National Library of Energy BETA

Sample records for mi stop time

  1. Real-time sub-<mi>Å>ngstrom...

    Office of Scientific and Technical Information (OSTI)

    Real-time sub-<mi>>ngstrom imaging of reversible and irreversible conformations in rhodium catalysts and graphene Kisielowski, Christian; Wang,...

  2. The New York Times covers "National Labs Race to Stop Iran"

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The New York Times covers "National Labs Race to Stop Iran" The New York Times covers "National Labs Race to Stop Iran" Given the stakes in the sensitive negotiations with Iran,...

  3. Time Consistent Risk Measure Under Stopping Time Framework ...

    E-Print Network [OSTI]

    2015-02-13

    to the stochastic volatility of security markets and constantly change of economic and financial information, the earliest target reaching time is random, it then ...

  4. The Sequential Action of miR156 and miR172 Regulates Developmental Timing

    E-Print Network [OSTI]

    Weigel, Detlef

    Planck Institute for Developmental Biology, D-72076 Tu¨ bingen, Germany *Correspondence: spoethig@sas elegans (Moss, 2007; Rougvie, 2005) and plants (Ba¨ urle and Dean, 2006; Chuck and Hake, 2005; Poethig in Moss, 2007; Pasquinelli and Ruvkun, 2002; Rougvie, 2005). These were the first miRNAs to be discovered

  5. Last First MI CRN Course ID Credit Audit? Days Time

    E-Print Network [OSTI]

    Karsai, Istvan

    Registration Worksheet ON OR AFTER YOUR ASSIGNED REGISTRATION APPOINTMENT TIME... Go to https://goldlink.etsu.edu REGISTRAR'S OFFICE (HELP-LINE) HOURS: MONDAY - FRIDAY (8:00 AM - 4:30 PM) REGISTRAR HOME PAGE: www.etsu posted by the Bursars office. If you decide not to attend ETSU, you must drop your courses before

  6. 108 OPTIMAL STOPPING TIME 4.4. Cost functions. The cost function g(x) gives the price you must

    E-Print Network [OSTI]

    Igusa, Kiyoshi

    108 OPTIMAL STOPPING TIME 4.4. Cost functions. The cost function g(x) gives the price you must pay. But your cost to play to that point was cost = g(X0) + g(X1) + · · · + g(XT-1) = T-1 j=0 g(Xj) So, your net the equation: v(x) = max(f(x), (Pv)(x) - g(x)) Proof: In state x you should either stop or continue. (1) If you

  7. New results on the stopping time behaviour of the Collatz 3x + 1 function

    E-Print Network [OSTI]

    Mike Winkler

    2015-03-29

    Let $\\sigma_n=\\lfloor1+n\\cdot\\log_23\\rfloor$. For the Collatz 3x + 1 function exists for each $n\\in\\mathbb{N}$ a set of different residue classes $(mod\\ 2^{\\sigma_n})$ of starting numbers $s$ with finite stopping time $\\sigma(s)=\\sigma_n$. Let $z_n$ be the number of these residue classes for each $n\\geq0$ as listed in the OEIS as A100982. It is conjectured that for each $n\\geq4$ the value of $z_n$ is given by the formula \\begin{align*} z_n=\\binom{\\big\\lfloor\\frac{5(n-2)}{3}\\big\\rfloor}{n-2}-\\sum_{i=2}^{n-1}\\binom{\\big\\lfloor\\frac{3(n-i)+\\delta}{2}\\big\\rfloor}{n-i}\\cdot z_i, \\end{align*} where $\\delta\\in\\mathbb{Z}$ assumes different values within the sum at intervals of 5 or 6 terms. This allows to create an iterative algorithm which generates $z_n$ for each $n>12$. This has been proved for each $n\\leq10000$. The number $z_{10000}$ has 4527 digits.

  8. A High Resolution, Multi-stop, Time-to-Digital Converter for Nuclear Time-of-Flight Measurements

    SciTech Connect (OSTI)

    D. F. Spencer; J. Cole; M. Drigert; R. Aryaeinejad

    2006-01-01

    A high-resolution, multi-stop, time-to-digital converter (TDC) was designed and developed to precisely measure the times-of-flight (TOF) of incident neutrons responsible for induced fission and capture reactions on actinide targets. The minimum time resolution is ±1 ns. The TDC design was implemented into a single, dual-wide CAMAC module. The CAMAC bus is used for command and control as well as an alternative data output. A high-speed ECL interface, compatible with LeCroy FERA modules, was also provided for the principle data output path. An Actel high-speed field programmable gate array (FPGA) chip was incorporated with an external oscillator and an internal multiple clock phasing system. This device implemented the majority of the high-speed register functions, the state machine for the FERA interface, and the high-speed counting circuit used for the TDC conversion. An external microcontroller was used to monitor and control system-level changes. In this work we discuss the performance of this TDC module as well as its application.

  9. Labs Race to Stop Iran"

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    New York Times covers "National Labs Race to Stop Iran" May 15, 2015 National labs race to stop Iran Given the stakes in the sensitive negotiations with Iran, the labs would...

  10. The New York Times covers "National Labs Race to Stop Iran"

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home RoomPreservationBio-Inspired Solar FuelTechnologyTel: Name:Department ofThe DOEThe New York Times

  11. 114 OPTIMAL STOPPING TIME 4.5. discounted payoff. Here we assume that the payoff is losing

    E-Print Network [OSTI]

    Igusa, Kiyoshi

    . If there is no cost, the value function will satisfy the equation v(x) = max(f(x), (Pv)(x)) Again there is a recursive, you should play even if there is a cost of g(x) = 2. If X0 = 3 then you get f(x) = 8 if you stop

  12. 6 Year Graduation Model for Full-time Freshmen (Non-SEEK) Students * Students labeled `Not Enrolled' in the charts are either stop outs (may return to QC after a semester off) or drop outs or transfers in this study.

    E-Print Network [OSTI]

    Johnson Jr.,, Ray

    6 Year Graduation Model for Full-time Freshmen (Non-SEEK) Students * Students labeled `Not Enrolled' in the charts are either stop outs (may return to QC after a semester off) or drop outs or transfers Graduation Model for Full-time Transfer Students * Students labeled `Not Enrolled' in the charts are either

  13. Search for long-lived stopped R-hadrons decaying out of time with pp collisions using the ATLAS detector

    E-Print Network [OSTI]

    Taylor, Frank E.

    An updated search is performed for gluino, top squark, or bottom squark R-hadrons that have come to rest within the ATLAS calorimeter, and decay at some later time to hadronic jets and a neutralino, using 5.0 and ...

  14. NONPROFIT ORG DETROIT, MI

    E-Print Network [OSTI]

    Berdichevsky, Victor

    NONPROFIT ORG US POSTAGE PAID DETROIT, MI PERMIT NO 3844 College of Engineering Wayne State University 5050 Anthony Wayne Drive Room 1153 · Detroit, MI 48202 Phone (313) 577-3780 · Fax (313) 577, Wayne State University 5050 Anthony Wayne Drive Detroit, MI 48202 My first assignment for Ex

  15. Sneaky light stop

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Eifert, Till; Nachman, Benjamin

    2015-02-20

    A light supersymmetric top quark partner (stop) with a mass nearly degenerate with that of the standard model (SM) top quark can evade direct searches. The precise measurement of SM top properties such as the cross-section has been suggested to give a handle for this ‘stealth stop’ scenario. We present an estimate of the potential impact a light stop may have on top quark mass measurements. The results indicate that certain light stop models may induce a bias of up to a few GeV, and that this effect can hide the shift in, and hence sensitivity from, cross-section measurements. Duemore »to the different initial states, the size of the bias is slightly different between the LHC and the Tevatron. The studies make some simplifying assumptions for the top quark measurement technique, and are based on truth-level samples.« less

  16. Quick stop device

    DOE Patents [OSTI]

    Hipwell, Roger L. (35 Hounds Ditch La., Duxbury, MA 02332); Hazelton, Andrew J. (3877 Army St., San Francisco, CA 94131)

    1996-01-01

    A quick stop device for abruptly interrupting the cutting of a workpiece by a cutter is disclosed. The quick stop device employs an outer housing connected to an inner workpiece holder by at least one shear pin. The outer housing includes an appropriate shank designed to be received in the spindle of a machine, such as a machine tool. A cutter, such as a drill bit, is mounted in a stationary position and the workpiece, mounted to the workpiece holder, is rotated during engagement with the cutter. A trigger system includes at least one spring loaded punch disposed for movement into engagement with the workpiece holder to abruptly stop rotation of the workpiece holder. This action shears the shear pin and permits continued rotation of the spindle and outer housing without substantially disturbing the chip root formed during cutting.

  17. Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells

    SciTech Connect (OSTI)

    Vrba, Lukas; Jensen, Taylor J.; Garbe, James C.; Heimark, Ronald L.; Cress, Anne E.; Dickinson, Sally; Stampfer, Martha R.; Futscher, Bernard W.

    2009-12-23

    BACKGROUND: The microRNA-200 family participates in the maintenance of an epithelial phenotype and loss of its expression can result in epithelial to mesenchymal transition (EMT). Furthermore, the loss of expression of miR-200 family members is linked to an aggressive cancer phenotype. Regulation of the miR-200 family expression in normal and cancer cells is not fully understood. METHODOLOGY/ PRINCIPAL FINDINGS: Epigenetic mechanisms participate in the control of miR-200c and miR-141 expression in both normal and cancer cells. A CpG island near the predicted mir-200c/mir-141 transcription start site shows a striking correlation between miR-200c and miR-141 expression and DNA methylation in both normal and cancer cells, as determined by MassARRAY technology. The CpG island is unmethylated in human miR-200/miR-141 expressing epithelial cells and in miR-200c/miR-141 positive tumor cells. The CpG island is heavily methylated in human miR-200c/miR-141 negative fibroblasts and miR-200c/miR-141 negative tumor cells. Mouse cells show a similar inverse correlation between DNA methylation and miR-200c expression. Enrichment of permissive histone modifications, H3 acetylation and H3K4 trimethylation, is seen in normal miR-200c/miR-141-positive epithelial cells, as determined by chromatin immunoprecipitation coupled to real-time PCR. In contrast, repressive H3K9 dimethylation marks are present in normal miR-200c/miR-141-negative fibroblasts and miR-200c/miR-141 negative cancer cells and the permissive histone modifications are absent. The epigenetic modifier drug, 5-aza-2'-deoxycytidine, reactivates miR-200c/miR-141 expression showing that epigenetic mechanisms play a functional role in their transcriptional control. CONCLUSIONS/ SIGNIFICANCE: We report that DNA methylation plays a role in the normal cell type-specific expression of miR-200c and miR-141 and this role appears evolutionarily conserved, since similar results were obtained in mouse. Aberrant DNA methylation of the miR-200c/141 CpG island is closely linked to their inappropriate silencing in cancer cells. Since the miR-200c cluster plays a significant role in EMT, our results suggest an important role for DNA methylation in the control of phenotypic conversions in normal cells.

  18. Impact of Impulse Stops on Pedestrian Flow

    E-Print Network [OSTI]

    Kwak, Jaeyoung; Luttinen, Tapio; Kosonen, Iisakki

    2015-01-01

    We numerically study the impact of impulse stops on pedestrian flow for a straight corridor with multiple attractions. The impulse stop is simulated by the switching behavior model, a function of the social influence strength and the number of attendees near the attraction. When the pedestrian influx is low, one can observe a stable flow where attendees make a complete stop at an attraction and then leave the attraction after a certain amount of time. When the pedestrian influx is high, an unstable flow is observed for strong social influence. In the unstable flow, attendees near the attraction are crowded out from the clusters by others due to the interpersonal repulsion. The expelled pedestrians impede the pedestrian traffic between the left and right boundaries of the corridor. These collective patterns of pedestrian flow are summarized in a schematic phase diagram.

  19. The following is an explanation about calculating the "No Stop Time": Starting out with the basic Haldane equation (keep in mind that

    E-Print Network [OSTI]

    Haase, Markus

    pressure is the ambient pressure minus the water vapor pressure (Buhlmann value) times the fraction or descents): P = Po + (Pi - Po)(1 - e^-kt) which states that P, the final partial pressure in a given compartment (as a function of time), will be the initital partial pressure, Po, plus (or minus

  20. MI Gap Clearing Kicker Magnet Design Review

    SciTech Connect (OSTI)

    Jensen, Chris; /Fermilab

    2008-10-01

    The kicker system requirements were originally conceived for the NOvA project. NOvA is a neutrino experiment located in Minnesota. To achieve the desired neutrino flux several upgrades are required to the accelerator complex. The Recycler will be used as a proton pre-injector for the Main Injector (MI). As the Recycler is the same size as the MI, it is possible to do a single turn fill ({approx}11 {micro}sec), minimizing the proton injection time in the MI cycle and maximizing the protons on target. The Recycler can then be filled with beam while the MI is ramping to extract beam to the target. To do this requires two new transfer lines. The existing Recycler injection line was designed for 10{pi} pbar beams, not the 20{pi} proton beams we anticipate from the Booster. The existing Recycler extraction line allows for proton injection through the MI, while we want direct injection from the Booster. These two lines will be decommissioned. The new injection line from the MI8 line into the Recycler will start at 848 and end with injection kickers at RR104. The new extraction line in the RR30 straight section will start with a new extraction kicker at RR232 and end with new MI injection kickers at MI308. Finally, to reduce beam loss activation in the enclosure, a new gap clearing kicker will be used to extract uncaptured beam created during the slip stack injection process down the existing dump line. It was suggested that the MI could benefit from this type of system immediately. This led to the early installation of the gap clearing system in the MI, followed by moving the system to Recycler during NOvA. The specifications also changed during this process. Initially the rise and fall time requirements were 38 ns and the field stability was {+-}1%. The 38 ns is based on having a gap of 2 RF buckets between injections. (There are 84 RF buckets that can be filled from the Booster for each injection, but 82 would be filled with beam. MI and Recycler contain 588 RF buckets.) A rough cost/benefit analysis showed that increasing the number of empty buckets to 3 decreased the kicker system cost by {approx}30%. This could be done while not extending the running time since this is only a 1% reduction in protons per pulse, hence the rise and fall time are now 57 ns. Additionally, the {+-}1% tolerance would have required a fast correction kicker while {+-}3% could be achieved without this kicker. The loosened tolerance was based on experience on wide band damping systems in the MI. A higher power wideband damping system is a better use of the resources as it can be used to correct for multiple sources of emittance growth. Finally, with the use of this system for MI instead of Recycler, the required strength grew from 1.2 mrad to 1.7 mrad. The final requirements for this kicker are listed.

  1. Stop City IntersectionStop # Van Name Arrive Depart Van Stops, Times, & Fees

    E-Print Network [OSTI]

    Mullins, Dyche

    .88Active 7.6DENTAL6:40 CONCORD 59Near Pleasant Hill Bart Station2120.01 CONCORD 12120 7:55 5:05 $195:30 CONCORD 59Near Pleasant Hill Bart Station2120.01 CONCORD 12120 7:55 5:05 $195.12Active 8.05P, LH6:50 DALY, MTZ6:50 ELK GROVE 203LAGUNA & FRANKLIN BLVD.2225.01 ELK GROVE2225 6:15 3:20 $356.40Active 6.4MB

  2. Fact #853 December 29, 2014 Stop/Start Technology is in nearly 5% of All New Light Vehicles Produced

    Broader source: Energy.gov [DOE]

    Stop/Start technology improves fuel economy by reducing engine idle time. As a vehicle slows to a stop, the engine is shut down but then immediately restarts when the break pedal is released so...

  3. Stopping power: Effect of the projectile deceleration

    SciTech Connect (OSTI)

    Kompaneets, Roman Ivlev, Alexei V.; Morfill, Gregor E.

    2014-11-15

    The stopping force is the force exerted on the projectile by its wake. Since the wake does not instantly adjust to the projectile velocity, the stopping force should be affected by the projectile deceleration caused by the stopping force itself. We address this effect by deriving the corresponding correction to the stopping force in the cold plasma approximation. By using the derived expression, we estimate that if the projectile is an ion passing through an electron-proton plasma, the correction is small when the stopping force is due to the plasma electrons, but can be significant when the stopping force is due to the protons.

  4. Interaction between two stopped light pulses

    SciTech Connect (OSTI)

    Chen, Yi-Hsin, E-mail: yhchen920@gmail.com; Lee, Meng-Jung, E-mail: yhchen920@gmail.com; Hung, Weilun, E-mail: yhchen920@gmail.com; Yu, Ite A., E-mail: yu@phys.nthu.edu.tw [Department of Physics and Frontier Research Center on Fundamental and Applied Sciences of Matters, National Tsing Hua University, Hsinchu 30013, Taiwan (China); Chen, Ying-Cheng [Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei 10617, Taiwan and Department of Physics and Frontier Research Center on Fundamental and Applied Sciences of Matters, National Tsing Hua University, Hsinchu 30013, Taiwan (China); Chen, Yong-Fan [Department of Physics, National Cheng Kung University, Tainan 70101, Taiwan (China)

    2014-03-05

    The efficiency of a nonlinear optical process is proportional to the interaction time. We report a scheme of all-optical switching based on two motionless light pulses via the effect of electromagnetically induced transparency. One pulse was stopped as the stationary light pulse (SLP) and the other was stopped as stored light. The time of their interaction via the medium can be prolonged and, hence, the optical nonlinearity is greatly enhanced. Using a large optical density (OD) of 190, we achieved a very long interaction time of 6.9 ?s. This can be analogous to the scheme of trapping light pulses by an optical cavity with a Q factor of 8×10{sup 9}. With the approach of using moving light pulses in the best situation, a switch can only be activated at 2 photons per atomic absorption cross section. With the approach of employing a SLP and a stored light pulse, a switch at only 0.56 photons was achieved and the efficiency is significantly improved. Moreover, the simulation results are in good agreement with the experimental data and show that the efficiency can be further improved by increasing the OD of the medium. Our work advances the technology in quantum information manipulation utilizing photons.

  5. Apparatus for stopping a vehicle

    DOE Patents [OSTI]

    Wattenburg, Willard H. (Walnut Creek, CA); McCallen, David B. (Livermore, CA)

    2007-03-20

    An apparatus for externally controlling one or more brakes on a vehicle having a pressurized fluid braking system. The apparatus can include a pressurizable vessel that is adapted for fluid-tight coupling to the braking system. Impact to the rear of the vehicle by a pursuit vehicle, shooting a target mounted on the vehicle or sending a signal from a remote control can all result in the fluid pressures in the braking system of the vehicle being modified so that the vehicle is stopped and rendered temporarily inoperable. A control device can also be provided in the driver's compartment of the vehicle for similarly rendering the vehicle inoperable. A driver or hijacker of the vehicle preferably cannot overcome the stopping action from the driver's compartment.

  6. Stop Fee Pick-up Place Bus Leaves By Stop 1 $50 Ontario Love's Travel Stop and Country Store, 1041 NW Washington Ave 7:00 AM, MDT

    E-Print Network [OSTI]

    Tullos, Desiree

    Stop Fee Pick-up Place Bus Leaves By Stop 1 $50 Ontario Love's Travel Stop and Country Store, 1041 Ave 5:30 PM Stop 4 Ontario Love's Travel Stop and Country Store, 1041 NW Washington Ave 8:30 PM, MDT ONTARIO ROUTE 1 Boise Winnemucca 2:30 PM ** 45 minute lunch stop prior to leaving Bend Take Home Saturday

  7. TECH pulse Light stopped for a minute

    E-Print Network [OSTI]

    Rotter, Stefan

    TECH pulse · Light stopped for a minute DARMSTADT, Germany - At 186,000 miles per second, the speed of light is unparalleled, so slowing it down is a for- midable challenge - and stopping it seems impossible. But physicists in Germany report using a glasslike crystal to stop light for about one minute, which could have

  8. Radiosensitizing Effects of Ectopic miR-101 on Non-Small-Cell Lung Cancer Cells Depend on the Endogenous miR-101 Level

    SciTech Connect (OSTI)

    Chen, Susie; Wang Hongyan; Ng, Wooi Loon; Curran, Walter J.; Wang Ya

    2011-12-01

    Purpose: Previously, we showed that ectopic miR-101 could sensitize human tumor cells to radiation by targeting ATM and DNA-PK catalytic subunit (DNA-PKcs) to inhibit DNA repair, as the endogenous miR-101 levels are low in tumors in general. However, the heterogeneity of human cancers may result in an exception. The purpose of this study was to test the hypothesis that a few tumor cell lines with a high level of endogenous miR-101 would prove less response to ectopic miR-101. Methods and Materials: Fourteeen non-small-cell lung cancer (NSCLC) cell lines and one immortalized non-malignant lung epithelial cell line (NL20) were used for comparing endogenous miR-101 levels by real-time reverse transcription-polymerase chain reaction. Based on the different miR-101 levels, four cell lines with different miR-101 levels were chosen for transfection with a green fluorescent protein-lentiviral plasmid encoding miR-101. The target protein levels were measured by using Western blotting. The radiosensitizing effects of ectopic miR-101 on these NSCLC cell lines were determined by a clonogenic assay and xenograft mouse model. Results: The endogenous miR-101 level was similar or lower in 13 NSCLC cell lines but was 11-fold higher in one cell line (H157) than in NL20 cells. Although ectopic miR-101 efficiently decreased the ATM and DNA-PKcs levels and increased the radiosensitization level in H1299, H1975, and A549 cells, it did not change the levels of the miR-101 targets or radiosensitivity in H157 cells. Similar results were observed in xenograft mice. Conclusions: A small number of NSCLC cell lines could have a high level of endogenous miR-101. The ectopic miR-101 was able to radiosensitize most NSCLC cells, except for the NSCLC cell lines that had a much higher endogenous miR-101 level. These results suggest that when we choose one miRNA as a therapeutic tool, the endogenous level of the miRNA in each tumor should be considered.

  9. Searching for Stopped Gluinos at CMS

    SciTech Connect (OSTI)

    Ratnikov, Fedor

    2010-02-10

    We describe plans for a search for long-lived particles which will become stopped by the CMS detector. We will look for the subsequent decay of these particles during time intervals where there are no pp collisions in CMS: during gaps between crossings in the LHC beam structure, and during inter-fill periods between the beam being dumped and re-injection. Such long living particles decays will be recorded with dedicated calorimeter triggers. For models predicting these particles, such as split-susy gluinos, the large cross-section combined with good stopping power of CMS, yields a significant number of triggerable decays. If LHC instantaneous luminosity approaches 10{sup 32} cm{sup -2}s{sup -1} in 2009-10, 5sigma significance can be established in a matter of days, since these decays occur on top of a negligible background.Due to limited size, this paper concentrates on main idea and expected results. More details are available in https://twiki.cern.ch/twiki/bin/view/CMS/PhysicsResults.

  10. C stopping power for C ions using ToF spectrometry 

    E-Print Network [OSTI]

    Nasr, Helen Jack

    1994-01-01

    A pulsed beam time-of-flight system was used in Order to measure the stopping power of carbon ions in a thin carbon film relative to energy.loss measurements of He ions in the same carbon film. Previous measurements of He stopping powers in C...

  11. Package `MiST' July 2, 2014

    E-Print Network [OSTI]

    Brent, Roger

    Package `MiST' July 2, 2014 Type Package Title Mixed effects Score Test for continuous outcomes topics documented: MiST-package 10 1 #12;2 linear.test MiST-package Mixed effects Score Test Description Test for association between

  12. miRNAs in brain development

    SciTech Connect (OSTI)

    Petri, Rebecca; Malmevik, Josephine; Fasching, Liana; Åkerblom, Malin; Jakobsson, Johan

    2014-02-01

    MicroRNAs (miRNAs) are small, non-coding RNAs that negatively regulate gene expression at the post-transcriptional level. In the brain, a large number of miRNAs are expressed and there is a growing body of evidence demonstrating that miRNAs are essential for brain development and neuronal function. Conditional knockout studies of the core components in the miRNA biogenesis pathway, such as Dicer and DGCR8, have demonstrated a crucial role for miRNAs during the development of the central nervous system. Furthermore, mice deleted for specific miRNAs and miRNA-clusters demonstrate diverse functional roles for different miRNAs during the development of different brain structures. miRNAs have been proposed to regulate cellular functions such as differentiation, proliferation and fate-determination of neural progenitors. In this review we summarise the findings from recent studies that highlight the importance of miRNAs in brain development with a focus on the mouse model. We also discuss the technical limitations of current miRNA studies that still limit our understanding of this family of non-coding RNAs and propose the use of novel and refined technologies that are needed in order to fully determine the impact of specific miRNAs in brain development. - Highlights: • miRNAs are essential for brain development and neuronal function. • KO of Dicer is embryonically lethal. • Conditional Dicer KO results in defective proliferation or increased apoptosis. • KO of individual miRNAs or miRNA families is necessary to determine function.

  13. Optimizing detector placement for isolated intersections based on minimizing average delay and number of stops 

    E-Print Network [OSTI]

    Hoppers, Kevin Paul

    2000-01-01

    of stops was examined in this research. The relationship between the placement of detectors, volume levels and headway-timing strategies was also studied. Research was conducted with computer simulation, using both software-only and a hardware...

  14. Stop-and-go kinetics in amyloid fibrillation

    E-Print Network [OSTI]

    Jesper Fonslet; Christian Beyschau Andersen; Sandeep Krishna; Simone Pigolotti; Hisashi Yagi; Yuji Goto; Daniel Otzen; Mogens H. Jensen; Jesper Ferkinghoff-Borg

    2009-10-21

    Many human diseases are associated with protein aggregation and fibrillation. We present experiments on in vitro glucagon fibrillation using total internal reflection fluorescence microscopy, providing real-time measurements of single-fibril growth. We find that amyloid fibrils grow in an intermittent fashion, with periods of growth followed by long pauses. The observed exponential distributions of stop and growth times support a Markovian model, in which fibrils shift between the two states with specific rates. Remarkably, the probability of being in the growing (stopping) state is very close to 1/4 (3/4) in all experiments, even if the rates vary considerably. This finding suggests the presence of 4 independent conformations of the fibril tip; we discuss this possibility in terms of the existing structural knowledge.

  15. Epoxy bond and stop etch fabrication method

    DOE Patents [OSTI]

    Simmons, Jerry A. (Sandia Park, NM); Weckwerth, Mark V. (Pleasanton, CA); Baca, Wes E. (Albuquerque, NM)

    2000-01-01

    A class of epoxy bond and stop etch (EBASE) microelectronic fabrication techniques is disclosed. The essence of such techniques is to grow circuit components on top of a stop etch layer grown on a first substrate. The first substrate and a host substrate are then bonded together so that the circuit components are attached to the host substrate by the bonding agent. The first substrate is then removed, e.g., by a chemical or physical etching process to which the stop etch layer is resistant. EBASE fabrication methods allow access to regions of a device structure which are usually blocked by the presence of a substrate, and are of particular utility in the fabrication of ultrafast electronic and optoelectronic devices and circuits.

  16. miR-196a targets netrin 4 and regulates cell proliferation and migration of cervical cancer cells

    SciTech Connect (OSTI)

    Zhang, Jie; Zheng, Fangxia; Yu, Gang; Yin, Yanhua; Lu, Qingyang

    2013-11-01

    Highlights: •miR-196a was overexpressed in cervical cancer tissue compared to normal tissue. •miR-196a expression elevated proliferation and migration of cervical cancer cells. •miR-196a inhibited NTN4 expression by binding 3?-UTR region of NTN4 mRNA. •NTN4 inversely correlated with miR-196a expression in cervical tissue and cell line. •NTN4 expression was low in cervical cancer tissue compared to normal tissue. -- Abstract: Recent research has uncovered tumor-suppressive and oncogenic potential of miR-196a in various tumors. However, the expression and mechanism of its function in cervical cancer remains unclear. In this study, we assess relative expression of miR-196a in cervical premalignant lesions, cervical cancer tissues, and four cancer cell lines using quantitative real-time PCR. CaSki and HeLa cells were treated with miR-196a inhibitors, mimics, or pCDNA/miR-196a to investigate the role of miR-196a in cancer cell proliferation and migration. We demonstrated that miR-196a was overexpressed in cervical intraepithelial neoplasia 2–3 and cervical cancer tissue. Moreover, its expression contributes to the proliferation and migration of cervical cancer cells, whereas inhibiting its expression led to a reduction in proliferation and migration. Five candidate targets of miR-196a chosen by computational prediction and Cervical Cancer Gene Database search were measured for their mRNA in both miR-196a-overexpressing and -depleted cancer cells. Only netrin 4 (NTN4) expression displayed an inverse association with miR-196a. Fluorescent reporter assays revealed that miR-196a inhibited NTN4 expression by targeting one binding site in the 3?-untranslated region (3?-UTR) of NTN4 mRNA. Furthermore, qPCR and Western blot assays verified NTN4 expression was downregulated in cervical cancer tissues compared to normal controls, and in vivo mRNA level of NTN4 inversely correlated with miR-196a expression. In summary, our findings provide new insights about the functional role of miR-196a in cervical carcinogenesis and suggested a potential use of miR-196a for clinical diagnosis and as a therapeutic target.

  17. LBNL -45423 Stopping Duct Quacks: Longevity of

    E-Print Network [OSTI]

    LBNL - 45423 Stopping Duct Quacks: Longevity of Residential Duct Sealants Max H. Sherman, Iain S Duct leakage has been identified as a major source of energy loss in residential buildings. Most duct leakage occurs at the connections to registers, plenums or branches in the duct system. At each

  18. The multi-stop aircraft routing problem 

    E-Print Network [OSTI]

    Garci?a Castan?eda, Salvador

    1995-01-01

    which facilitate solution. Since the constraint set of the multi-stop aircraft routing problem includes 0/1 mixed rows, we first derive valid inequalities for this type of regions. Then we apply these results to the constraint set of the routing problem...

  19. Handicap Parking Tulsa Transit Bus Stop

    E-Print Network [OSTI]

    Oklahoma, University of

    Handicap Parking N S W E Bike Rack Tulsa Transit Bus Stop Building Entrance Parking Founders Hall..........Tulsa Graduate College C Wing Floor 1..........Security Office/Police Dispatch Floor 1..........Center of Applied Research for Non-Profit Organizations Floor 1..........OU-Tulsa Enrollment & Student Financial

  20. MI high power operation and future plans

    SciTech Connect (OSTI)

    Kourbanis, Ioanis; /Fermilab

    2008-09-01

    Fermilab's Main Injector on acceleration cycles to 120 GeV has been running a mixed mode operation delivering beam to both the antiproton source for pbar production and to the NuMI[1] target for neutrino production since 2005. On January 2008 the slip stacking process used to increase the beam to the pbar target was expanded to include the beam to the NuMI target increasing both the beam intensity and power. The current high power MI operation will be described along with the near future plans.

  1. Numerical Approximations of Stochastic Optimal Stopping and Control Problems 

    E-Print Network [OSTI]

    Siska, David

    2007-01-01

    We study numerical approximations for the payoff function of the stochastic optimal stopping and control problem. It is known that the payoff function of the optimal stopping and control problem corresponds to the solution ...

  2. Which is Greener: Idle, or Stop and Restart? | Department of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    is Greener: Idle, or Stop and Restart? This poster presents data comparing fuel use and emissions for short passenger-car stops vs. idling. Fuel use is always greater for idling...

  3. Energy Savers: Your One Stop Shop for Energy Efficiency Upgrades...

    Office of Environmental Management (EM)

    Your One Stop Shop for Energy Efficiency Upgrades Energy Savers: Your One Stop Shop for Energy Efficiency Upgrades This is a presentation from Energy Impact Illinois posted on the...

  4. The NuMI Neutrino Beam

    E-Print Network [OSTI]

    P. Adamson; K. Anderson; M. Andrews; R. Andrews; I. Anghel; D. Augustine; A. Aurisano; S. Avvakumov; D. S. Ayres; B. Baller; B. Barish; G. Barr; W. L. Barrett; R. H. Bernstein; J. Biggs; M. Bishai; A. Blake; V. Bocean; G. J. Bock; D. J. Boehnlein; D. Bogert; K. Bourkland; S. V. Cao; C. M. Castromonte; S. Childress; B. C. Choudhary; J. A. B. Coelho; J. H. Cobb; L. Corwin; D. Crane; J. P. Cravens; D. Cronin-Hennessy; R. J. Ducar; J. K. de Jong; A. V. Devan; N. E. Devenish; M. V. Diwan; A. R. Erwin; C. O. Escobar; J. J. Evans; E. Falk; G. J. Feldman; T. H. Fields; R. Ford; M. V. Frohne; H. R. Gallagher; V. Garkusha; R. A. Gomes; M. C. Goodman; P. Gouffon; N. Graf; R. Gran; N. Grossman; K. Grzelak; A. Habig; S. R. Hahn; D. Harding; D. Harris; P. G. Harris; J. Hartnell; R. Hatcher; S. Hays; K. Heller; A. Holin; J. Huang; J. Hylen; A. Ibrahim; D. Indurthy; G. M. Irwin; Z. Isvan; D. E. Jaffe; C. James; D. Jensen; J. Johnstone; T. Kafka; S. M. S. Kasahara; G. Koizumi; S. Kopp; M. Kordosky; A. Kreymer; K. Lang; C. Laughton; G. Lefeuvre; J. Ling; P. J. Litchfield; L. Loiacono; P. Lucas; W. A. Mann; A. Marchionni; M. L. Marshak; N. Mayer; C. McGivern; M. M. Medeiros; R. Mehdiyev; J. R. Meier; M. D. Messier; D. G. Michael; R. H. Milburn; J. L. Miller; W. H. Miller; S. R. Mishra; S. Moed Sher; C. D. Moore; J. Morfin; L. Mualem; S. Mufson; S. Murgia; M. Murtagh; J. Musser; D. Naples; J. K. Nelson; H. B. Newman; R. J. Nichol; J. A. Nowak; J. O Connor; W. P. Oliver; M. Olsen; M. Orchanian; S. Osprey; R. B. Pahlka; J. Paley; A. Para; R. B. Patterson; T. Patzak; Z. Pavlovic; G. Pawloski; A. Perch; E. A. Peterson; D. A. Petyt; M. M. Pfutzner; S. Phan-Budd; R. K. Plunkett; N. Poonthottathil; P. Prieto; D. Pushka; X. Qiu; A. Radovic; R. A. Rameika; J. Ratchford; B. Rebel; R. Reilly; C. Rosenfeld; H. A. Rubin; K. Ruddick; M. C. Sanchez; N. Saoulidou; L. Sauer; J. Schneps; D. Schoo; A. Schreckenberger; P. Schreiner; P. Shanahan; R. Sharma; W. Smart; C. Smith; A. Sousa; A. Stefanik; N. Tagg; R. L. Talaga; G. Tassotto; J. Thomas; J. Thompson; M. A. Thomson; X. Tian; A. Timmons; D. Tinsley; S. C. Tognini; R. Toner; D. Torretta; I. Trostin; G. Tzanakos; J. Urheim; P. Vahle; K. Vaziri; E. Villegas; B. Viren; G. Vogel; R. C. Webber; A. Weber; R. C. Webb; A. Wehmann; C. White; L. Whitehead; L. H. Whitehead; S. G. Wojcicki; M. L. Wong-Squires; T. Yang; F. X. Yumiceva; V. Zarucheisky; R. Zwaska

    2015-07-29

    This paper describes the hardware and operations of the Neutrinos at the Main Injector (NuMI) beam at Fermilab. It elaborates on the design considerations for the beam as a whole and for individual elements. The most important design details of individual components are described. Beam monitoring systems and procedures, including the tuning and alignment of the beam and NuMI long-term performance, are also discussed.

  5. The NuMI Neutrino Beam

    E-Print Network [OSTI]

    Adamson, P; Andrews, M; Andrews, R; Anghel, I; Augustine, D; Aurisano, A; Avvakumov, S; Ayres, D S; Baller, B; Barish, B; Barr, G; Barrett, W L; Bernstein, R H; Biggs, J; Bishai, M; Blake, A; Bocean, V; Bock, G J; Boehnlein, D J; Bogert, D; Bourkland, K; Cao, S V; Castromonte, C M; Childress, S; Choudhary, B C; Coelho, J A B; Cobb, J H; Corwin, L; Crane, D; Cravens, J P; Cronin-Hennessy, D; Ducar, R J; de Jong, J K; Devan, A V; Devenish, N E; Diwan, M V; Erwin, A R; Escobar, C O; Evans, J J; Falk, E; Feldman, G J; Fields, T H; Ford, R; Frohne, M V; Gallagher, H R; Garkusha, V; Gomes, R A; Goodman, M C; Gouffon, P; Graf, N; Gran, R; Grossman, N; Grzelak, K; Habig, A; Hahn, S R; Harding, D; Harris, D; Harris, P G; Hartnell, J; Hatcher, R; Hays, S; Heller, K; Holin, A; Huang, J; Hylen, J; Ibrahim, A; Indurthy, D; Irwin, G M; Isvan, Z; Jaffe, D E; James, C; Jensen, D; Johnstone, J; Kafka, T; Kasahara, S M S; Koizumi, G; Kopp, S; Kordosky, M; Kreymer, A; Lang, K; Laughton, C; Lefeuvre, G; Ling, J; Litchfield, P J; Loiacono, L; Lucas, P; Mann, W A; Marchionni, A; Marshak, M L; Mayer, N; McGivern, C; Medeiros, M M; Mehdiyev, R; Meier, J R; Messier, M D; Michael, D G; Milburn, R H; Miller, J L; Miller, W H; Mishra, S R; Sher, S Moed; Moore, C D; Morfin, J; Mualem, L; Mufson, S; Murgia, S; Murtagh, M; Musser, J; Naples, D; Nelson, J K; Newman, H B; Nichol, R J; Nowak, J A; Connor, J O; Oliver, W P; Olsen, M; Orchanian, M; Osprey, S; Pahlka, R B; Paley, J; Para, A; Patterson, R B; Patzak, T; Pavlovic, Z; Pawloski, G; Perch, A; Peterson, E A; Petyt, D A; Pfutzner, M; Phan-Budd, S; Plunkett, R K; Poonthottathil, N; Prieto, P; Pushka, D; Qiu, X; Radovic, A; Rameika, R A; Ratchford, J; Rebel, B; Reilly, R; Rosenfeld, C; Rubin, H A; Ruddick, K; Sanchez, M C; Saoulidou, N; Sauer, L; Schneps, J; Schoo, D; Schreckenberger, A; Schreiner, P; Shanahan, P; Sharma, R; Smart, W; Smith, C; Sousa, A; Stefanik, A; Tagg, N; Talaga, R L; Tassotto, G; Thomas, J; Thompson, J; Thomson, M A; Tian, X; Timmons, A; Tinsley, D; Tognini, S C; Toner, R; Torretta, D; Trostin, I; Tzanakos, G; Urheim, J; Vahle, P; Vaziri, K; Villegas, E; Viren, B; Vogel, G; Webber, R C; Weber, A; Webb, R C; Wehmann, A; White, C; Whitehead, L; Whitehead, L H; Wojcicki, S G; Wong-Squires, M L; Yang, T; Yumiceva, F X; Zarucheisky, V; Zwaska, R

    2015-01-01

    This paper describes the hardware and operations of the Neutrinos at the Main Injector (NuMI) beam at Fermilab. It elaborates on the design considerations for the beam as a whole and for individual elements. The most important design details of individual components are described. Beam monitoring systems and procedures, including the tuning and alignment of the beam and NuMI long-term performance, are also discussed.

  6. The NuMI Neutrino Beam

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Adamson, P.; Anderson, K.; Andrews, M.; Andrews, R.; Anghel, I.; Augustine, D.; Aurisano, A.; Avvakumov, S.; Ayres, D. S.; Baller, B.; et al

    2015-10-20

    Our paper describes the hardware and operations of the Neutrinos at the Main Injector (NuMI) beam at Fermilab. It elaborates on the design considerations for the beam as a whole and for individual elements. The most important part of our design details pertaining to individual components is described. Beam monitoring systems and procedures, including the tuning and alignment of the beam and NuMI long-term performance, are also discussed.

  7. Stopped Decision Processes in conjunction with General Utility

    E-Print Network [OSTI]

    Yasuda, Masami

    Stopped Decision Processes in conjunction with General Utility Yoshinobu KADOTA Dep. of Math process and the stopping prob­ lem, called Stopped Decision Processes, with a general utility and piecewise deterministic Markov processes, etc. Our aim is to formulate the general utility

  8. STOP WORK POLICY for Hanford Site Contractors

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust, High-Throughput Analysis of Protein1-0845*RV6STAT 12293GGObjective  SearchSTOP WORK

  9. Where's My Bus Stop? Supporting Independence of Blind Transit Riders with StopInfo

    E-Print Network [OSTI]

    Manchak, John

    in the Seattle area with information entered by the community, primarily as they waited at these stops and Society]: Social Is sues--Assistive technologies for persons with disabilities General Terms Design]. They often search for physical landmarks such as the bus shelter, benches, or transit sign as a cue

  10. Stopping supersonic oxygen with a series of pulsed electromagnetic coils: A molecular coilgun Edvardas Narevicius,1

    E-Print Network [OSTI]

    Texas at Austin. University of

    Stopping supersonic oxygen with a series of pulsed electromagnetic coils: A molecular coilgun, using a series of pulsed electromagnetic coils. A series of coils is fired in a timed sequence to bring in some experiments by interactions with pulsed electric fields Stark decelerator 4­6 , by inter- actions

  11. Report on the first VLHC photon stop cryogenic design experiment

    SciTech Connect (OSTI)

    Michael Geynisman et al.

    2003-09-15

    As part of Fermilab's study of a Very Large Hadron Collider, a water-cooled photon stop was proposed as a device to intercept the synchrotron radiation emitted by the high-energy proton beams in the high field superconducting magnets with minimal plug-cooling power. Photon stops are radiation absorbers operating at room temperature that protrude into the beam tube at the end of each bending magnet to scrape the synchrotron light emitted by the beam one magnet up-stream. Among the technological challenges regarding photon stops is their cryo-design. The photon stop is water-cooled and operates in a cryogenic environment. A careful cryo-design is therefore essential to enable operation at minimum heat transfer between the room temperature sections and the cryogenic parts. A photon stop cryo-design was developed and a prototype was built. This paper presents the results of the cryogenic experiments conducted on the first VLHC photon stop prototype.

  12. Sequence determinants of pri-miRNA processing

    E-Print Network [OSTI]

    Auyeung, Vincent C. (Vincent Churk-man)

    2012-01-01

    MicroRNAs (miRNAs) are short RNAs that regulate many processes in physiology and pathology by guiding the repression of target messenger RNAs. For classification purposes, miRNAs are defined as ~22 nt RNAs that are produced ...

  13. miR-132 and miR-212 are increased in pancreatic cancer and target the retinoblastoma tumor suppressor

    SciTech Connect (OSTI)

    Park, Jong-Kook [College of Pharmacy, Ohio State University, Columbus, OH 43210 (United States)] [College of Pharmacy, Ohio State University, Columbus, OH 43210 (United States); Henry, Jon C. [Department of Surgery, Ohio State University, Columbus, OH 43210 (United States)] [Department of Surgery, Ohio State University, Columbus, OH 43210 (United States); Jiang, Jinmai [College of Pharmacy, Ohio State University, Columbus, OH 43210 (United States)] [College of Pharmacy, Ohio State University, Columbus, OH 43210 (United States); Esau, Christine [Regulus Therapeutics, Carlsbad, CA (United States)] [Regulus Therapeutics, Carlsbad, CA (United States); Gusev, Yuriy [Lombardi Cancer Center, Georgetown University, Washington, DC (United States)] [Lombardi Cancer Center, Georgetown University, Washington, DC (United States); Lerner, Megan R. [Veterans Affairs Medical Center, Oklahoma City, OK (United States)] [Veterans Affairs Medical Center, Oklahoma City, OK (United States); Postier, Russell G. [Department of Surgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK (United States)] [Department of Surgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK (United States); Brackett, Daniel J. [Veterans Affairs Medical Center, Oklahoma City, OK (United States)] [Veterans Affairs Medical Center, Oklahoma City, OK (United States); Schmittgen, Thomas D., E-mail: Schmittgen.2@osu.edu [College of Pharmacy, Ohio State University, Columbus, OH 43210 (United States)

    2011-03-25

    Research highlights: {yields} The expression of miR-132 and miR-212 are significantly increased in pancreatic cancer. {yields} miR-132 and miR-212 target the tumor suppressor pRb, resulting in enhanced proliferation. {yields} miR-132 and miR-212 expression is increased by a {beta}2 adrenergic receptor agonist, suggesting a novel mechanism for pancreatic cancer progression. -- Abstract: Numerous microRNAs (miRNAs) are reported as differentially expressed in cancer, however the consequence of miRNA deregulation in cancer is unknown for many miRNAs. We report that two miRNAs located on chromosome 17p13, miR-132 and miR-212, are over-expressed in pancreatic adenocarcinoma (PDAC) tissues. Both miRNAs are predicted to target the retinoblastoma tumor suppressor, Rb1. Validation of this interaction was confirmed by luciferase reporter assay and western blot in a pancreatic cancer cell line transfected with pre-miR-212 and pre-miR-132 oligos. Cell proliferation was enhanced in Panc-1 cells transfected with pre-miR-132/-212 oligos. Conversely, antisense oligos to miR-132/-212 reduced cell proliferation and caused a G{sub 2}/M cell cycle arrest. The mRNA of a number of E2F transcriptional targets were increased in cells over expressing miR-132/-212. Exposing Panc-1 cells to the {beta}2 adrenergic receptor agonist, terbutaline, increased the miR-132 and miR-212 expression by 2- to 4-fold. We report that over-expression of miR-132 and miR-212 result in reduced pRb protein in pancreatic cancer cells and that the increase in cell proliferation from over-expression of these miRNAs is likely due to increased expression of several E2F target genes. The {beta}2 adrenergic pathway may play an important role in this novel mechanism.

  14. Stopping single photons in one-dimensional circuit quantum electrodynamics systems Jung-Tsung Shen, M. L. Povinelli, Sunil Sandhu, and Shanhui Fan*

    E-Print Network [OSTI]

    Fan, Shanhui

    Stopping single photons in one-dimensional circuit quantum electrodynamics systems Jung-Tsung Shen January 2007 We propose a mechanism to stop and time reverse single photons in one-dimensional circuit of the superconducting charge quantum bit charge qubit to predict one-photon transport properties in multiple

  15. “Nodal Gap” Induced by the Incommensurate Diagonal Spin Density Modulation in Underdoped High- <mi>Tmi>c> Superconductors

    SciTech Connect (OSTI)

    Zhou, Tao [Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China; Gao, Yi [Nanjing Normal University, Nanjing 210023, China; Zhu, Jian-Xin [Los Alamos National Laboratory, Los Alamos, NM 87545, USA

    2015-01-01

    Recently it was revealed that the whole Fermi surface is fully gapped for several families of underdoped cuprates. The existence of the finite energy gap along the<mi>d>-wave nodal lines (nodal gap) contrasts the common understanding of the<mi>d>-wave pairing symmetry, which challenges the present theories for the high-<mi>Tmi><mi>c>superconductors. Here we propose that the incommensurate diagonal spin-density-wave order can account for the above experimental observation. The Fermi surface and the local density of states are also studied. Our results are in good agreement with many important experiments in high-<mi>Tmi><mi>c>superconductors.

  16. 11/3/08 2:43 PMTale of the Tapeworm (Squeamish Readers Stop Here) -New York Times Page 1 of 2http://www.nytimes.com/2006/08/08/health/08case.html?_r=1&pagewanted=print&oref=slogin

    E-Print Network [OSTI]

    Davis, Richard E.

    of the Tapeworm (Squeamish Readers Stop Here) By LARRY ZAROFF, M.D. This is a Jewish fish story. Or more comes through. It's a safe technique with latkes or kreplach but not always with gefilte fish, a ground concoction of freshwater fish, spices, eggs, salt and matzo meal. My mother never became sick from tasting

  17. Algorithm-Based Fault Tolerance for Fail-Stop Failures

    E-Print Network [OSTI]

    Dongarra, Jack

    after failures, the next generation high performance computing applications need to be able to continue1 Algorithm-Based Fault Tolerance for Fail-Stop Failures Zizhong Chen and Jack Dongarra Abstract Fail-stop failures in distributed environments are often tolerated by checkpointing or message logging

  18. FINITE-FUEL SINGULAR CONTROL WITH DISCRETIONARY STOPPING

    E-Print Network [OSTI]

    Wang, Hui

    FINITE-FUEL SINGULAR CONTROL WITH DISCRETIONARY STOPPING IOANNIS KARATZAS DepartmentsG40; Secondary 60J65. Key Words: Singular stochastic control, optimal stopping, finite-fuel We discuss the finite-fuel, singular stochastic control problem of optimally tracking the standard

  19. What can you do to stop the flu? Cover your cough! Help stop the spread of germs by

    E-Print Network [OSTI]

    Burke, Peter

    What can you do to stop the flu? · Cover your cough! Help stop the spread of germs by covering your mouth and nose when you cough or sneeze with a tissue or with your upper sleeve. · Wash your hands surfaces. · Flu symptoms include: - Fever - Extreme tiredness - Headache - Cough - Muscle aches - Runny

  20. The Borneo Project : Indonesia Fails to Stop Illegal Logging, Report Says Indonesia Fails to Stop Illegal Logging, Report Says

    E-Print Network [OSTI]

    The Borneo Project : Indonesia Fails to Stop Illegal Logging, Report Says Indonesia Fails to Stop Illegal Logging, Report Says by Irwan Firdaus, The Associated Press January 15th, 2003 JAKARTA, Indonesia -- Corruption in Indonesia's police and military has contributed to a surge in illegal logging that has

  1. Liver fibrosis causes downregulation of miRNA-150 and miRNA-194 in hepatic stellate cells, and their overexpression causes decreased stellate cell activation.

    E-Print Network [OSTI]

    Wu, Jian; Zern, M A

    2010-01-01

    Liver ?brosis causes downregulation of miRNA-150 and miRNA-and their overexpression causes decreased stellate cellJ, Zern MA. Liver ?brosis causes downregulation of miRNA-150

  2. Stop Fee Pick-up Place Bus Leaves By Stop 1 $40 Astoria Clatsop County Extension, 2001 Marine Drive 9:15 AM

    E-Print Network [OSTI]

    Tullos, Desiree

    9:15 AM Stop 2 $30 Hillsboro Winco Foods, 1500 SW Oak St 11:15 AM Stop 3 $20 McMinnville Walmart Stop 2 McMinnville Walmart, 2375 NE Highway 99w 12:30 PM Stop 3 Hillsboro Winco Foods, 1500 SW Oak St 2

  3. Stop Fee Pick-up Place Bus Leaves By Stop 1 $50 Lakeview OSU Extension Office, 103 South "E" St 7:00 AM

    E-Print Network [OSTI]

    Tullos, Desiree

    :00 AM Stop 2 $40 Paisley Paisley Community Hall, 260 Green St 8:00 AM Stop 3 $40 Silver Lake Café Stop 4 Silver Lake Café Parking Lot, 5320 Hwy 31 5:00 PM Stop 5 Paisley Paisley Community Hall, 260

  4. Analytical Study of Hexapod miRNAs using Phylogenetic Methods

    E-Print Network [OSTI]

    Mishra, A K

    2012-01-01

    MicroRNAs (miRNAs) are a class of non-coding RNAs that regulate gene expression. Identification of total number of miRNAs even in completely sequenced organisms is still an open problem. However, researchers have been using techniques that can predict limited number of miRNA in an organism. In this paper, we have used homology based approach for comparative analysis of miRNA of hexapoda group .We have used Apis mellifera, Bombyx mori, Anopholes gambiae and Drosophila melanogaster miRNA datasets from miRBase repository. We have done pair wise as well as multiple alignments for the available miRNAs in the repository to identify and analyse conserved regions among related species. Unfortunately, to the best of our knowledge, miRNA related literature does not provide in depth analysis of hexapods. We have made an attempt to derive the commonality among the miRNAs and to identify the conserved regions which are still not available in miRNA repositories. The results are good approximation with a small number of mis...

  5. Spot the stop with a b-tag

    E-Print Network [OSTI]

    Ferretti, Gabriele; Petersson, Christoffer; Torre, Riccardo

    2015-01-01

    The LHC searches for light compressed stop squarks have resulted in considerable bounds in the case where the stop decays to a neutralino and a charm quark. However, in the case where the stop decays to a neutralino, a bottom quark and two fermions via an off-shell W-boson, there is currently a significant unconstrained region in the stop-neutralino mass plane, still allowing for stop masses in the range 90-140 GeV. In this paper we propose a new monojet-like search for light stops, optimized for the four-body decay mode, in which at least one b-tagged jet is required. We show that, already by using the existing 8 TeV LHC data set, such a search would cover the entire unconstrained region. Moreover, in the process of validating our tools against an ATLAS monojet search, we show that the existing limit can be extended to exclude also stop masses below 100 GeV.

  6. Effect of isospin dependent cross-section on nuclear stopping

    E-Print Network [OSTI]

    Anupriya Jain; Suneel Kumar

    2011-07-29

    Nuclear stopping in heavy ion collisions (HIC) has been studied by means of rapidity distribution and asymmetry of nucleon momentum distribution. It is an important quantity in determining the outcome of a reaction. Fen Fu {\\it et al.,} \\cite{2} calculate both the radial flow and the degree of nuclear stopping in Pb + Pb and Ni + Ni at 0.4, 0.8 and 1.2 GeV/neucleon. They found that the expansion velocity as well as the degree of nuclear stopping are higher in the heavier system at all energies.

  7. Evidence of efficient stop codon readthrough in four mammalian genes

    E-Print Network [OSTI]

    Loughran, Gary

    Stop codon readthrough is used extensively by viruses to expand their gene expression. Until recent discoveries in Drosophila, only a very limited number of readthrough cases in chromosomal genes had been reported. Analysis ...

  8. Acoustical study of the development of stop consonants in children

    E-Print Network [OSTI]

    Imbrie, Annika Karin Karlsson

    2005-01-01

    This study focuses on the acoustic patterns of stop consonants and adjacent vowels as they develop in young children (ages 2;6-3;3) over a six month period. Speech is generated using a series of articulatory, laryngeal, ...

  9. Power Outage 1.Stop serving food and beverages.

    E-Print Network [OSTI]

    LESSON1 Power Outage 1.Stop serving food and beverages. Notify customers. 2.Do two things food. Emergency Readiness for Food Workers #12;LESSON1 Power Outage 5.Food being held cold: Discard

  10. Activity of group-transported horses during onboard rest stops 

    E-Print Network [OSTI]

    Keen, Heidi A.

    2007-04-25

    Activity of group-transported horses was evaluated during onboard rest stops to determine if horses derive meaningful rest. A single-deck semi-trailer separated into three compartments was used for all shipments. In ...

  11. Nanomachines: How Viruses Work, and How We Can Stop Them

    ScienceCinema (OSTI)

    Carolyn Bertozzi

    2010-01-08

    Nature's Nasty Nanomachines: How Viruses Work, and How We Can Stop Them. Carolyn Bertozzi, director of Berkeley Lab's Molecular Foundry, discusses this topic at a Feb. 21, 2009 Nano*High talk.

  12. BMPs Regulate the Oft Development via miRNAs 

    E-Print Network [OSTI]

    Bai, Yan

    2014-08-04

    c-Jun N-terminal Kinase LAP Latency Associated Peptide LLC Large Latent Complex LTBP Latent Tgf-? Binding Protein MFS Marfan Syndrome mi...

  13. ,"Detroit, MI Natural Gas Pipeline Imports From Canada (MMcf...

    U.S. Energy Information Administration (EIA) Indexed Site

    ,"Worksheet Name","Description"," Of Series","Frequency","Latest Data for" ,"Data 1","Detroit, MI Natural Gas Pipeline Imports From Canada (MMcf)",1,"Annual",2014 ,"Release...

  14. Licensing stop place before laterals : a study of acoustic cues relevant to the perception of stop-lateral sequences

    E-Print Network [OSTI]

    Michaels, Jennifer M. (Jennifer Marie)

    2011-01-01

    In phonological analyses of both adult and child language, a *dl constraint has frequently been used as a shorthand to indicate that coronal stops are dispreferred before laterals (Dinnsen et al. 2001). This dispreference ...

  15. miR-206 is down-regulated in breast cancer and inhibits cell proliferation through the up-regulation of cyclinD2

    SciTech Connect (OSTI)

    Zhou, Jing; Tian, Ye; Li, Juan; Lu, Binbin; Sun, Ming; Zou, Yanfen; Kong, Rong; Luo, Yanhong; Shi, Yongguo; Wang, Keming; Ji, Guozhong

    2013-04-05

    Highlights: ? miR-206 was downexpressed in tumor samples compared with matched normal samples. ? Enhanced expression of miR-206 could inhibit breast cancer growth in vitro. ? Luciferase confirmed miR-206 functions as an anti-oncogene by targeting cyclinD2. ? A reverse correlation between miR-206 and cyclinD2 in breast cancer was found. -- Abstract: MicroRNAs act as important gene regulators in human genomes, and their aberrant expression is linked to many malignancies. Aberrant expression of miR-206 has been frequently reported in cancer studies; however, the role and mechanism of its function in breast cancer remains unclear. Quantitative real-time PCR was performed to detect the relative expression levels of miR-206 in breast cancer and normal breast tissues. Lower expression of miR-206 in breast cancer tissues was associated with larger tumour size and a more advanced clinical stage. Further in vitro observations showed that the enforced expression of miR-206 in MCF-7 breast cancer cells inhibited cell growth by blocking the G1/S transition and suppressed cell proliferation and colony formation, implying that miR-206 functions as a tumour suppressor in the progression of breast cancer. Interestingly, Luciferase assays first revealed that miR-206 inhibited cyclinD2 expression by targeting two binding sites in the 3?-untranslated region of cyclinD2 mRNA. qRT-PCR and Western blot assays verified that miR-206 reduced cyclinD2 expression at both the mRNA and protein levels. A reverse correlation between miR-206 and cyclinD2 expression was noted in breast cancer tissues. Altogether, our results identify a crucial tumour suppressive role of miR-206 in the progression of breast cancer, at least partly via up-regulation of the expression of cyclinD2, and suggest that miR-206 might be a candidate prognostic predictor or an anticancer therapeutic target for breast cancer patients.

  16. Top Polarization in Stop Production at the LHC

    E-Print Network [OSTI]

    G. Belanger; R. M. Godbole; L. Hartgring; I. Niessen

    2012-12-14

    We survey the expected polarization of the top produced in the decay of a scalar top quark, $\\tilde t \\rightarrow {\\tilde t}\\chi_i^0, i =1-2$. The phenomenology is quite interesting, since the expected polarization depends both on the mixing in the stop and neutralino sectors and on the mass differences between the stop and the neutralino. We find that a mixed stop behaves almost like a right-handed stop due to the larger hypercharge that enters the stop/top/gaugino coupling and that these polarisation effects disappear, when $m_{\\tilde t_1} \\approx m_t+m_{\\tilde\\chi^0_i}$. After a discussion on the expected top polarization from the decay of a scalar top quark, we focus on the interplay of polarization and kinematics at the LHC. We discuss different probes of the top polarization in terms of lab-frame observables. We find that these observables faithfully reflect the polarization of the parent top-quark, but also have a non-trivial dependence on the kinematics of the stop production and decay process. In addition, we illustrate the effect of top polarization on the energy and transverse momentum of the decay lepton in the laboratory frame. Our results show that both spectra are softened substantially in case of a negatively polarized top, particularly for a large mass difference between the stop and the neutralino. Thus, the search strategies, and the conclusions that can be drawn from them, depends not just on the mass difference $m_{\\tilde t} - m_{\\tilde\\chi_{i}^{0}}$ due to the usual kinematic effects but also on the effects of top polarization on the decay kinematics the extent of which depends in turn on the said mass difference.

  17. Members of the miRNA-200 Family Regulate Olfactory Neurogenesis

    E-Print Network [OSTI]

    Choi, Philip S.

    MicroRNAs (miRNAs) are highly expressed in vertebrate neural tissues, but the contribution of specific miRNAs to the development and function of different neuronal populations is still largely unknown. We report that miRNAs ...

  18. Method and apparatus to debug an integrated circuit chip via synchronous clock stop and scan

    DOE Patents [OSTI]

    Bellofatto, Ralph E. (Ridgefield, CT); Ellavsky, Matthew R. (Rochester, MN); Gara, Alan G. (Mount Kisco, NY); Giampapa, Mark E. (Irvington, NY); Gooding, Thomas M. (Rochester, MN); Haring, Rudolf A. (Cortlandt Manor, NY); Hehenberger, Lance G. (Leander, TX); Ohmacht, Martin (Yorktown Heights, NY)

    2012-03-20

    An apparatus and method for evaluating a state of an electronic or integrated circuit (IC), each IC including one or more processor elements for controlling operations of IC sub-units, and each the IC supporting multiple frequency clock domains. The method comprises: generating a synchronized set of enable signals in correspondence with one or more IC sub-units for starting operation of one or more IC sub-units according to a determined timing configuration; counting, in response to one signal of the synchronized set of enable signals, a number of main processor IC clock cycles; and, upon attaining a desired clock cycle number, generating a stop signal for each unique frequency clock domain to synchronously stop a functional clock for each respective frequency clock domain; and, upon synchronously stopping all on-chip functional clocks on all frequency clock domains in a deterministic fashion, scanning out data values at a desired IC chip state. The apparatus and methodology enables construction of a cycle-by-cycle view of any part of the state of a running IC chip, using a combination of on-chip circuitry and software.

  19. miR-92a family and their target genes in tumorigenesis and metastasis

    SciTech Connect (OSTI)

    Li, Molin; Guan, Xingfang; Sun, Yuqiang; Mi, Jun; Shu, Xiaohong; Liu, Fang; Li, Chuangang

    2014-04-15

    The miR-92a family, including miR-25, miR-92a-1, miR-92a-2 and miR-363, arises from three different paralog clusters miR-17-92, miR-106a-363, and miR-106b-25 that are highly conservative in the process of evolution, and it was thought as a group of microRNAs (miRNAs) correlated with endothelial cells. Aberrant expression of miR-92a family was detected in multiple cancers, and the disturbance of miR-92a family was related with tumorigenesis and tumor development. In this review, the progress on the relationship between miR-92a family and their target genes and malignant tumors will be summarized. - Highlights: • Aberrant expression of miR-92a, miR-25 and miR-363 can be observed in many kinds of malignant tumors. • The expression of miR-92a family is regulated by LOH, epigenetic alteration, transcriptional factors such as SP1, MYC, E2F, wild-type p53 etc. • Roles of miR-92a family in tumorigenesis and development: promoting cell proliferation, invasion and metastasis, inhibiting cell apoptosis.

  20. Stop and frisk: What's the problem? Andrew Gelman

    E-Print Network [OSTI]

    Gelman, Andrew

    a criminal record, compared to a white man, then in settings with little or ambiguous information it would, and Hispanics in New York City. Police records revealed that ethnic minorities were being stopped at a much Race and Citizenship, by Charles R. Epp, Steven Maynard- Moody, and Donald Haider-Harkel, for Criminal

  1. The Economics of Optimal Stopping Graham A. Davis

    E-Print Network [OSTI]

    mine in northern Alberta in anticipation of lower future capital and operating costs.1 The mathematics delay is the sum of a capital gain on the project value and a capital loss on the option premium associated with waiting. The opportunity cost of delay is the short rate of interest. Prior to stopping

  2. Fatigue Enhancement of Undersized, Drilled Crack-Stop Holes

    E-Print Network [OSTI]

    Crain, Joshua Sakumura

    2010-04-20

    A common technique used to prevent the propagation of cracks in bridge girders is drilling crack-stop holes at the crack tips. By doing so, stress concentrations at the tip of the cracks are reduced and fatigue life of the ...

  3. Absence of anomalous stopping in heavy ion collisions

    E-Print Network [OSTI]

    A. Capella

    2002-05-21

    We show that the baryon stopping observed in heavy ion collisions both at CERN-SPS and at RHIC can be derived from the one observed in proton-proton collisions. No increase in the size of the baryon junction component is required between small size $(pp)$ and large size (AA) systems.

  4. miR-143 Interferes with ERK5 Signaling, and Abrogates Prostate Cancer Progression in Mice

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    miR-143 Interferes with ERK5 Signaling, and Abrogates Prostate Cancer Progression in Mice Cyrielle-regulated kinase-5 (ERK5) activity. We show here that ERK5 is a miR-143 target in prostate cancer. Conclusions: mi, Apparailly F, Fernandez PL, et al. (2009) miR-143 Interferes with ERK5 Signaling, and Abrogates Prostate

  5. NuMI Target Station AHIPA09 10/19/09

    E-Print Network [OSTI]

    McDonald, Kirk

    MI Target Station AHIPA09 10/19/09 Jim Hylen/FNAL Page 11Remote 5-axis lift table Numi target+baffle on liftNuMI Target Station AHIPA09 10/19/09 Jim Hylen/FNAL Page 1 Target Station Infrastructure: The Nu slide overview of NuMI #12;NuMI Target Station AHIPA09 10/19/09 Jim Hylen/FNAL Page 2 NuMI produces

  6. Regulation of Synaptic Structure and Function by FMRP-Associated MicroRNAs miR-125b and miR-132

    E-Print Network [OSTI]

    Edbauer, Dieter

    MicroRNAs (miRNAs) are noncoding RNAs that suppress translation of specific mRNAs. The miRNA machinery interacts with fragile X mental retardation protein (FMRP), which functions as translational repressor. We show that ...

  7. Simulations of neutron multiplicity measurements with MCNP-PoliMi.

    SciTech Connect (OSTI)

    Mattingly, John K.; Pozzi, Sara A. (University of Michigan); Clarke, Shaun D. (University of Michigan); Dennis, Ben D. (University of Michigan); Miller, Eric C.

    2010-09-01

    The heightened focus on nuclear safeguards and accountability has increased the need to develop and verify simulation tools for modeling these applications. The ability to accurately simulate safeguards techniques, such as neutron multiplicity counting, aids in the design and development of future systems. This work focuses on validating the ability of the Monte Carlo code MCNPX-PoliMi to reproduce measured neutron multiplicity results for a highly multiplicative sample. The benchmark experiment for this validation consists of a 4.5-kg sphere of plutonium metal that was moderated by various thicknesses of polyethylene. The detector system was the nPod, which contains a bank of 15 3He detectors. Simulations of the experiments were compared to the actual measurements and several sources of potential bias in the simulation were evaluated. The analysis included the effects of detector dead time, source-detector distance, density, and adjustments made to the value of {nu}-bar in the data libraries. Based on this analysis it was observed that a 1.14% decrease in the evaluated value of {nu}-bar for 239Pu in the ENDF-VII library substantially improved the accuracy of the simulation.

  8. Solar Flare Measurements with STIX and MiSolFA

    E-Print Network [OSTI]

    Casadei, Diego

    2014-01-01

    Solar flares are the most powerful events in the solar system and the brightest sources of X-rays, often associated with emission of particles reaching the Earth and causing geomagnetic storms, giving problems to communication, airplanes and even black-outs. X-rays emitted by accelerated electrons are the most direct probe of solar flare phenomena. The Micro Solar-Flare Apparatus (MiSolFA) is a proposed compact X-ray detector which will address the two biggest issues in solar flare modeling. Dynamic range limitations prevent simultaneous spectroscopy with a single instrument of all X-ray emitting regions of a flare. In addition, most X-ray observations so far are inconsistent with the high anisotropy predicted by the models usually adopted for solar flares. Operated at the same time as the STIX instrument of the ESA Solar Orbiter mission, at the next solar maximum (2020), they will have the unique opportunity to look at the same flare from two different directions: Solar Orbiter gets very close to the Sun wit...

  9. Detecting, tracking, and warning of traffic threats to police stopped along the roadside

    E-Print Network [OSTI]

    Karraker, James (James D.)

    2013-01-01

    Despite years of research into improving the safety of police roadside stops, reckless drivers continue to injure or kill police personnel stopped on the roadside at an alarming rate. We have proposed to reduce this problem ...

  10. Reaction-in-Flight Neutrons and the Stopping Power in Cryogenic...

    Office of Scientific and Technical Information (OSTI)

    Reaction-in-Flight Neutrons and the Stopping Power in Cryogenic NIF Capsules Citation Details In-Document Search Title: Reaction-in-Flight Neutrons and the Stopping Power in...

  11. Fact #853 December 29, 2014 Stop/Start Technology is in nearly...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    3 December 29, 2014 StopStart Technology is in nearly 5% of All New Light Vehicles Produced Fact 853 December 29, 2014 StopStart Technology is in nearly 5% of All New Light...

  12. Energy Savers: A one-stop energy efficiency shop for multifamily...

    Energy Savers [EERE]

    A one-stop energy efficiency shop for multifamily building owners Energy Savers: A one-stop energy efficiency shop for multifamily building owners This is a document from Energy...

  13. Optimizing a start-stop system to minimize fuel consumption using machine learning

    E-Print Network [OSTI]

    Hollingsworth, Noel

    2014-01-01

    Many people are working on improving the efficiency of car's engines. One approach to maximizing efficiency has been to create start-stop systems. These systems shut the car's engine off when the car comes to a stop, saving ...

  14. Revealing Compressed Stops Using High-Momentum Recoils

    E-Print Network [OSTI]

    Macaluso, Sebastian; Shih, David; Tweedie, Brock

    2015-01-01

    Searches for supersymmetric top quarks at the LHC have been making great progress in pushing sensitivity out to higher mass, but are famously plagued by gaps in coverage around lower-mass regions where the decay phase space is closing off. Within the common stop-NLSP / neutralino-LSP simplified model, the line in the mass plane where there is just enough phase space to produce an on-shell top quark remains almost completely unconstrained. Here, we show that is possible to define searches capable of probing a large patch of this difficult region, with S/B ~ 1 and significances often well beyond 5 sigma. The basic strategy is to leverage the large energy gain of LHC Run 2, leading to a sizable population of stop pair events recoiling against a hard jet. The recoil not only re-establishes a MET signature, but also leads to a distinctive anti-correlation between the MET and the recoil jet transverse vectors when the stops decay all-hadronically. Accounting for jet combinatorics, backgrounds, and imperfections in ...

  15. Empirical relations for nuclear stopping power F. S. Garnir-Monjoie

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    31 Empirical relations for nuclear stopping power F. S. Garnir-Monjoie Institut de Mathématiques, D, due to inelastic interaction with the target electrons, and the nuclear stopping power induced. The Lindhard, Scharff and Schiott theory (LSS theory) [1] shows that the nuclear stopping power is the same

  16. miRNA-205 affects infiltration and metastasis of breast cancer

    SciTech Connect (OSTI)

    Wang, Zhouquan; Department of Tumor, SenGong Hospital of Shaanxi, Xi’an 710300 ; Liao, Hehe; Deng, Zhiping; Yang, Po; Du, Ning; Zhanng, Yunfeng; Ren, Hong

    2013-11-08

    Highlights: •We detected expression of miR-205 in breast cancer cell lines and tissue samples. •We suggest miR-205 is downregulated in human breast cancer tissues and MCF7 cells. •We suggest the lower expression of miR-205 play a role in breast cancer onset. •These data suggest that miR-205 directly targets HER3 in human breast cancer. -- Abstract: Background: An increasing number of studies have shown that miRNAs are commonly deregulated in human malignancies, but little is known about the function of miRNA-205 (miR-205) in human breast cancer. The present study investigated the influence of miR-205 on breast cancer malignancy. Methods: The expression level of miR-205 in the MCF7 breast cancer cell line was determined by quantitative (q)RT-PCR. We then analyzed the expression of miR-205 in breast cancer and paired non-tumor tissues. Finally, the roles of miR-205 in regulating tumor proliferation, apoptosis, migration, and target gene expression were studied by MTT assay, flow cytometry, qRT-PCR, Western blotting and luciferase assay. Results: miR-205 was downregulated in breast cancer cells or tissues compared with normal breast cell lines or non-tumor tissues. Overexpression of miR-205 reduced the growth and colony-formation capacity of MCF7 cells by inducing apoptosis. Overexpression of miR-205 inhibited MCF7 cell migration and invasiveness. By bioinformation analysis, miR-205 was predicted to bind to the 3? untranslated regions of human epidermal growth factor receptor (HER)3 mRNA, and upregulation of miR-205 reduced HER3 protein expression. Conclusion: miR-205 is a tumor suppressor in human breast cancer by post-transcriptional inhibition of HER3 expression.

  17. miR-132, an experience-dependent microRNA, is essential for visual cortex plasticity

    E-Print Network [OSTI]

    Mellios, Nikolaos

    Using quantitative analyses, we identified microRNAs (miRNAs) that were abundantly expressed in visual cortex and that responded to dark rearing and/or monocular deprivation. The most substantially altered miRNA, miR-132, ...

  18. Capital mobility and sudden stops: consequences and policy options 

    E-Print Network [OSTI]

    Ball, Christopher Patrick

    2004-09-30

    and 1 It should also be noted that the crisis in Argentina later proved Calvo?s claims to be very accurate. 5 Mendoza (1996 and 2000b) develop a model of rational herding and contagion based on the notion that lenders bunch countries together... research is weak at best although Calvo, Izquierdo and Talvi (2002) contains some detailed empirical analysis for the case of Argentina and Calvo and Reinhart (2000) contains analysis on the overall bailout and GDP costs of many sudden stop crises...

  19. Your First Stop for Clean Energy Policy Support (Fact Sheet)

    SciTech Connect (OSTI)

    Not Available

    2012-06-01

    The Clean Energy Solutions Center, an initiative of the Clean Energy Ministerial and UN-Energy, helps governments design and adopt policies and programs that support the deployment of transformational low-carbon technologies. The Solutions Center serves as a first-stop clearinghouse of clean energy policy reports, data, and tools and provides expert assistance and peer-to-peer learning forums. This factsheet highlights key Solutions Center offerings, including 'ask an expert' assistance on clean energy policy matters, training and peer learning, and technical resources for policy makers worldwide.

  20. Effects of disabled vehicles stopped on a freeway shoulder 

    E-Print Network [OSTI]

    Wilshire, Roy Leon

    1963-01-01

    EFFECTS OF !3ISABLED VEHICLES STOPPFD ON A FREEWAY SHOULDER A Thesis ROY LEON WILSHIRE S" bmitted to tl-, e Graduate School of the Agricultural and Mechar. ical Col lege of Texas in partial fulfillment of the t equiremcnts for the degree... of MASTER OF SCIENCE August 1963 Major Subject; Cevil Engineering EFFECTS OF DISABLED VEHICLES STOPPED ON A FREEWAY SHOULDER A Thesis By ROY LEON WILSHIRE Approved as to style and content by: Chairman of Committee H ad of Department August 196 3...

  1. Semiempirical range and stopping power values for heavy ions 

    E-Print Network [OSTI]

    Schilling, Ralph Franklin, III

    1968-01-01

    and Graphs . . . 21 USE OF THE TABLES AND GRAPHS. . . . . . . 2$ VALIDITY OF SZii1IEviPIRICAL RESULTS. . . . 26 RZFZRZNCES. APPENDIX . . ~ ~ ~ ~, ~ ~ ~ 28 29 LIST OF FIGURES Stopping power curves for 1ons of various atomic numbers 1n Al. The energy... Uj U1 ~ ~ ~ y m I (D r r co ~ ~ ~ a NOND t(1 Q ~ ~ ~ ~ rn a I 4 lf', CJ a Nu ++O (T N 4' 0 In ~ 4 Ill ~ ~ ~ ~ ~ N QNONQ 0 0 nj Q' ~ ~ \\ ((1 Q Q ~ 4 W Gj Q ~l (T ocoa ~ rn a' 4 C' ~ N N N ((I C tn ~ ~ ~ N rh fn nJ 0 Nt 0 0 0 rn...

  2. Molecular Cell Loss of miR-200 Inhibition of Suz12 Leads to

    E-Print Network [OSTI]

    In an inducible oncogenesis model, the miR-200 family is inhibited during CSC formation but not trans- formation

  3. Discovery of miRNA-regulated processes in mammalian development

    E-Print Network [OSTI]

    Young, Amanda Garfinkel

    2010-01-01

    The genomes of plants and animals encode hundreds of non-coding ~22nt RNAs termed "microRNAs" (miRNAs). These RNAs guide the sequence-specific inhibition of translation and destabilization of mRNA targets through short ...

  4. A Member of The Texas A&M University System Reducing School Bus Stop-Arm Violations in Texas

    E-Print Network [OSTI]

    A Member of The Texas A&M University System Reducing School Bus Stop-Arm Violations in Texas Video Technology in Identifying School Bus Stop-Arm Violations #12;REDUCING SCHOOL BUS STOP-ARM in Identifying School Bus Stop-Arm Violations By Patricia A. Turner Associate Research Scientist Texas

  5. I am receiving my first bachelor's degree. (If you are receiving a second bachelor's or graduate degree, STOP, you are not eligible for the rebate.)

    E-Print Network [OSTI]

    Texas at San Antonio, University of

    degree, STOP, you are not eligible for the rebate.) I enrolled for the first time in an institution pursuing my bachelor's degree. If you qualify for the tuition rebate, the rebate shall first be applied may qualify for an increase in the amount of your rebate, not to exceed $1,000, by providing proof

  6. Forward Lambda Production and Nuclear Stopping Power in d+Au Collisions at RHIC

    E-Print Network [OSTI]

    Simon, F

    2005-01-01

    Using the forward time projection chambers of STAR we measure the centrality dependent Lambda and Anti-Lambda yields in d+Au collisions at \\sqrt{s_{NN} = 200 GeV at forward and backward rapidities. The contributions of different processes to particle production and baryon transport are probed exploiting the inherent asymmetry of the d+Au system. While the d side appears to be dominated by multiple independent nucleon-nucleon collisions, nuclear effects contribute significantly on the Au side. Using the constraint of baryon number conservation, the rapidity loss of baryons in the incoming deuteron can be estimated as a function of centrality. This is compared to a model and to similar measurements in Au+Au, which gives insights into the nuclear stopping power at relativistic energies.

  7. Forward Lambda Production and Nuclear Stopping Power in d+Au Collisions at RHIC

    E-Print Network [OSTI]

    Frank Simon; for the STAR collaboration

    2006-02-09

    Using the forward time projection chambers of STAR we measure the centrality dependent Lambda and Anti-Lambda yields in d+Au collisions at \\sqrt{s_{NN} = 200 GeV at forward and backward rapidities. The contributions of different processes to particle production and baryon transport are probed exploiting the inherent asymmetry of the d+Au system. While the d side appears to be dominated by multiple independent nucleon-nucleon collisions, nuclear effects contribute significantly on the Au side. Using the constraint of baryon number conservation, the rapidity loss of baryons in the incoming deuteron can be estimated as a function of centrality. This is compared to a model and to similar measurements in Au+Au, which gives insights into the nuclear stopping power at relativistic energies.

  8. AVTA: 2010 Volkswagon Golf Diesel Start-Stop Testing Results

    Broader source: Energy.gov [DOE]

    The Vehicle Technologies Office's Advanced Vehicle Testing Activity carries out testing on a wide range of advanced vehicles and technologies on dynamometers, closed test tracks, and on-the-road. These results provide benchmark data that researchers can use to develop technology models and guide future research and development. The following reports describe results of testing done on a 2010 Volkswagon Golf Diesel vehicle with stop-start technology. Baseline data, which provides a point of comparison for the other test results, was collected at two different research laboratories. Baseline and other data collected at Idaho National Laboratory is in the attached documents. Baseline and battery testing data collected at Argonne National Laboratory is available in summary and CSV form on the Argonne Downloadable Dynometer Database site (http://www.anl.gov/energy-systems/group/downloadable-dynamometer-databas...). Taken together, these reports give an overall view of how this vehicle functions under extensive testing.

  9. Repression of miR-17-5p with elevated expression of E2F-1 and c-MYC in non-metastatic hepatocellular carcinoma and enhancement of cell growth upon reversing this expression pattern

    SciTech Connect (OSTI)

    El Tayebi, H.M.; Omar, K.; Hegy, S.; El Maghrabi, M.; El Brolosy, M. [The Molecular Pathology Research Group, Department of Pharmacology and Toxicology, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo (Egypt)] [The Molecular Pathology Research Group, Department of Pharmacology and Toxicology, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo (Egypt); Hosny, K.A. [Department of General Surgery, Faculty of Medicine, Cairo University, Cairo (Egypt)] [Department of General Surgery, Faculty of Medicine, Cairo University, Cairo (Egypt); Esmat, G. [Department of Endemic Medicine and Hepatology, Cairo University, Cairo (Egypt)] [Department of Endemic Medicine and Hepatology, Cairo University, Cairo (Egypt); Abdelaziz, A.I., E-mail: ahmed.abdel-aziz@guc.edu.eg [The Molecular Pathology Research Group, Department of Pharmacology and Toxicology, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo (Egypt)

    2013-05-10

    Highlights: •The oncogenic miR-17-5p is downregulated in non-metastatic hepatocellular carcinoma patients. •E2F-1 and c-MYC transcripts are upregulated in non-metastatic HCC patients. •miR-17-5p forced overexpression inhibited E2F-1 and c-MYC expression in HuH-7 cells. •miR-17-5p mimicking increased HuH-7 cell growth, proliferation, migration and colony formation. •miR-17-5p is responsible for HCC progression among the c-MYC/E2F-1/miR-17-5p triad members. -- Abstract: E2F-1, c-MYC, and miR-17-5p is a triad of two regulatory loops: a negative and a positive loop, where c-MYC induces the expression of E2F-1 that induces the expression of miR-17-5p which in turn reverses the expression of E2F-1 to close the loop. In this study, we investigated this triad for the first time in hepatocellular carcinoma (HCC), where miR-17-5p showed a significant down-regulation in 23 non-metastatic HCC biopsies compared to 10 healthy tissues; however, E2F-1 and c-MYC transcripts were markedly elevated. Forced over-expression of miR-17-5p in HuH-7 cells resulted in enhanced cell proliferation, growth, migration and clonogenicity with concomitant inhibition of E2F-1 and c-MYC transcripts expressions, while antagomirs of miR-17-5p reversed these events. In conclusion, this study revealed a unique pattern of expression for miR-17-5p in non-metastatic HCC patients in contrast to metastatic HCC patients. In addition we show that miR-17-5p is the key player among the triad that tumor growth and spread.

  10. The MiMeS Survey of Magnetism in Massive Stars: Introduction and overview

    E-Print Network [OSTI]

    Wade, G A; Alecian, E; Grunhut, J H; Petit, V; de Batz, B; Bohlender, D A; Cohen, D H; Henrichs, H F; Kochukhov, O; Landstreet, J D; Manset, N; Martins, F; Mathis, S; Oksala, M E; Owocki, S P; Rivinius, Th; Shultz, M E; Sundqvist, J O; Townsend, R H D; ud-Doula, A; Bouret, J -C; Braithwaite, J; Briquet, M; Carciofi, A C; David-Uraz, A; Folsom, C P; Fullerton, A W; Leroy, B; Marcolino, W L F; Moffat, A F J; Nazé, Y; Aurière, M; Bagnulo, S; Bailey, J D; Barbá, R H; Blazère, A; Böhm, T; Catala, C; Donati, J -F; Ferrario, L; Harrington, D; Howarth, I D; Ignace, R; Kaper, L; Lüftinger, T; Prinja, R; Vink, J S; Weiss, W W; Yakunin, I

    2015-01-01

    The MiMeS project is a large-scale, high resolution, sensitive spectropolarimetric investigation of the magnetic properties of O and early B type stars. Initiated in 2008 and completed in 2013, the project was supported by 3 Large Program allocations, as well as various programs initiated by independent PIs and archival resources. Ultimately, over 4800 circularly polarized spectra of 560 O and B stars were collected with the instruments ESPaDOnS at the Canada-France-Hawaii Telescope, Narval at the T\\'elescope Bernard Lyot, and HARPSpol at the European Southern Observatory La Silla 3.6m telescope, making MiMeS by far the largest systematic investigation of massive star magnetism ever undertaken. In this paper, the first in a series reporting the general results of the survey, we introduce the scientific motivation and goals, describe the sample of targets, review the instrumentation and observational techniques used, explain the exposure time calculation designed to provide sensitivity to surface dipole fields...

  11. miR-153 and miR-335, Ethanol Sensitive MicroRNAs, Control NSC/NPC Maturation during Fetal Brain Development 

    E-Print Network [OSTI]

    Tsai, Pai Chi

    2014-05-05

    conclude that miR-335 and miR-153 act as molecular brakes to prevent NSCs/NPCs early maturation by regulating cell differentiation genes during the second trimester, and ethanol leads to organizational defects in the developing cerebral cortex through...

  12. Stopping of Light by the Dynamic Tuning of Photonic Crystal Slow Light Device

    E-Print Network [OSTI]

    Baba, Toshihiko

    Stopping of Light by the Dynamic Tuning of Photonic Crystal Slow Light Device Yuji Saito1-cho, Chiyodaku, Tokyo 102-0075, Japan *baba@ynu.ac.jp Abstract: We propose a simple technique of stopping light pulses using a slow-light device based on photonic crystal coupled waveguide (PCCW). Dynamically tuning

  13. Delayed Nondeterminism in Continuous-Time Markov Decision Processes

    E-Print Network [OSTI]

    Ábrahám, Erika

    have to come home by 6 pm. · On your way, you stop at a red traffic light. · When it turns green, you you have to come home by 6 pm. · On your way, you stop at a red traffic light. · When it turns green Motivation Continuous-Time Markov Decision Processes: An Example Imagine you have to come home by 6 pm

  14. DLEU2, frequently deleted in malignancy, functions as a critical host gene of the cell cycle inhibitory microRNAs miR-15a and miR-16-1

    SciTech Connect (OSTI)

    Lerner, Mikael; Harada, Masako; Loven, Jakob; Castro, Juan; Davis, Zadie; Oscier, David; Henriksson, Marie; Sangfelt, Olle; Grander, Dan; Corcoran, Martin M.

    2009-10-15

    The microRNAs miR-15a and miR-16-1 are downregulated in multiple tumor types and are frequently deleted in chronic lymphocytic leukemia (CLL), myeloma and mantle cell lymphoma. Despite their abundance in most cells the transcriptional regulation of miR-15a/16-1 remains unclear. Here we demonstrate that the putative tumor suppressor DLEU2 acts as a host gene of these microRNAs. Mature miR-15a/miR-16-1 are produced in a Drosha-dependent process from DLEU2 and binding of the Myc oncoprotein to two alterative DLEU2 promoters represses both the host gene transcript and levels of mature miR-15a/miR-16-1. In line with a functional role for DLEU2 in the expression of the microRNAs, the miR-15a/miR-16-1 locus is retained in four CLL cases that delete both promoters of this gene and expression analysis indicates that this leads to functional loss of mature miR-15a/16-1. We additionally show that DLEU2 negatively regulates the G1 Cyclins E1 and D1 through miR-15a/miR-16-1 and provide evidence that these oncoproteins are subject to miR-15a/miR-16-1-mediated repression under normal conditions. We also demonstrate that DLEU2 overexpression blocks cellular proliferation and inhibits the colony-forming ability of tumor cell lines in a miR-15a/miR-16-1-dependent way. Together the data illuminate how inactivation of DLEU2 promotes cell proliferation and tumor progression through functional loss of miR-15a/miR-16-1.

  15. Groundwater protection for the NuMI project

    SciTech Connect (OSTI)

    Wehmann, A.; Smart, W.; Menary, S.; Hylen, J.; Childress, S.

    1997-10-01

    The physics requirements for the long base line neutrino oscillation experiment MINOS dictate that the NuMI beamline be located in the aquifer at Fermilab. A methodology is described for calculating the level of radioactivation of groundwater caused by operation of this beamline. A conceptual shielding design for the 750 meter long decay pipe is investigated which would reduce radioactivation of the groundwater to below government standards. More economical shielding designs to meet these requirements are being explored. Also, information on local geology, hydrogeology, government standards, and a glossary have been included.

  16. DOE - Office of Legacy Management -- Star Cutter Corp - MI 15

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouth DakotaRobbins and Myers Co - OHStar Cutter Corp - MI 15 FUSRAP

  17. DOE - Office of Legacy Management -- Westinghouse Naval Ordnance - MI 02

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouth DakotaRobbins and Myers Co -VANaval Ordnance - MI 02 FUSRAP

  18. DOE - Office of Legacy Management -- Wolverine Tube Division - MI 05

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouth DakotaRobbins and Myers Co -VANaval Ordnance - MI

  19. REC Silicon formerly ASiMI | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page onRAPID/Geothermal/Exploration/Colorado <RAPID/Geothermal/Water Use/NevadaaTools < RAPID79.14Silicon formerly ASiMI

  20. MHK Technologies/Mi2 | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION J APPENDIXsource HistoryScenarios Towards 2050Enermar < MHKHydro HelixLangleeMi2 < MHK

  1. Automatic generation of stop word lists for information retrieval and analysis

    DOE Patents [OSTI]

    Rose, Stuart J

    2013-01-08

    Methods and systems for automatically generating lists of stop words for information retrieval and analysis. Generation of the stop words can include providing a corpus of documents and a plurality of keywords. From the corpus of documents, a term list of all terms is constructed and both a keyword adjacency frequency and a keyword frequency are determined. If a ratio of the keyword adjacency frequency to the keyword frequency for a particular term on the term list is less than a predetermined value, then that term is excluded from the term list. The resulting term list is truncated based on predetermined criteria to form a stop word list.

  2. Study of stopping power for a proton moving in a plasma with arbitrary degeneracy

    SciTech Connect (OSTI)

    Zhang, Ya; Song, Yuan-Hong; Wang, You-Nian [School of Physics and Optoelectronic Technology, Dalian University of Technology, Dalian 116024 (China)] [School of Physics and Optoelectronic Technology, Dalian University of Technology, Dalian 116024 (China)

    2013-10-15

    Excitation of bulk solid electrons with arbitrary degeneracy, by external charged particles, is investigated by a two-dimensional nonlinear quantum hydrodynamic (QHD) model. The nonlinear stopping power and wake potential are calculated by solving the nonlinear QHD equations with the flux corrected transport numerical method. Two cases of fully degenerated and partially degenerated electrons are compared and discussed in the same self-consistent QHD model. Our results are consistent with the well known dielectric calculation of the stopping power at higher velocity, but include the nonlinear terms of the interactions and give larger stopping power at smaller velocity.

  3. Long-lived stop at the LHC with or without R-parity

    SciTech Connect (OSTI)

    Covi, L.; Dradi, F., E-mail: laura.covi@theorie.physik.uni-goettingen.de, E-mail: federico.dradi@theorie.physik.uni-goettingen.de [Institut für Theoretische Physik, Friedrich-Hund-Platz 1, 37077 Göttingen (Germany)

    2014-10-01

    We consider scenarios of gravitino LSP and DM with stop NLSP both within R-parity conserving and R-parity violating supersymmetry (RPC and RPV SUSY, respectively). We discuss cosmological bounds from Big Bang Nucleosynthesis (BBN) and the gravitino abundance and then concentrate on the signals of long-lived stops at the LHC as displaced vertices or metastable particles. Finally we discuss how to distinguish R-parity conserving and R-parity breaking stop decays if they happen within the detector and how to suppress SM backgrounds.

  4. Letter to Financial Times, February 5, 2015 Stop blathering and give

    E-Print Network [OSTI]

    , My reaction upon reading Eugene Rumer's article "Arm Ukraine and you risk another Black Hawk Down which it labours. Just give Ukraine the military aid it asks for, and let the Ukrainians do the rest

  5. Unraveling resistive versus collisional contributions to relativistic electron beam stopping power in cold-solid and in warm-dense plasmas

    SciTech Connect (OSTI)

    Vauzour, B.; Laboratoire d'Optique Appliquée, ENSTA-CNRS-Ecole Polytechnique, UMR 7639, 91761 Palaiseau ; Debayle, A.; CEA, DAM, DIF, F-91297 Arpajon ; Vaisseau, X.; Hulin, S.; Nicolaï, Ph.; Dorchies, F.; Fourment, C.; D'Humières, E.; Tikhonchuk, V. T.; Santos, J. J.; Schlenvoigt, H.-P.; Baton, S. D.; Yahia, V.; Dipartimento di Fisica, Università di Milano-Bicocca, Milano 20126 ; Honrubia, J. J.; Beg, F. N.; Chawla, S.; Jarrot, L. C.; Benocci, R.; Volpe, L.; and others

    2014-03-15

    We present results on laser-driven relativistic electron beam propagation through aluminum samples, which are either solid and cold or compressed and heated by laser-induced shock. A full numerical description of fast electron generation and transport is found to reproduce the experimental absolute K{sub ?} yield and spot size measurements for varying target thicknesses, and to sequentially quantify the collisional and resistive electron stopping powers. The results demonstrate that both stopping mechanisms are enhanced in compressed Al samples and are attributed to the increase in the medium density and resistivity, respectively. For the achieved time- and space-averaged electronic current density, ?j{sub h}??8×10{sup 10}?A/cm{sup 2} in the samples, the collisional and resistive stopping powers in warm and compressed Al are estimated to be 1.5?keV/?m and 0.8?keV/?m, respectively. By contrast, for cold and solid Al, the corresponding estimated values are 1.1?keV/?m and 0.6?keV/?m. Prospective numerical simulations involving higher j{sub h} show that the resistive stopping power can reach the same level as the collisional one. In addition to the effects of compression, the effect of the transient behavior of the resistivity of Al during relativistic electron beam transport becomes progressively more dominant, and for a significantly high current density, j{sub h}?10{sup 12}?A/cm{sup 2}, cancels the difference in the electron resistive stopping power (or the total stopping power in units of areal density) between solid and compressed samples. Analytical calculations extend the analysis up to j{sub h}=10{sup 14}?A/cm{sup 2} (representative of the full-scale fast ignition scenario of inertial confinement fusion), where a very rapid transition to the Spitzer resistivity regime saturates the resistive stopping power, averaged over the electron beam duration, to values of ?1?keV/?m.

  6. Heavy standard model-like Higgs boson and a light stop fromYukawa...

    Office of Scientific and Technical Information (OSTI)

    Journal Article: Heavy standard model-like Higgs boson and a light stop from Yukawa-deflected gauge mediation Citation Details In-Document Search Title: Heavy standard model-like...

  7. DOE Takes Action to Stop the Sales of Air-Con Air Conditioner...

    Broader source: Energy.gov (indexed) [DOE]

    against Air-Con, International, requiring the company to stop selling certain air conditioning systems in the U.S. that have been shown to violate minimum energy efficiency...

  8. Pneumatic brake control for precision stopping of heavy-duty vehicles

    E-Print Network [OSTI]

    Bu, Fanping; Tan, Han-Shue

    2007-01-01

    stopping” of a 40 foot CNG bus for the Bus Precision Dockingfor two different 40 foot CNG buses (c1 and c2). Althoughpressure of two different CNG buses (c1 and c2) speeds since

  9. SAFETY EFFECTIVENESS OF STOP CONTROL AT ULTRA-LOW VOLUME UNPAVED INTERSECTIONS

    E-Print Network [OSTI]

    Carriquiry, Alicia

    , unpaved intersections in Iowa comparing stop to no-control. Crash models were developed using logistic to potential liability for deficient maintenance. However, no published guidelines for removal of unneeded two

  10. Vehicle Technologies Office Merit Review 2015: A 12V Start-Stop Li Polymer Battery Pack

    Broader source: Energy.gov [DOE]

    Presentation given by LG Chem Power at 2015 DOE Hydrogen and Fuel Cells Program and Vehicle Technologies Office Annual Merit Review and Peer Evaluation Meeting about A 12V start-stop Li polymer...

  11. An evaluation of supplemental signing at two-way stop-controlled intersections 

    E-Print Network [OSTI]

    Schuckel, Clint Edwin

    1996-01-01

    NOT STOP." The objective of this thesis was to investigate the effectiveness of these signs in reducing conflicts and accidents at TWSC intersections. Traffic conflict and accident data were obtained for six TWSC intersections in Texas; three locations...

  12. Information Please return to ITS Support Center, Mail Stop: ITS Kerr University Administrative Information System

    E-Print Network [OSTI]

    California at Santa Cruz, University of

    Information Please return to ITS Support Center, Mail Stop: ITS Kerr Technology Services University Number Records Retention Information: Information Technology Services Retention Period: 5 years after Administrative Information System ACCESS TO INFORMATION STATEMENT Federal law, California law, and University

  13. Evidence of abundant stop codon readthrough in Drosophila and other Metazoa

    E-Print Network [OSTI]

    Jungreis, Irwin

    While translational stop codon readthrough is often used by viral genomes, it has been observed for only a handful of eukaryotic genes. We previously used comparative genomics evidence to recognize protein-coding regions ...

  14. An acoustic and aerodynamic study of stops in tonal and non-tonal dialects of Korean

    E-Print Network [OSTI]

    Lee, Hyunjung

    2010-03-29

    ABSTRACT This study investigates the acoustic and aerodynamic properties of well&ndashknown three&ndashway distinction of Korean voiceless stops in two dialects, which differ in their tonal systems: non&ndashtonal Seoul Korean (standard Korean...

  15. Hepatitis C Virus Infection and Hepatic Stellate Cell Activation Downregulate miR-29: miR-29 Overexpression Reduces Hepatitis C Viral Abundance in Culture

    E-Print Network [OSTI]

    Bandyopadhyay, Sarmistha

    Background.?Chronic hepatitis C virus (HCV)–induced liver fibrosis involves upregulation of transforming growth factor (TGF)–? and subsequent hepatic stellate cell (HSC) activation. MicroRNAs (miRNAs) regulate HCV infection ...

  16. Method and apparatus for rapid stopping and starting of a thermoacoustic engine

    SciTech Connect (OSTI)

    Swift, Gregory W.; Backhaus, Scott N.; Gardner, David L.

    2003-11-11

    A thermoacoustic engine-driven system with a hot heat exchanger, a regenerator or stack, and an ambient heat exchanger includes a side branch load for rapid stopping and starting, the side branch load being attached to a location in the thermoacoustic system having a nonzero oscillating pressure and comprising a valve, a flow resistor, and a tank connected in series. The system is rapidly stopped simply by opening the valve and rapidly started by closing the valve.

  17. Reducing or stopping the uncontrolled flow of fluid such as oil from a well

    DOE Patents [OSTI]

    Hermes, Robert E

    2014-02-18

    The uncontrolled flow of fluid from an oil or gas well may be reduced or stopped by injecting a composition including 2-cyanoacrylate ester monomer into the fluid stream. Injection of the monomer results in a rapid, perhaps instantaneous, polymerization of the monomer within the flow stream of the fluid. This polymerization results in formation of a solid plug that reduces or stops the flow of additional fluid from the well.

  18. Validation of the MCNPX-PoliMi Code to Design a Fast-Neutron Multiplicity Counter

    SciTech Connect (OSTI)

    J. L. Dolan; A. C. Kaplan; M. Flaska; S. A. Pozzi; D. L. Chichester

    2012-07-01

    Many safeguards measurement systems used at nuclear facilities, both domestically and internationally, rely on He-3 detectors and well established mathematical equations to interpret coincidence and multiplicity-type measurements for verifying quantities of special nuclear material. Due to resource shortages alternatives to these existing He-3 based systems are being sought. Work is also underway to broaden the capabilities of these types of measurement systems in order to improve current multiplicity analysis techniques. As a part of a Material Protection, Accounting, and Control Technology (MPACT) project within the U.S. Department of Energy's Fuel Cycle Technology Program we are designing a fast-neutron multiplicity counter with organic liquid scintillators to quantify important quantities such as plutonium mass. We are also examining the potential benefits of using fast-neutron detectors for multiplicity analysis of advanced fuels in comparison with He-3 detectors and testing the performance of such designs. The designs are being developed and optimized using the MCNPX-PoliMi transport code to study detector response. In the full paper, we will discuss validation measurements used to justify the use of the MCNPX-PoliMi code paired with the MPPost multiplicity routine to design a fast neutron multiplicity counter with liquid scintillators. This multiplicity counter will be designed with the end goal of safeguarding advanced nuclear fuels. With improved timing qualities associated with liquid scintillation detectors, we can design a system that is less limited by nuclear materials of high activities. Initial testing of the designed system with nuclear fuels will take place at Idaho National Laboratory in a later stage of this collaboration.

  19. Global identification of miRNAs and targets in Populus euphratica under salt stress

    E-Print Network [OSTI]

    Deng, Xing-Wang

    Global identification of miRNAs and targets in Populus euphratica under salt stress Bosheng Li, a typical hydro-halophyte, is ideal for studying salt stress responses in woody plants. MicroRNAs (miRNA may regulate tolerance to salt stress but this has not been widely studied in P. euphratica

  20. Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres

    E-Print Network [OSTI]

    Ji, Qing; Hao, Xinbao; Meng, Yang; Zhang, Min; DeSano, Jeffrey; Fan, Daiming; Xu, Liang

    2008-09-21

    Background: MicroRNAs (miRNAs), some of which function as oncogenes or tumor suppressor genes, are involved in carcinogenesis via regulating cell proliferation and/or cell death. MicroRNA miR-34 was recently found to be a direct target of p53...

  1. Precision Timing Via Cerenkov Radiation,

    E-Print Network [OSTI]

    McDonald, Kirk

    ) beam splitter EG&G Ortec 9306 EG&G Ortec 9306 Microchannel­plate Photo Multiplier (MCP­PMT) 1 GHz Preamplifier Semiconductor Photo Diode 1 GHz Preamplifier EG&G Ortec 9307 EG&G Ortec 9307 ``Pico Timing Converter (TAC) 10 ns delay Stop Start Multi Channel Analyzer (MCA) beam splitter EG&G Ortec 9306 1 GHz

  2. Mi2beta Is Required for c-Globin Gene Silencing: Temporal Assembly of a GATA-1-FOG-1-Mi2 Repressor Complex in b-YAC Transgenic Mice

    E-Print Network [OSTI]

    Costa, Flá via C.; Fedosyuk, Halyna; Chazelle, Allen M.; Neades, Renee Y.; Peterson, Kenneth R.

    2012-12-20

    Mi2b Is Required for c-Globin Gene Silencing: Temporal Assembly of a GATA-1-FOG-1-Mi2 Repressor Complex in b-YAC Transgenic Mice Fla´via C. Costa1¤, Halyna Fedosyuk1, Allen M. Chazelle1, Renee Y. Neades1, Kenneth R. Peterson1,2* 1Department... hemoglobin. A GATA-1-FOG-1-Mi2 repressor complex was recently demonstrated to be recruited to the 2566 GATA motif of the Ac-globin gene. We show that Mi2b is essential for c-globin gene silencing using Mi2b conditional knockout b-YAC transgenic mice...

  3. miR-128 and its target genes in tumorigenesis and metastasis

    SciTech Connect (OSTI)

    Li, Molin, E-mail: molin_li@hotmail.com [Dalian Medical University, Dalian 116044 (China); Fu, Weiming [Center for Food Safety and Environmental Technology, Guangzhou Institute of Advanced Technology, Chinese Academy of Sciences, Guangzhou 511458 (China); Wo, Lulu; Shu, Xiaohong [Dalian Medical University, Dalian 116044 (China); Liu, Fang [The second affiliated hospital of Dalian Medical University, Dalian 116023 (China); Li, Chuangang, E-mail: li_chuangang@sina.com [The second affiliated hospital of Dalian Medical University, Dalian 116023 (China)

    2013-12-10

    MicroRNAs (miRNAs) are a class of endogenous, non-coding, 18–24 nucleotide length single-strand RNAs that could modulate gene expression at post-transcriptional level. Previous studies have shown that miR-128 enriched in the brain plays an important role in the development of nervous system and the maintenance of normal physical functions. Aberrant expression of miR-128 has been detected in many types of human tumors and its validated target genes are involved in cancer-related biological processes such as cell proliferation, differentiation and apoptosis. In this review, we will summarize the roles of miR-128 and its target genes in tumorigenesis and metastasis. - Highlights: • Aberrant expression of miR-128 can be observed in many kinds of malignant tumors. • The molecular mechanisms regulating miR-128 expression are elucidated. • Roles of miR-128 and its target genes in tumorigenesis and metastasis are summarized.

  4. Light Stops, Light Staus and the 125 GeV Higgs

    SciTech Connect (OSTI)

    Carena, Marcela; Gori, Stefania; Shah, Nausheen R.; Wagner, Carlos E.M.; Wang, Lian-Tao

    2013-08-01

    The ATLAS and CMS experiments have recently announced the discovery of a Higgs-like resonance with mass close to 125 GeV. Overall, the data is consistent with a Standard Model (SM)-like Higgs boson. Such a particle may arise in the minimal supersymmetric extension of the SM with average stop masses of the order of the TeV scale and a sizable stop mixing parameter. In this article we discuss properties of the SM-like Higgs production and decay rates induced by the possible presence of light staus and light stops. Light staus can affect the decay rate of the Higgs into di-photons and, in the case of sizable left-right mixing, induce an enhancement in this production channel up to $\\sim$ 50% of the Standard Model rate. Light stops may induce sizable modifications of the Higgs gluon fusion production rate and correlated modifications to the Higgs diphoton decay. Departures from SM values of the bottom-quark and tau-lepton couplings to the Higgs can be obtained due to Higgs mixing effects triggered by light third generation scalar superpartners. We describe the phenomenological implications of light staus on searches for light stops and non-standard Higgs bosons. Finally, we discuss the current status of the search for light staus produced in association with sneutrinos, in final states containing a $W$ gauge boson and a pair of $\\tau$s.

  5. Light Stops and Observation of Supersymmetry at LHC RUN-II

    E-Print Network [OSTI]

    Kaufman, Bryan; Nelson, Brent D; Spisak, Andrew

    2015-01-01

    Light stops consistent with the Higgs boson mass of $\\sim126\\,{\\rm GeV}$ are investigated within the framework of minimal supergravity. It is shown that models with light stops which are also consistent with the thermal relic density constraints require stop coannihilation with the neutralino LSP. The analysis shows that the residual set of parameter points with light stops satisfying both the Higgs mass and the relic density constraints lie within a series of thin strips in the $m_0-m_{1/2}$ plane for different values of $A_0/m_0$. Consequently, this region of minimal supergravity parameter space makes a number of very precise predictions. It is found that light stops of mass down to 400~GeV or lower can exist consistent with all constraints. A signal analysis for this class of models at LHC RUN-II is carried out and the dominant signals for their detection identified. Also computed is the minimum integrated luminosity for $5\\sigma$ discovery of the models analyzed. If supersymmetry is realized in this manne...

  6. Light Stops in a minimal U(1)x extension of the MSSM

    E-Print Network [OSTI]

    Capdevilla, R M; Martin, A

    2015-01-01

    In order to reproduce the measured mass of the Higgs boson mh = 125GeV in the minimal supersymmetric standard model, one usually has to rely on heavy stops, increasing the fine tuning of the electroweak scale. By introducing a new gauge sector, the Higgs mass gets a tree-level contribution via a non-decoupling D-term, and mh = 125 GeV can be obtained with lighter stops. In this paper, we study the values of the stops masses needed to achieve the correct Higgs mass in a setup where the gauge group is extended by a single U(1)x interaction. We derive the experimental limits on the mass of the Z' gauge boson in this setup, then discuss how the stops masses vary as a function of the free parameters introduced by the new sector. We find that the correct Higgs mass can be reproduced with stops in a region between 700 - 800 GeV and a Z' resonance close to the 2.5 TeV bound from the run-I of the LHC, or in a higher region 800 - 900 GeV if the Z' resonance is heavier (3.1 TeV). This region of parameter space will be q...

  7. MiR-150, A Novel and Potent Regulator for MLL-AF9 Leukemic Stem Cells 

    E-Print Network [OSTI]

    Cheruku, Patali

    2013-02-18

    Designing the miR-150 sponge primer set .................................................................. 10 Preparation of the DNA fragment containing the miR-150 sponge sequence ............ 10 Construction of pcDNA5-CMV-d2eGFP-miR150sp... protocol. Enzymatic digestion with XhoI and ApaI confirmed the insertion of the miR-150 sponge fragment. The miR-150sp-eGFP sequence (Figure 1) was then amplified using polymerase chain reaction (PCR) with the BamHI forward and SalI reverse primers, gel...

  8. Knowing when to stop : the investigation of Flight 191

    E-Print Network [OSTI]

    Vatz, Mara E., 1980-

    2004-01-01

    On May 25, 1979, an American Airlines DC-10 crashed just after taking off from Chicago's O'Hare Airport. It was the worst crash in U.S. history at the time, having killed all 271 people on board and two people on the ground. ...

  9. Fact #853 December 29, 2014 Stop/Start Technology is in nearly 5% of All New Light Vehicles Produced- Dataset

    Broader source: Energy.gov [DOE]

    Excel file with dataset for Fact #853: December  29, 2014 Stop/Start Technology is in nearly 5% of All New Light Vehicles Produced

  10. Daily Modulation as a Smoking Gun of Dark Matter with Significant Stopping

    E-Print Network [OSTI]

    Chris Kouvaris; Ian M. Shoemaker

    2015-04-01

    We point out that for a range of parameters, the flux of DM may be stopped significantly by its interactions with the Earth. This can significantly degrade the sensitivity of direct detection experiments to DM candidates with large interactions with terrestrial nuclei. We find that a significant region of parameter space remains unconstrained for DM $\\lesssim $ a few GeV. For DM candidates with moderate levels of stopping power, the flux of DM may be blocked from below but not above a detector thereby producing a novel daily modulation. This can be explored by low threshold detectors placed on the surface or in shallow sites in the south hemisphere.

  11. Computer-Generated Papercutting Jie Xu1 Craig S. Kaplan1 Xiaofeng Mi2

    E-Print Network [OSTI]

    Waterloo, University of

    Computer-Generated Papercutting Jie Xu1 Craig S. Kaplan1 Xiaofeng Mi2 1Computer Graphics Lab David Pattern #12;Related Work Kaplan and Salesin, TOG 2004 Kaplan, GI 2005 #12;Geometric Patterns Geometric

  12. Modulation of Ago-miRNA regulatory networks by cis-sequence elements and target competition

    E-Print Network [OSTI]

    Bosson, Andrew D. (Andrew David)

    2014-01-01

    regulators of gene expression in a wide range of organisms and biological processes. Each miRNA guides Argonaute (Ago) protein complexes to target and repress hundreds of genes in a sequence-dependent manner. To identify ...

  13. Los Alamos Using Neutrons to Stop Nuclear Smugglers

    SciTech Connect (OSTI)

    Favalli, Andrea; Swinhoe, Martyn

    2013-06-03

    Los Alamos National Laboratory researchers have successfully demonstrated for the first time that laser-generated neutrons can be enlisted as a useful tool in the War on Terror. The international research team used the short-pulse laser at Los Alamos's TRIDENT facility to generate a neutron beam with novel characteristics that interrogated a closed container to confirm the presence and quantity of nuclear material inside. The successful experiment paves the way for creation of a table-top-sized or truck-mounted neutron generator that could be installed at strategic locations worldwide to thwart smugglers trafficking in nuclear materials.

  14. Los Alamos Using Neutrons to Stop Nuclear Smugglers

    ScienceCinema (OSTI)

    Favalli, Andrea; Swinhoe, Martyn

    2014-06-02

    Los Alamos National Laboratory researchers have successfully demonstrated for the first time that laser-generated neutrons can be enlisted as a useful tool in the War on Terror. The international research team used the short-pulse laser at Los Alamos's TRIDENT facility to generate a neutron beam with novel characteristics that interrogated a closed container to confirm the presence and quantity of nuclear material inside. The successful experiment paves the way for creation of a table-top-sized or truck-mounted neutron generator that could be installed at strategic locations worldwide to thwart smugglers trafficking in nuclear materials.

  15. The ArgoNeuT Detector in the NuMI Low-Energy beam line at Fermilab

    E-Print Network [OSTI]

    C. Anderson; M. Antonello; B. Baller; T. Bolton; C. Bromberg; F. Cavanna; E. Church; D. Edmunds; A. Ereditato; S. Farooq; B. Fleming; H. Greenlee; R. Guenette; S. Haug; G. Horton-Smith; C. James; E. Klein; K. Lang; A. Lathrop; P. Laurens; S. Linden; D. McKee; R. Mehdiyev; B. Page; O. Palamara; K. Partyka; S. Pordes; G. Rameika; B. Rebel; B. Rossi; R. Sanders; M. Soderberg; J. Spitz; A. M. Szelc; M. Weber; T. Yang; T. Wongjirad; G. Zeller

    2012-06-05

    The ArgoNeuT liquid argon time projection chamber has collected thousands of neutrino and antineutrino events during an extended run period in the NuMI beam-line at Fermilab. This paper focuses on the main aspects of the detector layout and related technical features, including the cryogenic equipment, time projection chamber, read-out electronics, and off-line data treatment. The detector commissioning phase, physics run, and first neutrino event displays are also reported. The characterization of the main working parameters of the detector during data-taking, the ionization electron drift velocity and lifetime in liquid argon, as obtained from through-going muon data complete the present report.

  16. Stop and Restart Effects on Modern Vehicle Starting System Components

    SciTech Connect (OSTI)

    Windover, Paul R.; Owens, Russell J.; Levinson, Terry M.; Laughlin, Michael; Gaines, Linda

    2015-01-01

    Many drivers of personal and commercial vehicles believe that turning the vehicle off and on frequently instead of idling will cause premature wear of the starter system (starter motor and starter battery). As a result, they are concerned that the replacement cost of the starter motor and/or battery due to increased manual engine cycling would be more than the cumulative cost of the fuel saved by not idling unnecessarily. A number of variables play a role in addressing this complex concern, including the number of starting cycles per day, the time between starting cycles, the intended design life of the starting system, the amount of fuel used to restart an engine, and the cumulative cost of the saved fuel. Qualitative and quantitative information from a variety of sources was used to develop a life-cycle economic model to evaluate the cost and quantify the realistic factors that are related to the permissible frequency of starter motor cycles for the average vehicle to economically minimize engine idle time. Annual cost savings can be calculated depending on shutdown duration and the number of shutdown cycles per day. Analysis shows that cost savings are realized by eliminating idling exceeding one minute by shutting down the engine and restarting it. For a typical motorist, the damage to starting system components resulting from additional daily start cycles will be negligible. Overall, it was found that starter life is mostly dependent on the total number of start cycles, while battery life is more dependent on ensuring a full charge between start events.

  17. C-Myc negatively controls the tumor suppressor PTEN by upregulating miR-26a in glioblastoma multiforme cells

    SciTech Connect (OSTI)

    Guo, Pin; Nie, Quanmin; Lan, Jin; Ge, Jianwei [Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127 (China)] [Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127 (China); Qiu, Yongming, E-mail: qiuzhoub@hotmail.com [Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127 (China) [Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127 (China); Shanghai Institute of Head Trauma, Shanghai 200127 (China); Mao, Qing, E-mail: maoq@netease.com [Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127 (China) [Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127 (China); Shanghai Institute of Head Trauma, Shanghai 200127 (China)

    2013-11-08

    Highlights: •The c-Myc oncogene directly upregulates miR-26a expression in GBM cells. •ChIP assays demonstrate that c-Myc interacts with the miR-26a promoter. •Luciferase reporter assays show that PTEN is a specific target of miR-26a. •C-Myc–miR-26a suppression of PTEN may regulate the PTEN/AKT pathway. •Overexpression of c-Myc enhances the proliferative capacity of GBM cells. -- Abstract: The c-Myc oncogene is amplified in many tumor types. It is an important regulator of cell proliferation and has been linked to altered miRNA expression, suggesting that c-Myc-regulated miRNAs might contribute to tumor progression. Although miR-26a has been reported to be upregulated in glioblastoma multiforme (GBM), the mechanism has not been established. We have shown that ectopic expression of miR-26a influenced cell proliferation by targeting PTEN, a tumor suppressor gene that is inactivated in many common malignancies, including GBM. Our findings suggest that c-Myc modulates genes associated with oncogenesis in GBM through deregulation of miRNAs via the c-Myc–miR-26a–PTEN signaling pathway. This may be of clinical relevance.

  18. An improved bus signal priority system for networks with nearside bus stops 

    E-Print Network [OSTI]

    Kim, Wonho

    2005-02-17

    -33 Average control delay per vehicle at the intersections, MOE5, under various headway levels ................................................................170 Table 7-34 Results of Duncan test for percentage change in MOE5 under various headway... ...................................................................................................55 x ...................................................................................................................................... Page Figure 4-2 Observed and predicted passenger arrival during off peak period at stop A...

  19. OPTIMAL STOPPING PROBLEMS FOR ASSET MANAGEMENT SAVAS DAYANIK AND MASAHIKO EGAMI

    E-Print Network [OSTI]

    Dayanik, Savas

    a nonanticipative stopping rule which maximizes her expected discounted total income. Under the original contract on a numerical example. The motivation comes from the collateralized debt obligations. 1. Introduction We study are motivated by those faced by the managers responsible for the portfolios of defaultable bonds, for example

  20. OPTIMAL STOPPING PROBLEMS FOR ASSET MANAGEMENT SAVAS DAYANIK AND MASAHIKO EGAMI

    E-Print Network [OSTI]

    Egami, Masahiko

    a nonanticipative stopping rule which maximizes her expected discounted total income. Under the original contract them on an example. The motivation comes from the collateralized debt obligations. 1. Introduction We are motivated by those faced by the managers responsible for the portfolios of defaultable bonds, for example

  1. Measurement of Charged-Particle Stopping in Warm Dense Plasma A. B. Zylstra,1,*

    E-Print Network [OSTI]

    Science and Fusion Center, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA 2 to cold matter, consistent with a reduced mean ionization potential. The data agree with stopping models fusion. Dense plasmas in the warm-dense matter (WDM) regime, approx- imately solid density and tens of e

  2. Effects of oil charge on illite dates and stopping quartz cement: calibration of basin models

    E-Print Network [OSTI]

    Haszeldine, Stuart

    Abstract Effects of oil charge on illite dates and stopping quartz cement: calibration of basin Oil can fill pores in reservoir sandstones at any burial depth by long or short distance migration. There has been a debate since 1920 concerning the effect of oil charge. We have made detailed local

  3. Vehicle Technologies Office: AVTA- Start-Stop (Micro) Hybrid Vehicles Performance Data

    Broader source: Energy.gov [DOE]

    The Advanced Vehicle Testing Activity (AVTA) uses standard procedures and test specifications to test and collect data from vehicles on dynamometers, closed test tracks, and on-the-road. Performance and testing data on the stop-start hybrid versions of the following vehicles is available: 2010 Smart Fortwo, 2010 Volkswagen Golf Diesel, and 2010 Mazda3 Hatchback.

  4. Toward On-line Schema Evolution for Non-stop Amol Deshpande and Michael Hicks

    E-Print Network [OSTI]

    Hicks, Michael

    in the third issue. Supporting on-line evolution is non-trivial. Almost every aspect of a running database and process of on-line schema evolution more concrete, we present an example inspired by http://www.agiledata.org/essays/databaseToward On-line Schema Evolution for Non-stop Systems Amol Deshpande and Michael Hicks University

  5. Planetary migration in a planetesimal disk: why did Neptune stop at 30 AU?

    E-Print Network [OSTI]

    Levison, Harold F.

    Planetary migration in a planetesimal disk: why did Neptune stop at 30 AU? Rodney S. Gomes GEA 12 gures #12;{ 2 { Running head: Migration in a planetesimal disk Send correspondence to: Rodney S, Brazil Received accepted #12;{ 3 { ABSTRACT We study planetary migration in a gas-free disk

  6. Heart stopping moments with zebrafish: imaging inside the living, beating heart

    E-Print Network [OSTI]

    Greenaway, Alan

    Heart stopping moments with zebrafish: imaging inside the living, beating heart Seamless this application, enabling researchers to carry out precision "healing" studies on the moving heart by targeting of development Jonathan M. Taylor, Glasgow University d "Realtime Optical Gating for 3D Heart Imaging", Journal

  7. Protein Fold Class Prediction using Neural Networks with Tailored Early-Stopping

    E-Print Network [OSTI]

    Igel, Christian

    Protein Fold Class Prediction using Neural Networks with Tailored Early-Stopping Thomas fold class given the primary sequence of a protein. Different feature spaces for primary sequences the fold class of proteins [8], [9], [10], [11], [12], [13], [14], [15], [16], [17]. A fold class contains

  8. Begin at the City Bakery (1318 E. 3rd). Stop in for a cup of

    E-Print Network [OSTI]

    Indiana University

    Begin at the City Bakery (1318 E. 3rd). Stop in for a cup of coffee and a tasty croissant, or enjoy Bookstore (1302 E. 3rd), where you can purchase textbooks or IU gear for yourself or family members. TIS (not easy to do on the IU campus), the Atwater Parking Garage is just south of 3rd between Faculty

  9. Post-exposure administration of diazepam combined with soluble epoxide hydrolase inhibition stops seizures and modulates

    E-Print Network [OSTI]

    Hammock, Bruce D.

    Post-exposure administration of diazepam combined with soluble epoxide hydrolase inhibition stops, investigated the effects of post-exposure administration of diaz- epam, a GABAAR positive allosteric modulator (0.15 mg/kg, ip). Administration of a high dose of diazepam (5 mg/kg, ip) immediately following

  10. Design and Analysis of Muon Beam Stop Support Structures

    SciTech Connect (OSTI)

    Okafor, Udenna

    2015-01-01

    The primary objective of this thesis is to design and analyze support structures to be used in the installation, test and final positioning of the MBS throughout the life of the Mu2e experiment. There several requirements for the MBS imposed by both the scope of the experiment and, other components within the DS bore. The functions of the MBS are: 1. To limit the induced rates in the Tracker, the Calorimeter and the Cosmic Ray Veto due to backsplash-and-secondary interactions, and 2. To reduce radiation levels external to the Detector solenoid. The structures used in supporting the MBS will also adhere to requirements imposed by its functions. These requirements are critical to the support structures and affect design decisions. Other requirements critical to the design are imposed by the weight, positional tolerance and assembly procedure of the MBS, and also, the magnetic field and vacuum dose rate of the DS bore. A detailed breakdown of how each requirement affects the structural design can be found in chapter 2. Chapter 3 describes the design of each support structure and its attachment to the MBS while chapter 4 describes the results from structural analysis of the support structures. Chapter 5 describes evaluation for the design through testing and calculations while the conclusion in chapter 6 reports the current status at the time of this thesis submission with a plan for future work to be completed until final design and installation.

  11. An Analysis of the New York City Police Department's "Stop-and-Frisk" Policy in the Context

    E-Print Network [OSTI]

    Gelman, Andrew

    An Analysis of the New York City Police Department's "Stop-and-Frisk" Policy in the Context analyze data from 125,000 pedestrian stops by the New York Police Department over a 15-month period. We rates, policy debates on polic- ing strategies often pivot on the evaluation of New York City's policing

  12. Evaluation of Stopping Powers of Superheavy Ions with $\\it{Z}$ up to 124 in Al and U

    E-Print Network [OSTI]

    Yong Hee Chung

    2015-02-01

    Electronic and nuclear stopping powers of superheavy ions with $\\it{Z}$ up to 124 and $\\it{A}$=300 in Al and U were estimated in the energy range of 0.01-0.20 MeV/u. The corresponding stopping powers were estimated using stopping powers of ions with 6$\\leq$$\\it{Z}$$\\leq$92 obtained from SRIM. The results were compared with those deduced from Northcliffe and Schilling$'$s stopping-power tables and with experimental data for $^{16}$O and $^{19}$F ions in Al. Estimated electronic stopping powers of the light ions agreed better with their experimental values above 0.10 MeV/u than the SRIM data.

  13. High resolution time interval meter

    DOE Patents [OSTI]

    Martin, A.D.

    1986-05-09

    Method and apparatus are provided for measuring the time interval between two events to a higher resolution than reliability available from conventional circuits and component. An internal clock pulse is provided at a frequency compatible with conventional component operating frequencies for reliable operation. Lumped constant delay circuits are provided for generating outputs at delay intervals corresponding to the desired high resolution. An initiation START pulse is input to generate first high resolution data. A termination STOP pulse is input to generate second high resolution data. Internal counters count at the low frequency internal clock pulse rate between the START and STOP pulses. The first and second high resolution data are logically combined to directly provide high resolution data to one counter and correct the count in the low resolution counter to obtain a high resolution time interval measurement.

  14. miR-421 induces cell proliferation and apoptosis resistance in human nasopharyngeal carcinoma via downregulation of FOXO4

    SciTech Connect (OSTI)

    Chen, Liang; Department of Otolaryngology, Guangzhou General Hospital of PLA Guangzhou Command, Guangzhou 510010 ; Tang, Yanping; Wang, Jian; Yan, Zhongjie; Xu, Ruxiang

    2013-06-14

    Highlights: •miR-421 is upregulated in nasopharyngeal carcinoma. •miR-421 induces cell proliferation and apoptosis resistance. •FOXO4 is a direct and functional target of miR-421. -- Abstract: microRNAs have been demonstrated to play important roles in cancer development and progression. Hence, identifying functional microRNAs and better understanding of the underlying molecular mechanisms would provide new clues for the development of targeted cancer therapies. Herein, we reported that a microRNA, miR-421 played an oncogenic role in nasopharyngeal carcinoma. Upregulation of miR-421 induced, whereas inhibition of miR-421 repressed cell proliferation and apoptosis resistance. Furthermore, we found that upregulation of miR-421 inhibited forkhead box protein O4 (FOXO4) signaling pathway following downregulation of p21, p27, Bim and FASL expression by directly targeting FOXO4 3?UTR. Additionally, we demonstrated that FOXO4 expression is critical for miR-421-induced cell growth and apoptosis resistance. Taken together, our findings not only suggest that miR-421 promotes nasopharyngeal carcinoma cell proliferation and anti-apoptosis, but also uncover a novel regulatory mechanism for inactivation of FOXO4 in nasopharyngeal carcinoma.

  15. Helical tomotherapy with dynamic running-start-stop delivery compared to conventional tomotherapy delivery

    SciTech Connect (OSTI)

    Rong, Yi, E-mail: yi.rong@osumc.edu [Department of Radiation Oncology, The Ohio State University Wexner Medical Center, Columbus, Ohio 43210 (United States)] [Department of Radiation Oncology, The Ohio State University Wexner Medical Center, Columbus, Ohio 43210 (United States); Chen, Yu; Lu, Weiguo [21st Century Oncology, Madison, Wisconsin 53719 (United States)] [21st Century Oncology, Madison, Wisconsin 53719 (United States); Shang, Lu [Guangxi Polytechnic of Construction and Technology, Nanning (China)] [Guangxi Polytechnic of Construction and Technology, Nanning (China); Zuo, Li [Radiologic Sciences and Respiratory Therapy Division, School of Health and Rehabilitation Sciences, The Ohio State University College of Medicine, Columbus, Ohio 43210 (United States)] [Radiologic Sciences and Respiratory Therapy Division, School of Health and Rehabilitation Sciences, The Ohio State University College of Medicine, Columbus, Ohio 43210 (United States); Chen, Quan [Department of Radiation Oncology, University of Virginia, Charlottesville, Virginia 22904 (United States)] [Department of Radiation Oncology, University of Virginia, Charlottesville, Virginia 22904 (United States)

    2014-05-15

    Purpose: Despite superior target dose uniformity, helical tomotherapy{sup ®} (HT) may involve a trade-off between longitudinal dose conformity and beam-on time (BOT), due to the limitation of only three available jaw sizes with the conventional HT (1.0, 2.5, and 5.0 cm). The recently introduced dynamic running-start-stop (RSS) delivery allows smaller jaw opening at the superior and inferior ends of the target when a sharp penumbra is needed. This study compared the dosimetric performance of RSS delivery with the fixed jaw HT delivery. Methods: Twenty patient cases were selected and deidentified prior to treatment planning, including 16 common clinical cases (brain, head and neck (HN), lung, and prostate) and four special cases of whole brain with hippocampus avoidance (WBHA) that require a high degree of dose modulation. HT plans were generated for common clinical cases using the fixed 2.5 cm jaw width (HT2.5) and WBHA cases using 1.0 cm (HT1.0). The jaw widths for RSS were preset with a larger size (RSS5.0 vs HT2.5 and RSS2.5 vs HT1.0). Both delivery techniques were planned based on identical contours, prescriptions, and planning objectives. Dose indices for targets and critical organs were compared using dose-volume histograms, BOT, and monitor units. Results: The average BOT was reduced from 4.8 min with HT2.5 to 2.5 min with RSS5.0. Target dose homogeneity with RSS5.0 was shown comparable to HT2.5 for common clinical sites. Superior normal tissue sparing was observed in RSS5.0 for optic nerves and optic chiasm in brain and HN cases. RSS5.0 demonstrated improved dose sparing for cord and esophagus in lung cases, as well as penile bulb in prostate cases. The mean body dose was comparable for both techniques. For the WBHA cases, the target homogeneity was significantly degraded in RSS2.5 without distinct dose sparing for hippocampus, compared to HT1.0. Conclusions: Compared to the fixed jaw HT delivery, RSS combined with a larger jaw width provides faster treatment delivery and improved cranial-caudal target dose conformity. The target coverage achieved by RSS with a large jaw width is comparable to the fixed jaw HT delivery for common cancer sites, but may deteriorate for cases where complex geometry is present in the middle part of the target.

  16. Single-molecule modeling of mRNA degradation by miRNA: Lessons from data

    E-Print Network [OSTI]

    Celine Sin; Davide Chiarugi; Angelo Valleriani

    2014-10-20

    Recent experimental results on the effect of miRNA on the decay of its target mRNA have been analyzed against a previously hypothesized single molecule degradation pathway. According to that hypothesis, the silencing complex (miRISC) first interacts with its target mRNA and then recruits the protein complexes associated with NOT1 and PAN3 to trigger deadenylation (and subsequent degradation) of the target mRNA. Our analysis of the experimental decay patterns allowed us to refine the structure of the degradation pathways at the single molecule level. Surprisingly, we found that if the previously hypothesized network was correct, only about 7% of the target mRNA would be regulated by the miRNA mechanism, which is inconsistent with the available knowledge. Based on systematic data analysis, we propose the alternative hypothesis that NOT1 interacts with miRISC before binding to the target mRNA. Moreover, we show that when miRISC binds alone to the target mRNA, the mRNA is degraded more slowly, probably through a deadenylation-independent pathway. The new biochemical pathway we propose both fits the data and paves the way for new experimental work to identify new interactions.

  17. Measurement of charged-particle stopping in warm-dense plasma

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Zylstra, A.? B. [MIT (Massachusetts Inst. of Technology), Cambridge, MA (United States); Frenje, J.? A. [MIT (Massachusetts Inst. of Technology), Cambridge, MA (United States); Grabowski, P. E. [Univ. of California Irvine, Irvine, CA (United States); Li, C. ?K. [MIT (Massachusetts Inst. of Technology), Cambridge, MA (United States); Collins, G.? W. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Fitzsimmons, P. [General Atomics, San Diego, CA (United States); Glenzer, S. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Graziani, F. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Hansen, S.? B. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Hu, S. X. [Univ. of Rochester, NY (United States); Johnson, M. Gatu [MIT (Massachusetts Inst. of Technology), Cambridge, MA (United States); Keiter, P. [Univ. of Michigan, Ann Arbor, MI (United States); Reynolds, H. [General Atomics, San Diego, CA (United States); Rygg, J.? R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Séguin, F. H. [MIT (Massachusetts Inst. of Technology), Cambridge, MA (United States); Petrasso, R. D. [MIT (Massachusetts Inst. of Technology), Cambridge, MA (United States)

    2015-05-01

    We measured the stopping of energetic protons in an isochorically-heated solid-density Be plasma with an electron temperature of ~32 eV, corresponding to moderately-coupled [(e²/a/(kBTe + EF ) ~ 0.3] and moderately-degenerate [kBTe/EF ~2] 'warm dense matter' (WDM) conditions. We present the first high-accuracy measurements of charged-particle energy loss through dense plasma, which shows an increased loss relative to cold matter, consistent with a reduced mean ionization potential. The data agree with stopping models based on an ad-hoc treatment of free and bound electrons, as well as the average-atom local-density approximation; this work is the first test of these theories in WDM plasma.

  18. Measurement of charged-particle stopping in warm-dense plasma

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Zylstra, A.? B.; Frenje, J.? A.; Grabowski, P. E.; Li, C. ?K.; Collins, G.? W.; Fitzsimmons, P.; Glenzer, S.; Graziani, F.; Hansen, S.? B.; Hu, S. X.; et al

    2015-05-27

    We measured the stopping of energetic protons in an isochorically-heated solid-density Be plasma with an electron temperature of ~32 eV, corresponding to moderately-coupled [(e²/a/(kBTe + EF ) ~ 0.3] and moderately-degenerate [kBTe/EF ~2] 'warm dense matter' (WDM) conditions. We present the first high-accuracy measurements of charged-particle energy loss through dense plasma, which shows an increased loss relative to cold matter, consistent with a reduced mean ionization potential. The data agree with stopping models based on an ad-hoc treatment of free and bound electrons, as well as the average-atom local-density approximation; this work is the first test of these theories inmore »WDM plasma.« less

  19. Measurement of charged-particle stopping in warm-dense plasma

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Zylstra, A. B.; Frenje, J. A.; Grabowski, P.? E.; Li, C.? K.; Collins, G.? W.; Fitzsimmons, P.; Glenzer, S.; Graziani, F.; Hansen, S.? B.; Hu, S.? X.; et al

    2015-05-01

    We measured the stopping of energetic protons in an isochorically-heated solid-density Be plasma with an electron temperature of ~32 eV , corresponding to moderately-coupled [(e²/a)/(kBTe + EF ) ~ 0.3] and moderately degenerate [kBTe/EF ~2] 'warm-dense matter' (WDM) conditions. We present the first high-accuracy measurements of charged-particle energy loss through dense plasma, which shows an increased loss relative to cold matter, consistent with a reduced mean ionization potential. The data agree with stopping models based on an ad-hoc treatment of free and bound electrons, as well as the average-atom local-density approximation; this work is the first test of these theoriesmore »in WDM plasma.« less

  20. Theoretical studies on the stopping power of deuterium-tritium mixed with uranium plasmas for ? particles

    SciTech Connect (OSTI)

    Wang, Zhigang; Fu, Zhen-Guo; Zhang, Ping

    2014-10-15

    The stopping power of a compressed and highly ionized deuterium-tritium (DT) and uranium (U) plasma for ? particles at very high temperatures (T?=?5?keV) is examined theoretically with the dimensional continuation method. We show that with increasing density of U, both the magnitude and width of the resonance peak in the stopping power (as a function of the ? particle energy), increases because of the ions, while the penetration distance of the ? particles decreases. A simple relation of decreasing penetration distance as a function of plasma density is observed, which may be useful for inertial confinement fusion experiments. Moreover, by comparing the results with the case of a DT plasma mixed with beryllium, we find that the effect of a higher Z plasma is stronger, with regard to energy loss as well as the penetration distance of ? particles, than that of a lower Z plasma.

  1. Topeka’s “Green Light Tunnel” Saves Fuel and Time

    Broader source: Energy.gov [DOE]

    Topeka, Kansas is saving their motorists time and gasoline through the use of a real-time, adaptive "green light tunnel". A traffic signal system that synchronizes traffic lights in order to create a series of green lights that result in fewer stops and less travel time.

  2. AVTA: Quantifying the Effects of Idle Stop Systems on Fuel Economy

    Office of Energy Efficiency and Renewable Energy (EERE)

    The Vehicle Technologies Office's Advanced Vehicle Testing Activity carries out testing on a wide range of advanced vehicles and technologies on dynamometers, closed test tracks, and on-the-road. These results provide benchmark data that researchers can use to develop technology models and guide future research and development. This report gives an overall analysis of stop-start technology. This research was conducted by Idaho National Laboratory.

  3. Comparing EFT and Exact One-Loop Analyses of Non-Degenerate Stops

    E-Print Network [OSTI]

    Aleksandra Drozd; John Ellis; Jeremie Quevillon; Tevong You

    2015-04-09

    We develop a universal approach to the one-loop effective field theory (EFT) using the Covariant Derivative Expansion (CDE) method. We generalise previous results to include broader classes of UV models, showing how expressions previously obtained assuming degenerate heavy-particle masses can be extended to non-degenerate cases. We apply our method to the general MSSM with non-degenerate stop squarks, illustrating our approach with calculations of the coefficients of dimension-6 operators contributing to the $hgg$ and $h\\gamma\\gamma$ couplings, and comparing with exact calculations of one-loop Feynman diagrams. We then use present and projected future sensitivities to these operator coefficients to obtain present and possible future indirect constraints on stop masses. The current sensitivity is already comparable to that of direct LHC searches, and future FCC-ee measurements could be sensitive to stop masses above a TeV. The universality of our one-loop EFT approach facilitates extending these constraints to a broader class of UV models.

  4. Reaction-in-Flight Neutrons as a Test of Stopping Power in Degenerate Plasmas

    E-Print Network [OSTI]

    A. C. Hayes; Gerard Jungman; A. E. Schulz; M. Boswell; M. M. Fowler; G. Grim; A. Klein; R. S. Rundberg; J. B. Wilhelmy; D. Wilson

    2014-11-25

    We present the first measurements of reaction-in-flight (RIF) neutrons in an inertial confinement fusion system. The experiments were carried out at the National Ignition Facility, using both Low Foot and High Foot drives and cryogenic plastic capsules. In both cases, the high-energy RIF ($E_n>$ 15 MeV) component of the neutron spectrum was found to be about $10^{-4}$ of the total. The majority of the RIF neutrons were produced in the dense cold fuel surrounding the burning hotspot of the capsule and the data are consistent with a compressed cold fuel that is moderately to strongly coupled $(\\Gamma\\sim$0.6) and electron degenerate $(\\theta_\\mathrm{Fermi}/\\theta_e\\sim$4). The production of RIF neutrons is controlled by the stopping power in the plasma. Thus, the current RIF measurements provide a unique test of stopping power models in an experimentally unexplored plasma regime. We find that the measured RIF data strongly constrain stopping models in warm dense plasma conditions and some models are ruled out by our analysis of these experiments.

  5. Stopping power for a charged particle moving through three-dimensional nonideal finite-temperature electron gases

    SciTech Connect (OSTI)

    Zhang Ya; Song Yuanhong; Wang Younian [School of Physics and Optoelectronic Technology, Dalian University of Technology, Dalian 116024 (China)

    2011-07-15

    We investigate the interaction of a charged particle with nonideal 3D electron gases by using the quantum hydrodynamic (QHD) theory. The stopping power for a nonideal electron gas at a finite-temperature has been theoretically analyzed and numerically calculated. In our calculation, the impact of nonideality and temperature on stopping power is stressed and clearly presented. The QHD dielectric function is obtained and compared to random-phase approximation result. It is shown that the QHD theory can properly describe the stopping power for higher particle velocities greater than the Bohr velocity.

  6. Dose calculations using MARS for Bremsstrahlung beam stops and collimators in APS beamline stations.

    SciTech Connect (OSTI)

    Dooling, J.; Accelerator Systems Division

    2010-11-01

    The Monte Carlo radiation transport code MARS is used to model the generation of gas bremsstrahlung (GB) radiation from 7-GeV electrons which scatter from residual gas atoms in undulator straight sections within the Advanced Photon Source (APS) storage ring. Additionally, MARS is employed to model the interactions of the GB radiation with components along the x-ray beamlines and then determine the expected radiation dose-rates that result. In this manner, MARS can be used to assess the adequacy of existing shielding or the specifications for new shielding when required. The GB radiation generated in the 'thin-target' of an ID straight section will consist only of photons in a 1/E-distribution up to the full energy of the stored electron beam. Using this analytical model, the predicted GB power for a typical APS 15.38-m insertion device (ID) straight section is 4.59 x 10{sup -7} W/nTorr/mA, assuming a background gas composed of air (Z{sub eff} = 7.31) at room temperature (293K). The total GB power provides a useful benchmark for comparisons between analytical and numerical approaches. We find good agreement between MARS and analytical estimates for total GB power. The extended straight section 'target' creates a radial profile of GB, which is highly peaked centered on the electron beam. The GB distribution reflects the size of the electron beam that creates the radiation. Optimizing the performance of MARS in terms of CPU time per incident trajectory requires the use of a relatively short, high-density gas target (air); in this report, the target density is {rho}L = 2.89 x 10{sup -2} g/cm{sup 2} over a length of 24 cm. MARS results are compared with the contact dose levels reported in TB-20, which used EGS4 for radiation transport simulations. Maximum dose-rates in 1 cc of tissue phantom form the initial basis for comparison. MARS and EGS4 results are approximately the same for maximum 1-cc dose-rates and attenuation in the photon-dominated regions; for thicker targets, however, the dose-rate no longer depends only on photon attenuation, as photoneutrons (PNs) begin to dominate. The GB radiation-induced photoneutron measurements from four different metals (Fe, Cu, W, and Pb) are compared with MARS predictions. The simulated dose-rates for beamline 6-ID are approximately 3-5 times larger than the measured values, whereas those for beamline 11-ID are much closer. Given the uncertainty in local values of pressure and Z, the degree of agreement between MARS and the PN measurements is good. MARS simulations of GB-induced radiation in and around the FOE show the importance of using actual pressure and gas composition (Z{sub eff}) to obtain accurate PN dose. For a beam current of 300 mA, extrapolating pressure data measured in previously published studies predicts an average background gas pressure of 27 nTorr. An average atomic number of Z{sub eff} = 4.0 is obtained from the same studies. In addition, models of copper masks presently in use at the APS are included. Simulations show that inclusion of exit masks make significant differences in both the radiation spatial distribution within the FOE, as well as the peak intensity. Two studies have been conducted with MARS to assess shielding requirements. First, dose levels in contact with the outside wall of the FOE are examined when GB radiation strikes Pb or W beam stops of varying transverse size within the FOE. Four separate phantom regions are utilized to measure the dose, two at beam elevation and two at the horizontal beam position. The first two phantoms are used for scoring FOE dose along the outside and back walls, horizontally; the second two collect dose on the roof and vertically on the back wall. In all cases, the beam stop depth is maintained at 30 cm. Inclusion of front end (FE) exit masks typically cause a 1-2 order-of-magnitude increase in the dose-rates relative to the case with no masks. Masks place secondary bremsstrahlung sources inside the FOE, and therefore they must be shielded appropriately. The MARS model does not fully account for all shielding present

  7. Search for decays of stopped long-lived particles produced in proton-proton collisions at sqrt(s) = 8 TeV

    E-Print Network [OSTI]

    CMS Collaboration

    2015-04-14

    A search has been performed for long-lived particles that could have come to rest within the CMS detector, using the time intervals between LHC beam crossings. The existence of such particles could be deduced from observation of their decays via energy deposits in the CMS calorimeter appearing at times that are well separated from any proton-proton collisions. Using a data set corresponding to an integrated luminosity of 18.6 inverse femtobarns of 8 TeV proton-proton collisions, and a search interval corresponding to 281 hours of trigger livetime, 10 events are observed, with a background prediction of 13.2 +3.6 -2.5 events. Limits are presented at 95% confidence level on gluino and top squark production, for over 13 orders of magnitude in the mean proper lifetime of the stopped particle. Assuming a cloud model of R-hadron interactions, a gluino with mass < 1000 GeV and a top squark with mass < 525 GeV are excluded, for lifetimes between 1 microsecond and 1000 s. These results are the most stringent constraints on stopped particles to date.

  8. Search for decays of stopped long-lived particles produced in proton–proton collisions at ?s = 8 TeV

    SciTech Connect (OSTI)

    Khachatryan, V.

    2015-04-11

    A search has been performed for long-lived particles that could have come to rest within the CMS detector, using the time intervals between LHC beam crossings. The existence of such particles could be deduced from observation of their decays via energy deposits in the CMS calorimeter appearing at times that are well separated from any proton–proton collisions. Using a data set corresponding to an integrated luminosity of 18.6fb?¹ of 8TeV proton–proton collisions, and a search interval corresponding to 281 h of trigger livetime, 10 events are observed, with a background prediction of 13.2+3.6–2.5 events. Limits are presented at 95 % confidence level on gluino and top squark production, for over 13 orders of magnitude in the mean proper lifetime of the stopped particle. Assuming a cloud model of R-hadron interactions, a gluino with mass ?1000GeV and a top squark with mass ?525GeV are excluded, for lifetimes between 1 ?s and 1000s. These results are the most stringent constraints on stopped particles to date.

  9. Search for decays of stopped long-lived particles produced in proton–proton collisions at ?s = 8 TeV

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Khachatryan, V.

    2015-04-11

    A search has been performed for long-lived particles that could have come to rest within the CMS detector, using the time intervals between LHC beam crossings. The existence of such particles could be deduced from observation of their decays via energy deposits in the CMS calorimeter appearing at times that are well separated from any proton–proton collisions. Using a data set corresponding to an integrated luminosity of 18.6fb?¹ of 8TeV proton–proton collisions, and a search interval corresponding to 281 h of trigger livetime, 10 events are observed, with a background prediction of 13.2+3.6–2.5 events. Limits are presented at 95 %more »confidence level on gluino and top squark production, for over 13 orders of magnitude in the mean proper lifetime of the stopped particle. Assuming a cloud model of R-hadron interactions, a gluino with mass ?1000GeV and a top squark with mass ?525GeV are excluded, for lifetimes between 1 ?s and 1000s. These results are the most stringent constraints on stopped particles to date.« less

  10. Ion-lithium collision dynamics studied with an in-ring MOTReMi

    E-Print Network [OSTI]

    Fischer, D; Goullon, J; Grieser, M; Hubele, R; de Jesus, V L B; Kelkar, A; LaForge, A; Lindenblatt, H; Misra, D; Najjari, B; Schneider, K; Schulz, M; Sell, M; Wang, X

    2012-01-01

    We present a novel experimental tool allowing for kinematically complete studies of break-up processes of laser-cooled atoms. This apparatus, the 'MOTReMi', is a combination of a magneto-optical trap (MOT) and a Reaction Microscope (ReMi). Operated in an ion-storage ring, the new setup enables to study the dynamics in swift ion-atom collisions on an unprecedented level of precision and detail. In first experiments on collisions with 1.5 MeV/amu O$^{8+}$-Li the pure ionization of the valence electron as well as ionization-excitation of the lithium target has been investigated.

  11. Role of <mi>Ce>4+ in the scintillation mechanism of codoped <mi>Gd>3<mi>Ga>3<mi>Al>2<mi mathvariant='normal'>Omi>12:<mi>Ce>

    SciTech Connect (OSTI)

    Wu, Yuntao; Meng, Fang; Li, Qi; Koschan, Merry; Melcher, Charles L.

    2014-10-17

    To control the time-response performance of widely used cerium-activated scintillators in cutting-edge medical-imaging devices, such as time-of-flight positron-emission tomography, a comprehensive understanding of the role of Ce valence states, especially stable Ce4+, in the scintillation mechanism is essential. However, despite some progress made recently, an understanding of the physical processes involving Ce4+ is still lacking. The aim of this work is to clarify the role of Ce4+ in scintillators by studying Ca2+ codoped Gd3Ga3Al2O12?Ce?(GGAG?Ce). By using a combination of optical absorption spectra and x-ray absorption near-edge spectroscopies, the correlation between Ca2+codoping content and the Ce4+ fraction is seen. The energy-level diagrams of Ce3+ and Ce4+ in the Gd3Ga3Al2O12 host are established by using theoretical and experimental methods, which indicate a higher position of the 5d1 state of Ce4+ in the forbidden gap in comparison to that of Ce3+. Underlying reasons for the decay-time acceleration resulting from Ca2+ codoping are revealed, and the physical processes of the Ce4+-emission model are proposed and further demonstrated by temperature-dependent radioluminescence spectra under x-ray excitation.

  12. Company City State Contact Info 21st Century Plastics Corporation Potterville MI www.21stcpc.com

    E-Print Network [OSTI]

    McGaughey, Alan

    Engineered Plastics, LLC Auburn Hills MI www.deltaengineeredplastics.com Detrex Corporation.dutchlandplastics.com E & O Tool & Plastics, Inc. Elk River MN www.eoplastics.com E & T Plastic Rubber & Plastics Corp. Farmington Hills MI www.exoticautomation.com F & D Plastics, Inc

  13. Innovating with institutions : how strategic orientations among one-stop career centers influence labor matching, adaptation, and performance

    E-Print Network [OSTI]

    Herranz, Joaquin

    2004-01-01

    Set in the context of labor market restructuring, public policy reform, and blurring government/nonprofit boundaries, this study examines the functions, adaptation, and performance of Boston's three One-Stop Career Centers ...

  14. Design-led approach for transferring the embodied skills of puppet stop-motion animators into haptic workspaces 

    E-Print Network [OSTI]

    Dima, Maria

    2013-06-28

    This design-led research investigates the transfer of puppet stop-motion animators’ embodied skills from the physical workspace into a digital environment. The approach is to create a digital workspace that evokes an ...

  15. Roles of the MicroRNA miR-31 in tumor metastasis and an experimental system for the unbiased discovery of genes relevant for breast cancer metastasis

    E-Print Network [OSTI]

    Valastyan, Scott J. (Scott John)

    2010-01-01

    In these studies, the microRNA miR-31 was identified as a potent inhibitor of breast cancer metastasis. miR-31 expression levels were inversely associated with the propensity to develop metastatic disease in human breast ...

  16. Quantifying the Effects of Idle-Stop Systems on Fuel Economy in Light-Duty Passenger Vehicles

    SciTech Connect (OSTI)

    Jeff Wishart; Matthew Shirk

    2012-12-01

    Vehicles equipped with idle-stop (IS) systems are capable of engine shut down when the vehicle is stopped and rapid engine re-start for the vehicle launch. This capability reduces fuel consumption and emissions during periods when the engine is not being utilized to provide propulsion or to power accessories. IS systems are a low-cost and fast-growing technology in the industry-wide pursuit of increased vehicle efficiency, possibly becoming standard features in European vehicles in the near future. In contrast, currently there are only three non-hybrid vehicle models for sale in North America with IS systems and these models are distinctly low-volume models. As part of the United States Department of Energy’s Advanced Vehicle Testing Activity, ECOtality North America has tested the real-world effect of IS systems on fuel consumption in three vehicle models imported from Europe. These vehicles were chosen to represent three types of systems: (1) spark ignition with 12-V belt alternator starter; (2) compression ignition with 12-V belt alternator starter; and (3) direct-injection spark ignition, with 12-V belt alternator starter/combustion restart. The vehicles have undergone both dynamometer and on-road testing; the test results show somewhat conflicting data. The laboratory data and the portion of the on-road data in which driving is conducted on a prescribed route with trained drivers produced significant fuel economy improvement. However, the fleet data do not corroborate improvement, even though the data show significant engine-off time. It is possible that the effects of the varying driving styles and routes in the fleet testing overshadowed the fuel economy improvements. More testing with the same driver over routes that are similar with the IS system-enabled and disabled is recommended. There is anecdotal evidence that current Environmental Protection Agency fuel economy test procedures do not capture the fuel economy gains that IS systems produce in real-world driving. The program test results provide information on the veracity of these claims.

  17. Reprinted from the Proceedings of the 1998 ASEE North Central Section Meeting, University of Detroit Mercy, Detroit, MI, April 3-4, 1998. ( Best Paper Award )

    E-Print Network [OSTI]

    Bell, John T.

    of Detroit Mercy, Detroit, MI, April 3-4, 1998. ( Best Paper Award ) VIRTUAL REALITY IN CHEMICAL ENGINEERING

  18. Robustness of the Baryon-Stopping Signal for the Onset of Deconfinement in Relativistic Heavy-Ion Collisions

    E-Print Network [OSTI]

    Yu. B. Ivanov; D. Blaschke

    2015-05-28

    The impact of the experimental acceptance, i.e. transverse-momentum ($p_T$) cut-off and limited rapidity region, on the earlier predicted irregularity in the excitation function of the baryon stopping is studied. This irregularity is a consequence of the onset of deconfinement occurring in the compression stage of a nuclear collision and manifests itself as a wiggle in the excitation function of the reduced curvature ($C_y$) of the net-proton rapidity distribution at midrapidity. It is demonstrated that the wiggle is a very robust signal of a first-order phase transition that survives even under conditions of a very limited acceptance. At the same time the $C_y$ for pure hadronic and crossover transition scenarios become hardly distinguishable, if the acceptance cuts off too much of the low-$p_T$ proton spectrum and/or puts too narrow rapidity window around midrapidity. It is found that the shape of the net-proton rapidity distribution near midrapidity depends on the $p_T$ cut-off. This implies that the measurements should be taken at the same acceptance for all collision energies in order to reliably conclude on the presence or absence of the irregularity.

  19. Robustness of the Baryon-Stopping Signal for the Onset of Deconfinement in Relativistic Heavy-Ion Collisions

    E-Print Network [OSTI]

    Ivanov, Yu B

    2015-01-01

    The impact of the experimental acceptance, i.e. transverse-momentum ($p_T$) cut-off and limited rapidity region, on the earlier predicted irregularity in the excitation function of the baryon stopping is studied. This irregularity is a consequence of the onset of deconfinement occurring in the compression stage of a nuclear collision and manifests itself as a wiggle in the excitation function of the reduced curvature ($C_y$) of the net-proton rapidity distribution at midrapidity. It is demonstrated that the wiggle is a very robust signal of a first-order phase transition that survives even under conditions of a very limited acceptance. At the same time the $C_y$ for pure hadronic and crossover transition scenarios become hardly distinguishable, if the acceptance cuts off too much of the low-$p_T$ proton spectrum and/or puts too narrow rapidity window around midrapidity. It is found that the shape of the net-proton rapidity distribution near midrapidity depends on the $p_T$ cut-off. This implies that the measu...

  20. Self-induced transparency, compression, and stopping of electromagnetic pulses interacting with beams of unexcited classical oscillators

    SciTech Connect (OSTI)

    Ginzburg, N. S.; Zotova, I. V., E-mail: zotova@appl.sci-nnov.ru; Sergeev, A. S. [Russian Academy of Sciences, Institute of Applied Physics (Russian Federation)

    2011-11-15

    The self-induced transparency effects that emerge when short (on the relaxation time scale) light pulses propagate in a two-level noninverted medium are well known in optics. The interaction of microwave pulses with an initially rectilinear electron beam under cyclotron resonance conditions can serve as a classical analog of the described effects. In this case, at a certain intensity of the input signal, the cyclotron absorption is replaced by self-induced transparency when the input pulse propagates almost without any change of its profile, forming a soliton whose amplitude and duration are rigidly related to its velocity. In a certain domain of parameters, this process is accompanied by significant two- or threefold compression of the initial pulse, which is of practical interest for the generation of multigigawatt picosecond microwave pulses. Since the soliton velocity lies between the unperturbed group velocity of the radiation and the translational velocity of the particles, another nontrivial effect in the case of interaction with a counterpropagating electron beam is the possibility of a significant deceleration or full stopping of the electromagnetic pulse.

  1. BENDIX SYSTEMS DIVISION ANN AIt 1 o I, MI CH NO. Plan for Operational Contingency

    E-Print Network [OSTI]

    Rathbun, Julie A.

    8/29/66 BENDIX SYSTEMS DIVISION ANN AIt 1 o I, MI CH NO. ATM-396 Plan for Operational Contingency of the operational plans and the system design and to study methods of recovery from partial failure through the use. ATM- 396 RIV.MO. A I I f..r I (I IOperational Contingency Study 2 PAGI OP

  2. New Loops! MiTeGen* 50MicroMountsTM consist of a thin microfabricated

    E-Print Network [OSTI]

    Meagher, Mary

    New Loops! MiTeGen* 50µMicroMountsTM consist of a thin microfabricated polyimide film attached to a solid non-magnetic stainless steel pin. The film is polyimide, which is used in Kapton® tape and is employed for X- ray transparent windows on X-ray beam lines. The film is curved by wrapping polyimide film

  3. 2000 JAPAN-USA Symposium on Flexible Automation July 23-26, 2000, Ann Arbor, MI

    E-Print Network [OSTI]

    Saitou, Kazuhiro "Kazu"

    2000 JAPAN-USA Symposium on Flexible Automation July 23-26, 2000, Ann Arbor, MI 2000JUSFA-US1 OFF-LINE ERROR RECOVERY LOGIC SYNTHESIS IN AUTOMATED ASSEMBLY LINES BY USING GENETIC PROGRAMMING Cem M. Baydar by the experts or automated error recovery logic controllers embedded in the system. The previous work

  4. An HNF4a-miRNA Inflammatory Feedback Circuit Regulates

    E-Print Network [OSTI]

    An HNF4a-miRNA Inflammatory Feedback Circuit Regulates Hepatocellular Oncogenesis Maria, once this circuit is activated, it maintains suppression of HNF4a and sustains oncogenesis. Systemic recapitulate hepatic oncogenesis in various animal models (He et al., 2010). In addition, the inflammatory

  5. AUSTRALIAN. N~TIONAL UNIVE~SITY DEPARTMENTO:miNUCLEAR PFf-y'SICS

    E-Print Network [OSTI]

    Chen, Ying

    AUSTRALIAN. N~TIONAL UNIVE~SITY DEPARTMENTO:miNUCLEAR PFf-y'SICS 14UD TANK OPENING REPORT/iNo. 51 functions for which it provides power. An order was . immediately placed with N.E.C. for 28 perspex bars microamp hours of b.d.p. generation than its predicted lifetime. In preparation for the next opening

  6. MSU CENTER FOR REGIONAL FOOD SYSTEMS 480 WILSON ROAD, EAST LANSING, MI 48824

    E-Print Network [OSTI]

    AN ANNOTATED BIBLIOGRAPHY ON STRUCTURAL RACISM PRESENT IN THE U.S. FOOD SYSTEM JUNE 2015 #12;Michigan State University Center for Regional Food Systems Structural Racism Present in the U.S. Food System 2 AUTHORS Anel on structural racism present in the U.S. food system. East Lansing, MI: MSU Center for Regional Food Systems

  7. Request for Alternative Activity for PLI Credit Last Name First Name M.I.

    E-Print Network [OSTI]

    Connors, Daniel A.

    Request for Alternative Activity for PLI Credit Full Name: Last Name First Name M.I. Email Address information for Coordinator of Program: Requesting Alternate Activity credit for which PLI Track (Choose one): Verification Information Email Address: College of Engineering Student Information Alternate Activity

  8. MI FARM TO SCHOOL GRANTEES 2014-2015 PROGRAM YEAR AND PREVIOUS GRANTEES

    E-Print Network [OSTI]

    MI FARM TO SCHOOL GRANTEES 2014-2015 PROGRAM YEAR AND PREVIOUS GRANTEES FOODSYSTEMS.MSU.EDU 2014-2015 GRANTEES School/ district/ program County Current Grant Years as a grantee A&W Daycare Wayne Planning 1 TO SCHOOL GRANTEES (2011/12 ­ 2013/14) School/ district/ program County Grant Type(s) Grant Years All Aboard

  9. Polyphenol-induced Anti-inflammatory and Cytotoxic Activities in Breast and Colon Cancer: Potential Role of miRNA's in Cell Survival and Inflammation 

    E-Print Network [OSTI]

    Banerjee, Nivedita

    2013-12-11

    growth in athymic BALB/c nude mice with BT474 xenografts. Interactions of Pg with miR-27a- ZBTB10-Sp and miR-155-SHIP-1-PI3K axes and mango miR126/PI3K/AKT axis were identified. In addition, pomegranate and plum polyphenols exerted cytotoxic and anti...

  10. SAE 1983 Transactions, Paper No. 830200, pp. 1.810-1.816 International Congress & Exposition, Detroit, Mi., Feb. 28-March 4, 1983

    E-Print Network [OSTI]

    Radcliffe, Clark J.

    , Detroit, Mi., Feb. 28- March 4, 1983 #12;SAE 1983 Transactions, Paper No. 830200, pp. 1.810-1.816 International Congress & Exposition, Detroit, Mi., Feb. 28- March 4, 1983 #12;SAE 1983 Transactions, Paper No. 830200, pp. 1.810-1.816 International Congress & Exposition, Detroit, Mi., Feb. 28- March 4, 1983 Fig. 2

  11. MiR-18a regulates the proliferation, migration and invasion of human glioblastoma cell by targeting neogenin

    SciTech Connect (OSTI)

    Song, Yichen; Wang, Ping; Zhao, Wei; Yao, Yilong; Liu, Xiaobai; Ma, Jun; Xue, Yixue; Liu, Yunhui

    2014-05-15

    MiR-17-92 cluster has recently been reported as an oncogene in some tumors. However, the association of miR-18a, an important member of this cluster, with glioblastoma remains unknown. Therefore, this study aims to investigate the expression of miR-18a in glioblastoma and its role in biological behavior of U87 and U251 human glioblastoma cell lines. Quantitative RT-PCR results showed that miR-18a was highly expressed in glioblastoma tissues and U87 and U251 cell lines compared with that in human brain tissues and primary normal human astrocytes, and the expression levels were increased along with the rising pathological grades of glioblastoma. Neogenin was identified as the target gene of miR-18a by dual-luciferase reporter assays. RT-PCR and western blot results showed that its expression levels were decreased along with the rising pathological grades of glioblastoma. Inhibition of miR-18a expression was established by transfecting exogenous miR-18a inhibitor into U87 and U251 cells, and its effects on the biological behavior of glioblastoma cells were studied using CCK-8 assay, transwell assay and flow cytometry. Inhibition of miR-18a expression in U87 and U251 cells significantly up-regulated neogenin, and dramatically suppressed the abilities of cell proliferation, migration and invasion, induced cell cycle arrest and promoted cellular apoptosis. Collectively, these results suggest that miR-18a may regulate biological behavior of human glioblastoma cells by targeting neogenin, and miR-18a can serve as a potential target in the treatment of glioblastoma. - Highlights: • MiR-18a was highly expressed in glioblastoma tissues and U87 and U251 cell lines. • Neogenin was identified as the target gene of miR-18a. • Neogenin expressions were decreased along with the rising pathological grades of glioblastoma. • Inhibition of miR-18a suppressed biological behavior of glioma cells by up-regulating neogenin.

  12. A study of stopping power in nuclear reactions at intermediate energies

    E-Print Network [OSTI]

    Lehaut, G; Lopez, O

    2010-01-01

    We show a systematic experimental study based on INDRA data of the stopping power in central symmetric nuclear reactions. Total mass of the systems goes from 80 to 400 nucleons while the incident energy range is from 12 AMeV to 100 AMeV. The role of isospin diffusion at 32 and 45 MeV/nucleon with 124,136Xe projectiles on 112,124Sn targets performed at GANIL is also discussed. Results suggest a strong memory of the entrance channel above 20 AMeV/A (nuclear transparency) and, as such, constitute valuable tests of the microscopic transport models.

  13. A study of stopping power in nuclear reactions at intermediate energies

    E-Print Network [OSTI]

    G. Lehaut; D. Durand; O. Lopez

    2010-01-25

    We show a systematic experimental study based on INDRA data of the stopping power in central symmetric nuclear reactions. Total mass of the systems goes from 80 to 400 nucleons while the incident energy range is from 12 AMeV to 100 AMeV. The role of isospin diffusion at 32 and 45 MeV/nucleon with 124,136Xe projectiles on 112,124Sn targets performed at GANIL is also discussed. Results suggest a strong memory of the entrance channel above 20 AMeV/A (nuclear transparency) and, as such, constitute valuable tests of the microscopic transport models.

  14. HIV/AIDS Information Resources from the National Library of Medicine-STOP

    SciTech Connect (OSTI)

    Templin-Branner, W. and N. Dancy

    2010-06-15

    The HIV/AIDS Information Resources from the National Library of Medicine training is designed specifically for the UNCFSP HBCU Screening, Testing, Outreach, and Prevention (STOP) HIV/AIDS Program project members to provide valuable health information resources from the National Library of Medicine and other reliable sources to increase awareness of the wealth of treatment information and educational materials that are available on the Internet and to improve prevention and treatment education for their clients. These resources will also meet the needs of community-based organizations

  15. Stop Paying for Energy You Aren't Using | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious RankADVANCED MANUFACTURINGEnergyPlan | Department of Energy 1 DOE| DepartmentHigh ImpactStop Paying for

  16. Freezing a Droplet to Stop the Ice | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverse (Journal Article)Forthcoming Upgrades toFreezing a Droplet to Stop the Ice

  17. miR-7 and miR-218 epigenetically control tumor suppressor genes RASSF1A and Claudin-6 by targeting HoxB3 in breast cancer

    SciTech Connect (OSTI)

    Li, Qiaoyan; Zhu, Fufan; Chen, Puxiang

    2012-07-20

    Highlights: Black-Right-Pointing-Pointer Both miR-7 and miR-218 down-regulates HoxB3 expression by targeting the 3 Prime -UTR of HoxB3 mRNA. Black-Right-Pointing-Pointer A reverse correlation between the levels of endogenous miR-7, miR218 and HoxB3 expression. Black-Right-Pointing-Pointer Epigenetic changes involve in the reactivation of HoxB3. Black-Right-Pointing-Pointer Both miRNAs inhibits the cell cycle and clone formation of breast cancer cells. -- Abstract: Many microRNAs have been implicated as key regulators of cellular growth and differentiation and have been found to dysregulate proliferation in human tumors, including breast cancer. Cancer-linked microRNAs also alter the epigenetic landscape by way of DNA methylation and post-translational modifications of histones. Aberrations in Hox gene expression are important for oncogene or tumor suppressor during abnormal development and malignancy. Although recent studies suggest that HoxB3 is critical in breast cancer, the putative role(s) of microRNAs impinging on HoxB3 is not yet fully understood. In this study, we found that the expression levels of miR-7 and miR-218 were strongly and reversely associated with HoxB3 expression. Stable overexpression of miR-7 and miR-218 was accompanied by reactivation of tumor suppressor genes including RASSF1A and Claudin-6 by means of epigenetic switches in DNA methylation and histone modification, giving rise to inhibition of the cell cycle and clone formation of breast cancer cells. The current study provides a novel link between overexpression of collinear Hox genes and multiple microRNAs in human breast malignancy.

  18. Efficient Management of Idleness in Systems Ningfang Mi

    E-Print Network [OSTI]

    Riska, Alma

    operate 24 hours a day, 7 days a week, it is becoming common to schedule maintenance jobs during idle is critical to system operation, yet their priority is not as high as that of foreground jobs, i are also collected. Resource management of idle times is now done in a dynamic way, using statistical

  19. Nanophotonic hybridization of narrow atomic cesium resonances and photonic stop gaps of opaline nanostructures

    E-Print Network [OSTI]

    Harding, Philip J; Mosk, Allard P; Vos, Willem L

    2014-01-01

    We study a hybrid system consisting of a narrowband atomic optical resonance and the long-range periodic order of an opaline photonic nanostructure. To this end, we have infiltrated atomic cesium vapor in a thin silica opal photonic crystal. With increasing temperature, the frequencies of the opal's reflectivity peaks shift down by >20% due to chemical reduction of the silica. Simultaneously, the photonic bands and gaps shift relative to the fixed near-infrared cesium D1 transitions. As a result the narrow atomic resonances with high finesse (f/df=8E5) dramatically change shape from a usual dispersive shape at the blue edge of a stop gap, to an inverted dispersion lineshape at the red edge of a stop gap. The lineshape, amplitude, and off-resonance reflectivity are well modeled with a transfer-matrix model that includes the dispersion and absorption of Cs hyperfine transitions and the chemically-reduced opal. An ensemble of atoms in a photonic crystal is an intriguing hybrid system that features narrow defect-...

  20. Saving Lives, Time and Resources tti.tamu.edu

    E-Print Network [OSTI]

    . TTI research is widely known as an excellent value with a proven impact of saving lives, time grounds facility, environmental and emissions facility and sediment and erosion control laboratory eight offices in Texas and offices in Ann Arbor, MI; Washington, D.C.; and Mexico City. TTI also has

  1. Walking, running, and resting under time, distance, and average speed constraints: Optimality of walk-run-rest mixtures

    E-Print Network [OSTI]

    Srinivasan, Manoj

    in a more ecological (non-treadmill) setting. We asked subjects to travel a given distance overground to go from your house to the bus stop and have very little time to do so. You would likely run the whole

  2. Strangeness suppression of <mi>q><mi>q>¯ creation observed in exclusive reactions

    SciTech Connect (OSTI)

    Mestayer, M. D.; Park, K.; Adhikari, K. P.; Aghasyan, M.; Pereira, S. Anefalos; Ball, J.; Battaglieri, M.; Batourine, V.; Bedlinskiy, I.; Biselli, A. S.; Boiarinov, S.; Briscoe, W. J.; Brooks, W. K.; Burkert, V. D.; Carman, D. S.; Celentano, A.; Chandavar, S.; Charles, G.; Colaneri, L.; Cole, P. L.; Contalbrigo, M.; Cortes, O.; Crede, V.; D’Angelo, A.; Dashyan, N.; De Vita, R.; Deur, A.; Djalali, C.; Doughty, D.; Dupre, R.; Alaoui, A. El; Fassi, L. El; Elouadrhiri, L.; Eugenio, P.; Fedotov, G.; Fleming, J. A.; Forest, T. A.; Garillon, B.; Garçon, M.; Ghandilyan, Y.; Gilfoyle, G. P.; Giovanetti, K. L.; Girod, F. X.; Goetz, J. T.; Golovatch, E.; Gothe, R. W.; Griffioen, K. A.; Guegan, B.; Guidal, M.; Hakobyan, H.; Hanretty, C.; Hattawy, M.; Holtrop, M.; Hughes, S. M.; Hyde, C. E.; Ilieva, Y.; Ireland, D. G.; Jiang, H.; Jo, H. S.; Joo, K.; Keller, D.; Khandaker, M.; Kim, A.; Kim, W.; Koirala, S.; Kubarovsky, V.; Kuleshov, S. V.; Lenisa, P.; Levine, W. I.; Livingston, K.; Lu, H. Y.; MacGregor, I. J. D.; Mayer, M.; McKinnon, B.; Meyer, C. A.; Mirazita, M.; Mokeev, V.; Montgomery, R. A.; Moody, C. I.; Moutarde, H.; Movsisyan, A.; Camacho, C. Munoz; Nadel-Turonski, P.; Niccolai, S.; Niculescu, G.; Niculescu, I.; Osipenko, M.; Ostrovidov, A. I.; Pappalardo, L. L.; Paremuzyan, R.; Peng, P.; Phelps, W.; Pisano, S.; Pogorelko, O.; Pozdniakov, S.; Price, J. W.; Protopopescu, D.; Puckett, A. J. R.; Raue, B. A.; Rimal, D.; Ripani, M.; Rizzo, A.; Rosner, G.; Roy, P.; Sabatié, F.; Saini, M. S.; Schott, D.; Schumacher, R. A.; Simonyan, A.; Sokhan, D.; Strauch, S.; Sytnik, V.; Tang, W.; Tian, Ye; Ungaro, M.; Vernarsky, B.; Vlassov, A. V.; Voskanyan, H.; Voutier, E.; Walford, N. K.; Watts, D. P.; Wei, X.; Weinstein, L. B.; Wood, M. H.; Zachariou, N.; Zhang, J.; Zhao, Z. W.; Zonta, I.

    2014-10-10

    In this study, we measured the ratios of electroproduction cross sections from a proton target for three exclusive meson-baryon final states: ?K+, p?0, and n?+, with the CLAS detector at Jefferson Lab. Using a simple model of quark hadronization, we extract qq¯ creation probabilities for the first time in exclusive two-body production, in which only a single qq¯ pair is created. We observe a sizable suppression of strange quark-antiquark pairs compared to nonstrange pairs, similar to that seen in high-energy production.

  3. PIANO DI RIQUALIFICAZIONE AMBIENTALE E PAESAGGISTICA DEL TERMOVALORIZZATORE DI DESIO TERMOVALORIZZATORE DI DESIO (MI) BRIANZA ENERGIA E AMBIENTE SPA

    E-Print Network [OSTI]

    Columbia University

    TERMOVALORIZZATORE DI DESIO (MI) ­ BRIANZA ENERGIA E AMBIENTE SPA Impianto di costruito negli anni '70 per lo. · Energia elettrica prodotta: 13.000.000 KWh/anno. LAND S.r.l. Landscape Architecture Nature Development

  4. Measurement of Pi-K Ratios from the NuMI Target

    SciTech Connect (OSTI)

    Seun, Sin Man; /Harvard U.

    2007-07-01

    Interactions of protons (p) with the NuMI (Neutrinos at the Main Injector) target are used to create the neutrino beam for the MINOS (Main Injector Neutrino Oscillation Search) Experiment. Using the MIPP (Main Injector Particle Production) experimental apparatus, the production of charged pions and kaons in p+NuMI interactions is studied. The data come from a sample of 2 x 10{sup 6} events obtained by MIPP using the 120 GeV/c proton beam from the Main Injector at Fermi National Accelerator Laboratory in Illinois, USA. Pions and kaons are identified by measurement in a Ring Imaging Cherenkov detector. Presented are measurements of {pi}{sup -}/{pi}{sup +}, K{sup -}/K{sup +}, {pi}{sup +}/K{sup +} and {pi}{sup -}/K{sup -} production ratios in the momentum range p{sub T} < 2 GeV/c transversely and 20 GeV/c < p{sub z} < 90 GeV/c longitudinally. Also provided are detailed comparisons of the MIPP NuMI data with the MIPP Thin Carbon data, the MIPP Monte Carlo simulation and the current MINOS models in the relevant momentum ranges.

  5. Targeting miR-21 enhances the sensitivity of human colon cancer HT-29 cells to chemoradiotherapy in vitro

    SciTech Connect (OSTI)

    Deng, Jun; Lei, Wan; Fu, Jian-Chun; Zhang, Ling; Li, Jun-He; Xiong, Jian-Ping

    2014-01-17

    Highlight: •MiR-21 plays a significant role in 5-FU resistance. •This role might be attributed to targeting of hMSH2 as well as TP and DPD via miR-21 targeted hMSH2. •Indirectly targeted TP and DPD to influence 5-FU chemotherapy sensitivity. -- Abstract: 5-Fluorouracil (5-FU) is a classic chemotherapeutic drug that has been widely used for colorectal cancer treatment, but colorectal cancer cells are often resistant to primary or acquired 5-FU therapy. Several studies have shown that miR-21 is significantly elevated in colorectal cancer. This suggests that this miRNA might play a role in this resistance. In this study, we investigated this possibility and the possible mechanism underlying this role. We showed that forced expression of miR-21 significantly inhibited apoptosis, enhanced cell proliferation, invasion, and colony formation ability, promoted G1/S cell cycle transition and increased the resistance of tumor cells to 5-FU and X radiation in HT-29 colon cancer cells. Furthermore, knockdown of miR-21 reversed these effects on HT-29 cells and increased the sensitivity of HT-29/5-FU to 5-FU chemotherapy. Finally, we showed that miR-21 targeted the human mutS homolog2 (hMSH2), and indirectly regulated the expression of thymidine phosphorylase (TP) and dihydropyrimidine dehydrogenase (DPD). These results demonstrate that miR-21 may play an important role in the 5-FU resistance of colon cancer cells.

  6. A study of nuclear stopping in central symmetric nuclear collisions at intermediate energies

    E-Print Network [OSTI]

    C. Escano-Rodriguez; D. Durand; A. Chbihi; J. D. Frankland; the INDRA Collaboration

    2005-03-14

    Nuclear stopping has been investigated in central symmetric nuclear collisions at intermediate energies. Firstly, it is found that the isotropy ratio, Riso, reaches a minimum near the Fermi energy and saturates or slowly increases depending on the mass of the system as the beam energy increases. An approximate scaling based on the size of the system is found above the Fermi energy suggesting the increasing role of in-medium nucleon-nucleon collisions. Secondly, the charge density distributions in velocity space, dZ/dvk and dZ/dv?, reveal a strong memory of the entrance channel and, as such, a sizeable nuclear transparency in the intermediate energy range. Lastly, it is shown that the width of the transverse velocity distribution is proportional to the beam velocity.

  7. High resolution time interval counter

    DOE Patents [OSTI]

    Condreva, K.J.

    1994-07-26

    A high resolution counter circuit measures the time interval between the occurrence of an initial and a subsequent electrical pulse to two nanoseconds resolution using an eight megahertz clock. The circuit includes a main counter for receiving electrical pulses and generating a binary word--a measure of the number of eight megahertz clock pulses occurring between the signals. A pair of first and second pulse stretchers receive the signal and generate a pair of output signals whose widths are approximately sixty-four times the time between the receipt of the signals by the respective pulse stretchers and the receipt by the respective pulse stretchers of a second subsequent clock pulse. Output signals are thereafter supplied to a pair of start and stop counters operable to generate a pair of binary output words representative of the measure of the width of the pulses to a resolution of two nanoseconds. Errors associated with the pulse stretchers are corrected by providing calibration data to both stretcher circuits, and recording start and stop counter values. Stretched initial and subsequent signals are combined with autocalibration data and supplied to an arithmetic logic unit to determine the time interval in nanoseconds between the pair of electrical pulses being measured. 3 figs.

  8. High resolution time interval counter

    DOE Patents [OSTI]

    Condreva, Kenneth J. (Livermore, CA)

    1994-01-01

    A high resolution counter circuit measures the time interval between the occurrence of an initial and a subsequent electrical pulse to two nanoseconds resolution using an eight megahertz clock. The circuit includes a main counter for receiving electrical pulses and generating a binary word--a measure of the number of eight megahertz clock pulses occurring between the signals. A pair of first and second pulse stretchers receive the signal and generate a pair of output signals whose widths are approximately sixty-four times the time between the receipt of the signals by the respective pulse stretchers and the receipt by the respective pulse stretchers of a second subsequent clock pulse. Output signals are thereafter supplied to a pair of start and stop counters operable to generate a pair of binary output words representative of the measure of the width of the pulses to a resolution of two nanoseconds. Errors associated with the pulse stretchers are corrected by providing calibration data to both stretcher circuits, and recording start and stop counter values. Stretched initial and subsequent signals are combined with autocalibration data and supplied to an arithmetic logic unit to determine the time interval in nanoseconds between the pair of electrical pulses being measured.

  9. MiR-34a targets GAS1 to promote cell proliferation and inhibit apoptosis in papillary thyroid carcinoma via PI3K/Akt/Bad pathway

    SciTech Connect (OSTI)

    Ma, Yanfei; Qin, Huadong [Department of Fourth Surgery, the Second Affiliated Hospital of Harbin Medical University, 148 Xuefu Road, Nangang District, Harbin 150086 (China)] [Department of Fourth Surgery, the Second Affiliated Hospital of Harbin Medical University, 148 Xuefu Road, Nangang District, Harbin 150086 (China); Cui, Yunfu, E-mail: yfma77@126.com [Department of First Surgery, the Second Affiliated Hospital of Harbin Medical University, 148 Xuefu Road, Nangang District, Harbin 150086 (China)] [Department of First Surgery, the Second Affiliated Hospital of Harbin Medical University, 148 Xuefu Road, Nangang District, Harbin 150086 (China)

    2013-11-29

    Highlights: •MiR-34a is up- and GAS1 is down-regulated in papillary thyroid carcinoma. •GAS1 is a direct target for miR-34a. •MiR-34a promotes PTC cells proliferation and inhibits apoptosis through PI3K/Akt/Bad pathway. -- Abstract: MicroRNAs (miRNAs) are fundamental regulators of cell proliferation, differentiation, and apoptosis, and are implicated in tumorigenesis of many cancers. MiR-34a is best known as a tumor suppressor through repression of growth factors and oncogenes. Growth arrest specific1 (GAS1) protein is a tumor suppressor that inhibits cancer cell proliferation and induces apoptosis through inhibition of RET receptor tyrosine kinase. Both miR-34a and GAS1 are frequently down-regulated in various tumors. However, it has been reported that while GAS1 is down-regulated in papillary thyroid carcinoma (PTC), miR-34a is up-regulated in this specific type of cancer, although their potential roles in PTC tumorigenesis have not been examined to date. A computational search revealed that miR-34a putatively binds to the 3?-UTR of GAS1 gene. In the present study, we confirmed previous findings that miR-34a is up-regulated and GAS1 down-regulated in PTC tissues. Further studies indicated that GAS1 is directly targeted by miR-34a. Overexpression of miR-34a promoted PTC cell proliferation and colony formation and inhibited apoptosis, whereas knockdown of miR-34a showed the opposite effects. Silencing of GAS1 had similar growth-promoting effects as overexpression of miR-34a. Furthermore, miR-34a overexpression led to activation of PI3K/Akt/Bad signaling pathway in PTC cells, and depletion of Akt reversed the pro-growth, anti-apoptotic effects of miR-34a. Taken together, our results demonstrate that miR-34a regulates GAS1 expression to promote proliferation and suppress apoptosis in PTC cells via PI3K/Akt/Bad pathway. MiR-34a functions as an oncogene in PTC.

  10. MiR-145 is downregulated in human ovarian cancer and modulates cell growth and invasion by targeting p70S6K1 and MUC1

    SciTech Connect (OSTI)

    Wu, Huijuan; Xiao, ZhengHua; Wang, Ke; Liu, Wenxin; Hao, Quan

    2013-11-29

    Highlights: •MiR-145 is downregulated in human ovarian cancer. •MiR-145 targets p70S6K1 and MUC1. •p70S6K1 and MUC1 are involved in miR-145 mediated tumor cell growth and cell invasion, respectively. -- Abstract: MicroRNAs (miRNAs) are a family of small non-coding RNA molecules that regulate gene expression at post-transcriptional levels. Previous studies have shown that miR-145 is downregulated in human ovarian cancer; however, the roles of miR-145 in ovarian cancer growth and invasion have not been fully demonstrated. In the present study, Northern blot and qRT-PCR analysis indicate that miR-145 is downregulated in ovarian cancer tissues and cell lines, as well as in serum samples of ovarian cancer, compared to healthy ovarian tissues, cell lines and serum samples. Functional studies suggest that miR-145 overexpression leads to the inhibition of colony formation, cell proliferation, cell growth viability and invasion, and the induction of cell apoptosis. In accordance with the effect of miR-145 on cell growth, miR-145 suppresses tumor growth in vivo. MiR-145 is found to negatively regulate P70S6K1 and MUC1 protein levels by directly targeting their 3?UTRs. Importantly, the overexpression of p70S6K1 and MUC1 can restore the cell colony formation and invasion abilities that are reduced by miR-145, respectively. MiR-145 expression is increased after 5-aza-CdR treatment, and 5-aza-CdR treatment results in the same phenotype as the effect of miR-145 overexpression. Our study suggests that miR-145 modulates ovarian cancer growth and invasion by suppressing p70S6K1 and MUC1, functioning as a tumor suppressor. Moreover, our data imply that miR-145 has potential as a miRNA-based therapeutic target for ovarian cancer.

  11. WHAT TO DO ABOUT CLIMATE CHANGE? Slowing the rate of carbon burning won't stop global warming

    E-Print Network [OSTI]

    Baez, John

    WHAT TO DO ABOUT CLIMATE CHANGE? #12;Slowing the rate of carbon burning won't stop global warming: most CO2 stays in the air over a century, though individual molecules come and go. Global warming. But we need to research it -- starting now. If global warming gets bad, public opinion may suddently flip

  12. Stopping of directed energetic electrons in high-temperature hydrogenic plasmas C. K. Li and R. D. Petrasso

    E-Print Network [OSTI]

    Stopping of directed energetic electrons in high-temperature hydrogenic plasmas C. K. Li and R. D, the interaction of directed energetic electrons with a high-temperature hydro- genic plasma is analytically modeled. The randomizing effect of scattering off both plasma ions and electrons is treated from a unified

  13. THE OBSTACLE PROBLEM FOR THE p-LAPLACIAN VIA OPTIMAL STOPPING OF TUG-OF-WAR GAMES

    E-Print Network [OSTI]

    Lewicka, Marta

    THE OBSTACLE PROBLEM FOR THE p-LAPLACIAN VIA OPTIMAL STOPPING OF TUG-OF-WAR GAMES MARTA LEWICKA-Laplace oper- ator. The solutions are approximated by running processes determined by tug-of-war games plus be used to write a formula similar to (1.3). Instead, we will show that one can use tug-of-war games

  14. Regression Model Predicting Appraised Unit Value of Land in San Francisco County from Number of and Distance to Public Transit Stops using GIS 

    E-Print Network [OSTI]

    Son, Kiyoung

    2012-07-16

    as the distance to LEED qualified bus stops light rail stops decreases. For residential zone, the appraised unit value increases as the number of LEED qualified bus and light rail stations increases. Furthermore, the appraised unit value increases as the distance...

  15. Testing CPT conservation using the NuMI neutrino beam with the MINOS experiment

    SciTech Connect (OSTI)

    Auty, David John; /Sussex U.

    2010-05-01

    The MINOS experiment was designed to measure neutrino oscillation parameters with muon neutrinos. It achieves this by measuring the neutrino energy spectrum and flavor composition of the man-made NuMI neutrino beam 1km after the beam is formed and again after 735 km. By comparing the two spectra it is possible to measure the oscillation parameters. The NuMI beam is made up of 7.0% {bar {nu}}{sub {mu}}, which can be separated from the {nu}{sub {mu}} because the MINOS detectors are magnetized. This makes it possible to study {bar {nu}}{sub {mu}} oscillations separately from those of muon neutrinos, and thereby test CPT invariance in the neutrino sector by determining the {bar {nu}}{sub {mu}} oscillation parameters and comparing them with those for {nu}{sub {mu}}, although any unknown physics of the antineutrino would appear as a difference in oscillation parameters. Such a test has not been performed with beam {bar {nu}}{sub {mu}} before. It is also possible to produce an almost pure {bar {nu}}{sub {mu}} beam by reversing the current through the magnetic focusing horns of the NuMI beamline, thereby focusing negatively, instead of positively charged particles. This thesis describes the analysis of the 7% {bar {nu}}{sub {mu}} component of the forward horn current NuMI beam. The {bar {nu}}{sub {mu}} of a data sample of 3.2 x 10{sup 20} protons on target analysis found 42 events, compared to a CPT conserving prediction of 58.3{sub -7.6}{sup +7.6}(stat.){sub -3.6}{sup +3.6}(syst.) events. This corresponds to a 1.9 {sigma} deficit, and a best fit value of {Delta}{bar m}{sub 32}{sup 2} = 18 x 10{sup -3} eV{sup 2} and sin{sup 2} 2{bar {theta}}{sub 23} = 0.55. This thesis focuses particularly on the selection of {bar {nu}}{sub {mu}} events, and investigates possible improvements of the selection algorithm. From this a different selector was chosen, which corroborated the findings of the original selector. The thesis also investigates how the systematic errors affect the precision of {Delta}{bar m}{sub 32}{sup 2} and sin{sup 2} 2{bar {theta}}{sub 23}. Furthermore, it describes a study to determine the gains of the PMTs via the single-photoelectron spectrum. The results were used as a crosscheck of the gains determined at higher intensities by an LED-based light-injection system.

  16. AMENDMENT OF SOLICITATION/MODIFICATlON OF CONTRACT MI54 I See Block 16C I

    National Nuclear Security Administration (NNSA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal GasAdministration Medal01 Sandia National 1 PAGE 1 OF2 AMENDMENTNLUF1 82 Se elBabcockMI54

  17. Adrenaline promotes cell proliferation and increases chemoresistance in colon cancer HT29 cells through induction of miR-155

    SciTech Connect (OSTI)

    Pu, Jun [Department of General Surgery, Tangdu Hospital of the Fourth Military Medical University, Xi'an 710038 (China)] [Department of General Surgery, Tangdu Hospital of the Fourth Military Medical University, Xi'an 710038 (China); Bai, Danna [Department of Cardiology, 323 Hospital of PLA, Xi'an 710054 (China)] [Department of Cardiology, 323 Hospital of PLA, Xi'an 710054 (China); Yang, Xia [Department of Teaching and Medical Administration, Tangdu Hospital of the Fourth Military Medical University, Xi'an 710038 (China)] [Department of Teaching and Medical Administration, Tangdu Hospital of the Fourth Military Medical University, Xi'an 710038 (China); Lu, Xiaozhao [Department of Nephrology, The 323 Hospital of PLA, Xi'an 710054 (China)] [Department of Nephrology, The 323 Hospital of PLA, Xi'an 710054 (China); Xu, Lijuan, E-mail: 13609296272@163.com [Department of Nephrology, The 323 Hospital of PLA, Xi'an 710054 (China)] [Department of Nephrology, The 323 Hospital of PLA, Xi'an 710054 (China); Lu, Jianguo, E-mail: lujianguo029@yahoo.com.cn [Department of General Surgery, Tangdu Hospital of the Fourth Military Medical University, Xi'an 710038 (China)] [Department of General Surgery, Tangdu Hospital of the Fourth Military Medical University, Xi'an 710038 (China)

    2012-11-16

    Highlights: Black-Right-Pointing-Pointer Adrenaline increases colon cancer cell proliferation and its resistance to cisplatin. Black-Right-Pointing-Pointer Adrenaline activates NF{kappa}B in a dose dependent manner. Black-Right-Pointing-Pointer NF{kappa}B-miR-155 pathway contributes to cell proliferation and resistance to cisplatin. -- Abstract: Recently, catecholamines have been described as being involved in the regulation of cancer genesis and progression. Here, we reported that adrenaline increased the cell proliferation and decreased the cisplatin induced apoptosis in HT29 cells. Further study found that adrenaline increased miR-155 expression in an NF{kappa}B dependent manner. HT29 cells overexpressing miR-155 had a higher cell growth rate and more resistance to cisplatin induced apoptosis. In contrast, HT29 cells overexpressing miR-155 inhibitor displayed decreased cell proliferation and sensitivity to cisplatin induced cell death. In summary, our study here revealed that adrenaline-NF{kappa}B-miR-155 pathway at least partially contributes to the psychological stress induced proliferation and chemoresistance in HT29 cells, shedding light on increasing the therapeutic strategies of cancer chemotherapy.

  18. Search for Stopped Gluinos in pp collisions at sqrt s = 7 TeV

    SciTech Connect (OSTI)

    Khachatryan, Vardan; et al.

    2011-01-01

    The results of the first search for long-lived gluinos produced in 7 TeV pp collisions at the CERN Large Hadron Collider are presented. The search looks for evidence of long-lived particles that stop in the CMS detector and decay in the quiescent periods between beam crossings. In a dataset with a peak instantaneous luminosity of 10^{32} cm^{-2} s^{-1}, an integrated luminosity of 10 inverse picobarns, and a search interval corresponding to 62 hours of LHC operation, no significant excess above background was observed. Limits at the 95% confidence level on gluino pair production over 13 orders of magnitude of gluino lifetime are set. For a mass difference between the gluino and the neutralino greater than 100 GeV/c^2, and assuming a branching ratio for gluino to gluon+neutralino of 100%, gluinos of mass less than 370 GeV/c^2 are excluded for lifetimes from 10 microseconds to 1000 s.

  19. Alternative process for thin layer etching: Application to nitride spacer etching stopping on silicon germanium

    SciTech Connect (OSTI)

    Posseme, N., E-mail: nicolas.posseme@cea.fr; Pollet, O.; Barnola, S. [CEA-LETI-Minatec, 17 rue des martyrs, 38054 Grenoble cedex 09 (France)

    2014-08-04

    Silicon nitride spacer etching realization is considered today as one of the most challenging of the etch process for the new devices realization. For this step, the atomic etch precision to stop on silicon or silicon germanium with a perfect anisotropy (no foot formation) is required. The situation is that none of the current plasma technologies can meet all these requirements. To overcome these issues and meet the highly complex requirements imposed by device fabrication processes, we recently proposed an alternative etching process to the current plasma etch chemistries. This process is based on thin film modification by light ions implantation followed by a selective removal of the modified layer with respect to the non-modified material. In this Letter, we demonstrate the benefit of this alternative etch method in term of film damage control (silicon germanium recess obtained is less than 6?A), anisotropy (no foot formation), and its compatibility with other integration steps like epitaxial. The etch mechanisms of this approach are also addressed.

  20. Assessment of radiological releases from the NuMI facility during MINOS and NOvA operations

    SciTech Connect (OSTI)

    Martens, Mike; /Fermilab

    2007-04-01

    This report makes projections of the radiological releases from the NuMI facility during operations for the MINOS and NO ?A experiments. It includes an estimate of the radionuclide levels released into the atmosphere and the estimated tritium and sodium-22 concentrations in the NuMI sump water and Fermilab pond system. The analysis was performed for NuMI operations with a beam power on target increased from the present 400 kW design up to a possible 1500 kW with future upgrades. The total number of protons on target was assumed to be 18 x 10{sup 20} after the completion of MINOS and 78 x 10{sup 20} after the completion of NO ?A.

  1. Upgrade of the Minos+ Experiment Data Acquisition for the High Energy NuMI Beam Run

    E-Print Network [OSTI]

    William Badgett; Steve R. Hahn; Donatella Torretta; Jerry Meier; Jeffrey Gunderson; Denise Osterholm; David Saranen

    2015-06-06

    The Minos+ experiment is an extension of the Minos experiment at a higher energy and more intense neutrino beam, with the data collection having begun in the fall of 2013. The neutrino beam is provided by the Neutrinos from the Main Injector (NuMI) beam-line at Fermi National Accelerator Laboratory (Fermilab). The detector apparatus consists of two main detectors, one underground at Fermilab and the other in Soudan, Minnesota with the purpose of studying neutrino oscillations at a base line of 735 km. The original data acquisition system has been running for several years collecting data from NuMI, but with the extended run from 2013, parts of the system needed to be replaced due to obsolescence, reliability problems, and data throughput limitations. Specifically, we have replaced the front-end readout controllers, event builder, and data acquisition computing and trigger processing farms with modern, modular and reliable devices with few single points of failure. The new system is based on gigabit Ethernet TCP/IP communication to implement the event building and concatenation of data from many front-end VME readout crates. The simplicity and partitionability of the new system greatly eases the debugging and diagnosing process. The new system improves throughput by about a factor of three compared to the old system, up to 800 megabits per second, and has proven robust and reliable in the current run.

  2. Anisotropic micro-cloths fabricated from DNA-stabilized carbon nanotubes: one-stop manufacturing with electrode needles

    E-Print Network [OSTI]

    Hiroshi Frusawa; Gen Yoshii

    2015-07-11

    Among a variety of solution-based approaches to fabricate anisotropic films of aligned carbon nanotubes (CNTs), we focus on the dielectrophoretic assembly method using AC electric fields in DNA-stabilized CNT suspensions. We demonstrate that a one-stop manufacturing system using electrode needles can draw anisotropic DNA-CNT hybrid films of 10-100 $\\mu$m in size (i.e., free-standing DNA-CNT micro-cloths) from the remaining suspension into the atmosphere while maintaining structural order. It has been found that a maximal degree of polarization (ca. 40 \\%) can be achieved by micro-cloths fabricated from a variety of DNA-CNT mixtures. Our results suggest that the one-stop method can impart biocompatibility to the downsized CNT films and that the DNA-stabilized CNT micro-cloths directly connected to an electrode could be useful for biofuel cells in terms of electron transfer and/or enzymatic activity.

  3. Particle distribution and nuclear stopping in Au-Au collisions at $\\sqrt{s_{NN}}$=200 GeV

    E-Print Network [OSTI]

    L. L. Zhu; C. B. Yang

    2006-05-18

    The transverse momentum distribution of produced charged particles is investigated for gold-gold collisions at $\\sqrt{s_{NN}}=200$ GeV. A simple parameterization is suggested for the particle distribution based on the nuclear stopping effect. The model can fit very well both the transverse momentum distributions at different pseudo-rapidities and the pseudo-rapidity distributions at different centralities. The ratio of rapidity distributions for peripheral and central collisions is calculated and compared with the data.

  4. LBL RUNAROUND RESULTS 3.00 km (1.86 mi) October 10, 1997 Place Time Name Group

    E-Print Network [OSTI]

    9:45.0 Etien, Robert Paul 30-39 1 3 10:04.8 Farias, Leonel 30-39 2 4:06.6 Volfbeyn, Paul , Jens 30-39 28 63 13:18.8 Lewis, Keith 40-49 5 64 13:19.1 Chou, Peter

  5. A phenomenological electronic stopping power model for molecular dynamics and Monte Carlo simulation of ion implantation into silicon

    E-Print Network [OSTI]

    Cai, D; Snell, C M; Beardmore, K M; Cai, David; Gronbech-Jensen, Niels; Snell, Charles M.; Beardmore, Keith M.

    1996-01-01

    It is crucial to have a good phenomenological model of electronic stopping power for modeling the physics of ion implantation into crystalline silicon. In the spirit of the Brandt-Kitagawa effective charge theory, we develop a model for electronic stopping power for an ion, which can be factorized into (i) a globally averaged effective charge taking into account effects of close and distant collisions by target electrons with the ion, and (ii) a local charge density dependent electronic stopping power for a proton. This phenomenological model is implemented into both molecular dynamics and Monte Carlo simulations. There is only one free parameter in the model, namely, the one electron radius rs0 for unbound electrons. By fine tuning this parameter, it is shown that the model can work successfully for both boron and arsenic implants. We report that the results of the dopant profile simulation for both species are in excellent agreement with the experimental profiles measured by secondary-ion mass spectrometry(...

  6. cis-and trans-Regulation of miR163 and Target Genes Confers Natural Variation of Secondary Metabolites in Two Arabidopsis

    E-Print Network [OSTI]

    Tholl, Dorothea

    involved in secondary metabolite biosynthetic pathways that are inducible by a fungal elicitor, alamethicin and secondary metabolite profiles. We suggest that cis- and trans-regulation of miRNA and other genes providescis- and trans-Regulation of miR163 and Target Genes Confers Natural Variation of Secondary

  7. Curcumin promotes apoptosis in A549/DDP multidrug-resistant human lung adenocarcinoma cells through an miRNA signaling pathway

    SciTech Connect (OSTI)

    Zhang, Jian, E-mail: zhangjian197011@yahoo.com [Department of Respiratory Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032 (China)] [Department of Respiratory Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032 (China); Zhang, Tao [Department of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038 (China)] [Department of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038 (China); Ti, Xinyu; Shi, Jieran; Wu, Changgui; Ren, Xinling [Department of Respiratory Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032 (China)] [Department of Respiratory Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032 (China); Yin, Hong, E-mail: yinnhong@yahoo.com [The Medical Image Center, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032 (China)] [The Medical Image Center, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032 (China)

    2010-08-13

    Research highlights: {yields} Curcumin had anti-cancer effects on A549/DDP multidrug-resistant human lung adenocarcinoma cells {yields} Curcumin promotes apoptosis in A549/DDP cells through a miRNA signaling pathway {yields} Curcumin induces A549/DDP cell apoptosis by downregulating miR-186* {yields} miR-186* may serve as a potential gene therapy target for refractory lung cancer that is sensitive to curcumin -- Abstract: Curcumin extracted from the rhizomes of Curcuma longa L. has been shown to have inhibitory effects on cancers through its anti-proliferative and pro-apoptotic activities. Emerging evidence demonstrates that curcumin can overcome drug resistance to classical chemotherapies. Thus, the mechanisms underlying the anti-tumor activities of curcumin require further study. In our study, we first demonstrated that curcumin had anti-cancer effects on A549/DDP multidrug-resistant human lung adenocarcinoma cells. Further studies showed that curcumin altered miRNA expression; in particular, significantly downregulated the expression of miR-186* in A549/DDP. In addition, transfection of cells with a miR-186* inhibitor promoted A549/DDP apoptosis, and overexpression of miR-186* significantly inhibited curcumin-induced apoptosis in A549/DDP cells. These observations suggest that miR-186* may serve as a potential gene therapy target for refractory lung cancer that is sensitive to curcumin.

  8. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne: OFFICE OF STUDENT FINANCIAL AID · The Welcome Center · P. O. Box 2340 · 42 West Warren · Detroit, MI

  9. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · www FINANCIAL AID · The Welcome Center · P. O. Box 2340 · 42 West Warren · Detroit, MI 48202-0340 If this form

  10. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · www OF STUDENT FINANCIAL AID · The Welcome Center · P. O. Box 2340 · 42 West Warren · Detroit, MI 48202-0340 3

  11. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne · Detroit, MI 48202-0340 Student's First Name 9-digit WSU Student ID # Student's Last Name Phone Number 3

  12. NUEX16 Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne FINANCIAL AID · The Welcome Center · P. O. Box 2340 · 42 West Warren · Detroit, MI 48202-0340 Student

  13. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · www · Detroit, MI 48202-0340 If this form is required it will be listed in Pipeline, under "My Requirements" 3

  14. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · www Warren · Detroit, MI 48202-0340 If this form is required it will be listed in Pipeline, under "My

  15. Manuscript was received April 15, 2007. Irina Hossain is with the Department of Electrical and Computer Engineering, Wayne State University, Detroit, MI. Phone: 651-815-5828; Fax: 651-

    E-Print Network [OSTI]

    Mahmud, Syed Masud

    and Computer Engineering, Wayne State University, Detroit, MI. Phone: 651-815-5828; Fax: 651- 305-4549; e State University, Detroit, MI. Phone: 313-577-3855; Fax: 313-577-5845; e-mail: smahmud

  16. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne Warren · Detroit, MI 48202-0340 Student's First Name 9-digit WSU Student ID # Student's Last Name Phone

  17. CTFS16 Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne · Detroit, MI 48202-0340 3/2015 Student's First Name 9-digit WSU Student ID # Student's Last Name Phone

  18. VRHS14 Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · www: OFFICE OF STUDENT FINANCIAL AID · The Welcome Center · P. O. Box 2340 · 42 West Warren · Detroit, MI

  19. Network Modeling Identifies Molecular Functions Targeted by miR-204 to Suppress Head and Neck Tumor

    E-Print Network [OSTI]

    Gerstein, Mark

    Network Modeling Identifies Molecular Functions Targeted by miR-204 to Suppress Head and Neck Tumor targets predicted by sequence-alignment databases and the relative low accuracy of such predictions which with tumor progression in squamous cell carcinoma of the head and neck (HNSCC). We further demonstrate

  20. Corrosion mechanisms of low level vitrified radioactive waste in a loamy soil M.I. Ojovan1

    E-Print Network [OSTI]

    Sheffield, University of

    Corrosion mechanisms of low level vitrified radioactive waste in a loamy soil M.I. Ojovan1 , W-sodium content radioactive waste borosilicate glass buried in a loamy soil (glass K-26) and in an open testing. This mechanism is likely to remain dominant until the decay of 137 Cs in the glass is below exemption levels

  1. A trans-homologue interaction between reciprocally imprinted miR-127 and Rtl1 regulates placenta development

    E-Print Network [OSTI]

    Ito, Mitsuteru; Sferruzzi-Perri, Amanda N.; Edwards, Carol A.; Adalsteinsson, Bjorn T.; Allen, Sarah E.; Loo, Tsui-Han; Kitazawa, Moe; Kaneko-Ishino, Tomoko; Ishino, Fumitoshi; Stewart, Colin L.; Ferguson-Smith, Anne C.

    2015-07-02

    ability of small molecules like oxygen to transfer by passive diffusion from mother to fetus (Laga et al., 1973). The TDC and SDC values of the mutant placentae indicate that ?miR-127 mice have a higher diffusive capacity than WTs and conversely...

  2. THE DARK SIDE OF SECURITY BY OBSCURITY and Cloning MiFare Classic Rail and Building Passes, Anywhere, Anytime

    E-Print Network [OSTI]

    International Association for Cryptologic Research (IACR)

    , Anywhere, Anytime Nicolas T. Courtois University College London, Computer Science, Gower street, WC1E 6BT, London, UK Keywords: Access control, RFID, contactless smart cards, MiFare Classic, London Oyster card- wide and in public transportation. For more than 10 years the specification of these cards was kept

  3. A note on tsunami amplitudes above submarine slides and slumps M.I. Todorovska*, A. Hayir1

    E-Print Network [OSTI]

    Southern California, University of

    A note on tsunami amplitudes above submarine slides and slumps M.I. Todorovska*, A. Hayir1 , M 2531, Los Angeles, CA 90089-2531, USA Accepted 27 October 2001 Abstract Tsunami generated by submarine functions. Tsunami waveforms for these models are computed using linearized shallow water theory

  4. Chiller Start/Stop Optimization for a Campus-wide Chilled Water System with a Thermal Storage Tank Under a Four-Period Electricity Rate Schedule 

    E-Print Network [OSTI]

    Zhou, J.; Wei, G.; Turner, W. D.; Deng, S.; Claridge, D.; Contreras, O.

    2002-01-01

    be expected, the complication in the rate structure also requires more involved control over the tank charging and discharging processes. A chiller start-stop optimization program has been developed and implemented into the Energy Management and Control System...

  5. Hunter College of the City University of New York Office of the Registrar One Stop, Room 217 North, 695 Park Avenue, NY 10065

    E-Print Network [OSTI]

    Qiu, Weigang

    Hunter College of the City University of New York ­ Office of the Registrar One Stop, Room 217# requires a signed Social Security Card. · If you have been declared a New York State Resident and you _______________________________________ Number and Street Address _____________________________________ City

  6. The PEANUT experiment in the NuMI beam at Fermilab

    SciTech Connect (OSTI)

    Russo, A. [Dipartimento di Scienze Fisiche, Universita Federico II di Napoli, 80125 Napoli (Italy)

    2010-03-30

    The PEANUT experiment was designed to study neutrino interactions in the few GeV range using the NuMI beam at Fermilab. The detector uses a hybrid technique, being made of nuclear emulsions and scintillator trackers. Emulsion films act as a tracking device and they are interleaved with lead plates used as neutrino targets. The detector is designed to reconstruct the topology of neutrino interactions at the single particle level. We present here the full reconstruction and analysis of a sample of 147 neutrino interactions that occurred in the PEANUT detector and the measurement of the quasielastic, resonance and deep-inelastic contributions to the total charged-current cross section. This technique could be applied for the beam monitoring at future neutrino facilities.

  7. T-1025 IU SciBath-768 detector tests in MI-12

    SciTech Connect (OSTI)

    Tayloe, Rex; Cooper, R.; Garrison, L.; Thornton, T.; Rebenitsch, L.; DeJongh, Fritz; Loer, Benjamin; Ramberg, Erik; Yoo, Jonghee; /Fermilab

    2012-02-11

    This is a memorandum of understanding between the Fermi National Accelerator Laboratory (Fermilab) and the experimenters of Department of Physics and Center for Exploration of Energy and Matter, Indiana University, who have committed to participate in detector tests to be carried out during the 2012 Fermilab Neutrino program. The memorandum is intended solely for the purpose of recording expectations for budget estimates and work allocations for Fermilab, the funding agencies and the participating institutions. it reflects an arrangement that currently is satisfactory to the parties; however, it is recognized and anticipated that changing circumstances of the evolving research program will necessitate revisions. The parties agree to modify this memorandum to reflect such required adjustments. Actual contractual obligations will be set forth in separate documents. The experimenters propsoe to test their prototype 'SciBat-768' detector in the MI-12 building for 3 months (February-April) in Spring 2012. The major goal of this effort is to measure or limit the flux of beam-induced neutrons in a far-off-axis (> 45{sup o}) location of the Booster Neutrino Beamline (BNB). This flux is of interest for a proposed coherent neutral-current neutrino-argon elastic scattering experiment. A second goal is to collect more test data for the SciBath-768 to enable better understanding and calibration of the device. The SciBath-768 detector successfully ran for 3 months in the MINOS Underground Area in Fall 2011 as testbeam experiment T-1014 and is currently running above ground in the MINOS service building. For the run proposed here, the experiments are requesting: space in MI-12 in which to run the SciBath detector during February-April 2012 while the BNB is operating; technical support to help with moving the equipment on site; access to power, internet, and accelerator signals; and a small office space from which to run and monitor the experiment.

  8. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    Office of Student Financial Aid The Welcome Center · 42 West Warren · P.O. Box 2340 · Detroit, MI. O. Box 2340 · 42 West Warren · Detroit, MI 48202-0340 2015-16 Verification of 2014 Income - Student · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne

  9. Time-aging time-stress superposition in soft glass under tensile deformation field

    E-Print Network [OSTI]

    Asima Shaukat; Ashutosh Sharma; Yogesh M. Joshi

    2010-06-10

    We have studied the tensile deformation behaviour of thin films of aging aqueous suspension of Laponite, a model soft glassy material, when subjected to a creep flow field generated by a constant engineering normal stress. Aqueous suspension of Laponite demonstrates aging behaviour wherein it undergoes time dependent enhancement of its elastic modulus as well as its characteristic relaxation time. However, under application of the normal stress, the rate of aging decreases and in the limit of high stress, the aging stops with the suspension now undergoing a plastic deformation. Overall, it is observed that the aging that occurs over short creep times at small normal stresses is same as the aging that occurs over long creep times at large normal stresses. This observation allows us to suggest an aging time - process time - normal stress superposition principle, which can predict rheological behaviour at longer times by carrying out short time tests.

  10. The Impact of Transportation Infrastructure on the Value of Time

    E-Print Network [OSTI]

    Barrett, James

    2010-01-01

    Minimum distance from home of light rail stop – Miles an eighth mile of home  LRD25 – Number of light rail stops a quarter mile of home  LRD5 – Number of light rail stops 

  11. Conserved Regulation of p53 Network Dosage by MicroRNA–125b Occurs through Evolving miRNA–Target Gene Pairs

    E-Print Network [OSTI]

    Le, Minh T. N.

    MicroRNAs regulate networks of genes to orchestrate cellular functions. MiR-125b, the vertebrate homologue of the Caenorhabditis elegans microRNA lin-4, has been implicated in the regulation of neural and hematopoietic ...

  12. {00012119.DOC /} Graduate Medical Education 540 E. Canfield Detroit, MI 48201 Phone 313-577-5189 Fax 313-577-5245

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    {00012119.DOC /} Graduate Medical Education 540 E. Canfield · Detroit, MI 48201 · Phone 313; This agreement of appointment by and between WSU, whose address is 540 East Canfield, Detroit, Michigan 48201

  13. ANRV253-MI59-05 ARI 21 April 2005 18:7 Diversity and Evolution of

    E-Print Network [OSTI]

    Plotkin, Joshua B.

    ANRV253-MI59-05 ARI 21 April 2005 18:7 R E V I E W S IN A D V A N CE Diversity and Evolution: pohlschr@sas.upenn.edu, njhand@sas.upenn.edu, kdilks@sas.upenn.edu, alexh@sas.upenn.edu 2 University of L. Rev. Microbiol. 2005. 59:91­111 doi: 10.1146/ annurev.micro.59.030804.121353 Copyright c 2005

  14. Three times geologist Adam Soule has climbed inside the deep-diving

    E-Print Network [OSTI]

    Oppo, Delia W.

    as the sub dives deeper. Deep-sea engineers often make crew compartments spherical. Because a sphere hasThree times geologist Adam Soule has climbed inside the deep-diving submersible Alvin and headed to the seafloor. Geochemist Susan Humphris stopped counting after 30 dives. Dan Fornari, who studies deep

  15. A SpaceTime Oriented Macroprogramming Paradigm for Push-Pull Hybrid Sensor Networking

    E-Print Network [OSTI]

    Suzuki, Jun

    , called SpaceTime Oriented Programming (STOP), is designed to reduce the complexity of WSN programming are deployed in a WSN, how nodes are connected with each other and how to route data queries in a WSN. Using that al- lows application developers to implement a WSN1 appli- cation from a global viewpoint as a whole

  16. Myc induced miR-144/451 contributes to the acquired imatinib resistance in chronic myelogenous leukemia cell K562

    SciTech Connect (OSTI)

    Liu, Li, E-mail: liuli029@yahoo.cn [Department of Hematology, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038 (China)] [Department of Hematology, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038 (China); Wang, Sitao; Chen, Renan; Wu, Yanlan; Zhang, Bei; Huang, Siyong; Zhang, Jingyi; Xiao, Fang; Wang, Meng; Liang, Yingmin [Department of Hematology, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038 (China)] [Department of Hematology, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038 (China)

    2012-08-24

    Highlights: Black-Right-Pointing-Pointer Increased c-myc expression in imatinib resistant CML cells. Black-Right-Pointing-Pointer c-myc contributes the imatinib resistance in CML cells. Black-Right-Pointing-Pointer c-myc transcriptionally reduces the expression of miR-144/451 in K562R cells. Black-Right-Pointing-Pointer Restoration of miR-144/451 reverses the resistance of K562R cells to imatinib. -- Abstract: Imatinib resistance remains the big hurdle for CML therapy. Previous study reveals that c-myc is important for bcr-abl CML cell proliferation, while its role in imatinib resistance is largely unknown. In this study, we first found that c-myc expression is upregulated in imatinib resistant K562R cells, which in turn enhances the expression of miR-144/451. Knockdown of c-myc or restoration of miR-144/451 in the K562R cells sensitizes K562R cells to imatinib therapy. Our study here reveals an regulatory pathway between myc and miR-144/451 and highlights that targeting either myc or miR-144/451 might be valuable for eliminating the imatinib resistant CML cells.

  17. February 1, 2004 Page 1 of 2 Stopping Germs at Home, Work and School

    E-Print Network [OSTI]

    Burke, Peter

    of coughs and sneezes. This is called "droplet spread." This can happen when droplets from a cough or sneeze coughing or sneezing Cough or sneeze into a tissue and then throw it away. Cover your cough or sneeze if you do not have a tissue. Then, clean your hands, and do so every time you cough or sneeze. The "Happy

  18. Collisions of low-energy antiprotons with molecular hydrogen: ionization, excitation and stopping power

    E-Print Network [OSTI]

    Lühr, Armin

    2008-01-01

    A time-dependent coupled-channel approach was used to calculate ionization, excitation, and energy-loss cross sections as well as energy spectra for antiproton and proton collisions with molecular hydrogen for impact energies 8 keV < E < 4000 keV.

  19. Don't Stop `Til You Get Enough: Adaptive Information Sampling in a Visuomotor Estimation Task

    E-Print Network [OSTI]

    Maloney, Laurence T.

    against the time, energy, or money spent collecting it. For example, Stigler (1961) analyzed the economic costs of prolonging a search for a better price on a commodity. Since a relatively cheap price is easily of finding the cheapest price. Instead, consumers should search only so long as the expected savings from

  20. Nano-hillock formation in diamond-like carbon induced by swift heavy projectiles in the electronic stopping regime: Experiments and atomistic simulations

    SciTech Connect (OSTI)

    Schwen, D.; Bringa, E.; Krauser, J.; Weidinger, A.; Trautmann, C.; Hofsaess, H.

    2012-09-10

    The formation of surface hillocks in diamond-like carbon is studied experimentally and by means of large-scale molecular dynamics simulations with 5 Multiplication-Sign 10{sup 6} atoms combined with a thermal spike model. The irradiation experiments with swift heavy ions cover a large electronic stopping range between {approx}12 and 72 keV/nm. Both experiments and simulations show that beyond a stopping power threshold, the hillock height increases linearly with the electronic stopping, and agree extremely well assuming an efficiency of approximately 20% in the transfer of electronic energy to the lattice. The simulations also show a transition of sp{sup 3} to sp{sup 2} bonding along the tracks with the hillocks containing almost no sp{sup 3} contribution.

  1. Stopped light with a cryogenic ensemble of {sup 173}Yb atoms

    SciTech Connect (OSTI)

    Lu Meiju; Jose, Franklin; Weinstein, Jonathan D. [Department of Physics, University of Nevada, Reno, Nevada 89557 (United States)

    2010-12-15

    A sample of cryogenically cooled atomic ytterbium is used to create a memory for a classical pulse of light. The information of the light pulse is stored in the nuclear spin of ground-state ({sup 1}S{sub 0}) {sup 173}Yb (I=5/2). Because nuclear spin states interact very weakly with their environment, the atomic ensemble is resistant to decoherence due to inelastic collisions and inhomogeneous fields, and storage times of hundreds of milliseconds are observed.

  2. Energy and Atomic Mass Dependence of Nuclear Stopping Power in Relativistic Heavy-Ion Collisions in Interacting Gluon Model

    E-Print Network [OSTI]

    Q. J. Liu; W. Q. Chao; G. Wilk

    1995-04-05

    We present a Monte-Carlo simulation of energy deposition process in relativistic heavy-ion collisions based on a new realization of the Interacting-Gluon-Model (IGM) for high energy $N-N$ collisions. In particular we show results for proton spectra from collisions of $E_{lab}=200 \\ GeV/N$ $^{32}$S beam incident on $^{32}$S target and analyze the energy and mass dependence of nuclear stopping power predicted by our model. Theoretical predictions for proton rapidity distributions of both $^{208}$Pb + $^{208}$Pb collisions at $E_{lab}=160 \\ GeV/N$ CERN SPS and $^{197}$Au + $^{197}$Au at $\\sqrt{s_{NN}}=200 \\ GeV$ BNL RHIC are given.

  3. SYMBOLS FOR TIME = time variable

    E-Print Network [OSTI]

    Duchowski, Andrew T.

    =forever) Cost spent to build variation point i at time i = index over variation points #12;SYMBOLS FOR TIME to account for net present value of money r = assumed interest rate i = index over variation points Cost Expected cost summed over all relevant time intervals Cost spent to build variation point i at time r

  4. Florida Sea Grant College Program http://www.flseagrant.org SGEF155 March 2009 rev. CAN WE STOP "KILLER ALGAE" FROM INVADING FLORIDA?

    E-Print Network [OSTI]

    Watson, Craig A.

    STOP "KILLER ALGAE" FROM INVADING FLORIDA? by Charles Jacoby 1 and Linda Walters 2 What is "killer algae"? The Mediterranean strain of Caulerpa taxifolia earned the name "killer algae" because of its devastating effects on the Mediterranean coast. The story of this algae or seaweed represents one of the best

  5. How to find Chair of Forest Ecology at ETH Zrich From main station you take tram 10 (with destination to "Flughafen" or "Oerlikon").The tram stop is

    E-Print Network [OSTI]

    Fischlin, Andreas

    How to find Chair of Forest Ecology at ETH Zürich From main station you take tram 10 (with the end of the corridor. To Main Station TramStop Haldenbach Tram 9 + 10 ETH Zürich Building CHN Universitätsstrasse 22 Hotel Sunnehus Sonneggstrasse 17 +41 44 250 27 27 ETH Main Building #12;Money exchange

  6. Date and Acquaintance Rape Risk Reduction Only people who rape have the power to STOP rape. There are some things you can do to

    E-Print Network [OSTI]

    Wong, Pak Kin

    Date and Acquaintance Rape Risk Reduction Only people who rape have the power to STOP rape and acquaintance rapes involve drugs and alcohol? · Mixing sexual decisions with drugs and alcohol can be risky to consent and you force them, it is rape. If your date is not conscious and you engage in sexual behaviors

  7. Influence of a strong laser field on Coulomb explosion and stopping power of energetic H{sub 3}{sup +} clusters in plasmas

    SciTech Connect (OSTI)

    Wang Guiqiu; Gao Hong; Wang Yaochuan; Yao Li; Zhong Haiyang; Cheng Lihong; Yang Kun; Liu Wei [Department of Physics, Dalian Maritime University, Dalian 116026 (China); E Peng; Xu Dianguo [Department of Electrical Engineering, Harbin Institute of Technology, Harbin 150001 (China); Wang Younian; Hu Zhanghu [School of Physics and Optoelectronic Technology, Dalian University of Technology, Dalian 116023 (China)

    2012-09-15

    The influence of a high-intensity laser field on the Coulomb explosion and stopping power for a swift H{sub 3}{sup +} cluster ion in a plasma target is studied by means of the molecular dynamic (MD) method based on the linearized Vlasov-Poisson theory. Excitations of the plasma are described by the classical plasma dielectric function. In the presence of the laser field, the general expressions for the induced potential in the target and the interaction force among the ions within the cluster are derived. Based on the numerical solution of the equations of motion for the constituent ions, the Coulomb explosion patterns and the cluster's stopping power are discussed for a range of laser parameters. Numerical results show that the laser field affects the correlation between the ions and contributes to weaken the wake effect and the stopping power as compared to the laser-free case. On the other hand, the stopping power ratio of H{sub 3}{sup +} cluster is higher than the situation of dicluster of H{sub 2}{sup +} due to the vicinage effect in the cluster.

  8. Stopped-Flow Studies of the Kinetics of Single-Stranded DNA Binding and Wrapping around the Escherichia coli SSB Tetramer

    E-Print Network [OSTI]

    Lohman, Timothy M.

    the Escherichia coli SSB Tetramer Alexander G. Kozlov and Timothy M. Lohman* Department of Biochemistry in which either one molecule of (dT)70 or two molecules of (dT)35 bind per tetramer. Stopped-flow studies. Our results indicate that initial ssDNA binding to the tetramer is very rapid, with a bimolecular rate

  9. OVMA 100th ANNUAL CONVENTION & EXPO -NORMAN -IT'S ON The Orange Power is in the house! Stop by the OSU CVHS exhibit booth at Embassy Suites Convention

    E-Print Network [OSTI]

    OVMA 100th ANNUAL CONVENTION & EXPO - NORMAN - IT'S ON The Orange Power is in the house! Stop a Companion Animal Program? Acknowledge the loss of client companion animals by making a contribution to the Companion Animal Fund. We make it easy. Contact me for a submission form, fill out the names of your client

  10. Near-optimal meanvariance controls under two-time-scale formulations and applications

    E-Print Network [OSTI]

    Zhang, Hongwei

    University, Detroit, MI 48202, USA; b Department of Electrical and Computer Engineering, Wayne State University, Detroit, MI 48202, USA; c Department of Computer Science, Wayne State University, Detroit, MI

  11. Modelling Time

    E-Print Network [OSTI]

    Burra G. Sidharth

    2008-09-03

    We briefly review two concepts of time - the usual time associated with "being" and more recent ideas, answering to the description of "becoming". The approximation involved in the former is examined. Finally we argue that it is (unpredictable) fluctuations that underlie time.

  12. Mitsubishi iMiEV: An Electric Mini-Car in NREL's Advanced Technology Vehicle Fleet (Fact Sheet)

    SciTech Connect (OSTI)

    Not Available

    2011-10-01

    This fact sheet highlights the Mitsubishi iMiEV, an electric mini-car in the advanced technology vehicle fleet at the National Renewable Energy Laboratory (NREL). In support of the U.S. Department of Energy's fast-charging research efforts, NREL engineers are conducting charge and discharge performance testing on the vehicle. NREL's advanced technology vehicle fleet features promising technologies to increase efficiency and reduce emissions without sacrificing safety or comfort. The fleet serves as a technology showcase, helping visitors learn about innovative vehicles that are available today or are in development. Vehicles in the fleet are representative of current, advanced, prototype, and emerging technologies.

  13. Quantum Time

    E-Print Network [OSTI]

    John Ashmead

    2010-05-05

    Normally we quantize along the space dimensions but treat time classically. But from relativity we expect a high level of symmetry between time and space. What happens if we quantize time using the same rules we use to quantize space? To do this, we generalize the paths in the Feynman path integral to include paths that vary in time as well as in space. We use Morlet wavelet decomposition to ensure convergence and normalization of the path integrals. We derive the Schr\\"odinger equation in four dimensions from the short time limit of the path integral expression. We verify that we recover standard quantum theory in the non-relativistic, semi-classical, and long time limits. Quantum time is an experiment factory: most foundational experiments in quantum mechanics can be modified in a way that makes them tests of quantum time. We look at single and double slits in time, scattering by time-varying electric and magnetic fields, and the Aharonov-Bohm effect in time.

  14. Precision Timing Via Cerenkov Radiation, S.E. Vahsen, C. Lu and K.T. McDonald

    E-Print Network [OSTI]

    McDonald, Kirk

    (TAC) 10 ns delay Stop Start Multi Channel Analyzer (MCA) beam splitter EG&G Ortec 9306 EG&G Ortec 9306 EG&G Ortec 9307 EG&G Ortec 9307 "Pico Timing" Discriminators Canberra Model 2145Spectrum ACE Computer Channel Analyzer (MCA) beam splitter EG&G Ortec 9306 1 GHz Preamplifier Semiconductor Photo Diode EG

  15. Miniature lightweight x-ray optics (MiXO) for surface elemental composition mapping of asteroids and comets

    E-Print Network [OSTI]

    Hong, Jaesub

    2016-01-01

    The compositions of diverse planetary bodies are of fundamental interest to planetary science, providing clues to the formation and evolutionary history of the target bodies and the Solar system as a whole. Utilizing the X-ray fluorescence unique to each atomic element, X-ray imaging spectroscopy is a powerful diagnostic tool of the chemical and mineralogical compositions of diverse planetary bodies. Until now the mass and volume of focusing X-ray optics have been too large for resource-limited in-situ missions, so near-target X-ray observations of planetary bodies have been limited to simple collimator-type X-ray instruments. We introduce a new Miniature lightweight Wolter-I focusing X-ray Optics (MiXO) using metal-ceramic hybrid X-ray mirrors based on electroformed nickel replication and plasma thermal spray processes. MiXO can enable compact, powerful imaging X-ray telescopes suitable for future planetary missions. We illustrate the need for focusing X-ray optics in observing relatively small planetary bod...

  16. Validation of nuclear models in Geant4 using the halo of a proton pencil beam stopping in water

    E-Print Network [OSTI]

    Hall, David C; Paganetti, Harald; Gottschalk, Bernard

    2015-01-01

    A proton pencil beam is associated with a surrounding low-dose envelope, originating from nuclear interactions. It is important for treatment planning systems to accurately model this envelope when performing dose calculations for pencil beam scanning treatments, and Monte Carlo (MC) codes are commonly used for this purpose. This work aims to validate the nuclear models employed by the Geant4 MC code, by comparing the simulated absolute dose distribution to a recent experiment of a 177 MeV proton pencil beam stopping in water. Impressive agreement is observed over five orders of magnitude, with both the shape and normalisation well modelled. The normalisations of two depth dose curves are lower than experiment, though this could be explained by an experimental positioning error. The Geant4 neutron production model is also verified in the distal region. The entrance dose is poorly modelled, suggesting an unaccounted upstream source of low-energy protons. Recommendations are given for a follow-up experiment whi...

  17. Kodama time

    E-Print Network [OSTI]

    Abreu, Gabriel

    2010-01-01

    In a general time-dependent (3+1)-dimensional spherically symmetric spacetime, the so-called Kodama vector is a naturally defined geometric quantity that is timelike outside the evolving horizon and so defines a preferred class of fiducial observers. However the Kodama vector does not by itself define any preferred notion of time. We demonstrate that a preferred time coordinate - which we shall call Kodama time - can be introduced by taking the additional step of applying the Clebsch decomposition theorem to the Kodama vector. We thus construct a geometrically preferred coordinate system for any time-dependent spherically symmetric spacetime, and explore its properties. In particular we use this formalism to construct a general class of conservation laws, generalizing Kodama's energy flux. We study the geometrically preferred fiducial observers, and demonstrate that it is possible to define and calculate a generalized notion of surface gravity that is valid throughout the entire evolving spacetime. Furthermor...

  18. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne Center · P. O. Box 2340 · 42 West Warren · Detroit, MI 48202-0340 3/2015 Student's First Name 9-digit WSU

  19. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne · The Welcome Center · P. O. Box 2340 · 42 West Warren · Detroit, MI 48202-0340 3/2015 Student's First Name 9

  20. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    Office of Student Financial Aid The Welcome Center · 42 West Warren · P.O. Box 2340 · Detroit, MI.O. Box 2340 · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · www

  1. Quantum time

    E-Print Network [OSTI]

    Giovannetti, Vittorio

    We give a consistent quantum description of time, based on Page and Wootters’s conditional probabilities mechanism, which overcomes the criticisms that were raised against similar previous proposals. In particular we show ...

  2. Chow Time 

    E-Print Network [OSTI]

    Unknown

    2011-09-05

    -1 THE PREDICTION OF BUS ARRIVAL TIME USING AUTOMATIC VEHICLE LOCATION SYSTEMS DATA A Dissertation by RAN HEE JEONG Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements for the degree... of DOCTOR OF PHILOSOPHY December 2004 Major Subject: Civil Engineering THE PREDICTION OF BUS ARRIVAL TIME USING AUTOMATIC VEHICLE LOCATION SYSTEMS DATA A Dissertation by RAN HEE JEONG Submitted to Texas A...

  3. Transport model study of nuclear stopping in heavy ion collisions over an energy range from 0.09A GeV to 160A GeV

    E-Print Network [OSTI]

    Ying Yuan; Qingfeng Li; Zhuxia Li; Fu-Hu Liu

    2010-02-26

    Nuclear stopping in the heavy ion collisions over a beam energy range from SIS, AGS up to SPS is studied in the framework of the modified UrQMD transport model, in which mean field potentials of both formed and "pre-formed" hadrons (from string fragmentation) and medium modified nucleon-nucleon elastic cross sections are considered. It is found that the nuclear stopping is influenced by both the stiffness of the equation of state and the medium modifications of nucleon-nucleon cross sections at SIS energies. At the high SPS energies, the two-bump structure is shown in the experimental rapidity distribution of free protons, which can be understood with the consideration of the "pre-formed" hadron potentials.

  4. Stop That Subversive Spreadsheet!

    E-Print Network [OSTI]

    David Chadwick

    2007-12-16

    This paper documents the formation of the European Spreadsheet Risks Interest Group (EuSpRIG www.eusprig.org) and outlines some of the research undertaken and reported upon by interested parties in EuSpRIG publications

  5. Projectile stopping system

    DOE Patents [OSTI]

    Karr, Thomas J. (Alamo, CA); Pittenger, Lee C. (Livermore, CA)

    1996-01-01

    A projectile interceptor launches a projectile catcher into the path of a projectile. In one embodiment, signals indicative of the path of a projectile are received by the projectile interceptor. A flinger mechanism has a projectile catcher releasably attached thereto, such that the projectile catcher can be released and launched from the flinger mechanism. A controller connected to the flinger mechanism uses the signals indicative of the path of the projectile to determine the launch parameters of the projectile catcher. The controller directs the flinger mechanism to release the projectile catcher such that the projectile catcher is launched into the path of the projectile and intercepts the projectile.

  6. Stop/Start: Overview

    Alternative Fuels and Advanced Vehicles Data Center [Office of Energy Efficiency and Renewable Energy (EERE)]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels Data Center Home PageBlenderBusiness Case forbuttonhighlighted Driving button

  7. Full Hybrid: Stopped

    Alternative Fuels and Advanced Vehicles Data Center [Office of Energy Efficiency and Renewable Energy (EERE)]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels Data Center HomeVehicle Replacement VouchersBraking buttonhighlightedBraking

  8. Stop/Start: Driving

    Alternative Fuels and Advanced Vehicles Data Center [Office of Energy Efficiency and Renewable Energy (EERE)]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels Data Center HomeVehicle Replacement VouchersBrakingHydrogen Vehicle NREL is

  9. Stop/Start: Overview

    Alternative Fuels and Advanced Vehicles Data Center [Office of Energy Efficiency and Renewable Energy (EERE)]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels Data Center HomeVehicle Replacement VouchersBrakingHydrogen Vehicle NREL

  10. Michigan State University | College of Engineering | Engineering Undergraduate Studies 1410 Engineering Building, East Lansing, MI 48824-1226 | (517) 355-6616 ext. 1

    E-Print Network [OSTI]

    (30) CEM 141 General Chemistry 4 EGR 100 Introduction to Engineering Design 2 EGR 102 IntroductionMichigan State University | College of Engineering | Engineering Undergraduate Studies 1410 Engineering Building, East Lansing, MI 48824-1226 | (517) 355-6616 ext. 1 http

  11. 50,000-Watt AM Stations IA | MB | MI | MN | NE | ND | ON | SD | WI | Station News | Owners | TV Captures | Links

    E-Print Network [OSTI]

    Allen, Gale

    that broadcast with a power of 50,000 Watts day and night. Some of these stations are what was once known50,000-Watt AM Stations IA | MB | MI | MN | NE | ND | ON | SD | WI | Station News | Owners | TV Captures | Links 50,000-Watt AM stations This list includes AM stations in the United States and Canada

  12. Michigan State University | College of Engineering | Engineering Undergraduate Studies Engineering Building, 428 S. Shaw Lane, Room 1415, East Lansing MI 48824 | (517) 355-6616 ext. 1

    E-Print Network [OSTI]

    Feeny, Brian

    Building, 428 S. Shaw Lane, Room 1415, East Lansing MI 48824 | (517) 355-6616 ext. 1 http 132 Calculus I 3 MTH 133 Calculus II 4 MTH 234 Multivariable Calculus 4 MTH 235 Differential Equations Energy Systems 3 ME 422 Introduction to Combustion 3 ME 423 Intermed Mech of Deformable Solids 3 ME 425

  13. Michigan State University | College of Engineering | Engineering Undergraduate Studies Engineering Building, 428 S. Shaw Lane, Room 1415, East Lansing MI 48824 | (517) 355-6616 ext. 1

    E-Print Network [OSTI]

    Building, 428 S. Shaw Lane, Room 1415, East Lansing MI 48824 | (517) 355-6616 ext. 1 http 234 Multivariable Calculus 4 MTH 235 Differential Equations 3 PHY 183 Physics for Scientists 450 International Environmental Law & Policy 3 ME 417 Design of Alternative Energy Systems 3 ME 422

  14. Michigan State University | College of Engineering | Engineering Undergraduate Studies Engineering Building, 428 S. Shaw Lane, Room 1415, East Lansing MI 48824 | (517) 355-6616 ext. 1

    E-Print Network [OSTI]

    Building, 428 S. Shaw Lane, Room 1415, East Lansing MI 48824 | (517) 355-6616 ext. 1 http to Engineering Modeling 2 MTH 132 Calculus I 3 MTH 133 Calculus II 4 MTH 234 Multivariable Calculus 4 MTH 235 4 CEM 161 Chemistry Laboratory I 1 CHE 201 Materials and Energy Balances 3 ENE 280 Principles

  15. Evaluation of Multiplexed 16S rRNA Microbial Population Surveys Using Illumina MiSeq Platform (Seventh Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting 2012)

    ScienceCinema (OSTI)

    Tremblay, Julien [DOE JGI

    2013-01-25

    Julien Tremblay from DOE JGI presents "Evaluation of Multiplexed 16S rRNA Microbial Population Surveys Using Illumina MiSeq Platorm" at the 7th Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting held in June, 2012 in Santa Fe, NM.

  16. Society of Automotive Engineers (SAE) Technical Paper 2006-01-1041 Paper presented at SAE 2006 World Congress & Exposition, April 5, 2006, Detroit, MI

    E-Print Network [OSTI]

    Gruner, Sol M.

    Society of Automotive Engineers (SAE) Technical Paper 2006-01-1041 Paper presented at SAE 2006 and Fundamental Advances in Thermal Fluid Sciences 2006. Vol. SP-2015. (Society of Automotive Engineers, Troy, MI and reducing emissions play an essential role in the design of the new-generation automotive internal

  17. Evaluation of Multiplexed 16S rRNA Microbial Population Surveys Using Illumina MiSeq Platform (Seventh Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting 2012)

    SciTech Connect (OSTI)

    Tremblay, Julien [DOE JGI] [DOE JGI

    2012-06-01

    Julien Tremblay from DOE JGI presents "Evaluation of Multiplexed 16S rRNA Microbial Population Surveys Using Illumina MiSeq Platorm" at the 7th Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting held in June, 2012 in Santa Fe, NM.

  18. A library of MiMICs allows tagging of genes and reversible, spatial and temporal knockdown of proteins in Drosophila

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Nagarkar-Jaiswal, Sonal; Lee, Pei-Tseng; Campbell, Megan E.; Chen, Kuchuan; Anguiano-Zarate, Stephanie; Cantu Gutierrez, Manuel; Busby, Theodore; Lin, Wen-Wen; He, Yuchun; Schulze, Karen L.; et al

    2015-03-31

    Here, we document a collection of ~7434 MiMIC (Minos Mediated Integration Cassette) insertions of which 2854 are inserted in coding introns. They allowed us to create a library of 400 GFP-tagged genes. We show that 72% of internally tagged proteins are functional, and that more than 90% can be imaged in unfixed tissues. Moreover, the tagged mRNAs can be knocked down by RNAi against GFP (iGFPi), and the tagged proteins can be efficiently knocked down by deGradFP technology. The phenotypes associated with RNA and protein knockdown typically correspond to severe loss of function or null mutant phenotypes. Finally, we demonstratemore »reversible, spatial, and temporal knockdown of tagged proteins in larvae and adult flies. This new strategy and collection of strains allows unprecedented in vivo manipulations in flies for many genes. These strategies will likely extend to vertebrates.« less

  19. Behavior-Based Simulation Approach for the Capacity and Traffic Operational Characteristic Study of Four-Way-Stop-Controlled Intersections

    E-Print Network [OSTI]

    Yin, Juan

    2010-08-26

    and service time. After calibration and validation, the simulation model was used to study characteristics of the queue length, control delay, and service time at FWSC intersections. Finally, intersection capacities were estimated under different traffic...

  20. Recoding of the stop codon UGA to glycine by a BD1-5/SN-2 bacterium and niche partitioning between Alpha- and Gammaproteobacteria in a tidal sediment microbial community naturally selected in a laboratory chemostat

    SciTech Connect (OSTI)

    Hanke, Anna; Hamann, Emmo; Sharma, Ritin; Geelhoed, Jeanine; Hargesheimer, Theresa; Kraft, Beate; Meyer, Volker; Lenk, Sabine; Osmers, Harald; Wu, Rong; Makinwa, Kofi; Hettich, Robert {Bob} L; Banfield, Jillian F.; Tegetmeyer, Halina; Strouss, Marc

    2014-01-01

    Sandy coastal sediments are global hot spots for microbial mineralization of organic matter and denitrification. These sediments are characterized by advective pore water flow, tidal cycling and an active and complex microbial community. Metagenomic sequencing of microbial communities sampled from such sediments showed that potential sulfuroxidizing Gammaproteobacteria and members of the enigmaticBD1-5/ SN-2 candidatephylumwereabundantinsitu (>10% and 2% respectively). By mimicking the dynamic oxic/anoxic environmental conditions of the sedimentin a laboratory chemostat, a simplified microbial community was selected from the more complex inoculum. Metagenomics, proteomics and fluorescenceinsituhybridization showed that this simplified community contained both a potential sulfuroxidizing Gamma proteobacteria (at 24 2% abundance) and a member of the BD1-5 / SN-2candidatephylum (at 7 6%abundance). Despite the abundant supply of organic substrates to the chemostat, proteomic analysis suggested that the selected gamma proteobacterium grew partially auto trophically and performed hydrogen/formate oxidation. The enrichment of a member of the BD1-5/SN-2candidatephylum enabled, for the first time, direct microscopic observation by fluorescent insitu hybridization and the experimental validation of the previously predicted translation of the stop codon UGA into glycine.

  1. A study of muon neutrino disappearance with the MINOS detectors and the NuMI neutrino beam

    SciTech Connect (OSTI)

    Marshall, John Stuart; /Cambridge U.

    2008-06-01

    This thesis presents the results of an analysis of {nu}{sub {mu}} disappearance with the MINOS experiment, which studies the neutrino beam produced by the NuMI facility at Fermi National Accelerator Laboratory. The rates and energy spectra of charged current {nu}{sub {mu}} interactions are measured in two similar detectors, located at distances of 1 km and 735 km along the NuMI beamline. The Near Detector provides accurate measurements of the initial beam composition and energy, while the Far Detector is sensitive to the effects of neutrino oscillations. The analysis uses data collected between May 2005 and March 2007, corresponding to an exposure of 2.5 x 10{sup 20} protons on target. As part of the analysis, sophisticated software was developed to identify muon tracks in the detectors and to reconstruct muon kinematics. Events with reconstructed tracks were then analyzed using a multivariate technique to efficiently isolate a pure sample of charged current {nu}{sub {mu}} events. An extrapolation method was also developed, which produces accurate predictions of the Far Detector neutrino energy spectrum, based on data collected at the Near Detector. Finally, several techniques to improve the sensitivity of an oscillation measurement were implemented, and a full study of the systematic uncertainties was performed. Extrapolating from observations at the Near Detector, 733 {+-} 29 Far Detector events were expected in the absence of oscillations, but only 563 events were observed. This deficit in event rate corresponds to a significance of 4.3 standard deviations. The deficit is energy dependent and clear distortion of the Far Detector energy spectrum is observed. A maximum likelihood analysis, which fully accounts for systematic uncertainties, is used to determine the allowed regions for the oscillation parameters and identifies the best fit values as {Delta}m{sub 32}{sup 2} = 2.29{sub -0.14}{sup +0.14} x 10{sup -3} eV{sup 2} and sin{sup 2} 2{theta}{sub 23} > 0.953 (68% confidence level). The models of neutrino decoherence and decay are disfavored at the 5.0{sigma} and 3.2{sigma} levels respectively, while the no oscillation model is excluded at the 9.4{sigma} level.

  2. MiX: A Position Sensitive Dual-Phase Liquid Xenon Detector

    E-Print Network [OSTI]

    Stephenson, S; Lin, Q; Ni, K; Pushkin, K; Raymond, R; Schubnell, M; Shutty, N; Tarlé, G; Weaverdyck, C; Lorenzon, W

    2015-01-01

    The need for precise characterization of dual-phase xenon detectors has grown as the technology has matured into a state of high efficacy for rare event searches. The Michigan Xenon detector was constructed to study the microphysics of particle interactions in liquid xenon across a large energy range in an effort to probe aspects of radiation detection in liquid xenon. We report the design and performance of a small 3D position sensitive dual-phase liquid xenon time projection chamber with high light yield ($L_y^{122}=15.2 $pe/keV at zero field), long electron lifetime ($\\tau > 200 \\mu$s), and excellent energy resolution ($\\sigma/E = 1\\%$ for 1,333 keV gamma rays in a drift field of 200 V/cm). Liquid xenon time projection chambers with such high energy resolution may find applications not only in dark matter direct detection searches, but also in neutrinoless double beta decay experiments and other applications.

  3. Dispatch R427 Time perception: Brain time or event time?

    E-Print Network [OSTI]

    Johnston, Alan

    Dispatch R427 Time perception: Brain time or event time? Alan Johnston* and Shin'ya Nishida Recent experiments show that synchronous events can appear to an observer to occur at different times. Neural processing time delays are offered as an explanation of these temporal illusions, but equating perceived time

  4. Time Management Managing Time and Tasks

    E-Print Network [OSTI]

    Kunkle, Tom

    Time Management Managing Time and Tasks What is time management? Time can't be managed ­ but you can manage the amount of time you use each day for fun, work, rest, and time spent with others. Why is time management important? You have responsibilities to yourself, to your family and friends, to your

  5. Reconfiguration of Manhattan Bus Stopping Frequency Objective: Perform research and field studies that evaluate the energy and cost saving

    E-Print Network [OSTI]

    Wolberg, George

    --that describes a way to improve transportation effectiveness while simultaneously reducing air pollution, energy, air, and climate change. In the realm of sustainable transportation, one promising response, more atmospheric pollution, and slower times to passenger destinations--especially when aggregated over

  6. Approach to Recover Hydrocarbons from Currently Off-Limit Areas of the Antrim Formation, MI Using Low-Impact Technologies

    SciTech Connect (OSTI)

    James Wood; William Quinlan

    2008-09-30

    The goal of this project was to develop and execute a novel drilling and completion program in the Antrim Shale near the western shoreline of Northern Michigan. The target was the gas in the Lower Antrim Formation (Upper Devonian). Another goal was to see if drilling permits could be obtained from the Michigan DNR that would allow exploitation of reserves currently off-limits to exploration. This project met both of these goals: the DNR (Michigan Department of Natural Resources) issued permits that allow drilling the shallow subsurface for exploration and production. This project obtained drilling permits for the original demonstration well AG-A-MING 4-12 HD (API: 21-009-58153-0000) and AG-A-MING 4-12 HD1 (API: 21-009-58153-0100) as well as for similar Antrim wells in Benzie County, MI, the Colfax 3-28 HD and nearby Colfax 2-28 HD which were substituted for the AG-A-MING well. This project also developed successful techniques and strategies for producing the shallow gas. In addition to the project demonstration well over 20 wells have been drilled to date into the shallow Antrim as a result of this project's findings. Further, fracture stimulation has proven to be a vital step in improving the deliverability of wells to deem them commercial. Our initial plan was very simple; the 'J-well' design. We proposed to drill a vertical or slant well 30.48 meters (100 feet) below the glacial drift, set required casing, then angle back up to tap the resource lying between the base to the drift and the conventional vertical well. The 'J'-well design was tested at Mancelona Township in Antrim County in February of 2007 with the St. Mancelona 2-12 HD 3.

  7. Linear electronic field time-of-flight ion mass spectrometers

    DOE Patents [OSTI]

    Funsten, Herbert O. (Los Alamos, NM)

    2010-08-24

    Time-of-flight mass spectrometer comprising a first drift region and a second drift region enclosed within an evacuation chamber; a means of introducing an analyte of interest into the first drift region; a pulsed ionization source which produces molecular ions from said analyte of interest; a first foil positioned between the first drift region and the second drift region, which dissociates said molecular ions into constituent atomic ions and emits secondary electrons; an electrode which produces secondary electrons upon contact with a constituent atomic ion in second drift region; a stop detector comprising a first ion detection region and a second ion detection region; and a timing means connected to the pulsed ionization source, to the first ion detection region, and to the second ion detection region.

  8. Emission spectra and invariant masses of Lambda and p in the stopped-K-NN absorption process in 4He and 6Li

    E-Print Network [OSTI]

    Toshimitsu Yamazaki; Yoshinori Akaishi

    2007-06-10

    We have calculated the emission spectra of Y and N and invariant masses of YN pairs in the direct K-NN --> YN absorption process at rest in 4He and light nuclei in order to provide theoretical tools for correct interpretations of experimental data with or without invoking kaonic nuclear bound states. All the momentum distributions are broad with widths around 150-200 MeV/c (except for the case of 6Li target), while the partial invariant mass of each YN pair has a peak around 2310-2330 MeV/c2. We argue against the interpretations of stopped-K- experimental data of KEK and FINUDA by Oset and Toki and by Magas, Oset, Ramos and Toki.

  9. Forward Lambda production and nuclear stopping power in d+Au collisions at root s(NN)=200 GeV 

    E-Print Network [OSTI]

    Abelev, B. I.; Aggarwal, M. M.; Ahammed, Z.; Anderson, B. D.; Arkhipkin, D.; Averichev, G. S.; Bai, Y.; Balewski, J.; Barannikova, O.; Barnby, L. S.; Baudot, J.; Baumgart, S.; Belaga, V. V.; Bellingeri-Laurikainen, A.; Bellwied, R.; Benedosso, F.; Betts, R. R.; Bhardwaj, S.; Bhasin, A.; Bhati, A. K.; Bichsel, H.; Bielcik, J.; Bielcikova, J.; Bland, L. C.; Blyth, S. -L; Bombara, M.; Bonner, B. E.; Botje, M.; Bouchet, J.; Brandin, A. V.; Bravar, A.; Burton, T. P.; Bystersky, M.; Cai, X. Z.; Caines, H.; Sanchez, M. Calderon de la Barca; Callner, J.; Catu, O.; Cebra, D.; Cervantes, M. C.; Chajecki, Z.; Chaloupka, P.; Chattopadhyay, S.; Chen, H. F.; Chen, J. H.; Chen, J. Y.; Cheng, J.; Cherney, M.; Chikanian, A.; Christie, W.; Chung, S. U.; Clarke, R. F.; Codrington, M. J. M.; Coffin, J. P.; Cormier, T. M.; Cosentino, M. R.; Cramer, J. G.; Crawford, H. J.; Das, D.; Dash, S.; Daugherity, M.; de Moura, M. M.; Dedovich, T. G.; DePhillips, M.; Derevschikov, A. A.; Didenko, L.; Dietel, T.; Djawotho, P.; Dogra, S. M.; Dong, X.; Drachenberg, J. L.; Draper, J. E.; Du, F.; Dunin, V. B.; Dunlop, J. C.; Mazumdar, M. R. Dutta; Eckardt, V.; Edwards, W. R.; Efimov, L. G.; Emelianov, V.; Engelage, J.; Eppley, G.; Erazmus, B.; Estienne, M.; Fachini, P.; Fatemi, R.; Fedorisin, J.; Feng, A.; Filip, P.; Finch, E.; Fine, V.; Fisyak, Y.; Fu, J.; Gagliardi, Carl A.; Gaillard, L.; Ganti, M. S.; Garcia-Solis, E.; Ghazikhanian, V.; Ghosh, P.; Gorbunov, Y. N.; Gos, H.; Grebenyuk, O.; Grosnick, D.; Grube, B.; Guertin, S. M.; Guimaraes, K. S. F. F.; Gupta, N.; Haag, B.; Hallman, T. J.; Hamed, A.; Harris, J. W.; He, W.; Heinz, M.; Henry, T. W.; Heppelmann, S.; Hippolyte, B.; Hirsch, A.; Hjort, E.; Hoffman, A. M.; Hoffmann, G. W.; Hofman, D. J.; Hollis, R. S.; Horner, M. J.; Huang, H. Z.; Hughes, E. W.; Humanic, T. J.; Igo, G.; Iordanova, A.; Jacobs, P.; Jacobs, W. W.; Jakl, P.; Jia, F.; Jones, P. G.; Judd, E. G.; Kabana, S.; Kang, K.; Kapitan, J.; Kaplan, M.; Keane, D.; Kechechyan, A.; Kettler, D.; Khodyrev, V. Yu; Kiryluk, J.; Kisiel, A.; Kislov, E. M.; Klein, S. R.; Knospe, A. G.; Kocoloski, A.; Koetke, D. D.; Kollegger, T.; Kopytine, M.; Kotchenda, L.; Kouchpil, V.; Kowalik, K. L.; Kravtsov, P.; Kravtsov, V. I.; Krueger, K.; Kuhn, C.; Kulikov, A. I.; Kumar, A.; Kurnadi, P.; Kuznetsov, A. A.; Lamont, M. A. C.; Landgraf, J. M.; Lange, S.; LaPointe, S.; Laue, F.; Lauret, J.; Lebedev, A.; Lednicky, R.; Lee, C. -H; Lehocka, S.; LeVine, M. J.; Li, C.; Li, Q.; Li, Y.; Lin, G.; Lin, X.; Lindenbaum, S. J.; Lisa, M. A.; Liu, F.; Liu, H.; Liu, J.; Liu, L.; Ljubicic, T.; Llope, W. J.; Longacre, R. S.; Love, W. A.; Lu, Y.; Ludlam, T.; Lynn, D.; Ma, G. L.; Ma, J. G.; Ma, Y. G.; Mahapatra, D. P.; Majka, R.; Mangotra, L. K.; Manweiler, R.; Margetis, S.; Markert, C.; Martin, L.; Matis, H. S.; Matulenko, Yu A.; McClain, C. J.; McShane, T. S.; Melnick, Yu; Meschanin, A.; Millane, J.; Miller, M. L.; Minaev, N. G.; Mioduszewski, Saskia; Mischke, A.; Mitchell, J.; Mohanty, B.; Morozov, D. A.; Munhoz, M. G.; Nandi, B. K.; Nattrass, C.; Nayak, T. K.; Nelson, J. M.; Nepali, C.; Netrakanti, P. K.; Nogach, L. V.; Nurushev, S. B.; Odyniec, G.; Ogawa, A.; Okorokov, V.; Oldenburg, M.; Olson, D.; Pachr, M.; Pal, S. K.; Panebratsev, Y.; Pavlinov, A. I.; Pawlak, T.; Peitzmann, T.; Perevoztchikov, V.; Perkins, C.; Peryt, W.; Phatak, S. C.; Planinic, M.; Pluta, J.; Poljak, N.; Porile, N.; Poskanzer, A. M.; Potekhin, M.; Potrebenikova, E.; Potukuchi, B. V. K. S.; Prindle, D.; Pruneau, C.; Pruthi, N. K.; Putschke, J.; Qattan, I. A.; Raniwala, R.; Raniwala, S.; Ray, R. L.; Relyea, D.; Ridiger, A.; Ritter, H. G.; Roberts, J. B.; Rogachevskiy, O. V.; Romero, J. L.; Rose, A.; Roy, C.; Ruan, L.; Russcher, M. J.; Sahoo, R.; Sakrejda, I.; Sakuma, T.; Salur, S.; Sandweiss, J.; Sarsour, M.; Sazhin, P. S.; Schambach, J.; Scharenberg, R. P.; Schmitz, N.; Seger, J.; Selyuzhenkov, I.; Seyboth, P.; Shabetai, A.; Shahaliev, E.; Shao, M.; Sharma, M.; Shen, W. Q.; Shimanskiy, S. S.; Sichtermann, E. P.; Simon, F.; Singaraju, R. N.; Smirnov, N.; Snellings, R.; Sorensen, P.; Sowinski, J.; Speltz, J.; Spinka, H. M.; Srivastava, B.; Stadnik, A.; Stanislaus, T. D. S.; Staszak, D.; Stock, R.; Strikhanov, M.; Stringfellow, B.; Suaide, A. A. P.; Suarez, M. C.; Subba, N. L.; Sumbera, M.; Sun, X. M.; Sun, Z.; Surrow, B.; Symons, T. J. M.; De Toledo, A. Szanto; Takahashi, J.; Tang, A. H.; Tarnowsky, T.; Thomas, J. H.; Timmins, A. R.; Timoshenko, S.; Tokarev, M.; Trainor, T. A.; Trentalange, S.; Tribble, Robert E.; Tsai, O. D.; Ulery, J.; Ullrich, T.; Underwood, D. G.; Van Buren, G.; Van der Kolk, N.; Van Leeuwen, M.; Molen, A. M. Vander; Varma, R.; Vasilevski, I. M.; Vasiliev, A. N.; Vernet, R.; Vigdor, S. E.; Viyogi, Y. P.; Vokal, S.; Voloshin, S. A.; Wada, M.

    2007-01-01

    REVIEW C 76, 064904 (2007) Forward ? production and nuclear stopping power in d+Au collisions at?sNN = 200 GeV B. I. Abelev,9 M. M. Aggarwal,30 Z. Ahammed,45 B. D. Anderson,20 D. Arkhipkin,13 G. S. Averichev,12 Y. Bai,28 J. Balewski,17 O. Barannikova,9...,22 M. Bombara,2 B. E. Bonner,36 M. Botje,28 J. Bouchet,40 A. V. Brandin,26 A. Bravar,3 T. P. Burton,2 M. Bystersky,11 X. Z. Cai,39 H. Caines,50 M. Caldero?n de la Barca Sa?nchez,6 J. Callner,9 O. Catu,50 D. Cebra,6 M. C. Cervantes,41 Z. Chajecki,29...

  10. UGE Scheduler Cycle Time

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    UGE Scheduler Cycle Time UGE Scheduler Cycle Time Genepool Cycle Time Genepool Daily Genepool Weekly Phoebe Cycle Time Phoebe Daily Phoebe Weekly What is the Scheduler Cycle? The...

  11. Time and Labor Manual -Time Keepers -LSUSH

    E-Print Network [OSTI]

    Time and Labor Manual - Time Keepers - LSUSH Version Date: July 2012 #12;COPYRIGHT & TRADEMARKS create a risk of personal injury. If you use this software in dangerous applications, then you shall Guide Time and Labor Manual - Time Keepers - LSUSH Page iii Table of Contents Time and Labor Manual

  12. Time Commitments Where Does Your Time Go

    E-Print Network [OSTI]

    Kunkle, Tom

    Time Commitments Where Does Your Time Go Everyone starts the week with the same number of hours. So, why does your time go so fast? Let's find out! Number of hours of sleep each night ____ x 7 preparation/clean-up time) ____ x 7 = ____ Travel time to and from campus ___ x __ = ____ Number of hours per

  13. Balancing particle absorption with structural support of the muon beam stop in muons-to-electrons experimental chamber

    SciTech Connect (OSTI)

    Majewski, Ryan

    2013-01-01

    The Mu2e experiment at Fermi National Accelerator Laboratory is seeking a full conversion from muon to electron. The design for Mu2e is based off MECO, another proposed experiment that sought a full conversion from muon to electron at Brookhaven National Laboratory in the 1990s. Mu2e will provide sensitivity that is four times the sensitivity of the previous experiment, SINDRUM II. Discovering muon to electron conversions could help explain physics beyond the standard model of the particle physics.

  14. Arsenite evokes IL-6 secretion, autocrine regulation of STAT3 signaling, and miR-21 expression, processes involved in the EMT and malignant transformation of human bronchial epithelial cells

    SciTech Connect (OSTI)

    Luo, Fei; Xu, Yuan; Ling, Min; Zhao, Yue; Xu, Wenchao; Liang, Xiao; Jiang, Rongrong; Wang, Bairu; Bian, Qian; Liu, Qizhan

    2013-11-15

    Arsenite is an established human carcinogen, and arsenite-induced inflammation contributes to malignant transformation of cells, but the molecular mechanisms by which cancers are produced remain to be established. The present results showed that, evoked by arsenite, secretion of interleukin-6 (IL-6), a pro-inflammatory cytokine, led to the activation of STAT3, a transcription activator, and to increased levels of a microRNA, miR-21. Blocking IL-6 with anti-IL-6 antibody and inhibiting STAT3 activation reduced miR-21 expression. For human bronchial epithelial cells, cultured in the presence of anti-IL-6 antibody for 3 days, the arsenite-induced EMT and malignant transformation were reversed. Thus, IL-6, acting on STAT3 signaling, which up-regulates miR-21in an autocrine manner, contributes to the EMT induced by arsenite. These data define a link from inflammation to EMT in the arsenite-induced malignant transformation of HBE cells. This link, mediated through miRNAs, establishes a mechanism for arsenite-induced lung carcinogenesis. - Highlights: • Arsenite evokes IL-6 secretion. • IL-6 autocrine mediates STAT3 signaling and up-regulates miR-21expression. • Inflammation is involved in arsenite-induced EMT.

  15. Forward Lambda Production and Nuclear Stopping Power in d + Au Collisions at sqrt(s_NN) = 200 GeV

    E-Print Network [OSTI]

    STAR Collaboration; B. I. Abelev

    2007-12-21

    We report the measurement of Lamda and Anti-Lamda yields and inverse slope parameters in d + Au collisions at sqrt(s_NN) = 200 GeV at forward and backward rapidities (y = +- 2.75), using data from the STAR forward time projection chambers. The contributions of different processes to baryon transport and particle production are probed exploiting the inherent asymmetry of the d + Au system. Comparisons to model calculations show that the baryon transport on the deuteron side is consistent with multiple collisions of the deuteron nucleons with gold participants. On the gold side HIJING based models do not describe the measured particle yields while models with initial state nuclear effects and/or hadronic rescattering do. The multichain model can provide a good description of the net baryon density in d + Au collisions at energies available at the BNL Relativistic Heavy Ion Collider, and the derived parameters of the model agree with those from nuclear collisions at lower energies.

  16. Forward Lambda Production and Nuclear Stopping Power in d + Au Collisions at sqrt(s_NN) = 200 GeV

    E-Print Network [OSTI]

    Abelev, B I; Ahammed, Z; Anderson, B D; Arkhipkin, D; Averichev, G S; Bai, Y; Balewski, J; Barannikova, O; Barnby, L S; Baudot, J; Baumgart, S; Belaga, V V; Bellingeri-Laurikainen, A; Bellwied, R; Benedosso, F; Betts, R R; Bhardwaj, S; Bhasin, A; Bhati, A K; Bichsel, H; Bielcik, J; Bielcikova, J; Bland, L C; Blyth, S L; Bombara, M; Bonner, B E; Botje, M; Bouchet, J; Brandin, A V; Bravar, A; Burton, T P; Bystersky, M; Cai, X Z; Caines, H; Calderón de la Barca-Sanchez, M; Callner, J; Catu, O; Cebra, D; Cervantes, M C; Chajecki, Z; Chaloupka, P; Chattopadhyay, S; Chen, H F; Chen, J H; Chen, J Y; Cheng, J; Cherney, M; Chikanian, A; Christie, W; Chung, S U; Clarke, R F; Codrington, M J M; Coffin, J P; Cormier, T M; Cosentino, M R; Cramer, J G; Crawford, H J; Das, D; Dash, S; Daugherity, M; De Moura, M M; Dedovich, T G; De Phillips, M; Derevshchikov, A A; Didenko, L; Dietel, T; Djawotho, P; Dogra, S M; Dong, X; Drachenberg, J L; Draper, J E; Du, F; Dunin, V B; Dunlop, J C; Dutta-Majumdar, M R; Eckardt, V; Edwards, W R; Efimov, L G; Emelianov, V; Engelage, J; Eppley, G; Erazmus, B; Estienne, M; Fachini, P; Fatemi, R; Fedorisin, J; Feng, A; Filip, P; Finch, E; Fine, V; Fisyak, Yu; Fu, J; Gagliardi, C A; Gaillard, L; Ganti, M S; García-Solis, E; Ghazikhanian, V; Ghosh, P; Gorbunov, Y N; Gos, H; Grebenyuk, O; Grosnick, D; Grube, B; Guertin, S M; Guimaraes, K S F F; Gupta, N; Haag, B; Hallman, T J; Hamed, A; Harris, J W; He, W; Heinz, M; Henry, T W; Heppelmann, S; Hippolyte, B; Hirsch, A; Hjort, E; Hoffman, A M; Hoffmann, G W; Hofman, D J; Hollis, R S; Horner, M J; Huang, H Z; Hughes, E W; Humanic, T J; Igo, G; Iordanova, A; Jacobs, P; Jacobs, W W; Jakl, P; Jia, F; Jones, P G; Judd, E G; Kabana, S; Kang, K; Kapitan, J; Kaplan, M; Keane, D; Kechechyan, A; Kettler, D; Khodyrev, V Yu; Kiryluk, J; Kisiel, A; Kislov, E M; Klein, S R; Knospe, A G; Kocoloski, A; Koetke, D D; Kollegger, T; Kopytine, M; Kotchenda, L; Kouchpil, V; Kowalik, K L; Kravtsov, P; Kravtsov, V I; Krüger, K; Kuhn, C; Kulikov, A I; Kumar, A; Kurnadi, P; Kuznetsov, A A; Lamont, M A C; Landgraf, J M; Lange, S; La Pointe, S; Laue, F; Lauret, J; Lebedev, A; Lednicky, R; Lee, C H; Lehocka, S; Le Vine, M J; Li, C; Li, Q; Li, Y; Lin, G; Lin, X; Lindenbaum, S J; Lisa, M A; Liu, F; Liu, H; Liu, J; Liu, L; Ljubicic, T; Llope, W J; Longacre, R S; Love, W A; Lu, Y; Ludlam, T; Lynn, D; Ma, G L; Ma, J G; Ma, Y G; Mahapatra, D P; Majka, R; Mangotra, L K; Manweiler, R; Margetis, S; Markert, C; Martin, L; Matis, H S; Matulenko, Yu A; McClain, C J; McShane, T S; Melnik, Yu M; Meschanin, A; Millane, J; Miller, M L; Minaev, N G; Mioduszewski, S; Mischke, A; Mitchell, J; Mohanty, B; Morozov, D A; Munhoz, M G; Nandi, B K; Nattrass, C; Nayak, T K; Nelson, J M; Nepali, C; Netrakanti, P K; Nogach, L V; Nurushev, S B; Odyniec, Grazyna Janina; Ogawa, A; Okorokov, V; Oldenburg, M; Olson, D; Pachr, M; Pal, S K; Panebratsev, Yu A; Pavlinov, A I; Pawlak, T; Peitzmann, T; Perevozchikov, V; Perkins, C; Peryt, W; Phatak, S C; Planinic, M; Pluta, J; Poljak, N; Porile, N; Poskanzer, A M; Potekhin, M V; Potrebenikova, E V; Potukuchi, B V K S; Prindle, D; Pruneau, C; Pruthi, N K; Putschke, J; Qattan, I A; Raniwala, R; Raniwala, S; Ray, R L; Relyea, D; Ridiger, A; Ritter, H G; Roberts, J B; Rogachevski, O V; Romero, J L; Rose, A; Roy, C; Ruan, L; Russcher, M J; Sahoo, R; Sakrejda, I; Sakuma, T; Salur, S; Sandweiss, J; Sarsour, M; Sazhin, P S; Schambach, J; Scharenberg, R P; Schmitz, N; Seger, J; Selyuzhenkov, I; Seyboth, P; Shabetai, A; Shahaliev, E; Shao, M; Sharma, M; Shen, W Q; Shimansky, S S; Sichtermann, E P; Simon, F; Singaraju, R N; Smirnov, N; Snellings, R; Sørensen, P; Sowinski, J; Speltz, J; Spinka, H M; Srivastava, B; Stadnik, A; Stanislaus, T D S; Staszak, D; Stock, R; Strikhanov, M N; Stringfellow, B C; Suaide, A A P; Suarez, M C; Subba, N L; Sumbera, M; Sun, X M; Sun, Z; Surrow, B; Symons, T J M; Szanto de Toledo, A; Takahashi, J; Tang, A H; Tarnowsky, T J; Thomas, J H; Timmins, A R; Timoshenko, S; Tokarev, M; Trainor, T A; Trentalange, S; Tribble, R E; Tsai, O D; Ulery, J; Ullrich, T; Underwood, D G; Van Buren, G; Van der Kolk, N; Van Leeuwen, M; Van der Molen, A M; Varma, R; Vasilevski, I M; Vasilev, A N; Vernet, R; Vigdor, S E; Viyogi, Y P; Vokal, S; Voloshin, S A; Wada, M; Waggoner, W T; Wang, F; Wang, G; Wang, J S; Wang, X L; Wang, Y; Webb, J C; Westfall, G D; Whitten, C; Wieman, H; Wissink, S W; Witt, R; Wu, J; Wu, Y; Xu, N; Xu, Q H; Xu, Z; Yepes, P; Yoo, I K; Yue, Q; Yurevich, V I; Zawisza, M; Zhan, W; Zhang, H; Zhang, W M; Zhang, Y; Zhang, Z P; Zhao, Y; Zhong, C; Zhou, J; Zoulkarneev, R; Zoulkarneeva, Y; Zubarev, A N; Zuo, J X

    2007-01-01

    We report the measurement of Lamda and Anti-Lamda yields and inverse slope parameters in d + Au collisions at sqrt(s_NN) = 200 GeV at forward and backward rapidities (y = +- 2.75), using data from the STAR forward time projection chambers. The contributions of different processes to baryon transport and particle production are probed exploiting the inherent asymmetry of the d + Au system. Comparisons to model calculations show that the baryon transport on the deuteron side is consistent with multiple collisions of the deuteron nucleons with gold participants. On the gold side HIJING based models do not describe the measured particle yields while models with initial state nuclear effects and/or hadronic rescattering do. The Multi-Chain Model can provide a good description of the net baryon density in d + Au collisions at RHIC, and the derived parameters of the model agree with those from nuclear collisions at lower energies.

  17. Development of a one-stop beam verification system using electronic portal imaging devices for routine quality assurance

    SciTech Connect (OSTI)

    Lim, Sangwook; Ma, Sun Young; Jeung, Tae Sig; Yi, Byong Yong; Lee, Sang Hoon; Lee, Suk; Cho, Sam Ju; Choi, Jinho

    2012-10-01

    In this study, a computer-based system for routine quality assurance (QA) of a linear accelerator (linac) was developed by using the dosimetric properties of an amorphous silicon electronic portal imaging device (EPID). An acrylic template phantom was designed such that it could be placed on the EPID and be aligned with the light field of the collimator. After irradiation, portal images obtained from the EPID were transferred in DICOM format to a computer and analyzed using a program we developed. The symmetry, flatness, field size, and congruence of the light and radiation fields of the photon beams from the linac were verified simultaneously. To validate the QA system, the ion chamber and film (X-Omat V2; Kodak, New York, NY) measurements were compared with the EPID measurements obtained in this study. The EPID measurements agreed with the film measurements. Parameters for beams with energies of 6 MV and 15 MV were obtained daily for 1 month using this system. It was found that our QA tool using EPID could substitute for the film test, which is a time-consuming method for routine QA assessment.

  18. Ecloud Build-Up Simulations for the FNAL MI for a Mixed Fill Pattern: Dependence on Peak SEY and Pulse Intensity During the Ramp

    SciTech Connect (OSTI)

    Furman, M. A.

    2010-12-11

    We present simulation results of the build-up of the electron-cloud density n{sub e} in three regions of the FNAL Main Injector (MI) for a beam fill pattern made up of 5 double booster batches followed by a 6th single batch. We vary the pulse intensity in the range N{sub t} = (2-5) x 10{sup 13}, and the beam kinetic energy in the range E{sub k} = 8-120 GeV. We assume a secondary electron emission model qualitatively corresponding to TiN, except that we let the peak value of the secondary electron yield (SEY) {delta}{sub max} vary as a free parameter in a fairly broad range. Our main conclusions are: (1) At fixed N{sub t} there is a clear threshold behavior of n{sub e} as a function of {delta}{sub max} in the range {approx} 1.1-1.3. (2) At fixed {delta}{sub max}, there is a threshold behavior of n{sub e} as a function of N{sub t} provided {delta}{sub max} is sufficiently high; the threshold value of N{sub t} is a function of the characteristics of the region being simulated. (3) The dependence on E{sub k} is weak except possibly at transition energy. Most of these results were informally presented to the relevant MI personnel in April 2010.

  19. Time Crystals from Minimum Time Uncertainty

    E-Print Network [OSTI]

    Mir Faizal; Mohammed M. Khalil; Saurya Das

    2014-12-29

    Motivated by the Generalized Uncertainty Principle, covariance, and a minimum measurable time, we propose a deformation of the Heisenberg algebra, and show that this leads to corrections to all quantum mechanical systems. We also demonstrate that such a deformation implies a discrete spectrum for time. In other words, time behaves like a crystal.

  20. Twenty times lower ignition threshold for laser driven fusion using collective effects and the inhibition factor

    SciTech Connect (OSTI)

    Hora, H. [Department of Theoretical Physics, University of New South Wales, Sydney 2052 (Australia); Malekynia, B.; Ghoranneviss, M. [Plasma Physics Research Center, Science and Research Branch, Islamic Azad University, Tehran-Poonak 14835-159 (Iran, Islamic Republic of); Miley, G. H. [Department of Nuclear, Plasma and Radiological Engineering, University of Illinois, Urbana, Illinois 61801 (United States); He, X. [Institute of Applied Physics and Computational Mathematics, Beijing 100088 (China)

    2008-07-07

    Hydrodynamic analysis for ignition of inertial fusion by Chu [Phys. Fluids 15, 413 (1972)] arrived at extremely high thresholds of a minimum energy flux density E* at 4x10{sup 8} J/cm{sup 2} which could be provided, e.g., by spark ignition. In view of alternative schemes of fast ignition, a re-evaluation of the early analysis including later discovered collective stopping power and the inhibition factor results in a 20 times lowering of the threshold for E*.

  1. Space time and the passage of time

    E-Print Network [OSTI]

    George F. R. Ellis; Rituparno Goswami

    2012-08-26

    This paper examines the various arguments that have been put forward suggesting either that time does not exist, or that it exists but its flow is not real. I argue that (i) time both exists and flows; (ii) an Evolving Block Universe (`EBU') model of spacetime adequately captures this feature, emphasizing the key differences between the past, present, and future; (iii) the associated surfaces of constant time are uniquely geometrically and physically determined in any realistic spacetime model based in General Relativity Theory; (iv) such a model is needed in order to capture the essential aspects of what is happening in circumstances where initial data does not uniquely determine the evolution of spacetime structure because quantum uncertainty plays a key role in that development. Assuming that the functioning of the mind is based in the physical brain, evidence from the way that the mind apprehends the flow of time prefers this evolving time model over those where there is no flow of time.

  2. Manage Your Time 

    E-Print Network [OSTI]

    White, Lynn

    2000-06-27

    People view time in different ways, but we all could do a better job of managing our time. This publication explains three different time management tools: the 24-hour time log and chart; a self-assessment of thinking styles and time management...

  3. \\\\mi\\home\\gillow\\LaTeX\\Comp\\Safety\\Risk-Assessments\\Roof\\Sedum Roof Area Roof Access Risk Assessments 3th March 2014.docx `Sedum' Roof Area(s)/Roof Access Risk Assessments

    E-Print Network [OSTI]

    \\\\mi\\home\\gillow\\LaTeX\\Comp\\Safety\\Risk-Assessments\\Roof\\Sedum Roof Area Roof Access Risk Assessments 3th March 2014.docx `Sedum' Roof Area(s)/Roof Access Risk Assessments DEPARTMENT: Andrew Wiles March 2015 Brief description of area and location Roof tops, walkways, and Fire Route. Sedum' Roof Area

  4. 1.Physics Department, Colorado School of Mines, Golden, CO 2. National Renewable Energy Laboratory, Golden, CO 3. United Solar Ovonic, LLC Troy, MI, United States THERMAL ACTIVATION OF DEEP OXYGEN DEFECT FORMATION AND HYDROGEN EFFUSION

    E-Print Network [OSTI]

    1.Physics Department, Colorado School of Mines, Golden, CO 2. National Renewable Energy Laboratory, Golden, CO 3. United Solar Ovonic, LLC Troy, MI, United States BACKGROUND THERMAL ACTIVATION OF DEEP was partially supported by a DOE grant through United Solar Ovonics, Inc., under the Solar America Initiative

  5. Page 274 Courses: Chemistry (CHEM) Sonoma State University 2015-2016 Catalog CHeM 125A QuAntitAtive generAL CHeMiStry (5)

    E-Print Network [OSTI]

    Ravikumar, B.

    Page 274 Courses: Chemistry (CHEM) Sonoma State University 2015-2016 Catalog CHeM 125A QuAntitAtive generAL CHeMiStry (5) Lecture, 3 hours; discussion 1 hour; laboratory 3 hours (5 units). This one-year analytical general chemistry course is designed for freshmen Chemistry majors, Biochemistry majors, or others

  6. Stopping Cooling Flows with Jets

    E-Print Network [OSTI]

    Fabrizio Brighenti; William G. Mathews

    2006-01-24

    We describe 2D gasdynamical models of jets that carry mass as well as energy to the hot gas in galaxy clusters. These flows have many attractive attributes for solving the galaxy cluster cooling flow problem: Why the hot gas temperature and density profiles resemble cooling flows but show no spectral evidence of cooling to low temperatures. Using an approximate model for the cluster A1795, we show that mass-carrying jets can reduce the overall cooling rate to or below the low values implied by X-ray spectra. Biconical subrelativistic jets, described with several ad hoc parameters, are assumed to be activated when gas flows toward or cools near a central supermassive black hole. As the jets proceed out from the center they entrain more and more ambient gas. The jets lose internal pressure by expansion and are compressed by the ambient cluster gas, becoming rather difficult to observe. For a wide variety of initial jet parameters and several feedback scenarios the global cooling can be suppressed for many Gyrs while maintaining cluster temperature profiles similar to those observed. The intermittancy of the feedback generates multiple generations of X-ray cavities similar to those observed in the Perseus Cluster and elsewhere.

  7. On Time. 6b: Quantum Mechanical Time

    E-Print Network [OSTI]

    C. K. Raju

    2008-08-09

    The existence of small amounts of advanced radiation, or a tilt in the arrow of time, makes the basic equations of physics mixed-type functional differential equations. The novel features of such equations point to a microphysical structure of time. This corresponds to a change of logic at the microphysical level. We show that the resulting logic is a quantum logic. This provides a natural and rigorous explanation of quantum interference. This structured-time interpretation of quantum mechanics is briefly compared with various other interpretations of q.m.

  8. Prompt Neutron Time Decay in Single HEU and DU Metal Annular Storage Castings

    SciTech Connect (OSTI)

    Pena, Kirsten E [ORNL] [ORNL; McConchie, Seth M [ORNL] [ORNL; Mihalczo, John T [ORNL] [ORNL

    2010-01-01

    Previous measurements of highly enriched uranium (HEU) storage castings performed by Oak Ridge National Laboratory (ORNL) at the Y-12 National Security Complex showed a prompt neutron time decay that is not exponential. These measurements showed that multiple time constants originating from multiplication, time-of-flight, scattering in the assembly and room return could be associated with this prompt neutron decay. In this work, the contribution not associated with neutron multiplication was investigated via measurements with a depleted uranium (DU) casting. The measurements at ORNL used an annular (5.0-in OD, 3.5-in ID, 6.0-in H) DU casting with a time-tagged 252Cf source, centered vertically on the axis, and four closely coupled 1 1 6-in.-long plastic scintillators with -in.- thick lead shielding adjacent to the outer surface of the casting. This setup was identical to the configuration used in the previously performed measurements with HEU castings at Y-12. The time correlation between fission events and detections in the plastic scintillators was measured, as well as the time distribution of coincidences between multiple detectors within a 512-ns time window. The measurement results were then compared to MCNP-PoliMi calculations and the previous HEU measurements. Time constants from decay fits to the HEU and DU data were compared to characterize the contributions resulting from multiplication, time-of-flight, and scattering.

  9. Sensitivity Analysis of Combustion Timing of Homogeneous

    E-Print Network [OSTI]

    Stefanopoulou, Anna

    efficiency 2 . As a result, HCCI engines achieve fuel economy levels comparable to that of compression Engines Chia-Jui Chiang Department of Mechanical Engineering, National Taiwan University of Science of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109 e-mail: annastef@umich.edu The goal

  10. Yet another time about time - Part I

    E-Print Network [OSTI]

    Plamen L. Simeonov

    2015-08-29

    This paper presents yet another personal reflection on one the most important concepts in both science and the humanities: time. This elusive notion has been not only bothering philosophers since Plato and Aristotle. It goes throughout human history embracing all analytical and creative (anthropocentric) disciplines. Time has been a central theme in physical and life sciences, philosophy, psychology, music, art and many more. This theme is known with a vast body of knowledge across different theories and categories. What has been explored concerns its nature (rational, irrational, arational), appearances/qualia, degrees, dimensions and scales of conceptualization (internal, external, fractal, discrete, continuous, mechanical, quantum, local, global, etc.). Of particular interest have been parameters of time such as duration ranges, resolutions, modes (present, now, past, future), varieties of tenses (e.g. present perfect, present progressive, etc.) and some intuitive, but also fancy phenomenological characteristics such as arrow, stream, texture, width, depth, density, even scent. Perhaps the most distinct characteristic of this fundamental concept is the absolute time constituting the flow of consciousness according to Husserl, the reflection of pure (human) nature without having the distinction between exo and endo. This essay is a personal reflection upon the meaning of time in modern physics and phenomenological philosophy.

  11. Universal Time Tunneling

    E-Print Network [OSTI]

    Guenter Nimtz

    2009-01-26

    How much time does a tunneling wave packet spent in traversing a barrier? Quantum mechanical calculations result in zero time inside a barrier . In the nineties analogous tunneling experiments with microwaves were carried out. The results agreed with quantum mechanical calculations. Electron tunneling time is hard to measure being extremely short and parasitic effects due to the electric charge of electrons may be dominant. However, quite recently the atomic ionization tunneling time has been measured. Experimental data of photonic, phononic, and electronic tunneling time is available now and will be presented. It appears that the tunneling time is a universal property independent of the field in question.

  12. Time Asymmetric Quantum Physics

    E-Print Network [OSTI]

    A. Bohm

    1999-02-26

    Mathematical and phenomenological arguments in favor of asymmetric time evolution of micro-physical states are presented.

  13. Noncommutative Two Time Physics

    E-Print Network [OSTI]

    W. Chagas-Filho

    2006-05-10

    We present a classical formalism describing two-time physics with Abelian canonical gauge field backgrounds. The formalism can be used as a starting point for the construction of an interacting quantized two-time physics theory in a noncommutative soace-time.

  14. Time-periodic universes

    E-Print Network [OSTI]

    De-Xing Kong; Kefeng Liu; Ming Shen

    2008-08-30

    In this letter we construct a new time-periodic solution of the vacuum Einstein's field equations whose Riemann curvature norm takes the infinity at some points. We show that this solution is intrinsically time-periodic and describes a time-periodic universe with the "black hole". New physical phenomena are investigated and new singularities are analyzed for this universal model.

  15. Absolute Time Derivatives

    E-Print Network [OSTI]

    T. Matolcsi; P. Van

    2006-10-23

    A four dimensional treatment of nonrelativistic space-time gives a natural frame to deal with objective time derivatives. In this framework some well known objective time derivatives of continuum mechanics appear as Lie-derivatives. Their coordinatized forms depends on the tensorial properties of the relevant physical quantities. We calculate the particular forms of objective time derivatives for scalars, vectors, covectors and different second order tensors from the point of view of a rotating observer. The relation of substantial, material and objective time derivatives is treated.

  16. Time scales in LISA

    E-Print Network [OSTI]

    S. Pireaux

    2007-03-23

    The LISA mission is a space interferometer aiming at the detection of gravitational waves in the [$10^{-4}$,$10^{-1}$] Hz frequency band. In order to reach the gravitational wave detection level, a Time Delay Interferometry (TDI) method must be applied to get rid of (most of) the laser frequency noise and optical bench noise. This TDI analysis is carried out in terms of the coordinate time corresponding to the Barycentric Coordinate Reference System (BCRS), TCB, whereas the data at each of the three LISA stations is recorded in terms of each station proper time. We provide here the required proper time versus BCRS time transformation. We show that the difference in rate of station proper time versus TCB is of the order of $5 10^{-8}$. The difference between station proper times and TCB exhibits an oscillatory trend with a maximum amplitude of about $10^{-3}$ s.

  17. Time in Quantum Mechanics

    E-Print Network [OSTI]

    Curt A. Moyer

    2013-05-23

    The failure of conventional quantum theory to recognize time as an observable and to admit time operators is addressed. Instead of focusing on the existence of a time operator for a given Hamiltonian, we emphasize the role of the Hamiltonian as the generator of translations in time to construct time states. Taken together, these states constitute what we call a timeline, or quantum history, that is adequate for the representation of any physical state of the system. Such timelines appear to exist even for the semi-bounded and discrete Hamiltonian systems ruled out by Pauli's theorem. However, the step from a timeline to a valid time operator requires additional assumptions that are not always met. Still, this approach illuminates the crucial issue surrounding the construction of time operators, and establishes quantum histories as legitimate alternatives to the familiar coordinate and momentum bases of standard quantum theory.

  18. Oceanography | Vol.24, No.128 Ph i l i PPi N e S t r a it S Dy N a mi c S e x Pe r imeNt

    E-Print Network [OSTI]

    Sprintall, Janet

    Oceanography | Vol.24, No.128 Ph i l i PPi N e S t r a it S Dy N a mi c S e x Pe r imeNt Luzon Ocean Zoom of the 2008 sea surface height anomaly from Figure 3c. Oceanography | Vol.24, No.128 ThisarticlehasbeenpublishedinOceanography,Volume24,Number1,aquarterlyjournalofTheOceanographySociety.©2011byTheOceanography

  19. Photoelectron imaging and theoretical study on the structure and chemical binding of the mixed-ligand M(I) complexes, [HMSH]{sup ?} (M = Cu, Ag, and Au)

    SciTech Connect (OSTI)

    Qin, Zhengbo; Liu, Zhiling; Cong, Ran; Xie, Hua; Tang, Zichao, E-mail: zctang@dicp.ac.cn, E-mail: fanhj@dicp.ac.cn; Fan, Hongjun, E-mail: zctang@dicp.ac.cn, E-mail: fanhj@dicp.ac.cn [State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023 (China)] [State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023 (China)

    2014-03-21

    We have reported a combined photoelectron imaging and theoretical study on gaseous mixed-ligand M(I) complexes of [HMSH]{sup ?} (M = Cu, Ag, and Au). With the aid of Franck-Condon simulations, vibrationally resolved photoelectron spectra yield accurate electron affinities of 3.269(6), 3.669(10), and 3.591(6) eV for [HCuSH], [HAgSH], and [HAuSH], respectively. And low-frequency modes are observed: 368(12) cm{sup ?1} for [HCuSH], 286(12) cm{sup ?1} for [HAgSH], and 327(12) cm{sup ?1} for [HAuSH], respectively. Extensive theoretical calculations are performed to aid in the spectral assignments and the calculated values agree well with the experimental observations. Although the S and H atoms have little discrepancy in electronegativity (2.20 for H and 2.54 for S), distinct bonding properties are demonstrated between H–M and M–S bond. It is revealed that there exists significant ionic bonding between M–S in [HMSH]{sup ?} (M = Cu, Ag, and Au), while a gradual transition from ionic behavior between H–Cu in [HCuSH]{sup ?} to quite strong covalent bonding between H–Au in [HAuSH]{sup ?}, supported by a variety of chemical bonding analyses.

  20. Symmetry breaking in optimal timing of traffic signals on an idealized two-way street

    E-Print Network [OSTI]

    Panaggio, Mark J; Hu, Peiguang; Abrams, Daniel M

    2013-01-01

    Simple physical models based on fluid mechanics have long been used to understand the flow of vehicular traffic on freeways; analytically tractable models of flow on an urban grid, however, have not been as extensively explored. In an ideal world, traffic signals would be timed such that consecutive lights turned green just as vehicles arrived, eliminating the need to stop at each block. Unfortunately, this "green wave" scenario is generally unworkable due to frustration imposed by competing demands of traffic moving in different directions. Until now this has typically been resolved by numerical simulation and optimization. Here, we develop a theory for the flow in an idealized system consisting of a long two-way road with periodic intersections. We show that optimal signal timing can be understood analytically and that there are counter-intuitive asymmetric solutions to this signal coordination problem. We further explore how these theoretical solutions degrade as traffic conditions vary and automotive dens...

  1. Discrete-Time Pricing and Optimal Exercise of American Perpetual Warrants in the Geometric Random Walk Model

    SciTech Connect (OSTI)

    Vanderbei, Robert J., E-mail: rvdb@princeton.edu [Princeton University, Department of Operations Research and Financial Engineering (United States); P Latin-Small-Letter-Dotless-I nar, Mustafa C., E-mail: mustafap@bilkent.edu.tr [Bilkent University, Department of Industrial Engineering (Turkey); Bozkaya, Efe B. [Sabanc Latin-Small-Letter-Dotless-I University, Faculty of Administrative Sciences (Turkey)] [Sabanc Latin-Small-Letter-Dotless-I University, Faculty of Administrative Sciences (Turkey)

    2013-02-15

    An American option (or, warrant) is the right, but not the obligation, to purchase or sell an underlying equity at any time up to a predetermined expiration date for a predetermined amount. A perpetual American option differs from a plain American option in that it does not expire. In this study, we solve the optimal stopping problem of a perpetual American option (both call and put) in discrete time using linear programming duality. Under the assumption that the underlying stock price follows a discrete time and discrete state Markov process, namely a geometric random walk, we formulate the pricing problem as an infinite dimensional linear programming (LP) problem using the excessive-majorant property of the value function. This formulation allows us to solve complementary slackness conditions in closed-form, revealing an optimal stopping strategy which highlights the set of stock-prices where the option should be exercised. The analysis for the call option reveals that such a critical value exists only in some cases, depending on a combination of state-transition probabilities and the economic discount factor (i.e., the prevailing interest rate) whereas it ceases to be an issue for the put.

  2. Matter: Space without Time

    E-Print Network [OSTI]

    Yousef Ghazi-Tabatabai

    2012-11-19

    While Quantum Gravity remains elusive and Quantum Field Theory retains the interpretational difficulties of Quantum Mechanics, we have introduced an alternate approach to the unification of particles, fields, space and time, suggesting that the concept of matter as space without time provides a framework which unifies matter with spacetime and in which we anticipate the development of complete theories (ideally a single unified theory) describing observed 'particles, charges, fields and forces' solely with the geometry of our matter-space-time universe.

  3. Intrinsic Time Quantum Geometrodynamics

    E-Print Network [OSTI]

    Eyo Eyo Ita III; Chopin Soo; Hoi-Lai Yu

    2015-02-06

    Quantum Geometrodynamics with intrinsic time development and momentric variables is presented. An underlying SU(3) group structure at each spatial point regulates the theory. The intrinsic time behavior of the theory is analyzed, together with its ground state and primordial quantum fluctuations. Cotton-York potential dominates at early times when the universe was small; the ground state naturally resolves Penrose's Weyl Curvature Hypothesis, and thermodynamic and gravitational `arrows of time' point in the same direction. Ricci scalar potential corresponding to Einstein's General Relativity emerges as a zero-point energy contribution. A new set of fundamental commutation relations without Planck's constant emerges from the unification of Gravitation and Quantum Mechanics.

  4. Time functions as utilities

    E-Print Network [OSTI]

    E. Minguzzi

    2009-09-04

    Every time function on spacetime gives a (continuous) total preordering of the spacetime events which respects the notion of causal precedence. The problem of the existence of a (semi-)time function on spacetime and the problem of recovering the causal structure starting from the set of time functions are studied. It is pointed out that these problems have an analog in the field of microeconomics known as utility theory. In a chronological spacetime the semi-time functions correspond to the utilities for the chronological relation, while in a K-causal (stably causal) spacetime the time functions correspond to the utilities for the K^+ relation (Seifert's relation). By exploiting this analogy, we are able to import some mathematical results, most notably Peleg's and Levin's theorems, to the spacetime framework. As a consequence, we prove that a K-causal (i.e. stably causal) spacetime admits a time function and that the time or temporal functions can be used to recover the K^+ (or Seifert) relation which indeed turns out to be the intersection of the time or temporal orderings. This result tells us in which circumstances it is possible to recover the chronological or causal relation starting from the set of time or temporal functions allowed by the spacetime. Moreover, it is proved that a chronological spacetime in which the closure of the causal relation is transitive (for instance a reflective spacetime) admits a semi-time function. Along the way a new proof avoiding smoothing techniques is given that the existence of a time function implies stable causality, and a new short proof of the equivalence between K-causality and stable causality is given which takes advantage of Levin's theorem and smoothing techniques.

  5. Time Domain Reflectometry Theory

    E-Print Network [OSTI]

    Palermo, Sam

    Time Domain Reflectometry Theory Application Note 1304-2 For Use with Agilent 86100 Infiniium DCA #12;2 The most general approach to evaluating the time domain response of any electromagnetic system a concise presentation of the fundamentals of TDR and then relates these fundamentals to the parameters

  6. Search for decays of stopped long-lived particles produced in proton–proton collisions at ?s = 8 TeV

    E-Print Network [OSTI]

    Apyan, Aram

    A search has been performed for long-lived particles that could have come to rest within the CMS detector, using the time intervals between LHC beam crossings. The existence of such particles could be deduced from observation ...

  7. Kookie Thoughts: Imagining the United States Pavilion at Expo 67 (or How I Learned to Stop Worrying and Love the Bubble)

    E-Print Network [OSTI]

    Sheinin, Daniela

    2013-01-01

    subversive qualities of pop art and modern architecture. Onor think that Hollywood and pop art graphics . . . properlyArts Pavilion would focus for the first time on new talents—“figurists, abstract expressionists, new realists (pop),

  8. Stuart Stop Stuart Stop Stuart Stop Stuart Stop Stuart Stop Stuart Stop Stuart Stop Mon. to Fri. 9:37 AM 12:50 PM 4:30 PM Mon. to Wed. 1:15 AM 12:15 AM

    E-Print Network [OSTI]

    Huang, Jianyu

    , register 10:00am-10:30am Morning Session Break 3:00pm-3:30pm Afternoon Session Break 5:00pm-7:00pm Poster Session Break 3:00pm-3:30pm Afternoon Session Break 5:00pm-7:00pm Poster Session and Reception during

  9. Digital time delay

    DOE Patents [OSTI]

    Martin, A.D.

    1986-05-09

    Method and apparatus are provided for generating an output pulse following a trigger pulse at a time delay interval preset with a resolution which is high relative to a low resolution available from supplied clock pulses. A first lumped constant delay provides a first output signal at predetermined interpolation intervals corresponding to the desired high resolution time interval. Latching circuits latch the high resolution data to form a first synchronizing data set. A selected time interval has been preset to internal counters and corrected for circuit propagation delay times having the same order of magnitude as the desired high resolution. Internal system clock pulses count down the counters to generate an internal pulse delayed by an internal which is functionally related to the preset time interval. A second LCD corrects the internal signal with the high resolution time delay. A second internal pulse is then applied to a third LCD to generate a second set of synchronizing data which is complementary with the first set of synchronizing data for presentation to logic circuits. The logic circuits further delay the internal output signal with the internal pulses. The final delayed output signal thereafter enables the output pulse generator to produce the desired output pulse at the preset time delay interval following input of the trigger pulse.

  10. Neon time-of-flight backscattering spectrometry for surface analysis 

    E-Print Network [OSTI]

    Garcia, Richard Michael

    2001-01-01

    the observed system resolutions with those obtained previously in similar analyses. Discriminator thresholds, electronic start/stop logic, aperture sizes, target tilt and beam energies were varied and studied to determine their effect on system resolution...

  11. Identification of proteins capable of metal reduction from the proteome of the Gram-positive bacterium Desulfotomaculum reducens MI-1 using an NADH-based activity assay

    SciTech Connect (OSTI)

    Otwell, Annie E.; Sherwood, Roberts; Zhang, Sheng; Nelson, Ornella D.; Li, Zhi; Lin, Hening; Callister, Stephen J.; Richardson, Ruth E.

    2015-01-01

    Metal reduction capability has been found in numerous species of environmentally abundant Gram-positive bacteria. However, understanding of microbial metal reduction is based almost solely on studies of Gram-negative organisms. In this study, we focus on Desulfotomaculum reducens MI-1, a Gram-positive metal reducer whose genome lacks genes with similarity to any characterized metal reductase. D. reducens has been shown to reduce not only Fe(III), but also the environmentally important contaminants U(VI) and Cr(VI). By extracting, separating, and analyzing the functional proteome of D. reducens, using a ferrozine-based assay in order to screen for chelated Fe(III)-NTA reduction with NADH as electron donor, we have identified proteins not previously characterized as iron reductases. Their function was confirmed by heterologous expression in E. coli. These are the protein NADH:flavin oxidoreductase (Dred_2421) and a protein complex composed of oxidoreductase FAD/NAD(P)-binding subunit (Dred_1685) and dihydroorotate dehydrogenase 1B (Dred_1686). Dred_2421 was identified in the soluble proteome and is predicted to be a cytoplasmic protein. Dred_1685 and Dred_1686 were identified in both the soluble as well as the insoluble (presumably membrane) protein fraction, suggesting a type of membrane-association, although PSORTb predicts both proteins are cytoplasmic. Furthermore, we show that these proteins have the capability to reduce soluble Cr(VI) and U(VI) with NADH as electron donor. This study is the first functional proteomic analysis of D. reducens, and one of the first analyses of metal and radionuclide reduction in an environmentally relevant Gram-positive bacterium.

  12. Kairoscope : coordinating time socially

    E-Print Network [OSTI]

    Martin, Reed Eric

    2010-01-01

    If everyone says time is relative, why is it still so rigidly defined? There have been many attempts to address the issue of coordinating schedules, but each of these attempts runs into an issue of rigidity: in order to ...

  13. The Williston time capsule

    E-Print Network [OSTI]

    Moses, David (David Patrick)

    2015-01-01

    This project is a time capsule of the oil economy, created by entombing everyday objects made from and powered by petroleum into a landscape that spatially recreates the processes of drilling and fracking a contemporary ...

  14. Sublinear Time Algorithms

    E-Print Network [OSTI]

    Rubinfeld, Ronitt

    Sublinear time algorithms represent a new paradigm in computing, where an algorithm must give some sort of an answer after inspecting only a very small portion of the input. We discuss the types of answers that one can ...

  15. Time, energy & form

    E-Print Network [OSTI]

    McInnis, Martha Jane

    1982-01-01

    Physical manifestations of time occur in natural forms of all sizes. Architectural form serves as shelter while providing a built envelope of human life, simultaneously influencing and influenced by energetic activities ...

  16. Drug Retention Times

    SciTech Connect (OSTI)

    Center for Human Reliability Studies

    2007-05-01

    The purpose of this monograph is to provide information on drug retention times in the human body. The information provided is based on plausible illegal drug use activities that might be engaged in by a recreational drug user

  17. Drug Retention Times

    SciTech Connect (OSTI)

    Center for Human Reliability Studies

    2007-05-01

    The purpose of this monograph is to provide information on drug retention times in the human body. The information provided is based on plausible illegal drug use activities that might be engaged in by a recreational drug user.

  18. Time in quantum mechanics 

    E-Print Network [OSTI]

    Chapin, Kimberly R.

    1997-01-01

    TIME IN QUANTUM MECHANICS A Thesis by KIMBERLY R. CHAPIN Submitted to Texas A8M University in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE Approved as to style and content by: Marian O. Scully (Chair... of Committee) Edward S. Fry (Member) aan Laane (Member) Thomas W. Adair, III (Head of Department) August 1997 Major Subject: Physics TIME IN QIJANTUM MECHANICS A Thesis by KIMBERLY R. CHAPIN Submitted to the Oflice of Graduate Studies of Texas A...

  19. The thermodynamics of time

    E-Print Network [OSTI]

    Dries Sels; Michiel Wouters

    2015-01-22

    The problem of time is a deep paradox in our physical description of the world. According to Aristotle's relational theory, time is a measure of change and does not exist on its own. In contrast, quantum mechanics, just like Newtonian mechanics, is equipped with a master clock that dictates the evolution of a system. This clock is infinitely precise and tacitly supplied free of charge from outside physics. Not only does this absolute time make it notoriously difficult to make a consistent theory of quantum gravity, it is also the underlying problem in establishing the second law. Indeed, contrary to our experience, the Wheeler-deWitt equation --a canonical quantization of general relativity-- predicts a static universe. Similarly, when simply concerned with the dynamics of a closed quantum system, there is no second law because the Von Neumann entropy is invariant under unitary transformations. Here we are mainly concerned with the latter problem and we show that it can be resolved by attributing a minimal amount of resources to the measurement of time. Although there is an absolute time in quantum mechanics, an observer can only establish a time by measuring a clock. For a local measurement, the minimal entropy production is equal to the number of ticks. This lower bound is attained by a black hole.

  20. Time and Labor 9.1 Time Keeper Payroll -HCSD

    E-Print Network [OSTI]

    Time and Labor 9.1 Time Keeper Payroll - HCSD Version Date: July 2012 #12;COPYRIGHT & TRADEMARKS create a risk of personal injury. If you use this software in dangerous applications, then you shall Guide Time and Labor 9.1 Time Keeper Payroll - HCSD Page iii Table of Contents Time and Labor 9.1 Time

  1. Timed Alternating-Time Temporal Logic Thomas A. Henzinger1

    E-Print Network [OSTI]

    Henzinger, Thomas A.

    equally powerful options for updating the state of the game, advancing time, or blocking time. Second, we in order to specify real-time objectives for games played on timed structures. We define the semantics Timed games are a formal model for the synthesis of real-time systems [22, 20]. While much research

  2. Time-Resolved

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefieldSulfateSciTechtail.Theory ofDidDevelopment TopMetathesisSediments andTheTime-Resolved Time-Resolved

  3. EM PREPARATION OF TISSUES THAT CONTAIN ELASTIC FIBERS (3 stopping points are listed = places that you can leave the tissue overnight)

    E-Print Network [OSTI]

    Mecham, Robert

    % uranyl acetate in dH2O for 1 hr at 4°C wash: 1 x 5 min in dH2O 8. DEHYDRATE: 8 min each in 10, 25, 40, 55 tetroxide; or 2) cacodylate buffer in contact with uranyl acetate - WASH WELL. CAUTION: · osmium tetroxide% uranyl acetate in absolute methanol (filtered) for 2 minutes · Wash by dipping 20 - 30 times in 3

  4. Time Activity Time Activity Time Activity Tuesday CLOSED CONFERENCE CLOSED CONFERENCE CLOSED CONFERENCE

    E-Print Network [OSTI]

    Burg, Theresa

    Time Activity Time Activity Time Activity Tuesday CLOSED CONFERENCE CLOSED CONFERENCE CLOSED CONFERENCE 2-Jun-15 Wednesday CLOSED CONFERENCE CLOSED CONFERENCE CLOSED CONFERENCE 3-Jun-15 Thursday CLOSED

  5. Time in Cosmology

    E-Print Network [OSTI]

    R. Brout; R. Parentani

    1999-02-05

    The notion of time in cosmology is revealed through an examination of transition matrix elements of radiative processes occurring in the cosmos. To begin with, the very concept of time is delineated in classical physics in terms of correlations between the succession of configurations which describe a process and a standard trajectory called the clock. The total is an isolated system of fixed energy. This is relevant for cosmology in that the universe is an isolated system which we take to be homogeneous and isotropic. Furthermore, in virtue of the constraint which arises from reparametrization invariance of time, it has total energy zero. Therefore the momentum of the scale factor is determined from the energy of matter. In the quantum theory this is exploited through use of the WKB approximation for the wave function of the scale factor, justified for a large universe. The formalism then gives rise to matrix elements describing matter processes. These are shown to take on the form of usual time dependent quantum amplitudes wherein the temporal dependence is given by a background which is once more fixed by the total energy of matter.

  6. Time and Attendance Reporting

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2004-10-22

    DOE O 535.1 establishes the Department's requirements and responsibilities governing time and attendance reporting. The purpose of this revision is to reflect the transition of payroll processing from the Capital Accounting Center to the Defense Finance and Accounting System. Cancels DOE O 3600.1B. Canceled by DOE O 322.1C.

  7. Presenter:! Time & Date: !

    E-Print Network [OSTI]

    Collar, Juan I.

    a checkbook, you can understand which energy options have the promise of supporting humankind - wind, hydro://cfcpwork.uchicago.edu/mailman/listinfo/cafe! A Reality Check on Alternative Energy! #12;A Reality Check on Alternative Energy! Presenter: Liz Moyer! Time a bigger, richer population without fossil fuels (which will definitely run out someday)? Energy is a hot

  8. Time-Encoded Imagers.

    SciTech Connect (OSTI)

    Marleau, Peter; Brubaker, Erik

    2014-11-01

    This report provides a short overview of the DNN R&D funded project, Time-Encoded Imagers. The project began in FY11 and concluded in FY14. The Project Description below provides the overall motivation and objectives for the project as well as a summary of programmatic direction. It is followed by a short description of each task and the resulting deliverables.

  9. Time reversal communication system

    DOE Patents [OSTI]

    Candy, James V. (Danville, CA); Meyer, Alan W. (Danville, CA)

    2008-12-02

    A system of transmitting a signal through a channel medium comprises digitizing the signal, time-reversing the digitized signal, and transmitting the signal through the channel medium. The channel medium may be air, earth, water, tissue, metal, and/or non-metal.

  10. Daimler Chrysler Auburn Hills, MI

    E-Print Network [OSTI]

    Papalambros, Panos

    Sponsored by: Automotive Research Center National Automotive Center (NAC) U.S. Army Tank Automotive Research, Development and Engineering Center (TARDEC) U.S. Army Tank-Automotive and Armaments Command (TACOM in ground vehicle simulation. It will present the results of ARC research to university, industry

  11. US ENC MI Site Consumption

    Gasoline and Diesel Fuel Update (EIA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustments (Billion Cubic Feet) Wyoming963 1.969 1.979Coal Consumers inYear JanSales Type: Sales

  12. Tevatron injection timing

    SciTech Connect (OSTI)

    Saritepe, S.; Annala, G.

    1993-06-01

    Bunched beam transfer from one accelerator to another requires coordination and synchronization of many ramped devices. During collider operation timing issues are more complicated since one has to switch from proton injection devices to antiproton injection devices. Proton and antiproton transfers are clearly distinct sequences since protons and antiprotons circulate in opposite directions in the Main Ring (MR) and in the Tevatron. The time bumps are different, the kicker firing delays are different, the kickers and lambertson magnets are different, etc. Antiprotons are too precious to be used for tuning purposes, therefore protons are transferred from the Tevatron back into the Main Ring, tracing the path of antiprotons backwards. This tuning operation is called ``reverse injection.`` Previously, the reverse injection was handled in one supercycle. One batch of uncoalesced bunches was injected into the Tevatron and ejected after 40 seconds. Then the orbit closure was performed in the MR. In the new scheme the lambertson magnets have to be moved and separator polarities have to be switched, activities that cannot be completed in one supercycle. Therefore, the reverse injection sequence was changed. This involved the redefinition of TVBS clock event $D8 as MRBS $D8 thus making it possible to inject 6 proton batches (or coalesced bunches) and eject them one at a time on command, performing orbit closure each time in the MR. Injection devices are clock event driven. The TCLK is used as the reference clock. Certain TCLK events are triggered by the MR beam synchronized clock (MRBS) events. Some delays are measured in terms of MRBS ticks and MR revolutions. See Appendix A for a brief description of the beam synchronized clocks.

  13. Time Reversal Violation

    SciTech Connect (OSTI)

    Quinn, H; /SLAC

    2009-01-27

    This talk briefly reviews three types of time-asymmetry in physics, which I classify as universal, macroscopic and microscopic. Most of the talk is focused on the latter, namely the violation of T-reversal invariance in particle physics theories. In sum tests of microscopic T-invariance, or observations of its violation, are limited by the fact that, while we can measure many processes, only in very few cases can we construct a matched pair of process and inverse process and observe it with sufficient sensitivity to make a test. In both the cases discussed here we can achieve an observable T violation making use of flavor tagging, and in the second case also using the quantum properties of an antisymmetric coherent state of two B mesons to construct a CP-tag. Both these tagging properties depend only on very general properties of the flavor and/or CP quantum numbers and so provide model independent tests for T-invariance violations. The microscopic laws of physics are very close to T-symmetric. There are small effects that give CP- and T-violating processes in three-generation-probing weak decays. Where a T-violating observable can be constructed we see the relationships between T-violation and CP-violation expected in a CPT conserving theory. These microscopic effects are unrelated to the 'arrow of time' that is defined by increasing entropy, or in the time direction defined by the expansion of our Universe.

  14. On-chip single-copy real-time reverse-transcription PCR in isolated picoliter droplets

    SciTech Connect (OSTI)

    Beer, N R; Wheeler, E; Lee-Houghton, L; Watkins, N; Nasarabadi, S; Hebert, N; Leung, P; Arnold, D; Bailey, C; Colston, B

    2007-12-19

    The first lab-on-chip system for picoliter droplet generation and RNA isolation, followed by reverse transcription, and PCR amplification with real-time fluorescence detection in the trapped droplets has been developed. The system utilized a shearing T-junction in a fused silica device to generate a stream of monodisperse picoliter-scale droplets that were isolated from the microfluidic channel walls and each other by the oil phase carrier. An off-chip valving system stopped the droplets on-chip, allowing thermal cycling for reverse transcription and subsequent PCR amplification without droplet motion. This combination of the established real-time reverse transcription-PCR assay with digital microfluidics is ideal for isolating single-copy RNA and virions from a complex environment, and will be useful in viral discovery and gene-profiling applications.

  15. Space-time diamonds

    E-Print Network [OSTI]

    Daiqin Su; T. C. Ralph

    2015-07-02

    We show that the particle number distribution of diamond modes, modes that are localised in a finite space-time region, are thermal for the Minkowski vacuum state of a massless scalar field, an analogue to the Unruh effect. The temperature of the diamond is inversely proportional to its size. An inertial observer can detect this thermal radiation by coupling to the diamond modes using an appropriate energy scaled detector. We further investigate the correlations between various diamonds and find that entanglement between adjacent diamonds dominates.

  16. On-chip real-time single-copy polymerase chain reaction in picoliter droplets

    SciTech Connect (OSTI)

    Beer, N R; Hindson, B; Wheeler, E; Hall, S B; Rose, K A; Kennedy, I; Colston, B

    2007-04-20

    The first lab-on-chip system for picoliter droplet generation and PCR amplification with real-time fluorescence detection has performed PCR in isolated droplets at volumes 10{sup 6} smaller than commercial real-time PCR systems. The system utilized a shearing T-junction in a silicon device to generate a stream of monodisperse picoliter droplets that were isolated from the microfluidic channel walls and each other by the oil phase carrier. An off-chip valving system stopped the droplets on-chip, allowing them to be thermal cycled through the PCR protocol without droplet motion. With this system a 10-pL droplet, encapsulating less than one copy of viral genomic DNA through Poisson statistics, showed real-time PCR amplification curves with a cycle threshold of {approx}18, twenty cycles earlier than commercial instruments. This combination of the established real-time PCR assay with digital microfluidics is ideal for isolating single-copy nucleic acids in a complex environment.

  17. Time Valid One-Time Signature for Time-Critical Multicast Data Authentication

    E-Print Network [OSTI]

    Nahrstedt, Klara

    malicious attacks. In this paper, we propose a novel signature model ­ Time Valid One-Time Signature (TVTime Valid One-Time Signature for Time-Critical Multicast Data Authentication Qiyan Wang, Himanshu-OTS) ­ to boost the efficiency of regular one-time signature schemes. Based on the TV-OTS model, we design

  18. Advertising Emergency Department Wait Times

    E-Print Network [OSTI]

    Weiner, Scott G

    2013-01-01

    studies evaluating the advertising of ED wait times. Only 1potentially used for advertising may be inaccurate. AccessedE ditorial Advertising Emergency Department Wait Times Scott

  19. Final Exam Location and Time

    E-Print Network [OSTI]

    Final Exam Location and Time. Math 162 Fall 2001. Date: Wednesday December 12, 2001. Time: 7:00 pm -9:00 pm. Location: Lambert Fieldhouse ...

  20. Final Exam Location and Time

    E-Print Network [OSTI]

    Final Exam Location and Time. Math 161 Fall 2001. Date: Friday December 14, 2001. Time: 8:00 am -10:00 am. Location: Lambert Fieldhouse ...

  1. 1. 2 , 4 2 ( Times

    E-Print Network [OSTI]

    Kaplan, Alexander

    format with double line spacing (font Times New Roman, 12 pt; margins: left and up -- 30 mm, right , . 20. , , . 1. 2 , 4 2 ( Times New Roman, 12 pt

  2. Denoising Deterministic Time Series

    E-Print Network [OSTI]

    Steven P. Lalley; Andrew B. Nobel

    2006-04-21

    This paper is concerned with the problem of recovering a finite, deterministic time series from observations that are corrupted by additive, independent noise. A distinctive feature of this problem is that the available data exhibit long-range dependence and, as a consequence, existing statistical theory and methods are not readily applicable. This paper gives an analysis of the denoising problem that extends recent work of Lalley, but begins from first principles. Both positive and negative results are established. The positive results show that denoising is possible under somewhat restrictive conditions on the additive noise. The negative results show that, under more general conditions on the noise, no procedure can recover the underlying deterministic series.

  3. Real time automated inspection

    DOE Patents [OSTI]

    Fant, K.M.; Fundakowski, R.A.; Levitt, T.S.; Overland, J.E.; Suresh, B.R.; Ulrich, F.W.

    1985-05-21

    A method and apparatus are described relating to the real time automatic detection and classification of characteristic type surface imperfections occurring on the surfaces of material of interest such as moving hot metal slabs produced by a continuous steel caster. A data camera transversely scans continuous lines of such a surface to sense light intensities of scanned pixels and generates corresponding voltage values. The voltage values are converted to corresponding digital values to form a digital image of the surface which is subsequently processed to form an edge-enhanced image having scan lines characterized by intervals corresponding to the edges of the image. The edge-enhanced image is thresholded to segment out the edges and objects formed by the edges by interval matching and bin tracking. Features of the objects are derived and such features are utilized to classify the objects into characteristic type surface imperfections. 43 figs.

  4. Time encoded radiation imaging

    DOE Patents [OSTI]

    Marleau, Peter; Brubaker, Erik; Kiff, Scott

    2014-10-21

    The various technologies presented herein relate to detecting nuclear material at a large stand-off distance. An imaging system is presented which can detect nuclear material by utilizing time encoded imaging relating to maximum and minimum radiation particle counts rates. The imaging system is integrated with a data acquisition system that can utilize variations in photon pulse shape to discriminate between neutron and gamma-ray interactions. Modulation in the detected neutron count rates as a function of the angular orientation of the detector due to attenuation of neighboring detectors is utilized to reconstruct the neutron source distribution over 360 degrees around the imaging system. Neutrons (e.g., fast neutrons) and/or gamma-rays are incident upon scintillation material in the imager, the photons generated by the scintillation material are converted to electrical energy from which the respective neutrons/gamma rays can be determined and, accordingly, a direction to, and the location of, a radiation source identified.

  5. Time's Ontic Voltage Craig Callender

    E-Print Network [OSTI]

    Callender, Craig

    Time's Ontic Voltage Craig Callender Philosophy of time, as practiced throughout the last hundred venue for attacking questions about the nature of time--in sharp contrast to the primary venue slowly in philosophy of time.1 Since twentieth-century analytic philosophy as a whole often drew

  6. Untameable Timed Automata! (Extended Abstract)

    E-Print Network [OSTI]

    Doyen, Laurent

    are a widely studied model for real­time systems. Since 8 years, several tools implement this model­life systems. 1 Introduction Real­Time Systems ­ Since their introduction by Alur and Dill in [AD94], timed au­ tomata are one of the most studied models for real­time systems. Numerous works have been devoted

  7. Untameable Timed Automata! (Extended Abstract)

    E-Print Network [OSTI]

    Doyen, Laurent

    model for real-time systems. Since 8 years, several tools implement this model and are successfully used for a restricted class of timed automata, which has been sufficient for modeling numerous real-life systems. 1 Introduction Real-Time Systems - Since their introduction by Alur and Dill in [AD94], timed au- tomata are one

  8. A study of the composition of soap stock from cottonseed oil as influenced by variation in the length of time of cooking cotton-seed meats 

    E-Print Network [OSTI]

    Siecke, Paul

    1932-01-01

    effect of temperature, time? an4 rate of heating cn the quality of cakes and the refining loss of the oil Eads (1) states Chat, "In oocking at high temperatures, the length of time in cooking should be less than fifty minutes. " Ls shown by Caldwell.... 839 s4. 685c 6 6OI st3e590 C3e480C 6+821 ss2. 68'7 c2. 608C 7. 3O6 Length of Cook vs. Yield ano anality of Oil 40 'oe 550 o 520 g z10 00 0;. 90 -15 220 250 "80 20 215 22 2 0 225 ]. 0 0 9 b( 8 215 40 60 Length o" Cook in Mi utes...

  9. SLH Timing Belt Powertrain

    SciTech Connect (OSTI)

    Schneider, Abe

    2014-04-09

    The main goal of this proposal was to develop and test a novel powertrain solution for the SLH hydroEngine?, a low-cost, efficient low-head hydropower technology. Nearly two-thirds of U.S. renewable electricity is produced by hydropower (EIA 2010). According to the U.S. Department of Energy; this amount could be increased by 50% with small hydropower plants, often using already-existing dams (Hall 2004). There are more than 80,000 existing dams, and of these, less than 4% generate power (Blankinship 2009). In addition, there are over 800 irrigation districts in the U.S., many with multiple, non-power, low-head drops. These existing, non-power dams and irrigation drops could be retrofitted to produce distributed, baseload, renewable energy with appropriate technology. The problem is that most existing dams are low-head, or less than 30 feet in height (Ragon 2009). Only about 2% of the available low-head hydropower resource in the U.S. has been developed, leaving more than 70 GW of annual mean potential low-head capacity untapped (Hall 2004). Natel Energy, Inc. is developing a low-head hydropower turbine that operates efficiently at heads less than 6 meters and is cost-effective for deployment across multiple low-head structures. Because of the unique racetrack-like path taken by the prime-movers in the SLH, a flexible powertrain is required. Historically, the only viable technological solution was roller chain. Despite the having the ability to easily attach blades, roller chain is characterized by significant drawbacks, including high cost, wear, and vibration from chordal action. Advanced carbon-#12;fiber-reinforced timing belts have been recently developed which, coupled with a novel belt attachment system developed by Natel Energy, result in a large reduction in moving parts, reduced mass and cost, and elimination of chordal action for increased fatigue life. The work done in this project affirmatively addressed each of the following 3 major uncertainties concerning a timing-belt based hydroEngine ?powertrain: 1. Can a belt handle the high torques and power loads demanded by the SLH? (Yes.) 2. Can the SLH blades be mounted to belt with a connection that can withstand the loads encountered in operation? (Yes.) 3. Can the belt, with blade attachments, live through the required cyclic loading? (Yes.) The research adds to the general understanding of sustainable small hydropower systems by using innovative system testing to develop and demonstrate performance of a novel powertrain solution, enabling a new type of hydroelectric turbine to be commercially developed. The technical effectiveness of the methods investigated has been shown to be positive through an extensive design and testing process accommodating many constraints and goals, with a major emphasis on high cycle fatigue life. Economic feasibility of the innovations has been demonstrated through many iterations of design for manufacturability and cost reduction. The project is of benefit to the public because it has helped to develop a solution to a major problem -- despite the large available potential for new low-head hydropower, high capital costs and high levelized cost of electricity (LCOE) continue to be major barriers to project development. The hydroEngine? represents a significant innovation, leveraging novel fluid mechanics and mechanical configuration to allow lower-cost turbine manufacture and development of low head hydropower resources.

  10. Dead-time optimized time-correlated photon counting instrument with synchronized, independent timing channels

    E-Print Network [OSTI]

    Enderlein, Jörg

    Dead-time optimized time-correlated photon counting instrument with synchronized, independent timing channels Michael Wahla and Hans-Jürgen Rahn PicoQuant GmbH, Rudower Chaussee 29, D-12489 Berlin December 2006; accepted 19 February 2007; published online 23 March 2007 Time-correlated single photon

  11. Time and Labor 9.1 Time Keeper -HCSD

    E-Print Network [OSTI]

    Time and Labor 9.1 Time Keeper - HCSD Version Date: July 2012 #12;COPYRIGHT & TRADEMARKS Copyright create a risk of personal injury. If you use this software in dangerous applications, then you shall

  12. Maximizing the Efficiency of LHC Maintenance during Operation Times using a Mobile Tool

    E-Print Network [OSTI]

    Martel, Pedro; Mallon Amerigo, Sonia; Pater, Lukasz; Petit, Stephan; Widegren, David

    2010-01-01

    The operation of the Large Hadron Collider (LHC) imposes minimum maintenance time, when needed corrections to all systems are to be carried out. Today's maintenance management tools at CERN are seen as too slow and cumbersome for such a challenge. The short duration of the technical stops (72 h/month) requires preparation of jobs in advance, and coordination of all involved teams; at the same time, the radio-protection of personnel in the LHC underground areas imposes a strict "As Low As Reasonably Achievable"(ALARA) policy for the works' duration. In order to perform a maximum of tasks in a short time, a mobile tool for the manipulation of job and equipment data has been created. The ability to signal a new job to a team in the field will avoid unnecessary trips to the tunnel; the signalling of a job's completion (and its details) will allow subsequent jobs to start promptly and with more information; finally, the possibility to consult equipment's full manufacturing and installation data "in situ" will help...

  13. 323. 1JYNJ;MI(S AND 00!ANTIM3 CF OOGINIC rouJJI'ANl' lNll'RICITrns (}l GAY MINERAlS. Z.Z. 2'bang. Penchu 2'bang and D.L. Sjmks. l:epart:lrent of Plant and Soil Sciences.

    E-Print Network [OSTI]

    Sparks, Donald L.

    323. 1JYNJ;MI(S AND 00!ANTIM3 CF OOGINIC rouJJI'ANl' lNll'RICITrns (}l GAY MINERAlS. Z.Z. 2'bangI.ark. IE 19717-lm The interactions of clay minerals with organic pollutants .ere investigated using

  14. Date of Injury Date Time In Time Out

    E-Print Network [OSTI]

    : NORMAL Work Schedule (ie: MF, 8am5pm)First Name Last Name # of hours missed from work #12;RISK MGTDate of Injury Date Time In Time Out Total time worked medical appt no work within restrictions Next Medical Appointment(s): Tuesday of each week. Risk Mgt email: workcomp@colostate.edu; fax

  15. A Web-Based Common Framework to Support the Test and Evaluation Process Any Time, Anywhere, and Anyhow

    SciTech Connect (OSTI)

    Schur, Anne ); Brown, James C. ); Eaton, Sharon L. ); Gibson, Alex G. ); Scott, Ryan T. ); Tanasse, Ted E. )

    2001-01-01

    Test and evaluation (T and E) is an enterprise. For any product, large or small, performance data is desired on many aspects to evaluate the product?s effectiveness for the intended users. Representing the many T and E facets without bewildering the user is challenging when there is a range of people, from the system developers to the manager of the organization, that want specific feedback. A web-based One-Stop Evaluation Center was created to meet these needs for a particular project. The evaluation center is usable at any time in the systems development lifecycle and streamlines the T and E enterprise. This paper discusses a common framework that unifies the T and E process with many stakeholders involved and is flexible to accommodate each stakeholders?specific evaluative processes and content. Our success has translated to many cost savings by enabling quick responses to change and a better line of communication between the users, developers, and managers.

  16. Lu1-xI3:Cex--A Scintillator for gamma ray spectroscopy and time-of-flight PET

    DOE Patents [OSTI]

    Shah, Kanai S. (Newton, MA)

    2009-03-17

    The present invention concerns very fast scintillator materials comprising lutetium iodide doped with Cerium Lu.sub.1-xI.sub.3:Ce.sub.x; LuI.sub.3:Ce). The LuI.sub.3 scintillator material has surprisingly good characteristics including high light output, high gamma ray stopping efficiency, fast response, low cost, good proportionality, and minimal afterglow that the material is useful for gamma ray spectroscopy, medical imaging, nuclear and high energy physics research, diffraction, non-destructive testing, nuclear treaty verification and safeguards, and geological exploration. The timing resolution of the scintillators of the present invention provide compositions capable of resolving the position of an annihilation event within a portion of a human body cross-section.

  17. Time translation of quantum properties

    E-Print Network [OSTI]

    L. Vanni; R. Laura

    2008-12-03

    Based on the notion of time translation, we develop a formalism to deal with the logic of quantum properties at different times. In our formalism it is possible to enlarge the usual notion of context to include composed properties involving properties at different times. We compare our results with the theory of consistent histories.

  18. Time machines and quantum theory

    E-Print Network [OSTI]

    Mark J Hadley

    2006-12-02

    There is a deep structural link between acausal spacetimes and quantum theory. As a consequence quantum theory may resolve some "paradoxes" of time travel. Conversely, non-time-orientable spacetimes naturally give rise to electric charges and spin half. If an explanation of quantum theory is possible, then general relativity with time travel could be it.

  19. BIOENERGIZEME INFOGRAPHIC CHALLENGE: Powering the World One Poop at a Time

    Broader source: Energy.gov [DOE]

    This infographic was created by students from Genesee Career Institute in Flint, MI, as part of the U.S. Department of Energy-BioenergizeME Infographic Challenge. The BioenergizeME Infographic...

  20. The LCLS Timing Event System

    SciTech Connect (OSTI)

    Dusatko, John; Allison, S.; Browne, M.; Krejcik, P.; /SLAC

    2012-07-23

    The Linac Coherent Light Source requires precision timing trigger signals for various accelerator diagnostics and controls at SLAC-NAL. A new timing system has been developed that meets these requirements. This system is based on COTS hardware with a mixture of custom-designed units. An added challenge has been the requirement that the LCLS Timing System must co-exist and 'know' about the existing SLC Timing System. This paper describes the architecture, construction and performance of the LCLS timing event system.

  1. Setting and Maintaining Arecibo Observatory's Timing Systems

    E-Print Network [OSTI]

    Frequency Standard 14 Time Code Generators TRAK Synchronized Time Code Generator 38 EECO Time Code Generator the time codes if the TRAC Synchronized Time Code Generator fails. Soon the TrueTime time code generator) Time Code Generator TRAK Synchronized Time Code Generator EECO Time Code Generator Transfer standard

  2. A COMPREHENSIVE, ONE-STOP REFERENCE

    E-Print Network [OSTI]

    Sharma, Gaurav

    A volume in the Electrical Engineering & Applied Signal Processing series Series Editor: Alexander PRESS #12;Ordering Information: Orders must be prepaid or accompanied by a purchase order. Checks should

  3. The Machine Stops by E. M. Forster

    E-Print Network [OSTI]

    Vetter, Frederick J.

    1909 1 The Air-Ship Imagine, if you can, a small room, hexagonal in shape, like the cell of a bee for a visit. "The air-ship barely takes two days to fly between me and you." "I dislike air-ships." "Why?" "I in an air-ship." "I do not get them anywhere else." "What kind of ideas can the air give you?" He paused

  4. Stopping Illicit Procurement: Lessons from Global Finance

    SciTech Connect (OSTI)

    Hund, Gretchen; Kurzrok, Andrew J.

    2014-06-19

    Government regulators and the financial sector cooperate to combat money laundering and terrorist financing. This information-sharing relationship is built upon a strong legislative foundation and effective operational procedures. As with money-laundering and terrorist financing, halting the illicit procurement of dual-use commodities requires close coordination between government and industry. However, many of the legal and operational features present in financial threat cooperation do not exist in the export control realm. This article analyzes the applicability of financial industry cooperative measures to nonproliferation.

  5. Quantum mechanics: last stop for reductionism

    E-Print Network [OSTI]

    Gabriele Carcassi

    2012-03-16

    The state space of a homogeneous body is derived under two different assumptions: infinitesimal reducibility and irreducibility. The first assumption leads to a real vector space, used in classical mechanics, while the second one leads to a complex vector space, used in quantum mechanics.

  6. Has the person collapsed or stopped breathing?

    E-Print Network [OSTI]

    Oliver, Douglas L.

    -800-222-1222. CONNECTICUT POISON CONTROL CENTER University of Connecticut Health Center · 24 Hours a Day · Free precautions. Install carbon monoxide alarms. CONNECTICUT POISON CONTROL CENTER #12;

  7. Stop Playing Favorites with the Tax Code 

    E-Print Network [OSTI]

    Taylor, Lori L.

    2011-01-01

    The Great Recession has punched a gaping hole in state government budgets. California has a projected budget deficit of $21.3 billion for the 2012 fiscal year. Illinois has a projected shortfall of $17 billion; New ...

  8. Production and perception of glottal stops

    E-Print Network [OSTI]

    Garellek, Marc

    2013-01-01

    v Production studies . . . . . . . . . . . .aerodynamic theory of voice production. Journal of SpeechFrazier, M. ( 2009). The production and perception of pitch

  9. HOW PEOPLE STOP SMOKING: AN EXPLORATORY STUDY

    E-Print Network [OSTI]

    Wax, Rosalie H.

    1978-04-01

    .system: predisposing toward coughs, aggravating colds and infections, curtailing endurance and decreasing stamina. About half of our sample related their decision to quit to an event or circumstance not directly related to their .immediate condition... was helped by going on a field trip to a country where cigarettes were scarce. "I lived down there for two years and had a new style of life." 5 Mid-American Review of Sociology For several respondents, the process was cumulative: I had smoker's cough, and my...

  10. NREL: Transportation Research - Truck Stop Electrification Testing

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration wouldMass map shines lightGeospatial ToolkitSMARTSWorking WithSuccessTransportationTruckTruck

  11. Quality Procedure - Stop Work | Department of Energy

    Energy Savers [EERE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematicsEnergyInterested PartiesBuildingBudget || DepartmentPuttingRecords Management Quality

  12. Labs Race to Stop Iran"

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverseIMPACTThousand CubicResourcelogo and masthead BerkeleySiteSeason of

  13. Mobile Truck Stop Electrification Site Locator

    Alternative Fuels and Advanced Vehicles Data Center [Office of Energy Efficiency and Renewable Energy (EERE)]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels Data Center Home Page onPropane Rolls on

  14. Local-time effect on small space-time scale

    E-Print Network [OSTI]

    V. A. Panchelyuga; V. A. Kolombet; M. S. Panchelyuga; S. E. Shnoll

    2006-10-18

    The paper presents an investigation of local-time effect - one of the manifestations of macroscopic fluctuations phenomena. Was shown the existence of the named effect for longitudinal distance between locations of measurements up to 500 meters. Also a structure of intervals distribution in neighborhood of local-time peak was studied and splitting of the peak was found out. Obtained results lead to conclusion about sharp anisotropy of space-time.

  15. On the Flow of Time

    E-Print Network [OSTI]

    George F R Ellis

    2008-12-01

    Current theoretical physics suggests the flow of time is an illusion: the entire universe just is, with no special meaning attached to the present time. This paper points out that this view, in essence represented by usual space-time diagrams, is based on time-reversible microphysical laws, which fail to capture essential features of the time-irreversible nature of decoherence and the quantum measurement process, as well as macro-physical behaviour and the development of emergent complex systems, including life, which exist in the real universe. When these are taken into account, the unchanging block universe view of spacetime is best replaced by an evolving block universe which extends as time evolves, with the potential of the future continually becoming the certainty of the past; spacetime itself evolves, as do the entities within it. However this time evolution is not related to any preferred surfaces in spacetime; rather it is associated with the evolution of proper time along families of world lines. The default state of fundamental physics should not be taken to be a time irreversible evolution of physical states: it is an ongoing irreversible development of time itself.

  16. TITLE AUTHORS SUBJECT SUBJECT RELATED DESCRIPTION PUBLISHER AVAILABILI...

    Office of Scientific and Technical Information (OSTI)

    Real time sub math display inline mi mi math ngstrom imaging of reversible and irreversible conformations in rhodium catalysts and graphene Kisielowski Christian Wang Lin Wang...

  17. "Title","Creator/Author","Publication Date","OSTI Identifier...

    Office of Scientific and Technical Information (OSTI)

    Real-time sub-<mi>>ngstrom imaging of reversible and irreversible conformations in rhodium catalysts and graphene","Kisielowski, Christian;...

  18. Time is not the problem

    E-Print Network [OSTI]

    Olaf Dreyer

    2009-04-22

    Attempts to quantize general relativity encounter an odd problem. The Hamiltonian that normally generates time evolution vanishes in the case of general relativity as a result of diffeomorphism invariance. The theory seems to be saying that time does not exist. The most obvious feature of our world, namely that time seems to progress and that the world changes accordingly becomes a problem in this presumably fundamental theory. This is called the problem of time. In this essay we argue that this problem is the result of an unphysical idealization. We are caught in this "problem of time" trap because we took a wrong turn in the early days of relativity by permanently including a split of geometry and matter into our physical theories. We show that another possibility exists that circumvents the problem of time and also sheds new light on other problems like the cosmological constant problem and the horizon problem in early universe cosmology.

  19. Three-body dwell time

    SciTech Connect (OSTI)

    Kelkar, N. G.

    2010-06-15

    The lifetime of an unstable state or resonance formed as an intermediate state in two-body scattering is known to be related to the dwell time or the time spent within a given region of space by the two interacting particles. This concept is extended to the case of three-body systems and a relation connecting the three-body dwell time with the two-body dwell times of the substructures of the three-body system is derived for the case of separable wave functions. The Kapur-Peierls formalism is revisited to discover one of the first definitions of dwell time in the literature. An extension of the Kapur-Peierls formalism to the three-body case shows that the lifetime of a three-body resonance can indeed be given by the three-body dwell time.

  20. Reactor control rod timing system

    DOE Patents [OSTI]

    Wu, Peter T. K. (Clifton Park, NY)

    1982-01-01

    A fluid driven jet-edge whistle timing system for control rods of a nuclear reactor for producing real-time detection of the timing of each control rod in its scram operation. An important parameter in reactor safety, particularly for liquid metal fast breeder reactors (LMFBR), is the time deviation between the time the control rod is released and the time the rod actually reaches the down position. The whistle has a nearly pure tone signal with center frequency (above 100 kHz) far above the frequency band in which the energy of the background noise is concentrated. Each control rod can be fitted with a whistle with a different frequency so that there is no ambiguity in differentiating the signal from each control rod.

  1. Reactor control rod timing system

    SciTech Connect (OSTI)

    Wu, P.T.

    1982-02-09

    A fluid driven jet-edge whistle timing system for control rods of a nuclear reactor for producing real-time detection of the timing of each control rod in its scram operation. An important parameter in reactor safety, particularly for liquid metal fast breeder reactors (LMFBR), is the time deviation between the time the control rod is released and the time the rod actually reaches the down position. The whistle has a nearly pure tone signal with center frequency (Above 100 kHz) far above the frequency band in which the energy of the background noise is concentrated. Each control rod can be fitted with a whistle with a different frequency so that there is no ambiguity in differentiating the signal from each control rod.

  2. Commencement Ceremony Department Time Location Department and Major Time Location

    E-Print Network [OSTI]

    Kaji, Hajime

    Engineering 15:30 Bldg. 63 Classroom 01 (2nd Fl.) Industrial and Management Systems Engineering 15:30 Bldg. 63 and Management 15:30 Bldg. 63 Classroom 01 (2nd Fl.) Department Time Location Department and Major Time Location:30 Bldg. 57 202 Modern Mechanical Engineering 10:30 Bldg. 57 202 Industrial and Management Systems

  3. 49 Stress-timed vs. Syllable-timed Languages

    E-Print Network [OSTI]

    Mehler, Jacques

    49 Stress-timed vs. Syllable- timed Languages Marina Nespor Mohinish Shukla Jacques Mehler 1; Prince 1983; Nespor & Vogel 1989; chapter 43: representations of word stress), the element that "establishes order" in the flow of speech is stress: universally, stressed and unstressed positions alternate

  4. Time Structure of Muonic Showers

    E-Print Network [OSTI]

    L. Cazon; R. A. Vazquez; A. A. Watson; E. Zas

    2003-11-10

    An analytical description of the time structure of the pulses induced by muons in air showers at ground level is deduced assuming the production distance distribution for the muons can be obtained elsewhere. The results of this description are compared against those obtained from simulated showers using AIRES. Major contributions to muon time delays are identified and a relation between the time structure and the depth distribution is unveiled.

  5. Seismic velocity estimation from time migration

    E-Print Network [OSTI]

    Cameron, Maria Kourkina

    2007-01-01

    v List of Tables Comparison of time migration and depthof seismic imaging: time migration and depth migration. TimeComparison of time migration and depth migration Adequate

  6. Time and maps Menno-Jan Kraak

    E-Print Network [OSTI]

    Time and maps Menno-Jan Kraak Time and maps ! · Why interested in time? · What is time and · How is time perceived? · How is time represented? Why interested in time? GIScience perspective) - analysis of changes over time - analysis of patterns of change over time ! · Development of methods

  7. Quantum gravity, the origin of time and time's arrow

    SciTech Connect (OSTI)

    Moffat, J.W. (Univ. of Toronto, Ontario (Canada))

    1993-03-01

    The local Lorentz and diffeomorphism symmetries of Einstein's gravitational theory are spontaneously broken by a Higgs mechanism by invoking a phase transition in the early universe, at a critical temperature [Tc] below which the symmetry is restored. The spontaneous breakdown of the vacuum state generates an external time, and the wave function of the universe satisfies a time-dependent Schroedinger equation, which reduces to the Wheeler-deWitt equation in the classical regime for T<[Tc], allowing a semiclassical WKB approximation to the wave function. The conservation of energy is spontaneously violated for T>[Tc], and matter is created fractions of seconds after the big bang, generating the matter in the Universe. The time direction of the vacuum expectation value of the scalar Higgs field generates a time asymmetry, which defines the cosmological arrow of time and the direction of increasing entropy as the Lorentz symmetry is restored at low temperatures. 52 refs.

  8. Assessing Energy Impact of Plug-In Hybrid Electric Vehicles: Significance of Daily Distance Variation over Time and Among Drivers

    SciTech Connect (OSTI)

    Lin, Zhenhong [ORNL; Greene, David L [ORNL

    2012-01-01

    Accurate assessment of the impact of plug-in hybrid electric vehicles (PHEVs) on petroleum and electricity consumption is a necessary step toward effective policies. Variations in daily vehicle miles traveled (VMT) over time and among drivers affect PHEV energy impact, but the significance is not well understood. This paper uses a graphical illustration, a mathematical derivation, and an empirical study to examine the cause and significance of such an effect. The first two methods reveal that ignoring daily variation in VMT always causes underestimation of petroleum consumption and overestimation of electricity consumption by PHEVs; both biases increase as the assumed PHEV charge-depleting (CD) range moves closer to the average daily VMT. The empirical analysis based on national travel survey data shows that the assumption of uniform daily VMT over time and among drivers causes nearly 68% underestimation of expected petroleum use and nearly 48% overestimation of expected electricity use by PHEVs with a 40-mi CD range (PHEV40s). Also for PHEV40s, consideration of daily variation in VMT over time but not among drivers similar to the way the utility factor curve is derived in SAE Standard SAE J2841 causes underestimation of expected petroleum use by more than 24% and overestimation of expected electricity use by about 17%. Underestimation of petroleum use and overestimation of electricity use increase with larger-battery PHEVs.

  9. thesis abstract: Orang-utan genes in space and time: the impact of evolutionary processes of diversification on Bornean orang-utans

    E-Print Network [OSTI]

    Arora, Natasha

    2012-01-01

    expansion  of  orang? utans  throughout  Borneo,  current  populations  show high genetic differentiation, both at the mi? tochondrial and at the nuclear 

  10. Time Dependence of ACIS Contamination

    E-Print Network [OSTI]

    Grant, Catherine E.

    Time Dependence of ACIS Contamination Chandra Calibration Workshop 27 October 2003 Catherine Grant Source · Measuring the decay · Monitoring contamination with the ECS · Models of ECS time dependence · Monitoring contamination with the LETG · Agreement between models #12;ACIS External Calibration Source

  11. STARBASE: MANAGING CONTENTION AND TIMING

    E-Print Network [OSTI]

    Son, Sang H.

    systems (RT­DBMS) has primarily based on simulation. This chapter discusses how current real­time technology has been applied to architect an actual RT­DBMS on a real­time microkernel operating system. A real RT­DBMS must confront many practical issues which simulations typically ignore: race conditions

  12. The Time of Our Lives

    E-Print Network [OSTI]

    Mellor, David Hugh

    2001-01-01

    The article shows how McTaggart’s distinction between A- and B-series ways of locating events in time prompted and enabled the twentieth century’s most important advances in the philosophy of time. It argues that, even if the B-series represents...

  13. The Parkes Pulsar Timing Array

    E-Print Network [OSTI]

    R N Manchester

    2006-04-13

    Given sufficient sensitivity, pulsar timing observations can make a direct detection of gravitational waves passing over the Earth. Pulsar timing is most sensitive to gravitational waves with frequencies in the nanoHertz region, with the most likely astronomical sources being binary super-massive black holes in galaxy cores. The Parkes Pulsar Timing Array project uses the Parkes 64-m radio telescope to make precision timing observations of a sample of about 20 millisecond pulsars with a principal goal of making a direct detection of gravitational waves. Observations commenced about one year ago and so far sub-microsecond timing residuals have been achieved for more than half of these pulsars. New receiver and software systems are being developed with the aim of reducing these residuals to the level believed necessary for a positive detection of gravitational waves.

  14. Time-Dependent Lagrangian Biomechanics

    E-Print Network [OSTI]

    Ivancevic, Tijana T

    2009-01-01

    In this paper we present the time-dependent generalization of an 'ordinary' autonomous human musculo-skeletal biomechanics. We start with the configuration manifold of human body, given as a set of its all active degrees of freedom (DOF). This is a Riemannian manifold with a material metric tensor given by the total mass-inertia matrix of the human body segments. This is the base manifold for standard autonomous biomechanics. To make its time-dependent generalization, we need to extend it with a real time axis. On this extended configuration space we develop time-dependent biomechanical Lagrangian dynamics, using derived jet spaces of velocities and accelerations, as well as the underlying geometric evolution of the mass-inertia matrix. Keywords: Human time-dependent biomechanics, configuration manifold, jet spaces, geometric evolution

  15. An integrated time-of-flight versus residual energy subsystem for a compact dual ion composition experiment for space plasmas

    SciTech Connect (OSTI)

    Desai, M. I.; McComas, D. J.; Allegrini, F.; Livi, S. A.; Ogasawara, K.; Ebert, R. W.; Weidner, S. E.; Alexander, N.

    2015-05-15

    We have developed a novel concept for a Compact Dual Ion Composition Experiment (CoDICE) that simultaneously provides high quality plasma and energetic ion composition measurements over 6 decades in ion energy in a wide variety of space plasma environments. CoDICE measures the two critical ion populations in space plasmas: (1) mass and ionic charge state composition and 3D velocity and angular distributions of ?10 eV/q–40 keV/q plasma ions—CoDICE-Lo and (2) mass composition, energy spectra, and angular distributions of ?30 keV–10 MeV energetic ions—CoDICE-Hi. CoDICE uses a common, integrated Time-of-Flight (TOF) versus residual energy (E) subsystem for measuring the two distinct ion populations. This paper describes the CoDICE design concept, and presents results of the laboratory tests of the TOF portion of the TOF vs. E subsystem, focusing specifically on (1) investigation of spill-over and contamination rates on the start and stop microchannel plate (MCP) anodes vs. secondary electron steering and focusing voltages, scanned around their corresponding model-optimized values, (2) TOF measurements and resolution and angular resolution, and (3) cross-contamination of the start and stop MCPs’ singles rates from CoDICE-Lo and -Hi, and (4) energy resolution of avalanche photodiodes near the lower end of the CoDICE-Lo energy range. We also discuss physical effects that could impact the performance of the TOF vs. E subsystem in a flight instrument. Finally, we discuss advantages of the CoDICE design concept by comparing with capabilities and resources of existing flight instruments.

  16. Time parallel gravitational collapse simulation

    E-Print Network [OSTI]

    Kreienbuehl, Andreas; Ruprecht, Daniel; Krause, Rolf

    2015-01-01

    This article demonstrates the applicability of the parallel-in-time method Parareal to the numerical solution of the Einstein gravity equations for the spherical collapse of a massless scalar field. To account for the shrinking of the spatial domain in time, a tailored load balancing scheme is proposed and compared to load balancing based on number of time steps alone. The performance of Parareal is studied for both the sub-critical and black hole case; our experiments show that Parareal generates substantial speedup and, in the super-critical regime, can also reproduce the black hole mass scaling law.

  17. Uncertainty and the timing of an urban congestion relief investment. The no-land case

    E-Print Network [OSTI]

    Saphores, JDM; Boarnet, M G

    2006-01-01

    investment lag; real options. JEL codes: D61, D81, R42. I.stopping problem using real options (see Dixit and Pindyck [make a binding decision. The real options approach has been

  18. Uncertainty and the timing of an urban congestion relief investment - The no-land case

    E-Print Network [OSTI]

    Saphores, Jean-Daniel M; Boarnet, Marlon G.

    2006-01-01

    investment lag; real options. JEL codes: D61, D81, R42. I.stopping problem using real options (see Dixit and Pindyck [make a binding decision. The real options approach has been

  19. User Experiment Time-Line

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    User Experiment Time-Line Event Target Call for proposal 2 months before proposals are due PAC Proposals Due 7 weeks before PAC meeting TAC Report for PAC Proposals (includes...

  20. Time Machine at the LHC

    E-Print Network [OSTI]

    I. Ya. Aref'eva; I. V. Volovich

    2007-10-25

    Recently, black hole and brane production at CERN's Large Hadron Collider (LHC) has been widely discussed. We suggest that there is a possibility to test causality at the LHC. We argue that if the scale of quantum gravity is of the order of few TeVs, proton-proton collisions at the LHC could lead to the formation of time machines (spacetime regions with closed timelike curves) which violate causality. One model for the time machine is a traversable wormhole. We argue that the traversable wormhole production cross section at the LHC is of the same order as the cross section for the black hole production. Traversable wormholes assume violation of the null energy condition (NEC) and an exotic matter similar to the dark energy is required. Decay of the wormholes/time machines and signatures of time machine events at the LHC are discussed.

  1. Vocal Timing in the Bat 

    E-Print Network [OSTI]

    Jarvis, Jenna N

    2013-05-01

    respond to continuous noise by increasing their call rate, and that the switch between the responses to intermittent noise and continuous noise occurs at a duty cycle of 50% or higher. Overall, this dissertation establishes that bats alter the timing...

  2. TIME SCHEDULE WINTER QUARTER 1970

    E-Print Network [OSTI]

    Kaminsky, Werner

    MASTER CON TIME SCHEDULE WINTER QUARTER 1970 ADVANCE REGISTRATION NOVEMBER 3-21 IN, please leave it or pass it along so that other students may use it. #12;Winter Quarter 1970. Examination

  3. Modeling of Time with Metamaterials

    E-Print Network [OSTI]

    Igor I. Smolyaninov; Yu-Ju Hung

    2011-05-12

    Metamaterials have been already used to model various exotic "optical spaces". Here we demonstrate that mapping of monochromatic extraordinary light distribution in a hyperbolic metamaterial along some spatial direction may model the "flow of time". This idea is illustrated in experiments performed with plasmonic hyperbolic metamaterials. Appearance of the "statistical arrow of time" is examined in an experimental scenario which emulates a Big Bang-like event.

  4. Voice-Onset-Time in the Perception of Foreign Accent by Native Listeners of Spanish

    E-Print Network [OSTI]

    Gonzalez-Bueno, Manuela

    1997-01-01

    of phonetic parameters measured in the speech of second language learners are often intermediate to those typical of monolingual speakers of the native and target language" (Pinkerton 1972, Suomi 1976, Flege 1980). An acceptable pronunciation of Spanish... and Fred D. Brandt 1987. Burst and Transition Cues to Voicing Perception for Spoken Initial Stops by Impaired and Normal- Hearing Listeners. Journal of Speech and Hearing Research, 30, 3: 311. Suomi, K. 1976. English Voiceless and Voiced Stops...

  5. Geothermal Exploration Cost and Time

    SciTech Connect (OSTI)

    Jenne, Scott

    2013-02-13

    The Department of Energy’s Geothermal Technology Office (GTO) provides RD&D funding for geothermal exploration technologies with the goal of lowering the risks and costs of geothermal development and exploration. The National Renewable Energy Laboratory (NREL) was tasked with developing a metric in 2012 to measure the impacts of this RD&D funding on the cost and time required for exploration activities. The development of this cost and time metric included collecting cost and time data for exploration techniques, creating a baseline suite of exploration techniques to which future exploration cost and time improvements can be compared, and developing an online tool for graphically showing potential project impacts (all available at http://en.openei.org/wiki/Gateway: Geothermal). This paper describes the methodology used to define the baseline exploration suite of techniques (baseline), as well as the approach that was used to create the cost and time data set that populates the baseline. The resulting product, an online tool for measuring impact, and the aggregated cost and time data are available on the Open Energy Information website (OpenEI, http://en.openei.org) for public access. - Published 01/01/2013 by US National Renewable Energy Laboratory NREL.

  6. On the Nature of Time

    E-Print Network [OSTI]

    Radovan, Mario

    2015-01-01

    The paper puts forward a conceptual framework in which the phenomenon of time can be presented and discussed in a proper way. We argue that change is ontologically and epistemologically a more basic phenomenon than time. Time is an abstract entity created by the human mind on the basis of the experience of change. Physical reality is a process of ceaseless becoming and vanishing; time is not a part of that process. Time is the abstract bank in relation to which we measure the intensity and amount of the flow (change) of physical reality. We must differentiate physical reality from abstract entities (language) by means of which we speak about this reality. It is necessary to differentiate a formal description (formulas) from its interpretation: a correct formal description can be interpreted in a logically inconsistent and factually wrong way. We argue that the discourse about the relativity of time joins (mixes) physical reality and language, and gives an inconsistent interpretation of correct formulas. Regar...

  7. Search for proton decay via <mi>p>?<mi>?K>+ using 260 <mi>kiloton·year> data of Super-Kamiokande

    SciTech Connect (OSTI)

    Abe, K.; Hayato, Y.; Iyogi, K.; Kameda, J.; Miura, M.; Moriyama, S.; Nakahata, M.; Nakayama, S.; Wendell, R.?A.; Sekiya, H.; Shiozawa, M.; Suzuki, Y.; Takeda, A.; Takenaga, Y.; Ueno, K.; Yokozawa, T.; Kaji, H.; Kajita, T.; Kaneyuki, K.; Lee, K.?P.; Okumura, K.; McLachlan, T.; Labarga, L.; Kearns, E.; Raaf, J.?L.; Stone, J.?L.; Sulak, L.?R.; Goldhaber, M.; Bays, K.; Carminati, G.; Kropp, W.?R.; Mine, S.; Renshaw, A.; Smy, M.?B.; Sobel, H.?W.; Ganezer, K.?S.; Hill, J.; Keig, W.?E.; Jang, J.?S.; Kim, J.?Y.; Lim, I.?T.; Albert, J.?B.; Scholberg, K.; Walter, C.?W.; Wongjirad, T.; Ishizuka, T.; Tasaka, S.; Learned, J.?G.; Matsuno, S.; Smith, S.?N.; Hasegawa, T.; Ishida, T.; Ishii, T.; Kobayashi, T.; Nakadaira, T.; Nakamura, K.; Nishikawa, K.; Oyama, Y.; Sakashita, K.; Sekiguchi, T.; Tsukamoto, T.; Suzuki, A.?T.; Takeuchi, Y.; Ieki, K.; Ikeda, M.; Kubo, H.; Minamino, A.; Murakami, A.; Nakaya, T.; Fukuda, Y.; Choi, K.; Itow, Y.; Mitsuka, G.; Miyake, M.; Mijakowski, P.; Hignight, J.; Imber, J.; Jung, C.?K.; Taylor, I.; Yanagisawa, C.; Ishino, H.; Kibayashi, A.; Koshio, Y.; Mori, T.; Sakuda, M.; Takeuchi, J.; Kuno, Y.; Kim, S.?B.; Okazawa, H.; Choi, Y.; Nishijima, K.; Koshiba, M.; Totsuka, Y.; Yokoyama, M.; Martens, K.; Marti, Ll.; Obayashi, Y.; Vagins, M.?R.; Chen, S.; Sui, H.; Yang, Z.; Zhang, H.; Connolly, K.; Dziomba, M.; Wilkes, R.?J.

    2014-10-14

    We have searched for proton decay via p??K+ using Super-Kamiokande data from April 1996 to February 2013, 260 kiloton•year exposure in total. No evidence for this proton decay mode is found. A lower limit of the proton lifetime is set to ?/B(p??K+)>5.9×1033 years at 90% confidence level.

  8. Reduction in maximum time uncertainty of paired time signals

    DOE Patents [OSTI]

    Theodosiou, G.E.; Dawson, J.W.

    1981-02-11

    Reduction in the maximum time uncertainty (t/sub max/ - t/sub min/) of a series of paired time signals t/sub 1/ and t/sub 2/ varying between two input terminals and representative of a series of single events where t/sub 1/ less than or equal to t/sub 2/ and t/sub 1/ + t/sub 2/ equals a constant, is carried out with a circuit utilizing a combination of OR and AND gates as signal selecting means and one or more time delays to increase the minimum value (t/sub min/) of the first signal t/sub 1/ closer to t/sub max/ and thereby reduce the difference. The circuit may utilize a plurality of stages to reduce the uncertainty by factors of 20 to 800.

  9. Early Time Dynamics in Heavy Ion Collisions from CGC and from AdS/CFT

    E-Print Network [OSTI]

    Yuri V. Kovchegov

    2009-09-11

    We review two different theoretical approaches to the strong interaction dynamics at the early times immediately following heavy ion collisions. One approach is based on small-coupling physics of the Color Glass Condensate (CGC). The other approach is based on Anti-de Sitter space/Conformal Field Theory (AdS/CFT) correspondence and may be applicable to describing large-coupling QCD interactions. We point out that in terms of theoretical tools the two approaches are somewhat similar: in CGC one deals with classical gluon fields produced in a nuclear shock wave collision, while in AdS/CFT one studies classical gravity in a gravitational shock wave collision. We stress, however, that the resulting physics is different: the classical gluon fields in CGC lead to a free-streaming medium produced in heavy ion collisions, while the classical gravity in the 5-dimensional AdS bulk is likely to lead to ideal hydrodynamics description of the produced medium. Also, the valence quarks in colliding nuclei in CGC continue along their light cone trajectories after the collision with very little recoil, while we show that in AdS the colliding nuclei are likely to lose most of their energy in the collision and stop.

  10. Measuring time with physical clocks

    E-Print Network [OSTI]

    Esteban Castro-Ruiz; Flaminia Giacomini; ?aslav Brukner

    2015-07-07

    In general relativity, the picture of spacetime assigns an ideal clock to each spacetime point. Being ideal, gravitational effects due to these clocks are ignored and the flow of time according to one clock is not affected by the presence of surrounding clocks. However, if time is defined operationally, as a pointer position of a physical clock that obeys the laws of quantum mechanics and general relativity, such a picture is at most a convenient fiction. We show that the mass-energy equivalence implies gravitational interaction between the clocks, while the superposition of energy eigenstates leads to a non-fixed metric background. Based only on the assumption that both quantum mechanics and general relativity are valid in this situation, we show that the clocks necessarily get entangled through time dilation effect, which eventually leads to a loss of coherence of a single clock. Hence, the time as measured by a single clock is not well-defined. However, the general relativistic notion of time is recovered in the classical limit of clocks.

  11. Static timing analysis in VLSI design

    E-Print Network [OSTI]

    Zhou, Shuo

    2006-01-01

    II.B Static Timing AnalysisStatic Timing Analysis in the Design Flow FalseChip Analysis . . . . . . . . . . . . . . I.C Static Timing

  12. Time Series Analysis 1 Time series in astronomy

    E-Print Network [OSTI]

    Babu, G. Jogesh

    (supernovae, gamma-ray bursts) Difficulties in astronomical time series Gapped data streams: Diurnal & monthly phenomena: thermonuclear (novae, X-ray bursts), magnetic reconnection (solar/stellar flares), star death); pulsation (helioseismology, Cepheids) Stochastic phenomena: accretion (CVs, X-ray binaries, Seyfert gals

  13. Lu.sub.1-xI.sub.3:Ce.sub.x--a scintillator for gamma ray spectroscopy and time-of-flight PET

    DOE Patents [OSTI]

    Shah, Kanai S.

    2007-02-06

    The present invention concerns very fast scintillator materials comprising lutetium iodide doped with Cerium (Lu.sub.1-xI.sub.3:Ce.sub.x; LuI.sub.3:Ce). The LuI.sub.3 scintillator material has surprisingly good characteristics including high light output, high gamma ray stopping efficiency, fast response, low cost, good proportionality, and minimal afterglow that the material is useful for gamma ray spectroscopy, medical imaging, nuclear and high energy physics research, diffraction, non-destructive testing, nuclear treaty verification and safeguards, and geological exploration. The timing resolution of the scintillators of the present invention provide compositions capable of resolving the position of an annihilation event within a portion of a human body cross-section.

  14. Time of flight mass spectrometer

    DOE Patents [OSTI]

    Ulbricht, Jr., William H. (Arvada, CO)

    1984-01-01

    A time-of-flight mass spectrometer is described in which ions are desorbed from a sample by nuclear fission fragments, such that desorption occurs at the surface of the sample impinged upon by the fission fragments. This configuration allows for the sample to be of any thickness, and eliminates the need for complicated sample preparation.

  15. TIME-RESOLVED VIBRATIONAL SPECTROSCOPY

    SciTech Connect (OSTI)

    Andrei Tokmakoff, MIT; Paul Champion, Northeastern University; Edwin J. Heilweil, NIST; Keith A. Nelson, MIT; Larry Ziegler, Boston University

    2009-05-14

    This document contains the Proceedings from the 14th International Conference on Time-Resolved Vibrational Spectroscopy, which was held in Meredith, NH from May 9-14, 2009. The study of molecular dynamics in chemical reaction and biological processes using time-resolved spectroscopy plays an important role in our understanding of energy conversion, storage, and utilization problems. Fundamental studies of chemical reactivity, molecular rearrangements, and charge transport are broadly supported by the DOE�s Office of Science because of their role in the development of alternative energy sources, the understanding of biological energy conversion processes, the efficient utilization of existing energy resources, and the mitigation of reactive intermediates in radiation chemistry. In addition, time-resolved spectroscopy is central to all five of DOE�s grand challenges for fundamental energy science. The Time-Resolved Vibrational Spectroscopy conference is organized biennially to bring the leaders in this field from around the globe together with young scientists to discuss the most recent scientific and technological advances. The latest technology in ultrafast infrared, Raman, and terahertz spectroscopy and the scientific advances that these methods enable were covered. Particular emphasis was placed on new experimental methods used to probe molecular dynamics in liquids, solids, interfaces, nanostructured materials, and biomolecules.

  16. ANDERSON LOCALIZATION FOR TIME PERIODIC

    E-Print Network [OSTI]

    disorder, Anderson localization in Z d is stable un- der localized time-periodic perturbations by proving random Schrodinger operators at large disorder has been well known since the seminal work of Fr is approximated by the potential V . The equation governing the system is (1.5) i @ @t = (#1; + V ) on Z d #2

  17. The TESLA Time Projection Chamber

    E-Print Network [OSTI]

    Nabil Ghodbane

    2002-12-12

    A large Time Projection Chamber is proposed as part of the tracking system for a detector at the TESLA electron positron linear collider. Different ongoing R&D studies are reviewed, stressing progress made on a new type readout technique based on Micro-Pattern Gas Detectors.

  18. Percutaneous Radiofrequency Ablation of Painful Spinal Tumors Adjacent to the Spinal Cord with Real-Time Monitoring of Spinal Canal Temperature: A Prospective Study

    SciTech Connect (OSTI)

    Nakatsuka, Atsuhiro, E-mail: nakatuka@clin.medic.mie-u.ac.jp; Yamakado, Koichiro; Takaki, Haruyuki; Uraki, Junji; Makita, Masashi; Oshima, Fumiyoshi; Takeda, Kan [Mie University School of Medicine, Department of Radiology (Japan)

    2009-01-15

    PurposeTo prospectively evaluate the feasibility, safety, and clinical utility of bone radiofrequency (RF) ablation with real-time monitoring of the spinal canal temperature for the treatment of spinal tumors adjacent to the spinal cord.Materials and MethodsOur Institutional Review Board approved this study. Patients gave informed consent. The inclusion criteria were (a) a painful spinal metastasis and (b) a distance of 1 cm or less between the metastasis and the spinal cord. The thermocouple was placed in the spinal canal under CT fluoroscopic guidance. When the spinal canal temperature reached 45{sup o}C, RF application was immediately stopped. RF ablation was considered technically successful when the procedure was performed without major complications. Clinical success was defined as a fall in the visual analogue scale score of at least 2 points.ResultsTen patients with spinal tumors measuring 3-8 cm (mean, 4.9 {+-} 1.5 cm) were enrolled. The distance between the tumor and the spinal cord was 1-6 mm (mean, 2.4 {+-} 1.6 mm). All procedures were judged technically successful (100%). The spinal canal temperature did not exceed 45{sup o}C in 9 of the 10 patients (90%). In the remaining patient, the temperature rose to 48{sup o}C, resulting in transient neural damage, although RF application was immediately stopped when the temperature reached 45{sup o}C. Clinical success was achieved within 1 week in all patients (100%).ConclusionBone RF ablation with real-time monitoring of the spinal canal temperature is feasible, safe, and clinically useful for the treatment of painful spinal metastases adjacent to the spinal cord.

  19. Theory of Earthquake Recurrence Times

    E-Print Network [OSTI]

    A. Saichev; D. Sornette

    2006-05-31

    The statistics of recurrence times in broad areas have been reported to obey universal scaling laws, both for single homogeneous regions (Corral, 2003) and when averaged over multiple regions (Bak et al.,2002). These unified scaling laws are characterized by intermediate power law asymptotics. On the other hand, Molchan (2005) has presented a mathematical proof that, if such a universal law exists, it is necessarily an exponential, in obvious contradiction with the data. First, we generalize Molchan's argument to show that an approximate unified law can be found which is compatible with the empirical observations when incorporating the impact of the Omori law of earthquake triggering. We then develop the full theory of the statistics of inter-event times in the framework of the ETAS model of triggered seismicity and show that the empirical observations can be fully explained. Our theoretical expression fits well the empirical statistics over the whole range of recurrence times, accounting for different regimes by using only the physics of triggering quantified by Omori's law. The description of the statistics of recurrence times over multiple regions requires an additional subtle statistical derivation that maps the fractal geometry of earthquake epicenters onto the distribution of the average seismic rates in multiple regions. This yields a prediction in excellent agreement with the empirical data for reasonable values of the fractal dimension $d \\approx 1.8$, the average clustering ratio $n \\approx 0.9$, and the productivity exponent $\\alpha \\approx 0.9$ times the $b$-value of the Gutenberg-Richter law.

  20. Treating Time Travel Quantum Mechanically

    E-Print Network [OSTI]

    John-Mark A. Allen

    2014-10-10

    The fact that closed timelike curves (CTCs) are permitted by general relativity raises the question as to how quantum systems behave when time travel to the past occurs. Research into answering this question by utilising the quantum circuit formalism has given rise to two theories: Deutschian-CTCs (D-CTCs) and "postselected" CTCs (P-CTCs). In this paper the quantum circuit approach is thoroughly reviewed, and the strengths and shortcomings of D-CTCs and P-CTCs are presented in view of their non-linearity and time travel paradoxes. In particular, the "equivalent circuit model"---which aims to make equivalent predictions to D-CTCs, while avoiding some of the difficulties of the original theory---is shown to contain errors. The discussion of D-CTCs and P-CTCs is used to motivate an analysis of the features one might require of a theory of quantum time travel, following which two overlapping classes of new theories are identified. One such theory, the theory of "transition probability" CTCs (T-CTCs), is fully developed. The theory of T-CTCs is shown not to have certain undesirable features---such as time travel paradoxes, the ability to distinguish non-orthogonal states with certainty, and the ability to clone or delete arbitrary pure states---that are present with D-CTCs and P-CTCs. The problems with non-linear extensions to quantum mechanics are discussed in relation to the interpretation of these theories, and the physical motivations of all three theories are discussed and compared.

  1. The Parkes Pulsar Timing Array

    E-Print Network [OSTI]

    R. N. Manchester

    2007-11-12

    Detection and study of gravitational waves from astrophysical sources is a major goal of current astrophysics. Ground-based laser-interferometer systems such as LIGO and VIRGO are sensitive to gravitational waves with frequencies of order 100 Hz, whereas space-based systems such as LISA are sensitive in the millihertz regime. Precise timing observations of a sample of millisecond pulsars widely distributed on the sky have the potential to detect gravitational waves at nanohertz frequencies. Potential sources of such waves include binary super-massive black holes in the cores of galaxies, relic radiation from the inflationary era and oscillations of cosmic strings. The Parkes Pulsar Timing Array (PPTA) is an implementation of such a system in which 20 millisecond pulsars have been observed using the Parkes radio telescope at three frequencies at intervals of two -- three weeks for more than two years. Analysis of these data has been used to limit the gravitational wave background in our Galaxy and to constrain some models for its generation. The data have also been used to investigate fluctuations in the interstellar and Solar-wind electron density and have the potential to investigate the stability of terrestrial time standards and the accuracy of solar-system ephemerides.

  2. Smolt Condition and Timing of Arrival at Lower Granite Reservoir, 1984 Annual Report.

    SciTech Connect (OSTI)

    Scully, Richard J.; Buettner, Edwin W.

    1986-02-01

    Hatcheries released 9.3 million chinook salmon and 6.3 million steelhead smolts and presmolts upriver from Lower Granite Reservoir for migration in spring, 1984. Peak passage of yearling chinook salmon occurred the third week in April at both Whitebird and Snake River traps. Passage of steelhead was still increasing when high water stopped trapping in mid-May. Average migration rate between release sites and Snake River (the head of Lower Granite Reservoir) was 13.2 miles/day and from that point on through the reservoir to the dam, 1.9 miles/day. Salmon River discharge, when considered along with other environmental factors, had the greatest effect on migration rate of smolts branded both at hatcheries and at the Whitebird trap and migrating to the head of Lower Granite Reservoir. Migration rate for steelhead released from Dworshak Hatchery and recaptured at the Clearwater trap was 34 miles/day. Survival rates to the Snake River trap of branded chinook salmon smolts released at Hells Canyon Dam, Rapid River, South Fork Salmon and Decker Flat were 52%, 65%, 68% and 35%, respectively. Classical descaling, where at least 40% of the scales are missing from at least two of five areas on the side of a smolt, ranged from 0 to 5.3% at hatcheries for chinook salmon and was less than 1% for steelhead. Scattered descaling, where at least 10% of scales are missing from at least one side of a fish, was always more extensive than was classical descaling, ranging from 2.5 times greater for Clearwater hatchery steelhead to 6.8 times greater for Clearwater wild steelhead. Mean total length of chinook salmon yearlings was the same at all the traps, i.e., 128 mm (117 mm fork length) +- 1 mm.

  3. Timing the Parkes Multibeam Pulsars

    E-Print Network [OSTI]

    R. N. Manchester; A. G. Lyne; F. Camilo; V. M. Kaspi; I. H. Stairs; F. Crawford; D. J. Morris; J. F. Bell; N. D'Amico

    1999-11-17

    Measurement of accurate positions, pulse periods and period derivatives is an essential follow-up to any pulsar survey. The procedures being used to obtain timing parameters for the pulsars discovered in the Parkes multibeam pulsar survey are described. Completed solutions have been obtained so far for about 80 pulsars. They show that the survey is preferentially finding pulsars with higher than average surface dipole magnetic fields. Eight pulsars have been shown to be members of binary systems and some of the more interesting results relating to these are presented.

  4. Regression quantiles for time series

    E-Print Network [OSTI]

    Cai, Zongwu

    2002-02-01

    ~see, e+g+, Ibragimov and Linnik, 1971, p+ 316!+ Namely, partition REGRESSION QUANTILES FOR TIME SERIES 187 $1, + + + , n% into 2qn 1 1 subsets with large block of size r 5 rn and small block of size s 5 sn+ Set q 5 qn 5 ? n rn 1 sn? , (A.7) where {x...! are the standard Lindeberg–Feller conditions for asymptotic normality of Qn,1 for the independent setup+ Let us first establish ~A+8!+ To this effect, we define the large-block size rn by rn 5 {~nhn!102} and the small-block size sn 5 {~nhn!1020log n}+ Then, as n r...

  5. Real time infrared aerosol analyzer

    DOE Patents [OSTI]

    Johnson, Stanley A. (Countryside, IL); Reedy, Gerald T. (Bourbonnais, IL); Kumar, Romesh (Naperville, IL)

    1990-01-01

    Apparatus for analyzing aerosols in essentially real time includes a virtual impactor which separates coarse particles from fine and ultrafine particles in an aerosol sample. The coarse and ultrafine particles are captured in PTFE filters, and the fine particles impact onto an internal light reflection element. The composition and quantity of the particles on the PTFE filter and on the internal reflection element are measured by alternately passing infrared light through the filter and the internal light reflection element, and analyzing the light through infrared spectrophotometry to identify the particles in the sample.

  6. Time Scales in Spectator Fragmentation

    E-Print Network [OSTI]

    C. Schwarz; for the ALADIN collaboration

    2000-09-07

    Proton-proton correlations and correlations of p-alpha, d-alpha, and t-alpha from spectator decays following Au + Au collisions at 1000 AMeV have been measured with an highly efficient detector hodoscope. The constructed correlation functions indicate a moderate expansion and low breakup densities similar to assumptions made in statistical multifragmentation models. In agreement with a volume breakup rather short time scales were deduced employing directional cuts in proton-proton correlations. PACS numbers: 25.70.Pq, 21.65.+f, 25.70.Mn

  7. Time-Bounded Verification Joel Ouaknine1

    E-Print Network [OSTI]

    Worrell, James

    Time-Bounded Verification Jo¨el Ouaknine1 , Alexander Rabinovich2 , and James Worrell1 1 Oxford prob- lems for timed automata over time intervals of fixed, bounded length. One of our main results is that time-bounded language inclusion for timed automata is 2EXPSPACE-complete. We also investigate the satis

  8. Measurement of the structure function of the nearly free neutron using spectator tagging in inelastic <mi mathvariant='normal'>Hmi>2 ( <mi>e>, <mi>emi>'<mi>ps> ) <mi>X> scattering with CLAS

    SciTech Connect (OSTI)

    Tkachenko, S.; Baillie, N.; Kuhn, S. E.; Zhang, J.; Arrington, J.; Bosted, P.; Bültmann, S.; Christy, M. E.; Dutta, D.; Ent, R.; Fenker, H.; Griffioen, K. A.; Ispiryan, M.; Kalantarians, N.; Keppel, C. E.; Melnitchouk, W.; Tvaskis, V.; Adhikari, K. P.; Aghasyan, M.; Amaryan, M. J.; Anefalos Pereira, S.; Avakian, H.; Ball, J.; Baltzell, N. A.; Battaglieri, M.; Bedlinskiy, I.; Biselli, A. S.; Briscoe, W. J.; Brooks, W. K.; Burkert, V. D.; Carman, D. S.; Celentano, A.; Chandavar, S.; Charles, G.; Cole, P. L.; Contalbrigo, M.; Cortes, O.; Crede, V.; D'Angelo, A.; Dashyan, N.; De Vita, R.; De Sanctis, E.; Deur, A.; Djalali, C.; Dodge, G. E.; Doughty, D.; Dupre, R.; Egiyan, H.; El Alaoui, A.; El Fassi, L.; Elouadrhiri, L.; Eugenio, P.; Fedotov, G.; Fleming, J. A.; Garillon, B.; Gevorgyan, N.; Ghandilyan, Y.; Gilfoyle, G. P.; Giovanetti, K. L.; Girod, F. X.; Goetz, J. T.; Golovatch, E.; Gothe, R. W.; Guidal, M.; Guo, L.; Hafidi, K.; Hakobyan, H.; Hanretty, C.; Harrison, N.; Hattawy, M.; Hicks, K.; Ho, D.; Holtrop, M.; Hyde, C. E.; Ilieva, Y.; Ireland, D. G.; Ishkhanov, B. S.; Jo, H. S.; Keller, D.; Khandaker, M.; Kim, A.; Kim, W.; King, P. M.; Klein, A.; Klein, F. J.; Koirala, S.; Kubarovsky, V.; Kuleshov, S. V.; Lenisa, P.; Lewis, S.; Livingston, K.; Lu, H.; MacCormick, M.; MacGregor, I. J. D.; Markov, N.; Mayer, M.; McKinnon, B.; Mineeva, T.; Mirazita, M.; Mokeev, V.; Montgomery, R. A.; Moutarde, H.; Munoz Camacho, C.; Nadel-Turonski, P.; Niccolai, S.; Niculescu, G.; Niculescu, I.; Osipenko, M.; Pappalardo, L. L.; Paremuzyan, R.; Park, K.; Pasyuk, E.; Phillips, J. J.; Pisano, S.; Pogorelko, O.; Pozdniakov, S.; Price, J. W.; Procureur, S.; Protopopescu, D.; Puckett, A. J. R.; Rimal, D.; Ripani, M.; Rizzo, A.; Rosner, G.; Rossi, P.; Roy, P.; Sabatié, F.; Schott, D.; Schumacher, R. A.; Seder, E.; Senderovich, I.; Sharabian, Y. G.; Simonyan, A.; Smith, G. D.; Sober, D. I.; Sokhan, D.; Stepanyan, S.; Stepanyan, S. S.; Strauch, S.; Tang, W.; Ungaro, M.; Vlassov, A. V.; Voskanyan, H.; Voutier, E.; Walford, N. K.; Watts, D.; Wei, X.; Weinstein, L. B.; Wood, M. H.; Zana, L.; Zonta, I.

    2014-04-24

    In this study, much less is known about neutron structure than that of the proton due to the absence of free neutron targets. Neutron information is usually extracted from data on nuclear targets such as deuterium, requiring corrections for nuclear binding and nucleon off-shell effects. These corrections are model dependent and have significant uncertainties, especially for large values of the Bjorken scaling variable x. As a consequence, the same data can lead to different conclusions, for example, about the behavior of the d quark distribution in the proton at large x.

  9. Observation of <mi>D>0 meson nuclear modifications in <mi>Au+Au> collisions at <mi>smi><mi>NN>=200 <mi>GeV>

    SciTech Connect (OSTI)

    Adamczyk, L.; Adkins, J.?K.; Agakishiev, G.; Aggarwal, M.?M.; Ahammed, Z.; Alekseev, I.; Alford, J.; Anson, C.?D.; Aparin, A.; Arkhipkin, D.; Aschenauer, E.?C.; Averichev, G.?S.; Banerjee, A.; Beavis, D.?R.; Bellwied, R.; Bhasin, A.; Bhati, A.?K.; Bhattarai, P.; Bichsel, H.; Bielcik, J.; Bielcikova, J.; Bland, L.?C.; Bordyuzhin, I.?G.; Borowski, W.; Bouchet, J.; Brandin, A.?V.; Brovko, S.?G.; Bültmann, S.; Bunzarov, I.; Burton, T.?P.; Butterworth, J.; Caines, H.; Calderón de la Barca Sánchez, M.; Cebra, D.; Cendejas, R.; Cervantes, M.?C.; Chaloupka, P.; Chang, Z.; Chattopadhyay, S.; Chen, H.?F.; Chen, J.?H.; Chen, L.; Cheng, J.; Cherney, M.; Chikanian, A.; Christie, W.; Chwastowski, J.; Codrington, M.?J.?M.; Contin, G.; Cramer, J.?G.; Crawford, H.?J.; Cui, X.; Das, S.; Davila Leyva, A.; De Silva, L.?C.; Debbe, R.?R.; Dedovich, T.?G.; Deng, J.; Derevschikov, A.?A.; Derradi de Souza, R.; Dhamija, S.; di Ruzza, B.; Didenko, L.; Dilks, C.; Ding, F.; Djawotho, P.; Dong, X.; Drachenberg, J.?L.; Draper, J.?E.; Du, C.?M.; Dunkelberger, L.?E.; Dunlop, J.?C.; Efimov, L.?G.; Engelage, J.; Engle, K.?S.; Eppley, G.; Eun, L.; Evdokimov, O.; Eyser, O.; Fatemi, R.; Fazio, S.; Fedorisin, J.; Filip, P.; Finch, E.; Fisyak, Y.; Flores, C.?E.; Gagliardi, C.?A.; Gangadharan, D.?R.; Garand, D.; Geurts, F.; Gibson, A.; Girard, M.; Gliske, S.; Greiner, L.; Grosnick, D.; Gunarathne, D.?S.; Guo, Y.; Gupta, A.; Gupta, S.; Guryn, W.; Haag, B.; Hamed, A.; Han, L.-X.; Haque, R.; Harris, J.?W.; Heppelmann, S.; Hirsch, A.; Hoffmann, G.?W.; Hofman, D.?J.; Horvat, S.; Huang, B.; Huang, H.?Z.; Huang, X.; Huck, P.; Humanic, T.?J.; Igo, G.; Jacobs, W.?W.; Jang, H.; Judd, E.?G.; Kabana, S.; Kalinkin, D.; Kang, K.; Kauder, K.; Ke, H.?W.; Keane, D.; Kechechyan, A.; Kesich, A.; Khan, Z.?H.; Kikola, D.?P.; Kisel, I.; Kisiel, A.; Koetke, D.?D.; Kollegger, T.; Konzer, J.; Koralt, I.; Kotchenda, L.; Kraishan, A.?F.; Kravtsov, P.; Krueger, K.; Kulakov, I.; Kumar, L.; Kycia, R.?A.; Lamont, M.?A.?C.; Landgraf, J.?M.; Landry, K.?D.; Lauret, J.; Lebedev, A.; Lednicky, R.; Lee, J.?H.; LeVine, M.?J.; Li, C.; Li, W.; Li, X.; Li, X.; Li, Y.; Li, Z.?M.; Lisa, M.?A.; Liu, F.; Ljubicic, T.; Llope, W.?J.; Lomnitz, M.; Longacre, R.?S.; Luo, X.; Ma, G.?L.; Ma, Y.?G.; Madagodagettige Don, D.?M.?M.?D.; Mahapatra, D.?P.; Majka, R.; Margetis, S.; Markert, C.; Masui, H.; Matis, H.?S.; McDonald, D.; McShane, T.?S.; Minaev, N.?G.; Mioduszewski, S.; Mohanty, B.; Mondal, M.?M.; Morozov, D.?A.; Mustafa, M.?K.; Nandi, B.?K.; Nasim, Md.; Nayak, T.?K.; Nelson, J.?M.; Nigmatkulov, G.; Nogach, L.?V.; Noh, S.?Y.; Novak, J.; Nurushev, S.?B.; Odyniec, G.; Ogawa, A.; Oh, K.; Ohlson, A.; Okorokov, V.; Oldag, E.?W.; Olvitt, D.?L.; Pachr, M.; Page, B.?S.; Pal, S.?K.; Pan, Y.?X.; Pandit, Y.; Panebratsev, Y.; Pawlak, T.; Pawlik, B.; Pei, H.; Perkins, C.; Peryt, W.; Pile, P.; Planinic, M.; Pluta, J.; Poljak, N.; Porter, J.; Poskanzer, A.?M.; Pruthi, N.?K.; Przybycien, M.; Pujahari, P.?R.; Putschke, J.; Qiu, H.; Quintero, A.; Ramachandran, S.; Raniwala, R.; Raniwala, S.; Ray, R.?L.; Riley, C.?K.; Ritter, H.?G.; Roberts, J.?B.; Rogachevskiy, O.?V.; Romero, J.?L.; Ross, J.?F.; Roy, A.; Ruan, L.; Rusnak, J.; Rusnakova, O.; Sahoo, N.?R.; Sahu, P.?K.; Sakrejda, I.; Salur, S.; Sandweiss, J.; Sangaline, E.; Sarkar, A.; Schambach, J.; Scharenberg, R.?P.; Schmah, A.?M.; Schmidke, W.?B.; Schmitz, N.; Seger, J.; Seyboth, P.; Shah, N.; Shahaliev, E.; Shanmuganathan, P.?V.; Shao, M.; Sharma, B.; Shen, W.?Q.; Shi, S.?S.; Shou, Q.?Y.; Sichtermann, E.?P.; Singaraju, R.?N.; Skoby, M.?J.; Smirnov, D.; Smirnov, N.; Solanki, D.; Sorensen, P.; Spinka, H.?M.; Srivastava, B.; Stanislaus, T.?D.?S.; Stevens, J.?R.; Stock, R.; Strikhanov, M.; Stringfellow, B.; Sumbera, M.; Sun, X.; Sun, X.?M.; Sun, Y.; Sun, Z.; Surrow, B.; Svirida, D.?N.; Symons, T.?J.?M.; Szelezniak, M.?A.; Takahashi, J.; Tang, A.?H.; Tang, Z.; Tarnowsky, T.; Thomas, J.?H.; Timmins, A.?R.; Tlusty, D.; Tokarev, M.; Trentalange, S.; Tribble, R.?E.; Tribedy, P.; Trzeciak, B.?A.; Tsai, O.?D.; Turnau, J.; Ullrich, T.; Underwood, D.?G.; Van Buren, G.; van Nieuwenhuizen, G.; Vandenbroucke, M.; Vanfossen, J.?A.; Varma, R.; Vasconcelos, G.?M.?S.; Vasiliev, A.?N.; Vertesi, R.; Videbæk, F.; Viyogi, Y.?P.; Vokal, S.; Vossen, A.; Wada, M.; Wang, F.; Wang, G.; Wang, H.; Wang, J.?S.; Wang, X.?L.; Wang, Y.; Wang, Y.; Webb, G.; Webb, J.?C.; Westfall, G.?D.; Wieman, H.; Wissink, S.?W.; Witt, R.; Wu, Y.?F.; Xiao, Z.; Xie, W.; Xin, K.; Xu, H.; Xu, J.; Xu, N.

    2014-09-30

    We report the first measurement of charmed-hadron (D0) production via the hadronic decay channel (D0?K-+?+) in Au+Au collisions at ?sNN=200 GeV with the STAR experiment. The charm production cross section per nucleon-nucleon collision at midrapidity scales with the number of binary collisions, Nbin, from p+p to central Au+Au collisions. The D0 meson yields in central Au+Aucollisions are strongly suppressed compared to those in p+p scaled by Nbin, for transverse momenta pT>3 GeV/c, demonstrating significant energy loss of charm quarks in the hot and dense medium. An enhancement at intermediate pT is also observed. Model calculations including strong charm-medium interactions and coalescence hadronization describe our measurements.

  10. Global Warming in Geologic Time

    SciTech Connect (OSTI)

    Archer, David

    2008-02-27

    The notion is pervasive in the climate science community and in the public at large that the climate impacts of fossil fuel CO2 release will only persist for a few centuries. This conclusion has no basis in theory or models of the atmosphere/ ocean carbon cycle, which we review here. The largest fraction of the CO2 recovery will take place on time scales of centuries, as CO2 invades the ocean, but a significant fraction of the fossil fuel CO2, ranging in published models in the literature from 20-60%, remains airborne for a thousand years or longer. Ultimate recovery takes place on time scales of hundreds of thousands of years, a geologic longevity typically associated in public perceptions with nuclear waste. The glacial/interglacial climate cycles demonstrate that ice sheets and sea level respond dramatically to millennial-timescale changes in climate forcing. There are also potential positive feedbacks in the carbon cycle, including methane hydrates in the ocean, and peat frozen in permafrost, that are most sensitive to the long tail of the fossil fuel CO2 in the atmosphere.

  11. Global Warming in Geologic Time

    SciTech Connect (OSTI)

    David Archer

    2008-02-27

    The notion is pervasive in the climate science community and in the public at large that the climate impacts of fossil fuel CO2 release will only persist for a few centuries. This conclusion has no basis in theory or models of the atmosphere / ocean carbon cycle, which we review here. The largest fraction of the CO2 recovery will take place on time scales of centuries, as CO2 invades the ocean, but a significant fraction of the fossil fuel CO2, ranging in published models in the literature from 20-60%, remains airborne for a thousand years or longer. Ultimate recovery takes place on time scales of hundreds of thousands of years, a geologic longevity typically associated in public perceptions with nuclear waste. The glacial / interglacial climate cycles demonstrate that ice sheets and sea level respond dramatically to millennial-timescale changes in climate forcing. There are also potential positive feedbacks in the carbon cycle, including methane hydrates in the ocean, and peat frozen in permafrost, that are most sensitive to the long tail of the fossil fuel CO2 in the atmosphere.

  12. Global Warming in Geologic Time

    ScienceCinema (OSTI)

    David Archer

    2010-01-08

    The notion is pervasive in the climate science community and in the public at large that the climate impacts of fossil fuel CO2 release will only persist for a few centuries. This conclusion has no basis in theory or models of the atmosphere / ocean carbon cycle, which we review here. The largest fraction of the CO2 recovery will take place on time scales of centuries, as CO2 invades the ocean, but a significant fraction of the fossil fuel CO2, ranging in published models in the literature from 20-60%, remains airborne for a thousand years or longer. Ultimate recovery takes place on time scales of hundreds of thousands of years, a geologic longevity typically associated in public perceptions with nuclear waste. The glacial / interglacial climate cycles demonstrate that ice sheets and sea level respond dramatically to millennial-timescale changes in climate forcing. There are also potential positive feedbacks in the carbon cycle, including methane hydrates in the ocean, and peat frozen in permafrost, that are most sensitive to the long tail of the fossil fuel CO2 in the atmosphere.

  13. Real time analysis under EDS

    SciTech Connect (OSTI)

    Schneberk, D.

    1985-07-01

    This paper describes the analysis component of the Enrichment Diagnostic System (EDS) developed for the Atomic Vapor Laser Isotope Separation Program (AVLIS) at Lawrence Livermore National Laboratory (LLNL). Four different types of analysis are performed on data acquired through EDS: (1) absorption spectroscopy on laser-generated spectral lines, (2) mass spectrometer analysis, (3) general purpose waveform analysis, and (4) separation performance calculations. The information produced from this data includes: measures of particle density and velocity, partial pressures of residual gases, and overall measures of isotope enrichment. The analysis component supports a variety of real-time modeling tasks, a means for broadcasting data to other nodes, and a great degree of flexibility for tailoring computations to the exact needs of the process. A particular data base structure and program flow is common to all types of analysis. Key elements of the analysis component are: (1) a fast access data base which can configure all types of analysis, (2) a selected set of analysis routines, (3) a general purpose data manipulation and graphics package for the results of real time analysis. Each of these components are described with an emphasis upon how each contributes to overall system capability. 3 figs.

  14. Time Dependent Density Functional Theory An introduction

    E-Print Network [OSTI]

    Botti, Silvana

    Time Dependent Density Functional Theory An introduction Francesco Sottile LSI, Ecole Polytechnique (ETSF) Time Dependent Density Functional Theory Palaiseau, 7 February 2012 1 / 32 #12;Outline 1 Frontiers 4 Perspectives and Resources Francesco Sottile (ETSF) Time Dependent Density Functional Theory

  15. INVESTIGATION Genomic Background and Generation Time

    E-Print Network [OSTI]

    Lynch, Michael

    INVESTIGATION Genomic Background and Generation Time Influence Deleterious Mutation Rates variation is generated and how selection shapes mutation rates over evolutionary time requires knowledge, genomic background and generation time, on deleterious mutation in Daphnia pulicaria, a cyclically

  16. AUTOMATIC PROGRAM TIMING PROFILES WITH FTN4

    E-Print Network [OSTI]

    Friedman, Richard.

    2010-01-01

    September 22-25, 1980 AUTOMATIC PROGRAM TIMING PROFILES WITHW-7405-ENG-48 LBL-1l290 Automatic Program Timing ProfilesW-1405-ENG-48 LBL-11290 Automatic Program Timing Profiles

  17. Time Travel and the Reality of Spontaneity

    E-Print Network [OSTI]

    C. K. Raju

    2008-04-05

    Contrary to the informed consensus, time travel implies spontaneity (as distinct from chance) so that time travel can only be of the second kind.

  18. Time domain electromagnetic metal detectors

    SciTech Connect (OSTI)

    Hoekstra, P.

    1996-04-01

    This presentation focuses on illustrating by case histories the range of applications and limitations of time domain electromagnetic (TDEM) systems for buried metal detection. Advantages claimed for TDEM metal detectors are: independent of instrument response (Geonics EM61) to surrounding soil and rock type; simple anomaly shape; mitigation of interference by ambient electromagnetic noise; and responsive to both ferrous and non-ferrous metallic targets. The data in all case histories to be presented were acquired with the Geonics EM61 TDEM system. Case histories are a test bed site on Molokai, Hawaii; Fort Monroe, Virginia; and USDOE, Rocky Flats Plant. The present limitations of this technology are: discrimination capabilities in terms of type of ordnance, and depth of burial is limited, and ability of resolving targets with small metallic ambient needs to be improved.

  19. 274 Giltner Hall East Lansing, MI

    E-Print Network [OSTI]

    The Doctoral Specialization in Environmental Science and Policy allows a student to waive one of Requirements 2 (Interdisciplinary Environmental Natural Science and Policy) and Requirement 3 (Interdisciplinary Environmental. For the natural sciences, such experience might include physics or geology with chemistry and biology (ecology

  20. Marysville, MI Natural Gas Exports to Canada

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    4,925 22,198 41,964 42,866 35,273 24,583 1996-2014 Pipeline Prices 4.85 4.87 4.48 3.18 3.98 5.45 1996...