Sample records for lovelace respiratory research

  1. Verification Survey of Rooms 113, 114, and 208 of the Inhalation Toxicology Laboratory, Lovelace Respiratory Research Institute, Albuquerque, NM

    SciTech Connect (OSTI)

    T.J. Vitkus

    2008-06-25T23:59:59.000Z

    The objectives of the verification survey were to confirm that accessible surfaces of the three laboratories meet the DOE’s established criteria for residual contamination. Drain pipes and ductwork were not included within the survey scope.

  2. Inhalation Toxicology Research Institute. Annual report, October 1, 1995--September 30, 1996

    SciTech Connect (OSTI)

    Bice, D.E.; Hahn, F.F.; Henderson, R.F. [eds.] [and others

    1996-12-01T23:59:59.000Z

    The Inhalation Toxicology Research Institute (ITRI) is a Government-owned facility leased and operated by the Lovelace Biomedical and Environmental Research Institute (LBERI) as a private, nonprofit research and testing laboratory. LBERI is an operating subsidiary of the Lovelace Respiratory Research Institute. Through September 30, 1996, ITRI was a Federally Funded Research and Development Center operated by Lovelace for the US Department of Energy (DOE) as a {open_quotes}Single Program Laboratory{close_quotes} within the DOE Office of Health and Environmental Research, Office of Energy Research. Work for DOE continues in the privatized ITRI facility under a Cooperative Agreement. At the time of publication, approximately 70% of the Institute`s research is funded by DOE, and the remainder is funded by a variety of Federal agency, trade association, individual industry, and university customers. The principal mission of ITRI is to conduct basic and applied research to improve our understanding of the nature and magnitude of the human health impacts of inhaling airborne materials in the home, workplace, and general environment. Institute research programs have a strong basic science orientation with emphasis on the nature and behavior of airborne materials, the fundamental biology of the respiratory tract, the fate of inhaled materials and the mechanisms by which they cause disease, and the means by which data produced in the laboratory can be used to estimate risks to human health. Disorders of the respiratory tract continue to be a major health concern, and inhaled toxicants are thought to contribute substantially to respiratory morbidity. As the country`s largest facility dedicated to the study of basic inhalation toxicology, ITRI provides a national resource of specialized facilities, personnel, and educational activities serving the needs of government, academia, and industry.

  3. Van de Louw et al. Respiratory Research 2010, 11:38 http://respiratory-research.com/content/11/1/38

    E-Print Network [OSTI]

    Boyer, Edmond

    Van de Louw et al. Respiratory Research 2010, 11:38 http://respiratory-research.com/content/11 cardiovascular variability and baroreflex gain in mechanically ventilated patients Andry Van de Louw*1,2, Claire nervous system. During spontaneous breathing, the application of positive end- expiratory pressure (PEEP

  4. Relationship Between Composition and Toxicity of Engine Emission...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Emission Samples Relationship Between Composition and Toxicity of Engine Emission Samples 2003 DEER Conference Presentation: Lovelace Respiratory Research Institute...

  5. Respiratory protection at nuclear power plants

    SciTech Connect (OSTI)

    Reinert, B.D.

    1982-01-01T23:59:59.000Z

    Highlights of the respiratory protection research and development program conducted at Los Alamos is reviewed. (ACR)

  6. deprivation respiratory

    E-Print Network [OSTI]

    Yang, Junfeng

    measured oxidation administration mechanism capacity binding intake pregnancy system deficient quality activity nocturnal treatment duration respiratory daytime pattern circadian normal problem function mechanism baseline disturbance apnoea cat delta analysis temperature parameter shift human states

  7. Respiratory Mechanisms of Support

    E-Print Network [OSTI]

    Kay, Mark A.

    Respiratory Mechanisms of Support Nasal Cannula Hi Flow Nasal Cannula CPAP Continuous positive the respiratory system is working to compensate for a metabolic issue so as to normalize the blood pH. HCO3 - 22 uses PIP Mechanical Ventilation: Volume vs. Pressure: Volume Control Pressure Control Cycle Volume Time

  8. acute respiratory illness: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    syndrome. METHODS As shown in Figure 1 related to lower respiratory illness (e.g., cough, shortness of breath, pneumonia on x-ray, oxygen Boyer, Edmond 4 Edinburgh Research...

  9. Multiplex detection of respiratory pathogens

    DOE Patents [OSTI]

    McBride, Mary (Brentwood, CA); Slezak, Thomas (Livermore, CA); Birch, James M. (Albany, CA)

    2012-07-31T23:59:59.000Z

    Described are kits and methods useful for detection of respiratory pathogens (influenza A (including subtyping capability for H1, H3, H5 and H7 subtypes) influenza B, parainfluenza (type 2), respiratory syncytial virus, and adenovirus) in a sample. Genomic sequence information from the respiratory pathogens was analyzed to identify signature sequences, e.g., polynucleotide sequences useful for confirming the presence or absence of a pathogen in a sample. Primer and probe sets were designed and optimized for use in a PCR based, multiplexed Luminex assay to successfully identify the presence or absence of pathogens in a sample.

  10. Respiratory correlated cone beam CT

    SciTech Connect (OSTI)

    Sonke, Jan-Jakob; Zijp, Lambert; Remeijer, Peter; Herk, Marcel van [Department of Radiation Oncology, Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam (Netherlands)

    2005-04-01T23:59:59.000Z

    A cone beam computed tomography (CBCT) scanner integrated with a linear accelerator is a powerful tool for image guided radiotherapy. Respiratory motion, however, induces artifacts in CBCT, while the respiratory correlated procedures, developed to reduce motion artifacts in axial and helical CT are not suitable for such CBCT scanners. We have developed an alternative respiratory correlated procedure for CBCT and evaluated its performance. This respiratory correlated CBCT procedure consists of retrospective sorting in projection space, yielding subsets of projections that each corresponds to a certain breathing phase. Subsequently, these subsets are reconstructed into a four-dimensional (4D) CBCT dataset. The breathing signal, required for respiratory correlation, was directly extracted from the 2D projection data, removing the need for an additional respiratory monitor system. Due to the reduced number of projections per phase, the contrast-to-noise ratio in a 4D scan reduced by a factor 2.6-3.7 compared to a 3D scan based on all projections. Projection data of a spherical phantom moving with a 3 and 5 s period with and without simulated breathing irregularities were acquired and reconstructed into 3D and 4D CBCT datasets. The positional deviations of the phantoms center of gravity between 4D CBCT and fluoroscopy were small: 0.13{+-}0.09 mm for the regular motion and 0.39{+-}0.24 mm for the irregular motion. Motion artifacts, clearly present in the 3D CBCT datasets, were substantially reduced in the 4D datasets, even in the presence of breathing irregularities, such that the shape of the moving structures could be identified more accurately. Moreover, the 4D CBCT dataset provided information on the 3D trajectory of the moving structures, absent in the 3D data. Considerable breathing irregularities, however, substantially reduces the image quality. Data presented for three different lung cancer patients were in line with the results obtained from the phantom study. In conclusion, we have successfully implemented a respiratory correlated CBCT procedure yielding a 4D dataset. With respiratory correlated CBCT on a linear accelerator, the mean position, trajectory, and shape of a moving tumor can be verified just prior to treatment. Such verification reduces respiration induced geometrical uncertainties, enabling safe delivery of 4D radiotherapy such as gated radiotherapy with small margins.

  11. NICS report links VOCs to respiratory problems

    SciTech Connect (OSTI)

    Kirschner, E.

    1992-04-22T23:59:59.000Z

    Children who live near the chemical plants of Kanawha Valley, WV, suffer more acute and chronic respiratory aliments than those farther away, says a Harvard University School of Public Health report. In the $1-million, five-year study commissioned by the National Institute for Chemical Studies (NICS:Charleston, WV) and funded by the Environmental Protection Agency, proximity to chemical plants that emit volatile organic compounds (VOCs) was linked to higher incidence of asthma, acute eye irritation, shortness of breath, and chronic cough. The researchers say they adjusted for most other factors, such as parental smoking and petroleum. {open_quotes}The research hypothesis was whether children in the valley had more symptoms,{close_quotes} says NICS president Paul Hill. {open_quotes}Yes, there is a difference.{close_quotes} The study showed that some ailments were up to 28% more prevalent in children in the valley than in other Kanawha County children.

  12. SU-E-J-48: Development of An Abdominal Compression Device for Respiratory Correlated Radiation Therapy

    SciTech Connect (OSTI)

    Kim, T; Kang, S; Kim, D; Suh, T [Catholic University Medical College, Seoul (Korea, Republic of); Kim, S [Virginia Commonwealth University, Richmond, VA (United States)

    2014-06-01T23:59:59.000Z

    Purpose: The aim of this study is to develop the abdominal compression device which could control pressure level according to the abdominal respiratory motion and evaluate its feasibility. Methods: In this study, we focused on developing the abdominal compression device which could control pressure level at any point of time so the developed device is possible to use a variety of purpose (gating technique or respiratory training system) while maintaining the merit of the existing commercial device. The compression device (air pad form) was designed to be able to compress the front and side of abdomen and the pressure level of the abdomen is controlled by air flow. Pressure level of abdomen (air flow) was determined using correlation data between external abdominal motion and respiratory volume signal measured by spirometer. In order to verify the feasibility of the device, it was necessary to confirm the correlation between the abdominal respiratory motion and respiratory volume signal and cooperation with respiratory training system also checked. Results: In the previous study, we could find that the correlation coefficient ratio between diaphragm and respiratory volume signal measured by spirometer was 0.95. In this study, we confirmed the correlation between the respiratory volume signal and the external abdominal motion measured by belt-transducer (correlation coefficient ratio was 0.92) and used the correlated respiratory volume data as an abdominal pressure level. It was possible to control the pressure level with negligible time delay and respiratory volume data based guiding waveforms could be properly inserted into the respiratory training system. Conclusion: Through this feasibility study, we confirmed the correlation between the respiratory volume signal and the external abdominal motion. Also initial assessment of the device and its compatibility with the respiratory training system were verified. Further study on application in respiratory gated therapy and respiratory training system will be investigated. This work was supported by Radiation Technology R and D program (No. 2013M2A2A7043498)and Basic Atomic Energy Research Institute (BAERI)(No. NRF-2009-0078390) through the National Research Foundation of Korea funded by the Ministry of Science, ICT and Future Planning.

  13. Improved Radiation Dosimetry/Risk Estimates to Facilitate Environmental Management of Plutonium-Contaminated Sites

    SciTech Connect (OSTI)

    Scott, Bobby R.; Tokarskaya, Zoya B.; Zhuntova, Galina V.; Osovets, Sergey V.; Syrchikov, Victor A., Belyaeva, Zinaida D.

    2007-12-14T23:59:59.000Z

    This report summarizes 4 years of research achievements in this Office of Science (BER), U.S. Department of Energy (DOE) project. The research described was conducted by scientists and supporting staff at Lovelace Respiratory Research Institute (LRRI)/Lovelace Biomedical and Environmental Research Institute (LBERI) and the Southern Urals Biophysics Institute (SUBI). All project objectives and goals were achieved. A major focus was on obtaining improved cancer risk estimates for exposure via inhalation to plutonium (Pu) isotopes in the workplace (DOE radiation workers) and environment (public exposures to Pu-contaminated soil). A major finding was that low doses and dose rates of gamma rays can significantly suppress cancer induction by alpha radiation from inhaled Pu isotopes. The suppression relates to stimulation of the body's natural defenses, including immunity against cancer cells and selective apoptosis which removes precancerous and other aberrant cells.

  14. A linear time-varying simulation of the respiratory system

    E-Print Network [OSTI]

    Hernandez, Oscar Renato

    1993-01-01T23:59:59.000Z

    aerosols with constant transfer rates in a linear distribution of compartments representing three physiological regions of the respiratory system. This approach was selected by the Task Group to simplify nonlinear parameters such as macrophage uptake... of the action of physicochemical and biological factors that play a role in converting aerosol particles to a chemical form that is absorbed to the blood. In this research, using the same compartmental distribution as that proposed by the ICRP Task Group, a...

  15. MULTISCALE MODELING OF THE RESPIRATORY TRACT

    E-Print Network [OSTI]

    Maury, Bertrand

    correspond to di®erent mechanical models. The resulting system is described by the NavierŔStokes equation of the respiratory tree into three stages where di®erent models will be exploited and in which the mechanicalMULTISCALE MODELING OF THE RESPIRATORY TRACT LEONARDO BAFFICO Laboratoire de Mathematiques N

  16. acidosis respiratory: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Pulmonary Disease (COPD) as a proxy for respiratory across small urban areas or individuals. Keywords: Respiratory health, Chronic obstructive pulmonary disease, Cities,...

  17. POYNTING JETS FROM ACCRETION DISKS R. V. E. Lovelace,1

    E-Print Network [OSTI]

    for the understanding of the jets from active galactic nuclei, microquasars, and possibly gamma-ray burst sources by the electromagnetic field, which is relevant to extragalactic and microquasar jets and possibly to gamma-ray burst- sion-line jets are seen in young stellar objects (Mundt 1985; Bu¨ehrke, Mundt, & Ray 1988). Recent work

  18. From: Eric Lovelace To: Congestion Study Comments Subject:

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't YourTransport inEnergy0.pdf Flash2010-60.pdf2 DOEScienceNIETCMunsonNewacheck6:21 AM IEric

  19. Elec 331 -Respiratory System SRC: AnatomyWarehouse.com

    E-Print Network [OSTI]

    Pulfrey, David L.

    - Respiratory System 4 Mechanics of Breathing Lung Visceral Pleura (attached to lung) Parietal Pleura (attachedElec 331 - Respiratory System 1 SRC: AnatomyWarehouse.com C-V / Respiratory System Hot Water #12;Elec 331 - Respiratory System 2 Alveoli Pharynx (throat) Larynx (voice box / Adam's Apple) Trachea

  20. Clinical correlates and epidemiology of respiratory viruses 

    E-Print Network [OSTI]

    Gaunt, Eleanor

    2011-07-05T23:59:59.000Z

    The introduction of the polymerase chain reaction (PCR) into the diagnostic setting has provided unprecedented opportunities in the field of respiratory medicine, not only because pathogens need no longer be cultivable ...

  1. Mitochondrial Respiratory Capacity Is a Critical Regulator

    E-Print Network [OSTI]

    respiratory capacity (SRC). SRC is the extra capacity available in cells to produce energy in response. In response to antigen (Ag) and costimulation, CD8+ T cells undergo a developmental program characterized- ating in response to Ag, it is thought that quiescent T cells (e.g., naive and memory T cells), like

  2. Modeling the Dynamics of Fermentation and Respiratory

    E-Print Network [OSTI]

    Sheffield, University of

    , denitrification, and SO4-reduction). The accumulation of acetate as a fermentation product within the plume species, e.g., H2(aq) or acetate, followed by respiration by other groups of organisms where fermentationModeling the Dynamics of Fermentation and Respiratory Processes in a Groundwater Plume of Phenolic

  3. Separating respiratory influences from the tachogram: methods and their sensitivity to the type of respiratory signal

    E-Print Network [OSTI]

    ECG- derived respiratory (EDR) signals. The sensitivity of both separation methods to the type signals. Even when an EDR signal obtained using kernel principal com- ponent analysis is used, OSP yields

  4. REGULAR ARTICLE A Simple Dynamic Model of Respiratory Pump

    E-Print Network [OSTI]

    Fontecave-Jallon, Julie

    ). Mathematical models are used to understand these interactions and the mechanics of respiratory system better) and introduce some dynamic properties of the respiratory system. The passive elements (rib cage and abdomen not take into account the dynamic component of the system, it appears valid for different respiratory

  5. Nitrogen dioxide and respiratory illnesses in infants

    SciTech Connect (OSTI)

    Samet, J.M.; Lambert, W.E.; Skipper, B.J.; Cushing, A.H.; Hunt, W.C.; Young, S.A.; McLaren, L.C.; Schwab, M.; Spengler, J.D. (Univ. of New Mexico Medical Center, Albuquerque (United States))

    1993-11-01T23:59:59.000Z

    Nitrogen dioxide is an oxidant gas that contaminates outdoor air and indoor air in homes with unvented gas appliances. A prospective cohort study was carried out to test the hypothesis that residential exposure to NO2 increases incidence and severity of respiratory illnesses during the first 18 months of life. A cohort of 1,205 healthy infants from homes without smokers was enrolled. The daily occurrence of respiratory symptoms and illnesses was reported by the mothers every 2 wk. Illnesses with wheezing or wet cough were classified as lower respiratory tract. Indoor NO2 concentrations were serially measured with passive samplers place in the subjects' bedrooms. In stratified analyses, illness incidence rates did not consistently increase with exposure to NO2 or stove type. In multivariate analyses that adjusted for potential confounding factors, odds ratios were not significantly elevated for current or lagged NO2 exposures, or stove type. Illness duration, a measure of illness severity, was not associated with NO2 exposure. The findings can be extended to homes with gas stoves in regions of the United States where the outdoor air is not heavily polluted by NO2.

  6. SU-E-J-261: Statistical Analysis and Chaotic Dynamics of Respiratory Signal of Patients in BodyFix

    SciTech Connect (OSTI)

    Michalski, D; Huq, M; Bednarz, G; Lalonde, R; Yang, Y; Heron, D [University of Pittsburgh Medical Center, Pittsburgh, PA (United States)

    2014-06-01T23:59:59.000Z

    Purpose: To quantify respiratory signal of patients in BodyFix undergoing 4DCT scan with and without immobilization cover. Methods: 20 pairs of respiratory tracks recorded with RPM system during 4DCT scan were analyzed. Descriptive statistic was applied to selected parameters of exhale-inhale decomposition. Standardized signals were used with the delay method to build orbits in embedded space. Nonlinear behavior was tested with surrogate data. Sample entropy SE, Lempel-Ziv complexity LZC and the largest Lyapunov exponents LLE were compared. Results: Statistical tests show difference between scans for inspiration time and its variability, which is bigger for scans without cover. The same is for variability of the end of exhalation and inhalation. Other parameters fail to show the difference. For both scans respiratory signals show determinism and nonlinear stationarity. Statistical test on surrogate data reveals their nonlinearity. LLEs show signals chaotic nature and its correlation with breathing period and its embedding delay time. SE, LZC and LLE measure respiratory signal complexity. Nonlinear characteristics do not differ between scans. Conclusion: Contrary to expectation cover applied to patients in BodyFix appears to have limited effect on signal parameters. Analysis based on trajectories of delay vectors shows respiratory system nonlinear character and its sensitive dependence on initial conditions. Reproducibility of respiratory signal can be evaluated with measures of signal complexity and its predictability window. Longer respiratory period is conducive for signal reproducibility as shown by these gauges. Statistical independence of the exhale and inhale times is also supported by the magnitude of LLE. The nonlinear parameters seem more appropriate to gauge respiratory signal complexity since its deterministic chaotic nature. It contrasts with measures based on harmonic analysis that are blind for nonlinear features. Dynamics of breathing, so crucial for 4D-based clinical technologies, can be better controlled if nonlinear-based methodology, which reflects respiration characteristic, is applied. Funding provided by Varian Medical Systems via Investigator Initiated Research Project.

  7. Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Scienceand Requirements Recently ApprovedReliabilityPrincipal Investigators PostdoctoralResearch

  8. The effects of mechanical ventilation on the development of Acute Respiratory Distress Syndrome

    E-Print Network [OSTI]

    Jia, Xiaoming, M. Eng. Massachusetts Institute of Technology

    2007-01-01T23:59:59.000Z

    Acute Respiratory Distress Syndrome (ARDS) is a severe lung illness characterized by inflammation and fluid accumulation in the respiratory system. Historically, ARDS and other forms of respiratory failure have been treated ...

  9. Respiratory and Cardiovascular Adjustments to Exercise in Reptiles

    E-Print Network [OSTI]

    Bennett, Albert F.

    challenges to the respiratory system of reptiles. Incrementing aerobic metabolism above resting levelsRespiratory and Cardiovascular Adjustments to Exercise in Reptiles T.T. GLEESON ' and A.F. BEN NETT all levels of activity (Fig. lb). The mechanism for an- aerobic energy production during exercise

  10. Multiscale modelling of the respiratory tract C. Grandmont

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    to different mechanical models. The resulting system is described by the Navier-Stokes equation coupledMultiscale modelling of the respiratory tract L. Baffico C. Grandmont B. Maury§ February 20, 2009 Abstract We propose here a decomposition of the respiratory tree into three stages which correspond

  11. INTRODUCTION Insects breathe using a tracheal respiratory system. The tracheal

    E-Print Network [OSTI]

    Socha, Jake

    2293 INTRODUCTION Insects breathe using a tracheal respiratory system. The tracheal system consists of the spiracular valves convectively deliver oxygen to the tissues. The tracheal respiratory system is efficient flow through the tracheal system (Harrison, 2009). During hypoxia, abdominal pumping often increases

  12. Conf Proc IEEE Eng Med Biol Soc. Author manuscript A model of ventilation used to interpret newborn lamb respiratory signals

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Mechanics ; physiology ; Sheep Introduction Respiratory problems are particularly frequent in the neonatal of the neonatal respiratory system is yet available.. Mathematical modeling, which integrates interacting respiratory dynamics. Functionally, the mammalian respiratory system is made of three components: ventilation

  13. Respiratory arsenate reductase as a bidirectional enzyme

    SciTech Connect (OSTI)

    Richey, Christine [Department of Biological Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282 (United States)] [Department of Biological Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282 (United States); Chovanec, Peter [Department of Biological Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282 (United States) [Department of Biological Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282 (United States); Department of Chemistry and Biochemistry, Duquesne University, Pittsburgh, PA 15282 (United States); Hoeft, Shelley E.; Oremland, Ronald S. [U.S. Geological Survey, 345 Middlefield Rd., MS 480, Menlo Park, CA 94025 (United States)] [U.S. Geological Survey, 345 Middlefield Rd., MS 480, Menlo Park, CA 94025 (United States); Basu, Partha [Department of Chemistry and Biochemistry, Duquesne University, Pittsburgh, PA 15282 (United States)] [Department of Chemistry and Biochemistry, Duquesne University, Pittsburgh, PA 15282 (United States); Stolz, John F., E-mail: stolz@duq.edu [Department of Biological Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282 (United States)

    2009-05-01T23:59:59.000Z

    The haloalkaliphilic bacterium Alkalilimnicola ehrlichii is capable of anaerobic chemolithoautotrophic growth by coupling the oxidation of arsenite (As(III)) to the reduction of nitrate and carbon dioxide. Analysis of its complete genome indicates that it lacks a conventional arsenite oxidase (Aox), but instead possesses two operons that each encode a putative respiratory arsenate reductase (Arr). Here we show that one homolog is expressed under chemolithoautotrophic conditions and exhibits both arsenite oxidase and arsenate reductase activity. We also demonstrate that Arr from two arsenate respiring bacteria, Alkaliphilus oremlandii and Shewanella sp. strain ANA-3, is also biochemically reversible. Thus Arr can function as a reductase or oxidase. Its physiological role in a specific organism, however, may depend on the electron potentials of the molybdenum center and [Fe-S] clusters, additional subunits, or constitution of the electron transfer chain. This versatility further underscores the ubiquity and antiquity of microbial arsenic metabolism.

  14. Chronic respiratory effects of indoor formaldehyde exposure

    SciTech Connect (OSTI)

    Krzyzanowski, M.; Quackenboss, J.J.; Lebowitz, M.D.

    1990-01-01T23:59:59.000Z

    The relation of chronic respiratory symptoms and pulmonary function to formaldehyde (HCHO) in homes was studied in a sample of 298 children (6-15 years of age) and 613 adults. HCHO measurements were made with passive samplers two one-week periods. Data on chronic cough and phlegm, wheeze, attacks of breathlessness, and doctor diagnoses of chronic bronchitis and asthma were collected with self-completed questionnaires. Peak expiratory flow rates (PEFR) were obtained during the evenings and mornings for up to 14 consecutive days for each individual. Significantly greater prevalence rates of asthma and chronic bronchitis were found in children from houses with HCHO levels 60-120 ppb than in those less exposed, especially in children also exposed to environmental tobacco smoke. In children, levels of PEFR linearly decreased with HCHO exposure, with estimated decrease due to 60 ppb of HCHO equivalent to 22% of PEFR level in nonexposed children.

  15. Respiratory disease in Utah coal miners

    SciTech Connect (OSTI)

    Rom, W.N.; Kanner, R.E.; Renzetti, A.D. Jr.; Shigeoka, J.W.; Barkman, H.W.; Nichols, M.; Turner, W.A.; Coleman, M.; Wright, W.E.

    1981-04-01T23:59:59.000Z

    Two hundred forty-two Utah underground coal miners volunteered to participate in a respiratory disease study. They were an older group (mean, 56 years of age) and had spent a mean of 29 years in the coal-mining industry. The prevalence of chronic bronchitis was 57%, and that of coal worker's pneumoconiosis, 25%; only one worker had progressive massive fibrosis. Significant impairment of pulmonary function was found among those with a history of cigarette smoking. Chronic bronchitis or coal worker's penumoconiosis among nonsmokers did not impair pulmonary function. There was a significant association among the nonsmokers between increasing exposure to coal dust and coal worker's pneumoconiosis, but not for changes in pulmonary function. Coal mine dust had a significant influence in causing the symptom complex of chronic cough and sputum production, and coal worker's pneumoconiosis.

  16. Respiratory disease in Utah coal miners

    SciTech Connect (OSTI)

    Rom, W.N.; Kanner, R.E.; Renzetti, A.D. Jr.; Shigeoka, J.W.; Barkman, H.W.; Nichols, M.; Turner, W.A.; Coleman, M.; Wright, W.E.

    1981-04-01T23:59:59.000Z

    Two hundred forty-two Utah underground coal miners volunteered to participate in a respiratory disease study. They were an older group (mean, 56 years of age) and had spent a mean of 29 years in the coal-mining industry. The prevalence of chronic bronchitis was 57%, and that of coal worker's pneumoconiosis, 25%; only one worker had progressive massive fibrosis. Significant impairment of pulmonary function was found among those with a history of cigarette smoking. Chronic bronchitis or coal worker's pneumoconiosis among nonsmokers did not impair pulmonary function. There was a significant association among the nonsmokers between increasing exposure to coal dust and coal worker's pneumoconiosis, but not for changes in pulmonary function. Coal mine dust had a significant influence in causing the symptom complex of chronic cough and sputum production, and coal worker's pneumoconiosis.

  17. BE 508: Quantitative Studies of Respiratory and Cardiovascular Systems Spring Semester, 2013

    E-Print Network [OSTI]

    Vajda, Sandor

    1 BE 508: Quantitative Studies of Respiratory and Cardiovascular Systems Spring Semester, 2013 of the respiratory system (1 lecture) (Bates, Ch 1) 2. Measurement of respiratory function (2 lectures) (Bates, Ch 2 mechanics (1 lecture) (Bates, Ch 5) 4. Inverse modeling of respiratory mechanics, part 1 (2 lectures) (Bates

  18. acute hypoxemic respiratory: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    syndrome. METHODS As shown in Figure 1 related to lower respiratory illness (e.g., cough, shortness of breath, pneumonia on x-ray, oxygen Boyer, Edmond 13 Evidence of...

  19. acute respiratory syndrome: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    syndrome. METHODS As shown in Figure 1 related to lower respiratory illness (e.g., cough, shortness of breath, pneumonia on x-ray, oxygen Boyer, Edmond 7 Management of...

  20. acute respiratory symptoms: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    syndrome. METHODS As shown in Figure 1 related to lower respiratory illness (e.g., cough, shortness of breath, pneumonia on x-ray, oxygen Boyer, Edmond 16 Evidence of...

  1. acute respiratory acidosis: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    syndrome. METHODS As shown in Figure 1 related to lower respiratory illness (e.g., cough, shortness of breath, pneumonia on x-ray, oxygen Boyer, Edmond 12 Evidence of...

  2. acute viral respiratory: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    syndrome. METHODS As shown in Figure 1 related to lower respiratory illness (e.g., cough, shortness of breath, pneumonia on x-ray, oxygen Boyer, Edmond 15 Evidence of...

  3. acute hypoxaemic respiratory: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    syndrome. METHODS As shown in Figure 1 related to lower respiratory illness (e.g., cough, shortness of breath, pneumonia on x-ray, oxygen Boyer, Edmond 11 Evidence of...

  4. acute bacterial respiratory: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    syndrome. METHODS As shown in Figure 1 related to lower respiratory illness (e.g., cough, shortness of breath, pneumonia on x-ray, oxygen Boyer, Edmond 13 Evidence of...

  5. alternative respiratory syndromes: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    syndrome. METHODS As shown in Figure 1 related to lower respiratory illness (e.g., cough, shortness of breath, pneumonia on x-ray, oxygen Boyer, Edmond 10 Management of...

  6. acute respiratory allergen: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    syndrome. METHODS As shown in Figure 1 related to lower respiratory illness (e.g., cough, shortness of breath, pneumonia on x-ray, oxygen Boyer, Edmond 11 Evidence of...

  7. acute respiratory bronchiolitis: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    syndrome. METHODS As shown in Figure 1 related to lower respiratory illness (e.g., cough, shortness of breath, pneumonia on x-ray, oxygen Boyer, Edmond 11 Evidence of...

  8. Measuring the mechanical properties of the respiratory system in patients

    E-Print Network [OSTI]

    Hayden, Nancy J.

    the lungs such that their frequency content lies in a range above that encompassed by the regular's lungs. · Only system capable of convenient, ongoing assessment of respiratory mechanical function

  9. Chronic respiratory effects of indoor formaldehyde exposure

    SciTech Connect (OSTI)

    Krzyzanowski, M.; Quackenboss, J.J.; Lebowitz, M.D. (Univ. of Arizona Health Sciences Center, Tucson (USA))

    1990-08-01T23:59:59.000Z

    The relation of chronic respiratory symptoms and pulmonary function to formaldehyde (HCHO) in homes was studied in a sample of 298 children (6-15 years of age) and 613 adults. HCHO measurements were made with passive samplers during two 1-week periods. Data on chronic cough and phlegm, wheeze, attacks of breathlessness, and doctor diagnoses of chronic bronchitis and asthma were collected with self-completed questionnaires. Peak expiratory flow rates (PEFR) were obtained during the evenings and mornings for up to 14 consecutive days for each individual. Significantly greater prevalence rates of asthma and chronic bronchitis were found in children from houses with HCHO levels 60-120 ppb than in those less exposed, especially in children also exposed to environmental tobacco smoke. In children, levels of PEFR decreased linearly with HCHO exposure, with the estimated decrease due to 60 ppb of HCHO equivalent to 22% of PEFR level in nonexposed children. The effects in asthmatic children exposed to HCHO below 50 ppb were greater than in healthy ones. The effects in adults were less evident: decrements in PEFR due to HCHO over 40 ppb were seen only in the morning, and mainly in smokers.

  10. Variations of the Respiration Signals for Respiratory-Gated Radiotherapy Using the Video Coached Respiration Guiding System

    E-Print Network [OSTI]

    Lee, Hyun Jeong; Oh, Se An

    2015-01-01T23:59:59.000Z

    Respiratory-gated radiation therapy (RGRT) has been used to minimize the dose to normal tissue in lung-cancer radiotherapy. The present research aims to improve the regularity of respiration in RGRT using a video coached respiration guiding system. In the study, 16 patients with lung cancer were evaluated. The respiration signals of the patients were measured by a real-time position management (RPM) Respiratory Gating System (Varian, USA) and the patients were trained using the video coached respiration guiding system. The patients performed free breathing and guided breathing, and the respiratory cycles were acquired for ~5 min. Then, Microsoft Excel 2010 software was used to calculate the mean and standard deviation for each phase. The standard deviation was computed in order to analyze the improvement in the respiratory regularity with respect to the period and displacement. The standard deviation of the guided breathing decreased to 65.14% in the inhale peak and 71.04% in the exhale peak compared with the...

  11. Respiratory Amplitude Guided 4-Dimensional Magnetic Resonance Imaging

    SciTech Connect (OSTI)

    Hu, Yanle, E-mail: yhu@radonc.wustl.edu [Department of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri (United States)] [Department of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri (United States); Caruthers, Shelton D. [Department of Medicine, Washington University School of Medicine, St. Louis, Missouri (United States)] [Department of Medicine, Washington University School of Medicine, St. Louis, Missouri (United States); Low, Daniel A. [Department of Radiation Oncology, University of California Los Angeles, Los Angeles, California (United States)] [Department of Radiation Oncology, University of California Los Angeles, Los Angeles, California (United States); Parikh, Parag J.; Mutic, Sasa [Department of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri (United States)] [Department of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri (United States)

    2013-05-01T23:59:59.000Z

    Purpose: To evaluate the feasibility of prospectively guiding 4-dimensional (4D) magnetic resonance imaging (MRI) image acquisition using triggers at preselected respiratory amplitudes to achieve T{sub 2} weighting for abdominal motion tracking. Methods and Materials: A respiratory amplitude-based triggering system was developed and integrated into a commercial turbo spin echo MRI sequence. Initial feasibility tests were performed on healthy human study participants. Four respiratory states, the middle and the end of inhalation and exhalation, were used to trigger 4D MRI image acquisition of the liver. To achieve T{sub 2} weighting, the echo time and repetition time were set to 75 milliseconds and 4108 milliseconds, respectively. Single-shot acquisition, together with parallel imaging and partial k-space imaging techniques, was used to improve image acquisition efficiency. 4D MRI image sets composed of axial or sagittal slices were acquired. Results: Respiratory data measured and logged by the MRI scanner showed that the triggers occurred at the appropriate respiratory levels. Liver motion could be easily observed on both 4D MRI image datasets by sensing either the change of liver in size and shape (axial) or diaphragm motion (sagittal). Both 4D MRI image datasets were T{sub 2}-weighted as expected. Conclusions: This study demonstrated the feasibility of achieving T{sub 2}-weighted 4D MRI images using amplitude-based respiratory triggers. With the aid of the respiratory amplitude-based triggering system, the proposed method is compatible with most MRI sequences and therefore has the potential to improve tumor-tissue contrast in abdominal tumor motion imaging.

  12. Human torso phantom for imaging of heart with realistic modes of cardiac and respiratory motion

    DOE Patents [OSTI]

    Boutchko, Rostyslav; Balakrishnan, Karthikayan; Gullberg, Grant T; O'Neil, James P

    2013-09-17T23:59:59.000Z

    A human torso phantom and its construction, wherein the phantom mimics respiratory and cardiac cycles in a human allowing acquisition of medical imaging data under conditions simulating patient cardiac and respiratory motion.

  13. What is the flu? Influenza, "the flu" is a contagious respiratory infection

    E-Print Network [OSTI]

    Virginia Tech

    What is the flu? Influenza, "the flu" is a contagious respiratory infection caused by the influenza medications are used. How is flu spread? The influenza virus is very contagious and is spread by respiratory

  14. INTRODUCTION Insects exchange respiratory gases through a complex network of

    E-Print Network [OSTI]

    Socha, Jake

    3409 INTRODUCTION Insects exchange respiratory gases through a complex network of tracheal tubes through the tracheal system using diffusion alone (Krogh, 1920a; Weis-Fogh, 1964), many species are known to augment gas exchange using convection (Buck, 1962; Miller, 1966a). Two general mechanisms are recognized

  15. Department of Environmental Health and Instructional Safety Respiratory Protection

    E-Print Network [OSTI]

    de Lijser, Peter

    . Seal Check. 5. Respiratory Fit Testing. 6. Inspection Procedures. 7. Cleaning and Storage Instructions example, to retard spoilage in fruit storage areas), or when oxygen is displaced by a heavier gas or vapor, ammonia, propane, etc. Some processes that use high temperatures (like welding) can involve reactions

  16. Modelling a Respiratory Central Pattern Generator Neuron in Lymnaea stagnalis

    E-Print Network [OSTI]

    Campbell, Sue Ann

    Modelling a Respiratory Central Pattern Generator Neuron in Lymnaea stagnalis Sharene D. Bungay, is characterized in part by its ability to take in oxygen both cutaneously and aerially (via its rudi- mentary lung by a 3-neuron central pattern generator (CPG) as depicted in Figure 1. Syed et al. [1, 2] were able

  17. Analysis of Cardio-respiratory Dynamics during Mental Stress using (Partial) Time-Frequency Spectra

    E-Print Network [OSTI]

    important to determine the mechanisms un- derlying stress. In this paper, we aim at studying the cardio-respiratory to conduct a combined analysis of the cardio-respiratory system. In this study, we will perform cross timeAnalysis of Cardio-respiratory Dynamics during Mental Stress using (Partial) Time-Frequency Spectra

  18. Respiratory impairment and symptoms as predictors of early retirement with disability in US underground coal miners

    SciTech Connect (OSTI)

    Ames, R.G.; Trent, R.B.

    1984-08-01T23:59:59.000Z

    A five-year prospective study of 1,394 United States underground coal miners was undertaken to study the effects of respiratory impairment on the rate of early retirement with disability (ERD). Using a logistic regression analysis, ERD was found to be related to reported persistent phlegm after adjustment was made for other respiratory symptoms, respiratory function measurements, cigarette smoking, and some demographic characteristics. No prediction of ERD occurred for spirometrically determined measures of respiratory function. The data thus give limited support to the hypothesis that early retirement with disability in underground coal miners can be predicted prospectively by measures of respiratory symptoms.

  19. Effects of inhalable particles on respiratory health of children

    SciTech Connect (OSTI)

    Dockery, D.W.; Speizer, F.E.; Stram, D.O.; Ware, J.H.; Spengler, J.D.; Ferris, B.G. Jr.

    1989-03-01T23:59:59.000Z

    Results are presented from a second cross-sectional assessment of the association of air pollution with chronic respiratory health of children participating in the Six Cities Study of Air Pollution and Health. Air pollution measurements collected at quality-controlled monitoring stations included total suspended particulates (TSP), particulate matter less than 15 microns (PM15) and 2.5 microns (PM2.5) aerodynamic diameter, fine fraction aerosol sulfate (FSO4), SO2, O3, and No2. Reported rates of chronic cough, bronchitis, and chest illness during the 1980-1981 school year were positively associated with all measures of particulate pollution (TSP, PM15, PM2.5, and FSO4) and positively but less strongly associated with concentrations of two of the gases (SO2 and NO2). Frequency of earache also tended to be associated with particulate concentrations, but no associations were found with asthma, persistent wheeze, hay fever, or nonrespiratory illness. No associations were found between pollutant concentrations and any of the pulmonary function measures considered (FVC, FEV1, FEV0.75, and MMEF). Children with a history of wheeze or asthma had a much higher prevalence of respiratory symptoms, and there was some evidence that the association between air pollutant concentrations and symptom rates was stronger among children with these markers for hyperreactive airways. These data provide further evidence that rates of respiratory illnesses and symptoms are elevated among children living in cities with high particulate pollution. They also suggest that children with hyperreactive airways may be particularly susceptible to other respiratory symptoms when exposed to these pollutants.

  20. Navajo Coal Combustion and Respiratory Health Near Shiprock, New Mexico

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Bunnell, Joseph E.; Garcia, Linda V.; Furst, Jill M.; Lerch, Harry; Olea, Ricardo A.; Suitt, Stephen E.; Kolker, Allan

    2010-01-01T23:59:59.000Z

    Indoor air pollution has been identified as a major risk factor for acute and chronic respiratory diseases throughout the world. In the sovereign Navajo Nation, an American Indian reservation located in the Four Corners area of the USA, people burn coal in their homes for heat. To explore whether/how indoor coal combustion might contribute to poor respiratory health of residents, this study examined respiratory health data, identified household risk factors such as fuel and stove type and use, analyzed samples of locally used coal, and measured and characterized fine particulate airborne matter inside selected homes. In twenty-five percent of homesmore »surveyed coal was burned in stoves not designed for that fuel, and indoor air quality was frequently found to be of a level to raise concerns. The average winter 24-hourPM2.5concentration in 20 homes was 36.0??g/m3. This is the first time thatPM2.5has been quantified and characterized inside Navajo reservation residents' homes.« less

  1. About the Air Pollution and Respiratory Health Program The Air Pollution and Respiratory Health Program of the National Center for Environmental Health, Centers for

    E-Print Network [OSTI]

    About the Air Pollution and Respiratory Health Program The Air Pollution and Respiratory Health indoor and outdoor air pollution. CDC's asthma program focuses on three main activities: (1) tracking public health agencies. For example, CDC staff are currently studying the effect of outdoor air pollution

  2. What's Trending in Breathlessness Research? Proceedings of the 8th Annual Meeting of the Breathlessness Research Interest Group

    E-Print Network [OSTI]

    Chin, C. A.; Butcher, H. Holt; Ryan, R.; Johnson, M.; Pattinson, K.; Currow, D.; Banzett, R.; Yorke, J.; Clayson, H.; Macnaughton, J.; Penfold, C.; Farquhar, M.; Booth, S.

    2015-01-01T23:59:59.000Z

    learning points already including the importance of understanding cultural differences and how these affect research. Presentation 5 Developing a complex non-pharmacological intervention for the respiratory symptom cluster of breathlessness, cough... and fatigue in lung cancer Dr Janelle Yorke In lung cancer, the respiratory distress symptom cluster of breathlessness, cough and fatigue has been described by Molassiotis et al with breathlessness usually being the driving symptom of the cluster.24...

  3. FAST-RESPONSE ISOTOPIC ALPHA CONTINUOUS AIR MONITOR (CAM)

    SciTech Connect (OSTI)

    Keith D. Patch

    2000-04-28T23:59:59.000Z

    The objective of this effort is to develop and test a novel Continuous Air Monitor (CAM) instrument for monitoring alpha-emitting radionuclides, using a technology that can be applied to Continuous Emission Monitoring (CEM) of thermal treatment system off gas streams. The CAM instrument will have very high alpha spectral resolution and provide real-time, on-line monitoring suitable for alerting workers of high concentrations of alpha-emitting radionuclides in the ambient air and for improved control of decontamination, dismantlement, and air emission control equipment. Base Phase I involves the design, development, and preliminary testing of a laboratory-scale instrument. Testing will initially be conducted using naturally-occurring radon progeny in ambient air. In the Optional Phase II, the Base Phase I instrument will be critically evaluated at the Lovelace Respiratory Research Institute (LRRI) with characterized plutonium aerosols; then an improved instrument will be built and field-tested at a suitable DOE site.

  4. Respiratory effects of diesel exhaust in salt miners

    SciTech Connect (OSTI)

    Gamble, J.F.; Jones, W.G.

    1983-09-01T23:59:59.000Z

    The respiratory health of 259 white males working at 5 salt (NaCl) mines was assessed by questionnaire, chest radiographs, and air and He-O/sup 2/ spirometry. Response variables were symptoms, pneumoconiosis, and spirometry. Predictor variables included age, height, smoking, mine, and tenure in diesel-exposed jobs. The purpose was to assess the association of response measures of respiratory health with exposure to diesel exhaust. There were only 2 cases of Grade 1 pneumoconiosis, so no further analysis was done. Comparisons within the study population showed a statistically significant dose-related association of phlegm and diesel exposure. There was a nonsignificant trend for cough and dyspnea, and no association with spirometry. Age- and smoking-adjusted rates of cough, phlegm, and dyspnea were 145, 159, and 93% of an external comparison population. Percent predicted flow rates showed statistically significant reductions, but the reductions were small and there were no dose-response relations. Percent predicted FEV1 and FVC were about 96% of predicted.

  5. Compensation du mouvement respiratoire dans les images TEP Respiratory motion correction in PET images

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Compensation du mouvement respiratoire dans les images TEP Respiratory motion correction in PET itérative. Abstract The quality of the Positron Emission Tomography (PET) is currently limited an integrated system to compensate respiratory motion in PET images. It is based on synchronous acquisition

  6. Modeling of the oxygen transfer in the respiratory process Sebastien Martin

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    in the acinar periphery. Introduction The respiratory system is designed to achieve two main functions: oxygenModeling of the oxygen transfer in the respiratory process S´ebastien Martin Laboratoire de Math, coupled with a lumped mechanical model for the ventilation process. Objectives. We aim at investigating

  7. The relationships between metabolic rate and the respiratory, circulatory and cellular mechanisms governing oxygen

    E-Print Network [OSTI]

    Hawai'i at Manoa, University of

    The relationships between metabolic rate and the respiratory, circulatory and cellular mechanisms governing oxygen transport from the respiratory medium to the tissues in air- breathing vertebrates have for albacore (Thunnus alalunga, 82­197mlkg-1). Plasma volume within the primary circulatory system (calculated

  8. Building-associated risk of febrile acute respiratory diseases in Army trainees

    SciTech Connect (OSTI)

    Brundage, J.F.; Scott, R.M.; Lednar, W.M.; Smith, D.W.; Miller, R.N.

    1988-04-08T23:59:59.000Z

    Airborne transmission of infectious agents and associations of indoor air pollutants with respiratory illnesses are well documented. We hypothesized that energy conservation measures that tighten buildings also increase risks of respiratory infection among building occupants. At four Army training centers during a 47-month period, incidence rates of febrile acute respiratory disease were compared between basic trainees in modern (energy-efficient design and construction) and old barracks. Rates of febrile acute respiratory disease were significantly higher among trainees in modern barracks (adjusted relative risk estimate, 1.51; 95% confidence interval, 1.46 to 1.56), and relative risks were consistent at the four centers. These results support the hypothesis that tight buildings with closed ventilation systems significantly increase risks of respiratory-transmitted infection among congregated, immunologically susceptible occupants.

  9. Assessment of Autonomic Control and Respiratory Sinus Arrhythmia Using Point Process Models of Human Heart Beat Dynamics

    E-Print Network [OSTI]

    Chen, Zhe

    Tracking the autonomic control and respiratory sinus arrhythmia (RSA) from electrocardiogram and respiratory measurements is an important problem in cardiovascular control. We propose a point process adaptive filter algorithm ...

  10. Pulmonary function and respiratory symptoms in potash workers

    SciTech Connect (OSTI)

    Graham, B.L.; Dosman, J.A.; Cotton, D.J.; Weisstock, S.R.; Lappi, V.G.; Froh, F.

    1984-03-01T23:59:59.000Z

    Over 94% of the workers in each of four Saskatchewan potash mines participated in a respiratory health surveillance program that included a questionnaire and pulmonary function tests. Compared with a nonexposed control group, potash workers had higher prevalences of cough, dyspnea, and chronic bronchitis but better pulmonary function. Prevalences of symptoms and pulmonary function abnormalities were similar among workers at the four mines tested and at the various job locations. Potash dust, diesel fumes, and other air contaminants may have an irritant effect that leads to the increased prevalences of cough and chronic bronchitis. Although no adverse effects of the potash mine environment on pulmonary function were found, these findings reflect a healthy worker effect or some selection process that makes the potash workers appear healthier in a cross-sectional study.

  11. Pulmonary function and respiratory symptoms in potash workers

    SciTech Connect (OSTI)

    Graham, B.L.; Dosman, J.A.; Cotton, D.J.; Weisstock, S.R.; Lappi, V.G.; Froh, F.

    1984-03-01T23:59:59.000Z

    Over 94% of the workers in each of four Saskatchewan potash mines participated in a respiratory health surveillance program that included a questionnaire and pulmonary function tests. Compared with a nonexposed control group, potash workers had higher prevalences of cough, dyspnea, and chronic bronchitis but better pulmonary function. Prevalences of symptoms and pulmonary function abnormalities were similar among workers at the four mines tested and at the various job locations. Potash dust, diesel fumes, and other air contaminants may have an irritant effect that leads to the increased prevalences of cough and chronic bronchitis. Although we found no adverse effects of the potash mine environment on pulmonary function, these findings reflect a healthy worker effect or some selection process that makes the potash workers appear healthier in a cross-sectional study.

  12. Respiratory Physiology & Neurobiology 173S (2010) S65S73 Contents lists available at ScienceDirect

    E-Print Network [OSTI]

    Socha, Jake

    2010-01-01T23:59:59.000Z

    , and control in the insect respiratory system. © 2010 Elsevier B.V. All rights reserved. 1. IntroductionRespiratory Physiology & Neurobiology 173S (2010) S65­S73 Contents lists available at ScienceDirect Respiratory Physiology & Neurobiology journal homepage: www.elsevier.com/locate/resphysiol Review Issues

  13. Nitrogen dioxide and respiratory illness in children. Part I: Health outcomes

    SciTech Connect (OSTI)

    Samet, J.M.; Lambert, W.E.; Skipper, B.J.; Cushing, A.H.; Hunt, W.C.; Young, S.A.; McLaren, L.C.; Schwab, M.; Spengler, J.D. (Univ. of New Mexico Medical Center, Albuquerque (United States))

    1993-06-01T23:59:59.000Z

    We have carried out a prospective cohort study to test the hypothesis that exposure to nitrogen dioxide increases the incidence and severity of respiratory infections during the first 18 months of life. Between January 1988 and June 1990, 1,315 infants were enrolled into the study at birth and followed with prospective surveillance for the occurrence of respiratory infections and monitoring of nitrogen dioxide concentrations in their homes. The subjects were healthy infants from homes without smokers; they were selected with stratification by type of cooking stove at a ratio of four to one for gas and electric stoves. Illness experience was monitored by a daily diary of symptoms completed by the mother and a telephone interview conducted every two weeks. Illnesses with wheezing or wet cough were classified as involving the lower respiratory tract; all other respiratory illnesses were designated as involving the upper respiratory tract. Exposure to nitrogen dioxide was estimated by two-week average concentrations measured in the subjects' bedrooms with passive samplers. This analysis is limited to the 1,205 subjects completing at least one month of observation; of these, 823 completed the full protocol, contributing 82.8% of the total number of days during which the subjects were under observation. Incidence rates for all respiratory illnesses, all upper respiratory illness, all lower respiratory illnesses, and lower respiratory illness further divided into those with any wheezing, or wet cough without wheezing, were examined within strata of nitrogen dioxide exposure at the time of the illness, nitrogen dioxide exposure during the prior month, and type of cooking stove. Consistent trends of increasing illness incidence rates with increasing exposure to nitrogen dioxide were not evident for either the lagged or unlagged exposure variables.

  14. Spirometry variability criteria--association with respiratory morbidity and mortality in a cohort of coal miners

    SciTech Connect (OSTI)

    Kellie, S.E.; Attfield, M.D.; Hankinson, J.L.; Castellan, R.M.

    1987-03-01T23:59:59.000Z

    To clarify the association between spirometry variability and respiratory morbidity and mortality, the authors analyzed data for miners examined in the first round of the National Coal Study, 1969-1971, and they compared groups of miners who failed with those who met each of two spirometry variability criteria: a 5% criterion recommended by the American Thoracic Society, and a 200 ml criterion used in prior research studies. Compared with miners who met the 5% criterion (the best two forced vital capacities must be within 5% or 100 ml of one another), the group that failed had a lower mean for forced expiratory volume in one second (FEV1), and odds ratios for cough, phlegm, wheeze, shortness of breath, and death of 1.75, 1.67, 1.76, 2.71, and 1.30, respectively. The findings for the 200 ml criterion (the best two FEV1s must be within 200 ml of one another) were somewhat different. The group that failed versus the group that met this criterion had a higher mean for FEV1, and odds ratios for cough, phlegm, wheeze, shortness of breath, and death of 1.13, 1.07, 1.15, 1.43, and 0.94, respectively. Although the findings differ for the two criteria, the findings demonstrate that increased spirometry variability is associated with poorer health.

  15. Linear and nonlinear quantification of respiratory sinus arrhythmia during propofol general anesthesia

    E-Print Network [OSTI]

    Pierce, Eric T.

    Quantitative evaluation of respiratory sinus arrhythmia (RSA) may provide important information in clinical practice of anesthesia and postoperative care. In this paper, we apply a point process method to assess dynamic ...

  16. Is breathing in infants chaotic? Dimension estimates for respiratory patterns during quiet sleep

    E-Print Network [OSTI]

    Judd, Kevin

    of Mathematics, University of Western Australia, Nedlands, Western Australia 6907; and 2Department of Respiratory Medicine, Princess Margaret Hospital for Children, Subiaco, Western Australia 6008, Australia Small, M., K

  17. acute respiratory syndrome-associated: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    syndrome. METHODS As shown in Figure 1 related to lower respiratory illness (e.g., cough, shortness of breath, pneumonia on x-ray, oxygen Boyer, Edmond 13 Evidence of...

  18. anti-severe acute respiratory: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    syndrome. METHODS As shown in Figure 1 related to lower respiratory illness (e.g., cough, shortness of breath, pneumonia on x-ray, oxygen Boyer, Edmond 11 Evidence of...

  19. Passive cigarette smoke, coal heating, and respiratory symptoms of nonsmoking women in China

    SciTech Connect (OSTI)

    Pope, C.A. III (Harvard School of Public Health, Boston, MA (United States) Brigham Young Univ., Provo, UT (United States)); Xu, X. (Harvard School of Public Health, Boston, MA (United States))

    1993-09-01T23:59:59.000Z

    In this study the authors evaluated data from a sample of 973 never-smoking women, ages 20-40, who worked in three similar textile mills in Anhui Province, China. They compared prevalence rates of respiratory symptoms across homes with and without coal heating and homes with different numbers of smokers. Multiple logistic regression models that controlled for age, job title, and mill of employment were also estimated. Respiratory symptoms were associated with combined exposure to passive cigarette smoke and coal heating. Effects of passive cigarette smoke and coal heating on respiratory symptoms appeared to be nearly additive, suggesting a dose-response relationship between respiratory symptoms and home indoor air pollution from these two sources. The prevalence of chest illness, cough, phlegm, and shortness of breath (but not wheeze) was significantly elevated for women living in homes with both smokers and coal heating.

  20. Building-related risk factors and work-related lower respiratory symptoms in 80 office buildings

    SciTech Connect (OSTI)

    Mendell, M.J.; Naco, G.M.; Wilcox, T.G.; Sieber, W.K.

    2002-01-01T23:59:59.000Z

    We assessed building-related risk factors for lower respiratory symptoms in office workers. The National Institute for Occupational Safety and Health in 1993 collected data during indoor environmental health investigations of workplaces. We used multivariate logistic regression analyses to assess relationships between lower respiratory symptoms in office workers and risk factors plausibly related to microbiologic contamination. Among 2,435 occupants in 80 office buildings, frequent, work-related multiple lower respiratory symptoms were strongly associated, in multivariate models, with two risk factors for microbiologic contamination: poor pan drainage under cooling coils and debris in outside air intake. Associations tended to be stronger among those with a history of physician-diagnosed asthma. These findings suggest that adverse lower respiratory health effects from indoor work environments, although unusual, may occur in relation to poorly designed or maintained ventilation systems, particularly among previously diagnosed asthmatics. These findings require confirmation in more representative buildings.

  1. John Widdicombeżs contribution to respiratory physiology and cough: reminiscences

    E-Print Network [OSTI]

    Chung, Kian Fan; Nadel, Jay A; Fontana, Giovanni

    2013-01-01T23:59:59.000Z

    But urge-to-cough is perplexing. I await confirmation orM, Widdicombe J: Fog-induced cough with impaired respiratoryJ: Desensitization of the cough reflex by exercise and

  2. Linking Two Seemingly Unrelated Diseases, Cancer and Acute Respiratory Distress Syndrome, Through a Dictyostelium Secreted Protein

    E-Print Network [OSTI]

    Herlihy, Sarah E

    2014-06-05T23:59:59.000Z

    the model organism Dictyostelium and the protein AprA allows us to study chalone signaling mechanisms. Acute Respiratory Distress Syndrome (ARDS) is characterized by an excess influx of neutrophils into the lungs. Neutrophils damage the lung tissue...

  3. Host-virus interactions in porcine reproductive and respiratory syndrome virus infection 

    E-Print Network [OSTI]

    Sorensen, George Edwin Peter

    2014-11-28T23:59:59.000Z

    Porcine reproductive and respiratory syndrome virus (PRRSV) is a rapidly evolving virus that has significant economic and welfare implications for the pig industry. Vaccination strategies have proved largely ineffective ...

  4. Association of residential dampness and mold with respiratory tract infections and bronchitis: a meta-analysis

    SciTech Connect (OSTI)

    Fisk, William J.; Eliseeva, Ekaterina A.; Mendell, Mark J.

    2010-11-15T23:59:59.000Z

    Dampness and mold have been shown in qualitative reviews to be associated with a variety of adverse respiratory health effects, including respiratory tract infections. Several published meta-analyses have provided quantitative summaries for some of these associations, but not for respiratory infections. Demonstrating a causal relationship between dampness-related agents, which are preventable exposures, and respiratory tract infections would suggest important new public health strategies. We report the results of quantitative meta-analyses of published studies that examined the association of dampness or mold in homes with respiratory infections and bronchitis. For primary studies meeting eligibility criteria, we transformed reported odds ratios (ORs) and confidence intervals (CIs) to the log scale. Both fixed and random effects models were applied to the log ORs and their variances. Most studies contained multiple estimated ORs. Models accounted for the correlation between multiple results within the studies analyzed. One set of analyses was performed with all eligible studies, and another set restricted to studies that controlled for age, gender, smoking, and socioeconomic status. Subgroups of studies were assessed to explore heterogeneity. Funnel plots were used to assess publication bias. The resulting summary estimates of ORs from random effects models based on all studies ranged from 1.38 to 1.50, with 95% CIs excluding the null in all cases. Use of different analysis models and restricting analyses based on control of multiple confounding variables changed findings only slightly. ORs (95% CIs) from random effects models using studies adjusting for major confounding variables were, for bronchitis, 1.45 (1.32-1.59); for respiratory infections, 1.44 (1.31-1.59); for respiratory infections excluding nonspecific upper respiratory infections, 1.50 (1.32-1.70), and for respiratory infections in children or infants, 1.48 (1.33-1.65). Little effect of publication bias was evident. Estimated attributable risk proportions ranged from 8% to 20%. Residential dampness and mold are associated with substantial and statistically significant increases in both respiratory infections and bronchitis. If these associations were confirmed as causal, effective control of dampness and mold in buildings would prevent a substantial proportion of respiratory infections.

  5. Respiratory motion management using audio-visual biofeedback for respiratory-gated radiotherapy of synchrotron-based pulsed heavy-ion beam delivery

    SciTech Connect (OSTI)

    He, Pengbo; Ma, Yuanyuan; Huang, Qiyan; Yan, Yuanlin [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Key Laboratory of Heavy Ion Radiation Biology and Medicine of Chinese Academy of Sciences, Lanzhou 730000 (China); School of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049 (China); Li, Qiang, E-mail: liqiang@impcas.ac.cn; Liu, Xinguo; Dai, Zhongying; Zhao, Ting; Fu, Tingyan; Shen, Guosheng [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Key Laboratory of Heavy Ion Radiation Biology and Medicine of Chinese Academy of Sciences, Lanzhou 730000 (China)

    2014-11-01T23:59:59.000Z

    Purpose: To efficiently deliver respiratory-gated radiation during synchrotron-based pulsed heavy-ion radiotherapy, a novel respiratory guidance method combining a personalized audio-visual biofeedback (BFB) system, breath hold (BH), and synchrotron-based gating was designed to help patients synchronize their respiratory patterns with synchrotron pulses and to overcome typical limitations such as low efficiency, residual motion, and discomfort. Methods: In-house software was developed to acquire body surface marker positions and display BFB, gating signals, and real-time beam profiles on a LED screen. Patients were prompted to perform short BHs or short deep breath holds (SDBH) with the aid of BFB following a personalized standard BH/SDBH (stBH/stSDBH) guiding curve or their own representative BH/SDBH (reBH/reSDBH) guiding curve. A practical simulation was performed for a group of 15 volunteers to evaluate the feasibility and effectiveness of this method. Effective dose rates (EDRs), mean absolute errors between the guiding curves and the measured curves, and mean absolute deviations of the measured curves were obtained within 10%–50% duty cycles (DCs) that were synchronized with the synchrotron’s flat-top phase. Results: All maneuvers for an individual volunteer took approximately half an hour, and no one experienced discomfort during the maneuvers. Using the respiratory guidance methods, the magnitude of residual motion was almost ten times less than during nongated irradiation, and increases in the average effective dose rate by factors of 2.39–4.65, 2.39–4.59, 1.73–3.50, and 1.73–3.55 for the stBH, reBH, stSDBH, and reSDBH guiding maneuvers, respectively, were observed in contrast with conventional free breathing-based gated irradiation, depending on the respiratory-gated duty cycle settings. Conclusions: The proposed respiratory guidance method with personalized BFB was confirmed to be feasible in a group of volunteers. Increased effective dose rate and improved overall treatment precision were observed compared to conventional free breathing-based, respiratory-gated irradiation. Because breathing guidance curves could be established based on the respective average respiratory period and amplitude for each patient, it may be easier for patients to cooperate using this technique.

  6. Hemolymph lactate levels and respiratory pumping behavior in the marine gastropod, Aplysia californica 

    E-Print Network [OSTI]

    Grech, Doreen Marie

    1988-01-01T23:59:59.000Z

    HEMOLYMPH LACTATE LEVELS AND RESPIRATORY PUMPING BEHAVIOR IN THE MARINE GASTROPOD, APLYSIA CALIFORNICA A Thesis by DOREEN MARIE GRECH Submitted to the Graduate College of Texas A & M University in partial fulfillment of the requirements... for the degree of MASTER OF SCIENCE August 1988 Major Subject: Biology HEMOLYMPH LACTATE LEVELS AND RESPIRATORY PUMPING BEHAVIOR IN THE MARINE GASTROPOD, APLYSIA CALIFORNICA A Thesis by DOREEN MARIE GRECH Approved as to style and content by: ames E. K z...

  7. Daily air pollution effects on children's respiratory symptoms and peak expiratory flow

    SciTech Connect (OSTI)

    Vedal, S.; Schenker, M.B.; Munoz, A.; Samet, J.M.; Batterman, S.; Speizer, F.E.

    1987-06-01T23:59:59.000Z

    To identify acute respiratory health effects associated with air pollution due to coal combustion, a subgroup of elementary school-aged children was selected from a large cross-sectional study and followed daily for eight months. Children were selected to obtain three equal-sized groups: one without respiratory symptoms, one with symptoms of persistent wheeze, and one with cough or phlegm production but without persistent wheeze. Parents completed a daily diary of symptoms from which illness constellations of upper respiratory illness (URI) and lower respiratory illness (LRI) and the symptom of wheeze were derived. Peak expiratory flow rate (PEFR) was measured daily for nine consecutive weeks during the eight-month study period. Maximum hourly concentrations of sulfur dioxide, nitrogen dioxide, ozone, and coefficient of haze for each 24-hour period, as well as minimum hourly temperature, were correlated with daily URI, LRI, wheeze, and PEFR using multiple regression models adjusting for illness occurrence or level of PEFR on the immediately preceding day. Respiratory illness on the preceding day was the most important predictor of current illness. A drop in temperature was associated with increased URI and LRI but not with increased wheeze or with a decrease in level of PEFR. No air pollutant was strongly associated with respiratory illness or with level of PEFR, either in the group of children as a whole, or in either of the symptomatic subgroups; the pollutant concentrations observed, however, were uniformly lower than current ambient air quality standards.

  8. Effects of air pollution on the respiratory health of children: a cross-sectional study

    SciTech Connect (OSTI)

    Spinaci, S.; Arossa, W.; Bugiani, M.; Natale, P.; Bucca, C.; de Candussio, G.

    1985-09-01T23:59:59.000Z

    To investigate the effects of air pollution on the respiratory health of children, a subject of some controversy, a comparative study was undertaken of 2,385 school children who lived in central urban, peripheral urban, and suburban areas. Daily monitoring of sulfur dioxide and total suspended particle concentrations in all areas showed that pollutant concentrations in central and peripheral urban areas were above commonly accepted safety levels for respiratory health, while concentrations in the suburban area were within acceptable limits. A questionnaire administered to each mother assessed environmental exposure to pollutants in the household, the occurrence of respiratory symptoms as well as lung diseases as diagnosed by a physician, and general information. Children were interviewed about smoking habits and any acute respiratory symptoms. Children also performed standard lung function tests. Results showed that children from both urban areas had lessened pulmonary function and a higher prevalence of bronchial secretion with common colds than did those from the suburban area. These differences persisted after corrections for exposure to indoor pollutants, active or passive smoking, socioeconomic status, and sex. Parental cigarette smoking was related to a fall in forced expiratory volume in 1 second and an increased incidence of acute respiratory illnesses and chronic cough in children. Although boys had higher lung volumes and lower air flow, regression analysis showed no significant influence of the interactions sex-geographic area and sex-smoking on lung function. It was concluded that air pollution has a significant effect on the respiratory health of children.

  9. Smoothing of respiratory motion traces for motion-compensated radiotherapy

    SciTech Connect (OSTI)

    Ernst, Floris; Schlaefer, Alexander; Schweikard, Achim [Institute for Robotics and Cognitive Systems, University of Luebeck, Ratzeburger Allee 160, Luebeck SH 23538 (Germany)

    2010-01-15T23:59:59.000Z

    Purpose: The CyberKnife system has been used successfully for several years to radiosurgically treat tumors without the need for stereotactic fixation or sedation of the patient. It has been shown that tumor motion in the lung, liver, and pancreas can be tracked with acceptable accuracy and repeatability. However, highly precise targeting for tumors in the lower abdomen, especially for tumors which exhibit strong motion, remains problematic. Reasons for this are manifold, like the slow tracking system operating at 26.5 Hz, and using the signal from the tracking camera ''as is''. Since the motion recorded with the camera is used to compensate for system latency by prediction and the predicted signal is subsequently used to infer the tumor position from a correlation model based on x-ray imaging of gold fiducials around the tumor, camera noise directly influences the targeting accuracy. The goal of this work is to establish the suitability of a new smoothing method for respiratory motion traces used in motion-compensated radiotherapy. The authors endeavor to show that better prediction--With a lower rms error of the predicted signal--and/or smoother prediction is possible using this method. Methods: The authors evaluated six commercially available tracking systems (NDI Aurora, PolarisClassic, Polaris Vicra, MicronTracker2 H40, FP5000, and accuTrack compact). The authors first tracked markers both stationary and while in motion to establish the systems' noise characteristics. Then the authors applied a smoothing method based on the a trous wavelet decomposition to reduce the devices' noise level. Additionally, the smoothed signal of the moving target and a motion trace from actual human respiratory motion were subjected to prediction using the MULIN and the nLMS{sub 2} algorithms. Results: The authors established that the noise distribution for a static target is Gaussian and that when the probe is moved such as to mimic human respiration, it remains Gaussian with the exception of the FP5000 and the Aurora systems. The authors also showed that the proposed smoothing method can indeed be used to filter noise. The signal's jitter dropped by as much as 95% depending on the tracking system employed. Subsequently, the 3D prediction error (rms) for a prediction horizon of 150 ms on a synthetic signal dropped by up to 37% when using a normalized LMS prediction algorithm (nLMS{sub 2}) and hardly changed when using a MULIN algorithm. When smoothing a real signal obtained in our laboratory, the improvement of prediction was similar: Up to 30% for both the nLMS{sub 2} and the best MULIN algorithm. The authors also found a noticeable increase in smoothness of the predicted signal, the relative jitter dropped by up to 95% on the real signal, and on the simulated signal. Conclusions: In conclusion, the authors can say that preprocessing of marker data is very useful in motion-compensated radiotherapy since the quality of prediction increases. This will result in better performance of the correlation model. As a side effect, since the prediction of a preprocessed signal is also less noisy, the authors expect less robot vibration resulting in better targeting accuracy and less strain on the robot gears.

  10. Respiratory triggered 4D cone-beam computed tomography: A novel method to reduce imaging dose

    SciTech Connect (OSTI)

    Cooper, Benjamin J. [Radiation Physics Laboratory, Sydney Medical School, University of Sydney, NSW 2006, Australia and Department of Medical Physics and Radiation Engineering, Canberra Hospital, Canberra, ACT 2605 (Australia); O'Brien, Ricky T.; Keall, Paul J. [Radiation Physics Laboratory, Sydney Medical School, University of Sydney, NSW 2006 (Australia); Balik, Salim; Hugo, Geoffrey D. [Radiation Oncology, Virginia Commonwealth University, 401 College Street, P.O.Box 980058, Richmond, Virginia 23298-0058 (United States)

    2013-04-15T23:59:59.000Z

    Purpose: A novel method called respiratory triggered 4D cone-beam computed tomography (RT 4D CBCT) is described whereby imaging dose can be reduced without degrading image quality. RT 4D CBCT utilizes a respiratory signal to trigger projections such that only a single projection is assigned to a given respiratory bin for each breathing cycle. In contrast, commercial 4D CBCT does not actively use the respiratory signal to minimize image dose. Methods: To compare RT 4D CBCT with conventional 4D CBCT, 3600 CBCT projections of a thorax phantom were gathered and reconstructed to generate a ground truth CBCT dataset. Simulation pairs of conventional 4D CBCT acquisitions and RT 4D CBCT acquisitions were developed assuming a sinusoidal respiratory signal which governs the selection of projections from the pool of 3600 original projections. The RT 4D CBCT acquisition triggers a single projection when the respiratory signal enters a desired acquisition bin; the conventional acquisition does not use a respiratory trigger and projections are acquired at a constant frequency. Acquisition parameters studied were breathing period, acquisition time, and imager frequency. The performance of RT 4D CBCT using phase based and displacement based sorting was also studied. Image quality was quantified by calculating difference images of the test dataset from the ground truth dataset. Imaging dose was calculated by counting projections. Results: Using phase based sorting RT 4D CBCT results in 47% less imaging dose on average compared to conventional 4D CBCT. Image quality differences were less than 4% at worst. Using displacement based sorting RT 4D CBCT results in 57% less imaging dose on average, than conventional 4D CBCT methods; however, image quality was 26% worse with RT 4D CBCT. Conclusions: Simulation studies have shown that RT 4D CBCT reduces imaging dose while maintaining comparable image quality for phase based 4D CBCT; image quality is degraded for displacement based RT 4D CBCT in its current implementation.

  11. Respiratory-Induced Prostate Motion Using Wavelet Decomposition of the Real-Time Electromagnetic Tracking Signal

    SciTech Connect (OSTI)

    Lin, Yuting [Tu and Yuen Center for Functional Onco-Imaging, Department of Radiological Sciences, University of California, Irvine, California (United States); Liu, Tian; Yang, Xiaofeng [Department of Radiation Oncology, Emory University Hospital, Winship Cancer Institute, Atlanta, Georgia (United States); Wang, Yuenan [Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, Maryland (United States); Khan, Mohammad K., E-mail: drkhurram2000@gmail.com [Department of Radiation Oncology, Emory University Hospital, Winship Cancer Institute, Atlanta, Georgia (United States)

    2013-10-01T23:59:59.000Z

    Purpose: The objective of this work is to characterize and quantify the impact of respiratory-induced prostate motion. Methods and Materials: Real-time intrafraction motion is observed with the Calypso 4-dimensional nonradioactive electromagnetic tracking system (Calypso Medical Technologies, Inc. Seattle, Washington). We report the results from a total of 1024 fractions from 31 prostate cancer patients. Wavelet transform was used to decompose the signal to extract and isolate the respiratory-induced prostate motion from the total prostate displacement. Results: Our results show that the average respiratory motion larger than 0.5 mm can be observed in 68% of the fractions. Fewer than 1% of the patients showed average respiratory motion of less than 0.2 mm, whereas 99% of the patients showed average respiratory-induced motion ranging between 0.2 and 2 mm. The maximum respiratory range of motion of 3 mm or greater was seen in only 25% of the fractions. In addition, about 2% patients showed anxiety, indicated by a breathing frequency above 24 times per minute. Conclusions: Prostate motion is influenced by respiration in most fractions. Real-time intrafraction data are sensitive enough to measure the impact of respiration by use of wavelet decomposition methods. Although the average respiratory amplitude observed in this study is small, this technique provides a tool that can be useful if one moves to smaller treatment margins (?5 mm). This also opens ups the possibility of being able to develop patient specific margins, knowing that prostate motion is not unpredictable.

  12. RESEARCH ARTICLE Open Access Computational modelling elucidates the

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    to the digestive, reproductive and respiratory systems of vertebrates [1]. Mobile or immotile cilia exist on everyRESEARCH ARTICLE Open Access Computational modelling elucidates the mechanism of ciliary regulation, nephronophthisis, situs inversus pathology or infertility. The mechanism of cilia beating regulation is complex

  13. Lung, Artificial: Current Research and Future Directions William J. Federspiel

    E-Print Network [OSTI]

    Federspiel, William J.

    Lung, Artificial: Current Research and Future Directions William J. Federspiel Robert G. Svitek University of Pittsburgh, Pittsburgh, Pennsylvania, U.S.A. INTRODUCTION Artificial lungs are medical devices designed to take over or supplement the respiratory function of the lung: oxygenating the blood

  14. RESEARCH REPORT 2012 ResearchResearchResearch

    E-Print Network [OSTI]

    Saldin, Dilano

    research on batteries and energy storage, and are part of a multimillion- dollar investment by Johnson Controls that aims to make Wisconsin a hub for energy-storage technology. #12;Chancellor's Welcome A great powerful UW-MILWAUKEE RESEARCH REPORT 2012 As Wisconsin's premier public urban institution, the University

  15. Are you protected against Pertussis? Pertussis, or whooping cough, is a highly contagious respiratory infection caused by the bacterium

    E-Print Network [OSTI]

    Are you protected against Pertussis? Pertussis, or whooping cough, is a highly contagious respiratory infection caused by the bacterium Bordetella pertussis. It causes severe coughing spells, vomiting

  16. Revision of the ICRP dosimetric model for the human respiratory tract

    SciTech Connect (OSTI)

    Bair, W.J.

    1990-12-01T23:59:59.000Z

    Although the dosimetric model of the respiratory tract used in ICRP Publication 30 had not been shown to be seriously deficient for the purpose of calculating Annual Limits on Intake (ALIs) for workers, the availability of new information led the ICRP in 1984 to create a special Task Group to review the dosimetric model of the respiratory tract and, if justified, propose revisions or a new model. The Task Group directed its efforts toward improving the model used in Publication 30 rather than developing a completely new model. The objective was a model that would facilitate calculation of biologically meaningful doses; be consistent with morphological, physiological, and radiobiological characteristics of the respiratory tract; incorporate current knowledge; meet all radiation protection needs; be user friendly by not being unnecessarily sophisticated; be adaptable to development of computer software for calculation of relevant radiation doses from knowledge of a few readily measured exposure parameters; be equally useful for assessment purposes as for calculating ALIs; be applicable to all members of the world population; and consider the influence of smoking, air pollutants, and diseases of the inhalation, deposition, and clearance of radioactive particles from the respiratory tract. The model provides for calculation of a committed dose equivalent for each region, adjusted for the relative cancer sensitivity of that region, and for the summing of these to yield a committed dose equivalent for the entire respiratory tract. 3 figs.

  17. Hamilton study: distribution of factors confounding the relationship between air quality and respiratory health

    SciTech Connect (OSTI)

    Pengelly, L.D.; Kerigan, A.T.; Goldsmith, C.H.; Inman, E.M.

    1984-10-01T23:59:59.000Z

    Hamilton, Ontario is an industrial city with a population of 300,000 which is situated at the western end of Lake Ontario. Canada's two largest iron and steel mills are located here; the city historically has had relatively poor air quality, which has improved markedly in the last 25 years. Concern about the health effects of current air quality recently led us to carry out an epidemiological study of the effects of air pollution on the respiratory health of over 3500 school children. Respiratory health was measured by pulmonary function testing of each child, and by an assessment of each child's respiratory symptoms via a questionnaire administered to the parents. Previous studies had shown that other environmental factors (e.g. parental smoking, parental cough, socioeconomic level, housing, and gas cooking) might also affect respiratory health, and thus confound any potential relationships between health and air pollution. The questionnaire also collected information on many of these confounding factors. For the purposes of initial analysis, the city was divided into five areas in which differences in air quality were expected. In general, factors which have been associated with poor respiratory health were observed to be more prevalent in areas of poorer air quality.

  18. Respiratory health effects of the indoor environment in a population of Dutch children

    SciTech Connect (OSTI)

    Dijkstra, L.; Houthuijs, D.; Brunekreef, B.; Akkerman, I.; Boleij, J.S. (Univ. of Wageningen (Netherlands))

    1990-11-01T23:59:59.000Z

    The effect of indoor exposure to nitrogen dioxide on respiratory health was studied over a period of 2 yr in a population of nonsmoking Dutch children 6 to 12 yr of age. Lung function was measured at the schools, and information on respiratory symptoms was collected from a self-administered questionnaire completed by the parents of the children. Nitrogen dioxide was measured in the homes of all children with Palmes' diffusion tubes. In addition, information on smoking and dampness in the home was collected by questionnaire. There was no relationship between exposure to nitrogen dioxide in the home and respiratory symptoms. Respiratory symptoms were found to be associated with exposure to tobacco smoke and home dampness. There was a weak, negative association between maximal midexpiratory flow (MMEF) and exposure to nitrogen dioxide. FEV1, peak expiratory flow, and MMEF were all negatively associated with exposure to tobacco smoke. Home dampness was not associated with pulmonary function. Lung function growth, measured over a period of 2 yr, was not consistently associated with any of the indoor exposure variables. The development of respiratory symptoms over time was not associated with indoor exposure to nitrogen dioxide. There was a significant association between exposure to environmental tobacco smoke in the home and the development of wheeze. There was also a significant association between home dampness and the development of cough.

  19. Cumulative exposure to arsenic and its relationship to respiratory cancer among copper-smelter employees

    SciTech Connect (OSTI)

    Lee-Feldstein, A.

    1986-01-01T23:59:59.000Z

    To explore the role of arsenic as a human carcinogen, the respiratory cancer-mortality experience (1938 to 1977) of 8045 white-male smelter employees in Montana was examined relative to cumulative exposure to arsenic trioxide and was compared with that of the white male population of the same region. Exposure to arsenic was estimated for various work areas from industrial-hygiene reports of average concentrations present in the smelter. Respiratory cancer mortality was analyzed further by time period of first employment and maximum lifetime exposure to arsenic trioxide. When exposure was estimated with arithmetic means of measured concentrations among men first employed prior to 1925, respiratory cancer mortality increased linearly with increasing cumulative exposure group, ranging from two to nine times expected; among those first employed in the period 1925 to 1947 it also increased linearly with increasing cumulative exposure group.

  20. Cumulative exposure to arsenic and its relationship to respiratory cancer among copper smelter employees

    SciTech Connect (OSTI)

    Lee-Feldstein, A.

    1986-04-01T23:59:59.000Z

    To explore the role of arsenic as a human carcinogen, the respiratory cancer mortality experience (1938 to 1977) of 8,045 while male smelter employees in Montana was examined relative to cumulative exposure to arsenic trioxide and was compared with that of the white male population of the same region. Exposure to arsenic was estimated for various work areas from industrial hygiene reports of average concentrations present in the smelter. Respiratory cancer mortality was analyzed further by time period of first employment and maximum lifetime exposure to arsenic trioxide. When exposure was estimated with arithmetic means of measured concentrations among men first employed prior to 1925, respiratory cancer mortality increased linearly with increasing cumulative exposure group, ranging from two to nine times expected; among those first employed in the period 1925 to 1947 it also increased linearly with increasing cumulative exposure group.

  1. RELATIVISTIC JETS FROM ACCRETION DISKS R.V.E. LOVELACE, P.R. GANDHI and M.M. ROMANOVA

    E-Print Network [OSTI]

    Poynting jets. Poynting jets have also been proposed to be the driving mechanism for gamma ray burst

  2. Respiratory Oxygen Uptake Is Not Decreased by an Instantaneous Elevation of [CO2], But Is Increased with

    E-Print Network [OSTI]

    DeLucia, Evan H.

    of a high-resolution dual channel oxygen analyzer within an open gas exchange system to measure respiratoryRespiratory Oxygen Uptake Is Not Decreased by an Instantaneous Elevation of [CO2], But Is Increased an instantaneous reduction of leaf dark respiration measured as CO2 efflux. No known mechanism accounts

  3. Smoking cessation among coal miners as predicted by baseline respiratory function and symptoms: a 5-year prospective study

    SciTech Connect (OSTI)

    Ames, R.G.; Hall, D.S.

    1985-03-01T23:59:59.000Z

    A prospective analysis was used to test whether respiratory impairment or the presence of respiratory symptoms predicts 5-year cigarette smoking cessation in a sample of 1,118 U.S. white, male, underground coal miners. Miners were examined in 1977 and re-examined in 1982 by NIOSH, and all miners with test abnormalities were so informed by letter. Respiratory impairment was measured by an index of airways obstruction combining the spirometric measures of Forced Vital Capacity (FVC) and Forced Expiratory Volume in 1 sec (FEV1). Bronchitis symptoms were measured by an index that combined chronic cough (3+ months/year) and chronic phlegm (3 + months/year). Among these coal miners, the presence of chronic respiratory symptoms initially was inversely associated with cigarette smoking cessation. Respiratory impairment, however, was positively associated with cigarette smoking cessation but did not reach statistical significance.

  4. SU-D-17A-07: Development and Evaluation of a Prototype Ultrasonography Respiratory Monitoring System for 4DCT Reconstruction

    SciTech Connect (OSTI)

    Yan, P; Cheng, S; Chao, C [Columbia University Medical Center, NY, NY (United States); Jain, A [New York Presbyterian Hospital, NY, NY (United States)

    2014-06-01T23:59:59.000Z

    Purpose: Respiratory motion artifacts are commonly seen in the abdominal and thoracic CT images. A Real-time Position Management (RPM) system is integrated with CT simulator using abdominal surface as a surrogate for tracking the patient respiratory motion. The respiratory-correlated four-dimensional computed tomography (4DCT) is then reconstructed by GE advantage software. However, there are still artifacts due to inaccurate respiratory motion detecting and sorting methods. We developed an Ultrasonography Respiration Monitoring (URM) system which can directly monitor diaphragm motion to detect respiratory cycles. We also developed a new 4DCT sorting and motion estimation method to reduce the respiratory motion artifacts. The new 4DCT system was compared with RPM and the GE 4DCT system. Methods: Imaging from a GE CT scanner was simultaneously correlated with both the RPM and URM to detect respiratory motion. A radiation detector, Blackcat GM-10, recorded the X-ray on/off and synchronized with URM. The diaphragm images were acquired with Ultrasonix RP system. The respiratory wave was derived from diaphragm images and synchronized with CT scanner. A more precise peaks and valleys detection tool was developed and compared with RPM. The motion is estimated for the slices which are not in the predefined respiratory phases by using block matching and optical flow method. The CT slices were then sorted into different phases and reconstructed, compared with the images reconstructed from GE Advantage software using respiratory wave produced from RPM system. Results: The 4DCT images were reconstructed for eight patients. The discontinuity at the diaphragm level due to an inaccurate identification of phases by the RPM was significantly improved by URM system. Conclusion: Our URM 4DCT system was evaluated and compared with RPM and GE 4DCT system. The new system is user friendly and able to reduce motion artifacts. It also has the potential to monitor organ motion during therapy.

  5. Respiratory disease and particulate air pollution in Santiago Chile: Contribution of erosion particles from fine sediments

    E-Print Network [OSTI]

    Commentary Respiratory disease and particulate air pollution in Santiago Chile: Contribution pollution Santiago Erosion Sedimentation a b s t r a c t Air pollution in Santiago is a serious problem for a couple of days, followed by extreme levels of air pollution. Current regulations focus mostly on PM10

  6. Lung ventilation in vertebrates is accomplished by diverse respiratory pump mechanisms. Amniotes use an aspiration

    E-Print Network [OSTI]

    Brainerd, Elizabeth

    Lung ventilation in vertebrates is accomplished by diverse respiratory pump mechanisms. Amniotes primitive body form, and a recent study of lung ventilation in Necturus maculosus has suggested that studies). The mechanism of lung ventilation in N. maculosus is similar to the buccal pump used by lepidosirenid lungfishes

  7. Prevalence of respiratory symptoms and cases suspicious for tuberculosis among public health clinic patients in Afghanistan,

    E-Print Network [OSTI]

    Scharfstein, Daniel

    , and diagnostic test results were recorded. Correlates of TB-suggestive symptoms (defined as cough >2 weeks children (age 17 or under). The TB-suggestive symptoms of cough >2 weeks and / or haemoptysis were reported workers. keywords Afghanistan, tuberculosis, respiratory symptoms, cough, sputum smear accuracy

  8. Personal exposure to nitrogen dioxide and its association with respiratory illness in Hong Kong

    SciTech Connect (OSTI)

    Koo, L.C.; Ho, J.H.; Ho, C.Y.; Matsuki, H.; Shimizu, H.; Mori, T.; Tominaga, S. (Nam Long Hospital (Hong Kong))

    1990-05-01T23:59:59.000Z

    In 1985, 362 primary schoolchildren and their 319 mothers were surveyed in Hong Kong to study the possible relationship of air pollution to respiratory illnesses. Using nitrogen dioxide (NO{sub 2}) measured by personal samplers as a measure of air pollution, the study aimed to identify the major sources of NO{sub 2} in the indoor environment and see whether its increased presence was associated with respiratory symptoms. The levels of NO{sub 2} among the mothers was found to increase by 21% if dust exposure was reported from the workplace, 18% if they used such cooking fuels as liquid petroleum gas or kerosene, 11% when kitchens did not have ventilating fans, and 10% when incense was burned at home. In terms of respiratory symptoms, an increase in NO{sub 2} levels of 19% was reported among those with allergic rhinitis and 18% among those with chronic cough. The levels of NO2 among children were correlated with levels measured in classrooms, all of which had opened windows so that the NO{sub 2} came from outdoors. No association was found between children's NO{sub 2} levels and respiratory symptoms. With the exception of smoking by the father and the children's NO{sub 2} levels, no association was found between smoking at home and NO{sub 2} levels.

  9. Pulmonary function and respiratory symptoms of school children exposed to ambient air pollution

    SciTech Connect (OSTI)

    Kim, Yoon Shin; Ko, Ung Ring [Hanyang Univ., Seoul (Korea, Republic of)

    1996-12-31T23:59:59.000Z

    This study was undertaken to evaluate the health effect of air pollution on pulmonary function and respiratory symptoms of Korean school children between 7 and 10 years of age during November 1995-January 1996. A standard respiratory symptom questionnaire was administered and spirometry was performed to examine pulmonary function of 121 children in an urban polluted area, Seoul, and of 119 children in non-polluted area, Sokcho, respectively. There was significant difference in the level of pulmonary function [forced expiratory volume in second (FEV{sub 1.0}) and forced vital capacity (FVC)] between exposed groups to polluted area and non-polluted area. Parental smoking was significantly related to respiratory symptoms of cough, phlegm, and the level of pulmonary function. The observed changes in FEV{sub 1.0} and FVC seemed to relate to home cooking fuel, not to respiratory symptoms. The additional longitudinal work that carefully monitors ambient and indoor air pollution and health effects data should be conducted to confirm these results.

  10. Evaluation of Fiber Bundle Rotation for Enhancing Gas Exchange in a Respiratory Assist Catheter

    E-Print Network [OSTI]

    Federspiel, William J.

    of a rotating densely packed bundle of hollow fiber membranes, water and blood gas exchange levels were the concept of an intravenous respiratory assist device, in which a bundle of hollow fiber membranes (HFMs short blind- ended HFMs along its length in a "bottle-brush" configura- tion.11­14 Our group first

  11. Rhythm sequence through the olfactory bulb layers during the time window of a respiratory cycle

    E-Print Network [OSTI]

    Roux, Stephane

    Rhythm sequence through the olfactory bulb layers during the time window of a respiratory cycle 07, France Keywords: LFP, olfactory bulb, oscillations, rat, synchronization Abstract The mammalian olfactory bulb is characterized by prominent oscillatory activity of its local ®eld potentials. Breathing

  12. Early respiratory dysfunction as a biomarker for epileptic encephalopathy. Katrien Jansen, MD1

    E-Print Network [OSTI]

    calculated and respiration was derived from the ECG signal. ECG-derived respiration (EDR) signals were. Results In time domain, the standard deviation of the EDR signal is significantly lower in patients respiratory rate. In frequency domain we analysed the mean power spectrum for the EDR. In patients with West

  13. ECG-Derived Respiration: Comparison and New Measures for Respiratory Variability

    E-Print Network [OSTI]

    During ECG recording, several methods can be applied to derive a respiratory signal from the ECG (EDR signal). In this paper 4 EDR methods, including ECG filtering, R and RS amplitude based techniques-derived respiration or EDR signals and arise from the movement of electrodes with respect to the heart during

  14. Theoretical evaluation on burn injury of human respiratory tract due to inhalation of

    E-Print Network [OSTI]

    Zhang, Jun

    at tissue temperature (kPa) mQ Metabolic rate of tissue (W/m3 ) R Ideal gas constant (J/molK) Re Reynolds1 Theoretical evaluation on burn injury of human respiratory tract due to inhalation of hot gas to predict the thermal impact of inhaled hot air during the early stage of fires. Influences of individual

  15. Techniques in Whole Animal Respiratory Physiology JJ Cech Jr., University of California, Davis, CA, USA

    E-Print Network [OSTI]

    Wood, Spencer

    influenced by environmental temperature and so it is not always constant within an individual. Swimming The pressure that a component of a gas mixture would have if it alone occupied the same volume at the same The movement of the respiratory medium (air or water) over the surface of the gas exchanger. Ventilation volume

  16. Modeling Respiratory Lung Motion a Biophysical Approach using Finite Element Methods

    E-Print Network [OSTI]

    Lübeck, Universität zu

    Modeling Respiratory Lung Motion ­ a Biophysical Approach using Finite Element Methods Rene Wernera motion gains in importance. In this paper a biophysical approach for modeling lung motion is described. Main aspects of the process of lung ventilation are identified and outlined as the starting point

  17. Respiratory Organ Motion and Dosimetric Impact on Breast and Nodal Irradiation

    SciTech Connect (OSTI)

    Qi, X. Sharon, E-mail: xiangrong.qi@ucdenver.ed [Department of Radiation Oncology, University of Colorado Denver, Aurora, CO (United States); White, Julia [Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI (United States); Rabinovitch, Rachel [Department of Radiation Oncology, University of Colorado Denver, Aurora, CO (United States); Merrell, Kenneth; Sood, Amit; Bauer, Anderson; Wilson, J. Frank [Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI (United States); Miften, Moyed [Department of Radiation Oncology, University of Colorado Denver, Aurora, CO (United States); Li, X. Allen [Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI (United States)

    2010-10-01T23:59:59.000Z

    Purpose: To examine the respiratory motion for target and normal structures during whole breast and nodal irradiation and the resulting dosimetric impact. Methods and Materials: Four-dimensional CT data sets of 18 patients with early-stage breast cancer were analyzed retrospectively. A three-dimensional conformal dosimetric plan designed to irradiate the breast was generated on the basis of CT images at 20% respiratory phase (reference phase). The reference plans were copied to other respiratory phases at 0% (end of inspiration) and 50% (end of expiration) to simulate the effects of breathing motion on whole breast irradiation. Dose-volume histograms, equivalent uniform dose, and normal tissue complication probability were evaluated and compared. Results: Organ motion of up to 8.8 mm was observed during free breathing. A large lung centroid movement was typically associated with a large shift of other organs. The variation of planning target volume coverage during a free breathing cycle is generally within 1%-5% (17 of 18 patients) compared with the reference plan. However, up to 28% of V{sub 45} variation for the internal mammary nodes was observed. Interphase mean dose variations of 2.2%, 1.2%, and 1.4% were observed for planning target volume, ipsilateral lung, and heart, respectively. Dose variations for the axillary nodes and brachial plexus were minimal. Conclusions: The doses delivered to the target and normal structures are different from the planned dose based on the reference phase. During normal breathing, the dosimetric impact of respiratory motion is clinically insignificant with the exception of internal mammary nodes. However, noticeable degradation in dosimetric plan quality may be expected for the patients with large respiratory motion.

  18. A cross-sectional study of secondhand smoke exposure and respiratory symptoms in non-current smokers in the U.S. trucking industry: SHS exposure and respiratory symptoms

    E-Print Network [OSTI]

    Laden, Francine; Chiu, Yueh-Hsiu; Garshick, Eric; Hammond, S; Hart, Jaime E

    2013-01-01T23:59:59.000Z

    with chronic phlegm, chronic cough, and any wheeze, defined= 1.00- 2.13) for chronic cough, 1.55 (95% CI = 1.08-2.21)respiratory symptoms, including cough, phlegm and wheeze, in

  19. A longitudinal study of respiratory symptoms in aluminum potroom workers

    SciTech Connect (OSTI)

    Kongerud, J.; Samuelsen, S.O. (Department of Thoracic Medicine, Rikshospitalet, University of Oslo (Norway))

    1991-07-01T23:59:59.000Z

    The influence of occupational work exposure and host factors on the incidence of dyspnea and wheezing as reported in questionnaires was examined in 1,301 new employees in aluminum electrolytic potrooms. The incidence appeared to decrease after 2 yr of exposure, and the estimated probability of development of symptoms was nearly 20% after 4 yr. A total of 105 subjects developed dyspnea and wheezing. Of 78 symptomatic subjects who were interviewed, 76% experienced improvement or absence of symptoms when off work. In 523 subjects who were assigned to specific levels of exposure at the end of follow-up, a dose-response gradient was found between the development of symptoms and fluoride exposure. Increased risk with increasing amounts of tobacco was also observed, but childhood allergy and a family history of asthma were not significantly related to the outcome variable. The authors conclude that both total fluoride exposure and smoking are related to asthmatic symptoms in potroom workers, and the suggestion of a dose-response gradient was found for both variables. However, a causal relationship between fluorides and symptoms should be investigated further by specific bronchial provocation testing and by research for specific antibodies and other immunologic markers.

  20. Effect of nitroimidazoles on the oxygen consumption rate and respiratory control ratio of beef heart mitochondria

    SciTech Connect (OSTI)

    Chao, C.F.; Ting, L.; Subjeck, J.R.; Johnson, R.J.

    1984-08-01T23:59:59.000Z

    The neurotoxic effect of the nitroimidazole radiosensitizers misonidazole (MISO) and desmethylmisonidazole (DMM) has seriously compromised their clinical effectiveness. The authors compare here the effect of MISO and DMM on oxygen consumption in purified beef heart mitochondria. MISO has been found to significantly increase the oxygen consumption rate and decrease the respiratory control ratio in isolated mitochondria when incubated in the presence of the NAD+ dependent substrate, ..beta..-hydroxybutyrate. DMM has a similar but less pronounced effect than MISO on these respiratory parameters. When mitochondria were incubated in the presence of these radiosensitizers for 8, 15, 30, 45, and 60 minutes, the oxygen consumption rate was decreased when succinate, a FAD dependent substrate, was added following the incubation. This decrease, which is both time and dosage dependent, is equivalent for MISO and DMM.

  1. Respiratory symptoms and lung function in oil mist-exposed workers

    SciTech Connect (OSTI)

    Jarvholm, B. (Dept.of Occupational Medicine, Gothenburg, Sweden); Bake, B.; Lavenius, B.; Thiringer, G.; Vokmann, R.

    1982-06-01T23:59:59.000Z

    The prevalence of respiratory symptoms was registered and ventilatory function was determined in 164 men exposed to oil mist. The average exposure time was 16.2 years. One hundred fifty-nine office workers served as controls. The exposed men reported more respiratory symptoms: 14% of the exposed nonsmokers v. 2% of the nonsmoking controls having cough at least three months a year. There were non significant differences between spirometric measurements and chest roentgenograms of the men exposed to oil mist and those of the office workers. The lung function of 25 nonsmoking exposed men was further examined with other lung function tests. The mean values for closing volume, slope of the alveolar plateau, total lung capacity, residual volume, elastic recoil at various lung volumes, and diffusion capacity did not differ significantly.

  2. Respiratory survey of North American Indian children living in proximity to an aluminum smelter

    SciTech Connect (OSTI)

    Ernst, P.; Thomas, D.; Becklake, M.R.

    1986-02-01T23:59:59.000Z

    We explored the relationship of respiratory symptoms and lung function to exposure to ambient air pollution consisting of particulate and gaseous fluorides. The subjects were 253 North American Indian children 11 to 17 yr of age living on the Akwasasne reserve, which is adjacent to an aluminum smelter. Among boys, closing volume (CV/VC%) was increased in those raised closest to the smelter as opposed to those having lived most of their lives farthest from this source of air pollution. In both sexes, there was a significant linear relationship between increasing CV/VC% and the amount of fluoride contained in a spot urine sample. We conclude that exposure to fluoride air pollution in the community may be associated with abnormalities in small airways. The implication of these abnormalities for future respiratory health is unknown.

  3. A cell based high-throughput screening approach for the discovery of new inhibitors of respiratory syncytial virus

    E-Print Network [OSTI]

    Chung, Dong-Hoon; Moore, Blake P.; Matharu, Daljit S.; Golden, Jennifer E.; Maddox, Clinton; Rasmussen, Lynn; Sosa, Melinda I.; Ananthan, Subramaniam; White, E. Lucile; Jia, Fuli; Jonsson, Colleen B.; Severson, William E.

    2013-01-10T23:59:59.000Z

    Background: Human respiratory syncytial virus (hRSV) is a highly contagious pathogen and is the most common cause of bronchiolitis and pneumonia for infants and children under one year of age. Worldwide, greater than 33 ...

  4. The role of vascular endothelial growth factor (VEGF) in repair and recovery from acute respiratory distress syndrome (ARDS) 

    E-Print Network [OSTI]

    Medford, Andrew R.L

    2007-01-01T23:59:59.000Z

    Acute Respiratory Distress Syndrome (ARDS) is the most extreme form of acute lung injury and continues to have a significant morbidity and mortality. Unfortunately, the mechanisms involved in the recovery and repair of ...

  5. Comments on the EPA/NIOSH guide to respiratory protection in the asbestos abatement industry

    SciTech Connect (OSTI)

    Hack, A.L.

    1987-01-01T23:59:59.000Z

    The respirators recommended by EPA and NIOSH for asbestos are not only extreme and impractical, but more important, unlikely to provide the highest protection possible. Because of the ease of wearing, powered air purifying respirators may provide as good protection as air line devices with fewer interruptions. Placing carcinogens in the category of compounds that are considered immediately dangerous to life and health (IDLH) is a mistake and leads to error in the selection of respiratory protection.

  6. The Department of Energy Respiratory Acceptance Program for Supplied-Air Suits

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2004-02-04T23:59:59.000Z

    The supplied-air suits that protect DOE contractor and federal employees from exposure to harmful atmospheres and radioactive contaminants are not included in the National Institute for Occupational Safety and Health (NIOSH) certification process for respiratory protective devices. Therefore, with the awareness and acknowledgement of NIOSH and the Occupational Safety and Health Administration (OSHA), the Department established a system for acceptance testing of supplied-air suits.

  7. Respiratory health effects associated with ambient sulfates and ozone in two rural Canadian communities

    SciTech Connect (OSTI)

    Stern, B.; Jones, L.; Raizenne, M.; Burnett, R.; Meranger, J.C.; Franklin, C.A.

    1989-06-01T23:59:59.000Z

    A cross-sectional epidemiological study investigating the respiratory health of children in two Canadian communities was conducted in 1983-1984 in Tillsonburg, Ontario, located in a region of moderately elevated concentrations of transported air pollutants, and in Portage la Prairie, Manitoba, situated in a low pollution area. There were no significant local sources of industrial emissions in either community. Seven hundred and thirty-five children aged 7-12 were studied in the first town and 895 in the second. Respiratory health was assessed by the measurement of the forced vital capacity (FVC) and forced expiratory volume in 1 sec (FEV1.0) of each child, and by evaluation of the child's respiratory symptoms and illnesses using a parent-completed questionnaire. Sulfur dioxide (SO2), sulfate, and particulate nitrate levels were significantly higher in Tillsonburg than in Portage la Prairie (P less than 0.05), but nitrogen dioxide (NO2) and inhalable particles (PM10) differed little between the communities. Historical data in the vicinity of Tillsonburg indicated that average annual levels of sulfates, total nitrates, and ozone (O3) did not vary markedly in the 9-year period preceding the study. The results show that Tillsonburg children had statistically significant (P less than 0.001) lower levels of 2% for FVC and 1.7% for FEV1.0 as compared with children in Portage la Prairie. These differences could not be explained by parental smoking or education, the use of gas cooking or wood heating fuels, pollution levels on the day of testing, or differences in age, sex, height, or weight. With the exception of inhalant allergies, which occurred more frequently in Tillsonburg children, the prevalence of chronic respiratory symptoms and illnesses was similar in the two communities.

  8. Rapid Reagentless Detection of M. tuberculosis H37Ra in Respiratory Effluents

    SciTech Connect (OSTI)

    Adams, K L; Steele, P T; Bogan, M J; Sadler, N M; Martin, S; Martin, A N; Frank, M

    2008-01-29T23:59:59.000Z

    Two similar mycobacteria, Mycobacteria tuberculosis H37Ra and Mycobacteria smegmatis are rapidly detected and identified within samples containing a complex background of respiratory effluents using Single Particle Aerosol Mass Spectrometry (SPAMS). M. tuberculosis H37Ra (TBa), an avirulent strain, is used as a surrogate for virulent tuberculosis (TBv); M. smegmatis (MSm) is utilized as a near neighbor confounder for TBa. Bovine lung surfactant and human exhaled breath condensate are used as first-order surrogates for infected human lung expirations from patients with pulmonary tuberculosis. This simulated background sputum is mixed with TBa or MSm and nebulized to produce conglomerate aerosol particles, single particles that contain a bacterium embedded within a background respiratory matrix. Mass spectra of single conglomerate particles exhibit ions associated with both respiratory effluents and mycobacteria. Spectral features distinguishing TBa from MSm in pure and conglomerate particles are shown. SPAMS pattern matching alarm algorithms are able to distinguish TBa containing particles from background matrix and MSm for >50% of the test particles, which is sufficient to enable a high probability of detection and a low false alarm rate if an adequate number of such particles are present. These results indicate the potential usefulness of SPAMS for rapid, reagentless tuberculosis screening.

  9. electronic reprint Crystallography

    E-Print Network [OSTI]

    Borgstahl, Gloria

    . Fine-'-sliced topographic data (0.002 ) stills were collected with a digital topography system Tracking reflections through cryogenic cooling with topography Jeffrey J. Lovelace, Cameron R. Murphy et al. Ż Cryogenic cooling with topography #12;research papers J. Appl. Cryst. (2006). 39, 425

  10. Occupational exposures and chronic respiratory symptoms. A population-based study

    SciTech Connect (OSTI)

    Korn, R.J.; Dockery, D.W.; Speizer, F.E.; Ware, J.H.; Ferris, B.G. Jr.

    1987-08-01T23:59:59.000Z

    Data from a random sample of 8515 white adults residing in 6 cities in the eastern and midwestern United States were used to examine the relationships between occupational exposures to dust or to gases and fumes and chronic respiratory symptoms; 31% of the population had a history of occupational dust exposure and 30% reported exposure to gas or fumes. After adjusting for smoking habits, age, gender, and city of residence, subjects with either occupational exposure had significantly elevated prevalences of chronic cough, chronic phlegm, persistent wheeze, and breathlessness. The adjusted relative odds of chronic respiratory symptoms for subjects exposed to dust ranged from 1.32 to 1.60. Subjects with gas or fume exposure had relative odds of symptoms between 1.27 and 1.43 when compared with unexposed subjects. Occupational dust exposure was associated with a higher prevalence of chronic obstructive pulmonary disease as defined by an FEV1/FVC ratio of less than 0.6, when comparing exposed and unexposed participants (OR = 1.53, 95% Cl = 1.17-2.08). Gas or fume exposure was associated with a small, but not significant, increase in COPD prevalence. Significant trends were noted for wheeze and phlegm with increasing duration of dust exposure. Although 36% of exposed subjects reported exposure to both dust and fumes, there was no evidence of a multiplicative interaction between the effects of the individual exposures. Smoking was a significant independent predictor of symptoms, but did not appear to modify the effect of dust or fumes on symptom reporting. These data, obtained in random samples of general populations, demonstrate that chronic respiratory symptoms and disease can be independently associated with occupational exposures.

  11. Air pollution and childhood respiratory health: Exposure to sulfate and ozone in 10 Canadian Rural Communities

    SciTech Connect (OSTI)

    Stern, B.R.; Raizenne, M.E.; Burnett, R.T.; Jones, L.; Kearney, J.; Franklin, C.A. (Environmental Health Directorate, Ottawa, Ontario (Canada))

    1994-08-01T23:59:59.000Z

    This study was designed to examine differences in the respiratory health status of preadolescent school children, aged 7-11 years, who resided in 10 rural Canadian communities in areas of moderate and low exposure to regional sulfate and ozone pollution. Five of the communities were located in central Saskatchewan, a low-exposure region, and five were located in southwestern Ontario, an area with moderately elevated exposures resulting from long-range atmospheric transport of polluted air masses. In this cross-sectional study, the child's respiratory symptoms and illness history were evaluated using a parent-completed questionnaire, administered in September 1985. Respiratory function was assessed once for each child in the schools between October 1985 and March 1986, by the measurement of pulmonary function for forced vital capacity (FVC), forced expiratory volume in 1 sec (FEV[sub 1.0]), peak expiratory flow rate (PEFR), mean forced expiratory flow rate during the middle half of the FVC curve (FEF[sub 25-75]), and maximal expiratory flow at 50% of the expired vital capacity (V[sub 50]max). After controlling for the effects of age, sex, parental smoking, parental education and gas cooking, no significant regional differences were observed in rates of chronic cough or phlegm, persistent wheeze, current asthma, bronchitis in the past year, or any chest illness that kept the child at home for 3 or more consecutive days during the previous year. Children living in southwestern Ontario had statistically significant (P < 0.01) mean decrements of 1.7% in FVC and 1.3% in FEV[sub 1.0] compared with Saskatchewan children, after adjusting for age, sex, weight, standing height, parental smoking, and gas cooking. There were no statistically significant regional differences in the pulmonary flow parameters (P > 0.05). 54 refs., 1 fig., 7 tabs.

  12. Occupational exposures and chronic respiratory symptoms: a population-based study

    SciTech Connect (OSTI)

    Korn, R.J.; Dockery, D.W.; Speizer, F.E.; Ware, J.H.; Ferris, B.G.

    1987-01-01T23:59:59.000Z

    Data from a random sample of 8515 white adults residing in six cities in the eastern and midwestern United States were used to examine the relationships between occupational exposures to dust or to gases and fumes and chronic respiratory symptoms. 31% of the population had a history of occupational dust exposure and 30% reported exposure to gas or to fumes. After adjusting for smoking habits, age, gender, and city of residence, subjects with either occupational exposure had significantly elevated prevalence of chronic cough, chronic phlegm, persistent wheeze, and breathlessness. The adjusted relative odds of chronic respiratory symptoms for subjects exposed to dust ranged from 1.32 to 1.60. Subjects with gas or fume exposure had relative odds of symptoms between 1.27 and 1.43 when compared to unexposed subjects. Occupational dust exposure was associated with a higher prevalence of chronic obstructive pulmonary disease (COPD) as defined by an FEV1/FVC ratio of less than 0.6, when comparing exposed and unexposed participants (OR=1.53, 95% CI=1.17-2.08). Gas or fume exposure was associated with a small, but not significant, increase in COPD prevalence. Significant trends were noted for wheeze and phlegm with increasing duration of dust exposure. Although 36% of exposed subjects reported exposure to both dust and fumes, there was no evidence of a multiplicative interaction between the effects of the individual exposures. Smoking was a significant independent predictor of symptoms, but did not appear to modify the effect of dust or fumes on symptom reporting. These data, obtained in random samples of general populations, demonstrate that chronic respiratory disease can be independently associated with occupational exposures.

  13. Coal home heating and environmental tobacco smoke in relation to lower respiratory illness in Czech children, from birth to 3 years of age

    E-Print Network [OSTI]

    2006-01-01T23:59:59.000Z

    still com- monly used in home heating and smoking rates arefound exposure to coal home heating and ETS increase youngcigarette smoke, coal heating, and respiratory symptoms of

  14. Decreased respiratory system compliance on the sixth day of mechanical ventilation is a predictor of death in patients with established acute lung injury

    E-Print Network [OSTI]

    2011-01-01T23:59:59.000Z

    with established acute lung injury. Respiratory Researchof patients with acute lung injury. Predictors of mortality.of mortality in acute lung injury during the era of lung

  15. Dosimetric evaluation of the interplay effect in respiratory-gated RapidArc radiation therapy

    SciTech Connect (OSTI)

    Riley, Craig [Department of Radiation Oncology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213 (United States)] [Department of Radiation Oncology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213 (United States); Yang, Yong, E-mail: yangy2@upmc.edu; Li, Tianfang; Zhang, Yongqian; Heron, Dwight E.; Huq, M. Saiful [Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania 15232 (United States)] [Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania 15232 (United States)

    2014-01-15T23:59:59.000Z

    Purpose: Volumetric modulated arc therapy (VMAT) with gating capability has had increasing adoption in many clinics in the United States. In this new technique, dose rate, gantry rotation speed, and the leaf motion speed of multileaf collimators (MLCs) are modulated dynamically during gated beam delivery to achieve highly conformal dose coverage of the target and normal tissue sparing. Compared with the traditional gated intensity-modulated radiation therapy technique, this complicated beam delivery technique may result in larger dose errors due to the intrafraction tumor motion. The purpose of this work is to evaluate the dosimetric influence of the interplay effect for the respiration-gated VMAT technique (RapidArc, Varian Medical Systems, Palo Alto, CA). Our work consisted of two parts: (1) Investigate the interplay effect for different target residual errors during gated RapidArc delivery using a one-dimensional moving phantom capable of producing stable sinusoidal movement; (2) Evaluate the dosimetric influence in ten clinical patients’ treatment plans using a moving phantom driven with a patient-specific respiratory curve. Methods: For the first part of this study, four plans were created with a spherical target for varying residual motion of 0.25, 0.5, 0.75, and 1.0 cm. Appropriate gating windows were applied for each. The dosimetric effect was evaluated using EDR2 film by comparing the gated delivery with static delivery. For the second part of the project, ten gated lung stereotactic body radiotherapy cases were selected and reoptimized to be delivered by the gated RapidArc technique. These plans were delivered to a phantom, and again the gated treatments were compared to static deliveries by the same methods. Results: For regular sinusoidal motion, the dose delivered to the target was not substantially affected by the gating windows when evaluated with the gamma statistics, suggesting the interplay effect has a small role in respiratory-gated RapidArc therapy. Varied results were seen when gated therapy was performed on the patient plans that could only be attributed to differences in patient respiratory patterns. Patients whose plans had the largest percentage of pixels failing the gamma statistics exhibited irregular breathing patterns including substantial interpatient variation in depth of respiration. Conclusions: The interplay effect has a limited impact on gated RapidArc therapy when evaluated with a linear phantom. Variations in patient breathing patterns, however, are of much greater clinical significance. Caution must be taken when evaluating patients’ respiratory efforts for gated arc therapy.

  16. Respiratory response of the sea anemone Bunodosoma cavernata (Bosc) to changes in temperature and salinity

    E-Print Network [OSTI]

    Retzer, Kent Arnold

    1985-01-01T23:59:59.000Z

    of Respiratory Rate . 6 2 Analysis of Variance Procedure for 0-2 Hour Average. . . 12 3 Analysis of Variance Procedure for 30 Minutes 13 Duncan's Multiple Range Test for 30 Minutes and 0-2 Hour Average and Acclimation Temperature 5 Duncan's Multiple Range... Test for 30 Minutes and 0-2 Hour Average and Experimental Temperature . 15 16 6 Duncan's Multiple Range Test for 30 Minutes and 0-2 Hour Average and Experimental Salinity 17 7 Duncan's Multiple Range Test for 30 Minutes and 0-2 Hour Average...

  17. Discriminant analysis of heart valve sounds during respiratory static volume conditions

    E-Print Network [OSTI]

    Hatzopoulos, Stavros D.

    1988-01-01T23:59:59.000Z

    oscilloscope. The respiration data was used as a marker of the subject's respiratory status and was only displayed on a 5111A TEKTRONIX oscilloscope. 88, . i. i ZZ33 46: Rr, , ii, 3'3l'0, '8z i i ZZ$3448 . :::-:-;. 8. 4. ::8i':888'88. '. . . . ::=. ::88... 100 points further. For this study the highest acceptable heart rate was set at 32 130 beats/min. This rate corresponded to a "R-R" repeti- tion of every 110 points. The detected "QRS" points were screened in two ways. First, a QRS point had...

  18. Research Statement

    E-Print Network [OSTI]

    2015-01-18T23:59:59.000Z

    entries in the natural numbers, into an undergraduate research project. ..... and developing the undergraduate research project described at the end of Section 2,

  19. Feasibility of Respiratory Triggering for MR-Guided Microwave Ablation of Liver Tumors Under General Anesthesia

    SciTech Connect (OSTI)

    Morikawa, Shigehiro, E-mail: morikawa@belle.shiga-med.ac.jp; Inubushi, Toshiro [Shiga University of Medical Science, Seta Tsukinowa-cho, Ohtsu, Molecular Neuroscience Research Center (Japan); Kurumi, Yoshimasa; Naka, Shigeyuki; Sato, Koichiro; Demura, Koichi; Tani, Tohru [Shiga University of Medical Science, Department of Surgery (Japan); Haque, Hasnine A [GE-Yokogawa Medical Systems (Japan)

    2004-08-15T23:59:59.000Z

    We obtained clear and reproducible MR fluoroscopic images and temperature maps for MR image-guided microwave ablation of liver tumors under general anesthesia without suspending the artificial ventilation. Respiratory information was directly obtained from air-way pressure without a sensor on the chest wall. The trigger signal started scanning of one whole image with a spoiled gradient echo sequence. The delay time before the start of scanning was adjusted to acquire the data corresponding to the k-space center at the maximal expiratory phase. The triggered images were apparently clearer than the nontriggered ones and the location of the liver was consistent, which made targeting of the tumor easy. MR temperature images, which were highly susceptible to the movement of the liver, during microwave ablation using a proton resonance frequency method, could be obtained without suspending the artificial ventilation. Respiratory triggering technique was found to be useful for MR fluoroscopic images and MR temperature monitoring in MR-guided microwave ablation of liver tumors under general anesthesia.

  20. Respiratory responses of vigorously exercising children to 0. 12 ppm ozone exposure

    SciTech Connect (OSTI)

    McDonnell, W.F. 3d.; Chapman, R.S.; Leigh, M.W.; Strope, G.L.; Collier, A.M.

    1985-10-01T23:59:59.000Z

    Changes in respiratory function have been suggested for children exposed to less than 0.12 ppm ozone (O3) while engaged in normal activities. Because the results of these studies have been confounded by other variables, such as temperature or the presence of other pollutants or have been questioned as to the adequacy of exposure measurements, the authors determined the acute response of children exposed to 0.12 ppm O3 in a controlled chamber environment. Twenty-three white males 8 to 11 yr of age were exposed once to clean air and once to 0.12 ppm O3 in random order. Exposures were for 2.5 h and included 2 h of intermittent heavy exercise. Measures of forced expiratory volume in one second (FEV1) and the symptom cough were determined prior to and after each exposure. A significant decline in FEV1 was found after the O3 exposure compared to the air exposure, and it appeared to persist for 16 to 20 h. No significant increase in cough was found due to O3 exposure. Forced vital capacity, specific airways resistance, respiratory frequency, tidal volume, and other symptoms were measured in a secondary exploratory analysis of this study.

  1. Association of indoor nitrogen dioxide with respiratory symptoms and pulmonary function in children

    SciTech Connect (OSTI)

    Neas, L.M.; Dockery, D.W.; Ware, J.H.; Spengler, J.D.; Speizer, F.E.; Ferris, B.G. Jr. (Harvard School of Public Health, Boston, MA (USA))

    1991-07-15T23:59:59.000Z

    The effect of indoor nitrogen dioxide on the cumulative incidence of respiratory symptoms and pulmonary function level was studied in a cohort of 1,567 white children aged 7-11 years examined in six US cities from 1983 through 1988. Week-long measurements of nitrogen dioxide were obtained at three indoor locations over 2 consecutive weeks in both the winter and the summer months. The household annual average nitrogen dioxide concentration was modeled as a continuous variable and as four ordered categories. Multiple logistic regression analysis of symptom reports from a questionnaire administered after indoor monitoring showed that a 15-ppb increase in the household annual nitrogen dioxide mean was associated with an increased cumulative incidence of lower respiratory symptoms (odds ratio (OR) = 1.4, 95% confidence interval (95% Cl) 1.1-1.7). The response variable indicated the report of one or more of the following symptoms: attacks of shortness of breath with wheeze, chronic wheeze, chronic cough, chronic phlegm, or bronchitis. Girls showed a stronger association (OR = 1.7, 95% Cl 1.3-2.2) than did boys (OR = 1.2, 95% Cl 0.9-1.5). An analysis of pulmonary function measurements showed no consistent effect of nitrogen dioxide. These results are consistent with earlier reports based on categorical indicators of household nitrogen dioxide sources and provide a more specific association with nitrogen dioxide as measured in children's homes.

  2. Respiratory symptoms among glass bottle makers exposed to stannic chloride solution and other potentially hazardous substances

    SciTech Connect (OSTI)

    Levy, B.S.; Davis, F.; Johnson, B.

    1985-04-01T23:59:59.000Z

    Concern about upper respiratory tract irritation and other symptoms among workers at a glass bottle manufacturing plant led to an epidemiologic and an industrial hygiene survey. Questionnaire responses from 35 hot end and 53 cold end workers indicated that the incidence of wheezing, chest pain, dyspnea on exertion, and cough was significantly elevated among hot end workers. Among both smokers and nonsmokers, hot end workers reported higher, but not significantly higher, rates of wheezing and chest pain. Among smokers, hot end workers reported significantly higher rates of dyspnea on exertion and cough than did cold end workers. Data suggest that reported exposure to stannic chloride solution likely caused these symptoms. The industrial hygiene survey, conducted when stannic chloride use had been reduced, cleaning had been done, and ventilation improved, focused on measuring air contaminants that might possibly cause symptoms. Levels of hydrogen chloride, which apparently was formed by the combination of stannic chloride and water in the presence of heat, were elevated. The finding of increased prevalence of respiratory symptoms among hot end workers was consistent with this exposure. Recommendations were made to reduce hazardous exposures at this plant. Individuals responsible for occupational health should be aware that relatively benign substances, such as stannic chloride and water, can combine spontaneously to form hazardous substances.

  3. Absence of respiratory effects in subjects exposed to low concentrations of TDI and MDI

    SciTech Connect (OSTI)

    Musk, A.W.; Peters, J.M.; DiBerardinis, L.; Murphy, R.L.

    1982-10-01T23:59:59.000Z

    One hundred seven subjects from a polyurethane plastic manufacturing plant have been followed over a five-year period with measurements of forced expiratory volume in 1 s (FEV1), and questionnaires on respiratory symptoms and smoking habits. Environmental concentrations of toluene diisocyanate and diphenyl methyl diisocyanate were extensively monitored to provide accurate estimates of the upper-limits of exposure of the subjects. Current mean levels of FEV1 in this population were higher than those predicted for healthy subjects. The five-year change in FEV1 did not exceed that expected from aging. No acute change in FEV1 could be demonstrated over the course of a Monday either before or after a two-week vacation. No improvement in ventilatory function was observed over the vacation period. The presence of cough or sputum was related to smoking but was not related to isocyanate exposure. The results indicate that exposure of workers to extremely low levels of isocyanates (time-weighted average concentrations of the order of 0.001 parts per million (ppm)) is not associated with chronic respiratory symptoms or effects on ventilatory capacity. The results suggest that isocyanates can be controlled to the point of eliminating effects as measured by these techniques.

  4. Health effects of acid aerosols on North American children: Respiratory symptoms

    SciTech Connect (OSTI)

    Dockery, D.W. [Harvard School of Public Health, Boston, MA (United States)]|[Channing Lab., Boston, MA (United States); Cunningham, J.; Damokosh, A.I. [Harvard School of Public Health, Boston, MA (United States)] [and others

    1996-05-01T23:59:59.000Z

    We examined the respiratory health effects of exposure to acidic air pollution among 13,369 white children 8 to 12 years old from 24 communities in the United States and Canada between 1988 and 1991. Each child`s parent or guardian completed a questionnaire. Air quality and meteorology were measured in each community for a 1-year period. We used a two-stage logistic regression model to analyze the data, adjusting for the period confounding effects of sex, history of allergies, parental asthma, parental education, and current smoking in the home. Children living in the community with the highest levels of particle strong acidity were significantly more likely [odds ratio (OR) = 1.66; 95% confidence interval (CI) 1.11-2.48] to report at least one episode of bronchitis in the past year compared to children living in the least-polluted community. Fine particulate sulfate was also associated with higher reporting of bronchitis (OR = 1.65; 95% CI 1.12-2.42). No other respiratory symptoms were significantly higher in association with any of the air pollutants of interest. No sensitive subgroups were identified. Reported bronchitis, but neither asthma, wheeze, cough, nor phlegm, were associated with levels of particle strong acidity for these children living in a nonurban environment. 26 refs., 3 figs., 4 tabs.

  5. Use of dMLC for implementation of dynamic respiratory-gated radiation therapy

    SciTech Connect (OSTI)

    Pepin, Eric W.; Wu, Huanmei [Purdue School of Engineering Technology, IUPUI, Indianapolis, Indiana 46202 (United States)] [Purdue School of Engineering Technology, IUPUI, Indianapolis, Indiana 46202 (United States); Shirato, Hiroki [Hokkaido University School of Medicine, Sapporo 060-8638 (Japan)] [Hokkaido University School of Medicine, Sapporo 060-8638 (Japan)

    2013-10-15T23:59:59.000Z

    Purpose: To simulate and evaluate the use of dynamic multileaf collimators (dMLC) in respiratory gating to compensate for baseline drift.Methods: Tumor motion tracking data from 30 lung tumors over 322 treatment fractions was analyzed with the finite state model. A dynamic respiratory gating window was established in real-time by determining the average positions during the previous two end-of-expiration breathing phases and centering the dMLC aperture on a weighted average of these positions. A simulated dMLC with physical motion constraints was used in dynamic gating treatment simulations. Fluence maps were created to provide a statistical description of radiation delivery for each fraction. Duty cycle was also calculated for each fraction.Results: The average duty cycle was 2.3% greater under dynamic gating conditions. Dynamic gating also showed higher fluences and less tumor obstruction. Additionally, dynamic gating required fewer beam toggles and each delivery period was longer on average than with static gating.Conclusions: The use of dynamic gating showed better performance than static gating and the physical constraints of a dMLC were shown to not be an impediment to dynamic gating.

  6. Buffering blood pressure fluctuations by respiratory sinus arrhythmia may in fact enhance them: a theoretical analysis

    E-Print Network [OSTI]

    Teodor Buchner; Jan ?ebrowski; Grzegorz Gielerak

    2010-07-13T23:59:59.000Z

    Using a three-compartment model of blood pressure dynamics, we analyze theoretically the short term cardiovascular variability: how the respiratory-related blood pressure fluctuations are buffered by appropriate heart rate changes: i.e. the respiratory sinus arrhythmia. The buffering is shown to be crucially dependent on the time delay between the stimulus (such as e.g. the inspiration onset) and the application of the control (the moment in time when the efferent response is delivered to the heart). This theoretical analysis shows that the buffering mechanism is effective only in the upright position of the body. It explains a paradoxical effect of enhancement of the blood pressure fluctuations by an ineffective control. Such a phenomenon was observed experimentally. Using the basis of the model, we discuss the blood pressure variability and heart rate variability under such clinical conditions as the states of expressed adrenergic drive and the tilt-test during the parasympathetic blockade or fixed rate atrial pacing. From the results of the variability analysis we draw a conclusion that the control of blood pressure in the HF band does not directly obtain the arterial baroreceptor input. We also discuss methodological issues of baroreflex sensitivity and sympathovagal balance assessment.

  7. SU-E-J-45: Design and Study of An In-House Respiratory Gating Phantom Platform for Gated Radiotherapy

    SciTech Connect (OSTI)

    Senthilkumar, S [Madurai Medical College ' Govt. Rajaji Hospital, Madurai (India)

    2014-06-01T23:59:59.000Z

    Purpose: The main purpose of this work was to develop an in-house low cost respiratory motion phantom platform for testing the accuracy of the gated radiotherapy system and analyze the dosimetric difference during gated radiotherapy. Methods: An in-house respiratory motion platform(RMP) was designed and constructed for testing the targeting accuracy of respiratory tracking system. The RMP consist of acrylic Chest Wall Platform, 2 DC motors, 4 IR sensors, speed controller circuit, 2 LED and 2 moving rods inside the RMP. The velocity of the movement can be varied from 0 to 30 cycles per minute. The platform mounted to a base using precision linear bearings. The base and platform are made of clear, 15mm thick polycarbonate plastic and the linear ball bearings are oriented to restrict the platform to a movement of approximately 50mm up and down with very little friction. Results: The targeting accuracy of the respiratory tracking system was evaluated using phantom with and without respiratory movement with varied amplitude. We have found the 5% dose difference to the PTV during the movement in comparison with stable PTV. The RMP can perform sinusoidal motion in 1D with fixed peak to peak motion of 5 to 50mm and cycle interval from 2 to 6 seconds. The RMP was designed to be able to simulate the gross anatomical anterior posterior motion attributable to respiration-induced motion of the thoracic region. Conclusion: The unique RMP simulates breathing providing the means to create a comprehensive program for commissioning, training, quality assurance and dose verification of gated radiotherapy treatments. Create the anterior/posterior movement of a target over a 5 to 50 mm distance to replicate tumor movement. The targeting error of the respiratory tracking system is less than 1.0 mm which shows suitable for clinical treatment with highly performance.

  8. Postdoctoral Research Awards Annual Research Meeting: Joseph...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Joseph Mondloch Postdoctoral Research Awards Annual Research Meeting: Joseph Mondloch Postdoctoral Research Awards Annual Research Meeting: Joseph Mondloch poster presentation....

  9. Recent studies have demonstrated that limitations to oxygen transport in lizards occur within both the respiratory and

    E-Print Network [OSTI]

    Bennett, Albert F.

    both the respiratory and cardiovascular systems. The lateral flexions of the trunk that occur during this constraint by employing an accessory ventilatory mechanism called the gular pump, thus maintaining oxygen of the main veins in the abdominal compartment. Systemic venous return and ventricular preload are major

  10. Associations of symptoms related to isocyanate, ureaformol, and formophenolic exposures with respiratory symptoms and lung function in coal miners

    SciTech Connect (OSTI)

    Bertrand, J.P.; Simon, V.; Chau, N. [Houilleres Bassin Lorraine, Freyming Merlebach (France)

    2007-04-15T23:59:59.000Z

    The respiratory effects of diphenylmethane diisocyanate (MDI)-based resins and ureaformol- and formophenolic-based resins, used in coal mining, are unknown. This cross-sectional study of 354 miners evaluated respiratory health in miners with MDI-related symptoms (IS) and ureaformol/formophenolic-related symptoms (UFS). The protocol included clinical examination, chest radiograph, questionnaire on respiratory symptoms, smoking habit, job history, resin handling, and spirometry. Resin handling concerned 27.7% of the miners. IS affected 5.6%, and 1.4% also after work. UFS affected 22.6%, and 2.3% also after work. Wheezing affected 35.6%; chronic cough, expectoration, or bronchitis about 10%; dyspnea 5.4%; and asthma 2.8%. The miners with UFS had significantly more frequent chronic cough, expectoration, chronic bronchitis, dyspnea, and wheezing, whereas those with IS at and after work had markedly lower FVC, FEV1, MMEF, FEF50% and FEF25%. These findings raise the possibility of deleterious effects of exposures to MDI and ureaformol/ ormophenolic resins on respiratory health and lung function in coal miners during their working life.

  11. Incorporation of motion information for tumour volume definition in PET Comparison of different methods of incorporating respiratory

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    , respiratory motion, super-resolution, 4D PET imaging 1. Introduction Computed tomography (CT) is routinely Tomography (PET) for diagnosis and staging, as well as the widespread availability of combined PET/CT scanners, led to numerous studies investigating the potential of PET/CT for target volume delineation. Use

  12. Effects of ambient ozone on respiratory function and symptoms in Mexico City schoolchildren

    SciTech Connect (OSTI)

    Castillejos, M.; Gold, D.R.; Dockery, D.; Tosteson, T.; Baum, T.; Speizer, F.E. (Universidad Autonoma Metropolitana-X, Mexico City, (Mexico))

    1992-02-01T23:59:59.000Z

    The effects of ambient ozone (O3) on respiratory function and acute respiratory symptoms were evaluated in 143 7- to 9-yr-old schoolchildren followed longitudinally at 1- to 2-wk intervals over a period of 6 months at three schools in Pedregal, Mexico City. The maximum O3 level exceeded the World Health Organization guideline of 80 ppb and the U.S. standard of 120 ppb in every week. For an increase from lowest to highest in the mean O3 level during the 48 hr before spirometry (53 ppb), logistic regression estimated relative odds of 1.7 for a child reporting cough/phlegm on the day of spirometry. For the full population, the mean O3 level during the hour before spirometry, not adjusted for temperature and humidity, predicted a significant decrement in FVC but not in FEV1 or FEF25-75. In contrast, the mean O3 level during the previous 24-, 48-, and 168-h periods predicted significant decrements in FEV1 and FEF25-75 but not in FVC. Ozone was consistently associated with a greater decrement in lung function for the 15 children with chronic phlegm as compared with the children without chronic cough, chronic phlegm, or wheeze. Ozone in the previous 24-, 48-, and 168-h periods predicted decrements in FEV1 for children of mothers who were current or former smokers, but not for children of mothers who were never smokers. Many of these effects were reduced in multiple regression analyses including temperature and humidity, as temperature and O3 were highly correlated.

  13. Meta-Analyses of the Associations of Respiratory Health Effectswith Dampness and Mold in Homes

    SciTech Connect (OSTI)

    Fisk, William J.; Lei-Gomez, Quanhong; Mendell, Mark J.

    2006-01-01T23:59:59.000Z

    The Institute of Medicine (IOM) of the National Academy of Sciences recently completed a critical review of the scientific literature pertaining to the association of indoor dampness and mold contamination with adverse health effects. In this paper, we report the results of quantitative meta-analysis of the studies reviewed in the IOM report. We developed point estimates and confidence intervals (CIs) to summarize the association of several respiratory and asthma-related health outcomes with the presence of dampness and mold in homes. The odds ratios and confidence intervals from the original studies were transformed to the log scale and random effect models were applied to the log odds ratios and their variance. Models were constructed both accounting for the correlation between multiple results within the studies analyzed and ignoring such potential correlation. Central estimates of ORs for the health outcomes ranged from 1.32 to 2.10, with most central estimates between 1.3 and 1.8. Confidence intervals (95%) excluded unity except in two of 28 instances, and in most cases the lower bound of the CI exceeded 1.2. In general, the two meta-analysis methods produced similar estimates for ORs and CIs. Based on the results of the meta-analyses, building dampness and mold are associated with approximately 30% to 80% increases in a variety of respiratory and asthma-related health outcomes. The results of these meta-analyses reinforce the IOM's recommendation that actions be taken to prevent and reduce building dampness problems.

  14. Effects of ambient sulfur oxides and suspended particles on respiratory health of preadolescent children

    SciTech Connect (OSTI)

    Ware, J.H.; Ferris, B.G. Jr.; Dockery, D.W.; Spengler, J.D.; Stram, D.O.; Speizer, F.E.

    1986-05-01T23:59:59.000Z

    Reported here are the results from an ongoing study of outdoor air pollution and respiratory health of children living in six cities in the eastern and midwestern United States. The study enrolled 10,106 white preadolescent children between 1974 and 1977 in 3 successive annual visits to each city. Each child received a spirometric examination, and a parent completed a standard questionnaire. Of this cohort, 8,380 children were seen for a second examination 1 yr later. An air pollution monitoring program was begun in each community at about the time of the first examination. For this report, measurements of total suspended particulates (TSP), the sulfate fraction of TSP (TSO/sub 4/), and sulfur dioxide (SO2) concentrations at study-affiliated outdoor stations were combined with measurements at other public and private monitoring sites to create a record of TSP, TSO/sub 4/, and SO/sub 2/ concentrations in each of 9 air pollution regions during the 1-yr period preceding each examination and, for TSP, during each child's lifetime up to the time of testing. Across the 6 cities, frequency of cough was significantly associated with the average of 24-h mean concentrations of all 3 air pollutants during the year preceding the health examination (p less than 0.01). Rates of bronchitis and a composite measure of lower respiratory illness were significantly associated with average particulate concentrations (p less than 0.05). In analyses restricted to lifetime residents, these outcomes were significantly associated with measures of lifetime mean TSP concentration. Within the cities, however, temporal and spatial variation in air pollutant concentrations and illness and symptom rates were not positively associated.

  15. Research in Progress The University of Edinburgh

    E-Print Network [OSTI]

    MacDonald, Andrew

    of interactions between nematode and respiratory virus infections" 1 March No RIP 8 March Leticia Alessandri Lung

  16. Microbiological Research ] (

    E-Print Network [OSTI]

    Sims, Gerald K.

    ) or to expand on previous research addressing the fate of nitrogen from agrochemicals (Bichat et al., 1999

  17. ORIGINAL RESEARCH ARTICLE published: 10 November 2014

    E-Print Network [OSTI]

    -mail: andreas.fahlman@ tamucc.edu We examined structural properties of the marine mammal respiratory system of the respiratory system in five species of pinniped under anesthesia (Pacific harbor seal, Phoca vitulina; northern of excised pinniped lungs provide a good estimate of total respiratory compliance. Keywords: lung mechanics

  18. Research Gallery

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Environmental Monitoring and Research Nanotechnology: The Science of the Small Algae to Biofuels: Squeezing Power from Pond Scum Living with Wildfire: A Shared Community...

  19. Elevated temperature triggers human respiratory syncytial virus F protein six-helix bundle formation

    SciTech Connect (OSTI)

    Yunus, Abdul S.; Jackson, Trent P.; Crisafi, Katherine; Burimski, Irina; Kilgore, Nicole R.; Zoumplis, Dorian; Allaway, Graham P.; Wild, Carl T. [Panacos Pharmaceuticals, Inc., 209 Perry Parkway, Suite 7, Gaithersburg, MD 20877 (United States); Salzwedel, Karl, E-mail: salzwedelkd@niaid.nih.go [Panacos Pharmaceuticals, Inc., 209 Perry Parkway, Suite 7, Gaithersburg, MD 20877 (United States)

    2010-01-20T23:59:59.000Z

    Human respiratory syncytial virus (RSV) is a major cause of severe lower respiratory tract infection in infants, immunocompromised patients, and the elderly. The RSV fusion (F) protein mediates fusion of the viral envelope with the target cell membrane during virus entry and is a primary target for antiviral drug and vaccine development. The F protein contains two heptad repeat regions, HR1 and HR2. Peptides corresponding to these regions form a six-helix bundle structure that is thought to play a critical role in membrane fusion. However, characterization of six-helix bundle formation in native RSV F protein has been hindered by the fact that a trigger for F protein conformational change has yet to be identified. Here we demonstrate that RSV F protein on the surface of infected cells undergoes a conformational change following exposure to elevated temperature, resulting in the formation of the six-helix bundle structure. We first generated and characterized six-helix bundle-specific antibodies raised against recombinant peptides modeling the RSV F protein six-helix bundle structure. We then used these antibodies as probes to monitor RSV F protein six-helix bundle formation in response to a diverse array of potential triggers of conformational changes. We found that exposure of 'membrane-anchored' RSV F protein to elevated temperature (45-55 deg. C) was sufficient to trigger six-helix bundle formation. Antibody binding to the six-helix bundle conformation was detected by both flow cytometry and cell-surface immunoprecipitation of the RSV F protein. None of the other treatments, including interaction with a number of potential receptors, resulted in significant binding by six-helix bundle-specific antibodies. We conclude that native, untriggered RSV F protein exists in a metastable state that can be converted in vitro to the more stable, fusogenic six-helix bundle conformation by an increase in thermal energy. These findings help to better define the mechanism of RSV F-mediated membrane fusion and have important implications for the identification of therapeutic strategies and vaccines targeting RSV F protein conformational changes.

  20. Association between occupational exposure to arsenic and neurological, respiratory and renal effects

    SciTech Connect (OSTI)

    Halatek, Tadeusz [Department of Toxicology and Carcinogenesis, Nofer Institute of Occupational Medicine, Lodz (Poland)], E-mail: halatek@imp.lodz.pl; Sinczuk-Walczak, Halina [Outpatient Clinic of Occupational Disease, Nofer Institute of Occupational Medicine, Lodz (Poland); Rabieh, Sasan [Faculty of Biology, Chemistry, and Geosciences, University of Bayreuth, Bayreuth (Germany); Wasowicz, Wojciech [Department of Toxicology and Carcinogenesis, Nofer Institute of Occupational Medicine, Lodz (Poland)

    2009-09-01T23:59:59.000Z

    Occupational exposure by inhalation in copper smelter is associated with several subclinical health phenomena. The respiratory tract is usually involved in the process of detoxication of inhaled noxious agents which, as arsenic, can act as inductors of oxidative stress (Lantz, R.C., Hays, A.M., 2006. Role of oxidative stress in arsenic-induced toxicity. Drug Metab. Rev. 38, 791-804). It is also known that irritating fumes affect distal bronchioles of non-ciliated, epithelial Clara cells, which secrete anti-inflammatory and immunosuppressive Clara cell protein (CC16) into the respiratory tract. The study group comprised 39 smelters employed at different workplaces in a copper foundry, matched for age and smoking habits with the control group (n = 16). Subjective neurological symptoms (SNS), visual evoked potentials (VEP), electroneurographic (EneG) and electroencephalographic (EEG) results were examined in the workers and the relationships between As concentration in the air (As-Air) and urine (As-U) were assessed. Effects of exposure were expressed in terms of biomarkers: CC16 as early pulmonary biomarker and {beta}{sub 2}-microglobulin ({beta}{sub 2}M) in urine and serum and retinol binding protein (RBP) as renal markers, measured by sensitive latex immunoassay. The concentrations of arsenic exceeded about two times the Threshold Limit Values (TLV) (0.01 mg/m{sup 3}). The contents of lead did not exceed the TLV (0.05 mg/m{sup 3}). Low CC16 levels in serum (12.1 {mu}g/l) of workers with SNS and VEP symptoms and highest level As-U (x{sub a} 39.0 {mu}g/l) were noted earliest in relation to occupational time. Moreover, those effects were associated with increased levels of urinary and serum {beta}{sub 2}M and urinary RBP. Results of our study suggested the initiative key role of oxidative stress in triggering the processes that eventually lead to the subclinical effects of arsenic on the nervous system.

  1. Researchers, Appointments

    E-Print Network [OSTI]

    in Aviation Gas Turbine Combustion/Emissions Research and Design System Optimization (UTIAS) Luca ScardoviInnovative Researchers, Devoted Educators Academic Appointments 2009­2012 #12;Innovative is a centre of immense inspiration, remarkable innovation and endless possibilities. And since 2009, we have

  2. Prevalence of respiratory symptoms and diseases in schoolchildren living in a polluted and in a low polluted area in Israel

    SciTech Connect (OSTI)

    Goren, A.I.; Hellmann, S.

    1988-02-01T23:59:59.000Z

    Second and fifth grade schoolchildren living in two communities with different levels of air pollution were studied. The parents of these children filled out ATS-NHLI health questionnaires. The prevalence of reported respiratory symptoms and pulmonary diseases was found to be significantly higher among children growing up in the polluted community (Ashdod) as compared with the low-pollution area (Hadera). Logistic models fitted for the respiratory conditions which differed significantly between both areas of residence also included background variables that could be responsible for these differences. Relative risk values, which were calculated from the logistic models, were in the range of 1.47 for cough without cold to 2.66 for asthma for children from Ashdod, as compared with 1.00 for children from Hadera.

  3. The Relationship Between the Prevalence of Respiratory Illness and Dermatitis and Infant Diet in the First Year of Life

    E-Print Network [OSTI]

    Kunz, Lara

    2009-04-09T23:59:59.000Z

    for asthma and allergic disease since the 12th century when a Jewish physician and philosopher, Maimonides, produced a remedy of Rhazes to ?clear the lungs of moisture, ease respiration and eliminate the cough? (32). The relationship of the environment...-wheezing lower respiratory infections included chest infection, pneumonia, whooping cough, chronic cough, or croup. As a check for reliability and validity of parental reporting of illnesses, the investigators compared 100 hospital medical records against...

  4. Postdoctoral Research Awards Annual Research Meeting: Padmaja...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Padmaja Gunda Postdoctoral Research Awards Annual Research Meeting: Padmaja Gunda Poster Presentation at 2012 EERE Annual Research Meeting, Postdoctoral Research Awards, from the...

  5. Postdoctoral Research Awards Annual Research Meeting: Brandon...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Brandon Mercado Postdoctoral Research Awards Annual Research Meeting: Brandon Mercado Poster Presentation at 2012 EERE Annual Research Meeting, Postdoctoral Research Awards, from...

  6. Relationship of respiratory symptoms and pulmonary function to tar, nicotine, and carbon monoxide yield of cigarettes

    SciTech Connect (OSTI)

    Krzyzanowski, M.; Sherrill, D.L.; Paoletti, P.; Lebowitz, M.D. (National Institute of Hygiene, Warsaw (Poland))

    1991-02-01T23:59:59.000Z

    The data from consecutive surveys of the Tucson Epidemiologic Study (1981-1988) were used to evaluate the relationship in cigarette smokers of respiratory symptoms and pulmonary function to tar, nicotine, and carbon monoxide (CO) yields of the cigarette. There were 690 subjects who reported smoking regularly in at least one survey, over age 15. After adjustment for intensity and duration of smoking and for depth of inhalation, the risk of chronic phlegm, cough, and dyspnea were not related to the tar and nicotine yields. In 414 subjects with pulmonary function tested in at least one of the three surveys the spirometric indices used were significantly related to the daily dose of tar, nicotine, and CO (product of the cigarette yield and daily number of cigarettes smoked). The effects were more pronounced for past than for current doses. However, the differentiation of pulmonary function due to various yields of cigarettes was small in comparison to the difference in pulmonary function between smokers and nonsmokers.

  7. Daily diaries of respiratory symptoms and air pollution: Methodological issues and results

    SciTech Connect (OSTI)

    Schwartz, J. (Environmental Protection Agency, Washington, DC (United States)); Wypij, D.; Dockery D.; Ware, J.; Spengler, J.; Ferris, B. Jr. (Harvard School of Public Health, Boston, MA (United States)); Zeger, S. (Johns Hopkins School of Hygiene and Public Health, Baltimore, MD (United States))

    1991-01-01T23:59:59.000Z

    Daily diaries of respiratory symptoms are a powerful technique for detecting acute effects of air pollution exposure. While conceptually simple, these diary studies can be difficult to analyze. The daily symptom rates are highly correlated, even after adjustment for covariates, and this lack of independence must be considered in the analysis. Possible approaches include the use of incidence instead of prevalence rates and autoregressive models. Heterogeneity among subjects also induces dependencies in the data. These can be addressed by stratification and by two-stage models such as those developed by Korn and Whittemore. These approaches have been applied to two data sets: a cohort of school children participating in the Harvard Six Cities Study and a cohort of student nurses in Los Angeles. Both data sets provide evidence of autocorrelation and heterogeneity. Controlling for autocorrelation corrects the precision estimates, and because diary data are usually positively autocorrelated, this leads to larger variance estimates. Controlling for heterogeneity among subjects appears to increase the effect sizes for air pollution exposure. Preliminary results indicate associations between sulfur dioxide and cough incidence in children and between nitrogen dioxide and phlegm incidence in student nurses.

  8. Effects of air pollution on children's respiratory health in three Chinese cities

    SciTech Connect (OSTI)

    Qian, Z.; Chapman, R.S.; Tian, Q.; Chen, Y.; Lioy, P.J.; Zhang, J.

    2000-04-01T23:59:59.000Z

    During the winter of 1988--1989, parents of 2,789 elementary-school students completed standardized questionnaires. The students were 5--14 y of age and were from three urban districts and one suburban district of three large Chinese cities. The 4-y average ambient levels of total suspended particles in the three cities differed greatly during the period 1985--1988: Lanzhou, 1,067 {micro}g/m{sup 3}; urban Wuhan, 406 {micro}g/m{sup 3}; Guangzhou, 296 {micro}g/m{sup 3}; and suburban Wuhan, 191 {micro}g/m{sup 3}. The authors constructed unconditional logistic-regression models to calculate odds ratios and 95% confidence intervals for prevalences of several respiratory symptoms and illnesses, adjusted for district, use of coal in the home, and parental smoking status. There was a positive and significant association between total suspended particle levels and the adjusted odds ratios for couch, phlegm, hospitalization for diseases, and pneumonia. This association was derived from only the 1,784 urban children and, therefore, the authors were unable to extrapolate it to the suburban children. The results also indicated that parental smoking status was associated with cough and phlegm, and use of coal in the home was associated only with cough prevalence.

  9. Effects of ozone on the respiratory health, allergic sensitization, and cellular immune system in children

    SciTech Connect (OSTI)

    Zwick, H.; Popp, W.; Wagner, C.; Reiser, K.; Schmoeger, J.B.; Boeck, A.H.; Herkner, K.; Radunsky, K. (Pulmonary Department, Krankenhaus Lainz, Vienna (Austria))

    1991-11-01T23:59:59.000Z

    To investigate the lasting effects of high ozone concentrations under environmental conditions, we examined the respiratory health, pulmonary function, bronchial hyperresponsiveness to methacholine, allergic sensitization, and lymphocyte subpopulations of 10- to 14-yr-old children. A total of 218 children recruited from an area with high ozone concentrations (Group A) were tested against 281 children coming from an area with low ozone concentrations (Group B). As to subjective complaints, categorized as 'usually cough with or without phlegm,' 'breathlessness,' and 'susceptibility to chest colds,' there was no difference between the two groups. The lung function parameters were similar, but in Group A subjects' bronchial hyperresponsiveness occurred more frequently and was found to be more severe than in Group B (29.4 versus 19.9%, p less than 0.02; PD20 2,100 {plus minus} 87 versus 2,350 {plus minus} 58 micrograms, p less than 0.05). In both groups the number of children who had been suffering from allergic diseases and sensitization to aeroallergens, found by means of the skin test, was the same. Comparison of the total IgE levels showed no difference at all between the two groups. As far as the white blood cells are concerned, the total and differential cell count was the same, whereas lymphocyte subpopulations showed readily recognizable changes.

  10. The respiratory health and lung function of Anglo-American children in a smelter town

    SciTech Connect (OSTI)

    Dodge, R.

    1983-02-01T23:59:59.000Z

    Cooper smelters are large, usually isolated, sources of air pollution. Arizona has several such plants on the periphery of small communities. The smelters emit predominantly sulfur oxides and particulates, and the residents of these communities intermittently are exposed to high concentrations (24-h sulfur dioxide (SO2) . 250 to 500 micrograms/m3) of smelter smoke but little other pollution. This study compared the respiratory health of Anglo-American school children who lived in one smelter community with children living in another small community in Arizona that was free of smelter air pollution. The prevalence of cough, as determined by questionnaire, was 25.6% in the smelter town children and 14.3% in the nonsmelter town children (p less than 0.05). Pulmonary function at the study onset was equal in the two groups. Over the course of the 4 yr of study, lung function growth (measured as actual forced expiratory volume in one second (FEV1) after 4 yr of study minus predicted FEV1) was also equal in the smelter town and nonsmelter town children. These results suggest that children in smelter communities have slightly more cough when compared with children living in other communities, but no differences in initial lung function or lung function at yearly testing over the period of the study.

  11. Effect of diaphragmatic fatigue on control of the respiratory muscles during CO sub 2 rebreathing

    SciTech Connect (OSTI)

    Yan, S.; Lichros, I.; Macklem, P.T. (McGill Univ., Montreal, Quebec (Canada) Montreal Chest Hospital, Quebec (Canada))

    1991-03-11T23:59:59.000Z

    The authors measured respiratory muscle recruitment and ventilation ({dot V}{sub E}) during CO{sub 2} rebreathing before and after diaphragmatic fatigue in normal subjects. Muscle activity was assessed by measuring pleural, abdominal, and transdiaphragmatic pressures (Ppl, Pab, and Pdi, resp). The results showed that (1) there was a progressive increase in Pdi with increasing end-tidal PCO{sub 2} (P{sub ET}CO{sub 2}); the rate of increase was usually greater before than after fatigue, however, in some it was less because of longer operating length and/or passive stretching of the diaphragm due to strong rib cage muscle (RCM) activity induced by fatigue; (2) Pdi increased mainly due to greater fall in Ppl; {Delta}Pab increased little during CO{sub 2} rebreathing or even decreased with P{sub ET}CO{sub 2} over 50-55 mmHg; this pattern was exaggerated by fatigue; (3) at the end of each trial, the ratio {minus}{Delta}Ppl/{Delta}Pab increased by {approximately}140% before and {approximately}850% after fatigue; (4) CO{sub 2} induced expiratory abdominal muscle activity; and (5) as a group, {dot V}{sub E} and its pattern did not change appreciably with fatigue. The authors conclude that RCM are recruited proportionately more than the diaphragm by CO{sub 2} and that diaphragmatic fatigue shifts the central drive from the fatigued diaphragm to TCM to preserve ventilation.

  12. Epidemiological-environmental study of diesel bus garage workers: chronic effects of diesel exhaust on the respiratory system

    SciTech Connect (OSTI)

    Gamble, J.; Jones, W.; Minshall, S.

    1987-10-01T23:59:59.000Z

    Two hundred and eighty-three (283) male diesel bus garage workers from four garages in two cities were examined to determine if there was excess chronic respiratory morbidity related to diesel exposure. The dependent variables were respiratory symptoms, radiographic interpretation for pneumoconiosis, and pulmonary function (FVC, FEV1, and flow rates). Independent variables included race, age, smoking, drinking, height, and tenure (as surrogate measure of exposure). Exposure-effect relationships within the study population showed no detectable associations of symptoms with tenure. There was an apparent association of pulmonary function and tenure. Seven workers (2.5%) had category 1 pneumoconiosis (three rounded opacities, two irregular opacities, and one with both rounded and irregular). The study population was also compared to a nonexposed blue-collar population. After indirect adjustment for age, race, and smoking, the study population had elevated prevalences of cough, phlegm, and wheezing, but there was no association with tenure. Dyspnea showed a dose-response trend but no apparent increase in prevalence. Mean percent predicted pulmonary function of the study population was greater than 100%, i.e., elevated above the comparison population. These data show there is an apparent effect of diesel exhaust on pulmonary function but not chest radiographs. Respiratory symptoms are high compared to blue-collar workers, but there is no relationship with tenure.

  13. Patient-specific quantification of respiratory motion-induced dose uncertainty for step-and-shoot IMRT of lung cancer

    SciTech Connect (OSTI)

    Li, Heng; Park, Peter; Liu, Wei; Matney, Jason; Balter, Peter; Zhang, Xiaodong; Li, Xiaoqiang; Zhu, X. Ronald [Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030 (United States)] [Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030 (United States); Liao, Zhongxing [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030 (United States)] [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030 (United States); Li, Yupeng [Applied Research, Varian Medical Systems, Palo Alto, California 94304 (United States)] [Applied Research, Varian Medical Systems, Palo Alto, California 94304 (United States)

    2013-12-15T23:59:59.000Z

    Purpose: The objective of this study was to quantify respiratory motion-induced dose uncertainty at the planning stage for step-and-shoot intensity-modulated radiation therapy (IMRT) using an analytical technique.Methods: Ten patients with stage II/III lung cancer who had undergone a planning four-dimensional (4D) computed tomographic scan and step-and-shoot IMRT planning were selected with a mix of motion and tumor size for this retrospective study. A step-and-shoot IMRT plan was generated for each patient. The maximum and minimum doses with respiratory motion were calculated for each plan, and the mean deviation from the 4D dose was calculated, taking delivery time, fractionation, and patient breathing cycle into consideration.Results: For all patients evaluated in this study, the mean deviation from the 4D dose in the planning target volume (PTV) was <2.5%, with a standard deviation <1.2%, and maximum point dose variation from the 4D dose was <6.2% in the PTV assuming delivery dose rate of 200 MU/min and patient breathing cycle of 8 s. The motion-induced dose uncertainty is a function of motion, fractionation, MU (plan modulation), dose rate, and patient breathing cycle.Conclusions: Respiratory motion-induced dose uncertainty varies from patient to patient. Therefore, it is important to evaluate the dose uncertainty on a patient-specific basis, which could be useful for plan evaluation and treatment strategy determination for selected patients.

  14. A multiplexed reverse transcriptase PCR assay for identification of viral respiratory pathogens at point-of-care

    SciTech Connect (OSTI)

    Letant, S E; .Ortiz, J I; Tammero, L; Birch, J M; Derlet, R W; Cohen, S; Manning, D; McBride, M T

    2007-04-11T23:59:59.000Z

    We have developed a nucleic acid-based assay that is rapid, sensitive, specific, and can be used for the simultaneous detection of 5 common human respiratory pathogens including influenza A, influenza B, parainfluenza type 1 and 3, respiratory syncytial virus, and adenovirus group B, C, and E. Typically, diagnosis on an un-extracted clinical sample can be provided in less than 3 hours, including sample collection, preparation, and processing, as well as data analysis. Such a multiplexed panel would enable rapid broad-spectrum pathogen testing on nasal swabs, and therefore allow implementation of infection control measures, and timely administration of antiviral therapies. This article presents a summary of the assay performance in terms of sensitivity and specificity. Limits of detection are provided for each targeted respiratory pathogen, and result comparisons are performed on clinical samples, our goal being to compare the sensitivity and specificity of the multiplexed assay to the combination of immunofluorescence and shell vial culture currently implemented at the UCDMC hospital. Overall, the use of the multiplexed RT-PCR assay reduced the rate of false negatives by 4% and reduced the rate of false positives by up to 10%. The assay correctly identified 99.3% of the clinical negatives, 97% of adenovirus, 95% of RSV, 92% of influenza B, and 77% of influenza A without any extraction performed on the clinical samples. The data also showed that extraction will be needed for parainfluenza virus, which was only identified correctly 24% of the time on un-extracted samples.

  15. Management of Respiratory Motion in Extracorporeal High-Intensity Focused Ultrasound Treatment in Upper Abdominal Organs: Current Status and Perspectives

    SciTech Connect (OSTI)

    Muller, A., E-mail: arnaud.muller@chu-lyon.fr [Centre Hospitalier Lyon Sud, Service de Radiologie, Hospices Civils de Lyon (France); Petrusca, L.; Auboiroux, V. [University of Geneva, Department of Radiology, Faculty of Medicine (Switzerland)] [University of Geneva, Department of Radiology, Faculty of Medicine (Switzerland); Valette, P. J. [Centre Hospitalier Lyon Sud, Service de Radiologie, Hospices Civils de Lyon (France)] [Centre Hospitalier Lyon Sud, Service de Radiologie, Hospices Civils de Lyon (France); Salomir, R. [University of Geneva, Department of Radiology, Faculty of Medicine (Switzerland)] [University of Geneva, Department of Radiology, Faculty of Medicine (Switzerland); Cotton, F. [Centre Hospitalier Lyon Sud, Service de Radiologie, Hospices Civils de Lyon (France)] [Centre Hospitalier Lyon Sud, Service de Radiologie, Hospices Civils de Lyon (France)

    2013-12-15T23:59:59.000Z

    Extracorporeal high-intensity focused ultrasound (HIFU) is a minimally invasive therapy considered with increased interest for the ablation of small tumors in deeply located organs while sparing surrounding critical tissues. A multitude of preclinical and clinical studies have showed the feasibility of the method; however, concurrently they showed several obstacles, among which the management of respiratory motion of abdominal organs is at the forefront. The aim of this review is to describe the different methods that have been proposed for managing respiratory motion and to identify their advantages and weaknesses. First, we specify the characteristics of respiratory motion for the liver, kidneys, and pancreas and the problems it causes during HIFU planning, treatment, and monitoring. Second, we make an inventory of the preclinical and clinical approaches used to overcome the problem of organ motion. Third, we analyze their respective benefits and drawbacks to identify the remaining physical, technological, and clinical challenges. We thereby consider the outlook of motion compensation techniques and those that would be the most suitable for clinical use, particularly under magnetic resonance thermometry monitoring.

  16. Research | NREL

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  17. AR Researchers

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    for fixed-wing unmanned aerial vehicles with an emphasis in cooperative unmanned vehicle research and intelligent remote sensing. Cal Christensen, M.S., P.E., P.M.P Cal...

  18. Research Areas

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  1. Research Help

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  5. Research | Energy Frontier Research Centers

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  6. Electron Transport at the Microbe–Mineral Interface: A Synthesis of Current Research Challenges

    SciTech Connect (OSTI)

    Richardson, David; Fredrickson, Jim K.; Zachara, John M.

    2012-12-01T23:59:59.000Z

    Many bacterial and archaeal species can couple growth to the respiratory reduction or oxidation of insoluble mineral oxides of transition metals. These solid substrates are abundant electron sinks and sources for life on Earth, but, since they are insoluble in water, they cannot enter the bacterial cells. So, to exploit these electron sinks and sources, specific respiratory electron-transfer mechanisms must overcome the physical limitations associated with electron transfer between a microbe and extracellular metal oxides. Recent microbiological, geochemical, biochemical, spectroscopic and structural work is beginning to shed light on the molecular mechanism and impacts of electron transfer at themicrobe–mineral interface from a nanometre to kilometre scale. The research field is attracting attention in applied quarters from those with interests in nanowires, microbial fuel cells, bioremediation and microbial cell factories.

  7. Precision-cut lung slices: a novel model for respiratory tract toxicology

    E-Print Network [OSTI]

    Schwade, Lisa Schier

    1995-01-01T23:59:59.000Z

    emphasis on in vitro techniques for toxicologic research, the precision-cut lung slice model was extended to the mouse to determine the predictive value of this system for assessing interspecies differences in metabolism and toxicity. Validation of the lung...

  8. Precision-cut lung slices: a novel model for respiratory tract toxicology 

    E-Print Network [OSTI]

    Schwade, Lisa Schier

    1995-01-01T23:59:59.000Z

    emphasis on in vitro techniques for toxicologic research, the precision-cut lung slice model was extended to the mouse to determine the predictive value of this system for assessing interspecies differences in metabolism and toxicity. Validation of the lung...

  9. Research Highlight

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  10. Research and Development with Full Scale Research

    E-Print Network [OSTI]

    Sijpheer, N.; Bakker, E.J.; Opstelten, I.

    2010-01-01T23:59:59.000Z

    One of the research programs of the Energy research Centre of the Netherlands (ECN) concerns the built environment. Several facilities to conduct the research activities are at ECN's disposal. One of these facilities, are five research dwellings...

  11. Summary of Research Instruction Research Instruction

    E-Print Network [OSTI]

    Kaji, Hajime

    for Passive corium cooling system under severe accident and reactor components (e.g. Fuel assembly, Steam Master's Program Doctoral Program Summary of Research Instruction Research Instruction Doctoral Program Summary of Research Instruction Research Instruction Application Code Name

  12. Global Health Research | 2 Global Health Research

    E-Print Network [OSTI]

    Rambaut, Andrew

    Global Health Research | 2 Global Health Research Supporting researchers in low- and middle-income countries to carry out health- related research within their own countries. Gl bal Health #12;3 | Global Health Research #12;Global Health Research | 4 We are a global charitable foundation dedicated

  13. PNNL: Research

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  17. Research Library

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  19. Research Techniques

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  20. Research Tools

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  1. UNIRIB: Research

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  2. Research Gallery

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  19. Research Highlight

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    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Scienceand Requirements Recently ApprovedReliabilityPrincipalResearch FindsASingleAssessingThe

  20. Research Highlight

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Scienceand Requirements Recently ApprovedReliabilityPrincipalResearchMaking Sense of Convective

  1. Research Library

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Scienceand Requirements Recently ApprovedReliabilityPrincipalResearchMakingHighlightsSubmitLibrary

  2. Research Projects

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Scienceand Requirements RecentlyElectronic Public Reading Room Electronic PublicResearchCurrent

  3. Research Facility,

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What's PossibleRadiation Protection Technical s o Freiberge s 3 % A PB 2 7 7 2ResearchAreas and

  4. Research Highlight

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What's PossibleRadiation Protection Technical s o Freiberge s 3 % A PB 2 7 7Research Form

  5. Research Highlight

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What's PossibleRadiation Protection Technical s o Freiberge s 3 % A PB 2 7 7Research FormImportance of

  6. Research Highlight

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What's PossibleRadiation Protection Technical s o Freiberge s 3 % A PB 2 7 7Research FormImportance

  7. Research Highlight

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What's PossibleRadiation Protection Technical s o Freiberge s 3 % A PB 2 7 7Research FormImportanceAn

  8. Research Highlight

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What's PossibleRadiation Protection Technical s o Freiberge s 3 % A PB 2 7 7Research

  9. Research Highlight

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What's PossibleRadiation Protection Technical s o Freiberge s 3 % A PB 2 7 7ResearchIntegrated Water

  10. Research Highlight

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What's PossibleRadiation Protection Technical s o Freiberge s 3 % A PB 2 7 7ResearchIntegrated

  11. Research Highlight

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What's PossibleRadiation Protection Technical s o Freiberge s 3 % A PB 2 7 7ResearchIntegratedCloud

  12. Research Highlight

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What's PossibleRadiation Protection Technical s o Freiberge s 3 % A PB 2 7 7ResearchIntegratedCloudARM

  13. Research | Photosynthetic Antenna Research Center

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclear Press ReleasesIn the Inorganic PV

  14. NREL: Biomass Research - Research Staff

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Saleshttp://www.fnal.gov/directorate/nalcal/nalcal02_07_05_files/nalcal.gifNREL NRELChemical and CatalystNewResearch Staff Find

  15. Clinical Research Unit Translating research from

    E-Print Network [OSTI]

    Bandettini, Peter A.

    Clinical Research Unit Translating research from bench to bedside www.niehs.nih.gov/clinicalunit #12;National Institute of Environmental Health Sciences Clinical Research Program The National Institute of Environmental Health Sciences (NIEHS) Clinical Research Program and the Clinical Research Unit

  16. Research and Development with Full Scale Research 

    E-Print Network [OSTI]

    Sijpheer, N.; Bakker, E.J.; Opstelten, I.

    2010-01-01T23:59:59.000Z

    One of the research programs of the Energy research Centre of the Netherlands (ECN) concerns the built environment. Several facilities to conduct the research activities are at ECN's disposal. One of these facilities, are ...

  17. Effects of Air Pollution on Respiratory Disease Asthma, closely associated with air pollution, affects nearly 15 million people in the United States, one-third of them

    E-Print Network [OSTI]

    Schladow, S. Geoffrey

    Effects of Air Pollution on Respiratory Disease Asthma, closely associated with air pollution as a greater understanding of the types of air pollutants that cause the most harm. Seminal findings, supporting a proposed update to existing air quality standards. Air pollutant ozone causes childhood asthma

  18. Domestic smoke pollution and acute respiratory infections in a rural community of the hill region of Nepal

    SciTech Connect (OSTI)

    Pandey, M.R.; Neupane, R.P.; Gautam, A.; Shrestha, I.B. (Mrigendra Medical Trust, Kathmandu (Nepal))

    1989-01-01T23:59:59.000Z

    Acute respiratory infections (ARI) are the cause of death for at least five million children per year under five years of age. Most of these deaths occur in developing countries. Domestic smoke pollution is very common in many parts of the developing world, and appropriate technology, such as smokeless stoves, is available to reduce this type of pollution. The present study has been undertaken in a rural community of the hill region of Nepal to find out if there is any association between domestic smoke pollution and ARI in infants and children younger than two years of age. This preliminary study showed that episodes of moderate and severe ARI increased with increases in the level of exposure to domestic smoke pollution, thus suggesting domestic smoke pollution to be an important, preventable risk factor of ARI.

  19. Research Frontiers Cutting-Edge Research

    E-Print Network [OSTI]

    Takada, Shoji

    Research Frontiers Cutting-Edge Research in Kyoto University Kyoto University is known. Some of them exhibit circularly polarized light (CPL) with unprecedented anisotropy factors: they emit

  20. Research Documentation Guidelines Capturing knowledge, improving research

    E-Print Network [OSTI]

    Sommerville, Ian

    researchers. The RAISER development process is an SDLC specific to Software Engineering by Computer Science

  1. Effects of Respiratory Motion on Passively Scattered Proton Therapy Versus Intensity Modulated Photon Therapy for Stage III Lung Cancer: Are Proton Plans More Sensitive to Breathing Motion?

    SciTech Connect (OSTI)

    Matney, Jason; Park, Peter C. [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); The University of Texas Graduate School of Biomedical Sciences, Houston, Texas (United States); Bluett, Jaques [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Chen, Yi Pei [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); The University of Texas Graduate School of Biomedical Sciences, Houston, Texas (United States); Liu, Wei; Court, Laurence E. [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Liao, Zhongxing [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Li, Heng [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Mohan, Radhe, E-mail: rmohan@mdanderson.org [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States)

    2013-11-01T23:59:59.000Z

    Purpose: To quantify and compare the effects of respiratory motion on paired passively scattered proton therapy (PSPT) and intensity modulated photon therapy (IMRT) plans; and to establish the relationship between the magnitude of tumor motion and the respiratory-induced dose difference for both modalities. Methods and Materials: In a randomized clinical trial comparing PSPT and IMRT, radiation therapy plans have been designed according to common planning protocols. Four-dimensional (4D) dose was computed for PSPT and IMRT plans for a patient cohort with respiratory motion ranging from 3 to 17 mm. Image registration and dose accumulation were performed using grayscale-based deformable image registration algorithms. The dose–volume histogram (DVH) differences (4D-3D [3D = 3-dimensional]) were compared for PSPT and IMRT. Changes in 4D-3D dose were correlated to the magnitude of tumor respiratory motion. Results: The average 4D-3D dose to 95% of the internal target volume was close to zero, with 19 of 20 patients within 1% of prescribed dose for both modalities. The mean 4D-3D between the 2 modalities was not statistically significant (P<.05) for all dose–volume histogram indices (mean ± SD) except the lung V5 (PSPT: +1.1% ± 0.9%; IMRT: +0.4% ± 1.2%) and maximum cord dose (PSPT: +1.5 ± 2.9 Gy; IMRT: 0.0 ± 0.2 Gy). Changes in 4D-3D dose were correlated to tumor motion for only 2 indices: dose to 95% planning target volume, and heterogeneity index. Conclusions: With our current margin formalisms, target coverage was maintained in the presence of respiratory motion up to 17 mm for both PSPT and IMRT. Only 2 of 11 4D-3D indices (lung V5 and spinal cord maximum) were statistically distinguishable between PSPT and IMRT, contrary to the notion that proton therapy will be more susceptible to respiratory motion. Because of the lack of strong correlations with 4D-3D dose differences in PSPT and IMRT, the extent of tumor motion was not an adequate predictor of potential dosimetric error caused by breathing motion.

  2. Polar lipid fatty acids, LPS-hydroxy fatty acids, and respiratory quinones of three Geobacter strains, and variation with electron acceptor

    SciTech Connect (OSTI)

    Hedrick, David B.; Peacock, Aaron; Lovley, Derek; Woodard, Trevor L.; Nevin, Kelly P.; Long, Philip E.; White, David C.

    2009-02-01T23:59:59.000Z

    The polar lipid fatty acids, lipopolysaccharide hydroxy-fatty acids, and respiratory quinones of Geobacter metallireducens str. GS-15, Geobacter sulfurreducens str. PCA, and Geobacter bemidjiensis str. Bem are reported. Also, the lipids of G. metallireducens were compared when grown with Fe3+ or nitrate as electron acceptors and G. sulfurreducens with Fe3+ or fumarate. In all experiments, the most abundant polar lipid fatty acids were 14:0, i15:0, 16:1*7c, 16:1*5c, and 16:0; lipopolysaccharide hydroxyfatty acids were dominated by 3oh16:0, 3oh14:0, 9oh16:0, and 10oh16:0; and menaquinone-8 was the most abundant respiratory quinone. Some variation in lipid proWles with strain were observed, but not with electron acceptor.

  3. Research Councils UK Transforming

    E-Print Network [OSTI]

    Berzins, M.

    Research Councils UK Transforming our energy future #12;Research funded by the Research Councils in 2002 to create a viable renewable energy research community to foster industrial engagement of research, expertise and the business capability to develop and exploit them commercially. Energy and its

  4. External Research Funding Agreements

    E-Print Network [OSTI]

    Victoria, University of

    1 External Research Funding Agreements University Policy No: RH8200 Classification: Research and university employees under Research Funding Agreements. DEFINITIONS 2.00 Research Funding Agreement means funding provided through an agreement with the university to be used for research purposes, whether

  5. Forest Research: Climate Change

    E-Print Network [OSTI]

    Forest Research: Climate Change projects Forest Research is part of the Forestry Commission of climate change-related research is wide-ranging, covering impact assessment and monitoring, adaptation around a quarter of its research budget with Forest Research on climate change and related programmes

  6. Crystallization of Mitochondrial Respiratory Complex II fromChicken Heart: A Membrane-Protein Complex Diffracting to 2.0Angstrom

    SciTech Connect (OSTI)

    Huang, Li-shar; Borders, Toni M.; Shen, John T.; Wang, Chung-Jen; Berry, Edward A.

    2004-12-17T23:59:59.000Z

    Procedure is presented for preparation of diffraction-quality crystals of a vertebrate mitochondrial respiratory Complex II. The crystals have the potential to diffract to at least 2.0 Angstrom with optimization of post-crystal-growth treatment and cryoprotection. This should allow determination of the structure of this important and medically relevant membrane protein complex at near-atomic resolution and provide great detail of the mode of binding of substrates and inhibitors at the two substrate-binding sites.

  7. Variation in rectal temperature, respiratory rate, and pulse rate of cattle as related to variations in solar radiation, air temperature, wind velocity, and vapor pressure

    E-Print Network [OSTI]

    Quazi, Mohammad Fazlur Rahim

    1955-01-01T23:59:59.000Z

    VARIATION IN RECTAL TEMPERATURE, RESPIRATORY RATE, AND PULSE RATE GF CATTLE AS RELATED TO VARIATIONS IN SOLAR RADIATION, AIR TEMPERATURE, WIND VELOCITY, AND VAPOR PRESSURE A Dissertation By Mohammad Fazlur Rahim Quazi Approved as to style... Dissertation By Mohammad Fazlur Rahim tyiazi Submitted to the Graduate School of the Agricultural and Mechanical College of Texas in partial fulfillment of the requirements for the degree of DOCTOR OF PHILOSOPHY May 1955 Major Subject: Genetics ? ?4...

  8. Daily targeting of liver tumors: Screening patients with a mock treatment and using a combination of internal and external fiducials for image-guided respiratory-gated radiotherapy

    SciTech Connect (OSTI)

    Krishnan, Sunil; Briere, Tina Marie; Dong Lei; Murthy, Ravi; Ng, Chaan; Balter, Peter; Mohan, Radhe; Gillin, Michael T.; Beddar, A. Sam [Department of Radiation Oncology, MD Anderson Cancer Center, Houston, Texas 77030 (United States); Department of Radiation Physics, MD Anderson Cancer Center, Houston, Texas 77030 (United States); Department of Diagnostic Radiology, MD Anderson Cancer Center, Houston, Texas 77030 (United States); Department of Radiation Physics, MD Anderson Cancer Center, Houston, Texas 77030 (United States)

    2007-12-15T23:59:59.000Z

    The feasibility and accuracy of using a mock treatment to screen suitable patients for respiratory-gated image-guided radiotherapy was investigated. Radio-opaque fiducials implanted adjacent to the liver tumor were used for online positioning to minimize the systematic error in patient positioning. The consistency in the degree of correlation between the external and internal fiducials was analyzed during a mock treatment. This technique could screen patients for gated therapy, reduce setup inaccuracy, and possibly individualize treatment margins.

  9. RESEARCH INFRASTRUCTURES Roadmap 2008

    E-Print Network [OSTI]

    Horn, David

    RESEARCH INFRASTRUCTURES FOR FRANCE Roadmap 2008 #12;INTRODUCTION European research infrastructures and development, benefiting to Europe's economy and competitiveness. This roadmap for the research infrastructures....................................................................................................6 3. The roadmap: existing and already decided RIs and others at the planning stage

  10. INTERNATIONAL PACIFIC RESEARCH CENTER

    E-Print Network [OSTI]

    Wang, Yuqing

    INTERNATIONAL PACIFIC RESEARCH CENTER APRIL 2004­MARCH 2005 REPORT SCHOOL OF OCEAN AND EARTH RESEARCH HIGHLIGHTS Indo-Pacific Ocean Climate Pacific Research Center Design by: Susan Yamamoto Printed by: Hagadone Printing Company Photo: Waikiki

  11. Universiteit Antwerpen Research Methods

    E-Print Network [OSTI]

    Nierstrasz, Oscar

    Methods Science vs. Engineering 5 Science Engineering Physics Chemistry Biology Mathematics ElectroUniversiteit Antwerpen Research Methods in Computer Science (Serge Demeyer -- University of Antwerp Introduction · Origins of Computer Science · Research Philosophy Research Methods · Feasibility study · Pilot

  12. Applying for Research Awards

    E-Print Network [OSTI]

    ... 53.22 KB APPLYING FOR RESEARCH AWARDS The Eastern Bird Banding Association seeks applicants for its annual $500 research awards in aid of research using banding techniques or bird banding data. ...

  13. Sandia Hydrogen Combustion Research

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Hydrogen Combustion Research Sandia Hydrogen Combustion Research Sebastian A. Kaiser (PI) Sandia National Laboratories Christopher M. White University of New Hampshire Sponsor: DoE...

  14. Nuclear Physics: Experiment Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    UserResearcher Information print version Research Highlights Public Interest Nuclear Physics Accelerator Free Electron Laser (FEL) Medical Imaging Physics Topics Campaigns...

  15. Operations Research Analyst

    Broader source: Energy.gov [DOE]

    The incumbent in this position will serve as an Operations Research Analyst in the Generation Scheduling (PGS). The Operations Research Analyst is responsible for analytical work that involves...

  16. Research at Research Development Services and

    E-Print Network [OSTI]

    · $400M ongoing upgrade · FEL Light Source (~14kW) CEBAF #12;Alternative Energy ·Algal Biodiesel Research

  17. Sandia National Laboratories: Research: Research Foundations...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Radiation Effects and High Energy Density Science Rings of Saturn, Sandia's workhorse pulsed-power machine. The Radiation Effects and High Energy Density Science Research...

  18. Induction of T helper 3 regulatory cells by dendritic cells infected with porcine reproductive and respiratory syndrome virus

    SciTech Connect (OSTI)

    Silva-Campa, Erika; Flores-Mendoza, Lilian; Resendiz, Monica; Pinelli-Saavedra, Araceli; Mata-Haro, Veronica [Centro de Investigacion en Alimentacion y Desarrollo, A.C. Hermosillo, Sonora (Mexico); Mwangi, Waithaka [Department of Veterinary Pathobiology, Texas A and M University, College Station, TX (United States); Hernandez, Jesus, E-mail: jhdez@ciad.m [Centro de Investigacion en Alimentacion y Desarrollo, A.C. Hermosillo, Sonora (Mexico)

    2009-05-10T23:59:59.000Z

    Delayed development of virus-specific immune response has been observed in pigs infected with the porcine reproductive and respiratory syndrome virus (PRRSV). Several studies support the hypothesis that the PRRSV is capable of modulating porcine immune system, but the mechanisms involved are yet to be defined. In this study, we evaluated the induction of T regulatory cells by PRRSV-infected dendritic cells (DCs). Our results showed that PRRSV-infected DCs significantly increased Foxp3{sup +}CD25{sup +} T cells, an effect that was reversible by IFN-alpha treatment, and this outcome was reproducible using two distinct PRRSV strains. Analysis of the expressed cytokines suggested that the induction of Foxp3{sup +}CD25{sup +} T cells is dependent on TGF-beta but not IL-10. In addition, a significant up-regulation of Foxp3 mRNA, but not TBX21 or GATA3, was detected. Importantly, our results showed that the induced Foxp3{sup +}CD25{sup +} T cells were able to suppress the proliferation of PHA-stimulated PBMCs. The T cells induced by the PRRSV-infected DCs fit the Foxp3{sup +}CD25{sup +} T helper 3 (Th3) regulatory cell phenotype described in the literature. The induction of this cell phenotype depended, at least in part, on PRRSV viability because IFN-alpha treatment or virus inactivation reversed these effects. In conclusion, this data supports the hypothesis that the PRRSV succeeds to establish and replicate in porcine cells early post-infection, in part, by inducing Th3 regulatory cells as a mechanism of modulating the porcine immune system.

  19. The South Karelia Air Pollution Study. The effects of malodorous sulfur compounds from pulp mills on respiratory and other symptoms

    SciTech Connect (OSTI)

    Jaakkola, J.J.; Vilkka, V.; Marttila, O.; Jaeppinen, P.H.; Haahtela, T. (South Karelia Allergy and Environment Institute, Espoo (Finland))

    1990-12-01T23:59:59.000Z

    The paper mills in South Karelia, the southeast part of Finland, are responsible for releasing a substantial amount of malodorous sulfur compounds such as hydrogen sulfide (H2S), methyl mercaptan (CH3SH), and methyl sulfides ((CH3)2S and (CH3)2S2), into ambient air. In the most polluted residential area the annual mean concentrations of hydrogen sulfide and methyl mercaptan are estimated to be 8 and 2 to 5 micrograms/m3 and the highest daily average concentration 100 and 50 micrograms/m3. The annual mean and highest daily concentrations of sulfur dioxide (SO2) are very low. We studied the effects of malodorous sulfur compounds on eye, nasal and respiratory symptoms, and headache in adults. A cross-sectional self-administered questionnaire was distributed in February 1987 and responded to by 488 adults living in a severely (n = 198), a moderately (n = 204), and a nonpolluted community (n = 86). This included questions about occurrence of the symptoms of interest during the previous 4 wk and 12 months and individual, behavioral, and other environmental determinants of the symptoms. The response rate was 83%. The odds ratios (OR) for symptoms experienced often or constantly in severely versus nonpolluted and moderately versus nonpolluted communities were estimated in logistic regression analysis controlling potential confounders. The odds ratios for eye (moderate exposure OR 11.70, Cl95% 2.33 to 58.65; severe exposure OR 11.78, Cl95% 2.35 to 59.09) and nasal symptoms (OR 2.01, Cl95% 0.97 to 4.15; OR 2.19, Cl95% 1.06 to 4.55) and cough (OR 1.89, Cl95% 0.61 to 5.86; OR 3.06, Cl95% 1.02 to 9.29) during the previous 12 months were increased, with a dose-response pattern.

  20. Postdoctoral Research Awards Annual Research Meeting: Jun Lu...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Jun Lu Postdoctoral Research Awards Annual Research Meeting: Jun Lu Poster Presentation at 2012 EERE Annual Research Meeting, Postdoctoral Research Awards, from the U.S. Department...

  1. Postdoctoral Research Awards Annual Research Meeting: Jared Clark...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Jared Clark Postdoctoral Research Awards Annual Research Meeting: Jared Clark Poster Presentation at the 2012 EERE Annual Research Meeting, Postdoctoral Research Awards, from the...

  2. Postdoctoral Research Awards Annual Research Meeting: Sarah Hobdey...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Sarah Hobdey Postdoctoral Research Awards Annual Research Meeting: Sarah Hobdey Poster Presentation at 2012 EERE Annual Research Meeting, Postdoctoral Research Awards, from the...

  3. Postdoctoral Research Awards Annual Research Meeting: Neil Dasgupta...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Neil Dasgupta Postdoctoral Research Awards Annual Research Meeting: Neil Dasgupta Poster Presentation at 2012 EERE Annual Research Meeting, Postdoctoral Research Awards, from the...

  4. Postdoctoral Research Awards Annual Research Meeting: David Lampert...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    David Lampert Postdoctoral Research Awards Annual Research Meeting: David Lampert Poster Presentation at 2012 EERE Annual Research Meeting, Postdoctoral Research Awards, from the...

  5. Postdoctoral Research Awards Annual Research Meeting: Brian Larsen...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Brian Larsen Postdoctoral Research Awards Annual Research Meeting: Brian Larsen Poster Presentation at 2012 EERE Annual Research Meeting, Postdoctoral Research Awards, from the...

  6. Animal Testing Medical Research

    E-Print Network [OSTI]

    Bech, Claus

    Arondsen Marit Gystřl #12;ZO-8091 Forsřksdyrlćre Animal experiments in medical research NTNU ­ Norges ..................................................................................................................................................... 14 #12;ZO-8091 Forsřksdyrlćre Animal experiments in medical research NTNU ­ Norges Teknisk have come from animal research. Animal research is defined as the use of non-human animals

  7. Jahresbericht der Research Academy

    E-Print Network [OSTI]

    Schüler, Axel

    Jahresbericht der Research Academy Leipzig 2008 #12;Inhalt Die Research Academy Leipzig 3 Vorwort Research Academy Leipzig im Aufwind 3 Die Arbeit der RAL-Doktorandenvertretung 2008 4 Fächerübergreifendes Qualifikationsprogramm Die Veranstaltungen der Research Academy Leipzig 2008 5 Seminar ,,Junge Wissenschaft und Praxis" 6

  8. Microsoft External Research Backgrounder

    E-Print Network [OSTI]

    Narasayya, Vivek

    are undeniable. M icrosoft Research believes that collaboration between the public and private sectors, combined with the power of computing, can help researchers as they work to solve the most urgent challenges in medicine, Building the Future of Technology Microsoft External Research Backgrounder #12;The team promotes research

  9. Research Roadmap Presentation

    E-Print Network [OSTI]

    Sloman, Aaron

    Research Roadmap Presentation: euCognition Meeting, Munich 12 Jan 2007 http://www.eucognition.org/six_monthly_meeting_2.htm What's a Research Roadmap For? Why do we need one? How can we produce one? Aaron Sloman ( http.cs.bham.ac.uk/research/projects/cosy/papers/#pr0701 See also the euCognition Research Roadmap project: http://www.eucognition.org/wiki/index.php?title=Research_Roadmap

  10. 2012 MITOCHONDRIA AND CHLOROPLASTS GORDON RESEARCH CONFERENCE & GORDON RESEARCH SEMINAR, JULY 29 - AUGUST 3, 2012

    SciTech Connect (OSTI)

    Barkan, Alice

    2012-08-03T23:59:59.000Z

    The 2012 Gordon Research Conference on Mitochondria and Chloroplasts will assemble an international group of scientists investigating fundamental properties of these organelles, and their integration into broader physiological processes. The conference will emphasize the many commonalities between mitochondria and chloroplasts: their evolution from bacterial endosymbionts, their genomes and gene expression systems, their energy transducing membranes whose proteins derive from both nuclear and organellar genes, the challenge of maintaining organelle integrity in the presence of the reactive oxygen species that are generated during energy transduction, their incorporation into organismal signaling pathways, and more. The conference will bring together investigators working in animal, plant, fungal and protozoan systems who specialize in cell biology, genetics, biochemistry, physiology, proteomics, genomics, and structural biology. As such, this conference will provide a unique forum that engenders cross-disciplinary discussions concerning the biogenesis, dynamics, and regulation of these key cellular structures. By fostering interactions among mammalian, fungal and plant organellar biologists, this conference also provides a conduit for the transmission of mechanistic insights obtained in model organisms to applications in medicine and agriculture. The 2012 conference will highlight areas that are moving rapidly and emerging themes. These include new insights into the ultrastructure and organization of the energy transducing membranes, the coupling of organellar gene expression with the assembly of photosynthetic and respiratory complexes, the regulatory networks that couple organelle biogenesis with developmental and physiological signals, the signaling events through which organellar physiology influences nuclear gene expression, and the roles of organelles in disease and development.

  11. Participant Benefit Booklet July 1, 2011 -June 30, 2012

    E-Print Network [OSTI]

    New Mexico, University of

    /or Substance Abuse 48 Physician Services 49 Preventive Care 50 Skilled Nursing Facility 53 Smoking Cessation 53 by Lovelace Insurance Company #12;CUSTOMER CARE CENTER ­ 505.727.LOVE (5683) OR 800.808-7363 LOVELACE WORKS 19 UNM Provider Directory 19 Network Providers Outside of New Mexico 20 Lovelace Customer Care

  12. Research Teams - Combustion Energy Frontier Research Center

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Scienceand Requirements RecentlyElectronic Public Reading Room ElectronicResearchResearchResearch

  13. Senior Research Associate Taconite Industry Minerals Research Endowed Chair

    E-Print Network [OSTI]

    Netoff, Theoden

    Senior Research Associate Taconite Industry Minerals Research Endowed Chair Job Requisition 170892 Coleraine Minerals Research Laboratory Natural Resources Research Institute University of Minnesota Duluth (www.nrri.umn.edu) Position Description The Taconite Industry Minerals Research Endowed Chair

  14. A "blind" study of the power spectra analysis of respiratory sounds at the trachea of a sample of pulmonary insufficiency patients and normal subjects

    E-Print Network [OSTI]

    Wolf, Brenda Ann

    1985-01-01T23:59:59.000Z

    the condition of the lungs. The slow progress is due to: (1) a variety of human factor problems, (2) the limitations of the instrumentation, (3) the lack of total understanding of the mechanism of production of respiratory sounds, and (4) the lack... was a "blind s'tudy The equipment used in the analysis of the magnetic tapes consisted of the following components: 1. Ampex 2200 PM analog tape recorder 2, Datum Time Code Generator/Reader Model 9300 3. 20 Hz, 1800 Hz low pass filters 4. 100 Hz...

  15. Gasification Research BIOENERGY PROGRAM

    E-Print Network [OSTI]

    Gasification Research BIOENERGY PROGRAM Description Researchers inthe@tamu.edu Skid-mounted gasifier: 1.8 tons-per-day pilot unit Gasification of cotton gin trash The new Texas A

  16. Photocatalysis Currently, the research

    E-Print Network [OSTI]

    Vollmer, Heribert

    Photocatalysis Currently, the research activit in the area ofies Photocatalysis focus on the topics Photocatalysis and Prof. Dr. Detlef Bahnemann Nanotechnology Research Topics Bioprocess Engineering Bioprocess Modeling and Control Photocatalysis and Nanotechnology Institute of Technical Chemistry Contact Person

  17. University Research Summaries

    Broader source: Energy.gov [DOE]

    The Idaho National Laboratory published the U.S. Department of Energy's (DOE) Geothermal Technologies Office 2001 University Research Summaries. 

  18. Xu Zhang's Homepage - Research

    E-Print Network [OSTI]

    Research Interests. Numerical Methods for Partial Differential Equations; Finite Element and Discontinuous Galerkin Methods; Immersed Finite Element Methods

  19. Graduate Research Scholarships

    E-Print Network [OSTI]

    and Engineering Research Council of Canada Master's scholarships (17,5K, one year, non- renewable) Doctoral Research of Canada Master's scholarships (17,5K for one year, non- renewable) Doctoral scholarships (30k scholarships (20K per year, first nine semesters) Social Sciences and Humanities Research Council of Canada

  20. RESEARCH BUILDING AT NORTHWESTERN

    E-Print Network [OSTI]

    Engman, David M.

    BIOMEDICAL RESEARCH BUILDING AT NORTHWESTERN MEDICINE #12;"Our new Biomedical Research Building-intensive medical schools. Perkins+Will has designed a building that will be superbly functional and have great a magnificent 12-story Biomedical Research Building to address this priority. The new 600,000 square foot

  1. INTERNATIONAL PACIFIC RESEARCH CENTER

    E-Print Network [OSTI]

    Wang, Yuqing

    INTERNATIONAL PACIFIC RESEARCH CENTER Annual Report April 2006 ­ March 2007 School of Ocean Research Center 1 2 The Year's Highlights 3 Research Accomplishments Indo-Pacific Ocean Climate 4 Regional-Ocean Ocean Climate: To understand climate variations in the Pacific and Indian oceans on inter- annual

  2. Natural Sciences Research Outlook

    E-Print Network [OSTI]

    Sciences (July 2009), including: UK Research Councils: Biotechnology and Biological· Sciences ResearchEpARTmENT oF phySICS 14 CENTRE FoR ENVIRoNmENTAL poLICy 15 RESEARCh INSTITUTES ANd CENTRES 16 ENERGy ANd ENVIRo

  3. Researchers Edition 2014

    E-Print Network [OSTI]

    Genčve, Université de

    on the thematic priorities "Translational biomedical research and medical techno- logy" and "Renewable Energy of Geneva (UNIGE). UNIGE's researchers annually obtain more than 130 million Swiss Francs, earmarked for research, from sources such as: the Swiss National Science Foundation (SNSF), the European Union (EU

  4. BRAZIL RESEARCH INITIATIVES

    E-Print Network [OSTI]

    Liu, Taosheng

    BRAZIL RESEARCH INITIATIVES Michigan State University (MSU) identifies Brazil as a global priority and challenges become increasingly part of the U.S.-Brazil agenda, MSU desires partnerships aimed at producing in the U.S. and one in Brazil, to share research strategies and explore joint projects in several research

  5. Reservoir Characterization Research Laboratory

    E-Print Network [OSTI]

    Texas at Austin, University of

    Reservoir Characterization Research Laboratory for Carbonate Studies Executive Summary for 2014 Outcrop and Subsurface Characterization of Carbonate Reservoirs for Improved Recovery of Remaining/Al 0.00 0.02 0.04 Eagle Ford Fm #12;#12; Reservoir Characterization Research Laboratory Research Plans

  6. Louisiana Transportation Research Center

    E-Print Network [OSTI]

    Harms, Kyle E.

    Louisiana Transportation Research Center LTRC www.ltrc.lsu.edu 2012-13 ANNUALREPORT #12;The Louisiana Transportation Research Center (LTRC) is a research, technology transfer, and training center administered jointly by the Louisiana Department of Transportation and Development (DOTD) and Louisiana State

  7. HR Strategy for Researchers

    E-Print Network [OSTI]

    Fabra, established in 1990, is a research-oriented, public higher education institution. UPF has of international researchers that it recruits. Consistent with this commitment to internationalization, UPF signed of Researchers (hereafter, the Charter and Code) in 2010. UPF belongs to the 3rd Cohort of the Human Resources

  8. Research Councils UK Engaging Young

    E-Print Network [OSTI]

    Rambaut, Andrew

    Research Councils UK Engaging Young People with Cutting Edge Research: a guide for researchers to the feel-good factor researchers can have a hand in inspiring the next generation of researchers, to secure

  9. Epidemiological-environmental study of diesel bus garage workers: acute effects of NO/sub 2/ and respirable particulate on the respiratory system

    SciTech Connect (OSTI)

    Gamble, J.; Jones, W.; Minshall, S.

    1987-02-01T23:59:59.000Z

    Personal samples of nitrogen dioxide (NO/sub 2/) and respirable particulate (RP) were collected over the shift on 232 workers in four diesel bus garages. Response was assessed by an acute respiratory questionnaire and before and after shift spirometry. Measures of exposure to NO/sub 2/ and RP were associated with work-related symptoms of cough; itching, burning, or watering eyes; difficult or labored breathing; chest tightness; and wheeze. The prevalence of burning eyes, headaches, difficult or labored breathing, nausea, and wheeze experienced at work were higher in the diesel bus garage workers than in a comparison population of battery workers, while the prevalence of headaches was reduced. Mean reductions in forced vital capacity (FVC), forced expiratory volume in 1 sec (FEV1), peak flow, and flows at 50 and 75% of FVC were not obviously different from zero. There was no detectable association of exposure to NO/sub 2/ or respirable particulate and acute reductions in pulmonary function. Workers who often had respiratory work-related symptoms generally had a slightly greater mean acute reduction in FEV1 and FEF50 than did those who did not have these symptoms, but these differences were not statistically significant.

  10. Supporting Your Research at Ohio State Office of Research

    E-Print Network [OSTI]

    ­ Randy Moses · Food, Agricultural, & Environmental Sciences ­ Steve Slack · Law ­ Donald Tobin · Medicine at Ohio State Office of Research Research Support Resources Visit the Office of Research web site

  11. Sandia National Laboratories: Research: Research Foundations

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclearHomeland and NuclearReportMaterials ScienceResearch

  12. Research Form | Photosynthetic Antenna Research Center

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What's PossibleRadiation Protection Technical s o Freiberge s 3 % A PB 2 7 7Research Form Research Form

  13. RESEARCH PERSONNEL AND ENGINEERING STAFF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Physicist Dennis Utley, Research Associate (25%) Computer Systems Staff Robert Burch, Jr., Research Associate John C. Hagel, Assoc. Research Scientist (50%) Maxim...

  14. Sponsored Research | Argonne National Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Research and Development Agreement A Cooperative Research and Development Agreement (CRADA) defines and governs an Argonne-industry collaborative research relationship with the...

  15. 18 Research Activities 2012 Research Frontiers

    E-Print Network [OSTI]

    Takada, Shoji

    the changing process of people's lives under globalization and examine its links with the current socio that understanding India will shed light upon a path towards a diversity-enhancing globalization. INDAS is keen undertakes research on Islamic law and economics, including the recently developed Islamic economy

  16. 2009 SEAri Annual Research Summit Research Topic

    E-Print Network [OSTI]

    de Weck, Olivier L.

    Massachusetts Institute of Technology 6 Tradespace Exploration Paradigm: Avoiding Point Designs Cost Utility, 2009 Cambridge, MA Massachusetts Institute of Technology #12;seari.mit.edu SEAri Annual Research Summit © 2009 Massachusetts Institute of Technology 2 Tradespace Exploration (TSE) · Model-based, high

  17. Robotics research projects report

    SciTech Connect (OSTI)

    Hsia, T.C. (ed.)

    1983-06-01T23:59:59.000Z

    The research results of the Robotics Research Laboratory are summarized. Areas of research include robotic control, a stand-alone vision system for industrial robots, and sensors other than vision that would be useful for image ranging, including ultrasonic and infra-red devices. One particular project involves RHINO, a 6-axis robotic arm that can be manipulated by serial transmission of ASCII command strings to its interfaced controller. (LEW)

  18. Indian Agricultural Statistics Research Institute (Indian Council of Agricultural Research)

    E-Print Network [OSTI]

    Rodriguez, Carlos

    #12;Indian Agricultural Statistics Research Institute (Indian Council of Agricultural Research, Indian Agricultural Statistics Research Institute (ICAR), Library Avenue, Pusa, New Delhi-110012 : July 2011 All Rights Reserved 2011, Indian Agricultural Statistics Research Institute (ICAR), New Delhi

  19. Reservoir CharacterizationReservoir Characterization Research LaboratoryResearch Laboratory

    E-Print Network [OSTI]

    Texas at Austin, University of

    Reservoir CharacterizationReservoir Characterization Research LaboratoryResearch Laboratory at Austin Austin, Texas 78713Austin, Texas 78713--89248924 #12;Reservoir Characterization Research Laboratory for Carbonate Studies Research Plans for 2012 Outcrop and Subsurface Characterization of Carbonate

  20. Advanced Scientific Computing Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    research along with supporting narratives, illustrated by specific science-based case studies. Findings from the review will guide NERSC procurements and service offerings...

  1. ORISE: Research and Evaluation

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    (ORISE) assists government agencies and organizations create effective health communication programs that are built on solid research and evaluation. This information helps...

  2. research 1..8

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of the Accounts of Chemical Research virtual special issue "2D Nanomaterials beyond 3 Graphene". 4 Michael Naguib and Yury Gogotsi* , 5 Materials Science and Technology...

  3. Intelligence Research Specialist

    Broader source: Energy.gov [DOE]

    A successful candidate in this position will serve as an Intelligence Research Specialist for the Foreign Nuclear Programs Division (FNPD), Directorate of Intelligence Analysis (IN10), Office of...

  4. National Laboratory Photovoltaics Research

    Broader source: Energy.gov [DOE]

    DOE supports photovoltaic (PV) research and development and facilities at its national laboratories to accelerate progress toward achieving the SunShot Initiative's technological and economic...

  5. CFN | Research Highlights Archive

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Center for Functional Nanomaterials Research Highlights Archives lithium ion battery cell Peering into How Rechargeable Lithium Ion Batteries Function Wednesday, March 18, 2015...

  6. Research | Argonne National Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    our dependence on imported energy and to enhance our national security. In addition, Argonne provides many ways for researchers from academia, industry and other government...

  7. Research | Nicholas Miller

    E-Print Network [OSTI]

    2015-03-19T23:59:59.000Z

    Mar 19, 2015 ... I am currently a graduate student at Purdue University advised by Ben McReynolds. My research interests lie in the fields of arithmetic, ...

  8. EERE Postdoctoral Research Awards Letter of Support from Research...

    Broader source: Energy.gov (indexed) [DOE]

    letterofsupport2015.pdf More Documents & Publications EERE Postdoctoral Research Award Application Components EERE Postdoctoral Research Awards Application Checklist EERE...

  9. Research Integrity A Guide for Research Postgraduate Students

    E-Print Network [OSTI]

    Tam, Vincent W. L.

    that all members of the HKU research family are well versed in research integrity. This booklet is intendedResearch Integrity A Guide for Research Postgraduate Students at The University of Hong Kong A publication of the Graduate School #12;Research Integrity: A Guide for Research Postgraduate Students

  10. Intracellular shunting of O{sub 2}{sup ?} contributes to charge compensation and preservation of neutrophil respiratory burst in the absence of voltage-gated proton channel activity

    SciTech Connect (OSTI)

    Decleva, Eva [Department of Life Sciences, University of Trieste, Trieste (Italy); Menegazzi, Renzo, E-mail: menegazz@units.it [Department of Life Sciences, University of Trieste, Trieste (Italy); Fasolo, Alba [Department of Life Sciences, University of Trieste, Trieste (Italy); Defendi, Federica [Université Joseph Fourier, GREPI/AGIM CNRS FRE 3405, Grenoble (France); Sebastianutto, Michele; Dri, Pietro [Department of Life Sciences, University of Trieste, Trieste (Italy)

    2013-07-15T23:59:59.000Z

    Proton efflux via voltage-gated proton channels (Hv1) is considered to mediate the charge compensation necessary to preserve NADPH oxidase activity during the respiratory burst. Using the Hv1 inhibitor Zn{sup 2+}, we found that the PMA-induced respiratory burst of human neutrophils is inhibited when assessed as extracellular production of O{sub 2}{sup ?} and H{sub 2}O{sub 2}, in accordance with literature studies, but, surprisingly, unaffected when measured as oxygen consumption or total (extracellular plus intracellular) H{sub 2}O{sub 2} production. Furthermore, we show that inhibiting Hv1 with Zn{sup 2+} results in an increased production of intracellular ROS. Similar results, i.e. decreased extracellular and increased intracellular ROS production, were obtained using a human granulocyte-like cell line with severely impaired Hv1 expression. Acidic extracellular pH, which dampens proton efflux, also augmented intracellular production of H{sub 2}O{sub 2}. Zinc caused an increase in the rate but not in the extent of depolarization and cytosolic acidification indicating that mechanisms other than proton efflux take part in charge compensation. Our results suggest a hitherto unpredicted mechanism of charge compensation whereby, in the absence of proton efflux, part of O{sub 2}{sup ?} generated within gp91{sup phox} in the plasma membrane is shunted intracellularly down electrochemical gradient to dampen excessive depolarization. This would preserve NADPH oxidase activity under conditions such as the inflammatory exudate in which the acidic pH hinders charge compensation by proton efflux. Highlights: • Neutrophils’ respiratory burst is not inhibited by the H{sup +} channel inhibitor Zn{sup 2+}. • Intracellular production of O{sub 2}{sup ?} and H{sub 2}O{sub 2} is increased in the presence of Zn{sup 2+}. • Intracellular H{sub 2}O{sub 2} production is increased in H{sup +} channels knock-down cells. • Zn{sup 2+} increases the rate but not the extent of depolarization and pH{sub i} decrease. • Intracellular shunting of O{sub 2}{sup ?} contributes to charge compensation in neutrophils.

  11. WORK PROGRAMME 2010 RESEARCH POTENTIAL

    E-Print Network [OSTI]

    Milano-Bicocca, Universitŕ

    the research potential of research entities established in the Western Balkan Countries' regions equivalent and developing the research potential of research entities established in the Western Balkan Countries' regions

  12. Environmental Sciences 2007 Research Evaluation,

    E-Print Network [OSTI]

    Utrecht, Universiteit

    Environmental Sciences 2007 Research Evaluation, including SENSE Research School December 2007 #12; QANU/ResearchEvaluationEnvironmentalSciences007 Quality,byphotocopy- ingorbyanyothermeanswiththepermissionofQANUifthesourceismentioned. #12;3QANU/ResearchEvaluationEnvironmentalSciences007 Table of contents

  13. Arnold Schwarzenegger RESEARCH ON MANUFACTURING

    E-Print Network [OSTI]

    For: California Energy Commission Public Interest Energy Research Program Prepared By: University Hicks, Principal Investigator Yan Sun, Research Assistant David Tobin, Research Assistant Dick Cheng: California Energy Commission Public Interest Energy Research (PIER) Program Energy Innovations Small Grants

  14. Research Statement Noah Finkelstein

    E-Print Network [OSTI]

    Finkelstein, Noah

    focuses on the role of context, and in particular three levels of context critical to students' learningResearch Statement Noah Finkelstein Physics Education Research and Contexts of Student Learning My of sustainable and scaleable reforms? Building on the established foundations of PER that have focused on student

  15. Market Research Company Description

    E-Print Network [OSTI]

    Dahl, David B.

    development - Market research for enterprise and education adoption - Plan and execute a company-wide pingMarket Research Company Description: A company focused on developing web-based graphical and future products and then develop the necessary strategies and collateral to stay on the bleeding edge

  16. Science & Research Agriculture & Food

    E-Print Network [OSTI]

    Science & Research Agriculture & Food Climate & Environment Consumers EU Priorities 2020 EU Treaty for nuclear fusion project ITER | EurActiv http://www.euractiv.com/en/science/funding-crisis-for-nuclear for nuclear fusion project ITER A multi-billion euro international research project has run into deep

  17. Announcement Dissertation Research Award

    E-Print Network [OSTI]

    Slatton, Clint

    Announcement Dissertation Research Award Applications are now available for the fall 2009 Dissertation Research Award. The program is open to doctoral students in a transportation-related discipline area who have been admitted to Candidacy by the Graduate School with a dissertation proposal approved

  18. Sarah Widder Research Engineer

    E-Print Network [OSTI]

    -6396 sarah.widder@pnnl.gov Visit us at: http://labhomes.pnnl.gov Demonstrating tomorrow's efficient and smart, and circuit level energy consumption. All data are collected and stored in the data acquisition system. PNNL measured. Lab Homes is a research platform for PNNL and its research partners to achieve highly energy

  19. International Pacific Research Center

    E-Print Network [OSTI]

    Wang, Yuqing

    International Pacific Research Center APRIL 2007­MARCH 2008 REPORT School of Ocean and Earth Center i Foreword ii iv Indo-Pacific Ocean Climate 1 Regional-Ocean Influences 13 Asian by the following broad research themes and goals of the IPRC Science Plan. Indo-Pacific Ocean Climate

  20. Research Grants & Contracts (RGC)

    E-Print Network [OSTI]

    Chapman, Michael S.

    , need to change Agreement/Contract Characteristics include: - A negotiation phase to determine Material Transfer Agreements Research Agreements/Contracts Research Agreement Amendments Subcontracts such as change in scope of the project, change of key personnel, etc. Grant: A formal application process related

  1. Soil Testing and Research

    E-Print Network [OSTI]

    Ciocan-Fontanine, Ionut

    Soil Testing and Research Analytical Laboratory Copyright © 2014 University of Minnesota Soil Testing and Research Analytical Laboratory Department of Soil, Water and Climate College of Food payable to the University of Minnesota We also accept the following credit cards: Soil Testing

  2. RESEARCH UPDATE Ecology Division

    E-Print Network [OSTI]

    1 RESEARCH UPDATE Ecology Division Biotype has changed its name to Ecotype! Following the re-organisation of Forest Research into five science Divisions and three Support Divisions, the former Woodland Ecology Branches to form the new Ecology Division. We decided to give the divisional newsletter a new name (and

  3. Photoionization-photoelectron research

    SciTech Connect (OSTI)

    Berkowitz, J.; Ruscic, B. [Argonne National Laboratory, IL (United States)

    1993-12-01T23:59:59.000Z

    The photoionization research program is aimed at understanding the basic processes of interaction of vacuum ultraviolet (VUV) light with atoms and molecules. This research provides valuable information on both thermochemistry and dynamics. Recent studies include atoms, clusters, hydrides, sulfides and an important fluoride.

  4. Research Statement Sudipta Kundu

    E-Print Network [OSTI]

    Simunic, Tajana

    Research Statement Sudipta Kundu Programming errors or bugs are omnipresent in critical areas are among several of the horror stories caused by software or hardware bugs. My research focuses to economic loss as well as loss of human lives. The Pentium FDIV bug, ARIANE failure, or Therac-25 accident

  5. Powertrain & Vehicle Research Centre

    E-Print Network [OSTI]

    Burton, Geoffrey R.

    Powertrain & Vehicle Research Centre Low Carbon Powertrain Development S. Akehurst, EPSRC Advanced Research Fellow A vehicles powertrain is a complex combination of interacting sub-systems which include complexity ·More efficient Vehicles, quicker to market, reduced cost to consumer The Optimisation Task

  6. ASHRAE Research PROGRAM OVERVIEW

    E-Print Network [OSTI]

    Oak Ridge National Laboratory

    of appliances , such as heat pump water heaters 2. Our equipment rating methods are (at best) obsolete's Strategic Plan for Research · Research and Objectives related to Heat Pumps · GSHP System at ASHRAE HQ: · Indoor Environmental Quality (IEQ) · Sustainability: Solar, Geothermal, Heat Pumps, Fuel Cells, CHP, etc

  7. Honorary Edition Potato Research

    E-Print Network [OSTI]

    Douches, David S.

    2002 Volume 34 Honorary Edition Michigan Potato Research Report Only a few persons have the wisdom single person has done so much for the potato industry. His vision and attention to detail have helped gratitude once more. I am pleased to dedicate the 2002 Michigan Potato Industry Commission Research Report

  8. NREL: Wind Research - Advanced Research Turbines

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What's Possible for Renewable Energy: GridTruck Platooning Testing Photo ofResearch Staff

  9. Sandia National Labs: PCNSC: Research: Research Briefs

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What's PossibleRadiationImplementingnpitcheResearch Briefs The annually published Physical, Chemical, and

  10. Estimates of the absorbed fraction of energy for various electron source and target regions in the upper respiratory tract

    E-Print Network [OSTI]

    Calvo, Sebastian

    1994-01-01T23:59:59.000Z

    airway surfaces, exhibiting localized concentrations at carinal ridge. Further, Hofmann et al. (1991), while studying radon progeny, found that the combined effect of enhanced deposition and reduced clearance at bronchial bifurcations leads... to increased radon progeny doses within branching sites compared with uniformly distributed activity within a given airway generation. Thus, research suggests that particular attention should be paid to the carina when studying deposition of radioactive...

  11. CFD modeling and image analysis of exhaled aerosols due to a growing bronchial tumor: Towards non-invasive diagnosis and treatment of respiratory obstructive diseases

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Xi, Jinxiang; Kim, JongWon; Si, Xiuhua A.; Corley, Richard A.; Kabilan, Senthil; Wang, Shengyu

    2015-01-01T23:59:59.000Z

    Diagnosis and prognosis of tumorigenesis are generally performed with CT, PET, or biopsy. Such methods are accurate, but have the limitations of high cost and posing additional health risks to patients. In this study, we introduce an alternative computer aided diagnostic tool that can locate malignant sites caused by tumorigenesis in a non-invasive and low-cost way. Our hypothesis is that exhaled aerosol distribution is unique to lung structure and is sensitive to airway structure variations. With appropriate approaches, it is possible to locate the disease site, determine the disease severity, and subsequently formulate a targeted drug delivery plan to treatmore »the disease. This study numerically evaluated the feasibility of the proposed breath test in an image-based lung model with varying pathological stages of a bronchial squamous tumor. Large eddy simulations and a Lagrangian tracking approach were used to model respiratory airflows and aerosol dynamics. Respirations of tracer aerosols of 1 ?m at a flow rate of 20 L/min were simulated, with the distributions of exhaled aerosols recorded on a filter at the mouth exit. Aerosol patterns were quantified with multiple analytical techniques such as concentration disparity, spatial scanning and fractal analysis. We demonstrated that a growing bronchial tumor induced notable variations in both the airflow and exhaled aerosol distribution. These variations became more apparent with increasing tumor severity. The exhaled aerosols exhibited distinctive pattern parameters such as spatial probability, fractal dimension, and multifractal spectrum. Results of this study show that morphometric measures of the exhaled aerosol pattern can be used to detect and monitor the pathological states of respiratory diseases in the upper airway. The proposed breath test also has the potential to locate the site of the disease, which is critical in developing a personalized, site-specific drug delivery protocol.« less

  12. NREL Research Participant Program

    SciTech Connect (OSTI)

    Christensen, Dana

    2011-01-01T23:59:59.000Z

    The mission of the National Renewable Energy Laboratory (NREL) is to lead the nation toward a clean energy future. To achieve this mission, NREL must gather and engage the finest talents for our energy programs. That's one reason NREL provides resources and opportunities for innovative research and thought leadership through our Research Participant Programs. Whether you choose to participate in energy efficiency and renewable energy research, our Energy Analysis or NREL's commercialization and deployment disciplines, you will find unique and impactful opportunities across the lab.

  13. Jointly Sponsored Research Program Energy Related Research

    SciTech Connect (OSTI)

    Western Research Institute

    2009-03-31T23:59:59.000Z

    Cooperative Agreement, DE-FC26-98FT40323, Jointly Sponsored Research (JSR) Program at Western Research Institute (WRI) began in 1998. Over the course of the Program, a total of seventy-seven tasks were proposed utilizing a total of $23,202,579 in USDOE funds. Against this funding, cosponsors committed $26,557,649 in private funds to produce a program valued at $49,760,228. The goal of the Jointly Sponsored Research Program was to develop or assist in the development of innovative technology solutions that will: (1) Increase the production of United States energy resources - coal, natural gas, oil, and renewable energy resources; (2) Enhance the competitiveness of United States energy technologies in international markets and assist in technology transfer; (3) Reduce the nation's dependence on foreign energy supplies and strengthen both the United States and regional economies; and (4) Minimize environmental impacts of energy production and utilization. Under the JSR Program, energy-related tasks emphasized enhanced oil recovery, heavy oil upgrading and characterization, coal beneficiation and upgrading, coal combustion systems development including oxy-combustion, emissions monitoring and abatement, coal gasification technologies including gas clean-up and conditioning, hydrogen and liquid fuels production, coal-bed methane recovery, and the development of technologies for the utilization of renewable energy resources. Environmental-related activities emphasized cleaning contaminated soils and waters, processing of oily wastes, mitigating acid mine drainage, and demonstrating uses for solid waste from clean coal technologies, and other advanced coal-based systems. Technology enhancement activities included resource characterization studies, development of improved methods, monitors and sensors. In general the goals of the tasks proposed were to enhance competitiveness of U.S. technology, increase production of domestic resources, and reduce environmental impacts associated with energy production and utilization. This report summarizes the accomplishments of the JSR Program.

  14. Oil and Gas Research| GE Global Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclear Astrophysics One ofSpeeding accessOffice ofOfficesOil &

  15. Research - Combustion Energy Frontier Research Center

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclear Press Releases 2014References by Websitehome /Request a

  16. Sandia National Laboratories: Research: Research Foundations: Engineering

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclearHomeland and NuclearReportMaterialsScience

  17. Sandia National Laboratories: Research: Research Foundations: Geoscience

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclearHomeland and NuclearReportMaterialsScienceGeoscience

  18. Sandia National Laboratories: Research: Research Foundations: Nanodevices

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclearHomeland and

  19. Sandia National Laboratories: Research: Research Foundations: Radiation

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclearHomeland andEffects and High Energy Density Science

  20. NREL: Concentrating Solar Power Research - Research Staff

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Saleshttp://www.fnal.gov/directorate/nalcal/nalcal02_07_05_files/nalcal.gifNREL NRELChemical andWhat IsThermalReceiverResearch

  1. Research Affiliate Program | Photosynthetic Antenna Research Center

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Scienceand Requirements Recently ApprovedReliabilityPrincipal InvestigatorsResearch Affiliate

  2. Research Affiliates | Photosynthetic Antenna Research Center

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Scienceand Requirements Recently ApprovedReliabilityPrincipal InvestigatorsResearch

  3. Research Highlights Sorted by Research Area

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Scienceand Requirements Recently ApprovedReliabilityPrincipalResearchMaking Sense of

  4. NREL: Water Power Research - Research Staff

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What's Possible for Renewable Energy: GridTruck Platooning Testing Photo ofResearch Staff Below is a

  5. NREL: Wind Research - Research Staff Biographies

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What's Possible for Renewable Energy: GridTruck Platooning Testing Photofrom U.S.6 DecemberWindResearch

  6. Research Affiliates | Photosynthetic Antenna Research Center

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What's PossibleRadiation Protection Technical s o Freiberge s 3 % A PB 2 7 7 2Research &Affiliates

  7. Agricultural Research Service (ARS) Research Participation Program -

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041cloth DocumentationProducts (VAP) VAP7-0973Managed by ORAU Agricultural Research Service (ARS)

  8. Photovoltaic Research Facilities

    Broader source: Energy.gov [DOE]

    The U.S. Department of Energy (DOE) funds photovoltaic (PV) research and development (R&D) at its national laboratory facilities located throughout the country. To encourage further innovation,...

  9. Operation Research Analyst

    Broader source: Energy.gov [DOE]

    The incumbent in this position will serve as an Operation Research Analyst in the Market Analysis and Pricing organization of Power Services. This organization is responsible for performing market...

  10. Evaluation of Physics Research

    E-Print Network [OSTI]

    Franssen, Michael

    1 Evaluation of Physics Research Eindhoven University of Technology 1996-2003 April 2006 #12;2 3........................................................................................................................................................... 11 Individual Programme Evaluation Eindhoven University of Technology (RU) in September 2004 ­ and Technische Universiteit Eindhoven (TUE) decided to have their physics

  11. Research Experience for Undergraduates

    E-Print Network [OSTI]

    Tennessee, University of

    · smart grid technology · power markets · electric vehicles · energy harvesting program details · Stipend, including power systems and power electronics as they relate to the national power grid. research areas · power systems · power electronics · data visualization · cyber security · electronic power conversion

  12. Atmospheric Research at BNL

    ScienceCinema (OSTI)

    Peter Daum

    2010-01-08T23:59:59.000Z

    Brookhaven researcher Peter Daum discusses an international field experiment designed to make observations of critical components of the climate system of the southeastern Pacific. Because elements of this system are poorly understood and poorly represent

  13. Research Article Signaling Threat

    E-Print Network [OSTI]

    Gross, James J.

    Research Article Signaling Threat How Situational Cues Affect Women in Math, Science and organization,canmake potentialtargetsvulnerabletosocial identity threat.Objective and subjective measuresofidentity threat were collected from male and female math, science, and engineering (MSE) majors who watched

  14. Research Data Management - Documentation

    E-Print Network [OSTI]

    Collins, Anna

    2013-01-01T23:59:59.000Z

    This short (16 slide) presentation "Documentation" explains the need to create documentation using several clear examples of the benefits from good documentation (and what can happen if it is not good), making research reproducible...

  15. Deep Research Submarine

    E-Print Network [OSTI]

    Woertz, Jeff

    2002-02-01T23:59:59.000Z

    The Deep Sea Research Submarine (Figure 1) is a modified VIRGINIA Class Submarine that incorporates a permanently installed Deep Sea Operations Compartment (Figure 2). Table 1 summarizes the characteristics of the Deep ...

  16. Research News November 2014

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Amine Sorbents" and No. 8,834,822 for "Regenerable Immobilized Aminosilane Sorbents for Carbon Dioxide Capture." Contact: McMahan Gray Research news 6 M ultiphase flow is the...

  17. The Computational Sciences. Research

    E-Print Network [OSTI]

    Christensen, Dan

    The Computational Sciences. Research activities range from the theoretical foundations. The teaching mission of the computational sciences includes almost every student in the University for computational hardware and software. The computational sciences are undergoing explosive growth worldwide

  18. GREEN INFRASTRUCTURE Researchers

    E-Print Network [OSTI]

    Delaware, University of

    , environmental studies, history, and engineering. Research programs currently organized in the Center include ...................................................................................................................................1 1.2 Environmental Impacts of Urbanization ............................................... Center for Energy and Environmental Policy University of Delaware Newark, DE 19716-7381 Email: jbbyrne

  19. Research | Argonne National Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    to a number of world-class user facilities that host hundreds of scientists annually. Argonne also leads the Joint Center for Energy Storage Research and plays a key role in...

  20. Research News TEMPLATE

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    is important work that we do, and I am passionate in my belief that NETL's research and development focus on enabling technologies for sustainable fossil fuel utilization is of...

  1. Thin Film Photovoltaics Research

    Broader source: Energy.gov [DOE]

    The U.S. Department of Energy (DOE) supports research and development of four thin-film technologies on the path to achieving cost-competitive solar energy, including:

  2. NPS Research supports Naval

    E-Print Network [OSTI]

    · Management Stanley Arthur Chair of Logistics· RADM George F. Wagner Chair in· Public Management Chair WAYNE E. MEYER INSTITUTE OF SYSTEMS ENGINEERING FY08 Naval Sponsored Program Research and Education: $36

  3. EERE Postdoctoral Research Awards

    Broader source: Energy.gov [DOE]

    The Energy Efficiency and Renewable Energy (EERE) Postdoctoral Research Awards support EERE’s mission in energy efficiency and renewable energy by offering recent Ph.D. recipients the opportunity...

  4. A World of Research REPORT ON RESEARCH 2007

    E-Print Network [OSTI]

    Nagurney, Anna

    A World of Research REPORT ON RESEARCH 2007 #12;REPORT ON RESEARCH 2007 2 TABLE OF CONTENTS Page Health 10 Engaging Student Researchers 12 Connecting with the Commonwealth 15 Impacting the World 18, the nation and the world. The Office of the Vice Provost for Research provides services in support

  5. Fuel Cell Research

    SciTech Connect (OSTI)

    Weber, Peter M. [Brown University] [Brown University

    2014-03-30T23:59:59.000Z

    Executive Summary In conjunction with the Brown Energy Initiative, research Projects selected for the fuel cell research grant were selected on the following criteria: ? They should be fundamental research that has the potential to significantly impact the nation’s energy infrastructure. ? They should be scientifically exciting and sound. ? They should synthesize new materials, lead to greater insights, explore new phenomena, or design new devices or processes that are of relevance to solving the energy problems. ? They involve top-caliper senior scientists with a record of accomplishment, or junior faculty with outstanding promise of achievement. ? They should promise to yield at least preliminary results within the given funding period, which would warrant further research development. ? They should fit into the overall mission of the Brown Energy Initiative, and the investigators should contribute as partners to an intellectually stimulating environment focused on energy science. Based on these criteria, fourteen faculty across three disciplines (Chemistry, Physics and Engineering) and the Charles Stark Draper Laboratory were selected to participate in this effort.1 In total, there were 30 people supported, at some level, on these projects. This report highlights the findings and research outcomes of the participating researchers.

  6. Reservoir Characterization Research Laboratory Research Plans for 2013

    E-Print Network [OSTI]

    Texas at Austin, University of

    and Subsurface Characterization of Carbonate Reservoirs for Improved Recovery of Remaining Hydrocarbons Charles#12; Reservoir Characterization Research Laboratory Research Plans for 2013 Outcrop for heavy oil deposits within the Canadian Grosmont Formation. #12;iii Reservoir Characterization Research

  7. Postdoctoral Research Awards Annual Research Meeting: John Shelton...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Documents & Publications EERE Postdoctoral Research Awards Annual Meeting Posters A History or Geothermal Energy Research and Development in the United States: Drilling 1976-2006...

  8. Research for the South Climate research, equatorial Andes

    E-Print Network [OSTI]

    Research for the South Climate research, equatorial Andes #12;··· Priority programmes ··· Science activity, such as atmosphe- ric and environmental pollution. To reduce the impact of human activities

  9. University Research Ins0tutes (URIs) Research Centres (RCs)

    E-Print Network [OSTI]

    Martin, Ralph R.

    Seafarers Interna0onal Research Centre Skills, Knowledge and Organisa0onal performance & Methods (WISERD) Cardiff Interdisciplinary Energy Research Network Wales

  10. Research at LAMPF

    SciTech Connect (OSTI)

    Not Available

    1992-02-01T23:59:59.000Z

    During the past decade, both the science program and the experimental facilities at LAMPF have undergone some significant changes. This report is a concise description of the current research initiatives and of new directions being proposed for the future research program at LAMPF. Traditionally the LAMPF physics program has explored nuclear systems with hadronic probes: pions, protons, and neutrons. In recent years the exploitation of the intense lepton beams -- neutrinos and muons -- at LAMPF has received increasing emphasis. Explorations of issues in electroweak physics and precision tests of quantum electrodynamics have been significant areas of experimentation. A new concept of the program is an increased emphasis on the role of weak interactions in hadronic systems. Here the electroweak force is treated as a well-understood interaction, which can be used to reveal the wave functions and properties of hadronic systems. The manifestations of the electroweak force may be discussed either in the language of quarks interacting through the exchange of W and Z bosons or in terms of nucleons interacting through the exchange of mesons described by both strong and weak coupling constants. Taken together, these topics provide a rich and vital program of fundamental interest in nuclear physics. Atomic physics, astrophysics, materials research, among others, are additional components of the LAMPF-LANSCE experimental activities. Research highlights of this broad program and the research tools available at LAMPF are described briefly in this report.

  11. Sandia Combustion Research Program

    SciTech Connect (OSTI)

    Johnston, S.C.; Palmer, R.E.; Montana, C.A. (eds.)

    1988-01-01T23:59:59.000Z

    During the late 1970s, in response to a national energy crisis, Sandia proposed to the US Department of Energy (DOE) a new, ambitious program in combustion research. Shortly thereafter, the Combustion Research Facility (CRF) was established at Sandia's Livermore location. Designated a ''user facility,'' the charter of the CRF was to develop and maintain special-purpose resources to support a nationwide initiative-involving US inventories, industry, and national laboratories--to improve our understanding and control of combustion. This report includes descriptions several research projects which have been simulated by working groups and involve the on-site participation of industry scientists. DOE's Industry Technology Fellowship program, supported through the Office of Energy Research, has been instrumental in the success of some of these joint efforts. The remainder of this report presents results of calendar year 1988, separated thematically into eleven categories. Referred journal articles appearing in print during 1988 and selected other publications are included at the end of Section 11. Our traditional'' research activities--combustion chemistry, reacting flows, diagnostics, engine and coal combustion--have been supplemented by a new effort aimed at understanding combustion-related issues in the management of toxic and hazardous materials.

  12. Nuclear Energy Research Brookhaven National

    E-Print Network [OSTI]

    Ohta, Shigemi

    Nuclear Energy Research Brookhaven National Laboratory William C. Horak, Chair Nuclear Science and Technology Department #12;BNL Nuclear Energy Research Brookhaven Graphite Research Reactor - 1948 National Nuclear Data Center - 1952* High Flux Beam Reactor - 1964 Technical Support for NRC - 1974

  13. Clinical & Translational Research Scholars Programme

    E-Print Network [OSTI]

    Clinical & Translational Research Scholars Programme PhD Scholarship Applications Invited A unique cross-institutional structured PhD programme, integrated with industry and clinical research centres Clinical & Translational Research Scholars Programme. The successful candidates will commence studies

  14. NREL Buildings Research Video

    ScienceCinema (OSTI)

    None

    2013-05-29T23:59:59.000Z

    Through research, the National Renewable Energy Laboratory (NREL) has developed many strategies and design techniques to ensure both commercial and residential buildings use as little energy as possible and also work well with the surroundings. Here you will find a video that introduces the work of NREL Buildings Research, highlights some of the facilities on the NREL campus, and demonstrates these efficient building strategies. Watch this video to see design highlights of the Science and Technology Facility on the NREL campus?the first Federal building to be LEED® Platinum certified. Additionally, the video demonstrates the energy-saving features of NRELs Thermal Test Facility. For a text version of this video visit http://www.nrel.gov/buildings/about_research_text_version.html

  15. Guide to research facilities

    SciTech Connect (OSTI)

    Not Available

    1993-06-01T23:59:59.000Z

    This Guide provides information on facilities at US Department of Energy (DOE) and other government laboratories that focus on research and development of energy efficiency and renewable energy technologies. These laboratories have opened these facilities to outside users within the scientific community to encourage cooperation between the laboratories and the private sector. The Guide features two types of facilities: designated user facilities and other research facilities. Designated user facilities are one-of-a-kind DOE facilities that are staffed by personnel with unparalleled expertise and that contain sophisticated equipment. Other research facilities are facilities at DOE and other government laboratories that provide sophisticated equipment, testing areas, or processes that may not be available at private facilities. Each facility listing includes the name and phone number of someone you can call for more information.

  16. Tansmutation Research program

    SciTech Connect (OSTI)

    Seidler, Paul

    2011-07-31T23:59:59.000Z

    Six years of research was conducted for the United States Department of Energy, Office of Nuclear Energy between the years of 2006 through 2011 at the University of Nevada, Las Vegas (UNLV). The results of this research are detailed in the narratives for tasks 1-45. The work performed spanned the range of experimental and modeling efforts. Radiochemistry (separations, waste separation, nuclear fuel, remote sensing, and waste forms) , material fabrication, material characterization, corrosion studies, nuclear criticality, sensors, and modeling comprise the major topics of study during these six years.

  17. PNNL Coal Gasification Research

    SciTech Connect (OSTI)

    Reid, Douglas J.; Cabe, James E.; Bearden, Mark D.

    2010-07-28T23:59:59.000Z

    This report explains the goals of PNNL in relation to coal gasification research. The long-term intent of this effort is to produce a syngas product for use by internal Pacific Northwest National Laboratory (PNNL) researchers in materials, catalysts, and instrumentation development. Future work on the project will focus on improving the reliability and performance of the gasifier, with a goal of continuous operation for 4 hours using coal feedstock. In addition, system modifications to increase operational flexibility and reliability or accommodate other fuel sources that can be used for syngas production could be useful.

  18. Research | Jefferson Lab

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclear Press ReleasesIn the Inorganic PV thrust,Research Home

  19. Research | The Ames Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclear Press ReleasesIn the Inorganic PVResearch The U.S.Research

  20. Research Groups - Cyclotron Institute

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Scienceand Requirements Recently ApprovedReliabilityPrincipalResearch Finds VitaminResearch Groups

  1. Optimized Algorithms Boost Combustion Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Optimized Algorithms Boost Combustion Research Optimized Algorithms Boost Combustion Research Methane Flame Simulations Run 6x Faster on NERSC's Hopper Supercomputer November 25,...

  2. Nuclear Safety Research and Development...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Nuclear Safety Research and Development Proposal Review and Prioritization Process and Criteria Nuclear Safety Research and Development Program Office of Nuclear Safety Office of...

  3. Saskatchewan Petroleum Research Incentive (SPRI)

    Broader source: Energy.gov [DOE]

    The Saskatchewan Petroleum Research Incentive is intended to encourage research, development and demonstration of new technologies that facilitate the expanded production of Saskatchewan's oil and...

  4. RESEARCH PERSONNEL AND ENGINEERING STAFF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    8 RESEARCH PERSONNEL AND ENGINEERING STAFF April 1, 2004 - March 31, 2005 Faculty and Research Group Leaders Carl A. Gagliardi, Professor of Physics John C. Hardy, Professor of...

  5. RESEARCH PERSONNEL AND ENGINEERING STAFF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    RESEARCH PERSONNEL AND ENGINEERING STAFF April 1, 2001 - March 31, 2002 FACULTY AND RESEARCH GROUP LEADERS Carl A. Gagliardi Professor of Physics John C. Hardy Professor of Physics...

  6. RESEARCH PERSONNEL AND ENGINEERING STAFF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    10 - March 31, 2011 Faculty and Research Group Leaders Aldo Bonasera, Research Scientist Charles M. Folden III, Assist. Prof. of Nuclear Chemistry Rainer Fries, Assist. Professor...

  7. New research, publications and videos

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    New research, publications and videos Alumni Link: Opportunities, News and Resources for Former Employees Latest Issue:March 2015 All Issues submit New research, publications...

  8. Cooperative Research & Development Agreements | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    CRADA SHARE Cooperative Research and Development Agreement A Cooperative Research and Development Agreement (CRADA) allows non-federal entities (industry, universities,...

  9. A Comparison of Amplitude-Based and Phase-Based Positron Emission Tomography Gating Algorithms for Segmentation of Internal Target Volumes of Tumors Subject to Respiratory Motion

    SciTech Connect (OSTI)

    Jani, Shyam S., E-mail: sjani@mednet.ucla.edu [Department of Radiation Oncology, David Geffen School of Medicine, University of California, Los Angeles, California (United States); Robinson, Clifford G. [Department of Radiation Oncology, Siteman Cancer Center, Washington University in St Louis, St Louis, Missouri (United States); Dahlbom, Magnus [Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, California (United States); White, Benjamin M.; Thomas, David H.; Gaudio, Sergio; Low, Daniel A.; Lamb, James M. [Department of Radiation Oncology, David Geffen School of Medicine, University of California, Los Angeles, California (United States)

    2013-11-01T23:59:59.000Z

    Purpose: To quantitatively compare the accuracy of tumor volume segmentation in amplitude-based and phase-based respiratory gating algorithms in respiratory-correlated positron emission tomography (PET). Methods and Materials: List-mode fluorodeoxyglucose-PET data was acquired for 10 patients with a total of 12 fluorodeoxyglucose-avid tumors and 9 lymph nodes. Additionally, a phantom experiment was performed in which 4 plastic butyrate spheres with inner diameters ranging from 1 to 4 cm were imaged as they underwent 1-dimensional motion based on 2 measured patient breathing trajectories. PET list-mode data were gated into 8 bins using 2 amplitude-based (equal amplitude bins [A1] and equal counts per bin [A2]) and 2 temporal phase-based gating algorithms. Gated images were segmented using a commercially available gradient-based technique and a fixed 40% threshold of maximum uptake. Internal target volumes (ITVs) were generated by taking the union of all 8 contours per gated image. Segmented phantom ITVs were compared with their respective ground-truth ITVs, defined as the volume subtended by the tumor model positions covering 99% of breathing amplitude. Superior-inferior distances between sphere centroids in the end-inhale and end-exhale phases were also calculated. Results: Tumor ITVs from amplitude-based methods were significantly larger than those from temporal-based techniques (P=.002). For lymph nodes, A2 resulted in ITVs that were significantly larger than either of the temporal-based techniques (P<.0323). A1 produced the largest and most accurate ITVs for spheres with diameters of ?2 cm (P=.002). No significant difference was shown between algorithms in the 1-cm sphere data set. For phantom spheres, amplitude-based methods recovered an average of 9.5% more motion displacement than temporal-based methods under regular breathing conditions and an average of 45.7% more in the presence of baseline drift (P<.001). Conclusions: Target volumes in images generated from amplitude-based gating are larger and more accurate, at levels that are potentially clinically significant, compared with those from temporal phase-based gating.

  10. Research at the University of Bayreuth Research Priorities // Projects // Achievements

    E-Print Network [OSTI]

    Ullmann, G. Matthias

    Economics Research Centre for German and European Energy Law (FER) Institute of Medical Care Management picture: The "Solar Sphere" at the School of Engineering (F. Lechner, 1999) #12;Research at the University Centre for German and European Food Law Research Centre of Food Quality (ForN) Research Centre of Capital

  11. Forest Research Dyfi Catchment and Woodland Research Platform

    E-Print Network [OSTI]

    Forest Research Dyfi Catchment and Woodland Research Platform The Dyfi Catchment and Woodland Research Platform is a collaborative initiative that focuses on the study of multi-functional landscapes and tourism. The Dyfi Catchment and Woodland Research Platform is data-rich. Both existing and new data

  12. Honorary Edition Potato Research

    E-Print Network [OSTI]

    Douches, David S.

    , chipping (out-of-the-field, storage, and extended cold storage) and cooking quality, bruise resistance single person has done so much for the potato industry. His vision and attention to detail have helped advance the industry's research and education programs not only in Michigan but nationwide. Our thanks

  13. NEUROROBOTICS ORIGINAL RESEARCH ARTICLE

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    -inspiration, prefrontal cortex INTRODUCTION In controlled environments (e.g., industrial applications), robots can achieve is to liberate robots from controlled industrial settings, and allow them to interact with humans and changingNEUROROBOTICS ORIGINAL RESEARCH ARTICLE published: 1 July 2011 doi: 10.3389/fnbot.2011.00001 Robot

  14. Biomass Research Program

    SciTech Connect (OSTI)

    Kenney, Kevin; Wright, Christopher; Shelton-Davis, Colleen

    2011-01-01T23:59:59.000Z

    INL's mission is to achieve DOE's vision of supplying high-quality raw biomass; preprocessing biomass into advanced bioenergy feedstocks; and delivering bioenergy commodities to biorefineries. You can learn more about research like this at the lab's facebook site http://www.facebook.com/idahonationallaboratory.

  15. Hypertension Research Division

    E-Print Network [OSTI]

    Berdichevsky, Victor

    Hypertension & Vascular Research Division Department of Internal Medicine Jeffrey L. Garvin, Ph.D. ­ Division Head #12;Prevalence of Hypertension in U.S. Men by Age and Ethnicity 18 ­ 29 30 ­ 39 40 ­ 49 50 Prevalence of High BP Adapted from Burt et al. Hypertension 1995;25:305. 25 50 75 #12;Introduction

  16. RESEARCH IN PARTICLE PHYSICS

    SciTech Connect (OSTI)

    Kearns, Edward [Boston Universiy] [Boston Universiy

    2013-07-12T23:59:59.000Z

    This is the final report for the Department of Energy Grant to Principal Investigators in Experimental and Theoretical Particle Physics at Boston University. The research performed was in the Energy Frontier at the LHC, the Intensity Frontier at Super-Kamiokande and T2K, the Cosmic Frontier and detector R&D in dark matter detector development, and in particle theory.

  17. Digital Business RESEARCH BRIEF

    E-Print Network [OSTI]

    Center for Digital Business RESEARCH BRIEF Volume XIII Number 2 May 2011 2011 MIT Center for Digital Business, E. Brynjolfsson The 4 Ways IT is Driving Innovation Erik Brynjolfsson, Director, MIT Center for Digital Business and Schussel Professor, MIT Sloan School of Management Reprinted from Sloan

  18. Research Councils UK materials

    E-Print Network [OSTI]

    Berzins, M.

    as completely new materials such as super-strong graphene, or developments of traditional materials such as graphene is still being realised, with the Research Councils investing in both the further exploitation to UK growth. For example, the 2004 `discovery' of wonder-material graphene sparked a host of global

  19. Environmental Research Center to

    E-Print Network [OSTI]

    Environmental Research Center to Celebrate 20 years Symposium and gala are planned, sustainable fuels, transportation systems, and solar energy By Sean Nealon On MAY 10, 2012 The world's largest indoor environmental chamber at the RIVERSIDE, Calif. (www.ucr.edu) -- The College of Engineering

  20. INTERNATIONAL PACIFIC RESEARCH CENTER

    E-Print Network [OSTI]

    Wang, Yuqing

    INTERNATIONAL PACIFIC RESEARCH CENTER APRIL 2005­MARCH 2006 REPORT SCHOOL OF OCEAN AND EARTH Center 1 The Year's Highlights 3 Indo-Pacific Ocean Climate 4 Regional-Ocean Influences 10 Asian Ocean Climate: To understand climate variations in the Pacific and Indian oceans on interannual

  1. Market Research Berkeley FIRST

    E-Print Network [OSTI]

    Kammen, Daniel M.

    Market Research Berkeley FIRST i dDevi Prasad Dt: 03/25/2008 #12;2 Customer Survey Goalsy 1;4 Purchase factors (211 responses) In the recent past, when you have been offered services by solar electric or solar hot water vendors and/or home efficiency improvement contractors....... · Understood all aspects

  2. Research Summary Carbon Additionality

    E-Print Network [OSTI]

    of the quality assurance of emissions reduction and carbon sequestration activities, but remains a source of muchResearch Summary Carbon Additionality Additionality is widely considered to be a core aspect controversy in national carbon accounting, international regulatory frameworks and carbon markets. A review

  3. Operations Research + Information Engineering

    E-Print Network [OSTI]

    Keinan, Alon

    and the equipment they operate to perform most efficiently. The allocation of resources may be represented of the techniques and modeling concepts needed to analyze and design complex systems. As an operations researcher. All business systems are complex and need sophisticated decision-making methods that enable employees

  4. IBM Research Report

    E-Print Network [OSTI]

    2009-03-02T23:59:59.000Z

    Feb 20, 2009 ... An Efficient Decomposition Algorithm for Static, Stochastic, ... Business Analytics & Mathematical Sciences, IBM Research. 1101 ... such as resource planning, capacity allocation, portfolio analysis, etc. ... bound imposed upon the risk measure for modeling the maximum acceptable risk that one is willing.

  5. Introduction Research Interests

    E-Print Network [OSTI]

    Blais, Brian

    Resources Projects for Collaboration B. Blais (bblais@bryant.edu) Department of Science and Technology Bryant University Bryant-China University of Geosciences Joint Research - November 2007 B. Blais (bblais@bryant of the Brain Computer interfacing Bayesian Statistics B. Blais (bblais@bryant.edu) Statistics and Environmental

  6. PSYCHOLOGICAL SCIENCE Research Article

    E-Print Network [OSTI]

    Aslin, Richard N.

    another. First, both types of learning appear to be age- invariant, with young grade-school-aged childrenPSYCHOLOGICAL SCIENCE Research Article ESCIDENTAL LANGUAGE LEARNING: Listening (and Leaming) out and adults on an incidental language-learning task. Learning entailed word segmentation from continuous

  7. Research Training 22

    E-Print Network [OSTI]

    Takahashi, Ryo

    of CAE Activity in the Vehicle Development) CAE NV(Noise and vibration) CFD(Computational fluid / Denso / Nissan / Mitsubishi Motors / Mitsubishi Electronics / Toyota Central Research Lab. Group project (Fuel cell Lab., Crash Dummy Lab.) 2.Toyota Motors Co. (Car Production Line, Exhibition Hall ) 3

  8. Fifteenth combustion research conference

    SciTech Connect (OSTI)

    NONE

    1993-06-01T23:59:59.000Z

    The BES research efforts cover chemical reaction theory, experimental dynamics and spectroscopy, thermodynamics of combustion intermediates, chemical kinetics, reaction mechanisms, combustion diagnostics, and fluid dynamics and chemically reacting flows. 98 papers and abstracts are included. Separate abstracts were prepared for the papers.

  9. Annual Report of Research

    E-Print Network [OSTI]

    Lee, Dongwon

    the Department of Defense increased 2.5 percent to $149 million. Funding from the Department of Energy increased;2 Overview.............................. 3 Statistical Snapshot............. 4 Sponsored Research Highlights--from developing sources of renewable energy to improving homeland security. Increasingly, doing so requires

  10. Research Article Phonological Dyslexia

    E-Print Network [OSTI]

    Research Article Phonological Dyslexia A Test Case for Reading Models Elise Caccappolo-van Vliet,1 words, a type of deficit referred to as phonological dyslexia. We report on 2 individuals with Alzheimer's disease who show phonological dyslexia. Although highly accurate in reading familiar words aloud (even

  11. november 2010 Student Research

    E-Print Network [OSTI]

    Papautsky, Ian

    November 2010 ResearchUc #12;2 UCReseaRch November 2010 Design vs. Dyslexia Reading and retaining information is the challenge faced by the one in five children who has some form of dyslexia. Overcoming movement to increase the reading and retention abilities of children aged 9 to 11 who have dyslexia

  12. National Research Council Canada

    E-Print Network [OSTI]

    Fleming, Michael W.

    National Research Council Canada Institute for Information Technology Conseil national de recherches Canada Institut de technologie de l'information Determining Internet Users' Values for Private in The Second Annual Conference on Privacy, Security and Trust (PST'04). Fredericton, New Brunswick, Canada

  13. Biological and Environmental Research

    E-Print Network [OSTI]

    recalcitrance. Using an integrated approach to solving the challenge of producing biofuel from cellulosic materials, the center will not only provide the scientific basis for affordable and sustainable biofuel but will also advance our understanding in areas of fundamental biological science. BESC researchers have

  14. Cancer Research Beckman Institute

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    Cancer Research Beckman Institute FOR ADVANCED SCIENCE AND TECHNOLOGY #12;T The medical and scientific worlds have known for many years that in order to truly understand and treat cancer, the fight has and cancerous tumors have to first be visualized at the smallest scales possible, and then treated in the most

  15. Education research Primary Science

    E-Print Network [OSTI]

    Rambaut, Andrew

    Education research Primary Science Survey Report December 2011 #12;Primary Science Survey Report, Wellcome Trust 1 Background In May 2009 Key Stage 2 science SATs (Standard Assessment Tests) were abolished fiasco might occur, where the results were delayed and their quality questioned. The loss of science SATs

  16. Research Symposium January 2005

    E-Print Network [OSTI]

    Walter, M.Todd

    sustainable management. Research in nine villages, provided a comparison of two areas representing a high of the resource. Management of NWFPs in Community Forests may represent a viable option for sustainable management Resources Cornell University Kate Ballantine Soil organic matter accumulation in New York restored wetlands

  17. Research and Observation

    E-Print Network [OSTI]

    Worrest, Robert C.

    half of the world's focused climate change ence. As an input to this review, the U.S. research climate. With respect to specific areas of · monitor, understand, and predict Agriculture, Commerce- that greenhouse gases are accumulating · provide a sound scientific basis for tion), Defense, Energy, Health

  18. Research Strategy February 2014

    E-Print Network [OSTI]

    Paxton, Anthony T.

    3.1 Priority areas of research Marine Renewable Energy The marine group has an established track in each discipline. 3. The School has a number of strategic international network connectionsA27) and Town & Country Planning (UoA31). The outcome is summarised in Table 1. Table 1 Percentage

  19. Academic Writing Research Papers

    E-Print Network [OSTI]

    Be cautious with what you find on the World Wide Web! #12;Handout revised: August 10, 2009 TM Use started: Understand the assignment Determine the objectives and scope Look for key words that describe? Strategies for making sense of your research sources: Use KEY WORDS to help you organize your materials

  20. --Multiobjective Optimization --RESEARCH REPORT

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    The single objective assignment problem (AP) is an integer programming problem that can be solved as a linear-- Multiobjective Optimization -- RESEARCH REPORT No 05.07 December 2005 The Biobjective Assignment;Anthony Przybylski, Xavier Gandibleux, Matthias Ehrgott The Biobjective Assignment Problem 34 p. Les

  1. Research paper Introduction

    E-Print Network [OSTI]

    Bern, Universität

    Research paper Introduction The need for protected areas to preserve biodiversity, natural or near. Mostly for economic reasons, protected areas such as natural parks and reserves were often selected of such conservation efforts is the protection of landscapes with (presumed) ecological integrity and naturalness

  2. Biomass Research Program

    ScienceCinema (OSTI)

    Kenney, Kevin; Wright, Christopher; Shelton-Davis, Colleen

    2013-05-28T23:59:59.000Z

    INL's mission is to achieve DOE's vision of supplying high-quality raw biomass; preprocessing biomass into advanced bioenergy feedstocks; and delivering bioenergy commodities to biorefineries. You can learn more about research like this at the lab's facebook site http://www.facebook.com/idahonationallaboratory.

  3. 885RESEARCH ARTICLE INTRODUCTION

    E-Print Network [OSTI]

    Villefranche sur mer

    885RESEARCH ARTICLE INTRODUCTION Entry into and exit from mitosis is regulated by cyclin cell cycles is that directionality is provided by cyclin B destruction rendering exit from M phase, during meiosis, two M phases occur one after the other. Moreover, akin to mitotic exit, exit from meoisis

  4. Digital Business RESEARCH BRIEF

    E-Print Network [OSTI]

    of social software, and a July 2009 Prescient digital media survey revealed that 47% of respondents wereCenter for Digital Business RESEARCH BRIEF Volume XIII Number 1 May 2011 2011 MIT Center for Digital Business, A. McAfee Shattering the Myths About Enterprise 2.0 Andrew P. McAfee, Associate Director

  5. Powertrain & Vehicle Research Centre

    E-Print Network [OSTI]

    Burton, Geoffrey R.

    Powertrain & Vehicle Research Centre Low Carbon Powertrain Development S Akehurst, EPSRC Advanced Viewing Trade-Offs and Finding Optima Realism Advanced Engine Test Vehicle Test Rolling Road Powertrain Simulation Basic Engine Test Vehicle Test Cost & Complexity Towards Final Product Lean Powertrain Development

  6. Research Cloud Computing Recommendations

    E-Print Network [OSTI]

    Qian, Ning

    Research Cloud Computing Recommendations SRCPAC December 3, 2014 #12;Mandate and Membership SRCPAC convened this committee in Sept 2014 to investigate the role that cloud computing should play in our & Academic Affairs (Social Work) #12;Questions discussed · What cloud resources are available? · Which kinds

  7. EPRI's Photovoltaic Research Needs

    E-Print Network [OSTI]

    Homes, Christopher C.

    output data synthesis for plants not yet built 3 4 5 6 7 kW Customer Load Customer PV (-) · Disturbance Executive Planning Workshop for a New Northeast Solar Energy Research Center January 11-12, 2011 #12;About · Efficiency due to learning · Reduction in BOP · 600V DC vs 1000V DC Courtesy of First Solar EPRI

  8. . RESEARCH PAPER . SCIENCE CHINA

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    . RESEARCH PAPER . SCIENCE CHINA Information Sciences January 2013, Vol. 56 012104:1­012104:10 doi: 10.1007/s11432-012-4616-5 c Science China Press and Springer-Verlag Berlin Heidelberg 2012 info, Tsinghua University, Beijing 100084, China; 2Beijing Aerospace Control Center, Beijing 100094, China; 3

  9. Research Highlights Nature Nanotechnology

    E-Print Network [OSTI]

    Müller, Markus

    © 2009 APS Research Highlights Nature Nanotechnology Published online: 17 July 2009 | doi:10 perfect fluid. Phys. Rev. Lett. 103, 025301 (2009). | Article |1. Nature Nanotechnology ISSN 1748 : Nature Nanotechnology http://www.nature.com/nnano/reshigh/2009/0709/full/nnano.2009.222.html 1 of 1 18

  10. Base Research Program

    SciTech Connect (OSTI)

    Everett Sondreal; John Hendrikson

    2009-03-31T23:59:59.000Z

    In June 2009, the Energy & Environmental Research Center (EERC) completed 11 years of research under the U.S. Department of Energy (DOE) Base Cooperative Agreement No. DE-FC26-98FT40320 funded through the Office of Fossil Energy (OFE) and administered at the National Energy Technology Laboratory (NETL). A wide range of diverse research activities were performed under annual program plans approved by NETL in seven major task areas: (1) resource characterization and waste management, (2) air quality assessment and control, (3) advanced power systems, (4) advanced fuel forms, (5) value-added coproducts, (6) advanced materials, and (7) strategic studies. This report summarizes results of the 67 research subtasks and an additional 50 strategic studies. Selected highlights in the executive summary illustrate the contribution of the research to the energy industry in areas not adequately addressed by the private sector alone. During the period of performance of the agreement, concerns have mounted over the impact of carbon emissions on climate change, and new programs have been initiated by DOE to ensure that fossil fuel resources along with renewable resources can continue to supply the nation's transportation fuel and electric power. The agreement has addressed DOE goals for reductions in CO{sub 2} emissions through efficiency, capture, and sequestration while expanding the supply and use of domestic energy resources for energy security. It has further contributed to goals for near-zero emissions from highly efficient coal-fired power plants; environmental control capabilities for SO{sub 2}, NO{sub x}, fine respirable particulate (PM{sub 2.5}), and mercury; alternative transportation fuels including liquid synfuels and hydrogen; and synergistic integration of fossil and renewable resources (e.g., wind-, biomass-, and coal-based electrical generation).

  11. Load research manual. Volume 3. Load research for advanced technologies

    SciTech Connect (OSTI)

    None

    1980-11-01T23:59:59.000Z

    This three-volume manual presents technical guidelines for electric utility load research. Special attention is given to issues raised by the load data reporting requirements of the Public Utility Regulatory Policies Act of 1978 and to problems faced by smaller utilities that are initiating load research programs. The manual includes guides to load research literature and glossaries of load research and statistical terms. In Volume 3, special load research procedures are presented for solar, wind, and cogeneration technologies.

  12. SCHOOL OF MEDICINE RESEARCH ROADMAP

    E-Print Network [OSTI]

    Chapman, Michael S.

    SCHOOL OF MEDICINE RESEARCH ROADMAP October 2011 #12;OHSU School of Medicine Research Roadmap internal and external stakeholders and the public. #12;OHSU School of Medicine Research Roadmap October human health and well-being. At the Research Roadmap Retreat in December 2010, I issued a charge

  13. Research Infrastructures in Horizon 2020

    E-Print Network [OSTI]

    Schettini, Raimondo

    , sustainable agriculture, marine - maritime research, bio-economy Secure, clean and efficient energy Smart

  14. for public engagement with research

    E-Print Network [OSTI]

    Berzins, M.

    engagement with schools becomes a standard part of skills development opportunities on offer to researchers

  15. Managing and Archiving Research Documents

    E-Print Network [OSTI]

    Johannesson, Henrik

    Managing and Archiving Research Documents Summary of "Hantering och arkivering av Documents ­ A Handbook for the Research Activity at the University of Gothenburg) #12;Managing and Archiving a method to manage and archive research documents1 . A project group of approximately 20 researchers formed

  16. UNIVERSITY BOULEVARD FAU Research Facility

    E-Print Network [OSTI]

    Fernandez, Eduardo

    Harriet L.Wilkes Honors College FAU Research Facility Expansion Satellite Utility Plant Chiller Lift

  17. Seven principles for strengthening research

    E-Print Network [OSTI]

    Rambaut, Andrew

    Interventions of Poverty-related Diseases (NACCAP) African Poverty-related Infection Oriented Research

  18. Systems Engineering Advancement Research Initiative

    E-Print Network [OSTI]

    de Weck, Olivier L.

    Systems Engineering Advancement Research Initiative RESEARCH PORTFOLIO Fall 2008 About SEAri http://seari.mit.edu The Systems Engineering Advancement Research Initiative brings together a set of sponsored research projects and a consortium of systems engineering leaders from industry, government, and academia. SEAri is positioned within

  19. Binding of the Respiratory Chain Inhibitor Antimycin to theMitochondrial bc1 Complex: A New Crystal Structure Reveals an AlteredIntramolecular Hydrogen-Bonding Pattern

    SciTech Connect (OSTI)

    Huang, Li-shar; Cobessi, David; Tung, Eric Y.; Berry, Edward A.

    2005-05-10T23:59:59.000Z

    Antimycin A (antimycin), one of the first known and most potent inhibitors of the mitochondrial respiratory chain, binds to the quinone reduction site of the cytochrome bc1 complex.Structure-activity-relationship studies have shown that the N-formylamino-salicyl-amide group is responsible for most of the binding specificity, and suggested that a low pKa for the phenolic OH group and an intramolecular H-bond between that OH and the carbonyl O of the salicylamide linkage are important. Two previous X-ray structures of antimycin bound to vertebrate bc1 complex gave conflicting results. A new structure reported here of the bovine mitochondrial bc1 complex at 2.28Angstrom resolution with antimycin bound, allows us for the first time to reliably describe the binding of antimycin and shows that the intramolecular hydrogen bond described in solution and in the small-molecule structure is replaced by one involving the NH rather than carbonyl O of the amide linkage, with rotation of the amide group relative to the aromatic ring. The phenolic OH and formylamino N form H-bonds with conserved Asp228 of cyt b, and the formylamino O H-bonds via a water molecule to Lys227. A strong density the right size and shape for a diatomic molecule is found between the other side of the dilactone ring and the alpha-A helix.

  20. Associations of indoor carbon dioxide concentrations and environmental susceptibilities with mucous membrane and lower respiratory building related symptoms in the BASE study: Analyses of the 100 building dataset

    SciTech Connect (OSTI)

    Erdmann, Christine A.; Apte, Michael G.

    2003-09-01T23:59:59.000Z

    Using the US EPA 100 office-building BASE Study dataset, they conducted multivariate logistic regression analyses to quantify the relationship between indoor CO{sub 2} concentrations (dCO{sub 2}) and mucous membrane (MM) and lower respiratory system (LResp) building related symptoms, adjusting for age, sex, smoking status, presence of carpet in workspace, thermal exposure, relative humidity, and a marker for entrained automobile exhaust. In addition, they tested the hypothesis that certain environmentally-mediated health conditions (e.g., allergies and asthma) confer increased susceptibility to building related symptoms within office buildings. Adjusted odds ratios (ORs) for statistically significant, dose-dependent associations (p < 0.05) for dry eyes, sore throat, nose/sinus congestion, and wheeze symptoms with 100 ppm increases in dCO{sub 2} ranged from 1.1 to 1.2. These results suggest that increases in the ventilation rates per person among typical office buildings will, on average, reduce the prevalence of several building related symptoms by up to 70%, even when these buildings meet the existing ASHRAE ventilation standards for office buildings. Building occupants with certain environmentally-mediated health conditions are more likely to experience building related symptoms than those without these conditions (statistically significant ORs ranged from 2 to 11).

  1. Epidemiological-environemental study of lead acid battery workers. III. Chronic effects of sulfuric acid on the respiratory system and teeth

    SciTech Connect (OSTI)

    Gamble, J.; Jones, W.; Hancock, J.; Meckstroth, R.L.

    1984-10-01T23:59:59.000Z

    The effects of long-term exposure to sulfuric acid mist on the teeth and respiratory system were studied in 248 workers in five plants manufacturing lead acid batteries. The prevalence of cough, phlegm, dyspnea, and wheezing as determined by questionnaire were not associated with estimates of cumulative acid exposure. There was only one case of irregular opacities seen on the chest radiographs. There was no statistically significant association of reduced FEV/sub 1/ peak flow, FEF/sub 50/, and FEF/sub 75/ with acid exposure although the higher exposed group had lower mean values. FVC in the high exposure group showed a statistically significant reductioon compared to the low exposure group but there was no significant association when exposure was analyzed as a continuous variable. The ratio of observed to expected prevalence of teeth etching and erosion was about four times greater in the high acid-exposure group. The earliest case of etching occured after 4 months exposure to an estimated average exposure of 0.23 mg/m/sup 3/ sulfuric acid.

  2. Microdistribution and Long-Term Retention of 239Pu (NO3)4 in the Respiratory Tracts of an Acutely Exposed Plutonium Worker and Experimental Beagle Dogs

    SciTech Connect (OSTI)

    Nielsen, Christopher E.; Wilson, Dulaney A.; Brooks, Antone L.; McCord, Stacey; Dagle, Gerald E.; James, Anthony C.; Tolmachev, Sergei Y.; Thrall, Brian D.; Morgan, William F.

    2012-11-01T23:59:59.000Z

    The long-term retention of inhaled soluble forms of plutonium raises concerns as to the potential health effects in persons working in nuclear energy or the nuclear weapons program. The distributions of long-term retained inhaled plutonium-nitrate [239Pu (NO3)4] deposited in the lungs of an accidentally exposed nuclear worker (Human Case 0269) and in the lungs of experimentally exposed beagle dogs with varying initial lung depositions were determined via autoradiographs of selected histological lung, lymph node, trachea, and nasal turbinate tissue sections. These studies showed that both the human and dogs had a non-uniform distribution of plutonium throughout the lung tissue. Fibrotic scar tissue effectively encapsulated a portion of the plutonium and prevented its clearance from the body or translocation to other tissues and diminished dose to organ parenchyma. Alpha radiation activity from deposited plutonium in Human Case 0269 was observed primarily along the sub-pleural regions while no alpha activity was seen in the tracheobronchial lymph nodes of this individual. However, relatively high activity levels in the tracheobronchial lymph nodes of the beagles indicated the lymphatic system was effective in clearing deposited plutonium from the lung tissues. In both the human case and beagle dogs, the appearance of retained plutonium within the respiratory tract was inconsistent with current biokinetic models of clearance for soluble forms of plutonium. Bound plutonium can have a marked effect on the dose to the lungs and subsequent radiation exposure has the potential increase in cancer risk.

  3. Photonics Research and Development

    SciTech Connect (OSTI)

    Pookpanratana, Sujitra; Shlayan, Neveen; Venkat, Rama; Das, Bisjwajit; Boehm, Bob; Heske, Clemens; Fraser, Donald; Moustakas, Theodore

    2010-01-15T23:59:59.000Z

    During the period August 2005 through October 2009, the UNLV Research Foundation (UNLVRF), a non-profit affiliate of the University of Nevada, Las Vegas (UNLV), in collaboration with UNLVâ??s Colleges of Science and Engineering; Boston University (BU); Oak Ridge National Laboratory (ORNL); and Sunlight Direct, LLC, has managed and conducted a diverse and comprehensive research and development program focused on light-emitting diode (LED) technologies that provide significantly improved characteristics for lighting and display applications. This final technical report provides detailed information on the nature of the tasks, the results of the research, and the deliverables. It is estimated that about five percent of the energy used in the nation is for lighting homes, buildings and streets, accounting for some 25 percent of the average homeâ??s electric bill. However, the figure is significantly higher for the commercial sector. About 60 percent of the electricity for businesses is for lighting. Thus replacement of current lighting with solid-state lighting technology has the potential to significantly reduce this nationâ??s energy consumption â?? by some estimates, possibly as high as 20%. The primary objective of this multi-year R&D project has been to develop and advance lighting technologies to improve national energy conversion efficiencies; reduce heat load; and significantly lower the cost of conventional lighting technologies. The UNLVRF and its partners have specifically focused these talents on (1) improving LED technologies; (2) optimizing hybrid solar lighting, a technology which potentially offers the benefits of blending natural with artificial lighting systems, thus improving energy efficiency; and (3) building a comprehensive academic infrastructure within UNLV which concentrates on photonics R&D. Task researchers have reported impressive progress in (1) the development of quantum dot laser emitting diodes (QDLEDs) which will ultimately improve energy efficiency and lower costs for display and lighting applications (UNLV College of Engineering); (2) advancing green LED technology based on the Indium-Gallium-Nitride system (BU), thus improving conversion efficiencies; (3) employing unique state-of-the-art X-ray, electron and optical spectroscopies with microscopic techniques to learn more about the electronic structure of materials and contacts in LED devices (UNLV College of Science); (4) establishing a UNLV Display Lighting Laboratory staffed with a specialized team of academic researchers, students and industrial partners focused on identifying and implementing engineering solutions for lighting display-related problems; and (5) conducting research, development and demonstration for HSL essential to the resolution of technological barriers to commercialization.

  4. Energy Efficiency and Renewable Energy Postdoctoral Research...

    Office of Environmental Management (EM)

    Postdoctoral Research Awards Energy Efficiency and Renewable Energy Postdoctoral Research Awards Contacts Energy Efficiency and Renewable Energy Postdoctoral Research Awards...

  5. Marketing Strategy Research

    SciTech Connect (OSTI)

    None

    2010-03-31T23:59:59.000Z

    This report documents the research that has been undertaken as background for preparation of a marketing campaign for middle and high school students to increase interest in national security careers at the National Nuclear Security Administration. This work is a part of the National Security Preparedness Project (NSPP), being performed under a Department of Energy (DOE)/National Nuclear Security Administration (NNSA) grant. Previous research on the development of a properly trained and skilled national security workforce has identified a lack of interest by k-12 students in the STEM (Science, Technology, Engineering, and Mathematics) fields. Further, participation in these careers by women and minority populations is limited and is not increasing. Added to this are low educational achievement levels in New Mexico, where the marketing campaign will be deployed.

  6. Passive solar buildings research

    SciTech Connect (OSTI)

    Balcomb, J.D.

    1992-12-31T23:59:59.000Z

    This chapter covers research advances in passive solar buildings research during the time span from 1982 through 1991. These advances fall within the following categories: (1) short-term energy monitoring, (2) heat transport by natural convection within buildings, and (3) design guidelines and design tools. In short-term energy monitoring, a simulation model of the building is calibrated, based on data taken in a 3-day test. The method accurately predicts performance over an extended period. Heat transport through doorways is characterized for complex situations that arise in passive solar buildings. Simple concepts and models adequately describe the energy transport in many situations of interest. In a new approach, design guidelines are automatically generated for any specific locality. Worksheets or an accompanying computer program allow the designer to quickly and accurately evaluate performance and investigate design alternatives. 29 refs., 19 figs., 2 tabs.

  7. Passive research and practice

    SciTech Connect (OSTI)

    Balcomb, J.D.

    1983-01-01T23:59:59.000Z

    Passive-solar applications in buildings are described and examples are given to illustrate how research in the field has been approached. The major emphasis of the research has been on devising mathematical models to characterize heat flow within buildings, on the validation of these models by comparison with test results, and on the subsequent use of the models to investigate the influence of both various design parameters and the weather on system performance. Results from both test modules and monitored buildings are given. Simulation analysis, the development of simplified methods, and systems analysis are outlined. Passive-solar practice is described and the key elements that have led to successful passive-solar applications are discussed.

  8. NREL: Transportation Research - Facilities

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What's Possible for Renewable Energy: Grid IntegrationReportTransmissionResearch Cutaway image of

  9. NREL: Transportation Research - News

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What's Possible for Renewable Energy: Grid IntegrationReportTransmissionResearchNews NREL provides a

  10. NREL: Transportation Research - Projects

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What's Possible for Renewable Energy: Grid IntegrationReportTransmissionResearchNews NREL provides

  11. NREL: Transportation Research - Publications

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What's Possible for Renewable Energy: Grid IntegrationReportTransmissionResearchNews NREL

  12. Energy Research Abstracts; (USA)

    SciTech Connect (OSTI)

    Rutkowski, R.W.; Henline, D.M. (eds.)

    1991-01-01T23:59:59.000Z

    Energy Research Abstracts (ERA) provides abstracting and indexing coverage of all scientific and technical reports and patent applications originated by the US Department of Energy, its laboratories, energy centers, and contractors, as well as theses and conference papers and proceedings issued by these organizations in report form. Audiovisual materials, computer media (magnetic tapes, diskettes, etc.), and engineering drawings are included in this definition. ERA also covers other energy information prepared in report form by federal and state government organizations, foreign governments, and domestic and foreign universities and research organizations, provided that the full text of the document has been received by OSTI. Foreign report information is obtained through the International Energy Agency's fourteen nation Energy Technology Data Exchange, the International Atomic Energy Agency's International Nuclear Information System, or nation-to-nation agreements. The purpose of this publication is to announce documents produced or obtained by DOE that are not so readily available as journal articles, books, or patents. ERA does not cover nonreport literature. The scope of ERA encompasses DOE's research, development, demonstration, and technology programs resulting from its broad charter for energy sources, supplies, safety, environmental impacts, and regulation.

  13. University Coal Research | Department of Energy

    Energy Savers [EERE]

    Research University Coal Research University Coal Research Universities frequently win Fossil Energy research competitions or join with private companies to submit successful...

  14. MONTANA PALLADIUM RESEARCH INITIATIVE

    SciTech Connect (OSTI)

    Peters, John

    2012-05-09T23:59:59.000Z

    Project Objective: The overarching objective of the Montana Palladium Research Initiative is to perform scientific research on the properties and uses of palladium in the context of the U.S. Department of Energy'Ă?Â?Ă?Â?Ă?Â?Ă?Â?Ă?Â?Ă?Â?Ă?Â?Ă?Â?s Hydrogen, Fuel Cells and Infrastructure Technologies Program. The purpose of the research will be to explore possible palladium as an alternative to platinum in hydrogen-economy applications. To achieve this objective, the Initiatives activities will focus on several cutting-edge research approaches across a range of disciplines, including metallurgy, biomimetics, instrumentation development, and systems analysis. Background: Platinum-group elements (PGEs) play significant roles in processing hydrogen, an element that shows high potential to address this need in the U.S. and the world for inexpensive, reliable, clean energy. Platinum, however, is a very expensive component of current and planned systems, so less-expensive alternatives that have similar physical properties are being sought. To this end, several tasks have been defined under the rubric of the Montana Palladium Research Iniative. This broad swath of activities will allow progress on several fronts. The membrane-related activities of Task 1 employs state-of-the-art and leading-edge technologies to develop new, ceramic-substrate metallic membranes for the production of high-purity hydrogen, and develop techniques for the production of thin, defect-free platinum group element catalytic membranes for energy production and pollution control. The biomimetic work in Task 2 explores the use of substrate-attached hydrogen-producing enzymes and the encapsulation of palladium in virion-based protein coats to determine their utility for distributed hydrogen production. Task 3 work involves developing laser-induced breakdown spectroscopy (LIBS) as a real-time, in situ diagnostic technique to characterize PGEs nanoparticles for process monitoring and control. The systems engineering work in task 4 will determine how fuel cells Ă?Â?Ă?Â?Ă?Â?Ă?Â?Ă?Â?Ă?Â?Ă?Â?Ă?Â?taken as systems behave over periods of time that should show how their reformers and other subsystems deteriorate with time.

  15. RIKEN Center for Sustainable Resource Science Gene Discovery Research Group

    E-Print Network [OSTI]

    Fukai, Tomoki

    Research Team Synthetic Genomics Research Team Enzyme Research Team Bioplastic Research Team Cell Factory

  16. RIKEN Center for Sustainable Resource Science Gene Discovery Research Group

    E-Print Network [OSTI]

    Fukai, Tomoki

    Cellulose Production Research Team Synthetic Genomics Research Team Enzyme Research Team Bioplastic Research

  17. Nano Research Facility Lab Safety Manual Nano Research Facility

    E-Print Network [OSTI]

    Subramanian, Venkat

    1 Nano Research Facility Lab Safety Manual Nano Research Facility: Weining Wang Office: Brauer---chemical, biological, or radiological. Notify the lab manager, Dr. Yujie Xiong at 5-4530. Eye Contact: Promptly flush

  18. Bryant Postgraduate Research Scholarship BRYANT POSTGRADUATE RESEARCH SCHOLARSHIP REGULATIONS 2013

    E-Print Network [OSTI]

    Waikato, University of

    Bryant Postgraduate Research Scholarship 1 BRYANT POSTGRADUATE RESEARCH SCHOLARSHIP REGULATIONS 2013 BACKGROUND The D. V. Bryant Trust established Bryant Hall on land leased from the University. Since its inception, Bryant Hall has provided a supportive residential environment for first

  19. FY 91 Annual Research Plan

    SciTech Connect (OSTI)

    Not Available

    1990-12-01T23:59:59.000Z

    In line with the Federal Oil Research Program to maximize the economic producibility of the domestic oil resource, the National Institute for Petroleum and Energy Research (NIPER) presents this FY91 Annual Research Plan. NIPER is organized into two research departments -- Energy Production Research (EPR) and Fuels Research (FR). Projects in EPR deal with various aspects of enhanced oil recovery and include reservoir characterization, chemical flooding, gas injection, steam injection, microbial enhanced oil recovery, and the environmental concerns related to these processes. Projects in FR consider the impact of heavy oil and alternative fuels on the processing and end-use of fuels. Projects are briefly described.

  20. Human subjects research handbook: Protecting human research subjects. Second edition

    SciTech Connect (OSTI)

    NONE

    1996-01-30T23:59:59.000Z

    This handbook serves as a guide to understanding and implementing the Federal regulations and US DOE Orders established to protect human research subjects. Material in this handbook is directed towards new and continuing institutional review board (IRB) members, researchers, institutional administrators, DOE officials, and others who may be involved or interested in human subjects research. It offers comprehensive overview of the various requirements, procedures, and issues relating to human subject research today.

  1. Astrobiology Biogeocatalysis Research Center

    E-Print Network [OSTI]

    Maxwell, Bruce D.

    H 1 pH 2 pH 3 pH 4 pH 5 pH 6 pH 7 pH 8 pH 9 pH 10 pH 11 pH 12 pH 13 pH 14 battery acid black coffee to resemble conditions of early Earth.Yellowstone's abundant and unique thermal features give researchers; Emerald Spring, Norris Battery acid, stomach acid, black coffee, orange juice, citrus fruit, soda 2. Give

  2. Invention | GE Global Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > The Energy Materials Center at CornellOfviaInternsInvention Our

  3. Jefferson Lab: Research Highlights

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > The Energy Materials Center atdiffusivities inJLF Forms JLFJLFanNuclear

  4. Research License Agreement Template

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of ScienceandMesa del SolStrengtheningWildfiresImpurity Transport,12, 20103,University1_3355 06,Research

  5. Moving | GE Global Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > The EnergyCenterDioxide CaptureSee the Foundry's fullMonthly

  6. NETL: Onsite Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > The EnergyCenterDioxide CaptureSee theOil & Gas Efficient

  7. Pathogen Research Databases

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclear Astrophysics OneOutreachPartnershipsPartnershipsFor

  8. Powering | GE Global Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclear AstrophysicsPayroll,PhysicsPowering Whether generating or

  9. Research - Cyclotron Institute

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclear Press Releases 2014References by Websitehome /Request

  10. Research Facilities | NREL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclear Press Releases 2014References byLaboratory

  11. Research | Critical Materials Institute

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclear Press ReleasesIn the Inorganic PV thrust,

  12. Resources for Researchers | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclear Press ReleasesIn the InorganicResources

  13. Sandia Energy - Energy Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclear Press ReleasesInApplied &ClimateContactEnergyEnergy

  14. Sandia National Laboratories: Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclearHomeland and NuclearReport PartnershipsNews People

  15. Southern Research Institute Visit

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclearHomelandMultivariateSite Map Main

  16. Timeline | GE Global Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch >Internship Program The NIF andPointsThrust 1: Structure and

  17. 2004 Progress in Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch >InternshipDepartment of Energy with6, 2014, 6:32 p.m.January 200543

  18. 2005 Progress in Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch >InternshipDepartment of Energy with6, 2014, 6:32 p.m.January5

  19. Research Input Form

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Scienceand Requirements Recently ApprovedReliabilityPrincipalResearchMakingHighlightsSubmit Form

  20. Research Portfolio Map

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Scienceand Requirements RecentlyElectronic Public Reading Room Electronic PublicResearch Portfolio

  1. Research Project Description

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Scienceand Requirements RecentlyElectronic Public Reading Room Electronic PublicResearch

  2. Research | Jefferson Lab

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Scienceand Requirements RecentlyElectronic Public Reading RoomNonproliferation /Research

  3. Research News December 2014

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What's PossibleRadiation Protection Technical s oPrecipitationWeatherTacklingAbout ORNL FactResearchORD's

  4. Bisfuel links - Research centers

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625govInstrumentstdmadapInactiveVisiting the TWPSuccess Stories Site Map PrintablePresentationsProfessionalResearch

  5. THE RADIOLOGICAL RESEARCH ACCELERATOR FACILITY The Radiological Research Accelerator Facility

    E-Print Network [OSTI]

    THE RADIOLOGICAL RESEARCH ACCELERATOR FACILITY 1 The Radiological Research Accelerator Facility for Radiological Research (CRR). Using the mi- crobeam facility, 10% of the cells were irradiated through particle beam as well as the first fo- cused microbeam in the new microbeam facility. · Another significant

  6. ELSEVIER Brain Research 712 (1996) 293-298 Research report

    E-Print Network [OSTI]

    Tepper, James M.

    BRAIN RESEARCH ELSEVIER Brain Research 712 (1996) 293-298 Research report Local infusion of brain examined the effects of local infusion of BDNF on the electrophysioiogical activity of serotonergic neurons in the rat dorsal raph6 nucleus with extracellular single unit recording in vivo. Compared with vehicle-infused

  7. GENERAL RESEARCH Real Options Based Analysis of Optimal Pharmaceutical Research

    E-Print Network [OSTI]

    Maranas, Costas

    GENERAL RESEARCH Real Options Based Analysis of Optimal Pharmaceutical Research and Development optimization model (OptFolio) of pharmaceutical research and development (R&D) portfolio management using preclinical development through FDA filing and product launch.1 A drug may spend 6-10 years

  8. The Public Interest Energy Research (PIER) Lighting Research Program

    E-Print Network [OSTI]

    The Public Interest Energy Research (PIER) Lighting Research Program (LRP) needed a solid strategy. · Identify lighting codes and standards problems that require additional R&D, such as outdated lighting energy savings or demand reduction potential. They also identified additional lighting research needs

  9. Summer Program for Undergraduate Research Alaska Oregon Research Training Alliance

    E-Print Network [OSTI]

    Oregon, University of

    in SPUR Oregon-Chile International REU Program University of Oregon, Eugene OR 97403-1254 phone (541 Undergraduate Researchers in SPUR (OURS) spur.uoregon.edu Oregon-Chile International REU Program (OC-iREU) spurSummer Program for Undergraduate Research Alaska Oregon Research Training Alliance NSF REU Site

  10. Jointly Sponsored Research Program

    SciTech Connect (OSTI)

    Everett A. Sondreal; John G. Hendrikson; Thomas A. Erickson

    2009-03-31T23:59:59.000Z

    U.S. Department of Energy (DOE) Cooperative Agreement DE-FC26-98FT40321 funded through the Office of Fossil Energy and administered at the National Energy Technology Laboratory (NETL) supported the performance of a Jointly Sponsored Research Program (JSRP) at the Energy & Environmental Research Center (EERC) with a minimum 50% nonfederal cost share to assist industry in commercializing and effectively applying highly efficient, nonpolluting energy systems that meet the nation's requirements for clean fuels, chemicals, and electricity in the 21st century. The EERC in partnership with its nonfederal partners jointly performed 131 JSRP projects for which the total DOE cost share was $22,716,634 (38%) and the nonfederal share was $36,776,573 (62%). Summaries of these projects are presented in this report for six program areas: (1) resource characterization and waste management, (2) air quality assessment and control, (3) advanced power systems, (4) advanced fuel forms, (5) value-added coproducts, and (6) advanced materials. The work performed under this agreement addressed DOE goals for reductions in CO{sub 2} emissions through efficiency, capture, and sequestration; near-zero emissions from highly efficient coal-fired power plants; environmental control capabilities for SO{sub 2}, NO{sub x}, fine respirable particulate (PM{sub 2.5}), and mercury; alternative transportation fuels including liquid synfuels and hydrogen; and synergistic integration of fossil and renewable resources.

  11. Gleenglass Swarf Research

    SciTech Connect (OSTI)

    Turo, Laura A.; Skorski, Daniel C.; Schweiger, Michael J.; Ryan, Joseph V.

    2010-04-01T23:59:59.000Z

    Objective: John Sauer, Gleenglass principal, asked for research into innovative uses for a reclaimed glass slurry, also referred to as swarf. Through our research we were to determine a product and a market that could be manufactured using this fully recycled glass swarf. Background: Mr. Sauer receives the swarf from major glass manufacturers as a fine powder glass suspended in an organic dispersant and water. The swarf is produced through an industrial glass cutting process that results in the glass powder dispersed in water and recyclable glass disks; both are used in the project. Mr. Sauer's swarf studio testing has yet to produce any product with a value great enough to justify processing the swarf. Many of these limitations were believed to be due to the unknown composition and characteristics of the swarf as well as the limited lab testing ability of Mr. Sauer in his studio space. Deliverables: 1. The valuable characteristics of the swarf. 2. Products that can be produced with the swarf. 3. Market for developed products. 4. Capital investment needed to create developed product. 5. Any other applications of the swarf that were outside the scope of residential and commercial building material for use in future DOE grant proposals to the glass manufacturing facilities. 6. Additives that could change the color of the final piece to white, gray, or green.

  12. Brookhaven Graphite Research Reactor Workshop

    Broader source: Energy.gov [DOE]

    The Brookhaven Graphite Research Reactor (BGRR) was the first reactor built in the U.S. for peacetime atomic research following World War II.  Construction began in 1947 and the reactor started...

  13. 22 Research Activities 2012 Informatics

    E-Print Network [OSTI]

    Takada, Shoji

    Computer Science Computational Astrophysics Theoretical Particle Physics Cognitive Developmental Robotics Society Human Math. Astronomy Physics Robotics The Hakubi Project: Fostering Young Researchers The Hakubi researchers are employed for five years by Kyoto University as associate or assistant professors, during which

  14. DIII-D research operations

    SciTech Connect (OSTI)

    Baker, D. (ed.)

    1993-05-01T23:59:59.000Z

    This report discusses the research on the following topics: DIII-D program overview; divertor and boundary research program; advanced tokamak studies; tokamak physics; operations; program development; support services; contribution to ITER physics R D; and collaborative efforts.

  15. Catalysis Research for Energy Independence

    E-Print Network [OSTI]

    yields insights into improving the industrial catalyst for oil refining, chemicals processing into chemical fuels. In addition, we conduct applied catalysis research with industrial, academic, and other collaborate with catalysis leaders in academia, industry, and national laboratories. Research in Science

  16. Environmental research on actinide elements

    SciTech Connect (OSTI)

    Pinder, J.E. III; Alberts, J.J.; McLeod, K.W.; Schreckhise, R.G. (eds.)

    1987-08-01T23:59:59.000Z

    The papers synthesize the results of research sponsored by DOE's Office of Health and Environmental Research on the behavior of transuranic and actinide elements in the environment. Separate abstracts have been prepared for the 21 individual papers. (ACR)

  17. Sustainable Development Research Institute fonds

    E-Print Network [OSTI]

    Handy, Todd C.

    Sustainable Development Research Institute fonds Compiled by Erwin Wodarczak and Melanie Hardbattle Projects series Sous-fonds Description o "Women and Sustainable Development: Canadian Perspectives (UBC Library catalogue) #12;Fonds Description Sustainable Development Research Institute fonds. ­ 1985

  18. Title: Postdoctoral Research Employment Type: Administrative Professional

    E-Print Network [OSTI]

    , and facilities for genomics, preoteomics, and transgenic animal research. The hard work of research is balanced

  19. Research Administration Index of Commonly Used Acronyms

    E-Print Network [OSTI]

    Salama, Khaled

    /Property System Review CRADA Cooperative Research and Development Agreement CRS Congressional Research Service CSR

  20. Argonne Researchers | Argonne National Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Researchers Name Topic - Any - General Argonne Information -Awards -Honors Energy -Energy efficiency --Vehicles ---Alternative fuels ---Automotive engineering ---Biofuels...