National Library of Energy BETA

Sample records for mi elevation profile

  1. Repression of miR-17-5p with elevated expression of E2F-1 and c-MYC in non-metastatic hepatocellular carcinoma and enhancement of cell growth upon reversing this expression pattern

    SciTech Connect (OSTI)

    El Tayebi, H.M.; Omar, K.; Hegy, S.; El Maghrabi, M.; El Brolosy, M. [The Molecular Pathology Research Group, Department of Pharmacology and Toxicology, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo (Egypt)] [The Molecular Pathology Research Group, Department of Pharmacology and Toxicology, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo (Egypt); Hosny, K.A. [Department of General Surgery, Faculty of Medicine, Cairo University, Cairo (Egypt)] [Department of General Surgery, Faculty of Medicine, Cairo University, Cairo (Egypt); Esmat, G. [Department of Endemic Medicine and Hepatology, Cairo University, Cairo (Egypt)] [Department of Endemic Medicine and Hepatology, Cairo University, Cairo (Egypt); Abdelaziz, A.I., E-mail: ahmed.abdel-aziz@guc.edu.eg [The Molecular Pathology Research Group, Department of Pharmacology and Toxicology, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo (Egypt)

    2013-05-10

    Highlights: •The oncogenic miR-17-5p is downregulated in non-metastatic hepatocellular carcinoma patients. •E2F-1 and c-MYC transcripts are upregulated in non-metastatic HCC patients. •miR-17-5p forced overexpression inhibited E2F-1 and c-MYC expression in HuH-7 cells. •miR-17-5p mimicking increased HuH-7 cell growth, proliferation, migration and colony formation. •miR-17-5p is responsible for HCC progression among the c-MYC/E2F-1/miR-17-5p triad members. -- Abstract: E2F-1, c-MYC, and miR-17-5p is a triad of two regulatory loops: a negative and a positive loop, where c-MYC induces the expression of E2F-1 that induces the expression of miR-17-5p which in turn reverses the expression of E2F-1 to close the loop. In this study, we investigated this triad for the first time in hepatocellular carcinoma (HCC), where miR-17-5p showed a significant down-regulation in 23 non-metastatic HCC biopsies compared to 10 healthy tissues; however, E2F-1 and c-MYC transcripts were markedly elevated. Forced over-expression of miR-17-5p in HuH-7 cells resulted in enhanced cell proliferation, growth, migration and clonogenicity with concomitant inhibition of E2F-1 and c-MYC transcripts expressions, while antagomirs of miR-17-5p reversed these events. In conclusion, this study revealed a unique pattern of expression for miR-17-5p in non-metastatic HCC patients in contrast to metastatic HCC patients. In addition we show that miR-17-5p is the key player among the triad that tumor growth and spread.

  2. NONPROFIT ORG DETROIT, MI

    E-Print Network [OSTI]

    Berdichevsky, Victor

    NONPROFIT ORG US POSTAGE PAID DETROIT, MI PERMIT NO 3844 College of Engineering Wayne State University 5050 Anthony Wayne Drive Room 1153 · Detroit, MI 48202 Phone (313) 577-3780 · Fax (313) 577, Wayne State University 5050 Anthony Wayne Drive Detroit, MI 48202 My first assignment for Ex

  3. Real-time sub-<mi>Å>ngstrom...

    Office of Scientific and Technical Information (OSTI)

    Real-time sub-<mi>>ngstrom imaging of reversible and irreversible conformations in rhodium catalysts and graphene Kisielowski, Christian; Wang,...

  4. Package `MiST' July 2, 2014

    E-Print Network [OSTI]

    Brent, Roger

    Package `MiST' July 2, 2014 Type Package Title Mixed effects Score Test for continuous outcomes topics documented: MiST-package 10 1 #12;2 linear.test MiST-package Mixed effects Score Test Description Test for association between

  5. miR-196a targets netrin 4 and regulates cell proliferation and migration of cervical cancer cells

    SciTech Connect (OSTI)

    Zhang, Jie; Zheng, Fangxia; Yu, Gang; Yin, Yanhua; Lu, Qingyang

    2013-11-01

    Highlights: •miR-196a was overexpressed in cervical cancer tissue compared to normal tissue. •miR-196a expression elevated proliferation and migration of cervical cancer cells. •miR-196a inhibited NTN4 expression by binding 3?-UTR region of NTN4 mRNA. •NTN4 inversely correlated with miR-196a expression in cervical tissue and cell line. •NTN4 expression was low in cervical cancer tissue compared to normal tissue. -- Abstract: Recent research has uncovered tumor-suppressive and oncogenic potential of miR-196a in various tumors. However, the expression and mechanism of its function in cervical cancer remains unclear. In this study, we assess relative expression of miR-196a in cervical premalignant lesions, cervical cancer tissues, and four cancer cell lines using quantitative real-time PCR. CaSki and HeLa cells were treated with miR-196a inhibitors, mimics, or pCDNA/miR-196a to investigate the role of miR-196a in cancer cell proliferation and migration. We demonstrated that miR-196a was overexpressed in cervical intraepithelial neoplasia 2–3 and cervical cancer tissue. Moreover, its expression contributes to the proliferation and migration of cervical cancer cells, whereas inhibiting its expression led to a reduction in proliferation and migration. Five candidate targets of miR-196a chosen by computational prediction and Cervical Cancer Gene Database search were measured for their mRNA in both miR-196a-overexpressing and -depleted cancer cells. Only netrin 4 (NTN4) expression displayed an inverse association with miR-196a. Fluorescent reporter assays revealed that miR-196a inhibited NTN4 expression by targeting one binding site in the 3?-untranslated region (3?-UTR) of NTN4 mRNA. Furthermore, qPCR and Western blot assays verified NTN4 expression was downregulated in cervical cancer tissues compared to normal controls, and in vivo mRNA level of NTN4 inversely correlated with miR-196a expression. In summary, our findings provide new insights about the functional role of miR-196a in cervical carcinogenesis and suggested a potential use of miR-196a for clinical diagnosis and as a therapeutic target.

  6. miRNAs in brain development

    SciTech Connect (OSTI)

    Petri, Rebecca; Malmevik, Josephine; Fasching, Liana; Åkerblom, Malin; Jakobsson, Johan

    2014-02-01

    MicroRNAs (miRNAs) are small, non-coding RNAs that negatively regulate gene expression at the post-transcriptional level. In the brain, a large number of miRNAs are expressed and there is a growing body of evidence demonstrating that miRNAs are essential for brain development and neuronal function. Conditional knockout studies of the core components in the miRNA biogenesis pathway, such as Dicer and DGCR8, have demonstrated a crucial role for miRNAs during the development of the central nervous system. Furthermore, mice deleted for specific miRNAs and miRNA-clusters demonstrate diverse functional roles for different miRNAs during the development of different brain structures. miRNAs have been proposed to regulate cellular functions such as differentiation, proliferation and fate-determination of neural progenitors. In this review we summarise the findings from recent studies that highlight the importance of miRNAs in brain development with a focus on the mouse model. We also discuss the technical limitations of current miRNA studies that still limit our understanding of this family of non-coding RNAs and propose the use of novel and refined technologies that are needed in order to fully determine the impact of specific miRNAs in brain development. - Highlights: • miRNAs are essential for brain development and neuronal function. • KO of Dicer is embryonically lethal. • Conditional Dicer KO results in defective proliferation or increased apoptosis. • KO of individual miRNAs or miRNA families is necessary to determine function.

  7. cis-and trans-Regulation of miR163 and Target Genes Confers Natural Variation of Secondary Metabolites in Two Arabidopsis

    E-Print Network [OSTI]

    Tholl, Dorothea

    involved in secondary metabolite biosynthetic pathways that are inducible by a fungal elicitor, alamethicin and secondary metabolite profiles. We suggest that cis- and trans-regulation of miRNA and other genes providescis- and trans-Regulation of miR163 and Target Genes Confers Natural Variation of Secondary

  8. MI high power operation and future plans

    SciTech Connect (OSTI)

    Kourbanis, Ioanis; /Fermilab

    2008-09-01

    Fermilab's Main Injector on acceleration cycles to 120 GeV has been running a mixed mode operation delivering beam to both the antiproton source for pbar production and to the NuMI[1] target for neutrino production since 2005. On January 2008 the slip stacking process used to increase the beam to the pbar target was expanded to include the beam to the NuMI target increasing both the beam intensity and power. The current high power MI operation will be described along with the near future plans.

  9. The NuMI Neutrino Beam

    E-Print Network [OSTI]

    P. Adamson; K. Anderson; M. Andrews; R. Andrews; I. Anghel; D. Augustine; A. Aurisano; S. Avvakumov; D. S. Ayres; B. Baller; B. Barish; G. Barr; W. L. Barrett; R. H. Bernstein; J. Biggs; M. Bishai; A. Blake; V. Bocean; G. J. Bock; D. J. Boehnlein; D. Bogert; K. Bourkland; S. V. Cao; C. M. Castromonte; S. Childress; B. C. Choudhary; J. A. B. Coelho; J. H. Cobb; L. Corwin; D. Crane; J. P. Cravens; D. Cronin-Hennessy; R. J. Ducar; J. K. de Jong; A. V. Devan; N. E. Devenish; M. V. Diwan; A. R. Erwin; C. O. Escobar; J. J. Evans; E. Falk; G. J. Feldman; T. H. Fields; R. Ford; M. V. Frohne; H. R. Gallagher; V. Garkusha; R. A. Gomes; M. C. Goodman; P. Gouffon; N. Graf; R. Gran; N. Grossman; K. Grzelak; A. Habig; S. R. Hahn; D. Harding; D. Harris; P. G. Harris; J. Hartnell; R. Hatcher; S. Hays; K. Heller; A. Holin; J. Huang; J. Hylen; A. Ibrahim; D. Indurthy; G. M. Irwin; Z. Isvan; D. E. Jaffe; C. James; D. Jensen; J. Johnstone; T. Kafka; S. M. S. Kasahara; G. Koizumi; S. Kopp; M. Kordosky; A. Kreymer; K. Lang; C. Laughton; G. Lefeuvre; J. Ling; P. J. Litchfield; L. Loiacono; P. Lucas; W. A. Mann; A. Marchionni; M. L. Marshak; N. Mayer; C. McGivern; M. M. Medeiros; R. Mehdiyev; J. R. Meier; M. D. Messier; D. G. Michael; R. H. Milburn; J. L. Miller; W. H. Miller; S. R. Mishra; S. Moed Sher; C. D. Moore; J. Morfin; L. Mualem; S. Mufson; S. Murgia; M. Murtagh; J. Musser; D. Naples; J. K. Nelson; H. B. Newman; R. J. Nichol; J. A. Nowak; J. O Connor; W. P. Oliver; M. Olsen; M. Orchanian; S. Osprey; R. B. Pahlka; J. Paley; A. Para; R. B. Patterson; T. Patzak; Z. Pavlovic; G. Pawloski; A. Perch; E. A. Peterson; D. A. Petyt; M. M. Pfutzner; S. Phan-Budd; R. K. Plunkett; N. Poonthottathil; P. Prieto; D. Pushka; X. Qiu; A. Radovic; R. A. Rameika; J. Ratchford; B. Rebel; R. Reilly; C. Rosenfeld; H. A. Rubin; K. Ruddick; M. C. Sanchez; N. Saoulidou; L. Sauer; J. Schneps; D. Schoo; A. Schreckenberger; P. Schreiner; P. Shanahan; R. Sharma; W. Smart; C. Smith; A. Sousa; A. Stefanik; N. Tagg; R. L. Talaga; G. Tassotto; J. Thomas; J. Thompson; M. A. Thomson; X. Tian; A. Timmons; D. Tinsley; S. C. Tognini; R. Toner; D. Torretta; I. Trostin; G. Tzanakos; J. Urheim; P. Vahle; K. Vaziri; E. Villegas; B. Viren; G. Vogel; R. C. Webber; A. Weber; R. C. Webb; A. Wehmann; C. White; L. Whitehead; L. H. Whitehead; S. G. Wojcicki; M. L. Wong-Squires; T. Yang; F. X. Yumiceva; V. Zarucheisky; R. Zwaska

    2015-07-29

    This paper describes the hardware and operations of the Neutrinos at the Main Injector (NuMI) beam at Fermilab. It elaborates on the design considerations for the beam as a whole and for individual elements. The most important design details of individual components are described. Beam monitoring systems and procedures, including the tuning and alignment of the beam and NuMI long-term performance, are also discussed.

  10. The NuMI Neutrino Beam

    E-Print Network [OSTI]

    Adamson, P; Andrews, M; Andrews, R; Anghel, I; Augustine, D; Aurisano, A; Avvakumov, S; Ayres, D S; Baller, B; Barish, B; Barr, G; Barrett, W L; Bernstein, R H; Biggs, J; Bishai, M; Blake, A; Bocean, V; Bock, G J; Boehnlein, D J; Bogert, D; Bourkland, K; Cao, S V; Castromonte, C M; Childress, S; Choudhary, B C; Coelho, J A B; Cobb, J H; Corwin, L; Crane, D; Cravens, J P; Cronin-Hennessy, D; Ducar, R J; de Jong, J K; Devan, A V; Devenish, N E; Diwan, M V; Erwin, A R; Escobar, C O; Evans, J J; Falk, E; Feldman, G J; Fields, T H; Ford, R; Frohne, M V; Gallagher, H R; Garkusha, V; Gomes, R A; Goodman, M C; Gouffon, P; Graf, N; Gran, R; Grossman, N; Grzelak, K; Habig, A; Hahn, S R; Harding, D; Harris, D; Harris, P G; Hartnell, J; Hatcher, R; Hays, S; Heller, K; Holin, A; Huang, J; Hylen, J; Ibrahim, A; Indurthy, D; Irwin, G M; Isvan, Z; Jaffe, D E; James, C; Jensen, D; Johnstone, J; Kafka, T; Kasahara, S M S; Koizumi, G; Kopp, S; Kordosky, M; Kreymer, A; Lang, K; Laughton, C; Lefeuvre, G; Ling, J; Litchfield, P J; Loiacono, L; Lucas, P; Mann, W A; Marchionni, A; Marshak, M L; Mayer, N; McGivern, C; Medeiros, M M; Mehdiyev, R; Meier, J R; Messier, M D; Michael, D G; Milburn, R H; Miller, J L; Miller, W H; Mishra, S R; Sher, S Moed; Moore, C D; Morfin, J; Mualem, L; Mufson, S; Murgia, S; Murtagh, M; Musser, J; Naples, D; Nelson, J K; Newman, H B; Nichol, R J; Nowak, J A; Connor, J O; Oliver, W P; Olsen, M; Orchanian, M; Osprey, S; Pahlka, R B; Paley, J; Para, A; Patterson, R B; Patzak, T; Pavlovic, Z; Pawloski, G; Perch, A; Peterson, E A; Petyt, D A; Pfutzner, M; Phan-Budd, S; Plunkett, R K; Poonthottathil, N; Prieto, P; Pushka, D; Qiu, X; Radovic, A; Rameika, R A; Ratchford, J; Rebel, B; Reilly, R; Rosenfeld, C; Rubin, H A; Ruddick, K; Sanchez, M C; Saoulidou, N; Sauer, L; Schneps, J; Schoo, D; Schreckenberger, A; Schreiner, P; Shanahan, P; Sharma, R; Smart, W; Smith, C; Sousa, A; Stefanik, A; Tagg, N; Talaga, R L; Tassotto, G; Thomas, J; Thompson, J; Thomson, M A; Tian, X; Timmons, A; Tinsley, D; Tognini, S C; Toner, R; Torretta, D; Trostin, I; Tzanakos, G; Urheim, J; Vahle, P; Vaziri, K; Villegas, E; Viren, B; Vogel, G; Webber, R C; Weber, A; Webb, R C; Wehmann, A; White, C; Whitehead, L; Whitehead, L H; Wojcicki, S G; Wong-Squires, M L; Yang, T; Yumiceva, F X; Zarucheisky, V; Zwaska, R

    2015-01-01

    This paper describes the hardware and operations of the Neutrinos at the Main Injector (NuMI) beam at Fermilab. It elaborates on the design considerations for the beam as a whole and for individual elements. The most important design details of individual components are described. Beam monitoring systems and procedures, including the tuning and alignment of the beam and NuMI long-term performance, are also discussed.

  11. The NuMI Neutrino Beam

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Adamson, P.; Anderson, K.; Andrews, M.; Andrews, R.; Anghel, I.; Augustine, D.; Aurisano, A.; Avvakumov, S.; Ayres, D. S.; Baller, B.; et al

    2015-10-20

    Our paper describes the hardware and operations of the Neutrinos at the Main Injector (NuMI) beam at Fermilab. It elaborates on the design considerations for the beam as a whole and for individual elements. The most important part of our design details pertaining to individual components is described. Beam monitoring systems and procedures, including the tuning and alignment of the beam and NuMI long-term performance, are also discussed.

  12. Elevance Pilot-Scale Biorefinery

    Broader source: Energy.gov [DOE]

    The Elevance biorefinery uses catalyst technology to produce fuels and chemicals from renewable, natural oils.

  13. Targeting miR-21 enhances the sensitivity of human colon cancer HT-29 cells to chemoradiotherapy in vitro

    SciTech Connect (OSTI)

    Deng, Jun; Lei, Wan; Fu, Jian-Chun; Zhang, Ling; Li, Jun-He; Xiong, Jian-Ping

    2014-01-17

    Highlight: •MiR-21 plays a significant role in 5-FU resistance. •This role might be attributed to targeting of hMSH2 as well as TP and DPD via miR-21 targeted hMSH2. •Indirectly targeted TP and DPD to influence 5-FU chemotherapy sensitivity. -- Abstract: 5-Fluorouracil (5-FU) is a classic chemotherapeutic drug that has been widely used for colorectal cancer treatment, but colorectal cancer cells are often resistant to primary or acquired 5-FU therapy. Several studies have shown that miR-21 is significantly elevated in colorectal cancer. This suggests that this miRNA might play a role in this resistance. In this study, we investigated this possibility and the possible mechanism underlying this role. We showed that forced expression of miR-21 significantly inhibited apoptosis, enhanced cell proliferation, invasion, and colony formation ability, promoted G1/S cell cycle transition and increased the resistance of tumor cells to 5-FU and X radiation in HT-29 colon cancer cells. Furthermore, knockdown of miR-21 reversed these effects on HT-29 cells and increased the sensitivity of HT-29/5-FU to 5-FU chemotherapy. Finally, we showed that miR-21 targeted the human mutS homolog2 (hMSH2), and indirectly regulated the expression of thymidine phosphorylase (TP) and dihydropyrimidine dehydrogenase (DPD). These results demonstrate that miR-21 may play an important role in the 5-FU resistance of colon cancer cells.

  14. MI Gap Clearing Kicker Magnet Design Review

    SciTech Connect (OSTI)

    Jensen, Chris; /Fermilab

    2008-10-01

    The kicker system requirements were originally conceived for the NOvA project. NOvA is a neutrino experiment located in Minnesota. To achieve the desired neutrino flux several upgrades are required to the accelerator complex. The Recycler will be used as a proton pre-injector for the Main Injector (MI). As the Recycler is the same size as the MI, it is possible to do a single turn fill ({approx}11 {micro}sec), minimizing the proton injection time in the MI cycle and maximizing the protons on target. The Recycler can then be filled with beam while the MI is ramping to extract beam to the target. To do this requires two new transfer lines. The existing Recycler injection line was designed for 10{pi} pbar beams, not the 20{pi} proton beams we anticipate from the Booster. The existing Recycler extraction line allows for proton injection through the MI, while we want direct injection from the Booster. These two lines will be decommissioned. The new injection line from the MI8 line into the Recycler will start at 848 and end with injection kickers at RR104. The new extraction line in the RR30 straight section will start with a new extraction kicker at RR232 and end with new MI injection kickers at MI308. Finally, to reduce beam loss activation in the enclosure, a new gap clearing kicker will be used to extract uncaptured beam created during the slip stack injection process down the existing dump line. It was suggested that the MI could benefit from this type of system immediately. This led to the early installation of the gap clearing system in the MI, followed by moving the system to Recycler during NOvA. The specifications also changed during this process. Initially the rise and fall time requirements were 38 ns and the field stability was {+-}1%. The 38 ns is based on having a gap of 2 RF buckets between injections. (There are 84 RF buckets that can be filled from the Booster for each injection, but 82 would be filled with beam. MI and Recycler contain 588 RF buckets.) A rough cost/benefit analysis showed that increasing the number of empty buckets to 3 decreased the kicker system cost by {approx}30%. This could be done while not extending the running time since this is only a 1% reduction in protons per pulse, hence the rise and fall time are now 57 ns. Additionally, the {+-}1% tolerance would have required a fast correction kicker while {+-}3% could be achieved without this kicker. The loosened tolerance was based on experience on wide band damping systems in the MI. A higher power wideband damping system is a better use of the resources as it can be used to correct for multiple sources of emittance growth. Finally, with the use of this system for MI instead of Recycler, the required strength grew from 1.2 mrad to 1.7 mrad. The final requirements for this kicker are listed.

  15. Sequence determinants of pri-miRNA processing

    E-Print Network [OSTI]

    Auyeung, Vincent C. (Vincent Churk-man)

    2012-01-01

    MicroRNAs (miRNAs) are short RNAs that regulate many processes in physiology and pathology by guiding the repression of target messenger RNAs. For classification purposes, miRNAs are defined as ~22 nt RNAs that are produced ...

  16. People Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    People Profiles Featured Profile Peter Thelin The art of optics Read More Lisa Burrows Lisa Burrows Jeremy Huckins Jeremy Huckins Ibo Matthews Ibo Matthews Susanna Reyes Susana...

  17. miR-132 and miR-212 are increased in pancreatic cancer and target the retinoblastoma tumor suppressor

    SciTech Connect (OSTI)

    Park, Jong-Kook [College of Pharmacy, Ohio State University, Columbus, OH 43210 (United States)] [College of Pharmacy, Ohio State University, Columbus, OH 43210 (United States); Henry, Jon C. [Department of Surgery, Ohio State University, Columbus, OH 43210 (United States)] [Department of Surgery, Ohio State University, Columbus, OH 43210 (United States); Jiang, Jinmai [College of Pharmacy, Ohio State University, Columbus, OH 43210 (United States)] [College of Pharmacy, Ohio State University, Columbus, OH 43210 (United States); Esau, Christine [Regulus Therapeutics, Carlsbad, CA (United States)] [Regulus Therapeutics, Carlsbad, CA (United States); Gusev, Yuriy [Lombardi Cancer Center, Georgetown University, Washington, DC (United States)] [Lombardi Cancer Center, Georgetown University, Washington, DC (United States); Lerner, Megan R. [Veterans Affairs Medical Center, Oklahoma City, OK (United States)] [Veterans Affairs Medical Center, Oklahoma City, OK (United States); Postier, Russell G. [Department of Surgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK (United States)] [Department of Surgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK (United States); Brackett, Daniel J. [Veterans Affairs Medical Center, Oklahoma City, OK (United States)] [Veterans Affairs Medical Center, Oklahoma City, OK (United States); Schmittgen, Thomas D., E-mail: Schmittgen.2@osu.edu [College of Pharmacy, Ohio State University, Columbus, OH 43210 (United States)

    2011-03-25

    Research highlights: {yields} The expression of miR-132 and miR-212 are significantly increased in pancreatic cancer. {yields} miR-132 and miR-212 target the tumor suppressor pRb, resulting in enhanced proliferation. {yields} miR-132 and miR-212 expression is increased by a {beta}2 adrenergic receptor agonist, suggesting a novel mechanism for pancreatic cancer progression. -- Abstract: Numerous microRNAs (miRNAs) are reported as differentially expressed in cancer, however the consequence of miRNA deregulation in cancer is unknown for many miRNAs. We report that two miRNAs located on chromosome 17p13, miR-132 and miR-212, are over-expressed in pancreatic adenocarcinoma (PDAC) tissues. Both miRNAs are predicted to target the retinoblastoma tumor suppressor, Rb1. Validation of this interaction was confirmed by luciferase reporter assay and western blot in a pancreatic cancer cell line transfected with pre-miR-212 and pre-miR-132 oligos. Cell proliferation was enhanced in Panc-1 cells transfected with pre-miR-132/-212 oligos. Conversely, antisense oligos to miR-132/-212 reduced cell proliferation and caused a G{sub 2}/M cell cycle arrest. The mRNA of a number of E2F transcriptional targets were increased in cells over expressing miR-132/-212. Exposing Panc-1 cells to the {beta}2 adrenergic receptor agonist, terbutaline, increased the miR-132 and miR-212 expression by 2- to 4-fold. We report that over-expression of miR-132 and miR-212 result in reduced pRb protein in pancreatic cancer cells and that the increase in cell proliferation from over-expression of these miRNAs is likely due to increased expression of several E2F target genes. The {beta}2 adrenergic pathway may play an important role in this novel mechanism.

  18. “Nodal Gap” Induced by the Incommensurate Diagonal Spin Density Modulation in Underdoped High- <mi>Tmi>c> Superconductors

    SciTech Connect (OSTI)

    Zhou, Tao [Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China; Gao, Yi [Nanjing Normal University, Nanjing 210023, China; Zhu, Jian-Xin [Los Alamos National Laboratory, Los Alamos, NM 87545, USA

    2015-01-01

    Recently it was revealed that the whole Fermi surface is fully gapped for several families of underdoped cuprates. The existence of the finite energy gap along the<mi>d>-wave nodal lines (nodal gap) contrasts the common understanding of the<mi>d>-wave pairing symmetry, which challenges the present theories for the high-<mi>Tmi><mi>c>superconductors. Here we propose that the incommensurate diagonal spin-density-wave order can account for the above experimental observation. The Fermi surface and the local density of states are also studied. Our results are in good agreement with many important experiments in high-<mi>Tmi><mi>c>superconductors.

  19. Liver fibrosis causes downregulation of miRNA-150 and miRNA-194 in hepatic stellate cells, and their overexpression causes decreased stellate cell activation.

    E-Print Network [OSTI]

    Wu, Jian; Zern, M A

    2010-01-01

    Liver ?brosis causes downregulation of miRNA-150 and miRNA-and their overexpression causes decreased stellate cellJ, Zern MA. Liver ?brosis causes downregulation of miRNA-150

  20. Analytical Study of Hexapod miRNAs using Phylogenetic Methods

    E-Print Network [OSTI]

    Mishra, A K

    2012-01-01

    MicroRNAs (miRNAs) are a class of non-coding RNAs that regulate gene expression. Identification of total number of miRNAs even in completely sequenced organisms is still an open problem. However, researchers have been using techniques that can predict limited number of miRNA in an organism. In this paper, we have used homology based approach for comparative analysis of miRNA of hexapoda group .We have used Apis mellifera, Bombyx mori, Anopholes gambiae and Drosophila melanogaster miRNA datasets from miRBase repository. We have done pair wise as well as multiple alignments for the available miRNAs in the repository to identify and analyse conserved regions among related species. Unfortunately, to the best of our knowledge, miRNA related literature does not provide in depth analysis of hexapods. We have made an attempt to derive the commonality among the miRNAs and to identify the conserved regions which are still not available in miRNA repositories. The results are good approximation with a small number of mis...

  1. Actinide Thermodynamics at Elevated Temperatures

    SciTech Connect (OSTI)

    Friese, Judah I.; Rao, Linfeng; Xia, Yuanxian; Bachelor, Paula P.; Tian, Guoxin

    2007-11-16

    The postclosure chemical environment in the proposed Yucca Mountain repository is expected to experience elevated temperatures. Predicting migration of actinides is possible if sufficient, reliable thermodynamic data on hydrolysis and complexation are available for these temperatures. Data are scarce and scattered for 25 degrees C, and nonexistent for elevated temperatures. This collaborative project between LBNL and PNNL collects thermodynamic data at elevated temperatures on actinide complexes with inorganic ligands that may be present in Yucca Mountain. The ligands include hydroxide, fluoride, sulfate, phosphate and carbonate. Thermodynamic parameters of complexation, including stability constants, enthalpy, entropy and heat capacity of complexation, are measured with a variety of techniques including solvent extraction, potentiometry, spectrophotometry and calorimetry

  2. BMPs Regulate the Oft Development via miRNAs 

    E-Print Network [OSTI]

    Bai, Yan

    2014-08-04

    c-Jun N-terminal Kinase LAP Latency Associated Peptide LLC Large Latent Complex LTBP Latent Tgf-? Binding Protein MFS Marfan Syndrome mi...

  3. ,"Detroit, MI Natural Gas Pipeline Imports From Canada (MMcf...

    U.S. Energy Information Administration (EIA) Indexed Site

    ,"Worksheet Name","Description"," Of Series","Frequency","Latest Data for" ,"Data 1","Detroit, MI Natural Gas Pipeline Imports From Canada (MMcf)",1,"Annual",2014 ,"Release...

  4. The Sequential Action of miR156 and miR172 Regulates Developmental Timing

    E-Print Network [OSTI]

    Weigel, Detlef

    Planck Institute for Developmental Biology, D-72076 Tu¨ bingen, Germany *Correspondence: spoethig@sas elegans (Moss, 2007; Rougvie, 2005) and plants (Ba¨ urle and Dean, 2006; Chuck and Hake, 2005; Poethig in Moss, 2007; Pasquinelli and Ruvkun, 2002; Rougvie, 2005). These were the first miRNAs to be discovered

  5. Members of the miRNA-200 Family Regulate Olfactory Neurogenesis

    E-Print Network [OSTI]

    Choi, Philip S.

    MicroRNAs (miRNAs) are highly expressed in vertebrate neural tissues, but the contribution of specific miRNAs to the development and function of different neuronal populations is still largely unknown. We report that miRNAs ...

  6. Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells

    SciTech Connect (OSTI)

    Vrba, Lukas; Jensen, Taylor J.; Garbe, James C.; Heimark, Ronald L.; Cress, Anne E.; Dickinson, Sally; Stampfer, Martha R.; Futscher, Bernard W.

    2009-12-23

    BACKGROUND: The microRNA-200 family participates in the maintenance of an epithelial phenotype and loss of its expression can result in epithelial to mesenchymal transition (EMT). Furthermore, the loss of expression of miR-200 family members is linked to an aggressive cancer phenotype. Regulation of the miR-200 family expression in normal and cancer cells is not fully understood. METHODOLOGY/ PRINCIPAL FINDINGS: Epigenetic mechanisms participate in the control of miR-200c and miR-141 expression in both normal and cancer cells. A CpG island near the predicted mir-200c/mir-141 transcription start site shows a striking correlation between miR-200c and miR-141 expression and DNA methylation in both normal and cancer cells, as determined by MassARRAY technology. The CpG island is unmethylated in human miR-200/miR-141 expressing epithelial cells and in miR-200c/miR-141 positive tumor cells. The CpG island is heavily methylated in human miR-200c/miR-141 negative fibroblasts and miR-200c/miR-141 negative tumor cells. Mouse cells show a similar inverse correlation between DNA methylation and miR-200c expression. Enrichment of permissive histone modifications, H3 acetylation and H3K4 trimethylation, is seen in normal miR-200c/miR-141-positive epithelial cells, as determined by chromatin immunoprecipitation coupled to real-time PCR. In contrast, repressive H3K9 dimethylation marks are present in normal miR-200c/miR-141-negative fibroblasts and miR-200c/miR-141 negative cancer cells and the permissive histone modifications are absent. The epigenetic modifier drug, 5-aza-2'-deoxycytidine, reactivates miR-200c/miR-141 expression showing that epigenetic mechanisms play a functional role in their transcriptional control. CONCLUSIONS/ SIGNIFICANCE: We report that DNA methylation plays a role in the normal cell type-specific expression of miR-200c and miR-141 and this role appears evolutionarily conserved, since similar results were obtained in mouse. Aberrant DNA methylation of the miR-200c/141 CpG island is closely linked to their inappropriate silencing in cancer cells. Since the miR-200c cluster plays a significant role in EMT, our results suggest an important role for DNA methylation in the control of phenotypic conversions in normal cells.

  7. miR-92a family and their target genes in tumorigenesis and metastasis

    SciTech Connect (OSTI)

    Li, Molin; Guan, Xingfang; Sun, Yuqiang; Mi, Jun; Shu, Xiaohong; Liu, Fang; Li, Chuangang

    2014-04-15

    The miR-92a family, including miR-25, miR-92a-1, miR-92a-2 and miR-363, arises from three different paralog clusters miR-17-92, miR-106a-363, and miR-106b-25 that are highly conservative in the process of evolution, and it was thought as a group of microRNAs (miRNAs) correlated with endothelial cells. Aberrant expression of miR-92a family was detected in multiple cancers, and the disturbance of miR-92a family was related with tumorigenesis and tumor development. In this review, the progress on the relationship between miR-92a family and their target genes and malignant tumors will be summarized. - Highlights: • Aberrant expression of miR-92a, miR-25 and miR-363 can be observed in many kinds of malignant tumors. • The expression of miR-92a family is regulated by LOH, epigenetic alteration, transcriptional factors such as SP1, MYC, E2F, wild-type p53 etc. • Roles of miR-92a family in tumorigenesis and development: promoting cell proliferation, invasion and metastasis, inhibiting cell apoptosis.

  8. miR-143 Interferes with ERK5 Signaling, and Abrogates Prostate Cancer Progression in Mice

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    miR-143 Interferes with ERK5 Signaling, and Abrogates Prostate Cancer Progression in Mice Cyrielle-regulated kinase-5 (ERK5) activity. We show here that ERK5 is a miR-143 target in prostate cancer. Conclusions: mi, Apparailly F, Fernandez PL, et al. (2009) miR-143 Interferes with ERK5 Signaling, and Abrogates Prostate

  9. NuMI Target Station AHIPA09 10/19/09

    E-Print Network [OSTI]

    McDonald, Kirk

    MI Target Station AHIPA09 10/19/09 Jim Hylen/FNAL Page 11Remote 5-axis lift table Numi target+baffle on liftNuMI Target Station AHIPA09 10/19/09 Jim Hylen/FNAL Page 1 Target Station Infrastructure: The Nu slide overview of NuMI #12;NuMI Target Station AHIPA09 10/19/09 Jim Hylen/FNAL Page 2 NuMI produces

  10. Regulation of Synaptic Structure and Function by FMRP-Associated MicroRNAs miR-125b and miR-132

    E-Print Network [OSTI]

    Edbauer, Dieter

    MicroRNAs (miRNAs) are noncoding RNAs that suppress translation of specific mRNAs. The miRNA machinery interacts with fragile X mental retardation protein (FMRP), which functions as translational repressor. We show that ...

  11. miRNA-205 affects infiltration and metastasis of breast cancer

    SciTech Connect (OSTI)

    Wang, Zhouquan; Department of Tumor, SenGong Hospital of Shaanxi, Xi’an 710300 ; Liao, Hehe; Deng, Zhiping; Yang, Po; Du, Ning; Zhanng, Yunfeng; Ren, Hong

    2013-11-08

    Highlights: •We detected expression of miR-205 in breast cancer cell lines and tissue samples. •We suggest miR-205 is downregulated in human breast cancer tissues and MCF7 cells. •We suggest the lower expression of miR-205 play a role in breast cancer onset. •These data suggest that miR-205 directly targets HER3 in human breast cancer. -- Abstract: Background: An increasing number of studies have shown that miRNAs are commonly deregulated in human malignancies, but little is known about the function of miRNA-205 (miR-205) in human breast cancer. The present study investigated the influence of miR-205 on breast cancer malignancy. Methods: The expression level of miR-205 in the MCF7 breast cancer cell line was determined by quantitative (q)RT-PCR. We then analyzed the expression of miR-205 in breast cancer and paired non-tumor tissues. Finally, the roles of miR-205 in regulating tumor proliferation, apoptosis, migration, and target gene expression were studied by MTT assay, flow cytometry, qRT-PCR, Western blotting and luciferase assay. Results: miR-205 was downregulated in breast cancer cells or tissues compared with normal breast cell lines or non-tumor tissues. Overexpression of miR-205 reduced the growth and colony-formation capacity of MCF7 cells by inducing apoptosis. Overexpression of miR-205 inhibited MCF7 cell migration and invasiveness. By bioinformation analysis, miR-205 was predicted to bind to the 3? untranslated regions of human epidermal growth factor receptor (HER)3 mRNA, and upregulation of miR-205 reduced HER3 protein expression. Conclusion: miR-205 is a tumor suppressor in human breast cancer by post-transcriptional inhibition of HER3 expression.

  12. miR-132, an experience-dependent microRNA, is essential for visual cortex plasticity

    E-Print Network [OSTI]

    Mellios, Nikolaos

    Using quantitative analyses, we identified microRNAs (miRNAs) that were abundantly expressed in visual cortex and that responded to dark rearing and/or monocular deprivation. The most substantially altered miRNA, miR-132, ...

  13. High-flux magnetorheology at elevated temperatures

    E-Print Network [OSTI]

    Ocalan, Murat

    Commercial applications of magnetorheological (MR) fluids often require operation at elevated temperatures as a result of surrounding environmental conditions or intense localized viscous heating. Previous experimental ...

  14. FEMA - National Flood Insurance Program Elevation Certificate...

    Open Energy Info (EERE)

    Certificate and Instructions Jump to: navigation, search OpenEI Reference LibraryAdd to library Web Site: FEMA - National Flood Insurance Program Elevation Certificate and...

  15. Molecular Cell Loss of miR-200 Inhibition of Suz12 Leads to

    E-Print Network [OSTI]

    In an inducible oncogenesis model, the miR-200 family is inhibited during CSC formation but not trans- formation

  16. Discovery of miRNA-regulated processes in mammalian development

    E-Print Network [OSTI]

    Young, Amanda Garfinkel

    2010-01-01

    The genomes of plants and animals encode hundreds of non-coding ~22nt RNAs termed "microRNAs" (miRNAs). These RNAs guide the sequence-specific inhibition of translation and destabilization of mRNA targets through short ...

  17. Radiosensitizing Effects of Ectopic miR-101 on Non-Small-Cell Lung Cancer Cells Depend on the Endogenous miR-101 Level

    SciTech Connect (OSTI)

    Chen, Susie; Wang Hongyan; Ng, Wooi Loon; Curran, Walter J.; Wang Ya

    2011-12-01

    Purpose: Previously, we showed that ectopic miR-101 could sensitize human tumor cells to radiation by targeting ATM and DNA-PK catalytic subunit (DNA-PKcs) to inhibit DNA repair, as the endogenous miR-101 levels are low in tumors in general. However, the heterogeneity of human cancers may result in an exception. The purpose of this study was to test the hypothesis that a few tumor cell lines with a high level of endogenous miR-101 would prove less response to ectopic miR-101. Methods and Materials: Fourteeen non-small-cell lung cancer (NSCLC) cell lines and one immortalized non-malignant lung epithelial cell line (NL20) were used for comparing endogenous miR-101 levels by real-time reverse transcription-polymerase chain reaction. Based on the different miR-101 levels, four cell lines with different miR-101 levels were chosen for transfection with a green fluorescent protein-lentiviral plasmid encoding miR-101. The target protein levels were measured by using Western blotting. The radiosensitizing effects of ectopic miR-101 on these NSCLC cell lines were determined by a clonogenic assay and xenograft mouse model. Results: The endogenous miR-101 level was similar or lower in 13 NSCLC cell lines but was 11-fold higher in one cell line (H157) than in NL20 cells. Although ectopic miR-101 efficiently decreased the ATM and DNA-PKcs levels and increased the radiosensitization level in H1299, H1975, and A549 cells, it did not change the levels of the miR-101 targets or radiosensitivity in H157 cells. Similar results were observed in xenograft mice. Conclusions: A small number of NSCLC cell lines could have a high level of endogenous miR-101. The ectopic miR-101 was able to radiosensitize most NSCLC cells, except for the NSCLC cell lines that had a much higher endogenous miR-101 level. These results suggest that when we choose one miRNA as a therapeutic tool, the endogenous level of the miRNA in each tumor should be considered.

  18. miR-153 and miR-335, Ethanol Sensitive MicroRNAs, Control NSC/NPC Maturation during Fetal Brain Development 

    E-Print Network [OSTI]

    Tsai, Pai Chi

    2014-05-05

    conclude that miR-335 and miR-153 act as molecular brakes to prevent NSCs/NPCs early maturation by regulating cell differentiation genes during the second trimester, and ethanol leads to organizational defects in the developing cerebral cortex through...

  19. Appending High-Resolution Elevation Data to GPS Speed Traces for Vehicle Energy Modeling and Simulation

    SciTech Connect (OSTI)

    Wood, E.; Burton, E.; Duran, A.; Gonder, J.

    2014-06-01

    Accurate and reliable global positioning system (GPS)-based vehicle use data are highly valuable for many transportation, analysis, and automotive considerations. Model-based design, real-world fuel economy analysis, and the growing field of autonomous and connected technologies (including predictive powertrain control and self-driving cars) all have a vested interest in high-fidelity estimation of powertrain loads and vehicle usage profiles. Unfortunately, road grade can be a difficult property to extract from GPS data with consistency. In this report, we present a methodology for appending high-resolution elevation data to GPS speed traces via a static digital elevation model. Anomalous data points in the digital elevation model are addressed during a filtration/smoothing routine, resulting in an elevation profile that can be used to calculate road grade. This process is evaluated against a large, commercially available height/slope dataset from the Navteq/Nokia/HERE Advanced Driver Assistance Systems product. Results will show good agreement with the Advanced Driver Assistance Systems data in the ability to estimate road grade between any two consecutive points in the contiguous United States.

  20. HABITAT PROFILE New Hampshire Wildlife Action PlanB-10

    E-Print Network [OSTI]

    New Hampshire, University of

    HABITAT PROFILE New Hampshire Wildlife Action PlanB-10 Associated Species: Timber rattlesnake. Foss, Audubon Society of New Hampshire Element 1: Distribution and Habitat 1.1 Habitat description Appalachian oak pine forest systems are found mostly below 900 ft elevation in southern New Hampshire south

  1. DLEU2, frequently deleted in malignancy, functions as a critical host gene of the cell cycle inhibitory microRNAs miR-15a and miR-16-1

    SciTech Connect (OSTI)

    Lerner, Mikael; Harada, Masako; Loven, Jakob; Castro, Juan; Davis, Zadie; Oscier, David; Henriksson, Marie; Sangfelt, Olle; Grander, Dan; Corcoran, Martin M.

    2009-10-15

    The microRNAs miR-15a and miR-16-1 are downregulated in multiple tumor types and are frequently deleted in chronic lymphocytic leukemia (CLL), myeloma and mantle cell lymphoma. Despite their abundance in most cells the transcriptional regulation of miR-15a/16-1 remains unclear. Here we demonstrate that the putative tumor suppressor DLEU2 acts as a host gene of these microRNAs. Mature miR-15a/miR-16-1 are produced in a Drosha-dependent process from DLEU2 and binding of the Myc oncoprotein to two alterative DLEU2 promoters represses both the host gene transcript and levels of mature miR-15a/miR-16-1. In line with a functional role for DLEU2 in the expression of the microRNAs, the miR-15a/miR-16-1 locus is retained in four CLL cases that delete both promoters of this gene and expression analysis indicates that this leads to functional loss of mature miR-15a/16-1. We additionally show that DLEU2 negatively regulates the G1 Cyclins E1 and D1 through miR-15a/miR-16-1 and provide evidence that these oncoproteins are subject to miR-15a/miR-16-1-mediated repression under normal conditions. We also demonstrate that DLEU2 overexpression blocks cellular proliferation and inhibits the colony-forming ability of tumor cell lines in a miR-15a/miR-16-1-dependent way. Together the data illuminate how inactivation of DLEU2 promotes cell proliferation and tumor progression through functional loss of miR-15a/miR-16-1.

  2. Groundwater protection for the NuMI project

    SciTech Connect (OSTI)

    Wehmann, A.; Smart, W.; Menary, S.; Hylen, J.; Childress, S.

    1997-10-01

    The physics requirements for the long base line neutrino oscillation experiment MINOS dictate that the NuMI beamline be located in the aquifer at Fermilab. A methodology is described for calculating the level of radioactivation of groundwater caused by operation of this beamline. A conceptual shielding design for the 750 meter long decay pipe is investigated which would reduce radioactivation of the groundwater to below government standards. More economical shielding designs to meet these requirements are being explored. Also, information on local geology, hydrogeology, government standards, and a glossary have been included.

  3. DOE - Office of Legacy Management -- Star Cutter Corp - MI 15

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouth DakotaRobbins and Myers Co - OHStar Cutter Corp - MI 15 FUSRAP

  4. DOE - Office of Legacy Management -- Westinghouse Naval Ordnance - MI 02

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouth DakotaRobbins and Myers Co -VANaval Ordnance - MI 02 FUSRAP

  5. DOE - Office of Legacy Management -- Wolverine Tube Division - MI 05

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouth DakotaRobbins and Myers Co -VANaval Ordnance - MI

  6. REC Silicon formerly ASiMI | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page onRAPID/Geothermal/Exploration/Colorado <RAPID/Geothermal/Water Use/NevadaaTools < RAPID79.14Silicon formerly ASiMI

  7. MHK Technologies/Mi2 | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION J APPENDIXsource HistoryScenarios Towards 2050Enermar < MHKHydro HelixLangleeMi2 < MHK

  8. Title: Canadian Digital Elevation Model (DEM) Data Creator /

    E-Print Network [OSTI]

    , Ontario, Prince Edward Island, Quebec, Saskatchewan, Yukon Keywords (Subject): Contours, Digital Elevation

  9. UNIVERSITY OF TORONTO WORKING AT ELEVATED PLACES

    E-Print Network [OSTI]

    Chan, Hue Sun

    in elevated locations at the University are faced with a potential risk of falling. Persons below these work areas may be at risk from falling objects. These hazards must be significantly reduced through the use including a site specific work plan; Provide notice to the Ontario Ministry of Labour of the nature

  10. Polyetheretherketone Membranes for Elevated Temperature PEMFCs

    E-Print Network [OSTI]

    Weidner, John W.

    Polyetheretherketone Membranes for Elevated Temperature PEMFCs Balasubramanian Lakshmanan exchange membrane fuel cells PEMFCs . For example, the current from a MEA made from PEEK membrane at 0.6 V, 2003. Proton exchange membrane fuel cells PEMFCs running on hy- drogen are an integral part

  11. Hepatitis C Virus Infection and Hepatic Stellate Cell Activation Downregulate miR-29: miR-29 Overexpression Reduces Hepatitis C Viral Abundance in Culture

    E-Print Network [OSTI]

    Bandyopadhyay, Sarmistha

    Background.?Chronic hepatitis C virus (HCV)–induced liver fibrosis involves upregulation of transforming growth factor (TGF)–? and subsequent hepatic stellate cell (HSC) activation. MicroRNAs (miRNAs) regulate HCV infection ...

  12. Global identification of miRNAs and targets in Populus euphratica under salt stress

    E-Print Network [OSTI]

    Deng, Xing-Wang

    Global identification of miRNAs and targets in Populus euphratica under salt stress Bosheng Li, a typical hydro-halophyte, is ideal for studying salt stress responses in woody plants. MicroRNAs (miRNA may regulate tolerance to salt stress but this has not been widely studied in P. euphratica

  13. Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres

    E-Print Network [OSTI]

    Ji, Qing; Hao, Xinbao; Meng, Yang; Zhang, Min; DeSano, Jeffrey; Fan, Daiming; Xu, Liang

    2008-09-21

    Background: MicroRNAs (miRNAs), some of which function as oncogenes or tumor suppressor genes, are involved in carcinogenesis via regulating cell proliferation and/or cell death. MicroRNA miR-34 was recently found to be a direct target of p53...

  14. Mi2beta Is Required for c-Globin Gene Silencing: Temporal Assembly of a GATA-1-FOG-1-Mi2 Repressor Complex in b-YAC Transgenic Mice

    E-Print Network [OSTI]

    Costa, Flá via C.; Fedosyuk, Halyna; Chazelle, Allen M.; Neades, Renee Y.; Peterson, Kenneth R.

    2012-12-20

    Mi2b Is Required for c-Globin Gene Silencing: Temporal Assembly of a GATA-1-FOG-1-Mi2 Repressor Complex in b-YAC Transgenic Mice Fla´via C. Costa1¤, Halyna Fedosyuk1, Allen M. Chazelle1, Renee Y. Neades1, Kenneth R. Peterson1,2* 1Department... hemoglobin. A GATA-1-FOG-1-Mi2 repressor complex was recently demonstrated to be recruited to the 2566 GATA motif of the Ac-globin gene. We show that Mi2b is essential for c-globin gene silencing using Mi2b conditional knockout b-YAC transgenic mice...

  15. miR-128 and its target genes in tumorigenesis and metastasis

    SciTech Connect (OSTI)

    Li, Molin, E-mail: molin_li@hotmail.com [Dalian Medical University, Dalian 116044 (China); Fu, Weiming [Center for Food Safety and Environmental Technology, Guangzhou Institute of Advanced Technology, Chinese Academy of Sciences, Guangzhou 511458 (China); Wo, Lulu; Shu, Xiaohong [Dalian Medical University, Dalian 116044 (China); Liu, Fang [The second affiliated hospital of Dalian Medical University, Dalian 116023 (China); Li, Chuangang, E-mail: li_chuangang@sina.com [The second affiliated hospital of Dalian Medical University, Dalian 116023 (China)

    2013-12-10

    MicroRNAs (miRNAs) are a class of endogenous, non-coding, 18–24 nucleotide length single-strand RNAs that could modulate gene expression at post-transcriptional level. Previous studies have shown that miR-128 enriched in the brain plays an important role in the development of nervous system and the maintenance of normal physical functions. Aberrant expression of miR-128 has been detected in many types of human tumors and its validated target genes are involved in cancer-related biological processes such as cell proliferation, differentiation and apoptosis. In this review, we will summarize the roles of miR-128 and its target genes in tumorigenesis and metastasis. - Highlights: • Aberrant expression of miR-128 can be observed in many kinds of malignant tumors. • The molecular mechanisms regulating miR-128 expression are elucidated. • Roles of miR-128 and its target genes in tumorigenesis and metastasis are summarized.

  16. MiR-150, A Novel and Potent Regulator for MLL-AF9 Leukemic Stem Cells 

    E-Print Network [OSTI]

    Cheruku, Patali

    2013-02-18

    Designing the miR-150 sponge primer set .................................................................. 10 Preparation of the DNA fragment containing the miR-150 sponge sequence ............ 10 Construction of pcDNA5-CMV-d2eGFP-miR150sp... protocol. Enzymatic digestion with XhoI and ApaI confirmed the insertion of the miR-150 sponge fragment. The miR-150sp-eGFP sequence (Figure 1) was then amplified using polymerase chain reaction (PCR) with the BamHI forward and SalI reverse primers, gel...

  17. Gas-Alloy Interactions at Elevated Temperatures

    SciTech Connect (OSTI)

    Arroyave, Raymundo; Gao, Michael

    2012-12-01

    The understanding of the stability of metals and alloys against oxidation and other detrimental reactions, to the catalysis of important chemical reactions and the minimization of defects associated with processing and synthesis have one thing in common: At the most fundamental level, all these scientific/engineering problems involve interactions between metals and alloys (in the solid or liquid state) and gaseous atmospheres at elevated temperatures. In this special issue, we have collected a series of articles that illustrate the application of different theoretical, computational, and experimental techniques to investigate gas-alloy interactions.

  18. Soil carbon and nitrogen cycling and storage throughout the soil profile in a sweetgum plantation after 11 years of

    E-Print Network [OSTI]

    Soil carbon and nitrogen cycling and storage throughout the soil profile in a sweetgum plantation partitioning of carbon (C) to fine roots under elevated [CO2], especially deep in the soil profile, could alter soil C and nitrogen (N) cycling in forests. After more than 11 years of free-air CO2 enrichment

  19. Computer-Generated Papercutting Jie Xu1 Craig S. Kaplan1 Xiaofeng Mi2

    E-Print Network [OSTI]

    Waterloo, University of

    Computer-Generated Papercutting Jie Xu1 Craig S. Kaplan1 Xiaofeng Mi2 1Computer Graphics Lab David Pattern #12;Related Work Kaplan and Salesin, TOG 2004 Kaplan, GI 2005 #12;Geometric Patterns Geometric

  20. Modulation of Ago-miRNA regulatory networks by cis-sequence elements and target competition

    E-Print Network [OSTI]

    Bosson, Andrew D. (Andrew David)

    2014-01-01

    regulators of gene expression in a wide range of organisms and biological processes. Each miRNA guides Argonaute (Ago) protein complexes to target and repress hundreds of genes in a sequence-dependent manner. To identify ...

  1. Simulations of neutron multiplicity measurements with MCNP-PoliMi.

    SciTech Connect (OSTI)

    Mattingly, John K.; Pozzi, Sara A. (University of Michigan); Clarke, Shaun D. (University of Michigan); Dennis, Ben D. (University of Michigan); Miller, Eric C.

    2010-09-01

    The heightened focus on nuclear safeguards and accountability has increased the need to develop and verify simulation tools for modeling these applications. The ability to accurately simulate safeguards techniques, such as neutron multiplicity counting, aids in the design and development of future systems. This work focuses on validating the ability of the Monte Carlo code MCNPX-PoliMi to reproduce measured neutron multiplicity results for a highly multiplicative sample. The benchmark experiment for this validation consists of a 4.5-kg sphere of plutonium metal that was moderated by various thicknesses of polyethylene. The detector system was the nPod, which contains a bank of 15 3He detectors. Simulations of the experiments were compared to the actual measurements and several sources of potential bias in the simulation were evaluated. The analysis included the effects of detector dead time, source-detector distance, density, and adjustments made to the value of {nu}-bar in the data libraries. Based on this analysis it was observed that a 1.14% decrease in the evaluated value of {nu}-bar for 239Pu in the ENDF-VII library substantially improved the accuracy of the simulation.

  2. Solar Flare Measurements with STIX and MiSolFA

    E-Print Network [OSTI]

    Casadei, Diego

    2014-01-01

    Solar flares are the most powerful events in the solar system and the brightest sources of X-rays, often associated with emission of particles reaching the Earth and causing geomagnetic storms, giving problems to communication, airplanes and even black-outs. X-rays emitted by accelerated electrons are the most direct probe of solar flare phenomena. The Micro Solar-Flare Apparatus (MiSolFA) is a proposed compact X-ray detector which will address the two biggest issues in solar flare modeling. Dynamic range limitations prevent simultaneous spectroscopy with a single instrument of all X-ray emitting regions of a flare. In addition, most X-ray observations so far are inconsistent with the high anisotropy predicted by the models usually adopted for solar flares. Operated at the same time as the STIX instrument of the ESA Solar Orbiter mission, at the next solar maximum (2020), they will have the unique opportunity to look at the same flare from two different directions: Solar Orbiter gets very close to the Sun wit...

  3. Traction sheave elevator, hoisting unit and machine space

    DOE Patents [OSTI]

    Hakala, Harri (Hyvinkaa, FI); Mustalahti, Jorma (Hyvinkaa, FI); Aulanko, Esko (Kerava, FI)

    2000-01-01

    Traction sheave elevator consisting of an elevator car moving along elevator guide rails, a counterweight moving along counterweight guide rails, a set of hoisting ropes (3) on which the elevator car and counterweight are suspended, and a drive machine unit (6) driving a traction sheave (7) acting on the hoisting ropes (3) and placed in the elevator shaft. The drive machine unit (6) is of a flat construction. A wall of the elevator shaft is provided with a machine space with its open side facing towards the shaft, the essential parts of the drive machine unit (6) being placed in the space. The hoisting unit (9) of the traction sheave elevator consists of a substantially discoidal drive machine unit (6) and an instrument panel (8) mounted on the frame (20) of the hoisting unit.

  4. Instant Profiling: Instrumentation Sampling for Profiling Datacenter Applications

    E-Print Network [OSTI]

    Cortes, Corinna

    Instant Profiling: Instrumentation Sampling for Profiling Datacenter Applications Hyoun Kyu Cho Profile-guided optimization possesses huge potential to save costs for datacenters. Hardware performance programmers find code regions to optimize by monitoring datacenter applications continuously on live traffic

  5. EIA - State Nuclear Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submitKansas Nuclear Profile 2010 Kansas profile KansasHampshire Nuclear Profile 2010

  6. EIA - State Nuclear Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submitKansas Nuclear Profile 2010 Kansas profile KansasHampshire Nuclear Profile

  7. EIA - State Nuclear Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submitKansas Nuclear Profile 2010 Kansas profile KansasHampshire Nuclear ProfileYork

  8. EIA - State Nuclear Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submitKansas Nuclear Profile 2010 Kansas profile KansasHampshireTexas profile Texas

  9. EIA - State Nuclear Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submitKansas Nuclear Profile 2010 Kansas profile KansasHampshireTexas profile

  10. EIA - State Nuclear Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submitKansas Nuclear Profile 2010 Kansas profile KansasHampshireTexas profileVirginia

  11. C-Myc negatively controls the tumor suppressor PTEN by upregulating miR-26a in glioblastoma multiforme cells

    SciTech Connect (OSTI)

    Guo, Pin; Nie, Quanmin; Lan, Jin; Ge, Jianwei [Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127 (China)] [Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127 (China); Qiu, Yongming, E-mail: qiuzhoub@hotmail.com [Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127 (China) [Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127 (China); Shanghai Institute of Head Trauma, Shanghai 200127 (China); Mao, Qing, E-mail: maoq@netease.com [Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127 (China) [Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127 (China); Shanghai Institute of Head Trauma, Shanghai 200127 (China)

    2013-11-08

    Highlights: •The c-Myc oncogene directly upregulates miR-26a expression in GBM cells. •ChIP assays demonstrate that c-Myc interacts with the miR-26a promoter. •Luciferase reporter assays show that PTEN is a specific target of miR-26a. •C-Myc–miR-26a suppression of PTEN may regulate the PTEN/AKT pathway. •Overexpression of c-Myc enhances the proliferative capacity of GBM cells. -- Abstract: The c-Myc oncogene is amplified in many tumor types. It is an important regulator of cell proliferation and has been linked to altered miRNA expression, suggesting that c-Myc-regulated miRNAs might contribute to tumor progression. Although miR-26a has been reported to be upregulated in glioblastoma multiforme (GBM), the mechanism has not been established. We have shown that ectopic expression of miR-26a influenced cell proliferation by targeting PTEN, a tumor suppressor gene that is inactivated in many common malignancies, including GBM. Our findings suggest that c-Myc modulates genes associated with oncogenesis in GBM through deregulation of miRNAs via the c-Myc–miR-26a–PTEN signaling pathway. This may be of clinical relevance.

  12. Elevated temperature forming method and preheater apparatus

    DOE Patents [OSTI]

    Krajewski, Paul E; Hammar, Richard Harry; Singh, Jugraj; Cedar, Dennis; Friedman, Peter A; Luo, Yingbing

    2013-06-11

    An elevated temperature forming system in which a sheet metal workpiece is provided in a first stage position of a multi-stage pre-heater, is heated to a first stage temperature lower than a desired pre-heat temperature, is moved to a final stage position where it is heated to a desired final stage temperature, is transferred to a forming press, and is formed by the forming press. The preheater includes upper and lower platens that transfer heat into workpieces disposed between the platens. A shim spaces the upper platen from the lower platen by a distance greater than a thickness of the workpieces to be heated by the platens and less than a distance at which the upper platen would require an undesirably high input of energy to effectively heat the workpiece without being pressed into contact with the workpiece.

  13. Polymer Physics Research Profile

    E-Print Network [OSTI]

    Giger, Christine

    Polymer Physics Research Profile Our main interests are the theory of simplification and some behavior on different autonomous levels of description. Our favorite applications range from polymer + Nonequilibrium Thermodynamics + Coarse Graining + Soft Matter + Polymer Physics + Rheology + Competences

  14. EIA - State Nuclear Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submitKansas Nuclear Profile 2010 Kansas profile Kansas total

  15. EIA - State Nuclear Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submitKansas Nuclear Profile 2010 Kansas profile Kansas

  16. Importance of Elevation and Temperature Inversions for the Interpretat...

    Open Energy Info (EERE)

    Importance of Elevation and Temperature Inversions for the Interpretation of Thermal Infrared Satellite Images Used in Geothermal Exploration Jump to: navigation, search OpenEI...

  17. miR-421 induces cell proliferation and apoptosis resistance in human nasopharyngeal carcinoma via downregulation of FOXO4

    SciTech Connect (OSTI)

    Chen, Liang; Department of Otolaryngology, Guangzhou General Hospital of PLA Guangzhou Command, Guangzhou 510010 ; Tang, Yanping; Wang, Jian; Yan, Zhongjie; Xu, Ruxiang

    2013-06-14

    Highlights: •miR-421 is upregulated in nasopharyngeal carcinoma. •miR-421 induces cell proliferation and apoptosis resistance. •FOXO4 is a direct and functional target of miR-421. -- Abstract: microRNAs have been demonstrated to play important roles in cancer development and progression. Hence, identifying functional microRNAs and better understanding of the underlying molecular mechanisms would provide new clues for the development of targeted cancer therapies. Herein, we reported that a microRNA, miR-421 played an oncogenic role in nasopharyngeal carcinoma. Upregulation of miR-421 induced, whereas inhibition of miR-421 repressed cell proliferation and apoptosis resistance. Furthermore, we found that upregulation of miR-421 inhibited forkhead box protein O4 (FOXO4) signaling pathway following downregulation of p21, p27, Bim and FASL expression by directly targeting FOXO4 3?UTR. Additionally, we demonstrated that FOXO4 expression is critical for miR-421-induced cell growth and apoptosis resistance. Taken together, our findings not only suggest that miR-421 promotes nasopharyngeal carcinoma cell proliferation and anti-apoptosis, but also uncover a novel regulatory mechanism for inactivation of FOXO4 in nasopharyngeal carcinoma.

  18. Strontium sorption on hematite at elevated temperatures

    SciTech Connect (OSTI)

    Karasyova, O.N.; Ivanova, L.I.; Lakshtanov, L.Z.; Loevgren, L.

    1999-12-15

    Acid-base reactions and surface complexation of Sr(II) at the hematite/water interface have been studied by means of potentiometric titrations at three different temperatures: 25, 50, and 75 C. Equilibrium measurements were performed in 0.1 M NaCl. In the evaluation of equilibrium models for the acid-base reactions and complexation reactions in the three-component system H{sup +} -({triple{underscore}bond}FeOH)-Sr{sup 2+}, the constant capacitance model was applied. During the titrations with Sr, aliquots of the suspension were sampled at in several points. The aqueous concentrations of Sr were analyzed by atomic absorption spectrometry. Treatment of data included tests for formation of both inner-sphere and outer-sphere complexes of different stoichiometric composition. The proposed equilibrium model consists of the following surface complexes of inner sphere type: {triple{underscore}bond}FeOHSr{sup 2+} and {triple{underscore}bond}FeOSrOH. Besides the stability constants for the surface complexes, the thermodynamic parameters {Delta}H and {Delta}S were evaluated. The combined effect of a decrease in pH{sub pzc} with increasing temperature and positive enthalpies of surface complex formation favors adsorption of Sr at elevated temperatures.

  19. Single-molecule modeling of mRNA degradation by miRNA: Lessons from data

    E-Print Network [OSTI]

    Celine Sin; Davide Chiarugi; Angelo Valleriani

    2014-10-20

    Recent experimental results on the effect of miRNA on the decay of its target mRNA have been analyzed against a previously hypothesized single molecule degradation pathway. According to that hypothesis, the silencing complex (miRISC) first interacts with its target mRNA and then recruits the protein complexes associated with NOT1 and PAN3 to trigger deadenylation (and subsequent degradation) of the target mRNA. Our analysis of the experimental decay patterns allowed us to refine the structure of the degradation pathways at the single molecule level. Surprisingly, we found that if the previously hypothesized network was correct, only about 7% of the target mRNA would be regulated by the miRNA mechanism, which is inconsistent with the available knowledge. Based on systematic data analysis, we propose the alternative hypothesis that NOT1 interacts with miRISC before binding to the target mRNA. Moreover, we show that when miRISC binds alone to the target mRNA, the mRNA is degraded more slowly, probably through a deadenylation-independent pathway. The new biochemical pathway we propose both fits the data and paves the way for new experimental work to identify new interactions.

  20. EIA - State Nuclear Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submitKansas Nuclear Profile 2010 Kansas profile Kansas total electric power

  1. EIA - State Nuclear Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submitKansas Nuclear Profile 2010 Kansas profile Kansas total electric powerLouisiana

  2. EIA - State Nuclear Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submitKansas Nuclear Profile 2010 Kansas profile Kansas total electric

  3. EIA - State Nuclear Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submitKansas Nuclear Profile 2010 Kansas profile Kansas total electricMassachusetts

  4. EIA - State Nuclear Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submitKansas Nuclear Profile 2010 Kansas profile Kansas totalMinnesota Nuclear

  5. EIA - State Nuclear Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submitKansas Nuclear Profile 2010 Kansas profile Kansas totalMinnesota

  6. EIA - State Nuclear Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submitKansas Nuclear Profile 2010 Kansas profile Kansas totalMinnesotaMissouri

  7. EIA - State Nuclear Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submitKansas Nuclear Profile 2010 Kansas profile KansasHampshire Nuclear

  8. EIA - State Nuclear Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submitKansas Nuclear Profile 2010 Kansas profile KansasHampshire NuclearOhio Nuclear

  9. EIA - State Nuclear Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submitKansas Nuclear Profile 2010 Kansas profile KansasHampshire NuclearOhio

  10. EIA - State Nuclear Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submitKansas Nuclear Profile 2010 Kansas profile KansasHampshire NuclearOhioSouth

  11. EIA - State Nuclear Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submitKansas Nuclear Profile 2010 Kansas profile KansasHampshire

  12. EIA - State Nuclear Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submitKansas Nuclear Profile 2010 Kansas profile KansasHampshireTexas

  13. EIA - State Nuclear Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submitKansas Nuclear Profile 2010 Kansas profile KansasHampshireTexasWisconsin

  14. Impact of Storm Water Recharge Practices on Boston Groundwater Elevations

    E-Print Network [OSTI]

    Vogel, Richard M.

    Impact of Storm Water Recharge Practices on Boston Groundwater Elevations Brian F. Thomas, S periodically experienced a decline in groundwater elevations and the associated deterioration of untreated wood a groundwater conservation overlay district enforced by city zoning boards to require storm water recharge

  15. Widespread foliage d15 N depletion under elevated CO2

    E-Print Network [OSTI]

    Thomas, David D.

    Widespread foliage d15 N depletion under elevated CO2: inferences for the nitrogen cycle H O R M O an integrated assessment of the nitrogen (N) cycle and whether it is influenced by rising atmospheric CO2 concentration. We tested the hypothesis that elevated CO2 significantly changes foliage d15 N in a wide range

  16. Profiling microbial communities in manganese remediation systems treating coal mine1 Dominique L. Chaput1

    E-Print Network [OSTI]

    Burgos, William

    1 Profiling microbial communities in manganese remediation systems treating coal mine1 drainage2 3 coal mines can contain extremely high manganese19 levels. Removing this metal is an ongoing challenge Coal mine drainage (CMD) from operating and abandoned mines often contains39 elevated concentrations

  17. RESEARCH AND INNOVATION PROFILE

    E-Print Network [OSTI]

    Haase, Markus

    RESEARCH AND INNOVATION PROFILE Create knowledge. Make an impact. Leeds University Business School #12;Contents 01 Leeds University Business School research and you | 04 02 A collaborative approach | 06 03 Developing research leaders | 08 04 Impacting on people's lives | 10 05 Accounting and Finance

  18. Low profile thermite igniter

    DOE Patents [OSTI]

    Halcomb, Danny L. (Camden, OH); Mohler, Jonathan H. (Spring Valley, OH)

    1991-03-05

    A thermite igniter/heat source comprising a housing, high-density thermite, and low-density thermite. The housing has a relatively low profile and can focus energy by means of a torch-like ejection of hot reaction products and is externally ignitable.

  19. Ion-lithium collision dynamics studied with an in-ring MOTReMi

    E-Print Network [OSTI]

    Fischer, D; Goullon, J; Grieser, M; Hubele, R; de Jesus, V L B; Kelkar, A; LaForge, A; Lindenblatt, H; Misra, D; Najjari, B; Schneider, K; Schulz, M; Sell, M; Wang, X

    2012-01-01

    We present a novel experimental tool allowing for kinematically complete studies of break-up processes of laser-cooled atoms. This apparatus, the 'MOTReMi', is a combination of a magneto-optical trap (MOT) and a Reaction Microscope (ReMi). Operated in an ion-storage ring, the new setup enables to study the dynamics in swift ion-atom collisions on an unprecedented level of precision and detail. In first experiments on collisions with 1.5 MeV/amu O$^{8+}$-Li the pure ionization of the valence electron as well as ionization-excitation of the lithium target has been investigated.

  20. Elevated lactate dehydrogenase activity and increased cardiovascular mortality in the arsenic-endemic areas of southwestern Taiwan

    SciTech Connect (OSTI)

    Liao, Ya-Tang; Graduate Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taiwan; Genomics Research Center, Academia Sinica, Taiwan ; Chen, Chien-Jen; Genomics Research Center, Academia Sinica, Taiwan ; Li, Wan-Fen; Hsu, Ling-I; Tsai, Li-Yu; Huang, Yeou-Lih; Sun, Chien-Wen; Chen, Wei J.; Wang, Shu-Li; Department of Public Health, College of Public Health, China Medical University, Taichung, Taiwan

    2012-08-01

    Arsenic ingestion has been linked to increasing global prevalence of and mortality from cardiovascular disease (CVD); arsenic can be removed from drinking water to reduce related health effects. Lactate dehydrogenase (LDH) is used for the evaluation of acute arsenic toxicity in vivo and in vitro, but it is not validated for the evaluation of long-term, chronic arsenic exposure. The present study examined the long-term effect of chronic arsenic exposure on CVD and serum LDH levels, after consideration of arsenic metabolism capacity. A total of 380 subjects from an arseniasis-endemic area and 303 from a non-endemic area of southwestern Taiwan were recruited in 2002. Various urinary arsenic species were analyzed using high-performance liquid chromatography (HPLC) and hydride generation systems. Fasting serum was used for quantitative determination of the total LDH activity. A significant dose–response relationship was observed between arsenic exposure and LDH elevation, independent of urinary arsenic profiles (P < 0.001). Furthermore, abnormal LDH elevation was associated with CVD mortality after adjustment for Framingham risk scores for 10-year CVD and arsenic exposure (hazard ratio, 3.98; 95% confidence interval, 1.07–14.81). LDH was elevated in subjects with arsenic exposure in a dose-dependent manner. LDH is a marker of arsenic toxicity associated with CVD mortality. Results of this study have important implications for use in ascertaining long-term arsenic exposure risk of CVD. -- Highlights: ? We showed that arsenic exposure was correlated with LDH elevation. ? LDH elevation was related to arsenic methylation capacity. ? Abnormal LDH elevation can be a marker of susceptibility to CVD mortality.

  1. Representative Atmospheric Plume Development for Elevated Releases

    SciTech Connect (OSTI)

    Eslinger, Paul W.; Lowrey, Justin D.; McIntyre, Justin I.; Miley, Harry S.; Prichard, Andrew W.

    2014-03-03

    An atmospheric explosion of a low-yield nuclear device will produce a large number of radioactive isotopes, some of which can be measured with airborne detection systems. However, properly equipped aircraft may not arrive in the region where an explosion occurred for a number of hours after the event. Atmospheric conditions will have caused the radioactive plume to move and diffuse before the aircraft arrives. The science behind predicting atmospheric plume movement has advanced enough that the location of the maximum concentrations in the plume can be determined reasonably accurately in real time, or near real time. Given the assumption that an aircraft can follow a plume, this study addresses the amount of atmospheric dilution expected to occur in a representative plume as a function of time past the release event. The approach models atmospheric transport of hypothetical releases from a single location for every day in a year using the publically available HYSPLIT code. The effective dilution factors for the point of maximum concentration in an elevated plume based on a release of a non-decaying, non-depositing tracer can vary by orders of magnitude depending on the day of the release, even for the same number of hours after the release event. However, the median of the dilution factors based on releases for 365 consecutive days at one site follows a power law relationship in time, as shown in Figure S-1. The relationship is good enough to provide a general rule of thumb for estimating typical future dilution factors in a plume starting at the same point. However, the coefficients of the power law function may vary for different release point locations. Radioactive decay causes the effective dilution factors to decrease more quickly with the time past the release event than the dilution factors based on a non-decaying tracer. An analytical expression for the dilution factors of isotopes with different half-lives can be developed given the power law expression for the non-decaying tracer. If the power-law equation for the median dilution factor, Df, based on a non-decaying tracer has the general form Df=a?×t?^(-b) for time t after the release event, then the equation has the form Df=e^(-?t)×a×t^(-b) for a radioactive isotope, where ? is the decay constant for the isotope.

  2. Company City State Contact Info 21st Century Plastics Corporation Potterville MI www.21stcpc.com

    E-Print Network [OSTI]

    McGaughey, Alan

    Engineered Plastics, LLC Auburn Hills MI www.deltaengineeredplastics.com Detrex Corporation.dutchlandplastics.com E & O Tool & Plastics, Inc. Elk River MN www.eoplastics.com E & T Plastic Rubber & Plastics Corp. Farmington Hills MI www.exoticautomation.com F & D Plastics, Inc

  3. Roles of the MicroRNA miR-31 in tumor metastasis and an experimental system for the unbiased discovery of genes relevant for breast cancer metastasis

    E-Print Network [OSTI]

    Valastyan, Scott J. (Scott John)

    2010-01-01

    In these studies, the microRNA miR-31 was identified as a potent inhibitor of breast cancer metastasis. miR-31 expression levels were inversely associated with the propensity to develop metastatic disease in human breast ...

  4. PROFILE SHAPE PARAMETERIZATION OF JET ELECTRON TEMPERATURE AND DENSITY PROFILES

    E-Print Network [OSTI]

    PROFILE SHAPE PARAMETERIZATION OF JET ELECTRON TEMPERATURE AND DENSITY PROFILES Beatrix Schunke JET temperature profile shapes have been parameterised in terms of the engineering variablesMRK,RI,IRS . In this article, we report the results of the parame- terisation of the Joint European TorusRebut (JET) electron

  5. Reprinted from the Proceedings of the 1998 ASEE North Central Section Meeting, University of Detroit Mercy, Detroit, MI, April 3-4, 1998. ( Best Paper Award )

    E-Print Network [OSTI]

    Bell, John T.

    of Detroit Mercy, Detroit, MI, April 3-4, 1998. ( Best Paper Award ) VIRTUAL REALITY IN CHEMICAL ENGINEERING

  6. EIA - State Electricity Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submit theCovalentLaboratoryDestinationHawaii Electricity Profile 2013

  7. EIA - State Electricity Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submit theCovalentLaboratoryDestinationHawaii Electricity Profile

  8. EIA - State Electricity Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submit theCovalentLaboratoryDestinationHawaiiNevada Electricity Profile

  9. BENDIX SYSTEMS DIVISION ANN AIt 1 o I, MI CH NO. Plan for Operational Contingency

    E-Print Network [OSTI]

    Rathbun, Julie A.

    8/29/66 BENDIX SYSTEMS DIVISION ANN AIt 1 o I, MI CH NO. ATM-396 Plan for Operational Contingency of the operational plans and the system design and to study methods of recovery from partial failure through the use. ATM- 396 RIV.MO. A I I f..r I (I IOperational Contingency Study 2 PAGI OP

  10. New Loops! MiTeGen* 50MicroMountsTM consist of a thin microfabricated

    E-Print Network [OSTI]

    Meagher, Mary

    New Loops! MiTeGen* 50µMicroMountsTM consist of a thin microfabricated polyimide film attached to a solid non-magnetic stainless steel pin. The film is polyimide, which is used in Kapton® tape and is employed for X- ray transparent windows on X-ray beam lines. The film is curved by wrapping polyimide film

  11. 2000 JAPAN-USA Symposium on Flexible Automation July 23-26, 2000, Ann Arbor, MI

    E-Print Network [OSTI]

    Saitou, Kazuhiro "Kazu"

    2000 JAPAN-USA Symposium on Flexible Automation July 23-26, 2000, Ann Arbor, MI 2000JUSFA-US1 OFF-LINE ERROR RECOVERY LOGIC SYNTHESIS IN AUTOMATED ASSEMBLY LINES BY USING GENETIC PROGRAMMING Cem M. Baydar by the experts or automated error recovery logic controllers embedded in the system. The previous work

  12. An HNF4a-miRNA Inflammatory Feedback Circuit Regulates

    E-Print Network [OSTI]

    An HNF4a-miRNA Inflammatory Feedback Circuit Regulates Hepatocellular Oncogenesis Maria, once this circuit is activated, it maintains suppression of HNF4a and sustains oncogenesis. Systemic recapitulate hepatic oncogenesis in various animal models (He et al., 2010). In addition, the inflammatory

  13. AUSTRALIAN. N~TIONAL UNIVE~SITY DEPARTMENTO:miNUCLEAR PFf-y'SICS

    E-Print Network [OSTI]

    Chen, Ying

    AUSTRALIAN. N~TIONAL UNIVE~SITY DEPARTMENTO:miNUCLEAR PFf-y'SICS 14UD TANK OPENING REPORT/iNo. 51 functions for which it provides power. An order was . immediately placed with N.E.C. for 28 perspex bars microamp hours of b.d.p. generation than its predicted lifetime. In preparation for the next opening

  14. MSU CENTER FOR REGIONAL FOOD SYSTEMS 480 WILSON ROAD, EAST LANSING, MI 48824

    E-Print Network [OSTI]

    AN ANNOTATED BIBLIOGRAPHY ON STRUCTURAL RACISM PRESENT IN THE U.S. FOOD SYSTEM JUNE 2015 #12;Michigan State University Center for Regional Food Systems Structural Racism Present in the U.S. Food System 2 AUTHORS Anel on structural racism present in the U.S. food system. East Lansing, MI: MSU Center for Regional Food Systems

  15. Request for Alternative Activity for PLI Credit Last Name First Name M.I.

    E-Print Network [OSTI]

    Connors, Daniel A.

    Request for Alternative Activity for PLI Credit Full Name: Last Name First Name M.I. Email Address information for Coordinator of Program: Requesting Alternate Activity credit for which PLI Track (Choose one): Verification Information Email Address: College of Engineering Student Information Alternate Activity

  16. MI FARM TO SCHOOL GRANTEES 2014-2015 PROGRAM YEAR AND PREVIOUS GRANTEES

    E-Print Network [OSTI]

    MI FARM TO SCHOOL GRANTEES 2014-2015 PROGRAM YEAR AND PREVIOUS GRANTEES FOODSYSTEMS.MSU.EDU 2014-2015 GRANTEES School/ district/ program County Current Grant Years as a grantee A&W Daycare Wayne Planning 1 TO SCHOOL GRANTEES (2011/12 ­ 2013/14) School/ district/ program County Grant Type(s) Grant Years All Aboard

  17. Polyphenol-induced Anti-inflammatory and Cytotoxic Activities in Breast and Colon Cancer: Potential Role of miRNA's in Cell Survival and Inflammation 

    E-Print Network [OSTI]

    Banerjee, Nivedita

    2013-12-11

    growth in athymic BALB/c nude mice with BT474 xenografts. Interactions of Pg with miR-27a- ZBTB10-Sp and miR-155-SHIP-1-PI3K axes and mango miR126/PI3K/AKT axis were identified. In addition, pomegranate and plum polyphenols exerted cytotoxic and anti...

  18. SAE 1983 Transactions, Paper No. 830200, pp. 1.810-1.816 International Congress & Exposition, Detroit, Mi., Feb. 28-March 4, 1983

    E-Print Network [OSTI]

    Radcliffe, Clark J.

    , Detroit, Mi., Feb. 28- March 4, 1983 #12;SAE 1983 Transactions, Paper No. 830200, pp. 1.810-1.816 International Congress & Exposition, Detroit, Mi., Feb. 28- March 4, 1983 #12;SAE 1983 Transactions, Paper No. 830200, pp. 1.810-1.816 International Congress & Exposition, Detroit, Mi., Feb. 28- March 4, 1983 Fig. 2

  19. MiR-18a regulates the proliferation, migration and invasion of human glioblastoma cell by targeting neogenin

    SciTech Connect (OSTI)

    Song, Yichen; Wang, Ping; Zhao, Wei; Yao, Yilong; Liu, Xiaobai; Ma, Jun; Xue, Yixue; Liu, Yunhui

    2014-05-15

    MiR-17-92 cluster has recently been reported as an oncogene in some tumors. However, the association of miR-18a, an important member of this cluster, with glioblastoma remains unknown. Therefore, this study aims to investigate the expression of miR-18a in glioblastoma and its role in biological behavior of U87 and U251 human glioblastoma cell lines. Quantitative RT-PCR results showed that miR-18a was highly expressed in glioblastoma tissues and U87 and U251 cell lines compared with that in human brain tissues and primary normal human astrocytes, and the expression levels were increased along with the rising pathological grades of glioblastoma. Neogenin was identified as the target gene of miR-18a by dual-luciferase reporter assays. RT-PCR and western blot results showed that its expression levels were decreased along with the rising pathological grades of glioblastoma. Inhibition of miR-18a expression was established by transfecting exogenous miR-18a inhibitor into U87 and U251 cells, and its effects on the biological behavior of glioblastoma cells were studied using CCK-8 assay, transwell assay and flow cytometry. Inhibition of miR-18a expression in U87 and U251 cells significantly up-regulated neogenin, and dramatically suppressed the abilities of cell proliferation, migration and invasion, induced cell cycle arrest and promoted cellular apoptosis. Collectively, these results suggest that miR-18a may regulate biological behavior of human glioblastoma cells by targeting neogenin, and miR-18a can serve as a potential target in the treatment of glioblastoma. - Highlights: • MiR-18a was highly expressed in glioblastoma tissues and U87 and U251 cell lines. • Neogenin was identified as the target gene of miR-18a. • Neogenin expressions were decreased along with the rising pathological grades of glioblastoma. • Inhibition of miR-18a suppressed biological behavior of glioma cells by up-regulating neogenin.

  20. Structural Reliability of Bridges Elevated with Steel Pedestals 

    E-Print Network [OSTI]

    Bisadi, Vahid 1980-

    2012-09-19

    Overheight vehicle impact to bridge decks is a major problem in the transportation networks in the United States. An important factor that causes this problem is inadequate vertical clearance of bridges. Using steel pedestals to elevate bridge decks...

  1. Study of catalysis of coal gasification at elevated pressures...

    Office of Scientific and Technical Information (OSTI)

    Study of catalysis of coal gasification at elevated pressures. Evaluation of 20 compounds at 850sup 0C Citation Details In-Document Search Title: Study of catalysis of coal...

  2. miR-7 and miR-218 epigenetically control tumor suppressor genes RASSF1A and Claudin-6 by targeting HoxB3 in breast cancer

    SciTech Connect (OSTI)

    Li, Qiaoyan; Zhu, Fufan; Chen, Puxiang

    2012-07-20

    Highlights: Black-Right-Pointing-Pointer Both miR-7 and miR-218 down-regulates HoxB3 expression by targeting the 3 Prime -UTR of HoxB3 mRNA. Black-Right-Pointing-Pointer A reverse correlation between the levels of endogenous miR-7, miR218 and HoxB3 expression. Black-Right-Pointing-Pointer Epigenetic changes involve in the reactivation of HoxB3. Black-Right-Pointing-Pointer Both miRNAs inhibits the cell cycle and clone formation of breast cancer cells. -- Abstract: Many microRNAs have been implicated as key regulators of cellular growth and differentiation and have been found to dysregulate proliferation in human tumors, including breast cancer. Cancer-linked microRNAs also alter the epigenetic landscape by way of DNA methylation and post-translational modifications of histones. Aberrations in Hox gene expression are important for oncogene or tumor suppressor during abnormal development and malignancy. Although recent studies suggest that HoxB3 is critical in breast cancer, the putative role(s) of microRNAs impinging on HoxB3 is not yet fully understood. In this study, we found that the expression levels of miR-7 and miR-218 were strongly and reversely associated with HoxB3 expression. Stable overexpression of miR-7 and miR-218 was accompanied by reactivation of tumor suppressor genes including RASSF1A and Claudin-6 by means of epigenetic switches in DNA methylation and histone modification, giving rise to inhibition of the cell cycle and clone formation of breast cancer cells. The current study provides a novel link between overexpression of collinear Hox genes and multiple microRNAs in human breast malignancy.

  3. Impact of elevated nitrate on sulfate-reducing bacteria: A comparative study of Desulfovibrio vulgaris

    SciTech Connect (OSTI)

    He, Q.; He, Z.; Joyner, D.C.; Joachimiak, M.; Price, M.N.; Yang, Z.K.; Yen, H.-C. B.; Hemme, C. L.; Chen, W.; Fields, M.; Stahl, D. A.; Keasling, J. D.; Keller, M.; Arkin, A. P.; Hazen, T. C.; Wall, J. D.; Zhou, J.

    2010-07-15

    Sulfate-reducing bacteria have been extensively studied for their potential in heavy-metal bioremediation. However, the occurrence of elevated nitrate in contaminated environments has been shown to inhibit sulfate reduction activity. Although the inhibition has been suggested to result from the competition with nitrate-reducing bacteria, the possibility of direct inhibition of sulfate reducers by elevated nitrate needs to be explored. Using Desulfovibrio vulgaris as a model sulfate-reducing bacterium, functional genomics analysis reveals that osmotic stress contributed to growth inhibition by nitrate as shown by the upregulation of the glycine/betaine transporter genes and the relief of nitrate inhibition by osmoprotectants. The observation that significant growth inhibition was effected by 70 mM NaNO{sub 3} but not by 70 mM NaCl suggests the presence of inhibitory mechanisms in addition to osmotic stress. The differential expression of genes characteristic of nitrite stress responses, such as the hybrid cluster protein gene, under nitrate stress condition further indicates that nitrate stress response by D. vulgaris was linked to components of both osmotic and nitrite stress responses. The involvement of the oxidative stress response pathway, however, might be the result of a more general stress response. Given the low similarities between the response profiles to nitrate and other stresses, less-defined stress response pathways could also be important in nitrate stress, which might involve the shift in energy metabolism. The involvement of nitrite stress response upon exposure to nitrate may provide detoxification mechanisms for nitrite, which is inhibitory to sulfate-reducing bacteria, produced by microbial nitrate reduction as a metabolic intermediate and may enhance the survival of sulfate-reducing bacteria in environments with elevated nitrate level.

  4. A Profile of Profiles: A Meta-analysis of Organizational Commitment Profiles 

    E-Print Network [OSTI]

    Kabins, Adam H

    2013-11-26

    of commitment, this study combined latent profile analysis (LPA) with meta-analysis to examine the antecedents and bases of commitment profiles, utilizing a large archival data set (K = 40; N = 16,052). LPA results revealed five commitment profiles (weak...

  5. "Elevated heat pump" hypothesis for the aerosolmonsoon hydroclimate link: "Grounded" in observations?

    E-Print Network [OSTI]

    Nigam, Sumant

    "Elevated heat pump" hypothesis for the aerosolmonsoon hydroclimate link: "Grounded April 2010; published 18 August 2010. [1] The viability of the elevated heat pump hypothesis, S., and M. Bollasina (2010), "Elevated heat pump" hypothesis for the aerosolmonsoon hydroclimate

  6. State Nuclear Profiles 2010

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effect Photovoltaics -7541C.3X-rays IlluminateState Nuclear Profiles 2010 April 2012

  7. EIA - State Electricity Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submit theCovalentLaboratoryDestinationHawaii Electricity Profile 2013 Table 1. 2013

  8. EIA - State Electricity Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submit theCovalentLaboratoryDestinationHawaii Electricity Profile 2013 Table 1.

  9. EIA - State Electricity Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submit theCovalentLaboratoryDestinationHawaii Electricity Profile 2013 Table

  10. EIA - State Electricity Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submit theCovalentLaboratoryDestinationHawaii Electricity Profile 2013 TableIndiana

  11. EIA - State Electricity Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submit theCovalentLaboratoryDestinationHawaii Electricity Profile 2013Kansas

  12. EIA - State Electricity Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submit theCovalentLaboratoryDestinationHawaii Electricity Profile 2013KansasKentucky

  13. EIA - State Electricity Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submit theCovalentLaboratoryDestinationHawaii Electricity ProfileMaine Electricity

  14. EIA - State Electricity Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submit theCovalentLaboratoryDestinationHawaii Electricity ProfileMaine

  15. EIA - State Electricity Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submit theCovalentLaboratoryDestinationHawaii Electricity ProfileMaineMassachusetts

  16. EIA - State Electricity Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submit theCovalentLaboratoryDestinationHawaiiNevada Electricity Profile 2013 Table 1.

  17. EIA - State Electricity Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submit theCovalentLaboratoryDestinationHawaiiNevada Electricity Profile 2013 Table

  18. EIA - State Electricity Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submit theCovalentLaboratoryDestinationHawaiiNevada Electricity Profile 2013

  19. EIA - State Electricity Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submit theCovalentLaboratoryDestinationHawaiiNevada Electricity Profile 2013Mexico

  20. EIA - State Electricity Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submit theCovalentLaboratoryDestinationHawaiiNevada Electricity ProfileNorth Carolina

  1. EIA - State Electricity Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submit theCovalentLaboratoryDestinationHawaiiNevada Electricity ProfileNorth

  2. EIA - State Electricity Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submit theCovalentLaboratoryDestinationHawaiiNevada Electricity ProfileNorthOhio

  3. EIA - State Electricity Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submit theCovalentLaboratoryDestinationHawaiiNevadaTexas Electricity Profile 2013

  4. EIA - State Electricity Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submit theCovalentLaboratoryDestinationHawaiiNevadaTexas Electricity Profile

  5. EIA - State Electricity Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submit theCovalentLaboratoryDestinationHawaiiNevadaTexas Electricity ProfileUtah

  6. EIA - State Nuclear Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submit theCovalentLaboratoryDestinationHawaiiNevadaTexasWestArkansas Nuclear Profile

  7. Performance of MOV Stem Lubricants at Elevated Temperatures

    SciTech Connect (OSTI)

    DeWall, Kevin George; Nitzel, Michael Everett; Watkins, John Clifford

    2001-07-01

    This paper documents the results of recent tests sponsored by the U. S. Nuclear Regulatory Commission (NRC) and performed by the Idaho National Engineering and Environmental Laboratory (INEEL). These tests address the effectiveness of the lubricant used on the threaded portion of the valve stem, where the stem nut turns on the stem. Recent testing indicates that an elevated temperature environment can lead to significant increases in the friction coefficient at the stem/stem-nut interface. Most valve actuator qualification tests are performed at room temperature. Similarly, in-service tests are run at ambient plant temperatures, usually 70 to 100°F. Since design conditions can lead to valve operating temperatures in the 200 to 300°F range, it is important to know whether a temperature-induced increase in friction at the stem/stem-nut interface will prevent the required operation of critical valves. Lubricant aging is another phenomenon that might have deleterious effects on the thrust output of a valve actuator. Laboratory experience and field experience both indicate that after long periods in elevated temperature environments, the lubricants may lose their lubrication qualities. The scope of the current test program includes testing of five different lubricants on four different valve stems. Pending completion of the testing, results of the tests conducted using two of the four stems are discussed. The test series included collection of baseline data at room temperature, single step temperature tests where the temperature of the test setup was elevated directly to 250°F, and step testing where the temperature was elevated in steps to 130, 190, and 250°F, then returned to 70°F. All greases tested showed evidence of physical change after elevated temperature tests. Except for one particular lubricant, all of the greases tested showed increased coefficients of friction at elevated temperatures. Numerous other preliminary conclusions are presented. Recommendations for future research in the area of aged valve stem lubricant performance at elevated temperatures are also presented.

  8. Deflagration Wave Profiles

    SciTech Connect (OSTI)

    Menikoff, Ralph

    2012-04-03

    Shock initiation in a plastic-bonded explosives (PBX) is due to hot spots. Current reactive burn models are based, at least heuristically, on the ignition and growth concept. The ignition phase occurs when a small localized region of high temperature (or hot spot) burns on a fast time scale. This is followed by a growth phase in which a reactive front spreads out from the hot spot. Propagating reactive fronts are deflagration waves. A key question is the deflagration speed in a PBX compressed and heated by a shock wave that generated the hot spot. Here, the ODEs for a steady deflagration wave profile in a compressible fluid are derived, along with the needed thermodynamic quantities of realistic equations of state corresponding to the reactants and products of a PBX. The properties of the wave profile equations are analyzed and an algorithm is derived for computing the deflagration speed. As an illustrative example, the algorithm is applied to compute the deflagration speed in shock compressed PBX 9501 as a function of shock pressure. The calculated deflagration speed, even at the CJ pressure, is low compared to the detonation speed. The implication of this are briefly discussed.

  9. Does low stomatal conductance or photosynthetic capacity enhance growth at elevated CO2 in Arabidopsis thaliana?

    E-Print Network [OSTI]

    Easlon, Hsien M; Carlisle, Eli; McKay, John K; Bloom, Arnold J

    2015-01-01

    Does low g enhance growth at elevated CO 2 ? To whomEcophysiology and Sustainability Does low g enhance growthat elevated CO 2 ? Does low stomatal conductance or

  10. Fatigue of ceramics at elevated temperatures: Microstructural design for optimal performance

    E-Print Network [OSTI]

    Ritchie, R.O.; Chen, D.; Zhang, X.F.

    2000-01-01

    D IVISION FATIGUE OF CERAMICS AT ELEVATED TEMPERATURES:76SF00098. FATIGUE OF CERAMICS AT ELEVATED TEMPERATURES:silicon carbide (SiC) ceramics offer many advantages,

  11. Project Profile: Carbon Dioxide Shuttling Thermochemical Storage...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Project Profile: Carbon Dioxide Shuttling Thermochemical Storage Using Strontium Carbonate Project Profile: Carbon Dioxide Shuttling Thermochemical Storage Using Strontium...

  12. Project Profile: Thermochemical Storage with Anhydrous Ammonia...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Project Profile: Thermochemical Storage with Anhydrous Ammonia: Optimizing the Synthesis Reactor for Direct Production of Supercritical Steam Project Profile: Thermochemical...

  13. PIANO DI RIQUALIFICAZIONE AMBIENTALE E PAESAGGISTICA DEL TERMOVALORIZZATORE DI DESIO TERMOVALORIZZATORE DI DESIO (MI) BRIANZA ENERGIA E AMBIENTE SPA

    E-Print Network [OSTI]

    Columbia University

    TERMOVALORIZZATORE DI DESIO (MI) ­ BRIANZA ENERGIA E AMBIENTE SPA Impianto di costruito negli anni '70 per lo. · Energia elettrica prodotta: 13.000.000 KWh/anno. LAND S.r.l. Landscape Architecture Nature Development

  14. Profiler Instrumentation Using Metaprogramming Techniques

    E-Print Network [OSTI]

    Gray, Jeffrey G.

    Profiler Instrumentation Using Metaprogramming Techniques Ritu Arora, Yu Sun, Zekai Demirezen, Jeff manipulation) before it enters into the available class pool of an executing application. Javassist [9] (see

  15. W@E Search Profiles

    Broader source: Energy.gov [DOE]

    Search the Women@Energy profiles to learn more about how to get into STEM, inspired by STEM, or find a STEM career.

  16. Search Women@Energy Profiles

    Broader source: Energy.gov [DOE]

    Search the Women@Energy profiles to learn more about how to get into STEM, inspired by STEM, or find a STEM career.

  17. Measurement of Pi-K Ratios from the NuMI Target

    SciTech Connect (OSTI)

    Seun, Sin Man; /Harvard U.

    2007-07-01

    Interactions of protons (p) with the NuMI (Neutrinos at the Main Injector) target are used to create the neutrino beam for the MINOS (Main Injector Neutrino Oscillation Search) Experiment. Using the MIPP (Main Injector Particle Production) experimental apparatus, the production of charged pions and kaons in p+NuMI interactions is studied. The data come from a sample of 2 x 10{sup 6} events obtained by MIPP using the 120 GeV/c proton beam from the Main Injector at Fermi National Accelerator Laboratory in Illinois, USA. Pions and kaons are identified by measurement in a Ring Imaging Cherenkov detector. Presented are measurements of {pi}{sup -}/{pi}{sup +}, K{sup -}/K{sup +}, {pi}{sup +}/K{sup +} and {pi}{sup -}/K{sup -} production ratios in the momentum range p{sub T} < 2 GeV/c transversely and 20 GeV/c < p{sub z} < 90 GeV/c longitudinally. Also provided are detailed comparisons of the MIPP NuMI data with the MIPP Thin Carbon data, the MIPP Monte Carlo simulation and the current MINOS models in the relevant momentum ranges.

  18. Laser profiling of sewer pipes Laser profiling of sewer pipes

    E-Print Network [OSTI]

    Langendoen, Koen

    Laser profiling of sewer pipes #12;#12;Laser profiling of sewer pipes Analysis of concrete egg shaped sewer pipes Walter van der Schoot for the degree of: Master of Science in Civil Engineering Date there is an extensive and well functioning sewer system. Over the years 111.000 kilometres of sewer pipes were

  19. Author's personal copy On stairwell and elevator shaft pressurization for smoke control

    E-Print Network [OSTI]

    Miller, Richard S.

    Author's personal copy On stairwell and elevator shaft pressurization for smoke control in tall Stairwell pressurization Elevator pressurization a b s t r a c t Elevator shaft and stairwell shaft is found to be completely feasible in the absence of elevator shaft pressurization. In contrast, coupled

  20. Steel Energy and Environmental Profile

    SciTech Connect (OSTI)

    none,

    2000-08-01

    Major steelmaking processes (from ironmaking through fabrication and forming) and their associated energy requirements have been profiled in this 2001 report (PDF 582 KB). This profile by Energetics, Inc. also describes the waste streams generated by each process and estimates annual emissions of CO2 and criteria pollutants.

  1. Melting Alpine Glaciers Enrich High-Elevation Lakes with Reactive

    E-Print Network [OSTI]

    Wolfe, Alexander P.

    melt alone (SF lakes) and those fed by both glacial and snowpack meltwaters (GSF lakes). We foundMelting Alpine Glaciers Enrich High-Elevation Lakes with Reactive Nitrogen J A S M I N E E . S A R century in many regions of the world. Resulting changes in glacial runoff not only affect the hydrological

  2. Dramatically elevated rate of mitochondrial substitution in lice (Insecta: Phthiraptera)

    E-Print Network [OSTI]

    Clayton, Dale H.

    mitochondrial DNA, compared to comparable nuclear genes (Brown et al., 1979; Johnson and Clayton, 2000; MiyataDramatically elevated rate of mitochondrial substitution in lice (Insecta: Phthiraptera) Kevin P. Johnson,a,* Robert H. Cruickshank,b Richard J. Adams,c Vincent S. Smith,b Roderic D.M. Page,b and Dale H

  3. 2004-01-2299 Elevated Carbon Dioxide Alters Hydrocarbon

    E-Print Network [OSTI]

    Paré, Paul W.

    2004-01-2299 Elevated Carbon Dioxide Alters Hydrocarbon Emissions and Flavor in Onion P. W. Paré, R of low-molecular-weight hydrocarbons and sulfur derivatives. Odd-chain ketones are emitted from onion-through chambers, volatile hydrocarbons from undamaged plants can be collected under different environmental

  4. Evidence for Stratospheric Downwelling Associated with High-Elevation Topography

    SciTech Connect (OSTI)

    Finkel, R

    2009-01-28

    The continued presence of elevated chlorine-36 in Sierra Nevada streams is commonly interpreted as residual nuclear fallout, but this prolonged storage contradicts accepted hydrologic models, which indicate much less short-term groundwater storage. Our hypothesis is that the chlorine-36 source is stratospheric downwelling during high-intensity storms by measuring beryllium-7 and -10, sodium-22, and chlorium-36 in precipitation, lake, and soil samples. These nuclides are produced in abundance in the stratosphere and, except for chlorine-36, did not occur as nuclear fallout. This project will either substantially change hydrologic models or reveal an unrecognized pathway for stratosphere-troposphere exchange. Either result will have substantial scientific impact. The test of the hypothesis is straightforward. If stratospheric downwelling occurs to the extent indicated by observed Sierran chlorine-36 levels, it should be detectable by elevated levels of beryllium-7 and -10, sodium-22, and chlorine-36 in storm precipitation. Samples will be collected from an established array of sampling locations. If elevated levels of these nuclides are not found, it would cast severe doubt on the hypothesis. In this case, Sierran hydrologic models will have to take into account high levels of long-term groundwater storage. If elevated levels of these nuclides are found in Sierran precipitation, it could only be from stratospheric input, both because nuclear fallout is no longer occurring and because beryllium-7 and -10 and sodium-22 are not produced by atmospheric nuclear tests.

  5. MiR-34a targets GAS1 to promote cell proliferation and inhibit apoptosis in papillary thyroid carcinoma via PI3K/Akt/Bad pathway

    SciTech Connect (OSTI)

    Ma, Yanfei; Qin, Huadong [Department of Fourth Surgery, the Second Affiliated Hospital of Harbin Medical University, 148 Xuefu Road, Nangang District, Harbin 150086 (China)] [Department of Fourth Surgery, the Second Affiliated Hospital of Harbin Medical University, 148 Xuefu Road, Nangang District, Harbin 150086 (China); Cui, Yunfu, E-mail: yfma77@126.com [Department of First Surgery, the Second Affiliated Hospital of Harbin Medical University, 148 Xuefu Road, Nangang District, Harbin 150086 (China)] [Department of First Surgery, the Second Affiliated Hospital of Harbin Medical University, 148 Xuefu Road, Nangang District, Harbin 150086 (China)

    2013-11-29

    Highlights: •MiR-34a is up- and GAS1 is down-regulated in papillary thyroid carcinoma. •GAS1 is a direct target for miR-34a. •MiR-34a promotes PTC cells proliferation and inhibits apoptosis through PI3K/Akt/Bad pathway. -- Abstract: MicroRNAs (miRNAs) are fundamental regulators of cell proliferation, differentiation, and apoptosis, and are implicated in tumorigenesis of many cancers. MiR-34a is best known as a tumor suppressor through repression of growth factors and oncogenes. Growth arrest specific1 (GAS1) protein is a tumor suppressor that inhibits cancer cell proliferation and induces apoptosis through inhibition of RET receptor tyrosine kinase. Both miR-34a and GAS1 are frequently down-regulated in various tumors. However, it has been reported that while GAS1 is down-regulated in papillary thyroid carcinoma (PTC), miR-34a is up-regulated in this specific type of cancer, although their potential roles in PTC tumorigenesis have not been examined to date. A computational search revealed that miR-34a putatively binds to the 3?-UTR of GAS1 gene. In the present study, we confirmed previous findings that miR-34a is up-regulated and GAS1 down-regulated in PTC tissues. Further studies indicated that GAS1 is directly targeted by miR-34a. Overexpression of miR-34a promoted PTC cell proliferation and colony formation and inhibited apoptosis, whereas knockdown of miR-34a showed the opposite effects. Silencing of GAS1 had similar growth-promoting effects as overexpression of miR-34a. Furthermore, miR-34a overexpression led to activation of PI3K/Akt/Bad signaling pathway in PTC cells, and depletion of Akt reversed the pro-growth, anti-apoptotic effects of miR-34a. Taken together, our results demonstrate that miR-34a regulates GAS1 expression to promote proliferation and suppress apoptosis in PTC cells via PI3K/Akt/Bad pathway. MiR-34a functions as an oncogene in PTC.

  6. MiR-145 is downregulated in human ovarian cancer and modulates cell growth and invasion by targeting p70S6K1 and MUC1

    SciTech Connect (OSTI)

    Wu, Huijuan; Xiao, ZhengHua; Wang, Ke; Liu, Wenxin; Hao, Quan

    2013-11-29

    Highlights: •MiR-145 is downregulated in human ovarian cancer. •MiR-145 targets p70S6K1 and MUC1. •p70S6K1 and MUC1 are involved in miR-145 mediated tumor cell growth and cell invasion, respectively. -- Abstract: MicroRNAs (miRNAs) are a family of small non-coding RNA molecules that regulate gene expression at post-transcriptional levels. Previous studies have shown that miR-145 is downregulated in human ovarian cancer; however, the roles of miR-145 in ovarian cancer growth and invasion have not been fully demonstrated. In the present study, Northern blot and qRT-PCR analysis indicate that miR-145 is downregulated in ovarian cancer tissues and cell lines, as well as in serum samples of ovarian cancer, compared to healthy ovarian tissues, cell lines and serum samples. Functional studies suggest that miR-145 overexpression leads to the inhibition of colony formation, cell proliferation, cell growth viability and invasion, and the induction of cell apoptosis. In accordance with the effect of miR-145 on cell growth, miR-145 suppresses tumor growth in vivo. MiR-145 is found to negatively regulate P70S6K1 and MUC1 protein levels by directly targeting their 3?UTRs. Importantly, the overexpression of p70S6K1 and MUC1 can restore the cell colony formation and invasion abilities that are reduced by miR-145, respectively. MiR-145 expression is increased after 5-aza-CdR treatment, and 5-aza-CdR treatment results in the same phenotype as the effect of miR-145 overexpression. Our study suggests that miR-145 modulates ovarian cancer growth and invasion by suppressing p70S6K1 and MUC1, functioning as a tumor suppressor. Moreover, our data imply that miR-145 has potential as a miRNA-based therapeutic target for ovarian cancer.

  7. Laser heterodyne surface profiler

    DOE Patents [OSTI]

    Sommargren, G.E.

    1980-06-16

    A method and apparatus are disclosed for testing the deviation of the face of an object from a flat smooth surface using a beam of coherent light of two plane-polarized components, one of a frequency constantly greater than the other by a fixed amount to produce a difference frequency with a constant phase to be used as a reference, and splitting the beam into its two components. The separate components are directed onto spaced apart points on the face of the object to be tested for smoothness while the face of the object is rotated on an axis normal to one point, thereby passing the other component over a circular track on the face of the object. The two components are recombined after reflection to produce a reflected frequency difference of a phase proportional to the difference in path length of one component reflected from one point to the other component reflected from the other point. The phase of the reflected frequency difference is compared with the reference phase to produce a signal proportional to the deviation of the height of the surface along the circular track with respect to the fixed point at the center, thereby to produce a signal that is plotted as a profile of the surface along the circular track. The phase detector includes a quarter-wave plate to convert the components of the reference beam into circularly polarized components, a half-wave plate to shift the phase of the circularly polarized components, and a polarizer to produce a signal of a shifted phase for comparison with the phase of the frequency difference of the reflected components detected through a second polarizer. Rotation of the half-wave plate can be used for phase adjustment over a full 360/sup 0/ range.

  8. JOBAID-ACCESSING AND MODIFYING TALENT PROFILE

    Broader source: Energy.gov [DOE]

    The purpose of this job aid is to guide users through the step-by-step process of accessing their talent profiles, adding information to their profiles, and editing existing talent profile...

  9. AUTOMATIC PROGRAM TIMING PROFILES WITH FTN4

    E-Print Network [OSTI]

    Friedman, Richard.

    2010-01-01

    September 22-25, 1980 AUTOMATIC PROGRAM TIMING PROFILES WITHW-7405-ENG-48 LBL-1l290 Automatic Program Timing ProfilesW-1405-ENG-48 LBL-11290 Automatic Program Timing Profiles

  10. Testing CPT conservation using the NuMI neutrino beam with the MINOS experiment

    SciTech Connect (OSTI)

    Auty, David John; /Sussex U.

    2010-05-01

    The MINOS experiment was designed to measure neutrino oscillation parameters with muon neutrinos. It achieves this by measuring the neutrino energy spectrum and flavor composition of the man-made NuMI neutrino beam 1km after the beam is formed and again after 735 km. By comparing the two spectra it is possible to measure the oscillation parameters. The NuMI beam is made up of 7.0% {bar {nu}}{sub {mu}}, which can be separated from the {nu}{sub {mu}} because the MINOS detectors are magnetized. This makes it possible to study {bar {nu}}{sub {mu}} oscillations separately from those of muon neutrinos, and thereby test CPT invariance in the neutrino sector by determining the {bar {nu}}{sub {mu}} oscillation parameters and comparing them with those for {nu}{sub {mu}}, although any unknown physics of the antineutrino would appear as a difference in oscillation parameters. Such a test has not been performed with beam {bar {nu}}{sub {mu}} before. It is also possible to produce an almost pure {bar {nu}}{sub {mu}} beam by reversing the current through the magnetic focusing horns of the NuMI beamline, thereby focusing negatively, instead of positively charged particles. This thesis describes the analysis of the 7% {bar {nu}}{sub {mu}} component of the forward horn current NuMI beam. The {bar {nu}}{sub {mu}} of a data sample of 3.2 x 10{sup 20} protons on target analysis found 42 events, compared to a CPT conserving prediction of 58.3{sub -7.6}{sup +7.6}(stat.){sub -3.6}{sup +3.6}(syst.) events. This corresponds to a 1.9 {sigma} deficit, and a best fit value of {Delta}{bar m}{sub 32}{sup 2} = 18 x 10{sup -3} eV{sup 2} and sin{sup 2} 2{bar {theta}}{sub 23} = 0.55. This thesis focuses particularly on the selection of {bar {nu}}{sub {mu}} events, and investigates possible improvements of the selection algorithm. From this a different selector was chosen, which corroborated the findings of the original selector. The thesis also investigates how the systematic errors affect the precision of {Delta}{bar m}{sub 32}{sup 2} and sin{sup 2} 2{bar {theta}}{sub 23}. Furthermore, it describes a study to determine the gains of the PMTs via the single-photoelectron spectrum. The results were used as a crosscheck of the gains determined at higher intensities by an LED-based light-injection system.

  11. AMENDMENT OF SOLICITATION/MODIFICATlON OF CONTRACT MI54 I See Block 16C I

    National Nuclear Security Administration (NNSA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal GasAdministration Medal01 Sandia National 1 PAGE 1 OF2 AMENDMENTNLUF1 82 Se elBabcockMI54

  12. Adrenaline promotes cell proliferation and increases chemoresistance in colon cancer HT29 cells through induction of miR-155

    SciTech Connect (OSTI)

    Pu, Jun [Department of General Surgery, Tangdu Hospital of the Fourth Military Medical University, Xi'an 710038 (China)] [Department of General Surgery, Tangdu Hospital of the Fourth Military Medical University, Xi'an 710038 (China); Bai, Danna [Department of Cardiology, 323 Hospital of PLA, Xi'an 710054 (China)] [Department of Cardiology, 323 Hospital of PLA, Xi'an 710054 (China); Yang, Xia [Department of Teaching and Medical Administration, Tangdu Hospital of the Fourth Military Medical University, Xi'an 710038 (China)] [Department of Teaching and Medical Administration, Tangdu Hospital of the Fourth Military Medical University, Xi'an 710038 (China); Lu, Xiaozhao [Department of Nephrology, The 323 Hospital of PLA, Xi'an 710054 (China)] [Department of Nephrology, The 323 Hospital of PLA, Xi'an 710054 (China); Xu, Lijuan, E-mail: 13609296272@163.com [Department of Nephrology, The 323 Hospital of PLA, Xi'an 710054 (China)] [Department of Nephrology, The 323 Hospital of PLA, Xi'an 710054 (China); Lu, Jianguo, E-mail: lujianguo029@yahoo.com.cn [Department of General Surgery, Tangdu Hospital of the Fourth Military Medical University, Xi'an 710038 (China)] [Department of General Surgery, Tangdu Hospital of the Fourth Military Medical University, Xi'an 710038 (China)

    2012-11-16

    Highlights: Black-Right-Pointing-Pointer Adrenaline increases colon cancer cell proliferation and its resistance to cisplatin. Black-Right-Pointing-Pointer Adrenaline activates NF{kappa}B in a dose dependent manner. Black-Right-Pointing-Pointer NF{kappa}B-miR-155 pathway contributes to cell proliferation and resistance to cisplatin. -- Abstract: Recently, catecholamines have been described as being involved in the regulation of cancer genesis and progression. Here, we reported that adrenaline increased the cell proliferation and decreased the cisplatin induced apoptosis in HT29 cells. Further study found that adrenaline increased miR-155 expression in an NF{kappa}B dependent manner. HT29 cells overexpressing miR-155 had a higher cell growth rate and more resistance to cisplatin induced apoptosis. In contrast, HT29 cells overexpressing miR-155 inhibitor displayed decreased cell proliferation and sensitivity to cisplatin induced cell death. In summary, our study here revealed that adrenaline-NF{kappa}B-miR-155 pathway at least partially contributes to the psychological stress induced proliferation and chemoresistance in HT29 cells, shedding light on increasing the therapeutic strategies of cancer chemotherapy.

  13. Trends for Outer Disk Profiles

    E-Print Network [OSTI]

    Peter Erwin; Michael Pohlen; Leonel Gutierrez; John E. Beckman

    2007-12-10

    The surface-brightness profiles of galaxy disks fall into three main classes, based on whether they are simple exponentials (Type I), bend down at large radii (Type II, "truncations") or bend up at large radii (Type III, "antitruncations"). Here, we discuss how the frequency of these different profiles depends on Hubble type, environment, and the presence or absence of bars; these trends may herald important new tests for disk formation models.

  14. Trends for Outer Disk Profiles

    E-Print Network [OSTI]

    Erwin, Peter; Gutíerrez, Leonel; Beckman, John E

    2007-01-01

    The surface-brightness profiles of galaxy disks fall into three main classes, based on whether they are simple exponentials (Type I), bend down at large radii (Type II, "truncations") or bend up at large radii (Type III, "antitruncations"). Here, we discuss how the frequency of these different profiles depends on Hubble type, environment, and the presence or absence of bars; these trends may herald important new tests for disk formation models.

  15. Corrosion resistant coatings suitable for elevated temperature application

    DOE Patents [OSTI]

    Chan, Kwai S. (San Antonio, TX); Cheruvu, Narayana Sastry (San Antonio, TX); Liang, Wuwei (Austin, TX)

    2012-07-31

    The present invention relates to corrosion resistance coatings suitable for elevated temperature applications, which employ compositions of iron (Fe), chromium (Cr), nickel (Ni) and/or aluminum (Al). The compositions may be configured to regulate the diffusion of metals between a coating and a substrate, which may then influence coating performance, via the formation of an inter-diffusion barrier layer. The inter-diffusion barrier layer may comprise a face-centered cubic phase.

  16. Systems simulation of oil additives to grain at terminal elevators 

    E-Print Network [OSTI]

    Goforth, Kerry James

    1985-01-01

    Negligible colorless, odorless stable, inert From: McIlveen, 1984 12 Previous Research Dust suppression characteristics of mineral oil have been evaluated at the United States Grain Marketing Research Laboratory in Manhatten, Kansas. Lai et al. (1981... and are not separated out by normal grain inspection procedures. Foreign matter reductions of up to 1. 5 percent have been reported in informal experiments (Hegadorn, 1984). Country elevators that have no dust collection systems are realizing savings from oil...

  17. Does elevated CO2 alter silica uptake in trees?

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Fulweiler, Robinson W.; Maguire, Timothy J.; Carey, Joanna C.; Finzi, Adrien C.

    2015-01-13

    Human activities have greatly altered global carbon (C) and Nitrogen (N) cycling. In fact, atmospheric concentrations of carbon dioxide (CO2) have increased 40% over the last century and the amount of N cycling in the biosphere has more than doubled. In an effort to understand how plants will respond to continued global CO2 fertilization, longterm free-air CO2 enrichment experiments have been conducted at sites around the globe. Here we examine how atmospheric CO2 enrichment and N fertilization affects the uptake of silicon (Si) in the Duke Forest, North Carolina, a stand dominated by Pinus taeda (loblolly pine), and five hardwoodmore »species. Specifically, we measured foliar biogenic silica concentrations in five deciduous and one coniferous species across three treatments: CO2 enrichment, N enrichment, and N and CO2 enrichment. We found no consistent trends in foliar Si concentration under elevated CO2, N fertilization, or combined elevated CO2 and N fertilization. However, two-thirds of the tree species studied here have Si foliar concentrations greater than well-known Si accumulators, such as grasses. Based on net primary production values and aboveground Si concentrations in these trees, we calculated forest Si uptake rates under control and elevated CO2 concentrations. Due largely to increased primary production, elevated CO2 enhanced the magnitude of Si uptake between 20 and 26%, likely intensifying the terrestrial silica pump. This uptake of Si by forests has important implications for Si export from terrestrial systems, with the potential to impact C sequestration and higher trophic levels in downstream ecosystems.« less

  18. Project Profile: Regenerative Carbonate-Based Thermochemical...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Project Profile: Regenerative Carbonate-Based Thermochemical Energy Storage System for Concentrating Solar Power Project Profile: Regenerative Carbonate-Based Thermochemical Energy...

  19. Profiles in Leadership: Christopher Smith, Assistant Secretary...

    Energy Savers [EERE]

    Profiles in Leadership: Christopher Smith, Assistant Secretary for Fossil Energy Profiles in Leadership: Christopher Smith, Assistant Secretary for Fossil Energy July 15, 2015 -...

  20. Approximate Stokes Drift Profiles in Deep Water

    E-Print Network [OSTI]

    Breivik, Øyvind; Bidlot, Jean-Raymond

    2014-01-01

    A deep-water approximation to the Stokes drift velocity profile is explored as an alternative to the monochromatic profile. The alternative profile investigated relies on the same two quantities required for the monochromatic profile, viz the Stokes transport and the surface Stokes drift velocity. Comparisons with parametric spectra and profiles under wave spectra from the ERA-Interim reanalysis and buoy observations reveal much better agreement than the monochromatic profile even for complex sea states. That the profile gives a closer match and a more correct shear has implications for ocean circulation models since the Coriolis-Stokes force depends on the magnitude and direction of the Stokes drift profile and Langmuir turbulence parameterizations depend sensitively on the shear of the profile. The alternative profile comes at no added numerical cost compared to the monochromatic profile.

  1. Assessment of radiological releases from the NuMI facility during MINOS and NOvA operations

    SciTech Connect (OSTI)

    Martens, Mike; /Fermilab

    2007-04-01

    This report makes projections of the radiological releases from the NuMI facility during operations for the MINOS and NO ?A experiments. It includes an estimate of the radionuclide levels released into the atmosphere and the estimated tritium and sodium-22 concentrations in the NuMI sump water and Fermilab pond system. The analysis was performed for NuMI operations with a beam power on target increased from the present 400 kW design up to a possible 1500 kW with future upgrades. The total number of protons on target was assumed to be 18 x 10{sup 20} after the completion of MINOS and 78 x 10{sup 20} after the completion of NO ?A.

  2. The MiMeS Survey of Magnetism in Massive Stars: Introduction and overview

    E-Print Network [OSTI]

    Wade, G A; Alecian, E; Grunhut, J H; Petit, V; de Batz, B; Bohlender, D A; Cohen, D H; Henrichs, H F; Kochukhov, O; Landstreet, J D; Manset, N; Martins, F; Mathis, S; Oksala, M E; Owocki, S P; Rivinius, Th; Shultz, M E; Sundqvist, J O; Townsend, R H D; ud-Doula, A; Bouret, J -C; Braithwaite, J; Briquet, M; Carciofi, A C; David-Uraz, A; Folsom, C P; Fullerton, A W; Leroy, B; Marcolino, W L F; Moffat, A F J; Nazé, Y; Aurière, M; Bagnulo, S; Bailey, J D; Barbá, R H; Blazère, A; Böhm, T; Catala, C; Donati, J -F; Ferrario, L; Harrington, D; Howarth, I D; Ignace, R; Kaper, L; Lüftinger, T; Prinja, R; Vink, J S; Weiss, W W; Yakunin, I

    2015-01-01

    The MiMeS project is a large-scale, high resolution, sensitive spectropolarimetric investigation of the magnetic properties of O and early B type stars. Initiated in 2008 and completed in 2013, the project was supported by 3 Large Program allocations, as well as various programs initiated by independent PIs and archival resources. Ultimately, over 4800 circularly polarized spectra of 560 O and B stars were collected with the instruments ESPaDOnS at the Canada-France-Hawaii Telescope, Narval at the T\\'elescope Bernard Lyot, and HARPSpol at the European Southern Observatory La Silla 3.6m telescope, making MiMeS by far the largest systematic investigation of massive star magnetism ever undertaken. In this paper, the first in a series reporting the general results of the survey, we introduce the scientific motivation and goals, describe the sample of targets, review the instrumentation and observational techniques used, explain the exposure time calculation designed to provide sensitivity to surface dipole fields...

  3. Upgrade of the Minos+ Experiment Data Acquisition for the High Energy NuMI Beam Run

    E-Print Network [OSTI]

    William Badgett; Steve R. Hahn; Donatella Torretta; Jerry Meier; Jeffrey Gunderson; Denise Osterholm; David Saranen

    2015-06-06

    The Minos+ experiment is an extension of the Minos experiment at a higher energy and more intense neutrino beam, with the data collection having begun in the fall of 2013. The neutrino beam is provided by the Neutrinos from the Main Injector (NuMI) beam-line at Fermi National Accelerator Laboratory (Fermilab). The detector apparatus consists of two main detectors, one underground at Fermilab and the other in Soudan, Minnesota with the purpose of studying neutrino oscillations at a base line of 735 km. The original data acquisition system has been running for several years collecting data from NuMI, but with the extended run from 2013, parts of the system needed to be replaced due to obsolescence, reliability problems, and data throughput limitations. Specifically, we have replaced the front-end readout controllers, event builder, and data acquisition computing and trigger processing farms with modern, modular and reliable devices with few single points of failure. The new system is based on gigabit Ethernet TCP/IP communication to implement the event building and concatenation of data from many front-end VME readout crates. The simplicity and partitionability of the new system greatly eases the debugging and diagnosing process. The new system improves throughput by about a factor of three compared to the old system, up to 800 megabits per second, and has proven robust and reliable in the current run.

  4. Soot surface temperature measurements in pure and diluted flames at atmospheric and elevated pressures

    SciTech Connect (OSTI)

    Berry Yelverton, T.L.; Roberts, W.L. [Department of Mechanical and Aerospace Engineering, Campus Box 7910, North Carolina State University, 3211 Broughton Hall, Raleigh, NC 27695 (United States)

    2008-10-15

    Soot surface temperature was measured in laminar jet diffusion flames at atmospheric and elevated pressures. The soot surface temperature was measured in flames at one, two, four, and eight atmospheres with both pure and diluted (using helium, argon, nitrogen, or carbon dioxide individually) ethylene fuels with a calibrated two-color soot pyrometry technique. These two dimensional temperature profiles of the soot aid in the analysis and understanding of soot production, leading to possible methods for reducing soot emission. Each flame investigated was at its smoke point, i.e., at the fuel flow rate where the overall soot production and oxidation rates are equal. The smoke point was chosen because it was desirable to have similar soot loadings for each flame. A second set of measurements were also taken where the fuel flow rate was held constant to compare with earlier work. These measurements show that overall flame temperature decreases with increasing pressure, with increasing pressure the position of peak temperature shifts to the tip of the flame, and the temperatures measured were approximately 10% lower than those calculated assuming equilibrium and neglecting radiation. (author)

  5. The experience and image of American elevated railways : rapid transit infrastructure in the urban consciousness

    E-Print Network [OSTI]

    Hansen, Gordon Benedict

    2009-01-01

    At the turn of the twentieth century, elevated railways were built out of a practical need to literally "elevate" traffic above the street. In most cases, these lines served two distinct purposes. They served existing ...

  6. Estimated impacts of climate warming on California’s high-elevation hydropower

    E-Print Network [OSTI]

    Madani, Kaveh; Lund, Jay R.

    2010-01-01

    on high elevation hydropower generation in California’sCalifornia’s high-elevation hydropower Kaveh Madani · Jay R.Abstract California’s hydropower system is composed of high

  7. Glass Ceiling or Glass Elevator: Are Voters Biased in Favor of Women Candidates in California Elections?

    E-Print Network [OSTI]

    Abney, Ronni Marie; Peterson, Rolfe Daus

    2011-01-01

    10.2202/1944-4370.1103 Abney and Peterson: Glass Ceilingor Glass Elevator Table 7A. Positive Gender Bias ModelAbney and Peterson: Glass Ceiling or Glass Elevator Huddy,

  8. Estimated impacts of climate warming on California’s high-elevation hydropower

    E-Print Network [OSTI]

    Madani, Kaveh; Lund, Jay R.

    2010-01-01

    Cubed M (2005) Potential changes in hydropower productionpotential effects of climate warming on high-elevation hydropower

  9. Curcumin promotes apoptosis in A549/DDP multidrug-resistant human lung adenocarcinoma cells through an miRNA signaling pathway

    SciTech Connect (OSTI)

    Zhang, Jian, E-mail: zhangjian197011@yahoo.com [Department of Respiratory Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032 (China)] [Department of Respiratory Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032 (China); Zhang, Tao [Department of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038 (China)] [Department of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038 (China); Ti, Xinyu; Shi, Jieran; Wu, Changgui; Ren, Xinling [Department of Respiratory Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032 (China)] [Department of Respiratory Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032 (China); Yin, Hong, E-mail: yinnhong@yahoo.com [The Medical Image Center, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032 (China)] [The Medical Image Center, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032 (China)

    2010-08-13

    Research highlights: {yields} Curcumin had anti-cancer effects on A549/DDP multidrug-resistant human lung adenocarcinoma cells {yields} Curcumin promotes apoptosis in A549/DDP cells through a miRNA signaling pathway {yields} Curcumin induces A549/DDP cell apoptosis by downregulating miR-186* {yields} miR-186* may serve as a potential gene therapy target for refractory lung cancer that is sensitive to curcumin -- Abstract: Curcumin extracted from the rhizomes of Curcuma longa L. has been shown to have inhibitory effects on cancers through its anti-proliferative and pro-apoptotic activities. Emerging evidence demonstrates that curcumin can overcome drug resistance to classical chemotherapies. Thus, the mechanisms underlying the anti-tumor activities of curcumin require further study. In our study, we first demonstrated that curcumin had anti-cancer effects on A549/DDP multidrug-resistant human lung adenocarcinoma cells. Further studies showed that curcumin altered miRNA expression; in particular, significantly downregulated the expression of miR-186* in A549/DDP. In addition, transfection of cells with a miR-186* inhibitor promoted A549/DDP apoptosis, and overexpression of miR-186* significantly inhibited curcumin-induced apoptosis in A549/DDP cells. These observations suggest that miR-186* may serve as a potential gene therapy target for refractory lung cancer that is sensitive to curcumin.

  10. Quality Controlled Radiosonde Profile from MC3E

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Toto, Tami; Jensen, Michael

    The sonde-adjust VAP produces data that corrects documented biases in radiosonde humidity measurements. Unique fields contained within this datastream include smoothed original relative humidity, dry bias corrected relative humidity, and final corrected relative humidity. The smoothed RH field refines the relative humidity from integers - the resolution of the instrument - to fractions of a percent. This profile is then used to calculate the dry bias corrected field. The final correction fixes a time-lag problem and uses the dry-bias field as input into the algorithm. In addition to dry bias, solar heating is another correction that is encompassed in the final corrected relative humidity field. Additional corrections were made to soundings at the extended facility sites (S0*) as necessary: Corrected erroneous surface elevation (and up through rest of height of sounding), for S03, S04 and S05. Corrected erroneous surface pressure at Chanute (S02).

  11. Quality Controlled Radiosonde Profile from MC3E

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Toto, Tami; Jensen, Michael

    2014-11-13

    The sonde-adjust VAP produces data that corrects documented biases in radiosonde humidity measurements. Unique fields contained within this datastream include smoothed original relative humidity, dry bias corrected relative humidity, and final corrected relative humidity. The smoothed RH field refines the relative humidity from integers - the resolution of the instrument - to fractions of a percent. This profile is then used to calculate the dry bias corrected field. The final correction fixes a time-lag problem and uses the dry-bias field as input into the algorithm. In addition to dry bias, solar heating is another correction that is encompassed in the final corrected relative humidity field. Additional corrections were made to soundings at the extended facility sites (S0*) as necessary: Corrected erroneous surface elevation (and up through rest of height of sounding), for S03, S04 and S05. Corrected erroneous surface pressure at Chanute (S02).

  12. Three-dimensional scapulothoracic motion during active and passive arm elevation

    E-Print Network [OSTI]

    Karduna, Andrew

    Three-dimensional scapulothoracic motion during active and passive arm elevation D. David Ebaugh a (active versus passive arm elevation) on three-dimensional scapulothoracic motion. Methods. Twenty during active and passive arm elevation. Muscle activity was recorded from surface electrodes over

  13. Effects of elevated CO2 , nitrogen deposition, and decreased species diversity on foliar fungal plant disease

    E-Print Network [OSTI]

    Thomas, David D.

    Effects of elevated CO2 , nitrogen deposition, and decreased species diversity on foliar fungal Three components of global change, elevated CO2 , nitrogen addition, and decreased plant species increasing more in pathogen load. Elevated CO2 increased pathogen load of C3 grasses, perhaps by decreasing

  14. miR-206 is down-regulated in breast cancer and inhibits cell proliferation through the up-regulation of cyclinD2

    SciTech Connect (OSTI)

    Zhou, Jing; Tian, Ye; Li, Juan; Lu, Binbin; Sun, Ming; Zou, Yanfen; Kong, Rong; Luo, Yanhong; Shi, Yongguo; Wang, Keming; Ji, Guozhong

    2013-04-05

    Highlights: ? miR-206 was downexpressed in tumor samples compared with matched normal samples. ? Enhanced expression of miR-206 could inhibit breast cancer growth in vitro. ? Luciferase confirmed miR-206 functions as an anti-oncogene by targeting cyclinD2. ? A reverse correlation between miR-206 and cyclinD2 in breast cancer was found. -- Abstract: MicroRNAs act as important gene regulators in human genomes, and their aberrant expression is linked to many malignancies. Aberrant expression of miR-206 has been frequently reported in cancer studies; however, the role and mechanism of its function in breast cancer remains unclear. Quantitative real-time PCR was performed to detect the relative expression levels of miR-206 in breast cancer and normal breast tissues. Lower expression of miR-206 in breast cancer tissues was associated with larger tumour size and a more advanced clinical stage. Further in vitro observations showed that the enforced expression of miR-206 in MCF-7 breast cancer cells inhibited cell growth by blocking the G1/S transition and suppressed cell proliferation and colony formation, implying that miR-206 functions as a tumour suppressor in the progression of breast cancer. Interestingly, Luciferase assays first revealed that miR-206 inhibited cyclinD2 expression by targeting two binding sites in the 3?-untranslated region of cyclinD2 mRNA. qRT-PCR and Western blot assays verified that miR-206 reduced cyclinD2 expression at both the mRNA and protein levels. A reverse correlation between miR-206 and cyclinD2 expression was noted in breast cancer tissues. Altogether, our results identify a crucial tumour suppressive role of miR-206 in the progression of breast cancer, at least partly via up-regulation of the expression of cyclinD2, and suggest that miR-206 might be a candidate prognostic predictor or an anticancer therapeutic target for breast cancer patients.

  15. On Boiling of Crude Oil under Elevated Pressure

    E-Print Network [OSTI]

    Pimenova, Anastasiya V

    2015-01-01

    We construct a thermodynamic model for theoretical calculation of the boiling process of multicomponent mixtures of hydrocarbons (e.g., crude oil). The model governs kinetics of the mixture composition in the course of the distillation process along with the boiling temperature increase. The model heavily relies on the theory of dilute solutions of gases in liquids. Importantly, our results are applicable for modelling the process under elevated pressure (while the empiric models for oil cracking are not scalable to the case of extreme pressure), such as in an oil field heated by lava intrusions.

  16. On Boiling of Crude Oil under Elevated Pressure

    E-Print Network [OSTI]

    Anastasiya V. Pimenova; Denis S. Goldobin

    2015-10-08

    We construct a thermodynamic model for theoretical calculation of the boiling process of multicomponent mixtures of hydrocarbons (e.g., crude oil). The model governs kinetics of the mixture composition in the course of the distillation process along with the boiling temperature increase. The model heavily relies on the theory of dilute solutions of gases in liquids. Importantly, our results are applicable for modelling the process under elevated pressure (while the empiric models for oil cracking are not scalable to the case of extreme pressure), such as in an oil field heated by lava intrusions.

  17. PROFILE SHAPE PARAMETERIZATION OF JET ELECTRON TEMPERATURE AND DENSITY PROFILES

    E-Print Network [OSTI]

    of heating power, with ion cyclotron resonant heating producing a more peaked profile than neutral beam injection. Given the heating type dependence, the L­mode temperature shape is nearly independent , increases. The line average L­mode temperature scales as B :96 t (Power per particle) :385 . The L

  18. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne: OFFICE OF STUDENT FINANCIAL AID · The Welcome Center · P. O. Box 2340 · 42 West Warren · Detroit, MI

  19. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · www FINANCIAL AID · The Welcome Center · P. O. Box 2340 · 42 West Warren · Detroit, MI 48202-0340 If this form

  20. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · www OF STUDENT FINANCIAL AID · The Welcome Center · P. O. Box 2340 · 42 West Warren · Detroit, MI 48202-0340 3

  1. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne · Detroit, MI 48202-0340 Student's First Name 9-digit WSU Student ID # Student's Last Name Phone Number 3

  2. NUEX16 Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne FINANCIAL AID · The Welcome Center · P. O. Box 2340 · 42 West Warren · Detroit, MI 48202-0340 Student

  3. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · www · Detroit, MI 48202-0340 If this form is required it will be listed in Pipeline, under "My Requirements" 3

  4. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · www Warren · Detroit, MI 48202-0340 If this form is required it will be listed in Pipeline, under "My

  5. Manuscript was received April 15, 2007. Irina Hossain is with the Department of Electrical and Computer Engineering, Wayne State University, Detroit, MI. Phone: 651-815-5828; Fax: 651-

    E-Print Network [OSTI]

    Mahmud, Syed Masud

    and Computer Engineering, Wayne State University, Detroit, MI. Phone: 651-815-5828; Fax: 651- 305-4549; e State University, Detroit, MI. Phone: 313-577-3855; Fax: 313-577-5845; e-mail: smahmud

  6. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne Warren · Detroit, MI 48202-0340 Student's First Name 9-digit WSU Student ID # Student's Last Name Phone

  7. CTFS16 Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne · Detroit, MI 48202-0340 3/2015 Student's First Name 9-digit WSU Student ID # Student's Last Name Phone

  8. VRHS14 Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · www: OFFICE OF STUDENT FINANCIAL AID · The Welcome Center · P. O. Box 2340 · 42 West Warren · Detroit, MI

  9. Network Modeling Identifies Molecular Functions Targeted by miR-204 to Suppress Head and Neck Tumor

    E-Print Network [OSTI]

    Gerstein, Mark

    Network Modeling Identifies Molecular Functions Targeted by miR-204 to Suppress Head and Neck Tumor targets predicted by sequence-alignment databases and the relative low accuracy of such predictions which with tumor progression in squamous cell carcinoma of the head and neck (HNSCC). We further demonstrate

  10. Corrosion mechanisms of low level vitrified radioactive waste in a loamy soil M.I. Ojovan1

    E-Print Network [OSTI]

    Sheffield, University of

    Corrosion mechanisms of low level vitrified radioactive waste in a loamy soil M.I. Ojovan1 , W-sodium content radioactive waste borosilicate glass buried in a loamy soil (glass K-26) and in an open testing. This mechanism is likely to remain dominant until the decay of 137 Cs in the glass is below exemption levels

  11. A trans-homologue interaction between reciprocally imprinted miR-127 and Rtl1 regulates placenta development

    E-Print Network [OSTI]

    Ito, Mitsuteru; Sferruzzi-Perri, Amanda N.; Edwards, Carol A.; Adalsteinsson, Bjorn T.; Allen, Sarah E.; Loo, Tsui-Han; Kitazawa, Moe; Kaneko-Ishino, Tomoko; Ishino, Fumitoshi; Stewart, Colin L.; Ferguson-Smith, Anne C.

    2015-07-02

    ability of small molecules like oxygen to transfer by passive diffusion from mother to fetus (Laga et al., 1973). The TDC and SDC values of the mutant placentae indicate that ?miR-127 mice have a higher diffusive capacity than WTs and conversely...

  12. THE DARK SIDE OF SECURITY BY OBSCURITY and Cloning MiFare Classic Rail and Building Passes, Anywhere, Anytime

    E-Print Network [OSTI]

    International Association for Cryptologic Research (IACR)

    , Anywhere, Anytime Nicolas T. Courtois University College London, Computer Science, Gower street, WC1E 6BT, London, UK Keywords: Access control, RFID, contactless smart cards, MiFare Classic, London Oyster card- wide and in public transportation. For more than 10 years the specification of these cards was kept

  13. A note on tsunami amplitudes above submarine slides and slumps M.I. Todorovska*, A. Hayir1

    E-Print Network [OSTI]

    Southern California, University of

    A note on tsunami amplitudes above submarine slides and slumps M.I. Todorovska*, A. Hayir1 , M 2531, Los Angeles, CA 90089-2531, USA Accepted 27 October 2001 Abstract Tsunami generated by submarine functions. Tsunami waveforms for these models are computed using linearized shallow water theory

  14. The PEANUT experiment in the NuMI beam at Fermilab

    SciTech Connect (OSTI)

    Russo, A. [Dipartimento di Scienze Fisiche, Universita Federico II di Napoli, 80125 Napoli (Italy)

    2010-03-30

    The PEANUT experiment was designed to study neutrino interactions in the few GeV range using the NuMI beam at Fermilab. The detector uses a hybrid technique, being made of nuclear emulsions and scintillator trackers. Emulsion films act as a tracking device and they are interleaved with lead plates used as neutrino targets. The detector is designed to reconstruct the topology of neutrino interactions at the single particle level. We present here the full reconstruction and analysis of a sample of 147 neutrino interactions that occurred in the PEANUT detector and the measurement of the quasielastic, resonance and deep-inelastic contributions to the total charged-current cross section. This technique could be applied for the beam monitoring at future neutrino facilities.

  15. Chief Technology Officer Opportunity Profile

    E-Print Network [OSTI]

    Mazzotti, Frank

    Chief Technology Officer Opportunity Profile #12;CHIEF TECHNOLOGY OFFICER Date: 01/23/2015 Prepared for the position and to give a deeper understanding of the role of Chief Technology Officer. We have also included: POSITION ANNOUNCEMENT TAB V: THE REGION TAB I: POSITION ANNOUNCEMENT #12;Chief Technology Officer

  16. MODELING OF CHANGING ELECTRODE PROFILES

    SciTech Connect (OSTI)

    Prentice, Geoffrey Allen

    1980-12-01

    A model for simulating the transient behavior of solid electrodes undergoing deposition or dissolution has been developed. The model accounts for ohmic drop, charge transfer overpotential, and mass transport limitations. The finite difference method, coupled with successive overrelaxation, was used as the basis of the solution technique. An algorithm was devised to overcome the computational instabilities associated with the calculations of the secondary and tertiary current distributions. Simulations were performed on several model electrode profiles: the sinusoid, the rounded corner, and the notch. Quantitative copper deposition data were obtained in a contoured rotating cylinder system, Sinusoidal cross-sections, machined on stainless steel cylinders, were used as model geometries, Kinetic parameters for use in the simulation were determined from polarization curves obtained on copper rotating cylinders, These parameters, along with other physical property and geometric data, were incorporated in simulations of growing sinusoidal profiles. The copper distributions on the sinusoidal cross-sections were measured and found to compare favorably with the simulated results. At low Wagner numbers the formation of a slight depression at the profile peak was predicted by the simulation and observed on the profile. At higher Wagner numbers, the simulated and experimental results showed that the formation of a depression was suppressed. This phenomenon was shown to result from the competition between ohmic drop and electrode curvature.

  17. Energy Consumption Profile for Energy

    E-Print Network [OSTI]

    Langendoen, Koen

    ...................................................................................318 12.2.1 Motivations for Energy Harvesting...............................................319 12 the example of a "smart application'' assisted by a decision engine that transforms itself into an "energy317 Chapter 12 Energy Consumption Profile for Energy Harvested WSNs T. V. Prabhakar, R Venkatesha

  18. Country Energy Profile, South Africa

    SciTech Connect (OSTI)

    1995-08-01

    This country energy profile provides energy and economic information about South Africa. Areas covered include: Economics, demographics, and environment; Energy situation; Energy structure; Energy investment opportunities; Department of Energy (DOE) programs in South Africa; and a listing of International aid to South Africa.

  19. Microfluidics and Nanoscale Research Profile

    E-Print Network [OSTI]

    Microfluidics and Nanoscale Science Research Profile Our research group is engaged in a broad range of activities in the general area of microfluidics and nanoscale science. At a primary level, our interest that when compared to macroscale tech- nology, microfluidic systems engender a number of distinct advantages

  20. Renewable Energy Carriers Research Profile

    E-Print Network [OSTI]

    Giger, Christine

    Renewable Energy Carriers Research Profile The research program of the Professorship of Renewable applied to renewable energy technologies. The fundamental research focus comprises high-temperature heat (radiative fluxes >10 000 kW/m2 ; temperatures >1000°C; heating rates >1000°C/s) + Renewable Energy

  1. Validation of the MCNPX-PoliMi Code to Design a Fast-Neutron Multiplicity Counter

    SciTech Connect (OSTI)

    J. L. Dolan; A. C. Kaplan; M. Flaska; S. A. Pozzi; D. L. Chichester

    2012-07-01

    Many safeguards measurement systems used at nuclear facilities, both domestically and internationally, rely on He-3 detectors and well established mathematical equations to interpret coincidence and multiplicity-type measurements for verifying quantities of special nuclear material. Due to resource shortages alternatives to these existing He-3 based systems are being sought. Work is also underway to broaden the capabilities of these types of measurement systems in order to improve current multiplicity analysis techniques. As a part of a Material Protection, Accounting, and Control Technology (MPACT) project within the U.S. Department of Energy's Fuel Cycle Technology Program we are designing a fast-neutron multiplicity counter with organic liquid scintillators to quantify important quantities such as plutonium mass. We are also examining the potential benefits of using fast-neutron detectors for multiplicity analysis of advanced fuels in comparison with He-3 detectors and testing the performance of such designs. The designs are being developed and optimized using the MCNPX-PoliMi transport code to study detector response. In the full paper, we will discuss validation measurements used to justify the use of the MCNPX-PoliMi code paired with the MPPost multiplicity routine to design a fast neutron multiplicity counter with liquid scintillators. This multiplicity counter will be designed with the end goal of safeguarding advanced nuclear fuels. With improved timing qualities associated with liquid scintillation detectors, we can design a system that is less limited by nuclear materials of high activities. Initial testing of the designed system with nuclear fuels will take place at Idaho National Laboratory in a later stage of this collaboration.

  2. T-1025 IU SciBath-768 detector tests in MI-12

    SciTech Connect (OSTI)

    Tayloe, Rex; Cooper, R.; Garrison, L.; Thornton, T.; Rebenitsch, L.; DeJongh, Fritz; Loer, Benjamin; Ramberg, Erik; Yoo, Jonghee; /Fermilab

    2012-02-11

    This is a memorandum of understanding between the Fermi National Accelerator Laboratory (Fermilab) and the experimenters of Department of Physics and Center for Exploration of Energy and Matter, Indiana University, who have committed to participate in detector tests to be carried out during the 2012 Fermilab Neutrino program. The memorandum is intended solely for the purpose of recording expectations for budget estimates and work allocations for Fermilab, the funding agencies and the participating institutions. it reflects an arrangement that currently is satisfactory to the parties; however, it is recognized and anticipated that changing circumstances of the evolving research program will necessitate revisions. The parties agree to modify this memorandum to reflect such required adjustments. Actual contractual obligations will be set forth in separate documents. The experimenters propsoe to test their prototype 'SciBat-768' detector in the MI-12 building for 3 months (February-April) in Spring 2012. The major goal of this effort is to measure or limit the flux of beam-induced neutrons in a far-off-axis (> 45{sup o}) location of the Booster Neutrino Beamline (BNB). This flux is of interest for a proposed coherent neutral-current neutrino-argon elastic scattering experiment. A second goal is to collect more test data for the SciBath-768 to enable better understanding and calibration of the device. The SciBath-768 detector successfully ran for 3 months in the MINOS Underground Area in Fall 2011 as testbeam experiment T-1014 and is currently running above ground in the MINOS service building. For the run proposed here, the experiments are requesting: space in MI-12 in which to run the SciBath detector during February-April 2012 while the BNB is operating; technical support to help with moving the equipment on site; access to power, internet, and accelerator signals; and a small office space from which to run and monitor the experiment.

  3. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    Office of Student Financial Aid The Welcome Center · 42 West Warren · P.O. Box 2340 · Detroit, MI. O. Box 2340 · 42 West Warren · Detroit, MI 48202-0340 2015-16 Verification of 2014 Income - Student · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne

  4. Spring leaf flush in aspen (Populus tremuloides) clones is altered by long-term growth at elevated carbon dioxide and elevated ozone concentration

    E-Print Network [OSTI]

    carbon dioxide and elevated ozone concentration Justin M. McGrath a , David F. Karnosky b , Elizabeth A. In this study, we investigated spring leaf flush and how long-term growth at elevated carbon dioxide growth and produc- tivity are increasing atmospheric carbon dioxide concentration ([CO2]) and increasing

  5. Microelectromechanical apparatus for elevating and tilting a platform

    DOE Patents [OSTI]

    Miller, Samuel Lee; McWhorter, Paul Jackson; Rodgers, Murray Steven; Sniegowski, Jeffry J.; Barnes, Stephen M.

    2004-07-06

    A microelectromechanical (MEM) apparatus is disclosed which has a platform that can be elevated above a substrate and tilted at an arbitrary angle using a plurality of flexible members which support the platform and control its movement. Each flexible member is further controlled by one or more MEM actuators which act to bend the flexible member. The MEM actuators can be electrostatic comb actuators or vertical zip actuators, or a combination thereof. The MEM apparatus can include a mirror coating to form a programmable mirror for redirecting or switching one or more light beams for use in a projection display. The MEM apparatus with-the mirror coating also has applications for switching light beams between optical fibers for use in a local area fiber optic network, or for use in fiber optic telecommunications or data communications systems.

  6. Microelectromechanical apparatus for elevating and tilting a platform

    DOE Patents [OSTI]

    Miller, Samuel Lee (Albuquerque, NM); McWhorter, Paul Jackson (Albuquerque, NM); Rodgers, Murray Steven (Albuquerque, NM); Sniegowski, Jeffry J. (Edgewood, NM); Barnes, Stephen M. (Albuquerque, NM)

    2003-04-08

    A microelectromechanical (MEM) apparatus is disclosed which has a platform that can be elevated above a substrate and tilted at an arbitrary angle using a plurality of flexible members which support the platform and control its movement. Each flexible member is further controlled by one or more MEM actuators which act to bend the flexible member. The MEM actuators can be electrostatic comb actuators or vertical zip actuators, or a combination thereof. The MEM apparatus can include a mirror coating to form a programmable mirror for redirecting or switching one or more light beams for use in a projection display. The MEM apparatus with the mirror coating also has applications for switching light beams between optical fibers for use in a local area fiber optic network, or for use in fiber optic telecommunications or data communications systems.

  7. Profiling

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration wouldMass mapSpeedingProgramExemptions | NationalProcurementwork up forJack

  8. State coal profiles, January 1994

    SciTech Connect (OSTI)

    Not Available

    1994-02-02

    The purpose of State Coal Profiles is to provide basic information about the deposits, production, and use of coal in each of the 27 States with coal production in 1992. Although considerable information on coal has been published on a national level, there is a lack of a uniform overview for the individual States. This report is intended to help fill that gap and also to serve as a framework for more detailed studies. While focusing on coal output, State Coal Profiles shows that the coal-producing States are major users of coal, together accounting for about three-fourths of total US coal consumption in 1992. Each coal-producing State is profiled with a description of its coal deposits and a discussion of the development of its coal industry. Estimates of coal reserves in 1992 are categorized by mining method and sulfur content. Trends, patterns, and other information concerning production, number of mines, miners, productivity, mine price of coal, disposition, and consumption of coal are detailed in statistical tables for selected years from 1980 through 1992. In addition, coal`s contribution to the State`s estimated total energy consumption is given for 1991, the latest year for which data are available. A US summary of all data is provided for comparing individual States with the Nation as a whole. Sources of information are given at the end of the tables.

  9. A method to construct refracting profiles

    E-Print Network [OSTI]

    N. Alamo; C. Criado

    2004-04-13

    We propose an original method for determining suitable refracting profiles between two media to solve two related problems: to produce a given wave front from a single point source after refraction at the refracting profile, and to focus a given wave front in a fixed point. These profiles are obtained as envelopes of specific families of Cartesian ovals. We study the singularities of these profiles and give a method to construct them from the data of the associated caustic.

  10. Project Profile: Direct Supercritical Carbon Dioxide Receiver...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Receiver Development Project Profile: Direct Supercritical Carbon Dioxide Receiver Development National Renewable Energy Laboratory logo The National Renewable Energy...

  11. Formulating and Implementing Profiling over Adaptive Ranges

    E-Print Network [OSTI]

    Sherwood, Tim

    be implemented for range-adaptive profiling. RAP can be used on various profiles, such as PCs, load values may easily be lost in a sea of data. We present range-adaptive profiling (RAP) as a new and general value locality. We propose two methods of implementation of RAP, one in software and the other

  12. The Effect of Elevated Temperature on Concrete Materials and Structures - a Literature Review.

    SciTech Connect (OSTI)

    Naus, Dan J

    2006-03-01

    The objective of this limited study was to provide an overview of the effects of elevated temperature on the behavior of concrete materials and structures. In meeting this objective the effects of elevated temperatures on the properties of ordinary Portland cement concrete constituent materials and concretes are summarized. The effects of elevated temperature on high-strength concrete materials are noted and their performance compared to normal strength concretes. A review of concrete materials for elevated-temperature service is presented. Nuclear power plant and general civil engineering design codes are described. Design considerations and analytical techniques for evaluating the response of reinforced concrete structures to elevated-temperature conditions are presented. Pertinent studies in which reinforced concrete structural elements were subjected to elevated temperatures are described.

  13. T-608: HP Virtual Server Environment Lets Remote Authenticated Users Gain Elevated Privileges

    Broader source: Energy.gov [DOE]

    A potential security vulnerability has been identified in HP Virtual Server Environment for Windows. The vulnerability could be exploited remotely to elevate privileges.

  14. Digital Elevation Model, 0.5-m, Barrow Environmental Observatory, Alaska, 2012

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Gangodagamage, Chandana; Wilson, Cathy; Rowland, Joel

    The dataset is a digital elevation model, DEM, of a 2km by 7km region in the vicinity of the Barrow Environmental Observatory near Barrow, Ak.

  15. Aerosol measurements at a high-elevation site: composition, size, and cloud condensation nuclei activity

    E-Print Network [OSTI]

    Friedman, Beth

    Measurements of cloud condensation nuclei (CCN) concentrations, single particle composition and size distributions at a high-elevation research site from March 2011 are presented.

  16. Digital Elevation Model, 0.5-m, Barrow Environmental Observatory, Alaska, 2012

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Wilson,Cathy; Rowland,Joel; Gangodagamage,Chandana

    2013-12-08

    The dataset is a digital elevation model, DEM, of a 2km by 7km region in the vicinity of the Barrow Environmental Observatory near Barrow, Ak.

  17. Conserved Regulation of p53 Network Dosage by MicroRNA–125b Occurs through Evolving miRNA–Target Gene Pairs

    E-Print Network [OSTI]

    Le, Minh T. N.

    MicroRNAs regulate networks of genes to orchestrate cellular functions. MiR-125b, the vertebrate homologue of the Caenorhabditis elegans microRNA lin-4, has been implicated in the regulation of neural and hematopoietic ...

  18. {00012119.DOC /} Graduate Medical Education 540 E. Canfield Detroit, MI 48201 Phone 313-577-5189 Fax 313-577-5245

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    {00012119.DOC /} Graduate Medical Education 540 E. Canfield · Detroit, MI 48201 · Phone 313; This agreement of appointment by and between WSU, whose address is 540 East Canfield, Detroit, Michigan 48201

  19. ANRV253-MI59-05 ARI 21 April 2005 18:7 Diversity and Evolution of

    E-Print Network [OSTI]

    Plotkin, Joshua B.

    ANRV253-MI59-05 ARI 21 April 2005 18:7 R E V I E W S IN A D V A N CE Diversity and Evolution: pohlschr@sas.upenn.edu, njhand@sas.upenn.edu, kdilks@sas.upenn.edu, alexh@sas.upenn.edu 2 University of L. Rev. Microbiol. 2005. 59:91­111 doi: 10.1146/ annurev.micro.59.030804.121353 Copyright c 2005

  20. Refracting profiles and generalized holodiagrams

    E-Print Network [OSTI]

    C. Criado; N. Alamo; H. Rabal

    2007-03-09

    The recently developed concept of refracting profiles and that of refraction holodiagrams are combined so that the classical Abramson holodiagrams can be generalized taking into account a wider class of wave fronts and refraction at an interface, whenever regions of caustics are avoided. These holodiagrams are obtained as envelopes of specific families of Cartesian Ovals with an appropriate parametrization. Classical and reflecting holodiagrams are particular cases of this class. Several of the properties of the classical holodiagrams are shared by their richer generalized versions

  1. Plains Elevated Convection at Night (PECAN) Experiment Science Plan

    SciTech Connect (OSTI)

    Turner, D; Parsons, D; Geerts, B

    2015-03-01

    The Plains Elevated Convection at Night (PECAN) experiment is a large field campaign that is being supported by the National Science Foundation (NSF) with contributions from the National Oceanic and Atmospheric Administration (NOAA), the National Atmospheric and Space Administration (NASA), and the U.S. Department of Energy (DOE). The overarching goal of the PECAN experiment is to improve the understanding and simulation of the processes that initiate and maintain convection and convective precipitation at night over the central portion of the Great Plains region of the United States (Parsons et al. 2013). These goals are important because (1) a large fraction of the yearly precipitation in the Great Plains comes from nocturnal convection, (2) nocturnal convection in the Great Plains is most often decoupled from the ground and, thus, is forced by other phenomena aloft (e.g., propagating bores, frontal boundaries, low-level jets [LLJ], etc.), (3) there is a relative lack of understanding how these disturbances initiate and maintain nocturnal convection, and (4) this lack of understanding greatly hampers the ability of numerical weather and climate models to simulate nocturnal convection well. This leads to significant uncertainties in predicting the onset, location, frequency, and intensity of convective cloud systems and associated weather hazards over the Great Plains.

  2. Myc induced miR-144/451 contributes to the acquired imatinib resistance in chronic myelogenous leukemia cell K562

    SciTech Connect (OSTI)

    Liu, Li, E-mail: liuli029@yahoo.cn [Department of Hematology, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038 (China)] [Department of Hematology, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038 (China); Wang, Sitao; Chen, Renan; Wu, Yanlan; Zhang, Bei; Huang, Siyong; Zhang, Jingyi; Xiao, Fang; Wang, Meng; Liang, Yingmin [Department of Hematology, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038 (China)] [Department of Hematology, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038 (China)

    2012-08-24

    Highlights: Black-Right-Pointing-Pointer Increased c-myc expression in imatinib resistant CML cells. Black-Right-Pointing-Pointer c-myc contributes the imatinib resistance in CML cells. Black-Right-Pointing-Pointer c-myc transcriptionally reduces the expression of miR-144/451 in K562R cells. Black-Right-Pointing-Pointer Restoration of miR-144/451 reverses the resistance of K562R cells to imatinib. -- Abstract: Imatinib resistance remains the big hurdle for CML therapy. Previous study reveals that c-myc is important for bcr-abl CML cell proliferation, while its role in imatinib resistance is largely unknown. In this study, we first found that c-myc expression is upregulated in imatinib resistant K562R cells, which in turn enhances the expression of miR-144/451. Knockdown of c-myc or restoration of miR-144/451 in the K562R cells sensitizes K562R cells to imatinib therapy. Our study here reveals an regulatory pathway between myc and miR-144/451 and highlights that targeting either myc or miR-144/451 might be valuable for eliminating the imatinib resistant CML cells.

  3. Functional profiling of microRNAs in stallions 

    E-Print Network [OSTI]

    Wang, Aaron Stephen

    2013-02-04

    Bioinformatics analysis of miRNA sequences and primer design ........................14 Total RNA extraction from tissues and sperm ......................................................15 Total RNA polyadenylation..., the mature miRNA strands are extended through the use of poly-A polymerase (Fig. 2.2), reverse transcribed into srcDNA with a reverse transcription (RT) primer and reverse transcriptase (RTase; Fig. 2.3), and then analyzed for expression levels through...

  4. ORIGINAL PAPER Effects of elevated CO2 and soil water content on phytohormone

    E-Print Network [OSTI]

    DeLucia, Evan H.

    ORIGINAL PAPER Effects of elevated CO2 and soil water content on phytohormone transcript induction the abundance of SA compared with plants grown in ambient CO2. A mild reduction in soil water content had herbivory. When applied in combination, elevated CO2 and reduced soil water content suppressed

  5. Contracting Rail Freight Services for Country Elevators in the Texas Panhandle. 

    E-Print Network [OSTI]

    Fuller, Stephen

    1984-01-01

    that of the 10 elevators to be up graded. The plant size cost model, which was most lik~ ~he bushel storage capacity of the upgraded facIhty, was selected for estimating elevator costs. Plant depreciation estimates of existing plants varied and in some cases... ............................................................................ 4 Wheat Supply and Farm Storage Capacity ..................................... 4 Farm Assembly Cost. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. 4 Farm Storage Cost...

  6. EVIDENCE OF ELEVATED OZONE CONCENTRATIONS ON FORESTED SLOPES OF THE LOWER FRASER VALLEY, BRITISH

    E-Print Network [OSTI]

    McKendry, Ian

    EVIDENCE OF ELEVATED OZONE CONCENTRATIONS ON FORESTED SLOPES OF THE LOWER FRASER VALLEY, BRITISH, hourly average ozone concentrations were mea- sured at three sites of differing elevation (188, 588. Sites experienced ozone concentrations ranging from 0 to 88 ppb in 2001, and 0 to 96 ppb in 2002. Daily

  7. Evolution of resistance to white pine blister rust in high-elevation pines

    E-Print Network [OSTI]

    Tavener, Simon

    Evolution of resistance to white pine blister rust in high-elevation pines Mike Antolin, Stuart Station, USDA Forest Service Thanks: NSF award 0734267, USDA Forest Service Evolution of resistance ­ p. 1/74 #12;The basic ecology Evolution of resistance ­ p. 2/74 #12;High-elevation White Pines · Habitat: dry

  8. A Database of Herbaceous Vegetation Responses to Elevated Atmospheric CO2

    E-Print Network [OSTI]

    A Database of Herbaceous Vegetation Responses to Elevated Atmospheric CO2 ORNL/CDIAC-124 NDP-073/CDIAC-124 NDP-073 A DATABASE OF HERBACEOUS VEGETATION RESPONSES TO ELEVATED ATMOSPHERIC CO2 Contributed by Michael H. Jones Peter S. Curtis Department of Evolution, Ecology, and Organismal Biology The Ohio State

  9. UBC Social Ecological Economic Development Studies (SEEDS) Student Report Elevator Drive Systems Energy Consumption Study Report

    E-Print Network [OSTI]

    Energy Consumption Study Report Benny ChunYin Chan University of British Columbia EECE 492 April 6th the current status of the subject matter of a project/report". #12;Elevator Drive Systems Energy Consumption Study Report April 2012 0 2012 Elevator Drive Systems Energy Consumption Study Report Benny CY Chan UBC

  10. PREDICTING THE PERFORMANCE OF AN ELEVATED WATER TABLE FOR PREVENTING ACID

    E-Print Network [OSTI]

    Aubertin, Michel

    PREDICTING THE PERFORMANCE OF AN ELEVATED WATER TABLE FOR PREVENTING ACID MINE DRAINAGE M. The effectiveness of an elevated water table in preventing acid mine drainage (AMD) can be quantified using diffusion de l'oxygène en milieu quasi saturé. Cette efficacité à empêcher le drainage minier acide (DMA

  11. Physiological impacts of elevated carbon dioxide and ocean acidification Rachael M. Heuer* and Martin Grosell*

    E-Print Network [OSTI]

    Grosell, Martin

    Physiological impacts of elevated carbon dioxide and ocean acidification on fish Rachael M. Heuer, Grosell M. Physiological impacts of elevated carbon dioxide and ocean acidification on fish. Am J Physiol in dynamic regulation of acid-base transport pathways across species, exposure levels, and exposure duration

  12. Biomass and toxicity responses of poison ivy (Toxicodendron radicans) to elevated

    E-Print Network [OSTI]

    Mohan, Jacqueline E.

    Biomass and toxicity responses of poison ivy (Toxicodendron radicans) to elevated atmospheric CO2 dioxide (CO2), but pre- vious work done in controlled growth chambers shows that other vines exhibit large growth enhancement from elevated CO2. Rising CO2 is potentially responsible for the increased vine

  13. The role of plant species in biomass production and response to elevated CO2 and N

    E-Print Network [OSTI]

    Thomas, David D.

    REPORT The role of plant species in biomass production and response to elevated CO2 and N Joseph M that factorially manipulated plant diversity, CO2, and N, we quantified the effects of the presence of species having less variation in biomass over time. The response of plant biomass to elevated N, but not CO2

  14. Elevated CO2 stimulates grassland soil respiration by increasing carbon inputs rather than by enhancing soil

    E-Print Network [OSTI]

    Minnesota, University of

    Elevated CO2 stimulates grassland soil respiration by increasing carbon inputs rather than It is not clear whether the consistent positive effect of elevated CO2 on soil respiration (soil carbon flux, SCF) results from increased plant and microbial activity due to (i) greater C availability through CO2-induced

  15. Impacts of Elevated Atmospheric CO2and O3on Paper Birch (Betula papyrifera): Reproductive Fitness

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Darbah, Joseph N. T.; Kubiske, Mark E.; Nelson, Neil; Oksanen, Elina; Vaapavuori, Elina; Karnosky, David F.

    2007-01-01

    Atmospheric CO2and tropospheric O3are rising in many regions of the world. Little is known about how these two commonly co-occurring gases will affect reproductive fitness of important forest tree species. Here, we report on the long-term effects of CO3and O3for paper birch seedlings exposed for nearly their entire life history at the Aspen FACE (Free Air Carbon Dioxide Enrichment) site in Rhinelander, WI. Elevated CO2increased both male and female flower production, while elevated O3increased female flower production compared to trees in control rings. Interestingly, very little flowering has yet occurred in combined treatment. Elevated CO2had significant positive effect on birchmore »catkin size, weight, and germination success rate (elevated CO2increased germination rate of birch by 110% compared to ambient CO2concentrations, decreased seedling mortality by 73%, increased seed weight by 17%, increased root length by 59%, and root-to-shoot ratio was significantly decreased, all at 3 weeks after germination), while the opposite was true of elevated O3(elevated O3decreased the germination rate of birch by 62%, decreased seed weight by 25%, and increased root length by 15%). Under elevated CO2, plant dry mass increased by 9 and 78% at the end of 3 and 14 weeks, respectively. Also, the root and shoot lengths, as well as the biomass of the seedlings, were increased for seeds produced under elevated CO2, while the reverse was true for seedlings from seeds produced under the elevated O3. Similar trends in treatment differences were observed in seed characteristics, germination, and seedling development for seeds collected in both 2004 and 2005. Our results suggest that elevated CO2and O3can dramatically affect flowering, seed production, and seed quality of paper birch, affecting reproductive fitness of this species.« less

  16. Modeling pulse profiles of accreting millisecond pulsars

    E-Print Network [OSTI]

    Juri Poutanen

    2008-09-14

    I review the basic observational properties of accreting millisecond pulsars that are important for understanding the physics involved in formation of their pulse profiles. I then discuss main effects responsible for shaping these profiles. Some analytical results that help to understand the results of simulations are presented. Constraints on the pulsar geometry and the neutron star equation of state obtained from the analysis of the pulse profiles are discussed.

  17. US nuclear warhead facility profiles

    SciTech Connect (OSTI)

    Cochran, T.B.; Arkin, W.A.; Norris, R.S.; Hoenig, M.M.

    1987-01-01

    US Nuclear Warhead Facility Profiles is the third volume of the Nuclear Weapons Databook, a series published by the Natural Resources Defense Council. This volume reviews the different facilities in the US nuclear warhead complex. Because of the linkage between nuclear energy and nuclear weapons, the authors cover not only those facilities associated mainly with nuclear power research, but also those well known for weapons development. They are: the Argonne National Laboratory; the Hanford Reservation; the Oak Ridge National Laboratory; the Pantex plant; the Los Alamos Test Site; the Rocky Flats plant; the Sandia National Laboratories; and a host of others. Information on each facility is organized into a standard format that makes the book easy to use. The reader will find precise information ranging from a facility's address to its mission, management, establishment, budget, and staff. An additional, more in-depth presentation covers the activities and technical process of each facility. Maps, pictures, and figures complement the text.

  18. Santa Cruz Harbor Commercial Fishing Community Profile

    E-Print Network [OSTI]

    Pomeroy, Caroline

    2008-01-01

    Statistics Branch. Commercial fishing licenses and permitsSanta Cruz Harbor Commercial Fishing Community Profile, Julythe rate or level of fishing mortality that jeopardizes the

  19. Manufacturing of Profiles for Lightweight Structures

    SciTech Connect (OSTI)

    Chatti, Sami; Kleiner, Matthias

    2007-04-07

    The paper shows some investigation results about the production of straight and curved lightweight profiles for lightweight structures and presents their benefits as well as their manufacturing potential for present and future lightweight construction. A strong emphasis is placed on the manufacturing of straight and bent profiles by means of sheet metal bending of innovative products, such as tailor rolled blanks and tailored tubes, and the manufacturing of straight and curved profiles by the innovative procedures curved profile extrusion and composite extrusion, developed at the Institute of Forming Technology and Lightweight Construction (IUL) of the University of Dortmund.

  20. PROJECT PROFILE: Vermont Energy Investment Corporation (Solar...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Vermont Energy Investment Corporation (Solar Market Pathways) PROJECT PROFILE: Vermont Energy Investment Corporation (Solar Market Pathways) Title: Vermont Solar Development Plan...

  1. Soil Profile Rebuilding Specification (Brief Version)--1 Soil Profile Rebuilding--Abbreviated Specification

    E-Print Network [OSTI]

    Virginia Tech

    Soil Profile Rebuilding Specification (Brief Version)--1 Soil Profile Rebuilding--Abbreviated Specification Specification for Restoration of Graded and Compacted Soils that will be Vegetated 1. PURPOSE AND DESCRIPTION Purpose Soil Profile Rebuilding is an appropriate soil restoration technique for sites where

  2. SVMs with Profile-Based Kernels 1 Support Vector Machines with Profile-Based Kernels for

    E-Print Network [OSTI]

    Pace, Gordon J.

    amount of new protein sequences. The resulting sequences describe a protein in terms of the amino acids, the frequency that each amino acid appears in that column. Once a profile is available, a new sequence canSVMs with Profile-Based Kernels 1 Support Vector Machines with Profile-Based Kernels for Remote

  3. PERFORMANCE EFFECTS OF AIR VELOCITY PROFILES IN

    E-Print Network [OSTI]

    PERFORMANCE EFFECTS OF AIR VELOCITY PROFILES IN A RESIDENTIAL HEAT PUMP By NATHAN ANDREW WEBER PROFILES IN A RESIDENTIAL HEAT PUMP Thesis Approved: _______________________________________ Thesis Advisor the air speed transducer mount and the Plexiglas model of the heat pump. Ipseng Iu and myself worked side

  4. STUDY ABROAD IN LINGUISTICS STUDENT ACADEMIC PROFILES

    E-Print Network [OSTI]

    STUDY ABROAD IN LINGUISTICS STUDENT ACADEMIC PROFILES LINGUISTICS--LANGUAGE STUDIES MAJOR--12 COURSES Language Studies majors take 6 Linguistics classes (5 required, one elective), 2 Literature courses in the language of concentration and 4 Area Studies classes Profile of a Language Studies

  5. Mitsubishi iMiEV: An Electric Mini-Car in NREL's Advanced Technology Vehicle Fleet (Fact Sheet)

    SciTech Connect (OSTI)

    Not Available

    2011-10-01

    This fact sheet highlights the Mitsubishi iMiEV, an electric mini-car in the advanced technology vehicle fleet at the National Renewable Energy Laboratory (NREL). In support of the U.S. Department of Energy's fast-charging research efforts, NREL engineers are conducting charge and discharge performance testing on the vehicle. NREL's advanced technology vehicle fleet features promising technologies to increase efficiency and reduce emissions without sacrificing safety or comfort. The fleet serves as a technology showcase, helping visitors learn about innovative vehicles that are available today or are in development. Vehicles in the fleet are representative of current, advanced, prototype, and emerging technologies.

  6. Feature Shape and Elevation Based Road Classification and Extraction on High Spatial

    E-Print Network [OSTI]

    Carbonara, Joaquin

    Feature Shape and Elevation Based Road Classification and Extraction on High Spatial Resolution #12; 2 Abstract: Classification and extraction of geospatial features from high spatial resolution. However, the conventional method of human interpretation and digitizing cannot fulfill the requirements

  7. A User Guide for Marsh Analysis and Planning Tool Incorporating Tides and Elevations

    E-Print Network [OSTI]

    ................... 18 3) Vertical Datum (VDatum) Transformation ....................... 20 c. Digital Elemation Models on a combination of a digital elevation model (DEM) derived from GPS observations, local tidal datums, and grass

  8. Electronic structure of perovskite oxide surfaces at elevated temperatures and its correlation with oxygen reduction reactivity

    E-Print Network [OSTI]

    Chen, Yan, Ph. D. Massachusetts Institute of Technology

    2014-01-01

    The objective is to understand the origin of the local oxygen reduction reaction (ORR) activity on the basis of the local electronic structure at the surface of transition metal oxides at elevated temperatures and in oxygen ...

  9. U-112: PostgreSQL Bugs Let Remote Authenticated Users Gain Elevated...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    2: PostgreSQL Bugs Let Remote Authenticated Users Gain Elevated Privileges, Inject SQL Commands, and Spoof Certificates U-112: PostgreSQL Bugs Let Remote Authenticated Users Gain...

  10. Systemic Elevation of PTEN Induces a Tumor-Suppressive Metabolic State

    E-Print Network [OSTI]

    Garcia-Cao, Isabel

    Decremental loss of PTEN results in cancer susceptibility and tumor progression. PTEN elevation might therefore be an attractive option for cancer prevention and therapy. We have generated several transgenic mouse lines ...

  11. Carbon Dynamics in Aquatic Ecosystems in Response to Elevated Atmospheric CO2 and Altered Nutrients Availability

    E-Print Network [OSTI]

    Song, Chao

    2011-04-26

    Aquatic ecosystems will experience altered inorganic carbon, nitrogen and phosphorous availability in the future due to elevated atmospheric CO2, stronger stratification and anthropogenic activities. Despite its importance in modulating global...

  12. Fine root dynamics along an elevational gradient in tropical Amazonian and Andean forests

    E-Print Network [OSTI]

    Malhi, Yadvinder

    synchronised to seasonality of solar radiation. Finally, we provide the first insights into root growth-level productivity is limited. To date, studies from only three elevational transects have provided data on fine root

  13. Effects of Vegetation Structure and Elevation on Lower Keys Marsh Rabbit Density 

    E-Print Network [OSTI]

    Dedrickson, Angela

    2012-02-14

    LKMR density on lands managed by the United States Navy, Naval Air Station Key West and evaluate how vegetation structure and patch elevation effect LKMR population density. I conducted fecal pellet counts to determine LKMR density, collected...

  14. MMPI-A: test of behavioral correlates associated with elevated scales in a sample of female juvenile delinquents 

    E-Print Network [OSTI]

    Stefanov, Michael Lee

    2006-10-30

    probability of aggressive behavior. Behavioral correlates associated with elevated MMPI-A scale 9 are impulsive behaviors, grandiose self- perception, and insensitivity. Elevations on scales 4 and 9 are not the only elevated MMPI scales commonly.... Nonconformity, unconventional, and socially deviant Scale 9 1. Impulsivity and restlessness 2. Greater likelihood and delinquent behaviors Content Scales Adolescent-Anger 1. Irritability and physical aggressiveness Adolescent...

  15. Effects of plant diversity, N fertilization, and elevated carbon dioxide on grassland soil N cycling in a

    E-Print Network [OSTI]

    Thomas, David D.

    Effects of plant diversity, N fertilization, and elevated carbon dioxide on grassland soil N evaluated how elevated atmospheric carbon dioxide (CO2), N fertilization, and plant species richness alter can limit the response of plant productivity to both elevated atmo- spheric carbon dioxide (CO2

  16. Abstract The results of published and unpublished ex-periments investigating the impacts of elevated [CO2] on

    E-Print Network [OSTI]

    of elevated [CO2] on the chemistry of leaf litter and decomposition of plant tissues are summarized. The data plants under elevated [CO2] have an impact on decomposition processes. A meta-analysis of data from was 7.1% lower in elevated [CO2] compared to that in ambient [CO2]. This statistically significant

  17. Rhizodeposition-induced decomposition increases N availability to wild and cultivated wheat genotypes under elevated CO2

    E-Print Network [OSTI]

    van Kessel, Chris

    genotypes under elevated CO2 Marie-Anne de Graaff a,b,*, Chris Van Kessel a , Johan Six a a Department Available online 11 March 2009 Keywords: Elevated CO2 Rhizodeposition N mineralization 13 C 15 N Genotypes a b s t r a c t Elevated CO2 may increase nutrient availability in the rhizosphere bystimulating N

  18. Interannual climatic variation mediates elevated CO2 and O3 effects on forest growth

    E-Print Network [OSTI]

    ). For example, some include elevated [CO2] effects on photosynthesis to estimate the fraction of anthropo- genicInterannual climatic variation mediates elevated CO2 and O3 effects on forest growth M A R K E . K carbon dioxide ([CO2]; 518 lL LÀ1 ) and ozone concentrations ([O3]; 1.5 Â background of 30­40 nL LÀ1

  19. Elevated CO2 stimulates grassland soil respiration by increasing carbon inputs rather than by enhancing soil

    E-Print Network [OSTI]

    Thomas, David D.

    Elevated CO2 stimulates grassland soil respiration by increasing carbon inputs rather than by enhancing soil moisture E . C A R O L A D A I R * § , P E T E R B . R E I C H , J A R E D J . T R O It is not clear whether the consistent positive effect of elevated CO2 on soil respiration (soil carbon flux, SCF

  20. State electricity profiles, March 1999

    SciTech Connect (OSTI)

    1999-03-01

    Due to the role electricity plays in the Nation`s economic and social well-being, interested parties have been following the electric power industry`s transition by keeping abreast of the restructuring and deregulation events that are taking place almost daily. Much of the attention centers around the States and how they are restructuring the business of electricity supply within their respective jurisdictions. This report is designed to profile each State and the District of Columbia regarding not only their current restructuring activities, but also their electricity generation and concomitant statistics from 1986 through 1996. Included are data on a number of subject areas including generating capability, generation, revenues, fuel use, capacity factor for nuclear plants, retail sales, and pollutant emissions. Although the Energy Information Administration (EIA) publishes this type of information, there is a lack of a uniform overview for each individual State. This report is intended to help fill that gap and also to serve as a framework for more detailed studies. In addition to basic statistics in tables and graphs, a textual section is provided for each State, discussing some of the points relative to electricity production that are noteworthy in, or unique to, that particular State. Also, each State is ranked according to the place it holds, as compared to the rest of the states, in various relevant areas, such as its average price of electricity per kilowatthour, its population, and its emissions of certain atmospheric pollutants. The final chapter covers the Nation as a whole. 451 figs., 520 tabs.

  1. Continuous profiling of magnetotelluric fields

    SciTech Connect (OSTI)

    Verdin, C.T.

    1991-05-01

    The magnetotelluric (MT) method of mapping ground electrical conductivity is traditionally based on measurement of the surface impedance at widely spaced stations to infer models of the subsurface through a suitable pseudo 1-D inverse or with linearized least-squares inversion for 2- or 3-D geoelectric media. It is well known that small near-surface inhomogeneities can produce spatial discontinuities in the measured electric fields over a wide frequency range and may consequently bias the impedance on a very local scale. Inadequate station spacing effectively aliases the electric field measurements and results in distortions that cannot be removed in subsequent processing or modelling. In order to fully exploit the benefits of magnetotellurics in complex geological environments, closely spaced measurements must be used routinely. This thesis entertains an analysis of MT data taken along continuous profiles and is a first step that will allow more encompassing 2-D sampling techniques to become viable in the years to come. The developments presented here are to a large extent motivated by the physical insight gained from low-contrast solutions to the forward MT problem. These solutions describe the relationship between a perturbation in the electrical conductivity of the subsurface and the ensuing perturbation of the MT response as the output of a linear system. Albeit strictly accurate in a limited subset of practical exploration problems, the linearized solutions allow one to pursue a model independent study of the response characteristics of MT data. In fact, these solutions yield simple expressions for 1-,2-, and 3-D resistivity models which are here examined in progressive sequence.

  2. Miniature lightweight x-ray optics (MiXO) for surface elemental composition mapping of asteroids and comets

    E-Print Network [OSTI]

    Hong, Jaesub

    2016-01-01

    The compositions of diverse planetary bodies are of fundamental interest to planetary science, providing clues to the formation and evolutionary history of the target bodies and the Solar system as a whole. Utilizing the X-ray fluorescence unique to each atomic element, X-ray imaging spectroscopy is a powerful diagnostic tool of the chemical and mineralogical compositions of diverse planetary bodies. Until now the mass and volume of focusing X-ray optics have been too large for resource-limited in-situ missions, so near-target X-ray observations of planetary bodies have been limited to simple collimator-type X-ray instruments. We introduce a new Miniature lightweight Wolter-I focusing X-ray Optics (MiXO) using metal-ceramic hybrid X-ray mirrors based on electroformed nickel replication and plasma thermal spray processes. MiXO can enable compact, powerful imaging X-ray telescopes suitable for future planetary missions. We illustrate the need for focusing X-ray optics in observing relatively small planetary bod...

  3. ITP Metal Casting: Energy and Environmental Profile of the U...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    and Environmental Profile of the U.S. Metal casting Industry ITP Metal Casting: Energy and Environmental Profile of the U.S. Metal casting Industry profile.pdf More Documents &...

  4. PHOTOSYNTHESIS AND RESOURCE ALLOCATION OF THREE MOJAVE DESERT GRASSES IN RESPONSE TO ELEVATED ATMOSPHERIC CO2

    SciTech Connect (OSTI)

    L. A. DEFALCO; C. K. IVANS; P. VIVIN; J. R. SEEMANN; R. S. NOWAK

    2004-01-01

    Gas exchange, biomass and N allocation were compared among three Mojave Desert grasses representing different functional types to determine if photosynthetic responses and the associated allocation of resources within the plant changed after prolonged exposure to elevated CO{sub 2}. Leaf gas exchange characteristics were measured for Bromus madritensis ssp. rubens (C{sub 3} invasive annual), Achnatherum hymenoides (C{sub 3} native perennial) and Pleuraphis rigida (C{sub 4} native perennial) exposed to 360 {micro}mol mol{sup -1} (ambient) and 1000 {micro}mol mol{sup -1} (elevated) CO{sub 2} concentrations in a glasshouse experiment, and tissue biomass and total N pools were quantified from three harvests during development. The maximum rate of carboxylation by the N-rich enzyme Rubisco (Vc{sub max}), which was inferred from the relationship between net CO{sub 2} assimilation (A{sub net}) and intracellular CO{sub 2} concentration (c{sub i}), declined in the C{sub 3} species Bromus and Achnatherum across all sampling dates, but did not change at elevated CO{sub 2} for the C{sub 4} Pleuraphis. Whole plant N remained the same between CO{sub 2} treatments for all species, but patterns of allocation differed for the short- and long-lived C{sub 3} species. For Bromus, leaf N used for photosynthesis was reallocated to reproduction at elevated CO{sub 2} as inferred from the combination of lower Vc{sub max} and N per leaf area (NLA) at elevated CO{sub 2}, but similar specific leaf area (SLA, cm{sup 2} g{sup -1}), and of greater reproductive effort (RE) for the elevated CO{sub 2} treatment. Vc{sub max}, leaf N concentration and NLA declined for the perennial Achnatherum at elevated CO{sub 2} potentially due to accumulation of carbohydrates or changes in leaf morphology inferred from lower SLA and greater total biomass at elevated CO{sub 2}. In contrast, Vc{sub max} for the C{sub 4} perennial Pleuraphis did not change at elevated CO{sub 2}, and tissue biomass and total N were the same between CO{sub 2} treatments. Adjustments in photosynthetic capacity at elevated CO{sub 2} may optimize N allocation of C{sub 3} species in the Mojave Desert, which may influence plant performance and plant-plant interactions of these co-occurring species.

  5. Comprehensive molecular profiling of lung adenocarcinoma

    E-Print Network [OSTI]

    Lander, Eric S.

    Adenocarcinoma of the lung is the leading cause of cancer death worldwide. Here we report molecular profiling of 230 resected lung adenocarcinomas using messenger RNA, microRNA and DNA sequencing integrated with copy number, ...

  6. Natural gas annual 1992: Supplement: Company profiles

    SciTech Connect (OSTI)

    Not Available

    1994-01-01

    The data for the Natural Gas Annual 1991 Supplement : Company Profiles are taken from Form EIA-176, (open quotes) Annual Report of Natural and Supplemental Gas Supply and Disposition (close quotes). Other sources include industry literature and corporate annual reports to shareholders. The companies appearing in this report are major interstate natural gas pipeline companies, large distribution companies, or combination companies with both pipeline and distribution operations. The report contains profiles of 45 corporate families. The profiles describe briefly each company, where it operates, and any important issues that the company faces. The purpose of this report is to show the movement of natural gas through the various States served by the 45 large companies profiled.

  7. Subsurface imaging with reverse vertical seismic profiles

    E-Print Network [OSTI]

    Krasovec, Mary L. (Mary Lee), 1972-

    2001-01-01

    This thesis presents imaging results from a 3D reverse vertical seismic profile (RVSP) dataset measured at a hydrocarbon bearing pinnacle reef in northern Michigan. The study presented many challenges in seismic data ...

  8. Graduate Profile Chemistry & PhysiCs

    E-Print Network [OSTI]

    Graduate Profile Chemistry & PhysiCs "...I am helping to develop low-cost solar technology." Ricky to develop low-cost solar technology. The aim of my project is to achieve increased light absorption in thin

  9. Lunar Seismic Profiling Experiment Dynamic Analysis

    E-Print Network [OSTI]

    Rathbun, Julie A.

    II I! Lunar Seismic Profiling Experiment Dynamic Analysis CONTENTS Section 1. 0 Assumptions Section. The solid curve is a plot of the specification data for the Design and Qualification of the explosive

  10. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne Center · P. O. Box 2340 · 42 West Warren · Detroit, MI 48202-0340 3/2015 Student's First Name 9-digit WSU

  11. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne · The Welcome Center · P. O. Box 2340 · 42 West Warren · Detroit, MI 48202-0340 3/2015 Student's First Name 9

  12. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    Office of Student Financial Aid The Welcome Center · 42 West Warren · P.O. Box 2340 · Detroit, MI.O. Box 2340 · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · www

  13. Maine Geological Survey Borehole Temperature Profiles

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Marvinney, Robert

    This dataset includes temperature profiles from 30 boreholes throughout Maine that were selected for their depth, location, and lithologies encountered. Depths range from about 300 feet to 2,200 feet. Most of the boreholes selected for measurement were completed in granite because this lithology can be assumed to be nearly homogeneous over the depth of the borehole. Boreholes were also selected to address gaps in existing geothermal datasets. Temperature profiles were collected in October and November, 2012.

  14. Maine Geological Survey Borehole Temperature Profiles

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Marvinney, Robert

    2013-11-06

    This dataset includes temperature profiles from 30 boreholes throughout Maine that were selected for their depth, location, and lithologies encountered. Depths range from about 300 feet to 2,200 feet. Most of the boreholes selected for measurement were completed in granite because this lithology can be assumed to be nearly homogeneous over the depth of the borehole. Boreholes were also selected to address gaps in existing geothermal datasets. Temperature profiles were collected in October and November, 2012.

  15. SU-E-J-121: Measuring Prompt Gamma Emission Profiles with a Multi...

    Office of Scientific and Technical Information (OSTI)

    MD (United States) University of Michigan, Ann Arbor, MI (United States) MD Anderson Cancer Center, Houston, TX (United States) Procure Proton Therapy Center, Oklahoma City, OK...

  16. SU-E-J-121: Measuring Prompt Gamma Emission Profiles with a Multi...

    Office of Scientific and Technical Information (OSTI)

    of Michigan, Ann Arbor, MI (United States); Mackin, D; Beddar, S MD Anderson Cancer Center, Houston, TX (United States); Zheng, Y Procure Proton Therapy Center,...

  17. Longitudinal bunch profile and electron beam energy spread

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Ring Parameters Previous: Storage Ring Operation Modes Longitudinal bunch profile and electron beam energy spread Longitudinal bunch profile depends mainly on the single bunch...

  18. Sector Profiles of Significant Large CHP Markets, March 2004...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Sector Profiles of Significant Large CHP Markets, March 2004 Sector Profiles of Significant Large CHP Markets, March 2004 In this 2004 report, three sectors were identified as...

  19. Building America Top Innovations Hall of Fame Profile - Building...

    Energy Savers [EERE]

    Top Innovations Hall of Fame Profile - Building Energy Optimization Analysis Method (BEopt) Building America Top Innovations Hall of Fame Profile - Building Energy Optimization...

  20. Michigan State University | College of Engineering | Engineering Undergraduate Studies 1410 Engineering Building, East Lansing, MI 48824-1226 | (517) 355-6616 ext. 1

    E-Print Network [OSTI]

    (30) CEM 141 General Chemistry 4 EGR 100 Introduction to Engineering Design 2 EGR 102 IntroductionMichigan State University | College of Engineering | Engineering Undergraduate Studies 1410 Engineering Building, East Lansing, MI 48824-1226 | (517) 355-6616 ext. 1 http

  1. 50,000-Watt AM Stations IA | MB | MI | MN | NE | ND | ON | SD | WI | Station News | Owners | TV Captures | Links

    E-Print Network [OSTI]

    Allen, Gale

    that broadcast with a power of 50,000 Watts day and night. Some of these stations are what was once known50,000-Watt AM Stations IA | MB | MI | MN | NE | ND | ON | SD | WI | Station News | Owners | TV Captures | Links 50,000-Watt AM stations This list includes AM stations in the United States and Canada

  2. Michigan State University | College of Engineering | Engineering Undergraduate Studies Engineering Building, 428 S. Shaw Lane, Room 1415, East Lansing MI 48824 | (517) 355-6616 ext. 1

    E-Print Network [OSTI]

    Feeny, Brian

    Building, 428 S. Shaw Lane, Room 1415, East Lansing MI 48824 | (517) 355-6616 ext. 1 http 132 Calculus I 3 MTH 133 Calculus II 4 MTH 234 Multivariable Calculus 4 MTH 235 Differential Equations Energy Systems 3 ME 422 Introduction to Combustion 3 ME 423 Intermed Mech of Deformable Solids 3 ME 425

  3. Michigan State University | College of Engineering | Engineering Undergraduate Studies Engineering Building, 428 S. Shaw Lane, Room 1415, East Lansing MI 48824 | (517) 355-6616 ext. 1

    E-Print Network [OSTI]

    Building, 428 S. Shaw Lane, Room 1415, East Lansing MI 48824 | (517) 355-6616 ext. 1 http 234 Multivariable Calculus 4 MTH 235 Differential Equations 3 PHY 183 Physics for Scientists 450 International Environmental Law & Policy 3 ME 417 Design of Alternative Energy Systems 3 ME 422

  4. Michigan State University | College of Engineering | Engineering Undergraduate Studies Engineering Building, 428 S. Shaw Lane, Room 1415, East Lansing MI 48824 | (517) 355-6616 ext. 1

    E-Print Network [OSTI]

    Building, 428 S. Shaw Lane, Room 1415, East Lansing MI 48824 | (517) 355-6616 ext. 1 http to Engineering Modeling 2 MTH 132 Calculus I 3 MTH 133 Calculus II 4 MTH 234 Multivariable Calculus 4 MTH 235 4 CEM 161 Chemistry Laboratory I 1 CHE 201 Materials and Energy Balances 3 ENE 280 Principles

  5. Evaluation of Multiplexed 16S rRNA Microbial Population Surveys Using Illumina MiSeq Platform (Seventh Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting 2012)

    ScienceCinema (OSTI)

    Tremblay, Julien [DOE JGI

    2013-01-25

    Julien Tremblay from DOE JGI presents "Evaluation of Multiplexed 16S rRNA Microbial Population Surveys Using Illumina MiSeq Platorm" at the 7th Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting held in June, 2012 in Santa Fe, NM.

  6. Society of Automotive Engineers (SAE) Technical Paper 2006-01-1041 Paper presented at SAE 2006 World Congress & Exposition, April 5, 2006, Detroit, MI

    E-Print Network [OSTI]

    Gruner, Sol M.

    Society of Automotive Engineers (SAE) Technical Paper 2006-01-1041 Paper presented at SAE 2006 and Fundamental Advances in Thermal Fluid Sciences 2006. Vol. SP-2015. (Society of Automotive Engineers, Troy, MI and reducing emissions play an essential role in the design of the new-generation automotive internal

  7. Evaluation of Multiplexed 16S rRNA Microbial Population Surveys Using Illumina MiSeq Platform (Seventh Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting 2012)

    SciTech Connect (OSTI)

    Tremblay, Julien [DOE JGI] [DOE JGI

    2012-06-01

    Julien Tremblay from DOE JGI presents "Evaluation of Multiplexed 16S rRNA Microbial Population Surveys Using Illumina MiSeq Platorm" at the 7th Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting held in June, 2012 in Santa Fe, NM.

  8. The ArgoNeuT Detector in the NuMI Low-Energy beam line at Fermilab

    E-Print Network [OSTI]

    C. Anderson; M. Antonello; B. Baller; T. Bolton; C. Bromberg; F. Cavanna; E. Church; D. Edmunds; A. Ereditato; S. Farooq; B. Fleming; H. Greenlee; R. Guenette; S. Haug; G. Horton-Smith; C. James; E. Klein; K. Lang; A. Lathrop; P. Laurens; S. Linden; D. McKee; R. Mehdiyev; B. Page; O. Palamara; K. Partyka; S. Pordes; G. Rameika; B. Rebel; B. Rossi; R. Sanders; M. Soderberg; J. Spitz; A. M. Szelc; M. Weber; T. Yang; T. Wongjirad; G. Zeller

    2012-06-05

    The ArgoNeuT liquid argon time projection chamber has collected thousands of neutrino and antineutrino events during an extended run period in the NuMI beam-line at Fermilab. This paper focuses on the main aspects of the detector layout and related technical features, including the cryogenic equipment, time projection chamber, read-out electronics, and off-line data treatment. The detector commissioning phase, physics run, and first neutrino event displays are also reported. The characterization of the main working parameters of the detector during data-taking, the ionization electron drift velocity and lifetime in liquid argon, as obtained from through-going muon data complete the present report.

  9. A library of MiMICs allows tagging of genes and reversible, spatial and temporal knockdown of proteins in Drosophila

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Nagarkar-Jaiswal, Sonal; Lee, Pei-Tseng; Campbell, Megan E.; Chen, Kuchuan; Anguiano-Zarate, Stephanie; Cantu Gutierrez, Manuel; Busby, Theodore; Lin, Wen-Wen; He, Yuchun; Schulze, Karen L.; et al

    2015-03-31

    Here, we document a collection of ~7434 MiMIC (Minos Mediated Integration Cassette) insertions of which 2854 are inserted in coding introns. They allowed us to create a library of 400 GFP-tagged genes. We show that 72% of internally tagged proteins are functional, and that more than 90% can be imaged in unfixed tissues. Moreover, the tagged mRNAs can be knocked down by RNAi against GFP (iGFPi), and the tagged proteins can be efficiently knocked down by deGradFP technology. The phenotypes associated with RNA and protein knockdown typically correspond to severe loss of function or null mutant phenotypes. Finally, we demonstratemore »reversible, spatial, and temporal knockdown of tagged proteins in larvae and adult flies. This new strategy and collection of strains allows unprecedented in vivo manipulations in flies for many genes. These strategies will likely extend to vertebrates.« less

  10. Issues with Y-STR Profile Frequency Estimation

    E-Print Network [OSTI]

    -chair John Butler (NIST) Ann Gross (MN) Bruce Budowle (FBI) Jill Smerick (FBI) Sam Baechtel (FBI) John) Carl Ladd (CT) Charles Barna (MI) Debbie Figarelli (Phoenix PD) SWGDAM Y-STR Committee http://www.fbi Interpretation Guidelines with Section 5 discussing statistical interpretation http://www.fbi

  11. DC 12m telescope. Preliminary calculations. Investigation of elevation axis position.

    SciTech Connect (OSTI)

    Guarino, V. J.; High Energy Physics

    2009-12-18

    This paper examines some simple calculations of a 2D model of a telescope in order to understand how different design parameters affect the design. For the design of a telescope it is assumed that they need a design that minimizes deflections of the dish and also minimizes the size of the motors and torques needed to rotate in elevation. A common belief is that a lighter dish and minimum counterweight is desirable. However, these calculations show this is not necessarily true. The torque needed for rotation depends on the moment of inertia and if the telescope is balanced about the elevation axis. A light dish with no CW requires that the elevation axis be several meters in front of the dish (8-9m) in order to be balanced. This is not practical from a structural point of view. If the elevation axis is only 2m in front of the dish and there is no counterweight then the telescope will be unbalanced and the toruqes required will be very high - much higher than the torques needed only to overcome inertia. A heavy dish though can act as its own counterweight and the elevation axis only has to be 2-3m in front of the dish in order to achieve a balanced telescope. Also the struts that support the camera from the dish place a load on the dish which will put a bending moment on the dish. This bending moment will deform the dish and require it to be stiffer. A counterweight structure performs two functions. First, it allows the telescope to be balanced about the elevation axis. Second, it applies a force on the dish that opposes the forces from the camera struts, thereby reducing the bending moment and deformations of the dish.

  12. LUNAR SEISMIC PROFILING EXPERIMENT HOUSING AND CHARGE ASSEMBLY

    E-Print Network [OSTI]

    Rathbun, Julie A.

    ATM-1094f LUNAR SEISMIC PROFILING EXPERIMENT HOUSING AND CHARGE ASSEMBLY FOAM TEST REPORT PAGE DATE. R. Lewis, Manager Lunar Seismic Profiling Experiment #12;ATM-1094 I LUNAR SEISMIC PROFILING'MNAR SEISMIC PROFILING EXPERIMENT HOUSING AND CHARGE ASSEMBLY FOAM TEST REPORT .C"l. j_ ..LV~ .L v 7"'% I PAGE

  13. EUROMED Sustainable Connections: 4.1 Community Profile Troianata, Kefalonia, Greece 1 COMMUNITY PROFILE

    E-Print Network [OSTI]

    Zaferatos, Nicholas C.

    EUROMED Sustainable Connections: 4.1 Community Profile ­ Troianata, Kefalonia, Greece 1 COMMUNITY PROFILE Village of Troianata Island of Kefalonia, Greece Kefalonia was named after the mythological figure of the fastest population growth rates in Greece during the 1990s. The present population density is 55 people

  14. Profile of a Cohort A statistical profile of the 1997 CS entry Janet Carter

    E-Print Network [OSTI]

    Kent, University of

    ............................................................ 10 #12; 2 General Entry Qualifications The A­level Entrants Does a higher A­level point score mean1 Profile of a Cohort ­ A statistical profile of the 1997 CS entry Janet Carter Contents General Entry Qualifications A­level Entrants

  15. Natural gas annual 1993 supplement: Company profiles

    SciTech Connect (OSTI)

    Not Available

    1995-02-01

    The Natural Gas Annual provides information on the supply and disposition of natural gas to a wide audience including industry, consumers, Federal and State agencies, and educational institutions. This report, the Natural Gas Annual 1993 Supplement: Company Profiles, presents a detailed profile of 45 selected companies in the natural gas industry. The purpose of this report is to show the movement of natural gas through the various States served by the companies profiled. The companies in this report are interstate pipeline companies or local distribution companies (LDC`s). Interstate pipeline companies acquire gas supplies from company owned production, purchases from producers, and receipts for transportation for account of others. Pipeline systems, service area maps, company supply and disposition data are presented.

  16. Process for forming retrograde profiles in silicon

    DOE Patents [OSTI]

    Weiner, Kurt H. (San Jose, CA); Sigmon, Thomas W. (Phoenix, AZ)

    1996-01-01

    A process for forming retrograde and oscillatory profiles in crystalline and polycrystalline silicon. The process consisting of introducing an n- or p-type dopant into the silicon, or using prior doped silicon, then exposing the silicon to multiple pulses of a high-intensity laser or other appropriate energy source that melts the silicon for short time duration. Depending on the number of laser pulses directed at the silicon, retrograde profiles with peak/surface dopant concentrations which vary from 1-1e4 are produced. The laser treatment can be performed in air or in vacuum, with the silicon at room temperature or heated to a selected temperature.

  17. Smaller cornu ammonis 2-3/dentate gyrus volumes and elevated cortisol in multiple sclerosis patients with depressive symptoms.

    E-Print Network [OSTI]

    2010-01-01

    and elevated cortisol in multiple sclerosis patients withNancy L Sicotte 1,2 Multiple Sclerosis Program, Departmentwords: relapsing-remitting multiple sclerosis – depression –

  18. OPEN POSITION: Entomological Taxonomist and Research Associate Improving our understanding of the elevational biodiversity gradient of Rocky Mountain National Park

    E-Print Network [OSTI]

    Ishida, Yuko

    of the elevational biodiversity gradient of Rocky Mountain National Park: arthropod diversity and conservation Range, including from Rocky Mountain National Park. The taxonomic groups of most interest include

  19. Evidence that chytrids dominate fungal communities in high-elevation soils

    E-Print Network [OSTI]

    Schmidt, Steven K.

    - out the world. In a more focused study of our sites in Colorado, we show that carbon sources reservoirs of undocumented biodiversity (4, 5). High-elevation soils are unique and may be challenging never been characterized (9). A majority of molecular surveys of fungal community com- position have

  20. Combining satellite multispectral image data and a digital elevation model for mapping debris-covered glaciers

    E-Print Network [OSTI]

    Kääb, Andreas

    Combining satellite multispectral image data and a digital elevation model for mapping debris classification alone. Based on the observation of low slope angles for debris-covered glacier tongues, we of automated multispectral classification for clean glacier ice and vegetation with slope information derived

  1. ORIGINAL PAPER Effects of elevated CO2 and soil water content on phytohormone

    E-Print Network [OSTI]

    DeLucia, Evan H.

    ORIGINAL PAPER Effects of elevated CO2 and soil water content on phytohormone transcript induction CO2. A mild reduction in soil water content had no effect on leaf sugars but stimulated the induction and reduced soil water content suppressed the expression of transcripts related to JA and ET gene tran

  2. The earliest stages of ecosystem succession in high-elevation (5000 metres above

    E-Print Network [OSTI]

    Colorado at Boulder, University of

    or vascular plants. Carbon analyses (pyrolysis-gas chromatography/mass spectroscopy) of soil organic matter), recently deglaciated soils S. K. Schmidt1,*, , Sasha C. Reed1,2, , Diana R. Nemergut2,3 , A. Stuart Grandy4. The exposure of `new' soil is particularly apparent at high elevations (5000 metres above sea level

  3. Do fluctuating temperature environments elevate coral thermal T. A. Oliver S. R. Palumbi

    E-Print Network [OSTI]

    Palumbi, Stephen

    REPORT Do fluctuating temperature environments elevate coral thermal tolerance? T. A. Oliver · S. R fluctuating environments on coral thermal toler- ance. We experimentally heat-stressed Acropora hyacinthus, much research has focused on the capacity of corals to acclimatize and/or adapt to different thermal

  4. Elevated Trace Element Concentrations in Southern Toads, Bufo terrestris, Exposed to Coal Combustion Waste

    E-Print Network [OSTI]

    Hopkins, William A.

    Elevated Trace Element Concentrations in Southern Toads, Bufo terrestris, Exposed to Coal, and behavioral abnormalities in amphibians to coal combustion wastes (coal ash). Few studies, however, have determined trace element concentrations in amphibians exposed to coal ash. In the current study we compare

  5. American Journal of Botany 92(8): 12641269. 2005. POLLINATION SUCCESS ACROSS AN ELEVATION AND SEX

    E-Print Network [OSTI]

    Herrera, Carlos M.

    and ecological factors may influence these parameters. I analyzed the consequences of variation in population sex increased with elevation, suggesting that the higher availability of pollen due to the increased proportion in populations with a proportion of females 50%, although both pollination success and natural fruit set

  6. Forest Sensitivity to Elevated Atmospheric CO2 and its Relevance to Carbon Management Richard J. Norby

    E-Print Network [OSTI]

    the airborne fraction of CO2 from fossil fuel combustion, and, therefore, the rate of increase of CO2Forest Sensitivity to Elevated Atmospheric CO2 and its Relevance to Carbon Management Richard J the responses of forest trees to rising concentrations of atmospheric CO2 has for the past two decades been

  7. Stem respiration in tropical forests along an elevation gradient in the Amazon and Andes

    E-Print Network [OSTI]

    Malhi, Yadvinder

    Stem respiration in tropical forests along an elevation gradient in the Amazon and Andes A M A N D metabolism, resulting in the release of carbon dioxide as a by-product. Little is known of how autotrophic respiration components vary across environmental gradients, particularly in tropical ecosystems. Here, we

  8. Lecture 01 -Supplement: Examples of Modeling ## age elevation length mass sex

    E-Print Network [OSTI]

    Rotella, Jay J.

    .87701 9.21 5.3e-11 *** ## age 1.50580 0.05214 28.88 .93 9.2e-11 *** ## age 1.50638 0.05306 28.39 Lecture 01 - Supplement: Examples of Modeling Approaches A dataset head(d) ## age elevation length

  9. Near-Infrared Laser Absorption of Poly(vinyl chloride) at Elevated Temperatures

    E-Print Network [OSTI]

    Van de Ven, James D.

    Near-Infrared Laser Absorption of Poly(vinyl chloride) at Elevated Temperatures James D. Van de Ven, Arthur G. Erdman Mechanical Engineering Department, University of Minnesota, Minneapolis, Minnesota 55305 yields that little work has been done analyzing the relationship between light absorption and temperature

  10. Flow of Fiber-Reinforced Cement Slurries at Elevated Temperatures Y. Wang and C. Meyer

    E-Print Network [OSTI]

    Meyer, Christian

    . Keywords: Non-Newtonian fluids; Fiber suspensions; Oil well cement slurries; Rheology 1. Problem Statement are used for the construction of oil wells as deep as 30,000 ft (9,000 m). The severe performanceFlow of Fiber-Reinforced Cement Slurries at Elevated Temperatures Y. Wang and C. Meyer Dept

  11. Mountain Peak Identification in Visual Content Based on Coarse Digital Elevation Models

    E-Print Network [OSTI]

    Tagliasacchi, Marco

    Mountain Peak Identification in Visual Content Based on Coarse Digital Elevation Models Roman for the identification of mountain peaks in geo-tagged photos. The key tenet is to perform an edge- based matching of the position of mountain peaks with a coarse resolution DEM available in the corresponding ge- ographical area

  12. Polarization modulation infrared reflection absorption spectroscopy for heterogeneous catalytic applications at elevated pressures 

    E-Print Network [OSTI]

    Ozensoy, Emrah

    2005-08-29

    morphologies such as metal nanoparticles deposited on a metal-oxide thin film. In order to achieve a molecular understanding of the properties of CO+NO catalytic reaction at elevated temperatures and pressures on Pd based catalysts, adsorption trends of each...

  13. A Database of Herbaceous Vegetation Responses to Elevated Atmospheric CO2

    E-Print Network [OSTI]

    A Database of Herbaceous Vegetation Responses to Elevated Atmospheric CO2 ORNL/CDIAC-124 NDP-073, which may not be used without his written permission. #12;ORNL/CDIAC-124 NDP-073 A DATABASE Department of Evolution, Ecology, and Organismal Biology The Ohio State University Columbus, Ohio Prepared

  14. Elevated voltage level I.sub.DDQ failure testing of integrated circuits

    DOE Patents [OSTI]

    Righter, Alan W. (Albuquerque, NM)

    1996-01-01

    Burn in testing of static CMOS IC's is eliminated by I.sub.DDQ testing at elevated voltage levels. These voltage levels are at least 25% higher than the normal operating voltage for the IC but are below voltage levels that would cause damage to the chip.

  15. APPLICATION OF DIGITALMULTISPECTRAL IMAGERY TO LITTORAL ZONE SOIL AND ELEVATION MODELING-

    E-Print Network [OSTI]

    Fabrizio, Mary C.

    . The two primary landform zones found within the study area include the coastal beach zone and the dune of longitudinally oriented upland, sandy dunes dissected by very wet marshes. This coastal geomorphology, common between vegetation, soil and elevation data. Upon review, statistics suggested there was association

  16. Catalytic oxidation of CO by platinum group metals: from ultrahigh vacuum to elevated pressures

    E-Print Network [OSTI]

    Goodman, Wayne

    oxidation over platinum group metals has been investigated for some eight decades by many researchersCatalytic oxidation of CO by platinum group metals: from ultrahigh vacuum to elevated pressures A Catalytic oxidation of CO over platinum group metals (Pt, Ir, Rh and Pd) has been the subject of many

  17. THE EFFECT OF WATER TABLE ELEVATION ON ACID MINE DRAINAGE FROM REACTIVE TAILINGS

    E-Print Network [OSTI]

    Aubertin, Michel

    THE EFFECT OF WATER TABLE ELEVATION ON ACID MINE DRAINAGE FROM REACTIVE TAILINGS: A LABORATORY table can be very effective in reducing the production of acid mine drainage. ______________________ 1 Paper presented at the 7th International Conference on Acid Rock Drainage (ICARD), March 26-30, 2006, St

  18. An evaluation of the elevated water table concept using laboratory columns with sulphidic tailings

    E-Print Network [OSTI]

    Aubertin, Michel

    The elevated water table concept is a potentially effective means of reducing acid mine drainage from reactive for controlling acid mine drainage from mine tailings. The laboratory experiments used columns of tailings from acid mine drainage. RESUME La technique de la nappe surélevée est considérée comme un moyen efficace

  19. ORNL/TM-2005/553 The Effect of Elevated Temperature on

    E-Print Network [OSTI]

    Pennycook, Steve

    .4) Prepared for the U.S. Nuclear Regulatory Commission Office of Nuclear Regulatory Research Under Interagency for the U.S. Nuclear Regulatory Commission Office of Nuclear Regulatory Research Under Interagency Agreement materials for elevated- temperature service is presented. Nuclear power plant and general civil engineering

  20. EVLA Memo # 136 EVLA Measurements Close to the Sun: Elevated System

    E-Print Network [OSTI]

    Groppi, Christopher

    EVLA Memo # 136 EVLA Measurements Close to the Sun: Elevated System Temperatures Catherine A ) measurements near the sun at 5 GHz with EVLA antennas. The purpose of the test measurements was to measure the solar contribution to the system temperature as a function of angular distance from the sun. At a given

  1. EVLA Memo # 136 EVLA Measurements Close to the Sun: Elevated System

    E-Print Network [OSTI]

    Groppi, Christopher

    EVLA Memo # 136 EVLA Measurements Close to the Sun: Elevated System Temperatures Catherine A) measurements near the sun at 5 GHz with EVLA antennas. The purpose of the test measurements was to measure the solar contribution to the system temperature as a function of angular distance from the sun. At a given

  2. Water Resource Topics (#1-2) 1. Changes in drought patterns with elevation

    E-Print Network [OSTI]

    Water Resource Topics (#1-2) 1. Changes in drought patterns with elevation Background research. Upconing of salt water into drinking water wells Background research on analytical methods to assess upconing in unconfined and confined aquifers Identify aquifer sector, drinking water wells, and data

  3. Soil microbial activity and N availability with elevated CO2 in Mojave Desert soils

    E-Print Network [OSTI]

    Billings, Sharon A.; Schaeffer, Sean M.

    2004-01-01

    We examined the effects of elevated CO2 on soil nitrogen (N) dynamics in the Mojave Desert by measuring plant N isotope composition (?15N), soil microbial biomass N, soil respiration, resin-available N, and C and N dynamics during soil incubations...

  4. FUSION OF DIGITAL ELEVATION MODELS USING SPARSE REPRESENTATIONS H. Papasaika1

    E-Print Network [OSTI]

    Schindler, Konrad

    FUSION OF DIGITAL ELEVATION MODELS USING SPARSE REPRESENTATIONS H. Papasaika1 , E. Kokiopoulou2 , E Science and Engineering, EPFL, Switzerland Working Groups I/2, III/1, III/4, III/5 KEY WORDS: DEMs, fusion acquisition technology, the processing chain, and the characteristics of the terrain. DEM fusion aims

  5. Original Contribution Elevated Lung Cancer in Younger Adults and Low Concentrations of Arsenic

    E-Print Network [OSTI]

    California at Berkeley, University of

    Original Contribution Elevated Lung Cancer in Younger Adults and Low Concentrations of Arsenic-term effects of arsenic. We performed a case-control study of lung cancer from 2007 to 2010 in areas or more years ago resulted in odds ratios for lung cancer of 1.00, 1.43 (90% confidence interval: 0.82, 2

  6. Icelandic rhythmics: Annual modulation of land elevation and plate spreading by snow load

    E-Print Network [OSTI]

    Grapenthin, Ronni

    Icelandic rhythmics: Annual modulation of land elevation and plate spreading by snow load Ronni to annual snow load in Iceland. The load is modeled using Green's functions for an elastic halfspace and a simple sinusoidal load history on Iceland's four largest ice caps. We derive E = 40 ± 15 GPa as a minimum

  7. Volume and mass balance changes of ice caps in Iceland deduced from elevation data and

    E-Print Network [OSTI]

    Berthier, Etienne

    Volume and mass balance changes of ice caps in Iceland deduced from elevation data and in-situ mass Guðmundsson, Þórdís Högnadóttir Institute of Earth Sciences, University of Iceland (IES) Etienne Berthier LEGOS, Toulouse, France Tómas Jóhannesson, Oddur Sigurðsson, Þorsteinn Þorsteinsson The Icelandic

  8. Using satellites to investigate the sensitivity of longwave downward radiation to water vapor at high elevations

    E-Print Network [OSTI]

    at high elevations Catherine M. Naud,1 James R. Miller,2 and Chris Landry3 Received 22 September 2011 is insufficient to do so. Citation: Naud, C. M., J. R. Miller, and C. Landry (2012), Using satellites to climate change [e.g., Diaz and Bradley, 1997; Liu and Chen, 2000; Rangwala et al., 2009]. In some

  9. CARIBBEAN DIGITAL ELEVATION MODELS Coastal Models Supporting our Nation's Needs through Science and Technology

    E-Print Network [OSTI]

    natural resources. Data identified as coming from the NOAA National Geophysical Data Center are provided, coastal managers, and policy makers in effectively managing marine ecosystems and coastal resources;DIGITAL ELEVATION MODEL PuertoRicoIsland #12;http://www.ngdc.noaa.gov/mgg/coastal/ dem.info

  10. Author's personal copy Antioxidant capacity reduced in scallions grown under elevated CO2

    E-Print Network [OSTI]

    Paré, Paul W.

    Author's personal copy Antioxidant capacity reduced in scallions grown under elevated CO2 was used as a model plant to study the impact of a range of CO2 concentrations and light intensities in controlled environmental chambers under a combination of 3 CO2 concentrations of 400, 1200 and 4000 lmol mol

  11. Elevated CO2 levels affect development, motility, and fertility and extend life

    E-Print Network [OSTI]

    Morimoto, Richard

    Elevated CO2 levels affect development, motility, and fertility and extend life span August 5, 2008) Hypercapnia (high CO2 levels) occurs in a number of lung diseases and it is associated the response to nonanesthetic CO2 levels and show that levels exceeding 9% induce aberrant motility

  12. EFFECTS OF ELEVATED CO2 ON ROOT FUNCTION AND SOIL RESPIRATION IN A MOJAVE DESERT ECOSYSTEM

    SciTech Connect (OSTI)

    Nowak, Robert S.

    2007-12-19

    Increases in atmospheric CO{sub 2} concentration during the last 250 years are unequivocal, and CO{sub 2} will continue to increase at least for the next several decades (Houghton et al. 2001, Keeling & Whorf 2002). Arid ecosystems are some of the most important biomes globally on a land surface area basis, are increasing in area at an alarming pace (Dregne 1991), and have a strong coupling with regional climate (Asner & Heidebrecht 2005). These water-limited ecosystems also are predicted to be the most sensitive to elevated CO{sub 2}, in part because they are stressful environments where plant responses to elevated CO{sub 2} may be amplified (Strain & Bazzaz 1983). Indeed, all C{sub 3} species examined at the Nevada Desert FACE Facility (NDFF) have shown increased A{sub net} under elevated CO{sub 2} (Ellsworth et al. 2004, Naumburg et al. 2003, Nowak et al. 2004). Furthermore, increased shoot growth for individual species under elevated CO{sub 2} was spectacular in a very wet year (Smith et al. 2000), although the response in low to average precipitation years has been smaller (Housman et al. 2006). Increases in perennial cover and biomass at the NDFF are consistent with long term trends in the Mojave Desert and elsewhere in the Southwest, indicating C sequestration in woody biomass (Potter et al. 2006). Elevated CO{sub 2} also increases belowground net primary production (BNPP), with average increases of 70%, 21%, and 11% for forests, bogs, and grasslands, respectively (Nowak et al. 2004). Although detailed studies of elevated CO{sub 2} responses for desert root systems were virtually non-existent prior to our research, we anticipated that C sequestration may occur by desert root systems for several reasons. First, desert ecosystems exhibit increases in net photosynthesis and primary production at elevated CO{sub 2}. If large quantities of root litter enter the ecosystem at a time when most decomposers are inactive, significant quantities of carbon may be stored belowground in relatively recalcitrant forms. Indeed, a model-based analysis predicted that the arid/semiarid southwestern bioclimatic region had one of the highest rates of net carbon storage in the United States over the past century (Schimel et al. 2000). Second, root systems of desert plants are often extensive (Foxx et al. 1984, Hartle et al. 2006) with relatively large proportions of roots deep in the soil (Schenk & Jackson 2002). Thus, an understanding of belowground processes in desert ecosystems provides information on the potential for terrestrial carbon sequestration in desert ecosystems.

  13. The Average Mass Profile of Galaxy Clusters

    E-Print Network [OSTI]

    R. G. Carlberg; H. K. C. Yee; E. Ellingson; S. L. Morris; R. Abraham; P. Gravel; C. J. Pritchet; T. Smecker-Hane; F. D. A. Hartwick; J. E. Hesser; J. B. Hutchings; J. B. Oke

    1997-05-23

    The average mass density profile measured in the CNOC cluster survey is well described with the analytic form rho(r)=A/[r(r+a_rho)^2], as advocated on the basis on n-body simulations by Navarro, Frenk & White. The predicted core radii are a_rho=0.20 (in units of the radius where the mean interior density is 200 times the critical density) for an Omega=0.2 open CDM model, or a_rho=0.26 for a flat Omega=0.2 model, with little dependence on other cosmological parameters for simulations normalized to the observed cluster abundance. The dynamically derived local mass-to-light ratio, which has little radial variation, converts the observed light profile to a mass profile. We find that the scale radius of the mass distribution, 0.20<= a_rho <= 0.30 (depending on modeling details, with a 95% confidence range of 0.12-0.50), is completely consistent with the predicted values. Moreover, the profiles and total masses of the clusters as individuals can be acceptably predicted from the cluster RMS line-of-sight velocity dispersion alone. This is strong support of the hierarchical clustering theory for the formation of galaxy clusters in a cool, collisionless, dark matter dominated universe.

  14. INTRODUCTION Weathering profiles are complex open geo-

    E-Print Network [OSTI]

    Derry, Louis A.

    . HAWAII CHRONOSEQUENCEAND CLIMATE GRADIENT Our data were collected as part of an ongoing), and 4100 ka (Kauai).All soil profiles were sampled on primary shield-volcano surfaces, where physical ka Hawi series lava flows on the leeward side of Kohala Mountain, Hawaii (Chadwick et al., 1994

  15. Performance Profiles of Major Energy Producers

    Reports and Publications (EIA)

    2011-01-01

    The information and analyses in Performance Profiles of Major Energy Producers is intended to provide a critical review, and promote an understanding, of the possible motivations and apparent consequences of investment decisions made by some of the largest corporations in the energy industry.

  16. Suspended Solids Profiler Shop Test Report

    SciTech Connect (OSTI)

    STAEHR, T.W.

    2000-01-19

    The Suspended Solids Profiler (SSP) Instrument is planned to be installed in the AZ-101 tank to measure suspended solids concentrations during mixer pump testing. The SSP sensor uses a reflectance measurement principle to determine the suspended solids concentrations. The purpose of this test is to provide a documented means of verifying that the functional components of the SSP operate properly.

  17. utility functions scaling profiles utility-fair

    E-Print Network [OSTI]

    Chang, Shih-Fu

    bandwidth utility functions scaling profiles utility-fair I. INTRODUCTION The emerging MPEG-4 video. This can result in a significant increase in the utilization of network capacity [1]. These techniques. Bandwidth utility functions [9] can be used to characterize an application's capability to adapt over

  18. REVIEW ARTICLE Profile likelihood in systems biology

    E-Print Network [OSTI]

    Timmer, Jens

    REVIEW ARTICLE Profile likelihood in systems biology Clemens Kreutz1,2 , Andreas Raue1,3 , Daniel for Advanced Studies (FRIAS), University of Freiburg, Germany 3 Institute of Bioinformatics and Systems Biology of Freiburg, Germany 5 BIOSS Centre for Biological Signalling Studies, University of Freiburg, Germany

  19. Yet Another Mathematical Approach to Geographic Profiling

    E-Print Network [OSTI]

    Morrow, James A.

    3 Known Prediction Schemes 7 3.1 O'Leary's New Mathematical Approach to Criminal Profiling . 7 3 . . . . . . . . . . . . 8 3.1.3 Simple Models for Offender Behavior . . . . . . . . . . 9 3.1.4 O'Leary's General Model.S. Census data . . . . . . . . . 19 3 Prediction of home base location, demonstrating O'Leary's model

  20. Route profile analysis system and method

    DOE Patents [OSTI]

    Mullenhoff, D.J.; Wilson, S.W.

    1982-07-29

    A system for recording terrain profile information is disclosed. The system accurately senses incremental distances traveled by a vehicle along with vehicle inclination, recording both with elapsed time. The incremental distances can subsequently be differentiated with respect to time to obtain acceleration. The computer acceleration can then be used to correct the sensed inclination.

  1. Adaptive User Profiles in Pervasive Advertising Environments

    E-Print Network [OSTI]

    Adaptive User Profiles in Pervasive Advertising Environments Florian Alt1 , Moritz Balz2 , Stefanie advertising environments try to provide more effi- cient ads by targeting costumers based on their interests. We implemented an advertising platform to simulate an advertising environment and present adaptive

  2. Confinement and the safety factor profile

    SciTech Connect (OSTI)

    Batha, S.H.; Levinton, F.M.; Scott, S.D.

    1995-12-01

    The conjecture that the safety factor profile, q(r), controls the improvement in tokamak plasmas from poor confinement in the Low (L-) mode regime to improved confinement in the supershot regime has been tested in two experiments on the Tokamak Fusion Test Reactor (TFTR). First, helium was puffed into the beam-heated phase of a supershot discharge which induced a degradation from supershot to L-mode confinement in about 100 msec, far less than the current relaxation time. The q and shear profiles measured by a motional Stark effect polarimeter showed little change during the confinement degradation. Second, rapid current ramps in supershot plasmas altered the q profile, but were observed not to change significantly the energy confinement. Thus, enhanced confinement in supershot plasmas is not due to a particular q profile which has enhanced stability or transport properties. The discharges making a continuous transition between supershot and L-mode confinement were also used to test the critical-electron-temperature-gradient transport model. It was found that this model could not reproduce the large changes in electron and ion temperature caused by the change in confinement.

  3. Monkey Gamer: Automatic Profiling of Android Games

    E-Print Network [OSTI]

    1 Monkey Gamer: Automatic Profiling of Android Games Javier Mari´an Santos, Simin Nadjm and their interaction level. We present Monkey Gamer, a software to automatically play a large class of Android games and by human players, for three of the most popular Android games. We evaluate the performance of the Monkey

  4. Triangular Profile Imprint Molds in Nanograting Fabrication

    E-Print Network [OSTI]

    Triangular Profile Imprint Molds in Nanograting Fabrication Zhaoning Yu* and Stephen Y. Chou line widths and smooth edges. A wet chemical etching process is employed during mold preparation abandons the use of mold features with vertical sidewalls. Instead, it uses grating molds with triangle

  5. A study of muon neutrino disappearance with the MINOS detectors and the NuMI neutrino beam

    SciTech Connect (OSTI)

    Marshall, John Stuart; /Cambridge U.

    2008-06-01

    This thesis presents the results of an analysis of {nu}{sub {mu}} disappearance with the MINOS experiment, which studies the neutrino beam produced by the NuMI facility at Fermi National Accelerator Laboratory. The rates and energy spectra of charged current {nu}{sub {mu}} interactions are measured in two similar detectors, located at distances of 1 km and 735 km along the NuMI beamline. The Near Detector provides accurate measurements of the initial beam composition and energy, while the Far Detector is sensitive to the effects of neutrino oscillations. The analysis uses data collected between May 2005 and March 2007, corresponding to an exposure of 2.5 x 10{sup 20} protons on target. As part of the analysis, sophisticated software was developed to identify muon tracks in the detectors and to reconstruct muon kinematics. Events with reconstructed tracks were then analyzed using a multivariate technique to efficiently isolate a pure sample of charged current {nu}{sub {mu}} events. An extrapolation method was also developed, which produces accurate predictions of the Far Detector neutrino energy spectrum, based on data collected at the Near Detector. Finally, several techniques to improve the sensitivity of an oscillation measurement were implemented, and a full study of the systematic uncertainties was performed. Extrapolating from observations at the Near Detector, 733 {+-} 29 Far Detector events were expected in the absence of oscillations, but only 563 events were observed. This deficit in event rate corresponds to a significance of 4.3 standard deviations. The deficit is energy dependent and clear distortion of the Far Detector energy spectrum is observed. A maximum likelihood analysis, which fully accounts for systematic uncertainties, is used to determine the allowed regions for the oscillation parameters and identifies the best fit values as {Delta}m{sub 32}{sup 2} = 2.29{sub -0.14}{sup +0.14} x 10{sup -3} eV{sup 2} and sin{sup 2} 2{theta}{sub 23} > 0.953 (68% confidence level). The models of neutrino decoherence and decay are disfavored at the 5.0{sigma} and 3.2{sigma} levels respectively, while the no oscillation model is excluded at the 9.4{sigma} level.

  6. Overstory community composition and elevated atmospheric CO2 and O3 modify understory biomass production and nitrogen acquisition

    E-Print Network [OSTI]

    understood, although evidence suggests that elevated CO2 will alleviate some of the negative effects. Our objective was to document the effects of elevated atmospheric CO2 and O3 on understory species biomass was harvested in June of 2004 for productivity, N, and 15N measurements, and photosynthetically

  7. Environmental effects on distributions of culturable soil oligotrophic bacteria along an elevational gradient in the Chihuahuan Desert

    E-Print Network [OSTI]

    Strauss, Richard E.

    an elevational gradient in the Chihuahuan Desert James H. Campbell*, John C. Zak, Randall M. Jeter, Richard E from five sites along an elevational and vegetational gradient within Big Bend National Park during the first stressors to be investigated. Microbes capable of metabolism at low concentra- tions of carbon

  8. T-567: Linux Kernel Buffer Overflow in ldm_frag_add() May Let Local Users Gain Elevated Privileges

    Broader source: Energy.gov [DOE]

    A vulnerability was reported in the Linux Kernel. A local user may be able to obtain elevated privileges on the target system. A physically local user can connect a storage device with a specially crafted LDM partition table to trigger a buffer overflow in the ldm_frag_add() function in 'fs/partitions/ldm.c' and potentially execute arbitrary code with elevated privileges.

  9. An experimental and kinetic study of syngas/air combustion at elevated temperatures and the effect of water addition

    E-Print Network [OSTI]

    Qiao, Li

    . Introduction Synthetic gas (syngas) is a mixture of carbon monoxide and hydrogen in various compositionsAn experimental and kinetic study of syngas/air combustion at elevated temperatures and the effect 20 December 2011 Keywords: Syngas combustion Elevated temperatures Water addition Laminar flame speed

  10. Vegetation patterns of Pine Canyon, Big Bend National Park, Texas, in relation to elevation and slope aspect 

    E-Print Network [OSTI]

    Harris, Bryan Joseph

    1997-01-01

    Data on the woody vegetation of Pine Canyon, Big Bend National Park, Texas was gathered on an elevational gradient from 1250 m to 2000 m elevation using the point-centered quarter method. Sampling was conducted at 12 sites at 1250 m, 1500 m, 1625 m...

  11. Effect of elevated CO2 and N fertilisation on soil nematode abundance and diversity in a wheat field

    E-Print Network [OSTI]

    Neher, Deborah A.

    Author's personal copy Effect of elevated CO2 and N fertilisation on soil nematode abundance). The soil food chain response to elevated CO2 can indicate the changes in soil ecological processes s t r a c t An experimental platform of free-air CO2 enrichment (FACE) was established in mid June

  12. Inter and intra-specific variation in photosynthetic acclimation response to long term exposure of elevated carbon dioxide

    SciTech Connect (OSTI)

    Wilkinson, M. [Univ. of Essex, Colchester (United Kingdom); [Writtle Coll. (United Kingdom)

    1996-08-01

    The response of intra and interspecific variation in photosynthetic acclimation to growth at elevated atmospheric CO{sub 2} concentration (600{micro}mol mol-l) in six important grassland species was investigated. Plants were grown in a background sward of Lolium perenne and measurements were made after four years of growth at elevated C{sub a}. Elevated CO{sub 2} was maintained using a FACE (Free-Air Carbon Enrichment) system. Significant intra and interspecific variation in acclimation response was demonstrated. The response of adaxial and abaxial stomatal conductance to elevated CO{sub 2} was also investigated. The stomatal conductance of both the adaxial and abaxial leaf surfaces was found to be reduced by elevated C{sub a}. Significant asymmetric responses in stomatal conductance was demonstrated in D. glomerata and T. pratense. Analysis of stomatal indices and densities indicated that the observed reductions in stomatal conductance were probably the result of changes in stomatal aperture.

  13. Tropical Cloud Properties and Radiative Heating Profiles

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Mather, James

    2008-01-15

    We have generated a suite of products that includes merged soundings, cloud microphysics, and radiative fluxes and heating profiles. The cloud microphysics is strongly based on the ARM Microbase value added product (Miller et al., 2003). We have made a few changes to the microbase parameterizations to address issues we observed in our initial analysis of the tropical data. The merged sounding product is not directly related to the product developed by ARM but is similar in that it uses the microwave radiometer to scale the radiosonde column water vapor. The radiative fluxes also differ from the ARM BBHRP (Broadband Heating Rate Profile) product in terms of the radiative transfer model and the sampling interval.

  14. The elliptical power law profile lens

    E-Print Network [OSTI]

    Tessore, Nicolas

    2015-01-01

    The deflection, potential, shear and magnification of a gravitational lens following an elliptical power law mass model are investigated. This mass model is derived from the circular power law profile through a rescaling of the axes, similar to the case of a singular isothermal ellipsoid. The resulting deflection can be calculated explicitly and given in terms of the Gaussian hypergeometric function. Analytic expressions for the remaining lensing properties are found as well. Because the power law profile lens contains a number of well-known lens models as special cases, the equivalence of the new expressions with known results is checked. Finally, it is shown how these results naturally lead to a fast and accurate numerical scheme for computing the deflection and other lens quantities, making this method a useful tool for realistically modelling observed lenses.

  15. Optimizing the ATLAS code with different profilers

    E-Print Network [OSTI]

    Kama, S; The ATLAS collaboration

    2013-01-01

    After the current maintenance period, the LHC will provide higher energy collisions with increased luminosity. In order to keep up with these higher rates, ATLAS software needs to speed up substantially. However, ATLAS code is composed of approximately 4M lines, written by many different programmers with different backgrounds, which makes code optimisation a challenge. To help with this effort different profiling tools and techniques are being used. These include well known tools, such as the Valgrind suite and Intel Amplifier; less common tools like PIN, PAPI, and GOODA; as well as techniques such as library interposing. In this talk we will mainly focus on PIN tools and GOODA. PIN is a dynamic binary instrumentation tool which can obtain statistics such as call counts, instruction counts and interrogate functions' arguments. It has been used to obtain CLHEP Matrix profiles, operations and vector sizes for linear algebra calculations which has provided the insight necessary to achieve significant performance...

  16. Tropical Cloud Properties and Radiative Heating Profiles

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Mather, James

    We have generated a suite of products that includes merged soundings, cloud microphysics, and radiative fluxes and heating profiles. The cloud microphysics is strongly based on the ARM Microbase value added product (Miller et al., 2003). We have made a few changes to the microbase parameterizations to address issues we observed in our initial analysis of the tropical data. The merged sounding product is not directly related to the product developed by ARM but is similar in that it uses the microwave radiometer to scale the radiosonde column water vapor. The radiative fluxes also differ from the ARM BBHRP (Broadband Heating Rate Profile) product in terms of the radiative transfer model and the sampling interval.

  17. Structure Profile by a Model of Precipitation

    E-Print Network [OSTI]

    Wang, Zhenggang

    2009-01-01

    The organizational structure of a network is investigated with a simulated precipitation model which does not make use of prior knowledge about the community structure of the network. The result is presented as a structure profile through which various definitions of communities can be applied for specific applications. The simulated precipitation model performs the grouping of nodes so that nodes belonging to the same 'community' automatically aggregate, thereby revealing regions of the adjacency matrix with denser interconnections. The process is analogous to massive particles precipitating towards the lower potential layer. Without loss of the infrastructure information, a community structure profile of a network can be obtained as the ground state of the Hamiltonian. The method is also applicable to directed and weighted networks.

  18. Host and pathogen transcriptional profiles of acute Brucella melitensis infection 

    E-Print Network [OSTI]

    Rossetti, Carlos Alberto

    2009-05-15

    The parallel gene expression profiles of Brucella melitensis and the host have not been elaborated. In this study, I analyze and discuss the transcriptional profiles of B. melitensis invasive-associated genes, the expression ...

  19. Improving ozone profile retrieval from spaceborne UV backscatter

    E-Print Network [OSTI]

    Haak, Hein

    Chapter 2 Improving ozone profile retrieval from spaceborne UV backscatter spectrometers using convergence behaviour diagnostics Abstract The Ozone Profile Algorithm (OPERA), developed at KNMI, retrieves the vertical ozone distribution from nadir spectral satellite measurements of back scattered sunlight

  20. Building America Top Innovations 2013 Profile - Zero Energy-Ready...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Building America Top Innovations 2013 Profile - Zero Energy-Ready Single-Family Homes Building America Top Innovations 2013 Profile - Zero Energy-Ready Single-Family Homes Many...

  1. Building America Top Innovations 2013 Profile - Zero Energy-Ready...

    Energy Savers [EERE]

    Top Innovations 2013 Profile - Zero Energy-Ready Single-Family Homes Building America Top Innovations 2013 Profile - Zero Energy-Ready Single-Family Homes Many Building America...

  2. Biomolecular free energy profiles by a shootingumbrella sampling protocol, ``BOLAS''

    E-Print Network [OSTI]

    Schlick, Tamar

    Biomolecular free energy profiles by a shootingÕumbrella sampling protocol, ``BOLAS'' Ravi an efficient technique for computing free energies corresponding to conformational transitions in complex. This makes possible computation of free energy profiles along complex reaction coordinates for biomolecular

  3. UNIVERSITT AUGSBURG A UML profile and transformation rules

    E-Print Network [OSTI]

    Bauer, Bernhard

    .1 UML 2.0 ..................................................................................................22 4 A UML 2.0 profile for our meta-model .......................................................27 5- 1 - UNIVERSITÄT AUGSBURG A UML profile and transformation rules for semantic web services Florian

  4. ORNL/TM-2009/110 Profile of World Uranium

    E-Print Network [OSTI]

    Pennycook, Steve

    ORNL/TM-2009/110 Profile of World Uranium Enrichment Programs--2009 April 2009 Prepared by M. D PROFILE OF WORLD URANIUM ENRICHMENT PROGRAMS--2009 M. D. Laughter Date Published: April 2009 This work

  5. Controlled ion implant damage profile for etching

    DOE Patents [OSTI]

    Arnold, Jr., George W. (Tijeras, NM); Ashby, Carol I. H. (Edgewood, NM); Brannon, Paul J. (Albuquerque, NM)

    1990-01-01

    A process for etching a material such as LiNbO.sub.3 by implanting ions having a plurality of different kinetic energies in an area to be etched, and then contacting the ion implanted area with an etchant. The various energies of the ions are selected to produce implant damage substantially uniformly throughout the entire depth of the zone to be etched, thus tailoring the vertical profile of the damaged zone.

  6. State Electricity Profiles | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page| Open Energy Information Serbia-Enhancing CapacityVectren) Jump to:SpillDavid,EnergybyBiomassManufacturingProfiles

  7. Comparative performance of geopolymers made with metakaolin and fly ash after exposure to elevated temperatures

    SciTech Connect (OSTI)

    Kong, Daniel L.Y.; Sanjayan, Jay G. Sagoe-Crentsil, Kwesi

    2007-12-15

    This paper presents the results of a study on the effect of elevated temperatures on geopolymers manufactured using metakaolin and fly ash of various mixture proportions. Both types of geopolymers (metakaolin and fly ash) were synthesized with sodium silicate and potassium hydroxide solutions. The strength of the fly ash-based geopolymer increased after exposure to elevated temperatures (800 deg. C). However, the strength of the corresponding metakaolin-based geopolymer decreased after similar exposure. Both types of geopolymers were subjected to thermogravimetric, scanning electron microscopy and mercury intrusion porosimetry tests. The paper concludes that the fly ash-based geopolymers have large numbers of small pores which facilitate the escape of moisture when heated, thus causing minimal damage to the geopolymer matrix. On the other hand, metakaolin geopolymers do not possess such pore distribution structures. The strength increase in fly ash geopolymers is also partly attributed to the sintering reactions of un-reacted fly ash particles.

  8. Sun-relative pointing for dual-axis solar trackers employing azimuth and elevation rotations.

    SciTech Connect (OSTI)

    Riley, Daniel M.; Hansen, Clifford W.

    2014-04-01

    Dual axis trackers employing azimuth and elevation rotations are common in the field of photovoltaic (PV) energy generation. Accurate sun-tracking algorithms are widely available. However, a steering algorithm has not been available to accurately point the tracker away from the sun such that a vector projection of the sun beam onto the tracker face falls along a desired path relative to the tracker face. We have developed an algorithm which produces the appropriate azimuth and elevation angles for a dual axis tracker when given the sun position, desired angle of incidence, and the desired projection of the sun beam onto the tracker face. Development of this algorithm was inspired by the need to accurately steer a tracker to desired sun-relative positions in order to better characterize the electro-optical properties of PV and CPV modules.

  9. ARM - Midlatitude Continental Convective Clouds Experiment (MC3E): Multi-Frequency Profilers, 449 MHz Profiler(williams-449_prof)

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Williams, Christopher; Jensen, Mike

    2012-11-06

    This data was collected by the NOAA 449-MHz and 2.8-GHz profilers in support of the Department of Energy (DOE) and NASA sponsored Mid-latitude Continental Convective Cloud Experiment (MC3E). The profiling radars were deployed in Northern Oklahoma at the DOE Atmospheric Radiation Mission (ARM) Southern Great Plans (SGP) Central Facility from 22 April through 6 June 2011. NOAA deployed three instruments: a Parsivel disdrometer, a 2.8-GHz profiler, and a 449-MHz profiler. The parasivel provided surface estimates of the raindrop size distribution and is the reference used to absolutely calibrate the 2.8 GHz profiler. The 2.8-GHz profiler provided unattenuated reflectivity profiles of the precipitation. The 449-MHz profiler provided estimates of the vertical air motion during precipitation from near the surface to just below the freezing level. By using the combination of 2.8-GHz and 449-MHz profiler observations, vertical profiles of raindrop size distributions can be retrieved. The profilers are often reference by their frequency band: the 2.8-GHz profiler operates in the S-band and the 449-MHz profiler operates in the UHF band. The raw observations are available as well as calibrated spectra and moments. This document describes how the instruments were deployed, how the data was collected, and the format of the archived data.

  10. ARM - Midlatitude Continental Convective Clouds Experiment (MC3E): Multi-Frequency Profilers, 449 MHz Profiler(williams-449_prof)

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Williams, Christopher; Jensen, Mike

    This data was collected by the NOAA 449-MHz and 2.8-GHz profilers in support of the Department of Energy (DOE) and NASA sponsored Mid-latitude Continental Convective Cloud Experiment (MC3E). The profiling radars were deployed in Northern Oklahoma at the DOE Atmospheric Radiation Mission (ARM) Southern Great Plans (SGP) Central Facility from 22 April through 6 June 2011. NOAA deployed three instruments: a Parsivel disdrometer, a 2.8-GHz profiler, and a 449-MHz profiler. The parasivel provided surface estimates of the raindrop size distribution and is the reference used to absolutely calibrate the 2.8 GHz profiler. The 2.8-GHz profiler provided unattenuated reflectivity profiles of the precipitation. The 449-MHz profiler provided estimates of the vertical air motion during precipitation from near the surface to just below the freezing level. By using the combination of 2.8-GHz and 449-MHz profiler observations, vertical profiles of raindrop size distributions can be retrieved. The profilers are often reference by their frequency band: the 2.8-GHz profiler operates in the S-band and the 449-MHz profiler operates in the UHF band. The raw observations are available as well as calibrated spectra and moments. This document describes how the instruments were deployed, how the data was collected, and the format of the archived data.

  11. Advanced interferometric profile measurements through refractive media

    SciTech Connect (OSTI)

    Koev, Stephan T.; Ghodssi, Reza [MEMS Sensors and Actuators Laboratory (MSAL), Department of Electrical and Computer Engineering, Institute for Systems Research, University of Maryland, College Park, Maryland 20742 (United States)

    2008-09-15

    Optical profilers are valuable tools for the characterization of microelectromechanical systems (MEMSs). They use phase sifting interferometry (PSI) or vertical scanning interferometry to measure the topography of microscale structures with nanometer resolution. However, for many emerging MEMS applications, the sample needs to be imaged while placed in a liquid or in a package with a glass window. The increased refractive index of the transparent medium degrades the interference image contrast and prevents any measurement of the sample. We report on the modification of a Veeco NT1100 optical profiler to enable PSI measurements through refractive media. This approach can be applied to any other optical profiler with PSI capability. The modification consists in replacing the original illumination source with a custom-built narrow linewidth source, which increases the coherence length of the light and the contrast of the interference image. We present measurements taken with the modified configuration on samples covered with 3 mm water or 500 {mu}m glass, and we compare them to measurements of uncovered samples. We show that the measurement precision is only slightly reduced by the water and glass, and that it is still sufficiently high for typical MEMS applications. The described method can be readily used for measuring through other types and thicknesses of refractive materials.

  12. The H? profiles of Be shell stars

    SciTech Connect (OSTI)

    Silaj, J.; Jones, C. E.; Sigut, T. A. A.; Tycner, C.

    2014-11-01

    A new set of theoretical H? emission line profiles of Be stars has been computed using the code BERAY, which solves the transfer equation along a series of rays passing through the star+disk system, representing an improved treatment over earlier work done by the authors. The new profiles were compared with the previous work, and general trends (such as line profile shapes and correlations between line equivalent widths as a function of initial density ?{sub 0} and power law index n) were recovered. Additionally, BERAY was employed to model the spectra of eight well-known Be shell stars. Some degeneracy was found in the choice of model parameters, highlighting the need to employ alternate observables to constrain the models. However, the inclination angle of the model seemed relatively insensitive to the choices of other parameters, and we show that, with our models, only a very small range of inclination angles can adequately reproduce the observations. Five of our eight targets were found to have inclination angles of 70° or higher, and two more were found to have inclination angles of 67° and 65°. The observation of one target—4 Aquilae—could only be reproduced by models created at an inclination angle of approximately 45°.

  13. Foster-Glocester Regional School District (Rhode Island) - Financing Profile

    SciTech Connect (OSTI)

    none,

    2008-12-01

    This document is an EnergySmart Schools Financing Profile of Foster-Glocester Regional School District in Rhode Island

  14. An experimental comparison of current viscoplastic constitutive models at elevated temperature 

    E-Print Network [OSTI]

    James, George Henry

    1986-01-01

    AN EXPERIMENTAL COMPARISON OF CURRENT VISCOPLASTIC CONSTITUTIVE MODELS AT ELEVATED TEMPERATURE A Thesis by GEORGE HENRY JAMES III Submitted to the Graduate College of Texas ASM University in partial fulfillment of the requirements..., And Rhode's Model. Bodner's Anisotropic Model. Miller's Model. Walker's Exponential Model. APPENDIX C - AUXILIARY MODEL RESULTS. APPENDIX D EXPERIMENTAL COMPUTER PROGRAMS. VITA. 127 137 137 139 143 144 147 154 176 217 LIST OF TABLES Table...

  15. Spatial disaggregation of satellite-derived irradiance using a high-resolution digital elevation model

    SciTech Connect (OSTI)

    Ruiz-Arias, Jose A.; Tovar-Pescador, Joaquin; Cebecauer, Tomas; Suri, Marcel

    2010-09-15

    Downscaling of the Meteosat-derived solar radiation ({proportional_to}5 km grid resolution) is based on decomposing the global irradiance and correcting the systematic bias of its components using the elevation and horizon shadowing that are derived from the SRTM-3 digital elevation model (3 arc sec resolution). The procedure first applies the elevation correction based on the difference between coarse and high spatial resolution. Global irradiance is split into direct, diffuse circumsolar and diffuse isotropic components using statistical models, and then corrections due to terrain shading and sky-view fraction are applied. The effect of reflected irradiance is analysed only in the theoretical section. The method was applied in the eastern Andalusia, Spain, and the validation was carried out for 22 days on April, July and December 2006 comparing 15-min estimates of the satellite-derived solar irradiance and observations from nine ground stations. Overall, the corrections of the satellite estimates in the studied region strongly reduced the mean bias of the estimates for clear and cloudy days from roughly 2.3% to 0.4%. (author)

  16. Sling-on-a-Ring: Structure for an elevator to LEO

    E-Print Network [OSTI]

    Andrew Meulenberg; Timothy Poston

    2015-04-22

    Various proposed space elevators may bypass the financial and environmental limits on rocket technology, but all have their own problems. A Low-Earth-Orbit, LEO, rotovator-based space-elevator version called 'sling-on-a-ring' may overcome them. This mass-lifting system uses the spatial stability of an orbital ring, accessorized for transfer and storage of momentum and electrical power. A high-tensile-strength equatorial circum-terra loop of colossal-carbon tube, CCT, fiber has solar-power and station-keeping units and rotating sling modules. Long sling assemblies, ~600 km, periodically descend into the atmosphere to ~13 km. At perigee, the sling rotational tip velocity almost cancels the orbital-ring velocity relative to Earth surface. Split-second timing detaches a ~10 ton payload from an ordinary aircraft and jerks it into space by sling momentum, with the proven specific strength of CCTs now under development. This system eliminates the immense mass in space of other space-elevator systems, but needs extremely long (~100km) compressive members. Conceptual analysis for mass reduction of these structures is the subject of this paper.

  17. Sling-on-a-Ring: Structure for an elevator to LEO

    E-Print Network [OSTI]

    Meulenberg, Andrew

    2015-01-01

    Various proposed space elevators may bypass the financial and environmental limits on rocket technology, but all have their own problems. A Low-Earth-Orbit, LEO, rotovator-based space-elevator version called 'sling-on-a-ring' may overcome them. This mass-lifting system uses the spatial stability of an orbital ring, accessorized for transfer and storage of momentum and electrical power. A high-tensile-strength equatorial circum-terra loop of colossal-carbon tube, CCT, fiber has solar-power and station-keeping units and rotating sling modules. Long sling assemblies, ~600 km, periodically descend into the atmosphere to ~13 km. At perigee, the sling rotational tip velocity almost cancels the orbital-ring velocity relative to Earth surface. Split-second timing detaches a ~10 ton payload from an ordinary aircraft and jerks it into space by sling momentum, with the proven specific strength of CCTs now under development. This system eliminates the immense mass in space of other space-elevator systems, but needs extre...

  18. Speeding up Ozone Profile Retrieval using Machine Learning Techniques

    E-Print Network [OSTI]

    Emmerich, Michael

    Speeding up Ozone Profile Retrieval using Machine Learning Techniques L.M. Strijbosch April 25 to the process of ozone profile retrieval, a method for retrieving a global ozone distribution from satellite Machines are selected to replace the forward model, which is the slowest part of ozone profile retrieval

  19. LUNAR SEISMIC PROFILING EXPERIMENT DESIGN VERIFICATION THERMAL PAGI OF

    E-Print Network [OSTI]

    Rathbun, Julie A.

    ATM 1109 LUNAR SEISMIC PROFILING EXPERIMENT DESIGN VERIFICATION THERMAL PAGI OF VACUUM TEST DATE 9 SEISMIC PROFILING EXPERIMENT DESIGN VERIFICATION THERMAL VACUUM TEST LIST OF TABLES AND FIGURES;Figure 4.9 5. 1 5.2 5.3-5.4 5.5 5.6 5.7-5.8 LUNAR SEISMIC PROFILING EXPERIMENT DESIGN VERIFICATION

  20. Mathematical models for the geographic profiling Mike O'Leary

    E-Print Network [OSTI]

    O'Leary, Michael

    Mathematical models for the geographic profiling problem Mike O'Leary Department of Mathematics Towson University Center for Evidence-Based Crime Policy George Mason University March 18, 2009 Mike O'Leary Department Mike O'Leary (Towson University) Geographic Profiling CEBCP 2 / 57 #12;The Geographic Profiling

  1. Tracking Elevated Pollution Layers with a Newly Developed Hyperspectral Sun/Sky Spectrometer (4STAR): Results from the TCAP 2012 and 2013 Campaigns

    SciTech Connect (OSTI)

    Segal Rozenhaimer, Michal; Russell, P. B.; Schmid, Beat; Redemann, Jens; Livingston, J. M.; Flynn, Connor J.; Johnson, Roy R.; Dunagan, Stephen; Shinozuka, Yohei; Herman, J. R.; Cede, A.; Abuhassan, N.; Comstock, Jennifer M.; Hubbe, John M.; Zelenyuk, Alla; Wilson, Jacqueline M.

    2014-03-16

    Total columnar amounts of water vapor, nitrogen dioxide (NO2) and ozone (O3) are derived from a newly developed, hyperspectral airborne sun-sky spectrometer (4STAR) for the first time during the two intensive phases of the Two Column Aerosol Project (TCAP) in summer 2012 and winter 2013 aboard the DOE G-1 aircraft. We compare results with coincident measurements. We find 0.045 g/cm2 (4.2%) negative bias and 0.28 g/cm2 (26.3%) root-mean-square (RMS) difference in water vapor layer comparison with in-situ hygrometer, and an overall RMS difference of 1.28 g/m3 (38%) water vapor amount in profile by profile comparisons, with differences distributed evenly around zero in most cases. The RMS differences for O3 values average to 3%, with a 1% negative bias for 4STAR compared with the spaceborne Ozone Measuring Instrument (OMI) along the aircraft flight-track for 14 flights during both TCAP phases. Ground-based comparisons with the Pandora spectrometer system at the Goddard Space Flight Center (GSFC), Greenbelt, Maryland showed excellent agreement between the instruments for both O3 and NO2, further emphasizing 4STAR’s new capabilities. During the summer phase, we have succeeded in identifying variations in elevated pollution layers corresponding to urban pollution outflow and transported biomass burning. This was done using clustering analysis of the retrieved products (e.g. Ångstrom exponent, NO2 and columnar water vapor), and was confirmed by aerosol type identification by HSRL2 aboard the NASA B-200 aircraft. These newly demonstrated 4STAR capabilities are expected to be instrumental in improving our understanding of atmospheric composition variability and aerosol-trace-gas interactions; they open new horizons and opportunities in airborne sunphotometry.

  2. Microsoft Word - NNSS Profile Instructions- Rev 0 02-27-12-Final...

    National Nuclear Security Administration (NNSA)

    of approval status will be provided. Approved profiles shall be reevaluated by the generator annually, and the profile amended as needed. Profiles must be changed if the...

  3. Impact of elevated CO2 on a Florida Scrub-oak Ecosystems

    SciTech Connect (OSTI)

    Drake, Bert G

    2013-01-01

    Since May of 1996, we have conducted an experiment in Florida Scrub Oak to determine the impact of elevated atmospheric CO2 and climate change on carbon, water, and nutrient cycling in this important terrestrial ecosystem. Florida scrub oak is the name for a collective of species occupying much of the Florida peninsula. The dominant tree species are oaks and the dwarf structure of this community makes it an excellent system in which to test hypotheses regarding the potential capacity of woody ecosystems to assimilate and sequester anthropogenic carbon. Scrub oak is fire dependent with a return cycle of 10-15 years, a time which would permit an experiment to follow the entire cycle. Our site is located on Cape Canaveral at the Kennedy Space Center, Florida. After burning in 1995, we built 16 open top chambers, half of which have been fumigated with pure CO2 sufficient to raise the concentration around the plants to 350 ppm above ambient. In the intervening 10 years we have non destructively measured biomass of shoots and roots, ecosystem gas exchange using chambers and eddy flux, leaf photosynthesis and respiration, soil respiration, and relevant environmental factors such as soil water availability, temperature, light, etc. The overwhelming result from analysis of our extensive data base is that elevated CO2 has had a profound impact on this ecosystem that, overall, has resulted in increased carbon accumulation in plant shoots, roots and litter. Our measurements of net ecosystem gas exchange also indicate that the ecosystem has accumulated carbon much in excess of the increased biomass or soil carbon suggesting a substantial export of carbon through the porous, sandy soil into the water table several meters below the surface. A major discovery is the powerful interaction between the stimulation of growth, photosynthesis, and respiration by elevated CO2 and other environmental factors particularly precipitation and nitrogen. Our measurements focused attention on: stimulation of ecosystem gas exchange by elevated atmospheric CO2; the architecture and distribution of coarse roots using the novel approach of ground penetrating radar; mechanisms for the disturbance of soil carbon pools via the "priming" effect; and how interannual and seasonal variation in precipitation alters the physiological response of key species to elevated CO2. This project was a collaboration between research groups at the Smithsonian Institution, NASA, the Dynamac Corporation, Northern Arizona University, and Old Dominion University in Norfolk, Virginia.

  4. Simulation of in-core neutron noise measurements for axial void profile reconstruction in boiling water reactors

    SciTech Connect (OSTI)

    Dykin, V.; Pazsit, I.

    2012-07-01

    A possibility to reconstruct the axial void profile from the simulated in-core neutron noise which is caused by density fluctuations in a Boiling Water Reactor (BWR) heated channel is considered. For this purpose, a self-contained model of the two-phase flow regime is constructed which has quantitatively and qualitatively similar properties to those observed in real BWRs. The model is subsequently used to simulate the signals of neutron detectors induced by the corresponding perturbations in the flow density. The bubbles are generated randomly in both space and time using Monte-Carlo techniques. The axial distribution of the bubble production is chosen such that the mean axial void fraction and void velocity follow the actual values of BWRs. The induced neutron noise signals are calculated and then processed by the standard signal analysis methods such as Auto-Power Spectral Density (APSD) and Cross-Power Spectral Density (CPSD). Two methods for axial void and velocity profiles reconstruction are discussed: the first one is based on the change of the break frequency of the neutron auto-power spectrum with axial core elevation, while the second refers to the estimation of transit times of propagating steam fluctuations between different axial detector positions. This paper summarizes the principles of the model and presents a numerical testing of the qualitative applicability to estimate the required parameters for the reconstruction of the void fraction profile from the neutron noise measurements. (authors)

  5. Characterization of X-ray generator beam profiles.

    SciTech Connect (OSTI)

    Mitchell, Dean J; Harding, Lee T.; Thoreson, Gregory G.; Theisen, Lisa Anne; Parmeter, John Ethan; Thompson, Kyle Richard

    2013-07-01

    T to compute the radiography properties of various materials, the flux profiles of X-ray sources must be characterized. This report describes the characterization of X-ray beam profiles from a Kimtron industrial 450 kVp radiography system with a Comet MXC-45 HP/11 bipolar oil-cooled X-ray tube. The empirical method described here uses a detector response function to derive photon flux profiles based on data collected with a small cadmium telluride detector. The flux profiles are then reduced to a simple parametric form that enables computation of beam profiles for arbitrary accelerator energies.

  6. The density profiles of hot galactic halo gas

    E-Print Network [OSTI]

    Steen H. Hansen; Jesper Sommer-Larsen

    2006-06-13

    Extended gas haloes around galaxies are a ubiquitous prediction of galaxy formation scenarios. However, the density profiles of this hot halo gas is virtually unknown, although various profiles have been suggested on theoretical grounds. In order to quantitatively address the gas profile, we compare galaxies from direct cosmological simulations with analytical solutions of the underlying gas equations. We find remarkable agreement between simulations and theoretical predictions. We present an expression for this gas profile with a non-trivial dependence on the total mass profile. This expression is useful when setting up equilibrium galaxy models for numerical experiments.

  7. Approach to Recover Hydrocarbons from Currently Off-Limit Areas of the Antrim Formation, MI Using Low-Impact Technologies

    SciTech Connect (OSTI)

    James Wood; William Quinlan

    2008-09-30

    The goal of this project was to develop and execute a novel drilling and completion program in the Antrim Shale near the western shoreline of Northern Michigan. The target was the gas in the Lower Antrim Formation (Upper Devonian). Another goal was to see if drilling permits could be obtained from the Michigan DNR that would allow exploitation of reserves currently off-limits to exploration. This project met both of these goals: the DNR (Michigan Department of Natural Resources) issued permits that allow drilling the shallow subsurface for exploration and production. This project obtained drilling permits for the original demonstration well AG-A-MING 4-12 HD (API: 21-009-58153-0000) and AG-A-MING 4-12 HD1 (API: 21-009-58153-0100) as well as for similar Antrim wells in Benzie County, MI, the Colfax 3-28 HD and nearby Colfax 2-28 HD which were substituted for the AG-A-MING well. This project also developed successful techniques and strategies for producing the shallow gas. In addition to the project demonstration well over 20 wells have been drilled to date into the shallow Antrim as a result of this project's findings. Further, fracture stimulation has proven to be a vital step in improving the deliverability of wells to deem them commercial. Our initial plan was very simple; the 'J-well' design. We proposed to drill a vertical or slant well 30.48 meters (100 feet) below the glacial drift, set required casing, then angle back up to tap the resource lying between the base to the drift and the conventional vertical well. The 'J'-well design was tested at Mancelona Township in Antrim County in February of 2007 with the St. Mancelona 2-12 HD 3.

  8. ?Linear Gas Jet with Tailored Density Profile"

    SciTech Connect (OSTI)

    KRISHNAN, Mahadevan

    2012-12-10

    Supersonic, highly collimated gas jets and gas-filled capillary discharge waveguides are two primary targets of choice for Laser Plasma Accelerators (LPA) . Present gas jets have lengths of only 2-4 mm at densities of 1-4E19 cm-3, sufficient for self trapping and electron acceleration to energies up to ~150 MeV. Capillary structures 3 cm long have been used to accelerate beams up to 1 GeV. Capillary discharges used in LPAs serve to guide the pump laser and optimize the energy gain. A wall-stabilized capillary discharge provides a transverse profile across the channel that helps guide the laser and combat diffraction. Gas injection via a fast nozzle at one end provides some longitudinal density control, to improve the coupling. Gas jets with uniform or controlled density profiles may be used to control electron bunch injection and are being integrated into capillary experiments to add tuning of density. The gas jet for electron injection has not yet been optimized. Our Ph-I results have provided the LPA community with an alternative path to realizing a 2-3GeV electron bunch using just a gas jet. For example, our slit/blade combination gives a 15-20mm long acceleration path with tunable density profile, serving as an alternative to a 20-mm long capillary discharge with gas injection at one end. In Ph-II, we will extend these results to longer nozzles, to see whether we can synthesize 30 or 40-mm long plasma channels for LPAs.

  9. Vertical Seismic Profiling | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page| Open Energy Information Serbia-EnhancingEt Al.,Turin, NewArkansas:Standards Jump to:VernonWisconsin:LabsOpenProfiling

  10. Performance profiles of major energy producers 1989

    SciTech Connect (OSTI)

    Not Available

    1991-01-23

    Performance Profiles of Major Energy Producers 1989 is the thirteenth annual report of the Energy Information Administration's (EIA) Financial Reporting System (FRS). The report examines financial and operating developments, with particular reference to the 23 major energy companies (the FRS companies'') required to report annually on Form EIA-28. Financial information is reported by major lines of business including oil and gas production, petroleum refining and marketing, and other energy operations. Domestic and international operations are examined separately in this report. It also traces key developments affecting the financial performance of major energy companies in 1989, as well as review of important trends.

  11. Performance profiles of major energy producers 1994

    SciTech Connect (OSTI)

    1996-02-01

    Performance Profiles of Major Energy Producers 1994 is the eighteenth annual report of the Energy Information Administration`s (EIA) Financial Reporting System (FRS). The report examines financial and operating developments in energy markets, with particular reference to the 24 major U.S. energy companies required to report annually on Form EIA-28. Financial information is reported by major lines of business, including oil and gas production, petroleum refining and marketing, other energy operations, and nonenergy businesses. Financial and operating results are presented in the context of energy market developments with a view toward identifying changing corporate strategies and measuring the performance of ongoing operations both in the United States and abroad.

  12. Project Cost Profile Spreadsheet | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustmentsShirleyEnergy AEnergyPresidential PermitDAYSDepartmentWork Progresses1,Project Cost Profile

  13. Debugging & Profiling | Argonne Leadership Computing Facility

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room NewsInformation Current HAB Packet HanfordDOEDanielDe novo Design of Debugging & Profiling

  14. Electromagnetic Profiling Techniques | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION J APPENDIX ECoopButtePowerEdisto Electric Coop, Inc Jump to:ElectraLinkofProfiling Techniques Jump

  15. Thermal Profiling of Residential Energy Use

    SciTech Connect (OSTI)

    Albert, A; Rajagopal, R

    2015-03-01

    This work describes a methodology for informing targeted demand-response (DR) and marketing programs that focus on the temperature-sensitive part of residential electricity demand. Our methodology uses data that is becoming readily available at utility companies-hourly energy consumption readings collected from "smart" electricity meters, as well as hourly temperature readings. To decompose individual consumption into a thermal-sensitive part and a base load (non-thermally-sensitive), we propose a model of temperature response that is based on thermal regimes, i.e., unobserved decisions of consumers to use their heating or cooling appliances. We use this model to extract useful benchmarks that compose thermal profiles of individual users, i.e., terse characterizations of the statistics of these users' temperature-sensitive consumption. We present example profiles generated using our model on real consumers, and show its performance on a large sample of residential users. This knowledge may, in turn, inform the DR program by allowing scarce operational and marketing budgets to be spent on the right users-those whose influencing will yield highest energy reductions-at the right time. We show that such segmentation and targeting of users may offer savings exceeding 100% of a random strategy.

  16. Reply to comment by K. M. Lau and K. M. Kim on "`Elevated heat pump' hypothesis for the aerosolmonsoon hydroclimate link

    E-Print Network [OSTI]

    Nigam, Sumant

    Reply to comment by K. M. Lau and K. M. Kim on "`Elevated heat pump' hypothesis for the aerosol. Bollasina (2011), Reply to comment by K. M. Lau and K. M. Kim on "`Elevated heat pump' hypothesis.1029/2010JD015246. [1] Lau and Kim's [2011] (hereinafter LK11) defense of the elevated heat pump (EHP

  17. Photosynthesis, carboxylation and leaf nitrogen responses of 16 species to elevated pCO2 across four free-air CO2

    E-Print Network [OSTI]

    Thomas, David D.

    Photosynthesis, carboxylation and leaf nitrogen responses of 16 species to elevated pCO2 across four free-air CO2 enrichment experiments in forest, grassland and desert D AV I D S . E L L S W O R T H species under long-term elevated CO2 exposure (elevated pCa) directly impacts ecosystem CO2 assimilation

  18. Note: A method for minimizing oxide formation during elevated temperature nanoindentation

    SciTech Connect (OSTI)

    Cheng, I. C.; Hodge, A. M., E-mail: ahodge@usc.edu [Department of Aerospace and Mechanical Engineering, University of Southern California, 3650 McClintock Avenue OHE430, Los Angeles, California 90089 (United States); Garcia-Sanchez, E. [Department of Aerospace and Mechanical Engineering, University of Southern California, 3650 McClintock Avenue OHE430, Los Angeles, California 90089 (United States); Facultad de Ingeniería Mecánica y Eléctrica, Universidad Autónoma de Nuevo León, Av. Universidad S/N, San Nicolás de los Garza, NL 66450 (Mexico)

    2014-09-15

    A standardized method to protect metallic samples and minimize oxide formation during elevated-temperature nanoindentation was adapted to a commercial instrument. Nanoindentation was performed on Al (100), Cu (100), and W (100) single crystals submerged in vacuum oil at 200 °C, while the surface morphology and oxidation was carefully monitored using atomic force microscopy (AFM) and X-ray photoelectron spectroscopy (XPS). The results were compared to room temperature and 200 °C nanoindentation tests performed without oil, in order to evaluate the feasibility of using the oil as a protective medium. Extensive surface characterization demonstrated that this methodology is effective for nanoscale testing.

  19. Synthesis of Scrub-Oak Ecosystem Responses to Elevated CO2

    SciTech Connect (OSTI)

    Hungate, Bruce

    2014-11-07

    This report summarizes a synthesis project of a long-term global change experiment conducted at the Kennedy Space Center, Florida, investigating how increasing concentrations of atmospheric carbon dioxide (CO2) influences the functioning of a fire-dominated scrub-oak ecosystem. The experiment began in 1996 and ended in 2007. Results presented here summarize the effects of elevated CO2 on plant growth, soil processes, carbon and nutrient cycling, and other responses. Products include archived data from the experiment, as well as six publications in the peer-reviewed literature.

  20. Arsenite evokes IL-6 secretion, autocrine regulation of STAT3 signaling, and miR-21 expression, processes involved in the EMT and malignant transformation of human bronchial epithelial cells

    SciTech Connect (OSTI)

    Luo, Fei; Xu, Yuan; Ling, Min; Zhao, Yue; Xu, Wenchao; Liang, Xiao; Jiang, Rongrong; Wang, Bairu; Bian, Qian; Liu, Qizhan

    2013-11-15

    Arsenite is an established human carcinogen, and arsenite-induced inflammation contributes to malignant transformation of cells, but the molecular mechanisms by which cancers are produced remain to be established. The present results showed that, evoked by arsenite, secretion of interleukin-6 (IL-6), a pro-inflammatory cytokine, led to the activation of STAT3, a transcription activator, and to increased levels of a microRNA, miR-21. Blocking IL-6 with anti-IL-6 antibody and inhibiting STAT3 activation reduced miR-21 expression. For human bronchial epithelial cells, cultured in the presence of anti-IL-6 antibody for 3 days, the arsenite-induced EMT and malignant transformation were reversed. Thus, IL-6, acting on STAT3 signaling, which up-regulates miR-21in an autocrine manner, contributes to the EMT induced by arsenite. These data define a link from inflammation to EMT in the arsenite-induced malignant transformation of HBE cells. This link, mediated through miRNAs, establishes a mechanism for arsenite-induced lung carcinogenesis. - Highlights: • Arsenite evokes IL-6 secretion. • IL-6 autocrine mediates STAT3 signaling and up-regulates miR-21expression. • Inflammation is involved in arsenite-induced EMT.

  1. Elevated-Temperature Ferritic and Martensitic Steels and Their Application to Future Nuclear Reactors

    SciTech Connect (OSTI)

    Klueh, RL

    2005-01-31

    In the 1970s, high-chromium (9-12% Cr) ferritic/martensitic steels became candidates for elevated-temperature applications in the core of fast reactors. Steels developed for conventional power plants, such as Sandvik HT9, a nominally Fe-12Cr-1Mo-0.5W-0.5Ni-0.25V-0.2C steel (composition in wt %), were considered in the United States, Europe, and Japan. Now, a new generation of fission reactors is in the planning stage, and ferritic, bainitic, and martensitic steels are again candidates for in-core and out-of-core applications. Since the 1970s, advances have been made in developing steels with 2-12% Cr for conventional power plants that are significant improvements over steels originally considered. This paper will review the development of the new steels to illustrate the advantages they offer for the new reactor concepts. Elevated-temperature mechanical properties will be emphasized. Effects of alloying additions on long-time thermal exposure with and without stress (creep) will be examined. Information on neutron radiation effects will be discussed as it applies to ferritic and martensitic steels.

  2. Elevated temperature load-order effects on austenitic steel life predictions

    SciTech Connect (OSTI)

    Weiner, E.O.

    1989-03-01

    The design of nuclear pressure vessel components may typically involve a few hundred or more cyclic thermal loadings of various levels coupled with steady mechanical loads. Ordering of these loading events may not be detailed in the design specification. Thermal loading usually implies plastic deformation, and elevated temperature design must consider creep deformation and damage. Plastic creep solutions are history dependent. Even if some ordering is given in a design specification, practical cost considerations of inelastic analysis may impose a need to group transients. The analyst is frequently faced with the task of showing that his choice of load sequence in an elevated temperature design analysis is a conservative one. In facing such a task, the inelastic strain accumulation and creep-fatigue interaction criteria of the ASME N-47 (ASME 1986) Code Case usually govern. An effort associated with the Fast Flux Test Facility was to study the effects of load ordering the light of these criteria. The effects of a seismic disturbance were included. An additional interest was the effect of the alpha reset hardening modification (Corum, 1987), which prevents undue drift of the yield surface. An effect of reverse plasticity on subsequent creep, the beta effect, was also used. About two hundred inelastic analyses of a thin cylinder were carried out. The scope of work reported in this paper includes a study by J. Phillips (Phillips, 1982), extended with damage calculations. 4 refs., 9 figs., 2 tabs.

  3. Elevated expression of ERK 2 in human tumor cells chronically treated with PD98059

    SciTech Connect (OSTI)

    Kanda, Shigeru [Department of Molecular Microbiology and Immunology, Division of Endothelial Cell Biology, Nagasaki University Graduate School of Biomedical Science, Nagasaki (Japan)]. E-mail: skanda-jua@umin.net; Kanetake, Hiroshi [Department of Urology, Nagasaki University Graduate School of Biomedical Science, Nagasaki (Japan); Miyata, Yasuyoshi [Department of Urology, Nagasaki University Graduate School of Biomedical Science, Nagasaki (Japan)

    2006-07-14

    We examined the effect of chronic exposure of tumor cells to a mitogen-activated protein kinase/extracellular signal-regulated kinases (ERK) kinase inhibitor, PD98059, on cell proliferation was investigated. Human renal carcinoma cells (ACHN) and prostatic carcinoma cells (DU145) were cultured in the presence of PD98059 for more than 4 weeks (denoted ACHN (PD) cells and DU145 (PD) cells, respectively) and proliferation and signal transduction pathways were examined. PD98059 significantly inhibited the proliferation of parental cells. However, PD98059 failed to inhibit proliferation of ACHN (PD) and DU145 (PD) cells significantly. Expression of ERK 1 and 2 was elevated in these cells. These phenotypes were reversible. Downregulation of ERK 2, but not ERK 1, by small interfering RNA significantly inhibited the proliferation of ACHN (PD) and DU145 (PD) cells. Taken together, chronic exposure of tumor cells to PD98059 induced elevated expression of ERK 2, which was associated with decreased sensitivity of cellular proliferation to PD98059.

  4. Effects of elevated CO{sub 2} on Chesapeake Bay wetlands. [Progress report, 1988--1989

    SciTech Connect (OSTI)

    Drake, B.G.; Arp, W.J.; Balduman, L.

    1990-12-31

    Research during 1988--89 focused on several new aspects of the response of the salt marsh ecosystem to elevated CO{sub 2}. In previous years we gave highest priority to studies of the effect of CO{sub 2} on biomass production into above and below-ground tissues, nitrogen content, light response of photosynthesis of single leaves, leaf water potential and carbon dioxide and water vapor exchange between the plant canopy and the ambient air. Result from the work in 87 and 88 had shown that the C3 plant, Scirpus olneyi, responded vigorously to elevated CO{sub 2} but the two C4 species, Spartina patens and Distichlis spicata did not. The responses of photosynthesis were also reflected in the canopy and ecosystem processes. Thus our emphasis shifted from determining the growth responses to exploring photosynthesis in greater detail. The main questions were: does acclimation to high CO{sub 2} involve reduction of some aspect of photosynthesis either at the single leaf level or in canopy structure? How much more carbon will be accumulated in a high CO{sub 2} than under present CO{sub 2} concentration? Our results give us partial answers to these questions but since the long term aspect of CO{sub 2} stimulation remains the most important one, it is unlikely that we can do more than add some pieces of data to a continuing debate in the ecological community regarding the eventual effect of CO{sub 2} on ecosystems.

  5. Performance profiles of major energy producers 1992

    SciTech Connect (OSTI)

    Not Available

    1994-01-13

    Performance Profiles of Major Energy Producers 1992 is the sixteenth annual report of the Energy Information Administration`s (EIA) Financial Reporting System (FRS). The report examines financial and operating developments, with particular reference to the 25 major energy companies (the FRS companies) required to report annually on Form EIA-28. Financial information is reported by major lines of business, including oil and gas production, petroleum refining and marketing, and other energy operations. Domestic and international operations are examined separately in this report. The data are presented in the context of key energy market developments with a view toward identifying changing strategies of corporate development and measuring the apparent success of current ongoing operations.

  6. An introduction to the concept of profiles

    SciTech Connect (OSTI)

    Fogel, G.; Doll, D.

    1997-09-01

    There has been limited general acceptance of lubricant analysis as a predictive maintenance tool in industry as compared to say vibration monitoring. There is perhaps a perception within industry that Lubricant analysis has failed to deliver on some of the promises that it has made. However, when one looks at so called benchmark programs that exhibit the practices of industry leaders, and measures the achievements of such programs there is no doubt that if applied correctly that lubricant analysis is an invaluable tool in the development of an advanced approach to maintenance. There are many issues which create a successful lubricant analysis program, one of which is the appropriate use of existing technologies to ensure optimum value in the implementation of a program. This paper introduces the concept of Profiles as a framework for the effective utilization of the correct lubricant analysis technologies.

  7. Performance profiles of major energy producers 1993

    SciTech Connect (OSTI)

    1995-01-01

    Performance Profiles of Major Energy Producers 1993 is the seventeenth annual report of the Energy Information Administration`s (EIA) Financial Reporting System (FRS). The report examines financial and operating developments in energy markets, with particular reference to the 25 major US energy companies required to report annually on Form EIA-28. Financial information is reported by major liens of business, including oil and gas production, petroleum refining and marketing, other energy operations, and nonenergy businesses. Financial and operating results are presented in the context of energy market developments with a view toward identifying changing corporate strategies and measuring the performance of ongoing operations both in the US and abroad. This year`s report analyzes financial and operating developments for 1993 (Part 1: Developments in 1993) and also reviews key developments during the 20 years following the Arab Oil Embargo of 1973--1974 (Part 2: Major Energy Company Strategies Since the Arab Oil Embargo). 49 figs., 104 tabs.

  8. Gene expression profiles in irradiated cancer cells

    SciTech Connect (OSTI)

    Minafra, L.; Bravatà, V.; Russo, G.; Ripamonti, M.; Gilardi, M. C.

    2013-07-26

    Knowledge of the molecular and genetic mechanisms underlying cellular response to radiation may provide new avenues to develop innovative predictive tests of radiosensitivity of tumours and normal tissues and to improve individual therapy. Nowadays very few studies describe molecular changes induced by hadrontherapy treatments, therefore this field has to be explored and clarified. High-throughput methodologies, such as DNA microarray, allow us to analyse mRNA expression of thousands of genes simultaneously in order to discover new genes and pathways as targets of response to hadrontherapy. Our aim is to elucidate the molecular networks involved in the sensitivity/resistance of cancer cell lines subjected to hadrontherapy treatments with a genomewide approach by using cDNA microarray technology to identify gene expression profiles and candidate genes responsible of differential cellular responses.

  9. Adaptive method for electron bunch profile prediction

    SciTech Connect (OSTI)

    Scheinker, Alexander; Gessner, Spencer

    2015-10-15

    We report on an experiment performed at the Facility for Advanced Accelerator Experimental Tests (FACET) at SLAC National Accelerator Laboratory, in which a new adaptive control algorithm, one with known, bounded update rates, despite operating on analytically unknown cost functions, was utilized in order to provide quasi-real-time bunch property estimates of the electron beam. Multiple parameters, such as arbitrary rf phase settings and other time-varying accelerator properties, were simultaneously tuned in order to match a simulated bunch energy spectrum with a measured energy spectrum. The simple adaptive scheme was digitally implemented using matlab and the experimental physics and industrial control system. Thus, the main result is a nonintrusive, nondestructive, real-time diagnostic scheme for prediction of bunch profiles, as well as other beam parameters, the precise control of which are important for the plasma wakefield acceleration experiments being explored at FACET.

  10. ITP Petroleum Refining: Profile of the Petroleum Refining Industry...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    (November 2007) ITP Petroleum Refining: Energy Efficiency Roadmap for Petroleum Refineries in California ITP Petroleum Refining: Profile of the Petroleum Refining Industry in...

  11. ITP Petroleum Refining: Energy and Environmental Profile of the...

    Energy Savers [EERE]

    Profile of the U.S. Petroleum Refining Industry (November 2007) Bandwidth Study U.S. Petroleum Refining ITP Petroleum Refining: Technology Roadmap for the Petroleum Industry...

  12. Project Profile: CSP Energy Storage Solutions - Multiple Technologies...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Project Profile: CSP Energy Storage Solutions - Multiple Technologies Compared US Solar Holdings logo US Solar Holdings, under the Thermal Storage FOA, is aiming to...

  13. Project Profile: Novel Thermal Energy Storage Systems for Concentratin...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Storage Systems for Concentrating Solar Power Project Profile: Novel Thermal Energy Storage Systems for Concentrating Solar Power University of Connecticut logo The...

  14. Project Profile: Fundamental Corrosion Studies in High-Temperature...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Fundamental Corrosion Studies in High-Temperature Molten Salt Systems for Next-Generation CSP Systems Project Profile: Fundamental Corrosion Studies in High-Temperature Molten Salt...

  15. Project Profile: Modular and Scalable Baseload Molten Salt Plant...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Modular and Scalable Baseload Molten Salt Plant Conceptual Design and Feasibility Project Profile: Modular and Scalable Baseload Molten Salt Plant Conceptual Design and Feasibility...

  16. Project Profile: Cleanable and Hardcoat Coatings for Increased...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Cleanable and Hardcoat Coatings for Increased Durability of Silvered Polymeric Mirrors Project Profile: Cleanable and Hardcoat Coatings for Increased Durability of Silvered...

  17. Project Profile: Reducing the Cost of Thermal Energy Storage...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Reducing the Cost of Thermal Energy Storage for Parabolic Trough Solar Power Plants Project Profile: Reducing the Cost of Thermal Energy Storage for Parabolic Trough Solar Power...

  18. Project Profile: Innovative Phase Change Thermal Energy Storage...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Phase Change Thermal Energy Storage Solution for Baseload Power Project Profile: Innovative Phase Change Thermal Energy Storage Solution for Baseload Power Infinia logo Infinia,...

  19. Project Profile: Brayton Solar Power Conversion System | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Solar Power Conversion System Project Profile: Brayton Solar Power Conversion System Brayton Energy logo Brayton Energy, under the CSP R&D FOA, is looking to demonstrate the...

  20. State Energy Risk Assessment Initiative - State Energy Risk Profiles...

    Energy Savers [EERE]

    Mission Energy Infrastructure Modeling and Analysis State Energy Risk Assessment Initiative - State Energy Risk Profiles State Energy Risk Assessment Initiative - State...

  1. Building America Top Innovations Hall of Fame Profile - Building...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Building America Top Innovations Hall of Fame Profile - Building America's Top Innovations Propel the Home Building Industry toward Higher Performance Building America Top...

  2. Building America Top Innovations Hall of Fame Profile ? Integration...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    are essential to realizing the promise of high-performance homes. BUILDING AMERICA TOP INNOVATIONS HALL OF FAME PROFILE INNOVATIONS CATEGORY: 1. Advanced Technologies and...

  3. PROJECT PROFILE: California Center for Sustainable Energy (Solar...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    California Center for Sustainable Energy (Solar Market Pathways) PROJECT PROFILE: California Center for Sustainable Energy (Solar Market Pathways) Title: Virtual Net Metering...

  4. Project Profile: Sensible Heat, Direct, Dual-Media Thermal Energy...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Sensible Heat, Direct, Dual-Media Thermal Energy Storage Module Project Profile: Sensible Heat, Direct, Dual-Media Thermal Energy Storage Module Acciona logo Acciona Solar, under...

  5. Evaluation of Thermal Evolution Profiles and Estimation of Kinetic...

    Office of Scientific and Technical Information (OSTI)

    Evaluation of Thermal Evolution Profiles and Estimation of Kinetic Parameters for Pyrolysis of CoalCorn Stover Blends Using Thermogravimetric Analysis Citation Details...

  6. Building America Top Innovations Hall of Fame Profile - Building...

    Energy Savers [EERE]

    Top Innovations Hall of Fame Profile - Building America's Top Innovations Propel the Home Building Industry toward Higher Performance Building America Top Innovations Hall of Fame...

  7. Project Profile: Development and Performance Evaluation of High...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Evaluation of High Temperature Concrete for Thermal Energy Storage for Solar Power Generation Project Profile: Development and Performance Evaluation of High Temperature Concrete...

  8. Project Profile: Novel Thermal Storage Technologies for Concentrating...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Storage Technologies for Concentrating Solar Power Generation Project Profile: Novel Thermal Storage Technologies for Concentrating Solar Power Generation Lehigh logo Lehigh...

  9. Profiles in Leadership: David Mohler, Deputy Assistant Secretary...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    David Mohler, Deputy Assistant Secretary for Clean Coal and Carbon Management Profiles in Leadership: David Mohler, Deputy Assistant Secretary for Clean Coal and Carbon Management...

  10. Pharmacologic Profile of the Adnectin BMS-962476, a Small Protein...

    Office of Scientific and Technical Information (OSTI)

    Pharmacologic Profile of the Adnectin BMS-962476, a Small Protein Biologic Alternative to PCSK9 Antibodies for Low-Density Lipoprotein Lowering Citation Details In-Document Search...

  11. Project Profile: High-Temperature Solar Selective Coating Development...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Solar Selective Coating Development for Power Tower Receivers Project Profile: High-Temperature Solar Selective Coating Development for Power Tower Receivers Sandia National...

  12. Vertical Seismic Profiling At Neal Hot Springs Geothermal Area...

    Open Energy Info (EERE)

    Vertical Seismic Profiling At Neal Hot Springs Geothermal Area (Colorado School of Mines and Imperial College London, 2011) Jump to: navigation, search GEOTHERMAL ENERGYGeothermal...

  13. Lithologic Descriptions and Temperature Profiles of Five Wells...

    Open Energy Info (EERE)

    Wells in the Southwestern Valles Caldera Region, New Mexico Abstract The subsurface stratigraphy and temperature profiles of the southern and western Valles caldera region have...

  14. Project Profile: Hybrid Organic Silicone HTF Utilizing Endothermic...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Hybrid Organic Silicone HTF Utilizing Endothermic Chemical Reactions for Latent Heat Storage Project Profile: Hybrid Organic Silicone HTF Utilizing Endothermic Chemical Reactions...

  15. The PIKfyve–ArPIKfyve–Sac3 triad in human breast cancer: Functional link between elevated Sac3 phosphatase and enhanced proliferation of triple negative cell lines

    SciTech Connect (OSTI)

    Ikonomov, Ognian C. Filios, Catherine Sbrissa, Diego Chen, Xuequn Shisheva, Assia

    2013-10-18

    Highlights: •We assess PAS complex proteins and phosphoinositide levels in breast cancer cells. •Sac3 and ArPIKfyve are markedly elevated in triple-negative breast cancer cells. •Sac3 silencing inhibits proliferation in triple-negative breast cancer cell lines. •Phosphoinositide profiles are altered in breast cancer cells. •This is the first evidence linking high Sac3 with breast cancer cell proliferation. -- Abstract: The phosphoinositide 5-kinase PIKfyve and 5-phosphatase Sac3 are scaffolded by ArPIKfyve in the PIKfyve–ArPIKfyve–Sac3 (PAS) regulatory complex to trigger a unique loop of PtdIns3P–PtdIns(3,5)P{sub 2} synthesis and turnover. Whereas the metabolizing enzymes of the other 3-phosphoinositides have already been implicated in breast cancer, the role of the PAS proteins and the PtdIns3P–PtdIns(3,5)P{sub 2} conversion is unknown. To begin elucidating their roles, in this study we monitored the endogenous levels of the PAS complex proteins in cell lines derived from hormone-receptor positive (MCF7 and T47D) or triple-negative breast cancers (TNBC) (BT20, BT549 and MDA-MB-231) as well as in MCF10A cells derived from non-tumorigenic mastectomy. We report profound upregulation of Sac3 and ArPIKfyve in the triple negative vs. hormone-sensitive breast cancer or non-tumorigenic cells, with BT cell lines showing the highest levels. siRNA-mediated knockdown of Sac3, but not that of PIKfyve, significantly inhibited proliferation of BT20 and BT549 cells. In these cells, knockdown of ArPIKfyve had only a minor effect, consistent with a primary role for Sac3 in TNBC cell proliferation. Intriguingly, steady-state levels of PtdIns(3,5)P{sub 2} in BT20 and T47D cells were similar despite the 6-fold difference in Sac3 levels between these cell lines. However, steady-state levels of PtdIns3P and PtdIns5P, both regulated by the PAS complex, were significantly reduced in BT20 vs. T47D or MCF10A cell lines, consistent with elevated Sac3 affecting directly or indirectly the homeostasis of these lipids in TNBC. Together, our results uncover an unexpected role for Sac3 phosphatase in TNBC cell proliferation. Database analyses, discussed herein, reinforce the involvement of Sac3 in breast cancer pathogenesis.

  16. Ecloud Build-Up Simulations for the FNAL MI for a Mixed Fill Pattern: Dependence on Peak SEY and Pulse Intensity During the Ramp

    SciTech Connect (OSTI)

    Furman, M. A.

    2010-12-11

    We present simulation results of the build-up of the electron-cloud density n{sub e} in three regions of the FNAL Main Injector (MI) for a beam fill pattern made up of 5 double booster batches followed by a 6th single batch. We vary the pulse intensity in the range N{sub t} = (2-5) x 10{sup 13}, and the beam kinetic energy in the range E{sub k} = 8-120 GeV. We assume a secondary electron emission model qualitatively corresponding to TiN, except that we let the peak value of the secondary electron yield (SEY) {delta}{sub max} vary as a free parameter in a fairly broad range. Our main conclusions are: (1) At fixed N{sub t} there is a clear threshold behavior of n{sub e} as a function of {delta}{sub max} in the range {approx} 1.1-1.3. (2) At fixed {delta}{sub max}, there is a threshold behavior of n{sub e} as a function of N{sub t} provided {delta}{sub max} is sufficiently high; the threshold value of N{sub t} is a function of the characteristics of the region being simulated. (3) The dependence on E{sub k} is weak except possibly at transition energy. Most of these results were informally presented to the relevant MI personnel in April 2010.

  17. Structural characteristics and elevated temperature mechanical properties of AJ62 Mg alloy

    SciTech Connect (OSTI)

    Kubásek, J., E-mail: Jiri.Kubasek@vscht.cz; Vojt?ch, D.; Martínek, M.

    2013-12-15

    Structure and mechanical properties of the novel casting AJ62 (Mg–6Al–2Sr) alloy developed for elevated temperature applications were studied. The AJ62 alloy was compared to commercial casting AZ91 (Mg–9Al–1Zn) and WE43 (Mg–4Y–3RE) alloys. The structure was examined by scanning electron microscopy, x-ray diffraction and energy dispersive spectrometry. Mechanical properties were characterized by Viskers hardness measurements in the as-cast state and after a long-term heat treatment at 250 °C/150 hours. Compressive mechanical tests were also carried out both at room and elevated temperatures. Compressive creep tests were conducted at a temperature of 250 °C and compressive stresses of 60, 100 and 140 MPa. The structure of the AJ62 alloy consisted of primary ?-Mg dendrites and interdendritic nework of the Al{sub 4}Sr and massive Al{sub 3}Mg{sub 13}Sr phases. By increasing the cooling rate during solidification from 10 and 120 K/s the average dendrite arm thickness decreased from 18 to 5 ?m and the total volume fraction of the interdendritic phases from 20% to 30%. Both factors slightly increased hardness and compressive strength. The room temperature compressive strength and hardness of the alloy solidified at 30 K/s were 298 MPa and 50 HV 5, i.e. similar to those of the as-cast WE43 alloy and lower than those of the AZ91 alloy. At 250 °C the compressive strength of the AJ62 alloy decreased by 50 MPa, whereas those of the AZ91 and WE43 alloys by 100 and 20 MPa, respectively. The creep rate of the AJ62 alloy was higher than that of the WE43 alloy, but significantly lower in comparison with the AZ91 alloy. Different thermal stabilities of the alloys were discussed and related to structural changes during elevated temperature expositions. - Highlights: • Small effect of cooling rate on the compressive strength and hardness of AJ 62 • A bit lower compressive strength of AJ 62 compared to AZ91 at room temperature • Higher resistance of the AJ 62 alloy to the creep process in compression compared to AZ91 • Excellent thermal stability and creep resistance of the alloy WE 43 • Improved thermal stability and creep resistance in order WE43 > AJ62 >> AZ91.

  18. Digital Elevation Model, 0.25 m, Barrow Environmental Observatory, Alaska, 2013

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Cathy Wilson; Garrett Altmann

    2015-11-20

    This 0.25m horizontal resolution digital elevation model, DEM, was developed from Airborne Laser Altimetry flown by Aerometric Inc, now known as Quantum Spatial, Inc. on 12 July, 2013. One Mission was flown and the data jointly processed with LANL personnel to produce a 0.25m DEM covering a region approximately 2.8km wide and 12.4km long extending from the coast above North Salt Lagoon to south of Gas Well Road. This DEM encompasses a diverse range of hydrologic, geomorphic, geophysical and biological features typical of the Barrow Peninsula. Vertical accuracy at the 95% confidence interval was computed as 0.143m. The coordinate system, datum, and geoid for this DEM are UTM Zone 4N, NAD83 (2011), NAVD88 (GEOID09).

  19. Gas diffusion electrode setup for catalyst testing in concentrated phosphoric acid at elevated temperatures

    SciTech Connect (OSTI)

    Wiberg, Gustav K. H. E-mail: m.arenz@chem.ku.dk; Fleige, Michael; Arenz, Matthias E-mail: m.arenz@chem.ku.dk

    2015-02-15

    We present a detailed description of the construction and testing of an electrochemical cell setup allowing the investigation of a gas diffusion electrode containing carbon supported high surface area catalysts. The setup is designed for measurements in concentrated phosphoric acid at elevated temperature, i.e., very close to the actual conditions in high temperature proton exchange membrane fuel cells (HT-PEMFCs). The cell consists of a stainless steel flow field and a PEEK plastic cell body comprising the electrochemical cell, which exhibits a three electrode configuration. The cell body and flow field are braced using a KF-25 vacuum flange clamp, which allows an easy assembly of the setup. As demonstrated, the setup can be used to investigate temperature dependent electrochemical processes on high surface area type electrocatalysts, but it also enables quick screening tests of HT-PEMFC catalysts under realistic conditions.

  20. Elevated Temperature Primary Load Design Method Using Pseudo Elastic-Perfectly Plastic Model

    SciTech Connect (OSTI)

    Carter, Peter [Stress Engineering Services Inc.] [Stress Engineering Services Inc.; Sham, Sam [ORNL] [ORNL; Jetter, Robert I [Consultant] [Consultant

    2012-01-01

    A new primary load design method for elevated temperature service has been developed. Codification of the procedure in an ASME Boiler and Pressure Vessel Code, Section III Code Case is being pursued. The proposed primary load design method is intended to provide the same margins on creep rupture, yielding and creep deformation for a component or structure that are implicit in the allowable stress data. It provides a methodology that does not require stress classification and is also applicable to a full range of temperature above and below the creep regime. Use of elastic-perfectly plastic analysis based on allowable stress with corrections for constraint, steady state stress and creep ductility is described. This approach is intended to ensure that traditional primary stresses are the basis for design, taking into account ductility limits to stress re-distribution and multiaxial rupture criteria.

  1. Temperature elevation by HIFU in ex vivo porcine muscle: MRI measurement and simulation study

    SciTech Connect (OSTI)

    Solovchuk, Maxim A., E-mail: solovchuk@gmail.com [Center for Advanced Study in Theoretical Sciences (CASTS), National Taiwan University, Taipei 10617, Taiwan (China); Hwang, San Chao; Chang, Hsu [Medical Engineering Research Division, National Health Research Institute, Miaoli 35053, Taiwan (China)] [Medical Engineering Research Division, National Health Research Institute, Miaoli 35053, Taiwan (China); Thiriet, Marc [Sorbonne Universités, UPMC Univ Paris 06, UMR 7598, Laboratoire Jacques-Louis Lions, F-75005, Paris (France)] [Sorbonne Universités, UPMC Univ Paris 06, UMR 7598, Laboratoire Jacques-Louis Lions, F-75005, Paris (France); Sheu, Tony W. H., E-mail: twhsheu@ntu.edu.tw [Department of Engineering Science and Ocean Engineering, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei 10617, Taiwan, Republic of China and Center for Advanced Study in Theoretical Sciences (CASTS), National Taiwan University, Taipei 10617, Taiwan (China)] [Department of Engineering Science and Ocean Engineering, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei 10617, Taiwan, Republic of China and Center for Advanced Study in Theoretical Sciences (CASTS), National Taiwan University, Taipei 10617, Taiwan (China)

    2014-05-15

    Purpose: High-intensity focused ultrasound is a rapidly developing medical technology with a large number of potential clinical applications. Computational model can play a pivotal role in the planning and optimization of the treatment based on the patient's image. Nonlinear propagation effects can significantly affect the temperature elevation and should be taken into account. In order to investigate the importance of nonlinear propagation effects, nonlinear Westervelt equation was solved. Weak nonlinear propagation effects were studied. The purpose of this study was to investigate the correlation between the predicted and measured temperature elevations and lesion in a porcine muscle. Methods: The investigated single-element transducer has a focal length of 12 cm, an aperture of 8 cm, and frequency of 1.08 MHz. Porcine muscle was heated for 30 s by focused ultrasound transducer with an acoustic power in the range of 24–56 W. The theoretical model consists of nonlinear Westervelt equation with relaxation effects being taken into account and Pennes bioheat equation. Results: Excellent agreement between the measured and simulated temperature rises was found. For peak temperatures above 85–90?°C “preboiling” or cavitation activity appears and lesion distortion starts, causing small discrepancy between the measured and simulated temperature rises. From the measurements and simulations, it was shown that distortion of the lesion was caused by the “preboiling” activity. Conclusions: The present study demonstrated that for peak temperatures below 85–90?°C numerical simulation results are in excellent agreement with the experimental data in three dimensions. Both temperature rise and lesion size can be well predicted. Due to nonlinear effect the temperature in the focal region can be increased compared with the linear case. The current magnetic resonance imaging (MRI) resolution is not sufficient. Due to the inevitable averaging the measured temperature can be 10–30?°C lower than the peak temperature. Computational fluid dynamics can provide additional important information that is lost using a state of the art MRI device.

  2. A SIMPLE APPROACH TO HIGH RESOLUTION SEISMIC PROFILING FOR COAL *

    E-Print Network [OSTI]

    A SIMPLE APPROACH TO HIGH RESOLUTION SEISMIC PROFILING FOR COAL * BY A. ZIOLKOWSKI ** and W. E Seismic Profiling for Coal, Geophysical Prospecting 27, 360-393, Seismic exploration techniques which have been developed for oil prospecting contrib- ute a valuable means for surveying coal measures. Since

  3. Transverse Diffusion of Laminar Flow Profiles To Produce Capillary Nanoreactors

    E-Print Network [OSTI]

    Krylov, Sergey

    Transverse Diffusion of Laminar Flow Profiles To Produce Capillary Nanoreactors Victor Okhonin, Xin We introduce transverse diffusion of laminar flow profiles (TDLFP), the first generic method the capillary by pressure as a series of consecutive plugs. Due to the laminar nature of flow inside

  4. Raman Lidar Profiles–Temperature (RLPROFTEMP) Value-Added Product

    SciTech Connect (OSTI)

    Newsom, RK; Sivaraman, C; McFarlane, SA

    2012-10-31

    The purpose of this document is to describe the Raman Lidar Profiles–Temperature (RLPROFTEMP) value-added product (VAP) and the procedures used to derive atmospheric temperature profiles from the raw RL measurements. Sections 2 and 4 describe the input and output variables, respectively. Section 3 discusses the theory behind the measurement and the details of the algorithm, including calibration and overlap correction.

  5. Ris-PhD-Report Sensing the wind profile

    E-Print Network [OSTI]

    Risø-PhD-Report Sensing the wind profile Alfredo Peña Risø-PhD-45(EN) March 2009 #12;Author: Alfredo Peña1,2 Title: Sensing the wind profile 1 Risø National Laboratory for Sustainable Energy, measure, and model the wind prole in and beyond the surface layer by combining observations from cup

  6. Mathematical models for the geographic profiling Mike O'Leary

    E-Print Network [OSTI]

    O'Leary, Michael

    Mathematical models for the geographic profiling problem Mike O'Leary Department of Mathematics Towson University UCLA Applied Mathematics Colloquium November 12, 2009 Mike O'Leary (Towson University Police Department Mike O'Leary (Towson University) Geographic Profiling November 12, 2009 2 / 70 #12;The

  7. The Mathematics of Geographic Profiling Mike O'Leary

    E-Print Network [OSTI]

    O'Leary, Michael

    The Mathematics of Geographic Profiling Mike O'Leary Department of Mathematics Towson University The NIJ Conference 2008 Mike O'Leary (Towson University) The Mathematics of Geographic Profiling The NIJ Erickson, Iara Infosino, and Tommy Sexton Phil Canter, Baltimore County Police Department Mike O'Leary

  8. Advances in Geographic Profiling Mike O'Leary

    E-Print Network [OSTI]

    O'Leary, Michael

    Advances in Geographic Profiling Mike O'Leary Department of Mathematics Towson University 31st Applied Geography Conference Wilmington, DE October 2008 Mike O'Leary (Towson University) Advances Department Mike O'Leary (Towson University) Advances in Geographic Profiling Applied Geography Conference 2

  9. Mathematical models for the geographic profiling Mike O'Leary

    E-Print Network [OSTI]

    O'Leary, Michael

    Mathematical models for the geographic profiling problem Mike O'Leary Department of Mathematics Towson University Georgetown University Mathematics Department Colloquium March 17, 2009 Mike O'Leary Phil Canter, Baltimore County Police Department Mike O'Leary (Towson University) Geographic Profiling

  10. Validation of operational ozone profiles from the Ozone Monitoring Instrument

    E-Print Network [OSTI]

    Validation of operational ozone profiles from the Ozone Monitoring Instrument M. Kroon,1 J. F. de we present the validation results of the operational vertical ozone profiles retrieved from the nadir observations by the Ozone Monitoring Instrument (OMI) aboard the NASA Earth Observing System (EOS) Aura

  11. www.VadoseZoneJournal.org Nonmonotone Satura on Profiles

    E-Print Network [OSTI]

    Zegeling, Paul

    saturation profiles during immiscible displacement. Despite its failure to predict residual saturations applica- tions such as reservoir engineering (see Lake, 1989) or groundwater hydrology (see Marsily, 1986 the shortcomings of the traditional theory for nonmono- tone traveling saturation profiles (so-called saturation

  12. Forecasting Hourly Electricity Load Profile Using Neural Networks

    E-Print Network [OSTI]

    Koprinska, Irena

    Forecasting Hourly Electricity Load Profile Using Neural Networks Mashud Rana and Irena Koprinska--We present INN, a new approach for predicting the hourly electricity load profile for the next day from a time series of previous electricity loads. It uses an iterative methodology to make the predictions

  13. Reinterpretation of the RRISP-77 Iceland Shear Wave Profiles

    E-Print Network [OSTI]

    Menke, William

    Reinterpretation of the RRISP-77 Iceland Shear Wave Profiles William Menke , Bryndís Brandsdóttir Sciences of Columbia University, Palisades NY 10964 USA £ Science Institute, University of Iceland Dunhagi 5, Reykjavík IS-107 Iceland SUMMARY Two shear wave profiles, E and G, collected during the 1977

  14. Reinterpretation of the RRISP77 Iceland Shear Wave Profiles

    E-Print Network [OSTI]

    Menke, William

    Reinterpretation of the RRISP­77 Iceland Shear Wave Profiles William Menke 1 , Bryndís Brandsdóttir. of Geological Sciences of Columbia University, Palisades NY 10964 USA 2 Science Institute, University of Iceland Dunhagi 5, Reykjavík IS­107 Iceland SUMMARY Two shear wave profiles, E and G, collected during the 1977

  15. Method and apparatus for measuring irradiated fuel profiles

    DOE Patents [OSTI]

    Lee, D.M.

    1980-03-27

    A new apparatus is used to substantially instantaneously obtain a profile of an object, for example a spent fuel assembly, which profile (when normalized) has unexpectedly been found to be substantially identical to the normalized profile of the burnup monitor Cs-137 obtained with a germanium detector. That profile can be used without normalization in a new method of identifying and monitoring in order to determine for example whether any of the fuel has been removed. Alternatively, two other new methods involve calibrating that profile so as to obtain a determination of fuel burnup (which is important for complying with safeguards requirements, for utilizing fuel to an optimal extent, and for storing spent fuel in a minimal amount of space).

  16. Performance profiles of major energy producers, 1997

    SciTech Connect (OSTI)

    1999-01-01

    The energy industry generally and petroleum and natural gas operations in particular are frequently reacting to a variety of unsettling forces. Falling oil prices, economic upswings, currency devaluations, increasingly rigorous environmental quality standards, deregulation of electricity markets, and continued advances in exploration and production technology were among the challenges and opportunities to the industry in 1997. To analyze the extent to which these and other developments have affected energy industry financial and operating performance, strategies, and industry structure, the Energy Information Administration (EIA) maintains the Financial Reporting Systems (FRS). Through Form EIA-28, major US energy companies annually report to the FRS. Financial and operating information is reported by major lines of business, including oil and gas production (upstream), petroleum refining and marketing (downstream), other energy operations, and nonenergy business. Performance Profiles of Major Producers 1997 examines the interplays of energy markets, companies` strategies, and government policies (in 1997 and in historical context) that gave rise to the results given here. The report also analyzes other key aspects of energy company financial performance as seen through the multifaceted lens provided by the FRS data and complementary data for industry overall. 41 figs., 77 tabs.

  17. Original article Beneficial effects of soluble epoxide hydrolase inhibitors in myocardial infarction

    E-Print Network [OSTI]

    Hammock, Bruce D.

    post MI. Using metabolomic profiling of the inflammatory lipid mediators, we documented a significant post MI. Published by Elsevier Inc. 1. Introduction Cardiovascular disease is the leading cause

  18. \\\\mi\\home\\gillow\\LaTeX\\Comp\\Safety\\Risk-Assessments\\Roof\\Sedum Roof Area Roof Access Risk Assessments 3th March 2014.docx `Sedum' Roof Area(s)/Roof Access Risk Assessments

    E-Print Network [OSTI]

    \\\\mi\\home\\gillow\\LaTeX\\Comp\\Safety\\Risk-Assessments\\Roof\\Sedum Roof Area Roof Access Risk Assessments 3th March 2014.docx `Sedum' Roof Area(s)/Roof Access Risk Assessments DEPARTMENT: Andrew Wiles March 2015 Brief description of area and location Roof tops, walkways, and Fire Route. Sedum' Roof Area

  19. 1.Physics Department, Colorado School of Mines, Golden, CO 2. National Renewable Energy Laboratory, Golden, CO 3. United Solar Ovonic, LLC Troy, MI, United States THERMAL ACTIVATION OF DEEP OXYGEN DEFECT FORMATION AND HYDROGEN EFFUSION

    E-Print Network [OSTI]

    1.Physics Department, Colorado School of Mines, Golden, CO 2. National Renewable Energy Laboratory, Golden, CO 3. United Solar Ovonic, LLC Troy, MI, United States BACKGROUND THERMAL ACTIVATION OF DEEP was partially supported by a DOE grant through United Solar Ovonics, Inc., under the Solar America Initiative

  20. Page 274 Courses: Chemistry (CHEM) Sonoma State University 2015-2016 Catalog CHeM 125A QuAntitAtive generAL CHeMiStry (5)

    E-Print Network [OSTI]

    Ravikumar, B.

    Page 274 Courses: Chemistry (CHEM) Sonoma State University 2015-2016 Catalog CHeM 125A QuAntitAtive generAL CHeMiStry (5) Lecture, 3 hours; discussion 1 hour; laboratory 3 hours (5 units). This one-year analytical general chemistry course is designed for freshmen Chemistry majors, Biochemistry majors, or others

  1. Propagation of trembling aspen and hybrid poplar for agroforestry: potential benefits of elevated CO2 in the greenhouse

    E-Print Network [OSTI]

    Macdonald, Ellen

    CO2 in the greenhouse Kendall A. Tupker, Barb R. Thomas* and S. Ellen Macdonald Department the usefulness of elevated CO2 in the greenhouse to aid in early selection of genotypes and in the propagation and reclamation across Canada. Introduction Understanding the effects of greenhouse propagation methods

  2. Impacts of Climate Change and Elevated CO2 on Sugar Beet Production in Northern and Central Italy

    E-Print Network [OSTI]

    above and below-ground crop growth and yield, soil water movement, and the effects of elevated CO2 and increased precipitation regimes were sufficient to overcome the negative effects on crop yields linked and harvest yields globally. However, the increases in temperature and changes in precipitation as- sociated

  3. Fire Safety Journal 41 (2006) 349363 On the trajectories of embers initially elevated or lofted by small scale

    E-Print Network [OSTI]

    Tse, Stephen D.

    2006-01-01

    Fire Safety Journal 41 (2006) 349­363 On the trajectories of embers initially elevated or lofted by small scale ground fire plumes in high winds$ Ralph A. Antheniena,Ã, Stephen D. Tseb , A. Carlos are destroyed annually by wildfires. With many of these fires extending long distances due to spotting, detailed

  4. U-264: Apple OS X Lets Remote Users Execute Arbitrary Code and Local Users Gain Elevated Privileges

    Broader source: Energy.gov [DOE]

    Several vulnerabilities were reported in Apple OS X. A remote user can execute arbitrary code on the target system. A remote user can obtain a password hash in certain cases. A local user can obtain elevated privileges on the target system. A local user can obtain password keystrokes.

  5. Impacts of elevated CO2 and O3 on aspen leaf litter chemistry and earthworm and springtail productivity

    E-Print Network [OSTI]

    Impacts of elevated CO2 and O3 on aspen leaf litter chemistry and earthworm and springtail few studies have considered how CO2- and O3-induced changes in litter quality will affect decomposition. Although the fraction of litter carbon respired by soil invertebrates is fairly small

  6. Root responses along a subambient to elevated CO2 gradient in a C3C4 grassland

    E-Print Network [OSTI]

    Jackson, Robert B.

    Root responses along a subambient to elevated CO2 gradient in a C3­C4 grassland L A U R E L J . A N C3­C4 grassland exposed to a gradient of Ca from preglacial to future levels (230­550 lmol molÀ1 studies have docu- mented increases in belowground plant productivity and metabolism with increased

  7. Snow water equivalent along elevation gradients in the Merced and Tuolumne River basins of the Sierra Nevada

    E-Print Network [OSTI]

    Dozier, Jeff

    Snow water equivalent along elevation gradients in the Merced and Tuolumne River basins fractional snow-covered area (SCA) at 500 m resolution to estimate snow water equivalent (SWE) across) blending the fractional SCA with SWE interpolated from snow-pillow measurements; and (2) retrospectively

  8. Fracture and Fatigue Behavior at Ambient and Elevated Temperatures of Alumina Bonded with Copper/Niobium/Copper Interlayers

    E-Print Network [OSTI]

    Ritchie, Robert

    Fracture and Fatigue Behavior at Ambient and Elevated Temperatures of Alumina Bonded with Copper and Engineering, University of California, Berkeley, California 94720 Interfacial fracture toughness and cyclic temperatures, and assessed in terms of interfacial chemistry and microstructure. The mean interfacial fracture

  9. Numerical and experimental study of soot formation in laminar diffusion flames burning simulated biogas fuels at elevated pressures

    E-Print Network [OSTI]

    Gülder, Ömer L.

    biogas fuels at elevated pressures Marc R.J. Charest , Ömer L. Gülder, Clinton P.T. Groth University 18 April 2014 Available online 2 June 2014 Keywords: Soot formation High pressure combustion Biogas, and other chemical species that are harmful to human health and the environment. Gaseous biofuels, or biogas

  10. Summary Elevated concentrations of atmospheric carbon dioxide ([CO2]) and tropospheric ozone ([O3]) have the poten-

    E-Print Network [OSTI]

    Summary Elevated concentrations of atmospheric carbon dioxide ([CO2]) and tropospheric ozone ([O3 gases (greenhouse gases) altered by human activities (IPCC 2007), only carbon dioxide (CO2 vegeta- tion properties affect local and regional climate, as well as how atmospheric forcing

  11. Bayesian models for elevated disease risk due to exposure to uranium mine and mill waste on the Navajo Nation

    E-Print Network [OSTI]

    Huerta, Gabriel

    ForReview Only Bayesian models for elevated disease risk due to exposure to uranium mine and mill of Pharmacy, Community Environmental Health Program Keywords: abandoned uranium mines, conditionally specified to ex- posure to uranium mine and mill waste on the Navajo Nation Glenn A. Stark University of New

  12. ICELANDIC RHYTHMICS: ANNUAL MODULATION OF LAND ELEVATION AND PLATE SPREADING BY SNOW LOAD (AGU G33B-0055)

    E-Print Network [OSTI]

    Grapenthin, Ronni

    ICELANDIC RHYTHMICS: ANNUAL MODULATION OF LAND ELEVATION AND PLATE SPREADING BY SNOW LOAD (AGU ­ G Volcanological Center, Institute of Earth Sciences, University of Iceland, Reykjavik, Iceland 2 Icelandic Meteorological Office, Reykjavik, Iceland 3 IRD, UMR5559, Laboratoire de Geophysique Interne et Tectonophysique

  13. PUBLISHED ONLINE: 2 NOVEMBER 2014 | DOI: 10.1038/NGEO2284 Plant growth enhancement by elevated CO2

    E-Print Network [OSTI]

    Thomas, David D.

    by elevated CO2 eliminated by joint water and nitrogen limitation Peter B. Reich1,2 *, Sarah E. Hobbie3 and Tali D. Lee4 Rising atmospheric CO2 concentrations can fertilize plant growth. The resulting increased plant uptake of CO2 could, in turn, slow increases in atmospheric CO2 levels and associated climate

  14. Electrochemical and physical analysis of a Li-ion cell cycled at elevated temperature

    SciTech Connect (OSTI)

    Shim, Joongpyo; Kostecki, Robert; Richardson, Thomas; Song, Xiangyun; Striebel, Kathryn A.

    2002-06-21

    Laboratory-size LiNi0.8Co0.15Al0.05O2/graphite lithium-ion pouch cells were cycled over 100 percent DOD at room temperature and 60 degrees C in order to investigate high-temperature degradation mechanisms of this important technology. Capacity fade for the cell was correlated with that for the individual components, using electrochemical analysis of the electrodes and other diagnostic techniques. The high-temperature cell lost 65 percent of its initial capacity after 140 cycles at 60 degrees C compared to only 4 percent loss for the cell cycled at room temperature. Cell ohmic impedance increased significantly with the elevated temperature cycling, resulting in some of loss of capacity at the C/2 rate. However, as determined with slow rate testing of the individual electrodes, the anode retained most of its original capacity, while the cathode lost 65 percent, even when cycled with a fresh source of lithium. Diagnostic evaluation of cell components including XRD, Raman, CSAFM and suggest capacity loss occurs primarily due to a rise in the impedance of the cathode, especially at the end-of-charge. The impedance rise may be caused in part by a loss of the conductive carbon at the surface of the cathode and/or by an organic film on the surface of the cathode that becomes non-ionically conductive at low lithium content.

  15. CHARACTERIZATION OF ELEVATED TEMPERATURE PROPERTIES OF HEAT EXCHANGER AND STEAM GENERATOR ALLOYS

    SciTech Connect (OSTI)

    J.K. Wright; L.J. Carroll; C.J. Cabet; T. Lillo; J.K. Benz; J.A. Simpson; A. Chapman; R.N. Wright

    2012-10-01

    The Next Generation Nuclear Plant project is considering Alloy 800H and Alloy 617 for steam generator and intermediate heat exchangers. It is envisioned that a steam generator would operate with reactor outlet temperatures from 750 to 800 C, while an intermediate heat exchanger for primary to secondary helium would operate up to an outlet temperature of 950 C. Although both alloys are of interest due in part to their technical maturity, a number of specific properties require further characterization for design of nuclear components. Strain rate sensitivity of both alloys has been characterized and is found to be significant above 600 C. Both alloys also exhibit dynamic strain aging, characterized by serrated flow, over a wide range of temperatures and strain rates. High temperature tensile testing of Alloy 617 has been conducted over a range of temperatures. Dynamic strain aging is a concern for these materials since it is observed to result in reduced ductility for many solid solution alloys. Creep, fatigue, and creep-fatigue properties of Alloy 617 have been measured as well, with the goal of determining the influence of the temperature, strain rate and atmosphere on the creep fatigue life of Alloy 617. Elevated temperature properties and implications for codification of the alloys will be described.

  16. Processes regulating progressive nitrogen limitation under elevated carbon dioxide: a meta-analysis

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Liang, J.; Qi, X.; Souza, L.; Luo, Y.

    2015-10-20

    Nitrogen (N) cycle has the potential to regulate climate change through its influence on carbon (C) sequestration. Although extensive researches have been done to explore whether or not progressive N limitation (PNL) occurs under CO2 enrichment, a comprehensive assessment of the processes that regulate PNL is still lacking. Here, we quantitatively synthesized the responses of all major processes and pools in terrestrial N cycle with meta-analysis of CO2 experimental data available in the literature. The results showed that CO2 enrichment significantly increased N sequestration in plant and litter pools but not in soil pool. Thus, the basis of PNL occurrencemore »partially exists. However, CO2 enrichment also significantly increased the N influx via biological N fixation, but decreased the N efflux via leaching. In addition, no general diminished CO2 fertilization effect on plant growth over time was observed. Overall, our analyses suggest that the extra N supply by the increased biological N fixation and decreased leaching may potentially alleviate PNL under elevated CO2 conditions. Moreover, our synthesis showed that CO2 enrichment increased soil ammonium (NH4+) but decreased nitrate (NO3-). The different responses of NH4+ and NO3-, and the consequent biological processes, may result in changes in soil microenvironment, community structures and above-belowground interactions, which could potentially affect the terrestrial biogeochemical cycles and the feedback to climate change.« less

  17. Building America Top Innovations 2013 Profile – Buried and Encapsulated Ducts

    SciTech Connect (OSTI)

    2013-09-01

    In this innovation profile, CARB research shows HVAC ducts that are encapsulated in closed-cell spray foam and buried in blown insulation in a vented attic meet the code requirements for ducts in conditioned space.

  18. Profiling the Thermoelectric Power of Semiconductor Junctions with

    E-Print Network [OSTI]

    components or hazardous working fluids. Developing new thermoelectric mate- rials with high figures of merit S is governed by local carrier statistics, SThEM allows us to profile precise elec- tronic junction locations

  19. Evolving Musical Performance Profiles Using Genetic Algorithms with Structural Fitness

    E-Print Network [OSTI]

    Miranda, Eduardo Reck

    Evolving Musical Performance Profiles Using Genetic Algorithms with Structural Fitness Qijun Zhang Eduardo Reck Miranda Computer Music Research School of Computing, communications and Electronics.e., hierarchical duration vs. amplitude matrices) for expressive music performance by machines. The performance

  20. Informao Confidencial e Proprietria Confidential and Proprietary Information Company Profile

    E-Print Network [OSTI]

    Informação Confidencial e Proprietária Confidential and Proprietary Information Company Profile Information 2 Summary (I) Company Facts (II) Company Capabilities (III) Projects & Products (IV) On Information (I) Company Facts #12;26-Aug-2010 4 Informação Confidencial e Proprietária Confidential