National Library of Energy BETA

Sample records for maximum luminous efficacy

  1. Luminous Efficacy Standards for General Purpose Lights

    Broader source: Energy.gov [DOE]

    *Efficacy refers to the overall energy efficiency of light and is measured in lumens (measure of light output) per watt (measure of power input). The efficacy of a typical incandescent light bulb...

  2. Luminant Energy | Open Energy Information

    Open Energy Info (EERE)

    Texas Phone Number: 214.812.4600 Website: www.luminant.com Twitter: @LuminantPower Facebook: https:www.facebook.comLuminantPower Outage Hotline: 214.812.4600 References: EIA...

  3. Luminant restores pre-owned draglines

    SciTech Connect (OSTI)

    Donovan, A.

    2009-11-15

    Luminant, a Texas-based coal producer, brings two draglines back to life by moving and refurbishing them. 10 photos.

  4. Orbital masses of nearby luminous galaxies

    SciTech Connect (OSTI)

    Karachentsev, Igor D.; Kudrya, Yuri N. E-mail: yukudrya@gmail.com

    2014-09-01

    We use observational properties of galaxies accumulated in the Updated Nearby Galaxy Catalog to derive a dark matter mass of luminous galaxies via motions of their companions. The data on orbital-to-stellar mass ratio are presented for 15 luminous galaxies situated within 11 Mpc from us: the Milky Way, M31, M81, NGC 5128, IC342, NGC 253, NGC 4736, NGC 5236, NGC 6946, M101, NGC 4258, NGC 4594, NGC 3115, NGC 3627, and NGC 3368, as well as for a composite suite around other nearby galaxies of moderate and low luminosity. The typical ratio for these galaxies is M {sub orb}/M {sub *} = 31, corresponding to the mean local density of matter ? {sub m} = 0.09, i.e., one-third of the global cosmic density. This quantity seems to be rather an upper limit of dark matter density, since the peripheric population of the suites may suffer from the presence of fictitious unbound members. We note that the Milky Way and M31 halos have lower dimensions and lower stellar masses than those of the other 13 nearby luminous galaxies. However, the dark-to-stellar mass ratio for both the Milky Way and M31 is typical for other neighboring luminous galaxies. The distortion in the Hubble flow, observed around the Local Group and five other neighboring groups, yields their total masses within the radius of a zero velocity surface, R {sub 0}; these masses are slightly lower than the orbital and virial values. This difference may be due to the effect of dark energy producing a kind of 'mass defect' within R {sub 0}.

  5. Rapidly evolving and luminous transients from Pan-STARRS1

    SciTech Connect (OSTI)

    Drout, M. R.; Chornock, R.; Soderberg, A. M.; Sanders, N. E.; McKinnon, R.; Milisavljevic, D.; Margutti, R.; Berger, E.; Calkins, M.; Fong, W.; Kirshner, R. P.; Lunnan, R. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Rest, A. [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Foley, R. J. [Astronomy Department, University of Illinois at Urbana-Champaign, 1002 West Green Street, Urbana, IL 61801 (United States); Gezari, S. [Department of Astronomy, University of Maryland, College Park, MD 20742-2421 (United States); Huber, M. E. [Institute for Astronomy, University of Hawaii at Manoa, Honolulu, HI 96822 (United States); Kankare, E.; Mattila, S. [Finnish Centre for Astronomy with ESO (FINCA), University of Turku, Vislntie 20, FI-21500 Piikki (Finland); Leibler, C. [Department of Astronomy and Astrophysics, University of California, Santa Cruz, CA 95060 (United States); Marion, G. H., E-mail: mdrout@cfa.harvard.edu [Department of Astronomy, University of Texas at Austin, Austin, TX 78712 (United States); and others

    2014-10-10

    In the past decade, several rapidly evolving transients have been discovered whose timescales and luminosities are not easily explained by traditional supernovae (SNe) models. The sample size of these objects has remained small due, at least in part, to the challenges of detecting short timescale transients with traditional survey cadences. Here we present the results from a search within the Pan-STARRS1 Medium Deep Survey (PS1-MDS) for rapidly evolving and luminous transients. We identify 10 new transients with a time above half-maximum (t {sub 1/2}) of less than 12 days and 16.5 > M > 20 mag. This increases the number of known events in this region of SN phase space by roughly a factor of three. The median redshift of the PS1-MDS sample is z = 0.275 and they all exploded in star-forming galaxies. In general, the transients possess faster rise than decline timescale and blue colors at maximum light (g {sub P1} r {sub P1} ? 0.2). Best-fit blackbodies reveal photospheric temperatures/radii that expand/cool with time and explosion spectra taken near maximum light are dominated by a blue continuum, consistent with a hot, optically thick, ejecta. We find it difficult to reconcile the short timescale, high peak luminosity (L > 10{sup 43} erg s{sup 1}), and lack of UV line blanketing observed in many of these transients with an explosion powered mainly by the radioactive decay of {sup 56}Ni. Rather, we find that many are consistent with either (1) cooling envelope emission from the explosion of a star with a low-mass extended envelope that ejected very little (<0.03 M {sub ?}) radioactive material, or (2) a shock breakout within a dense, optically thick, wind surrounding the progenitor star. After calculating the detection efficiency for objects with rapid timescales in the PS1-MDS we find a volumetric rate of 4800-8000 events yr{sup 1} Gpc{sup 3} (4%-7% of the core-collapse SN rate at z = 0.2).

  6. Maximum-likelihood

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Jurisdiction waters of the Gulf of Mexico. Alaska is all onshore. Total crews includes crews with unknown survey dimension. Data are reported on the first and fifteenth of each month, except January when they are reported only on the fifteenth. When semi-monthly values differ for the month, the larger of the two values is shown here. Consequently, this table reflects the maximum number of crews at work at any time during the month. See Definitions, Sources, and Notes link above for more

  7. STAR FORMATION IN TWO LUMINOUS SPIRAL GALAXIES

    SciTech Connect (OSTI)

    Hunter, Deidre A.; Ashburn, Allison; Wright, Teresa; Elmegreen, Bruce G.; Rubin, Vera C.; Jzsa, Gyula I. G.; Struve, Christian

    2013-10-01

    We examined star formation in two very luminous (M{sub V} = 22 to 23) Sc-type spiral galaxies, NGC 801 and UGC 2885, using ultra-deep H? images. We combine these H? images with UBV and Two-Micron All-Sky Survey JHK images and H I maps to explore the star formation characteristics of disk galaxies at high luminosity. H? traces star formation in these galaxies to 4-6 disk scale lengths, but the lack of detection of H? further out is likely due to the loss of Lyman continuum photons. Considering gravitational instabilities alone, we find that the gas and stars in the outer regions are marginally stable in an average sense, but considering dissipative gas and radial and azimuthal forcing, the outer regions are marginally unstable to forming spiral arms. Star formation is taking place in spiral arms, which are regions of locally higher gas densities. Furthermore, we have traced smooth exponential stellar disks over four magnitudes in V-band surface brightness and 4-6 disk scale lengths, in spite of a highly variable gravitational instability parameter. Thus, gravitational instability thresholds do not seem relevant to the stellar disk. One possibility for creating an exponential disk is that the molecular cloud densities and star formation rates have exponential profiles and this fact forces the stellar disk to build up such a profile. Another possibility is that the stellar disk is continuously adjusted to an exponential shape regardless of the star formation profile, for example, through global dynamical processes that scatter stars. However, such scattering processes are only known to operate in spiral systems, in which case they cannot explain the same dilemma of smooth exponential disks observed in dwarf irregular galaxies.

  8. WARM MOLECULAR GAS IN LUMINOUS INFRARED GALAXIES

    SciTech Connect (OSTI)

    Lu, N.; Zhao, Y.; Xu, C. K.; Mazzarella, J. M.; Howell, J.; Appleton, P.; Lord, S.; Schulz, B.; Gao, Y.; Armus, L.; Daz-Santos, T.; Surace, J.; Isaak, K. G.; Petric, A. O.; Charmandaris, V.; Evans, A. S.; Inami, H.; Iwasawa, K.; Leech, J.; Sanders, D. B.; and others

    2014-06-01

    We present our initial results on the CO rotational spectral line energy distribution (SLED) of the J to J1 transitions from J = 4 up to 13 from Herschel SPIRE spectroscopic observations of 65 luminous infrared galaxies (LIRGs) in the Great Observatories All-Sky LIRG Survey. The observed SLEDs change on average from one peaking at J ? 4 to a broad distribution peaking around J ? 6 to 7 as the IRAS 60-to-100?m color, C(60/100), increases. However, the ratios of a CO line luminosity to the total infrared luminosity, L {sub IR}, show the smallest variation for J around 6 or 7. This suggests that, for most LIRGs, ongoing star formation (SF) is also responsible for a warm gas component that emits CO lines primarily in the mid-J regime (5 ? J ? 10). As a result, the logarithmic ratios of the CO line luminosity summed over CO(54), (65), (76), (87) and (109) transitions to L {sub IR}, log R {sub midCO}, remain largely independent of C(60/100), and show a mean value of 4.13 (?log?R{sub midCO}{sup SF}) and a sample standard deviation of only 0.10 for the SF-dominated galaxies. Including additional galaxies from the literature, we show, albeit with a small number of cases, the possibility that galaxies, which bear powerful interstellar shocks unrelated to the current SF, and galaxies, in which an energetic active galactic nucleus contributes significantly to the bolometric luminosity, have their R {sub midCO} higher and lower than R{sub midCO}{sup SF}, respectively.

  9. A plausible (overlooked) super-luminous supernova in the Sloan digital sky survey stripe 82 data

    SciTech Connect (OSTI)

    Kostrzewa-Rutkowska, Zuzanna; Koz?owski, Szymon; Wyrzykowski, ?ukasz; Djorgovski, S. George; Mahabal, Ashish A.; Glikman, Eilat; Koposov, Sergey E-mail: simkoz@astrouw.edu.pl

    2013-12-01

    We present the discovery of a plausible super-luminous supernova (SLSN), found in the archival data of Sloan Digital Sky Survey (SDSS) Stripe 82, called PSN 000123+000504. The supernova (SN) peaked at m {sub g} < 19.4 mag in the second half of 2005 September, but was missed by the real-time SN hunt. The observed part of the light curve (17 epochs) showed that the rise to the maximum took over 30 days, while the decline time lasted at least 70 days (observed frame), closely resembling other SLSNe of SN 2007bi type. The spectrum of the host galaxy reveals a redshift of z = 0.281 and the distance modulus of ? = 40.77 mag. Combining this information with the SDSS photometry, we found the host galaxy to be an LMC-like irregular dwarf galaxy with an absolute magnitude of M{sub B} = 18.2 0.2 mag and an oxygen abundance of 12+log?[O/H]=8.30.2; hence, the SN peaked at M {sub g} < 21.3 mag. Our SLSN follows the relation for the most energetic/super-luminous SNe exploding in low-metallicity environments, but we found no clear evidence for SLSNe to explode in low-luminosity (dwarf) galaxies only. The available information on the PSN 000123+000504 light curve suggests the magnetar-powered model as a likely scenario of this event. This SLSN is a new addition to a quickly growing family of super-luminous SNe.

  10. Removal to Maximum Extent Practical

    Broader source: Energy.gov [DOE]

    Summary Notes from 1 November 2007 Generic Technical Issue Discussion on Removal of Highly Radioactive Radionuclides/Key Radionuclides to the Maximum Extent Practical

  11. SUBARU AND GEMINI HIGH SPATIAL RESOLUTION INFRARED 18 {mu}m IMAGING OBSERVATIONS OF NEARBY LUMINOUS INFRARED GALAXIES

    SciTech Connect (OSTI)

    Imanishi, Masatoshi; Imase, Keisuke; Oi, Nagisa; Ichikawa, Kohei

    2011-05-15

    We present the results of a ground-based, high spatial resolution infrared 18 {mu}m imaging study of nearby luminous infrared galaxies (LIRGs), using the Subaru 8.2 m and Gemini-South 8.1 m telescopes. The diffraction-limited images routinely achieved with these telescopes in the Q band (17-23 {mu}m) allow us to investigate the detailed spatial distribution of infrared emission in these LIRGs. We then investigate whether the emission surface brightnesses are modest, as observed in starbursts, or are so high that luminous active galactic nuclei (AGNs; high emission surface brightness energy sources) are indicated. The sample consists of 18 luminous buried AGN candidates and starburst-classified LIRGs identified in earlier infrared spectroscopy. We find that the infrared 18 {mu}m emission from the buried AGN candidates is generally compact, and the estimated emission surface brightnesses are high, sometimes exceeding the maximum value observed in and theoretically predicted for a starburst phenomenon. The starburst-classified LIRGs usually display spatially extended 18 {mu}m emission and the estimated emission surface brightnesses are modest, within the range sustained by a starburst phenomenon. The general agreement between infrared spectroscopic and imaging energy diagnostic methods suggests that both are useful tools for understanding the hidden energy sources of the dusty LIRG population.

  12. Machine learning helps discover the most luminous supernova in history

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Machine learning helps discover supernova Machine learning helps discover the most luminous supernova in history Machine-learning technology developed at Los Alamos National Laboratory played a key role in the discovery of supernova ASASSN-15lh. January 14, 2016 An artist's impression of the record-breaking superluminous supernova ASASSN-15lh as it would appear from an exoplanet located about 10,000 light years away in the host galaxy of the supernova. (Credit: Beijing Planetarium / Jin Ma) An

  13. Directional sky luminance versus cloud cover and solar position

    SciTech Connect (OSTI)

    Harrison, A.W. )

    1991-01-01

    Measurements of sky luminance at 121 equally spaced points ({theta},{phi}) over the sky dome under clear, partly cloudy and overcast skies have led to the following analytical expression for normalized sky luminance L{sub v}({theta},{phi},{theta}*,C) = CL {sub vc}{sup 0}({theta},{phi},{theta}*) + (1 {minus} C)L{sub vc}{sup c}({theta},{phi},{theta}*) L{sub vc}{sup 0}({theta},{phi},{theta}I) = 0.40 + 0.21{theta}* + 0.27 cos {theta} + 1.45 e{sup {minus}2.4l{psi}}L{sub vc}({theta},{phi},{theta}*) = (1.28 + 147e{sup {minus}11.1{phi}} + 4.28 cos{sup 2}{phi} cos{theta}*)*(1 {minus} e{sup {minus}0.42sec{theta}})*(1{minus}e{sup {minus}0.67sec{theta}}) where {theta} = sky point zenith angle, {phi} = sky point azimuth angle, {theta}* = solar zenith angle, {phi} = scattering angle between sky, and sun direction and C = opaque cloud cover ({theta}* and {phi} in radians).

  14. DOE - Office of Legacy Management -- Shannon Luminous Metals Co - CA 0-03

    Office of Legacy Management (LM)

    Shannon Luminous Metals Co - CA 0-03 FUSRAP Considered Sites Site: SHANNON LUMINOUS METALS CO. (CA.0-03 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: Shannon Luminous Metals CA.0-03-3 Location: 7356 Santa Monica Blvd. , Hollywood , California CA.0-03-1 Evaluation Year: 1987 CA.0-03-2 Site Operations: Research and development of uranium use in luminous paint pigments in the 1950s. CA.0-03-1 Site Disposition: Eliminated - No Authority - NRC licensed

  15. OBSCURATION BY GAS AND DUST IN LUMINOUS QUASARS

    SciTech Connect (OSTI)

    Usman, S. M.; Murray, S. S.; Hickox, R. C.; Brodwin, M.

    2014-06-10

    We explore the connection between absorption by neutral gas and extinction by dust in mid-infrared (IR) selected luminous quasars. We use a sample of 33 quasars at redshifts 0.7 < z ? 3 in the 9deg{sup 2} Botes multiwavelength survey field that are selected using Spitzer Space Telescope Infrared Array Camera colors and are well-detected as luminous X-ray sources (with >150 counts) in Chandra observations. We divide the quasars into dust-obscured and unobscured samples based on their optical to mid-IR color, and measure the neutral hydrogen column density N {sub H} through fitting of the X-ray spectra. We find that all subsets of quasars have consistent power law photon indices ? ? 1.9 that are uncorrelated with N {sub H}. We classify the quasars as gas-absorbed or gas-unabsorbed if N {sub H} > 10{sup 22} cm{sup 2} or N {sub H} < 10{sup 22} cm{sup 2}, respectively. Of 24 dust-unobscured quasars in the sample, only one shows clear evidence for significant intrinsic N {sub H}, while 22 have column densities consistent with N {sub H} < 10{sup 22} cm{sup 2}. In contrast, of the nine dust-obscured quasars, six show evidence for intrinsic gas absorption, and three are consistent with N {sub H} < 10{sup 22} cm{sup 2}. We conclude that dust extinction in IR-selected quasars is strongly correlated with significant gas absorption as determined through X-ray spectral fitting. These results suggest that obscuring gas and dust in quasars are generally co-spatial, and confirm the reliability of simple mid-IR and optical photometric techniques for separating quasars based on obscuration.

  16. Boiler Maximum Achievable Control Technology (MACT) Technical...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Boiler Maximum Achievable Control Technology (MACT) Technical Assistance - Fact Sheet, April 2015 Boiler Maximum Achievable Control Technology (MACT) Technical Assistance - Fact ...

  17. Maximum Performance Group MPG | Open Energy Information

    Open Energy Info (EERE)

    Maximum Performance Group MPG Jump to: navigation, search Name: Maximum Performance Group (MPG) Place: College Point, New York Zip: 11356 Product: Technology based energy and asset...

  18. Mirant Potomac, Alexandria, Virginia: Maximum Impacts Predicted...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    PRIME Mirant Potomac, Alexandria, Virginia: Maximum Impacts Predicted by AERMOD-PRIME Docket No. EO-05-01: Mirant Potomac, Alexandria, Virginia: Maximum Impacts Predicted by ...

  19. Cosmological information in the intrinsic alignments of luminous red galaxies

    SciTech Connect (OSTI)

    Chisari, Nora Elisa; Dvorkin, Cora E-mail: cdvorkin@ias.edu

    2013-12-01

    The intrinsic alignments of galaxies are usually regarded as a contaminant to weak gravitational lensing observables. The alignment of Luminous Red Galaxies, detected unambiguously in observations from the Sloan Digital Sky Survey, can be reproduced by the linear tidal alignment model of Catelan, Kamionkowski and Blandford (2001) on large scales. In this work, we explore the cosmological information encoded in the intrinsic alignments of red galaxies. We make forecasts for the ability of current and future spectroscopic surveys to constrain local primordial non-Gaussianity and Baryon Acoustic Oscillations (BAO) in the cross-correlation function of intrinsic alignments and the galaxy density field. For the Baryon Oscillation Spectroscopic Survey, we find that the BAO signal in the intrinsic alignments is marginally significant with a signal-to-noise ratio of 1.8 and 2.2 with the current LOWZ and CMASS samples of galaxies, respectively, and increasing to 2.3 and 2.7 once the survey is completed. For the Dark Energy Spectroscopic Instrument and for a spectroscopic survey following the EUCLID redshift selection function, we find signal-to-noise ratios of 12 and 15, respectively. Local type primordial non-Gaussianity, parametrized by f{sub NL} = 10, is only marginally significant in the intrinsic alignments signal with signal-to-noise ratios < 2 for the three surveys considered.

  20. Luminous and variable stars in M31 and M33. II. Luminous blue variables, candidate LBVs, Fe II emission line stars, and other supergiants

    SciTech Connect (OSTI)

    Humphreys, Roberta M.; Davidson, Kris; Weis, Kerstin; Bomans, D. J.; Burggraf, Birgitta E-mail: kweis@astro.rub.de

    2014-07-20

    An increasing number of non-terminal eruptions are being found in the numerous surveys for optical transients. Very little is known about these giant eruptions, their progenitors and their evolutionary state. A greatly improved census of the likely progenitor class, including the most luminous evolved stars, the luminous blue variables (LBVs), and the warm and cool hypergiants is now needed for a complete picture of the final pre-supernova stages of very massive stars. We have begun a survey of the evolved and unstable luminous star populations in several nearby resolved galaxies. In this second paper on M31 and M33, we review the spectral characteristics, spectral energy distributions, circumstellar ejecta, and evidence for mass loss for 82 luminous and variable stars. We show that many of these stars have warm circumstellar dust including several of the Fe II emission line stars, but conclude that the confirmed LBVs in M31 and M33 do not. The confirmed LBVs have relatively low wind speeds even in their hot, quiescent or visual minimum state compared to the B-type supergiants and Of/WN stars which they spectroscopically resemble. The nature of the Fe II emission line stars and their relation to the LBV state remains uncertain, but some have properties in common with the warm hypergiants and the sgB[e] stars. Several individual stars are discussed in detail. We identify three possible candidate LBVs and three additional post-red supergiant candidates. We suggest that M33-013406.63 (UIT301,B416) is not an LBV/S Dor variable, but is a very luminous late O-type supergiant and one of the most luminous stars or pair of stars in M33.

  1. Mirant Potomac, Alexandria, Virginia: Maximum Impacts Predicted...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Mirant Potomac, Alexandria, Virginia: Maximum Impacts Predicted by AERMOD-PRIME, Units 5, 1, 2 SO2 Case Docket No. EO-05-01: Mirant Potomac, Alexandria, Virginia: Maximum Impacts ...

  2. Mirant Potomac, Alexandria, Virginia: Maximum Impacts Predicted...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Mirant Potomac, Alexandria, Virginia: Maximum Impacts Predicted by AERMOD-PRIME, Units 4, 1, 2 SO2 Case Docket No. EO-05-01: Mirant Potomac, Alexandria, Virginia: Maximum Impacts ...

  3. Mirant Potomac, Alexandria, Virginia: Maximum Impacts Predicted...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Mirant Potomac, Alexandria, Virginia: Maximum Impacts Predicted by AERMOD-PRIME, Units 3, 1, 2 SO2 Case Docket No. EO-05-01: Mirant Potomac, Alexandria, Virginia: Maximum Impacts ...

  4. CHARACTERIZATION OF THE MOST LUMINOUS STAR IN M33: A SUPER SYMBIOTIC BINARY

    SciTech Connect (OSTI)

    Miko?ajewska, Joanna; I?kiewicz, Krystian; Caldwell, Nelson; Shara, Michael M.

    2015-01-30

    We present the first spectrum of the most luminous infrared star in M33, and use it to demonstrate that the object is almost certainly a binary composed of a massive O star and a dust-enshrouded red hypergiant. This is the most luminous symbiotic binary ever discovered. Its radial velocity is an excellent match to that of the hydrogen gas in the disk of M33, supporting our interpretation that it is a very young and massive binary star.

  5. Luminous blue variables and superluminous supernovae from binary mergers

    SciTech Connect (OSTI)

    Justham, Stephen; Podsiadlowski, Philipp; Vink, Jorick S. E-mail: podsi@astro.ox.ac.uk

    2014-12-01

    Evidence suggests that the direct progenitor stars of some core-collapse supernovae (CCSNe) are luminous blue variables (LBVs), perhaps including some Type II 'superluminous supernovae' (SLSNe). We examine models in which massive stars gain mass soon after the end of core hydrogen burning. These are mainly intended to represent mergers following a brief contact phase during early Case B mass transfer, but may also represent stars which gain mass in the Hertzsprung Gap or extremely late during the main-sequence phase for other reasons. The post-accretion stars spend their core helium-burning phase as blue supergiants (BSGs), and many examples are consistent with being LBVs at the time of core collapse. Other examples are yellow supergiants at explosion. We also investigate whether such post-accretion stars may explode successfully after core collapse. The final core properties of post-accretion models are broadly similar to those of single stars with the same initial mass as the pre-merger primary star. More surprisingly, when early Case B accretion does affect the final core properties, the effect appears likely to favor a successful SN explosion, i.e., to make the core properties more like those of a lower-mass single star. However, the detailed structures of these cores sometimes display qualitative differences to any single-star model we have calculated. The rate of appropriate binary mergers may match the rate of SNe with immediate LBV progenitors; for moderately optimistic assumptions we estimate that the progenitor birthrate is ?1% of the CCSN rate.

  6. SUBMILLIMETER INTERFEROMETRY OF THE LUMINOUS INFRARED GALAXY NGC 4418: A HIDDEN HOT NUCLEUS WITH AN INFLOW AND AN OUTFLOW

    SciTech Connect (OSTI)

    Sakamoto, Kazushi; Ohyama, Youichi; Aalto, Susanne; Costagliola, Francesco; Martin, Sergio; Wiedner, Martina C.; Wilner, David J.

    2013-02-10

    We have observed the nucleus of the nearby luminous infrared galaxy NGC 4418 with subarcsec resolution at 860 and 450 {mu}m for the first time to characterize its hidden power source. A {approx}20 pc (0.''1) hot dusty core was found inside a 100 pc scale concentration of molecular gas at the galactic center. The 860 {mu}m continuum core has a deconvolved (peak) brightness temperature of 120-210 K. The CO(3-2) peak brightness temperature there is as high as 90 K at 50 pc resolution. The core has a bolometric luminosity of about 10{sup 11} L {sub Sun }, which accounts for most of the galaxy luminosity. It is Compton thick (N {sub H} {approx}> 10{sup 25} cm{sup -2}) and has a high luminosity-to-mass ratio (L/M) {approx} 500 L {sub Sun} M {sub Sun} {sup -1} as well as a high luminosity surface density 10{sup 8.5{+-}0.5} L {sub Sun} pc{sup -2}. These parameters are consistent with an active galactic nucleus to be the main luminosity source (with an Eddington ratio about 0.3), while they can be also due to a young starburst near its maximum L/M. We also found an optical color (reddening) feature that we attribute to an outflow cone emanating from the nucleus. The hidden hot nucleus thus shows evidence of both an inflow, previously seen with absorption lines, and the new outflow reported here in a different direction. The nucleus must be rapidly evolving with these gas flows.

  7. HIGH-DENSITY CIRCUMSTELLAR INTERACTION IN THE LUMINOUS TYPE IIn SN 2010jl: THE FIRST 1100 DAYS

    SciTech Connect (OSTI)

    Fransson, Claes; Ergon, Mattias; Sollerman, Jesper [Oskar Klein Centre, Department of Astronomy, Stockholm University, AlbaNova, SE-106 91 Stockholm (Sweden); Challis, Peter J.; Kirshner, Robert P.; Marion, G. H.; Milisavljevic, Dan; Friedman, Andrew S.; Chornock, Ryan; Czekala, Ian; Soderberg, Alicia [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Chevalier, Roger A. [Department of Astronomy, University of Virginia, P.O. Box 400325, Charlottesville, VA 22904 (United States); France, Kevin [CASA, University of Colorado, 593UCB Boulder, CO 80309-0593 (United States); Smith, Nathan [Steward Observatory, University of Arizona, 933 North Cherry Avenue, Tucson, AZ 85721 (United States); Bufano, Filomena [Departamento de Ciencias Fisicas, Universidad Andres Bello, Avda. Republica 252, Santiago (Chile); Kangas, Tuomas [Tuorla Observatory, University of Turku, Vislntie 20 FI-21500 Piikki (Finland); Larsson, Josefin [KTH, Department of Physics, and the Oskar Klein Centre, AlbaNova, SE-106 91 Stockholm (Sweden); Mattila, Seppo [Finnish Centre for Astronomy with ESO (FINCA), University of Turku, Vislntie 20 FI-21500 Piikki (Finland); Benetti, Stefano [INAF-Osservatorio Astronomico di Padova, Vicolo dellOsservatorio 5, I-35122 Padova (Italy)

    2014-12-20

    Hubble Space Telescope and ground-based observations of the Type IIn supernova (SN) 2010jl are analyzed, including photometry and spectroscopy in the ultraviolet, optical, and near-IR bands, 26-1128 days after first detection. At maximum, the bolometric luminosity was ?3 10{sup 43} erg s{sup 1} and even at 850days exceeds 10{sup 42} erg s{sup 1}. A near-IR excess, dominating after 400days, probably originates in dust in the circumstellar medium (CSM). The total radiated energy is ? 6.5 10{sup 50} erg, excluding the dust component. The spectral lines can be separated into one broad component that is due to electron scattering and one narrow with expansion velocity ?100 km s{sup 1} from the CSM. The broad component is initially symmetric around zero velocity but becomes blueshifted after ?50 days, while remaining symmetric about a shifted centroid velocity. Dust absorption in the ejecta is unlikely to explain the line shifts, and we attribute the shift instead to acceleration by the SN radiation. From the optical lines and the X-ray and dust properties, there is strong evidence for large-scale asymmetries in the CSM. The ultraviolet lines indicate CNO processing in the progenitor, while the optical shows a number of narrow coronal lines excited by the X-rays. The bolometric light curve is consistent with a radiative shock in an r {sup 2} CSM with a mass-loss rate of M-dot ?0.1M{sub ?} yr{sup ?1}. The total mass lost is ? 3 M {sub ?}. These properties are consistent with the SN expanding into a CSM characteristic of a luminous blue variable progenitor with a bipolar geometry. The apparent absence of nuclear processing is attributed to a CSM that is still opaque to electron scattering.

  8. Electron energy spectrum and maximum disruption angle under multi...

    Office of Scientific and Technical Information (OSTI)

    Conference: Electron energy spectrum and maximum disruption angle under multi-photon beamstrahlung Citation Details In-Document Search Title: Electron energy spectrum and maximum ...

  9. Electron energy spectrum and maximum disruption angle under multi...

    Office of Scientific and Technical Information (OSTI)

    Electron energy spectrum and maximum disruption angle under multi-photon beamstrahlung Citation Details In-Document Search Title: Electron energy spectrum and maximum disruption ...

  10. Oxidation State Optimization for Maximum Efficiency of NOx Adsorber...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    State Optimization for Maximum Efficiency of NOx Adsorber Catalysts Oxidation State Optimization for Maximum Efficiency of NOx Adsorber Catalysts Presentation given at the 16th ...

  11. C IV and C III] reverberation mapping of the luminous quasar PG 1247+267

    SciTech Connect (OSTI)

    Trevese, D.; Saturni, F. G. [Dipartimento di Fisica, Universit di Roma La Sapienza, Piazzale Aldo Moro, 5, I-00185 Roma (Italy); Perna, M. [Dipartimento di Fisica e Astronomia, Universit di Bologna, Viale Berti Pichat 6/2, I-40127 Bologna (Italy); Vagnetti, F. [Dipartimento di Fisica, Universit di Roma Tor Vergata, Via della Ricerca Scientifica 1, I-00133 Roma (Italy); Dadina, M. [INAF-IASF Bologna, Via Gobetti 101, I-40129 Bologna (Italy)

    2014-11-10

    So far the masses of about 50 active galactic nuclei (AGNs) have been measured through the reverberation mapping technique (RM). Most measurements have been performed for objects of moderate luminosity and redshift, based on H?, which is also used to calibrate the scaling relation that allows single-epoch (SE) mass determination based on AGN luminosity and the width of different emission lines. Due to the complex structure and gas dynamics of the relevant emission region, the SE masses obtained from the C IV(1549 ) line show a large spread around the mean values. Direct RM measures of C IV exist for only six AGNs of low luminosity and redshift, and only one luminous quasar. Since 2003, we have collected photometric and spectroscopic observations of PG1247+267, the most luminous quasar ever analyzed for RM. We provide light curves for the continuum and for C IV(1549 ) and C III](1909 ), and measures of the reverberation time lags based on the SPEAR method. The sizes of the line emission regions assume a ratio of R {sub C} {sub III]}/R {sub C} {sub IV} ? 2, similar to the case of Seyfert galaxies, indicating for the first time a similar ionization stratification in a luminous quasar and low-luminosity nuclei. Due to the relatively small size of the broad line region and the relatively narrow line widths, we estimate a small mass and an anomalously high Eddington ratio. We discuss the possibility that either the shape of the emission region or an amplification of the luminosity caused by gravitational lensing may be partly responsible for the result.

  12. IDENTIFYING LUMINOUS ACTIVE GALACTIC NUCLEI IN DEEP SURVEYS: REVISED IRAC SELECTION CRITERIA

    SciTech Connect (OSTI)

    Donley, J. L.; Koekemoer, A. M.; Brusa, M.; Salvato, M.; Capak, P.; Cardamone, C. N.; Civano, F.; Ilbert, O.; Impey, C. D.; Kartaltepe, J. S.; Miyaji, T.; Sanders, D. B.; Trump, J. R.

    2012-04-01

    Spitzer/IRAC selection is a powerful tool for identifying luminous active galactic nuclei (AGNs). For deep IRAC data, however, the AGN selection wedges currently in use are heavily contaminated by star-forming galaxies, especially at high redshift. Using the large samples of luminous AGNs and high-redshift star-forming galaxies in COSMOS, we redefine the AGN selection criteria for use in deep IRAC surveys. The new IRAC criteria are designed to be both highly complete and reliable, and incorporate the best aspects of the current AGN selection wedges and of infrared power-law selection while excluding high-redshift star-forming galaxies selected via the BzK, distant red galaxy, Lyman-break galaxy, and submillimeter galaxy criteria. At QSO luminosities of log L{sub 2-10keV}(erg s{sup -1}) {>=}44, the new IRAC criteria recover 75% of the hard X-ray and IRAC-detected XMM-COSMOS sample, yet only 38% of the IRAC AGN candidates have X-ray counterparts, a fraction that rises to 52% in regions with Chandra exposures of 50-160 ks. X-ray stacking of the individually X-ray non-detected AGN candidates leads to a hard X-ray signal indicative of heavily obscured to mildly Compton-thick obscuration (log N{sub H} (cm{sup -2}) = 23.5 {+-} 0.4). While IRAC selection recovers a substantial fraction of luminous unobscured and obscured AGNs, it is incomplete to low-luminosity and host-dominated AGNs.

  13. Higher Dimensional Spacetimes for Visualizing and Modeling Subluminal, Luminal and Superluminal Flight

    SciTech Connect (OSTI)

    Froning, H. David; Meholic, Gregory V.

    2010-01-28

    This paper briefly explores higher dimensional spacetimes that extend Meholic's visualizable, fluidic views of: subluminal-luminal-superluminal flight; gravity, inertia, light quanta, and electromagnetism from 2-D to 3-D representations. Although 3-D representations have the potential to better model features of Meholic's most fundamental entities (Transluminal Energy Quantum) and of the zero-point quantum vacuum that pervades all space, the more complex 3-D representations loose some of the clarity of Meholic's 2-D representations of subluminal and superlumimal realms. So, much new work would be needed to replace Meholic's 2-D views of reality with 3-D ones.

  14. TRENDS IN ESTIMATED MIXING DEPTH DAILY MAXIMUMS

    SciTech Connect (OSTI)

    Buckley, R; Amy DuPont, A; Robert Kurzeja, R; Matt Parker, M

    2007-11-12

    Mixing depth is an important quantity in the determination of air pollution concentrations. Fireweather forecasts depend strongly on estimates of the mixing depth as a means of determining the altitude and dilution (ventilation rates) of smoke plumes. The Savannah River United States Forest Service (USFS) routinely conducts prescribed fires at the Savannah River Site (SRS), a heavily wooded Department of Energy (DOE) facility located in southwest South Carolina. For many years, the Savannah River National Laboratory (SRNL) has provided forecasts of weather conditions in support of the fire program, including an estimated mixing depth using potential temperature and turbulence change with height at a given location. This paper examines trends in the average estimated mixing depth daily maximum at the SRS over an extended period of time (4.75 years) derived from numerical atmospheric simulations using two versions of the Regional Atmospheric Modeling System (RAMS). This allows for differences to be seen between the model versions, as well as trends on a multi-year time frame. In addition, comparisons of predicted mixing depth for individual days in which special balloon soundings were released are also discussed.

  15. Theoretical Estimate of Maximum Possible Nuclear Explosion

    DOE R&D Accomplishments [OSTI]

    Bethe, H. A.

    1950-01-31

    The maximum nuclear accident which could occur in a Na-cooled, Be moderated, Pu and power producing reactor is estimated theoretically. (T.R.H.) 2O82 Results of nuclear calculations for a variety of compositions of fast, heterogeneous, sodium-cooled, U-235-fueled, plutonium- and power-producing reactors are reported. Core compositions typical of plate-, pin-, or wire-type fuel elements and with uranium as metal, alloy, and oxide were considered. These compositions included atom ratios in the following range: U-23B to U-235 from 2 to 8; sodium to U-235 from 1.5 to 12; iron to U-235 from 5 to 18; and vanadium to U-235 from 11 to 33. Calculations were performed to determine the effect of lead and iron reflectors between the core and blanket. Both natural and depleted uranium were evaluated as the blanket fertile material. Reactors were compared on a basis of conversion ratio, specific power, and the product of both. The calculated results are in general agreement with the experimental results from fast reactor assemblies. An analysis of the effect of new cross-section values as they became available is included. (auth)

  16. Table lamp with dynamically controlled lighting distribution and uniformly illuminated luminous shade

    DOE Patents [OSTI]

    Siminovitch, Michael J.; Page, Erik R.

    2002-01-01

    A double lamp table or floor lamp lighting system has a pair of compact fluorescent lamps (CFLs) or other lamps arranged vertically, i.e. one lamp above the other, with a reflective septum in between. By selectively turning on one or both of the CFLs, down lighting, up lighting, or both up and down lighting is produced. The control system can also vary the light intensity from each CFL. The reflective septum ensures that almost all the light produced by each lamp will be directed into the desired light distribution pattern which is selected and easily changed by the user. In a particular configuration, the reflective septum is bowl shaped, with the upper CFL sitting in the bowl, and a luminous shade hanging down from the bowl. The lower CFL provides both task lighting and uniform shade luminance. Planar compact fluorescent lamps, e.g. circular CFLs, particularly oriented horizontally, are preferable. CFLs provide energy efficiency. However, other types of lamps, including incandescent, halogen, and LEDs can also be used in the fixture. The lighting system may be designed for the home, hospitality, office or other environments.

  17. Tumorigenesis in the U.S. radium luminizers: How unsafe was this occupation?

    SciTech Connect (OSTI)

    Thomas, R.G.

    1994-05-01

    Dose-response data are presented from the U.S. female workers who were exposed to radium through the painting of luminous dials and who subsequently had their skeletal burdens measured by whole-body counting and radon breath analyses. Lognormal data analyses were done for radium-induced bone sarcomas and head carcinomas after the populations of the respective doses were first determined to be lognormally distributed. The calculated geometric mean and standard deviation for each dose population were used to construct lognormal distributions that subsequently could be used for intercomparisons. To date, a total of 1,391 female luminizers with average estimated skeletal doses below 10 Gy have not shown bone sarcomas or head carcinomas. A primary purpose of this paper is to support the case that {sup 226.228}Ra is one of the radionuclide sources that exemplify in humans a {open_quote}threshold{close_quotes} dose or a dose below which there should be little concern for tumorigenesis.

  18. MicroRNA-139 suppresses proliferation in luminal type breast cancer cells by targeting Topoisomerase II alpha

    SciTech Connect (OSTI)

    Hua, Wei; Sa, Ke-Di; Zhang, Xiang; Jia, Lin-Tao; Zhao, Jing; Yang, An-Gang; Zhang, Rui; Fan, Jing; Bian, Ka

    2015-08-07

    The classification of molecular subtypes of breast cancer improves the prognostic accuracy and therapeutic benefits in clinic. However, because of the complexity of breast cancer, more biomarkers and functional molecules need to be explored. Here, analyzing the data in a huge cohort of breast cancer patients, we found that Topoisomerase II alpha (TOP2a), an important target of chemotherapy is a biomarker for prognosis in luminal type breast cancer patients, but not in basal like or HER2 positive breast cancer patients. We identified that miR-139, a previous reported anti-metastatic microRNA targets 3’-untranslated region (3′UTR) of TOP2a mRNA. Further more, we revealed that the forced expression of miR-139 reduces the TOP2a expression at both mRNA and protein levels. And our functional experiments showed that the ectopic expression of miR-139 remarkably inhibits proliferation in luminal type breast cancer cells, while exogenous TOP2a expression could rescue inhibition of cell proliferation mediated by miR-139. Collectively, our present study demonstrates the miR-139-TOP2a regulatory axis is important for proliferation in luminal type breast cancer cells. This functional link may help us to further understand the specificity of subtypes of breast cancer and optimize the strategy of cancer treatment. - Highlights: • High levels of TOP2a expression are closely associated with poor prognosis in luminal type breast cancer patients. • TOP2a is a novel target of miR-139. • Overexpression of miR-139 inhibits proliferation in luminal type breast cancer cells. • TOP2a is essential for miR-139-induced growth arrest in luminal type breast cancer cells.

  19. Property:Maximum Velocity(m/s) | Open Energy Information

    Open Energy Info (EERE)

    Velocity(ms) Jump to: navigation, search Property Name Maximum Velocity(ms) Property Type String Pages using the property "Maximum Velocity(ms)" Showing 25 pages using this...

  20. Property:Maximum Wave Length(m) | Open Energy Information

    Open Energy Info (EERE)

    Length(m) Jump to: navigation, search Property Name Maximum Wave Length(m) Property Type String Pages using the property "Maximum Wave Length(m)" Showing 18 pages using this...

  1. Property:Maximum Wave Height(m) | Open Energy Information

    Open Energy Info (EERE)

    Jump to: navigation, search Property Name Maximum Wave Height(m) Property Type String Pages using the property "Maximum Wave Height(m)" Showing 25 pages using this property....

  2. Extra-nuclear starbursts: young luminous Hinge clumps in interacting galaxies

    SciTech Connect (OSTI)

    Smith, Beverly J.; Giroux, Mark L.; Soria, Roberto; Struck, Curtis; Swartz, Douglas A.; Yukita, Mihoko E-mail: girouxm@etsu.edu E-mail: curt@iastate.edu

    2014-03-01

    Hinge clumps are luminous knots of star formation near the base of tidal features in some interacting galaxies. We use archival Hubble Space Telescope (HST) UV/optical/IR images and Chandra X-ray maps along with Galaxy Evolution Explorer UV, Spitzer IR, and ground-based optical/near-IR images to investigate the star forming properties in a sample of 12 hinge clumps in five interacting galaxies. The most extreme of these hinge clumps have star formation rates of 1-9 M {sub ?} yr{sup 1}, comparable to or larger than the 'overlap' region of intense star formation between the two disks of the colliding galaxy system the Antennae. In the HST images, we have found remarkably large and luminous sources at the centers of these hinge clumps. These objects are much larger and more luminous than typical 'super star clusters' in interacting galaxies, and are sometimes embedded in a linear ridge of fainter star clusters, consistent with star formation along a narrow caustic. These central sources have FWHM diameters of ?70 pc, compared to ?3 pc in 'ordinary' super star clusters. Their absolute I magnitudes range from M{sub I} ? 12.2 to 16.5; thus, if they are individual star clusters they would lie near the top of the 'super star cluster' luminosity function of star clusters. These sources may not be individual star clusters, but instead may be tightly packed groups of clusters that are blended together in the HST images. Comparison to population synthesis modeling indicates that the hinge clumps contain a range of stellar ages. This is consistent with expectations based on models of galaxy interactions, which suggest that star formation may be prolonged in these regions. In the Chandra images, we have found strong X-ray emission from several of these hinge clumps. In most cases, this emission is well-resolved with Chandra and has a thermal X-ray spectrum, thus it is likely due to hot gas associated with the star formation. The ratio of the extinction-corrected diffuse X

  3. SUPER-LUMINOUS TYPE Ic SUPERNOVAE: CATCHING A MAGNETAR BY THE TAIL

    SciTech Connect (OSTI)

    Inserra, C.; Smartt, S. J.; Jerkstrand, A.; Fraser, M.; Wright, D.; Smith, K.; Chen, T.-W.; Kotak, R.; Nicholl, M.; Valenti, S.; Pastorello, A.; Benetti, S.; Bresolin, F.; Kudritzki, R. P.; Burgett, W. S.; Chambers, K. C.; Flewelling, H.; Botticella, M. T.; Ergon, M.; Fynbo, J. P. U.; and others

    2013-06-20

    We report extensive observational data for five of the lowest redshift Super-Luminous Type Ic Supernovae (SL-SNe Ic) discovered to date, namely, PTF10hgi, SN2011ke, PTF11rks, SN2011kf, and SN2012il. Photometric imaging of the transients at +50 to +230 days after peak combined with host galaxy subtraction reveals a luminous tail phase for four of these SL-SNe. A high-resolution, optical, and near-infrared spectrum from xshooter provides detection of a broad He I {lambda}10830 emission line in the spectrum (+50 days) of SN2012il, revealing that at least some SL-SNe Ic are not completely helium-free. At first sight, the tail luminosity decline rates that we measure are consistent with the radioactive decay of {sup 56}Co, and would require 1-4 M{sub Sun} of {sup 56}Ni to produce the luminosity. These {sup 56}Ni masses cannot be made consistent with the short diffusion times at peak, and indeed are insufficient to power the peak luminosity. We instead favor energy deposition by newborn magnetars as the power source for these objects. A semi-analytical diffusion model with energy input from the spin-down of a magnetar reproduces the extensive light curve data well. The model predictions of ejecta velocities and temperatures which are required are in reasonable agreement with those determined from our observations. We derive magnetar energies of 0.4 {approx}< E(10{sup 51} erg) {approx}< 6.9 and ejecta masses of 2.3 {approx}< M{sub ej}(M{sub Sun }) {approx}< 8.6. The sample of five SL-SNe Ic presented here, combined with SN 2010gx-the best sampled SL-SNe Ic so far-points toward an explosion driven by a magnetar as a viable explanation for all SL-SNe Ic.

  4. Methane, carbon monoxide, and ammonia in brown dwarfs and self-luminous giant planets

    SciTech Connect (OSTI)

    Zahnle, Kevin J.; Marley, Mark S. E-mail: Mark.S.Marley@NASA.gov

    2014-12-10

    We address disequilibrium abundances of some simple molecules in the atmospheres of solar composition brown dwarfs and self-luminous extrasolar giant planets using a kinetics-based one-dimensional atmospheric chemistry model. Our approach is to use the full kinetics model to survey the parameter space with effective temperatures between 500 K and 1100 K. In all of these worlds, equilibrium chemistry favors CH{sub 4} over CO in the parts of the atmosphere that can be seen from Earth, but in most disequilibrium favors CO. The small surface gravity of a planet strongly discriminates against CH{sub 4} when compared to an otherwise comparable brown dwarf. If vertical mixing is like Jupiter's, the transition from methane to CO occurs at 500 K in a planet. Sluggish vertical mixing can raise this to 600 K, but clouds or more vigorous vertical mixing could lower this to 400 K. The comparable thresholds in brown dwarfs are 1100 100 K. Ammonia is also sensitive to gravity, but, unlike CH{sub 4}/CO, the NH{sub 3}/N{sub 2} ratio is insensitive to mixing, which makes NH{sub 3} a potential proxy for gravity. HCN may become interesting in high-gravity brown dwarfs with very strong vertical mixing. Detailed analysis of the CO-CH{sub 4} reaction network reveals that the bottleneck to CO hydrogenation goes through methanol, in partial agreement with previous work. Simple, easy to use quenching relations are derived by fitting to the complete chemistry of the full ensemble of models. These relations are valid for determining CO, CH{sub 4}, NH{sub 3}, HCN, and CO{sub 2} abundances in the range of self-luminous worlds we have studied, but may not apply if atmospheres are strongly heated at high altitudes by processes not considered here (e.g., wave breaking).

  5. HERSCHEL OBSERVATIONS OF FAR-INFRARED COOLING LINES IN INTERMEDIATE REDSHIFT (ULTRA)-LUMINOUS INFRARED GALAXIES

    SciTech Connect (OSTI)

    Rigopoulou, D.; Magdis, G. E.; Thatte, N.; Hopwood, R.; Clements, D.; Swinyard, B. M.; Pearson, C.; Farrah, D.; Huang, J.-S.; Alonso-Herrero, A.; Bock, J. J.; Cooray, A.; Griffin, M. J.; Oliver, S.; Smith, A.; Wang, L.; Riechers, D.; Scott, D.; Vaccari, M.; Valtchanov, I.

    2014-01-20

    We report the first results from a spectroscopic survey of the [C II] 158?m line from a sample of intermediate redshift (0.2 luminous infrared galaxies, (U)LIRGs (L {sub IR} > 10{sup 11.5} L {sub ?}), using the Spectral and Photometric Imaging REceiver-Fourier Transform Spectrometer on board the Herschel Space Observatory. This is the first survey of [C II] emission, an important tracer of star formation, at a redshift range where the star formation rate density of the universe increases rapidly. We detect strong [C II] 158?m line emission from over 80% of the sample. We find that the [C II] line is luminous, in the range (0.8-4) 10{sup 3} of the far-infrared continuum luminosity of our sources, and appears to arise from photodissociation regions on the surface of molecular clouds. The L{sub [C} {sub II]}/L {sub IR} ratio in our intermediate redshift (U)LIRGs is on average ?10times larger than that of local ULIRGs. Furthermore, we find that the L{sub [C} {sub II]}/L {sub IR} and L{sub [CII]}/L{sub CO(1-0)} ratios in our sample are similar to those of local normal galaxies and high-z star-forming galaxies. ULIRGs at z ? 0.5 show many similarities to the properties of local normal and high-z star-forming galaxies. Our findings strongly suggest that rapid evolution in the properties of the star-forming regions of (U)LIRGs is likely to have occurred in the last 5 billion years.

  6. Distinct Luminal-Type Mammary Carcinomas Arise from Orthotopic Trp53-Null Mammary Transplantation of Juvenile versus Adult Mice

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Nguyen, David H.; Ouyang, Haoxu; Mao, Jian-Hua; Hlatky, Lynn; Barcellos-Hoff, M. H.

    2014-12-01

    Age and physiologic status, such as menopause, are risk factors for breast cancer. Less clear is what factors influence the diversity of breast cancer. In this study, we investigated the effect of host age on the distribution of tumor subtypes in mouse mammary chimera consisting of wild-type hosts and Trp53 nullizygous epithelium, which undergoes a high rate of neoplastic transformation. Wild-type mammary glands cleared of endogenous epithelium at 3 weeks of age were subsequently transplanted during puberty (5 weeks) or at maturation (10 weeks) with syngeneic Trp53-null mammary tissue fragments and monitored for one year. Tumors arose sooner from adultmore » hosts (AH) compared with juvenile hosts (JH). However, compared with AH tumors, JH tumors grew several times faster, were more perfused, exhibited a two-fold higher mitotic index, and were more highly positive for insulin-like growth factor receptor phosphorylation. Most tumors in each setting were estrogen receptor (ER)-positive (80% JH vs. 70% AH), but JH tumors were significantly more ER-immunoreactive (P = 0.0001) than AH tumors. A differential expression signature (JvA) of juvenile versus adult tumors revealed a luminal transcriptional program. Centroids of the human homologs of JvA genes showed that JH tumors were more like luminal A tumors and AH tumors were more like luminal B tumors. Hierarchical clustering with the JvA human ortholog gene list segregated luminal A and luminal B breast cancers across datasets. Lastly, these data support the notion that age-associated host physiology greatly influences the intrinsic subtype of breast cancer.« less

  7. A far-infrared spectroscopic survey of intermediate redshift (ultra) luminous infrared galaxies

    SciTech Connect (OSTI)

    Magdis, Georgios E.; Rigopoulou, D.; Hopwood, R.; Clements, D.; Huang, J.-S.; Farrah, D.; Pearson, C.; Alonso-Herrero, Almudena; Bock, J. J.; Cooray, A.; Griffin, M. J.; Oliver, S.; Perez Fournon, I.; Riechers, D.; Swinyard, B. M.; Thatte, N.; Scott, D.; Valtchanov, I.; Vaccari, M.

    2014-11-20

    We present Herschel far-IR photometry and spectroscopy as well as ground-based CO observations of an intermediate redshift (0.21 ? z ? 0.88) sample of Herschel-selected (ultra)-luminous infrared galaxies (L {sub IR} > 10{sup 11.5} L {sub ?}). With these measurements, we trace the dust continuum, far-IR atomic line emission, in particular [C II] 157.7 ?m, as well as the molecular gas of z ? 0.3 luminous and ultraluminous infrared galaxies (LIRGs and ULIRGs) and perform a detailed investigation of the interstellar medium of the population. We find that the majority of Herschel-selected intermediate redshift (U)LIRGs have L {sub C} {sub II}/L {sub FIR} ratios that are a factor of about 10 higher than that of local ULIRGs and comparable to that of local normal and high-z star-forming galaxies. Using our sample to bridge local and high-z [C II] observations, we find that the majority of galaxies at all redshifts and all luminosities follow an L {sub C} {sub II}L {sub FIR} relation with a slope of unity, from which local ULIRGs and high- z active-galactic-nucleus-dominated sources are clear outliers. We also confirm that the strong anti-correlation between the L {sub C} {sub II}/L {sub FIR} ratio and the far-IR color L {sub 60}/L {sub 100} observed in the local universe holds over a broad range of redshifts and luminosities, in the sense that warmer sources exhibit lower L {sub C} {sub II}/L {sub FIR} at any epoch. Intermediate redshift ULIRGs are also characterized by large molecular gas reservoirs and by lower star formation efficiencies compared to that of local ULIRGs. The high L {sub C} {sub II}/L {sub FIR} ratios, the moderate star formation efficiencies (L {sub IR}/L{sub CO}{sup ?} or L {sub IR}/M{sub H{sub 2}}), and the relatively low dust temperatures of our sample (which are also common characteristics of high-z star-forming galaxies with ULIRG-like luminosities) indicate that the evolution of the physical properties of (U)LIRGs between the present day and z

  8. Mirant Potomac, Alexandria, Virginia: Maximum Impacts Predicted by

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AERMOD-PRIME | Department of Energy PRIME Mirant Potomac, Alexandria, Virginia: Maximum Impacts Predicted by AERMOD-PRIME Docket No. EO-05-01: Mirant Potomac, Alexandria, Virginia: Maximum Impacts Predicted by AERMOD-PRIME, Compliance based on highest, second-highest, short-term, and highest annual concentrations. Mirant Potomac, Alexandria, Virginia: Maximum Impacts Predicted by AERMOD-PRIME (24.52

  9. Montana Total Maximum Daily Load Development Projects Wiki |...

    Open Energy Info (EERE)

    Wiki Jump to: navigation, search OpenEI Reference LibraryAdd to library Web Site: Montana Total Maximum Daily Load Development Projects Wiki Abstract Provides information on...

  10. Engineer End Uses for Maximum Efficiency | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    for Maximum Efficiency (August 2004) More Documents & Publications Maintaining System Air Quality Compressed Air Storage Strategies Alternative Strategies for Low Pressure End Uses

  11. Laser selection based on maximum permissible exposure limits...

    Office of Scientific and Technical Information (OSTI)

    Laser selection based on maximum permissible exposure limits for visible and middle-near infrared repetitively pulsed lasers. Citation Details In-Document Search Title: Laser ...

  12. redMaGiC. Selecting Luminous Red Galaxies from the DES Science Verification Data

    SciTech Connect (OSTI)

    Rozo, E.

    2015-07-20

    We introduce redMaGiC, an automated algorithm for selecting Luminous Red Galaxies (LRGs). The algorithm was developed to minimize photometric redshift uncertainties in photometric large-scale structure studies. redMaGiC achieves this by self-training the color-cuts necessary to produce a luminosity-thresholded LRG sam- ple of constant comoving density. Additionally, we demonstrate that redMaGiC photo-zs are very nearly as accurate as the best machine-learning based methods, yet they require minimal spectroscopic training, do not suffer from extrapolation biases, and are very nearly Gaussian. We apply our algorithm to Dark Energy Survey (DES) Science Verification (SV) data to produce a redMaGiC catalog sampling the redshift range z ϵ [0.2,0.8]. Our fiducial sample has a comoving space density of 10-3 (h-1Mpc)-3, and a median photo-z bias (zspec zphoto) and scatter (σz=(1 + z)) of 0.005 and 0.017 respectively.The corresponding 5σ outlier fraction is 1.4%. We also test our algorithm with Sloan Digital Sky Survey (SDSS) Data Release 8 (DR8) and Stripe 82 data, and discuss how spectroscopic training can be used to control photo-z biases at the 0.1% level.

  13. Alma observations of nearby luminous infrared galaxies with various agn energetic contributions using dense gas tracers

    SciTech Connect (OSTI)

    Imanishi, Masatoshi; Nakanishi, Kouichiro

    2014-07-01

    We present the results of our ALMA Cycle 0 observations, using HCN/HCO{sup +}/HNC J = 4-3 lines, of six nearby luminous infrared galaxies with various energetic contributions from active galactic nuclei (AGNs) estimated from previous infrared spectroscopy. These lines are very effective for probing the physical properties of high-density molecular gas around the hidden energy sources in the nuclear regions of these galaxies. We find that HCN to HCO{sup +} J = 4-3 flux ratios tend to be higher in AGN-important galaxies than in starburst-dominated regions, as was seen at the J = 1-0 transition, while there is no clear difference in the HCN-to-HNC J = 4-3 flux ratios among observed sources. A galaxy with a starburst-type infrared spectral shape and very large molecular line widths shows a high HCN-to-HCO{sup +} J = 4-3 flux ratio, which could be due to turbulence-induced heating. We propose that enhanced HCN J = 4-3 emission relative to HCO{sup +} J = 4-3 could be used to detect more energetic activity than normal starbursts, including deeply buried AGNs, in dusty galaxy populations.

  14. Discovery of GeV emission from the direction of the luminous infrared galaxy NGC 2146

    SciTech Connect (OSTI)

    Tang, Qing-Wen; Wang, Xiang-Yu [School of Astronomy and Space Science, Nanjing University, Nanjing, 210093 (China); Thomas Tam, Pak-Hin, E-mail: xywang@nju.edu.cn, E-mail: phtam@phys.nthu.edu.tw [Institute of Astronomy and Department of Physics, National Tsing Hua University, Hsinchu 30013, Taiwan (China)

    2014-10-10

    Recent detections of high-energy gamma-ray emission from starburst galaxies M82 and NGC 253 suggest that starburst galaxies are huge reservoirs of cosmic rays and these cosmic rays convert a significant fraction of their energy into gamma-rays by colliding with the dense interstellar medium. In this paper, we report the search for high-energy gamma-ray emission from several nearby star-forming and starburst galaxies using the 68 month data obtained with the Fermi Large Area Telescope. We found a ?5.5? detection of gamma-ray emission above 200 MeV from a source spatially coincident with the location of the luminous infrared galaxy NGC 2146. Also taking into account the temporal and spectral properties of the gamma-ray emission, we suggest that the gamma-ray source is likely to be the counterpart of NGC 2146. The gamma-ray luminosity suggests that cosmic rays in NGC 2146 convert most of their energy into secondary pions, so NGC 2146 is a 'proton calorimeter'. It is also found that NGC 2146 obeys the quasi-linear scaling relation between gamma-ray luminosity and total infrared luminosity for star-forming galaxies, strengthening the connection between massive star formation and gamma-ray emission of star-forming galaxies. Possible TeV emission from NGC 2146 is predicted and the implications for high-energy neutrino emission from starburst galaxies are discussed.

  15. Properties of M31. IV. Candidate luminous blue variables from PAndromeda

    SciTech Connect (OSTI)

    Lee, C.-H.; Seitz, S.; Kodric, M.; Riffeser, A.; Koppenhoefer, J.; Bender, R.; Snigula, J.; Hopp, U.; Gssl, C.; Bianchi, L.; Price, P. A.; Fraser, M.; Burgett, W.; Chambers, K. C.; Flewelling, H.; Kaiser, N.; Kudritzki, R.-P.; Magnier, E. A.; Draper, P. W.

    2014-04-10

    We perform a study on the optical and infrared photometric properties of known luminous blue variables (LBVs) in M31 using a sample of LBV candidates from the Local Group Galaxy Survey by Masset et al. We find that M31 LBV candidates show photometric variability ranging from 0.375 to 1.576 mag in r {sub P1} during a 3 yr time span observed by the Pan-STARRS 1 Andromeda survey (PAndromeda). Their near-infrared colors also follow the distribution of Galactic LBVs as shown by Oksala et al. We use these features as selection criteria to search for unknown LBV candidates in M31. We thus devise a method to search for candidate LBVs using both optical color from the Local Group Galaxy Survey and infrared color from the Two Micron All Sky Survey, as well as photometric variations observed by PAndromeda. We find four sources exhibiting common properties of known LBVs. These sources also exhibit UV emission as seen from Galaxy Evolution Explorer, which is one of the previously adopted methods of searching for LBV candidates. The locations of the LBVs are well aligned with M31 spiral arms as seen in UV light, suggesting that they are evolved stars at a young age given their high-mass nature. We compare these candidates with the latest Geneva evolutionary tracks, which show that our new M31 LBV candidates are massive, evolved stars with ages of 10-100 Myr.

  16. Visual Comfort Analysis of Innovative Interior and Exterior Shading Systems for Commercial Buildings using High Resolution Luminance Images

    SciTech Connect (OSTI)

    Konis, Kyle; Lee, Eleanor; Clear, Robert

    2011-01-11

    The objective of this study was to explore how calibrated high dynamic range (HDR) images (luminance maps) acquired in real world daylit environments can be used to characterize, evaluate, and compare visual comfort conditions of innovative facade shading and light-redirecting systems. Detailed (1536 x 1536 pixel) luminance maps were time-lapse acquired from two view positions in an unoccupied full scale testbed facility. These maps were analyzed using existing visual comfort metrics to quantify how innovative interior and exterior shading systems compare to conventional systems under real sun and sky conditions over a solstice-to-solstice test interval. The results provide a case study in the challenges and potential of methods of visualizing, evaluating and summarizing daily and seasonal variation of visual comfort conditions computed from large sets of image data.

  17. A LUMINOUS, FAST RISING UV-TRANSIENT DISCOVERED BY ROTSE: A TIDAL DISRUPTION EVENT?

    SciTech Connect (OSTI)

    Vink, J.; Wheeler, J. C.; Chatzopoulos, E.; Marion, G. H.; Yuan, F.; Akerlof, C.; Quimby, R. M.; Ramirez-Ruiz, E.; Guillochon, J.

    2015-01-01

    We present follow-up observations of an optical transient (OT) discovered by ROTSE on 2009 January 21. Photometric monitoring was carried out with ROTSE-IIIb in the optical and Swift in the UV up to +70 days after discovery. The light curve showed a fast rise time of ?10 days followed by a steep decline over the next 60 days, which was much faster than that implied by {sup 56}Ni{sup 56}Co radioactive decay. The Sloan Digital Sky Survey Data Release 10 database contains a faint, red object at the position of the OT, which appears slightly extended. This and other lines of evidence suggest that the OT is of extragalactic origin, and this faint object is likely the host galaxy. A sequence of optical spectra obtained with the 9.2m Hobby-Eberly Telescope between +8 and +45 days after discovery revealed a hot, blue continuum with no visible spectral features. A few weak features that appeared after +30 days probably originated from the underlying host. Fitting synthetic templates to the observed spectrum of the host galaxy revealed a redshift of z = 0.19. At this redshift, the peak magnitude of the OT is close to 22.5, similar to the brightest super-luminous supernovae; however, the lack of identifiable spectral features makes the massive stellar death hypothesis less likely. A more plausible explanation appears to be the tidal disruption of a Sun-like star by the central supermassive black hole. We argue that this transient likely belongs to a class of super-Eddington tidal disruption events.

  18. Mirant Potomac, Alexandria, Virginia: Maximum Impacts Predicted by

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AERMOD-PRIME, Units 3, 1, 2 SO2 Case | Department of Energy PRIME, Units 3, 1, 2 SO2 Case Mirant Potomac, Alexandria, Virginia: Maximum Impacts Predicted by AERMOD-PRIME, Units 3, 1, 2 SO2 Case Docket No. EO-05-01: Mirant Potomac, Alexandria, Virginia: Maximum Impacts Predicted by AERMOD-PRIME, Units 3, 1, 2 SO2 Case. Compliance based on highest, second-highest, short-term, and highest annual concentrations. Mirant Potomac, Alexandria, Virginia: Maximum Impacts Predicted by AERMOD-PRIME,

  19. Mirant Potomac, Alexandria, Virginia: Maximum Impacts Predicted by

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AERMOD-PRIME, Units 4, 1, 2 SO2 Case | Department of Energy 4, 1, 2 SO2 Case Mirant Potomac, Alexandria, Virginia: Maximum Impacts Predicted by AERMOD-PRIME, Units 4, 1, 2 SO2 Case Docket No. EO-05-01: Mirant Potomac, Alexandria, Virginia: Maximum Impacts Predicted by AERMOD-PRIME, Units 4, 1, 2 SO2 Case. Compliance based on highest, second-highest, short-term, and highest annual concentrations. Mirant Potomac, Alexandria, Virginia: Maximum Impacts Predicted by AERMOD-PRIME, Units 4, 1, 2

  20. Mirant Potomac, Alexandria, Virginia: Maximum Impacts Predicted by

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AERMOD-PRIME, Units 5, 1, 2 SO2 Case | Department of Energy 5, 1, 2 SO2 Case Mirant Potomac, Alexandria, Virginia: Maximum Impacts Predicted by AERMOD-PRIME, Units 5, 1, 2 SO2 Case Docket No. EO-05-01: Mirant Potomac, Alexandria, Virginia: Maximum Impacts Predicted by AERMOD-PRIME, Units 5, 1, 2 SO2 Case. Compliance based on highest, second-highest, short-term, and highest annual concentrations. Mirant Potomac, Alexandria, Virginia: Maximum Impacts Predicted by AERMOD-PRIME, Units 5, 1, 2

  1. Maximum Photovoltaic Penetration Levels on Typical Distribution Feeders: Preprint

    SciTech Connect (OSTI)

    Hoke, A.; Butler, R.; Hambrick, J.; Kroposki, B.

    2012-07-01

    This paper presents simulation results for a taxonomy of typical distribution feeders with various levels of photovoltaic (PV) penetration. For each of the 16 feeders simulated, the maximum PV penetration that did not result in steady-state voltage or current violation is presented for several PV location scenarios: clustered near the feeder source, clustered near the midpoint of the feeder, clustered near the end of the feeder, randomly located, and evenly distributed. In addition, the maximum level of PV is presented for single, large PV systems at each location. Maximum PV penetration was determined by requiring that feeder voltages stay within ANSI Range A and that feeder currents stay within the ranges determined by overcurrent protection devices. Simulations were run in GridLAB-D using hourly time steps over a year with randomized load profiles based on utility data and typical meteorological year weather data. For 86% of the cases simulated, maximum PV penetration was at least 30% of peak load.

  2. Oxidation State Optimization for Maximum Efficiency of NOx Adsorber

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Catalysts | Department of Energy State Optimization for Maximum Efficiency of NOx Adsorber Catalysts Oxidation State Optimization for Maximum Efficiency of NOx Adsorber Catalysts Presentation given at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010. deer10_li.pdf (1.68 MB) More Documents & Publications Lean NOx Trap Regeneration Selectivity Towards N2O -- Similarities and Differences Between H2, CO and C3H6

  3. Are There Practical Approaches for Achieving the Theoretical Maximum Engine

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Efficiency? | Department of Energy Are There Practical Approaches for Achieving the Theoretical Maximum Engine Efficiency? Are There Practical Approaches for Achieving the Theoretical Maximum Engine Efficiency? 2004 Diesel Engine Emissions Reduction (DEER) Conference Presentation: University of Wisconsin, Madison 2004_deer_foster.pdf (273.98 KB) More Documents & Publications Fuel Modification t Facilitate Future Combustion Regimes? The Next ICE Age The Next ICE Age

  4. Table 10.1 Nonswitchable Minimum and Maximum Consumption, 2002

    U.S. Energy Information Administration (EIA) Indexed Site

    Nonswitchable Minimum and Maximum Consumption, 2002; " " Level: National and Regional Data;" " Row: Energy Sources;" " Column: Consumption Potential;" " Unit: Physical Units." ,,,,"RSE" ,"Actual","Minimum","Maximum","Row" "Energy Sources","Consumption","Consumption(a)","Consumption(b)","Factors" ,"Total United States" "RSE Column

  5. ON THE NATURE OF THE PROTOTYPE LUMINOUS BLUE VARIABLE AG CARINAE. II. WITNESSING A MASSIVE STAR EVOLVING CLOSE TO THE EDDINGTON AND BISTABILITY LIMITS

    SciTech Connect (OSTI)

    Groh, J. H.; Hillier, D. J.; Damineli, A.

    2011-07-20

    We show that the significantly different effective temperatures (T{sub eff}) achieved by the luminous blue variable AG Carinae during the consecutive visual minima of 1985-1990 (T{sub eff} {approx_equal} 22,800 K) and 2000-2001 (T{sub eff} {approx_equal} 17,000 K) place the star on different sides of the bistability limit, which occurs in line-driven stellar winds around T{sub eff} {approx} 21,000 K. Decisive evidence is provided by huge changes in the optical depth of the Lyman continuum in the inner wind as T{sub eff} changes during the S Dor cycle. These changes cause different Fe ionization structures in the inner wind. The bistability mechanism is also related to the different wind parameters during visual minima: the wind terminal velocity was 2-3 times higher and the mass-loss rate roughly two times smaller in 1985-1990 than in 2000-2003. We obtain a projected rotational velocity of 220 {+-} 50 km s{sup -1} during 1985-1990 which, combined with the high luminosity (L{sub *} = 1.5 x 10{sup 6} L{sub sun}), puts AG Car extremely close to the Eddington limit modified by rotation ({Omega}{Gamma} limit): for an inclination angle of 90{sup 0}, {Gamma}{sub {Omega}} {approx}> 1.0 for M{sub sun} {approx}< 60. Based on evolutionary models and mass budget, we obtain an initial mass of {approx}100 M{sub sun} and a current mass of {approx}60-70 M{sub sun} for AG Car. Therefore, AG Car is close to, if not at, the {Omega}{Gamma} limit during visual minimum. Assuming M = 70 M{sub sun}, we find that {Gamma}{sub {Omega}} decreases from 0.93 to 0.72 as AG Car expands toward visual maximum, suggesting that the star is not above the Eddington limit during maximum phases.

  6. The Relation Between Accretion Rate And Jet Power in X-Ray Luminous Elliptical Galaxies

    SciTech Connect (OSTI)

    Allen, Steven W.; Dunn, R.J.H.; Fabian, A.C.; Taylor, G.B.; Reynolds, C.S.; /Maryland U.

    2006-03-10

    Using Chandra X-ray observations of nine nearby, X-ray luminous elliptical galaxies with good optical velocity dispersion measurements, we show that a tight correlation exists between the Bondi accretion rates calculated from the observed gas temperature and density profiles and estimated black hole masses, and the power emerging from these systems in relativistic jets. The jet powers, which are inferred from the energies and timescales required to inflate cavities observed in the surrounding X-ray emitting gas, can be related to the accretion rates using a power law model of the form log (P{sub Bondi}/10{sup 43} erg s{sup -1}) = A + B log (P{sub jet}/10{sup 43} erg s{sup -1}), with A = 0.62 {+-} 0.15 and B = 0.77 {+-} 0.18. Our results show that a significant fraction of the energy associated with the rest mass of material entering the Bondi accretion radius (2.4{sub -0.7}{sup +1.0} per cent, for P{sub jet} = 10{sup 43} erg s{sup -1}) eventually emerges in the relativistic jets. Our results have significant implications for studies of accretion, jet formation and galaxy formation. The observed tight correlation suggests that the Bondi formulae provide a reasonable description of the accretion process in these systems, despite the likely presence of magnetic pressure and angular momentum in the accreting gas. The similarity of the P{sub Bondi} and P{sub jet} values argues that a significant fraction of the matter entering the accretion radius flows down to regions close to the black holes, where the jets are presumably formed. The tight correlation between P{sub Bondi} and P{sub jet} also suggests that the accretion flows are approximately stable over timescales of a few million years. Our results show that the black hole ''engines'' at the hearts of large elliptical galaxies and groups feed back sufficient energy to stem cooling and star formation, leading naturally to the observed exponential cut off at the bright end of the galaxy luminosity function.

  7. A new role of SNAI2 in postlactational involution of the mammary gland links it to luminal breast cancer development

    SciTech Connect (OSTI)

    Castillo-Lluva, Sonia; Hontecillas-Prieto, Lourdes; Blanco-Gómez, Adrian; del Mar Sáez-Freire, María; García-Cenador, Begona; García-Criado, Javier; Pérez-Andrés, Martín; Orfao, Alberto; Cañamero, Marta; Mao, Jian-Hua; Gridley, Thomas; Castellanos-Martín, Andres; Pérez-Losada, Jesus

    2015-06-22

    Breast cancer is a major cause of mortality in women. The transcription factor SNAI2 has been implicated in the pathogenesis of several types of cancer, including breast cancer of basal origin. Here we show that SNAI2 is also important in the development of breast cancer of luminal origin in MMTV-ErbB2 mice. SNAI2 deficiency leads to longer latency and fewer luminal tumors, both of these being characteristics of pretumoral origin. These effects were associated with reduced proliferation and a decreased ability to generate mammospheres in normal mammary glands. However, the capacity to metastasize was not modified. Under conditions of increased ERBB2 oncogenic activity after pregnancy plus SNAI2 deficiency, both pretumoral defects-latency and tumor load-were compensated. However, the incidence of lung metastases was dramatically reduced. Furthermore, SNAI2 was required for proper postlactational involution of the breast. At 3 days post lactational involution, the mammary glands of Snai2-deficient mice exhibited lower levels of pSTAT3 and higher levels of pAKT1, resulting in decreased apoptosis. Abundant noninvoluted ducts were still present at 30 days post lactation, with a greater number of residual ERBB2+ cells. These results suggest that this defect in involution leads to an increase in the number of susceptible target cells for transformation, to the recovery of the capacity to generate mammospheres and to an increase in the number of tumors. In conclusion, our work demonstrates the participation of SNAI2 in the pathogenesis of luminal breast cancer, and reveals an unexpected connection between the processes of postlactational involution and breast tumorigenesis in Snai2-null mutant mice.

  8. EVIDENCE FOR THE DISKY ORIGIN OF LUMINOUS VIRGO DWARF ELLIPTICALS FROM THE KINEMATICS OF THEIR GLOBULAR CLUSTER SYSTEMS

    SciTech Connect (OSTI)

    Beasley, Michael A.; Cenarro, A. Javier; Brodie, Jean P. E-mail: cenarro@iac.es E-mail: brodie@ucolick.org

    2009-06-15

    We report evidence for dynamically significant rotation in the globular cluster systems of two luminous Virgo dwarf ellipticals, VCC1261 and VCC1528. Including previous results for VCC1087, the globular cluster systems of all three Virgo dwarf ellipticals studied in detail to date exhibit v {sub rot}/{sigma}{sub los}>1. Taking the rotation seen in the globular clusters as a maximal disk rotation, and accounting for the possible fading of any hypothetical progenitor galaxy, we find all three dwarf elliptical galaxies (dEs) lie on the r-band Tully-Fisher relation. We argue that these data support the hypothesis that luminous dEs are the remnants of transformed disk galaxies. We also obtained deep, longslit data for the stars in VCC1261 and VCC1528. Both these galaxies show rapid rotation in their inner regions, with spatial scales of {approx}0.5 kpc. These rotation velocities are surprisingly similar to those seen in the globular cluster systems. At larger radii, we see little rotation in the dEs themselves. Since our longslit data for Virgo dEs extend out to 1-2 effective radii (typical of deep observations), whereas the globular clusters extend out to 4-7 effective radii, we conclude that nondetections of rotation in many luminous dEs may simply be due to a lack of radial coverage in the stellar data, and that globular clusters represent singularly sensitive probes of the dynamics of dEs. Based on these data, we suggest that gas disks are significant sites of globular cluster formation in the early universe.

  9. A new role of SNAI2 in postlactational involution of the mammary gland links it to luminal breast cancer development

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Castillo-Lluva, Sonia; Hontecillas-Prieto, Lourdes; Blanco-Gómez, Adrian; del Mar Sáez-Freire, María; García-Cenador, Begona; García-Criado, Javier; Pérez-Andrés, Martín; Orfao, Alberto; Cañamero, Marta; Mao, Jian-Hua; et al

    2015-06-22

    Breast cancer is a major cause of mortality in women. The transcription factor SNAI2 has been implicated in the pathogenesis of several types of cancer, including breast cancer of basal origin. Here we show that SNAI2 is also important in the development of breast cancer of luminal origin in MMTV-ErbB2 mice. SNAI2 deficiency leads to longer latency and fewer luminal tumors, both of these being characteristics of pretumoral origin. These effects were associated with reduced proliferation and a decreased ability to generate mammospheres in normal mammary glands. However, the capacity to metastasize was not modified. Under conditions of increased ERBB2more » oncogenic activity after pregnancy plus SNAI2 deficiency, both pretumoral defects-latency and tumor load-were compensated. However, the incidence of lung metastases was dramatically reduced. Furthermore, SNAI2 was required for proper postlactational involution of the breast. At 3 days post lactational involution, the mammary glands of Snai2-deficient mice exhibited lower levels of pSTAT3 and higher levels of pAKT1, resulting in decreased apoptosis. Abundant noninvoluted ducts were still present at 30 days post lactation, with a greater number of residual ERBB2+ cells. These results suggest that this defect in involution leads to an increase in the number of susceptible target cells for transformation, to the recovery of the capacity to generate mammospheres and to an increase in the number of tumors. In conclusion, our work demonstrates the participation of SNAI2 in the pathogenesis of luminal breast cancer, and reveals an unexpected connection between the processes of postlactational involution and breast tumorigenesis in Snai2-null mutant mice.« less

  10. Quality, precision and accuracy of the maximum No. 40 anemometer

    SciTech Connect (OSTI)

    Obermeir, J.; Blittersdorf, D.

    1996-12-31

    This paper synthesizes available calibration data for the Maximum No. 40 anemometer. Despite its long history in the wind industry, controversy surrounds the choice of transfer function for this anemometer. Many users are unaware that recent changes in default transfer functions in data loggers are producing output wind speed differences as large as 7.6%. Comparison of two calibration methods used for large samples of Maximum No. 40 anemometers shows a consistent difference of 4.6% in output speeds. This difference is significantly larger than estimated uncertainty levels. Testing, initially performed to investigate related issues, reveals that Gill and Maximum cup anemometers change their calibration transfer functions significantly when calibrated in the open atmosphere compared with calibration in a laminar wind tunnel. This indicates that atmospheric turbulence changes the calibration transfer function of cup anemometers. These results call into question the suitability of standard wind tunnel calibration testing for cup anemometers. 6 refs., 10 figs., 4 tabs.

  11. LED Efficacy: What America Stands to Gain | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Efficacy: What America Stands to Gain LED Efficacy: What America Stands to Gain LED Efficacy-What America Stands to Gain_ November 2015.pdf (280.37 KB)

  12. LED Record Efficacy and Brightness

    Broader source: Energy.gov [DOE]

    Designed for general lighting applications such as street, industrial, and parking garage lighting, the Cree XLamp® power LED sets new records for LED brightness and efficacy, up to 85 lm/W at 350 mA. The XLamp utilizes Cree's performance breakthrough EZBright™ LED chip; both products include technology that was developed in part with R&D funding support from DOE.

  13. LITERATURE REVIEW ON MAXIMUM LOADING OF RADIONUCLIDES ON CRYSTALLINE SILICOTITANATE

    SciTech Connect (OSTI)

    Adu-Wusu, K.; Pennebaker, F.

    2010-10-13

    Plans are underway to use small column ion exchange (SCIX) units installed in high-level waste tanks to remove Cs-137 from highly alkaline salt solutions at Savannah River Site. The ion exchange material slated for the SCIX project is engineered or granular crystalline silicotitanate (CST). Information on the maximum loading of radionuclides on CST is needed by Savannah River Remediation for safety evaluations. A literature review has been conducted that culminated in the estimation of the maximum loading of all but one of the radionuclides of interest (Cs-137, Sr-90, Ba-137m, Pu-238, Pu-239, Pu-240, Pu-241, Am-241, and Cm-244). No data was found for Cm-244.

  14. Industry guidelines for the calibration of maximum anemometers

    SciTech Connect (OSTI)

    Bailey, B.H.

    1996-12-31

    The purpose of this paper is to report on a framework of guidelines for the calibration of the Maximum Type 40 anemometer. This anemometer model is the wind speed sensor of choice in the majority of wind resource assessment programs in the U.S. These guidelines were established by the Utility Wind Resource Assessment Program. In addition to providing guidelines for anemometers, the appropriate use of non-calibrated anemometers is also discussed. 14 refs., 1 tab.

  15. Maximum patch method for directional dark matter detection

    SciTech Connect (OSTI)

    Henderson, Shawn; Monroe, Jocelyn; Fisher, Peter [Department of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139 (United States); Laboratory for Nuclear Science, MIT Kavli Institute for Astrophysics and Space Research, Department of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139 (United States)

    2008-07-01

    Present and planned dark matter detection experiments search for WIMP-induced nuclear recoils in poorly known background conditions. In this environment, the maximum gap statistical method provides a way of setting more sensitive cross section upper limits by incorporating known signal information. We give a recipe for the numerical calculation of upper limits for planned directional dark matter detection experiments, that will measure both recoil energy and angle, based on the gaps between events in two-dimensional phase space.

  16. Maximum entanglement in squeezed boson and fermion states

    SciTech Connect (OSTI)

    Khanna, F. C.; Malbouisson, J. M. C.; Santana, A. E.; Santos, E. S.

    2007-08-15

    A class of squeezed boson and fermion states is studied with particular emphasis on the nature of entanglement. We first investigate the case of bosons, considering two-mode squeezed states. Then we construct the fermion version to show that such states are maximum entangled, for both bosons and fermions. To achieve these results, we demonstrate some relations involving squeezed boson states. The generalization to the case of fermions is made by using Grassmann variables.

  17. Maximum Entry and Mandatory Separation Ages for Certain Security Employees

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2001-10-11

    The policy establishes the DOE policy on maximum entry and mandatory separation ages for primary or secondary positions covered under special statutory retirement provisions and for those employees whose primary duties are the protection of officials of the United States against threats to personal safety or the investigation, apprehension, and detention of individuals suspected or convicted of offenses against the criminal laws of the United States. Admin Chg 1, dated 12-1-11, supersedes DOE P 310.1.

  18. Possible dynamical explanations for Paltridge's principle of maximum entropy production

    SciTech Connect (OSTI)

    Virgo, Nathaniel Ikegami, Takashi

    2014-12-05

    Throughout the history of non-equilibrium thermodynamics a number of theories have been proposed in which complex, far from equilibrium flow systems are hypothesised to reach a steady state that maximises some quantity. Perhaps the most celebrated is Paltridge's principle of maximum entropy production for the horizontal heat flux in Earth's atmosphere, for which there is some empirical support. There have been a number of attempts to derive such a principle from maximum entropy considerations. However, we currently lack a more mechanistic explanation of how any particular system might self-organise into a state that maximises some quantity. This is in contrast to equilibrium thermodynamics, in which models such as the Ising model have been a great help in understanding the relationship between the predictions of MaxEnt and the dynamics of physical systems. In this paper we show that, unlike in the equilibrium case, Paltridge-type maximisation in non-equilibrium systems cannot be achieved by a simple dynamical feedback mechanism. Nevertheless, we propose several possible mechanisms by which maximisation could occur. Showing that these occur in any real system is a task for future work. The possibilities presented here may not be the only ones. We hope that by presenting them we can provoke further discussion about the possible dynamical mechanisms behind extremum principles for non-equilibrium systems, and their relationship to predictions obtained through MaxEnt.

  19. Reduction in maximum time uncertainty of paired time signals

    DOE Patents [OSTI]

    Theodosiou, G.E.; Dawson, J.W.

    1983-10-04

    Reduction in the maximum time uncertainty (t[sub max]--t[sub min]) of a series of paired time signals t[sub 1] and t[sub 2] varying between two input terminals and representative of a series of single events where t[sub 1][<=]t[sub 2] and t[sub 1]+t[sub 2] equals a constant, is carried out with a circuit utilizing a combination of OR and AND gates as signal selecting means and one or more time delays to increase the minimum value (t[sub min]) of the first signal t[sub 1] closer to t[sub max] and thereby reduce the difference. The circuit may utilize a plurality of stages to reduce the uncertainty by factors of 20--800. 6 figs.

  20. Reduction in maximum time uncertainty of paired time signals

    DOE Patents [OSTI]

    Theodosiou, George E.; Dawson, John W.

    1983-01-01

    Reduction in the maximum time uncertainty (t.sub.max -t.sub.min) of a series of paired time signals t.sub.1 and t.sub.2 varying between two input terminals and representative of a series of single events where t.sub.1 .ltoreq.t.sub.2 and t.sub.1 +t.sub.2 equals a constant, is carried out with a circuit utilizing a combination of OR and AND gates as signal selecting means and one or more time delays to increase the minimum value (t.sub.min) of the first signal t.sub.1 closer to t.sub.max and thereby reduce the difference. The circuit may utilize a plurality of stages to reduce the uncertainty by factors of 20-800.

  1. Reduction in maximum time uncertainty of paired time signals

    DOE Patents [OSTI]

    Theodosiou, G.E.; Dawson, J.W.

    1981-02-11

    Reduction in the maximum time uncertainty (t/sub max/ - t/sub min/) of a series of paired time signals t/sub 1/ and t/sub 2/ varying between two input terminals and representative of a series of single events where t/sub 1/ less than or equal to t/sub 2/ and t/sub 1/ + t/sub 2/ equals a constant, is carried out with a circuit utilizing a combination of OR and AND gates as signal selecting means and one or more time delays to increase the minimum value (t/sub min/) of the first signal t/sub 1/ closer to t/sub max/ and thereby reduce the difference. The circuit may utilize a plurality of stages to reduce the uncertainty by factors of 20 to 800.

  2. Speech processing using conditional observable maximum likelihood continuity mapping

    DOE Patents [OSTI]

    Hogden, John; Nix, David

    2004-01-13

    A computer implemented method enables the recognition of speech and speech characteristics. Parameters are initialized of first probability density functions that map between the symbols in the vocabulary of one or more sequences of speech codes that represent speech sounds and a continuity map. Parameters are also initialized of second probability density functions that map between the elements in the vocabulary of one or more desired sequences of speech transcription symbols and the continuity map. The parameters of the probability density functions are then trained to maximize the probabilities of the desired sequences of speech-transcription symbols. A new sequence of speech codes is then input to the continuity map having the trained first and second probability function parameters. A smooth path is identified on the continuity map that has the maximum probability for the new sequence of speech codes. The probability of each speech transcription symbol for each input speech code can then be output.

  3. Maximum Likelihood Analysis of Low Energy CDMS II Germanium Data

    SciTech Connect (OSTI)

    Agnese, R.

    2015-03-30

    We report on the results of a search for a Weakly Interacting Massive Particle (WIMP) signal in low-energy data of the Cryogenic Dark Matter Search experiment using a maximum likelihood analysis. A background model is constructed using GEANT4 to simulate the surface-event background from Pb210decay-chain events, while using independent calibration data to model the gamma background. Fitting this background model to the data results in no statistically significant WIMP component. In addition, we also perform fits using an analytic ad hoc background model proposed by Collar and Fields, who claimed to find a large excess of signal-like events in our data. Finally, we confirm the strong preference for a signal hypothesis in their analysis under these assumptions, but excesses are observed in both single- and multiple-scatter events, which implies the signal is not caused by WIMPs, but rather reflects the inadequacy of their background model.

  4. Property:Maximum Velocity with Constriction(m/s) | Open Energy...

    Open Energy Info (EERE)

    Velocity with Constriction(ms) Jump to: navigation, search Property Name Maximum Velocity with Constriction(ms) Property Type String Pages using the property "Maximum Velocity...

  5. Tunable THz Generation by the Interaction of a Super-luminous Laser Pulse with Biased Semiconductor Plasma

    SciTech Connect (OSTI)

    Papadopoulos, K.; Zigler, A.

    2006-01-03

    Terahertz (THz) radiation is electromagnetic radiation in the range between several hundred and a few thousand GHz. It covers the gap between fast-wave electronics (millimeter waves) and optics (infrared). This spectral region offers enormous potential for detection of explosives and chemical/biological agents, non-destructive testing of non-metallic structural materials and coatings of aircraft structures, medical imaging, bio-sensing of DNA stretching modes and high-altitude secure communications. The development of these applications has been hindered by the lack of powerful, tunable THz sources with controlled waveform. The need for such sources is accentuated by the strong, but selective absorption of THz radiation during transmission through air with high vapor content. The majority of the current experimental work relies on time-domain spectroscopy using fast electrically biased photoconductive sources in conjunction with femto-second mode-locked Ti:Sapphire lasers. These sources known as Large Aperture Photoconductive Antennas (LAPA) have very limited tunability, relatively low upper bound of power and no bandwidth control. The paper presents a novel source of THz radiation known as Miniature Photoconductive Capacitor Array (MPCA). Experiments demonstrated tunability between .1 - 2 THz, control of the relative bandwidth {delta}f/f between .5-.01, and controlled pulse length and pulse waveform (temporal shape, chirp, pulse-to-pulse modulation etc.). Direct scaling from the current device indicates efficiency in excess of 30% at 1 THz with 1/f2 scaling at higher frequencies, peak power of 100 kW and average power between .1-1 W. The physics underlying the MPCA is the interaction of a super-luminous ionization front generated by the oblique incidence of a Ti:Sapphire laser pulse on a semiconductor crystal (ZnSe) biased with an alternating electrostatic field, similar to that of a frozen wave generator. It is shown theoretically and experimentally that the

  6. LANDFILL OPERATION FOR CARBON SEQUESTRATION AND MAXIMUM METHANE EMISSION CONTROL

    SciTech Connect (OSTI)

    Don Augenstein

    2001-02-01

    The work described in this report, to demonstrate and advance this technology, has used two demonstration-scale cells of size (8000 metric tons [tonnes]), sufficient to replicate many heat and compaction characteristics of larger ''full-scale'' landfills. An enhanced demonstration cell has received moisture supplementation to field capacity. This is the maximum moisture waste can hold while still limiting liquid drainage rate to minimal and safely manageable levels. The enhanced landfill module was compared to a parallel control landfill module receiving no moisture additions. Gas recovery has continued for a period of over 4 years. It is quite encouraging that the enhanced cell methane recovery has been close to 10-fold that experienced with conventional landfills. This is the highest methane recovery rate per unit waste, and thus progress toward stabilization, documented anywhere for such a large waste mass. This high recovery rate is attributed to moisture, and elevated temperature attained inexpensively during startup. Economic analyses performed under Phase I of this NETL contract indicate ''greenhouse cost effectiveness'' to be excellent. Other benefits include substantial waste volume loss (over 30%) which translates to extended landfill life. Other environmental benefits include rapidly improved quality and stabilization (lowered pollutant levels) in liquid leachate which drains from the waste.

  7. Maximum Likelihood Analysis of Low Energy CDMS II Germanium Data

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Agnese, R.

    2015-03-30

    We report on the results of a search for a Weakly Interacting Massive Particle (WIMP) signal in low-energy data of the Cryogenic Dark Matter Search experiment using a maximum likelihood analysis. A background model is constructed using GEANT4 to simulate the surface-event background from Pb210decay-chain events, while using independent calibration data to model the gamma background. Fitting this background model to the data results in no statistically significant WIMP component. In addition, we also perform fits using an analytic ad hoc background model proposed by Collar and Fields, who claimed to find a large excess of signal-like events in ourmore » data. Finally, we confirm the strong preference for a signal hypothesis in their analysis under these assumptions, but excesses are observed in both single- and multiple-scatter events, which implies the signal is not caused by WIMPs, but rather reflects the inadequacy of their background model.« less

  8. Estimate of Maximum Underground Working Gas Storage Capacity in the United States

    Reports and Publications (EIA)

    2006-01-01

    This report examines the aggregate maximum capacity for U.S. natural gas storage. Although the concept of maximum capacity seems quite straightforward, there are numerous issues that preclude the determination of a definitive maximum volume. The report presents three alternative estimates for maximum capacity, indicating appropriate caveats for each.

  9. Boiler Maximum Achievable Control Technology (MACT) Technical Assistance- Fact Sheet, April 2015

    Broader source: Energy.gov [DOE]

    Fact sheet about the Boiler Maximum Achievable Control Technology (MACT) Technical Assistance Program

  10. A search for moderate-redshift survivors from the population of luminous compact passive galaxies at high redshift

    SciTech Connect (OSTI)

    Stockton, Alan; Shih, Hsin-Yi; Larson, Kirsten; Mann, Andrew W. E-mail: hsshih@ifa.hawaii.edu E-mail: amann@ifa.hawaii.edu

    2014-01-10

    From a search of a ∼2400 deg{sup 2} region covered by both the Sloan Digital Sky Survey and UKIRT Infrared Deep Sky Survey databases, we have attempted to identify galaxies at z ∼ 0.5 that are consistent with their being essentially unmodified examples of the luminous passive compact galaxies found at z ∼ 2.5. After isolating good candidates via deeper imaging, we further refine the sample with Keck moderate-resolution spectroscopy and laser guide star adaptive-optics imaging. For four of the five galaxies that so far remain after passing through this sieve, we analyze plausible star-formation histories based on our spectra in order to identify galaxies that may have survived with little modification from the population formed at high redshift. We find two galaxies that are consistent with having formed ≳ 95% of their mass at z > 5. We attempt to estimate masses both from our stellar population determinations and from velocity dispersions. Given the high frequency of small axial ratios, both in our small sample and among samples found at high redshifts, we tentatively suggest that some of the more extreme examples of passive compact galaxies may have prolate morphologies.

  11. XMM-NEWTON OBSERVATIONS OF LUMINOUS SOURCES IN NEARBY GALAXIES NGC 4395, NGC 4736, AND NGC 4258

    SciTech Connect (OSTI)

    Akyuz, A.; Avdan, H.; Kayaci, S.; Ozel, M. E.; Sonbas, E.; Balman, S.

    2013-03-15

    We present the results of a study of non-nuclear discrete sources in a sample of three nearby spiral galaxies (NGC 4395, NGC 4736, and NGC 4258) based on XMM-Newton archival data supplemented with Chandra data for spectral and timing analyses. A total of 75 X-ray sources have been detected within the D{sub 25} regions of the target galaxies. The large collecting area of XMM-Newton makes the statistics sufficient to obtain spectral fitting for 16 (about 20%) of these sources. Compiling the extensive archival exposures available, we were able to obtain the detailed spectral shapes of diverse classes of point sources. We have also studied temporal properties of these luminous sources. Eleven of them are found to show short-term (less than 80 ks) variation while eight of them show long-term variation within factors of {approx}2-5 during a time interval of {approx}2-12 years. Timing analysis provides strong evidence that most of these sources are accreting X-ray binary systems. One source that has properties different from others was suspected to be a supernova remnant, and our follow-up optical observation confirmed this. Our results indicate that sources within the three nearby galaxies are showing a variety of source populations, including several ultraluminous X-ray sources, X-ray binaries, transients together with a super soft source, and a background active galactic nucleus candidate.

  12. The Efficacy of Galaxy Shape Parameters in Photometric Redshift...

    Office of Scientific and Technical Information (OSTI)

    Journal Article: The Efficacy of Galaxy Shape Parameters in Photometric Redshift Estimation: A Neural Network Approach Citation Details In-Document Search Title: The Efficacy of ...

  13. LANDFILL OPERATION FOR CARBON SEQUESTRATION AND MAXIMUM METHANE EMISSION CONTROL

    SciTech Connect (OSTI)

    Don Augenstein; Ramin Yazdani; Rick Moore; Michelle Byars; Jeff Kieffer; Professor Morton Barlaz; Rinav Mehta

    2000-02-26

    Controlled landfilling is an approach to manage solid waste landfills, so as to rapidly complete methane generation, while maximizing gas capture and minimizing the usual emissions of methane to the atmosphere. With controlled landfilling, methane generation is accelerated to more rapid and earlier completion to full potential by improving conditions (principally moisture, but also temperature) to optimize biological processes occurring within the landfill. Gas is contained through use of surface membrane cover. Gas is captured via porous layers, under the cover, operated at slight vacuum. A field demonstration project has been ongoing under NETL sponsorship for the past several years near Davis, CA. Results have been extremely encouraging. Two major benefits of the technology are reduction of landfill methane emissions to minuscule levels, and the recovery of greater amounts of landfill methane energy in much shorter times, more predictably, than with conventional landfill practice. With the large amount of US landfill methane generated, and greenhouse potency of methane, better landfill methane control can play a substantial role both in reduction of US greenhouse gas emissions and in US renewable energy. The work described in this report, to demonstrate and advance this technology, has used two demonstration-scale cells of size (8000 metric tons [tonnes]), sufficient to replicate many heat and compaction characteristics of larger ''full-scale'' landfills. An enhanced demonstration cell has received moisture supplementation to field capacity. This is the maximum moisture waste can hold while still limiting liquid drainage rate to minimal and safely manageable levels. The enhanced landfill module was compared to a parallel control landfill module receiving no moisture additions. Gas recovery has continued for a period of over 4 years. It is quite encouraging that the enhanced cell methane recovery has been close to 10-fold that experienced with conventional

  14. BLACK HOLE MASS ESTIMATES AND RAPID GROWTH OF SUPERMASSIVE BLACK HOLES IN LUMINOUS z ∼ 3.5 QUASARS

    SciTech Connect (OSTI)

    Zuo, Wenwen; Wu, Xue-Bing; Fan, Xiaohui; Green, Richard; Wang, Ran; Bian, Fuyan

    2015-02-01

    We present new near-infrared (IR) observations of the Hβ λ4861 and Mg II λ2798 lines for 32 luminous quasars with 3.2 < z < 3.9 using the Palomar Hale 200 inch telescope and the Large Binocular Telescope. We find that the Mg II FWHM is well correlated with the Hβ FWHM, confirming itself as a good substitute for the Hβ FWHM in the black hole mass estimates. The continuum luminosity at 5100 Å well correlates with the continuum luminosity at 3000 Å and the broad emission line luminosities (Hβ and Mg II). With simultaneous near-IR spectroscopy of the Hβ and Mg II lines to exclude the influences of flux variability, we are able to evaluate the reliability of estimating black hole masses based on the Mg II line for high redshift quasars. With the reliable Hβ line based black hole mass and Eddington ratio estimates, we find that the z ∼ 3.5 quasars in our sample have black hole masses 1.90 × 10{sup 9} M {sub ☉} ≲ M {sub BH} ≲ 1.37 × 10{sup 10} M {sub ☉}, with a median of ∼5.14 × 10{sup 9} M {sub ☉} and are accreting at Eddington ratios between 0.30 and 3.05, with a median of ∼1.12. Assuming a duty cycle of 1 and a seed black hole mass of 10{sup 4} M {sub ☉}, we show that the z ∼ 3.5 quasars in this sample can grow to their estimated black hole masses within the age of the universe at their redshifts.

  15. A multi-wavelength view of the central kiloparsec region in the luminous infrared galaxy NGC 1614

    SciTech Connect (OSTI)

    Herrero-Illana, Rubén; Pérez-Torres, Miguel Á.; Alberdi, Antxon; Hernández-García, Lorena; Alonso-Herrero, Almudena; Colina, Luis; Efstathiou, Andreas; Miralles-Caballero, Daniel; Väisänen, Petri; Packham, Christopher C.; Rajpaul, Vinesh; Zijlstra, Albert A.

    2014-05-10

    The Luminous Infrared Galaxy NGC 1614 hosts a prominent circumnuclear ring of star formation. However, the nature of the dominant emitting mechanism in its central ∼100 pc is still under debate. We present sub-arcsecond angular resolution radio, mid-infrared, Paα, optical, and X-ray observations of NGC 1614, aimed at studying in detail both the circumnuclear ring and the nuclear region. The 8.4 GHz continuum emission traced by the Very Large Array and the Gemini/T-ReCS 8.7 μm emission, as well as the Paα line emission, show remarkable morphological similarities within the star-forming ring, suggesting that the underlying emission mechanisms are tightly related. We used a Hubble Space Telescope/NICMOS Paα map of similar resolution to our radio maps to disentangle the thermal free-free and non-thermal synchrotron radio emission, from which we obtained the intrinsic synchrotron power law for each individual region within the central kiloparsec of NGC 1614. The radio ring surrounds a relatively faint, steep-spectrum source at the very center of the galaxy, suggesting that the central source is not powered by an active galactic nucleus (AGN), but rather by a compact (r ≲ 90 pc) starburst (SB). Chandra X-ray data also show that the central kiloparsec region is dominated by SB activity, without requiring the existence of an AGN. We also used publicly available infrared data to model-fit the spectral energy distribution of both the SB ring and a putative AGN in NGC 1614. In summary, we conclude that there is no need to invoke an AGN to explain the observed bolometric properties of the galaxy.

  16. Property:Maximum Wave Height(m) at Wave Period(s) | Open Energy...

    Open Energy Info (EERE)

    at Wave Period(s) Jump to: navigation, search Property Name Maximum Wave Height(m) at Wave Period(s) Property Type String Pages using the property "Maximum Wave Height(m) at Wave...

  17. 2011-07 "Maximum Utilization of WIPP by Increasing MDA G TRU...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    7 "Maximum Utilization of WIPP by Increasing MDA G TRU Shipments" 2011-07 "Maximum Utilization of WIPP by Increasing MDA G TRU Shipments" The intent of this recommendation is to ...

  18. Normal and tumor-derived myoepithelial cells differ in their ability to interact with luminal breast epithelial cells for polarity and basement membrane deposition

    SciTech Connect (OSTI)

    Gudjonsson, Thorarinn; Ronnov-Jessen, Lone; Villadsen, Rene; Rank, Fritz; Bissell, Mina J.; Petersen, Ole William

    2001-10-04

    The signals that determine the correct polarity of breast epithelial structures in vivo are not understood. We have shown previously that luminal epithelial cells can be polarized when cultured within a reconstituted basement membrane gel. We reasoned that such cues in vivo may be given by myoepithelial cells. Accordingly, we used an assay where luminal epithelial cells are incorrectly polarized to test this hypothesis. We show that culturing human primary luminal epithelial cells within collagen-I gels leads to formation of structures with no lumina and with reverse polarity as judged by dual stainings for sialomucin, epithelial specific antigen or occludin. No basement membrane is deposited, and {beta}4-integrin staining is negative. Addition of purified human myoepithelial cells isolated from normal glands corrects the inverse polarity, and leads to formation of double-layered acini with central lumina. Among the laminins present in the human breast basement membrane (laminin-1, -5 and -10/11), laminin-1 was unique in its ability to substitute for myoepithelial cells in polarity reversal. Myoepithelial cells were purified also from four different breast cancer sources including a biphasic cell line. Three out of four samples either totally lacked the ability to interact with luminal epithelial cells, or conveyed only correction of polarity in a fraction of acini. This behavior was directly related to the ability of the tumor myoepithelial cells to produce {alpha}-1 chain of laminin. In vivo, breast carcinomas were either negative for laminin-1 (7/12 biopsies) or showed a focal, fragmented deposition of a less intensely stained basement membrane (5/12 biopsies). Dual staining with myoepithelial markers revealed that tumorassociated myoepithelial cells were either negative or weakly positive for expression of laminin-1, establishing a strong correlation between loss of laminin-1 and breast cancer. We conclude that the double-layered breast acinus may be

  19. Maximum allowable hydraulic ram force for heel jet removal Tank 241-C-106

    SciTech Connect (OSTI)

    PAULSEN, S.S.

    2003-01-10

    This document contains an evaluation of the maximum force that can be used to actuate the hydraulic ram assembly without causing permanent damage to the riser or pit.

  20. Alaska Maximum Number of Active Crews Engaged in Three-Dimensional...

    Gasoline and Diesel Fuel Update (EIA)

    Three-Dimensional Seismic Surveying (Number of Elements) Alaska Maximum Number of Active Crews Engaged in Three-Dimensional Seismic Surveying (Number of Elements) Year Jan Feb Mar...

  1. A comparison of the morphological properties between local and z ∼ 1 infrared luminous galaxies: Are local and high-z (U)LIRGs different?

    SciTech Connect (OSTI)

    Hung, Chao-Ling; Sanders, D. B.; Larson, Kirsten L.; Lee, Nicholas; Li, Yanxia; Lockhart, Kelly; Shih, Hsin-Yi; Barnes, Joshua E.; Casey, Caitlin M.; Koss, Michael; Kartaltepe, Jeyhan S.; Smith, Howard A.

    2014-08-10

    Ultraluminous and luminous infrared galaxies (ULIRGs and LIRGs) are the most extreme star-forming galaxies in the universe and dominate the total star formation rate density at z > 1. In the local universe (z < 0.3), the majority of ULIRGs and a significant portion of LIRGs are triggered by interactions between gas-rich spiral galaxies, yet it is unclear if this is still the case at high z. To investigate the relative importance of galaxy interactions in infrared luminous galaxies, we carry out a comparison of optical morphological properties between local (U)LIRGs and (U)LIRGs at z = 0.5-1.5 based on the same sample selection, morphology classification scheme, and optical morphology at similar rest-frame wavelengths. In addition, we quantify the systematics in comparing local and high-z data sets by constructing a redshifted data set from local (U)LIRGs, in which its data quality mimics the high-z data set. Based on the Gini-M{sub 20} classification scheme, we find that the fraction of interacting systems decreases by ∼8% from local to z ≲ 1, and it is consistent with the reduction between local and redshifted data sets (6{sub −6}{sup +14}%). Based on visual classifications, the merger fraction of local ULIRGs is found to be ∼20% lower compared to published results, and the reduction due to redshifting is 15{sub −8}{sup +10}%. Consequently, the differences of merger fractions between local and z ≲ 1 (U)LIRGs is only ∼17%. These results demonstrate that there is no strong evolution in the fraction of (U)LIRGs classified as mergers at least out to z ∼ 1. At z > 1, the morphology types of ∼30% of (U)LIRGs cannot be determined due to their faintness in the F814W band; thus, the merger fraction measured at z > 1 suffers from large uncertainties.

  2. Gemini long-slit observations of luminous obscured quasars: Further evidence for an upper limit on the size of the narrow-line region

    SciTech Connect (OSTI)

    Hainline, Kevin N.; Hickox, Ryan C.; Greene, Jenny E.; Myers, Adam D.; Zakamska, Nadia L.; Liu, Guilin; Liu, Xin

    2014-05-20

    We examine the spatial extent of the narrow-line regions (NLRs) of a sample of 30 luminous obscured quasars at 0.4 < z < 0.7 observed with spatially resolved Gemini-N GMOS long-slit spectroscopy. Using the [O III] ?5007 emission feature, we estimate the size of the NLR using a cosmology-independent measurement: the radius where the surface brightness falls to 10{sup 15} erg s{sup 1} cm{sup 2} arcsec{sup 2}. We then explore the effects of atmospheric seeing on NLR size measurements and conclude that direct measurements of the NLR size from observed profiles are too large by 0.1-0.2 dex on average, as compared to measurements made to best-fit Srsic or Voigt profiles convolved with the seeing. These data, which span a full order of magnitude in IR luminosity (log (L {sub 8} {sub ?m}/erg s{sup 1}) = 44.4-45.4), also provide strong evidence that there is a flattening of the relationship between NLR size and active galactic nucleus luminosity at a seeing-corrected size of ?7 kpc. The objects in this sample have high luminosities which place them in a previously under-explored portion of the size-luminosity relationship. These results support the existence of a maximal size of the NLR around luminous quasars; beyond this size, there is either not enough gas or the gas is over-ionized and does not produce enough [O III] ?5007 emission.

  3. U.S. Lower 48 States Offshore Maximum Number of Active Crews...

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    Offshore Maximum Number of Active Crews Engaged in Seismic Surveying (Number of Elements) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 2000's 167...

  4. U.S. Lower 48 States Onshore Maximum Number of Active Crews Engaged...

    Gasoline and Diesel Fuel Update (EIA)

    Onshore Maximum Number of Active Crews Engaged in Seismic Surveying (Number of Elements) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 2000's 435 512...

  5. U.S. Maximum Number of Active Crews Engaged in Seismic Surveying...

    Gasoline and Diesel Fuel Update (EIA)

    Maximum Number of Active Crews Engaged in Seismic Surveying (Number of Elements) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 2000's 615 717 624 481...

  6. Title 43 CFR 3206.12 What are the Minimum and Maximum Lease Sizes...

    Open Energy Info (EERE)

    .12 What are the Minimum and Maximum Lease Sizes? Jump to: navigation, search OpenEI Reference LibraryAdd to library Legal Document- Federal RegulationFederal Regulation: Title 43...

  7. Alaska Maximum Number of Active Crews Engaged in Two-Dimensional...

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    Two-Dimensional Seismic Surveying (Number of Elements) Alaska Maximum Number of Active Crews Engaged in Two-Dimensional Seismic Surveying (Number of Elements) Year Jan Feb Mar Apr...

  8. A Requirement for Significant Reduction in the Maximum BTU Input Rate of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Decorative Vented Gas Fireplaces Would Impose Substantial Burdens on Manufacturers | Department of Energy A Requirement for Significant Reduction in the Maximum BTU Input Rate of Decorative Vented Gas Fireplaces Would Impose Substantial Burdens on Manufacturers A Requirement for Significant Reduction in the Maximum BTU Input Rate of Decorative Vented Gas Fireplaces Would Impose Substantial Burdens on Manufacturers Comment that a requirement to reduce the BTU input rate of existing decorative

  9. Heterogeneity-corrected vs -uncorrected critical structure maximum point doses in breast balloon brachytherapy

    SciTech Connect (OSTI)

    Kim, Leonard; Narra, Venkat; Yue, Ning

    2013-07-01

    Recent studies have reported potentially clinically meaningful dose differences when heterogeneity correction is used in breast balloon brachytherapy. In this study, we report on the relationship between heterogeneity-corrected and -uncorrected doses for 2 commonly used plan evaluation metrics: maximum point dose to skin surface and maximum point dose to ribs. Maximum point doses to skin surface and ribs were calculated using TG-43 and Varian Acuros for 20 patients treated with breast balloon brachytherapy. The results were plotted against each other and fit with a zero-intercept line. Max skin dose (Acuros) = max skin dose (TG-43) ? 0.930 (R{sup 2} = 0.995). The average magnitude of difference from this relationship was 1.1% (max 2.8%). Max rib dose (Acuros) = max rib dose (TG-43) ? 0.955 (R{sup 2} = 0.9995). The average magnitude of difference from this relationship was 0.7% (max 1.6%). Heterogeneity-corrected maximum point doses to the skin surface and ribs were proportional to TG-43-calculated doses. The average deviation from proportionality was 1%. The proportional relationship suggests that a different metric other than maximum point dose may be needed to obtain a clinical advantage from heterogeneity correction. Alternatively, if maximum point dose continues to be used in recommended limits while incorporating heterogeneity correction, institutions without this capability may be able to accurately estimate these doses by use of a scaling factor.

  10. New Funding Opportunity: High-Efficacy Lamp Product Development...

    Office of Environmental Management (EM)

    January 1, 2020. ET's Lighting Alternatives Maximizing Performance and Suitability (LAMPS) program seeks to create suitable high-efficacy lighting options for incandescent ...

  11. ULTRALUMINOUS STAR-FORMING GALAXIES AND EXTREMELY LUMINOUS WARM MOLECULAR HYDROGEN EMISSION AT z = 2.16 IN THE PKS 1138-26 RADIO GALAXY PROTOCLUSTER

    SciTech Connect (OSTI)

    Ogle, P.; Davies, J. E.; Helou, G.; Appleton, P. N.; Bertincourt, B.; Seymour, N.

    2012-05-20

    A deep Spitzer Infrared Spectrograph map of the PKS 1138-26 galaxy protocluster reveals ultraluminous polycyclic aromatic hydrocarbon (PAH) emission from obscured star formation in three protocluster galaxies, including H{alpha}-emitter (HAE) 229, HAE 131, and the central Spiderweb Galaxy. Star formation rates of {approx}500-1100 M{sub Sun} yr{sup -1} are estimated from the 7.7 {mu}m PAH feature. At such prodigious formation rates, the galaxy stellar masses will double in 0.6-1.1 Gyr. We are viewing the peak epoch of star formation for these protocluster galaxies. However, it appears that extinction of H{alpha} is much greater (up to a factor of 40) in the two ULIRG HAEs compared to the Spiderweb. This may be attributed to different spatial distributions of star formation-nuclear star formation in the HAEs versus extended star formation in accreting satellite galaxies in the Spiderweb. We find extremely luminous mid-IR rotational line emission from warm molecular hydrogen in the Spiderweb Galaxy, with L(H{sub 2} 0-0 S(3)) = 1.4 Multiplication-Sign 10{sup 44} erg s{sup -1} (3.7 Multiplication-Sign 10{sup 10} L{sub Sun }), {approx}20 times more luminous than any previously known H{sub 2} emission galaxy (MOHEG). Depending on the temperature, this corresponds to a very large mass of >9 Multiplication-Sign 10{sup 6}-2 Multiplication-Sign 10{sup 9} M{sub Sun} of T > 300 K molecular gas, which may be heated by the PKS 1138-26 radio jet, acting to quench nuclear star formation. There is >8 times more warm H{sub 2} at these temperatures in the Spiderweb than what has been seen in low-redshift (z < 0.2) radio galaxies, indicating that the Spiderweb may have a larger reservoir of molecular gas than more evolved radio galaxies. This is the highest redshift galaxy yet in which warm molecular hydrogen has been directly detected.

  12. Verification of maximum impact force for interim storage cask for the Fast Flux Testing Facility

    SciTech Connect (OSTI)

    Chen, W.W.; Chang, S.J.

    1996-06-01

    The objective of this paper is to perform an impact analysis of the Interim Storage Cask (ISC) of the Fast Flux Test Facility (FFTF) for a 4-ft end drop. The ISC is a concrete cask used to store spent nuclear fuels. The analysis is to justify the impact force calculated by General Atomics (General Atomics, 1994) using the ILMOD computer code. ILMOD determines the maximum force developed by the concrete crushing which occurs when the drop energy has been absorbed. The maximum force, multiplied by the dynamic load factor (DLF), was used to determine the maximum g-level on the cask during a 4-ft end drop accident onto the heavily reinforced FFTF Reactor Service Building`s concrete surface. For the analysis, this surface was assumed to be unyielding and the cask absorbed all the drop energy. This conservative assumption simplified the modeling used to qualify the cask`s structural integrity for this accident condition.

  13. Estimating the maximum potential revenue for grid connected electricity storage : arbitrage and regulation.

    SciTech Connect (OSTI)

    Byrne, Raymond Harry; Silva Monroy, Cesar Augusto.

    2012-12-01

    The valuation of an electricity storage device is based on the expected future cash ow generated by the device. Two potential sources of income for an electricity storage system are energy arbitrage and participation in the frequency regulation market. Energy arbitrage refers to purchasing (stor- ing) energy when electricity prices are low, and selling (discharging) energy when electricity prices are high. Frequency regulation is an ancillary service geared towards maintaining system frequency, and is typically procured by the independent system operator in some type of market. This paper outlines the calculations required to estimate the maximum potential revenue from participating in these two activities. First, a mathematical model is presented for the state of charge as a function of the storage device parameters and the quantities of electricity purchased/sold as well as the quantities o ered into the regulation market. Using this mathematical model, we present a linear programming optimization approach to calculating the maximum potential revenue from an elec- tricity storage device. The calculation of the maximum potential revenue is critical in developing an upper bound on the value of storage, as a benchmark for evaluating potential trading strate- gies, and a tool for capital nance risk assessment. Then, we use historical California Independent System Operator (CAISO) data from 2010-2011 to evaluate the maximum potential revenue from the Tehachapi wind energy storage project, an American Recovery and Reinvestment Act of 2009 (ARRA) energy storage demonstration project. We investigate the maximum potential revenue from two di erent scenarios: arbitrage only and arbitrage combined with the regulation market. Our analysis shows that participation in the regulation market produces four times the revenue compared to arbitrage in the CAISO market using 2010 and 2011 data. Then we evaluate several trading strategies to illustrate how they compare to the maximum

  14. "Table A52. Nonswitchable Minimum Requirements and Maximum Consumption"

    U.S. Energy Information Administration (EIA) Indexed Site

    2. Nonswitchable Minimum Requirements and Maximum Consumption" " Potential by Census Region, 1991" " (Estimates in Physical Units)" ,,,,"RSE" ,"Actual","Minimum","Maximum","Row" "Type of Energy","Consumption","Consumption(a)","Consumption(b)","Factors" "RSE Column Factors:",1,1.2,0.8 ," Total United States" ,"-","-","-"

  15. Extraordinary luminous soft X-ray transient MAXI J0158744 as an ignition of a nova on a very massive O-Ne white dwarf

    SciTech Connect (OSTI)

    Morii, M.; Serino, M.; Mihara, T.; Sugizaki, M.; Tomida, H.; Kimura, M.; Nakahira, S.; Suwa, F.; Negoro, H.; Kennea, J. A.; Pritchard, T.; Page, K. L.; Osborne, J. P.; Curran, P. A.; Walter, F. M.; Kuin, N. P. M.; Hiroi, K.; Usui, R.; Kawai, N.; Gehrels, N.; and others

    2013-12-20

    We present the observation of an extraordinary luminous soft X-ray transient, MAXI J0158744, by the Monitor of All-sky X-ray Image (MAXI) on 2011 November 11. This transient is characterized by a soft X-ray spectrum, a short duration (1.3 10{sup 3} s < ?T{sub d} < 1.10 10{sup 4} s), a rapid rise (<5.5 10{sup 3} s), and a huge peak luminosity of 2 10{sup 40} erg s{sup 1} in 0.7-7.0 keV band. With Swift observations and optical spectroscopy from the Small and Moderate Aperture Research Telescope System, we confirmed that the transient is a nova explosion, on a white dwarf in a binary with a Be star, located near the Small Magellanic Cloud. An early turn-on of the super-soft X-ray source (SSS) phase (<0.44 days), the short SSS phase duration of about one month, and a 0.92 keV neon emission line found in the third MAXI scan, 1296 s after the first detection, suggest that the explosion involves a small amount of ejecta and is produced on an unusually massive O-Ne white dwarf close to, or possibly over, the Chandrasekhar limit. We propose that the huge luminosity detected with MAXI was due to the fireball phase, a direct manifestation of the ignition of the thermonuclear runaway process in a nova explosion.

  16. Direct Aqueous-Phase Synthesis of Sub-10 nm “Luminous Pearls” with Enhanced in Vivo Renewable Near-Infrared Persistent Luminescence

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Li, Zhanjun; Zhang, Yuanwei; Wu, Xiang; Huang, Ling; Li, Dongsheng; Fan, Wei; Han, Gang

    2015-04-02

    Near-infrared (NIR) persistent luminescence nanoparticles (PLNPs), possessing unique NIR PL properties, have recently emerged as important materials for a wide variety of applications in chemistry and biology, for which they must endure high-temperature solid-state annealing reactions and subsequent complicated physical post-treatments. Herein, we report on a first direct aqueous-phase chemical synthesis route to NIR PLNPs and present their enhanced in vivo renewable NIR PL. Our method leads to monodisperse PLNPs as small as ca. 8 nm. Such sub-10 nm nanocrystals are readily dispersed and functionalized, and can form stable colloidal solutions in aqueous solution and cell culture medium for biologicalmore » applications. Under biotissue-penetrable red-light excitation, we found that such nanocrystals possess superior renewable PL photoluminescence in vitro and in vivo compared to their larger counterparts currently made by existing methods. In conclusion, we believe that this solid-state-reaction-free chemical approach overcomes the current key roadblock in regard to PLNP development, and thus will pave the way to broad use of these advanced miniature “luminous pearls” in photonics and biophotonics.« less

  17. On the Stochastic Maximum Principle in Optimal Control of Degenerate Diffusions with Lipschitz Coefficients

    SciTech Connect (OSTI)

    Bahlali, Khaled Djehiche, Boualem Mezerdi, Brahim

    2007-12-15

    We establish a stochastic maximum principle in optimal control of a general class of degenerate diffusion processes with global Lipschitz coefficients, generalizing the existing results on stochastic control of diffusion processes. We use distributional derivatives of the coefficients and the Bouleau Hirsh flow property, in order to define the adjoint process on an extension of the initial probability space.

  18. SALTSTONE DISPOSAL FACILITY: DETERMINATION OF THE PROBABLE MAXIMUM WATER TABLE ELEVATION

    SciTech Connect (OSTI)

    Hiergesell, R

    2005-04-01

    A coverage depicting the configuration of the probable maximum water table elevation in the vicinity of the Saltstone Disposal Facility (SDF) was developed to support the Saltstone program. This coverage is needed to support the construction of saltstone vaults to assure that they remain above the maximum elevation of the water table during the Performance Assessment (PA) period of compliance. A previous investigation to calculate the historical high water table beneath the SDF (Cook, 1983) was built upon to incorporate new data that has since become available to refine that estimate and develop a coverage that could be extended to the perennial streams adjacent to the SDF. This investigation incorporated the method used in the Cook, 1983 report to develop an estimate of the probable maximum water table for a group of wells that either existed at one time at or near the SDF or which currently exist. Estimates of the probable maximum water table at these wells were used to construct 2D contour lines depicting this surface beneath the SDF and extend them to the nearby hydrologic boundaries at the perennial streams adjacent to the SDF. Although certain measures were implemented to assure that the contour lines depict a surface above which the water table will not rise, the exact elevation of this surface cannot be known with complete certainty. It is therefore recommended that the construction of saltstone vaults incorporate a vertical buffer of at least 5-feet between the base of the vaults and the depicted probable maximum water table elevation. This should provide assurance that the water table under the wet extreme climatic condition will never rise to intercept the base of a vault.

  19. Enhancement of maximum attainable ion energy in the radiation pressure acceleration regime using a guiding structure

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Bulanov, S. S.; Esarey, E.; Schroeder, C. B.; Bulanov, S. V.; Esirkepov, T. Zh.; Kando, M.; Pegoraro, F.; Leemans, W. P.

    2015-03-13

    Radiation Pressure Acceleration is a highly efficient mechanism of laser driven ion acceleration, with the laser energy almost totally transferrable to the ions in the relativistic regime. There is a fundamental limit on the maximum attainable ion energy, which is determined by the group velocity of the laser. In the case of a tightly focused laser pulses, which are utilized to get the highest intensity, another factor limiting the maximum ion energy comes into play, the transverse expansion of the target. Transverse expansion makes the target transparent for radiation, thus reducing the effectiveness of acceleration. Utilization of an external guidingmore » structure for the accelerating laser pulse may provide a way of compensating for the group velocity and transverse expansion effects.« less

  20. Enhancement of maximum attainable ion energy in the radiation pressure acceleration regime using a guiding structure

    SciTech Connect (OSTI)

    Bulanov, S. S.; Esarey, E.; Schroeder, C. B.; Bulanov, S. V.; Esirkepov, T. Zh.; Kando, M.; Pegoraro, F.; Leemans, W. P.

    2015-03-13

    Radiation Pressure Acceleration is a highly efficient mechanism of laser driven ion acceleration, with the laser energy almost totally transferrable to the ions in the relativistic regime. There is a fundamental limit on the maximum attainable ion energy, which is determined by the group velocity of the laser. In the case of a tightly focused laser pulses, which are utilized to get the highest intensity, another factor limiting the maximum ion energy comes into play, the transverse expansion of the target. Transverse expansion makes the target transparent for radiation, thus reducing the effectiveness of acceleration. Utilization of an external guiding structure for the accelerating laser pulse may provide a way of compensating for the group velocity and transverse expansion effects.

  1. Evaluation of Maximum Radionuclide Groundwater Concentrations for Basement Fill Model. Zion Station Restoration Project

    SciTech Connect (OSTI)

    Sullivan, Terry

    2014-12-02

    ZionSolutions is in the process of decommissioning the Zion Nuclear Power Plant in order to establish a new water treatment plant. There is some residual radioactive particles from the plant which need to be brought down to levels so an individual who receives water from the new treatment plant does not receive a radioactive dose in excess of 25 mrem/y⁻¹. The objectives of this report are: (a) To present a simplified conceptual model for release from the buildings with residual subsurface structures that can be used to provide an upper bound on contaminant concentrations in the fill material; (b) Provide maximum water concentrations and the corresponding amount of mass sorbed to the solid fill material that could occur in each building for use in dose assessment calculations; (c) Estimate the maximum concentration in a well located outside of the fill material; and (d) Perform a sensitivity analysis of key parameters.

  2. U.S. Lower 48 States Onshore Maximum Number of Active Crews Engaged in

    Gasoline and Diesel Fuel Update (EIA)

    Seismic Surveying (Number of Elements) Onshore Maximum Number of Active Crews Engaged in Seismic Surveying (Number of Elements) U.S. Lower 48 States Onshore Maximum Number of Active Crews Engaged in Seismic Surveying (Number of Elements) Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2000 0 0 41 41 38 43 44 45 43 46 46 48 2001 44 45 45 47 45 42 42 41 39 39 42 41 2002 38 40 35 32 32 32 34 33 37 38 35 31 2003 28 29 28 27 24 25 28 30 30 31 31 32 2004 33 35 35 36 35 39 38 39 40 42 42 41

  3. U.S. Maximum Number of Active Crews Engaged in Seismic Surveying (Number of

    Gasoline and Diesel Fuel Update (EIA)

    Elements) Maximum Number of Active Crews Engaged in Seismic Surveying (Number of Elements) U.S. Maximum Number of Active Crews Engaged in Seismic Surveying (Number of Elements) Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2000 0 0 62 63 59 63 58 61 59 63 62 65 2001 61 61 63 65 64 60 58 56 54 58 59 58 2002 54 57 54 50 51 50 52 50 56 57 50 43 2003 40 41 41 40 38 39 41 43 39 39 38 42 2004 43 45 45 45 44 49 48 49 48 48 49 50 2005 52 53 51 50 55 57 54 55 56 57 57 58 2006 55 57 59 58 58 57

  4. Dynamic Programming and Error Estimates for Stochastic Control Problems with Maximum Cost

    SciTech Connect (OSTI)

    Bokanowski, Olivier; Picarelli, Athena; Zidani, Hasnaa

    2015-02-15

    This work is concerned with stochastic optimal control for a running maximum cost. A direct approach based on dynamic programming techniques is studied leading to the characterization of the value function as the unique viscosity solution of a second order Hamilton–Jacobi–Bellman (HJB) equation with an oblique derivative boundary condition. A general numerical scheme is proposed and a convergence result is provided. Error estimates are obtained for the semi-Lagrangian scheme. These results can apply to the case of lookback options in finance. Moreover, optimal control problems with maximum cost arise in the characterization of the reachable sets for a system of controlled stochastic differential equations. Some numerical simulations on examples of reachable analysis are included to illustrate our approach.

  5. Three dimensional winds: A maximum cross-correlation application to elastic lidar data

    SciTech Connect (OSTI)

    Buttler, W.T.

    1996-05-01

    Maximum cross-correlation techniques have been used with satellite data to estimate winds and sea surface velocities for several years. Los Alamos National Laboratory (LANL) is currently using a variation of the basic maximum cross-correlation technique, coupled with a deterministic application of a vector median filter, to measure transverse winds as a function of range and altitude from incoherent elastic backscatter lidar (light detection and ranging) data taken throughout large volumes within the atmospheric boundary layer. Hourly representations of three-dimensional wind fields, derived from elastic lidar data taken during an air-quality study performed in a region of complex terrain near Sunland Park, New Mexico, are presented and compared with results from an Environmental Protection Agency (EPA) approved laser doppler velocimeter. The wind fields showed persistent large scale eddies as well as general terrain-following winds in the Rio Grande valley.

  6. Direct tests of micro channel plates as the active element of a new shower maximum detector

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Ronzhin, A.; Los, S.; Ramberg, E.; Apresyan, A.; Xie, S.; Spiropulu, M.; Kim, H.

    2015-05-22

    We continue the study of micro channel plates (MCP) as the active element of a shower maximum (SM) detector. We present below test beam results obtained with MCPs detecting directly secondary particles of an electromagnetic shower. The MCP efficiency to shower particles is close to 100%. In conclusion, the time resolution obtained for this new type of the SM detector is at the level of 40 ps.

  7. Alaska Maximum Number of Active Crews Engaged in Seismic Surveying (Number

    Gasoline and Diesel Fuel Update (EIA)

    of Elements) Seismic Surveying (Number of Elements) Alaska Maximum Number of Active Crews Engaged in Seismic Surveying (Number of Elements) Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2000 0 0 2 3 3 3 1 1 0 0 0 0 2001 0 0 0 0 2 2 0 0 0 0 0 0 2002 2 2 2 2 2 2 2 2 2 2 2 1 2003 0 0 2 2 2 2 2 2

  8. A new look at maximum and minimum temperature trends for the globe

    SciTech Connect (OSTI)

    Easterling, D.R.; Peterson, T.C.; Karl, T.R.

    1997-11-01

    A number of recent studies have established that differential changes in daily maximum and minimum temperatures are occurring, resulting in changes in the diurnal temperature range (DTR) for many parts of the globe. Large-scale trends in the USA indicate that minimum temperatures are increasing at a faster rate than maximum temperatures, resulting in a narrowing in the DTR. This paper updates and extends the analysis of changes in the DTR in three ways: (1) by increasing the areal coverage to more than half the global landmass, (2) by addressing the issue of homogeneity of the data, and (3) by examining the potential effects of urban stations on the calculated trends. The update includes data for an additional 15% of the global land area and an extension of the analysis period used in a previous study. Homogeneity techniques were used on the data to adjust individual station data for undocumented discontinuities. Annual maximum and minimum temperature and DTR time series for the 1950-1993 period averaged over 54% of the total global land area are presented. The trend for the maximum temperature is 0.88 C/100 years, which is consistent with earlier findings. However, the trend for the minimum temperature is 1.86 C/100 years; this is less than found in previous analyses and leads to a smaller trend in the DTR. This finding is not surprising since much of the data added in this study are for tropical and sub-tropical regions where temperature trends are not expected to be as large as in higher latitude regions. The effect of urbanization on the global trends is found to be on the order of 0.1 C/100 years or less, which is consistent with previous investigations. 14 refs., 2 figs.

  9. Direct tests of micro channel plates as the active element of a new shower maximum detector

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Ronzhin, A.; Los, S.; Ramberg, E.; Apresyan, A.; Xie, S.; Spiropulu, M.; Kim, H.

    2015-05-22

    We continue the study of micro channel plates (MCP) as the active element of a shower maximum (SM) detector. We present below test beam results obtained with MCPs detecting directly secondary particles of an electromagnetic shower. The MCP efficiency to shower particles is close to 100%. Furthermore, the time resolution obtained for this new type of the SM detector is at the level of 40 ps.

  10. Hydrodynamic equations for electrons in graphene obtained from the maximum entropy principle

    SciTech Connect (OSTI)

    Barletti, Luigi

    2014-08-15

    The maximum entropy principle is applied to the formal derivation of isothermal, Euler-like equations for semiclassical fermions (electrons and holes) in graphene. After proving general mathematical properties of the equations so obtained, their asymptotic form corresponding to significant physical regimes is investigated. In particular, the diffusive regime, the Maxwell-Boltzmann regime (high temperature), the collimation regime and the degenerate gas limit (vanishing temperature) are considered.

  11. BONA FIDE, STRONG-VARIABLE GALACTIC LUMINOUS BLUE VARIABLE STARS ARE FAST ROTATORS: DETECTION OF A HIGH ROTATIONAL VELOCITY IN HR CARINAE

    SciTech Connect (OSTI)

    Groh, J. H.; Damineli, A.; Moises, A. P.; Teodoro, M.; Hillier, D. J.; Barba, R.; Fernandez-Lajus, E.; Gamen, R. C.; Solivella, G.

    2009-11-01

    We report optical observations of the luminous blue variable (LBV) HR Carinae which show that the star has reached a visual minimum phase in 2009. More importantly, we detected absorptions due to Si IV lambdalambda4088-4116. To match their observed line profiles from 2009 May, a high rotational velocity of v{sub rot} approx = 150 +- 20 km s{sup -1} is needed (assuming an inclination angle of 30 deg.), implying that HR Car rotates at approx =0.88 +- 0.2 of its critical velocity for breakup (v{sub crit}). Our results suggest that fast rotation is typical in all strong-variable, bona fide galactic LBVs, which present S-Dor-type variability. Strong-variable LBVs are located in a well-defined region of the HR diagram during visual minimum (the 'LBV minimum instability strip'). We suggest this region corresponds to where v{sub crit} is reached. To the left of this strip, a forbidden zone with v{sub rot}/v{sub crit}>1 is present, explaining why no LBVs are detected in this zone. Since dormant/ex LBVs like P Cygni and HD 168625 have low v{sub rot}, we propose that LBVs can be separated into two groups: fast-rotating, strong-variable stars showing S-Dor cycles (such as AG Car and HR Car) and slow-rotating stars with much less variability (such as P Cygni and HD 168625). We speculate that supernova (SN) progenitors which had S-Dor cycles before exploding (such as in SN 2001ig, SN 2003bg, and SN 2005gj) could have been fast rotators. We suggest that the potential difficulty of fast-rotating Galactic LBVs to lose angular momentum is additional evidence that such stars could explode during the LBV phase.

  12. LACERTA I AND CASSIOPEIA III. TWO LUMINOUS AND DISTANT ANDROMEDA SATELLITE DWARF GALAXIES FOUND IN THE 3{pi} PAN-STARRS1 SURVEY

    SciTech Connect (OSTI)

    Martin, Nicolas F.; Laevens, Benjamin P. M.; Slater, Colin T.; Bell, Eric F.; Schlafly, Edward F.; Morganson, Eric; Rix, Hans-Walter; Bernard, Edouard J.; Ferguson, Annette M. N.; Finkbeiner, Douglas P.; Burgett, William S.; Chambers, Kenneth C.; Hodapp, Klaus W.; Kaiser, Nicholas; Kudritzki, Rolf-Peter; Magnier, Eugene A.; Morgan, Jeffrey S.; Tonry, John L.; Wainscoat, Richard J.; Price, Paul A.

    2013-07-20

    We report the discovery of two new dwarf galaxies, Lacerta I/Andromeda XXXI (Lac I/And XXXI) and Cassiopeia III/Andromeda XXXII (Cas III/And XXXII), in stacked Pan-STARRS1 r{sub P1}- and i{sub P1}-band imaging data. Both are luminous systems (M{sub V} {approx} -12) located at projected distances of 20. Degree-Sign 3 and 10. Degree-Sign 5 from M31. Lac I and Cas III are likely satellites of the Andromeda galaxy with heliocentric distances of 756{sup +44}{sub -28} kpc and 772{sup +61}{sub -56} kpc, respectively, and corresponding M31-centric distances of 275 {+-} 7 kpc and 144{sup +6}{sub -4} kpc. The brightest of recent Local Group member discoveries, these two new dwarf galaxies owe their late discovery to their large sizes (r{sub h} = 4.2{sup +0.4}{sub -0.5} arcmin or 912{sup +124}{sub -93} pc for Lac I; r{sub h} = 6.5{sup +1.2}{sub -1.0} arcmin or 1456 {+-} 267 pc for Cas III) and consequently low surface brightness ({mu}{sub 0} {approx} 26.0 mag arcsec{sup -2}), as well as to the lack of a systematic survey of regions at large radii from M31, close to the Galactic plane. This latter limitation is now alleviated by the 3{pi} Pan-STARRS1 survey, which could lead to the discovery of other distant Andromeda satellite dwarf galaxies.

  13. On Parallel Push-Relabel based Algorithms for Bipartite Maximum Matching

    SciTech Connect (OSTI)

    Langguth, Johannes; Azad, Md Ariful; Halappanavar, Mahantesh; Manne, Fredrik

    2014-07-01

    We study multithreaded push-relabel based algorithms for computing maximum cardinality matching in bipartite graphs. Matching is a fundamental combinatorial (graph) problem with applications in a wide variety of problems in science and engineering. We are motivated by its use in the context of sparse linear solvers for computing maximum transversal of a matrix. We implement and test our algorithms on several multi-socket multicore systems and compare their performance to state-of-the-art augmenting path-based serial and parallel algorithms using a testset comprised of a wide range of real-world instances. Building on several heuristics for enhancing performance, we demonstrate good scaling for the parallel push-relabel algorithm. We show that it is comparable to the best augmenting path-based algorithms for bipartite matching. To the best of our knowledge, this is the first extensive study of multithreaded push-relabel based algorithms. In addition to a direct impact on the applications using matching, the proposed algorithmic techniques can be extended to preflow-push based algorithms for computing maximum flow in graphs.

  14. Efficacy of 45 lm/W Achieved in White OLED

    Broader source: Energy.gov [DOE]

    Universal Display Corporation (UDC) successfully demonstrated an all phosphorescent white organic light emitting diode (WOLED™) with a power efficacy of 45 lm/W at 1,000 cd/m2. This high-efficacy device was enabled by lowering the device operating voltage, increasing the outcoupling efficiency to ~40% from ~20%, and by incorporating highly efficient phosphorescent emitters that are capable of converting nearly all current passing through a WOLED into light.

  15. Cree Sets New Benchmarks for LED Efficacy and Brightness

    Broader source: Energy.gov [DOE]

    Cree has successfully created a cool white LED prototype that delivers 107 lm/W at 350mA. This achievement builds on the Cree EZBright® LED chip platform, developed in part with prior funding support from DOE. Cree made the prototype LED under their DOE project focused on developing LED chips incorporating photonic crystal elements for improved light extraction and novel package technology for higher down-conversion efficiency compared to conventional LEDs. Based on a 1 millimeter-square chip, the new prototype LED produces white light with a CCT of 5500K and a CRI of 73. Integration of four of these prototype LEDs can produce luminous flux of more than 450 lumens.

  16. Luminate LLC | Open Energy Information

    Open Energy Info (EERE)

    to companies active in the energy industry. They have specialist expertises in the biofuel industry. Coordinates: 39.74001, -104.992259 Show Map Loading map......

  17. Free kick instead of cross-validation in maximum-likelihood refinement of macromolecular crystal structures

    SciTech Connect (OSTI)

    Pranikar, Jure [Institute Joef Stefan, Jamova 39, 1000 Ljubljana (Slovenia); University of Primorska, (Slovenia); Turk, Duan, E-mail: dusan.turk@ijs.si [Institute Joef Stefan, Jamova 39, 1000 Ljubljana (Slovenia); Center of Excellence for Integrated Approaches in Chemistry and Biology of Proteins, (Slovenia)

    2014-12-01

    The maximum-likelihood free-kick target, which calculates model error estimates from the work set and a randomly displaced model, proved superior in the accuracy and consistency of refinement of crystal structures compared with the maximum-likelihood cross-validation target, which calculates error estimates from the test set and the unperturbed model. The refinement of a molecular model is a computational procedure by which the atomic model is fitted to the diffraction data. The commonly used target in the refinement of macromolecular structures is the maximum-likelihood (ML) function, which relies on the assessment of model errors. The current ML functions rely on cross-validation. They utilize phase-error estimates that are calculated from a small fraction of diffraction data, called the test set, that are not used to fit the model. An approach has been developed that uses the work set to calculate the phase-error estimates in the ML refinement from simulating the model errors via the random displacement of atomic coordinates. It is called ML free-kick refinement as it uses the ML formulation of the target function and is based on the idea of freeing the model from the model bias imposed by the chemical energy restraints used in refinement. This approach for the calculation of error estimates is superior to the cross-validation approach: it reduces the phase error and increases the accuracy of molecular models, is more robust, provides clearer maps and may use a smaller portion of data for the test set for the calculation of R{sub free} or may leave it out completely.

  18. SPECTROPOLARIMETRY OF THE TYPE Ia SN 2007sr TWO MONTHS AFTER MAXIMUM LIGHT

    SciTech Connect (OSTI)

    Zelaya, P.; Quinn, J. R.; Clocchiatti, A.; Baade, D.; Patat, F.; Hoeflich, P.; Maund, J.; Wang, L.; Wheeler, J. C.

    2013-02-01

    We present late-time spectropolarimetric observations of SN 2007sr, obtained with the Very Large Telescope at the ESO Paranal Observatory when the object was 63 days after maximum light. The late-time spectrum displays strong line polarization in the Ca II absorption features. SN 2007sr adds to the case of some normal Type Ia supernovae that show high line polarization or repolarization at late times, a fact that might be connected with the presence of high-velocity features at early times.

  19. A New Maximum-Likelihood Change Estimator for Two-Pass SAR Coherent Change Detection.

    SciTech Connect (OSTI)

    Wahl, Daniel E.; Yocky, David A.; Jakowatz, Charles V,

    2014-09-01

    In this paper, we derive a new optimal change metric to be used in synthetic aperture RADAR (SAR) coherent change detection (CCD). Previous CCD methods tend to produce false alarm states (showing change when there is none) in areas of the image that have a low clutter-to-noise power ratio (CNR). The new estimator does not suffer from this shortcoming. It is a surprisingly simple expression, easy to implement, and is optimal in the maximum-likelihood (ML) sense. The estimator produces very impressive results on the CCD collects that we have tested.

  20. A HIGH SPATIAL RESOLUTION MID-INFRARED SPECTROSCOPIC STUDY OF THE NUCLEI AND STAR-FORMING REGIONS IN LUMINOUS INFRARED GALAXIES

    SciTech Connect (OSTI)

    Diaz-Santos, Tanio; Alonso-Herrero, Almudena; Colina, Luis; Pereira-Santaella, Miguel; Packham, Christopher; Telesco, Charles M.; Levenson, N. A.; Roche, Patrick F.

    2010-03-01

    We present a high spatial (diffraction-limited) resolution ({approx}0.''3) mid-infrared (MIR) spectroscopic study of the nuclei and star-forming regions of four local luminous infrared galaxies (LIRGs) using T-ReCS on the Gemini South telescope. We investigate the spatial variations of the features seen in the N-band spectra of LIRGs on scales of {approx}100 pc, which allow us to resolve their nuclear regions and separate the active galactic nucleus (AGN) emission from that of the star formation (SF). We compare (qualitatively and quantitatively) our Gemini T-ReCS nuclear and integrated spectra of LIRGs with those obtained with Spitzer IRS. Star-forming regions and AGNs show distinct features in the MIR spectra, and we spatially separate these, which is not possible using the Spitzer data. The 9.7 {mu}m silicate absorption feature is weaker in the nuclei of the LIRGs than in the surrounding regions. This is probably due to the either clumpy or compact environment of the central AGN or young, nuclear starburst. We find that the [Ne II]12.81 {mu}m luminosity surface density is tightly and directly correlated with that of Paalpha for the LIRG star-forming regions (slope of 1.00 +- 0.02). Although the 11.3 {mu}m PAH feature shows also a trend with Paalpha, this is not common for all the regions and the slope is significantly lower. We also find that the [Ne II]12.81 {mu}m/Paalpha ratio does not depend on the Paalpha equivalent width (EW), i.e., on the age of the ionizing stellar populations, suggesting that, on the scales probed here, the [Ne II]12.81 {mu}m emission line is a good tracer of the SF activity in LIRGs. On the other hand, the 11.3 {mu}m PAH/Paalpha ratio increases for smaller values of the Paalpha EW (increasing ages), indicating that the 11.3 {mu}m PAH feature can also be excited by older stars than those responsible for the Paalpha emission. Finally, more data are needed in order to address the different physical processes (age of the stellar populations

  1. Maximum-likelihood fitting of data dominated by Poisson statistical uncertainties

    SciTech Connect (OSTI)

    Stoneking, M.R.; Den Hartog, D.J.

    1996-06-01

    The fitting of data by {chi}{sup 2}-minimization is valid only when the uncertainties in the data are normally distributed. When analyzing spectroscopic or particle counting data at very low signal level (e.g., a Thomson scattering diagnostic), the uncertainties are distributed with a Poisson distribution. The authors have developed a maximum-likelihood method for fitting data that correctly treats the Poisson statistical character of the uncertainties. This method maximizes the total probability that the observed data are drawn from the assumed fit function using the Poisson probability function to determine the probability for each data point. The algorithm also returns uncertainty estimates for the fit parameters. They compare this method with a {chi}{sup 2}-minimization routine applied to both simulated and real data. Differences in the returned fits are greater at low signal level (less than {approximately}20 counts per measurement). the maximum-likelihood method is found to be more accurate and robust, returning a narrower distribution of values for the fit parameters with fewer outliers.

  2. Analysis to determine the maximum dimensions of flexible apertures in sensored security netting products.

    SciTech Connect (OSTI)

    Murton, Mark; Bouchier, Francis A.; vanDongen, Dale T.; Mack, Thomas Kimball; Cutler, Robert Paul; Ross, Michael P.

    2013-08-01

    Although technological advances provide new capabilities to increase the robustness of security systems, they also potentially introduce new vulnerabilities. New capability sometimes requires new performance requirements. This paper outlines an approach to establishing a key performance requirement for an emerging intrusion detection sensor: the sensored net. Throughout the security industry, the commonly adopted standard for maximum opening size through barriers is a requirement based on square inches-typically 96 square inches. Unlike standard rigid opening, the dimensions of a flexible aperture are not fixed, but variable and conformable. It is demonstrably simple for a human intruder to move through a 96-square-inch opening that is conformable to the human body. The longstanding 96-square-inch requirement itself, though firmly embedded in policy and best practice, lacks a documented empirical basis. This analysis concluded that the traditional 96-square-inch standard for openings is insufficient for flexible openings that are conformable to the human body. Instead, a circumference standard is recommended for these newer types of sensored barriers. The recommended maximum circumference for a flexible opening should be no more than 26 inches, as measured on the inside of the netting material.

  3. Estimates of maximum strains induced in buried pipelines by dynamic loading

    SciTech Connect (OSTI)

    Fernandez, G.; Al-Chaar, G.; Brady, P.

    1995-12-31

    An evaluation of pipe strains measured during full scale blast in-situ tests was carried out to assess the effects produced by a nearby quarry blast in a buried, steel pipeline carrying pressurized gas. The result of the blast tests indicated that the magnitude of the maximum circumferential strain is equal or larger than the magnitude of the maximum axial strain measured in the pipe. It was also observed that circumferential strains can develop simultaneously with the dynamic-induced axial strains, resulting in a more critical loading condition than the one contemplated by the ASCE (1983) design guidelines for seismic loading. This behavior can become critical in pressurized pipes where significant circumferential stresses are already present under normal operating conditions. Based on the results of these tests, recommendations for including circumferential strains are suggested to the ASCE (1983) Design Guidelines. Consideration should be given to a compressive wave traveling at a high angle which respect to the longitudinal axis of the pipe which can induce squeezing or ovaling of the pipe section, resulting in significant circumferential strains in the pipe.

  4. Dithering Digital Ripple Correlation Control for Photovoltaic Maximum Power Point Tracking

    SciTech Connect (OSTI)

    Barth, C; Pilawa-Podgurski, RCN

    2015-08-01

    This study demonstrates a new method for rapid and precise maximum power point tracking in photovoltaic (PV) applications using dithered PWM control. Constraints imposed by efficiency, cost, and component size limit the available PWM resolution of a power converter, and may in turn limit the MPP tracking efficiency of the PV system. In these scenarios, PWM dithering can be used to improve average PWM resolution. In this study, we present a control technique that uses ripple correlation control (RCC) on the dithering ripple, thereby achieving simultaneous fast tracking speed and high tracking accuracy. Moreover, the proposed method solves some of the practical challenges that have to date limited the effectiveness of RCC in solar PV applications. We present a theoretical derivation of the principles behind dithering digital ripple correlation control, as well as experimental results that show excellent tracking speed and accuracy with basic hardware requirements.

  5. Maximum Achievable Control Technology for New Industrial Boilers (released in AEO2005)

    Reports and Publications (EIA)

    2005-01-01

    As part of Clean Air Act 90 (CAAA90, the EPA on February 26, 2004, issued a final rulethe National Emission Standards for Hazardous Air Pollutants (NESHAP) to reduce emissions of hazardous air pollutants (HAPs) from industrial, commercial, and institutional boilers and process heaters. The rule requires industrial boilers and process heaters to meet limits on HAP emissions to comply with a Maximum Achievable Control Technology (MACT) floor level of control that is the minimum level such sources must meet to comply with the rule. The major HAPs to be reduced are hydrochloric acid, hydrofluoric acid, arsenic, beryllium, cadmium, and nickel. The EPA predicts that the boiler MACT rule will reduce those HAP emissions from existing sources by about 59,000 tons per year in 2005.

  6. A 3D approximate maximum likelihood solver for localization of fish implanted with acoustic transmitters

    SciTech Connect (OSTI)

    Li, Xinya; Deng, Z. Daniel; USA, Richland Washington; Sun, Yannan; USA, Richland Washington; Martinez, Jayson J.; USA, Richland Washington; Fu, Tao; USA, Richland Washington; McMichael, Geoffrey A.; USA, Richland Washington; Carlson, Thomas J.; USA, Richland Washington

    2014-11-27

    Better understanding of fish behavior is vital for recovery of many endangered species including salmon. The Juvenile Salmon Acoustic Telemetry System (JSATS) was developed to observe the out-migratory behavior of juvenile salmonids tagged by surgical implantation of acoustic micro-transmitters and to estimate the survival when passing through dams on the Snake and Columbia Rivers. A robust three-dimensional solver was needed to accurately and efficiently estimate the time sequence of locations of fish tagged with JSATS acoustic transmitters, to describe in sufficient detail the information needed to assess the function of dam-passage design alternatives. An approximate maximum likelihood solver was developed using measurements of time difference of arrival from all hydrophones in receiving arrays on which a transmission was detected. Field experiments demonstrated that the developed solver performed significantly better in tracking efficiency and accuracy than other solvers described in the literature.

  7. A 3D approximate maximum likelihood solver for localization of fish implanted with acoustic transmitters

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Li, Xinya; Deng, Z. Daniel; USA, Richland Washington; Sun, Yannan; USA, Richland Washington; Martinez, Jayson J.; USA, Richland Washington; Fu, Tao; USA, Richland Washington; McMichael, Geoffrey A.; et al

    2014-11-27

    Better understanding of fish behavior is vital for recovery of many endangered species including salmon. The Juvenile Salmon Acoustic Telemetry System (JSATS) was developed to observe the out-migratory behavior of juvenile salmonids tagged by surgical implantation of acoustic micro-transmitters and to estimate the survival when passing through dams on the Snake and Columbia Rivers. A robust three-dimensional solver was needed to accurately and efficiently estimate the time sequence of locations of fish tagged with JSATS acoustic transmitters, to describe in sufficient detail the information needed to assess the function of dam-passage design alternatives. An approximate maximum likelihood solver was developedmore » using measurements of time difference of arrival from all hydrophones in receiving arrays on which a transmission was detected. Field experiments demonstrated that the developed solver performed significantly better in tracking efficiency and accuracy than other solvers described in the literature.« less

  8. A Distributed Approach to Maximum Power Point Tracking for Photovoltaic Submodule Differential Power Processing

    SciTech Connect (OSTI)

    Qin, SB; Cady, ST; Dominguez-Garcia, AD; Pilawa-Podgurski, RCN

    2015-04-01

    This paper presents the theory and implementation of a distributed algorithm for controlling differential power processing converters in photovoltaic (PV) applications. This distributed algorithm achieves true maximum power point tracking of series-connected PV submodules by relying only on local voltage measurements and neighbor-to-neighbor communication between the differential power converters. Compared to previous solutions, the proposed algorithm achieves reduced number of perturbations at each step and potentially faster tracking without adding extra hardware; all these features make this algorithm well-suited for long submodule strings. The formulation of the algorithm, discussion of its properties, as well as three case studies are presented. The performance of the distributed tracking algorithm has been verified via experiments, which yielded quantifiable improvements over other techniques that have been implemented in practice. Both simulations and hardware experiments have confirmed the effectiveness of the proposed distributed algorithm.

  9. A new maximum-likelihood change estimator for two-pass SAR coherent change detection

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Wahl, Daniel E.; Yocky, David A.; Jakowatz, Jr., Charles V.; Simonson, Katherine Mary

    2016-01-11

    In past research, two-pass repeat-geometry synthetic aperture radar (SAR) coherent change detection (CCD) predominantly utilized the sample degree of coherence as a measure of the temporal change occurring between two complex-valued image collects. Previous coherence-based CCD approaches tend to show temporal change when there is none in areas of the image that have a low clutter-to-noise power ratio. Instead of employing the sample coherence magnitude as a change metric, in this paper, we derive a new maximum-likelihood (ML) temporal change estimate—the complex reflectance change detection (CRCD) metric to be used for SAR coherent temporal change detection. The new CRCD estimatormore » is a surprisingly simple expression, easy to implement, and optimal in the ML sense. As a result, this new estimate produces improved results in the coherent pair collects that we have tested.« less

  10. U.S.Lower 48 States Offshore Maximum Number of Active Crews Engaged in

    Gasoline and Diesel Fuel Update (EIA)

    Three-Dimensional Seismic Surveying (Number of Elements) Three-Dimensional Seismic Surveying (Number of Elements) U.S.Lower 48 States Offshore Maximum Number of Active Crews Engaged in Three-Dimensional Seismic Surveying (Number of Elements) Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2000 0 0 11 11 11 9 6 7 8 9 8 8 2001 7 7 9 9 8 7 8 8 9 10 10 9 2002 6 6 7 7 8 7 8 7 7 7 5 4 2003 4 4 4 4 4 4 4 4 2 3 3 5 2004 5 5 5 4 4 4 4 4 2 2 4 4 2005 4 4 6 6 6 5 5 5 5 5 5 5 2006 5 6 6 6 6 5 5 5 5

  11. U.S.Lower 48 States Offshore Maximum Number of Active Crews Engaged in

    Gasoline and Diesel Fuel Update (EIA)

    Two-Dimensional Seismic Surveying (Number of Elements) Two-Dimensional Seismic Surveying (Number of Elements) U.S.Lower 48 States Offshore Maximum Number of Active Crews Engaged in Two-Dimensional Seismic Surveying (Number of Elements) Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2000 0 0 7 7 6 7 6 7 7 7 7 8 2001 9 8 9 9 9 9 8 7 6 9 7 8 2002 8 9 10 9 9 9 8 8 10 10 8 7 2003 8 8 7 7 8 8 7 7 7 5 4 5 2004 5 5 5 5 5 4 4 4 4 2 1 3 2005 5 5 6 6 7 7 6 6 6 6 6 6 2006 6 6 6 5 5 7 4 3 2 2 3 3

  12. U.S.Lower 48 States Onshore Maximum Number of Active Crews Engaged in

    Gasoline and Diesel Fuel Update (EIA)

    Four-Dimensional Seismic Surveying (Number of Elements) Four-Dimensional Seismic Surveying (Number of Elements) U.S.Lower 48 States Onshore Maximum Number of Active Crews Engaged in Four-Dimensional Seismic Surveying (Number of Elements) Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2000 0 0 1 1 1 1 1 1 1 1 1 1 2001 1 1 1 1 1 1 1 1 1 1 1 1 2002 0 0 0 0 0 0 0 0 0 0 0 0 2003 1 0 0 0 0 0 0 0 0 0 0 0 2004 0 0 0 0 0 0 0 0 0 0 0 0 2005 0 0 0 0 0 0 0 0 0 0 0 0 2006 0 0 0 0 0 0 0 0 0 0 0 0

  13. U.S.Lower 48 States Onshore Maximum Number of Active Crews Engaged in

    Gasoline and Diesel Fuel Update (EIA)

    Three-Dimensional Seismic Surveying (Number of Elements) Three-Dimensional Seismic Surveying (Number of Elements) U.S.Lower 48 States Onshore Maximum Number of Active Crews Engaged in Three-Dimensional Seismic Surveying (Number of Elements) Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2000 0 0 36 36 34 37 39 40 39 41 40 41 2001 38 38 38 39 37 35 35 32 30 33 34 33 2002 32 31 26 25 24 23 26 26 28 30 27 22 2003 19 20 20 20 17 18 21 22 22 24 24 25 2004 25 27 27 27 26 30 30 31 32 34 33 32

  14. U.S.Lower 48 States Onshore Maximum Number of Active Crews Engaged in

    Gasoline and Diesel Fuel Update (EIA)

    Two-Dimensional Seismic Surveying (Number of Elements) Two-Dimensional Seismic Surveying (Number of Elements) U.S.Lower 48 States Onshore Maximum Number of Active Crews Engaged in Two-Dimensional Seismic Surveying (Number of Elements) Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2000 0 0 4 4 3 5 4 4 3 4 4 5 2001 5 6 6 7 7 6 6 8 8 5 7 7 2002 6 9 9 7 8 9 8 7 9 8 8 8 2003 8 9 8 7 7 7 7 8 8 7 7 7 2004 8 8 8 9 9 9 8 8 8 8 9 9 2005 8 8 6 8 8 9 8 8 7 6 5 6 2006 5 5 4 4 4 9 5 4 4 5 5 5 2007

  15. Online Robot Dead Reckoning Localization Using Maximum Relative Entropy Optimization With Model Constraints

    SciTech Connect (OSTI)

    Urniezius, Renaldas

    2011-03-14

    The principle of Maximum relative Entropy optimization was analyzed for dead reckoning localization of a rigid body when observation data of two attached accelerometers was collected. Model constraints were derived from the relationships between the sensors. The experiment's results confirmed that accelerometers each axis' noise can be successfully filtered utilizing dependency between channels and the dependency between time series data. Dependency between channels was used for a priori calculation, and a posteriori distribution was derived utilizing dependency between time series data. There was revisited data of autocalibration experiment by removing the initial assumption that instantaneous rotation axis of a rigid body was known. Performance results confirmed that such an approach could be used for online dead reckoning localization.

  16. Application of Markov chain model to daily maximum temperature for thermal comfort in Malaysia

    SciTech Connect (OSTI)

    Nordin, Muhamad Asyraf bin Che; Hassan, Husna

    2015-10-22

    The Markov chain’s first order principle has been widely used to model various meteorological fields, for prediction purposes. In this study, a 14-year (2000-2013) data of daily maximum temperatures in Bayan Lepas were used. Earlier studies showed that the outdoor thermal comfort range based on physiologically equivalent temperature (PET) index in Malaysia is less than 34°C, thus the data obtained were classified into two state: normal state (within thermal comfort range) and hot state (above thermal comfort range). The long-run results show the probability of daily temperature exceed TCR will be only 2.2%. On the other hand, the probability daily temperature within TCR will be 97.8%.

  17. Phosphors for near UV-Emitting LED's for Efficacious Generation of White Light

    SciTech Connect (OSTI)

    McKittrick, Joanna

    2013-09-30

    1) We studied phosphors for near-UV (nUV) LED application as an alternative to blue LEDs currently being used in SSL systems. We have shown that nUV light sources could be very efficient at high current and will have significantly less binning at both the chip and phosphor levels. We identified phosphor blends that could yield 4100K lamps with a CRI of approximately 80 and LPWnUV,opt equal to 179 for the best performing phosphor blend. Considering the fact that the lamps were not optimized for light coupling, the results are quite impressive. The main bottleneck is an optimum blue phosphor with a peak near 440 nm with a full width half maximum of about 25 nm and a quantum efficiency of >95%. Unfortunately, that may be a very difficult task when we want to excite a phosphor at ~400 nm with a very small margin for Stokes shift. Another way is to have all the phosphors in the blend having the excitation peak at 400 nm or slightly shorter wavelength. This could lead to a white light source with no body color and optimum efficacy due to no self-absorption effects by phosphors in the blend. This is even harder than finding an ideal blue phosphor, but not necessarily impossible. 2) With the phosphor blends identified, light sources using nUV LEDs at high current could be designed with comparable efficacy to those using blue LEDs. It will allow us to design light sources with multiple wattages using the same chips and phosphor blends simply by varying the input current. In the case of blue LEDs, this is not currently possible because varying the current will lower the efficacy at high current and alter the color point. With improvement of phosphor blends, control over CRI could improve. Less binning at the chip level and also at the phosphor blend level could reduce the cost of SSL light sources. 3) This study provided a deeper understanding of phosphor characteristics needed for LEDs in general and nUV LEDs in particular. Two students received Ph.D. degrees and three

  18. Weakest solar wind of the space age and the current 'MINI' solar maximum

    SciTech Connect (OSTI)

    McComas, D. J.; Angold, N.; Elliott, H. A.; Livadiotis, G.; Schwadron, N. A.; Smith, C. W.; Skoug, R. M.

    2013-12-10

    The last solar minimum, which extended into 2009, was especially deep and prolonged. Since then, sunspot activity has gone through a very small peak while the heliospheric current sheet achieved large tilt angles similar to prior solar maxima. The solar wind fluid properties and interplanetary magnetic field (IMF) have declined through the prolonged solar minimum and continued to be low through the current mini solar maximum. Compared to values typically observed from the mid-1970s through the mid-1990s, the following proton parameters are lower on average from 2009 through day 79 of 2013: solar wind speed and beta (?11%), temperature (?40%), thermal pressure (?55%), mass flux (?34%), momentum flux or dynamic pressure (?41%), energy flux (?48%), IMF magnitude (?31%), and radial component of the IMF (?38%). These results have important implications for the solar wind's interaction with planetary magnetospheres and the heliosphere's interaction with the local interstellar medium, with the proton dynamic pressure remaining near the lowest values observed in the space age: ?1.4 nPa, compared to ?2.4 nPa typically observed from the mid-1970s through the mid-1990s. The combination of lower magnetic flux emergence from the Sun (carried out in the solar wind as the IMF) and associated low power in the solar wind points to the causal relationship between them. Our results indicate that the low solar wind output is driven by an internal trend in the Sun that is longer than the ?11 yr solar cycle, and they suggest that this current weak solar maximum is driven by the same trend.

  19. Thirty-Year Solid Waste Generation Maximum and Minimum Forecast for SRS

    SciTech Connect (OSTI)

    Thomas, L.C.

    1994-10-01

    This report is the third phase (Phase III) of the Thirty-Year Solid Waste Generation Forecast for Facilities at the Savannah River Site (SRS). Phase I of the forecast, Thirty-Year Solid Waste Generation Forecast for Facilities at SRS, forecasts the yearly quantities of low-level waste (LLW), hazardous waste, mixed waste, and transuranic (TRU) wastes generated over the next 30 years by operations, decontamination and decommissioning and environmental restoration (ER) activities at the Savannah River Site. The Phase II report, Thirty-Year Solid Waste Generation Forecast by Treatability Group (U), provides a 30-year forecast by waste treatability group for operations, decontamination and decommissioning, and ER activities. In addition, a 30-year forecast by waste stream has been provided for operations in Appendix A of the Phase II report. The solid wastes stored or generated at SRS must be treated and disposed of in accordance with federal, state, and local laws and regulations. To evaluate, select, and justify the use of promising treatment technologies and to evaluate the potential impact to the environment, the generic waste categories described in the Phase I report were divided into smaller classifications with similar physical, chemical, and radiological characteristics. These smaller classifications, defined within the Phase II report as treatability groups, can then be used in the Waste Management Environmental Impact Statement process to evaluate treatment options. The waste generation forecasts in the Phase II report includes existing waste inventories. Existing waste inventories, which include waste streams from continuing operations and stored wastes from discontinued operations, were not included in the Phase I report. Maximum and minimum forecasts serve as upper and lower boundaries for waste generation. This report provides the maximum and minimum forecast by waste treatability group for operation, decontamination and decommissioning, and ER activities.

  20. Evaluation of methods to predict safe welding conditions and maximum HAZ hardness in steel welding

    SciTech Connect (OSTI)

    Tronskar, J.P.

    1995-02-01

    During the last ten years new structural steels of improved weldability have been introduced. In particular, structural steels for the fabrication of offshore structures have been greatly improved in this respect throughout this period. These steels have lean chemical compositions which are generally outside the range for which the existing HAZ hardness criteria and the International Institute of Welding carbon equivalent (CEIIW) formula were originally developed. This paper presents the results from investigations of the weldability of three normalized (R{sub e} min 350 MPa) and three quenched and tempered (R{sub e} min 500 MPa) offshore structural steels. Weldability testing was conducted to study the relative performance of the different steels and to obtain a comparison between the capability of the different methods to predict safe welding conditions to avoid cold cracking in steel welding. It has become a widespread practice in welding high-strength steels to incorporate maximum HAZ hardness restrictions in fabrication specifications, particularly so in the offshore industry. This paper presents some of the more successful approaches proposed to date and compares their performance.

  1. Parametric study on maximum transportable distance and cost for thermal energy transportation using various coolants

    SciTech Connect (OSTI)

    Su-Jong Yoon; Piyush Sabharwall

    2014-07-01

    The operation temperature of advanced nuclear reactors is generally higher than commercial light water reactors and thermal energy from advanced nuclear reactor can be used for various purposes such as district heating, desalination, hydrogen production and other process heat applications, etc. The process heat industry/facilities will be located outside the nuclear island due to safety measures. This thermal energy from the reactor has to be transported a fair distance. In this study, analytical analysis was conducted to identify the maximum distance that thermal energy could be transported using various coolants such as molten-salts, helium and water by varying the pipe diameter and mass flow rate. The cost required to transport each coolant was also analyzed. The coolants analyzed are molten salts (such as: KClMgCl2, LiF-NaF-KF (FLiNaK) and KF-ZrF4), helium and water. Fluoride salts are superior because of better heat transport characteristics but chloride salts are most economical for higher temperature transportation purposes. For lower temperature water is a possible alternative when compared with He, because low pressure He requires higher pumping power which makes the process very inefficient and economically not viable for both low and high temperature application.

  2. Robust Maximum Lifetime Routing and Energy Allocation in Wireless Sensor Networks

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Paschalidis, Ioannis Ch.; Wu, Ruomin

    2012-01-01

    We consider the maximum lifetime routing problem in wireless sensor networks in two settings: (a) when nodes’ initial energy is given and (b) when it is subject to optimization. The optimal solution and objective value provide optimal flows and the corresponding predicted lifetime, respectively. We stipulate that there is uncertainty in various network parameters (available energy and energy depletion rates). In setting (a) we show that for specific, yet typical, network topologies, the actual network lifetime will reach the predicted value with a probability that converges to zero as the number of nodes grows large. In setting (b) the samemore » result holds for all topologies. We develop a series of robust problem formulations, ranging from pessimistic to optimistic. A set of parameters enable the tuning of the conservatism of the formulation to obtain network flows with a desirably high probability that the corresponding lifetime prediction is achieved. We establish a number of properties for the robust network flows and energy allocations and provide numerical results to highlight the tradeoff between predicted lifetime and the probability achieved. Further, we analyze an interesting limiting regime of massively deployed sensor networks and essentially solve a continuous version of the problem.« less

  3. Extended maximum likelihood halo-independent analysis of dark matter direct detection data

    SciTech Connect (OSTI)

    Gelmini, Graciela B.; Georgescu, Andreea; Gondolo, Paolo; Huh, Ji-Haeng

    2015-11-24

    We extend and correct a recently proposed maximum-likelihood halo-independent method to analyze unbinned direct dark matter detection data. Instead of the recoil energy as independent variable we use the minimum speed a dark matter particle must have to impart a given recoil energy to a nucleus. This has the advantage of allowing us to apply the method to any type of target composition and interaction, e.g. with general momentum and velocity dependence, and with elastic or inelastic scattering. We prove the method and provide a rigorous statistical interpretation of the results. As first applications, we find that for dark matter particles with elastic spin-independent interactions and neutron to proton coupling ratio f{sub n}/f{sub p}=−0.7, the WIMP interpretation of the signal observed by CDMS-II-Si is compatible with the constraints imposed by all other experiments with null results. We also find a similar compatibility for exothermic inelastic spin-independent interactions with f{sub n}/f{sub p}=−0.8.

  4. Maximum Reasonable Radioxenon Releases from Medical Isotope Production Facilities and Their Effect on Monitoring Nuclear Explosions

    SciTech Connect (OSTI)

    Bowyer, Ted W.; Kephart, Rosara F.; Eslinger, Paul W.; Friese, Judah I.; Miley, Harry S.; Saey, Paul R.

    2013-01-01

    Fission gases such as 133Xe are used extensively for monitoring the world for signs of nuclear testing in systems such as the International Monitoring System (IMS). These gases are also produced by nuclear reactors and by fission production of 99Mo for medical use. Recently, medical isotope production facilities have been identified as the major contributor to the background of radioactive xenon isotopes (radioxenon) in the atmosphere (Saey, et al., 2009). These releases pose a potential future problem for monitoring nuclear explosions if not addressed. As a starting point, a maximum acceptable daily xenon emission rate was calculated, that is both scientifically defendable as not adversely affecting the IMS, but also consistent with what is possible to achieve in an operational environment. This study concludes that an emission of 5×109 Bq/day from a medical isotope production facility would be both an acceptable upper limit from the perspective of minimal impact to monitoring stations, but also appears to be an achievable limit for large isotope producers.

  5. ESTIMATE OF SOLAR MAXIMUM USING THE 1-8 GEOSTATIONARY OPERATIONAL ENVIRONMENTAL SATELLITES X-RAY MEASUREMENTS

    SciTech Connect (OSTI)

    Winter, L. M.; Balasubramaniam, K. S.

    2014-10-01

    We present an alternate method of determining the progression of the solar cycle through an analysis of the solar X-ray background. Our results are based on the NOAA Geostationary Operational Environmental Satellites (GOES) X-ray data in the 1-8 band from 1986 to the present, covering solar cycles 22, 23, and 24. The X-ray background level tracks the progression of the solar cycle through its maximum and minimum. Using the X-ray data, we can therefore make estimates of the solar cycle progression and the date of solar maximum. Based upon our analysis, we conclude that the Sun reached its hemisphere-averaged maximum in solar cycle 24 in late 2013. This is within six months of the NOAA prediction of a maximum in spring 2013.

  6. Maximum Diameter Measurements of Aortic Aneurysms on Axial CT Images After Endovascular Aneurysm Repair: Sufficient for Follow-up?

    SciTech Connect (OSTI)

    Baumueller, Stephan Nguyen, Thi Dan Linh Goetti, Robert Paul; Lachat, Mario; Seifert, Burkhardt; Pfammatter, Thomas Frauenfelder, Thomas

    2011-12-15

    Purpose: To assess the accuracy of maximum diameter measurements of aortic aneurysms after endovascular aneurysm repair (EVAR) on axial computed tomographic (CT) images in comparison to maximum diameter measurements perpendicular to the intravascular centerline for follow-up by using three-dimensional (3D) volume measurements as the reference standard. Materials and Methods: Forty-nine consecutive patients (73 {+-} 7.5 years, range 51-88 years), who underwent EVAR of an infrarenal aortic aneurysm were retrospectively included. Two blinded readers twice independently measured the maximum aneurysm diameter on axial CT images performed at discharge, and at 1 and 2 years after intervention. The maximum diameter perpendicular to the centerline was automatically measured. Volumes of the aortic aneurysms were calculated by dedicated semiautomated 3D segmentation software (3surgery, 3mensio, the Netherlands). Changes in diameter of 0.5 cm and in volume of 10% were considered clinically significant. Intra- and interobserver agreements were calculated by intraclass correlations (ICC) in a random effects analysis of variance. The two unidimensional measurement methods were correlated to the reference standard. Results: Intra- and interobserver agreements for maximum aneurysm diameter measurements were excellent (ICC = 0.98 and ICC = 0.96, respectively). There was an excellent correlation between maximum aneurysm diameters measured on axial CT images and 3D volume measurements (r = 0.93, P < 0.001) as well as between maximum diameter measurements perpendicular to the centerline and 3D volume measurements (r = 0.93, P < 0.001). Conclusion: Measurements of maximum aneurysm diameters on axial CT images are an accurate, reliable, and robust method for follow-up after EVAR and can be used in daily routine.

  7. 2011-07 "Maximum Utilization of WIPP by Increasing MDA G TRU Shipments" |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy 7 "Maximum Utilization of WIPP by Increasing MDA G TRU Shipments" 2011-07 "Maximum Utilization of WIPP by Increasing MDA G TRU Shipments" The intent of this recommendation is to ensure optimization of WIPP shipment schedules while helping to keep commitments to Consent Order milestones at MDA-G. Rec 2011-07 - July 27, 2011 (78.0

  8. Maximum likelihood Bayesian model averaging and its predictive analysis for groundwater reactive transport models

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Lu, Dan; Ye, Ming; Curtis, Gary P.

    2015-08-01

    While Bayesian model averaging (BMA) has been widely used in groundwater modeling, it is infrequently applied to groundwater reactive transport modeling because of multiple sources of uncertainty in the coupled hydrogeochemical processes and because of the long execution time of each model run. To resolve these problems, this study analyzed different levels of uncertainty in a hierarchical way, and used the maximum likelihood version of BMA, i.e., MLBMA, to improve the computational efficiency. Our study demonstrates the applicability of MLBMA to groundwater reactive transport modeling in a synthetic case in which twenty-seven reactive transport models were designed to predict themore » reactive transport of hexavalent uranium (U(VI)) based on observations at a former uranium mill site near Naturita, CO. Moreover, these reactive transport models contain three uncertain model components, i.e., parameterization of hydraulic conductivity, configuration of model boundary, and surface complexation reactions that simulate U(VI) adsorption. These uncertain model components were aggregated into the alternative models by integrating a hierarchical structure into MLBMA. The modeling results of the individual models and MLBMA were analyzed to investigate their predictive performance. The predictive logscore results show that MLBMA generally outperforms the best model, suggesting that using MLBMA is a sound strategy to achieve more robust model predictions relative to a single model. MLBMA works best when the alternative models are structurally distinct and have diverse model predictions. When correlation in model structure exists, two strategies were used to improve predictive performance by retaining structurally distinct models or assigning smaller prior model probabilities to correlated models. Since the synthetic models were designed using data from the Naturita site, the results of this study are expected to provide guidance for real-world modeling. Finally

  9. Maximum likelihood Bayesian model averaging and its predictive analysis for groundwater reactive transport models

    SciTech Connect (OSTI)

    Lu, Dan; Ye, Ming; Curtis, Gary P.

    2015-08-01

    While Bayesian model averaging (BMA) has been widely used in groundwater modeling, it is infrequently applied to groundwater reactive transport modeling because of multiple sources of uncertainty in the coupled hydrogeochemical processes and because of the long execution time of each model run. To resolve these problems, this study analyzed different levels of uncertainty in a hierarchical way, and used the maximum likelihood version of BMA, i.e., MLBMA, to improve the computational efficiency. Our study demonstrates the applicability of MLBMA to groundwater reactive transport modeling in a synthetic case in which twenty-seven reactive transport models were designed to predict the reactive transport of hexavalent uranium (U(VI)) based on observations at a former uranium mill site near Naturita, CO. Moreover, these reactive transport models contain three uncertain model components, i.e., parameterization of hydraulic conductivity, configuration of model boundary, and surface complexation reactions that simulate U(VI) adsorption. These uncertain model components were aggregated into the alternative models by integrating a hierarchical structure into MLBMA. The modeling results of the individual models and MLBMA were analyzed to investigate their predictive performance. The predictive logscore results show that MLBMA generally outperforms the best model, suggesting that using MLBMA is a sound strategy to achieve more robust model predictions relative to a single model. MLBMA works best when the alternative models are structurally distinct and have diverse model predictions. When correlation in model structure exists, two strategies were used to improve predictive performance by retaining structurally distinct models or assigning smaller prior model probabilities to correlated models. Since the synthetic models were designed using data from the Naturita site, the results of this study are expected to provide guidance for real-world modeling. Finally, limitations of

  10. Setting the Renormalization Scale in QCD: The Principle of Maximum Conformality

    SciTech Connect (OSTI)

    Brodsky, Stanley J.; Di Giustino, Leonardo; /SLAC

    2011-08-19

    A key problem in making precise perturbative QCD predictions is the uncertainty in determining the renormalization scale {mu} of the running coupling {alpha}{sub s}({mu}{sup 2}): The purpose of the running coupling in any gauge theory is to sum all terms involving the {beta} function; in fact, when the renormalization scale is set properly, all non-conformal {beta} {ne} 0 terms in a perturbative expansion arising from renormalization are summed into the running coupling. The remaining terms in the perturbative series are then identical to that of a conformal theory; i.e., the corresponding theory with {beta} = 0. The resulting scale-fixed predictions using the 'principle of maximum conformality' (PMC) are independent of the choice of renormalization scheme - a key requirement of renormalization group invariance. The results avoid renormalon resummation and agree with QED scale-setting in the Abelian limit. The PMC is also the theoretical principle underlying the BLM procedure, commensurate scale relations between observables, and the scale-setting method used in lattice gauge theory. The number of active flavors nf in the QCD {beta} function is also correctly determined. We discuss several methods for determining the PMC/BLM scale for QCD processes. We show that a single global PMC scale, valid at leading order, can be derived from basic properties of the perturbative QCD cross section. The elimination of the renormalization scheme ambiguity using the PMC will not only increase the precision of QCD tests, but it will also increase the sensitivity of collider experiments to new physics beyond the Standard Model.

  11. SSL Pricing and Efficacy Trend Analysis for Utility Program Planning

    SciTech Connect (OSTI)

    Tuenge, Jason R.

    2013-10-01

    An LED lamp or luminaire can generally be found that matches or exceeds the efficacy of benchmark technologies in a given product category, and LED products continue to expand into ever-higher lumen output niches. However, the price premium for LED continues to pose a barrier to adoption in many applications, in spite of expected savings from reduced energy use and maintenance. Other factors—such as dimmability and quality of light—can also present challenges. The appropriate type, timing, and magnitude of energy efficiency activities will vary from organization to organization based on local variables and the method of evaluation. A number of factors merit consideration when prioritizing activities for development. Category-specific projections for pricing and efficacy are provided herein to assist in efficiency program planning efforts.

  12. Evaluation of a photovoltaic energy mechatronics system with a built-in quadratic maximum power point tracking algorithm

    SciTech Connect (OSTI)

    Chao, R.M.; Ko, S.H.; Lin, I.H.; Pai, F.S.; Chang, C.C.

    2009-12-15

    The historically high cost of crude oil price is stimulating research into solar (green) energy as an alternative energy source. In general, applications with large solar energy output require a maximum power point tracking (MPPT) algorithm to optimize the power generated by the photovoltaic effect. This work aims to provide a stand-alone solution for solar energy applications by integrating a DC/DC buck converter to a newly developed quadratic MPPT algorithm along with its appropriate software and hardware. The quadratic MPPT method utilizes three previously used duty cycles with their corresponding power outputs. It approaches the maximum value by using a second order polynomial formula, which converges faster than the existing MPPT algorithm. The hardware implementation takes advantage of the real-time controller system from National Instruments, USA. Experimental results have shown that the proposed solar mechatronics system can correctly and effectively track the maximum power point without any difficulties. (author)

  13. Application of the Principle of Maximum Conformality to Top-Pair Production

    SciTech Connect (OSTI)

    Brodsky, Stanley J.; Wu, Xing-Gang; /SLAC /Chongqing U.

    2013-05-13

    A major contribution to the uncertainty of finite-order perturbative QCD predictions is the perceived ambiguity in setting the renormalization scale {mu}{sub r}. For example, by using the conventional way of setting {mu}{sub r} {element_of} [m{sub t}/2, 2m{sub t}], one obtains the total t{bar t} production cross-section {sigma}{sub t{bar t}} with the uncertainty {Delta}{sigma}{sub t{bar t}}/{sigma}{sub t{bar t}} {approx} (+3%/-4%) at the Tevatron and LHC even for the present NNLO level. The Principle of Maximum Conformality (PMC) eliminates the renormalization scale ambiguity in precision tests of Abelian QED and non-Abelian QCD theories. By using the PMC, all nonconformal {l_brace}{beta}{sub i}{r_brace}-terms in the perturbative expansion series are summed into the running coupling constant, and the resulting scale-fixed predictions are independent of the renormalization scheme. The correct scale-displacement between the arguments of different renormalization schemes is automatically set, and the number of active flavors n{sub f} in the {l_brace}{beta}{sub i}{r_brace}-function is correctly determined. The PMC is consistent with the renormalization group property that a physical result is independent of the renormalization scheme and the choice of the initial renormalization scale {mu}{sub r}{sup init}. The PMC scale {mu}{sub r}{sup PMC} is unambiguous at finite order. Any residual dependence on {mu}{sub r}{sup init} for a finite-order calculation will be highly suppressed since the unknown higher-order {l_brace}{beta}{sub i}{r_brace}-terms will be absorbed into the PMC scales higher-order perturbative terms. We find that such renormalization group invariance can be satisfied to high accuracy for {sigma}{sub t{bar t}} at the NNLO level. In this paper we apply PMC scale-setting to predict the t{bar t} cross-section {sigma}{sub t{bar t}} at the Tevatron and LHC colliders. It is found that {sigma}{sub t{bar t}} remains almost unchanged by varying {mu}{sub r}{sup init

  14. Efficacy of Lower-Body Shielding in Computed Tomography Fluoroscopy-Guided Interventions

    SciTech Connect (OSTI)

    Mahnken, Andreas H.; Sedlmair, Martin; Ritter, Christine; Banckwitz, Rosemarie; Flohr, Thomas

    2012-12-15

    Purpose: Computed tomography (CT) fluoroscopy-guided interventions pose relevant radiation exposure to the interventionalist. The goal of this study was to analyze the efficacy of lower-body shielding as a simple structural method for decreasing radiation dose to the interventionalist without limiting access to the patient. Material and Methods: All examinations were performed with a 128-slice dual source CT scanner (12 Multiplication-Sign 1.2-mm collimation; 120 kV; and 20, 40, 60, and 80 mAs) and an Alderson-Rando phantom. Scatter radiation was measured with an ionization chamber and a digital dosimeter at standardized positions and heights with and without a lower-body lead shield (0.5-mm lead equivalent; Kenex, Harlow, UK). Dose decreases were computed for the different points of measurement. Results: On average, lower-body shielding decreased scatter radiation by 38.2% within a 150-cm radius around the shielding. This decrease is most significant close to the gantry opening and at low heights of 50 and 100 cm above the floor with a maximum decrease of scatter radiation of 95.9% close to the scanner's isocentre. With increasing distance to the gantry opening, the effect decreased. There is almost no dose decrease effect at {>=}150 above the floor. Scatter radiation and its decrease were linearly correlated with the tube current-time product (r{sup 2} = 0.99), whereas percent scatter radiation decrease was independent of the tube current-time product. Conclusion: Lower-body shielding is an effective way to decrease radiation exposure to the interventionalist and should routinely be used in CT fluoroscopy-guided interventions.

  15. Room at the Mountain: Estimated Maximum Amounts of Commercial Spent Nuclear Fuel Capable of Disposal in a Yucca Mountain Repository

    SciTech Connect (OSTI)

    Kessler, John H.; Kemeny, John; King, Fraser; Ross, Alan M.; Ross, Benjamen

    2006-07-01

    The purpose of this paper is to present an initial analysis of the maximum amount of commercial spent nuclear fuel (CSNF) that could be emplaced into a geological repository at Yucca Mountain. This analysis identifies and uses programmatic, material, and geological constraints and factors that affect this estimation of maximum amount of CSNF for disposal. The conclusion of this initial analysis is that the current legislative limit on Yucca Mountain disposal capacity, 63,000 MTHM of CSNF, is a small fraction of the available physical capacity of the Yucca Mountain system assuming the current high-temperature operating mode (HTOM) design. EPRI is confident that at least four times the legislative limit for CSNF ({approx}260,000 MTHM) can be emplaced in the Yucca Mountain system. It is possible that with additional site characterization, upwards of nine times the legislative limit ({approx}570,000 MTHM) could be emplaced. (authors)

  16. Measurement of the Depth of Maximum of Extensive Air Showers above 10^18 eV

    SciTech Connect (OSTI)

    Abraham, J.; Abreu, P.; Aglietta, M.; Ahn, E.J.; Allard, D.; Allekotte, I.; Allen, J.; Alvarez-Muniz, J.; Ambrosio, M.; Anchordoqui, L.; Andringa, S.; /Lisbon, IST /Boskovic Inst., Zagreb

    2010-02-01

    We describe the measurement of the depth of maximum, X{sub max}, of the longitudinal development of air showers induced by cosmic rays. Almost 4000 events above 10{sup 18} eV observed by the fluorescence detector of the Pierre Auger Observatory in coincidence with at least one surface detector station are selected for the analysis. The average shower maximum was found to evolve with energy at a rate of (106{sub -21}{sup +35}) g/cm{sup 2}/decade below 10{sup 18.24 {+-} 0.05}eV, and (24 {+-} 3) g/cm{sup 2}/decade above this energy. The measured shower-to-shower fluctuations decrease from about 55 to 26 g/cm{sup 2}. The interpretation of these results in terms of the cosmic ray mass composition is briefly discussed.

  17. The most luminous z ∼ 9-10 galaxy candidates yet found: The luminosity function, cosmic star-formation rate, and the first mass density estimate at 500 Myr

    SciTech Connect (OSTI)

    Oesch, P. A.; Illingworth, G. D.; Magee, D.; Van Dokkum, P. G.; Momcheva, I.; Ashby, M. L. N.; Fazio, G. G.; Huang, J.-S.; Willner, S. P.; Gonzalez, V.; Trenti, M.; Brammer, G. B.; Skelton, R. E.; Spitler, L. R.

    2014-05-10

    We present the discovery of four surprisingly bright (H {sub 160} ∼ 26-27 mag AB) galaxy candidates at z ∼ 9-10 in the complete HST CANDELS WFC3/IR GOODS-N imaging data, doubling the number of z ∼ 10 galaxy candidates that are known, just ∼500 Myr after the big bang. Two similarly bright sources are also detected in a reanalysis of the GOODS-S data set. Three of the four galaxies in GOODS-N are significantly detected at 4.5σ-6.2σ in the very deep Spitzer/IRAC 4.5 μm data, as is one of the GOODS-S candidates. Furthermore, the brightest of our candidates (at z = 10.2 ± 0.4) is robustly detected also at 3.6 μm (6.9σ), revealing a flat UV spectral energy distribution with a slope β = –2.0 ± 0.2, consistent with demonstrated trends with luminosity at high redshift. Thorough testing and use of grism data excludes known low-redshift contamination at high significance, including single emission-line sources, but as-yet unknown low redshift sources could provide an alternative solution given the surprising luminosity of these candidates. Finding such bright galaxies at z ∼ 9-10 suggests that the luminosity function for luminous galaxies might evolve in a complex way at z > 8. The cosmic star formation rate density still shows, however, an order-of-magnitude increase from z ∼ 10 to z ∼ 8 since the dominant contribution comes from low-luminosity sources. Based on the IRAC detections, we derive galaxy stellar masses at z ∼ 10, finding that these luminous objects are typically 10{sup 9} M {sub ☉}. This allows for a first estimate of the cosmic stellar mass density at z ∼ 10 resulting in log{sub 10} ρ{sub ∗}=4.7{sub −0.8}{sup +0.5} M {sub ☉} Mpc{sup –3} for galaxies brighter than M {sub UV} ∼ –18. The remarkable brightness, and hence luminosity, of these z ∼ 9-10 candidates will enable deep spectroscopy to determine their redshift and nature, and highlights the opportunity for the James Webb Space Telescope to map the buildup of

  18. SUZAKU VIEW OF THE SWIFT/BAT ACTIVE GALACTIC NUCLEI. V. TORUS STRUCTURE OF TWO LUMINOUS RADIO-LOUD ACTIVE GALACTIC NUCLEI (3C 206 AND PKS 0707-35)

    SciTech Connect (OSTI)

    Tazaki, Fumie; Ueda, Yoshihiro; Terashima, Yuichi; Mushotzky, Richard F.; Tombesi, Francesco

    2013-07-20

    We present the results from broadband X-ray spectral analysis of 3C 206 and PKS 0707-35 with Suzaku and Swift/BAT, two of the most luminous unobscured and obscured radio-loud active galactic nuclei (AGNs) with hard X-ray luminosities of 10{sup 45.5} erg s{sup -1} and 10{sup 44.9} erg s{sup -1} (14-195 keV), respectively. Based on the radio core luminosity, we estimate that the X-ray spectrum of 3C 206 contains a significant ({approx}60% in the 14-195 keV band) contribution from the jet, while it is negligible in PKS 0707-35. We can successfully model the spectra with the jet component (for 3C 206), the transmitted emission, and two reflection components from the torus and the accretion disk. The reflection strengths from the torus are found to be R{sub torus}({identical_to} {Omega}/2{pi}) = 0.29 {+-} 0.18 and 0.41 {+-} 0.18 for 3C 206 and PKS 0707-35, respectively, which are smaller than those in typical Seyfert galaxies. Utilizing the torus model by Ikeda et al., we quantify the relation between the half-opening angle of a torus ({theta}{sub oa}) and the equivalent width of an iron-K line. The observed equivalent width of 3C 206, < 71 eV, constrains the column density in the equatorial plane to N{sub H}{sup eq} <10{sup 23} cm{sup -2}, or the half-opening angle to {theta}{sub oa} > 80 Degree-Sign if N{sub H}{sup eq} =10{sup 24} cm{sup -2} is assumed. That of PKS 0707-35, 72 {+-} 36 eV, is consistent with N{sub H}{sup eq} {approx}10{sup 23} cm{sup -2}. Our results suggest that the tori in luminous radio-loud AGNs are only poorly developed. The trend is similar to that seen in radio-quiet AGNs, implying that the torus structure is not different between AGNs with jets and without jets.

  19. Test report on the Abacus 30 kW bimode{reg_sign} inverter and maximum power tracker (MPT)

    SciTech Connect (OSTI)

    Bonn, R.; Ginn, J.; Zirzow, J.

    1995-06-01

    Sandia National Laboratories conducts the photovoltaic balance of systems (BOS) program, which is sponsored by the US Department of Energy`s Office of Energy Management. Under this program, SNL lets commercialization contracts and conducts a laboratory program designed to advance BOS technology, improve BOS component reliability, and reduce the BOS life-cycle-cost. This report details the testing of the first large US manufactured hybrid inverter and its associated maximum power tracker.

  20. Optimum coil shape for a given volume of conductor to obtain maximum central field in an air core solenoid

    SciTech Connect (OSTI)

    Hernandez, P.

    1995-02-01

    This paper is an expansion of engineering notes prepared in 1961 to address the question of how to wind circular coils so as to obtain the maximum axial field with the minimum volume of conductor. At the time this was a germain question because of the advent of superconducting wires which were in very limited supply, and the rapid push for generation of very high fields, with little concern for uniformity.

  1. Augmenting drug–carrier compatibility improves tumour nanotherapy efficacy

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Zhao, Yiming; Fay, Francois; Hak, Sjoerd; Manuel Perez-Aguilar, Jose; Sanchez-Gaytan, Brenda L.; Goode, Brandon; Duivenvoorden, Raphael; de Lange Davies, Catharina; Bjorkoy, Astrid; Weinstein, Harel; et al

    2016-04-13

    A major goal of cancer nanotherapy is to use nanoparticles as carriers for targeted delivery of anti-tumour agents. The drug–carrier association after intravenous administration is essential for efficient drug delivery to the tumour. However, a large number of currently available nanocarriers are self-assembled nanoparticles whose drug-loading stability is critically affected by the in vivo environment. Here we used in vivo FRET imaging to systematically investigate how drug–carrier compatibility affects drug release in a tumour mouse model. We found the drug’s hydrophobicity and miscibility with the nanoparticles are two independent key parameters that determine its accumulation in the tumour. Next, wemore » applied these findings to improve chemotherapeutic delivery by augmenting the parent drug’s compatibility; as a result, we achieved better antitumour efficacy. Lastly, our results help elucidate nanomedicines’ in vivo fate and provide guidelines for efficient drug delivery.« less

  2. Maximum mass of stable magnetized highly super-Chandrasekhar white dwarfs: stable solutions with varying magnetic fields

    SciTech Connect (OSTI)

    Das, Upasana; Mukhopadhyay, Banibrata E-mail: bm@physics.iisc.ernet.in

    2014-06-01

    We address the issue of stability of recently proposed significantly super-Chandrasekhar white dwarfs. We present stable solutions of magnetostatic equilibrium models for super-Chandrasekhar white dwarfs pertaining to various magnetic field profiles. This has been obtained by self-consistently including the effects of the magnetic pressure gradient and total magnetic density in a general relativistic framework. We estimate that the maximum stable mass of magnetized white dwarfs could be more than 3 solar mass. This is very useful to explain peculiar, overluminous type Ia supernovae which do not conform to the traditional Chandrasekhar mass-limit.

  3. Application of asymptotic expansions for maximum likelihood estimators errors to gravitational waves from binary mergers: The single interferometer case

    SciTech Connect (OSTI)

    Zanolin, M.; Vitale, S.; Makris, N.

    2010-06-15

    In this paper we apply to gravitational waves (GW) from the inspiral phase of binary systems a recently derived frequentist methodology to calculate analytically the error for a maximum likelihood estimate of physical parameters. We use expansions of the covariance and the bias of a maximum likelihood estimate in terms of inverse powers of the signal-to-noise ration (SNR)s where the square root of the first order in the covariance expansion is the Cramer Rao lower bound (CRLB). We evaluate the expansions, for the first time, for GW signals in noises of GW interferometers. The examples are limited to a single, optimally oriented, interferometer. We also compare the error estimates using the first two orders of the expansions with existing numerical Monte Carlo simulations. The first two orders of the covariance allow us to get error predictions closer to what is observed in numerical simulations than the CRLB. The methodology also predicts a necessary SNR to approximate the error with the CRLB and provides new insight on the relationship between waveform properties, SNR, dimension of the parameter space and estimation errors. For example the timing match filtering can achieve the CRLB only if the SNR is larger than the Kurtosis of the gravitational wave spectrum and the necessary SNR is much larger if other physical parameters are also unknown.

  4. The effect of maximum-allowable payload temperature on the mass of a multimegawatt space-based platform

    SciTech Connect (OSTI)

    Dobranich, D.

    1987-08-01

    Calculations were performed to determine the mass of a space-based platform as a function of the maximum-allowed operating temperature of the electrical equipment within the platform payload. Two computer programs were used in conjunction to perform these calculations. The first program was used to determine the mass of the platform reactor, shield, and power conversion system. The second program was used to determine the mass of the main and secondary radiators of the platform. The main radiator removes the waste heat associated with the power conversion system and the secondary radiator removes the waste heat associated with the platform payload. These calculations were performed for both Brayton and Rankine cycle platforms with two different types of payload cooling systems: a pumped-loop system (a heat exchanger with a liquid coolant) and a refrigerator system. The results indicate that increases in the maximum-allowed payload temperature offer significant platform mass savings for both the Brayton and Rankine cycle platforms with either the pumped-loop or refrigerator payload cooling systems. Therefore, with respect to platform mass, the development of high temperature electrical equipment would be advantageous. 3 refs., 24 figs., 7 tabs.

  5. Optimization of a Nucleic Acids united-RESidue 2-Point model (NARES-2P) with a maximum-likelihood approach

    SciTech Connect (OSTI)

    He, Yi; Scheraga, Harold A.; Liwo, Adam

    2015-12-28

    Coarse-grained models are useful tools to investigate the structural and thermodynamic properties of biomolecules. They are obtained by merging several atoms into one interaction site. Such simplified models try to capture as much as possible information of the original biomolecular system in all-atom representation but the resulting parameters of these coarse-grained force fields still need further optimization. In this paper, a force field optimization method, which is based on maximum-likelihood fitting of the simulated to the experimental conformational ensembles and least-squares fitting of the simulated to the experimental heat-capacity curves, is applied to optimize the Nucleic Acid united-RESidue 2-point (NARES-2P) model for coarse-grained simulations of nucleic acids recently developed in our laboratory. The optimized NARES-2P force field reproduces the structural and thermodynamic data of small DNA molecules much better than the original force field.

  6. Frequency dependence of the maximum operating temperature for quantum-cascade lasers up to 5.4 THz

    SciTech Connect (OSTI)

    Wienold, M.; Röben, B.; Lü, X.; Rozas, G.; Schrottke, L.; Biermann, K.; Grahn, H. T.

    2015-11-16

    We report on the observation of an approximately linear reduction in the maximum operating temperature with an increasing emission frequency for terahertz quantum-cascade lasers between 4.2 and 5.4 THz. These lasers are based on the same design type, but vary in period length and barrier height for the cascade structure. The sample emitting at the highest frequency around 5.4 THz can be operated in pulsed mode up to 56 K. We identify an additional relaxation channel for electrons by longitudinal optical phonon scattering from the upper to the lower laser level and increasing optical losses toward higher frequencies as major processes, leading to the observed temperature behavior.

  7. Analysis of offsite emergency planning zones for the Rocky Flats Plant. Maximum credible accident fourth (1988--1991) review

    SciTech Connect (OSTI)

    Stalker, A.C.

    1992-05-01

    The purpose of the Fourth (1988--1990) Maximum Credible Accident (MCA) Review was to determine if changes in waste storage or operational inventories at the Rocky Flats Plant have affected the basis for the current MCA. This report documents the Fourth MCA Review and the activities performed to identify and affirm the inventories-at-risk and estimate the release of Pu/Am that might occur due to the MCA. The State of Colorado has defined, for its Emergency Planning Zone (EPZ) determination, that the MCA is a release of 100 grams of respirable Pu (and/or its equivalent as americium) dispersed into the RFP ambient air, regardless of the specific scenario that produces the release.

  8. Basement Fill Model Evaluation of Maximum Radionuclide Concentrations for Initial Suite of Radionuclides. Zion Station Restoration Project

    SciTech Connect (OSTI)

    Sullivan, Terry

    2014-12-10

    ZionSolutions is in the process of decommissioning the Zion Nuclear Power Plant in order to establish a new water treatment plant. There is some residual radioactive particles from the plant which need to be brought down to levels so an individual who receives water from the new treatment plant does not receive a radioactive dose in excess of 25 mrem/y⁻¹ as specified in 10 CFR 20 Subpart E. The objectives of this report are: (a) To present a simplified conceptual model for release from the buildings with residual subsurface structures that can be used to provide an upper bound on radionuclide concentrations in the fill material and the water in the interstitial spaces of the fill. (b) Provide maximum water concentrations and the corresponding amount of mass sorbed to the solid fill material that could occur in each building for use by ZSRP in selecting ROCs for detailed dose assessment calculations.

  9. Changes in maximum and minimal temperatures at high elevation stations in the central Andes of South America

    SciTech Connect (OSTI)

    Quintana-Gomez, R.A.

    1997-11-01

    Temperature trends and deviations were evaluated for the central Andes portion of Bolivia. Data were collected primarily from stations located at very high altitude (3,000 m above sea level and higher) for a 73-year period from 1918 to 1990. The analysis determined maximum and minimum temperature trends and the daily temperature range (DTR) at each station. The minimum temperature series showed a rather sustained increase starting in the 1960s and continuing to the present, and a reduction of the differential rate of warming for the same interval. The high elevation, rural area data appears to reinforce evidence of a global and generalized rise of minimum temperature and decrease of the DTR. 3 refs., 2 figs., 1 tab.

  10. Potential Impact of Adopting Maximum Technologies as Minimum Efficiency Performance Standards in the U.S. Residential Sector

    SciTech Connect (OSTI)

    Letschert, Virginie; Desroches, Louis-Benoit; McNeil, Michael; Saheb, Yamina

    2010-05-03

    The US Department of Energy (US DOE) has placed lighting and appliance standards at a very high priority of the U.S. energy policy. However, the maximum energy savings and CO2 emissions reduction achievable via minimum efficiency performance standards (MEPS) has not yet been fully characterized. The Bottom Up Energy Analysis System (BUENAS), first developed in 2007, is a global, generic, and modular tool designed to provide policy makers with estimates of potential impacts resulting from MEPS for a variety of products, at the international and/or regional level. Using the BUENAS framework, we estimated potential national energy savings and CO2 emissions mitigation in the US residential sector that would result from the most aggressive policy foreseeable: standards effective in 2014 set at the current maximum technology (Max Tech) available on the market. This represents the most likely characterization of what can be maximally achieved through MEPS in the US. The authors rely on the latest Technical Support Documents and Analytical Tools published by the U.S. Department of Energy as a source to determine appliance stock turnover and projected efficiency scenarios of what would occur in the absence of policy. In our analysis, national impacts are determined for the following end uses: lighting, television, refrigerator-freezers, central air conditioning, room air conditioning, residential furnaces, and water heating. The analyzed end uses cover approximately 65percent of site energy consumption in the residential sector (50percent of the electricity consumption and 80percent of the natural gas and LPG consumption). This paper uses this BUENAS methodology to calculate that energy savings from Max Tech for the U.S. residential sector products covered in this paper will reach an 18percent reduction in electricity demand compared to the base case and 11percent in Natural Gas and LPG consumption by 2030 The methodology results in reductions in CO2 emissions of a similar

  11. Validation of a 4D-PET Maximum Intensity Projection for Delineation of an Internal Target Volume

    SciTech Connect (OSTI)

    Callahan, Jason; Kron, Tomas; Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne ; Schneider-Kolsky, Michal; Dunn, Leon; Thompson, Mick; Siva, Shankar; Aarons, Yolanda; Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne ; Binns, David; Hicks, Rodney J.; Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne

    2013-07-15

    Purpose: The delineation of internal target volumes (ITVs) in radiation therapy of lung tumors is currently performed by use of either free-breathing (FB) {sup 18}F-fluorodeoxyglucose-positron emission tomography-computed tomography (FDG-PET/CT) or 4-dimensional (4D)-CT maximum intensity projection (MIP). In this report we validate the use of 4D-PET-MIP for the delineation of target volumes in both a phantom and in patients. Methods and Materials: A phantom with 3 hollow spheres was prepared surrounded by air then water. The spheres and water background were filled with a mixture of {sup 18}F and radiographic contrast medium. A 4D-PET/CT scan was performed of the phantom while moving in 4 different breathing patterns using a programmable motion device. Nine patients with an FDG-avid lung tumor who underwent FB and 4D-PET/CT and >5 mm of tumor motion were included for analysis. The 3 spheres and patient lesions were contoured by 2 contouring methods (40% of maximum and PET edge) on the FB-PET, FB-CT, 4D-PET, 4D-PET-MIP, and 4D-CT-MIP. The concordance between the different contoured volumes was calculated using a Dice coefficient (DC). The difference in lung tumor volumes between FB-PET and 4D-PET volumes was also measured. Results: The average DC in the phantom using 40% and PET edge, respectively, was lowest for FB-PET/CT (DCAir = 0.72/0.67, DCBackground 0.63/0.62) and highest for 4D-PET/CT-MIP (DCAir = 0.84/0.83, DCBackground = 0.78/0.73). The average DC in the 9 patients using 40% and PET edge, respectively, was also lowest for FB-PET/CT (DC = 0.45/0.44) and highest for 4D-PET/CT-MIP (DC = 0.72/0.73). In the 9 lesions, the target volumes of the FB-PET using 40% and PET edge, respectively, were on average 40% and 45% smaller than the 4D-PET-MIP. Conclusion: A 4D-PET-MIP produces volumes with the highest concordance with 4D-CT-MIP across multiple breathing patterns and lesion sizes in both a phantom and among patients. Freebreathing PET/CT consistently

  12. Application of Maximum Likelihood Bayesian Model Averaging to Groundwater Flow and Transport at the Hanford Site 300 Area

    SciTech Connect (OSTI)

    Meyer, Philip D.; Ye, Ming; Neuman, Shlomo P.; Rockhold, Mark L.

    2008-06-01

    A methodology to systematically and quantitatively assess model predictive uncertainty was applied to saturated zone uranium transport at the 300 Area of the U.S. Department of Energy Hanford Site in Washington State, USA. The methodology extends Maximum Likelihood Bayesian Model Averaging (MLBMA) to account jointly for uncertainties due to the conceptual-mathematical basis of models, model parameters, and the scenarios to which the models are applied. Conceptual uncertainty was represented by postulating four alternative models of hydrogeology and uranium adsorption. Parameter uncertainties were represented by estimation covariances resulting from the joint calibration of each model to observed heads and uranium concentration. Posterior model probability was dominated by one model. Results demonstrated the role of model complexity and fidelity to observed system behavior in determining model probabilities, as well as the impact of prior information. Two scenarios representing alternative future behavior of the Columbia River adjacent to the site were considered. Predictive simulations carried out with the calibrated models illustrated the computation of model- and scenario-averaged predictions and how results can be displayed to clearly indicate the individual contributions to predictive uncertainty of the model, parameter, and scenario uncertainties. The application demonstrated the practicability of applying a comprehensive uncertainty assessment to large-scale, detailed groundwater flow and transport modelling.

  13. HUBBLE SPACE TELESCOPE ACS IMAGING OF THE GOALS SAMPLE: QUANTITATIVE STRUCTURAL PROPERTIES OF NEARBY LUMINOUS INFRARED GALAXIES WITH L{sub IR} > 10{sup 11.4} L{sub Sun}

    SciTech Connect (OSTI)

    Kim, D.-C.; Evans, A. S.; Privon, G. C. E-mail: aevans@virginia.edu; and others

    2013-05-10

    A Hubble Space Telescope/Advanced Camera for Surveys study of the structural properties of 85 luminous and ultraluminous (L{sub IR} > 10{sup 11.4} L{sub Sun }) infrared galaxies (LIRGs and ULIRGs) in the Great Observatories All-sky LIRG Survey (GOALS) sample is presented. Two-dimensional GALFIT analysis has been performed on F814W ''I-band'' images to decompose each galaxy, as appropriate, into bulge, disk, central point-spread function (PSF) and stellar bar components. The fraction of bulge-less disk systems is observed to be higher in LIRGs (35%) than in ULIRGs (20%), with the disk+bulge systems making up the dominant fraction of both LIRGs (55%) and ULIRGs (45%). Further, bulge+disk systems are the dominant late-stage merger galaxy type and are the dominant type for LIRGs and ULIRGs at almost every stage of galaxy-galaxy nuclear separation. The mean I-band host absolute magnitude of the GOALS galaxies is -22.64 {+-} 0.62 mag (1.8{sup +1.4}{sub -0.4} L{sup *}{sub I}), and the mean bulge absolute magnitude in GOALS galaxies is about 1.1 mag fainter than the mean host magnitude. Almost all ULIRGs have bulge magnitudes at the high end (-20.6 to -23.5 mag) of the GOALS bulge magnitude range. Mass ratios in the GOALS binary systems are consistent with most of the galaxies being the result of major mergers, and an examination of the residual-to-host intensity ratios in GOALS binary systems suggests that smaller companions suffer more tidal distortion than the larger companions. We find approximately twice as many bars in GOALS disk+bulge systems (32.8%) than in pure-disk mergers (15.9%) but most of the disk+bulge systems that contain bars are disk-dominated with small bulges. The bar-to-host intensity ratio, bar half-light radius, and bar ellipticity in GOALS galaxies are similar to those found in nearby spiral galaxies. The fraction of stellar bars decreases toward later merger stages and smaller nuclear separations, indicating that bars are destroyed as the merger

  14. EIS-0158: Supplemental Environmental Impact Statement to the 1979 Petroleum Production at Maximum Efficient Rate, Naval Petroleum Reserve No. 1(Elk Hills), Kern County, California (1993)

    Broader source: Energy.gov [DOE]

    The U.S. Department of Energy developed this EIS to assess the potential environmental impacts of the continued operation of the Naval Petroleum Reserve No. 1 at the Maximum Efficient Rate authorized by Public Law 94-258. This EIS supplements DOE/EIS-0012.

  15. SU-E-T-539: Maximum Energy of Helium and Carbon Ions Clinically Needed for Spine, Lung, Prostate and Pancreas Cancer

    SciTech Connect (OSTI)

    Pompos, A; Choy, H; Jia, X; Jiang, S; Timmerman, R

    2015-06-15

    Purpose: Maximum available kinetic energy of accelerated heavy ions is a critical parameter to consider during the establishment of a heavy ion therapy center. It dictates the maximum range in tissue and determines the size and cost of ion gantry. We have started planning our heavy ion therapy center and we report on the needed ion range. Methods: We analyzed 50 of random SBRT-spine, SBRT- lung, prostate and pancreatic cancer patients from our photon clinic. In the isocentric axial CT cut we recorded the maximum water equivalent depth (WED4Field) of PTV’s most distal edge in four cardinal directions and also in a beam direction that required the largest penetration, WEDGantry. These depths were then used to calculate the percentage of our patients we would be able to treat as a function of available maximum carbon and helium beam energy. Based on the Anterior-Posterior WED for lung patients and the maximum available ion energy we estimated the largest possible non-coplanar beam entry angle φ (deviation from vertical) in the isocentric vertical sagittal plane. Results: We found that if 430MeV/u C-12, equivalently 220MeV/u He-4, beams are available, more than 96% (98%) of all patients can be treated without any gantry restrictions (in cardinals angles only) respectively. If the energy is reduced to 400MeV/u C-12, equivalently 205MeV/u He-4, the above fractions reduce to 80% (87%) for prostate and 88% (97%) for other sites. This 7% energy decrease translates to almost 5% gantry size and cost decrease for both ions. These energy limits in combination with the WED in the AP direction for lung patients resulted in average non-coplanar angles of φ430MeV/u = 68°±8° and φ400MeV/u = 65°±10° if nozzle clearance permits them. Conclusion: We found that the two worldwide most common maximum carbon beam energies will treat above 80% of all our patients.

  16. A test of the 'one-point method' for estimating maximum carboxylation capacity from field-measured, light-saturated photosynthesis

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Martin G. De Kauwe; Serbin, Shawn P.; Lin, Yan -Shih; Wright, Ian J.; Medlyn, Belinda E.; Crous, Kristine Y.; Ellsworth, David S.; Maire, Vincent; Prentice, I. Colin; Atkin, Owen K.; et al

    2015-12-31

    Here, simulations of photosynthesis by terrestrial biosphere models typically need a specification of the maximum carboxylation rate (Vcmax). Estimating this parameter using A–Ci curves (net photosynthesis, A, vs intercellular CO2 concentration, Ci) is laborious, which limits availability of Vcmax data. However, many multispecies field datasets include net photosynthetic rate at saturating irradiance and at ambient atmospheric CO2 concentration (Asat) measurements, from which Vcmax can be extracted using a ‘one-point method’.

  17. Verification of maximum radial power peaking factor due to insertion of FPM-LEU target in the core of RSG-GAS reactor

    SciTech Connect (OSTI)

    Setyawan, Daddy; Rohman, Budi

    2014-09-30

    Verification of Maximum Radial Power Peaking Factor due to insertion of FPM-LEU target in the core of RSG-GAS Reactor. Radial Power Peaking Factor in RSG-GAS Reactor is a very important parameter for the safety of RSG-GAS reactor during operation. Data of radial power peaking factor due to the insertion of Fission Product Molybdenum with Low Enriched Uranium (FPM-LEU) was reported by PRSG to BAPETEN through the Safety Analysis Report RSG-GAS for FPM-LEU target irradiation. In order to support the evaluation of the Safety Analysis Report incorporated in the submission, the assessment unit of BAPETEN is carrying out independent assessment in order to verify safety related parameters in the SAR including neutronic aspect. The work includes verification to the maximum radial power peaking factor change due to the insertion of FPM-LEU target in RSG-GAS Reactor by computational method using MCNP5and ORIGEN2. From the results of calculations, the new maximum value of the radial power peaking factor due to the insertion of FPM-LEU target is 1.27. The results of calculations in this study showed a smaller value than 1.4 the limit allowed in the SAR.

  18. Strobe Light Deterrent Efficacy Test and Fish Behavior Determination at Grand Coulee Dam Third Powerplant Forebay

    SciTech Connect (OSTI)

    Simmons, Mary Ann; Johnson, Robert L.; McKinstry, Craig A.; Simmons, Carver S.; Cook, Chris B.; Brown, Richard S.; Tano, Daniel K.; Thorsten, Susan L.; Faber, Derrek M.; Lecaire, Richard; Francis, Stephen

    2004-01-01

    This report documents the third year of a four-year study to assess the efficacy of a prototype strobe light system to elicit a negative phototactic response in kokanee salmon (Oncorhynchus nerka) and rainbow trout (O. mykiss) in the forebay to the third powerplant at Grand Coulee Dam. This work was conducted for the Bonneville Power Administration, U.S. Department of Energy, by Pacific Northwest National Laboratory (PNNL) in conjunction with the Confederated Tribes of the Colville Reservation (Colville Confederated Tribes).

  19. OSRAM SYLVANIA Demonstrates 1,439-Lumen Downlight with Efficacy of 82 lm/W

    Broader source: Energy.gov [DOE]

    OSRAM SYLVANIA researchers have demonstrated a downlight luminaire that achieves 1,439 lumens at an efficacy of 82 lm/W in steady-state operation. These results exceed the project goals of achieving 1,300 lumens and 70 lm/W at a CCT of 3500K and CRI of 80. Improvements in LED chips, phosphors, optics, electronics, and thermal management at OSRAM all contributed to the higher-than-projected luminaire performance.

  20. Strobe Light Deterrent Efficacy Test and Fish Behavior Determination at Grand Coulee Dam Third Powerplant Forebay

    SciTech Connect (OSTI)

    Johnson, Robert L.; Simmons, Mary Ann; McKinstry, Craig A.; Simmons, Carver S.; Cook, Chris B.; Brown, Richard S.; Tano, Daniel K.; Thorsten, Susan L.; Faber, Derrek M.; Lecaire, Richard; Francis, Stephen

    2005-02-25

    This report documents the fourth year of a four-year study to assess the efficacy of a prototype strobe light system to elicit a negative phototactic response in kokanee salmon (Oncorhynchus nerka) and rainbow trout (O. mykiss) in the forebay to the third powerplant at Grand Coulee Dam. This work was conducted for the Bonneville Power Administration, U.S. Department of Energy, by Pacific Northwest National Laboratory (PNNL) in conjunction with the Confederated Tribes of the Colville Reservation (Colville Confederated Tribes).

  1. Buildings Energy Data Book: 5.6 Lighting

    Buildings Energy Data Book [EERE]

    9 Typical Efficacies and Lifetimes of Lamps (1) Current Technology CRI (2) Incandescent 10 - 19 97 Halogen 14 - 20 99 Fluorescent - T5 25 - 55 52 - 75 Fluorescent - T8 35 - 87 7,500 - 20,000 52 - 90 Fluorescent - T12 35 - 92 7,500 - 20,000 50 - 92 Compact Fluorescent 40 - 70 82 Mercury Vapor 25 - 50 15 - 50 Metal Halide 65 - 70 High-Pressure Sodium 22 Low-Pressure Sodium 0 Solid State Lighting 33-97 Note(s): Source(s): 18 - 180 18,000 20 - 100 15,000 - 50,000 1) Theoretical maximum luminous

  2. A test of the 'one-point method' for estimating maximum carboxylation capacity from field-measured, light-saturated photosynthesis

    SciTech Connect (OSTI)

    Martin G. De Kauwe; Serbin, Shawn P.; Lin, Yan -Shih; Wright, Ian J.; Medlyn, Belinda E.; Crous, Kristine Y.; Ellsworth, David S.; Maire, Vincent; Prentice, I. Colin; Atkin, Owen K.; Rogers, Alistair; Niinemets, Ulo; Meir, Patrick; Uddling, Johan; Togashi, Henrique F.; Tarvainen, Lasse; Weerasinghe, Lasantha K.; Evans, Bradley J.; Ishida, F. Yoko; Domingues, Tomas F.

    2015-12-31

    Here, simulations of photosynthesis by terrestrial biosphere models typically need a specification of the maximum carboxylation rate (Vcmax). Estimating this parameter using A–Ci curves (net photosynthesis, A, vs intercellular CO2 concentration, Ci) is laborious, which limits availability of Vcmax data. However, many multispecies field datasets include net photosynthetic rate at saturating irradiance and at ambient atmospheric CO2 concentration (Asat) measurements, from which Vcmax can be extracted using a ‘one-point method’.

  3. Quantifying the impact of decay in bed-net efficacy on malaria transmission

    SciTech Connect (OSTI)

    Ngonghala, Calistus N.; Del Valle, Sara Y.; Zhao, Ruijun; Mohammed-Awel, Jemal

    2014-08-23

    Insecticide-treated nets (ITNs) are at the forefront of malaria control programs and even though the percentage of households in sub-Saharan Africa that owned nets increased from 3% in 2000 to 53% in 2012, many children continue to die from malaria. The potential impact of ITNs on reducing malaria transmission is limited due to inconsistent or improper use, as well as physical decay in effectiveness. Most mathematical models for malaria transmission have assumed a fixed effectiveness rate for bed-nets, which can overestimate the impact of nets on malaria control. We develop a model for malaria spread that captures the decrease in ITN effectiveness due to physical and chemical decay, as well as human behavior as a function of time. We perform uncertainty and sensitivity analyses to identify and rank parameters that play a critical role in malaria transmission. These analyses show that the basic reproduction number R0, and the infectious human population are most sensitive to bed-net coverage and the biting rate of mosquitoes. Our results show the existence of a backward bifurcation for the case in which ITN efficacy is constant over time, which occurs for some range of parameters and is characterized by high malaria mortality in humans. This result implies that bringing R0 to less than one is not enough for malaria elimination but rather additional efforts will be necessary to control the disease. For the case in which ITN efficacy decays over time, we determine coverage levels required to control malaria for different ITN efficacies and demonstrate that ITNs with longer useful lifespans perform better in malaria control. We conclude that malaria control programs should focus on increasing bed-net coverage, which can be achieved by enhancing malaria education and increasing bed-net distribution in malaria endemic regions.

  4. Quantifying the impact of decay in bed-net efficacy on malaria transmission

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Ngonghala, Calistus N.; Del Valle, Sara Y.; Zhao, Ruijun; Mohammed-Awel, Jemal

    2014-08-23

    Insecticide-treated nets (ITNs) are at the forefront of malaria control programs and even though the percentage of households in sub-Saharan Africa that owned nets increased from 3% in 2000 to 53% in 2012, many children continue to die from malaria. The potential impact of ITNs on reducing malaria transmission is limited due to inconsistent or improper use, as well as physical decay in effectiveness. Most mathematical models for malaria transmission have assumed a fixed effectiveness rate for bed-nets, which can overestimate the impact of nets on malaria control. We develop a model for malaria spread that captures the decrease inmoreITN effectiveness due to physical and chemical decay, as well as human behavior as a function of time. We perform uncertainty and sensitivity analyses to identify and rank parameters that play a critical role in malaria transmission. These analyses show that the basic reproduction number R0, and the infectious human population are most sensitive to bed-net coverage and the biting rate of mosquitoes. Our results show the existence of a backward bifurcation for the case in which ITN efficacy is constant over time, which occurs for some range of parameters and is characterized by high malaria mortality in humans. This result implies that bringing R0 to less than one is not enough for malaria elimination but rather additional efforts will be necessary to control the disease. For the case in which ITN efficacy decays over time, we determine coverage levels required to control malaria for different ITN efficacies and demonstrate that ITNs with longer useful lifespans perform better in malaria control. We conclude that malaria control programs should focus on increasing bed-net coverage, which can be achieved by enhancing malaria education and increasing bed-net distribution in malaria endemic regions.less

  5. Political efficacy and familiarity as predictors of attitudes towards electric transmission lines in the United States

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Joe, Jeffrey C.; Hendrickson, Kelsie; Wong, Maria; Kane, Stephanie L.; Solan, David; Carlisle, Juliet E.; Koehler, David; Ames, Daniel P.; Beazer, Robert

    2016-05-18

    Public opposition to the construction (i.e., siting) of new high voltage overhead transmission lines is not a new or isolated phenomenon. Past research has posited a variety of reasons, applied general theories, and has provided empirical evidence to explain public opposition. The existing literature, while clarifying many elements of the issue, does not yet fully explain the complexities underlying this public opposition phenomenon. As a result, the current study demonstrated how two overlooked factors, people’s sense of political efficacy and their familiarity (i.e., prior exposure) with transmission lines, explained attitudes of support and opposition to siting new power lines.

  6. Strobe Light Deterrent Efficacy Test and Fish Behavior Determination at Grand Coulee Dam Third Powerplant Forebay

    SciTech Connect (OSTI)

    Johnson, Robert L. ); Simmons, Mary Ann ); Simmons, Carver S. ); McKinstry, Craig A. ); Cook, Chris B. ); Thorsten, Susan L. ); Lecaire, Richard; Francis, Stephen

    2003-01-29

    This report describes the work conducted during the second year of a multi-year study to assess the efficacy of a prototype strobe light system in eliciting a negative phototactic response in kokanee and rainbow trout. The strobe light system is being evaluated as a means to prevent entrainment (and subsequent loss) of fish at the entrance to the forebay adjacent to the third powerplant at Grand Coulee Dam. Pacific Northwest National Laboratory and the Confederated Tribes of the Colville Reservation are collaborating on the three-year study being conducted for the Bonneville Power Administration and the Northwest Power Planning Council.

  7. Efficacy and Safety of a Novel Vascular Closure Device (Glubran 2 Seal) After Diagnostic and Interventional Angiography in Patients with Peripheral Arterial Occlusive Disease

    SciTech Connect (OSTI)

    Del Corso, Andrea; Bargellini, Irene Cicorelli, Antonio; Perrone, Orsola; Leo, Michele; Lunardi, Alessandro; Alberti, Aldo; Tomei, Francesca; Cioni, Roberto; Ferrari, Mauro; Bartolozzi, Carlo

    2013-04-15

    To prospectively evaluate safety and efficacy of a novel vascular closure device (Glubran 2 Seal) after peripheral angiography in patients with peripheral arterial occlusive disease (PAOD). From December 2010 to June 2011, all consecutive patients with PAOD undergoing peripheral angiography were prospectively enrolled onto the study after percutaneous antegrade or retrograde puncture of the common femoral artery. After angiography, the Glubran 2 Seal device was used to achieve hemostasis. The following data were registered: technical success and manual compression duration, patients' discomfort (scale 0-5), operators' technical difficulty (scale 0-5), and vascular complications. The site of hemostasis was evaluated by clinical inspection and color-coded Duplex ultrasound performed 1 day and 1 month after the procedure. One hundred seventy-eight patients were enrolled (112 male, mean age 70.8 years) with a total of 206 puncture sites, including 104 (50.5 %) antegrade accesses. The device was successful in 198(96.1 %) of 206 procedures, with 8 cases of manual compression lasting longer than 5 min (maximum 20 min). No major vascular complications were observed, resulting in 100 % procedural success. Minor complications occurred in seven procedures (3.4 %), including two cases of pseudoaneurysms, successfully treated by ultrasound-guided glue injection. The mean {+-} standard deviation score for patients' discomfort was 0.9 {+-} 0.7, whereas the mean score for operators' difficulty was 1.2 {+-} 0.9. In patients with PAOD, the Glubran 2 Seal represents a simple, painless, and efficient vascular closure device, able to achieve hemostasis both in antegrade and retrograde accesses.

  8. Chronomodulation of topotecan or X-radiation treatment increases treatment efficacy without enhancing acute toxicity

    SciTech Connect (OSTI)

    Mullins, Dana; Proulx, Denise; Saoudi, A.; Ng, Cheng E. . E-mail: cng@ohri.ca

    2005-05-01

    Purpose: Topotecan (TPT), a camptothecin analog, is currently used to treat human ovarian and small-cell lung cancer and is in clinical trials for other tumor sites. However, it is unknown whether chronomodulation of TPT treatment is beneficial. We examined the effects of administering TPT or X-radiation (XR) alone at different times of the day or night. Methods: We treated mice bearing human colorectal tumor xenografts at four different times representing the early rest period (9 AM or 3 HALO [hours after light onset]), late rest period (3 PM or 9 HALO), early active period (9 PM or 15 HALO), and late active period (3 AM or 21 HALO) of the mice. We gave either TPT (12 mg/kg, injected i.p.) or XR (4 Gy, directed to the tumor) twice weekly on Days 0, 4, 7, 10 within 2 weeks. Results: Treatment with either TPT or XR at 3 AM demonstrated the greatest efficacy (measured by a tumor regrowth assay) without significantly increasing acute toxicity (assessed by a decrease in leukocyte counts or body weight). Conversely, treatment at 3 PM, in particular, showed increased toxicity without any enhanced efficacy. Conclusions: Our study provided the first evidence that chronomodulation of TPT treatments, consistent with the findings of other camptothecin analogs, is potentially clinically beneficial. Additionally, our findings suggest that chronomodulation of fractionated XR treatments is also potentially clinically beneficial.

  9. Depth of maximum of air-shower profiles at the Pierre Auger Observatory. I. Measurements at energies above $$10^{17.8}$$ eV

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Aab, Alexander

    2014-12-31

    We report a study of the distributions of the depth of maximum, Xmax, of extensive air-shower profiles with energies above 1017.8 eV as observed with the fluorescence telescopes of the Pierre Auger Observatory. The analysis method for selecting a data sample with minimal sampling bias is described in detail as well as the experimental cross-checks and systematic uncertainties. Furthermore, we discuss the detector acceptance and the resolution of the Xmax measurement and provide parametrizations thereof as a function of energy. Finally, the energy dependence of the mean and standard deviation of the Xmax distributions are compared to air-shower simulations formore » different nuclear primaries and interpreted in terms of the mean and variance of the logarithmic mass distribution at the top of the atmosphere.« less

  10. SU-E-T-174: Evaluation of the Optimal Intensity Modulated Radiation Therapy Plans Done On the Maximum and Average Intensity Projection CTs

    SciTech Connect (OSTI)

    Jurkovic, I; Stathakis, S; Li, Y; Patel, A; Vincent, J; Papanikolaou, N; Mavroidis, P

    2014-06-01

    Purpose: To determine the difference in coverage between plans done on average intensity projection and maximum intensity projection CT data sets for lung patients and to establish correlations between different factors influencing the coverage. Methods: For six lung cancer patients, 10 phases of equal duration through the respiratory cycle, the maximum and average intensity projections (MIP and AIP) from their 4DCT datasets were obtained. MIP and AIP datasets had three GTVs delineated (GTVaip — delineated on AIP, GTVmip — delineated on MIP and GTVfus — delineated on each of the 10 phases and summed up). From the each GTV, planning target volumes (PTV) were then created by adding additional margins. For each of the PTVs an IMRT plan was developed on the AIP dataset. The plans were then copied to the MIP data set and were recalculated. Results: The effective depths in AIP cases were significantly smaller than in MIP (p < 0.001). The Pearson correlation coefficient of r = 0.839 indicates strong degree of positive linear relationship between the average percentage difference in effective depths and average PTV coverage on the MIP data set. The V2 0 Gy of involved lung depends on the PTV coverage. The relationship between PTVaip mean CT number difference and PTVaip coverage on MIP data set gives r = 0.830. When the plans are produced on MIP and copied to AIP, r equals −0.756. Conclusion: The correlation between the AIP and MIP data sets indicates that the selection of the data set for developing the treatment plan affects the final outcome (cases with high average percentage difference in effective depths between AIP and MIP should be calculated on AIP). The percentage of the lung volume receiving higher dose depends on how well PTV is covered, regardless of on which set plan is done.

  11. Enhancement of the anti-damping spin torque efficacy of platinum by interface modification

    SciTech Connect (OSTI)

    Nguyen, Minh-Hai; Pai, Chi-Feng; Nguyen, Kayla X.; Buhrman, R. A.; Muller, David A.; Ralph, D. C.

    2015-06-01

    We report a strong enhancement of the efficacy of the spin Hall effect (SHE) of Pt for exerting anti-damping spin torque on an adjacent ferromagnetic layer by the insertion of ≈0.5 nm layer of Hf between a Pt film and a thin, ≤2 nm, Fe{sub 60}Co{sub 20}B{sub 20} ferromagnetic layer. This enhancement is quantified by measurement of the switching current density when the ferromagnetic layer is the free electrode in a magnetic tunnel junction. The results are explained as the suppression of spin pumping through a substantial decrease in the effective spin-mixing conductance of the interface, but without a concomitant reduction of the ferromagnet's absorption of the SHE generated spin current.

  12. Petroleum production at Maximum Efficient Rate Naval Petroleum Reserve No. 1 (Elk Hills), Kern County, California. Final Supplemental Environmental Impact Statement

    SciTech Connect (OSTI)

    Not Available

    1993-07-01

    This document provides an analysis of the potential impacts associated with the proposed action, which is continued operation of Naval Petroleum Reserve No. I (NPR-1) at the Maximum Efficient Rate (MER) as authorized by Public law 94-258, the Naval Petroleum Reserves Production Act of 1976 (Act). The document also provides a similar analysis of alternatives to the proposed action, which also involve continued operations, but under lower development scenarios and lower rates of production. NPR-1 is a large oil and gas field jointly owned and operated by the federal government and Chevron U.SA Inc. (CUSA) pursuant to a Unit Plan Contract that became effective in 1944; the government`s interest is approximately 78% and CUSA`s interest is approximately 22%. The government`s interest is under the jurisdiction of the United States Department of Energy (DOE). The facility is approximately 17,409 acres (74 square miles), and it is located in Kern County, California, about 25 miles southwest of Bakersfield and 100 miles north of Los Angeles in the south central portion of the state. The environmental analysis presented herein is a supplement to the NPR-1 Final Environmental Impact Statement of that was issued by DOE in 1979 (1979 EIS). As such, this document is a Supplemental Environmental Impact Statement (SEIS).

  13. Relaxation and critical strain for maximum In incorporation in AlInGaN on GaN grown by metal organic vapour phase epitaxy

    SciTech Connect (OSTI)

    Reuters, Benjamin; Finken, M.; Wille, A.; Kalisch, H.; Vescan, A.; Hollaender, B.; Heuken, M.

    2012-11-01

    Quaternary AlInGaN layers were grown on conventional GaN buffer layers on sapphire by metal organic vapour phase epitaxy at different surface temperatures and different reactor pressures with constant precursor flow conditions. A wide range in compositions within 30-62% Al, 5-29% In, and 23-53% Ga was covered, which leads to different strain states from high tensile to high compressive. From high-resolution x-ray diffraction and Rutherford backscattering spectrometry, we determined the compositions, strain states, and crystal quality of the AlInGaN layers. Atomic force microscopy measurements were performed to characterize the surface morphology. A critical strain value for maximum In incorporation near the AlInGaN/GaN interface is presented. For compressively strained layers, In incorporation is limited at the interface as residual strain cannot exceed an empirical critical value of about 1.1%. Relaxation occurs at about 15 nm thickness accompanied by strong In pulling. Tensile strained layers can be grown pseudomorphically up to 70 nm at a strain state of 0.96%. A model for relaxation in compressively strained AlInGaN with virtual discrete sub-layers, which illustrates the gradually changing lattice constant during stress reduction is presented.

  14. Biochemical bases for the biogeography of C3/C4 grasses and implications for changing distributions since the last glacial maximum

    SciTech Connect (OSTI)

    Collatz, G.J.; Berry, J.A.

    1995-06-01

    Differential distributions of C3 and C4 grass taxa correlate with geographic and climatic factors. A simple model based on the temperature dependence of the photosynthetic quantum yield of C3 plants and the lack of response of the C4 quantum yield to temperature is used to predict the global distribution of C4 grasses at current atmospheric CO2 concentrations and climate. The model predicts a cross over temperature at which the quantum yield responses intersect; at temperatures above the cross over point C4 grasses are favored over C3. The cross over temperature is about 22{degrees}C at current atmospheric CO2 concentrations. Using this criterion an accurate 1x1 degree map of C4 grass dominance over C3 grasses is produced from climatological mean monthly temperatures. Accuracy is improved by considering the co-occurrence of sufficient rainfall for growth during the months warm enough for C4 dominance. Rising temperatures and CO2 concentrations since the last glacial maximum (LGM) are expected to have an impact on past C4 grass distributions. We have used climate generated by the NCAR CCM to predict the extent of climatic regions favoring C4 over C3 since the LGM. Though low temperatures favor C3 photosynthesis, the low CO2 concentrations in the past more than off-set this effect. The extent of C4 favorable climates are predicted to have been greater during the LGM and have shrunk since then. The model does not take into account important biotic factors such as competition for light and herbivory or abiotic factors such as fire frequency that can affect the dominance of grasslands over other vegetation types.

  15. Assessing the Efficacy of the Aerobic Methanotrophic Biofilter in Methane Hydrate Environments

    SciTech Connect (OSTI)

    Valentine, David

    2012-09-30

    In October 2008 the University of California at Santa Barbara (UCSB) initiated investigations of water column methane oxidation in methane hydrate environments, through a project funded by the National Energy Technology Laboratory (NETL) entitled: assessing the efficacy of the aerobic methanotrophic biofilter in methane hydrate environments. This Final Report describes the scientific advances and discoveries made under this award as well as the importance of these discoveries in the broader context of the research area. Benthic microbial mats inhabit the sea floor in areas where reduced chemicals such as sulfide reach the more oxidizing water that overlies the sediment. We set out to investigate the role that methanotrophs play in such mats at locations where methane reaches the sea floor along with sulfide. Mats were sampled from several seep environments and multiple sets were grown in-situ at a hydrocarbon seep in the Santa Barbara Basin. Mats grown in-situ were returned to the laboratory and used to perform stable isotope probing experiments in which they were treated with 13C-enriched methane. The microbial community was analyzed, demonstrating that three or more microbial groups became enriched in methane?s carbon: methanotrophs that presumably utilize methane directly, methylotrophs that presumably consume methanol excreted by the methanotrophs, and sulfide oxidizers that presumably consume carbon dioxide released by the methanotrophs and methylotrophs. Methanotrophs reached high relative abundance in mats grown on methane, but other bacterial processes include sulfide oxidation appeared to dominate mats, indicating that methanotrophy is not a dominant process in sustaining these benthic mats, but rather a secondary function modulated by methane availability. Methane that escapes the sediment in the deep ocean typically dissolved into the overlying water where it is available to methanotrophic bacteria. We set out to better understand the efficacy of this

  16. Setting the renormalization scale in pQCD: Comparisons of the principle of maximum conformality with the sequential extended Brodsky-Lepage-Mackenzie approach

    SciTech Connect (OSTI)

    Ma, Hong -Hao; Wu, Xing -Gang; Ma, Yang; Brodsky, Stanley J.; Mojaza, Matin

    2015-05-26

    A key problem in making precise perturbative QCD (pQCD) predictions is how to set the renormalization scale of the running coupling unambiguously at each finite order. The elimination of the uncertainty in setting the renormalization scale in pQCD will greatly increase the precision of collider tests of the Standard Model and the sensitivity to new phenomena. Renormalization group invariance requires that predictions for observables must also be independent on the choice of the renormalization scheme. The well-known Brodsky-Lepage-Mackenzie (BLM) approach cannot be easily extended beyond next-to-next-to-leading order of pQCD. Several suggestions have been proposed to extend the BLM approach to all orders. In this paper we discuss two distinct methods. One is based on the Principle of Maximum Conformality (PMC), which provides a systematic all-orders method to eliminate the scale and scheme ambiguities of pQCD. The PMC extends the BLM procedure to all orders using renormalization group methods; as an outcome, it significantly improves the pQCD convergence by eliminating renormalon divergences. An alternative method is the sequential extended BLM (seBLM) approach, which has been primarily designed to improve the convergence of pQCD series. The seBLM, as originally proposed, introduces auxiliary fields and follows the pattern of the ?0-expansion to fix the renormalization scale. However, the seBLM requires a recomputation of pQCD amplitudes including the auxiliary fields; due to the limited availability of calculations using these auxiliary fields, the seBLM has only been applied to a few processes at low orders. In order to avoid the complications of adding extra fields, we propose a modified version of seBLM which allows us to apply this method to higher orders. As a result, we then perform detailed numerical comparisons of the two alternative scale-setting approaches by investigating their predictions for the annihilation cross section ratio R

  17. Development and Performance of Detectors for the Cryogenic Dark Matter Search Experiment with an Increased Sensitivity Based on a Maximum Likelihood Analysis of Beta Contamination

    SciTech Connect (OSTI)

    Driscoll, Donald D.; /Case Western Reserve U.

    2004-01-01

    first use of a beta-eliminating cut based on a maximum-likelihood characterization described above.

  18. Improvement of Stent Retriever Design and Efficacy of Mechanical Thrombectomy in a Flow Model

    SciTech Connect (OSTI)

    Wenger, Katharina; Nagl, Frank; Wagner, Marlies Berkefeld, Joachim

    2013-02-15

    In vitro experiments were performed to evaluate the efficacy of mechanical intracranial thrombectomy comparing the newly developed Aperio stent retriever and standard devices for stroke treatment. The Aperio (A), with an increased working length of 4 cm and a special cell design for capturing and withholding clots, was compared to three benchmark devices: the Solitaire retrievable stent (B), the Merci X6 (C), and the Merci L5 retriever (D). In a vascular glass model with pulsatile flow, reminiscent of the M1 segment of the middle cerebral artery, we repeatedly induced occlusion by generating thrombi via a modified Chandler loop system. The numbers of recanalization attempts, peripheral embolizations, and recanalizations at the site of occlusion were recorded during 10 retrieval experiments with each device. Eleven devices were able to remove the blood clots from the occluded branch. In 34 of 40 experiments, restoration of flow was obtained in 1-3 attempts. The main differences between the study devices were observed in terms of clot withholding and fragmentation during retrieval. Although there was only one fragmentation recorded for device A, disengagement of the whole clot or peripheral embolization of fragments occurred more frequently (5-7 times) with devices B, C, and D. In a vascular model, the design of device A was best at capturing and withholding thrombi during retrieval. Further study will be necessary to see whether this holds true in clinical applications.

  19. A miniature mimic of host defense peptides with systemic antibacterial efficacy

    SciTech Connect (OSTI)

    Sarig, Hadar; Livne, Liran; Held-Kuznetsov, Victoria; Zaknoon, Fadia; Ivankin, Andrey; Gidalevitz, David; Mor, Amram

    2010-08-23

    Oligomers of acylated lysines (OAKs) are synthetic mimics of host defense peptides (HDPs) with promising antimicrobial properties. Here we challenged the OAK concept for its ability to generate both systemically efficient and economically viable lead compounds for fighting multidrug-resistant bacteria. We describe the design and characterization of a miniature OAK composed of only 3 lysyls and 2 acyls (designated C{sub 12({omega}7)}K-{beta}{sub 12}) that preferentially targets gram-positive species by a bacteriostatic mode of action. To gain insight into the mechanism of action, we examined the interaction of OAK with various potential targets, including phospholipid bilayers, using surface plasmon resonance, and Langmuir monolayers, using insertion assays, epifluorescence microscopy, and grazing incidence X-ray diffraction, in a complementary manner. Collectively, the data support the notion that C{sub 12({omega}7)}K-{beta}{sub 12} damages the plasma-membrane architecture similarly to HDPs, that is, following a near-classic 2-step interaction including high-affinity electrostatic adhesion and a subsequent shallow insertion that was limited to the phospholipid head group region. Notably, preliminary acute toxicity and efficacy studies performed with mouse models of infection have consolidated the potential of OAK for treating bacterial infections, including systemic treatments of methicillin-resistant Staphylococcus aureus. Such simple yet robust chemicals might be useful for various antibacterial applications while circumventing potential adverse effects associated with cytolytic compounds.

  20. STUDYING LARGE- AND SMALL-SCALE ENVIRONMENTS OF ULTRAVIOLET LUMINOUS

    Office of Scientific and Technical Information (OSTI)

    CA 91101 (United States); Neff, Susan G. Laboratory for Astronomy and Solar Physics, NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States), E-mail:...

  1. HIGH-DENSITY CIRCUMSTELLAR INTERACTION IN THE LUMINOUS TYPE IIn...

    Office of Scientific and Technical Information (OSTI)

    ... University of Virginia, P.O. Box 400325, Charlottesville, VA 22904 (United States) CASA, University of Colorado, 593UCB Boulder, CO 80309-0593 (United States) Steward ...

  2. Distribution of dark and luminous mass in galaxies

    SciTech Connect (OSTI)

    Lovas, Stephen; Kielkopf, John F.

    2014-06-01

    A uniform scale relation between dark and baryonic matter is observed in galaxies over a broad range of physical parameter space. The ratio of dark to baryonic mass is found to increase proportionately with radial distance in observational data spanning a wide dynamic range of morphological type, rotation velocity, radius, surface density, and mass. This close relation between dark and baryonic mass poses a fine-tuning problem for galaxy formation models. Such a uniform scale relation, extending from the inner galactic region to the outermost kinematic data point, may play a role in clarifying the dark matter phenomenon.

  3. STUDYING LARGE- AND SMALL-SCALE ENVIRONMENTS OF ULTRAVIOLET LUMINOUS...

    Office of Scientific and Technical Information (OSTI)

    MD 21218 (United States) Laboratoire d'Astrophysique de Marseille, BP8, Traverse du Siphon, F-13376 Marseille (France) Center for Space Astrophysics, Yonsei University, Seoul...

  4. Topical efficacy of dimercapto-chelating agents against lewisite-induced skin lesions in SKH-1 hairless mice

    SciTech Connect (OSTI)

    Mouret, Stéphane; Wartelle, Julien; Emorine, Sandy; Bertoni, Marine; Nguon, Nina; Cléry-Barraud, Cécile; Dorandeu, Frédéric; Boudry, Isabelle

    2013-10-15

    Lewisite is a potent chemical warfare arsenical vesicant that can cause severe skin lesions. Today, lewisite exposure remains possible during demilitarization of old ammunitions and as a result of deliberate use. Although its cutaneous toxicity is not fully elucidated, a specific antidote exists, the British anti-lewisite (BAL, dimercaprol) but it is not without untoward effects. Analogs of BAL, less toxic, have been developed such as meso-2,3-dimercaptosuccinic acid (DMSA) and have been employed for the treatment of heavy metal poisoning. However, efficacy of DMSA against lewisite-induced skin lesions remains to be determined in comparison with BAL. We have thus evaluated in this study the therapeutic efficacy of BAL and DMSA in two administration modes against skin lesions induced by lewisite vapor on SKH-1 hairless mice. Our data demonstrate a strong protective efficacy of topical application of dimercapto-chelating agents in contrast to a subcutaneous administration 1 h after lewisite exposure, with attenuation of wound size, necrosis and impairment of skin barrier function. The histological evaluation also confirms the efficacy of topical application by showing that treatments were effective in reversing lewisite-induced neutrophil infiltration. This protective effect was associated with an epidermal hyperplasia. However, for all the parameters studied, BAL was more effective than DMSA in reducing lewisite-induced skin injury. Together, these findings support the use of a topical form of dimercaprol-chelating agent against lewisite-induced skin lesion within the first hour after exposure to increase the therapeutic management and that BAL, despite its side-effects, should not be abandoned. - Highlights: • Topically applied dimercapto-chelating agents reduce lewisite-induced skin damage. • One topical application of BAL or DMSA is sufficient to reverse lewisite effects. • Topical BAL is more effective than DMSA to counteract lewisite-induced skin damage.

  5. Pre- and post-exposure safety and efficacy of attenuated rabies virus vaccines are enhanced by their expression of IFNγ

    SciTech Connect (OSTI)

    Barkhouse, Darryll A.; Faber, Milosz; Hooper, D. Craig

    2015-01-01

    Consistent with evidence of a strong correlation between interferon gamma (IFNγ) production and rabies virus (RABV) clearance from the CNS, we recently demonstrated that engineering a pathogenic RABV to express IFNγ highly attenuates the virus. Reasoning that IFNγ expression by RABV vaccines would enhance their safety and efficacy, we reverse-engineered two proven vaccine vectors, GAS and GASGAS, to express murine IFNγ. Mortality and morbidity were monitored during suckling mice infection, immunize/challenge experiments and mixed intracranial infections. We demonstrate that GASγ and GASγGAS are significantly attenuated in suckling mice compared to the GASGAS vaccine. GASγ better protects mice from lethal DRV4 RABV infection in both pre- and post-exposure experiments compared to GASGAS. Finally, GASγGAS reduces post-infection neurological sequelae, compared to control, during mixed intracranial infection with DRV4. These data show IFNγ expression by a vaccine vector can enhance its safety while increasing its efficacy as pre- and post-exposure treatment. - Highlights: • IFNγ expression improves attenuated rabies virus safety and immunogenicity. • IFNγ expression is safer and more immunogenic than doubling glycoprotein expression. • Co-infection with IFNγ-expressing RABV prevents wild-type rabies virus lethality. • Vaccine safety and efficacy is additive for IFNγ and double glycoprotein expression.

  6. Efficacy of Aerosol-Cloud Interactions Under Varying Meteorological Conditions: Southern Great Plains Vs. Pt. Reyes

    SciTech Connect (OSTI)

    Dunn, M.; Schwartz, S.; Kim, B.-G.; Miller, M.; Liu, Y.; Min, Q.

    2008-03-10

    Several studies have demonstrated that cloud dynamical processes such as entrainment mixing may be the primary modulator of cloud optical properties in certain situations. For example, entrainment of dry air alters the cloud drop size distribution by enhancing drop evaporation. However, the effect of entrainment mixing and other forms or turbulence is still quite uncertain. Although these factors and aerosol-cloud interactions should be considered together when evaluating the efficacy of aerosol indirect effects, the underlying mechanisms appear to be dependent upon each other. In addition, accounting for them is impossible with the current understanding of aerosol indirect effect. Therefore, careful objective screening and analysis of observations are needed to determine the extent to which mixing related properties affect cloud optical properties, apart from the aerosol first indirect effect. This study addresses the role of aerosol-cloud interactions in the context of varying meteorological conditions based on ARM data obtained at the Southern Great Plains (SGP) site in Oklahoma and at Pt. Reyes, California. Previous analyses of the continental stratiform clouds at the SGP site have shown that the thicker clouds of high liquid water path (LWP) tend to contain sub adiabatic LWPs. These sub adiabatic LWPs, which result from active mixing processes, correspond to a lower susceptibility of the clouds to aerosol-cloud interactions, and, hence, to reduced aerosol indirect effects. In contrast, the consistently steady and thin maritime stratus clouds observed at Pt. Reyes are much closer to adiabatic. These clouds provide an excellent benchmark for the study of the aerosol influence on modified marine clouds relative to continental clouds, since they form in a much more homogeneous meteorological environment than those at the continental site.

  7. Efficacy and Safety of Transarterial Radioembolization Versus Chemoembolization in Patients With Hepatocellular Carcinoma

    SciTech Connect (OSTI)

    Moreno-Luna, Laura E., E-mail: morenoluna.laura@gmail.com; Yang, Ju Dong; Sanchez, William [College of Medicine, Mayo Clinic, Division of Gastroenterology and Hepatology (United States); Paz-Fumagalli, Ricardo [College of Medicine, Mayo Clinic, Department of Radiology (United States); Harnois, Denise M.; Mettler, Teresa A. [College of Medicine, Mayo Clinic, Division of Gastroenterology and Hepatology (United States); Gansen, Denise N. [College of Medicine, Mayo Clinic, Department of Radiology (United States); Groen, Piet C. de; Lazaridis, Konstantinos N.; Narayanan Menon, K. V.; LaRusso, Nicholas F. [College of Medicine, Mayo Clinic, Division of Gastroenterology and Hepatology (United States); Alberts, Steven R. [College of Medicine, Mayo Clinic and Mayo Clinic Cancer Center, Department of Oncology (United States); Gores, Gregory J. [College of Medicine, Mayo Clinic, Division of Gastroenterology and Hepatology (United States); Fleming, Chad J. [College of Medicine, Mayo Clinic, Department of Radiology (United States); Slettedahl, Seth W.; Harmsen, William S.; Therneau, Terry M. [College of Medicine, Mayo Clinic, Department of Health Sciences Research (United States); Wiseman, Gregory A.; Andrews, James C. [College of Medicine, Mayo Clinic, Department of Radiology (United States); Roberts, Lewis R., E-mail: roberts.lewis@mayo.edu [College of Medicine, Mayo Clinic, Division of Gastroenterology and Hepatology (United States)

    2013-06-15

    Purpose. Intermediate-stage hepatocellular carcinoma (HCC) is usually treated with locoregional therapy using transarterial chemoembolization (TACE). Transarterial radioembolization (TARE) using {beta}-emitting yttrium-90 integral to the glass matrix of the microspheres is an alternative to TACE. This retrospective case-control study compared the outcomes and safety of TARE versus TACE in patients with unresectable HCC. Materials and Methods. Patients with unresectable HCC without portal vein thrombosis treated with TARE between 2005 and 2008 (n = 61) were retrospectively frequency-matched by age, sex, and liver dysfunction with TACE-treated patients (n = 55) in the Mayo Clinic Hepatobiliary Neoplasia Registry. Imaging studies were reviewed, and clinical and safety outcomes were abstracted from the medical records. Results. Complete tumor response was more common after TARE (12 %) than after TACE (4 %) (p = 0.17). When complete response was combined with partial response and stable disease, there was no difference between TARE and TACE. Median survival did not differ between the two groups (15.0 months for TARE and 14.4 months for TACE; p = 0.47). Two-year survival rates were 30 % for TARE and 24 % for TACE. TARE patients received fewer treatments (p < 0.001). Fifty-nine (97 %) TARE patients received outpatient treatment. In contrast, 53 (98 %) TACE patients were hospitalized for {>=}1 day (p < 0.001). Compared with TACE, TARE was more likely to induce fatigue (p = 0.003) but less likely to cause fever (p = 0.02). Conclusion. There was no significant difference in efficacy between TARE and TACE. TARE patients reported more fatigue but had less fever than TACE patients. Treatment with TARE required less hospitalization than treatment with TACE. These findings require confirmation in randomized trials.

  8. The Efficacy of Ultraviolet Radiation for Sterilizing Tools Used for Surgically Implanting Transmitters into Fish

    SciTech Connect (OSTI)

    Walker, Ricardo W.; Markillie, Lye Meng; Colotelo, Alison HA; Gay, Marybeth E.; Woodley, Christa M.; Brown, Richard S.

    2013-02-28

    Telemetry is frequently used to examine the behavior of fish, and the transmitters used are normally surgically implanted into the coelom of fish. Implantation requires the use of surgical tools such as scalpels, forceps, needle holders, and sutures. When several fish are implanted consecutively for large telemetry studies, it is common for surgical tools to be sterilized or, at minimum, disinfected between each use so that pathogens that may be present are not spread among fish. However, autoclaving tools can take a long period of time, and chemical sterilants or disinfectants can be harmful to both humans and fish and have varied effectiveness. Ultraviolet (UV) radiation is commonly used to disinfect water in aquaculture facilities. However, this technology has not been widely used to sterilize tools for surgical implantation of transmitters in fish. To determine its efficacy for this application, Pacific Northwest National Laboratory researchers used UV radiation to disinfect surgical tools (i.e., forceps, needle holder, stab scalpel, and suture) that were exposed to one of four aquatic organisms that typically lead to negative health issues for salmonids. These organisms included Aeromonas salmonicida, Flavobacterium psychrophilum, Renibacterium salmoninarum, and Saprolegnia parasitica. Surgical tools were exposed to the bacteria by dipping them into a confluent suspension of three varying concentrations (i.e., low, medium, high). After exposure to the bacterial culture, tools were placed into a mobile Millipore UV sterilization apparatus. The tools were then exposed for three different time periods—2, 5, or 15 min. S. parasitica, a water mold, was tested using an agar plate method and forceps-pinch method. UV light exposures of 5 and 15 min were effective at killing all four organisms. UV light was also effective at killing Geobacillus stearothermophilus, the organism used as a biological indicator to verify effectiveness of steam sterilizers. These

  9. Measured Off-Grid LED Lighting System Performance

    SciTech Connect (OSTI)

    Granderson, Jessica; Galvin, James; Bolotov, Dmitriy; Clear, Robert; Jacobson, Arne; Mills, Evan

    2008-12-18

    This report is a product of our ongoing effort to support the development of high-quality yet affordable products for off-grid lighting in the developing world that have good potential to succeed in the market. The effort includes work to develop low-cost testing procedures, to identify useful performance metrics, and to facilitate the development of industry standards and product rating protocols. We conducted laboratory testing of nine distinct product lines. In some cases we also tested multiple generations of a single product line and/or operating modes for a product. The resultsare summarized in Table 1. We found that power consumption and light output varied by nearly a factor of 12, with efficacy varying by a factor of more than six. Of particular note, overall luminous efficacy varied from 8.2 to 53.1 lumens per watt. Color quality indices variedmaterially, especially for correlated color temperature. Maximum illuminance, beamcandlepower, and luminance varied by 8x, 32x, and 61x respectively, suggesting considerable differences among products in terms of service levels and visual comfort. Glare varied by1.4x, and was above acceptable thresholds in most cases. Optical losses play a role in overall performance, varying by a factor of 3.2 and ranging as high as 24percent. These findings collectively indicate considerable potential for improved product design.

  10. Lumileds Develops High-Voltage LED Light Engine with Integrated Driver

    Broader source: Energy.gov [DOE]

    With the help of DOE funding, Lumileds has developed a high-voltage LED light engine with an integrated driver, achieving an efficacy greater than 128 lm/W at a luminous flux greater than 4,100 lm...

  11. Efficacy of chitosan and other natural polymers in removing COD, TSS, heavy metals and pahs from municipal wastewater at Deer Island, Massachusetts. Technical report

    SciTech Connect (OSTI)

    Murcott, S.; Harleman, D.R.F.

    1992-10-01

    A series of tests was conducted at the Deer Island Primary Treatment Plant during the spring and summer of 1992 to determine the efficacy of chitosan and other natural polymers as coagulants, coagulant aids and flocculents in wastewater treatment. Prior to this undertaking, as part of the MIT Investigation of Chemically Enhanced Primary Treatment at the MWRA Project, the efficacy of metal salts and synthetic polymers had been studied at Deer Island. Those tests provided the standard against which to measure the viability of natural polymer use in municipal wastewater treatment. The major conclusions of the chitosan and other natural polymers study for Deer Island wastewater are included.

  12. Speech processing using maximum likelihood continuity mapping

    DOE Patents [OSTI]

    Hogden, John E.

    2000-01-01

    Speech processing is obtained that, given a probabilistic mapping between static speech sounds and pseudo-articulator positions, allows sequences of speech sounds to be mapped to smooth sequences of pseudo-articulator positions. In addition, a method for learning a probabilistic mapping between static speech sounds and pseudo-articulator position is described. The method for learning the mapping between static speech sounds and pseudo-articulator position uses a set of training data composed only of speech sounds. The said speech processing can be applied to various speech analysis tasks, including speech recognition, speaker recognition, speech coding, speech synthesis, and voice mimicry.

  13. Maximum entropy models of ecosystem functioning

    SciTech Connect (OSTI)

    Bertram, Jason

    2014-12-05

    Using organism-level traits to deduce community-level relationships is a fundamental problem in theoretical ecology. This problem parallels the physical one of using particle properties to deduce macroscopic thermodynamic laws, which was successfully achieved with the development of statistical physics. Drawing on this parallel, theoretical ecologists from Lotka onwards have attempted to construct statistical mechanistic theories of ecosystem functioning. Jaynes’ broader interpretation of statistical mechanics, which hinges on the entropy maximisation algorithm (MaxEnt), is of central importance here because the classical foundations of statistical physics do not have clear ecological analogues (e.g. phase space, dynamical invariants). However, models based on the information theoretic interpretation of MaxEnt are difficult to interpret ecologically. Here I give a broad discussion of statistical mechanical models of ecosystem functioning and the application of MaxEnt in these models. Emphasising the sample frequency interpretation of MaxEnt, I show that MaxEnt can be used to construct models of ecosystem functioning which are statistical mechanical in the traditional sense using a savanna plant ecology model as an example.

  14. Efficacy of low level electric current (A-C) for controlling quagga mussles in the Welland Canal

    SciTech Connect (OSTI)

    Fears, C.; Mackie, G.L.

    1995-06-01

    The efficacy of systems (for which patents are pending) which use low-voltage A-C currents for preventing settlement and attachment by zebra mussels were tested with steel rods and plates placed near the intake of a pulp and paper plant in the Welland Canal at Thorold, Ontario. Six racks made of 16 ft. (4.9 m), 2x4s (5.1 x 10.2 cm) were placed into the Welland Canal on August 5, 1994. One rack had 1/8th in (3.2 mm) diam x 12 in (30.5 cm) long steel rods, each separated by 2 in (5.1 cm) attached to pressure treated wood and concrete blocks and an A-C current of 16 v (or 8 v/in); rack 2 had steel rods of the same configuration but 12 v (or 6 v/in) was applied; rack 3 was identical to these but no current was applied and was used as a rod control. The remaining three racks had steel plates, each plate being 3 in (7.6 cm) wide X 24 in (61 cm) long X 1/4 in (6.4 mm) thick and separated by 2 in (5.1 cm); one had 12 v applied (or 6 v/in), another had 16 v applied (or 8 v/in), and the third had no current and was used as a plate control. The racks were placed on the upstream and downstream side of the intake at a depth of about 7 ft (2.1 m) where the mussels populations were heaviest (as determined by SCUBA diving). All mussels were quagga mussels (Dreissena bugensis). The racks were pulled in mid November after settlement was complete and the results showed: (1) complete prevention of settlement of both new recruits and translocators at 8 volts/in with steel rods on both wood and concrete surfaces and with steel plate trash bars; (2) partial prevention of settlement at 6 volts/in with steel rods on both wood and concrete surfaces and steel plates; and (3) that, at current kilowatt hr rates, total efficacy at 8 volts/in would cost approximately $10.80/day/1000 sq ft using rods to protect concrete walls and about $16.32/day/1000 sq ft to protect 3 in wide x 1/4 in thick trash bars. These costs can be reduced even further with pulse dosed AC currents.

  15. Nevada Test Site probable maximum flood study, part of US Geological Survey flood potential and debris hazard study, Yucca Mountain Site for US Department of Energy, Office of Civilian Radioactive Waste Management

    SciTech Connect (OSTI)

    Bullard, K.L.

    1994-08-01

    The US Geological Survey (USGS), as part of the Yucca Mountain Project (YMP), is conducting studies at Yucca Mountain, Nevada. The purposes of these studies are to provide hydrologic and geologic information to evaluate the suitability of Yucca Mountain for development as a high-level nuclear waste repository, and to evaluate the ability of the mined geologic disposal system (MGDS) to isolate the waste in compliance with regulatory requirements. In particular, the project is designed to acquire information necessary for the Department of Energy (DOE) to demonstrate in its environmental impact statement (EIS) and license application whether the MGDS will meet the requirements of federal regulations 10 CFR Part 60, 10 CFR Part 960, and 40 CFR Part 191. Complete study plans for this part of the project were prepared by the USGS and approved by the DOE in August and September of 1990. The US Bureau of Reclamation (Reclamation) was selected by the USGS as a contractor to provide probable maximum flood (PMF) magnitudes and associated inundation maps for preliminary engineering design of the surface facilities at Yucca Mountain. These PMF peak flow estimates are necessary for successful waste repository design and construction. The PMF technique was chosen for two reasons: (1) this technique complies with ANSI requirements that PMF technology be used in the design of nuclear related facilities (ANSI/ANS, 1981), and (2) the PMF analysis has become a commonly used technology to predict a ``worst possible case`` flood scenario. For this PMF study, probable maximum precipitation (PMP) values were obtained for a local storm (thunderstorm) PMP event. These values were determined from the National Weather Services`s Hydrometeorological Report No. 49 (HMR 49).

  16. Efficacy of Intra-Arterial Infusion Chemotherapy for Head and Neck Cancers Using Coaxial Catheter Technique: Initial Experience

    SciTech Connect (OSTI)

    Tsurumaru, Daisuke Kuroiwa, Toshiro; Yabuuchi, Hidetake; Hirata, Hideki; Higaki, Yuichiro; Tomita, Kichinobu

    2007-04-15

    The aim of this study was to evaluate the efficacy of intra-arterial infusion chemotherapy for head and neck cancers using a coaxial catheter technique: the superficial temporal artery (STA)-coaxial catheter method. Thirty-one patients (21 males and 10 females; 37-83 years of age) with squamous cell carcinoma of the head and neck (maxilla, 2; epipharynx, 4; mesopharynx, 8; oral floor, 4; tongue, 10; lower gingiva, 1; buccal mucosa, 2) were treated by intra-arterial infusion chemotherapy. Four patients were excluded from the tumor-response evaluation because of a previous operation or impossibility of treatment due to catheter trouble. Forty-eight sessions of catheterization were performed. A guiding catheter was inserted into the STA and a microcatheter was advanced into the tumor-feeding artery via the guiding catheter under angiographic guidance. When the location of the tumor or its feeding artery was uncertain on angiography, computed tomographic angiography was performed. The anticancer agent carboplatin (CBDCA) was continuously injected for 24 h through the microcatheter from a portable infusion pump attached to the patient's waist. The total administration dose was 300-1300 mg per body. External radiotherapy was administered during intra-arterial chemotherapy at a total dose of 21-70.5 Gy.The initial response was complete response in 15 patients, partial response in 7 patients, and no change in 5 patients; the overall response rate was 81.5% (22/27). Complication-related catheter maintenance was observed in 15 of 48 sessions of catheterization. Injury and dislocation of the microcatheter occurred 10 times in 7 patients. Catheter infection was observed three times in each of two patients, and catheter occlusion and vasculitis occurred in two patients. Intra-arterial infusion chemotherapy via the STA-coaxial catheter method could have potential as a favorable treatment for head and neck tumors.

  17. What is the best method to fit time-resolved data? A comparison of the residual minimization and the maximum likelihood techniques as applied to experimental time-correlated, single-photon counting data

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Santra, Kalyan; Zhan, Jinchun; Song, Xueyu; Smith, Emily A.; Vaswani, Namrata; Petrich, Jacob W.

    2016-02-10

    The need for measuring fluorescence lifetimes of species in subdiffraction-limited volumes in, for example, stimulated emission depletion (STED) microscopy, entails the dual challenge of probing a small number of fluorophores and fitting the concomitant sparse data set to the appropriate excited-state decay function. This need has stimulated a further investigation into the relative merits of two fitting techniques commonly referred to as “residual minimization” (RM) and “maximum likelihood” (ML). Fluorescence decays of the well-characterized standard, rose bengal in methanol at room temperature (530 ± 10 ps), were acquired in a set of five experiments in which the total number ofmore » “photon counts” was approximately 20, 200, 1000, 3000, and 6000 and there were about 2–200 counts at the maxima of the respective decays. Each set of experiments was repeated 50 times to generate the appropriate statistics. Each of the 250 data sets was analyzed by ML and two different RM methods (differing in the weighting of residuals) using in-house routines and compared with a frequently used commercial RM routine. Convolution with a real instrument response function was always included in the fitting. While RM using Pearson’s weighting of residuals can recover the correct mean result with a total number of counts of 1000 or more, ML distinguishes itself by yielding, in all cases, the same mean lifetime within 2% of the accepted value. For 200 total counts and greater, ML always provides a standard deviation of <10% of the mean lifetime, and even at 20 total counts there is only 20% error in the mean lifetime. Here, the robustness of ML advocates its use for sparse data sets such as those acquired in some subdiffraction-limited microscopies, such as STED, and, more importantly, provides greater motivation for exploiting the time-resolved capacities of this technique to acquire and analyze fluorescence lifetime data.« less

  18. Chemoembolization of Hepatocellular Carcinoma with Hepasphere 30–60 μm. Safety and Efficacy Study

    SciTech Connect (OSTI)

    Malagari, Katerina; Pomoni, Maria; Moschouris, Hippokratis; Kelekis, Alexios; Charokopakis, Angelos Bouma, Evanthia Spyridopoulos, Themistoklis; Chatziioannou, Achilles; Sotirchos, Vlasios; Karampelas, Theodoros Tamvakopoulos, Constantin; Filippiadis, Dimitrios; Karagiannis, Enangelos; Marinis, Athanasios; Koskinas, John; Kelekis, Dimitrios A.

    2013-11-22

    Background: This study examined the safety, pharmacokinetics, and efficacy of transarterial chemoembolization of hepatocellular carcinoma (HCC) using a newly developed size of a superabsorbent polymer drug-eluting embolic material.MethodsForty-five patients with documented HCC (Child–Pugh score A/B: 55.5 %/44.5 %) were embolized with HepaSphere microspheres 30–60 μm with escalation of lesion, dose, and frequency of re-embolization. Local response was evaluated with modified response evaluation criteria in solid tumors (mRECIST). Plasma levels of doxorubicin were measured in 24 patients at baseline and at 5, 20, 40, 60, and 120 min, at 6, 24, and 48 h, and at 7 days, respectively, to determine doxorubicin in plasma (Cmax) and area under the curve (AUC). Measurements of three patients who underwent lipiodol-based conventional chemoembolization (c-TACE) were also performed.ResultsTACE with HepaSphere was well tolerated with an acceptable safety profile and no 30-day mortality. Response rates were calculated on intention-to-treat basis with complete response (CR) in 17.8 % reaching 22.2 % for the target lesion. Overall partial response (PR) was seen in 51.1 %, stable disease in 20 %, and progressive disease in 11.1 % of patients. Overall objective response (CR + PR), including patients treated at all dosages of doxorubicin, was seen in 68.9 % of cases. After a median follow-up of 15.6 months, 1-year survival is 100 %. Doxorubicin AUC was significantly lower in patients with HepaSphere 30–60 μm (35,195 ± 27,873 ng × min/ml) than in patients with conventional TACE (103,960 ± 16,652 ng × min/ml; p = 0.009). Cmax was also significantly lower with HepaSphere 30–60 μm (83.9 ± 32.1 ng/ml) compared with c-TACE (761.3 ± 58.8 ng/ml; p = 0.002).ConclusionHepaSphere 30–60 μm is an effective drug-eluting embolic material with a favourable pharmacokinetic profile.

  19. Comparative efficacy of 177Lu and 90Y for Anti-CD20 Pretargeted Radioimmunotherapy in Murine Lymphoma Xenograft Models

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Frost, Sofia H. L.; Frayo, Shani L.; Miller, Brian W.; Orozco, Johnnie J.; Booth, Garrett C.; Hylarides, Mark D.; Lin, Yukang; Green, Damian J.; Gopal, Ajay K.; Pagel, John M.; et al

    2015-03-18

    Purpose Pretargeted radioimmunotherapy (PRIT) is a multi-step method of selectively delivering high doses of radiotherapy to tumor cells while minimizing exposure to surrounding tissues. Yttrium-90 (90Y) and lutetium-177 (177Lu) are two of the most promising beta-particle emitting radionuclides used for radioimmunotherapy, which despite having similar chemistries differ distinctly in terms of radiophysical features. These differences may have important consequences for the absorbed dose to tumors and normal organs. Whereas 90Y has been successfully applied in a number of preclinical and clinical radioimmunotherapy settings, there have been few published pretargeting studies with 177Lu. We therefore compared the therapeutic potential of targetingmore » either 90Y or 177Lu to human B-cell lymphoma xenografts in mice. Methods Parallel experiments evaluating the biodistribution, imaging, dosimetry, therapeutic efficacy, and toxicity were performed in female athymic nude mice bearing either Ramos (Burkitt lymphoma) or Granta (mantle cell lymphoma) xenografts, utilizing an anti-CD20 antibodystreptavidin conjugate (1F5-SA) and an 90Y- or 177Lu-labeled 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA)-biotin second step reagent. Results The two radionuclides displayed comparable biodistributions in tumors and normal organs; however, the absorbed radiation dose delivered to tumor was more than twice as high for 90Y (1.3 Gy/MBq) as for 177Lu (0.6 Gy/MBq). More importantly, therapy with 90Y-DOTAbiotin was dramatically more effective than with 177Lu-DOTA-biotin, with 100% of Ramos xenograft-bearing mice cured with 37 MBq 90Y, whereas 0% were cured using identical amounts of 177Lu-DOTA-biotin. Similar results were observed in mice bearing Granta xenografts, with 80% of the mice cured with 90Y-PRIT and 0% cured with 177Lu-PRIT. Toxicities were comparable with both isotopes. Conclusion 90Y was therapeutically superior to 177Lu for streptavidin-biotin PRIT

  20. The effect of a Si-doped protective layer on the discharge characteristics of an alternating current plasma display panel

    SciTech Connect (OSTI)

    Lee, Don-Kyu; Park, Chung-Hoo; Lee, Hae June; Choi, Joon-Young; Kim, Dong-Hyun; Lee, Ho-Jun

    2007-10-15

    In order to improve the discharge characteristics such as discharge voltage, luminance, luminous efficacy, high-temperature misfiring, and lifetime, a small amount of Si was added to the MgO protective layer of a plasma display panel. The MgO protective layers were deposited by using an electron-beam evaporation method. The addition of Si onto a MgO protective layer can effectively increase the secondary electron emission coefficient so as to improve the discharge characteristics compared with using a pure MgO film. Both the surface characteristics of the protective layer and the electro-optical properties of 4 in. test panels were investigated, such as the discharge voltage, luminance, luminous efficacy, high-temperature misfiring, and lifetime. The results show that Si doping of 0.03%-0.04% in MgO has the best performance on plasma display panels.

  1. Percutaneous Transhepatic Biliary Metal Stent for Malignant Hilar Obstruction: Results and Predictive Factors for Efficacy in 159 Patients from a Single Center

    SciTech Connect (OSTI)

    Li, Mingwu Bai, Ming Qi, Xingshun Li, Kai Yin, Zhanxin; Wang, Jianhong; Wu, Wenbing Zhen, Luanluan He, Chuangye; Fan, Daiming; Zhang, Zhuoli; Han, Guohong E-mail: Hangh@fmmu.edu.cn

    2015-06-15

    AimTo investigate and compare the efficacy and safety of percutaneous transhepatic biliary stenting (PTBS) using a one- or two-stage procedure and determine the predictive factors for the efficacious treatment of malignant hilar obstruction (MHO).Methods159 consecutive patients with MHO who underwent PTBS were enrolled between January 2010 and June 2013. Patients were classified into one- or two-stage groups. Independent predictors of therapeutic success were evaluated using a logistic regression model.Results108 patients were treated with one-stage PTBS and 51 patients were treated with two-stage PTBS. The stents were technically successful in all patients. Successful drainage was achieved in 114 patients (71.4 %). A total of 42 early major complications were observed. Re-interventions were attempted in 23 patients during follow-up. The cumulative primary patency rates at 3, 6, and 12 months were 88, 71, and 48 %, respectively. Stent placement using a one- or two-stage procedure did not significantly affect therapeutic success, early major complications, median stent patency, or survival. A stent placed across the duodenal papilla was an independent predictor of therapeutic success (odds ratio = 0.262, 95 % confidence interval [0.107–0.642]). Patients with stents across papilla had a lower rate of cholangitis compared with patients who had a stent above papilla (7.1 vs. 20.3 %, respectively, p = 0.03).ConclusionsThe majority of patients with MHO who underwent one-stage PTBS showed similar efficacy and safety outcomes compared with those who underwent two-stage PTBS. Stent placement across the duodenal papilla was associated with a higher therapeutic success rate.

  2. Chief Joseph Kokanee Enhancement Project -- Strobe Light Deterrent Efficacy Test and Fish Behavior Determination at Grand Coulee Dam Third Powerplant Forebay

    SciTech Connect (OSTI)

    Simmons, Mary Ann; Johnson, Robert L.; McKinstry, Craig A.; Anglea, Steven M.; Simmons, Carver S.; Thorsten, Susan L.; Lecaire, R; Francis, S

    2002-01-29

    This report describes the work conducted during the first year of a long-term study to assess the efficacy of a prototype strobe light system in eliciting a negative phototactic response in kokanee and rainbow trout. The strobe light system is being evaluated as a means to prevent entrainment (and subsequent loss) of fish at the entrance to the forebay adjacent to the third powerplant at Grand Coulee Dam. Pacific Northwest National Laboratory and the Colville Confederated Tribes are collaborating on the three-year study being conducted for the Bonneville Power Administration and the Northwest Power Planning Council.

  3. Controls for Solid-State Lighting

    SciTech Connect (OSTI)

    Rubinstein, Francis

    2007-06-22

    This study predicts new hybrid lighting applications for LEDs. In hybrid lighting, LEDs provide a low-energy 'standby' light level while another, more powerful, efficient light source provides light for occupied periods. Lighting controls will allow the two light sources to work together through an appropriate control strategy, typically motion-sensing. There are no technical barriers preventing the use of low through high CRI LEDs for standby lighting in many interior and exterior applications today. The total luminous efficacy of LED systems could be raised by increasing the electrical efficiency of LED drivers to the maximum practically achievable level (94%). This would increase system luminous efficacy by 20-25%. The expected market volumes for many types of LEDs should justify the evolution of new LED drivers that use highly efficient ICs and reduce parts count by means of ASICs. Reducing their electronics parts count by offloading discrete components onto integrated circuits (IC) will allow manufacturers to reduce the cost of LED driver electronics. LED luminaire manufacturers will increasingly integrate the LED driver and thermal management directly in the LED fixture. LED luminaires of the future will likely have no need for separable lamp and ballast because the equipment life of all the LED luminaire components will all be about the same (50,000 hours). The controls and communications techniques used for communicating with conventional light sources, such as dimmable fluorescent lighting, are appropriate for LED illumination for energy management purposes. DALI has been used to control LED systems in new applications and the emerging ZigBee protocol could be used for LEDs as well. Major lighting companies are already moving in this direction. The most significant finding is that there is a significant opportunity to use LEDs today for standby lighting purposes. Conventional lighting systems can be made more efficient still by using LEDs to provide a low

  4. Chief Joseph Kokanee Enhancement Project; Strobe Light Deterrent Efficacy Test and Fish Behavior Determination at the Grand Coulee Dam Third Powerplant Forebay, 2004-2005 Annual Report.

    SciTech Connect (OSTI)

    Johnson, R.; McKinstry, C.; Cook, C.

    2005-02-01

    This report documents a four-year study(a) to assess the efficacy of a prototype strobe light system to elicit a negative phototactic response in kokanee (Oncorhynchus nerka kennerlyi) and rainbow trout (O. mykiss) at the entrance to the forebay of the third powerplant at Grand Coulee Dam. The work was conducted for the Bonneville Power Administration, U.S. Department of Energy, by Pacific Northwest National Laboratory (PNNL) in conjunction with the Confederated Tribes of the Colville Reservation (Colville Confederated Tribes). In this report, emphasis is placed on the methodology and results associated with the fourth project year and compared with findings from the previous years to provide an overall project summary. Since 1995, the Colville Confederated Tribes have managed the Chief Joseph Kokanee Enhancement Project as part of the Northwest Power and Conservation Council Fish and Wildlife Program. Project objectives have focused on understanding natural production of kokanee (a land-locked sockeye salmon) and other fish stocks in the area above Grand Coulee and Chief Joseph dams on the Columbia River (Figure S.1). A 42-month investigation from 1996 to 1999 determined that from 211,685 to 576,676 fish, including kokanee and rainbow trout, were entrained annually at Grand Coulee Dam. Analysis of the data found that 85% of the total entrainment occurred at the dam's third powerplant. Because these entrainment rates represent a significant loss to the tribal fisheries upstream of the dam, they have been judged unacceptable to fishery managers responsible for perpetuating the fishery in Lake Roosevelt. In an effort to reduce fish entrainment rates, the scope of work for the Chief Joseph Kokanee Enhancement Project was modified in 2001 to include a multiyear study of the efficacy of using strobe lights to deter fish from entering the third powerplant forebay. Pacific Northwest National Laboratory initiated the four-year study in collaboration with Colville Tribal

  5. 6-Thioguanine-loaded polymeric micelles deplete myeloid-derived suppressor cells and enhance the efficacy of T cell immunotherapy in tumor-bearing mice

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Jeanbart, Laura; Kourtis, Iraklis C.; van der Vlies, André J.; Swartz, Melody A.; Hubbell, Jeffrey A.

    2015-05-16

    Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature myeloid cells that suppress effector T cell responses and can reduce the efficacy of cancer immunotherapies. We previously showed that ultra-small polymer nanoparticles efficiently drain to the lymphatics after intradermal injection and target antigen-presenting cells, including Ly6chi Ly6g₋monocytic MDSCs (Mo-MDSCs), in skin-draining lymph nodes (LNs) and spleen. Here, we developed ultra-small polymer micelles loaded with 6-thioguanine (MC-TG), a cytotoxic drug used in the treatment of myelogenous leukemia, with the aim of killing Mo-MDSCs in tumor-bearing mice and thus enhancing T cell-mediated anti-tumor responses. We found that 2 days post-injection inmore » tumor-bearing mice (B16-F10 melanoma or E.G7-OVA thymoma), MC-TG depleted Mo-MDSCs in the spleen, Ly6clo Ly6g+ granulocytic MDSCs (G-MDSCs) in the draining LNs, and Gr1int Mo-MDSCs in the tumor. In both tumor models, MC-TG decreased the numbers of circulating Mo- and G-MDSCs, as well as of Ly6chi macrophages, for up to 7 days following a single administration. MDSC depletion was dose dependent and more effective with MC-TG than with equal doses of free TG. Finally, we tested whether this MDSC-depleting strategy might enhance cancer immunotherapies in the B16-F10 melanoma model. We found that MC-TG significantly improved the efficacy of adoptively transferred, OVA-specific CD8+ T cells in melanoma cells expressing OVA. Ultimately, these findings highlight the capacity of MC-TG in depleting MDSCs in the tumor microenvironment and show promise in promoting anti-tumor immunity when used in combination with T cell immunotherapies.« less

  6. Very Rapid High-amplitude Gamma-Ray Variability in Luminous Blazar...

    Office of Scientific and Technical Information (OSTI)

    US DOE Office of Science (DOE SC); National Aeronautics and Space Administration (NASA) United States 2013-03-20 English Journal Article Journal Name: The Astrophysical...

  7. HECTOSPEC AND HYDRA SPECTRA OF INFRARED LUMINOUS SOURCES IN THE AKARI NORTH ECLIPTIC POLE SURVEY FIELD

    SciTech Connect (OSTI)

    Shim, Hyunjin; Im, Myungshin; Jeon, Yiseul; Kim, Seong Jin; Lee, Hyung Mok; Ko, Jongwan; Karouzos, Marios; Papovich, Casey; Willmer, Christopher; Weiner, Benjamin J.

    2013-08-15

    We present spectra of 1796 sources selected in the AKARI North Ecliptic Pole Wide Survey field, obtained with MMT/Hectospec and WIYN/Hydra, for which we measure 1645 redshifts. We complemented the generic flux-limited spectroscopic surveys at 11 {mu}m and 15 {mu}m, with additional sources selected based on the MIR and optical colors. In MMT/Hectospec observations, the redshift identification rates are {approx}80% for objects with R < 21.5 mag. On the other hand, in WIYN/Hydra observations, the redshift identification rates are {approx}80% at R magnitudes brighter than 19 mag. The observed spectra were classified through the visual inspection or from the line diagnostics. We identified 1128 star-forming or absorption-line-dominated galaxies, 198 Type-1 active galactic nuclei (AGNs), 8 Type-2 AGNs, 121 Galactic stars, and 190 spectra in unknown category due to low signal-to-noise ratio. The spectra were flux-calibrated but to an accuracy of 0.1-0.18 dex for most of the targets and worse for the remainder. We derive star formation rates (SFRs) from the mid-infrared fluxes or from the optical emission lines, showing that our sample spans an SFR range of 0.1 to a few hundred M{sub Sun} yr{sup -1}. We find that the extinction inferred from the difference between the IR and optical SFR increases as the IR luminosity increases but with a large scatter.

  8. Prevalence of technical mesothorium in self-luminous compounds used by New Jersey radium dial workers

    SciTech Connect (OSTI)

    Keane, A.T.; Holtzmann, R.B.; Rundo, J.

    1994-05-01

    Forty-five sealed glass ampoules containing samples of radium dial paint prepared by the US Radium Corporation (USRC) and used by New Jersey dial workers in the period 1915--1928, were analyzed for radium-226 and radium-228 activity by high-resolution gamma-ray spectrometry. Radium-228 was found to be the dominant activating agent at the probable time of use in most of the sampled paints in which the ratio of radium-228 to radium-226 activity was determinable, the calculated radium-228 to radium-226 activity ratio in 1920 in these ranging from 7.2 to 10 (median 8.4), indicating that radium element chemically separated from commercialthorium ores (technical mesothorium) was used as the activator. Published isotopic activity ratios in USRC dial-paint samples that were appreciably in excess of those we found are shown invariably to be due to errors in calculation. Our results and information in the early literature suggested the hypothesis that dial paints used at USRC before July 1919 were activated with isotopically pure radium-226 whereas compounds used thereafter until the year 1925 were activated with technical mesothorium- Isotopic activity ratios predicted by the hypothesis compared well with median ratios observed in two groups of former workers. We conclude that inaccuracies in dates of hire and termination at USRC might well be the principal source of uncertainty in estimates of skeletal dose for former workers in whom the isotopic activity ratio has not been measured.

  9. DOE Publishes GATEWAY Report on High-Luminous-Flux LED Lighting in a

    Energy Savers [EERE]

    | Department of Energy Chromaticity Shift Modes of LED PAR38 Lamps DOE Publishes CALiPER Report on Chromaticity Shift Modes of LED PAR38 Lamps March 23, 2016 - 11:33am Addthis The U.S. Department of Energy's CALiPER program has released Report 20.5, which is part of a series of investigations on LED PAR38 lamps. The new report builds on CALiPER Report 20.4 by providing a tear-down analysis of its 32 LED PAR38 lamp models and also performing additional analyses on the spectroradiometric data

  10. DOE Publishes GATEWAY Report on High-Luminous-Flux LED Lighting...

    Broader source: Energy.gov (indexed) [DOE]

    and similar applications can benefit from the findings of this installation - including correctional facilities, military bases, and, more generally, street and area lighting. ...

  11. Very Rapid High-amplitude Gamma-Ray Variability in Luminous Blazar...

    Office of Scientific and Technical Information (OSTI)

    Org: US DOE Office of Science (DOE SC); National Aeronautics and Space Administration (NASA) Country of Publication: United States Language: English Subject: 79 ASTRONOMY AND...

  12. RECONCILING MODELS OF LUMINOUS BLAZARS WITH MAGNETIC FLUXES DETERMINED BY RADIO CORE-SHIFT MEASUREMENTS

    SciTech Connect (OSTI)

    Nalewajko, Krzysztof; Begelman, Mitchell C.; Sikora, Marek

    2014-11-20

    Estimates of magnetic field strength in relativistic jets of active galactic nuclei, obtained by measuring the frequency-dependent radio core location, imply that the total magnetic fluxes in those jets are consistent with the predictions of the magnetically arrested disk (MAD) scenario of jet formation. On the other hand, the magnetic field strength determines the luminosity of the synchrotron radiation, which forms the low-energy bump of the observed blazar spectral energy distribution (SED). The SEDs of the most powerful blazars are strongly dominated by the high-energy bump, which is most likely due to the external radiation Compton mechanism. This high Compton dominance may be difficult to reconcile with the MAD scenario, unless (1) the geometry of external radiation sources (broad-line region, hot-dust torus) is quasi-spherical rather than flat, or (2) most gamma-ray radiation is produced in jet regions of low magnetization, e.g., in magnetic reconnection layers or in fast jet spines.

  13. A comprehensive evaluation of the efficacy of leading oxime therapies in guinea pigs exposed to organophosphorus chemical warfare agents or pesticides

    SciTech Connect (OSTI)

    Wilhelm, Christina M.; Snider, Thomas H.; Babin, Michael C.; Jett, David A.

    2014-12-15

    The currently fielded pre-hospital therapeutic regimen for the treatment of organophosphorus (OP) poisoning in the United States (U.S.) is the administration of atropine in combination with an oxime antidote (2-PAM Cl) to reactivate inhibited acetylcholinesterase (AChE). Depending on clinical symptoms, an anticonvulsant, e.g., diazepam, may also be administered. Unfortunately, 2-PAM Cl does not offer sufficient protection across the range of OP threat agents, and there is some question as to whether it is the most effective oxime compound available. The objective of the present study is to identify an oxime antidote, under standardized and comparable conditions, that offers protection at the FDA approved human equivalent dose (HED) of 2-PAM Cl against tabun (GA), sarin (GB), soman (GD), cyclosarin (GF), and VX, and the pesticides paraoxon, chlorpyrifos oxon, and phorate oxon. Male Hartley guinea pigs were subcutaneously challenged with a lethal level of OP and treated at approximately 1 min post challenge with atropine followed by equimolar oxime therapy (2-PAM Cl, HI-6 DMS, obidoxime Cl{sub 2}, TMB-4, MMB4-DMS, HLö-7 DMS, MINA, and RS194B) or therapeutic-index (TI) level therapy (HI-6 DMS, MMB4-DMS, MINA, and RS194B). Clinical signs of toxicity were observed for 24 h post challenge and blood cholinesterase [AChE and butyrylcholinesterase (BChE)] activity was analyzed utilizing a modified Ellman's method. When the oxime is standardized against the HED of 2-PAM Cl for guinea pigs, the evidence from clinical observations, lethality, quality of life (QOL) scores, and cholinesterase reactivation rates across all OPs indicated that MMB4 DMS and HLö-7 DMS were the two most consistently efficacious oximes. - Highlights: • First comprehensive evaluation of leading AChE oxime reactivators • All oximes are compared against current U.S. therapy 2-PAM Cl. • Relative therapeutic oxime efficacies against OP CWNA and pesticides • Contribution to more effective antidotes

  14. Maximum voltage gradient, uniformity and brightness of dispenser cathodes

    SciTech Connect (OSTI)

    Turner, W.C.; Chen, Y.J.; Green, M.C.; Miram, G.V.; Nordquist, A.L.

    1988-01-01

    Initial measurements of current uniformity and intrinsic cathode brightness are presented a 5.1 cm diameter osmium alloy coated dispenser cathode. The data are obtained with a planar diode driven with a 35ns Blumlein pulse line. Pepper pot images are observed with a fast phosphor and gated camera. The current density and beamlet divergence angle are uniform within +-10% and a brightness J = 1.6E10A/m/sup 2/rad/sup 2/ is observed at a current density j=44A/cm/sup 2/. 6 refs., 2 figs., 2 tabs.

  15. OPEC's maximum oil revenue will be $80 billion per year

    SciTech Connect (OSTI)

    Steffes, D.W.

    1986-01-01

    OPEC's income from oil is less than $80 billion this year, only one fourth its 1981 revenue. The optimum revenue OPEC can expect is 15 MBB/D at $15/barrel. Energy conservation will continue despite falling prices because consumers no longer feel secure that OPEC can deliver needed supplies. Eleven concepts which affect the future world economic outlook include dependence upon petroleum and petroleum products, the condition of capital markets, low energy and commodity prices, the growth in money supply without a corresponding growth in investment, and the high debt level of the US and the developing countries.

  16. Method for Photovoltaic Maximum Power Point Estimation - Energy Innovation

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Mesdi Systems National Clean Energy Business Plan Competition Mesdi Systems University of Central Florida Liquid spray, generated by pressurized gas or high-frequency vibrations, typically results in up to 50 percent material waste, inconsistent droplet size, and physical limitations on minimum droplet size. To overcome these limitations, Mesdi's equipment uses electricity to generate droplets that are an order of magnitude smaller and very uniform in size with zero waste by harnessing a

  17. Engineer End Uses for Maximum Efficiency; Industrial Technologies...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    0 * August 2004 Industrial Technologies Program Suggested Actions * Review compressed air end uses and determine the required level of air pressure. * Review the compressed air end ...

  18. On Parallel Push-Relabel based Algorithms for Bipartite Maximum...

    Office of Scientific and Technical Information (OSTI)

    obtain a copy of this journal article from the publisher. Find in Google Scholar Find in Google Scholar Search WorldCat Search WorldCat to find libraries that may hold this journal

  19. Designs for maximum utilization of district heating systems ...

    Office of Scientific and Technical Information (OSTI)

    AND UTILIZATION; DISTRICT HEATING; DESIGN; ECONOMIC ANALYSIS; GEOTHERMAL DISTRICT HEATING; COST; EFFICIENCY; SENSITIVITY; ECONOMICS; GEOTHERMAL HEATING; HEATING Geothermal ...

  20. Total Estimated Contract Cost: Contract Option Period: Maximum...

    Office of Environmental Management (EM)

    LLC Contract Number: DE-AC30-11CC40015 Contract Type: Cost Plus Award Fee EM Contractor Fee December 2015 Site: Portsmouth Paducah Project Office Contract Name: Operation of DUF6

  1. Development of Basic Housing Systems for Maximum Affordability

    SciTech Connect (OSTI)

    Aglan, H.; Gibbons, A.; McQueen, T.M.; Morris, C.; Raines, J.; Wendt, R.L.

    1999-04-19

    The ability to provide safe, habitable, comfortable housing for very low income residents within the target budget of $10,000 presents unique design and construction challenges. However, a number of preliminary conclusions have been inferred as being important concepts relative to the study of affordable housing. The term affordable housing can have many meanings and research is needed to define this explicitly. As it is most often used, affordable housing refers to an economic relationship between the price of housing, household income and current interest rates available from a lending institution. There is no direct relationship between architectural style, construction technology or user needs and the concept of affordability. For any home to be affordable, the home owner must balance the combination of housing needs and desires within the limits of an actual budget. There are many misconceptions that affordable housing must be defined as housing for those who cannot afford the free-market price. The concept of affordable housing must also include a component that recognizes the quality of the housing as an important element of the design and construction. In addition, responses to local climate impacts are necessary and are always part of a regional expression of architectural design. By using careful planning and design it may be possible to construct a limited dwelling unit today for a sum of approximately $10,000. Since the organization of the construction process must involve the owner/occupants as well as other volunteers, the project must not only be well conceived, but well developed and coordinated.

  2. Maximum U.S. Active Seismic Crew Counts

    Gasoline and Diesel Fuel Update (EIA)

    Less electricity use this summer slightly offset by higher power costs The average U.S. household will use less electricity this summer than last summer because of expected cooler temperatures, but slightly higher electricity prices means summer power bills won't go down much. However, the outlook does vary across regions. Households in the South Atlantic states which includes Florida, Georgia, North Carolina, and Virginia will see the biggest savings. The average power bill in that region is

  3. Solar Tracing Sensors for Maximum Solar Concentrator Efficiency...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Technology Marketing SummaryConcentrating Solar Power (CSP) relies on thermodynamic processes to convert concentrated light into useful forms of energy. Accurate sun tracking ...

  4. Maximum Entry and Mandatory Separation Ages for Certain Security Employees

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2001-10-11

    The Policy in response to government-wide Office of Personnel Management regulations regarding establishment of mandatory retirement ages for employees in certain security related positions. Superseded by DOE P 310.1 Admin Chg 1, 12-1-11.

  5. Maximum U.S. Active Seismic Crew Counts

    Gasoline and Diesel Fuel Update (EIA)

    Marine Fuel Choice for Ocean- Going Vessels within Emissions Control Areas June 2015 Independent Statistics & Analysis www.eia.gov U.S. Department of Energy Washington, DC 20585 U.S. Energy Information Administration | Marine fuel choice for ocean going vessels within emissions control areas i This report was prepared by the U.S. Energy Information Administration (EIA), the statistical and analytical agency within the U.S. Department of Energy. By law, EIA's data, analyses, and forecasts are

  6. Conductivity maximum in a charged colloidal suspension (Journal...

    Office of Scientific and Technical Information (OSTI)

    We attribute this behavior to two main competing effects: colloid effective charge saturation due to counterion 'condensation' and diffusion slowdown due to the relaxation effect. ...

  7. Conductivity maximum in a charged colloidal suspension (Journal...

    Office of Scientific and Technical Information (OSTI)

    effects: colloid effective charge saturation due to counterion 'condensation' and diffusion slowdown due to the relaxation effect. In agreement with previous observations, we...

  8. The Maximum Value Method. (Conference) | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    Report Number(s): SAND2011-1176C 471256 DOE Contract Number: AC04-94AL85000 Resource Type: Conference Resource Relation: Conference: SIAM CS&E Conference held February 28, 2011 - ...

  9. Total Estimated Contract Cost: Contract Option Period: Maximum Fee

    Office of Environmental Management (EM)

    Definition and Scope Answer/Comment 1 What significant policy challenges are likely to remain unaddressed if we employ Title XIII's definition? The following points are not referencedd in EISA 1301. ・Power provider should also control the output fluctuation of renewable resources. ・The end user should have the choice of which form of power storage to be used. Certain types of energy conservation and storage could work better in different applications (e.g. not only electricity power but also

  10. A Requirement for Significant Reduction in the Maximum BTU Input...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    & Barbecue Association's Comments on DOE's Regulatory Burden RFI Department of Energy Request for Information: Reducing Regulatory Burden (Reply Comments) Re: Regulatory Burden RFI

  11. Maximum likelihood density modification by pattern recognition of structural motifs

    DOE Patents [OSTI]

    Terwilliger, Thomas C.

    2004-04-13

    An electron density for a crystallographic structure having protein regions and solvent regions is improved by maximizing the log likelihood of a set of structures factors {F.sub.h } using a local log-likelihood function: (x)+p(.rho.(x).vertline.SOLV)p.sub.SOLV (x)+p(.rho.(x).vertline.H)p.sub.H (x)], where p.sub.PROT (x) is the probability that x is in the protein region, p(.rho.(x).vertline.PROT) is the conditional probability for .rho.(x) given that x is in the protein region, and p.sub.SOLV (x) and p(.rho.(x).vertline.SOLV) are the corresponding quantities for the solvent region, p.sub.H (x) refers to the probability that there is a structural motif at a known location, with a known orientation, in the vicinity of the point x; and p(.rho.(x).vertline.H) is the probability distribution for electron density at this point given that the structural motif actually is present. One appropriate structural motif is a helical structure within the crystallographic structure.

  12. Total Estimated Contract Cost: Contract Option Period: Maximum...

    Office of Environmental Management (EM)

    & Wilcox Conversion Services, LLC Contract Number: DE-AC30-11CC40015 Contract Type: Cost Plus Award Fee EM Contractor Fee September 2015 Site: Portsmouth Paducah Project Office...

  13. A general maximum entropy framework for thermodynamic variational principles

    SciTech Connect (OSTI)

    Dewar, Roderick C.

    2014-12-05

    Minimum free energy principles are familiar in equilibrium thermodynamics, as expressions of the second law. They also appear in statistical mechanics as variational approximation schemes, such as the mean-field and steepest-descent approximations. These well-known minimum free energy principles are here unified and extended to any system analyzable by MaxEnt, including non-equilibrium systems. The MaxEnt Lagrangian associated with a generic MaxEnt distribution p defines a generalized potential Ψ for an arbitrary probability distribution p-hat, such that Ψ is a minimum at (p-hat) = p. Minimization of Ψ with respect to p-hat thus constitutes a generic variational principle, and is equivalent to minimizing the Kullback-Leibler divergence between p-hat and p. Illustrative examples of min–Ψ are given for equilibrium and non-equilibrium systems. An interpretation of changes in Ψ is given in terms of the second law, although min–Ψ itself is an intrinsic variational property of MaxEnt that is distinct from the second law.

  14. EERE Takes Important Steps to Ensure Maximum Impact of Technology...

    Broader source: Energy.gov (indexed) [DOE]

    the reduction in PV module production cost by an estimated 12 years, and created over ... Addthis Related Articles DOE-Sponsored Drilling Projects Demonstrate Significant CO2 ...

  15. ESTIMATING MAXIMUM SUSTAINABLE PRESSURE DURING CO2 INJECTION...

    Office of Scientific and Technical Information (OSTI)

    ... Presented at the Ground Water Protection Council 2008 Annual ... related to upwelling of deep CO2-rich fluids during the ... Engineers (SPE) Reservoir Evaluation & Engineering. ...

  16. Characterization and implementation of OSL dosimeters for use in evaluating the efficacy of organ-based tube current modulation for CT scans of the face and orbits

    SciTech Connect (OSTI)

    Marsh, R. M.; Silosky, M.

    2015-04-15

    Purpose: The purpose of this work was to characterize commercially available optically stimulated luminescent (OSL) dosimeters for general clinical applications and apply the results to the development of a method to evaluate the efficacy of a vendor-specific organ-based tube current modulation application for both phantom and clinical computed tomography (CT) scans of the face and orbits. Methods: This study consisted of three components: (1) thorough characterization of the dosimeters for CT scans in phantom, including evaluations of depletion, fading, angular dependence, and conversion from counts to absorbed dose; (2) evaluation of the efficacy of using plastic glasses to position the dosimeters over the eyes in both phantom and clinical studies; and (3) preliminary dosimetry measurements made using organ-based tube current modulation in computed tomography dose index (CTDI) and anthropomorphic phantom studies. Results: (1) Depletion effects were found to have a linear relationship with the output of the OSL dosimeters (R{sup 2} = 0.96). Fading was found to affect dosimeter readings during the first two hours following exposure but had no effect during the remaining 60-h period observed. No significant angular dependence was observed for the exposure conditions used in this study (with p-values ranging from 0.9 to 0.26 for all t-tests). Dosimeter counts varied linearly with absorbed dose when measured in the center and 12 o’clock positions of the CTDI phantoms. These linear models of counts versus absorbed dose had overlapping 95% confidence intervals for the intercepts but not for the slopes. (2) When dosimeters were positioned using safety glasses, there was no adverse effect on image quality, and there was no statistically significant difference between this placement and placement of the dosimeters directly on the eyes of the phantom (p = 0.24). (3) When using organ-based tube current modulation, the dose to the lens of the eye was reduced between 19% and

  17. Preliminary Study of the Efficacy of Using Nuclear Resonance Fluorescence with Quasi-Monoenergetic Gamma-Ray Sources for Nuclear Safeguards Assay

    SciTech Connect (OSTI)

    Johnson, M S; McNabb, D P; Hall, J M; Gonzalez, J J

    2011-02-17

    We have studied the efficacy of using nuclear resonance fluorescence (NRF)-based techniques to assay spent nuclear fuel for Pu content using quasi-monoenergetic sources. We have developed two techniques to precisely determine the Pu content in a fuel rod/pin. One of our approaches is virtually free of systematic uncertainties. Using analytical models, we have determined the amount of time required to measure the Pu content in spent nuclear fuel rods and spent fuel assemblies to within 1% precision. We note that Pu content can be determined in a fuel assembly about as fast as in a single fuel pin. The performance of NRF-based assay techniques with improved photon sources, which are currently under development, will also estimated. For follow-on research we propose to: (1) Construct research prototype detection systems for both of the NRF-based assay systems proposed in this paper and measure their calibration curves; (2) Determine the systematic errors associated with both assay methods, explore ways to reduce the errors and fold the results into future performance calculations; (3) Develop an algorithm to assay a fuel assembly; (4) Perform validation measurements using a single pin and scaled assemblies; (5) Research and develop current-mode detection and/or threshold detection techniques to improve assay times; (6) Characterize the flux of newly constructed sources and fold the results into the calculations presented here to determine the feasibility of a variety of proposed sources; and (7) Collaborate with others in the safeguards community to build a prototype system and perform an NRF-based assay demonstration on spent fuel.

  18. Highly Efficient Small Form Factor LED Retrofit Lamp

    SciTech Connect (OSTI)

    Steven Allen; Fred Palmer; Ming Li

    2011-09-11

    This report summarizes work to develop a high efficiency LED-based MR16 lamp downlight at OSRAM SYLVANIA under US Department of Energy contract DE-EE0000611. A new multichip LED package, electronic driver, and reflector optic were developed for these lamps. At steady-state, the lamp luminous flux was 409 lumens (lm), luminous efficacy of 87 lumens per watt (LPW), CRI (Ra) of 87, and R9 of 85 at a correlated color temperature (CCT) of 3285K. The LED alone achieved 120 lumens per watt efficacy and 600 lumen flux output at 25 C. The driver had 90% electrical conversion efficiency while maintaining excellent power quality with power factor >0.90 at a power of only 5 watts. Compared to similar existing MR16 lamps using LED sources, these lamps had much higher efficacy and color quality. The objective of this work was to demonstrate a LED-based MR16 retrofit lamp for replacement of 35W halogen MR16 lamps having (1) luminous flux of 500 lumens, (2) luminous efficacy of 100 lumens per watt, (3) beam angle less than 40{sup o} and center beam candlepower of at least 1000 candelas, and (4) excellent color quality.

  19. Comparative efficacy of 177Lu and 90Y for Anti-CD20 Pretargeted Radioimmunotherapy in Murine Lymphoma Xenograft Models

    SciTech Connect (OSTI)

    Frost, Sofia H. L.; Frayo, Shani L.; Miller, Brian W.; Orozco, Johnnie J.; Booth, Garrett C.; Hylarides, Mark D.; Lin, Yukang; Green, Damian J.; Gopal, Ajay K.; Pagel, John M.; Bck, Tom A.; Fisher, Darrell R.; Press, Oliver W.; Afrin, Farhat

    2015-03-18

    Purpose Pretargeted radioimmunotherapy (PRIT) is a multi-step method of selectively delivering high doses of radiotherapy to tumor cells while minimizing exposure to surrounding tissues. Yttrium-90 (90Y) and lutetium-177 (177Lu) are two of the most promising beta-particle emitting radionuclides used for radioimmunotherapy, which despite having similar chemistries differ distinctly in terms of radiophysical features. These differences may have important consequences for the absorbed dose to tumors and normal organs. Whereas 90Y has been successfully applied in a number of preclinical and clinical radioimmunotherapy settings, there have been few published pretargeting studies with 177Lu. We therefore compared the therapeutic potential of targeting either 90Y or 177Lu to human B-cell lymphoma xenografts in mice. Methods Parallel experiments evaluating the biodistribution, imaging, dosimetry, therapeutic efficacy, and toxicity were performed in female athymic nude mice bearing either Ramos (Burkitt lymphoma) or Granta (mantle cell lymphoma) xenografts, utilizing an anti-CD20 antibodystreptavidin conjugate (1F5-SA) and an 90Y- or 177Lu-labeled 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA)-biotin second step reagent. Results The two radionuclides displayed comparable biodistributions in tumors and normal organs; however, the absorbed radiation dose delivered to tumor was more than twice as high for 90Y (1.3 Gy/MBq) as for 177Lu (0.6 Gy/MBq). More importantly, therapy with 90Y-DOTAbiotin was dramatically more effective than with 177Lu-DOTA-biotin, with 100% of Ramos xenograft-bearing mice cured with 37 MBq 90Y, whereas 0% were cured using identical amounts of 177Lu-DOTA-biotin. Similar results were observed in mice bearing Granta xenografts, with 80% of the mice cured with 90Y-PRIT and 0

  20. Chief Joseph Kokanee Enhancement Project; Strobe Light Deterrent Efficacy Test and Fish Behavior Determination at the Grand Coulee Dam Third Powerplant Forebay, 2002-2003 Annual Report.

    SciTech Connect (OSTI)

    Johnson, R.; McKinstry, C.; Simmons, C.

    2003-01-01

    Since 1995, the Confederated Tribes of the Colville Reservation (Colville Confederated Tribes) have managed the Chief Joseph Kokanee Enhancement Project as part of the Northwest Power Planning Council (NWPPC) Fish and Wildlife Program. Project objectives have focused on understanding natural production of kokanee (a land-locked sockeye salmon) and other fish stocks in the area above Grand Coulee and Chief Joseph Dams on the Columbia River. A 42-month investigation concluded that entrainment at Grand Coulee Dam ranged from 211,685 to 576,676 fish annually. Further analysis revealed that 85% of the total entrainment occurred at the dam's third powerplant. These numbers represent a significant loss to the tribal fisheries upstream of the dam. In response to a suggestion by the NWPPC Independent Scientific Review Panel, the scope of work for the Chief Joseph Kokanee Enhancement Project was expanded to include a multiyear pilot test of a strobe light system to help mitigate fish entrainment. This report details the work conducted during the second year of the study by researchers of the Colville Confederated Tribes in collaboration with the Pacific Northwest National Laboratory. The 2002 study period extended from May 18 through July 30. The objective of the study was to determine the efficacy of a prototype strobe light system to elicit a negative phototactic response in kokanee and rainbow trout. The prototype system consisted of six strobe lights affixed to an aluminum frame suspended vertically underwater from a barge secured in the center of the entrance to the third powerplant forebay. The lights, controlled by a computer, were aimed to illuminate a specific region directly upstream of the barge. Three light level treatments were used: 6 of 6 lights on, 3 of 6 lights on, and all lights off. These three treatment conditions were applied for an entire 24-hr day and were randomly assigned within a 3-day block throughout the study period. A seven-transducer splitbeam

  1. Long-Term Efficacy and Toxicity of Low-Dose-Rate {sup 125}I Prostate Brachytherapy as Monotherapy in Low-, Intermediate-, and High-Risk Prostate Cancer

    SciTech Connect (OSTI)

    Kittel, Jeffrey A.; Reddy, Chandana A.; Smith, Kristin L.; Stephans, Kevin L.; Tendulkar, Rahul D.; Ulchaker, James; Angermeier, Kenneth; Campbell, Steven; Stephenson, Andrew; Klein, Eric A.; Wilkinson, D. Allan; Ciezki, Jay P.

    2015-07-15

    Purpose/Objectives: To report long-term efficacy and toxicity for a single-institution cohort of patients treated with low-dose-rate prostate brachytherapy permanent implant (PI) monotherapy. Methods and Materials: From 1996 to 2007, 1989 patients with low-risk (61.3%), intermediate-risk (29.8%), high-intermediate-risk (4.5%), and high-risk prostate cancer (4.4%) were treated with PI and followed up prospectively in a registry. All patients were treated with {sup 125}I monotherapy to 144 Gy. Late toxicity was coded retrospectively according to a modified Common Terminology Criteria for Adverse Events 4.0 scale. The rates of biochemical relapse-free survival (bRFS), distant metastasis-free survival (DMFS), overall survival (OS), and prostate cancer–specific mortality (PCSM) were calculated. We identified factors associated with late grade ≥3 genitourinary (GU) and gastrointestinal (GI) toxicity, bRFS, DMFS, OS, PCSM, and incontinence. Results: The median age of the patients was 67 years, and the median overall and prostate-specific antigen follow-up times were 6.8 years and 5.8 years, respectively. The overall 5-year rates for bRFS, DMFS, OS, and PCSM were 91.9%, 97.8%, 93.7%, and 0.71%, respectively. The 10-year rates were 81.5%, 91.5%, 76.1%, and 2.5%, respectively. The overall rates of late grade ≥3 GU and GI toxicity were 7.6% and 0.8%, respectively. On multivariable analysis, age and prostate length were significantly associated with increased risk of late grade ≥3 GU toxicity. The risk of incontinence was highly correlated with both pre-PI and post-PI transurethral resection of the prostate. Conclusions: Prostate brachytherapy as monotherapy is an effective treatment for low-risk and low-intermediate-risk prostate cancer and appears promising as a treatment for high-intermediate-risk and high-risk prostate cancer. Significant long-term toxicities are rare when brachytherapy is performed as monotherapy.

  2. Therapeutic efficacy of boron neutron capture therapy mediated by boron-rich liposomes for oral cancer in the hamster cheek pouch model

    SciTech Connect (OSTI)

    Heber, Elisa M.; Hawthorne, M. Frederick; Kueffer, Peter J.; Garabalino, Marcela A.; Thorp, Silvia I.; Pozzi, Emiliano C. C.; Hughes, Andrea Monti; Maitz, Charles A.; Jalisatgi, Satish S.; Nigg, David W.; Curotto, Paula; Trivillin, Vernica A.; Schwint, Amanda E.

    2014-11-11

    Unilamellar liposomes formulated with an equimolar mixture of cholesterol and 1,2-distearoyl-sn-glycero-3-phosphocholine, incorporating K[nido-7-CH3(CH2)15-7,8-C2B9H11] in the lipid bilayer, and encapsulating Na3[1-(2-B10-H9)-2-NH3B10H8] were prepared by probe sonication and investigated in vivo. Microwave assisted digestion followed by inductively coupled plasma-optical emission spectroscopy was utilized to determine the biodistribution of boron in various tissues following either a single tail vein injection or two identical injections (separated by 24 hours) of the liposomal suspension in BALB/c mice bearing EMT6 mammary adenocarcinomas in their right flank. Double-injection protocols resulted in a boron content in the tumor exceeding 50 g of boron per gram of tissue for 48 to 72 hours subsequent to the initial injection while tumor:blood boron ratios were more ideal from 54 hours (1.9:1) to 96 hours (5.7:1) subsequent to the initial injection. Tumor bearing mice were given a double-injection of liposomes containing the 10B-enriched analogs of the aforementioned agents and subjected to a 30 minute irradiation by thermal neutrons with a flux of 8.8 x 108 (7%) neutrons/cm2 s integrated over the energy range of 0.0 0.414 eV. Significant tumor response for a single BNCT treatment was demonstrated by growth curves versus a control group. Vastly diminished tumor growth was witnessed at 14 days (186% increase versus 1551% in controls) in mice that were given a second injection/radiation treatment 7 days after the first. Mice given a one hour neutron irradiation following the double-injection of liposomes had a similar response (169% increase at 14 days) suggesting that neutron fluence is the limiting factor towards BNCT efficacy in this study.

  3. "Research to Improve the Efficacy of Captive Broodstock Programs and Advance Hatchery Reform Throughout the Columbia River Basin." [from the Abstract], 2008-2009 Progress Report.

    SciTech Connect (OSTI)

    Berejikian, Barry A.

    2009-08-18

    This project was developed to conduct research to improve the efficacy of captive broodstock programs and advance hatchery reform throughout the Columbia River Basin. The project has three objectives: (1) maintain adaptive life history characteristics in Chinook salmon, (2) improve imprinting in juvenile sockeye salmon, and (3) match wild phenotypes in Chinook and sockeye salmon reared in hatcheries. A summary of the results are as follows: Objective 1: The ratio of jack to adult male Chinook salmon were varied in experimental breeding populations to test the hypothesis that reproductive success of the two male phenotypes would vary with their relative frequency in the population. Adult Chinook salmon males nearly always obtained primary access to nesting females and were first to enter the nest at the time of spawning. Jack male spawning occurred primarily by establishing satellite positions downstream of the courting pair, and 'sneaking' into the nest at the time of spawning. Male dominance hierarchies were fairly stable and strongly correlated with the order of nest entry at the time of spawning. Observed participation in spawning events and adult-to-fry reproductive success of jack and adult males was consistent with a negative frequency-dependent selection model. Overall, jack males sired an average of 21% of the offspring produced across a range of jack male frequencies. Implications of these and additional findings on Chinook salmon hatchery broodstock management will be presented in the FY 2009 Annual Report. Objective 2: To determine the critical period(s) for imprinting for sockeye salmon, juvenile salmon were exposed to known odorants at key developmental stages. Molecular assessments of imprinting-induced changes in odorant receptor gene expression indicated that regulation of odorant expression is influenced by developmental status and odor exposure history. Expression levels of basic amino acid receptor (BAAR) mRNA in the olfactory epithelium

  4. "Research to Improve the Efficacy of Captive Broodstock Programs and Advance Hatchery Reform Throughout the Columbia River Basin." [from the Abstract], 2007-2008 Annual Progress Report.

    SciTech Connect (OSTI)

    Berejikian, Barry A.

    2009-04-08

    This project was developed to conduct research to improve the efficacy of captive broodstock programs and advance hatchery reform throughout the Columbia river basin. The project has three objectives: (1) maintain adaptive life history characteristics in Chinook salmon, (2) improve imprinting in juvenile sockeye salmon, and (3) match wild phenotypes in Chinook and sockeye salmon reared in hatcheries. A summary of the results are as follows: Objective 1: Adult and jack Chinook salmon males were stocked into four replicate spawning channels at a constant density (N = 16 per breeding group), but different ratios, and were left to spawn naturally with a fixed number of females (N = 6 per breeding group). Adult males obtained primary access to females and were first to enter the nest at the time of spawning. Jack male spawning occurred primarily by establishing satellite positions downstream of the courting pair, and 'sneaking' into the nest at the time of spawning. Male dominance hierarchies were fairly stable and strongly correlated with the order of nest entry at the time of spawning. Spawning participation by jack and adult males is consistent with a negative frequency dependent selection model, which means that selection during spawning favors the rarer life history form. Results of DNA parentage assignments will be analyzed to estimate adult-to-fry fitness of each male. Objective 2: To determine the critical period(s) for imprinting for sockeye salmon, juvenile salmon were exposed to known odorants at key developmental stages. Molecular assessments of imprinting-induced changes in odorant receptor gene expression indicated that regulation of odorant expression is influenced by developmental status and odor exposure history. The results suggest that sockeye salmon are capable of imprinting to homing cues during the developmental periods that correspond to several of current release strategies employed as part of the Captive Broodstock program (specifically

  5. Chief Joseph Kokanee Enhancement Project : Strobe Light Deterrent Efficacy Test and Fish Behavior Determination at Grond Coulee Dam Third Powerplant Forebay.

    SciTech Connect (OSTI)

    Simmons, M.A.; McKinstry, C.A.; Simmons, C.S.

    2002-01-01

    Since 1995, the Colville Confederated Tribes have managed the Chief Joseph Kokanee Enhancement Project as part of the Northwest Power Planning Council's (NWPPC) Fish and Wildlife Program. Project objectives have focused on understanding natural production of kokanee (a land-locked sockeye salmon) and other fish stocks in the area above Grand Coulee and Chief Joseph Dams on the Columbia River. A 42-month investigation concluded that entrainment at Grand Coulee Dam ranged from 211,685 to 576,676 fish annually. Further analysis revealed that 85% of the total entrainment occurred at the dam's third powerplant. These numbers represent a significant loss to the tribal fisheries upstream of the dam. In response to a suggestion by the NWPPC's Independent Scientific Review Panel, the scope of work for the Chief Joseph Kokanee Enhancement Project was expanded to include a multiyear pilot test of a strobe light system to help mitigate fish entrainment. This report details the work conducted during the first year of the study by researchers of the Colville Confederated Tribes in collaboration with the Pacific Northwest National Laboratory (PNNL). The objective of the study was to determine the efficacy of a prototype strobe light system to elicit a negative phototactic response in kokanee and rainbow trout. Analysis of the effect of strobe lights on the distribution (numbers) and behavior of kokanee and rainbow trout was based on 51, 683 fish targets detected during the study period (June 30 through August 1, 2001). Study findings include the following: (1) Analysis of the count data indicated that significantly more fish were present when the lights were on compared to off. This was true for both the 24-hr tests as well as the 1-hr tests. Powerplant discharge, distance from lights, and date were significant factors in the analysis. (2) Behavioral results indicated that fish within 14 m of the lights were trying to avoid the lights by swimming across the lighted region or

  6. Chief Joseph Kokanee Enhancement Project; Strobe Light Deterrent Efficacy Test and Fish Behavior Determination at the Grand Coulee Dam Third Powerplant Forebay, 2003-2004 Annual Report.

    SciTech Connect (OSTI)

    Simmons, M.; McKinstry, C.; Cook, C.

    2004-01-01

    Since 1995, the Confederated Tribes of the Colville Reservation (Colville Confederated Tribes) have managed the Chief Joseph Kokanee Enhancement Project as part of the Northwest Power Planning Council (NWPPC) Fish and Wildlife Program. Project objectives have focused on understanding natural production of kokanee (a land-locked sockeye salmon) and other fish stocks in the area above Grand Coulee and Chief Joseph Dams on the Columbia River. A 42-month investigation from 1996 to 1999 determined that from 211,685 to 576,676 fish were entrained annually at Grand Coulee Dam. Analysis of the entrainment data found that 85% of the total entrainment occurred at the dam's third powerplant. These numbers represent a significant loss to the tribal fisheries upstream of the dam. In response to a suggestion by the NWPPC Independent Scientific Review Panel, the scope of work for the Chief Joseph Kokanee Enhancement Project was expanded to include a multiyear pilot test of a strobe light system to help mitigate fish entrainment. This report details the work conducted during the third year of the strobe light study by researchers of the Colville Confederated Tribes in collaboration with the Pacific Northwest National Laboratory. The objective of the study is to determine the efficacy of a prototype strobe light system to elicit a negative phototactic response in kokanee and rainbow trout under field conditions. The prototype system consists of six strobe lights affixed to an aluminum frame suspended 15 m vertically underwater from a barge secured in the center of the entrance to the third powerplant forebay. The lights, controlled by a computer, illuminate a region directly upstream of the barge. The 2003 study period extended from June 16 through August 1. Three light treatments were used: all six lights on for 24 hours, all lights off for 24 hours, and three of six lights cycled on and off every hour for 24 hours. These three treatment conditions were assigned randomly within a

  7. Vacuum ultra-violet emission of plasma discharges with high Xe partial pressure using a cathode protective layer with high secondary electron emission

    SciTech Connect (OSTI)

    Zhu, Di; Song, Le; Zhang, Xiong; Kajiyama, Hiroshi

    2014-02-14

    In this work, the mechanism of the vacuum ultra-violet (VUV) emission of plasma discharges, with high Xe partial pressure and high ion-induced secondary electrons emission protective layer, is studied by measuring the VUV light emission directly and comparing it with two-dimensional simulations. From the panel measurement, we find that the high intensity of excimer VUV mainly contributes to the high luminous efficacy of SrCaO-plasma display panels (PDP) at a low sustain voltage. The unchanged Xe excitation efficiency indicates that the electron temperature is not decreased by the high secondary electrons emission protective layer, even though the sustain voltage is much lower. From the two-dimensional simulations, we can find that the ratio of excimer VUV to resonant VUV, which is determined by the collision rate in the discharge, is only significantly affected by the Xe partial pressure, while it is independent of the sustain voltage and the secondary-electrons-emission capability of protective layer. The unchanged average electron energy at the moment when the electric field becomes maximum confirms that the improvement of the VUV production efficiency mainly is attributed to the increase in electron heating efficiency of a PDP with high ion-induced secondary electrons emission protective layer. Combining the experimental and the simulation results, we conclude about the mechanism by which the VUV production is improved for the plasma display panel with a high Xe partial pressure and a cold cathode with high ion-induced secondary electrons emission.

  8. High Quality Down Lighting Luminaire with 73% Overall System Efficiency

    SciTech Connect (OSTI)

    Robert Harrison; Steven C. Allen; Joseph Bernier; Robert Harrison

    2010-08-31

    This report summarizes work to develop a high flux, high efficiency LED-based downlight at OSRAM SYLVANIA under US Department of Energy contract DE-FC26-08NT01582. A new high power LED and electronic driver were developed for these downlights. The LED achieved 100 lumens per watt efficacy and 1700 lumen flux output at a correlated color temperature of 3500K. The driver had 90% electrical conversion efficiency while maintaining excellent power quality with power factor >0.99, and total harmonic distortion <10%. Two styles of downlights using the LED and driver were shown to exceed the project targets for steady-state luminous efficacy and flux of 70 lumens per watt and 1300 lumens, respectively. Compared to similar existing downlights using compact fluorescent or LED sources, these downlights had much higher efficacy at nearly the same luminous flux.

  9. Pretreatment [{sup 18}F]-fluoro-2-deoxy-glucose Positron Emission Tomography Maximum Standardized Uptake Value as Predictor of Distant Metastasis in Early-Stage Non-Small Cell Lung Cancer Treated With Definitive Radiation Therapy: Rethinking the Role of Positron Emission Tomography in Personalizing Treatment Based on Risk Status

    SciTech Connect (OSTI)

    Nair, Vimoj J.; MacRae, Robert; Sirisegaram, Abby; Pantarotto, Jason R.

    2014-02-01

    Purpose: The aim of this study was to determine whether the preradiation maximum standardized uptake value (SUV{sub max}) of the primary tumor for [{sup 18}F]-fluoro-2-deoxy-glucose positron emission tomography (FDG-PET) has a prognostic significance in patients with Stage T1 or T2N0 non-small cell lung cancer (NSCLC) treated with curative radiation therapy, whether conventional or stereotactic body radiation therapy (SBRT). Methods and Materials: Between January 2007 and December 2011, a total of 163 patients (180 tumors) with medically inoperable histologically proven Stage T1 or T2N0 NSCLC and treated with radiation therapy (both conventional and SBRT) were entered in a research ethics board approved database. All patients received pretreatment FDG-PET / computed tomography (CT) at 1 institution with consistent acquisition technique. The medical records and radiologic images of these patients were analyzed. Results: The overall survival at 2 years and 3 years for the whole group was 76% and 67%, respectively. The mean and median SUV{sub max} were 8.1 and 7, respectively. Progression-free survival at 2 years with SUV{sub max} <7 was better than that of the patients with tumor SUV{sub max} ?7 (67% vs 51%; P=.0096). Tumors with SUV{sub max} ?7 were associated with a worse regional recurrence-free survival and distant metastasis-free survival. In the multivariate analysis, SUV{sub max} ?7 was an independent prognostic factor for distant metastasis-free survival. Conclusion: In early-stage NSCLC managed with radiation alone, patients with SUV{sub max} ?7 on FDG-PET / CT scan have poorer outcomes and high risk of progression, possibly because of aggressive biology. There is a potential role for adjuvant therapies for these high-risk patients with intent to improve outcomes.

  10. Change of Maximum Standardized Uptake Value Slope in Dynamic Triphasic [{sup 18}F]-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Distinguishes Malignancy From Postradiation Inflammation in Head-and-Neck Squamous Cell Carcinoma: A Prospective Trial

    SciTech Connect (OSTI)

    Anderson, Carryn M.; Chang, Tangel; Graham, Michael M.; Marquardt, Michael D.; Button, Anna; Smith, Brian J.; Menda, Yusuf; Sun, Wenqing; Pagedar, Nitin A.; Buatti, John M.

    2015-03-01

    Purpose: To evaluate dynamic [{sup 18}F]-fluorodeoxyglucose (FDG) uptake methodology as a post–radiation therapy (RT) response assessment tool, potentially enabling accurate tumor and therapy-related inflammation differentiation, improving the posttherapy value of FDG–positron emission tomography/computed tomography (FDG-PET/CT). Methods and Materials: We prospectively enrolled head-and-neck squamous cell carcinoma patients who completed RT, with scheduled 3-month post-RT FDG-PET/CT. Patients underwent our standard whole-body PET/CT scan at 90 minutes, with the addition of head-and-neck PET/CT scans at 60 and 120 minutes. Maximum standardized uptake values (SUV{sub max}) of regions of interest were measured at 60, 90, and 120 minutes. The SUV{sub max} slope between 60 and 120 minutes and change of SUV{sub max} slope before and after 90 minutes were calculated. Data were analyzed by primary site and nodal site disease status using the Cox regression model and Wilcoxon rank sum test. Outcomes were based on pathologic and clinical follow-up. Results: A total of 84 patients were enrolled, with 79 primary and 43 nodal evaluable sites. Twenty-eight sites were interpreted as positive or equivocal (18 primary, 8 nodal, 2 distant) on 3-month 90-minute FDG-PET/CT. Median follow-up was 13.3 months. All measured SUV endpoints predicted recurrence. Change of SUV{sub max} slope after 90 minutes more accurately identified nonrecurrence in positive or equivocal sites than our current standard of SUV{sub max} ≥2.5 (P=.02). Conclusions: The positive predictive value of post-RT FDG-PET/CT may significantly improve using novel second derivative analysis of dynamic triphasic FDG-PET/CT SUV{sub max} slope, accurately distinguishing tumor from inflammation on positive and equivocal scans.

  11. Five-Year Analysis of Treatment Efficacy and Cosmesis by the American Society of Breast Surgeons MammoSite Breast Brachytherapy Registry Trial in Patients Treated With Accelerated Partial Breast Irradiation

    SciTech Connect (OSTI)

    Vicini, Frank; Beitsch, Peter; Quiet, Coral; Gittleman, Mark; Zannis, Vic; Fine, Ricky; Whitworth, Pat; Kuerer, Henry; Haffty, Bruce; Lyden, Maureen

    2011-03-01

    Purpose: To present 5-year data on treatment efficacy, cosmetic results, and toxicities for patients enrolled on the American Society of Breast Surgeons MammoSite breast brachytherapy registry trial. Methods and Materials: A total of 1440 patients (1449 cases) with early-stage breast cancer receiving breast-conserving therapy were treated with the MammoSite device to deliver accelerated partial-breast irradiation (APBI) (34 Gy in 3.4-Gy fractions). Of 1449 cases, 1255 (87%) had invasive breast cancer (IBC) (median size, 10 mm) and 194 (13%) had ductal carcinoma in situ (DCIS) (median size, 8 mm). Median follow-up was 54 months. Results: Thirty-seven cases (2.6%) developed an ipsilateral breast tumor recurrence (IBTR), for a 5-year actuarial rate of 3.80% (3.86% for IBC and 3.39% for DCIS). Negative estrogen receptor status (p = 0.0011) was the only clinical, pathologic, or treatment-related variable associated with IBTR for patients with IBC and young age (<50 years; p = 0.0096) and positive margin status (p = 0.0126) in those with DCIS. The percentage of breasts with good/excellent cosmetic results at 60 months (n = 371) was 90.6%. Symptomatic breast seromas were reported in 13.0% of cases, and 2.3% developed fat necrosis. A subset analysis of the first 400 consecutive cases enrolled was performed (352 with IBC, 48 DCIS). With a median follow-up of 60.5 months, the 5-year actuarial rate of IBTR was 3.04%. Conclusion: Treatment efficacy, cosmesis, and toxicity 5 years after treatment with APBI using the MammoSite device are good and similar to those reported with other forms of APBI with similar follow-up.

  12. DES J0454–4448: Discovery of the first luminous z ≥ 6 quasar from the Dark Energy Survey

    SciTech Connect (OSTI)

    Reed, S. L.

    2015-10-28

    We present the first results of a survey for high-redshift, z ≥ 6, quasars using izY multicolour photometric observations from the Dark Energy Survey (DES). Here we report the discovery and spectroscopic confirmation of the zAB, YAB = 20.2, 20.2 (M1450 = –26.5) quasar DES J0454–4448 with a redshift of z = 6.09±0.02 based on the onset of the Ly α forest and an H i near zone size of 4.1+1.1–1.2 proper Mpc. The quasar was selected as an i-band drop out with i–z = 2.46 and zAB < 21.5 from an area of ~300 deg2. It is the brightest of our 43 candidates and was identified for spectroscopic follow-up solely based on the DES i–z and z–Y colours. The quasar is detected by WISE and has W1AB = 19.68. The discovery of one spectroscopically confirmed quasar with 5.7 < z < 6.5 and zAB ≤ 20.2 is consistent with recent determinations of the luminosity function at z ~ 6. DES when completed will have imaged ~5000 deg2 to YAB = 23.0 (5σ point source) and we expect to discover 50–100 new quasars with z > 6 including 3–10 with z > 7 dramatically increasing the numbers of quasars currently known that are suitable for detailed studies.

  13. DES J0454–4448: Discovery of the first luminous z ≥ 6 quasar from the Dark Energy Survey

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Reed, S. L.

    2015-10-28

    We present the first results of a survey for high-redshift, z ≥ 6, quasars using izY multicolour photometric observations from the Dark Energy Survey (DES). Here we report the discovery and spectroscopic confirmation of the zAB, YAB = 20.2, 20.2 (M1450 = –26.5) quasar DES J0454–4448 with a redshift of z = 6.09±0.02 based on the onset of the Ly α forest and an H i near zone size of 4.1+1.1–1.2 proper Mpc. The quasar was selected as an i-band drop out with i–z = 2.46 and zAB < 21.5 from an area of ~300 deg2. It is the brightestmore » of our 43 candidates and was identified for spectroscopic follow-up solely based on the DES i–z and z–Y colours. The quasar is detected by WISE and has W1AB = 19.68. The discovery of one spectroscopically confirmed quasar with 5.7 < z < 6.5 and zAB ≤ 20.2 is consistent with recent determinations of the luminosity function at z ~ 6. DES when completed will have imaged ~5000 deg2 to YAB = 23.0 (5σ point source) and we expect to discover 50–100 new quasars with z > 6 including 3–10 with z > 7 dramatically increasing the numbers of quasars currently known that are suitable for detailed studies.« less

  14. Supermassive black holes with high accretion rates in active galactic nuclei. II. The most luminous standard candles in the universe

    SciTech Connect (OSTI)

    Wang, Jian-Min; Du, Pu; Hu, Chen; Qiu, Jie; Li, Yan-Rong [Key Laboratory for Particle Astrophysics, Institute of High Energy Physics, Chinese Academy of Sciences, 19B Yuquan Road, Beijing 100049 (China); Netzer, Hagai; Kaspi, Shai [Wise Observatory, School of Physics and Astronomy, Tel-Aviv University, Tel-Aviv 69978 (Israel); Bai, Jin-Ming; Wang, Fang [Yunnan Observatory, Chinese Academy of Sciences, Kunming 650011, Yunnan (China); Lu, Kai-Xing [Astronomy Department, Beijing Normal University, Beijing 100875 (China); Collaboration: SEAMBH collaboration

    2014-10-01

    This is the second in a series of papers reporting on a large reverberation mapping (RM) campaign to measure black hole (BH) mass in high accretion rate active galactic nuclei (AGNs). The goal is to identify super-Eddington accreting massive black holes (SEAMBHs) and to use their unique properties to construct a new method for measuring cosmological distances. Based on theoretical models, the saturated bolometric luminosity of such sources is proportional to the BH mass, which can be used to obtain their distance. Here we report on five new RM measurements and show that in four of the cases, we can measure the BH mass and three of these sources are SEAMBHs. Together with the three sources from our earlier work, we now have six new sources of this type. We use a novel method based on a minimal radiation efficiency to identify nine additional SEAMBHs from earlier RM-based mass measurements. We use a Bayesian analysis to determine the parameters of the new distance expression and the method uncertainties from the observed properties of the objects in the sample. The ratio of the newly measured distances to the standard cosmological ones has a mean scatter of 0.14 dex, indicating that SEAMBHs can be use as cosmological distance probes. With their high luminosity, long period of activity, and large numbers at high redshifts, SEAMBHs have a potential to extend the cosmic distance ladder beyond the range now explored by Type Ia supernovae.

  15. DES14X3taz: A type I superluminous supernova showing a luminous, rapidly cooling initial pre-peak bump

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Smith, M.

    2016-02-03

    Here, we present DES14X3taz, a new hydrogen-poor superluminous supernova (SLSN-I) discovered by the Dark Energy Survey (DES) supernova program, with additional photometric data provided by the Survey Using DECam for Superluminous Supernovae. Spectra obtained using Optical System for Imaging and low-Intermediate-Resolution Integrated Spectroscopy on the Gran Telescopio CANARIAS show DES14X3taz is an SLSN-I at z = 0.608. Multi-color photometry reveals a double-peaked light curve: a blue and relatively bright initial peak that fades rapidly prior to the slower rise of the main light curve. Our multi-color photometry allows us, for the first time, to show that the initial peak cools from 22,000more » to 8000 K over 15 rest-frame days, and is faster and brighter than any published core-collapse supernova, reaching 30% of the bolometric luminosity of the main peak. No physical (56)Ni-powered model can fit this initial peak. We show that a shock-cooling model followed by a magnetar driving the second phase of the light curve can adequately explain the entire light curve of DES14X3taz. Models involving the shock-cooling of extended circumstellar material at a distance of ≃400 R⊙ are preferred over the cooling of shock-heated surface layers of a stellar envelope. We compare DES14X3taz to the few double-peaked SLSN-I events in the literature. Although the rise times and characteristics of these initial peaks differ, there exists the tantalizing possibility that they can be explained by one physical interpretation.« less

  16. Pentan isomers compound flame front structure

    SciTech Connect (OSTI)

    Mansurov, Z.A.; Mironenko, A.W.; Bodikov, D.U.; Rachmetkaliev, K.N.

    1995-08-13

    The fuels (hexane, pentane, diethyl ether) and conditions investigated in this study are relevant to engine knock in spark- ignition engines. A review is provided of the field of low temperature hydrocarbon oxidation. Studies were made of radical and stable intermediate distribution in the front of cool flames: Maximum concentrations of H atoms and peroxy radicals were observed in the luminous zone of the cool flame front. Peroxy radicals appear before the luminous zone at 430 K due to diffusion. H atoms were found in cool flames of butane and hexane. H atoms diffuses from the luminous zone to the side of the fresh mixture, and they penetrate into the fresh mixture to a small depth. Extension of action sphear of peroxy radicals in the fresh mixture is much greater than that of H atoms due to their small activity and high concentrations.

  17. New Efficiency Record Achieved for White OLED Device

    Broader source: Energy.gov [DOE]

    Osram Opto-Semiconductors, Inc. has successfully demonstrated a white organic light emitting diode (OLED) with a record efficiency of 25 lumens per watt, the highest known efficiency achieved to date for a polymer-based white OLED. The 25 LPW cool-white-emitting device was produced by applying a standard external inorganic phosphor to Osram's record-breaking blue-emitting phosphorescent polymer device with a peak luminous efficacy of 14 LPW.

  18. Measured daylighting potential of a static optical louver system under real sun and sky conditions

    SciTech Connect (OSTI)

    Konis, Kyle; Lee, Eleanor S.

    2015-05-04

    Side-by-side comparisons were made over solstice-to-solstice changes in sun and sky conditions between an optical louver system (OLS) and a conventional Venetian blind set at a horizontal slat angle and located inboard of a south-facing, small-area, clerestory window in a full-scale office testbed. Daylight autonomy (DA), window luminance, and ceiling luminance uniformity were used to assess performance. The performance of both systems was found to have significant seasonal variation, where performance under clear sky conditions improved as maximum solar altitude angles transitioned from solstice to equinox. Although the OLS produced fewer hours per day of DA on average than the Venetian blind, the OLS never exceeded the designated 2000 cd/m2 threshold for window glare. In contrast, the Venetian blind was found to exceed the visual discomfort threshold over a large fraction of the day during equinox conditions. Notably, these peak periods of visual discomfort occurred during the best periods of daylighting performance. Luminance uniformity was analyzed using calibrated high dynamic range luminance images. Under clear sky conditions, the OLS was found to increase the luminance of the ceiling as well as produce a more uniform distribution. Furthermore, compared to conventional venetian blinds, the static optical sunlight redirecting system studied has the potential to significantly reduce the annual electrical lighting energy demand of a daylit space and improve the quality from the perspective of building occupants by consistently transmitting useful daylight while eliminating window glare.

  19. Measured daylighting potential of a static optical louver system under real sun and sky conditions

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Konis, Kyle; Lee, Eleanor S.

    2015-05-04

    Side-by-side comparisons were made over solstice-to-solstice changes in sun and sky conditions between an optical louver system (OLS) and a conventional Venetian blind set at a horizontal slat angle and located inboard of a south-facing, small-area, clerestory window in a full-scale office testbed. Daylight autonomy (DA), window luminance, and ceiling luminance uniformity were used to assess performance. The performance of both systems was found to have significant seasonal variation, where performance under clear sky conditions improved as maximum solar altitude angles transitioned from solstice to equinox. Although the OLS produced fewer hours per day of DA on average than themore » Venetian blind, the OLS never exceeded the designated 2000 cd/m2 threshold for window glare. In contrast, the Venetian blind was found to exceed the visual discomfort threshold over a large fraction of the day during equinox conditions. Notably, these peak periods of visual discomfort occurred during the best periods of daylighting performance. Luminance uniformity was analyzed using calibrated high dynamic range luminance images. Under clear sky conditions, the OLS was found to increase the luminance of the ceiling as well as produce a more uniform distribution. Furthermore, compared to conventional venetian blinds, the static optical sunlight redirecting system studied has the potential to significantly reduce the annual electrical lighting energy demand of a daylit space and improve the quality from the perspective of building occupants by consistently transmitting useful daylight while eliminating window glare.« less

  20. LED Efficacy: What America Stands to Gain

    Broader source: Energy.gov (indexed) [DOE]

    diode) lighting technology have been realized in the past decade, as evidenced by the high-performing products now gaining share in growing numbers of lighting market ...

  1. Neurohumoral indicators of efficacy radiofrequency cardiac denervation

    SciTech Connect (OSTI)

    Evtushenko, A. V. Evtushenko, V. V.; Saushkina, Yu. V.; Gusakova, A. M.; Suslova, T. E.; Dymbrylova, O. N.; Smyshlyaev, K. A.; Kurlov, I. O.; Lishmanov, Yu. B.; Anfinogenova, Ya. D.; Sergeevichev, D. S.; Bykov, A. N.; Syryamkin, V. I.; Kistenev, Yu. V.; Lotkov, A. I.; Pokushalov, E. A.

    2015-11-17

    In this study, we compared pre- and postoperative parameters of the cardiac sympathetic innervation. The aim of the study was to examine the approaches to evaluating the quality of radiofrequency (RF)-induced cardiac denervation by using non-invasive and laboratory methods. The study included 32 people with long-lasting persistent atrial fibrillation (AF). The patients were divided into 2 groups according to the objectives of the study: group 1 (main) - 21 patients with mitral valve diseases, which simultaneously with radiofrequency ablation (RFA) AF carried out on the effects of the paraganglionic nervous plexuses by C. Pappone (2004) and N. Doll (2008) schemes. The second group (control) contained 11 patients with heart diseases in sinus rhythm (the RF denervation not been performed). All patients, who underwent surgical treatment, were received examination of cardiac sympathetic tone by using {sup 123}I-MIBG. All of them made blood analysis from ascending aorta and coronary sinus to determine the level of norepinephrine and its metabolites before and after cardiac denervation. Data of radionuclide examination are correlating with laboratory data.

  2. CALiPER Report 21.1. Linear (T8) Lamps in a 2x4 K12-Lensed Troffer

    SciTech Connect (OSTI)

    2014-04-01

    This report focuses on the performance of the same 31 linear LED lamps operated in a typical troffer with a K12 prismatic lens. In general, luminaire efficacy is strongly dictated by lamp efficacy, but the optical system of the luminaire substantially reduces the differences between the luminous intensity distributions of the lamps. While the distributions in the luminaire are similar, the differences remain large enough that workplane illuminance uniformity may be reduced if linear LED lamps with a narrow distribution are used. At the same time, linear LED lamps with a narrower distribution result in slightly higher luminaire efficiency.

  3. An evaluation of the maximum tag burden for implantation of acoustic transmitters in juvenile Chinook salmon

    SciTech Connect (OSTI)

    Brown, Richard S.; Harnish, Ryan A.; Carter, Kathleen M.; Boyd, James W.; Deters, Katherine A.; Eppard, M. B.

    2010-04-01

    Abstract.—The influence of a surgically implanted acoustic micro-transmitter and passive integrated transponder (PIT) tag on the growth and survival of hatchery-reared juvenile Chinook salmon was examined. Growth and survival were compared between treatment (implanted) and control fish within three fork length (FL) size groups (80-89, 90-99, and 100-109 mm). The acoustic micro-transmitter and PIT tag implanted in our study had a combined weight of 0.74 g. Weights of study fish ranged from 4.7 to 16.3 g for treatment fish and from 5.1 to 16.8 g for control fish. The burden for the combined acoustic and PIT tag experienced by implanted fish ranged from 8.8% to 15.7% for the 80-89 mm FL group, 6.0-10.9% for the 90-99 mm FL group, and 4.5-8.6% for the 100-109 mm FL group. Results indicated that growth and survival were size-dependent among implanted juvenile Chinook salmon. Significant differences in growth rate and survival were observed between treatment and control fish in the 80-89 mm FL group. Within this group, growth of fish smaller than 88.5 mm FL (tag burden > 10.0%) was negatively affected by the implantation or presence of an acoustic micro-transmitter and PIT tag. Survival of fish in the 90-99 mm FL group did not differ between treatment and control fish. However, survival of implanted fish within this size group that were smaller than 97.2 mm FL (tag burden > 7.4%) was negatively influenced. These results indicate that the burden of an acoustic micro-transmitter and PIT tag should be maintained at or below about 7.0% for studies that use hatchery-reared juvenile Chinook salmon.

  4. EERE Takes Important Steps to Ensure Maximum Impact of Technology Program Investments

    Broader source: Energy.gov [DOE]

    The Office of Energy Efficiency and Renewable Energy (EERE) is at the center of creating the clean energy economy today, developing and delivering market-driven solutions for energy-saving homes, buildings, and manufacturing; sustainable transportation; and renewable electricity generation. Such a large and critical goal requires EERE to leverage a number of management techniques and tools to ensure taxpayer-funded investments are directed to achieve the intended high value impact. One such tool is to perform “retrospective impact analysis,” effectively looking backwards over time and assessing how EERE has accelerated development and commercialization of technologies and produced a return on public investment that contributes to the nation’s economic growth.

  5. The use of experimental design to find the operating maximum power point of PEM fuel cells

    SciTech Connect (OSTI)

    Crăciunescu, Aurelian; Pătularu, Laurenţiu; Ciumbulea, Gloria; Olteanu, Valentin; Pitorac, Cristina; Drugan, Elena

    2015-03-10

    Proton Exchange Membrane (PEM) Fuel Cells are difficult to model due to their complex nonlinear nature. In this paper, the development of a PEM Fuel Cells mathematical model based on the Design of Experiment methodology is described. The Design of Experiment provides a very efficient methodology to obtain a mathematical model for the studied multivariable system with only a few experiments. The obtained results can be used for optimization and control of the PEM Fuel Cells systems.

  6. NONLINEAR DEVELOPMENT OF THE R-MODE INSTABILITY AND THE MAXIMUM ROTATION RATE OF NEUTRON STARS

    SciTech Connect (OSTI)

    Bondarescu, Ruxandra; Wasserman, Ira E-mail: ira@astro.cornell.edu

    2013-11-20

    We describe how the nonlinear development of the R-mode instability of neutron stars influences spin up to millisecond periods via accretion. When nearly resonant interactions of the l = m = 2 R-mode with pairs of 'daughter modes' are included, the R-mode saturates at the lowest amplitude which leads to significant excitation of a pair of modes. The lower bound for this threshold amplitude is proportional to the damping rate of the particular daughter modes that are excited parametrically. We show that if dissipation occurs in a very thin boundary layer at the crust-core boundary, the R-mode saturation amplitude is too large for angular momentum gain from accretion to overcome loss to gravitational radiation. We find that lower dissipation is required to explain spin up to frequencies much higher than 300 Hz. We conjecture that if the transition from the fluid core to the crystalline crust occurs over a distance much longer than 1 cm, then a sharp viscous boundary layer fails to form. In this case, damping is due to shear viscosity dissipation integrated over the entire star. We estimate the lowest parametric instability threshold from first principles. The resulting saturation amplitude is low enough to permit spin up to higher frequencies. The requirement to allow continued spin up imposes an upper bound to the frequencies attained via accretion that plausibly may be about 750 Hz. Within this framework, the R-mode is unstable for all millisecond pulsars, whether accreting or not.

  7. MILLISECOND PULSAR AGES: IMPLICATIONS OF BINARY EVOLUTION AND A MAXIMUM SPIN LIMIT

    SciTech Connect (OSTI)

    Kiziltan, Buelent; Thorsett, Stephen E., E-mail: bulent@astro.ucsc.ed [Department of Astronomy and Astrophysics, University of California and UCO/Lick Observatory, Santa Cruz, CA 95064 (United States)

    2010-05-20

    In the absence of constraints from the binary companion or supernova remnant, the standard method for estimating pulsar ages is to infer an age from the rate of spin-down. While the generic spin-down age may give realistic estimates for normal pulsars, it can fail for pulsars with very short periods. Details of the spin-up process during the low-mass X-ray binary (LMXB) phase pose additional constraints on the period (P) and spin-down rates ( P-dot ) that may consequently affect the age estimate. Here, we propose a new recipe to estimate millisecond pulsar (MSP) ages that parametrically incorporates constraints arising from binary evolution and limiting physics. We show that the standard method can be improved by this approach to achieve age estimates closer to the true age while the standard spin-down age may overestimate or underestimate the age of the pulsar by more than a factor of {approx}10 in the millisecond regime. We use this approach to analyze the population on a broader scale. For instance, in order to understand the dominant energy loss mechanism after the onset of radio emission, we test for a range of plausible braking indices. We find that a braking index of n = 3 is consistent with the observed MSP population. We demonstrate the existence and quantify the potential contributions of two main sources of age corruption: the previously known 'age bias' due to secular acceleration and 'age contamination' driven by sub-Eddington progenitor accretion rates. We explicitly show that descendants of LMXBs that have accreted at very low rates ( m-dot << M-dot{sub Edd}) will exhibit ages that appear older than the age of the Galaxy. We further elaborate on this technique, the implications and potential solutions it offers regarding MSP evolution, the underlying age distribution, and the post-accretion energy loss mechanism.

  8. Physiological and growth responses of C3 and C4 plants at the Pleistocene glacial maximum

    SciTech Connect (OSTI)

    Strain, B.R.

    1995-06-01

    A C3 plant (Abutilon theophrasti) and a C4 plant (Amaranthus retroflexus) were grown from seed in the Duke University Phytotron under four CO2 concentrations (15 Pa, below the Pleistocene minimum), 27 Pa (pre-industrial), 35 Pa (current), and 70 Pa (future) to examine photosynthetic, growth and reproduction responses of annual plants to historic and future levels of CO2. Net photosynthesis and growth were greatly inhibited at 15 Pa and greatly stimulated at 70 Pa. in the C3 Abutilon but only slightly affected in the C4 Amaranthus. Flower bud initiation was not affected by CO2 treatment in either species but all flower buds in 15 Pa CO2 aborted in the C3 within two days of appearance while no inhibition of reproduction was observed at low CO2 in the C4. Differences in physiology, growth and reproduction to the low levels of atmospheric CO2 of the Pleistocene suggest that competitive interactions of C3 and C4 annuals have changed through geologic time. A major question concerning the survival and evolution of obligate C3 annuals during the CO2 minima of the Pleistocene is raised by the results of this study.

  9. U.S. Lower 48 States Offshore Maximum Number of Active Crews Engaged in

    Gasoline and Diesel Fuel Update (EIA)

    Foot) Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2012 NA NA NA NA NA NA NA NA NA NA NA NA 2013 1,026 1,026 1,026 1,026 1,027 1,027 1,027 1,027 1,027 1,027 1,028 1,028 2014 1,029 1,028 1,029 1,029 1,030 1,030 1,032 1,033 1,033 1,033 1,034 1,035 2015 1,036 1,036 1,036 1,037 1,037 1,037 1,037 1,036 1,037 1,037 1,038 1,038 2016 1,038 1,038 1,037 1,037 1,034 1,034

    Imputed Value of Natural Gas Market Production (Cost) U.S. Imputed Value of Natural Gas Market Production (Cost) Decade

  10. U.S.Lower 48 States Offshore Maximum Number of Active Crews Engaged in

    Gasoline and Diesel Fuel Update (EIA)

    Feet) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 2000's 4,211,193 4,327,844 2010's 4,410,224 4,483,650 4,576,356 4,748,636 4,785,669 Cubic Feet)

    Acquifers Capacity (Million Cubic Feet) U.S. Working Natural Gas Underground Storage Acquifers Capacity (Million Cubic Feet) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 2000's 396,950 396,092 2010's 364,228 363,521 367,108 453,054 452,044 - = No Data Reported; -- = Not

  11. Alaska Maximum Number of Active Crews Engaged in Four-Dimensional Seismic

    Gasoline and Diesel Fuel Update (EIA)

    Jan-16 Feb-16 Mar-16 Apr-16 May-16 Jun-16 View History Delivered to Consumers 1,000 1,000 1,001 1,001 1,002 1,003 2013-2016

    0 0 36 16 0 2 1979-2014 Adjustments 0 0 1 0 0 0 2009-2014 Revision Increases 0 0 55 0 0 1 2009-2014 Revision Decreases 0 0 0 0 0 0 2009-2014 Sales 0 0 0 0 0 0 2009-2014 Acquisitions 0 0 0 0 0 1 2009-2014 Extensions 0 0 0 0 0 0 2009-2014 New Field Discoveries 0 0 0 0 0 0 2009-2014 New Reservoir Discoveries in Old Fields 0 0 0 0 0 0 2009-2014 Estimated Production 0 0 20 20

  12. Alaska Maximum Number of Active Crews Engaged in Seismic Surveying (Number

    Gasoline and Diesel Fuel Update (EIA)

    of Elements) Seismic Surveying (Number of Elements) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 2000's 13 4 23 12

  13. Alaska Maximum Number of Active Crews Engaged in Three-Dimensional Seismic

    Gasoline and Diesel Fuel Update (EIA)

    Surveying (Number of Elements) Three-Dimensional Seismic Surveying (Number of Elements) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 2000's 9 2 11 6

  14. Alaska Maximum Number of Active Crews Engaged in Two-Dimensional Seismic

    Gasoline and Diesel Fuel Update (EIA)

    Surveying (Number of Elements) Two-Dimensional Seismic Surveying (Number of Elements) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 2000's 4 2 12 6 0 0 0 0 NA 0 2010's 0

  15. Optimizing cellulase mixtures for maximum rate and extent of hydrolysis. Final report

    SciTech Connect (OSTI)

    Walker, L.P.; Wilson, D.B.

    1997-03-01

    Pure Thomomonospora fusca and Trichoderma reesei cellulases and their mixtures were studied to determine the optimal set of cellulases for biomass hydrolysis. The objective was to reduce the cost of cellulase in order to help lower the overall processing cost of the enzymatic conversion of biomass cellulose to sugars, which can then be fermented into fuels and other energy-intensive chemicals. No cellulase mixture was obtained that was much better than the best commercially available preparations. However, the study has greatly increased knowledge of T. fusca cellulases, synergism, and cellulose binding, and provide evidence that future work will produce cellulases with higher activity in degrading crystalline cellulose. T. fusca cellulases may have good industrial potential because: (1) they are compatible with industrial processes that operate at elevated temperatures; (2) they retain 90% of their activity under neutral or basic conditions, which provides a great deal of flexibility in reactor design and operation; and (3) tools are now available to change specific amino acid residues in their catalytic domains and to assess how these changes influence catalysis. 74 refs.

  16. Indirectly sensing accelerator beam currents for limiting maximum beam current magnitude

    DOE Patents [OSTI]

    Bogaty, J.M.; Clifft, B.E.; Bollinger, L.M.

    1995-08-08

    A beam current limiter is disclosed for sensing and limiting the beam current in a particle accelerator, such as a cyclotron or linear accelerator, used in scientific research and medical treatment. A pair of independently operable capacitive electrodes sense the passage of charged particle bunches to develop an RF signal indicative of the beam current magnitude produced at the output of a bunched beam accelerator. The RF signal produced by each sensing electrode is converted to a variable DC voltage indicative of the beam current magnitude. The variable DC voltages thus developed are compared to each other to verify proper system function and are further compared to known references to detect beam currents in excess of pre-established limits. In the event of a system malfunction, or if the detected beam current exceeds pre-established limits, the beam current limiter automatically inhibits further accelerator operation. A high Q tank circuit associated with each sensing electrode provides a narrow system bandwidth to reduce noise and enhance dynamic range. System linearity is provided by injecting, into each sensing electrode, an RF signal that is offset from the bunching frequency by a pre-determined beat frequency to ensure that subsequent rectifying diodes operate in a linear response region. The system thus provides a large dynamic range in combination with good linearity. 6 figs.

  17. Indirectly sensing accelerator beam currents for limiting maximum beam current magnitude

    DOE Patents [OSTI]

    Bogaty, John M.; Clifft, Benny E.; Bollinger, Lowell M.

    1995-01-01

    A beam current limiter for sensing and limiting the beam current in a particle accelerator, such as a cyclotron or linear accelerator, used in scientific research and medical treatment. A pair of independently operable capacitive electrodes sense the passage of charged particle bunches to develop an RF signal indicative of the beam current magnitude produced at the output of a bunched beam accelerator. The RF signal produced by each sensing electrode is converted to a variable DC voltage indicative of the beam current magnitude. The variable DC voltages thus developed are compared to each other to verify proper system function and are further compared to known references to detect beam currents in excess of pre-established limits. In the event of a system malfunction, or if the detected beam current exceeds pre-established limits, the beam current limiter automatically inhibits further accelerator operation. A high Q tank circuit associated with each sensing electrode provides a narrow system bandwidth to reduce noise and enhance dynamic range. System linearity is provided by injecting, into each sensing electrode, an RF signal that is offset from the bunching frequency by a pre-determined beat frequency to ensure that subsequent rectifying diodes operate in a linear response region. The system thus provides a large dynamic range in combination with good linearity.

  18. Extracting maximum petrophysical and geological information from a limited reservoir database

    SciTech Connect (OSTI)

    Ali, M.; Chawathe, A.; Ouenes, A.

    1997-08-01

    The characterization of old fields lacking sufficient core and log data is a challenging task. This paper describes a methodology that uses new and conventional tools to build a reliable reservoir model for the Sulimar Queen field. At the fine scale, permeability measured on a fine grid with a minipermeameter was used in conjunction with the petrographic data collected on multiple thin sections. The use of regression analysis and a newly developed fuzzy logic algorithm led to the identification of key petrographic elements which control permeability. At the log scale, old gamma ray logs were first rescaled/calibrated throughout the entire field for consistency and reliability using only four modem logs. Using data from one cored well and the rescaled gamma ray logs, correlations between core porosity, permeability, total water content and gamma ray were developed to complete the small scale characterization. At the reservoir scale, outcrop data and the rescaled gamma logs were used to define the reservoir structure over an area of ten square miles where only 36 wells were available. Given the structure, the rescaled gamma ray logs were used to build the reservoir volume by identifying the flow units and their continuity. Finally, history-matching results constrained to the primary production were used to estimate the dynamic reservoir properties such as relative permeabilities to complete the characterization. The obtained reservoir model was tested by forecasting the waterflood performance and which was in good agreement with the actual performance.

  19. Alaska Maximum Number of Active Crews Engaged in Four-Dimensional...

    Gasoline and Diesel Fuel Update (EIA)

    Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2000 NA NA 0 0 0 0 0 0 0 0 0 0 2001 0 0 0 0 0 0 0 0 0 0 0 0 2002 0 0 0 0 0 0 0 0 0 0 0 0 2003 0 0 0 0 0 0 0 0 0 0 0 0 2004 0 0...

  20. U.S.Lower 48 States Offshore Maximum Number of Active Crews Engaged...

    Gasoline and Diesel Fuel Update (EIA)

    Two-Dimensional Seismic Surveying (Number of Elements) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 2000's 69 98 105 81 47 72 52 40 NA 36 2010's 52...

  1. U.S.Lower 48 States Onshore Maximum Number of Active Crews Engaged...

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    Two-Dimensional Seismic Surveying (Number of Elements) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 2000's 40 78 96 90 101 87 59 40 NA 21 2010's 13...

  2. U.S.Lower 48 States Onshore Maximum Number of Active Crews Engaged...

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    Four-Dimensional Seismic Surveying (Number of Elements) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 2000's 10 12 0 1 0 0 0 0 NA 0 2010's 0...

  3. U.S.Lower 48 States Onshore Maximum Number of Active Crews Engaged...

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    Three-Dimensional Seismic Surveying (Number of Elements) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 2000's 383 422 320 252 354 424 541 667 NA 642...

  4. U.S.Lower 48 States Offshore Maximum Number of Active Crews Engaged...

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    Three-Dimensional Seismic Surveying (Number of Elements) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 2000's 88 101 79 45 47 61 64 83 NA 87 2010's...

  5. U.S.Lower 48 States Offshore Maximum Number of Active Crews Engaged...

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    Four-Dimensional Seismic Surveying (Number of Elements) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 2000's 0 0 0 0 0 0 0 9 NA 0 2010's 0...

  6. A reassessment of surface friction model for maximum cold fusion reactions in superheavy mass region

    SciTech Connect (OSTI)

    Fukushima, A.; Wada, T.; Ohta, M.; Nasirov, A.; Aritomo, Y.

    2007-02-26

    We have made a study on the capture process of 40,48Ca+ 208Pb systems with a dynamical approach based on the surface friction model. The deformation of the nuclei due to the mutual excitation is taken into account. We have calculated the capture cross sections for several values of the friction coefficients. It was shown that, in the cold fusion reactions, the friction parameters of the surface friction model needs to be reexamined.

  7. Classification of Distributed Data Using Topic Modeling and Maximum Variation Sampling

    SciTech Connect (OSTI)

    Patton, Robert M; Beaver, Justin M; Potok, Thomas E

    2011-01-01

    From a management perspective, understanding the information that exists on a network and how it is distributed provides a critical advantage. This work explores the use of topic modeling as an approach to automatically determine the classes of information that exist on an organization's network, and then use the resultant topics as centroid vectors for the classification of individual documents in order to understand the distribution of information topics across the enterprise network. The approach is tested using the 20 Newsgroups dataset.

  8. Estimate of Maximum Underground Working Gas Storage Capacity in the United States: 2007 Update

    Reports and Publications (EIA)

    2007-01-01

    This report provides an update to an estimate for U.S. aggregate natural gas storage capacity that was released in 2006.

  9. Leveraging Limited Scope for Maximum Benefit in Occupied Renovation of Uninsulated Cold Climate Multifamily Housing

    SciTech Connect (OSTI)

    Neuhauser, K.; Bergey, D.; Osser, R.

    2012-03-01

    This project examines a large-scale renovation project within a 500 unit, 1960's era subsidized urban housing community. This research focuses on the airflow control and window replacement measures implemented as part of the renovations to the low-rise apartment buildings. The window replacement reduced the nominal conductive loss of the apartment enclosure by approximately 15%; air sealing measures reduced measured air leakage by approximately 40% on average.

  10. Sanduleak's Star (LMC Anonymous) - Its similarity in the far-ultraviolet with the luminous object Eta Carinae and SN 1987A

    SciTech Connect (OSTI)

    Michalitsianos, A.G.; Kafatos, M.; Shore, S.N.; George Mason Univ., Fairfax, VA; New Mexico Institute of Mining and Technology, Socorro )

    1989-06-01

    Low-resolution IUE SWP spectra of the peculiar object LMC Anonymous (Sanduleak's Star) indicates strong evidence for CNO-processed nebula in the vicinity of the star. The far-UV spectrum of LMC Anonymous closely resembles that of the S Condensation of Eta Carinae. The similarity between LMC Anonymous and the S Condensation is apparent from the absolute intensity of the N V, semiforbidden N IV, and semiforbidden N III emission lines compared with the reduced strength of C IV or semiforbidden C III emission. IUE spectra of the S Condensation and SN 1987A may provide important clues concerning the nature of LMC Anonymous, which indicates departures from normal cosmic abundances of nitrogen relative to carbon that are extreme. This may suggest that carbon envelope burning and dredge-up occurred simultaneously during the helium-burning stage. 25 refs.

  11. NEW SPATIALLY RESOLVED MID-INFRARED OBSERVATIONS OF THE TRANSITIONAL DISK TW Hya AND TENTATIVE EVIDENCE FOR A SELF-LUMINOUS COMPANION

    SciTech Connect (OSTI)

    Arnold, Timothy J.; Eisner, J. A.; Monnier, J. D.; Tuthill, Peter E-mail: jeisner@email.arizona.edu E-mail: p.tuthill@physics.usyd.edu.au

    2012-05-10

    We present spatially resolved observations of the canonical transition disk object TW Hya at 8.74 {mu}m, 11.66 {mu}m, and 18.30 {mu}m, obtained with the T-ReCS instrument on the Gemini telescope. These observations are a result of a novel observing mode at Gemini that enables speckle imaging. Using this technique, we image our target with short enough exposure times to achieve diffraction limited images. We use Fourier techniques to reduce our data, which allows high-precision calibration of the instrumental point-spread function. Our observations span two epochs and we present evidence for temporal variability at 11.66 {mu}m in the disk of TW Hya. We show that previous models of TW Hya's disk from the literature are incompatible with our observations and construct a model to explain the discrepancies. We detect marginal asymmetry in our data, most significantly at the shortest wavelengths. To explain our data, we require a model that includes an optically thin inner disk extending from 0.02 to 3.9 AU, an optically thick ring representing the outer disk wall at 3.9 AU and extending to 4.6 AU, and a hotter-than-disk-equilibrium source of emission located at {approx}3.5 AU.

  12. HerMES: The rest-frame UV emission and a lensing model for the z = 6.34 luminous dusty starburst galaxy HFLS3

    SciTech Connect (OSTI)

    Cooray, Asantha; Calanog, Jae; Casey, C. M.; Ma, Brian; Osage, W. A.; Wardlow, Julie L.; Bock, J.; Bridge, C.; Burgarella, D.; Bussmann, R. S.; Clements, D.; Conley, A.; Farrah, D.; Fu, H.; Gavazzi, R.; Ivison, R. J.; La Porte, N.; Lo Faro, B.; Magdis, G.; Oliver, S. J.; and others

    2014-07-20

    We discuss the rest-frame ultraviolet emission from the starbursting galaxy HFLS3 at a redshift of 6.34. The galaxy was discovered in Herschel/SPIRE data due to its red color in the submillimeter wavelengths from 250 to 500 ?m. Keck/NIRC2 K{sub s}-band adaptive optics imaging data showed two potential near-IR counterparts near HFLS3. Previously, the northern galaxy was taken to be in the foreground at z = 2.1, while the southern galaxy was assumed to be HFLS3's near-IR counterpart. The recently acquired Hubble/WFC3 and Advanced Camera for Surveys (ACS) imaging data show conclusively that both optically bright galaxies are in the foreground at z < 6. A new lensing model based on the Hubble imaging data and the millimeter-wave continuum emission yields a magnification factor of 2.2 0.3, with a 95% confidence upper limit on the magnification of 3.5. When corrected for lensing, the instantaneous star formation rate is 1320 M{sub ?} yr{sup 1}, with the 95% confidence lower limit around 830 M{sub ?} yr{sup 1}. The dust and stellar masses of HFLS3 from the same spectral energy distribution (SED) models are at the level of 3 10{sup 8} M{sub ?} and ?5 10{sup 10} M{sub ?}, respectively, with large systematic uncertainties on assumptions related to the SED model. With Hubble/WFC3 images, we also find diffuse near-IR emission about 0.5 arcsec (?3 kpc) to the southwest of HFLS3 that remains undetected in the ACS imaging data. The emission has a photometric redshift consistent with either z ? 6 or a dusty galaxy template at z ? 2.

  13. THE COSMOLOGICAL IMPACT OF LUMINOUS TeV BLAZARS. I. IMPLICATIONS OF PLASMA INSTABILITIES FOR THE INTERGALACTIC MAGNETIC FIELD AND EXTRAGALACTIC GAMMA-RAY BACKGROUND

    SciTech Connect (OSTI)

    Broderick, Avery E.; Chang, Philip; Pfrommer, Christoph E-mail: pchang@cita.utoronto.ca

    2012-06-10

    Inverse Compton cascades (ICCs) initiated by energetic gamma rays (E {approx}> 100 GeV) enhance the GeV emission from bright, extragalactic TeV sources. The absence of this emission from bright TeV blazars has been used to constrain the intergalactic magnetic field (IGMF), and the stringent limits placed on the unresolved extragalactic gamma-ray background (EGRB) by Fermi have been used to argue against a large number of such objects at high redshifts. However, these are predicated on the assumption that inverse Compton scattering is the primary energy-loss mechanism for the ultrarelativistic pairs produced by the annihilation of the energetic gamma rays on extragalactic background light photons. Here, we show that for sufficiently bright TeV sources (isotropic-equivalent luminosities {approx}> 10{sup 42} erg s{sup -1}) plasma beam instabilities, specifically the 'oblique' instability, present a plausible mechanism by which the energy of these pairs can be dissipated locally, heating the intergalactic medium. Since these instabilities typically grow on timescales short in comparison to the inverse Compton cooling rate, they necessarily suppress the ICCs. As a consequence, this places a severe constraint on efforts to limit the IGMF from the lack of a discernible GeV bump in TeV sources. Similarly, it considerably weakens the Fermi limits on the evolution of blazar populations. Specifically, we construct a TeV-blazar luminosity function from those objects currently observed and find that it is very well described by the quasar luminosity function at z {approx} 0.1, shifted to lower luminosities and number densities, suggesting that both classes of sources are regulated by similar processes. Extending this relationship to higher redshifts, we show that the magnitude and shape of the EGRB above {approx}10 GeV are naturally reproduced with this particular example of a rapidly evolving TeV-blazar luminosity function.

  14. MOF Coating a Promising Path to White LEDs

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    MOF Coating a Promising Path to White LEDs MOF Coating a Promising Path to White LEDs Print Friday, 27 February 2015 17:11 Hu et al. designed a new yellow phosphor with high quantum yield by immobilizing a preslected chromophore into the rigid framework of a metal-organic framework (MOF); the structure was determined at Beamline 11.3.1. Coating a blue light-emitting diode (LED) with this compound readily generates white light with high luminous efficacy. The new yellow phosphor demonstrates

  15. Comparison of light out-coupling enhancements in single-layer blue-phosphorescent organic light emitting diodes using small-molecule or polymer hosts

    SciTech Connect (OSTI)

    Chang, Yung-Ting; Liu, Shun-Wei; Yuan, Chih-Hsien; Lee, Chih-Chien; Ho, Yu-Hsuan; Wei, Pei-Kuen; Chen, Kuan-Yu; Lee, Yi-Ting; Wu, Min-Fei; Chen, Chin-Ti E-mail: chihiwu@cc.ee.ntu.edu.tw; Wu, Chih-I E-mail: chihiwu@cc.ee.ntu.edu.tw

    2013-11-07

    Single-layer blue phosphorescence organic light emitting diodes (OLEDs) with either small-molecule or polymer hosts are fabricated using solution process and the performances of devices with different hosts are investigated. The small-molecule device exhibits luminous efficiency of 14.7?cd/A and maximum power efficiency of 8.39?lm/W, which is the highest among blue phosphorescence OLEDs with single-layer solution process and small molecular hosts. Using the same solution process for all devices, comparison of light out-coupling enhancement, with brightness enhancement film (BEF), between small-molecule and polymer based OLEDs is realized. Due to different dipole orientation and anisotropic refractive index, polymer-based OLEDs would trap less light than small molecule-based OLEDs internally, about 37% better based simulation results. In spite of better electrical and spectroscopic characteristics, including ambipolar characteristics, higher carrier mobility, higher photoluminescence quantum yield, and larger triplet state energy, the overall light out-coupling efficiency of small molecule-based devices is worse than that of polymer-based devices without BEF. However, with BEF for light out-coupling enhancement, the improved ratio in luminous flux and luminous efficiency for small molecule based device is 1.64 and 1.57, respectively, which are significantly better than those of PVK (poly-9-vinylcarbazole) devices. In addition to the theoretical optical simulation, the experimental data also confirm the origins of differential light-outcoupling enhancement. The maximum luminous efficiency and power efficiency are enhanced from 14.7?cd/A and 8.39?lm/W to 23?cd/A and 13.2?lm/W, respectively, with laminated BEF, which are both the highest so far for single-layer solution-process blue phosphorescence OLEDs with small molecule hosts.

  16. High Efficacy Green LEDs by Polarization Controlled MOVPE

    SciTech Connect (OSTI)

    Wetzel, Christian

    2013-03-31

    Amazing performance in GaInN/GaN based LEDs has become possible by advanced epitaxial growth on a wide variety of substrates over the last decade. An immediate push towards product development and worldwide competition for market share have effectively reduced production cost and generated substantial primary energy savings on a worldwide scale. At all times of the development, this economic pressure forced very fundamental decisions that would shape huge industrial investment. One of those major aspects is the choice of epitaxial growth substrate. The natural questions are to what extend a decision for a certain substrate will limit the ultimate performance and to what extent, the choice of a currently more expensive substrate such as native GaN could overcome any of the remaining performance limitations. Therefore, this project has set out to explore what performance characteristic could be achieved under the utilization of bulk GaN substrate. Our work was guided by the hypotheses that line defects such as threading dislocations in the active region should be avoided and the huge piezoelectric polarization needs to be attenuated if not turned off for higher performing LEDs, particularly in the longer wavelength green and deep green portions of the visible spectrum. At their relatively lower performance level, deep green LEDs are a stronger indicator of relative performance improvements and seem particular sensitive to the challenges at hand. The project therefore made use of recently developed non-polar and semipolar bulk GaN substrates that were made available at Kyma Technologies by crystallographic cuts from thick polar growth of GaN. This approach naturally leads to rather small pieces of substrates, cm along the long side while mm along the short one. Small size and limited volume of sample material therefore set the limits of the ensuing development work. During the course of the project we achieved green and deep green LEDs in all those crystal growth orientations: polar c-plane, non- polar a-plane, non-polar m-plane, and semipolar planes. The active region in those structures shows dramatically reduced densities of threading dislocations unless the wavelength was extended as far as 510 nm and beyond. With the appearance of such defects, the light output power dropped precipitously supporting the necessity to avoid any and all of such defects to reach the active region. Further aspects of the non-polar growth orientation proved extremely promising for the development of such structures. Chief among them is our success to achieve extremely uniform quantum wells in these various crystal orientations that prove devoid of any alloy fluctuation beyond the theoretical limit of a binominal distribution. This became very Rensselaer Wetzel DE?EE0000627 3 directly apparent in highly advanced atom probe tomography performed in collaboration at Northwestern University. Furthermore, under reduced or absence of piezoelectric polarization, green emitters in those growth geometries exhibit an unsurpassed wavelength stability over very wide excitation and drive current ranges. Such a performance had not been possible in any polar c-plane growth and now places green LEDs in terms of wavelength stability up par with typical 450 nm blue emitters. The project also incorporated enabling opportunities in the development of micro and nano- patterned substrate technologies. Originally developped as a means to enhance generated light extraction we have demonstrated that the method of nano-patterning, in contrast to micro- patterning also results in a substantial reduction of threading dislocation generation. In green LEDs, we thereby see equal contributions of enhanced light extraction and reduced defect generation to a threefold enhancement of the green light output power. These results have opened entirely new approaches for future rapid and low cost epitaxial material development by avoidance of thick defect accommodation layers. All methods developed within this project have meanwhile widely been publicized by the members o

  17. Wavefront Correction Efficacy : Comparing Arrays of 1-Actuator...

    Office of Scientific and Technical Information (OSTI)

    for presentation at the Adaptive Optics, Analysis and Methods sponsored by OSA held June 6-9, 2005 in Charlotte, NC. Research Org: Sandia National Laboratories (SNL-NM), ...

  18. Evaluation Of Shielding Efficacy Of A Ferrite Containing Ceramic Material

    SciTech Connect (OSTI)

    Verst, C.

    2015-10-12

    The shielding evaluation of the ferrite based Mitsuishi ceramic material has produced for several radiation sources and possible shielding sizes comparative dose attenuation measurements and simulated projections. High resolution gamma spectroscopy provided uncollided and scattered photon spectra at three energies, confirming theoretical estimates of the ceramic’s mass attenuation coefficient, μ/ρ. High level irradiation experiments were performed using Co-60, Cs-137, and Cf-252 sources to measure penetrating dose rates through steel, lead, concrete, and the provided ceramic slabs. The results were used to validate the radiation transport code MCNP6 which was then used to generate dose rate attenuation curves as a function of shielding material, thickness, and mass for photons and neutrons ranging in energy from 200 keV to 2 MeV.

  19. The Efficacy of Galaxy Shape Parameters in Photometric Redshift...

    Office of Scientific and Technical Information (OSTI)

    GENERAL PHYSICS; MORPHOLOGY; NEURAL NETWORKS; SHAPE; GALAXIES; PARAMETRIC ANALYSIS; RED SHIFT Astrophysics,ASTRO Word Cloud More Like This Full Text preview image File size N...

  20. Very high efficacy electrodeless high intensity discharge lamps

    DOE Patents [OSTI]

    Johnson, Peter D.

    1987-01-01

    An electrodeless arc lamp comprises an outer jacket hermetically sealing and thermally protecting an arc tube inside which has an upwardly convex bottom center section. The absence of chemically reactive electrode material makes it possible to use metal halides other than iodides. The tube contains chlorides, bromides or a mixture thereof of scandium and sodium in a nearly equimolar relationship in addition to mercury and an inert gas. Good color balance can be obtained at reduced reservoir temperature and with less power loss. Reduction in wall temperature makes it possible to attain longer lamp life.

  1. SSL Pricing and Efficacy Trend Analysis for Utility Program Planning

    SciTech Connect (OSTI)

    Tuenge, J. R.

    2013-10-01

    Report to help utilities and energy efficiency organizations forecast the order in which important SSL applications will become cost-effective and estimate when each "tipping point" will be reached. Includes performance trend analysis from DOE's LED Lighting Facts® and CALiPER programs plus cost analysis from various sources.

  2. Molecule Nanoweaver Improves Drug Delivery and Treatment Efficacy...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    along the synthetic route by using the powerful tool of solid-state NMR analyses. Upon development of a mature protocol, the Molecule Nanoweaver would operate on an assembly...

  3. The Efficacy of Radiotherapy in the Treatment of Orbital Pseudotumor

    SciTech Connect (OSTI)

    Matthiesen, Chance; Bogardus, Carl; Thompson, J. Spencer; Farris, Bradley; Hildebrand, Lloyd; Wilkes, Byron; Syzek, Elizabeth; Algan, Ozer; Ahmad, Salahuddin; Herman, Terence

    2011-04-01

    Purpose: To review institutional outcomes for patients treated with external-beam radiotherapy (EBRT) for orbital pseudotumor. Methods and Materials: This is a single-institution retrospective review of 20 orbits in 16 patients diagnosed with orbital pseudotumor that received EBRT at the University of Oklahoma, Department of Radiation Oncology. Treated patients had a median follow-up of 16.5 months. Results: Fifteen patients (93.7%) were initially treated with corticosteroids. Eight had recurrence after steroid cessation, six were unable to taper corticosteroids completely or partially, and one experienced progression of symptoms despite corticosteroid therapy. Fourteen patients (87.5%) initially responded to radiotherapy indicated by clinical improvement of preradiation symptoms and/or tapering of corticosteroid dose. Mean EBRT dose was 20 Gy (range, 14-30 Gy). Thirteen patients (81.2%) continued to improve after radiation therapy. Patient outcomes were complete cessation of corticosteroid therapy in nine patients (56.3%) and reduced corticosteroid dose in four patients (25%). Radiotherapy did not achieve long-term control for three patients (18.7%), who still required preradiation corticosteroid dosages. Three patients received retreatment(s) of four orbits, of which two patients achieved long-term symptom control without corticosteroid dependence. One patient received retreatment to an orbit three times, achieving long-term control without corticosteroid dependence. No significant late effects have been observed in retreated patients. Conclusions: Radiotherapy is an effective treatment for acute symptomatic improvement and long-term control of orbital pseudotumor. Orbital retreatment can be of clinical benefit, without apparent increase in morbidity, when initial irradiation fails to achieve complete response.

  4. New Funding Opportunity: High-Efficacy Lamp Product Development

    Broader source: Energy.gov [DOE]

    Submission deadline for letter of intent: May 6, 2016, 5 p.m. ET Submission deadline for full applications: May 23, 2016, 5 p.m. ET The U.S. Department of Energy’s Building Technologies Office Emerging Technologies (ET) program is announcing the availability of up to $3 million in funding to develop energy efficient replacement lamps in general illumination applications.

  5. Materials and Designs for High-Efficacy LED Light Engines

    Broader source: Energy.gov [DOE]

    Lead Performer: Cree, Inc. – Durham, NCDOE Total Funding: $1,499,971Cost Share: $374,993Project Term: 7/1/15 – 6/30/17Funding Opportunity: SSL R&D Funding Opportunity Announcement (FOA) (DE-FOA...

  6. Effects of fluid dynamics on cleaning efficacy of supercritical fluids

    SciTech Connect (OSTI)

    Phelps, M.R.; Willcox, W.A.; Silva, L.J.; Butner, R.S.

    1993-03-01

    Pacific Northwest Laboratory (PNL) and Boeing Aerospace Company are developing a process to clean metal parts using a supercritical solvent. This work is part of an effort to address issues inhibiting the rapid commercialization of Supercritical Fluid Parts Cleaning (SFPC). PNL assembled a SFPC test stand to observe the relationship between the fluid dynamics of the system and the mass transfer of a contaminant from the surface of a contaminated metal coupon into the bulk fluid. The bench-scale test stand consists of a ``Berty`` autoclave modified for these tests and supporting hardware to achieve supercritical fluids parts cleaning. Three separate sets of tests were conducted using supercritical carbon dioxide. For the first two tests, a single stainless steel coupon was cleaned with organic solvents to remove surface residue, doped with a single contaminant, and then cleaned in the SFPC test stand. Contaminants studied were Dow Corning 200 fluid (dimethylpolysiloxane) and Castle/Sybron X-448 High-temperature Oil (a polybutane/mineral oil mixture). A set of 5-minute cleaning runs was conducted for each dopant at various autoclave impeller speeds. Test results from the first two sets of experiments indicate that precision cleaning for difficult-to-remove contaminants can be dramatically improved by introducing and increasing turbulence within the system. Metal coupons that had been previously doped with aircraft oil were used in a third set of tests. The coupons were placed in the SFPC test stand and subjected to different temperatures, pressures, and run times at a constant impeller speed. The cleanliness of each part was measured by Optically Stimulated Electron Emission. The third set of tests show that levels of cleanliness attained with supercritical carbon dioxide compare favorably with solvent and aqueous cleaning levels.

  7. Effects of fluid dynamics on cleaning efficacy of supercritical fluids

    SciTech Connect (OSTI)

    Phelps, M.R.; Willcox, W.A.; Silva, L.J.; Butner, R.S.

    1993-03-01

    Pacific Northwest Laboratory (PNL) and Boeing Aerospace Company are developing a process to clean metal parts using a supercritical solvent. This work is part of an effort to address issues inhibiting the rapid commercialization of Supercritical Fluid Parts Cleaning (SFPC). PNL assembled a SFPC test stand to observe the relationship between the fluid dynamics of the system and the mass transfer of a contaminant from the surface of a contaminated metal coupon into the bulk fluid. The bench-scale test stand consists of a Berty'' autoclave modified for these tests and supporting hardware to achieve supercritical fluids parts cleaning. Three separate sets of tests were conducted using supercritical carbon dioxide. For the first two tests, a single stainless steel coupon was cleaned with organic solvents to remove surface residue, doped with a single contaminant, and then cleaned in the SFPC test stand. Contaminants studied were Dow Corning 200 fluid (dimethylpolysiloxane) and Castle/Sybron X-448 High-temperature Oil (a polybutane/mineral oil mixture). A set of 5-minute cleaning runs was conducted for each dopant at various autoclave impeller speeds. Test results from the first two sets of experiments indicate that precision cleaning for difficult-to-remove contaminants can be dramatically improved by introducing and increasing turbulence within the system. Metal coupons that had been previously doped with aircraft oil were used in a third set of tests. The coupons were placed in the SFPC test stand and subjected to different temperatures, pressures, and run times at a constant impeller speed. The cleanliness of each part was measured by Optically Stimulated Electron Emission. The third set of tests show that levels of cleanliness attained with supercritical carbon dioxide compare favorably with solvent and aqueous cleaning levels.

  8. Evaluation of the efficacy of polyphosphate remediation technology...

    Office of Scientific and Technical Information (OSTI)

    Edge, Ellen Publication Date: 2011-08-31 OSTI Identifier: 1027179 Report Number(s): PNNL-SA-60306 830403000; TRN: US201121%%346 DOE Contract Number: AC05-76RL01830 Resource Type: ...

  9. Very high efficacy electrodeless high intensity discharge lamps

    DOE Patents [OSTI]

    Johnson, P.D.

    1985-10-03

    An electrodeless arc lamp comprises an outer jacket hermetically sealing and thermally protecting an arc tube inside which has an upwardly convex bottom center section. The absence of chemically reactive electrode material makes it possible to use metal halides other than iodides. The tube contains chlorides, bromides or a mixture thereof of scandium and sodium in a nearly equimolar relationship in addition to mercury and an inert gas. Good color balance can be obtained at reduced reservoir temperature and with less power loss. Reduction in wall temperature makes it possible to attain longer lamp life.

  10. The Path to Higher Source, Package, and Product Efficacy

    Energy Savers [EERE]

    * Non-radiative Auger recombination process that limits efficiency at higher current density * Droop limits how hard LEDs can be driven and Lm Luxeon Q Data Sheet 5 Green Gap...

  11. Probable maximum flood (PMF): basic information and problems with the procedure used for its calculation in Russia

    SciTech Connect (OSTI)

    Zhirkevich, A. N.; Asarin, A. E.

    2010-09-15

    A procedure is proposed for enhancement of the hydrologic safety of entities in the tail races of dams.

  12. Comparison of Direct Sequence Spread Spectrum Rake Receiver with a Maximum Ratio Combining Multicarrier Spread Spectrum Receiver

    SciTech Connect (OSTI)

    Daryl Leon Wasden; Hussein Moradi; Behrouz Farhang-Broujeny

    2014-06-01

    This paper presents a theoretical analysis of the performance of a filter bank-based multicarrier spread spectrum (FB-MC-SS) system. We consider an FB-MC-SS setup where each data symbol is spread across multiple subcarriers, but there is no spreading in time. The results are then compared with those of the well-known direct sequence spread spectrum (DS-SS) system with a rake receiver for its best performance. We compare the two systems when the channel noise is white. We prove that as the processing gains of the two systems tend to infinity both approach the same performance. However, numerical simulations show that, in practice, where processing gain is limited, FB-MC-SS outperforms DS-SS.

  13. The Use of Tritiated Wastewater from NPP Cernavoda to Estimate Maximum Soluble Pollutants on Danube-Black Sea Channel

    SciTech Connect (OSTI)

    Varlam, Carmen; Stefanescu, Ioan; Patrascub, Vasile; Varlam, Mihai; Raceanu, Mircea; Enache, Adrian; Bucur, Cristina

    2005-07-15

    In this paper we propose to use tritiated liquid effluents from a CANDU type reactor as a tracer, to study hydrodynamics on Danube-Black Sea Channel. Tritiated water can be used to simulate the transport and dispersion of solutes in mentioned Channel, because it has the same physical characteristic as water. Measured tracer response curves produced from controlled evacuations provide an efficient method of obtaining necessary data. This paper presents the establishing of proper mixing length, and the base line of tritium concentration in studied area. These first steps were used to construct the unit-peak attenuation (UPA) curve for a sector of the Danube-Black Sea Channel.

  14. Max Tech and Beyond: Fluorescent Lamps

    SciTech Connect (OSTI)

    Scholand, Michael

    2012-04-01

    Fluorescent lamps are the most widely used artificial light source today, responsible for approximately 70% of the lumens delivered to our living spaces globally. The technology was originally commercialized in the 1930's, and manufacturers have been steadily improving the efficacy of these lamps over the years through modifications to the phosphors, cathodes, fill-gas, operating frequency, tube diameter and other design attributes. The most efficient commercially available fluorescent lamp is the 25 Watt T5 lamp. This lamp operates at 114-116 lumens per watt while also providing good color rendering and more than 20,000 hours of operating life. Industry experts interviewed indicated that while this lamp is the most efficient in the market today, there is still a further 10 to 14% of potential improvements that may be introduced to the market over the next 2 to 5 years. These improvements include further developments in phosphors, fill-gas, cathode coatings and ultraviolet (UV) reflective glass coatings. The commercialization of these technology improvements will combine to bring about efficacy improvements that will push the technology up to a maximum 125 to 130 lumens per watt. One critical issue raised by researchers that may present a barrier to the realization of these improvements is the fact that technology investment in fluorescent lamps is being reduced in order to prioritize research into light emitting diodes (LEDs) and ceramic metal halide high intensity discharge (HID) lamps. Thus, it is uncertain whether these potential efficacy improvements will be developed, patented and commercialized. The emphasis for premium efficacy will continue to focus on T5 lamps, which are expected to continue to be marketed along with the T8 lamp. Industry experts highlighted the fact that an advantage of the T5 lamp is the fact that it is 40% smaller and yet provides an equivalent lumen output to that of a T8 or T12 lamp. Due to its smaller form factor, the T5 lamp

  15. Buildings Energy Data Book: 7.6 Efficiency Standards for Lighting

    Buildings Energy Data Book [EERE]

    4 Lighting Standards for General Service Incandescent Lamps Prescribed by EISA 2007 General Service Incandescent Effective Date Maximum Wattage Rated Lumen Range Minimum Life Modified Spectrum General Service Incandescent Effective Date Maximum Wattage Rated Lumen Range Minimum Life By 2020, the minimum efficacy for general service incandescent will be 45 lm/W unless the Secretary of Energy has implemented another standard which saves as much or more energy than a 45 lm/W standard. Source(s): U.

  16. The low-pressure sodium lamp

    SciTech Connect (OSTI)

    Hooker, J.D.

    1997-12-31

    For many years before the introduction of the sodium vapor lamp, scientists had been aware of the remarkably high luminous efficacy of the sodium discharge. However, many technical problems had to be overcome before these lamps could be marketed. The first commercial low pressure sodium lamps were introduced in the early 1930s and to this day they remain the most efficient light sources available. The high efficacy is due partly to the fact that these lamps emit nearly monochromatic yellow light, which is very close to the peak sensitivity of the human eye. Sodium lamps have come a long way since their introduction, and efficacies are now approaching 200 lumens per watt. Despite increasing competition from other types of discharge lamp, low pressure sodium lamps of the SOX type find widespread use in road and security lighting, particularly in Great Britain and many other parts of Europe. This paper reviews the operation and development of the low pressure sodium lamp, and shows what makes it different from the many other types of discharge lamp available.

  17. Fluorescent lamp with static magnetic field generating means

    DOE Patents [OSTI]

    Moskowitz, P.E.; Maya, J.

    1987-09-08

    A fluorescent lamp wherein magnetic field generating means (e.g., permanent magnets) are utilized to generate a static magnetic field across the respective electrode structures of the lamp such that maximum field strength is located at the electrode's filament. An increase in efficacy during operation has been observed. 2 figs.

  18. Fluorescent lamp with static magnetic field generating means

    DOE Patents [OSTI]

    Moskowitz, Philip E.; Maya, Jakob

    1987-01-01

    A fluorescent lamp wherein magnetic field generating means (e.g., permanent magnets) are utilized to generate a static magnetic field across the respective electrode structures of the lamp such that maximum field strength is located at the electrode's filament. An increase in efficacy during operation has been observed.

  19. EIS-0012: Petroleum Production at Maximum Efficient Rate, Naval Petroleum Reserve #1, Elk Hills, Kern County, California (also see EA-0261, EA-0334, and EIS-0158-S)

    Broader source: Energy.gov [DOE]

    The U.S. Department of Energy prepared this statement to evaluate the environmental impacts of increasing petroleum production, and of additional or expanded operational facilities, at Elk Hills from 160,000 barrels per day up to 240,000 barrels per day.

  20. Predictions for the top-quark forward-backward asymmetry at high invariant pair mass using the principle of maximum conformality

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Wang, Sheng -Quan; Wu, Xing -Gang; Si, Zong -Guo; Brodsky, Stanley J.

    2016-01-07

    In this study, the D0 collaboration at FermiLab has recently measured the top-quark pair forward-backward asymmetry inmore » $$\\bar{p}p$$ → $$t\\bar{t}$$X reactions as a function of the $$t\\bar{t}$$ invariant mass M$$t\\bar{t}$$. The D0 result for AFB(M$$t\\bar{t}$$ > 650 GeV) is smaller than AFB(M$$t\\bar{t}$$) obtained for small values of M$$t\\bar{t}$$, which may indicate an “increasing-decreasing” behavior for AFB(M$$t\\bar{t}$$ > Mcut). This behavior is not explained using conventional renormalization scale setting, or even by a next-to-next-to-leading order (N2LO) QCD calculation—one predicts a monotonically increasing behavior. In the conventional scale-setting method, one simply guesses a single renormalization scale μr for the argument of the QCD running coupling and then varies it over an arbitrary range. However, the conventional method has inherent difficulties.« less

  1. Summary Notes from 1 November 2007 Generic Technical Issue Discussion on Removal of Highly Radioactive Radionuclides/Key Radionuclides to the Maximum Extent Practical

    Office of Environmental Management (EM)

    Max Total Units *If All Splits, No Rack Units **If Only FW, AC Splits 1000 52 28 28 2000 87 59 35 3000 61 33 15 4000 61 33 15 Totals 261 153 93 ***Costs $1,957,500.00 $1,147,500.00 $697,500.00 Notes: added several refrigerants removed bins from analysis removed R-22 from list 1000lb, no Glycol, CO2 or ammonia Seawater R-404A only * includes seawater units ** no seawater units included *** Costs = (total units) X (estimate of $7500 per unit) 1000lb, air cooled split systems, fresh water Refrig

  2. Experimental study of the maximum resolution and packing density achievable in sintered and non-sintered binder-jet 3D printed steel microchannels

    SciTech Connect (OSTI)

    Elliott, Amy M; Mehdizadeh Momen, Ayyoub; Benedict, Michael; Kiggans Jr, James O

    2015-01-01

    Developing high resolution 3D printed metallic microchannels is a challenge especially when there is an essential need for high packing density of the primary material. While high packing density could be achieved by heating the structure to the sintering temperature, some heat sensitive applications require other strategies to improve the packing density of primary materials. In this study the goal is to develop high green or pack densities microchannels on the scale of 2-300 microns which have a robust mechanical structure. Binder-jet 3D printing is an additive manufacturing process in which droplets of binder are deposited via inkjet into a bed of powder. By repeatedly spreading thin layers of powder and depositing binder into the appropriate 2D profiles, complex 3D objects can be created one layer at time. Microchannels with features on the order of 500 microns were fabricated via binder jetting of steel powder and then sintered and/or infiltrated with a secondary material. The average particle size of the steel powder was varied along with the droplet volume of the inkjet-deposited binder. The resolution of the process, packing density of the primary material, the subsequent features sizes of the microchannels, and the overall microchannel quality were characterized as a function of particle size distribution, droplet sizes and heat treatment temperatures.

  3. Organic solution-processible electroluminescent molecular glasses for non-doped standard red OLEDs with electrically stable chromaticity

    SciTech Connect (OSTI)

    Bi, Xiaoman; Zuo, Weiwei; Liu, Yingliang Zhang, Zhenru; Zeng, Cen; Xu, Shengang; Cao, Shaokui

    2015-10-15

    Highlights: • The D–A–D electroluminescent molecular glasses are synthesized. • Non-doped red electroluminescent film is fabricated by spin-coating. • Red OLED shows stable wavelength, luminous efficiency and chromaticity. • CIE1931 coordinate is in accord with standard red light in PAL system. - Abstract: Organic light-emitting molecular glasses (OEMGs) are synthesized through the introduction of nonplanar donor and branched aliphatic chain into electroluminescent emitters. The target OEMGs are characterized by {sup 1}H NMR, {sup 13}C NMR, IR, UV–vis and fluorescent spectra as well as elemental analysis, TG and DSC. The results indicated that the optical, electrochemical and electroluminescent properties of OEMGs are adjusted successfully by the replacement of electron-donating group. The non-doped OLED device with a standard red electroluminescent emission is achieved by spin-coating the THF solution of OEMG with a triphenylamine moiety. This non-doped red OLED device takes on an electrically stable electroluminescent performance, including the stable maximum electroluminescent wavelength of 640 nm, the stable luminous efficiency of 2.4 cd/A and the stable CIE1931 coordinate of (x, y) = (0.64, 0.35), which is basically in accord with the CIE1931 coordinate (x, y) = (0.64, 0.33) of standard red light in PAL system.

  4. Color stable white phosphorescent organic light emitting diodes with red emissive electron transport layer

    SciTech Connect (OSTI)

    Wook Kim, Jin; Yoo, Seung Il; Sung Kang, Jin; Eun Lee, Song; Kwan Kim, Young; Hwa Yu, Hyeong; Turak, Ayse; Young Kim, Woo

    2015-06-28

    We analyzed the performance of multi-emissive white phosphorescent organic light-emitting diodes (PHOLEDs) in relation to various red emitting sites of hole and electron transport layers (HTL and ETL). The shift of the recombination zone producing stable white emission in PHOLEDs was utilized as luminance was increased with red emission in its electron transport layer. Multi-emissive white PHOLEDs including the red light emitting electron transport layer yielded maximum external quantum efficiency of 17.4% with CIE color coordinates (−0.030, +0.001) shifting only from 1000 to 10 000 cd/m{sup 2}. Additionally, we observed a reduction of energy loss in the white PHOLED via Ir(piq){sub 3} as phosphorescent red dopant in electron transport layer.

  5. Calcium chloride electron injection/extraction layers in organic electronic devices

    SciTech Connect (OSTI)

    Qu, Bo, E-mail: bqu@pku.edu.cn, E-mail: qhgong@pku.edu.cn; Gao, Zhi; Yang, Hongsheng; Xiao, Lixin; Chen, Zhijian; Gong, Qihuang, E-mail: bqu@pku.edu.cn, E-mail: qhgong@pku.edu.cn [State Key Laboratory for Artificial Microstructures and Mesoscopic Physics, Department of Physics, Peking University, Beijing 100871 (China)

    2014-01-27

    Nontoxic calcium chloride (CaCl{sub 2}) was introduced into organic electronic devices as cathode buffer layer (CBL). The turn-on voltage and maximum luminance of organic light-emitting diode (OLED) with 1.5?nm CaCl{sub 2} was 3.5?V and 21960?cd/m{sup 2}, respectively. OLED with 1.5?nm CaCl{sub 2} possessed comparable electroluminescent characteristics to that of the commonly used LiF. Moreover, the performance of the organic photovoltaic device with 0.5?nm CaCl{sub 2} was comparable to that of the control device with LiF. Therefore, CaCl{sub 2} has the potential to be used as the CBL for organic electronic devices.

  6. Biological quality of soils containing hydrocarbons and efficacy of ecological risk reduction by bioremediation alternatives

    SciTech Connect (OSTI)

    Stewart, A.J.; Napolitano, G.E.; Sample, B.E.

    1996-06-01

    This project provides technical support to the Petroleum Environmental Research Forum (PERF; a consortium of petroleum companies) on environmentally acceptable endpoints that may be used to help assess the ecological risk of petroleum hydrocarbon residuals in soils. The project, was designed in consultation with PERF representatives and focuses on the relationship between {open_quotes}chemically available{close_quotes} and {open_quotes}biologically available{close_quotes} measurements of petroleum hydrocarbon compounds in soils, a discrepancy of considerable interest to the petroleum industry. Presently, clean-up standards for soils contaminated with total petroleum hydrocarbon (TPH) constituents are based on concentrations of TPH, as measured in solvent extracts of soil samples. Interestingly, TPH includes a complex mixture of compounds which differ from one another in molecular weight and toxicity. Based on various studies with insecticides, herbicides and metals, some compounds apparently can slowly permeate into soil particles. If this situation occurs, the particle-embedded compounds may be extractable by use of organic solvents, and yet be unavailable biologically. This hypothesis serves as the central focus for our study. If this hypothesis is correct, then soil clean-up standards based on solvent-extractable TPH data may be more stringent than necessary to achieve a desired level of environmental risk. The economic significance of this possibility is considerable, because clean-up costs to achieve a low-risk status would, in most cases, be lower than those needed to achieve a standard based on present limits, which are based on measurements of {open_quotes}extractable{close_quotes} TPH.

  7. EFFICACY OF FILTRATION PROCESSES TO OBTAIN WATER CLARITY AT K EAST SPENT NUCLEAR FUEL (SNF) BASIN

    SciTech Connect (OSTI)

    DUNCAN JB

    2006-09-28

    The objective is to provide water clarity to the K East Basin via filtration processes. Several activities are planned that will challenge not only the capacity of the existing ion exchange modules to perform as needed but also the current filtration system to maintain water clarity. Among the planned activities are containerization of sludge, removal of debris, and hydrolasing the basin walls to remove contamination.

  8. Improved InGaN LED System Efficacy and Cost via Droop Reduction...

    Broader source: Energy.gov (indexed) [DOE]

    Lumileds, LLC - San Jose, CA Partners: Sandia National Laboratories - Albuquerque, NM DOE Total Funding: 1,495,990 Cost Share: 374,000 Project Term: 912015 - 8312017 Funding ...

  9. Saline Infusion Markedly Reduces Impedance and Improves Efficacy of Pulmonary Radiofrequency Ablation

    SciTech Connect (OSTI)

    Gananadha, Sivakumar Morris, David Lawson

    2004-08-15

    Radiofrequency ablation (RFA) is a relatively new technique that has been investigated for the treatment of lung tumors. We evaluated for the first time the in vivo use of saline infusion during radiofrequency ablation of sheep lung. We performed RFA on 5 sheep using open and closed chest RFA and the RITA starburst XL and Xli probes using saline infusion with the Xli probe. The impedance and volume of ablation were compared. A total of 16 ablations were produced, 5 percutaneously and 11 open. The impedance during percutaneous and open RFA without saline infusion was 110 {+-} 16.2 and 183.3 {+-} 105.8 O, respectively. With the saline infusion the impedance was 71.3 {+-} 22O and 103.6 {+-} 37.5O. The effect of this was a significantly larger volume of ablation using the saline infusion during percutaneous RFA (90.6 {+-} 23 cm{sup 3} vs 10.47 {+-} 2.9 cm{sup 3}, p = 0.01) and open RFA (107.8 {+-} 25.8 cm{sup 3} vs 24.9 {+-} 19.3 cm{sup 3}, p = 0.0002). Saline infusion during RFA is associated with lower impedance, higher power delivery and larger lesion size.

  10. Efficacy of fixed filtration for rapid kVp-switching dual energy x-ray systems

    SciTech Connect (OSTI)

    Yao, Yuan; Wang, Adam S.; Pelc, Norbert J.; Department of Radiology, Stanford University, Stanford, California 94305; Department of Electrical Engineering, Stanford University, Stanford, California 94305

    2014-03-15

    Purpose: Dose efficiency of dual kVp imaging can be improved if the two beams are filtered to remove photons in the common part of their spectra, thereby increasing spectral separation. While there are a number of advantages to rapid kVp-switching for dual energy, it may not be feasible to have two different filters for the two spectra. Therefore, the authors are interested in whether a fixed added filter can improve the dose efficiency of kVp-switching dual energy x-ray systems. Methods: The authors hypothesized that a K-edge filter would provide the energy selectivity needed to remove overlap of the spectra and hence increase the precision of material separation at constant dose. Preliminary simulations were done using calcium and water basis materials and 80 and 140 kVp x-ray spectra. Precision of the decomposition was evaluated based on the propagation of the Poisson noise through the decomposition function. Considering availability and cost, the authors chose a commercial Gd{sub 2}O{sub 2}S screen as the filter for their experimental validation. Experiments were conducted on a table-top system using a phantom with various thicknesses of acrylic and copper and 70 and 125 kVp x-ray spectra. The authors kept the phantom exposure roughly constant with and without filtration by adjusting the tube current. The filtered and unfiltered raw data of both low and high energy were decomposed into basis material and the variance of the decomposition for each thickness pair was calculated. To evaluate the filtration performance, the authors measured the ratio of material decomposition variance with and without filtration. Results: Simulation results show that the ideal filter material depends on the object composition and thickness, and ranges across the lanthanide series, with higher atomic number filters being preferred for more attenuating objects. Variance reduction increases with filter thickness, and substantial reductions (40%) can be achieved with a 2 loss in intensity. The authors experimental results validate the simulations, yet were overall slightly worse than expectation. For large objects, conventional (non-K-edge) beam hardening filters perform well. Conclusions: This study demonstrates the potential of fixed K-edge filtration to improve the dose efficiency and material decomposition precision for rapid kVp-switching dual energy systems.

  11. Measuring the efficacy of a root biobarrier with x-ray computed tomography

    SciTech Connect (OSTI)

    Tollner, E.W.; Murphy, C.E. Jr. . Dept. of Agricultural Engineering)

    1990-08-16

    X-ray computed tomography is a useful tool for investigating soil physical properties nondestructively. There is a need to develop proper calibration relationships between soil properties and the x-ray absorption coefficient. The objective of the work was to evaluate soil factors affecting the x-ray absorption coefficient. Based on a theoretical analysis, experimental data from five soils and on results of several other investigators, it was concluded that for many applications, one calibration relationship is applicable to a wide range of soils. The montmorillinitic clay used in the study required special handling due to the extreme shrinkage of this soil upon drying. Knowledge of chemical composition enables approximations but not exact predictions of the x-ray absorption coefficient. The results suggested some reasonable alternative to exhaustive calibration for each anticipated soil condition. Quantification of root activity in terms of root growth and indirectly through water uptake is necessary for understanding plant growth dynamics. X-ray computed tomography (CT) enables qualitative as well as two quantitative outputs, one of which can lead to conclusions regarding root activity. A greenhouse study involving soil columns (Lakeland sand, bulk density 1.4 Mg/m{sup 3}) planted to soybean, Bahiagras, and control (no vegetation) was conducted in 1989. A treflan based on chemical barrier was placed in half of the soil column of each species. The mean x-ray absorption correlated to water content. Results suggested that root presence can also be indirectly inferred based on water content drawn down during planned stress events. It was concluded that x-ray CT may have a niche in soil-water-plant relation studies, particularly when plant species have large roots. 35 refs., 13 figs., 8 tabs.

  12. Notes on the efficacy of wet versus dry screening of fly ash

    SciTech Connect (OSTI)

    Valentim, B.; Hower, J.C.; Flores, D.; Guedes, A.

    2008-08-15

    The methodology used to obtain fly ash subsamples of different sizes is generally based on wet or dry sieving methods. However, the worth of such methods is not certain if the methodology applied is not mentioned in the analytical procedure. After performing a fly ash mechanical dry, sieving, the authors compared those results with the ones obtained by laser diffraction on the same samples and found unacceptable discrepancies. A preliminary, study of a wet sieving analysis carried out on an economizer fly ash sample showed that this method was more effective than the dry sieving. The importance of standardizing the way samples are handled, pretreated and presented to the instrument of analysis are suggested and interlaboratory reproducibility trials are needed to create a common standard methodology to obtain large amounts of fly ash size fraction subsamples.

  13. Evaluating the Efficacy of Wavelet Configurations on Turbulent-Flow Data

    SciTech Connect (OSTI)

    Li, Shaomeng; Gruchalla, Kenny; Potter, Kristin; Clyne, John; Childs, Hank

    2015-10-25

    I/O is increasingly becoming a significant constraint for simulation codes and visualization tools on modern supercomputers. Data compression is an attractive workaround, and, in particular, wavelets provide a promising solution. However, wavelets can be applied in multiple configurations, and the variations in configuration impact accuracy, storage cost, and execution time. While the variation in these factors over wavelet configurations have been explored in image processing, they are not well understood for visualization and analysis of scientific data. To illuminate this issue, we evaluate multiple wavelet configurations on turbulent-flow data. Our approach is to repeat established analysis routines on uncompressed and lossy-compressed versions of a data set, and then quantitatively compare their outcomes. Our findings show that accuracy varies greatly based on wavelet configuration, while storage cost and execution time vary less. Overall, our study provides new insights for simulation analysts and visualization experts, who need to make tradeoffs between accuracy, storage cost, and execution time.

  14. Efficacy of a Solution-Based Approach for Making Sodalite Waste...

    Office of Scientific and Technical Information (OSTI)

    This paper describes various approaches for making sodalite with a LiCl-Li2O oxide reduction salt used to recover uranium from used oxide fuel. The approaches include sol-gel and ...

  15. On the efficacy of imploding plasma liners for magnetized fusion target compression

    SciTech Connect (OSTI)

    Parks, P. B.

    2008-06-15

    A new theoretical model is formulated to study the idea of merging a spherical array of converging plasma jets to form a 'plasma liner' that further converges to compress a magnetized plasma target to fusion conditions [Y. C. F. Thio et al., 'Magnetized target fusion in a spheroidal geometry with standoff drivers', Current Trends in International Fusion Research II, edited by E. Panarella (National Research Council Canada, Ottawa, Canada, 1999)]. For a spherically imploding plasma liner shell with high initial Mach number (M=liner speed/sound speed) the rise in liner density with decreasing radius r goes as {rho}{approx}1/r{sup 2}, for any constant adiabatic index {gamma}=d ln p/d ln {rho}. Accordingly, spherical convergence amplifies the ram pressure of the liner on target by the factor A{approx}C{sup 2}, indicating strong coupling to its radial convergence C=r{sub m}/R, where r{sub m}(R)=jet merging radius (compressed target radius), and A=compressed target pressure/initial liner ram pressure. Deuterium-tritium (DT) plasma liners with initial velocity {approx}100 km/s and {gamma}=5/3, need to be hypersonic M{approx}60 and thus cold in order to realize values of A{approx}10{sup 4} necessary for target ignition. For optically thick DT liners, T<2 eV, n>10{sup 19}-10{sup 20} cm{sup -3}, blackbody radiative cooling is appreciable and may counteract compressional heating during the later stages of the implosion. The fluid then behaves as if the adiabatic index were depressed below 5/3, which in turn means that the same amplification A=1.6x10{sup 4} can be accomplished with a reduced initial Mach number M{approx_equal}12.7({gamma}-0.3){sup 4.86}, valid in the range (10

  16. Simulation to assess the efficacy of US airport entry scrreening of passengers for pandemic influenza

    SciTech Connect (OSTI)

    Mcmahon, Benjamin

    2009-01-01

    We present our methodology and stochastic discrete-event simulation developed to model the screening of passengers for pandemic influenza at the US port-of-entry airports. Our model uniquely combines epidemiology modelling, evolving infected states and conditions of passengers over time, and operational considerations of screening in a single simulation. The simulation begins with international aircraft arrivals to the US. Passengers are then randomly assigned to one of three states -- not infected, infected with pandemic influenza and infected with other respiratory illness. Passengers then pass through various screening layers (i.e. pre-departure screening, en route screening, primary screening and secondary screening) and ultimately exit the system. We track the status of each passenger over time, with a special emphasis on false negatives (i.e. passengers infected with pandemic influenza, but are not identified as such) as these passengers pose a significant threat as they could unknowingly spread the pandemic influenza virus throughout our nation.

  17. Efficacy of backfilling and other engineered barriers in a radioactive waste repository in salt

    SciTech Connect (OSTI)

    Claiborne, H.C.

    1982-09-01

    In the United States, investigation of potential host geologic formations was expanded in 1975 to include hard rocks. Potential groundwater intrusion is leading to very conservative and expensive waste package designs. Recent studies have concluded that incentives for engineered barriers and 1000-year canisters probably do not exist for reasonable breach scenarios. The assumption that multibarriers will significantly increase the safety margin is also questioned. Use of a bentonite backfill for surrounding a canister of exotic materials was developed in Sweden and is being considered in the US. The expectation that bentonite will remain essentially unchanged for hundreds of years for US repository designs may be unrealistic. In addition, thick bentonite backfills will increase the canister surface temperature and add much more water around the canister. The use of desiccant materials, such as CaO or MgO, for backfilling seems to be a better method of protecting the canister. An argument can also be made for not using backfill material in salt repositories since the 30-cm-thick space will provide for hole closure for many years and will promote heat transfer via natural convection. It is concluded that expensive safety systems are being considered for repository designs that do not necessarily increase the safety margin. It is recommended that the safety systems for waste repositories in different geologic media be addressed individually and that cost-benefit analyses be performed.

  18. DOE Publishes Pricing and Efficacy Trend Analysis for Utility Program Planning

    Office of Energy Efficiency and Renewable Energy (EERE)

    DOE has published a report to help utilities and energy efficiency organizations forecast the order in which important SSL applications will become cost-effective and estimate when each tipping point will be reached. It includes performance

  19. The Efficacy of Radiation Therapy in the Treatment of Graves' Orbitopathy

    SciTech Connect (OSTI)

    Matthiesen, Chance; Thompson, J. Spencer; Thompson, David; Farris, Bradley; Wilkes, Byron; Ahmad, Salahuddin; Herman, Terence; Bogardus, Carl

    2012-01-01

    Purpose: To review our institutional outcomes of patients treated with radiation therapy (RT) for Graves' orbitopathy (GO), assess the role of orbital reirradiation, and identify prognostic factors of complete response (CR). Methods and Materials: This is a retrospective review of 211 patients who presented with a diagnosis of GO and received RT between January 2000-2010. RT dose was 20 Gy in 10 fractions. Patient median age was 51 years (range, 15-84 years), median follow-up was 11 months (range, 1-88 months). Patient symptoms included any combination of proptosis (90.9%), extraocular muscle dysfunction (78.9%), soft tissue signs (68.4%), and diplopia (58.4%). Corticosteroids were used as first-line therapy in 20.6% of patients. Among those who achieved either CR or partial response (PR), prognostic factors were evaluated. Results: Stabilization of disease without recurrence was clinically achieved overall in 202 patients (96.7%). At the completion of RT, 176 patients (84.2%) reported a symptomatic improvement of pretreatment symptoms. CR of GO symptoms was achieved using multiple treatment modalities, including RT by 93 patients (44.5%), of which 32 patients received RT only. Corticosteroids were discontinued in 97.8% of patients who received them as initial therapy. Surgical intervention following radiotherapy was required for 144 (68.9%) of all patients. Fourteen patients received orbital reirradiation for persistent or recurrent symptoms. Five of these achieved a CR, and the other nine achieved disease stabilization but retained persistent ocular symptoms. Long-term side effects of RT included dry eyes (12%). Of the prognostic factors we investigated, only gender predicted CR, which was less common in men (33.9%) than in women (49.7%) p = 0.0471. Conclusions: Orbital radiation for GO is an established treatment modality for patients. Orbital reirradiation is beneficial for patients who do not respond to initial RT or experience symptom recurrence without an apparent risk of increased morbidity.

  20. Improved InGaN LED System Efficacy and Cost via Droop Reduction

    Broader source: Energy.gov [DOE]

    Lead Performer: Lumileds, LLC – San Jose, CAPartners: Sandia National Laboratories – Albuquerque, NMDOE Total Funding: $1,495,990Cost Share: $374,000Project Term: 9/1/2015 - 8/31/2017Funding...

  1. Optical and ultraviolet observations of the narrow-lined type Ia SN 2012fr in NGC 1365

    SciTech Connect (OSTI)

    Zhang, Ju-Jia; Bai, Jin-Ming; Wang, Bo; Liu, Zheng-Wei [Yunnan Observatories (YNAO), Chinese Academy of Sciences, Kunming 650011 (China); Wang, Xiao-Feng; Zhao, Xu-Lin; Chen, Jun-Cheng [Physics Department and Tsinghua Center for Astrophysics (THCA), Tsinghua University, Beijing 100084 (China); Zhang, Tian-Meng, E-mail: jujia@ynao.ac.cn, E-mail: baijinming@ynao.ac.cn, E-mail: wang_xf@mail.tsinghua.edu.cn [National Astronomical Observatories of China (NAOC), Chinese Academy of Sciences, Beijing 100012 (China)

    2014-07-01

    Extensive optical and ultraviolet (UV) observations of the type Ia supernova (SN Ia) 2012fr are presented in this paper. It has a relatively high luminosity, with an absolute B-band peak magnitude of about 19.5 mag and a smaller post-maximum decline rate than normal SNe Ia (e.g., ?m {sub 15}(B) =0.85 0.05 mag). Based on the UV and optical light curves, we derived that a {sup 56}Ni mass of about 0.88 M {sub ?} was synthesized in the explosion. The earlier spectra are characterized by noticeable high-velocity features of Si II ?6355 and Ca II with velocities in the range of ?22, 000-25, 000 km s{sup 1}. At around the maximum light, these spectral features are dominated by the photospheric components which are noticeably narrower than normal SNe Ia. The post-maximum velocity of the photosphere remains almost constant at ?12,000 km s{sup 1} for about one month, reminiscent of the behavior of some luminous SNe Ia like SN 1991T. We propose that SN 2012fr may represent a subset of the SN 1991T-like SNe Ia viewed in a direction with a clumpy or shell-like structure of ejecta, in terms of a significant level of polarization reported in Maund et al. in 2013.

  2. High Efficiency, Illumination Quality OLEDs for Lighting

    SciTech Connect (OSTI)

    Joseph Shiang; James Cella; Kelly Chichak; Anil Duggal; Kevin Janora; Chris Heller; Gautam Parthasarathy; Jeffery Youmans; Joseph Shiang

    2008-03-31

    emission spectrum could be adjusted to maximize performance for lighting (e.g. blackbody temperature, color rendering and luminous efficacy) while keeping the properties of the underlying blue OLED constant. The success of the downconversion approach is ultimately based upon the ability to produce efficient emission in the blue. Table 1 presents a comparison of the current performance of the conjugated polymer, dye-doped polymer, and dendrimer approaches to making a solution-processed blue OLED as 2006. Also given is the published state of the art performance of a vapor-deposited blue OLED. One can see that all the approaches to a blue OLED give approximately the same external quantum efficiency at 500 cd/m{sup 2}. However, due to its low operating voltage, the fluorescent conjugated polymer approach yields a superior power efficiency at the same brightness.

  3. WE-D-9A-06: Open Source Monitor Calibration and Quality Control Software for Enterprise Display Management

    SciTech Connect (OSTI)

    Bevins, N; Vanderhoek, M; Lang, S; Flynn, M

    2014-06-15

    Purpose: Medical display monitor calibration and quality control present challenges to medical physicists. The purpose of this work is to demonstrate and share experiences with an open source package that allows for both initial monitor setup and routine performance evaluation. Methods: A software package, pacsDisplay, has been developed over the last decade to aid in the calibration of all monitors within the radiology group in our health system. The software is used to calibrate monitors to follow the DICOM Grayscale Standard Display Function (GSDF) via lookup tables installed on the workstation. Additional functionality facilitates periodic evaluations of both primary and secondary medical monitors to ensure satisfactory performance. This software is installed on all radiology workstations, and can also be run as a stand-alone tool from a USB disk. Recently, a database has been developed to store and centralize the monitor performance data and to provide long-term trends for compliance with internal standards and various accrediting organizations. Results: Implementation and utilization of pacsDisplay has resulted in improved monitor performance across the health system. Monitor testing is now performed at regular intervals and the software is being used across multiple imaging modalities. Monitor performance characteristics such as maximum and minimum luminance, ambient luminance and illuminance, color tracking, and GSDF conformity are loaded into a centralized database for system performance comparisons. Compliance reports for organizations such as MQSA, ACR, and TJC are generated automatically and stored in the same database. Conclusion: An open source software solution has simplified and improved the standardization of displays within our health system. This work serves as an example method for calibrating and testing monitors within an enterprise health system.

  4. Full phosphorescent white-light organic light-emitting diodes with improved color stability and efficiency by fine tuning primary emission contributions

    SciTech Connect (OSTI)

    Hua, Wang, E-mail: wmsu2008@sinano.ac.cn, E-mail: wanghua001@tyut.edu.cn; Du, Xiaogang [Key Laboratory of Interface Science and Engineering in Advanced Materials, Taiyuan University of Technology, Ministry of Education, Taiyuan 030024 (China) [Key Laboratory of Interface Science and Engineering in Advanced Materials, Taiyuan University of Technology, Ministry of Education, Taiyuan 030024 (China); Research Center of Advanced Materials Science and Technology, Taiyuan University of Technology, Taiyuan 030024 (China); Su, Wenming, E-mail: wmsu2008@sinano.ac.cn, E-mail: wanghua001@tyut.edu.cn; Zhang, Dongyu [Printable Electronics Research Centre, Suzhou Institute of Nano-Tech and Nano-Bionics, CAS, suzhou 215123 (China)] [Printable Electronics Research Centre, Suzhou Institute of Nano-Tech and Nano-Bionics, CAS, suzhou 215123 (China); Lin, Wenjing [Key Laboratory of Interface Science and Engineering in Advanced Materials, Taiyuan University of Technology, Ministry of Education, Taiyuan 030024 (China) [Key Laboratory of Interface Science and Engineering in Advanced Materials, Taiyuan University of Technology, Ministry of Education, Taiyuan 030024 (China); Research Center of Advanced Materials Science and Technology, Taiyuan University of Technology, Taiyuan 030024 (China); Printable Electronics Research Centre, Suzhou Institute of Nano-Tech and Nano-Bionics, CAS, suzhou 215123 (China)

    2014-02-15

    In this paper, a novel type of white-light organic light emitting diode (OLED) with high color stability was reported, in which the yellow-light emission layer of (4,4{sup ?}-N,N{sup ?}-dicarbazole)biphenyl (CBP) : tris(2-phenylquinoline-C2,N{sup ?})iridium(III) (Ir(2-phq){sub 3}) was sandwiched by double blue-light emission layers of 1,1-bis-[(di-4-tolylamino)pheny1]cyclohexane (TAPC) : bis[4,6-(di-fluorophenyl)-pyridinato-N,C2{sup ?}]picolinate (FIrpic) and tris[3-(3-pyridyl)mesityl]borane (3TPYMB):FIrpic. And, it exhibited the maximum current efficiency of 33.1 cd/A, the turn-on voltage at about 3 V and the maximum luminance in excess of 20000 cd/m{sup 2}. More important, it realized very stable white-light emission, and its CIE(x, y) coordinates only shift from (0.34, 0.37) to (0.33, 0.37) as applied voltage increased from 5 V to 12 V. It is believed that the new scheme in emission layer of white-light OLED can fine tune the contribution of primary emission with applied voltage changed, resulting in high quality white-light OLED.

  5. Energy Efficiency of LEDs

    Broader source: Energy.gov [DOE]

    This fact sheet discusses the current state of the LED market and discusses package efficacy, luminaire efficacy, and application efficacy.

  6. The depletion of Interleukin-8 causes cell cycle arrest and increases the efficacy of docetaxel in breast cancer cells

    SciTech Connect (OSTI)

    Shao, Nan; Chen, Liu-Hua; Ye, Run-Yi; Lin, Ying; Wang, Shen-Ming

    2013-02-15

    Highlights: ? IL-8 depletion affects cell cycle distribution. ? Intrinsic IL-8 mediates breast cancer cell migration and invasion. ? IL-8 siRNA down regulates key factors that control survival and metastatic pathway. ? IL-8 depletion reduces integrin ?3 expression. ? IL-8 depletion increases the chemosensitivity to docetaxel. -- Abstract: IL-8 is a multi-functional pro-inflammatory chemokine, which is highly expressed in cancers, such as ER-negative breast cancer. The present study demonstrates the pervasive role of IL-8 in the malignant progression of ER-negative breast cancer. IL-8 siRNA inhibited proliferation and delayed the G1 to S cell cycle progression in MDA-MB-231 and BT549 cells. IL-8 silencing resulted in the upregulation of the CDK inhibitor p27, the downregulation of cyclin D1, and the reduction of phosphorylated-Akt and NF-?B activities. IL-8 depletion also increased the chemosensitivity to docetaxel. These results indicate a role for IL-8 in promoting tumor cell survival and resistance to docetaxel and highlight the potential therapeutic significance of IL-8 depletion in ER-negative breast cancer patients.

  7. Efficacy and Toxicity of Chemoradiotherapy Using Intensity-Modulated Radiotherapy for Unknown Primary of Head and Neck

    SciTech Connect (OSTI)

    Sher, David J.; Balboni, Tracy A.; Haddad, Robert I.; Norris, Charles M.; Posner, Marshall R.; Wirth, Lori J.; Goguen, Laura A.; Annino, Donald; Tishler, Roy B.

    2011-08-01

    Purpose: No single standard treatment paradigm is available for head-and-neck squamous cell carcinoma of an unknown primary (HNCUP). Bilateral neck radiotherapy with mucosal axis irradiation is widely used, with or without chemotherapy and/or surgical resection. Intensity-modulated radiotherapy (IMRT) is a highly conformal method for delivering radiation that is becoming the standard of care and might reduce the long-term treatment-related sequelae. We report the Dana-Farber Cancer Institute experience with IMRT-based treatment for HNCUP. Patients and Materials: A retrospective study of all patients treated at the Dana-Farber Cancer Institute for HNCUP with IMRT between August 2004 and January 2009. The primary endpoint was overall survival; the secondary endpoints were locoregional and distant control, and acute and chronic toxicity. Results: A total of 24 patients with HNCUP were included. Of these patients, 22 had Stage N2 disease or greater. All patients underwent neck computed tomography, positron emission tomography-computed tomography, and examination under anesthesia with directed biopsies. Of the 24 patients, 22 received concurrent chemotherapy, and 7 (29%) also underwent induction chemotherapy. The median involved nodal dose was 70 Gy, and the median mucosal dose was 60 Gy. With a median follow-up of 2.1 years, the 2-year actuarial overall survival and locoregional control rate was 92% and 100%, respectively. Only 25% of the patients had Grade 2 xerostomia, although 11 patients (46%) required esophageal dilation for stricture. Conclusion: In a single-institution series, IMRT-based chemoradiotherapy for HNCUP was associated with superb overall survival and locoregional control. The xerostomia rates were promising, but the aggressive therapy was associated with significant rates of esophageal stenosis.

  8. Efficacy of Single-Suture Incision Closures in Tagged Juvenile Chinook Salmon Exposed to Simulated Turbine Passage

    SciTech Connect (OSTI)

    Boyd, James W.; Deters, Katherine A.; Brown, Richard S.; Eppard, M. B.

    2011-09-01

    Reductions in the size of acoustic transmitters implanted in migrating juvenile salmonids have resulted in the use of a shorter incision-one that may warrant only a single suture for closure. However, it is not known whether a single suture will sufficiently hold the incision closed when fish are decompressed and when outward pressure is placed on the surgical site during turbine passage through hydroelectric dams. The objective of this study was to evaluate the effectiveness of single-suture incision closures on five response variables in juvenile Chinook salmon Oncorhynchus tshawytscha that were subjected to simulated turbine passage. An acoustic transmitter (0.43 g in air) and a passive integrated transponder tag (0.10 g in air) were implanted in each fish; the 6-mm incisions were closed with either one suture or two sutures. After exposure to simulated turbine passage, none of the fish exhibited expulsion of transmitters. In addition, the percentage of fish with suture tearing, incision tearing, or mortal injury did not differ between treatments. Expulsion of viscera through the incision was higher among fish that received one suture (12%) than among fish that received two sutures (1%). The higher incidence of visceral expulsion through single-suture incisions warrants concern. Consequently, for cases in which tagged juvenile salmonidsmay be exposed to turbine passage, we do not recommend the use of one suture to close 6-mm incisions associated with acoustic transmitter implantation.

  9. Assessment of the efficacy of laser hyperthermia and nanoparticle-enhanced therapies by heat shock protein analysis

    SciTech Connect (OSTI)

    Tang, Fei; Zhang, Ye; Zhang, Juan; Liu, Ran; Guo, Junwei

    2014-03-15

    Tumor thermotherapy is a method of cancer treatment wherein cancer cells are killed by exposing the body tissues to high temperatures. Successful clinical implementation of this method requires a clear understanding and assessment of the changes of the tumor area after the therapy. In this study, we evaluated the effect of near-infrared laser tumor thermotherapy at the molecular, cellular, and physical levels. We used single-walled carbon nanotubes (SWNTs) in combination with this thermotherapy. We established a mouse model for breast cancer and randomly divided the mice into four groups: mice with SWNT-assisted thermotherapy; mice heat treated without SWNT; mice injected with SWNTs without thermotherapy; and a control group. Tumors were irradiated using a near-infrared laser with their surface temperature remaining at approximately 45 C. We monitored the tumor body growth trend closely by daily physical measurements, immunohistochemical staining, and H and E (hematoxylin-eosin) staining by stage. Our results showed that infrared laser hyperthermia had a significant inhibitory effect on the transplanted breast tumor, with an inhibition rate of 53.09%, and also significantly reduced the expression of the heat shock protein Hsp70. Furthermore, we have found that protein analysis and histological analysis can be used to assess therapeutic effects effectively, presenting broad application prospects for determining the effect of different treatments on tumors. Finally, we discuss the effects of SWNT-assisted near-infrared laser tumor thermotherapy on tumor growth at the molecular, cellular, and physical levels.

  10. Oil-spill cleanup agent efficacy, toxicity, and biodegradation: An annotated bibliography, 1984-1991. Final report

    SciTech Connect (OSTI)

    Tjeerdema, R.S.; Smalheer, D.L.; Jacobson, S.

    1992-03-01

    The annotated bibliography presents literature published between 1984 and 1991 on the environmental fate of petroleum and on all aspects of petroleum and cleanup agent toxicology, including toxicity, effectiveness, biodegradation and analytical methodology. Abstracts and a subject index are provided to facilitate specific searches. The project was supported by the California Department of Fish and Game, Office of Oil Spill Prevention and Response.

  11. Role of curative radiotherapy in the treatment of lung cancer. [Clinical factors effecting efficacy and incidence of complications

    SciTech Connect (OSTI)

    Coy, P.; Kennelly, G.M.

    1980-02-15

    From 1963 to 1974, 141 patients with lung cancer were treated with curative intent in the A. Maxwell Evans Clinic in Vancouver. The clinical presentation, age and sex distribution, histology, and reasons for surgery not being carried out are examined. The results of this treatment are presented. An attempt has been made to isolate a group of patients who have a better prognosis so that treatment selection can be improved. Hemoptysis, cough, dyspnea, and incidental finding on routine chest x-ray were the most common manner of presentation. Thirty-four percent of the patients were over 70 years of age and 13% were women. The crude overall three- and five-year survival rates were 18 and 10% (19 and 9% in the men, 17 and 14% in the women). Patients presenting with dyspnea had a better survival than those presenting with cough and hemoptysis. Patients with lesions less than 3 cm in diameter had a 28% three-year survival, compared with 14% for lesions greater than 5 cm in diameter. The three- and five-year survival rates in patients over 70 years of age were 23 and 17% respectively. The response to treatment and the survival were better in the patients with squamous cell carcinoma. Twenty-two percent were alive at three years and 12% at five years as compared with 9 and 5% for other histologies. Fifty-four percent of the 35 patients with a complete response and with squamous cell carcinoma were alive at three years, compared with only 8% of the 12 patients with other histologies who showed a complete response.

  12. The efficacy of post porosity plasma protection against vacuum-ultraviolet damage in porous low-k materials

    SciTech Connect (OSTI)

    Lionti, K.; Volksen, W.; Darnon, M.; Magbitang, T.; Dubois, G.

    2015-03-21

    As of today, plasma damage remains as one of the main challenges to the reliable integration of porous low-k materials into microelectronic devices at the most aggressive node. One promising strategy to limit damage of porous low-k materials during plasma processing is an approach we refer to as post porosity plasma protection (P4). In this approach, the pores of the low-k material are filled with a sacrificial agent prior to any plasma treatment, greatly minimizing the total damage by limiting the physical interactions between plasma species and the low-k material. Interestingly, the contribution of the individual plasma species to the total plasma damage is not fully understood. In this study, we investigated the specific damaging effect of vacuum-ultraviolet (v-UV) photons on a highly porous, k = 2.0 low-k material and we assessed the P4 protective effect against them. It was found that the impact of the v-UV radiation varied depending upon the v-UV emission lines of the plasma. More importantly, we successfully demonstrated that the P4 process provides excellent protection against v-UV damage.

  13. Development and Demonstration of a Modeling Framework for Assessing the Efficacy of Using Mine Water for Thermoelectric Power Generation

    SciTech Connect (OSTI)

    2010-03-01

    Thermoelectric power plants use large volumes of water for condenser cooling and other plant operations. Traditionally, this water has been withdrawn from the cleanest water available in streams and rivers. However, as demand for electrical power increases it places increasing demands on freshwater resources resulting in conflicts with other off stream water users. In July 2002, NETL and the Governor of Pennsylvania called for the use of water from abandoned mines to replace our reliance on the diminishing and sometimes over allocated surface water resource. In previous studies the National Mine Land Reclamation Center (NMLRC) at West Virginia University has demonstrated that mine water has the potential to reduce the capital cost of acquiring cooling water while at the same time improving the efficiency of the cooling process due to the constant water temperatures associated with deep mine discharges. The objectives of this project were to develop and demonstrate a user-friendly computer based design aid for assessing the costs, technical and regulatory aspects and potential environmental benefits for using mine water for thermoelectric generation. The framework provides a systematic process for evaluating the hydrologic, chemical, engineering and environmental factors to be considered in using mine water as an alternative to traditional freshwater supply. A field investigation and case study was conducted for the proposed 300 MW Beech Hollow Power Plant located in Champion, Pennsylvania. The field study based on previous research conducted by NMLRC identified mine water sources sufficient to reliably supply the 2-3,000gpm water supply requirement of Beech Hollow. A water collection, transportation and treatment system was designed around this facility. Using this case study a computer based design aid applicable to large industrial water users was developed utilizing water collection and handling principals derived in the field investigation and during previous studies of mine water and power plant cooling. Visual basic software was used to create general information/evaluation modules for a range of power plant water needs that were tested/verified against the Beech Hollow project. The program allows for consideration of blending mine water as needed as well as considering potential thermal and environmental benefits that can be derived from using constant temperature mine water. Users input mine water flow, quality, distance to source, elevations to determine collection, transport and treatment system design criteria. The program also evaluates low flow volumes and sustainable yields for various sources. All modules have been integrated into a seamless user friendly computer design aid and user's manual for evaluating the capital and operating costs of mine water use. The framework will facilitate the use of mine water for thermoelectric generation, reduce demand on freshwater resources and result in environmental benefits from reduced emissions and abated mine discharges.

  14. On the efficacy of stochastic collocation, stochastic Galerkin, and stochastic reduced order models for solving stochastic problems

    SciTech Connect (OSTI)

    Richard V. Field, Jr.; Emery, John M.; Grigoriu, Mircea Dan

    2015-05-19

    The stochastic collocation (SC) and stochastic Galerkin (SG) methods are two well-established and successful approaches for solving general stochastic problems. A recently developed method based on stochastic reduced order models (SROMs) can also be used. Herein we provide a comparison of the three methods for some numerical examples; our evaluation only holds for the examples considered in the paper. The purpose of the comparisons is not to criticize the SC or SG methods, which have proven very useful for a broad range of applications, nor is it to provide overall ratings of these methods as compared to the SROM method. Furthermore, our objectives are to present the SROM method as an alternative approach to solving stochastic problems and provide information on the computational effort required by the implementation of each method, while simultaneously assessing their performance for a collection of specific problems.

  15. A Preclinical Study of the Safety and Efficacy of Occlusin Trade-Mark-Sign 500 Artificial Embolization Device in Sheep

    SciTech Connect (OSTI)

    Owen, Richard J.; Nation, Patrick N.; Polakowski, Robert; Biliske, Jennifer A.; Tiege, Paul B.

    2012-06-15

    Introduction: This study evaluated the safety, effectiveness, and biodegradation of a new embolic agent, Occlusin Trade-Mark-Sign 503 Artificial Embolization Device (OCL 503). The agent consists of biodegradable poly-lactic-co-glycolic acid microspheres (150-212 {mu}m) coated with type I bovine collagen and was compared with Embosphere{sup Registered-Sign} Microspheres (300-500 {mu}m) in this controlled study of uterine artery embolization (UAE) in sheep. Methods: Unilateral UAE was performed in 32 adult ewes randomly assigned. Vessels were embolized to effective stasis. The cohort was divided into four groups, which were sacrificed at 1, 3, 6, and 12 months. Results: Both agents were 100% effective in achieving stasis. At 6 months, all OCL 503-treated arteries were occluded, the microspheres degraded with time, and at 12 months all four animals examined demonstrated recanalization. OCL 503 was found in the untreated uterine artery in one animal with no other evidence of non target embolization. In the Embosphere-treated group, all vessels remained occluded and microspheres were detected in the contralateral uterine artery in 6 of 15 examined vessels and in 10 vaginal, 2 ovarian, and 1 vesical artery. No procedural-related complications were seen in either group. Conclusions: OCL 503 is as effective an embolic agent as Embosphere{sup Registered-Sign} Microspheres when embolizing ovine uterine arteries and resorbs with time, allowing recanalization of the treated arteries. No device-related issues or adverse events were observed.

  16. On the efficacy of stochastic collocation, stochastic Galerkin, and stochastic reduced order models for solving stochastic problems

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Richard V. Field, Jr.; Emery, John M.; Grigoriu, Mircea Dan

    2015-05-19

    The stochastic collocation (SC) and stochastic Galerkin (SG) methods are two well-established and successful approaches for solving general stochastic problems. A recently developed method based on stochastic reduced order models (SROMs) can also be used. Herein we provide a comparison of the three methods for some numerical examples; our evaluation only holds for the examples considered in the paper. The purpose of the comparisons is not to criticize the SC or SG methods, which have proven very useful for a broad range of applications, nor is it to provide overall ratings of these methods as compared to the SROM method.more » Furthermore, our objectives are to present the SROM method as an alternative approach to solving stochastic problems and provide information on the computational effort required by the implementation of each method, while simultaneously assessing their performance for a collection of specific problems.« less

  17. Analysis of transient electron energy in a micro dielectric barrier discharge for a high performance plasma display panel

    SciTech Connect (OSTI)

    Uchida, Giichiro; Kajiyama, Hiroshi; Shinoda, Tsutae; Uchida, Satoshi

    2010-01-15

    We present here analysis of electron energy of a micro dielectric barrier discharge (micro-DBD) for alternating-current plasma display panel (ac-PDP) with Ne/Xe gas mixture by using the optical emission spectroscopy (OES). The OES method is quite useful to evaluate a variety of electron energy in a high pressure DBD ignited in a PDP small cell. Experiment shows that the ratio of Ne emission intensity (I{sub Ne}) relative to Xe emission intensity (I{sub Xe}) drastically decreases with time. This temporal profile is well consistent with dynamic behavior of electron temperature in a micro-DBD, calculated in one-dimensional fluid model. I{sub Ne}/I{sub Xe} also decreases with an increase in Xe gas pressure and a decrease in applied voltage especially in the initial stage of discharge, and these reflect the basic features of electron temperature in a micro-DBD. The influences of plasma parameters such as electron temperature on luminous efficacy are also theoretically analyzed using one-dimensional fluid model. The low electron temperature, which is attained at high Xe gas pressure, realizes the efficient Xe excitation for vacuum ultraviolet radiation. The high Xe-pressure condition also induces the rapid growth of discharge and consequent high plasma density, resulting in high electron heating efficiency.

  18. Demonstration of LED Street Lighting in Kansas City, MO

    SciTech Connect (OSTI)

    Kinzey, Bruce R.; Royer, Michael P.; Hadjian, M.; Kauffman, Rick

    2013-06-10

    Nine different streetlighting products were installed on various streets in Kansas City, Missouri during February, 2011, to evaluate their performance relative to the incumbent high-pressure sodium (HPS) lighting. The applications investigated included 100 W, 150 W, 250 W, and 400 W HPS installations. Initial measurements and comparisons included power, illuminance, and luminance; sample illuminance readings have continued at each of the nine locations at roughly 1,000-hour operating intervals since then. All of the LED products consumed less power than their HPS counterparts—with a mean difference of 39% and a range of 31% to 51%—but they also emitted 31% fewer lumens, on average. The net result is just a 15% increase in mean efficacy. Applying the city’s stringent light loss factors to the initial measured data meant that five of the LED products (and two of the HPS luminaires) were predicted to eventually fail to meet the specified mean illuminance over their lifetimes; however, the specified light loss levels are not expected to be reached by the LED products until some distant future date (between 12 and 30 years after installation according to manufacturer specification sheet estimates). The practical value of designing streetlighting systems to meet illumination requirements more than 15 years in the future is questioned. Numerous sources of variation in field measurements are noted throughout the report, particularly seasonal influences such as ambient temperature and foliage that are evident in the time-series illuminance data.

  19. CALiPER Application Summary Report 21. Linear (T8) LED Lamps

    SciTech Connect (OSTI)

    2014-03-01

    This report focuses on the bare lamp performance of 31 linear LED lamps intended as an alternative to T8 fluorescent lamps. Data obtained in accordance with IES LM-79-08 indicated that the mean efficacy is similar to that of fluorescent lamps, but that lumen output is often much lower. This presents a situation where something must change in order for energy savings and equivalent illumination levels to be achieved simultaneously. In this case, the luminous intensity distribution of all the tested lamps was directional or semi-directional, rather than omnidirectional. Also discussed in this report are several issues related to the electrical configuration of the lamps, such as the required socket types and power feed location. While no configuration is necessarily better, the multitude of options can make specifying and installing linear LED lamps more difficult, with the potential for safety issues. Similarly, the variety of color and power quality attributes adds a layer of complexity to the specification process. Many products offered good or excellent quality attributes, but some did not and thus could be perceived as inferior to fluorescent lamps in some installations.

  20. Advance Patent Waiver W(A)2010-034

    Office of Energy Efficiency and Renewable Energy (EERE)

    This is a request by LUMINATION, LLC for a DOE waiver of domestic and foreign patent rights under agreement DE-EE0003232

  1. DOE Publishes CALiPER Report on LED T8 Lamps | Department of...

    Energy Savers [EERE]

    Likewise, some of the LED lamps had similar color quality and power quality to their fluorescent counterparts. But none of the LED products matched the luminous intensity ...

  2. Forest Creek Wind Farm | Open Energy Information

    Open Energy Info (EERE)

    Facility Type Commercial Scale Wind Facility Status In Service Owner E.On Climate & Renewables Developer E.On Climate & RenewablesRGI Energy Purchaser Luminant Location...

  3. Fermi National Accelerator Laboratory February 2015 Particle...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    known as synchrotron light sources to create the brightest light beams on Earth. These luminous sources provide tools for such applications as protein structure analysis,...

  4. NERSC Users Showered With Accolades - NERSC Center News, Apr...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    the expansion history of the universe and tackle questions including the nature of luminous red galaxies, which he calls "problematic for years," using the spectra of the...

  5. Features of primary damage by high energy displacement cascades...

    Office of Scientific and Technical Information (OSTI)

    for ORCID "0000000153327128" ; Lu, Chenyang 2 ; Osetskiy, Yuri N. 1 ; Samolyuk, German D. 1 ; Caro, Alfredo 3 ; Wang, Lumin 2 ; Stoller, Roger E. 1 + Show Author ...

  6. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    ... and phosphor), and has a higher luminance, enabling fixtures to take advantage of the smaller lamp size to improve the optics and provide more efficient overall system illuminance. ...

  7. SSL Selections Descriptions v6.xls

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    General Electric Niskayuna, NY 12309-1027 Optimized Phosphors for Warm-White LED Light Engines. GE Global Research, in collaboration with GE Lumination and the University of ...

  8. Benzobisoxazole cruciforms: A tunable, cross-conjugated platform for the generation of deep blue OLED materials

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Chavez, III, Ramiro; Cai, Min; Tlach, Brian; Wheeler, David L.; Kaudal, Rajiv; Tsyrenova, Ayuna; Tomlinson, Aimee L.; Shinar, Ruth; Shinar, Joseph; Jeffries-EL, Malika

    2016-01-20

    Four new cross-conjugated small molecules based on a central benzo[1,2-d:4,5-d']bisoxazole moiety possessing semi-independently tunable HOMO and LUMO levels were synthesized and the properties of these materials were evaluated experimentally and theoretically. The molecules were thermally stable with 5% weight loss occurring well above 350 °C. The cruciforms all exhibited blue emission in solution ranging from 433–450 nm. Host–guest OLEDs fabricated from various concentrations of these materials using the small molecule host 4,4'-bis(9-carbazolyl)-biphenyl (CBP) exhibited deep blue-emission with Commission Internationale de L'Eclairage (CIE) coordinates of (0.15 ≤ x ≤ 0.17, 0.05 ≤ y ≤ 0.11), and maximum luminance efficiencies as highmore » as ~2 cd A–1. Lastly, these results demonstrate the potential of benzobisoxazole cruciforms as emitters for developing high-performance deep blue OLEDs.« less

  9. Synthesis and electroluminescent properties of anthracene derivatives containing electron-withdrawing oxide moieties

    SciTech Connect (OSTI)

    Yoon, Jhin-yeong; Na, Eun Jae; Park, Soo Na; Lee, Seok Jae; Kim, Young Kwan; Yoon, Seung Soo

    2014-10-15

    Highlights: Blue fluorescent material is important for application in full-color displays. We have synthesized emitters based on anthracene connected with oxide moieties. 1C shows a highly efficient blue EL emission due to electron-injection property. - Abstract: A series of new blue-emitting materials: (4-(10-(naphthalen-2-yl)anthracen-9-yl)phenyl)(phenyl)methanone (1); 9-(naphthalen-2-yl)-10-(4-((diphenyl)phosphine oxide)phenyl)anthracene (2); 9-(naphthalen-2-yl)-10-(4-(phenylsulfonyl)phenyl)anthracene (3) were designed and synthesized via Suzuki cross-coupling reaction. Multilayer OLEDs were fabricated in the following sequence: ITO (180 nm)/NPB (50 nm)/blue materials 13 (30 nm)/TPBi (15 nm)/Liq (2 nm)/Al (100 nm). All devices showed the efficient blue EL emissions. In particular, the device using 1 as an emitter exhibited efficient blue electroluminescent properties with a maximum luminous, power, external quantum efficiency and CIE coordinates of 0.36 cd/A, 0.90 lm/W, 0.55% at 20 mA/cm{sup 2} and (x = 0.16, y = 0.20) at 10.0 V, respectively.

  10. Dopant effects on charge transport to enhance performance of phosphorescent white organic light emitting diodes

    SciTech Connect (OSTI)

    Zhu, Liping; Chen, Jiangshan; Ma, Dongge

    2015-11-07

    We compared the performance of phosphorescent white organic light emitting diodes (WOLEDs) with red-blue-green and green-blue-red sequent emissive layers. It was found that the influence of red and green dopants on electron and hole transport in emissive layers leads to the large difference in the efficiency of fabricated WOLEDs. This improvement mechanism is well investigated by the current density-voltage characteristics of single-carrier devices based on dopant doped emissive layers and the comparison of electroluminescent and photoluminescence spectra, and attributed to the different change of charge carrier transport by the dopants. The optimized device achieves a maximum power efficiency, current efficiency, and external quantum efficiency of 37.0 lm/W, 38.7 cd/A, and 17.7%, respectively, which are only reduced to 32.8 lm/W, 38.5 cd/A, and 17.3% at 1000 cd/m{sup 2} luminance. The critical current density is as high as 210 mA/cm{sup 2}. It can be seen that the efficiency roll-off in phosphorescent WOLEDs can be well improved by effectively designing the structure of emissive layers.

  11. Organic light-emitting devices using spin-dependent processes

    DOE Patents [OSTI]

    Vardeny, Z. Valy; Wohlgenannt, Markus

    2010-03-23

    The maximum luminous efficiency of organic light-emitting materials is increased through spin-dependent processing. The technique is applicable to all electro-luminescent processes in which light is produced by singlet exciton decay, and all devices which use such effects, including LEDs, super-radiant devices, amplified stimulated emission devices, lasers, other optical microcavity devices, electrically pumped optical amplifiers, and phosphorescence (Ph) based light emitting devices. In preferred embodiments, the emissive material is doped with an impurity, or otherwise modified, to increase the spin-lattice relaxation rate (i.e., decrease the spin-lattice time), and hence raise the efficiency of the device. The material may be a polymer, oligomer, small molecule, single crystal, molecular crystal, or fullerene. The impurity is preferably a magnetic or paramagnetic substance. The invention is applicable to IR, UV, and other electromagnetic radiation generation and is thus not limited to the visible region of the spectrum. The methods of the invention may also be combined with other techniques used to improve device performance.

  12. A spectroscopic survey of WISE-selected obscured quasars with the southern african large telescope

    SciTech Connect (OSTI)

    Hainline, Kevin N.; Hickox, Ryan C.; Carroll, Christopher M.; Myers, Adam D.; DiPompeo, Michael A.; Trouille, Laura

    2014-11-10

    We present the results of an optical spectroscopic survey of a sample of 40 candidate obscured quasars identified on the basis of their mid-infrared emission detected by the Wide-Field Infrared Survey Explorer (WISE). Optical spectra for this survey were obtained using the Robert Stobie Spectrograph on the Southern African Large Telescope. Our sample was selected with WISE colors characteristic of active galactic nuclei (AGNs), as well as red optical to mid-IR colors indicating that the optical/UV AGN continuum is obscured by dust. We obtain secure redshifts for the majority of the objects that comprise our sample (35/40), and find that sources that are bright in the WISE W4 (22 μm) band are typically at moderate redshift ((z) = 0.35) while sources fainter in W4 are at higher redshifts ((z) = 0.73). The majority of the sources have narrow emission lines with optical colors and emission line ratios of our WISE-selected sources that are consistent with the locus of AGN on the rest-frame g – z color versus [Ne III] λ3869/[O II] λλ3726+3729 line ratio diagnostic diagram. We also use empirical AGN and galaxy templates to model the spectral energy distributions (SEDs) for the objects in our sample, and find that while there is significant variation in the observed SEDs for these objects, the majority require a strong AGN component. Finally, we use the results from our analysis of the optical spectra and the SEDs to compare our selection criteria to alternate criteria presented in the literature. These results verify the efficacy of selecting luminous obscured AGNs based on their WISE colors.

  13. PROGNOSTICS HEALTH MANAGEMENT MODEL FOR LED PACKAGE FAILURE UNDER CONTAMINATED ENVIRONMENT

    SciTech Connect (OSTI)

    Lall, Pradeep; Zhang, Hao; Davis, J Lynn

    2015-06-06

    The reliability consideration of LED products includes both luminous flux drop and color shift. Previous research either talks about luminous maintenance or color shift, because luminous flux degradation usually takes very long time to observe. In this paper, the impact of a VOC (volatile organic compound) contaminated luminous flux and color stability are examined. As a result, both luminous degradation and color shift had been recorded in a short time. Test samples are white, phosphor-converted, high-power LED packages. Absolute radiant flux is measured with integrating sphere system to calculate the luminous flux. Luminous flux degradation and color shift distance were plotted versus aging time to show the degradation pattern. A prognostic health management (PHM) method based on the state variables and state estimator have been proposed in this paper. In this PHM framework, unscented kalman filter (UKF) was deployed as the carrier of all states. During the estimation process, third order dynamic transfer function was used to implement the PHM framework. Both of the luminous flux and color shift distance have been used as the state variable with the same PHM framework to exam the robustness of the method. Predicted remaining useful life is calculated at every measurement point to compare with the tested remaining useful life. The result shows that state estimator can be used as the method for the PHM of LED degradation with respect to both luminous flux and color shift distance. The prediction of remaining useful life of LED package, made by the states estimator and data driven approach, falls in the acceptable error-bounds (20%) after a short training of the estimator.

  14. Prognostication of LED Remaining Useful Life and Color Stability in the Presence of Contamination

    SciTech Connect (OSTI)

    Lall, Pradeep; Zang, Hao; Davis, J Lynn

    2015-06-22

    The reliability of LED products may be affected by both luminous flux drop and color shift. Previous research on the topic focuses on either luminous maintenance or color shift. However, luminous flux degradation usually takes very long time to observe in LEDs under normal operating conditions. In this paper, the impact of a VOC (volatile organic compound) contaminated luminous flux and color stability are examined. As a result, both luminous degradation and color shift had been recorded in a short time. Test samples are white, phosphorconverted, high-power LED packages. Absolute radiant flux is measured with integrating sphere system to calculate the luminous flux. Luminous flux degradation and color shift distance were plotted versus aging time to show the degradation pattern. A prognostic health management (PHM) method based on the state variables and state estimator have been proposed in this paper. In this PHM framework, unscented kalman filter (UKF) was deployed as the carrier of all states. During the estimation process, third order dynamic transfer function was used to implement the PHM framework. Both of the luminous flux and color shift distance have been used as the state variable with the same PHM framework to exam the robustness of the method. Predicted remaining useful life is calculated at every measurement point to compare with the tested remaining useful life. The result shows that state estimator can be used as the method for the PHM of LED degradation with respect to both luminous flux and color shift distance. The prediction of remaining useful life of LED package, made by the states estimator and data driven approach, falls in the acceptable errorbounds (20%) after a short training of the estimator.

  15. Mechanical and photo-fragmentation processes for nanonization of melanin to improve its efficacy in protecting cells from reactive oxygen species stress

    SciTech Connect (OSTI)

    Liu, Yi-Cheng; Chen, Sih-Min; Liu, Jhong-Han; Hsu, Hsiang-Wei; Lin, Hoang-Yan; Chen, Szu-yuan

    2015-02-14

    It has been well established ex vivo that melanin has the ability of scavenging free radicals and reactive oxygen species (ROS), besides other functions. Therefore, we propose to utilize nanonized melanin as medication against acute oxidative stress. For this purpose, we developed and characterized two techniques based on mechanical stir and photo-fragmentation using femtosecond laser pulses, respectively, for disintegration of suspended melanin powder to produce nanometer-sized and water-dispersible melanin. This resolves a major obstacle in the medical and industrial applications of melanin. The viabilities of cultured retinal pigment epithelium (RPE) cells exposed to exogenous H{sub 2}O{sub 2} stress and treated with various conditions of melanin and irradiation were compared. It was found that melanin could be nanonized very effectively with the techniques, and nanonized melanin exhibited a much stronger effect than unprocessed melanin on raising the viability of cultured RPE cells under acute ROS stress. The effect was even more prominent without simultaneous light irradiation, promising for effective in vivo application to the whole body.

  16. Using ASCEM Modeling and Visualization to Inform Stakeholders of Contaminant Plume Evolution and Remediation Efficacy at F-Basin Savannah River, SC – 15156

    SciTech Connect (OSTI)

    Flach, G.; Wainwright, H.; Molins, S.; Davis, J.; Arora, B.; Faybishenko, B.; Krishnan, H.; Hubbard, S.; Flach, G.; Denham, M.; Eddy-Dilek, C.; Moulton, D.; Lipnikov, K.; Gable, C.; Miller, T.; Freshley, M.

    2015-01-28

    Communication with stakeholders, regulatory agencies, and the public is an essential part of implementing different remediation and monitoring activities, and developing site closure strategies at contaminated sites. Modeling of contaminant plume evolution plays a critical role in estimating the benefit, cost, and risk of particular options. At the same time, effective visualization of monitoring data and modeling results are particularly important for conveying the significance of the results and observations. In this paper, we present the results of the Advanced Simulation Capability for Environmental Management (ASCEM) project, including the discussion of the capabilities of newly developed ASCEM software package, along with its application to the F-Area Seepage Basins located in the U.S. Department of Energy Savannah River Site (SRS). ASCEM software includes state-of-the-art numerical methods for simulating complex flow and reactive transport, as well as various toolsets such as a graphical user interface (GUI), visualization, data management, uncertainty quantification, and parameter estimation. Using this software, we have developed an advanced visualization of tritium plume migration coupled with a data management system, and simulated a three-dimensional model of flow and plume evolution on a high-performance computing platform. We evaluated the effect of engineered flow barriers on a nonreactive tritium plume, through advanced plume visualization and modeling of tritium plume migration. In addition, we developed a geochemical reaction network to describe complex geochemical processes at the site, and evaluated the impact of coupled hydrological and geochemical heterogeneity. These results are expected to support SRS’s monitoring activities and operational decisions.

  17. Efficacy of TACE in TIPS Patients: Comparison of Treatment Response to Chemoembolization for Hepatocellular Carcinoma in Patients With and Without a Transjugular Intrahepatic Portosystemic Shunt

    SciTech Connect (OSTI)

    Kuo, Yuo-Chen Kohi, Maureen P. Naeger, David M. Tong, Ricky T. Kolli, K. Pallav Taylor, Andrew G. Laberge, Jeanne M. Kerlan, Robert K. Fidelman, Nicholas

    2013-10-15

    Purpose: To compare treatment response after transarterial chemoembolization (TACE) for hepatocellular carcinoma (HCC) in patients with and without a transjugular intrahepatic portosystemic shunt (TIPS). Materials and Methods: A retrospective review of patients who underwent conventional TACE for HCC between January 2005 and December 2009 identified 10 patients with patent TIPS. From the same time period, 23 patients without TIPS were selected to control for comparable Model for End-Stage Liver Disease and Child-Pugh-Turcotte scores. The two groups showed similar distribution of Barcelona Clinic Liver Cancer and United Network of Organ Sharing stages. Target HCC lesions were evaluated according to the modified response evaluation criteria in solid tumors (mRECIST) guidelines. Transplantation rate, time to tumor progression, and overall survival (OS) were documented. Results: After TACE, the rate of complete response was significantly greater in non-TIPS patients compared with TIPS patients (74 vs. 30 %, p = 0.03). Objective response rate (complete and partial response) trended greater in the non-TIPS group (83 vs. 50 %, p = 0.09). The liver transplantation rate was 80 and 74 % in the TIPS and non-TIPS groups, respectively (p = 1.0). Time to tumor progression was similar (p = 0.47) between the two groups. OS favored the non-TIPS group (p = 0.01) when censored for liver transplantation. Conclusion: TACE is less effective in achieving complete or partial response using mRECIST criteria in TIPS patients compared with those without a TIPS. Nevertheless, similar clinical outcomes may be achieved, particularly in TIPS patients who are liver-transplantation candidates.

  18. Efficacy of a solution-based approach for making sodalite waste forms for an oxide reduction salt utilized in the reprocessing of used uranium oxide fuel

    SciTech Connect (OSTI)

    Riley, Brian J.; Pierce, David A.; Frank, Steven M.; Matyáš, Josef; Burns, Carolyne A.

    2015-04-01

    This paper describes the various approaches attempted to make solution-derived sodalite with a LiCl-Li2O oxide reduction salt used to dissolve used uranium oxide fuel so the uranium can be recovered and recycled. The approaches include modified sol-gel and solutionbased synthesis processes. As-made products were mixed with 5 and 10 mass% of a Na2O-B2O3- SiO2 glass binder and these, along with product without a binder, were heated using either a cold-press-and-sinter method or hot uniaxial pressing. The results demonstrate the limitation of sodalite yield due to the fast intermediate reactions between Na+ and Cl- to form halite in solution and Li2O and SiO2 to form lithium silicates (e.g., Li2SiO3 or Li2Si2O5) in the calcined and sintered pellets. The results show that pellets can be made with high sodalite fractions in the crystalline product (~92 mass%) and low porosities using a solution-based approach and this LiCl-Li2O salt but that the incorporation of Li into the sodalite is low.

  19. Efficacy of a solution-based approach for making sodalite waste forms for an oxide reduction salt utilized in the reprocessing of used uranium oxide fuel

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Riley, Brian J.; Pierce, David A.; Frank, Steven M.; Matyáš, Josef; Burns, Carolyne A.

    2015-04-01

    This paper describes the various approaches attempted to make solution-derived sodalite with a LiCl-Li2O oxide reduction salt used to dissolve used uranium oxide fuel so the uranium can be recovered and recycled. The approaches include modified sol-gel and solutionbased synthesis processes. As-made products were mixed with 5 and 10 mass% of a Na2O-B2O3- SiO2 glass binder and these, along with product without a binder, were heated using either a cold-press-and-sinter method or hot uniaxial pressing. The results demonstrate the limitation of sodalite yield due to the fast intermediate reactions between Na+ and Cl- to form halite in solution and Li2Omore » and SiO2 to form lithium silicates (e.g., Li2SiO3 or Li2Si2O5) in the calcined and sintered pellets. The results show that pellets can be made with high sodalite fractions in the crystalline product (~92 mass%) and low porosities using a solution-based approach and this LiCl-Li2O salt but that the incorporation of Li into the sodalite is low.« less

  20. Efficacy of a Solution-Based Approach for Making Sodalite Waste Forms for an Oxide Reduction Salt Utilized in the Reprocessing of Used Uranium Oxide Fuel

    SciTech Connect (OSTI)

    Riley, Brian J.; Pierce, David A.; Frank, Steven M.; Matyas, Josef; Burns, Carolyn A.

    2015-04-01

    This paper describes various approaches for making sodalite with a LiCl-Li2O oxide reduction salt used to recover uranium from used oxide fuel. The approaches include sol-gel and solution-based synthesis processes. As-made products were mixed with 5 and 10 mass% of a Na2O-B2O3-SiO2 glass binder and these, along with product without a binder, were heated using either a cold-press-and-sinter method or hot uniaxial pressing. The results demonstrate the limitation of sodalite yield due to the fast intermediate reactions between Na+ and Cl- to form halite in solution and Li2O and SiO2 to form lithium silicates (e.g., Li2SiO3 or Li2Si2O5) in the calcined and sintered pellets. The results show that pellets can be made with high sodalite fractions (~92 mass%) and low porosities using a solution-based approach and this LiCl-Li2O salt.

  1. Assess the Efficacy of an Aerial Distant Observer Tool Capable of Rapid Analysis of Large Sections of Collector Fields: FY 2008 CSP Milestone Report, September 2008

    SciTech Connect (OSTI)

    Jorgensen, G.; Burkholder, F.; Gray, A.; Wendelin, T.

    2009-02-01

    We assessed the feasibility of developing an aerial Distant Observer optical characterization tool for collector fields in concentrating solar power plants.

  2. Pre-clinical studies of toxin-specific Nanobodies: Evidence of in vivo efficacy to prevent fatal disturbances provoked by scorpion envenoming

    SciTech Connect (OSTI)

    Hmila, Issam; Cosyns, Bernard; Tounsi, Hayfa; Roosens, Bram; Caveliers, Vicky; Abderrazek, Rahma Ben; Boubaker, Samir; Muyldermans, Serge; Department of Structural Biology, VIB, Brussels ; El Ayeb, Mohamed; Bouhaouala-Zahar, Balkiss; Facult de Mdecine de Tunis, Universit de Tunis-El Manar ; Lahoutte, Tony

    2012-10-15

    Scorpions represent a significant threat to humans and animals in various countries throughout the world. Recently, we introduced Nanobodies (Nbs) to combat more efficiently scorpion envenoming and demonstrated the performance of NbAahIF12 and NbAahII10 to neutralize scorpion toxins of Androctonus australis hector venom. A bispecific Nb construct (NbF12-10) comprising these two Nbs is far more protective than the classic Fab?{sub 2} based therapy and is the most efficient antivenom therapy against scorpion sting in preclinical studies. Now we investigate the biodistribution and pharmacokinetics of {sup 99m}Tc labeled Nbs by in vivo imaging in rodents and compared these data with those of the Fab?{sub 2} product (PAS). The pharmacodynamics of the Nbs was investigated in rats by in vivo echocardiography and it is shown that NbF12-10 prevents effectively the hemodynamic disturbances induced by a lethal dose of venom. Moreover, even a late injection of NbF12-10 restores the heart rate and brings the blood pressure to baseline values. Histology confirms that NbF12-10 prevents lung and heart lesions of treated mice after envenoming. In conjunction, in this preclinical study, we provide proof of concept that NbF12-10 prevents effectively the fatal disturbances induced by Androctonus venom, and that the Nanobody based therapeutic has a potential to substitute the classic Fab?{sub 2} based product as immunotherapeutic in scorpion envenoming. Further clinical study using larger cohorts of animals should be considered to confirm the full protecting potential of our NbF12-10. -- Highlights: ? Nanobody therapy prevents the hemodynamic disturbances induced by a lethal dose. ? Late injection of Nanobody restores hemodynamic parameters to baseline values. ? Nanobody therapy prevents lung and heart lesions of treated mice after envenoming. ? Labeled Nanobody and Fab2 pharmacokinetics curves reach plateau in favour of Nanobody.

  3. Effect of Hyperoxygenation on Tissue pO{sub 2} and Its Effect on Radiotherapeutic Efficacy of Orthotopic F98 Gliomas

    SciTech Connect (OSTI)

    Khan, Nadeem; Mupparaju, Sriram M.S.; Hekmatyar, Shahryar K.; Hou Huagang; Lariviere, Jean P.; Demidenko, Eugene; Gladstone, David J.; Kauppinen, Risto A.; Swartz, Harold M.

    2010-11-15

    Purpose: Lack of methods for repeated assessment of tumor pO{sub 2} limits the ability to test and optimize hypoxia-modifying procedures being developed for clinical applications. We report repeated measurements of orthotopic F98 tumor pO{sub 2} and relate this to the effect of carbogen inhalation on tumor growth when combined with hypofractionated radiotherapy. Methods and Materials: Electron paramagnetic resonance (EPR) oximetry was used for repeated measurements of tumor and contralateral brain pO{sub 2} in rats during 30% O{sub 2} and carbogen inhalation for 5 consecutive days. The T{sub 1}-enhanced volumes and diffusion coefficients of the tumors were assessed by magnetic resonance imaging (MRI). The tumors were irradiated with 9.3 Gy x 4 fractions in rats breathing 30% O{sub 2} or carbogen to determine the effect on tumor growth. Results: The pretreatment F98 tumor pO{sub 2} varied between 8 and 16 mmHg, while the contralateral brain had 41 to 45 mmHg pO{sub 2} during repeated measurements. Carbogen breathing led to a significant increase in tumor and contralateral brain pO{sub 2}; however, this effect declined over days. Irradiation of the tumors in rats breathing carbogen resulted in a significant decrease in tumor growth and an increase in the diffusion coefficient measured by MRI. Conclusions: The results provide quantitative measurements of the effect of carbogen inhalation on intracerebral tumor pO{sub 2} and its effect on therapeutic outcome. Such direct repeated pO{sub 2} measurements by EPR oximetry can provide temporal information that could be used to improve therapeutic outcome by scheduling doses at times of improved tumor oxygenation. EPR oximetry is currently being tested for clinical applications.

  4. Chief Joseph Kokanee Enhancement Project; Strobe Light Deterrent Efficacy Test and Fish Behavior Determination at Grand Coulee Dam Third Powerplant Forebay, 2005-2006 Annual Report.

    SciTech Connect (OSTI)

    Simmons, M.; Johnson, Robert; McKinstry, C.

    2006-03-01

    The construction of Grand Coulee and Chief Joseph dams on the Columbia River resulted in the complete extirpation of the anadromous fishery upstream of these structures. Today, this area is totally dependent upon resident fish resources to support local fisheries. The resident fishing is enhanced by an extensive stocking program for target species in the existing fishery, including kokanee (Oncorhynchus nerka kennerlyi) and rainbow trout (O. mykiss). The kokanee fishery in Lake Roosevelt has not been meeting the return goals set by fisheries managers despite the stocking program. Investigations of physical and biological factors that could affect the kokanee population found predation and entrainment had a significant impact on the fish population. In 1999 and 2000, walleye (Sander vitreum) consumed between 15% and 9%, respectively, of the hatchery kokanee within 41 days of their release, while results from a study in the late 1990s estimated that entrainment at Grand Coulee Dam could account for up to 30% of the total mortality of the stocked fish. To address the entrainment loss, the Bonneville Power Administration commissioned a study to determine if fish would avoid areas illuminated by strobe lights in the forebay of the third powerplant. This work was conducted by Pacific Northwest National Laboratory (PNNL) in conjunction with the Confederated Tribes of the Colville Reservation (Colville Confederated Tribes). From 2002 through 2004, six strobe lights were suspended in the center of the opening to the third powerplant forebay during summer months. Results from those studies indicated that fish appeared to be attracted to the illuminated area but only at night and when flow conditions within the third powerplant forebay were minimal. However, small but consistent results from these studies indicated that under high flow conditions, fish might be avoiding the lights. The 2005 study was designed to examine whether, under high flow conditions near the penstock openings, fish would avoid the lighted regions. Four omnidirectional strobe lights were deployed on the one trash rack directly in front of one turbine penstock. Seven splitbeam transducers were deployed to monitor fish approaching three penstock openings either from in front of the trash racks or moving down the dam behind the trash racks. Four key results emerged from the 2005 study. The results provide insight into the current level of entrainment and how fish respond to strobe lights under high flow conditions. First, very few fish were detected inside the trash racks. Of the more than 3,200 targets identified by the data processing, less than 100 were detected inside the trash racks. Only 23 fish were found inside the trash racks behind the strobe lights. Of those 21 fish, 13 were detected when the lights were on. Most of the fish detected behind the trash racks were above the turbine penstock but were headed downward. No fish were detected at night when minimal flows occurred between midnight and 4:00 a.m. Second, significantly more fish (P < 0.001) were detected in front of the trash racks when the lights were on at night. On a count-per-hour basis, the difference between lights off and lights on was apparent in the early morning hours at depths between 25 m and 50 m from the transducers. The lights were approximately 34 m below the splitbeam transducers, and fish detected at night with lights on were found at a median depth of approximately 35 m, compared to a median depth of from 20.6 to 23.5 m when the lights were off. The differences in depth between lights on and off at night were also significant (P < 0.001). Additionally, the increase in fish occurred only in front of the trash rack where the strobe lights were mounted; there was no increase in the number of detections by the transducers aimed away from the lights. Third, fish clearly manifested a behavioral response to the strobe lights during the day. When the lights were on, fish detected by three of the four transducers generally were swimming north, parallel to the face of the dam. However, the distribution of swimming directions for fish detected by the transducer immediately to the north of the lights was bimodal, with some fish swimming south toward the lighted region. This behavior was similar to that seen at night when the lights were on. Fourth, kokanee, rainbow trout, and walleye were detected near the strobe lights. Data were obtained from three sources: fish size from the hydroacoustic sensors and fish species from gill netting and video recording. Fish ranging in length from 30 to 600 mm (averaging 125 mm) were detected by the splitbeam transducers. There was little difference in target strength for fish detected above 25 m depth with respect to time of day or light treatment. Below 25 m and closer to the strobe lights, larger fish were present when the lights were on during the night, and smaller fish were present during the day.

  5. Demonstration Assessment of LED Freezer Case Lighting

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... Measurements were taken with a Photo Research Luminance ... The resolution of the loggers was set to a reading level of ... energy road mapping provided by the IES handbook 3 . ...

  6. OLED Lighting Products: Capabilities, Challenges, Potential

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... time there is no testing standard for evaluating and reporting OLED panel life. LM-80-15: IES Approved Method: Measuring Luminous Flux and Color Maintenance of LED Packages, ...

  7. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    XUV-disk galaxies are consistently bluer than the main bodies. We find a surprisingly high frequency of XUV emission around luminous red (NUV-r > 5) and green valley (3 < NUV-r...

  8. Fenestration systems as luminaries of varying candlepower distribution

    SciTech Connect (OSTI)

    Papamichael, K.

    1990-10-01

    Simulation of the performance of electric lighting systems has been successfully handled using computers, since electric lighting systems have a constant luminous output with respect to intensity and spatial distribution, usually referred to as candlepower distribution, which can be measured and used conveniently. This paper describes an approach of treating fenestration systems as luminaries of varying candlepower distribution, so that the determination of their luminous performance becomes consistent with that of electric lighting systems. The transmitted distribution through fenestration systems due to radiation from the sun, sky and ground is determined from their bidirectional transmittance and the luminance distribution of the sources of radiation. The approach is demonstrated using the experimentally determined bidirectional transmittance of a diffusive sample under the uniform, overcast and clear sky luminance distributions. 6 refs., 14 figs.

  9. Press Pass - Press Releases

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    knew they had found something unusual, neither supernova nor quasar but a "highly luminous optical transient." "When we saw that it had faded so much, we knew it couldn't...

  10. Structure, Inhibition and Regulation of Two-pore Channel TPC1...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    a, Top view from the luminal side onto the membrane plane and b, side view from the right side with the perpendicular to the membrane plane vertical of the TPC1 structure labeled ...

  11. Enol Intermediates Unexpectedly Found in Flames

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    by a crossed tunable VUV beam. Photoions are mass-analyzed using a time-of-flight (TOF) mass spectrometer (MS). The luminous zone of the flame shown here (just to left...

  12. Technology makes reds "pop" in LED displays | GE Global Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Reveal and Energy Smart consumer brands, and Evolve(tm), GTx(tm), Immersion(tm), Infusion(tm), Lumination(tm), Albeo(tm) and Tetra commercial brands, all trademarks of GE....

  13. The Momentum of Light - B

    Office of Scientific and Technical Information (OSTI)

    B. Are energy quanta also momentum quanta? Einstein's review was similar to his 1905 analysis of energy quanta. In that work, he had considered a furnace containing hot, luminous ...

  14. Modelling breast cancer requires identification and correction of a critical cell lineage-dependent transduction bias

    SciTech Connect (OSTI)

    Hines, William C.; Yaswen, Paul; Bissell, Mina J.

    2015-04-21

    When trying to explore the biology and etiology of human cancers, clinically relevant human culture models are essential. Current breast tumour models, such as those from oncogenically transformed primary breast cells, produce predominantly basal-like properties, whereas the more common phenotype expressed by the vast majority of breast tumours are luminal. Reasons for this puzzling, yet important phenomenon, are not understood. We show here that luminal epithelial cells are significantly more resistant to viral transduction than their myoepithelial counterparts. Here, we suggest that this is a significant barrier to generating luminal cell lines and experimental tumours in vivo and to accurate interpretation of results. We show that the resistance is due to lower affinity of luminal cells for virus attachment, which can be overcome by pretreating cells—or virus—with neuraminidase. We present an analytical method for quantifying transductional differences between cell types and an optimized protocol for transducing unsorted primary human breast cells in context.

  15. Search for: All records | SciTech Connect

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    ... p68) is involved in all aspects of RNA metabolism and serves as a transcriptional ... We showed that protein expression of DDX5 increased progressively from the luminal to ...

  16. Computing

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... located about 10,000 light years away in the host galaxy of the supernova. (Credit: Beijing Planetarium Jin Ma) Machine learning helps discover the most luminous supernova in ...

  17. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    ... during luminal perfusion with FMLP. The specific elastase inhibitors MeOSuc-Ala-Ala-Pro-Val-CHsub 2Cl (10 mgkg) and Eglin c (8 mgkg) significantly attenuated the ...

  18. 1

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    helps discover the most luminous supernova in history January 14, 2016 Powerful explosion 570 billion times brighter than the sun LOS ALAMOS, N.M., Jan. 14, 2016-Machine-learning technology developed at Los Alamos National Laboratory played a key role in the discovery of supernova ASASSN-15lh, an exceptionally powerful explosion that was 570 billion times brighter than the sun and more than twice as luminous as the previous record-holding supernova. This extraordinary event marking the death of

  19. He II {lambda}4686 IN {eta} CARINAE: COLLAPSE OF THE WIND-WIND COLLISION REGION DURING PERIASTRON PASSAGE

    SciTech Connect (OSTI)

    Teodoro, M.; Damineli, A.; Arias, J. I.; De Araujo, F. X.; Borges Fernandes, M.; Pereira, C. B.; Barba, R. H.; Gonzalez, J. F.; Corcoran, M. F.; Marshall, J. L.; McGregor, P. J.; Nicholls, D. C.; Parkin, E. R.; Morrell, N.; Phillips, M. M.; and others

    2012-02-10

    The periodic spectroscopic events in {eta} Carinae are now well established and occur near the periastron passage of two massive stars in a very eccentric orbit. Several mechanisms have been proposed to explain the variations of different spectral features, such as an eclipse by the wind-wind collision (WWC) boundary, a shell ejection from the primary star or accretion of its wind onto the secondary. All of them have problems explaining all the observed phenomena. To better understand the nature of the cyclic events, we performed a dense monitoring of {eta} Carinae with five Southern telescopes during the 2009 low-excitation event, resulting in a set of data of unprecedented quality and sampling. The intrinsic luminosity of the He II {lambda}4686 emission line (L {approx} 310 L{sub Sun }) just before periastron reveals the presence of a very luminous transient source of extreme UV radiation emitted in the WWC region. Clumps in the primary's wind probably explain the flare-like behavior of both the X-ray and He II {lambda}4686 light curves. After a short-lived minimum, He II {lambda}4686 emission rises again to a new maximum, when X-rays are still absent or very weak. We interpret this as a collapse of the WWC onto the 'surface' of the secondary star, switching off the hard X-ray source and diminishing the WWC shock cone. The recovery from this state is controlled by the momentum balance between the secondary's wind and the clumps in the primary's wind.

  20. PS1-10jh: The disruption of a main-sequence star of near-solar composition

    SciTech Connect (OSTI)

    Guillochon, James; Manukian, Haik; Ramirez-Ruiz, Enrico

    2014-03-01

    When a star comes within a critical distance to a supermassive black hole (SMBH), immense tidal forces disrupt the star, resulting in a stream of debris that falls back onto the SMBH and powers a luminous flare. In this paper, we perform hydrodynamical simulations of the disruption of a main-sequence star by an SMBH to characterize the evolution of the debris stream after a tidal disruption. We demonstrate that this debris stream is confined by self-gravity in the two directions perpendicular to the original direction of the star's travel and as a consequence has a negligible surface area and makes almost no contribution to either the continuum or line emission. We therefore propose that any observed emission lines are not the result of photoionization in this unbound debris, but are produced in the region above and below the forming elliptical accretion disk, analogous to the broad-line region (BLR) in steadily accreting active galactic nuclei. As each line within a BLR is observationally linked to a particular location in the accretion disk, we suggest that the absence of a line indicates that the accretion disk does not yet extend to the distance required to produce that line. This model can be used to understand the spectral properties of the tidal disruption event PS1-10jh, for which He II lines are observed, but the Balmer series and He I are not. Using a maximum likelihood analysis, we show that the disruption of a main-sequence star of near-solar composition can reproduce this event.

  1. METALLICITY GRADIENT OF A LENSED FACE-ON SPIRAL GALAXY AT REDSHIFT 1.49

    SciTech Connect (OSTI)

    Yuan, T.-T.; Kewley, L. J.; Swinbank, A. M.; Richard, J.; Livermore, R. C.

    2011-05-01

    We present the first metallicity gradient measurement for a grand-design face-on spiral galaxy at z {approx} 1.5. This galaxy has been magnified by a factor of 22x by a massive, X-ray luminous galaxy cluster MACS J1149.5+2223 at z = 0.544. Using the Laser Guide Star Adaptive Optics aided integral field spectrograph OSIRIS on KECK II, we target the H{alpha} emission and achieve a spatial resolution of 0.''1, corresponding to a source-plane resolution of 170 pc. The galaxy has well-developed spiral arms and the nebular emission line dynamics clearly indicate a rotationally supported disk with V{sub rot}/{sigma} {approx} 4. The best-fit disk velocity field model yields a maximum rotation of V{sub rot}sin i = 150 {+-} 15 km s{sup -1}, and a dynamical mass of M{sub dyn} = (1.3 {+-} 0.2) x 10{sup 10} cosec{sup 2}(i) M{sub sun} (within 2.5 kpc), where the inclination angle i = 45{sup 0} {+-} 10{sup 0}. Based on the [N II] and H{alpha} ratios, we measured the radial chemical abundance gradient from the inner hundreds of parsecs out to {approx}5 kpc. The slope of the gradient is -0.16 {+-} 0.02 dex kpc{sup -1}, significantly steeper than the gradient of late-type or early-type galaxies in the local universe. If representative of disk galaxies at z {approx} 1.5, our results support an 'inside-out' disk formation scenario in which early infall/collapse in the galaxy center builds a chemically enriched nucleus, followed by slow enrichment of the disk over the next 9 Gyr.

  2. A test of the millisecond magnetar central engine model of gamma-ray bursts with swift data

    SciTech Connect (OSTI)

    L, Hou-Jun; Zhang, Bing, E-mail: lhj@physics.unlv.edu, E-mail: zhang@physics.unlv.edu [Department of Physics and Astronomy, University of Nevada Las Vegas, Las Vegas, NV 89154 (United States)

    2014-04-10

    A rapidly spinning, strongly magnetized neutron star (magnetar) has been proposed as one possible candidate of the central engine of gamma-ray bursts (GRBs). We systematically analyze the Swift/XRT light curves of long GRBs detected before 2013 August, and characterize them into four categories based on how likely they may harbor a magnetar central engine: Gold, Silver, Aluminum, and Non-magnetar. We also independently analyze the data of short GRBs with a putative magnetar central engine. We then perform a statistical study of various properties of the magnetar samples and the non-magnetar sample, and investigate whether the data are consistent with the hypothesis that there exist two types of central engines. By deriving the physical parameters of the putative magnetars, we find that the observations of the Gold and Silver samples are generally consistent with the predictions of the magnetar model. For a reasonable beaming factor for long GRBs, the derived magnetar surface magnetic field B{sub p} and initial spin period P {sub 0} fall into the reasonable range. Magnetar winds in short GRBs, on the other hand, are consistent with being isotropic. No GRB in the magnetar sample has a beam-corrected total energy exceeding the maximum energy budget defined by the initial spin energy of the magnetar, while some non-magnetar GRBs do violate such a limit. With beaming correction, on average the non-magnetar sample is more energetic and luminous than the magnetar samples. Our analysis hints that millisecond magnetars are likely operating in a good fraction, but probably not all, GRBs.

  3. STEPS TOWARD UNVEILING THE TRUE POPULATION OF ACTIVE GALACTIC NUCLEI: PHOTOMETRIC CHARACTERIZATION OF ACTIVE GALACTIC NUCLEI IN COSMOS

    SciTech Connect (OSTI)

    Schneider, Evan E.; Impey, Christopher D.; Trump, Jonathan R.

    2013-04-01

    Using a physically motivated, model-based active galactic nucleus (AGN) characterization technique, we fit a large sample of X-ray-selected AGNs with known spectroscopic redshifts from the Cosmic Evolution Survey field. We identify accretion disks in the spectral energy distributions of broad- and narrow-line AGNs, and infer the presence or absence of host galaxy light in the SEDs. Based on infrared and UV excess AGN selection techniques, our method involves fitting a given SED with a model consisting of three components: infrared power-law emission, optical-UV accretion disk emission, and host galaxy emission. Each component can be varied in relative contribution, and a reduced chi-square minimization routine is used to determine the optimum parameters for each object. Using this technique, both broad- and narrow-line AGNs fall within well-defined and plausible bounds on the physical parameters of the model, allowing trends with luminosity and redshift to be determined. In particular, based on our sample of spectroscopically confirmed AGNs, we find that approximately 95% of the broad-line AGNs and 50% of the narrow-line AGNs in our sample show evidence of an accretion disk, with maximum disk temperatures ranging from 1 to 10 eV. Because this fitting technique relies only on photometry, we hope to apply it in future work to the characterization and eventually the selection of fainter AGNs than are accessible in wide-field spectroscopic surveys, and thus probe a population of less luminous and/or higher redshift objects without prior redshift or X-ray data. With the abundant availability of photometric data from large surveys, the ultimate goal is to use this technique to create large samples that will complement and complete AGN catalogs selected by X-ray emission alone.

  4. Grating formation by a high power radio wave in near-equator ionosphere

    SciTech Connect (OSTI)

    Singh, Rohtash; Sharma, A. K.; Tripathi, V. K.

    2011-11-15

    The formation of a volume grating in the near-equator regions of ionosphere due to a high power radio wave is investigated. The radio wave, launched from a ground based transmitter, forms a standing wave pattern below the critical layer, heating the electrons in a space periodic manner. The thermal conduction along the magnetic lines of force inhibits the rise in electron temperature, limiting the efficacy of heating to within a latitude of few degrees around the equator. The space periodic electron partial pressure leads to ambipolar diffusion creating a space periodic density ripple with wave vector along the vertical. Such a volume grating is effective to cause strong reflection of radio waves at a frequency one order of magnitude higher than the maximum plasma frequency in the ionosphere. Linearly mode converted plasma wave could scatter even higher frequency radio waves.

  5. Demonstration Assessment of LED Roadway Lighting: NE Cully Boulevard Portland, OR

    SciTech Connect (OSTI)

    Royer, Michael P.; Poplawski, Michael E.; Tuenge, Jason R.

    2012-06-29

    A new roadway lighting demonstration project was initiated in late 2010, which was planned in conjunction with other upgrades to NE Cully Boulevard, a residential collector road in the northeast area of Portland, OR. With the NE Cully Boulevard project, the Portland Bureau of Transportation hoped to demonstrate different light source technologies and different luminaires side-by-side. This report documents the initial performance of six different newly installed luminaires, including three LED products, one induction product, one ceramic metal halide product, and one high-pressure sodium (HPS) product that represented the baseline solution. It includes reported, calculated, and measured performance; evaluates the economic feasibility of each of the alternative luminaires; and documents user feedback collected from a group of local Illuminating Engineering Society (IES) members that toured the site. This report does not contain any long-term performance evaluations or laboratory measurements of luminaire performance. Although not all of the installed products performed equally, the alternative luminaires generally offered higher efficacy, more appropriate luminous intensity distributions, and favorable color quality when compared to the baseline HPS luminaire. However, some products did not provide sufficient illumination to all areas—vehicular drive lanes, bicycle lanes, and sidewalks—or would likely fail to meet design criteria over the life of the installation due to expected depreciation in lumen output. While the overall performance of the alternative luminaires was generally better than the baseline HPS luminaire, cost remains a significant barrier to widespread adoption. Based on the cost of the small quantity of luminaires purchased for this demonstration, the shortest calculated payback period for one of the alternative luminaire types was 17.3 years. The luminaire prices were notably higher than typical prices for currently available luminaires

  6. Energy Efficiency of LEDs

    SciTech Connect (OSTI)

    2013-03-01

    Solid-state lighting program technology fact sheet on energy efficiency of LEDs, characterizing the current state of the market and discussing package efficacy, luminaire efficacy, and application efficacy.

  7. Is Biological Subtype Prognostic of Locoregional Recurrence Risk in Women With pT1-2N0 Breast Cancer Treated With Mastectomy?

    SciTech Connect (OSTI)

    Truong, Pauline T.; Sadek, Betro T.; Lesperance, Maria F.; Alexander, Cheryl S.; Shenouda, Mina; Raad, Rita Abi; Taghian, Alphonse G.

    2014-01-01

    Purpose: To examine locoregional and distant recurrence (LRR and DR) in women with pT1-2N0 breast cancer according to approximated subtype and clinicopathologic characteristics. Methods and Materials: Two independent datasets were pooled and analyzed. The study participants were 1994 patients with pT1-2N0M0 breast cancer, treated with mastectomy without radiation therapy. The patients were classified into 1 of 5 subtypes: luminal A (ER+ or PR+/HER 2?/grade 1-2, n=1202); luminal B (ER+ or PR+/HER 2?/grade 3, n=294); luminal HER 2 (ER+ or PR+/HER 2+, n=221); HER 2 (ER?/PR?/HER 2+, n=105) and triple-negative breast cancer (TNBC) (ER?/PR?/HER 2?, n=172). Results: The median follow-up time was 4.3 years. The 5-year Kaplan-Meier (KM) LRR were 1.8% in luminal A, 3.1% in luminal B, 1.7% in luminal HER 2, 1.9% in HER 2, and 1.9% in TNBC cohorts (P=.81). The 5-year KM DR was highest among women with TNBC: 1.8% in luminal A, 5.0% in luminal B, 2.4% in luminal HER 2, 1.1% in HER 2, and 9.6% in TNBC cohorts (P<.001). Among 172 women with TNBC, the 5-year KM LRR were 1.3% with clear margins versus 12.5% with close or positive margins (P=.04). On multivariable analysis, factors that conferred higher LRR risk were tumors >2 cm, lobular histology, and close/positive surgical margins. Conclusions: The 5-year risk of LRR in our pT1-2N0 cohort treated with mastectomy was generally low, with no significant differences observed between approximated subtypes. Among the subtypes, TNBC conferred the highest risk of DR and an elevated risk of LRR in the presence of positive or close margins. Our data suggest that although subtype alone cannot be used as the sole criterion to offer postmastectomy radiation therapy, it may reasonably be considered in conjunction with other clinicopathologic factors including tumor size, histology, and margin status. Larger cohorts and longer follow-up times are needed to define which women with node-negative disease have high postmastectomy LRR risks in

  8. Retail Lamps Study 3.1: Dimming, Flicker, and Power Quality Characteristics of LED A Lamps.

    SciTech Connect (OSTI)

    Royer, Michael P.; Poplawski, Michael E.; Brown, Charles C.

    2014-12-14

    To date, all three reports in the retail lamps series have focused on basic performance parameters, such as lumen output, efficacy, and color quality. This report goes a step further, examining the photoelectric characteristics (i.e., dimming and flicker) of a subset of lamps from CALiPER Retails Lamps Study 3. Specifically, this report focuses on the dimming, power quality, and flicker characteristics of 14 LED A lamps, as controlled by four different retail-available dimmers. The results demonstrate notable variation across the various lamps, but little variation between the four dimmers. Overall, the LED lamps: ~tended to have higher relative light output compared to the incandescent and halogen benchmark at the same dimmer output signal (RMS voltage). The lamps’ dimming curves (i.e., the relationship between control signal and relative light output) ranged from linear to very similar to the square-law curve typical of an incandescent lamp. ~generally exhibited symmetrical behavior—the same dimming curve—when measured proceeding from maximum to minimum or minimum to maximum control signal. ~mostly dimmed below 10% of full light output, with some exceptions for specific lamp and dimmer combinations ~exhibited a range of flicker characteristics, with many comparing favorably to the level typical of a magnetically-ballasted fluorescent lamp through at least a majority of the dimming range. ~ always exceeded the relative (normalized) efficacy over the dimming range of the benchmark lamps, which rapidly decline in efficacy when they are dimmed. This report generally does not attempt to rank the performance of one product compared to another, but instead focuses on the collective performance of the group versus conventional incandescent or halogen lamps, the performance of which is likely to be the baseline for a majority of consumers. Undoubtedly, some LED lamps perform better—or more similar to conventional lamps—than others. Some perform desirably for one

  9. Intensity inhomogeneity correction for magnetic resonance imaging of human brain at 7T

    SciTech Connect (OSTI)

    Uwano, Ikuko; Yamashita, Fumio; Higuchi, Satomi; Ito, Kenji; Sasaki, Makoto; Kudo, Kohsuke Goodwin, Jonathan; Harada, Taisuke; Ogawa, Akira

    2014-02-15

    Purpose: To evaluate the performance and efficacy for intensity inhomogeneity correction of various sequences of the human brain in 7T MRI using the extended version of the unified segmentation algorithm. Materials: Ten healthy volunteers were scanned with four different sequences (2D spin echo [SE], 3D fast SE, 2D fast spoiled gradient echo, and 3D time-of-flight) by using a 7T MRI system. Intensity inhomogeneity correction was performed using the “New Segment” module in SPM8 with four different values (120, 90, 60, and 30 mm) of full width at half maximum (FWHM) in Gaussian smoothness. The uniformity in signals in the entire white matter was evaluated using the coefficient of variation (CV); mean signal intensities between the subcortical and deep white matter were compared, and contrast between subcortical white matter and gray matter was measured. The length of the lenticulostriate (LSA) was measured on maximum intensity projection (MIP) images in the original and corrected images. Results: In all sequences, the CV decreased as the FWHM value decreased. The differences of mean signal intensities between subcortical and deep white matter also decreased with smaller FWHM values. The contrast between white and gray matter was maintained at all FWHM values. LSA length was significantly greater in corrected MIP than in the original MIP images. Conclusions: Intensity inhomogeneity in 7T MRI can be successfully corrected using SPM8 for various scan sequences.

  10. Moisture exposure to different layers in organic light-emitting diodes and the effect on electroluminescence characteristics

    SciTech Connect (OSTI)

    Liao, L. S.; Tang, C. W.

    2008-08-15

    Moisture effect on electroluminescence characteristics, including current density versus voltage, luminance versus voltage, luminous efficiency versus current density, dark spot formation, and operational stability of organic light-emitting diodes, has been systematically investigated by exposing each layer of the devices to moisture at room temperature. Moisture has a different effect on each of the interfaces or surfaces, and the influence increases as exposure time increases. There is a slight effect on the electroluminescence characteristics after the anode surface has been exposed to moisture. However, severe luminance decrease, dark spot formation, and operational stability degradation take place after the light-emitting layer or the electron-transporting layer is exposed to moisture. It is also demonstrated that the effect of moisture can be substantially reduced if the exposure to moisture is in a dark environment.

  11. A Treatment Planning Method for Sequentially Combining Radiopharmaceutical Therapy and External Radiation Therapy;External beam therapy; Radiopharmaceutical therapy; Three-dimensional dosimetry; Treatment planning

    SciTech Connect (OSTI)

    Hobbs, Robert F.; McNutt, Todd; Baechler, Sebastien; He Bin; Esaias, Caroline E.; Frey, Eric C.; Loeb, David M.; Wahl, Richard L.; Shokek, Ori; Sgouros, George

    2011-07-15

    Purpose: Effective cancer treatment generally requires combination therapy. The combination of external beam therapy (XRT) with radiopharmaceutical therapy (RPT) requires accurate three-dimensional dose calculations to avoid toxicity and evaluate efficacy. We have developed and tested a treatment planning method, using the patient-specific three-dimensional dosimetry package 3D-RD, for sequentially combined RPT/XRT therapy designed to limit toxicity to organs at risk. Methods and Materials: The biologic effective dose (BED) was used to translate voxelized RPT absorbed dose (D{sub RPT}) values into a normalized total dose (or equivalent 2-Gy-fraction XRT absorbed dose), NTD{sub RPT} map. The BED was calculated numerically using an algorithmic approach, which enabled a more accurate calculation of BED and NTD{sub RPT}. A treatment plan from the combined Samarium-153 and external beam was designed that would deliver a tumoricidal dose while delivering no more than 50 Gy of NTD{sub sum} to the spinal cord of a patient with a paraspinal tumor. Results: The average voxel NTD{sub RPT} to tumor from RPT was 22.6 Gy (range, 1-85 Gy); the maximum spinal cord voxel NTD{sub RPT} from RPT was 6.8 Gy. The combined therapy NTD{sub sum} to tumor was 71.5 Gy (range, 40-135 Gy) for a maximum voxel spinal cord NTD{sub sum} equal to the maximum tolerated dose of 50 Gy. Conclusions: A method that enables real-time treatment planning of combined RPT-XRT has been developed. By implementing a more generalized conversion between the dose values from the two modalities and an activity-based treatment of partial volume effects, the reliability of combination therapy treatment planning has been expanded.

  12. 1,"W A Parish","Coal","NRG Texas Power LLC",3675 2,"South Texas Project","Nuclear","STP Nuclear Operating Co",2560

    U.S. Energy Information Administration (EIA) Indexed Site

    Texas" ,"Plant","Primary energy source","Operating company","Net summer capacity (MW)" 1,"W A Parish","Coal","NRG Texas Power LLC",3675 2,"South Texas Project","Nuclear","STP Nuclear Operating Co",2560 3,"Martin Lake","Coal","Luminant Generation Company LLC",2410 4,"Comanche Peak","Nuclear","Luminant Generation Company LLC",2400

  13. Optical devices

    DOE Patents [OSTI]

    Chaves, Julio C.; Falicoff, Waqidi; Minano, Juan C.; Benitez, Pablo; Dross, Oliver; Parkyn, Jr., William A.

    2010-07-13

    An optical manifold for efficiently combining a plurality of blue LED outputs to illuminate a phosphor for a single, substantially homogeneous output, in a small, cost-effective package. Embodiments are disclosed that use a single or multiple LEDs and a remote phosphor, and an intermediate wavelength-selective filter arranged so that backscattered photoluminescence is recycled to boost the luminance and flux of the output aperture. A further aperture mask is used to boost phosphor luminance with only modest loss of luminosity. Alternative non-recycling embodiments provide blue and yellow light in collimated beams, either separately or combined into white.

  14. Optical manifold for light-emitting diodes

    DOE Patents [OSTI]

    Chaves, Julio C.; Falicoff, Waqidi; Minano, Juan C.; Benitez, Pablo; Parkyn, Jr., William A.; Alvarez, Roberto; Dross, Oliver

    2008-06-03

    An optical manifold for efficiently combining a plurality of blue LED outputs to illuminate a phosphor for a single, substantially homogeneous output, in a small, cost-effective package. Embodiments are disclosed that use a single or multiple LEDs and a remote phosphor, and an intermediate wavelength-selective filter arranged so that backscattered photoluminescence is recycled to boost the luminance and flux of the output aperture. A further aperture mask is used to boost phosphor luminance with only modest loss of luminosity. Alternative non-recycling embodiments provide blue and yellow light in collimated beams, either separately or combined into white.

  15. THE AVERAGE PHYSICAL PROPERTIES AND STAR FORMATION HISTORIES OF THE UV-BRIGHTEST STAR-FORMING GALAXIES AT z {approx} 3.7

    SciTech Connect (OSTI)

    Lee, Kyoung-Soo; Glikman, Eilat; Dey, Arjun; Reddy, Naveen; Jannuzi, Buell T.; Brown, Michael J. I.; Gonzalez, Anthony H.; Cooper, Michael C.; Fan Xiaohui; Bian Fuyan; Stern, Daniel; Brodwin, Mark; Cooray, Asantha

    2011-06-01

    We investigate the average physical properties and star formation histories (SFHs) of the most UV-luminous star-forming galaxies at z {approx} 3.7. Our results are based on the average spectral energy distributions (SEDs), constructed from stacked optical-to-infrared photometry, of a sample of the 1913 most UV-luminous star-forming galaxies found in 5.3 deg{sup 2} of the NOAO Deep Wide-Field Survey. We find that the shape of the average SED in the rest optical and infrared is fairly constant with UV luminosity, i.e., more UV-luminous galaxies are, on average, also more luminous at longer wavelengths. In the rest UV, however, the spectral slope {beta} ({identical_to} dlogF{sub {lambda}}/dlog{lambda}; measured at 0.13 {mu}m < {lambda}{sub rest} < 0.28 {mu}m) rises steeply with the median UV luminosity from -1.8 at L {approx} L* to -1.2 (L {approx} 4-5L*). We use population synthesis analyses to derive their average physical properties and find that (1) L{sub UV} and thus star formation rates (SFRs) scale closely with stellar mass such that more UV-luminous galaxies are also more massive, (2) the median ages indicate that the stellar populations are relatively young (200-400 Myr) and show little correlation with UV luminosity, and (3) more UV-luminous galaxies are dustier than their less-luminous counterparts, such that L {approx} 4-5L* galaxies are extincted up to A(1600) = 2 mag while L {approx} L* galaxies have A(1600) = 0.7-1.5 mag. We argue that the average SFHs of UV-luminous galaxies are better described by models in which SFR increases with time in order to simultaneously reproduce the tight correlation between the UV-derived SFR and stellar mass and their universally young ages. We demonstrate the potential of measurements of the SFR-M{sub *} relation at multiple redshifts to discriminate between simple models of SFHs. Finally, we discuss the fate of these UV-brightest galaxies in the next 1-2 Gyr and their possible connection to the most massive galaxies at

  16. Red emission phosphor for real-time skin dosimeter for fluoroscopy and interventional radiology

    SciTech Connect (OSTI)

    Nakamura, Masaaki Chida, Koichi; Zuguchi, Masayuki

    2014-10-15

    Purpose: There are no effective real-time direct skin dosimeters for interventional radiology. Such a scintillation dosimeter would be available if there was a suitable red emission phosphor in the medical x-ray range, since the silicon photodiode is a highly efficient device for red light. However, it is unknown whether there is a suitable red emission phosphor. The purpose of this study is to find a suitable red emission phosphor that can be used in x-ray dosimeters. Methods: Five kinds of phosphors which emit red light when irradiated with electron beams or ultraviolet rays in practical devices were chosen. For the brightness measurement, phosphor was put into transparent plastic cells or coated onto plastic sheets. The phosphors were irradiated with medical range x-rays [60–120 kV(peak), maximum dose rate of 160 mGy min{sup −1}], and the emission was measured by a luminance meter. Several characteristics, such as brightness, dose rate dependence, tube voltage dependence, and brightness stability, were investigated. Results: The luminescence of Y V O{sub 4}:Eu, (Y,Gd,Eu) BO{sub 3}, and Y{sub 2}O{sub 3}:Eu significantly deteriorated by 5%–10% when irradiated with continuous 2 Gy x-rays. The 0.5MgF{sub 2}⋅3.5MgO⋅GeO{sub 2}:Mn phosphor did not emit enough. Only the Y{sub 2}O{sub 2}S:Eu,Sm phosphor had hardly any brightness deterioration, and it had a linear relationship so that the x-ray dose rate could be determined from the brightness with sufficient accuracy. For the tube voltage dependence of the Y{sub 2}O{sub 2}S:Eu,Sm phosphor, the brightness per unit dose rate with 120 kV(peak) x-rays was 30% higher than that with 60 kV(peak) x-rays. Conclusions: Five kinds of phosphors were chosen as an x-ray scintillator for a real-time direct skin dosimeter. The Y V O{sub 4}:Eu, (Y,Gd,Eu)BO{sub 3}, and Y{sub 2}O{sub 3}:Eu phosphors had brightness deterioration caused by the x-rays. Only the Y{sub 2}O{sub 2}S:Eu,Sm phosphor had hardly any brightness deterioration

  17. CALiPER Retail Lamps Study 3

    SciTech Connect (OSTI)

    Royer, Michael P.; Beeson, Tracy A.

    2014-02-01

    uses, such as in enclosed luminaires, may require more development. At the same price point, lamps purchased in 2013 tended to have higher output and slightly higher efficacy than in 2011 or 2010. Over 30% of the products purchased in 2013 exceeded the maximum efficacy measured in 2011 (71 lm/W), with the most efficacious product measured at 105 lm/W. There appears to be increasing consistency in color quality, with a vast majority of products having a CCT of 2700 K or 3000 K and a CRI between 80 and 85. There were also fewer poor performing products tested and more high-performing products available in 2013 than in previous years. The accuracy of equivalency and performance claims was better than in 2011, but remains a concern, with 43% of tested products failing to completely meet their equivalency claim and 20% of products failing to match the manufacturer’s performance data. Although progress has been substantial, on average LED lamps remain more expensive than other energy efficiency lighting technologies -- although some aspects can be superior. Although not universal to all product lines or all product types, the issue of insufficient lumen output from LED lamps is waning. Thus, manufacturers can focus on other issues, such as reducing cost, improving electrical/dimmer compatibility, eliminating flicker, or improving color quality. While these issues are not inherent to all products, they remain a concern for the broader market.

  18. Exploring Flicker in Solid State Lighting: What you Might Find, and How to Deal With It

    SciTech Connect (OSTI)

    Poplawski, Michael E.; Miller, Naomi J.

    2011-12-16

    This paper presents the measured flicker found in a variety of traditional lighting technology products, as well as a sample of commercially available SSL products, and addresses the question of whether SSL sources modulate luminous flux any differently than the traditional sources the lighting industry has been built on.

  19. Imaging the environment of a z = 6.3 submillimeter galaxy with SCUBA-2

    SciTech Connect (OSTI)

    Robson, E. I.; Holland, W. S.; Ivison, R. J.; Smail, Ian; Geach, J. E.; Gibb, A. G.; Riechers, D.; Ade, P. A. R.; Bintley, D.; Bock, J.; Chapin, E. L.; Chapman, S. C.; Clements, D. L.; Conley, A.; Cooray, A.; Dunlop, J. S.; Farrah, D.; and others

    2014-09-20

    We describe a search for submillimeter emission in the vicinity of one of the most distant, luminous galaxies known, HerMES FLS3, at z = 6.34, exploiting it as a signpost to a potentially biased region of the early universe, as might be expected in hierarchical structure formation models. Imaging to the confusion limit with the innovative, wide-field submillimeter bolometer camera, SCUBA-2, we are sensitive to colder and/or less luminous galaxies in the surroundings of HFLS3. We use the Millennium Simulation to illustrate that HFLS3 may be expected to have companions if it is as massive as claimed, but find no significant evidence from the surface density of SCUBA-2 galaxies in its vicinity, or their colors, that HFLS3 marks an overdensity of dusty, star-forming galaxies. We cannot rule out the presence of dusty neighbors with confidence, but deeper 450 ?m imaging has the potential to more tightly constrain the redshifts of nearby galaxies, at least one of which likely lies at z ? 5. If associations with HFLS3 can be ruled out, this could be taken as evidence that HFLS3 is less biased than a simple extrapolation of the Millennium Simulation may imply. This could suggest either that it represents a rare short-lived, but highly luminous, phase in the evolution of an otherwise typical galaxy, or that this system has suffered amplification due to a foreground gravitational lens and so is not as intrinsically luminous as claimed.

  20. Using prismatic microstructured films for image blending in OLEDS

    DOE Patents [OSTI]

    Haenichen, Lukas; Pschenitzka, Florian

    2009-09-08

    An apparatus such as a light source is disclosed which has an OLED device and a microstructured film disposed on the substrate or transparent electrode of said OLED device and on the exterior of said OLED device. The microstructured film contains features which diffuse light emitted by said OLED device and increase the luminance of the device.

  1. Modelling breast cancer requires identification and correction of a critical cell lineage-dependent transduction bias

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Hines, William C.; Yaswen, Paul; Bissell, Mina J.

    2015-04-21

    When trying to explore the biology and etiology of human cancers, clinically relevant human culture models are essential. Current breast tumour models, such as those from oncogenically transformed primary breast cells, produce predominantly basal-like properties, whereas the more common phenotype expressed by the vast majority of breast tumours are luminal. Reasons for this puzzling, yet important phenomenon, are not understood. We show here that luminal epithelial cells are significantly more resistant to viral transduction than their myoepithelial counterparts. Here, we suggest that this is a significant barrier to generating luminal cell lines and experimental tumours in vivo and to accuratemore » interpretation of results. We show that the resistance is due to lower affinity of luminal cells for virus attachment, which can be overcome by pretreating cells—or virus—with neuraminidase. We present an analytical method for quantifying transductional differences between cell types and an optimized protocol for transducing unsorted primary human breast cells in context.« less

  2. Addition of the Neurokinin-1-Receptor Antagonist (RA) Aprepitant to a 5-Hydroxytryptamine-RA and Dexamethasone in the Prophylaxis of Nausea and Vomiting Due to Radiation Therapy With Concomitant Cisplatin

    SciTech Connect (OSTI)

    Jahn, Franziska; Jahn, Patrick; Sieker, Frank; Vordermark, Dirk; Jordan, Karin

    2015-08-01

    Purpose: To assess, in a prospective, observational study, the safety and efficacy of the addition of the neurokinin-1-receptor antagonist (NK1-RA) aprepitant to concomitant radiochemotherapy, for the prophylaxis of radiation therapy–induced nausea and vomiting. Patients and Methods: This prospective observational study compared the antiemetic efficacy of an NK1-RA (aprepitant), a 5-hydroxytryptamine-RA, and dexamethasone (aprepitant regimen) versus a 5-hydroxytryptamine-RA and dexamethasone (control regimen) in patients receiving concomitant radiochemotherapy with cisplatin at the Department of Radiation Oncology, University Hospital Halle (Saale), Germany. The primary endpoint was complete response in the overall phase, defined as no vomiting and no use of rescue therapy in this period. Results: Fifty-nine patients treated with concomitant radiochemotherapy with cisplatin were included in this study. Thirty-one patients received the aprepitant regimen and 29 the control regimen. The overall complete response rates for cycles 1 and 2 were 75.9% and 64.5% for the aprepitant group and 60.7% and 54.2% for the control group, respectively. Although a 15.2% absolute difference was reached in cycle 1, a statistical significance was not detected (P=.22). Furthermore maximum nausea was 1.58 ± 1.91 in the control group and 0.73 ± 1.79 in the aprepitant group (P=.084); for the head-and-neck subset, 2.23 ± 2.13 in the control group and 0.64 ± 1.77 in the aprepitant group, respectively (P=.03). Conclusion: This is the first study of an NK1-RA–containing antiemetic prophylaxis regimen in patients receiving concomitant radiochemotherapy. Although the primary endpoint was not obtained, the absolute difference of 10% in efficacy was reached, which is defined as clinically meaningful for patients by international guidelines groups. Randomized phase 3 studies are necessary to further define the potential role of an NK1-RA in this setting.

  3. Hubble space telescope observations of the afterglow, supernova, and host galaxy associated with the extremely bright GRB 130427A

    SciTech Connect (OSTI)

    Levan, A. J. [Department of Physics, University of Warwick, Coventry, CV4 7AL (United Kingdom); Tanvir, N. R.; Wiersema, K. [Department of Physics and Astronomy, University of Leicester, University Road, Leicester, LE1 7RH (United Kingdom); Fruchter, A. S.; Hounsell, R. A.; Graham, J. [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Hjorth, J.; Fynbo, J. P. U. [Dark Cosmology Centre, Niels Bohr Institute, University of Copenhagen, Juliane Maries Vej 30, DK-2100 Copenhagen (Denmark); Pian, E. [INAF, Trieste Astronomical Observatory, via G.B. Tiepolo 11, I-34143 Trieste (Italy); Mazzali, P. [Astrophysics Research Institute, Liverpool John Moores University, IC2 Liverpool Science Park 146 Brownlow Hill, Liverpool L3 5RF (United Kingdom); Perley, D. A. [Department of Astronomy, California Institute of Technology, MC 249-17, 1200 East California Blvd., Pasadena, CA 91125 (United States); Cano, Z. [Centre for Astrophysics and Cosmology, Science Institute, University of Iceland, Dunhagi 5, 107 Reykjavik (Iceland); Cenko, S. B. [Astrophysics Science Division, NASA Goddard Space Flight Center, Mail Code 661, Greenbelt, MD 20771 (United States); Kouveliotou, C. [Science and Technology Office, ZP12, NASA/Marshall Space Flight Center, Huntsville, AL 35812 (United States); Pe'er, A. [Department of Physics, University College Cork, Cork (Ireland); Misra, K., E-mail: a.j.levan@warwick.ac.uk [Aryabhatta Research Institute of Observational Sciences, Manora Peak, Nainital-263 002 (India)

    2014-09-10

    We present Hubble Space Telescope (HST) observations of the exceptionally bright and luminous Swift gamma-ray burst (GRB), GRB 130427A. At z = 0.34, this burst affords an excellent opportunity to study the supernova (SN) and host galaxy associated with an intrinsically extremely luminous burst (E {sub iso} > 10{sup 54} erg): more luminous than any previous GRB with a spectroscopically associated SN. We use the combination of the image quality, UV capability, and invariant point-spread function of HST to provide the best possible separation of the afterglow, host, and SN contributions to the observed light ?17 rest-frame days after the burst, utilizing a host subtraction spectrum obtained one year later. Advanced Camera for Surveys grism observations show that the associated SN, SN 2013cq, has an overall spectral shape and luminosity similar to SN 1998bw (with a photospheric velocity, v {sub ph} ? 15, 000 km s{sup 1}). The positions of the bluer features are better matched by the higher velocity SN 2010bh (v {sub ph} ? 30, 000 km s{sup 1}), but this SN is significantly fainter and fails to reproduce the overall spectral shape, perhaps indicative of velocity structure in the ejecta. We find that the burst originated ?4 kpc from the nucleus of a moderately star forming (1 M {sub ?} yr{sup 1}), possibly interacting disk galaxy. The absolute magnitude, physical size, and morphology of this galaxy, as well as the location of the GRB within it, are also strikingly similar to those of GRB 980425/SN 1998bw. The similarity of the SNe and environment from both the most luminous and least luminous GRBs suggests that broadly similar progenitor stars can create GRBs across six orders of magnitude in isotropic energy.

  4. A dark energy camera search for missing supergiants in the LMC after the advanced LIGO gravitational-wave event GW150914

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Annis, J.

    2016-05-27

    The collapse of a stellar core is expected to produce gravitational waves (GWs), neutrinos, and in most cases a luminous supernova. Sometimes, however, the optical event could be significantly less luminous than a supernova and a direct collapse to a black hole, where the star just disappears, is possible. The GW event GW150914 was detected by the LIGO Virgo Collaboration via a burst analysis that gave localization contours enclosing the Large Magellanic Cloud (LMC). Shortly thereafter, we used DECam to observe 102 deg2 of the localization area, including 38 deg2 on the LMC for a missing supergiant search. We constructmore » a complete catalog of LMC luminous red supergiants, the best candidates to undergo invisible core collapse, and collected catalogs of other candidates: less luminous red supergiants, yellow supergiants, blue supergiants, luminous blue variable stars, and Wolf–Rayet stars. Of the objects in the imaging region, all are recovered in the images. The timescale for stellar disappearance is set by the free-fall time, which is a function of the stellar radius. Our observations at 4 and 13 days after the event result in a search sensitive to objects of up to about 200 solar radii. We conclude that it is unlikely that GW150914 was caused by the core collapse of a relatively compact supergiant in the LMC, consistent with the LIGO Collaboration analyses of the gravitational waveform as best interpreted as a high mass binary black hole merger. Lastly, we discuss how to generalize this search for future very nearby core-collapse candidates.« less

  5. Double-Blind, Placebo-Controlled Pilot Study of Processed Ultra Emu Oil Versus Placebo in the Prevention of Radiation Dermatitis

    SciTech Connect (OSTI)

    Rollmann, Denise C.; Novotny, Paul J.; Petersen, Ivy A.; Garces, Yolanda I.; Bauer, Heather J.; Yan, Elizabeth S.; Wahner-Roedler, Dietlind; Vincent, Ann; Sloan, Jeff A.; Issa Laack, Nadia N.

    2015-07-01

    Purpose: The purpose of this single-institution pilot study was to evaluate the feasibility and safety of an oil-based skin agent, Ultra Emu Oil, on skin-related toxicity in patients undergoing radiation therapy to the breast or chest wall. Methods and Materials: Patients were randomized 2:1 in a double-blind fashion and were instructed to apply processed Ultra Emu Oil or placebo (cottonseed oil) twice daily during the course of radiation therapy. The oils were applied before the third fraction and continued for 6 weeks after completion of treatment. The primary endpoint was the area under the curve (AUC) of Skindex-16 scale scores over time. Secondary outcomes included maximum grade of radiation dermatitis using the Common Terminology Criteria (CTC) for Adverse Events (CTCAE 3.0), the Skin Toxicity Assessment Tool, quality of life (QOL) measured by Linear Analogue Self-Assessment, and a symptom experience diary (SED). Results: In all, 42 of 45 patients completed the study and were evaluable. The median times to peak rash, skin redness, peeling, and skin swelling were weeks 6, 6, 7, and 7, respectively as measured by the SED. The Skindex AUC scores tended to be lower in emu oil patients than in placebo patients (mean total AUC 7.2 vs 10.4, respectively). This trend was also seen in all the Skindex subdomains. The overall QOL was slightly better in the emu oil group but remained stable throughout the study for both arms. Peak CTC toxicity occurred at week 6. Patients using emu oil appeared slightly worse on maximum CTC grade, but the difference was not significant. Conclusions: This pilot study confirmed the safety of oil-based skin treatments during radiation therapy and suggests a trend for reduced skin toxicity for patients receiving emu oil. A larger study is needed to evaluate the efficacy of emu oil in reducing radiation dermatitis in patients receiving breast radiation.

  6. High Efficancy Integrated Under-Cabinet Phosphorescent OLED

    SciTech Connect (OSTI)

    Michael Hack

    2001-10-31

    In this two year program Universal Display Corporation (UDC) together with the University of Michigan, Teknokon, developed and delivered an energy efficient phosphorescent OLED under cabinet illumination system. Specifically the UDC team goal was in 2011 to deliver five (5) Beta level OLED under cabinet lighting fixtures each consisting of five 6-inch x 6-inch OLED lighting panels, delivering over 420 lumens, at an overall system efficacy of >60 lm/W, a CRI of >85, and a projected lifetime to 70% of initial luminance to exceed 20,000 hours. During the course of this program, the Team pursued the commercialization of these OLED based under cabinet lighting fixtures, to enable the launch of commercial OLED lighting products. The UDC team was ideally suited to develop these novel and efficient solid state lighting fixtures, having both the technical experience and commercial distribution mechanisms to leverage work performed under this contract. UDC's business strategy is to non-exclusively license its PHOLED technology to lighting manufacturers, and also supply them with our proprietary PHOLED materials. UDC is currently working with several licensees who are manufacturing OLED lighting panels using our technology. During this 2 year program, we further developed our high efficiency white Phosphorescent OLEDs from the first milestone, achieving a 80 lm/W single pixel to the final milestone, achieving an under-cabinet PHOLED lighting system that operates at 56 lm/W at 420 lumens. Each luminaire was comprised of ten 15cm x 7.5cm lighting modules mounted in outcoupling enhancement lenses and a control module. The lamps modules are connected together using either plugs or wires with plugs on each end, allowing for unlimited configurations. The lamps are driven by an OLED driver mounted in an enclosure which includes the AC plug. As a result of advancements gained under this program, the path to move OLED lighting panels from development into manufacturing has been

  7. Effect of MLC leaf position, collimator rotation angle, and gantry rotation angle errors on intensity-modulated radiotherapy plans for nasopharyngeal carcinoma

    SciTech Connect (OSTI)

    Bai, Sen; Li, Guangjun; Wang, Maojie; Jiang, Qinfeng; Zhang, Yingjie; Wei, Yuquan

    2013-07-01

    The purpose of this study was to investigate the effect of multileaf collimator (MLC) leaf position, collimator rotation angle, and accelerator gantry rotation angle errors on intensity-modulated radiotherapy plans for nasopharyngeal carcinoma. To compare dosimetric differences between the simulating plans and the clinical plans with evaluation parameters, 6 patients with nasopharyngeal carcinoma were selected for simulation of systematic and random MLC leaf position errors, collimator rotation angle errors, and accelerator gantry rotation angle errors. There was a high sensitivity to dose distribution for systematic MLC leaf position errors in response to field size. When the systematic MLC position errors were 0.5, 1, and 2 mm, respectively, the maximum values of the mean dose deviation, observed in parotid glands, were 4.63%, 8.69%, and 18.32%, respectively. The dosimetric effect was comparatively small for systematic MLC shift errors. For random MLC errors up to 2 mm and collimator and gantry rotation angle errors up to 0.5°, the dosimetric effect was negligible. We suggest that quality control be regularly conducted for MLC leaves, so as to ensure that systematic MLC leaf position errors are within 0.5 mm. Because the dosimetric effect of 0.5° collimator and gantry rotation angle errors is negligible, it can be concluded that setting a proper threshold for allowed errors of collimator and gantry rotation angle may increase treatment efficacy and reduce treatment time.

  8. Cine EPID evaluation of two non-commercial techniques for DIBH

    SciTech Connect (OSTI)

    Jensen, Christopher; Urribarri, Jaime; Cail, Daniel; Rottmann, Joerg; Mishra, Pankaj; Lingos, Tatiana; Niedermayr, Thomas; Berbeco, Ross, E-mail: rberbeco@lroc.harvard.edu [Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115 (United States)] [Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115 (United States)

    2014-02-15

    Purpose: To evaluate the efficacy of two noncommercial techniques for deep inspiration breathhold (DIBH) treatment of left-sided breast cancer (LSBC) usingcine electronic portal imaging device (EPID) images. Methods: 23?875 EPID images of 65 patients treated for LSBC at two different cancer treatment centers were retrieved. At the Milford Regional Cancer Center, DIBH stability was maintained by visual alignment of inroom lasers and patient skin tattoos (TAT). At the South Shore Hospital, a distance-measuring laser device (RTSSD) was implemented. For both centers,cine EPID images were acquired at least once per week during beam-on. Chest wall position relative to image boundary was measured and tracked over the course of treatment for every patient and treatment fraction for which data were acquired. Results: Median intrabeam chest motion was 0.31 mm for the TAT method and 0.37 mm for the RTSSD method. The maximum excursions exceeded our treatment protocol threshold of 3 mm in 0.3% of cases (TAT) and 1.2% of cases (RTSSD). The authors did not observe a clinically significant difference between the two datasets. Conclusions: Both noncommercial techniques for monitoring the DIBH location provided DIBH stability within the predetermined treatment protocol parameters (<3 mm). The intreatment imaging offered by the EPID operating incine mode facilitates retrospective analysis and validation of both techniques.

  9. Generation and pointing stabilization of multi-GeV electron beams from a laser plasma accelerator driven in a pre-formed plasma waveguide

    SciTech Connect (OSTI)

    Gonsalves, A. J.; Nakamura, K.; Daniels, J.; Mao, H.-S.; Benedetti, C.; Schroeder, C. B.; Tóth, Cs.; Tilborg, J. van; Vay, J.-L.; Geddes, C. G. R.; Esarey, E.; Mittelberger, D. E.; Bulanov, S. S.; Leemans, W. P.

    2015-05-15

    Laser pulses with peak power 0.3 PW were used to generate electron beams with energy >4 GeV within a 9 cm-long capillary discharge waveguide operated with a plasma density of ≈7×10{sup 17} cm{sup −3}. Simulations showed that the super-Gaussian near-field laser profile that is typical of high-power femtosecond laser systems reduces the efficacy of guiding in parabolic plasma channels compared with the Gaussian laser pulses that are typically simulated. In the experiments, this was mitigated by increasing the plasma density and hence the contribution of self-guiding. This allowed for the generation of multi-GeV electron beams, but these had angular fluctuation ≳2 mrad rms. Mitigation of capillary damage and more accurate alignment allowed for stable beams to be produced with energy 2.7±0.1 GeV. The pointing fluctuation was 0.6 mrad rms, which was less than the beam divergence of ≲1 mrad full-width-half-maximum.

  10. POLYETHERSULFONE COATING FOR MITIGATING CORROSION OF STEEL IN GEOTHERMAL ENVIRONMENT.

    SciTech Connect (OSTI)

    SUGAMA, T.

    2005-06-01

    Emphasis was directed toward evaluating the usefulness of a polyethersulfone (PES)-dissolved N-methyl pyrrolidone (NMP) solvent precursor as a low-temperature film-forming anti-corrosion coating for carbon steel in simulated geothermal environments at brine temperatures up to 300 C. A {approx} 75 {micro}m thick PES coating performed well in protecting the steel against corrosion in brine at 200 C. However, at {>=} 250 C, the PES underwent severe hydrothermal oxidation that caused the cleavage of sulfone- and ether-linkages, and the opening of phenyl rings. These, in turn, led to sulfone {yields} benzosulfonic acid and ether {yields} benzophenol-type oxidation derivative transformations, and the formation of carbonyl-attached open rings, thereby resulting in the incorporation of the functional groups, hydroxyl and carbonyl, into the coating. The presence of these functional groups raised concerns about the diminutions in water-shedding and water-repellent properties that are important properties of the anti-corrosion coatings; such changes were reflected in an enhancement of the magnitude of susceptibility of the coatings surfaces to moisture. Consequently, the disintegration of the PES structure by hydrothermal oxidation was detrimental to the maximum efficacy of the coating in protecting the steel against corrosion, allowing the corrosive electrolytes to infiltrate easily through it.

  11. Research Highlights 2009-2010 | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    with Efficacy of 82 lmW OSRAM SYLVANIA researchers have demonstrated a downlight luminaire that achieves 1,439 lumens at an efficacy of 82 lmW in steady-state operation. ...

  12. Clone Bacterial Thermal Stable Enzymes in T. Reesei: Cooperative Research and Development Final Report, CRADA Number CRD-01-00105

    SciTech Connect (OSTI)

    Himmel, M. E.

    2010-08-01

    The focus of this CRADA was on improving the efficacy of GCI's primary host for commercial cellulase production, Trichoderma reesei.

  13. Determination and application of bidirectional solar-optical properties of fenestration systems

    SciTech Connect (OSTI)

    Papamichael, K.; Klems, J.; Selkowitz, S.

    1988-03-01

    Accurate determination of the luminous and thermal performance of fenestration systems that incorporate optically complex components requires detailed knowledge of their radiant behavior. We describe a large scanning radiometer used to measure the bidirectional transmittance and reflectance of fenestration systems and components. We present examples of measured data obtained for simple non-specular samples. We describe a method of obtaining the overall properties of fenestration systems by calculation from scanning radiometer measurements of fenestration components. Finally, we describe the application of bidirectional solar-optical properties of fenestration systems to determine their luminous and thermal performance with respect to building energy consumption and occupants' comfort. We also discuss the advantages and limitations of the method, which appears to be promising.

  14. Discomfort Glare: What Do We Actually Know?

    SciTech Connect (OSTI)

    Clear, Robert

    2012-02-29

    Glare models were reviewed with an eye for missing conditions or inconsistencies. We found ambiguities as to when to use small source versus large source models, and as to what constitutes a glare source in a complex scene. We also found surprisingly little information validating the assumed independence of the factors driving glare. A barrier to progress in glare research is the lack of a standardized dependent measure of glare. We inverted the glare models to predict luminance, and compared model predictions against the 1949 Luckiesh & Guth data that form the basis of many of them. The models perform surprisingly poorly, particularly with regards to the luminance-size relationship and additivity. Evaluating glare in complex scenes may require fundamental changes to form of the glare models.

  15. Multichannel optical sensing device

    DOE Patents [OSTI]

    Selkowitz, S.E.

    1985-08-16

    A multichannel optical sensing device is disclosed, for measuring the outdoor sky luminance or illuminance or the luminance or illuminance distribution in a room, comprising a plurality of light receptors, an optical shutter matrix including a plurality of liquid crystal optical shutter elements operable by electrical control signals between light transmitting and light stopping conditions, fiber optical elements connected between the receptors and the shutter elements, a microprocessor based programmable control unit for selectively supplying control signals to the optical shutter elements in a programmable sequence, a photodetector including an optical integrating spherical chamber having an input port for receiving the light from the shutter matrix and at least one detector element in the spherical chamber for producing output signals corresponding to the light, and output units for utilizing the output signals including a storage unit having a control connection to the microprocessor based programmable control unit for storing the output signals under the sequence control of the programmable control unit.

  16. Multichannel optical sensing device

    DOE Patents [OSTI]

    Selkowitz, Stephen E.

    1990-01-01

    A multichannel optical sensing device is disclosed, for measuring the outr sky luminance or illuminance or the luminance or illuminance distribution in a room, comprising a plurality of light receptors, an optical shutter matrix including a plurality of liquid crystal optical shutter elements operable by electrical control signals between light transmitting and light stopping conditions, fiber optic elements connected between the receptors and the shutter elements, a microprocessor based programmable control unit for selectively supplying control signals to the optical shutter elements in a programmable sequence, a photodetector including an optical integrating spherical chamber having an input port for receiving the light from the shutter matrix and at least one detector element in the spherical chamber for producing output signals corresponding to the light, and output units for utilizing the output signals including a storage unit having a control connection to the microprocessor based programmable control unit for storing the output signals under the sequence control of the programmable control unit.

  17. SU-E-J-262: Segmentation in Therapy: Impact of Display

    SciTech Connect (OSTI)

    Sensakovic, W; Letter, H; Pearson, E

    2014-06-01

    Purpose: To determine the calibration of monitors used for structure delineation in radiotherapy and to investigate the impact of window/level on the delineations. Method and Materials: hotometers were used to measure ambient light and luminance for 12 monitors used for delineating structures in radiotherapy. Luminance was determined using AAPM TG-18 patterns TG18-LN12-01 to TG18-LN12-18. The DICOM grayscale display function (GSDF) was calculated for each monitor. To investigate the impact of window and level eight observers each outlined two sets of structures (four structures per set) on CT simulation images. In the first set window and level were initialized at random values and the observers adjusted as needed. In the second set window and level were locked at preselected values for all observers. Results: Ambient light variability at different displays was 24% and was higher than radiology reading rooms. Monitor luminance curves were substantially different than the corresponding GSDF. Monitors demonstrated higher contrast than the GSDF in the lower third of driving levels and lower contrast in the upper third of driving levels. Increased contrast at low driving levels may be to compensate for high ambient light which would otherwise reduce contrast. Abrupt changes in luminance and loss of all contrast at both upper and lower driving levels was observed. Interobserver variability was 379HU for window and 217HU for level. Outline variability was lower when the window and level settings were similar and when they were preselected. Structures without sharp boundaries (e.g., partial volume and a wide window value) resulted in substantial interobserver variability even when window/level were preselected. Conclusion: Substantial variation in monitor calibration and ambient light exists in radiotherapy. Further, the substantially different window/level contributes to outline variability. Future work will quantify the contributions of monitor calibration and window

  18. Consumer Light Bulb Changes: Briefing and Resources for Media and Retailers

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Briefing for Media and Retailers - Lighting eere.energy.gov 1 Consumer Light Bulb Changes: Briefing and Resources for Media and Retailers Briefing for Media and Retailers - Lighting eere.energy.gov 2 * Briefing: - To schedule interviews, please contact DOE Public Affairs at 202-586-4940 * Terms: - Lumens: Commonly a measure of brightness (technically "luminous flux") - CFL: Compact Fluorescent Lamp: The curly fluorescent bulbs - LED: Light Emitting Diode: more recently emerging

  19. ELECTROLUMINESCENT MATERIAL FOR FLAT PANEL DISPLAY

    SciTech Connect (OSTI)

    Smith, D.B.

    2000-11-13

    The purpose of this Cooperative Research and Development Agreement (CRADA) was to develop a new-generation electroluminescent (EL) material for flat panel displays and related applications by using unique and complementary research capabilities at Oak Ridge National Laboratory and OSRAM Sylvania, Inc. The goal was to produce an EL material with a luminance 10 times greater than conventional EL phosphors. An EL material with this increased luminance would have immediate applications for flat panel display devices (e.g., backlighting for liquid-crystal diodes) and for EL lamp technology. OSRAM Sylvania proposed that increased EL phosphor luminance could be obtained by creating composite EL materials capable of alignment under an applied electric field and capable of concentrating the applied electric field. Oak Ridge National Laboratory used pulsed laser deposition as a method for making these composite EL materials. The materials were evaluated for electroluminescence at laboratory facilities at OSRAM Sylvania, Inc. Many composite structures were thus made and evaluated, and it was observed that a composite structure based on alternating layers of a ferroelectric and a phosphor yielded electroluminescence. An enabling step that was not initially proposed but was conceived during the cooperative effort was found to be crucial to the success of the composite structure. The CRADA period expired before we were able to make quantitative measurements of the luminance and efficiency of the composite EL material. Future cooperative work, outside the scope of the CRADA, will focus on making these measurements and will result in the production of a prototype composite EL device.

  20. Galaxies in x-ray selected clusters and groups in Dark Energy Survey data. I. Stellar mass growth of bright central galaxies since z ~ 1.2

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Zhang, Y.; Miller, C.; McKay, T.; Rooney, P.; Evrard, A. E.; Romer, A. K.; R. Perfecto; Song, J.; Desai, S.; Mohr, J.; et al

    2016-01-14

    Here, using the science verification data of the Dark Energy Survey for a new sample of 106 X-ray selected clusters and groups, we study the stellar mass growth of bright central galaxies (BCGs) since redshift z ~ 1.2. Compared with the expectation in a semi-analytical model applied to the Millennium Simulation, the observed BCGs become under-massive/under-luminous with decreasing redshift.

  1. The role of galaxy interaction in the SFR-M {sub *} relation: characterizing morphological properties of Herschel-selected galaxies at 0.2 < z < 1.5

    SciTech Connect (OSTI)

    Hung, Chao-Ling; Sanders, D. B.; Casey, C. M.; Lee, N.; Barnes, J. E.; Koss, M.; Larson, K. L.; Lockhart, K.; Man, A. W. S.; Mann, A. W.; Capak, P.; Kartaltepe, J. S.; Le Floc'h, E.; Riguccini, L.; Scoville, N.; Symeonidis, M.

    2013-12-01

    Galaxy interactions/mergers have been shown to dominate the population of IR-luminous galaxies (L {sub IR} ≳ 10{sup 11.6} L {sub ☉}) in the local universe (z ≲ 0.25). Recent studies based on the relation between galaxies' star formation rates and stellar mass (the SFR-M {sub *} relation or the {sup g}alaxy main sequence{sup )} have suggested that galaxy interaction/mergers may only become significant when galaxies fall well above the galaxy main sequence. Since the typical SFR at a given M {sub *} increases with redshift, the existence of the galaxy main sequence implies that massive, IR-luminous galaxies at high z may not necessarily be driven by galaxy interactions. We examine the role of galaxy interactions in the SFR-M {sub *} relation by carrying out a morphological analysis of 2084 Herschel-selected galaxies at 0.2 < z < 1.5 in the COSMOS field. Using a detailed visual classification scheme, we show that the fraction of 'disk galaxies' decreases and the fraction of 'irregular' galaxies increases systematically with increasing L {sub IR} out to z ≲ 1.5 and z ≲ 1.0, respectively. At L {sub IR} >10{sup 11.5} L {sub ☉}, ≳ 50% of the objects show evident features of strongly interacting/merger systems, where this percentage is similar to the studies of local IR-luminous galaxies. The fraction of interacting/merger systems also systematically increases with the deviation from the SFR-M {sub *} relation, supporting the view that galaxies falling above the main sequence are more dominated by mergers than the main-sequence galaxies. Meanwhile, we find that ≳ 18% of massive IR-luminous 'main-sequence galaxies' are classified as interacting systems, where this population may not evolve through the evolutionary track predicted by a simple gas exhaustion model.

  2. Achieving Record Efficiency for Blue OLEDs by Controlling the Charge Balance

    Broader source: Energy.gov [DOE]

    Researchers at the University of Florida (UF) have demonstrated a blue phosphorescent organic light-emitting diode (OLED) with a peak power efficiency of 50 lm/W and an external quantum efficiency exceeding 20 percent at a luminance of 1,000 cd/m2, using no external light extraction techniques. This accomplishment is believed to be the world record in blue OLED efficiency.

  3. THE AROMATIC FEATURES IN VERY FAINT DWARF GALAXIES

    SciTech Connect (OSTI)

    Wu Ronin; Hogg, David W.; Moustakas, John

    2011-04-01

    We present optical and mid-infrared photometry of a statistically complete sample of 29 dwarf galaxies (M{sub r} > - 15 mag) selected from the Sloan Digital Sky Survey (SDSS) spectroscopic sample and observed in the mid-infrared with Spitzer IRAC. This sample contains nearby (redshift {approx}<0.005) galaxies 3 mag fainter than previously studied samples. We compare our sample with other star-forming galaxies that have been observed with both IRAC and SDSS. We examine the relationship of the infrared color, [3.6]-[7.8], sensitive to polycyclic aromatic hydrocarbon (PAH) abundance and also hot dust and stellar continuum, with star formation rates (SFRs), oxygen abundances, and radiation hardness, all estimated by optical emission lines. Consistent with studies of more luminous dwarfs, we find that these dwarf galaxies show much redder [3.6]-[7.8] color than luminous galaxies with similar specific SFRs. Unlike luminous galaxies, we find that these dwarf galaxies show no significant dependence at all of the [3.6]-[7.8] color on SFR, oxygen abundance, or radiation hardness, despite the fact that the sample spans a significant range in all of these quantities. When the dwarfs in our sample are compared with more luminous dwarfs, we find that the [3.6]-[7.8] color, potentially tracing the PAH emission, depends on oxygen abundance and radiation hardness. However, these two parameters are correlated with one another as well; we break this degeneracy by looking at the PAH-oxygen abundance relation at a fixed radiation hardness and the PAH-hardness relation at a fixed oxygen abundance. This test shows that the [3.6]-[7.8] color in dwarf galaxies appears to depend more directly on oxygen abundance based on the data currently available.

  4. Organic light emitting device structure for obtaining chromaticity stability

    DOE Patents [OSTI]

    Tung, Yeh-Jiun; Ngo, Tan

    2007-05-01

    The present invention relates to organic light emitting devices (OLEDs). The devices of the present invention are efficient white or multicolored phosphorescent OLEDs which have a high color stability over a wide range of luminances. The devices of the present invention comprise an emissive region having at least two emissive layers, with each emissive layer comprising a different host and emissive dopant, wherein at least one of the emissive dopants emits by phosphorescence.

  5. Organic light emitting device structures for obtaining chromaticity stability

    DOE Patents [OSTI]

    Tung, Yeh-Jiun; Lu, Michael; Kwong, Raymond C.

    2005-04-26

    The present invention relates to organic light emitting devices (OLEDs). The devices of the present invention are efficient white or multicolored phosphorescent OLEDs which have a high color stability over a wide range of luminances. The devices of the present invention comprise an emissive region having at least two emissive layers, with each emissive layer comprising a different host and emissive dopant, wherein at least one of the emissive dopants emits by phosphorescence.

  6. QUARTERLY NUCLEAR POWER DEPLOYMENT SUMMARY JANUARY 2014

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    4 Updates available at: www.energy.gov/ne NEXT UPDATE - April 2014 Page 1 News Updates  Luminant has requested a suspension of the NRC's review of its Comanche Peak Combined Construction and Operating License (COL) application. The company cited impacts to the review schedule of the Mitsubishi Heavy Industries US Advanced Pressurized Water Reactor (US- APWR) due to the vendor's desire to refocus its resources to reactor restarts in Japan as well as low electricity prices driven by low natural

  7. Structure, Inhibition and Regulation of Two-pore Channel TPC1 from

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Arabidopsis thaliana | Stanford Synchrotron Radiation Lightsource Structure, Inhibition and Regulation of Two-pore Channel TPC1 from Arabidopsis thaliana Thursday, March 31, 2016 Figure Overview of the TPC1 Structure. a, Top view from the luminal side onto the membrane plane and b, side view from the right side with the perpendicular to the membrane plane vertical of the TPC1 structure labeled by domain and transmembrane helices. Dashes denote approximate endolysosomal, membrane, and

  8. Understanding Flicker | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Research & Development » Technology Application R&D » Understanding Flicker Understanding Flicker All conventional light sources modulate luminous flux and intensity to some degree, usually as a consequence of drawing power from AC mains sources. Many terms are used when referring to this time variation, including "flicker," "flutter," and "shimmer." The Illuminating Engineering Society of North America (IES) Lighting Handbook defines flicker as "the

  9. The Water Maser in II Zw 96: Scientific Justification

    SciTech Connect (OSTI)

    Wiggins, Brandon Kerry

    2015-08-06

    We propose a VLBI search to image and locate the water emission in II Zw 96. We propose 3 sites within II Zw 96 for VLBI followup (see the proposed target listing below). We request 2.5 hours of on-source integration time with the VLBA per source. The array will achieve ~ 65µJy sensitivity in K band in this time which will be sufficient to detect luminous water maser features.

  10. 200 N. Spring Street

    Office of Legacy Management (LM)

    Dipartment of Energy. ,' Washington,DC20585 ., .\ FEB 1 7 ' 19g5' ,The Honorable Richa,rd. Riordon .', 200 N. Spring Street 'Los Angeles, California ,90012 '~ Dear Mayor Riordon: " Secretary of Energy Hazel O'Leary'has announced a neb approach to openness ins- the Department of Energy (DOE) and its communications with the public. fin support of this initiative, we are pleased~ to forward the enclosed information related to the. former Shannon Luminous Metals site in your jurisdiction that

  11. DOE Challenge Home, Washington Program Requirements

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... documentation of maximum allowable dead load and live load ratings of the roof, ... documentation of maximum allowable dead load and live load ratings of the roof, ...

  12. The United Illuminating Company - ZREC and LREC Long Term Contracts...

    Broader source: Energy.gov (indexed) [DOE]

    Savings Category Solar Photovoltaics Wind (All) Biomass Hydroelectric Landfill Gas Fuel Cells using Renewable Fuels Maximum Rebate Maximum Bid price for Year 3 (2014):...

  13. Property:Incentive/EligSysSize | Open Energy Information

    Open Energy Info (EERE)

    minimum
    Recycled Energy: 15 Megawatt maximum Alameda Municipal Power - Solar Photovoltaics Rebate Program (California) + Maximum size is 1 MW or 110% of customer's...

  14. NREL: Measurements and Characterization - Current Versus Voltage

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of devices, including: open-circuit voltage (Voc), short-circuit current (Isc), fill factor (FF), maximum power output of the device (Pmax), voltage at maximum power...

  15. U.S. Fuel Ethanol Plant Production Capacity

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    Note: In previous ethanol capacity reports, EIA included data on maximum sustainable ... The collection and publication efforts for the maximum sustainable data value were ...

  16. Design, Operation, and Controlled-Island Operation of the U.S...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... for a microgrid are maximum load and maximum generation. ... cost from the National Renewable Energy Laboratory (NREL) at ... and south parts of the site (teams and organizer loads). ...

  17. SMUD - Residential Energy Efficiency Rebate Program | Department...

    Broader source: Energy.gov (indexed) [DOE]

    Insulation Windows Roofs Other EE Reflective Roofs Pool Pumps LED Lighting Maximum Rebate Contact SMUD for individual program or equipment maximum amounts Program Info...

  18. A Baryonic Solution to the Missing Satellites Problem

    SciTech Connect (OSTI)

    Brooks, Alyson M.; Kuhlen, Michael; Zolotov, Adi; Hooper, Dan

    2013-03-01

    It has been demonstrated that the inclusion of baryonic physics can alter the dark matter densities in the centers of low-mass galaxies, making the central dark matter slope more shallow than predicted in pure cold dark matter simulations. This flattening of the dark matter profile can occur in the most luminous subhalos around Milky Way mass galaxies. Zolotov et al. have suggested a correction to be applied to the central masses of dark matter-only satellites in order to mimic the affect of (1) the flattening of the dark matter cusp due to supernova feedback in luminous satellites and (2) enhanced tidal stripping due to the presence of a baryonic disk. In this paper, we apply this correction to the z = 0 subhalo masses from the high resolution, dark matter-only Via Lactea II (VL2) simulation, and find that the number of massive subhalos is dramatically reduced. After adopting a stellar mass to halo mass relationship for the VL2 halos, and identifying subhalos that are (1) likely to be destroyed by stripping and (2) likely to have star formation suppressed by photo-heating, we find that the number of massive, luminous satellites around a Milky Way mass galaxy is in agreement with the number of observed satellites around the Milky Way or M31. We conclude that baryonic processes have the potential to solve the missing satellites problem

  19. Simultaneous Integrated Boost–Intensity Modulated Radiation Therapy With Concomitant Capecitabine and Mitomycin C for Locally Advanced Anal Carcinoma: A Phase 1 Study

    SciTech Connect (OSTI)

    Deenen, Maarten J.; Dewit, Luc; Boot, Henk; Beijnen, Jos H.; Faculty of Science, Department of Pharmaceutical Sciences, Division of Pharmaco-epidemiology and Clinical Pharmacology, Utrecht University, Utrecht ; Schellens, Jan H.M.; Faculty of Science, Department of Pharmaceutical Sciences, Division of Pharmaco-epidemiology and Clinical Pharmacology, Utrecht University, Utrecht ; Cats, Annemieke

    2013-04-01

    Purpose: Newer radiation techniques, and the application of continuous 5-FU exposure during radiation therapy using oral capecitabine may improve the treatment of anal cancer. This phase 1, dose-finding study assessed the feasibility and efficacy of simultaneous integrated boost–intensity modulated radiation therapy (SIB-IMRT) with concomitant capecitabine and mitomycin C in locally advanced anal cancer, including pharmacokinetic and pharmacogenetic analyses. Methods and Materials: Patients with locally advanced anal carcinoma were treated with SIB-IMRT in 33 daily fractions of 1.8 Gy to the primary tumor and macroscopically involved lymph nodes and 33 fractions of 1.5 Gy electively to the bilateral iliac and inguinal lymph node areas. Patients received a sequential radiation boost dose of 3 × 1.8 Gy on macroscopic residual tumor if this was still present in week 5 of treatment. Mitomycin C 10 mg/m{sup 2} (maximum 15 mg) was administered intravenously on day 1, and capecitabine was given orally in a dose-escalated fashion (500-825 mg/m{sup 2} b.i.d.) on irradiation days, until dose-limiting toxicity emerged in ≥2 of maximally 6 patients. An additional 8 patients were treated at the maximum tolerated dose (MTD). Results: A total of 18 patients were included. The MTD of capecitabine was determined to be 825 mg/m{sup 2} b.i.d. The predominant acute grade ≥3 toxicities included radiation dermatitis (50%), fatigue (22%), and pain (6%). Fifteen patients (83% [95%-CI: 66%-101%]) achieved a complete response, and 3 (17%) patients a partial response. With a median follow-up of 28 months, none of the complete responders, and 2 partial responders had relapsed. Conclusions: SIB-IMRT with concomitant single dose mitomycin C and capecitabine 825 mg/m{sup 2} b.i.d. on irradiation days resulted in an acceptable safety profile, and proved to be a tolerable and effective treatment regimen for locally advanced anal cancer.

  20. Changes in mitogen-activated protein kinase in cerebellar granule neurons by polybrominated diphenyl ethers and polychlorinated biphenyls

    SciTech Connect (OSTI)

    Fan Chunyang; Besas, Jonathan

    2010-05-15

    Polybrominated diphenyl ethers (PBDEs) are used as additive flame retardants and have been detected in human blood, adipose tissue, and breast milk. Both in vitro and in vivo studies have shown that the effects of PBDEs are similar to the known human developmental neurotoxicants such as polychlorinated biphenyls (PCBs) on a molar basis. Previously, we reported that PBDE mixtures and congeners, perturbed calcium homeostasis which is critical for the development and function of the nervous system. In the present study, we tested whether environmentally relevant PBDE/PCB mixtures and congeners affected mitogen-activated protein kinase (MAPK) pathways, which are down-stream events of calcium signaling in cerebellar granule neuronal cultures. In this study, phosphorylated extracellular signal-regulated kinase (pERK)1/2, a widely studied MAPK cascade and known to be involved in learning and memory, levels were quantitated using western blot technique with phospho-specific antibodies. Glutamate (a positive control) increased pERK1/2 in a time- and concentration-dependent manner reaching maximum activation at 5-30 min of exposure and at doses >= 10 muM. Both Aroclor 1254 (a commercial penta PCB mixture) and DE-71 (a commercial penta PBDE mixture) elevated phospho-ERK1/2, producing maximum stimulation at 30 min and at concentrations >= 3 mug/ml; Aroclor 1254 was more efficacious than DE-71. DE-79 (an octabrominated diphenyl ether mixture) also elevated phospho-ERK1/2, but to a lesser extent than that of DE-71. PBDE congeners 47, 77, 99, and 153 also increased phospo-ERK1/2 in a concentration-dependent manner. The data indicated that PBDE congeners are more potent than the commercial mixtures. PCB 47 also increased phospho-ERK1/2 like its structural analog PBDE 47, but to a lesser extent, suggesting that these chemicals affect similar pathways. Cytotoxicity, measured as %LDH release, data showed that higher concentrations (> 30 muM) and longer exposures (> 30 min) are