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  1. ,"Detroit, MI Natural Gas Pipeline Imports From Canada (MMcf...

    U.S. Energy Information Administration (EIA) Indexed Site

    ,"Worksheet Name","Description"," Of Series","Frequency","Latest Data for" ,"Data 1","Detroit, MI Natural Gas Pipeline Imports From Canada (MMcf)",1,"Annual",2014 ,"Release...

  2. DOE - Office of Legacy Management -- Dow-Detroit Edison Project - MI 0-02

    Office of Legacy Management (LM)

    Dow-Detroit Edison Project - MI 0-02 FUSRAP Considered Sites Site: Dow-Detroit Edison Project (MI.0-02 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Detroit , Michigan MI.0-02-1 Evaluation Year: 1987 MI.0-02-1 Site Operations: Performed reference design work for a special fast breeder type reactor. MI.0-02-1 Site Disposition: Eliminated - No radioactive material handled at the site MI.0-02-1 Radioactive Materials Handled: No

  3. Detroit Workshop Highlights

    Broader source: Energy.gov [DOE]

    View the video showing highlights from the ninth annual DOE Solid-State Lighting Market Development Workshop in Detroit.

  4. Detroit, Michigan: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    Detroit, Michigan: Energy Resources (Redirected from Detroit, MI) Jump to: navigation, search Equivalent URI DBpedia Coordinates 42.331427, -83.0457538 Show Map Loading map......

  5. American Recovery and Reinvestment Act ( ARRA) FEMP Technical Assistance, U.S. General Services Administration - Project 194 U.S. Custom Cargo Inspection Facility, Detroit, MI

    SciTech Connect (OSTI)

    Arends, J.; Sandusky, William F.

    2010-05-31

    This report documents the findings of an on-site audit of the U.S. Customs Cargo Inspection Facility (CIF) in Detroit, Michigan. The federal landlord for this building is the General Services Administration (GSA). The focus of the audit was to identify various no-cost or low-cost energy-efficiency opportunities that, once implemented, would reduce electrical and gas consumption and increase the operational efficiency of the building. This audit also provided an opportunity to identify potential capital cost projects that should be considered in the future to acquire additional energy (electric and gas) and water savings to further increase the operational efficiency of the building.

  6. City of Detroit- SmartBuildings Detroit Green Fund Loan

    Broader source: Energy.gov [DOE]

    The Economic Development Corporation (EDC) of the City of Detroit is offering financial assistance to commercial, institutional and public buildings in Detroit that install energy efficiency and ...

  7. SEP Success Story: Detroit Diesel

    Broader source: Energy.gov [DOE]

    This video features Detroit Diesel’s success with DOE’s Superior Energy Performance® (SEP™) program. Daimler’s Detroit Diesel Corporation facility earned Platinum SEP certification in November 2015...

  8. Detroit, MI Natural Gas Exports to Canada

    Gasoline and Diesel Fuel Update (EIA)

    2009 2010 2011 2012 2013 2014 View History Pipeline Volumes 21 79 19 0 165 188 1996-2014 Pipeline Prices 4.53 8.37 5.17 -- 4.44 5.26 1996...

  9. Detroit, MI Natural Gas Exports to Canada

    Gasoline and Diesel Fuel Update (EIA)

    275 43,690 50,347 50,439 46,981 37,528 1996-2015 Pipeline Prices 4.69 4.26 3.10 4.04 5.36 2.91

  10. Ricardo Detroit Technical Center | Open Energy Information

    Open Energy Info (EERE)

    Ricardo Detroit Technical Center Jump to: navigation, search Name: Ricardo Detroit Technical Center Place: Van Buren Township, Michigan Zip: 48111-1641 Sector: Services Product:...

  11. Detroit Auto Show 2012 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Detroit Auto Show 2012 Detroit Auto Show 2012 Addthis 1 of 10 Energy Secretary Steven Chu with Chrysler Chief Executive Sergio Marchionne. Image: Hantz Leger (Energy Department ...

  12. TEXT-ALTERNATIVE VERSION: DETROIT WORKSHOP HIGHLIGHTS

    Broader source: Energy.gov [DOE]

    Mayor Mike Duggan, City of Detroit: The DOE has just been an outstanding partner, and I'm really glad to be welcoming you here at this time. So welcome to Detroit.

  13. DOE - Office of Legacy Management -- Wolverine Tube Division - MI 05

    Office of Legacy Management (LM)

    Wolverine Tube Division - MI 05 FUSRAP Considered Sites Site: Wolverine Tube Division (MI.05) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: Wolverine Tube Division of Calumet & Hecla Consolidated Copper Co. Star Tool Hermes Automotive Manufacturing Corporation MI.05-1 MI.05-2 Location: 1411 Central Avenue , Detroit , Michigan MI.05-3 Evaluation Year: 1990 MI.05-2 Site Operations: 1943 - Conducted research and development of methods for spinning

  14. Detroit Commuter Hydrogen Project

    SciTech Connect (OSTI)

    Brooks, Jerry; Prebo, Brendan

    2010-07-31

    This project was undertaken to demonstrate the viability of using hydrogen as a fuel in an internal combustion engine vehicle for use as a part of a mass transit system. The advantages of hydrogen as a fuel include renew-ability, minimal environmental impact on air quality and the environment, and potential to reduce dependence on foreign energy sources for the transportation sector. Recognizing the potential for the hydrogen fuel concept, the Southeast Michigan Congress of Governments (SEMCOG) determined to consider it in the study of a proposed regional mass transit rail system for southeast Michigan. SEMCOG wanted to evaluate the feasibility of using hydrogen fueled internal combustion engine (H2ICE) vehicles in shuttle buses to connect the Detroit Metro Airport to a proposed, nearby rail station. Shuttle buses are in current use on the airport for passenger parking and inter-terminal transport. This duty cycle is well suited to the application of hydrogen fuel at this time because of the ability to re-fuel vehicles at a single nearby facility, overcoming the challenge of restricted fuel availability in the undeveloped hydrogen fuel infrastructure. A cooperative agreement between SEMCOG and the DOE was initiated and two H2ICE buses were placed in regular passenger service on March 29, 2009 and operated for six months in regular passenger service. The buses were developed and built by the Ford Motor Company. Wayne County Airport Authority provided the location for the demonstration with the airport transportation contractor, Metro Cars Inc. operating the buses. The buses were built on Ford E450 chassis and incorporated a modified a 6.8L V-10 engine with specially designed supercharger, fuel rails and injectors among other sophisticated control systems. Up to 30 kg of on-board gaseous hydrogen were stored in a modular six tank, 350 bar (5000 psi) system to provide a 150 mile driving range. The bus chassis and body were configured to carry nine passengers with

  15. DOE - Office of Legacy Management -- Detrex Corp - MI 10

    Office of Legacy Management (LM)

    Detrex Corp - MI 10 FUSRAP Considered Sites Site: Detrex Corp. (MI.10 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Detroit , Michigan MI.10-1 Evaluation Year: 1987 MI.10-2 Site Operations: Conducted experimental runs relative to pickling/degreasing of one handful of uranium turnings MI.10-1 Site Disposition: Eliminated - Potential for contamination considered remote due to small quantity of material handled - There is no

  16. Detroit, Michigan: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    Detroit, Michigan: Energy Resources Jump to: navigation, search Equivalent URI DBpedia Coordinates 42.331427, -83.0457538 Show Map Loading map... "minzoom":false,"mappingservi...

  17. City of Detroit Lakes, Minnesota (Utility Company) | Open Energy...

    Open Energy Info (EERE)

    Lakes, Minnesota (Utility Company) Jump to: navigation, search Name: City of Detroit Lakes Place: Minnesota Website: www.ci.detroit-lakes.mn.usmai Facebook: https:...

  18. City of Detroit (Michigan) EIA Revenue and Sales - February 2008...

    Open Energy Info (EERE)

    City of Detroit (Michigan) EIA Revenue and Sales - February 2008 Jump to: navigation, search EIA Monthly Electric Utility Sales and Revenue Data for City of Detroit for February...

  19. City of Detroit (Michigan) EIA Revenue and Sales - May 2008 ...

    Open Energy Info (EERE)

    Detroit (Michigan) EIA Revenue and Sales - May 2008 Jump to: navigation, search EIA Monthly Electric Utility Sales and Revenue Data for City of Detroit for May 2008. Monthly...

  20. City of Detroit (Michigan) EIA Revenue and Sales - February 2009...

    Open Energy Info (EERE)

    City of Detroit for February 2009. Monthly Electric Utility Sales and Revenue Data Short Name 2009-02 Utility Company City of Detroit (Michigan) Place Michigan Start Date...

  1. City of Detroit (Michigan) EIA Revenue and Sales - November 2008...

    Open Energy Info (EERE)

    City of Detroit (Michigan) EIA Revenue and Sales - November 2008 Jump to: navigation, search EIA Monthly Electric Utility Sales and Revenue Data for City of Detroit for November...

  2. City of Detroit (Michigan) EIA Revenue and Sales - December 2008...

    Open Energy Info (EERE)

    City of Detroit for December 2008. Monthly Electric Utility Sales and Revenue Data Short Name 2008-12 Utility Company City of Detroit (Michigan) Place Michigan Start Date...

  3. PP-221 Detroit Edison Company | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    Permit authorizing Detroit Edison Company to construct, operate and maintain electric transmission facilities at the U.S. - Canada border. PDF icon PP-221 Detroit.pdf More ...

  4. Restoring Detroits Street Lighting System

    Energy Savers [EERE]

    Restoring Detroit's Street Lighting System September 2015 Bruce Kinzey PNNL- 24692 Restoring Detroit's Street Lighting System Bruce Kinzey September 2015 Prepared ...

  5. Secretary Moniz Applauds Detroit's LED Street Lighting Upgrades...

    Broader source: Energy.gov (indexed) [DOE]

    an update of its largely broken public lighting system, speaking at the Detroit Area ... The Detroit street lighting project includes the participation of the Energy Department, ...

  6. DOE - Office of Legacy Management -- Carboloy Co - MI 12

    Office of Legacy Management (LM)

    Carboloy Co - MI 12 FUSRAP Considered Sites Site: Carboloy Co. (MI.12 ) Eliminated from further consideration under FUSRAP - AEC licensed facility Designated Name: Not Designated Alternate Name: General Electric MI.12-1 Location: 11177 E. Eight Mile Road , Detroit , Michigan MI.12-1 MI.12-2 Evaluation Year: 1987-1991 MI.12-3 MI.12-4 MI.12-6 Site Operations: Turned-down the outer diameter of uranium metal slugs and conducted pilot plant scale operations for hot pressing uranium dioxide pellets

  7. Restoring Detroit's Street Lighting System

    SciTech Connect (OSTI)

    Kinzey, Bruce R.

    2015-10-21

    The City of Detroit is undertaking a comprehensive restoration of its street lighting system that includes transitioning the existing high-pressure sodium (HPS) sources to light-emitting diode (LED). Detroit’s well-publicized financial troubles over the last several years have added many hurdles and constraints to this process. Strategies to overcome these issues have largely been successful, but have also brought some mixed results. This document provides an objective review of the circumstances surrounding the system restoration, the processes undertaken and decisions made, and the results so far.

  8. SEP Case Study Webinar: Detroit Diesel Slides

    Broader source: Energy.gov [DOE]

    This page contains the presentation slides from the Superior Energy Performance (SEP) Measurement and Verification Case Study webinar on Detroit Diesel hosted on July 14, 2016. This webinar...

  9. SmartBuildings Detroit Commercial Case Study

    Broader source: Energy.gov [DOE]

    SmartBuildings Detroit Commercial Case Study, a document from BetterBuildings for Michigan posted on the website of the U.S. Department of Energy's Better Buildings Neighborhood Program.

  10. Detroit, MI Natural Gas Imports by Pipeline from Canada

    Gasoline and Diesel Fuel Update (EIA)

    2009 2010 2011 2012 2013 2014 View History Pipeline Volumes 21 79 19 0 165 188 1996-2014 Pipeline Prices 4.53 8.37 5.17 -- 4.44 5.26 1996-2014

  11. City of Detroit (Michigan) EIA Revenue and Sales - June 2008...

    Open Energy Info (EERE)

    City of Detroit for June 2008. Monthly Electric Utility Sales and Revenue Data Short Name 2008-06 Utility Company City of Detroit (Michigan) Place Michigan Start Date 2008-06-01...

  12. City of Detroit (Michigan) EIA Revenue and Sales - August 2008...

    Open Energy Info (EERE)

    City of Detroit for August 2008. Monthly Electric Utility Sales and Revenue Data Short Name 2008-08 Utility Company City of Detroit (Michigan) Place Michigan Start Date 2008-08-01...

  13. A Look Inside the Detroit Auto Show | Department of Energy

    Energy Savers [EERE]

    the Detroit Auto Show A Look Inside the Detroit Auto Show January 12, 2011 - 1:15pm Addthis Kerry Duggan Kerry Duggan Waking up at 4:30AM is not my idea of fun. But after I ...

  14. DOE - Office of Legacy Management -- Revere Copper and Brass Co - MI 04

    Office of Legacy Management (LM)

    Revere Copper and Brass Co - MI 04 FUSRAP Considered Sites Site: REVERE COPPER AND BRASS CO. ( MI.04 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: Revere Copper and Brass MI.04-1 Location: 5851 West Jefferson Street , Detroit , Michigan MI.04-1 Evaluation Year: 1990 MI.04-2 Site Operations: Extrusion of tuballoy rods, myrnalloy rods and beryllium shapes in the 1940s. MI.04-3 MI.04-4 Site Disposition: Eliminated - Radiation levels below criteria

  15. Detroit Beach, Michigan: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    Detroit Beach, Michigan: Energy Resources Jump to: navigation, search Equivalent URI DBpedia Coordinates 41.9311563, -83.3268753 Show Map Loading map... "minzoom":false,"mappi...

  16. City of Detroit (Michigan) EIA Revenue and Sales - January 2009...

    Open Energy Info (EERE)

    January 2009 Jump to: navigation, search EIA Monthly Electric Utility Sales and Revenue Data for City of Detroit for January 2009. Monthly Electric Utility Sales and Revenue Data...

  17. City of Detroit (Michigan) EIA Revenue and Sales - January 2008...

    Open Energy Info (EERE)

    January 2008 Jump to: navigation, search EIA Monthly Electric Utility Sales and Revenue Data for City of Detroit for January 2008. Monthly Electric Utility Sales and Revenue Data...

  18. Detroit Edison Advanced Implementation of Energy Storage Technologies

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of Energy Storage Technologies Project Description Detroit Edison will complete installation and begin an aggregated 1 MW Community Energy Storage (CES) System in their ...

  19. The Detroit Edison Company Smart Grid Demonstration Project ...

    Open Energy Info (EERE)

    based in Detroit, Michigan. Overview Demonstrate the use and benefits of Community Energy Storage (CES) systems for utilities and test the ability to integrate secondary-use...

  20. 2014 SSL Market Development Workshop Presentations Posted

    Broader source: Energy.gov [DOE]

    More than 175 attendees gathered at the ninth annual DOE Solid-State Lighting Market Development Workshop, held November 12–13 in Detroit, to learn the latest on today's toughest LED lighting...

  1. City of Detroit (Michigan) EIA Revenue and Sales - July 2008...

    Open Energy Info (EERE)

    July 2008 Jump to: navigation, search EIA Monthly Electric Utility Sales and Revenue Data for City of Detroit for July 2008. Monthly Electric Utility Sales and Revenue Data Short...

  2. City of Detroit (Michigan) EIA Revenue and Sales - March 2009...

    Open Energy Info (EERE)

    9 Jump to: navigation, search EIA Monthly Electric Utility Sales and Revenue Data for City of Detroit for March 2009. Monthly Electric Utility Sales and Revenue Data Short Name...

  3. City of Detroit (Michigan) EIA Revenue and Sales - March 2008...

    Open Energy Info (EERE)

    March 2008 Jump to: navigation, search EIA Monthly Electric Utility Sales and Revenue Data for City of Detroit for March 2008. Monthly Electric Utility Sales and Revenue Data Short...

  4. City of Detroit (Michigan) EIA Revenue and Sales - April 2008...

    Open Energy Info (EERE)

    April 2008 Jump to: navigation, search EIA Monthly Electric Utility Sales and Revenue Data for City of Detroit for April 2008. Monthly Electric Utility Sales and Revenue Data Short...

  5. Detroit Edison Co | Open Energy Information

    Open Energy Info (EERE)

    Yes Activity Buying Transmission Yes Activity Distribution Yes Activity Wholesale Marketing Yes Activity Retail Marketing Yes Activity Bundled Services Yes Alt Fuel Vehicle Yes...

  6. Superior Energy Performance Webinar: Detroit Diesel SEP Success, July 14,

    Energy Savers [EERE]

    2PM eastern time | Department of Energy Webinar: Detroit Diesel SEP Success, July 14, 2PM eastern time Superior Energy Performance Webinar: Detroit Diesel SEP Success, July 14, 2PM eastern time July 6, 2016 - 2:13pm Addthis The DOE Advanced Manufacturing Office (AMO) is pleased to announce the fourth webinar in its series highlighting U.S. manufacturing facilities that have achieved Superior Energy Performance (SEP) certification. These facilities have fully implemented the ISO 50001

  7. Health-hazard evaluation report HETA 84-484-1754, Detroit Fire Fighters, Detroit, Michigan

    SciTech Connect (OSTI)

    Anderson, K.E.; Melius, J.M.

    1986-12-01

    In response to a request from the International Association of Fire Fighters on behalf of the Detroit Fire Fighters Association, Detroit, Michigan, a health hazard evaluation was made of respiratory symptoms and skin irritation in fire fighters involved in a large fire and explosion at a warehouse. Over 200 fire fighters from fire-fighting organizations in three communities were involved in the incident. Site runoff water contained chlordane and malathion in low parts per million; other samples were negative. Nose and throat irritation, cough, and shortness of breath were experienced by a large proportion of fire fighters following the fire, and in 14, 15, and 17 percent, respectively, symptoms persisted over 2 months. Symptoms were significantly associated with time spent at the scene and time spent in heavy smoke. Pulmonary function tests were abnormal in 14 cases, ten due to obstructive lung disease, three to restrictive lung disease, and one to a combination. The authors conclude that better protective equipment is needed for fire fighters at chemical fires. Recommendations include development of a hazardous-materials response team, and implementation of a routine medical surveillance program.

  8. Detroit, MI Natural Gas Pipeline Exports to Canada (Million Cubic Feet)

    Gasoline and Diesel Fuel Update (EIA)

    Cubic Feet) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 1990's 2.36 2.55 2.26 2.30 2000's 3.74 4.57 3.03 5.47 6.47 8.12 7.61 6.88 8.37 4.01 2010's 4.69 4.26 3.10 4.04 5.36 2.9 Cubic Feet)

    Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2011 4.72 4.58 4.22 4.51 4.66 4.73 4.55 4.45 4.19 3.92 3.79 3.60 2012 3.14 2.95 2.61 2.33 2.50 2.62 3.08 3.12 2.99 3.41 4.13 3.90 2013 4.04 3.67 3.96 4.42 4.42 4.26 4.02 3.84 3.90 3.89 3.79 4.34 2014 5.67 10.21 7.89

  9. Detroit, MI Natural Gas Pipeline Imports From Canada (Million Cubic Feet)

    Gasoline and Diesel Fuel Update (EIA)

    Cubic Feet) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 1990's 2.75 2.51 2.43 2.51 2000's 3.82 9.34 3.56 5.96 6.27 -- -- 8.28 6.58 4.53 2010's 8.37 5.17 -- 4.4 Cubic Feet)

    Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2011 4.95 5.33 2013 3.80 4.50 4.09 4.63 201

    Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2011 8 11 2013 16 140 24 10 2014

  10. Detroit, MI Natural Gas Pipeline Exports to Canada (Dollars per Thousand

    U.S. Energy Information Administration (EIA) Indexed Site

    Cubic Feet) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 1990's 2.36 2.55 2.26 2.30 2000's 3.74 4.57 3.03 5.47 6.47 8.12 7.61 6.88 8.37 4.01 2010's 4.69 4.26 3.10 4.04 5.36 2.9

  11. Detroit, MI Natural Gas Pipeline Exports to Canada (Dollars per Thousand

    U.S. Energy Information Administration (EIA) Indexed Site

    Cubic Feet) Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2011 4.72 4.58 4.22 4.51 4.66 4.73 4.55 4.45 4.19 3.92 3.79 3.60 2012 3.14 2.95 2.61 2.33 2.50 2.62 3.08 3.12 2.99 3.41 4.13 3.90 2013 4.04 3.67 3.96 4.42 4.42 4.26 4.02 3.84 3.90 3.89 3.79 4.34 2014 5.67 10.21 7.89 4.89 4.93 4.86 4.44 4.06 4.14 4.11 4.20 4.16 2015 3.38 3.80 3.19 2.77 2.78 2.94 2.97 3.07 2.91 2.71 2.22 2.24 2016 2.50 2.25 1.86 1.92 1.91 2.3

  12. Detroit, MI Natural Gas Pipeline Exports to Canada (Million Cubic Feet)

    U.S. Energy Information Administration (EIA) Indexed Site

    Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 1990's 30,410 31,080 24,908 25,049 2000's 36,007 35,644 7,431 19,737 40,030 40,255 22,156 22,904 27,220 43,980 2010's 44,275 43,690 50,347 50,439 46,981 37,528

  13. Detroit, MI Natural Gas Pipeline Exports to Canada (Million Cubic Feet)

    U.S. Energy Information Administration (EIA) Indexed Site

    Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2011 3,465 2,693 3,676 3,988 3,357 3,437 765 3,916 4,318 4,473 4,851 4,752 2012 5,562 5,372 5,253 3,745 3,354 2,811 2,935 3,822 4,015 4,113 4,636 4,728 2013 4,791 4,331 4,801 3,571 4,430 3,769 3,933 4,131 3,885 2,862 3,886 4,945 2014 4,042 4,259 4,171 3,540 3,852 4,008 3,643 3,461 3,414 4,013 3,800 4,779 2015 3,753 2,420 4,176 2,416 2,035 1,911 2,624 2,674 4,755 4,944 3,048 2,773 2016 2,881 2,701 3,427 1,402 1,301 2,806

  14. Detroit, MI Natural Gas Pipeline Imports From Canada (Dollars per Thousand

    U.S. Energy Information Administration (EIA) Indexed Site

    Cubic Feet) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 1990's 2.75 2.51 2.43 2.51 2000's 3.82 9.34 3.56 5.96 6.27 -- -- 8.28 6.58 4.53 2010's 8.37 5.17 -- 4.4

  15. Detroit, MI Natural Gas Pipeline Imports From Canada (Dollars per Thousand

    U.S. Energy Information Administration (EIA) Indexed Site

    Cubic Feet) Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2011 4.95 5.33 2013 3.80 4.50 4.09 4.63 201

  16. Detroit, MI Natural Gas Pipeline Imports From Canada (Million Cubic Feet)

    U.S. Energy Information Administration (EIA) Indexed Site

    Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 1990's 14,901 11,501 10,925 7,671 2000's 6,171 405 1,948 2,514 1,117 0 0 81 753 21 2010's 79 19 0 165

  17. Detroit, MI Natural Gas Pipeline Imports From Canada (Million Cubic Feet)

    U.S. Energy Information Administration (EIA) Indexed Site

    Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2011 8 11 2013 16 140 24 10 2014

  18. The Detroit Diesel DELTA Engine for Light Trucks and SUVs - Year 2000 Update

    SciTech Connect (OSTI)

    Nabil S. Hakim; Charles E. Freese; Stanley P. Miller

    2000-06-19

    Detroit Diesel Corporation (DDC) is developing the DELTA 4.0L V6 engine, specifically for the North American light truck market. This market poses unique requirements for a diesel engine, necessitating a clean sheet engine design. DELTA was developed from a clean sheet of paper, with the first engine firing just 228 days later. The process began with a Quality Function Deployment (QFD) analysis, which prioritized the development criteria. The development process integrated a co-located, fully cross-functional team. Suppliers were fully integrated and maintained on-site representation. The first demonstration vehicle moved under its own power 12 weeks after the first engine fired. It was demonstrated to the automotive press 18 days later. DELTA has repeatedly demonstrated its ability to disprove historical North American diesel perceptions and compete directly with gasoline engines. This paper outlines the Generation 0.0 development process and briefly defines the engine. A brief indication of the Generation 0.5 development status is given.

  19. Post Mortem of 120k mi Light-Duty Urea SCR and DPF System | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Post Mortem of 120k mi Light-Duty Urea SCR and DPF System Post Mortem of 120k mi Light-Duty Urea SCR and DPF System Presentation given at the 2007 Diesel Engine-Efficiency & Emissions Research Conference (DEER 2007). 13-16 August, 2007, Detroit, Michigan. Sponsored by the U.S. Department of Energy's (DOE) Office of FreedomCAR and Vehicle Technologies (OFCVT). deer07_lambert.pdf (649.68 KB) More Documents & Publications Urea SCR and DPF System for Tier 2 Diesel Light-Duty

  20. Detroit Edison's Fermi 1 - Preparation for Reactor Removal

    SciTech Connect (OSTI)

    Swindle, Danny [Sargent and Lundy Engineers, LLC, 55 E. Monroe Street, Chicago, IL 60603 (United States)

    2008-01-15

    This paper is intended to provide information about the ongoing decommissioning tasks at Detroit Edison's Fermi 1 plant, and in particular, the work being performed to prepare the reactor for removal and disposal. In 1972 Fermi 1 was shutdown and the fuel returned to the Atomic Energy Commission. By the end of 1975, a retirement plan was prepared, the bulk sodium removed, and the plant placed in a safe store condition. The plant systems were left isolated with the sodium containing systems inert with carbon dioxide in an attempt to form a carbonate layer, thus passivating the underlying reactive sodium. In 1996, Detroit Edison determined to evaluate the condition of the plant and to make recommendations in relation to the Fermi 1 future plans. At the end of 1997 approval was obtained to remove the bulk asbestos and residual alkali-metals (i.e., sodium and sodium potassium (NaK)). In 2000, full nuclear decommissioning of the plant was approved. To date, the bulk asbestos insulation has been removed, and the only NaK remaining is located in six capillary instrument tubes. The remaining sodium is contained within the reactor, two of the three primary loops, and miscellaneous removed pipes and equipment to be processed. The preferred method for removing or reacting sodium at Fermi 1 is by injecting superheated steam into a heated, nitrogen inert system. The byproducts of this reaction are caustic sodium hydroxide, hydrogen gas, and heat. The decision was made to separate the three primary loops from the reactor for better control prior to processing each loop and the reactor separately. The first loop has already been processed. The main focus is now to process the reactor to allow removal and disposal of the Class C waste prior to the anticipated June 2008 closure of the Barnwell radioactive waste disposal facility located in South Carolina. Lessons learnt are summarized and concern: the realistic schedule and adherence to the schedule, time estimates, personnel

  1. 2014 SSL Market Development Workshop Presentations and Materials |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy SSL Market Development Workshop Presentations and Materials 2014 SSL Market Development Workshop Presentations and Materials Download presentations from the 2014 Solid-State Lighting Market Development Workshop, held November 12-13 in Detroit, Michigan. Please note, not all of the workshop speakers presented slides. Workshop Video and Highlights Agenda Day 1 Workshop Welcome James Brodrick, U.S. Department of Energy Tuning the Spectrum: Light, Health, and the Pursuit of

  2. Measurement of the direct <mi>CP> -violating parameter <mi>Ami><mi>CP> in the decay <mi>D>+<mi>Kmi>-<mimi>+<mi>π>+

    SciTech Connect (OSTI)

    Abazov, V. M.; Abbott, B.; Acharya, B. S.; Adams, M.; Adams, T.; Agnew, J. P.; Alexeev, G. D.; Alkhazov, G.; Alton, A.; Askew, A.; Atkins, S.; Augsten, K.; Avila, C.; Badaud, F.; Bagby, L.; Baldin, B.; Bandurin, D. V.; Banerjee, S.; Barberis, E.; Baringer, P.; Bartlett, J. F.; Bassler, U.; Bazterra, V.; Bean, A.; Begalli, M.; Bellantoni, L.; Beri, S. B.; Bernardi, G.; Bernhard, R.; Bertram, I.; Besançon, M.; Beuselinck, R.; Bhat, P. C.; Bhatia, S.; Bhatnagar, V.; Blazey, G.; Blessing, S.; Bloom, K.; Boehnlein, A.; Boline, D.; Boos, E. E.; Borissov, G.; Borysova, M.; Brandt, A.; Brandt, O.; Brock, R.; Bross, A.; Brown, D.; Bu, X. B.; Buehler, M.; Buescher, V.; Bunichev, V.; Burdin, S.; Buszello, C. P.; Camacho-Pérez, E.; Casey, B. C. K.; Castilla-Valdez, H.; Caughron, S.; Chakrabarti, S.; Chan, K. M.; Chandra, A.; Chapon, E.; Chen, G.; Cho, S. W.; Choi, S.; Choudhary, B.; Cihangir, S.; Claes, D.; Clutter, J.; Cooke, M.; Cooper, W. E.; Corcoran, M.; Couderc, F.; Cousinou, M. -C.; Cutts, D.; Das, A.; Davies, G.; de Jong, S. J.; De La Cruz-Burelo, E.; Déliot, F.; Demina, R.; Denisov, D.; Denisov, S. P.; Desai, S.; Deterre, C.; DeVaughan, K.; Diehl, H. T.; Diesburg, M.; Ding, P. F.; Dominguez, A.; Dubey, A.; Dudko, L. V.; Duperrin, A.; Dutt, S.; Eads, M.; Edmunds, D.; Ellison, J.; Elvira, V. D.; Enari, Y.; Evans, H.; Evdokimov, V. N.; Fauré, A.; Feng, L.; Ferbel, T.; Fiedler, F.; Filthaut, F.; Fisher, W.; Fisk, H. E.; Fortner, M.; Fox, H.; Fuess, S.; Garbincius, P. H.; Garcia-Bellido, A.; García-González, J. A.; Gavrilov, V.; Geng, W.; Gerber, C. E.; Gershtein, Y.; Ginther, G.; Gogota, O.; Golovanov, G.; Grannis, P. D.; Greder, S.; Greenlee, H.; Grenier, G.; Gris, Ph.; Grivaz, J. -F.; Grohsjean, A.; Grünendahl, S.; Grünewald, M. W.; Guillemin, T.; Gutierrez, G.; Gutierrez, P.; Haley, J.; Han, L.; Harder, K.; Harel, A.; Hauptman, J. M.; Hays, J.; Head, T.; Hebbeker, T.; Hedin, D.; Hegab, H.; Heinson, A. P.; Heintz, U.; Hensel, C.; Heredia-De La Cruz, I.; Herner, K.; Hesketh, G.; Hildreth, M. D.; Hirosky, R.; Hoang, T.; Hobbs, J. D.; Hoeneisen, B.; Hogan, J.; Hohlfeld, M.; Holzbauer, J. L.; Howley, I.; Hubacek, Z.; Hynek, V.; Iashvili, I.; Ilchenko, Y.; Illingworth, R.; Ito, A. S.; Jabeen, S.; Jaffré, M.; Jayasinghe, A.; Jeong, M. S.; Jesik, R.; Jiang, P.; Johns, K.; Johnson, E.; Johnson, M.; Jonckheere, A.; Jonsson, P.; Joshi, J.; Jung, A. W.; Juste, A.; Kajfasz, E.; Karmanov, D.; Katsanos, I.; Kaur, M.; Kehoe, R.; Kermiche, S.; Khalatyan, N.; Khanov, A.; Kharchilava, A.; Kharzheev, Y. N.; Kiselevich, I.; Kohli, J. M.; Kozelov, A. V.; Kraus, J.; Kumar, A.; Kupco, A.; Kurča, T.; Kuzmin, V. A.; Lammers, S.; Lebrun, P.; Lee, H. S.; Lee, S. W.; Lee, W. M.; Lei, X.; Lellouch, J.; Li, D.; Li, H.; Li, L.; Li, Q. Z.; Lim, J. K.; Lincoln, D.; Linnemann, J.; Lipaev, V. V.; Lipton, R.; Liu, H.; Liu, Y.; Lobodenko, A.; Lokajicek, M.; Lopes de Sa, R.; Luna-Garcia, R.; Lyon, A. L.; Maciel, A. K. A.; Madar, R.; Magaña-Villalba, R.; Malik, S.; Malyshev, V. L.; Mansour, J.; Martínez-Ortega, J.; McCarthy, R.; McGivern, C. L.; Meijer, M. M.; Melnitchouk, A.; Menezes, D.; Mercadante, P. G.; Merkin, M.; Meyer, A.; Meyer, J.; Miconi, F.; Mondal, N. K.; Mulhearn, M.; Nagy, E.; Narain, M.; Nayyar, R.; Neal, H. A.; Negret, J. P.; Neustroev, P.; Nguyen, H. T.; Nunnemann, T.; Orduna, J.; Osman, N.; Osta, J.; Pal, A.; Parashar, N.; Parihar, V.; Park, S. K.; Partridge, R.; Parua, N.; Patwa, A.; Penning, B.; Perfilov, M.; Peters, Y.; Petridis, K.; Petrillo, G.; Pétroff, P.; Pleier, M. -A.; Podstavkov, V. M.; Popov, A. V.; Prewitt, M.; Price, D.; Prokopenko, N.; Qian, J.; Quadt, A.; Quinn, B.; Ratoff, P. N.; Razumov, I.; Ripp-Baudot, I.; Rizatdinova, F.; Rominsky, M.; Ross, A.; Royon, C.; Rubinov, P.; Ruchti, R.; Sajot, G.; Sánchez-Hernández, A.; Sanders, M. P.; Santos, A. S.; Savage, G.; Savitskyi, M.; Sawyer, L.; Scanlon, T.; Schamberger, R. D.; Scheglov, Y.; Schellman, H.; Schwanenberger, C.; Schwienhorst, R.; Sekaric, J.; Severini, H.; Shabalina, E.; Shary, V.; Shaw, S.; Shchukin, A. A.; Simak, V.; Skubic, P.; Slattery, P.; Smirnov, D.; Snow, G. R.; Snow, J.; Snyder, S.; Söldner-Rembold, S.; Sonnenschein, L.; Soustruznik, K.; Stark, J.; Stoyanova, D. A.; Strauss, M.; Suter, L.; Svoisky, P.; Titov, M.; Tokmenin, V. V.; Tsai, Y. -T.; Tsybychev, D.; Tuchming, B.; Tully, C.; Uvarov, L.; Uvarov, S.; Uzunyan, S.; Van Kooten, R.; van Leeuwen, W. M.; Varelas, N.; Varnes, E. W.; Vasilyev, I. A.; Verkheev, A. Y.; Vertogradov, L. S.; Verzocchi, M.; Vesterinen, M.; Vilanova, D.; Vokac, P.; Wahl, H. D.; Wang, M. H. L. S.; Warchol, J.; Watts, G.; Wayne, M.; Weichert, J.; Welty-Rieger, L.; Williams, M. R. J.; Wilson, G. W.; Wobisch, M.; Wood, D. R.; Wyatt, T. R.; Xie, Y.; Yamada, R.; Yang, S.; Yasuda, T.; Yatsunenko, Y. A.; Ye, W.; Ye, Z.; Yin, H.; Yip, K.; Youn, S. W.; Yu, J. M.; Zennamo, J.; Zhao, T. G.; Zhou, B.; Zhu, J.; Zielinski, M.; Zieminska, D.; Zivkovic, L.

    2014-12-01

    We measure the direct mi>Cmi>mi>P>-violating parameter mi>Ami>mi>Cmi>mi>Pmi> for the decay of the charged charm meson, mi>Dmi>+mi>Kmi>-mi>πmi>+mi>πmi>+ (and charge conjugate), using the full 10.4 mi>fbmi>-1 sample of mi>p>mi>p>¯ collisions at mi>smi>=1.96 mi>TeVmi> collected by the D0 detector at the Fermilab Tevatron collider. We extract the raw reconstructed charge asymmetry by fitting the invariant mass distributions for the sum and difference of charge-specific samples. This quantity is then corrected for detector-related asymmetries using data-driven methods and for possible physics asymmetries (from mi>B>mi>D

  3. Rotary engine design: Analysis and developments; Proceedings of the International Congress and Exposition, Detroit, MI, Feb. 27-Mar. 3, 1989

    SciTech Connect (OSTI)

    Not Available

    1989-01-01

    The present conference on the development status of Wankel cycle rotary engine design discusses stratified-charge rotary engine features, techniques for noise and vibration reduction in rotary engines, testing methods for insulated rotary engine components, cyclic combustion variation in rotary engines, and a combustion model for homogeneous charge natural gas rotary engines. Also discussed are fuel-air mixing and distribution in a direct-injection stratified-charge rotary engine, the 'rotary-vee' engine design concept, strain measurements in a rotary engine housing, and a comparison of computed and measured pressure in a premixed-charge natural gas-fueled rotary engine.

  4. DTE Energy Technologies With Detroit Edison Co. and Kinectrics Inc.: Distributed Resources Aggregation Modeling and Field Configuration Testing

    SciTech Connect (OSTI)

    Not Available

    2003-10-01

    Summarizes the work of DTE Energy Technologies, Detroit Edison, and Kinectrics, under contract to DOE's Distribution and Interconnection R&D, to develop distributed resources aggregation modeling and field configuration testing.

  5. The not so new electric car -- Step child of Detroit

    SciTech Connect (OSTI)

    Lough, S.S.

    1994-12-31

    In the first decade of the 20th century, gas and electric vehicles were in a head to head battle. Actually until after 1915, electric trucks dominated the urban scene. At this time it was not only commercial concerns who preferred electric`s but women too, for they were clean, easy to start and drive, and you know something--they still are! In lacking the foresight to develop electric car technology the US has created a global monster. Urban sprawl, suburbs, malls, pollution on a global scale, and an infrastructure which is not going to give up market share without a fight.

  6. The Ninth Annual DOE Solid-State Lighting Market Development Workshop |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Information Resources » Conferences & Meetings » Past Conferences » The Ninth Annual DOE Solid-State Lighting Market Development Workshop The Ninth Annual DOE Solid-State Lighting Market Development Workshop Nearly 200 lighting leaders from across North America gathered in Detroit from November 12-13, 2014, for the ninth annual Solid-State Lighting (SSL) Market Development Workshop, hosted by DOE. The diverse audience spanned the spectrum of SSL stakeholders,

  7. Advanced Communication and Control of Distributed Energy Resources at Detroit Edison

    SciTech Connect (OSTI)

    Haukur Asgeirsson; Richard Seguin

    2004-01-31

    The project objective was to create the communication and control system, the process and the economic procedures that will allow owners (e.g., residential, commercial, industrial, manufacturing, etc.) of Distributed Energy Resources (DER) connected in parallel to the electric distribution to have their resources operated in a manner that protects the electric utility distribution network and personnel that may be working on the network. The Distribution Engineering Workstation (DEW) (a power flow and short circuit modeling tool) was modified to calculate the real-time characteristics of the distribution network based on the real-time electric distribution network information and provide DER operating suggestions to the Detroit Edison system operators so that regional electric stability is maintained. Part of the suggestion algorithm takes into account the operational availability of DERs, which is known by the Energy Aggregator, DTE Energy Technologies. The availability information will be exchanged from DTE Energy Technologies to Detroit Edison. For the calculated suggestions to be used by the Detroit Edison operators, procedures were developed to allow an operator to operate a DER by requesting operation of the DER through DTE Energy Technologies. Prior to issuing control of a DER, the safety of the distribution network and personnel needs to be taken into account. This information will be exchanged from Detroit Edison to DTE Energy Technologies. Once it is safe to control the DER, DTE Energy Technologies will issue the control signal. The real-time monitoring of the DECo system will reflect the DER control. Multi-vendor DER technologies representing approximately 4 MW of capacity was monitored and controlled using a web-based communication path. The DER technologies included are a photovoltaic system, energy storage, fuel cells and natural gas/diesel internal combustion engine generators. This report documents Phase I result for the Detroit Edison (Utility

  8. Evaluation of Fish Passage Conditions for Juvenile Salmonids Using Sensor Fish at Detroit Dam, Oregon

    SciTech Connect (OSTI)

    Duncan, Joanne P.

    2010-01-29

    Fish passage conditions through two spillways at Detroit Dam on the North Santiam River in Oregon were evaluated by Pacific Northwest National Laboratory for the U.S. Army Corps of Engineers (USACE), Portland District, using Sensor Fish devices. The objective of the study was to describe and compare passage exposure conditions through Spillbay 3 and Spillbay 6 at 1.5- and 3.5-ft gate openings, identifying potential fish injury regions of the routes. The study was performed in July 2009, concurrent with HI-Z balloon-tag studies by Normandeau Associates, Inc. Sensor Fish and live fish were deployed at elevations approximately 3 ft above structure at depths determined using a computational fluid dynamics model. Data collected were analyzed to estimate 1) exposure conditions, particularly exposure to severe collision and shear events by passage route sub-regions; 2) differences in passage conditions between passage routes; and 3) relationships to live-fish injury and mortality data estimates.

  9. Coal-water-slurry autoignition in a high-speed Detroit diesel engine

    SciTech Connect (OSTI)

    Schwalb, J.A.; Ryan, T.W. III.; Kakwani, R.M.; Winsor, R.E.

    1994-10-01

    Autoignition of coal-water-slurry (CWS) fuel in a two-stroke engine operating at 1900 RPM has been achieved. A Pump-Line-Nozzle (PLN) injection system, delivering 400mm{sup 3} injection of CWS, was installed in one modified cylinder of a Detroit Diesel Corporation (DDC) 8V-149TI engine, while the other seven cylinders remained configured for diesel fuel. Coal Combustion was sustained by maintaining high gas and surface temperatures with a combination of hot residual gases, warm inlet air admission, ceramic insulated components and increased compression ratio. The coal-fueled cylinder generated 85kW indicated power (80 percent of rated power), and lower NO{sub x} levels with a combustion efficiency of 99.2 percent. 6 refs., 15 figs., 4 tabs.

  10. Field Demonstration of a 24-kV Superconducting Cable at Detroit Edison

    SciTech Connect (OSTI)

    Kelley, Nathan; Corsaro, Pietro

    2004-12-01

    Customer acceptance of high temperature superconducting (HTS) cable technology requires a substantial field demonstration illustrating both the system's technical capabilities and its suitability for installation and operation within the utility environment. In this project, the world's first underground installation of an HTS cable using existing ductwork, a 120 meter demonstration cable circuit was designed and installed between the 24 kV bus distribution bus and a 120 kV-24 kV transformer at Detroit Edison's Frisbie substation. The system incorporated cables, accessories, a refrigeration system, and control instrumentation. Although the system was never put in operation because of problems with leaks in the cryostat, the project significantly advanced the state-of-the-art in the design and implementation of Warm Dielectric cable systems in substation applications. Lessons learned in this project are already being incorporated in several ongoing demonstration projects.

  11. Real-time sub-<mi>>ngstrom...

    Office of Scientific and Technical Information (OSTI)

    Real-time sub-<mi>>ngstrom imaging of reversible and irreversible conformations in rhodium catalysts and graphene Kisielowski, Christian; Wang,...

  12. Mi GmbH | Open Energy Information

    Open Energy Info (EERE)

    Mi GmbH Jump to: navigation, search Name: Mi GmbH Place: Switzerland Zip: CH-6340 Sector: Solar Product: Baar-based manufacturer and distributor of fruit juices. The firm is also...

  13. miRNAs in brain development

    SciTech Connect (OSTI)

    Petri, Rebecca; Malmevik, Josephine; Fasching, Liana; Åkerblom, Malin; Jakobsson, Johan

    2014-02-01

    MicroRNAs (miRNAs) are small, non-coding RNAs that negatively regulate gene expression at the post-transcriptional level. In the brain, a large number of miRNAs are expressed and there is a growing body of evidence demonstrating that miRNAs are essential for brain development and neuronal function. Conditional knockout studies of the core components in the miRNA biogenesis pathway, such as Dicer and DGCR8, have demonstrated a crucial role for miRNAs during the development of the central nervous system. Furthermore, mice deleted for specific miRNAs and miRNA-clusters demonstrate diverse functional roles for different miRNAs during the development of different brain structures. miRNAs have been proposed to regulate cellular functions such as differentiation, proliferation and fate-determination of neural progenitors. In this review we summarise the findings from recent studies that highlight the importance of miRNAs in brain development with a focus on the mouse model. We also discuss the technical limitations of current miRNA studies that still limit our understanding of this family of non-coding RNAs and propose the use of novel and refined technologies that are needed in order to fully determine the impact of specific miRNAs in brain development. - Highlights: • miRNAs are essential for brain development and neuronal function. • KO of Dicer is embryonically lethal. • Conditional Dicer KO results in defective proliferation or increased apoptosis. • KO of individual miRNAs or miRNA families is necessary to determine function.

  14. SCReaming for Low NOx - SCR for the Light Duty Market | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy SCReaming for Low NOx - SCR for the Light Duty Market SCReaming for Low NOx - SCR for the Light Duty Market Presentation given at DEER 2006, August 20-24, 2006, Detroit, Michigan. Sponsored by the U.S. DOE's EERE FreedomCar and Fuel Partnership and 21st Century Truck Programs. 2006_deer_traver.pdf (260.76 KB) More Documents & Publications Validated SCR Concept Development Simulation and Analysis of HP/LP EGR for Heavy-Duty Applications New Demands on Heavy Duty Engine Management

  15. Hydroacoustic Evaluation of Juvenile Salmonid Passage and Distribution at Detroit Dam, 2011

    SciTech Connect (OSTI)

    Khan, Fenton; Royer, Ida M.; Johnson, Gary E.; Ham, Kenneth D.

    2012-11-15

    Pacific Northwest National Laboratory evaluated juvenile salmonid passage and distribution at Detroit Dam (DET) on the North Santiam River, Oregon for the U.S. Army Corps of Engineers (USACE) to provide data to support decisions on long-term measures to enhance downstream passage at DET and others dams in USACE’s Willamette Valley Project. This study was conducted in response to regulatory requirements necessitated by the listing of Upper Willamette River Spring Chinook salmon (Oncorhynchus tshawytscha) and Upper Willamette River steelhead (O. mykiss) as threatened under the Endangered Species Act. The goal of the study was to provide information of juvenile salmonid passage and distribution at DET from February 2011 through February 2012. The results of the hydroacoustic study provide new and, in some cases, first-ever data on passage estimates, run timing, distributions, and relationships between fish passage and environmental variables at the dam. This information will inform management decisions on the design and development of surface passage and collection devices to help restore Chinook salmon populations in the North Santiam River watershed above DET. During the entire study period, an estimated total of 182,526 smolt-size fish (±4,660 fish, 95% CI) passed through turbine penstock intakes. Run timing peaked in winter and early spring months. Passage rates were highest during late fall, winter and early spring months and low during summer. Horizontal distribution for hours when both turbine units were operated simultaneously indicated Unit 2 passed almost twice as much fish as Unit 1. Diel distribution for smolt-size fish during the study period was fairly uniform, indicating fish were passing the turbines at all times of the day. A total of 5,083 smolt-size fish (± 312 fish, 95% CI) were estimated passed via the spillway when it was open between June 23 and September 27, 2011. Daily passage was low at the spillway during the June-August period, and

  16. DOE - Office of Legacy Management -- Michigan Velsicol Chemical Corp - MI

    Office of Legacy Management (LM)

    03 Michigan Velsicol Chemical Corp - MI 03 FUSRAP Considered Sites Site: MICHIGAN [VELSICOL] CHEMICAL CORP. (MI.03 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: Velsicol Chemical Corp. MI.03-1 Location: St. Louis , Michigan MI.03-2 Evaluation Year: Circa 1987 MI.03-3 Site Operations: Rare earth processing facility. MI.03-2 Site Disposition: Eliminated - No Authority - NRC survey MI.03-3 Radioactive Materials Handled: Yes Primary Radioactive

  17. DOE - Office of Legacy Management -- Star Cutter Corp - MI 15

    Office of Legacy Management (LM)

    Star Cutter Corp - MI 15 FUSRAP Considered Sites Site: STAR CUTTER CORP. (MI.15) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Farmington , Michigan MI.15-1 Evaluation Year: 1991 MI.15-2 Site Operations: Performed a one time uranium slug drilling operation test in 1956. MI.15-3 MI.15-1 Site Disposition: Eliminated - Potential for contamination considered remote based on limited scope and quantity of materials handled MI.15-2 Radioactive

  18. Gratiot | Open Energy Information

    Open Energy Info (EERE)

    Wind energy Facility Type Commercial Scale Wind Facility Status In Service Owner Detroit Edison Developer Invenergy Energy Purchaser Detroit Edison Location Breckenridge MI...

  19. DOE - Office of Legacy Management -- Adrian - MI 01

    Office of Legacy Management (LM)

    Adrian - MI 01 FUSRAP Considered Sites Adrian, MI Alternate Name(s): Bridgeport Brass Co. Special Metals Extrusion Plant Bridgeport Brass Company General Motors General Motors Company, Adrian MI.01-1 Location: 1450 East Beecher Street, Adrian, Michigan MI.01-3 Historical Operations: Performed uranium extrusion research and development and metal fabrication work for the AEC using uranium, thorium, and plutonium. MI.01-2 Eligibility Determination: Eligible MI.01-1 Radiological Survey(s):

  20. Marketing Resources

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Expand Utility Resources News & Events Expand News & Events Skip navigation links Marketing Resources Marketing Portal Reports, Publications, and Research Utility Toolkit...

  1. Economic Potential of CHP in Detroit Edison Service Area: the Customer Perspective

    SciTech Connect (OSTI)

    Kelly, J.

    2003-10-10

    DOE's mission under the Distributed Energy and Electricity Reliability (DEER) Program is to strengthen America's electric energy infrastructure and provide utilities and consumers with a greater array of energy-efficient technology choices for generating, transmitting, distributing, storing, and managing demand for electric power and thermal energy. DOE recognizes that distributed energy technologies can help accomplish this mission. Distributed energy (DE) technologies have received much attention for the potential energy savings and electric power reliability assurances that may be achieved by their widespread adoption. Fueling the attention has been the desire to reduce greenhouse gas emissions and concern about easing power transmission and distribution system capacity limitations and congestion. However, these benefits may come at a cost to the electric utility companies in terms of lost revenue and other potential impacts on the distribution system. It is important to assess the costs and benefits of DE to consumers and distribution system companies. DOE commissioned this study to assess the costs and benefits of DE technologies to consumers and to better understand the effect of DE on the grid. Current central power generation units vent more waste heat (energy) than the entire transportation sector consumes and this wasted thermal energy is projected to grow by 45% within the next 20 years. Consumer investment in technologies that increase power generation efficiency is a key element of the DOE Energy Efficiency program. The program aims to increase overall cycle efficiency from 30% to 70% within 20 years as well. DOE wants to determine the impact of DE in several small areas within cities across the U.S. Ann Arbor, Michigan, was chosen as the city for this case study. Ann Arbor has electric and gas rates that can substantially affect the market penetration of DE. This case study analysis was intended to: (1) Determine what DE market penetration can

  2. DOE - Office of Legacy Management -- Oliver Corp - MI 11

    Office of Legacy Management (LM)

    Oliver Corp - MI 11 FUSRAP Considered Sites Site: OLIVER CORP. (MI.11 ) Eliminated from further consideration under FUSRAP - Referred to NRC Designated Name: Not Designated Alternate Name: Behnke Warehousing Incorporated MI.11-1 Location: 433 East Michigan Avenue , Battle Creek , Michigan MI.11-1 Evaluation Year: 1986 MI.11-4 Site Operations: Conducted production scale briquetting of green salt and magnesium blend under AEC license Nos. SNM-591, SUB-579, and C-3725. MI.11-1 MI.11-3 Site

  3. The NuMI Neutrino Beam

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Adamson, P.; Anderson, K.; Andrews, M.; Andrews, R.; Anghel, I.; Augustine, D.; Aurisano, A.; Avvakumov, S.; Ayres, D. S.; Baller, B.; et al

    2015-10-20

    Our paper describes the hardware and operations of the Neutrinos at the Main Injector (NuMI) beam at Fermilab. It elaborates on the design considerations for the beam as a whole and for individual elements. The most important part of our design details pertaining to individual components is described. Beam monitoring systems and procedures, including the tuning and alignment of the beam and NuMI long-term performance, are also discussed.

  4. Marketing and Market Transformation | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Marketing and Market Transformation Marketing and Market Transformation Presents how going green will grow your business, as well as how programs can overcome appraisal challenges. ...

  5. Market Transformation

    SciTech Connect (OSTI)

    Not Available

    2008-09-01

    Summarizes the goals and activities of the DOE Solar Energy Technologies Program efforts within its market transformation subprogram.

  6. Characterization of Fish Passage Conditions through a Francis Turbine, Spillway, and Regulating Outlet at Detroit Dam, Oregon, Using Sensor Fish, 2009

    SciTech Connect (OSTI)

    Duncan, Joanne P.; Carlson, Thomas J.

    2011-05-06

    Fish passage conditions through two spillways, a Francis turbine, and a regulating outlet (RO) at Detroit Dam on the North Santiam River in Oregon were evaluated by Pacific Northwest National Laboratory for the U.S. Army Corps of Engineers (USACE), Portland District, using Sensor Fish devices. The objective of the study was to describe and compare passage exposure conditions, identifying potential fish injury regions within the routes. The study was performed in July, October, and December 2009 concurrent with HI-Z balloon-tag studies by Normandeau Associates, Inc. Sensor Fish data were analyzed to estimate 1) exposure conditions, particularly exposure to severe strike, collision, and shear events by passage route sub-regions; 2) differences in passage conditions between passage routes; and 3) relationships to live-fish injury and mortality data estimates. Comparison of the three passage routes evaluated at Detroit Dam indicates that the RO passage route through the 5-ft gate opening was relatively the safest route for fish passage under the operating conditions tested; turbine passage was the most deleterious. These observations were supported also by the survival and malady estimates obtained from live-fish testing. Injury rates were highest for turbine and spillway passage. However, none of the passage routes tested is safe for juvenile salmonid passage.

  7. Market Transformation

    Fuel Cell Technologies Publication and Product Library (EERE)

    This Fuel Cell Technologies Program fact sheet outlines current status and challenges in the market transformation of hydrogen and fuel cell technologies.

  8. Market Acceleration

    SciTech Connect (OSTI)

    Solar Energy Technologies Program

    2010-09-28

    The fact sheet summarizes the goals and activities of the DOE Solar Energy Technologies Program efforts within its market acceleration subprogram.

  9. Energy Markets

    U.S. Energy Information Administration (EIA) Indexed Site

    will show a lower growth trajectory Source: EIA, International Energy Outlook 2013 carbon dioxide emissions billion metric tons 6 CSIS | Energy Markets Outlook November 16,...

  10. Market Transformation

    SciTech Connect (OSTI)

    2011-02-15

    This Fuel Cell Technologies Program fact sheet outlines current status and challenges in the market transformation of hydrogen and fuel cell technologies.

  11. DOE - Office of Legacy Management -- Naval Ordnance Plant - MI...

    Office of Legacy Management (LM)

    Eliminated from further consideration under FUSRAP - Referred to DoD for action Designated ... MI.0-03-1 Site Disposition: Eliminated - No Authority - Referred to DoD MI.0-03-1 ...

  12. miR-132 and miR-212 are increased in pancreatic cancer and target the retinoblastoma tumor suppressor

    SciTech Connect (OSTI)

    Park, Jong-Kook; Henry, Jon C.; Jiang, Jinmai; Esau, Christine; Gusev, Yuriy; Lerner, Megan R.; Postier, Russell G.; Brackett, Daniel J.; Schmittgen, Thomas D.

    2011-03-25

    Research highlights: {yields} The expression of miR-132 and miR-212 are significantly increased in pancreatic cancer. {yields} miR-132 and miR-212 target the tumor suppressor pRb, resulting in enhanced proliferation. {yields} miR-132 and miR-212 expression is increased by a {beta}2 adrenergic receptor agonist, suggesting a novel mechanism for pancreatic cancer progression. -- Abstract: Numerous microRNAs (miRNAs) are reported as differentially expressed in cancer, however the consequence of miRNA deregulation in cancer is unknown for many miRNAs. We report that two miRNAs located on chromosome 17p13, miR-132 and miR-212, are over-expressed in pancreatic adenocarcinoma (PDAC) tissues. Both miRNAs are predicted to target the retinoblastoma tumor suppressor, Rb1. Validation of this interaction was confirmed by luciferase reporter assay and western blot in a pancreatic cancer cell line transfected with pre-miR-212 and pre-miR-132 oligos. Cell proliferation was enhanced in Panc-1 cells transfected with pre-miR-132/-212 oligos. Conversely, antisense oligos to miR-132/-212 reduced cell proliferation and caused a G{sub 2}/M cell cycle arrest. The mRNA of a number of E2F transcriptional targets were increased in cells over expressing miR-132/-212. Exposing Panc-1 cells to the {beta}2 adrenergic receptor agonist, terbutaline, increased the miR-132 and miR-212 expression by 2- to 4-fold. We report that over-expression of miR-132 and miR-212 result in reduced pRb protein in pancreatic cancer cells and that the increase in cell proliferation from over-expression of these miRNAs is likely due to increased expression of several E2F target genes. The {beta}2 adrenergic pathway may play an important role in this novel mechanism.

  13. “Nodal Gap” induced by the incommensurate diagonal spin density modulation in underdoped high- <mi>Tmi>c> superconductors

    SciTech Connect (OSTI)

    Zhou, Tao; Gao, Yi; Zhu, Jian -Xin

    2015-03-07

    Recently it was revealed that the whole Fermi surface is fully gapped for several families of underdoped cuprates. The existence of the finite energy gap along the <mi>d>-wave nodal lines (nodal gap) contrasts the common understanding of the <mi>d>-wave pairing symmetry, which challenges the present theories for the high-<mi>Tmi><mi>c>superconductors. Here we propose that the incommensurate diagonal spin-density-wave order can account for the above experimental observation. The Fermi surface and the local density of states are also studied. Our results are in good agreement with many important experiments in high-<mi>Tmi><mi>c>superconductors.

  14. Detroit Commuter Hydrogen Project

    Office of Energy Efficiency and Renewable Energy (EERE)

    2009 DOE Hydrogen Program and Vehicle Technologies Program Annual Merit Review and Peer Evaluation Meeting, May 18-22, 2009 -- Washington D.C.

  15. Characterization of function and regulation of miR-24-1 and miR-31

    SciTech Connect (OSTI)

    Sun Fenyong; Wang Jiayi; Pan Qiuhui; Yu Yongchun; Zhang Yue; Wan Yang; Wang Ju; Li Xiaoyan; Hong An

    2009-03-13

    To date, numerous microRNAs (miRNAs) have been discovered. However, the function of these miRNAs is largely unknown. While our knowledge of miRNA post-transcriptional processing has greatly expanded in recent years, we have a limited understanding of the regulation and transcription of miRNA genes. In this study, we characterized two BMP-2 upregulated miRNAs, miR-24-1 and miR-31, in mesenchymal stem cells and showed their opposing function in controlling cellular proliferation, and adipogenesis. Furthermore, we are the first to identify and characterize mouse intronic miR-23b{approx}27b{approx}24-1 and intergenic miR-31 genes. Moreover, we found that pri-miR-23b, pri-miR-27b, and pri-miR-24-1 are transcribed independently and their expression profiles are unique when cells are treated with BMP-2, even though they are located closely together.

  16. Energy Markets

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Energy Markets November 16, 2015 0 2 4 6 8 10 1990 1994 1998 2002 2006 2010 2014 biofuels geothermal solar wind waste hydroelectric wood 0 2 4 6 8 10 1990 1994 1998 2002 2006 2010...

  17. Energy Markets

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Energy Markets October 22, 2015 0 2 4 6 8 10 1990 1994 1998 2002 2006 2010 2014 biofuels geothermal solar wind waste hydroelectric wood 0 2 4 6 8 10 1990 1994 1998 2002 2006 2010...

  18. Energy Markets

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Energy Markets October 29, 2015 0 2 4 6 8 10 1990 1994 1998 2002 2006 2010 2014 biofuels geothermal solar wind waste hydroelectric wood 0 2 4 6 8 10 1990 1994 1998 2002 2006 2010...

  19. DOE - Office of Legacy Management -- Dow Chemical Co - Midland - MI 06

    Office of Legacy Management (LM)

    Midland - MI 06 FUSRAP Considered Sites Site: Dow Chemical Co. - Midland (MI.06 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Midland , Michigan MI.06-1 Evaluation Year: Circa 1987 MI.06-2 Site Operations: Conducted development work for production of magnesium-thorium alloys. MI.06-1 Site Disposition: Eliminated - AEC licensed site MI.06-1 MI.06-2 Radioactive Materials Handled: Yes Primary Radioactive Materials Handled:

  20. Coal Markets

    U.S. Energy Information Administration (EIA) Indexed Site

    Coal Markets | Archive Coal Markets Weekly production Dollars per short ton Dollars per mmbtu Average weekly coal commodity spot prices dollars per short ton Week ending Week ago change Central Appalachia 12,500 Btu, 1.2 SO2 Northern Appalachia 13,000 Btu, < 3.0 SO2 Illinois Basin 11,800 Btu, 5.0 SO2 Powder River Basin 8,800 Btu, 0.8 SO2 Uinta Basin 11,700 Btu, 0.8 SO2 Source: With permission, SNL Energy Note: Coal prices shown reflect those of relatively high-Btu coal selected in each region

  1. LBNL: Architecture 2030 District Program and Small Commercial...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Silicon Valley City of San Jose - San Jose, CA - Arizona State University - Phoenix, AZ - Emerging 2030 Districts - Ann Arbor, MI; Detroit, MI; San Antonio, TX; Ithaca, ...

  2. DOE - Office of Legacy Management -- General Motors Co - Flint - MI 07

    Office of Legacy Management (LM)

    Motors Co - Flint - MI 07 FUSRAP Considered Sites Site: GENERAL MOTORS CO. (MI.07 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: A.C. Spark Plug Dort Highway Plant MI.07-1 MI.07-2 Location: Flint , Michigan MI.07-1 Evaluation Year: 1987 MI.07-3 Site Operations: Processed thorium oxide, uranium oxide, and beryllium oxide into crucibles for the Chicago Area. MI.07-3 MI.07-4 MI.07-5 Site Disposition: Eliminated - Potential for contamination

  3. MINOS Experiment and NuMI Beam Home Page

    Broader source: All U.S. Department of Energy (DOE) Office Webpages

    NuMI-MINOS Neutrino Logo NuMI Beamline and MINOS Experiment Neutrino Logo The MINOS Experiment and NuMI Beamline Fermilab Logo MINOS Experiment Links ◊ MINOS for the Public ◊ Scientific Results ◊ MINOS at Work ◊ NuMI at Work ◊ MINOS+ Experiment Fermilab Neutrino Links ◊ Neutrino FAQ ◊ MINOS Underground Areas at Fermilab ◊ PPD Intensity Frontier Dept Back to - - - ◊ Fermilab at Work ◊ Fermilab Home the MINOS Far Detector in the Soudan Mine MINOS collaborators assembling the

  4. Magnetocrystalline anisotropy in <mi>UMn>2<mi>Ge>2 and related Mn-based actinide ferromagnets

    SciTech Connect (OSTI)

    Parker, David S.; Ghimire, Nirmal; Singleton, John; Thompson, J. D.; Bauer, Eric D.; Baumbach, Ryan; Mandrus, David; Li, Ling; Singh, David J.

    2015-05-04

    We present magnetization isotherms in pulsed magnetic fields up to 62 Tesla, supported by first principles calculations, demonstrating a huge uniaxial magnetocrystalline anisotropy energy - approximately 20 MJ/m3 - in <mi>UMn>2<mi>Ge>2. This large anisotropy results from the extremely strong spin-orbit coupling affecting the uranium 5 f electrons, which in the calculations exhibit a substantial orbital moment exceeding 2 μB. Finally, we also find from theoretical calculations that a number of isostructural Mn-actinide compounds are expected to have similarly large anisotropy.

  5. Petroleum Marketing Annual Archives

    U.S. Energy Information Administration (EIA) Indexed Site

    Petrolem Reports Petroleum Marketing Annual Archives The Petroleum Marketing Annual was discontinued in 2010. Choose the year from the archive Petroleum Marketing Annual you wish...

  6. Energy Imbalance Market Update

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    in CAISO Market Jim Price, Senior Advisor, Market Development & Analysis California ISO CAISO Public Market minimizes bid costs, while accounting for multiple transmission...

  7. Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells

    SciTech Connect (OSTI)

    Vrba, Lukas; Jensen, Taylor J.; Garbe, James C.; Heimark, Ronald L.; Cress, Anne E.; Dickinson, Sally; Stampfer, Martha R.; Futscher, Bernard W.

    2009-12-23

    BACKGROUND: The microRNA-200 family participates in the maintenance of an epithelial phenotype and loss of its expression can result in epithelial to mesenchymal transition (EMT). Furthermore, the loss of expression of miR-200 family members is linked to an aggressive cancer phenotype. Regulation of the miR-200 family expression in normal and cancer cells is not fully understood. METHODOLOGY/ PRINCIPAL FINDINGS: Epigenetic mechanisms participate in the control of miR-200c and miR-141 expression in both normal and cancer cells. A CpG island near the predicted mir-200c/mir-141 transcription start site shows a striking correlation between miR-200c and miR-141 expression and DNA methylation in both normal and cancer cells, as determined by MassARRAY technology. The CpG island is unmethylated in human miR-200/miR-141 expressing epithelial cells and in miR-200c/miR-141 positive tumor cells. The CpG island is heavily methylated in human miR-200c/miR-141 negative fibroblasts and miR-200c/miR-141 negative tumor cells. Mouse cells show a similar inverse correlation between DNA methylation and miR-200c expression. Enrichment of permissive histone modifications, H3 acetylation and H3K4 trimethylation, is seen in normal miR-200c/miR-141-positive epithelial cells, as determined by chromatin immunoprecipitation coupled to real-time PCR. In contrast, repressive H3K9 dimethylation marks are present in normal miR-200c/miR-141-negative fibroblasts and miR-200c/miR-141 negative cancer cells and the permissive histone modifications are absent. The epigenetic modifier drug, 5-aza-2'-deoxycytidine, reactivates miR-200c/miR-141 expression showing that epigenetic mechanisms play a functional role in their transcriptional control. CONCLUSIONS/ SIGNIFICANCE: We report that DNA methylation plays a role in the normal cell type-specific expression of miR-200c and miR-141 and this role appears evolutionarily conserved, since similar results were obtained in mouse. Aberrant DNA methylation of the

  8. miR-92a family and their target genes in tumorigenesis and metastasis

    SciTech Connect (OSTI)

    Li, Molin; Guan, Xingfang; Sun, Yuqiang; Mi, Jun; Shu, Xiaohong; Liu, Fang; Li, Chuangang

    2014-04-15

    The miR-92a family, including miR-25, miR-92a-1, miR-92a-2 and miR-363, arises from three different paralog clusters miR-17-92, miR-106a-363, and miR-106b-25 that are highly conservative in the process of evolution, and it was thought as a group of microRNAs (miRNAs) correlated with endothelial cells. Aberrant expression of miR-92a family was detected in multiple cancers, and the disturbance of miR-92a family was related with tumorigenesis and tumor development. In this review, the progress on the relationship between miR-92a family and their target genes and malignant tumors will be summarized. - Highlights: Aberrant expression of miR-92a, miR-25 and miR-363 can be observed in many kinds of malignant tumors. The expression of miR-92a family is regulated by LOH, epigenetic alteration, transcriptional factors such as SP1, MYC, E2F, wild-type p53 etc. Roles of miR-92a family in tumorigenesis and development: promoting cell proliferation, invasion and metastasis, inhibiting cell apoptosis.

  9. DOE - Office of Legacy Management -- Baker-Perkins Co - MI 13

    Office of Legacy Management (LM)

    Baker-Perkins Co - MI 13 FUSRAP Considered Sites Site: Baker-Perkins Co (MI 13) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Saginaw , Michigan MI.13-1 Evaluation Year: 1991 MI.13-1 MI.13-2 Site Operations: Small scale oxide mixing demonstrations and testing in May, 1956. MI.13-2 Site Disposition: Eliminated - Potential for contamination remote based on limited scope of activities at the site MI.13-3 Radioactive Materials Handled: Yes

  10. Sandia Energy - Solar Market Transformation

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Solar Market Transformation Home Stationary Power Energy Conversion Efficiency Solar Energy Photovoltaics Solar Market Transformation Solar Market TransformationTara...

  11. miR-17 inhibitor suppressed osteosarcoma tumor growth and metastasis via increasing PTEN expression

    SciTech Connect (OSTI)

    Gao, Yong; Luo, Ling-hui; Li, Shuai; Yang, Cao

    2014-02-07

    Highlights: • miR-17 was increased in OS tissues and cell lines. • Inhibition of miR-17 suppressed OS cell proliferation. • Inhibition of miR-17 suppressed OS cell migration and invasion. • PTEN was a target of miR-17. • miR-17 was negatively correlated with PTEN in OS tissues. - Abstract: MicroRNAs (miRNAs) play essential roles in cancer development and progression. Here, we investigated the role of miR-17 in the progression and metastasis of osteosarcoma (OS). miR-17 was frequently increased in OS tissues and cell lines. Inhibition of miR-17 in OS cell lines substantially suppressed cell proliferation, migration, and invasion. Phosphatase and tensin homolog (PTEN) was identified as a target of miR-17, and ectopic expression of miR-17 inhibited PTEN by direct binding to its 3′-untranslated region (3′-UTR). Expression of miR-17 was negatively correlated with PTEN in OS tissues. Together, these findings indicate that miR-17 acts as an oncogenic miRNA and may contribute to the progression and metastasis of OS, suggesting miR-17 as a potential novel diagnostic and therapeutic target of OS.

  12. Petroleum Marketing Annual 2009

    U.S. Energy Information Administration (EIA) Indexed Site

    Petroleum Marketing Annual 2009 Released: August 6, 2010 Next Release Date: Discontinued find annual data in Petroleum Marketing Monthly Monthly price and volume statistics on...

  13. Northwest Energy Market Assessment

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Northwest Energy Market Assessment Pages Northwest-Energy-Market-Assessment Sign In About | Careers | Contact | Investors | bpa.gov Search News & Us Expand News & Us Projects &...

  14. Petroleum Marketing Annual

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    PDF 1.2MB . Front Matter . Petroleum Marketing Annual Cover Page, Preface, and Table of Contents PDF . Highlights . Petroleum Marketing Annual Highlights PDF . . Summary Statistics ...

  15. Petroleum Marketing Annual

    Gasoline and Diesel Fuel Update (EIA)

    PDF 2.9MB . . Front Matter . Petroleum Marketing Annual Cover Page, Contacts, Preface, and Table of Contents PDF . . Highlights . Petroleum Marketing Annual Highlights PDF . . ...

  16. Petroleum Marketing Annual 1997

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    PDF 1.2MB . . Front Matter . Petroleum Marketing Annual Cover Page, Contacts, Preface, and Table of Contents PDF . . Highlights . Petroleum Marketing Annual Highlights PDF . . ...

  17. Demonstration & Market Transformation

    Broader source: Energy.gov (indexed) [DOE]

    Demonstration & Market Transformation Peer Review Break-Out Presentation Jim Spaeth Program Manager Demonstration & Market Transformation March 23, 2015 2 | Bioenergy Technologies ...

  18. Uranium Marketing Annual Report -

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    2. Maximum anticipated uranium market requirements of owners and operators of U.S. ... Source: U.S. Energy Information Administration: Form EIA-858 "Uranium Marketing Annual ...

  19. Diesel Engine Strategy & North American Market Challenges, Technology and Growth

    Broader source: Energy.gov [DOE]

    Presentation given at the 2007 Diesel Engine-Efficiency & Emissions Research Conference (DEER 2007). 13-16 August, 2007, Detroit, Michigan. Sponsored by the U.S. Department of Energy's (DOE) Office of FreedomCAR and Vehicle Technologies (OFCVT).

  20. MiR-218 Mediates tumorigenesis and metastasis: Perspectives and implications

    SciTech Connect (OSTI)

    Lu, Ying-fei; Zhang, Li; Waye, Mary Miu Yee; Fu, Wei-ming; Zhang, Jin-fang

    2015-05-15

    MicroRNAs (miRNAs) are a class of small non-coding RNAs that negatively regulate gene expression at the post-transcriptional level. As a highly conserved miRNA across a variety of species, microRNA-218 (miR-218) was found to play pivotal roles in tumorigenesis and progression. A group of evidence has demonstrated that miR-218 acts as a tumor suppressor by targeting many oncogenes related to proliferation, apoptosis and invasion. In this review, we provide a complex overview of miR-218, including its regulatory mechanisms, known functions in cancer and future challenges as a potential therapeutic target in human cancers. - Highlights: • miR-218 is frequently down regulated in multiple cancers. • miR-218 plays pivotal roles in carcinogenesis. • miR-218 mediates proliferation, apoptosis, metastasis, invasion, etc. • miR-218 mediates tumorigenesis and metastasis via multiple pathways.

  1. Petroleum Marketing Monthly

    U.S. Energy Information Administration (EIA) Indexed Site

    Crude oil prices U.S. Energy Information Administration | Petroleum Marketing Monthly 3 September 2016

  2. DOE - Office of Legacy Management -- Mitts-Merrill Co - MI 14

    Office of Legacy Management (LM)

    Mitts-Merrill Co - MI 14 FUSRAP Considered Sites Site: MITTS and MERRILL CO. (MI.14 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: Genessee Packing Co. MI.14-1 Location: Saginaw, Michigan MI.14-1 Evaluation Year: 1993 MI.14-2 Site Operations: Reduced thorium metal chunks into particle sized pieces on a small test scale during the mid-1950s. MI.14-1 Site Disposition: Eliminated - Potential for contamination considered remote based on limited quantity

  3. miRNA-205 affects infiltration and metastasis of breast cancer

    SciTech Connect (OSTI)

    Wang, Zhouquan; Department of Tumor, SenGong Hospital of Shaanxi, Xian 710300 ; Liao, Hehe; Deng, Zhiping; Yang, Po; Du, Ning; Zhanng, Yunfeng; Ren, Hong

    2013-11-08

    Highlights: We detected expression of miR-205 in breast cancer cell lines and tissue samples. We suggest miR-205 is downregulated in human breast cancer tissues and MCF7 cells. We suggest the lower expression of miR-205 play a role in breast cancer onset. These data suggest that miR-205 directly targets HER3 in human breast cancer. -- Abstract: Background: An increasing number of studies have shown that miRNAs are commonly deregulated in human malignancies, but little is known about the function of miRNA-205 (miR-205) in human breast cancer. The present study investigated the influence of miR-205 on breast cancer malignancy. Methods: The expression level of miR-205 in the MCF7 breast cancer cell line was determined by quantitative (q)RT-PCR. We then analyzed the expression of miR-205 in breast cancer and paired non-tumor tissues. Finally, the roles of miR-205 in regulating tumor proliferation, apoptosis, migration, and target gene expression were studied by MTT assay, flow cytometry, qRT-PCR, Western blotting and luciferase assay. Results: miR-205 was downregulated in breast cancer cells or tissues compared with normal breast cell lines or non-tumor tissues. Overexpression of miR-205 reduced the growth and colony-formation capacity of MCF7 cells by inducing apoptosis. Overexpression of miR-205 inhibited MCF7 cell migration and invasiveness. By bioinformation analysis, miR-205 was predicted to bind to the 3? untranslated regions of human epidermal growth factor receptor (HER)3 mRNA, and upregulation of miR-205 reduced HER3 protein expression. Conclusion: miR-205 is a tumor suppressor in human breast cancer by post-transcriptional inhibition of HER3 expression.

  4. NuMI Low Energy Flux Prediction Release

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NuMI Low Energy Flux Prediction Release Neutrino Flux Predictions for the NuMI Beam hep-ex/1607.00704 Data Ancillary data files for this result are available on arXiv at http://arxiv.org/src/1607.00704/anc.< /li> Among the available data files are: pdf file describing format of all the available files root file of all the available fluxes python code to read and process MINERvA's flux predictions Text Files of the flux, uncertainties, and covariance matrix, with units of neutrinos/m^2/POT,

  5. Port Huron, MI Liquefied Natural Gas Exports (Million Cubic Feet)

    U.S. Energy Information Administration (EIA) Indexed Site

    (Million Cubic Feet) Port Huron, MI Liquefied Natural Gas Exports (Million Cubic Feet) Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2013 1 2014 1 1 1 1 2 1 1 1 1 1 2015 1 1 1 1 1 - = No Data Reported; -- = Not Applicable; NA = Not Available; W = Withheld to avoid disclosure of individual company data. Release Date: 08/31/2016 Next Release Date: 09/30/2016 Referring Pages: U.S. Liquefied Natural Gas Exports by Point of Exit Port Huron, MI LNG Exports to All Countries

  6. Ground Motion Studies at NuMI

    SciTech Connect (OSTI)

    Mayda M. Velasco; Michal Szleper

    2012-02-20

    Ground motion can cause significant deterioration in the luminosity of a linear collider. Vibration of numerous focusing magnets causes continuous misalignments, which makes the beam emittance grow. For this reason, understanding the seismic vibration of all potential LC sites is essential and related efforts in many sites are ongoing. In this document we summarize the results from the studies specific to Fermilab grounds as requested by the LC project leader at FNAL, Shekhar Mishra in FY04-FY06. The Northwestern group focused on how the ground motion effects vary with depth. Knowledge of depth dependence of the seismic activity is needed in order to decide how deep the LC tunnel should be at sites like Fermilab. The measurements were made in the NuMI tunnel, see Figure 1. We take advantage of the fact that from the beginning to the end of the tunnel there is a height difference of about 350 ft and that there are about five different types of dolomite layers. The support received allowed to pay for three months of salary of Michal Szleper. During this period he worked a 100% of his time in this project. That include one week of preparation: 2.5 months of data taking and data analysis during the full period of the project in order to guarantee that we were recording high quality data. We extended our previous work and made more systematic measurements, which included detailed studies on stability of the vibration amplitudes at different depths over long periods of time. As a consequence, a better control and more efficient averaging out of the daytime variation effects were possible, and a better study of other time dependences before the actual depth dependence was obtained. Those initial measurements were made at the surface and are summarized in Figure 2. All measurements are made with equipment that we already had (two broadband seismometers KS200 from GEOTECH and DL-24 portable data recorder). The offline data analysis took advantage of the full Fourier spectra

  7. DOE - Office of Legacy Management -- Mitts-Merrel Co - MI 14

    Office of Legacy Management (LM)

    1993 MI.14-2 Site Operations: Reduced thorium metal chunks into particle sized pieces ... Primary Radioactive Materials Handled: Thorium MI.14-1 Radiological Survey(s): Yes - ...

  8. DOE - Office of Legacy Management -- Amex Specialty Metal Corp - MI 0-01

    Office of Legacy Management (LM)

    Amex Specialty Metal Corp - MI 0-01 FUSRAP Considered Sites Site: Amex Specialty Metal Corp (MI.0-01 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Coldwater , Michigan MI.0-01-1 Evaluation Year: 1987 MI.0-01-1 Site Operations: No indication that AMEX performed work for MED or AEC activities. Originally included on FUSRAP list due to fact that AMEX purchased milling equipment from a company that had done uranium milling.

  9. MiR-125a TNF receptor-associated factor 6 to inhibit osteoclastogenesis

    SciTech Connect (OSTI)

    Guo, Li-Juan; Liao, Lan; Yang, Li; Li, Yu; Jiang, Tie-Jian

    2014-02-15

    MicroRNAs (miRNAs) play important roles in osteoclastogenesis and bone resorption. In the present study, we found that miR-125a was dramatically down-regulated during macrophage colony stimulating factor (M-CSF) and receptor activator of nuclear factor-κB ligand (RANKL) induced osteoclastogenesis of circulating CD14+ peripheral blood mononuclear cells (PBMCs). Overexpression of miR-125a in CD14+ PBMCs inhibited osteoclastogenesis, while inhibition of miR-125a promoted osteoclastogenesis. TNF receptor-associated factor 6 (TRAF6), a transduction factor for RANKL/RANK/NFATc1 signal, was confirmed to be a target of miR-125a. EMSA and ChIP assays confirmed that NFATc1 bound to the promoter of the miR-125a. Overexpression of NFATc1 inhibited miR-125a transcription, and block of NFATc1 expression attenuated RANKL-regulated miR-125a transcription. Here, we reported that miR-125a played a biological function in osteoclastogenesis through a novel TRAF6/ NFATc1/miR-125a regulatory feedback loop. It suggests that regulation of miR-125a expression may be a potential strategy for ameliorating metabolic disease. - Highlights: • MiR-125a was significantly down-regulated in osteoclastogenesis of CD14+ PBMCs. • MiR-125a inhibited osteoclast differentiation by targeting TRAF6. • NFATc1 inhibited miR-125a transciption by binding to the promoter of miR-125a. • TRAF6/NFATc1 and miR-125a form a regulatory feedback loop in osteoclastogenesis.

  10. Clean Markets | Open Energy Information

    Open Energy Info (EERE)

    Markets Jump to: navigation, search Name: Clean Markets Place: Philadelphia, Pennsylvania Zip: 19118 Sector: Services Product: Philadelphia-based provider of market development...

  11. MiR-145 functions as a tumor suppressor targeting NUAK1 in human intrahepatic cholangiocarcinoma

    SciTech Connect (OSTI)

    Xiong, Xinkui; Sun, Daoyi; Chai, Hao; Shan, Wengang; Yu, Yue; Pu, Liyong; Cheng, Feng

    2015-09-18

    The dysregulation of micro (mi)RNAs is associated with cancer development. The miRNA miR-145 is downregulated in intrahepatic cholangiocarcinoma (ICC); however, its precise role in tumor progression has not yet been elucidated. Novel (nua) kinase family (NUAK)1 functions as an oncogene in various cancers and is a putative target of miR-145 regulation. In this study, we investigated the regulation of NUAK1 by miR-145 in ICC. We found that miR-145 level was significantly decreased in ICC tissue and cell lines, which corresponded with an increase in NUAK1 expression. NUAK1 was found to be a direct target of miR-145 regulation. The overexpression of miR-145 in ICC cell lines inhibited proliferation, growth, and invasion by suppressing NUAK1 expression, which was associated with a decrease in Akt signaling and matrix metalloproteinase protein expression. Similar results were observed by inhibiting NUAK1 expression. These results demonstrate that miR-145 can prevent ICC progression by targeting NUAK1 and its downstream effectors, and can therefore be useful for clinical diagnosis and targeted therapy of ICC. - Highlights: • MiR-145 suppresses ICC proliferation and invasion abilities. • We demonstrated that miR-145 directly targets NUAK1 in ICC. • MiR-145 expression in ICC was associated with Akt signaling and MMPs expression.

  12. Neutron scattering study of spin ordering and stripe pinning in superconducting <mi>La>1.93<mi>Sr>0.07<mi>CuO>4

    SciTech Connect (OSTI)

    Jacobsen, H.; Zaliznyak, I. A.; Savici, A. T.; Winn, B. L.; Chang, S.; Hücker, M.; Gu, G. D.; Tranquada, J. M.

    2015-11-20

    The relationships among charge order, spin fluctuations, and superconductivity in underdoped cuprates remain controversial. We use neutron scattering techniques to study these phenomena in <mi>La>1.93<mi>Sr>0.07<mi>CuO>4 a superconductor with a transition temperature of Tc = 20 K. At T<< Tc, we find incommensurate spin fluctuations with a quasielastic energy spectrum and no sign of a gap within the energy range from 0.2 to 15 meV. A weak elastic magnetic component grows below ~ 10 K, consistent with results from local probes. Regarding the atomic lattice, we have discovered unexpectedly strong fluctuations of the CuO6 octahedra about Cu-O bonds, which are associated with inequivalent O sites within the CuO2 planes. Moreover, we observed a weak elastic (3 30) superlattice peak that implies a reduced lattice symmetry. The presence of inequivalent O sites rationalizes various pieces of evidence for charge stripe order in underdoped La2-xSrxCuO4. The coexistence of superconductivity with quasi-static spin-stripe order suggests the presence of intertwined orders; however, the rotation of the stripe orientation away from the Cu-O bonds might be connected with evidence for a finite gap at the nodal points of the superconducting gap function.

  13. World Bio Markets

    Broader source: Energy.gov [DOE]

    Held in Amsterdam, Netherlands, the 10th anniversary World Bio Markets convened from March 1– 4, 2015.

  14. Radiosensitizing Effects of Ectopic miR-101 on Non-Small-Cell Lung Cancer Cells Depend on the Endogenous miR-101 Level

    SciTech Connect (OSTI)

    Chen, Susie; Wang Hongyan; Ng, Wooi Loon; Curran, Walter J.; Wang Ya

    2011-12-01

    Purpose: Previously, we showed that ectopic miR-101 could sensitize human tumor cells to radiation by targeting ATM and DNA-PK catalytic subunit (DNA-PKcs) to inhibit DNA repair, as the endogenous miR-101 levels are low in tumors in general. However, the heterogeneity of human cancers may result in an exception. The purpose of this study was to test the hypothesis that a few tumor cell lines with a high level of endogenous miR-101 would prove less response to ectopic miR-101. Methods and Materials: Fourteeen non-small-cell lung cancer (NSCLC) cell lines and one immortalized non-malignant lung epithelial cell line (NL20) were used for comparing endogenous miR-101 levels by real-time reverse transcription-polymerase chain reaction. Based on the different miR-101 levels, four cell lines with different miR-101 levels were chosen for transfection with a green fluorescent protein-lentiviral plasmid encoding miR-101. The target protein levels were measured by using Western blotting. The radiosensitizing effects of ectopic miR-101 on these NSCLC cell lines were determined by a clonogenic assay and xenograft mouse model. Results: The endogenous miR-101 level was similar or lower in 13 NSCLC cell lines but was 11-fold higher in one cell line (H157) than in NL20 cells. Although ectopic miR-101 efficiently decreased the ATM and DNA-PKcs levels and increased the radiosensitization level in H1299, H1975, and A549 cells, it did not change the levels of the miR-101 targets or radiosensitivity in H157 cells. Similar results were observed in xenograft mice. Conclusions: A small number of NSCLC cell lines could have a high level of endogenous miR-101. The ectopic miR-101 was able to radiosensitize most NSCLC cells, except for the NSCLC cell lines that had a much higher endogenous miR-101 level. These results suggest that when we choose one miRNA as a therapeutic tool, the endogenous level of the miRNA in each tumor should be considered.

  15. Market review - Market values summary/October market review/current market data

    SciTech Connect (OSTI)

    1995-11-01

    This article is the October 1995 uranium market summary. In this reporting period, there were four transactions in the natural uranium market, no activity in the spot UF6 market, no activity in the spot conversion market, and only a single activity in the enrichment services market. Spot uranium volume dropped sharply, and active uranium supply rose. The rise in demand, however, more than offset this increase. Unrestricted exchange prices rose slightly, as did the unrestricted UF6 value. All other prices remained steady.

  16. Technology-to-Market Initiative

    Broader source: Energy.gov [DOE]

    BTO’s Technology-to-Market (T2M) team drives high impact technologies from R&D to market readiness, preparing these technologies for real building demonstration, market deployment, and ultimately mass-market adoption.

  17. Development of HC-SCR System Using Diesel Fuel as a Reductant

    Broader source: Energy.gov [DOE]

    Poster presented at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  18. Advanced Diesel Combustion with Low Hydrocarbon and Carbon Monoxide Emissions

    Broader source: Energy.gov [DOE]

    Poster presented at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  19. New Developments in Titania-Based Catalysts for Selective Catalytic Reduction of NOx

    Broader source: Energy.gov [DOE]

    Presentation given at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  20. Slide 1

    Broader source: Energy.gov [DOE]

    Presentation given at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  1. An Analytical Approach for Tail-Pipe Emissions Estimation with...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    with Coupled Engine and Aftertreatment System Poster presented at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September ...

  2. Validation of a Small Engine Based Procedure for Studying Performance...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    for Engine Friction Reduction and Durable Design Poster presented at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September ...

  3. Heritage Garden | Open Energy Information

    Open Energy Info (EERE)

    Energy Developer Heritage Sustainable Energy Energy Purchaser Consumers Energy Detroit Edison Location Garden MI Coordinates 45.776334, -86.5527241 Show Map Loading...

  4. AVL Powertrain Engineering | Open Energy Information

    Open Energy Info (EERE)

    successadvisor.html AVL Powertrain Engineering is a company located in Detroit, MI. References "AVL" Retrieved from "http:en.openei.orgw...

  5. General Motors | Open Energy Information

    Open Energy Info (EERE)

    Motors Jump to: navigation, search Name: General Motors Place: Detroit, MI Website: www.generalmotors.com References: General Motors1 Information About Partnership with NREL...

  6. Slide Title

    Broader source: Energy.gov [DOE]

    Presentation given at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  7. Detection of Ammonia Slip Using NOx Sensor Signal Processing

    Broader source: Energy.gov [DOE]

    Presentation given at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  8. Development of a Thermal Enhancer ’ for Combined Partial Range Burning and Hydrocarbon Dosing

    Broader source: Energy.gov [DOE]

    Poster presented at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  9. Development of Urea Dosing System for 10 Liter Heavy Duty Diesel Engine Powered Vehicle

    Broader source: Energy.gov [DOE]

    Poster presented at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  10. Engine Waste Heat Recovery Concept Demonstration

    Broader source: Energy.gov [DOE]

    Poster presented at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  11. A Thermoelectric Generator with an Intermediate Heat Exchanger for Automotive Waste Heat Recovery System

    Broader source: Energy.gov [DOE]

    Poster presented at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  12. Evaluation of Variable Compression Ratio on Energy Efficiency

    Broader source: Energy.gov [DOE]

    Poster presented at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  13. Efficient Thermally Variable Cooling System

    Broader source: Energy.gov [DOE]

    Poster presented at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  14. Advantages of Oxygenates Fuels over Gasoline in Direct Injection Spark Ignition Engines

    Broader source: Energy.gov [DOE]

    Poster presented at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  15. Development of Optimal Catalyst Designs and Operating Strategies for Lean NOx Reduction in Coupled LNT-SCR Systems

    Broader source: Energy.gov [DOE]

    Poster presented at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  16. Development of an SI DI Ethanol Optimized Flex Fuel Engine Using Advanced Valvetrain

    Broader source: Energy.gov [DOE]

    Presentation given at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  17. Magnesium Replacement of Aluminum Cast Components in a Production V6 Engine to Effect Cost-Effective Mass Reduction

    Broader source: Energy.gov [DOE]

    Presentation given at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  18. Diesel Particulate Oxidation Model: Combined Effects of Fixed & Volatile Carbon

    Broader source: Energy.gov [DOE]

    Poster presented at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  19. Mr. Shaun Maloney :

    Office of Legacy Management (LM)

    ... Detroit, MI 48232 Chambersburg Engineering Co. Chambersburg, PA Ithaca Gun Co. Ithaca, NY New England Materials Lab., Inc. Teledyne Materials' . Medford, MA NRC Equipment Co. . -. ...

  20. Sources of UHC and CO in Low Temperature Automotive Diesel Combustion Systems

    Broader source: Energy.gov [DOE]

    Presentation given at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  1. Two in One: SCR on Filter

    Broader source: Energy.gov [DOE]

    Presentation given at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  2. Functionality of Commercial NOx Storage-Reduction Catalysts and the Development of a Representative Model

    Broader source: Energy.gov [DOE]

    Presentation given at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  3. Function Specific Analysis of the Thermal Durability of Cu-Zeolite SCR Catalyst

    Broader source: Energy.gov [DOE]

    Presentation given at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  4. Workbook Contents

    U.S. Energy Information Administration (EIA) Indexed Site

    ,"Worksheet Name","Description"," Of Series","Frequency","Latest Data for" ,"Data 1","Detroit, MI Natural Gas Pipeline Exports to Canada (MMcf)",1,"Annual",2014 ,"Release...

  5. Thermoelectric Generator Development for Automotive Waste Heat Recovery

    Broader source: Energy.gov [DOE]

    Presentation given at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  6. Modular Low Cost High Energy Exhaust Heat Thermoelectric Generator with Closed-Loop Exhaust By-Pass System

    Broader source: Energy.gov [DOE]

    Poster presented at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  7. A University Consortium on High Pressure, Lean Combustion for Efficient and Clean IC Engines (UM- lead, MIT, UCB)

    Office of Energy Efficiency and Renewable Energy (EERE)

    Presentation given at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  8. Performance of a High Speed Indirect Injection Diesel Engine with Poultry Fat Bio-Diesel

    Broader source: Energy.gov [DOE]

    Poster presented at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  9. Impact of Biodiesel Metals on the Performance and Durability of DOC and DPF Technologies

    Broader source: Energy.gov [DOE]

    Poster presented at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  10. Factors Impacting EGR Cooler Fouling- Main Effects and Interactions

    Broader source: Energy.gov [DOE]

    Presentation given at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  11. Improving Diesel Engine Sweet-spot Efficiency and Adapting it to Improve Duty-cycle MPG- plus Increasing Propulsion and Reducing Cost

    Office of Energy Efficiency and Renewable Energy (EERE)

    Poster presented at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  12. Thermoelectric Conversion of Wate Heat to Electricity in an IC Engine Powered Vehicle

    Broader source: Energy.gov [DOE]

    Presentation given at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  13. The Impact of Using Derived Fuel Consumption Maps to Predict Fuel Consumption

    Broader source: Energy.gov [DOE]

    Poster presented at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  14. Thermal Energy Storage Technology for Transportation and Other Applications D. Bank, M. Maurer, J. Penkala, K. Sehanobish, A. Soukhojak

    Broader source: Energy.gov [DOE]

    Poster presented at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  15. Load Expansion of Stoichiometric HCCI Using Spark Assist and Hydraulic Valve Actuation

    Broader source: Energy.gov [DOE]

    Presentation given at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  16. DTE | Open Energy Information

    Open Energy Info (EERE)

    Link to project description http:www.intelligentutility.comarticle1101energy-storage-nrel DTE is a company located in Detroit, MI. References "DTE Energy"...

  17. A Simple Approach of Tuning Catalytic Activity of MFI-Zeolites for Low-Temperature SCR of NOx

    Broader source: Energy.gov [DOE]

    Poster presented at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010.

  18. Improving the NOx-CO2 Trade-Off of an HCCI Engine using a Multi...

    Office of Scientific and Technical Information (OSTI)

    16-19, 2007 in Detroit, MI. Research Org: Sandia National Laboratories (SNL-CA), Livermore, CA (United States) Sponsoring Org: USDOE National Nuclear Security Administration ...

  19. World Bio Markets

    Broader source: Energy.gov [DOE]

    The World Bio Markets meeting will held from March 14-17, 2016 in Amsterdam, Netherlands. The meeting will gather experts in the bioenergy industry from all over the world. Bioenergy Technologies Office Demonstration and Market Transformation Program Manager Jim Spaeth will be giving a presentation entitled, “Policy updates and outlooks from key biofuel markets,” and will discuss technical, policy and investment developments, and success stories.

  20. Market place movements

    SciTech Connect (OSTI)

    1996-10-01

    Historical financial data is provided for the uranium market in graphical and tabular form. Data include uranium spot price range, spot conversion price range, and seperative work units price range. Additional spot market information provided is natural uranium by buyers and sellers. Medium- and long-term data includes average natural uranium prices, and natural uranium market by buyers and sellers. Information on US contracted supply and demand and uranium production in Australia, Canada, and the US is given.

  1. Agricultural Marketing Toolkit

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Agricultural-Marketing-Toolkit Sign In About | Careers | Contact | Investors | bpa.gov Search Policy & Reporting Expand Policy & Reporting EE Sectors Expand EE Sectors...

  2. BPA Marketing Portal

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    BPA-Marketing-Portal Sign In About | Careers | Contact | Investors | bpa.gov Search Policy & Reporting Expand Policy & Reporting EE Sectors Expand EE Sectors Technology &...

  3. Commercial Marketing Toolkit

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Commercial-Marketing-Toolkit Sign In About | Careers | Contact | Investors | bpa.gov Search Policy & Reporting Expand Policy & Reporting EE Sectors Expand EE Sectors Technology...

  4. 2013 Propane Market Outlook

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    domestic propane prices will not fully delink from oil prices, and competition against electricity and natural gas in traditional propane markets will remain very challenging....

  5. Navigant Market Report 2014

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    2014 Annual Market Assessment Prepared for: U.S. Department of Energy Client Contact Michael Hahn, Patrick Gilman Award Number DE-EE0005360 Navigant Consulting, Inc. 77 Bedford Street Suite 400 Burlington, MA 01803-5154 781.270.8314 www.navigant.com September 8, 2014 Offshore Wind Market and Economic Analysis Page ii Document Number DE-EE0005360 U.S. Offshore Wind Market and Economic Analysis 2014 Annual Market Assessment Document Number DE-EE0005360 Prepared for: U.S. Department of Energy

  6. Market Drivers for Biofuels

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    MARKET DRIVERS FOR BIOFUELS Brian Duff Chief Engineer Bioenergy Technologies Office 3 rd Annual MSW to Biofuels Summit, Orlando, FL February 20-21, 2013 2 | Bioenergy Technologies ...

  7. Market Acceleration (Fact Sheet)

    SciTech Connect (OSTI)

    Not Available

    2010-09-01

    The fact sheet summarizes the goals and activities of the DOE Solar Energy Technologies Program efforts within its market acceleration subprogram.

  8. One Market Plaza

    SciTech Connect (OSTI)

    2010-04-01

    This is a combined heat and power (CHP) project profile on a 1.5 MW CHP system at One Market Plaza in San Francisco, California.

  9. Petroleum Marketing Monthly

    U.S. Energy Information Administration (EIA) Indexed Site

    U.S. Refi ner retail petroleum product prices U.S. Energy Information Administration | Petroleum Marketing Monthly 7 September 2016

  10. Petroleum Marketing Monthly

    U.S. Energy Information Administration (EIA) Indexed Site

    U.S. Refi ner retail petroleum product volumes U.S. Energy Information Administration | Petroleum Marketing Monthly 9 September 2016

  11. Petroleum Marketing Monthly

    U.S. Energy Information Administration (EIA) Indexed Site

    U.S. Refi ner wholesale petroleum product volumes U.S. Energy Information Administration | Petroleum Marketing Monthly 13 September 20

  12. Energy Markets 201

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    etc.) * Volume (MWshr) * Term (hourly, daily, monthly, quarterly, etc.) * Trading hub (Mead230, Palo Verde, etc.) How are prices set? * Market prices are determined by ...

  13. Orchestrating Market Success: Seattle Market Introduction Workshop Video |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Orchestrating Market Success: Seattle Market Introduction Workshop Video Orchestrating Market Success: Seattle Market Introduction Workshop Video View the video from Jim Brodrick's opening presentation at the July 2011 DOE SSL Market Introduction Workshop in Seattle, Washington

  14. Deployment & Market Transformation (Brochure)

    SciTech Connect (OSTI)

    Not Available

    2012-04-01

    NREL's deployment and market transformation (D and MT) activities encompass the laboratory's full range of technologies, which span the energy efficiency and renewable energy spectrum. NREL staff educates partners on how they can advance sustainable energy applications and also provides clients with best practices for reducing barriers to innovation and market transformation.

  15. Marketing Transformation (Fact Sheet)

    SciTech Connect (OSTI)

    DOE Solar Energy Technologies Program

    2011-10-13

    Through the SunShot Initiative, the U.S. Department of Energy (DOE) works with manufacturers, communities, states, utilities, and other partners to enable the solar market by reducing non-hardware balance-of-system (BOS) costs, developing a skilled workforce, and eliminating market barriers to widespread adoption of solar technologies.

  16. 200 Market Building

    High Performance Buildings Database

    Portland, Oregon The 200 Market Building is a high-rise built in 1973 and located in downtown Portland, Oregon. It was purchased in 1988 by its current owner, 200 Market Associates, primarily because of its optimal location in Portland's central business district. Since 1989 the building has undergone continuous improvements in multiple phases.

  17. Sandia Energy - Past Market Transformation Activities

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Past Market Transformation Activities Home Stationary Power Energy Conversion Efficiency Solar Energy Photovoltaics Solar Market Transformation Past Market Transformation...

  18. DLEU2, frequently deleted in malignancy, functions as a critical host gene of the cell cycle inhibitory microRNAs miR-15a and miR-16-1

    SciTech Connect (OSTI)

    Lerner, Mikael; Harada, Masako; Loven, Jakob; Castro, Juan; Davis, Zadie; Oscier, David; Henriksson, Marie; Sangfelt, Olle; Grander, Dan; Corcoran, Martin M.

    2009-10-15

    The microRNAs miR-15a and miR-16-1 are downregulated in multiple tumor types and are frequently deleted in chronic lymphocytic leukemia (CLL), myeloma and mantle cell lymphoma. Despite their abundance in most cells the transcriptional regulation of miR-15a/16-1 remains unclear. Here we demonstrate that the putative tumor suppressor DLEU2 acts as a host gene of these microRNAs. Mature miR-15a/miR-16-1 are produced in a Drosha-dependent process from DLEU2 and binding of the Myc oncoprotein to two alterative DLEU2 promoters represses both the host gene transcript and levels of mature miR-15a/miR-16-1. In line with a functional role for DLEU2 in the expression of the microRNAs, the miR-15a/miR-16-1 locus is retained in four CLL cases that delete both promoters of this gene and expression analysis indicates that this leads to functional loss of mature miR-15a/16-1. We additionally show that DLEU2 negatively regulates the G1 Cyclins E1 and D1 through miR-15a/miR-16-1 and provide evidence that these oncoproteins are subject to miR-15a/miR-16-1-mediated repression under normal conditions. We also demonstrate that DLEU2 overexpression blocks cellular proliferation and inhibits the colony-forming ability of tumor cell lines in a miR-15a/miR-16-1-dependent way. Together the data illuminate how inactivation of DLEU2 promotes cell proliferation and tumor progression through functional loss of miR-15a/miR-16-1.

  19. Genome-Wide Analysis of miRNA targets in Brachypodium and Biomass Energy Crops

    SciTech Connect (OSTI)

    Green, Pamela J.

    2015-08-11

    MicroRNAs (miRNAs) contribute to the control of numerous biological processes through the regulation of specific target mRNAs. Although the identities of these targets are essential to elucidate miRNA function, the targets are much more difficult to identify than the small RNAs themselves. Before this work, we pioneered the genome-wide identification of the targets of Arabidopsis miRNAs using an approach called PARE (German et al., Nature Biotech. 2008; Nature Protocols, 2009). Under this project, we applied PARE to Brachypodium distachyon (Brachypodium), a model plant in the Poaceae family, which includes the major food grain and bioenergy crops. Through in-depth global analysis and examination of specific examples, this research greatly expanded our knowledge of miRNAs and target RNAs of Brachypodium. New regulation in response to environmental stress or tissue type was found, and many new miRNAs were discovered. More than 260 targets of new and known miRNAs with PARE sequences at the precise sites of miRNA-guided cleavage were identified and characterized. Combining PARE data with the small RNA data also identified the miRNAs responsible for initiating approximately 500 phased loci, including one of the novel miRNAs. PARE analysis also revealed that differentially expressed miRNAs in the same family guide specific target RNA cleavage in a correspondingly tissue-preferential manner. The project included generation of small RNA and PARE resources for bioenergy crops, to facilitate ongoing discovery of conserved miRNA-target RNA regulation. By associating specific miRNA-target RNA pairs with known physiological functions, the research provides insights about gene regulation in different tissues and in response to environmental stress. This, and release of new PARE and small RNA data sets should contribute basic knowledge to enhance breeding and may suggest new strategies for improvement of biomass energy crops.

  20. Interaction Between Carbon Markets and Renewable Energy Markets (Poster)

    SciTech Connect (OSTI)

    Carroll, G. L.; Milford, J.; Bird, L.

    2006-10-03

    This poster, submitted for the CU Energy Initiative/NREL Symposium on October 3, 2006 in Boulder, Colorado, discusses the interaction between carbon markets and renewable energy markets.

  1. Creating Market Pathways for Laboratory Research

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    eere/technology-to-market/lab-corps

  2. miR-4295 promotes cell proliferation and invasion in anaplastic thyroid carcinoma via CDKN1A

    SciTech Connect (OSTI)

    Shao, Mingchen; Geng, Yiwei; Lu, Peng; Xi, Ying; Wei, Sidong; Wang, Liuxing; Fan, Qingxia; Ma, Wang

    2015-09-04

    MicroRNAs (miRNAs) play important roles in the pathogenesis of many types of cancers by negatively regulating gene expression at posttranscriptional level. However, the role of microRNAs in anaplastic thyroid carcinoma (ATC), has remained elusive. Here, we identified that miR-4295 promotes ATC cell proliferation by negatively regulates its target gene CDKN1A. In ATC cell lines, CCK-8 proliferation assay indicated that the cell proliferation was promoted by miR-4295, while miR-4295 inhibitor significantly inhibited the cell proliferation. Transwell assay showed that miR-4295 mimics significantly promoted the migration and invasion of ATC cells, whereas miR-4295 inhibitors significantly reduced cell migration and invasion. luciferase assays confirmed that miR-4295 directly bound to the 3'untranslated region of CDKN1A, and western blotting showed that miR-4295 suppressed the expression of CDKN1A at the protein levels. This study indicated that miR-4295 negatively regulates CDKN1A and promotes proliferation and invasion of ATC cell lines. Thus, miR-4295 may represent a potential therapeutic target for ATC intervention. - Highlights: • miR-4295 mimics promote the proliferation and invasion of ATC cells. • miR-4295 inhibitors inhibit the proliferation and invasion of ATC cells. • miR-4295 targets 3′UTR of CDKN1A in ATC cells. • miR-4295 negatively regulates CDKN1A in ATC cells.

  3. Microfluidic Molecular Assay Platform for the Detection of miRNAs...

    Office of Scientific and Technical Information (OSTI)

    Article: Microfluidic Molecular Assay Platform for the Detection of miRNAs, mRNAs, Proteins, and Post-translational Modifications at Single-cell Resolution. Citation Details...

  4. Groundwater protection for the NuMI project

    SciTech Connect (OSTI)

    Wehmann, A.; Smart, W.; Menary, S.; Hylen, J.; Childress, S.

    1997-10-01

    The physics requirements for the long base line neutrino oscillation experiment MINOS dictate that the NuMI beamline be located in the aquifer at Fermilab. A methodology is described for calculating the level of radioactivation of groundwater caused by operation of this beamline. A conceptual shielding design for the 750 meter long decay pipe is investigated which would reduce radioactivation of the groundwater to below government standards. More economical shielding designs to meet these requirements are being explored. Also, information on local geology, hydrogeology, government standards, and a glossary have been included.

  5. 2015 Uranium Marketing Annual Report

    U.S. Energy Information Administration (EIA) Indexed Site

    1 2015 Uranium Marketing Annual Report Release Date: May 24, 2016 Next Release Date: May ... Source: U.S. Energy Information Administration, Form EIA-858 "Uranium Marketing Annual ...

  6. 2015 Uranium Marketing Annual Report

    U.S. Energy Information Administration (EIA) Indexed Site

    U.S. Energy Information Administration 2015 Uranium Marketing Annual Report 2015 Uranium Marketing Annual Report Release Date: May 24, 2016 Next Release Date: May 2017 Minimum ...

  7. 2015 Uranium Marketing Annual Report

    U.S. Energy Information Administration (EIA) Indexed Site

    U.S. Energy Information Administration 2015 Uranium Marketing Annual Report 2015 Uranium Marketing Annual Report Release Date: May 24, 2016 Next Release Date: May 2017 Origin of ...

  8. 2015 Uranium Marketing Annual Report

    U.S. Energy Information Administration (EIA) Indexed Site

    7 2015 Uranium Marketing Annual Report Release Date: May 24, 2016 Next Release Date: May ... Source: U.S. Energy Information Administration, Form EIA-858 "Uranium Marketing Annual ...

  9. 2015 Uranium Marketing Annual Report

    U.S. Energy Information Administration (EIA) Indexed Site

    3 2015 Uranium Marketing Annual Report Release Date: May 24, 2016 Next Release Date: May ... Source: U.S. Energy Information Administration: Form EIA-858 "Uranium Marketing Annual ...

  10. 2015 Uranium Marketing Annual Report

    U.S. Energy Information Administration (EIA) Indexed Site

    9 2015 Uranium Marketing Annual Report Release Date: May 24, 2016 Next Release Date: May ... Source: U.S. Energy Information Administration, Form EIA-858 "Uranium Marketing Annual ...

  11. 2011 Wind Technologies Market Report

    SciTech Connect (OSTI)

    Wiser, R.; Bolinger, M.

    2012-08-01

    This report describes the status of the U.S. wind energy industry market in 2011; its trends, performance, market drivers and future outlook.

  12. 2012 Wind Technologies Market Report

    SciTech Connect (OSTI)

    Wiser, R.; Bolinger, M.; Barbose, G.; Darghouth, N.; Hoen, B.; Mills, A.; Weaver, S.; Porter, K.; Buckley, M.; Fink, S.; Oteri, F.; Tegen, S.

    2013-08-01

    This report describes the status of the U.S. wind energy industry market in 2012; its trends, performance, market drivers and future outlook.

  13. 2010 Wind Technologies Market Report

    SciTech Connect (OSTI)

    Wiser, R.; Bolinger, M.

    2011-06-01

    This report describes the status of the U.S. wind energy industry market in 2010; its trends, performance, market drivers and future outlook.

  14. 2013 Wind Technologies Market Report

    SciTech Connect (OSTI)

    Wiser, Ryan; Bolinger, Mark

    2014-08-15

    This report describes the status of the U.S. wind energy industry market in 2013; its trends, performance, market drivers and future outlook.

  15. Energy Management and Marketing Specialist

    Broader source: Energy.gov [DOE]

    (See Frequently Asked Questions for more information). Where would I be working? Western Area Power Administration, Upper Great Plains Region (UGP), Power Marketing, Energy Management and Marketing...

  16. 2015 Uranium Marketing Annual Report

    U.S. Energy Information Administration (EIA) Indexed Site

    Uranium Marketing Annual Report 2015 Uranium Marketing Annual Report Release Date: May 24, 2016 Next Release Date: May 2017 Number of purchasers Quantity with reported price ...

  17. Opportunity Assessment Clean Diesels in the North American Light Duty Market

    Broader source: Energy.gov [DOE]

    Presentation given at the 2007 Diesel Engine-Efficiency & Emissions Research Conference (DEER 2007). 13-16 August, 2007, Detroit, Michigan. Sponsored by the U.S. Department of Energy's (DOE) Office of FreedomCAR and Vehicle Technologies (OFCVT).

  18. Why Light Duty Diesels Make Sense in the North American Market

    Broader source: Energy.gov [DOE]

    Presentation given at DEER 2006, August 20-24, 2006, Detroit, Michigan. Sponsored by the U.S. DOE's EERE FreedomCar and Fuel Partnership and 21st Century Truck Programs.

  19. Accelerating Light-Duty Diesel Sales in the U.S. Market

    Office of Energy Efficiency and Renewable Energy (EERE)

    Presentation given at DEER 2006, August 20-24, 2006, Detroit, Michigan. Sponsored by the U.S. DOE's EERE FreedomCar and Fuel Partnership and 21st Century Truck Programs.

  20. Petroleum Marketing Annual

    U.S. Energy Information Administration (EIA) Indexed Site

    8 Entire . The entire report as a single file. PDF 1.2MB . Front Matter . Petroleum Marketing Annual Cover Page, Preface, and Table of Contents PDF . Highlights . Petroleum...

  1. Petroleum Marketing Annual

    U.S. Energy Information Administration (EIA) Indexed Site

    5 Entire . The entire report as a single file. PDF 2.9MB . . Front Matter . Petroleum Marketing Annual Cover Page, Contacts, Preface, and Table of Contents PDF . . Highlights ....

  2. Petroleum Marketing Annual 2009

    U.S. Energy Information Administration (EIA) Indexed Site

    cents per gallon to dollars per gallon later this year for the 2010 data. Petroleum Marketing Annual --- Full report in PDF (1.2 MB) Summary Statistics Summary Statistics Tables...

  3. Petroleum Marketing Annual 2008

    U.S. Energy Information Administration (EIA) Indexed Site

    8 Released: August 27, 2009 Petroleum Marketing Annual --- Full report in PDF (1.2 MB) Summary Statistics Summary Statistics Tables PDF 1 Crude Oil Prices PDF TXT 1A Refiner...

  4. Petroleum Marketing Annual 1997

    U.S. Energy Information Administration (EIA) Indexed Site

    7 Entire . The entire report as a single file. PDF 1.2MB . . Front Matter . Petroleum Marketing Annual Cover Page, Contacts, Preface, and Table of Contents PDF . . Highlights ....

  5. Petroleum Marketing Annual

    U.S. Energy Information Administration (EIA) Indexed Site

    6 Entire . The entire report as a single file. PDF 2.9MB . . Front Matter . Petroleum Marketing Annual Cover Page, Contacts, Preface, and Table of Contents PDF . . Highlights ....

  6. Petroleum Marketing Annual 2007

    U.S. Energy Information Administration (EIA) Indexed Site

    7 Released: August 29, 2008 Petroleum Marketing Annual --- Full report in PDF (1.2 MB) Summary Statistics Summary Statistics Tables PDF 1 Crude Oil Prices PDF TXT 1A Refiner...

  7. Petroleum Marketing Annual

    U.S. Energy Information Administration (EIA) Indexed Site

    9 Entire . The entire report as a single file. PDF 1.2MB . Front Matter . Petroleum Marketing Annual Cover Page, Preface, and Table of Contents PDF . Highlights . Petroleum...

  8. Stimulate the Market

    Broader source: Energy.gov [DOE]

    After a technology has passed though the High Impact Technology (HIT) prioritization process, DOE works with a range of partners to select and push forward specific market transformation strategies.

  9. Energy Market Outlook

    Office of Energy Efficiency and Renewable Energy (EERE)

    Presentation covers the Federal Utility Partnership Working Group Energy Market Outlook: Helping Customers Meet Their Diverse Energy Goals, held on May 22-23, 2013 in San Francisco, California.

  10. Delineating coal market regions

    SciTech Connect (OSTI)

    Solomon, B.D.; Pyrdol, J.J.

    1986-04-01

    This study addresses the delineation of US coal market regions and their evolution since the 1973 Arab oil embargo. Dichotomizing into compliance (low sulfur) and high sulfur coal deliveries, market regions are generated for 1973, 1977, and 1983. Focus is restricted to steam coal shipments to electric utilities, which currently account for over 80% of the total domestic market. A two-stage method is used. First, cluster analyses are performed on the origin-destination shipments data to generate baseline regions. This is followed by multiple regression analyses on CIF delivered price data for 1983. Sensitivity analysis on the configuration of the regions is also conducted, and some thoughts on the behavior of coal markets conclude the paper. 37 references, 6 figures, 2 tables.

  11. Coal markets squeeze producers

    SciTech Connect (OSTI)

    Ryan, M.

    2005-12-01

    Supply/demand fundamentals seem poised to keep prices of competing fossil fuels high, which could cushion coal prices, but increased mining and transportation costs may squeeze producer profits. Are markets ready for more volatility?

  12. Petroleum marketing annual 1994

    SciTech Connect (OSTI)

    1995-08-24

    The Petroleum Marketing Annual (PMA) provides information and statistical data on a variety of crude oils and refined petroleum products. The publication presents statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysis, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the fob and landed cost of imported crude oil, and the refiners` acquisition cost of crude oil. Refined petroleum product sales data include motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane. The Petroleum Marketing Division, Office of Oil and Gas, Energy Information Administration ensures the accuracy, quality, and confidentiality of the published data in the Petroleum Marketing Annual. For this production, all estimates have been recalculated since their earlier publication in the Petroleum Marketing Monthly (PMM). These calculations made use of additional data and corrections that were received after the PMM publication date.

  13. Solar Market Pathways

    Broader source: Energy.gov [DOE]

    The Solar Market Pathways website distributes key insights from 15 SunShot Initiative projects that are advancing solar deployment across the United States. These projects take a variety of...

  14. Uranium Marketing Annual Report -

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    5. Shipments of uranium feed by owners and operators of U.S. civilian nuclear power ... Source: U.S. Energy Information Administration: Form EIA-858 "Uranium Marketing Annual ...

  15. Uranium Marketing Annual Report -

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    0. Contracted purchases of uranium from suppliers by owners and operators of U.S. civilian ... Source: U.S. Energy Information Administration, Form EIA-858 "Uranium Marketing Annual ...

  16. Demonstration & Market Transformation

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Demonstration & Market Transformation Peer Review Break-Out Presentation Jim Spaeth Program Manager Demonstration & Market Transformation March 23, 2015 2 | Bioenergy Technologies Office DMT Portfolio Peer Review * Introduction of the DMT Peer Review Team * Peer Review Process - Ground rules for review process * DMT Approach to Project Management - Budget Periods * Changes Made in Response to the 2013 Peer Review - Lessons Learned / Best Practices * Portfolio Overview - FOA Status and

  17. Forward capacity market CONEfusion

    SciTech Connect (OSTI)

    Wilson, James F.

    2010-11-15

    In ISO New England and PJM it was assumed that sponsors of new capacity projects would offer them into the newly established forward centralized capacity markets at prices based on their levelized net cost of new entry, or ''Net CONE.'' But the FCCMs have not operated in the way their proponents had expected. To clear up the CONEfusion, FCCM designs should be reconsidered to adapt them to the changing circumstances and to be grounded in realistic expectations of market conduct. (author)

  18. Oil-futures markets

    SciTech Connect (OSTI)

    Prast, W.G.; Lax, H.L.

    1983-01-01

    This book on oil futures trading takes a look at a market and its various hedging strategies. Growing interest in trading of commodity futures has spread to petroleum, including crude oil, and key refined products such as gasoline and heating oil. This book describes how the international petroleum trade is structured, examines the working of oil futures markets in the United States and the United Kingdom, and assesses the possible courses of further developments.

  19. Market review - market values summary/February market review/current market data

    SciTech Connect (OSTI)

    1996-03-01

    This article is the February 1996 uranium market report. As reflected by the rising demand and decreasing supply of uranium, prices for UF6 and U3O8 increased. Separation services and conversion services prices remained constant. Data is presented for the recent trades, blocks or uranium for sale or loan, inquiries to purchase or borrow uranium, SWUs available and inquiries to purchase SWUs, and market values of U3O8 and UF6 expressed in selected currencies.

  20. miR-129 suppresses tumor cell growth and invasion by targeting PAK5 in hepatocellular carcinoma

    SciTech Connect (OSTI)

    Zhai, Jian; Qu, Shuping; Li, Xiaowei; Zhong, Jiaming; Chen, Xiaoxia; Qu, Zengqiang; Wu, Dong

    2015-08-14

    Emerging evidence suggests that microRNAs (miRNAs) play important roles in regulating HCC development and progression; however, the mechanisms by which their specific functions and mechanisms remained to be further explored. miR-129 has been reported in gastric cancers, lung cancer and colon cancer. In this study, we disclosed a new tumor suppresser function of miR-129 in HCC. We also found the downregulation of miR-129 occurred in nearly 3/4 of the tumors examined (56/76) compared with adjacent nontumorous tissues, which was more importantly, correlated to the advanced stage and vascular invasion. We then demonstrated that miR-129 overexpression attenuated HCC cells proliferation and invasion, inducing apoptosis in vitro. Moreover, we used miR-129 antagonist and found that anti-miR-129 promoted HCC cells malignant phenotypes. Mechanistically, our further investigations revealed that miR-129 suppressed cell proliferation and invasion by targeting the 3’-untranslated region of PAK5, as well as miR-129 silencing up-regulated PAK5 expression. Moreover, miR-129 expression was inversely correlated with PAK5 expression in 76 cases of HCC samples. RNA interference of PAK5 attenuated anti-miR-129 mediated cell proliferation and invasion in HCC cells. Taken together, these results demonstrated that miR-129 suppressed tumorigenesis and progression by directly targeting PAK5, defining miR-129 as a potential treatment target for HCC. - Highlights: • Decreased of miR-129 is found in HCC and associated with advanced stage and metastasis. • miR-129 suppresses proliferation and invasion of HCC cells. • miR-129 directly targets the 3′ UTR of PAK5 and diminishes PAK5 expression. • PAK5 is involved in miR-129 mediated suppression functions.

  1. MiR-153 inhibits migration and invasion of human non-small-cell lung cancer by targeting ADAM19

    SciTech Connect (OSTI)

    Shan, Nianxi; Shen, Liangfang; Wang, Jun; He, Dan; Duan, Chaojun

    2015-01-02

    Highlights: • Decreased miR-153 and up-regulated ADAM19 are correlated with NSCLC pathology. • MiR-153 inhibits the proliferation and migration and invasion of NSCLC cells in vitro. • ADAM19 is a direct target of miR-153. • ADAM19 is involved in miR-153-suppressed migration and invasion of NSCLC cells. - Abstract: MiR-153 was reported to be dysregulated in some human cancers. However, the function and mechanism of miR-153 in lung cancer cells remains unknown. In this study, we investigated the role of miR-153 in human non-small-cell lung cancer (NSCLC). Using qRT-PCR, we demonstrated that miR-153 was significantly decreased in clinical NSCLC tissues and cell lines, and downregulation of miR-153 was significantly correlated with lymph node status. We further found that ectopic expression of miR-153 significantly inhibited the proliferation and migration and invasion of NSCLC cells in vitro, suggesting that miR-153 may be a novel tumor suppressor in NSCLC. Further integrated analysis revealed that ADAM19 is as a direct and functional target of miR-153. Luciferase reporter assay demonstrated that miR-153 directly targeted 3′UTR of ADAM19, and correlation analysis revealed an inverse correlation between miR-153 and ADAM19 mRNA levels in clinical NSCLC tissues. Knockdown of ADAM19 inhibited migration and invasion of NSCLC cells which was similar with effects of overexpression of miR-153, while overexpression of ADAM19 attenuated the function of miR-153 in NSCLC cells. Taken together, our results highlight the significance of miR-153 and ADAM19 in the development and progression of NSCLC.

  2. Transcriptional regulation of miR-146b by C/EBPβ LAP2 in esophageal cancer cells

    SciTech Connect (OSTI)

    Li, Junxia; Shan, Fabo; Xiong, Gang; Wang, Ju-Ming; Wang, Wen-Lin; Xu, Xueqing; Bai, Yun

    2014-03-28

    Highlights: • MiR-146b promotes esophageal cancer cell proliferation. • MiR-146b inhibits esophageal cancer cell apoptosis. • C/EBPβ directly binds to miR-146b promoter conserved region. • MiR-146b is up-regulated by C/EBPβ LAP2 transcriptional activation. - Abstract: Recent clinical study indicated that up-regulation of miR-146b was associated with poor overall survival of patients in esophageal squamous cell carcinoma. However, the underlying mechanism of miR-146b dysregulation remains to be explored. Here we report that miR-146b promotes cell proliferation and inhibits cell apoptosis in esophageal cancer cell lines. Mechanismly, two C/EBPβ binding motifs are located in the miR-146b promoter conserved region. Among the three isoforms of C/EBPβ, C/EBPβ LAP2 positively regulated miR-146b expression and increases miR-146b levels in a dose-dependent manner through transcription activation of miR-146b gene. Together, these results suggest a miR-146b regulatory mechanism involving C/EBPβ, which may contribute to the up-regulation of miR-146b in esophageal squamous cell carcinoma.

  3. 2010 Solar Technologies Market Report

    SciTech Connect (OSTI)

    Not Available

    2011-11-01

    The U.S. Department of Energy (DOE) 2010 Solar Technologies Market Report details the market conditions and trends for photovoltaic (PV) and concentrating solar power (CSP) technologies. Produced by the National Renewable Energy Laboratory (NREL), the report provides a comprehensive overview of the solar electricity market and identifies successes and trends within the market from both global and national perspectives.

  4. miR-30a suppresses breast cancer cell proliferation and migration by targeting Eya2

    SciTech Connect (OSTI)

    Fu, Jing; Xu, Xiaojie; Kang, Lei; Zhou, Liying; Wang, Shibin; Lu, Juming; Cheng, Long; Fan, Zhongyi; Yuan, Bin; Tian, Peirong; Zheng, Xiaofei; Yu, Chengze; Ye, Qinong; Lv, Zhaohui

    2014-03-07

    Highlights: • miR-30a represses Eya2 expression by binding to the 3′-untranslated region of Eya2. • The miR-30a/EYA2 axis regulates breast cancer cell proliferation and migration. • The miR-30a/EYA2 axis modulates G1/S cell cycle progression. • The miR-30a/EYA2 axis is dysregulated in breast cancer patients. - Abstract: Eye absent (Eya) proteins are involved in cell fate determination in a broad spectrum of cells and tissues. Aberrant expression of Eya2 has been documented in a variety of cancers and correlates with clinical outcome. However, whether microRNAs (miRNAs) can regulate Eya2 expression remains unknown. Here, we show that miR-30a represses Eya2 expression by binding to the 3′-untranslated region of Eya2. Overexpression of Eya2 in miR-30a-transfected breast cancer cells effectively rescued the inhibition of cell proliferation and migration caused by miR-30a. Knockdown of Eya2 by small-interfering RNA (siRNA) in breast cancer cells mimicked the effect induced by miR-30a and abolished the ability of miR-30a to regulate breast cancer cell proliferation and migration. The miR-30a/Eya2 axis could regulate G1/S cell cycle progression, accompanied by the modulation of expression of cell cycle-related proteins, including cyclin A, cyclin D1, cyclin E, and c-Myc. Moreover, miR-30a expression was downregulated in breast cancer patients, and negatively correlated with Eya2, which was upregulated in breast cancer patients. These data suggest that the miR-30a/Eya2 axis may play an important role in breast cancer development and progression and that miR-30a activation or Eya2 inhibition may be a useful strategy for cancer treatment.

  5. miR-92a is upregulated in cervical cancer and promotes cell proliferation and invasion by targeting FBXW7

    SciTech Connect (OSTI)

    Zhou, Chuanyi; Shen, Liangfang; Mao, Lei; Wang, Bing; Li, Yang; Yu, Huizhi

    2015-02-27

    MicroRNAs (miRNAs) are involved in the cervical carcinogenesis and progression. In this study, we investigated the role of miR-92a in progression and invasion of cervical cancer. MiR-92a was significantly upregulated in cervical cancer tissues and cell lines. Overexpression of miR-92a led to remarkably enhanced proliferation by promoting cell cycle transition from G1 to S phase and significantly enhanced invasion of cervical cancer cells, while its knockdown significantly reversed these cellular events. Bioinformatics analysis suggested F-box and WD repeat domain-containing 7 (FBXW7) as a novel target of miR-92a, and miR-92a suppressed the expression level of FBXW7 mRNA by direct binding to its 3′-untranslated region (3′UTR). Expression of miR-92a was negatively correlated with FBXW7 in cervical cancer tissues. Furthermore, Silencing of FBXW7 counteracted the effects of miR-92a suppression, while its overexpression reversed oncogenic effects of miR-92a. Together, these findings indicate that miR-92a acts as an onco-miRNA and may contribute to the progression and invasion of cervical cancer, suggesting miR-92a as a potential novel diagnostic and therapeutic target of cervical cancer. - Highlights: • miR-92a is elevated in cervical cancer tissues and cell lines. • miR-92a promotes cervical cancer cell proliferation, cell cycle transition from G1 to S phase and invasion. • FBXW7 is a direct target of miR-92a. • FBXW7 counteracts the oncogenic effects of miR-92a on cervical cancer cells.

  6. Market Analyses | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Combined Heat & Power Deployment » Market Analyses Market Analyses Need information on the market potential for combined heat and power (CHP) in the U.S.? These assessments and analyses cover a wide range of markets including commercial and institutional buildings and facilities, district energy, and industrial sites. The market potential for CHP at federal sites and in selected states/regions is also examined. Commercial CHP and Bioenergy Systems for Landfills and Wastewater Treatment

  7. miR-182 targets CHL1 and controls tumor growth and invasion in papillary thyroid carcinoma

    SciTech Connect (OSTI)

    Zhu, Hongling; Fang, Jin; Zhang, Jichen; Zhao, Zefei; Liu, Lianyong; Wang, Jingnan; Xi, Qian; Gu, Mingjun

    2014-07-18

    Highlights: miR-182 and CHL1 expression patterns are negatively correlated. CHL1 is a direct target of miR-182 in PTC cells. miR-182 suppression inhibits PTC cell growth and invasion. CHL1 is involved in miR-182-mediated cell behavior. - Abstract: In this study, we investigated the role and underlying mechanism of action of miR-182 in papillary thyroid carcinoma (PTC). Bioinformatics analysis revealed close homolog of LI (CHL1) as a potential target of miR-182. Upregulation of miR-182 was significantly correlated with CHL1 downregulation in human PTC tissues and cell lines. miR-182 suppressed the expression of CHL1 mRNA through direct targeting of the 3?-untranslated region (3?-UTR). Downregulation of miR-182 suppressed growth and invasion of PTC cells. Silencing of CHL1 counteracted the effects of miR-182 suppression, while its overexpression mimicked these effects. Our data collectively indicate that miR-182 in PTC promotes cell proliferation and invasion through direct suppression of CHL1, supporting the potential utility of miR-182 inhibition as a novel therapeutic strategy against PTC.

  8. Non-canonical microRNAs miR-320 and miR-702 promote proliferation in Dgcr8-deficient embryonic stem cells

    SciTech Connect (OSTI)

    Kim, Byeong-Moo; Choi, Michael Y.

    2012-09-21

    Highlights: Black-Right-Pointing-Pointer Embryonic stem cells (ESCs) lacking non-canonical miRNAs proliferate slower. Black-Right-Pointing-Pointer miR-320 and miR-702 are two non-canonical miRNAs expressed in ESCs. Black-Right-Pointing-Pointer miR-320 and miR-702 promote proliferation of Dgcr8-deficient ESCs. Black-Right-Pointing-Pointer miR-320 targets p57 and helps to release Dgcr8-deficient ESCs from G1 arrest. Black-Right-Pointing-Pointer miR-702 targets p21 and helps to release Dgcr8-deficient ESCs from G1 arrest. -- Abstract: MicroRNAs are known to contribute significantly to stem cell phenotype by post-transcriptionally regulating gene expression. Most of our knowledge of microRNAs comes from the study of canonical microRNAs that require two sequential cleavages by the Drosha/Dgcr8 heterodimer and Dicer to generate mature products. In contrast, non-canonical microRNAs bypass the cleavage by the Drosha/Dgcr8 heterodimer within the nucleus but still require cytoplasmic cleavage by Dicer. The function of non-canonical microRNAs in embryonic stem cells (ESCs) remains obscure. It has been hypothesized that non-canonical microRNAs have important roles in ESCs based upon the phenotypes of ESC lines that lack these specific classes of microRNAs; Dicer-deficient ESCs lacking both canonical and non-canonical microRNAs have much more severe proliferation defect than Dgcr8-deficient ESCs lacking only canonical microRNAs. Using these cell lines, we identified two non-canonical microRNAs, miR-320 and miR-702, that promote proliferation of Dgcr8-deficient ESCs by releasing them from G1 arrest. This is accomplished by targeting the 3 Prime -untranslated regions of the cell cycle inhibitors p57 and p21 and thereby inhibiting their expression. This is the first report of the crucial role of non-canonical microRNAs in ESCs.

  9. NuMI proton kicker extraction magnet termination resistor system

    SciTech Connect (OSTI)

    Reeves, S.R.; Jensen, C.C.; /Fermilab

    2005-05-01

    The temperature stability of the kicker magnet termination resistor assembly directly affects the field flatness and amplitude stability. Comprehensive thermal enhancements were made to the existing Main Injector resistor assembly design to satisfy NuMI performance specifications. Additionally, a fluid-processing system utilizing Fluorinert{reg_sign} FC-77 high-voltage dielectric was built to precisely control the setpoint temperature of the resistor assembly from 70 to 120F, required to maintain constant resistance during changing operational modes. The Fluorinert{reg_sign} must be continually processed to remove hazardous breakdown products caused by radiation exposure to prevent chemical attack of system components. Design details of the termination resistor assembly and Fluorinert{reg_sign} processing system are described. Early performance results will be presented.

  10. Petroleum marketing monthly

    SciTech Connect (OSTI)

    1996-07-01

    Petroleum Marketing Monthly (PPM) provides information and statistical data on a variety of crude oils and refined petroleum products. The publication presents statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the f.o. b. and landed cost of imported crude oil, and the refiners` acquisition cost of crude oil. Refined petroleum product sales data include motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane. The Petroleum Marketing Division, Office of Oil and Gas, Energy Information Administration ensures the accuracy, quality, and confidentiality of the published data in the Petroleum Marketing Monthly.

  11. Petroleum marketing monthly

    SciTech Connect (OSTI)

    1996-02-01

    The Petroleum Marketing Monthly (PMM) provides information and statistical data on a variety of crude oils and refined petroleum products. The publication presents statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the f.o.b. and landed cost of imported crude oil, and the refiners acquisition cost of crude oil. Refined petroleum product sales data include motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane. The Petroleum Marketing Division, Office of Oil and Gas, Energy Information Administration ensures the accuracy, quality, and confidentiality of the published data in the Petroleum Marketing Monthly.

  12. Petroleum marketing monthly

    SciTech Connect (OSTI)

    1995-08-01

    The Petroleum Marketing Monthly (PMM) provides information and statistical data on a variety of crude oils and refined petroleum products. The publication presents statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the f.o.b. and landed cost of imported crude oil, and the refiners` acquisition cost of crude oil. Refined petroleum product sales data include motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane. The Petroleum Marketing Division, Office of Oil and Gas, Energy Information Administration ensures the accuracy, quality, and confidentiality of the published data in the Petroleum Marketing Monthly.

  13. Energy Sector Market Analysis

    SciTech Connect (OSTI)

    Arent, D.; Benioff, R.; Mosey, G.; Bird, L.; Brown, J.; Brown, E.; Vimmerstedt, L.; Aabakken, J.; Parks, K.; Lapsa, M.; Davis, S.; Olszewski, M.; Cox, D.; McElhaney, K.; Hadley, S.; Hostick, D.; Nicholls, A.; McDonald, S.; Holloman, B.

    2006-10-01

    This paper presents the results of energy market analysis sponsored by the Department of Energy's (DOE) Weatherization and International Program (WIP) within the Office of Energy Efficiency and Renewable Energy (EERE). The analysis was conducted by a team of DOE laboratory experts from the National Renewable Energy Laboratory (NREL), Oak Ridge National Laboratory (ORNL), and Pacific Northwest National Laboratory (PNNL), with additional input from Lawrence Berkeley National Laboratory (LBNL). The analysis was structured to identify those markets and niches where government can create the biggest impact by informing management decisions in the private and public sectors. The analysis identifies those markets and niches where opportunities exist for increasing energy efficiency and renewable energy use.

  14. Distributed generation hits market

    SciTech Connect (OSTI)

    1997-10-01

    The pace at which vendors are developing and marketing gas turbines and reciprocating engines for small-scale applications may signal the widespread growth of distributed generation. Loosely defined to refer to applications in which power generation equipment is located close to end users who have near-term power capacity needs, distributed generation encompasses a broad range of technologies and load requirements. Disagreement is inevitable, but many industry observers associate distributed generation with applications anywhere from 25 kW to 25 MW. Ten years ago, distributed generation users only represented about 2% of the world market. Today, that figure has increased to about 4 or 5%, and probably could settle in the 20% range within a 3-to-5-year period, according to Michael Jones, San Diego, Calif.-based Solar Turbines Inc. power generation marketing manager. The US Energy Information Administration predicts about 175 GW of generation capacity will be added domestically by 2010. If 20% comes from smaller plants, distributed generation could account for about 35 GW. Even with more competition, it`s highly unlikely distributed generation will totally replace current market structures and central stations. Distributed generation may be best suited for making market inroads when and where central systems need upgrading, and should prove its worth when the system can`t handle peak demands. Typical applications include small reciprocating engine generators at remote customer sites or larger gas turbines to boost the grid. Additional market opportunities include standby capacity, peak shaving, power quality, cogeneration and capacity rental for immediate demand requirements. Integration of distributed generation systems--using gas-fueled engines, gas-fired combustion engines and fuel cells--can upgrade power quality for customers and reduce operating costs for electric utilities.

  15. Petroleum marketing monthly

    SciTech Connect (OSTI)

    1995-11-01

    The Petroleum Marketing Monthly (PMM) provides information and statistical data on a variety of crude oils and refined petroleum products. The publication presents statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the f.o.b. and landed cost of imported crude oil, and the refiners` acquisition cost of crude oil. Refined petroleum product sales data include motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane. The Petroleum Marketing Division, Office of Oil and Gas, Energy Information Administration ensures the accuracy, quality, and confidentiality of the published data.

  16. Christmas Market Cruise

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Reserve your cabin now for the HERO Christmas Market Cruise 2017 Pricing starts at $2195 per person and includes airfare from Seattle! HERO is traveling on the 2017 Christmas Market Cruise down the Danube November 24-December 2, 2017 for 8 days and 7 nights. The price includes airfare from Seattle (you can add on flight from Pasco and trip in- surance if you choose), trans- fers between the airport and the ship both ways plus all meals onboard, including wine, beer and soft drinks with dinner,

  17. Downregulation of miRNA-30c and miR-203a is associated with hepatitis C virus core protein-induced epithelial–mesenchymal transition in normal hepatocytes and hepatocellular carcinoma cells

    SciTech Connect (OSTI)

    Liu, Dongjing; Wu, Jilin; Liu, Meizhou; Yin, Hui; He, Jiantai; Zhang, Bo

    2015-09-04

    Hepatitis C virus (HCV) Core protein has been demonstrated to induce epithelial–mesenchymal transition (EMT) and is associated with cancer progression of hepatocellular carcinoma (HCC). However, how the Core protein regulates EMT is still unclear. In this study, HCV Core protein was overexpressed by an adenovirus. The protein levels of EMT markers were measured by Western blot. The xenograft animal model was established by inoculation of HepG2 cells. Results showed that ectopic expression of HCV core protein induced EMT in L02 hepatocytes and HepG2 tumor cells by upregulating vimentin, Sanl1, and Snal2 expression and downregulating E-cadherin expression. Moreover, Core protein downregulated miR-30c and miR-203a levels in L02 and HepG2 cells, but artificial expression of miR-30c and miR-203a reversed Core protein-induced EMT. Further analysis showed that ectopic expression of HCV core protein stimulated cell proliferation, inhibited apoptosis, and increased cell migration, whereas artificial expression of miR-30c and miR-203a significantly reversed the role of Core protein in these cell functions in L02 and HepG2 cells. In the HepG2 xenograft tumor models, artificial expression of miR-30c and miR-203a inhibited EMT and tumor growth. Moreover, L02 cells overexpressing Core protein can form tumors in nude mice. In HCC patients, HCV infection significantly shortened patients' survival time, and loss of miR-30c and miR-203 expression correlated with poor survival. In conclusion, HCV core protein downregulates miR-30c and miR-203a expression, which results in activation of EMT in normal hepatocytes and HCC tumor cells. The Core protein-activated-EMT is involved in the carcinogenesis and progression of HCC. Loss of miR-30c and miR-203a expression is a marker for the poor prognosis of HCC. - Highlights: • HCV core protein downregulates miR-30c and miR-203a expression. • Downregulation of miR-30c and miR-203a activates EMT. • Activated-EMT is involved in the

  18. miR-128 and its target genes in tumorigenesis and metastasis

    SciTech Connect (OSTI)

    Li, Molin, E-mail: molin_li@hotmail.com [Dalian Medical University, Dalian 116044 (China); Fu, Weiming [Center for Food Safety and Environmental Technology, Guangzhou Institute of Advanced Technology, Chinese Academy of Sciences, Guangzhou 511458 (China); Wo, Lulu; Shu, Xiaohong [Dalian Medical University, Dalian 116044 (China); Liu, Fang [The second affiliated hospital of Dalian Medical University, Dalian 116023 (China); Li, Chuangang, E-mail: li_chuangang@sina.com [The second affiliated hospital of Dalian Medical University, Dalian 116023 (China)

    2013-12-10

    MicroRNAs (miRNAs) are a class of endogenous, non-coding, 1824 nucleotide length single-strand RNAs that could modulate gene expression at post-transcriptional level. Previous studies have shown that miR-128 enriched in the brain plays an important role in the development of nervous system and the maintenance of normal physical functions. Aberrant expression of miR-128 has been detected in many types of human tumors and its validated target genes are involved in cancer-related biological processes such as cell proliferation, differentiation and apoptosis. In this review, we will summarize the roles of miR-128 and its target genes in tumorigenesis and metastasis. - Highlights: Aberrant expression of miR-128 can be observed in many kinds of malignant tumors. The molecular mechanisms regulating miR-128 expression are elucidated. Roles of miR-128 and its target genes in tumorigenesis and metastasis are summarized.

  19. miR-125b inhibits osteoblastic differentiation by down-regulation of cell proliferation

    SciTech Connect (OSTI)

    Mizuno, Yosuke; Yagi, Ken; Tokuzawa, Yoshimi; Kanesaki-Yatsuka, Yukiko; Suda, Tatsuo; Katagiri, Takenobu; Fukuda, Toru; Maruyama, Masayoshi; Okuda, Akihiko; Amemiya, Tomoyuki; Kondoh, Yasumitsu; Tashiro, Hideo; Okazaki, Yasushi

    2008-04-04

    Although various microRNAs regulate cell differentiation and proliferation, no miRNA has been reported so far to play an important role in the regulation of osteoblast differentiation. Here we describe the role of miR-125b in osteoblastic differentiation in mouse mesenchymal stem cells, ST2, by regulating cell proliferation. The expression of miR-125b was time-dependently increased in ST2 cells, and the increase in miR-125b expression was attenuated in osteoblastic-differentiated ST2 cells induced by BMP-4. The transfection of exogenous miR-125b inhibited proliferation of ST2 cells and caused inhibition of osteoblastic differentiation. In contrast, when the endogenous miR-125b was blocked by transfection of its antisense RNA molecule, alkaline phosphatase activity after BMP-4 treatment was elevated. These results strongly suggest that miR-125b is involved in osteoblastic differentiation through the regulation of cell proliferation.

  20. Wind Energy Markets, 2. edition

    SciTech Connect (OSTI)

    2007-11-15

    The report provides an overview of the global market for wind energy, including a concise look at wind energy development in key markets including installations, government incentives, and market trends. Topics covered include: an overview of wind energy including the history of wind energy production and the current market for wind energy; key business drivers of the wind energy market; barriers to the growth of wind energy; key wind energy trends and recent developments; the economics of wind energy, including cost, revenue, and government subsidy components; regional and national analyses of major wind energy markets; and, profiles of key wind turbine manufacturers.

  1. Solar Market Pathways Website

    Broader source: Energy.gov [DOE]

    The Solar Market Pathways website distributes key insights from 15 SunShot Initiative projects that are advancing solar deployment across the United States. These projects take a variety of approaches to develop actionable strategic plans to expand solar electricity use for residential, community, and commercial properties.

  2. Solar Market Pathways

    Broader source: Energy.gov [DOE]

    The Solar Market Pathways website distributes key insights from 15 SunShot Initiative projects that are advancing solar deployment across the United States. These projects take a variety of approaches to develop actionable strategic plans to expand solar electricity use for residential, community, and commercial properties.

  3. Marketing Strategy and Implementation

    SciTech Connect (OSTI)

    2010-05-31

    This report documents the marketing campaign that has been designed for middle and high school students in New Mexico to increase interest in participation in national security careers at the National Nuclear Security Administration. This marketing campaign builds on the research that was previously conducted, as well as the focus groups that were conducted. This work is a part of the National Nuclear Security Preparedness Project (NSPP) being performed under a Department of Energy (DOE) / National Nuclear Security Administration (NNSA) grant. Outcome analysis was performed to determine appropriate marketing strategies. The analysis was based upon focus groups with middle school and high school students, student interactions, and surveys completed by students to understand and gauge student interest in Science, Technology, Engineering, and Math (STEM) subjects, interest in careers at NNSA, future job considerations, and student desire to pursue post-secondary education. Further, through the focus groups, students were asked to attend a presentation on NNSA job opportunities and employee requirements. The feedback received from the students was utilized to develop the focus and components of the marketing campaign.

  4. Market values summary/April market review/current market data

    SciTech Connect (OSTI)

    1995-05-01

    This article is the April 1995 uranium market summary. Overall market activity during this period was low, with five deals in the concentrates market, two deals in the long-term natural uranium market, and three deals in the spot enrichment market. There were no spot trades in the UF6 or conversion market. The restricted and unrestricted exchange values were $11.60 and $7.35 respectively. The restricted and unrestricted UF6 values were $36.00 and $25.50, and the restricted and unrestricted transaction values were $10.30 and $7.25. Active uranium supply rose, and active demand fell.

  5. Sandia Energy - Conventional Water Power: Market Acceleration

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Market Acceleration Home Stationary Power Energy Conversion Efficiency Water Power Conventional Water Power: Market Acceleration Conventional Water Power: Market AccelerationTara...

  6. Solar Market Pathways | Department of Energy

    Energy Savers [EERE]

    Solar Market Pathways Solar Market Pathways The Solar Market Pathways program supports 15 SunShot projects that are advancing solar deployment across the United States. These...

  7. EnviroMarket | Open Energy Information

    Open Energy Info (EERE)

    EnviroMarket Jump to: navigation, search Name: EnviroMarket Place: England, United Kingdom Sector: Carbon Product: EnviroMarket provides technical support and advice to corporate,...

  8. Demonstration and Market Transformation | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    and Market Transformation Demonstration and Market Transformation POET-DSM's Project ... Aerial view of the Abengoa biorefinery in Hugoton, Kansas The Demonstration and Market ...

  9. Hydropower Market Report | Department of Energy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Hydropower Market Report Hydropower Market Report Hydropower Market Report Top 10 Things You Didn't Know about Hydropower An error occurred. Try watching this video on...

  10. 2015 Uranium Marketing Annual Report

    U.S. Energy Information Administration (EIA) Indexed Site

    2015 Uranium Marketing Annual Report 2015 Uranium Marketing Annual Report Release Date: May 24, 2016 Next Release Date: May 2017 thousand pounds U 3 O 8 equivalent Year Maximum ...

  11. 2015 Uranium Marketing Annual Report

    Gasoline and Diesel Fuel Update (EIA)

    Uranium Marketing Annual Report 2015 Uranium Marketing Annual Report Release Date: May 24, 2016 Next Release Date: May 2017 2014 2015 2014 2015 2014 2015 Weighted-average price ...

  12. Momentum Savings Market Research Update

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    collected before with a larger market share than we had last year. Expect to see a market intelligence report in late April and a draft savings model available for comment on our...

  13. Overexpression of miR-206 suppresses glycolysis, proliferation and migration in breast cancer cells via PFKFB3 targeting

    SciTech Connect (OSTI)

    Ge, Xin; Lyu, Pengwei; Cao, Zhang; Li, Jingruo; Guo, Guangcheng; Xia, Wanjun; Gu, Yuanting

    2015-08-07

    miRNAs, sorting as non-coding RNAs, are differentially expressed in breast tumor and act as tumor promoters or suppressors. miR-206 could suppress the progression of breast cancer, the mechanism of which remains unclear. The study here was aimed to investigate the effect of miR-206 on human breast cancers. We found that miR-206 was down-regulated while one of its predicted targets, 6-Phosphofructo-2-kinase (PFKFB3) was up-regulated in human breast carcinomas. 17β-estradiol dose-dependently decreased miR-206 expression as well as enhanced PFKFB3 mRNA and protein expression in estrogen receptor α (ERα) positive breast cancer cells. Furthermore, we identified that miR-206 directly interacted with 3′-untranslated region (UTR) of PFKFB3 mRNA. miR-206 modulated PFKFB3 expression in MCF-7, T47D and SUM159 cells, which was influenced by 17β-estradiol depending on ERα expression. In addition, miR-206 overexpression impeded fructose-2,6-bisphosphate (F2,6BP) production, diminished lactate generation and reduced cell proliferation and migration in breast cancer cells. In conclusion, our study demonstrated that miR-206 regulated PFKFB3 expression in breast cancer cells, thereby stunting glycolysis, cell proliferation and migration. - Highlights: • miR-206 was down-regulated and PFKFB3 was up-regulated in human breast carcinomas. • 17β-estradiol regulated miR-206 and PFKFB3 expression in ERα+ cancer cells. • miR-206directly interacted with 3′-UTR of PFKFB3 mRNA. • miR-206 fructose-2,6-bisphosphate (F2,6BP) impeded production and lactate generation. • miR-206 reduced cell proliferation and migration in breast cancer cells.

  14. NREL: Energy Analysis - Market Analysis

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Market Analysis The laboratory's market analysis helps increase the use of renewable energy (RE) and energy efficiency (EE) technologies in the marketplace by providing strategic information to stakeholders interested in rapidly changing electricity markets. Our high-quality and objective crosscutting assessments and analysis support informed decision making. Primary focuses include: Energy Technology/Program Cost, Performance, and Market Data The Office of Energy Efficiency and Renewable Energy

  15. Technology to Market Fact Sheet

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    to Market The SunShot Initiative's Technology to Market subprogram builds on SunShot's record of moving groundbreaking and early-stage technologies and business models through developmental phases to commercialization. Technology to Market targets two known funding gaps: those that occur at the prototype commercialization stage and those at the commercial scale-up stage. There are four main funding programs under Technology to Market, each of which addresses innovations in technology

  16. Market Studies | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Information Resources » Publications » Market Studies Market Studies This page contains links to lighting market characterization studies published by the U.S. Department of Energy, plus information on current studies under way. These studies are intended to present objective market analysis based on the most recent, referenceable data available at the time of preparation of the reports. As new information becomes available, DOE will make efforts to update these studies as necessary. While

  17. AMENDMENT OF SOLICITATION/MODIFICATlON OF CONTRACT MI54 I See...

    National Nuclear Security Administration (NNSA)

    MI54 I See Block 16C I REQ. NO. Babcock & Wilcox Technical Services Pantex, LLC PO Box 30020 Amarillo, TX 79120 2. AMENDMENTIMODIFICATION NO. 1 3. EFFECTIVE DATE 1 4. ...

  18. File:USDA-CE-Production-GIFmaps-MI.pdf | Open Energy Information

    Open Energy Info (EERE)

    MI.pdf Jump to: navigation, search File File history File usage Michigan Ethanol Plant Locations Size of this preview: 463 599 pixels. Other resolution: 464 600 pixels. Full...

  19. Petroleum marketing annual, 1991

    SciTech Connect (OSTI)

    Not Available

    1992-08-01

    The Petroleum Marketing Annual contains statistical data on a variety of crude oils and refined petroleum products. The publication provides statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the free-on-board and landed cost of imported crude oil, and the refiners` acquisition cost of crude oil. Sales data for motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane are presented. For this publication, all estimates have been recalculated since their earlier publication in the Petroleum Marketing Monthly (PMM). These calculations made use of additional data and corrections that were received after the PMM publication dates.

  20. Petroleum marketing annual 1993

    SciTech Connect (OSTI)

    Not Available

    1995-01-01

    The Petroleum Marketing Annual (PMA) contains statistical data on a variety of crude oils and refined petroleum products. The publication provides statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the free-on-board (f.o.b.) and landed cost of imported crude oil, and the refiners acquisition cost of crude oil. Sales data for motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane are presented. For this publication, all estimates have been recalculated since their earlier publication in the Petroleum Marketing Monthly (PMM). These calculations made use of additional data and corrections that were received after the PMM publication dates.

  1. Distributed Wind Market Applications

    SciTech Connect (OSTI)

    Forsyth, T.; Baring-Gould, I.

    2007-11-01

    Distributed wind energy systems provide clean, renewable power for on-site use and help relieve pressure on the power grid while providing jobs and contributing to energy security for homes, farms, schools, factories, private and public facilities, distribution utilities, and remote locations. America pioneered small wind technology in the 1920s, and it is the only renewable energy industry segment that the United States still dominates in technology, manufacturing, and world market share. The series of analyses covered by this report were conducted to assess some of the most likely ways that advanced wind turbines could be utilized apart from large, central station power systems. Each chapter represents a final report on specific market segments written by leading experts in this field. As such, this document does not speak with one voice but rather a compendium of different perspectives, which are documented from a variety of people in the U.S. distributed wind field.

  2. Marketing Strategy Research

    SciTech Connect (OSTI)

    2010-03-31

    This report documents the research that has been undertaken as background for preparation of a marketing campaign for middle and high school students to increase interest in national security careers at the National Nuclear Security Administration. This work is a part of the National Security Preparedness Project (NSPP), being performed under a Department of Energy (DOE)/National Nuclear Security Administration (NNSA) grant. Previous research on the development of a properly trained and skilled national security workforce has identified a lack of interest by k-12 students in the STEM (Science, Technology, Engineering, and Mathematics) fields. Further, participation in these careers by women and minority populations is limited and is not increasing. Added to this are low educational achievement levels in New Mexico, where the marketing campaign will be deployed.

  3. View on world market

    SciTech Connect (OSTI)

    Poulsen, J.

    1996-12-31

    Opinions on the world market for wind power are presented in this paper. Reasons contributing to a potential growth in wind power are cited. Increased demand is expected to arise due to increased energy needs and environmental concerns. Barriers, primarily political, to the development of wind energy are assessed. Development is predicted to occur first in countries with a demand for new capacity and political decisions to protect the environment.

  4. Market Acceleration & Deployment

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Market Acceleration & Deployment - Sandia Energy Energy Search Icon Sandia Home Locations Contact Us Employee Locator Energy & Climate Secure & Sustainable Energy Future Stationary Power Energy Conversion Efficiency Solar Energy Wind Energy Water Power Supercritical CO2 Geothermal Natural Gas Safety, Security & Resilience of the Energy Infrastructure Energy Storage Nuclear Power & Engineering Grid Modernization Battery Testing Nuclear Energy Defense Waste Management Programs

  5. Marketing Strategy and Implementation

    SciTech Connect (OSTI)

    2010-09-30

    This report documents the preparation of materials for the marketing campaign that has been designed for middle and high school students in New Mexico to increase interest in participation in national security careers at the National Nuclear Security Administration. The materials and the marketing campaign build on the research that was previously completed, as well as the focus groups that were conducted. This work is a part of the National Nuclear Security Preparedness Project (NSPP). Previous research included outcome analysis to determine appropriate marketing strategies. The analysis was based upon focus groups with middle school and high school students, student interactions, and surveys completed by students to understand and gauge student interest in Science, Technology, Engineering, and Math (STEM) subjects, interest in careers at NNSA, future job considerations, and student desire to pursue post-secondary education. Further, through the focus groups, students were asked to attend a presentation on NNSA job opportunities and employee requirements. The feedback received from the students was utilized to develop the focus and components of a marketing campaign divided into DISCO (Discovering Intelligence and Security Career Opportunities) for the middle school age group and DISCO…..Your Way! for high school age groups. Both campaigns have an intertwined message that focuses on the education of students in the various national security career opportunities at NNSA using the STEM concepts and the notion that almost any career they can think of has a fit within NNSA. Further, a special emphasis has been placed on the importance of obtaining a national security clearance when working at NNSA and the steps that will need to be taken during middle school, high school, and college to be allowed this opportunity.

  6. 2014 Hydropower Market Report

    SciTech Connect (OSTI)

    Uria-Martinez, Rocio; O'Connor, Patrick W.; Johnson, Megan M.

    2015-04-30

    The U.S. hydropower fleet has been providing clean, reliable power for more than a hundred years. However, no systematic documentation exists of the U.S. fleet and the trends influencing it in recent years. This first-ever Hydropower Market Report seeks to fill this gap and provide industry and policy makers with a quantitative baseline on the distribution, capabilities, and status of hydropower in the United States.

  7. Climate Action Champions: Sault Ste. Marie Tribe of Chippewa Indians, MI |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Sault Ste. Marie Tribe of Chippewa Indians, MI Climate Action Champions: Sault Ste. Marie Tribe of Chippewa Indians, MI The Sault Ste. Marie Tribe of Chippewa Indians is a 44,000-strong federally recognized Indian tribe that is an economic, social and cultural force in its community across the eastern Upper Peninsula counties of Chippewa, Luce, Mackinac, Schoolcraft, Alger, Delta and Marquette, with housing and tribal centers, casinos, and other enterprises that employ

  8. Taking technology to market

    SciTech Connect (OSTI)

    Ford, D.; Ryan, C.

    1981-03-01

    For many years, the concept of the product life cycle has helped managers maximize their return on product sales. But according to the authors of this article, using a technology solely in product sales is no longer enough. Today, companies face high R and D costs, competitive pressures from low-cost producers, capacity limitations, antitrust laws, financial difficulties, and foreign trade barriers. This means that they must improve the rate of return on their technology investments by marketing their technology as completely as possible during all phases of its life cycle. The technology life cycle - derived from the product life cycle - pinpoints the changing decisions companies face in selling their know-how. The authors also discuss both the competitive dangers of transferring technology to low-cost foreign producers and the growing role of intermediaries in technology sales. They stress the importance of having a highly specialized staff to plan a company's technology marketing, a responsibility that should be assigned neither to the part-time attention of top management nor simply to marketers or strategic planners.

  9. Fuel cell market applications

    SciTech Connect (OSTI)

    Williams, M.C.

    1995-12-31

    This is a review of the US (and international) fuel cell development for the stationary power generation market. Besides DOE, GRI, and EPRI sponsorship, the US fuel cell program has over 40% cost-sharing from the private sector. Support is provided by user groups with over 75 utility and other end-user members. Objectives are to develop and demonstrate cost-effective fuel cell power generation which can initially be commercialized into various market applications using natural gas fuel by the year 2000. Types of fuel cells being developed include PAFC (phosphoric acid), MCFC (molten carbonate), and SOFC (solid oxide); status of each is reported. Potential international applications are reviewed also. Fuel cells are viewed as a force in dispersed power generation, distributed power, cogeneration, and deregulated industry. Specific fuel cell attributes are discussed: Fuel cells promise to be one of the most reliable power sources; they are now being used in critical uninterruptible power systems. They need hydrogen which can be generated internally from natural gas, coal gas, methanol landfill gas, or other fuels containing hydrocarbons. Finally, fuel cell development and market applications in Japan are reviewed briefly.

  10. Electricity Market Complex Adaptive System

    Energy Science and Technology Software Center (OSTI)

    2004-10-14

    EMCAS is a model developed for the simulation and analysis of electricity markets. As power markets are relatively new and still continue to evolve, there is a growing need for advanced modeling approaches that simulate the behavior of electricity markets over time and how market participants may act and react to the changing economic, financial, and regulatory environments in which they operate. A new and rather promising approach applied in the EMCAS software is tomore » model the electricity market as a complex adaptive system using an agent-based modeling and simulation scheme. With its unique combination of various novel approaches, the Agent Based Modeling System (ABMS) provides the ability to capture and investigate the complex interactions between the physical infrastructures (generation, transmission, and distribution) and the economic behavior of market participants that are a trademark of the newly emerging markets.« less

  11. Energy Information Administration/Petroleum Marketing Annual

    U.S. Energy Information Administration (EIA) Indexed Site

    . . . . . . . . . . . . . . June 1994 400 Energy Information AdministrationPetroleum Marketing Annual 1999 Changes to the 1994 Petroleum Marketing Monthly. . . . . . . . . . . . ....

  12. Hydrogen Infrastructure Market Readiness Workshop: Preliminary...

    Broader source: Energy.gov (indexed) [DOE]

    Preliminary results from the Hydrogen Infrastructure Market Readiness Workshop held ... More Documents & Publications Hydrogen Infrastructure Market Readiness: Opportunities and ...

  13. Leveraging Seasonal Opportunities for Marketing Energy Efficiency...

    Energy Savers [EERE]

    Seasonal Opportunities for Marketing Energy Efficiency Leveraging Seasonal Opportunities for Marketing Energy Efficiency Better Buildings Residential Network Peer Exchange Call ...

  14. Market Transformation Fact Sheet | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Market Transformation Fact Sheet Market Transformation Fact Sheet This fact sheet describes the Fuel Cell Technologies Office's Market Transformation strategies and activities, which are aimed at accelerating early market adoption and advancing pre-competitive technologies. Market Transformation (1.49 MB) More Documents & Publications Early Markets: Fuel Cells for Material Handling Equipment Identification and Characterization of Near-Term Direct Hydrogen PEM Fuel Cell Markets Early Markets:

  15. miR-196a targets netrin 4 and regulates cell proliferation and migration of cervical cancer cells

    SciTech Connect (OSTI)

    Zhang, Jie; Zheng, Fangxia; Yu, Gang; Yin, Yanhua; Lu, Qingyang

    2013-11-01

    Highlights: miR-196a was overexpressed in cervical cancer tissue compared to normal tissue. miR-196a expression elevated proliferation and migration of cervical cancer cells. miR-196a inhibited NTN4 expression by binding 3?-UTR region of NTN4 mRNA. NTN4 inversely correlated with miR-196a expression in cervical tissue and cell line. NTN4 expression was low in cervical cancer tissue compared to normal tissue. -- Abstract: Recent research has uncovered tumor-suppressive and oncogenic potential of miR-196a in various tumors. However, the expression and mechanism of its function in cervical cancer remains unclear. In this study, we assess relative expression of miR-196a in cervical premalignant lesions, cervical cancer tissues, and four cancer cell lines using quantitative real-time PCR. CaSki and HeLa cells were treated with miR-196a inhibitors, mimics, or pCDNA/miR-196a to investigate the role of miR-196a in cancer cell proliferation and migration. We demonstrated that miR-196a was overexpressed in cervical intraepithelial neoplasia 23 and cervical cancer tissue. Moreover, its expression contributes to the proliferation and migration of cervical cancer cells, whereas inhibiting its expression led to a reduction in proliferation and migration. Five candidate targets of miR-196a chosen by computational prediction and Cervical Cancer Gene Database search were measured for their mRNA in both miR-196a-overexpressing and -depleted cancer cells. Only netrin 4 (NTN4) expression displayed an inverse association with miR-196a. Fluorescent reporter assays revealed that miR-196a inhibited NTN4 expression by targeting one binding site in the 3?-untranslated region (3?-UTR) of NTN4 mRNA. Furthermore, qPCR and Western blot assays verified NTN4 expression was downregulated in cervical cancer tissues compared to normal controls, and in vivo mRNA level of NTN4 inversely correlated with miR-196a expression. In summary, our findings provide new insights about the functional role of

  16. Power marketing and renewable energy

    SciTech Connect (OSTI)

    Fang, J.M.

    1997-09-01

    Power marketing refers to wholesale and retail transactions of electric power made by companies other than public power entities and the regulated utilities that own the generation and distribution lines. The growth in power marketing has been a major development in the electric power industry during the last few years, and power marketers are expected to realize even more market opportunities as electric industry deregulation proceeds from wholesale competition to retail competition. This Topical Issues Brief examines the nature of the power marketing business and its relationship with renewable power. The information presented is based on interviews conducted with nine power marketing companies, which accounted for almost 54% of total power sales by power marketers in 1995. These interviews provided information on various viewpoints of power marketers, their experience with renewables, and their respective outlooks for including renewables in their resource portfolios. Some basic differences exist between wholesale and retail competition that should be recognized when discussing power marketing and renewable power. At the wholesale level, the majority of power marketers stress the commodity nature of electricity. The primary criteria for developing resource portfolios are the same as those of their wholesale customers: the cost and reliability of power supplies. At the retail level, electricity may be viewed as a product that includes value-added characteristics or services determined by customer preferences.

  17. Exploring Your Energy Markets

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Exploring Your Energy Markets February 24, 2016 11:00 am - 12:30 PM MST Tribal Energy Development Operation and Management Best Practices 2 Todays Presenters * Randy Manion manion@wapa.gov * Doug MacCourt Douglas.Maccourt@hq.doe.gov * Philipp Beiter philipp.beiter@nrel.gov * Al Austin austin@wapa.gov * Todd Hegwer toddhegwer@gmail.com * Wenona Benally Baldenegro wbenally@navajo- nsn.gov * Robert Kennedy Robert.Kennedy@tetratech.com 3 Link to the Webinar Slides and Audio Everyone will receive a

  18. Energy Markets Outlook

    Gasoline and Diesel Fuel Update (EIA)

    Energy Markets Outlook For National Association for Business Economics March 7, 2016 | Washington, D.C. By Adam Sieminski, Administrator Forecast -3 -2 -1 0 1 2 3 4 5 6 82 84 86 88 90 92 94 96 98 100 2011-Q1 2012-Q1 2013-Q1 2014-Q1 2015-Q1 2016-Q1 2017-Q1 Implied stock change and balance (right axis) World production (left axis) World consumption (left axis) world supply and demand million barrels per day implied stock change million barrels per day Global oil inventories are forecast to

  19. Market Research Report - Global Open Source Software Market Size...

    Open Energy Info (EERE)

    we deeply analyzed the world's main region market conditions that including the product price, profit, capacity, production, capacity utilization, supply, demand and industry...

  20. miR-214 promotes the proliferation and invasion of osteosarcoma cells through direct suppression of LZTS1

    SciTech Connect (OSTI)

    Xu, Zhengyu; Wang, Tao

    2014-06-27

    Highlights: • miR-214 is upregulated in human OS tissues and inversely correlated with LZTS1 expression. • miR-214 directly targets LZTS1 by binding to its 3′-UTR. • miR-214 promotes OS cell proliferation, invasion and tumor growth. • Overexpression of LZTS1 reverses miR-214-induced proliferation and invasion of OS cells. - Abstract: Previous studies have shown that miR-214 functions either as an oncogene or a tumor suppressor in various human cancer types. The role of this microRNA in osteosarcoma (OS) is presently unclear. Here, we demonstrated that miR-214 is frequently upregulated in OS specimens, compared with noncancerous bone tissues. Bioinformatics analysis further revealed leucine zipper, putative tumor suppressor 1 (LZTS1) as a potential target of miR-214. Expression patterns of miR-214 were inversely correlated with those of LZTS1 mRNA and protein in OS tissues. Data from reporter assays showed that miR-214 directly binds to the 3′-untranslated region (3′-UTR) of LZTS1 mRNA and suppresses expression at both transcriptional and translational levels. In functional assays, miR-214 promoted OS cell proliferation, invasion and tumor growth in nude mice, which could be reversed by overexpression of LZTS1. Taken together, our data provide compelling evidence that miR-214 functions as an onco-miRNA in OS, and its oncogenic effects are mediated chiefly through downregulation of LZTS1.

  1. Market Transformation (Fact Sheet)

    SciTech Connect (OSTI)

    Not Available

    2011-10-01

    Through the SunShot Initiative, the U.S. Department of Energy (DOE) works with manufacturers, communities, states, utilities, and other partners to enable the solar market by reducing non-hardware balance-of-system (BOS) costs, developing a skilled workforce, and eliminating market barriers to widespread adoption of solar technologies. The DOE SunShot Initiative is a collaborative national initiative to make solar energy technologies cost-competitive with other forms of energy by reducing the cost of solar energy systems by about 75% by the end of the decade. Reducing the total installed cost for utility-scale solar electricity to roughly 6 cents per kilowatt hour without subsidies will result in rapid, large-scale adoption of solar electricity across the United States. Reaching this goal will re-establish American technological leadership, improve the nation's energy security, and strengthen U.S. economic competitiveness in the global clean energy race. SunShot will work to bring down the full cost of solar - including the costs of solar cells and installation by focusing on four main pillars: (1) Technologies for solar cells and arrays that convert sunlight to energy; (2) Electronics that optimize the performance of the installation; (3) Improvements in the efficiency of solar manufacturing processes; and (4) Installation, design, and permitting for solar energy systems.

  2. Facing the free market

    SciTech Connect (OSTI)

    Zimmer, M.J.; McManus, B.J.

    1995-02-01

    The move to deregulation is pushing power generators at all levels to deal with the contract reformation and stranded investment issues. Both FERC and state commissions recognize that the identification and recovery of the costs stranded by the changes in regulatory policies favoring the unbundling of services must be resolved in this new era. Whether the concept of stranded costs and their recovery is compatible with a competitive market for electricity still awaits final resolution. A new day has come in which the old rules and methods may have little value or offer only slight guidance. Ultimately, utilities and NUGs are the parties who must seek a creative and reasonable solution which is compatible with that elusive standard known as the public interest. They are the stakeholders confronting most of the financial risk caused by the realization of stranded investment or the threat of such a financial loss. What is needed now is a willingness to adopt a whole new philosophy to deal with economic risks that are natural in transitioning to a fully competitive market.

  3. Strengthening Building Retrofit Markets

    SciTech Connect (OSTI)

    Templeton, Mary; Jackson, Robert

    2014-04-15

    The Business Energy Financing (BEF) program offered commercial businesses in Michigan affordable financing options and other incentives designed to support energy efficiency improvements. We worked through partnerships with Michigan utilities, lenders, building contractors, trade associations, and other community organizations to offer competitive interest rates and flexible financing terms to support energy efficiency projects that otherwise would not have happened. The BEF program targeted the retail food market, including restaurants, grocery stores, convenience stores, and wholesale food vendors, with the goal of achieving energy efficiency retrofits for 2 percent of the target market. We offered low interest rates, flexible payments, easy applications and approval processes, and access to other incentives and rebates. Through these efforts, we sought to help customers strive for energy savings retrofits that would save 20 percent or more on their energy use. This program helped Michigan businesses reduce costs by financing energy efficient lighting, heating and cooling systems, insulation, refrigeration, equipment upgrades, and more. Businesses completed the upgrades with the help of our authorized contractors, and, through our lending partners, we provided affordable financing options.

  4. Market Transformation | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Market Transformation Market Transformation Significant research and development progress has paved the way for fuel cells to enter today's commercial marketplace for a variety of applications, including specialty vehicles and stationary and portable power. The growing number of commercial products, in combination with the federal and state financial incentives available now, are instrumental in supporting the role that fuel cells play in our nation's energy portfolio. Through its market

  5. miR-421 induces cell proliferation and apoptosis resistance in human nasopharyngeal carcinoma via downregulation of FOXO4

    SciTech Connect (OSTI)

    Chen, Liang; Department of Otolaryngology, Guangzhou General Hospital of PLA Guangzhou Command, Guangzhou 510010 ; Tang, Yanping; Wang, Jian; Yan, Zhongjie; Xu, Ruxiang

    2013-06-14

    Highlights: •miR-421 is upregulated in nasopharyngeal carcinoma. •miR-421 induces cell proliferation and apoptosis resistance. •FOXO4 is a direct and functional target of miR-421. -- Abstract: microRNAs have been demonstrated to play important roles in cancer development and progression. Hence, identifying functional microRNAs and better understanding of the underlying molecular mechanisms would provide new clues for the development of targeted cancer therapies. Herein, we reported that a microRNA, miR-421 played an oncogenic role in nasopharyngeal carcinoma. Upregulation of miR-421 induced, whereas inhibition of miR-421 repressed cell proliferation and apoptosis resistance. Furthermore, we found that upregulation of miR-421 inhibited forkhead box protein O4 (FOXO4) signaling pathway following downregulation of p21, p27, Bim and FASL expression by directly targeting FOXO4 3′UTR. Additionally, we demonstrated that FOXO4 expression is critical for miR-421-induced cell growth and apoptosis resistance. Taken together, our findings not only suggest that miR-421 promotes nasopharyngeal carcinoma cell proliferation and anti-apoptosis, but also uncover a novel regulatory mechanism for inactivation of FOXO4 in nasopharyngeal carcinoma.

  6. 2014 Uranium Marketing Annual Report

    U.S. Energy Information Administration (EIA) Indexed Site

    By law, EIA's data, analyses, and forecasts are independent ... on information reported on Form EIA-858, "Uranium Marketing ... nuclear power reactors by contract type and material type, ...

  7. Natural gas marketing and transportation

    SciTech Connect (OSTI)

    Not Available

    1991-01-01

    This book covers: Overview of the natural gas industry; Federal regulation of marketing and transportation; State regulation of transportation; Fundamentals of gas marketing contracts; Gas marketing options and strategies; End user agreements; Transportation on interstate pipelines; Administration of natural gas contracts; Structuring transactions with the nonconventional source fuels credit; Take-or-pay wars- a cautionary analysis for the future; Antitrust pitfalls in the natural gas industry; Producer imbalances; Natural gas futures for the complete novice; State non-utility regulation of production, transportation and marketing; Natural gas processing agreements and Disproportionate sales, gas balancing, and accounting to royalty owners.

  8. 2015 Uranium Marketing Annual Report

    Gasoline and Diesel Fuel Update (EIA)

    3 2015 Uranium Marketing Annual Report Release Date: May 24, 2016 Next Release Date: May 2017 Quantity with reported price Weighted-average price Quantity with reported price ...

  9. 2015 Uranium Market Annual Report

    U.S. Energy Information Administration (EIA) Indexed Site

    received in 2015","Weighted-average price","Number of purchase contracts for ... Administration, Form EIA-858 ""Uranium Marketing Annual Survey"" (2015)." "16 ...

  10. 2015 Uranium Marketing Annual Survey

    U.S. Energy Information Administration (EIA) Indexed Site

    5 2015 Uranium Marketing Annual Report Release Date: May 24, 2016 Next Release Date: May 2017 Quantity with reported price Weighted-average price Quantity with reported price ...

  11. 2015 Uranium Market Annual Report

    U.S. Energy Information Administration (EIA) Indexed Site

    U.S. Energy Information Administration 2015 Uranium Marketing Annual Report 2015 Uranium ... received in 2015 Weighted-average price Number of purchase contracts for ...

  12. 2008 Geothermal Technologies Market Report

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    JULY 2009 2008 GEOTHERMAL TECHNOLOGIES MARKET REPORT Energy Efficiency & Renewable Energy (This page intentionally left blank) Table of Contents Executive Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Major 2008 Highlights . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

  13. Momentum Savings Market Research Update

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    programs? Are you excited about improving programs from Momentum Savings market research? And what IS a current practice baseline? Early next year we will be tackling this...

  14. 2013 Distributed Wind Market Report

    SciTech Connect (OSTI)

    Orrell, A. C.

    2014-08-15

    This report describes the status of the U.S. distributed wind industry in 2013; its trends, performance, market drivers and future outlook.

  15. CBEI Transitioning Technology to Market

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... require support to engage. TECHNOLOGY TRANSFER Licensing terms may have a greater ... may not be as significant of a decision factor 8 Preliminary Results of Market Analysis ...

  16. Factors affecting robust retail energy markets

    SciTech Connect (OSTI)

    Michelman, T.S.

    1999-04-01

    This paper briefly defines an active retail market, details the factors that influence market activity and their relative importance, compares activity in various retail energy markets to date, and predicts future retail energy market activity. Three primary factors translate into high market activity: supplier margins, translated into potential savings for actively shopping customers; market size; and market barriers. The author surveys activity nationwide and predicts hot spots for the coming year.

  17. Roles of miRNAs in microcystin-LR-induced Sertoli cell toxicity

    SciTech Connect (OSTI)

    Zhou, Yuan; Wang, Hui; Wang, Cong; Qiu, Xuefeng; Benson, Mikael; Yin, Xiaoqin; Xiang, Zou; Li, Dongmei; and others

    2015-08-15

    Microcystin (MC)-LR, a cyclic heptapeptide, is a potent reproductive system toxin. To understand the molecular mechanisms of MC-induced reproductive system cytotoxicity, we evaluated global changes of miRNA and mRNA expression in mouse Sertoli cells following MC-LR treatment. Our results revealed that the exposure to MC-LR resulted in an altered miRNA expression profile that might be responsible for the modulation of mRNA expression. Bio-functional analysis indicated that the altered genes were involved in specific cellular processes, including cell death and proliferation. Target gene analysis suggested that junction injury in Sertoli cells exposed to MC-LR might be mediated by miRNAs through the regulation of the Sertoli cell-Sertoli cell pathway. Collectively, these findings may enhance our understanding on the modes of action of MC-LR on mouse Sertoli cells as well as the molecular mechanisms underlying the toxicity of MC-LR on the male reproductive system. - Highlights: • miRNAs were altered in Sertoli cells exposed to MC-LR. • Alerted genes were involved in different cell functions including the cell morphology. • MC-LR adversely affected Sertoli cell junction formation through the regulating miRNAs.

  18. Market values summary/December market review/current market data

    SciTech Connect (OSTI)

    1994-01-01

    This article is the December 1993 uranium market summary. During this period, there were six deals in the restricted concentrates market and none in the unrestricted market. The restricted value dropped slightly to $9.85 per pound U3O8, while the unrestricted market rose slightly to $7.00. The UF6 market was also slow, with a slight decrease in the restricted UF6 value to $31.00 and no change in the unrestricted value ($24.00). The unrestricted transaction value was $7.15 per pound U3O8, and the restricted value was $10.25. In the enrichment services market, the unrestricted SWU value remained fixed at $68.00 per SWU, while the unrestricted value increased by a dollar to $84.00 per SWU. Active uranium supply decreased, while active demand increased.

  19. Electricity Market Manipulation: How Behavioral Modeling Can Help Market Design

    SciTech Connect (OSTI)

    Gallo, Giulia

    2015-12-18

    The question of how to best design electricity markets to integrate variable and uncertain renewable energy resources is becoming increasingly important as more renewable energy is added to electric power systems. Current markets were designed based on a set of assumptions that are not always valid in scenarios of high penetrations of renewables. In a future where renewables might have a larger impact on market mechanisms as well as financial outcomes, there is a need for modeling tools and power system modeling software that can provide policy makers and industry actors with more realistic representations of wholesale markets. One option includes using agent-based modeling frameworks. This paper discusses how key elements of current and future wholesale power markets can be modeled using an agent-based approach and how this approach may become a useful paradigm that researchers can employ when studying and planning for power systems of the future.

  20. Market balances Mideast capacity

    SciTech Connect (OSTI)

    LeBlanc, L.; Redden, J.; Cornitius, T.; Tanner, R.

    1984-12-01

    Market forces will play a substantial role in energy pricing through the end of the century, but the Mideast countries are still in a commanding position in world energy supplies. The Mideast, with 55% of the world's proven crude reserves, is providing only 21% of worldwide production. This situation, brought about by political pricing in the face of sharply reduced consumption worldwide, will prolong the life of Mideast reserves. Energy importing nations, chiefly the United States, are supporting domestic production with reserves discovered during the 1979-82 period. A commanding position in this production should last through the end of this decase, after which OPEC, led by the Mideast countries, will increasingly influence energy pricing.

  1. Natural Gas Marketed Production

    U.S. Energy Information Administration (EIA) Indexed Site

    Wellhead Price Marketed Production Period: Monthly Annual Download Series History Download Series History Definitions, Sources & Notes Definitions, Sources & Notes Show Data By: Data Series Area Jan-16 Feb-16 Mar-16 Apr-16 May-16 Jun-16 View History U.S. 2,444,353 2,322,999 2,451,302 2,359,586 2,420,982 2,323,578 1973-2016 Federal Offshore Gulf of Mexico 107,121 99,600 109,645 100,355 107,005 98,896 1997-2016 Alabama NA NA NA NA NA NA 1989-2016 Alaska 30,686 28,434 29,893 26,259 27,071

  2. Clean Cities: Detroit Area Clean Cities coalition

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Corporation; the Olkonorei Integrated Pastoralist Survival Program in Tanzania, Africa; and as an instructor at the Japanese Ministry of Education in Imadate, Japan. He has...

  3. Detroit Public Lighting Department - Commercial and Industrial...

    Broader source: Energy.gov (indexed) [DOE]

    PublicLightingEnergyWis... Expiration Date 11302012 State Michigan Program Type Rebate Program Rebate Amount Light Fixtures: 2-130 Lighting Controls: 0.10-65...

  4. Detroit Street Lighting Report | Department of Energy

    Energy Savers [EERE]

    Energy Cooperation and Non-Proliferation | Department of Energy Clay Sell Touts Georgian Efforts to Advance Regional Energy Cooperation and Non-Proliferation Deputy Secretary Clay Sell Touts Georgian Efforts to Advance Regional Energy Cooperation and Non-Proliferation March 16, 2007 - 10:55am Addthis Visits National Nuclear Waste Repository in Mtskheta, Georgia TBILISI, Georgia - U.S. Deputy Secretary of Energy Clay Sell today visited the National Radioactive Waste Repository in Mtskheta,

  5. Ionizing Radiation–Inducible miR-27b Suppresses Leukemia Proliferation via Targeting Cyclin A2

    SciTech Connect (OSTI)

    Wang, Bo; Li, Dongping; Kovalchuk, Anna; Litvinov, Dmitry; Kovalchuk, Olga

    2014-09-01

    Purpose: Ionizing radiation is a common carcinogen that is important for the development of leukemia. However, the underlying epigenetic mechanisms remain largely unknown. The goal of the study was to explore microRNAome alterations induced by ionizing radiation (IR) in murine thymus, and to determine the role of IR-inducible microRNA (miRNA/miR) in the development of leukemia. Methods and Materials: We used the well-established C57BL/6 mouse model and miRNA microarray profiling to identify miRNAs that are differentially expressed in murine thymus in response to irradiation. TIB152 human leukemia cell line was used to determine the role of estrogen receptor–α (ERα) in miR-27b transcription. The biological effects of ectopic miR-27b on leukemogenesis were measured by western immunoblotting, cell viability, apoptosis, and cell cycle analyses. Results: Here, we have shown that IR triggers the differential expression of miR-27b in murine thymus tissue in a dose-, time- and sex-dependent manner. miR-27b was significantly down-regulated in leukemia cell lines CCL119 and TIB152. Interestingly, ERα was overexpressed in those 2 cell lines, and it was inversely correlated with miR-27b expression. Therefore, we used TIB152 as a model system to determine the role of ERα in miR-27b expression and the contribution of miR-27b to leukemogenesis. β-Estradiol caused a rapid and transient reduction in miR-27b expression reversed by either ERα-neutralizing antibody or ERK1/2 inhibitor. Ectopic expression of miR-27b remarkably suppressed TIB152 cell proliferation, at least in part, by inducing S-phase arrest. In addition, it attenuated the expression of cyclin A2, although it had no effect on the levels of PCNA, PPARγ, CDK2, p21, p27, p-p53, and cleaved caspase-3. Conclusion: Our data reveal that β-estradiol/ERα signaling may contribute to the down-regulation of miR-27b in acute leukemia cell lines through the ERK1/2 pathway, and that miR-27b may function as a tumor

  6. miR-208-3p promotes hepatocellular carcinoma cell proliferation and invasion through regulating ARID2 expression

    SciTech Connect (OSTI)

    Yu, Peng; Wu, Dingguo; You, Yu; Sun, Jing; Lu, Lele; Tan, Jiaxing; Bie, Ping

    2015-08-15

    MicroRNAs (miRNAs) are small non-coding RNAs that negatively regulate gene expression at post-transcriptional level. miRNA dysregulation plays a causal role in cancer progression. In this study, miR-208-3p was highly expressed and directly repressed ARID2 expression. As a result, ARID2 expression in hepatocellular carcinoma (HCC) was decreased. In vitro, miR-208-3p down-regulation and ARID2 over-expression elicited similar inhibitory effects on HCC cell proliferation and invasion. In vivo test results revealed that miR-208-3p down-regulation inhibited HCC tumorigenesis in Hep3B cells. Moreover, ARID2 was possibly a downstream element of transforming growth factor beta1 (TGFβ1)/miR-208-3p/ARID2 regulatory pathway. These findings suggested that miR-208-3p up-regulation is associated with HCC cell progression and may provide a new target for liver cancer treatment. - Highlights: • miR-208-3p was highly expressed and directly repressed the expression of ARID2 in HCC. • miR-208-3p contributed to HCC cell progression both in vitro and in vivo. • Over-expression of ARID2 inhibited the HCC cell proliferation and invasion. • Restoration of ARID2 partly reversed the the effect of miR-208-3p down-regulation on HCC cells. • Newly regulatory pathway: miR-208-3p mediated the repression of ARID2 by TGFβ1 in HCC cells.

  7. Curcumin inhibits oral squamous cell carcinoma SCC-9 cells proliferation by regulating miR-9 expression

    SciTech Connect (OSTI)

    Xiao, Can; Wang, Lili; Zhu, Lifang; Zhang, Chenping; Zhou, Jianhua

    2014-11-28

    Highlights: • miR-9 expression level was significantly decreased in OSCC tissues. • Curcumin significantly inhibited SCC-9 cells proliferation. • miR-9 mediates the inhibition of SCC-9 proliferation by curcumin. • Curcumin suppresses Wnt/β-catenin signaling in SCC-9 cells. • miR-9 mediates the suppression of Wnt/β-catenin signaling by curcumin. - Abstract: Curcumin, a phytochemical derived from the rhizome of Curcuma longa, has shown anticancer effects against a variety of tumors. In the present study, we investigated the effects of curcumin on the miR-9 expression in oral squamous cell carcinoma (OSCC) and explored the potential relationships between miR-9 and Wnt/β-catenin pathway in curcumin-mediated OSCC inhibition in vitro. As the results shown, the expression levels of miR-9 were significantly lower in clinical OSCC specimens than those in the adjacent non-tumor tissues. Furthermore, our results indicated that curcumin inhibited OSCC cells (SCC-9 cells) proliferation through up-regulating miR-9 expression, and suppressing Wnt/β-catenin signaling by increasing the expression levels of the GSK-3β, phosphorylated GSK-3β and β-catenin, and decreasing the cyclin D1 level. Additionally, the up-regulation of miR-9 by curcumin in SCC-9 cells was significantly inhibited by delivering anti-miR-9 but not control oligonucleotides. Downregulation of miR-9 by anti-miR-9 not only attenuated the growth-suppressive effects of curcumin on SCC-9 cells, but also re-activated Wnt/β-catenin signaling that was inhibited by curcumin. Therefore, our findings would provide a new insight into the use of curcumin against OSCC in future.

  8. miR-339-5p inhibits alcohol-induced brain inflammation through regulating NF-κB pathway

    SciTech Connect (OSTI)

    Zhang, Yu; Wei, Guangkuan; Di, Zhiyong; Zhao, Qingjie

    2014-09-26

    Graphical abstract: - Highlights: • Alcohol upregulates miR-339-5p expression. • miR-339-5p inhibits the NF-kB pathway. • miR-339-5p interacts with and blocks activity of IKK-beat and IKK-epsilon. • miR-339-5p modulates IL-1β, IL-6 and TNF-α. - Abstract: Alcohol-induced neuroinflammation is mediated by the innate immunesystem. Pro-inflammatory responses to alcohol are modulated by miRNAs. The miRNA miR-339-5p has previously been found to be upregulated in alcohol-induced neuroinflammation. However, little has been elucidated on the regulatory functions of this miRNA in alcohol-induced neuroinflammation. We investigated the function of miR-339-5p in alcohol exposed brain tissue and isolated microglial cells using ex vivo and in vitro techniques. Our results show that alcohol induces transcription of miR 339-5p, IL-6, IL-1β and TNF-α in mouse brain tissue and isolated microglial cells by activating NF-κB. Alcohol activation of NF-κB allows for nuclear translocation of the NF-κB subunit p65 and expression of pro-inflammatory mediators. miR-339-5p inhibited expression of these pro-inflammatory factors through the NF-κB pathway by abolishing IKK-β and IKK-ε activity.

  9. Northeastern Summer Electricity Market Alert

    Reports and Publications (EIA)

    2013-01-01

    The National Weather Service declared an excessive-heat warning for much of the Mid-Atlantic and northeastern United States, including major electric markets covering Philadelphia, Boston, Washington, D.C., and New York City. This report highlights the wholesale electricity market activity occurring in response to the higher-than-normal electricity demand caused by the heat wave.

  10. Port Huron, MI Liquefied Natural Gas Exports to Canada (Million Cubic Feet)

    U.S. Energy Information Administration (EIA) Indexed Site

    to Canada (Million Cubic Feet) Port Huron, MI Liquefied Natural Gas Exports to Canada (Million Cubic Feet) Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2013 1 2014 1 1 1 1 2 1 1 1 1 1 2015 1 1 1 1 1 - = No Data Reported; -- = Not Applicable; NA = Not Available; W = Withheld to avoid disclosure of individual company data. Release Date: 08/31/2016 Next Release Date: 09/30/2016 Referring Pages: U.S. Liquefied Natural Gas Exports by Point of Exit Port Huron, MI Natural Gas Exports to Canad

  11. EA-280 Direct Energy Marketing Inc | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Direct Energy Marketing Inc EA-280 Direct Energy Marketing Inc Order authorizing Direct Energy Marketing Inc to export electric energy to Canada. EA-280 Direct Energy Marketing ...

  12. EA-148-A Aquila Marketing Corporation | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    8-A Aquila Marketing Corporation EA-148-A Aquila Marketing Corporation Order authorizing Aquila Marketing Corporation to export electric energy to Canada. EA-148-A Aquila Marketing ...

  13. Noncommercial Trading in the Energy Futures Market

    Reports and Publications (EIA)

    1996-01-01

    How do futures markets affect spot market prices? This is one of the most pervasive questions surrounding futures markets, and it has been analyzed in numerous ways for many commodities.

  14. Market values summary/February market review/current market data

    SciTech Connect (OSTI)

    1995-03-01

    This article is the February 1995 uranium market summary. In the natural uranium and concentrates market, there were 10 deals, and the restricted value moved upward to $10.40. The unrestricted value remained fixed at $7.25. In the UF6 market, there were two deals in the restricted market, and the restricted value rose to $32.75 per kgU as UF6. The unrestricted value remained at $25.00. The restricted transaction value rose to $9.75, and the unrestricted value rose to $7.15. In the enrichment services market, there were three deals. The restricted SWU value rose to $90 per SWU, and the unrestricted value rose to $75 per SWU. Active uranium supply and active uranium demand dropped this reporting period.

  15. Market values summary/April market review/current market data

    SciTech Connect (OSTI)

    1994-05-01

    This article is the April 1994 uranium market summary. The near-term market was slow, with three near-term deals for concentrates and none for UF6. This was reflected in the decline of the concentrates restricted value $9.30 per pound U3O8 and the UF6 restricted value to $29.75 per kgU as UF6. In each market, the unrestricted value remained unchanged at $7.00 and $24.50 due to the lack of trades in the unrestricted market. Transaction values in both the restricted and unrestricted market were constant at $9.45 and $7.05 per pound U3O8. The restricted SWU value rose a dollar to $88 per SWU, and the unrestricted SWU value remained steady at $67 per SWU. Active demand continued to decrease, while active supply increased.

  16. MicroRNAs expression in ox-LDL treated HUVECs: MiR-365 modulates apoptosis and Bcl-2 expression

    SciTech Connect (OSTI)

    Qin, Bing; Xiao, Bo; Liang, Desheng; Xia, Jian; Li, Ye; Yang, Huan

    2011-06-24

    Highlights: {yields} We evaluated the role of miRNAs in ox-LDL induced apoptosis in ECs. {yields} We found 4 up-regulated and 11 down-regulated miRNAs in apoptotic ECs. {yields} Target genes of the dysregulated miRNAs regulate ECs apoptosis and atherosclerosis. {yields} MiR-365 promotes ECs apoptosis via suppressing Bcl-2 expression. {yields} MiR-365 inhibitor alleviates ECs apoptosis induced by ox-LDL. -- Abstract: Endothelial cells (ECs) apoptosis induced by oxidized low-density lipoprotein (ox-LDL) is thought to play a critical role in atherosclerosis. MicroRNAs (miRNAs) are a class of noncoding RNAs that posttranscriptionally regulate the expression of genes involved in diverse cell functions, including differentiation, growth, proliferation, and apoptosis. However, whether miRNAs are associated with ox-LDL induced apoptosis and their effect on ECs is still unknown. Therefore, this study evaluated potential miRNAs and their involvement in ECs apoptosis in response to ox-LDL stimulation. Microarray and qRT-PCR analysis performed on human umbilical vein endothelial cells (HUVECs) exposed to ox-LDL identified 15 differentially expressed (4 up- and 11 down-regulated) miRNAs. Web-based query tools were utilized to predict the target genes of the differentially expressed miRNAs, and the potential target genes were classified into different function categories with the gene ontology (GO) term and KEGG pathway annotation. In particular, bioinformatics analysis suggested that anti-apoptotic protein B-cell CLL/lymphoma 2 (Bcl-2) is a target gene of miR-365, an apoptomir up-regulated by ox-LDL stimulation in HUVECs. We further showed that transfection of miR-365 inhibitor partly restored Bcl-2 expression at both mRNA and protein levels, leading to a reduction of ox-LDL-mediated apoptosis in HUVECs. Taken together, our findings indicate that miRNAs participate in ox-LDL-mediated apoptosis in HUVECs. MiR-365 potentiates ox-LDL-induced ECs apoptosis by regulating the

  17. Market Analysis Reports | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Information Resources » Technical Publications » Market Analysis Reports Market Analysis Reports Reports about fuel cell and hydrogen technology market analysis are provided in these publication categories: Fuel Cell Technologies Office Market Reports Pathways to Commercial Success Business Case for Fuel Cells State of the States General Fuel Cell Technologies Office Market Reports 2014 Fuel Cell Technologies Market Report (Fuel Cell Technologies Office, October 2015) 2013 Fuel Cell

  18. Technology to Market | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Technology to Market Technology to Market The SunShot Initiative's Technology to Market subprogram builds on SunShot's record of moving groundbreaking and early-stage technologies and business models to the market. Technology to Market targets two known funding gaps: those that occur at the prototype commercialization stage and those at the commercial scale-up stage. All Technology to Market programs are tightly structured to ensure that recipients commercialize the funded technology and achieve

  19. Career Map: Power Marketer | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Marketer Career Map: Power Marketer A smiling male power marketer stands outside of a building with numerous windows that reflect the landscape. Power Marketer Position Title Power Marketer Alternate Title(s) n/a Education & Training Level Advanced, Bachelors required, prefer graduate degree Education & Training Level Description Power marketers typically need a degree in finance or engineering. Entry level positions as an analyst may only require a bachelor's degree, while advanced

  20. EA-1690: A123 Systems, Inc., Automotive-Class Lithium-Ion Battery

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Production Facilities near Detroit, MI | Department of Energy 0: A123 Systems, Inc., Automotive-Class Lithium-Ion Battery Production Facilities near Detroit, MI EA-1690: A123 Systems, Inc., Automotive-Class Lithium-Ion Battery Production Facilities near Detroit, MI April 1, 2010 EA-1690: Final Environmental Assessment For a Loan and Grant to A123 Systems, Inc., for Vertically Integrated Mass Production of Automotive-Class Lithium-Ion Batteries April 20, 2010 EA-1690: Finding of No

  1. MiRNA-125a-5p inhibits glioblastoma cell proliferation and promotes cell differentiation by targeting TAZ

    SciTech Connect (OSTI)

    Yuan, Jian; Xiao, Gelei; Peng, Gang; Liu, Dingyang; Wang, Zeyou; Liao, Yiwei; Liu, Qing; Wu, Minghua; Yuan, Xianrui

    2015-02-06

    Highlights: • Expression of miR-125a-5p is inversely correlated with that of TAZ in glioma cells. • MiR-125a-5p represses TAZ expression in glioma cells. • MiR-125a-5p directly targets the 3′ UTR of TAZ mRNA and promotes its degradation. • MiR-125a-5p represses CTGF and survivin via TAZ, and inhibits glioma cell growth. • MiR-125a-5p inhibits the stem cell features of HFU-251 MG cells. - Abstract: Glioblastoma (GBM) is the most lethal brain tumor due to the resistance to conventional therapies, such as radiotherapy and chemotherapy. TAZ, an important mediator of the Hippo pathway, was found to be up-regulated in diverse cancers, including in GBM, and plays important roles in tumor initiation and progression. However, little is known about the regulation of TAZ expression in tumors. In this study, we found that miR-125a-5p is an important regulator of TAZ in glioma cells by directly targeting the TAZ 3′ UTR. MiR-125a-5p levels are inversely correlated with that of TAZ in normal astrocytes and a panel of glioma cell lines. MiR-125a-5p represses the expression of TAZ target genes, including CTGF and survivin, and inhibits cell proliferation and induces the differentiation of GBM cells; whereas over-expression of TAZ rescues the effects of miR-125a-5p. This study revealed a mechanism for TAZ deregulation in glioma cells, and also demonstrated a tumor suppressor role of miR-125a-5p in glioblastoma cells.

  2. Petroleum marketing monthly, May 1994

    SciTech Connect (OSTI)

    Not Available

    1994-05-26

    The Petroleum Marketing Monthly (PMM) provides information and statistical data on a variety of crude oils and refined petroleum products. The publication presents statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the f.o.b. and landed cost of imported crude oil, petroleum product sales data include motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane. The Petroleum Marketing Division, Office of Oil and Gas, Energy Information Administration ensures the accuracy, quality, and confidentiality of the published data in the Petroleum Marketing Monthly.

  3. 2008 Solar Technologies Market Report

    SciTech Connect (OSTI)

    none,

    2010-01-29

    The focus of this report is the U.S. solar electricity market, including photovoltaic (PV) and concentrating solar power (CSP) technologies. The report is organized into five chapters. Chapter 1 provides an overview of global and U.S. installation trends. Chapter 2 presents production and shipment data, material and supply chain issues, and solar industry employment trends. Chapter 3 presents cost, price, and performance trends. Chapter 4 discusses policy and market drivers such as recently passed federal legislation, state and local policies, and developments in project financing. Chapter 5 provides data on private investment trends and near-term market forecasts.

  4. Final Draft Strategic Marketing Plan.

    SciTech Connect (OSTI)

    United States. Bonneville Power Administration.

    1994-02-01

    The Bonneville Power Administration (BPA) has developed a marketing plan to define how BPA can be viable and competitive in the future, a result important to BPA`s customers and constituents. The Marketing Plan represents the preferred customer outcomes, marketplace achievements, and competitive advantage required to accomplish the Vision and the Strategic Business Objectives of the agency. The Marketing Plan contributes to successful implementation of BPA`s Strategic Business Objectives (SBOs) by providing common guidance to organizations and activities throughout the agency responsible for (1) planning, constructing, operating, and maintaining the Federal Columbia River Power System; (2) conducting business with BPA`s customers; and (3) providing required internal support services.

  5. PROJECT PROFILE: Extensible Energy (Solar Market Pathways) |...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Extensible Energy (Solar Market Pathways) PROJECT PROFILE: Extensible Energy (Solar Market Pathways) Title: High-Value Integrated Community Solar Project Extensible Energy logo.jpg ...

  6. Market Transformation: Fuel Cell Early Adoption (Presentation...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Fuel Cell Pre-Solicitation Workshop January 23, 2008 Pete Devlin Manager, Market ... Early markets in stationary, portable, and niche applications will lower cost and ...

  7. 2009 Wind Technologies Market Report Summary Presentation

    SciTech Connect (OSTI)

    Ryan Wiser, Mark Bolinger

    2010-08-01

    This is a Powerpoint presentation on the 2009 Wind Technologies Market Report, which covers the major developments in the U.S. wind energy market in 2009.

  8. NRG Power Marketing LLC | Open Energy Information

    Open Energy Info (EERE)

    Marketing LLC Jump to: navigation, search Name: NRG Power Marketing LLC Address: 211 Carnegie Center Place: Princeton, New Jersey Country: United States Phone Number: 609-524-4500...

  9. Thomas Jefferson National Accelerator Facility Technology Marketing...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Thomas Jefferson National Accelerator Facility Technology Marketing Summaries Here you'll find marketing summaries for technologies available for licensing from the Thomas...

  10. Tractebel Energy Marketing Inc | Open Energy Information

    Open Energy Info (EERE)

    Tractebel Energy Marketing Inc Jump to: navigation, search Name: Tractebel Energy Marketing Inc Address: 1177 West Loop South Suite 800 Place: Houston, TX Zip: 77027 Phone Number:...

  11. Ameren Energy Marketing | Open Energy Information

    Open Energy Info (EERE)

    Marketing Jump to: navigation, search Name: Ameren Energy Marketing Place: Missouri Service Territory: Missouri Phone Number: 1 800-552-7583 Website: www.ameren.commissouri...

  12. Rainbow Energy Marketing Corp | Open Energy Information

    Open Energy Info (EERE)

    Energy Marketing Corp Jump to: navigation, search Name: Rainbow Energy Marketing Corp Place: North Dakota Phone Number: (701) 222-2290 Website: www.rainbowenergy.com Facebook:...

  13. Enertech Marketing Services | Open Energy Information

    Open Energy Info (EERE)

    Enertech Marketing Services Jump to: navigation, search Name: Enertech Marketing Services Place: Bangalore, Karnataka, India Zip: 560041 Sector: Services, Solar Product: Enertech...

  14. Green Power Marketing | Open Energy Information

    Open Energy Info (EERE)

    Green Power Marketing Jump to: navigation, search Gearbox installation at Xcel Energy's Ponnequin Wind Farm in Colorado. Photo from Jeroen van Dam, NREL 19257 Green power marketing...

  15. SLAC National Accelerator Laboratory Technology Marketing Summaries...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    SLAC National Accelerator Laboratory Technology Marketing Summaries Here you'll find marketing summaries for technologies available for licensing from the SLAC National Accelerator...

  16. Ameren Energy Marketing (Illinois) | Open Energy Information

    Open Energy Info (EERE)

    Marketing (Illinois) Jump to: navigation, search Name: Ameren Energy Marketing Place: Illinois References: EIA Form EIA-861 Final Data File for 2010 - File220101 EIA Form 861...

  17. Badger Power Marketing Auth | Open Energy Information

    Open Energy Info (EERE)

    Power Marketing Auth Jump to: navigation, search Name: Badger Power Marketing Auth Place: Wisconsin Phone Number: (715) 526-2920 Facebook: https:www.facebook.compages...

  18. Wolverine Power Marketing Coop | Open Energy Information

    Open Energy Info (EERE)

    Power Marketing Coop Jump to: navigation, search Name: Wolverine Power Marketing Coop Place: Michigan Phone Number: 1.877.907.9762 Website: www.wpmc.coop Outage Hotline:...

  19. Transmission Reliability Program 2015 Reliability & Markets Peer...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Program 2015 Reliability & Markets Peer Review Materials Available Transmission Reliability Program 2015 Reliability & Markets Peer Review Materials Available September 16, 2015 -...

  20. 2012 Wind Technologies Market Report Presentation

    Broader source: Energy.gov [DOE]

    Presentation that summarizes the annual Wind Technologies Market Report, which summarizes key trends in the 2012 U.S. wind power market.

  1. Carbon Market Brasil Consulting | Open Energy Information

    Open Energy Info (EERE)

    Market Brasil Consulting Jump to: navigation, search Name: Carbon Market Brasil Consulting Place: Sao Paulo, Brazil Zip: 04120-070 Sector: Carbon Product: Brazil-based carbon...

  2. Carbon Markets Global Ltd | Open Energy Information

    Open Energy Info (EERE)

    Markets Global Ltd Jump to: navigation, search Name: Carbon Markets Global Ltd Place: London, United Kingdom Zip: NW4 2HT Product: Assist project originators develop and finance...

  3. Fact Sheet: 2013 Distributed Wind Market Report

    Office of Energy Efficiency and Renewable Energy (EERE)

    This fact sheet summarizes findings from the forthcoming 2013 Distributed Wind Market Report, offering a snapshot of the distributed wind market based on 2013 data.

  4. Ecology Action: Small Market Advanced Retrofit Transformation...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Ecology Action: Small Market Advanced Retrofit Transformation Program (SMART) Ecology Action: Small Market Advanced Retrofit Transformation Program (SMART) Ecology Action: Small ...

  5. Princeton Plasma Physics Laboratory Technology Marketing Summaries...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Princeton Plasma Physics Laboratory Technology Marketing Summaries Here you'll find marketing summaries for technologies available for licensing from the Princeton Plasma Physics ...

  6. 2013 Wind Technologies Market Report Presentation | Department...

    Broader source: Energy.gov (indexed) [DOE]

    & Publications 2012 Wind Technologies Market Report Presentation 2013 Wind Technologies Market Report Economic Environment 0 Anirban Basu, Chairman & CEO, Sage Policy Group, Inc....

  7. NREL: Transmission Grid Integration - Wholesale Electricity Market...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Wholesale Electricity Market Operations Researchers at NREL are studying wholesale electricity market operations to understand how they currently maximize competition, efficiency, ...

  8. Solar Energy Market Forecast | Open Energy Information

    Open Energy Info (EERE)

    Market Forecast Jump to: navigation, search Tool Summary LAUNCH TOOL Name: Solar Energy Market Forecast AgencyCompany Organization: United States Department of Energy Sector:...

  9. Marketing & Driving Demand: Social Media Tools & Strategies ...

    Office of Environmental Management (EM)

    Marketing & Driving Demand: Social Media Tools & Strategies - January 16, 2011 (Text Version) Marketing & Driving Demand: Social Media Tools & Strategies - January 16, 2011 (Text...

  10. NREL Market Analysis | Open Energy Information

    Open Energy Info (EERE)

    TOOL Name: NREL Market analysis AgencyCompany Organization: National Renewable Energy Laboratory Sector: Energy Topics: Market analysis Website: www.nrel.govanalysis...

  11. Energy Merchant Marketing EMM | Open Energy Information

    Open Energy Info (EERE)

    Name: Energy Merchant Marketing (EMM) Place: New York, New York Zip: 10022 Product: Biodiesel producer. References: Energy Merchant Marketing (EMM)1 This article is a stub....

  12. Fact Sheet: 2012 Distributed Wind Market Report

    SciTech Connect (OSTI)

    Alice Orrell, Bret Barker

    2013-04-06

    This fact sheet summarizes findings from the forthcoming 2012 Distributed Wind Market Report, offering a snapshot of the distributed wind market based on 2012 data.

  13. Environmental Markets Association | Open Energy Information

    Open Energy Info (EERE)

    20005 Product: The Environmental Markets Association (EMA), an international nonprofit trade association, was originally formed in 1997 to promote market-based trading solutions...

  14. International Market Opportunities in Bioenergy: Leveraging U...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    International Market Opportunities in Bioenergy: Leveraging U.S. Government Resources Breakout Session 3C-Fostering Technology Adoption III: International Market Opportunities in ...

  15. Marketing and Communications Plan | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Communications Plan Marketing and Communications Plan This is a document from Energy ... PDF icon Marketing and Communications Plan More Documents & Publications Sonoma County ...

  16. Gamesa Wind to Market | Open Energy Information

    Open Energy Info (EERE)

    Wind energy Product: Represents the interests of wind project owner clients in the Spanish electricity market References: Gamesa Wind to Market1 This article is a stub. You...

  17. International Market Opportunities in Bioenergy: Leveraging U...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    International Market Opportunities in Bioenergy: Leveraging U.S. Government Resources International Market Opportunities in Bioenergy: Leveraging U.S. Government Resources Breakout ...

  18. 2009 Wind Technologies Market Report Executive Summary

    SciTech Connect (OSTI)

    Bolinger, Mark; Wiser, Ryan

    2010-08-01

    This is the executive summary for the 2009 Wind Technologies Market Report, which covers the major developments in the U.S. wind energy market in 2009.

  19. Performance, Market and Manufacturing Constraints relevant to...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Performance, Market and Manufacturing Constraints relevant to the Industrialization of Thermoelectric Devices Market pricing of thermoelectric raw materials and processing, cost of ...

  20. Natural Gas and Hydrogen Infrastructure Opportunities: Markets...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Opportunities: Markets and Barriers to Growth Natural Gas and Hydrogen Infrastructure Opportunities: Markets and Barriers to Growth Presentation by Matt Most, Encana Natural Gas, ...

  1. DOE Zero Energy Ready Home Case Study: Cobblestone Homes, Midland, MI

    Broader source: Energy.gov [DOE]

    Case study of a DOE Zero Energy Ready home in Midland, MI, that scored HERS 49 without PV or HERS 44 with 1.4 kW of PV. The custom home served as a prototype and energy efficiency demonstration...

  2. The NuMI proton beam at Fermilab successes and challenges

    SciTech Connect (OSTI)

    Childress, S.; /Fermilab

    2008-11-01

    The NuMI beam at Fermilab has delivered over 5 x 10{sup 20} 120 GeV protons to the neutrino production target since the start for MINOS [1] neutrino oscillation experiment operation in 2005. We report on proton beam commissioning and operation status, including successes and challenges with this beam.

  3. Markets for concentrating solar power

    SciTech Connect (OSTI)

    Not Available

    1998-04-01

    The report describes the markets for concentrating solar power. As concentrating solar power technologies advance into the early stages of commercialization, their economic potential becomes more sharply defined and increasingly tangible.

  4. 2013 Distributed Wind Market Report

    SciTech Connect (OSTI)

    Orrell, Alice C.; Rhoads-Weaver, H. E.; Flowers, Larry T.; Gagne, Matthew N.; Pro, Boyd H.; Foster, Nikolas AF

    2014-08-20

    The purpose of this report is to quantify and summarize the 2013 U.S. distributed wind market to help plan and guide future investments and decisions by industry stakeholders, utilities, state and federal agencies, and other interested parties.

  5. Energy Management and Marketing Specialist

    Broader source: Energy.gov [DOE]

    (See Frequently Asked Questions for more information). Where would I be working? Western Area Power Administration Sierra Nevada Region Power Marketing Merchant Real Time N6500 114 Parkshore Drive...

  6. 2012 Vehicle Technologies Market Report

    SciTech Connect (OSTI)

    Davis, Stacy Cagle; Diegel, Susan W; Boundy, Robert Gary

    2013-03-01

    The Oak Ridge National Laboratory s Center for Transportation Analysis developed and published the first Vehicle Technologies Market Report in 2008. Three editions of the report have been published since that time. This 2012 report details the major trends in U.S. light vehicle and medium/heavy truck markets as well as the underlying trends that caused them. The opening section on Energy and Economics discusses the role of transportation energy and vehicle markets on a national scale. The following section examines light-duty vehicle use, markets, manufacture, and supply chains. The discussion of medium and heavy trucks offers information on truck sales and fuel use. The technology section offers information on alternative fuel vehicles and infrastructure, and the policy section concludes with information on recent, current, and near-future Federal policies like the Corporate Average Fuel Economy standards.

  7. 2015 Uranium Marketing Annual Report

    U.S. Energy Information Administration (EIA) Indexed Site

    Uranium Marketing Annual Report Release Date: May 24, 2016 Next Release Date: May 2017 Deliveries 2011 2012 2013 2014 2015 Purchases 1,668 1,194 W 410 2,702 Weighted-average price ...

  8. 2015 Uranium Marketing Annual Report

    U.S. Energy Information Administration (EIA) Indexed Site

    7 2015 Uranium Marketing Annual Report Release Date: May 24, 2016 Next Release Date: May 2017 Table S3b. Weighted-average price of foreign purchases and foreign sales by U.S. ...

  9. Rooftop Photovoltaics Market Penetration Scenarios

    SciTech Connect (OSTI)

    Paidipati, J.; Frantzis, L.; Sawyer, H.; Kurrasch, A.

    2008-02-01

    The goal of this study was to model the market penetration of rooftop photovoltaics (PV) in the United States under a variety of scenarios, on a state-by-state basis, from 2007 to 2015.

  10. Step 1: Assess the Market

    Broader source: Energy.gov [DOE]

    To establish meaningful program goals and objectives and to create program offerings that will resonate with your community, you will first need to understand the local market for energy efficiency:

  11. National Symposium on Market Transformation

    Broader source: Energy.gov [DOE]

    Hosted by the American Council for an Energy-Efficient Economy (ACEEE) and the Consortium for Energy Efficiency (CEE), this three-day conference features speakers covering topics within the scope of market transformation.

  12. Preliminary Process and Market Evaluation

    Broader source: Energy.gov [DOE]

    Preliminary Process and Market Evaluation, from a team of evaluators, independent of the BBNP program, with whom DOE contracted to assess the performance of BBNP and identify lessons learned.

  13. MiR-18a regulates the proliferation, migration and invasion of human glioblastoma cell by targeting neogenin

    SciTech Connect (OSTI)

    Song, Yichen; Wang, Ping; Zhao, Wei; Yao, Yilong; Liu, Xiaobai; Ma, Jun; Xue, Yixue; Liu, Yunhui

    2014-05-15

    MiR-17-92 cluster has recently been reported as an oncogene in some tumors. However, the association of miR-18a, an important member of this cluster, with glioblastoma remains unknown. Therefore, this study aims to investigate the expression of miR-18a in glioblastoma and its role in biological behavior of U87 and U251 human glioblastoma cell lines. Quantitative RT-PCR results showed that miR-18a was highly expressed in glioblastoma tissues and U87 and U251 cell lines compared with that in human brain tissues and primary normal human astrocytes, and the expression levels were increased along with the rising pathological grades of glioblastoma. Neogenin was identified as the target gene of miR-18a by dual-luciferase reporter assays. RT-PCR and western blot results showed that its expression levels were decreased along with the rising pathological grades of glioblastoma. Inhibition of miR-18a expression was established by transfecting exogenous miR-18a inhibitor into U87 and U251 cells, and its effects on the biological behavior of glioblastoma cells were studied using CCK-8 assay, transwell assay and flow cytometry. Inhibition of miR-18a expression in U87 and U251 cells significantly up-regulated neogenin, and dramatically suppressed the abilities of cell proliferation, migration and invasion, induced cell cycle arrest and promoted cellular apoptosis. Collectively, these results suggest that miR-18a may regulate biological behavior of human glioblastoma cells by targeting neogenin, and miR-18a can serve as a potential target in the treatment of glioblastoma. - Highlights: • MiR-18a was highly expressed in glioblastoma tissues and U87 and U251 cell lines. • Neogenin was identified as the target gene of miR-18a. • Neogenin expressions were decreased along with the rising pathological grades of glioblastoma. • Inhibition of miR-18a suppressed biological behavior of glioma cells by up-regulating neogenin.

  14. Market values summary/October market review/current market data

    SciTech Connect (OSTI)

    1993-11-01

    This article is the October 1993 uranium market summary. In spite of the substantial quantity of material that moved through the unrestricted market during this period, the unrestricted exchange value remained constant at $6.90 per pound U3O8, and the unrestricted value dipped to $10.15. There were four deals in the concentrates market during this period. Both the restricted and the unrestricted UF6 values remained constant at $31.75 and $24.75 per kgU as UF6 respectively, as did the restricted and unrestricted SWU values ($82 and $68 respectively). Active supply increased, while active demand decreased.

  15. WINDExchange: Wind Energy Market Sectors

    Wind Powering America (EERE)

    Market Sectors Printable Version Bookmark and Share Utility-Scale Wind Distributed Wind Motivations for Buying Wind Power Buying Wind Power Selling Wind Power Wind Energy Market Sectors U.S. power plants generate electricity for homes, factories, and businesses from a variety of resources, including coal, hydro, natural gas, nuclear, petroleum, and (non-hydro) renewable resources such as wind and solar energy. This power generation mix varies significantly across the country depending on

  16. Market Challenges | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    SSL Basics » Market Challenges Market Challenges Solid-state lighting (SSL) has the potential to significantly reduce lighting energy use and slash greenhouse-gas emissions. By 2030, DOE estimates that SSL could potentially cut national lighting electricity use nearly in half, but a number of challenges stand in the way of achieving the full energy saving potential of SSL. Although SSL products now appear to be competitive in many applications-from bulbs sold in grocery stores to street lights

  17. PADD 5 Transportation Fuels Markets

    U.S. Energy Information Administration (EIA) Indexed Site

    PADD 5 Transportation Fuels Markets September 2015 Independent Statistics & Analysis www.eia.gov U.S. Department of Energy Washington, DC 20585 U.S. Energy Information Administration | PADD 5 Transportation Fuels Markets i This report was prepared by the U.S. Energy Information Administration (EIA), the statistical and analytical agency within the U.S. Department of Energy. By law, EIA's data, analyses, and forecasts are independent of approval by any other officer or employee of the United

  18. Electricity market players subgroup report

    SciTech Connect (OSTI)

    Borison, A.

    1990-03-01

    The purpose of this study is to examine competition in the electric power industry from an ``industrial organization`` point of view. The remainder of this report is organized as follows. Chapter 2 describes the ``industrial organization`` approach used to analyze the electric power market. Industrial organization emphasizes specific market performance criteria, and the impact of market structure and behavior on performance. Chapter 3 identifies the participants in the electric power market, grouped primarily into regulated producers, unregulated producers, and consumers. Chapter 4 describes the varieties of electric power competition, organized along two dimensions: producer competition and consumer competition. Chapters 5 and 6 identify the issues raised by competition along the two dimensions. These issues include efficiency, equity, quality, and stability. Chapters 7 through 9 describe market structure, behavior and performance in three competitive scenarios: minimum competition, maximum competition, and moderate competition. Market structure, behavior and performance are discussed, and the issues raised in Chapters 5 and 6 are discussed in detail. Chapter 10 provides conclusions about ``winners and losers`` and identifies issues that require further study.

  19. Electricity market players subgroup report

    SciTech Connect (OSTI)

    Borison, A.

    1990-03-01

    The purpose of this study is to examine competition in the electric power industry from an industrial organization'' point of view. The remainder of this report is organized as follows. Chapter 2 describes the industrial organization'' approach used to analyze the electric power market. Industrial organization emphasizes specific market performance criteria, and the impact of market structure and behavior on performance. Chapter 3 identifies the participants in the electric power market, grouped primarily into regulated producers, unregulated producers, and consumers. Chapter 4 describes the varieties of electric power competition, organized along two dimensions: producer competition and consumer competition. Chapters 5 and 6 identify the issues raised by competition along the two dimensions. These issues include efficiency, equity, quality, and stability. Chapters 7 through 9 describe market structure, behavior and performance in three competitive scenarios: minimum competition, maximum competition, and moderate competition. Market structure, behavior and performance are discussed, and the issues raised in Chapters 5 and 6 are discussed in detail. Chapter 10 provides conclusions about winners and losers'' and identifies issues that require further study.

  20. miR-7 and miR-218 epigenetically control tumor suppressor genes RASSF1A and Claudin-6 by targeting HoxB3 in breast cancer

    SciTech Connect (OSTI)

    Li, Qiaoyan; Zhu, Fufan; Chen, Puxiang

    2012-07-20

    Highlights: Black-Right-Pointing-Pointer Both miR-7 and miR-218 down-regulates HoxB3 expression by targeting the 3 Prime -UTR of HoxB3 mRNA. Black-Right-Pointing-Pointer A reverse correlation between the levels of endogenous miR-7, miR218 and HoxB3 expression. Black-Right-Pointing-Pointer Epigenetic changes involve in the reactivation of HoxB3. Black-Right-Pointing-Pointer Both miRNAs inhibits the cell cycle and clone formation of breast cancer cells. -- Abstract: Many microRNAs have been implicated as key regulators of cellular growth and differentiation and have been found to dysregulate proliferation in human tumors, including breast cancer. Cancer-linked microRNAs also alter the epigenetic landscape by way of DNA methylation and post-translational modifications of histones. Aberrations in Hox gene expression are important for oncogene or tumor suppressor during abnormal development and malignancy. Although recent studies suggest that HoxB3 is critical in breast cancer, the putative role(s) of microRNAs impinging on HoxB3 is not yet fully understood. In this study, we found that the expression levels of miR-7 and miR-218 were strongly and reversely associated with HoxB3 expression. Stable overexpression of miR-7 and miR-218 was accompanied by reactivation of tumor suppressor genes including RASSF1A and Claudin-6 by means of epigenetic switches in DNA methylation and histone modification, giving rise to inhibition of the cell cycle and clone formation of breast cancer cells. The current study provides a novel link between overexpression of collinear Hox genes and multiple microRNAs in human breast malignancy.

  1. MICHIGAN SWEEPS NEIGHBORHOODS WITH ENERGY UPGRADES | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... In addition, the Green Fund provides loans to Detroit commercial building owners with loan ... Through the program, contractors learned how to improve their skills in marketing, ...

  2. Loss of expression of miR-335 is implicated in hepatic stellate cell migration and activation

    SciTech Connect (OSTI)

    Chen, Chao; Wu, Chao-Qun; Zhang, Zong-Qi; Yao, Ding-Kang; Zhu, Liang

    2011-07-15

    Activation and migration of resident stellate cells (HSCs) within the hepatic space of Disse play an important role in hepatic fibrosis, which accounts for the increased numbers of activated HSCs in areas of inflammation during hepatic fibrosis. Currently, microRNAs have been found to play essential roles in HSC differentiation, proliferation, apoptosis, fat accumulation and collagen production. However, little is known about microRNA mediated HSC activation and migration. In this study, the miRNA expression profiles of quiescent HSCs, partially activated HSCs and fully activated HSCs were compared in pairs. Gene ontology (GO) and GO-Map network analysis indicated that the activation of HSCs was regulated by microRNAs. Among them miR-335 was confirmed to be significantly reduced during HSC activation by qRT-PCR, and restoring expression of miR-335 inhibited HSC migration and reduced {alpha}-SMA and collagen type I. Previous study revealed that tenascin-C (TNC), an extracellular matrix glycoprotein involved in cell migration, might be a target of miR-335. Therefore, we further studied the TNC expression in miR-335 over-expressed HSCs. Our data showed that exogenous TNC could enhance HSC migration in vitro and miR-335 restoration resulted in a significant inhibition of TNC expression. These results demonstrated that miR-335 restoration inhibited HSC migration, at least in part, via downregulating the TNC expression.

  3. Market values summary/March market review/current market data

    SciTech Connect (OSTI)

    1994-04-01

    This article is the March 1993 uranium market summary. In the natural uranium and concentrates market, there were eight transactions. Both the restricted and unrestricted values were unchanged at $9.45 and $7.00 per pound of U3O8 respectively. In the UF6 market, there were three deals. Both restricted and unrestricted values were also unchanged at $30.00 and $24.50 per kgU as UF6 respectively. The restricted transaction value dropped slightly to $9.45, and the unrestricted value dropped to $7.05. In the enrichment services market, there were six deals reported, with the restricted SWU value rising to $87.00 and the unrestricted SWU value dropping to $67.00. Active uranium demand decreased considerably, while active supply increased.

  4. Energy Information Administration/Petroleum Marketing Annual

    U.S. Energy Information Administration (EIA) Indexed Site

    . . . . . . . . . . . . . . . . - 49 392 Energy Information AdministrationPetroleum Marketing Annual 1998 Kerosene refiners . . . . . . . . . . . . . . . . . . . . . . . . . . ....

  5. Energy Information Administration/Petroleum Marketing Annual

    U.S. Energy Information Administration (EIA) Indexed Site

    . . . . . . . . . . . . . . . . - 49 392 Energy Information AdministrationPetroleum Marketing Annual 1999 Kerosene refiners . . . . . . . . . . . . . . . . . . . . . . . . . . ....

  6. Melamine Formaldehyde Market | OpenEI Community

    Open Energy Info (EERE)

    Melamine Formaldehyde Market Home There are currently no posts in this category. Syndicate content...

  7. March market review. [Spot market prices for uranium (1993)

    SciTech Connect (OSTI)

    Not Available

    1993-04-01

    The spot market price for uranium in unrestricted markets weakened further during March, and at month end, the NUEXCO Exchange Value had fallen $0.15, to $7.45 per pound U3O8. The Restricted American Market Penalty (RAMP) for concentrates increased $0.15, to $2.55 per pound U3O8. Ample UF6 supplies and limited demand led to a $0.50 decrease in the UF6 Value, to $25.00 per kgU as UF6, while the RAMP for UF6 increased $0.75, to $5.25 per kgU. Nine near-term uranium transactions were reported, totalling almost 3.3 million pounds equivalent U3O8. This is the largest monthly spot market volume since October 1992, and is double the volume reported in January and February. The March 31 Conversion Value was $4.25 per kgU as UF6. Beginning with the March 31 Value, NUEXCO now reports its Conversion Value in US dollars per kilogram of uranium (US$/kgU), reflecting current industry practice. The March loan market was inactive with no transactions reported. The Loan Rate remained unchanged at 3.0 percent per annum. Low demand and increased competition among sellers led to a one-dollar decrease in the SWU Value, to $65 per SWU, and the RAMP for SWU declined one dollar, to $9 per SWU.

  8. PSMB4 promotes multiple myeloma cell growth by activating NF-κB-miR-21 signaling

    SciTech Connect (OSTI)

    Zheng, Peihao; Guo, Honggang; Li, Guangchao; Han, Siqi; Luo, Fei; Liu, Yi

    2015-03-06

    Proteasomal subunit PSMB4, was recently identified as potential cancer driver genes in several tumors. However, the regulatory mechanism of PSMB4 on carcinogenesis process remains unclear. In this study, we investigated the expression and roles of PSMB4 in multiple myeloma (MM). We found a significant up-regulation of PSMB4 in MM plasma and cell lines. Ectopic overexpression of PSMB4 promoted cell growth and colony forming ability of MM cells, whereas inhibition of PSMB4 led to a decrease of such events. Furthermore, our results demonstrated the up-regulation of miR-21 and a positive correlation between the levels of miR-21 and PSMB4 in MM. Re-expression of miR-21 markedly rescued PSMB4 knockdown-mediated suppression of cell proliferation and clone-formation. Additionally, while enforced expression of PSMB4 profoundly increased NF-κB activity and the level of miR-21, PSMB4 knockdown or NF-κB inhibition suppressed miR-21 expression in MM cells. Taken together, our results demonstrated that PSMB4 regulated MM cell growth in part by activating NF-κB-miR-21 signaling, which may represent promising targets for novel specific therapies. - Highlights: • First reported upregulation of PSMB4 in MM plasma and cell lines. • PSMB4 promoted MM cell growth and colony forming ability. • Further found miR-21 was up-regulated by PSMB4 in MM plasma and cell lines. • PSMB4-induced miR-21 expression was modulated by NF-κB. • PSMB4-NF-κB-miR-21 axis may be potential therapeutic targets of MM.

  9. Hydropower Market Report | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Hydropower Market Report Hydropower Market Report Hydropower Market Report Top 10 Things You Didn't Know about Hydropower Test your energy knowledge by checking out these surprising facts about hydropower. Get Pumped about Pumped Storage Hydropower Market Report Often described as "giant batteries," pumped storage hydropower (PSH) plants account for the bulk of utility-scale electrical energy storage in the United States and worldwide. Hydropower Still in the Mix Hydropower Market

  10. Financing Program Market Segments | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Market Segments Financing Program Market Segments Financing programs are not one-size-fits-all-different financial products will work better for different market segments. Markets to consider include: Public Sector Residential Commercial and Industrial Select a financing structure in the table for more information. Financing Structures Market Segment Public Sector Residential Commercial Small Business Bonds X X X Clean Renewable Energy Bonds X Energy Efficient Mortgages X Energy Savings

  11. Views on world markets - Canada

    SciTech Connect (OSTI)

    Passmore, J.

    1996-12-31

    If {open_quotes}market{close_quotes} is defined by hardware in the ground (as it should be), then the Canadian wind power market has been virtually non-existent (only 23 MW to date). The potential on the other hand is enormous (6400 MW likely to be developed). This potential has not been pursued because of unregulated electric utility monopolies, lack of political knowledge and interest, and punitive tax treatment for renewables. Recent initiatives including utility restructuring, federal plans for green power procurement, and proposed tax measures suggest that situation has potential for change. Interested parties should start familiarizing themselves with the Canadian players / market now, in order to be ready to move when the time comes (likely in the next three years). 3 tabs.

  12. Petroleum marketing monthly, September 1994

    SciTech Connect (OSTI)

    Not Available

    1994-09-01

    The Petroleum Marketing Monthly (PMM) provides information and statistical data on a variety of crude oils and refined petroleum products. The publication presents statistics on crude oil costs and refined petroleum product sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the f.o.b. and landed cost of imported crude oil, and the refiners` acquisition cost of crude oil. Refined petroleum product sales data include motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane. The Petroleum Marketing Division, Office of Oil and Gas, Energy Information Administration ensures the accuracy, quality, and confidentiality of the published data in the Petroleum Marketing Monthly.

  13. Petroleum marketing monthly, August 1994

    SciTech Connect (OSTI)

    Not Available

    1994-08-15

    The Petroleum Marketing Monthly (PMM) provides information and statistical data on a variety of crude oils and refined petroleum products. The publication presents statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the f.o.b. and landed cost of imported crude oil, and the refiners` acquisition cost of crude oil. Refined petroleum product Sales data include motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane. The Petroleum Marketing Division, Office of Oil and Gas, Energy Information Administration ensures the accuracy, quality, and confidentiality of the published data in the Petroleum Marketing Monthly.

  14. Aryl hydrocarbon receptor-dependent regulation of miR-196a expression controls lung fibroblast apoptosis but not proliferation

    SciTech Connect (OSTI)

    Hecht, Emelia; Zago, Michela; Sarill, Miles; Rico de Souza, Angela; Gomez, Alvin; Matthews, Jason; Hamid, Qutayba; Eidelman, David H.; Baglole, Carolyn J.

    2014-11-01

    The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor implicated in the regulation of apoptosis and proliferation. Although activation of the AhR by xenobiotics such as dioxin inhibits the cell cycle and control apoptosis, paradoxically, AhR expression also promotes cell proliferation and survival independent of exogenous ligands. The microRNA (miRNA) miR-196a has also emerged as a regulator of proliferation and apoptosis but a relationship between the AhR and miR-196a is not known. Therefore, we hypothesized that AhR-dependent regulation of endogenous miR-196a expression would promote cell survival and proliferation. Utilizing lung fibroblasts from AhR deficient (AhR{sup −/−}) and wild-type (AhR{sup +/+}) mice, we show that there is ligand-independent regulation of miRNA, including low miR-196a in AhR{sup −/−} cells. Validation by qRT-PCR revealed a significant decrease in basal expression of miR-196a in AhR{sup −/−} compared to AhR{sup +/+} cells. Exposure to AhR agonists benzo[a]pyrene (B[a]P) and FICZ as well as AhR antagonist CH-223191 decreased miR-196a expression in AhR{sup +/+} fibroblasts concomitant with decreased AhR protein levels. There was increased proliferation only in AhR{sup +/+} lung fibroblasts in response to serum, corresponding to a decrease in p27{sup KIP1} protein, a cyclin-dependent kinase inhibitor. Increasing the cellular levels of miR-196a had no effect on proliferation or expression of p27{sup KIP1} in AhR{sup −/−} fibroblasts but attenuated cigarette smoke-induced apoptosis. This study provides the first evidence that AhR expression is essential for the physiological regulation of cellular miRNA levels- including miR-196a. Future experiments designed to elucidate the functional relationship between the AhR and miR-196a may delineate additional novel ligand-independent roles for the AhR. - Highlights: • The AhR controls proliferation and apoptosis in lung cells. • The AhR regulates the

  15. RLIP76-dependent suppression of PI3K/AKT/Bcl-2 pathway by miR...

    Office of Scientific and Technical Information (OSTI)

    in prostate cancer Citation Details In-Document Search Title: RLIP76-dependent suppression of PI3KAKTBcl-2 pathway by miR-101 induces apoptosis in prostate cancer MicroRNA-101 ...

  16. NERSC-8 Vendor Market Survey

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NERSC-8 Project Lead NERSC-8 Market Survey --- 1 --- November 15, 2012 * Seek v endor i nput t o o p6mize 6 ming, r equirements and business prac6ces * Opportunity f or v endors t o p rovide i nput p rior t o formal p rocurement p rocess We are starting our next procurement, NERSC-8, with a round of market surveys Vendor B riefing --- 2 --- NERSC's mission is to enable science NERSC Mission: To accelerate the pace of scientific discovery by providing high-performance computing, data systems and

  17. 2014 Distributed Wind Market Report

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Wind Capacity Nearing 1 GW Distributed wind cumulative capacity has reached a total of 906 MW from nearly 74,000 wind turbines. In 2014, 23 states added 63.6 MW of new distributed wind capacity, represent- ing nearly 1,700 units and $170 million in investment. 2014 a Mixed Year for Distributed Wind The market for distributed wind systems using large-scale turbines (greater than 1 MW) showed signs of a recovery after low capacity additions in 2013. The markets for distributed wind systems using

  18. May market review. [Spot market prices for uranium (1993)

    SciTech Connect (OSTI)

    Not Available

    1993-06-01

    Seven uranium transactions totalling nearly three million pounds equivalent U3O8 were reported during May, but only two, totalling less than 200 thousand pounds equivalent U3O8, involved concentrates. As no discretionary buying occurred during the month, and as near-term supply and demand were in relative balance, prices were steady, while both buyers and sellers appeared to be awaiting some new market development to signal the direction of future spot-market prices. The May 31, 1993, Exchange Value and the Restricted American market Penalty (RAMP) for concentrates were both unchanged at $7.10, and $2.95 per pound U3O8, respectively. NUEXCO's judgement was that transactions for significant quantities of uranium concentrates that were both deliverable in and intended for consumption in the USA could have been concluded on May 31 at $10.05 per pound U3O8. Two near-term concentrate transactions were reported in which one US utility purchased less than 200 thousand pounds equivalent U3O8 from two separate sellers. These sales occurred at price levels at or near the May 31 Exchange Value plus RAMP. No long-term uranium transactions were reported during May. Consequently, the UF6 Value decreased $0.20 to $24.30 per kgU as UF6, reflecting some weakening of the UF6 market outside the USA.

  19. Global environmental markets: Equity and efficiency

    SciTech Connect (OSTI)

    Chichilnisky, G.

    1997-12-31

    Global markets trading rights to emit greenhouse gases are now actively considered by the United Nations. This leads to a new phenomenon: environmental markets in a global scale. Is this new, or are these markets simply a global manifestation of a trend towards market solutions? This paper will show that there is a fundamental difference between global environmental markets and standard stock exchanges. Because the atmosphere of the planet is one and the same for all, these markets trade {open_quotes}public goods{close_quotes} which are, however, privately produced. These are different from all the goods that are traded in markets today. Efficiency in these markets dictates different rules, involving a more equitable allocation of property rights on environmental use, and this requires new institutional arrangements. There is a need for a new institution, an International Bank for Environmental Settlements (IBES), which can lead to organized trading and ensures market integrity and efficiency.

  20. Material Activation Benchmark Experiments at the NuMI Hadron Absorber Hall in Fermilab

    SciTech Connect (OSTI)

    Matsumura, H.; Matsuda, N.; Kasugai, Y.; Toyoda, A.; Yashima, H.; Sekimoto, S.; Iwase, H.; Oishi, K.; Sakamoto, Y.; Nakashima, H.; Leveling, A.; Boehnlein, D.; Lauten, G.; Mokhov, N.; Vaziri, K.

    2014-06-15

    In our previous study, double and mirror symmetric activation peaks found for Al and Au arranged spatially on the back of the Hadron absorber of the NuMI beamline in Fermilab were considerably higher than those expected purely from muon-induced reactions. From material activation bench-mark experiments, we conclude that this activation is due to hadrons with energy greater than 3 GeV that had passed downstream through small gaps in the hadron absorber.

  1. Port Huron, MI Natural Gas Pipeline Imports From Canada (Million Cubic

    U.S. Energy Information Administration (EIA) Indexed Site

    Feet) Million Cubic Feet) Port Huron, MI Natural Gas Pipeline Imports From Canada (Million Cubic Feet) Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2016 262 278 16 - = No Data Reported; -- = Not Applicable; NA = Not Available; W = Withheld to avoid disclosure of individual company data. Release Date: 08/31/2016 Next Release Date: 09/30/2016 Referring Pages: U.S.

  2. miR-21 modulates tumor outgrowth induced by human adipose tissue-derived mesenchymal stem cells in vivo

    SciTech Connect (OSTI)

    Shin, Keun Koo; Lee, Ae Lim; Kim, Jee Young; Medical Research Center for Ischemic Tissue Engineering, Pusan National University, Yangsan, Gyeongnam 626-870; BK21 Medical Science Education Center, School of Medicine, Pusan National University, Yangsan, Gyeongnam 626-870 ; Lee, Sun Young; Medical Research Center for Ischemic Tissue Engineering, Pusan National University, Yangsan, Gyeongnam 626-870 ; Bae, Yong Chan; Jung, Jin Sup

    2012-06-15

    Highlights: Black-Right-Pointing-Pointer miR-21 modulates hADSC-induced increase of tumor growth. Black-Right-Pointing-Pointer The action is mostly mediated by the modulation of TGF-{beta} signaling. Black-Right-Pointing-Pointer Inhibition of miR-21 enhances the blood flow recovery in hindlimb ischemia. -- Abstract: Mesenchymal stem cells (MSCs) have generated a great deal of interest in clinical situations, due principally to their potential use in regenerative medicine and tissue engineering applications. However, the therapeutic application of MSCs remains limited, unless the favorable effects of MSCs on tumor growth in vivo, and the long-term safety of the clinical applications of MSCs, can be more thoroughly understood. In this study, we determined whether microRNAs can modulate MSC-induced tumor outgrowth in BALB/c nude mice. Overexpression of miR-21 in human adipose-derived stem cells (hADSCs) inhibited hADSC-induced tumor growth, and inhibition of miR-21 increased it. Downregulation of transforming growth factor beta receptor II (TGFBR2), but not of signal transducer and activator of transcription 3, in hADSCs showed effects similar to those of miR-21 overexpression. Downregulation of TGFBR2 and overexpression of miR21 decreased tumor vascularity. Inhibition of miR-21 and the addition of TGF-{beta} increased the levels of vascular endothelial growth factor and interleukin-6 in hADSCs. Transplantation of miR-21 inhibitor-transfected hADSCs increased blood flow recovery in a hind limb ischemia model of nude mice, compared with transplantation of control oligo-transfected cells. These findings indicate that MSCs might favor tumor growth in vivo. Thus, it is necessary to study the long-term safety of this technique before MSCs can be used as therapeutic tools in regenerative medicine and tissue engineering.

  3. Targeting miR-21 enhances the sensitivity of human colon cancer HT-29 cells to chemoradiotherapy in vitro

    SciTech Connect (OSTI)

    Deng, Jun; Lei, Wan; Fu, Jian-Chun; Zhang, Ling; Li, Jun-He; Xiong, Jian-Ping

    2014-01-17

    Highlight: MiR-21 plays a significant role in 5-FU resistance. This role might be attributed to targeting of hMSH2 as well as TP and DPD via miR-21 targeted hMSH2. Indirectly targeted TP and DPD to influence 5-FU chemotherapy sensitivity. -- Abstract: 5-Fluorouracil (5-FU) is a classic chemotherapeutic drug that has been widely used for colorectal cancer treatment, but colorectal cancer cells are often resistant to primary or acquired 5-FU therapy. Several studies have shown that miR-21 is significantly elevated in colorectal cancer. This suggests that this miRNA might play a role in this resistance. In this study, we investigated this possibility and the possible mechanism underlying this role. We showed that forced expression of miR-21 significantly inhibited apoptosis, enhanced cell proliferation, invasion, and colony formation ability, promoted G1/S cell cycle transition and increased the resistance of tumor cells to 5-FU and X radiation in HT-29 colon cancer cells. Furthermore, knockdown of miR-21 reversed these effects on HT-29 cells and increased the sensitivity of HT-29/5-FU to 5-FU chemotherapy. Finally, we showed that miR-21 targeted the human mutS homolog2 (hMSH2), and indirectly regulated the expression of thymidine phosphorylase (TP) and dihydropyrimidine dehydrogenase (DPD). These results demonstrate that miR-21 may play an important role in the 5-FU resistance of colon cancer cells.

  4. Development of Optimal Catalyst Designs and Operating Strategies...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Poster presented at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010. PDF icon p-05harold.pdf More Documents ...

  5. Optical Measurement Methods used in Calibration and Validation...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Poster presented at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010. PDF icon p-07klyza.pdf More Documents ...

  6. Stoney Corners II (REpower) | Open Energy Information

    Open Energy Info (EERE)

    Developer Heritage Sustainable Energy Energy Purchaser Traverse City Light & PowerDetroit Edison Location McBain MI Coordinates 44.209, -85.275 Show Map Loading map......

  7. Integrated Nozzle Flow, Spray, Combustion, & Emission Modeling...

    Broader source: Energy.gov (indexed) [DOE]

    Poster presented at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010. p-13som.pdf (285.53 KB) More Documents ...

  8. Reductant Chemistry during LNT Regeneration for a Lean Gasoline...

    Broader source: Energy.gov (indexed) [DOE]

    Poster presented at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010. p-09parks.pdf (507.29 KB) More ...

  9. Actively controlled vibration welding system and method (Patent...

    Office of Scientific and Technical Information (OSTI)

    OSTI Identifier: 1083924 Assignee: GM Global Technology Operations LLC (Detroit, MI) DOEEE Patent Number(s): 8,408,445 Application Number: 13409,494 Contract Number: EE0002217 ...

  10. Shape memory alloy heat engines and energy harvesting systems...

    Office of Scientific and Technical Information (OSTI)

    Assignee: GM Global Technology Operations LLC (Detroit, MI); Dynalloy, Inc. (Tustin, CA) ARPA-E Patent Number(s): 8,607,562 Application Number: 13340,955 Contract Number: ...

  11. Liquid Propane Injection Applications | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Presentation given at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010. deer10_arnold.pdf (2.27

  12. EA-1690: A123 Systems, Inc., Automotive-Class Lithium-Ion Battery...

    Energy Savers [EERE]

    0: A123 Systems, Inc., Automotive-Class Lithium-Ion Battery Production Facilities near Detroit, MI EA-1690: A123 Systems, Inc., Automotive-Class Lithium-Ion Battery Production ...

  13. Analyses Guided Optimization of Wide Range and High Efficiency...

    Broader source: Energy.gov (indexed) [DOE]

    Presentation given at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010. deer10sun.pdf (999.91 KB) More ...

  14. An Engine System Approach to Exhaust Waste Heat Recovery | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Presentation given at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010. deer10_kruiswyk.pdf (1.43

  15. Improving Diesel Engine Sweet-spot Efficiency and Adapting it...

    Broader source: Energy.gov (indexed) [DOE]

    Poster presented at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010. p-18yan.pdf (213.42 KB) More Documents ...

  16. The Impact of Using Derived Fuel Consumption Maps to Predict...

    Broader source: Energy.gov (indexed) [DOE]

    Poster presented at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010. p-09nuszkowski.pdf (76.33 KB) More ...

  17. Measurement of Pi-K Ratios from the NuMI Target

    SciTech Connect (OSTI)

    Seun, Sin Man; /Harvard U.

    2007-07-01

    Interactions of protons (p) with the NuMI (Neutrinos at the Main Injector) target are used to create the neutrino beam for the MINOS (Main Injector Neutrino Oscillation Search) Experiment. Using the MIPP (Main Injector Particle Production) experimental apparatus, the production of charged pions and kaons in p+NuMI interactions is studied. The data come from a sample of 2 x 10{sup 6} events obtained by MIPP using the 120 GeV/c proton beam from the Main Injector at Fermi National Accelerator Laboratory in Illinois, USA. Pions and kaons are identified by measurement in a Ring Imaging Cherenkov detector. Presented are measurements of {pi}{sup -}/{pi}{sup +}, K{sup -}/K{sup +}, {pi}{sup +}/K{sup +} and {pi}{sup -}/K{sup -} production ratios in the momentum range p{sub T} < 2 GeV/c transversely and 20 GeV/c < p{sub z} < 90 GeV/c longitudinally. Also provided are detailed comparisons of the MIPP NuMI data with the MIPP Thin Carbon data, the MIPP Monte Carlo simulation and the current MINOS models in the relevant momentum ranges.

  18. Market values summary/October market review/current market data

    SciTech Connect (OSTI)

    1994-11-01

    This article is the October uranium market summary. During this period, volume increased to 2.2 Mlb U3O8 on the spot concentrates market. The unrestricted and restricted exchange values remained steady at $7.00 and $9.05 per pound U3O8 respectively. There were two UF6 deals during this period, and with supply more than adequate to meet the demand, the restricted UF6 price remained unchanged at $29.00 per kgU as UF6. The unrestricted value increased slightly to $24.50. The conversion value was unchanged, and the enrichment services market/prices weakened. Both active supply and demand decreased during this period.

  19. Market values summary/March market review/current market data

    SciTech Connect (OSTI)

    1995-04-01

    This article is the March 1995 uranium market summary. There were 14 near-term deals is natural uranium market for a total of 5.2 Mlb. The restricted exchange value moved upward to $11.75 per pound U3O8, and the unrestricted value rose to $7.35. The UF6 market was quite active, with 8 deals and with restricted and unrestricted prices for UF6 both up ($34.75 and $22.50 per kgU as UF6 respectively). The restricted and unrestricted transaction values also rose to $10.05 and $7.25 respectively. Enrichment services followed the overall trend, with increases to $92 and $78 per SWU. Active uranium supply dropped, as did active demand.

  20. miR-502 inhibits cell proliferation and tumor growth in hepatocellular carcinoma through suppressing phosphoinositide 3-kinase catalytic subunit gamma

    SciTech Connect (OSTI)

    Chen, Suling; Li, Fang; Chai, Haiyun; Tao, Xin; Wang, Haili; Ji, Aifang

    2015-08-21

    MicroRNAs (miRNAs) play a key role in carcinogenesis and tumor progression in hepatocellular carcinoma (HCC). In the present study, we demonstrated that miR-502 significantly inhibits HCC cell proliferation in vitro and tumor growth in vivo. G1/S cell cycle arrest and apoptosis of HCC cells were induced by miR-502. Phosphoinositide 3-kinase catalytic subunit gamma (PIK3CG) was identified as a direct downstream target of miR-502 in HCC cells. Notably, overexpression of PIK3CG reversed the inhibitory effects of miR-502 in HCC cells. Our findings suggest that miR-502 functions as a tumor suppressor in HCC via inhibition of PI3KCG, supporting its utility as a promising therapeutic gene target for this tumor type. - Highlights: • miR-502 suppresses HCC cell proliferation in vitro and tumorigenicity in vivo. • miR-502 regulates cell cycle and apoptosis in HCC cells. • PIK3CG is a direct target of miR-502. • miR-502 and PIK3CG expression patterns are inversely correlated in HCC tissues.

  1. 2010 Wind Technologies Market Report

    SciTech Connect (OSTI)

    Wiser, Ryan; Bolinger, Mark

    2011-06-01

    This report provides a comprehensive overview of trends in the U.S. wind power market in 2010. The report analyzes trends in wind power capacity, industry, manufacturing, turbines, installed project costs, project performance, and wind power prices. It also describes trends among wind power developers, project owners, and power purchasers, and discusses financing issues.

  2. Regions in Energy Market Models

    SciTech Connect (OSTI)

    2009-01-18

    This report explores the different options for spatial resolution of an energy market model and the advantages and disadvantages of models with fine spatial resolution. It examines different options for capturing spatial variations, considers the tradeoffs between them, and presents a few examples from one particular model that has been run at different levels of spatial resolution.

  3. Regions in Energy Market Models

    SciTech Connect (OSTI)

    Short, W.

    2007-02-01

    This report explores the different options for spatial resolution of an energy market model--and the advantages and disadvantages of models with fine spatial resolution. It examines different options for capturing spatial variations, considers the tradeoffs between them, and presents a few examples from one particular model that has been run at different levels of spatial resolution.

  4. 2014 Vehicle Technologies Market Report

    SciTech Connect (OSTI)

    Davis, Stacy Cagle; Diegel, Susan W; Boundy, Robert Gary; Moore, Sheila A

    2015-03-01

    This is the sixth edition of this report, which details the major trends in U.S. light-duty vehicle and medium/heavy truck markets as well as the underlying trends that caused them. This report is supported by the U.S. Department of Energy s (DOE) Vehicle Technologies Office (VTO), and, in accord with its mission, pays special attention to the progress of high-efficiency and alternative-fuel technologies. After opening with a discussion of energy and economics, this report features a section each on the light-duty vehicle and heavy/medium truck markets, and concluding with a section each on technology and policy. The first section on Energy and Economics discusses the role of transportation energy and vehicle markets on a national (and even international) scale. The following section examines Light-Duty Vehicle use, markets, manufacture, and supply chains. The discussion of Medium and Heavy Trucks offers information on truck sales and technologies specific to heavy trucks. The Technology section offers information on alternative fuel vehicles and infrastructure, and the Policy section concludes with information on recent, current, and near-future Federal policies like the Corporate Average Fuel Economy standards. In total, the information contained in this report is intended to communicate a fairly complete understanding of U.S. highway transportation energy through a series of easily digestible tables and figures.

  5. 2015 Uranium Marketing Annual Report

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    7 2015 Uranium Marketing Annual Report Release Date: May 24, 2016 Next Release Date: May ... Foreign purchases 19,318 20,196 23,233 24,199 27,233 Weighted-average price 48.80 46.80 ...

  6. 2015 Uranium Marketing Annual Report

    Gasoline and Diesel Fuel Update (EIA)

    9 2015 Uranium Marketing Annual Report Release Date: May 24, 2016 Next Release Date: May ... Foreign sales 4,387 4,798 4,148 4,210 4,258 Weighted-average price 53.08 47.53 43.10 32.91 ...

  7. Coal Market Module - NEMS Documentation

    Reports and Publications (EIA)

    2014-01-01

    Documents the objectives and the conceptual and methodological approach used in the development of the National Energy Modeling System's (NEMS) Coal Market Module (CMM) used to develop the Annual Energy Outlook 2014 (AEO2014). This report catalogues and describes the assumptions, methodology, estimation techniques, and source code of CMM's two submodules. These are the Coal Production Submodule (CPS) and the Coal Distribution Submodule (CDS).

  8. 2014 Distributed Wind Market Report Fact Sheet | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    4 Distributed Wind Market Report Fact Sheet 2014 Distributed Wind Market Report Fact Sheet 2014-Distributed-Wind-Market-Report-Fact-Sheet_05122015_Page_1.jpg 2014 Distributed Wind Market Report Fact Sheet (12.98 MB) More Documents & Publications 2015 Distributed Wind Market Report Fact Sheet 2014 Distributed Wind Market Report Fact Sheet: 2013 Distributed Wind Market Report

  9. 2012 Wind Technologies Market Report | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    2 Wind Technologies Market Report 2012 Wind Technologies Market Report The 2012 Wind Technologies Market Report is a comprehensive analyses of the U.S. distributed wind energy market ever published, this report provides a detailed overview of developments and trends in the U.S. wind power market, focusing on 2012. 2012 Wind Technologies Market Report (3.4 MB) More Documents & Publications 2012 Wind Technologies Market Report 2013 Wind Technologies Market Report 2014 Wind Technologies Market

  10. United States Industrial Electric Motor Systems Market Opportunities...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Electric Motor Systems Market Opportunities Assessment United States Industrial Electric Motor Systems Market Opportunities Assessment The objectives of the Market Assessment were ...

  11. Solar Hot Water Market Development in Knoxville, TN

    Broader source: Energy.gov [DOE]

    Assessment of local solar hot water markets, market variables, market barriers, and suggested strategies to increase solar hot water deployment in the city and county.

  12. Bloomberg New Energy Finance Carbon Markets formerly New Energy...

    Open Energy Info (EERE)

    Bloomberg New Energy Finance Carbon Markets formerly New Energy Finance Carbon Markets Group Jump to: navigation, search Name: Bloomberg New Energy Finance Carbon Markets (formerly...

  13. EA-375 Rainbow Energy Marketing Corporation | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Rainbow Energy Marketing Corporation EA-375 Rainbow Energy Marketing Corporation Order authorizing Rainbow Energy Marketing Corporation to export electric energy to Mexico EA-375 ...

  14. EA-291 Dominion Energy Marketing, Inc. | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Dominion Energy Marketing, Inc. EA-291 Dominion Energy Marketing, Inc. Order authorizing Dominion Energy Marketing, Inc. to export electric energy to Canada EA-291 Dominion Energy ...

  15. EA-337 Synergy Power Marketing, Inc. | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    7 Synergy Power Marketing, Inc. EA-337 Synergy Power Marketing, Inc. Order authorizing Synergy Power Marketing, Inc to export electric energy to Canada EA-337 Synergy Power ...

  16. EA-178-B Edison Mission Marketing & Trading, Inc | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    -B Edison Mission Marketing & Trading, Inc EA-178-B Edison Mission Marketing & Trading, Inc Order authorizing Edison Mission Marketing & Trading, Inc to export electric energy to ...

  17. EA-291-A Dominion Energy Marketing, Inc. | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    -A Dominion Energy Marketing, Inc. EA-291-A Dominion Energy Marketing, Inc. Order authorizing Dominion Energy Marketing, Inc. to export electric energy to Canada EA-291-A Dominion ...

  18. EA-258-B Brookfield Energy Marketing Inc | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    B Brookfield Energy Marketing Inc EA-258-B Brookfield Energy Marketing Inc Order authorizing Brookfield Energy Marketing Inc to export electric energy to Canada. EA-258-B ...

  19. EA-345-A New Brunswick Energy Marketing Corporation | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    -A New Brunswick Energy Marketing Corporation EA-345-A New Brunswick Energy Marketing Corporation Order authorizing New Brunswick Energy Marketing Corp to export electric energy to ...

  20. EA-368 Brookfield Energy Marketing LP | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Brookfield Energy Marketing LP EA-368 Brookfield Energy Marketing LP Order authorizing Brookfield Energy Marketing LP to export electric energy to Canada EA-368 Brookfield Energy ...

  1. EA-208 Williams Energy Marketing and Trading Company | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    8 Williams Energy Marketing and Trading Company EA-208 Williams Energy Marketing and Trading Company Order authorizing Williams Energy Marketing and Trading Company to export ...

  2. 2014 DOE SOLID-STATE LIGHTING MARKET DEVELOPMENT WORKSHOP | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    DOE SOLID-STATE LIGHTING MARKET DEVELOPMENT WORKSHOP 2014 DOE SOLID-STATE LIGHTING MARKET DEVELOPMENT WORKSHOP PDF icon DOE SSL Market Development Workshop Agenda.pdf More...

  3. Building America Webinar: Building America Technology-to-Market...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Technology-to-Market Roadmaps Building America Webinar: Building America Technology-to-Market Roadmaps This webinar introduced the integrated Building America Technology-to-Market ...

  4. EA-258-C Brookfield Energy Marketing Inc | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    C Brookfield Energy Marketing Inc EA-258-C Brookfield Energy Marketing Inc Order authorizing Brookfield Energy Marketing Inc to export electric energy to Canada. EA-258-C ...

  5. 2010 U.S. Lighting Market Characterization - Excel workbook ...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    0 U.S. Lighting Market Characterization - Excel workbook 2010 U.S. Lighting Market Characterization - Excel workbook Contains all data provided in the Lighting Market ...

  6. Federal Offshore--Texas Natural Gas Marketed Production (Million...

    U.S. Energy Information Administration (EIA) Indexed Site

    Marketed Production (Million Cubic Feet) Federal Offshore--Texas Natural Gas Marketed ... Referring Pages: Natural Gas Marketed Production Federal Offshore Texas Natural Gas Gross ...

  7. Louisiana--State Offshore Natural Gas Marketed Production (Million...

    U.S. Energy Information Administration (EIA) Indexed Site

    Marketed Production (Million Cubic Feet) Louisiana--State Offshore Natural Gas Marketed ... Natural Gas Marketed Production Louisiana State Offshore Natural Gas Gross Withdrawals and ...

  8. Texas--State Offshore Natural Gas Marketed Production (Million...

    U.S. Energy Information Administration (EIA) Indexed Site

    Marketed Production (Million Cubic Feet) Texas--State Offshore Natural Gas Marketed ... Referring Pages: Natural Gas Marketed Production Texas State Offshore Natural Gas Gross ...

  9. LBNL Renewable Energy Market and Policy Analysis | Open Energy...

    Open Energy Info (EERE)

    LBNL Renewable Energy Market and Policy Analysis Jump to: navigation, search Logo: Renewable Energy Market and Policy Analysis at LBNL Name Renewable Energy Market and Policy...

  10. LBNL Renewable Energy Market and Policy Analysis | Open Energy...

    Open Energy Info (EERE)

    LBNL Renewable Energy Market and Policy Analysis (Redirected from Renewable Energy Market and Policy Analysis at LBNL) Jump to: navigation, search Logo: Renewable Energy Market and...

  11. Independence Power Marketing | Open Energy Information

    Open Energy Info (EERE)

    Power Marketing Jump to: navigation, search Name: Independence Power Marketing Place: New York References: EIA Form EIA-861 Final Data File for 2010 - File1a1 EIA Form 861 Data...

  12. Optim Energy Marketing LLC | Open Energy Information

    Open Energy Info (EERE)

    Optim Energy Marketing LLC Jump to: navigation, search Name: Optim Energy Marketing LLC Place: Texas References: EIA Form EIA-861 Final Data File for 2010 - File1a1 EIA Form 861...

  13. Dynegy Power Marketing Inc | Open Energy Information

    Open Energy Info (EERE)

    Dynegy Power Marketing Inc Jump to: navigation, search Name: Dynegy Power Marketing Inc Place: Texas Phone Number: 1.800.633.4704 or 713.507.6400 Website: www.dynegy.com Outage...

  14. Carbon Capital Markets | Open Energy Information

    Open Energy Info (EERE)

    Capital Markets Jump to: navigation, search Name: Carbon Capital Markets Place: London, United Kingdom Zip: W1J 8DY Sector: Carbon Product: London-based fund manager and trader...

  15. 2016 National Symposium on Market Transformation | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    National Symposium on Market Transformation 2016 National Symposium on Market Transformation March 20, 2016 9:00AM EDT to March 22, 2016 5:00PM EDT Hyatt Regency Baltimore ...

  16. Fuel Cell Markets Ltd | Open Energy Information

    Open Energy Info (EERE)

    Cell Markets Ltd Place: Buckinghamshire, United Kingdom Zip: SL0 9AQ Sector: Hydro, Hydrogen Product: Fuel Cell Markets was set up to assist companies in the fuel cell and...

  17. Solar Tracker Market | OpenEI Community

    Open Energy Info (EERE)

    Solar Tracker Market Home Wayne31jan's picture Submitted by Wayne31jan(150) Contributor 22 June, 2015 - 00:57 Amplified Demand for Solar Trackers to Boost Market Growth in Middle...

  18. 2014 Wind Market Report | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    4 Wind Market Report 2014 Wind Market Report Addthis 1 of 8 2 of 8 3 of 8 4 of 8 5 of 8 6 of 8 7 of 8 8 of 8

  19. ,"West Virginia Natural Gas Marketed Production (MMcf)"

    U.S. Energy Information Administration (EIA) Indexed Site

    AM" "Back to Contents","Data 1: West Virginia Natural Gas Marketed Production (MMcf)" "Sourcekey","N9050WV2" "Date","West Virginia Natural Gas Marketed Production (MMcf)" ...

  20. Economics and regulation of petroleum futures markets

    SciTech Connect (OSTI)

    Not Available

    1980-08-01

    Because the futures market in petroleum products is a relatively recent phenomenon, the implications of public policies formulated for that market have not yet been fully explored. To provide the Office of Competition of the Department of Energy (DOE) with sufficient information to assess policy alternatives, Resource Planning Associates, Inc. (RPA) was asked to analyze the development of the futures market in No. 2 oil, assess the potential for futures markets in other petroleum products, and identify policy alternatives available to DOE. To perform this analysis, the criteria for a viable futures market was established first. Then, the experience to date with the 18-month-old futures market in No. 2 oil was examined, and the potential for viable futures markets in No. 6 oil, gasoline, jet fuel, and crude oil was assessed. Finally, how existing DOE regulations and prospective actions might affect petroleum futures market development was investigated.

  1. ,"New Mexico Natural Gas Marketed Production (MMcf)"

    U.S. Energy Information Administration (EIA) Indexed Site

    9:53:47 AM" "Back to Contents","Data 1: New Mexico Natural Gas Marketed Production (MMcf)" "Sourcekey","N9050NM2" "Date","New Mexico Natural Gas Marketed Production (MMcf)" ...

  2. ,"New Mexico Natural Gas Marketed Production (MMcf)"

    U.S. Energy Information Administration (EIA) Indexed Site

    9:53:46 AM" "Back to Contents","Data 1: New Mexico Natural Gas Marketed Production (MMcf)" "Sourcekey","N9050NM2" "Date","New Mexico Natural Gas Marketed Production (MMcf)" ...

  3. ,"North Dakota Natural Gas Marketed Production (MMcf)"

    U.S. Energy Information Administration (EIA) Indexed Site

    9:53:45 AM" "Back to Contents","Data 1: North Dakota Natural Gas Marketed Production (MMcf)" "Sourcekey","N9050ND2" "Date","North Dakota Natural Gas Marketed Production ...

  4. ,"North Dakota Natural Gas Marketed Production (MMcf)"

    U.S. Energy Information Administration (EIA) Indexed Site

    9:53:46 AM" "Back to Contents","Data 1: North Dakota Natural Gas Marketed Production (MMcf)" "Sourcekey","N9050ND2" "Date","North Dakota Natural Gas Marketed Production ...

  5. Hydraulic Fracturing Market | OpenEI Community

    Open Energy Info (EERE)

    Hydraulic Fracturing Market Home Wayne31jan's picture Submitted by Wayne31jan(150) Contributor 30 June, 2015 - 03:49 Shale Gas Application in Hydraulic Fracturing Market is likely...

  6. "2014 Retail Power Marketers Sales- Residential"

    U.S. Energy Information Administration (EIA) Indexed Site

    ... Solutions Corp.","IL","Power Marketer",477853,4492034,227638.8,5.0676108 "Green Mountain Energy Company","IL","Power Marketer",24959,190336,16176.4,8.4988652 "Homefield ...

  7. "2014 Retail Power Marketers Sales- Total"

    U.S. Energy Information Administration (EIA) Indexed Site

    ... "Glacial Energy Holdings","IL","Power Marketer",2426,128194,8721.1,6.8030485 "Green Mountain Energy Company","IL","Power Marketer",24967,198273,16620.1,8.3824323 "Homefield ...

  8. "2014 Retail Power Marketers Sales- Commercial"

    U.S. Energy Information Administration (EIA) Indexed Site

    ... "Glacial Energy Holdings","IL","Power Marketer",2426,128194,8721.1,6.8030485 "Green Mountain Energy Company","IL","Power Marketer",8,7937,443.7,5.5902734 "Homefield ...

  9. Market values summary/May market review/current market data

    SciTech Connect (OSTI)

    1994-06-01

    This article is the May 1994 uranium market survey. In the spot concentrates market, there was only one new deal, and as a result, the restricted exchange value eased to $9.25 per pound U3O8. The unrestricted exchange value remained constant at $7.00. There were two deals in the UF6 spot market, and the restricted UF6 value decreased to $29.40 per kgU as UF6. The unrestricted UF6 value was unchanged. There were two deals in the long-term marketplace. The restricted transaction value declined to $9.40 per pound U3O8, and the unrestricted transaction value remained fixed at $7.05. There were three deals in the enrichment services market, and the restricted SWU value dropped to $87 per SWU, while the unrestricted SWU value remained constant at $67. Active uranium supply decreased this reporting period, while active demand increased. Supply continued to overwhelm demand, however.

  10. MiR-145 is downregulated in human ovarian cancer and modulates cell growth and invasion by targeting p70S6K1 and MUC1

    SciTech Connect (OSTI)

    Wu, Huijuan; Xiao, ZhengHua; Wang, Ke; Liu, Wenxin; Hao, Quan

    2013-11-29

    Highlights: MiR-145 is downregulated in human ovarian cancer. MiR-145 targets p70S6K1 and MUC1. p70S6K1 and MUC1 are involved in miR-145 mediated tumor cell growth and cell invasion, respectively. -- Abstract: MicroRNAs (miRNAs) are a family of small non-coding RNA molecules that regulate gene expression at post-transcriptional levels. Previous studies have shown that miR-145 is downregulated in human ovarian cancer; however, the roles of miR-145 in ovarian cancer growth and invasion have not been fully demonstrated. In the present study, Northern blot and qRT-PCR analysis indicate that miR-145 is downregulated in ovarian cancer tissues and cell lines, as well as in serum samples of ovarian cancer, compared to healthy ovarian tissues, cell lines and serum samples. Functional studies suggest that miR-145 overexpression leads to the inhibition of colony formation, cell proliferation, cell growth viability and invasion, and the induction of cell apoptosis. In accordance with the effect of miR-145 on cell growth, miR-145 suppresses tumor growth in vivo. MiR-145 is found to negatively regulate P70S6K1 and MUC1 protein levels by directly targeting their 3?UTRs. Importantly, the overexpression of p70S6K1 and MUC1 can restore the cell colony formation and invasion abilities that are reduced by miR-145, respectively. MiR-145 expression is increased after 5-aza-CdR treatment, and 5-aza-CdR treatment results in the same phenotype as the effect of miR-145 overexpression. Our study suggests that miR-145 modulates ovarian cancer growth and invasion by suppressing p70S6K1 and MUC1, functioning as a tumor suppressor. Moreover, our data imply that miR-145 has potential as a miRNA-based therapeutic target for ovarian cancer.

  11. April market review. [Spot market prices for uranium (1993)

    SciTech Connect (OSTI)

    Not Available

    1993-05-01

    The spot market price for uranium outside the USA weakened further during April, and at month end, the NUEXCO Exchange Value had fallen $0.35, to $7.10 per pound U3O8. This is the lowest Exchange Value observed in nearly twenty years, comparable to Values recorded during the low price levels of the early 1970s. The Restricted American Market Penalty (RAMP) for concentrates increased $0.40, to $2.95 per pound U3O8. Transactions for significant quantities of uranium concentrates that are both deliverable in and intended for consumption in the USA could have been concluded on April 30 at $10.05 per pound U3O8, up $0.05 from the sum of corresponding March Values. Four near-term concentrates transactions were reported, totalling nearly 1.5 million pounds equivalent U3O8. One long-term sale was reported. The UF6 Value also declined, as increased competition among sellers led to a $0.50 decrease, to $24.50 per kgU as UF6. However, the RAMP for UF6 increased $0.65, to $5.90 per kgU as UF6, reflecting an effective US market level of $30.40 per kgU. Two near term transactions were reported totalling approximately 1.1 million pounds equivalent U3O8. In total, eight uranium transactions totalling 28 million pounds equivalent U3O8 were reported, which is about average for April market activity.

  12. Biofuels Market Opportunities | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Biofuels Market Opportunities Biofuels Market Opportunities Breakout Session 2C-Fostering Technology Adoption II: Expanding the Pathway to Market Biofuels Market Opportunities John Eichberger, Vice President Government Relations, National Association of Convenience Stores eichberger_biomass_2014.pdf (727.47 KB) More Documents & Publications End Use and Fuel Certification Fuels of the Future: Accelerating the Co-Optimization of Fuels and Engines Flexible Fuel Vehicles: Providing a Renewable

  13. Energy Market Analysis | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Market Analysis Energy Market Analysis Energy Market Analysis synthesizes all analysis efforts in the analysis spectrum. Scenario analyses, in the context of market analysis, are used to answer several questions: What are the feasible options for developing a future in which hydrogen plays a role? What are the impacts, costs, and financial risks of the various scenarios for transitioning to the hydrogen future? Which technologies are most likely to be a part of the hydrogen future, and

  14. Value of Flexibility in the Markets

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Value of Flexibility in the Markets * Basic overview of the SPP and MISO markets * Potential benefit to some SPA customers of using markets to schedule energy * Increasing need for ancillary services, and the value of ancillary services in the markets 3 From presentation by ERCOT: Operational Challenges due to High Wind * Higher frequency deviations due to large system excursions * Inadequate transmission for projected wind growth * Constraint management under high and low wind * Difficulty in

  15. Emergence of Natural Gas Market Centers

    Reports and Publications (EIA)

    1996-01-01

    Discusses the value of market centers in today's marketplace, highlighting their importance in capacity and financial transactions.

  16. Southeast European Regional Electricity Market Analysis | Open...

    Open Energy Info (EERE)

    National Laboratory Partner United States Agency for International Development, Montgomery Watson Harza Sector Energy Topics Market analysis, Background analysis Website...

  17. Solar Energy Technologies Program: Market Transformation

    SciTech Connect (OSTI)

    2009-10-26

    Fact sheet summarizing the goals and activities of the DOE Solar Energy Technologies Program efforts within its market transformation subprogram

  18. Residential market transformation: National and regional indicators

    SciTech Connect (OSTI)

    Van Wie McGrory, Laura L.; McNamara, Maureen; Suozzo, Margaret

    2000-06-01

    A variety of programs are underway to address market barriers to the adoption of energy-efficient residential technologies and practices. Most are administered by utilities, states, or regions that rely on the Energy Star as a consistent platform for program marketing and messaging. This paper reviews regional and national market transformation activities for three key residential end-uses -- air conditioning, clothes washing, and lighting -- characterizing current and ongoing programs; reporting on progress; identifying market indicators; and discussing implications.

  19. Shading, Films and Window Attachments Market Report

    Broader source: Energy.gov [DOE]

    Shading, Films and Window Attachments (SFWA) Market Report, March 13, 2016, from the Consortium for Building Energy Innovation.

  20. National Renewable Energy Laboratory Technology Marketing Summaries -

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Energy Innovation Portal National Renewable Energy Laboratory Technology Marketing Summaries Here you'll find marketing summaries for technologies available for licensing from the National Renewable Energy Laboratory (NREL). The summaries provide descriptions of the technologies including their benefits, applications and industries, and development stage. National Renewable Energy Laboratory 129 Technology Marketing Summaries Category Title and Abstract Laboratories Date Solar Photovoltaic