritium and sodium-22 concentrations in the NuMI sump water and Fermilab pond system. The analysis was performed for NuMI operations with a beam power on target increased from the present 400 kW design up to a possible 1500 kW with future upgrades. The total number of protons on target was assumed to be 18 x 10{sup 20} after the completion of MINOS and 78 x 10{sup 20} after the completion of NO ?A.

  8. Examples of cooler reflective streets for urban heat-island mitigation : Portland cement concrete and chip seals

    SciTech Connect (OSTI)

    Pomerantz, M.; Akbari, H.; Chang, S.-C.; Levinson, R.; Pon, B.

    2003-04-30

    Part of the urban heat island effect can be attributed to dark pavements that are commonly used on streets and parking lots. In this paper we consider two light colored, hence cooler, alternative paving materials that are in actual use in cities today. These are Portland cement concrete (PCC) pavements and chip seals. We report measurements of the albedos of some PCC and chip sealed pavements in the San Francisco Bay Area. The albedos of the PCC pavements ranged from about 0.18 to 0.35. The temperatures of some PCC pavements are also measured and calculated. We then consider how the albedos of the constituent materials of the PCC (stone, sand and cement) contribute to the albedos of the resulting finished concrete. The albedos of a set of chip sealed pavements in San Jose, CA, were measured and correlated with the times of their placement. It is found that the albedos decrease with age (and use) but remain higher than that of standard asphalt concrete (AC) for about five years. After t hat, the albedos of the chip seals are about 0.12, similar to aged AC. The fact that many PCC pavements have albedos at least twice as high as aged AC suggests that it is possible to have pavement albedos that remain high for many years.

  9. U-115: Novell GroupWise Client Address Book Processing Buffer Overflow Vulnerability

    Broader source: Energy.gov [DOE]

    The vulnerability is caused due to an error when processing Novell Address Book (".nab") files and can be exploited to cause a heap-based buffer overflow via an overly long email address.

  10. GridWise Alliance: Smart Grid RFI: Addressing Policy and Logistical...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    GridWise Alliance: Smart Grid RFI: Addressing Policy and Logistical Challenges GridWise Alliance: Smart Grid RFI: Addressing Policy and Logistical Challenges The GridWise Alliance ...

  11. How ATP3 is Addressing the Challenges of Scale-up in Algae Technology...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    How ATP3 is Addressing the Challenges of Scale-up in Algae Technology R&D How ATP3 is Addressing the Challenges of Scale-up in Algae Technology R&D Breakout Session 2-A: The Future...

  12. miR-206 is down-regulated in breast cancer and inhibits cell proliferation through the up-regulation of cyclinD2

    SciTech Connect (OSTI)

    Zhou, Jing; Tian, Ye; Li, Juan; Lu, Binbin; Sun, Ming; Zou, Yanfen; Kong, Rong; Luo, Yanhong; Shi, Yongguo; Wang, Keming; Ji, Guozhong

    2013-04-05

    Highlights: ? miR-206 was downexpressed in tumor samples compared with matched normal samples. ? Enhanced expression of miR-206 could inhibit breast cancer growth in vitro. ? Luciferase confirmed miR-206 functions as an anti-oncogene by targeting cyclinD2. ? A reverse correlation between miR-206 and cyclinD2 in breast cancer was found. -- Abstract: MicroRNAs act as important gene regulators in human genomes, and their aberrant expression is linked to many malignancies. Aberrant expression of miR-206 has been frequently reported in cancer studies; however, the role and mechanism of its function in breast cancer remains unclear. Quantitative real-time PCR was performed to detect the relative expression levels of miR-206 in breast cancer and normal breast tissues. Lower expression of miR-206 in breast cancer tissues was associated with larger tumour size and a more advanced clinical stage. Further in vitro observations showed that the enforced expression of miR-206 in MCF-7 breast cancer cells inhibited cell growth by blocking the G1/S transition and suppressed cell proliferation and colony formation, implying that miR-206 functions as a tumour suppressor in the progression of breast cancer. Interestingly, Luciferase assays first revealed that miR-206 inhibited cyclinD2 expression by targeting two binding sites in the 3?-untranslated region of cyclinD2 mRNA. qRT-PCR and Western blot assays verified that miR-206 reduced cyclinD2 expression at both the mRNA and protein levels. A reverse correlation between miR-206 and cyclinD2 expression was noted in breast cancer tissues. Altogether, our results identify a crucial tumour suppressive role of miR-206 in the progression of breast cancer, at least partly via up-regulation of the expression of cyclinD2, and suggest that miR-206 might be a candidate prognostic predictor or an anticancer therapeutic target for breast cancer patients.

  13. Validation of the MCNPX-PoliMi Code to Design a Fast-Neutron Multiplicity Counter

    SciTech Connect (OSTI)

    J. L. Dolan; A. C. Kaplan; M. Flaska; S. A. Pozzi; D. L. Chichester

    2012-07-01

    Many safeguards measurement systems used at nuclear facilities, both domestically and internationally, rely on He-3 detectors and well established mathematical equations to interpret coincidence and multiplicity-type measurements for verifying quantities of special nuclear material. Due to resource shortages alternatives to these existing He-3 based systems are being sought. Work is also underway to broaden the capabilities of these types of measurement systems in order to improve current multiplicity analysis techniques. As a part of a Material Protection, Accounting, and Control Technology (MPACT) project within the U.S. Department of Energy's Fuel Cycle Technology Program we are designing a fast-neutron multiplicity counter with organic liquid scintillators to quantify important quantities such as plutonium mass. We are also examining the potential benefits of using fast-neutron detectors for multiplicity analysis of advanced fuels in comparison with He-3 detectors and testing the performance of such designs. The designs are being developed and optimized using the MCNPX-PoliMi transport code to study detector response. In the full paper, we will discuss validation measurements used to justify the use of the MCNPX-PoliMi code paired with the MPPost multiplicity routine to design a fast neutron multiplicity counter with liquid scintillators. This multiplicity counter will be designed with the end goal of safeguarding advanced nuclear fuels. With improved timing qualities associated with liquid scintillation detectors, we can design a system that is less limited by nuclear materials of high activities. Initial testing of the designed system with nuclear fuels will take place at Idaho National Laboratory in a later stage of this collaboration.

  14. T-1025 IU SciBath-768 detector tests in MI-12

    SciTech Connect (OSTI)

    Tayloe, Rex; Cooper, R.; Garrison, L.; Thornton, T.; Rebenitsch, L.; DeJongh, Fritz; Loer, Benjamin; Ramberg, Erik; Yoo, Jonghee; /Fermilab

    2012-02-11

    This is a memorandum of understanding between the Fermi National Accelerator Laboratory (Fermilab) and the experimenters of Department of Physics and Center for Exploration of Energy and Matter, Indiana University, who have committed to participate in detector tests to be carried out during the 2012 Fermilab Neutrino program. The memorandum is intended solely for the purpose of recording expectations for budget estimates and work allocations for Fermilab, the funding agencies and the participating institutions. it reflects an arrangement that currently is satisfactory to the parties; however, it is recognized and anticipated that changing circumstances of the evolving research program will necessitate revisions. The parties agree to modify this memorandum to reflect such required adjustments. Actual contractual obligations will be set forth in separate documents. The experimenters propsoe to test their prototype 'SciBat-768' detector in the MI-12 building for 3 months (February-April) in Spring 2012. The major goal of this effort is to measure or limit the flux of beam-induced neutrons in a far-off-axis (> 45{sup o}) location of the Booster Neutrino Beamline (BNB). This flux is of interest for a proposed coherent neutral-current neutrino-argon elastic scattering experiment. A second goal is to collect more test data for the SciBath-768 to enable better understanding and calibration of the device. The SciBath-768 detector successfully ran for 3 months in the MINOS Underground Area in Fall 2011 as testbeam experiment T-1014 and is currently running above ground in the MINOS service building. For the run proposed here, the experiments are requesting: space in MI-12 in which to run the SciBath detector during February-April 2012 while the BNB is operating; technical support to help with moving the equipment on site; access to power, internet, and accelerator signals; and a small office space from which to run and monitor the experiment.

  15. 5-address

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

  16. Keynote Address

    Office of Environmental Management (EM)

    ... deactivation and decommissioning of facilities and ... Authority for use in power reactors to generate electricity ... * Current Status - The Department has not ...

  17. Pecan Street Project

    Broader source: Energy.gov [DOE]

    Slides presented in the "What’s Working in Residential Energy Efficiency Upgrade Programs Conference - Promising Approaches and Lessons Learned" on May 20, 2011 in Washington, D.C.

  18. 1414 Prince Street

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    4, 2015 Alice Lippert Senior Technical Advisor Office of Electricity Delivery and Energy Reliability U.S. ... to Request for Information: National Power Transformer Reserve Dear Ms. ...

  19. Response to Request for Information titled "Addressing Policy and

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Logistical Challenges to Smart Grid Implementation" | Department of Energy to Request for Information titled "Addressing Policy and Logistical Challenges to Smart Grid Implementation" Response to Request for Information titled "Addressing Policy and Logistical Challenges to Smart Grid Implementation" Response to Request for Information titled "Addressing Policy and Logistical Challenges to Smart Grid Implementation." urrent smart grid initiatives are

  20. NBP RFI-Addressing Policy and Logistical Challenges to Smart Grid

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Implementation. September 10, 2009 | Department of Energy NBP RFI-Addressing Policy and Logistical Challenges to Smart Grid Implementation. September 10, 2009 NBP RFI-Addressing Policy and Logistical Challenges to Smart Grid Implementation. September 10, 2009 The Telecommunications Industry Association (TIA) is pleased to provide comments on how to address the numerous challenges facing the development and deployment of smart grid technologies. Smart grid is a more robust application of

  1. U.S. Energy Secretary Addresses International Atomic Energy Agency General

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Conference | Department of Energy Addresses International Atomic Energy Agency General Conference U.S. Energy Secretary Addresses International Atomic Energy Agency General Conference September 19, 2011 - 4:48pm Addthis VIENNA, AUSTRIA - U.S. Energy Secretary Steven Chu addressed the International Atomic Energy Agency's General Conference today in Vienna. Opening with a message from President Barack Obama, Secretary Chu highlighted the importance of safety and security in the nuclear

  2. U.S. Energy Secretary Addresses International Atomic Energy Agency General

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Conference | Department of Energy Energy Secretary Addresses International Atomic Energy Agency General Conference U.S. Energy Secretary Addresses International Atomic Energy Agency General Conference September 19, 2011 - 2:24pm Addthis VIENNA, AUSTRIA - U.S. Energy Secretary Steven Chu addressed the International Atomic Energy Agency's General Conference today in Vienna. Opening with a message from President Barack Obama, Secretary Chu highlighted the importance of safety and security in

  3. Assistant Secretary Patricia Hoffman to Deliver Keynote Address at IEEE PES

    Energy Savers [EERE]

    Conference on Innovative Smart Grid Technologies | Department of Energy Patricia Hoffman to Deliver Keynote Address at IEEE PES Conference on Innovative Smart Grid Technologies Assistant Secretary Patricia Hoffman to Deliver Keynote Address at IEEE PES Conference on Innovative Smart Grid Technologies January 25, 2013 - 3:10pm Addthis Assistant Secretary Patricia Hoffman will give the keynote address at the 4th annual IEEE PES Conference on Innovative Smart Grid Technologies (ISGT 2013) on

  4. GREET Model Expanded to Better Address Biofuel Life-Cycle Analysis Research

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Questions | Department of Energy GREET Model Expanded to Better Address Biofuel Life-Cycle Analysis Research Questions GREET Model Expanded to Better Address Biofuel Life-Cycle Analysis Research Questions November 23, 2015 - 2:57pm Addthis GREET Model Expanded to Better Address Biofuel Life-Cycle Analysis Research Questions The Greenhouse gases, Regulated Emissions, and Energy use in Transportation (GREET) model allows researchers and analysts to fully evaluate the energy and emission

  5. DRSG Comments to DOE Smart Grid RFI: Addressing Policy and Logistical Challenges

    Office of Environmental Management (EM)

    DRSG Comments to DOE Smart Grid RFI: Addressing Policy and Logistical Challenges DRSG- 1 DOE Smart Grid RFI Titled "Addressing Policy and Logistical Challenges to Smart Grid Implementation" Submitted by the Demand Response and Smart Grid Coalition (DRSG) November 1, 2010 DRSG Comments to DOE Smart Grid RFI: Addressing Policy and Logistical Challenges DRSG- 2 I. Definition and Scope 1. What significant policy challenges are likely to remain unaddressed if we employ Title XIII's

  6. Genes and Genomics for Improving Energy Crops (Keynote Address - 2010 JGI User Meeting)

    ScienceCinema (OSTI)

    Pennell, Roger

    2011-04-28

    Roger Pennell, Vice President of Trait Development at Ceres, Inc., delivers a keynote address at the 5th Annual DOE JGI User Meeting on March 25, 2010

  7. Addressing the Challenges of RCCI Operation on a Light-Duty Multi-Cylinder Engine

    Broader source: Energy.gov [DOE]

    ORNL and UW collaboration in evaluating and developing RCCI operation in fully built multi-cylinder engine to address hardware, aftertreatment, and control challenges

  8. The Lessons of Practice: Domestic Policy Reform as a Way to Address...

    Open Energy Info (EERE)

    Lessons of Practice: Domestic Policy Reform as a Way to Address Climate Change Jump to: navigation, search Tool Summary LAUNCH TOOL Name: The Lessons of Practice: Domestic Policy...

  9. RE-SCHEDULED FROM JAN 22 TO JAN 28 - COLLOQUIUM: Addressing Big...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Colloquia MBG Auditorium RE-SCHEDULED FROM JAN 22 TO JAN 28 - COLLOQUIUM: Addressing Big Data Challenges in Simulation-based Science Professor Manish Parashar Rutgers...

  10. U-237: Mozilla Firefox CVE-2012-1950 Address Bar URI Spoofing...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Addthis PROBLEM: Mozilla Firefox CVE-2012-1950 Address Bar URI Spoofing Vulnerability PLATFORM: Version(s): Mozilla Firefox 6 - 12 ABSTRACT: To exploit this issue, an attacker...

  11. Recommendations to Address Power Reliability Concerns Raised as a Result of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Pending Environmental Regulations for Electric Generation Stations | Department of Energy to Address Power Reliability Concerns Raised as a Result of Pending Environmental Regulations for Electric Generation Stations Recommendations to Address Power Reliability Concerns Raised as a Result of Pending Environmental Regulations for Electric Generation Stations Memorandum from the Electricity Advisory Committee to Secretary Chu and Assistant Secretary Patricia Hoffman on recommendations to

  12. DRIVING DIRECTIONS

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    DRIVING DIRECTIONS HILTON PALACIO DEL RIO 200 South Alamo Street San Antonio, Texas 78205 (210) 222-1400 San Antonio International Airport DIRECTIONS Take Interstate 281 south to Commerce Street. Continue west on Commerce Street to Losoya Street, turn left. Losoya becomes Alamo. The Hilton Palacio del Rio is located at 200 South Alamo Street. Distance from Hotel: 8 mi. Drive Time: 20 min. From the South: -I 37 North and take Commerce Street exit -Turn left at Commerce Street -Follow Commerce

  13. RedSeal Comments on "Smart Grid RFI: Addressing Policy and Logistical

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Challenges. | Department of Energy RedSeal Comments on "Smart Grid RFI: Addressing Policy and Logistical Challenges. RedSeal Comments on "Smart Grid RFI: Addressing Policy and Logistical Challenges. RedSeal Comments on "Smart Grid RFI: Addressing Policy and Logistical Challenges. RedSeal's core technology is the ability to understand the access control of the network as a whole - not simply the behavior of a single device. RedSeal analyzes the interactions of firewalls,

  14. Secretary Chu to Give Keynote Address at World Forum on Enterprise and the

    Energy Savers [EERE]

    Environment | Department of Energy Give Keynote Address at World Forum on Enterprise and the Environment Secretary Chu to Give Keynote Address at World Forum on Enterprise and the Environment June 25, 2010 - 12:00am Addthis Washington, DC - On Sunday, June 27th, U.S. Energy Secretary Steven Chu will travel to the United Kingdom to deliver the keynote address at the World Forum on Enterprise and the Environment, hosted by the Oxford University Smith School of Enterprise and the Environment.

  15. Second Five-Year Plan to Address Uranium Contamination in the Navajo Nation

    Energy Savers [EERE]

    | Department of Energy Second Five-Year Plan to Address Uranium Contamination in the Navajo Nation Second Five-Year Plan to Address Uranium Contamination in the Navajo Nation April 3, 2015 - 4:31pm Addthis What does this project do? Goal 1. Protect human health and the environment. Federal agencies recently completed a second Five-Year Plan to address uranium contamination on the Navajo Nation, which follows a progress report on the first plan that was initiated in January 2007. Contributing

  16. Energy levels of the electrons localized over the surface of an inert film with address electrodes

    SciTech Connect (OSTI)

    Petrin, A. B.

    2013-03-15

    The problem of searching for the potential energy and the energy spectrum of the electrons localized over the surface of a thin liquid or solid inert film due to address electrodes placed under the film is considered.

  17. Oil and Gas Company Oil and Gas Company Address Place Zip Website

    Open Energy Info (EERE)

    Oil and Gas Company Address Place Zip Website Abu Dhabi National Oil Company Abu Dhabi National Oil Company Abu http www adnoc ae default aspx Al Furat Petroleum Company Al Furat...

  18. Addressing the Challenges of RCCI Operation on a Light-Duty Multi...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Challenges of RCCI Operation on a Light-Duty Multi-Cylinder Engine Addressing the Challenges of RCCI Operation on a Light-Duty Multi-Cylinder Engine ORNL and UW collaboration in ...

  19. Opportunities for Building America Research to Address Energy Upgrade Technical Challenges: HVAC, Envelope and IAQ (301)

    Broader source: Energy.gov [DOE]

    Better Buildings Residential Network Peer Exchange Call Series: Opportunities for Building America Research to Address Energy Upgrade Technical Challenges: HVAC, Envelope and IAQ (301), call slides and discussion summary.

  20. DOE to Address Small Businesses Barriers in Government Contracting at Waste Management Conference

    Broader source: Energy.gov [DOE]

    PHOENIX EM and the DOE Office of Small and Disadvantaged Business Utilization (OSDBU) are working to address barriers that hinder small businesses from competing for prime contracts for work in the Cold War cleanup program.

  1. Energy-Intensive Processes Portfolio: Addressing Key Energy Challenges Across U.S. Industry

    SciTech Connect (OSTI)

    2011-03-07

    AMO is developing advanced technologies that cut energy use and carbon emissions in some of the most energy-intensive processes within U.S. manufacturing. The brochure describes the AMO R&D projects that address these challenges.

  2. U-115: Novell GroupWise Client Address Book Processing Buffer...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    is vulnerable to an exploit where a malformed address book could cause heap memory corruption, which could lead to remote code execution under the privilege of the user that...

  3. Secretary Chu's Address to the IAEA General Conference in Vienna, Austria |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Address to the IAEA General Conference in Vienna, Austria Secretary Chu's Address to the IAEA General Conference in Vienna, Austria September 14, 2009 - 12:00am Addthis 53rd IAEA General Conference - As Prepared for Delivery Secretary Steven Chu Monday, September 14, 2009 Thank you, Madame President. Congratulations on your election as President of this Conference. I would also like to congratulate Ambassador Amano on his appointment as Director General. I pledge my

  4. President Bush Highlights Energy in the State of the Union Address |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Highlights Energy in the State of the Union Address President Bush Highlights Energy in the State of the Union Address February 3, 2005 - 10:01am Addthis "To keep our economy growing, we also need reliable supplies of affordable, environmentally responsible energy. Nearly four years ago, I submitted a comprehensive energy strategy that encourages conservation, alternative sources, a modernized electricity grid, and more production here at home -- including safe,

  5. PRESS HARD YOU ARE MAKING MULTIPLE COPIES B. MRO Name, Address, Phone No. and Fax No.

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    PRESS HARD - YOU ARE MAKING MULTIPLE COPIES B. MRO Name, Address, Phone No. and Fax No. A. Employer Name, Address, I.D. No. STEP 5A: PRIMARY SPECIMEN REPORT - COMPLETED BY TEST FACILITY NEGATIVE POSITIVE for: Marijuana Metabolite (9-THCA) 6- Acetylmorphine Methamphetamine MDMA REJECTED FOR TESTING ADULTERATED SUBSTITUTED INVALID RESULT PCP Codeine MDEA MDA Amphetamine Morphine DILUTE Cocaine Metabolite (BZE) STEP 5b: COMPLETED BY SPLIT TESTING LABORATORY X (Print) Certifying Scientist's Name

  6. Galvin Electricity Initiative DOE RFI DOE RFI 2010-23251: Addressing Policy

    Energy Savers [EERE]

    and Logistical Challenges to Smart Grid Implementation | Department of Energy Galvin Electricity Initiative DOE RFI DOE RFI 2010-23251: Addressing Policy and Logistical Challenges to Smart Grid Implementation Galvin Electricity Initiative DOE RFI DOE RFI 2010-23251: Addressing Policy and Logistical Challenges to Smart Grid Implementation The Galvin Electricity Initiative, a non-profit organization, has dedicated its resources to researching and developing both prototypes and policy reforms

  7. GridWise Alliance: Smart Grid RFI: Addressing Policy and Logistical

    Energy Savers [EERE]

    Challenges | Department of Energy GridWise Alliance: Smart Grid RFI: Addressing Policy and Logistical Challenges GridWise Alliance: Smart Grid RFI: Addressing Policy and Logistical Challenges The GridWise Alliance is a coalition of over 150 companies, organizations, and academic institutions advocating for a smart grid for a more sustainable future. We are consensus-driven and technology neutral and do not advocate for specific platforms or technologies, but, rather, for policies that will

  8. New York Independent System Operator, Smart Grid RFI: Addressing Policy and

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Logistical Challenges. | Department of Energy York Independent System Operator, Smart Grid RFI: Addressing Policy and Logistical Challenges. New York Independent System Operator, Smart Grid RFI: Addressing Policy and Logistical Challenges. In response to the Department of Energy's (DOE) Request for Information regarding smart grid implementation listed in the September 17, 2010 Federal Register, the New York Independent System Operator, Inc. (NYISO) offers the attached white paper entitled

  9. April 30, 2008; HSS/Union Working Group Meeting to address training … Meeting Summary

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    * * training. * area discussed. Center (NTC) National Training Center. * * * Conduct of Meeting. A 1. 2. 3. 4. HAMMER. HSS/UNION MEETING TO ADDRESS TRAINING DRAFT MEETING SUMMARY Introductory Remarks. Glenn Podonsky made the following points: More than a dialogue, the intent of HSS is to participate in a productive manner, to develop working relationships with the unions, to work the issues, identify actions, and institutionalize a process for addressing and resolving issues to improve worker

  10. Smart Grid Consortium, Response of New York State Smart Grid Addressing

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Policy and Logistical Challenges | Department of Energy Consortium, Response of New York State Smart Grid Addressing Policy and Logistical Challenges Smart Grid Consortium, Response of New York State Smart Grid Addressing Policy and Logistical Challenges It represents a unique public-private partnership of largely New York State utilities, authorities, universities, industrial companies, and institutions and research organizations which came together in a collaborative manner to facilitate

  11. Recent Research to Address Technical Barriers to Increased Use of Biodiesel

    Energy Savers [EERE]

    | Department of Energy Recent Research to Address Technical Barriers to Increased Use of Biodiesel Recent Research to Address Technical Barriers to Increased Use of Biodiesel 2005 Diesel Engine Emissions Reduction (DEER) Conference Presentations and Posters PDF icon 2005_deer_clark.pdf More Documents & Publications The Advanced Collaborative Emissions Study (ACES):Phase 3 Diesel Reformers for On-board Hydrogen Applications Minimizing Lubricant-Ash Requirement and Impact on Emission

  12. Natural Gas Industry Comments on Smart Grid RFI: Addressing Policy and

    Office of Environmental Management (EM)

    Logistical Challenges to Smart Grid | Department of Energy Natural Gas Industry Comments on Smart Grid RFI: Addressing Policy and Logistical Challenges to Smart Grid Natural Gas Industry Comments on Smart Grid RFI: Addressing Policy and Logistical Challenges to Smart Grid The undersigned members of the natural gas industry are pleased to submit for your consideration the following comments in response to the U.S. Department of Energy, Office of Electricity Delivery and Energy Reliability's

  13. AMENDMENT OF SOLlClTATlONlMODlFlCATlON OF CONTRACT ID PAGE I OF 2

    National Nuclear Security Administration (NNSA)

    / ' ID PAGE I OF 2 PAGES - . Albuquerque, NM 87185-5400 I Amarillo, TX 79120 I ( DE-AC04-00AL66620 10B. DATED (SEE ITEM 13) 8. NAME AND ADDRESS OF CONTRACTOR (No., street, county, state, ZIP Code) Babcock & W ~ ~ C O X Technical Services Pantex, LLC 800 Main Street Lynchburg, VA 24505 2 . AMENDMENTIMODIFICATION NO. MI50 9A. AMENDMENT OF SOLICITATION NO. 9B. DATED (SEE ITEM 11) 10A. MODIFICATION OF CONTRACTIORDER NO. Offers must acknowledge receipt of this amendment prior to the hour and date

  14. Reprogrammable read only variable threshold transistor memory with isolated addressing buffer

    DOE Patents [OSTI]

    Lodi, Robert J.

    1976-01-01

    A monolithic integrated circuit, fully decoded memory comprises a rectangular array of variable threshold field effect transistors organized into a plurality of multi-bit words. Binary address inputs to the memory are decoded by a field effect transistor decoder into a plurality of word selection lines each of which activates an address buffer circuit. Each address buffer circuit, in turn, drives a word line of the memory array. In accordance with the word line selected by the decoder the activated buffer circuit directs reading or writing voltages to the transistors comprising the memory words. All of the buffer circuits additionally are connected to a common terminal for clearing all of the memory transistors to a predetermined state by the application to the common terminal of a large magnitude voltage of a predetermined polarity. The address decoder, the buffer and the memory array, as well as control and input/output control and buffer field effect transistor circuits, are fabricated on a common substrate with means provided to isolate the substrate of the address buffer transistors from the remainder of the substrate so that the bulk clearing function of simultaneously placing all of the memory transistors into a predetermined state can be performed.

  15. Addressing environmental justice under the National Environment Policy Act at Sandia National Laboratories/New Mexico

    SciTech Connect (OSTI)

    Cohen, T.M.; Bleakly, D.R.

    1997-04-01

    Under Executive Order 12898, Federal Actions to Address Environmental Justice in Minority Populations and Low-Income Populations, the Department of Energy (DOE) and Sandia National Laboratories New Mexico (SNL) are required to identify and address, as appropriate, disproportionately high, adverse human health or environmental effects of their activities on minority and low-income populations. The National Environmental Policy Act (NEPA) also requires that environmental justice issues be identified and addressed. This presents a challenge for SNL because it is located in a culturally diverse area. Successfully addressing potential impacts is contingent upon accurately identifying them through objective analysis of demographic information. However, an effective public participation process, which is necessarily subjective, is also needed to understand the subtle nuances of diverse populations that can contribute to a potential impact, yet are not always accounted for in a strict demographic profile. Typically, there is little or no coordination between these two disparate processes. This report proposes a five-step method for reconciling these processes and uses a hypothetical case study to illustrate the method. A demographic analysis and community profile of the population within 50 miles of SNL were developed to support the environmental justice analysis process and enhance SNL`s NEPA and public involvement programs. This report focuses on developing a methodology for identifying potentially impacted populations. Environmental justice issues related to worker exposures associated with SNL activities will be addressed in a separate report.

  16. Mitsubishi iMiEV: An Electric Mini-Car in NREL's Advanced Technology Vehicle Fleet (Fact Sheet)

    SciTech Connect (OSTI)

    Not Available

    2011-10-01

    This fact sheet highlights the Mitsubishi iMiEV, an electric mini-car in the advanced technology vehicle fleet at the National Renewable Energy Laboratory (NREL). In support of the U.S. Department of Energy's fast-charging research efforts, NREL engineers are conducting charge and discharge performance testing on the vehicle. NREL's advanced technology vehicle fleet features promising technologies to increase efficiency and reduce emissions without sacrificing safety or comfort. The fleet serves as a technology showcase, helping visitors learn about innovative vehicles that are available today or are in development. Vehicles in the fleet are representative of current, advanced, prototype, and emerging technologies.

  17. Keynote Address to the American Council on Renewable Energy | Department of

    Energy Savers [EERE]

    Energy Address to the American Council on Renewable Energy Keynote Address to the American Council on Renewable Energy June 20, 2007 - 2:07pm Addthis Remarks Prepared for Energy Secretary Samuel W. Bodman Thank you, Michael, for that introduction and thank you all for coming. It is good to be in New York, back among the financial community. For those of you who don't know, when I left M.I.T - where I taught chemical engineering - to enter the business world I started out as a venture

  18. New Webinar Series to Address Climate Change Impacts in Indian Country |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Webinar Series to Address Climate Change Impacts in Indian Country New Webinar Series to Address Climate Change Impacts in Indian Country March 26, 2014 - 7:32pm Addthis On Thursday, April 3, the White House and eight federal agencies will launch a four-part webinar series focused on evaluating, assessing, and mitigating the impacts of climate change on U.S. tribal communities. The "Climate Change Impacts and Indian Country" series is sponsored by the White

  19. Report Period: EIA ID NUMBER: Appendix A: Mailing Address: Appendix B:

    Gasoline and Diesel Fuel Update (EIA)

    Report Period: EIA ID NUMBER: Appendix A: Mailing Address: Appendix B: Zip Code - Secure File Transfer option available at: - - - - Email form to: OOG.SURVEYS@eia.doe.gov Fax form to: (202) 586-9772 Email address: Oil & Gas Survey U.S. Department of Energy Ben Franklin Station PO Box 279 Washington, DC 20044-0279 Questions? Call toll free: 1-800-638-8812 1. Total Acquisitions (Enter the total volume of foreign crude oil acquired during the report month for importation into the United States.

  20. Join @Energy for the 2016 State of the Union Address | Department of Energy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    @Energy for the 2016 State of the Union Address Join @Energy for the 2016 State of the Union Address January 11, 2016 - 11:10am Addthis Join us for live coverage of the State of the Union, starting at 9PM ET on Tuesday. | Image courtesy of Carly Wilkins. Join us for live coverage of the State of the Union, starting at 9PM ET on Tuesday. | Image courtesy of Carly Wilkins. Allison Lantero Allison Lantero Digital Content Specialist, Office of Public Affairs How can I participate? Follow along with

  1. Tungsten impurity transport experiments in Alcator C-Mod to address high

    Office of Scientific and Technical Information (OSTI)

    priority research and development for ITER (Journal Article) | SciTech Connect Tungsten impurity transport experiments in Alcator C-Mod to address high priority research and development for ITER Citation Details In-Document Search Title: Tungsten impurity transport experiments in Alcator C-Mod to address high priority research and development for ITER Experiments in Alcator C-Mod tokamak plasmas in the Enhanced D-alpha H-mode regime with ITER-like mid-radius plasma density peaking and Ion

  2. Ames Laboratory to Lead New Research Effort to Address Shortages in Rare

    Energy Savers [EERE]

    Earth and Other Critical Materials | Department of Energy Laboratory to Lead New Research Effort to Address Shortages in Rare Earth and Other Critical Materials Ames Laboratory to Lead New Research Effort to Address Shortages in Rare Earth and Other Critical Materials January 9, 2013 - 12:13pm Addthis NEWS MEDIA CONTACT (202) 586-4940 WASHINGTON - The U.S. Department of Energy announced today that a team led by Ames Laboratory in Ames, Iowa, has been selected for an award of up to $120

  3. DOE Convenes Multi-stakeholder Process to Address Privacy for Data Enabled

    Office of Environmental Management (EM)

    by Smart Grid Technologies | Department of Energy Convenes Multi-stakeholder Process to Address Privacy for Data Enabled by Smart Grid Technologies DOE Convenes Multi-stakeholder Process to Address Privacy for Data Enabled by Smart Grid Technologies February 12, 2013 - 3:53pm Addthis DOE's Office of Electricy Delivery and Energy Reliability (OE) issued a notice of an open meeting on Tuesday, February 26, 2013 (9:30 a.m. to 4:30 p.m. ET) of the smart grid data privacy multi-stakeholder

  4. DOE NSF Partnership to Address Critical Challenges in Hydrogen Production from Solar Water Splitting

    Office of Energy Efficiency and Renewable Energy (EERE)

    EERE and the National Science Foundation (NSF) announce a funding opportunity in the area of renewable hydrogen technology research and development, specifically addressing discovery and development of advanced materials systems and chemical proceesses for direct photochemical and/or thermochemical water splitting for application in the solar production of hydrogen fuel.

  5. NNSA Administrator Addresses the Next Generation of Nuclear Security Professionals: Part 1

    ScienceCinema (OSTI)

    Thomas D'Agostino

    2010-09-01

    Administrator Thomas DAgostino of the National Nuclear Security Administration addressed the next generation of nuclear security professionals during the opening session of todays 2009 Department of Energy (DOE) Computational Science Graduate Fellowship Annual Conference. Administrator DAgostino discussed NNSAs role in implementing President Obamas nuclear security agenda and encouraged the computing science fellows to consider careers in nuclear security.

  6. NNSA Administrator Addresses the Next Generation of Nuclear Security Professionals: Part 2

    ScienceCinema (OSTI)

    Thomas D'Agostino

    2010-09-01

    Administrator Thomas DAgostino of the National Nuclear Security Administration addressed the next generation of nuclear security professionals during the opening session of todays 2009 Department of Energy (DOE) Computational Science Graduate Fellowship Annual Conference. Administrator DAgostino discussed NNSAs role in implementing President Obamas nuclear security agenda and encouraged the computing science fellows to consider careers in nuclear security.

  7. Challenges to be Addressed | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Challenges to be Addressed Advanced Scientific Computing Research (ASCR) ASCR Home About Research Applied Mathematics Computer Science Exascale Tools Workshop Programming Challenges Workshop Architectures I Workshop External link Architectures II Workshop External link Next Generation Networking Scientific Discovery through Advanced Computing (SciDAC) ASCR SBIR-STTR Facilities Science Highlights Benefits of ASCR Funding Opportunities Advanced Scientific Computing Advisory Committee (ASCAC)

  8. Addressing the Manufacturing Issues Associated with the use of Ceramic Materials for Diesel Engine Components.

    SciTech Connect (OSTI)

    McSpadden, SB

    2001-09-12

    This CRADA supports the objective of selecting appropriate ceramic materials for manufacturing several diesel engine components and addressing critical manufacturing issues associated with these components. Materials that were evaluated included several varieties of silicon nitride and stabilized zirconia. The critical manufacturing issues that were addressed included evaluation of the effect of grain size and the effect of the grinding process on mechanical properties, mechanical performance, reliability, and expected service life. The CRADA comprised four tasks: (1) Machining of Zirconia and Silicon Nitride Materials; (2) Mechanical Properties Characterization and Performance Testing; (3) Tribological Studies; and (4) Residual Stress Studies. Using instrumented equipment at the High Temperature Materials Laboratory (HTML) Machining and Inspection Research User Center (MIRUC), zirconia and silicon nitride materials were ground into simulated component geometries. These components were subsequently evaluated for mechanical properties, wear, and residual stress characteristics in tasks two, three, and four.

  9. Addressing the Voltage Fade Issue with Lithium-Manganese-Rich Oxide Cathode

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Materials | Department of Energy Voltage Fade Issue with Lithium-Manganese-Rich Oxide Cathode Materials Addressing the Voltage Fade Issue with Lithium-Manganese-Rich Oxide Cathode Materials 2012 DOE Hydrogen and Fuel Cells Program and Vehicle Technologies Program Annual Merit Review and Peer Evaluation Meeting PDF icon es161_burrell_2012_o.pdf More Documents & Publications Studies on Lithium Manganese Rich MNC Composite Cathodes Vehicle Technologies Office Merit Review 2014:

  10. An Information Services Algorithm to Heuristically Summarize IP Addresses for a Distributed, Hierarchical Directory Service

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    information services algorithm to heuristically summarize IP addresses for a distributed, hierarchical directory service Marcos Portnoi, Martin Swany Department of Computer and Information Sciences University of Delaware Newark, DE 19716, U.S.A. {portnoi, swany}@cis.udel.edu Jason Zurawski Internet2 Washington, DC 20036, U.S.A. zurawski@internet2.edu Abstract- A distributed, hierarchical information service for computer networks might use several service instances, located in different layers. A

  11. Jackie Chen to give keynote address at ISC High performance conference in

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Germany Jackie Chen to give keynote address at ISC High performance conference in Germany - Sandia Energy Energy Search Icon Sandia Home Locations Contact Us Employee Locator Energy & Climate Secure & Sustainable Energy Future Stationary Power Energy Conversion Efficiency Solar Energy Wind Energy Water Power Supercritical CO2 Geothermal Natural Gas Safety, Security & Resilience of the Energy Infrastructure Energy Storage Nuclear Power & Engineering Grid Modernization Battery

  12. Protocol for Addressing Induced Seismicity Associated with Enhanced Geothermal Systems (EGS)

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Draft - May 31, 2011 Protocol for Addressing Induced Seismicity Associated with Enhanced Geothermal Systems (EGS) by Ernie Majer, James Nelson, Ann Robertson-Tait, Jean Savy, and Ivan Wong PREFACE As the global demand for energy increases, the contribution from geothermal energy could be extremely large, particularly if resources developed with enhanced geothermal systems (EGS) technology are incorporated into the total energy picture. A recent study by MIT (2006) predicts that in the U.S.

  13. Chapter VII: Addressing Environmental Aspects of TS&D Infrastructure

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    36 QER Report: Energy Transmission, Storage, and Distribution Infrastructure | April 2015 Chapter VII: Addressing Environmental Aspects of TS&D Infrastructure QER Report: Energy Transmission, Storage, and Distribution Infrastructure | April 2015 8-1 Chapter VIII This chapter gives an overview of current and projected employment in and related to the energy sector and discusses programs to assist in meeting the demand for new workers going forward. The first section provides estimates of jobs

  14. UNITED STATES OF AMERICA DEPARTMENT OF ENERGY Smart Grid RFI: Addressing Policy and Logistical Challenges

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    DEPARTMENT OF ENERGY Smart Grid RFI: Addressing Policy and Logistical Challenges The National Association of Regulatory Utility Commissioners (NARUC) appreciates the opportunity to provide comments to the Department of Energy (DOE) on this Request for Information (RFI) regarding the policy and logistical challenges of the smart grid. 75 Fed. Reg. 57006 (Sept. 17, 2010). INTRODUCTION NARUC is the national organization of State commissions responsible for economic and safety regulation of

  15. Opportunities for Building America Research to Address Energy Upgrade Technical Challenges: HVAC, Envelope & IAQ (301)

    Energy Savers [EERE]

    Better Buildings Residential Network Peer Exchange Call Series: Opportunities for Building America Research to Address Energy Upgrade Technical Challenges: HVAC, Envelope & IAQ (301) July 21, 2015 Call Slides and Discussion Summary Agenda  Call Logistics and Introductions  Opening Polls  Residential Network and Peer Exchange Call Overview  Introduction to Building America Technology to Market Roadmaps  Eric Werling, Building America Program Director, DOE Building Technologies

  16. Green Building: How the Navajo Nation Can Address Renewable Energy Development at the Local Level

    Office of Environmental Management (EM)

    gov Tribal Energy Program Review Denver, CO Red Rock, New Mexico Green Building Gepetta S. Billie Graduate Intern, Tribal Energy Program Master's Candidate, Community & Regional Planning University of New Mexico How the Navajo Nation can Address Renewable Energy Development at the Local Level Work Plan & Public Involvement Implementation Assessment & Evaluation Overview Introduction Statement of Need Community Profile Conclusion 2 | Tribal Energy Program eere.energy.gov 3 | Tribal

  17. Evaluation of Multiplexed 16S rRNA Microbial Population Surveys Using Illumina MiSeq Platform (Seventh Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting 2012)

    ScienceCinema (OSTI)

    Tremblay, Julien [DOE JGI

    2013-01-25

    Julien Tremblay from DOE JGI presents "Evaluation of Multiplexed 16S rRNA Microbial Population Surveys Using Illumina MiSeq Platorm" at the 7th Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting held in June, 2012 in Santa Fe, NM.

  18. A library of MiMICs allows tagging of genes and reversible, spatial and temporal knockdown of proteins in Drosophila

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Nagarkar-Jaiswal, Sonal; Lee, Pei-Tseng; Campbell, Megan E.; Chen, Kuchuan; Anguiano-Zarate, Stephanie; Cantu Gutierrez, Manuel; Busby, Theodore; Lin, Wen-Wen; He, Yuchun; Schulze, Karen L.; et al

    2015-03-31

    Here, we document a collection of ~7434 MiMIC (Minos Mediated Integration Cassette) insertions of which 2854 are inserted in coding introns. They allowed us to create a library of 400 GFP-tagged genes. We show that 72% of internally tagged proteins are functional, and that more than 90% can be imaged in unfixed tissues. Moreover, the tagged mRNAs can be knocked down by RNAi against GFP (iGFPi), and the tagged proteins can be efficiently knocked down by deGradFP technology. The phenotypes associated with RNA and protein knockdown typically correspond to severe loss of function or null mutant phenotypes. Finally, we demonstratemore » reversible, spatial, and temporal knockdown of tagged proteins in larvae and adult flies. This new strategy and collection of strains allows unprecedented in vivo manipulations in flies for many genes. These strategies will likely extend to vertebrates.« less

  19. The following data/assumptions will better address the LLW differences between t

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    data/assumptions will better address the LLW differences between the LEU option and the LEU/Th option of Alternative 1. 1. There is 397 kg fissile ( 233 U and 235 U) in the HTGR fuel. 2. Based on past experience of LLW to Nevada National Security Site, it is expected that the maximum quantity of fissile in a Type B shipping container (CASTOR cask) will be restricted to 1 kg. To protect a 1 kg maximum, it is assumed that 900 grams would be the maximum in a CASTOR cask. Therefore, from a fissile

  20. SOFTWARE TOOLS THAT ADDRESS HAZARDOUS MATERIAL ISSUES DURING NUCLEAR FACILITY D and D

    SciTech Connect (OSTI)

    M. COURNOYER; R. GRUNDEMANN

    2001-03-01

    The 49-year-old Chemistry and Metallurgy Research (CMR) Facility is where analytical chemistry and metallurgical studies on samples of plutonium and nuclear materials are conduct in support of the Department of Energy's nuclear weapons program. The CMR Facility is expected to be decontaminated and decommissioned (D and D) over the next ten to twenty years. Over the decades, several hazardous material issues have developed that need to be address. Unstable chemicals must be properly reassigned or disposed of from the workspace during D and D operation. Materials that have critical effects that are primarily chronic in nature, carcinogens, reproductive toxin, and materials that exhibit high chronic toxicity, have unique decontamination requirements, including the decontrolling of areas where these chemicals were used. Certain types of equipment and materials that contain mercury, asbestos, lead, and polychlorinated biphenyls have special provisions that must be addressed. Utilization of commercially available software programs for addressing hazardous material issues during D and D operations such as legacy chemicals and documentation are presented. These user-friendly programs eliminate part of the tediousness associated with the complex requirements of legacy hazardous materials. A key element of this approach is having a program that inventories and tracks all hazardous materials. Without an inventory of chemicals stored in a particular location, many important questions pertinent to D and D operations can be difficult to answer. On the other hand, a well-managed inventory system can address unstable and highly toxic chemicals and hazardous material records concerns before they become an issue. Tapping into the institutional database provides a way to take advantage of the combined expertise of the institution in managing a cost effective D and D program as well as adding a quality assurance element to the program. Using laboratory requirements as a logic flow diagram, quality and cost effective methods are used to provide necessary information of programmatic, quality, and safety issues concerns. In summary, by seamlessly managing non-programmatic issues, chemical software programs allow scientists in nuclear research facilities more time to concentrate on their technical areas of interest.

  1. Addressing a single spin in diamond with a macroscopic dielectric microwave cavity

    SciTech Connect (OSTI)

    Le Floch, J.-M.; Tobar, M. E.; Bradac, C.; Nand, N.; Volz, T.; Castelletto, S.

    2014-09-29

    We present a technique for addressing single nitrogen-vacancy (NV) center spins in diamond over macroscopic distances using a tunable dielectric microwave cavity. We demonstrate optically detected magnetic resonance (ODMR) for a single negatively charged NV center (NV{sup }) in a nanodiamond (ND) located directly under the macroscopic microwave cavity. By moving the cavity relative to the ND, we record the ODMR signal as a function of position, mapping out the distribution of the cavity magnetic field along one axis. In addition, we argue that our system could be used to determine the orientation of the NV{sup } major axis in a straightforward manner.

  2. Myth-Busting2Ž: Addressing Misconceptions and Further Improving Communication During the Acquisition Process

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    MA N A G E ME N T A N D B U D G E T W A S H I N G T O N , D . C . 2 0 5 0 3 O F F I C E O F F E D E R A L May 7, 2012 P R O C U R E M E N T P O L I C Y MEMORANDUM FOR CHIEF ACQUISITION OFFICERS SENIOR PROCUREMENT EXECUTIVES CHIEF INFORMATION OFFICERS FROM: Lesley A. Field Acting Administrator for Federal Procurement Policy SUBJECT: "Myth-Busting 2": Addressing Misconceptions and Further Improving Communication During the Acquisition Process Early, frequent, and constructive engagement

  3. RE-SCHEDULED FROM JAN 22 TO JAN 28 - COLLOQUIUM: Addressing Big Data

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Challenges in Simulation-based Science | Princeton Plasma Physics Lab 8, 2014, 4:00pm to 5:30pm Colloquia MBG Auditorium RE-SCHEDULED FROM JAN 22 TO JAN 28 - COLLOQUIUM: Addressing Big Data Challenges in Simulation-based Science Professor Manish Parashar Rutgers University Presentation: PDF icon Presentation Abstract: PDF icon COLL.01.28.14.pdf COLLOQUIUM RE-SCHEDULED FROM JAN. 22 TO JAN 28 Data-related challenges are quickly dominating computational and data-enabled sciences, and are

  4. When the Internet Runs Out of Addresses, It'll be IPv6 to the Rescue! |

    Broader source: Energy.gov (indexed) [DOE]

    Department of Energy Wendy Wolfson Tsabba Communications Specialist, Lawrence Berkeley National Laboratory What does this mean for me? There are "only" 3.2 billion unique addresses available across the Internet and we are quickly approaching that limit. Network engineers have been working on a new protocol called IPv6 to solve the problem. Happy World IPv6 Day! What is IPv6 you might ask? Well, IP is the Internet Protocol. It's the way all devices on the Internet from smartphones

  5. Enabling a Highly-Scalable Global Address Space Model for Petascale Computing

    SciTech Connect (OSTI)

    Apra, Edoardo; Vetter, Jeffrey S; Yu, Weikuan

    2010-01-01

    Over the past decade, the trajectory to the petascale has been built on increased complexity and scale of the underlying parallel architectures. Meanwhile, software de- velopers have struggled to provide tools that maintain the productivity of computational science teams using these new systems. In this regard, Global Address Space (GAS) programming models provide a straightforward and easy to use addressing model, which can lead to improved produc- tivity. However, the scalability of GAS depends directly on the design and implementation of the runtime system on the target petascale distributed-memory architecture. In this paper, we describe the design, implementation, and optimization of the Aggregate Remote Memory Copy Interface (ARMCI) runtime library on the Cray XT5 2.3 PetaFLOPs computer at Oak Ridge National Laboratory. We optimized our implementation with the flow intimation technique that we have introduced in this paper. Our optimized ARMCI implementation improves scalability of both the Global Arrays (GA) programming model and a real-world chemistry application NWChem from small jobs up through 180,000 cores.

  6. COMPUTER SIMULATIONS TO ADDRESS PU-FE EUTECTICISSUE IN 3013 STORAGE VESSEL

    SciTech Connect (OSTI)

    Gupta, N; Allen Smith, A

    2007-03-06

    On November 22, 2005, the Manager of the Plutonium Finishing Plant (PFP) in Richland, WA issued an Occurrence Report involving a potential Pu-Fe eutectic failure mechanism for the stainless steel (SS) 3013 cans containing plutonium (Pu) metal. Four additional reports addressed nuclear safety concerns about the integrity of stainless steel containers holding plutonium during fire scenarios. The reports expressed a belief that the probability and consequences of container failure due to the formation of a plutonium-iron eutectic alloy had been overlooked. Simplified thermal model to address the Pu-Fe eutectic concerns using axisymmetric model similar to the models used in the 9975 SARP were performed. The model uses Rocky Flats configuration with 2 stacked Pu buttons inside a 3013 assembly. The assembly has an outer can, an inner can, and a convenience can, all stainless steel. The boundary conditions are similar to the regulatory 30 minutes HAC fire analyses. Computer simulations of the HAC fire transients lasting 4 hours of burn time show that the interface between the primary containment vessel and the Pu metal in the 9975 package will not reach Pu-Fe eutectic temperature of 400 C.

  7. Repression of miR-17-5p with elevated expression of E2F-1 and c-MYC in non-metastatic hepatocellular carcinoma and enhancement of cell growth upon reversing this expression pattern

    SciTech Connect (OSTI)

    El Tayebi, H.M.; Omar, K.; Hegy, S.; El Maghrabi, M.; El Brolosy, M.; Hosny, K.A.; Esmat, G.; Abdelaziz, A.I.

    2013-05-10

    Highlights: The oncogenic miR-17-5p is downregulated in non-metastatic hepatocellular carcinoma patients. E2F-1 and c-MYC transcripts are upregulated in non-metastatic HCC patients. miR-17-5p forced overexpression inhibited E2F-1 and c-MYC expression in HuH-7 cells. miR-17-5p mimicking increased HuH-7 cell growth, proliferation, migration and colony formation. miR-17-5p is responsible for HCC progression among the c-MYC/E2F-1/miR-17-5p triad members. -- Abstract: E2F-1, c-MYC, and miR-17-5p is a triad of two regulatory loops: a negative and a positive loop, where c-MYC induces the expression of E2F-1 that induces the expression of miR-17-5p which in turn reverses the expression of E2F-1 to close the loop. In this study, we investigated this triad for the first time in hepatocellular carcinoma (HCC), where miR-17-5p showed a significant down-regulation in 23 non-metastatic HCC biopsies compared to 10 healthy tissues; however, E2F-1 and c-MYC transcripts were markedly elevated. Forced over-expression of miR-17-5p in HuH-7 cells resulted in enhanced cell proliferation, growth, migration and clonogenicity with concomitant inhibition of E2F-1 and c-MYC transcripts expressions, while antagomirs of miR-17-5p reversed these events. In conclusion, this study revealed a unique pattern of expression for miR-17-5p in non-metastatic HCC patients in contrast to metastatic HCC patients. In addition we show that miR-17-5p is the key player among the triad that tumor growth and spread.

  8. Resonances in Coupled <mimi><mi>Kmi>-<mi>ηK> Scattering from Quantum Chromodynamics

    SciTech Connect (OSTI)

    Dudek, Jozef J.; Edwards, Robert G.; Thomas, Christopher E.; Wilson, David J.

    2014-10-01

    Using first-principles calculation within Quantum Chromodynamics, we are able to reproduce the pattern of experimental strange resonances which appear as complex singularities within coupled πK, ηK scattering amplitudes. We make use of numerical computation within the lattice discretized approach to QCD, extracting the energy dependence of scattering amplitudes through their relation- ship to the discrete spectrum of the theory in a finite-volume, which we map out in unprecedented detail.

  9. System for routing messages in a vertex symmetric network by using addresses formed from permutations of the transmission line indicees

    DOE Patents [OSTI]

    Faber, Vance (Los Alamos, NM); Moore, James W. (Los Alamos, NM)

    1992-01-01

    A network of interconnected processors is formed from a vertex symmetric graph selected from graphs .GAMMA..sub.d (k) with degree d, diameter k, and (d+1)!/(d-k+1)! processors for each d.gtoreq.k and .GAMMA..sub.d (k,-1) with degree 3-1, diameter k+1, and (d+1)!/(d-k+1)! processors for each d.gtoreq.k.gtoreq.4. Each processor has an address formed by one of the permutations from a predetermined sequence of letters chosen a selected number of letters at a time, and an extended address formed by appending to the address the remaining ones of the predetermined sequence of letters. A plurality of transmission channels is provided from each of the processors, where each processor has one less channel than the selected number of letters forming the sequence. Where a network .GAMMA..sub.d (k,-1) is provided, no processor has a channel connected to form an edge in a direction .delta..sub.1. Each of the channels has an identification number selected from the sequence of letters and connected from a first processor having a first extended address to a second processor having a second address formed from a second extended address defined by moving to the front of the first extended address the letter found in the position within the first extended address defined by the channel identification number. The second address is then formed by selecting the first elements of the second extended address corresponding to the selected number used to form the address permutations.

  10. The necessity for a practical approach to address organic emissions from cement kilns

    SciTech Connect (OSTI)

    Yonley, C.; Schreiber, B.; Kellerman, S.; Kellett, C.

    1998-12-31

    There is an inherent difficulty in monitoring organic emissions from hazardous waste combustion in the cement process. Data gathered by the EPA and the industry indicate that organic emissions at the main stack of cement kilns are principally from process characteristics and/or the desorption of organic constituents contained in the raw materials. Organic emissions are primarily based on the facility design and origin of the raw materials. One would generally conclude that organic emissions from fuels are essentially non-existent. To understand alternatives for monitoring organic emissions, this paper reviews some of the historical background behind the issue and reviews trends of characteristic organic emissions data. Based on this discussion and review, some approaches are presented to address organic emissions testing and monitoring when utilizing hazardous waste fuel in a cement kiln.

  11. Gas turbine based cogeneration facilities: Key issues to be addressed at an early design stage

    SciTech Connect (OSTI)

    Vandesteene, J.L.; De Backer, J.

    1998-07-01

    The basic design of a cogeneration facility implies much more than looking for a gas turbine generating set that matches the steam host heat demand, and making an economical evaluation of the project. Tractebel Energy Engineering (TEE) has designed, built and commissioned since the early nineties 350 MW of cogeneration facilities, mainly producing electricity and steam with natural gas fired gas turbines, which is the present most common option for industrial combined heat and power production. A standardized cogeneration design does not exist. Each facility has to be carefully adapted to the steam host's particular situation, and important technical issues have to be addressed at an early stage of plant design. Unexpected problems, expensive modifications, delays during execution of the project and possible long term operational limitations or drawbacks may result if these questions are left unanswered. This paper comments the most frequent questions on design values, required flexibility of the HRSG, reliability and backup, control system, connection to the grid

  12. In Situ Airborne Instrumentation: Addressing and Solving Measurement Problems in Ice Clouds

    SciTech Connect (OSTI)

    Baumgardner, Darrel; Kok, Greg; Avallone, L.; Bansemer, A.; Borrmann, S.; Brown, P.; Bundke, U.; Chuang, P. Y.; Cziczo, D.; Field, P.; Gallagher, M.; Gayet, J. -F.; Korolev, A.; Kraemer, M.; McFarquhar, G.; Mertes, S.; Moehler, O.; Lance, S.; Lawson, P.; Petters, M. D.; Pratt, K.; Roberts, G.; Rogers, D.; Stetzer, O.; Stith, J.; Strapp, W.; Twohy, C.; Wendisch, M.

    2012-02-01

    A meeting of 31 international experts on in situ measurements from aircraft was held to identify unresolved questions concerning ice formation and evolution in ice clouds, assess the current state of instrumentation that can address these problems, introduce emerging technology that may overcome current measurement issues and recommend future courses of action that can improve our understanding of ice cloud microphysical processes and their impact on the environment. The meeting proceedings and outcome has been described in detail in a manuscript submitted to the Bulletin of the American Meteorological Society (BAMS) on March 24, 2011. This paper is currently under review. The remainder of this summary, in the following pages, is the text of the BAMS article. A technical note that will be published by the National Center for Atmospheric Research is currently underway and is expected to be published before the end of the year.

  13. In Situ Airborne Instrumentation: Addressing and Solving Measurement Problems in Ice Clouds

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Baumgardner, Darrel; Kok, Greg; Avallone, L.; Bansemer, A.; Borrmann, S.; Brown, P.; Bundke, U.; Chuang, P. Y.; Cziczo, D.; Field, P.; et al

    2012-02-01

    A meeting of 31 international experts on in situ measurements from aircraft was held to identify unresolved questions concerning ice formation and evolution in ice clouds, assess the current state of instrumentation that can address these problems, introduce emerging technology that may overcome current measurement issues and recommend future courses of action that can improve our understanding of ice cloud microphysical processes and their impact on the environment. The meeting proceedings and outcome has been described in detail in a manuscript submitted to the Bulletin of the American Meteorological Society (BAMS) on March 24, 2011. This paper is currently undermore » review. The remainder of this summary, in the following pages, is the text of the BAMS article. A technical note that will be published by the National Center for Atmospheric Research is currently underway and is expected to be published before the end of the year.« less

  14. Strategies to Address Identified Education Gaps in the Preparation of a National Security Workforce

    SciTech Connect (OSTI)

    2008-06-30

    This report will discuss strategies available to address identified gaps and weaknesses in education efforts aimed at the preparation of a skilled and properly trained national security workforce.The need to adequately train and educate a national security workforce is at a critical juncture. Even though there are an increasing number of college graduates in the appropriate fields, many of these graduates choose to work in the private sector because of more desirable salary and benefit packages. This is contributing to an inability to fill vacant positions at NNSA resulting from high personnel turnover from the large number of retirements. Further, many of the retirees are practically irreplaceable because they are Cold War scientists that have experience and expertise with nuclear weapons.

  15. The Challenges and Potential of Nuclear Energy for Addressing Climate Change

    SciTech Connect (OSTI)

    Kim, Son H.; Edmonds, James A.

    2007-10-24

    The response to climate change and the stabilization of atmospheric greenhouse gas concentrations has major implications for the global energy system. Stabilization of atmospheric carbon dioxide (CO2) concentrations requires a peak and an indefinite decline of global CO2 emissions. Nuclear energy, along with other technologies, has the potential to contribute to the growing demand for energy without emitting CO2. Nuclear energy is of particular interest because of its global prevalence and its current significant contribution, nearly 20%, to the worlds electricity supply. We have investigated the value of nuclear energy in addressing climate change, and have explored the potential challenges for the rapid and large-scale expansion of nuclear energy as a response to climate change. The scope of this study is long-term and the modeling time frame extends out a century because the nature of nuclear energy and climate change dictate that perspective. Our results indicate that the value of the nuclear technology option for addressing climate change is denominated in trillions of dollars. Several-fold increases to the value of the nuclear option can be expected if there is limited availability of competing carbon-free technologies, particularly fossil-fuel based technologies that can capture and sequester carbon. Challenges for the expanded global use of nuclear energy include the global capacity for nuclear construction, proliferation, uranium availability, and waste disposal. While the economic costs of nuclear fuel and power are important, non-economic issues transcend the issues of costs. In this regard, advanced nuclear technologies and new vision for the global use of nuclear energy are important considerations for the future of nuclear power and climate change.

  16. DEC SW 40th Street

    Office of Energy Efficiency and Renewable Energy (EERE)

    Project outcomes: Construction of GSHP District Energy Plant. Energy/Cost Savings of HW, CHW, and DHW service (~8-9%). Data Collection to Establish Model for Geothermal District System.

  17. David Streets | Argonne National Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Lead author of UNEP black carbon and tropospheric ozone assessment report, 2011; lead author of UNECE hemispheric transport of air pollution reports, 2010, 2008; lead author of US ...

  18. POWs: Physicists on Wall Street

    SciTech Connect (OSTI)

    Derman, Emanuel

    2006-10-30

    Quantitative financial modeling seems to employ both the language and techniques of physics, but how similar are the two disciplines in theory and practice? This talk discusses the move from physics to finance, the nature of financial modeling and its deceptive similarity with theoretical physics, what it's like to work in the financial arena, and some of the open problems of interest.

  19. Microfluidic molecular assay platform for the detection of miRNAs, mRNAs, proteins, and post-translational modifications at single-cell resolution

    SciTech Connect (OSTI)

    Wu, Meiye; Singh, Anup K.

    2014-07-15

    In this study, cell signaling is a dynamic and complex process. A typical signaling pathway may begin with activation of cell surface receptors, leading to activation kinase cascade that culminates in induction of mRNA and non-coding miRNA production in the nucleus, followed by modulation of mRNA expression by miRNAs in the cytosol, and end with production of proteins in response to the signaling pathway. Signaling pathways involve proteins, miRNA, and mRNAs, along with various forms of transient post-translational modifications, and detecting each type of signaling molecule requires categorically different sample preparation methods such as Western blotting for proteins, PCR for nucleic acids, and flow cytometry for post-translational modifications. Since we know that cells in populations behave heterogeneously1, especially in the cases of stem cells, cancer, and hematopoiesis, there is need for a new technology that provides capability to detect and quantify multiple categories of signaling molecules in intact single cells to provide a comprehensive view of the cell’s physiological state. In this technical brief, we describe our microfluidic platform with a portfolio of customized molecular assays that can detect nucleic acids, proteins, and post-translational modifications in single intact cells with >95% reduction in reagent requirement in under 8 hours.

  20. Microfluidic Molecular Assay Platform for the Detection of miRNAs, mRNAs, Proteins, and Posttranslational Modifications at Single-Cell Resolution

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Wu, Meiye; Singh, Anup K.

    2014-07-15

    Cell signaling is a dynamic and complex process. A typical signaling pathway may begin with activation of cell surface receptors, leading to activation kinase cascade that culminates in induction of mRNA and non-coding miRNA production in the nucleus, followed by modulation of mRNA expression by miRNAs in the cytosol, and end with production of proteins in response to the signaling pathway. Signaling pathways involve proteins, miRNA, and mRNAs, along with various forms of transient post-translational modifications, and detecting each type of signaling molecule requires categorically different sample preparation methods such as Western blotting for proteins, PCR for nucleic acids, andmoreflow cytometry for post-translational modifications. Since we know that cells in populations behave heterogeneously1, especially in the cases of stem cells, cancer, and hematopoiesis, there is need for a new technology that provides capability to detect and quantify multiple categories of signaling molecules in intact single cells to provide a comprehensive view of the cells physiological state. In this technical brief, we describe our microfluidic platform with a portfolio of customized molecular assays that can detect nucleic acids, proteins, and post-translational modifications in single intact cells with >95% reduction in reagent requirement in under 8 hours.less

  1. Microfluidic molecular assay platform for the detection of miRNAs, mRNAs, proteins, and post-translational modifications at single-cell resolution

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Wu, Meiye; Singh, Anup K.

    2014-07-15

    In this study, cell signaling is a dynamic and complex process. A typical signaling pathway may begin with activation of cell surface receptors, leading to activation kinase cascade that culminates in induction of mRNA and non-coding miRNA production in the nucleus, followed by modulation of mRNA expression by miRNAs in the cytosol, and end with production of proteins in response to the signaling pathway. Signaling pathways involve proteins, miRNA, and mRNAs, along with various forms of transient post-translational modifications, and detecting each type of signaling molecule requires categorically different sample preparation methods such as Western blotting for proteins, PCR formore » nucleic acids, and flow cytometry for post-translational modifications. Since we know that cells in populations behave heterogeneously1, especially in the cases of stem cells, cancer, and hematopoiesis, there is need for a new technology that provides capability to detect and quantify multiple categories of signaling molecules in intact single cells to provide a comprehensive view of the cell’s physiological state. In this technical brief, we describe our microfluidic platform with a portfolio of customized molecular assays that can detect nucleic acids, proteins, and post-translational modifications in single intact cells with >95% reduction in reagent requirement in under 8 hours.« less

  2. 20% Wind Energy - Diversifying Our Energy Portfolio and Addressing Climate Change (Brochure)

    SciTech Connect (OSTI)

    Not Available

    2008-05-01

    This brochure describes the R&D efforts needed for wind energy to meet 20% of the U.S. electrical demand by 2030. In May 2008, DOE published its report, 20% Wind Energy by 2030, which presents an in-depth analysis of the potential for wind energy in the United States and outlines a potential scenario to boost wind electric generation from its current production of 16.8 gigawatts (GW) to 304 GW by 2030. According to the report, achieving 20% wind energy by 2030 could help address climate change by reducing electric sector carbon dioxide (CO2) emissions by 825 million metric tons (20% of the electric utility sector CO2 emissions if no new wind is installed by 2030), and it will enhance our nation's energy security by diversifying our electricity portfolio as wind energy is an indigenous energy source with stable prices not subject to fuel volatility. According to the report, increasing our nation's wind generation could also boost local rural economies and contribute to significant growth in manufacturing and the industry supply chain. Rural economies will benefit from a substantial increase in land use payments, tax benefits and the number of well-paying jobs created by the wind energy manufacturing, construction, and maintenance industries. Although the initial capital costs of implementing the 20% wind scenario would be higher than other generation sources, according to the report, wind energy offers lower ongoing energy costs than conventional generation power plants for operations, maintenance, and fuel. The 20% scenario could require an incremental investment of as little as $43 billion (net present value) more than a base-case no new wind scenario. This would represent less than 0.06 cent (6 one-hundredths of 1 cent) per kilowatt-hour of total generation by 2030, or roughly 50 cents per month per household. The report concludes that while achieving the 20% wind scenario is technically achievable, it will require enhanced transmission infrastructure, streamlined siting and permitting regimes, improved reliability and operability of wind systems, and increased U.S. wind manufacturing capacity. To meet these challenges, the DOE Wind Energy Program will continue to work with industry partners to increase wind energy system reliability and operability and improve manufacturing processes. The program also conducts research to address transmission and grid integration issues, to better understand wind resources, to mitigate siting and environmental issues, to provide information to industry stakeholders and policy makers, and to educate the future generations.

  3. Addressing Facility Needs for Concrete Assessment Using Ultrasonic Testing: Mid-year Report

    SciTech Connect (OSTI)

    Ulrich, Timothy J. II; Payan, Cedric; Roberts, Peter M.

    2012-03-28

    The UFD Gap Analysis to Support Extended Storage of Used Nuclear Fuel (June 30, 2011) emphasizes the need for the development of monitoring techniques and technologies for dry storage cask materials. A high priority is given to the development of 'systems for early detection of confinement boundary degradation.' This requires both new techniques for monitoring and inspection, as well as new measurable parameters to quantify mechanical degradation. The use of Nonlinear Elastic Wave Spectroscopy (NEWS) has been shown to provide sensitive parameters correlating to mechanical degradation in a wide variety of materials. Herein we report upon recent research performed to address the high priority of concrete degradation using a selection of these techniques and compare to a ASTM standard ultrasonic technique. Also reported are the near term plans to continue this research in the remaining FY and into the coming years. This research was conducted at Los Alamos National Laboratory (LANL) in the Acoustics Lab of the Geophysics group in the Earth and Environmental Sciences division, and in collaboration with the Laboratory for Nondestructive Evaluation at the University of the Mediterranean (Aix en Provence, France) and the Electrical Power Research Institute (EPRI). The objective of this research project was to determine the feasibility of using an NDE technique based on non-linear ultrasound for determining the depth and degree of microcracking in the near surface of concrete and to assess the degree of sensitivity of such technique. This objective is reached by the means of combining linear and nonlinear measurements, associated with numerical simulation. We first study the global effect of thermal damage on concrete's linear and nonlinear properties by resonance inspection techniques. We show that standard pulse wave speed techniques are not relevant to extract mechanical properties of concrete. The high sensitivity of measured nonlinearity is shown and serves as a validation tool for the rest of the study, i.e., probing the material nonlinearity at various depths through the use of Time Reversal Elastic Nonlinearity Diagnostic (TREND). The basic idea of probing the material nonlinearity at various depths by changing the frequency is validated by exhibiting a similar trend as nonlinear resonance measurements. We address at the end of this report, the potentialities of applying these procedures to real concrete structures.

  4. APRIL 30, 2008, HSS/UNION MEETING TO ADDRESS TRAINING INTEGRATED EXECUTIVE SUMMARY AND FINAL ACTION LIST

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    HSS/UNION MEETING TO ADDRESS TRAINING INTEGRATED EXECUTIVE SUMMARY AND FINAL ACTION LIST HSS and the labor unions who participated in the initial 2007 HSS Focus Group meetings agreed to a path forward in which various unions combined to form core working groups to address union identified issues by topical area. The following is a synthesis of actions/activities identified in the April 30 HSS/Union meeting to address training issues with focus in the areas of the development of DOE-wide HAMMER

  5. Architectural Framework for Addressing Legacy Waste from the Cold War - 13611

    SciTech Connect (OSTI)

    Love, Gregory A.; Glazner, Christopher G.; Steckley, Sam

    2013-07-01

    We present an architectural framework for the use of a hybrid simulation model of enterprise-wide operations used to develop system-level insight into the U.S. Department of Energy's (DOE) environmental cleanup of legacy nuclear waste at the Savannah River Site. We use this framework for quickly exploring policy and architectural options, analyzing plans, addressing management challenges and developing mitigation strategies for DOE Office of Environmental Management (EM). The socio-technical complexity of EM's mission compels the use of a qualitative approach to complement a more a quantitative discrete event modeling effort. We use this model-based analysis to pinpoint pressure and leverage points and develop a shared conceptual understanding of the problem space and platform for communication among stakeholders across the enterprise in a timely manner. This approach affords the opportunity to discuss problems using a unified conceptual perspective and is also general enough that it applies to a broad range of capital investment/production operations problems. (authors)

  6. U-165: Apple iOS Bugs Let Remote Users Execute Arbitrary Code and Spoof Address Bar URLs

    Broader source: Energy.gov [DOE]

    Two vulnerabilities were reported in Apple iOS. A remote user can cause arbitrary code to be executed on the target user's system. A remote user can spoof the address bar URL.

  7. The European Safeguards Research and Development Association Addresses Safeguards and Nonproliferation

    SciTech Connect (OSTI)

    Janssens-Maenhout, Greet; Kusumi, R.; Daures, Pascal A.; Janssens, Willem; Dickman, Deborah A.

    2010-06-16

    The renaissance of efforts to expand the use of nuclear energy requires the parallel development of a renewed and more sophisticated work force. Growth in the nuclear sector with high standard of safety, safeguards and security requires skilled staff for design, operations, inspections etc. High-quality nuclear technology educational programs are diminished from past years, and the ability of universities to attract students and to meet future staffing requirements of the nuclear industry is becoming seriously compromised. Thus, education and training in nuclear engineering and sciences is one of the cornerstones for the nuclear sector. Teaching in the nuclear field still seems strongly influenced by national history but it is time to strengthen resources and collaborate. Moreover with the current nuclear security threats it becomes critical that nuclear technology experts master the basic principles not only of safety, but also of nuclear safeguards, nonproliferation and nuclear security. In Europe the European Nuclear Education Network (ENEN) Association has established the certificate 'European Master of Science in Nuclear Engineering (EMSNE)' as the classic nuclear engineering program covering reactor operation and nuclear safety. However, it does not include courses on nonproliferation, safeguards, or dual-use technologies. The lack of education in nuclear safeguards was tackled by the European Safeguards Research and Development Association (ESARDA), through development and implementation of safeguards course modules. Since 2005 the ESARDA Working Group, called the Training and Knowledge Management Working Group, (TKMWG) has worked with the Joint Research Centre (JRC) in Ispra, Italy to organize a Nuclear Safeguards and Nonproliferation course. This five-day course is held each spring at the JRC, and continues to show increasing interest as evidenced by the positive responses of international lecturers and students. The standard set of lectures covers a broad range of subjects, including nuclear material accountancy principles, legal definitions and the regulatory base and inspection tools and techniques. This 60% core part is given by representatives from regulatory bodies (The International Atomic Energy Agency (IAEA), Institute for Radiological Protection and Nuclear Safety, Directorate General for Nuclear Energy and Transport), industry (AREVA, British Nuclear Group), and research (Stockholm University, Hamburg University, Joint Research Centre-Institute of Transuranic Elements, and Joint Research Centre-Institute for the Protection of the Citizen). The remaining part is completed with topical lectures addressed by invited lecturers, such as from Pacific Northwest National Laboratory and the IAEA addressing topics of physical protection, illicit trafficking, the Iraq case study, exercises, including satellite imagery interpretation etc. With this structure of a stable core plus a variable set of invited lectures, the course will remain sustainable and up-to-date. A syllabus provides the students a homogeneous set of information material in nuclear safeguards and nonproliferation matters at the European and international level. In this way, the ESARDA TKMWG aims to contribute to a two-fold scientific-technical and political-juridical education and training.

  8. Progress in Addressing DNFSB Recommendation 2002-1 Issues: Improving Accident Analysis Software Applications

    SciTech Connect (OSTI)

    VINCENT, ANDREW

    2005-04-25

    Defense Nuclear Facilities Safety Board (DNFSB) Recommendation 2002-1 (''Quality Assurance for Safety-Related Software'') identified a number of quality assurance issues on the use of software in Department of Energy (DOE) facilities for analyzing hazards, and designing and operating controls to prevent or mitigate potential accidents. Over the last year, DOE has begun several processes and programs as part of the Implementation Plan commitments, and in particular, has made significant progress in addressing several sets of issues particularly important in the application of software for performing hazard and accident analysis. The work discussed here demonstrates that through these actions, Software Quality Assurance (SQA) guidance and software tools are available that can be used to improve resulting safety analysis. Specifically, five of the primary actions corresponding to the commitments made in the Implementation Plan to Recommendation 2002-1 are identified and discussed in this paper. Included are the web-based DOE SQA Knowledge Portal and the Central Registry, guidance and gap analysis reports, electronic bulletin board and discussion forum, and a DOE safety software guide. These SQA products can benefit DOE safety contractors in the development of hazard and accident analysis by precluding inappropriate software applications and utilizing best practices when incorporating software results to safety basis documentation. The improvement actions discussed here mark a beginning to establishing stronger, standard-compliant programs, practices, and processes in SQA among safety software users, managers, and reviewers throughout the DOE Complex. Additional effort is needed, however, particularly in: (1) processes to add new software applications to the DOE Safety Software Toolbox; (2) improving the effectiveness of software issue communication; and (3) promoting a safety software quality assurance culture.

  9. Approach to Recover Hydrocarbons from Currently Off-Limit Areas of the Antrim Formation, MI Using Low-Impact Technologies

    SciTech Connect (OSTI)

    James Wood; William Quinlan

    2008-09-30

    The goal of this project was to develop and execute a novel drilling and completion program in the Antrim Shale near the western shoreline of Northern Michigan. The target was the gas in the Lower Antrim Formation (Upper Devonian). Another goal was to see if drilling permits could be obtained from the Michigan DNR that would allow exploitation of reserves currently off-limits to exploration. This project met both of these goals: the DNR (Michigan Department of Natural Resources) issued permits that allow drilling the shallow subsurface for exploration and production. This project obtained drilling permits for the original demonstration well AG-A-MING 4-12 HD (API: 21-009-58153-0000) and AG-A-MING 4-12 HD1 (API: 21-009-58153-0100) as well as for similar Antrim wells in Benzie County, MI, the Colfax 3-28 HD and nearby Colfax 2-28 HD which were substituted for the AG-A-MING well. This project also developed successful techniques and strategies for producing the shallow gas. In addition to the project demonstration well over 20 wells have been drilled to date into the shallow Antrim as a result of this project's findings. Further, fracture stimulation has proven to be a vital step in improving the deliverability of wells to deem them commercial. Our initial plan was very simple; the 'J-well' design. We proposed to drill a vertical or slant well 30.48 meters (100 feet) below the glacial drift, set required casing, then angle back up to tap the resource lying between the base to the drift and the conventional vertical well. The 'J'-well design was tested at Mancelona Township in Antrim County in February of 2007 with the St. Mancelona 2-12 HD 3.

  10. Arsenite evokes IL-6 secretion, autocrine regulation of STAT3 signaling, and miR-21 expression, processes involved in the EMT and malignant transformation of human bronchial epithelial cells

    SciTech Connect (OSTI)

    Luo, Fei; Xu, Yuan; Ling, Min; Zhao, Yue; Xu, Wenchao; Liang, Xiao; Jiang, Rongrong; Wang, Bairu; Bian, Qian; Liu, Qizhan

    2013-11-15

    Arsenite is an established human carcinogen, and arsenite-induced inflammation contributes to malignant transformation of cells, but the molecular mechanisms by which cancers are produced remain to be established. The present results showed that, evoked by arsenite, secretion of interleukin-6 (IL-6), a pro-inflammatory cytokine, led to the activation of STAT3, a transcription activator, and to increased levels of a microRNA, miR-21. Blocking IL-6 with anti-IL-6 antibody and inhibiting STAT3 activation reduced miR-21 expression. For human bronchial epithelial cells, cultured in the presence of anti-IL-6 antibody for 3 days, the arsenite-induced EMT and malignant transformation were reversed. Thus, IL-6, acting on STAT3 signaling, which up-regulates miR-21in an autocrine manner, contributes to the EMT induced by arsenite. These data define a link from inflammation to EMT in the arsenite-induced malignant transformation of HBE cells. This link, mediated through miRNAs, establishes a mechanism for arsenite-induced lung carcinogenesis. - Highlights: Arsenite evokes IL-6 secretion. IL-6 autocrine mediates STAT3 signaling and up-regulates miR-21expression. Inflammation is involved in arsenite-induced EMT.

  11. Addressing Uncertainty in Desigh Inputs: A Case Study of Probabilistic Settlement Evaluations for Soft Zone Collapse at SWPF

    Office of Environmental Management (EM)

    Addressing Uncertainties in Design Inputs: A Case Study of Probabilistic Settlement Evaluations for Soft Zone Collapse at SWPF Tom Houston, Greg Mertz, Carl Costantino, Michael Costantino, Andrew Maham Carl J. Costantino & Associates DOE NPH Conference Germantown, Maryland October 25-26 2011 1 CJCAssociates Introduction * Description of the SWPF Settlement Problem * Deterministic v. Probabilistic Approach to Settlement Profile Development * Analysis Approach * Parameters considered *

  12. Addressing Uncertainties in Design Inputs: A Case Study of Probabilistic Settlement Evaluations for Soft Zone Collapse at SWPF

    Broader source: Energy.gov [DOE]

    Addressing Uncertainties in Design Inputs: A Case Study of Probabilistic Settlement Evaluations for Soft Zone Collapse at SWPF Tom Houston, Greg Mertz, Carl Costantino, Michael Costantino, Andrew Maham Carl J. Costantino & Associates DOE NPH Conference Germantown, Maryland October 25-26 2011

  13. Exploring the Utilization of Complex Algal Communities to Address Algal Pond Crash and Increase Annual Biomass Production for Algal Biofuels

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Exploring the Utilization of Complex Algal Communities to Address Algal Pond Crash and Increase Annual Biomass Production for Algal Biofuels March 2014 ii Table of Contents Executive Summary ................................................................................................................................................. iii A. Topic Summary: Fostering Algal Biofuels Production through Research & Development ................................... 1 Federal Goals (Strategic U.S.

  14. Celebration of DOE's 35th Anniversary and the Secretary of Energy's Honor Awards, Keynote Address: Energy Secretary, Dr. Steven Chu

    ScienceCinema (OSTI)

    Chu, Steven (U.S. Energy Secretary)

    2012-10-18

    Dr. Steven Chu gives a keynote address marking the thirty-fifth anniversary of the Department of Energy (DOE). He highlights outstanding achievements of the Department and its scientists. Several of the Department's many Nobel Prize winners over the years are mentioned.

  15. Ecloud Build-Up Simulations for the FNAL MI for a Mixed Fill Pattern: Dependence on Peak SEY and Pulse Intensity During the Ramp

    SciTech Connect (OSTI)

    Furman, M. A.

    2010-12-11

    We present simulation results of the build-up of the electron-cloud density n{sub e} in three regions of the FNAL Main Injector (MI) for a beam fill pattern made up of 5 double booster batches followed by a 6th single batch. We vary the pulse intensity in the range N{sub t} = (2-5) x 10{sup 13}, and the beam kinetic energy in the range E{sub k} = 8-120 GeV. We assume a secondary electron emission model qualitatively corresponding to TiN, except that we let the peak value of the secondary electron yield (SEY) {delta}{sub max} vary as a free parameter in a fairly broad range. Our main conclusions are: (1) At fixed N{sub t} there is a clear threshold behavior of n{sub e} as a function of {delta}{sub max} in the range {approx} 1.1-1.3. (2) At fixed {delta}{sub max}, there is a threshold behavior of n{sub e} as a function of N{sub t} provided {delta}{sub max} is sufficiently high; the threshold value of N{sub t} is a function of the characteristics of the region being simulated. (3) The dependence on E{sub k} is weak except possibly at transition energy. Most of these results were informally presented to the relevant MI personnel in April 2010.

  16. The Office of Minority Economic Impact (MI) was established in Fiscal Year 1979 pursuant to Section 641 Title V1, Part 3 of the National Energy Conservation Policy Act (Public Law 95-619), dated November 9, 1978

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Minority Economic Impact (MI) was established in Fiscal Year 1979 pursuant to Section 641 Title V1, Part 3 of the National Energy Conservation Policy Act (Public Law 95- 619), dated November 9, 1978. The following is MI's legislative mandate. PART 3 - - MINORITY ECONOMIC IMPACT SEC. 641. MINORITY ECONOMIC IMPACT. "(a) Establishment of Office of Minority Economic Impact -- Title II of the Department of Energy Organization Act (42 U.S.C. 7131 - - 7139) is amended by adding at the end thereof

  17. Executive Order 12898: Federal Actions to Address Environmental Justice in Minority Populations and Low-Income Populations (1994)

    Office of Environmental Management (EM)

    Documents Federal Register Vol. 59, No. 32 Wednesday, February 16, 1994 Title 3- The President Executive Order 12898 of February 11, 1994 Federal Actions To Address Environmental Justice in Minority Populations and Low-Income Populations By the authority vested in me as President by the Constitution and the laws of the United States of America, it is hereby ordered as follows: Section 1-1.Implementation. 1-101. Agency Responsibilities. To the greatest extent practicable and per- mitted by law,

  18. Solar Resource Measurements in 1400 JR Lynch Street, Jackson, Mississippi: Cooperative Research and Development Final Report, CRADA Number CRD-07-254

    SciTech Connect (OSTI)

    Stoffel, T.

    2014-01-01

    Site-specific, long-term, continuous, and high-resolution measurements of solar irradiance are important for developing renewable resource data. These data are used for several research and development activities consistent with the NREL mission: Equipment will be used by Jackson State University for solar radiation data monitoring. This is a continuing effort of the Historically Black Colleges and Universities Solar Measurement Network; Provide high quality ground-truth data for satellite remote sensing validation; Support development of radiative transfer models for estimating solar irradiance from available meteorological observations; Provide solar resource information needed for technology deployment and operations. Data acquired under this agreement will be available to the public through NREL's Measurement & Instrumentation Data Center (MIDC) (www.nrel.gov/midc) or the Renewable Resource Data Center (RReDC ) (http://rredc.nrel.gov). The MIDC offers a variety of standard data display, access, and analysis tools designed to address the needs of a wide user audience (e.g., industry, academia, and government interests.

  19. AMENDMENT OF SOLICITATION/MODIFICATlON OF CONTRACT BWXT Pantex, LLC

    National Nuclear Security Administration (NNSA)

    BWXT Pantex, LLC Route 726, Mt. Athos Road Lynchburg, VA 24506 . - ~ . ~ - - Albuquerque, NM 87185-5400 I Amarillo, TX 79120 9B. DATED (SEE ITEM 11) CONTRACT ID CODE 8. NAME AND ADDRESS OF CONTRACTOR (No., street, county, state, ZIP Code) DE-AC04-00AL66620 I I IOB. DATED (SEE ITEM 13) PAGE I OF 2 PAGES 2. AMENDMENTIMODIFICATION NO. MI06 9A. AMENDMENT OF SOLICITATION NO. Offers must acknowledge receipt of this amendment prior to the hour and date specified in the solicitation as amended, by one

  20. AMENDMENT OF SOLICITATIONIMODIFICATION OF CONTRACT I '. CONTRACT ID CODE

    National Nuclear Security Administration (NNSA)

    SOLICITATIONIMODIFICATION OF CONTRACT I '. CONTRACT ID CODE BWXT Pantex, LLC Route 726, Mt. Athos Road Lynchburg, VA 24506 PAGE I OF 12 PAGES Albuquerque, NM 871 85-5400 I Amarillo, TX 79120 I I 90. DATED (SEE ITEM 1 1 ) 8. NAME AND ADDRESS OF CONTRACTOR (No., street, county, state, ZIP Code) I 10A. MODIFICATION OF CONTRACTIORDER NO. 2. AMENDMENT/MODIFICATION NO. MI67 9A. AMENDMENT OF SOLICITATION NO. I 1 DE-AC04-00AL66620 100. DATED (SEE ITEM 13) 3. EFFECTIVE DATE See Block 16C Offers must

  1. AMENDMENT OF SOLlClTATlONlMODlFlCATlON OF CONTRACT I CONTRACT ID CODE

    National Nuclear Security Administration (NNSA)

    CONTRACT ID CODE Babcock & Wilcox Technical Services Pantex, LLC 9B. DATED (SEE ITEM 11) PO Box 30020 Amarillo, T X 79120 PAGE 1 OF 2 PAGES Albuquerque, NM 87185-5400 I Amarillo, TX 79120 I I DE-AC04-00AL66620 10B. DATED (SEE ITEM 13) 8. NAME AND ADDRESS OF CONTRACTOR (No., street, county, state, ZIP Code) 2. AMENDMENTIMODIFICATION NO. MI74 9A. AMENDMENT OF SOLICITATION NO. extended. CODE I FACILITY CODE Offers must acknowledge receipt of this amendment prior to the hour and date specified

  2. AMENDMENT OF SOLlClTATlONlMODlFlCATlON OF CONTRACT I I. CONT" ID CODE

    National Nuclear Security Administration (NNSA)

    CONT" ID CODE Babcock & Wilcox Technical Services Pantex, LLC I 1 98. DATED (SEE ITEM 11) PAGE I OF 2 PAGES Albuquerque, NM 87185-5400 I Amarillo, TX 79120 PO Box 30020 Amarillo, TX 79120 8. NAME AND ADDRESS OF CONTRACTOR (No., street, county, state, ZIP Code) 10A. MODIFICATION OF CONTRACTIORDER NO. 2. AMENDMENTIMODIFICATION NO. MI64 9A. AMENDMENT OF SOLICITATION NO. DE-AC04-00AL66620 1 I IOB. DATED (SEE ITEM 13) 3. EFFECTIVE DATE See Block 16C Offers must acknowledge receipt of this

  3. AMENDMENT OF SOlLICITATION/MODIFICATlON OF CONTRACT I I. CONTRACr ID CODE

    National Nuclear Security Administration (NNSA)

    SOlLICITATION/MODIFICATlON OF CONTRACT I I. CONTRACr ID CODE BWXT Pantex, LLC Route 726, Mt. Athos Road Lynchburg, VA 24506 PAGE I OF 2 PAGES Albuquerque, NM 871 85-5400 I Amarillo, TX 79120 9B. DATED (SEE ITEM 1 1 ) 8. NAME AND ADDRESS OF CONTRACTOR (No., street, county, state, ZIP Code) DE-AC04-00AL66620 I I IOB. DATED (SEE ITEM 13) 2. AMENDMENTIMODIFICATION NO. MI41 9A. AMENDMENT OF Sol-ICITATION NO. CODE I ~ H L I L I I Y L U U ~ I I - 11. THlS ITEM ONLY APPLIES TO AMENDMENTS OF

  4. All Other Editions Are Obsolete U.S. Department of Energy Subsidy for Energy Employees' Transit Application

    Energy Savers [EERE]

    80.2 (02-93) All Other Editions Are Obsolete U.S. Department of Energy Subsidy for Energy Employees' Transit Application Name: (Last) (First) (MI) (Social Security No. Home Address: (Number/Street) (City) (State) (Zip Code) Building (FOR, GTN, etc.): Certification: I hereby certify that I am employed by U.S. Department of Energy (DOE) and am not a member of a commuter vanpool or carpool and not listed on a worksite parking permit with any Federal agency. I certify that I am eligible for a public

  5. Addressing Common Subsurface Challenges

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    geophysical and geochemical technologies quantitatively inferring subsurface evolution under current and future engineered conditions finding viable, low-risk resources...

  6. Addressing Big Data

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Big Data Challenges in Simulation-based Science Prof. Manish Parashar Rutgers University Tuesday, Jan 28, 2014 - 4:15PM MBG AUDITORIUM Refreshments at 4:00PM The PrinceTon Plasma...

  7. ARM - People Address Information

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    govAboutPerson Information About Become a User Recovery Act Mission FAQ Outreach Displays History Organization Participants Facility Statistics Forms Contacts Facility Documents ARM Management Plan (PDF, 1.3MB) Field Campaign Guidelines (PDF, 574KB) ARM Climate Research Facility Expansion Workshop (PDF, 1.46MB) Facility Activities ARM and the Recovery Act Contributions to International Polar Year Comments? We would love to hear from you! Send us a note below or call us at 1-888-ARM-DATA. Send

  8. U.S.-China Clean Energy Research Center Issues Solicitation to Address the Energy-Water Nexus

    Broader source: Energy.gov [DOE]

    Today the U.S. Department of Energy (DOE) issued a $12.5 million Funding Opportunity Announcement (FOA) for a new technical track under the U.S.-China Clean Energy Research Center (CERC) that addresses water-related aspects of energy production and use. The solicitation calls for the formation of a U.S-based consortium to work with Chinese counterparts to bolster collaborative efforts to help ensure energy, water, and environmental security and combat climate change. The consortium will be funded with $12.5 million DOE support and $12.5 million recipient cost share for a total of $25 million over the 5 year period of performance.

  9. Site Office Contracting Officer E-mail address Ames Site Office Jackie York Jacquelyn.york@ch.doe.gov

    National Nuclear Security Administration (NNSA)

    Site Office Contracting Officer E-mail address Ames Site Office Jackie York Jacquelyn.york@ch.doe.gov Argonne Site Office Jacquelyn York Jacquelyn.york@ch.doe.gov Brookhaven Site Office Evelyn Landini Jennifer Hartmann elandini@bnl.gov jhartmann@bnl.gov Idaho Site Office Paul Allen allenph@id.doe.gov Kansas City Site Office Ralph Tennant rtennant@kcp.gov Lawrence Livermore Site Office Homer Williamson homer.williamson@nnsa.doe.gov Los Alamos Site Office Barbara Romero Robert M. Poole

  10. Electrostatically focused addressable field emission array chips (AFEA's) for high-speed massively parallel maskless digital E-beam direct write lithography and scanning electron microscopy

    DOE Patents [OSTI]

    Thomas, Clarence E.; Baylor, Larry R.; Voelkl, Edgar; Simpson, Michael L.; Paulus, Michael J.; Lowndes, Douglas H.; Whealton, John H.; Whitson, John C.; Wilgen, John B.

    2002-12-24

    Systems and methods are described for addressable field emission array (AFEA) chips. A method of operating an addressable field-emission array, includes: generating a plurality of electron beams from a pluralitly of emitters that compose the addressable field-emission array; and focusing at least one of the plurality of electron beams with an on-chip electrostatic focusing stack. The systems and methods provide advantages including the avoidance of space-charge blow-up.

  11. Electrically actuatable doped polymer flakes and electrically addressable optical devices using suspensions of doped polymer flakes in a fluid host

    DOE Patents [OSTI]

    Trajkovska-Petkoska, Anka; Jacobs, Stephen D.; Marshall, Kenneth L.; Kosc, Tanya Z.

    2010-05-11

    Doped electrically actuatable (electrically addressable or switchable) polymer flakes have enhanced and controllable electric field induced motion by virtue of doping a polymer material that functions as the base flake matrix with either a distribution of insoluble dopant particles or a dopant material that is completely soluble in the base flake matrix. The base flake matrix may be a polymer liquid crystal material, and the dopants generally have higher dielectric permittivity and/or conductivity than the electrically actuatable polymer base flake matrix. The dopant distribution within the base flake matrix may be either homogeneous or non-homogeneous. In the latter case, the non-homogeneous distribution of dopant provides a dielectric permittivity and/or conductivity gradient within the body of the flakes. The dopant can also be a carbon-containing material (either soluble or insoluble in the base flake matrix) that absorbs light so as to reduce the unpolarized scattered light component reflected from the flakes, thereby enhancing the effective intensity of circularly polarized light reflected from the flakes when the flakes are oriented into a light reflecting state. Electro-optic devices contain these doped flakes suspended in a host fluid can be addressed with an applied electric field, thus controlling the orientation of the flakes between a bright reflecting state and a non-reflecting dark state.

  12. Exploring the Utilization of Complex Algal Communities to Address Algal Pond Crash and Increase Annual Biomass Production for Algal Biofuels

    SciTech Connect (OSTI)

    Hamilton, Cyd E.

    2014-03-25

    This white paper briefly reviews the research literature exploring complex algal communities as a means of increasing algal biomass production via increased tolerance, resilience, and resistance to a variety of abiotic and biotic perturbations occurring within harvesting timescales. This paper identifies what data are available and whether more research utilizing complex communities is needed to explore the potential of complex algal community stability (CACS) approach as a plausible means to increase biomass yields regardless of ecological context and resulting in decreased algal-based fuel prices by reducing operations costs. By reviewing the literature for what we do and do not know, in terms of CACS methodologies, this report will provide guidance for future research addressing pond crash phenomena.

  13. Safety and licensing issues that are being addressed by the Power Burst Facility test programs. [PWR; BWR

    SciTech Connect (OSTI)

    McCardell, R.K.; MacDonald, P.E.

    1980-01-01

    This paper presents an overview of the results of the experimental program being conducted in the Power Burst Facility and the relationship of these results to certain safety and licensing issues. The safety issues that were addressed by the Power-Cooling-Mismatch, Reactivity Initiated Accident, and Loss of Coolant Accident tests, which comprised the original test program in the Power Burst Facility, are discussed. The resolution of these safety issues based on the results of the thirty-six tests performed to date, is presented. The future resolution of safety issues identified in the new Power Burst Facility test program which consists of tests which simulate BWR and PWR operational transients, anticipated transients without scram, and severe fuel damage accidents, is described.

  14. Technical Study Addresses a Key Challenge to Harmonizing U.S. and International PV Module Standards (Fact Sheet)

    SciTech Connect (OSTI)

    Not Available

    2012-07-01

    NREL builds community and industry support by addressing concerns voiced by key standards organizations. Photovoltaic (PV) manufacturers in the United States test the safety of their products using standards developed through consensus processes. Because U.S. PV module safety standards are not aligned with international standards, manufacturers must test their modules twice - and sometimes maintain separate product lines. By meeting with standards organizations such as the Solar ABCs and Underwriters Laboratories (UL), National Renewable Energy Laboratory (NREL) leaders have worked to identify different stakeholders priorities and concerns. UL, specifically, has expressed concern that the international standards do not address all possible risks. For example, new encapsulant materials could soften at high temperatures and frameless modules could slide apart, exposing live electrical parts or allowing glass to fall on a person below. The deformation of a solid material under the influence of mechanical stresses is known as 'creep.' Current module qualification tests are limited to 85 C, whereas modules can, for short times, reach 105 C outdoors. In response to UL's concern, NREL designed and executed an experiment to compare on-sun and accelerated rates of creep for modules fabricated with various encapsulants, including some that have low melting points. Objectives were to (1) evaluate the potential for creep in outdoor exposure, (2) provide guidance on the risks and design needs with thermoplastic materials, and (3) provide a basis for modifying standards to account for materials with potential to creep. The study tested experimental materials with eight representative encapsulants in both outdoor and indoor (chamber) exposure. The study found that modules with materials that were expected to creep did so in the indoor exposure, but not in most outdoor environments and mounting configurations. The results provide a basis for defining an accelerated test needed to give confidence that the modules will not slide apart on hot days. The proposal for IEC 61730 Part 1 exposes modules for 200 hours to a temperature between 105 C and 110 C. NREL is collaborating with UL representatives, and U.S. and international standards appear to be closer to harmonization.

  15. Photoelectron imaging and theoretical study on the structure and chemical binding of the mixed-ligand M(I) complexes, [HMSH]{sup ?} (M = Cu, Ag, and Au)

    SciTech Connect (OSTI)

    Qin, Zhengbo; Liu, Zhiling; Cong, Ran; Xie, Hua; Tang, Zichao, E-mail: zctang@dicp.ac.cn, E-mail: fanhj@dicp.ac.cn; Fan, Hongjun, E-mail: zctang@dicp.ac.cn, E-mail: fanhj@dicp.ac.cn [State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023 (China)] [State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023 (China)

    2014-03-21

    We have reported a combined photoelectron imaging and theoretical study on gaseous mixed-ligand M(I) complexes of [HMSH]{sup ?} (M = Cu, Ag, and Au). With the aid of Franck-Condon simulations, vibrationally resolved photoelectron spectra yield accurate electron affinities of 3.269(6), 3.669(10), and 3.591(6) eV for [HCuSH], [HAgSH], and [HAuSH], respectively. And low-frequency modes are observed: 368(12) cm{sup ?1} for [HCuSH], 286(12) cm{sup ?1} for [HAgSH], and 327(12) cm{sup ?1} for [HAuSH], respectively. Extensive theoretical calculations are performed to aid in the spectral assignments and the calculated values agree well with the experimental observations. Although the S and H atoms have little discrepancy in electronegativity (2.20 for H and 2.54 for S), distinct bonding properties are demonstrated between HM and MS bond. It is revealed that there exists significant ionic bonding between MS in [HMSH]{sup ?} (M = Cu, Ag, and Au), while a gradual transition from ionic behavior between HCu in [HCuSH]{sup ?} to quite strong covalent bonding between HAu in [HAuSH]{sup ?}, supported by a variety of chemical bonding analyses.

  16. Improved Measurement of the <mi>?>?<mi mathvariant='normal'>emi>?> Branching Ratio

    SciTech Connect (OSTI)

    Aguilar-Arevalo, A.; Aoki, M.; Blecher, M.; Britton, D. I.; Bryman, D. A.; vom Bruch, D.; Chen, S.; Comfort, J.; Ding, M.; Doria, L.; Cuen-Rochin, S.; Gumplinger, P.; Hussein, A.; Igarashi, Y.; Ito, S.; Kettell, S. H.; Kurchaninov, L.; Littenberg, L. S.; Malbrunot, C.; Mischke, R. E.; Numao, T.; Protopopescu, D.; Sher, A.; Sullivan, T.; Vavilov, D.; Yamada, K.

    2015-08-01

    A new measurement of the branching ratio Re/?=?(?+ ? e+? + ?+ ? e+??)/?(?+ ? ?+? + ?+??+??) resulted in Rexpe/?=[1.23440.0023(stat)0.0019(syst)] x 10-4. This is in agreement with the standard model prediction and improves the test of electron-muon universality to the level of 0.1%.

  17. Northeast Biofuels Collaborative | Open Energy Information

    Open Energy Info (EERE)

    Biofuels Collaborative Jump to: navigation, search Logo: Northeast Biofuels Collaborative Name: Northeast Biofuels Collaborative Address: 101 Tremont Street Place: Boston,...

  18. Energy Frontier Research Centers: Helping Win the Energy Innovation Race (2011 EFRC Summit Keynote Address, Secretary of Energy Chu)

    ScienceCinema (OSTI)

    Chu, Steven (DOE Secretary of Energy)

    2012-03-14

    Secretary of Energy Steven Chu gave the keynote address at the 2011 EFRC Summit and Forum. In his talk, Secretary Chu highlighted the need to "unleash America's science and research community" to achieve energy breakthroughs. The 2011 EFRC Summit and Forum brought together the EFRC community and science and policy leaders from universities, national laboratories, industry and government to discuss "Science for our Nation's Energy Future." In August 2009, the Office of Science established 46 Energy Frontier Research Centers. The EFRCs are collaborative research efforts intended to accelerate high-risk, high-reward fundamental research, the scientific basis for transformative energy technologies of the future. These Centers involve universities, national laboratories, nonprofit organizations, and for-profit firms, singly or in partnerships, selected by scientific peer review. They are funded at $2 to $5 million per year for a total planned DOE commitment of $777 million over the initial five-year award period, pending Congressional appropriations. These integrated, multi-investigator Centers are conducting fundamental research focusing on one or more of several ?grand challenges? and use-inspired ?basic research needs? recently identified in major strategic planning efforts by the scientific community. The purpose of the EFRCs is to integrate the talents and expertise of leading scientists in a setting designed to accelerate research that transforms the future of energy and the environment.

  19. Addressing the Federal-State-Local Interface Issues During a Catastrophic Event Such as an Anthrax Attack

    SciTech Connect (OSTI)

    Stein, Steven L.; Lesperance, Ann M.; Upton, Jaki F.

    2010-02-01

    On October 9, 2008, federal, state and local policy makers, emergency managers, and medical and public health officials convened in Seattle, Washington, for a workshop on Addressing the Federal-State-Local Interface Issues During a Catastrophic Event Such as an Anthrax Attack. The day-long symposium was aimed at generating a dialogue about recovery and restoration through a discussion of the associated challenges that impact entire communities, including people, infrastructure, and critical systems. The Principal Federal Official (PFO) provided an overview of the role of the PFO in a catastrophic event. A high-level summary of an anthrax scenario was presented. The remainder of the day was focused on interactive discussions among federal, state and local emergency management experts in the areas of: Decision-making, prioritization, and command and control Public health/medical services Community resiliency and continuity of government. Key topics and issues that resulted from discussions included: Local representation in the Joint Field Office (JFO) JFO transition to the Long-Term Recovery Office Process for prioritization of needs Process for regional coordination Prioritization - process and federal/military intervention Allocation of limited resources Re-entry decision and consistency Importance of maintaining a healthy hospital system Need for a process to establish a consensus on when it is safe to re-enter. This needs to be across all jurisdictions including the military. Insurance coverage for both private businesses and individuals Interaction between the government and industry. The symposium was sponsored by the Interagency Biological Restoration Demonstration, a collaborative regional program jointly funded by the U.S. Department of Homeland Security and the U.S. Department of Defense. To aid the programs efforts and inform the development of blueprint for recovery from a biological incident, this report presents the key issues identified at the symposium.

  20. Comparative proteomic analysis of Desulfotomaculum reducens MI-1: Insights into the metabolic versatility of a gram-positive sulfate- and metal-reducing bacterium

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Otwell, Anne E.; Callister, Stephen J.; Zink, Erika M.; Smith, Richard D.; Richardson, Ruth E.

    2016-02-19

    In this study, the proteomes of the metabolically versatile and poorly characterized Gram-positive bacterium Desulfotomaculum reducens MI-1 were compared across four cultivation conditions including sulfate reduction, soluble Fe(III) reduction, insoluble Fe(III) reduction, and pyruvate fermentation. Collectively across conditions, we observed at high confidence ~38% of genome-encoded proteins. Here, we focus on proteins that display significant differential abundance on conditions tested. To the best of our knowledge, this is the first full-proteome study focused on a Gram-positive organism cultivated either on sulfate or metal-reducing conditions. Several proteins with uncharacterized function encoded within heterodisulfide reductase (hdr)-containing loci were upregulated on either sulfatemore » (Dred_0633-4, Dred_0689-90, and Dred_1325-30) or Fe(III)-citrate-reducing conditions (Dred_0432-3 and Dred_1778-84). Two of these hdr-containing loci display homology to recently described flavin-based electron bifurcation (FBEB) pathways (Dred_1325-30 and Dred_1778-84). Additionally, we propose that a cluster of proteins, which is homologous to a described FBEB lactate dehydrogenase (LDH) complex, is performing lactate oxidation in D. reducens (Dred_0367-9). Analysis of the putative sulfate reduction machinery in D. reducens revealed that most of these proteins are constitutively expressed across cultivation conditions tested. In addition, peptides from the single multiheme c-type cytochrome (MHC) in the genome were exclusively observed on the insoluble Fe(III) condition, suggesting that this MHC may play a role in reduction of insoluble metals.« less