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Sample records for latvia gv guinea

  1. GV DTit

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    £c £iV£d GV DTit «0- i3?0 ■ Comparison of 3D Classical Trajectory and Transition-State Theory Reaction Cross Sections t . ' G. W. Koeppl and M. Karplus Department of Chemistry, Harvard University Cambridge, Massachusetts 02138 -------------------------- L E G A L N O T I C E --------------------------- T h is r e p o r t was p re p a re d as an a c c o u n t o f w o rk sp onsored b y th e U n ite d S tates G o v e rn m e n t. N e ith e r th e U n ite d States n o r th e U n ite d S tates A

  2. Latvia: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    Country Profile Name Latvia Population 2,070,371 GDP 34,118,000,000 Energy Consumption 0.16 Quadrillion Btu 2-letter ISO code LV 3-letter ISO code LVA Numeric ISO...

  3. Deputy Secretary of Energy Meets with President of Latvia | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Deputy Secretary of Energy Daniel Poneman meets with President Zatlers of Latvia | DOE photo: Ken Shipp April Saylor April Saylor Former Digital Outreach Strategist, Office of ...

  4. Constraining the disk masses of the class I binary protostar GV Tau

    SciTech Connect (OSTI)

    Sheehan, Patrick D.; Eisner, Josh A.

    2014-08-10

    We present new spatially resolved 1.3 mm imaging with CARMA of the GV Tau system. GV Tau is a Class I binary protostar system in the Taurus Molecular Cloud, the components of which are separated by 1.''2. Each protostar is surrounded by a protoplanetary disk, and the pair may be surrounded by a circumbinary envelope. We analyze the data using detailed radiative transfer modeling of the system. We create synthetic protostar model spectra, images, and visibilities and compare them with CARMA 1.3 mm visibilities, a Hubble Space Telescope near-infrared scattered light image, and broadband spectral energy distributions from the literature to study the disk masses and geometries of the GV Tau disks. We show that the protoplanetary disks around GV Tau fall near the lower end of estimates of the Minimum Mass Solar Nebula, and may have just enough mass to form giant planets. When added to the sample of Class I protostars from Eisner, we confirm that Class I protostars are on average more massive than their Class II counterparts. This suggests that substantial dust grain processing occurs between the Class I and Class II stages, and may help to explain why the Class II protostars do not appear to have, on average, enough mass in their disks to form giant planets.

  5. ,"U.S. Liquefied Natural Gas Imports From Equatorial Guinea ...

    U.S. Energy Information Administration (EIA) Indexed Site

    Equatorial Guinea (MMcf)" ,"Click worksheet name or tab at bottom for data" ,"Worksheet ... Natural Gas Imports From Equatorial Guinea (MMcf)",1,"Monthly","122015" ,"Release ...

  6. Guinea: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    Country Profile Name Guinea Population 10,628,972 GDP 5,212,000,000 Energy Consumption 0.02 Quadrillion Btu 2-letter ISO code GN 3-letter ISO code GIN Numeric ISO...

  7. Papua New Guinea Improved Energy Access for Rural Communities...

    Open Energy Info (EERE)

    Communities Location of project Papua New Guinea Energy Services Lighting, Cooking and water heating, Space heating, Cooling, Information and communications, Earning a living...

  8. Guinea-USAID Climate Activities | Open Energy Information

    Open Energy Info (EERE)

    International Development Sector Energy, Land Focus Area Renewable Energy, Forestry, Agriculture Topics Background analysis Website http:www.usaid.govourwork Country Guinea...

  9. Papua New Guinea Geothermal Region | Open Energy Information

    Open Energy Info (EERE)

    ENERGYGeothermal Home Papua New Guinea Geothermal Region Details Areas (1) Power Plants (1) Projects (0) Techniques (0) References Geothermal Region Data Area USGS Resource...

  10. On the origin of a kink in the hardness spectra of cosmic-ray protons and helium nuclei in the vicinity of 230 GV

    SciTech Connect (OSTI)

    Loznikov, V. M. Erokhin, N. S. Zol’nikova, N. N.; Mikhailovskaya, L. A.

    2015-08-15

    A three-component phenomenological model for the description of specific features of spectra of cosmic-ray protons and helium nuclei in the hardness range from 30 to 2 × 10{sup 5} GV is proposed. The first component corresponds to the constant background; the second component, to a variable “soft” (30–500 GV) heliospheric source; and the third component, to a variable “hard” (0.5–200 TV) galactic source inside a local bubble. The corresponding “surfatron accelerators” are responsible for the existence and variability of both sources. In order for such accelerators to operate, there should be an extended area with a nearly uniform and constant (in both the magnitude and direction) magnetic field and electromagnetic waves propagating perpendicular (or obliquely) to it. The dimensions of each source determine the maximum energy to which cosmic rays can be accelerated. The soft source with a size of ∼100 au lies at the periphery of the heliosphere, beyond the terminal shock, while the hard source with a size of >0.1 pc is located near the boundary of a local interstellar cloud at a distance of ∼0.01 pc from the Sun. A kink in the hardness spectra of p and He (near the hardness of about 230 GV) is caused by the variability of physical conditions in the acceleration region and depends on the relation between the amplitudes and power-law indices of the background, the soft heliospheric source, and the nearby hard galactic source. Ultrarelativistic acceleration of p and He in space plasma by an electromagnetic wave propagating perpendicular to the external magnetic field is investigated using numerical calculations. The conditions for particle trapping by the wave, as well as the dynamics of the velocity and momentum components, are analyzed. The calculations show that, in contrast to electrons and positrons (e{sup +}), a trapped proton can escape from the effective potential well after a relatively short time, thereby terminating to accelerate. Such an effect gives rise to softer spectra of p and He sources as compared to those of e{sup +}. The possibility of deviation of the spectra of accelerated protons from standard power-law dependences due to the surfatron mechanism is discussed.

  11. Guinea-Bissau: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    Country Profile Name Guinea-Bissau Population 1,345,479 GDP 870,000,000 Energy Consumption 0.01 Quadrillion Btu 2-letter ISO code GW 3-letter ISO code GNB Numeric ISO...

  12. A Pilot Study of Uterine Artery Embolization with Tris-Acryl Gelatin Microspheres in Guinea Pigs

    SciTech Connect (OSTI)

    Zhuang Wenquan; Tan Guosheng; Guo Wenbo, E-mail: patrickguo2008@163.com [The First Affiliated Hospital of Sun Yat-sen University, Department of Interventional Radiology (China); Yang Jianyong [The First Affiliated Hospital of Sun Yat-sen University, Department of Radiology (China)

    2012-06-15

    Objective: This study was designed to establish guinea pigs as an animal model for uterine artery embolization (UAE) with tris-acryl gelatin microspheres (TAGM). Methods: Twenty-five female adult guinea pigs were randomly divided into two groups, including a uterine artery casting mould group (n = 10) and a UAE group (n = 15). Pelvic angiography and vascular casting mould were performed in the first group. The anatomical characters of the pelvic cavity in guinea pigs were described. In the second group, the technical feasibility of performing UAE with TAGM in guinea pigs was investigated. The histopathological slides of the uterus of guinea pigs after UAE were examined to inspect the outcomes of UAE. Results: The uterine artery springs from the internal iliac artery, ascends tortuously along the cervix, and gives off vertically 8-10 branches to the cervix uteri and uterine horns. The diameters of the trunk of the uterine artery and its first branch were 0.32 {+-} 0.027 mm and 0.14 {+-} 0.01 mm, respectively. For UAE animals, the dosages of 40-120 and 100-300 {mu}m TAGM were 0.033 {+-} 0.003 ml and 0.015 {+-} 0.002 ml, respectively. On histopathological slides, embosphere particles were found in the first branches of the uterine artery, the subserous arteries, and the intramural arteries. Inflammatory reactions in the uterus were common in guinea pigs after UAE. Local or dispersed areas of necrosis in uterus also were observed in a few guinea pigs. Conclusions: Guinea pigs are an appropriate and feasible model for UAE with TAGM.

  13. Sources and management of hazardous waste in Papua New Guinea

    SciTech Connect (OSTI)

    Singh, K.

    1996-12-31

    Papua New Guinea (PNG) has considerable mineral wealth, especially in gold and copper. Large-scale mining takes place, and these activities are the source of most of PNG`s hazardous waste. Most people live in small farming communities throughout the region. Those living adjacent to mining areas have experienced some negative impacts from river ecosystem damage and erosion of their lands. Industry is centered mainly in urban areas and Generates waste composed of various products. Agricultural products, pesticide residues, and chemicals used for preserving timber and other forestry products also produce hazardous waste. Most municipal waste comes from domestic and commercial premises; it consists mainly of combustibles, noncombustibles, and other wastes. Hospitals generate pathogenic organisms, radioactive materials, and chemical and pharmaceutical laboratory waste. Little is known about the actual treatment of waste before disposal in PNG. Traditional low-cost waste disposal methods are usually practiced, such as use of landfills; storage in surface impoundments; and disposal in public sewers, rivers, and the sea. Indiscriminate burning of domestic waste in backyards is also commonly practiced in urban and rural areas. 10 refs., 4 tabs.

  14. Protein A suppresses immune responses during Staphylococcus aureus bloodstream infection in guinea pigs

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Kim, Hwan Keun; Falugi, Fabiana; Thomer, Lena; Missiakas, Dominique M.; Schneewind, Olaf

    2015-01-06

    Staphylococcus aureus infection is not associated with the development of protective immunity, and disease relapses occur frequently. We hypothesize that protein A, a factor that binds immunoglobulin Fcγ and cross-links VH3 clan B cell receptors (IgM), is the staphylococcal determinant for host immune suppression. To test this, vertebrate IgM was examined for protein A cross-linking. High VH3 binding activity occurred with human and guinea immunoglobulin, whereas mouse and rabbit immunoglobulins displayed little and no binding, respectively. Establishing a guinea pig model of S. aureus bloodstream infection, we show that protein A functions as a virulence determinant and suppresses host Bmore » cell responses. Immunization with SpAKKAA, which cannot bind immunoglobulin, elicits neutralizing antibodies that enable guinea pigs to develop protective immunity.« less

  15. Price of Elba Island, GA Natural Gas LNG Imports from Equatorial Guinea

    U.S. Energy Information Administration (EIA) Indexed Site

    (Dollars per Thousand Cubic Feet) Equatorial Guinea (Dollars per Thousand Cubic Feet) Price of Elba Island, GA Natural Gas LNG Imports from Equatorial Guinea (Dollars per Thousand Cubic Feet) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 2000's -- 6.11 -- -- 2010's -- - = No Data Reported; -- = Not Applicable; NA = Not Available; W = Withheld to avoid disclosure of individual company data. Release Date: 4/29/2016 Next Release Date: 5/31/2016 Referring Pages:

  16. Lake Charles, LA Natural Gas LNG Imports from Equatorial Guinea (Dollars

    U.S. Energy Information Administration (EIA) Indexed Site

    per Thousand Cubic Feet) Lake Charles, LA Natural Gas LNG Imports from Equatorial Guinea (Dollars per Thousand Cubic Feet) Lake Charles, LA Natural Gas LNG Imports from Equatorial Guinea (Dollars per Thousand Cubic Feet) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 2000's -- 6.75 -- -- 2010's -- - = No Data Reported; -- = Not Applicable; NA = Not Available; W = Withheld to avoid disclosure of individual company data. Release Date: 4/29/2016 Next Release Date:

  17. Biomass resource potential for selected crops in Hawaii. [Koa haole (giant leucaena); napier and guinea grass

    SciTech Connect (OSTI)

    Seki, A.

    1982-06-01

    The biomass crops selected for review were koa haole (giant leucaena), napier and guinea grass, and eucalyptus (saligna, grandis, and globulus). The islands examined were Hawaii, Kauai, Maui, and Molokai. The potential land acreage for growing these crops was estimated grossly. As anticipated, the island of Hawaii had the largest land potential with eucalyptus having the greatest potential land acreage.

  18. Protein A suppresses immune responses during Staphylococcus aureus bloodstream infection in guinea pigs

    SciTech Connect (OSTI)

    Kim, Hwan Keun; Falugi, Fabiana; Thomer, Lena; Missiakas, Dominique M.; Schneewind, Olaf

    2015-01-06

    Staphylococcus aureus infection is not associated with the development of protective immunity, and disease relapses occur frequently. We hypothesize that protein A, a factor that binds immunoglobulin Fcγ and cross-links VH3 clan B cell receptors (IgM), is the staphylococcal determinant for host immune suppression. To test this, vertebrate IgM was examined for protein A cross-linking. High VH3 binding activity occurred with human and guinea immunoglobulin, whereas mouse and rabbit immunoglobulins displayed little and no binding, respectively. Establishing a guinea pig model of S. aureus bloodstream infection, we show that protein A functions as a virulence determinant and suppresses host B cell responses. Immunization with SpAKKAA, which cannot bind immunoglobulin, elicits neutralizing antibodies that enable guinea pigs to develop protective immunity.

  19. Impacts of dependent development on community and resources in Kilenge, Papua New Guinea

    SciTech Connect (OSTI)

    Grant, J.

    1987-06-01

    In recent years, many rural Third World communities have suffered from the gradual degradation of the natural resources on which they depend. The Kilenge of the West New Britain, Papua New Guinea, offer such an example. The paper examines some of the nutritional, economic, social, and political impacts of these changes on the individual, on the household, and on the community in one Kilenge village. It argues that there may be alternatives to dependent development for this community. It concludes that redirected priorities can assist indigenous communities like Kilenge to achieve sustainable self-directed economic improvement.

  20. In vitro effects of fatty acids on goat, calf and guinea pig hepatic gluconeogenesis

    SciTech Connect (OSTI)

    Aiello, R.J.; Armentano, L.E.

    1986-03-05

    Isolated hepatocytes from male guinea pigs, ruminating goats and bull calves were incubated at 39 C for 1h. Fatty acids C18:1, C16, and C8 (.5, 1, 2 mM) were added as albumin complexes (3:1 molar ratio), C2 and C4 (1.25, 2.5 and 5 mM) were added as Na salts. In ruminant cells C2 had no effect on (2-/sup 14/C)-propionate (PROP) (2.5 mM) or (U-/sup 14/C)-L-lactate (LACT) (2.5 mM) metabolism. C4 (2.5 or 5 mM) decreased (/sup 14/C)-glucose (GLU) (P < .01) from PROP (48% goats, 68% calves) and decreased LACT conversion to GLU, (27% goats, 50% calves), C8, C16 and C18:1 effects depended on gluconeogenic substrate and species. In goat cells conversion of PROP to GLU was increased (P < .01) by C18:1 (30%) and C8 (52%) with C16 showing a similar trend. There were no interactions between the effects of fatty acids and lactation state (lactating does vs wethers). In goat cells C8 increased PROP conversion to GLU relative to oxidation, other fatty acids did not change relative rates. In calf cells C18:1, C16 and C8 had no effect on PROP metabolism. C8 inhibited gluconeogenesis from LACT in goats (24%) (P < .07) and calves (47%) (P < .01). In contrast fatty acids decreased (P < .01) GLU production from PROP (C18:1 90%, C8 80%) and LACT (C18:1 75%, C8 75%) in cells from guinea pigs. They have established a clear difference in the regulation of gluconeogenesis among species which contain similar intracellular distribution of P-enolpyruvate carboxykinase.

  1. Estimation of neutrophil infiltration into hairless guinea pig skin treated with 2,2' -dichlorodiethyl sulfide

    SciTech Connect (OSTI)

    Bongiovanni, R.; Millard, C.B.; Schulz, S.M.; Romano, J.M.

    1993-05-13

    Despite growing acceptance of the hairless guinea pig (HPG) for evaluating sulfur mustard (2,2'dichlorodiethylsulfide, HD) skin injury, there are presently few antivesicant drug assessment endpoints validated in vivo for this model. We measured the activity of myeloperoxidase (MPO) to characterize the dose- and time-dependence of polymorphonuclear leukocyte (PMN) infiltration during development of the HD lesion. Biopsies were obtained from the dorsal thoracic-lumbar area of HGPs at successive 3 hr time intervals for up to 24 hrs following controlled exposure to either 5, 7, 8 or 10 min HD vapor. The presence of PMNs, as judged by MPO levels, peaked at 9 hrs irrespective of total HD vapor dose. The maximum response was a 20-fold increase compared to unexposed control sites at 9 hrs following 10 min HD vapor. This time period coincides with epidermal detachment characterized previously by electron microscopy in the HGP. By 24 hrs post-exposure, the MPO levels subsided markedly (2-fold compared to controls). These results suggest that PMNs participate in the HGP cutaneous inflammatory response following exposure to HD and that MPO may be a useful biological marker for evaluating putative antivesicants.

  2. GV1 Solar Power Plant | Open Energy Information

    Open Energy Info (EERE)

    EFAULT","autoinfowindows":false,"kml":,"gkml":,"fusiontables":,"resizable":false,"tilt":0,"kmlrezoom":false,"poi":true,"imageoverlays":,"markercluster":false,"searchmarkers...

  3. Mast cells in citric acid-induced cough of guinea pigs

    SciTech Connect (OSTI)

    Lai, Y.-L. . E-mail: tiger@ha.mc.ntu.edu.tw; Lin, T.-Y.

    2005-01-01

    It was demonstrated previously that mast cells play an important role in citric acid (CA)-induced airway constriction. To investigate the role of mast cells in CA-induced cough, three experiments were carried out in this study. In the first experiment, 59 guinea pigs were employed and we used compound 48/80 to deplete mast cells, cromolyn sodium to stabilize mast cells, MK-886 to inhibit leukotriene synthesis, pyrilamine to antagonize histamine H{sub 1} receptor, methysergide to antagonize serotonin receptor, and indomethacin to inhibit cyclooxygenase. In the second experiment, 56 compound 48/80-pretreated animals were divided into two parts; the first one was used to test the role of exogenous leukotriene (LT) C{sub 4}, while the second one to test the role of exogenous histamine in CA-induced cough. Each animal with one of the above pretreatments was exposed sequentially to saline (baseline) and CA (0.6 M) aerosol, each for 3 min. Then, cough was recorded for 12 min using a barometric body plethysmograph. In the third experiment, the activation of mast cells upon CA inhalation was investigated by determining arterial plasma histamine concentration in 17 animals. Exposure to CA induced a marked increase in cough number. Compound 48/80, cromolyn sodium, MK-886 and pyrilamine, but not indomethacin or methysergide, significantly attenuated CA-induced cough. Injection of LTC{sub 4} or histamine caused a significant increase in CA-induced cough in compound 48/80-pretreated animals. In addition, CA inhalation caused significant increase in plasma histamine concentration, which was blocked by compound 48/80 pretreatment. These results suggest that mast cells play an important role in CA aerosol inhalation-induced cough via perhaps mediators LTs and histamine.

  4. Reduction of erythema in hairless guinea pigs after cutaneous sulfur mustard vapor exposure by pretreatment with niacinamide, promethazine and indomethacin

    SciTech Connect (OSTI)

    Yourick, J.J.; Dawson, J.S.; Mitcheltree, L.W.

    1995-12-31

    Erythema is the initial symptom that occurs after sulfur mustard (HD) cutaneous exposure. The time course of HD-induced erythema is similar to that observed after UV irradiation, which can be reduced by indomethacin. Sulfur mustard lethality is decreased by using promethazine, which is an antihistamine. Niacinamide can reduce microvesication after HD vapor exposure in hairless guinea pig (HGP) skin. The present study examines the effect of the combined administration of niacinamide, indomethacin and promethazine used alone or in all possible combinations on the degree of erythema and histopathologic skin damage after HD exposure in HGP. Niacinamide (750 mg kg%`, i.p.), promethazine (12.5 mg kg%1, i.m.) or indomethacin (4 mg kg%1, p.o.) used singly or in combination was given as a 30-min pretreatment before an 8-min HD vapor cup skin exposure. Using a combination pretreatment of niacinamide, promethazine and indomethacin, erythema was reduced at 4 (91%) and 6 (55%) h, but not 24 h after HD. The incidence of histopathological skin changes (microvesicles, follicular involvement, epidermal necrosis, intracellular edema and pustular epidermatitis) 24 h after HD was not reduced. This study indicates that HD (induced erythema) may result from several different mechanisms, including inflammation, histamine release and DNA damage. It is suggested that two phases of inflammation may occur: an early phase sensitive to antihistamines and non-steroidal antiinflammatory drugs and a late phase of extensive cell damage that was not sensitive to these drug pretreatments.

  5. Cutaneous uptake of 14C-HD vapor by the hairless guinea pig. Technical report, December 1992-June 1993

    SciTech Connect (OSTI)

    Logan, T.P.; Bongiovanni, R.; Millard, C.B.; Shutz, M.B.; Schultz, S.M.

    1996-10-01

    The hairless guinea pig (HGP) is used by our laboratory to model the human cutaneous response to sulfur mustard (HD) exposure. We have determined the HD content in the skin of HOP after 7-minute exposures to vapors saturated with a mixture of HD and 14C-HD. Concentration/time (C1) values in the range of 2 mg/sq cm/min were determined by counting skin 14C disintegrations per minute (dpm) in animals euthanized immediately after exposure. These values are similar to human penetration rates obtained by other investigators. A direct relationship between C1 and relative humidity was demonstrated in 5 of 6 studies. A rate curve monitoring the reduction in skin 14C dpm was developed for animals euthanized between 0 and 24 hours post exposure. This curve showed the greatest change after 1 hour. Epidermal and dermal distribution of 14C at 24 hours was measured for two animals. Site preference for HD penetration, multiple use of a vapor cap containing HD, and 14C content of adhesive tape were also investigated with radiolabeled HD to evaluate other aspects of the experimental model. These results contribute to a better understanding of the cutaneous response to HD in the HGP model.

  6. EUDEEP (Smart Grid Project) (Latvia) | Open Energy Information

    Open Energy Info (EERE)

    technical and nontechnical barriers that prevent a massive deployment of distributed energy resources (DER) in Europe. In partnership with manufacturers, research organizations,...

  7. Ascorbic acid suppresses endotoxemia and NF-κB signaling cascade in alcoholic liver fibrosis in guinea pigs: A mechanistic approach

    SciTech Connect (OSTI)

    Abhilash, P.A.; Harikrishnan, R.; Indira, M.

    2014-01-15

    Alcohol consumption increases the small intestinal bacterial overgrowth (SIBO) and intestinal permeability of endotoxin. The endotoxin mediated inflammatory signaling plays a major role in alcoholic liver fibrosis. We evaluated the effect of ascorbic acid (AA), silymarin and alcohol abstention on the alcohol induced endotoxemia and NF-κB activation cascade pathway in guinea pigs (Cavia porcellus). Guinea pigs were administered ethanol at a daily dose of 4 g/kg b.wt for 90 days. After 90 days, ethanol administration was stopped. The ethanol treated animals were divided into abstention, silymarin (250 mg/kg b.wt) and AA (250 mg/kg b.wt) supplemented groups and maintained for 30 days. The SIBO, intestinal permeability and endotoxin were significantly increased in the ethanol group. The mRNA expressions of intestinal proteins claudin, occludin and zona occludens-1 were significantly decreased in ethanol group. The mRNA levels of inflammatory receptors, activity of IKKβ and the protein expressions of phospho-IκBα, NF-κB, TNF-α, TGF-β{sub 1} and IL-6 were also altered in ethanol group. The expressions of fibrosis markers α-SMA, α{sub 1} (I) collagen and sirius red staining in the liver revealed the induction of fibrosis. But the supplementation of AA could induce greater reduction of ethanol induced SIBO, intestinal barrier defects, NF-κB activation and liver fibrosis than silymarin. The possible mechanism may be the inhibitory effect of AA on SIBO, intestinal barrier defect and IKKβ, which decreased the activation of NF-κB and synthesis of cytokines. This might have led to suppression of HSCs activation and liver fibrosis. - Highlights: • Alcohol increases intestinal bacterial overgrowth and permeability of endotoxin. • Endotoxin mediated inflammation plays a major role in alcoholic liver fibrosis. • Ascorbic acid reduces endotoxemia, NF-κB activation and proinflammatory cytokines. • AA's action is by inhibition of SIBO, IKKβ and alteration of intestinal permeability. • This might have led to suppression of HSCs activation and liver fibrosis.

  8. A comprehensive evaluation of the efficacy of leading oxime therapies in guinea pigs exposed to organophosphorus chemical warfare agents or pesticides

    SciTech Connect (OSTI)

    Wilhelm, Christina M.; Snider, Thomas H.; Babin, Michael C.; Jett, David A.

    2014-12-15

    The currently fielded pre-hospital therapeutic regimen for the treatment of organophosphorus (OP) poisoning in the United States (U.S.) is the administration of atropine in combination with an oxime antidote (2-PAM Cl) to reactivate inhibited acetylcholinesterase (AChE). Depending on clinical symptoms, an anticonvulsant, e.g., diazepam, may also be administered. Unfortunately, 2-PAM Cl does not offer sufficient protection across the range of OP threat agents, and there is some question as to whether it is the most effective oxime compound available. The objective of the present study is to identify an oxime antidote, under standardized and comparable conditions, that offers protection at the FDA approved human equivalent dose (HED) of 2-PAM Cl against tabun (GA), sarin (GB), soman (GD), cyclosarin (GF), and VX, and the pesticides paraoxon, chlorpyrifos oxon, and phorate oxon. Male Hartley guinea pigs were subcutaneously challenged with a lethal level of OP and treated at approximately 1 min post challenge with atropine followed by equimolar oxime therapy (2-PAM Cl, HI-6 DMS, obidoxime Cl{sub 2}, TMB-4, MMB4-DMS, HLö-7 DMS, MINA, and RS194B) or therapeutic-index (TI) level therapy (HI-6 DMS, MMB4-DMS, MINA, and RS194B). Clinical signs of toxicity were observed for 24 h post challenge and blood cholinesterase [AChE and butyrylcholinesterase (BChE)] activity was analyzed utilizing a modified Ellman's method. When the oxime is standardized against the HED of 2-PAM Cl for guinea pigs, the evidence from clinical observations, lethality, quality of life (QOL) scores, and cholinesterase reactivation rates across all OPs indicated that MMB4 DMS and HLö-7 DMS were the two most consistently efficacious oximes. - Highlights: • First comprehensive evaluation of leading AChE oxime reactivators • All oximes are compared against current U.S. therapy 2-PAM Cl. • Relative therapeutic oxime efficacies against OP CWNA and pesticides • Contribution to more effective antidotes for civilian and military populations.

  9. Equatorial Guinea: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    by building new gas-fired power stations and investing in the construction of new dams.Work is ongoing on the Djibloho hydroelectric plant project on the Wele River near...

  10. U.S. LNG Imports from Equatorial Guinea

    U.S. Energy Information Administration (EIA) Indexed Site

    7-2016 Liquefied Natural Gas Prices -- -- -- -- -- -- 2007

  11. Papua New Guinea-Pilot Program for Climate Resilience (PPCR)...

    Open Energy Info (EERE)

    Development (IISD) Sector Climate, Energy, Land, Water Focus Area Renewable Energy, Agriculture, Biomass, - Waste to Energy, Economic Development, Forestry, Greenhouse...

  12. Papua New Guinea-Lowering Emissions in Asia's Forests (LEAF)...

    Open Energy Info (EERE)

    assessing, improving, and implementing REDD+- related forest policies; improving forest management; and encouraging equitable sharing of REDD+ benefits. The program will tailor...

  13. Papua New Guinea: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    EIA Natural Gas Reserves 226,500,000,000 Cubic Meters (cu m) 44 2010 CIA World Factbook Oil Reserves 170,000,000 Barrels (bbl) 62 2010 CIA World Factbook Energy Maps featuring...

  14. Papua New Guinea-Low Emissions Asian Development (LEAD) Program...

    Open Energy Info (EERE)

    the growth of greenhouse gas emissions. The LEAD program supports and enhances country-led development programs, plans, and policies, and complements efforts of other...

  15. Guinea-Bissau: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    0 Area(km) Class 3-7 Wind at 50m 116 1990 NREL Solar Potential 93,662,158 MWhyear 132 2008 NREL Coal Reserves Unavailable Million Short Tons NA 2008 EIA Natural Gas...

  16. USAID Europe and Eurasia Climate Program | Open Energy Information

    Open Energy Info (EERE)

    Country Armenia, Republic of Macedonia, Russia, Ukraine, Poland, Kazakhstan, Hungary, Turkey, Uzbekistan, Turkmenistan, Lithuania, Estonia, Latvia, Azerbaijan, Tajikistan Western...

  17. USAID West Africa Climate Program | Open Energy Information

    Open Energy Info (EERE)

    Guinea, Guinea-Bissau, Cameroon, Gabon, Equatorial Guinea, Chad, Sao Tome and Principe, Cape Verde Western Africa, Western Africa, Western Africa, Western Africa, Western...

  18. Price of U.S. Liquefied Natural Gas Imports From Equatorial Guinea (Dollars

    U.S. Energy Information Administration (EIA) Indexed Site

    per Thousand Cubic Feet) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 2000's 6.32 -- -- 2010's -- -- -- --

  19. U.S. Liquefied Natural Gas Imports From Equatorial Guinea (Million Cubic

    U.S. Energy Information Administration (EIA) Indexed Site

    Feet) Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 2000's 17,795 0 0 2010's 0 0 0 0

  20. Price of U.S. Liquefied Natural Gas Imports From Equatorial Guinea (Dollars

    U.S. Energy Information Administration (EIA) Indexed Site

    per Thousand Cubic Feet) Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2007 -- -- -- -- -- 7.46 6.04 6.18 -- -- -- -- 2008 -- -- -- -- -- -- -- -- -- -- -- -- 2009 -- -- -- -- -- -- -- -- -- -- -- -- 2010 -- -- -- -- -- -- -- -- -- -- -- -- 2011 -- -- -- -- -- -- -- -- -- -- -- -- 2012 -- -- -- -- -- -- -- -- -- -- -- -- 2013 -- -- -- -- -- -- -- -- -- -- -- -- 2014 -- -- -- -- -- -- -- -- -- -- -- -- 2015 -- -- -- -- -- -- -- -- -- -- -- -- 2016

  1. U.S. Liquefied Natural Gas Imports From Equatorial Guinea (Million...

    U.S. Energy Information Administration (EIA) Indexed Site

    Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2007 0 0 0 0 0 2,910 8,989 5,896 0 0 0 0 2008 0 0 0 0 0 0 0 0 0 0 0 0 2009 0 0 0 0 0 0 0 0 0 0 0 0 2010 0 0 0 0 0 0 0 0 0 0 0 0 ...

  2. Geology and hydrocarbon potential of the Sepik-Ramu area, Ramu basin, Papua New Guinea

    SciTech Connect (OSTI)

    Donaldson, J.C.; Wilson, J.T. )

    1990-06-01

    Improvements in seismic processing have made new interpretations of the structural and depositional history of the northwestern portion of the Ramu basin possible. Support for a wrench tectonic model for this area is observed in the reprocessed seismic data. Strike-slip movement along major fault zones has allowed compressional forces to be translated laterally and resulted in only minor deformation occurring in the Sepik-Ramu area. The major tectonic event is thought to have occurred during late Miocene-early Pliocene, and not during the middle Miocene, as earlier hypothesized. Consequently, Miocene deposition is postulated to have occurred uninterrupted by periods of erosion. A thick Miocene section is preserved in this region and is postulated to contain slope, reef, and shelf carbonates of early to middle Miocene age. This interpretation has led to the identification of a reef trend over 7 mi wide and at least 42 mi long containing numerous pinnacle reefs. The pinnacle reefs are analogous to those found in the Salawati basin of Irian Jaya, Indonesia. The reefs are overlain by deep-water shales, a combination that provides potential reservoirs and seals necessary for the entrapment of hydrocarbons. The presence of oil and gas seeps document the existence of a source. These three factors justify hydrocarbon exploration in this area. The numerous potential drilling targets may lead to the discovery of significant quantities of hydrocarbons.

  3. Papua New Guinea-ClimateWorks Low Carbon Growth Planning Support...

    Open Energy Info (EERE)

    Organization ClimateWorks, Project Catalyst, McKinsey and Company Sector Energy, Land Topics Background analysis, Low emission development planning, Policiesdeployment...

  4. 123 Agreements for Peaceful Cooperation | National Nuclear Security...

    National Nuclear Security Administration (NNSA)

    Italy, Latvia, Lithuania, Luxembourg, Malta, the Netherlands, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, and the United Kingdom. 2 Pursuant to Section 6 of ...

  5. Microsoft Word - Foreign Obligation Codes.docx

    National Nuclear Security Administration (NNSA)

    Greece, Hungary, Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, the Netherlands, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, and the United Kingdom.

  6. Microsoft PowerPoint - 10_ROSE_MARTYN_UPDATED_NMMSS_2014_Foreign...

    National Nuclear Security Administration (NNSA)

    ... Hungary, Latvia, Lithuania, Luxembourg, Malta, The Netherlands, Poland, Portugal, Romania, Slovak Republic, Slovenia, Spain, Sweden and The United Kingdom NMMSS Obligation ...

  7. Integrated Precipitation and Hydrology Experiment (IPHEx)/Orographic...

    Office of Scientific and Technical Information (OSTI)

    and Space Administration (NASA) Global Precipitation Mission (GPM) Ground Validation (GV) field campaign after the launch of the GPM Core Satellite (Barros et al. 2014). ...

  8. Tracy, California: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    Powerworks Inc Pacific Winds Energy Generation Facilities in Tracy, California GV1 Solar Power Plant Tracy Biomass Facility References US Census Bureau Incorporated place and...

  9. ,"Price of U.S. Liquefied Natural Gas Imports From Equatorial...

    U.S. Energy Information Administration (EIA) Indexed Site

    Equatorial Guinea (Dollars per Thousand Cubic Feet)" ,"Click worksheet name or tab at ... Natural Gas Imports From Equatorial Guinea (Dollars per Thousand Cubic ...

  10. National Action Programmes on Desertification | Open Energy Informatio...

    Open Energy Info (EERE)

    Faso, Burundi, Cameroon, Cape Verde, Chad, Democratic Republic of Congo, Djibouti, Egypt, Equatorial Guinea, Eritrea, Ethiopia, Gabon, Gambia, Ghana, Guinea, Kenya, Lesotho,...

  11. Soro West: A non-seismically defined, fault cut-off prospect in the Papuan Fold and Thrust Belt, Papua New Guinea

    SciTech Connect (OSTI)

    Robinson, W.F.; Swift, C.M. Jr.

    1996-12-31

    Soro West is a fault cut-off prospect located in the frontal portion of the Papuan Fold and Thrust Belt. Prospective Toro and Imburu sandstones are interpreted to be in the hanging wall of the Soro Thrust. Truncation against the thrust, both updip and through lateral ramps, provides the trapping mechanism. The Soro West Prospect was defined using geological, geochemical, remote sensing, and geophysical data. The definition and location of the trap is a primary risk and work was focused on this aspect. Surface geological data (lithology, strikes, and dips) topography and synthetic aperture radar imagery were incorporated into the evaluation. Statistical curvature analysis techniques helped define the shape of the structure and the locations of the lateral ramps. Strontium isotope analyses of Darai Limestone surface samples refined erosional levels using a locally-derived reference curve. Severe karst precludes the acquisition of coherent surface seismic data, so the primary geophysical tool used was magnetotellurics (MT). A detailed, pre-survey feasibility study defined expected responses from alternative structural models. The MT data demonstrated that the limestone at surface is underlain by thick conductive clastics and not another Darai Limestone sheet. The data also constrained the range of fault cut-off positions significantly. Multiple, three-dimensionally consistent, restorable alternative structural models were created using results from all analyses. These led to a positive assessment of the prospect and an exploratory test is to be drilled in 1996.

  12. Soro West: A non-seismically defined, fault cut-off prospect in the Papuan Fold and Thrust Belt, Papua New Guinea

    SciTech Connect (OSTI)

    Robinson, W.F. ); Swift, C.M. Jr. )

    1996-01-01

    Soro West is a fault cut-off prospect located in the frontal portion of the Papuan Fold and Thrust Belt. Prospective Toro and Imburu sandstones are interpreted to be in the hanging wall of the Soro Thrust. Truncation against the thrust, both updip and through lateral ramps, provides the trapping mechanism. The Soro West Prospect was defined using geological, geochemical, remote sensing, and geophysical data. The definition and location of the trap is a primary risk and work was focused on this aspect. Surface geological data (lithology, strikes, and dips) topography and synthetic aperture radar imagery were incorporated into the evaluation. Statistical curvature analysis techniques helped define the shape of the structure and the locations of the lateral ramps. Strontium isotope analyses of Darai Limestone surface samples refined erosional levels using a locally-derived reference curve. Severe karst precludes the acquisition of coherent surface seismic data, so the primary geophysical tool used was magnetotellurics (MT). A detailed, pre-survey feasibility study defined expected responses from alternative structural models. The MT data demonstrated that the limestone at surface is underlain by thick conductive clastics and not another Darai Limestone sheet. The data also constrained the range of fault cut-off positions significantly. Multiple, three-dimensionally consistent, restorable alternative structural models were created using results from all analyses. These led to a positive assessment of the prospect and an exploratory test is to be drilled in 1996.

  13. Category:Economic Community of West African States | Open Energy...

    Open Energy Info (EERE)

    15 pages are in this category, out of 15 total. B Benin Burkina Faso C Cape Verde G Gambia Ghana G cont. Guinea Guinea-Bissau I Ivory Coast L Liberia M Mali N Niger Nigeria...

  14. U.S. Natural Gas Imports by Country

    U.S. Energy Information Administration (EIA) Indexed Site

    Equatorial Guinea 0 0 0 0 0 0 2007-2016 Indonesia 0 0 0 0 0 0 1997-2016 Malaysia 0 0 0 0 0 ... Equatorial Guinea -- -- -- -- -- -- 2007-2016 Indonesia -- -- -- -- -- -- 1997-2016 ...

  15. PSA Vol 1 Tables Revised Ver 2 Print.xls

    Gasoline and Diesel Fuel Update (EIA)

    11 0 -2 0 0 -1 -1 Honduras 0 0 -1 0 0 -3 -3 India 0 0 0 8 0 2 2 Italy 0 0 0 3 0 16 16 Japan 0 0 0 0 0 1 1 Korea, South 0 0 0 1 0 4 4 Latvia 0 0 0 0 1 0 1 Lithuania 0 0 0 0 0 19...

  16. untitled

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    0 0 -2 0 0 0 0 Honduras 0 0 -1 0 0 -3 -3 India 0 0 0 0 0 0 0 Italy 0 0 0 15 0 21 21 Japan 0 0 0 0 0 0 0 Korea, South 0 0 0 0 0 16 16 Latvia 0 0 0 0 0 0 0 Lithuania 0 0 0 0 0 7...

  17. untitled

    Gasoline and Diesel Fuel Update (EIA)

    14 0 -2 0 0 -1 -1 Honduras 0 0 -1 0 0 -3 -3 India 0 0 0 3 0 1 1 Italy 0 0 0 3 0 16 16 Japan 0 0 0 1 0 0 0 Korea, South 0 0 0 0 0 5 5 Latvia 0 0 0 0 0 0 0 Lithuania 0 0 0 0 0 16...

  18. untitled

    Gasoline and Diesel Fuel Update (EIA)

    0 0 -5 0 0 -1 -1 Honduras 0 0 -1 0 0 -3 -3 India 0 0 0 0 0 0 0 Italy 0 0 -2 0 1 5 6 Japan 0 0 0 0 0 0 0 Korea, South 0 0 0 0 0 0 0 Latvia 0 0 0 0 0 0 0 Lithuania 0 0 0 0 0 10...

  19. untitled

    Gasoline and Diesel Fuel Update (EIA)

    11 0 -2 0 0 -1 -1 Honduras 0 0 -1 0 0 -3 -3 India 0 0 0 8 0 2 2 Italy 0 0 0 3 0 17 17 Japan 0 0 0 0 0 1 1 Korea, South 0 0 0 1 0 4 4 Latvia 0 0 0 0 1 0 1 Lithuania 0 0 0 0 0 17...

  20. FSU/Eastern Europe: Russia spearheads small upturn

    SciTech Connect (OSTI)

    1996-08-01

    The paper discusses the political and legal scene in Russia, domestic restructuring, exploration, drilling, development by Western companies and by Russian companies, and production. Exploration and development in Azerbaijan, Kazakhstan, Turkmenistan, Ukraine, Armenia, Belarus, Georgia, Kyrgyzstan, Latvia, Lithuania, Moldova, Tajikistan, Uzbekistan, Albania, Bulgaria, Croatia, Czech Republic, Hungary, Poland, Romania, Slovakia, Slovenia, and Serbia are also discussed.

  1. Spatial and kinematic distributions of transition populations in intermediate redshift galaxy clusters

    SciTech Connect (OSTI)

    Crawford, Steven M.; Wirth, Gregory D.; Bershady, Matthew A. E-mail: wirth@keck.hawaii.edu

    2014-05-01

    We analyze the spatial and velocity distributions of confirmed members in five massive clusters of galaxies at intermediate redshift (0.5 < z < 0.9) to investigate the physical processes driving galaxy evolution. Based on spectral classifications derived from broad- and narrow-band photometry, we define four distinct galaxy populations representing different evolutionary stages: red sequence (RS) galaxies, blue cloud (BC) galaxies, green valley (GV) galaxies, and luminous compact blue galaxies (LCBGs). For each galaxy class, we derive the projected spatial and velocity distribution and characterize the degree of subclustering. We find that RS, BC, and GV galaxies in these clusters have similar velocity distributions, but that BC and GV galaxies tend to avoid the core of the two z ? 0.55 clusters. GV galaxies exhibit subclustering properties similar to RS galaxies, but their radial velocity distribution is significantly platykurtic compared to the RS galaxies. The absence of GV galaxies in the cluster cores may explain their somewhat prolonged star-formation history. The LCBGs appear to have recently fallen into the cluster based on their larger velocity dispersion, absence from the cores of the clusters, and different radial velocity distribution than the RS galaxies. Both LCBG and BC galaxies show a high degree of subclustering on the smallest scales, leading us to conclude that star formation is likely triggered by galaxy-galaxy interactions during infall into the cluster.

  2. --No Title--

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Nicaragua Niger Nigeria Niue Norway Oman Pakistan Palestine Panama Papua New Guinea Paraguay Peru Philippines Poland Portugal Puerto Rico Qatar Reunion Romania Russia Rwanda...

  3. Category:Countries | Open Energy Information

    Open Energy Info (EERE)

    Korea Northern Mariana Islands Norway O Oman P Pakistan Palau Panama Papua New Guinea Paraguay Peru Philippines Pitcairn Poland Portugal Puerto Rico Q Qatar R Republic of Macedonia...

  4. LUG 2015 | Registration

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Norway Oman Pakistan Palau Palestinian Territory, Occupied Panama Papua New Guinea Paraguay Peru Philippines Pitcairn Poland Portugal Puerto Rico Qatar Reunion Romania Russian...

  5. Utility Rate Database | Open Energy Information

    Open Energy Info (EERE)

    Islands Norway Oman Pakistan Palau Palestinian Territories Panama Papua New Guinea Paraguay Peru Philippines Pitcairn Islands Poland Portugal Puerto Rico Qatar Romania Russia...

  6. Forest Carbon Partnership Facility | Open Energy Information

    Open Energy Info (EERE)

    Madagascar, Mexico, Moldova, Mozambique, Nepal, Nicaragua, Panama, Papua New Guinea, Paraguay, Peru, Republic of the Congo, Suriname, Tanzania, Thailand, Uganda, Vanuatu, Vietnam...

  7. Substrate-Induced Band-Gap Opening in Epitaxial Graphene

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Technology), D.-H. Lee (University of California, Berkeley), F. Guinea (Instituto de Ciencia de Materiales de Madrid, Spain), and A.H. Castro Neto (Boston University). Research...

  8. Orbital two-channel Kondo effect in epitaxial ferromagnetic L10...

    Office of Scientific and Technical Information (OSTI)

    ... The 2-channel Kondo model: I. Review of experimental evidence for its realization in metal nanoconstrictions. Annas. Phys. 263, 1-55 (1998). 13. Muramatsu, A. & Guinea, F. ...

  9. Lihir Geothermal Power Plant | Open Energy Information

    Open Energy Info (EERE)

    Lihir Geothermal Power Plant General Information Name Lihir Geothermal Power Plant Sector Geothermal energy Location Information Location Lihir Island, Papua New Guinea Coordinates...

  10. U.S.-Africa Energy Ministerial Co-Chairs' Summary from Energy...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    the Democratic Republic of the Congo, the Republic of Djibouti, the Arab Republic of Egypt, the Republic of Equatorial Guinea, the Gabonese Republic, the Republic of the Gambia,...

  11. Total Crude Oil and Products Imports from All Countries

    U.S. Energy Information Administration (EIA) Indexed Site

    Costa Rica Croatia Curacao Cyprus Czech Republic Denmark Dominican Republic Egypt El Salvador Equatorial Guinea Estonia Finland France French Guiana Gabon Georgia, Republic ...

  12. Total Net Imports of Crude Oil and Petroleum Products into the...

    U.S. Energy Information Administration (EIA) Indexed Site

    Rica Croatia Cyprus Czech Republic Denmark Djbouti Dominica Dominican Republic Egypt El Salvador Equatorial Guinea Ethiopia Eritrea Estonia Falkland Islands Fiji Finland France ...

  13. Total All Countries Exports of Crude Oil and Petroleum Products...

    U.S. Energy Information Administration (EIA) Indexed Site

    Curacao Cyprus Czech Republic Denmark Djbouti Dominica Dominican Republic Ecuador Egypt El Salvador Equatorial Guinea Eritrea Estonia Ethiopia Falkland Islands Fiji Finland France ...

  14. U.S. Imports from All Countries

    U.S. Energy Information Administration (EIA) Indexed Site

    Costa Rica Croatia Curacao Cyprus Czech Republic Denmark Dominican Republic Egypt El Salvador Equatorial Guinea Estonia Finland France French Guiana Gabon Georgia, Republic ...

  15. --No Title--

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    Cyprus Czech Republic Denmark Djibouti Dominica Dominican Republic Ecuador Egypt El Salvador Equatorial Guinea Eritrea Estonia Ethiopia Falkland Islands (Islas Malvinas) Faroe...

  16. ARM - Feature Stories and Releases Article

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    study's range to include Manus Island in Papua New Guinea, where the MJO strengthens again after weakening over the area around Indonesia and the Philippines known as the ...

  17. Western Pacific; Gas line plans continue to increase

    SciTech Connect (OSTI)

    Quarles, W.R.; Thiede, K.; Parent, L.

    1990-11-01

    The authors report on pipeline activity in the Western Pacific. They discuss projects underway in Australia, Indonesia, Malaysia, New Zealand, Papua New Guinea, and Singapore.

  18. EIA-814

    U.S. Energy Information Administration (EIA) Indexed Site

    ... ,,,"Panama",710,"PM",3205 ,,,"Papua New Guinea",712,"PP",3203 ,,,"Paraguay",715,"PA",3204 ,,,"Peru",720,"PE",3201 ,,,"Philippines",725,"RP",3295 ...

  19. Natural Gas Weekly Update, Printer-Friendly Version

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    or 75 percent of all deliveries. In recent years, several African countries, including Egypt, Equatorial Guinea, Nigeria, and Algeria, also have been suppliers of LNG to the...

  20. DOE - Fossil Energy:

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    States. The United States imports natural gas from Canada, Mexico, Algeria, Australia, Egypt, Equatorial Guinea, Malaysia, Nigeria, Norway, Oman, Qatar, Trinidad and Tobago, and...

  1. SREL Reprint #3203

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Science, Amherst, Massachusetts, USA 4Bulmer and Associates, Auckland, New Zealand Abstract: In 1957, Troughton described the wild dog of New Guinea, naming it Canis hallstromi. ...

  2. SNL-ESSC (Sandia National Laboratories - Extreme Sea State Contour...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... Panama Papua New Guinea Paraguay Peru Philippines Poland Portugal Puerto Rico Qatar Romania Russia Rwanda Saint Kitts and Nevis Saint Lucia Saint Vincent and the Grenadines Samoa ...

  3. Total Crude Oil and Products Imports from All Countries

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    Oman Pakistan Panama Papua New Guinea Peru Philippines Poland Portugal Puerto Rico Romania Russia Senegal Singapore Slovakia South Africa Spain Spratly Islands Suriname ...

  4. Offshore Wind RD&D: Large Offshore Rotor Development

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... Panama Papua New Guinea Paraguay Peru Philippines Poland Portugal Puerto Rico Qatar Romania Russia Rwanda Saint Kitts and Nevis Saint Lucia Saint Vincent and the Grenadines Samoa ...

  5. EC Publications

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... Panama Papua New Guinea Paraguay Peru Philippines Poland Portugal Puerto Rico Qatar Romania Russia Rwanda Saint Kitts and Nevis Saint Lucia Saint Vincent and the Grenadines Samoa ...

  6. MELCOR / CSARP / MCAP / IMUG Meetings 2016

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... Panama Papua New Guinea Paraguay Peru Philippines Poland Portugal Puerto Rico Qatar Romania Russia Rwanda Saint Kitts and Nevis Saint Lucia Saint Vincent and the Grenadines Samoa ...

  7. ARM - TWP Manus Site-Inactive

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Western Pacific locale was established. The Manus facility was located at Momote Airport on Los Negros Island in Manus Province, Papua New Guinea (PNG). This location was...

  8. ARM - Publications: Science Team Meeting Documents

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    New Guinea and Republic of Nauru, the TWP Office has developed stable power and reliable communications systems to continuously operate an extensive suite of in-situ instruments,...

  9. U.S. Price of Liquefied Natural Gas Imports by Point of Entry

    U.S. Energy Information Administration (EIA) Indexed Site

    Freeport, TX 2011-2011 Gulf LNG, MS 2011-2011 From Equatorial Guinea -- -- -- -- -- -- 2007-2016 From Indonesia -- -- -- -- -- -- 1997-2016 From Malaysia -- -- -- -- -- -- ...

  10. Re-appraisal and extension of the Gratton-Vargas two-dimensional analytical snowplow model of plasma focus evolution in the context of contemporary research

    SciTech Connect (OSTI)

    Auluck, S. K. H.

    2013-11-15

    Recent resurgence of interest in applications of dense plasma focus and doubts about the conventional view of dense plasma focus as a purely irrotational compressive flow have re-opened questions concerning device optimization. In this context, this paper re-appraises and extends the analytical snowplow model of plasma focus sheath evolution developed by F. Gratton and J. M. Vargas [Energy Storage, Compression and Switching, edited by V. Nardi, H. Sahlin, and W. H. Bostick (Plenum, New York, 1983), Vol. 2, p. 353)] and shows its relevance to contemporary research. The Gratton-Vargas (GV) model enables construction of a special orthogonal coordinate system in which the plasma flow problem can be simplified and a model of sheath structure can be formulated. The Lawrenceville Plasma Physics (LPP) plasma focus facility, which reports neutron yield better than global scaling law, is shown to be operating closer to an optimum operating point of the GV model as compared with PF-1000.

  11. 1

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    is next to the Pacific "warm pool" - off the coast of Papua New Guinea, just north of Australia. The "warm pool" is important because it gives off heat and moisture to the...

  12. Workbook Contents

    U.S. Energy Information Administration (EIA) Indexed Site

    Natural Gas Imports From Canada (MMcf)","U.S. Liquefied Natural Gas Imports From Egypt (MMcf)","U.S. Liquefied Natural Gas Imports From Equatorial Guinea (MMcf)","U.S....

  13. User:GregZiebold/Developing Country Programs Map | Open Energy...

    Open Energy Info (EERE)

    of Congo 12 Djibouti 3 Dominica 9 Dominican Republic 12 Ecuador 7 Egypt 14 El Salvador 8 Equatorial Guinea 4 Eritrea 3 Estonia 2 Ethiopia 21 Fiji 1 Gabon 10 ... further...

  14. Posters

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... westward flow of the SEC, the southward Ekman drift and coastal currents off New Guinea. ... Finally, the eastern Indian Ocean (region I) receives the largest net surface heat flux ...

  15. DOE - Fossil Energy:

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of Equatorial Guinea BG LNG Services, LLC 2288 FE06-05-LNG 010606 Arab Republic of Egypt BG LNG Services, LLC 2287 FE06-04-LNG 010606 Trinidad and Tobago BG LNG Services,...

  16. ,"U.S. Crude Oil Imports"

    U.S. Energy Information Administration (EIA) Indexed Site

    Imports from Denmark of Crude Oil (Thousand Barrels per Day)","U.S. Imports from Egypt of Crude Oil (Thousand Barrels per Day)","U.S. Imports from Equatorial Guinea of Crude...

  17. U.S. Crude Oil Imports

    U.S. Energy Information Administration (EIA) Indexed Site

    (Brazzaville) 24 8 13 20 12 15 1993-2015 Congo (Kinshasa) 1993-2013 Denmark 1997-2004 Egypt 17 1993-2015 Equatorial Guinea 1996-2014 Estonia 1999-1999 Gabon 4 18 1993-2015...

  18. ,"U.S. Crude Oil Imports"

    U.S. Energy Information Administration (EIA) Indexed Site

    Imports from Denmark of Crude Oil (Thousand Barrels)","U.S. Imports from Egypt of Crude Oil (Thousand Barrels)","U.S. Imports from Equatorial Guinea of Crude Oil...

  19. U.S. Total Exports

    U.S. Energy Information Administration (EIA) Indexed Site

    GA Freeport, TX Gulf LNG, MS LNG Imports from Equatorial Guinea LNG Imports from Indonesia LNG Imports from Malaysia LNG Imports from Nigeria Cove Point, MD LNG Imports from ...

  20. Jacob P. Fugal, Scott Spuler Earth Observing Laboratory NCAR, Boulder, CO USA

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    airborne digital holographic instrument for measuring the spatial distribution and local size distributions of cloud particles: Holographic Detector for Clouds 2 (HOLODEC 2) Jacob P. Fugal, Scott Spuler Earth Observing Laboratory NCAR, Boulder, CO USA & Raymond A. Shaw Physics Department, michigan Tech Houghton, MI USA C-130 Hercules Q HIAPER Gulfstream GV HOLODEC (Holographic Detector for Clouds) is an airborne instrument that measures the size, shape, and relative 3D position of cloud

  1. Strangelet search in S-W collisions at 200[ital A] GeV/[ital c

    SciTech Connect (OSTI)

    Borer, K.; Dittus, F.; Frei, D.; Hugentobler, E.; Klingenberg, R.; Moser, U.; Pretzl, K.; Schacher, J.; Stoffel, F.; Volken, W. ); Elsener, K.; Lohmann, K.D. ); Baglin, C.; Bussiere, A.; Guillaud, J.P. ); Appelquist, G.; Bohm, C.; Hovander, B.; Sellden, B.; Zhang, Q.P. )

    1994-03-07

    A search for new massive particles with a low charge to mass ratio in S-W collisions at a beam momentum of 200 GeV/[ital c] per nucleon is presented. Upper limits for the production of strangelets with a mass to charge ratio of up to 60 GeV/[ital c][sup 2] at rigidities of [plus minus]150 GV are reported.

  2. Industry turns its attention south

    SciTech Connect (OSTI)

    Marhefka, D.

    1997-08-01

    The paper discusses the outlook for the gas and oil industries in the Former Soviet Union and Eastern Europe. Significant foreign investment continues to elude Russia`s oil and gas industry, so the Caspian nations of Kazakhstan and Azerbaijan are picking up the slack, welcoming the flow of foreign capital to their energy projects. Separate evaluations are given for Russia, Azerbaijan, Kazakhstan, Turkmenistan, Ukraine, Armenia, Belarus, Georgia, Lithuania, Latvia, Estonia, Moldova, Tajikstan, Uzbekistan, Albania, Bulgaria, Croatia, Czech Republic, Hungary, Poland, Romania, Slovakia, Slovenia, and Serbia.

  3. icenes2011_poster_shumlak_v1_mac.ppt

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Sheared Flow Stabilized Z-Pinch U. Shumlak, J. Chadney, R.P. Golingo, D.J. Den Hartog, M.C. Hughes, S.D. Knecht, B.A. Nelson, W. Lowrie, R.J. Oberto, M.P. Ross, J.L. Rohrbach, and G.V. Vogman Aerospace & Energetics Research Program University of Washington, Seattle, USA 15 th Int'l Conf. on Emerging Nuclear Energy Systems 15 - 19 May 2011 ZaP Personnel Graduate Students Joshua Chadney Sean Knecht Michal Hughes Jacob Rohrbach Michael Ross Undergraduate Students Rachel Oberto Gautam Shah Genia

  4. High power couplers for Project X

    SciTech Connect (OSTI)

    Kazakov, S.; Champion, M.S.; Yakovlev, V.P.; Kramp, M.; Pronitchev, O.; Orlov, Y.; /Fermilab

    2011-03-01

    Project X, a multi-megawatt proton source under development at Fermi National Accelerator Laboratory. The key element of the project is a superconducting (SC) 3GV continuous wave (CW) proton linac. The linac includes 5 types of SC accelerating cavities of two frequencies.(325 and 650MHz) The cavities consume up to 30 kW average RF power and need proper main couplers. Requirements and approach to the coupler design are discussed in the report. New cost effective schemes are described. Results of electrodynamics and thermal simulations are presented.

  5. Ecological Studies

    Office of Legacy Management (LM)

    Studies Book 1 Rulison Animal (and Fish) Printout . . Results g4-..*= 9%- mc,-y----T. . , -..-- x.. ? ,.-: ? = . - ; : . * r - . - . ; r = m = - - - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . - . . . s & : " ? - & 3 , ' 4033 - 2 : ; = & . OFF 7 - - . r, .:* : 5-74 \!G,V ; 0 ;--. 21 3 R u l i s o n Animal (and F i s h ) R e s u l t s P r i n t o u t E x7mp ! @ I I j l v 2 SWRHL-03 RULISON COLORADO ANIMAL RESULTS COLO FI-1-FISH 54024604505860075438 04 26

  6. Turmoil doesn`t dampen enthusiasm

    SciTech Connect (OSTI)

    1997-08-01

    The paper discusses the outlook for the African gas and oil industries. Though Africa remains politically and economically volatile, its vast energy potential is becoming increasingly attractive to foreign oil and gas companies. Separate evaluations are given for Algeria, Egypt, Nigeria, Angola, Libya, Congo, Gabon, Tunisia, Cameroon, Cote D`Ivoire, and briefly for South Africa, Sudan, Equatorial Guinea, Ghana, Zaire, Benin, Mozambique, Chad, Namibia, Tanzania, Eritrea, Guinea-Bissau, Senegal, Morocco, Sao Tome and Principe, Ethiopia, Niger, Madagascar, Rwanda, Mauritania, Seychelles, Uganda, and Liberia.

  7. The GALAXIE all-optical FEL project

    SciTech Connect (OSTI)

    Rosenzweig, J. B.; Arab, E.; Andonian, G.; Cahill, A.; Fitzmorris, K.; Fukusawa, A.; Hoang, P.; Jovanovic, I.; Marcus, G.; Marinelli, A.; Murokh, A.; Musumeci, P.; Naranjo, B.; O'Shea, B.; O'Shea, F.; Ovodenko, A.; Pogorelsky, I.; Putterman, S.; Roberts, K.; Shumail, M.; and others

    2012-12-21

    We describe a comprehensive project, funded under the DARPA AXiS program, to develop an all-optical table-top X-ray FEL based on dielectric acceleration and electromagnetic undulators, yielding a compact source of coherent X-rays for medical and related applications. The compactness of this source demands that high field (>GV/m) acceleration and undulation-inducing fields be employed, thus giving rise to the project's acronym: GV/m AcceLerator And X-ray Integrated Experiment (GALAXIE). There are numerous physics and technical hurdles to surmount in this ambitious scenario, and the integrated solutions include: a biharmonic photonic TW structure, 200 micron wavelength electromagnetic undulators, 5 {mu}m laser development, ultra-high brightness magnetized/asymmetric emittance electron beam generation, and SASE FEL operation. We describe the overall design philosophy of the project, the innovative approaches to addressing the challenges presented by the design, and the significant progress towards realization of these approaches in the nine months since project initialization.

  8. U.S. Total Crude Oil and Products Imports

    U.S. Energy Information Administration (EIA) Indexed Site

    Denmark 2 1 1 3 1 1 1997-2015 Dominican Republic 0 1 1 2 1 1 2009-2015 Egypt 10 4 31 4 2 1993-2015 El Salvador 0 1 2 1 2004-2013 Equatorial Guinea 58 23 41 17 4 6 1996-2015 Estonia ...

  9. U.S. Total Crude Oil and Products Imports

    U.S. Energy Information Administration (EIA) Indexed Site

    Dominican Republic 103 273 210 588 267 224 2009-2015 Egypt 3,537 1,616 11,456 1,553 694 1993-2015 El Salvador 150 293 594 365 2004-2013 Equatorial Guinea 21,063 8,500 15,100 6,073 ...

  10. U.S. Products Imports

    U.S. Energy Information Administration (EIA) Indexed Site

    Denmark 2 1 1 3 1 1 1995-2015 Dominican Republic 0 1 1 2 1 1 2009-2015 Egypt 3 0 0 0 1993-2015 El Salvador 0 1 2 1 2004-2013 Equatorial Guinea 8 4 0 0 1 1995-2015 Estonia 11 12 14 ...

  11. U.S. Liquefied Natural Gas Imports by Point of Entry

    U.S. Energy Information Administration (EIA) Indexed Site

    Freeport, TX 2011-2011 Gulf LNG, MS 2011-2011 From Equatorial Guinea 0 0 0 0 0 0 2007-2016 From Indonesia 0 0 0 0 0 0 1997-2016 From Malaysia 0 0 0 0 0 0 1999-2016 From Nigeria 0 0 ...

  12. CRC handbook of agricultural energy potential of developing countries. Volume I

    SciTech Connect (OSTI)

    Duke, J.A.

    1986-01-01

    The contents of this book are: Introduction, Argentina, Bangladesh, Benin, Bolivia, Botswana, Bourkina (Upper Volta), Brazil, Burma, Burundi, Cameroon, Chad, Chile, Columbia, Costa Rica, Djibouti, Dominican Republic, Ecuador, El Salvador, Ethiopia, French Guiana, Gambia, Ghana, Guatemala, Guinea, Guyana, Haiti, Honduras, India, Indonesia, Jamaica, Appendix I. Conventional and Energetic Yields, Appendix II, Phytomass Files, and References.

  13. Minerals yearbook: Mineral industries of Europe and central Eurasia. Volume 3. 1992 international review

    SciTech Connect (OSTI)

    Not Available

    1992-01-01

    Volume III, Minerals Yearbook -- International Review contains the latest available mineral data on more than 175 foreign countries and discusses the importance of minerals to the economies of these nations. Since the 1989 International Review, the volume has been presented as six reports. The report presents the Mineral Industries of Europe and Central Eurasia. The report incorporates location maps, industry structure tables, and an outlook section previously incorporated in the authors' Minerals Perspectives Series quinquennial regional books, which are being discontinued. This section of the Minerals Yearbook reviews the minerals industries of 45 countries: the 12 nations of the European Community (EC); 6 of the 7 nations of the European Free Trade Association (EFTA); Malta; the 11 Eastern European economies in transition (Albania, Bosnia and Hercegovina, Bulgaria, Croatia, Czechoslovakia, Hungary, Macedonia, Poland, Romania, Serbia and Montenegro, and Slovenia); and the countries of Central Eurasia (Armenia, Azerbaijan, Belarus, Estonia, Georgia, Kazakhstan, Kyrgystan, Latvia, Lithuania, Moldova, Russia, Tajikistan, Turkmenistan, Ukraine, and Uzbekistan).

  14. Mazheikiai refinery modernization study. Executive summary. Export trade information

    SciTech Connect (OSTI)

    Not Available

    1994-01-01

    The study, conducted by Foster Wheeler Corporation, was funded by the U.S. Trade and Development Agency on behalf of Lithuania's Ministry of Energy. The Mazheikiai Oil Refinery is the only one in the Baltic Region and serves the needs of Lithuania, Latvia, Estonia, and Kaliningrad. Before Lithuania's independence in 1990, the refinery was assured of crude supplies from Russia. However, since then the need has arisen to secure alternate sources of crude oil and the ability to process them. The purpose of the report is to provide recommendations to the Ministry of Energy for process improvements, environmental control measures, physical rehabilitation and energy conservation plans for the Mazheikiai Oil Refinery. The volume contains the Executive Summary.

  15. Mazheikiai refinery modernization study. Final report. Volume 2. Export trade information

    SciTech Connect (OSTI)

    Not Available

    1994-01-01

    The study, conducted by Foster Wheeler Corporation, was funded by the U.S. Trade and Development Agency on behalf of Lithuania's Ministry of Energy. The Mazheikiai Oil Refinery is the only one in the Baltic Region and serves the needs of Lithuania, Latvia, Estonia, and Kaliningrad. Before Lithuania's independence in 1990, the refinery was assured of crude supplies from Russia. However, since then the need has arisen to secure alternate sources of crude oil and the ability to process them. The purpose of the report is to provide recommendations to the Ministry of Energy for process improvements, environmental control measures, physical rehabilitation and energy conservation plans for the Mazheikiai Oil Refinery. This is Volume 2 of the study.

  16. Mazheikiai refinery modernization study. Final report. Volume 3. Export trade information

    SciTech Connect (OSTI)

    Not Available

    1994-01-01

    The study, conducted by Foster Wheeler Corporation, was funded by the U.S. Trade and Development Agency on behalf of Lithuania's Ministry of Energy. The Mazheikiai Oil Refinery is the only one in the Baltic Region and serves the needs of Lithuania, Latvia, Estonia, and Kaliningrad. Before Lithuania's independence in 1990, the refinery was assured of crude supplies from Russia. However, since then the need has arisen to secure alternate sources of crude oil and the ability to process them. The purpose of the report is to provide recommendations to the Ministry of Energy for process improvements, environmental control measures, physical rehabilitation and energy conservation plans for the Mazheikiai Oil Refinery. This is Volume 3 of the study.

  17. Soviet delays raise prices

    SciTech Connect (OSTI)

    Young, I.

    1992-01-15

    The breakup of the Soviet Union is causing massive disruptions to methanol exports. The changeover to a Commonwealth of independent States has created logistical problems which have led some shipments of Russian methanol to be cancelled and delayed other deliveries by up to two weeks. In recent years the Soviet Union has exported 700,000 m.t./year-900,000 m.t./year of methanol, mainly to Western Europe. The product is made at 750,000-m.t./year plants at Tomsk and Gubakha in Russia and transported by rail for shipment from the ports of Ventspils, Latvia, on the Baltic Sea and Yuzhnyy in Ukraine, on the Black Sea. The exports were handled by state export agency Soyuzagrochim, mainly under contract to West European traders and consumers in areas like Scandinavia and France.

  18. Mazheikiai refinery modernization study. Final report. Volume 1. Export trade information

    SciTech Connect (OSTI)

    Not Available

    1994-01-01

    The study, conducted by Foster Wheeler Corporation, was funded by the U.S. Trade and Development Agency on behalf of Lithuania's Ministry of Energy. The Mazheikiai Oil Refinery is the only one in the Baltic Region and serves the needs of Lithuania, Latvia, Estonia, and Kaliningrad. Before Lithuania's independence in 1990, the refinery was assured of crude supplies from Russia. However, since then the need has arisen to secure alternate sources of crude oil and the ability to process them. The purpose of the report is to provide recommendations to the Ministry of Energy for process improvements, environmental control measures, physical rehabilitation and energy conservation plans for the Mazheikiai Oil Refinery. This is Volume 1 of the study.

  19. Midlatitude Continental Convective Clouds Experiment (MC3E)

    SciTech Connect (OSTI)

    Jensen, MP; Petersen, WA; Del Genio, AD; Giangrande, SE; Heymsfield, A; Heymsfield, G; Hou, AY; Kollias, P; Orr, B; Rutledge, SA; Schwaller, MR; Zipser, E

    2010-04-10

    The Midlatitude Continental Convective Clouds Experiment (MC3E) will take place in central Oklahoma during the AprilMay 2011 period. The experiment is a collaborative effort between the U.S. Department of Energy (DOE) Atmospheric Radiation Measurement (ARM) Climate Research Facility and the National Aeronautics and Space Administrations (NASA) Global Precipitation Measurement (GPM) mission Ground Validation (GV) program. The field campaign leverages the unprecedented observing infrastructure currently available in the central United States, combined with an extensive sounding array, remote sensing and in situ aircraft observations, NASA GPM ground validation remote sensors, and new ARM instrumentation purchased with American Recovery and Reinvestment Act funding. The overarching goal is to provide the most complete characterization of convective cloud systems, precipitation, and the environment that has ever been obtained, providing constraints for model cumulus parameterizations and space-based rainfall retrieval algorithms over land that have never before been available.

  20. Ionization-Induced Electron Trapping inUltrarelativistic Plasma Wakes

    SciTech Connect (OSTI)

    Oz, E.; Deng, S.; Katsouleas, T.; Muggli, P.; Barnes, C.D.; Blumenfeld, I.; Decker, F.J.; Emma, P.; Hogan, M.J.; Ischebeck, R.; Iverson, R.H.; Kirby, N.; Krejcik, P.; O'Connell, C.; Siemann, R.H.; Walz, D.; Auerbach, D.; Clayton, C.E.; Huang, C.; Johnson, D.K.; Joshi, C.; /UCLA

    2007-04-06

    The onset of trapping of electrons born inside a highly relativistic, 3D beam-driven plasma wake is investigated. Trapping occurs in the transition regions of a Li plasma confined by He gas. Li plasma electrons support the wake, and higher ionization potential He atoms are ionized as the beam is focused by Li ions and can be trapped. As the wake amplitude is increased, the onset of trapping is observed. Some electrons gain up to 7.6 GeV in a 30.5 cm plasma. The experimentally inferred trapping threshold is at a wake amplitude of 36 GV/m, in good agreement with an analytical model and PIC simulations.

  1. Beam manipulation and acceleration with Dielectric-Lined Waveguides

    SciTech Connect (OSTI)

    Lemery, Francois

    2015-06-01

    The development of next-generation TeV+ electron accelerators will require either immense footprints based on conventional acceleraton techniques or the development of new higher{gradient acceleration methods. One possible alternative is beam-driven acceleration in a high-impedance medium such as a dielectric-lined-waveguide (DLW), where a highcharge bunch passes through a DLW and can excite gradients on the order of GV/m. An important characteristic of this acceleration class is the transformer ratio which characterizes the energy transfer of the scheme. This dissertation discusses alternative methods to improve the transformer ratio for beam-driven acceleration and also considers the use of DLWs for beam manipulation at low energy.

  2. Charging/discharging behavior and mechanism of silicon quantum dots embedded in amorphous silicon carbide films

    SciTech Connect (OSTI)

    Wen, Xixing; Zeng, Xiangbin Zheng, Wenjun; Liao, Wugang; Feng, Feng

    2015-01-14

    The charging/discharging behavior of Si quantum dots (QDs) embedded in amorphous silicon carbide (a-SiC{sub x}) was investigated based on the Al/insulating layer/Si QDs embedded in a-SiC{sub x}/SiO{sub 2}/p-Si (metal-insulator-quantum dots-oxide-silicon) multilayer structure by capacitance-voltage (C-V) and conductance-voltage (G-V) measurements. Transmission electron microscopy and Raman scattering spectroscopy measurements reveal the microstructure and distribution of Si QDs. The occurrence and shift of conductance peaks indicate the carrier transfer and the charging/discharging behavior of Si QDs. The multilayer structure shows a large memory window of 5.2 eV at ±8 V sweeping voltage. Analysis of the C-V and G-V results allows a quantification of the Coulomb charging energy and the trapped charge density associated with the charging/discharging behavior. It is found that the memory window is related to the size effect, and Si QDs with large size or low Coulomb charging energy can trap two or more electrons by changing the charging voltage. Meanwhile, the estimated lower potential barrier height between Si QD and a-SiC{sub x}, and the lower Coulomb charging energy of Si QDs could enhance the charging and discharging effect of Si QDs and lead to an enlarged memory window. Further studies of the charging/discharging mechanism of Si QDs embedded in a-SiC{sub x} can promote the application of Si QDs in low-power consumption semiconductor memory devices.

  3. Theoretical study of thorium monoxide for the electron electric dipole moment search: Electronic properties of H{sup 3}Δ{sub 1} in ThO

    SciTech Connect (OSTI)

    Skripnikov, L. V. Titov, A. V.

    2015-01-14

    Recently, improved limits on the electron electric dipole moment, and dimensionless constant, k{sub T,P}, characterizing the strength of the T,P-odd pseudoscalar–scalar electron–nucleus neutral current interaction in the H{sup 3}Δ{sub 1} state of ThO molecule were obtained by the ACME collaboration [J. Baron et al., Science 343, 269 (2014)]. The interpretation of the experiment in terms of these fundamental quantities is based on the results of theoretical study of appropriate ThO characteristics, the effective electric field acting on electron, E{sub eff}, and a parameter of the T,P-odd pseudoscalar–scalar interaction, W{sub T,P}, given in Skripnikov et al. [J. Chem. Phys. 139, 221103 (2013)] by St. Petersburg group. To reduce the uncertainties of the given limits, we report improved calculations of the molecular state–specific quantities E{sub eff}, 81.5 GV/cm, and W{sub T,P}, 112 kHz, with the uncertainty within 7% of the magnitudes. Thus, the values recommended to use for the upper limits of the quantities are 75.8 GV/cm and 104 kHz, correspondingly. The hyperfine structure constant, molecule-frame dipole moment of the H{sup 3}Δ{sub 1} state, and the H{sup 3}Δ{sub 1} → X{sup 1}Σ{sup +} transition energy which, in general, can serve as a measure of reliability of the obtained E{sub eff} and W{sub T,P} values are also calculated. In addition, we report the first calculation of g-factor for the H{sup 3}Δ{sub 1} state of ThO. The results are compared to the earlier experimental and theoretical studies, and a detailed analysis of uncertainties of the calculations is given.

  4. Capacitance and conductance characterization of nano-ZnGa{sub 2}Te{sub 4}/n-Si diode

    SciTech Connect (OSTI)

    Fouad, S.S.; Sakr, G.B.; Yahia, I.S.; Abdel-Basset, D.M.; Yakuphanoglu, F.

    2014-01-01

    Graphical abstract: - Highlights: XRD and DTA micrographs were used to study the structure of ZnGa{sub 2}Te{sub 4}. CV, GV and R{sub s}V of the diode characteristics have been analyzed for the first time. Dielectric constant, dielectric loss, loss tangent and ac conductivity were determined. The interfaces states were determined using conductancevoltage technique. ZnGa{sub 2}Te{sub 4} is a good candidate for electronic device applications. - Abstract: Capacitancevoltage (CV) and conductancevoltage (GV) characteristics of p-ZnGa{sub 2}Te{sub 4}/n-Si HJD were studied over a wide frequency and temperature. Both the interface states density N{sub ss} and series resistance R{sub s} were strongly frequency and temperature dependent. The interface states density N{sub ss} is decreased with increasing frequency and increase with increasing temperature. The values of the built-in potential (V{sub bi}) were calculated and found to increase with increasing temperature and frequency. The values of capacitance C, conductance G, series resistance R{sub s}, corrected capacitance C{sub ADJ}, corrected conductance G{sub ADJ}, dielectric constant (??), dielectric loss (??), loss tangent (tan ?) and the AC conductivity (?{sub ac}) are strongly dependent on the applied frequency, voltage and temperature. The obtained results show that the locations of N{sub ss} and R{sub s} have a significant effect on the electrical characteristics of the studied diode.

  5. Sandia National Laboratories: News: Publications: Lab Accomplishments:

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Bioscience Facebook Twitter YouTube Flickr RSS News Bioscience Fighting Ebola Contour map showing drive times and Ebola lab coverage in Liberia. Sandia has been providing technical assistance to West Africa as part of the effort to control the Ebola epidemic. In Liberia and Sierra Leone we analyzed infrastructure and laboratory networks to improve sample transport and optimize laboratory placement. In Guinea and Sierra Leone, numerous Sandians served as laboratory coordinators for

  6. Coordinated Airborne Studies in the Tropics (CAST) Field Campaign Report

    Office of Scientific and Technical Information (OSTI)

    (Technical Report) | SciTech Connect SciTech Connect Search Results Technical Report: Coordinated Airborne Studies in the Tropics (CAST) Field Campaign Report Citation Details In-Document Search Title: Coordinated Airborne Studies in the Tropics (CAST) Field Campaign Report The last field campaign held at the U.S. Department of Energy (DOE) Atmospheric Radiation Measurement (ARM) Climate Research Facility site on Manus Island, Papua New Guinea (PNG), was conducted in February 2014 as part of

  7. Costing and pricing electricity in developing countries

    SciTech Connect (OSTI)

    Munasinghe, M.; Rungta, S.

    1984-01-01

    This book compiles the papers presented at a conference on costing and pricing electricity in developing countries. The topics discussed include: Power tariffs, an overview; electricity tariff policy; estimating and using marginal cost pricing concepts; power tariff policy of Philippines, India, Papua New Guinea, Burma, Bangladesh, Indonesia, Korea, Pakistan; Inter-American Development Bank-Electricity tariffs, policies and practices; and costs of supplying electricity and tariff policy in some other countries.

  8. ARM - Visiting the TWP

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    InactiveVisiting the TWP TWP Related Links Facilities and Instruments Manus Island Nauru Island Darwin, AUS ES&H Guidance Statement Operations Science Field Campaigns Year of Tropical Convection Visiting the Site TWP Fact Sheet Images Information for Guest Scientists Contacts Visiting the TWP Nauru Island from the air. Nauru Island from the air. The Tropical Western Pacific site consists of three diverse climate research facilities in Papua New Guinea, the Republic of Nauru, and Australia.

  9. ARM - Who's Teacher Turtle?

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Teacher Turtle? Outreach Home Room News Publications Traditional Knowledge Kiosks Barrow, Alaska Tropical Western Pacific Site Tours Contacts Students Study Hall About ARM Global Warming FAQ Just for Fun Meet our Friends Cool Sites Teachers Teachers' Toolbox Lesson Plans Who's Teacher Turtle? Teacher Turtle lives in the toasty tropical waters, referred to as the Pacific "warm pool," off the coast of Papua New Guinea, just north of Australia. She is one of eight species of sea turtles

  10. The problem of living in a world contaminated with chemicals

    SciTech Connect (OSTI)

    Metcalf, R.L.

    1990-12-31

    The proliferation of xenobiotic chemicals in the global environment poses living problems for each of us aboard {open_quotes}spaceship earth.{close_quotes} Seven case studies are presented that illustrate the magnitude of the problem that can result from waiting to identify toxic hazards until there have been decades of {open_quotes}human guinea pig{close_quotes} exposure. 25 refs., 5 tabs.

  11. ARM - Education Article

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    July 8, 2007 [Education] Climate Research Facility in Papua New Guinea Launches Kiosk Bookmark and Share In 2004, ACRF Education and Outreach worked with Tradewind Communications to film interviews around Manus Island for the kiosk. The Climate Change: Science and Traditional Knowledge kiosk project for the ACRF Tropical Western Pacific sites has come full circle. Four years ago, ACRF Education and Outreach started building educational kiosks to promote awareness and understanding of ARM

  12. ARM - Events Article

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    April 8, 2013 [Events, Facility News] ARM Facility Highlights at EGU General Assembly 2013 Bookmark and Share Where do scientists get their data? The Atmospheric Radiation Measurement (ARM) Climate Research Facility provides continuous data from heavily instrumented fixed sites in the United States (Alaska and Oklahoma), the Tropical Pacific (Australia and Papua New Guinea), and soon in the Azores. These measurements are supplemented through mobile observation facilities and research aircraft at

  13. ARM - Facility News Article

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Climate Education Kiosk Launched on Manus Island Bookmark and Share Staff of the Papua New Guinea National Weather Service pose with the soon-to-be-revealed ARM kiosk. On June 12, 2007, the last of the three ARM educational kiosks in the Tropical Western Pacific was launched in Lorengau, Manus Island. Inspired by a number of studies showing that indigenous people tend to understand and embrace science more fully when presented in the context of traditional ecological knowledge, ARM's educational

  14. Tropical Africa: Land Use, Biomass, and Carbon Estimates for 1980 (NDP-055)

    SciTech Connect (OSTI)

    Brown, S.

    2002-04-16

    This document describes the contents of a digital database containing maximum potential aboveground biomass, land use, and estimated biomass and carbon data for 1980. The biomass data and carbon estimates are associated with woody vegetation in Tropical Africa. These data were collected to reduce the uncertainty associated with estimating historical releases of carbon from land use change. Tropical Africa is defined here as encompassing 22.7 x 10{sup 6} km{sup 2} of the earth's land surface and is comprised of countries that are located in tropical Africa (Angola, Botswana, Burundi, Cameroon, Cape Verde, Central African Republic, Chad, Congo, Benin, Equatorial Guinea, Ethiopia, Djibouti, Gabon, Gambia, Ghana, Guinea, Ivory Coast, Kenya, Liberia, Madagascar, Malawi, Mali, Mauritania, Mozambique, Namibia, Niger, Nigeria, Guinea-Bissau, Zimbabwe (Rhodesia), Rwanda, Senegal, Sierra Leone, Somalia, Sudan, Tanzania, Togo, Uganda, Burkina Faso (Upper Volta), Zaire, and Zambia). The database was developed using the GRID module in the ARC/INFO{trademark} geographic information system. Source data were obtained from the Food and Agriculture Organization (FAO), the U.S. National Geophysical Data Center, and a limited number of biomass-carbon density case studies. These data were used to derive the maximum potential and actual (ca. 1980) aboveground biomass values at regional and country levels. The land-use data provided were derived from a vegetation map originally produced for the FAO by the International Institute of Vegetation Mapping, Toulouse, France.

  15. Oil and gas developments in central and southern Africa in 1987

    SciTech Connect (OSTI)

    Hartman, J.B.; Walker, T.L.

    1988-10-01

    Significant rightholding changes took place in central and southern Africa during 1987. Angola, Benin, Congo, Gabon, Ghana, Guinea, Guinea Bissau, Mauritania, Seychelles, Somali Republic, Tanzania, Zaire, and Zambia announced awards or acreage open for bidding. Decreases in exploratory rightholdings occurred in Cameroon, Congo, Cote d'Ivoire, Equatorial Guinea, Gabon, Kenya, Namibia, South Africa, and Tanzania. More wells and greater footage were drilled in 1987 than in 1986. Total wells increased by 18% as 254 wells were completed compared to 217 in 1986. Footage drilled during the year increased by 46% as about 1.9 million ft were drilled compared to about 1.3 million ft in 1986. The success rate for exploration wells in 1987 improved slightly to 36% compared to 34% in 1986. Significant discoveries were made in Nigeria, Angola, Congo, and Gabon. Seismic acquisition in 1987 was the major geophysical activity during the year. Total oil production in 1987 was 773 million bbl (about 2.1 million b/d), a decrease of 7%. The decrease is mostly due to a 14% drop in Nigerian production, which comprises 60% of total regional production. The production share of OPEC countries (Nigeria and Gabon) versus non-OPEC countries of 67% remained unchanged from 1986. 24 figs., 5 tabs.

  16. Ventilatory function assessment in safety pharmacology: Optimization of rodent studies using normocapnic or hypercapnic conditions

    SciTech Connect (OSTI)

    Goineau, Sonia; Rompion, Sonia; Guillaume, Philippe; Picard, Sandra

    2010-09-15

    Although the whole body plethysmography for unrestrained animals is the most widely used method to assess the respiratory risk of new drugs in safety pharmacology, non-appropriate experimental conditions may mask deleterious side effects of some substances. If stimulant or bronchodilatory effects can be easily evidenced in rodents under standard experimental conditions, i.e. normal air breathing and diurnal phase, drug-induced respiratory depression remains more difficult to detect. This study was aimed at comparing the responsiveness of Wistar rats, Duncan Hartley guinea-pigs or BALB/c mice to the respiratory properties of theophylline (50 or 100 mg/kg p.o.) or morphine (30 mg/kg i.p.) under varying conditions (100% air versus 5% CO{sub 2}-enriched air, light versus dark day phase), in order to select the most appropriate experimental conditions to each species for safety airway investigations. Our results showed that under normocapnia the ventilatory depressant effects of morphine can be easily evidenced in mice, slightly observed in guinea-pigs and not detected in rats in any day phase. Slight hypercapnic conditions enhanced the responsiveness of rats to morphine but not that of guinea-pigs and importantly they did not blunt the airway responsiveness of rats to the stimulation and bronchodilation evoked by theophylline, the most widely used reference agent in safety pharmacology studies. In conclusion, hypercapnic conditions associated with the non-invasive whole body plethysmography should be considered for optimizing the assessment of both the ventilatory depressant potential of morphine-like substances or the respiratory stimulant effects of new drugs in the rat, the most extensively used species in rodent safety and toxicological investigations.

  17. Tropical Western Pacific

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    govSitesTropical Western Pacific TWP Related Links Facilities and Instruments Manus Island Nauru Island Darwin, AUS ES&H Guidance Statement Operations Science Field Campaigns Year of Tropical Convection Visiting the Site TWP Fact Sheet Images Information for Guest Scientists Contacts Tropical Western Pacific-Inactive Manus, Papua New Guinea: 2° 3' 39.64" S, 147° 25' 31.43" E Nauru Island: 0° 31' 15.6" S, 166° 54' 57.60" E Darwin, Australia: 12° 25' 28.56" S,

  18. X:\ARM_19~1\P113-137.WPD

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    7 C/day, 1.5 C/day m 2 55 C 45 C 45 C 65 C Session Papers 125 Figure 1. Map showing analysis domain for GMS OLR data. Basic spatial units are five by five latitude-longitude areas, four of which are shown outlined by solid lines in the area north of Papau New Guinea; the large dot on the equator at 140 E shows the approximate satellite sub-point and the large area outlined between 150E to 180, 20 N to 20 S is the subject of analyses in Figures 2 and 3. Shading shows areas of intense convection

  19. Research Highlight

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Island-Induced Cloud Plumes Influence Tropical Atmospheric Measurements, Surface Radiation Submitter: McFarlane, S. A., U.S. Department of Energy Area of Research: Radiation Processes Working Group(s): Radiative Processes Journal Reference: McFarlane, S.A., Long, C.N., and Flynn, D., Nauru Island Effect Study, Fourteenth ARM Science Team Meeting, March 22 to 26, 2004, Albuquerque, New Mexico. Nauru Island, about 1,200 miles northeast of Papua New Guinea in the western South Pacific, is one of

  20. Asia to see major pipelines in near future

    SciTech Connect (OSTI)

    Friedman, D.R.

    1987-11-30

    Recent discoveries of crude oil and natural gas in Asia and the Far East have spawned a number of major pipeline projects. Many of these are underway or likely to be started in the next few years. The author reviews what is being done in Taiwan, South Korea, Thailand, Malaysia, Indonesia, Papua New Guinea, and China. He says all of the countries discussed are undergoing an overall improvement in the quality of life, demonstrated by changing life styles, and an overall advancement in economic activity as a result of the discovery of oil and the need for pipelines.

  1. Non-OPEC oil supply continues to grow

    SciTech Connect (OSTI)

    Knapp, D.H.

    1995-12-25

    Global reserves of crude oil remain at 1 trillion bbl, according to OGJ`s annual survey of producing countries. Significant gains are in Brazil, Colombia, Congo, Egypt, Libya, Nigeria, Oman, and Papua New Guinea. Decreases were reported by Indonesia, Norway, the U.K., Iran, Canada, Mexico, and the US. Natural gas reserves slipped to 4.9 quadrillion cu ft. The major production trend is a lasting surge from outside of OPEC. This year`s Worldwide Production report begins with a detailed analysis of this crucial development by an international authority. This article discusses the OECD outlook by region and the turnaround in production in the former Soviet Union.

  2. mather-98.pdf

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    3 Analyses of Measurements for the First Year of Operation of the Tropical Western Pacific Atmospheric Radiation and Cloud Station J. H. Mather and T. P. Ackerman Department of Meteorology The Pennsylvania State University University Park, Pennsylvania Introduction The first Tropical Western Pacific Atmospheric Radiation and Cloud Station (TWP ARCS) has been operating since October 1996. The TWP ARCS is located on the island of Los Negros, Manus Province, Papua New Guinea, at 2.06°S, 147.42°E.

  3. Options for developing countries in mining development

    SciTech Connect (OSTI)

    Walrond, G.W.; Kumar, R.

    1985-01-01

    This book is a study of the issues that developing countries face in planning and implementing mineral development, taking as case studies Botswana, Sierra Leone, Zambia, Tanzania, Malaysia, Papua New Guinea and the developed states of Quebec and Western Australia. The authors consider the major aspects of the matter including organization and administration; regulation; taxation and surplus distribution; the dynamics of such instruments as royalty, rent resource tax and capital allowances under various cost/price scenarios; and selected mining agreements and their key provisions. They stress throughout the need for foreign investment while maximizing the economic benefits reaped from exhaustible resources.

  4. Annual review of earth and planetary sciences. Vol. 19

    SciTech Connect (OSTI)

    Wetherill, G.W.; Albee, A.L.; Burke, K.C. (Carnegie Inst. of Washington, DC (United States) California Inst. of Tech., Pasadena (United States) National Research Council, Washington, DC (United States))

    1991-01-01

    Various review papers on earth and planetary sciences are presented. The individual topics addressed include: tectonics of the New Guinea area, interpretation of ancient Eolian and dunes, seismic tomography of the earth's mantle, shock modification and chemistry and planetary geologic processes, the significance of evaporites, the magnetosphere, untangling the effects of burial alteration and ancient soil formation. Also discussed are: pressure-temperature-time paths, fractals in rock physics, earthquake prediction, rings in the ocean, applications of Be{minus}10 to problems in the earth sciences, measurement of crustal deformation using the GPS, physics and physical mechanisms of nuclear winter, experiemental determination of bed-form stability.

  5. A 233 km tunnel for lepton and hadron colliders

    SciTech Connect (OSTI)

    Summers, D. J.; Cremaldi, L. M.; Datta, A.; Duraisamy, M.; Luo, T.; Lyons, G. T.

    2012-12-21

    A decade ago, a cost analysis was conducted to bore a 233 km circumference Very Large Hadron Collider (VLHC) tunnel passing through Fermilab. Here we outline implementations of e{sup +}e{sup -}, pp-bar , and {mu}{sup +}{mu}{sup -} collider rings in this tunnel using recent technological innovations. The 240 and 500 GeV e{sup +}e{sup -} colliders employ Crab Waist Crossings, ultra low emittance damped bunches, short vertical IP focal lengths, superconducting RF, and low coercivity, grain oriented silicon steel/concrete dipoles. Some details are also provided for a high luminosity 240 GeV e{sup +}e{sup -} collider and 1.75 TeV muon accelerator in a Fermilab site filler tunnel. The 40 TeV pp-bar collider uses the high intensity Fermilab p-bar source, exploits high cross sections for pp-bar production of high mass states, and uses 2 Tesla ultra low carbon steel/YBCO superconducting magnets run with liquid neon. The 35 TeV muon ring ramps the 2 Tesla superconducting magnets at 9 Hz every 0.4 seconds, uses 250 GV of superconducting RF to accelerate muons from 1.75 to 17.5 TeV in 63 orbits with 71% survival, and mitigates neutrino radiation with phase shifting, roller coaster motion in a FODO lattice.

  6. Approximations of very weak solutions to boundary-value problems.

    SciTech Connect (OSTI)

    Berggren, Martin Olof

    2003-03-01

    Standard weak solutions to the Poisson problem on a bounded domain have square-integrable derivatives, which limits the admissible regularity of inhomogeneous data. The concept of solution may be further weakened in order to define solutions when data is rough, such as for inhomogeneous Dirichlet data that is only square-integrable over the boundary. Such very weak solutions satisfy a nonstandard variational form (u, v) = G(v). A Galerkin approximation combined with an approximation of the right-hand side G defines a finite-element approximation of the very weak solution. Applying conforming linear elements leads to a discrete solution equivalent to the text-book finite-element solution to the Poisson problem in which the boundary data is approximated by L{sub 2}-projections. The L{sub 2} convergence rate of the discrete solution is O(h{sub s}) for some s {element_of} (0,1/2) that depends on the shape of the domain, asserting a polygonal (two-dimensional) or polyhedral (three-dimensional) domain without slits and (only) square-integrable boundary data.

  7. Electric and Gasoline Vehicle Fuel Efficiency Analysis

    Energy Science and Technology Software Center (OSTI)

    1995-05-24

    EAGLES1.1 is PC-based interactive software for analyzing performance (e.g., maximum range) of electric vehicles (EVs) or fuel economy (e.g., miles/gallon) of gasoline vehicles (GVs). The EV model provides a second by second simulation of battery voltage and current for any specified vehicle velocity/time or power/time profile. It takes into account the effects of battery depth-of-discharge (DOD) and regenerative braking. The GV fuel economy model which relates fuel economy, vehicle parameters, and driving cycle characteristics, canmore » be used to investigate the effects of changes in vehicle parameters and driving patterns on fuel economy. For both types of vehicles, effects of heating/cooling loads on vehicle performance can be studied. Alternatively, the software can be used to determine the size of battery needed to satisfy given vehicle mission requirements (e.g., maximum range and driving patterns). Options are available to estimate the time necessary for a vehicle to reach a certain speed with the application of a specified constant power and to compute the fraction of time and/or distance in a drivng cycle for speeds exceeding a given value.« less

  8. Local changes of work function near rough features on Cu surfaces operated under high external electric field

    SciTech Connect (OSTI)

    Djurabekova, Flyura Ruzibaev, Avaz; Parviainen, Stefan; Holmstrm, Eero; Hakala, Mikko

    2013-12-28

    Metal surfaces operated under high electric fields produce sparks even if they are held in ultra high vacuum. In spite of extensive research on the topic of vacuum arcs, the mystery of vacuum arc origin still remains unresolved. The indications that the sparking rates depend on the material motivate the research on surface response to extremely high external electric fields. In this work by means of density-functional theory calculations we analyze the redistribution of electron density on (100) Cu surfaces due to self-adatoms and in presence of high electric fields from ?1?V/nm up to ?2?V/nm (?1 to ?2 GV/m, respectively). We also calculate the partial charge induced by the external field on a single adatom and a cluster of two adatoms in order to obtain reliable information on charge redistribution on surface atoms, which can serve as a benchmarking quantity for the assessment of the electric field effects on metal surfaces by means of molecular dynamics simulations. Furthermore, we investigate the modifications of work function around rough surface features, such as step edges and self-adatoms.

  9. Natural Gas as a Future Fuel for Heavy-Duty Vehicles

    SciTech Connect (OSTI)

    Wai-Lin Litzke; James Wegrzyn

    2001-05-14

    In addition to their significant environmental impacts, medium-duty and heavy-duty (HD) vehicles are high volume fuel users. Development of such vehicles, which include transit buses, refuse trucks, and HD Class 6-8 trucks, that are fueled with natural gas is strategic to market introduction of natural gas vehicles (NGV). Over the past five years the Department of Energy's (DOE) Office of Heavy Vehicle Technologies (OHVT) has funded technological developments in NGV systems to support the growth of this sector in the highly competitive transportation market. The goals are to minimize emissions associated with NGV use, to improve on the economies of scale, and to continue supporting the testing and safety assessments of all new systems. This paper provides an overview of the status of major projects under a program supported by DOE/OHVT and managed by Brookhaven National Laboratory. The discussion focuses on the program's technical strategy in meeting specific goals proposed by the N GV industry and the government. Relevant projects include the development of low-cost fuel storage, fueling infrastructure, and HD vehicle applications.

  10. High Frequency, High Gradient Dielectric Wakefield Acceleration Experiments at SLAC and BNL

    SciTech Connect (OSTI)

    Rosenzweig, James; Travish, Gil; Hogan, Mark; Muggli, Patric; /Southern California U.

    2012-07-05

    Given the recent success of >GV/m dielectric wakefield accelerator (DWA) breakdown experiments at SLAC, and follow-on coherent Cerenkov radiation production at the UCLA Neptune, a UCLA-USC-SLAC collaboration is now implementing a new set of experiments that explore various DWA scenarios. These experiments are motivated by the opportunities presented by the approval of FACET facility at SLAC, as well as unique pulse-train wakefield drivers at BNL. The SLAC experiments permit further exploration of the multi-GeV/m envelope in DWAs, and will entail investigations of novel materials (e.g. CVD diamond) and geometries (Bragg cylindrical structures, slab-symmetric DWAs), and have an over-riding goal of demonstrating >GeV acceleration in {approx}33 cm DWA tubes. In the nearer term before FACET's commissioning, we are planning measurements at the BNL ATF, in which we drive {approx}50-200 MV/m fields with single pulses or pulse trains. These experiments are of high relevance to enhancing linear collider DWA designs, as they will demonstrate potential for efficient operation with pulse trains.

  11. High Frequency, High Gradient Dielectric Wakefield Acceleration Experiments at SLAC and BNL

    SciTech Connect (OSTI)

    Rosenzweig, J. B.; Andonian, G.; Niknejadi, P.; Travish, G.; Williams, O.; Xuan, K.; Muggli, P.; Yakimenko, V.

    2010-11-04

    Given the recent success of >GV/m dielectric wakefield accelerator (DWA) breakdown experiments at SLAC, and follow-on coherent Cerenkov radiation (CCR) production at the UCLA Neptune, a UCLA-USC-SLAC collaboration is now implementing a new set of experiments that explore various DWA scenarios. These experiments are motivated by the opportunities presented by the approval of the FACET facility at SLAC, as well as unique pulse-train wakefield drivers at BNL. The SLAC experiments permit further exploration of the multi-GeV/m envelope in DWAs, and will entail investigations of novel materials (e.g. CVD diamond) and geometries (Bragg cylindrical structures, slab-symmetric DWAs), and have an over-riding goal of demonstrating >GeV acceleration in {approx}33 cm DWA tubes. In the nearer term before FACET's commissioning, we are performing measurements at the BNL ATF, in which we drive {approx}50-200 MV/m fields with single pulses or pulse trains, and observe resonantly driven CCR as well as deflection modes. These experiments are of high relevance to enhancing linear collider DWA designs, as they will demonstrate potential for high efficiency operation with pulse trains, and explore transverse modes for the first time.

  12. Chimeric human parainfluenza virus bearing the Ebola virus glycoprotein as the sole surface protein is immunogenic and highly protective against Ebola virus challenge

    SciTech Connect (OSTI)

    Bukreyev, Alexander Marzi, Andrea; Feldmann, Friederike; Zhang Liqun; Dorward, David W.; Pickles, Raymond J.; Feldmann, Heinz; Collins, Peter L.

    2009-01-20

    We generated a new live-attenuated vaccine against Ebola virus (EBOV) based on a chimeric virus HPIV3/{delta}F-HN/EboGP that contains the EBOV glycoprotein (GP) as the sole transmembrane envelope protein combined with the internal proteins of human parainfluenza virus type 3 (HPIV3). Electron microscopy analysis of the virus particles showed that they have an envelope and surface spikes resembling those of EBOV and a particle size and shape resembling those of HPIV3. When HPIV3/{delta}F-HN/EboGP was inoculated via apical surface of an in vitro model of human ciliated airway epithelium, the virus was released from the apical surface; when applied to basolateral surface, the virus infected basolateral cells but did not spread through the tissue. Following intranasal (IN) inoculation of guinea pigs, scattered infected cells were detected in the lungs by immunohistochemistry, but infectious HPIV3/{delta}F-HN/EboGP could not be recovered from the lungs, blood, or other tissues. Despite the attenuation, the virus was highly immunogenic, and a single IN dose completely protected the animals against a highly lethal intraperitoneal challenge of guinea pig-adapted EBOV.

  13. New hypothesis for formation of Lengguru foldbelt, Irian Jaya, Indonesia

    SciTech Connect (OSTI)

    Dow, D.B.; Robinson, G.P.; Ratman, N.

    1985-02-01

    The Lengguru foldbelt, an area 300 km (180 mi) long with a maximum width of 100 km (60 mi), is near the western end of the island of New Guinea. Sedimentary rocks of the belt include Mesozoic marine sandstone and shale, Tertiary deep-water limestone, Tertiary shelf limestone, and upper Miocene to Pleistocene detritus. The slab of folded platform sedimentary rocks making up the Lengguru foldbelt was originally at the northern margin of the Australian continent and was thrust southwestward over the undeformed continental crust of the western part of New Guinea. The slab was also rotated clockwise by about 30/sup 0/ about a pivot at its northern end. During rotation, thrusting and decollement within the foldbelt caused a repetition by stacking of the stratigraphic section, and the belt was dragged along transcurrent faults to the south. This foldbelt is of interest for oil exploration because of proximity to the Salawati and Bintuni oil fields on the westernmost tip of the island.

  14. C-Band Scanning ARM Precipitation Radar (C-SAPR) Handbook

    SciTech Connect (OSTI)

    Widener, K; Bharadwaj, N

    2012-11-13

    The C-band scanning ARM precipitation radar (C-SAPR) is a scanning polarimetric Doppler radar transmitting simultaneously in both H and V polarizations. With a 350-kW magnetron transmitter, this puts 125 kW of transmitted power for each polarization. The receiver for the C-SAPR is a National Center for Atmospheric Research (NCAR) -developed Hi-Q system operating in a coherent-on-receive mode. The ARM Climate Research Facility operates two C-SAPRs; one of them is deployed near the Southern Great Plains (SGP) Central Facility near the triangular array of X-SAPRs, and the second C-SAPR is deployed at ARM’s Tropical Western Pacific (TWP) site on Manus Island in Papua New Guinea.

  15. Reconstruction of deglacial sea surface temperature in the tropical Pacific from selective analysis of a fossil coral

    SciTech Connect (OSTI)

    Allison, N.; Finch, A.A.; Tudhope, A.W.; Newville, M.; Sutton, S.R.; Ellam, R.M.

    2010-07-13

    The Sr/Ca of coral skeletons demonstrates potential as an indicator of sea surface temperatures (SSTs). However, the glacial-interglacial SST ranges predicted from Sr/Ca of fossil corals are usually higher than from other marine proxies. We observed infilling of secondary aragonite, characterized by high Sr/Ca ratios, along intraskeletal pores of a fossil coral from Papua New Guinea that grew during the penultimate deglaciation (130 {+-} 2 ka). Selective microanalysis of unaltered areas of the fossil coral indicates that SSTs at {approx}130 ka were {le} 1 C cooler than at present in contrast with bulk measurements (combining infilled and unaltered areas) which indicate a difference of 6-7 C. The analysis of unaltered areas of fossil skeletons by microprobe techniques may offer a route to more accurate reconstruction of past SSTs.

  16. Complete genome sequence of Hippea maritima type strain (MH2T)

    SciTech Connect (OSTI)

    Huntemann, Marcel; Lu, Megan; Nolan, Matt; Lapidus, Alla L.; Lucas, Susan; Hammon, Nancy; Deshpande, Shweta; Cheng, Jan-Fang; Tapia, Roxanne; Han, Cliff; Goodwin, Lynne A.; Pitluck, Sam; Liolios, Konstantinos; Pagani, Ioanna; Ivanova, N; Ovchinnikova, Galina; Pati, Amrita; Chen, Amy; Palaniappan, Krishna; Land, Miriam L; Hauser, Loren John; Jeffries, Cynthia; Detter, J. Chris; Brambilla, Evelyne-Marie; Rohde, Manfred; Spring, Stefan; Goker, Markus; Woyke, Tanja; Bristow, James; Eisen, Jonathan; Markowitz, Victor; Hugenholtz, Philip; Kyrpides, Nikos C; Klenk, Hans-Peter; Mavromatis, K

    2011-01-01

    Hippea maritima (Miroshnichenko et al. 1999) is the type species of the genus Hippea, which belongs to the family Desulfurellaceae within the class Deltaproteobacteria. The anaerobic, moderately thermophilic marine sulfur-reducer was first isolated from shallow-water hot vents in Matipur Harbor, Papua New Guinea. H. maritima was of interest for genome se- quencing because of its isolated phylogenetic location, as a distant next neighbor of the ge- nus Desulfurella. Strain MH2T is the first type strain from the order Desulfurellales with a com- pletely sequenced genome. The 1,694,430 bp long linear genome with its 1,723 protein- coding and 57 RNA genes consists of one circular chromosome and is a part of the Genomic Encyclopedia of Bacteria and Archaea project.

  17. 1-D seismic velocity model and hypocenter relocation using double difference method around West Papua region

    SciTech Connect (OSTI)

    Sabtaji, Agung E-mail: agung.sabtaji@bmkg.go.id; Nugraha, Andri Dian

    2015-04-24

    West Papua region has fairly high of seismicity activities due to tectonic setting and many inland faults. In addition, the region has a unique and complex tectonic conditions and this situation lead to high potency of seismic hazard in the region. The precise earthquake hypocenter location is very important, which could provide high quality of earthquake parameter information and the subsurface structure in this region to the society. We conducted 1-D P-wave velocity using earthquake data catalog from BMKG for April, 2009 up to March, 2014 around West Papua region. The obtained 1-D seismic velocity then was used as input for improving hypocenter location using double-difference method. The relocated hypocenter location shows fairly clearly the pattern of intraslab earthquake beneath New Guinea Trench (NGT). The relocated hypocenters related to the inland fault are also observed more focus in location around the fault.

  18. The effects of repeated low-dose sarin exposure

    SciTech Connect (OSTI)

    Shih, T.-M. . E-mail: tsungming.a.shih@us.army.mil; Hulet, S.W.; McDonough, J.H.

    2006-09-01

    This project assessed the effects of repeated low-dose exposure of guinea pigs to the organophosphorus nerve agent sarin. Animals were injected once a day, 5 days per week (Monday-Friday), for 2 weeks with fractions (0.3x, 0.4x, 0.5x, or 0.6x) of the established LD{sub 5} dose of sarin (42 {mu}g/kg, s.c.). The animals were assessed for changes in body weight, red blood cell (RBC) acetylcholinesterase (AChE) levels, neurobehavioral reactions to a functional observational battery (FOB), cortical electroencephalographic (EEG) power spectrum, and intrinsic acetylcholine (ACh) neurotransmitter (NT) regulation over the 2 weeks of sarin exposure and for up to 12 days postinjection. No guinea pig receiving 0.3, 0.4 or 0.5 x LD{sub 5} of sarin showed signs of cortical EEG seizures despite decreases in RBC AChE levels to as low as 10% of baseline, while seizures were evident in animals receiving 0.6 x LD{sub 5} of sarin as early as the second day; subsequent injections led to incapacitation and death. Animals receiving 0.5 x LD{sub 5} sarin showed obvious signs of cholinergic toxicity; overall, 2 of 13 animals receiving 0.5 x LD{sub 5} sarin died before all 10 injections were given, and there was a significant increase in the angle of gait in the animals that lived. By the 10th day of injection, the animals receiving saline were significantly easier to remove from their cages and handle and significantly less responsive to an approaching pencil and touch on the rump in comparison with the first day of testing. In contrast, the animals receiving 0.4 x LD{sub 5} sarin failed to show any significant reductions in their responses to an approaching pencil and a touch on the rump as compared with the first day. The 0.5 x LD{sub 5} sarin animals also failed to show any significant changes to the approach and touch responses and did not adjust to handling or removal from the cage from the first day of injections to the last day of handling. Thus, the guinea pigs receiving the 0.4 and 0.5 x LD{sub 5} doses of sarin failed to habituate to some aspects of neurobehavioral testing. Spectral analysis of EEG data suggested that repeated sarin exposure may disrupt normal sleeping patterns (i.e., lower frequency bandwidths). While these EEG changes returned to relative normalcy 6 days after the last injection in animals receiving 0.4 x LD{sub 5} sarin, these changes were still observed in the animals that received 0.5 x LD{sub 5} sarin. Ten to twelve days after the last sarin injection (in 0.4 x LD{sub 5} group only), neurochemical data showed that striatal choline levels were reduced in comparison to the saline group. At this time, atropine sulfate (5 mg/kg, i.p.) challenge resulted in a transient elevation in striatal ACh levels in animals exposed to repeated 0.4 x LD{sub 5} sarin as well as in control animals. No evidence of brain or heart pathology was found in any guinea pig that survived all 10 sarin injections.

  19. PowerPoint Presentation

    U.S. Energy Information Administration (EIA) Indexed Site

    LNG World LNG Imports 1964 - 2007 World LNG Imports 1964 - 2007 0 20 40 60 80 100 120 140 160 180 200 1964 1968 1972 1976 1980 1984 1988 1992 1996 2000 2004 Americas Total Europe Total Asia in mtpa 7.7%pa 2 LNG 0 4 8 12 16 1 9 6 8 1 9 7 3 1 9 7 8 1 9 8 3 1 9 8 8 1 9 9 3 1 9 9 8 2 0 0 3 Algeria Trinidad Egypt Nigeria Eq. Guinea M. East Pacific Basin in mtpa US LNG Imports by Source 1968-2007 US LNG Imports by Source 1968-2007 3 LNG Regional LNG Production 1990 - 2007 Regional LNG Production 1990

  20. Darwin : The Third DOE ARM TWP ARCS Site /

    SciTech Connect (OSTI)

    Clements, William E.; Jones, L. A.; Baldwin, T.; Nitschke, K.

    2002-01-01

    The United States Department of Energy's (DOE) Atmospheric Radiation Measurement (ARM) Program began operations in its Tropical Western Pacific (TWP) locale in October 1996 when the first Atmospheric Radiation and Cloud Station (ARCS) began collecting data on Manus Island in Papua New Guinea (PNG). Two years later, in November 1998, a second ARCS began operations on the island of Nauru in the Central Pacific. Now a third ARCS has begun collecting data in Darwin, Australia. The Manus, Nauru, and Darwin sites are operated through collaborative agreements with the PNG National Weather Service, The Nauru Department of Industry and Economic Development (IED), and the Australian Bureau of Meteorology's (BOM) Special Services Unit (SSU) respectively. All ARM TWP activities in the region are coordinated with the South Pacific Regional Environment Programme (SPREP) based in Apia, Samoa. The Darwin ARM site and its role in the ARM TWP Program are discussed.

  1. Atmospheric Radiation Measurement Program facilities newsletter, May 2000.

    SciTech Connect (OSTI)

    Sisterson, D.L.

    2000-06-01

    This month the authors will visit an ARM CART site with a pleasant climate: the Tropical Western Pacific (TWP) CART site, along the equator in the western Pacific Ocean. The TWP locale lies between 10 degrees North latitude and 10 degrees South latitude and extends from Indonesia east-ward beyond the international date line. This area was selected because it is in and around the Pacific warm pool, the area of warm sea-surface temperatures that determine El Nino/La Nina episodes. The warm pool also adds heat and moisture to the atmosphere and thus fuels cloud formation. Understanding the way tropical clouds and water vapor affect the solar radiation budget is a focus of the ARM Program. The two current island-based CART sites in the TWP are in Manus Province in Papua New Guinea and on Nauru Island.

  2. Hazardous waste management in the Pacific basin

    SciTech Connect (OSTI)

    Cirillo, R.R.; Chiu, S.; Chun, K.C.; Conzelmann, G.; Carpenter, R.A.; Indriyanto, S.H.

    1994-11-01

    Hazardous waste control activities in Asia and the Pacific have been reviewed. The review includes China (mainland, Hong Kong, and Taiwan), Indonesia, Korea, Malaysia, Papua New Guinea, the Philippines, Singapore, and Thailand. It covers the sources of hazardous waste, the government structure for dealing with hazardous waste, and current hazardous waste control activities in each country. In addition, the hazardous waste program activities of US government agencies, US private-sector organizations, and international organizations are reviewed. The objective of these reviews is to provide a comprehensive picture of the current hazardous waste problems and the waste management approaches being used to address them so that new program activities can be designed more efficiently.

  3. Australia/Pacific: Industry watchers expect the worst

    SciTech Connect (OSTI)

    Not Available

    1986-08-01

    This article presents the outlook for the Australia/Pacific area with respect to petroleum. The main observations are: ATEA forsees Australia drilling declining by nearly 50% this year compared to last; With no tax relief in sight for crude, major Aussie oil projects are delayed; New Zealand's leasing moratorium has ended, and licensing policies have improved; Australia's self-sufficiency dream vanishes as Bass Strait exports dwindle; Gulf has more finds onshore Papua/New Guinea, but well economics still questionable; Australian gas projects enjoy some insulation from poor crude markets; Jabiru find in Timor Sea due onstream, and Northwest Shelf LNG export plans continue; Australia's largest operators each announce budget cuts; rig count continues to plunge.

  4. Africa: the emphasis is exploration

    SciTech Connect (OSTI)

    Not Available

    1980-08-15

    Individual country reports on drilling, oil and gas production, and petroleum exploration and reserves are given for Africa. Nigeria was the continent's largest oil producer in 1979, averaging 2.3 million bpd, followed closely by Libya with 2.07 million bpd. Algeria cut production of crude oil in 1979 to a level of 1,194,350 bpd, and increased gas production to 2031 mmcfd. In Egypt, the return of Israeli-occupied oil fields and a surge in productive capacity enabled production averaging 524,000 bpd. Brief country reports are included for Gabon, Angola, Republic of the Congo, Cameroun, Tunisia, Morocco, Zaire, Ivory Coast, Ghana, Niger, Chad, Republic of South Africa, Sudan, Tanzania, Equatorial Guinea, Seychelles Islands, Mauritania, Republic of Mali, Benin, Kenya, Madagascar, Botswana, Gambia, Mozambique, and Senegal.

  5. New Developments in the Theory of HTSC [High Temperature Superconductors

    DOE R&D Accomplishments [OSTI]

    Abrikosov, A.A.

    1994-09-01

    The superconductor is supposed to consist of alternating layers of two kinds: (1) layers with an attractive electron interaction and an effective mass of usual magnitude, (2) layers without interaction and with a large effective mass. The overlap between the layers is assumed to be small, its energy, t, being much less than {Delta}. It is shown, that such a model explains the most peculiar property found in experiments on electronic Raman light scattering in BSCCO 2212: different threshold values for the Raman satellite measured at two different polarizations of the incident and scattered light. The tunneling conductance G(V)= dJ/dV is analyzed for the same model. In order to fit the qualitative features of experimental data, it is assumed that the tunneling probability to the normal layers is much less, than to the superconducting layers. The conductance is calculated for the case t{much_lt}{Delta}. A brief analysis is given for the case t{approximately}{Delta}, which proves that such an assumption definitely contradicts the experimental data for BSCCO. The possible nature of the electronic states in the normal layers is discussed. In connection with the experimental discovery (angle resolved photoemission spectroscopy, ARPES) of the extended saddle point singularities in the electron spectrum of a variety of HTSC consequences are derived for T{sub c} and {Delta} in a simple model. A large enhancement of superconductivity is possible if the singularity has a sufficient extension and is located close to the Fermi energy. In order to explain the anisotropy of the energy gap, observed in ARPES experiments, on the basis of the "extended saddle point singularities" an assumption is done that the Coulomb interactions are weakly screened, i.e. the Debye screening radius is much larger than the lattice period; this makes the electron interaction long ranged (E-L model).

  6. Corotating solar wind structures and recurrent trains of enhanced diurnal variation in galactic cosmic rays

    SciTech Connect (OSTI)

    Yeeram, T.; Ruffolo, D.; Siz, A.; Kamyan, N.; Nutaro, T. E-mail: david.ruf@mahidol.ac.th E-mail: p_chang24@hotmail.com

    2014-04-01

    Data from the Princess Sirindhorn Neutron Monitor at Doi Inthanon, Thailand, with a vertical cutoff rigidity of 16.8 GV, were utilized to determine the diurnal anisotropy (DA) of Galactic cosmic rays (GCRs) near Earth during solar minimum conditions between 2007 November and 2010 November. We identified trains of enhanced DA over several days, which often recur after a solar rotation period (?27 days). By investigating solar coronal holes as identified from synoptic maps and solar wind parameters, we found that the intensity and anisotropy of cosmic rays are associated with the high-speed streams (HSSs) in the solar wind, which are in turn related to the structure and evolution of coronal holes. An enhanced DA was observed after the onset of some, but not all, HSSs. During time periods of recurrent trains, the DA was often enhanced or suppressed according to the sign of the interplanetary magnetic field B, which suggests a contribution from a mechanism involving a southward gradient in the GCR density, n, and a gradient anisotropy along B ?n. In one non-recurrent and one recurrent sequence, an HSS from an equatorial coronal hole was merged with that from a trailing mid-latitude extension of a polar coronal hole, and the slanted HSS structure in space with suppressed GCR density can account for the southward GCR gradient. We conclude that the gradient anisotropy is a source of temporary changes in the GCR DA under solar minimum conditions, and that the latitudinal GCR gradient can sometimes be explained by the coronal hole morphology.

  7. Constraints on particle dark matter from cosmic-ray antiprotons

    SciTech Connect (OSTI)

    Fornengo, N.; Vittino, A.; Maccione, L. E-mail: luca.maccione@lmu.de

    2014-04-01

    Cosmic-ray antiprotons represent an important channel for dark matter indirect-detection studies. Current measurements of the antiproton flux at the top of the atmosphere and theoretical determinations of the secondary antiproton production in the Galaxy are in good agreement, with no manifest deviation which could point to an exotic contribution in this channel. Therefore, antiprotons can be used as a powerful tool for constraining particle dark matter properties. By using the spectrum of PAMELA data from 50 MV to 180 GV in rigidity, we derive bounds on the dark matter annihilation cross section (or decay rate, for decaying dark matter) for the whole spectrum of dark matter annihilation (decay) channels and under different hypotheses of cosmic-rays transport in the Galaxy and in the heliosphere. For typical models of galactic propagation, the constraints are strong, setting a lower bound on the dark matter mass of a ''thermal'' relic at about 40–80 GeV for hadronic annihilation channels. These bounds are enhanced to about 150 GeV on the dark matter mass, when large cosmic-rays confinement volumes in the Galaxy are considered, and are reduced to 3–4 GeV for annihilation to light quarks (no bound for heavy-quark production) when the confinement volume is small. Bounds for dark matter lighter than few tens of GeV are due to the low energy part of the PAMELA spectrum, an energy region where solar modulation is relevant: to this aim, we have implemented a detailed solution of the transport equation in the heliosphere, which allowed us not only to extend bounds to light dark matter, but also to determine the uncertainty on the constraints arising from solar modulation modelling. Finally, we estimate the impact of soon-to-come AMS-02 data on the antiproton constraints.

  8. Romania: Brand-New Engineering Solutions

    SciTech Connect (OSTI)

    Ken Allen; Lucian Biro; Nicolae Zamfir; Madalina Budu

    2011-01-01

    The HEU spent nuclear fuel transport from Romania was a pilot project in the framework of the Russian Research Reactor Fuel Return Program (RRRFR), being the first fully certified spent nuclear fuel shipment by air. The successful implementation of the Romanian shipment also brought various new technology in the program, further used by other participating countries. Until 2009, the RRRFR program repatriated to the Russian Federation HEU spent nuclear fuel of Russian origin from many countries, like Uzbekistan, Czech Republic, Latvia, Hungary, Kazakhstan and Bulgaria. The means of transport used were various; from specialized TK-5 train for the carriage of Russian TUK-19 transport casks, to platform trains for 20 ft freight ISO containers carrying Czech Skoda VPVR/M casks; from river barge on the Danube, to vessel on the Mediterranean Sea and Atlantic Ocean. Initially, in 2005, the transport plan of the HEU spent nuclear fuel from the National Institute for R&D in Nuclear Physics and Nuclear Engineering 'Horia Hulubei' in Magurele, Romania considered a similar scheme, using the specialized TK-5 train transiting Ukraine to the destination point in the Russian Federation, or, as an alternative, using the means and route of the spent nuclear fuel periodically shipped from the Bulgarian nuclear power plant Kosloduy (by barge on the Danube, and by train through Ukraine to the Russian Federation). Due to impossibility to reach an agreement in due time with the transit country, in February 2007 the US, Russian and Romanian project partners decided to adopt the air shipment of the spent nuclear fuel as prime option, eliminating the need for agreements with any transit countries. By this time the spent nuclear fuel inspections were completed, proving the compliance of the burn-up parameters with the international requirements for air shipments of radioactive materials. The short air route avoiding overflying of any other countries except the country of origin and the country of destination also contributed to the decision making in this issue. The efficient project management and cooperation between the three countries (Russia, Romania and USA) made possible, after two and a half years of preparation work, for the first fully certified spent nuclear fuel air shipment to take place on 29th of June 2009, from Romanian airport 'Henri Coanda' to the Russian airport 'Koltsovo' near Yekaterinburg. One day before that, after a record period of 3 weeks of preparation, another HEU cargo was shipped by air from Romanian Institute for Nuclear Research in Pitesti to Russia, containing fresh pellets and therefore making Romania the third HEU-free country in the RRRFR program.

  9. Midlatitude Continental Convective Clouds Experiment (MC3E)

    SciTech Connect (OSTI)

    Jensen, MP; Petersen, WA; Del Genio, AD; Giangrande, SE; Heymsfield, A; Heymsfield, G; Hou, AY; Kollias, P; Orr, B; Rutledge, SA; Schwaller, MR; Zipser, E

    2010-04-01

    Convective processes play a critical role in the Earths energy balance through the redistribution of heat and moisture in the atmosphere and subsequent impacts on the hydrologic cycle. Global observation and accurate representation of these processes in numerical models is vital to improving our current understanding and future simulations of Earths climate system. Despite improvements in computing power, current operational weather and global climate models are unable to resolve the natural temporal and spatial scales that are associated with convective and stratiform precipitation processes; therefore, they must turn to parameterization schemes to represent these processes. In turn, the physical basis for these parameterization schemes needs to be evaluated for general application under a variety of atmospheric conditions. Analogously, space-based remote sensing algorithms designed to retrieve related cloud and precipitation information for use in hydrological, climate, and numerical weather prediction applications often rely on physical parameterizations that reliably translate indirectly related instrument measurements to the physical quantity of interest (e.g., precipitation rate). Importantly, both spaceborne retrieval algorithms and model convective parameterization schemes traditionally rely on field campaign data sets as a basis for evaluating and improving the physics of their respective approaches. The Midlatitude Continental Convective Clouds Experiment (MC3E) will take place in central Oklahoma during the AprilMay 2011 period. The experiment is a collaborative effort between the U.S. Department of Energy (DOE) Atmospheric Radiation Measurement (ARM) Climate Research Facility and the National Aeronautics and Space Administrations (NASA) Global Precipitation Measurement (GPM) mission Ground Validation (GV) program. The field campaign leverages the unprecedented observing infrastructure currently available in the central United States, combined with an extensive sounding array, remote sensing and in situ aircraft observations, NASA GPM ground validation remote sensors, and new ARM instrumentation purchased with American Recovery and Reinvestment Act funding. The overarching goal is to provide the most complete characterization of convective cloud systems, precipitation, and the environment that has ever been obtained, providing constraints for model cumulus parameterizations and space-based rainfall retrieval algorithms over land that have never before been available. Several different components of convective cloud and precipitation processes tangible to both the convective parameterization and precipitation retrieval algorithm problem are targeted, such as preconvective environment and convective initiation, updraft/downdraft dynamics, condensate transport and detrainment, precipitation and cloud microphysics, spatial and temporal variability of precipitation, influence on the environment and radiation, and a detailed description of the large-scale forcing.

  10. Acute alteration of cardiac ECG, action potential, I{sub Kr} and the human ether-a-go-go-related gene (hERG) K{sup +} channel by PCB 126 and PCB 77

    SciTech Connect (OSTI)

    Park, Mi-Hyeong; Park, Won Sun; Jo, Su-Hyun

    2012-07-01

    Polychlorinated biphenyls (PCBs) have been known as serious persistent organic pollutants (POPs), causing developmental delays and motor dysfunction. We have investigated the effects of two PCB congeners, 3,3′,4,4′-tetrachlorobiphenyl (PCB 77) and 3,3′,4,4′,5-pentachlorobiphenyl (PCB 126) on ECG, action potential, and the rapidly activating delayed rectifier K{sup +} current (I{sub Kr}) of guinea pigs' hearts, and hERG K{sup +} current expressed in Xenopus oocytes. PCB 126 shortened the corrected QT interval (QTc) of ECG and decreased the action potential duration at 90% (APD{sub 90}), and 50% of repolarization (APD{sub 50}) (P < 0.05) without changing the action potential duration at 20% (APD{sub 20}). PCB 77 decreased APD{sub 20} (P < 0.05) without affecting QTc, APD{sub 90}, and APD{sub 50}. The PCB 126 increased the I{sub Kr} in guinea-pig ventricular myocytes held at 36 °C and hERG K{sup +} current amplitude at the end of the voltage steps in voltage-dependent mode (P < 0.05); however, PCB 77 did not change the hERG K{sup +} current amplitude. The PCB 77 increased the diastolic Ca{sup 2+} and decreased Ca{sup 2+} transient amplitude (P < 0.05), however PCB 126 did not change. The results suggest that PCB 126 shortened the QTc and decreased the APD{sub 90} possibly by increasing I{sub Kr}, while PCB 77 decreased the APD{sub 20} possibly by other modulation related with intracellular Ca{sup 2+}. The present data indicate that the environmental toxicants, PCBs, can acutely affect cardiac electrophysiology including ECG, action potential, intracellular Ca{sup 2+}, and channel activity, resulting in toxic effects on the cardiac function in view of the possible accumulation of the PCBs in human body. -- Highlights: ► PCBs are known as serious environmental pollutants and developmental disruptors. ► PCB 126 shortened QT interval of ECG and action potential duration. ► PCB 126 increased human ether-a-go-go-related K{sup +} current and I{sub Kr}. ► PCB 77 decreased action potential duration and increased intracellular Ca{sup 2+} content. ► PCBs acutely change cardiac electrophysiology and rhythmicity.

  11. The Gut Microbiota of Rural Papua New Guineans: Composition, Diversity Patterns, and Ecological Processes

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Martínez, Inés; Stegen, James C.; Maldonado-Gómez, Maria X.; Eren, A. Murat; Siba, Peter M.; Greenhill, Andrew R.; Walter, Jens

    2015-04-01

    Comparisons between the fecal microbiota of humans from industrialized and non-industrialized communities indicate a pronounced impact of westernization on the diversity and composition of the human gut microbiota. However, the exact consequences of westernization on community characteristics are still insufficiently understood, and the ecological processes that drive differences have not been elucidated. Here we have compared the fecal microbiota of adults from two non-industrialized regions in Papua New Guinea (PNG) with that of United States (US) residents. Papua New Guineans harbor communities with greater bacterial diversity but lower inter-individual variation. Although the fecal microbiota in PNG and US was largelymore » dominated by shared bacterial lineages, the relative abundance of 25 families, 45 genera, and 230 species-level OTUs differed, and 47 core OTUs in PNG were undetectable in US residents. To gain insight into the ecological mechanisms that cause the observed differences, we quantified community assembly processes in PNG and US microbiomes using a null modeling approach. This analysis demonstrated a significant higher rate of bacterial dispersal in PNG and divergent selective environments in the US. Interestingly, equivalent findings were obtained for other datasets comparing industrialized and non-industrialized microbiomes. Overall, the findings demonstrate a dominant role for microbial dispersal in shaping the human gut microbiota in non-industrialized societies, and point to differential selection pressures across individuals as a major factor shaping microbiomes associated with modern lifestyle.« less

  12. Cloud Classes and Radiative Heating profiles at the Manus and Nauru Atmospheric Radiation Measurement (ARM) Sites

    SciTech Connect (OSTI)

    Mather, James H.; McFarlane, Sally A.

    2009-10-07

    The Tropical Western Pacific (TWP) is a convective regime; however, the frequency and depth of convection is dependant on dynamical forcing which exhibits variability on a range of temporal scales and also on location within the region. Manus Island, Papua New Guinea lies in the heart of the western Pacific warm pool region and exhibits frequent deep convection much of the time while Nauru, which lies approximately 20 degrees to the East of Manus, lies in a transition zone where the frequency of convection is dependent on the phase of the El Nino/Southern Oscillation. Because of this difference in dynamical regime, the distribution of clouds and the associated radiative heating is quite different at the two sites. Individual cloud types: boundary layer cumulus, thin cirrus, stratiform convective outflow, do occur at both sites – but with different frequencies. In this study we compare cloud profiles and heating profiles for specific cloud types at these two sites using data from the Atmospheric Radiation Measurement (ARM) Climate Research Facility (ACRF). Results of this comparison indicate that, while the frequency of specific cloud types differ between the two sites as one would expect, the characteristics of individual cloud classes are remarkably similar. This information could prove to be very useful for applying tropical ARM data to the broader region.

  13. Seismic hazard analysis for Jayapura city, Papua

    SciTech Connect (OSTI)

    Robiana, R. Cipta, A.

    2015-04-24

    Jayapura city had destructive earthquake which occurred on June 25, 1976 with the maximum intensity VII MMI scale. Probabilistic methods are used to determine the earthquake hazard by considering all possible earthquakes that can occur in this region. Earthquake source models using three types of source models are subduction model; comes from the New Guinea Trench subduction zone (North Papuan Thrust), fault models; derived from fault Yapen, TareraAiduna, Wamena, Memberamo, Waipago, Jayapura, and Jayawijaya, and 7 background models to accommodate unknown earthquakes. Amplification factor using geomorphological approaches are corrected by the measurement data. This data is related to rock type and depth of soft soil. Site class in Jayapura city can be grouped into classes B, C, D and E, with the amplification between 0.5 – 6. Hazard maps are presented with a 10% probability of earthquake occurrence within a period of 500 years for the dominant periods of 0.0, 0.2, and 1.0 seconds.

  14. ARM Research in the Equatorial Western Pacific: A Decade and Counting

    SciTech Connect (OSTI)

    Long, Charles N.; McFarlane, Sally A.; Del Genio, Anthony D.; Minnis, Patrick; Ackerman, Thomas P.; Mather, James H.; Comstock, Jennifer M.; Mace, Gerald G.; Jensen, Michael; Jakob, Christian

    2013-05-22

    The tropical western Pacific (TWP) is an important climatic region. Strong solar heating, warm sea surface temperatures and the annual progression of the Intertropical Convergence Zone (ITCZ) across this region generate abundant convective systems, which through their effects on the heat and water budgets have a profound impact on global climate and precipitation. To accurately represent tropical cloud systems in models, measurements of tropical clouds, the environment in which they reside, and their impact on the radiation and water budgets are needed. Because of the remote location, ground-based datasets of cloud, atmosphere, and radiation properties from the TWP region have traditionally come primarily from short-term field experiments. While providing extremely useful information on physical processes, these datasets are limited in statistical and climatological information because of their short duration. To provide long-term measurements of the surface radiation budget in the tropics, and the atmospheric properties that affect it, the Atmospheric Radiation Measurement program established a measurement site on Manus Island, Papua New Guinea in 1996 and on the island republic of Nauru in late 1998. These sites provide unique datasets available from more than 10 years of operation in the equatorial western Pacific on Manus and Nauru. We present examples of the scientific use of these datasets including characterization of cloud properties, analysis of cloud radiative forcing, model studies of tropical clouds and processes, and validation of satellite algorithms. We also note new instrumentation recently installed at the Manus site that will expand opportunities for tropical atmospheric science.

  15. Characteristics Associated with the Madden-Julian Oscillation at Manus Island

    SciTech Connect (OSTI)

    Deng, Liping; McFarlane, Sally A.; Flaherty, Julia E.

    2013-05-15

    Ground-based high temporal and vertical resolution datasets from 2002 to 2008 of observations at the Atmospheric Radiation Measurement (ARM) Tropical Western Pacific (TWP) site on Manus Island, Papua New Guinea are used to examine the evolution of clouds and rainfall associated with the MJO life cycle. A composite MJO event is developed based on the NOAA MJO Index 4 using 13 events. The analysis shows that the cloud evolution during the composited MJO life cycle depicts a two-phase structure consisting of a development phase and a mature phase. During the development phase, congestus is the most important cloud type; during the mature phase, deep convection is the dominant cloud type. Consistent with this two-phase structure, the heavy rainfall frequency also shows a two-peak structure during the MJO life cycle. Light rainfall does not show a clear relation to the MJO life cycle, but shows variability on shorter time scales. From the development phase to the mature phase, the MJO structure shifts from the Type I to Type II structure, showing a different phase relationship between convection and dynamic fields (or wave motion) in the development and mature phases. During the shift, mid-level clouds play an important role in moving moisture to the mid-troposphere and preparing the atmosphere for the following deep convection. The discharge-recharge theory explains some of observed features of the MJO evolution at the ARM TWP Manus Island site.

  16. Human radiation experiments associated with the US Department of Energy and its predecessors

    SciTech Connect (OSTI)

    1995-07-01

    This document contains a listing, description, and selected references for documented human radiation experiments sponsored, supported, or performed by the US Department of Energy (DOE) or its predecessors, including the US Energy Research and Development Administration (ERDA), the US Atomic Energy Commission (AEC), the Manhattan Engineer District (MED), and the Off ice of Scientific Research and Development (OSRD). The list represents work completed by DOE`s Off ice of Human Radiation Experiments (OHRE) through June 1995. The experiment list is available on the Internet via a Home Page on the World Wide Web (http://www.ohre.doe.gov). The Home Page also includes the full text of Human Radiation Experiments. The Department of Energy Roadmap to the Story and the Records (DOE/EH-0445), published in February 1995, to which this publication is a supplement. This list includes experiments released at Secretary O`Leary`s June 1994 press conference, as well as additional studies identified during the 12 months that followed. Cross-references are provided for experiments originally released at the press conference; for experiments released as part of The DOE Roadmap; and for experiments published in the 1986 congressional report entitled American Nuclear Guinea Pigs: Three Decades of Radiation Experiments on US Citizens. An appendix of radiation terms is also provided.

  17. Quantification of the epitope diversity of HIV-1-specific binding antibodies by peptide microarrays for global HIV-1 vaccine development

    SciTech Connect (OSTI)

    Stephenson, Kathryn E.; Neubauer, George H.; Reimer, Ulf; Pawlowski, Nikolaus; Knaute, Tobias; Zerweck, Johannes; Korber, Bette T.; Barouch, Dan H.

    2014-11-14

    An effective vaccine against human immunodeficiency virus type 1 (HIV-1) will have to provide protection against a vast array of different HIV-1 strains. Current methods to measure HIV-1-specific binding antibodies following immunization typically focus on determining the magnitude of antibody responses, but the epitope diversity of antibody responses has remained largely unexplored. Here we describe the development of a global HIV-1 peptide microarray that contains 6564 peptides from across the HIV-1 proteome and covers the majority of HIV-1 sequences in the Los Alamos National Laboratory global HIV-1 sequence database. Using this microarray, we quantified the magnitude, breadth, and depth of IgG binding to linear HIV-1 sequences in HIV-1-infected humans and HIV-1-vaccinated humans, rhesus monkeys and guinea pigs. The microarray measured potentially important differences in antibody epitope diversity, particularly regarding the depth of epitope variants recognized at each binding site. Our data suggest that the global HIV-1 peptide microarray may be a useful tool for both preclinical and clinical HIV-1 research.

  18. Challenge for Mesozoic hydrocarbon exploration in the Eastern Indonesia

    SciTech Connect (OSTI)

    Abdullah, S.; Rukmiati, M.G.; Sitompul, N.

    1996-12-31

    The eastern part of Indonesia covers approximately 3 million square kilometers, 35 percent being landmass and 65 percent covered by ocean. Only three of 38 sedimentary basins are producing hydrocarbon (Salawati, Bintuni, and Seram Basins). Oil and gas have discovered in the Lariang, Bone, Timor, Banggai, Sula and Biak Basins, however the discoveries have not developed yet. Hydrocarbon systems in Northern Australia and Papua New Guinea give the major contributions to the geological idea of Pre-Tertiary section in the less explored area in the Eastern Indonesia. The Triassic-Middle Jurassic marine carbonaceous shale sequences are the main hydrocarbon source rock in the Irian Jaya and surrounding area (Buton, gula and Seram basins). The main Mesozoic reservoir are the Kembelangan Formation in the Bintuni Basin of Irian Jaya and Bobong Formation in the North Sula Region. Exploration play types in the Eastern Indonesia can be divided into five types: 1 - Peri Cratonic, 2 - Marginal Rift Graben, 3 - Thrust Fold Belt Island Arc, 4 - Early Collision and 5 -Microcontinental Block - Advanced Collision. Recent discoveries through Mesozoic section in Eastern Indonesia are: Roabiba-1 (1990) in Bintuni Basin-Irian Jaya (Kambelangan Formation); Loku- 1 (1990) in North Sula region (Pre-Tertiary sediments); Oseil-1 (1993/94) in Bula-Seram Basin (Jurassic Manusela Formation); Elang-1 (1 994); Kakaktua-1 (1994) and Laminaria-1 in North Bonaparte Basin (Upper Jurassic Sands).

  19. Challenge for Mesozoic hydrocarbon exploration in the Eastern Indonesia

    SciTech Connect (OSTI)

    Abdullah, S.; Rukmiati, M.G.; Sitompul, N. )

    1996-01-01

    The eastern part of Indonesia covers approximately 3 million square kilometers, 35 percent being landmass and 65 percent covered by ocean. Only three of 38 sedimentary basins are producing hydrocarbon (Salawati, Bintuni, and Seram Basins). Oil and gas have discovered in the Lariang, Bone, Timor, Banggai, Sula and Biak Basins, however the discoveries have not developed yet. Hydrocarbon systems in Northern Australia and Papua New Guinea give the major contributions to the geological idea of Pre-Tertiary section in the less explored area in the Eastern Indonesia. The Triassic-Middle Jurassic marine carbonaceous shale sequences are the main hydrocarbon source rock in the Irian Jaya and surrounding area (Buton, gula and Seram basins). The main Mesozoic reservoir are the Kembelangan Formation in the Bintuni Basin of Irian Jaya and Bobong Formation in the North Sula Region. Exploration play types in the Eastern Indonesia can be divided into five types: 1 - Peri Cratonic, 2 - Marginal Rift Graben, 3 - Thrust Fold Belt Island Arc, 4 - Early Collision and 5 -Microcontinental Block - Advanced Collision. Recent discoveries through Mesozoic section in Eastern Indonesia are: Roabiba-1 (1990) in Bintuni Basin-Irian Jaya (Kambelangan Formation); Loku- 1 (1990) in North Sula region (Pre-Tertiary sediments); Oseil-1 (1993/94) in Bula-Seram Basin (Jurassic Manusela Formation); Elang-1 (1 994); Kakaktua-1 (1994) and Laminaria-1 in North Bonaparte Basin (Upper Jurassic Sands).

  20. Forestry management for sustainable development. EDI Policy Seminar Report 32

    SciTech Connect (OSTI)

    D`Silva, E.; Appanah, S.

    1993-09-01

    Forests will continue to disappear rapidly, the authors contend, until they are recognized as a valuable economic resource. This paper examines the causes of deforestation in Asia and suggests practical ways to achieve sustainable forest management. The report focuses on commercial logging, demand for firewood and fodder, and clearing forest land for farming. Economic policies and forest institutions have failed to protect natural forests. The authors point out technical problems that hinder forest management, such as improper tree harvesting. They describe conflicting goals among forest users and government investments that deplete forests. The authors argue that sustainable forest management calls for sound pricing policies and strong institutions to enforce them. They discuss benefit-sharing schemes that give local people incentives to protect forests and new ways to manage tree plantations to serve many different users. Detailed case studies look at effective forest management programs in Indonesia, Malaysia, Papua New Guinea, and the Philippines. The paper examines profitable opportunities for trade in environmental services. Such trade would involve industrial countries paying developing nations not to clear their natural forests. The protected forests would help reduce global carbon emissions and preserve biodiversity.

  1. Atmospheric Radiation Measurement (ARM) Data from the Tropical Western Pacific (TWP) Site.

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    ARM maintains four major, permanent sites for data collection and deploys the ARM Mobile Facility to other sites as determined. The Tropical Western Pacific (TWP) site is one of the four fixed sites. It consists of three climate research facilities; the Manus facility on Los Negros Island in Manus, Papua New Guinea (established in 1996); the Nauru facility on Nauru Island, Republic of Nauru (1998); and the Darwin facility in Darwin, Northern Territory, Australia (2002). The operations are supported by government agencies in each host country. Covering the area roughly between 10 degrees N and 10 degrees S of the equator and from 130 degrees E to 167 degrees E, the TWP locale includes a region that plays a large role in the interannual variability observed in the global climate system. More than 250,000 TWP data sets from 1996 to the present reside in the ARM Archive. Begin at the TWP information page for links or access data directly from the ARM Archive at http://www.archive.arm.gov/. Users will need to register for a password, but all files are then free for viewing or downloading. The ARM Archive physically resides at the Oak Ridge National Laboratory.

  2. Assessing health impacts in complex eco-epidemiological settings in the humid tropics: Modular baseline health surveys

    SciTech Connect (OSTI)

    Winkler, Mirko S.; Divall, Mark J.; Krieger, Gary R.; Schmidlin, Sandro; Magassouba, Mohamed L.; Knoblauch, Astrid M.; Singer, Burton H.; Utzinger, Juerg

    2012-02-15

    The quantitative assessment of health impacts has been identified as a crucial feature for realising the full potential of health impact assessment (HIA). In settings where demographic and health data are notoriously scarce, but there is a broad range of ascertainable ecological, environmental, epidemiological and socioeconomic information, a diverse toolkit of data collection strategies becomes relevant for the mainly small-area impacts of interest. We present a modular, cross-sectional baseline health survey study design, which has been developed for HIA of industrial development projects in the humid tropics. The modular nature of our toolkit allows our methodology to be readily adapted to the prevailing eco-epidemiological characteristics of a given project setting. Central to our design is a broad set of key performance indicators, covering a multiplicity of health outcomes and determinants at different levels and scales. We present experience and key findings from our modular baseline health survey methodology employed in 14 selected sentinel sites within an iron ore mining project in the Republic of Guinea. We argue that our methodology is a generic example of rapid evidence assembly in difficult-to-reach localities, where improvement of the predictive validity of the assessment and establishment of a benchmark for longitudinal monitoring of project impacts and mitigation efforts is needed.

  3. Mineral industries of Australia, Canada, and Oceania (including a discussion of Antarctica's mineral resources). Mineral perspective

    SciTech Connect (OSTI)

    Kimbell, C.L.; Lyday, T.Q.; Newman, H.H.

    1985-12-01

    The Bureau of Mines report gives the mineral industry highlights of two of the world's major mineral producing countries, Australia and Canada, and seven Pacific island nations or territories--Fiji, New Caledonia, New Zealand, Papua New Guinea, Republic of Nauru, Solomon Islands, and Vanuatu. The mineral resources of Antarctica are also discussed. Because of the size of the Australian and Canadian mineral industries, summary reviews are presented for each of the States, Provinces, or Territories. The most current information available from all nations is given on major minerals or mineral-commodity production, share of world production, and reserves. Reported also are significant mining companies, locations and capacities of their main facilities, and their share of domestic production. Other information is provided on mineral-related trade with the United States, government mineral policy, energy production-consumption and trade, the mining industry labor force, and prospects for the mineral industry. Maps show the locations of selected mineral deposits, oilfields and gasfields, mines, and processing facilities including iron and steel plants, nonferrous smelters and refineries, and cement plants, as well as infrastructure pertinent to the mineral industry.

  4. Quantification of the epitope diversity of HIV-1-specific binding antibodies by peptide microarrays for global HIV-1 vaccine development

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Stephenson, Kathryn E.; Neubauer, George H.; Reimer, Ulf; Pawlowski, Nikolaus; Knaute, Tobias; Zerweck, Johannes; Korber, Bette T.; Barouch, Dan H.

    2014-11-14

    An effective vaccine against human immunodeficiency virus type 1 (HIV-1) will have to provide protection against a vast array of different HIV-1 strains. Current methods to measure HIV-1-specific binding antibodies following immunization typically focus on determining the magnitude of antibody responses, but the epitope diversity of antibody responses has remained largely unexplored. Here we describe the development of a global HIV-1 peptide microarray that contains 6564 peptides from across the HIV-1 proteome and covers the majority of HIV-1 sequences in the Los Alamos National Laboratory global HIV-1 sequence database. Using this microarray, we quantified the magnitude, breadth, and depth ofmore » IgG binding to linear HIV-1 sequences in HIV-1-infected humans and HIV-1-vaccinated humans, rhesus monkeys and guinea pigs. The microarray measured potentially important differences in antibody epitope diversity, particularly regarding the depth of epitope variants recognized at each binding site. Our data suggest that the global HIV-1 peptide microarray may be a useful tool for both preclinical and clinical HIV-1 research.« less

  5. Dielectric-Lined High-Gradient Accelerator Structure

    SciTech Connect (OSTI)

    Jay L. Hirshfield

    2012-04-24

    Rectangular particle accelerator structures with internal planar dielectric elements have been studied, with a view towards devising structures with lower surface fields for a given accelerating field, as compared with structures without dielectrics. Success with this concept is expected to allow operation at higher accelerating gradients than otherwise on account of reduced breakdown probabilities. The project involves studies of RF breakdown on amorphous dielectrics in test cavities that could enable high-gradient structures to be built for a future multi-TeV collider. The aim is to determine what the limits are for RF fields at the surfaces of selected dielectrics, and the resulting acceleration gradient that could be achieved in a working structure. The dielectric of principal interest in this study is artificial CVD diamond, on account of its advertised high breakdown field ({approx}2 GV/m for dc), low loss tangent, and high thermal conductivity. Experimental studies at mm-wavelengths on materials and structures for achieving high acceleration gradient were based on the availability of the 34.3 GHz third-harmonic magnicon amplifier developed by Omega-P, and installed at the Yale University Beam Physics Laboratory. Peak power from the magnicon was measured to be about 20 MW in 0.5 {micro}s pulses, with a gain of 54 dB. Experiments for studying RF high-field effects on CVD diamond samples failed to show any evidence after more than 10{sup 5} RF pulses of RF breakdown up to a tangential surface field strength of 153 MV/m; studies at higher fields were not possible due to a degradation in magnicon performance. A rebuild of the tube is underway at this writing. Computed performance for a dielectric-loaded rectangular accelerator structure (DLA) shows highly competitive properties, as compared with an existing all-metal structure. For example, comparisons were made of a DLA structure having two planar CVD diamond elements with a all-metal CERN structure HDS operating at 30 GHz. It was shown that the ratio of maximum surface electric field to accelerating field at the metal wall is only 0.35-0.4 for DLA, much smaller than the value 2.2 for HDS; and the ratio of surface magnetic field to accelerating field is 3.0 mA/V for DLA, compared with 3.45 mA/V for HDS. These values bode well for DLA in helping to avoid breakdown and to reducing pulsed surface heating and fatigue. The shunt impedance is found to be 160-175 M{Omega}/m for DLA, as compared to 99 M{Omega}/m for HDS. Conclusions are reached from this project that CVD diamond appears promising as a dielectric with a high threshold for RF breakdown, and that rectangular accelerator structures can be devised using planar CVD diamond elements that could be operated at higher acceleration gradients with low probability of RF breakdown, as compared with corresponding all-metallic structures.

  6. Trees Containing Built-In Pulping Catalysts - Final Report - 08/18/1997 - 08/18/2000

    SciTech Connect (OSTI)

    Pullman, G.; Dimmel, D.; Peter, G.

    2000-08-18

    Several hardwood and softwood trees were analyzed for the presence of anthraquinone-type molecules. Low levels of anthraquinone (AQ) and anthrone components were detected using gas chromatography-mass spectroscopy and sensitive selected-ion monitoring techniques. Ten out of seventeen hardwood samples examined contained AQ-type components; however, the levels were typically below {approximately}6 ppm. No AQs were observed in the few softwood samples that were examined. The AQs were more concentrated in the heartwood of teak than in the sapwood. The delignification of pine was enhanced by the addition of teak chips ({approximately}0.7% AQ-equivalence content) to the cook, suggesting that endogenous AQs can be released from wood during pulping and can catalyze delignification reactions. Eastern cottonwood contained AQ, methyl AQ, and dimethyl AQ, all useful for wood pulping. This is the first time unsubstituted AQ has been observed in wood extracts. Due to the presence of these pulping catalysts, rapid growth rates in plantation settings, and the ease of genetic transformation, eastern cottonwood is a suitable candidate for genetic engineering studies to enhance AQ content. To achieve effective catalytic pulping activity, poplar and cottonwood, respectively, require {approximately}100 and 1000 times more for pulping catalysts. A strategy to increase AQ concentration in natural wood was developed and is currently being tested. This strategy involves ''turning up'' isochorismate synthase (ICS) through genetic engineering. Isochorismate synthase is the first enzyme in the AQ pathway branching from the shikimic acid pathway. In general, the level of enzyme activity at the first branch point or committed step controls the flux through a biosynthetic pathway. To test if the level of ICS regulates AQ biosynthesis in plant tissues, we proposed to over-express this synthase in plant cells. A partial cDNA encoding a putative ICS was available from the random cDNA sequencing project carried out with Arabidopsis thaliana. We used this putative plant ICS gene fragment to isolate and sequence a full-length ICS cDNA from Arabidopsis thaliana. The putative full-length cDNA encodes for a 569 amino acid protein of {approximately}62kDa. This sequence represents the first full-length ICS cDNA isolated from a plant. When inserted into E. coli, our isolated cDNA over-expressed ICS protein in the insoluble inclusion bodies. A plant expression vector containing the ICS cDNA, NP II for selection on the antibiotic kanamycin, and duplicated 35S-cauliflower mosaic virus promoter were inserted into Agrobacterium tumefaciens strain GV3101. Transformation experiments for insertion of these foreign genes into Populus deltoides 'C175' resulted in eight lines able to regenerate shoots and grow roots in the presence of kanamycin. Plants from these eight lines have acclimated to growth in sterile soil and will be moved to a greenhouse environment in spring 2001. Non rooted shoots from each line are currently being multiplied by shoot culture. When enough shoot tissue and/or greenhouse plant stem tissue is available, AQ analysis will be done and compared with non transformed control tissue.

  7. Spatial Variability of Surface Irradiance Measurements at the Manus ARM Site

    SciTech Connect (OSTI)

    Riihimaki, Laura D.; Long, Charles N.

    2014-05-16

    The location of the Atmospheric Radiation Measurement (ARM) site on Manus island in Papua New Guinea was chosen because it is very close the coast, in a geographically at, near-sea level area of the island, minimizing the impact of local island effects on the meteorology of the measurements [Ackerman et al., 1999]. In this study, we confirm that the Manus site is in deed less impacted by the island meteorology than slightly inland by comparing over a year of broadband surface irradiance and ceilometer measurements and derived quantities at the standard Manus site and a second location 7 km away as part of the AMIE-Manus campaign. The two sites show statistically similar distributions of irradiance and other derived quantities for all wind directions except easterly winds, when the inland site is down wind from the standard Manus site. Under easterly wind conditions, which occur 17% of the time, there is a higher occurrence of cloudiness at the down wind site likely do to land heating and orographic effects. This increased cloudiness is caused by shallow, broken clouds often with bases around 700 m in altitude. While the central Manus site consistently measures a frequency of occurrence of low clouds (cloud base height less than 1200 m) about 25+4% regardless of wind direction, the AMIE site has higher frequencies of low clouds (38%) when winds are from the east. This increase in low, locally produced clouds causes an additional -20 W/m2 shortwave surface cloud radiative effect at the AMIE site in easterly conditions than in other meteorological conditions that exhibit better agreement between the two sites.

  8. The East Asia geographic map series

    SciTech Connect (OSTI)

    Terman, M.J.; Bell, E.P. )

    1990-06-01

    During the last 15 years, the Circum-Pacific Map Project Northwest Quadrant Panel (NWQP) has created a map inventory of geoscience data at a scale of 1:10,000,000. Now, for East Asia, a second set of thematic maps is being initiated cooperatively by the Circum-Pacific Council for Energy and Mineral Resources and the Committee for Coordination of Joint Prospecting for Mineral Resources in Asian Offshore Areas (CCOP). These new maps will constitute the East Asia Map Project, and they will present geoscience parameters at a scale of 1:2,000,000 that can be used to evaluate the potential for undiscovered resources with the application of new deposit modeling methodologies. The following map series are being compiled or are under consideration: geography, geotectonics, geophysics, mineral resources, energy resources, and hazards. The U.S, Geological Survey (USGS) is compiling the East Asia Geographic Map Series. Shorelines, rivers, and international boundaries have been computer plotted by the National Mapping Division from the most detailed version of the World Data Bank II (WDB II). This publicly available bank was hand digitized from a 1:3,000,000-scale global map compiled from a variety of sources. The East Asia series is composed of eight overlapping sheets with Lambert Azimuthal Equal-Area Projection having a common point of origin at 120{degree}E and 15{degree}N; neatlines for each sheet are 39{degree} {times} 54.4{degree}. Titles reflect each map's coverage: Sheet 1, Japan/Korea/Northeast China; Sheet 2, Southeast China; Sheet 3, Southeast Asia; Sheet 4, Philippines; Sheet 5, Malaysia/ West Indonesia; Sheet 6, East Indonesia; Sheet 7, Papua New Guinea/ Solomon Islands; and Sheet 8, Western Pacific Islands. Contours have been scribed by the USGS's Office of International Geology.

  9. Differences between nonprecipitating tropical and trade wind marine shallow cumuli

    SciTech Connect (OSTI)

    Ghate, Virendra P.; Miller, Mark A.; Zhu, Ping

    2015-11-13

    In this study, marine nonprecipitating cumulus topped boundary layers (CTBLs) observed in a tropical and in a trade wind region are contrasted based on their cloud macrophysical, dynamical, and radiative structures. Data from the Atmospheric Radiation Measurement (ARM) observational site previously operating at Manus Island, Papua New Guinea, and data collected during the deployment of ARM Mobile Facility at the island of Graciosa, in the Azores, were used in this study. The tropical marine CTBLs were deeper, had higher surface fluxes and boundary layer radiative cooling, but lower wind speeds compared to their trade wind counterparts. The radiative velocity scale was 50%-70% of the surface convective velocity scale at both locations, highlighting the prominent role played by radiation in maintaining turbulence in marine CTBLs. Despite greater thicknesses, the chord lengths of tropical cumuli were on average lower than those of trade wind cumuli, and as a result of lower cloud cover, the hourly averaged (cloudy and clear) liquid water paths of tropical cumuli were lower than the trade wind cumuli. At both locations ~70% of the cloudy profiles were updrafts, while the average amount of updrafts near cloud base stronger than 1 m s–1 was ~22% in tropical cumuli and ~12% in the trade wind cumuli. The mean in-cloud radar reflectivity within updrafts and mean updraft velocity was higher in tropical cumuli than the trade wind cumuli. Despite stronger vertical velocities and a higher number of strong updrafts, due to lower cloud fraction, the updraft mass flux was lower in the tropical cumuli compared to the trade wind cumuli. The observations suggest that the tropical and trade wind marine cumulus clouds differ significantly in their macrophysical and dynamical structures

  10. Use of ARM observations and numerical models to determine radiative and latent heating profiles of mesoscale convective systems for general circulation models

    SciTech Connect (OSTI)

    Tao, Wei-Kuo; Houze, Robert, A., Jr.; Zeng, Xiping

    2013-03-14

    This three-year project, in cooperation with Professor Bob Houze at University of Washington, has been successfully finished as planned. Both ARM (the Atmospheric Radiation Measurement Program) data and cloud-resolving model (CRM) simulations were used to identify the water budgets of clouds observed in two international field campaigns. The research results achieved shed light on several key processes of clouds in climate change (or general circulation models), which are summarized below. 1. Revealed the effect of mineral dust on mesoscale convective systems (MCSs) Two international field campaigns near a desert and a tropical coast provided unique data to drive and evaluate CRM simulations, which are TWP-ICE (the Tropical Warm Pool International Cloud Experiment) and AMMA (the African Monsoon Multidisciplinary Analysis). Studies of the two campaign data were contrasted, revealing that much mineral dust can bring about large MCSs via ice nucleation and clouds. This result was reported as a PI presentation in the 3rd ASR Science Team meeting held in Arlington, Virginia in March 2012. A paper on the studies was published in the Journal of the Atmospheric Sciences (Zeng et al. 2013). 2. Identified the effect of convective downdrafts on ice crystal concentration Using the large-scale forcing data from TWP-ICE, ARM-SGP (the Southern Great Plains) and other field campaigns, Goddard CRM simulations were carried out in comparison with radar and satellite observations. The comparison between model and observations revealed that convective downdrafts could increase ice crystal concentration by up to three or four orders, which is a key to quantitatively represent the indirect effects of ice nuclei, a kind of aerosol, on clouds and radiation in the Tropics. This result was published in the Journal of the Atmospheric Sciences (Zeng et al. 2011) and summarized in the DOE/ASR Research Highlights Summaries (see http://www.arm.gov/science/highlights/RMjY5/view). 3. Used radar observations to evaluate model simulations In cooperation with Profs. Bob Houze at University of Washington and Steven Rutledge at Colorado State University, numerical model results were evaluated with observations from W- and C-band radars and CloudSat/TRMM satellites. These studies exhibited some shortcomings of current numerical models, such as too little of thin anvil clouds, directing the future improvement of cloud microphysics parameterization in CRMs. Two papers of Powell et al (2012) and Zeng et al. (2013), summarizing these studies, were published in the Journal of the Atmospheric Sciences. 4. Analyzed the water budgets of MCSs Using ARM data from TWP-ICE, ARM-SGP and other field campaigns, the Goddard CRM simulations were carried out to analyze the water budgets of clouds from TWP-ICE and AMMA. The simulations generated a set of datasets on clouds and radiation, which are available http://cloud.gsfc.nasa.gov/. The cloud datasets were available for modelers and other researchers aiming to improve the representation of cloud processes in multi-scale modeling frameworks, GCMs and climate models. Special datasets, such as 3D cloud distributions every six minutes for TWP-ICE, were requested and generated for ARM/ASR investigators. Data server records show that 86,206 datasets were downloaded by 120 users between April of 2010 and January of 2012. 5. MMF simulations The Goddard MMF (multi-scale modeling framework) has been improved by coupling with the Goddard Land Information System (LIS) and the Goddard Earth Observing System Model, Version 5 (GOES5). It has also been optimized on NASA HEC supercomputers and can be run over 4000 CPUs. The improved MMF with high horizontal resolution (1 x 1 degree) is currently being applied to cases covering 2005 and 2006. The results show that the spatial distribution pattern of precipitation rate is well simulated by the MMF through comparisons with satellite retrievals from the CMOPRH and GPCP data sets. In addition, the MMF results were compared with three reanalyses (MERRA, ERA-Interim and CFSR). Although the MMF tends to produce a higher precipitation rate over some topical regions, it actually well captures the variations in the zonal and meridional means. Among the three reanalyses, ERA-Interim seems to have values close to those of the satellite retrievals especially for GPCP. It is interesting to note that the MMF obtained the best results in the rain forest of Africa even better than those of CFSR and ERA-Interim, when compared to CMORPH. MERRA fails to capture the precipitation in this region. We are now collaborating with Steve Rutledge (CSU) to validate the model results for AMMA 6. MC3E and the diurnal variation of precipitation processes The Midlatitude Continental Convective Clouds Experiment (MC3E) was a joint field campaign between the U.S. Department of Energy (DOE) Atmospheric Radiation Measurement (ARM) Climate Research Facility and the NASA Global Precipitation Measurement (GPM) mission Ground Validation (GV) program. It took place in central Oklahoma during the period April 22 _ June 6, 2011. Some of its major objectives involve the use of CRMs in precipitation science such as: (1) testing the fidelity of CRM simulations via intensive statistical comparisons between simulated and observed cloud properties and latent heating fields for a variety of case types, (2) establishing the limits of CRM space-time integration capabilities for quantitative precipitation estimates, and (3) supporting the development and refinement of physically-based GMI, DPR, and DPR-GMI combined retrieval algorithms using ground-based GPM GV Ku-Ka band radar and CRM simulations. The NASA unified WRF model (nu-WRF) was used for real time forecasts during the field campaign, and ten precipitation events were selected for post mission simulations. These events include well-organized squall lines, scattered storms and quasi-linear storms. A paper focused on the diurnal variation of precipitation will be submitted in September 2012. The major highlights are as follows: a. The results indicate that NU-WRF model could capture observed diurnal variation of rainfall (composite not individual); b. NU-WRF model could simulate two different types (propagating and local type) of the diurnal variation of rainfall; c. NU-WRF model simulation show very good agreement with observation in terms of precipitation pattern (linear MCS), radar reflectivity (a second low peak – shallow convection); d. NU-WRF model simulation indicates that the cool-pool dynamic is the main physical process for MCS propagation speed; e. Surface heat fluxes (including land surface model and initial surface condition) do not play a major role in phase of diurnal variation (change rainfall amount slightly); f. Terrain effect is important for initial stage of MCS (rainfall is increased and close to observation by increasing the terrain height that is also close to observed); g. Diurnal variation of radiation is not important for the simulated variation of rainfall. Publications: Zeng, X., W.-K. Tao, S. Powell, R. Houze, Jr., P. Ciesielski, N. Guy, H. Pierce and T. Matsui, 2012: A comparison of the water budgets between clouds from AMMA and TWP-ICE. J. Atmos. Sci., 70, 487-503. Powell, S. W., R. A. Houze, Jr., A. Kumar, and S. A. McFarlane, 2012: Comparison of simulated and observed continental tropical anvil clouds and their radiative heating profiles. J. Atmos. Sci., 69, 2662-2681. Zeng, X., W.-K. Tao, T. Matsui, S. Xie, S. Lang, M. Zhang, D. Starr, and X. Li, 2011: Estimating the Ice Crystal Enhancement Factor in the Tropics. J. Atmos. Sci., 68, 1424-1434. Conferences: Zeng, X., W.-K. Tao, S. Powell, R. Houze, Jr., P. Ciesielski, N. Guy, H. Pierce and T. Matsui, 2012: Comparison of water budget between AMMA and TWP-ICE clouds. The 3rd Annual ASR Science Team Meeting. Arlington, Virginia, Mar. 12-16, 2012. Zeng, X., W.-K. Tao, S. Powell, R. A. Houze Jr., and P. Ciesielski, 2011: Comparing the water budgets between AMMA and TWP-ICE clouds. Fall 2011 ASR Working Group Meeting. Annapolis, September 12-16, 2011. Zeng, X. et al., 2011: Introducing ice nuclei into turbulence parameterizations in CRMs. Fall 2011 ASR Working Group Meeting. Annapolis, September 12-16, 2011.

  11. Anti-addiction drug ibogaine inhibits voltage-gated ionic currents: A study to assess the drug's cardiac ion channel profile

    SciTech Connect (OSTI)

    Koenig, Xaver; Kovar, Michael; Rubi, Lena; Mike, Agnes K.; Lukacs, Peter; Gawali, Vaibhavkumar S.; Todt, Hannes; Hilber, Karlheinz; Sandtner, Walter

    2013-12-01

    The plant alkaloid ibogaine has promising anti-addictive properties. Albeit not licenced as a therapeutic drug, and despite hints that ibogaine may perturb the heart rhythm, this alkaloid is used to treat drug addicts. We have recently reported that ibogaine inhibits human ERG (hERG) potassium channels at concentrations similar to the drugs affinity for several of its known brain targets. Thereby the drug may disturb the heart's electrophysiology. Here, to assess the drug's cardiac ion channel profile in more detail, we studied the effects of ibogaine and its congener 18-Methoxycoronaridine (18-MC) on various cardiac voltage-gated ion channels. We confirmed that heterologously expressed hERG currents are reduced by ibogaine in low micromolar concentrations. Moreover, at higher concentrations, the drug also reduced human Na{sub v}1.5 sodium and Ca{sub v}1.2 calcium currents. Ion currents were as well reduced by 18-MC, yet with diminished potency. Unexpectedly, although blocking hERG channels, ibogaine did not prolong the action potential (AP) in guinea pig cardiomyocytes at low micromolar concentrations. Higher concentrations (? 10 ?M) even shortened the AP. These findings can be explained by the drug's calcium channel inhibition, which counteracts the AP-prolonging effect generated by hERG blockade. Implementation of ibogaine's inhibitory effects on human ion channels in a computer model of a ventricular cardiomyocyte, on the other hand, suggested that ibogaine does prolong the AP in the human heart. We conclude that therapeutic concentrations of ibogaine have the propensity to prolong the QT interval of the electrocardiogram in humans. In some cases this may lead to cardiac arrhythmias. - Highlights: We study effects of anti-addiction drug ibogaine on ionic currents in cardiomyocytes. We assess the cardiac ion channel profile of ibogaine. Ibogaine inhibits hERG potassium, sodium and calcium channels. Ibogaines effects on ion channels are a potential source of cardiac arrhythmias. 18-Methoxycoronaridine has a lower affinity for cardiac ion channels than ibogaine.

  12. Radiative Heating of the ISCCP Upper Level Cloud Regimes and its Impact on the Large-scale Tropical Circulation

    SciTech Connect (OSTI)

    Li, Wei; Schumacher, Courtney; McFarlane, Sally A.

    2013-01-31

    Radiative heating profiles of the International Satellite Cloud Climatology Project (ISCCP) cloud regimes (or weather states) were estimated by matching ISCCP observations with radiative properties derived from cloud radar and lidar measurements from the Department of Energy (DOE) Atmospheric Radiation Measurement (ARM) sites at Manus, Papua New Guinea, and Darwin, Australia. Focus was placed on the ISCCP cloud regimes containing the majority of upper level clouds in the tropics, i.e., mesoscale convective systems (MCSs), deep cumulonimbus with cirrus, mixed shallow and deep convection, and thin cirrus. At upper levels, these regimes have average maximum cloud occurrences ranging from 30% to 55% near 12 km with variations depending on the location and cloud regime. The resulting radiative heating profiles have maxima of approximately 1 K/day near 12 km, with equal heating contributions from the longwave and shortwave components. Upper level minima occur near 15 km, with the MCS regime showing the strongest cooling of 0.2 K/day and the thin cirrus showing no cooling. The gradient of upper level heating ranges from 0.2 to 0.4 K/(day∙km), with the most convectively active regimes (i.e., MCSs and deep cumulonimbus with cirrus) having the largest gradient. When the above heating profiles were applied to the 25-year ISCCP data set, the tropics-wide average profile has a radiative heating maximum of 0.45Kday-1 near 250 hPa. Column-integrated radiative heating of upper level cloud accounts for about 20% of the latent heating estimated by the Tropical Rainfall Measuring Mission (TRMM) Precipitation Radar (PR). The ISCCP radiative heating of tropical upper level cloud only slightly modifies the response of an idealized primitive equation model forced with the tropics-wide TRMM PR latent heating, which suggests that the impact of upper level cloud is more important to large-scale tropical circulation variations because of convective feedbacks rather than direct forcing by the cloud radiative heating profiles. However, the height of the radiative heating maxima and gradient of the heating profiles are important to determine the sign and patterns of the horizontal circulation anomaly driven by radiative heating at upper levels.

  13. Sex-related differences in murine hepatic transcriptional and proteomic responses to TCDD

    SciTech Connect (OSTI)

    Prokopec, Stephenie D.; Watson, John D.; Lee, Jamie; Pohjanvirta, Raimo; Boutros, Paul C.

    2015-04-15

    2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is an environmental contaminant that produces myriad toxicities in most mammals. In rodents alone, there is a huge divergence in the toxicological response across species, as well as among different strains within a species. But there are also significant differences between males and females animals of a single strain. These differences are inconsistent across model systems: the severity of toxicity is greater in female rats than males, while male mice and guinea pigs are more sensitive than females. Because the specific events that underlie this difference remain unclear, we characterized the hepatic transcriptional response of adult male and female C57BL/6 mice to 500 μg/kg TCDD at multiple time-points. The transcriptional profile diverged significantly between the sexes. Female mice demonstrated a large number of altered transcripts as early as 6 h following treatment, suggesting a large primary response. Conversely, male animals showed the greatest TCDD-mediated response 144 h following exposure, potentially implicating significant secondary responses. Nr1i3 was statistically significantly induced at all time-points in the sensitive male animals. This mRNA encodes the constitutive androstane receptor (CAR), a transcription factor involved in the regulation of xenobiotic metabolism, lipid metabolism, cell cycle and apoptosis. Surprisingly though, changes at the protein level (aside from the positive control, CYP1A1) were modest, with only FMO3 showing clear induction, and no genes with sex-differences. Thus, while male and female mice show transcriptional differences in their response to TCDD, their association with TCDD-induced toxicities remains unclear. - Highlights: • Differences exist between the toxicity phenotypes to TCDD in male and female mice. • TCDD-mediated transcriptomic differences were identified between the sexes. • Resistant female mice displayed a large, early-onset, transcriptomic response. • Sensitive male mice displayed a large, late-onset, transcriptomic response. • Fmo2, Fmo3 and Nr1i3 were induced across the time-course in only male mice.

  14. Parameterization and analysis of 3-D radiative transfer in clouds

    SciTech Connect (OSTI)

    Varnai, Tamas

    2012-03-16

    This report provides a summary of major accomplishments from the project. The project examines the impact of radiative interactions between neighboring atmospheric columns, for example clouds scattering extra sunlight toward nearby clear areas. While most current cloud models donâ??t consider these interactions and instead treat sunlight in each atmospheric column separately, the resulting uncertainties have remained unknown. This project has provided the first estimates on the way average solar heating is affected by interactions between nearby columns. These estimates have been obtained by combining several years of cloud observations at three DOE Atmospheric Radiation Measurement (ARM) Climate Research Facility sites (in Alaska, Oklahoma, and Papua New Guinea) with simulations of solar radiation around the observed clouds. The importance of radiative interactions between atmospheric columns was evaluated by contrasting simulations that included the interactions with those that did not. This study provides lower-bound estimates for radiative interactions: It cannot consider interactions in cross-wind direction, because it uses two-dimensional vertical cross-sections through clouds that were observed by instruments looking straight up as clouds drifted aloft. Data from new DOE scanning radars will allow future radiative studies to consider the full three-dimensional nature of radiative processes. The results reveal that two-dimensional radiative interactions increase overall day-and-night average solar heating by about 0.3, 1.2, and 4.1 Watts per meter square at the three sites, respectively. This increase grows further if one considers that most large-domain cloud simulations have resolutions that cannot specify small-scale cloud variability. For example, the increases in solar heating mentioned above roughly double for a fairly typical model resolution of 1 km. The study also examined the factors that shape radiative interactions between atmospheric columns and found that local effects were often much larger than the overall values mentioned above, and were especially large for high sun and near convective clouds such as cumulus. The study also found that statistical methods such as neural networks appear promising for enabling cloud models to consider radiative interactions between nearby atmospheric columns. Finally, through collaboration with German scientists, the project found that new methods (especially one called â??stepwise krigingâ?) show great promise in filling gaps between cloud radar scans. If applied to data from the new DOE scanning cloud radars, these methods can yield large, continuous three-dimensional cloud structures for future radiative simulations.