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  1. Sylvania Corporation, Hicksville, NY and Bayside NY | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Sylvania Corporation, Hicksville, NY and Bayside NY Sylvania Corporation, Hicksville, NY and Bayside NY Sylvania Corporation, Hicksville, NY and Bayside NY. Memorandumtoreader.pd...

  2. Sylvania Corporation, Hicksville, NY and Bayside, NY | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    NY Sylvania Corporation, Hicksville, NY and Bayside, NY Sylvania Corporation, Hicksville, NY and Bayside, NY, July 8, 2004. sylvaniacorporation.pdf PDF icon Sylvania Corporation, ...

  3. Sylvania Corporation, Hicksville, NY and Bayside, NY - Addendum...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    NY - Addendum to July 8, 2004 Sylvania Corporation, Hicksville, NY and Bayside, NY - Addendum to July 8, 2004 Sylvania Corporation, Hicksville, NY and Bayside, NY - Addendum to ...

  4. Business Council of Westchester County (NY) | Open Energy Information

    Open Energy Info (EERE)

    101 Place: White Plains, New York Zip: 10604 Region: Northeast - NY NJ CT PA Area Sector: Services Product: Green Power Marketer Website: www.westchesterny.org Coordinates:...

  5. Sylvania Corporation, Hicksville, NY and Bayside, NY - Addendum to July

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    8, 2004 | Department of Energy NY - Addendum to July 8, 2004 Sylvania Corporation, Hicksville, NY and Bayside, NY - Addendum to July 8, 2004 Sylvania Corporation, Hicksville, NY and Bayside, NY - Addendum to July 8, 2004, additional_sylvania.pdf memorandum Date: October 6, 2004 Reply to Attn of: Department of Energy Headquarters FOIA/Privacy Act Office Sylvania Corporation, Hicksville, NY and Bayside, NY - Addendum to July 8, 2004 (11.46 KB) More Documents & Publications Index2.doc

  6. NY-Sun Loan Program

    Office of Energy Efficiency and Renewable Energy (EERE)

    NY-Sun loan program is part of broader NY-Sun Initiative program to accelerate the use of solar PV across the State. In addition to cash incentives, NY-Sun Initiative also provides State sponsored...

  7. Renewable Heat NY

    Office of Energy Efficiency and Renewable Energy (EERE)

    NOTE: On August 2015, NYSERDA increased the incentive levels for technologies offered under the Renewable Heat NY program. In general, new incentives fund up to 45% of the total project cost, which...

  8. Analysis of natural gases, AL, AR, FL, GA, IL, IN, IA, KY, LA, MD, MI, MS, MO, NJ, NY, NC, OH, PA, TN, VA, and WV; 1951-1991 (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1991-01-01

    The U.S. Bureau of Mines diskette contains analysis and related source data for 2,357 natural gas samples collected from miscellaneous states, which include the following states: Alabama, Arkansas (except Arkoma Basin), Florida, Georgia, Illinois, Indiana, Iowa, Kentucky, Louisiana, Maryland, Michigan, Mississippi, Missouri, New Jersey, New York, North Carolina, Ohio, Pennsylvania, Tennessee, Virginia, and West Virginia. All samples were obtained and analyzed as part of the Bureau's investigations of occurrences of helium in natural gases of countries with free market economies. The survey has been conducted since 1917. The analysis contained on the diskette contain the full range of component analysis data. Five files are on the diskette: READ.ME, MISC.TXT, MISC.DBF, USHEANAL.DBF, and BASINCDE.TXT.

  9. Category:Syracuse, NY | Open Energy Information

    Open Energy Info (EERE)

    KB SVLargeOffice Syracuse NY Consolidated Edison Co-NY Inc.png SVLargeOffice Syracuse... 68 KB SVMediumOffice Syracuse NY Consolidated Edison Co-NY Inc.png SVMediumOffice...

  10. ACIM-~ NY.49

    Office of Legacy Management (LM)

    ' h:. ,,, ,_" , ACIM-~ NY.49 .,. i MEMORANDUM TO: FILE DATE FE: __~-tt_c~7' e_-_~-~------- --------- "%Kf-- ---- ---i------- Current: ~~~~~~--------__---_______ xf yee, date contacted- IVPE OF OPERATION f- ------------- Research & Development 0 Production scale testing 0 Pilot Scale 0 Bench Scale Process z Theoretical Studies Sample 84 Analysis 0 Production 0 Disposal/Storage a Facility Type 0 Manufacturing 0 University 0 Research Organization 0 Government Sponsored Fat a Other

  11. Category:Rochester, NY | Open Energy Information

    Open Energy Info (EERE)

    in this category, out of 16 total. SVFullServiceRestaurant Rochester NY Consolidated Edison Co-NY Inc.png SVFullServiceRestauran... 70 KB SVQuickServiceRestaurant Rochester NY...

  12. DOE - Office of Legacy Management -- Buffalo NY Site - NY 54

    Office of Legacy Management (LM)

    ... 19, 1992 NY.54-3 - U.S. Government (Tonawanda Sub-Office) Memorandum; Hershman to Smith; Subject: Transmittal of Monthly Progress Report for October, October 21, 1952. ...

  13. DOE - Office of Legacy Management -- Guterl Specialty Steel - NY 12

    Office of Legacy Management (LM)

    Guterl Specialty Steel - NY 12 FUSRAP Considered Sites Guterl Specialty Steel, NY Alternate Name(s): Simonds Saw and Steel Co. Guterl Steel Allegheny Ludlum Steel Corp. NY.12-1 NY.12-2 Location: Ohio Street and Route 95, Lockport, New York NY.12-12 Historical Operations: Performed rolling mill operations on natural uranium and thorium metal. NY.12-6 NY.12-7 Eligibility Determination: NY.12-11 Radiological Survey(s): Assessment Surveys NY.12-1 NY.12-4 NY.12-8 NY.12-9 NY.12-12 Site Status: Cleanup

  14. NY Solar Map and Portal

    Broader source: Energy.gov [DOE]

    The NY Solar Map and Portal helps New Yorkers determine the advantages of going solar by providing detailed and localized information about a customer's solar potential. Supported by the SunShot...

  15. Appendix PA: Performance Assessment

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    for the Waste Isolation Pilot Plant Appendix PA-2014 Performance Assessment United States Department of Energy Waste Isolation Pilot Plant Carlsbad Field Office Carlsbad, New Mexico Compliance Recertification Application 2014 Appendix PA Table of Contents PA-1.0 Introduction PA-1.1 Changes since the CRA-2009 PA PA-1.1.1 Replacement of Option D with the ROMPCS PA-1.1.2 Additional Mined Volume in the Repository North End PA-1.1.3 Refinement to the Probability of Encountering Pressurized Brine

  16. AER NY Kinetics LLC | Open Energy Information

    Open Energy Info (EERE)

    AER NY Kinetics LLC Jump to: navigation, search Name: AER NY Kinetics LLC Address: PO Box 585 21 Entrance Avenue Place: Ogdensburg Zip: 13669 Region: United States Sector: Marine...

  17. Western NY Energy LLC | Open Energy Information

    Open Energy Info (EERE)

    search Name: Western NY Energy LLC Place: Mount Morris, New York Zip: 14510 Product: Bioethanol producer. References: Western NY Energy LLC1 This article is a stub. You can help...

  18. Upstate NY Power Corp | Open Energy Information

    Open Energy Info (EERE)

    NY Power Corp Jump to: navigation, search Name: Upstate NY Power Corp Place: West Seneca, New York Zip: 14224-3454 Sector: Wind energy Product: Developer of clean energy projects...

  19. DOE - Office of Legacy Management -- Syracuse University - NY 29

    Office of Legacy Management (LM)

    Syracuse University - NY 29 FUSRAP Considered Sites Site: SYRACUSE UNIVERSITY (NY.29) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Syracuse , New York NY.29-1 Evaluation Year: 1994 NY.29-2 Site Operations: Activities included work with uranium oxide and the precipitation of thorium iodate from homogeneous solution. NY.29-1 NY.29-3 NY.29-4 Site Disposition: Eliminated - Potential for contamination remote NY.29-2 Radioactive Materials

  20. DOE - Office of Legacy Management -- Colonie - NY 06

    Office of Legacy Management (LM)

    Colonie - NY 06 FUSRAP Considered Sites Colonie, NY Alternate Name(s): Colonie Interim Storage Site National Lead Industries NY.06-1 Location: 1130 Central Avenue, Colonie, New York NY.06-1 Historical Operations: Fabricated and processed uranium metal for the AEC, resulting in contamination from thorium and natural, enriched, and depleted uranium. NY.06-1 NY.06-4 NY.06-5 Eligibility Determination: Eligible NY.06-2 NY.06-3 Radiological Survey(s): Assessment Surveys, Verification Surveys NY.06-6

  1. DOE - Office of Legacy Management -- Gleason Works - NY 55

    Office of Legacy Management (LM)

    Gleason Works - NY 55 FUSRAP Considered Sites Site: GLEASON WORKS (NY.55 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Rochester , New York NY.55-1 Evaluation Year: 1994 NY.55-2 Site Operations: Metal fabrication operations - Rolled uranium metal. NY.55-1 Site Disposition: Eliminated - Potential for contamination considered remote NY.55-2 Radioactive Materials Handled: Yes Primary Radioactive Materials Handled: Uranium NY.55-1

  2. DOE - Office of Legacy Management -- Hooker Chemical Co - NY 05

    Office of Legacy Management (LM)

    Hooker Chemical Co - NY 05 FUSRAP Considered Sites Site: Hooker Chemical Co. (NY.05) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: Occidental Chemical Corporation Hooker Electrochemical Corporation NY.05-1 NY.05-2 Location: Niagara Falls , New York NY.05-3 Evaluation Year: 1985 NY.05-1 NY.05-2 Site Operations: Design, engineering, construction, equipping and operation of a plant for the manufacture of Product 45 (xylene hexachloride); MFL (Miller's

  3. NY_8076404_nightfall.jpg | OSTI, US Dept of Energy Office of Scientific and

    Office of Scientific and Technical Information (OSTI)

    Technical Information NY_8076404_nightfall

  4. NY Green Bank | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    sector to address and alleviate market and financial barriers preventing a thriving clean energy marketplace. NY Green Bank does not accept deposits or offer retail loans, and...

  5. DOE - Office of Legacy Management -- ACF Industries Inc - NY...

    Office of Legacy Management (LM)

    No radioactive materials used at the site. NY.13-2 Site Disposition: Eliminated - Declared clean by AEC and returned to the prime tenant NY.13-1 NY.13-3 Radioactive Materials ...

  6. NY

    Office of Legacy Management (LM)

    ... Knolls Atomic Power Laboratory (KAPL). Receipt of radioactive waete was diecontinued in ... Confi'metion of January la8l Survey Reeults Ganrna-Ray Exposure Rates The expoeure rateo ...

  7. DOE - Office of Legacy Management -- Columbia University - NY 03

    Office of Legacy Management (LM)

    Columbia University - NY 03 FUSRAP Considered Sites Site: Columbia University (NY.03 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: New York , New York NY.03-1 Evaluation Year: 1985 NY.03-2 NY.03-3 Site Operations: Early research and development -- nuclear chain reaction (fission) and gaseous diffusion during the 1940s. NY.03-4 Site Disposition: Eliminated - Radiation levels below criteria - Indication of university sponsored

  8. DOE - Office of Legacy Management -- Markite Co - NY 49

    Office of Legacy Management (LM)

    Markite Co - NY 49 FUSRAP Considered Sites Site: MARKITE CO. (NY.49 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: 155 Waverly Place , New York , New York NY.49-1 Evaluation Year: 1987 NY.49-2 Site Operations: Conducted experiments with very small amounts of uranium and thorium. NY.49-2 Site Disposition: Eliminated - Handled limited amounts of radioactive materials - Potential for contamination remote NY.49-2 Radioactive Materials

  9. US MidAtl NY Site Consumption

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    MidAtl NY Site Consumption million Btu 0 500 1,000 1,500 2,000 2,500 3,000 US ... 8,000 10,000 12,000 US MidAtl NY Site Consumption kilowatthours 0 250 500 750 1,000 ...

  10. New York Battery and Energy Storage Technology Consortium NY...

    Open Energy Info (EERE)

    Battery and Energy Storage Technology Consortium NY BEST Jump to: navigation, search Name: New York Battery and Energy Storage Technology Consortium (NY-BEST) Place: Albany, New...

  11. DOE - Office of Legacy Management -- National Carbon Co - NY 48

    Office of Legacy Management (LM)

    Carbon Co - NY 48 FUSRAP Considered Sites Site: NATIONAL CARBON CO (NY.48) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: New York , New York NY.48-1 Evaluation Year: 1987 NY.48-2 Site Operations: Produced graphite for the MED/AEC. NY.48-1 NY.48-2 NY.48-3 Site Disposition: Eliminated - Potential for residual radioactive contamination considered remote - No indication that radioactive material was used on the site NY.48-2 Radioactive

  12. DOE - Office of Legacy Management -- New York University - NY 50

    Office of Legacy Management (LM)

    University - NY 50 FUSRAP Considered Sites Site: NEW YORK UNIVERSITY (NY.50) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: New York , New York NY.50-1 Evaluation Year: 1987 NY.50-1 Site Operations: Activities were related to equipment development. Counters and a small quantity of uranium oxide were provided by the AEC for work under contract AT(30-1)-1256. NY.50-2 NY.50-3 NY.50-4 NY.50-1 Site Disposition: Eliminated - Potential for

  13. DOE - Office of Legacy Management -- American Railway Express Office - NY

    Office of Legacy Management (LM)

    0-03 Railway Express Office - NY 0-03 FUSRAP Considered Sites Site: American Railway Express Office (NY.0-03 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: American Railway Express (Downtown) , New York , New York NY.0-03-1 Evaluation Year: 1987 NY.0-03-1 Site Operations: None - Involved with a fire during transport of uranium scrap. NY.0-03-2 Site Disposition: Eliminated - Potential for contamination remote NY.0-03-1 NY.0-03-2

  14. DOE - Office of Legacy Management -- Electromet Corporation - NY 04

    Office of Legacy Management (LM)

    Electromet Corporation - NY 04 FUSRAP Considered Sites Site: Electromet Corporation (NY.04 ) Eliminated from consideration under FUSRAP - Referred to US EPA and New York State Designated Name: Not Designated Alternate Name: None Location: 4625 Royal Avenue , Niagara Falls , New York NY.04-1 Evaluation Year: 1985 NY.04-2 NY.04-3 Site Operations: Cast zirconium sponge into ingots in the 1950s. NY.04-4 Site Disposition: Eliminated - No Authority NY.04-2 Radioactive Materials Handled: Yes Primary

  15. DOE - Office of Legacy Management -- Seaway Industrial Park - NY 09

    Office of Legacy Management (LM)

    Seaway Industrial Park - NY 09 FUSRAP Considered Sites Seaway Industrial Park, NY Alternate Name(s): Seaway Industrial Landfill Seaway Landfill Charles St. Plant NY.09-2 NY.09-3 Location: River Road, Tonawanda, New York NY.09-4 Historical Operations: Received approximately 6,000 cubic yards of low-grade uranium mill tailings and processing residues from the Ashland (Tonawanda North Units 1 and 2) sites. NY.09-5 Eligibility Determination: Eligible NY.09-1 Radiological Survey(s): Assessment

  16. DOE - Office of Legacy Management -- Sylvania Corning Plant - NY 19

    Office of Legacy Management (LM)

    Plant - NY 19 FUSRAP Considered Sites Sylvania-Corning, NY Alternate Name(s): Sylvania Electric Products, Inc. Sylvania Corp. NY.19-1 NY.19-4 Location: Cantiaque Road, Hicksville, Long Island, New York NY.19-5 Historical Operations: Pilot-scale production of powdered metal uranium slugs for AEC's Hanford reactor. NY.19-4 Eligibility Determination: Eligible Radiological Survey(s): Assessment Survey NY.19-3 Site Status: Cleanup in progress by U.S. Army Corps of Engineers. USACE Website Long-term

  17. DOE - Office of Legacy Management -- Buflovak Co - NY 56

    Office of Legacy Management (LM)

    Buflovak Co - NY 56 FUSRAP Considered Sites Site: Buflovak Co. (NY.56 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: 1543 Fillmore Ave. , Buffalo , New York NY.56-1 Evaluation Year: 1991 NY.56-2 Site Operations: Research and testing with uranium raffinate. NY.56-1 Site Disposition: Eliminated - Possibility for contamination considered remote due to scope of tests conducted and indication of cleanup operations after tests

  18. DOE - Office of Legacy Management -- Polytechnic Institute of Brooklyn - NY

    Office of Legacy Management (LM)

    0-19 Polytechnic Institute of Brooklyn - NY 0-19 FUSRAP Considered Sites Site: NY.0-19 (POLYTECHNIC INSTITUTE OF BROOKLYN) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: New York , New York NY.0-19-1 Evaluation Year: 1987 NY.0-19-1 Site Operations: Research and development involving only small quantities of radiological material in a controlled environment. NY.0-19-1 Site Disposition: Eliminated - Potential for contamination remote

  19. DOE - Office of Legacy Management -- Radiation Applications Inc - NY 57

    Office of Legacy Management (LM)

    Radiation Applications Inc - NY 57 FUSRAP Considered Sites Site: RADIATION APPLICATIONS, INC. ( NY.57 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: RAI NY.57-1 Location: 370 Lexington Avenue , New York , New York NY.57-3 Evaluation Year: 1991 NY.57-4 Site Operations: Developed foam separation techniques and proposed investigations to remove cesium and strontium from fission product waste solutions. No indication that a substantial quantity of

  20. DOE - Office of Legacy Management -- Sacandaga - NY 51

    Office of Legacy Management (LM)

    Sacandaga - NY 51 FUSRAP Considered Sites Site: SACANDAGA (NY.51) Eliminated - Condition certified Designated Name: Not Designated Alternate Name: None Location: 823 Sacandaga Road , Glenville , New York NY.51-1 Evaluation Year: 1992 NY.51-2 Site Operations: Plant operated by General Electric during period spanning 1947 to 1951. Facilities housed studies involving radar, physics studies and sodium technology development. NY.51-1 Site Disposition: Eliminated - Radiation levels below criteria

  1. DOE - Office of Legacy Management -- Staten Island Warehouse - NY 22

    Office of Legacy Management (LM)

    Staten Island Warehouse - NY 22 FUSRAP Considered Sites Staten Island Warehouse, NY Alternate Name(s): Archer-Daniels Midland Company NY.22-3 Location: 2393 Richmond Terrace, Port Richmond, New York NY.22-2 Historical Operations: Stored pitchblende (high-grade uranium ore), which was purchased by the MED for the first atomic bomb. NY.22-3 Eligibility Determination: Eligible Radiological Survey(s): Assessment Survey NY.22-5 Site Status: Referred by DOE, evaluation in progess by U.S. Army Corps of

  2. DOE - Office of Legacy Management -- Love Canal - NY 24

    Office of Legacy Management (LM)

    NY.24-1 - DOE MemorandumChecklist; Jones to File; Subject: Elimination - Love Canal; April 30, 1987 NY.24-3 - Report; Smith to Fink; Preliminary Report of New York State Assembly ...

  3. DOE - Office of Legacy Management -- Ledoux and Co - NY 37

    Office of Legacy Management (LM)

    Ledoux and Co - NY 37 FUSRAP Considered Sites Site: LEDOUX AND CO. (NY.37 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: 155 Avenue of the Americas , New York , New York NY.37-1 Evaluation Year: 1987 NY.37-1 Site Operations: Prime contractor to AEC, African Metals. LeDoux handled radioactive materials under this contract at other locations; records indicate that radioactive materials were not sent to the New York office.

  4. DOE - Office of Legacy Management -- Rensselaer Polytechnic Institute - NY

    Office of Legacy Management (LM)

    18 Rensselaer Polytechnic Institute - NY 18 Site ID (CSD Index Number): NY.18 Site Name: RENSSELAER POLYTECHNIC INSTITUTE Site Summary: Site Link: External Site Link: Alternate Name(s): None Alternate Name Documents: Location: Troy , New York Location Documents: NY.18-1 Historical Operations (describe contaminants): Research activities involving small quantities of radioactive materials in a controlled environment - under AEC license. Historical Operations Documents: NY.18-1 Eligibility

  5. DOE - Office of Legacy Management -- Seneca Army Depot - NY 11

    Office of Legacy Management (LM)

    Seneca Army Depot - NY 11 FUSRAP Considered Sites Site: SENECA ARMY DEPOT (NY.11 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Romulus , New York Evaluation Year: 1985 NY.11-2 NY.11-3 Site Operations: Eleven bunkers were used to store approximately 2,000 drums of pitchblende ore in the early 1940's. The bunkers were returned to munitions storage service after removal of the ore drums. NY.11-4 Site Disposition: Eliminated - Referred to

  6. A5 PA Addendum 1

    National Nuclear Security Administration (NNSA)

    Performance Assessment for the Area 5 Radioactive Waste Management Site at the Nevada Test ... Nevada Operations Office NTS Nevada Test Site PA Performance Assessment RWMS ...

  7. NlZWYORK4,N.Y.

    Office of Legacy Management (LM)

    AFRICAN .METALS~ C~RPO~~XON 41 BROAD STREET . i. ,,J iI: : LE OCT 2 2 1945 NlZWYORK4,N.Y. :October 5, 1945. Af-2-a L.: I.__: '../ . ._ The Area Engineer, U.S. Engineer Office, P.O. BOX 42, Station F., New York 16, N.Y. Gentlemen: Contract W-7405 eng-4. Reference is made to your letter EIDM A-33 MS of August 27th, 1945. Contract W-7405 eng-4 called for the delivery of 100 T of M-31, the M308 content of which was sold to you, whereas we reserved all rights to the R-l contained therein. We hereby

  8. DOE - Office of Legacy Management -- American Machine and Foundry Co - NY

    Office of Legacy Management (LM)

    26 NY 26 FUSRAP Considered Sites Site: American Machine and Foundry Co ( NY.26 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: Lutheran Medical Center NY.26-1 Location: Second Avenue and 56th Street , Brooklyn , New York NY.26-2 Evaluation Year: 1992 NY.26-1 Site Operations: 1951 - 1954 conducted metal fabrication operation on uranium and thorium metals. NY.26-3 NY.26-4 Site Disposition: Eliminated - Potential for contamination considered remote

  9. Measurement of the direct <mi>CP> -violating parameter <mi>Ami><mi>CP> in the decay <mi>D>+<mi>Kmi>-<mimi>+<mi>π>+

    SciTech Connect (OSTI)

    Abazov, V. M.; Abbott, B.; Acharya, B. S.; Adams, M.; Adams, T.; Agnew, J. P.; Alexeev, G. D.; Alkhazov, G.; Alton, A.; Askew, A.; Atkins, S.; Augsten, K.; Avila, C.; Badaud, F.; Bagby, L.; Baldin, B.; Bandurin, D. V.; Banerjee, S.; Barberis, E.; Baringer, P.; Bartlett, J. F.; Bassler, U.; Bazterra, V.; Bean, A.; Begalli, M.; Bellantoni, L.; Beri, S. B.; Bernardi, G.; Bernhard, R.; Bertram, I.; Besançon, M.; Beuselinck, R.; Bhat, P. C.; Bhatia, S.; Bhatnagar, V.; Blazey, G.; Blessing, S.; Bloom, K.; Boehnlein, A.; Boline, D.; Boos, E. E.; Borissov, G.; Borysova, M.; Brandt, A.; Brandt, O.; Brock, R.; Bross, A.; Brown, D.; Bu, X. B.; Buehler, M.; Buescher, V.; Bunichev, V.; Burdin, S.; Buszello, C. P.; Camacho-Pérez, E.; Casey, B. C. K.; Castilla-Valdez, H.; Caughron, S.; Chakrabarti, S.; Chan, K. M.; Chandra, A.; Chapon, E.; Chen, G.; Cho, S. W.; Choi, S.; Choudhary, B.; Cihangir, S.; Claes, D.; Clutter, J.; Cooke, M.; Cooper, W. E.; Corcoran, M.; Couderc, F.; Cousinou, M. -C.; Cutts, D.; Das, A.; Davies, G.; de Jong, S. J.; De La Cruz-Burelo, E.; Déliot, F.; Demina, R.; Denisov, D.; Denisov, S. P.; Desai, S.; Deterre, C.; DeVaughan, K.; Diehl, H. T.; Diesburg, M.; Ding, P. F.; Dominguez, A.; Dubey, A.; Dudko, L. V.; Duperrin, A.; Dutt, S.; Eads, M.; Edmunds, D.; Ellison, J.; Elvira, V. D.; Enari, Y.; Evans, H.; Evdokimov, V. N.; Fauré, A.; Feng, L.; Ferbel, T.; Fiedler, F.; Filthaut, F.; Fisher, W.; Fisk, H. E.; Fortner, M.; Fox, H.; Fuess, S.; Garbincius, P. H.; Garcia-Bellido, A.; García-González, J. A.; Gavrilov, V.; Geng, W.; Gerber, C. E.; Gershtein, Y.; Ginther, G.; Gogota, O.; Golovanov, G.; Grannis, P. D.; Greder, S.; Greenlee, H.; Grenier, G.; Gris, Ph.; Grivaz, J. -F.; Grohsjean, A.; Grünendahl, S.; Grünewald, M. W.; Guillemin, T.; Gutierrez, G.; Gutierrez, P.; Haley, J.; Han, L.; Harder, K.; Harel, A.; Hauptman, J. M.; Hays, J.; Head, T.; Hebbeker, T.; Hedin, D.; Hegab, H.; Heinson, A. P.; Heintz, U.; Hensel, C.; Heredia-De La Cruz, I.; Herner, K.; Hesketh, G.; Hildreth, M. D.; Hirosky, R.; Hoang, T.; Hobbs, J. D.; Hoeneisen, B.; Hogan, J.; Hohlfeld, M.; Holzbauer, J. L.; Howley, I.; Hubacek, Z.; Hynek, V.; Iashvili, I.; Ilchenko, Y.; Illingworth, R.; Ito, A. S.; Jabeen, S.; Jaffré, M.; Jayasinghe, A.; Jeong, M. S.; Jesik, R.; Jiang, P.; Johns, K.; Johnson, E.; Johnson, M.; Jonckheere, A.; Jonsson, P.; Joshi, J.; Jung, A. W.; Juste, A.; Kajfasz, E.; Karmanov, D.; Katsanos, I.; Kaur, M.; Kehoe, R.; Kermiche, S.; Khalatyan, N.; Khanov, A.; Kharchilava, A.; Kharzheev, Y. N.; Kiselevich, I.; Kohli, J. M.; Kozelov, A. V.; Kraus, J.; Kumar, A.; Kupco, A.; Kurča, T.; Kuzmin, V. A.; Lammers, S.; Lebrun, P.; Lee, H. S.; Lee, S. W.; Lee, W. M.; Lei, X.; Lellouch, J.; Li, D.; Li, H.; Li, L.; Li, Q. Z.; Lim, J. K.; Lincoln, D.; Linnemann, J.; Lipaev, V. V.; Lipton, R.; Liu, H.; Liu, Y.; Lobodenko, A.; Lokajicek, M.; Lopes de Sa, R.; Luna-Garcia, R.; Lyon, A. L.; Maciel, A. K. A.; Madar, R.; Magaña-Villalba, R.; Malik, S.; Malyshev, V. L.; Mansour, J.; Martínez-Ortega, J.; McCarthy, R.; McGivern, C. L.; Meijer, M. M.; Melnitchouk, A.; Menezes, D.; Mercadante, P. G.; Merkin, M.; Meyer, A.; Meyer, J.; Miconi, F.; Mondal, N. K.; Mulhearn, M.; Nagy, E.; Narain, M.; Nayyar, R.; Neal, H. A.; Negret, J. P.; Neustroev, P.; Nguyen, H. T.; Nunnemann, T.; Orduna, J.; Osman, N.; Osta, J.; Pal, A.; Parashar, N.; Parihar, V.; Park, S. K.; Partridge, R.; Parua, N.; Patwa, A.; Penning, B.; Perfilov, M.; Peters, Y.; Petridis, K.; Petrillo, G.; Pétroff, P.; Pleier, M. -A.; Podstavkov, V. M.; Popov, A. V.; Prewitt, M.; Price, D.; Prokopenko, N.; Qian, J.; Quadt, A.; Quinn, B.; Ratoff, P. N.; Razumov, I.; Ripp-Baudot, I.; Rizatdinova, F.; Rominsky, M.; Ross, A.; Royon, C.; Rubinov, P.; Ruchti, R.; Sajot, G.; Sánchez-Hernández, A.; Sanders, M. P.; Santos, A. S.; Savage, G.; Savitskyi, M.; Sawyer, L.; Scanlon, T.; Schamberger, R. D.; Scheglov, Y.; Schellman, H.; Schwanenberger, C.; Schwienhorst, R.; Sekaric, J.; Severini, H.; Shabalina, E.; Shary, V.; Shaw, S.; Shchukin, A. A.; Simak, V.; Skubic, P.; Slattery, P.; Smirnov, D.; Snow, G. R.; Snow, J.; Snyder, S.; Söldner-Rembold, S.; Sonnenschein, L.; Soustruznik, K.; Stark, J.; Stoyanova, D. A.; Strauss, M.; Suter, L.; Svoisky, P.; Titov, M.; Tokmenin, V. V.; Tsai, Y. -T.; Tsybychev, D.; Tuchming, B.; Tully, C.; Uvarov, L.; Uvarov, S.; Uzunyan, S.; Van Kooten, R.; van Leeuwen, W. M.; Varelas, N.; Varnes, E. W.; Vasilyev, I. A.; Verkheev, A. Y.; Vertogradov, L. S.; Verzocchi, M.; Vesterinen, M.; Vilanova, D.; Vokac, P.; Wahl, H. D.; Wang, M. H. L. S.; Warchol, J.; Watts, G.; Wayne, M.; Weichert, J.; Welty-Rieger, L.; Williams, M. R. J.; Wilson, G. W.; Wobisch, M.; Wood, D. R.; Wyatt, T. R.; Xie, Y.; Yamada, R.; Yang, S.; Yasuda, T.; Yatsunenko, Y. A.; Ye, W.; Ye, Z.; Yin, H.; Yip, K.; Youn, S. W.; Yu, J. M.; Zennamo, J.; Zhao, T. G.; Zhou, B.; Zhu, J.; Zielinski, M.; Zieminska, D.; Zivkovic, L.

    2014-12-01

    We measure the direct mi>Cmi>mi>P>-violating parameter mi>Ami>mi>Cmi>mi>Pmi> for the decay of the charged charm meson, mi>Dmi>+mi>Kmi>-mi>πmi>+mi>πmi>+ (and charge conjugate), using the full 10.4 mi>fbmi>-1 sample of mi>p>mi>p>¯ collisions at mi>smi>=1.96 mi>TeVmi> collected by the D0 detector at the Fermilab Tevatron collider. We extract the raw reconstructed charge asymmetry by fitting the invariant mass distributions for the sum and difference of charge-specific samples. This quantity is then corrected for detector-related asymmetries using data-driven methods and for possible physics asymmetries (from mi>B>mi>D

  10. DOE - Office of Legacy Management -- Springdale PA - PA 11

    Office of Legacy Management (LM)

    FACT SHEET This fact sheet provides information about the Springdale, Pennsylvania, Site. This site is managed by the U.S. Department of Energy Office of Legacy Management. PA.11-1 ...

  11. PaR-PaR Laboratory Automation Platform

    SciTech Connect (OSTI)

    Linshiz, G; Stawski, N; Poust, S; Bi, CH; Keasling, JD; Hilson, NJ

    2013-05-01

    Labor-intensive multistep biological tasks, such as the construction and cloning of DNA molecules, are prime candidates for laboratory automation. Flexible and biology-friendly operation of robotic equipment is key to its successful integration in biological laboratories, and the efforts required to operate a robot must be much smaller than the alternative manual lab work. To achieve these goals, a simple high-level biology-friendly robot programming language is needed. We have developed and experimentally validated such a language: Programming a Robot (PaR-PaR). The syntax and compiler for the language are based on computer science principles and a deep understanding of biological workflows. PaR-PaR allows researchers to use liquid-handling robots effectively, enabling experiments that would not have been considered previously. After minimal training, a biologist can independently write complicated protocols for a robot within an hour. Adoption of PaR-PaR as a standard cross-platform language would enable hand-written or software-generated robotic protocols to be shared across laboratories.

  12. Mr. Shaun Maloney :

    Office of Legacy Management (LM)

    ... Detroit, MI 48232 Chambersburg Engineering Co. Chambersburg, PA Ithaca Gun Co. Ithaca, NY New England Materials Lab., Inc. Teledyne Materials' . Medford, MA NRC Equipment Co. . -. ...

  13. NY-Sun PV Incentive Program (Residential and Small Business)...

    Broader source: Energy.gov (indexed) [DOE]

    NY-Sun CommercialIndustrial Incentive program that offers incentives for grid connected PV systems larger than 200 KW. The New York State Energy Research and Development...

  14. DOE Zero Energy Ready Home Case Study: AquaZephyr, Ithaca, NY...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AquaZephyr, Ithaca, NY DOE Zero Energy Ready Home Case Study: AquaZephyr, Ithaca, NY Case study of a DOE Zero Energy Ready home in Ithaca, NY, that achieves a HERS 56 without PV or ...

  15. DOE - Office of Legacy Management -- Crucible Steel Co of America - NY 34

    Office of Legacy Management (LM)

    Crucible Steel Co of America - NY 34 FUSRAP Considered Sites Site: Crucible Steel Co. of America (NY.34 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Syracuse , New York NY.34-1 Evaluation Year: 1987 NY.34-1 Site Operations: Research and Development; Small amount of Thorium forged and rolled; Large amounts of non-radioactive metals provided to the AEC. NY.34-1 Site Disposition: Eliminated - Potential for contamination remote NY.34-1

  16. DOE - Office of Legacy Management -- Enterprise Metal Products - NY 0-10

    Office of Legacy Management (LM)

    Enterprise Metal Products - NY 0-10 FUSRAP Considered Sites Site: Enterprise Metal Products (NY.0-10 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Brooklyn , New York NY.0-10-1 Evaluation Year: 1987 NY.0-10-1 Site Operations: Machined magnesium metal NY.0-10-1 Site Disposition: Eliminated - Potential for contamination remote NY.0-10-1 Radioactive Materials Handled: None Indicated Primary Radioactive Materials Handled: None Indicated

  17. DOE - Office of Legacy Management -- Fordham University - NY 0-12

    Office of Legacy Management (LM)

    Fordham University - NY 0-12 FUSRAP Considered Sites Site: Fordham University (NY.0-12 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: New York , New York NY.0-12-1 Evaluation Year: 1987 NY.0-12-1 Site Operations: Research and development involving small quantities of radioactive material in a controlled environment NY.0-12-1 Site Disposition: Eliminated - Potential for contamination remote NY.0-12-1 Radioactive Materials Handled: Yes

  18. DOE - Office of Legacy Management -- Linde Air Products Div - Buffalo - NY

    Office of Legacy Management (LM)

    65 Div - Buffalo - NY 65 FUSRAP Considered Sites Site: LINDE AIR PRODUCTS DIV. BUFFALO (NY.65 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: Linde Chandler Street Plant NY.65-1 Location: Buffalo , New York NY.65-1 Evaluation Year: 1987 NY.65-1 Site Operations: Developed and produced non-radioactive material for the Oak Ridge Gaseous Diffusion Plant under contract with the AEC. NY.65-2 Site Disposition: Eliminated - No indication that

  19. DOE - Office of Legacy Management -- Simmons Machine and Tool Inc - NY 35

    Office of Legacy Management (LM)

    Simmons Machine and Tool Inc - NY 35 FUSRAP Considered Sites Site: SIMMONS MACHINE AND TOOL, INC (NY.35) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: 1000 North Broadway , Albany , New York NY.35-1 Evaluation Year: 1987 NY.35-2 Site Operations: Tested equipment and machined uranium to test the equipment (one time event). NY.35-1 NY.35-2 Site Disposition: Eliminated - Potential for contamination considered remote due to limited scope

  20. DOE - Office of Legacy Management -- Eastman Kodak Laboratory - NY 0-09

    Office of Legacy Management (LM)

    Eastman Kodak Laboratory - NY 0-09 FUSRAP Considered Sites Site: Eastman Kodak Laboratory (NY.0-09 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: Eastman Kodak Rochester Lab NY.0-09-1 Location: Rochester , New York NY.0-09-1 Evaluation Year: 1987 NY.0-09-1 NY.0-09-2 Site Operations: Research and development with natural uranium solutions in 1943. NY.0-09-1 Site Disposition: Eliminated - Potential for contamination remote NY.0-09-2 Radioactive

  1. DOE - Office of Legacy Management -- Linde Air Products Division - NY 08

    Office of Legacy Management (LM)

    Division - NY 08 FUSRAP Considered Sites Linde Air Products Division - Towanda, NY Alternate Name(s): Praxair Linde Aire Products Div. of Union Carbide Corp. Linde Ceramics Plant Uranium Refinery, Linde Site NY.08-4 Location: East Park Drive and Woodward, Tonawanda, New York NY.08-5 Historical Operations: Processed uranium compounds for MED and AEC. Includes Towanda Landfill as a VP. NY.08-1 NY.08-2 Eligibility Determination: Eligible NY.08-9 Radiological Survey(s): Assessment Surveys NY.08-3

  2. DOE - Office of Legacy Management -- Radium Chemical Co Inc - NY 60

    Office of Legacy Management (LM)

    Radium Chemical Co Inc - NY 60 FUSRAP Considered Sites Site: RADIUM CHEMICAL CO., INC (NY.60 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: New York , New York NY.60-1 Evaluation Year: 1987 NY.60-1 Site Operations: Commercial Producer of Radium. NY.60-1 Site Disposition: Eliminated - Commercial site - EPA cleanup project NY.60-1 Radioactive Materials Handled: Yes NY.60-1 Primary Radioactive Materials Handled: Radium NY.60-1

  3. DOE - Office of Legacy Management -- Ferro Metal and Chemical Co - NY 42

    Office of Legacy Management (LM)

    Ferro Metal and Chemical Co - NY 42 FUSRAP Considered Sites Site: Ferro Metal & Chemical Co. (NY.42 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: 50 Broad Street , New York , New York NY.42-1 NY.42-2 Evaluation Year: 1987 NY.42-2 Site Operations: Procured uranium from foreign sources. No record of radioactive material at this site NY.42-1 NY.42-2 Site Disposition: Eliminated - No indication that radioactive materials were used at

  4. DOE - Office of Legacy Management -- Floyd Bennett Field - NY 0-11

    Office of Legacy Management (LM)

    Floyd Bennett Field - NY 0-11 FUSRAP Considered Sites Site: Floyd Bennett Field (NY.0-11 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: Naval Air Station NY.0-11-1 Location: Buildings 67 and 69 , Brooklyn , New York NY.0-11-1 Evaluation Year: 1987 NY.0-11-1 Site Operations: The Air station was considered by the AEC but was not used. NY.0-11-1 Site Disposition: Eliminated - No involvement with MED/AEC operations NY.0-11-1 Radioactive Materials

  5. DOE - Office of Legacy Management -- Union Mines Development Corp - NY 0-22

    Office of Legacy Management (LM)

    Mines Development Corp - NY 0-22 FUSRAP Considered Sites Site: UNION MINES DEVELOPMENT CORP. (NY.0-22) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: Union Carbide NY.0-22-1 Location: New York , New York NY.0-22-1 Evaluation Year: 1987 NY.0-22-1 Site Operations: The company owned uranium mines or reserves located in the western U.S. NY.0-22-1 Site Disposition: Eliminated - No reason to believe radioactive material was used at this site NY.0-22-1

  6. DOE - Office of Legacy Management -- Colonie - NY 06

    Office of Legacy Management (LM)

    of Engineers but will eventually transfer to the U.S. Department of Energy Office of Legacy Management. NY.06-1 - DOE Report (DOEOR20722-53); Colonie Interim Storage Site...

  7. NY-Sun Commerical/Industrial Incentive Program

    Broader source: Energy.gov [DOE]

    New York State Energy Research and Development Authority (NYSERDA) through NY-Sun Commercial/Industrial Incentive Program (PON 3082) provides incentives for installation of non-residential new grid...

  8. RenewableNY - An Industrial Energy Conservation Initiative

    SciTech Connect (OSTI)

    Lubarr, Tzipora

    2009-09-30

    The New York Industrial Retention Network (NYIRN) manages the RenewableNY program to assist industrial companies in New York City to implement energy efficiency projects. RenewableNY provides companies with project management assistance and grants to identify opportunities for energy savings and implement energy efficiency projects. The program helps companies identify energy efficient projects, complete an energy audit, and connect with energy contractors who install renewable energy and energy efficient equipment. It also provides grants to help cover the costs of installation for new systems and equipment. RenewableNY demonstrates that a small grant program that also provides project management assistance can incentivize companies to implement energy efficiency projects that might otherwise be avoided. Estimated savings through RenewableNY include 324,500 kWh saved through efficiency installations, 158 kW of solar energy systems installed, and 945 thm of gas avoided.

  9. DOE - Office of Legacy Management -- Ithaca Gun Co Inc - NY 53

    Office of Legacy Management (LM)

    Ithaca Gun Co Inc - NY 53 FUSRAP Considered Sites Site: ITHACA GUN CO., INC. (NY.53 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: 123 Lake Street , Ithaca , New York NY.53-1 Evaluation Year: 1994 NY.53-2 Site Operations: Conducted tests involving the forging of hollow uranium billets into tubes for the AEC. Also investigated alternative methods of producing fuel cores. NY.53-1 Site Disposition: Eliminated - No radioactive

  10. DOE - Office of Legacy Management -- Utica Street Warehouse - NY 0-23

    Office of Legacy Management (LM)

    Street Warehouse - NY 0-23 FUSRAP Considered Sites Site: UTICA STREET WAREHOUSE (NY.0-23) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: 240 West Utica Street , Buffalo , New York NY.0-23-2 Evaluation Year: 1987 NY.0-23-1 Site Operations: Stored and rebarrelled uranium process residues from operations at Linde. NY.0-23-3 Site Disposition: Eliminated - Original building demolished. Current land use - Parking facility. Potential for

  11. New York State Energy Research and Development Authority, Albany, NY |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy York State Energy Research and Development Authority, Albany, NY New York State Energy Research and Development Authority, Albany, NY This presentation on the NYSERDA Hydrogen Program was given on July 12, 2006. education_presentation_nyserda.pdf (2.64 MB) More Documents & Publications NYSERDA's RPS Customer Sited Tier Fuel Cell Program State of the States: Fuel Cells in America 2014 State of the States: Fuel Cells in America 2010

  12. Los Alamos technology to be featured on CSI: NY

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    LANL technology featured on CSI: NY Los Alamos technology to be featured on CSI: NY The multipurpose "sampler gun" rapidly collects and tracks radiological, chemical, and biological samples in solid, liquid, or gaseous forms. March 27, 2008 Los Alamos National Laboratory sits on top of a once-remote mesa in northern New Mexico with the Jemez mountains as a backdrop to research and innovation covering multi-disciplines from bioscience, sustainable energy sources, to plasma physics and

  13. DOE - Office of Legacy Management -- Pfohl Brothers Landfill - NY 66

    Office of Legacy Management (LM)

    Pfohl Brothers Landfill - NY 66 FUSRAP Considered Sites Site: Pfohl Brothers Landfill (NY.66 ) Designated Name: Alternate Name: Location: Evaluation Year: Site Operations: Site Disposition: Radioactive Materials Handled: Primary Radioactive Materials Handled: Radiological Survey(s): Site Status: Also see Five-Year Review Report Pfohl Brothers Landfill Superfund Site Erie County Town of Cheektowaga, New York EPA REGION 2 Congressional District(s): 30 Erie Cheektowaga NPL LISTING HISTORY Documents

  14. Origin State>> CA CA ID ID ID IL KY MD MO NM NM NY NY OH SC

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    MO NM NM NY NY OH SC TN TN TN, WA, CA TN TN TN TN Total Shipments by Route Lawrence Livermore National Laboratory General Atomics Batelle Energy Alliance Idaho National Laboratory Advanced Mixed Waste Treatment Project Argonne National Laboratory Paducah Gaseous Diffusion Plant Aberdeen Proving Grounds National Security Technologies Sandia National Laboratory Los Alamos National Laboratory Brookhaven National Laboratory CH2M Hill B&W West Valley, LLC Portsmouth Gaseous Diffusion Plant

  15. Origin State>> CA CA ID ID ID IL KY MD NM NM NV NY NY OH TN

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NM NM NV NY NY OH TN TN TN, WA, CA TN TN TN TN TX Total Shipments by Route Lawrence Livermore National Laboratory General Atomics Advanced Mixed Waste Treatment Project Batelle Energy Alliance Idaho National Laboratory Argonne National Laboratory Paducah Gaseous Diffusion Plant Aberdeen Proving Ground Los Alamos National Laboratory Sandia National Laboratory National Security Technologies Brookhaven National Laboratory West Valley Environmental Services Portsmouth Gaseous Diffusion Plant

  16. Origin State>> CA ID ID ID IL KY MD NM NM NY NY OH SC TN TN

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    MD NM NM NY NY OH SC TN TN TN, WA, CA TN TN TN TN TX Total Shipments by Route Lawrence Livermore National Laboratory Advanced Mixed Waste Treatment Project Batelle Energy Alliance Idaho National Laboratory Argonne National Laboratory Paducah Gaseous Diffusion Plant Aberdeen Proving Ground Los Alamos National Laboratory Sandia National Laboratory Brookhaven National Laboratory West Valley Environmental Services Portsmouth Gaseous Diffusion Plant Savannah River Site Duratek/Energy Solutions Babcox

  17. Origin State>> CA ID ID ID IL KY NV NY NY OH TN TN TN, WA, CA

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NV NY NY OH TN TN TN, WA, CA TN TN TN TN TX Total Shipments by Route Lawrence Livermore National Laboratory Advanced Mixed Waste Treatment Project Batelle Energy Alliance Idaho National Laboratory Argonne National Laboratory Paducah Gaseous Diffusion Plant National Security Technologies Brookhaven National Laboratory West Valley Environmental Services Portsmouth Gaseous Diffusion Plant Duratek/Energy Solutions Babcox & Wilcox Technical Services Y-12 Plant Materials & Energy Corporation

  18. Origin State>> CA ID ID ID IL MD NM NM NV NY NY OH SC TN TN

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NV NY NY OH SC TN TN TN, WA, CA TN TN TN Total Shipments by Route Lawrence Livermore National Laboratory Batelle Energy Alliance Idaho National Laboratory Advanced Mixed Waste Treatment Project Argonne National Laboratory Aberdeen Proving Ground Sandia National Laboratory Los Alamos National Laboratory National Security Technologies Brookhaven National Laboratory West Valley Environmental Services Portsmouth Gaseous Diffusion Plant Savannah River Site Duratek/Energy Solutions Babcox & Wilcox

  19. EV Community Readiness projects: New York City and Lower Hudson Valley Clean Communities, Inc. (NY, MA, PA); NYSERDA (ME, NH, VT, MA, RI, CT, NY, NJ, PA, DE, MD, DC)

    Broader source: Energy.gov [DOE]

    2013 DOE Hydrogen and Fuel Cells Program and Vehicle Technologies Program Annual Merit Review and Peer Evaluation Meeting

  20. DOE - Office of Legacy Management -- African Metals - NY 0-01

    Office of Legacy Management (LM)

    African Metals - NY 0-01 FUSRAP Considered Sites Site: African Metals (NY 0-01) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: Afrimet NY.0-01-1 Location: 41 Broad Street , New York , New York NY.0-01-2 Evaluation Year: 1987 NY.0-01-1 Site Operations: U.S. Agent for Union Miniere du Haut Katanga; site of the main corporate offices; no radioactive materials handled at this location. NY.0-01-1 Site Disposition: Eliminated - No potential for

  1. DOE - Office of Legacy Management -- Colorado Fuel and Iron - NY 0-08

    Office of Legacy Management (LM)

    Fuel and Iron - NY 0-08 FUSRAP Considered Sites Site: Colorado Fuel and Iron (NY.0-08 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Watervliet , New York NY.0-08-1 Evaluation Year: 1987 NY.0-08-1 Site Operations: Site was a contractor to DuPont. Exact nature of operations is not clear. No records to indicate that radioactive materials were handled at the site. NY.0-08-1 Site Disposition: Eliminated NY.0-08-1 Radioactive Materials

  2. DOE - Office of Legacy Management -- Frederick Flader Inc - NY 0-13

    Office of Legacy Management (LM)

    Frederick Flader Inc - NY 0-13 FUSRAP Considered Sites Site: Frederick Flader, Inc. (NY.0-13 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: Frederick Flader Division of Eaton Manufacturing Co. NY.0-13-1 Location: 583 Division Street , N. Tonawanda , New York NY.0-13-1 Evaluation Year: 1987 NY.0-13-1 Site Operations: Provided consulting services and supported development of auxiliary equipment related to nuclear power NY.0-13-1 Site Disposition:

  3. DOE - Office of Legacy Management -- Long Island College of Medicine - NY

    Office of Legacy Management (LM)

    0-14 Long Island College of Medicine - NY 0-14 FUSRAP Considered Sites Site: Long Island College of Medicine (NY.0-14 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: New York , New York NY.0-14-1 Evaluation Year: 1987 NY.0-14-1 Site Operations: Performed research utilizing small quantities of radioactive materials in a controlled environment. NY.0-14-1 Site Disposition: Eliminated - Potential for contamination remote NY.0-14-1

  4. DOE - Office of Legacy Management -- Lucius Pitkin - NY 0-15

    Office of Legacy Management (LM)

    Lucius Pitkin - NY 0-15 FUSRAP Considered Sites Site: Lucius Pitkin (NY.0-15 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: 47 Fulton Street , New York , New York NY.0-15-1 Evaluation Year: 1987 NY.0-15-1 Site Operations: No MED or AED work done at this site. Contractor supervised activities at Middlesex Sampling Plant in Middlesex, NJ such as assaying, sampling and weighing of ore. NY.0-15-1 NY.0-15-2 Site Disposition: Eliminated - No

  5. DOE - Office of Legacy Management -- Memorial Hospital - NY 0-16

    Office of Legacy Management (LM)

    Memorial Hospital - NY 0-16 FUSRAP Considered Sites Site: MEMORIAL HOSPITAL (NY.0-16 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: New York , New York NY.0-16-1 Evaluation Year: 1987 NY.0-16-1 Site Operations: Conducted studies for MED including a "Physiological Study of Sunbath Treatments." Involvement with radioactive materials unknown. NY.0-16-1 Site Disposition: Eliminated - Potential for contamination remote NY.0-16-1

  6. DOE - Office of Legacy Management -- Pyroferric Co - NY 0-20

    Office of Legacy Management (LM)

    Pyroferric Co - NY 0-20 FUSRAP Considered Sites Site: PYROFERRIC CO. (NY.0-20) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: 621 E. 216th Street , New York , New York NY.0-20-1 Evaluation Year: 1987 NY.0-20-1 Site Operations: One small scale experiment was conducted with non-radioactive material. NY.0-20-1 Site Disposition: Eliminated NY.0-20-1 Radioactive Materials Handled: No Primary Radioactive Materials Handled: None Radiological

  7. shaleusa5.pdf

    Gasoline and Diesel Fuel Update (EIA)

    ... NY PA NJ OH DC DE WV MD KY VA NC TN SC MI CANADA 2 0 0 1 0 0 Marcellus Shale Gas Play, Appalachian Basin Source: US Energy Information Administration based on data from WVGES , PA ...

  8. Champlain, NY Natural Gas Liquefied Natural Gas Imports (Million Cubic

    U.S. Energy Information Administration (EIA) Indexed Site

    Feet) (Million Cubic Feet) Champlain, NY Natural Gas Liquefied Natural Gas Imports (Million Cubic Feet) Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2014 63 2015 1 2 1 2 20 2016 56 76 20 20 3 4 - = No Data Reported; -- = Not Applicable; NA = Not Available; W = Withheld to avoid disclosure of individual company data. Release Date: 08/31/2016 Next Release Date: 09/30/2016 Referring Pages: U.S. Liquefied Natural Gas Imports by Point of Entry Champlain, NY LNG Imports from All Countr

  9. Submit Your Ideas for the NY Energy Data Jam | Department of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Submit Your Ideas for the NY Energy Data Jam Submit Your Ideas for the NY Energy Data Jam June 19, 2013 - 11:03am Q&A What idea would you present at the Data Jam? Join the...

  10. DOE - Office of Legacy Management -- Knolls Atomic Power Laboratory - NY 16

    Office of Legacy Management (LM)

    Knolls Atomic Power Laboratory - NY 16 Site ID (CSD Index Number): NY.16 Site Name: Knolls Atomic Power Laboratory Site Summary: Site Link: External Site Link: http://www.knollslab.com/ Alternate Name(s): Peek Street Facility Knolls Atomic Power Lab of General Electric, Schnectady Alternate Name Documents: Location: Niskayuna, NY and West Milton, NY Location Documents: Historical Operations (describe contaminants): The site was considered because it provided support to the Atomic Energy

  11. DOE - Office of Legacy Management -- Utica Drop Forge and Tool Corp - NY 39

    Office of Legacy Management (LM)

    Drop Forge and Tool Corp - NY 39 FUSRAP Considered Sites Site: UTICA DROP FORGE & TOOL CORP. (NY.39) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Utica , New York NY.39-1 Evaluation Year: 1994 NY.39-2 Site Operations: Interest expressed by Utica Drop Forge & Tool Corporation to Conduct Uranium Forging and Casting for the AEC. No indication that the contractor actually did a substantial amount of work of this nature at

  12. US MidAtl PA Site Consumption

    U.S. Energy Information Administration (EIA) Indexed Site

    MidAtl PA Site Consumption million Btu $0 $500 $1,000 $1,500 $2,000 $2,500 $3,000 US MidAtl PA Expenditures dollars ALL ENERGY average per household (excl. transportation) 0 2,000 4,000 6,000 8,000 10,000 12,000 US MidAtl PA Site Consumption kilowatthours $0 $250 $500 $750 $1,000 $1,250 $1,500 US MidAtl PA Expenditures dollars ELECTRICITY ONLY average per household * Pennsylvania households consume an average of 96 million Btu per year, 8% more than the U.S. average. Pennsylvania residents also

  13. Interoperability of Demand Response Resources Demonstration in NY

    SciTech Connect (OSTI)

    Wellington, Andre

    2014-03-31

    The Interoperability of Demand Response Resources Demonstration in NY (Interoperability Project) was awarded to Con Edison in 2009. The objective of the project was to develop and demonstrate methodologies to enhance the ability of customer sited Demand Response resources to integrate more effectively with electric delivery companies and regional transmission organizations.

  14. DOE - Office of Legacy Management -- Wolff-Alport and Co - NY 30

    Office of Legacy Management (LM)

    Wolff-Alport and Co - NY 30 FUSRAP Considered Sites Site: Wolff-Alport and Co (NY.30) Eliminated from consideration under FUSRAP - Referred to US EPA Region II and New York City Department of Health Designated Name: Not Designated Alternate Name: None Location: 1127 Irving Avenue , Brooklyn , New York NY.30-1 Evaluation Year: 1987 NY.30-1 Site Operations: Commercial operation -- sold thorium residues to the AEC, which in turn shipped the residues to Maywood for storage. NY.30-2 Site Disposition:

  15. Buffalo, NY Liquefied Natural Gas Exports (Million Cubic Feet)

    U.S. Energy Information Administration (EIA) Indexed Site

    (Million Cubic Feet) Buffalo, NY Liquefied Natural Gas Exports (Million Cubic Feet) Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2015 1 1 1 1 - = No Data Reported; -- = Not Applicable; NA = Not Available; W = Withheld to avoid disclosure of individual company data. Release Date: 08/31/2016 Next Release Date: 09/30/2016 Referring Pages: U.S.

  16. Palmetto Clean Energy (PaCE) Program

    Office of Energy Efficiency and Renewable Energy (EERE)

    PaCE funding comes from the customers of participating utilities who voluntarily choose to support the program through an additional charge on their monthly utility bills. Of the $4, $3.50 goes t...

  17. DOE - Office of Legacy Management -- Aeroprojects Inc - PA 22

    Office of Legacy Management (LM)

    Aeroprojects Inc - PA 22 FUSRAP Considered Sites Site: Aeroprojects, Inc. (PA.22 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: Sonabound Ultrasonics PA.22-1 Location: 200-T E. Rosedale Avenue , West Chester , Pennsylvania PA.22-3 Evaluation Year: Circa 1990 PA.22-1 PA.22-2 Site Operations: Research/Development including investigation of the use of ultrasonic energy. PA.22-1 Site Disposition: Eliminated - Conditions at site meet current

  18. DOE - Office of Legacy Management -- Sharples Corp - PA 29

    Office of Legacy Management (LM)

    Sharples Corp - PA 29 FUSRAP Considered Sites Site: SHARPLES CORP. (PA.29 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: 201 Spring Garden Street , Philadelphia , Pennsylvania & Philadelphia , Pennsylvania PA.29-2 PA.29-1 Evaluation Year: 1986 PA.29-1 Site Operations: Producer/broker of special chemicals - major MED supplier. PA.29-2 PA.29-3 Site Disposition: Eliminated - No indication that radioactive materials were used

  19. DOE Zero Energy Ready Home Case Study: Greenhill Contracting, New Paltz, NY

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    | Department of Energy New Paltz, NY DOE Zero Energy Ready Home Case Study: Greenhill Contracting, New Paltz, NY DOE Zero Energy Ready Home Case Study: Greenhill Contracting, New Paltz, NY Case study of a DOE Zero Energy Ready home in New Paltz, NY, that achieved a HERS score of 37 without PV or 7 with 7.5-kW PV. The two-story 2,288-ft2 home is one of 9 certified homes. All of the homes have R-22 ICF walls, R-20 closed-cell spray foam under the slab, a ground-source heat pump with

  20. I?raak Nuke, NXOO Leaa Km&l, NY00

    Office of Legacy Management (LM)

    W. ti. &&n,Nor I?raak Nuke, NXOO Leaa Km&l, NY00 fjlrt~olfloatlon Camad .- ,' I i 2 Jr,' ; !

  1. PaTu Wind Farm | Open Energy Information

    Open Energy Info (EERE)

    PaTu Wind Farm Jump to: navigation, search Name PaTu Wind Farm Facility PaTu Wind Farm Sector Wind energy Facility Type Commercial Scale Wind Facility Status In Service Developer...

  2. NUG Meeting November 9, 2004 (Pittsburgh, PA)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NUG Meeting November 9, 2004 (Pittsburgh, PA) Dates November 9, 2004 Location SuperComputing 2004 (SC2004) David L. Lawrence Convention Center Room 319/320 Pittsburgh, PA Agenda NERSC User Group (NUG) Meeting, Tuesday November 9th 2004 5:30 - 07:00 PM at SC2004 in Pittsburgh, Room 319/320 The NERSC User Group (NUG) is composed of all NERSC users to provide guidance in provision of center services and future development. NUG holds annual meetings, including BoFs at SC meetings, to discuss topics

  3. Champlain, NY Natural Gas Liquefied Natural Gas Imports from Canada

    U.S. Energy Information Administration (EIA) Indexed Site

    (Million Cubic Feet) Liquefied Natural Gas Imports from Canada (Million Cubic Feet) Champlain, NY Natural Gas Liquefied Natural Gas Imports from Canada (Million Cubic Feet) Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2014 63 2015 1 2 1 2 20 2016 56 76 20 20 3 4 - = No Data Reported; -- = Not Applicable; NA = Not Available; W = Withheld to avoid disclosure of individual company data. Release Date: 08/31/2016 Next Release Date: 09/30/2016 Referring Pages: U.S. Liquefied Natural Ga

  4. FIRST Robotics at NY Tech Valley | GE Global Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Pit Boss Reflects on Bot Challenge Click to email this to a friend (Opens in new window) Share on Facebook (Opens in new window) Click to share (Opens in new window) Click to share on LinkedIn (Opens in new window) Click to share on Tumblr (Opens in new window) Pit Boss Reflects on Bot Challenge Lynn DeRose 2015.03.27 Hi everyone, from BBQ to robots all in the same week! This past weekend I had the privilege to volunteer at the FIRST(tm) Robotics Competition (FRC) NY Tech Valley Regional at RPI.

  5. Microsoft PowerPoint - Xie_twpice_NY06.ppt

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Variational Analysis of Tropical Warm Pool International Cloud Experiment (TWP_ICE) Data (01/22/2006 - 2/13/2006) The TWP_ICE Workshop , NASA/GISS, New York, NY, 13-15 November, 2006 A joint effort between LLNL (Xie, McCoy, Klein), BMRC (Hume, Jakob), SUNYSB (Zhang), and other TWPICE participants 143km 130km 172km 99km 148km A Quick Update Done! 3-hourly radiosondes (6 stations) Background field from the ECMWF analysis Radar precipitation Surface turbulence fluxes from Monash University (Darwin

  6. DOE - Office of Legacy Management -- Philadelphia Navy Yard - PA 08

    Office of Legacy Management (LM)

    Philadelphia Navy Yard - PA 08 Site ID (CSD Index Number): PA.08 / PA.26 Site Name: PHILADELPHIA NAVY YARD Site Summary: This site was mistakenly assigned two numbers during FUSRAP's initial evaluation in the 1980s and 1990s. PA.26 was later removed from the site documents, and only PA.08 was used. Site Link: External Site Link: Alternate Name(s): Naval Boiler and Turbine Lab Alternate Name Documents: Location: Philadelphia , Pennsylvania Location Documents: PA.08-1 Historical Operations

  7. DOE - Office of Legacy Management -- Superior Steel Co - PA 03

    Office of Legacy Management (LM)

    Superior Steel Co - PA 03 FUSRAP Considered Sites Superior Steel, PA Alternate Name(s): Copper Weld, Inc. Superbolt Location: Carnegie, Pennsylvania PA.03-1 Historical Operations: Milled uranium metal for AEC. PA.03-4 Eligibility Determination: Eligible Radiological Survey(s): Assessment Survey PA.03-4 Site Status: Cleanup in progress by U.S. Army Corps of Engineers. USACE Website Long-term Care Requirements: To be determined upon completion. Also see Documents Related to Superior Steel, PA

  8. DOE - Office of Legacy Management -- Try Street Terminal - PA 14

    Office of Legacy Management (LM)

    Try Street Terminal - PA 14 FUSRAP Considered Sites Site: TRY STREET TERMINAL (PA.14 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Try Street Terminal , Pittsburgh , Pennsylvania PA.14-1 Evaluation Year: 1987 PA.14-1 Site Operations: Circa 1943 - facility used to store 20 plus drums of uranium slag. PA.14-1 Site Disposition: Eliminated - Potential for residual radioactive contamination considered remote PA.14-1 Radioactive

  9. Real-time sub-<mi>>ngstrom...

    Office of Scientific and Technical Information (OSTI)

    Real-time sub-<mi>>ngstrom imaging of reversible and irreversible conformations in rhodium catalysts and graphene Kisielowski, Christian; Wang,...

  10. DOE - Office of Legacy Management -- Heppanstall Co - PA 19

    Office of Legacy Management (LM)

    further consideration under FUSRAP Designated Name: Not Designated Alternate Name: Tippens Inc. PA.19-1 Location: 4620 Hatfield Street , Pittsburgh , Pennsylvania PA.19-4...

  11. PA Sangli Bundled Wind Project | Open Energy Information

    Open Energy Info (EERE)

    PA Sangli Bundled Wind Project Jump to: navigation, search Name: PA Sangli Bundled Wind Project Place: Maharashtra, India Zip: 416115 Sector: Wind energy Product:...

  12. DOE - Office of Legacy Management -- Carpenter Steel Co - PA...

    Office of Legacy Management (LM)

    Carpenter Steel Co - PA 12 FUSRAP Considered Sites Site: Carpenter Steel Co. (PA.12 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate ...

  13. DOE - Office of Legacy Management -- Jessop Steel Co - PA 17

    Office of Legacy Management (LM)

    Jessop Steel Co - PA 17 FUSRAP Considered Sites Site: JESSOP STEEL CO. (PA.17 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: ...

  14. DOE - Office of Legacy Management -- Beryllium Corp - PA 39

    Office of Legacy Management (LM)

    Beryllium Corp - PA 39 FUSRAP Considered Sites Site: BERYLLIUM CORP. (PA.39 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: Brush Beryllium PA.39-1 Location: Reading , Pennsylvania PA.39-1 Evaluation Year: 1987 PA.39-1 Site Operations: Production of Beryllium circa late 1940s - 50s. PA.39-1 Site Disposition: Eliminated - No radioactive material handled at this site, only Beryllium PA.39-1 Radioactive Materials Handled: No PA.39-1 Primary

  15. Technical Insights for Saltstone PA Maintenance

    SciTech Connect (OSTI)

    Flach, G.; Sarkar, S.; Mahadevan, S.; Kosson, D.

    2011-07-20

    The Cementitious Barriers Partnership (CBP) is a collaborative program sponsored by the US DOE Office of Waste Processing. The objective of the CBP is to develop a set of computational tools to improve understanding and prediction of the long-term structural, hydraulic, and chemical performance of cementitious barriers and waste forms used in nuclear applications. CBP tools are expected to better characterize and reduce the uncertainties of current methodologies for assessing cementitious barrier performance and increase the consistency and transparency of the assessment process, as the five-year program progresses. In September 2009, entering its second year of funded effort, the CBP sought opportunities to provide near-term tangible support to DOE Performance Assessments (PAs). The Savannah River Saltstone Disposal Facility (SDF) was selected for the initial PA support effort because (1) cementitious waste forms and barriers play a prominent role in the performance of the facility, (2) certain important long-term behaviors of cementitious materials composing the facility are uncertain, (3) review of the SDF PA by external stakeholders is ongoing, and (4) the DOE contractor responsible for the SDF PA is open to receiving technical assistance from the CBP. A review of the current (SRR Closure & Waste Disposal Authority 2009) and prior Saltstone PAs (e.g., Cook et al. 2005) suggested five potential opportunities for improving predictions. The candidate topics considered were (1) concrete degradation from external sulfate attack, (2) impact of atmospheric exposure to concrete and grout before closure, such as accelerated slag and Tc-99 oxidation, (3) mechanistic prediction of geochemical conditions, (4) concrete degradation from rebar corrosion due to carbonation, and (5) early age cracking from drying and/or thermal shrinkage. The candidate topics were down-selected considering the feasibility of addressing each issue within approximately six months, and

  16. Mi GmbH | Open Energy Information

    Open Energy Info (EERE)

    Mi GmbH Jump to: navigation, search Name: Mi GmbH Place: Switzerland Zip: CH-6340 Sector: Solar Product: Baar-based manufacturer and distributor of fruit juices. The firm is also...

  17. DOE - Office of Legacy Management -- Koppers Co Inc - PA 25

    Office of Legacy Management (LM)

    Koppers Co Inc - PA 25 FUSRAP Considered Sites Site: KOPPERS CO., INC. (PA.25 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Pittsburgh , Pennsylvania PA.25-1 Evaluation Year: 1987 PA.25-2 Site Operations: Conducted pilot-scale studies on the commercial production of UF4 and UF6. PA.25-1 Site Disposition: Eliminated - No Authority - Facility was licensed to handle nuclear materials PA.25-2 PA.25-3 Radioactive Materials Handled:

  18. DOE - Office of Legacy Management -- Catalytic Co - PA 40

    Office of Legacy Management (LM)

    Catalytic Co - PA 40 FUSRAP Considered Sites Site: Catalytic Co. (PA.40 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Philadelphia , Pennsylvania PA.40-1 Evaluation Year: 1991 PA.40-1 Site Operations: Prime contractor for construction of the Fernald facility. Records indicate one time shipment of a very small quantity (4 lbs) of uranium metal to this site. PA.40-1 Site Disposition: Eliminated - Construction contractor -

  19. DOE - Office of Legacy Management -- Foote Mineral Co - PA 27

    Office of Legacy Management (LM)

    Foote Mineral Co - PA 27 FUSRAP Considered Sites Site: Foote Mineral Co. (PA.27 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Exton , Pennsylvania PA.27-1 Evaluation Year: 1987 PA.27-1 Site Operations: Processed rare earth, principally zirconium and monazite sand was processed on a pilot-plant scale. PA.27-2 Site Disposition: Eliminated - Limited quantity of material handled - Potential for contamination considered remote

  20. DOE - Office of Legacy Management -- Heppenstall Co - PA 19

    Office of Legacy Management (LM)

    Heppenstall Co - PA 19 Site ID (CSD Index Number): PA.19 Site Name: Heppenstall Co. Site Summary: Site Link: External Site Link: Alternate Name(s): Tippens Inc. Alternate Name Documents: PA.19-1 Location: 4620 Hatfield Street , Pittsburgh , Pennsylvania Location Documents: PA.19-4 Historical Operations (describe contaminants): Forged approximately 100,000 pounds of uranium during a six month period in 1955. Historical Operations Documents: PA.19-1 Eligibility Determination: Eliminated -

  1. DOE - Office of Legacy Management -- Shippingport Atomic Power Plant - PA

    Office of Legacy Management (LM)

    13 Shippingport Atomic Power Plant - PA 13 FUSRAP Considered Sites Site: SHIPPINGPORT ATOMIC POWER PLANT (PA.13 ) Eliminated from further consideration under FUSRAP. Designated Name: Not Designated Alternate Name: Duquesne Light Company PA.13-1 Location: 25 miles west of Pittsburgh in Beaver County , Shippingport , Pennsylvania PA.13-2 Evaluation Year: circa 1987 PA.13-3 Site Operations: First commercially operated nuclear power reactor. Joint project (Federal Government an Duquesne Light

  2. DOE - Office of Legacy Management -- Summerville Tube Co - PA 24

    Office of Legacy Management (LM)

    Summerville Tube Co - PA 24 FUSRAP Considered Sites Site: SUMMERVILLE TUBE CO. (PA.24) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Bridgeport , Pennsylvania PA.24-1 Evaluation Year: 1987 PA.24-1 Site Operations: Metal fabrication research and development on uranium metal in the early 1940s - Cold drawing of tuballoy aluminum sheathing. PA.24-1 Site Disposition: Eliminated - Potential for residual radioactive contamination

  3. miRNAs in brain development

    SciTech Connect (OSTI)

    Petri, Rebecca; Malmevik, Josephine; Fasching, Liana; Åkerblom, Malin; Jakobsson, Johan

    2014-02-01

    MicroRNAs (miRNAs) are small, non-coding RNAs that negatively regulate gene expression at the post-transcriptional level. In the brain, a large number of miRNAs are expressed and there is a growing body of evidence demonstrating that miRNAs are essential for brain development and neuronal function. Conditional knockout studies of the core components in the miRNA biogenesis pathway, such as Dicer and DGCR8, have demonstrated a crucial role for miRNAs during the development of the central nervous system. Furthermore, mice deleted for specific miRNAs and miRNA-clusters demonstrate diverse functional roles for different miRNAs during the development of different brain structures. miRNAs have been proposed to regulate cellular functions such as differentiation, proliferation and fate-determination of neural progenitors. In this review we summarise the findings from recent studies that highlight the importance of miRNAs in brain development with a focus on the mouse model. We also discuss the technical limitations of current miRNA studies that still limit our understanding of this family of non-coding RNAs and propose the use of novel and refined technologies that are needed in order to fully determine the impact of specific miRNAs in brain development. - Highlights: • miRNAs are essential for brain development and neuronal function. • KO of Dicer is embryonically lethal. • Conditional Dicer KO results in defective proliferation or increased apoptosis. • KO of individual miRNAs or miRNA families is necessary to determine function.

  4. DOE-RL FOIA/PA Office

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    2/03 FRI 10:02 FAX 1 509 376 9704 DOE-RL FOIA/PA Office [41002 .,UU".. ...,. '.1..1 Department of Energy .Rlchland Operations Office P.O. Box 550 Richland, Washington 993.52 APR. 4 2fJOa ( 03~PRO.O389 Mr. D. B. Van Leuven, President and Chief Executive Officer Fluor Hanford, Inc. Richland, Washington 993~2 DearMr; Van Leuven: CONTRACT NO. DB-ACO6-96RL13200 -REDUCTION IN LONG-TERM LIABll..ITIES The U.S. Department of Energy (DOE), Richland Operations Office (RL). is C1UTCntly reviewing the

  5. DOE - Office of Legacy Management -- Michigan Velsicol Chemical Corp - MI

    Office of Legacy Management (LM)

    03 Michigan Velsicol Chemical Corp - MI 03 FUSRAP Considered Sites Site: MICHIGAN [VELSICOL] CHEMICAL CORP. (MI.03 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: Velsicol Chemical Corp. MI.03-1 Location: St. Louis , Michigan MI.03-2 Evaluation Year: Circa 1987 MI.03-3 Site Operations: Rare earth processing facility. MI.03-2 Site Disposition: Eliminated - No Authority - NRC survey MI.03-3 Radioactive Materials Handled: Yes Primary Radioactive

  6. DOE - Office of Legacy Management -- Star Cutter Corp - MI 15

    Office of Legacy Management (LM)

    Star Cutter Corp - MI 15 FUSRAP Considered Sites Site: STAR CUTTER CORP. (MI.15) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Farmington , Michigan MI.15-1 Evaluation Year: 1991 MI.15-2 Site Operations: Performed a one time uranium slug drilling operation test in 1956. MI.15-3 MI.15-1 Site Disposition: Eliminated - Potential for contamination considered remote based on limited scope and quantity of materials handled MI.15-2 Radioactive

  7. PaSol Italia SpA | Open Energy Information

    Open Energy Info (EERE)

    Name: PaSol Italia SpA Place: Varallo Pombia, Italy Zip: 28040 Sector: Solar Product: PA.SOL was formed by local private investors in order to initiate local PV module...

  8. Meeting Summary for HTF PA Scoping | Department of Energy

    Office of Environmental Management (EM)

    for HTF PA Scoping Meeting Summary for HTF PA Scoping Meeting Notes for the Savannah River Site H-Area Tank Farm Performance Assessment Scoping Meeting PDF icon Savannah River Site...

  9. DOE - Office of Legacy Management -- Frankford Arsenal - PA 21

    Office of Legacy Management (LM)

    DOD PA.21-2 Also see Documents Related to Frankford Arsenal PA.21-1 - AEC Memorandum; Smith to Hughes; Subject: Shipment of Uranium Metal to Frankfort Arsenal; June 23, 1952 ...

  10. File:USDA-CE-Production-GIFmaps-NY.pdf | Open Energy Information

    Open Energy Info (EERE)

    NY.pdf Jump to: navigation, search File File history File usage New York Ethanol Plant Locations Size of this preview: 776 600 pixels. Full resolution (1,650 1,275 pixels,...

  11. DOE - Office of Legacy Management -- Bettis Atomic Power Laboratories - PA

    Office of Legacy Management (LM)

    44 Bettis Atomic Power Laboratories - PA 44 FUSRAP Considered Sites Site: Bettis Atomic Power Laboratories (PA.44 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Allegheny County , West Mifflin , Pennsylvania PA.44-1 Evaluation Year: Circa 1987 PA.44-2 Site Operations: Conducted activities directed toward the design, development, testing, and operational follow of nuclear reactor propulsion plants for Naval surface and

  12. BuildSmart NY Innovators Summit Offers Sneak Peek at Better Buildings

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Challenge Solutions to Come | Department of Energy BuildSmart NY Innovators Summit Offers Sneak Peek at Better Buildings Challenge Solutions to Come BuildSmart NY Innovators Summit Offers Sneak Peek at Better Buildings Challenge Solutions to Come September 18, 2014 - 12:32pm Addthis The graphic above highlights New York Power Authority’s energy efficiency goals. | Courtesy of New York Power Authority The graphic above highlights New York Power Authority's energy efficiency goals. |

  13. DOE - Office of Legacy Management -- Pfaltz and Bauer Inc - New York - NY

    Office of Legacy Management (LM)

    45 New York - NY 45 FUSRAP Considered Sites Site: Pfaltz and Bauer Inc - New York (NY.45) Designated Name: Alternate Name: Location: Evaluation Year: Site Operations: Site Disposition: Radioactive Materials Handled: Primary Radioactive Materials Handled: Radiological Survey(s): Site Status: This site is one of a group of 77 FUSRAP considered sites for which few, if any records are available in their respective site files to provide an historical account of past operations and their

  14. DOE - Office of Legacy Management -- Pier 38 - NY 0-18

    Office of Legacy Management (LM)

    Pier 38 - NY 0-18 FUSRAP Considered Sites Site: Pier 38 (NY.0-18 ) Designated Name: Alternate Name: Location: Evaluation Year: Site Operations: Site Disposition: Radioactive Materials Handled: Primary Radioactive Materials Handled: Radiological Survey(s): Site Status: This site is one of a group of 77 FUSRAP considered sites for which few, if any records are available in their respective site files to provide an historical account of past operations and their relationship, if any, with MED/AEC

  15. DOE - Office of Legacy Management -- West Milton Reactor Site - NY 21

    Office of Legacy Management (LM)

    Milton Reactor Site - NY 21 FUSRAP Considered Sites Site: West Milton Reactor Site (NY.21) Designated Name: Alternate Name: Location: Evaluation Year: Site Operations: Site Disposition: Radioactive Materials Handled: Primary Radioactive Materials Handled: Radiological Survey(s): Site Status: This site is one of a group of 77 FUSRAP considered sites for which few, if any records are available in their respective site files to provide an historical account of past operations and their

  16. U.S. Natural Gas Exports to Mexico

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    MI St. Clair, MI Noyes, MN Warroad, MN Babb, MT Havre, MT Port of Morgan, MT Sherwood, ND Pittsburg, NH Buffalo, NY Grand Island, NY Massena, NY Niagara Falls, NY Waddington, NY...

  17. DOE - Office of Legacy Management -- Wolverine Tube Division - MI 05

    Office of Legacy Management (LM)

    Wolverine Tube Division - MI 05 FUSRAP Considered Sites Site: Wolverine Tube Division (MI.05) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: Wolverine Tube Division of Calumet & Hecla Consolidated Copper Co. Star Tool Hermes Automotive Manufacturing Corporation MI.05-1 MI.05-2 Location: 1411 Central Avenue , Detroit , Michigan MI.05-3 Evaluation Year: 1990 MI.05-2 Site Operations: 1943 - Conducted research and development of methods for spinning

  18. DOE - Office of Legacy Management -- Adrian - MI 01

    Office of Legacy Management (LM)

    Adrian - MI 01 FUSRAP Considered Sites Adrian, MI Alternate Name(s): Bridgeport Brass Co. Special Metals Extrusion Plant Bridgeport Brass Company General Motors General Motors Company, Adrian MI.01-1 Location: 1450 East Beecher Street, Adrian, Michigan MI.01-3 Historical Operations: Performed uranium extrusion research and development and metal fabrication work for the AEC using uranium, thorium, and plutonium. MI.01-2 Eligibility Determination: Eligible MI.01-1 Radiological Survey(s):

  19. DOE - Office of Legacy Management -- Carboloy Co - MI 12

    Office of Legacy Management (LM)

    Carboloy Co - MI 12 FUSRAP Considered Sites Site: Carboloy Co. (MI.12 ) Eliminated from further consideration under FUSRAP - AEC licensed facility Designated Name: Not Designated Alternate Name: General Electric MI.12-1 Location: 11177 E. Eight Mile Road , Detroit , Michigan MI.12-1 MI.12-2 Evaluation Year: 1987-1991 MI.12-3 MI.12-4 MI.12-6 Site Operations: Turned-down the outer diameter of uranium metal slugs and conducted pilot plant scale operations for hot pressing uranium dioxide pellets

  20. Demonstration Assessment of LED Roadway Lighting: Philadelphia, PA

    Office of Scientific and Technical Information (OSTI)

    (Technical Report) | SciTech Connect Demonstration Assessment of LED Roadway Lighting: Philadelphia, PA Citation Details In-Document Search Title: Demonstration Assessment of LED Roadway Lighting: Philadelphia, PA For this demonstration assessment, 10 different groups of LED luminaires were installed at three sites in Philadelphia, PA. Each of the three sites represented a different set of conditions, most importantly with regard to the incumbent HPS luminaires, which were nominally 100 W,

  1. Buffalo, NY Liquefied Natural Gas Exports to Canada (Million Cubic Feet)

    U.S. Energy Information Administration (EIA) Indexed Site

    to Canada (Million Cubic Feet) Buffalo, NY Liquefied Natural Gas Exports to Canada (Million Cubic Feet) Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2015 1 1 1 1 - = No Data Reported; -- = Not Applicable; NA = Not Available; W = Withheld to avoid disclosure of individual company data. Release Date: 08/31/2016 Next Release Date: 09/30/2016 Referring Pages: U.S. Liquefied Natural Gas Exports by Point of Exit Buffalo, NY Liquefied Natural Gas Exports to Canada

  2. Champlain, NY Natural Gas Pipeline Imports From Canada (Million Cubic Feet)

    Gasoline and Diesel Fuel Update (EIA)

    Feet) (Million Cubic Feet) Champlain, NY Natural Gas Liquefied Natural Gas Imports (Million Cubic Feet) Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2014 63 2015 1 2 1 2 20 2016 56 76 20 20 3 4 - = No Data Reported; -- = Not Applicable; NA = Not Available; W = Withheld to avoid disclosure of individual company data. Release Date: 08/31/2016 Next Release Date: 09/30/2016 Referring Pages: U.S. Liquefied Natural Gas Imports by Point of Entry Champlain, NY LNG Imports from All Countries

  3. DOE - Office of Legacy Management -- Canonsburg Industrial Park - PA 05

    Office of Legacy Management (LM)

    Canonsburg Industrial Park - PA 05 Site ID (CSD Index Number): PA.05 Site Name: Canonsburg Industrial Park Site Summary: Site Link: Canonsburg, Pennsylvania, Disposal Site External Site Link: Alternate Name(s): Alternate Name Documents: Location: Location Documents: Historical Operations (describe contaminants): Historical Operations Documents: Eligibility Determination: Eligibility Determination Documents: Radiological Surveys Conducted (List of different Rad Surveys): Radiological Surveys

  4. DOE - Office of Legacy Management -- Oliver Corp - MI 11

    Office of Legacy Management (LM)

    Oliver Corp - MI 11 FUSRAP Considered Sites Site: OLIVER CORP. (MI.11 ) Eliminated from further consideration under FUSRAP - Referred to NRC Designated Name: Not Designated Alternate Name: Behnke Warehousing Incorporated MI.11-1 Location: 433 East Michigan Avenue , Battle Creek , Michigan MI.11-1 Evaluation Year: 1986 MI.11-4 Site Operations: Conducted production scale briquetting of green salt and magnesium blend under AEC license Nos. SNM-591, SUB-579, and C-3725. MI.11-1 MI.11-3 Site

  5. The NuMI Neutrino Beam

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Adamson, P.; Anderson, K.; Andrews, M.; Andrews, R.; Anghel, I.; Augustine, D.; Aurisano, A.; Avvakumov, S.; Ayres, D. S.; Baller, B.; et al

    2015-10-20

    Our paper describes the hardware and operations of the Neutrinos at the Main Injector (NuMI) beam at Fermilab. It elaborates on the design considerations for the beam as a whole and for individual elements. The most important part of our design details pertaining to individual components is described. Beam monitoring systems and procedures, including the tuning and alignment of the beam and NuMI long-term performance, are also discussed.

  6. DOE - Office of Legacy Management -- Detrex Corp - MI 10

    Office of Legacy Management (LM)

    Detrex Corp - MI 10 FUSRAP Considered Sites Site: Detrex Corp. (MI.10 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Detroit , Michigan MI.10-1 Evaluation Year: 1987 MI.10-2 Site Operations: Conducted experimental runs relative to pickling/degreasing of one handful of uranium turnings MI.10-1 Site Disposition: Eliminated - Potential for contamination considered remote due to small quantity of material handled - There is no

  7. DOE Zero Energy Ready Home Case Study: Greenhill Contracting, New Paltz, NY

    Broader source: Energy.gov [DOE]

    Case study of a DOE Zero Energy Ready home in New Paltz, NY, that achieved a HERS score of 37 without PV or 7 with 7.5-kW PV. The two-story 2,288-ft2 home is one of 9 certified homes. All of the...

  8. DOE Zero Energy Ready Home Case Study: AquaZephyr, Ithaca, NY

    Broader source: Energy.gov [DOE]

    Case study of a DOE Zero Energy Ready home in Ithaca, NY, that achieves a HERS 56 without PV or HERS 15 with 4-kW of PV. The two-story, 1,664-ft2 home is one of 17 single-family and 4 duplex homes...

  9. DOE Zero Energy Ready Home Case Study: AquaZephyr, Ithaca, NY...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Case study of a DOE Zero Energy Ready home in Ithaca, NY, that achieves a HERS 56 without PV or HERS 15 with 4-kW of PV. The two-story, 1,664-ft2 home is one of 17 single-family ...

  10. SGDP Report: Interoperability of Demand Response Resources Demonstration in NY (February 2015)

    Office of Energy Efficiency and Renewable Energy (EERE)

    The Interoperability of Demand Response Resources Demonstration in NY was awarded to Con Edison in 2009 as part of DOE's Smart Grid Demonstration Project (SGDP) grants funded by the Recovery Act. The objective of the project was to develop and demonstrate methodologies to enhance the ability of customer sited demand response resources, both conventional and renewable, to integrate more effectively with electric delivery companies.

  11. SGDP Report Now Available: Interoperability of Demand Response Resources Demonstration in NY (February 2015)

    Broader source: Energy.gov [DOE]

    The Interoperability of Demand Response Resources Demonstration in NY was awarded to Con Edison in 2009 as part of DOE's Smart Grid Demonstration Project (SGDP) grants funded by the Recovery Act. The objective of the project was to develop and demonstrate methodologies to enhance the ability of customer sited demand response resources, both conventional and renewable, to integrate more effectively with electric delivery companies

  12. Palmco Power PA, LLC (Pennsylvania) | Open Energy Information

    Open Energy Info (EERE)

    Pennsylvania) Jump to: navigation, search Name: Palmco Power PA, LLC Place: Pennsylvania Phone Number: (877) 726-5862 Website: www.palmcoenergy.com Outage Hotline: (877) 726-5862...

  13. DOE - Office of Legacy Management -- Aliquippa - PA 07

    Office of Legacy Management (LM)

    This site is managed by the U.S. Department of Energy Office of Legacy Management. PA.07-1 - DOE Memorandum; Coffman to LaGrone; Designation of Universal Cyclops, Inc., Titusville ...

  14. Hanford Site Waste Management Area C Performance Assessment (PA) Current

    Office of Environmental Management (EM)

    Status | Department of Energy Assessment (PA) Current Status Hanford Site Waste Management Area C Performance Assessment (PA) Current Status Marcel Bergeron Washignton River Protection Solutions Alaa Aly INTERA Performance and Risk Assessment Community of Practice Technical Exchange December 11-12, 2014 To view all the P&RA CoP 2014 Technical Exchange Meeting videos click here. Video Presentation - Part 1 Video Presentation - Part 2 Hanford Site Waste Management Area C Performance

  15. DOE - Office of Legacy Management -- Pennsylvania Disposal Site - PA 43

    Office of Legacy Management (LM)

    Disposal Site - PA 43 FUSRAP Considered Sites Site: Pennsylvania Disposal Site (PA.43) Designated Name: Alternate Name: Location: Evaluation Year: Site Operations: Site Disposition: Radioactive Materials Handled: Primary Radioactive Materials Handled: Radiological Survey(s): Site Status: This site is one of a group of 77 FUSRAP considered sites for which few, if any records are available in their respective site files to provide an historical account of past operations and their relationship, if

  16. DOE - Office of Legacy Management -- Pennsylvania Ordnance Works - PA 32

    Office of Legacy Management (LM)

    Ordnance Works - PA 32 FUSRAP Considered Sites Site: Pennsylvania Ordnance Works (PA.32 ) Designated Name: Alternate Name: Location: Evaluation Year: Site Operations: Site Disposition: Radioactive Materials Handled: Primary Radioactive Materials Handled: Radiological Survey(s): Site Status: This site is one of a group of 77 FUSRAP considered sites for which few, if any records are available in their respective site files to provide an historical account of past operations and their relationship,

  17. DOE - Office of Legacy Management -- U S Bureau of Mines - PA 36

    Office of Legacy Management (LM)

    PA 36 FUSRAP Considered Sites Site: U. S. BUREAU OF MINES (PA.36) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Bruceton , Pennsylvania PA.36-1 Evaluation Year: 1987 PA.36-2 Site Operations: Conducted studied on explosiveness of Uranium, Thorium and Beryllium. PA.36-1 PA.36-3 Site Disposition: Eliminated - Small amounts of radioactive materials used - Potential for residual radioactive contamination considered remote PA.36-2

  18. DOE - Office of Legacy Management -- Shallow Land Disposal Area - PA 45

    Office of Legacy Management (LM)

    Shallow Land Disposal Area - PA 45 FUSRAP Considered Sites Shallow Land Disposal Area, PA Alternate Name(s): Parks Township Shallow Land Disposal Area Nuclear Materials and Equipment Corporation (NUMEC) Babcock and Wilcox Parks Facilities PA.45-1 PA.45-5 PA.45-6 Location: PA Route 66 and Kissimere Road, Parks Township, Apollo, Pennsylvania PA.45-1 Historical Operations: Fabricated nuclear fuel under an NRC license as an extension of NUMEC Apollo production facilities. PA.45-1 PA.45-5 Eligibility

  19. DOE - Office of Legacy Management -- Naval Ordnance Plant - MI...

    Office of Legacy Management (LM)

    Eliminated from further consideration under FUSRAP - Referred to DoD for action Designated ... MI.0-03-1 Site Disposition: Eliminated - No Authority - Referred to DoD MI.0-03-1 ...

  20. Morphological studies on block copolymer modified PA 6 blends

    SciTech Connect (OSTI)

    Poindl, M. E-mail: christian.bonten@ikt.uni-stuttgart.de; Bonten, C. E-mail: christian.bonten@ikt.uni-stuttgart.de

    2014-05-15

    Recent studies show that compounding polyamide 6 (PA 6) with a PA 6 polyether block copolymers made by reaction injection molding (RIM) or continuous anionic polymerization in a reactive extrusion process (REX) result in blends with high impact strength and high stiffness compared to conventional rubber blends. In this paper, different high impact PA 6 blends were prepared using a twin screw extruder. The different impact modifiers were an ethylene propylene copolymer, a PA PA 6 polyether block copolymer made by reaction injection molding and one made by reactive extrusion. To ensure good particle matrix bonding, the ethylene propylene copolymer was grafted with maleic anhydride (EPR-g-MA). Due to the molecular structure of the two block copolymers, a coupling agent was not necessary. The block copolymers are semi-crystalline and partially cross-linked in contrast to commonly used amorphous rubbers which are usually uncured. The combination of different analysis methods like atomic force microscopy (AFM), transmission electron microscopy (TEM) and scanning electron microscopy (SEM) gave a detailed view in the structure of the blends. Due to the partial cross-linking, the particles of the block copolymers in the blends are not spherical like the ones of ethylene propylene copolymer. The differences in molecular structure, miscibility and grafting of the impact modifiers result in different mechanical properties and different blend morphologies.

  1. DOE Zero Energy Ready Home Case Study: Ferguson Design and Construction Inc., Sagaponack, NY, Custom Home

    Broader source: Energy.gov [DOE]

    Case study of a DOE Zero Energy Ready Home in Long Island, NY, that scored HERS 43 without PV. This 5,088-square-foot custom home has R-25 double-stud walls, a vaulted roof with R-40 blown cellulose, R-10 XPS under slab, a hydro air system with 91% efficient boiler for forced air and radiant floor heat, and 100% LED lights.

  2. DOE Zero Energy Ready Home Case Study 2013: Ferguson Design and Construction, Inc., Sagaponak, NY

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Ferguson Design & Construction, Inc. Sagaponack, NY BUILDING TECHNOLOGIES OFFICE The U.S. Department of Energy invites home builders across the country to meet the extraordinary levels of excellence and quality specifi ed in DOE's Zero Energy Ready Home program (formerly known as Challenge Home). Every DOE Zero Energy ReadyHome starts with ENERGY STAR for Homes Version 3 for an energy-effi cient home built on a solid foundation of building science research. Advanced technologies are designed

  3. DOE Zero Energy Ready Home Case Study 2013: Ithaca Neighborhood Housing Services, Ithaca, NY

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Ithaca Neighborhood Housing Services Ithaca, NY BUILDING TECHNOLOGIES OFFICE The U.S. Department of Energy invites home builders across the country to meet the extraordinary levels of excellence and quality specifi ed in DOE's Zero Energy Ready Home program (formerly known as Challenge Home). Every DOE Zero Energy Ready Home starts with ENERGY STAR for Homes Version 3 for an energy-effi cient home built on a solid foundation of building science research. Advanced technologies are designed in to

  4. miR-132 and miR-212 are increased in pancreatic cancer and target the retinoblastoma tumor suppressor

    SciTech Connect (OSTI)

    Park, Jong-Kook; Henry, Jon C.; Jiang, Jinmai; Esau, Christine; Gusev, Yuriy; Lerner, Megan R.; Postier, Russell G.; Brackett, Daniel J.; Schmittgen, Thomas D.

    2011-03-25

    Research highlights: {yields} The expression of miR-132 and miR-212 are significantly increased in pancreatic cancer. {yields} miR-132 and miR-212 target the tumor suppressor pRb, resulting in enhanced proliferation. {yields} miR-132 and miR-212 expression is increased by a {beta}2 adrenergic receptor agonist, suggesting a novel mechanism for pancreatic cancer progression. -- Abstract: Numerous microRNAs (miRNAs) are reported as differentially expressed in cancer, however the consequence of miRNA deregulation in cancer is unknown for many miRNAs. We report that two miRNAs located on chromosome 17p13, miR-132 and miR-212, are over-expressed in pancreatic adenocarcinoma (PDAC) tissues. Both miRNAs are predicted to target the retinoblastoma tumor suppressor, Rb1. Validation of this interaction was confirmed by luciferase reporter assay and western blot in a pancreatic cancer cell line transfected with pre-miR-212 and pre-miR-132 oligos. Cell proliferation was enhanced in Panc-1 cells transfected with pre-miR-132/-212 oligos. Conversely, antisense oligos to miR-132/-212 reduced cell proliferation and caused a G{sub 2}/M cell cycle arrest. The mRNA of a number of E2F transcriptional targets were increased in cells over expressing miR-132/-212. Exposing Panc-1 cells to the {beta}2 adrenergic receptor agonist, terbutaline, increased the miR-132 and miR-212 expression by 2- to 4-fold. We report that over-expression of miR-132 and miR-212 result in reduced pRb protein in pancreatic cancer cells and that the increase in cell proliferation from over-expression of these miRNAs is likely due to increased expression of several E2F target genes. The {beta}2 adrenergic pathway may play an important role in this novel mechanism.

  5. “Nodal Gap” induced by the incommensurate diagonal spin density modulation in underdoped high- <mi>Tmi>c> superconductors

    SciTech Connect (OSTI)

    Zhou, Tao; Gao, Yi; Zhu, Jian -Xin

    2015-03-07

    Recently it was revealed that the whole Fermi surface is fully gapped for several families of underdoped cuprates. The existence of the finite energy gap along the <mi>d>-wave nodal lines (nodal gap) contrasts the common understanding of the <mi>d>-wave pairing symmetry, which challenges the present theories for the high-<mi>Tmi><mi>c>superconductors. Here we propose that the incommensurate diagonal spin-density-wave order can account for the above experimental observation. The Fermi surface and the local density of states are also studied. Our results are in good agreement with many important experiments in high-<mi>Tmi><mi>c>superconductors.

  6. Appendix SCR: Feature, Event, and Process Screening for PA

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    SCR-2014 Feature, Event, and Process Screening for PA United States Department of Energy Waste Isolation Pilot Plant Carlsbad Field Office Carlsbad, New Mexico Compliance Recertification Application 2014 Appendix SCR-2014 Feature, Event, and Process Screening for PA Table of Contents SCR-1.0 Introduction SCR-2.0 Basis for FEPs Screening Process SCR-2.1 Requirement for FEPs SCR-2.2 FEPs List Development for the CCA SCR-2.3 Criteria for Screening of FEPs and Categorization of Retained FEPs

  7. DOE - Office of Legacy Management -- Babcock and Wilcox Co - PA 18

    Office of Legacy Management (LM)

    Babcock and Wilcox Co - PA 18 FUSRAP Considered Sites Site: Babcock and Wilcox Co (PA 18) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: Tubular Products Division PA.18-1 Location: Beaver Falls , Pennsylvania PA.18-1 Evaluation Year: 1990 PA.18-1 Site Operations: Performed development work to pierce uranium billets for extrusion to tubes. No indication that the piercing operation was conducted. PA.18-1 Site Disposition: Eliminated - No

  8. DOE - Office of Legacy Management -- Bartol Research Foundation - PA 0-02

    Office of Legacy Management (LM)

    Bartol Research Foundation - PA 0-02 FUSRAP Considered Sites Site: Bartol Research Foundation (PA 0-02) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: The Franklin Institute PA.0-02-1 Location: Swathmore , Pennsylvania PA.0-02-1 Evaluation Year: 1987 PA.0-02-1 Site Operations: Research organization. Possibly performed radiation monitoring and possibly supplied monitoring equipment to Monsanto Chemical Company. PA.0-02-1 Site Disposition:

  9. DOE - Office of Legacy Management -- Curtiss-Wright Corp - PA 37

    Office of Legacy Management (LM)

    - PA 37 FUSRAP Considered Sites Site: Curtiss-Wright Corp. ( PA.37 ) Eliminated from further consideration under FUSRAP - Referred to the Pennsylvania Department of Environmental Resources, Bureau of Radiation Protection Designated Name: Not Designated Alternate Name: Quehanna Site Quehanna Radioisotopes Pilot Plant Radiation Process Center PA.37-1 Location: Northwest Clearfield County , Quehanna , Pennsylvania PA.37-2 PA.37-3 Evaluation Year: Circa 1990 PA.37-1 Site Operations: 1955-1960

  10. DOE - Office of Legacy Management -- Landis Machine Tool Co - PA 34

    Office of Legacy Management (LM)

    Landis Machine Tool Co - PA 34 FUSRAP Considered Sites Site: LANDIS MACHINE TOOL CO. (PA.34 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: Teledyne Landis Machine PA.34-1 Location: Waynesboro , Pennsylvania PA.34-2 Evaluation Year: 1991 PA.34-1 Site Operations: Manufactured metal fabrication equipment for machining uranium metal slugs. PA.34-1 Site Disposition: Eliminated - Limited scope of activities performed quantities of radioactive

  11. DOE - Office of Legacy Management -- Roberts and Manders Corp - PA 28

    Office of Legacy Management (LM)

    Roberts and Manders Corp - PA 28 FUSRAP Considered Sites Site: ROBERTS AND MANDERS CORP. (PA.28 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Hatboro , Pennsylvania PA.28-1 Evaluation Year: 1987 PA.28-2 Site Operations: Research/Development operation. Company was considered a candidate for work with beryllium metal - but rejected the opportunity. PA.28-2 PA.28-3 Site Disposition: Eliminated - No indication that radioactive

  12. DOE - Office of Legacy Management -- Rohm and Hass Co - PA 02

    Office of Legacy Management (LM)

    Rohm and Hass Co - PA 02 FUSRAP Considered Sites Site: ROHM & HASS CO. (PA.02 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: 5000 Richmond Street , Philadelphia , Pennsylvania PA.02-1 Evaluation Year: 1985 PA.02-2 Site Operations: Research and development on uranium recovery from carbonate leach liquors in the mid-1950s. PA.02-3 Site Disposition: Eliminated - Radiation levels below criteria PA.02-4 Radioactive Materials Handled:

  13. WC_1992_002_CLASS_WAIVER_of_the_Government_US_and_Foreign_Pa...

    Energy Savers [EERE]

    2002CLASSWAIVERoftheGovernmentUSandForeignPa.pdf WC1992002CLASSWAIVERoftheGovernmentUSandForeignPa.pdf WC1992002CLASSWAIVERoftheGovernmentUSandForeig...

  14. DOE - Office of Legacy Management -- Meili and Worthington - PA 0-04

    Office of Legacy Management (LM)

    Meili and Worthington - PA 0-04 FUSRAP Considered Sites Site: MEILI & WORTHINGTON (PA.0-04 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Hatboro , Pennsylvania PA.0-04-1 PA.0-04-2 Evaluation Year: 1987 PA.0-04-1 Site Operations: Manufacturing facility. PA.0-04-1 Site Disposition: Eliminated - No indication radioactive material was used on this site PA.0-04-1 Radioactive Materials Handled: None Indicated PA.0-04-1 Primary

  15. Characterization of function and regulation of miR-24-1 and miR-31

    SciTech Connect (OSTI)

    Sun Fenyong; Wang Jiayi; Pan Qiuhui; Yu Yongchun; Zhang Yue; Wan Yang; Wang Ju; Li Xiaoyan; Hong An

    2009-03-13

    To date, numerous microRNAs (miRNAs) have been discovered. However, the function of these miRNAs is largely unknown. While our knowledge of miRNA post-transcriptional processing has greatly expanded in recent years, we have a limited understanding of the regulation and transcription of miRNA genes. In this study, we characterized two BMP-2 upregulated miRNAs, miR-24-1 and miR-31, in mesenchymal stem cells and showed their opposing function in controlling cellular proliferation, and adipogenesis. Furthermore, we are the first to identify and characterize mouse intronic miR-23b{approx}27b{approx}24-1 and intergenic miR-31 genes. Moreover, we found that pri-miR-23b, pri-miR-27b, and pri-miR-24-1 are transcribed independently and their expression profiles are unique when cells are treated with BMP-2, even though they are located closely together.

  16. DOE - Office of Legacy Management -- Aluminum Co of America - PA 23

    Office of Legacy Management (LM)

    PA 23 FUSRAP Considered Sites Site: Aluminum Company of America (ALCOA) ( PA.23 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: ALCOA Research Laboratory ALCOA New Kensington Works PA.23-3 PA.23-4 Location: 600 Freeport Road and Pine and Ninth Streets , New Kensington , Pennsylvania PA.23-1 PA.23-4 Evaluation Year: Circa 1993 PA.23-1 Site Operations: Research/Development and Production activities in support of the MED uranium slug canning and

  17. DOE - Office of Legacy Management -- Palmerton Ore Buying Site - PA 33

    Office of Legacy Management (LM)

    Palmerton Ore Buying Site - PA 33 FUSRAP Considered Sites Site: PALMERTON ORE BUYING SITE (PA.33) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: New Jersey Zinc Company PA.33-1 Location: Palmerton , Pennsylvania PA.33-2 Evaluation Year: 1994 PA.33-3 Site Operations: Mid-1950s - AEC leased the New Jersey Zinc Company property and established a uranium ore stockpile on the property in the vicinity of Palmerton, PA. PA.33-4 Site Disposition:

  18. DOE - Office of Legacy Management -- Dow Chemical Co - Midland - MI 06

    Office of Legacy Management (LM)

    Midland - MI 06 FUSRAP Considered Sites Site: Dow Chemical Co. - Midland (MI.06 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Midland , Michigan MI.06-1 Evaluation Year: Circa 1987 MI.06-2 Site Operations: Conducted development work for production of magnesium-thorium alloys. MI.06-1 Site Disposition: Eliminated - AEC licensed site MI.06-1 MI.06-2 Radioactive Materials Handled: Yes Primary Radioactive Materials Handled:

  19. Nitrogen effects on crystallization kinetics of amorphous TiOxNy thin films

    SciTech Connect (OSTI)

    Hukari, Kyle; Dannenberg, Rand; Stach, E.A.

    2001-03-30

    The crystallization behavior of amorphous TiOxNy (x>>y) thin films was investigated by in-situ transmission electron microscopy. The Johnson-Mehl-Avrami-Kozolog (JMAK) theory is used to determine the Avrami exponent, activation energy, and the phase velocity pre-exponent. Addition of nitrogen inhibits diffusion, increasing the nucleation temperature, while decreasing the growth activation energy. Kinetic variables extracted from individual crystallites are compared to JMAK analysis of the fraction transformed and a change of 6 percent in the activation energy gives agreement between the methods. From diffraction patterns and index of refraction the crystallized phase was found to be predominantly anatase.

  20. DOE Zero Ready Home Case Study: AquaZephyr, Eco-Vilage Ithaca, Ithaca NY

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AquaZephyr Eco-Village Ithaca Ithaca, NY DOE ZERO ENERGY READY HOME(tm) The U.S. Department of Energy invites home builders across the country to meet the extraordinary levels of excellence and quality specified in DOE's Zero Energy Ready Home program (formerly known as Challenge Home). Every DOE Zero Energy Ready Home starts with ENERGY STAR Certified Homes Version 3.0 for an energy-efficient home built on a solid foundation of building science research. Advanced technologies are designed in to

  1. DOE Zero Ready Home Case Study: Greenhill Contracting, The Preserve, New Paltz, NY

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    The Preserve New Paltz, NY DOE ZERO ENERGY READY HOME(tm) The U.S. Department of Energy invites home builders across the country to meet the extraordinary levels of excellence and quality specified in DOE's Zero Energy Ready Home program (formerly known as Challenge Home). Every DOE Zero Energy Ready Home starts with ENERGY STAR Certified Homes Version 3.0 for an energy-efficient home built on a solid foundation of building science research. Advanced technologies are designed in to give you

  2. Demonstration Assessment of LED Roadway Lighting: Philadelphia, PA

    SciTech Connect (OSTI)

    Royer, Michael P.; Tuenge, Jason R.; Poplawski, Michael E.

    2012-09-01

    For this demonstration assessment, 10 different groups of LED luminaires were installed at three sites in Philadelphia, PA. Each of the three sites represented a different set of conditions, most importantly with regard to the incumbent HPS luminaires, which were nominally 100 W, 150 W, and 250 W. The performance of each product was evaluated based on manufacturer data, illuminance calculations, field measurements of illuminance, and the subjective impressions of both regular and expert observers.

  3. QER Public Meeting in Pittsburgh, PA: Natural Gas: Transmission, Storage

    Broader source: Energy.gov (indexed) [DOE]

    and Distribution | Department of Energy 21, 2014 - 10:00 A.M. EDT Rashid Auditorium Hillman Center Carnegie Mellon University 5000 Forbes Avenue Pittsburgh, PA 15213 Parking is available for attendees in Carnegie Mellon University's East Campus Garage, accessible using the entrance at the intersection of Forbes Avenue and Devon Street. For additional information about visiting Carnegie Mellon University's campus, Click Here Meeting Information Click here to comment on the QER Public Meeting,

  4. Privacy Act (PA) of 1974 | National Nuclear Security Administration |

    National Nuclear Security Administration (NNSA)

    (NNSA) Privacy Act (PA) of 1974 The purpose of the Privacy Act of 1974 (Act), Title 5, United States Code, Section 552a, is to balance the government's need to maintain information about individuals with the rights of individuals to be protected against unwarranted invasions of their privacy stemming from federal agencies' collection, maintenance, use, and disclosure of personal information about them. Therefore, unlike the Freedom of Information Act, the Act is not a disclosure Act and is

  5. MINING PENNSYLVANIA NATIONAL ENERGY TECHNOLOGY LAB - PA POC

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    MINING PENNSYLVANIA NATIONAL ENERGY TECHNOLOGY LAB - PA POC Larry Sullivan Telephone (412) 386-6115 Email larry.sullivan@netl.doe.gov Support Activities for Oil and Gas Operations 213112 WEST VIRGINIA NATIONAL ENERGY TECHNOLOGY LAB -WV POC Larry Sullivan Telephone (412) 386-6115 Email larry.sullivan@netl.doe.gov Support Activities for Oil and Gas Operations 213112 WYOMING ROCKY MOUNTAIN OILFIELD CENTER POC Jenny Krom Telephone (307) 233-4818 Email jenny.krom@rmotc.doe.gov Support Activities for

  6. Designation Survey - Palmerton, Pa. Ore Storage Site William Bibb

    Office of Legacy Management (LM)

    Designation Survey - Palmerton, Pa. Ore Storage Site William Bibb Oak Ridge Operations Office Based on the information furnished in Aerospace's Review of the.subject site (Attachment 1) and the ORKL/RASA (Attachment 2), it Is requested that designation survey of the Palmerton Ore Storage Pennsylvania. The survey should be detailed to and subsurface data to make up for the lack of the previous AEC surveys and in keeping with ORNL/RASA group should furnish a draft survey approval prior to

  7. DOE - Office of Legacy Management -- University of Pennsylvania - PA 0-06

    Office of Legacy Management (LM)

    Pennsylvania - PA 0-06 FUSRAP Considered Sites Site: UNIVERSITY OF PENNSYLVANIA (PA.0-06 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Philadelphia , Pennsylvania PA.0-06-1 Evaluation Year: 1987 PA.0-06-1 Site Operations: Research activities involving small quantities of radioactive materials in a controlled environment. PA.0-06-1 Site Disposition: Eliminated - Potential for residual radioactive contamination considered remote

  8. DOE - Office of Legacy Management -- University of Pittsburgh - PA 0-07

    Office of Legacy Management (LM)

    Pittsburgh - PA 0-07 FUSRAP Considered Sites Site: UNIVERSITY OF PITTSBURGH (PA.0-07) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Pittsburgh , Pennsylvania PA.0-07-1 Evaluation Year: 1987 PA.0-07-1 Site Operations: Research activities involving small quantities of radioactive materials in a controlled environment. PA.0-07-1 Site Disposition: Eliminated - Potential for residual radioactive contamination considered remote

  9. DOE - Office of Legacy Management -- Westinghouse Atomic Power Div - PA 16

    Office of Legacy Management (LM)

    Power Div - PA 16 FUSRAP Considered Sites Site: WESTINGHOUSE ATOMIC POWER DIV. (PA.16 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Route 30 (Forrest Hills) , Pittsburgh , Pennsylvania PA.16-1 Evaluation Year: 1985 PA.16-1 Site Operations: Processed uranium metal for research and development and pilot-scale production of uranium oxide fuel elements. Prepared uranium metal for Enrico Fermi's Stagg Field experiment. PA.16-1 Site

  10. DOE - Office of Legacy Management -- General Motors Co - Flint - MI 07

    Office of Legacy Management (LM)

    Motors Co - Flint - MI 07 FUSRAP Considered Sites Site: GENERAL MOTORS CO. (MI.07 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: A.C. Spark Plug Dort Highway Plant MI.07-1 MI.07-2 Location: Flint , Michigan MI.07-1 Evaluation Year: 1987 MI.07-3 Site Operations: Processed thorium oxide, uranium oxide, and beryllium oxide into crucibles for the Chicago Area. MI.07-3 MI.07-4 MI.07-5 Site Disposition: Eliminated - Potential for contamination

  11. MINOS Experiment and NuMI Beam Home Page

    Broader source: All U.S. Department of Energy (DOE) Office Webpages

    NuMI-MINOS Neutrino Logo NuMI Beamline and MINOS Experiment Neutrino Logo The MINOS Experiment and NuMI Beamline Fermilab Logo MINOS Experiment Links ◊ MINOS for the Public ◊ Scientific Results ◊ MINOS at Work ◊ NuMI at Work ◊ MINOS+ Experiment Fermilab Neutrino Links ◊ Neutrino FAQ ◊ MINOS Underground Areas at Fermilab ◊ PPD Intensity Frontier Dept Back to - - - ◊ Fermilab at Work ◊ Fermilab Home the MINOS Far Detector in the Soudan Mine MINOS collaborators assembling the

  12. Magnetocrystalline anisotropy in <mi>UMn>2<mi>Ge>2 and related Mn-based actinide ferromagnets

    SciTech Connect (OSTI)

    Parker, David S.; Ghimire, Nirmal; Singleton, John; Thompson, J. D.; Bauer, Eric D.; Baumbach, Ryan; Mandrus, David; Li, Ling; Singh, David J.

    2015-05-04

    We present magnetization isotherms in pulsed magnetic fields up to 62 Tesla, supported by first principles calculations, demonstrating a huge uniaxial magnetocrystalline anisotropy energy - approximately 20 MJ/m3 - in <mi>UMn>2<mi>Ge>2. This large anisotropy results from the extremely strong spin-orbit coupling affecting the uranium 5 f electrons, which in the calculations exhibit a substantial orbital moment exceeding 2 μB. Finally, we also find from theoretical calculations that a number of isostructural Mn-actinide compounds are expected to have similarly large anisotropy.

  13. ,"Detroit, MI Natural Gas Pipeline Imports From Canada (MMcf...

    U.S. Energy Information Administration (EIA) Indexed Site

    ,"Worksheet Name","Description"," Of Series","Frequency","Latest Data for" ,"Data 1","Detroit, MI Natural Gas Pipeline Imports From Canada (MMcf)",1,"Annual",2014 ,"Release...

  14. DOE - Office of Legacy Management -- Paul and Beekman - PA 0-05

    Office of Legacy Management (LM)

    Paul and Beekman - PA 0-05 FUSRAP Considered Sites Site: PAUL AND BEEKMAN (PA.0-05) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Philadelphia , Pennsylvania PA.0-05-1 Evaluation Year: 1987 PA.0-05-1 Site Operations: Produced aluminum cans for AEC slug development program. PA.0-05-1 Site Disposition: Eliminated - No indication radioactive material was used at the site PA.0-05-1 Radioactive Materials Handled: None Indicated

  15. State College Area High School From State College, PA Wins DOE...

    Office of Environmental Management (EM)

    College Area High School From State College, PA Wins DOE's National Science Bowl State College Area High School From State College, PA Wins DOE's National Science Bowl May 1, ...

  16. The origin and fate of the sediments composing a migrating dune field, Amagansett, NY

    SciTech Connect (OSTI)

    Maher, T. (Suffolk Community Coll., Selden, NY (United States). Environmental Science Dept.); Kandelin, J. (Suffolk Community Coll., Selden, NY (United States). Dept. of Earth and Space Science); Black, J.A. (Geosciences Inc., Patchogue, NY (United States))

    1993-03-01

    The migrating dune system, located in Amagansett, NY, consists of a series of three parabolic dunes ranging in heights from 10 to 30 meters. The dunes are migrating under the influence of the prevailing winds, in a southeasterly direction. The migration continues until the dunes encounter the countervailing prevailing winds, off the Atlantic Ocean. A series of flow charts have been prepared to indicate the possible sources of sediment for this system. These charts, in conjunction with geomorphic analysis, stratigraphic data and various sediment characteristics indicate that the sediments are transported by coastal currents. Once deposited they form a linear dune system. Eolian transport from this dune then supplies the sediment to the migrating dune system.

  17. Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells

    SciTech Connect (OSTI)

    Vrba, Lukas; Jensen, Taylor J.; Garbe, James C.; Heimark, Ronald L.; Cress, Anne E.; Dickinson, Sally; Stampfer, Martha R.; Futscher, Bernard W.

    2009-12-23

    BACKGROUND: The microRNA-200 family participates in the maintenance of an epithelial phenotype and loss of its expression can result in epithelial to mesenchymal transition (EMT). Furthermore, the loss of expression of miR-200 family members is linked to an aggressive cancer phenotype. Regulation of the miR-200 family expression in normal and cancer cells is not fully understood. METHODOLOGY/ PRINCIPAL FINDINGS: Epigenetic mechanisms participate in the control of miR-200c and miR-141 expression in both normal and cancer cells. A CpG island near the predicted mir-200c/mir-141 transcription start site shows a striking correlation between miR-200c and miR-141 expression and DNA methylation in both normal and cancer cells, as determined by MassARRAY technology. The CpG island is unmethylated in human miR-200/miR-141 expressing epithelial cells and in miR-200c/miR-141 positive tumor cells. The CpG island is heavily methylated in human miR-200c/miR-141 negative fibroblasts and miR-200c/miR-141 negative tumor cells. Mouse cells show a similar inverse correlation between DNA methylation and miR-200c expression. Enrichment of permissive histone modifications, H3 acetylation and H3K4 trimethylation, is seen in normal miR-200c/miR-141-positive epithelial cells, as determined by chromatin immunoprecipitation coupled to real-time PCR. In contrast, repressive H3K9 dimethylation marks are present in normal miR-200c/miR-141-negative fibroblasts and miR-200c/miR-141 negative cancer cells and the permissive histone modifications are absent. The epigenetic modifier drug, 5-aza-2'-deoxycytidine, reactivates miR-200c/miR-141 expression showing that epigenetic mechanisms play a functional role in their transcriptional control. CONCLUSIONS/ SIGNIFICANCE: We report that DNA methylation plays a role in the normal cell type-specific expression of miR-200c and miR-141 and this role appears evolutionarily conserved, since similar results were obtained in mouse. Aberrant DNA methylation of the

  18. DOE - Office of Legacy Management -- Vanadium Corp of America - PA 15

    Office of Legacy Management (LM)

    Vanadium Corp of America - PA 15 Site ID (CSD Index Number): PA.15 Site Name: Vanadium Corp. of America Site Summary: Site Link: http://www.lm.doe.gov/canonsburg/Sites.aspx External Site Link: Alternate Name(s): UMTRAP Vicinity Property No. CA-401 Vanadium Corp of America Alternate Name Documents: PA.15-5 Location: Mayer Street - Collier Township , Bridgeville , Pennsylvania Location Documents: PA.15-1 Historical Operations (describe contaminants): Faclility used to grind pitchblende ore during

  19. miR-92a family and their target genes in tumorigenesis and metastasis

    SciTech Connect (OSTI)

    Li, Molin; Guan, Xingfang; Sun, Yuqiang; Mi, Jun; Shu, Xiaohong; Liu, Fang; Li, Chuangang

    2014-04-15

    The miR-92a family, including miR-25, miR-92a-1, miR-92a-2 and miR-363, arises from three different paralog clusters miR-17-92, miR-106a-363, and miR-106b-25 that are highly conservative in the process of evolution, and it was thought as a group of microRNAs (miRNAs) correlated with endothelial cells. Aberrant expression of miR-92a family was detected in multiple cancers, and the disturbance of miR-92a family was related with tumorigenesis and tumor development. In this review, the progress on the relationship between miR-92a family and their target genes and malignant tumors will be summarized. - Highlights: Aberrant expression of miR-92a, miR-25 and miR-363 can be observed in many kinds of malignant tumors. The expression of miR-92a family is regulated by LOH, epigenetic alteration, transcriptional factors such as SP1, MYC, E2F, wild-type p53 etc. Roles of miR-92a family in tumorigenesis and development: promoting cell proliferation, invasion and metastasis, inhibiting cell apoptosis.

  20. F-1 U.S. Energy Information Administration | Annual Energy Outlook...

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    Central West North Central East North Central Mountain AK WA MT WY ID NV UT CO AZ NM TX OK IA KS MO IL IN KY TN MS AL FL GA SC NC WV PA NJ MD DE NY CT VT ME RI MA NH VA WI MI OH...

  1. F-5 U.S. Energy Information Administration | Annual Energy Outlook...

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    Figure F4. Oil and Gas Supply Model Regions Atlantic WA MT WY ID NV UT CO AZ NM TX OK IA KS MO IL IN KY TN MS AL FL GA SC NC WV PA NJ MD DE NY CT ME RI MA NH VA WI MI OH NE...

  2. Chapter V

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... AL LA GA AR NC NY MI PA IN VA MS TN KY OH ME SC WV MD VT MA NH CT NJ DE R I DC b Coal Fired Power Plant Supplied by the Powder River Basin Powder River Basin 0 220 110 Miles The ...

  3. DOE - Office of Legacy Management -- Baker-Perkins Co - MI 13

    Office of Legacy Management (LM)

    Baker-Perkins Co - MI 13 FUSRAP Considered Sites Site: Baker-Perkins Co (MI 13) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Saginaw , Michigan MI.13-1 Evaluation Year: 1991 MI.13-1 MI.13-2 Site Operations: Small scale oxide mixing demonstrations and testing in May, 1956. MI.13-2 Site Disposition: Eliminated - Potential for contamination remote based on limited scope of activities at the site MI.13-3 Radioactive Materials Handled: Yes

  4. DOE - Office of Legacy Management -- Revere Copper and Brass Co - MI 04

    Office of Legacy Management (LM)

    Revere Copper and Brass Co - MI 04 FUSRAP Considered Sites Site: REVERE COPPER AND BRASS CO. ( MI.04 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: Revere Copper and Brass MI.04-1 Location: 5851 West Jefferson Street , Detroit , Michigan MI.04-1 Evaluation Year: 1990 MI.04-2 Site Operations: Extrusion of tuballoy rods, myrnalloy rods and beryllium shapes in the 1940s. MI.04-3 MI.04-4 Site Disposition: Eliminated - Radiation levels below criteria

  5. HIA 2015 DOE Zero Energy Ready Home Case Study: United Way of Long Island Housing Development Corporation, Patchogue, NY

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Way of Long Island Housing Development Corporation Patchogue, NY DOE ZERO ENERGY READY HOME(tm) The U.S. Department of Energy invites home builders across the country to meet the extraordinary levels of excellence and quality specified in DOE's Zero Energy Ready Home program (formerly known as Challenge Home). Every DOE Zero Energy Ready Home starts with ENERGY STAR Certified Homes Version 3.0 for an energy-efficient home built on a solid foundation of building science research. Advanced

  6. Origin State>> CA ID ID ID IL MD NM NM NY OH TN TN TN, WA, CA

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NY OH TN TN TN, WA, CA TN TN TN TX Total Shipments by Route Lawrence Livermore National Laboratory Batelle Energy Alliance Idaho National Laboratory Advanced Mixed Waste Treatment Project Argonne National Laboratory Aberdeen Proving Ground Sandia National Laboratory Los Alamos National Laboratory Brookhaven National Laboratory Portsmouth Gaseous Diffusion Plant Duratek/Energy Solutions Babcox & Wilcox Technical Services Y-12 Plant Materials & Energy Corporation (M&EC) Perma-Fix

  7. Origin State>> CA ID ID IL IL KY NM NM NV NY OH TN TN TN, WA,

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    IL IL KY NM NM NV NY OH TN TN TN, WA, CA TN TN TN TN Total Shipments by Route Lawrence Livermore National Laboratory Batelle Energy Alliance Idaho National Laboratory Energx Argonne National Laboratory Argonne National Laboratory Paducah Gaseous Diffusion Plant Sandia National Laboratory Los Alamos National Laboratory National Security Technologies West Valley Environmental Services Portsmouth Gaseous Diffusion Plant Duratek/Energy Solutions Babcox & Wilcox Technical Services Y-12 Plant

  8. miR-17 inhibitor suppressed osteosarcoma tumor growth and metastasis via increasing PTEN expression

    SciTech Connect (OSTI)

    Gao, Yong; Luo, Ling-hui; Li, Shuai; Yang, Cao

    2014-02-07

    Highlights: • miR-17 was increased in OS tissues and cell lines. • Inhibition of miR-17 suppressed OS cell proliferation. • Inhibition of miR-17 suppressed OS cell migration and invasion. • PTEN was a target of miR-17. • miR-17 was negatively correlated with PTEN in OS tissues. - Abstract: MicroRNAs (miRNAs) play essential roles in cancer development and progression. Here, we investigated the role of miR-17 in the progression and metastasis of osteosarcoma (OS). miR-17 was frequently increased in OS tissues and cell lines. Inhibition of miR-17 in OS cell lines substantially suppressed cell proliferation, migration, and invasion. Phosphatase and tensin homolog (PTEN) was identified as a target of miR-17, and ectopic expression of miR-17 inhibited PTEN by direct binding to its 3′-untranslated region (3′-UTR). Expression of miR-17 was negatively correlated with PTEN in OS tissues. Together, these findings indicate that miR-17 acts as an oncogenic miRNA and may contribute to the progression and metastasis of OS, suggesting miR-17 as a potential novel diagnostic and therapeutic target of OS.

  9. Local Teams from PA, WV Travel to Washington D.C. for National Science Bowl

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    | netl.doe.gov Regional News Local Teams from PA, WV Travel to Washington D.C. for National Science Bowl Pittsburgh, Pa. - The National Energy Technology Laboratory have sent the regional winners of the southwestern Pennsylvania (SWPA) and West Virginia Science Bowls off to compete in the U.S. Department of Energy National Science Bowl April 28-May 2, 2016, in Washington, D.C. By winning their regional tournaments, the Marshall Middle School (Wexford, PA), Morgantown High School (Morgantown,

  10. EERE PROJECT MANAGEMENT CENTER Nl!PA DFTFnIINATION RECIPIENT...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Il.II.': , u.s. DEPARTMENT OFFNERGY EERE PROJECT MANAGEMENT CENTER NlPA DFTFnIINATION ... publication, and distribution: and classroom training and informational programs), ...

  11. MiR-218 Mediates tumorigenesis and metastasis: Perspectives and implications

    SciTech Connect (OSTI)

    Lu, Ying-fei; Zhang, Li; Waye, Mary Miu Yee; Fu, Wei-ming; Zhang, Jin-fang

    2015-05-15

    MicroRNAs (miRNAs) are a class of small non-coding RNAs that negatively regulate gene expression at the post-transcriptional level. As a highly conserved miRNA across a variety of species, microRNA-218 (miR-218) was found to play pivotal roles in tumorigenesis and progression. A group of evidence has demonstrated that miR-218 acts as a tumor suppressor by targeting many oncogenes related to proliferation, apoptosis and invasion. In this review, we provide a complex overview of miR-218, including its regulatory mechanisms, known functions in cancer and future challenges as a potential therapeutic target in human cancers. - Highlights: • miR-218 is frequently down regulated in multiple cancers. • miR-218 plays pivotal roles in carcinogenesis. • miR-218 mediates proliferation, apoptosis, metastasis, invasion, etc. • miR-218 mediates tumorigenesis and metastasis via multiple pathways.

  12. DOE - Office of Legacy Management -- Dow-Detroit Edison Project - MI 0-02

    Office of Legacy Management (LM)

    Dow-Detroit Edison Project - MI 0-02 FUSRAP Considered Sites Site: Dow-Detroit Edison Project (MI.0-02 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Detroit , Michigan MI.0-02-1 Evaluation Year: 1987 MI.0-02-1 Site Operations: Performed reference design work for a special fast breeder type reactor. MI.0-02-1 Site Disposition: Eliminated - No radioactive material handled at the site MI.0-02-1 Radioactive Materials Handled: No

  13. DOE - Office of Legacy Management -- Mitts-Merrill Co - MI 14

    Office of Legacy Management (LM)

    Mitts-Merrill Co - MI 14 FUSRAP Considered Sites Site: MITTS and MERRILL CO. (MI.14 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: Genessee Packing Co. MI.14-1 Location: Saginaw, Michigan MI.14-1 Evaluation Year: 1993 MI.14-2 Site Operations: Reduced thorium metal chunks into particle sized pieces on a small test scale during the mid-1950s. MI.14-1 Site Disposition: Eliminated - Potential for contamination considered remote based on limited quantity

  14. miRNA-205 affects infiltration and metastasis of breast cancer

    SciTech Connect (OSTI)

    Wang, Zhouquan; Department of Tumor, SenGong Hospital of Shaanxi, Xian 710300 ; Liao, Hehe; Deng, Zhiping; Yang, Po; Du, Ning; Zhanng, Yunfeng; Ren, Hong

    2013-11-08

    Highlights: We detected expression of miR-205 in breast cancer cell lines and tissue samples. We suggest miR-205 is downregulated in human breast cancer tissues and MCF7 cells. We suggest the lower expression of miR-205 play a role in breast cancer onset. These data suggest that miR-205 directly targets HER3 in human breast cancer. -- Abstract: Background: An increasing number of studies have shown that miRNAs are commonly deregulated in human malignancies, but little is known about the function of miRNA-205 (miR-205) in human breast cancer. The present study investigated the influence of miR-205 on breast cancer malignancy. Methods: The expression level of miR-205 in the MCF7 breast cancer cell line was determined by quantitative (q)RT-PCR. We then analyzed the expression of miR-205 in breast cancer and paired non-tumor tissues. Finally, the roles of miR-205 in regulating tumor proliferation, apoptosis, migration, and target gene expression were studied by MTT assay, flow cytometry, qRT-PCR, Western blotting and luciferase assay. Results: miR-205 was downregulated in breast cancer cells or tissues compared with normal breast cell lines or non-tumor tissues. Overexpression of miR-205 reduced the growth and colony-formation capacity of MCF7 cells by inducing apoptosis. Overexpression of miR-205 inhibited MCF7 cell migration and invasiveness. By bioinformation analysis, miR-205 was predicted to bind to the 3? untranslated regions of human epidermal growth factor receptor (HER)3 mRNA, and upregulation of miR-205 reduced HER3 protein expression. Conclusion: miR-205 is a tumor suppressor in human breast cancer by post-transcriptional inhibition of HER3 expression.

  15. HIA 2015 DOE Zero Energy Ready Home Case Study: Greenhill Contracting, Green Acres #20, #26, #28, New Paltz, NY

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Green Acres #20, #26, #28 New Paltz, NY DOE ZERO ENERGY READY HOME(tm) The U.S. Department of Energy invites home builders across the country to meet the extraordinary levels of excellence and quality specified in DOE's Zero Energy Ready Home program (formerly known as Challenge Home). Every DOE Zero Energy Ready Home starts with ENERGY STAR Certified Homes Version 3.0 for an energy-efficient home built on a solid foundation of building science research. Advanced technologies are designed in to

  16. NuMI Low Energy Flux Prediction Release

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NuMI Low Energy Flux Prediction Release Neutrino Flux Predictions for the NuMI Beam hep-ex/1607.00704 Data Ancillary data files for this result are available on arXiv at http://arxiv.org/src/1607.00704/anc.< /li> Among the available data files are: pdf file describing format of all the available files root file of all the available fluxes python code to read and process MINERvA's flux predictions Text Files of the flux, uncertainties, and covariance matrix, with units of neutrinos/m^2/POT,

  17. Port Huron, MI Liquefied Natural Gas Exports (Million Cubic Feet)

    U.S. Energy Information Administration (EIA) Indexed Site

    (Million Cubic Feet) Port Huron, MI Liquefied Natural Gas Exports (Million Cubic Feet) Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2013 1 2014 1 1 1 1 2 1 1 1 1 1 2015 1 1 1 1 1 - = No Data Reported; -- = Not Applicable; NA = Not Available; W = Withheld to avoid disclosure of individual company data. Release Date: 08/31/2016 Next Release Date: 09/30/2016 Referring Pages: U.S. Liquefied Natural Gas Exports by Point of Exit Port Huron, MI LNG Exports to All Countries

  18. Ground Motion Studies at NuMI

    SciTech Connect (OSTI)

    Mayda M. Velasco; Michal Szleper

    2012-02-20

    Ground motion can cause significant deterioration in the luminosity of a linear collider. Vibration of numerous focusing magnets causes continuous misalignments, which makes the beam emittance grow. For this reason, understanding the seismic vibration of all potential LC sites is essential and related efforts in many sites are ongoing. In this document we summarize the results from the studies specific to Fermilab grounds as requested by the LC project leader at FNAL, Shekhar Mishra in FY04-FY06. The Northwestern group focused on how the ground motion effects vary with depth. Knowledge of depth dependence of the seismic activity is needed in order to decide how deep the LC tunnel should be at sites like Fermilab. The measurements were made in the NuMI tunnel, see Figure 1. We take advantage of the fact that from the beginning to the end of the tunnel there is a height difference of about 350 ft and that there are about five different types of dolomite layers. The support received allowed to pay for three months of salary of Michal Szleper. During this period he worked a 100% of his time in this project. That include one week of preparation: 2.5 months of data taking and data analysis during the full period of the project in order to guarantee that we were recording high quality data. We extended our previous work and made more systematic measurements, which included detailed studies on stability of the vibration amplitudes at different depths over long periods of time. As a consequence, a better control and more efficient averaging out of the daytime variation effects were possible, and a better study of other time dependences before the actual depth dependence was obtained. Those initial measurements were made at the surface and are summarized in Figure 2. All measurements are made with equipment that we already had (two broadband seismometers KS200 from GEOTECH and DL-24 portable data recorder). The offline data analysis took advantage of the full Fourier spectra

  19. DOE - Office of Legacy Management -- Mitts-Merrel Co - MI 14

    Office of Legacy Management (LM)

    1993 MI.14-2 Site Operations: Reduced thorium metal chunks into particle sized pieces ... Primary Radioactive Materials Handled: Thorium MI.14-1 Radiological Survey(s): Yes - ...

  20. Albany, OR * Anchorage, AK * Morgantown, WV * Pittsburgh, PA * Sugar Land, TX

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GSRA CONTACTS Traci Rodosta Carbon Storage Technology Manager National Energy Technology Laboratory 3610 Collins Ferry Road P.O. Box 880 Morgantown, WV 26507 304-285-1345 traci.rodosta@netl.doe.gov Andrea McNemar Project Manager National Energy Technology Laboratory 3610 Collins Ferry Road P.O. Box 880 Morgantown, WV 26507 304-285-2024 andrea.mcnemar@netl.doe.gov Constantin Cranganu Principal Investigator Brooklyn College 2900 Bedford Avenue 4415 Ingersoll Hall Brooklyn, NY 11210 718-951-5000

  1. MiR-125a TNF receptor-associated factor 6 to inhibit osteoclastogenesis

    SciTech Connect (OSTI)

    Guo, Li-Juan; Liao, Lan; Yang, Li; Li, Yu; Jiang, Tie-Jian

    2014-02-15

    MicroRNAs (miRNAs) play important roles in osteoclastogenesis and bone resorption. In the present study, we found that miR-125a was dramatically down-regulated during macrophage colony stimulating factor (M-CSF) and receptor activator of nuclear factor-κB ligand (RANKL) induced osteoclastogenesis of circulating CD14+ peripheral blood mononuclear cells (PBMCs). Overexpression of miR-125a in CD14+ PBMCs inhibited osteoclastogenesis, while inhibition of miR-125a promoted osteoclastogenesis. TNF receptor-associated factor 6 (TRAF6), a transduction factor for RANKL/RANK/NFATc1 signal, was confirmed to be a target of miR-125a. EMSA and ChIP assays confirmed that NFATc1 bound to the promoter of the miR-125a. Overexpression of NFATc1 inhibited miR-125a transcription, and block of NFATc1 expression attenuated RANKL-regulated miR-125a transcription. Here, we reported that miR-125a played a biological function in osteoclastogenesis through a novel TRAF6/ NFATc1/miR-125a regulatory feedback loop. It suggests that regulation of miR-125a expression may be a potential strategy for ameliorating metabolic disease. - Highlights: • MiR-125a was significantly down-regulated in osteoclastogenesis of CD14+ PBMCs. • MiR-125a inhibited osteoclast differentiation by targeting TRAF6. • NFATc1 inhibited miR-125a transciption by binding to the promoter of miR-125a. • TRAF6/NFATc1 and miR-125a form a regulatory feedback loop in osteoclastogenesis.

  2. DOE - Office of Legacy Management -- Amex Specialty Metal Corp - MI 0-01

    Office of Legacy Management (LM)

    Amex Specialty Metal Corp - MI 0-01 FUSRAP Considered Sites Site: Amex Specialty Metal Corp (MI.0-01 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Coldwater , Michigan MI.0-01-1 Evaluation Year: 1987 MI.0-01-1 Site Operations: No indication that AMEX performed work for MED or AEC activities. Originally included on FUSRAP list due to fact that AMEX purchased milling equipment from a company that had done uranium milling.

  3. Vehicle Technologies Office Merit Review 2016: BatPaC Model Development |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy BatPaC Model Development Vehicle Technologies Office Merit Review 2016: BatPaC Model Development Presentation given by Argonne National Laboratory (ANL) at the 2016 DOE Vehicle Technologies Office and Hydrogen and Fuel Cells Program Annual Merit Review and Peer Evaluation Meeting about Batteries es228_ahmed_2016_o_web.pdf (1.17 MB) More Documents & Publications Vehicle Technologies Office Merit Review 2015: BatPaC Model Development Vehicle Technologies Office Merit

  4. MiR-145 functions as a tumor suppressor targeting NUAK1 in human intrahepatic cholangiocarcinoma

    SciTech Connect (OSTI)

    Xiong, Xinkui; Sun, Daoyi; Chai, Hao; Shan, Wengang; Yu, Yue; Pu, Liyong; Cheng, Feng

    2015-09-18

    The dysregulation of micro (mi)RNAs is associated with cancer development. The miRNA miR-145 is downregulated in intrahepatic cholangiocarcinoma (ICC); however, its precise role in tumor progression has not yet been elucidated. Novel (nua) kinase family (NUAK)1 functions as an oncogene in various cancers and is a putative target of miR-145 regulation. In this study, we investigated the regulation of NUAK1 by miR-145 in ICC. We found that miR-145 level was significantly decreased in ICC tissue and cell lines, which corresponded with an increase in NUAK1 expression. NUAK1 was found to be a direct target of miR-145 regulation. The overexpression of miR-145 in ICC cell lines inhibited proliferation, growth, and invasion by suppressing NUAK1 expression, which was associated with a decrease in Akt signaling and matrix metalloproteinase protein expression. Similar results were observed by inhibiting NUAK1 expression. These results demonstrate that miR-145 can prevent ICC progression by targeting NUAK1 and its downstream effectors, and can therefore be useful for clinical diagnosis and targeted therapy of ICC. - Highlights: • MiR-145 suppresses ICC proliferation and invasion abilities. • We demonstrated that miR-145 directly targets NUAK1 in ICC. • MiR-145 expression in ICC was associated with Akt signaling and MMPs expression.

  5. Neutron scattering study of spin ordering and stripe pinning in superconducting <mi>La>1.93<mi>Sr>0.07<mi>CuO>4

    SciTech Connect (OSTI)

    Jacobsen, H.; Zaliznyak, I. A.; Savici, A. T.; Winn, B. L.; Chang, S.; Hücker, M.; Gu, G. D.; Tranquada, J. M.

    2015-11-20

    The relationships among charge order, spin fluctuations, and superconductivity in underdoped cuprates remain controversial. We use neutron scattering techniques to study these phenomena in <mi>La>1.93<mi>Sr>0.07<mi>CuO>4 a superconductor with a transition temperature of Tc = 20 K. At T<< Tc, we find incommensurate spin fluctuations with a quasielastic energy spectrum and no sign of a gap within the energy range from 0.2 to 15 meV. A weak elastic magnetic component grows below ~ 10 K, consistent with results from local probes. Regarding the atomic lattice, we have discovered unexpectedly strong fluctuations of the CuO6 octahedra about Cu-O bonds, which are associated with inequivalent O sites within the CuO2 planes. Moreover, we observed a weak elastic (3 30) superlattice peak that implies a reduced lattice symmetry. The presence of inequivalent O sites rationalizes various pieces of evidence for charge stripe order in underdoped La2-xSrxCuO4. The coexistence of superconductivity with quasi-static spin-stripe order suggests the presence of intertwined orders; however, the rotation of the stripe orientation away from the Cu-O bonds might be connected with evidence for a finite gap at the nodal points of the superconducting gap function.

  6. Radiosensitizing Effects of Ectopic miR-101 on Non-Small-Cell Lung Cancer Cells Depend on the Endogenous miR-101 Level

    SciTech Connect (OSTI)

    Chen, Susie; Wang Hongyan; Ng, Wooi Loon; Curran, Walter J.; Wang Ya

    2011-12-01

    Purpose: Previously, we showed that ectopic miR-101 could sensitize human tumor cells to radiation by targeting ATM and DNA-PK catalytic subunit (DNA-PKcs) to inhibit DNA repair, as the endogenous miR-101 levels are low in tumors in general. However, the heterogeneity of human cancers may result in an exception. The purpose of this study was to test the hypothesis that a few tumor cell lines with a high level of endogenous miR-101 would prove less response to ectopic miR-101. Methods and Materials: Fourteeen non-small-cell lung cancer (NSCLC) cell lines and one immortalized non-malignant lung epithelial cell line (NL20) were used for comparing endogenous miR-101 levels by real-time reverse transcription-polymerase chain reaction. Based on the different miR-101 levels, four cell lines with different miR-101 levels were chosen for transfection with a green fluorescent protein-lentiviral plasmid encoding miR-101. The target protein levels were measured by using Western blotting. The radiosensitizing effects of ectopic miR-101 on these NSCLC cell lines were determined by a clonogenic assay and xenograft mouse model. Results: The endogenous miR-101 level was similar or lower in 13 NSCLC cell lines but was 11-fold higher in one cell line (H157) than in NL20 cells. Although ectopic miR-101 efficiently decreased the ATM and DNA-PKcs levels and increased the radiosensitization level in H1299, H1975, and A549 cells, it did not change the levels of the miR-101 targets or radiosensitivity in H157 cells. Similar results were observed in xenograft mice. Conclusions: A small number of NSCLC cell lines could have a high level of endogenous miR-101. The ectopic miR-101 was able to radiosensitize most NSCLC cells, except for the NSCLC cell lines that had a much higher endogenous miR-101 level. These results suggest that when we choose one miRNA as a therapeutic tool, the endogenous level of the miRNA in each tumor should be considered.

  7. Vehicle Technologies Office Merit Review 2015: BatPaC Model Development

    Broader source: Energy.gov [DOE]

    Presentation given by Argonne National Laboratory at 2015 DOE Hydrogen and Fuel Cells Program and Vehicle Technologies Office Annual Merit Review and Peer Evaluation Meeting about BatPaC model...

  8. 01 Team Black_Presentation _LANL?s PaScalBB IO.pptx

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    multiple 10-Gigabit Ethernet bonding Small-scale PaScalBB test bed and conduct a sequence of IO node performance tests. Discovery of enhanced IO node network...

  9. File:USDA-CE-Production-GIFmaps-PA.pdf | Open Energy Information

    Open Energy Info (EERE)

    PA.pdf Jump to: navigation, search File File history File usage Pennsylvania Ethanol Plant Locations Size of this preview: 776 600 pixels. Full resolution (1,650 1,275...

  10. DOE - Office of Legacy Management -- Penn Central Transportation Co - PA 06

    Office of Legacy Management (LM)

    Central Transportation Co - PA 06 FUSRAP Considered Sites Site: Penn Central Transportation Co. (PA.06) Licensed to DOE for long-term custody and managed by the Office of Legacy Management. Designated Name: Burrell, Pennsylvania, Disposal Site Alternate Name: Penn Central Transportation Co. Location: Blairsville, Pennsylvania Evaluation Year: Site Operations: Site Disposition: Uranium Mill Tailings Radiation Control Act (UMTRCA) Title I site. Radioactive Materials Handled: Primary Radioactive

  11. Albany, OR * Anchorage, AK * Morgantown, WV * Pittsburgh, PA * Sugar Land, TX

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    CONTACTS J. Alexandra Hakala Geosciences Division Engineered Natural Systems Division National Energy Technology Laboratory 626 Cochrans Mill Road P.O. Box 10940 Pittsburgh, PA 15236-0940 412-386-5487 Alexandra.Hakala@netl.doe.gov George Guthrie Geological and Environmental Sciences Focus Area Leader Office of Research and Development National Energy Technology Laboratory 626 Cochrans Mill Road P.O. Box 10940 Pittsburgh, PA 15236-0940 412-386-6571 George.Guthrie@netl.doe.gov PARTNERS Carnegie

  12. State College Area High School From State College, PA Wins DOE's National

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Science Bowl® | Department of Energy College Area High School From State College, PA Wins DOE's National Science Bowl® State College Area High School From State College, PA Wins DOE's National Science Bowl® May 1, 2006 - 10:34am Addthis WASHINGTON , DC - State College Area High School from State College, Pennsylvania, today won the Department of Energy's (DOE) National Science Bowl®. Teams representing 65 schools from across the United States competed in this "Science Jeopardy"

  13. DLEU2, frequently deleted in malignancy, functions as a critical host gene of the cell cycle inhibitory microRNAs miR-15a and miR-16-1

    SciTech Connect (OSTI)

    Lerner, Mikael; Harada, Masako; Loven, Jakob; Castro, Juan; Davis, Zadie; Oscier, David; Henriksson, Marie; Sangfelt, Olle; Grander, Dan; Corcoran, Martin M.

    2009-10-15

    The microRNAs miR-15a and miR-16-1 are downregulated in multiple tumor types and are frequently deleted in chronic lymphocytic leukemia (CLL), myeloma and mantle cell lymphoma. Despite their abundance in most cells the transcriptional regulation of miR-15a/16-1 remains unclear. Here we demonstrate that the putative tumor suppressor DLEU2 acts as a host gene of these microRNAs. Mature miR-15a/miR-16-1 are produced in a Drosha-dependent process from DLEU2 and binding of the Myc oncoprotein to two alterative DLEU2 promoters represses both the host gene transcript and levels of mature miR-15a/miR-16-1. In line with a functional role for DLEU2 in the expression of the microRNAs, the miR-15a/miR-16-1 locus is retained in four CLL cases that delete both promoters of this gene and expression analysis indicates that this leads to functional loss of mature miR-15a/16-1. We additionally show that DLEU2 negatively regulates the G1 Cyclins E1 and D1 through miR-15a/miR-16-1 and provide evidence that these oncoproteins are subject to miR-15a/miR-16-1-mediated repression under normal conditions. We also demonstrate that DLEU2 overexpression blocks cellular proliferation and inhibits the colony-forming ability of tumor cell lines in a miR-15a/miR-16-1-dependent way. Together the data illuminate how inactivation of DLEU2 promotes cell proliferation and tumor progression through functional loss of miR-15a/miR-16-1.

  14. Genome-Wide Analysis of miRNA targets in Brachypodium and Biomass Energy Crops

    SciTech Connect (OSTI)

    Green, Pamela J.

    2015-08-11

    MicroRNAs (miRNAs) contribute to the control of numerous biological processes through the regulation of specific target mRNAs. Although the identities of these targets are essential to elucidate miRNA function, the targets are much more difficult to identify than the small RNAs themselves. Before this work, we pioneered the genome-wide identification of the targets of Arabidopsis miRNAs using an approach called PARE (German et al., Nature Biotech. 2008; Nature Protocols, 2009). Under this project, we applied PARE to Brachypodium distachyon (Brachypodium), a model plant in the Poaceae family, which includes the major food grain and bioenergy crops. Through in-depth global analysis and examination of specific examples, this research greatly expanded our knowledge of miRNAs and target RNAs of Brachypodium. New regulation in response to environmental stress or tissue type was found, and many new miRNAs were discovered. More than 260 targets of new and known miRNAs with PARE sequences at the precise sites of miRNA-guided cleavage were identified and characterized. Combining PARE data with the small RNA data also identified the miRNAs responsible for initiating approximately 500 phased loci, including one of the novel miRNAs. PARE analysis also revealed that differentially expressed miRNAs in the same family guide specific target RNA cleavage in a correspondingly tissue-preferential manner. The project included generation of small RNA and PARE resources for bioenergy crops, to facilitate ongoing discovery of conserved miRNA-target RNA regulation. By associating specific miRNA-target RNA pairs with known physiological functions, the research provides insights about gene regulation in different tissues and in response to environmental stress. This, and release of new PARE and small RNA data sets should contribute basic knowledge to enhance breeding and may suggest new strategies for improvement of biomass energy crops.

  15. miR-4295 promotes cell proliferation and invasion in anaplastic thyroid carcinoma via CDKN1A

    SciTech Connect (OSTI)

    Shao, Mingchen; Geng, Yiwei; Lu, Peng; Xi, Ying; Wei, Sidong; Wang, Liuxing; Fan, Qingxia; Ma, Wang

    2015-09-04

    MicroRNAs (miRNAs) play important roles in the pathogenesis of many types of cancers by negatively regulating gene expression at posttranscriptional level. However, the role of microRNAs in anaplastic thyroid carcinoma (ATC), has remained elusive. Here, we identified that miR-4295 promotes ATC cell proliferation by negatively regulates its target gene CDKN1A. In ATC cell lines, CCK-8 proliferation assay indicated that the cell proliferation was promoted by miR-4295, while miR-4295 inhibitor significantly inhibited the cell proliferation. Transwell assay showed that miR-4295 mimics significantly promoted the migration and invasion of ATC cells, whereas miR-4295 inhibitors significantly reduced cell migration and invasion. luciferase assays confirmed that miR-4295 directly bound to the 3'untranslated region of CDKN1A, and western blotting showed that miR-4295 suppressed the expression of CDKN1A at the protein levels. This study indicated that miR-4295 negatively regulates CDKN1A and promotes proliferation and invasion of ATC cell lines. Thus, miR-4295 may represent a potential therapeutic target for ATC intervention. - Highlights: • miR-4295 mimics promote the proliferation and invasion of ATC cells. • miR-4295 inhibitors inhibit the proliferation and invasion of ATC cells. • miR-4295 targets 3′UTR of CDKN1A in ATC cells. • miR-4295 negatively regulates CDKN1A in ATC cells.

  16. Microfluidic Molecular Assay Platform for the Detection of miRNAs...

    Office of Scientific and Technical Information (OSTI)

    Article: Microfluidic Molecular Assay Platform for the Detection of miRNAs, mRNAs, Proteins, and Post-translational Modifications at Single-cell Resolution. Citation Details...

  17. Graphene oxide-silica nanohybrids as fillers for PA6 based nanocomposites

    SciTech Connect (OSTI)

    Maio, A.; Fucarino, R.; Khatibi, R.; Botta, L.; Scaffaro, R.; Rosselli, S.; Bruno, M.

    2014-05-15

    Graphene oxide (GO) was prepared by oxidation of graphite flakes by a mixture of H{sub 2}SO{sub 4}/H{sub 3}PO{sub 4} and KMnO{sub 4} based on Marcano's method. Two different masterbatches containing GO (33.3%) and polyamide-6 (PA6) (66.7%) were prepared both via solvent casting in formic acid and by melt mixing in a mini-extruder (Haake). The two masterbatches were then used to prepare PA6-based nanocomposites with a content of 2% in GO. For comparison, a nanocomposite by direct mixing of PA6 and GO (2%) and PA6/graphite nanocomposites were prepared, too. The oxidation of graphite into GO was assessed by X-ray diffraction (XRD), Micro-Raman spectroscopy, scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS) analyses. All these techniques demonstrated the effectiveness of the graphite modification, since the results put into evidence that, after the acid treatment, interlayer distance, oxygen content and defects increased. SEM micrographs carried out on the nanocomposites, showed GO layers totally surrounded by polyamide-6, this feature is likely due to the strong interaction between the hydrophilic moieties located both on GO and on PA6. On the contrary, no interactions were observed when graphite was used as filler. Mechanical characterization, carried out by tensile and dynamic-mechanical tests, marked an improvement of the mechanical properties observed. Photoluminescence and EPR measurements were carried out onto nanoparticles and nanocomposites to study the nature of the interactions and to assess the possibility to use this class of materials as semiconductors or optical sensors.

  18. Groundwater protection for the NuMI project

    SciTech Connect (OSTI)

    Wehmann, A.; Smart, W.; Menary, S.; Hylen, J.; Childress, S.

    1997-10-01

    The physics requirements for the long base line neutrino oscillation experiment MINOS dictate that the NuMI beamline be located in the aquifer at Fermilab. A methodology is described for calculating the level of radioactivation of groundwater caused by operation of this beamline. A conceptual shielding design for the 750 meter long decay pipe is investigated which would reduce radioactivation of the groundwater to below government standards. More economical shielding designs to meet these requirements are being explored. Also, information on local geology, hydrogeology, government standards, and a glossary have been included.

  19. miR-129 suppresses tumor cell growth and invasion by targeting PAK5 in hepatocellular carcinoma

    SciTech Connect (OSTI)

    Zhai, Jian; Qu, Shuping; Li, Xiaowei; Zhong, Jiaming; Chen, Xiaoxia; Qu, Zengqiang; Wu, Dong

    2015-08-14

    Emerging evidence suggests that microRNAs (miRNAs) play important roles in regulating HCC development and progression; however, the mechanisms by which their specific functions and mechanisms remained to be further explored. miR-129 has been reported in gastric cancers, lung cancer and colon cancer. In this study, we disclosed a new tumor suppresser function of miR-129 in HCC. We also found the downregulation of miR-129 occurred in nearly 3/4 of the tumors examined (56/76) compared with adjacent nontumorous tissues, which was more importantly, correlated to the advanced stage and vascular invasion. We then demonstrated that miR-129 overexpression attenuated HCC cells proliferation and invasion, inducing apoptosis in vitro. Moreover, we used miR-129 antagonist and found that anti-miR-129 promoted HCC cells malignant phenotypes. Mechanistically, our further investigations revealed that miR-129 suppressed cell proliferation and invasion by targeting the 3’-untranslated region of PAK5, as well as miR-129 silencing up-regulated PAK5 expression. Moreover, miR-129 expression was inversely correlated with PAK5 expression in 76 cases of HCC samples. RNA interference of PAK5 attenuated anti-miR-129 mediated cell proliferation and invasion in HCC cells. Taken together, these results demonstrated that miR-129 suppressed tumorigenesis and progression by directly targeting PAK5, defining miR-129 as a potential treatment target for HCC. - Highlights: • Decreased of miR-129 is found in HCC and associated with advanced stage and metastasis. • miR-129 suppresses proliferation and invasion of HCC cells. • miR-129 directly targets the 3′ UTR of PAK5 and diminishes PAK5 expression. • PAK5 is involved in miR-129 mediated suppression functions.

  20. MiR-153 inhibits migration and invasion of human non-small-cell lung cancer by targeting ADAM19

    SciTech Connect (OSTI)

    Shan, Nianxi; Shen, Liangfang; Wang, Jun; He, Dan; Duan, Chaojun

    2015-01-02

    Highlights: • Decreased miR-153 and up-regulated ADAM19 are correlated with NSCLC pathology. • MiR-153 inhibits the proliferation and migration and invasion of NSCLC cells in vitro. • ADAM19 is a direct target of miR-153. • ADAM19 is involved in miR-153-suppressed migration and invasion of NSCLC cells. - Abstract: MiR-153 was reported to be dysregulated in some human cancers. However, the function and mechanism of miR-153 in lung cancer cells remains unknown. In this study, we investigated the role of miR-153 in human non-small-cell lung cancer (NSCLC). Using qRT-PCR, we demonstrated that miR-153 was significantly decreased in clinical NSCLC tissues and cell lines, and downregulation of miR-153 was significantly correlated with lymph node status. We further found that ectopic expression of miR-153 significantly inhibited the proliferation and migration and invasion of NSCLC cells in vitro, suggesting that miR-153 may be a novel tumor suppressor in NSCLC. Further integrated analysis revealed that ADAM19 is as a direct and functional target of miR-153. Luciferase reporter assay demonstrated that miR-153 directly targeted 3′UTR of ADAM19, and correlation analysis revealed an inverse correlation between miR-153 and ADAM19 mRNA levels in clinical NSCLC tissues. Knockdown of ADAM19 inhibited migration and invasion of NSCLC cells which was similar with effects of overexpression of miR-153, while overexpression of ADAM19 attenuated the function of miR-153 in NSCLC cells. Taken together, our results highlight the significance of miR-153 and ADAM19 in the development and progression of NSCLC.

  1. Transcriptional regulation of miR-146b by C/EBPβ LAP2 in esophageal cancer cells

    SciTech Connect (OSTI)

    Li, Junxia; Shan, Fabo; Xiong, Gang; Wang, Ju-Ming; Wang, Wen-Lin; Xu, Xueqing; Bai, Yun

    2014-03-28

    Highlights: • MiR-146b promotes esophageal cancer cell proliferation. • MiR-146b inhibits esophageal cancer cell apoptosis. • C/EBPβ directly binds to miR-146b promoter conserved region. • MiR-146b is up-regulated by C/EBPβ LAP2 transcriptional activation. - Abstract: Recent clinical study indicated that up-regulation of miR-146b was associated with poor overall survival of patients in esophageal squamous cell carcinoma. However, the underlying mechanism of miR-146b dysregulation remains to be explored. Here we report that miR-146b promotes cell proliferation and inhibits cell apoptosis in esophageal cancer cell lines. Mechanismly, two C/EBPβ binding motifs are located in the miR-146b promoter conserved region. Among the three isoforms of C/EBPβ, C/EBPβ LAP2 positively regulated miR-146b expression and increases miR-146b levels in a dose-dependent manner through transcription activation of miR-146b gene. Together, these results suggest a miR-146b regulatory mechanism involving C/EBPβ, which may contribute to the up-regulation of miR-146b in esophageal squamous cell carcinoma.

  2. Project Plan 7930 Cell G PaR Remote Handling System Replacement

    SciTech Connect (OSTI)

    Kinney, Kathryn A

    2009-10-01

    For over 40 years the US Department of Energy (DOE) and its predecessors have made Californium-252 ({sup 252}Cf) available for a wide range of industries including medical, nuclear fuels, mining, military and national security. The Radiochemical Engineering Development Center (REDC) located within the Oak Ridge National Laboratory (ORNL) processes irradiated production targets from the High Flux Isotope Reactor (HFIR). Operations in Building 7930, Cell G provide over 70% of the world's demand for {sup 252}Cf. Building 7930 was constructed and equipped in the mid-1960s. Current operations for {sup 252}Cf processing in Building 7930, Cell G require use of through-the-wall manipulators and the PaR Remote Handling System. Maintenance and repairs for the manipulators is readily accomplished by removal of the manipulator and relocation to a repair shop where hands-on work can be performed in glove boxes. Contamination inside cell G does not currently allow manned entry and no provisions were created for a maintenance area inside the cell. There has been no maintenance of the PaR system or upgrades, leaving operations vulnerable should the system have a catastrophic failure. The Cell G PaR system is currently being operated in a run to failure mode. As the manipulator is now 40+ years old there is significant risk in this method of operation. In 2006 an assessment was completed that resulted in recommendations for replacing the manipulator operator control and power centers which are used to control and power the PaR manipulator in Cell G. In mid-2008 the chain for the bridge drive failed and subsequent examinations indicated several damaged links (see Figure 1). To continue operations the PaR manipulator arm is being used to push and pull the bridge as a workaround. A retrieval tool was fabricated, tested and staged inside Cell G that will allow positioning of the bridge and manipulator arm for removal from the cell should the PaR system completely fail. A fully

  3. miR-30a suppresses breast cancer cell proliferation and migration by targeting Eya2

    SciTech Connect (OSTI)

    Fu, Jing; Xu, Xiaojie; Kang, Lei; Zhou, Liying; Wang, Shibin; Lu, Juming; Cheng, Long; Fan, Zhongyi; Yuan, Bin; Tian, Peirong; Zheng, Xiaofei; Yu, Chengze; Ye, Qinong; Lv, Zhaohui

    2014-03-07

    Highlights: • miR-30a represses Eya2 expression by binding to the 3′-untranslated region of Eya2. • The miR-30a/EYA2 axis regulates breast cancer cell proliferation and migration. • The miR-30a/EYA2 axis modulates G1/S cell cycle progression. • The miR-30a/EYA2 axis is dysregulated in breast cancer patients. - Abstract: Eye absent (Eya) proteins are involved in cell fate determination in a broad spectrum of cells and tissues. Aberrant expression of Eya2 has been documented in a variety of cancers and correlates with clinical outcome. However, whether microRNAs (miRNAs) can regulate Eya2 expression remains unknown. Here, we show that miR-30a represses Eya2 expression by binding to the 3′-untranslated region of Eya2. Overexpression of Eya2 in miR-30a-transfected breast cancer cells effectively rescued the inhibition of cell proliferation and migration caused by miR-30a. Knockdown of Eya2 by small-interfering RNA (siRNA) in breast cancer cells mimicked the effect induced by miR-30a and abolished the ability of miR-30a to regulate breast cancer cell proliferation and migration. The miR-30a/Eya2 axis could regulate G1/S cell cycle progression, accompanied by the modulation of expression of cell cycle-related proteins, including cyclin A, cyclin D1, cyclin E, and c-Myc. Moreover, miR-30a expression was downregulated in breast cancer patients, and negatively correlated with Eya2, which was upregulated in breast cancer patients. These data suggest that the miR-30a/Eya2 axis may play an important role in breast cancer development and progression and that miR-30a activation or Eya2 inhibition may be a useful strategy for cancer treatment.

  4. Albany, OR * Anchorage, AK * Morgantown, WV * Pittsburgh, PA * Sugar Land, TX

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Training Center CONTACTS Traci Rodosta Carbon Storage Technology Manager National Energy Technology Laboratory 3610 Collins Ferry Road PO Box 880 Morgantown, WV 26507 304-285-1345 traci.rodosta@netl.doe.gov Andrea Dunn Project Manager National Energy Technology Laboratory 626 Cochrans Mill Road P.O. Box 10940 Pittsburgh, PA 15236 412-386-7594 andrea.dunn@netl.doe.gov Hilary Olson Project Director/Principal Investigator University of Texas at Austin 1 University Station, C0300 Austin, TX

  5. Albany, OR * Anchorage, AK * Morgantown, WV * Pittsburgh, PA * Sugar Land, TX

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    gov William Aljoe Project Manager National Energy Technology Laboratory 626 Cochrans Mill Road P.O. Box 10940 Pittsburgh, PA 15236-0940 412-386-6569 william.aljoe@netl.doe.gov Lee Spangler Principal Investigator Montana State University P.O. Box 173905 Bozeman, MT 59717-3905 406-994-4399 spangler@montana.edu PARTNERS Altamont Oil & Gas Inc. Barnard College Columbia University Idaho National Laboratory Lawrence Berkeley National Laboratory Los Alamos National Laboratory Schlumberger Carbon

  6. miR-92a is upregulated in cervical cancer and promotes cell proliferation and invasion by targeting FBXW7

    SciTech Connect (OSTI)

    Zhou, Chuanyi; Shen, Liangfang; Mao, Lei; Wang, Bing; Li, Yang; Yu, Huizhi

    2015-02-27

    MicroRNAs (miRNAs) are involved in the cervical carcinogenesis and progression. In this study, we investigated the role of miR-92a in progression and invasion of cervical cancer. MiR-92a was significantly upregulated in cervical cancer tissues and cell lines. Overexpression of miR-92a led to remarkably enhanced proliferation by promoting cell cycle transition from G1 to S phase and significantly enhanced invasion of cervical cancer cells, while its knockdown significantly reversed these cellular events. Bioinformatics analysis suggested F-box and WD repeat domain-containing 7 (FBXW7) as a novel target of miR-92a, and miR-92a suppressed the expression level of FBXW7 mRNA by direct binding to its 3′-untranslated region (3′UTR). Expression of miR-92a was negatively correlated with FBXW7 in cervical cancer tissues. Furthermore, Silencing of FBXW7 counteracted the effects of miR-92a suppression, while its overexpression reversed oncogenic effects of miR-92a. Together, these findings indicate that miR-92a acts as an onco-miRNA and may contribute to the progression and invasion of cervical cancer, suggesting miR-92a as a potential novel diagnostic and therapeutic target of cervical cancer. - Highlights: • miR-92a is elevated in cervical cancer tissues and cell lines. • miR-92a promotes cervical cancer cell proliferation, cell cycle transition from G1 to S phase and invasion. • FBXW7 is a direct target of miR-92a. • FBXW7 counteracts the oncogenic effects of miR-92a on cervical cancer cells.

  7. miR-182 targets CHL1 and controls tumor growth and invasion in papillary thyroid carcinoma

    SciTech Connect (OSTI)

    Zhu, Hongling; Fang, Jin; Zhang, Jichen; Zhao, Zefei; Liu, Lianyong; Wang, Jingnan; Xi, Qian; Gu, Mingjun

    2014-07-18

    Highlights: miR-182 and CHL1 expression patterns are negatively correlated. CHL1 is a direct target of miR-182 in PTC cells. miR-182 suppression inhibits PTC cell growth and invasion. CHL1 is involved in miR-182-mediated cell behavior. - Abstract: In this study, we investigated the role and underlying mechanism of action of miR-182 in papillary thyroid carcinoma (PTC). Bioinformatics analysis revealed close homolog of LI (CHL1) as a potential target of miR-182. Upregulation of miR-182 was significantly correlated with CHL1 downregulation in human PTC tissues and cell lines. miR-182 suppressed the expression of CHL1 mRNA through direct targeting of the 3?-untranslated region (3?-UTR). Downregulation of miR-182 suppressed growth and invasion of PTC cells. Silencing of CHL1 counteracted the effects of miR-182 suppression, while its overexpression mimicked these effects. Our data collectively indicate that miR-182 in PTC promotes cell proliferation and invasion through direct suppression of CHL1, supporting the potential utility of miR-182 inhibition as a novel therapeutic strategy against PTC.

  8. Non-canonical microRNAs miR-320 and miR-702 promote proliferation in Dgcr8-deficient embryonic stem cells

    SciTech Connect (OSTI)

    Kim, Byeong-Moo; Choi, Michael Y.

    2012-09-21

    Highlights: Black-Right-Pointing-Pointer Embryonic stem cells (ESCs) lacking non-canonical miRNAs proliferate slower. Black-Right-Pointing-Pointer miR-320 and miR-702 are two non-canonical miRNAs expressed in ESCs. Black-Right-Pointing-Pointer miR-320 and miR-702 promote proliferation of Dgcr8-deficient ESCs. Black-Right-Pointing-Pointer miR-320 targets p57 and helps to release Dgcr8-deficient ESCs from G1 arrest. Black-Right-Pointing-Pointer miR-702 targets p21 and helps to release Dgcr8-deficient ESCs from G1 arrest. -- Abstract: MicroRNAs are known to contribute significantly to stem cell phenotype by post-transcriptionally regulating gene expression. Most of our knowledge of microRNAs comes from the study of canonical microRNAs that require two sequential cleavages by the Drosha/Dgcr8 heterodimer and Dicer to generate mature products. In contrast, non-canonical microRNAs bypass the cleavage by the Drosha/Dgcr8 heterodimer within the nucleus but still require cytoplasmic cleavage by Dicer. The function of non-canonical microRNAs in embryonic stem cells (ESCs) remains obscure. It has been hypothesized that non-canonical microRNAs have important roles in ESCs based upon the phenotypes of ESC lines that lack these specific classes of microRNAs; Dicer-deficient ESCs lacking both canonical and non-canonical microRNAs have much more severe proliferation defect than Dgcr8-deficient ESCs lacking only canonical microRNAs. Using these cell lines, we identified two non-canonical microRNAs, miR-320 and miR-702, that promote proliferation of Dgcr8-deficient ESCs by releasing them from G1 arrest. This is accomplished by targeting the 3 Prime -untranslated regions of the cell cycle inhibitors p57 and p21 and thereby inhibiting their expression. This is the first report of the crucial role of non-canonical microRNAs in ESCs.

  9. NuMI proton kicker extraction magnet termination resistor system

    SciTech Connect (OSTI)

    Reeves, S.R.; Jensen, C.C.; /Fermilab

    2005-05-01

    The temperature stability of the kicker magnet termination resistor assembly directly affects the field flatness and amplitude stability. Comprehensive thermal enhancements were made to the existing Main Injector resistor assembly design to satisfy NuMI performance specifications. Additionally, a fluid-processing system utilizing Fluorinert{reg_sign} FC-77 high-voltage dielectric was built to precisely control the setpoint temperature of the resistor assembly from 70 to 120F, required to maintain constant resistance during changing operational modes. The Fluorinert{reg_sign} must be continually processed to remove hazardous breakdown products caused by radiation exposure to prevent chemical attack of system components. Design details of the termination resistor assembly and Fluorinert{reg_sign} processing system are described. Early performance results will be presented.

  10. Downregulation of miRNA-30c and miR-203a is associated with hepatitis C virus core protein-induced epithelial–mesenchymal transition in normal hepatocytes and hepatocellular carcinoma cells

    SciTech Connect (OSTI)

    Liu, Dongjing; Wu, Jilin; Liu, Meizhou; Yin, Hui; He, Jiantai; Zhang, Bo

    2015-09-04

    Hepatitis C virus (HCV) Core protein has been demonstrated to induce epithelial–mesenchymal transition (EMT) and is associated with cancer progression of hepatocellular carcinoma (HCC). However, how the Core protein regulates EMT is still unclear. In this study, HCV Core protein was overexpressed by an adenovirus. The protein levels of EMT markers were measured by Western blot. The xenograft animal model was established by inoculation of HepG2 cells. Results showed that ectopic expression of HCV core protein induced EMT in L02 hepatocytes and HepG2 tumor cells by upregulating vimentin, Sanl1, and Snal2 expression and downregulating E-cadherin expression. Moreover, Core protein downregulated miR-30c and miR-203a levels in L02 and HepG2 cells, but artificial expression of miR-30c and miR-203a reversed Core protein-induced EMT. Further analysis showed that ectopic expression of HCV core protein stimulated cell proliferation, inhibited apoptosis, and increased cell migration, whereas artificial expression of miR-30c and miR-203a significantly reversed the role of Core protein in these cell functions in L02 and HepG2 cells. In the HepG2 xenograft tumor models, artificial expression of miR-30c and miR-203a inhibited EMT and tumor growth. Moreover, L02 cells overexpressing Core protein can form tumors in nude mice. In HCC patients, HCV infection significantly shortened patients' survival time, and loss of miR-30c and miR-203 expression correlated with poor survival. In conclusion, HCV core protein downregulates miR-30c and miR-203a expression, which results in activation of EMT in normal hepatocytes and HCC tumor cells. The Core protein-activated-EMT is involved in the carcinogenesis and progression of HCC. Loss of miR-30c and miR-203a expression is a marker for the poor prognosis of HCC. - Highlights: • HCV core protein downregulates miR-30c and miR-203a expression. • Downregulation of miR-30c and miR-203a activates EMT. • Activated-EMT is involved in the