National Library of Energy BETA

Sample records for location telephone cellular

  1. CELLULAR TELEPHONE FACILITIES A White Paper

    E-Print Network [OSTI]

    California at Santa Barbara, University of

    1 CELLULAR TELEPHONE FACILITIES ON CAMPUS A White Paper May 1, 2003 #12;2 TABLE OF CONTENTS Background on Cellular Telephones.......................................................... 5 History of Cellular Telephone Sites on Campus.............................................. 7 Current Terms

  2. Cellular telephone-based radiation detection instrument

    DOE Patents [OSTI]

    Craig, William W. (Pittsburg, CA); Labov, Simon E. (Berkeley, CA)

    2011-06-14

    A network of radiation detection instruments, each having a small solid state radiation sensor module integrated into a cellular phone for providing radiation detection data and analysis directly to a user. The sensor module includes a solid-state crystal bonded to an ASIC readout providing a low cost, low power, light weight compact instrument to detect and measure radiation energies in the local ambient radiation field. In particular, the photon energy, time of event, and location of the detection instrument at the time of detection is recorded for real time transmission to a central data collection/analysis system. The collected data from the entire network of radiation detection instruments are combined by intelligent correlation/analysis algorithms which map the background radiation and detect, identify and track radiation anomalies in the region.

  3. Cellular telephone-based wide-area radiation detection network

    DOE Patents [OSTI]

    Craig, William W. (Pittsburg, CA); Labov, Simon E. (Berkeley, CA)

    2009-06-09

    A network of radiation detection instruments, each having a small solid state radiation sensor module integrated into a cellular phone for providing radiation detection data and analysis directly to a user. The sensor module includes a solid-state crystal bonded to an ASIC readout providing a low cost, low power, light weight compact instrument to detect and measure radiation energies in the local ambient radiation field. In particular, the photon energy, time of event, and location of the detection instrument at the time of detection is recorded for real time transmission to a central data collection/analysis system. The collected data from the entire network of radiation detection instruments are combined by intelligent correlation/analysis algorithms which map the background radiation and detect, identify and track radiation anomalies in the region.

  4. Cellular telephone-based radiation sensor and wide-area detection network

    DOE Patents [OSTI]

    Craig, William W. (Pittsburg, CA); Labov, Simon E. (Berkeley, CA)

    2006-12-12

    A network of radiation detection instruments, each having a small solid state radiation sensor module integrated into a cellular phone for providing radiation detection data and analysis directly to a user. The sensor module includes a solid-state crystal bonded to an ASIC readout providing a low cost, low power, light weight compact instrument to detect and measure radiation energies in the local ambient radiation field. In particular, the photon energy, time of event, and location of the detection instrument at the time of detection is recorded for real time transmission to a central data collection/analysis system. The collected data from the entire network of radiation detection instruments are combined by intelligent correlation/analysis algorithms which map the background radiation and detect, identify and track radiation anomalies in the region.

  5. Evolving Cellular Automata for Location Management in Mobile Computing Networks

    E-Print Network [OSTI]

    Ha, Dong S.

    entering one of these reporting cells. To create such an evolving CA system, cells in the network for a number of test problems. Index Terms--Cellular automata, genetic algorithms, mobile computing, mobility to interferences. On the other hand, a miss on the location of a mobile terminal will necessitate a search

  6. Your T7316 telephone Mute button

    E-Print Network [OSTI]

    Your T7316 telephone © Mute button Turns the microphone off or on when you are on a call. ¬ Headset display Shows the time and date, call and feature information. Display buttons The label for display label D E F Wall mount with a telephone stand Mount the telephone onto the screws and slide it down

  7. Your T7208 telephone Mute button

    E-Print Network [OSTI]

    Your T7208 telephone © Mute button Turns the microphone off or on when you are on a call. ¬ Headset. Press when finished. Use the button label strip on the telephone to show what is programmed on the buttons. Spare button label strips are provided with your telephone. How to label your buttons 1. Remove

  8. The Telephone: An Invention with Many Fathers

    ScienceCinema (OSTI)

    Brenni, Paolo [CNR-FST-IMSS, Florence, Italy

    2010-01-08

    The names of A.G. Bell, A. Meucci, P.Reis, E. Gray, just to mention the most important ones, are all connected with the invention of the telephone. Today, the Italian inventor A. Meucci is recognized as being the first to propose a working prototype of the electric telephone. However, for a series of reasons his strenuous efforts were not rewarded. I will not repeat here the endless and complex disputes about the ?real father? of the telephone. From an historical point of view it is more interesting to understand why so many individuals from different backgrounds conceived of a similar apparatus and why most of these devices were simply forgotten or just remained laboratory curiosities. The case of the development of the telephone is an emblematic and useful example for better understanding the intricate factors which are involved in the birth of an invention and reasons for its success and failure.

  9. Community Cellular Networks

    E-Print Network [OSTI]

    Heimerl, Kurtis

    2013-01-01

    2.1.3 Rural Cellular . . . . . . . . . . . . . . 2.2Community Cellular . . . . . . . . . . . . . . . . .9.1.1Community Cellular Networks 3.1 De?ning Community Cellular

  10. CALIFORNIA LAWRENCE BERKELEY LAB POC David Chen Telephone

    Energy Savers [EERE]

    LAWRENCE BERKELEY LAB POC David Chen Telephone (510) 486-4506 Email dtchen@lbl.gov Engineering Services 541330 Drafting Services 541340 Geophysical Surveying and Mapping Services...

  11. Fibre based cellular transfection

    E-Print Network [OSTI]

    2008-01-01

    and K. Dholakia, "Femtosecond cellular transfection using aFibre based cellular transfection X. Tsampoula 1 *, K.parameters for successful cellular transfection. We readily

  12. Energy Savings by Wideband Temperature Control in Telephone Offices 

    E-Print Network [OSTI]

    Lingousky, J. E.; McKay, J. R.

    1983-01-01

    In 1982, 6.9 million BOE of energy costing nearly $600 million was used in approximately 16,000 Bell System Telephone equipment buildings. About 27% of that energy was used for heating, ventilating and air conditioning. ...

  13. Origins of cellular geometry

    E-Print Network [OSTI]

    Marshall, Wallace F

    2011-01-01

    as: Marshall WF: Origins of cellular geometry. BMC Biologyin the author’s lab on cellular geometry is supported by NIHOpen Access Origins of cellular geometry Wallace F Marshall*

  14. Modulating cellular fate with arrayed cellular microenvironment technology

    E-Print Network [OSTI]

    Shah, Kevan Dinesh

    2009-01-01

    A.D. and C.O. Pabo, Cellular uptake of the tat protein frommatrix microarray for probing cellular differentiation. Natcells with arrayed cellular microenvironment technology.

  15. IRS-Impersonation SCAMS IRS-Impersonation Telephone Scam

    E-Print Network [OSTI]

    Dennett, Daniel

    making the rounds throughout the country. Callers claim to be employees of the IRS, but are not directory (http://whitepages.tufts.edu) as the fraudulent caller appears to be obtaining mobile phone numbers from this directory. This may help reduce your exposure to telephone scams and other unwanted

  16. Stratified random sampling plan for an irrigation customer telephone survey

    SciTech Connect (OSTI)

    Johnston, J.W.; Davis, L.J.

    1986-05-01

    This report describes the procedures used to design and select a sample for a telephone survey of individuals who use electricity in irrigating agricultural cropland in the Pacific Northwest. The survey is intended to gather information on the irrigated agricultural sector that will be useful for conservation assessment, load forecasting, rate design, and other regional power planning activities.

  17. Financial Policy Manual 2360 TRAVEL AND ENTERTAINMENT POLICY TELEPHONE USAGE

    E-Print Network [OSTI]

    George, Edward I.

    Financial Policy Manual Page 1 2360 ­ TRAVEL AND ENTERTAINMENT POLICY ­ TELEPHONE USAGE Resp expenses incurred when traveling on behalf of the University. SCOPE This policy applies responsibilities of the employee, student or postdoc can be found in Policy #2352. RESPONSIBILITY OF APPROVERS

  18. EMERGENCY PREPAREDNESS INFORMATION FOR MTL Important Telephone Numbers

    E-Print Network [OSTI]

    Reif, Rafael

    EMERGENCY PREPAREDNESS INFORMATION FOR MTL Important Telephone Numbers Dial 100 from a campus land Emergencies Alternatively dial 617 253-1212 for an ambulance or emergency assistance Dial 617- 253-open 24/7) for a non-emergency medical issue: 617- 253-1311 Dial 617-452-3477 for the EHS office

  19. Telephone enquires +44 (0)20 7040 8095

    E-Print Network [OSTI]

    Weyde, Tillman

    strategy and policy · Transport energy and emissions · Management and leadership Electives · OptimisationTelephone enquires +44 (0)20 7040 8095 Find out more, visit www.city.ac.uk/transport-msc Email enquiries pgtransport@city.ac.uk Academic excellence for business and the professions Transport Systems

  20. CELLULAR PHYSIOLOGY Master's Thesis

    E-Print Network [OSTI]

    Kersting, Roland

    CELLULAR PHYSIOLOGY Master's Thesis Our research group comprises young group leaders, postdocs, Ph techniques. · High-resolution fluorescence imaging on cellular model systems. Contact: Prof. Claudia Veigel-Maximilians-Universit¨at M¨unchen Chair of Cellular Physiology Schillerstr. 44 80336 M¨unchen www

  1. Cellular Automata Jarkko Kari

    E-Print Network [OSTI]

    Kari, Jarkko

    Cellular Automata Jarkko Kari Spring 2013 University of Turku #12;1 Preliminaries 1.1 Introduction A cellular automaton is a discrete dynamical system that consists of a regular network of finite state. Cellular automata are · discrete in both space and time, · homogeneous in space and time (same update rule

  2. Cellular neurothekeoma with neuroendocrine differentiation

    E-Print Network [OSTI]

    D'Antonio, Antonio; Cuomo, Roberto; Angrisani, Basilio; Addesso, Maria; Angrisani, Pasquale

    2011-01-01

    Satoh T, Narisawa Y. Cellular neurothekeoma with histiocyticKj, Moon KC, Koh JK. Cellular neurothekeoma with possibleClinical pathologic challenge. Cellular neurothekeoma. Am J

  3. Cellular Mechanobiology of Glioblastoma Multiforme

    E-Print Network [OSTI]

    Ulrich, Theresa Ann

    2011-01-01

    cancer cell growth and cellular phenotype. PLoS ONE 2010; 5:offer resistance to cellular contractile forces. However,contractile mechanics. Cellular and Molecular Bioengineering

  4. Alaska Power and Telephone Co | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION JEnvironmental Jump to:EAand DaltonSolarOpen5 -Telephone Co Jump to: navigation, search Name:

  5. Alaska Power and Telephone Co | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION JEnvironmental Jump to:EAand DaltonSolarOpen5 -Telephone Co Jump to: navigation, search Name:and

  6. Telephoning for Energy Efficiency in Vermont | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious RankADVANCEDInstallers/ContractorsPhotovoltaics »Tankless WaterEnergyJanuary28-982ThisTelephoning for Energy

  7. Cellular Mechanotransduction via Microfabricated Post Arrays

    E-Print Network [OSTI]

    Higa, Adrienne

    2012-01-01

    Glycosphingolipids in cellular interaction, differentiation,the architectural basis of cellular mechanotransduction. ,”Unidirectional mechanical cellular stimuli via micropost

  8. Cellular and Molecular Bioengineering

    E-Print Network [OSTI]

    1 23 Cellular and Molecular Bioengineering ISSN 1865-5025 Volume 6 Number 1 Cel. Mol. Bioeng. (2013,2 and ANATOLY B. KOLOMEISKY 2 1 Department of Bioengineering, Rice University, Houston, TX 77005, USA; and 2

  9. Quantum Cellular Automata

    E-Print Network [OSTI]

    K. Wiesner

    2008-08-05

    Quantum cellular automata (QCA) are reviewed, including early and more recent proposals. QCA are a generalization of (classical) cellular automata (CA) and in particular of reversible CA. The latter are reviewed shortly. An overview is given over early attempts by various authors to define one-dimensional QCA. These turned out to have serious shortcomings which are discussed as well. Various proposals subsequently put forward by a number of authors for a general definition of one- and higher-dimensional QCA are reviewed and their properties such as universality and reversibility are discussed.

  10. Quantization of Cellular Automata

    E-Print Network [OSTI]

    Pablo Arrighi; Vincent Nesme

    2009-03-02

    Take a cellular automaton, consider that each configuration is a basis vector in some vector space, and linearize the global evolution function. If lucky, the r esult could actually make sense physically, as a valid quantum evolution; but do es it make sense as a quantum cellular automaton? That is the main question we a ddress in this paper. In every model with discrete time and space, two things ar e required in order to qualify as a cellular automaton: invariance by translatio n and locality. We prove that this locality condition is so restrictive in the q uantum case that every quantum cellular automaton constructed in this way - i. e., by linearization of a classical one - must be reversible. We also discuss some subtleties about the extent of nonlocality that can be encountered in the o ne-dimensional case; we show that, even when the quantized version is non local, still, under some conditions, we may be unable to use this nonlocality to trans mit information nonlocally.

  11. Freezing Cellular Automata Bootstrap Percolation

    E-Print Network [OSTI]

    Theyssier, Guillaume

    Freezing Cellular Automata and Bootstrap Percolation UAI - Doctorado en Ingenería de Sistemas-nilpotency is a simpler problem (0 2) in the simply convergent case #12;#12;Freezing cellular automata #12;Freezing cellular automata Q = {0, . . . , n - 1} with natural order N arbitrary neighborhood F is freezing if x, z

  12. Cellular and vaccine therapeutic approaches for gliomas

    E-Print Network [OSTI]

    2010-01-01

    cell vaccination and cellular immunotherapy using anti-CD3article as: Hickey et al. : Cellular and vaccine therapeuticREVIEW Open Access Cellular and vaccine therapeutic

  13. Sclerosing cellular blue nevus simulating melanoma

    E-Print Network [OSTI]

    Aydingoz, Ikbal Esen; Dikicioglu-Cetin, Emel

    2012-01-01

    Sclerosing cellular blue nevus simulating melanoma Ikbal48-year-old female with sclerosing cellular blue nevus withwas unusual for a sclerosing cellular blue nevus. Besides

  14. Cellular Mechanisms Underlying Retinal Wave Generation

    E-Print Network [OSTI]

    Ford, Kevin

    2011-01-01

    assembled by short-range cellular interactions. J Neurosci,II. III. Cellular mechanisms underlying cholinergic retinalL. Felix, Marla B. Feller. Cellular Mechanisms underlying

  15. SCHOOL OF DENTISTRY TELEPHONE DIRECTORY Administration Phone Room Human Resources Phone Room

    E-Print Network [OSTI]

    Minnesota, University of

    SCHOOL OF DENTISTRY TELEPHONE DIRECTORY Administration Phone Room Human Resources Phone Room Leon Employee Administrative Support 5-5751 15-136 Janet Campanaro Administrative Support, PASS 5-6950 15

  16. Weather and emotional state: a search for associations between weather and calls to telephone counseling services 

    E-Print Network [OSTI]

    Stillman, Daniel Noah

    2000-01-01

    Calls to four telephone counseling services, or "hotlines", each serving communities in a major metropolitan area of the United States (Detroit, Washington DC, Dallas and Seattle), were analyzed for influence from daily weather. Associations...

  17. Consensual Listening-in to or Recording Telephone/Radio Conversations (restricted)

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1992-11-12

    This Order specifies the Department of Energy (DOE) policy regarding the consensual listening-in to or recording of conversations on radio and telephone systems. Canceled by DOE N 251.107.

  18. Cellular automata on Cayley tree

    E-Print Network [OSTI]

    Hasan Akin

    2012-11-30

    In this paper, we study cellular automata on Cayley tree of order 2 over the field $\\mathbb Z_p$ (the set of prime numbers modulo $p$). We construct the rule matrix corresponding to finite cellular automata on Cayley tree. Further, we analyze the reversibility problem of this cellular automata for some given values of $a,b,c,d\\in \\mathbb{Z}_{p}\\setminus {0}$ and the levels $n$ of Cayley tree. We compute the measure-theoretical entropy of the cellular automata which we define on Cayley tree.

  19. Library Locations Locations other than Main Library

    E-Print Network [OSTI]

    Library Locations Locations other than Main Library Example: Feminist Studies HQ1410 .U54 2009 ............................................................2 Central Call Number Main Library Location Main Library Example: Main Library HQ1410 .U54 2009 See Center (ATC) Classroom 1575 Building Operations Main Entrance Map and Imagery Laboratory (MIL

  20. Library Locations Locations other than Main Library

    E-Print Network [OSTI]

    Library Locations Locations other than Main Library Example: Feminist Studies HQ1410 .U54 2009 these from the library catalog: www.library.ucsb.edu/depts/access/howinprocess.html Main: Items located in the Main Library, Davidson Main Serials Reading Area: 2 North Map & Imagery Lab: 1 North Media Collection

  1. IEEE Wireless Communications April 200710 1536-1284/07/$20.00 2007 IEEE Cellular device

    E-Print Network [OSTI]

    Haas, Zygmunt J.

    IEEE Wireless Communications · April 200710 1536-1284/07/$20.00 © 2007 IEEE AP Cellular device Cellular RAN BS HSS: Home subscriber HLR: Home location register FUTURE CONVERGED WIRELESS AND MOBILITY PLATFORM INTRODUCTION The ever-increasing demand of users for various wireless communication services has

  2. Locative Inversion In Cantonese

    E-Print Network [OSTI]

    Mok, Sui-Sang

    1992-01-01

    This paper proposes that locative inversion is a widespread syntactic process in Cantonese. The sentence-initial locative phrases in the Locative Inversion sentences are argued to be subjects which come from the postverbal complement position...

  3. Algebraic Cellular Automata and Groups Michel Coornaert

    E-Print Network [OSTI]

    Delzant, Thomas

    Algebraic Cellular Automata and Groups Michel Coornaert IRMA, Strasbourg, France International Cellular Automata and Groups March 7, 2011 1 / 25 #12;Algebraic Cellular Automata and Groups Michel, On algebraic cellular automata, arXiv:1011.4759. Michel Coornaert (IRMA, Strasbourg, France) Algebraic Cellular

  4. Captive Cellular Automata MFCS 2004, Praha

    E-Print Network [OSTI]

    Theyssier, Guillaume

    Captive Cellular Automata MFCS 2004, Praha Guillaume Theyssier (LIP, ENS Lyon, France) #12;Introduction -- (1) 2 Captive Cellular Automata Central issue in cellular automata (CA) theory: local definition ? - global dynamics #12;Introduction -- (1) 2 Captive Cellular Automata Central issue in cellular

  5. Accommodation Location(s) Cologne -Ehrenfeld.

    E-Print Network [OSTI]

    Molinari, Marc

    Accommodation Location(s) ­ Cologne - Ehrenfeld. Price of rent ­ Sub-let, cost roughly 300 euros a month inc bills. Organisation of accommodation/gas/electricity/internet/phones ­ Because I lived with Telekom for phone/internet as they just try to rip you off! Germany COLOGNE Language Assistantship Travel

  6. Programmable Cellular Logic: Past, Present, and Future

    E-Print Network [OSTI]

    Tessier, Russell

    Programmable Cellular Logic: Past, Present, and Future Russell Tessier \\Lambda Laboratory changes in technology and architectural trends as they pertain to cellular arrays since the 1960's. Direct comparisons of various cellular array architectural features with contemporary programmable logic features

  7. Emergence of cellularity Friederike Mller

    E-Print Network [OSTI]

    Kersting, Roland

    Outlook #12;Osmosis Diffusion through a semipermeable membrane driven by a concentration gradient Solvent Further Experiments Evolution Outlook #12;· Energy Storage · Membrane growth induces pH-gradient advantage Driving the evolution of metabolism? Simple physicochemical properties Essential cellular

  8. Two Experiments Comparing Reading with Listening for Human Processing of Conversational Telephone Speech

    E-Print Network [OSTI]

    Two Experiments Comparing Reading with Listening for Human Processing of Conversational Telephone of no experiment that directly compares Switchboard and Fishertype CTS transcripts with audio in terms of human. Abstract We report on results of two experiments designed to compare subjects' ability to extract

  9. Princeton University Vice President and Secretary Telephone: 609-258-6428

    E-Print Network [OSTI]

    Bou-Zeid, Elie

    Princeton University Vice President and Secretary Telephone: 609-258-6428 One Nassau Hall, light, and materials. He is the recipient of the 2002 American Academy of Arts and letters Award, Princeton, New Jersey 08544 Email: durkee@princeton.edu February 2, 2012 To: Members of the Planning Board

  10. MOBILE DEVICE LOCATION INFORMATION ACQUISITION FRAMEWORK FOR DEVELOPMENT OF LOCATION

    E-Print Network [OSTI]

    Dustdar, Schahram

    MOBILE DEVICE LOCATION INFORMATION ACQUISITION FRAMEWORK FOR DEVELOPMENT OF LOCATION INFORMATION, 1040 Vienna, Austria dustdar@infosys.tuwien.ac.at Keywords: Mobile device location information, location information based services, location information acquisition. Abstract: Mobile device location

  11. Optimal fault location 

    E-Print Network [OSTI]

    Knezev, Maja

    2008-10-10

    sequence of events newly obtained recording belongs. Software prototype of the proposed automated fault location analysis is developed using Java programming language. Fault location analysis is automatically triggered by appearance of new event files in a...

  12. Cellular automorphisms and self duality Lowell Abrams

    E-Print Network [OSTI]

    Slilaty, Daniel

    Cellular automorphisms and self duality Lowell Abrams and Daniel Slilaty August 3, 2013 Dedicated cellular automorphisms of the sphere, projective plane, torus, Klein bottle, and three-crosscaps (Dyck irreducible cellular automorphisms in S. 1 Introduction 2 2 Cellular automorphisms 5 2.1 Graph basics

  13. Cellular automorphisms and self duality Lowell Abrams

    E-Print Network [OSTI]

    Abrams, Lowell

    Cellular automorphisms and self duality Lowell Abrams and Daniel Slilaty August 8, 2012 Dedicated cellular automorphisms of the sphere, projective plane, torus, Klein bottle, and three-crosscaps (Dyck irreducible cellular automorphisms in S. 1 Introduction 2 2 Cellular automorphisms 5 2.1 Graph basics

  14. From seconds to months: multi-scale dynamics of mobile telephone calls

    E-Print Network [OSTI]

    Saramaki, Jari

    2015-01-01

    Big Data on electronic records of social interactions allow approaching human behaviour and sociality from a quantitative point of view with unforeseen statistical power. Mobile telephone Call Detail Records (CDRs), automatically collected by telecom operators for billing purposes, have proven especially fruitful for understanding one-to-one communication patterns as well as the dynamics of social networks that are reflected in such patterns. We present an overview of empirical results on the multi-scale dynamics of social dynamics and networks inferred from mobile telephone calls. We begin with the shortest timescales and fastest dynamics, such as burstiness of call sequences between individuals, and "zoom out" towards longer temporal and larger structural scales, from temporal motifs formed by correlated calls between multiple individuals to long-term dynamics of social groups. We conclude this overview with a future outlook.

  15. Reversible micromachining locator

    DOE Patents [OSTI]

    Salzer, L.J.; Foreman, L.R.

    1999-08-31

    This invention provides a device which includes a locator, a kinematic mount positioned on a conventional tooling machine, a part carrier disposed on the locator and a retainer ring. The locator has disposed therein a plurality of steel balls, placed in an equidistant position circumferentially around the locator. The kinematic mount includes a plurality of magnets which are in registry with the steel balls on the locator. In operation, a blank part to be machined is placed between a surface of a locator and the retainer ring (fitting within the part carrier). When the locator (with a blank part to be machined) is coupled to the kinematic mount, the part is thus exposed for the desired machining process. Because the locator is removably attachable to the kinematic mount, it can easily be removed from the mount, reversed, and reinserted onto the mount for additional machining. Further, the locator can likewise be removed from the mount and placed onto another tooling machine having a properly aligned kinematic mount. Because of the unique design and use of magnetic forces of the present invention, positioning errors of less than 0.25 micrometer for each machining process can be achieved. 7 figs.

  16. Cellular/Molecular Current versus Ca2

    E-Print Network [OSTI]

    Cellular/Molecular Ca2 Current versus Ca2 Channel Cooperativity of Exocytosis Victor Matveev,1 into this question by probing the sensitivity of exocytosis to Ca2 influx. While varying extra- cellular

  17. CELLULAR GEOGRAPHY1 W. R. TOBLER2

    E-Print Network [OSTI]

    Tobler, Waldo

    CELLULAR GEOGRAPHY1 W. R. TOBLER2 Captain Ahab, in the film version of Moby Dick, searches realistic variable- number-of-neighbors case but the insight is more easily gained in the cellular case. I

  18. Introducing freezing cellular automata Taller @ Concepcin

    E-Print Network [OSTI]

    Theyssier, Guillaume

    Introducing freezing cellular automata Taller @ Concepción G. Theyssier (CNRS, CMM) October, 2013;#12;Freezing cellular automata Q = {0, . . . , n - 1} with natural order N arbitrary neighborhood F is freezing if x, z : F(x)z xz #12;Freezing cellular automata Q = {0, . . . , n - 1} with natural order N

  19. Programmable Cellular Logic: Past, Present, and Future

    E-Print Network [OSTI]

    Tessier, Russell

    Programmable Cellular Logic: Past, Present, and Future Russell Tessier Laboratory for Computer in technology and architectural trends as they pertain to cellular arrays since the 1960's. Direct comparisons of various cellular array architectural features with contemporary programmable logic features are made

  20. Cellular Automata: Basic Intro Professor Leigh Tesfatsion

    E-Print Network [OSTI]

    Tesfatsion, Leigh

    Cellular Automata: Basic Intro Professor Leigh Tesfatsion Economics Dept., Iowa State University What are Cellular Automata (CA)? Illustrative Examples: · John Conway's Game of Life · Schelling (2005), and Prof. Lars-Erik Cederman (2005). #12;What are Cellular Automata? #12;Illustrations of Simple

  1. Almost cellular algebras Nicolas Guay, Stewart Wilcox

    E-Print Network [OSTI]

    Guay, Nicolas

    Almost cellular algebras Nicolas Guay, Stewart Wilcox Abstract We obtain results on algebras which have many of the properties of cellular algebras except for the existence of a certain anti-involution. We show that they are applicable to q-walled Brauer-Clifford superalgebras. Introduction Cellular

  2. Advanced Review Viruses and the cellular RNA

    E-Print Network [OSTI]

    Advanced Review Viruses and the cellular RNA decay machinery Marta Maria Gaglia and Britt A. Glaunsinger The ability to control cellular and viral gene expression, either globally or selectively evolve and fine- tune mechanisms to exploit the cellular machinery for their own replication, while

  3. CELLULAR ALGEBRAS: INFLATIONS AND MORITA EQUIVALENCES

    E-Print Network [OSTI]

    Xi, Changchang

    CELLULAR ALGEBRAS: INFLATIONS AND MORITA EQUIVALENCES STEFFEN KO$ NIG AND CHANGCHANG XI Dedicated to Professor Helmut Lenzing on the occasion of his 60th birthday 1. Introduction Cellular algebras have make explicit an inductive construction of cellular algebras which has as input data of linear algebra

  4. Cellular asymmetry and individuality in directional sensing

    E-Print Network [OSTI]

    van Oudenaarden, Alexander

    Cellular asymmetry and individuality in directional sensing Azadeh Samadani, Jerome Mettetal, it is becoming increasingly clear that, even in a genetically identical population, cellular behavior can vary signals (cellular asymmetry). Second, we find that the magnitude of this asymmetry varies greatly among

  5. Cellular algebras and Cartan matrices Changchang Xi

    E-Print Network [OSTI]

    Xi, Changchang

    Cellular algebras and Cartan matrices by Changchang Xi Department of Mathematics, Beijing Normal rational numbers do not imply the semi­simplicity of A. However, we prove that a cellular algebra matrices to classify the cellular algebras with the property that the determinant of the Cartan matrix

  6. Joint Adaptive Rate and Scheduling in Cellular Wireless Networks

    E-Print Network [OSTI]

    Chang, Hung-Bin

    2015-01-01

    Aided Failover for Multicast Scheduling in Wireless CellularVideo Multicast for Multi-cell Cellular Wireless Net-and Uplink Fractional Frequency Reuse in Cellular Wireless

  7. Molecular Recognition by Synthetic Receptors in Biomimetic and Cellular Systems

    E-Print Network [OSTI]

    Ghang, Yoo-Jin

    2015-01-01

    Synthetic Glycopolymers into Cellular Membranes. ” J. Am.between siRNA Localization, Cellular Uptake, and RNAi inas an Anti-Tumor Drig: Cellular Mechanisms of Activity, Drug

  8. Role of cellular microenvironment in non-viral gene transfer

    E-Print Network [OSTI]

    Dhaliwal, Anandika

    2012-01-01

    medicine. Journal of cellular physiology 213: 341-347. Chen,engineering. Journal of cellular and molecular medicine 11:oligonucleotides. Molecular and cellular neurosciences 7:

  9. Location linked information

    E-Print Network [OSTI]

    Mankins, Matthew William David, 1975-

    2003-01-01

    This work builds an infrastructure called Location Linked Information that offers a means to associate digital information with public, physical places. This connection creates a hybrid virtual/physical space, called glean ...

  10. Locating Heat Recovery Opportunities 

    E-Print Network [OSTI]

    Waterland, A. F.

    1981-01-01

    Basic concepts of heat recovery are defined as they apply to the industrial community. Methods for locating, ranking, and developing heat recovery opportunities are presented and explained. The needs for useful heat 'sinks' are emphasized as equal...

  11. Quantum Cellular Automata Without Particles

    E-Print Network [OSTI]

    David A. Meyer; Asif Shakeel

    2015-06-04

    Quantum Cellular Automata (QCA) constitute a natural discrete model for quantum field theory (QFT). Although QFTs are defined without reference to particles, computations are done in terms of Feynman diagrams, which are explicitly interpreted in terms of interacting particles. Similarly, the easiest QCA to construct are Quantum Lattice Gas Automata (QLGA). A natural question then is, "are all nontrivial QCA QLGA?". Here we show by construction that the answer is "no"; thus there are QCA, even in $1+1$ dimensions, that have no particle interpretation.

  12. The effect of congestion location on motorists' propensity to divert in response to real-time information 

    E-Print Network [OSTI]

    Jeyapaul, Anand

    1992-01-01

    to Real-Time Information. (December 1992) Anand Jeyapaul, B. Tech. , Indian Institute of Technology Chair of Advisory Committee: Dr. Conrad L. Dudek A work-based telephone survey of commuters in Dallas was done primarily to study if the motorists... such as age, sex, average travel time, and importance of arriving at work on time. Using the survey, motorist time savings values were obtained for four hypothetical radio traffic advisory messages, designed to vary alternative route and congestion location...

  13. Cellular structures on Hecke algebras Cedric Bonnafe

    E-Print Network [OSTI]

    Bonnafé, Cédric

    Cellular structures on Hecke algebras of type B C´edric Bonnaf´e CNRS (UMR 6623) - Universit´e de Franche-Comt´e (Besan¸con) Sydney, June 2007 C´edric Bonnaf´e (CNRS, Besan¸con, France) Cellular, decomposition map C´edric Bonnaf´e (CNRS, Besan¸con, France) Cellular structures Sydney, June 2007 2 / 25 #12

  14. Discrete geodesics and cellular automata

    E-Print Network [OSTI]

    Pablo Arrighi; Gilles Dowek

    2015-07-24

    This paper proposes a dynamical notion of discrete geodesics, understood as straightest trajectories in discretized curved spacetime. The notion is generic, as it is formulated in terms of a general deviation function, but readily specializes to metric spaces such as discretized pseudo-riemannian manifolds. It is effective: an algorithm for computing these geodesics naturally follows, which allows numerical validation---as shown by computing the perihelion shift of a Mercury-like planet. It is consistent, in the continuum limit, with the standard notion of timelike geodesics in a pseudo-riemannian manifold. Whether the algorithm fits within the framework of cellular automata is discussed at length. KEYWORDS: Discrete connection, parallel transport, general relativity, Regge calculus.

  15. Discrete geodesics and cellular automata

    E-Print Network [OSTI]

    Arrighi, Pablo

    2015-01-01

    This paper proposes a dynamical notion of discrete geodesics, understood as straightest trajectories in discretized curved spacetime. The notion is generic, as it is formulated in terms of a general deviation function, but readily specializes to metric spaces such as discretized pseudo-riemannian manifolds. It is effective: an algorithm for computing these geodesics naturally follows, which allows numerical validation---as shown by computing the perihelion shift of a Mercury-like planet. It is consistent, in the continuum limit, with the standard notion of timelike geodesics in a pseudo-riemannian manifold. Whether the algorithm fits within the framework of cellular automata is discussed at length. KEYWORDS: Discrete connection, parallel transport, general relativity, Regge calculus.

  16. Fundamental Limits to Cellular Sensing

    E-Print Network [OSTI]

    Pieter Rein ten Wolde; Nils B. Becker; Thomas E. Ouldridge; A. Mugler

    2015-05-25

    In recent years experiments have demonstrated that living cells can measure low chemical concentrations with high precision, and much progress has been made in understanding what sets the fundamental limit to the precision of chemical sensing. Chemical concentration measurements start with the binding of ligand molecules to receptor proteins, which is an inherently noisy process, especially at low concentrations. The signaling networks that transmit the information on the ligand concentration from the receptors into the cell have to filter this noise extrinsic to the cell as much as possible. These networks, however, are also stochastic in nature, which means that they will also add noise to the transmitted signal. In this review, we will first discuss how the diffusive transport and binding of ligand to the receptor sets the receptor correlation time, and then how downstream signaling pathways integrate the noise in the receptor state; we will discuss how the number of receptors, the receptor correlation time, and the effective integration time together set a fundamental limit on the precision of sensing. We then discuss how cells can remove the receptor noise while simultaneously suppressing the intrinsic noise in the signaling network. We describe why this mechanism of time integration requires three classes of resources---receptors and their integration time, readout molecules, energy---and how each resource class sets a fundamental sensing limit. We also briefly discuss the scheme of maximum-likelihood estimation, the role of receptor cooperativity, and how cellular copy protocols differ from canonical copy protocols typically considered in the computational literature, explaining why cellular sensing systems can never reach the Landauer limit on the optimal trade-off between accuracy and energetic cost.

  17. Electric current locator

    DOE Patents [OSTI]

    King, Paul E. (Corvallis, OR); Woodside, Charles Rigel (Corvallis, OR)

    2012-02-07

    The disclosure herein provides an apparatus for location of a quantity of current vectors in an electrical device, where the current vector has a known direction and a known relative magnitude to an input current supplied to the electrical device. Mathematical constants used in Biot-Savart superposition equations are determined for the electrical device, the orientation of the apparatus, and relative magnitude of the current vector and the input current, and the apparatus utilizes magnetic field sensors oriented to a sensing plane to provide current vector location based on the solution of the Biot-Savart superposition equations. Description of required orientations between the apparatus and the electrical device are disclosed and various methods of determining the mathematical constants are presented.

  18. Final Exam Location and Time

    E-Print Network [OSTI]

    Final Exam Location and Time. Math 162 Fall 2001. Date: Wednesday December 12, 2001. Time: 7:00 pm -9:00 pm. Location: Lambert Fieldhouse ...

  19. Final Exam Location and Time

    E-Print Network [OSTI]

    Final Exam Location and Time. Math 161 Fall 2001. Date: Friday December 14, 2001. Time: 8:00 am -10:00 am. Location: Lambert Fieldhouse ...

  20. Experimental demonstration of clocked single-electron switching in quantum-dot cellular automata

    E-Print Network [OSTI]

    Orlov, Alexei

    tunnel junctions where the location of an excess electron is defined by electrostatic potentials on gates, the electrons remain trapped on the dots regardless of the state of the input signal. Although semiconductorExperimental demonstration of clocked single-electron switching in quantum-dot cellular automata

  1. Energy-Efficient Transmission Schemes in Cooperative Cellular Systems

    E-Print Network [OSTI]

    Yang, Wei; Wang, Ying; Sun, Wanlu

    2010-01-01

    Energy-efficient communication is an important requirement for mobile devices, as the battery technology has not kept up with the growing requirements stemming from ubiquitous multimedia applications. This paper considers energy-efficient transmission schemes in cooperative cellular systems with unbalanced traffic between uplink and downlink. Theoretically, we derive the optimal transmission data rate, which minimizes the total energy consumption of battery-powered terminals per information bit. The energy-efficient cooperation regions are then investigated to illustrate the effects of relay locations on the energy-efficiency of the systems, and the optimal relay location is found for maximum energy-efficiency. Finally, numerical results are provided to demonstrate the tradeoff between energy-efficiency and spectral efficiency.

  2. Mechanisms of cellular transformation by carcinogenic agents

    SciTech Connect (OSTI)

    Grunberger, D.; Goff, S.P.

    1987-01-01

    This book contains 14 chapters. Some of the chapter titles are: DNA Modification by Chemical Carcinogens; Role of DNA Lesions and Repair in the Transformation of Human Cells; The Induction and Regulation of Radiogenic Transformation In Vitro: Cellular and Molecular Mechanisms; Cellular Transformation by Adenoviruses; and The fos Gene.

  3. Location, location, location: utilizing pipelines and services to more effectively georeference the world's biodiversity data

    E-Print Network [OSTI]

    2009-01-01

    location, location: utilizing pipelines and services to morebut also to create pipelines integrated with humanbecome available [8]. These pipelines can be developed to

  4. Efficiency of cellular information processing

    E-Print Network [OSTI]

    Andre C. Barato; David Hartich; Udo Seifert

    2014-11-06

    We show that a rate of conditional Shannon entropy reduction, characterizing the learning of an internal process about an external process, is bounded by the thermodynamic entropy production. This approach allows for the definition of an informational efficiency that can be used to study cellular information processing. We analyze three models of increasing complexity inspired by the E. coli sensory network, where the external process is an external ligand concentration jumping between two values. We start with a simple model for which ATP must be consumed so that a protein inside the cell can learn about the external concentration. With a second model for a single receptor we show that the rate at which the receptor learns about the external environment can be nonzero even without any dissipation inside the cell since chemical work done by the external process compensates for this learning rate. The third model is more complete, also containing adaptation. For this model we show inter alia that a bacterium in an environment that changes at a very slow time-scale is quite inefficient, dissipating much more than it learns. Using the concept of a coarse-grained learning rate, we show for the model with adaptation that while the activity learns about the external signal the option of changing the methylation level increases the concentration range for which the learning rate is substantial.

  5. Impact of Small Cells Location on Performance and QoS of Heterogeneous Cellular Networks

    E-Print Network [OSTI]

    Coupechoux, Marceau

    stations. This analysis is particularly focused on the influence of the position and the transmitting power of the transmitting power of small base stations. An important issue is linked to the interference induced by adding and macro cells. The impact of decreasing the transmitting power of the macro base stations is addressed

  6. Room C180 Administration Building, 105 Administration Place, Saskatoon SK S7N 5A2 Telephone (306) 966-5760; Fax (306) 966-5756; E-mail: gradstudies.awards@usask.ca

    E-Print Network [OSTI]

    Saskatchewan, University of

    Room C180 Administration Building, 105 Administration Place, Saskatoon SK S7N 5A2 Telephone (306 Administration Building, 105 Administration Place, Saskatoon SK S7N 5A2 Telephone (306) 966-5760; Fax (306) 966

  7. Statistical Mechanics of Surjective Cellular Automata

    E-Print Network [OSTI]

    Jarkko Kari; Siamak Taati

    2015-05-14

    Reversible cellular automata are seen as microscopic physical models, and their states of macroscopic equilibrium are described using invariant probability measures. We establish a connection between the invariance of Gibbs measures and the conservation of additive quantities in surjective cellular automata. Namely, we show that the simplex of shift-invariant Gibbs measures associated to a Hamiltonian is invariant under a surjective cellular automaton if and only if the cellular automaton conserves the Hamiltonian. A special case is the (well-known) invariance of the uniform Bernoulli measure under surjective cellular automata, which corresponds to the conservation of the trivial Hamiltonian. As an application, we obtain results indicating the lack of (non-trivial) Gibbs or Markov invariant measures for "sufficiently chaotic" cellular automata. We discuss the relevance of the randomization property of algebraic cellular automata to the problem of approach to macroscopic equilibrium, and pose several open questions. As an aside, a shift-invariant pre-image of a Gibbs measure under a pre-injective factor map between shifts of finite type turns out to be always a Gibbs measure. We provide a sufficient condition under which the image of a Gibbs measure under a pre-injective factor map is not a Gibbs measure. We point out a potential application of pre-injective factor maps as a tool in the study of phase transitions in statistical mechanical models.

  8. Cellular structure in system of interacting particles

    E-Print Network [OSTI]

    Bohdan Lev

    2008-02-21

    The general description of formation the cellular structure in the system of interacting particles is proposed. Interactions between particles are presumably well-understood and the phase transition in which can be studied in the scale of particle resolution. We presented analytical results of possible cellular structures for suspension of colloidal particles, in system particles immersed in liquid crystal and gravitational system. We have shown that cellular structure formation can occur in system of interacting particles for realistic values of temperature and particles concentration.

  9. The structure of cellular networksThe structure of cellular networks To be able to construct and analyze a cellular network, we need

    E-Print Network [OSTI]

    Albert, Réka

    The structure of cellular networksThe structure of cellular networks To be able to construct and analyze a cellular network, we need to clearly define what we identify as a node and what we represent of cellular component (protein, chemical) or the same type of interaction (mass transfer, regulation). We can

  10. Cellular interactions during gastrulation in the amphipod crustacean, Parhyale hawaiensis

    E-Print Network [OSTI]

    Chaw, Ro Crystal

    2011-01-01

    role in organizing cellular architecture and function. CellMullins, R.D. , 2002. Cellular control of actin nucleation.181–203. Hardin, J. , 1996. The Cellular Basis of Sea Urchin

  11. Linear Cellular Automata and Fischer Automata Klaus Sutner

    E-Print Network [OSTI]

    Sutner, Klaus

    Linear Cellular Automata and Fischer Automata Klaus Sutner Carnegie Mellon University Pittsburgh finite state machines associated with linear cellular automata. In particular, we construct a class of binary linear cellular automata whose corresponding mini- mal automata exhibit full exponential blow

  12. Cellular defenses and viral counterattacks during herpes simplex virus infection

    E-Print Network [OSTI]

    Chaurushiya, Mira Suresh

    2011-01-01

    ICP0 insufficient to affect cellular gene expression or cellor abusing: viruses and the cellular DNA damage response.interaction with a 135-kDa cellular protein. Virology 209,

  13. Techniques for green radio cellular communications 

    E-Print Network [OSTI]

    Videv, Stefan

    2013-07-01

    This thesis proposes four novel techniques to solve the problem of growing energy consumption requirements in cellular communication networks. The first and second part of this work propose a novel energy efficient ...

  14. Design of Pressure Actuated Cellular Structures

    E-Print Network [OSTI]

    Markus Pagitz

    2015-08-05

    A novel concept for pressure actuated cellular structures was published in Pagitz et al 2012 Bioinspir. Biomim. 7. The corresponding mathematical foundation for the simulation and optimization of compliant cellular structures with eccentric cell corner hinges was published in Pagitz 2015 arXiv:1403.2197. The aim of this article is threefold: First, analytical expressions for optimal materials of compliant cellular structures with identical properties are derived as a function of cell sizes. It is shown that cellular structures can be made from either a large, small number of highly, lowly pressurized cells that consist of a stiff, soft material. Second, extensions to the previously published numerical model are presented and their application ranges are determined. Third, end cap designs for prismatic cells are developed that can withstand substantial differential pressures while being flexible enough to allow large cross sectional shape changes. Furthermore, a manufacturing approach that is based on cytoskeletons is presented.

  15. The Cricket indoor location system

    E-Print Network [OSTI]

    Priyantha, Nissanka Bodhi, 1968-

    2005-01-01

    Indoor environments present opportunities for a rich set of location-aware applications such as navigation tools for humans and robots, interactive virtual games, resource discovery, asset tracking, location-aware sensor ...

  16. Search Text Based on Locations 

    E-Print Network [OSTI]

    Zhang, Weiwei

    2014-11-21

    locations, which contributes to the Geographical Information Retrieval (GIR) systems. In addition to the traditional applications of GIR systems, which are used for finding locations in documents, GIR can be applied to other fields as well. Firstly, it can...

  17. Telephone Flat Geothermal Development Project Environmental Impact Statement Environmental Impact Report. Final: Comments and Responses to Comments

    SciTech Connect (OSTI)

    1999-02-01

    This document is the Comments and Responses to Comments volume of the Final Environmental Impact Statement and Environmental Impact Report prepared for the proposed Telephone Flat Geothermal Development Project (Final EIS/EIR). This volume of the Final EIS/EIR provides copies of the written comments received on the Draft EIS/EIR and the leady agency responses to those comments in conformance with the requirements of the National Environmental Policy Act (NEPA) and the California Environmental Quality Act (CEQA).

  18. Location, location, location: The variable value of renewable energy and demand-side efficiency resources

    E-Print Network [OSTI]

    Fowlie, Meredith

    and renewable energy resources. We eval- uate renewable energy (RE) and energy efficiency (EE) technologiesLocation, location, location: The variable value of renewable energy and demand-side efficiency mitigation efforts in the electricity sector emphasize accelerated deployment of energy efficiency measures

  19. Dartmouth College HANOVER NEW HAMPSHIRE 03755-1420 Safety and Security 5 Rope Ferry Road #6156 Telephone (603) 646-4000 Fax (603) 646-1603

    E-Print Network [OSTI]

    Dartmouth College HANOVER · NEW HAMPSHIRE · 03755-1420 Safety and Security · 5 Rope Ferry Road #6156 · Telephone (603) 646-4000 · Fax (603) 646-1603 Dear New Students; I want to welcome each of you

  20. Cellular automata with vanishing particles Petr K urka

    E-Print Network [OSTI]

    Kurka, Petr

    Cellular automata with vanishing particles Petr K#23;urka Faculty of Mathematics and Physics a cellular automaton, we search for particle weight functions, for which the total weights of con#12 that this happens in the elementary cellular automaton rule number 18 and in the Gacs-Kurdyumov-Levin cellular

  1. Quantum Cellular Automaton Theory of Light Alessandro Bisio,

    E-Print Network [OSTI]

    D'Ariano, Giacomo Mauro

    Quantum Cellular Automaton Theory of Light Alessandro Bisio, Giacomo Mauro D'Ariano, and Paolo on quantum cellular automata (QCA). This approach allows us to have a thorough quantum theory of free. INTRODUCTION The Quantum Cellular Automaton (QCA) is the quan- tum version of the popular cellular automaton

  2. Hiding Location Information from Location-Based Services

    E-Print Network [OSTI]

    Hengartner, Urs

    that the architecture is powerful enough to support existing location- based services. Our architecture exploits Trusted-specific information is being accessed. I. INTRODUCTION The ubiquity of cellphones has lead to the introduction of a cellphone user (e.g., directions to a target location or a list of interesting, nearby places). Another

  3. Commencement Ceremony Department Time Location Department and Major Time Location

    E-Print Network [OSTI]

    Kaji, Hajime

    Engineering 15:30 Bldg. 63 Classroom 01 (2nd Fl.) Industrial and Management Systems Engineering 15:30 Bldg. 63 and Management 15:30 Bldg. 63 Classroom 01 (2nd Fl.) Department Time Location Department and Major Time Location:30 Bldg. 57 202 Modern Mechanical Engineering 10:30 Bldg. 57 202 Industrial and Management Systems

  4. Location Management for Mobile Devices

    E-Print Network [OSTI]

    Wilde, Erik

    2008-01-01

    general, and wireless and mobile devices in particular. Thelocation-enabled mobile devices and location-based services.information from mobile devices and making it available to

  5. Toxicology and cellular effect of manufactured nanomaterials

    DOE Patents [OSTI]

    Chen, Fanqing

    2014-07-22

    The increasing use of nanotechnology in consumer products and medical applications underlies the importance of understanding its potential toxic effects to people and the environment. Herein are described methods and assays to predict and evaluate the cellular effects of nanomaterial exposure. Exposing cells to nanomaterials at cytotoxic doses induces cell cycle arrest and increases apoptosis/necrosis, activates genes involved in cellular transport, metabolism, cell cycle regulation, and stress response. Certain nanomaterials induce genes indicative of a strong immune and inflammatory response within skin fibroblasts. Furthermore, the described multiwall carbon nanoonions (MWCNOs) can be used as a therapeutic in the treatment of cancer due to its cytotoxicity.

  6. Algorithmic crystal chemistry: A cellular automata approach

    SciTech Connect (OSTI)

    Krivovichev, S. V.

    2012-01-15

    Atomic-molecular mechanisms of crystal growth can be modeled based on crystallochemical information using cellular automata (a particular case of finite deterministic automata). In particular, the formation of heteropolyhedral layered complexes in uranyl selenates can be modeled applying a one-dimensional three-colored cellular automaton. The use of the theory of calculations (in particular, the theory of automata) in crystallography allows one to interpret crystal growth as a computational process (the realization of an algorithm or program with a finite number of steps).

  7. Cellular Automata with Symmetric Local Rules

    E-Print Network [OSTI]

    Vladimir V. Kornyak

    2006-09-18

    The cellular automata with local permutation invariance are considered. We show that in the two-state case the set of such automata coincides with the generalized Game of Life family. We count the number of equivalence classes of the rules under consideration with respect to permutations of states. This reduced number of rules can be efficiently generated in many practical cases by our C program. Since a cellular automaton is a combination of a local rule and a lattice, we consider also maximally symmetric two-dimensional lattices. In addition, we present the results of compatibility analysis of several rules from the Life family.

  8. Mobile Alternative Fueling Station Locator

    SciTech Connect (OSTI)

    Not Available

    2009-04-01

    The Department of Energy's Alternative Fueling Station Locator is available on-the-go via cell phones, BlackBerrys, or other personal handheld devices. The mobile locator allows users to find the five closest biodiesel, electricity, E85, hydrogen, natural gas, and propane fueling sites using Google technology.

  9. Guide to the Library Locations

    E-Print Network [OSTI]

    Massachusetts at Amherst, University of

    Guide to the Libraries #12;Library Locations W.E.B. DU BOIS LIBRARY www.library.umass.edu 154 Hicks Way (413) 545-0150, (413) 545-2622 The Du Bois Library is the primary location for resources in education, geography, the humanities and fine arts, nursing, management, medicine, public health, and social

  10. Cellular CSK resembles natural and synthetic materials

    E-Print Network [OSTI]

    Sniadecki, Nathan J.

    Theory Pinned-pinned, three-point bending Es is modulus of elasticity for beam (F-actin GPa) d 3 48 s F l E ISession 15 #12;2 Cellular CSK resembles natural and synthetic materials Felt Paper Cotton NASA r r #12;6 (a/k/a Second Moment of Area) Geometric resistance of a beam to bending 2 2

  11. Proportionally Fair Selective Cooperation for Cellular Networks

    E-Print Network [OSTI]

    Leung, Kin K.

    Proportionally Fair Selective Cooperation for Cellular Networks: Algorithm, Simulation and Analysis, a node and a cooperative relay are selected in a proportionally fair (PF) manner to transmit to the base cooperative transmissions, and is called proportionally fair selective cooperation (PFSC). This tech- nique

  12. Periodic cellular automata and Bethe ansatz

    E-Print Network [OSTI]

    Atsuo Kuniba; Akira Takenouchi

    2006-01-07

    We review and generalize the recent progress in a soliton cellular automaton known as the periodic box-ball system. It has the extended affine Weyl group symmetry and admits the commuting transfer matrix method and the Bethe ansatz at q=0. Explicit formulas are proposed for the dynamical period and the number of states characterized by conserved quantities.

  13. Quality of service analysis for audio over cellular voice networks and cellular wireless wide area networks

    E-Print Network [OSTI]

    Malik, Omair S. (Omair Safwan)

    2007-01-01

    Cellular Wireless Wide Area Networks (WWANs) are most prevalent and offer high-bandwidth data transfer. We believe WWANs can be availed for voice communications employing Voice Over IP technologies. Such a communication ...

  14. GSM Whitespaces: An Opportunity for Rural Cellular Service

    E-Print Network [OSTI]

    California at Berkeley, University of

    , community cellular, that has the potential to bring coverage to extremely rural populations. Although the total capital costs for these networks (rural communities, the highGSM Whitespaces: An Opportunity for Rural Cellular Service Shaddi Hasan, Kurtis Heimerl, Kate

  15. Integrated characterization of cellular physiology underlying hepatic metabolism

    E-Print Network [OSTI]

    Wong, Matthew Sing

    2006-01-01

    The macroscopic metabolic phenotype of a cellular system, such as insulin resistance, is the result of the integration of many hundreds or thousands of preceding cellular events, which culminates in the cell's final response ...

  16. Molecular & Cellular Biology Program Departmental Retreats Autumn 2014

    E-Print Network [OSTI]

    Doty, Sharon Lafferty

    Molecular & Cellular Biology Program Departmental Retreats ­ Autumn 2014 Z:\\FRONT DESK DOCUMENTS Hutchinson Cancer Research Center (FHCRC) 1100 Fairview Ave. N. Seattle, WA 98109-1024 Molecular & Cellular

  17. Cellular CSK resembles natural and synthetic materials

    E-Print Network [OSTI]

    Sniadecki, Nathan J.

    -pinned, three-point bending 7 Es is modulus of elasticity for beam (F-actin GPa) 3 48 s F l E I = #12;StressSession 15 #12;Cellular CSK resembles natural and synthetic materials Felt Paper Cotton 2 Cotton = #12;(a/k/a Second Moment of Area) Geometric resistance of a beam to bending 2 x A I y dA= y 6 2 4 4 4

  18. Statistical equilibrium in deterministic cellular automata

    E-Print Network [OSTI]

    Siamak Taati

    2015-05-24

    Some deterministic cellular automata have been observed to follow the pattern of the second law of thermodynamics: starting from a partially disordered state, the system evolves towards a state of equilibrium characterized by maximal disorder. This chapter is an exposition of this phenomenon and of a statistical scheme for its explanation. The formulation is in the same vein as Boltzmann's ideas, but the simple combinatorial setup offers clarification and hope for generic mathematically rigorous results. Probabilities represent frequencies and subjective interpretations are avoided.

  19. Optimization Online - Radio Planning of Energy-Aware Cellular ...

    E-Print Network [OSTI]

    Nov 3, 2010 ... Radio Planning of Energy-Aware Cellular Networks ... Keywords: green networking, wireless, network design, coverage, network management, ...

  20. Cellular Automata with an Infinite Number of Subshift Attractors

    E-Print Network [OSTI]

    Kurka, Petr

    Cellular Automata with an Infinite Number of Subshift Attractors Petr K °urka Center that the complexity of a cellular automaton is reflected in the complexity of the lattice of its subshift attractors (i.e., of those attractors which are subshifts). We construct cellular automata with an infinite

  1. Cellular Characterization of Leukotoxin Diol-Induced Mitochondrial Dysfunction

    E-Print Network [OSTI]

    Hammock, Bruce D.

    Cellular Characterization of Leukotoxin Diol-Induced Mitochondrial Dysfunction Marlene F. Sisemore- vation step in leukotoxin-induced cellular toxicity. In both human and insect cells, we observed that leuko- toxin diol causes acute cellular toxicity and that cyclo- sporin A, an inhibitor

  2. Cyclic Cellular Automata in 3D Clifford A. Reiter

    E-Print Network [OSTI]

    Reiter, Clifford A.

    Cyclic Cellular Automata in 3D Clifford A. Reiter Department of Mathematics, Lafayette College, Easton, PA 18042 U.S.A reiterc@lafayette.edu Abstract Cyclic cellular automata in two dimensions have this work to three dimensional cyclic cellular automata and observe self organization dependent upon

  3. Cellular Metals Manufacturing** By Haydn N. G. Wadley*

    E-Print Network [OSTI]

    Wadley, Haydn

    Cellular Metals Manufacturing** By Haydn N. G. Wadley* 1. Manufacturing Methods Overview As the engineering applications of cellular metals grows, many methods for their manufacture are being developed.[1 manufacturing methods. Those with high relative density, r/ rs >0.5 (where r is the cellular metals density

  4. Enhancing Cellular Multicast Performance Using Ad Hoc Networks

    E-Print Network [OSTI]

    Kasera, Sneha Kumar

    Enhancing Cellular Multicast Performance Using Ad Hoc Networks Jun Cheol Park and Sneha Kumar heterogeneity problem in cellular multicast with the help of an additional IEEE 802.11 ad hoc network. The basic idea is to allow the cellular receivers experiencing poor channel conditions to use the ad hoc network

  5. MIST: Cellular Data Network Measurement for Mobile Applications

    E-Print Network [OSTI]

    Belding-Royer, Elizabeth M.

    1 MIST: Cellular Data Network Measurement for Mobile Applications Mike P. Wittie, Brett Stone-- The rapid growth in the popularity of cellular networks has led to aggressive deployment and a rapid to the deployment of many of these services is poor or unknown network performance, particularly in the cellular

  6. Affine cellular algebras Steffen Koenig and Changchang Xi1

    E-Print Network [OSTI]

    Xi, Changchang

    Affine cellular algebras Steffen Koenig and Changchang Xi1 Abstract Graham and Lehrer have defined cellular algebras and developed a theory that allows in particular to classify simple representations of finite dimensional cellular algebras. Many classes of finite dimensional algebras, including various

  7. CELLULAR AUTOMATA MODELS: A SANDPILE MODEL APPLIED IN FUSION

    E-Print Network [OSTI]

    Anastasiadis, Anastasios

    CELLULAR AUTOMATA MODELS: A SANDPILE MODEL APPLIED IN FUSION Anastasios Anastasiadis Institute present the basic properties of a simple cellular automaton (CA) model proposed for the study insights regarding the dynamics of magnetically confined plasmas. 1 CELLULAR AUTOMATA AND SELF ORGANIZED

  8. MIST: Cellular Data Network Measurement for Mobile Applications

    E-Print Network [OSTI]

    Almeroth, Kevin C.

    MIST: Cellular Data Network Measurement for Mobile Applications Mike P. Wittie, Brett Stone Paper) Abstract-- The rapid growth in the popularity of cellular networks has led to aggressive deployment and a rapid expansion of mobile services. Services based on the integration of cellular networks

  9. Cellular Allometry: The Spindle in Development and Inheritance

    E-Print Network [OSTI]

    Needleman, Daniel

    Dispatches Cellular Allometry: The Spindle in Development and Inheritance Recent studies have embryogenesis, giving insight into how a core cellular process is modulated over the course of development how core cellular processes are modified to function in different cells. The basic mechanisms

  10. Cellular Automata Model of Cystogenesis and Tubulogenesis Elhanan Borenstein

    E-Print Network [OSTI]

    Borenstein, Elhanan

    Cellular Automata Model of Cystogenesis and Tubulogenesis Elhanan Borenstein School of Computer of Molecular & Cellular Physiology Stanford University, Stanford, CA 94305, USA egcline@stanford.edu Abstract not initially have a lumen. Our model is an extension of the Cellular Potts Model (CPM), a commonly used

  11. Cellular pattern formation in circular domains Antonio Palacios,a)

    E-Print Network [OSTI]

    Cellular pattern formation in circular domains Antonio Palacios,a) Gemunu H. Gunaratne 1997; accepted for publication 24 June 1997 An analysis of stationary and nonstationary cellular. Motivated by the observa- tion of novel stationary and nonstationary cellular states on a flame front, we

  12. Reliable Cellular Automata with SelfOrganization Peter Gacs 1

    E-Print Network [OSTI]

    Gacs, Peter

    Reliable Cellular Automata with Self­Organization Peter Gâ??acs 1 Computer Science Department Boston University Boston, MA 02215 gacs@bu.edu Abstract In a noisy cellular automaton, even if it is infinite solution in 2 dimensions has been applied to a simple 3­dimensional fault­tolerant cellular automaton

  13. RELIABLE CELLULAR AUTOMATA WITH SELF-ORGANIZATION PETER G ACS

    E-Print Network [OSTI]

    Gacs, Peter

    RELIABLE CELLULAR AUTOMATA WITH SELF-ORGANIZATION PETER G ´ACS ABSTRACT. In a probabilistic cellular automaton in which all local transitions have positive probability, the problem of keeping a bit-tolerant cellular automaton. This technique does not help much to solve the following problems: remembering a bit

  14. Cellular Automata and Intermediate Degrees Computer Science Department

    E-Print Network [OSTI]

    Sutner, Klaus

    Cellular Automata and Intermediate Degrees K. Sutner Computer Science Department Carnegie Mellon University Pittsburgh, PA 15213 Abstract We study a classification of cellular automata based on the Turing degree of the orbits of the automaton. The difficulty of determining the membership of a cellular

  15. THE CELLULAR STRUCTURE OF THE CLASSIFYING SPACES OF FINITE GROUPS

    E-Print Network [OSTI]

    Foote, Richard M.

    THE CELLULAR STRUCTURE OF THE CLASSIFYING SPACES OF FINITE GROUPS RAM´ON J. FLORES AND RICHARD M. FOOTE Abstract. In this paper we obtain a description of the BZ/p-cellularization (in the sense of Dror is called A-cellular if it can be constructed as an (iterated) pointed homotopy colimit of copies of A

  16. Cellular oscillations and the regulation of growth: the

    E-Print Network [OSTI]

    Kunkel, Joseph G.

    Cellular oscillations and the regulation of growth: the pollen tube paradigm Jose A. Feijo ,1. There is evidence that these cellular oscillators involve an integrated input of plasma membrane ion fluxes for the study of growth and morphogenesis at the cellular level. Being the carriers of male gametes in all

  17. Cellular membrane trafficking of mesoporous silica nanoparticles

    SciTech Connect (OSTI)

    Fang, I-Ju

    2012-06-21

    This dissertation mainly focuses on the investigation of the cellular membrane trafficking of mesoporous silica nanoparticles. We are interested in the study of endocytosis and exocytosis behaviors of mesoporous silica nanoparticles with desired surface functionality. The relationship between mesoporous silica nanoparticles and membrane trafficking of cells, either cancerous cells or normal cells was examined. Since mesoporous silica nanoparticles were applied in many drug delivery cases, the endocytotic efficiency of mesoporous silica nanoparticles needs to be investigated in more details in order to design the cellular drug delivery system in the controlled way. It is well known that cells can engulf some molecules outside of the cells through a receptor-ligand associated endocytosis. We are interested to determine if those biomolecules binding to cell surface receptors can be utilized on mesoporous silica nanoparticle materials to improve the uptake efficiency or govern the mechanism of endocytosis of mesoporous silica nanoparticles. Arginine-glycine-aspartate (RGD) is a small peptide recognized by cell integrin receptors and it was reported that avidin internalization was highly promoted by tumor lectin. Both RGD and avidin were linked to the surface of mesoporous silica nanoparticle materials to investigate the effect of receptor-associated biomolecule on cellular endocytosis efficiency. The effect of ligand types, ligand conformation and ligand density were discussed in Chapter 2 and 3. Furthermore, the exocytosis of mesoporous silica nanoparticles is very attractive for biological applications. The cellular protein sequestration study of mesoporous silica nanoparticles was examined for further information of the intracellular pathway of endocytosed mesoporous silica nanoparticle materials. The surface functionality of mesoporous silica nanoparticle materials demonstrated selectivity among the materials and cancer and normal cell lines. We aimed to determine the specific organelle that mesoporous silica nanoparticles could approach via the identification of harvested proteins from exocytosis process. Based on the study of endo- and exocytosis behavior of mesoporous silica nanoparticle materials, we can design smarter drug delivery vehicles for cancer therapy that can be effectively controlled. The destination, uptake efficiency and the cellular distribution of mesoporous silica nanoparticle materials can be programmable. As a result, release mechanism and release rate of drug delivery systems can be a well-controlled process. The deep investigation of an endo- and exocytosis study of mesoporous silica nanoparticle materials promotes the development of drug delivery applications.

  18. The cellular mechanisms of learning in Aplysia: Of blind men and elephants

    E-Print Network [OSTI]

    Glanzman, David L

    2006-01-01

    postsynaptic mechanisms in a cellular analog of classical4019. Byrne, J. H. 1987. Cellular analysis of associativecorrelation of behavioral and cellular processes. Science

  19. Cellular and molecular mechanisms underlying tissue elongation of the developing egg in Drosophila melanogaster

    E-Print Network [OSTI]

    Haigo, Saori Lillian

    2011-01-01

    affecting cell fates and cellular rearrangements duringOriented cell divisions and cellular morphogenesis in theand Keller, R. (1997). Cellular mechanism underlying neural

  20. Cellular Senescence in Livers from Children with End Stage Liver Disease

    E-Print Network [OSTI]

    2010-01-01

    J (2000) Cancer, aging and cellular senescence. In Vivo 14:and mitochondria during cellular senescence: is there aCN (2007) Methods of cellular senescence induction using

  1. Frontiers in Cellular Neuroscience www.frontiersin.org March 2010 | Volume 4 | Article 3 | 1 CELLULAR NEUROSCIENCE

    E-Print Network [OSTI]

    Reid, R. Clay

    Frontiers in Cellular Neuroscience www.frontiersin.org March 2010 | Volume 4 | Article 3 | 1 CELLULAR NEUROSCIENCE METHODS ARTICLE published: 12 March 2010 doi: 10.3389/fncel.2010.00003 information., 2007; Chen et al., 2008). These studies have all inferred cellular identity from extracellular spike

  2. WORKPLACE HAZARD ASSESSMENT Location: Task

    E-Print Network [OSTI]

    Rubloff, Gary W.

    WORKPLACE HAZARD ASSESSMENT Location: Task: Performed by: Date: This form may be used as an aid in performing hazard assessment. Review listed hazard classifications, identify all hazards, possible hazards and their sources. Hazard classification listing is not intended to be complete but is provided as a guide

  3. Quantumness of discrete Hamiltonian cellular automata

    E-Print Network [OSTI]

    Hans-Thomas Elze

    2014-07-08

    We summarize a recent study of discrete (integer-valued) Hamiltonian cellular automata (CA) showing that their dynamics can only be consistently defined, if it is linear in the same sense as unitary evolution described by the Schr\\"odinger equation. This allows to construct an invertible map between such CA and continuous quantum mechanical models, which incorporate a fundamental scale. Presently, we emphasize general aspects of these findings, the construction of admissible CA observables, and the existence of solutions of the modified dispersion relation for stationary states.

  4. Telephone Flat Geothermal Development Project Environmental Impact Statement Environmental Impact Report. Final

    SciTech Connect (OSTI)

    1999-02-01

    This Final Environmental Impact Statement and Environmental Impact Report (Final EIS/EIR) has been prepared to meet the requirements of the National Environmental Policy Act (NEPA) and the California Environmental Quality Act (CEQA). The Proposed Action includes the construction, operation, and decommissioning of a 48 megawatt (gross) geothermal power plant with ancillary facilities (10-12 production well pads and 3-5 injection well pads, production and injection pipelines), access roads, and a 230-kilovolt (kV) transmission line in the Modoc National Forest in Siskiyou County, California. Alternative locations for the power plant site within a reasonable distance of the middle of the wellfield were determined to be technically feasible. Three power plant site alternatives are evaluated in the Final EIS/EIR.

  5. New insights on the Dynamic Cellular Metabolism

    E-Print Network [OSTI]

    Ildefonso M. De la Fuente

    2015-01-09

    A large number of studies have shown the existence of metabolic covalent modifications in different molecular structures, able to store biochemical information that is not encoded by the DNA. Some of these covalent mark patterns can be transmitted across generations (epigenetic changes). Recently, the emergence of Hopfield-like attractor dynamics has been observed in the self-organized enzymatic networks, which have the capacity to store functional catalytic patterns that can be correctly recovered by the specific input stimuli. The Hopfield-like metabolic dynamics are stable and can be maintained as a long-term biochemical memory. In addition, specific molecular information can be transferred from the functional dynamics of the metabolic networks to the enzymatic activity involved in the covalent post-translational modulation so that determined functional memory can be embedded in multiple stable molecular marks. Both the metabolic dynamics governed by Hopfield-type attractors (functional processes) and the enzymatic covalent modifications of determined molecules (structural dynamic processes) seem to represent the two stages of the dynamical memory of cellular metabolism (metabolic memory). Epigenetic processes appear to be the structural manifestation of this cellular metabolic memory. Here, a new framework for molecular information storage in the cell is presented, which is characterized by two functionally and molecularly interrelated systems: a dynamic, flexible and adaptive system (metabolic memory) and an essentially conservative system (genetic memory). The molecular information of both systems seems to coordinate the physiological development of the whole cell.

  6. A Cellular Automaton Model of Pulsar Glitches

    E-Print Network [OSTI]

    L. Warszawski; A. Melatos

    2008-06-29

    A cellular automaton model of pulsar glitches is described, based on the superfluid vortex unpinning paradigm. Recent analyses of pulsar glitch data suggest that glitches result from scale-invariant avalanches \\citep{Melatos07a}, which are consistent with a self-organized critical system (SOCS). A cellular automaton provides a computationally efficient means of modelling the collective behaviour of up to $10^{16}$ vortices in the pulsar interior, whilst ensuring that the dominant aspects of the microphysics are not lost. The automaton generates avalanche distributions that are qualitatively consistent with a SOCS and with glitch data. The probability density functions of glitch sizes and durations are power laws, and the probability density function of waiting times between successive glitches is Poissonian, consistent with statistically independent events. The output of the model depends on the physical and computational paramters used. The fitted power law exponents for the glitch sizes ($a$) and durations ($b$) decreases as the strength of the vortex pinning increases. Similarly the exponents increase as the fraction of vortices that are pinned decreases. For the physical and computational parameters considered, one finds $-4.3\\leq a \\leq -2.0$ and $-5.5\\leq b\\leq -2.2$, and mean glitching rates in the range $0.0023\\leq\\lambda\\leq0.13\\$ in units of inverse time.

  7. Dartmouth College HANOVER NEW HAMPSHIRE 03755-1420 Safety and Security 5 Rope Ferry Road #6156 Telephone (603) 646-4000 Fax (603) 646-1603

    E-Print Network [OSTI]

    Dartmouth College HANOVER · NEW HAMPSHIRE · 03755-1420 Safety and Security · 5 Rope Ferry Road students; and that is our greatest concern. New Hampshire laws pertaining to underage drinking, hazing #6156 · Telephone (603) 646-4000 · Fax (603) 646-1603 Dear New Student Parents and Families

  8. University of Hawai`i, Board of Regents, Bachman 209, 2444 Dole Street, Honolulu, HI 96822 Telephone No. (808) 956-8213; Fax No. (808) 956-5156

    E-Print Network [OSTI]

    University of Hawai`i, Board of Regents, Bachman 209, 2444 Dole Street, Honolulu, HI 96822 4303 Diamond Head Road Honolulu, HI 96816 AGENDA I. Call Meeting to Order II. Approval of Meeting, Bachman 209, 2444 Dole Street, Honolulu, HI 96822 Telephone No. (808) 956-8213; Fax No. (808) 956-5156 VI

  9. Joint microseismic event location with uncertain velocity

    E-Print Network [OSTI]

    Poliannikov, Oleg V.

    2013-01-01

    We study the problem of the joint location of seismic events using an array of receivers. We show that locating multiple seismic events simultaneously is advantageous compared to the more traditional approaches of locating ...

  10. Location and Hours | ornl.gov

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Location and Hours Location The ORNL Research Library is located off the central corridor of Bldg. 4500N on the main ORNL campus. Hours The library is open 24 hours, seven days a...

  11. Optimized Fault Location Final Project Report

    E-Print Network [OSTI]

    Optimized Fault Location Final Project Report Power Systems Engineering Research Center A National Engineering Research Center Optimized Fault Location Concurrent Technologies Corporation Final Project Report

  12. Energy Department Launches Alternative Fueling Station Locator...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Launches Alternative Fueling Station Locator App Energy Department Launches Alternative Fueling Station Locator App November 7, 2013 - 11:16am Addthis As part of the Obama...

  13. Cellular membrane collapse by atmospheric-pressure plasma jet

    SciTech Connect (OSTI)

    Kim, Kangil; Sik Yang, Sang E-mail: ssyang@ajou.ac.kr; Jun Ahn, Hak; Lee, Jong-Soo E-mail: ssyang@ajou.ac.kr; Lee, Jae-Hyeok; Kim, Jae-Ho

    2014-01-06

    Cellular membrane dysfunction caused by air plasma in cancer cells has been studied to exploit atmospheric-pressure plasma jets for cancer therapy. Here, we report that plasma jet treatment of cervical cancer HeLa cells increased electrical conductivity across the cellular lipid membrane and caused simultaneous lipid oxidation and cellular membrane collapse. We made this finding by employing a self-manufactured microelectrode chip. Furthermore, increased roughness of the cellular lipid membrane and sequential collapse of the membrane were observed by atomic force microscopy following plasma jet treatment. These results suggest that the cellular membrane catastrophe occurs via coincident altered electrical conductivity, lipid oxidation, and membrane roughening caused by an atmospheric-pressure plasma jet, possibly resulting in cellular vulnerability to reactive species generated from the plasma as well as cytotoxicity to cancer cells.

  14. Ombuds Office Location & Hours

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room NewsInformationJesseworkSURVEY UNIVERSEHowScientificOmbuds Office Location & Hours Ombuds

  15. Heterogeneous Force Chains in Cellularized Biopolymer Network

    E-Print Network [OSTI]

    Liang, Long; Sun, Bo; Jiao, Yang

    2015-01-01

    Biopolymer Networks play an important role in coordinating and regulating collective cellular dynamics via a number of signaling pathways. Here, we investigate the mechanical response of a model biopolymer network due to the active contraction of embedded cells. Specifically, a graph (bond-node) model derived from confocal microscopy data is used to represent the network microstructure, and cell contraction is modeled by applying correlated displacements at specific nodes, representing the focal adhesion sites. A force-based stochastic relaxation method is employed to obtain force-balanced network under cell contraction. We find that the majority of the forces are carried by a small number of heterogeneous force chains emitted from the contracting cells. The force chains consist of fiber segments that either possess a high degree of alignment before cell contraction or are aligned due to the reorientation induced by cell contraction. Large fluctuations of the forces along different force chains are observed. ...

  16. Available online at www.sciencedirect.com FoxO transcription factors in the maintenance of cellular

    E-Print Network [OSTI]

    Brunet, Anne

    that coordinate a wide range of cellular outputs. FoxO- dependent cellular responses include gluconeogenesis

  17. Fluorescent dyes for probing cellular functions associated with...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    fluorescence dyes suitable for visualization of specific cellular functions associated with electron beam damage and carry out electron microscopy imaging of labelled cells....

  18. Cellular/Mollecular Intracellular Patch Electrochemistry: Regulation of Cytosolic

    E-Print Network [OSTI]

    Sulzer, David

    Cellular/Mollecular Intracellular Patch Electrochemistry: Regulation of Cytosolic Catecholamines intracellular patch electrochemistry (IPE), a tech- nique that for the first time provides direct measurements

  19. Radio Planning of Energy-Aware Cellular Networks

    E-Print Network [OSTI]

    Silvia Boiardi

    2010-11-03

    Nov 3, 2010 ... Radio Planning of Energy-Aware Cellular Networks. Silvia Boiardi(Silvia.Boiardi ***at*** gerad.ca) Capone Antonio(antonio.capone ***at*** ...

  20. Evaluating Mappings for Cellular Automata Music Alexis Kirke1

    E-Print Network [OSTI]

    Miranda, Eduardo Reck

    Evaluating Mappings for Cellular Automata Music Alexis Kirke1 , Eduardo Miranda1 1 Interdisciplinary Centre for Computer Music Research (ICCMR), University of Plymouth, Plymouth, UK {Alexis.Kirke

  1. Cellular Decision Making and Biological Noise: From Microbes to Mammals

    E-Print Network [OSTI]

    Balazsi, Gabor

    Cellular decision making is the process whereby cells assume different, functionally important and heritable fates without an associated genetic or environmental difference. Such stochastic cell fate decisions generate ...

  2. Short range radio locator system

    DOE Patents [OSTI]

    McEwan, T.E.

    1996-12-31

    A radio location system comprises a wireless transmitter that outputs two megahertz period bursts of two gigahertz radar carrier signals. A receiver system determines the position of the transmitter by the relative arrival of the radar bursts at several component receivers set up to have a favorable geometry and each one having a known location. One receiver provides a synchronizing gating pulse to itself and all the other receivers. The rate of the synchronizing gating pulse is slightly offset from the rate of the radar bursts themselves, so that each sample collects one finely-detailed piece of information about the time-of-flight of the radar pulse to each receiver each pulse period. Thousands of sequential pulse periods provide corresponding thousand of pieces of information about the time-of-flight of the radar pulse to each receiver, in expanded, not real time. Therefore the signal processing can be done with relatively low-frequency, inexpensive components. A conventional microcomputer is then used to find the position of the transmitter by geometric triangulation based on the relative time-of-flight information. 5 figs.

  3. Short range radio locator system

    DOE Patents [OSTI]

    McEwan, Thomas E. (Livermore, CA)

    1996-01-01

    A radio location system comprises a wireless transmitter that outputs two megahertz period bursts of two gigahertz radar carrier signals. A receiver system determines the position of the transmitter by the relative arrival of the radar bursts at several component receivers set up to have a favorable geometry and each one having a known location. One receiver provides a synchronizing gating pulse to itself and all the other receivers to sample the ether for the radar pulse. The rate of the synchronizing gating pulse is slightly offset from the rate of the radar bursts themselves, so that each sample collects one finely-detailed piece of information about the time-of-flight of the radar pulse to each receiver each pulse period. Thousands of sequential pulse periods provide corresponding thousand of pieces of information about the time-of-flight of the radar pulse to each receiver, in expanded, not real time. Therefore the signal processing can be done with relatively low-frequency, inexpensive components. A conventional microcomputer is then used to find the position of the transmitter by geometric triangulation based on the relative time-of-flight information.

  4. Probabilistic Discovery of Overlapping Cellular Processes and Their Regulation

    E-Print Network [OSTI]

    Batzoglou, Serafim

    Probabilistic Discovery of Overlapping Cellular Processes and Their Regulation Alexis Battle providing a more biologically plausible model for the process of gene regulation. We present an algorithm be gained by modeling both the organization of genes into overlapping cellular processes and the regulatory

  5. Outage and Capacity Analysis of Cellular CDMA With Admission Control

    E-Print Network [OSTI]

    Chockalingam, A.

    Outage and Capacity Analysis of Cellular CDMA With Admission Control S. AnandÝ , A. Chockalingam. Ltd., Bangalore, INDIA Abstract-- We analyze the outage and capacity performance of an interference based admission control strategy in cellular CDMA systems. Most approaches to estimate the outage

  6. Stochastic Power Control for Cellular Radio Systems \\Lambda

    E-Print Network [OSTI]

    Yates, Roy

    Stochastic Power Control for Cellular Radio Systems \\Lambda Sennur Ulukus Roy D. Yates July 11 In cellular wireless communication systems, the aim of power control is to assign each user a transmitter power level such that all users satisfy their quality of service (QoS) requirements. The power control

  7. COMPLETIONS OF CELLULAR ALGEBRAS R.M. Green

    E-Print Network [OSTI]

    Green, Richard M.

    COMPLETIONS OF CELLULAR ALGEBRAS R.M. Green.M. GREEN One of the strengths of the theory of cellular algebras is that it provides a complete list Lancaster LA1 4YF England E-mail: r.m.green

  8. PAS kinase is required for normal cellular energy balance

    E-Print Network [OSTI]

    Rutter, Jared

    PAS kinase is required for normal cellular energy balance Huai-Xiang Hao*, Caleb M. Cardon*, Wojtek in a cell-autonomous manner to maintain cellular energy homeostasis and is a potential therapeutic target). The World Health Organization estimates that the current decade will witness a 46% increase in diabetes

  9. Optical spectroscopy noninvasively monitors response of organelles to cellular stress

    E-Print Network [OSTI]

    Palanker, Daniel

    detection of cellular stress is ex- tremely useful for fundamental research and practical applications the transformations in cellular organelles under thermal stress. At the temperatures triggering expression of heat stress. © 2005 Society of Photo-Optical Instrumentation Engineers. DOI: 10.1117/1.2075207 Keywords

  10. BIOLOGICAL FRAMEWORKS FOR ENGINEERS Session #14 [Cellular Energetics

    E-Print Network [OSTI]

    Sniadecki, Nathan J.

    : Discuss the importance of energy to the body and metabolism Discuss cellular respiration in detail of chemical bonds into free energy for the cell to utilize; nature's storage and handling of energy may provide insight into our engineering of energy solutions Interactive Activity: Discussions on cellular

  11. A STOCHASTIC CELLULAR AUTOMATON MODEL OF EBOLA VIRUS DYNAMICS

    E-Print Network [OSTI]

    Hawkins, Jane M.

    A STOCHASTIC CELLULAR AUTOMATON MODEL OF EBOLA VIRUS DYNAMICS E. BURKHEAD AND J. HAWKINS Abstract. We construct a stochastic cellular automaton (SCA) model for the spread of the Ebola virus (EBOV). We of virus and the typical immune response to it, and the differences which reflect the drastically different

  12. Cellular Algebras and Graph Invariants Based on Quantum Walks

    E-Print Network [OSTI]

    Jamie Smith

    2011-03-01

    We consider two graph invariants inspired by quantum walks- one in continuous time and one in discrete time. We will associate a matrix algebra called a cellular algebra with every graph. We show that, if the cellular algebras of two graphs have a similar structure, then they are not distinguished by either of the proposed invariants.

  13. Cellular structures in the high-latitude thermosphere

    SciTech Connect (OSTI)

    Crowley, G. [Johns Hopkins Univ. Laurel, MD (United States)] [Johns Hopkins Univ. Laurel, MD (United States); Schoendorf, J.; Roble, R.G. [NCAR, Boulder, CO (United States)] [and others] [NCAR, Boulder, CO (United States); and others

    1996-01-01

    An organized density (and pressure) structure was recently discovered in the neutral thermosphere at high-latitudes. The structure consists of two to four high- and low-density regions having diameters of 1000 to 2000 km. The density in each region is enhanced or depleted from the hemispheric average by up to 30%. The structure is thus a significant feature of the near-Earth space environment at high-latitudes. The authors refer to each distinct region of enhanced or depleted density as a density {open_quotes}cell.{close_quotes} The cells extend upward from about 120 km into the upper thermosphere, and once formed they remain approximately fixed with respect to the geomagnetic pole. A parametric study of the density cell morphology for different magnetic activity levels is described for equinox solar minimum using the National Center for Atmospheric Research thermosphere ionosphere general circulation model (NCAR model). The TIGCM simulations were used to predict the large density perturbations observed by the S85-1 satellite in a circular sun-synchronous orbit near 200 km altitudes. The most obvious manifestations of the cells was the presence of density peaks located near 70{degrees}{Lambda} on the dayside and nightside, and a density minimum near the magnetic pole. Since high-latitude densities are generally expected to increase during magnetic activity, the low densities over the pole are perhaps the most interesting feature of the cell structure discussed here. The satellite data confirm the existence of the cellular structure over a range of magnetic activity levels. The discovery of the cells is important because the structure provides a unifying framework for the analysis and interpretation of high-latitude data from both past and future experiments. The cells result from various forms of coupling between the ionosphere and thermosphere. The cell formation is quantitatively consistent with concepts from dynamic meteorology. 34 refs., 11 figs.

  14. The chaos within: exploring noise in cellular biology

    E-Print Network [OSTI]

    Iain G. Johnston

    2012-08-10

    Cellular biology exists embedded in a world dominated by random dynamics and chance. Many vital molecules and pieces of cellular machinery diffuse within cells, moving along random trajectories as they collide with the other biomolecular inhabitants of the cell. Cellular components may block each other's progress, be produced or degraded at random times, and become unevenly separated as cells grow and divide. Cellular behaviour, including important features of stem cells, tumours and infectious bacteria, is profoundly influenced by the chaos which is the environment within the cell walls. Here we will look at some important causes and effects of randomness in cellular biology, and some ways in which researchers, helped by the vast amounts of data that are now flowing in, have made progress in describing the randomness of nature.

  15. Heterogeneous Force Chains in Cellularized Biopolymer Network

    E-Print Network [OSTI]

    Long Liang; Christopher Jones; Bo Sun; Yang Jiao

    2015-08-18

    Biopolymer Networks play an important role in coordinating and regulating collective cellular dynamics via a number of signaling pathways. Here, we investigate the mechanical response of a model biopolymer network due to the active contraction of embedded cells. Specifically, a graph (bond-node) model derived from confocal microscopy data is used to represent the network microstructure, and cell contraction is modeled by applying correlated displacements at specific nodes, representing the focal adhesion sites. A force-based stochastic relaxation method is employed to obtain force-balanced network under cell contraction. We find that the majority of the forces are carried by a small number of heterogeneous force chains emitted from the contracting cells. The force chains consist of fiber segments that either possess a high degree of alignment before cell contraction or are aligned due to the reorientation induced by cell contraction. Large fluctuations of the forces along different force chains are observed. Importantly, the decay of the forces along the force chains is significantly slower than the decay of radially averaged forces in the system. These results suggest that the fibrous nature of biopolymer network structure can support long-range force transmission and thus, long-range mechanical signaling between cells.

  16. Extracting Patterns from Location History Andrew Kirmse

    E-Print Network [OSTI]

    Cortes, Corinna

    " to infer the user's important locations. The "Place lab client" infers locations by listening to RF-emissions different modes of transportation (e.g. bus, on foot, car etc.). Both these papers use clean regularly-sampled

  17. Cell phones continue to be cited as causing fires at the pump in e-mails circulating on the Internet. So far we have been unable to document any incidents that were sparked by a cellular telephone.

    E-Print Network [OSTI]

    Jones, Thomas B.

    /STATEMENT OF THE PROBLEM: Until September, 1999, the only motor vehicle refueling fires that the Petroleum Equipment between the nozzle and the gasoline dispenser, or a spark from the engine compartment of a vehicle with its motor running. From September 1999 through January 22, 2000, 36 ignitions of gasoline vapors

  18. PROBABILISTIC METHODS FOR LOCATION ESTIMATION IN

    E-Print Network [OSTI]

    Myllymäki, Petri

    PROBABILISTIC METHODS FOR LOCATION ESTIMATION IN WIRELESS NETWORKS Petri Kontkanen, Petri Myllym;PROBABILISTIC METHODS FOR LOCATION ESTIMATION IN WIRELESS NETWORKS Petri Kontkanen, Petri Myllym¨aki, Teemu Roos METHODS FOR LOCATION ESTIMATION IN WIRELESS NETWORKS Petri Kontkanen, Petri Myllymäki, Teemu Roos, Henry

  19. The Cellular Mechanoresponse: Single-Cell Studies by Atomic Force Microscopy

    E-Print Network [OSTI]

    Crow, Alexis Kohnstamm

    2011-01-01

    L. (2008). Life and times of a cellular bleb. Biophys J 94,2007). Self?assembled cellular microarrays patterned usingand Ingber, D.  E. (2006). Cellular adaptation to mechanical

  20. Copper and Zinc Drive Inter-Domain Structure in the Cellular Prion Protein

    E-Print Network [OSTI]

    Evans, Eric Graham Burton

    2015-01-01

    C. (1986). Scrapie and cellular PrP isoforms are encoded byStrittmatter, S.M. (2009). Cellular prion protein mediatesW. , et al. (1997). The cellular prion protein binds copper

  1. Cellular mRNA decay protein AUF1 negatively regulates enterovirus and human rhinovirus infections

    E-Print Network [OSTI]

    Cathcart, AL; Rozovics, JM; Semler, BL

    2013-01-01

    N, Jackson RJ. 1999. unr, a cellular cytoplasmic RNA-bindingCellular mRNA Decay Protein AUF1 Negatively Regulatesof Print 31 July 2013. Cellular mRNA Decay Protein AUF1

  2. RESEARCH PAPER www.landesbioscience.com Cellular Logistics e29191-1

    E-Print Network [OSTI]

    Ungermann, Christian

    RESEARCH PAPER www.landesbioscience.com Cellular Logistics e29191-1 Cellular Logistics 4, e29191-specific HOPS subunits reveal their distinct interaction with Ypt7 and vacuoles. Cellular Logistics 2014; 4:e

  3. Metropolitan Community College (Missouri-all locations)

    E-Print Network [OSTI]

    - Choose one Core ECON 142 Princ of Microeconomics 3 ECON 210 Economics 3 GE3S ECON 144 Princ Prn Molecular/Cellular 5 No equivalent GE3N BIOL 152 Princ of Organismal Biology 5 No equivalent GE3N

  4. Picornaviruses and nuclear functions: Targeting a cellular compartment distinct from the replication site of a positive-strand RNA virus

    E-Print Network [OSTI]

    Flather, D; Semler, BL

    2015-01-01

    and Semler, B. L. (2013). Cellular mRNA decay protein AUF1pore complex: hijacking cellular phosphorylation machinery.2Apro expression on cellular metabolism. Inhibition of DNA

  5. Cellular Response to Ordered Collagen Layers on Mica 

    E-Print Network [OSTI]

    Leow, Wee Wen

    2012-07-16

    matrix with isotropic tensile strength to study cellular behaviors. 1. Assembly of unidirectionally aligned collagen layers on muscovite mica Muscovite mica is a phyllosilicate mineral of aluminium and potassium, with a com- mon chemical formula KAl2...

  6. BE.450 Molecular and Cellular Pathophysiology, Spring 2005

    E-Print Network [OSTI]

    Schauer, David

    This courses focuses on the fundamentals of tissue and organ response to injury from a molecular and cellular perspective. There is a special emphasis on disease states that bridge infection, inflammation, immunity, and ...

  7. Cellular responses against DNA damaged by platinum anticancer drugs

    E-Print Network [OSTI]

    Jung, Yongwon, 1977-

    2005-01-01

    The anticancer activity of platinum-based drugs such as cisplatin, carboplatin, and oxaliplatin is mediated by their ability to attack DNA such that generated adducts trigger numerous cellular responses. A better understanding ...

  8. Cellular Transport of Prostaglandins in the Ovine Uterus 

    E-Print Network [OSTI]

    Lee, Je Hoon

    2013-05-08

    by a PGT-mediated mechanism in sheep, new mechanistic insight into molecular mechanisms regulating cellular and compartmental transport of PGF2? at the time of luteolysis, and new mechanistic understanding of IFNT action and release of PGF2? from...

  9. A Lagrangian-Driven Cellular Automaton Supporting Quantum Field Theory

    E-Print Network [OSTI]

    Hans H. Diel

    2015-08-23

    Models of areas of physics in terms of cellular automata have become increasingly popular. Cellular automata (CAs) support the modeling of systems with discrete state component values and enforce the comprehensive specification of the dynamic evolution of such systems. Because many areas of physics can be described by starting with a specific Lagrangian, the idea to derive a cellular automaton directly from the Lagrangian (or similar construct, such as the Hamiltonian or action) is not new. Previous work, however, indicated that the classical CA may not be a sufficient basis for the modeling of more advanced physics theories, such as quantum field theory. Specifically, the modeling of interactions in quantum field theory requires extensions and modifications of the classical CA. This paper describes a proposal for an extended cellular automaton that is suited for support of quantum field theory.

  10. A Lagrangian-Driven Cellular Automaton Supporting Quantum Field Theory

    E-Print Network [OSTI]

    Diel, Hans H

    2015-01-01

    Models of areas of physics in terms of cellular automata have become increasingly popular. Cellular automata (CAs) support the modeling of systems with discrete state component values and enforce the comprehensive specification of the dynamic evolution of such systems. Because many areas of physics can be described by starting with a specific Lagrangian, the idea to derive a cellular automaton directly from the Lagrangian (or similar construct, such as the Hamiltonian or action) is not new. Previous work, however, indicated that the classical CA may not be a sufficient basis for the modeling of more advanced physics theories, such as quantum field theory. Specifically, the modeling of interactions in quantum field theory requires extensions and modifications of the classical CA. This paper describes a proposal for an extended cellular automaton that is suited for support of quantum field theory.

  11. Cellular and molecular correlates of neural morphallaxis in Lumbriculus variegatus 

    E-Print Network [OSTI]

    Martinez, Veronica Giselle

    2006-08-16

    Tissue regeneration has intrigued biologists since the eighteenth century. While regeneration has been studied in many species, the cellular and molecular mechanisms governing successful compensation for lost body parts are poorly defined...

  12. Cellular/Molecular Connexin35 Mediates Electrical Transmission at Mixed

    E-Print Network [OSTI]

    Rash, John E.

    Cellular/Molecular Connexin35 Mediates Electrical Transmission at Mixed Synapses on Mauthner Cells regions, suggesting that connexin35-mediated electrical transmission is common in goldfish brain" (electrical and chemical) synaptic terminals that offer the unique opportunity to correlate physiological

  13. Rapid and Precise Determination of Cellular Amino Acid Flux Rates

    E-Print Network [OSTI]

    Wikswo, John

    in hepa- tocyte and hepatoma cell lines where extensive gluconeogen- esis, urea production, and protein, therefore, can increase productivity compared to offline methods. Consistent automated OPARapid and Precise Determination of Cellular Amino Acid Flux Rates Using HPLC with Automated

  14. Cellular/Molecular Fast-Activating Voltage-and Calcium-Dependent Potassium

    E-Print Network [OSTI]

    Cellular/Molecular Fast-Activating Voltage- and Calcium-Dependent Potassium (BK) Conductance present in the cellular membrane. Experimental and computational approaches have revealed the dynamic

  15. Community Detection from Location-Tagged Networks

    E-Print Network [OSTI]

    Liu, Zhi

    2015-01-01

    Many real world systems or web services can be represented as a network such as social networks and transportation networks. In the past decade, many algorithms have been developed to detect the communities in a network using connections between nodes. However in many real world networks, the locations of nodes have great influence on the community structure. For example, in a social network, more connections are established between geographically proximate users. The impact of locations on community has not been fully investigated by the research literature. In this paper, we propose a community detection method which takes locations of nodes into consideration. The goal is to detect communities with both geographic proximity and network closeness. We analyze the distribution of the distances between connected and unconnected nodes to measure the influence of location on the network structure on two real location-tagged social networks. We propose a method to determine if a location-based community detection...

  16. Helicopter magnetic survey conducted to locate wells

    SciTech Connect (OSTI)

    Veloski, G.A.; Hammack, R.W.; Stamp, V.; Hall, R.; Colina, K.

    2008-07-01

    A helicopter magnetic survey was conducted in August 2007 over 15.6 sq mi at the Naval Petroleum Reserve No. 3’s (NPR-3) Teapot Dome Field near Casper, Wyoming. The survey’s purpose was to accurately locate wells drilled there during more than 90 years of continuous oilfield operation. The survey was conducted at low altitude and with closely spaced flight lines to improve the detection of wells with weak magnetic response and to increase the resolution of closely spaced wells. The survey was in preparation for a planned CO2 flood for EOR, which requires a complete well inventory with accurate locations for all existing wells. The magnetic survey was intended to locate wells missing from the well database and to provide accurate locations for all wells. The ability of the helicopter magnetic survey to accurately locate wells was accomplished by comparing airborne well picks with well locations from an intense ground search of a small test area.

  17. Earthquake locations and seismic velocity models for Southern California

    E-Print Network [OSTI]

    Lin, Guoqing

    2007-01-01

    Linearized EarthquakeChapter 4. The COMPLOC Earthquake Location3-D Simultaneous Earthquake Locations and

  18. Locating and tracking assets using RFID 

    E-Print Network [OSTI]

    Kim, Gak Gyu

    2009-05-15

    , this research presents a math¬ematical model of using RFID (both handheld readers and stationary readers) for e?cient asset location. We derive the expected cost of locating RFID¬tagged objects in a multi¬area environment where hand¬held RF readers are used. We...

  19. Implementing Per Bak's Sand Pile Model as a Two-Dimensional Cellular Automaton

    E-Print Network [OSTI]

    Tesfatsion, Leigh

    -dimensional cellular automaton (checkerboard model) · Pseudo-code description of Per Bak's sand pile model (Winslow

  20. Open cellular structure in marine stratocumulus sheets K. K. Comstock,1

    E-Print Network [OSTI]

    Bretherton, Chris

    Open cellular structure in marine stratocumulus sheets R. Wood,1 K. K. Comstock,1 C. S. Bretherton cellular structure in marine stratocumulus clouds over the southeast Pacific (SEP). Open cellular in the fractional coverage of open cellular convection over the broader SEP. This coverage is well correlated

  1. Real-Time Bioluminescent Tracking of Cellular Population Dynamics

    SciTech Connect (OSTI)

    Close, Dan; Sayler, Gary Steven; Xu, Tingting; Ripp, Steven Anthony

    2014-01-01

    Cellular population dynamics are routinely monitored across many diverse fields for a variety of purposes. In general, these dynamics are assayed either through the direct counting of cellular aliquots followed by extrapolation to the total population size, or through the monitoring of signal intensity from any number of externally stimulated reporter proteins. While both viable methods, here we describe a novel technique that allows for the automated, non-destructive tracking of cellular population dynamics in real-time. This method, which relies on the detection of a continuous bioluminescent signal produced through expression of the bacterial luciferase gene cassette, provides a low cost, low time-intensive means for generating additional data compared to alternative methods.

  2. Quantum Dot Spin Cellular Automata for Realizing a Quantum Processor

    E-Print Network [OSTI]

    Abolfazl Bayat; Charles E. Creffield; John H. Jefferson; Michael Pepper; Sougato Bose

    2015-09-09

    We show how "single" quantum dots, each hosting a singlet-triplet qubit, can be placed in arrays to build a spin quantum cellular automaton. A fast ($\\sim 10$ ns) deterministic coherent singlet-triplet filtering, as opposed to current incoherent tunneling/slow-adiabatic based quantum gates (operation time $\\sim 300$ ns), can be employed to produce a two-qubit gate through capacitive (electrostatic) coupling that can operate over significant distances. This is the coherent version of the widely discussed charge and nano-magnet cellular automata and would offer speed, reduce dissipation, perform quantum computation, while interfacing smoothly with its classical counterpart. This combines the best of two worlds -- the coherence of spin pairs known from quantum technologies, and the strength and range of electrostatic couplings from the charge based classical cellular automata.

  3. High-throughput screening for modulators of cellular contractile force

    E-Print Network [OSTI]

    Park, Chan Young; Tambe, Dhananjay; Chen, Bohao; Lavoie, Tera; Dowell, Maria; Simeonov, Anton; Maloney, David J; Marinkovic, Aleksandar; Tschumperlin, Daniel J; Burger, Stephanie; Frykenberg, Matthew; Butler, James P; Stamer, W Daniel; Johnson, Mark; Solway, Julian; Fredberg, Jeffrey J; Krishnan, Ramaswamy

    2014-01-01

    When cellular contractile forces are central to pathophysiology, these forces comprise a logical target of therapy. Nevertheless, existing high-throughput screens are limited to upstream signaling intermediates with poorly defined relationship to such a physiological endpoint. Using cellular force as the target, here we screened libraries to identify novel drug candidates in the case of human airway smooth muscle cells in the context of asthma, and also in the case of Schlemm's canal endothelial cells in the context of glaucoma. This approach identified several drug candidates for both asthma and glaucoma. We attained rates of 1000 compounds per screening day, thus establishing a force-based cellular platform for high-throughput drug discovery.

  4. The Construction of Locative Situations: Locative Media and the Situationist International, Recuperation or Redux?

    E-Print Network [OSTI]

    McGarrigle, Conor

    2009-01-01

    closely aligned to the SI's construction of situations. ThisG (1957) Report on the Construction of Situations and on theThe Construction of Locative Situations: Locative Media and

  5. Ratchet Cellular Automata for Colloids in Dynamic Traps

    E-Print Network [OSTI]

    C. J. Olson Reichhardt; C. Reichhardt

    2006-02-13

    We numerically investigate the transport of kinks in a ratchet cellular automata geometry for colloids interacting with dynamical traps. We find that thermal effects can enhance the transport efficiency in agreement with recent experiments. At high temperatures we observe the creation and annihilation of thermally induced kinks that degrade the signal transmission. We consider both the deterministic and stochastic cases and show how the trap geometry can be adjusted to switch between these two cases. The operation of the dynamical trap geometry can be achieved with the adjustment of fewer parameters than ratchet cellular automata constructed using static traps.

  6. Method of locating underground mines fires

    DOE Patents [OSTI]

    Laage, Linneas (Eagam, MN); Pomroy, William (St. Paul, MN)

    1992-01-01

    An improved method of locating an underground mine fire by comparing the pattern of measured combustion product arrival times at detector locations with a real time computer-generated array of simulated patterns. A number of electronic fire detection devices are linked thru telemetry to a control station on the surface. The mine's ventilation is modeled on a digital computer using network analysis software. The time reguired to locate a fire consists of the time required to model the mines' ventilation, generate the arrival time array, scan the array, and to match measured arrival time patterns to the simulated patterns.

  7. Earthquake Location, Direct, Global-Search Methods E 2449 Earthquake Location,

    E-Print Network [OSTI]

    Earthquake Location, Direct, Global-Search Methods E 2449 Earthquake Location, Direct, Global Kingdom Article Outline Glossary Definition of the Subject Introduction The Earthquake Location Problem or temporal av- erage of some characteristic of an earthquake, such as surface shaking intensity or moment

  8. Addressing endogeneity in residential location models

    E-Print Network [OSTI]

    Guevara-Cue, Cristián Angelo

    2005-01-01

    Some empirical residential location choice models have reported dwelling-unit price estimated parameters that are small, not statistically significant, or even positive. This would imply that households are non-sensitive ...

  9. Techniques for Mobile Location Estimation in UMTS 

    E-Print Network [OSTI]

    Thomas, Nicholas J

    The subject area of this thesis is the locating of mobile users using the future 3rd generation spread spectrum communication system UMTS. The motivation behind this work is twofold: firstly the United States Federal ...

  10. A Survey on the Warehouse Location Problem

    E-Print Network [OSTI]

    Cohen, Joseph J.

    The warehouse location problem has assumed numerous formulations, and solutions have been devised using a variety of mathematical techniques. The development of this effort is examined and relevant models presented for evaluation.

  11. Developing a theory of nightclub location choice

    E-Print Network [OSTI]

    Crim, Stephen J. (Stephen Johnson)

    2008-01-01

    This work is an investigation of the factors that influence where nightclubs locate within a city. Nightclubs, like other social spaces, provide important social and economic benefits in the urban environment. As amenities, ...

  12. Alternative Fuel Infrastructure Associate Location: San Diego

    E-Print Network [OSTI]

    California at Davis, University of

    Alternative Fuel Infrastructure Associate Location: San Diego Basic Functions Center an Alternative Fuel Infrastructure Associate that has a passion for sustainability, the environment, and accelerating the transition to a sustainable world powered by clean energy! The Alternative Fuel Infrastructure

  13. Driver expectancy in locating automotive controls 

    E-Print Network [OSTI]

    Francis, Dawn Suzette

    1990-01-01

    DRIVER EXPECTANCY IN LOCATING AUTOMOTIVE CONTROLS A Thesis by DAWN SUZETTE FRANCIS Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE May 1990... Major Subject: Industrial Engineering DRIVER EXPECTANCY IN LOCATING AUTOMOTIVE CONTROLS A Thesis by DAWN SUZETTE FRANCIS Approved as to style and content by: R. Dale Huchi son (Chair of Committee) Rodger . . ppa (Member) Waymon L ohnston (M er...

  14. Cellular/Molecular Spine Neck Plasticity Controls Postsynaptic Calcium Signals

    E-Print Network [OSTI]

    Oertner, Thomas

    as active electrical amplifiers (Segev and Rall, 1988). According to this theory, active spines couldCellular/Molecular Spine Neck Plasticity Controls Postsynaptic Calcium Signals through Electrical been proposed to function as electrical compartments for the active processing of local synaptic

  15. Identifying Important Places in People's Lives from Cellular Network Data

    E-Print Network [OSTI]

    Singh, Jaswinder Pal

    derived from government census data. Finally, we perform carbon footprint analyses on hundreds move about would help determine their carbon footprint and in turn help guide policies intended to reduce that footprint. Wireless cellular networks hold great potential for providing the necessary infor

  16. Quantum-Dot Cellular Automata SPICE Macro Model Northeastern University

    E-Print Network [OSTI]

    Ayers, Joseph

    and majority voter. A full-adder is designed with QCA cells using the SPICE model as a test vehicle describes a SPICE model development method- ology for Quantum-Dot Cellular Automata (QCA) cells and presents a SPICE model for QCA cells. The model is val- idated by simulating the basic logic gates such as inverter

  17. BIOLOGICAL FRAMEWORKS FOR ENGINEERS Session #14 [Cellular Energetics

    E-Print Network [OSTI]

    Sniadecki, Nathan J.

    of chemical bonds into free energy for the cell to utilize; nature's storage and handling of energy may provide insight into our engineering of energy solutions Interactive Activity: Discussions on cellular processes to produce energy efficiently. Session Outline: A. Basics of Energy 1. Thermodynamics

  18. Spatial Outage Probability for Cellular Networks Jean-Marc Kelif

    E-Print Network [OSTI]

    Coupechoux, Marceau

    Spatial Outage Probability for Cellular Networks Jean-Marc Kelif France Telecom R&D Issy networks called the fluid model and we derive from this model analytical formulas for interference, outage probability, and spatial outage probability. The key idea of the fluid model is to consider the discrete base

  19. Cellular mechanisms of membrane protein folding William R Skach

    E-Print Network [OSTI]

    Cai, Long

    Cellular mechanisms of membrane protein folding William R Skach The membrane protein­folding. This Perspective will focus on emerging evidence that the RTC functions as a protein-folding machine that restricts. The process of polytopic (multispanning) membrane protein folding can be viewed as a series of sequential

  20. Hyperbolic Real Quadratic Cellular Automata J. Delgado1

    E-Print Network [OSTI]

    are hyperbolic for large values of the parameter. Keywords. Hyperbolicity. -limit set. Lattice Dynamical Systems systems generated by a group of spatial translations : M M, x = {x} (x) = {x }, that is ((x)) = x , #12. In [11] real cellular automata appear to describe bifurcations of coupled logistic map together a linear

  1. Optimal Base Station Density for Power Efficiency in Cellular Networks

    E-Print Network [OSTI]

    Haenggi, Martin

    Optimal Base Station Density for Power Efficiency in Cellular Networks Sanglap Sarkar, Radha, power consumption, power efficiency, optimal base station density. I. INTRODUCTION Cell size reduction by increasing the number of macro base stations or adding tiers of low powered base stations. There are two

  2. NHLBI Workshop Summaries Resident Cellular Components of the Human Lung

    E-Print Network [OSTI]

    Engelhardt, John F.

    NHLBI Workshop Summaries Resident Cellular Components of the Human Lung Current Knowledge and Goals, Maryland; 5 Lung Diseases, National Heart, Lung and Blood Institute, National Institutes of Health and Cell Biology, The University of Iowa, Iowa City, Iowa; 11 Developmental Lung Biology Research

  3. Graphene and Nanowire Transistors for Cellular Interfaces and Electrical Recording

    E-Print Network [OSTI]

    Xie, Xiaoliang Sunney

    Graphene and Nanowire Transistors for Cellular Interfaces and Electrical Recording Tzahi Cohen interfaces with cell membranes. Graphene has also been shown to be an attractive building block for nanoscale the first studies of graphene field effect transistors (Gra-FETs) as well as combined Gra- and NW

  4. Modeling triblock surfactant-templated mesostructured cellular foams Supriyo Bhattacharyaa

    E-Print Network [OSTI]

    Bhattacharya, Supriyo

    to understand the role of surfactant self-assembly in the synthesis of templated mesoporous materials, and inorganic oxide. Depending on the temperature and component concentrations, these systems phase separate to sphere transition associated with the synthesis of the mesostructured cellular foams MCFs . Pore size

  5. Mobility Management in Cellular Telephony Benjamin P. Cooke

    E-Print Network [OSTI]

    Mobility Management in Cellular Telephony Benjamin P. Cooke , Darongsae Kwon , Dmitry Glotov. The left hand side of each inequality (5) is composed of the load resulting from hand-offs within a controller, from a controller, and to a controller. Here, q represents the load from handing over a call

  6. Cellular Automata Simulation of the Spatial Conformations of Polyelectrolytes

    E-Print Network [OSTI]

    C. Echeverria; W. Olivares-Rivas; K. Tucci

    2006-12-04

    We carried out a Cellular Automata simulation of a model polyelectrolyte solution at infinite dilution, in order to reproduce qualitatively its conformational properties. Our results predict the so called \\emph{pearl necklace} structures, which compare favorably with the more elaborated and costly Molecular Dynamics simulations.

  7. Location theory and the location of industry along an interstate highway 

    E-Print Network [OSTI]

    Miller, James Patterson

    1965-01-01

    a greater gamble. This sect. ion has been devoted to s review of the fundamental factors underlying all plant location ss recognised in location theory. The next section will review some recent. empirical attempts to determine the actual... for this thesis was possible through the assistance provided )ointly by the Texas Highway Department and the Bureau of Public Roads. i. v TABLE OF CONTENTS Chapter Page INTRODUCTION Purpose Plan of Study REVIEW OF PLANT LOCATION CONCEPTS Introduction...

  8. Utility Locating in the DOE Environment

    SciTech Connect (OSTI)

    Clark Scott; Gail Heath

    2006-04-01

    Some advances have been made in utility locating in recent years and standards have been recently published to try and categorize the level of information known about the utility in the subsurface. At the same time some characterization about the level of effort or technology in the geophysicist approach to utility locating may be generalized. The DOE environment poses some added difficulties and this presentation covers these issues, costs and the technical approach that has been developed at the INEEL to prevent utility hits and how it fits into the generalized classification of effort.

  9. Regulating the cellular economy of supply and demand Jan-Hendrik S. HofmeyraY

    E-Print Network [OSTI]

    Minireview Regulating the cellular economy of supply and demand Jan-Hendrik S. HofmeyraY *, Athel March 2000 Edited by Gunnar von Heijne Abstract Cellular metabolism is a molecular economy

  10. Replacing cellular with WiFi direct communication for a highly interactive, high bandwidth multiplayer game

    E-Print Network [OSTI]

    Ortiz, Pablo (Pablo Jose)

    2013-01-01

    The objective of this work is to explore the benefits of replacing cellular with Wi-Fi Direct communication in mobile applications. Cellular connections consume significant power on mobile devices and are too slow for many ...

  11. Lorentz symmetry for 3d Quantum Cellular Automata

    E-Print Network [OSTI]

    Alessandro Bisio; Giacomo Mauro D'Ariano; Paolo Perinotti

    2015-03-03

    We introduce a definition of Lorentz transformations in the framework of quantum cellular automata. Our definition does not require space-time, and retains the usual interpretation in the emergent one. The definition is group theoretical, with flatness of space-time corresponding to Abelianity of the cellular automaton group. We consider the covariance in the case of the Weyl automaton. The notion of particle as Poincar\\'e irreducible representation survives at all scales. The interpolation of the Lorentz symmetry from the discrete to the continuum scale occurs through a nonlinear representation. We also discuss the connection of the nonlinear Lorentz transformations with the Poincar\\'e and k-Poincar\\'e Hopf algebra, the emerging non-commutative space-time, and the deformed Heisenberg commutation relations.

  12. Quantum State Transfer through Noisy Quantum Cellular Automata

    E-Print Network [OSTI]

    Michele Avalle; Marco G. Genoni; Alessio Serafini

    2015-04-22

    We model the transport of an unknown quantum state on one dimensional qubit lattices by means of a quantum cellular automata evolution. We do this by first introducing a class of discrete noisy dynamics, in the first excitation sector, in which a wide group of classical stochastic dynamics is embedded within the more general formalism of quantum operations. We then extend the Hilbert space of the system to accommodate a global vacuum state, thus allowing for the transport of initial on-site coherences besides excitations, and determine the dynamical constraints that define the class of noisy quantum cellular automata in this subspace. We then study the transport performance through numerical simulations, showing that for some instances of the dynamics perfect quantum state transfer is attainable. Our approach provides one with a natural description of both unitary and open quantum evolutions, where the homogeneity and locality of interactions allow one to take into account several forms of quantum noise in a plausible scenario.

  13. Sustainable Transportation Fellowship Location: San Diego, CA

    E-Print Network [OSTI]

    California at Davis, University of

    Sustainable Transportation Fellowship Location: San Diego, CA Our clean energy future depends. · Regular web posts on other clean transportation topics. · Assist in other tasks, as assigned. The ideal and a clean, healthy environment. To bring about such a future, each of us must make wise choices now

  14. Secure Location Verification Using Radio Broadcast

    E-Print Network [OSTI]

    Nesterenko, Mikhail

    , exploits the difference between propagation speeds of radio and sound waves to estimate the position1 Secure Location Verification Using Radio Broadcast Adnan Vora and Mikhail Nesterenko Abstract of the prover. In this paper, we propose a solution that leverages the broadcast nature of the radio signal

  15. Secure Location Verification Using Radio Broadcast

    E-Print Network [OSTI]

    Nesterenko, Mikhail

    the difference between propagation speeds of radio and sound waves to estimate the position of the proverSecure Location Verification Using Radio Broadcast Adnan Vora and Mikhail Nesterenko Computer. In this paper, we propose a solution that leverages the broadcast nature of the radio signal emitted

  16. OPTIMAL LOCATION OF ISOLATION VALVES IN WATER

    E-Print Network [OSTI]

    Mays, Larry W.

    CHAPTER 7 OPTIMAL LOCATION OF ISOLATION VALVES IN WATER DISTRIBUTION SYSTEMS: A RELIABILITY The cornerstone of any healthy population is access to safe drinking water. The goal of the United Nations International Drinking Water Supply and Sanitation Decade from 1981 to 1990 was safe drinking water for all

  17. Ontology-based Disambiguation of Spatiotemporal Locations

    E-Print Network [OSTI]

    Hyvönen, Eero

    , in the semantic portal MuseumFinland3 [7] a location parton- omy4 was used for annotating museum artifacts. #12;A problem when creating a semantic cultural heritage portal is that places, both modernFinland originate from regions that no longer exist and/or are not part of Finland but of Russia with new names

  18. Locating Secret Messages in Images Ian Davidson

    E-Print Network [OSTI]

    Davidson, Ian

    Locating Secret Messages in Images Ian Davidson Computer Science, SUNY Albany 1400 Washington in innocuous media such as images, while steganalysis is the field of detecting these secret messages contributing the most to the energy calculations of an image are deemed outliers. Typically, of the top third

  19. www.elsevier.com/locate/visres polarization

    E-Print Network [OSTI]

    Boal, Jean

    .elsevier.com/locate/visres Cuttlefish use polarization sensitivity in predation on silvery fish Nadav Shashar a,b, Roland Hagan c, Jean of cuttlefish, we examined the preference of Sepia officina/is when presented with fish whose polarization reflection was greatly reduced versus fish whose polarization reflection was not affected. Cuttlefish preyed

  20. Postal address School of Industrial Design, LTH, P.O. Box 118, 221 00 Lund, SWEDEN Telephone +46 46 222 71 88 E-mail Lynn.Lindegren@kansli.lth.se Website www.industrialdesign.lth.se

    E-Print Network [OSTI]

    Postal address School of Industrial Design, LTH, P.O. Box 118, 221 00 Lund, SWEDEN Telephone +46 46 222 71 88 E-mail Lynn.Lindegren@kansli.lth.se Website www.industrialdesign.lth.se School of Industrial of Industrial Design autumn semester 2015. Full-time study is 30 credits. Bachelor´s programme ­ 1st term Course

  1. The cellular role of the specific immune system in fracture repair 

    E-Print Network [OSTI]

    Gaston, Mark S

    2009-01-01

    This thesis embodies a novel investigation into the cellular role of the specific immune system in fracture repair....

  2. Cellular growth and division in the Gillespie , Dmitri Volfson2,3

    E-Print Network [OSTI]

    Tsimring, Lev S.

    1 Cellular growth and division in the Gillespie algorithm Ting Lu1 , Dmitri Volfson2,3 , Lev of the cellular volume, and demonstrate that a careful rederivation of the Gillespie algorithm is important when all stochastically simulated reactions have rates slower or comparable to the cellular growth rate

  3. Cellular growth and division in the Gillespie T. Lu, D. Volfson, L. Tsimring and J. Hasty

    E-Print Network [OSTI]

    Hasty, Jeff

    Cellular growth and division in the Gillespie algorithm T. Lu, D. Volfson, L. Tsimring and J. Hasty of growth and division of the cellular volume, and demonstrate that a careful re-derivation of the Gillespie to the cellular growth rate. For an unregulated single-gene system, we illustrate our findings using recently

  4. CELLULAR AUTOMATA BASED CRYPTOSYSTEM Subhayan Sen 1 Chandrama Shaw 1 Dipanwita Roy Chowdhuri 2

    E-Print Network [OSTI]

    Ganguly, Niloy

    CELLULAR AUTOMATA BASED CRYPTOSYSTEM (CAC) Subhayan Sen 1 Chandrama Shaw 1 Dipanwita Roy Chowdhuri introduces a Cellular Automata (CA) based sym- metric key cryptosystem for block cipher. The scheme named as CAC (Cellular Automata based Cryptosystem) employs a series of transforms { simple, moderately complex

  5. Cellular metal lattices with hollow trusses Douglas T. Queheillalt *, Haydn N.G. Wadley

    E-Print Network [OSTI]

    Wadley, Haydn

    Cellular metal lattices with hollow trusses Douglas T. Queheillalt *, Haydn N.G. Wadley Department; accepted 21 September 2004 Available online 22 October 2004 Abstract Cellular metal lattice truss to buckling offsetting the usually rapid drop in strength as the relative density decreases in cellular

  6. CELLULAR FOAMS: A POTENTIAL INNOVATIVE SOLID BREEDER MATERIAL FOR FUSION APPLICATIONS

    E-Print Network [OSTI]

    Ghoniem, Nasr M.

    CELLULAR FOAMS: A POTENTIAL INNOVATIVE SOLID BREEDER MATERIAL FOR FUSION APPLICATIONS S. Sharafat-1597; shahrams@ucla.edu Ultramet Inc., Pacoima CA, Pacoima CA 91331-2210 Ceramic foam and cellular materials the past decade advances in manufacturing of cellular materials have resulted in ceramics with highly

  7. CELLULAR AUTOMATA MODELS AND MHD APPROACH IN THE CONTEXT OF SOLAR FLARES 1

    E-Print Network [OSTI]

    Anastasiadis, Anastasios

    CELLULAR AUTOMATA MODELS AND MHD APPROACH IN THE CONTEXT OF SOLAR FLARES 1 Anastasios Anastasiadis anastasi@space.noa.gr Abstract: We address in detail the cellular automaton approach, developed be used. These types of mathematical tools are the Automata and the Cellular Automata (CA). The advantage

  8. Case: Cellular phones Authors: Michael Hamid, Jose de Jesus Rodriguez, Nicole Trahan

    E-Print Network [OSTI]

    Williams, John M.

    Case: Cellular phones Authors: Michael Hamid, Jose de Jesus Rodriguez, Nicole Trahan Suggested Courses: Antenna Thy/Des Level: Junior I. Narrative Cellular phones are one of the most popular items signals in the 800 MHz band and up to and beyond a 30 mile radius. Lately cellular phones have been

  9. Cellular Data Network Infrastructure Characterization and Implication on Mobile Content Placement

    E-Print Network [OSTI]

    Mao, Zhuoqing Morley

    Cellular Data Network Infrastructure Characterization and Implication on Mobile Content Placement@eecs.umich.edu ABSTRACT Despite the tremendous growth in the cellular data network usage due to the popularity of smartphones, so far there is rather lim- ited understanding of the network infrastructure of various cellular

  10. Cellular Responses in Sea Fan Corals: Granular Amoebocytes React to Pathogen and Climate Stressors

    E-Print Network [OSTI]

    Harvell, Catherine Drew

    Cellular Responses in Sea Fan Corals: Granular Amoebocytes React to Pathogen and Climate Stressors amoebocyte responses indicate that sea fan corals use cellular defenses to combat fungal infection SF, Peters EC, Harvell CD (2008) Cellular Responses in Sea Fan Corals: Granular Amoebocytes React

  11. Cellular Patterns in the Inner Retina of Adult Zebrafish: Quantitative Analyses

    E-Print Network [OSTI]

    Carney, Laurel H.

    Cellular Patterns in the Inner Retina of Adult Zebrafish: Quantitative Analyses and a Computational 13244 ABSTRACT The mechanisms that control cellular pattern formation in the growing vertebrate central nervous system are poorly understood. In an effort to reveal mechanistic rules of cellular pattern

  12. Cellular metals Anthony G Evans*, John W Hutchinson* and Michael F Ashby?

    E-Print Network [OSTI]

    Hutchinson, John W.

    233 Cellular metals Anthony G Evans*, John W Hutchinson* and Michael F Ashby? The property profile exhibited by cellular metals identifies several applications, especially in technologies requiring the properties that govern these performance benefits and the cellular architecture, cell morphology and density

  13. Special issue CellBio-X Engineered materials and the cellular

    E-Print Network [OSTI]

    Chen, Christopher S.

    Special issue ­ CellBio-X Engineered materials and the cellular microenvironment: a strengthening have elucidated the significance of the cellular microenvironment. Here, we highlight some of the major. In contrast, the current understand- ing of how insoluble cues, such as adhesion to the extra- cellular matrix

  14. EmergeNet: Robust, Rapidly Deployable Cellular Networks Daniel Iland and Elizabeth M. Belding

    E-Print Network [OSTI]

    Belding-Royer, Elizabeth M.

    . Keywords-Cellular networks, community cellular networks, emergency networks, GSM, solar energy, wireless deployable, small scale cellular network. In this article, we describe EmergeNet, which addresses high load, limited bandwidth, and software or hardware failures. EmergeNet is uniquely well suited

  15. Oscillatory cellular patterns in three-dimensional directional solidification

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Tourret, D.; Debierre, J. -M.; Song, Y.; Mota, F. L.; Bergeon, N.; Guerin, R.; Trivedi, R.; Billia, B.; Karma, A.

    2015-09-11

    We present a phase-field study of oscillatory breathing modes observed during the solidification of three-dimensional cellular arrays in micro-gravity. Directional solidification experiments conducted onboard the International Space Station have allowed for the first time to observe spatially extended homogeneous arrays of cells and dendrites while minimizing the amount of gravity-induced convection in the liquid. In situ observations of transparent alloys have revealed the existence, over a narrow range of control parameters, of oscillations in cellular arrays with a period ranging from about 25 to 125 minutes. Cellular patterns are spatially disordered, and the oscillations of individual cells are spatiotemporally uncorrelatedmore »at long distance. However, in regions displaying short-range spatial ordering, groups of cells can synchronize into oscillatory breathing modes. Quantitative phase-field simulations show that the oscillatory behavior of cells in this regime is linked to a stability limit of the spacing in hexagonal cellular array structures. For relatively high cellular front undercooling (\\ie low growth velocity or high thermal gradient), a gap appears in the otherwise continuous range of stable array spacings. Close to this gap, a sustained oscillatory regime appears with a period that compares quantitatively well with experiment. For control parameters where this gap exist, oscillations typically occur for spacings at the edge of the gap. However, after a change of growth conditions, oscillations can also occur for nearby values of control parameters where this gap just closes and a continuous range of spacings exists. In addition, sustained oscillations at to the opening of this stable gap exhibit a slow periodic modulation of the phase-shift among cells with a slower period of several hours. While long-range coherence of breathing modes can be achieved in simulations for a perfect spatial arrangement of cells as initial condition, global disorder is observed in both three-dimensional experiments and simulations from realistic noisy initial conditions. The, erratic tip splitting events promoted by large amplitude oscillations contribute to maintaining the long-range array disorder, unlike in thin sample experiments where long-range coherence of oscillations is experimentally observable.« less

  16. Mobile Homophily and Social Location Prediction

    E-Print Network [OSTI]

    Bapierre, Halgurt; Groh, Georg

    2015-01-01

    The mobility behavior of human beings is predictable to a varying degree e.g. depending on the traits of their personality such as the trait extraversion - introversion: the mobility of introvert users may be more dominated by routines and habitual movement patterns, resulting in a more predictable mobility behavior on the basis of their own location history while, in contrast, extrovert users get about a lot and are explorative by nature, which may hamper the prediction of their mobility. However, socially more active and extrovert users meet more people and share information, experiences, believes, thoughts etc. with others. which in turn leads to a high interdependency between their mobility and social lives. Using a large LBSN dataset, his paper investigates the interdependency between human mobility and social proximity, the influence of social networks on enhancing location prediction of an individual and the transmission of social trends/influences within social networks.

  17. VCSEL fault location apparatus and method

    DOE Patents [OSTI]

    Keeler, Gordon A. (Albuquerque, NM); Serkland, Darwin K. (Albuquerque, NM)

    2007-05-15

    An apparatus for locating a fault within an optical fiber is disclosed. The apparatus, which can be formed as a part of a fiber-optic transmitter or as a stand-alone instrument, utilizes a vertical-cavity surface-emitting laser (VCSEL) to generate a test pulse of light which is coupled into an optical fiber under test. The VCSEL is subsequently reconfigured by changing a bias voltage thereto and is used as a resonant-cavity photodetector (RCPD) to detect a portion of the test light pulse which is reflected or scattered from any fault within the optical fiber. A time interval .DELTA.t between an instant in time when the test light pulse is generated and the time the reflected or scattered portion is detected can then be used to determine the location of the fault within the optical fiber.

  18. Menstrual cycle effects on spatial location tasks 

    E-Print Network [OSTI]

    Andrew, Sarah

    2013-02-22

    abilities (Halpem, 1992; Voyer et al. , 1995). However, there is one spatial ability test where women demonstrate an advantage over men. This female advantage spatial ability is known as spaflal location memory (Eals & Silvermen, 1994; Silverman & Eals..., Mock & Erbaugh, 1961) and a brief daily diary, which recorded subjective moods (i. e. , anxiety, sadness, anger, happiness, and energy level). The participants recorded their daily moods in the daily diary by marking a spot on a 10 cm visual analogue...

  19. Alternative Fueling Station Locator | Department of Energy

    Energy Savers [EERE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And StatisticsProgram ManagerCorridor Designations in 11Alternative Fueling Station Locator

  20. Location of Narrowband Spikes in Solar Flares

    E-Print Network [OSTI]

    Arnold O. Benz; Pascal Saint-Hilaire; Nicole Vilmer

    2001-12-19

    Narrowband spikes of the decimeter type have been identified in dynamic spectrograms of Phoenix-2 of ETH Zurich and located in position with the Nancay Radioheliograph at the same frequency. The spike positions have been compared with the location of hard X-ray emission and the thermal flare plasma in soft X-rays and EUV lines. The decimetric spikes are found to be single sources located some 20" to 400" away from the flare site in hard or soft X-rays. In most cases there is no bright footpoint nearby. In at least two cases the spikes are near loop tops. These observations do not confirm the widely held view that the spike emission is produced by some loss-cone instability masering near the footpoints of flare loops. On the other hand, the large distance to the flare sites and the fact that these spikes are all observed in the flare decay phase make the analyzed spike sources questionable sites for the main flare electron acceleration. They possibly indicate coronal post-flare acceleration sites.

  1. Semantics of Functional and Locative Relations in Rongga

    E-Print Network [OSTI]

    Aryawibawa, I. Nyoman

    2010-01-01

    Many scholars have proposed a universal set of locative relations. Herskovits’s comprehensive study of English locative relations found that locative concepts such as inclusion, support and contiguity, and coincidence are basic in English. Her...

  2. Location Prediction in Social Media Based on Tie Strength 

    E-Print Network [OSTI]

    McGee, Jeffrey A

    2013-04-29

    We propose a novel network-based approach for location estimation in social media that integrates evidence of the social tie strength between users for improved location estimation. Concretely, we propose a location estimator – Friendly...

  3. Energy Department Announces Student Teams, Location for Solar...

    Office of Environmental Management (EM)

    Student Teams, Location for Solar Decathlon 2015 Energy Department Announces Student Teams, Location for Solar Decathlon 2015 February 13, 2014 - 1:00pm Addthis News Media Contact...

  4. Optimization Online - p-facility Huff location problem on networks

    E-Print Network [OSTI]

    Rafael Blanquero

    2014-10-30

    Oct 30, 2014 ... Abstract: The p-facility Huff location problem aims at locating facilities on a competitive environment so as to maximize the market share.

  5. Research Site Locations for Current and Former EERE Postdoctoral...

    Broader source: Energy.gov (indexed) [DOE]

    Research Site Locations for Current and Former EERE Postdoctoral Awards, from the U.S. Department of Energy's Office of Energy Efficiency and Renewable Energy. Facility Location...

  6. Open Location-Oriented Services for the Web

    E-Print Network [OSTI]

    Wilde, Erik

    2008-01-01

    Location Management for Mobile Devices. In Proceedings ofof wireless data services and mobile devices can take fullof location-awareness and mobile devices. Conclusions This

  7. Investigation of Cellular Interactions of Nanoparticles by Helium Ion Microscopy

    SciTech Connect (OSTI)

    Arey, Bruce W.; Shutthanandan, V.; Xie, Yumei; Tolic, Ana; Williams, Nolann G.; Orr, Galya

    2011-06-01

    The helium ion mircroscope (HIM) probes light elements (e.g. C, N, O, P) with high contrast due to the large variation in secondary electron yield, which minimizes the necessity of specimen staining. A defining characteristic of HIM is its remarkable capability to neutralize charge by the implementation of an electron flood gun, which eliminates the need for coating non-conductive specimens for imaging at high resolution. In addition, the small convergence angle in HeIM offers a large depth of field (~5x FE-SEM), enabling tall structures to be viewed in focus within a single image. Taking advantage of these capabilities, we investigate the interactions of engineered nanoparticles (NPs) at the surface of alveolar type II epithelial cells grown at the air-liquid interface (ALI). The increasing use of nanomaterials in a wide range of commercial applications has the potential to increase human exposure to these materials, but the impact of such exposure on human health is still unclear. One of the main routs of exposure is the respiratory tract, where alveolar epithelial cells present a vulnerable target at the interface with ambient air. Since the cellular interactions of NPs govern the cellular response and ultimately determine the impact on human health, our studies will help delineating relationships between particle properties and cellular interactions and response to better evaluate NP toxicity or biocompatibility. The Rutherford backscattered ion (RBI) is a helium ions imaging mode, which backscatters helium ions from every element except hydrogen, with a backscatter yield that depends on the atomic number of the target. Energy-sensitive backscatter analysis is being developed, which when combined with RBI image information, supports elemental identification at helium ion nanometer resolution. This capability will enable distinguishing NPs from cell surface structures with nanometer resolution.

  8. A solar cellular automata model based on reduced MHD

    E-Print Network [OSTI]

    Buchlin, E; Galtier, S; Velli, M; Einaudi, G; Vial, J C

    2003-01-01

    A 3D cellular automata (CA) model inspired by the reduced magnetohydrodynamic (RMHD) equations is presented to simulate solar impulsive events generated along a coronal magnetic loop. The CA model consists of a set of planes distributed along a magnetic loop between which the information propagates through Alfven waves. Statistical properties in terms of power-laws for energies and durations of dissipative events are obtained, in agreement with X-ray and UV flares observations. The possible existence of observational biases is discussed.

  9. An intelligent floor field cellular automata model for pedestrian dynamics

    E-Print Network [OSTI]

    Ekaterina Kirik; Tat'yana Yurgel'yan; Dmitriy Krouglov

    2009-06-15

    A stochastic cellular automata (CA) model for pedestrian dynamics is presented. Our goal is to simulate different types of pedestrian movement, from regular to panic. But here we emphasize regular situations which imply that pedestrians analyze environment and choose their route more carefully. And transition probabilities have to depict such effect. The potentials of floor fields and environment analysis are combined in the model obtained. People patience is included in the model. This makes simulation of pedestrians movement more realistic. Some simulation results are presented and comparison with basic FF-model is made.

  10. Tel: Name: Rm. Tel: Location: Rm.

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home RoomPreservationBio-Inspired Solar FuelTechnologyTel: Name: Rm. Tel: Location: Rm. Oct 2, 2015 Amin,

  11. Sandia National Laboratories: Locations: Kauai Test Facility

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home RoomPreservation ofAlbuquerque Albuquerque Housing Education Recreation Locations LifeKauai Test

  12. Sandia National Laboratories: Locations: Livermore, California

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home RoomPreservation ofAlbuquerque Albuquerque Housing Education Recreation Locations LifeKauai

  13. Dirac Quantum Cellular Automaton from Split-step Quantum Walk

    E-Print Network [OSTI]

    Mallick, Arindam

    2015-01-01

    Simulations of one quantum system by an other has an implications in realization of quantum machine that can imitate any quantum systems and solve problems that are not accessible to classical computers. One of the approach to engineer quantum simulations is to discretize the space-time degree of freedom in quantum dynamics and define the quantum cellular automata (QCA), a local unitary update rule on a lattice. Different models of QCA are constructed using different set of conditions which are not uniquely defined. The form of the operators in these model are not always in implementable configuration on an other system. Here, starting from a split-step discrete-time quantum walk (DTQW) which are uniquely defined for experimental implementation, we recover the Dirac quantum cellular automaton (DQCA). This will bridge the connection between Dirac equation(DE)-DQCA-DTQW and eliminate the explicit use of invariance, symmetries and limiting range of parameter to establish the connections. For a combination of par...

  14. An Energy Efficient Location Service for Mobile Ad Hoc etworks

    E-Print Network [OSTI]

    Varela, Carlos

    the distance traveled by the location update and query packets and, thus, at reducing the overall energy cost by the location update and query packets and, thus, to reduce the overall energy cost. 2 Energy Efficient LocationAn Energy Efficient Location Service for Mobile Ad Hoc etworks Zijian Wang1 , Eyuphan Bulut1

  15. Locating hardware faults in a parallel computer

    DOE Patents [OSTI]

    Archer, Charles J.; Megerian, Mark G.; Ratterman, Joseph D.; Smith, Brian E.

    2010-04-13

    Locating hardware faults in a parallel computer, including defining within a tree network of the parallel computer two or more sets of non-overlapping test levels of compute nodes of the network that together include all the data communications links of the network, each non-overlapping test level comprising two or more adjacent tiers of the tree; defining test cells within each non-overlapping test level, each test cell comprising a subtree of the tree including a subtree root compute node and all descendant compute nodes of the subtree root compute node within a non-overlapping test level; performing, separately on each set of non-overlapping test levels, an uplink test on all test cells in a set of non-overlapping test levels; and performing, separately from the uplink tests and separately on each set of non-overlapping test levels, a downlink test on all test cells in a set of non-overlapping test levels.

  16. Location Independent Professional Project: A Pilot Study

    SciTech Connect (OSTI)

    Hudson, J.A.; Long, J.P.; Miller, M.M.

    1999-02-01

    This pilot study project explored the problem of providing access to the nomadic worker who desires to connect a computer through network access points at a number of different locations within the SNL/NM campus as well as outside the campus. The design and prototype development gathered knowledge that may allow a design to be developed that could be extended to a larger number of SNL/NM network drop boxes. The focus was to provide a capability for a worker to access the SNL IRN from a network drop box (e.g. in a conference room) as easily as when accessing the computer network from the office normally used by the worker. Additional study was done on new methods to authenticate the off campus worker, and protect and control access to data.

  17. Cell division: a source of active stress in cellular monolayers

    E-Print Network [OSTI]

    Doostmohammadi, Amin; Saw, Thuan B; Lim, Chwee T; Ladoux, Benoit; Yeomans, Julia M

    2015-01-01

    We introduce the notion of cell division-induced activity and show that the cell division generates extensile forces and drives dynamical patterns in cell assemblies. Extending the hydrodynamic models of lyotropic active nematics we describe turbulent-like velocity fields that are generated by the cell division in a confluent monolayer of cells. We show that the experimentally measured flow field of dividing Madin-Darby Canine Kidney (MDCK) cells is reproduced by our modeling approach. Division-induced activity acts together with intrinsic activity of the cells in extensile and contractile cell assemblies to change the flow and director patterns and the density of topological defects. Finally we model the evolution of the boundary of a cellular colony and compare the fingering instabilities induced by cell division to experimental observations on the expansion of MDCK cell cultures.

  18. Are nonlinear discrete cellular automata compatible with quantum mechanics?

    E-Print Network [OSTI]

    Hans-Thomas Elze

    2015-05-14

    We consider discrete and integer-valued cellular automata (CA). A particular class of which comprises "Hamiltonian CA" with equations of motion that bear similarities to Hamilton's equations, while they present discrete updating rules. The dynamics is linear, quite similar to unitary evolution described by the Schroedinger equation. This has been essential in our construction of an invertible map between such CA and continuous quantum mechanical models, which incorporate a fundamental discreteness scale. Based on Shannon's sampling theory, it leads, for example, to a one-to-one relation between quantum mechanical and CA conservation laws. The important issue of linearity of the theory is examined here by incorporating higher-order nonlinearities into the underlying action. These produce inconsistent nonlocal (in time) effects when trying to describe continuously such nonlinear CA. Therefore, in the present framework, only linear CA and local quantum mechanical dynamics are compatible.

  19. Cellular resolutions of noncommutative toric algebras from superpotentials

    E-Print Network [OSTI]

    Alastair Craw; Alexander Quintero Velez

    2011-12-14

    This paper constructs cellular resolutions for classes of noncommutative algebras, analogous to those introduced by Bayer-Sturmfels in the commutative case. To achieve this we generalise the dimer model construction of noncommutative crepant resolutions of toric algebras in dimension three by associating a superpotential and a notion of consistency to toric algebras of arbitrary dimension. For consistent algebras $A$, the coherent component of the fine moduli space of $A$-modules is constructed explicitly by GIT and provides a partial resolution of $\\Spec Z(A)$. For abelian skew group algebras and algebraically consistent dimer model algebras, we introduce a cell complex $\\Delta$ in a real torus whose cells describe uniformly all maps in the minimal projective bimodule resolution of $A$. We illustrate the general construction of $\\Delta$ for an example in dimension four arising from a tilting bundle on a smooth toric Fano threefold to highlight the importance of the incidence function on $\\Delta$.

  20. CANCELLED EMT and back again: does cellular plasticity fuelneoplasticprogressi on?

    SciTech Connect (OSTI)

    Turley, Eva A.; Veiseh, Mandana; Radisky, Derek C.; Bissell, MinaJ.

    2007-02-24

    Epithelial-mesenchymal transition (EMT) is a cellular transdifferentiation program that facilitates organ morphogenesis and tissue remodeling in physiological processes such as embryonic development and wound healing. However, a similar phenotypic conversion is also detected in fibrotic diseases and neoplasia, in which it is associated with disease progression. EMT in cancer epithelial cells often appears to be an incomplete and bi-directional process. Here we discuss the phenomenon of EMT as it pertains to tumor development, focusing on exceptions to the commonly held rule that EMT promotes invasion and metastasis. We also highlight the role of the Ras-controlled signaling mediators, ERK1, ERK2 and PI3-kinase, as microenvironmental responsive regulators of EMT.

  1. Dirac Quantum Cellular Automaton from Split-step Quantum Walk

    E-Print Network [OSTI]

    Arindam Mallick; C. M. Chandrashekar

    2015-09-29

    Simulations of one quantum system by an other has an implications in realization of quantum machine that can imitate any quantum systems and solve problems that are not accessible to classical computers. One of the approach to engineer quantum simulations is to discretize the space-time degree of freedom in quantum dynamics and define the quantum cellular automata (QCA), a local unitary update rule on a lattice. Different models of QCA are constructed using different set of conditions which are not uniquely defined. The form of the operators in these model are not always in implementable configuration on an other system. Here, starting from a split-step discrete-time quantum walk (DTQW) which are uniquely defined for experimental implementation, we recover the Dirac quantum cellular automaton (DQCA). This will bridge the connection between Dirac equation(DE)-DQCA-DTQW and eliminate the explicit use of invariance, symmetries and limiting range of parameter to establish the connections. For a combination of parameters defining the split-step DTQW, we will show the recovery of all the fine oscillation of the probability distribution in position observed in DQCA but not in conventional DTQW. We will also present the Zitterbewegung oscillations and quantify the entanglement as a function of that parameters that define split-step DTQW. The unique definition of DTQW along with the parameter tuneability demonstrated in experimental implementation will establish it as an efficient tool to design quantum simulator with access to different physical regime and approach quantum field theory from principles of quantum information theory.

  2. Recipes and mechanisms of cellular reprogramming: a case study on budding yeast Saccharomyces cerevisiae

    E-Print Network [OSTI]

    Ding, Shengchao; Wang, Wei

    2011-01-01

    as: Ding and Wang: Recipes and mechanisms of cellularARTICLE Open Access Recipes and mechanisms of cellularkey challenge is to find the recipes of perturbing genes to

  3. iPad Price Guide -2015 Wi-Fi Only Wi-Fi/Cellular

    E-Print Network [OSTI]

    Burton, Geoffrey R.

    iPad Price Guide - 2015 Wi-Fi Only Wi-Fi/Cellular 16GB 64GB 128GB Wi-Fi Only Wi-Fi/Cellular 16GB 64, 5MP iSight Camera Available in Space Grey or Silver Capacity Wi-Fi Only ÂŁ250 ex VAT ÂŁ281 ex VAT Wi-Fi/Cellular in Space Grey or Silver Capacity Wi-Fi Only ÂŁ187 ex VAT ÂŁ219 ex VAT Wi-Fi/Cellular ÂŁ266 ex VAT ÂŁ297 ex VAT

  4. Fault Locating, Prediction and Protection (FLPPS)

    SciTech Connect (OSTI)

    Yinger, Robert, J.; Venkata, S., S.; Centeno, Virgilio

    2010-09-30

    One of the main objectives of this DOE-sponsored project was to reduce customer outage time. Fault location, prediction, and protection are the most important aspects of fault management for the reduction of outage time. In the past most of the research and development on power system faults in these areas has focused on transmission systems, and it is not until recently with deregulation and competition that research on power system faults has begun to focus on the unique aspects of distribution systems. This project was planned with three Phases, approximately one year per phase. The first phase of the project involved an assessment of the state-of-the-art in fault location, prediction, and detection as well as the design, lab testing, and field installation of the advanced protection system on the SCE Circuit of the Future located north of San Bernardino, CA. The new feeder automation scheme, with vacuum fault interrupters, will limit the number of customers affected by the fault. Depending on the fault location, the substation breaker might not even trip. Through the use of fast communications (fiber) the fault locations can be determined and the proper fault interrupting switches opened automatically. With knowledge of circuit loadings at the time of the fault, ties to other circuits can be closed automatically to restore all customers except the faulted section. This new automation scheme limits outage time and increases reliability for customers. The second phase of the project involved the selection, modeling, testing and installation of a fault current limiter on the Circuit of the Future. While this project did not pay for the installation and testing of the fault current limiter, it did perform the evaluation of the fault current limiter and its impacts on the protection system of the Circuit of the Future. After investigation of several fault current limiters, the Zenergy superconducting, saturable core fault current limiter was selected for installation. Because of some testing problems with the Zenergy fault current limiter, installation was delayed until early 2009 with it being put into operation on March 6, 2009. A malfunction of the FCL controller caused the DC power supply to the superconducting magnet to be turned off. This inserted the FCL impedance into the circuit while it was in normal operation causing a voltage resonance condition. While these voltages never reached a point where damage would occur on customer equipment, steps were taken to insure this would not happen again. The FCL was reenergized with load on December 18, 2009. A fault was experienced on the circuit with the FCL in operation on January 14, 2010. The FCL operated properly and reduced the fault current by about 8%, what was expected from tests and modeling. As of the end of the project, the FCL was still in operation on the circuit. The third phase of the project involved the exploration of several advanced protection ideas that might be at a state where they could be applied to the Circuit of the Future and elsewhere in the SCE electrical system. Based on the work done as part of the literature review and survey, as well as a number of internal meetings with engineering staff at SCE, a number of ideas were compiled. These ideas were then evaluated for applicability and ability to be applied on the Circuit of the Future in the time remaining for the project. Some of these basic ideas were implemented on the circuit including measurement of power quality before and after the FCL. It was also decided that we would take what was learned as part of the Circuit of the Future work and extend it to the next generation circuit protection for SCE. Also at this time, SCE put in a proposal to the DOE for the Irvine Smart Grid Demonstration using ARRA funding. SCE was successful in obtaining funding for this proposal, so it was felt that exploration of new protection schemes for this Irvine Smart Grid Demonstration would be a good use of the project resources. With this in mind, a protection system that uses fault interrupting switches, hi

  5. The CD36, CLA-1(CD36L1), and LIMPII (CD36L2) gene family: Cellular distribution, chromosomal location, and genetic evolution

    SciTech Connect (OSTI)

    Calvo, D.; Vega, M.A.; Dopazo, J.

    1995-01-01

    CD36, CLA-1, and LIMPII are single polypeptide membrane glycoproteins, and the genes encoding them constitute a recently described gene family. In the present paper, a cDNA encoding the human lysosomal membrane protein LIMPII was used to determine its expression pattern in cells of various lineages. Like CLA-1, and in contrast with the restricted expression of CD36, the expression of LIMPII is widespread. Mapping of the human LIMPII and CLA-1 genes (gene symbols CD36L2 and CD36L1, respectively) to specific chromosomes revealed that CLA-1, LIMPII, and CD36 do not form a gene cluster, but are found dispersed on chromosomes 12, 4, and 7, respectively. These data, together with the phylogenetic analysis carried out for the members of this family, indicate that the LIMPII, CIA-1, and CD36 genes diverged early in evolution from an ancestor gene, possibly before the divergence between the arthropods and the vertebrates. 48 refs., 5 figs.

  6. Homodyne impulse radar hidden object locator

    DOE Patents [OSTI]

    McEwan, T.E.

    1996-04-30

    An electromagnetic detector is designed to locate an object hidden behind a separator or a cavity within a solid object. The detector includes a PRF generator for generating 2 MHz pulses, a homodyne oscillator for generating a 2 kHz square wave, and for modulating the pulses from the PRF generator. A transmit antenna transmits the modulated pulses through the separator, and a receive antenna receives the signals reflected off the object. The receiver path of the detector includes a sample and hold circuit, an AC coupled amplifier which filters out DC bias level shifts in the sample and hold circuit, and a rectifier circuit connected to the homodyne oscillator and to the AC coupled amplifier, for synchronously rectifying the modulated pulses transmitted over the transmit antenna. The homodyne oscillator modulates the signal from the PRF generator with a continuous wave (CW) signal, and the AC coupled amplifier operates with a passband centered on that CW signal. The present detector can be used in several applications, including the detection of metallic and non-metallic objects, such as pipes, studs, joists, nails, rebars, conduits and electrical wiring, behind wood wall, ceiling, plywood, particle board, dense hardwood, masonry and cement structure. The detector is portable, light weight, simple to use, inexpensive, and has a low power emission which facilitates the compliance with Part 15 of the FCC rules. 15 figs.

  7. Homodyne impulse radar hidden object locator

    DOE Patents [OSTI]

    McEwan, Thomas E. (Livermore, CA)

    1996-01-01

    An electromagnetic detector is designed to locate an object hidden behind a separator or a cavity within a solid object. The detector includes a PRF generator for generating 2 MHz pulses, a homodyne oscillator for generating a 2 kHz square wave, and for modulating the pulses from the PRF generator. A transmit antenna transmits the modulated pulses through the separator, and a receive antenna receives the signals reflected off the object. The receiver path of the detector includes a sample and hold circuit, an AC coupled amplifier which filters out DC bias level shifts in the sample and hold circuit, and a rectifier circuit connected to the homodyne oscillator and to the AC coupled amplifier, for synchronously rectifying the modulated pulses transmitted over the transmit antenna. The homodyne oscillator modulates the signal from the PRF generator with a continuous wave (CW) signal, and the AC coupled amplifier operates with a passband centered on that CW signal. The present detector can be used in several applications, including the detection of metallic and non-metallic objects, such as pipes, studs, joists, nails, rebars, conduits and electrical wiring, behind wood wall, ceiling, plywood, particle board, dense hardwood, masonry and cement structure. The detector is portable, light weight, simple to use, inexpensive, and has a low power emission which facilitates the compliance with Part 15 of the FCC rules.

  8. TAGGING, TRACKING AND LOCATING WITHOUT GPS

    SciTech Connect (OSTI)

    Cordaro, J.; Coleman, T.; Shull, D.

    2012-07-08

    The Savannah River National Laboratory (SRNL) was requested to lead a Law Enforcement Working Group that was formed to collaborate on common operational needs. All agencies represented on the working group ranked their need to tag, track, and locate a witting or unwitting target as their highest priority. Specifically, they were looking for technologies more robust than Global Positioning Satellite (GPS), could communicate back to the owner, and worked where normal cell phone communications did not work or were unreliable. SRNL brought together multiple technologies in a demonstration that was held in in various Alaska venues, including metropolitan, wilderness, and at-sea that met the working group's requirements. Using prototypical technologies from Boeing, On Ramp, and Fortress, SRNL was able to demonstrate the ability to track personnel and material in all scenarios including indoors, in heavily wooden areas, canyons, and in parking garages. In all cases GPS signals were too weak to measure. Bi-directional communication was achieved in areas that Wi-Fi, cell towers, or traditional radios would not perform. The results of the exercise will be presented. These technologies are considered ideal for tracking high value material such has nuclear material with a platform that allows seamless tracking anywhere in the world, indoors or outdoors.

  9. SAPLE: Sandia Advanced Personnel Locator Engine.

    SciTech Connect (OSTI)

    Procopio, Michael J.

    2010-04-01

    We present the Sandia Advanced Personnel Locator Engine (SAPLE) web application, a directory search application for use by Sandia National Laboratories personnel. SAPLE's purpose is to return Sandia personnel 'results' as a function of user search queries, with its mission to make it easier and faster to find people at Sandia. To accomplish this, SAPLE breaks from more traditional directory application approaches by aiming to return the correct set of results while placing minimal constraints on the user's query. Two key features form the core of SAPLE: advanced search query interpretation and inexact string matching. SAPLE's query interpretation permits the user to perform compound queries when typing into a single search field; where able, SAPLE infers the type of field that the user intends to search on based on the value of the search term. SAPLE's inexact string matching feature yields a high-quality ranking of personnel search results even when there are no exact matches to the user's query. This paper explores these two key features, describing in detail the architecture and operation of SAPLE. Finally, an extensive analysis on logged search query data taken from an 11-week sample period is presented.

  10. A unified Bayesian framework for relative microseismic location

    E-Print Network [OSTI]

    Poliannikov, Oleg V.

    We study the problem of determining an unknown microseismic event location relative to previously located events using a single monitoring array in a monitoring well. We show that using the available information about the ...

  11. Locations of Smart Grid Demonstration and Large-Scale Energy...

    Office of Environmental Management (EM)

    Locations of Smart Grid Demonstration and Large-Scale Energy Storage Projects Locations of Smart Grid Demonstration and Large-Scale Energy Storage Projects Map of the United States...

  12. A unified Bayesian framework for relative microseismic location

    E-Print Network [OSTI]

    Poliannikov, Oleg V.

    2013-01-01

    We study the problem of determining an unknown microseismic event location relative to previously located events using a single monitoring array in a monitoring well. We show that using the available information about the ...

  13. The Cricket Indoor Location System Nissanka Bodhi Priyantha

    E-Print Network [OSTI]

    applications. Cricket consists of location beacons that are attached to the ceiling of a building to compute their own locations. This active-beacon passive-listener architecture is scalable with respect

  14. Fire Alarm Control Panel is located in Switchgear

    E-Print Network [OSTI]

    KEY: NORTH CHDD-South Floor 1 Fire Alarm Control Panel is located in Switchgear Room #CD11A Panel is located in Switchgear Room #CD11A on Basement Level Evacuation Route Exit Restroom Fire

  15. Policy-aware sender anonymity in Location-based services

    E-Print Network [OSTI]

    Vyas, Avinash

    2011-01-01

    LBS Server Location Server CSP Sender Figure 1.1: LBS ModelService Provider, denoted as CSP, the Location Server,is either the MPC in the CSP’s network or an Over-The-Top (

  16. The ear as a location for wearable vital signs monitoring

    E-Print Network [OSTI]

    He, David Da

    Obtaining vital signs non-invasively and in a wearable manner is essential for personal health monitoring. We propose the site behind the ear as a location for an integrated wearable vital signs monitor. This location is ...

  17. A Look at Health Care Buildings - Where are they located

    U.S. Energy Information Administration (EIA) Indexed Site

    Location Return to: A Look at Health Care Buildings How large are they? How many employees are there? Where are they located? How old are they? Who owns and occupies them? Are they...

  18. Dynamic resource location in peer-to-peer networks 

    E-Print Network [OSTI]

    Nathuji, Ripal Babubhai

    2004-09-30

    Resource location is a necessary operation for computer applications. In large scale peer-to-peer systems, random search is a scalable approach for locating dynamic resources. Current peer-to-peer systems can be partitioned into those which rely...

  19. Magnetic pulsing technique for tracking, locating pigs. [Locating pipeline servicing equipment using magnetic pulsing

    SciTech Connect (OSTI)

    Farque, J.A. (C.D.I., Broken Arrow, OK (United States))

    1994-01-01

    Magnetic transmission systems work well in conjunction with pipe line pigging. They have transmission characteristics that allow an operator to track a pig as it moves through the line with one antenna orientation, and locate a stationary pig and transmitter to within inches with another. Advanced systems offer pig run documentation features by recording the images of transmitter passages and their times and dates. These features will become increasingly important to pipe line owners and operators in the future as the EPA tightens its grip on the pipe line and gas industries. Additionally, pigging personnel with no real experience with the tracking or location of pigs can operate a magnetic system and be immediately productive. This lowers the overall cost to the service company, the pipe line owner, and ultimately the end user of the product.

  20. TOPICS IN PROBABILISTIC LOCATION ESTIMATION IN WIRELESS NETWORKS

    E-Print Network [OSTI]

    Myllymäki, Petri

    TOPICS IN PROBABILISTIC LOCATION ESTIMATION IN WIRELESS NETWORKS Petri Kontkanen, Petri Myllym;TOPICS IN PROBABILISTIC LOCATION ESTIMATION IN WIRELESS NETWORKS Petri Kontkanen, Petri Myllym¨aki, Teemu, Spain, IEEE Press, 2004. TOPICS IN PROBABILISTIC LOCATION ESTIMATION IN WIRELESS NETWORKS Petri

  1. COMBINING LOCATION AND EXPRESSION DATA FOR PRINCIPLED DISCOVERY OF

    E-Print Network [OSTI]

    Hartemink, Alexander

    location data to guide the model induction process. We combine these two data modalities by al- lowing combine genomic location and expression data to guide the model induction process by permitting the formerCOMBINING LOCATION AND EXPRESSION DATA FOR PRINCIPLED DISCOVERY OF GENETIC REGULATORY NETWORK

  2. Risks of using AP locations discovered through war driving

    E-Print Network [OSTI]

    Kotz, David

    Risks of using AP locations discovered through war driving Minkyong Kim, Jeffrey J. Fielding the actual locations are often unavailable, they use estimated locations from war driving estimated through war driving. War driving is the process of collecting Wi-Fi beacons by driving or walking

  3. Location-based Sponsored Search Advertising George Trimponias1

    E-Print Network [OSTI]

    Papadias, Dimitris

    Location-based Sponsored Search Advertising George Trimponias1 , Ilaria Bartolini2 , Dimitris unprecedented opportunities for location-based advertising. In this work, we provide models and investigate the market for location-based sponsored search, where advertisers pay the search engine to be displayed

  4. Static and Dynamic Location Management in Distributed Mobile Environments

    E-Print Network [OSTI]

    Vaidya, Nitin

    Static and Dynamic Location Management in Distributed Mobile Environments P. Krishna y N. H. Vaidya for search, update and search-update. Static location management uses one combination of search, update the performance of di erent static location management strategies for various communicationand mobilitypatterns

  5. Telephone Service | Argonne National Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorking With U.S. CoalMexicoConference Tight Oil ProductionTitanX

  6. Fabrication of Functionally Graded-cellular Structures of Cement-based Materials by Co-

    E-Print Network [OSTI]

    Paulino, Glaucio H.

    Fabrication of Functionally Graded-cellular Structures of Cement-based Materials by Co- extrusion Y-extrusion of layered cement-based materials. The paste flow in the barrel and the die land in a ram extruder should. The functionally graded cellular structures of cement-based materials were successfully fabricated by co

  7. Impact of Topology and Shadowing on the Outage Probability of Cellular Networks

    E-Print Network [OSTI]

    Coupechoux, Marceau

    Impact of Topology and Shadowing on the Outage Probability of Cellular Networks Jean-Marc Kelif--This paper proposes an analytical study of the shadowing impact on the outage probability in cellular radio in the outage probability. From f, we are able to derive the outage probability of a mobile station (MS

  8. On the Impact of Mobility on Outage Probability in Cellular Networks

    E-Print Network [OSTI]

    Coupechoux, Marceau

    On the Impact of Mobility on Outage Probability in Cellular Networks Jean-Marc Kelif France Telecom an analytical study of the mobility in cellular networks and its impact on quality of service and outage power. It allows us to analyze users mobility and to derive expressions of the outage probability. We

  9. The study of solar flares with the extended cellular automaton (XCA) model

    E-Print Network [OSTI]

    Anastasiadis, Anastasios

    ) at a temporal snap­shot during a flare. explain the power­law frequency distributions of the solar flareThe study of solar flares with the extended cellular automaton (X­CA) model H. Isliker 1 , A of cellular automaton (CA) model, the extended CA (X­CA), for the study of solar flares. The X­CA model

  10. Exploiting Hidden Convexity For Flexible And Robust Resource Allocation In Cellular Networks

    E-Print Network [OSTI]

    Tan, Chee Wei

    transmission in a CDMA cellular network, we propose an optimal power control scheme with congestionExploiting Hidden Convexity For Flexible And Robust Resource Allocation In Cellular Networks Chee of the SIR-balancing power algorithm is optimized. I. INTRODUCTION A. Motivation Data transmission

  11. Random Linear Cellular Automata: Fractals associated with random multiplication of polynomials

    E-Print Network [OSTI]

    Mauldin, R. Daniel

    cellular automaton (LCA). As in the case of LCA with states in a nite eld we associate with this sequence with respect to linear cellular automata (LCA) with states in the residue classes of the integers modulo-similarity properties of the evolution patterns of the LCA. The self-similarity structure of the evolution set of LCA

  12. First Impressions on the State of Cellular Data Connectivity in India

    E-Print Network [OSTI]

    Ribeiro, Vinay

    First Impressions on the State of Cellular Data Connectivity in India Zahir Koradia Goutham Mannava Triukose Dept. of Comp Sc IIT Bombay Mumbai, India Dept. of Comp Sc IIT Delhi§ New Delhi, India National ICT Australia Sydney, Australia ABSTRACT Cellular penetration in India has grown tremendously in re

  13. Impact of Spatio-Temporal Power Sharing Policies on Cellular Network Greening

    E-Print Network [OSTI]

    Yi, Yung

    Impact of Spatio-Temporal Power Sharing Policies on Cellular Network Greening Jeongho Kwak, Kyuho in IM schemes on cellular network greening, where different spatio-temporal power sharing policies with greening, from which we first develop four IM schemes with different power sharing policies. Through

  14. Linking molecular affinity and cellular specificity in cadherin-mediated adhesion

    E-Print Network [OSTI]

    Ben-Shaul, Avinoam

    Linking molecular affinity and cellular specificity in cadherin-mediated adhesion P. Katsambaa,b,1 Kingdom Contributed by Barry H. Honig, May 15, 2009 (sent for review May 4, 2009) Many cell­cell adhesive is poorly understood, in part because the relationship between cellular adhesive specificity and intermolec

  15. Cellular Computing and Least Squares for partial differential problems parallel solving

    E-Print Network [OSTI]

    Nicolas Fressengeas; Hervé Frezza-Buet

    2010-01-29

    This paper shows how partial differential problems can be solved thanks to cellular computing and an adaptation of the Least Squares Finite Elements Method. As cellular computing can be implemented on distributed parallel architectures, this method allows the distribution of a resource demanding differential problem over a computer network.

  16. Mechanistic links between cellular trade-offs, gene expression, and growth

    E-Print Network [OSTI]

    Swain, Peter

    Mechanistic links between cellular trade-offs, gene expression, and growth Andrea Y. Weißea, are not well understood. Here we consider three trade-offs that, because of limitations in levels of cellular energy, free ribosomes, and proteins, are faced by all living cells and we construct a mechanistic model

  17. A Mobility Model for Cost Analysis in Integrated Cellular/WLANs

    E-Print Network [OSTI]

    Shenoy, Nirmala

    A Mobility Model for Cost Analysis in Integrated Cellular/WLANs Nirmala Shenoy, Bruce Hartpence, Information Technology Department, Rochester Institute of Technology, Rochester NY 14623, USA Rafael Mantilla that can be used to study the costs and benefits of integrating cellular and Wireless LANs, from a vendor

  18. Radiation damage in the LHCb Vertex Locator

    E-Print Network [OSTI]

    A. Affolder; K. Akiba; M. Alexander; S. Ali; M. Artuso; J. Benton; M. van Beuzekom; P. M. Bj\\ornstad; G. Bogdanova; S. Borghi; T. J. V. Bowcock; H. Brown; J. Buytaert; G. Casse; P. Collins; S. De Capua; D. Dossett; L. Eklund; C. Farinelli; J. Garofoli; M. Gersabeck; T. Gershon; H. Gordon; J. Harrison; V. Heijne; K. Hennessy; D. Hutchcroft; E. Jans; M. John; T. Ketel; G. Lafferty; T. Latham; A. Leflat; M. Liles; D. Moran; I. Mous; A. Oblakowska-Mucha; C. Parkes; G. D. Patel; S. Redford; M. M. Reid; K. Rinnert; E. Rodrigues; M. Schiller; T. Szumlak; C. Thomas; J. Velthuis; V. Volkov; A. D. Webber; M. Whitehead; E. Zverev

    2013-02-21

    The LHCb Vertex Locator (VELO) is a silicon strip detector designed to reconstruct charged particle trajectories and vertices produced at the LHCb interaction region. During the first two years of data collection, the 84 VELO sensors have been exposed to a range of fluences up to a maximum value of approximately $\\rm{45 \\times 10^{12}\\,1\\,MeV}$ neutron equivalent ($\\rm{1\\,MeV\\,n_{eq}}$). At the operational sensor temperature of approximately $-7\\,^{\\circ}\\rm{C}$, the average rate of sensor current increase is $18\\,\\upmu\\rm{A}$ per $\\rm{fb^{-1}}$, in excellent agreement with predictions. The silicon effective bandgap has been determined using current versus temperature scan data after irradiation, with an average value of $E_{g}=1.16\\pm0.03\\pm0.04\\,\\rm{eV}$ obtained. The first observation of n-on-n sensor type inversion at the LHC has been made, occurring at a fluence of around $15 \\times 10 ^{12}$ of $1\\,\\rm{MeV\\,n_{eq}}$. The only n-on-p sensors in use at the LHC have also been studied. With an initial fluence of approximately $\\rm{3 \\times 10^{12}\\,1\\,MeV\\,n_{eq}}$, a decrease in the Effective Depletion Voltage (EDV) of around 25\\,V is observed, attributed to oxygen induced removal of boron interstitial sites. Following this initial decrease, the EDV increases at a comparable rate to the type inverted n-on-n type sensors, with rates of $(1.43\\pm 0.16) \\times 10 ^{-12}\\,\\rm{V} / \\, 1 \\, \\rm{MeV\\,n_{eq}}$ and $(1.35\\pm 0.25) \\times 10 ^{-12}\\,\\rm{V} / \\, 1 \\, \\rm{MeV\\,n_{eq}}$ measured for n-on-p and n-on-n type sensors, respectively. A reduction in the charge collection efficiency due to an unexpected effect involving the second metal layer readout lines is observed.

  19. Cellular Networks as Models for Planck-Scale Physics

    E-Print Network [OSTI]

    Manfred Requardt

    1998-06-17

    Starting from the working hypothesis that both physics and the corresponding mathematics have to be described by means of discrete concepts on the Planck scale, one of the many problems one has to face in this enterprise is to find the discrete protoforms of the building blocks of our ordinary continuum physics and mathematics. We base our own approach on what we call `cellular networks', consisting of cells (nodes) interacting with each other via bonds (figuring as elementary interactions) according to a certain `local law'. Geometrically our dynamical networks are living on graphs. Hence a substantial amount of the investigation is devoted to the developement of various versions of discrete (functional) analysis and geometry on such (almost random) webs. Another important topic we address is a suitable concept of intrinsic (fractal) dimension on erratic structures of this kind. In the course of the investigation we make comments concerning both different and related approaches to quantum gravity as, say, the spin network framework. It may perhaps be said that certain parts of our programme seem to be a realisation of ideas sketched by Smolin some time ago (see the introduction).

  20. Asymptotic properties of the Dirac quantum cellular automaton

    E-Print Network [OSTI]

    A. Pérez

    2015-04-28

    We show that the Dirac quantum cellular automaton [Ann. Phys. 354 (2015) 244] shares many properties in common with the discrete-time quantum walk. These similarities can be exploited to redefine the automaton as a unitary process that takes place at regular time steps on a one-dimensional lattice with an arbitrary lattice spacing. In this way, it becomes an alternative to the quantum walk, with a dispersion relation that can be controlled by a mass parameter, playing a similar role to the coin angle in the quantum walk. Moreover, the Dirac Hamiltonian is recovered under a suitable limit. We also provide two independent analytical approximations to the long term probability distribution. It is shown that, starting from localized conditions, the asymptotic value of the entropy of entanglement between internal and motional degrees of freedom overcomes the known limit that is approached by the quantum walk for the same initial conditions, and are similar to the ones achieved by highly localized states of the Dirac equation.

  1. 110. Location efficiency Discovering the hidden transportation costs of where you live page 1 / 1 110. Location efficiency

    E-Print Network [OSTI]

    Machel, Hans

    110. Location efficiency Discovering the hidden transportation costs of where you live page 1 / 1 110. Location efficiency: Discovering the hidden transportation costs of where you live Live location efficiency and it's the amount of time, energy and greenhouse gas emissions you spend getting

  2. IGF-I enhances cellular senescence via the reactive oxygen species-p53 pathway

    SciTech Connect (OSTI)

    Handayaningsih, Anastasia-Evi; Takahashi, Michiko; Fukuoka, Hidenori; Iguchi, Genzo; Nishizawa, Hitoshi; Yamamoto, Masaaki; Suda, Kentaro; Takahashi, Yutaka

    2012-08-24

    Highlights: Black-Right-Pointing-Pointer Cellular senescence plays an important role in tumorigenesis and aging process. Black-Right-Pointing-Pointer We demonstrated IGF-I enhanced cellular senescence in primary confluent cells. Black-Right-Pointing-Pointer IGF-I enhanced cellular senescence in the ROS and p53-dependent manner. Black-Right-Pointing-Pointer These results may explain the underlying mechanisms of IGF-I involvement in tumorigenesis and in regulation of aging. -- Abstract: Cellular senescence is characterized by growth arrest, enlarged and flattened cell morphology, the expression of senescence-associated {beta}-galactosidase (SA-{beta}-gal), and by activation of tumor suppressor networks. Insulin-like growth factor-I (IGF-I) plays a critical role in cellular growth, proliferation, tumorigenesis, and regulation of aging. In the present study, we show that IGF-I enhances cellular senescence in mouse, rat, and human primary cells in the confluent state. IGF-I induced expression of a DNA damage marker, {gamma}H2AX, the increased levels of p53 and p21 proteins, and activated SA-{beta}-gal. In the confluent state, an altered downstream signaling of IGF-I receptor was observed. Treatment with a reactive oxygen species (ROS) scavenger, N-acetylcystein (NAC) significantly suppressed induction of these markers, indicating that ROS are involved in the induction of cellular senescence by IGF-I. In p53-null mouse embryonic fibroblasts, the IGF-I-induced augmentation of SA-{beta}-gal and p21 was inhibited, demonstrating that p53 is required for cellular senescence induced by IGF-I. Thus, these data reveal a novel pathway whereby IGF-I enhances cellular senescence in the ROS and p53-dependent manner and may explain the underlying mechanisms of IGF-I involvement in tumorigenesis and in regulation of aging.

  3. Automated detection and location of indications in eddy current signals

    DOE Patents [OSTI]

    Brudnoy, David M. (Albany, NY); Oppenlander, Jane E. (Burnt Hills, NY); Levy, Arthur J. (Schenectady, NY)

    2000-01-01

    A computer implemented information extraction process that locates and identifies eddy current signal features in digital point-ordered signals, signals representing data from inspection of test materials, by enhancing the signal features relative to signal noise, detecting features of the signals, verifying the location of the signal features that can be known in advance, and outputting information about the identity and location of all detected signal features.

  4. Does cellular aging relate to patterns of allostasis?. An examination of basal and stress reactive HPA axis activity and telomere length.

    E-Print Network [OSTI]

    2011-01-01

    A recipe for accelerated cellular aging? Hormones (Athens).physbeh.2011.11.016. Does cellular aging relate to patternsAllostatic load; Telomere; Cellular aging; Stress; HPA axis

  5. Cognitive Behavioral Therapy and Tai Chi Reverse Cellular and Genomic Markers of Inflammation in Late Life Insomnia: A Randomized Controlled Trial

    E-Print Network [OSTI]

    2015-01-01

    2008): Sleep loss activates cellular in?ammatory signaling.al. (2014): Tai Chi, cellular in?ammation, and transcriptomeTherapy and Tai Chi Reverse Cellular and Genomic Markers of

  6. Condensing Heating and Water Heating Equipment Workshop Location...

    Energy Savers [EERE]

    Condensing Heating and Water Heating Equipment Workshop Location: Washington Gas Light Appliance Training Facility 6801 Industrial Road Springfield, VA Date: October 9, 2014 Time:...

  7. Policy-aware sender anonymity in Location-based services

    E-Print Network [OSTI]

    Vyas, Avinash

    2011-01-01

    from attackers who (via hacking or subpoenas) gain access toagainst attackers who, via hacking or subpoenas, gain accessthe location database D 1 (via hacking or subpoena) and is “

  8. Located in historic Los Alamos, New Mexico against the backdrop...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Located in historic Los Alamos, New Mexico against the backdrop of the lush Jemez Mountains, Los Alamos National Laboratory (LANL) offers its education program participants...

  9. Attack-Resistant Location Estimation in Sensor (Revised August 2005)

    E-Print Network [OSTI]

    Ning, Peng

    role in many sensor network applications. Not only do applications such as environment monitoring and target tracking require sensors' location information to fulfill their tasks, but several fundamental

  10. Wind Turbine Manufacturers in the U. S.: Locations and Local...

    Wind Powering America (EERE)

    Efficiency and Renewable Energy, operated by the Alliance for Sustainable Energy, LLC. Wind Turbine Manufacturers in the U.S.: Locations and Local Impacts WINDPOWER 2010 Conference...

  11. Title 33 CFR 115 Bridge Locations and Clearances: Administrative...

    Open Energy Info (EERE)

    Title 33 CFR 115 Bridge Locations and Clearances: Administrative Procedures Jump to: navigation, search OpenEI Reference LibraryAdd to library Legal Document- Federal...

  12. Alternative Fueling Station Locator App Provides Info at Your...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    stations that offer electricity, natural gas, biodiesel, E85, propane, or hydrogen. | Energy Department The Alternative Fueling Station Locator iPhone app helps you find...

  13. Identification of High Collision Concentration Locations Under Wet Weather Conditions

    E-Print Network [OSTI]

    Hwang, Taesung; Chung, Koohong; Ragland, David; Chan, Chin-Yao

    2008-01-01

    conducted under wet weather conditions. Observations fromLeahy, M. , and Suggett, J. Weather as a Chronic Hazard forLocations Under Wet Weather Conditions Taesung Hwang,

  14. Microfabricated arrays for high-throughput screening of cellular response to cyclic substrate deformation

    E-Print Network [OSTI]

    Sun, Yu

    and pathobiology. Introduction The large number of factors in the cellular milieu that can impact biological to other stimuli, including matrix proteins,12 chemical cues,13 and genetic therapies.14 In some cases

  15. Compressive behavior of trabecular bone in the proximal tibia using a cellular solid model 

    E-Print Network [OSTI]

    Prommin, Danu

    2005-11-01

    In this study, trabecular architecture is considered as a cellular solid structure, including both intact and damaged bone models. ??Intact?? bone models were constructed based on ideal versions of 25, 60 and 80-year-old ...

  16. Detecting the Presence of a Proximate Cellular User through Distributed Femtocell Sensing 

    E-Print Network [OSTI]

    Parag, Pankaj 1988-

    2012-11-15

    to gain insight about proximate cellular devices. The proposed inference scheme leads to a significant performance gain over oblivious femtocells. Experimental results are provided to support this study and its conclusions....

  17. Design and application of a cellular, piezoelectric, artificial muscle actuator for biorobotic systems

    E-Print Network [OSTI]

    Secord, Thomas W. (Thomas William)

    2010-01-01

    One of the foremost challenges in robotics is the development of muscle-like actuators that have the capability to reproduce the smooth motions observed in animals. Biological muscles have a unique cellular structure that ...

  18. A constraint optimization framework for discovery of cellular signaling and regulatory networks

    E-Print Network [OSTI]

    Huang, Shao-shan Carol

    2011-01-01

    Cellular signaling and regulatory networks underlie fundamental biological processes such as growth, differentiation, and response to the environment. Although there are now various high-throughput methods for studying ...

  19. Design and analysis of active fluid-and-cellular solid composites for controllable stiffness robotic elements

    E-Print Network [OSTI]

    Cheng, Nadia G. (Nadia Gen San)

    2009-01-01

    The purpose of this thesis is to investigate the use of a new class of materials for realizing soft robots. Specifically, meso-scale composites--composed of cellular solids impregnated with active fluids-were be designed ...

  20. Stochastic Forecasts Achieve High Throughput and Low Delay over Cellular Networks

    E-Print Network [OSTI]

    Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory; Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science; Balakrishnan, Hari; Winstein, Keith J.; Sivaraman Kaushalram, Anirudh; Balakrishnan, Hari

    Sprout is an end-to-end transport protocol for interactive applications that desire high throughput and low delay. Sprout works well over cellular wireless networks, where link speeds change dramatically with time, and ...

  1. Cellular and genetic mechanisms of new tissue production in the regenerating planarian Schmidtea mediterranea

    E-Print Network [OSTI]

    Wagner, Daniel Elger

    2012-01-01

    Regeneration of missing body parts is biologically fascinating, yet poorly understood. Many instances of regeneration, such as the replacement of amphibian limbs or planarian heads, require both a source for new cellular ...

  2. Toward Real-time Modeling of Human Heart Ventricles at Cellular...

    Office of Scientific and Technical Information (OSTI)

    Conference: Toward Real-time Modeling of Human Heart Ventricles at Cellular Resolution: Multi-hour Simulation of Drug-induced Arrhythmias Citation Details In-Document Search Title:...

  3. Comprehensive functional testing and dynamic compensation techniques for Cellular Neural Networks 

    E-Print Network [OSTI]

    Grimaila, Michael Russell

    1995-01-01

    Cellular Neural Networks (CNN's) are analog, non-linear, dynamic systems which are especially well suited for solving problems in the areas of image processing and pattern recognition. State of the art implementations of ...

  4. Investigations of Game of Life cellular automata rules on Penrose Tilings: lifetime and ash

    E-Print Network [OSTI]

    Stepney, Susan

    Investigations of Game of Life cellular automata rules on Penrose Tilings: lifetime and ash; section 6 reports the statistics of lifetimes, ash densities, and growth of the region of activity. 2

  5. Mapping textures on 3d terrains: a hybrid cellular automata approach 

    E-Print Network [OSTI]

    Sinvhal, Swapnil

    2007-04-25

    It is a time consuming task to generate textures for large 3D terrain surfaces in computer games, flight simulations and computer animations. This work explores the use of cellular automata in the automatic generation of ...

  6. E. coliquantum dot bioconjugates as whole-cell fluorescent reporters for probing cellular damage

    E-Print Network [OSTI]

    Yanikoglu, Berrin

    . In this study, multi-walled carbon nanotubes (CNTs) were utilized as a model nanomaterial to probe cellular attraction16 and nickel- based histidine tagging.3 Covalent conjugation of QDs is the most commonly used

  7. Mechanical Signaling Induced Cellular Remodeling Studied By Integrated Optical And Atomic Force Microscopy 

    E-Print Network [OSTI]

    Sreenivasappa, Harini Bytaraya

    2014-12-08

    Vascular wall composition and mechanics are important for cardiovascular physiology and pathology. The reciprocal interaction between cells and their microenvironment influence cellular adaptation to external mechanical cues through the remodeling...

  8. Cellular resolution ex vivo imaging of gastrointestinal tissues with coherence microscopy

    E-Print Network [OSTI]

    Fujimoto, James G.

    Optical coherence microscopy (OCM) combines confocal microscopy and optical coherence tomography (OCT) to improve imaging depth and contrast, enabling cellular imaging in human tissues. We aim to investigate OCM for ex ...

  9. Cellular and axonal plasticity in the lesioned spinal cord of adult zebrafish 

    E-Print Network [OSTI]

    Kuscha, Veronika

    2011-11-25

    that signals released by descending axons are involved in cellular regeneration around the lesion site. Dopaminergic axons of supraspinal origin sprout rostral, but are almost completely absent caudal to the lesion site at two weeks post-lesion. Moreover, we...

  10. Cellular Barcodes for Efficiently Profiling Single-Cell Secretory Responses by Microengraving

    E-Print Network [OSTI]

    Yamanaka, Yvonne Joy

    We present a method that uses fluorescent cellular barcodes to increase the number of unique samples that can be analyzed simultaneously by microengraving, a nanowell array-based technique for quantifying the secretory ...

  11. Engineered sensors and genetic regulatory networks for control of cellular metabolism

    E-Print Network [OSTI]

    Moser, Felix, Ph. D. Massachusetts Institute of Technology

    2013-01-01

    Complex synthetic genetic programs promise unprecedented control over cellular metabolism and behavior. In this thesis, I describe the design and development of a synthetic genetic program to detect conditions underlying ...

  12. The Masterbuilder -June 2011 www.masterbuilder.co.in26 Cellular Geosynthetics: Geofoams

    E-Print Network [OSTI]

    Horvath, John S.

    cement), and - cellular glass. The polymeric category is further subdivided depending on the polymer; and - development of 'anti-buoyancy' EPS blocks that allow groundwater infiltration during times of flooding so

  13. 9.09J / 7.29J Cellular Neurobiology, Spring 2005

    E-Print Network [OSTI]

    Littleton, Troy

    This course serves as an introduction to the structure and function of the nervous system. Emphasis is placed on the cellular properties of neurons and other excitable cells. Topics covered include the structure and ...

  14. Coulter counter determination of bacterial growth and cellular size change following ??Co gamma irradiation 

    E-Print Network [OSTI]

    Gaston, Gary W

    1976-01-01

    COULTER COUNTER DETERMINATION OF BACTERIAL GROWTH AND CELLULAR SIZE CHANGE FOLLOWING Co GAMMA IRRADIATION A Thesis by GARY W. GASTON Submitted to the Graduate College of Texas A&M University in partial fulfillment of the requirement... for the degree of MASTER OF SCIENCE December 1976 Ma)or Subject: Biophysics COULTER COUNTER DETERMINATION OF BACTERIAL GROWTH AND CELLULAR SIZE CHANGE FOLLOWING Co GAMMA IRRADIATION A Thesis by GARY W. GASTON APPROVED as to style and content by: ead...

  15. A Location Management System for Destination Prediction from Smartphone Sensors

    E-Print Network [OSTI]

    Cho, Sung-Bae

    the current sensor values. The proposed system consists of five modules. Three modules perform to manage collection, the system generates new information. 2) Location extraction: It extacts location, which prediction method using linear regression, logistic regression and random forest [5]. It uses the information

  16. Models for Offender Target Location Selection with Explicit Dependency Structures

    E-Print Network [OSTI]

    O'Leary, Michael

    Models for Offender Target Location Selection with Explicit Dependency Structures Mike O'Leary April 30 - May 1, 2012 O'Leary & Tucker (Towson University) Target Location Selection QMDNS 2012 1 / 54 in this study We thank Phil Canter from the Baltimore County Police Department for his assistance. O'Leary

  17. A MODELING APPROACH FOR LOCATING LOGISTICS PLATFORMS FOR FAST PARCEL

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    1 29 A MODELING APPROACH FOR LOCATING LOGISTICS PLATFORMS FOR FAST PARCEL DELIVERY IN URBAN AREAS for optimizing, in a sustainable way (i.e. economical, eco-friendly and societal), the location of logistics has a logistics platform right in its centre (ARENC: 41362 m2 of warehouses and offices

  18. Facility Location with Hierarchical Facility Costs Zoya Svitkina #

    E-Print Network [OSTI]

    Tardos, Ă?va

    Facility Location with Hierarchical Facility Costs Zoya Svitkina # â?? Eva Tardos + Abstract We consider the facility location problem with hierarchi­ cal facility costs, and give a (4 installation costs. Shmoys, Swamy and Levi [13] gave an approxi­ mation algorithm for a two­level version

  19. Facility Location Under Uncertainty: A Review Lawrence V. Snyder

    E-Print Network [OSTI]

    Snyder, Larry

    for researchers in both the logistics and stochastic/robust optimization com- munities. Indeed, a large number in facility location are not available, we provide examples from the more general logistics literature. 1 Introduction Facility location decisions are costly and difficult to reverse, and their impact spans a long

  20. Location Update Accuracy in Human Tracking system using Zigbee modules

    E-Print Network [OSTI]

    Amutha, B

    2009-01-01

    A location and tracking system becomes very important to our future world of pervasive computing. An algorithm for accurate location information is being incorporated in the human walking model and in the blind human walking model. We want to implement an accurate location tracking mechanism using Zigbee along with GPS, we have incorporated Markov chain algorithm for establishing accuracy. Normal Human and blind human walking steps were actually taken in the known environment within our campus and the Markov chain algorithm was used for smoothening the stepwise variation in location updates. A comparison module is also implemented to show the difference between normal human and blind human walking step variations. This accuracy is used for designing a blind tracking device so that the device can be used by the blind for finding the path without obstacles. We present a system level approach to localizing and tracking Human and blind users on a basis of different sources of location information [GPS plus Zigbee...

  1. Math 577 Computational Mathematics I Time and Location: 1:50--3:05 TR, Location E1 242

    E-Print Network [OSTI]

    Fasshauer, Greg

    Math 577 ­ Computational Mathematics I Time and Location: 1:50--3:05 TR, Location E1 242 Instructor: Mathematics of Scientific Computing, 3rd Ed, Brooks/Cole (2002), ISBN 0-534-38905-8. Other required material numerical methods for computing eigenvalues and their derivation. 4. Students will understand the basic

  2. Cell-to-cell communication and cellular environment alter the somatostatin status of delta cells

    SciTech Connect (OSTI)

    Kelly, Catriona; Flatt, Peter R.; McClenaghan, Neville H.

    2010-08-20

    Research highlights: {yields} TGP52 cells display enhanced functionality in pseudoislet form. {yields} Somatostatin content was reduced, but secretion increased in high glucose conditions. {yields} Cellular interactions and environment alter the somatostatin status of TGP52 cells. -- Abstract: Introduction: Somatostatin, released from pancreatic delta cells, is a potent paracrine inhibitor of insulin and glucagon secretion. Islet cellular interactions and glucose homeostasis are essential to maintain normal patterns of insulin secretion. However, the importance of cell-to-cell communication and cellular environment in the regulation of somatostatin release remains unclear. Methods: This study employed the somatostatin-secreting TGP52 cell line maintained in DMEM:F12 (17.5 mM glucose) or DMEM (25 mM glucose) culture media. The effect of pseudoislet formation and culture medium on somatostatin content and release in response to a variety of stimuli was measured by somatostatin EIA. In addition, the effect of pseudoislet formation on cellular viability (MTT and LDH assays) and proliferation (BrdU ELISA) was determined. Results: TGP52 cells readily formed pseudoislets and showed enhanced functionality in three-dimensional form with increased E-cadherin expression irrespective of the culture environment used. However, culture in DMEM decreased cellular somatostatin content (P < 0.01) and increased somatostatin secretion in response to a variety of stimuli including arginine, calcium and PMA (P < 0.001) when compared with cells grown in DMEM:F12. Configuration of TGP52 cells as pseudoislets reduced the proliferative rate and increased cellular cytotoxicity irrespective of culture medium used. Conclusions: Somatostatin secretion is greatly facilitated by cell-to-cell interactions and E-cadherin expression. Cellular environment and extracellular glucose also significantly influence the function of delta cells.

  3. Anywhere But Here: An Introduction to State Control of Hazardous Waste Facility Location

    E-Print Network [OSTI]

    Tarlock, Dan A.

    1981-01-01

    State Control Of Hazardous- Waste Facility Location A. Danautonomy over the location of hazardous-waste managementa hazardous-waste facility-siting process is the location of

  4. An Information Theoretic Location Verification System for Wireless Networks

    E-Print Network [OSTI]

    Yan, Shihao; Nevat, Ido; Peters, Gareth W

    2012-01-01

    As location-based applications become ubiquitous in emerging wireless networks, Location Verification Systems (LVS) are of growing importance. In this paper we propose, for the first time, a rigorous information-theoretic framework for an LVS. The theoretical framework we develop illustrates how the threshold used in the detection of a spoofed location can be optimized in terms of the mutual information between the input and output data of the LVS. In order to verify the legitimacy of our analytical framework we have carried out detailed numerical simulations. Our simulations mimic the practical scenario where a system deployed using our framework must make a binary Yes/No "malicious decision" to each snapshot of the signal strength values obtained by base stations. The comparison between simulation and analysis shows excellent agreement. Our optimized LVS framework provides a defence against location spoofing attacks in emerging wireless networks such as those envisioned for Intelligent Transport Systems, wh...

  5. Healthcare Facility Location and Capacity Configuration under Stochastic Demand 

    E-Print Network [OSTI]

    Han, Xue

    2014-12-18

    This dissertation addresses two topics. The first topic is strategic dynamic supply chain reconfiguration (DSCR) problem, in which the proposed capacity configuration network is employed in the second topic: healthcare facility location and capacity...

  6. Location-based information system for open spaces 

    E-Print Network [OSTI]

    Tejavanija, Kampanart

    2004-11-15

    positioning system (GPS) in providing location information, it is expected that this technology could be utilized to control and improve building construction and facility management productivity within building interior spaces as well. However, GPS cannot...

  7. Object Co-location and Memory Reuse for Java Programs

    E-Print Network [OSTI]

    Lau, Francis C.M.

    : Memory allocator, garbage collector, mutator, Java, object co- location, memory reuse ACM Reference of a runtime system becomes increasingly signif- icant [Sun Microsystems 2003]. Our second goal is to find

  8. Network Based Approaches for Clustering and Location Decisions 

    E-Print Network [OSTI]

    Verma, Anurag

    2012-10-19

    , which is critical to the quality of service provided in a large scale emergency like an earthquake. In the existing literature, large scale emergency facility location models have either assumed that disaster response facilities will always...

  9. MARVEL: A System for Recognizing World Locations with Stereo Vision

    E-Print Network [OSTI]

    Braunegg, David Jerome

    1990-06-01

    To use a world model, a mobile robot must be able to determine its own position in the world. To support truly autonomous navigation, I present MARVEL, a system that builds and maintains its own models of world locations ...

  10. A Geographic Information Retrieval Approach to Locate Pharmacies on Duty

    E-Print Network [OSTI]

    Rosso, Paolo

    Geographic Information Retrieval (GIR), Geographic Information Systems (GIS), Toponym Disambiguation 1 disciplines, in particular geographic information retrieval and geographical information systems, which playedGIRPharma: A Geographic Information Retrieval Approach to Locate Pharmacies on Duty Francisco M

  11. Infill location determination and assessment of corresponding uncertainty 

    E-Print Network [OSTI]

    Senel, Ozgur

    2009-05-15

    , generated probabilistic distributions of incremental field production and, finally, used descriptive statistical analysis to evaluate results. I quantified the uncertainty associated with infill location selection in terms of incremental field production...

  12. Identifying Infill Locations and Underperformer Wells in Mature Fields using

    E-Print Network [OSTI]

    Mohaghegh, Shahab

    field. Identify opportunities in mature fields: Sweet spots for infill drilling. Underperformer wellsIdentifying Infill Locations and Underperformer Wells in Mature Fields using Monthly Production wells rather than the entire field. #12;Introduction Objective Methodology Results Conclusion Objective

  13. SOIL MICROBIOLOGY Resource Use of Soilborne Streptomyces Varies with Location,

    E-Print Network [OSTI]

    Thomas, David D.

    SOIL MICROBIOLOGY Resource Use of Soilborne Streptomyces Varies with Location, Phylogeny in prairie soils. Resource use patterns were highly variable among Streptomyces isolates and were soils less than 1 m apart differed significantly in their ability to use resources, indicating

  14. Colorado CRS 29-20-108, Location, Construction, or Improvement...

    Open Energy Info (EERE)

    Colorado CRS 29-20-108, Location, Construction, or Improvement of Major Electrical or Natural Gas Facilities Jump to: navigation, search OpenEI Reference LibraryAdd to library...

  15. Identification of critical locations across multiple infrastructures for terrorist actions

    E-Print Network [OSTI]

    Patterson, Sean A. (Sean Albert), 1981-

    2005-01-01

    This paper discusses a possible approach to ranking geographic regions that can influence multiple infrastructures. Once ranked, decision makers can determine whether these regions are critical locations based on their ...

  16. The Value of Flexibility in Robust Location-Transportation Problem

    E-Print Network [OSTI]

    2014-11-24

    Facility location decisions play a critical role in transportation planning. ... little is known about future demand, robust optimization, namely using a budgeted ... acterized by Dj. The total profit generated by the company is computed based on

  17. Short & long run transmission incentives for generation location

    E-Print Network [OSTI]

    Turvey, Ralph

    2006-01-01

    This paper is about one aspect of Britain's electricity trading system, its advantages and its weaknesses concerning the incentives it provides or fails to provide for the location of generation. (Similar considerations ...

  18. NMOCD - Form G-102 - Geothermal Resources Well Location and Acreage...

    Open Energy Info (EERE)

    NMOCD - Form G-102 - Geothermal Resources Well Location and Acreage Dedication Plat Jump to: navigation, search OpenEI Reference LibraryAdd to library General: NMOCD - Form G-102 -...

  19. Location of the solar dynamo and near-surface shear

    E-Print Network [OSTI]

    Axel Brandenburg

    2005-12-29

    The location of the solar dynamo is discussed in the context of new insights into the theory of nonlinear turbulent dynamos. It is argued that, from a dynamo-theoretic point of view, the bottom of the convection zone is not a likely location and that the solar dynamo may be distributed over the convection zone. The near surface shear layer produces not only east-west field alignment, but it also helps the dynamo disposing of its excess small scale magnetic helicity.

  20. Predicting threshold and location of laser damage on optical surfaces

    DOE Patents [OSTI]

    Siekhaus, Wigbert (Berkeley, CA)

    1987-01-01

    An apparatus useful in the prediction of the damage threshold of various optical devices, the location of weak spots on such devices and the location, identification, and elimination of optical surface impurities comprising, a focused and pulsed laser, an photo electric detector/imaging means, and a timer. The weak spots emit photoelectrons when subjected to laser intensities that are less than the intensity actually required to produce the damage. The weak spots may be eliminated by sustained exposure to the laser beam.

  1. A coarse-grained model for the simulations of biomolecular interactions in cellular environments

    SciTech Connect (OSTI)

    Xie, Zhong-Ru; Chen, Jiawen; Wu, Yinghao

    2014-02-07

    The interactions of bio-molecules constitute the key steps of cellular functions. However, in vivo binding properties differ significantly from their in vitro measurements due to the heterogeneity of cellular environments. Here we introduce a coarse-grained model based on rigid-body representation to study how factors such as cellular crowding and membrane confinement affect molecular binding. The macroscopic parameters such as the equilibrium constant and the kinetic rate constant are calibrated by adjusting the microscopic coefficients used in the numerical simulations. By changing these model parameters that are experimentally approachable, we are able to study the kinetic and thermodynamic properties of molecular binding, as well as the effects caused by specific cellular environments. We investigate the volumetric effects of crowded intracellular space on bio-molecular diffusion and diffusion-limited reactions. Furthermore, the binding constants of membrane proteins are currently difficult to measure. We provide quantitative estimations about how the binding of membrane proteins deviates from soluble proteins under different degrees of membrane confinements. The simulation results provide biological insights to the functions of membrane receptors on cell surfaces. Overall, our studies establish a connection between the details of molecular interactions and the heterogeneity of cellular environments.

  2. Application of Location/Allocation Models and GIS to the Location of National Primary Schools in Rawang, Malaysia 

    E-Print Network [OSTI]

    Naharudin, Nabilah

    2014-11-30

    As education is compulsory in Malaysia, all children aged 7 to 12 are expected to attend primary schools. It is therefore a challenge for the government to provide schools which are well located to serve the children ...

  3. 2012 CELLULAR & MOLECULAR FUNGAL BIOLOGY GORDON RESEARCH CONFERENCE, JUNE 17 - 22, 2012

    SciTech Connect (OSTI)

    Judith Berman

    2012-06-22

    The Gordon Research Conference on CELLULAR & MOLECULAR FUNGAL BIOLOGY was held at Holderness School, Holderness New Hampshire, June 17 - 22, 2012. The 2012 Gordon Conference on Cellular and Molecular Fungal Biology (CMFB) will present the latest, cutting-edge research on the exciting and growing field of molecular and cellular aspects of fungal biology. Topics will range from yeast to filamentous fungi, from model systems to economically important organisms, and from saprophytes and commensals to pathogens of plants and animals. The CMFB conference will feature a wide range of topics including systems biology, cell biology and morphogenesis, organismal interactions, genome organisation and regulation, pathogenesis, energy metabolism, biomass production and population genomics. The Conference was well-attended with 136 participants. Gordon Research Conferences does not permit publication of meeting proceedings.

  4. Tuning of the electro-mechanical behavior of the cellular carbon nanotube structures with nanoparticle dispersions

    SciTech Connect (OSTI)

    Gowda, Prarthana; Misra, Abha; Ramamurty, Upadrasta; Center of Excellence for Advanced Materials Research, King Abdulaziz University, Jeddah 21589

    2014-03-10

    The mechanical and electrical characteristics of cellular network of the carbon nanotubes (CNT) impregnated with metallic and nonmetallic nanoparticles were examined simultaneously by employing the nanoindentation technique. Experimental results show that the nanoparticle dispersion not only enhances the mechanical strength of the cellular CNT by two orders of magnitude but also imparts variable nonlinear electrical characteristics; the latter depends on the contact resistance between nanoparticles and CNT, which is shown to depend on the applied load while indentation. Impregnation with silver nanoparticles enhances the electrical conductance, the dispersion with copper oxide and zinc oxide nanoparticles reduces the conductance of CNT network. In all cases, a power law behavior with suppression in the differential conductivity at zero bias was noted, indicating electron tunneling through the channels formed at the CNT-nanoparticle interfaces. These results open avenues for designing cellular CNT foams with desired electro-mechanical properties and coupling.

  5. Method of forming a continuous polymeric skin on a cellular foam material

    DOE Patents [OSTI]

    Duchane, David V. (Los Alamos, NM); Barthell, Barry L. (Los Alamos, NM)

    1985-01-01

    Hydrophobic cellular material is coated with a thin hydrophilic polymer skin which stretches tightly over the outer surface of the foam but which does not fill the cells of the foam, thus resulting in a polymer-coated foam structure having a smoothness which was not possible in the prior art. In particular, when the hydrophobic cellular material is a specially chosen hydrophobic polymer foam and is formed into arbitrarily chosen shapes prior to the coating with hydrophilic polymer, inertial confinement fusion (ICF) targets of arbitrary shapes can be produced by subsequently coating the shapes with metal or with any other suitable material. New articles of manufacture are produced, including improved ICF targets, improved integrated circuits, and improved solar reflectors and solar collectors. In the coating method, the cell size of the hydrophobic cellular material, the viscosity of the polymer solution used to coat, and the surface tensin of the polymer solution used to coat are all very important to the coating.

  6. Three-dimensional simulations of cellular non-premixed jet flames

    SciTech Connect (OSTI)

    Valaer, A.L.; Frouzakis, C.E.; Boulouchos, K.; Papas, P.; Tomboulides, A.G.

    2010-04-15

    The formation, dynamics and structure of cellular flames in circular non-premixed jets are examined with three-dimensional numerical simulations incorporating detailed descriptions of chemistry and transport. Similar to past experiments reported in the literature, CO{sub 2}-diluted hydrogen in diluted or pure oxygen co-flowing streams in the proximity of the extinction limit are considered. As in the experiments, several preferred cellular states are found to co-exist with the particular state realized depending on initial conditions as well as on the jet characteristics. The simulations provide additionally the temporal transitions to different stationary or rotating cellular flames, their detailed structure, and the dependence of the scaling of the realized number of cells with the vorticity thickness. (author)

  7. Between the poles : locating physics majors in the expert-novice continuum

    E-Print Network [OSTI]

    Gire, Elizabeth Ellen

    2007-01-01

    DISSERTATION Between the Poles: Locating Physics Majors inSAN DIEGO Between the Poles: Locating Physics Majors in the

  8. Piezoelectricity and ferroelectricity of cellular polypropylene electrets films characterized by piezoresponse force microscopy

    SciTech Connect (OSTI)

    Miao, Hongchen; Sun, Yao; Zhou, Xilong; Li, Yingwei; Li, Faxin

    2014-08-14

    Cellular electrets polymer is a new ferroelectret material exhibiting large piezoelectricity and has attracted considerable attentions in researches and industries. Property characterization is very important for this material and current investigations are mostly on macroscopic properties. In this work, we conduct nanoscale piezoelectric and ferroelectric characterizations of cellular polypropylene (PP) films using piezoresponse force microscopy (PFM). First, both the single-frequency PFM and dual-frequency resonance-tracking PFM testings were conducted on the cellular PP film. The localized piezoelectric constant d{sub 33} is estimated to be 7–11pC/N by correcting the resonance magnification with quality factor and it is about one order lower than the macroscopic value. Next, using the switching spectroscopy PFM (SS-PFM), we studied polarization switching behavior of the cellular PP films. Results show that it exhibits the typical ferroelectric-like phase hysteresis loops and butterfly-shaped amplitude loops, which is similar to that of a poly(vinylidene fluoride) (PVDF) ferroelectric polymer film. However, both the phase and amplitude loops of the PP film are intensively asymmetric, which is thought to be caused by the nonzero remnant polarization after poling. Then, the D-E hysteresis loops of both the cellular PP film and PVDF film were measured by using the same wave form as that used in the SS-PFM, and the results show significant differences. Finally, we suggest that the ferroelectric-like behavior of cellular electrets films should be distinguished from that of typical ferroelectrics, both macroscopically and microscopically.

  9. Soliton cellular automaton associated with $G_2^{(1)}$ crystal base

    E-Print Network [OSTI]

    Kailash C. Misra; Masato Okado; Evan A. Wilson

    2011-09-13

    We calculate the combinatorial $R$ matrix for all elements of $\\mathcal{B}_l\\otimes \\mathcal{B}_1$ where $\\mathcal{B}_l$ denotes the $G_2^{(1)}$-perfect crystal of level $l$, and then study the soliton cellular automaton constructed from it. The solitons of length $l$ are identified with elements of the $A_1^{(1)}$-crystal $\\tilde{\\mathcal{B}}_{3l}$. The scattering rule for our soliton cellular automaton is identified with the combinatorial $R$ matrix for $A_1^{(1)}$-crystals.

  10. Impurity-doped optical shock, detonation and damage location sensor

    DOE Patents [OSTI]

    Weiss, J.D.

    1995-02-07

    A shock, detonation, and damage location sensor providing continuous fiber-optic means of measuring shock speed and damage location, and could be designed through proper cabling to have virtually any desired crush pressure. The sensor has one or a plurality of parallel multimode optical fibers, or a singlemode fiber core, surrounded by an elongated cladding, doped along their entire length with impurities to fluoresce in response to light at a different wavelength entering one end of the fiber(s). The length of a fiber would be continuously shorted as it is progressively destroyed by a shock wave traveling parallel to its axis. The resulting backscattered and shifted light would eventually enter a detector and be converted into a proportional electrical signals which would be evaluated to determine shock velocity and damage location. The corresponding reduction in output, because of the shortening of the optical fibers, is used as it is received to determine the velocity and position of the shock front as a function of time. As a damage location sensor the sensor fiber cracks along with the structure to which it is mounted. The size of the resulting drop in detector output is indicative of the location of the crack. 8 figs.

  11. Impurity-doped optical shock, detonation and damage location sensor

    DOE Patents [OSTI]

    Weiss, Jonathan D. (Albuquerque, NM)

    1995-01-01

    A shock, detonation, and damage location sensor providing continuous fiber-optic means of measuring shock speed and damage location, and could be designed through proper cabling to have virtually any desired crush pressure. The sensor has one or a plurality of parallel multimode optical fibers, or a singlemode fiber core, surrounded by an elongated cladding, doped along their entire length with impurities to fluoresce in response to light at a different wavelength entering one end of the fiber(s). The length of a fiber would be continuously shorted as it is progressively destroyed by a shock wave traveling parallel to its axis. The resulting backscattered and shifted light would eventually enter a detector and be converted into a proportional electrical signals which would be evaluated to determine shock velocity and damage location. The corresponding reduction in output, because of the shortening of the optical fibers, is used as it is received to determine the velocity and position of the shock front as a function of time. As a damage location sensor the sensor fiber cracks along with the structure to which it is mounted. The size of the resulting drop in detector output is indicative of the location of the crack.

  12. Method for locating metallic nitride inclusions in metallic alloy ingots

    DOE Patents [OSTI]

    White, Jack C. (Albany, OR); Traut, Davis E. (Corvallis, OR); Oden, Laurance L. (Albany, OR); Schmitt, Roman A. (Corvallis, OR)

    1992-01-01

    A method of determining the location and history of metallic nitride and/or oxynitride inclusions in metallic melts. The method includes the steps of labeling metallic nitride and/or oxynitride inclusions by making a coreduced metallic-hafnium sponge from a mixture of hafnium chloride and the chloride of a metal, reducing the mixed chlorides with magnesium, nitriding the hafnium-labeled metallic-hafnium sponge, and seeding the sponge to be melted with hafnium-labeled nitride inclusions. The ingots are neutron activated and the hafnium is located by radiometric means. Hafnium possesses exactly the proper metallurgical and radiochemical properties for this use.

  13. Adaptation of flexible polymer fabrication to cellular mechanics study Yi Zhao and Xin Zhanga

    E-Print Network [OSTI]

    Polymeric material has been utilized as mechanical sensors to measure microscopic cellular forces. Since a flexible fabrication process to manufacture polymeric mechanical sensors with various aspect ratios from. The results conform to the physiologic behavior. This approach has the potential for evaluation of mechanical

  14. Industry Symposium on Micro and Nano scale Cellular Polymers Department of Mechanical Engineering

    E-Print Network [OSTI]

    Kumar, Vipin

    .00 Gas-Assisted Thermoforming of Recycled PET Stephen Probert and Krishna Nadella 11.30 Porous PolymersIndustry Symposium on Micro and Nano scale Cellular Polymers Department of Mechanical Engineering, College of Engineering Professor Mark Tuttle, Chair, ME 8.30 State of Art of Microcellular Polymers Prof

  15. Power Control for Code Division Multiple Access Cellular Systems Bassam Hashem and Halim Yanikomeroglu

    E-Print Network [OSTI]

    Yanikomeroglu, Halim

    Power Control for Code Division Multiple Access Cellular Systems Bassam Hashem and Halim the interference results in a direct increase in the system capacity. Power control is the most important requirement to reduce the interference. In this work, we show how power control is implemented in current

  16. SpeedBalance: Speed-Scaling-Aware Optimal Load Balancing for Green Cellular Networks

    E-Print Network [OSTI]

    Shihada, Basem

    at base stations (BSs) as they are the key source of heavy energy usage in cellular networks, reported and Bhaskar Krishnamachari Department of Electrical Engineering, Viterbi School of Engineering University for a flexible tradeoff between delay and energy, we first study how to adaptively vary the processing speed

  17. Human Cellular Retinaldehyde-Binding Protein Has Secondary Thermal 9-cis-Retinal Isomerase Activity

    E-Print Network [OSTI]

    Palczewski, Krzysztof

    Human Cellular Retinaldehyde-Binding Protein Has Secondary Thermal 9-cis-Retinal Isomerase Activity molecules in both CRALBP-assisted specificity toward 9-cis-retinal and its thermal isomerase activity opsin receptor molecules into photosensitive retinoid pigments of the eye. We report a thermal secondary

  18. MOLECULAR AND CELLULAR BIOLOGY, 0270-7306/99/$04.00 0

    E-Print Network [OSTI]

    MOLECULAR AND CELLULAR BIOLOGY, 0270-7306/99/$04.00 0 Dec. 1999, p. 8526­8535 Vol. 19, No. 12 show that the SCAN motif functions as an oligomerization domain mediating self an important role in the assembly and function of this newly defined subclass of transcriptional regulators

  19. Discrete Mathematics and Theoretical Computer Science AB(DMCS), 2003, 3142 Cellular Automata for Simulating Molecular

    E-Print Network [OSTI]

    Rasmussen, Steen

    for Simulating Molecular Self-Assembly Martin Nilsson and Steen Rasmussen Los Alamos National Laboratory, Los Alamos, NM 87545, USA. We present a lattice gas technique for simulating molecular self-assembly micelles is formed. Keywords: Cellular Automata, Lattice Gas, Molecular Self-Assembly, Statistical

  20. Journal of Cellular Biochemistry 62:290-301 (1996) Isolation and Characterization of a Novel

    E-Print Network [OSTI]

    De Lozanne, Arturo

    1996-01-01

    . The cells can chemotax, phagocytose, cap crosslinked receptors, and contract normally. However, the 10BH2. Key words: cell division, motility, contraction, myosin, actin, capping, development, mutagenesis- vances in mammalian cells, flies, yeast, fungi, and cellular molds have shed light onto some

  1. An Emerging Concept for 4G+ Wireless Cellular Networks: Terminal Relaying

    E-Print Network [OSTI]

    Yanikomeroglu, Halim

    consider a cellular system in which the wireless terminals (WTs), in addition to transmitting their own signals, act as relays to assist other WTs. In such a system the number of relays scales with the number of WTs offering the system designer significantly more degrees of freedom. However, using WTs as relays

  2. STRA6 is critical for cellular vitamin A uptake and homeostasis

    E-Print Network [OSTI]

    Palczewski, Krzysztof

    STRA6 is critical for cellular vitamin A uptake and homeostasis Jaume Amengual1, Ning Zhang1, Mary; Revised and Accepted May 19, 2014 Vitamin A must be adequately distributed within the body to maintain of the lipophilic vitamin is mediated by the retinol- binding protein, RBP4. Biochemical evidence suggests

  3. System capacity of FTDMA cellular systems G. Caire 1 , R. Knopp 2 and P. Humblet 2

    E-Print Network [OSTI]

    Humblet, Pierre A.

    maximum outage probability. Outage is defined as the event that the mutual information of the interference on a typical urban mobile environment. Keywords --- Cellular system capacity, block­fading channels, outage are obtained as special cases. System capacity is constrained by the maximum allowed outage probability. We

  4. Outage in a Cellular Network Overlaid with an Ad hoc Network: The Uplink Case

    E-Print Network [OSTI]

    Yanikomeroglu, Halim

    Outage in a Cellular Network Overlaid with an Ad hoc Network: The Uplink Case Arshdeep S. Kahlon}@sce.carleton.ca Abstract--We analyze the uplink outage probability at the randomly, but not necessarily independently nor, large-scale power control, and the knowledge of the initial outages in the absence of the secondary

  5. Outage Probability in a Multi-Cellular Network using Alamouti Scheme

    E-Print Network [OSTI]

    Coupechoux, Marceau

    Outage Probability in a Multi-Cellular Network using Alamouti Scheme Dorra Ben Cheikh , Jean to interference plus noise ratio (SINR) or equivalently the outage probability in flat Rayleigh fading. The system power from the interfering base stations. In the first case, a closed- form expression for the outage

  6. Energy, quiescence and the cellular basis of animal life spans Jeffrey A. Stuart , Melanie F. Brown

    E-Print Network [OSTI]

    Stuart, Jeffrey A.

    Review Energy, quiescence and the cellular basis of animal life spans Jeffrey A. Stuart , Melanie F insufficient energy is available to grow and reproduce. Many animals adapt to this challenge by entering in energy sensing that are sensitive to aspects of mitochondrial energy transduction and can be modulated

  7. FABRICATION OF CELLULAR MATERIALS Robert K. Prud'homme, lihan A. Aksay, and Rajeev Garg

    E-Print Network [OSTI]

    Aksay, Ilhan A.

    , minimizing raw materials requirements. Minimizing raw materials is efficient both in terms of the energy conserve on raw materials. In the case of the muscle the foam is water filled and the foot structureFABRICATION OF CELLULAR MATERIALS Robert K. Prud'homme, lihan A. Aksay, and Rajeev Garg Department

  8. A Local Cellular Model for Snow Crystal Growth (preprint) Clifford A. Reiter

    E-Print Network [OSTI]

    Reiter, Clifford A.

    1 A Local Cellular Model for Snow Crystal Growth (preprint) Clifford A. Reiter Department of Mathematics, Lafayette College, Easton, PA, 18042 USA Abstract Snow crystals have a rich diversity of forms. Physical studies have shown that the particular form of a snow crystal is dependent upon the temperature

  9. A Cellular Model for 3-Dimensional Snow Crystallization Faculty of Information & Control Engineering, Shenyang Jianzhu University,

    E-Print Network [OSTI]

    Reiter, Clifford A.

    A Cellular Model for 3-Dimensional Snow Crystallization Chen Ning Faculty of Information & Control Snow crystals are intriguing because they exhibit both symmetry and remarkable diversity. Previous studies have used 2-dimensional models to approximate snow-crystal growth. Here generalizations to three

  10. Cellular/Molecular A Calcium-Induced Calcium Influx Factor, Nitric Oxide,

    E-Print Network [OSTI]

    Newman, Eric A.

    in astrocytes lead to the Ca2 -dependent synthesis of nitric oxide. This in turn stimulates a Ca2 influx pathwayCellular/Molecular A Calcium-Induced Calcium Influx Factor, Nitric Oxide, Modulates the Refilling in astrocytes, we imaged the formation of nitric oxide in cultured murine cortical astrocytes using DAF-FM (4

  11. Thermal Applications of Cellular Lattice Structures Haydn N.G. Wadleya

    E-Print Network [OSTI]

    Wadley, Haydn

    exchanger, f is the coolant density and ( )Lp is the pressure drop per unit length [4]. Any open cell metal exchanger, cellular structure, lattice material, heat transfer. Abstract. Numerous methods have recently heat exchange. In this scenario, heat is transported from a locally heated facesheet through

  12. Morphodynamics of barchan and transverse dunes using a cellular automaton model

    E-Print Network [OSTI]

    Narteau, Clément

    Morphodynamics of barchan and transverse dunes using a cellular automaton model D. Zhang,1 C instability is responsible for the formation of dunes on flat sand beds and the initiation of superimposed bedforms on dune slopes. In transverse dune fields, secondary bedforms increase crestline sinuosity

  13. Sediment Dynamics Simulation via Cellular Automata Artificial Intelligence -SYNOPSIS 1.0 Dr. Juan M. Restrepo

    E-Print Network [OSTI]

    Fatkullin, Ibrahim

    Sediment Dynamics Simulation via Cellular Automata Artificial Intelligence - SYNOPSIS 1.0 Dr. Juan dynamics and artificial intelligence. Sediment Dynamics Sediment dynamics is the physics of sedimentary's work, and proved to be quite a task indeed. Artificial Intelligence Because this research project

  14. EECE 595: SPREAD SPECTRUM COMMUNICATIONS 1 Distributed Power Control in CDMA Cellular

    E-Print Network [OSTI]

    station will corrupt the other signals. Another reason for power control is the battery life time. High of each mobile station. The transmission power of the mobile stations is determined solely on localEECE 595: SPREAD SPECTRUM COMMUNICATIONS 1 Distributed Power Control in CDMA Cellular System Aly El

  15. A Decentralized Sleep Mechanism in Heterogeneous Cellular Networks with QoS Constraints

    E-Print Network [OSTI]

    Tao, Meixia "Melissa"

    band. The strategy is to put high-power macro base stations into sleep mode and offload the users to low-power small base stations or neighboring macro base stations. To do so, we first formulate a joint power control. In cellular networks, the energy consumed by always-on components on base stations (BS

  16. Distributed TV Spectrum Allocation for Cognitive Cellular Network under Game Theoretical

    E-Print Network [OSTI]

    Gross, James

    of TV stations and white base stations, maximum permitted transmit power levels on all channels for each station needs to choose a channel with the maximal permitted power on that channel such that the resulting cellular base stations to utilize TV white spectrum (such base stations referred to as white base stations

  17. Cellular/Molecular ERK1/ERK2 MAPK Signaling is Required to Increase Myelin

    E-Print Network [OSTI]

    Cellular/Molecular ERK1/ERK2 MAPK Signaling is Required to Increase Myelin Thickness Independent for two important signaling molecules, extracelluar signal-regulated protein kinases 1 and 2 (ERK1/ERK2 generated and analyzed two lines of mice lacking both ERK1/ERK2 function specifically in oligodendrocyte

  18. Formation of Self-Supporting Reversible Cellular Networks in Suspensions of Colloids and Liquid Crystals

    E-Print Network [OSTI]

    Schofield, Andrew

    .11-13 (ii) In suspensions of sterically stabilized colloidal particles dispersed in liquid crystalFormation of Self-Supporting Reversible Cellular Networks in Suspensions of Colloids and Liquid, calorimetric findings for liquid crystal/colloid mixtures, heated and cooled up to 13 times, point

  19. Cellular/Molecular Light Adaptation in Salamander L-Cone Photoreceptors

    E-Print Network [OSTI]

    Rieke, Fred

    Cellular/Molecular Light Adaptation in Salamander L-Cone Photoreceptors Frederick S. Soo, Peter B,andanincreaseinguanylatecyclaseactivityduringthelightstepthatpersistsafterthelight is extinguished. Key words: photoreceptor; phototransduction; cone adaptation; retina adaptation; light; vision, Washington 98195 The responses of individual salamander L-cones to light steps of moderate intensity

  20. The Cellular Basis for Lack of Antibody Response to Hepatitis B Vaccine In Humans

    E-Print Network [OSTI]

    Alper, Chester A.

    The Cellular Basis for Lack of Antibody Response to Hepatitis B Vaccine In Humans By E. Egea,"S A response to hepatitis B surface antigen (HBsAg) was bimodally distributed with about 14% of subjects), and streptococcal cell wall 'Abbreviations used in this paper HB, hepatitis B; HB&Ag, hepatitis B surface antigen

  1. Greening Effect of Spatio-Temporal Power Sharing Policies in Cellular Networks with Energy Constraints

    E-Print Network [OSTI]

    Yi, Yung

    1 Greening Effect of Spatio-Temporal Power Sharing Policies in Cellular Networks with Energy greening, from which we first develop four IM schemes governed by different power sharing: no sharing, only the spatial and/or temporal power sharing policies, (ii) tighter greening regulation (i.e., smaller total

  2. Limiting Power Transmission of Green Cellular Networks: Impact on Coverage and Capacity

    E-Print Network [OSTI]

    Coupechoux, Marceau

    Limiting Power Transmission of Green Cellular Networks: Impact on Coverage and Capacity Jean potential risks on human health. For these reasons, power control appears to be the main feature of green Issy-Les-Moulineaux, France frederic.marache@orange-ftgroup.com Abstract--Reducing power transmission

  3. Integrated Cellular and Gene Interaction Model for Cell Migration in Embryonic Development

    E-Print Network [OSTI]

    Song, Joe

    Integrated Cellular and Gene Interaction Model for Cell Migration in Embryonic Development Hien Nguyen and Mingzhou (Joe) Song Department of Computer Science New Mexico State University Las Cruces, NM, cells have their own operations, including mitosis, migration, communication with other cells, and death

  4. The cellular basis for parallel neural transmission of a high-frequency stimulus and its

    E-Print Network [OSTI]

    Benda, Jan

    The cellular basis for parallel neural transmission of a high-frequency stimulus and its low-frequency envelopes of high-frequency signals and also suggest that information about stimuli and their envelopes take EOD frequencies will generate a high-frequency envelope of their EOD that is referred

  5. Alkaline phosphatase, a biochemical marker of cellular differentiation of BeWo choriocarcinoma cell line 

    E-Print Network [OSTI]

    Lu, Wei

    1997-01-01

    Cellular copper homeostasis depends on a Cu-ATPase enzyme in the membrane. Surprisingly, flask-grown BeWo cells do not display ATPase. We found Cu-ATPase is only expressed in differentiated cells such as Caco-2 cells. Since BeWo cells...

  6. Channel-Sharing Strategies in Two-Tier Cellular PCS Systems

    E-Print Network [OSTI]

    Tseng, Yu-Chee

    strategies. Keywords: cellular network, channel management, load balance, personal communication system, two and microcells in the service area. This overlapping property provides an advantage that traĆc loads can be shared by the two tiers to increase the performance of the system. In this paper, we propose two channel

  7. A Pricing Based Algorithm for Cell Switching Off in Green Cellular Networks

    E-Print Network [OSTI]

    Yanikomeroglu, Halim

    A Pricing Based Algorithm for Cell Switching Off in Green Cellular Networks Ali Yildiz and Tolga--In this study, we propose a pricing based algorithm that assigns user terminals (UTs) to base stations (BSs) and optimizes the transmission powers in a way that minimizes the energy expenditure. The algorithm takes

  8. In vivo imaging of C. elegans ASH neurons: cellular response and adaptation to chemical repellents

    E-Print Network [OSTI]

    Schafer, William R.

    In vivo imaging of C. elegans ASH neurons: cellular response and adaptation to chemical repellents di Genetica e Biofisica--ABT, Napoli, Italy ASH sensory neurons are required in Caenorhabditis and nose touch. The ASH neurons are therefore hypothesized to be polymodal nociceptive neurons

  9. Trabecular Bone Structure and Cellular Morphology in the Primate Craniofacial Skeleton 

    E-Print Network [OSTI]

    Pryor, Leslie Claire

    2015-08-14

    BONE STRUCTURE AND CELLULAR MORPHOLOGY IN THE PRIMATE CRANIOFACIAL SKELETON A Dissertation by LESLIE CLAIRE PRYOR Submitted to the Office of Graduate and Professional Studies of Texas A&M University in partial fulfillment... Emet Schneiderman David Strait Head of Department, Paul C. Dechow August 2015 Major Subject: Biomedical Sciences Copyright 2015 Leslie Claire Pryor ii ABSTRACT The primate craniofacial skeleton is complex...

  10. Dynamic Computational Model Suggests That Cellular Citizenship Is Fundamental for Selective Tumor

    E-Print Network [OSTI]

    Siegelmann , Hava T

    , University of Massachusetts Amherst, Amherst, Massachusetts, United States of America, 2 Communi by proliferation rates, initial volumes, and apoptosis resistant phenotypes; they show high adaptability as at least 32% of cells obey extra-cellular commands and at least 28% of cancer cells report their deaths

  11. Cellular/Molecular Rolling Blackout Is Required for Synaptic Vesicle Exocytosis

    E-Print Network [OSTI]

    Broadie, Kendal S.

    Cellular/Molecular Rolling Blackout Is Required for Synaptic Vesicle Exocytosis Fu-De Huang, Elvin 37235-1634 Rolling blackout (RBO) is a putative transmembrane lipase required for phospholipase C; Kidokoro et al., 2004). We report here a new TS paralytic mutant, rolling blackout (rbo), which similarly

  12. Community Detection in Cellular Network Traces Mariya Zheleva, Paul Schmitt, Morgan Vigil and Elizabeth Belding

    E-Print Network [OSTI]

    Belding-Royer, Elizabeth M.

    of Facebook traffic analysis, Johnson et al. designed a system to facilitate local content sharing within an actual need in the community. Analysis of large scale datasets generated by the targeted communities naturally facilitates the identification of actual community needs. We approach a cellular network dataset

  13. Cellular Automata Segmentation of Brain Tumors on Post Contrast MR Images

    E-Print Network [OSTI]

    Yanikoglu, Berrin

    Cellular Automata Segmentation of Brain Tumors on Post Contrast MR Images Andac Hamamci1 , Gozde proposed a complete tumor segmenta- tion method on post contrast T1 MR images, which standardizes the VOI Unal1 , Nadir Kucuk2 , and Kayihan Engin2 1 Faculty of Engineering and Natural Sciences, Sabanci

  14. Cellular/Molecular Mechanisms of Transport and Exocytosis of Dense-Core

    E-Print Network [OSTI]

    Silverman, Michael

    Cellular/Molecular Mechanisms of Transport and Exocytosis of Dense-Core Granules Containing Tissue of Biological Sciences, California State Polytechnic University, Pomona, California 91768, Departments of 2 microscopy, in conjunction with transport theory, to visualize the transport and exocytosis of DCGs

  15. Autotransporters: The Cellular Environment Reshapes a Folding Mechanism to Promote Protein Transport

    E-Print Network [OSTI]

    Clark, Patricia L.

    the cellular environment affects protein folding mechanisms. Here, we focus on one unique aspect affect protein folding kinetics and the conformations of folding intermediates? We focus on recent have been made to understand the mechanisms by which proteins fold to their native conformations.3

  16. Table 1. HARVESTING MANAGEMENT STRATEGIES Strategy Name Use Typical location

    E-Print Network [OSTI]

    Table 1. HARVESTING MANAGEMENT STRATEGIES Strategy Name Use Typical location Harvesting strategies Unstable gullies with debris flow potential, unstable channels with high water transport, unstable fans by water flows Channels with high or moderate water transport potential Clean large woody debris /CLWD

  17. Search strategies for Java bottleneck location by dynamic instrumentation

    E-Print Network [OSTI]

    Kelly, Paul H. J.

    instrumentation within a Java Virtual Ma- chine. Several options are available; our implementation used our VeneerSearch strategies for Java bottleneck location by dynamic instrumentation Douglas J Brear, Thibaut investigation of this interesting approach. 1 Introduction The idea of dynamically patching instrumentation code

  18. Short Communication Occasional changes in sound location enhance middle

    E-Print Network [OSTI]

    Trainor, Laurel J.

    changes in auditory location information are processed in areas beyond primary auditory cortex. Our data information, perhaps in parallel with the processing of information regarding the nature of the sound source suggest that any such processing is in fact preceded by activation in primary auditory cortex. © 2005

  19. A Neural Network for Locating the Primary Vertex in

    E-Print Network [OSTI]

    Kantowski, Ron

    A Neural Network for Locating the Primary Vertex in a Pixel Detector R. Kantowski and Caren Marzban, a neural network is trained to construct the coordinate of the primary vertex to a high degree of accuracy. Three other estimates of this coordinate are also considered and compared to that of the neural network

  20. Neural Network Approach to Locating Cryptography in Object Code

    SciTech Connect (OSTI)

    Jason L. Wright; Milos Manic

    2009-09-01

    Finding and identifying cryptography is a growing concern in the malware analysis community. In this paper, artificial neural networks are used to classify functional blocks from a disassembled program as being either cryptography related or not. The resulting system, referred to as NNLC (Neural Net for Locating Cryptography) is presented and results of applying this system to various libraries are described.

  1. SLIM: A Scalable Location-Sensitive Information Monitoring Service

    E-Print Network [OSTI]

    Liu, Ling

    . A typical example of such services is "alert me when the gas price at a gas station within 5 miles of my current location drops to $4 per gallon". Such a service needs to monitor the gas price changes gas prices at gas stations, traffic conditions at major junctions or pollution levels in different

  2. The Smart Party: A Personalized Location-aware Multimedia Experience

    E-Print Network [OSTI]

    California at Los Angeles, University of

    of the Smart Party, a group of people attend a gathering hosted at someone's home. Each person carries a smallThe Smart Party: A Personalized Location-aware Multimedia Experience Kevin Eustice, V. Ramakrishna Angeles, California {kfe,vrama,songuku,reiher}@cs.ucla.edu Abstract-- We describe the Smart Party, a new

  3. Icarus 182 (2006) 343349 www.elsevier.com/locate/icarus

    E-Print Network [OSTI]

    California at Berkeley, University of

    2006-01-01

    radiation, charge-exchange or electron-impact processes can be effectively picked up by the solar windIcarus 182 (2006) 343­349 www.elsevier.com/locate/icarus Solar wind plasma protrusion composition from a solar wind plasma to a planetary plasma dominated by oxygen ions. A possible mechanism

  4. MICROSIMULATION OF RESIDENTIAL LAND DEVELOPMENT AND HOUSEHOLD LOCATION CHOICES

    E-Print Network [OSTI]

    Kockelman, Kara M.

    maximization and bid-rent theory, this paper investigates single-family residential location choices of new distribution). On the demand side, individual households (characterized by size, income, and presence and land owners maximize profits and/or rents. The simulation analysis offers insights into key features

  5. Multi-node Coordinated Jamming for Location Privacy Protection

    E-Print Network [OSTI]

    Gruteser, Marco

    precisely locate the target nodes. Although basic anti-localization techniques based on power control's localization systems. However, such a jamming technique has the problem of interfering with the communication such interference problems, those techniques generally induce co- ordination problems or require encryption

  6. Using Manager Self Service Reporting and Location Changes

    E-Print Network [OSTI]

    Leistikow, Bruce N.

    Using Manager Self Service Reporting and Location Changes Note: For staff employees, the new supervisor must have a manager or supervisory title. For academic employees, the new supervisor will be the administrator of record and must have eHR access. To use Manager Self Service: click on the Manager Self Service

  7. Lab 4: Plate Tectonics Locating Geologic Hazards Introduction

    E-Print Network [OSTI]

    Chen, Po

    1 Lab 4: Plate Tectonics ­ Locating Geologic Hazards Introduction The likelihood of major geologic hazards associated with the lithosphere, such as earthquakes and volcanoes, is not uniform around provides a ready explanation for the distribution of these types of geologic hazards. It is useful

  8. Icarus 196 (2008) 216224 www.elsevier.com/locate/icarus

    E-Print Network [OSTI]

    2008-01-01

    Icarus 196 (2008) 216­224 www.elsevier.com/locate/icarus Resurfacing of Titan by ammonia-water latitudes [Lopes, R.M.C., and 43 colleagues, 2007. Icarus 186, 395­412]. To date, models of ammonia-water of cryovolcanism that involves cracking at the base of the ice shell and formation of ammonia-water pockets

  9. Visualizing Conserved Gene Location across Microbe Chris D Shaw

    E-Print Network [OSTI]

    Shaw, Chris

    Visualizing Conserved Gene Location across Microbe Genomes Chris D Shaw School of Interactive Arts of microbes. The purpose of this visualizatiuon is to enable a biologist to examine the layout of genes help a biologist better confirm the structure and function of newly analyzed microbe DNA sequences. We

  10. Toward Urban Model Acquisition from Geo-Located Images

    E-Print Network [OSTI]

    Teller, Seth

    a novel sensor, and as- sociated geometric algorithms, to achieve fully automated reconstruction from close-range color images of textured geometric models representing built urban structures. The sensor is a geo-located camera, which annotates each acquired digital image with metadata recording the date

  11. Enhancing Location Privacy for Electric Vehicles (at the right time)

    E-Print Network [OSTI]

    International Association for Cryptologic Research (IACR)

    Enhancing Location Privacy for Electric Vehicles (at the right time) Joseph K. Liu1 , Man Ho Au2 University of Wollongong, Australia {aau, wsusilo}@uow.edu.au Abstract. An electric vehicle is a promising of electric vehicles at the right time, by proposing an anonymous payment system with privacy protection

  12. Optimal Location of a Mobile Sensor Continuum for Environmental Monitoring

    E-Print Network [OSTI]

    Boyer, Edmond

    air pollution monitoring, seismic monitoring, or monitoring of large infrastructures in civil is proposed for the goal of optimal location of a mobile sensor continuum. The monitoring of pollution on a 2D or track distributed environmental phenomena (weather, seismic events, wildfires, air, soil or river

  13. Derivation of Locational Marginal Prices for Restructured Wholesale Power Markets

    E-Print Network [OSTI]

    Tesfatsion, Leigh

    the performance of these markets. In this paper, different AC and DC optimal power flow (OPF) models are presented Operator (MISO). Keywords: Locational marginal pricing, wholesale power market, AC optimal power flow, DC optimal power flow, U.S. Midwest Independent System Operator (MISO). #12;3 1 INTRODUCTION In an April 2003

  14. An Efficient Hierarchical Scheme for Locating Highly Mobile Users \\Lambda

    E-Print Network [OSTI]

    Fudos, Ioannis

    on the maximum number of the forwarding pointers and the other on the distance of the move. In addition, we, a scheme based on forwarding pointers is presented, that reduces the cost of the overall network the number of forwarding pointers that need to be traversed to locate a user, auxiliary caching techniques

  15. COGNITIVE TOOLS FOR LOCATING AND COMPREHENDING SOFTWARE OBJECTS

    E-Print Network [OSTI]

    Fischer, Gerhard

    COGNITIVE TOOLS FOR LOCATING AND COMPREHENDING SOFTWARE OBJECTS FOR REUSE Gerhard Fischer Scott Henninger David Redmiles Repnn ed from PROCEEDINGS OF THE 13TH ITER ATIONAL CONFERE CE ON SOFTWARE E GI EERI of Cognitive Science University of Colorado Boulder, Colorado 80309 Abstract Software reuse is the process

  16. Low Cost Intelligent Pervasive Location Tracking (iPLOT)

    E-Print Network [OSTI]

    devices within ad-hoc networks of static and mobile users and equipment. The `nodes' of the network could ranges (distances) between devices from a system that is designed for mobile communications communications technology to provide continuous tracking of the location of devices in all environments

  17. Context-based Personalised Settings for Mobile Location Sharing

    E-Print Network [OSTI]

    Henderson, Tristan

    is currently done through static settings for most popular Social Network Sites (SNSes) such as Facebook. Nonetheless, LBS settings are usually static, not only for Facebook or Google+'s location-sharing features better cope with users' actual shar- ing preferences than static settings. Using data collected from

  18. The Influence of Locative Media on Social Information Edwin Keijl

    E-Print Network [OSTI]

    Theune, Mariët

    on Facebook attracted 25.000 people on a very short notice and left a small town in The Netherlands ravaged the most popular geo-tagging services are Facebook, Foursquare, Twitter, Google Lati- tude and Flickr [29 is to look at the actual effects of locative media reported in these articles. We conclude by answering our

  19. Analytical extraction of the recombination zone location in organic

    E-Print Network [OSTI]

    Tessler, Nir

    Analytical extraction of the recombination zone location in organic light-emitting diodes from emission patterns produced by organic LEDs (OLEDs). The method is based on derivation of the closed-form expressions for OLED-radiated power developed in previous work and formulation of the analytical relations

  20. INTERNATIONAL JOURNAL OF WIRELESS AND MOBILE COMPUTING 1 Effective Location-Guided Overlay Multicast in

    E-Print Network [OSTI]

    Nahrstedt, Klara

    INTERNATIONAL JOURNAL OF WIRELESS AND MOBILE COMPUTING 1 Effective Location-Guided Overlay: location-guided k-ary (LGK) tree, location-guided directional (LGD) tree, and location-guided Steiner (LGS. To augment and enhance our location- guided tree construction algorithms, we propose several companion

  1. Cellular response to low dose radiation: Role of phosphatidylinositol-3 kinase like kinases

    SciTech Connect (OSTI)

    Balajee, A.S.; Meador, J.A.; Su, Y.

    2011-03-24

    It is increasingly realized that human exposure either to an acute low dose or multiple chronic low doses of low LET radiation has the potential to cause different types of cancer. Therefore, the central theme of research for DOE and NASA is focused on understanding the molecular mechanisms and pathways responsible for the cellular response to low dose radiation which would not only improve the accuracy of estimating health risks but also help in the development of predictive assays for low dose radiation risks associated with tissue degeneration and cancer. The working hypothesis for this proposal is that the cellular mechanisms in terms of DNA damage signaling, repair and cell cycle checkpoint regulation are different for low and high doses of low LET radiation and that the mode of action of phosphatidylinositol-3 kinase like kinases (PIKK: ATM, ATR and DNA-PK) determines the dose dependent cellular responses. The hypothesis will be tested at two levels: (I) Evaluation of the role of ATM, ATR and DNA-PK in cellular response to low and high doses of low LET radiation in simple in vitro human cell systems and (II) Determination of radiation responses in complex cell microenvironments such as human EpiDerm tissue constructs. Cellular responses to low and high doses of low LET radiation will be assessed from the view points of DNA damage signaling, DNA double strand break repair and cell cycle checkpoint regulation by analyzing the activities (i.e. post-translational modifications and kinetics of protein-protein interactions) of the key target proteins for PI-3 kinase like kinases both at the intra-cellular and molecular levels. The proteins chosen for this proposal are placed under three categories: (I) sensors/initiators include ATM ser1981, ATR, 53BP1, gamma-H2AX, MDC1, MRE11, Rad50 and Nbs1; (II) signal transducers include Chk1, Chk2, FANCD2 and SMC1; and (III) effectors include p53, CDC25A and CDC25C. The primary goal of this proposal is to elucidate the differences in cellular defense mechanisms between low and high doses of low LET radiation and to define the radiation doses where the cellular DNA damage signaling and repair mechanisms tend to shift. This information is critically important to address and advance some of the low dose research program objectives of DOE. The results of this proposed study will lead to a better understanding of the mechanisms for the cellular responses to low and high doses of low LET radiation. Further, systematic analysis of the role of PIKK signaling pathways as a function of radiation dose in tissue microenvironment will provide useful mechanistic information for improving the accuracy of radiation risk assessment for low doses. Knowledge of radiation responses in tissue microenvironment is important for the accurate prediction of ionizing radiation risks associated with cancer and tissue degeneration in humans.

  2. Helicopter Surveys for Locating Wells and Leaking Oilfield Infrastructure

    SciTech Connect (OSTI)

    Hammack, R.W.; Veloski, G.A.; Hodges, G. (Fugro Airborne Surveys)

    2006-10-01

    Prior to the injection of CO2 into geological formations, either for enhanced oil recovery or for CO2 sequestration, it is necessary to locate wells that perforate the target formation and are within the radius of influence for planned injection wells. Locating and plugging wells is necessary because improperly plugged well bores provide the most rapid route for CO2 escape to the surface. This paper describes the implementation and evaluation of helicopter and ground-based well detection strategies at a 100+ year old oilfield in Wyoming where a CO2 flood is planned. This project was jointly funded by the U.S. Department of Energy’s National Energy Technology Laboratory and Fugro Airborne Surveys

  3. Location and identification of radioactive waste in Massachusetts Bay

    SciTech Connect (OSTI)

    Colton, D.P.; Louft, H.L.

    1993-12-31

    The accurate location and identification of hazardous waste materials dumped in the world`s oceans are becoming an increasing concern. For years, the oceans have been viewed as a convenient and economical place to dispose of all types of waste. In all but a few cases, major dump sites have been closed leaving behind years of accumulated debris. The extent of past environmental damage, the possibility of continued environmental damage, and the possibility of hazardous substances reaching the human food chain need to be carefully investigated. This paper reports an attempt to accurately locate and identify the radioactive component of the waste material. The Department of Energy`s Remote Sensing Laboratory (RSL), in support of the US Environmental Protection Agency (EPA), provided the precision navigation system and prototype underwater radiological monitoring equipment that were used during this project. The paper also describes the equipment used, presents the data obtained, and discusses future equipment development.

  4. Load cell having strain gauges of arbitrary location

    DOE Patents [OSTI]

    Spletzer, Barry (Albuquerque, NM)

    2007-03-13

    A load cell utilizes a plurality of strain gauges mounted upon the load cell body such that there are six independent load-strain relations. Load is determined by applying the inverse of a load-strain sensitivity matrix to a measured strain vector. The sensitivity matrix is determined by performing a multivariate regression technique on a set of known loads correlated to the resulting strains. Temperature compensation is achieved by configuring the strain gauges as co-located orthogonal pairs.

  5. Location of the essential spectrum in curved quantum layers

    SciTech Connect (OSTI)

    Krej?i?ík, David; Lu, Zhiqin

    2014-08-15

    We consider the Dirichlet Laplacian in tubular neighbourhoods of complete non-compact Riemannian manifolds immersed in the Euclidean space. We show that the essential spectrum coincides with the spectrum of a planar tube provided that the second fundamental form of the manifold vanishes at infinity and the transport of the cross-section along the manifold is asymptotically parallel. For low dimensions and codimension, the result applies to the location of propagating states in nanostructures under physically natural conditions.

  6. Alternative Fuels Data Center: Ethanol Fueling Station Locations

    Alternative Fuels and Advanced Vehicles Data Center [Office of Energy Efficiency and Renewable Energy (EERE)]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels Data Center Home PageBlender Pump Dispensers toStation Locations to someone by

  7. Alternative Fuels Data Center: Natural Gas Fueling Station Locations

    Alternative Fuels and Advanced Vehicles Data Center [Office of Energy Efficiency and Renewable Energy (EERE)]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels Data Center Home PageBlender Pump DispensersEmergingMinneapolisStation Locations

  8. Locating PHEV exchange stations in V2G

    SciTech Connect (OSTI)

    Pan, Feng; Bent, Russell; Berscheid, Alan; Izraelevitz, David

    2010-01-01

    Plug-in hybrid electric vehicle (PREV) is an environment friendly modem transportation method and has been rapidly penetrate the transportation system. Renewable energy is another contributor to clean power but the associated intermittence increases the uncertainty in power generation. As a foreseen benefit of a vchicle-to-grid (V2G) system, PREV supporting infrastructures like battery exchange stations can provide battery service to PREV customers as well as being plugged into a power grid as energy sources and stabilizer. The locations of exchange stations are important for these two objectives under constraints from both ,transportation system and power grid. To model this location problem and to understand and analyze the benefit of a V2G system, we develop a two-stage stochastic program to optimally locate the stations prior to the realizations of battery demands, loads, and generation capacity of renewable power sources. Based on this model, we use two data sets to construct the V2G systems and test the benefit and the performance of these systems.

  9. Computational up-scaling of anisotropic swelling and mechanical behavior of hierarchical cellular material

    E-Print Network [OSTI]

    Rafsanjani, Ahmad; Wittel, Falk K; Carmeliet, Jan

    2015-01-01

    The hygro-mechanical behavior of a hierarchical cellular material, i.e. growth rings of softwood is investigated using a two-scale micro-mechanics model based on a computational homogenization technique. The lower scale considers the individual wood cells of varying geometry and dimensions. Honeycomb unit cells with periodic boundary conditions are utilized to calculate the mechanical properties and swelling coefficients of wood cells. Using the cellular scale results, the anisotropy in mechanical and swelling behavior of a growth ring in transverse directions is investigated. Predicted results are found to be comparable to experimental data. It is found that the orthotropic swelling properties of the cell wall in thin-walled earlywood cells produce anisotropic swelling behavior while, in thick latewood cells, this anisotropy vanishes. The proposed approach provides the ability to consider the complex microstructure when predicting the effective mechanical and swelling properties of softwood.

  10. Dynamics of Cell Shape and Forces on Micropatterned Substrates Predicted by a Cellular Potts Model

    E-Print Network [OSTI]

    Philipp J. Albert; Ulrich S. Schwarz

    2014-05-19

    Micropatterned substrates are often used to standardize cell experiments and to quantitatively study the relation between cell shape and function. Moreover, they are increasingly used in combination with traction force microscopy on soft elastic substrates. To predict the dynamics and steady states of cell shape and forces without any a priori knowledge of how the cell will spread on a given micropattern, here we extend earlier formulations of the two-dimensional cellular Potts model. The third dimension is treated as an area reservoir for spreading. To account for local contour reinforcement by peripheral bundles, we augment the cellular Potts model by elements of the tension-elasticity model. We first parameterize our model and show that it accounts for momentum conservation. We then demonstrate that it is in good agreement with experimental data for shape, spreading dynamics, and traction force patterns of cells on micropatterned substrates. We finally predict shapes and forces for micropatterns that have not yet been experimentally studied.

  11. Phenylbutyric acid induces the cellular senescence through an Akt/p21{sup WAF1} signaling pathway

    SciTech Connect (OSTI)

    Kim, Hag Dong; Jang, Chang-Young; Choe, Jeong Min; Department of Biochemistry, Korea University College of Medicine, Seoul 136-705; Korean Institute of Molecular Medicine and Nutrition, Seoul 136-705 ; Sohn, Jeongwon; Korean Institute of Molecular Medicine and Nutrition, Seoul 136-705 ; Kim, Joon

    2012-06-01

    Highlights: Black-Right-Pointing-Pointer Phenylbutyric acid induces cellular senescence. Black-Right-Pointing-Pointer Phenylbutyric acid activates Akt kinase. Black-Right-Pointing-Pointer The knockdown of PERK also can induce cellular senescence. Black-Right-Pointing-Pointer Akt/p21{sup WAF1} pathway activates in PERK knockdown induced cellular senescence. -- Abstract: It has been well known that three sentinel proteins - PERK, ATF6 and IRE1 - initiate the unfolded protein response (UPR) in the presence of misfolded or unfolded proteins in the ER. Recent studies have demonstrated that upregulation of UPR in cancer cells is required to survive and proliferate. Here, we showed that long exposure to 4-phenylbutyric acid (PBA), a chemical chaperone that can reduce retention of unfolded and misfolded proteins in ER, induced cellular senescence in cancer cells such as MCF7 and HT1080. In addition, we found that treatment with PBA activates Akt, which results in p21{sup WAF1} induction. Interestingly, the depletion of PERK but not ATF6 and IRE1 also induces cellular senescence, which was rescued by additional depletion of Akt. This suggests that Akt pathway is downstream of PERK in PBA induced cellular senescence. Taken together, these results show that PBA induces cellular senescence via activation of the Akt/p21{sup WAF1} pathway by PERK inhibition.

  12. In vivo imaging of C. elegans ASH neurons: cellular response and adaptation to chemical repellents

    E-Print Network [OSTI]

    Schafer, William R.

    Erratum In vivo imaging of C. elegans ASH neurons: cellular response and adaptation to chemical (arbitrary units) Intensity 10 mM copper 3 s 2 s 1 s 0 s -1 s 1.6 2.1 m)µ( YFP CFP Dendrite Soma ASH Time (s following panels. Scale bar, 200 mm. (B) Diagram of the animal's head with one of the two symmetrical ASH

  13. Mean time of archipelagos in $1D$ probabilistic cellular automata has phases

    E-Print Network [OSTI]

    A. D. Ramos

    2014-12-12

    We study a non-ergodic one-dimensional probabilistic cellular automata, where each component can assume the states $\\+$ and $\\-.$ We obtained the limit distribution for a set of measures on $\\{\\+,\\-\\}^\\Z.$ Also, we show that for certain parameters of our process the mean time of convergence can be finite or infinity. When it is finite we have showed that the upper bound is function of the initial distribution.

  14. Advanced Cellular and Biomolecular Imaging at Lehigh University, (PA) Final Scientific/Technical Report

    SciTech Connect (OSTI)

    Cassimeris, Lynne, U.

    2010-09-10

    Lehigh University is establishing an interdisciplinary program in high resolution cellular and subcellular biological imaging for a range of applications including improved cancer detection. The completed DOE project added to Lehigh?s bio-imaging infrastructure through acquisition of a new confocal microscope system as well as upgrades to two pieces of existing equipment. Bio-imaging related research at Lehigh was also supported through two seed grants for initiation of new projects.

  15. Human Homolog of Drosophila Ariadne (HHARI) is a marker of cellular proliferation associated with nuclear bodies

    SciTech Connect (OSTI)

    Elmehdawi, Fatima; Wheway, Gabrielle; Szymanska, Katarzyna; Adams, Matthew; High, Alec S.; Johnson, Colin A.; Robinson, Philip A.

    2013-02-01

    HHARI (also known as ARIH1) is an ubiquitin-protein ligase and is the cognate of the E2, UbcH7 (UBE2L3). To establish a functional role for HHARI in cellular proliferation processes, we performed a reverse genetics screen that identified n=86/522 (16.5%) ubiquitin conjugation components that have a statistically significant effect on cell proliferation, which included HHARI as a strong hit. We then produced and validated a panel of specific antibodies that establish HHARI as both a nuclear and cytoplasmic protein that is expressed in all cell types studied. HHARI was expressed at higher levels in nuclei, and co-localized with nuclear bodies including Cajal bodies (p80 coilin, NOPP140), PML and SC35 bodies. We confirmed reduced cellular proliferation after ARIH1 knockdown with individual siRNA duplexes, in addition to significantly increased levels of apoptosis, an increased proportion of cells in G2 phase of the cell cycle, and significant reductions in total cellular RNA levels. In head and neck squamous cell carcinoma biopsies, there are higher levels of HHARI expression associated with increased levels of proliferation, compared to healthy control tissues. We demonstrate that HHARI is associated with cellular proliferation, which may be mediated through its interaction with UbcH7 and modification of proteins in nuclear bodies. -- Highlights: ? We produce and validate new antibody reagents for the ubiquitin-protein ligase HHARI. ? HHARI colocalizes with nuclear bodies including Cajal, PML and SC35 bodies. ? We establish new functions in cell proliferation regulation for HHARI. ? Increased HHARI expression associates with squamous cell carcinoma and proliferation.

  16. Where the Rubber Meets the Road-- the Alternative Fuel Station Locator

    Broader source: Energy.gov [DOE]

    To use the Alternative Fuel Station Locator, travelers with alternative fuel vehicles just enter their address alternative fuel station locator mobile and pick their fuel.

  17. GIM3E: Condition-specific Models of Cellular Metabolism Developed from Metabolomics and Expression Data

    SciTech Connect (OSTI)

    Schmidt, Brian; Ebrahim, Ali; Metz, Thomas O.; Adkins, Joshua N.; Palsson, Bernard O.; Hyduke, Daniel R.

    2013-11-15

    Motivation: Genome-scale metabolic models have been used extensively to investigate alterations in cellular metabolism. The accuracy of these models to represent cellular metabolism in specific conditions has been improved by constraining the model with omics data sources. However, few practical methods for integrating metabolomics data with other omics data sources into genome-scale models of metabolism have been reported. Results: GIMMME (Gene Inactivation Moderated by Metabolism, Metabolomics, and Expression) is an algorithm that enables the development of condition-specific models based on an objective function, transcriptomics, and intracellular metabolomics data. GIMMME establishes metabolite utilization requirements with metabolomics data, uses model-paired transcriptomics data to find experimentally supported solutions, and also provides calculations of the turnover (production / consumption) flux of metabolites. GIMMME was employed to investigate the effects of integrating additional omics datasets to create increasingly constrained solution spaces of Salmonella Typhimurium metabolism during growth in both rich and virulence media. This integration proved to be informative and resulted in a requirement of additional active reactions (12 in each case) or metabolites (26 or 29, respectively). The addition of constraints from transcriptomics also impacted the allowed solution space, and the cellular metabolites with turnover fluxes that were necessarily altered by the change in conditions increased from 118 to 271 of 1397. Availability: GIMMME has been implemented in Python and requires a COBRApy 0.2.x. The algorithm and sample data described here are freely available at: http://opencobra.sourceforge.net/

  18. Cellular oncogene expression following exposure of mice to {gamma}-rays

    SciTech Connect (OSTI)

    Anderson, A.; Woloschak, G.E.

    1991-06-12

    We examined the effects of total body exposure of BCF1 mice to {gamma}-rays (300 cGy) in modulating expression of cellular oncogenes in both gut and liver tissues. We selected specific cellular oncogenes (c-fos, c-myc, c-src, and c-H-ras), based on their normal expression in liver and gut tissues from untreated mice. As early as 5 min. following whole body exposure of BCF1 mice to {gamma}-rays we detected induction of mRNA specific for c-src and c-H-ras in both liver and gut tissues. c-fos RNA was slightly decreased in accumulation in gut but was unaffected in liver tissue from irradiated mice relative to untreated controls. c-myc mRNA accumulation was unaffected in all tissues examined. These experiments document that modulation of cellular oncogene expression can occur as an early event in tissues following irradiation and suggest that this modulation may play a role in radiation-induced carcinogenesis.

  19. A cellular automaton identification of the universality classes of spatiotemporal intermittency

    E-Print Network [OSTI]

    Zahera Jabeen; Neelima Gupte

    2007-07-05

    The phase diagram of the coupled sine circle map lattice shows spatio-temporal intermittency of two distinct types: spatio-temporal intermittency of the directed percolation (DP) class, and spatial intermittency which does not belong to this class. These two types of behaviour are seen to be special cases of the spreading and non-spreading regimes seen in the system. In the spreading regime, each site can infect its neighbours permitting an initial disturbance to spread, whereas in the non-spreading regime no infection is possible. The two regimes are separated by a line which we call the infection line. The coupled map lattice can be mapped on to an equivalent cellular automaton which shows a transition from a probabilistic cellular automaton (PCA) to a deterministic cellular automaton (DCA) at the infection line. Thus the existence of the DP and non-DP universality classes in the same system is signalled by the PCA to DCA transition. We also discuss the dynamic origin of this transition.

  20. Cellular Toxicity Induced by the Photorelease of a Caged Bioactive Molecule: Design of a Potential Dual-Action Ru(II) Complex

    E-Print Network [OSTI]

    Turro, Claudia

    Cellular Toxicity Induced by the Photorelease of a Caged Bioactive Molecule: Design of a Potential one CH3CN ligand in the complex under the irradiation conditions used for the cellular studies. Strategies are being sought to increase the quantum yields of ligand exchange and the cellular penetration

  1. Cellular Biology at the University of Utah The Department of Biology at the University of Utah invites applications for a tenure-

    E-Print Network [OSTI]

    Clayton, Dale H.

    Cellular Biology at the University of Utah The Department of Biology at the University of Utah invites applications for a tenure- track faculty position at the assistant professor level in cellular biology. Applicants should be addressing fundamental questions in any aspect of eukaryotic cellular

  2. Cellular Tracking in Time-lapse Phase Contrast Images K. Thirusittampalam, M.J. Hossain, O. Ghita, and P.F. Whelan

    E-Print Network [OSTI]

    Whelan, Paul F.

    Cellular Tracking in Time-lapse Phase Contrast Images K. Thirusittampalam, M.J. Hossain, O. Ghita {kethesan, julius, ghitao, whelanp}@eeng.dcu.ie Abstract The quantitative analysis of live cellular structures in time-lapse image sequences is a key issue in evaluating biological processes such as cellular

  3. Surface Science Reports 61 (2006) 429444 www.elsevier.com/locate/surfrep

    E-Print Network [OSTI]

    2006-01-01

    bilayers: From biophysical studies to sensor design Edward T. Castellana, Paul S. Cremer Department, but also hosts much of the machinery for cellular communication and transport across the cell membrane

  4. Multi-canister overpack closure operations location study

    SciTech Connect (OSTI)

    Goldmann, L.H.

    1996-04-15

    The Spent Nuclear Fuel Path Forward Project (SNF Project) has been established to develop engineered methods for the expedited removal of the irradiated uranium fuel from the K East (KE) and K West (KW) Basins. As specified by the SNF Project, the SNF will be removed from the K Basins, conditioned for dry storage and placed in a long term interim storage facility located in the 200 East Area. The SNF primarily consists of Zircaloy-2 clad uranium fuel discharged from the N-Reactor. A small portion of the SNF is Single Pass Reactor (SPR) Fuel, which is aluminum clad uranium fuel. The SNF will be loaded into Multi-Canister Overpacks (MCOs) at the K Basins, transferred to the Cold Vacuum Drying (CVD) facility for initial fuel conditioning, and transported to the Canister Storage Building (CSB) for staging, final fuel conditioning, and dry storage. The MCO is a transportation, conditioning, and storage vessel. The MCO consists of a 24 inch pipe with a welded bottom closure and a top closure that is field welded after the MCO is loaded with SNF. The MCO is handled and transported in the vertical orientation during all operations. Except for operations within the CSB, the MCO is always within the transportation cask which primarily provides radiological shielding and structural protection of the MCO. The MCO closure operations location study provides a relative evaluation of location options at the K Basins and the CVD Facility and recommends that the MCO closure weld be performed, inspected, and repaired at the CVD Facility.

  5. Collection of liquid from below-ground location

    DOE Patents [OSTI]

    Phillips, Steven J. (Kennewick, WA); Alexander, Robert G. (Kennewick, WA)

    1995-01-01

    A method of retrieving liquid from a below-ground collection area by permitting gravity flow of the liquid from the collection area to a first closed container; monitoring the level of the liquid in the closed container; and after the liquid reaches a given level in the first closed container, transferring the liquid to a second closed container disposed at a location above the first closed container, via a conduit, by introducing into the first closed container a gas which is substantially chemically inert with respect to the liquid, the gas being at a pressure sufficient to propel the liquid from the first closed container to the second closed container.

  6. An estimate for the location of QCD critical end point

    E-Print Network [OSTI]

    Roy A. Lacey; N. N. Ajitanand; J. M. Alexander; P. Chung; J. Jia; A. Taranenko; P. Danielewicz

    2008-05-09

    It is proposed that a study of the ratio of shear viscosity to entropy density $\\frac{\\eta}{s}$ as a function of the baryon chemical potential $\\mu_B$, and temperature T, provides a dynamic probe for the critical end point (CEP) in hot and dense QCD matter. An initial estimate from an elliptic flow excitation function gives $\\mu^{\\text{cep}}_B \\sim 150-180$ MeV and $T_{\\text{cep}} \\sim 165 - 170$ MeV for the location of the the CEP. These values place the CEP in the range for "immediate" validation at RHIC.

  7. Locations of criticality alarms and nuclear accident dosimeters at Hanford

    SciTech Connect (OSTI)

    Not Available

    1992-08-01

    Hanford facilities that contain fissionable materials capable of achieving critical mass are monitored with nuclear accident dosimeters (NADS) in compliance with the requirements of DOE Order 5480.11, Chapter XI, Section 4.c. (DOE 1988). The US Department of Energy (DOE) Richland Field Office (RL) has assigned the responsibility for maintaining and evaluating the Hanford NAD system to the Instrumentation and External Dosimetry (I ED) Section of Pacific Northwest Laboratory's (PNL's) Health Physics Department. This manual provides a description of the Hanford NAD, criteria and instructions for proper NAD placement, and the locations of these dosimeters onsite.

  8. Microfluidic ultrasonic particle separators with engineered node locations and geometries

    DOE Patents [OSTI]

    Rose, Klint A; Fisher, Karl A; Wajda, Douglas A; Mariella, Jr., Raymond P; Bailey, Christoppher; Dehlinger, Dietrich; Shusteff, Maxim; Jung, Byoungsok; Ness, Kevin D

    2014-05-20

    An ultrasonic microfluidic system includes a separation channel for conveying a sample fluid containing small particles and large particles, flowing substantially parallel, adjacent to a recovery fluid, with which it is in contact. An acoustic transducer produces an ultrasound standing wave, that generates a pressure field having at least one node of minimum pressure amplitude. An acoustic extension structure is located proximate to said separation channel for positioning said acoustic node off center in said acoustic area and concentrating the large particles in said recovery fluid stream.

  9. Sandia National Laboratories: Locations: Albuquerque, New Mexico: Life in

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home RoomPreservation ofAlbuquerque Albuquerque Housing Education Recreation Locations Life in

  10. Sandia National Laboratories: Locations: Albuquerque, New Mexico: Visiting

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home RoomPreservation ofAlbuquerque Albuquerque Housing Education Recreation Locations Life

  11. Sandia National Laboratories: Locations: Livermore, California: Life in

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home RoomPreservation ofAlbuquerque Albuquerque Housing Education Recreation Locations

  12. Location | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverseIMPACTThousand CubicResourcelogo and-E CChinaC L S C OLocalTissue andLocation

  13. 9.013J / 7.68J Cellular and Molecular Neurobiology: The Brain and Cognitive Sciences III, Spring 2003

    E-Print Network [OSTI]

    Constantine-Paton, Martha, 1947-

    Subject covers all major areas of cellular and molecular neurobiology including excitable cells and membranes, ion channels and receptors, synaptic transmission, cell type determination, axon guidance and targeting, neuronal ...

  14. The use of a simple cellular automata model as a testbed for kinetic theories of vehicular traffic flow 

    E-Print Network [OSTI]

    Raney, Bryan Keith

    2000-01-01

    The broad objective of this thesis is to explore the potential for the use of Cellular Automata (CA) models to provide a testbed for comparison of different kinetic models of vehicular traffic. We intend to develop a quantitative technique...

  15. Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase

    E-Print Network [OSTI]

    Buganim, Yosef

    During cellular reprogramming, only a small fraction of cells become induced pluripotent stem cells (iPSCs). Previous analyses of gene expression during reprogramming were based on populations of cells, impeding single-cell ...

  16. A Hybrid Geometric Modeling Method for Large Scale Conformal Cellular 3D Systems, 26081 Avenue Hall, Valencia, CA 91354

    E-Print Network [OSTI]

    Chen, Yong

    Structures, Conformal Structures, Additive Manufacturing, STL 1 INTRODUCTION Cellular material structures can distributions than stochastic metal foams [5]. With the development of additive manufacturing processes (also, 8, 9]. The manufacturing of mesoscopic truss structures utilizes the unique capability of additive

  17. Modules M.Sc. Biochemistry and Molecular Biology Title of the module Cell physiology of marine organisms: cellular energy budget

    E-Print Network [OSTI]

    Diekmann, Martin

    Cell physiology of marine organisms: cellular energy budget and metabolic fingerprinting Term of environmental factors such as temperature on cell metabolism of marine ectothermal organisms - Conceptual Deepening the knowledge of cell physiology of marine ectotherms. Topics will be: - Environmental impact

  18. Location standards for RCRA Treatment, Storage, and Disposal Facilities (TSDFs). RCRA Information Brief

    SciTech Connect (OSTI)

    Not Available

    1993-10-01

    This bulletin describes RCRA location standards for hazardous waste storage and disposal facilities.

  19. Arousal-enhanced location memory for pictures q Mara Mather *, Kathryn Nesmith

    E-Print Network [OSTI]

    Mather, Mara

    Arousal-enhanced location memory for pictures q Mara Mather *, Kathryn Nesmith Social Sciences 2-enhanced location memory for pictures. After an incidental encoding task, par- ticipants were more likely to remember the locations of positive and negative arousing pictures than the locations of non

  20. Collection of liquid from below-ground location

    DOE Patents [OSTI]

    Phillips, S.J.; Alexander, R.G.

    1995-05-30

    A method is described for retrieving liquid from a below-ground collection area by permitting gravity flow of the liquid from the collection area to a first closed container; monitoring the level of the liquid in the closed container; and after the liquid reaches a given level in the first closed container, transferring the liquid to a second closed container disposed at a location above the first closed container, via a conduit, by introducing into the first closed container a gas which is substantially chemically inert with respect to the liquid, the gas being at a pressure sufficient to propel the liquid from the first closed container to the second closed container. 3 figs.