National Library of Energy BETA

Sample records for mechanical problems repairs

  1. Extended mechanical stimulations of cartilage for growth and repair

    E-Print Network [OSTI]

    Lee, Gary C. (Gary Chiaray), 1980-

    2004-01-01

    Extended mechanical stimulation of articular cartilage in an in vitro model explant system promotes growth and repair. An alternating day mechanical loading protocol consisting of dynamic sinusoidal compression results in ...

  2. CLASSICAL MECHANICS: THE THREE-BODY PROBLEM ZI CHONG KAO

    E-Print Network [OSTI]

    May, J. Peter

    CLASSICAL MECHANICS: THE THREE-BODY PROBLEM ZI CHONG KAO Abstract. The Three-Body Problem is one of the oldest unsolved problems of classical mechanics. It arose as a natural extension of the Two-Body Prob of numerous techniques in classical mechan- ics as well as dynamical systems. Understanding the Three

  3. INTERNAL REPAIR OF PIPELINES

    SciTech Connect (OSTI)

    Bill Bruce; Nancy Porter; George Ritter; Matt Boring; Mark Lozev; Ian Harris; Bill Mohr; Dennis Harwig; Robin Gordon; Chris Neary; Mike Sullivan

    2005-07-20

    The two broad categories of fiber-reinforced composite liner repair and deposited weld metal repair technologies were reviewed and evaluated for potential application for internal repair of gas transmission pipelines. Both are used to some extent for other applications and could be further developed for internal, local, structural repair of gas transmission pipelines. Principal conclusions from a survey of natural gas transmission industry pipeline operators can be summarized in terms of the following performance requirements for internal repair: (1) Use of internal repair is most attractive for river crossings, under other bodies of water, in difficult soil conditions, under highways, under congested intersections, and under railway crossings. (2) Internal pipe repair offers a strong potential advantage to the high cost of horizontal direct drilling when a new bore must be created to solve a leak or other problem. (3) Typical travel distances can be divided into three distinct groups: up to 305 m (1,000 ft.); between 305 m and 610 m (1,000 ft. and 2,000 ft.); and beyond 914 m (3,000 ft.). All three groups require pig-based systems. A despooled umbilical system would suffice for the first two groups which represents 81% of survey respondents. The third group would require an onboard self-contained power unit for propulsion and welding/liner repair energy needs. (4) The most common size range for 80% to 90% of operators surveyed is 508 mm (20 in.) to 762 mm (30 in.), with 95% using 558.8 mm (22 in.) pipe. Evaluation trials were conducted on pipe sections with simulated corrosion damage repaired with glass fiber-reinforced composite liners, carbon fiber-reinforced composite liners, and weld deposition. Additional un-repaired pipe sections were evaluated in the virgin condition and with simulated damage. Hydrostatic failure pressures for pipe sections repaired with glass fiber-reinforced composite liner were only marginally greater than that of pipe sections without liners, indicating that this type of liner is only marginally effective at restoring the pressure containing capabilities of pipelines. Failure pressures for larger diameter pipe repaired with a semi-circular patch of carbon fiber-reinforced composite lines were also marginally greater than that of a pipe section with un-repaired simulated damage without a liner. These results indicate that fiber reinforced composite liners have the potential to increase the burst pressure of pipe sections with external damage Carbon fiber based liners are viewed as more promising than glass fiber based liners because of the potential for more closely matching the mechanical properties of steel. Pipe repaired with weld deposition failed at pressures lower than that of un-repaired pipe in both the virgin and damaged conditions, indicating that this repair technology is less effective at restoring the pressure containing capability of pipe than a carbon fiber-reinforced liner repair. Physical testing indicates that carbon fiber-reinforced liner repair is the most promising technology evaluated to-date. In lieu of a field installation on an abandoned pipeline, a preliminary nondestructive testing protocol is being developed to determine the success or failure of the fiber-reinforced liner pipeline repairs. Optimization and validation activities for carbon-fiber repair methods are ongoing.

  4. INTERNAL REPAIR OF PIPELINES

    SciTech Connect (OSTI)

    Robin Gordon; Bill Bruce; Ian Harris; Dennis Harwig; George Ritter; Bill Mohr; Matt Boring; Nancy Porter; Mike Sullivan; Chris Neary

    2004-12-31

    The two broad categories of fiber-reinforced composite liner repair and deposited weld metal repair technologies were reviewed and evaluated for potential application for internal repair of gas transmission pipelines. Both are used to some extent for other applications and could be further developed for internal, local, structural repair of gas transmission pipelines. Principal conclusions from a survey of natural gas transmission industry pipeline operators can be summarized in terms of the following performance requirements for internal repair: (1) Use of internal repair is most attractive for river crossings, under other bodies of water, in difficult soil conditions, under highways, under congested intersections, and under railway crossings. (2) Internal pipe repair offers a strong potential advantage to the high cost of horizontal direct drilling when a new bore must be created to solve a leak or other problem. (3) Typical travel distances can be divided into three distinct groups: up to 305 m (1,000 ft.); between 305 m and 610 m (1,000 ft. and 2,000 ft.); and beyond 914 m (3,000 ft.). All three groups require pig-based systems. A despooled umbilical system would suffice for the first two groups which represents 81% of survey respondents. The third group would require an onboard self-contained power unit for propulsion and welding/liner repair energy needs. (4) The most common size range for 80% to 90% of operators surveyed is 508 mm (20 in.) to 762 mm (30 in.), with 95% using 558.8 mm (22 in.) pipe. Evaluation trials were conducted on pipe sections with simulated corrosion damage repaired with glass fiber-reinforced composite liners, carbon fiber-reinforced composite liners, and weld deposition. Additional un-repaired pipe sections were evaluated in the virgin condition and with simulated damage. Hydrostatic failure pressures for pipe sections repaired with glass fiber-reinforced composite liner were only marginally greater than that of pipe sections without liners, indicating that this type of liner is only marginally effective at restoring the pressure containing capabilities of pipelines. Failure pressures for larger diameter pipe repaired with a semi-circular patch of carbon fiber-reinforced composite lines were also marginally greater than that of a pipe section with un-repaired simulated damage without a liner. These results indicate that fiber reinforced composite liners have the potential to increase the burst pressure of pipe sections with external damage Carbon fiber based liners are viewed as more promising than glass fiber based liners because of the potential for more closely matching the mechanical properties of steel. Pipe repaired with weld deposition failed at pressures lower than that of un-repaired pipe in both the virgin and damaged conditions, indicating that this repair technology is less effective at restoring the pressure containing capability of pipe than a carbon fiber-reinforced liner repair. Physical testing indicates that carbon fiber-reinforced liner repair is the most promising technology evaluated to-date. The first round of optimization and validation activities for carbon-fiber repairs are complete. Development of a comprehensive test plan for this process is recommended for use in the field trial portion of this program.

  5. INTERNAL REPAIR OF PIPELINES

    SciTech Connect (OSTI)

    Robin Gordon; Bill Bruce; Ian Harris; Dennis Harwig; George Ritter; Bill Mohr; Matt Boring; Nancy Porter; Mike Sullivan; Chris Neary

    2004-08-17

    The two broad categories of fiber-reinforced composite liner repair and deposited weld metal repair technologies were reviewed and evaluated for potential application for internal repair of gas transmission pipelines. Both are used to some extent for other applications and could be further developed for internal, local, structural repair of gas transmission pipelines. Principal conclusions from a survey of natural gas transmission industry pipeline operators can be summarized in terms of the following performance requirements for internal repair: (1) Use of internal repair is most attractive for river crossings, under other bodies of water, in difficult soil conditions, under highways, under congested intersections, and under railway. (2) Internal pipe repair offers a strong potential advantage to the high cost of horizontal direct drilling when a new bore must be created to solve a leak or other problem. (3) Typical travel distances can be divided into three distinct groups: up to 305 m (1,000 ft.); between 305 m and 610 m (1,000 ft. and 2,000 ft.); and beyond 914 m (3,000 ft.). All three groups require pig-based systems. A despooled umbilical system would suffice for the first two groups which represents 81% of survey respondents. The third group would require an onboard self-contained power unit for propulsion and welding/liner repair energy needs. (4) The most common size range for 80% to 90% of operators surveyed is 508 mm (20 in.) to 762 mm (30 in.), with 95% using 558.8 mm (22 in.) pipe. Evaluation trials were conducted on pipe sections with simulated corrosion damage repaired with glass fiber-reinforced composite liners, carbon fiber-reinforced composite liners, and weld deposition. Additional un-repaired pipe sections were evaluated in the virgin condition and with simulated damage. Hydrostatic failure pressures for pipe sections repaired with glass fiber-reinforced composite liner were only marginally greater than that of pipe sections without liners, indicating that this type of liner is only marginally effective at restoring the pressure containing capabilities of pipelines. Failure pressures for larger diameter pipe repaired with a semi-circular patch of carbon fiber-reinforced composite lines were also marginally greater than that of a pipe section with un-repaired simulated damage without a liner. These results indicate that fiber reinforced composite liners have the potential to increase the burst pressure of pipe sections with external damage Carbon fiber based liners are viewed as more promising than glass fiber based liners because of the potential for more closely matching the mechanical properties of steel. Pipe repaired with weld deposition failed at pressures lower than that of un-repaired pipe in both the virgin and damaged conditions, indicating that this repair technology is less effective at restoring the pressure containing capability of pipe than a carbon fiber-reinforced liner repair. Physical testing indicates that carbon fiber-reinforced liner repair is the most promising technology evaluated to-date. Development of a comprehensive test plan for this process is recommended for use in the field trial portion of this program.

  6. Mechanical engineering Mechanical engineering is about solving problems, designing processes,

    E-Print Network [OSTI]

    Waikato, University of

    , from power stations to cars, robots and computers. The professional training mechanical engineers such as aerospace, automotive, dairy, energy, product and plant design, pulp and paper, as well as shipping,as well as virtual reality and entertainment. MaterialS & ProceSS engineering This programme focuses

  7. Challenge Problem: Agent-Mediated Decentralized Information Mechanisms

    E-Print Network [OSTI]

    Chen, Yiling

    , data degra- dation, and information aggregation; and (3) reputation mechanisms to address asymmetriesChallenge Problem: Agent-Mediated Decentralized Information Mechanisms David C. Parkes Division the opportunities, such as for data mining and collaborative filtering, and the dangers, such as for privacy abuse

  8. A Pedestrian Approach to the Measurement Problem in Quantum Mechanics

    E-Print Network [OSTI]

    Boughn, Stephen

    2013-01-01

    The quantum theory of measurement has been a matter of debate for over eighty years. Most of the discussion has focused on theoretical issues with the consequence that operational prescriptions, which are integral to experimental physics, have been largely ignored. This has undoubtedly exacerbated attempts to find a solution to the "measurement problem". In this paper, we fully embrace the ensemble interpretation of quantum mechanics that obviates the need to entertain reduction of the state vector, one of the primary dilemmas of the measurement problem. The other major aspect of the measurement problem, the necessity of describing measurements in terms of classical concepts, remains. However, we argue that the ultimate interface with experiments is described by operational prescriptions and not in terms of the concepts of classical theory. The pedestrian approach presented here suggests that the measurement problem is, in some sense, ill-posed and might never be resolved. This state of affairs is, in part, t...

  9. A Pedestrian Approach to the Measurement Problem in Quantum Mechanics

    E-Print Network [OSTI]

    Stephen Boughn; Marcel Reginatto

    2013-09-03

    The quantum theory of measurement has been a matter of debate for over eighty years. Most of the discussion has focused on theoretical issues with the consequence that operational prescriptions, which are integral to experimental physics, have been largely ignored. This has undoubtedly exacerbated attempts to find a solution to the "measurement problem". In this paper, we fully embrace the ensemble interpretation of quantum mechanics that obviates the need to entertain reduction of the state vector, one of the primary dilemmas of the measurement problem. The other major aspect of the measurement problem, the necessity of describing measurements in terms of classical concepts, remains. However, we argue that the ultimate interface with experiments is described by operational prescriptions and not in terms of the concepts of classical theory. The pedestrian approach presented here suggests that the measurement problem is, in some sense, ill-posed and might never be resolved. This state of affairs is, in part, the result of searching for a theoretical answer to what is fundamentally an experimental question. This point of view is tenable so long as one is willing to view physical theories as providing models of nature rather than complete descriptions of reality. Among other things, these considerations lead us to suggest that the Copenhagen interpretation's insistence on the classicality of the measurement apparatus should be replaced by the requirement that a measurement, which is specified operationally, should simply be of sufficient precision.

  10. Comparison of problem model change mechanisms issued from CSP and TRIZ

    E-Print Network [OSTI]

    Paris-Sud XI, Universitť de

    1 Comparison of problem model change mechanisms issued from CSP and TRIZ RRoollaanndd DDee GGuuiioo satisfaction problem (CSP), on the other hand. Keywords: over-constrained problems, dialectical methods issued from CSP and TRIZ 2 ∑ a set of evaluation parameters, which represent the objective of the problem

  11. Irrational Dynamical Variables and the Measurement Problem in Quantum Mechanics

    E-Print Network [OSTI]

    Christopher Engelhardt

    2015-07-08

    The quantum mechanical measurement process is considered. A hypothetical concept of irrational dynamical variables is proposed. A possible definition of measurement is discussed along with a mathematical method to calculate experimental result probabilities. The postulates of quantum mechanics are analyzed and modified. Thought experiments and implications are considered.

  12. Low Dose Radiation-Induced Genome and Epigenome Instability Symposium and Epigenetic Mechanisms, DNA Repair, and Chromatin Symposium at the EMS 2008 Annual Meeting - October 2008

    SciTech Connect (OSTI)

    Morgan, William F.; Kovalchuk, Olga; Dolinoy, Dana C.; Dubrova, Yuri E.; Coleman, Matthew A.; Schšr, Primo; Pogribny, Igor; Hendzel, Michael

    2010-02-19

    The Low Dose Radiation Symposium thoughtfully addressed ionizing radiation non-mutational but transmissable alterations in surviving cells. Deregulation of epigenetic processes has been strongly implicated in carcinogenesis, and there is increasing realization that a significant fraction of non-targeted and adaptive mechanisms in response to ionizing radiation are likely to be epigenetic in nature. Much remains to be learned about how chromatin and epigenetic regulators affect responses to low doses of radiation, and how low dose radiation impacts other epigenetic processes. The Epigenetic Mechanisms Symposium focused on on epigenetic mechanisms and their interplay with DNA repair and chromatin changes. Addressing the fact that the most well understood mediators of epigenetic regulation are histone modifications and DNA methylation. Low levels of radiation can lead to changes in the methylation status of certain gene promoters and the expression of DNA methyltransferases, However, epigenetic regulation can also involve changes in higher order chromosome structure.

  13. Design and Evaluation of Problem Solving Courseware Modules For Mechanics of Materials

    E-Print Network [OSTI]

    Steif, Paul

    1 Design and Evaluation of Problem Solving Courseware Modules For Mechanics of Materials Paul S Evaluation Consultant Abstract Problem solving courseware modules have been developed for students sense of the meaning of key quantities, and fluency in using relations to solve problems. Students use

  14. Groupstrategyproofness of the Egalitarian Mechanism for Constrained Rationing Problems

    E-Print Network [OSTI]

    Chandramouli, Shyam S

    2011-01-01

    The key contribution of the paper is a comprehensive study of the egalitarian mechanism with respect to manipulation by a coalition of agents. Our main result is that the egalitarian mechanism is, in fact, peak group strategyproof : no coalition of agents can (weakly) benefit from jointly misreporting their peaks. Furthermore, we show that the egalitarian mechanism cannot be manipulated by any coalition of suppliers (or any coalition of demanders) in the model where both the suppliers and demanders are agents. Our proofs shed light on the structure of the two models and simpify some of the earlier proofs of strategyproofness in the earlier papers. An implication of our results is that the well known algorithm of Megiddo to compute a lexicographically optimal flow in a network is group strategyproof with respect to the source capacities (or sink capacities).

  15. INTERNAL REPAIR OF PIPELINES

    SciTech Connect (OSTI)

    Robin Gordon; Bill Bruce; Ian Harris; Dennis Harwig; Nancy Porter; Mike Sullivan; Chris Neary

    2004-04-12

    The two broad categories of deposited weld metal repair and fiber-reinforced composite liner repair technologies were reviewed for potential application for internal repair of gas transmission pipelines. Both are used to some extent for other applications and could be further developed for internal, local, structural repair of gas transmission pipelines. Preliminary test programs were developed for both deposited weld metal repair and for fiber-reinforced composite liner repair. Evaluation trials have been conducted using a modified fiber-reinforced composite liner provided by RolaTube and pipe sections without liners. All pipe section specimens failed in areas of simulated damage. Pipe sections containing fiber-reinforced composite liners failed at pressures marginally greater than the pipe sections without liners. The next step is to evaluate a liner material with a modulus of elasticity approximately 95% of the modulus of elasticity for steel. Preliminary welding parameters were developed for deposited weld metal repair in preparation of the receipt of Pacific Gas & Electric's internal pipeline welding repair system (that was designed specifically for 559 mm (22 in.) diameter pipe) and the receipt of 559 mm (22 in.) pipe sections from Panhandle Eastern. The next steps are to transfer welding parameters to the PG&E system and to pressure test repaired pipe sections to failure. A survey of pipeline operators was conducted to better understand the needs and performance requirements of the natural gas transmission industry regarding internal repair. Completed surveys contained the following principal conclusions: (1) Use of internal weld repair is most attractive for river crossings, under other bodies of water, in difficult soil conditions, under highways, under congested intersections, and under railway crossings. (2) Internal pipe repair offers a strong potential advantage to the high cost of horizontal direct drilling (HDD) when a new bore must be created to solve a leak or other problem. (3) Typical travel distances can be divided into three distinct groups: up to 305 m (1,000 ft.); between 305 m and 610 m (1,000 ft. and 2,000 ft.); and beyond 914 m (3,000 ft.). All three groups require pig-based systems. A despooled umbilical system would suffice for the first two groups which represents 81% of survey respondents. The third group would require an onboard self-contained power unit for propulsion and welding/liner repair energy needs. (4) Pipe diameter sizes range from 50.8 mm (2 in.) through 1,219.2 mm (48 in.). The most common size range for 80% to 90% of operators surveyed is 508 mm to 762 mm (20 in. to 30 in.), with 95% using 558.8 mm (22 in.) pipe. An evaluation of potential repair methods clearly indicates that the project should continue to focus on the development of a repair process involving the use of GMAW welding and on the development of a repair process involving the use of fiber-reinforced composite liners.

  16. Multiscale treatment of mechanical contact problems involving thin polymeric layers

    E-Print Network [OSTI]

    ) and nanoelectromechanical (NEMS) systems for industrial applications [1]. This field is concerned with the study of energy wasted because of friction, which occurs in particular between mechanical components such as gears and bearings. Hence it greatly influences the design of devices containing moving parts, like motors and hard

  17. The extension problem for partial Boolean structures in Quantum Mechanics

    E-Print Network [OSTI]

    Costantino Budroni; Giovanni Morchio

    2011-01-13

    Alternative partial Boolean structures, implicit in the discussion of classical representability of sets of quantum mechanical predictions, are characterized, with definite general conclusions on the equivalence of the approaches going back to Bell and Kochen-Specker. An algebraic approach is presented, allowing for a discussion of partial classical extension, amounting to reduction of the number of contexts, classical representability arising as a special case. As a result, known techniques are generalized and some of the associated computational difficulties overcome. The implications on the discussion of Boole-Bell inequalities are indicated.

  18. The extension problem for partial Boolean structures in Quantum Mechanics

    E-Print Network [OSTI]

    Budroni, Costantino

    2010-01-01

    Alternative partial Boolean structures, implicit in the discussion of classical representability of sets of quantum mechanical predictions, are characterized, with definite general conclusions on the equivalence of the approaches going back to Bell and Kochen-Specker. An algebraic approach is presented, allowing for a discussion of partial classical extension, amounting to reduction of the number of contexts, classical representability arising as a special case. As a result, known techniques are generalized and some of the associated computational difficulties overcome. The implications on the discussion of Boole-Bell inequalities are indicated.

  19. Statistical Mechanics of the vertexcover problem Alexander K. Hartmann and Martin Weigt

    E-Print Network [OSTI]

    Hartmann, Alexander K.

    Statistical Mechanics of the vertex¬≠cover problem Alexander K. Hartmann and Martin Weigt Institute for Theoretical Physics, University of Gň?ottingen, Bunsenstr. 9, 37073 Gň?ottingen, Germany E¬≠mail: hartmann

  20. On inverse problems in electromagnetic field in classical mechanics at fixed energy

    E-Print Network [OSTI]

    Alexandre Jollivet

    2007-01-04

    In this paper, we consider inverse scattering and inverse boundary value problems at sufficiently large and fixed energy for the multidimensional relativistic and nonrelativistic Newton equations in a static external electromagnetic field $(V,B)$, $V\\in C^2,$ $B\\in C^1$ in classical mechanics. Developing the approach going back to Gerver-Nadirashvili 1983's work on an inverse problem of mechanics, we obtain, in particular, theorems of uniqueness.

  1. Turbine repair process, repaired coating, and repaired turbine component

    SciTech Connect (OSTI)

    Das, Rupak; Delvaux, John McConnell; Garcia-Crespo, Andres Jose

    2015-11-03

    A turbine repair process, a repaired coating, and a repaired turbine component are disclosed. The turbine repair process includes providing a turbine component having a higher-pressure region and a lower-pressure region, introducing particles into the higher-pressure region, and at least partially repairing an opening between the higher-pressure region and the lower-pressure region with at least one of the particles to form a repaired turbine component. The repaired coating includes a silicon material, a ceramic matrix composite material, and a repaired region having the silicon material deposited on and surrounded by the ceramic matrix composite material. The repaired turbine component a ceramic matrix composite layer and a repaired region having silicon material deposited on and surrounded by the ceramic matrix composite material.

  2. Asymptotic Methods for PDE Problems in Fluid Mechanics and Related Systems

    E-Print Network [OSTI]

    Ward, Michael Jeffrey

    Perturbations in Two-Dimensional Domains Michael J. Ward (UBC) CISM Advanced Course; Asymptotic Methods in Fluid Mechanics: Surveys and Recent Advances Lecture III: A Range of Miscellaneous Problems CISM ≠ p.1 #12;Outline Contexts CISM ≠ p.2 #12;Slow Viscous Flow Over a Cylinder Consider slow, steady, two-dimensional flow

  3. INTERNAL REPAIR OF PIPELINES

    SciTech Connect (OSTI)

    Robin Gordon; Bill Bruce; Nancy Porter; Mike Sullivan; Chris Neary

    2003-05-01

    The two broad categories of deposited weld metal repair and fiber-reinforced composite repair technologies were reviewed for potential application for internal repair of gas transmission pipelines. Both are used to some extent for other applications and could be further developed for internal, local, structural repair of gas transmission pipelines. Preliminary test programs were developed for both deposited weld metal repairs and for fiber-reinforced composite repair. To date, all of the experimental work pertaining to the evaluation of potential repair methods has focused on fiber-reinforced composite repairs. Hydrostatic testing was also conducted on four pipeline sections with simulated corrosion damage: two with composite liners and two without.

  4. Rapid road repair vehicle

    DOE Patents [OSTI]

    Mara, Leo M. (Livermore, CA)

    1998-01-01

    Disclosed is a rapid road repair vehicle capable of moving over a surface to be repaired at near normal posted traffic speeds to scan for and find an the high rate of speed, imperfections in the pavement surface, prepare the surface imperfection for repair by air pressure and vacuum cleaning, applying a correct amount of the correct patching material to effect the repair, smooth the resulting repaired surface, and catalog the location and quality of the repairs for maintenance records of the road surface. The rapid road repair vehicle can repair surface imperfections at lower cost, improved quality, at a higher rate of speed than was was heretofor possible, with significantly reduced exposure to safety and health hazards associated with this kind of road repair activities in the past.

  5. Rapid road repair vehicle

    DOE Patents [OSTI]

    Mara, L.M.

    1998-05-05

    Disclosed is a rapid road repair vehicle capable of moving over a surface to be repaired at near normal posted traffic speeds to scan for and find at the high rate of speed, imperfections in the pavement surface, prepare the surface imperfection for repair by air pressure and vacuum cleaning, applying a correct amount of the correct patching material to effect the repair, smooth the resulting repaired surface, and catalog the location and quality of the repairs for maintenance records of the road surface. The rapid road repair vehicle can repair surface imperfections at lower cost, improved quality, at a higher rate of speed than was not heretofor possible, with significantly reduced exposure to safety and health hazards associated with this kind of road repair activities in the past. 2 figs.

  6. The effect of giving explicit incentives to correct mistakes on subsequent problem solving in quantum mechanics

    E-Print Network [OSTI]

    Brown, Benjamin; Singh, Chandralekha

    2015-01-01

    One attribute of experts is that they are likely to learn from their own mistakes. Experts are unlikely to make the same mistakes when asked to solve a problem a second time, especially if they had access to a correct solution. Here, we discuss a study spanning several years in which advanced undergraduate physics students in a quantum mechanics course were given incentives to correct their mistakes in the midterm exam and they could get back up to 50% of the points lost on each midterm exam problem. The solutions to the midterm exam problems were provided to all students in both groups but those who corrected their mistakes were provided the solution after they submitted their corrections to the instructor. The performance on the final exam on the same problems suggests that students who were given incentives to correct their mistakes significantly outperformed those who were not given an incentive. The incentive to correct mistakes had the greatest impact on the final exam performance of students who perfor...

  7. Statistical mechanics problem sheet 7 1. The main component of Venus's atmosphere, carbon dioxide, is a linear molecule

    E-Print Network [OSTI]

    Dettmann, Carl

    Statistical mechanics problem sheet 7 1. The main component of Venus's atmosphere, carbon dioxide and energy. Show that the system is non-extensive, and find the chemical potential at which system properties

  8. A mechanical engineer's approach to the measurement problem: Is a picture worth a thousand words?

    E-Print Network [OSTI]

    Fred H. Thaheld

    2009-09-08

    The measurement problem is approached from a mechanical aspect, utilizing schematics to better assist in visualizing the boundary and the interplay between the quantum and classical worlds. This approach graphically illustrates what happens when a photon is absorbed by the retinal molecule, and reveals that even after collapse of the wave function, the information previously carried by the photon and passed on to the pi* electron, is still at the microscopic level waiting to be amplified up to the macroscopic level by the rod cell. This analysis reveals that the measuring device or detector is of an unusual 2-stage nature, consisting of a microscopic entity or rhodopsin molecule which is not affected by the environment, contained within a macroscopic rod cell which serves as an amplifier. This approach may also allow one to better visualize the boundary conditions just prior to collapse and whether it is necessary to make any kind of adjustment to the Schroedinger equation to achieve a nonlinear collapse.

  9. The Quantum Mechanics Problem of the Schroedinger Equation with the Trigonometric Rosen-Morse Potential

    E-Print Network [OSTI]

    C. B. Compean; M. Kirchbach

    2006-03-26

    We present the quantum mechanics problem of the one-dimensional Schroedinger equation with the trigonometric Rosen-Morse potential. This potential is of possible interest to quark physics in so far as it captures the essentials of the QCD quark-gluon dynamics and (i) interpolates between a Coulomb-like potential (associated with one-gluon exchange) and the infinite wall potential (associated with asymptotic freedom), (ii) reproduces in the intermediary region the linear confinement potential (associated with multi-gluon self-interactions) as established by lattice QCD calculations of hadron properties. Moreover, its exact real solutions given here display a new class of real orthogonal polynomials and thereby interesting mathematical entities in their own.

  10. The Relation Between Reasoning and the Structure of Knowledge When Solving Mechanical Problems

    E-Print Network [OSTI]

    Reisz, Z

    2015-01-01

    performance on tests of mechanical comprehension (Masterís10.1002/tea.366031100 Mechanical Self-Efficacy Proceduralcomposition of Note. MSE = mechanical self-efficacy, KS =

  11. Philosophy of Mind and the Problem of Free Will in the Light of Quantum Mechanics.

    E-Print Network [OSTI]

    Stapp, Henry P

    2008-01-01

    Foundations of Quantum Mechanics. (Princeton UniversityMind, Matter, and Quantum Mechanics, (Springer, Berlin & NewMindful Universe: Quantum Mechanics and the Participating

  12. Statistical mechanics problem sheet 1 Unstarred problems follow quickly from definitions and equations in the lectures; single

    E-Print Network [OSTI]

    Dettmann, Carl

    and equations in the lectures; single starred problems require more effort; double starred questions as isolated, closed or open, and give a brief expla- nation of your answer: (a) The solar system (b) A tin) The average energy of a molecule. (c) The maximum energy of a molecule. (d) The logarithm of the number

  13. Problem

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration wouldMass mapSpeedingProgramExemptions | National NuclearProbingProbing metal2 Problem Scarcity

  14. A solution of the measurement problem in quantum mechanics by using a variable hidden in Newtonian mechanics

    E-Print Network [OSTI]

    Jae-Hyung Myung

    2012-03-29

    The problem of a correct description of the physical phenomena of the Heisenberg uncertainty relation is solved by using a variable hidden in Newtonian mehcanics.

  15. Generalization of Abel's mechanical problem: The extended isochronicity condition and the superposition principle

    SciTech Connect (OSTI)

    Kinugawa, Tohru, E-mail: kinugawa@phoenix.kobe-u.ac.jp [Institute for Promotion of Higher Education, Kobe University, Kobe 657-8501 (Japan)] [Institute for Promotion of Higher Education, Kobe University, Kobe 657-8501 (Japan)

    2014-02-15

    This paper presents a simple but nontrivial generalization of Abel's mechanical problem, based on the extended isochronicity condition and the superposition principle. There are two primary aims. The first one is to reveal the linear relation between the transit-time T and the travel-length X hidden behind the isochronicity problem that is usually discussed in terms of the nonlinear equation of motion (d{sup 2}X)/(dt{sup 2}) +(dU)/(dX) =0 with U(X) being an unknown potential. Second, the isochronicity condition is extended for the possible Abel-transform approach to designing the isochronous trajectories of charged particles in spectrometers and/or accelerators for time-resolving experiments. Our approach is based on the integral formula for the oscillatory motion by Landau and Lifshitz [Mechanics (Pergamon, Oxford, 1976), pp. 27Ė29]. The same formula is used to treat the non-periodic motion that is driven by U(X). Specifically, this unknown potential is determined by the (linear) Abel transform X(U)???A[T(E)], where X(U) is the inverse function of U(X), A=(1/?(?))?{sub 0}{sup E}dU/?(E?U) is the so-called Abel operator, and T(E) is the prescribed transit-time for a particle with energy E to spend in the region of interest. Based on this Abel-transform approach, we have introduced the extended isochronicity condition: typically, ? = T{sub A}(E) + T{sub N}(E) where ? is a constant period, T{sub A}(E) is the transit-time in the Abel type [A-type] region spanning X > 0 and T{sub N}(E) is that in the Non-Abel type [N-type] region covering X < 0. As for the A-type region in X > 0, the unknown inverse function X{sub A}(U) is determined from T{sub A}(E) via the Abel-transform relation X{sub A}(U)???A[T{sub A}(E)]. In contrast, the N-type region in X < 0 does not ensure this linear relation: the region is covered with a predetermined potential U{sub N}(X) of some arbitrary choice, not necessarily obeying the Abel-transform relation. In discussing the isochronicity problem, there has been no attempt of N-type regions that are practically of full use for the charged-particle spectrometers and/or accelerators. In this Abel-transform approach, the superposition principle simplifies the derivation of X{sub A}(U) satisfying the extended isochronicity condition. Although the extended isochronicity condition inevitably discards the low-energy particles, there is no problem for handling accelerated particles because they do not involve the small-amplitude oscillations around the potential minimum. We present analytic examples of X{sub A}(U) that are instructive. In Appendix B, Urabe's criterion is interpreted in the time domain, using the Abel-transform approach.

  16. Repairable chip bonding/interconnect process

    DOE Patents [OSTI]

    Bernhardt, Anthony F. (Berkeley, CA); Contolini, Robert J. (Livermore, CA); Malba, Vincent (Livermore, CA); Riddle, Robert A. (Tracy, CA)

    1997-01-01

    A repairable, chip-to-board interconnect process which addresses cost and testability issues in the multi-chip modules. This process can be carried out using a chip-on-sacrificial-substrate technique, involving laser processing. This process avoids the curing/solvent evolution problems encountered in prior approaches, as well is resolving prior plating problems and the requirements for fillets. For repairable high speed chip-to-board connection, transmission lines can be formed on the sides of the chip from chip bond pads, ending in a gull wing at the bottom of the chip for subsequent solder.

  17. Repairable chip bonding/interconnect process

    DOE Patents [OSTI]

    Bernhardt, A.F.; Contolini, R.J.; Malba, V.; Riddle, R.A.

    1997-08-05

    A repairable, chip-to-board interconnect process which addresses cost and testability issues in the multi-chip modules is disclosed. This process can be carried out using a chip-on-sacrificial-substrate technique, involving laser processing. This process avoids the curing/solvent evolution problems encountered in prior approaches, as well is resolving prior plating problems and the requirements for fillets. For repairable high speed chip-to-board connection, transmission lines can be formed on the sides of the chip from chip bond pads, ending in a gull wing at the bottom of the chip for subsequent solder. 10 figs.

  18. Development of bonded composite doublers for the repair of oil recovery equipment.

    SciTech Connect (OSTI)

    Roach, David W.; Rackow, Kirk A.

    2005-06-01

    An unavoidable by-product of a metallic structure's use is the appearance of crack and corrosion flaws. Economic barriers to the replacement of these structures have created an aging infrastructure and placed even greater demands on efficient and safe repair methods. In the past decade, an advanced composite repair technology has made great strides in commercial aviation use. Extensive testing and analysis, through joint programs between the Sandia Labs FAA Airworthiness Assurance Center and the aviation industry, have proven that composite materials can be used to repair damaged aluminum structure. Successful pilot programs have produced flight performance history to establish the durability of bonded composite patches as a permanent repair on commercial aircraft structures. With this foundation in place, this effort is adapting bonded composite repair technology to civil structures. The use of bonded composite doublers has the potential to correct the difficulties associated with current repair techniques and the ability to be applied where there are no rehabilitation options. It promises to be cost-effective with minimal disruption to the users of the structure. This report concludes a study into the application of composite patches on thick steel structures typically used in mining operations. Extreme fatigue, temperature, erosive, and corrosive environments induce an array of equipment damage. The current weld repair techniques for these structures provide a fatigue life that is inferior to that of the original plate. Subsequent cracking must be revisited on a regular basis. The use of composite doublers, which do not have brittle fracture problems such as those inherent in welds, can help extend the structure's fatigue life and reduce the equipment downtime. Two of the main issues for adapting aircraft composite repairs to civil applications are developing an installation technique for carbon steel and accommodating large repairs on extremely thick structures. This study developed and proved an optimum field installation process using specific mechanical and chemical surface preparation techniques coupled with unique, in-situ heating methods. In addition, a comprehensive performance assessment of composite doubler repairs was completed to establish the viability of this technology for large, steel structures. The factors influencing the durability of composite patches in severe field environments were evaluated along with related laminate design issues.

  19. Reputation mechanism: From resolution for truthful online auctions to the model of optimal one-gambler problem

    SciTech Connect (OSTI)

    Bradonjic, Milan [Los Alamos National Laboratory

    2009-01-01

    In this paper we study reputation mechanisms, and show how the notion of reputation can help us in building truthful online auction mechanisms. From the mechanism design prospective, we derive the conditions on and design a truthful online auction mechanism. Moreover, in the case when some agents may lay or cannot have the real knowledge about the other agents reputations, we derive the resolution of the auction, such that the mechanism is truthful. Consequently, we move forward to the optimal one-gambler/one-seller problem, and explain how that problem is refinement of the previously discussed online auction design in the presence of reputation mechanism. In the setting of the optimal one-gambler problem, we naturally rise and solve the specific question: What is an agent's optimal strategy, in order to maximize his revenue? We would like to stress that our analysis goes beyond the scope, which game theory usually discusses under the notion of reputation. We model one-player games, by introducing a new parameter (reputation), which helps us in predicting the agent's behavior, in real-world situations, such as, behavior of a gambler, real-estate dealer, etc.

  20. Asymptotic Methods for PDE Problems in Fluid Mechanics and Related Systems

    E-Print Network [OSTI]

    Ward, Michael Jeffrey

    Perturbations in Two-Dimensional Domains Michael J. Ward (UBC) CISM Workshop; Asymptotic Methods in Fluid Viscous Flow CISM ≠ p.1 #12;Outline of Lecture II TWO SPECIFIC PROBLEMS CONSIDERED: 1. A Nonlinear Eigenvalue Problem with a Hole 2. Slow Viscous Flow Over a Cylinder CISM ≠ p.2 #12;Nonlinear Elliptic Problem

  1. Asymptotic Methods for PDE Problems in Fluid Mechanics and Related Systems

    E-Print Network [OSTI]

    Ward, Michael Jeffrey

    Perturbations in Two-Dimensional Domains Michael J. Ward (UBC) CISM Advanced Course; Asymptotic Methods in Fluid Problems CISM ≠ p.1 #12;Outline of Lecture I TWO SPECIFIC PROBLEMS CONSIDERED: 1. A Model Pipe Flow Problem() that embeds all of the infinite logarithmic terms V A() + O() , where = -1/ log and k for any k > 0. CISM

  2. Rapid road repair vehicle

    DOE Patents [OSTI]

    Mara, Leo M. (Livermore, CA)

    1999-01-01

    Disclosed are improvments to a rapid road repair vehicle comprising an improved cleaning device arrangement, two dispensing arrays for filling defects more rapidly and efficiently, an array of pre-heaters to heat the road way surface in order to help the repair material better bond to the repaired surface, a means for detecting, measuring, and computing the number, location and volume of each of the detected surface imperfection, and a computer means schema for controlling the operation of the plurality of vehicle subsystems. The improved vehicle is, therefore, better able to perform its intended function of filling surface imperfections while moving over those surfaces at near normal traffic speeds.

  3. Asymptotic Methods for PDE Problems in Fluid Mechanics and Related Systems

    E-Print Network [OSTI]

    Ward, Michael Jeffrey

    Perturbations in Two-Dimensional Domains Michael J. Ward (UBC) CISM Advanced Course; Asymptotic Methods in Fluid CISM ≠ p.1 #12;Outline of Lecture III Singularly Perturbed Eigenvalue Problems in Domains Eigenvalue on the Sphere 3. Narrow Escape From Within a Sphere CISM ≠ p.2 #12;Eigenvalue Problem

  4. Quantum mechanical aspects of friction and electric resistance in microscopic problems with applications to radiation physics

    E-Print Network [OSTI]

    Ulmer, W

    2015-01-01

    Friction incorporates the close connection between classical mechanics in irreversible thermodynamics. The translation to a quantum mechanical foundation is not trivial and requires a generalization of the Lagrange function. A change to electromagnetic circuits appears to more adequate, since the electric analogue (Ohms law) is related to scatter of electrons at lattice vibrations.

  5. Hp-spectral Methods for Structural Mechanics and Fluid Dynamics Problems

    E-Print Network [OSTI]

    Ranjan, Rakesh

    2011-08-08

    , consider the analysis of plates subject to external loadings, and large deformation analysis of beams with continuum based formulations. Higher order methods alleviate the problems of locking that have plagued finite element method applications...

  6. LASER ENGINEERED NET SHAPING FOR REPAIR AND HYDROGEN COMPATIBILITY

    SciTech Connect (OSTI)

    Korinko, P.; Adams, T.

    2011-08-05

    A method to repair mismatched or damaged components using Laser Engineered Net Shaping{sup R} (LENS) technology to apply material was investigated for its feasibility for components exposed to hydrogen. The mechanical properties of LENS bulk materials were also tested for hydrogen compatibility. The LENS process was used to repair simulated and actual mismachined components. These sample components were hydrogen charged and burst tested in the as-received, as-damaged, and as-repaired conditions. The testing showed that there was no apparent additional deficiency associated with hydrogen charging compared to the repair technique. The repair techniques resulted in some components meeting the requirements while others did not. Additional procedure/process development is required prior to recommending production use of LENS.

  7. Staged Program Repair in SPR (Supplementary Material)

    E-Print Network [OSTI]

    Long, Fan

    2015-03-05

    We present SPR, a new program repair system that uses condition synthesis to instantiate transformation schemas to repair program defects. SPR's staged repair strategy combines a rich space of potential repairs with a ...

  8. Window Replacement, Rehabilitation, & Repair Guides - Building...

    Energy Savers [EERE]

    Window Replacement, Rehabilitation, & Repair Guides - Building America Top Innovation Window Replacement, Rehabilitation, & Repair Guides - Building America Top Innovation Effec...

  9. Verification of Motor Repair Quality†

    E-Print Network [OSTI]

    Butler, K.

    1998-01-01

    is done properly. But how can an industrial customer know that the motor has been repaired properly?...

  10. Quantum mechanics on spaces of nonconstant curvature: The oscillator problem and superintegrability

    SciTech Connect (OSTI)

    Ballesteros, Angel, E-mail: angelb@ubu.es [Departamento de Fisica, Universidad de Burgos, 09001 Burgos (Spain); Enciso, Alberto, E-mail: aenciso@fis.ucm.es [Departamento de Fisica Teorica II, Universidad Complutense, 28040 Madrid (Spain); Herranz, Francisco J., E-mail: fjherranz@ubu.es [Departamento de Fisica, Universidad de Burgos, 09001 Burgos (Spain); Ragnisco, Orlando, E-mail: ragnisco@fis.uniroma3.it [Dipartimento di Fisica, Universita di Roma Tre and Istituto Nazionale di Fisica Nucleare sezione di Roma Tre, Via Vasca Navale 84, 00146 Roma (Italy); Riglioni, Danilo, E-mail: riglioni@fis.uniroma3.it [Dipartimento di Fisica, Universita di Roma Tre and Istituto Nazionale di Fisica Nucleare sezione di Roma Tre, Via Vasca Navale 84, 00146 Roma (Italy)

    2011-08-15

    Highlights: > Quantization of Hamiltonians on spaces of nonconstant curvature is addressed. > Our approach is based on superintegrability requirements. > The procedure is applied to a nonlinear classical superintegrable oscillator. > Schroedinger, Laplace-Beltrami and PDM quantizations are worked out. > The quantum system is solved by obtaining the spectrum and the eigenfunctions. - Abstract: The full spectrum and eigenfunctions of the quantum version of a nonlinear oscillator defined on an N-dimensional space with nonconstant curvature are rigorously found. Since the underlying curved space generates a position-dependent kinetic energy, three different quantization prescriptions are worked out by imposing that the maximal superintegrability of the system has to be preserved after quantization. The relationships among these three Schroedinger problems are described in detail through appropriate similarity transformations. These three approaches are used to illustrate different features of the quantization problem on N-dimensional curved spaces or, alternatively, of position-dependent mass quantum Hamiltonians. This quantum oscillator is, to the best of our knowledge, the first example of a maximally superintegrable quantum system on an N-dimensional space with nonconstant curvature.

  11. DNA repair: Dynamic defenders against cancer and aging

    SciTech Connect (OSTI)

    Fuss, Jill O.; Cooper, Priscilla K.

    2006-04-01

    You probably weren't thinking about your body's cellular DNA repair systems the last time you sat on the beach in the bright sunshine. Fortunately, however, while you were subjecting your DNA to the harmful effects of ultraviolet light, your cells were busy repairing the damage. The idea that our genetic material could be damaged by the sun was not appreciated in the early days of molecular biology. When Watson and Crick discovered the structure of DNA in 1953 [1], it was assumed that DNA is fundamentally stable since it carries the blueprint of life. However, over 50 years of research have revealed that our DNA is under constant assault by sunlight, oxygen, radiation, various chemicals, and even our own cellular processes. Cleverly, evolution has provided our cells with a diverse set of tools to repair the damage that Mother Nature causes. DNA repair processes restore the normal nucleotide sequence and DNA structure of the genome after damage [2]. These responses are highly varied and exquisitely regulated. DNA repair mechanisms are traditionally characterized by the type of damage repaired. A large variety of chemical modifications can alter normal DNA bases and either lead to mutations or block transcription if not repaired, and three distinct pathways exist to remove base damage. Base excision repair (BER) corrects DNA base alterations that do not distort the overall structure of the DNA helix such as bases damaged by oxidation resulting from normal cellular metabolism. While BER removes single damaged bases, nucleotide excision repair (NER) removes short segments of nucleotides (called oligonucleotides) containing damaged bases. NER responds to any alteration that distorts the DNA helix and is the mechanism responsible for repairing bulky base damage caused by carcinogenic chemicals such as benzo [a]pyrene (found in cigarette smoke and automobile exhaust) as well as covalent linkages between adjacent pyrimidine bases resulting from the ultraviolet (UV) component of sunlight. NER can be divided into two classes based on where the repair occurs. NER occurring in DNA that is not undergoing transcription (i.e., most of the genome) is called global genome repair (GGR or GGNER), while NER taking place in the transcribed strand of active genes is called transcription-coupled repair (TCR or TC-NER). We will explore NER in more detail below. Mismatch repair (MMR) is another type of excision repair that specifically removes mispaired bases resulting from replication errors. DNA damage can also result in breaks in the DNA backbone, in one or both strands. Single-strand breaks (SSBs) are efficiently repaired by a mechanism that shares common features with the later steps in BER. Double-strand breaks (DSBs) are especially devastating since by definition there is no intact complementary strand to serve as a template for repair, and even one unrepaired DSB can be lethal [3]. In cells that have replicated their DNA prior to cell division, the missing information can be supplied by the duplicate copy, or sister chromatid, and DSBs in these cells are faithfully repaired by homologous recombination involving the exchange of strands of DNA between the two copies. However, most cells in the body are non-dividing, and in these cells the major mechanism for repairing DSBs is by non-homologous end joining (NHEJ), which as the name implies involves joining two broken DNA ends together without a requirement for homologous sequence and which therefore has a high potential for loss of genetic information.

  12. New mechanism of solution of the $kT$-problem in magnetobiology

    E-Print Network [OSTI]

    Zakirjon Kanokov; Juern W. P. Schmelzer; Avazbek K. Nasirov

    2009-09-03

    The effect of ultralow-frequency or static magnetic and electric fields on biological processes is of huge interest for researchers due to the resonant change of the intensity of biochemical reactions although the energy in such fields is small. A simplified model to study the effect of the weak magnetic and electrical fields on fluctuation of the random ionic currents in blood and to solve the $k_BT$ problem in magnetobiology is suggested. The analytic expression for the kinetic energy of the molecules dissolved in certain liquid media is obtained. The values of the magnetic field leading to resonant effects in capillaries are estimated. The numerical estimates showed that the resonant values of the energy of molecular in the capillaries and aorta are different: under identical conditions a molecule of the aorta gets $10^{-9}$ times less energy than the molecules in blood capillaries. So the capillaries are very sensitive to the resonant effect, with an approach to the resonant value of the magnetic field strength, the average energy of the molecule localized in the capillary is increased by several orders of magnitude as compared to its thermal energy, this value of the energy is sufficient for the deterioration of the chemical bonds.

  13. Fracture Mechanics implications for apparent static friction coefficient in contact problems involving slip-weakening laws

    E-Print Network [OSTI]

    A. Papangelo; M. Ciavarella; J. R. Barber

    2015-06-19

    We consider the effect of differing coefficients of static and dynamic friction coefficients on the behaviour of contacts involving microslip. The classic solutions of Cattaneo and Mindlin are unchanged if the transition in coefficients is abrupt, but if it occurs over some small slip distance, the solution has some mathematical similarities with those governing the normal tractions in adhesive contact problems. In particular, if the transition to dynamic slip occurs over a sufficiently small area, we can identify a `JKR' approximation, where the transition region is condensed to a line. A local singularity in shear traction is then predicted, with a stress-intensity factor that is proportional to the the square root of the local contact pressure and to a certain integral of the friction coefficient-slip distance relation. We can also define an equivalent of the `small-scale yielding' criterion, which enables us to assess when the singular solution provides a good approximation. One consequence of the results is that the static coefficient of friction determined from force measurements in experiments is significantly smaller than the value that holds at the microscale.

  14. Presented at the 27th Leeds-Lyon Symposium on Tribology, Tribological Research: From Model Experiment to Industrial Problems: Mechanics, Materials Science, Physico-chemistry Lyon,

    E-Print Network [OSTI]

    √?agin, Tahir

    1 Presented at the 27th Leeds-Lyon Symposium on Tribology, Tribological Research: From Model Experiment to Industrial Problems: Mechanics, Materials Science, Physico-chemistry Lyon, France, September 5

  15. Development/Plasticity/Repair Persistence of Experience-Induced Homeostatic Synaptic

    E-Print Network [OSTI]

    Lee, Hey-Kyoung

    Development/Plasticity/Repair Persistence of Experience-Induced Homeostatic Synaptic Plasticity. Theoretical analyses indicate that there are two synaptic plasticity mechanisms required: input. Experience-dependent homeostatic synaptic plasticity mechanisms have subsequently been demonstrated

  16. Polymer nanocomposites for high-temperature composite repair

    SciTech Connect (OSTI)

    Sheng, Xia

    2008-12-01

    A novel repair agent for resin-injection repair of advanced high temperature composites was developed and characterized. The repair agent was based on bisphenol E cyanate ester (BECy) and reinforced with alumina nanoparticles. To ensure good dispersion and compatibility with the BECy matrix in nanocomposites, the alumina nanoparticles were functionalized with silanes. The BECy nanocomposites, containing bare and functionalized alumina nanoparticles, were prepared and evaluated for their thermal, mechanical, rheological, and viscoelastic properties. The monomer of BECy has an extremely low viscosity at ambient temperature, which is good for processability. The cured BECy polymer is a highly cross-linked network with excellent thermal mechanical properties, with a high glass transition temperature (T{sub g}) of 270 C and decomposition temperature above 350 C. The incorporation of alumina nanoparticles enhances the mechanical and rheological properties of the BECy nanocomposites. Additionally, the alumina nanoparticles are shown to catalyze the cure of BECy. Characterization of the nanocomposites included dynamic mechanical analysis, differential scanning calorimetry, thermogravimetric analysis, rheological and rheokinetic evaluation, and transmission electron microscopy. The experimental results show that the BECy nanocomposite is a good candidate as repair agent for resin-injection repair applications.

  17. Service and Repair Work

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefieldSulfateSciTechtail.Theory ofDidDevelopment Top Scientific Impact SinceService and Repair Work

  18. Motor Repair Tech Brief

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    lubrication for your own operating circumstances. Unusual Mechanical Loads A variety of mechanical conditions can either overstress bearings, leading to early failure, or distort...

  19. Awarded Products Maintenance, Repair & Operations TOOLS & HARDWARE

    E-Print Network [OSTI]

    California at San Diego, University of

    Awarded Products Maintenance, Repair & Operations (MRO): TOOLS & HARDWARE Such as hand and power tools, cutting tools, fasteners, etc. Maintenance, Repair & Operations (MRO): TOOLS & HARDWARE Such as hand and power tools, cutting tools, fasteners, etc. Maintenance, Repair & Operations (MRO): TOOLS

  20. A Self-Repairing Peer-to-Peer System Resilient to Dynamic Adversarial Churn

    E-Print Network [OSTI]

    A Self-Repairing Peer-to-Peer System Resilient to Dynamic Adversarial Churn Fabian Kuhn, Stefan at any time. Such peers join and leave the P2P system at high rates ("churn"), a problem

  1. A Self-Repairing Peer-to-Peer System Resilient to Dynamic Adversarial Churn

    E-Print Network [OSTI]

    A Self-Repairing Peer-to-Peer System Resilient to Dynamic Adversarial Churn Fabian Kuhn, Stefan rates ("churn"), a problem that is not existent in orthodox distributed systems. In other words, a P2P

  2. The Self-Construction and -Repair of a Foraging

    E-Print Network [OSTI]

    Siegelmann , Hava T

    at explicit design of self-constructing and -repairing systems by hierarchical specification of elementary intracellular mechanisms via a kind of genetic code. The interplay between individual cells and the gradually are usually designed and constructed by a process that transforms an explicit, abstract description

  3. Thermosetting Polymer-Matrix Composites for Strucutral Repair Applications

    SciTech Connect (OSTI)

    William Kirby Goertzen

    2007-12-01

    Several classes of thermosetting polymer matrix composites were evaluated for use in structural repair applications. Initial work involved the characterization and evaluation of woven carbon fiber/epoxy matrix composites for structural pipeline repair. Cyanate ester resins were evaluated as a replacement for epoxy in composites for high-temperature pipe repair applications, and as the basis for adhesives for resin infusion repair of high-temperature composite materials. Carbon fiber/cyanate ester matrix composites and fumed silica/cyanate ester nanocomposites were evaluated for their thermal, mechanical, viscoelastic, and rheological properties as they relate to their structure, chemistry, and processing characteristics. The bisphenol E cyanate ester under investigation possesses a high glass transition temperature, excellent mechanical properties, and unique ambient temperature processability. The incorporate of fumed silica served to enhance the mechanical and rheological properties of the polymer and reduce thermal expansion without sacrificing glass transition or drastically altering curing kinetics. Characterization of the composites included dynamic mechanical analysis, thermomechanical analysis, differential scanning calorimetry, thermogravimetric analysis, rheological and rheokinetic evaluation, and transmission electron microscopy.

  4. Using instrument scraper surveys for corrosion repair

    SciTech Connect (OSTI)

    Akhnoukh, S.R.; Baghabrah, M.A. (Aramco (SA))

    1990-07-01

    This paper reports on a program for overall pipe line repair. This program was implemented to maintain pipe line integrity and for identifying problem areas which require reconditioning or replacing by: reviewing pipe line leak history; checking periodically lifetime expectancy and integrity of pipe coatings; using cathodic protection annual survey results to locate low potential areas (close-interval survey is needed to identify the exact location of corrosion); and hydrotesting the pipe line (using leaks or ruptures from the hydrotest to identify problem areas). The pipe line revalidation plan is insufficient for identifying pipe line leaks. Instrumented pig testing provides more accurate and reliable ways of testing the pipe line for internal or external corrosion or defects.

  5. Emerging Trends in Heart Valve Engineering: Part III. Novel Technologies for Mitral Valve Repair and Replacement

    E-Print Network [OSTI]

    2015-01-01

    and J. D. Puskas. Mitral-valve repair versus replacement forbioprosthetic heart valves. Ann. Thorac. Surg. 71:S417Ėmechanics of arti?cial heart valves. Clin. Exp. Pharmacol.

  6. The repair and rehabilitation method of Tokyo gas

    SciTech Connect (OSTI)

    Yagi, Shuichi [Tokyo Gas Co., Ltd. (Japan)

    1996-08-01

    It has been an important matter for gas utilities to maintain their pipelines easily and economically. But pipes that have become old suffer from progressive corrosion, and as a result of vibration caused by traffic or the effects of land subsidence, joints can become loosened. To repair pipes that have suffered in such ways, the usual method to do is to dig them up and replace them with new ones. But this method requires a large amount of excavation, so the work takes a long time to complete and is costly. To deal with these problems, Tokyo Gas developed number of repair and rehabilitation methods to permit renewal of pipelines without replacing them. In this paper, I would like to introduce our repair and rehabilitation methods for low-pressure pipeline. 4 refs., 9 figs., 4 tabs.

  7. Selected Bibliography on Electric Motor Repair | Department of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Selected Bibliography on Electric Motor Repair Selected Bibliography on Electric Motor Repair The following series of repair documents related to electric motors were produced by...

  8. An assessment of least squares finite element models with applications to problems in heat transfer and solid mechanics

    E-Print Network [OSTI]

    Pratt, Brittan Sheldon

    2008-10-10

    form Galerkin. The examples presented for the beam problem include: a cantilever beam with linearly varying distributed load along the beam and a point load at the end, a simply supported beam with a point load in the middle, and a beam fixed on both...

  9. AMEAerospace & Mechanical

    E-Print Network [OSTI]

    Wang, Hai

    , emerging fuel cell technolo- gies, computational fluid mechanics, ground vehicle aerodynamics, combustion students develop problem solving skills in the areas of mechanics, thermody- namics, fluid mechanics, heat advance our understanding of such areas as continuum and particulate fluid mechanics, flight mechanics

  10. A solution of the strong CP problem via the Peccei-Quinn mechanism through the Nieh-Yan modified gravity and cosmological implications

    E-Print Network [OSTI]

    Massimiliano Lattanzi; Simone Mercuri

    2010-06-23

    By identifying the recently introduced Barbero-Immirzi field with the QCD axion, the strong CP problem can be solved through the Peccei-Quinn mechanism. A specific energy scale for the Peccei-Quinn symmetry breaking is naturally predicted by this model. This provides a complete dynamical setting to evaluate the contribution of such an axion to the cold dark matter content of the Universe. Furthermore, a tight upper bound on the tensor-to-scalar ratio production of primordial gravitational waves can be fixed, representing a strong experimental test for this model.

  11. IN OTHER CATEGORIES; MACHINERY; MASS BALANCE; MECHANICAL VIBRATIONS...

    Office of Scientific and Technical Information (OSTI)

    world Bracher, B. 42 ENGINEERING NOT INCLUDED IN OTHER CATEGORIES; MACHINERY; MASS BALANCE; MECHANICAL VIBRATIONS; MAINTENANCE; REPAIR Field balancing can achieve significant...

  12. A novel role for the transcriptional modulator NusA in DNA repair/damage tolerance pathways in Escherichia coli

    E-Print Network [OSTI]

    Cohen, Susan E., Ph. D. Massachusetts Institute of Technology

    2009-01-01

    All organisms must contend with the consequences of DNA damage, induced by a variety of both endogenous and exogenous sources. Mechanisms of DNA repair and DNA damage tolerance are crucial for cellular survival after DNA ...

  13. The biomechanics of cruciate ligament repair

    E-Print Network [OSTI]

    Ferry, Katheryn Irene

    2013-02-22

    -1 THE BIOMECHAIVICS OF CR UCIA TE LIGAMEJV T REPAIR A Senior Thesis By Katheryn Irene Ferry 1997-98 University Undergraduate Research Fellow Texas A&M University Group: Engineering II THE BIOMECHANICS OF CRUCIATE LIGAMENT REPAIR by KATHRYN IRENE FERRY... by the The Biomechanics of Cruciate Ligament Repair femorotibial ligaments which include the collateral ligaments, the cranial cruciate ligament, and the caudal cruciate ligament (Vasseur, 1993). The anatomy and spatial arrangement of the femorotibial ligaments...

  14. Chemical Fume Hood Maintenance, Repair and Certification

    E-Print Network [OSTI]

    Jia, Songtao

    in the lab. Removes lockout of hoods, if used. g. Notify EH&S to perform re-certification after repair

  15. How to repair a leaking faucet The problem

    E-Print Network [OSTI]

    s Llaves que gotean desperdician agua. s Llaves que gotean pueden causar una mancha en el fregadero. s Un sabe el diŠmetro exacto) s Un desarmador s Una llave ajustable Cůmo hacerlo 1. Primero, corte el agua de salir el agua (Fig. 1). 2. Afloje la tuerca de compresiůn con la llave ajustable (Fig. 2). (La

  16. Electric plugs--repair or replace The problem

    E-Print Network [OSTI]

    need s New plug≠if your old one cannot be used. (Buy one with a UL label) s A screwdriver s A knife How to 1. Cut the cord off at the damaged part (Fig. 1). 2. Slip the plug back on the cord (Fig. 2). 3

  17. Role of DNA repair protein ERCC1 in skin cancer†

    E-Print Network [OSTI]

    Song, Liang

    2009-01-01

    Nucleotide excision repair (NER) is one of the major repair systems for removal of DNA lesions. The NER pathway has evolved mainly to repair UV-induced DNA damage and is also active against a broad range of endogenously ...

  18. Internal pipe attachment mechanism

    DOE Patents [OSTI]

    Bast, R.M.; Chesnut, D.A.; Henning, C.D.; Lennon, J.P.; Pastrnak, J.W.; Smith, J.A.

    1994-12-13

    An attachment mechanism is described for repairing or extending fluid carrying pipes, casings, conduits, etc. utilizing one-way motion of spring tempered fingers to provide a mechanical connection between the attachment mechanism and the pipe. The spring tempered fingers flex to permit insertion into a pipe to a desired insertion depth. The mechanical connection is accomplished by reversing the insertion motion and the mechanical leverage in the fingers forces them outwardly against the inner wall of the pipe. A seal is generated by crushing a sealing assembly by the action of setting the mechanical connection. 6 figures.

  19. Leveraging Service Calls and Emergency Repairs for Energy Efficiency...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Service Calls and Emergency Repairs for Energy Efficiency Marketing Leveraging Service Calls and Emergency Repairs for Energy Efficiency Marketing Better Buildings Residential...

  20. Solar Water Heating System Maintenance and Repair | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Solar Water Heating System Maintenance and Repair Solar Water Heating System Maintenance and Repair May 30, 2012 - 2:35pm Addthis Rooftop solar water heaters need regular...

  1. From Validation to Automated Repair & Beyond with Constraint Solving

    E-Print Network [OSTI]

    Samimi, Hesam

    2013-01-01

    HTML GenerationRepair: Automated Repair of HTML Generation Errors in PHPrenderings of our invalid HTML page in Google Chrome 13.0 (

  2. INTERNAL REPAIR OF PIPELINES REVIEW & EVALUATION OF INTERNAL PIPELINE REPAIR TRIALS REPORT

    SciTech Connect (OSTI)

    Robin Gordon; Bill Bruce; Ian Harris; Dennis Harwig; George Ritter; Bill Mohr; Matt Boring; Nancy Porter; Mike Sullivan; Chris Neary

    2004-09-01

    The two broad categories of fiber-reinforced composite liner repair and deposited weld metal repair technologies were reviewed and evaluated for potential application for internal repair of gas transmission pipelines. Both are used to some extent for other applications and could be further developed for internal, local, structural repair of gas transmission pipelines. Evaluation trials were conducted on pipe sections with simulated corrosion damage repaired with glass fiber-reinforced composite liners, carbon fiber-reinforced composite liners, and weld deposition. Additional un-repaired pipe sections were evaluated in the virgin condition and with simulated damage. Hydrostatic failure pressures for pipe sections repaired with glass fiber-reinforced composite liner were only marginally greater than that of pipe sections without liners, indicating that this type of liner is generally ineffective at restoring the pressure containing capabilities of pipelines. Failure pressure for pipe repaired with carbon fiber-reinforced composite liner was greater than that of the un-repaired pipe section with damage, indicating that this type of liner is effective at restoring the pressure containing capability of pipe. Pipe repaired with weld deposition failed at pressures lower than that of un-repaired pipe in both the virgin and damaged conditions, indicating that this repair technology is less effective at restoring the pressure containing capability of pipe than a carbon fiber-reinforced liner repair. Physical testing indicates that carbon fiber-reinforced liner repair is the most promising technology evaluated to-date. Development of a comprehensive test plan for this process is recommended for use in the next phase of this project.

  3. Mechanical & Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical & Aerospace Engineering Ductile failure in structural materials has been a problem the Temple Foundation Professorship in the Department of Aerospace Engineering and Engineering Mechanics, multiscale experimental mechanics, mechanics of polymers. He is a fellow of the American Society

  4. Fast Interactive Simulations of Mitral Valve Repair Neil A. Tenenholtz, Peter E. Hammer, Robert D. Howe

    E-Print Network [OSTI]

    Fast Interactive Simulations of Mitral Valve Repair Neil A. Tenenholtz, Peter E. Hammer, Robert D. Howe Keywords: Surgical simulation, human-computer interaction, haptics, mitral valve, cardiac surgery. I. Problem Solved A healthy mitral valve ensures the one-way flow of oxygenated blood from the left

  5. Developments advance subsea pipelaying, inspection, repair

    SciTech Connect (OSTI)

    1997-09-15

    Recent advances in laying, inspecting, and repairing pipelines are helping to cut both costs and time. A new dredging system that employs jets to clear a subsea trench for pipelay received trials off Belgium last spring. Also, within the last year, projects in the Middle East and North Sea employed technologies that promise to make inspecting the surface of a subsea pipeline in difficult terrain easier, less time consuming, and therefore less costly. Plus, subsea repair of damaged pipelines may take less time with a new ``stabbable`` pipe connector. The paper describes jet dredging, inspection advance, support software, the North Sea site, and pipeline repair.

  6. Mechanical Engineering ME 3720 FLUID MECHANICS

    E-Print Network [OSTI]

    Panchagnula, Mahesh

    Mechanical Engineering ME 3720 FLUID MECHANICS Pre-requisite: ME 2330 Co-requisite: ME 3210) to develop an understanding of the physical mechanisms and the mathematical models of fluid mechanics of fluid mechanics problems in engineering practice. The basic principles of fluid mechanics

  7. DNA repair efficiency in germ cells and early mouse embryos and consequences for radiation-induced transgenerational genomic damage

    SciTech Connect (OSTI)

    Marchetti, Francesco; Wyrobek, Andrew J.

    2009-01-18

    Exposure to ionizing radiation and other environmental agents can affect the genomic integrity of germ cells and induce adverse health effects in the progeny. Efficient DNA repair during gametogenesis and the early embryonic cycles after fertilization is critical for preventing transmission of DNA damage to the progeny and relies on maternal factors stored in the egg before fertilization. The ability of the maternal repair machinery to repair DNA damage in both parental genomes in the fertilizing egg is especially crucial for the fertilizing male genome that has not experienced a DNA repair-competent cellular environment for several weeks prior to fertilization. During the DNA repair-deficient period of spermatogenesis, DNA lesions may accumulate in sperm and be carried into the egg where, if not properly repaired, could result in the formation of heritable chromosomal aberrations or mutations and associated birth defects. Studies with female mice deficient in specific DNA repair genes have shown that: (i) cell cycle checkpoints are activated in the fertilized egg by DNA damage carried by the sperm; and (ii) the maternal genotype plays a major role in determining the efficiency of repairing genomic lesions in the fertilizing sperm and directly affect the risk for abnormal reproductive outcomes. There is also growing evidence that implicates DNA damage carried by the fertilizing gamete as a mediator of postfertilization processes that contribute to genomic instability in subsequent generations. Transgenerational genomic instability most likely involves epigenetic mechanisms or error-prone DNA repair processes in the early embryo. Maternal and embryonic DNA repair processes during the early phases of mammalian embryonic development can have far reaching consequences for the genomic integrity and health of subsequent generations.

  8. Development/Plasticity/Repair STAT1 Regulates the Homeostatic Component of Visual

    E-Print Network [OSTI]

    Sur, Mriganka

    Development/Plasticity/Repair STAT1 Regulates the Homeostatic Component of Visual Cortical Plasticity via an AMPA Receptor-Mediated Mechanism Ikue Nagakura, Audra Van Wart, Jeremy Petravicz, Daniela signaling in neuronal function; however, its role in experience-dependent plasticity is unknown. Here we

  9. The Stumbling Block in Lung Repair of Emphysema: Elastic Fiber Assembly

    E-Print Network [OSTI]

    Mecham, Robert

    The Stumbling Block in Lung Repair of Emphysema: Elastic Fiber Assembly Adrian Shifren and Robert P properties of the lung are largely determined by the connective tissue networks laid down during development. The macromolecules most important for lung mechanics and structural integrity are collagen, elastin

  10. Reducing Your Leak Rate Without Repairing Leaks†

    E-Print Network [OSTI]

    Beals, C.

    2005-01-01

    below the header pressure have the added advantage of reducing the air consumption of equipment, as well as reducing the leak rate. Turn Off the Air to Idle Equipment In most plants, when production equipment operators shut off their equipment... of the reason why plant personnel often find leak repair unproductive. The other reason relates to the compressor controls. If the plant had several lubricated rotary screw compressors operating in modulation, repairing 2,000 cfm in leaks may only reduce...

  11. INTERNAL REPAIR OF GAS PIPLINES SURVEY OF OPERATOR EXPERIENCE AND INDUSTRY NEEDS REPORT

    SciTech Connect (OSTI)

    Ian D. Harris

    2003-09-01

    A repair method that can be applied from the inside of a gas transmission pipeline (i.e., a trenchless repair) is an attractive alternative to conventional repair methods since the need to excavate the pipeline is precluded. This is particularly true for pipelines in environmentally sensitive and highly populated areas. The objectives of the project are to evaluate, develop, demonstrate, and validate internal repair methods for pipelines; develop a functional specification for an internal pipeline repair system; and prepare a recommended practice for internal repair of pipelines. The purpose of this survey is to better understand the needs and performance requirements of the natural gas transmission industry regarding internal repair. A total of fifty-six surveys were sent to pipeline operators. A total of twenty completed surveys were returned, representing a 36% response rate, which is considered very good given the fact that tailored surveys are known in the marketing industry to seldom attract more than a 10% response rate. The twenty survey responses produced the following principal conclusions: (1) Use of internal weld repair is most attractive for river crossings, under other bodies of water (e.g., lakes and swamps) in difficult soil conditions, under highways, under congested intersections, and under railway crossings. All these areas tend to be very difficult and very costly if, and where, conventional excavated repairs may be currently used. (2) Internal pipe repair offers a strong potential advantage to the high cost of horizontal direct drilling (HDD) when a new bore must be created to solve a leak or other problem in a water/river crossing. (3) The typical travel distances required can be divided into three distinct groups: up to 305 m (1,000 ft.); between 305 m and 610 m (1,000 ft. and 2,000 ft.); and beyond 914 m (3,000 ft.). In concept, these groups require pig-based systems; despooled umbilical systems could be considered for the first two groups. For the last group a self-propelled system with an onboard self-contained power and welding system is required. (4) Pipe size range requirements range from 50.8 mm (2 in.) through 1,219.2 mm (48 in.) in diameter. The most common size range for 80% to 90% of operators surveyed is 508 mm to 762 mm (20 in. to 30 in.) diameter, with 95% using 558.8 mm (22 in.) diameter pipe.

  12. Physics 106a/196a Problem Set 1 Due Oct 7, 2005 These problems cover the material on Newtonian mechanics and gravitation in Sections 1.1 and 1.2

    E-Print Network [OSTI]

    Golwala, Sunil

    and the tensions in the two ropes. Problem 1 Problem 2 2. (106) A block of mass m subject to gravity is dropped that the spring will be compressed using energy methods. (See diagram for definition of h.) 3. (106/196) Two) The earth has approximately the shape of an oblate ellipsoid of revolution whose polar diameter 2 a (1

  13. H A&S 222d/253e: Introduction to Energy and Environment (Life Under the Pale Sun) Problem Set 1: Out: Weds. 11 April 2006 Mechanical and thermal energy

    E-Print Network [OSTI]

    H A&S 222d/253e: Introduction to Energy and Environment (Life Under the Pale Sun) Spring 07 Problem Set 1: Out: Weds. 11 April 2006 Mechanical and thermal energy Back: Weds. 18 April 1. The total `marketable'energy use in the world is estimated as 4 x 1020 Joules/year. In class we converted this to watts

  14. HANFORD SITE LOW EXPOSURE PIPELINE REPAIR USING A NON-METALLIC COMPOSITE SYSTEM

    SciTech Connect (OSTI)

    HUTH RJ

    2009-11-12

    At the Department of Energy, Richland Operations (DOE-RL) Hanford site in eastern Washington, a 350 mm (14 inch) diameter high density polyethylene (HDPE) pump recirculation pipeline failed at a bonded joint adjacent to a radiologically and chemically contaminated groundwater storage basin. The responsible DOE-RL contractor, CH2MHill Plateau Remediation Company, applied a fiberglass reinforced plastic (composite) field repair system to the failed joint. The system was devised specifically for the HDPE pipe repair at the Hanford site, and had not been used on this type of plastic piping previously. This paper introduces the pipe failure scenario, describes the options considered for repair and discusses the ultimate resolution of the problem. The failed pipeline was successfully returned to service with minimal impact on waste water treatment plant operating capacity. Additionally, radiological and chemical exposures to facility personnel were maintained as low as reasonably achievable (ALARA). The repair is considered a success for the near term, and future monitoring will prove whether the repair can be considered for long term service and as a viable alternative for similar piping failures at the Hanford site.

  15. Mechanical instability is usually a problem that engineers try to prevent. Such instabilities can often lead to structural failures and collapses. For example, in engineering, buckling

    E-Print Network [OSTI]

    lithography, stretchable ZnO energy harvester, to Si-anode-based lithium ion battery. Mechanical Engineering

  16. Mechanisms of initiation of DNA mismatch repair in Saccharomyces cerevisiae

    E-Print Network [OSTI]

    Shell, Scarlet Sara

    2008-01-01

    or the cisplatin-d(GpG) adduct. Proc Natl Acad Sci U S A 93,or the cisplatin-d(GpG) adduct. Proc Natl Acad Sci U S A 93,or the cisplatin-d(GpG) adduct. Proc Natl Acad Sci U S A 93,

  17. HYDROGEN EFFECTS ON LASER ENGINEERED NET SHAPE (LENS) REPAIRED WELDMENTS

    SciTech Connect (OSTI)

    Korinko, P; Thad Adams, T

    2006-10-06

    New methods of repairing mis-machined components are always of interest. In this study, an innovative method using Laser Engineered Net Shape{trademark} (LENS{reg_sign}) forming was used to repair intentionally mis-machined test articles. The components were repaired and subsequently hydrogen charged and burst tested. The LENS repair did not have an adverse effect on the solid state weld process that was used to repair the components. Hydrogen charged samples failed in a similar manner to the uncharged samples. Overall, the prospects for LENS repairing similar products are favorable and further work is encouraged.

  18. Development of a composite repair system for reinforcing offshore risers†

    E-Print Network [OSTI]

    Alexander, Christopher Richard

    2009-05-15

    A research program was conducted to investigate the application of composite materials in repairing corroded offshore risers, leading to the development of an optimized repair using a hybrid carbon/E-glass system. The objective of this research...

  19. Solar Water Heating System Maintenance and Repair | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Water Heating System Maintenance and Repair Solar Water Heating System Maintenance and Repair May 30, 2012 - 2:35pm Addthis Rooftop solar water heaters need regular maintenance to...

  20. Repairable File and Storage Systems A Dissertation Presented

    E-Print Network [OSTI]

    Chiueh, Tzi-cker

    Repairable File and Storage Systems A Dissertation Presented by Ningning Zhu to The Graduate School of the Dissertation Repairable File and Storage System by Ningning Zhu Doctor of Philosophy in Computer Science Stony stream file/storage system. Repairable file/storage system needs to perform two tasks. First it has

  1. Asymptotic Interference Alignment for Exact Repair in Distributed Storage Systems

    E-Print Network [OSTI]

    Jafar, Syed A.

    Asymptotic Interference Alignment for Exact Repair in Distributed Storage Systems Viveck R. Cadambe consider a distributed storage system where a file of size M is stored in n distributed storage nodes using of this paper is to repair failed nodes in the storage system, by replacing them by their replicas (exact repair

  2. Emergency pipe line repair connects subsea pipe lines

    SciTech Connect (OSTI)

    Lerique, M.P.; Thiberge, P. ); Wright, N. )

    1990-11-01

    Emergency repair of any subsea line pipe must form a high-integrity, metal-to-metal seal. This paper presents a remote, diverless repair system that utilizes master flanges, a connector and a spool piece to repair line pipe in deep offshore waters.

  3. Level of Repair Analysis and Minimum Cost Homomorphisms of Graphs

    E-Print Network [OSTI]

    Gutin, Gregory

    of Lillian Barros Abstract. Level of Repair Analysis (LORA) is a prescribed procedure for defence logistics, LORA seeks to determine an optimal provision of repair and maintenance facilities to minimize overall on bipartite graphs is polynomial time solvable. Keywords: Computational Logistics; Level of Repair Analysis

  4. EPA Lead Safety for Renovation, Repair and

    E-Print Network [OSTI]

    Tennessee, University of

    EPA Lead Safety for Renovation, Repair and Painting (RRP) Course Certified Renovators Class, CSP, CHMM, Certified Lead Paint Inspector.; Certified Renovator; EPA Ac- credited Lead RRP trainer or fax registratio Registration Form Cash Method of Payment Check Name Mailing Address Phone Lead Safety

  5. Visualization of Mismatch Repair in Bacterial Cells

    E-Print Network [OSTI]

    Smith, Bradley T.

    We determined the localizations of mismatch repair proteins in living Bacillus subtilis cells. MutS-GFP colocalized with the chromosome in all cells and formed foci in a subset of cells. MutL-GFP formed foci in a subset ...

  6. Open Problems, Solved Problems !

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration wouldMass mapSpeeding access toOctober 1996Technologies /June 2011June 2015 runtimeProblems,

  7. New Technologies for Repairing Aging Cables in Nuclear Power Plants

    SciTech Connect (OSTI)

    Simmons, Kevin L. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Fifield, Leonard S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Westman, Matthew P. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2013-09-11

    The goal of this project is to demonstrate a proof-of-concept for a technique to repair aging cables that have been subjected to degradation associated with long-term thermal and radiation exposure in nuclear power plants. The physical degradation of the aging cables manifests itself primarily as cracking and increased brittleness of the polymeric electrical insulation. Therefore, the proposed cable-repair concept comprises development of techniques to impart a softening agent within the deteriorated polymer insulation jacket so as to regain the ability of the insulation to stretch without failing and possibly to heal existing cracks in the insulation. Our approach is to use commercially available ethylene-propylene rubber (EPR) as the relevant test material, demonstrate the adsorption of chemical treatments in the EPR and quantify changes in resulting physical and mechanical properties. EPR cable samples have been thermally treated in air to produce specimens corresponding to the full range of cable age-performance points from new (>350% elongation at break) to end-of-life (<50% elongation at break). The current focus is on two chemical treatments selected as candidates for restoring age-related cable elasticity loss: a rubber plasticizer and a reactive silane molecule. EPR specimens of 200, 150, 100, and 50% elongation at break have been soaked in the candidate chemical treatments and the kinetics of chemical uptake, measured by change in mass of the samples, has been determined. Mechanical properties as a function of aging and chemical treatment have been measured including ultimate tensile strength, tensile modulus at 50% strain, elongation at break, and storage modulus. Dimensional changes with treatment and changes in glass transition temperature were also investigated. These ongoing experiments are expected to provide insight into the physical-chemical nature of the effect of thermal degradation on EPR rejuvenation limits and to advance novel methods for restoring the ability of degraded EPR to be compliant and resist fracture. The results of this research reveal that absorption of chemical treatments can lower the glass transition temperature and modulus of EPR. Chemical treatments pursued thus far have proven ineffective at restoring EPR strength and elongation at break. Future work will combine the plasticizer modalities found to successfully increase the volume of the EPR, reduce EPR glass transition temperature and reduce EPR modulus with promising chemistries that will repair the damage of the polymer, potentially using the plasticizer as a host for the new chemistry.

  8. AdS/CFT Problem Set 1, Due 9-25 1. What is a Duality? Consider these two apparently different quantum mechanical systems

    E-Print Network [OSTI]

    Weaver, Harold A. "Hal"

    AdS/CFT Problem Set 1, Due 9-25 1. What is a Duality? Consider these two apparently different, and how it applies in a QFT context. 3. Flat Space Limit of AdS Isometries. In global coordinates, show that if we expand the AdS metric to leading order in near = 0, we just have the flat space metric. In what

  9. Repair of ultraviolet-light-induced damage

    SciTech Connect (OSTI)

    Sutherland, B.M.

    1981-01-01

    Studies are reviewed which present three major new findings in the photobiology of skin. First, detectable numbers of dimers are formed even at sub-erythymal doses. Second, excision of dimers is much more rapid than would be predicted from results obtained in cell culture. Third, comparison of the rates of excision and photoreactivation in skin indicates that in normal sunlight exposure, photoreactivation may well be the predominant repair pathway in skin. (ACR)

  10. Detection and Repair of Ionizing Radiation-Induced DNA Double Strand Breaks: New Developments in Nonhomologous End Joining

    SciTech Connect (OSTI)

    Wang, Chen [Departments of Biochemistry and Molecular Biology and Oncology, and Southern Alberta Cancer Research Institute, University of Calgary, Calgary (Canada)] [Departments of Biochemistry and Molecular Biology and Oncology, and Southern Alberta Cancer Research Institute, University of Calgary, Calgary (Canada); Lees-Miller, Susan P., E-mail: leesmill@ucalgary.ca [Departments of Biochemistry and Molecular Biology and Oncology, and Southern Alberta Cancer Research Institute, University of Calgary, Calgary (Canada)

    2013-07-01

    DNA damage can occur as a result of endogenous metabolic reactions and replication stress or from exogenous sources such as radiation therapy and chemotherapy. DNA double strand breaks are the most cytotoxic form of DNA damage, and defects in their repair can result in genome instability, a hallmark of cancer. The major pathway for the repair of ionizing radiation-induced DSBs in human cells is nonhomologous end joining. Here we review recent advances on the mechanism of nonhomologous end joining, as well as new findings on its component proteins and regulation.

  11. SNL Researchers Assess Wind Turbine Blade Inspection and Repair...

    Broader source: Energy.gov (indexed) [DOE]

    also inform how blade inspections are conducted at manufacturing facilities and wind farms, thereby improving maintenance and repair procedures for wind turbine blades. SNL is...

  12. Solar Cells, Wound Repair Winning GVC Technologies | ornl.gov

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Solar Cells, Wound Repair Winning GVC Technologies March 26, 2010 Graduate student teams from the University of Arkansas and the University of Maryland earned first place in the...

  13. Protein Bridges DNA Base and Nucleotide Excision Repair Pathways

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Bridges DNA Base and Nucleotide Excision Repair Pathways Print Alkyltransferase proteins (AGT) protect cells from the biological effects of DNA damage caused by the addition...

  14. Model Repair Specifications for Low Voltage Induction Motors

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    EASA AR100-1998 Recommended Practice For The Repair of Rotating Electrical Apparatus IEEE IEEE Std. 43, Recommended Practice for Testing Insulation Resistance of Rotating...

  15. STATISTICAL MECHANICS AND FIELD THEORY

    E-Print Network [OSTI]

    Samuel, S.A.

    2010-01-01

    1. L. 1. Schiff, Quantum Mechanics, third edition (McGraw-two-dimensional quantum mechanics problem vith a potential,Theory Methods to Statistical Mechanics Chapter I The Use of

  16. Investigating the Role of Vitamin D and DNA Repair in Influencing Cancer Presentation and Outcomes†

    E-Print Network [OSTI]

    Syed, Moinuddin Mohammed

    2014-09-26

    differences in DNA repair genes exist, which may in turn contribute to underlying differences in DNA repair capacity. These genes with high Fst value represent all six known common DNA repair pathways and DDR response. This supports our hypothesis...

  17. Waste minimization in an autobody repair shop

    SciTech Connect (OSTI)

    Baria, D.N.; Dorland, D.; Bergeron, J.T.

    1994-12-31

    This work was done to document the waste minimization incorporated in a new autobody repair facility in Hermantown, Minnesota. Humes Collision Center incorporated new waste reduction techniques when it expanded its old facilities in 1992 and it was able to achieve the benefits of cost reduction and waste reduction. Humes Collision Center repairs an average of 500 cars annually and is a very small quantity generator (VSQG) of hazardous waste, as defined by the Minnesota Pollution Control Agency (MPCA). The hazardous waste consists of antifreeze, batteries, paint sludge, refrigerants, and used oil, while the nonhazardous waste consists of cardboard, glass, paint filters, plastic, sanding dust, scrap metal, and wastewater. The hazardous and nonhazardous waste output were decreased by 72%. In addition, there was a 63% reduction in the operating costs. The waste minimization includes antifreeze recovery and recycling, reduction in unused waste paint, reduction, recovery and recycle of waste lacquer thinner for cleaning spray guns and paint cups, elimination of used plastic car bags, recovery and recycle of refrigerant, reduction in waste sandpaper and elimination of sanding dust, and elimination of waste paint filters. The rate of return on the investment in waste minimization equipment is estimated from 37% per year for the distillation unit, 80% for vacuum sanding, 146% for computerized paint mixing, 211% for the refrigerant recycler, to 588% per year for the gun washer. The corresponding payback time varies from 3 years to 2 months.

  18. Effective Metaroutines for Organizational Problem Solving EFFECTIVE METAROUTINES FOR ORGANIZATIONAL PROBLEM SOLVING

    E-Print Network [OSTI]

    Sobek II, Durward K.

    Effective Metaroutines for Organizational Problem Solving 1 EFFECTIVE METAROUTINES FOR ORGANIZATIONAL PROBLEM SOLVING MANIMAY GHOSH and DURWARD K. SOBEK II* Mechanical and Industrial Engineering@ie.montana.edu * Corresponding Author #12;Effective Metaroutines for Organizational Problem Solving 2 Abstract Short

  19. Computational model of aortic valve surgical repair using grafted pericardium

    E-Print Network [OSTI]

    1 Computational model of aortic valve surgical repair using grafted pericardium Peter E. Hammer1, aortic valve repair, membrane, surgical planning, leaflet graft, pericardium ABSTRACT Aortic valve leaflets. Difficulty is largely due to the complex geometry and function of the valve and the lower

  20. Injury and Repair: Retinal Remodeling Robert E. Marc

    E-Print Network [OSTI]

    Marc, Robert E.

    Injury and Repair: Retinal Remodeling Robert E. Marc Department of Ophthalmology John A. Moran Eye Center 65 Mario Capecchi Dr University of Utah Salt Lake City, UT 84132 robert.marc@hsc.utah.edu Keywords photoreceptors In press Elsevier Encyclopedia of the Eye Robert E. Marc :: Chapter 220 :: Injury and Repair

  1. Coherent testing and simulation of composite blade repair

    E-Print Network [OSTI]

    McNichols, Brian Glenn

    1997-01-01

    The objective of this research program is to experimentally and computationally determine the static and fatigue response for two methods of repair to an E/Glass-Epoxy sandwich laminate. The proposed methods of repair are a scarf and overlap patch...

  2. Simplification and Repair of Polygonal Models Using Volumetric Techniques

    E-Print Network [OSTI]

    Turk, Greg

    data sets. Medical sensing technology such as MRI, CT, and PET scanners produce large volume data sets that are nonmanifold and simplification of models. Repair is the process of taking a model that may have undesirable representation that yields a simple yet effective solution to polygon repair. The same voxelization process

  3. Regulation of endometrial repair and its impact on heavy menstrual bleeding†

    E-Print Network [OSTI]

    Maybin, Jacqueline Ann

    2011-11-25

    Introduction: The human endometrium has a remarkable capacity for efficient cyclical repair following the inflammatory process of menstruation. Defective postmenstrual repair may contribute to the common complaint of ...

  4. INDEX POLICIES FOR DISCOUNTED BANDIT PROBLEMS WITH AVAILABILITY CONSTRAINTS

    E-Print Network [OSTI]

    Dayanik, Savas

    down and repair is an option at some cost, and we derive the corresponding Whittle index policy. WeINDEX POLICIES FOR DISCOUNTED BANDIT PROBLEMS WITH AVAILABILITY CONSTRAINTS SAVAS DAYANIK, WARREN the non-existence of an optimal index policy and propose the so-called Whittle index policy after

  5. Mechanisms of cellular transformation by carcinogenic agents

    SciTech Connect (OSTI)

    Grunberger, D.; Goff, S.P.

    1987-01-01

    This book contains 14 chapters. Some of the chapter titles are: DNA Modification by Chemical Carcinogens; Role of DNA Lesions and Repair in the Transformation of Human Cells; The Induction and Regulation of Radiogenic Transformation In Vitro: Cellular and Molecular Mechanisms; Cellular Transformation by Adenoviruses; and The fos Gene.

  6. Funny Problems!

    E-Print Network [OSTI]

    Florentin Smarandache

    2000-10-13

    Thirty original and collected problems, puzzles, and paradoxes in mathematics and physics are explained in this paper, taught by the author to the elementary and high school teachers at the University of New Mexico - Gallup in 1997-8 and afterwards. They have more an educational interest, because make the students think different! For each "solution" a funny logic is invented in order to give the problem a sense.

  7. Best Management Practices (BMPs) for the Ship and Boat Building and Repair

    E-Print Network [OSTI]

    .................................................................................................................. 1 1.3 PROFILE OF THE B.C. SHIPBUILDING AND REPAIR INDUSTRY

  8. Intermediate hearth repair technique at Thyssen Stahl AG

    SciTech Connect (OSTI)

    Kowalski, W.; Bachhofen, H.J.; Ruether, P.; Ballewski, T. [Thyssen Stahl AG, Duisburg (Germany)

    1996-12-31

    Nowadays various techniques for the fastest possible intermediate repair and/or emplacement of refractory materials above the tuyere level allow a significant extension of furnace campaign life. The latter are hence now exclusively determined by the service life of the hearth. The improvement of hearth monitoring and the estimation of residual brick strength of the refractory lining on the basis of temperature measurements in the hearth enable the location of individual zones of premature wear. These measurement methods, which were developed by Thyssen Stahl AG, aid the decision to undertake selective repair of the hearth. Three areas of repair are differentiated: taphole zone; hearth wall, localized; and hearth wall, extensive. This hearth repair method is described in this report using the example of hearth refurbishing blast furnace 8, Hamborn.

  9. Repair Sequences in American Learners of German Interlanguage

    E-Print Network [OSTI]

    Wisbey, Evelyn

    2010-04-25

    This study in Conversation Analysis investigates the organization of other-initiated repair sequences in American learners of German, i.e., it examines how learners deal with troubles in hearing or understanding that they ...

  10. Factories: The Shipbuilding and Ship-repairing Regulations 1960†

    E-Print Network [OSTI]

    Hare, John

    1960-01-01

    These Regulations revoke the Shipbuilding Regulations, 1931, which were designed for the safety, health and welfare of persons employed in the construction and repair of ships in sbipbuilding yards. The present Regulations, ...

  11. Development/Plasticity/Repair Dorsally and Ventrally Derived Oligodendrocytes Have

    E-Print Network [OSTI]

    Richardson, William D.

    Development/Plasticity/Repair Dorsally and Ventrally Derived Oligodendrocytes Have Similar derived oligodendrocyte (OL) lineage cells have different properties. We generated a dual reporter mouse line to color code ventrally and dorsally derived OLPs (vOLPs and d

  12. Repairs for damaged bolt holes in continuous fiber reinforced plastics†

    E-Print Network [OSTI]

    Copps, Kevin Daniel

    1992-01-01

    of fastened joints and to investigate previous techniques for the repair of continuous fiber reinforced plastics. LITERATURE REVIEW Characterizing Failure Modes There is very little agreement about what conditions constitute failure in composite joints... of possible methods for preventing and repairing fastener hole defects. Proper drilling technique The optimal drilling conditions for fiber reinforced parts are hard to control, and can differ depending on the structural application. The proper technique...

  13. Dofasco`s No. 4 blast furnace hearth breakout, repair and rescue

    SciTech Connect (OSTI)

    Donaldson, R.J.; Fischer, A.J.; Sharp, R.M.; Stothart, D.W. [Dofasco Inc., Hamilton, Ontario (Canada)

    1995-12-01

    On May 5, 1994, after producing 9.5 million metric tons of iron, Dofasco`s No. 4 Blast Furnace experienced a hearth breakout 250 millimeters below the west taphole. The hot metal spill caused a fire resulting in severe damage and 33 days of lost production. During a 26-day period, electrical wiring, water drainage systems and both tapholes were repaired. Recovery from an unprepared furnace stop of this length, with the deadman depleted is difficult. To aid with the rescue Hoogovens-designed oxygen/fuel lances were commissioned. The furnace recovery began with a lance in each taphole and all tuyeres plugged. Six days after startup the furnace was casting into torpedo cars, and after nine days operation had returned to normal. This incident prompted Dofasco to expand the hearth monitoring system to detect and prevent similar occurrences. During the repair, 203 new thermocouples were installed in the hearth, concentrating on the tapholes and elephant foot areas. These thermocouples were installed at various depths and locations to allow heat flux calculations. This hearth monitoring system has already identified other problem areas and provided valuable information about hearth drainage patterns. This information has allowed them to develop control strategies to manage localized problem areas.

  14. Exposure Evaluation for Benzene, Lead and Noise in Vehicle and Equipment Repair Shops

    SciTech Connect (OSTI)

    Sweeney, Lynn C.

    2013-04-10

    An exposure assessment was performed at the equipment and vehicle maintenance repair shops operating at the U. S. Department of Energy Hanford site, in Richland, Washington. The maintenance shops repair and maintain vehicles and equipment used in support of the Hanford cleanup mission. There are three general mechanic shops and one auto body repair shop. The mechanics work on heavy equipment used in construction, cranes, commercial motor vehicles, passenger-type vehicles in addition to air compressors, generators, and farm equipment. Services include part fabrication, installation of equipment, repair and maintenance work in the engine compartment, and tire and brake services. Work performed at the auto body shop includes painting and surface preparation which involves applying body filler and sanding. 8-hour time-weighted-average samples were collected for benzene and noise exposure and task-based samples were collected for lead dust work activities involving painted metal surfaces. Benzene samples were obtained using 3Mô 3520 sampling badges and were analyzed for additional volatile organic compounds. These compounds were selected based on material safety data sheet information for the aerosol products used by the mechanics for each day of sampling. The compounds included acetone, ethyl ether, toluene, xylene, VM&P naphtha, methyl ethyl ketone, and trichloroethylene. Laboratory data for benzene, VM&P naphtha, methyl ethyl ketone and trichloroethylene were all below the reporting detection limit. Airborne concentrations for acetone, ethyl ether, toluene and xylene were all less than 10% of their occupational exposure limit. The task-based samples obtained for lead dusts were submitted for a metal scan analysis to identify other metals that might be present. Laboratory results for lead dusts were all below the reporting detection limit and airborne concentration for the other metals observed in the samples were less than 10% of the occupational exposure limit. Noise dosimetry sampling was performed on a random basis and was representative of the different work activities within the four shops. Twenty three percent of the noise samples exceeded the occupational exposure limit of 85 decibels for an 8-hour time-weightedaverage. Work activities where noise levels were higher included use of impact wrenches and grinding wheels.

  15. Biochemical characterization of the E. coli Very Short Patch Repair pathway and its coordination with methyltransferase repair of 0?-methylguanine

    E-Print Network [OSTI]

    Rye, Peter Thomas

    2006-01-01

    The E. coli Very Short Patch Repair (VSPR) system corrects T:G mismatches that arise through Dcm-mediated methylation and subsequent deamination of the underlined cytosine residue in the palindromic sequence 5'-CCWGG-3' ...

  16. Assessment of airplane design, fabrication, and repair

    E-Print Network [OSTI]

    Stolar, Lauren (Lauren Elise)

    2009-01-01

    Engineering programs are most often classes dedicated to how to design things, while the topic of reverse engineering or problem solving is rarely discussed. This unequal presentation of two sides of the same discipline ...

  17. Mechanism Design for an Agnostic Planner: universal mechanisms, logarithmic equilibrium

    E-Print Network [OSTI]

    Cvitanic, Jaksa

    Mechanism Design for an Agnostic Planner: universal mechanisms, logarithmic equilibrium payoffs consider the problem of Bayesian mechanism design when the respondents share a com- mon prior about which concerned with the first issue, which connects our results to the literature on robust mechanism design

  18. On the geometry of the energy operator in quantum mechanics

    E-Print Network [OSTI]

    Vitolo, Raffaele

    with several contributions from many authors. 1 Introduction One of the problems of quantum mechanical theories

  19. Some integral geometry problems on Finsler and Riemannian ...

    E-Print Network [OSTI]

    Yernat M. Assylbekov

    2012-06-23

    Institute of Mathematics Informatics and Mechanics. Kazakhstan. Joint work with Nurlan Dairbekov. Yernat M. Assylbekov. Integral geometry problems on Finsler†...

  20. LABORATORY II MECHANICAL OSCILLATIONS

    E-Print Network [OSTI]

    Minnesota, University of

    Lab II - 1 LABORATORY II MECHANICAL OSCILLATIONS Most of the laboratory problems so far have was constant. In this set of laboratory problems, the total force acting on an object, and thus its's oscillation frequency. OBJECTIVES: After successfully completing this laboratory, you should be able to

  1. LENS repair and modification of metal NW components:materials and applications guide.

    SciTech Connect (OSTI)

    Smugeresky, John E. (Sandia National Laboratories, Livermore, CA); Gill, David Dennis; Oberhaus, Jason (BWXT Y-12); Adams, Thad (Savannah River National Laboratory); VanCamp, Chad (Kansas City Plant)

    2006-11-01

    Laser Engineered Net Shaping{trademark} (LENS{reg_sign}) is a unique, layer additive, metal manufacturing technique that offers the ability to create fully dense metal features and components directly from a computer solid model. LENS offers opportunities to repair and modify components by adding features to existing geometry, refilling holes, repairing weld lips, and many other potential applications. The material deposited has good mechanical properties with strengths typically slightly higher that wrought material due to grain refinement from a quickly cooling weld pool. The result is a material with properties similar to cold worked material, but without the loss in ductility traditionally seen with such treatments. Furthermore, 304L LENS material exhibits good corrosion resistance and hydrogen compatibility. This report gives a background of the LENS process including materials analysis addressing the requirements of a number of different applications. Suggestions are given to aid both the product engineer and the process engineer in the successful utilization of LENS for their applications. The results of testing on interface strength, machinability, weldability, corrosion resistance, geometric effects, heat treatment, and repair strategy testing are all included. Finally, the qualification of the LENS process is briefly discussed to give the user confidence in selecting LENS as the process of choice for high rigor applications. The testing showed LENS components to have capability in repair/modification applications requiring complex castings (W80-3 D-Bottle bracket), thin wall parts requiring metal to be rebuilt onto the part (W87 Firing Set Housing and Y-12 Test Rings), the filling of counterbores for use in reservoir reclamation welding (SRNL hydrogen compatibility study) and the repair of surface defects on pressure vessels (SRNL gas bottle repair). The material is machinable, as testing has shown that LENS deposited material machines similar to that of welded metal. Tool wear is slightly higher in LENS material than in wrought material, but not so much that one would be concerned with increased tooling cost. The LENS process achieved process qualification for the AY1E0125 D-Bottle Bracket from the W80-3 LEP program, and in the effort, also underwent testing in weapons environments. These tests included structural dynamic response testing and drop testing. The LENS deposited parts were compared in these tests with conventionally machined parts and showed equivalency to such an extent that the parts were accepted for use in parallel path subsystem-level weapon environment testing. The evaluation of LENS has shown that the process can be a viable option when either complete metal parts are needed or existing metal parts require modification or repair. The LENS Qualification Technology Investment team successfully investigated new applications for the LENS process and showed that it has great applicability across the Nuclear Weapons Complex as well as in other high rigor applications.

  2. Bayesian Algorithmic Mechanism Design [Extended Abstract

    E-Print Network [OSTI]

    Hartline, Jason D.

    Bayesian Algorithmic Mechanism Design [Extended Abstract] Jason D. Hartline Northwestern, Canada blucier@cs.toronto.edu ABSTRACT The principal problem in algorithmic mechanism design approach for designing incen- tive compatible mechanisms, namely that of Vickrey, Clarke, and Groves

  3. Model Order Reduction Methods for Meshfree Approximation of Problems with Singularities and Discontinuities

    E-Print Network [OSTI]

    Marodon, Camille

    2013-01-01

    Static Sin- gular Problems, Abstract and Presentation, 12th US National Congress of Computational Mechanics,

  4. Ice plug employed on subsea pipeline bend during repair

    SciTech Connect (OSTI)

    1997-12-22

    The first controlled-temperature ice plug in the bend of an offshore gas trunkline has been carried out for Phillips Petroleum Co. Norway on its Norpipe A.S. platform in the German sector of the North Sea. The procedure was part of a subsea valve repair operation. The ice plug was successfully formed offshore and tested to a differential pressure of 1,450 psi. Repair of two valves required only 5 days during which time gas production was operating at close to 50--60% via the platform bypass, says the service company. The paper discusses the procedure.

  5. Microfabricated therapeutic actuator mechanisms

    DOE Patents [OSTI]

    Northrup, Milton A. (Berkeley, CA); Ciarlo, Dino R. (Livermore, CA); Lee, Abraham P. (Walnut Creek, CA); Krulevitch, Peter A. (Los Altos, CA)

    1997-01-01

    Electromechanical microstructures (microgrippers), either integrated circuit (IC) silicon-based or precision machined, to extend and improve the application of catheter-based interventional therapies for the repair of aneurysms in the brain or other interventional clinical therapies. These micromechanisms can be specifically applied to release platinum coils or other materials into bulging portions of the blood vessels also known as aneurysms. The "micro" size of the release mechanism is necessary since the brain vessels are the smallest in the body. Through a catheter more than one meter long, the micromechanism located at one end of the catheter can be manipulated from the other end thereof. The microgripper (micromechanism) of the invention will also find applications in non-medical areas where a remotely actuated microgripper or similar actuator would be useful or where micro-assembling is needed.

  6. Microfabricated therapeutic actuator mechanisms

    DOE Patents [OSTI]

    Northrup, M.A.; Ciarlo, D.R.; Lee, A.P.; Krulevitch, P.A.

    1997-07-08

    Electromechanical microstructures (microgrippers), either integrated circuit (IC) silicon-based or precision machined, to extend and improve the application of catheter-based interventional therapies for the repair of aneurysms in the brain or other interventional clinical therapies. These micromechanisms can be specifically applied to release platinum coils or other materials into bulging portions of the blood vessels also known as aneurysms. The ``micro`` size of the release mechanism is necessary since the brain vessels are the smallest in the body. Through a catheter more than one meter long, the micromechanism located at one end of the catheter can be manipulated from the other end thereof. The microgripper (micromechanism) of the invention will also find applications in non-medical areas where a remotely actuated microgripper or similar actuator would be useful or where micro-assembling is needed. 22 figs.

  7. From Breaking Bad to Worse: Exploiting Homologous DNA Repair Deficiency in Cancer

    E-Print Network [OSTI]

    Hemann, Michael

    DNA repair deficiencies are common among cancer cells and represent a potential vulnerability that might be exploited by targeting compensatory repair pathways. However, the identification of synthetically lethal combinations ...

  8. Repair processes and radiation quality in neoplastic transformation of mammalian cells

    SciTech Connect (OSTI)

    Han, A.; Hill, C.K.; Elkind, M.M.

    1984-08-01

    Appropriate in vitro mammalian cell systems facilitate the study of cellular mechanisms of radiation oncogenesis. C3H 10T1/2 cells derived from mouse embryo have been used to study the effects of protracted irradiation on cell killing and incidence of neoplastic transformation. Protracted exposures of /sup 60/Co ..gamma.. rays or fission-spectrum neutrons (from the JANUS reactor at the Argonne National Laboratory) were given either at low dose rates or as multifractionated regimens using high dose rates. Dose protraction of ..gamma.. rays by multifractionation at a high dose rate (50 rad/min) results in appreciable reduction in cell killing and also significantly reduces the incidence of neoplastic transformation. Irradiation at a low dose rate has the same qualitative effect. In contrast, protracted exposures of fission-spectrum neutrons, given at a low dose rate (0.086 or 0.43 rad/min), result in significant enhancement of the frequency of transformation in the dose region of up to 80 rad. However, the survival of cells is essentially the same as that for the same single dose of neutrons given at a high dose rate. These observations are consistent with net ''error-free'' repair of transformational damage following protracted exposure of a low LET radiation and possibly a net ''error-prone'' repair of transformational damage after protracted irradiations with fission-spectrum neutrons.

  9. The cellular role of the specific immune system in fracture repair

    E-Print Network [OSTI]

    Gaston, Mark S

    2009-01-01

    This thesis embodies a novel investigation into the cellular role of the specific immune system in fracture repair....

  10. Development of quick repairing technique for ceramic burner in hot stove of blast furnace

    SciTech Connect (OSTI)

    Kondo, Atsushi; Doura, Kouji; Nakamura, Hirofumi [Sumitomo Metal Industries, Ltd., Wakayama (Japan). Wakayama Steel Works

    1997-12-31

    Refractories of ceramic burner in hot stoves at Wakayama No. 4 blast furnace were damaged. There are only three hot stoves, so repairing must be done in a short. Therefore, a quick repairing technique for ceramic burners has been developed, and two ceramic burners were repaired in just 48 hours.

  11. Attacking and Repairing the Improved ModOnions Protocol

    E-Print Network [OSTI]

    Borisov, Nikita

    Attacking and Repairing the Improved ModOnions Protocol Nikita Borisov1 , Marek Klonowski2 presented in ACNS 2008. The protocol itself was proposed as an improved version of ModOnions, which uses universal re-encryption in order to avoid replay attacks. How- ever, ModOnions allowed the detour attack

  12. Availability Analysis of Repairable Computer Systems and Stationarity Detection

    E-Print Network [OSTI]

    Sericola, Bruno

    Availability Analysis of Repairable Computer Systems and Stationarity Detection Bruno Sericola computer system and we assume, as usual, that the system is modeled by a finite Markov process. We propose of performability measures. Index Terms–Repairable computer systems, dependability, availability, performability

  13. Ancient bacteria show evidence of DNA repair Sarah Stewart Johnson*

    E-Print Network [OSTI]

    Nielsen, Rasmus

    Ancient bacteria show evidence of DNA repair Sarah Stewart Johnson* , Martin B. Hebsgaard , Torben for review June 14, 2007) Recent claims of cultivable ancient bacteria within sealed environ- ments highlight-term survival of bacteria sealed in frozen conditions for up to one million years. Our results show evidence

  14. Development/Plasticity/Repair Analogous Synaptic Plasticity Profiles Emerge from

    E-Print Network [OSTI]

    Narayanan, Rishikesh

    Development/Plasticity/Repair Analogous Synaptic Plasticity Profiles Emerge from Disparate Channel Institute of Technology, Calicut 637 601, India, and 3Bio-Medical Technology Wing, Sree Chitra Thirunal Institute for Medical Science & Technology, Trivandrum 695 012, India An open question within

  15. Development/Plasticity/Repair Group I Metabotropic Glutamate Receptors Control

    E-Print Network [OSTI]

    Grau, James

    Development/Plasticity/Repair Group I Metabotropic Glutamate Receptors Control Metaplasticity the spinal cord can support several forms of plasticity, including response≠outcome (instrumental) learning. This inhibi- tion of plasticity in spinal learning is itself a form of plasticity that requires i

  16. http://nnr.sagepub.com Neurorehabilitation and Neural Repair

    E-Print Network [OSTI]

    Prochazka, Arthur

    displayed on a computer.The time taken to move to and click on each target was recorded. Results. The use of Neurorehabilitation can be found at:Neurorehabilitation and Neural RepairAdditional services and information for http/2/188Citations at UNIV OF ALBERTA LIBRARY on February 18, 2010http://nnr.sagepub.comDownloaded from #12;Research

  17. Development/Plasticity/Repair Identification of Nicotinic Acetylcholine Receptor Recycling

    E-Print Network [OSTI]

    Alford, Simon

    Development/Plasticity/Repair Identification of Nicotinic Acetylcholine Receptor Recycling and Its plasticity; however, the recycling of receptors has never been observed at peripheral synapses. Using a novel the regulation of receptor density, which could lead to rapid alterations in synaptic efficacy. Key words: toxin

  18. Simplification and Repair of Polygonal Models Using Volumetric Techniques

    E-Print Network [OSTI]

    California at Berkeley, University of

    Simplification and Repair of Polygonal Models Using Volumetric Techniques Fakir S. Nooruddin a method for converting polygonal models to a volumetric representation in a way that handles models by converting a model to and from the volumetric domain. We also describe a new topology-altering simplification

  19. & Mechanical Engineering

    E-Print Network [OSTI]

    Zhou, Chongwu

    AME Aerospace & Mechanical Engineering #12;Aerospace and Mechanical Engineers design complex mechanical, thermal, uidic, acoustical, optical, and electronic systems, with characteristic sizes ranging and far underground, to near-Earth, planetary, interplanetary and galactic space. Aerospace and Mechanical

  20. Nuclear Problems in Astrophysics

    E-Print Network [OSTI]

    W. C. Haxton

    2003-01-03

    These lectures, presented at the International School of Physics ``Enrico Fermi,'' deal with two major themes. The first is the remarkable story of the solar neutrino problem, which (along with the atmospheric neutrino anomaly) recently led to the discovery of massive neutrinos and neutrino oscillations, physics beyond the standard model. I will describe the physics of the standard solar model (SSM), the experimental program that was motivated by the discrepancies between SSM predictions and the initial observations of Raymond Davis, Jr., and his colleagues, and the recent results of SNO and SuperKamiokande. These first lectures end with a description of what we have learned about neutrino oscillations and the neutrino mass matrix, as well as the open questions (neutrino charge conjugation properties, the absolute mass scale, CP violation) that could ultimately impact our understanding of baryogenesis, the origin of large-scale structure, and other topics in cosmology and astrophysics. The second theme is the core-collapse supernova mechanism and associated nucleosynthesis. This problem connects neutrino physics, which controls much of the nuclear physics of the star, with the long-term chemical evolution of our galaxy. In particular, the $r$-process, which produces about half of the heavy elements, remains poorly understood, despite important new constraints from studies of metal-poor halo stars. The possible role of new neutrino properties on both the explosion mechanism and nucleosynthesis is noted.

  1. Teaching Computer-Aided Mechanism Design and

    E-Print Network [OSTI]

    Cheng, Harry H.

    Teaching Computer-Aided Mechanism Design and Analysis Using a High-Level Mechanism Toolkit MATT into a course on mechanism analysis and design is presented. Mechanism analysis is enhanced when coupled computing environment. By solving mechanism design problems in C/C√ĺ√ĺ, the programming skills gained

  2. UTILITIES PROBLEMS AND FAILURES Electrical or plumbing failure/Flooding/Water leak/Natural gas

    E-Print Network [OSTI]

    Fernandez, Eduardo

    UTILITIES PROBLEMS AND FAILURES Electrical or plumbing failure/Flooding/Water leak/Natural gas for electrical shock. NOTIFY University Police. What should I do if I smell natural or propane gas? LEAVE/Repair line, 7-6333, or CALL the Campus University Police or Security at (561) 297-3500 or 911

  3. Applied Probability Trust (4 February 2008) INDEX POLICIES FOR DISCOUNTED BANDIT PROBLEMS

    E-Print Network [OSTI]

    Powell, Warren B.

    . Then it is assumed that arms may break down, but repair is an option at some cost, and the new Whittle index policyApplied Probability Trust (4 February 2008) INDEX POLICIES FOR DISCOUNTED BANDIT PROBLEMS/action-dependent probabilities. It is proven that no index policy can attain the maximum expected total discounted reward

  4. Problem Solving Framework Read the problem carefully.

    E-Print Network [OSTI]

    Minnesota, University of

    Problem Solving Framework Read the problem carefully. Draw a useful picture (sketch) that shows how identified in Step 1. 1. Understand the Problem 2. Analyze the Problem 3. Construct a Solution Apply constraint equations) to eliminate the unwanted unknowns? Use math (algebra/calculus) to solve for target

  5. Development of a rapid design procedure for emergency repair of bridge columns using fiber-reinforced polymers

    E-Print Network [OSTI]

    Slater, Susan E.

    2008-01-01

    ACI), Building Research Establishment, Ltd. (BRE), Concrete Society and International Concrete Repair Institute jointly publish standards

  6. Bohmian Mechanics

    E-Print Network [OSTI]

    Detlef Duerr; Sheldon Goldstein; Roderich Tumulka; Nino Zanghi

    2009-03-15

    Bohmian mechanics is a theory about point particles moving along trajectories. It has the property that in a world governed by Bohmian mechanics, observers see the same statistics for experimental results as predicted by quantum mechanics. Bohmian mechanics thus provides an explanation of quantum mechanics. Moreover, the Bohmian trajectories are defined in a non-conspiratorial way by a few simple laws.

  7. Quantum Computing: Solving Complex Problems

    ScienceCinema (OSTI)

    DiVincenzo, David [IBM Watson Research Center

    2009-09-01

    One of the motivating ideas of quantum computation was that there could be a new kind of machine that would solve hard problems in quantum mechanics. There has been significant progress towards the experimental realization of these machines (which I will review), but there are still many questions about how such a machine could solve computational problems of interest in quantum physics. New categorizations of the complexity of computational problems have now been invented to describe quantum simulation. The bad news is that some of these problems are believed to be intractable even on a quantum computer, falling into a quantum analog of the NP class. The good news is that there are many other new classifications of tractability that may apply to several situations of physical interest.

  8. Testing and evaluation of grout repaired tubular members†

    E-Print Network [OSTI]

    Nunn, John Mansfield

    1992-01-01

    of Failed Weld Seam page 64 65 66 69 73 74 80 82 31 Ideahzed Tubular Dented Member for the Taby, Zhou, and the Parsanejad Methods. . . . . . . . . . . . . . , . 92 32 Dent Geometry for the Elhnas Method 96 33 Experimental Ultimate Capamty vs P... commonly used to repiur damaged tubular members. These include 1 ) welding a sleeve around the outside of the member in the location of the damage, 2 ) applying an externally grouted clamp, and 3 ) applying internal grout Ideally, the repair method...

  9. Providing protection: Agencies receive funding to repair, upgrade dams†

    E-Print Network [OSTI]

    Wythe, Kathy

    2009-01-01

    by Kathy Wythe tx H2O | pg. 26 Providing protection Agencies receive funding to repair, upgrade dams along with local partners, can apply for grant funds, he said. Construction of the dams began through four federal authorizations passed between... 1944 and 1981. Land rights were acquired from landowners, and local agencies constructed the dams with federal money from NRCS (formerly the Soil Conservation Service). Local sponsors?including cities, counties, local soil and water conservation...

  10. the problem Solving the

    E-Print Network [OSTI]

    Goddard, Wayne

    the problem Solving the rephrased problem A spectrum of generalizations Further improvements Improving Brooks Landon Rabern A prison problem Some background The Ore-degree Rephrasing the problem Solving background 3 The Ore-degree 4 Rephrasing the problem 5 Solving the rephrased problem Kierstead and Kostochka

  11. Quantum Mechanics Without Observers

    E-Print Network [OSTI]

    W. H. Sulis

    2013-03-03

    The measurement problem and the role of observers have plagued quantum mechanics since its conception. Attempts to resolve these have introduced anthropomorphic or non-realist notions into physics. A shift of perspective based upon process theory and utilizing methods from combinatorial games, interpolation theory and complex systems theory results in a novel realist version of quantum mechanics incorporating quasi-local, nondeterministic hidden variables that are compatible with the no-hidden variable theorems and relativistic invariance, and reproduce the standard results of quantum mechanics to a high degree of accuracy without invoking observers.

  12. Interactive Bayesian identification of kinematic mechanisms

    E-Print Network [OSTI]

    BarragŠn, Patrick R

    2015-01-01

    This thesis addresses the problem of identifying mechanisms based on data gathered from a robot's interaction with them. We present a decision-theoretic formulation of this problem, using Bayesian filtering techniques to ...

  13. Contract and Mechanism Design in Settings with Multi-Period Trade

    E-Print Network [OSTI]

    Watson, Joel

    2006-01-01

    V . Q standard, static mechanism-design problems. First, weWatson, ďHard Evidence and Mechanism Design,Ē UCSD WorkingWatson, J. , ďContract, Mechanism Design, and Technological

  14. Senior Mechanical Engineer Company Description

    E-Print Network [OSTI]

    Kostic, Milivoje M.

    for manufacturability and familiarity with six-sigma tools preferred. ∑ Strong analytical and problem solving skills-on experience developing and launching electro-mechanical products, preferable in military or automotive

  15. Cooperative Problem Solving

    E-Print Network [OSTI]

    Minnesota, University of

    Chapter 2 Cooperative Problem Solving Page I. How do I coach students in problem solving? 13 II in Problem Solving? Your role during discussion and lab sessions is to coach students in physics problem solving, particularly the qualitative analysis of the problem. That is, you want to coach students so

  16. Cooperative Problem Solving

    E-Print Network [OSTI]

    Minnesota, University of

    Chapter 2 Cooperative Problem Solving Page I. How do I coach students in problem solving? 13 II Students in Problem Solving? Your role during discussion and lab sessions is to coach students in physics problem solving, particularly the qualitative analysis of the problem. That is, you want to coach students

  17. Continuum Mechanics Unit code: MATH45061

    E-Print Network [OSTI]

    Sidorov, Nikita

    MATH45061 Continuum Mechanics Unit code: MATH45061 Credit Rating: 15 Unit level: Level 4 Teaching concerns the formulation and solution of problems in continuum mechanics (solid and fluid mechanics) from equations. Overview This unit describes the fundamental theory of continuum mechanics in a unified

  18. WPN 12-9: Weatherization Assistance Program Incidental Repair Measure Guidance

    Broader source: Energy.gov [DOE]

    To provide guidance on incidental repair measures (IRM) allowable under the U.S. Department of Energy Weatherization Assistance Program (WAP).

  19. adaptation of DNA repair Byrne, Rose T; Klingele, Audrey J; Cabot...

    Office of Scientific and Technical Information (OSTI)

    Evolution of extreme resistance to ionizing radiation via genetic adaptation of DNA repair Byrne, Rose T; Klingele, Audrey J; Cabot, Eric L; Schackwitz, Wendy S; Martin, Jeffrey A;...

  20. Brain necrosis after fractionated radiation therapy: Is the halftime for repair longer than we thought?

    SciTech Connect (OSTI)

    Bender, Edward T.

    2012-11-15

    Purpose: To derive a radiobiological model that enables the estimation of brain necrosis and spinal cord myelopathy rates for a variety of fractionation schemes, and to compare repair effects between brain and spinal cord. Methods: Sigmoidal dose response relationships for brain radiation necrosis and spinal cord myelopathy are derived from clinical data using nonlinear regression. Three different repair models are considered and the repair halftimes are included as regression parameters. Results: For radiation necrosis, a repair halftime of 38.1 (range 6.9-76) h is found with monoexponential repair, while for spinal cord myelopathy, a repair halftime of 4.1 (range 0-8) h is found. The best-fit alpha beta ratio is 0.96 (range 0.24-1.73)Conclusions: A radiobiological model that includes repair corrections can describe the clinical data for a variety of fraction sizes, fractionation schedules, and total doses. Modeling suggests a relatively long repair halftime for brain necrosis. This study suggests that the repair halftime for late radiation effects in the brain may be longer than is currently thought. If confirmed in future studies, this may lead to a re-evaluation of radiation fractionation schedules for some CNS diseases, particularly for those diseases where fractionated stereotactic radiation therapy is used.

  1. Development/Plasticity/Repair Identification of Modulators of Hair Cell Regeneration in the

    E-Print Network [OSTI]

    Rubel, Edwin

    Development/Plasticity/Repair Identification of Modulators of Hair Cell Regeneration levels, environmental toxins, and some medications can readily induce damage or loss of hair cells, often

  2. Development/Plasticity/Repair Glycine Transporter-1 Inhibition Promotes Striatal Axon

    E-Print Network [OSTI]

    Sulzer, David

    Development/Plasticity/Repair Glycine Transporter-1 Inhibition Promotes Striatal Axon Sprouting via injections of the toxin 6-hydroxydopamine. We used apharmacologicalapproachtoenhance

  3. Will It Reach the Top? Prediction in the Mechanics World.†

    E-Print Network [OSTI]

    Bundy, Alan

    We describe an extension of a mechanics problem solving program to the set of ďroller coasterĒ problems, i.e. problems about the motion of a particle on a complex path. The reasoning strategy adopted by the program is ...

  4. Bohmian mechanics contradicts quantum mechanics

    E-Print Network [OSTI]

    Neumaier, Arnold

    Bohmian mechanics contradicts quantum mechanics Arnold Neumaier Institut fur Mathematik, Universit://solon.cma.univie.ac.at/#24;neum/ Abstract. It is shown that, for a harmonic oscillator in the ground state, Bohmian mechanics and quantum mechanics predict values of opposite sign for certain time correlations. The discrepancy can

  5. Effects of Surgical Repair or Reconstruction on Radiocarpal Mechanics from Wrists with Scapholunate Ligament Injury

    E-Print Network [OSTI]

    Johnson, Joshua

    2013-05-31

    ) and finite element modeling (FEM). The modeling process required geometries, boundary conditions and a contact relationship. Magnetic resonance imaging (MRI) was used to acquire images of the normal, injured and post-operative wrists, while relaxed and during...

  6. Problem Solving, Spring 1996

    E-Print Network [OSTI]

    Suppose a problem is worth p points. If the student cannot solve the problem and states "I can't solve the problem because of .... ", he or she will be rewarded†...

  7. Regularizing Inverse Problems

    E-Print Network [OSTI]

    Wang, Fang

    2014-06-26

    inverse problem to optimization problems of minimizing the norm of the data misfit plus a weighted regularization functional that incorporates the a priori information we may have about the original problem. The choices of the regularization functional r(q...

  8. Blade reliability collaborative : collection of defect, damage and repair data.

    SciTech Connect (OSTI)

    Ashwill, Thomas D.; Ogilvie, Alistair B.; Paquette, Joshua A.

    2013-04-01

    The Blade Reliability Collaborative (BRC) was started by the Wind Energy Technologies Department of Sandia National Laboratories and DOE in 2010 with the goal of gaining insight into planned and unplanned O&M issues associated with wind turbine blades. A significant part of BRC is the Blade Defect, Damage and Repair Survey task, which will gather data from blade manufacturers, service companies, operators and prior studies to determine details about the largest sources of blade unreliability. This report summarizes the initial findings from this work.

  9. The rebuilding and repairing of electric motors and generators

    E-Print Network [OSTI]

    Ridenour, Roy Everett

    1918-01-01

    Motor After Coils had been Put Back in Place In the repairing and rebuilding of electric motors and generators there are three principal factors which must be considered. These factors are, service, cost and reliability. If a machine can easily... motor. This motor had been through a fire in a Cripple Creek mine. The insulation had been burned from the coils except in the slots where mica had been used. The solder was*melted from the rotor and the babbitt from the bearings. Water had been...

  10. Statistical mechanics based on fractional classical and quantum mechanics

    SciTech Connect (OSTI)

    Korichi, Z.; Meftah, M. T.

    2014-03-15

    The purpose of this work is to study some problems in statistical mechanics based on the fractional classical and quantum mechanics. At first stage we have presented the thermodynamical properties of the classical ideal gas and the system of N classical oscillators. In both cases, the Hamiltonian contains fractional exponents of the phase space (position and momentum). At the second stage, in the context of the fractional quantum mechanics, we have calculated the thermodynamical properties for the black body radiation, studied the Bose-Einstein statistics with the related problem of the condensation and the Fermi-Dirac statistics.

  11. A physical approach to Tsirelson's problem

    E-Print Network [OSTI]

    Miguel Navascues; Tom Cooney; David Perez-Garcia; Ignacio Villanueva

    2011-05-17

    Tsirelson's problem deals with how to model separate measurements in quantum mechanics. In addition to its theoretical importance, the resolution of Tsirelson's problem could have great consequences for device independent quantum key distribution and certified randomness. Unfortunately, understanding present literature on the subject requires a heavy mathematical background. In this paper, we introduce quansality, a new theoretical concept that allows to reinterpret Tsirelson's problem from a foundational point of view. Using quansality as a guide, we recover all known results on Tsirelson's problem in a clear and intuitive way.

  12. Bid and Guess: A Nested Mechanism for King Solomon's Dilemma

    E-Print Network [OSTI]

    Qin, Cheng-Zhong

    2006-01-01

    of an Indivisible GoodĖA Mechanism Design Problem Underand Guess: A Nested Mechanism for King Solomonís Dilemma ?this paper we propose a mechanism to resolve King Solomonís

  13. FINITE FRACTURE MECHANICS OF MATRIX MICROCRACKING IN COMPOSITES

    E-Print Network [OSTI]

    Nairn, John A.

    FINITE FRACTURE MECHANICS OF MATRIX MICROCRACKING IN COMPOSITES JOHN A. NAIRN INTRODUCTION damage following complex loading conditions. This chapter describes a fracture mechanics approach to the microcracking problem. A complicating feature of composite fracture mechanics analysis is that laminates often

  14. Inter-individual variation in DNA repair capacity: A need for multi-pathway functional assays to promote translational DNA repair research

    E-Print Network [OSTI]

    Nagel, Zachary D.

    Why does a constant barrage of DNA damage lead to disease in some individuals, while others remain healthy? This article surveys current work addressing the implications of inter-individual variation in DNA repair capacity ...

  15. A Lightweight Network Repair Scheme for Data Collection Applications in ZigBee WSNs

    E-Print Network [OSTI]

    Tseng, Yu-Chee

    1 A Lightweight Network Repair Scheme for Data Collection Applications in ZigBee WSNs Meng networks (WSNs). In [4], a quick convergecast solution is proposed for data collection in a ZigBee beacon-enabled tree- based WSN. However, it does not consider the network repair issue. When a ZigBee router loses its

  16. On the Design of an Interactive, Patient-Specific Surgical Simulator for Mitral Valve Repair

    E-Print Network [OSTI]

    On the Design of an Interactive, Patient-Specific Surgical Simulator for Mitral Valve Repair Neil A repair of the mitral valve is a difficult procedure that is often avoided in favor of less effective valve replacement because of the associated technical challenges facing non-expert surgeons

  17. Cooperative Repair with Minimum-Storage Regenerating Codes for Distributed Storage

    E-Print Network [OSTI]

    Li, Baochun

    Cooperative Repair with Minimum-Storage Regenerating Codes for Distributed Storage Jun Li, Baochun--Distributed storage systems store redundant data to tolerate failures of storage nodes and lost data should be repaired when storage nodes fail. A class of MDS codes, called minimum- storage regenerating (MSR) codes

  18. Bridge Damage and Repair Costs from Hurricane Katrina Jamie Padgett1

    E-Print Network [OSTI]

    Padgett, Jamie Ellen

    Bridge Damage and Repair Costs from Hurricane Katrina Jamie Padgett1 ; Reginald DesRoches2 ; Bryant to repair or replace the bridges damaged during the hurricane is estimated at over $1 billion. This paper describes the observed damage patterns to bridges, including damage attributed to storm surge, wind, impact

  19. A Systematic Study of Automated Program Repair: Fixing 55 out of 105 Bugs for $8 Each

    E-Print Network [OSTI]

    New Mexico, University of

    maintenance, which consumes a daunting fraction of the total cost of software production [1]. AutomatedA Systematic Study of Automated Program Repair: Fixing 55 out of 105 Bugs for $8 Each Claire Le-source programs totaling 5.1 million lines of code and involving 10,193 test cases. GenProg automatically repairs

  20. Best Management Practices (BMPs) for Ship and Boat Building and Repair

    E-Print Network [OSTI]

    document for major British Columbia shipbuilding and repair facilities, Environment Canada has conducted a survey of existing practices at all shipbuilding facilities in B.C. (Peter Hatfield, 1993). These survey to the shipbuilding and repair industry. Many of the recommended practices are equally applicable to many other

  1. Mechanical Engineering 1 Mechanical Engineering

    E-Print Network [OSTI]

    Haller, Gary L.

    , for example, in novel gas turbine or electric hybrid vehicles--require that students understand the fundamentals of mechanics, thermodynamics, fluid mechanics, combustion, and materials science. In all members of the next generation of mechanical engineers. To implement this mission, the department adheres

  2. Solving Vibrational Problems... So easy!! Solving Vibrational Problems... So easy!!

    E-Print Network [OSTI]

    California at Santa Cruz, University of

    #12;Solving Vibrational Problems... So easy!! #12;Solving Vibrational Problems... So easy!! #12;Solving Vibrational Problems... So easy!! #12;Solving Vibrational Problems... So easy!! ...right? ∑ How

  3. Overview of Bohmian Mechanics

    E-Print Network [OSTI]

    Xavier Oriols; Jordi Mompart

    2013-01-09

    This chapter provides a comprehensive overview of the Bohmian formulation of quantum mechanics. It starts with a historical review of the difficulties found by Louis de Broglie, David Bohm, and John S. Bell to convince the scientific community about the validity and utility of Bohmian mechanics. Then, a formal explanation of Bohmian mechanics for nonrelativistic, single-particle quantum systems is presented. The generalization to many-particle systems, where the exchange interaction and the spin play an important role, is also presented. After that, the measurement process in Bohmian mechanics is discussed. It is emphasized that Bohmian mechanics exactly reproduces the mean value and temporal and spatial correlations obtained from the standard, that is the Copenhagen or orthodox, formulation. The ontological characteristics of Bohmian mechanics provide a description of measurements as another type of interaction without the need for introducing the wave function collapse. Several solved problems are presented at the end of the chapter, giving additional mathematical support to some particular issues. A detailed description of computational algorithms to obtain Bohmian trajectories from the numerical solution of the Schrodinger or the Hamilton-Jacobi equations are presented in an appendix. The motivation of this chapter is twofold: first, as a didactic introduction to Bohmian formalism, which is used in the subsequent chapters, and second, as a self-contained summary for any newcomer interested in using Bohmian mechanics in his or her daily research activity.

  4. Quadratic Inverse Eigenvalue Problems, Active Vibration Control and Model Updating

    E-Print Network [OSTI]

    Datta, Biswa

    is an important practical problem that arises in a wide range of applications, including mechanical vibrations control (AVC) and finite element model updating (FEMU) in mechanical vibration. The active vibrationQuadratic Inverse Eigenvalue Problems, Active Vibration Control and Model Updating Biswa N. Datta,1

  5. Proposal to negotiate an amendment to an existing blanket contract for the repair, recondioning or replacement of klystrons

    E-Print Network [OSTI]

    2012-01-01

    Proposal to negotiate an amendment to an existing blanket contract for the repair, recondioning or replacement of klystrons

  6. Bohmian mechanics contradicts quantum mechanics

    E-Print Network [OSTI]

    Arnold Neumaier

    2000-02-16

    It is shown that, for a harmonic oscillator in the ground state, Bohmian mechanics and quantum mechanics predict values of opposite sign for certain time correlations. The discrepancy can be explained by the fact that Bohmian mechanics has no natural way to accomodate the Heisenberg picture, since the local expectation values that define the beables of the theory depend on the Heisenberg time being used to define the operators. Relations to measurement are discussed, too, and shown to leave no loophole for claiming that Bohmian mechanics reproduces all predictions of quantum mechanics exactly.

  7. Evaluating indoor exposure modeling alternatives for LCA: A case study in the vehicle repair industry

    SciTech Connect (OSTI)

    Demou, Evangelia; Hellweg, Stefanie; Wilson, Michael P.; Hammond, S. Katharine; McKone, Thomas E.

    2009-05-01

    We evaluated three exposure models with data obtained from measurements among workers who use"aerosol" solvent products in the vehicle repair industry and with field experiments using these products to simulate the same exposure conditions. The three exposure models were the: 1) homogeneously-mixed-one-box model, 2) multi-zone model, and 3) eddy-diffusion model. Temporally differentiated real-time breathing zone volatile organic compound (VOC) concentration measurements, integrated far-field area samples, and simulated experiments were used in estimating parameters, such as emission rates, diffusivity, and near-field dimensions. We assessed differences in model input requirements and their efficacy for predictive modeling. The One-box model was not able to resemble the temporal profile of exposure concentrations, but it performed well concerning time-weighted exposure over extended time periods. However, this model required an adjustment for spatial concentration gradients. Multi-zone models and diffusion-models may solve this problem. However, we found that the reliable use of both these models requires extensive field data to appropriately define pivotal parameters such as diffusivity or near-field dimensions. We conclude that it is difficult to apply these models for predicting VOC exposures in the workplace. However, for comparative exposure scenarios in life-cycle assessment they may be useful.

  8. Computational Mechanism Design The classic mechanism design literature largely ignores computational considerations. It

    E-Print Network [OSTI]

    Chen, Yiling

    Chapter 3 Computational Mechanism Design The classic mechanism design literature largely ignores of computational mechanism design. Our goal is to use a market-based method, such as an auction, to compute' local problems Wel96 . The game-theoretic considera- tions of mechanism design were secondary

  9. RaDON --Repair and Diagnosis in Ontology Networks Qiu Ji, Peter Haase, Guilin Qi, Pascal Hitzler, Steffen Stadtmuller

    E-Print Network [OSTI]

    Hitzler, Pascal

    RaDON -- Repair and Diagnosis in Ontology Networks Qiu Ji, Peter Haase, Guilin Qi, Pascal Hitzler by integrating multiple distributed ontologies. Our RaDON system pro- vides functionalities to repair ontologies. To meet the above mentioned needs, we develop the RaDON system to repair and diagnose not only

  10. Applied Bohmian Mechanics

    E-Print Network [OSTI]

    A. Benseny; G. Albareda; A. S. Sanz; J. Mompart; X. Oriols

    2014-10-20

    Bohmian mechanics provides an explanation of quantum phenomena in terms of point particles guided by wave functions. This review focuses on the formalism of non-relativistic Bohmian mechanics, rather than its interpretation. Although the Bohmian and standard quantum theories have different formalisms, both give exactly the same predictions for all phenomena. Fifteen years ago, the quantum chemistry community began to study the practical usefulness of Bohmian mechanics. Since then, the scientific community has mainly applied it to study the (unitary) evolution of single-particle wave functions, either by developing efficient quantum trajectory algorithms or by providing a trajectory-based explanation of complicated quantum phenomena. Here we present a large list of examples showing how the Bohmian formalism provides a useful solution in different forefront research fields for this kind of problems (where the Bohmian and the quantum hydrodynamic formalisms coincide). In addition, this work also emphasizes that the Bohmian formalism can be a useful tool in other types of (non-unitary and nonlinear) quantum problems where the influence of the environment or the global wave function are unknown. This review contains also examples on the use of the Bohmian formalism for the many-body problem, decoherence and measurement processes. The ability of the Bohmian formalism to analyze this last type of problems for (open) quantum systems remains mainly unexplored by the scientific community. The authors of this review are convinced that the final status of the Bohmian theory among the scientific community will be greatly influenced by its potential success in these type of problems that present non-unitary and/or nonlinear quantum evolutions. A brief introduction of the Bohmian formalism and some of its extensions are presented in the last part of this review.

  11. Method of tissue repair using a composite material

    DOE Patents [OSTI]

    Hutchens, Stacy A; Woodward, Jonathan; Evans, Barbara R; O'Neill, Hugh M

    2014-03-18

    A composite biocompatible hydrogel material includes a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa. A calcium comprising salt is disposed in at least some of the pores. The porous polymer matrix can comprise cellulose, including bacterial cellulose. The composite can be used as a bone graft material. A method of tissue repair within the body of animals includes the steps of providing a composite biocompatible hydrogel material including a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa, and inserting the hydrogel material into cartilage or bone tissue of an animal, wherein the hydrogel material supports cell colonization in vitro for autologous cell seeding.

  12. Human HLTF mediates postreplication repair by its HIRAN domain-dependent replication fork remodelling

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Achar, Yathish Jagadheesh; Balogh, David; Neculai, Dante; Juhasz, Szilvia; Morocz, Monika; Gali, Himabindu; Dhe-Paganon, Sirano; Venclovas, ?eslovas; Haracska, Lajos

    2015-09-08

    Defects in the ability to respond properly to an unrepaired DNA lesion blocking replication promote genomic instability and cancer. Human HLTF, implicated in error-free replication of damaged DNA and tumour suppression, exhibits a HIRAN domain, a RING domain, and a SWI/SNF domain facilitating DNA-binding, PCNA-polyubiquitin-ligase, and dsDNA-translocase activities, respectively. Here, we investigate the mechanism of HLTF action with emphasis on its HIRAN domain. We found that in cells HLTF promotes the filling-in of gaps left opposite damaged DNA during replication, and this postreplication repair function depends on its HIRAN domain. Our biochemical assays show that HIRAN domain mutant HLTF proteinsmore†Ľretain their ubiquitin ligase, ATPase and dsDNA translocase activities but are impaired in binding to a model replication fork. These data and our structural study indicate that the HIRAN domain recruits HLTF to a stalled replication fork, and it also provides the direction for the movement of the dsDNA translocase motor domain for fork reversal. We suggest functional similarities between the HIRAN, the OB, the HARP2, and other domains found in certain motor proteins, which may explain why only a subset of DNA translocases can carry out fork reversal.ę†less

  13. The introduction of heat recoverable couplings to ship repair and maintenance

    SciTech Connect (OSTI)

    Liberatore, D.J.; Backerville, J.E.

    1982-12-01

    Although Heat Recoverable Couplings (HRCs), used to join pipe, may be labeled innovative ''state-of-the-art'' technology for U.S. Naval Shipyards, they have been in use in foreign ships and high technology industries for over a decade. HRCs provide a permanent leak-proof pipe joint in specified applications without the use of high temperature and the inherent hazards of an open flame. Manufactured from NITINOL, a nickel-titanium alloy developed by the U.S. Navy, the couplings exhibit a ''shape memory'' characteristic. That is, they return (shrink) to a specified shape (pipe diameter) thus forming a mechanical seal when the expanded coupling is removed from a cryogenic environment and warmed above approximately-130/sup 0/C. This paper provides background information into the development of NITINOL, technical explanation of shape memory metallurgy, and a summary of results, with specific examples, describing the trial use of HRCs at Pearl Harbor and Norfolk Naval Shipyards. Limited return cost data and recommendations for future use are presented. Then, using the HRC Program as a basis, the Authors discuss the conservative nature of the ship repair and maintenance environment. This environment, in the Authors' opinion, couples with complex contractual constraints and requirements which serve to restrict the introduction of new ideas. An analogy is made to Russian tenacity of recent years which promotes ''exploring and doing'' while we in the U.S. Navy are frequently content to study.

  14. Introduction Actual Industrial Problems

    E-Print Network [OSTI]

    Nigam, Nilima

    Introduction Actual Industrial Problems What's needed? Is there really interesting mathematics in Industry? Can mathematicians contribute to society, and do we want to...? Nilima Nigam Department Mathematics in Industry #12;Introduction Actual Industrial Problems What's needed? Some controversial

  15. Counting Problems involving Symmetry

    E-Print Network [OSTI]

    Donu Arapura

    2013-04-12

    Group theory can be applied to counting problems invloving symmetry. Here ... problem is to count the set of orbits H/S3. ... a partition of G. By corollary 3.10,.

  16. Counting Problems involving Symmetry*

    E-Print Network [OSTI]

    Group theory can be applied to counting problems invloving symmetry. Here ... problem is to count the set of orbits H/S3. .... a partition of G. By corollary 2.3,.

  17. Compliant mechanisms

    E-Print Network [OSTI]

    Venkataraghavan, Janarthanan T

    2001-01-01

    and a few mechanisms like a magneto active peristaltic pump, have been designed and tested for the first time using this material. In this mechanism, the pumping action is obtained when a moving magnetic field produces peristaltic waves in the magneto...

  18. Development and validation of bonded composite doubler repairs for commercial aircraft.

    SciTech Connect (OSTI)

    Roach, Dennis Patrick; Rackow, Kirk A.

    2007-07-01

    A typical aircraft can experience over 2,000 fatigue cycles (cabin pressurizations) and even greater flight hours in a single year. An unavoidable by-product of aircraft use is that crack, impact, and corrosion flaws develop throughout the aircraft's skin and substructure elements. Economic barriers to the purchase of new aircraft have placed even greater demands on efficient and safe repair methods. The use of bonded composite doublers offers the airframe manufacturers and aircraft maintenance facilities a cost effective method to safely extend the lives of their aircraft. Instead of riveting multiple steel or aluminum plates to facilitate an aircraft repair, it is now possible to bond a single Boron-Epoxy composite doubler to the damaged structure. The FAA's Airworthiness Assurance Center at Sandia National Labs (AANC), Boeing, and Federal Express completed a pilot program to validate and introduce composite doubler repair technology to the U.S. commercial aircraft industry. This project focused on repair of DC-10 fuselage structure and its primary goal was to demonstrate routine use of this repair technology using niche applications that streamline the design-to-installation process. As composite doubler repairs gradually appear in the commercial aircraft arena, successful flight operation data is being accumulated. These commercial aircraft repairs are not only demonstrating the engineering and economic advantages of composite doubler technology but they are also establishing the ability of commercial maintenance depots to safely adopt this repair technique. This report presents the array of engineering activities that were completed in order to make this technology available for widespread commercial aircraft use. Focused laboratory testing was conducted to compliment the field data and to address specific issues regarding damage tolerance and flaw growth in composite doubler repairs. Fatigue and strength tests were performed on a simulated wing repair using a substandard design and a flawed installation. In addition, the new Sol-Gel surface preparation technique was evaluated. Fatigue coupon tests produced Sol-Gel results that could be compared with a large performance database from conventional, riveted repairs. It was demonstrated that not only can composite doublers perform well in severe off-design conditions (low doubler stiffness and presence of defects in doubler installation) but that the Sol-Gel surface preparation technique is easier and quicker to carry out while still producing optimum bonding properties. Nondestructive inspection (NDI) methods were developed so that the potential for disbond and delamination growth could be monitored and crack growth mitigation could be quantified. The NDI methods were validated using full-scale test articles and the FedEx aircraft installations. It was demonstrated that specialized NDI techniques can detect flaws in composite doubler installations before they reach critical size. Probability of Detection studies were integrated into the FedEx training in order to quantify the ability of aircraft maintenance depots to properly monitor these repairs. In addition, Boeing Structural Repair and Nondestructive Testing Manuals were modified to include composite doubler repair and inspection procedures. This report presents the results from the FedEx Pilot Program that involved installation and surveillance of numerous repairs on operating aircraft. Results from critical NDI evaluations are reported in light of damage tolerance assessments for bonded composite doublers. This work has produced significant interest from airlines and aircraft manufacturers. The successful Pilot Program produced flight performance history to establish the durability of bonded composite patches as a permanent repair on commercial aircraft structures. This report discusses both the laboratory data and Pilot Program results from repair installations on operating aircraft to introduce composite doubler repairs into mainstream commercial aircraft use.

  19. MECHANICAL ENGINEERING What is Mechanical

    E-Print Network [OSTI]

    power plant energy conversion and generating systems; design, development, and manufactureof consumer of the broadest engineering fields. Mechanical engineers are found in virtually all productive industries, from

  20. DNA repair of a single UV photoproduct in a designed nucleosome

    SciTech Connect (OSTI)

    Kosmoskil, Joseph V.; Ackerman, Eric J. ); Smerdon, Michael J.

    2001-08-28

    Eukaryotic DNA repair enzymes must interact with the architectural hierarchy of chromatin. The challenge of finding damaged DNA complexed with histone proteins in nucleosomes is complicated by the need to maintain local chromatin structures involved in regulating other DNA processing events. The heterogeneity of lesions induced by DNA-damaging agents has led us to design homogeneously damaged substrates to directly compare repair of naked DNA with that of nucleosomes. Here we report that nucleotide excision repair in Xenopus nuclear extracts can effectively repair a single UV radiation photoproduct located 5 bases from the dyad center of a positioned nucleosome, although the nucleosome is repaired at about half the rate at which the naked DNA fragment is. Extract repair within the nucleosome is > 50-fold more rapid than either enzymatic photoreversal or endonuclease cleavage of the lesion in vitro. Furthermore, nucleosome formation occurs (after repair) only on damaged naked DNA ( 165-bp fragments) during a 1-h incubation in these extracts, even in the presence of a large excess of undamaged DNA. This is an example of selective nucleosome assembly by Xenopus nuclear extracts on a short linear DNA fragment containing a DNA lesion.

  1. Optimization Problems in Machine

    E-Print Network [OSTI]

    Grossmann, Ignacio E.

    classification l Optical character recognition l Automatically read digits in zip code l 256 dim vector of pixels #12;Binary classification problem + - Two sets of labeled points 2/15/12 EWO Seminar 2 #12;Binary classification problem + - How to label this new point? 2/15/12 EWO Seminar 3 #12;Binary classification problem

  2. Quantum Mechanics: Structures, Axioms and Paradoxes

    E-Print Network [OSTI]

    Aerts, Diederik

    Quantum Mechanics: Structures, Axioms and Paradoxes Diederik Aerts Center Leo Apostel, Brussels present an analysis of quantum mechanics and its problems and para- doxes taking into account the results a genuine incomplete- ness of standard quantum mechanics, however not an incompleteness that means

  3. Logic for Mechanism Design ---A Manifesto Marc Pauly and Michael Wooldridge

    E-Print Network [OSTI]

    Woolridge, Mike

    Logic for Mechanism Design --- A Manifesto Marc Pauly and Michael Wooldridge Department of Computer to mechanism design problems. We begin by reviewing the mechanism design problem, and discussing the issue issues for future research. 1. INTRODUCTION The problem of mechanism design, as understood and studied

  4. Logic for Mechanism Design --A Manifesto Marc Pauly and Michael Wooldridge

    E-Print Network [OSTI]

    Woolridge, Mike

    Logic for Mechanism Design -- A Manifesto Marc Pauly and Michael Wooldridge Department of Computer to mechanism design problems. We begin by reviewing the mechanism design problem, and discussing the issue issues for future research. 1. INTRODUCTION The problem of mechanism design, as understood and studied

  5. A Generalized Multiscale Finite Element Method for Poroelasticity Problems I: Linear Problems

    E-Print Network [OSTI]

    Brown, Donald L

    2015-01-01

    In this paper, we consider the numerical solution of poroelasticity problems that are of Biot type and develop a general algorithm for solving coupled systems. We discuss the challenges associated with mechanics and flow problems in heterogeneous media. The two primary issues being the multiscale nature of the media and the solutions of the fluid and mechanics variables traditionally developed with separate grids and methods. For the numerical solution we develop and implement a Generalized Multiscale Finite Element Method (GMsFEM) that solves problem on a coarse grid by constructing local multiscale basis functions. The procedure begins with construction of multiscale bases for both displacement and pressure in each coarse block. Using a snapshot space and local spectral problems, we construct a basis of reduced dimension. Finally, after multiplying by a multiscale partitions of unity, the multiscale basis is constructed in the offline phase and the coarse grid problem then can be solved for arbitrary forcin...

  6. Mechanical memory

    DOE Patents [OSTI]

    Gilkey, Jeffrey C. (Albuquerque, NM); Duesterhaus, Michelle A. (Albuquerque, NM); Peter, Frank J. (Albuquerque, NM); Renn, Rosemarie A. (Alburquerque, NM); Baker, Michael S. (Albuquerque, NM)

    2006-08-15

    A first-in-first-out (FIFO) microelectromechanical memory apparatus (also termed a mechanical memory) is disclosed. The mechanical memory utilizes a plurality of memory cells, with each memory cell having a beam which can be bowed in either of two directions of curvature to indicate two different logic states for that memory cell. The memory cells can be arranged around a wheel which operates as a clocking actuator to serially shift data from one memory cell to the next. The mechanical memory can be formed using conventional surface micromachining, and can be formed as either a nonvolatile memory or as a volatile memory.

  7. Mechanical memory

    DOE Patents [OSTI]

    Gilkey, Jeffrey C. (Albuquerque, NM); Duesterhaus, Michelle A. (Albuquerque, NM); Peter, Frank J. (Albuquerque, NM); Renn, Rosemarie A. (Albuquerque, NM); Baker, Michael S. (Albuquerque, NM)

    2006-05-16

    A first-in-first-out (FIFO) microelectromechanical memory apparatus (also termed a mechanical memory) is disclosed. The mechanical memory utilizes a plurality of memory cells, with each memory cell having a beam which can be bowed in either of two directions of curvature to indicate two different logic states for that memory cell. The memory cells can be arranged around a wheel which operates as a clocking actuator to serially shift data from one memory cell to the next. The mechanical memory can be formed using conventional surface micromachining, and can be formed as either a nonvolatile memory or as a volatile memory.

  8. Final Report for DOE Grant DE-FG02-03ER25579; Development of High-Order Accurate Interface Tracking Algorithms and Improved Constitutive Models for Problems in Continuum Mechanics with Applications to Jetting

    SciTech Connect (OSTI)

    Puckett, Elbridge Gerry; Miller, Gregory Hale

    2012-10-14

    Much of the work conducted under the auspices of DE-FG02-03ER25579 was characterized by an exceptionally close collaboration with researchers at the Lawrence Berkeley National Laboratory (LBNL). For example, Andy Nonaka, one of Professor Miller's graduate students in the Department of Applied Science at U. C. Davis (UCD) wrote his PhD thesis in an area of interest to researchers in the Applied Numerical Algorithms Group (ANAG), which is a part of the National Energy Research Supercomputer Center (NERSC) at LBNL. Dr. Nonaka collaborated closely with these researchers and subsequently published the results of this collaboration jointly with them, one article in a peer reviewed journal article and one paper in the proceedings of a conference. Dr. Nonaka is now a research scientist in the Center for Computational Sciences and Engineering (CCSE), which is also part of the National Energy Research Supercomputer Center (NERSC) at LBNL. This collaboration with researchers at LBNL also included having one of Professor Puckett's graduate students in the Graduate Group in Applied Mathematics (GGAM) at UCD, Sarah Williams, spend the summer working with Dr. Ann Almgren, who is a staff scientist in CCSE. As a result of this visit Sarah decided work on a problem suggested by the head of CCSE, Dr. John Bell, for her PhD thesis. Having finished all of the coursework and examinations required for a PhD, Sarah stayed at LBNL to work on her thesis under the guidance of Dr. Bell. Sarah finished her PhD thesis in June of 2007. Writing a PhD thesis while working at one of the University of California (UC) managed DOE laboratories is long established tradition at UC and Professor Puckett has always encouraged his students to consider doing this. Another one of Professor Puckett's graduate students in the GGAM at UCD, Christopher Algieri, was partially supported with funds from DE-FG02-03ER25579 while he wrote his MS thesis in which he analyzed and extended work originally published by Dr. Phillip Colella, the head of ANAG, and some of his colleagues. Chris Algieri is now employed as a staff member in Dr. Bill Collins' Climate Science Department in the Earth Sciences Division at LBNL working with computational models of climate change. Finally, it should be noted that the work conducted by Professor Puckett and his students Sarah Williams and Chris Algieri and described in this final report for DOE grant # DE-FC02-03ER25579 is closely related to work performed by Professor Puckett and his students under the auspices of Professor Puckett's DOE SciDAC grant DE-FC02-01ER25473 An Algorithmic and Software Framework for Applied Partial Differential Equations: A DOE SciDAC Integrated Software Infrastructure Center (ISIC). Dr. Colella was the lead PI for this SciDAC grant, which was comprised of several research groups from DOE national laboratories and five university PI's from five different universities. In theory Professor Puckett tried to use funds from the SciDAC grant to support work directly involved in implementing algorithms developed by members of his research group at UCD as software that might be of use to Puckett's SciDAC CoPIs. (For example, see the work reported in Section 2.2.2 of this final report.) However, since there is considerable lead time spent developing such algorithms before they are ready to become `software' and research plans and goals change as the research progresses, Professor Puckett supported each member of his research group partially with funds from the SciDAC APDEC ISIC DE-FC02-01ER25473 and partially with funds from this DOE MICS grant DE-FC02-03ER25579. This has necessarily resulted in a significant overlap of project areas that were funded by both grants. In particular, both Sarah Williams and Chris Algieri were supported partially with funds from grant # DE-FG02-03ER25579, for which this is the final report, and in part with funds from Professor Puckett's DOE SciDAC grant # DE-FC02-01ER25473. For example, Sarah Williams received support from DE-FC02- 01ER25473 and DE-FC02-03ER25579, both while at UCD taking cla

  9. Modeling Planarization in Chemical-Mechanical Leonard Borucki

    E-Print Network [OSTI]

    , 2002 Abstract A mathematical model for chemical-mechanical polishing is developed. The ef- fects of padModeling Planarization in Chemical-Mechanical Polishing Leonard Borucki , Dilek Alagoz , Stephanie and compared to experimental data. 1 Problem Description 1.1 Physical Problem Chemical-mechanical polishing

  10. Mechanism Design Based on Beliefs about Responsive Play (Position Paper)

    E-Print Network [OSTI]

    Vorobeychik, Eugene

    Mechanism Design Based on Beliefs about Responsive Play (Position Paper) Yevgeniy Vorobeychik incompletely spec- ifies a mechanism design problem. The designer must consider which among a multiplicity that designers embrace the corre- sponding forecasting problem and evaluate candidate mechanisms with respect

  11. Modeling and centralization of strategic inventory for repairable and long lead-time spare parts

    E-Print Network [OSTI]

    Duncan, Tyeliah Elaine

    2011-01-01

    This thesis develops an optimal inventory model for repairable and long leadtime spare parts for an Engine overhaul business. In addition, it presents a business case for centralization of inventory. Pratt & Whitney purchased ...

  12. The COP9 signalosome is vital for timely repair of DNA double-strand breaks

    E-Print Network [OSTI]

    Meir, Michal; Galanty, Yaron; Kashani, Lior; Blank, Michael; Khosravi, Rami; FernŠndez-Ńvila, MarŪa Jesķs; Cruz-GarcŪa, Andrťs; Star, Ayelet; Shochot, Lea; Thomas, Yann; Garrett, Lisa J.; Chamovitz, Daniel A.; Bodine, David M.; Kurz, Thimo; Huertas, Pablo; Ziv, Yael; Shiloh, Yosef

    2015-04-08

    is critical for proper DSB repair, and that loss of this phosphorylation site alone is sufficient to cause a DDR deficiency phenotype in the mouse. This novel branch of the DSB response thus significantly affects genome stability....

  13. Review of Maintenance and Repair Times for Components in Technological Facilities

    SciTech Connect (OSTI)

    L. C. Cadwallader

    2012-11-01

    This report is a compilation of some unique component repair time data and it also presents citations of more extensive reports where lists of repair times can be found. This collection of information should support analysts who seek to quantify maintainability and availability of high technology and nuclear energy production systems. While there are newer sources of repair time information, most, if not all, of the newer sources are proprietary and cannot be shared. This report offers data that, while older, is openly accessible and can serve as reasonable estimates of repair times, at least for initial studies. Some times were found for maintenance times in radiation environments, and some guidance for multiplicative factors to use to account for work in contamination areas.

  14. Tiny Terminators: New Micro-Robots Assemble, Repair Themselves and Are Surprisingly Strong

    Broader source: Energy.gov [DOE]

    Tiny robots that can assemble and repair themselves? Watch a video of Argonne National Laboratory's micro-robots that easily perform tasks that can challenge other robots, including moving objects that are larger than themselves.

  15. Bruce Podwal Seminar Series Implementing Emergency Foundation Repairs on I-495 in Delaware

    E-Print Network [OSTI]

    Sun, Yi

    to be misaligned. Delaware Department of Transportation (DelDOT) responded immediately by shutting down the bridgeBruce Podwal Seminar Series Implementing Emergency Foundation Repairs on I-495 in Delaware Tuesday

  16. Use of CFRP Overlays to Repair Fatigue Damage in Steel Bridge Girders and Components

    E-Print Network [OSTI]

    Gangel, Regan Elisabeth

    2012-05-31

    Fatigue damage in steel girder bridges built prior to the mid-1980s is common due to distortion-induced fatigue. Different repair techniques have been developed and implemented to retrofit bridges of this era with existing ...

  17. REPAIR OF BRIDGE STEEL GIRDERS DAMAGED BY DISTORTION-INDUCED FATIGUE

    E-Print Network [OSTI]

    Alemdar, Fatih

    2011-12-31

    This study investigates the repair of steel bridge girders damaged by distortion-induced fatigue. The study is presented in three parts. The first part describes finite element modeling techniques used to evaluate the ...

  18. Plug repairs of marine glass fiber / vinyl ester laminates subjected to uniaxial tension

    E-Print Network [OSTI]

    Michelis, Alexandros

    2009-01-01

    Glass fiber/vinyl ester composite laminates are currently being used and proposed for the hulls, bulkheads, and superstructures of large ships. This thesis examines the effectiveness of the repair of such laminates using ...

  19. Inorganic-Organic Shape Memory Polymers and Foams for Bone Defect Repairs

    E-Print Network [OSTI]

    Zhang, Dawei

    2013-04-16

    The ultimate goal of this research was to develop a ďself-fittingĒ shape memory polymer (SMP) scaffold for the repair of craniomaxillofacial (CMF) bone defects. CMF defects may be caused by trauma, tumor removal or congenital abnormalities...

  20. Community-Minded Interns at Savannah River Site Help Area Residents in Need with Home Repairs

    Broader source: Energy.gov [DOE]

    AIKEN, S.C. Ė More than two dozen college interns who worked at the Savannah River Site (SRS) this summer joined other volunteers and headed into area neighborhoods to help people in need with home repairs.

  1. RESTORING A DAMAGED 16-YEAR -OLD INSULATING POLYMER CONCRETE DIKE OVERLAY: REPAIR MATERIALS AND TECHNOLOGIES.

    SciTech Connect (OSTI)

    SUGAMA,T.

    2007-01-01

    The objective of this program was to design and formulate organic polymer-based material systems suitable for repairing and restoring the overlay panels of insulating lightweight polymer concrete (ILPC) from the concrete floor and slope wall of a dike at KeySpan liquefied natural gas (LNG) facility in Greenpoint, Brooklyn, NY, just over sixteen years ago. It also included undertaking a small-scale field demonstration to ensure that the commercial repairing technologies were applicable to the designed and formulated materials.

  2. Relativistic viscoelastic fluid mechanics

    E-Print Network [OSTI]

    Masafumi Fukuma; Yuho Sakatani

    2011-09-01

    A detailed study is carried out for the relativistic theory of viscoelasticity which was recently constructed on the basis of Onsager's linear nonequilibrium thermodynamics. After rederiving the theory using a local argument with the entropy current, we show that this theory universally reduces to the standard relativistic Navier-Stokes fluid mechanics in the long time limit. Since effects of elasticity are taken into account, the dynamics at short time scales is modified from that given by the Navier-Stokes equations, so that acausal problems intrinsic to relativistic Navier-Stokes fluids are significantly remedied. We in particular show that the wave equations for the propagation of disturbance around a hydrostatic equilibrium in Minkowski spacetime become symmetric hyperbolic for some range of parameters, so that the model is free of acausality problems. This observation suggests that the relativistic viscoelastic model with such parameters can be regarded as a causal completion of relativistic Navier-Stokes fluid mechanics. By adjusting parameters to various values, this theory can treat a wide variety of materials including elastic materials, Maxwell materials, Kelvin-Voigt materials, and (a nonlinearly generalized version of) simplified Israel-Stewart fluids, and thus we expect the theory to be the most universal description of single-component relativistic continuum materials. We also show that the presence of strains and the corresponding change in temperature are naturally unified through the Tolman law in a generally covariant description of continuum mechanics.

  3. Drinking Water Problems: Copper†

    E-Print Network [OSTI]

    Dozier, Monty; McFarland, Mark L.; Lesikar, Bruce J.

    2006-01-25

    High levels of copper in drinking water can cause health problems. This publication explains the effects of copper in water and methods of removing it. 4 pp....

  4. Sandia National Laboratories Problem

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Problem Natural disasters such as Hurricane Katrina in New Orleans and the tsunami in Japan in 2011 create emergency situations that must be dealt with quickly and...

  5. Transdimensional Approaches to Geophysical Inverse Problems

    E-Print Network [OSTI]

    Bodin, Thomas

    complicated and quantitative mechanisms with simple qualitative concepts. This research was supported underTransdimensional Approaches to Geophysical Inverse Problems Thomas Bodin October 2010 A thesis Except where otherwise indicated in the text, the research described in this thesis is my own original

  6. Sitnikov problem as a source of jets

    E-Print Network [OSTI]

    Marcin Misiak

    2011-08-26

    Sitnikov problem, consisting two close binaries and a third small body is considered, leading to a rapid ejection of the small body from the binaries. This mechanism is proposed as an explanation of jets in many astrophysical systems. Choosing appropriate initial condition relativistic final velocities can be achieved.

  7. An internal seal for repairing natural gas mains

    E-Print Network [OSTI]

    Cooper, Samuel A.

    1984-01-01

    Joint leakage from low pressure natural gas distribution mains (typical value: 0.25 ft[superscript 3] at 6 inwg gas pressure) is a persistent source of maintenance problems for utitlites. External encapsulation is the usual ...

  8. PROBLEM OF THE WEEK

    E-Print Network [OSTI]

    1910-51-11

    Dec 12, 2005 ... COPIES ARE AVAILABLE IN THE MATH LIBRARY. PROBLEM OF THE ... B. 1. C. 1 coincide; and subject to (1) and (2), ?A. 1. B ... PROBLEM OF THE WEEK, 8th Floor, Math Sciences Bldg., Purdue Univ.,. 150 North University†...

  9. Problem planowania paintednot painted

    E-Print Network [OSTI]

    Wojna, Arkadiusz

    ňřōŔ ř“ Ń“ō – “ ň›◊ō —› ”÷ ř »– “”Ř “ »– “”Ř “ Ĺ #12;Problem planowania paintednot painted ceiling ? ceiling »– “”Ř “ ĺ #12;Problem planowania stir-paint not painted ceiling ceiling paintedpaint ceiling get-paint get-ladder mount-ladder »– “”Ř “ Ņ #12;Jezyk STRIPS: stany   ‘÷ ř “ōŔ Ř –”Ř ◊ō “› ”‘

  10. Mechanisms of radiation-induced neoplastic cell transformation

    SciTech Connect (OSTI)

    Yang, T.C.H.; Tobias, C.A.

    1984-04-01

    Studies with cultured mammalian cells demonstrated clearly that radiation can transform cells directly and can enhance the cell transformation by oncogenic DNA viruses. In general, high-LET heavy-ion radiation can be more effective than X and gamma rays in inducing neoplastic cell transformation. Various experimental results indicate that radiation-induced DNA damage, most likely double-strand breaks, is important for both the initiation of cell transformation and for the enhancement of viral transformation. Some of the transformation and enhancement lesions can be repaired properly in the cell, and the amount of irrepairable lesions produced by a given dose depends on the quality of radiation. An inhibition of repair processes with chemical agents can increase the transformation frequency of cells exposed to radiation and/or oncogenic viruses, suggesting that repair mechanisms may play an important role in the radiation transformation. The progression of radiation-transformed cells appears to be a long and complicated process that can be modulated by some nonmutagenic chemical agents, e.g., DMSO. Normal cells can inhibit the expression of transforming properties of tumorigenic cells through an as yet unknown mechanism. The progression and expression of transformation may involve some epigenetic changes in the irradiated cells. 38 references, 15 figures, 1 table.

  11. The Guderley problem revisited

    SciTech Connect (OSTI)

    Ramsey, Scott D [Los Alamos National Laboratory; Kamm, James R [Los Alamos National Laboratory; Bolstad, John H [NON LANL

    2009-01-01

    The self-similar converging-diverging shock wave problem introduced by Guderley in 1942 has been the source of numerous investigations since its publication. In this paper, we review the simplifications and group invariance properties that lead to a self-similar formulation of this problem from the compressible flow equations for a polytropic gas. The complete solution to the self-similar problem reduces to two coupled nonlinear eigenvalue problems: the eigenvalue of the first is the so-called similarity exponent for the converging flow, and that of the second is a trajectory multiplier for the diverging regime. We provide a clear exposition concerning the reflected shock configuration. Additionally, we introduce a new approximation for the similarity exponent, which we compare with other estimates and numerically computed values. Lastly, we use the Guderley problem as the basis of a quantitative verification analysis of a cell-centered, finite volume, Eulerian compressible flow algorithm.

  12. Do VFD Energy Savings Outweigh Potential Mechanical Problems?†

    E-Print Network [OSTI]

    Martin, V.

    1999-01-01

    The use of Variable Frequency Drives (VFD's) for controlling rotating machinery has become relatively commonplace over the past ten to fifteen years. This sudden increase can be attributed to considerable strides in the development and reliability...

  13. The Problem of Motion: The Statistical Mechanics of Zitterbewegung

    E-Print Network [OSTI]

    Kevin H. Knuth

    2014-12-19

    Around 1930, both Gregory Breit and Erwin Schroedinger showed that the eigenvalues of the velocity of a particle described by wavepacket solutions to the Dirac equation are simply $\\pm$c, the speed of light. This led Schroedinger to coin the term Zitterbewegung, which is German for "trembling motion", where all particles of matter (fermions) zig-zag back-and-forth at only the speed of light. The result is that any finite speed less than $c$, including the state of rest, only makes sense as a long-term average that can be thought of as a drift velocity. In this paper, we seriously consider this idea that the observed velocities of particles are time-averages of motion at the speed of light and demonstrate how the relativistic velocity addition rule in one spatial dimension is readily derived by considering the probabilities that a particle is observed to move either to the left or to the right at the speed of light.

  14. Economic penalties of problems and errors in solar energy systems

    SciTech Connect (OSTI)

    Raman, K.; Sparkes, H.R.

    1983-01-01

    Experience with a large number of installed solar energy systems in the HUD Solar Program has shown that a variety of problems and design/installation errors have occurred in many solar systems, sometimes resulting in substantial additional costs for repair and/or replacement. In this paper, the effect of problems and errors on the economics of solar energy systems is examined. A method is outlined for doing this in terms of selected economic indicators. The method is illustrated by a simple example of a residential solar DHW system. An example of an installed, instrumented solar energy system in the HUD Solar Program is then discussed. Detailed results are given for the effects of the problems and errors on the cash flow, cost of delivered heat, discounted payback period, and life-cycle cost of the solar energy system. Conclusions are drawn regarding the most suitable economic indicators for showing the effects of problems and errors in solar energy systems. A method is outlined for deciding on the maximum justifiable expenditure for maintenance on a solar energy system with problems or errors.

  15. Essays on dynamic games and mechanism design

    E-Print Network [OSTI]

    Lang, Ruitian

    2014-01-01

    The dissertation considers three topics in dynamic games and mechanism design. In both problems, asymmetric information causes inefficiency in production and allocation. The first chapter considers the inefficiency from ...

  16. Relocation and repair of the National Geotechnical Centrifuge. Final report

    SciTech Connect (OSTI)

    Cheney, J.A.

    1994-10-01

    In January of 1984, the large geotechnical centrifuge located at NASA Ames Research Center, was in the first stages of operational checkout when the main thrust bearing of the large D.C. drive motor failed. After many months of investigation and proposals for repair of the facility, it became evident that it would be far more advantageous to the engineering community to remove those components of the centrifuge that were undamaged to the Davis campus and replace the drive system completely. The large centrifuge had cost over 2 million dollars to build, and it would have been irresponsible to simply scrap it. Recognizing this fact, funds were solicited and received from various sources, and Beam Engineering Inc. was contracted to design and construct the centrifuge at its new location. The University of California contributed a quarter of a million dollars and Tyndall Air Force Base, through Los Alamos National Laboratory, contributed $140,000. There were funds also contributed by LANL, LLNL, US Navy and NSF. The first stage in the phased development of the newly located centrifuge is nearing completion, which prompts the writing of this report. By the time that this report reaches the reader the first runs of the centrifuge will have been completed. The present report describes the present capability of the centrifuge and the plans for upgrading as time goes on. Several pilot studies were carried out. The experiments involved (1) the effects of nearby explosions on buried thin walled containers and (2) the advection and dispersion of toxic waste water through soils.

  17. DNA repair decline during mouse spermiogenesis results in the accumulation of heritable DNA damage

    SciTech Connect (OSTI)

    Marchetti, Francesco; Marchetti, Francesco; Wryobek, Andrew J

    2008-02-21

    The post-meiotic phase of mouse spermatogenesis (spermiogenesis) is very sensitive to the genomic effects of environmental mutagens because as male germ cells form mature sperm they progressively lose the ability to repair DNA damage. We hypothesized that repeated exposures to mutagens during this repair-deficient phase result in the accumulation of heritable genomic damage in mouse sperm that leads to chromosomal aberrations in zygotes after fertilization. We used a combination of single or fractionated exposures to diepoxybutane (DEB), a component of tobacco smoke, to investigate how differential DNA repair efficiencies during the three weeks of spermiogenesis affected the accumulation of DEB-induced heritable damage in early spermatids (21-15 days before fertilization, dbf), late spermatids (14-8 dbf) and sperm (7- 1 dbf). Analysis of chromosomalaberrations in zygotic metaphases using PAINT/DAPI showed that late spermatids and sperm are unable to repair DEB-induced DNA damage as demonstrated by significant increases (P<0.001) in the frequencies of zygotes with chromosomal aberrations. Comparisons between single and fractionated exposures suggested that the DNA repair-deficient window during late spermiogenesis may be less than two weeks in the mouse and that during this repair-deficient window there is accumulation of DNA damage in sperm. Finally, the dose-response study in sperm indicated a linear response for both single and repeated exposures. These findings show that the differential DNA repair capacity of post-meioitic male germ cells has a major impact on the risk of paternally transmitted heritable damage and suggest that chronic exposures that may occur in the weeks prior to fertilization because of occupational or lifestyle factors (i.e, smoking) can lead to an accumulation of genetic damage in sperm and result in heritable chromosomal aberrations of paternal origin.

  18. DNA Repair Decline During Mouse Spermiogenesis Results in the Accumulation of Heritable DNA Damage

    SciTech Connect (OSTI)

    Marchetti, Francesco; Marchetti, Francesco; Wyrobek, Andrew J.

    2007-12-01

    The post-meiotic phase of mouse spermatogenesis (spermiogenesis) is very sensitive to the genomic effects of environmental mutagens because as male germ cells form mature sperm they progressively lose the ability to repair DNA damage. We hypothesized that repeated exposures to mutagens during this repair-deficient phase result in the accumulation of heritable genomic damage in mouse sperm that leads to chromosomal aberrations in zygotes after fertilization. We used a combination of single or fractionated exposures to diepoxybutane (DEB), a component of tobacco smoke, to investigate how differential DNA repair efficiencies during the three weeks of spermiogenesis affected the accumulation of DEB-induced heritable damage in early spermatids (21-15 days before fertilization, dbf), late spermatids (14-8 dbf) and sperm (7-1 dbf). Analysis of chromosomal aberrations in zygotic metaphases using PAINT/DAPI showed that late spermatids and sperm are unable to repair DEB-induced DNA damage as demonstrated by significant increases (P<0.001) in the frequencies of zygotes with chromosomal aberrations. Comparisons between single and fractionated exposures suggested that the DNA repair-deficient window during late spermiogenesis may be less than two weeks in the mouse and that during this repair-deficient window there is accumulation of DNA damage in sperm. Finally, the dose-response study in sperm indicated a linear response for both single and repeated exposures. These findings show that the differential DNA repair capacity of post-meioitic male germ cells has a major impact on the risk of paternally transmitted heritable damage and suggest that chronic exposures that may occur in the weeks prior to fertilization because of occupational or lifestyle factors (i.e, smoking) can lead to an accumulation of genetic damage in sperm and result in heritable chromosomal aberrations of paternal origin.

  19. Fractofusion mechanism

    SciTech Connect (OSTI)

    Yasui, K. . Dept. of Physics)

    1992-11-01

    In this paper, the fractofusion mechanism of cold fusion is investigated theoretically. The conditions necessary for fractofusion during the absorption of deuterium atoms by palladium specimens (the condition of so-called cold fusion experiments) is clarified, including crack generation at grain boundaries, the high orientation angle of grains, rapid crack formation, the increase of electrical resistance around a crack, the large width of cracks, and the generation of many cracks. The origin and quantity of the electrical field inside cracks in the conductor are also clarified. By the fractofusion mechanism, the experimental facts that neutron emissions are observed in bursts, that sometimes they coincide with the deformation of a palladium specimen, and that in many experiments excess neutrons were not observed are qualitatively explained. The upper limit of the total fractofusion yields during the absorption of deuterium atoms by palladium specimens are estimated.

  20. Jon Petersen1, Shea Dillon2 1B.S., Mechanical & Materials Engineering,2 B.S., Mechanical & Materials Engineering

    E-Print Network [OSTI]

    Bertini, Robert L.

    Jon Petersen1, Shea Dillon2 1B.S., Mechanical & Materials Engineering,2 B.S., Mechanical & Materials Engineering PROBLEM/OPPORTUNITY Figure 2: Live, unfiltered accelerometer/gyroscope data from

  1. Linear Programming brewer's problem

    E-Print Network [OSTI]

    Sedgewick, Robert

    : Brewer's problem Small brewery produces ale and beer. ∑ Production limited by scarce resources: corn A 0 B 0 Small brewery produces ale and beer. ∑ Production limited by scarce resources: corn, hops

  2. Avoiding Calving Problems

    E-Print Network [OSTI]

    Sprott, L. R.

    1998-03-12

    Calving difficulty, or dystocia, is influenced largely by genetics and the age of the dam. The main cause of calving problems is heavy birthweight. Solutions include selecting the right bull and mating it to properly developed heifers....

  3. (ADMM): quadratic problems

    E-Print Network [OSTI]

    2014-12-11

    the step-size parameter for quadratic programing problems. ... We denote the set of real numbers with R and define the set of positive (nonnegative) real numbers as R++ .... where ? > 0 are abound in statistics, machine learning, and control.

  4. The Universal Kepler Problem

    E-Print Network [OSTI]

    Guowu Meng

    2014-12-04

    For each simple euclidean Jordan algebra $V$, we introduce the analogue of hamiltonian, angular momentum and Laplace-Runge-Lenz vector in the Kepler problem. Being referred to as the universal hamiltonian, universal angular momentum and universal Laplace-Runge-Lenz vector respectively, they are elements in (essentially) the TKK (Tits-Kantor-Koecher) algebra of $V$ and satisfy commutation relations similar to the ones for the hamiltonian, angular momentum and Laplace-Runge-Lenz vector in the Kepler problem. We also give some examples of Poisson realization of the TKK algebra, along with the resulting classical generalized Kepler problems. For the simplest simple euclidean Jordan algebra (i.e., $\\mathbb R$), we give examples of operator realization for the TKK algebra, along with the resulting quantum generalized Kepler problems.

  5. Pauli problem in thermodynamics

    E-Print Network [OSTI]

    Artur E. Ruuge

    2013-08-01

    A thermodynamic analogue of the Pauli problem (reconstruction of a wavefunction from the position and momentum distributions) is formulated. The coordinates of a quantum system are replaced by the inverse absolute temperature and other intensive quantities, and the Planck constant is replaced by the Boltzmann constant multiplied by two. A new natural mathematical generalization of the quasithermodynamic fluctuation theory is suggested and sufficient conditions for the existence of asymptotic solutions of the thermodynamic Pauli problem are obtained.

  6. The role of mismatch repair in mediating cellular sensitivity to cisplatin : the Escherichia coli methyl-directed repair paradigm

    E-Print Network [OSTI]

    Robbins, Jennifer L

    2006-01-01

    The anticancer drug cisplatin is in widespread use but its mechanism of action is only poorly understood. Moreover, human cancers acquire resistance to the drug, which limits its clinical utility. A paradox in the field ...

  7. Knowledge activation and organization in physics problem-solving Mel Sabella

    E-Print Network [OSTI]

    Maryland at College Park, University of

    Knowledge activation and organization in physics problem-solving Mel Sabella Department of student problem-solving behavior on a mechanics task that integrates the concepts of force, mo- tion physics need to learn in order to solve problems. They need to be able to make sense of what the problem

  8. AKS systems and Lepage equivalent problems

    E-Print Network [OSTI]

    Santiago Capriotti

    2011-01-06

    The integrable systems known as "AKS systems" admit a natural formulation in terms of a Hamiltonian picture. The Lagrangian side of these systems are far less known; a version in these terms can be found in a work of Feher et al. The purpose of these notes in to provide a novel description of AKS systems in terms of a variational problem different from the usual in mechanics. Additionally, and using techniques borrowed from an article of M. Gotay, it was possible to build the Hamiltonian side of this variational problem, allowing us to establish the equivalence with the usual approach to these integrable systems.

  9. Learning ProblemSolving Concepts by Reflecting on Problem Solving

    E-Print Network [OSTI]

    Goel, Ashok

    Learning Problem≠Solving Concepts by Reflecting on Problem Solving Eleni Stroulia and Ashok K. Goel Learning and problem solving are intimately related: problem solving determines the knowledge requirements of the reasoner which learning must fulfill, and learning enables improved problem≠solving performance. Different

  10. Problem Solving 1 Polya's Four Phases of Problem Solving

    E-Print Network [OSTI]

    Lee, Carl

    Problem Solving 1 Polya's Four Phases of Problem Solving The following comes from the famous book by George Polya called How to Solve It. 1. Understanding the Problem. You have to understand the problem restate it still differently? Go back to definitions. If you cannot solve the proposed problem try

  11. Resource constrained scheduling problem at U.S. Naval Shipyards

    E-Print Network [OSTI]

    Nawara, Terrence M. (Terrence Michael)

    2013-01-01

    Submarine repair schedules are some of the most complex schedules seen in project management. Repairs of a nuclear U.S. submarine are resource constrained since resources are divided among approximately thirty shops (e.g. ...

  12. Quantization of Minimal Strings: a Mechanical Analog

    SciTech Connect (OSTI)

    Gomez, Cesar; Montanez, Sergio; Resco, Pedro [Instituto de Fisica Teorica CSIC/UAM, C-XVI Universidad Autonoma, E-28049 Madrid (Spain)

    2006-06-19

    Recent progress in the study of Liouville field theory opens the possibility to address some problems of quantum gravity using minimal strings as a theoretical laboratory. We present a procedure to embed the minimal string target space into the phase space of an associated mechanical system. By this map quantum effects on the target space correspond to quantum corrections on the mechanical model.

  13. Faculty of Engineering Mechanical, Automotive and

    E-Print Network [OSTI]

    Faculty of Engineering Mechanical, Automotive and Materials Engineering The field of Mechanical Engineering includes two broad areas of study. The first involves heat and power, and is referred, Automotive and Materials Engineering offers a multi-faceted program where you tackle real-world problems

  14. Direct mechanism in solar nuclear reactions

    E-Print Network [OSTI]

    H. Oberhummer; G. Staudt

    1994-04-22

    A short overview of the direct reaction mechanism and the models used for the analysis of such processes is given. Nuclear reactions proceeding through the direct mechanism and involved in solar hydrogen burning are discussed. The significance of these nuclear reactions with respect to the solar neutrino problem is investigated.

  15. Automatic coke oven heating control system at Burns Harbor for normal and repair operation

    SciTech Connect (OSTI)

    Battle, E.T.; Chen, K.L. [Bethlehem Steel Corp., Burns Harbor, IN (United States); [Bethlehem Steel Corp., PA (United States)

    1997-12-31

    An automatic heating control system for coke oven batteries was developed in 1985 for the Burns Harbor No. 1 battery and reported in the 1989 Ironmaking Conference Proceedings. The original system was designed to maintain a target coke temperature at a given production level under normal operating conditions. Since 1989, enhancements have been made to this control system so that it can also control the battery heating when the battery is under repair. The new control system has improved heating control capability because it adjusts the heat input to the battery in response to anticipated changes in the production schedule. During a recent repair of this 82 oven battery, the pushing schedule changed from 102 ovens/day to 88 ovens/day, then back to 102 ovens/day, then to 107 ovens/day. During this repair, the control system was able to maintain the coke temperature average standard deviation at 44 F, with a maximum 75 F.

  16. A survey of repair practices for nuclear power plant containment metallic pressure boundaries

    SciTech Connect (OSTI)

    Oland, C.B.; Naus, D.J.

    1998-05-01

    The Nuclear Regulatory Commission has initiated a program at the Oak Ridge National Laboratory to provide assistance in their assessment of the effects of potential degradation on the structural integrity and leaktightness of metal containment vessels and steel liners of concrete containments in nuclear power plants. One of the program objectives is to identify repair practices for restoring metallic containment pressure boundary components that have been damaged or degraded in service. This report presents issues associated with inservice condition assessments and continued service evaluations and identifies the rules and requirements for the repair and replacement of nonconforming containment pressure boundary components by welding or metal removal. Discussion topics include base and welding materials, welding procedure and performance qualifications, inspection techniques, testing methods, acceptance criteria, and documentation requirements necessary for making acceptable repairs and replacements so that the plant can be returned to a safe operating condition.

  17. Evaluation of bisphenol E cyanate ester for the resin-injection repair of advanced composites

    SciTech Connect (OSTI)

    Wilber Yaote Lio

    2009-12-19

    This thesis is a compilation of a general introduction and literature review that ties together the subsequent chapters which consist of two journal articles that have yet to be submitted for publication. The overall topic relates to the evaluation and application of a new class of cyanate ester resin with unique properties that lend it applicable to use as a resin for injection repair of high glass transition temperature polymer matrix composites. The first article (Chapter 2) details the evaluation and optimization of adhesive properties of this cyanate ester and alumina nanocomposites under different conditions. The second article (Chapter 3) describes the development and evaluation of an injection repair system for repairing delaminations in polymer matrix composites.

  18. Analytical solutions to matrix diffusion problems

    SciTech Connect (OSTI)

    Kekšlšinen, Pekka

    2014-10-06

    We report an analytical method to solve in a few cases of practical interest the equations which have traditionally been proposed for the matrix diffusion problem. In matrix diffusion, elements dissolved in ground water can penetrate the porous rock surronuding the advective flow paths. In the context of radioactive waste repositories this phenomenon provides a mechanism by which the area of rock surface in contact with advecting elements is greatly enhanced, and can thus be an important delay mechanism. The cases solved are relevant for laboratory as well for in situ experiments. Solutions are given as integral representations well suited for easy numerical solution.

  19. Hard (State) Problems

    E-Print Network [OSTI]

    John A. Tomsick

    2008-12-16

    For microquasars, the one time when these systems exhibit steady and powerful jets is when they are in the hard state. Thus, our understanding of this state is key to learning about the disk/jet connection. Recent observational and theoretical results have led to questions about whether we really understand the physical properties of this state, and even our basic picture of this state is uncertain. Here, I discuss some of the recent developments and possible problems with our understanding of this state. Overall, it appears that the strongest challenge to the standard truncated disk picture is the detection of broad iron features in the X-ray spectra, and it seems that either there is a problem with the truncated disk picture or there is a problem with the relativistic reflection models used to explain the broad iron features.

  20. Sign problem and MEM

    E-Print Network [OSTI]

    Masahiro Imachi; Yasuhiko Shinno; Hiroshi Yoneyama

    2006-01-13

    The sign problem is notorious in Monte Carlo simulations of lattice QCD with the finite density, lattice field theory (LFT) with a $\\theta$ term and quantum spin models. In this report, to deal with the sign problem, we apply the maximum entropy method (MEM) to LFT with the $\\theta$ term and investigate to what extent the MEM is applicable to this issue. Based on this study, we also make a brief comment about lattice QCD with the finite density in terms of the MEM.

  1. Mechanical & Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical & Aerospace Engineering An experimental methodology is presented for mechanism verification of physics-based prognosis of mechanical damage, such as fatigue. The proposed experimental methodology includes multi-resolution in-situ mechanical testing, advanced imaging analysis, and mechanism

  2. Bosh repairs No. 3 blast furnace, Edgar Thomson Plant Mon Valley Works

    SciTech Connect (OSTI)

    Stoupis, M.G.

    1993-01-01

    The paper describes in detail the steps taken from quenching to dry out of the furnace to repair the bosh area of the No.3 blast furnace. Inspection of the area revealed that there was no brick anywhere in the bosh. Brick in the tuyere breast area had been peeled back to reveal the steel plate, and descaling revealed 14 pipes fully exposed. None were leaking, but one seemed badly deteriorated. Conventional repairs could not take place before the scheduled blow-in. Installation of coolers were instead tried.

  3. Mitral Web -A New Concept for Mitral Valve Repair: Improved Engineering Design and In-Vitro Studies

    E-Print Network [OSTI]

    Pekkan, Kerem

    Mitral Web - A New Concept for Mitral Valve Repair: Improved Engineering Design and In of Biomedical Engineering, Georgia Institute of Technology, GA, USA Myxomatous mitral valve disease is currently reported that mitral valve repair is preferable to valve replace- ment, as it offers certain advantages

  4. Restoration and repair of 30-year old cooling towers at the Paducah Gaseous Diffusion Plant, Phase I. Draft 1

    SciTech Connect (OSTI)

    Shelton, M.F.

    1985-01-01

    Early in 1980, a comprehensive reliability study was made to ascertain the ability of the present 30-year old recirculating water system to meet the anticipated load demand through the year 2000. The findings and recommendations of this study were used as a guide to schedule uprating and repairs. This paper deals with the underground distribution system and cooling tower repairs.

  5. Mechanical Buckling: Mechanics, Metrology, and Stretchable Electronics

    E-Print Network [OSTI]

    Rogers, John A.

    Mechanical Buckling: Mechanics, Metrology, and Stretchable Electronics By Dahl-Young Khang, John A of wrinkling is in aging human skin. All such phenomena originate from the same mechanism, i.e., mechanical of the wave, or their wavelength, depends upon the film thickness and/or mechanical properties of materials

  6. Introduction Optimal Control Problem

    E-Print Network [OSTI]

    Grigorieva, Ellina V.

    and Computational Simulations Ellina Grigorieva and Evgenii Khailov Optimal control of a waste water cleaning plant Khailov Optimal control of a waste water cleaning plant #12;Introduction Model Optimal Control Problem applications will be discussed. Ellina Grigorieva and Evgenii Khailov Optimal control of a waste water cleaning

  7. Drinking Water Problems: Corrosion

    E-Print Network [OSTI]

    valves and other water control surfaces, creating leaks inside and outside of valves and faucetsDrinking Water Problems: Corrosion Mark L. McFarland, Tony L. Provin, and Diane E. Boellstorff* Professor and Extension Water Quality Coordinator, Professor and Extension Water Testing Laboratory Director

  8. Dynamical impurity problems

    SciTech Connect (OSTI)

    Emery, V.J. [Brookhaven National Lab., Upton, NY (United States); Kivelson, S.A. [California Univ., Los Angeles, CA (United States). Dept. of Physics

    1993-12-31

    In the past few years there has been a resurgence of interest in dynamical impurity problems, as a result of developments in the theory of correlated electron systems. The general dynamical impurity problem is a set of conduction electrons interacting with an impurity which has internal degrees of freedom. The simplest and earliest example, the Kondo problem, has attracted interest since the mid-sixties not only because of its physical importance but also as an example of a model displaying logarithmic divergences order by order in perturbation theory. It provided one of the earliest applications of the renormalization group method, which is designed to deal with just such a situation. As we shall see, the antiferromagnetic Kondo model is controlled by a strong-coupling fixed point, and the essence of the renormalization group solution is to carry out the global renormalization numerically starting from the original (weak-coupling) Hamiltonian. In these lectures, we shall describe an alternative route in which we identify an exactly solvable model which renormalizes to the same fixed point as the original dynamical impurity problem. This approach is akin to determining the critical behavior at a second order phase transition point by solving any model in a given universality class.

  9. Prisoner Problems Tyler Seacrest

    E-Print Network [OSTI]

    Marley, Tom

    Prisoner Problems Tyler Seacrest University of Nebraska-Lincoln December 3, 2010 #12;The Setup #12;The Setup One day, when the warden of Puzzlania maximum security prison is bored, he decides to subject all his prisoners to a devious mathematical game. They are free to discuss strategy beforehand

  10. Problems in Engineering and

    E-Print Network [OSTI]

    Eagar, Thomas W.

    Problems in Engineering and Science Education Why Do We Have a Weakness in Materials Synthesis, Materials Science and Engineering in the 1990s: Maintaining Competitiveness in the Age of Materials science and engi- neering alone; it is symptomatic of the way we teach all science and engineering. We

  11. Hot repair of ceramic burner on hot blast stoves at USS/Kobe`s {number_sign}3 blast furnace

    SciTech Connect (OSTI)

    Bernarding, T.F.; Chemorov, M.; Shimono, S.; Phillips, G.R.

    1997-12-31

    During the 1992 reline of the No. 3 blast furnace, three new stoves were constructed. The design of the stoves, equipped with internal ceramic burners, was for providing a hot blast temperature of 2,000 F at a wind rate of 140,000 SCFM. After 3 years the performance had deteriorated so the burners were cleaned. When a second cleaning did not improve the performance of No. 3 blast furnace, it was decided to repair the refractory while still hot. The paper describes the hot repair procedures, taking a stove off for repairs, maintenance heat up during repairs, two stove operation, stove commissioning, repair of a ceramic burner, and wet gas prevention.

  12. Problem Solving 401, Spring 1997

    E-Print Network [OSTI]

    Reserve: G. Polya, How to Solve it. GRADING POLICY: The grading system is designed to foster habits which aid in problem solving. Suppose a problem is†...

  13. SEACAS Theory Manuals: Part II. Nonlinear Continuum Mechanics

    SciTech Connect (OSTI)

    Attaway, S.W.; Laursen, T.A.; Zadoks, R.I.

    1998-09-01

    This report summarizes the key continuum mechanics concepts required for the systematic prescription and numerical solution of finite deformation solid mechanics problems. Topics surveyed include measures of deformation appropriate for media undergoing large deformations, stress measures appropriate for such problems, balance laws and their role in nonlinear continuum mechanics, the role of frame indifference in description of large deformation response, and the extension of these theories to encompass two dimensional idealizations, structural idealizations, and rigid body behavior. There are three companion reports that describe the problem formulation, constitutive modeling, and finite element technology for nonlinear continuum mechanics systems.

  14. Dependability Modelling of Repairable Systems using Bayesian Networks Martin Neil *, David Marquez**

    E-Print Network [OSTI]

    Neil, Martin

    : We present a Hybrid Bayesian Network (HBN) framework to model the availability of renewable systems repair (renewal) distributions might be modelled using HBNs. Keywords: Bayesian Networks; Bayesian systems represented by a series of models each designed to model distinct stages in the renewal process

  15. Development/Plasticity/Repair The Bone Morphogenetic Protein Roof Plate Chemorepellent

    E-Print Network [OSTI]

    Butler, Samantha

    Development/Plasticity/Repair The Bone Morphogenetic Protein Roof Plate Chemorepellent Regulates, Toronto, Ontario, Canada M5G 1X8 Commissural spinal axons extend away from the roof plate (RP) in response to the dorsal midline and are generated by the bone morphogenetic proteins (BMPs) in the roof plate (RP) (Liem

  16. Model Repair --Aligning Process Models to Reality Dirk Fahland, Wil M.P. van der Aalst

    E-Print Network [OSTI]

    van der Aalst, Wil

    discovery and (2) conformance checking. Process discovery techniques automatically construct a process model an existing process model does not conform to reality one could -- in principle -- use process discoveryModel Repair -- Aligning Process Models to Reality Dirk Fahland, Wil M.P. van der Aalst Eindhoven

  17. FFaacciilliittiieess MMaannaaggeemmeenntt//EEnnvviirroonnmmeennttaall HHeeaalltthh && SSaaffeettyy Hazardous Work Area/Equipment Repair Form

    E-Print Network [OSTI]

    Mojzsis, Stephen J.

    Hazardous Work Area/Equipment Repair Form Form Instructions: Client is responsible for completing this form to assure that equipment and/or immediate work areas are not contaminated with any hazardous materials, tissue, etc.) Do Safety Hazards exist in the work area? N ___ Y ___ (Electrical, burn, or trip hazards

  18. Development/Plasticity/Repair Dendritic Spine Dynamics Regulate the Long-Term Stability

    E-Print Network [OSTI]

    van Rossum, Mark

    Development/Plasticity/Repair Dendritic Spine Dynamics Regulate the Long-Term Stability of Synaptic Plasticity Cian O'Donnell,1,2 Matthew F. Nolan,3 and Mark C. W. van Rossum1 1Institute for Adaptive of Edinburgh, Edinburgh EH8 9XD, United Kingdom Long-term synaptic plasticity requires postsynaptic influx

  19. Development/Plasticity/Repair Dendritic BDNF Synthesis Is Required for Late-Phase Spine

    E-Print Network [OSTI]

    Stryker, Michael

    Development/Plasticity/Repair Dendritic BDNF Synthesis Is Required for Late-Phase Spine Maturation paradigm for experience-dependent cortical development is called ocular dominance (OD) plasticity, where closing one eye for a few days during a critical period of heightened plasticity leads to marked decrease

  20. Development/Plasticity/Repair Wiring Stability of the Adult Drosophila Olfactory Circuit

    E-Print Network [OSTI]

    Luo, Liqun

    Development/Plasticity/Repair Wiring Stability of the Adult Drosophila Olfactory Circuit after Institute of Molecular Pathology, 1030 Vienna, Austria Neuronal wiring plasticity in response to experience. Here, we assess wiring plasticity in a discrete neural map represented by the adult Drosophila

  1. Development/Plasticity/Repair Dark Exposure Extends the Integration Window for

    E-Print Network [OSTI]

    Lee, Hey-Kyoung

    Development/Plasticity/Repair Dark Exposure Extends the Integration Window for Spike-Timing-Dependent Plasticity Yatu Guo,1,2 Shiyong Huang,1 Roberto de Pasquale,1 Kevin McGehrin,4 Hey-Kyoung Lee,1,3,4 Kanxing-timing-dependent plasticity, in which the polarity of plasticity is determined not by the stimulationfrequency

  2. Development/Plasticity/Repair Simultaneous NMDA-Dependent Long-Term Potentiation of

    E-Print Network [OSTI]

    Segal, Menahem

    Development/Plasticity/Repair Simultaneous NMDA-Dependent Long-Term Potentiation of EPSCs and Long activity-dependent long-term plasticity of neuronal networks is the interplay between excitatory, whereas a nitric oxide synthase inhibitor was ineffec- tive. Finally, network-induced plasticity

  3. Toward a State of Good Repair for Railroad Bridges through Structural Health Monitoring

    E-Print Network [OSTI]

    Bustamante, FabiŠn E.

    Toward a State of Good Repair for Railroad Bridges through Structural Health Monitoring NUTC of this research is to add a new tool to the asset management toolbox: structural health monitoring, particularly is Structural Health Monitoring (SHM)? SHM is process of intelligently collecting data from sensors on critical

  4. Multilayer sulfur-resistant composite metal membranes and methods of making and repairing the same

    DOE Patents [OSTI]

    Way, J. Douglas; Hatlevik, Oyvind

    2014-07-15

    The invention relates to thin, hydrogen-permeable, sulfur-resistant membranes formed from multi-layers of palladium or palladium-alloy coatings on porous, ceramic or metal supports, methods of making these membranes, methods of repairing layers of these membranes and devices that incorporate these membranes.

  5. Development/Plasticity/Repair The ERK2 Mitogen-Activated Protein Kinase Regulates the

    E-Print Network [OSTI]

    Development/Plasticity/Repair The ERK2 Mitogen-Activated Protein Kinase Regulates the Timing Oligodendrocytedevelopmentistightlycontrolledbyavarietyofextracellulargrowthanddifferentiationfactors.Themitogen-activated protein kinases (MAPKs), ERK1 and ERK2, are critical intracellular signaling (ERKs) are ubiquitously expressed, coordinately regulated, and highly similar, but Erk2 deletion in mice

  6. Development/Plasticity/Repair Phosphatidylinositol 3-Kinase Activates ERK in Primary

    E-Print Network [OSTI]

    Clapham, David E.

    Development/Plasticity/Repair Phosphatidylinositol 3-Kinase Activates ERK in Primary Sensory activation to inflammatory pain. We further investigated the correlationbetweenthePI3KandtheERK294002 and wortmannin, indicative of the activation of PI3K by both agents. ERK activation by capsaicin

  7. Is the Cure Worse Than the Disease? Overfitting in Automated Program Repair

    E-Print Network [OSTI]

    Brun, Yuriy

    Is the Cure Worse Than the Disease? Overfitting in Automated Program Repair Edward K. Smith Earl T techniques validate patch correctness with respect to user-provided or inferred contracts [24 undertested functionality. Permission to make digital or hard copies of all or part of this work for personal

  8. Is the Cure Worse Than the Disease? Overfitting in Automated Program Repair

    E-Print Network [OSTI]

    Fernandez, Thomas

    Is the Cure Worse Than the Disease? Overfitting in Automated Program Repair Edward K. Smith Earl T-provided or inferred contracts [26,46,60], a larger proportion use test cases. Permission to make digital or hard copies of all or part of this work for personal or classroom use is granted without fee provided

  9. Metal inhibition of human alkylpurine-DNA-N-glycosylase activity in base excision repair

    E-Print Network [OSTI]

    Wang, Ping; Guliaev, Anton B.; Hang, Bo

    2006-01-01

    0.38 nM ) Zn 2+ Cd 2 + Metal ion (ĶM) Product % Relativeof hAPE1 Zn 2 + Cd 2 + Metal ion (ĶM) Figure 6 Figure 7Interactions by carcinogenic metal compounds with DNA repair

  10. Development/Plasticity/Repair NG2 Glia Generate New Oligodendrocytes But Few

    E-Print Network [OSTI]

    Richardson, William D.

    Development/Plasticity/Repair NG2 Glia Generate New Oligodendrocytes But Few Astrocytes in a Murine-derived growth factor receptor subunit (PDGFRA) and the NG2 proteoglycan. These "NG2 cells" descend from and white matter of the postnatal brain. It has been proposed that NG2 cells can also

  11. A New Rhenanite ( -NaCaPO4) and Hydroxyapatite Biphasic Biomaterial for Skeletal Repair

    E-Print Network [OSTI]

    Tas, A. Cuneyt

    A New Rhenanite ( -NaCaPO4) and Hydroxyapatite Biphasic Biomaterial for Skeletal Repair Sahil Abstract: Biphasic -rhenanite ( -NaCaPO4)≠hydroxyapatite (Ca10(PO4)6(OH)2) biomaterials were prepared% rhenanite) biomaterials, while retaining their submicron particle sizes and high surface areas. -rhenanite

  12. Accepting Failure: Availability through Repair-centric System Design Aaron Brown

    E-Print Network [OSTI]

    California at Berkeley, University of

    1 Accepting Failure: Availability through Repair-centric System Design Aaron Brown Qualifying Exam Proposal 3 April 2001 Abstract Motivated by the lack of rapid improvement in the availability of Internet server systems, we introduce a new philosophy for designing highly-available systems that better reflects

  13. Development/Plasticity/Repair A Specific Requirement of Arc/Arg3.1 for Visual

    E-Print Network [OSTI]

    Lee, Hey-Kyoung

    Development/Plasticity/Repair A Specific Requirement of Arc/Arg3.1 for Visual Experience-Induced Homeostatic Synaptic Plasticity in Mouse Primary Visual Cortex Ming Gao,1 Kenneth Sossa,1 Lihua Song,1 Lauren.OurresultsdemonstratethatArc/Arg3.1playsaselectiveroleinregulatingvisualexperience-dependent homeostatic plasticity of excitatory

  14. Development/Plasticity/Repair Hair Cell Replacement in Adult Mouse Utricles after

    E-Print Network [OSTI]

    Rubel, Edwin

    Development/Plasticity/Repair Hair Cell Replacement in Adult Mouse Utricles after Targeted Ablation of Hair Cells with Diphtheria Toxin Justin S. Golub,1 Ling Tong,1 Tot B. Ngyuen,1 Cliff R. Hume,1 Richard utricle by inserting the human diphtheria toxin receptor (DTR) gene into the Pou4f3 gene, which encodes

  15. Overview of NCHRP Design Guideline for EPS-Block Geofoam in Slope Stabilization and Repair

    E-Print Network [OSTI]

    Manhattan College Bronx, New York 10471 Tel: (718) 826-7177 E-mail: john.horvath@manhattan.edu Dov and repair applications based on the results of National Cooperative Highway Research Program (NCHRP) Project was performed under NCHRP Project 24-11(01) and produced a design guideline for use of EPS blocks in stand

  16. The inhibiting bisection problem.

    SciTech Connect (OSTI)

    Pinar, Ali

    2010-11-01

    Given a graph where each vertex is assigned a generation or consumption volume, we try to bisect the graph so that each part has a significant generation/consumption mismatch, and the cutsize of the bisection is small. Our motivation comes from the vulnerability analysis of distribution systems such as the electric power system. We show that the constrained version of the problem, where we place either the cutsize or the mismatch significance as a constraint and optimize the other, is NP-complete, and provide an integer programming formulation. We also propose an alternative relaxed formulation, which can trade-off between the two objectives and show that the alternative formulation of the problem can be solved in polynomial time by a maximum flow solver. Our experiments with benchmark electric power systems validate the effectiveness of our methods.

  17. MECHANICAL ENGINEERING Curriculum Notes

    E-Print Network [OSTI]

    Mohan, Chilukuri K.

    MECHANICAL ENGINEERING Curriculum Notes 2013-2014 1. Mechanical engineering students must complete of technical electives. 2. Technical electives must be taken within the Mechanical and Aerospace Engineering

  18. Physicalism versus quantum mechanics

    E-Print Network [OSTI]

    Stapp, Henry P; Theoretical Physics Group; Physics Division

    2009-01-01

    Foundations of Quantum Mechanics. (Princeton UniversityMind, Matter, and Quantum Mechanics, (Springer, Berlin & NewMindful Universe: Quantum Mechanics and the Participating

  19. Sandia Energy - Mechanical Testing

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Mechanical Testing Home Stationary Power Nuclear Fuel Cycle Advanced Nuclear Energy Nuclear Energy Systems Laboratory (NESL) Brayton Lab Mechanical Testing Mechanical...

  20. A Problem Generator Jorg Fliege

    E-Print Network [OSTI]

    Fliege, Jörg

    A Problem Generator Jorg Fliege Fachbereich Mathematik Universitat Dortmund 44221 Dortmund;nd a new, previously unconsidered one. We propose a problem generator that can auto- matically generate new optimization problems. These problems can then be analyzed by scientists with, e. g., standard

  1. Investigation into mechanical properties of bone and its main constituents

    E-Print Network [OSTI]

    Evdokimenko, Ekaterina

    2012-01-01

    treatment of intrabony periodontal defects: 6 year resultsbones, to repair periodontal defects, bone removal from

  2. Mechanical and Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical and Aerospace Engineering seminar Three Dimensional Traction Force Microscopy with Applications in Cell Mechanics abstract The interactions between biochemical and mechanical signals during-dimensional measurement techniques are needed to investigate the effect of mechanical properties of the substrate

  3. Research Review Mechanical Engineering

    E-Print Network [OSTI]

    Theune, MariŽt

    Research Review Mechanical Engineering University of Twente #12;QANU / Research Review Mechanical;QANU / Research Review Mechanical Engineering / University of Twente 3 Report on the research assessment of Mechanical Engineering at the University of Twente Contents Preface

  4. Solving the Bargaining Problem

    E-Print Network [OSTI]

    Schellenberg, James A.

    1990-01-01

    of the available utility binot. affect the solution; only the 4. The assumption of Pareto o~~r;:,a~~tyatI~ sh~uld affect the solution. cannot be a solution when there is ∑ s . olds that an outcome of the players could do better and thanothher feasible outcome where... theory of collective bar ~ ~cess-based model, namely in Zeuthen's earlier Harsanyi solution conce~t ~n~fierocesse~d∑ Evden today the .Zeuthen-Nash- n consi ere the appropriate theoretical 80 Solving the Bargaining Problem resolution for the bargaining...

  5. Computational Mechanics manuscript No. (will be inserted by the editor)

    E-Print Network [OSTI]

    Wieners, Christian

    and the application to 3-d simulations of a triphasic porous media model in soil mechanics Christian Wieners1 , Martin a general parallel model for solving coupled nonlinear and time-dependent problems in soil mechanics, where mechanics, where we compute the deformation of unsaturated soil together with the pore-fluid flow of water

  6. Pure Wave Mechanics and the Very Idea of Empirical Adequacy

    E-Print Network [OSTI]

    Stanford, Kyle

    Pure Wave Mechanics and the Very Idea of Empirical Adequacy DRAFT Jeffrey A. Barrett August 26, 2014 Abstract Hugh Everett III proposed his relative-state formulation of pure wave mechanics and probability problems by showing that, while counterintuitive, pure wave mechan- ics was nevertheless

  7. Mechanism design for fractional scheduling on unrelated George Christodoulou

    E-Print Network [OSTI]

    Koutsoupias, Elias

    Mechanism design for fractional scheduling on unrelated machines George Christodoulou Elias and randomized approximation algorithms. The mechanism design version of the scheduling problem was introduced by Nisan and Ronen [23]. In this paper1 , we consider the mechanism design version of the fractional

  8. Truthful and Near-Optimal Mechanism Design via Linear Programming

    E-Print Network [OSTI]

    Sandholm, Tuomas W.

    Truthful and Near-Optimal Mechanism Design via Linear Programming¬£ Ron Lavi√Ě ronlavi social-welfare maximization problem is NP-hard. 1 Introduction Mechanism design studies algorithmic. Mechanism design approaches this goal by specifying along with the algorithm a pricing scheme that can

  9. Mechanism Design for Fair Division: Allocating Divisible Items without Payments

    E-Print Network [OSTI]

    Cortes, Corinna

    A Mechanism Design for Fair Division: Allocating Divisible Items without Payments RICHARD COLE GOEL, Google Research, New York We revisit the classic problem of fair division from a mechanism design their valuations. For the very large class of homo- geneous valuations, we design a truthful mechanism

  10. Mechanism Design for Software Agents with Complete Information

    E-Print Network [OSTI]

    O'Connell, Tom

    Mechanism Design for Software Agents with Complete Information Thomas C. O'Connell a,,1 Richard EDepartment of Computer Science, University at Albany, SUNY, Albany, NY 12222 Abstract We investigate the mechanism design that arise in applying results from mechanism design to computational problems. In particular, our results

  11. Discrete mechanics, optimal control and formation flying spacecraft

    E-Print Network [OSTI]

    Patrick, George

    Discrete mechanics, optimal control and formation flying spacecraft Oliver Junge Center-Bl¨obaum partially supported by the CRC 376 Oliver Junge Discrete mechanics, optimal control and formation flying spacecraft p.1 #12;Outline mechanical optimal control problem direct discretization of the variational

  12. CLNS 96/1443 Peculiarities of Quantum Mechanics

    E-Print Network [OSTI]

    CLNS 96/1443 REVISED Peculiarities of Quantum Mechanics: Origins and Meaning 1 Yuri F. Orlov Floyd The most peculiar, specifically quantum, features of quantum mechanics --- quan≠ tum nonlocality mechanics 1 This paper, to be presented to the Nordic Symposium on Basic Problems in Quantum Physics, June

  13. Vibrational Mechanics: Nonlinear Dynamic Effects, General Ap-proach, Applications

    E-Print Network [OSTI]

    van der Heijden, Gert

    Review of: Vibrational Mechanics: Nonlinear Dynamic Effects, General Ap- proach, Applications Iliya a general mechanical approach (and philosophy) for the study of problems involving vibrations motion is considered. Equation (6) is the main equation of what the author calls vibrational mechanics

  14. Time is not the problem

    E-Print Network [OSTI]

    Olaf Dreyer

    2009-04-22

    Attempts to quantize general relativity encounter an odd problem. The Hamiltonian that normally generates time evolution vanishes in the case of general relativity as a result of diffeomorphism invariance. The theory seems to be saying that time does not exist. The most obvious feature of our world, namely that time seems to progress and that the world changes accordingly becomes a problem in this presumably fundamental theory. This is called the problem of time. In this essay we argue that this problem is the result of an unphysical idealization. We are caught in this "problem of time" trap because we took a wrong turn in the early days of relativity by permanently including a split of geometry and matter into our physical theories. We show that another possibility exists that circumvents the problem of time and also sheds new light on other problems like the cosmological constant problem and the horizon problem in early universe cosmology.

  15. The Primordial Lithium Problem

    E-Print Network [OSTI]

    Brian D. Fields

    2012-03-15

    Big-bang nucleosynthesis (BBN) theory, together with the precise WMAP cosmic baryon density, makes tight predictions for the abundances of the lightest elements. Deuterium and 4He measurements agree well with expectations, but 7Li observations lie a factor 3-4 below the BBN+WMAP prediction. This 4-5\\sigma\\ mismatch constitutes the cosmic "lithium problem," with disparate solutions possible. (1) Astrophysical systematics in the observations could exist but are increasingly constrained. (2) Nuclear physics experiments provide a wealth of well-measured cross-section data, but 7Be destruction could be enhanced by unknown or poorly-measured resonances, such as 7Be + 3He -> 10C^* -> p + 9B. (3) Physics beyond the Standard Model can alter the 7Li abundance, though D and 4He must remain unperturbed; we discuss such scenarios, highlighting decaying Supersymmetric particles and time-varying fundamental constants. Present and planned experiments could reveal which (if any) of these is the solution to the problem.

  16. Parallel problem generation for structured problems in mathematical programming†

    E-Print Network [OSTI]

    Qiang, Feng

    2015-11-26

    The aim of this research is to investigate parallel problem generation for structured optimization problems. The result of this research has produced a novel parallel model generator tool, namely the Parallel Structured ...

  17. Strange Bedfellows: Quantum Mechanics and Data Mining

    E-Print Network [OSTI]

    Marvin Weinstein

    2009-11-03

    Last year, in 2008, I gave a talk titled {\\it Quantum Calisthenics}. This year I am going to tell you about how the work I described then has spun off into a most unlikely direction. What I am going to talk about is how one maps the problem of finding clusters in a given data set into a problem in quantum mechanics. I will then use the tricks I described to let quantum evolution lets the clusters come together on their own.

  18. Physical Interpretations of Nilpotent Quantum Mechanics

    E-Print Network [OSTI]

    Peter Rowlands

    2010-04-09

    Nilpotent quantum mechanics provides a powerful method of making efficient calculations. More importantly, however, it provides insights into a number of fundamental physical problems through its use of a dual vector space and its explicit construction of vacuum. Physical interpretation of the nilpotent formalism is discussed with respect to boson and baryon structures, the mass-gap problem, zitterbewgung, Berry phase, renormalization, and related issues.

  19. 21PF overpack problems

    SciTech Connect (OSTI)

    Kovac, F.M.

    1995-12-31

    The 21PF overpack has had severe metal corrosion and stress corrosion cracking (SCC) for many years. The US Department of Transportation (DOT) and the US Nuclear Regulatory Commission (NRC) have disallowed the use of overpacks containing high chloride foam. Corrosion and SCC of 21PF overpacks have been documented and papers have been presented at conferences about these issues. Regulatory agencies have restricted 21PF overpack use and have requested data to determine if phenolic foam overpacks not meeting original design specifications will be authorized for continued use. This paper details some of the problems experienced by users and relates actions of the DOT and NRC concerning these packages. Industry is working to correct deficiencies, but if they are not successful, the entire uranium enrichment industry will be severely impacted.

  20. The Inhibiting Bisection Problem

    SciTech Connect (OSTI)

    Pinar, Ali; Fogel, Yonatan; Lesieutre, Bernard

    2006-12-18

    Given a graph where each vertex is assigned a generation orconsumption volume, we try to bisect the graph so that each part has asignificant generation/consumption mismatch, and the cutsize of thebisection is small. Our motivation comes from the vulnerability analysisof distribution systems such as the electric power system. We show thatthe constrained version of the problem, where we place either the cutsizeor the mismatch significance as a constraint and optimize the other, isNP-complete, and provide an integer programming formulation. We alsopropose an alternative relaxed formulation, which can trade-off betweenthe two objectives and show that the alternative formulation of theproblem can be solved in polynomial time by a maximum flow solver. Ourexperiments with benchmark electric power systems validate theeffectiveness of our methods.

  1. Modeling applied to problem solving

    E-Print Network [OSTI]

    Pawl, Andrew

    We describe a modeling approach to help students learn expert problem solving. Models are used to present and hierarchically organize the syllabus content and apply it to problem solving, but students do not develop and ...

  2. The optimization problem Genetic Algorithm

    E-Print Network [OSTI]

    Gimťnez, Domingo

    The optimization problem Genetic Algorithm Particle Swarm Optimization Experimental results for time-power optimization META, October 27-31, 2014 1 / 25 #12;The optimization problem Genetic Algorithm Particle Swarm Optimization Experimental results Conclusions Time and energy optimization Traditionally

  3. Using Differential Adhesion to Control Self-Assembly and Self-Repair of Collections of Modular Mobile Robots†

    E-Print Network [OSTI]

    Ottery, Peter

    This thesis presents a novel distributed control method which allows a collection of independently mobile robotic units, with two or three dimensional movement, to self-assemble into self-repairing hierarchical structures. ...

  4. Noether's first theorem in Hamiltonian mechanics

    E-Print Network [OSTI]

    G. Sardanashvily

    2015-10-13

    Non-autonomous non-relativistic mechanics is formulated as Lagrangian and Hamiltonian theory on fibre bundles over the time axis R. Hamiltonian mechanics herewith can be reformulated as particular Lagrangian theory on a momentum phase space. This facts enable one to apply Noether's first theorem both to Lagrangian and Hamiltonian mechanics. By virtue of Noether's first theorem, any symmetry defines a symmetry current which is an integral of motion in Lagrangian and Hamiltonian mechanics. The converse is not true in Lagrangian mechanics where integrals of motion need not come from symmetries. We show that, in Hamiltonian mechanics, any integral of motion is a symmetry current. In particular, an energy function relative to a reference frame is a symmetry current along a connection on a configuration bundle which is this reference frame. An example of the global Kepler problem is analyzed in detail.

  5. Computer Assisted Mechanics and Engineering Sciences Copyright 1999 by Polish Academy of Sciences

    E-Print Network [OSTI]

    Pownuk, Andrzej

    Computer Assisted Mechanics and Engineering Sciences Copyright © 1999 by Polish Academy of Sciences on the knowledge of Lipshitz constants [19]. In many mechanical and civil engineering optimization problems be applied to the following engineering problems: optimization of parameters of mechanical system [8]; shape

  6. Probabilistic Robotics The SLAM Problem

    E-Print Network [OSTI]

    Kosecka, Jana

    rule ∑ History of SLAM dates back to the mid-eighties (stone-age of mobile robotics) The SLAM Problem

  7. Subterranean barriers, methods, and apparatuses for forming, inspecting, selectively heating, and repairing same

    DOE Patents [OSTI]

    Nickelson, Reva A. (Shelley, ID); Sloan, Paul A. (Rigby, ID); Richardson, John G. (Idaho Falls, ID); Walsh, Stephanie (Idaho Falls, ID); Kostelnik, Kevin M. (Idaho, ID)

    2009-04-07

    A subterranean barrier and method for forming same are disclosed, the barrier including a plurality of casing strings wherein at least one casing string of the plurality of casing strings may be affixed to at least another adjacent casing string of the plurality of casing strings through at least one weld, at least one adhesive joint, or both. A method and system for nondestructively inspecting a subterranean barrier is disclosed. For instance, a radiographic signal may be emitted from within a casing string toward an adjacent casing string and the radiographic signal may be detected from within the adjacent casing string. A method of repairing a barrier including removing at least a portion of a casing string and welding a repair element within the casing string is disclosed. A method of selectively heating at least one casing string forming at least a portion of a subterranean barrier is disclosed.

  8. Weld Repair of a Stamped Pressure Vessel in a Radiologically Controlled Zone

    SciTech Connect (OSTI)

    Cannell, Gary L.; Huth, Ralph J.; Hallum, Randall T.

    2013-08-26

    In September 2012 an ASME B&PVC Section VIII stamped pressure vessel located at the DOE Hanford Site Effluent Treatment Facility (ETF) developed a through-wall leak. The vessel, a steam/brine heat exchanger, operated in a radiologically controlled zone (by the CH2MHill PRC or CHPRC), had been in service for approximately 17 years. The heat exchanger is part of a single train evaporator process and its failure caused the entire system to be shut down, significantly impacting facility operations. This paper describes the activities associated with failure characterization, technical decision making/planning for repair by welding, logistical challenges associated with performing work in a radiologically controlled zone, performing the repair, and administrative considerations related to ASME code requirements.

  9. Algorithms and Problem Solving Introduction

    E-Print Network [OSTI]

    Razak, Saquib

    Unit 16 1 Algorithms and Problem Solving ∑ Introduction ∑ What is an Algorithm? ∑ Algorithm Properties ∑ Example ∑ Exercises #12;Unit 16 2 What is an Algorithm? What is an Algorithm? ∑ An algorithm. ∑ The algorithm must be general, that is, it should solve the problem for all possible input sets to the problem

  10. On NP complete problems I

    E-Print Network [OSTI]

    Minoru Fujimoto; Kunihiko Uehara

    2008-09-05

    We study the quadratic residue problem known as an NP complete problem by way of the prime number and show that a nondeterministic polynomial process does not belong to the class P because of a random distribution of solutions for the quadratic residue problem.

  11. Chondrocyte outgrowth into a gelatin scaffold in a single impact load model of damage/repair - effect of BMP-2

    E-Print Network [OSTI]

    Henson, Frances M D; Vincent, Thea A

    2007-12-05

    damage repair response in mature equine articular cartilage explants following single impact load and subsequent culture [3]. This response is characterised Published: 5 December 2007 BMC Musculoskeletal Disorders 2007, 8:120 doi:10... ) degenerative joint disease, specifically osteoarthritis (OA) [2]. by the appearance of chondrocyte repair cells on damaged cartilage. This apparent mobilisation of chondrocytes has BMC Musculoskeletal Disorders 2007, 8:120 http://www.biomedcentral.com/1471...

  12. Precracked RC T-beams Repaired in Shear with Externally Bonded CFRP Sheets

    E-Print Network [OSTI]

    Dirar, Samir; Lees, Janet M.; Morley, Chris T.

    2012-03-01

    and repair of existing structures, advanced numerical analyses, glass fiber reinforced polymer pipelines and sustainable concrete. Chris Morley is a former Senior Lecturer in Concrete Structures at Cambridge University, UK. He has always been interested... , particularly in the case of bridges. Further factors that can have detrimental effects on capacity include corrosion of internal steel reinforcement, changes in use, poor initial design and more stringent assessment codes. One viable solution is to use fiber...

  13. Inhibition of Hsp27 Radiosensitizes Head-and-Neck Cancer by Modulating Deoxyribonucleic Acid Repair

    SciTech Connect (OSTI)

    Guttmann, David M.; Hart, Lori; Du, Kevin; Seletsky, Andrew; Koumenis, Constantinos

    2013-09-01

    Purpose: To present a novel method of tumor radiosensitization through Hsp27 knockdown using locked nucleic acid (LNA) and to investigate the role of Hsp27 in DNA double strand break (DSB) repair. Methods and Materials: Clonogenic survival assays, immunoblotting, the proximity ligation assay, and ?H2AX foci analysis were conducted in SQ20B and FaDu human head-and-neck cancer cell lines treated with Hsp27 LNA and Hsp27 short hairpin RNA (shRNA). Additionally, nude mice with FaDu flank tumors were treated with fractionated radiation therapy after pretreatment with Hsp27 LNA and monitored for tumor growth. Results: Hsp27 LNA and Hsp27 shRNA radiosensitized head-and-neck cancer cell lines in an Hsp27-dependent manner. Ataxia-Telangectasia Mutated-mediated DNA repair signaling was impaired in irradiated cells with Hsp27 knockdown. ATM kinase inhibition abrogated the radiosensitizing effect of Hsp27. Furthermore, Hsp27 LNA and shRNA both attenuated DNA repair kinetics after radiation, and Hsp27 was found to colocalize with ATM in both untreated and irradiated cells. Last, combined radiation and Hsp27 LNA treatment in tumor xenografts in nude mice suppressed tumor growth compared with either treatment alone. Conclusions: These results support a radiosensitizing property of Hsp27 LNA in vitro and in vivo, implicate Hsp27 in double strand break repair, and suggest that Hsp27 LNA might eventually serve as an effective clinical agent in the radiotherapy of head-and-neck cancer.

  14. Cell-autonomous progeroid changes in conditional mouse models for repair endonuclease XPG deficiency

    SciTech Connect (OSTI)

    Barnhoorn, Sander [Erasmus University Medical Center, Rotterdam (The Netherlands). Dept. of Genetics.; Uittenboogaard, Lieneke M. [Erasmus University Medical Center, Rotterdam (The Netherlands). Dept. of Genetics.; Jaarsma, Dick [Erasmus Univ. Medical Center, Rotterdam (The Netherlands). Dept. of Neuroscience.; Vermeij, Wilbert P. [Erasmus University Medical Center, Rotterdam (The Netherlands). Dept. of Genetics.; Tresini, Maria [Erasmus University Medical Center, Rotterdam (The Netherlands). Dept. of Genetics.; Weymaere, Michael [Erasmus University Medical Center, Rotterdam (The Netherlands). Dept. of Genetics.; Menoni, Hervť [Erasmus University Medical Center, Rotterdam (The Netherlands). Dept. of Genetics.; Brandt, Renata M. C. [Erasmus University Medical Center, Rotterdam (The Netherlands). Dept. of Genetics.; de Waard, Monique C. [VU Univ. Medical Center, Amsterdam (The Netherlands). Dept. of Intensive Care.; Botter, Sander M. [Uniklinik Balgrist, Zurich (Switzerland); Sarker, Altaf H. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Life Sciences Division.; Jaspers, Nicolaas G. J. [Erasmus University Medical Center, Rotterdam (The Netherlands). Dept. of Genetics; van der Horst, Gijsbertus T. J. [Erasmus University Medical Center, Rotterdam (The Netherlands). Dept. of Genetics.; Cooper, Priscilla K. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Life Sciences Division.; Hoeijmakers, Jan H. J. [Erasmus University Medical Center, Rotterdam (The Netherlands). Dept. of Genetics.; van der Pluijm, Ingrid [Erasmus University Medical Center, Rotterdam (The Netherlands). Dept. of Genetics and Dept. of Vascular Surgery.; Niedernhofer, Laura J. [The Scripps Research Institute, San Diego, CA (United States)

    2014-10-09

    As part of the Nucleotide Excision Repair (NER) process, the endonuclease XPG is involved in repair of helix-distorting DNA lesions, but the protein has also been implicated in several other DNA repair systems, complicating genotype-phenotype relationship in XPG patients. Defects in XPG can cause either the cancer-prone condition xeroderma pigmentosum (XP) alone, or XP combined with the severe neurodevelopmental disorder Cockayne Syndrome (CS), or the infantile lethal cerebro-oculo-facio-skeletal (COFS) syndrome, characterized by dramatic growth failure, progressive neurodevelopmental abnormalities and greatly reduced life expectancy. Here, we present a novel (conditional) Xpg-/- mouse model whichóin a C57BL6/FVB F1 hybrid genetic backgroundódisplays many progeroid features, including cessation of growth, loss of subcutaneous fat, kyphosis, osteoporosis, retinal photoreceptor loss, liver aging, extensive neurodegeneration, and a short lifespan of 4Ė5 months. We show that deletion of XPG specifically in the liver reproduces the progeroid features in the liver, yet abolishes the effect on growth or lifespan. In addition, specific XPG deletion in neurons and glia of the forebrain creates a progressive neurodegenerative phenotype that shows many characteristics of human XPG deficiency. Our findings therefore exclude that both the liver as well as the neurological phenotype are a secondary consequence of derailment in other cell types, organs or tissues (e.g. vascular abnormalities) and support a cell-autonomous origin caused by the DNA repair defect itself. In addition they allow the dissection of the complex aging process in tissue- and cell-type-specific components. Moreover, our data highlight the critical importance of genetic background in mouse aging studies, establish the Xpg-/- mouse as a valid model for the severe form of human XPG patients and segmental accelerated aging, and strengthen the link between DNA damage and aging.

  15. Lethal Hemorrhage Caused by Aortoesophageal Fistula Secondary to Stent-Graft Repair of the Thoracic Aorta

    SciTech Connect (OSTI)

    Sager, Hendrik B., E-mail: hendrik.sager@uk-sh.de [Universitaet zu Luebeck, Medizinische Klinik II (Germany); Wellhoener, Peter [Universitaet zu Luebeck, Medizinische Klinik I (Germany); Wermelt, Johanna A. [Klinikum Neustadt, Klinik fuer Innere Medizin (Germany); Schunkert, Heribert; Kurowski, Volkhard [Universitaet zu Luebeck, Medizinische Klinik II (Germany)

    2011-02-15

    Aortoesophageal fistula (AEF) is a rare but life-threatening complication after endovascular or surgical aortic repair. Here we report a patient with AEF secondary to aortic stent-placement 2 years earlier who presented with hematemesis and died from hemorrhagic shock. By means of this case and the literature, we highlight potential bleeding sources in such a scenario because this is of crucial importance for the management strategy.

  16. Cell-autonomous progeroid changes in conditional mouse models for repair endonuclease XPG deficiency

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Barnhoorn, Sander; Uittenboogaard, Lieneke M.; Jaarsma, Dick; Vermeij, Wilbert P.; Tresini, Maria; Weymaere, Michael; Menoni, Hervť; Brandt, Renata M. C.; de Waard, Monique C.; Botter, Sander M.; et al

    2014-10-09

    As part of the Nucleotide Excision Repair (NER) process, the endonuclease XPG is involved in repair of helix-distorting DNA lesions, but the protein has also been implicated in several other DNA repair systems, complicating genotype-phenotype relationship in XPG patients. Defects in XPG can cause either the cancer-prone condition xeroderma pigmentosum (XP) alone, or XP combined with the severe neurodevelopmental disorder Cockayne Syndrome (CS), or the infantile lethal cerebro-oculo-facio-skeletal (COFS) syndrome, characterized by dramatic growth failure, progressive neurodevelopmental abnormalities and greatly reduced life expectancy. Here, we present a novel (conditional) Xpg-/- mouse model whichóin a C57BL6/FVB F1 hybrid genetic backgroundódisplays manymore†Ľprogeroid features, including cessation of growth, loss of subcutaneous fat, kyphosis, osteoporosis, retinal photoreceptor loss, liver aging, extensive neurodegeneration, and a short lifespan of 4Ė5 months. We show that deletion of XPG specifically in the liver reproduces the progeroid features in the liver, yet abolishes the effect on growth or lifespan. In addition, specific XPG deletion in neurons and glia of the forebrain creates a progressive neurodegenerative phenotype that shows many characteristics of human XPG deficiency. Our findings therefore exclude that both the liver as well as the neurological phenotype are a secondary consequence of derailment in other cell types, organs or tissues (e.g. vascular abnormalities) and support a cell-autonomous origin caused by the DNA repair defect itself. In addition they allow the dissection of the complex aging process in tissue- and cell-type-specific components. Moreover, our data highlight the critical importance of genetic background in mouse aging studies, establish the Xpg-/- mouse as a valid model for the severe form of human XPG patients and segmental accelerated aging, and strengthen the link between DNA damage and aging.ę†less

  17. Quality Improvement Guidelines for Imaging Detection and Treatment of Endoleaks following Endovascular Aneurysm Repair (EVAR)

    SciTech Connect (OSTI)

    Rand, T.; Uberoi, R.; Cil, B.; Munneke, G.; Tsetis, D.

    2013-02-15

    Major concerns after aortic aneurysm repair are caused by the presence of endoleaks, which are defined as persistent perigraft flow within the aortic aneurysm sac. Diagnosis of endoleaks can be performed with various imaging modalities, and indications for treatment are based on further subclassifications. Early detection and correct classification of endoleaks are crucial for planning patient management. The vast majority of endoleaks can be treated successfully by interventional means. Guidelines for Imaging Detection and Treatment of endoleaks are described in this article.

  18. Mechanical & Biomedical Engineering

    E-Print Network [OSTI]

    Barrash, Warren

    Mechanical & Biomedical Engineering Department BACHELOR OF SCIENCE IN MECHANICAL ENGINEERING COURSE 105 Mechanical Engineering Graphics 3 CHEM 111L College Chemistry Lab (DLN) 1 ENGL 102 English PHYS 211 Mechanics, Waves & Heat (DLN) 4 UF 100 Intellectual Foundations 3 PHYS 211L Mechanics, Waves

  19. Mechanical Engineering & Thermal Group

    E-Print Network [OSTI]

    Mojzsis, Stephen J.

    LASP's mechanical analysts also lead mechanical verification testing including: random vibration, forceMechanical Engineering & Thermal Group The Mechanical Engineering (ME) & Thermal Group at LASP has, and ground- based mechanical systems. Instrument Design Building on decades of design experience that has

  20. A deficiency in chromatin repair, genetic instability, and predisposition to cancer

    SciTech Connect (OSTI)

    Sanford, K.K.; Parshad, R.; Gantt, R.R.; Tarone, R.E. (National Cancer Institute, Bethesda, MD (USA))

    1989-01-01

    This review traces steps leading to malignant neoplastic transformation of rodent and human cells in culture and in vivo. Emphasis is placed on an abnormal response characterized by persistent chromatid damage following irradiation of cells in culture with X-rays or fluorescent light during G2 phase of the cell cycle. Evidence is presented that deficient or unbalanced DNA repair during G2 accounts for the abnormal response. This G2 repair deficiency can be inherited or acquired by normal tissue cells during the process of or following attainment of infinite lifespan. It appears as an early, possibly initiating step in neoplastic transformation. It characterizes all human tumor cells examined irrespective of histopathology or tissue of origin. It has a genetic basis. In an animal model, the BALB/c mouse, this phenotype is associated with genes on chromosomes 1 and 4. It characterizes skin fibroblasts and blood lymphocytes from individuals with genetic or familial conditions predisposing to cancer and can be used to identify clinically normal family members carrying a gene(s) for any one of the three cancer-prone genetic disorders studied to date. Furthermore, it can provide the basis of a test for carriers of genes predisposing to a high risk of cancer. We conclude that the G2 repair deficiency, whether inherited or acquired, is a prerequisite for cancer development and that it accounts for the genetic instability of the cancer cell. 167 refs.

  1. ASTRID sodium cooled fast reactor: Program for improving in service inspection and repair

    SciTech Connect (OSTI)

    Jadot, F.; De Dinechin, G.; Augem, J. M.; Sibilo, J.

    2011-07-01

    In the frame of the CEA, EDF, AREVA coordinated research program for the development of Generation IV sodium-cooled fast reactors (SFR), the ASTRID project was launched in 2010. For the future prototype, the improvement of in-service inspection and repair (ISI and R) capabilities was identified as a major issue. Following the pluri-annual SFR research program, the ISI and R main R and D axes remain: i) improvement of the primary system conceptual design, ii) development of measurement and inspection techniques (continuous monitoring instrumentation and periodic inspection tools), iii) accessibility and associated robotics, and iv) development and validation of repair processes. Associated ISI and R needs are being defined through an iterative method between designers and instrumentation specialists: adaptation of the Design to ISI and R requirements, fission chamber development, validation of the ultrasonic and chemical transducers, of ultrasonic non destructive simulation, of acoustic surveillance, of laser repair intervention processes, of connected robotic equipment. Moreover, CEA, as leader of the ASTRID Project, is willing to find new contributors, partners or suppliers, in order to get innovative, diversified, exhaustive and efficient solutions. (authors)

  2. Romanovski polynomials in selected physics problems

    E-Print Network [OSTI]

    A. P. Raposo; H. J. Weber; D. Alvarez-Castillo; M. Kirchbach

    2007-06-26

    We briefly review the five possible real polynomial solutions of hypergeometric differential equations. Three of them are the well known classical orthogonal polynomials, but the other two are different with respect to their orthogonality properties. We then focus on the family of polynomials which exhibits a finite orthogonality. This family, to be referred to as the Romanovski polynomials, is required in exact solutions of several physics problems ranging from quantum mechanics and quark physics to random matrix theory. It appears timely to draw attention to it by the present study. Our survey also includes several new observations on the orthogonality properties of the Romanovski polynomials and new developments from their Rodrigues formula.

  3. An inverse problem for Schwinger pair production

    E-Print Network [OSTI]

    Hebenstreit, Florian

    2015-01-01

    The production of electron-positron pairs in time-dependent electric fields (Schwinger mechanism) depends non-linearly on the applied field profile. Accordingly, the resulting momentum spectrum is extremely sensitive to small variations of the field parameters. Owing to this non-linear dependence it is so far unpredictable how to choose a field configuration such that a predetermined momentum distribution is generated. We show that quantum kinetic theory along with optimal control theory can be used to approximately solve this inverse problem for Schwinger pair production. We exemplify this by studying the superposition of a small number of harmonic components resulting in predetermined signatures in the asymptotic momentum spectrum. In the long run, our results could facilitate the observation of this yet unobserved pair production mechanism in quantum electrodynamics by providing suggestions for tailored field configurations.

  4. PROBLEM 1: TIME DEPENDENT CONSOLIDATION OF FINE POWDERS Karen Bliss1

    E-Print Network [OSTI]

    , plasticity theory, and soil mechanics. Advances in computer technology continually warrant a closer look. There is a parallel consolidation problem in soil mechanics that occurs in water saturated clays and a model is used 1950's. Jenike's original work in this field was built on foundations of continuum mechanics

  5. Mechanical, Industrial & Manufacturing

    E-Print Network [OSTI]

    Balasubramanian, Ravi

    Mechanical, Industrial & Manufacturing Engineering (MIME) COLLEGE OF ENGINEERING FY2013 Oregon graduate degrees (MS, MEng, PhD) in mechanical engineering, industrial engineering, and materials science. We offer bachelor's degrees in mechanical, industrial, manufacturing, and energy systems engineering

  6. Mechanical & Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical & Aerospace Engineering Despite an enormous range of applications and centuries. Nicholas Ouellette is an Associate Professor in the Department of Mechanical Engineering & Materials Structures in Turbulent Flow Nicholas Ouellette Department of Mechanical Engineering & Material Sciences Yale

  7. Mechanical Systems Signal Processing

    E-Print Network [OSTI]

    Verleysen, Michel

    Mechanical Systems and Signal Processing Mechanical Systems and Signal Processing 22 (2008) 155 Department of Mechanical Engineering, University of Sheffield, Mappin Street S1 3JD Sheffield, UK Received 27

  8. Mechanical & Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical & Aerospace Engineering This presentation presents the stability analysis of time- delay of the Department of Mechanical and Industrial Engineering, Southern Illinois University Edwardsville, where he has Gu Dept. of Mechanical & Industrial Engineering Southern Illinois University, Edwardsville March 27

  9. Mechanical & Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical & Aerospace Engineering With the increases in computational power and numerical methods a series of research challenges. These challenges involve many branches of mechanical engineering: mechanics, dynamics, tribology, statistical modeling, experimentation, and numerical methods. During

  10. Mechanical & Industrial Engineering

    E-Print Network [OSTI]

    Mountziaris, T. J.

    Mechanical & Industrial Engineering 1 Welcome MIE Industrial Advisory Board October 15, 2010 #12;Mechanical & Industrial Engineering 2 MIE Dorothy Adams Undergraduate/Graduate Secretary David Schmidt Associate Professor & Graduate Program Director #12;Mechanical & Industrial Engineering 3 MIE James Rinderle

  11. Mechanical & Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical & Aerospace Engineering Today's design environments take advantage of powerful professor of Mechanical Engineering at Carnegie Mellon University. He is the founder of Visual Design award and American Society of Mechanical Engineers Design Automation Society Young Investigator Award

  12. Department of Mechanical & Aerospace

    E-Print Network [OSTI]

    Zhigilei, Leonid V.

    in mechanics, electrical theory, kinematics, thermodynamics, fluid mechanics, heat transfer and materials dynamics, fluid dynamics, propulsion and structures. While each program features a solid technicalDeveloping Leaders of Innovation Department of Mechanical & Aerospace Engineering #12;Emphasizing

  13. New Solutions of Half-Space Contact Problems Using Potential Theory, Surface Elasticity and Strain Gradient Elasticity†

    E-Print Network [OSTI]

    Zhou, Songsheng

    2012-02-14

    - the adhesive contact mechanics, surface elasticity and strain gradient elasticity - are employed to study the mechanical behaviors of a semi-infinite solid induced by the boundary forces. A unified treatment of axisymmetric adhesive contact problems...

  14. Journal of the Mechanics and Physics of Solids 56 (2008) 16731692 Thermoelastic contact mechanics for a flat punch sliding over a

    E-Print Network [OSTI]

    Paulino, Glaucio H.

    2008-01-01

    Choia,√, Glaucio H. Paulinob a School of Mechanical and Automotive Engineering, Kookmin UniversityJournal of the Mechanics and Physics of Solids 56 (2008) 1673≠1692 Thermoelastic contact mechanics July 2007; accepted 18 July 2007 Abstract The problem of thermoelastic contact mechanics

  15. Mechanical & Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical & Aerospace Engineering The gap between `advanced' prosthetic technology was educated in Mechanical and Biomedical Engineering at the University of Illinois and Northwestern University

  16. Mechanical Performance Extreme Conditions

    E-Print Network [OSTI]

    Mechanical Performance ≠ Extreme Conditions METALS This project provides property data, metrology information using the image correlation technique. With this instrument, high strain rate mechanical testing

  17. Mechanical & Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical & Aerospace Engineering In the pursuit of developing manned, reusable hypersonic will experience thermal and mechanical loads. The research presented will discuss advancements in structural

  18. Statistical Mechanics of Black Holes

    E-Print Network [OSTI]

    B. Harms; Y. Leblanc

    1992-05-11

    We analyze the statistical mechanics of a gas of neutral and charged black holes. The microcanonical ensemble is the only possible approach to this system, and the equilibrium configuration is the one for which most of the energy is carried by a single black hole. Schwarzschild black holes are found to obey the statistical bootstrap condition. In all cases, the microcanonical temperature is identical to the Hawking temperature of the most massive black hole in the gas. U(1) charges in general break the bootstrap property. The problems of black hole decay and of quantum coherence are also addressed.

  19. UNIVERSITY OF MICHIGAN DEPARTMENT OF MECHANICAL ENGINEERING

    E-Print Network [OSTI]

    Papalambros, Panos

    UNIVERSITY OF MICHIGAN DEPARTMENT OF MECHANICAL ENGINEERING ANN ARBOR, MI 48109 TECHNICAL REPORT UM-MEAM-96-18 DECOMPOSITION ANALYSIS OF AN AUTOMOTIVE POWERTRAIN DESIGN PROBLEM: MODEL DEVELOPMENT Division, Dearborn, Michigan , USA **Automotive Research Center, The University of Michigan, Ann Arbor

  20. Hamilton-Jacobi Fractional Sequential Mechanics

    E-Print Network [OSTI]

    Eqab M. Rabei; Bashar S. Ababneh

    2007-04-04

    As a continuation of Rabei et al. work [11], the Hamilton- Jacobi partial differential equation is generalized to be applicable for systems containing fractional derivatives. The Hamilton- Jacobi function in configuration space is obtained in a similar manner to the usual mechanics. Two problems are considered to demonstrate the application of the formalism. The result found to be in exact agreement with Agrawal's formalism.

  1. Associate Professor of Mechanics, Lehigh University,

    E-Print Network [OSTI]

    of Dissimilar Materials With Cracks This paper considers the problem of bending of a plate composed of two N. S. F. Fellow. Department of Mechanics. Lehigh University. Bethlehem, Pa. The Bending of Plates equations occurring in the extension and bending of cracked plates composed of dissimilar materials. A n u m

  2. The Fluid Mechanics of Carbon Dioxide Sequestration

    E-Print Network [OSTI]

    Huppert, Herbert

    with a potentially disastrous global problem owing to the current emission of 32 gigatonnes of carbon dioxide (CO2The Fluid Mechanics of Carbon Dioxide Sequestration Herbert E. Huppert1-3 and Jerome A. Neufeld4 1 FurtherANNUAL REVIEWS #12;1. INTRODUCTION Undeniably, the average global carbon dioxide (CO2) content

  3. ACOUSTICAL IMAGING AND MECHANICAL PROPERTIES OF SOFT ROCK AND MARINE SEDIMENTS

    SciTech Connect (OSTI)

    Thurman E. Scott, Jr., Ph.D.; Musharraf Zaman, Ph.D.; Younane Abousleiman, Ph.D.

    2001-04-01

    The oil and gas industry has encountered significant problems in the production of oil and gas from weak rocks (such as chalks and limestones) and from unconsolidated sand formations. Problems include subsidence, compaction, sand production, and catastrophic shallow water sand flows during deep water drilling. Together these cost the petroleum industry hundreds of millions of dollars annually. The goals of this first quarterly report is to document the progress on the project to provide data on the acoustic imaging and mechanical properties of soft rock and marine sediments. The project is intended to determine the geophysical (acoustic velocities) rock properties of weak, poorly cemented rocks and unconsolidated sands. In some cases these weak formations can create problems for reservoir engineers. For example, it cost Phillips Petroleum 1 billion dollars to repair of offshore production facilities damaged during the unexpected subsidence and compaction of the Ekofisk Field in the North Sea (Sulak 1991). Another example is the problem of shallow water flows (SWF) occurring in sands just below the seafloor encountered during deep water drilling operations. In these cases the unconsolidated sands uncontrollably flow up around the annulus of the borehole resulting in loss of the drill casing. The $150 million dollar loss of the Ursa development project in the U.S. Gulf Coast resulted from an uncontrolled SWF (Furlow 1998a,b; 1999a,b). The first three tasks outlined in the work plan are: (1) obtain rock samples, (2) construct new acoustic platens, (3) calibrate and test the equipment. These have been completed as scheduled. Rock Mechanics Institute researchers at the University of Oklahoma have obtained eight different types of samples for the experimental program. These include: (a) Danian Chalk, (b) Cordoba Cream Limestone, (c) Indiana Limestone, (d) Ekofisk Chalk, (e) Oil Creek Sandstone, (f) unconsolidated Oil Creek sand, and (g) unconsolidated Brazos river sand. These weak rocks and sands are intended to represent analogs to the formations that present oil and gas engineers with problems during oil and gas production and drilling operations. A series of new axial acoustic sensors have been constructed (and tested) to allow measurement of compressional and shear wave velocities during high pressure triaxial tests on these weak rock and sand samples. In addition, equipment to be utilized over the next 18 months of the project have tested and calibrated. These include the load frames, triaxial pressure cells, pressure sensors, load cells, extensometers, and oscilloscopes have been calibrated and tested. The multichannel acoustic emission and acoustic pulse transmission systems have also been tested. Graduate research assistant, research faculty, and the laboratory technician have begun Tasks 4 and 5 which involve preparing the sand samples and rock samples for testing. The construction of the lateral acoustic sensors has also been started during this quarter as outlined in the project timeline. With the equipment having been tested and calibrated, and the samples now being prepared, the experiments are on schedule to be started in April, 2001.

  4. The mechanical behavior of heavily overconsolidated resedimented Boston Blue Clay

    E-Print Network [OSTI]

    Vargas Bustamante, Albalyra Geraldine

    2013-01-01

    Geotechnical engineers encounter some of the most challenging problems in heavily overconsolidated soils. Clays under this condition originated in nature or man-made construction. This thesis investigates the mechanical ...

  5. Mechanical Engineering Graduate Student

    E-Print Network [OSTI]

    Wisconsin at Madison, University of

    Mechanical Engineering Graduate Student Handbook January 2015 Department of Mechanical Engineering University of Wisconsin-Madison #12;1 Mechanical Engineering Web Page: http://www.engr.wisc.edu/me Graduate & Terrace Chairs) and Samantha Stepp (ME Building) #12;2 Department of Mechanical Engineering AGUIDE

  6. Mechanical & Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical & Aerospace Engineering Bone is a biological material with excellent material properties the properties at lower level serve as inputs for modeling at the next structural level. Mechanical properties and applied mechanics at Northwestern University. Prior to joining the faculty of mechanical engineering

  7. Mechanical & Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical & Aerospace Engineering Strategic Plan 2014-2018 College of Engineering, Architecture & Technology #12;Mechanical and Aerospace Engineering at Oklahoma State University was organized as Mechanical the strongest in the nation. MAE is proud to continue in this fine tradition, forging high quality mechanical

  8. Mechanical Engineering David Sumner

    E-Print Network [OSTI]

    Saskatchewan, University of

    Mechanical Engineering David Sumner david.sumner@usask.ca #12;Mechanical Engineering? ∑ Design, production and use of mechanical systems that control and transform energy ∑ Focused on engineering systems that involve heat, energy and motion ∑ The broadest engineering discipline #12;Subject Areas ∑ Fluid mechanics

  9. Mechanical & Industrial Engineering

    E-Print Network [OSTI]

    Mountziaris, T. J.

    Mechanical & Industrial Engineering 1 Welcome MIE Industrial Advisory Board May 5th, 2011 #12;Mechanical & Industrial Engineering 2 IAB 2010-2011 ∑ David K. Anderson ≠ Alden Research Laboratory, Inc went on for three weeks Mechanical & Industrial Engineering 6 #12;Reza Shahbazian Yassar Mechanical

  10. Mechanical & Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical & Aerospace Engineering The science of robotics is a unique combination of mechanical in Dayton, OH. Dr. Sodemann received a PhD in Mechanical Engineering from the Georgia Institute to recent advances in the science of robotics, and thus the machines perform primarily as mechanical devices

  11. Mechanical & Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical & Aerospace Engineering Nanocrystal superlattices are materials formed by assembly Professor in the Department of Mechanical Engineering and Applied Mechanics at the University her B.S. in Mechanical Engineering magna cum laude from Rice University in 1994 and was elected to Phi

  12. Mechanical & Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical & Aerospace Engineering This talk concerns the effective behavior of heterogeneous media Science as well as the Executive Officer for Mechanical and Civil Engineering at the California Institute in Applied Mechanics from the American Society of Mechanical Engineers in 2004. He is currently an Editor

  13. INTRODUCTION TO THE MECHANICS

    E-Print Network [OSTI]

    Kaminski, Edouard

    INTRODUCTION TO THE MECHANICS OF A CONTINUOUS MEDIUM Lawrence E. Malvern Professor of Mechanics princi- ples common to all branches of solid and fluid mechanics, designed to appeal to the intuition science. The book arose from the need to provide a general preparation in contin- uum mechanics

  14. Unstable quasiperiodic solutions for the 2D Poiseuille problem

    E-Print Network [OSTI]

    Barcelona, Universitat de

    problem in fluid mechanics is the transition from laminar to turbulent flow. In this work we analyze of the flow of a viscous incompressible fluid, in a channel between two parallel walls at y = \\Sigmah. We solution for (1)--(2) known as the basic or laminar flow that has a parabolic profile, namely u b (y) = 1

  15. N-Body Problem Encyclopedia of Nonlinear Science

    E-Print Network [OSTI]

    Diacu, Florin

    The Newtonian N-body problem of celestial mechanics is a mathemati- cal generalization of the solar system of the distance. The equations of motion are given by the 6N-dimensional system of di#11;erential equations ( _ q is the potential function, U(q) representing the potential energy. Standard results of the theory of di#11;erential

  16. Multivariate Multi-Model Approach for Globally Multimodal Problems

    E-Print Network [OSTI]

    Chu, Hao-hua

    Multivariate Multi-Model Approach for Globally Multimodal Problems Chung-Yao Chuang Institute this source of difficulty, we designed an EDA that builds and samples multiple probabilistic models at each adopt multivariate probabilis- tic models. Furthermore, we have also devised a mechanism

  17. Repair of DNA double strand breaks and radiosensitivity: modulation of DNA repair and radiosensitivity by microRNA-335 and mtPAP

    E-Print Network [OSTI]

    Martin, Nathan

    2014-01-01

    DDR by at least three mechanisms: 1) maintaining ROS homeostasis, 2) mediating apoptotic signals, and 3) producing energy

  18. Proposal to negotiate the renewal of an existing blanket purchase contract for the repair, reconditioning or replacement of klystrons for CTF3 and associated accessories

    E-Print Network [OSTI]

    2012-01-01

    Proposal to negotiate the renewal of an existing blanket purchase contract for the repair, reconditioning or replacement of klystrons for CTF3 and associated accessories

  19. test problem for packing_sumit

    E-Print Network [OSTI]

    chenwang

    2006-07-21

    Test problems of circles in circle packing with constraints and known ... test problems for circles packing problem with the optimal solutions known. That is†...

  20. MechanicalEngineering The Department of Mechanical

    E-Print Network [OSTI]

    for the informed development and optimization of materials. This talk will present our recent work on exploring, Ph.D. Associate Professor Department of Mechanical Engineering Department of Materials Science to thermo-mechanical loads is a fundamental requirement in the characterization of materials and structures

  1. Development and validation of nondestructive inspection techniques for composite doubler repairs on commercial aircraft

    SciTech Connect (OSTI)

    Roach, D.; Walkington, P.

    1998-05-01

    Composite doublers, or repair patches, provide an innovative repair technique which can enhance the way aircraft are maintained. Instead of riveting multiple steel or aluminum plates to facilitate an aircraft repair, it is possible to bond a single boron-epoxy composite doubler to the damaged structure. In order for the use of composite doublers to achieve widespread use in the civil aviation industry, it is imperative that methods be developed which can quickly and reliably assess the integrity of the doubler. In this study, a specific composite application was chosen on an L-1011 aircraft in order to focus the tasks on application and operation issues. Primary among inspection requirements for these doublers is the identification of disbonds, between the composite laminate and aluminum parent material, and delaminations in the composite laminate. Surveillance of cracks or corrosion in the parent aluminum material beneath the doubler is also a concern. No single nondestructive inspection (NDI) method can inspect for every flaw type, therefore it is important to be aware of available NDI techniques and to properly address their capabilities and limitations. A series of NDI tests were conducted on laboratory test structures and on full-scale aircraft fuselage sections. Specific challenges, unique to bonded composite doubler applications, were highlighted. An array of conventional and advanced NDI techniques were evaluated. Flaw detection sensitivity studies were conducted on applicable eddy current, ultrasonic, X-ray and thermography based devices. The application of these NDI techniques to composite doublers and the results from test specimens, which were loaded to provide a changing flaw profile, are presented in this report. It was found that a team of these techniques can identify flaws in composite doubler installations well before they reach critical size.

  2. Suberoylanilide Hydroxyamic Acid Modification of Chromatin Architecture Affects DNA Break Formation and Repair

    SciTech Connect (OSTI)

    Singh, Sheetal; Le Hongan; Shih, S.-J.; Ho, Bay [Department of Radiation Oncology, University of California at Davis, 4501 X St., Sacramento, California 95817 (United States); Vaughan, Andrew T., E-mail: andrew.vaughan@ucdmc.ucdavis.ed [Department of Radiation Oncology, University of California at Davis, 4501 X St., Sacramento, California 95817 (United States); Department of Veterans Affairs, Mather, California 95655 (United States)

    2010-02-01

    Purpose: Chromatin-modifying compounds that inhibit the activity of histone deacetylases have shown potency as radiosensitizers, but the action of these drugs at a molecular level is not clear. Here we investigated the effect of suberoylanilide hydroxyamic acid (SAHA) on DNA breaks and their repair and induction of rearrangements. Methods and Materials: The effect of SAHA on both clonogenic survival and repair was assessed using cell lines SCC-25, MCF7, and TK6. In order to study unique DNA double-strand breaks, anti-CD95 antibody was employed to introduce a DNA double-strand break at a known location within the 11q23 region. The effects of SAHA on DNA cleavage and rearrangements were analyzed by ligation-mediated PCR and inverse PCR, respectively. Results: SAHA acts as radiosensitizer at 1 {mu}M, with dose enhancement factors (DEFs) at 10% survival of: SCC-25 - 1.24 +- 0.05; MCF7 - 1.16 +- 0.09 and TK6 - 1.17 +- 0.05, and it reduced the capacity of SCC-25 cells to repair radiation induced lesions. Additionally, SAHA treatment diffused site-specific fragmentation over at least 1 kbp in TK6 cells. Chromosomal rearrangements produced in TK6 cells exposed to SAHA showed a reduction in microhomology at the breakpoint between 11q23 and partner chromosomes. Conclusions: SAHA shows efficacy as a radiosensitizer at clinically obtainable levels. In its presence, targeted DNA strand breaks occur over an expanded region, indicating increased chromatin access. The rejoining of such breaks is degraded by SAHA when measured as rearrangements at the molecular level and rejoining that contributes to cell survival.

  3. MATRIXDEPENDENT MULTIGRIDHOMOGENIZATION FOR DIFFUSION PROBLEMS

    E-Print Network [OSTI]

    Bebendorf, Mario

    , such as matrix≠ dependent prolongations and the construction of coarse≠grid operators by means of the Galerkin. Introduction. Solutions for problems which model locally strong varying phe≠ nomena on a micro≠scale level require that all length scales present in the problem are completely resolved. However, due to storage

  4. TECHNOLOGY TRANSFER: PROBLEMS AND PROSPECTS

    E-Print Network [OSTI]

    TECHNOLOGY TRANSFER: PROBLEMS AND PROSPECTS Jesse w. Fussell Department of Defense 9800 Savage Road of technology transfer in this technical area in the past, to forecast prospects for technology transfer in the future, and to suggest some ideas for stimulating the process. 2. TECHNOLOGY TRANSFER PROBLEMS Many

  5. Motion Planning for Dynamic Variable Inertia Mechanical Systems with Non-holonomic

    E-Print Network [OSTI]

    Choset, Howie

    generation problem for other simpler types of mechanical systems. Finally, we apply our analysis to a novel analysis toward underactuated mechanical systems, that is, systems that do not have as many actuators seem- ingly different families of mechanical systems, principally kinematic and purely mechanical

  6. TENTH WORLD CONGRESS ON THE THEORY OF MACHINE AND MECHANISMS

    E-Print Network [OSTI]

    Mavroidis, Constantinos

    BODY DISPLACEMENT ANALYSIS USING THE METHOD OF LOCI AND ITS APPLICATION IN THE DIRECT KINEMATICS kinematics problem of special hybrid serial and parallel mechanisms, which can be used in assembly tasks. The solutions to these problems are directly related to the forward kinematics analysis of special types

  7. JAG Tearing Technique with Radiofrequency Guide Wire for Aortic Fenestration in Thoracic Endovascular Aneurysm Repair

    SciTech Connect (OSTI)

    Ricci, Carmelo [Azienda Ospedaliera Universitaria Senese, Policlinico Santa Maria alle Scotte, Radiologia Interventistica (Italy); Ceccherini, Claudio, E-mail: claudiocec@hotmail.it; Leonini, Sara [Radiologia Universitaria, Azienda Ospedaliera Universitaria Senese, Policlinico Santa Maria alle Scotte (Italy); Cini, Marco; Vigni, Francesco [Azienda Ospedaliera Universitaria Senese, Policlinico Santa Maria alle Scotte, Radiologia Interventistica (Italy); Neri, Eugenio; Tucci, Enrico; Benvenuti, Antonio; Tommasino, Giulio; Sassi, Carlo [Azienda Ospedaliera Universitaria Senese, Policlinico Santa Maria alle Scotte, Chirurgia dell'Aorta Toracica (Italy)

    2012-02-15

    An innovative approach, the JAG tearing technique, was performed during thoracic endovascular aneurysm repair in a patient with previous surgical replacement of the ascending aorta with a residual uncomplicated type B aortic dissection who developed an aneurysm of the descending thoracic aorta with its lumen divided in two parts by an intimal flap. The proximal landing zone was suitable to place a thoracic stent graft. The distal landing zone was created by cutting the intimal flap in the distal third of the descending thoracic aorta with a radiofrequency guide wire and intravascular ultrasound catheter.

  8. MechanicalEngineering Colloquium The Department of Mechanical

    E-Print Network [OSTI]

    MechanicalEngineering Colloquium The Department of Mechanical Engineering PRESENTS John C. Bischof Distinguished Professor Mechanical and Biomedical Engineering Chair, Mechanical Engineering University in the Departments of Mechanical and Biomedical Engineering and the inaugural Carl and Janet Kuhrmeyer Chair

  9. SEACAS Theory Manuals: Part 1. Problem Formulation in Nonlinear Solid Mechancis

    SciTech Connect (OSTI)

    Attaway, S.W.; Laursen, T.A.; Zadoks, R.I.

    1998-08-01

    This report gives an introduction to the basic concepts and principles involved in the formulation of nonlinear problems in solid mechanics. By way of motivation, the discussion begins with a survey of some of the important sources of nonlinearity in solid mechanics applications, using wherever possible simple one dimensional idealizations to demonstrate the physical concepts. This discussion is then generalized by presenting generic statements of initial/boundary value problems in solid mechanics, using linear elasticity as a template and encompassing such ideas as strong and weak forms of boundary value problems, boundary and initial conditions, and dynamic and quasistatic idealizations. The notational framework used for the linearized problem is then extended to account for finite deformation of possibly inelastic solids, providing the context for the descriptions of nonlinear continuum mechanics, constitutive modeling, and finite element technology given in three companion reports.

  10. Operational results of shaft repair by installing stave type cooler at Kimitsu Nos. 3 and 4 blast furnaces

    SciTech Connect (OSTI)

    Oda, Hiroshi; Amano, Shigeru; Sakamoto, Aiichiro; Anzai, Osamu [Nippon Steel Corp., Kimitsu, Chiba (Japan). Kimitsu Works; Nakagome, Michiru; Kuze, Toshisuke [Nippon Steel Corp., Futtsu, Chiba (Japan); Imuta, Akira [Nippon Steel Corp., Tokyo (Japan). Plant and Machinery Div.

    1997-12-31

    Nos. 3 and 4 blast furnaces in Nippon Steel Corporation Kimitsu Works were both initially fitted with cooling plate systems. With the aging of each furnace, the damage to their respective inner-shaft profiles had become serious. Thus, in order to prevent operational change and prolong the furnace life, the inner-shaft profile of each furnace was repaired by replacing the former cooling plate system with the stave type cooler during the two-week-shutdowns. With this repair, stability of burden descent and gas flow near the wall part of the furnace have been achieved. Thus the prolongation of the furnace life is naturally expected.

  11. Mechanical & Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical & Aerospace Engineering We introduce phonon recycling (local reabsorption of emitted) is Professor in Department of Mechanical Engineering and in Applied Physics Program, University of Michigan of Mechanical Engineering University of Michigan November 1, 2013 at 1:30pm in SCOB 228 School for Engineering

  12. Mechanical and Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical and Aerospace Engineering seminar Manipulation of Energy and Mass Transport at Micro as an assistant professor in the Department of Mechanical Engineering and was promoted to an associate professor award in 2007. Dr. Deyu Li Department of Mechanical Engineering Vanderbilt University January 20, 2012

  13. Mechanical & Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical & Aerospace Engineering Thermal transport plays an important role in energy conversion conductivity and phonon transport mechanisms over the past 2 decades, owing much to the challenging needs Faculty Fellow in Engineering and an Associate Professor of Mechanical Engineering directing the Nano

  14. Mechanical & Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical & Aerospace Engineering Interfacial flows are multi-material flows comprised of two and Solid Mechanics group in the Theoretical Division. Her research focuses on the development of numerical, and nuclear energy. She is a member of the American Society of Mechanical Engineers (ASME), Fluids Engineering

  15. Department of Mechanical and

    E-Print Network [OSTI]

    Huang, Jianwei

    Department of Mechanical and Automation Engineering #12;4 2 3 1 Contents Messages in the souvenir publication of the Department of Mechanical and Automation Engineering of The Chinese University of Mechanical and Automation Engineering have also played a significant part in equipping businesses

  16. Mechanical & Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical & Aerospace Engineering Much of past research in structural dynamics (and many other the University of Liege, Belgium, in 1983 and his Ph.D. in mechanical engineering from Rice University in 1987. He then joined the rather newly formed Department of Mechanical and Aerospace Engineering at ASU

  17. TOWARDS MECHANICAL METAMATHEMATICS

    E-Print Network [OSTI]

    Boyer, Robert Stephen

    TOWARDS MECHANICAL METAMATHEMATICS N. Shankar Technical Report 43 December 1984 Institute application of certain mechanical rules of inference. The derivations of theorems from the axioms are termed of a valid mathematical argument. Another advantage of formal proofs is that they can be mechanically checked

  18. Mechanical & Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical & Aerospace Engineering It has been demonstrated that the color pattern of the human received the B.A. degree in physics from Houghton College, Houghton, NY, and the B.S. degree in mechanical in mechanical engineering from the Massachusetts Institute of Technology (MIT), Cambridge, MA, in 1997 and 2002

  19. A mechanical encapsulatio n

    E-Print Network [OSTI]

    Jackson, Trachette L.

    A mechanical mo delo f tumo r encapsulatio n and transcapsular spread Trachette L. Jackso n a 48109≠1109, USA b Division of Theoretical Mechanics, School of Mathematical Sciences, University rmatio n, such investigatio ns being ideally suited to o ur mechanical mo del. The mo del simulatio ns

  20. Mechanical & Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical & Aerospace Engineering Fragmentation is a process in which structures fail in a very Engineering at Duke University, where he directs the Duke Computational Mechanics Laboratory. Professor Dolbow received his BS in Mechanical Engineering from the University of New Hampshire in 1995, and his Ph

  1. Mechanical & Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical & Aerospace Engineering The miniaturization of structural components to the sub progress in strain-gradient continuum theories to model the mechanical behavior of metallic systems at small length scales, these theories fail to represent the variety of physical mechanisms involved

  2. Mechanical Engineering Assistant Professor

    E-Print Network [OSTI]

    Chandy, John A.

    Mechanical Engineering Xu Chen Assistant Professor xchen@uconn.edu http://xchen.lab.uconn.edu From Engineering Ingredients of Kung Pao Chicken Marinade ∑ 1 tablespoon soy sauce ∑ 2 teaspoons Chinese rice wine of Diana Kuan #12;Mechanical Engineering The Cooking Procedure #12;Mechanical Engineering The Difference

  3. Mechanical & Industrial Engineering

    E-Print Network [OSTI]

    Mountziaris, T. J.

    Mechanical & Industrial Engineering Mario A. Rotea Professor and Department Head #12;2Mechanical & Industrial Engineering Outline ∑ Undergraduate Degree Programs ∑ Graduate Degree Programs ∑ The Faculty ∑ The Research ∑ Summary #12;3Mechanical & Industrial Engineering Undergraduate Programs ≠ BSME & BSIE 0 20 40 60

  4. Mechanical & Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical & Aerospace Engineering Pool boiling heat transfer enhancement is taking a dramatic turn Mechanical Engineering Rochester Institute of Technology September 5, 2014 at 1:30pm in SCOB 210 School from the classical area enhancement and nucleation cavity augmentation to mechanism based

  5. Mechanical & Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical & Aerospace Engineering Energetic materials that include nano-scale aluminum (Al and joined the faculty in the Mechanical Engineering Department at Texas Tech University in 2000 Pantoya Dept. of Mechanical Engineering Texas Tech University April 19, 2013 at 1:30pm in LSE 106 School

  6. Mechanical & Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical & Aerospace Engineering The presentation will first review emerging joint time in Mechanical Engineering and Engineering Science from the Technical University in Athens, Greece and his, vehicle engineering, bio-mechanics, and composite materials. He is Editor-in-Chief of the International

  7. Mechanical & Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical & Aerospace Engineering The state of the art in Quantification of Margin and UncertaintyD in Engineering Mechanics from the University of Wisconsin in 1978. He then worked in research laboratories of the University of Wisconsin as a Senior Scientist. In March of this year, he joined the Mechanical Engineering

  8. Mechanical and Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical and Aerospace Engineering seminar From Jumping Drops to Thermal Diodes Abstract Scholar and Assistant Professor of Mechanical Engineering and Materials Science at Duke University since.D. degree in Mechanical Engineering from Stanford University (2004). Dr. Chen is a recipient of numerous

  9. Mechanical and Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical and Aerospace Engineering seminar Some Forward-Looking Assistive Devices to Improve. Biosketch Michael Goldfarb, PhD, is the H. Fort Flowers Professor of Mechanical Engineering and the director in Mechanical Engineering from the University of Arizona in 1988, and received his SM and PhD degrees

  10. Mechanical and Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical and Aerospace Engineering seminar Plasma Actuators for Aerodynamic Flow Control.D. in Mechanical Engineering from The Ohio State University in 2004, 2005 and 2010 respectively. He joined the Department of Aerospace and Mechanical Engineering at the University of Arizona in 2010 as an Assistant

  11. Mechanical & Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical & Aerospace Engineering The atomization of a liquid jet by a high speed cross.S.E. degree in mechanical engineering from Amirkabir University of Technology in 2006 and M.S. degree in mechanical engineering from Sharif University of Technology in 2009. He is currently a Ph.D. candidate

  12. QUICK QUANTUM MECHANICS ---Introduction ---

    E-Print Network [OSTI]

    Jackson, Andrew D.

    QUICK QUANTUM MECHANICS --- Introduction --- The following notes are intended to be a supplement to your study of Liboff's ``Introductory Quantum Mechanics.'' They are not an alternative! My purpose here of Classical Mechanics After Newton found his equations of motion, physicists knew they would have to wait

  13. Introduction to Quantum Mechanics

    E-Print Network [OSTI]

    Eduardo J. S. VillaseŮor

    2008-04-23

    The purpose of this contribution is to give a very brief introduction to Quantum Mechanics for an audience of mathematicians. I will follow Segal's approach to Quantum Mechanics paying special attention to algebraic issues. The usual representation of Quantum Mechanics on Hilbert spaces is also discussed.

  14. Mechanical Systems Signal Processing

    E-Print Network [OSTI]

    Carvalho, Jo„o B.

    , Northern Illinois University, DeKalb, IL 60115, USA c Department of Mechanical Engineering & VibrationMechanical Systems and Signal Processing Mechanical Systems and Signal Processing 21 (2007) 2715 Federal de Rio Grande do Sul, Brazil b Department of Mathematical Sciences & Vibration and Acoustic Center

  15. Mathematical Problems of Thermoacoustic Tomography†

    E-Print Network [OSTI]

    Nguyen, Linh V.

    2010-10-12

    Thermoacoustic tomography (TAT) is a newly emerging modality in biomedical imaging. It combines the good contrast of electromagnetic and good resolution of ultrasound imaging. The mathematical model of TAT is the observability problem for the wave...

  16. Surrogate Guderley Test Problem Definition

    SciTech Connect (OSTI)

    Ramsey, Scott D. [Los Alamos National Laboratory; Shashkov, Mikhail J. [Los Alamos National Laboratory

    2012-07-06

    The surrogate Guderley problem (SGP) is a 'spherical shock tube' (or 'spherical driven implosion') designed to ease the notoriously subtle initialization of the true Guderley problem, while still maintaining a high degree of fidelity. In this problem (similar to the Guderley problem), an infinitely strong shock wave forms and converges in one-dimensional (1D) cylindrical or spherical symmetry through a polytropic gas with arbitrary adiabatic index {gamma}, uniform density {rho}{sub 0}, zero velocity, and negligible pre-shock pressure and specific internal energy (SIE). This shock proceeds to focus on the point or axis of symmetry at r = 0 (resulting in ostensibly infinite pressure, velocity, etc.) and reflect back out into the incoming perturbed gas.

  17. Galois Groups of Schubert Problems

    E-Print Network [OSTI]

    Martin Del Campo Sanchez, Abraham

    2012-10-19

    The Galois group of a Schubert problem is a subtle invariant that encodes intrinsic structure of its set of solutions. These geometric invariants are difficult to determine in general. However, based on a special position argument due to Schubert...

  18. SOME COMPUTATIONAL PROBLEMS IN MICROFLUIDICS.

    E-Print Network [OSTI]

    Colin, Thierry

    SOME COMPUTATIONAL PROBLEMS IN MICROFLUIDICS. S. Tancogne, Ch.-H. Bruneau, Th. Colin Institut de is to present some results of flow simulations in microflu- idics. Microfluidics is characterized

  19. Exemption from Application of the Service Contract Act -Requirements UT-B Contracts Div Maintenance, Calibration, or Repair of Certain Equipment

    E-Print Network [OSTI]

    Maintenance, Calibration, or Repair of Certain Equipment Jan 2008 Page 1 of 1 exemp-sca-equip-requirement-ext-jan08.doc EXEMPTION FROM APPLICATION OF THE SERVICE CONTRACT ACT ≠ MAINTENANCE, CALIBRATION, OR REPAIR quantities to the general public in the course of normal business operations. (b) The services shall

  20. Exemption from Application of the Service Contract Act -Certification UT-B Contracts Div Maintenance, Calibration, or Repair of Certain Equipment

    E-Print Network [OSTI]

    Maintenance, Calibration, or Repair of Certain Equipment Mar 2009 Page 1 of 1 exemp-sca-equip-certification-ext-venx-mar09.doc EXEMPTION FROM APPLICATION OF THE SERVICE CONTRACT ACT ≠ MAINTENANCE, CALIBRATION, OR REPAIR in the course of normal business operations. (2) The services will be furnished at prices which are

  1. Current problems in plasma spray processing

    SciTech Connect (OSTI)

    Berndt, C.C.; Brindley, W.; Goland, A.N.; Herman, H.; Houck, D.L.; Jones, K.; Miller, R.A.; Neiser, R.; Riggs, W.; Sampath, S.; Smith, M.; Spanne, P.

    1991-12-31

    This detailed report summarizes 8 contributions from a thermal spray conference that was held in late 1991 at Brookhaven National Laboratory (Upton, Long Island, NY, USA). The subject of ``Plasma Spray Processing`` is presented under subject headings of Plasma-particle interactions, Deposit formation dynamics, Thermal properties of thermal barrier coatings, Mechanical properties of coatings, Feed stock materials, Porosity: An integrated approach, Manufacture of intermetallic coatings, and Synchrotron x-ray microtomographic methods for thermal spray materials. Each section is intended to present a concise statement of a specific practical and/or scientific problem, then describe current work that is being performed to investigate this area, and finally to suggest areas of research that may be fertile for future activity.

  2. Current problems in plasma spray processing

    SciTech Connect (OSTI)

    Berndt, C.C.; Brindley, W.; Goland, A.N.; Herman, H.; Houck, D.L.; Jones, K.; Miller, R.A.; Neiser, R.; Riggs, W.; Sampath, S.; Smith, M.; Spanne, P. . Thermal Spray Lab.)

    1991-01-01

    This detailed report summarizes 8 contributions from a thermal spray conference that was held in late 1991 at Brookhaven National Laboratory (Upton, Long Island, NY, USA). The subject of Plasma Spray Processing'' is presented under subject headings of Plasma-particle interactions, Deposit formation dynamics, Thermal properties of thermal barrier coatings, Mechanical properties of coatings, Feed stock materials, Porosity: An integrated approach, Manufacture of intermetallic coatings, and Synchrotron x-ray microtomographic methods for thermal spray materials. Each section is intended to present a concise statement of a specific practical and/or scientific problem, then describe current work that is being performed to investigate this area, and finally to suggest areas of research that may be fertile for future activity.

  3. Seismic Performance Assessment and Probabilistic Repair Cost Analysis of Precast Concrete Cladding Systems for Multistory Buildings

    E-Print Network [OSTI]

    Hunt, Jeffrey Patrick

    2010-01-01

    be analyzed as a support movement problem gap bolt Fig. 6.7support movement problem .. 176 Fig. 6.7 Movement of the connector boltsupport movement due to spandrel panel rotation and story shortening gap ? h bolt

  4. Mechanical seal assembly

    DOE Patents [OSTI]

    Kotlyar, Oleg M. (Salt Lake City, UT)

    2002-01-01

    An improved mechanical seal assembly is provided for sealing rotating shafts with respect to their shaft housings, wherein the rotating shafts are subject to substantial axial vibrations. The mechanical seal assembly generally includes a rotating sealing ring fixed to the shaft, a non-rotating sealing ring adjacent to and in close contact with the rotating sealing ring for forming an annular seal about the shaft, and a mechanical diode element that applies a biasing force to the non-rotating sealing ring by means of hemispherical joint. The alignment of the mechanical diode with respect to the sealing rings is maintained by a series of linear bearings positioned axially along a desired length of the mechanical diode. Alternative embodiments include mechanical or hydraulic amplification components for amplifying axial displacement of the non-rotating sealing ring and transfering it to the mechanical diode.

  5. Mechanical seal assembly

    DOE Patents [OSTI]

    Kotlyar, Oleg M. (Salt Lake City, UT)

    2001-01-01

    An improved mechanical seal assembly is provided for sealing rotating shafts with respect to their shaft housings, wherein the rotating shafts are subject to substantial axial vibrations. The mechanical seal assembly generally includes a rotating sealing ring fixed to the shaft, a non-rotating sealing ring adjacent to and in close contact with the rotating sealing ring for forming an annular seal about the shaft, and a mechanical diode element that applies a biasing force to the non-rotating sealing ring by means of hemispherical joint. The alignment of the mechanical diode with respect to the sealing rings is maintained by a series of linear bearings positioned axially along a desired length of the mechanical diode. Alternative embodiments include mechanical or hydraulic amplification components for amplifying axial displacement of the non-rotating sealing ring and transferring it to the mechanical diode.

  6. Mechanism Design and Implementation for Lung Exchange Suiqian Luo and Pingzhong Tang

    E-Print Network [OSTI]

    Tang, Pingzhong

    Mechanism Design and Implementation for Lung Exchange Suiqian Luo and Pingzhong Tang Institute@tsinghua.edu.cn Abstract We explore the mechanism design problem for lung exchange and its implementation in practice. We prove that determining whether there exists a non- trivial solution of the lung exchange problem is NP

  7. Nikon Instruments Inc. | Resource Center -Research Papers -New insights into DNA repair http://www.nikoninstruments.com/Resource-Center/Research-Papers/New-insights-into-DNA-repair[4/10/2012 10:42:30 AM

    E-Print Network [OSTI]

    Kowalczykowski, Stephen C.

    Nikon Instruments Inc. | Resource Center - Research Papers - New insights into DNA repair http:42:30 AM] change locationAMS EN Nikon Instruments Inc. on Facebook Like You like th Page ∑ Ins Resource constrain available 3D conformations and slow the rate of homologous pairing while longer ssDNA strands

  8. Part of the Climate Change Problem . . . and the Solution? Chinese-Made Wind Power Technology and Opportunities for Dissemination

    E-Print Network [OSTI]

    Lewis, Joanna I.

    2005-01-01

    to† supply† mainland. Ē† Windpower† Monthly,† October† 14 †Horns† Reef† repairs. Ē† Windpower† Monthly. † November,†

  9. A MONOTONE MULTIGRID SOLVER FOR TWO BODY CONTACT PROBLEMS IN BIOMECHANICS

    E-Print Network [OSTI]

    Kornhuber, Ralf

    A MONOTONE MULTIGRID SOLVER FOR TWO BODY CONTACT PROBLEMS IN BIOMECHANICS R. KORNHUBER, R. KRAUSE meth≠ ods to static and dynamic biomechanical contact problems. In space, a finite element method and a biomechanical application are reported. 1. Introduction Mechanical loading in human joints plays a crucial role

  10. The problem of non-renewable energy resources in the production of physical capital

    E-Print Network [OSTI]

    Nesterov, Yurii

    2007/8 The problem of non-renewable energy resources in the production of physical capital Agustin Pťrez-Barahona #12;CORE DISCUSSION PAPER 2007/8 The problem of non-renewable energy resources-run growth, although energy is produced by means of non-renewable energy resources. The mechanism behind

  11. PROBLEMS

    E-Print Network [OSTI]

    According to the elementary laws of electricity, we know that. The voltage drop across the resistor is IR. The voltage drop across the capacitor is Q/ C.

  12. Problem

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    were created by combining evaporation-induced self- assembly of nanopores with atomic layer deposition (ALD), allowing specific tuning of both pore size and surface chemistry. By...

  13. Problem

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    process takes place at room temperature using ambient conditions, yet produces a coating competitive with current technologies. Innovative Edge Sandia's method for applying...

  14. Problem

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration wouldMass mapSpeedingProgramExemptions | National NuclearProbingProbing metal solidificationTech

  15. Problem

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration wouldMass mapSpeedingProgramExemptions | National NuclearProbingProbing metal

  16. Problem

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home RoomPreservation of Fe(II) by Carbon-Rich Matrices inPrincipalFirm Exchange . . .Probing

  17. Problem

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home RoomPreservation of Fe(II) by Carbon-Rich Matrices inPrincipalFirm Exchange . . .ProbingTech

  18. Black Hole Thermodynamics and Statistical Mechanics

    E-Print Network [OSTI]

    Steven Carlip

    2008-07-28

    We have known for more than thirty years that black holes behave as thermodynamic systems, radiating as black bodies with characteristic temperatures and entropies. This behavior is not only interesting in its own right; it could also, through a statistical mechanical description, cast light on some of the deep problems of quantizing gravity. In these lectures, I review what we currently know about black hole thermodynamics and statistical mechanics, suggest a rather speculative "universal" characterization of the underlying states, and describe some key open questions.

  19. CrowdPhase: crowdsourcing the phase problem

    SciTech Connect (OSTI)

    Jorda, Julien; Sawaya, Michael R. [Institute for Genomics and Proteomics, 611 Charles Young Drive East, Los Angeles, CA 90095 (United States); Yeates, Todd O., E-mail: yeates@mbi.ucla.edu [Institute for Genomics and Proteomics, 611 Charles Young Drive East, Los Angeles, CA 90095 (United States); Molecular Biology Institute, 611 Charles Young Drive East, Los Angeles, CA 90095 (United States); University of California, 611 Charles Young Drive East, Los Angeles, CA 90095 (United States)

    2014-06-01

    The idea of attacking the phase problem by crowdsourcing is introduced. Using an interactive, multi-player, web-based system, participants work simultaneously to select phase sets that correspond to better electron-density maps in order to solve low-resolution phasing problems. The human mind innately excels at some complex tasks that are difficult to solve using computers alone. For complex problems amenable to parallelization, strategies can be developed to exploit human intelligence in a collective form: such approaches are sometimes referred to as Ďcrowdsourcingí. Here, a first attempt at a crowdsourced approach for low-resolution ab initio phasing in macromolecular crystallography is proposed. A collaborative online game named CrowdPhase was designed, which relies on a human-powered genetic algorithm, where players control the selection mechanism during the evolutionary process. The algorithm starts from a population of Ďindividualsí, each with a random genetic makeup, in this case a map prepared from a random set of phases, and tries to cause the population to evolve towards individuals with better phases based on Darwinian survival of the fittest. Players apply their pattern-recognition capabilities to evaluate the electron-density maps generated from these sets of phases and to select the fittest individuals. A user-friendly interface, a training stage and a competitive scoring system foster a network of well trained players who can guide the genetic algorithm towards better solutions from generation to generation via gameplay. CrowdPhase was applied to two synthetic low-resolution phasing puzzles and it was shown that players could successfully obtain phase sets in the 30į phase error range and corresponding molecular envelopes showing agreement with the low-resolution models. The successful preliminary studies suggest that with further development the crowdsourcing approach could fill a gap in current crystallographic methods by making it possible to extract meaningful information in cases where limited resolution might otherwise prevent initial phasing.

  20. MA69400 Obstacle Type Problems

    E-Print Network [OSTI]

    Aug 23, 2010 ... transitions and fluid mechanics. ... The objective in this course is to give an introduction to the theory of ... classification of global solutions, geometric and energy criterions for the regularity of the free boundary, singular points.

  1. Published on Science 2.0 (http://www.science20.com) Home > Life Sciences > Genetics & Molecular Biology > News Articles > Rad51: Watching Single Strands Of DNA Being Prepped For Repair Could Help Fight Breast Cancer

    E-Print Network [OSTI]

    Kowalczykowski, Stephen C.

    Biology > News Articles > Rad51: Watching Single Strands Of DNA Being Prepped For Repair Could Help Fight Breast Cancer Rad51: Watching Single Strands Of DNA Being Prepped For Repair Could Help Fight Breast: Watching Single Strands Of DNA Being Prepped For Repair Could Help Fight Br... 6/17/2013http

  2. Solving the Tulsa ozone problem

    SciTech Connect (OSTI)

    Wagner, K.K. [Atmospheric Information Systems, Norman, OK (United States); Wilson, J.D. [Wilson Consulting Group, Tulsa, OK (United States); Gibeau, E. [Aeromet Inc., Tulsa, OK (United States)

    1998-12-31

    Local governments and interested parties in Tulsa, Oklahoma are planning actions to keep Tulsa in compliance with the ozone ambient air quality standard. Based on recent data Tulsa exceeds the new eight hour average national ambient air quality standard for ozone and occasionally exceeds the previous one hour standard. Currently, Tulsa is in attainment of the former one-hour ozone standard. The first planning step is to integrate the existing information about Tulsa`s ozone problem. Prior studies of Tulsa ozone are reviewed. Tulsa`s recent air quality and meteorological monitoring are evaluated. Emission inventory estimates are assessed. Factors identified with Tulsa`s ozone problem are the transport of ozone and precursor gases, a possible role for biogenic emissions, and a simplistic ozone forecasting method. The integration of information found that current air quality and meteorological monitoring is meager. Observations of volatile organic compounds and NO{sub y} are absent. Prior intensive studies in 1977 and 1985 are more than ten years old and lack relevance to today`s problem. Emission inventory estimates are scarce and uncertain. The current knowledge base was judged inadequate to properly characterize the present ozone problem. Actions are recommended to enlarge the information base to address Tulsa`s ozone problem.

  3. Drilling and Microfracture Lead to Different Bone Structure and Necrosis during Bone-Marrow Stimulation for Cartilage Repair

    E-Print Network [OSTI]

    Buschmann, Michael

    Drilling and Microfracture Lead to Different Bone Structure and Necrosis during Bone following microfracture and comparing to drilling in a mature rabbit model of cartilage repair. Microfracture holes were made to a depth of 2 mm and drill holes to either 2 mm or 6 mm under cooled irrigation

  4. Image-Guided Techniques Improve the Short-term Outcome of Autologous Osteochondral Cartilage Repair Surgeries -An

    E-Print Network [OSTI]

    Stewart, James

    Image-Guided Techniques Improve the Short-term Outcome of Autologous Osteochondral Cartilage Repair and deliver osteochondral grafts remains problematic. We investigated whether image-guided methods (optically-guided and template-guided) can improve the outcome of mo- saic arthroplasty procedures. Methods: Fifteen sheep were

  5. Homologous recombination contributes to the repair of DNA double-strand breaks induced by high-energy iron ions

    SciTech Connect (OSTI)

    Zafar, Faria; Seidler, Sara B.; Kronenberg, Amy; Schild, David; Wiese, Claudia

    2010-06-29

    To test the contribution of homologous recombinational repair (HRR) in repairing DNA damaged sites induced by high-energy iron ions, we used: (1) HRR-deficient rodent cells carrying a deletion in the RAD51D gene and (2) syngeneic human cells impaired for HRR by RAD51D or RAD51 knockdown using RNA interference. We show that in response to iron ions, HRR contributes to cell survival in rodent cells, and that HRR-deficiency abrogates RAD51 foci formation. Complementation of the HRR defect by human RAD51D rescues both enhanced cytotoxicity and RAD51 foci formation. For human cells irradiated with iron ions, cell survival is decreased, and, in p53 mutant cells, the levels of mutagenesis are increased when HRR is impaired. Human cells synchronized in S phase exhibit more pronounced resistance to iron ions as compared with cells in G1 phase, and this increase in radioresistance is diminished by RAD51 knockdown. These results implicate a role for RAD51-mediated DNA repair (i.e. HRR) in removing a fraction of clustered lesions induced by charged particle irradiation. Our results are the first to directly show the requirement for an intact HRR pathway in human cells in ensuring DNA repair and cell survival in response to high-energy high LET radiation.

  6. Direct observations of DNA provides new insights into how genetic material is copied and repaired News-Medical.Net

    E-Print Network [OSTI]

    Kowalczykowski, Stephen C.

    Direct observations of DNA provides new insights into how genetic material is copied and repaired News-Medical.Net ∑ Home Page Direct observations of DNA provides new insights into how genetic material to a Friend Direct observations of DNA are giving new insights into how genetic material is copied

  7. Global-to-Local Rule Generation for Self-Assembly and Self-Repair by Robot Swarms

    E-Print Network [OSTI]

    Southern California, University of

    Global-to-Local Rule Generation for Self-Assembly and Self-Repair by Robot Swarms Daniel Arbuckle a reactive self-assembly technique intended for use in swarms of simple robots, the other a distributed in the possibility that swarms of general-purpose self-assembling robots might be used to replace many such objects

  8. International Journal of Adhesion & Adhesives 26 (2006) 314324 Dynamic response of a repaired composite beam with an adhesively

    E-Print Network [OSTI]

    Vaziri, Ashkan

    2006-01-01

    International Journal of Adhesion & Adhesives 26 (2006) 314≠324 Dynamic response of a repaired composite beam with an adhesively bonded patch under a harmonic peeling load A. Vaziri1 , H. Nayeb with adhesive. In the theoretical part, the equations of motion in the axial and transverse directions were

  9. Charge-transport-mediated recruitment of DNA repair enzymes Pak-Wing Fok,1,2,a

    E-Print Network [OSTI]

    Levine, Alex J.

    Charge-transport-mediated recruitment of DNA repair enzymes Pak-Wing Fok,1,2,a Chin-Lin Guo,3 and Tom Chou2,4,b 1 Applied and Computational Mathematics, California Institute of Technology, Pasadena, California 91125, USA 2 Department of Biomathematics, UCLA, Los Angeles, California 90095-1766, USA 3 Applied

  10. Dynamics-dependent symmetries in Newtonian mechanics

    E-Print Network [OSTI]

    Peter Holland

    2014-09-19

    We exhibit two symmetries of one-dimensional Newtonian mechanics whereby a solution is built from the history of another solution via a generally nonlinear and complex potential-dependent transformation of the time. One symmetry intertwines the square roots of the kinetic and potential energies and connects solutions of the same dynamical problem (the potential is an invariant function). The other symmetry connects solutions of different dynamical problems (the potential is a scalar function). The existence of corresponding conserved quantities is examined using Noethers theorem and it is shown that the invariant-potential symmetry is correlated with energy conservation. In the Hamilton-Jacobi picture the invariant-potential transformation provides an example of a field-dependent symmetry in point mechanics. It is shown that this transformation is not a symmetry of the Schroedinger equation.

  11. Fractional Classical Mechanics

    E-Print Network [OSTI]

    Nick Laskin

    2013-02-03

    Fractional classical mechanics has been introduced and developed as a classical counterpart of the fractional quantum mechanics. Lagrange, Hamilton and Hamilton-Jacobi frameworks have been implemented for the fractional classical mechanics. The Lagrangian of fractional classical mechanics has been introduced, and equation of motion has been obtained. Fractional oscillator model has been launched and solved in 1D case. A new equation for the period of oscillations of fractional classical oscillator has been found. The interplay between the energy dependency of the period of classical oscillations and the non-equidistant distribution of the energy levels for fractional quantum oscillator has been discussed. We discuss as well, the relationships between new equations of fractional classical mechanics and the well-known fundamental equations of classical mechanics.

  12. Method and apparatus for in-system redundant array repair on integrated circuits

    DOE Patents [OSTI]

    Bright, Arthur A. (Croton-on-Hudson, NY); Crumley, Paul G. (Yorktown Heights, NY); Dombrowa, Marc B. (Bronx, NY); Douskey, Steven M. (Rochester, MN); Haring, Rudolf A. (Cortlandt Manor, NY); Oakland, Steven F. (Colchester, VT); Ouellette, Michael R. (Westford, VT); Strissel, Scott A. (Byron, MN)

    2008-07-08

    Disclosed is a method of repairing an integrated circuit of the type comprising of a multitude of memory arrays and a fuse box holding control data for controlling redundancy logic of the arrays. The method comprises the steps of providing the integrated circuit with a control data selector for passing the control data from the fuse box to the memory arrays; providing a source of alternate control data, external of the integrated circuit; and connecting the source of alternate control data to the control data selector. The method comprises the further step of, at a given time, passing the alternate control data from the source thereof, through the control data selector and to the memory arrays to control the redundancy logic of the memory arrays.

  13. Method and apparatus for in-system redundant array repair on integrated circuits

    DOE Patents [OSTI]

    Bright, Arthur A. (Croton-on-Hudson, NY); Crumley, Paul G. (Yorktown Heights, NY); Dombrowa, Marc B. (Bronx, NY); Douskey, Steven M. (Rochester, MN); Haring, Rudolf A. (Cortlandt Manor, NY); Oakland, Steven F. (Colchester, VT); Ouellette, Michael R. (Westford, VT); Strissel, Scott A. (Byron, MN)

    2007-12-18

    Disclosed is a method of repairing an integrated circuit of the type comprising of a multitude of memory arrays and a fuse box holding control data for controlling redundancy logic of the arrays. The method comprises the steps of providing the integrated circuit with a control data selector for passing the control data from the fuse box to the memory arrays; providing a source of alternate control data, external of the integrated circuit; and connecting the source of alternate control data to the control data selector. The method comprises the further step of, at a given time, passing the alternate control data from the source thereof, through the control data selector and to the memory arrays to control the redundancy logic of the memory arrays.

  14. Method and apparatus for in-system redundant array repair on integrated circuits

    DOE Patents [OSTI]

    Bright, Arthur A. (Croton-on-Hudson, NY); Crumley, Paul G. (Yorktown Heights, NY); Dombrowa, Marc B. (Bronx, NY); Douskey, Steven M. (Rochester, MN); Haring, Rudolf A. (Cortlandt Manor, NY); Oakland, Steven F. (Colchester, VT); Ouellette, Michael R. (Westford, VT); Strissel, Scott A. (Byron, MN)

    2008-07-29

    Disclosed is a method of repairing an integrated circuit of the type comprising of a multitude of memory arrays and a fuse box holding control data for controlling redundancy logic of the arrays. The method comprises the steps of providing the integrated circuit with a control data selector for passing the control data from the fuse box to the memory arrays; providing a source of alternate control data, external of the integrated circuit; and connecting the source of alternate control data to the control data selector. The method comprises the further step of, at a given time, passing the alternate control data from the source thereof, through the control data selector and to the memory arrays to control the redundancy logic of the memory arrays.

  15. Design structure for in-system redundant array repair in integrated circuits

    DOE Patents [OSTI]

    Bright, Arthur A.; Crumley, Paul G.; Dombrowa, Marc; Douskey, Steven M.; Haring, Rudolf A.; Oakland, Steven F.; Quellette, Michael R.; Strissel, Scott A.

    2008-11-25

    A design structure for repairing an integrated circuit during operation of the integrated circuit. The integrated circuit comprising of a multitude of memory arrays and a fuse box holding control data for controlling redundancy logic of the arrays. The design structure provides the integrated circuit with a control data selector for passing the control data from the fuse box to the memory arrays; providing a source of alternate control data, external of the integrated circuit; and connecting the source of alternate control data to the control data selector. The design structure further passes the alternate control data from the source thereof, through the control data selector and to the memory arrays to control the redundancy logic of the memory arrays.

  16. Mechanical Model for Relativistic Blast Waves

    E-Print Network [OSTI]

    A. M. Beloborodov; Z. L. Uhm

    2006-09-02

    Relativistic blast waves can be described by a mechanical model. In this model, the "blast" -- the compressed gas between the forward and reverse shocks -- is viewed as one hot body. Equations governing its dynamics are derived from conservation of mass, energy, and momentum. Simple analytical solutions are obtained in the two limiting cases of ultra-relativistic and non-relativistic reverse shock. Equations are derived for the general explosion problem.

  17. Distinct kinetics of human DNA ligases I, IIIalpha, IIIbeta, and IV reveal direct DNA sensing ability and differential physiological functions in DNA repair

    SciTech Connect (OSTI)

    Chen, Xi; Ballin, Jeff D.; Della-Maria, Julie; Tsai, Miaw-Sheue; White, Elizabeth J.; Tomkinson, Alan E.; Wilson, Gerald M.

    2009-05-11

    The three human LIG genes encode polypeptides that catalyze phosphodiester bond formation during DNA replication, recombination and repair. While numerous studies have identified protein partners of the human DNA ligases (hLigs), there has been little characterization of the catalytic properties of these enzymes. In this study, we developed and optimized a fluorescence-based DNA ligation assay to characterize the activities of purified hLigs. Although hLigI joins DNA nicks, it has no detectable activity on linear duplex DNA substrates with short, cohesive single-strand ends. By contrast, hLigIII{beta} and the hLigIII{alpha}/XRCC1 and hLigIV/XRCC4 complexes are active on both nicked and linear duplex DNA substrates. Surprisingly, hLigIV/XRCC4, which is a key component of the major non-homologous end joining (NHEJ) pathway, is significantly less active than hLigIII on a linear duplex DNA substrate. Notably, hLigIV/XRCC4 molecules only catalyze a single ligation event in the absence or presence of ATP. The failure to catalyze subsequent ligation events reflects a defect in the enzyme-adenylation step of the next ligation reaction and suggests that, unless there is an in vivo mechanism to reactivate DNA ligase IV/XRCC4 following phosphodiester bond formation, the cellular NHEJ capacity will be determined by the number of adenylated DNA ligaseIV/XRCC4 molecules.

  18. Mechanical Properties of Nanocrystal Supercrystals

    E-Print Network [OSTI]

    Tam, Enrico

    2010-01-01

    and Its Impact on Mechanical Properties. MacromoleculesO. L. ; Minor, A. M. , Mechanical annealing and source-Mechanical Properties of Nanocrystal Supercrystals Enrico

  19. Statistical mechanics of the cytoskeleton

    E-Print Network [OSTI]

    Wang, Shenshen

    2012-01-01

    mechanics . . . . . . . . . . . . . . . . . . . . . . 2.1bottom-up approach to cell mechanics. Nat. Phys. [6] Fabry,Wolynes, P. G. Statistical mechanics of a catís cradle. New

  20. Hard Evidence and Mechanism Design

    E-Print Network [OSTI]

    Watson, Joel; Bull, Jesse

    2006-01-01

    J. , 2003. Contract, mechanism design, and technologicalSeverinov, S. , 2001. Mechanism design and communicationveri?able information and mechanism design. Rev. Econ. Stud.

  1. Hard Evidence and Mechanism Design

    E-Print Network [OSTI]

    Bull, J; Watson, J

    2007-01-01

    J. , 2003. Contract, mechanism design, and technologicalSeverinov, S. , 2001. Mechanism design and communicationveri?able information and mechanism design. Rev. Econ. Stud.

  2. Quantum algorithms for algebraic problems

    E-Print Network [OSTI]

    Andrew M. Childs; Wim van Dam

    2008-12-02

    Quantum computers can execute algorithms that dramatically outperform classical computation. As the best-known example, Shor discovered an efficient quantum algorithm for factoring integers, whereas factoring appears to be difficult for classical computers. Understanding what other computational problems can be solved significantly faster using quantum algorithms is one of the major challenges in the theory of quantum computation, and such algorithms motivate the formidable task of building a large-scale quantum computer. This article reviews the current state of quantum algorithms, focusing on algorithms with superpolynomial speedup over classical computation, and in particular, on problems with an algebraic flavor.

  3. The Duhem-Quine thesis and the dark matter problem

    E-Print Network [OSTI]

    Reynolds, M A

    2015-01-01

    There are few opportunities in introductory physics for a genuine discussion of the philosophy of science, especially in cases where the physical principles are straightforward and the mathematics is simple. Terrestrial classical mechanics satisfies these requirements, but students new to physics usually carry too many incorrect or misleading preconceptions about the subject for it to be analyzed epistemologically. The problem of dark matter, and especially the physics of spiral galaxy velocity rotation curves, is a straightforward application of Newton's laws of motion and gravitation, and is just enough removed from everyday experience to be analyzed from a fresh perspective. It is proposed to teach students about important issues in the philosophy of physics, including Bacon's induction, Popper's falsifiability, and the Duhem-Quine thesis, all in light of the dark matter problem. These issues can be discussed in an advanced classical mechanics course, or, with limited simplification, at the end of a first ...

  4. Kinetic gating mechanism of DNA damage recognition by Rad4/XPC

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Chen, Xuejing; Velmurugu, Yogambigai; Zheng, Guanqun; Park, Beomseok; Shim, Yoonjung; Kim, Youngchang; Liu, Lili; Van Houten, Bennett; He, Chuan; Ansari, Anjum; et al

    2015-01-06

    The xeroderma pigmentosum C (XPC) complex initiates nucleotide excision repair by recognizing DNA lesions before recruiting downstream factors. How XPC detects structurally diverse lesions embedded within normal DNA is unknown. Here we present a crystal structure that captures the yeast XPC orthologue (Rad4) on a single register of undamaged DNA. The structure shows that a disulphide-tethered Rad4 flips out normal nucleotides and adopts a conformations similar to that seen with damaged DNA. Contrary to many DNA repair enzymes that can directly reject non-target sites as structural misfits, our results suggest that Rad4/XPC uses a kinetic gating mechanism whereby lesion selectivitymore†Ľarises from the kinetic competition between DNA opening and the residence time of Rad4/XPC per site. This mechanism is further supported by measurements of Rad4-induced lesion-opening times using temperature-jump pertubation spectroscopy. Kinetic gating may be a general mechanism used by site-specific DNA-binding proteins to minimize time-consuming interrogations of non-target sites.ę†less

  5. Mechanical & Aerospace Engineering

    E-Print Network [OSTI]

    Mechanical & Aerospace Engineering The development of high-energy storage devices has been one in portable electronic devices, satellites, and electric vehicles. Silicon (Si) is an attractive anode

  6. Applied quantum mechanics 1 Applied Quantum Mechanics

    E-Print Network [OSTI]

    Levi, Anthony F. J.

    -linear recombination coefficient C 5 10 29≠ cm 6 s 1≠ = , a bulk gain model with optical transparency at carrier equations using the same device parameters as in Exercise 9.4, but with a 1 ns round-trip photon delay from) = 20 mA Lens 100% reflecting mirror Light path with 1 ns round-trip time Problem 9.5 The probability

  7. Tensile strengths of problem shales and clays. Master's thesis

    SciTech Connect (OSTI)

    Rechner, F.J.

    1990-01-01

    The greatest single expense faced by oil companies involved in the exploration for crude oil is that of drilling wells. The most abundant rock drilled is shale. Some of these shales cause wellbore stability problems during the drilling process. These can range from slow rate of penetration and high torque up to stuck pipe and hole abandonment. The mechanical integrity of the shale must be known when the shalers are subjected to drilling fluids to develop an effective drilling plan.

  8. Emerging Trends in Heart Valve Engineering: Part III. Novel Technologies for Mitral Valve Repair and Replacement

    E-Print Network [OSTI]

    2015-01-01

    et mechanical heart valves during the leakage phase. Ann.leakage ?ow in the hinge of a St. Jude medical((r)) regent mechanical heart valve.leakage ?ow of regurgitation jets, 22,28 ori?ces, 23 and at the hinges 36 of mechanical valves.

  9. Noise, sign problems, and statistics

    E-Print Network [OSTI]

    Michael G. Endres; David B. Kaplan; Jong-Wan Lee; Amy N. Nicholson

    2011-06-01

    We show how sign problems in simulations of many-body systems can manifest themselves in the form of heavy-tailed correlator distributions, similar to what is seen in electron propagation through disordered media. We propose an alternative statistical approach for extracting ground state energies in such systems, illustrating the method with a toy model and with lattice data for unitary fermions.

  10. Problems in unification and supergravity

    SciTech Connect (OSTI)

    Farrar, G.; Henyey, F. (eds.)

    1984-01-01

    Problems in unification of the various gauge groups, quantum gravity, supersymmetry and supergravity, compact dimensions of space-time, and conditions at the beginning of the universe are discussed. Separate entries were prepared for the data base for the 15 papers presented. (WHK)

  11. MATRIXDEPENDENT MULTIGRIDHOMOGENIZATION FOR DIFFUSION PROBLEMS

    E-Print Network [OSTI]

    ≠dependent prolongations and the construction of coarse grid operators by means of the Galerkin approximation. In numerical on a micro≠scale level, require that all length scales appearing in the problem are completely resolved. In numerical simulation however, due to reasons of storage requirements and numerical complexity

  12. Resurgent functions and splitting problems

    E-Print Network [OSTI]

    Sauzin, David

    2006-01-01

    The present text is an introduction to \\'Ecalle's theory of resurgent functions and alien calculus, in connection with problems of exponentially small separatrix splitting. An outline of the resurgent treatment of Abel's equation for resonant dynamics in one complex variable is included. The emphasis is on examples of nonlinear difference equations, as a simple and natural way of introducing the concepts.

  13. Some Ramsey Problems Involving Triangles -

    E-Print Network [OSTI]

    Radziszowski, Stanislaw P.

    Some Ramsey Problems Involving Triangles - Computational Approach Stanislaw Pawel Radziszowski Department of Computer Science Rochester Institute of Technology, NY ramsey@dimacs, 28 may 2009 1/40 #12;Outline - Triangles Everywhere or avoiding K3 in some/most colors 1 Ramsey Numbers - Two Colors Some known

  14. Software Quality Assurance Problem frames

    E-Print Network [OSTI]

    Wallace, Charles

    report-world a c a b a: RW!{WorldInfo} b: IR!{Queries}, IS!{Reports} c: IR!{DisplayState} "When world sends report... causing appropriate change in display state." #12;Information problem real world: may world interpreted by sensor or "data-entry" person real world a: S!{SensorData} b: RW!{WorldData} b

  15. Substation automation problems and possibilities

    SciTech Connect (OSTI)

    Smith, H.L.

    1996-10-01

    The evolutionary growth in the use and application of microprocessors in substations has brought the industry to the point of considering integrated substation protection, control, and monitoring systems. An integrated system holds the promise of greatly reducing the design, documentation, and implementation cost for the substation control, protection, and monitoring systems. This article examines the technical development path and the present implementation problems.

  16. Modeling Photon Generation Problem Presenter

    E-Print Network [OSTI]

    Edwards, David A.

    on Mathematical Problems in Industry June 13≠17, 2011 New Jersey Institute of Technology #12;Section 1 generation in quantum experiments, involve one or more pump fields at relatively large amplitude interacting linear form of the CMEs in the undepleted-pump regime, where the CMEs can formally be solved to yield

  17. Grasers: proposals, problems, and prospects

    SciTech Connect (OSTI)

    Baldwin, G.C.

    1982-01-01

    The possibility and potentiality of amplification of recoilless radiation emitted by nuclear isomers has long been recognized; nevertheless, development of gamma-ray lasers continues to await resolution of the pumping vs. linebreadth dilemma. Problems that accompany proposals for reducing the excitation requirements and suggest areas of investigation that may contribute to resolving the dilemma are identified; several involve use of optical lasers.

  18. Seismic Vessel Problem Gregory Gutin

    E-Print Network [OSTI]

    Gutin, Gregory

    Seismic Vessel Problem Gregory Gutin , Helmut Jakubowicz , Shuki Ronen and Alexei Zverovitchß November 14, 2003 Abstract We introduce and study a new combinatorial optimization prob- lem, the Seismic computational experience with solving SVP instances drawn from industrial practice (geophysical seismic acquisi

  19. Structural Mechanics & Solid Mechanics A finite element toolbox to MATLAB

    E-Print Network [OSTI]

    Ehrhardt, Matthias

    Structural Mechanics & Solid Mechanics Department of Mechanics and Materials CALFEM A finite.3 Copyright © 1999 by Structural Mechanics, LTH, Sweden. Printed by JABE Offset, Lund, Sweden. ISRN LUTVDG/TVSM--99/9001--SE (1-265) ISSN 0281-6679 Department of Mechanics and Materials Structural Mechanics #12;The

  20. Solar mechanics thermal response capabilities.

    SciTech Connect (OSTI)

    Dobranich, Dean D.

    2009-07-01

    In many applications, the thermal response of structures exposed to solar heat loads is of interest. Solar mechanics governing equations were developed and integrated with the Calore thermal response code via user subroutines to provide this computational simulation capability. Solar heat loads are estimated based on the latitude and day of the year. Vector algebra is used to determine the solar loading on each face of a finite element model based on its orientation relative to the sun as the earth rotates. Atmospheric attenuation is accounted for as the optical path length varies from sunrise to sunset. Both direct and diffuse components of solar flux are calculated. In addition, shadowing of structures by other structures can be accounted for. User subroutines were also developed to provide convective and radiative boundary conditions for the diurnal variations in air temperature and effective sky temperature. These temperature boundary conditions are based on available local weather data and depend on latitude and day of the year, consistent with the solar mechanics formulation. These user subroutines, coupled with the Calore three-dimensional thermal response code, provide a complete package for addressing complex thermal problems involving solar heating. The governing equations are documented in sufficient detail to facilitate implementation into other heat transfer codes. Suggestions for improvements to the approach are offered.