National Library of Energy BETA

Sample records for late submis sions

  1. FRm : John A. Deny, DitiSion Of

    Office of Legacy Management (LM)

    to : lieads of Divisions am3 Man DAW.: December 6, 1954 FRm : John A. Deny, DitiSion Of SPNBOL : csm-R:AcB The attached tabulation of active AEC contracts over $l,ooO,Mx) haa been ,xepared as a result of recurring requests fcr infmmatirm cm ow larger contracts. It consists ox- Pa-t I - E+ime contracts and Pert II - Sub- ccdxacts, and lists the contracts alphabetically bq Operations Office to shar; (1) tne of work being prformed by the contractcr; (2) contract rmter; (3).ac&ated dollar

  2. U. S. Attic Grsrgy 'bmiss~o3 U. S. Atomic lb-al-w CamLf3sion December 27, S.957

    Office of Legacy Management (LM)

    a . - 3 U. S. Attic Grsrgy 'bmiss~o3 U. S. Atomic lb-al-w CamLf3sion December 27, S.957

  3. THE WIRED SURVEY. IV. NEW DUST DISKS FROM THE McCOOK and SION WHITE DWARF CATALOG

    SciTech Connect (OSTI)

    Hoard, D. W.; Wachter, Stefanie; Debes, John H.; Leisawitz, David T.; Cohen, Martin

    2013-06-10

    We have compiled photometric data from the Wide-field Infrared Survey Explorer All Sky Survey and other archival sources for the more than 2200 objects in the original McCook and Sion Catalog of Spectroscopically Identified White Dwarfs. We applied color-selection criteria to identify 28 targets whose infrared spectral energy distributions depart from the expectation for the white dwarf (WD) photosphere alone. Seven of these are previously known WDs with circumstellar dust disks, five are known central stars of planetary nebulae, and six were excluded for being known binaries or having possible contamination of their infrared photometry. We fit WD models to the spectral energy distributions of the remaining ten targets, and find seven new candidates with infrared excess suggesting the presence of a circumstellar dust disk. We compare the model dust disk properties for these new candidates with a comprehensive compilation of previously published parameters for known WDs with dust disks. It is possible that the current census of WDs with dust disks that produce an excess detectable at K-band and shorter wavelengths is close to complete for the entire sample of known WDs to the detection limits of existing near-IR all-sky surveys. The WD dust disk candidates now being found using longer wavelength infrared data are drawn from a previously underrepresented region of parameter space, in which the dust disks are overall cooler, narrower in radial extent, and/or contain fewer emitting grains.

  4. Fourth Fridays - Museum Open Late

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Fourth Fridays - Museum Open Late Fourth Fridays - Museum Open Late WHEN: Oct 23, 2015 10:00 AM - 6:00 PM WHERE: Bradbury Science Museum 1350 Central Ave, Los Alamos, NM 87544 USA CONTACT: Jessica Privette 505 667-0375 CATEGORY: Bradbury INTERNAL: Calendar Login Fourth Fridays in Downtown Los Alamos Event Description The museum will be open late until 6 p.m. every Fourth Friday offering extended access to exhibits, special programming, and activities. The Los Alamos Creative District is

  5. Fourth Fridays - Museum Open Late

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Fourth Fridays - Museum Open Late Fourth Fridays - Museum Open Late WHEN: Jan 22, 2016 10:00 AM - 6:00 PM WHERE: Bradbury Science Museum 1350 Central Ave, Los Alamos, NM 87544 USA CONTACT: Linda Anderman (505) 665-9196 CATEGORY: Bradbury INTERNAL: Calendar Login Fourth Fridays in Downtown Los Alamos Event Description The museum will be open late until 6 p.m. every Fourth Friday offering extended access to exhibits, special programming, and activities. The Los Alamos Creative District is

  6. Fourth Fridays - Museum Open Late

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Science Museum is participating by staying open late until 6:00 p.m. offering access to exhibits and special activities for all ages. Admission is free and open to the public...

  7. Categorical ExcluSIon Determination Forn1

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    exercises and simulation I8lB 1.3 * Routine maintenance and custodial services DB 1,4 * Air conditioning installation for existing equipment DB 1.5 Cooling water system...

  8. Petrography of late cenozoic sediments, Raft River geothermal...

    Open Energy Info (EERE)

    of late cenozoic sediments, Raft River geothermal field, Idaho Jump to: navigation, search OpenEI Reference LibraryAdd to library Conference Proceedings: Petrography of late...

  9. Late glacial aridity in southern Rocky Mountains

    SciTech Connect (OSTI)

    Davis, O.K.; Pitblado, B.L.

    1995-09-01

    While the slopes of the present-day Colorado Rocky Mountains are characterized by large stands of subalpine and montane conifers, the Rockies of the late glacial looked dramatically different. Specifically, pollen records suggest that during the late glacial, Artemisia and Gramineae predominated throughout the mountains of Colorado. At some point between 11,000 and 10,000 B.P., however, both Artemisia and grasses underwent a dramatic decline, which can be identified in virtually every pollen diagram produced for Colorado mountain sites, including Como Lake (Sangre de Cristo Mountains), Copley Lake and Splains; Gulch (near Crested Butte), Molas Lake (San Juan Mountains), and Redrock Lake (Boulder County). Moreover, the same pattern seems to hold for pollen spectra derived for areas adjacent to Colorado, including at sites in the Chuska Mountains of New Mexico and in eastern Wyoming. The implications of this consistent finding are compelling. The closest modem analogues to the Artemisia- and Gramineae-dominated late-glacial Colorado Rockies are found in the relatively arid northern Great Basin, which suggests that annual precipitation was much lower in the late-glacial southern Rocky Mountains than it was throughout the Holocene.

  10. Technical bases DWPF Late Washing Facility

    SciTech Connect (OSTI)

    Fish, D.L.; Landon, L.F.

    1992-08-10

    A task force recommended that the technical feasibility of a Late Wash' facility be assessed [1]. In this facility, each batch of tetraphenylborate slurry from Tank 49 would be given a final wash to reduce the concentrations of nitrite and radiolysis products to acceptable levels. Laboratory-scale studies have demonstrated that d the nitrite content of the slurry fed to DWPF is reduced to 0.01 M or less (and at least a 4X reduction in concentration of the soluble species is attained), (1) the need for HAN during hydrolysis is eliminated (eliminating the production of ammonium ion during hydrolysis), (2) hydrolysis may be done with a catalyst concentration that will not exceed the copper solubility in glass and (3) the non-polar organic production during hydrolysis is significantly reduced. The first phase of an aggressive research and development program has been completed and all test results obtained to date support the technical feasibility of Late Washing. Paralleling this research and development effort is an aggressive design study directed by DWPF to scope and cost retrofitting the Auxiliary Pump Pit (APP) to enable performing a final wash of each batch of precipitate slurry before R is transferred into the DWPF Soft Processing Cell (SPC). An initial technical bases for the Late Wash Facility was transmitted to DWPF on June 15, 1992. Research and development activities are continuing directed principally at optimization of the cross-f low fitter decontamination methodology and pilot-scale validation of the recommended benzene stripping metodology.

  11. Late-time cosmological phase transitions

    SciTech Connect (OSTI)

    Schramm, D.N. Fermi National Accelerator Lab., Batavia, IL )

    1990-11-01

    It is shown that the potential galaxy formation and large-scale structure problems of objects existing at high redshifts (Z {approx gt} 5), structures existing on scales of 100M pc as well as velocity flows on such scales, and minimal microwave anisotropies ({Delta}T/T) {approx lt} 10{sup {minus}5} can be solved if the seeds needed to generate structure form in a vacuum phase transition after decoupling. It is argued that the basic physics of such a phase transition is no more exotic than that utilized in the more traditional GUT scale phase transitions, and that, just as in the GUT case, significant random gaussian fluctuations and/or topological defects can form. Scale lengths of {approximately}100M pc for large-scale structure as well as {approximately}1 M pc for galaxy formation occur naturally. Possible support for new physics that might be associated with such a late-time transition comes from the preliminary results of the SAGE solar neutrino experiment, implying neutrino flavor mixing with values similar to those required for a late-time transition. It is also noted that a see-saw model for the neutrino masses might also imply a tau neutrino mass that is an ideal hot dark matter candidate. However, in general either hot or cold dark matter can be consistent with a late-time transition. 47 refs., 2 figs.

  12. VERY LATE PHOTOMETRY OF SN 2011fe

    SciTech Connect (OSTI)

    Kerzendorf, W. E. [Department of Astronomy and Astrophysics, University of Toronto, 50 Saint George Street, Toronto, ON M5S 3H4 (Canada); Taubenberger, S.; Seitenzahl, I. R.; Ruiter, A. J., E-mail: wkerzendorf@gmail.com [Max-Planck-Institut fr Astrophysik, Karl-Schwarzschild-Strae 1, D-85748 Garching (Germany)

    2014-12-01

    The Type Ia supernova SN 2011fe is one of the closest supernovae of the past decades. Due to its proximity and low dust extinction, this object provides a very rare opportunity to study the extremely late time evolution (>900 days) of thermonuclear supernovae. In this Letter, we present our photometric data of SN 2011fe taken at an unprecedented late epoch of ?930 days with GMOS-N mounted on the Gemini North telescope (g=23.43 0.28, r=24.14 0.14, i=23.91 0.18, and z=23.90 0.17) to study the energy production and retention in the ejecta of SN 2011fe. Together with previous measurements by other groups, our result suggests that the optical supernova light curve can still be explained by the full thermalization of the decay positrons of {sup 56}Co. This is in spite of theoretical predicted effects (e.g., infrared catastrophe, positron escape, and dust) that advocate a substantial energy redistribution and/or loss via various processes that result in a more rapid dimming at these very late epochs.

  13. CategorIcal ExcluSIon Determination 1,'orn1

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and Guidelines OA 14 - Approval of technical exchange arrangements OA 15 - International umbrella agreements for energy R&D Facility Operations DB 1.2 - Training exercises and...

  14. Categ orical ExcluSIon DetermInation Fornl

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and Guidelines OA 14 - Approval of technical exchange arrangements DAIS - International umbrella agreements for energy R&D Facility Operations DB 1.2 - Training exercises and...

  15. CategorIcal ExcluSIon DetermInation Fornl

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and Guidelines OA I 4 - Approval of technical exchange arrangements DAIS - International umbrella agreements for energy R&D Facility Operations DB 1.2 - Training exercises and...

  16. Sion Power Corp formerly Moltech Corp | Open Energy Information

    Open Energy Info (EERE)

    Sector: Vehicles Product: Tucson, Arizona-based privately held developer of thin-film lithium-sulfur rechargeable batteries for propelling vehicles and other high energy-density...

  17. Early Proctoscopy is a Surrogate Endpoint of Late Rectal Toxicity...

    Office of Scientific and Technical Information (OSTI)

    Prostate Cancer Treated With Radiotherapy Citation Details In-Document Search Title: Early Proctoscopy is a Surrogate Endpoint of Late Rectal Toxicity in Prostate Cancer Treated ...

  18. Probing Late Neutrino Mass Properties With SupernovaNeutrinos...

    Office of Scientific and Technical Information (OSTI)

    Journal Article: Probing Late Neutrino Mass Properties With SupernovaNeutrinos Citation ... DOE Contract Number: DE-AC02-05CH11231 Resource Type: Journal Article Resource Relation: ...

  19. Have You Looked at Your Pipes Lately? | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Looked at Your Pipes Lately? Have You Looked at Your Pipes Lately? March 14, 2011 - 1:27pm Addthis Elizabeth Spencer Communicator, National Renewable Energy Laboratory You know, it doesn't matter that some of you are probably already thinking about spring. It doesn't matter that the bulk of winter is over for a lot of you. I'm going to say this anyway, because sometime, someday, it might be useful. Or, well, it might not be if you live in Florida. But for the rest of you, I will repeat this

  20. Radioactive demonstration of the late wash'' Precipitate Hydrolysis Process

    SciTech Connect (OSTI)

    Bibler, N.E.; Ferrara, D.M.; Ha, B.C.

    1992-06-30

    This report presents results of the radioactive demonstration of the DWPF Precipitate Hydrolysis Process as it would occur in the late wash'' flowsheet in the absence of hydroxylamine nitrate. Radioactive precipitate containing Cs-137 from the April, 1983, in-tank precipitation demonstration in Tank 48 was used for these tests.

  1. Radioactive demonstration of the ``late wash`` Precipitate Hydrolysis Process

    SciTech Connect (OSTI)

    Bibler, N.E.; Ferrara, D.M.; Ha, B.C.

    1992-06-30

    This report presents results of the radioactive demonstration of the DWPF Precipitate Hydrolysis Process as it would occur in the ``late wash`` flowsheet in the absence of hydroxylamine nitrate. Radioactive precipitate containing Cs-137 from the April, 1983, in-tank precipitation demonstration in Tank 48 was used for these tests.

  2. Technical bases DWPF Late Washing Facility. Revision 1

    SciTech Connect (OSTI)

    Fish, D.L.; Landon, L.F.

    1992-08-10

    A task force recommended that the technical feasibility of a ``Late Wash` facility be assessed [1]. In this facility, each batch of tetraphenylborate slurry from Tank 49 would be given a final wash to reduce the concentrations of nitrite and radiolysis products to acceptable levels. Laboratory-scale studies have demonstrated that d the nitrite content of the slurry fed to DWPF is reduced to 0.01 M or less (and at least a 4X reduction in concentration of the soluble species is attained), (1) the need for HAN during hydrolysis is eliminated (eliminating the production of ammonium ion during hydrolysis), (2) hydrolysis may be done with a catalyst concentration that will not exceed the copper solubility in glass and (3) the non-polar organic production during hydrolysis is significantly reduced. The first phase of an aggressive research and development program has been completed and all test results obtained to date support the technical feasibility of Late Washing. Paralleling this research and development effort is an aggressive design study directed by DWPF to scope and cost retrofitting the Auxiliary Pump Pit (APP) to enable performing a final wash of each batch of precipitate slurry before R is transferred into the DWPF Soft Processing Cell (SPC). An initial technical bases for the Late Wash Facility was transmitted to DWPF on June 15, 1992. Research and development activities are continuing directed principally at optimization of the cross-f low fitter decontamination methodology and pilot-scale validation of the recommended benzene stripping metodology.

  3. Major Design Changes Late in Title II or early in Title III Can...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Design Changes Late in Title II or early in Title III Can Be Costly PMLL Identifier: ... design changes occur late in Title II or early in Title III Discussion: Numerous ...

  4. Initial technical basis for late washing filter cleaning

    SciTech Connect (OSTI)

    Morrissey, M.F.; Dworjanyn, L.O.

    1992-07-23

    Bench scale filter cleaning tests at the Savannah River Technology Center have shown that cross-flow filter elements can be cleaned between late wash filtration runs and restored to original clean water flux conditions. The most effective cleaning technique was high flow axial recirculation, followed by flushing with caustic solution. Simple flushing with oxalic acid and caustic is less effective and is not recommended because of adverse experience in ITP filter cleaning and uncertainty in the.nature of radiolysis by-product contaminants.

  5. Hydrology of modern and late Holocene lakes, Death Valley, California

    SciTech Connect (OSTI)

    Grasso, D.N.

    1996-07-01

    Above-normal precipitation and surface-water runoff, which have been generally related to the cyclic recurrence of the El Nino-Southern Oscillation, have produced modern ephemeral lakes in the closed-basin Death Valley watershed. This study evaluates the regional hydroclimatic relations between precipitation, runoff, and lake transgressions in the Death Valley watershed. Recorded precipitation, runoff, and spring discharge data for the region are used in conjunction with a closed-basin, lake-water-budget equation to assess the relative contributions of water from these sources to modern lakes in Death Valley and to identify the requisite hydroclimatic changes for a late Holocene perennial lake in the valley. As part of the Yucca Mountain Site Characterization Program, an evaluation of the Quaternary regional paleoflood hydrology of the potential nuclear-waste repository site at Yucca Mountain, Nevada, was planned. The objectives of the evaluation were (1) to identify the locations and investigate the hydraulic characteristics of paleofloods and compare these with the locations and characteristics of modern floods, and (2) to evaluate the character and severity of past floods and debris flows to ascertain the potential future hazards to the potential repository during the pre-closure period (US Department of Energy, 1988). This study addresses the first of these objectives, and the second in part, by assessing and comparing the sizes, locations, and recurrence rates of modern, recorded (1962--83) floods and late Holocene paleofloods for the 8,533-mi{sup 2}, closed-basin, Death Valley watershed with its contributing drainage basins in the Yucca Mountain site area.

  6. Hydrolysis of late-washed, irradiated tetraphenylborate slurry simulants I: Phenylboric acid hydrolysis kinetics

    SciTech Connect (OSTI)

    Marek, J.C.

    2000-02-10

    The attached report details the kinetics of phenylboric acid reaction at 90 degrees C during precipitate hydrolysis processing of late-washed, irradiated tetraphenylborate slurry simulants.

  7. Late Cenozoic fault kinematics and basin development, Calabrian arc, Italy

    SciTech Connect (OSTI)

    Knott, S.D.; Turco, E.

    1988-08-01

    Current views for explaining the present structure of the Calabrian arc emphasize bending or buckling of an initially straight zone by rigid indentation. Although bending has played an important role, bending itself cannot explain all structural features now seen in the arc for the following reasons: (1) across-arc extension is inconsistent with buckling, (2) north-south compression predicted by a bending mechanism to occur in the internal part of a curved mountain belt is not present in the Calabrian arc, and (3) lateral shear occurs throughout the arc, not just along the northern and southern boundaries. The model presented here is based on lateral bending of mantle and lower crust (demonstrated by variation in extension in the Tyrrhenian basin) and semibrittle faulting and block rotation in the upper crust. These two styles of deformation are confined to the upper plate of the Calabrian subduction system. This deformation is considered to have been active from the beginning of extension in the Tyrrhenian basin (late Tortonian) and is still active today (based on Holocene seismicity). Block rotations are a consequence of lateral heterogeneous shear during extension. Therefore, some of the observed rotation of paleo-magnetic declinations may have occurred in areas undergoing extension and not just during thrusting. Inversion of sedimentary basins by block rotation is predicted by the model. The model will be a useful aid in interpreting reflection seismic data and exploring and developing offshore and onshore sedimentary basins in southern Italy.

  8. EARLY- AND LATE-TIME OBSERVATIONS OF SN 2008ha: ADDITIONAL CONSTRAINTS...

    Office of Scientific and Technical Information (OSTI)

    We also present late-time imaging and spectroscopy that are consistent with this scenario. Authors: Foley, Ryan J. ; Challis, Peter J. ; Kirshner, Robert P. 1 ; Brown, Peter J. ...

  9. Theoretical physicist Evgeny Epelbaum joined Jefferson Lab late in 2003 as

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    the inaugural Nathan Isgur Distinguished Postdoctoral Fellow | Jefferson Lab Theoretical physicist Evgeny Epelbaum joined Jefferson Lab late in 2003 as the inaugural Nathan Isgur Distinguished Postdoctoral Fellow Theoretical physicist Evgeny Epelbaum joined Jefferson Lab late in 2003 as the inaugural Nathan Isgur Distinguished Postdoctoral Fellow. May 12, 2004 The Department of Energy's Jefferson Lab and the Southeastern Universities Research Association (SURA) established the Nathan Isgur

  10. Models and correlations of the DEBRIS Late-Phase Melt Progression Model

    SciTech Connect (OSTI)

    Schmidt, R.C.; Gasser, R.D.

    1997-09-01

    The DEBRIS Late Phase Melt Progression Model is an assembly of models, embodied in a computer code, which is designed to treat late-phase melt progression in dry rubble (or debris) regions that can form as a consequence of a severe core uncover accident in a commercial light water nuclear reactor. The approach is fully two-dimensional, and incorporates a porous medium modeling framework together with conservation and constitutive relationships to simulate the time-dependent evolution of such regions as various physical processes act upon the materials. The objective of the code is to accurately model these processes so that the late-phase melt progression that would occur in different hypothetical severe nuclear reactor accidents can be better understood and characterized. In this report the models and correlations incorporated and used within the current version of DEBRIS are described. These include the global conservation equations solved, heat transfer and fission heating models, melting and refreezing models (including material interactions), liquid and solid relocation models, gas flow and pressure field models, and the temperature and compositionally dependent material properties employed. The specific models described here have been used in the experiment design analysis of the Phebus FPT-4 debris-bed fission-product release experiment. An earlier DEBRIS code version was used to analyze the MP-1 and MP-2 late-phase melt progression experiments conducted at Sandia National Laboratories for the US Nuclear Regulatory Commission.

  11. Exploration of cloud computing late start LDRD #149630 : Raincoat. v. 2.1.

    SciTech Connect (OSTI)

    Echeverria, Victor T.; Metral, Michael David; Leger, Michelle A.; Gabert, Kasimir Georg; Edgett, Patrick Garrett; Thai, Tan Q.

    2010-09-01

    This report contains documentation from an interoperability study conducted under the Late Start LDRD 149630, Exploration of Cloud Computing. A small late-start LDRD from last year resulted in a study (Raincoat) on using Virtual Private Networks (VPNs) to enhance security in a hybrid cloud environment. Raincoat initially explored the use of OpenVPN on IPv4 and demonstrates that it is possible to secure the communication channel between two small 'test' clouds (a few nodes each) at New Mexico Tech and Sandia. We extended the Raincoat study to add IPSec support via Vyatta routers, to interface with a public cloud (Amazon Elastic Compute Cloud (EC2)), and to be significantly more scalable than the previous iteration. The study contributed to our understanding of interoperability in a hybrid cloud.

  12. Enforcement Policy Statement: Treatment of Late-Arriving Goods Due to West

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Treatment of Late-Arriving Goods Due to West Coast Port Closure February 27, 2015 Closures at 29 West Coast marine ports in February 2015 due to a labor dispute have resulted in significant delays for certain goods entering the United States through those ports, including covered products and equipment subject to DOE energy or water conservation standards. Covered products and equipment subject to energy or water conservation standards must meet the standard(s) that are effective on the date

  13. TESTING THE METAL OF LATE-TYPE KEPLER PLANET HOSTS WITH IRON-CLAD METHODS

    SciTech Connect (OSTI)

    Mann, Andrew W.; Hilton, Eric J.; Gaidos, Eric; Kraus, Adam

    2013-06-10

    It has been shown that F, G, and early K dwarf hosts of Neptune-sized planets are not preferentially metal-rich. However, it is less clear whether the same holds for late K and M dwarf planet hosts. We report metallicities of Kepler targets and candidate transiting planet hosts with effective temperatures below 4500 K. We use new metallicity calibrations to determine [Fe/H] from visible and near-infrared spectra. We find that the metallicity distribution of late K and M dwarfs monitored by Kepler is consistent with that of the solar neighborhood. Further, we show that hosts of Earth- to Neptune-sized planets have metallicities consistent with those lacking detected planets and rule out a previously claimed 0.2 dex offset between the two distributions at 6{sigma} confidence. We also demonstrate that the metallicities of late K and M dwarfs hosting multiple detected planets are consistent with those lacking detected planets. Our results indicate that multiple terrestrial and Neptune-sized planets can form around late K and M dwarfs with metallicities as low as 0.25 solar. The presence of Neptune-sized planets orbiting such low-metallicity M dwarfs suggests that accreting planets collect most or all of the solids from the disk and that the potential cores of giant planets can readily form around M dwarfs. The paucity of giant planets around M dwarfs compared to solar-type stars must be due to relatively rapid disk evaporation or a slower rate of planet accretion, rather than insufficient solids to form a core.

  14. On the late-time behavior of tracer test breakthrough curves

    SciTech Connect (OSTI)

    HAGGERTY,ROY; MCKENNA,SEAN A.; MEIGS,LUCY C.

    2000-06-12

    The authors investigated the late-time (asymptotic) behavior of tracer test breakthrough curves (BTCs) with rate-limited mass transfer (e.g., in dual or multi-porosity systems) and found that the late-time concentration, c, is given by the simple expression: c = t{sub ad} (c{sub 0}g {minus} m{sub 0}{partial_derivative}g/{partial_derivative}t), for t >> t{sub ad} and t{sub a} >> t{sub ad} where t{sub ad} is the advection time, c{sub 0} is the initial concentration in the medium, m{sub 0} is the 0th moment of the injection pulse; and t{sub a} is the mean residence time in the immobile domain (i.e., the characteristic mass transfer time). The function g is proportional to the residence time distribution in the immobile domain, the authors tabulate g for many geometries, including several distributed (multirate) models of mass transfer. Using this expression they examine the behavior of late-time concentration for a number of mass transfer models. One key results is that if rate-limited mass transfer causes the BTC to behave as a power-law at late-time (i.e., c {approximately} t{sup {minus}k}), then the underlying density function of rate coefficients must also be a power-law with the form a{sup k{minus}}, as a {r_arrow}0. This is true for both density functions of first-order and diffusion rate coefficients. BTCs with k < 3 persisting to the end of the experiment indicate a mean residence time longer than the experiment and possibly infinite, and also suggest an effective rate coefficient that is either undefined or changes as a function of observation time. They apply their analysis to breakthrough curves from Single-Well Injection-Withdrawal tests at the Waste Isolation Pilot Plant, New Mexico.

  15. Ruptured Aortic Aneurysm From Late Type II Endoleak Treated by Transarterial Embolization

    SciTech Connect (OSTI)

    Gunasekaran, Senthil; Funaki, Brian Lorenz, Jonathan

    2013-02-15

    Endoleak is the most common complication after endovascular aneurysm repair. The most common type of endoleak, a type II endoleak, typically follows a benign course and is only treated when associated with increasing aneurysm size. In this case report, we describe a ruptured abdominal aortic aneurysm due to a late, type II endoleak occurring 10 years after endovascular aneurysm repair that was successfully treated by transarterial embolization.

  16. Confirmation of a late Oligocene-early Miocene age of the Deseadan Salla Beds of Bolivia

    SciTech Connect (OSTI)

    Naeser, C.W.; McKee, E.H.; Johnson, N.M.; MacFadden, B.J.

    1987-11-01

    Three new fission-track (zircon) and four new K-Ar (biotite) dates corroborate a late Oligocene-early Miocene age (22-28 Ma) for the Salla Beds of Bolivia. These ages contrast markedly with the previously accepted age of about 35 Ma for these strata and their contained faunas, and recasts of order and chronology of interchange between New World and Old World mammals.

  17. Late Cenozoic paleomagnetism and chronology of Andean basins of Bolivia: Evidence for possible oroclinal bending

    SciTech Connect (OSTI)

    MacFadden, B.J. ); Anaya, F.; Perez, H. ); Naeser, C.W. ); Zeitler, P.K. ); Campbell, K.E. Jr. )

    1990-07-01

    New paleomagnetic and radioisotopic data are reported from two late Tertiary high-elevation, non-marine basins in the eastern Cordillera of Bolivia. (1) Quebrada Honda, located at 22{degree}S lat., consists of a 300 m thick section containing abundant Santacrucian or Friasian (middle Miocene) fossil mammals. This locality is constrained by mean {sup 40}K/{sup 40}Ar ages of 12.83 {plus minus} 0.11 Ma and 11.96 {plus minus} 0.11 Ma, and the local magnetostratigraphy is correlated to chrons C5AA through C5A on the Magnetic Polarity Time Scale (MPTS). The fossil mammals from Quebrada Honda have an extrapolated age of about 13.0 to 12.7 Ma. (2) Micana, located at 17{degree}S lat., consists of a 205 m thick section containing late Miocene fossil mammals, including a megatheriid sloth and the tiny mesothere Microtypotherium cf. M. choquecotense. The locality is constrained by a fission-track age determination of 6.9 {plus minus} 1.1 Ma, and the local magnetostratigraphy is correlated to Chron 7 on the MPTS. The fossil mammals from this section have an extrapolated age of about 7.3 to 7.4 Ma. In conjunction with two other published data sets (Ocros, 13{degree}S, and Salla, 17{degree}S), these late Tertiary Andean localities indicate counterclockwise rotation at 13{degree}S, negligible rotation at 17{degree}S, and clockwise rotation at 22{degree}S. These data could represent local small-block rotations on a scale greater than about 6 km{sup 2}. However, these data are also consistent with a model of late Neogene bending of the Bolivian Orocline.

  18. The origin of the plateau and late rebrightening in the afterglow of GRB 120326A

    SciTech Connect (OSTI)

    Hou, S. J.; Lu, J. F.; Geng, J. J.; Wang, K.; Huang, Y. F.; Dai, Z. G.; Wu, X. F.

    2014-04-20

    GRB 120326A is an unusual gamma-ray burst (GRB) that has a long plateau and a very late rebrightening in both X-ray and optical bands. The similar behavior of the optical and X-ray light curves suggests that they may share a common origin. The long plateau starts at several hundred seconds and ends at tens of thousands of seconds, and the peak time of the late rebrightening is about 30,000 s. We analyze the energy injection model by means of numerical and analytical solutions, considering both the wind environment and the interstellar medium environment for GRB afterglows. We particularly study the influence of the injection starting time, ending time, stellar wind density (or density of the circumburst environment), and injection luminosity on the shape of the afterglow light curves, respectively. In the wind model, we find that the light curve is largely affected by the parameters and that there is a 'bump' in the late stage. In the wind environment, we found that the longer the energy is injected, the more obvious the rebrightening will be. We also find that the peak time of the bump is determined by the stellar wind density. We use the late continuous injection model to interpret the unusual afterglow of GRB 120326A. The model fits the observational data well; however, we find that the timescale of the injection must be higher than 10,000 s, which implies that the timescale of the central engine activity must also be more than 10,000 s. This information can give useful constraints on the central engines of GRBswe consider a newborn millisecond pulsar with a strong magnetic field to be the central engine. On the other hand, our results suggest that the circumburst environment of GRB 120326A is very likely a stellar wind.

  19. Structure and geologic history of late Cenozoic Eel River basin, California

    SciTech Connect (OSTI)

    Clarke, S.H. Jr.

    1988-03-01

    The Eel River basin formed as a late Cenozoic forearc basin floored by late Mesozoic and early Cenozoic allochthonous terranes (central and coastal belts of the Franciscan complex). Regionally, basement rocks are unconformably overlain on land by a sedimentary sequence as much as about 4200 m thick that comprises the Bear River Formation (early and middle Miocene) and the Wildcat Group (late Miocene to middle Pleistocene) and offshore by broadly coeval upper Tertiary and Quaternary deposits as much as 3300 m thick. Offshore, the southern part of the basin is typified by the seaward extensions of youthful northeast-dipping thrust and reverse faults and northwest-trending anticlines. The latest period of deformation in this part of the basin began during the middle Pleistocene and probably reflects north-northwestward migration of the Mendocino triple junction and encroachment of the Pacific plate. Farther north, the western basin margin and adjacent upper continental slope are separated from the axial part of the offshore basin by a narrow zone of north-northwest-trending, right-stepping en echelon folds. These folds indicate that northeast-southwest compression characteristic of the southern part of the basin is accompanied toward the north by right-lateral shear between the accretionary complex to the west and the basin to the east. The northeastern margin of the offshore basin is cut by north to north-northwest-trending high-angle reverse faults that vertically offset basement rocks as much as 1300 m, west side down. These faults, which may merge northward, coincide with older terrane boundaries and locally show evidence of late Cenozoic reactivation with possible right-lateral slip.

  20. Late Permian to mid-Cretaceous carbonate platform along the passive margin of the southeastern Mediterranean

    SciTech Connect (OSTI)

    Derin, B.; Garfunkel, Z.

    1988-08-01

    Starting from the Late Permian and throughout most of the Mesozoic, up to 5 km of shallow-water carbonates formed in a subsiding belt along the northern fringe of the Arabo-African continent, passing inland into thinner and clastic-rich sections. This sedimentation pattern was established in the Late Permian and evolved in several distinct stages that depended on global oscillations of sea level and local tectonic events. In Middle Triassic to early Liassic times, several pulses of faulting and magmatism, interpreted as rifting, occurred along the subsiding belt of carbonate deposition and produced a passive continental margin. Tectonic activity ended by the Roarcian, and since then a rather uniform shallow-water carbonate shelf formed. It was delimited by shoals of high-energy sediments and fringing reefs, inland of which low-energy carbonate muds and sometimes dolomite accumulated. By the Late Jurassic a more than 1.5 km-high continental slope developed, separating the shallow-water domain from a starved deep-water basin. In latest Jurassic and earliest Cretaceous time the activity of an intraplate hot spot caused extensive magmatism, uplifting, and erosion. The eroded material formed a thick sediment body in front of the continental slope. Since late Valanginian time, renewed regional subsidence and a rise in sea level led to a new phase of carbonate deposition over a wide shallow-water shelf. This was fringed by an accentuated continental slope covered by a basinward-thinning wedge-shaped apron of calciclastic sediments. This region was terminated by Senonian and later deformation related to plate collision in the Alpine orogenic belt.

  1. Clues to the nature of SN 2009ip from photometric and spectroscopic evolution to late times

    SciTech Connect (OSTI)

    Graham, M. L. [Astronomy Department, University of California, Berkeley, CA 94720 (United States); Sand, D. J. [Physics Department, Texas Tech University, Lubbock, TX 79409 (United States); Valenti, S.; Howell, D. A.; Parrent, J. [Las Cumbres Observatory Global Telescope Network, Goleta, CA 93117 (United States); Halford, M.; Zaritsky, D. [Astronomy Department, University of Arizona, Tucson, AZ 85721 (United States); Bianco, F. [Department of Physics, New York University, 4 Washington Place, New York, NY 10003 (United States); Rest, A. [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Dilday, B., E-mail: melissagraham@berkeley.edu [North Idaho College, 1000 W. Garden Avenue, Coeur d'Alene, ID 83814 (United States)

    2014-06-01

    We present time series photometric and spectroscopic data for the transient SN 2009ip from the start of its outburst in 2012 September until 2013 November. These data were collected primarily with the new robotic capabilities of the Las Cumbres Observatory Global Telescope Network, a specialized facility for time domain astrophysics, and includes supporting high-resolution spectroscopy from the Southern Astrophysical Research Telescope, Kitt Peak National Observatory, and Gemini Observatory. Based on our nightly photometric monitoring, we interpret the strength and timing of fluctuations in the light curve as interactions between fast-moving ejecta and an inhomogeneous circumstellar material (CSM) produced by past eruptions of this massive luminous blue variable (LBV) star. Our time series of spectroscopy in 2012 reveals that, as the continuum and narrow H? flux from CSM interactions declines, the broad component of H? persists with supernova (SN)-like velocities that are not typically seen in LBVs or SN impostor events. At late times, we find that SN 2009ip continues to decline slowly, at ? 0.01 mag day{sup 1}, with small fluctuations in slope similar to Type IIn supernovae (SNe IIn) or SN impostors but no further LBV-like activity. The late-time spectrum features broad calcium lines similar to both late-time SNe and SN impostors. In general, we find that the photometric and spectroscopic evolution of SN 2009ip is more similar to SNe IIn than either continued eruptions of an LBV star or SN impostors but we cannot rule out a nonterminal explosion. In this context, we discuss the implications for episodic mass loss during the late stages of massive star evolution.

  2. Alternative pre-mRNA splicing switches modulate gene expression in late erythropoiesis

    SciTech Connect (OSTI)

    Yamamoto, Miki L.; Clark, Tyson A.; Gee, Sherry L.; Kang, Jeong-Ah; Schweitzer, Anthony C.; Wickrema, Amittha; Conboy, John G.

    2009-02-03

    Differentiating erythroid cells execute a unique gene expression program that insures synthesis of the appropriate proteome at each stage of maturation. Standard expression microarrays provide important insight into erythroid gene expression but cannot detect qualitative changes in transcript structure, mediated by RNA processing, that alter structure and function of encoded proteins. We analyzed stage-specific changes in the late erythroid transcriptome via use of high-resolution microarrays that detect altered expression of individual exons. Ten differentiation-associated changes in erythroblast splicing patterns were identified, including the previously known activation of protein 4.1R exon 16 splicing. Six new alternative splicing switches involving enhanced inclusion of internal cassette exons were discovered, as well as 3 changes in use of alternative first exons. All of these erythroid stage-specific splicing events represent activated inclusion of authentic annotated exons, suggesting they represent an active regulatory process rather than a general loss of splicing fidelity. The observation that 3 of the regulated transcripts encode RNA binding proteins (SNRP70, HNRPLL, MBNL2) may indicate significant changes in the RNA processing machinery of late erythroblasts. Together, these results support the existence of a regulated alternative pre-mRNA splicing program that is critical for late erythroid differentiation.

  3. Modeling Study of the Effect of Anthropogenic Aerosols on Late Spring Drought in South China

    SciTech Connect (OSTI)

    Hu, Ning; Liu, Xiaohong

    2013-10-01

    In this study, the mechanisms underlying the decadal variability of late spring precipitation in south China are investigated using the latest version 1 of Community Earth System Model (CESM1). We aim to unravel the effects of different climate forcing agents, such as aerosols and greenhouse gases (GHGs), on the decadal variation of precipitation with transient experiments from pre-industry (for year 1850) to present-day (for year 2000). Our results reveal that: (1) CESM1 can reproduce the climatological features of atmospheric circulation and precipitation for the late spring in south China; (2) Only simulations including the forcing of anthropogenic aerosols can reproduce the observed decreasing trend of late spring precipitation from 1950-2000 in south China; (3) Aerosols affect the decadal change of precipitation mainly by altering the large scale atmospheric circulation, and to a less extent by increasing the lower-tropospheric stability to inhibit the convective precipitation; and (4) In comparison, other climate forcing agents, such as GHGs, have much smaller effects on the decadal change of spring precipitation in south China. Key words: precipitation, aerosols, climate change, south China, Community Earth System Model

  4. A paleoclimatic simulation of the Late Permian greenhouse world and its consequences

    SciTech Connect (OSTI)

    Moore, G.T.; Jacobson, S.R.; Hayashida, D.N. )

    1991-03-01

    Sea-floor spreading assembled all the major cratonic blocks into a single supercontinent once in the Phanerozoic Eon. This unique Late Permian crustal tectonic event produced Pangaea and an enormous oceanic basin volume that dropped sea level to a global lowstand unrivaled in the Phanerozoic. Two paleoclimatic simulations using a numerical three-dimensional general circulation model tested changes in the greenhouse effect. The authors conclude that for a simulation to fit the Late Permian geologic record, the paleoatmosphere must contain an enhanced greenhouse gas effect. A third simulation tested changes of paleogeography in southern Pangaea (Gondwana) that did not appreciably alter the harsh continental paleoclimate. The simulated paleoclimatic changes provide extraordinarily warm ocean and atmosphere, and a significant reduction in continental rainfall and runoff. These conditions inevitably lead to more aridity and less vegetation on land, gradually reduce the delivery of vital nutrients from continental sources to marine margins, systematically liberate CO{sub 2} dissolved in ocean water, and incrementally increase stress on marine and terrestrial biotas. These consequences severely disrupted rates of oxygen and carbon cycling. Their quantitative paleoclimatic simulation is consistent with distributions of red beds, evaporites, coals, marine shelf areas, seawater isotope trends, and paleontologic originations and extinctions. Thus, the Pangaean plate assembly probably triggered an inexorable sequence of geophysical, geochemical, and biological events that forced an elevated greenhouse effect in the Late Permian, nearly annihilating the Phanerozoic biota.

  5. Eolian evidence for climatic fluctuations during the Late Pleistocene and Holocene in Wyoming

    SciTech Connect (OSTI)

    Gaylord, D.R.

    1985-01-01

    Evaluation of eolian features, particularly sand dunes, in the Ferris-Lost Solider area of south-central Wyoming demonstrates the dynamic character of late Pleistocene and Holocene climatic fluctuations in a high altitude, intermontane basin. Directly- and indirectly-dated stratigraphic, sedimentary, and geomorphic evidence documents recurrent late Quaternary eolian activity as well as the timing and severity of episodic aridity during the Altithermal. Eolian activity in the Ferris-Lost Solider area began under cool and arid conditions by the late Pleistocene. Radiocarbon-dated dune and interdune strata reveal that Holocene sand dune building at Ferris-Lost Solider peaked between ca. 7660 and 4540 years b.p. The first phase of dune building was the most extensive and lasted until ca. 6460 years b.p. Warm, persistently arid conditions during this time favored active dunes with slipfaces, even in historically well-vegetated locales subject to high water tables. Increased effective moisture from ca. 6460 to 5940 years b.p. promoted dune stabilizing vegetation; but renewed dune building, lasting until ca. 4540 years b.p., followed this climatic moderation. Subsequent dune and interdune deposits reveal a return to climatic conditions where only sporadic and localized dune reactivations have interrupted overall dune stability. The most significant recent reactivation, probably associated with a regional decrease in effective moisture, occurred ca. 290 years b.p.

  6. The late endosome/lysosome-anchored p18-mTORC1 pathway controls terminal maturation of lysosomes

    SciTech Connect (OSTI)

    Takahashi, Yusuke; Nada, Shigeyuki; Mori, Shunsuke; Soma-Nagae, Taeko; Oneyama, Chitose; Okada, Masato

    2012-01-27

    Highlights: Black-Right-Pointing-Pointer p18 is a membrane adaptor that anchors mTORC1 to late endosomes/lysosomes. Black-Right-Pointing-Pointer We examine the role of the p18-mTORC1 pathway in lysosome biogenesis. Black-Right-Pointing-Pointer The loss of p18 causes accumulation of intact late endosomes by arresting lysosome maturation. Black-Right-Pointing-Pointer Inhibition of mTORC1 activity with rapamycin phenocopies the defects of p18 loss. Black-Right-Pointing-Pointer The p18-mTORC1 pathway plays crucial roles in the terminal maturation of lysosomes. -- Abstract: The late endosome/lysosome membrane adaptor p18 (or LAMTOR1) serves as an anchor for the mammalian target of rapamycin complex 1 (mTORC1) and is required for its activation on lysosomes. The loss of p18 causes severe defects in cell growth as well as endosome dynamics, including membrane protein transport and lysosome biogenesis. However, the mechanisms underlying these effects on lysosome biogenesis remain unknown. Here, we show that the p18-mTORC1 pathway is crucial for terminal maturation of lysosomes. The loss of p18 causes aberrant intracellular distribution and abnormal sizes of late endosomes/lysosomes and an accumulation of late endosome specific components, including Rab7, RagC, and LAMP1; this suggests that intact late endosomes accumulate in the absence of p18. These defects are phenocopied by inhibiting mTORC1 activity with rapamycin. Loss of p18 also suppresses the integration of late endosomes and lysosomes, resulting in the defective degradation of tracer proteins. These results suggest that the p18-mTORC1 pathway plays crucial roles in the late stages of lysosomal maturation, potentially in late endosome-lysosome fusion, which is required for processing of various macromolecules.

  7. Late Mesozoic crustal extension and rifting on the western edge of the Parana Basin, Paraguay

    SciTech Connect (OSTI)

    DeGraff, J.M.

    1985-01-01

    Geophysical and geological evidence indicates that the western edge of the Parana basin in Paraguay was a site of NE-SW directed crustal extension during late Mesozoic time. Major zones of normal faulting in south-eastern Paraguay trend northwesterly on average, and mafic dikes of probable late Mesozoic age have similar orientations. At least two NW-trending zones of tectonic subsidence, each over 200 km long, are now recognized in eastern Paraguay. Most alkalic rocks of south-eastern Paraguay are concentrated along this rift, and occur as simple to composite stocks and ring complexes composed of rocks ranging from foid-syenite to essexite. NW-trending, lamprophyric to phonolitic dikes are associated with some alkalic complexes. The southern zone, located about 125 km southwest, is a composite tectonic basin about 60 km wide and nearly devoid of alkalic rocks. The timing of crustal extension and rifting in eastern Paraguay is largely based on isotopic ages of associated alkalic rocks, which cluster between 150 and 100 Ma (latest Jurassic to mid-Cretaceous). Geologic evidence for the age of faulting and subsidence is consistent with this age range; tectonic depressions were being filled in late Cretaceous to early Cenozoic time. The age range of alkalic rocks in Paraguay contain that of the Serra Geral basalts and spans the time when South America Separated from Africa. This suggests that alkalic activity and crustal extension in eastern Paraguay are grossly related to the Serra Geral extrusive event, and were a manifestation of the breakup of South America and Africa far from the site of final separation.

  8. Growth in global oil inventories slows, drawdown in stocks expected in late 2017

    U.S. Energy Information Administration (EIA) Indexed Site

    Growth in global oil inventories slows, drawdown in stocks expected in late 2017 The growth in global oil inventories is expected to slow in response to stronger growth in world oil demand, with inventories now expected to be drawn down during the second half of next year. In its new monthly forecast, the U.S. Energy Information Administration said oil inventories will grow by just under 1 million barrels per day this year. Inventories will continue to grow during the first half of 2017 though

  9. IDENTIFYING NEARBY, YOUNG, LATE-TYPE STARS BY MEANS OF THEIR CIRCUMSTELLAR DISKS

    SciTech Connect (OSTI)

    Schneider, Adam; Song, Inseok; Melis, Carl; Zuckerman, B.; Bessell, Mike E-mail: song@physast.uga.edu E-mail: ben@astro.ucla.edu

    2012-10-01

    It has recently been shown that a significant fraction of late-type members of nearby, very young associations (age {approx}<10 Myr) display excess emission at mid-IR wavelengths indicative of dusty circumstellar disks. We demonstrate that the detection of mid-IR excess emission can be utilized to identify new nearby, young, late-type stars including two definite new members ('TWA 33' and 'TWA 34') of the TW Hydrae Association (TWA). Both new TWA members display mid-IR excess emission in the Wide-field Infrared Survey Explorer catalog and they show proper motion and youthful spectroscopic characteristics-namely, H{alpha} emission, strong lithium absorption, and low surface gravity features consistent with known TWA members. We also detect mid-IR excess-the first unambiguous evidence of a dusty circumstellar disk-around a previously identified UV-bright, young, accreting star (2M1337) that is a likely member of the Lower-Centaurus Crux region of the Scorpius-Centaurus Complex.

  10. LATE-TIME OBSERVATIONS OF GRB 080319B: JET BREAK, HOST GALAXY, AND ACCOMPANYING SUPERNOVA

    SciTech Connect (OSTI)

    Tanvir, N. R.; O'Brien, P. T.; Wiersema, K.; Starling, R. L. C.; Rol, E.; Levan, A. J.; Svensson, K.; Fruchter, A. S.; Granot, J.; Jakobsson, P.; Fynbo, J.; Hjorth, J.; Curran, P. A.; Burrows, D. N.; Genet, F.

    2010-12-10

    The Swift-discovered GRB 080319B was by far the most distant source ever observed at naked-eye brightness, reaching a peak apparent magnitude of 5.3 at a redshift of z = 0.937. We present our late-time optical (Hubble Space Telescope, Gemini, and Very Large Telescope) and X-ray (Chandra) observations, which confirm that an achromatic break occurred in the power-law afterglow light curve at {approx}11 days post-burst. This most likely indicates that the gamma-ray burst (GRB) outflow was collimated, which for a uniform jet would imply a total energy in the jet E{sub jet} {approx}> 10{sup 52} erg. Our observations also show a late-time excess of red light, which is well explained if the GRB was accompanied by a supernova (SN), similar to those seen in some other long-duration GRBs. The latest observations are dominated by light from the host and show that the GRB took place in a faint dwarf galaxy (r(AB) {approx} 27.0, rest frame M{sub B} {approx} -17.2). This galaxy is small even by the standards of other GRB hosts, which is suggestive of a low-metallicity environment. Intriguingly, the properties of this extreme event-a small host and bright SN-are entirely typical of the very low luminosity bursts such as GRB 980425 and GRB 060218.

  11. Probabilistic accident consequence uncertainty analysis -- Late health effects uncertain assessment. Volume 2: Appendices

    SciTech Connect (OSTI)

    Little, M.P.; Muirhead, C.R.; Goossens, L.H.J.; Kraan, B.C.P.; Cooke, R.M.; Harper, F.T.; Hora, S.C.

    1997-12-01

    The development of two new probabilistic accident consequence codes, MACCS and COSYMA, was completed in 1990. These codes estimate the consequence from the accidental releases of radiological material from hypothesized accidents at nuclear installations. In 1991, the US Nuclear Regulatory Commission and the Commission of the European Communities began cosponsoring a joint uncertainty analysis of the two codes. The ultimate objective of this joint effort was to systematically develop credible and traceable uncertainty distributions for the respective code input variables. A formal expert judgment elicitation and evaluation process was identified as the best technology available for developing a library of uncertainty distributions for these consequence parameters. This report focuses on the results of the study to develop distribution for variables related to the MACCS and COSYMA late health effects models. This volume contains appendices that include (1) a summary of the MACCS and COSYMA consequence codes, (2) the elicitation questionnaires and case structures, (3) the rationales and results for the expert panel on late health effects, (4) short biographies of the experts, and (5) the aggregated results of their responses.

  12. Lung Irradiation Increases Mortality After Influenza A Virus Challenge Occurring Late After Exposure

    SciTech Connect (OSTI)

    Manning, Casey M.; Johnston, Carl J.; Reed, Christina K.; Lawrence, B. Paige; Williams, Jacqueline P.; Finkelstein, Jacob N.

    2013-05-01

    Purpose: To address whether irradiation-induced changes in the lung environment alter responses to a viral challenge delivered late after exposure but before the appearance of late lung radiation injury. Methods and Materials: C57BL/6J mice received either lung alone or combined lung and whole-body irradiation (0-15 Gy). At 10 weeks after irradiation, animals were infected with 120 HAU influenza virus strain A/HKx31. Innate and adaptive immune cell recruitment was determined using flow cytometry. Cytokine and chemokine production and protein leakage into the lung after infection were assessed. Results: Prior irradiation led to a dose-dependent failure to regain body weight after infection and exacerbated mortality, but it did not affect virus-specific immune responses or virus clearance. Surviving irradiated animals displayed a persistent increase in total protein in bronchoalveolar lavage fluid and edema. Conclusions: Lung irradiation increased susceptibility to death after infection with influenza virus and impaired the ability to complete recovery. This altered response does not seem to be due to a radiation effect on the immune response, but it may possibly be an effect on epithelial repair.

  13. Upper Permian fluviolacustrine deposits of southern Africa and the late Permian climate southern Gondwana

    SciTech Connect (OSTI)

    Yemane, K. . Dept. of Geology Bryn Mawr Coll., PA . Dept. of Geology)

    1993-03-01

    Upper Permian-age fluviolacustrine deposits are widespread throughout southern Africa. In the southern part of the subcontinent, where deposition took place in foreland basin settings, the sequences are thicker and fluvial-dominated whereas, lacustrine-dominated deposits accumulated in settings of low relief, broad warping and mild faulting at the northern end. The geographic extent and lateral correlatability of these deposits suggest the existence of concurrent, perhaps interconnected, giant lakes within major fluvial frameworks throughout the subcontinent, thousands of miles inland from the sea. This period of major lake development within fluvial depositional settings suggests climatic conditions that sustained a uniquely wet continental environment, deep in the heart of the Gondwanan supercontinent. Simulations based on various general circulation and energy balance climate models predict extreme seasonal temperatures and aridity for Gondwana at the palaeolatitudes of southern Africa during the Late Permian. On the other hand, distribution of climate-sensitive rocks, palynologic and palaeobotanic data and vertebrate fossils, coroborate the temperature climate documented by sedimentologic studies. The erroneous modeling results may have arisen from the fact that the models do not employ palaeogeographies that accommodate the existence of the vast lakes and rivers of Gondwana. The Late Permian palaeogeography of series of giant lakes within major fluvial frameworks would have had considerable influences on the regional climate. This suggests that it is imperative that numerical modeling studies incorporate accurate palaeogeographies, constructed based on available geological data, in order to recreate past climates with acceptable degree of accuracy.

  14. Stratigraphic evidence for late Quaternary dune activity near Hudson on the Piedmont of northern Colorado

    SciTech Connect (OSTI)

    Forman, S.L.; Maat, P. (Univ. of Colorado, Boulder (USA))

    1990-08-01

    Stabilized dune fields are common features near Hudson, on the Piedmont of northern Colorado. Exposures in dune and interdune sites expose a sequence of eolian sediments and paleosols that record a complex history of eolian activity during the late Quaternary. Radiocarbon and thermoluminescence age estimates on A horizons buried by eolian sand indicate that dunes were reactivated sometime between 7 and 9 ka. On the basis of morphology of surface soils, the dunes were most recently stabilized <3 ka. At present that are no data to indicate if there were multiple periods of dune movement and stabilization during the Holocene. The penultimate pre-Holocene dune-forming episode probably terminated ca. 13 ka and may be coincident with the Pinedale glaciation. The stratigraphy at interdune sites shows at least two eolian depositional events prior to the penultimate event; they were separated by periods of pedogenesis, one of which may have exceeded 40 ka. This analysis indicates that dunes in northern Colorado were active during both cold-arid and warn-arid periods in the late Quaternary.

  15. Proxy late Holocene climatic record deduced from northwest Alaska beach ridges

    SciTech Connect (OSTI)

    Mason, O.K.; Jordan, J.W.

    1992-03-01

    A climatically sensitive, oscillatory pattern of progradation and erosion is revealed in late Holocene accretionary sand ridge and barrier island complexes of Seward Peninsula, northwest Alaska. Archaeological and geological radiocarbon dates constrain the chronology for the Cape Espenberg beach ridge plain and the Shishmaref barrier islands, 50 km to the southwest. Cape Espenberg, the depositional sink for the northeastward longshore transport system, contains the oldest sedimentary deposits: 3700 +/- 90 B.P. (B-23170) old grass from a paleosol in a low dune. The oldest date on the Shishmaref barrier islands is 1550 +/- 70 B.P. (B-23183) and implies that the modern barrier is a comparatively recent phenomenon. Late Holocene sedimentation along the Seward Peninsula varied between intervals of rapid progradation and erosion. Rapid progradation predominated from 4000-3300 B.P. and from 2000-1200 B.P., with the generation of low beach ridges without dunes, separated by wide swales. During erosional periods higher dunes built atop beach ridges: as between 3300-2000 B.P. and intermittently from 1000 B.P. to the present. Dune formation correlates with the Neoglacial and Little Ice Age glacial advances and increased alluviation in northern and central Alaska, while rapid progradation is contemporaneous with warmer intervals of soil and/or, peat formation atop alluvial terraces, dated to 4000-3500 and 2000-1000 B.P.

  16. Hypopharyngeal Dose Is Associated With Severe Late Toxicity in Locally Advanced Head-and-Neck Cancer: An RTOG Analysis

    SciTech Connect (OSTI)

    Machtay, Mitchell; Moughan, Jennifer; Farach, Andrew; University of Texas Health Science Center Martin-O'Meara, Elizabeth; Galvin, James; Thomas Jefferson University, Philadelphia, Pennsylvania ; Garden, Adam S.; Weber, Randal S.; Cooper, Jay S.; Forastiere, Arlene; Ang, K. Kian

    2012-11-15

    Purpose: Concurrent chemoradiation therapy (CCRT) for squamous cell carcinoma of the head and neck (SCCHN) increases local tumor control but at the expense of increased toxicity. We recently showed that several clinical/pretreatment factors were associated with the occurrence of severe late toxicity. This study evaluated the potential relationship between radiation dose delivered to the pharyngeal wall and toxicity. Methods and Materials: This was an analysis of long-term survivors from 3 previously reported Radiation Therapy Oncology Group (RTOG) trials of CCRT for locally advanced SCCHN (RTOG trials 91-11, 97-03, and 99-14). Severe late toxicity was defined in this secondary analysis as chronic grade 3-4 pharyngeal/laryngeal toxicity and/or requirement for a feeding tube {>=}2 years after registration and/or potential treatment-related death (eg, pneumonia) within 3 years. Radiation dosimetry (2-dimensional) analysis was performed centrally at RTOG headquarters to estimate doses to 4 regions of interest along the pharyngeal wall (superior oropharynx, inferior oropharynx, superior hypopharynx, and inferior hypopharynx). Case-control analysis was performed with a multivariate logistic regression model that included pretreatment and treatment potential factors. Results: A total of 154 patients were evaluable for this analysis, 71 cases (patients with severe late toxicities) and 83 controls; thus, 46% of evaluable patients had a severe late toxicity. On multivariate analysis, significant variables correlated with the development of severe late toxicity, including older age (odds ratio, 1.062 per year; P=.0021) and radiation dose received by the inferior hypopharynx (odds ratio, 1.023 per Gy; P=.016). The subgroup of patients receiving {<=}60 Gy to the inferior hypopharynx had a 40% rate of severe late toxicity compared with 56% for patients receiving >60 Gy. Oropharyngeal dose was not associated with this outcome. Conclusions: Severe late toxicity following CCRT is

  17. ELEMENTAL ABUNDANCES IN THE EJECTA OF OLD CLASSICAL NOVAE FROM LATE-EPOCH SPITZER SPECTRA

    SciTech Connect (OSTI)

    Helton, L. Andrew; Vacca, William D.; Gehrz, Robert D.; Woodward, Charles E.; Shenoy, Dinesh P.; Wagner, R. Mark; Evans, Aneurin; Krautter, Joachim; Schwarz, Greg J.; Starrfield, Sumner

    2012-08-10

    We present Spitzer Space Telescope mid-infrared IRS spectra, supplemented by ground-based optical observations, of the classical novae V1974 Cyg, V382 Vel, and V1494 Aql more than 11, 8, and 4 years after outburst, respectively. The spectra are dominated by forbidden emission from neon and oxygen, though in some cases, there are weak signatures of magnesium, sulfur, and argon. We investigate the geometry and distribution of the late time ejecta by examination of the emission line profiles. Using nebular analysis in the low-density regime, we estimate lower limits on the abundances in these novae. In V1974 Cyg and V382 Vel, our observations confirm the abundance estimates presented by other authors and support the claims that these eruptions occurred on ONe white dwarfs (WDs). We report the first detection of neon emission in V1494 Aql and show that the system most likely contains a CO WD.

  18. Late-time structure of the Bunch-Davies de Sitter wavefunction

    SciTech Connect (OSTI)

    Anninos, Dionysios; Anous, Tarek; Freedman, Daniel Z.; Konstantinidis, George

    2015-11-30

    We examine the late time behavior of the Bunch-Davies wavefunction for interacting light fields in a de Sitter background. We use perturbative techniques developed in the framework of AdS/CFT, and analytically continue to compute tree and loop level contributions to the Bunch-Davies wavefunction. We consider self-interacting scalars of general mass, but focus especially on the massless and conformally coupled cases. We show that certain contributions grow logarithmically in conformal time both at tree and loop level. We also consider gauge fields and gravitons. The four-dimensional Fefferman-Graham expansion of classical asymptotically de Sitter solutions is used to show that the wavefunction contains no logarithmic growth in the pure graviton sector at tree level. Finally, assuming a holographic relation between the wavefunction and the partition function of a conformal field theory, we interpret the logarithmic growths in the language of conformal field theory.

  19. Tumor histology and location predict deep nuclei toxicity: Implications for late effects from focal brain irradiation

    SciTech Connect (OSTI)

    Plaga, Alexis; Shields, Lisa B.E.; Sun, David A.; Vitaz, Todd W.; Spalding, Aaron C.

    2012-10-01

    Normal tissue toxicity resulting from both disease and treatment is an adverse side effect in the management of patients with central nervous system malignancies. We tested the hypothesis that despite these improvements, certain tumors place patients at risk for neurocognitive, neuroendocrine, and neurosensory late effects. Defining patient groups at risk for these effects could allow for development of preventive strategies. Fifty patients with primary brain tumors underwent radiation planning with magnetic resonance imaging scan and computed tomography datasets. Organs at risk (OAR) responsible for neurocognitive, neuroendocrine, and neurosensory function were defined. Inverse-planned intensity-modulated radiation therapy was optimized with priority given to target coverage while penalties were assigned to exceeding normal tissue tolerances. Tumor laterality, location, and histology were compared with OAR doses, and analysis of variance was performed to determine the significance of any observed correlation. The ipsilateral hippocampus exceeded dose limits in frontal (74%), temporal (94%), and parietal (100%) lobe tumor locations. The contralateral hippocampus was at risk in the following tumor locations: frontal (53%), temporal (83%), or parietal (50%) lobe. Patients with high-grade glioma were at risk for ipsilateral (88%) and contralateral (73%) hippocampal damage (P <0.05 compared with other histologies). The pituitary gland and hypothalamus exceeded dose tolerances in patients with pituitary tumors (both 100%) and high-grade gliomas (50% and 75%, P <0.05 compared with other histologies), respectively. Despite application of modern radiation therapy, certain tumor locations and histologies continue to place patients at risk for morbidity. Patients with high-grade gliomas or tumors located in the frontal, temporal, or parietal lobes are at risk for neurocognitive decline, likely because of larger target volumes and higher radiation doses. Data from this study

  20. Great Basin semi-arid woodland dynamics during the late quaternary

    SciTech Connect (OSTI)

    Wigand, P.E.; Hemphill, M.L.; Sharpe, S.E.

    1995-09-01

    Semi-arid woodlands have dominated the middle elevations of Great Basin mountain ranges during the Holocene where subalpine woodlands prevailed during the Pleistocene. Ancient woodrat middens, and in a few cases pollen records indicate in the late Pleistocene and early Holocene woodland history lowered elevation of subalpine woodland species. After a middle Holocene retrenchment at elevations in excess of 500 meters above today, Juniper-dominated semi-arid woodland reached its late Holocene maximum areal extent during the Neoglacial (2 to 4 ka). These records, along with others indicate contracting semi-arid woodland after the Neoglacial about 1.9 ka. Desert shrub community expansion coupled with increased precariousness of wetland areas in the southern Great Basin between 1.9 and 1.5 ka coincide with shrinking wet-lands in the west-central and northern Great Basin. Coincident greater grass abundance in northern Great Basin sagebrush steppe, reaching its maximum between 1.5 and 1.2 ka, corresponds to dramatic increases in bison remains in the archaeological sites of the northern Intermontane West. Pollen and woodrat midden records indicate that this drought ended about 1.5 ka. Succeeding ameliorating conditions resulted in the sudden northward and downward expansion of pinon into areas that had been dominated by juniper during the Neoglacial. Maximum areal extent of pinon dominated semi-arid woodland in west-central Nevada was centered at 1.2 ka. This followed by 100 years the shift in dominance from juniper to pinon in southern Nevada semi-arid woodlands. Great Basin woodlands suffered from renewed severe droughts between .5 to .6 ka. Effectively wetter conditions during the {open_quotes}Little Ice Age{close_quotes} resulted in re-expansion of semi-arid woodland. Activities related to European settlement in the Great Basin have modified prehistoric factors or imposed new ones that are affecting woodland response to climate.

  1. Early-Late Heterobimetallic Complexes Linked by Phosphinoamide Ligands. Tuning Redox Potentials and Small Molecule Activation

    SciTech Connect (OSTI)

    Thomas, Christine M.

    2015-08-01

    Recent attention in the chemical community has been focused on the energy efficient and environmentally benign conversion of abundant small molecules (CO2, H2O, etc.) to useful liquid fuels. This project addresses these goals by examining fundamental aspects of catalyst design to ultimately access small molecule activation processes under mild conditions. Specifically, Thomas and coworkers have targetted heterobimetallic complexes that feature metal centers with vastly different electronic properties, dictated both by their respective positions on the periodic table and their coordination environment. Unlike homobimetallic complexes featuring identical or similar metals, the bonds between metals in early/late heterobimetallics are more polarized, with the more electron-rich late metal center donating electron density to the more electron-deficient early metal center. While metal-metal bonds pose an interesting strategy for storing redox equivalents and stabilizing reactive metal fragments, the polar character of metal-metal bonds in heterobimetallic complexes renders these molecules ideally poised to react with small molecule substrates via cleavage of energy-rich single and double bonds. In addition, metal-metal interactions have been shown to dramatically affect redox potentials and promote multielectron redox activity, suggesting that metal-metal interactions may provide a mechanism to tune redox potentials and access substrate reduction/activation at mild overpotentials. This research project has provided a better fundamental understanding of how interactions between transition metals can be used as a strategy to promote and/or control chemical transformations related to the clean production of fuels. While this project focused on the study of homogeneous systems, it is anticipated that the broad conclusions drawn from these investigations will be applicable to heterogeneous catalysis as well, particularly on heterogeneous processes that occur at interfaces in

  2. Groundwater flow, late cementation, and petroleum accumulation the Permian Lyons Sandstone, Denver basin

    SciTech Connect (OSTI)

    Lee, M.K.; Bethke, C.M. )

    1994-02-01

    The gray diagenetic facies of the Permian Lyons Sandstone, associated with all known petroleum accumulations in the formation, formed late in the history of the Denver basin as an alteration product of the formation's red facies. The red facies that makes up most of the sandstone contains iron oxide coating, quartz overgrowths and calcite cements. The gray facies, which occurs locally in the deep basin, is distinguished by pore-filling dolomite and anhydrite cements and by a lack of iron oxide and calcite. The dolomite and anhydrite cements overlie bitumen that was deposited by migrating oil, and hence formed after oil was first generated in the basin, late in the Cretaceous or early in the Tertiary. The isotopic composition of oxygen in the dolomite ranges to such light values that the cement must have formed deep in the basin in the presence of meteoric water. The gray facies likely formed in a regime of groundwater flow resulting from Laramide uplift of the Front Range during the Tertiary. In our model, saline groundwater flowed eastward through the Pennsylvanian Fountain Formation and then upwelled along the basin axis, where is discharged into the Lyons Sandstone. The saline water mixed with more dilute groundwater in the Lyons, driving a reaction that dissolved calcite and, by a common-ion effect, precipitated dolomite and anhydrite. The facies' gray color resulted from reduction of ferric oxide in the presence of migrating oil or the Fountain brine. Underlying source beds by this time had begun to generate petroleum, which migrated by buoyancy into the Lyons. The association of the gray facies with petroleum accumulations can be explained if the Fountain brines discharged across aquitards along the same fractures that transmitted oil. As petroleum accumulated in the Lyons, the newly formed cements prevented continued migration, as is observed in shallower strata, by sealing oil into the reservoirs from which it is produced today. 77 refs., 16 figs., 5 tabs.

  3. WE-D-BRE-03: Late Toxicity Following Photon Or Proton Radiotherapy in Patients with Brain Tumors

    SciTech Connect (OSTI)

    Munbodh, R; Ding, X; Yin, L; Anamalayil, S; Dorsey, J; Lustig, R; Alonso-Basanta, M

    2014-06-15

    Purpose: To identify indicators of Late Grade 3 (LG3) toxicity, late vision and hearing changes in patients treated for primary brain tumors with photon (XRT) or proton radiotherapy (PRT). Methods: We retrospectively reviewed 102 patients who received brain XRT or PRT to doses of 54 or 59.6 Gy in daily fractions of 1.8–2 Gy. Of the 80 patients (34 XRT, 39 PRT and 7 both modalities) reviewed for indicators of LG3 toxicity, 25 developed LG3 toxicity 90 to 500 days after radiotherapy completion. 55 patients had less than LG3 toxicity > 500 days after treatment. In that time, late vision and hearing changes were seen in 44 of 75 and 25 of 78 patients, respectively. The correlation between late toxicity and prescription dose, planning target volume (PTV) size, and doses to the brainstem, brain, optic chiasm, optic nerves, eyes and cochlea was evaluated. A two-tailed Fisher's exact test and Wilcoxon rank sum test were used for the statistical analysis for XRT, PRT and all patients combined. Results: Exceeding the 54 Gy-5% dose-volume brainstem constraint, but not the optic structure constraints, was significantly correlated (p < 0.05) with late vision changes in all three groups. Exceeding maximum and mean cochlear doses of 45 and 30 Gy, respectively, was a significant indicator of hearing changes (p < 0.05) in PRT patients and all patients combined. In a sub-group of 52 patients in whom the brain was contoured, the absolute brain volume receiving ≤ 50 Gy and > 60 Gy was significantly larger in patients with LG3 toxicity for all patients combined (p < 0.05). Prescription dose, brainstem dose and PTV volume were not correlated to LG3 toxicity. Conclusion: Our results indicate the importance of minimizing the brain volume irradiated, and brainstem and cochlea doses to reduce the risk of late toxicities following brain radiotherapy.

  4. Very late nonfatal consequences of fractionated TBI in children undergoing bone marrow transplant

    SciTech Connect (OSTI)

    Faraci, Maura; Cohen, Amnon; Lanino, Edoardo; Sacco, Oliviero; Cabria, Manlio; De Marco, Riccardo; Stella, Gilberto; Dallorso, Sandro; Vitale, Vito; Dini, Giorgio

    2005-12-01

    Purpose: To describe long-term late consequences in children who received total body irradiation (TBI) for hematopoietic stem cell transplantation 10 years earlier. Methods and Materials: A cohort of 42 children treated with TBI between 1985 and 1993, still alive at least 10 years after fractionated TBI (FTBI), was evaluated. Twenty-five patients received FTBI at 330 cGy/day for 3 days (total dose 990 cGy), whereas 17 children were administered fractions of 200 cGy twice daily for 3 days (total dose 1200 cGy). Twenty-seven patients received autologous and 16 allogeneic hematopoietic stem cell transplantation. Median age at TBI was 6.3 years, and 18.4 years at most recent follow-up. Results: Cataract was diagnosed in 78% of patients after a median of 5.7 years. Hypothyroidism was detected in 12%, whereas thyroid nodules were observed in 60% of our population after a median interval of 10.2 years. Patients treated with 990 cGy developed thyroid nodules more frequently than those treated with 1200 cGy (p = 0.0002). Thyroid carcinoma was diagnosed in 14% of the total population. Females who received FTBI after menarche more frequently developed temporary ovarian dysfunction than those treated before menarche, but cases of persistent ovarian dysfunction did not differ between the two groups. Indirect signs of germinal testicular dysfunction were detected in 87% of males. Restrictive pulmonary disease was observed in 74% of patients. Osteochondroma was found in 29% of patients after a median interval of 9.2 years. This latter complication appeared more frequently in patients irradiated before the age of 3 years (p < 0.001). Conclusions: This study shows that late effects that are likely permanent, although not fatal, are frequent in survivors 10 years after TBI. However, some of the side effects observed shortly after TBI either disappeared or remained unchanged without signs of evolution. Monitoring is recommended to pursue secondary prevention strategies and counseling

  5. EVALUATING SHORT-TERM CLIMATE VARIABILITY IN THE LATE HOLOCENE OF THE NORTHERN GREAT PLAINS

    SciTech Connect (OSTI)

    Joseph H. Hartman

    1999-09-01

    This literature study investigated methods and areas to deduce climate change and climate patterns, looking for short-term cycle phenomena and the means to interpret them. Many groups are actively engaged in intensive climate-related research. Ongoing research might be (overly) simplified into three categories: (1) historic data on weather that can be used for trend analysis and modeling; (2) detailed geological, biological (subfossil), and analytical (geochemical, radiocarbon, etc.) studies covering the last 10,000 years (about since last glaciation); and (3) geological, paleontological, and analytical (geochemical, radiometric, etc.) studies over millions of years. Of importance is our ultimate ability to join these various lines of inquiry into an effective means of interpretation. At this point, the process of integration is fraught with methodological troubles and misconceptions about what each group can contribute. This project has met its goals to the extent that it provided an opportunity to study resource materials and consider options for future effort toward the goal of understanding the natural climate variation that has shaped our current civilization. A further outcome of this project is a proposed methodology based on ''climate sections'' that provides spatial and temporal correlation within a region. The method would integrate cultural and climate data to establish the climate history of a region with increasing accuracy with progressive study and scientific advancement (e. g., better integration of regional and global models). The goal of this project is to better understand natural climatic variations in the recent past (last 5000 years). The information generated by this work is intended to provide better context within which to examine global climate change. The ongoing project will help to establish a basis upon which to interpret late Holocene short-term climate variability as evidenced in various studies in the northern Great Plains, northern

  6. Predictors of Severe Acute and Late Toxicities in Patients With Localized Head-and-Neck Cancer Treated With Radiation Therapy

    SciTech Connect (OSTI)

    Meyer, Francois; Fortin, Andre; Wang, Chang Shu; Liu, Geoffrey

    2012-03-15

    Purpose: Radiation therapy (RT) causes acute and late toxicities that affect various organs and functions. In a large cohort of patients treated with RT for localized head and neck cancer (HNC), we prospectively assessed the occurrence of RT-induced acute and late toxicities and identified characteristics that predicted these toxicities. Methods and Materials: We conducted a randomized trial among 540 patients treated with RT for localized HNC to assess whether vitamin E supplementation could improve disease outcomes. Adverse effects of RT were assessed using the Radiation Therapy Oncology Group Acute Radiation Morbidity Criteria during RT and one month after RT, and the Radiation Therapy Oncology Group/European Organization for Research and Treatment of Cancer Late Radiation Morbidity Scoring Scheme at six and 12 months after RT. The most severe adverse effect among the organs/tissues was selected as an overall measure of either acute or late toxicity. Grade 3 and 4 toxicities were considered as severe. Stepwise multivariate logistic regression models were used to identify all independent predictors (p < 0.05) of acute or late toxicity and to estimate odds ratios (OR) for severe toxicity with their 95% confidence intervals (CI). Results: Grade 3 or 4 toxicity was observed in 23% and 4% of patients, respectively, for acute and late toxicity. Four independent predictors of severe acute toxicity were identified: sex (female vs. male: OR = 1.72, 95% confidence interval [CI]: 1.06-2.80), Karnofsky Performance Status (OR = 0.67 for a 10-point increment, 95% CI: 0.52-0.88), body mass index (above 25 vs. below: OR = 1.88, 95% CI: 1.22-2.90), TNM stage (Stage II vs. I: OR = 1.91, 95% CI: 1.25-2.92). Two independent predictors were found for severe late toxicity: female sex (OR = 3.96, 95% CI: 1.41-11.08) and weight loss during RT (OR = 1.26 for a 1 kg increment, 95% CI: 1.12-1.41). Conclusions: Knowledge of these predictors easily collected in a clinical setting could help

  7. Novel, highly expressed late nodulin gene (LjNOD16) from Lotus japonicus

    SciTech Connect (OSTI)

    Kapranov, P.; Bruijn, F.J. de; Szczyglowski, K.

    1997-04-01

    We have isolated a Lotus japonicus cDNA corresponding to a highly abundant, late nodule-specific RNA species that encodes a polypeptide with a predicted molecular mass of 15.6 kD. The protein and its corresponding gene were designated NIj16 and LjNOD16, respectively. LjNOD16 was found to be expressed only in the infected cells of L. japonicus nodules. Related DNA sequences could be identified in the genomes of both Glycine max and Medicago sativa. In the latter, a homologous mRNA species was detected in the nodules. Unlike LiNOD16, its alfalfa homologs appear to represent low-abundance mRNA species. However, the proteins corresponding to the LjNOD16 and its alfalfa homolog could be detected at similar levels in nodules but not in roots of both legume species. The predicted amino acid sequence analysis of nodulin NIj16 revealed the presence of a long {alpha}-helical region and a positively charged C terminus. The former domain has a very high propensity to form a coiled-coil type structure, indicating that nodulin NIj16 may interact with an as-yet-unidentified protein target(s) in the nodule-infected cells. Homology searches revealed no significant similarities to any known sequences in the databases, with the exception of two related, anonymous Arabidopsis expressed sequence tags.

  8. Characterization of a Messer – The late-Medieval single-edged sword of Central Europe

    SciTech Connect (OSTI)

    Fajfar, Peter; Medved, Jožef; Klančnik, Grega; Lazar, Tomaž; Nečemer, Marijan; Mrvar, Primož

    2013-12-15

    Metallurgical characterization of a sword blade fragments dating from the second half of the 15th century found in central Slovenia was performed in order to determine its chemical composition, microstructure, microhardness, and to obtain insight into the methods of manufacture of a late-medieval Messer sword. As the artefact was broken, examinations were limited to six very small fragments that were allowed to be removed from the cutting edge, core and the back of the blade. Light optical microscopy, scanning electron microscopy, energy dispersive X-ray spectroscopy, energy dispersive X-ray fluorescence spectrometry, differential scanning calorimetry, thermodynamics approach and Vickers micro-hardness tests were employed to analyze the microstructure and mechanical properties. The results show that the sword was manufactured from a single wrought iron billet. The surface of the sword was carburized. No evidence of quenching was found. The ferritic microstructure is concentrated in the core, and the pearlitic in the outer layer of the blade. All metal fragments contained non-metallic inclusions that were derived mostly from slag and some from hammer scale. - Highlights: • A metallurgical characterization of a medieval sword blade has been performed. • The carbon content decreased from the surface to the core of the blade. • The dominant microstructure in the outer layer is pearlite and in the core is ferrite. • The presence of lump shaped and elongated non-metallic inclusions was observed. • The sword was manufactured from a single wrought iron billet.

  9. Overexpression of Late Embryogenesis Abundant 14 enhances Arabidopsis salt stress tolerance

    SciTech Connect (OSTI)

    Jia, Fengjuan Qi, Shengdong Li, Hui Liu, Pu Li, Pengcheng Wu, Changai Zheng, Chengchao Huang, Jinguang

    2014-11-28

    Highlights: It is the first time to investigate the biological function of AtLEA14 in salt stress response. AtLEA14 enhances the salt stress tolerance both in Arabidopsis and yeast. AtLEA14 responses to salt stress by stabilizing AtPP2-B11, an E3 ligase, under normal or salt stress conditions. - Abstract: Late embryogenesis abundant (LEA) proteins are implicated in various abiotic stresses in higher plants. In this study, we identified a LEA protein from Arabidopsis thaliana, AtLEA14, which was ubiquitously expressed in different tissues and remarkably induced with increased duration of salt treatment. Subcellular distribution analysis demonstrated that AtLEA14 was mainly localized in the cytoplasm. Transgenic Arabidopsis and yeast overexpressing AtLEA14 all exhibited enhanced tolerance to high salinity. The transcripts of salt stress-responsive marker genes (COR15a, KIN1, RD29B and ERD10) were overactivated in AtLEA14 overexpressing lines compared with those in wild type plants under normal or salt stress conditions. In vivo and in vitro analysis showed that AtLEA14 could effectively stabilize AtPP2-B11, an important E3 ligase. These results suggested that AtLEA14 had important protective functions under salt stress conditions in Arabidopsis.

  10. The abundance properties of nearby late-type galaxies. I. The data

    SciTech Connect (OSTI)

    Pilyugin, L. S.; Grebel, E. K.; Kniazev, A. Y. E-mail: grebel@ari.uni-heidelberg.de

    2014-06-01

    We investigate the oxygen and nitrogen abundance distributions across the optical disks of 130 nearby late-type galaxies using around 3740 published spectra of H II regions. We use these data in order to provide homogeneous abundance determinations for all objects in the sample, including H II regions in which not all of the usual diagnostic lines were measured. Examining the relation between N and O abundances in these galaxies we find that the abundances in their centers and at their isophotal R {sub 25} disk radii follow the same relation. The variation in N/H at a given O/H is around 0.3 dex. We suggest that the observed spread in N/H may be partly caused by the time delay between N and O enrichment and the different star formation histories in galaxies of different morphological types and dimensions. We study the correlations between the abundance properties (central O and N abundances, radial O and N gradients) of a galaxy and its morphological type and dimension.

  11. Gold deposits in the late Archaean Nzega-Igunga greenstone belt, central plateau of tanzania

    SciTech Connect (OSTI)

    Feiss, P.G.; Siyomana, S.

    1985-01-01

    2.2 m oz of gold have been produced, since 1935, from late Archaean (2480-2740 Ma) greenstone belts of the Central Plateau, Tanzania. North and east of Nzega (4/sup 0/12'S, 3/sup 0/11'E), 18% of the exposed basement, mainly Dodoman schists and granites, consists of metavolcanics and metasediments of the Nyanzian and Kavirondian Series. Four styles of mineralization are observed. 1. Stratabound quartz-gold veins with minor sulfides. Host rocks are quartz porphyry, banded iron formation (BIF), magnetite quartzite, and dense, cherty jasperite at the Sekenke and Canuck mines. The Canuck veins are on strike from BIF's in quartz-eye porphyry of the Igusule Hills. 2. Stratabound, disseminated gold in coarse-grained, crowded feldspar porphyry with lithic fragments and minor pyrite. At Bulangamilwa, the porphyry is conformable with Nyanzian-aged submarine (.) greenstone, volcanic sediment, felsic volcanics, and sericite phyllite. The deposits are on strike with BIF of the Wella Hills, which contains massive sulfide with up to 15% Pb+Zn. 3. Disseminated gold in quartz-albite metasomes in Nyanzian greenstones. At Kirondatal, alteration is associated with alaskites and feldspar porphyry dikes traceable several hundred meters into post-Dodoman diorite porphyry. Gold is with pyrite, arsenopyrite, pyrrhotite, minor chalcopyrite, and sphalerite as well as tourmalinite and silica-cemented breccias. 4. Basal Kavirondian placers in metaconglomerates containing cobbles and boulders of Dodoman and Nyanzian rocks several hundred meters up-section from the stratabound, disseminated mineralization at Bulangamilwa.

  12. MOA-2010-BLG-328Lb: A sub-Neptune orbiting very late M dwarf?

    SciTech Connect (OSTI)

    Furusawa, K.; Abe, F.; Itow, Y.; Masuda, K.; Matsubara, Y.; Udalski, A.; Sumi, T.; Bennett, D. P.; Bond, I. A.; Ling, C. H.; Gould, A.; Jørgensen, U. G.; Snodgrass, C.; Prester, D. Dominis; Albrow, M. D.; Botzler, C. S.; Freeman, M.; Chote, P.; Harris, P.; Fukui, A. E-mail: liweih@astro.ucla.edu E-mail: rzellem@lpl.arizona.edu; Collaboration: MOA Collaboration; OGLE Collaboration; μFUN Collaboration; MiNDSTEp Consortium; RoboNet Collaboration; PLANET Collaboration; and others

    2013-12-20

    We analyze the planetary microlensing event MOA-2010-BLG-328. The best fit yields host and planetary masses of M {sub h} = 0.11 ± 0.01 M {sub ☉} and M {sub p} = 9.2 ± 2.2 M {sub ⊕}, corresponding to a very late M dwarf and sub-Neptune-mass planet, respectively. The system lies at D {sub L} = 0.81 ± 0.10 kpc with projected separation r = 0.92 ± 0.16 AU. Because of the host's a priori unlikely close distance, as well as the unusual nature of the system, we consider the possibility that the microlens parallax signal, which determines the host mass and distance, is actually due to xallarap (source orbital motion) that is being misinterpreted as parallax. We show a result that favors the parallax solution, even given its close host distance. We show that future high-resolution astrometric measurements could decisively resolve the remaining ambiguity of these solutions.

  13. Diagenetic features of Trenton Limestone in northern Indiana: petrographic evidence for Late (Mesogenetic) Dolostone

    SciTech Connect (OSTI)

    Fara, D.R.

    1986-08-01

    Three conventional cores of the entire Trenton section were examined in detail by in-depth visual description, analysis of more than 250 thin sections, scanning electron microscopy, and x-ray diffraction. The cores are located in the northern half of Indiana where they span the major dolostone pinch-out that is the trap for the prolific Trenton oil and gas field. The Trenton Limestone is completely dolomitized in northern Indiana. Dolostone abundance decreases to the south where the dolostone is restricted to the upper few feet of the formation. Two major types of dolostone are recognized. The top 5-20 ft of the Trenton cores consists of medium crystalline nonporous xenotopic ferroan dolostone. Mesogenetic dewatering of the overlying Maquoketa shale is the proposed dolomitizing mechanisms for this ferroan dolostone cap. Below the ferroan dolostone cap in northern Indiana is coarsely crystalline dolostone, which consists of thin intercalated subfacies of porous idiotopic and nonporous xenotopic dolostone. This is the dominant dolostone type and is the reservoir in the Trenton field. The coarsely crystalline dolostone postdates the ferroan dolostone cap, chert nodule formation, and initial pressure solution. Therefore, this dolostone is considered to have formed relatively late in the diagenetic history of the Trenton under mesogenetic conditions. In the northernmost core, nearly all of the secondary dolomitic porosity is plugged by poikilotopic gypsum and minor amounts of calcite and celestite. Other diagenetic features observed in Trenton are also discussed, including silicification, ferroan calcite cement, upper Trenton contact formation, hardgrounds, and pressure solution.

  14. Synsedimentary tectonics in Late Cretaceous-Early Tertiary pelagic basin of northern Apennines, Italy

    SciTech Connect (OSTI)

    Montanari, A.; Chan, L.S.; Alvarez, W.

    1987-05-01

    The sequence of Upper Cretaceous-Lower Tertiary pelagic limestones in the Umbria-Marches Apennines of Italy have recorded, with remarkable continuity, the geologic history of an epeiric sea on the eastern continental margin of the Ligurian Ocean during a time of widespread tectonism in the western Tethys domain. Sedimentary facies and paleocurrent analyses indicate that intrabasinal depocenters and structural highs have formed in response to extensional tectonic movements which started to affect the central part of the paleobasin in the early Turonian. The topography of the paleobasin was probably controlled by a complex pattern of buried fault blocks formed during the passive margin phase of the western Tethys and then reactivated in the Turonian after a prolonged time (Aptian to Cenomanian) of tectonic quiescence. Calcareous turbidites essentially made of remobilized pelagic mud were generated on the newly formed intrabasinal slopes and deposited in the adjacent depocenters. Conspicuous sedimentary events such as maxima in turbiditic deposition and soft-sediment slumps in these intrabasinal depocenters are attributed to major syndepositional earthquakes of regional extent. A detailed event-stratigraphy based on these sedimentary features indicates that the level of syndepositional tectonic activity reached a peak in the late Maastrichtian-early Paleocene and rapidly diminished in the Eocene.

  15. KELT-3b: A HOT JUPITER TRANSITING A V = 9.8 LATE-F STAR

    SciTech Connect (OSTI)

    Pepper, Joshua; Siverd, Robert J.; Stassun, Keivan G.; Cargile, Phillip A.; Dhital, Saurav; Beatty, Thomas G.; Gaudi, B. Scott; Eastman, Jason; Fulton, Benjamin J.; Collins, Karen; Latham, David W.; Bieryla, Allyson; Calkins, Michael L.; Esquerdo, Gilbert A.; Berlind, Perry; Buchhave, Lars A.; Jensen, Eric L. N.; Manner, Mark; Penev, Kaloyan; Crepp, Justin R.; and others

    2013-08-10

    We report the discovery of KELT-3b, a moderately inflated transiting hot Jupiter with a mass of 1.477{sub -0.067}{sup +0.066} M{sub J}, radius of 1.345 {+-} 0.072 R{sub J}, and an orbital period of 2.7033904 {+-} 0.000010 days. The host star, KELT-3, is a V = 9.8 late F star with M{sub *} = 1.278{sub -0.061}{sup +0.063} M{sub sun}, R{sub *} = 1.472{sub -0.067}{sup +0.065} R{sub sun}, T{sub eff}= 6306{sub -49}{sup +50} K, log (g) = 4.209{sub -0.031}{sup +0.033}, and [Fe/H] = 0.044{sub -0.082}{sup +0.080}, and has a likely proper motion companion. KELT-3b is the third transiting exoplanet discovered by the KELT survey, and is orbiting one of the 20 brightest known transiting planet host stars, making it a promising candidate for detailed characterization studies. Although we infer that KELT-3 is significantly evolved, a preliminary analysis of the stellar and orbital evolution of the system suggests that the planet has likely always received a level of incident flux above the empirically identified threshold for radius inflation suggested by Demory and Seager.

  16. BUILDING LATE-TYPE SPIRAL GALAXIES BY IN-SITU AND EX-SITU STAR FORMATION

    SciTech Connect (OSTI)

    Pillepich, Annalisa; Madau, Piero; Mayer, Lucio

    2015-02-01

    We analyze the formation and evolution of the stellar components in ''Eris'', a 120pc resolution cosmological hydrodynamic simulation of a late-type spiral galaxy. The simulation includes the effects of a uniform UV background, a delayed-radiative-cooling scheme for supernova feedback, and a star formation recipe based on a high gas density threshold. It allows a detailed study of the relative contributions of ''in-situ'' (within the main host) and ''ex-situ'' (within satellite galaxies) star formation to each major Galactic component in a close Milky Way analog. We investigate these two star-formation channels as a function of galactocentric distance, along different lines of sight above and along the disk plane, and as a function of cosmic time. We find that: (1) approximately 70% of today's stars formed in-situ; (2) more than two thirds of the ex-situ stars formed within satellites after infall; (3) the majority of ex-situ stars are found today in the disk and in the bulge; (4) the stellar halo is dominated by ex-situ stars, whereas in-situ stars dominate the mass profile at distances ? 5 kpc from the center at high latitudes; and (5) approximately 25% of the inner, r ? 20 kpc, halo is composed of in-situ stars that have been displaced from their original birth sites during Eris' early assembly history.

  17. The Araucaria project. The distance to the small Magellanic Cloud from late-type eclipsing binaries

    SciTech Connect (OSTI)

    Graczyk, Dariusz; Pietrzyński, Grzegorz; Gieren, Wolfgang; Pilecki, Bogumił; Villanova, Sandro; Gallenne, Alexandre; Thompson, Ian B.; Konorski, Piotr; Udalski, Andrzej; Soszyński, Igor; Górski, Marek; Suchomska, Ksenia; Karczmarek, Paulina; Kudritzki, Rolf-Peter; Bresolin, Fabio

    2014-01-01

    We present a distance determination to the Small Magellanic Cloud (SMC) based on an analysis of four detached, long-period, late-type eclipsing binaries discovered by the Optical Gravitational Lensing Experiment (OGLE) survey. The components of the binaries show negligible intrinsic variability. A consistent set of stellar parameters was derived with low statistical and systematic uncertainty. The absolute dimensions of the stars are calculated with a precision of better than 3%. The surface brightness-infrared color relation was used to derive the distance to each binary. The four systems clump around a distance modulus of (m – M) = 18.99 with a dispersion of only 0.05 mag. Combining these results with the distance published by Graczyk et al. for the eclipsing binary OGLE SMC113.3 4007, we obtain a mean distance modulus to the SMC of 18.965 ± 0.025 (stat.) ± 0.048 (syst.) mag. This corresponds to a distance of 62.1 ± 1.9 kpc, where the error includes both uncertainties. Taking into account other recent published determinations of the SMC distance we calculated the distance modulus difference between the SMC and the Large Magellanic Cloud equal to 0.458 ± 0.068 mag. Finally, we advocate μ{sub SMC} = 18.95 ± 0.07 as a new 'canonical' value of the distance modulus to this galaxy.

  18. Venezuelan equine encephalitis virus entry mechanism requires late endosome formation and resists cell membrane cholesterol depletion

    SciTech Connect (OSTI)

    Kolokoltsov, Andrey A.; Fleming, Elisa H.; Davey, Robert A. . E-mail: radavey@utmb.edu

    2006-04-10

    Virus envelope proteins determine receptor utilization and host range. The choice of receptor not only permits specific targeting of cells that express it, but also directs the virus into specific endosomal trafficking pathways. Disrupting trafficking can result in loss of virus infectivity due to redirection of virions to non-productive pathways. Identification of the pathway or pathways used by a virus is, thus, important in understanding virus pathogenesis mechanisms and for developing new treatment strategies. Most of our understanding of alphavirus entry has focused on the Old World alphaviruses, such as Sindbis and Semliki Forest virus. In comparison, very little is known about the entry route taken by more pathogenic New World alphaviruses. Here, we use a novel contents mixing assay to identify the cellular requirements for entry of a New World alphavirus, Venezuelan equine encephalitis virus (VEEV). Expression of dominant negative forms of key endosomal trafficking genes shows that VEEV must access clathrin-dependent endocytic vesicles for membrane fusion to occur. Unexpectedly, the exit point is different from Old World alphaviruses that leave from early endosomes. Instead, VEEV also requires functional late endosomes. Furthermore, unlike the Old World viruses, VEEV entry is insensitive to cholesterol sequestration from cell membranes and may reflect a need to access an endocytic compartment that lacks cholesterol. This indicates fundamental differences in the entry route taken by VEEV compared to Old World alphaviruses.

  19. FORMING REALISTIC LATE-TYPE SPIRALS IN A {Lambda}CDM UNIVERSE: THE ERIS SIMULATION

    SciTech Connect (OSTI)

    Guedes, Javiera; Madau, Piero [Department of Astronomy and Astrophysics, University of California, 1156 High Street, Santa Cruz, CA 95064 (United States); Callegari, Simone [Institute for Theoretical Physics, University of Zuerich, Winterthurerstrasse 190, CH-9057 Zuerich (Switzerland); Mayer, Lucio [Institute for Astronomy, ETH Zuerich, Wolgang-Pauli-Strasse 27, 8093 Zuerich (Switzerland)

    2011-12-01

    Simulations of the formation of late-type spiral galaxies in a cold dark matter ({Lambda}CDM) universe have traditionally failed to yield realistic candidates. Here we report a new cosmological N-body/smooth particle hydrodynamic simulation of extreme dynamic range in which a close analog of a Milky Way disk galaxy arises naturally. Named 'Eris', the simulation follows the assembly of a galaxy halo of mass M{sub vir} = 7.9 Multiplication-Sign 10{sup 11} M{sub Sun} with a total of N = 18.6 million particles (gas + dark matter + stars) within the final virial radius, and a force resolution of 120 pc. It includes radiative cooling, heating from a cosmic UV field and supernova explosions (blastwave feedback), a star formation recipe based on a high gas density threshold (n{sub SF} = 5 atoms cm{sup -3} rather than the canonical n{sub SF} = 0.1 atoms cm{sup -3}), and neglects any feedback from an active galactic nucleus. Artificial images are generated to correctly compare simulations with observations. At the present epoch, the simulated galaxy has an extended rotationally supported disk with a radial scale length R{sub d} = 2.5 kpc, a gently falling rotation curve with circular velocity at 2.2 disk scale lengths of V{sub 2.2} = 214 km s{sup -1}, an i-band bulge-to-disk ratio B/D = 0.35, and a baryonic mass fraction within the virial radius that is 30% below the cosmic value. The disk is thin, has a typical H I-to-stellar mass ratio, is forming stars in the region of the {Sigma}{sub SFR}-{Sigma}{sub HI} plane occupied by spiral galaxies, and falls on the photometric Tully-Fisher and the stellar-mass-halo-virial-mass relations. Hot (T > 3 Multiplication-Sign 10{sup 5} K) X-ray luminous halo gas makes up only 26% of the universal baryon fraction and follows a 'flattened' density profile {proportional_to}r{sup -1.13} out to r = 100 kpc. Eris appears then to be the first cosmological hydrodynamic simulation in which the galaxy structural properties, the mass budget in the

  20. Thermonuclear supernovae: probing magnetic fields by positrons and late-time IR line profiles

    SciTech Connect (OSTI)

    Penney, R.; Hoeflich, P. E-mail: rpenney@g.clemson.edu

    2014-11-01

    We show the importance of γ and positron transport for the formation of late-time spectra in Type Ia supernovae (SNe Ia). The goal is to study the imprint of magnetic fields (B) on late-time IR line profiles, particularly the [Fe II] feature at 1.644 μm, which becomes prominent two to three months after the explosion. As a benchmark, we use the explosion of a Chandrasekhar mass (M {sub Ch}) white dwarf (WD) and, specifically, a delayed detonation model that can reproduce the light curves and spectra for a Branch-normal SN Ia. We assume WDs with initial magnetic surface fields between 1 and 10{sup 9} G. We discuss large-scale dipole and small-scale magnetic fields. We show that positron transport effects must be taken into account for the interpretation of emission features starting at about one to two years after maximum light, depending on the size of B. The [Fe II] line profile and its evolution with time can be understood in terms of the overall energy input by radioactive decay and the transition from a γ-ray to a positron-dominated regime. We find that the [Fe II] line at 1.644 μm can be used to analyze the overall chemical and density structure of the exploding WD up to day 200 without considering B. At later times, positron transport and magnetic field effects become important. After about day 300, the line profile allows one to probe the size of the B-field. The profile becomes sensitive to the morphology of B at about day 500. In the presence of a large-scale dipole field, a broad line is produced in M {sub Ch} mass explosions that may appear flat-topped or rounded depending on the inclination at which the SN is observed. Small or no directional dependence of the spectra is found for small-scale B. We note that narrow-line profiles require central {sup 56}Ni as shown in our previous studies. Persistent broad-line, flat-topped profiles require high-density burning, which is the signature of a WD close to M {sub Ch}. Good time coverage is required to

  1. SUMMARY REPORT OF THE DOE DIRECT LIQUEFACTION PROCESS DEVELOPMENT CAMPAIGN OF THE LATE TWENTIETH CENTURY

    SciTech Connect (OSTI)

    F.P. Burke; S.D. Brandes; D.C. McCoy; R.A. Winschel; D. Gray; G. Tomlinson

    2001-07-01

    Following the petroleum price and supply disruptions of 1973, the U.S. government began a substantial program to fund the development of alternative fuels. Direct coal liquefaction was one of the potential routes to alternative fuels. The direct coal liquefaction program was funded at substantial levels through 1982, and at much lower levels thereafter. Those processes that were of most interest during this period were designed to produce primarily distillate fuels. By 1999, U.S. government funding for the development of direct coal liquefaction ended. Now that the end of this campaign has arrived, it is appropriate to summarize the process learnings derived from it. This report is a summary of the process learnings derived from the DOE direct coal liquefaction process development campaign of the late twentieth century. The report concentrates on those process development programs that were designed to produce primarily distillate fuels and were largely funded by DOE and its predecessors in response to the petroleum supply and price disruptions of the 1970s. The report is structured as chapters written by different authors on most of the major individual DOE-funded process development programs. The focus of the report is process learnings, as opposed to, say, fundamental coal liquefaction science or equipment design. As detailed in the overview (Chapter 2), DOE's direct coal liquefaction campaign made substantial progress in improving the process yields and the quality of the distillate product. Much of the progress was made after termination by 1983 of the major demonstration programs of the ''first generation'' (SRC-II, H-Coal, EDS) processes.

  2. Late Pleistocene landslide-dammed lakes along the Rio Grande, White Rock Canyon, New Mexico

    SciTech Connect (OSTI)

    Reneau, S.L.; Dethier, D.P.

    1996-11-01

    Massive slump complexes composed of Pliocene basaltic rocks and underlying Miocene and Pliocene sediments flank the Rio Grande along 16 km of northern White Rock Canyon, New Mexico. The toe area of at least one slump complex was active in the late Pleistocene, damming the Rio Grande at least four times during the period from 18 to 12 {sup 14}C ka and impounding lakes that extended 10-20 km upriver. Stratigraphic relationships and radiocarbon age constraints indicate that three separate lakes formed between 13.7 and 12.4 {sup 14}C ka. The age and dimensions of the ca. 12.4 ka lake are best constrained; it had an estimated maximum depth of {approx}30 m, a length of {approx}13 km, a surface area of {approx}2.7 km{sup 2}, and an initial volume of {approx}2.5 x 10{sup 7} m{sup 3}. The youngest landslide-dammed lakes formed during a period of significantly wetter regional climate, strongly suggesting that climate changes were responsible for reactivation of the slump complexes. We are not certain about the exact triggering mechanisms for these landslides, but they probably involved removal of lateral support due to erosion of the slope base by the Rio Grande during periods of exceptionally high flood discharge or rapid incision; increased pore pressures associated with higher water tables; higher seepage forces at sites of ground-water discharge; or some combination of these processes. Seismic shaking could also have contributed to triggering of some of the landslides, particularly if aided by wet antecedent conditions. 54 refs., 19 figs., 3 tabs.

  3. Ramu basin, Papua New Guinea: A record of late Miocene terrane collision

    SciTech Connect (OSTI)

    Cullen, A.B.

    1996-05-01

    The Ramu basin lies along a plate boundary where the Finisterre terrane is colliding with the Indo-Australian plate. Estimates for the age of initial collision range from early Miocene to middle Pliocene. Two unsuccessful wells (Keram 1 and Tsumba 1) drilled to basement and two-dimensional seismic data show that folded and faulted early to middle Miocene carbonates and clastics (the Wogamush sequence) are overlain by relatively undeformed Pliocene marine clastics (the Wewak sequence) along a regional unconformity. The pre-Pliocene section, which is at the crux of resolving the age of initial collision, has been correlated previously to the Finisterre terrane. Clastics within that section, derived from older terranes south of the basin, imply an early Miocene age for collision. I propose that Miocene sedimentary and volcanic rocks in the two wells are correlative with the Wogamush beds of the Maramuni arc. The Ramu basin can then be viewed as having a two-stage evolution. During the Miocene, the basin was part of the Maramuni arc, the polarity of which is unresolved. A collisional successor basin developed in the late Miocene as the Finisterre terrane (Adelbert block) collided with the arc. Thrust faults on the northeastern side of the basin, truncated by a regional unconformity, are interpreted to mark the suture of the Adelbert block. A northern earliest Pliocene sediment source for the basal Wewak sequence was probably the Finisterre terrane, but multiple source areas are inferred for the rest of that sequence. Middle Pliocene inversion of the basin`s northeastern flank, characterized by reverse faulting and forced folding, is attributed to plate boundary reorganization caused by rifting in the Bismarck Sea. The Ramu basin has numerous untested structures related to both collision and basin inversion. Gas-prone source rocks are present, but are largely immature. Reservoir and charge considerations place the Ramu basin in the very high risk sector for exploration.

  4. Similarities in shoreline response to Late Holocene lake-level variations in Lake Michigan

    SciTech Connect (OSTI)

    Thompson, T.A.; Baedke, S.J. )

    1992-01-01

    Beach ridges dating back to 2600 B.P. occur in embayments throughout Lake Michigan. Similarities in their geomorphic development are interpreted to be the product of three scales of lake-level variation. The largest of these embayments is roughly coincident with the Indiana shore of Lake Michigan known as the Toleston Beach. In the western part of the Toleston Beach, more than 150 beach ridges have formed in response to short-term variations in lake level occurring at a quasi-periodic interval of about 30 years. Bundles of five of these ridges merge eastward to form higher relief beach ridges that record an intermediate-term lake-level variation of about 150 years. Both the 30-year and 150-year lake-level events are superimposed on a longer term lake-level variation of about 600 years. Beach-ridge development in northern Lake Michigan reflects a similar response to late Holocene lake-level variations. For example, the southern embayment of the Platte Bay Unit of the Sleeping Bear Dunes National Lakeshore also contains a series of beach ridges that record three scales of lake-level variation. In this area, most of the beach ridges formed between 2600 and 1200 B.P., with individual ridges forming about every 29 years. Also recorded in this embayment are the time equivalent groupings of beach ridges every 150 and 600 years. Although embayments containing beach ridges in Lake Michigan may record different short-term lake-level variations in response to local depositional conditions within the embayment, the 150-year and 600-year variations appear to be represented throughout the lake. Relative lake-level curves for the Toleston Beach and the Platte Bay embayment are displaced by approximately 1.5 m. This displacement is accounted for under current models of isostasy for Lake Michigan.

  5. Climatic change and the planktonic foraminiferal species - coincidences in some Late Neogene clades

    SciTech Connect (OSTI)

    Malmgren, B.A.; Berggren, W.A.

    1985-01-01

    Planktonic foraminifera adjust their position in the water column through modifications in size, shape, and external ornamention (keel, costae, etc.); this is useful in exploiting new ecologic niches. Evolutionary change may be triggered by paleoceanographic change, for example, low sea level, often associated with cool climate, may result in enhanced vertical mixing in the upper water column, decrease in density stratification and available niches. Phyletic evolution is well documented in several clades of Late Neogene planktonic foraminifera. Accelerated or decelerated evolutionary rates in these clades may be due to change in selection pressure in response to changing paleoceanographic conditions. The latest Miocene was marked by low sea level and cool climate; the earliest Pliocene by higher sea level and warmer, more stable climate. In response, size (cross-sectional area) in the Globorotalia tumida clade trebled, test acquired thicker encrustation, ventral/dorsal height proportions changed; the keel was lost in the Globorotalia inflata clade, and chambers became rounded rather than conical; and supplementary apertures appeared in the Sphaeroidinellopsis-Sphaeroidinella clade. The beginning of gradually increasing conicality in the G. inflata clade, which continued to the Miocene-Pliocene boundary, coincided with falling sea level and depletion of delta/sup 13/C in sea water at about 6 ma. Lowered sea level and cooler climate in the middle Pliocene (3.2 Ma) may be responsible for a relatively rapid increase in frequency of supplementary apertures (from 20 to 100 %) in the Sphaeroidinellopsis-Sphaeroidinella clade. This event also coincided with a stepwise increase in benthonic delta/sup 18/O and a brief interval of increased planktonic delta/sup 18/O.

  6. Climate Change in Lowland Central America During the Late Deglacial and Early Holocene

    SciTech Connect (OSTI)

    Hillesheim, M B; Hodell, D A; Leyden, B W; Brenner, M; Curtis, J H; Anselmetti, F S; Ariztegui, D; Buck, D G; Guilderson, T P; Rosenmeier, M F; Schnurrenberger, D W

    2005-02-08

    The transition from arid glacial to moist early Holocene conditions represented a profound change in northern lowland Neotropical climate. Here we report a detailed record of changes in moisture availability during the latter part of this transition ({approx}11,250 to 7,500 cal yr BP) inferred from sediment cores retrieved in Lake Peten Itza, northern Guatemala. Pollen assemblages demonstrate that a mesic forest had been largely established by {approx}11,250 cal yr BP, but sediment properties indicate that lake level was more than 35 m below modern stage. From 11,250 to 10,350 cal yr BP, during the Preboreal period, lithologic changes in sediments from deep-water cores (>50 m below modern water level) indicate several wet-dry cycles that suggest distinct changes in effective moisture. Four dry events (designated PBE1-4) occurred at 11,200, 10,900, 10,700, and 10,400 cal yr BP and correlate with similar variability observed in the Cariaco Basin titanium record and glacial meltwater pulses into the Gulf of Mexico. After 10,350 cal yr BP, multiple sediment proxies suggest a shift to a more persistently moist early Holocene climate. Comparison of results from Lake Peten Itza with other records from the circum-Caribbean demonstrates a coherent climate response during the entire span of our record. Furthermore, lowland Neotropical climate during the late deglacial and early Holocene period appears to be tightly linked to climate change in the high-latitude North Atlantic. We speculate that the observed changes in lowland Neotropical precipitation were related to the intensity of the annual cycle and associated displacements in the mean latitudinal position of the Intertropical Convergence Zone and Azores-Bermuda high-pressure system. This mechanism operated on millennial-to-submillennial timescales and may have responded to changes in solar radiation, glacial meltwater, North Atlantic sea ice, and the Atlantic meridional overturning circulation (MOC).

  7. Geologic evolution of the Late Permian Capitan shelf margin, northern Delaware basin

    SciTech Connect (OSTI)

    Grover, G.A. )

    1991-03-01

    A two-phase model, based on outcrop and subsurface data rimming the northern half of the Delaware basin, characterizes the evolution of the late Guadalupian Capitan shelf margin, a margin that prograded up to 19 km basinward while an interval of over 700 m accumulated. Phase 1, during Seven Rivers shelf (early Capitan) deposition, accounts for 70-80% of the total progradation, over 50% of the total aggradation, and corresponds with shelf facies devoid of siliciclastics, emplacement of abundant carbonate debris on the slope and basin margin, and deposition of 50-70% of the Bell Canyon siliciclastic interval in the basin. The clastics bypassed the growing Capitan margin and were equally important to that of the allochthonous carbonate debris in filling accommodation space to facilitate progradation of the margin. The second phase, during Yates-Tansill (middle-upper Capitan) time, was dominated by aggradation, steepening of the shelf margin, deepening of the basin, and deposition of abundant siliciclastics on the shelf. This model differs from previous reconstructions that show uniform growth of the Capitan reef, and it contradicts the long-standing dogma of reciprocal sedimentation. This two-phase growth model adds insight into deposition of the two principle Guadalupian reservoir facies that account for nearly 50% of the Permian basin in-place oil reserves. Offlapping sheets of inner shelf carbonates (e.g., San Andres Formation, McElroy field) relate to periods of shelf progradation whereas widespread sheets of shelf clastics (e.g., Yates Formation, N. Ward Estes field) reflect periods of shelf aggradation. The model should be useful in evaluating the evolution of other shelves, particularly mixed shelves.

  8. Late Quaternary paleodune deposits in Abu Dhabi Emirate, UAF: Paleoclimatic implications

    SciTech Connect (OSTI)

    Brouwers, E.M.; Bown, T.M. (Geological Survey, Denver, CO (United States)); Hadley, D.G. (Geological Survey, Reston, VA (United States))

    1993-04-01

    Remnants of late Quaternary paleodunes are exposed near the coast of the Arabian Gulf and in large inland playas and interdunal areas in central and western Abu Dhabi Emirate over a distance of >45 km normal to the coast. Paleodunes occur south of Madinat Zayed (lat. 23[degree]35 N), which marks the northern limit of a modern dune field that grades into the mega-dune sand sea of the ar Rub al Khali, Saudi Arabia. Coastal paleodunes are composed of weakly cemented millolid foraminifers, ooids, and rounded biogenic grains, whereas inland and southward the paleodunes show a progressive increase in the proportion of eolian quartz sand. The paleodunes exhibit large-scale trough foresets in remnant exposures 0.5 to 10 m thick, indicating paleowind directions from 65[degree] to 184[degree] (dominantly southeast transport). Scattered paleoplaya remnants provide paleodune scale. Paleoplaya deposits form buttes 30--50 m high. If coeval with the Paleodunes, large-scale paleodune fields are implied (100+ m high), comparable to star dunes and sand mountains at the northwestern edge of the ar Rub al Khali. Based on U-Th isotopic analyses, the carbonate paleodune sands are >160ka and probably >250ka. The carbonate source was a shallow, nearly dry Arabian Gulf at a time when large areas were exposed during a low sea-level stand. Paleowind direction indicates that Pleistocene prevailing winds were northwesterly, the direction of the dominant (winter shamal) wind today. The geographic extend and implied magnitude of the paleodunes suggest large-scale eolian transport of carbonate sand during the Pleistocene disiccation, and admixed quartz sand identifies a youthful stage of contemporaneous evolution of the ar Rub al Khali. Wave-eroded paleodunes probably floor much of the present-day Gulf and extend beneath the modern dunes and sand mountains.

  9. Diffusion Tensor Imaging of Normal-Appearing White Matter as Biomarker for Radiation-Induced Late Delayed Cognitive Decline

    SciTech Connect (OSTI)

    Chapman, Christopher H.; Nagesh, Vijaya; Sundgren, Pia C.; Buchtel, Henry; Chenevert, Thomas L.; Junck, Larry; Lawrence, Theodore S.; Tsien, Christina I.; Cao, Yue

    2012-04-01

    Purpose: To determine whether early assessment of cerebral white matter degradation can predict late delayed cognitive decline after radiotherapy (RT). Methods and Materials: Ten patients undergoing conformal fractionated brain RT participated in a prospective diffusion tensor magnetic resonance imaging study. Magnetic resonance imaging studies were acquired before RT, at 3 and 6 weeks during RT, and 10, 30, and 78 weeks after starting RT. The diffusivity variables in the parahippocampal cingulum bundle and temporal lobe white matter were computed. A quality-of-life survey and neurocognitive function tests were administered before and after RT at the magnetic resonance imaging follow-up visits. Results: In both structures, longitudinal diffusivity ({lambda}{sub Double-Vertical-Line }) decreased and perpendicular diffusivity ({lambda}{sub Up-Tack }) increased after RT, with early changes correlating to later changes (p < .05). The radiation dose correlated with an increase in cingulum {lambda}{sub Up-Tack} at 3 weeks, and patients with >50% of cingula volume receiving >12 Gy had a greater increase in {lambda}{sub Up-Tack} at 3 and 6 weeks (p < .05). The post-RT changes in verbal recall scores correlated linearly with the late changes in cingulum {lambda}{sub Double-Vertical-Line} (30 weeks, p < .02). Using receiver operating characteristic curves, early cingulum {lambda}{sub Double-Vertical-Line} changes predicted for post-RT changes in verbal recall scores (3 and 6 weeks, p < .05). The neurocognitive test scores correlated significantly with the quality-of-life survey results. Conclusions: The correlation between early diffusivity changes in the parahippocampal cingulum and the late decline in verbal recall suggests that diffusion tensor imaging might be useful as a biomarker for predicting late delayed cognitive decline.

  10. Predictive Factors for Acute and Late Urinary Toxicity After Permanent Prostate Brachytherapy: Long-Term Outcome in 712 Consecutive Patients

    SciTech Connect (OSTI)

    Keyes, Mira Miller, Stacy; Moravan, Veronika; Pickles, Tom; McKenzie, Michael; Pai, Howard; Liu, Mitchell; Kwan, Winkle; Agranovich, Alexander; Spadinger, Ingrid; Lapointe, Vincent; Halperin, Ross; Morris, W. James

    2009-03-15

    Purpose: To describe the frequency of acute and late Radiation Therapy Oncology Group (RTOG) urinary toxicity, associated predictive factors, and resolution of International Prostate Symptom Score (IPSS) in 712 consecutive prostate brachytherapy patients. Methods and Materials: Patients underwent implantation between 1998 and 2003 (median follow-up, 57 months). The IPSS and RTOG toxicity data were prospectively collected. The patient, treatment, and implant factors were examined for an association with urinary toxicity. The time to IPSS resolution was examined using Kaplan-Meier curves, and multivariate modeling of IPSS resolution was done using Cox proportional hazards regression analysis. Logistic regression analysis was used to examine the factors associated with urinary toxicity. Results: The IPSS returned to baseline at a median of 12.6 months. On multivariate analysis, patients with a high baseline IPSS had a quicker resolution of their IPSS. Higher prostate D90 (dose covering 90% of the prostate), maximal postimplant IPSS, and urinary retention slowed the IPSS resolution time. The rate of the actuarial 5-year late urinary (>12 months) RTOG Grade 0, 1, 2, 3, and 4 was 32%, 36%, 24%, 6.2%, and 0.1%, respectively. At 7 years, the prevalence of RTOG Grade 0-1 was 92.5%. Patients with a larger prostate volume, greater number of needles, greater baseline IPSS, and use of hormonal therapy had more acute toxicity. On multivariate analysis, the significant predictors for late greater than or equal to RTOG toxicity 2 were a greater baseline IPSS, maximal postimplant IPSS, presence of acute toxicity, and higher prostate V150 (volume of the prostate covered by 150% of the dose). More recently implanted patients had less acute urinary toxicity and patients given hormonal therapy had less late urinary toxicity (all p < 0.02). Conclusion: Most urinary symptoms resolved within 12 months after prostate brachytherapy, and significant long-term urinary toxicity was very low

  11. Solar-Geophysical Data Number 557, January 1991. Part 1 (prompt reports). Data for December, November 1990 and late data

    SciTech Connect (OSTI)

    Coffey, H.E.

    1991-01-01

    ;Contents: Detailed index for 1990; Data for December 1990--Solar-terrestrial environment, IUWDS alert periods (Advance and Worldwide), Solar activity indices, Solar flares, Solar radio emission, Stanford mean solar magnetic field; Data for November 1990--Solar active regions, Sudden ionospheric disturbances, Solar radio spectral observations, Cosmic ray measurements by neutron monitor, Geomagnetic indices; Late data--Cosmic rays Huancayo September 1990, Thule July-October 1990, Geomagnetic indices, Provisional values of hourly equatorial Dst September 1989-May 1990.

  12. Solar-Geophysical Data Number 556, December 1990. Part 1 (prompt reports). Data for November, October 1990, and late data

    SciTech Connect (OSTI)

    Coffey, H.E.

    1990-12-01

    ;Contents: Detailed Index for 1990; Data for November 1990--Solar-Terrestrial Environment, IUWDS Alert Periods (Advance and Worldwide), Solar Activity Indices, Solar Flares, Solar Radio Emission, Standford Mean Solar Magnetic Field; Data for October 1990--Solar Active Regions, Sudden Ionospheric Disturbances, Solar Radio Spectral Observations, Cosmic Ray Measurements by Neutron Monitor, Geomagnetic Indices; Late Data--Cosmic Rays Huancayo August 1990, Geomagnetic Activity Indices September 1990, International Geophysical Calendar 1991 with recommended scientific programs.

  13. Prospective Study of Local Control and Late Radiation Toxicity After Intraoperative Radiation Therapy Boost for Early Breast Cancer

    SciTech Connect (OSTI)

    Chang, David W.; Marvelde, Luc te; Chua, Boon H.

    2014-01-01

    Purpose: To report the local recurrence rate and late toxicity of intraoperative radiation therapy (IORT) boost to the tumor bed using the Intrabeam System followed by external-beam whole-breast irradiation (WBI) in women with early-stage breast cancer in a prospective single-institution study. Methods and Materials: Women with breast cancer ?3 cm were recruited between February 2003 and May 2005. After breast-conserving surgery, a single dose of 5 Gy IORT boost was delivered using 50-kV x-rays to a depth of 10 mm from the applicator surface. This was followed by WBI to a total dose of 50 Gy in 25 fractions. Patients were reviewed at regular, predefined intervals. Late toxicities were recorded using the Radiation Therapy Oncology Group/European Organization for Research and Treatment of Cancer Late Radiation Morbidity Scoring systems. Results: Fifty-five patients completed both IORT boost and external-beam WBI. Median follow-up was 3.3 years (range, 1.4-4.1 years). There was no reported locoregional recurrence or death. One patient developed distant metastases. Grade 2 and 3 subcutaneous fibrosis was detected in 29 (53%) and 8 patients (15%), respectively. Conclusions: The use of IORT as a tumor bed boost using kV x-rays in breast-conserving therapy was associated with good local control but a clinically significant rate of grade 2 and 3 subcutaneous fibrosis.

  14. A late-time flattening of light curves in gamma-ray burst afterglows

    SciTech Connect (OSTI)

    Sironi, Lorenzo; Giannios, Dimitrios E-mail: dgiannio@purdue.edu

    2013-12-01

    The afterglow emission from gamma-ray bursts (GRBs) is usually interpreted as synchrotron radiation from relativistic electrons accelerated at the GRB external shock. We investigate the temporal decay of the afterglow emission at late times, when the bulk of the shock-accelerated electrons are non-relativistic (the 'deep Newtonian phase', as denoted by Huang and Cheng). We assume that the electron spectrum in the deep Newtonian phase is a power-law distribution in momentum with slope p, as dictated by the theory of Fermi acceleration in non-relativistic shocks. For a uniform circumburst medium, the deep Newtonian phase begins at t{sub DN}?3 ?{sub e,?1}{sup 5/6}t{sub ST}, where t {sub ST} marks the transition of the blast wave to the non-relativistic, spherically symmetric Sedov-Taylor (ST) solution, and ? {sub e} = 0.1 ? {sub e,1} quantifies the amount of shock energy transferred to the electrons. For typical parameters, the deep Newtonian stage starts ?0.5 to several years after the GRB. The radio flux in this phase decays as F {sub ?}?t {sup 3(p+1)/10}?t {sup (0.91.2)}, for a power-law slope 2 < p < 3. This is shallower than the scaling F {sub ?}?t {sup 3(5p7)/10}?t {sup (0.92.4)} derived by Frail et al., which only applies if the GRB shock is non-relativistic, but the electron distribution still peaks at ultra-relativistic energies (a regime that is relevant for a narrow time interval, and only if t {sub DN} ? t {sub ST}, namely, ? {sub e} ? 0.03). We discuss how the deep Newtonian phase can be reliably used for GRB calorimetry, and we comment on the good detection prospects of trans-relativistic blast waves at 0.110 GHz with the Karl G. Jansky Very Large Array and LOw-Frequency ARray.

  15. Dosimetric and Late Radiation Toxicity Comparison Between Iodine-125 Brachytherapy and Stereotactic Radiation Therapy for Juxtapapillary Choroidal Melanoma

    SciTech Connect (OSTI)

    Krema, Hatem

    2013-07-01

    Purpose: To compare the dose distributions and late radiation toxicities for {sup 125}I brachytherapy (IBT) and stereotactic radiation therapy (SRT) in the treatment of juxtapapillary choroidal melanoma. Methods: Ninety-four consecutive patients with juxtapapillary melanoma were reviewed: 30 have been treated with IBT and 64 with SRT. Iodine-125 brachytherapy cases were modeled with plaque simulator software for dosimetric analysis. The SRT dosimetric data were obtained from the Radionics XKnife RT3 software. Mean doses at predetermined intraocular points were calculated. Kaplan-Meier estimates determined the actuarial rates of late toxicities, and the logrank test compared the estimates. Results: The median follow-up was 46 months in both cohorts. The 2 cohorts were balanced with respect to pretreatment clinical and tumor characteristics. Comparisons of radiation toxicity rates between the IBT and SRT cohorts yielded actuarial rates at 50 months for cataracts of 62% and 75% (P=.1), for neovascular glaucoma 8% and 47% (P=.002), for radiation retinopathy 59% and 89% (P=.0001), and for radiation papillopathy 39% and 74% (P=.003), respectively. Dosimetric comparisons between the IBT and SRT cohorts yielded mean doses of 12.8 and 14.1 Gy (P=.56) for the lens center, 17.6 and 19.7 Gy (P=.44) for the lens posterior pole, 13.9 and 10.8 Gy (P=.30) for the ciliary body, 61.9 and 69.7 Gy (P=.03) for optic disc center, and 48.9 and 60.1 Gy (P<.0001) for retina at 5-mm distance from tumor margin, respectively. Conclusions: Late radiation-induced toxicities were greater with SRT, which is secondary to the high-dose exposure inherent to the technique as compared with IBT. When technically feasible, IBT is preferred to treat juxtapapillary choroidal melanoma.

  16. High-resolution dynamically downscaled projections of precipitation in the mid and late 21st century over North America

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    none,

    2015-07-29

    This study performs high-spatial-resolution (12 km) Weather Research and Forecasting (WRF) simulations over a very large domain (7200 km × 6180 km, covering much of North America) to explore changes in mean and extreme precipitation in the mid and late 21st century under Representative Concentration Pathways 4.5 (RCP 4.5) and 8.5 (RCP 8.5). We evaluate WRF model performance for a historical simulation and future projections, applying the Community Climate System Model version 4 (CCSM4) as initial and boundary conditions with and without a bias correction. WRF simulations using boundary and initial conditions from both versions of CCSM4 show smaller biasesmore » versus evaluation data sets than does CCSM4 over western North America. WRF simulations also improve spatial details of precipitation over much of North America. However, driving the WRF with the bias-corrected CCSM4 does not always reduce the bias. WRF-projected changes in precipitation include decreasing intensity over the southwestern United States, increasing intensity over the eastern United States and most of Canada, and an increase in the number of days with heavy precipitation over much of North America. Projected precipitation changes are more evident in the late 21st century than the mid 21st century, and they are more evident under RCP 8.5 than under RCP 4.5 in the late 21st century. Uncertainties in the projected changes in precipitation due to different warming scenarios are non-negligible. Differences in summer precipitation changes between WRF and CCSM4 are significant over most of the United States.« less

  17. High-resolution dynamically downscaled projections of precipitation in the mid and late 21st century over North America

    SciTech Connect (OSTI)

    none,

    2015-07-29

    This study performs high-spatial-resolution (12 km) Weather Research and Forecasting (WRF) simulations over a very large domain (7200 km × 6180 km, covering much of North America) to explore changes in mean and extreme precipitation in the mid and late 21st century under Representative Concentration Pathways 4.5 (RCP 4.5) and 8.5 (RCP 8.5). We evaluate WRF model performance for a historical simulation and future projections, applying the Community Climate System Model version 4 (CCSM4) as initial and boundary conditions with and without a bias correction. WRF simulations using boundary and initial conditions from both versions of CCSM4 show smaller biases versus evaluation data sets than does CCSM4 over western North America. WRF simulations also improve spatial details of precipitation over much of North America. However, driving the WRF with the bias-corrected CCSM4 does not always reduce the bias. WRF-projected changes in precipitation include decreasing intensity over the southwestern United States, increasing intensity over the eastern United States and most of Canada, and an increase in the number of days with heavy precipitation over much of North America. Projected precipitation changes are more evident in the late 21st century than the mid 21st century, and they are more evident under RCP 8.5 than under RCP 4.5 in the late 21st century. Uncertainties in the projected changes in precipitation due to different warming scenarios are non-negligible. Differences in summer precipitation changes between WRF and CCSM4 are significant over most of the United States.

  18. Shelf margin bioherms and associated facies in the Lower Permian Hueco Group (Late Wolfcampian), Hueco Mountains, West Texas

    SciTech Connect (OSTI)

    Wahlman, G.P.; Tasker, D.R.; St. John, J.W.; Werle, K.J. )

    1992-01-01

    Late Wolfcampian phylloid algal/Tubiphytes biohermal complexes are exposed in three erosional oilers lying about 3 miles west of and parallel to the main Hueco Mountains in far West Texas. The biohermal complexes are located paleogeographically along the shelf margin between the Diablo Platform and Orogrande Basin. Based on fusulinids the shelf margin buildups correlate with well-bedded shelf carbonates of the type Hueco Group in the main Hueco Mountains. The phylloid algal/Tubiphytes shelf margin bioherms contain an upward shallowing facies succession, which, in ascending order, consists of: (1) phylloid algal wackestone-bafflestone, (2) phylloid algal-fusulinid bafflestone-packstone, and (3) Tubiphytes boundstone and Tubiphytes-fusulinid-phylloid algal packstone-grainstone. The crest of the southernmost outlier has a different type of bioherm that consists of nodular boundstones composed of calcisponges, encrusting bryozoans and laminar red algae. The shelf margin complexes prograded over slope facies of dark-gray cherty limestones, which generally lack skeletal fossils, but contain common ichnofossils in upper slope beds. Overlapping tongues and channels of lithoclastic-skeletal packstones and grainstones extend seaward from the phylloid algal/Tubiphytes bioherms into the dark-gray slope facies. Proximal backreef facies consist of mainly skeletal-peloidal packstones and wackestones. The Hueco Mountains outlier exposures are important because: (1) they confirm a Late Wolfcampian shelf margin with distinct topographic relief in the southern Orogrande Basin, and (2) they provide an easily accessible field laboratory where Wolfcampian shelf-to-basin facies relationships and shelf margin bioherms can be studied. Wolfcampian bioherms represent a significant stage in the evolutionary history of Late Paleozoic reef communities and form important petroleum reservoirs in the adjacent Permian Basin.

  19. Nuclear substructure reorganization during late stageerythropoiesis is selective and does not involve caspase cleavage ofmajor nuclear substructural proteins

    SciTech Connect (OSTI)

    Krauss, Sharon Wald; Lo, Annie J.; Short, Sarah A.; Koury, MarkJ.; Mohandas, Narla; Chasis, Joel Anne

    2005-04-06

    Enucleation, a rare feature of mammalian differentiation, occurs in three cell types: erythroblasts, lens epithelium and keratinocytes. Previous investigations suggest that caspase activation functions in lens epithelial and keratinocyte enucleation, as well as in early erythropoiesis encompassing BFU-E differentiation to proerythroblast. To determine whether caspase activation contributes to later erythropoiesis and whether nuclear substructures other than chromatin reorganize, we analyzed distributions of nuclear subcompartment proteins and assayed for caspase-induced cleavage of subcompartmental target proteins in mouse erythroblasts. We found that patterns of lamin B in the filamentous network interacting with both the nuclear envelope and DNA, nuclear matrix protein NuMA, and splicing factors Sm and SC35 persisted during nuclear condensation, consistent with effective transcription of genes expressed late in differentiation. Thus nuclear reorganization prior to enucleation is selective, allowing maintenance of critical transcriptional processes independent of extensive chromosomal reorganization. Consistent with these data, we found no evidence for caspase-induced cleavage of major nuclear subcompartment proteins during late erythropoiesis, in contrast to what has been observed in early erythropoiesis and in lens epithelial and keratinocyte differentiation. These findings imply that nuclear condensation and extrusion during terminal erythroid differentiation involve novel mechanisms that do not entail major activation of apoptotic machinery.

  20. A closer look at the fluctuations in the brightness of SN 2009IP during its late 2012 eruption

    SciTech Connect (OSTI)

    Martin, J. C. [Barber Observatory, University of Illinois Springfield, Springfield, IL 62704 (United States); Hambsch, F.-J. [Remote Observatory, Atacama Desert, Chile Vereniging Voor Sterrenkunde (VVS), Oude Bleken 12, B-2400 Mol (Belgium); Margutti, R.; Soderberg, A. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02318 (United States); Tan, T. G. [Perth Exoplanet Survey Telescope, Perth (Australia); Curtis, I., E-mail: jmart5@uis.edu [Adelaide (Australia)

    2015-01-01

    The supernova (SN) impostor SN 2009ip has re-brightened several times since its initial discovery in 2009 August. During its last outburst in late 2012 September, it reached a peak brightness of m{sub v} ?13.5 (M{sub v} brighter than ?18), causing some to speculate that it had undergone a terminal core-collapse SN. Relatively high-cadence multi-wavelength photometry of the post-peak decline revealed bumps in brightness infrequently observed in other SNe IIn. These bumps occurred synchronously in all ultraviolet (UV) and optical bands with amplitudes of 0.10.4 mag at intervals of 1030 days. Episodic continuum brightening and dimming in the UV and optical with these characteristics is not easily explained within the context of models that have been proposed for the late September 2012 outburst of SN 2009ip. We also present evidence that the post-peak fluctuations in brightness occur at regular intervals and raise more questions about their origin.

  1. A reassessment of the referral of Sea Turtle skulls to Osteopygis(Late Cretaceous, New Jersey, USA)

    SciTech Connect (OSTI)

    Parham, James F.

    2005-01-01

    Specimens referred to Osteopygis (Late Cretaceous-Paleocene,North America) represent a chimera, a polyphyletic mixture of taxa. Theholotype of Osteopygis (AMNH 1485) and more complete referred postcranialspecimens resemble non-marine stem cryptodires ("macrobaenids"). Becausethe skull material historically referredto Osteopygis sharessynapomorphies with cheloniid sea turtles, all current workers acceptOsteopygis as a stem-cheloniid sea turtle. Multiple lines of evidencecombine to support the hypothesis that sea turtle cranial material is notattributable to Osteopygis. These lines of evidence include: phylogenetichypotheses of character evolution, the tenuous historical attribution ofspecimens, and the taphonomy of the Hornerstown Formation. Thename-bearing Osteopygis material and referred postcrania are bestconsidered Eucryptodira incertae sedis (cf. "Macrobaenidae"). The cranialspecimens formerly assigned to the Osteopyginae now are restricted to theclade Euclastes and those referred to Osteopygis emarginatus are herereferred to Euclastes wielandi (comb. nov.). The 'decapitation' ofOsteopygis reconciles morphological trends within stemcheloniids.

  2. SU-E-T-381: Radio-Dynamic Therapy (RDT) for the Treatment of Late-Stage Cancers

    SciTech Connect (OSTI)

    Ma, C; Chen, L; Price, R [Fox Chase Cancer Center, Philadelphia, PA (United States); Zhang, Q [Wu Xi Yi Ren Tumor Hosiptal, Wuxi, Jiangsu (China); Zeng, J; Xu, K; Sun, Q [Wuxi Yiren Cancer Hospital, Wuxi, Jiangsu (China)

    2014-06-01

    Purpose: Photo-dynamic therapy (PDT) is an effective treatment modality because of the preferential absorption of photosensitizing agent in tumor cells than in surrounding normal tissues. A limitation of PDT for cancer therapy is the finite penetration of laser light to activate the targeting agent in deep-seated tumors. Radio-dynamic therapy (RDT) is designed to overcome this problem by the combination of high-energy (up to 45MV) photon beams and photo/radio-sensitizers. This work investigates the feasibility of PDT for late-stage cancer patients who are no longer respond to conventional therapies available. Methods: The high-energy photon beams are generated using a LA45 RaceTrack Microtron (Top Grade Medical, Beijing, China). The targeting agent investigated is 5- aminolevulinic acid (5-ALA). Both in vitro cell lines and in vivo animal models have been used to investigate the mechanisms of RDT and its therapeutic effects and normal tissue toxicities. Oral 5-ALA (30-60 mg/kg) was administered 4-6 hours before the radiation treatment and the total radiation dose varied between 0.1-4.0Gy in 1-4 fractions. Clinical trials are initiated in China for late-stage cancer patients targeting both primary tumors utilizing localized therapies such as 3DCRT/IMRT and metastases using TBI. Results: There is clear correlation between the cell death and the 5-ALA concentration/radiation dose. The therapeutic effect of RDT is demonstrated using an animal model where the volume of parotid tumors for the RT only group continued to grow after 3Gy irradiation while the RDT group showed a complete response with the same radiation dose. The preliminary clinical results showed encouraging clinical outcome. Conclusion: RDT is a novel treatment technique that may be developed into an effective cancer treatment modality. Further studies on the mechanisms of RDT and its potential clinical applications are warranted.

  3. Sedimentology and diagenesis of windward-facing fore-reef calcarenites, Late Pleistocene of Barbados, West Indies

    SciTech Connect (OSTI)

    Humphrey, J.D.; Kimbell, T.N.

    1989-03-01

    Late Pleistocene reef terraces in southeastern Barbardos developed extensive fore-reef sand facies during deposition in response to high-energy windward-facing conditions. Sedimentology and diagenesis of these deposits illustrate significant contrasts with previous studies from the leeward west coast. These calcarenites are dominantly skeletal packstones with less common grainstones and wackestones present. The fore-reef sand facies occurs within progradational reef sequences, being conformably overlain by deep-water head coral facies. Medium-bedded, laterally continuous sand sheets retain original depositional slopes, dipping seaward at 10/degrees/-15/degrees/. These fore-reef deposits, in places, are over 30 m thick (average 20 m) and developed rapidly during late Pleistocene glacio-eustatic sea level highstands. Sedimentation rate ranges from 2 to 5 m/1000 years. Areal extent of fore-reef calcarenites in southeastern Barbados is estimated to be 8-10 km/sup 2/. Lithologically, the packstones are composed of an abundance of coralline red algae and the benthic foraminifer Amphistegina sp. Other volumetrically significant allochems include echinoids, mollusks, rhodoliths, peloids, and micritized grains. Micrite in the wackestone and packstone lithologies is likely derived from intense physical/mechanical abrasion of shoal-water reef facies. Diagenesis of these lithologies reflects a complex interplay of meteoric, mixing zone, and marine environments as a result of glacio-eustasy. Differences in diagenetic character are derived from differences in terrace ages, terrace geometry, a paleotopographic control on meteoric ground-water distribution, and high-energy coastal conditions. Diagenetic fabrics include equant, blocky meteoric phreatic calcite; limpid dolomite of mixing zone origin: and peloidal and isopachous fibrous cements from marine precipitation.

  4. Sequence stratigraphy of carbonate buildups developed in an active tectonic/volcanic setting: Triassic (Late Ladinian and Carnian) of the Dolomites, northern Italy

    SciTech Connect (OSTI)

    Yose, L.A. ); Littmann, P. )

    1991-03-01

    Late Ladinian and Carnian deposits of the Dolomites record the evolution of carbonate buildups developed during the waning phases of a major period of volcanism and strike-slip tectonics. Each separate buildup provides an independent record of eustasy, tectonism, and competing carbonate and volcaniclastic sedimentation. Palynomorphs, calibrated with ammonites, are used to correlate between buildups and provide a means for distinguishing local variations in buildup histories from regional, synchronous trends in sedimentation which may record third-order eustasy. Although individual buildup histories vary dramatically, two depositional sequences may be recorded at a regional scale: one of late Ladinian age (early to late Longobardian) and another of late Ladinian to middle Carnian age (late Longobardian to Cordevolian). A relative sea-level fall in the late Ladinian resulted in an increased supply of volcaniclastics that onlap the flanks of many buildups and/or downslope shifts in carbonate production. Buildups of the second sequence developed in response to a relative sea-level rise and are similar in diversity to those of the first sequence. Extensive buildup progradation and accretion during this phase, concomitant with mixed-carbonate/volcaniclastic basin filling and diminished tectonic activity, result in a regional suturing of the complex paleogeography developed during the middle Ladinian. Local paleogeography, determined by the distribution of earlier platforms in addition to tectonic and volcanogenic processes, is interpreted as the primary control over buildup geometries and the variability of buildups within sequences. However, the regional extent and synchroneity of the sequences described above many record third-order eustasy.

  5. Total synthesis of gracilioether F. Development and application of Lewis acid promoted ketenealkene [2+2] cycloadditions and late-stage CH oxidation

    SciTech Connect (OSTI)

    Rasik, Christopher M.; Brown, M. Kevin

    2014-12-22

    The first synthesis of gracilioether F, a polyketide natural product with an unusual tricyclic core and five contiguous stereocenters, is described. Key steps of the synthesis include a Lewis acid promoted ketenealkene [2+2] cycloaddition and a late-stage carboxylic acid directed C(sp)H oxidation. The synthesis requires only eight steps from norbornadiene.

  6. Constraints on the binary properties of mid- to late T dwarfs from Hubble space telescope WFC3 observations

    SciTech Connect (OSTI)

    Aberasturi, M.; Solano, E.; Burgasser, A. J.; Mora, A.; Martín, E. L.; Reid, I. N.; Looper, D.

    2014-12-01

    We used Hubble Space Telescope/Wide Field Camera 3 (WFC3) observations of a sample of 26 nearby (≤20 pc) mid- to late T dwarfs to search for cooler companions and measure the multiplicity statistics of brown dwarfs (BDs). Tightly separated companions were searched for using a double point-spread-function-fitting algorithm. We also compared our detection limits based on simulations to other prior T5+ BD binary programs. No new wide or tight companions were identified, which is consistent with the number of known T5+ binary systems and the resolution limits of WFC3. We use our results to add new constraints to the binary fraction (BF) of T-type BDs. Modeling selection effects and adopting previously derived separation and mass ratio distributions, we find an upper limit total BF of <16% and <25% assuming power law and flat mass ratio distributions, respectively, which are consistent with previous results. We also characterize a handful of targets around the L/T transition.

  7. Status Update on the NCRP Scientific Committee SC 5-1 Report: Decision Making for Late-Phase Recovery from Nuclear or Radiological Incidents - 13450

    SciTech Connect (OSTI)

    Chen, S.Y.

    2013-07-01

    In August 2008, the U.S. Department of Homeland Security (DHS) issued its final Protective Action Guide (PAG) for radiological dispersal device (RDD) and improvised nuclear device (IND) incidents. This document specifies protective actions for public health during the early and intermediate phases and cleanup guidance for the late phase of RDD or IND incidents, and it discusses approaches to implementing the necessary actions. However, while the PAG provides specific guidance for the early and intermediate phases, it prescribes no equivalent guidance for the late-phase cleanup actions. Instead, the PAG offers a general description of a complex process using a site-specific optimization approach. This approach does not predetermine cleanup levels but approaches the problem from the factors that would bear on the final agreed-on cleanup levels. Based on this approach, the decision-making process involves multifaceted considerations including public health, the environment, and the economy, as well as socio-political factors. In an effort to fully define the process and approach to be used in optimizing late-phase recovery and site restoration following an RDD or IND incident, DHS has tasked the NCRP with preparing a comprehensive report addressing all aspects of the optimization process. Preparation of the NCRP report is a three-year (2010-2013) project assigned to a scientific committee, the Scientific Committee (SC) 5-1; the report was initially titled, Approach to Optimizing Decision Making for Late- Phase Recovery from Nuclear or Radiological Terrorism Incidents. Members of SC 5-1 represent a broad range of expertise, including homeland security, health physics, risk and decision analysis, economics, environmental remediation and radioactive waste management, and communication. In the wake of the Fukushima nuclear accident of 2011, and guided by a recent process led by the White House through a Principal Level Exercise (PLE), the optimization approach has since

  8. A detailed 2,000-year late holocene pollen record from lower Pahranagat Lake, Southern Nevada, USA

    SciTech Connect (OSTI)

    Hemphill, M.L.; Wigand, P.E.

    1995-09-01

    Preliminary analysis of 128 pollen samples and seven radiocarbon dates from a 5-meter long, 10-cm diameter sediment core retrieved from Lower Pahranagat Lake (elevation - 975 in), Lincoln County, Nevada, gives us a rare, continuous, record of vegetation change at an interval of every 14 years over the last 2,000 years. During this period increasing Pinus (pine) pollen values with respect to Juniperus Ouniper pollen values reflect the increasing dominance of pinyon in southern Nevada woodlands during the last 2,000 years. Today Pinus pollen values indicate that pinyon pine is more frequent in the southern Great Basin since the end of the Neoglacial 2,000 years ago. During the same time frame, a general decrease in Poaceae (grass) pollen values with respect to Artemisia (sagebrush) pollen values reflect the general trend of increasing dominance of steppe and desert scrub species with respect to grasses. Variations in these two species reflect not only the generally more xeric nature of climate during the last 2,000 years, but also periods of summer shifted rainfall - 1,500 years ago that encouraged both a period of grass and pinyon expansion. The ratio of aquatic to littoral pollen types indicates generally deeper water conditions 2 to 1 ka and more variable, but predominately more marshy, conditions at the site during most of the last 1 ka. Investigation of ostracodes from the same record being conducted by Dr. R. Forester at the USGS corroborate the pollen record by evidencing shifts between open and closed hydrologic systems including lake, marsh and even stream habitats. Analysis of an additional 10 meters of core recovered in the summer of 1994 with a basal date of 5.6 ka promises to provide the best record of middle through late Holocene vegetation and climate history for southern Nevada.

  9. Association Between Disruption of Fibrin Sheaths Using Percutaneous Transluminal Angioplasty Balloons and Late Onset of Central Venous Stenosis

    SciTech Connect (OSTI)

    Ni, Nina Mojibian, Hamid; Pollak, Jeffrey; Tal, Michael

    2011-02-15

    To compare the rates of central venous stenosis in patients undergoing hemodialysis who underwent disruption of fibrin sheath with percutaneous transluminal angioplasty balloons and those who underwent over-the-wire catheter exchange. This study is a retrospective review of 209 percutaneous transluminal angioplasty balloon disruption and 1304 over-the-wire catheter exchange procedures performed in 753 patients. Approval from the Human Investigations Committee was obtained for this study. Up to 10-year follow-up was performed. A {chi}{sup 2} test was used to compare the rates of central venous stenosis after balloon disruption versus catheter exchange. A t-test was used to compare time to central venous stenosis development. Of the 753 patients in the study, 127 patients underwent balloon disruption of fibrin sheath and 626 had catheter exchange. Within the balloon disruption group, 18 (14.2%) of 127 patients subsequently developed central venous stenosis, compared with 44 (7.0%) of 626 in the catheter exchange group (P < 0.01, {chi}{sup 2} test). Time to central venous stenosis development was approximately 3 years in both groups and not significantly different (1371 and 1010 days, P = 0.20). A total of 25.2% of patients in the balloon disruption group had four or more subsequent catheter exchanges, versus 12.6% in the catheter exchange group (P < 0.01, {chi}{sup 2} test). In conclusions, there is a possible association between percutaneous transluminal angioplasty balloon disruption of fibrin sheath and late-onset central venous stenosis. Because venography was not routinely performed in catheter exchange patients, future randomized studies are necessary to confirm these findings.

  10. Detailed Analysis of a Late-Phase Core-Melt Progression for the Evaluation of In-vessel Corium Retention

    SciTech Connect (OSTI)

    J. L. Rempe; R. J. Park; S. B. Kim; K. Y. Suh; F. B.Cheung

    2006-12-01

    Detailed analyses of a late-phase melt progression in the advanced power reactor (APR)1400 were completed to identify the melt and the thermal-hydraulic states of the in-vessel materials in the reactor vessel lower plenum at the time of reactor vessel failure to evaluate the candidate strategies for an in-vessel corium retention (IVR). Initiating events considered included high-pressure transients of a total loss of feed water (LOFW) and a station blackout (SBO) and low-pressure transients of a 0.0009-m2 small, 0.0093-m2 medium, and 0.0465-m2 large-break loss-of-coolant accident (LOCA) without safety injection. Best-estimate simulations for these low-probability events with conservative accident progression assumptions that lead to reactor vessel failure were performed by using the SCDAP/RELAP5/MOD3.3 computer code. The SCDAP/RELAP5/MOD3.3 results have shown that the pressurizer surge line failed before the reactor vessel failure, which results in a rapid decrease of the in-vessel pressure and a delay of the reactor vessel failure time of ~40 min in the high-pressure sequences of the total LOFW and the SBO transients. In all the sequences, ~80 to 90% of the core material was melted and relocated to the lower plenum of the reactor vessel at the time of reactor vessel failure. The maximum value of the volumetric heat source in the corium pool was estimated as 1.9 to 3.7 MW/m3. The corium temperature was ~2800 to 3400 K at the time of reactor vessel failure. The highest volumetric heat source sequence is predicted for the 0.0465-m2 large-break LOCA without safety injection in the APR1400, because this sequence leads to an early reactor vessel failure.

  11. FIRE SPECTROSCOPY OF FIVE LATE-TYPE T DWARFS DISCOVERED WITH THE WIDE-FIELD INFRARED SURVEY EXPLORER

    SciTech Connect (OSTI)

    Burgasser, Adam J.; Cushing, Michael C.; Mainzer, A.; Bauer, James M.; Kirkpatrick, J. Davy; Gelino, Christopher R.; Griffith, Roger L.; Marsh, Kenneth A.; Looper, Dagny L.; Tinney, Christopher; Simcoe, Robert A.; Bochanski, John J.; Skrutskie, Michael F.; Thompson, Maggie A.; Wright, Edward L.

    2011-07-10

    We present the discovery of five late-type T dwarfs identified with the Wide-field Infrared Survey Explorer (WISE). Low-resolution near-infrared spectroscopy obtained with the Magellan Folded-port InfraRed Echellette reveal strong H{sub 2}O and CH{sub 4} absorption in all five sources, and spectral indices and comparison to spectral templates indicate classifications ranging from T5.5 to T8.5:. The spectrum of the latest-type source, WISE J1812+2721, is an excellent match to that of the T8.5 companion brown dwarf Wolf 940B. WISE-based spectrophotometric distance estimates place these T dwarfs at 12-13 pc from the Sun, assuming they are single. Preliminary fits of the spectral data to the atmosphere models of Saumon and Marley indicate effective temperatures ranging from 600 K to 930 K, both cloudy and cloud-free atmospheres, and a broad range of ages and masses. In particular, two sources show evidence of both low surface gravity and cloudy atmospheres, tentatively supporting a trend noted in other young brown dwarfs and exoplanets. In contrast, the high proper motion T dwarf WISE J2018-7423 exhibits a suppressed K-band peak and blue spectrophotometric J - K colors indicative of an old, massive brown dwarf; however, it lacks the broadened Y-band peak seen in metal-poor counterparts. These results illustrate the broad diversity of low-temperature brown dwarfs that will be uncovered with WISE.

  12. Regional basinal sandstone depositional patterns during the Guadalupian (Late Permian), Delaware basin, west Texas-New Mexico

    SciTech Connect (OSTI)

    Geisen, J.H.; Scholle, P.A. )

    1990-05-01

    Examination of well logs from more than 300 Delaware basin wells penetrating the Bell Canyon and Brushy Canyon formations has allowed definition of regional depositional patterns during the Late Permian (Guadalupian). Characteristic gamma-ray hot-kicks mark thin but widespread calcareous shales or limestones representing starved basin sedimentation during sea level highstands. Correlation of such markers along three strike and ten dip lines permitted isopaching of intervening lowstand clastic wedges. The low-stand wedges typically thin significantly from basin margin to basin center and are marked by a prominent linearity oriented perpendicular to the margin. These lineations probably represent channelized turbidite and grain-flow deposits. Most intervals show dozens of such lineations indicating multiple input points for terrigenous detritus rather than just a few major point sources of debris. The resulting deposits appear to be more apron-like than fan-like and coalesce into broad, sheetlike deposits toward the basin center. Isopach thicks vary in position through time, but terrigenous sediment transport is predominantly from northerly directions throughout the analyzed interval. Thus, the filling of the Midland basin at the close of Cherry Canyon deposition did not result in a major new source of terrigenous debris from the east (Central Basin platform). The well-sorted nature of the basinal sands, their widely distributed input points, apron-like geometry, and other factors argue for migration of eolian dunes to the shelf margin during sea level lowstands. Transport of these well-sorted, unconsolidated sands into the basin was not however, mainly by direct eolian processes as has been proposed recently, but must have involved submarine current mechanisms.

  13. A Novel Method for Predicting Late Genitourinary Toxicity After Prostate Radiation Therapy and the Need for Age-Based Risk-Adapted Dose Constraints

    SciTech Connect (OSTI)

    Ahmed, Awad A.; Egleston, Brian; Alcantara, Pino; Li, Linna; Pollack, Alan; Horwitz, Eric M.; Buyyounouski, Mark K.

    2013-07-15

    Background: There are no well-established normal tissue sparing dosevolume histogram (DVH) criteria that limit the risk of urinary toxicity from prostate radiation therapy (RT). The aim of this study was to determine which criteria predict late toxicity among various DVH parameters when contouring the entire solid bladder and its contents versus the bladder wall. The area under the histogram curve (AUHC) was also analyzed. Methods and Materials: From 1993 to 2000, 503 men with prostate cancer received 3-dimensional conformal RT (median follow-up time, 71 months). The whole bladder and the bladder wall were contoured in all patients. The primary endpoint was grade ?2 genitourinary (GU) toxicity occurring ?3 months after completion of RT. Cox regressions of time to grade ?2 toxicity were estimated separately for the entire bladder and bladder wall. Concordance probability estimates (CPE) assessed model discriminative ability. Before training the models, an external random test group of 100 men was set aside for testing. Separate analyses were performed based on the mean age (? 68 vs >68 years). Results: Age, pretreatment urinary symptoms, mean dose (entire bladder and bladder wall), and AUHC (entire bladder and bladder wall) were significant (P<.05) in multivariable analysis. Overall, bladder wall CPE values were higher than solid bladder values. The AUHC for bladder wall provided the greatest discrimination for late bladder toxicity when compared with alternative DVH points, with CPE values of 0.68 for age ?68 years and 0.81 for age >68 years. Conclusion: The AUHC method based on bladder wall volumes was superior for predicting late GU toxicity. Age >68 years was associated with late grade ?2 GU toxicity, which suggests that risk-adapted dose constraints based on age should be explored.

  14. Sedimentary evolution of the upper Cretaceous and late Oligocene sequences, and its relation to oil production, North Monagas area, Eastern Venezuela

    SciTech Connect (OSTI)

    Sambrano, J.; Rojas, B.; Rendon, J.; Chigne, R.; Maguregui, J.

    1996-08-01

    The most important oil reservoirs of the Eastern Venezuela Basin are located in the North Monagas Area. These reservoirs are contained within a 3500 ft Cretaceous to Late Oligocene sedimentary section. Daily production is rated at about 350 MBO and 1000 MMCFG. At this moment, these reservoirs are undergoing special studies, in order to establish enhanced recovery projects, for which heterogeneity definition is very important. The database consisted of log analyses of 136 wells, sedimentological and biostratigraphic interpretation of 10,200 ft of cores, and biostratigraphic interpretation of ditch samples from 13 wells. Sedimentary models, based on facies analyses and deltaic conceptual models of 31 separate genetic units were defined. The models allowed for the interpretation of paleoenvironments, sedimentary facies architecture, direction of sedimentation and depocenters. The preferred sediment orientation was determined to be West-East. In the Santa Barbara and Pirital reservoirs the Late Oligocene sediments are composed of fluvial deposits, and the Cretaceous sediments of estuarine deposits. In the Carito-Mulata reservoirs, the Late Oligocene sediments are composed of fluvial to marine deposits, and the Upper Cretaceous sediments of estuarine deposits. Possible preferred transmissibility pathways for fluid injection were described, providing a great support for the enhanced recovery phases of these reservoirs.

  15. Age and Comorbid Illness Are Associated With Late Rectal Toxicity Following Dose-Escalated Radiation Therapy for Prostate Cancer

    SciTech Connect (OSTI)

    Hamstra, Daniel A.; Stenmark, Matt H.; Ritter, Tim; Litzenberg, Dale; Jackson, William; Johnson, Skyler; Albrecht-Unger, Liesel; Donaghy, Alex; Phelps, Laura; Blas, Kevin; Halverson, Schuyler; Marsh, Robin; Olson, Karin; Feng, Felix Y.

    2013-04-01

    Purpose: To assess the impacts of patient age and comorbid illness on rectal toxicity following external beam radiation therapy (EBRT) for prostate cancer and to assess the Qualitative Analysis of Normal Tissue Effects in the Clinic (QUANTEC) normal tissue complication probability (NTCP) model in this context. Methods and Materials: Rectal toxicity was analyzed in 718 men previously treated for prostate cancer with EBRT (≥75 Gy). Comorbid illness was scored using the Charlson Comorbidity Index (CCMI), and the NTCP was evaluated with the QUANTEC model. The influence of clinical and treatment-related parameters on rectal toxicity was assessed by Kaplan-Meier and Cox proportional hazards models. Results: The cumulative incidence of rectal toxicity grade ≥2 was 9.5% and 11.6% at 3 and 5 years and 3.3% and 3.9% at 3 and 5 years for grade ≥3 toxicity, respectively. Each year of age predicted an increasing relative risk of grade ≥2 (P<.03; hazard ratio [HR], 1.04 [95% confidence interval (CI), 1.01-1.06]) and ≥3 rectal toxicity (P<.0001; HR, 1.14 [95% CI,1.07-1.22]). Increasing CCMI predicted rectal toxicity where a history of either myocardial infarction (MI) (P<.0001; HR, 5.1 [95% CI, 1.9-13.7]) or congestive heart failure (CHF) (P<.0006; HR, 5.4 [95% CI, 0.6-47.5]) predicted grade ≥3 rectal toxicity, with lesser correlation with grade ≥2 toxicity (P<.02 for MI, and P<.09 for CHF). An age comorbidity model to predict rectal toxicity was developed and confirmed in a validation cohort. The use of anticoagulants increased toxicity independent of age and comorbidity. NTCP was prognostic for grade ≥3 (P=.015) but not grade ≥2 (P=.49) toxicity. On multivariate analysis, age, MI, CHF, and an NTCP >20% all correlated with late rectal toxicity. Conclusions: Patient age and a history of MI or CHF significantly impact rectal toxicity following EBRT for the treatment of prostate cancer, even after controlling for NTCP.

  16. Characterization of the Products of the Heme Detoxification Pathway in Malarial Late Trophozoites by X-ray Diffraction

    SciTech Connect (OSTI)

    Bohle,D.; Dinnebier, R.; Madsen, S.; Stephens, P.

    2007-01-01

    Heme is a potent multifunction regulator whose biochemical levels and distribution are precisely controlled on both intra- and extracellular levels. Efficient regulation of heme is particularly critical for intra-erythrocytic parasites such as plasmodia which process large quantities of heme in the post-invasion digestion of the erythrocyte's hemoglobin. Plasmodia, which lack heme oxygenases, detoxify heme by sequestering it into an insoluble heme aggregate termed malarial pigment or hemozoin. The quinoline-based family of antimalarials interfere with this process by an as yet unknown mechanism that has recently come under intense scrutiny as part of the effort to combat the spread of chloroquine-resistant strains of Plasmodium. A variety of spectroscopic and bioanalytical techniques indicate that hemozoin is similar to the synthetic aggregated heme phase {beta}-hematin, which is thought to form strands of hemes linked by propionate oxygen-iron bonds as well as interstrand propionate hydrogen bonds. Characterization of the carboxylate stretching bands for the propionic acid side chains by IR and Raman spectroscopy provides the best evidence for the presence of iron-oxygen bonds to the propionate side chains. Unfortunately, crystallographic characterization of these heme aggregates has been hampered by the phase heterogeneity of many synthetic preparations as well as by the small size of the synthetic and natural crystallites isolated from either trophozoites and infected hosts. High resolution powder diffraction has been used extensively for the solution of many structural problems, and it can solve problems posed by diffraction from microcrystalline phases. In this communication we describe the characterization of {beta}-hematin derived from both synthetic and natural sources and provide new unambiguous evidence that the heme aggregate present in late stage trophozoites is {beta}-hematin. In a process inhibited by the quinoline antimalarial drugs, Plasmodia

  17. Late Patient-Reported Toxicity After Preoperative Radiotherapy or Chemoradiotherapy in Nonresectable Rectal Cancer: Results From a Randomized Phase III Study

    SciTech Connect (OSTI)

    Braendengen, Morten, E-mail: mortbrae@medisin.uio.no [Oslo University Hospital, Ulleval, Cancer Centre, Oslo (Norway); Department of Oncology and Pathology, Karolinska Institutet, Stockholm (Sweden); Tveit, Kjell Magne [Oslo University Hospital, Ulleval, Cancer Centre, Oslo (Norway); Faculty of Medicine, University of Oslo, Oslo (Norway); Bruheim, Kjersti [Oslo University Hospital, Ulleval, Cancer Centre, Oslo (Norway); Cvancarova, Milada [Department of Clinical Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo (Norway); Berglund, Ake [Department of Oncology, Radiology and Clinical Immunology, University of Uppsala, Uppsala (Sweden); Glimelius, Bengt [Department of Oncology and Pathology, Karolinska Institutet, Stockholm (Sweden); Department of Oncology, Radiology and Clinical Immunology, University of Uppsala, Uppsala (Sweden)

    2011-11-15

    Purpose: Preoperative chemoradiotherapy (CRT) is superior to radiotherapy (RT) in locally advanced rectal cancer, but the survival gain is limited. Late toxicity is, therefore, important. The aim was to compare late bowel, urinary, and sexual functions after CRT or RT. Methods and Materials: Patients (N = 207) with nonresectable rectal cancer were randomized to preoperative CRT or RT (2 Gy Multiplication-Sign 25 {+-} 5-fluorouracil/leucovorin). Extended surgery was often required. Self-reported late toxicity was scored according to the LENT SOMA criteria in a structured telephone interview and with questionnaires European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire (QLQ-C30), International Index of Erectile Function (IIEF), and sexual function -vaginal changes questionnaire (SVQ). Results: Of the 105 patients alive in Norway and Sweden after 4 to 12 years of follow-up, 78 (74%) responded. More patients in the CRT group had received a stoma (73% vs. 52%, p = 0.09). Most patients without a stoma (7 of 12 in CRT group and 9 of 16 in RT group) had incontinence for liquid stools or gas. No stoma and good anal function were seen in 5 patients (11%) in the CRT group and in 11 (30%) in the RT group (p = 0.046). Of 44 patients in the CRT group, 12 (28%) had had bowel obstruction compared with 5 of 33 (15%) in the RT group (p = 0.27). One-quarter of the patients reported urinary incontinence. The majority of men had severe erectile dysfunction. Few women reported sexual activity during the previous month. However, the majority did not have concerns about their sex life. Conclusions: Fecal incontinence and erectile dysfunction are frequent after combined treatment for locally advanced rectal cancer. There was a clear tendency for the problems to be more common after CRT than after RT.

  18. Early-to-late-diagenetic dolomitization of platform carbonates: Lower Ordovician Ellenburger Group, Permian basin, west Texas and southeastern New Mexico

    SciTech Connect (OSTI)

    Amthor, J.E. ); Friedman, G.M. Northeastern Science Foundation, Troy, NY )

    1991-03-01

    Pervasive early- to late-diagenetic dolomitization of Lower Ordovician Ellenburger carbonates in the deep Permian basin is recorded in core samples having present-day burial depths of 1.5 to 7.0 km. Fine-crystalline planar replacement dolomite formed during early diagenesis in a subtidal to peritidal setting under near-surface, low-temperature conditions, with Mg{sup 2+} for dolomitization of precursor lime mud supplied by diffusion from overlying seawater. During intermediate burial (500-2,000 m), medium- to coarse-crystalline planar-s dolomite replaced allochems and matrix, or occurred as void-filling. Burial-history and thermal maturation calculations suggest that deep-burial dolomite cementation occurred during the Late Pennsylvanian/Early Permian. Inter- and intracrystalline dissolution surfaces are observed within the paragenetic sequence. Major truncation surfaces between early replacement dolomites and later void-filling dolomites, and between planar and nonplanar dolomite cements are evidence for dolomite dissolution. Deep-discharge of meteoric fluids as a result of frequent periods of karsting in overlying strata, and long-distance fluid migration during the Ouachita orogeny from foreland basins to the south are invoked for sources of undersaturated fluids causing dolomite dissolution and creating matrix-porosity in the deep subsurface. Similar diagenetic relationships have been described from other deeply buried carbonate rocks elsewhere, indicating that trends and timing of dolomitization, dissolution and porosity formation, and cementation by late dolomite and calcite are intimately related to the evolution of sedimentary basins. The origin of massive dolostones such as the Ellenburger is best explained in the context of basin evolution, rather than by a single model of dolomite formation.

  19. A Scoping Analysis Of The Impact Of SiC Cladding On Late-Phase Accident Progression Involving Core–Concrete Interaction

    SciTech Connect (OSTI)

    Farmer, M. T.

    2015-11-01

    The overall objective of the current work is to carry out a scoping analysis to determine the impact of ATF on late phase accident progression; in particular, the molten core-concrete interaction portion of the sequence that occurs after the core debris fails the reactor vessel and relocates into containment. This additional study augments previous work by including kinetic effects that govern chemical reaction rates during core-concrete interaction. The specific ATF considered as part of this study is SiC-clad UO2.

  20. Chromosome Damage and Cell Proliferation Rates in In Vitro Irradiated Whole Blood as Markers of Late Radiation Toxicity After Radiation Therapy to the Prostate

    SciTech Connect (OSTI)

    Beaton, Lindsay A.; Ferrarotto, Catherine; Marro, Leonora; Samiee, Sara; Malone, Shawn; Grimes, Scott; Malone, Kyle; Wilkins, Ruth C.

    2013-04-01

    Purpose: In vitro irradiated blood samples from prostate cancer patients showing late normal tissue damage were examined for lymphocyte response by measuring chromosomal aberrations and proliferation rate. Methods and Materials: Patients were selected from a randomized trial evaluating the optimal timing of dose-escalated radiation and short-course androgen deprivation therapy. Of 438 patients, 3% experienced grade 3 late radiation proctitis and were considered to be radiosensitive. Blood samples were taken from 10 of these patients along with 20 matched samples from patients with grade 0 proctitis. The samples were irradiated at 6 Gy and, along with control samples, were analyzed for dicentric chromosomes and excess fragments per cell. Cells in first and second metaphase were also enumerated to determine the lymphocyte proliferation rate. Results: At 6 Gy, there were statistically significant differences between the radiosensitive and control cohorts for 3 endpoints: the mean number of dicentric chromosomes per cell (3.26 0.31, 2.91 0.32; P=.0258), the mean number of excess fragments per cell (2.27 0.23, 1.43 0.37; P<.0001), and the proportion of cells in second metaphase (0.27 0.10, 0.46 0.09; P=.0007). Conclusions: These results may be a valuable indicator for identifying radiosensitive patients and for tailoring radiation therapy.

  1. Asymptomatic and late-onset ornithine transcarbamylase deficiency caused by a A208T mutation: Clinical, biochemical and DNA analyses in a four-generation family

    SciTech Connect (OSTI)

    Ausems, M.G.E.M.; Bakker, E.; Kneppers, A.L.J.

    1997-01-20

    We describe a 4-generation family in which a previously healthy 10-year-old boy died of late-onset ornithine transcarbamylase (OTC) deficiency. Pedigree analysis and allopurinol loading tests in female relatives were not informative. A missense mutation (A208T) in the OTC gene was detected in the deceased patient and in several clinically healthy male and female relatives, the oldest male being 97 years old. OTC deficiency was established in autopsy liver tissue of the propositus and liver biopsy samples of his sister, mother, and a maternal uncle. The males had 4% and 6% residual activity, respectively, the females 58% and 67%, respectively. The observed relation between the mutation and the decreased OTC activity in liver tissue of these subjects suggests that the mutation is a deleterious one. Late-onset, {open_quotes}mild{close_quotes} OTC deficiency can have a fatal or a favorable outcome. The disease can segregate undetected in families. 16 refs., 1 fig., 1 tab.

  2. NuSTAR OBSERVATIONS OF GRB130427A ESTABLISH A SINGLE COMPONENT SYNCHROTRON AFTERGLOW ORIGIN FOR THE LATE OPTICAL TO MULTI-GEV EMISSION

    SciTech Connect (OSTI)

    Kouveliotou, C.; Racusin, J. L.; Gehrels, N.; McEnery, J. E.; Zhang, W. W.; Bellm, E.; Harrison, F. A.; Vianello, G.; Oates, S.; Fryer, C. L.; Boggs, S. E.; Craig, W. W.; Christensen, F. E.; Dermer, C. D.; Hailey, C. J.; Melandri, A.; Tagliaferri, G.; Mundell, C. G.; Stern, D. K. E-mail: granot@openu.ac.il

    2013-12-10

    GRB130427A occurred in a relatively nearby galaxy; its prompt emission had the largest GRB fluence ever recorded. The afterglow of GRB130427A was bright enough for the Nuclear Spectroscopic Telescope ARray (NuSTAR) to observe it in the 3-79keV energy range long after its prompt emission (?1.5 and 5days). This range, where afterglow observations were previously not possible, bridges an important spectral gap. Combined with Swift, Fermi, and ground-based optical data, NuSTAR observations unambiguously establish a single afterglow spectral component from optical to multi-GeV energies a day after the event, which is almost certainly synchrotron radiation. Such an origin of the late-time Fermi/Large Area Telescope >10GeV photons requires revisions in our understanding of collisionless relativistic shock physics.

  3. BANYAN. V. A SYSTEMATIC ALL-SKY SURVEY FOR NEW VERY LATE-TYPE LOW-MASS STARS AND BROWN DWARFS IN NEARBY YOUNG MOVING GROUPS

    SciTech Connect (OSTI)

    Gagn, Jonathan; Lafrenire, David; Doyon, Ren; Malo, Lison; Artigau, tienne

    2015-01-10

    We present the BANYAN All-Sky Survey (BASS) catalog, consisting of 228 new late-type (M4-L6) candidate members of nearby young moving groups (YMGs) with an expected false-positive rate of ?13%. This sample includes 79 new candidate young brown dwarfs and 22 planetary-mass objects. These candidates were identified through the first systematic all-sky survey for late-type low-mass stars and brown dwarfs in YMGs. We cross-matched the Two Micron All Sky Survey and AllWISE catalogs outside of the galactic plane to build a sample of 98,970 potential ?M5 dwarfs in the solar neighborhood and calculated their proper motions with typical precisions of 5-15 mas yr{sup 1}. We selected highly probable candidate members of several YMGs from this sample using the Bayesian Analysis for Nearby Young AssociatioNsII tool (BANYANII). We used the most probable statistical distances inferred from BANYANII to estimate the spectral type and mass of these candidate YMG members. We used this unique sample to show tentative signs of mass segregation in the AB Doradus moving group and the Tucana-Horologium and Columba associations. The BASS sample has already been successful in identifying several new young brown dwarfs in earlier publications, and will be of great interest in studying the initial mass function of YMGs and for the search of exoplanets by direct imaging; the input sample of potential close-by ?M5 dwarfs will be useful to study the kinematics of low-mass stars and brown dwarfs and search for new proper motion pairs.

  4. Identifying the ionically bound cell wall and intracellular glycoside hydrolases in late growth stage Arabidopsis stems: Implications for the genetic engineering of bioenergy crops

    SciTech Connect (OSTI)

    Wei, Hui; Brunecky, Roman; Donohoe, Bryon S.; Ding, Shi -You; Ciesielski, Peter N.; Yang, Shihui; Tucker, Melvin P.; Himmel, Michael E.

    2015-05-13

    Identifying the cell wall-ionically bound glycoside hydrolases (GHs) in Arabidopsis stems is important for understanding the regulation of cell wall integrity. For cell wall proteomics studies, the preparation of clean cell wall fractions is a challenge since cell walls constitute an open compartment, which is more likely to contain a mixture of intracellular and extracellular proteins due to cell leakage at the late growth stage. Here, for this study, we utilize a CaCl2-extraction procedure to isolate non-structural proteins from Arabidopsis whole stems, followed by the in-solution and in-gel digestion methods coupled with Nano-LC-MS/MS, bioinformatics and literature analyses. This has led to the identification of 75 proteins identified using the in-solution method and 236 proteins identified by the in-gel method, among which about 10% of proteins predicted to be secreted. Together, eight cell wall proteins, namely AT1G75040, AT5G26000, AT3G57260, AT4G21650, AT3G52960, AT3G49120, AT5G49360, and AT3G14067, were identified by the in-solution method; among them, three were the GHs (AT5G26000, myrosinase 1, GH1; AT3G57260, β-1,3-glucanase 2, GH17; AT5G49360, bifunctional XYL 1/α-L-arabinofuranosidase, GH3). Moreover, four more GHs: AT4G30270 (xyloglucan endotransferase, GH16), AT1G68560 (bifunctional α-l-arabinofuranosidase/XYL, GH31), AT1G12240 (invertase, GH32) and AT2G28470 (β-galactosidase 8, GH35), were identified by the in-gel solution method only. Notably, more than half of above identified GHs are xylan- or hemicellulose-modifying enzymes, and will likely have an impact on cellulose accessibility, which is a critical factor for downstream enzymatic hydrolysis of plant tissues for biofuels production. Finally, the implications of these cell wall proteins identified at the late growth stage for the genetic engineering of bioenergy crops are discussed.

  5. Individualized 3D Reconstruction of Normal Tissue Dose for Patients With Long-term Follow-up: A Step Toward Understanding Dose Risk for Late Toxicity

    SciTech Connect (OSTI)

    Ng, Angela; Brock, Kristy K.; Sharpe, Michael B.; Department of Radiation Oncology, University of Toronto, Toronto, Ontario ; Moseley, Joanne L.; Craig, Tim; Department of Radiation Oncology, University of Toronto, Toronto, Ontario ; Hodgson, David C.

    2012-11-15

    Purpose: Understanding the relationship between normal tissue dose and delayed radiation toxicity is an important component of developing more effective radiation therapy. Late outcome data are generally available only for patients who have undergone 2-dimensional (2D) treatment plans. The purpose of this study was to evaluate the accuracy of 3D normal tissue dosimetry derived from reconstructed 2D treatment plans in Hodgkin's lymphoma (HL) patients. Methods and Materials: Three-dimensional lung, heart, and breast volumes were reconstructed from 2D planning radiographs for HL patients who received mediastinal radiation therapy. For each organ, a reference 3D organ was modified with patient-specific structural information, using deformable image processing software. Radiation therapy plans were reconstructed by applying treatment parameters obtained from patient records to the reconstructed 3D volumes. For each reconstructed organ mean dose (D{sub mean}) and volumes covered by at least 5 Gy (V{sub 5}) and 20Gy (V{sub 20}) were calculated. This process was performed for 15 patients who had both 2D and 3D planning data available to compare the reconstructed normal tissue doses with those derived from the primary CT planning data and also for 10 historically treated patients with only 2D imaging available. Results: For patients with 3D planning data, the normal tissue doses could be reconstructed accurately using 2D planning data. Median differences in D{sub mean} between reconstructed and actual plans were 0.18 Gy (lungs), -0.15 Gy (heart), and 0.30 Gy (breasts). Median difference in V{sub 5} and V{sub 20} were less than 2% for each organ. Reconstructed 3D dosimetry was substantially higher in historical mantle-field treatments than contemporary involved-field mediastinal treatments: average D{sub mean} values were 15.2 Gy vs 10.6 Gy (lungs), 27.0 Gy vs 14.3 Gy (heart), and 8.0 Gy vs 3.2 Gy (breasts). Conclusions: Three-dimensional reconstruction of absorbed dose to

  6. Identifying the ionically bound cell wall and intracellular glycoside hydrolases in late growth stage Arabidopsis stems: Implications for the genetic engineering of bioenergy crops

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Wei, Hui; Brunecky, Roman; Donohoe, Bryon S.; Ding, Shi -You; Ciesielski, Peter N.; Yang, Shihui; Tucker, Melvin P.; Himmel, Michael E.

    2015-05-13

    Identifying the cell wall-ionically bound glycoside hydrolases (GHs) in Arabidopsis stems is important for understanding the regulation of cell wall integrity. For cell wall proteomics studies, the preparation of clean cell wall fractions is a challenge since cell walls constitute an open compartment, which is more likely to contain a mixture of intracellular and extracellular proteins due to cell leakage at the late growth stage. Here, for this study, we utilize a CaCl2-extraction procedure to isolate non-structural proteins from Arabidopsis whole stems, followed by the in-solution and in-gel digestion methods coupled with Nano-LC-MS/MS, bioinformatics and literature analyses. This has ledmore » to the identification of 75 proteins identified using the in-solution method and 236 proteins identified by the in-gel method, among which about 10% of proteins predicted to be secreted. Together, eight cell wall proteins, namely AT1G75040, AT5G26000, AT3G57260, AT4G21650, AT3G52960, AT3G49120, AT5G49360, and AT3G14067, were identified by the in-solution method; among them, three were the GHs (AT5G26000, myrosinase 1, GH1; AT3G57260, β-1,3-glucanase 2, GH17; AT5G49360, bifunctional XYL 1/α-L-arabinofuranosidase, GH3). Moreover, four more GHs: AT4G30270 (xyloglucan endotransferase, GH16), AT1G68560 (bifunctional α-l-arabinofuranosidase/XYL, GH31), AT1G12240 (invertase, GH32) and AT2G28470 (β-galactosidase 8, GH35), were identified by the in-gel solution method only. Notably, more than half of above identified GHs are xylan- or hemicellulose-modifying enzymes, and will likely have an impact on cellulose accessibility, which is a critical factor for downstream enzymatic hydrolysis of plant tissues for biofuels production. Finally, the implications of these cell wall proteins identified at the late growth stage for the genetic engineering of bioenergy crops are discussed.« less

  7. Impact of TBI on late effects in children treated by megatherapy for Stage IV neuroblastoma. A study of the French Society of Pediatric oncology

    SciTech Connect (OSTI)

    Flandin, Isabelle; Michon, Jean; Pinkerton, Ross; Coze, Carole; Stephan, Jean Louis; Fourquet, Bernard; Valteau-Couanet, Dominique; Bergeron, Christophe; Philip, Thierry; Carrie, Christian . E-mail: carrie@lyon.fnclcc.fr

    2006-04-01

    Purpose: To determine the contribution of total body irradiation (TBI) to late sequelae in children treated with high-dose chemotherapy and autologous bone marrow transplantation for Stage IV neuroblastoma. Patients and Methods: We compared two populations that were similar with regard to age, stage, pre-autologous bone marrow transplantation chemotherapy (CT) regimen, period of treatment, and follow-up (12 years). The TBI group (n = 32) received TBI as part of the megatherapy procedure (1982-1993), whereas the CT group (n 30) received conditioning without TBI (1985-1992). Analysis 12 years later focused on growth, weight and corpulence (body mass index) delay; hormonal deficiencies; liver, kidney, heart, ear, eye, and dental sequelae; school performance; and the incidence of secondary tumors. Results: Impact of TBI was most marked in relation to growth and weight delay, although the mean delay was not severe, probably because of treatment with growth hormones. Other consequences of TBI were thyroid insufficiency, cataracts, and a high incidence of secondary tumors. Hearing loss and dental agenesis were more prominent in the group treated with CT alone. No differences were observed in school performance. Conclusion: The most frequent side effects of TBI were cataracts, thyroid insufficiency, and growth delay, but more worrying is the risk of secondary tumors. Because of the young mean age of patients and the toxicity of TBI regimens without any survival advantage, regimens without TBI are preferable in the management of Stage IV neuroblastoma.

  8. SpeX spectroscopy of unresolved very low mass binaries. II. Identification of 14 candidate binaries with late-M/early-L and T dwarf components

    SciTech Connect (OSTI)

    Bardalez Gagliuffi, Daniella C.; Burgasser, Adam J.; Nicholls, Christine P.; Gelino, Christopher R.; Looper, Dagny L.; Schmidt, Sarah J.; Cruz, Kelle; West, Andrew A.; Gizis, John E.; Metchev, Stanimir

    2014-10-20

    Multiplicity is a key statistic for understanding the formation of very low mass (VLM) stars and brown dwarfs. Currently, the separation distribution of VLM binaries remains poorly constrained at small separations (≤1 AU), leading to uncertainty in the overall binary fraction. We approach this problem by searching for late-M/early-L plus T dwarf spectral binaries whose combined light spectra exhibit distinct peculiarities, allowing for separation-independent identification. We define a set of spectral indices designed to identify these systems, and we use a spectral template fitting method to confirm and characterize spectral binary candidates from a library of 815 spectra from the SpeX Prism Spectral Libraries. We present 11 new binary candidates, confirm 3 previously reported candidates, and rule out 2 previously identified candidates, all with primary and secondary spectral types in the range M7-L7 and T1-T8, respectively. We find that subdwarfs and blue L dwarfs are the primary contaminants in our sample and propose a method for segregating these sources. If confirmed by follow-up observations, these systems may add to the growing list of tight separation binaries, whose orbital properties may yield further insight into brown dwarf formation scenarios.

  9. Internal energy dissipation of gamma-ray bursts observed with Swift: Precursors, prompt gamma-rays, extended emission, and late X-ray flares

    SciTech Connect (OSTI)

    Hu, You-Dong; Liang, En-Wei; Xi, Shao-Qiang; Peng, Fang-Kun; Lu, Rui-Jing; Lü, Lian-Zhong; Zhang, Bing E-mail: Zhang@physics.unlv.edu

    2014-07-10

    We jointly analyze the gamma-ray burst (GRB) data observed with Burst Alert Telescope (BAT) and X-ray Telescope on board the Swift mission to present a global view on the internal energy dissipation processes in GRBs, including precursors, prompt gamma-ray emission, extended soft gamma-ray emission, and late X-ray flares. The Bayesian block method is utilized to analyze the BAT light curves to identify various emission episodes. Our results suggest that these emission components likely share the same physical origin, which is the repeated activation of the GRB central engine. What we observe in the gamma-ray band may be a small part of more extended underlying activities. The precursor emission, which is detected in about 10% of Swift GRBs, is preferably detected in those GRBs that have a massive star core-collapse origin. The soft extended emission tail, on the other hand, is preferably detected in those GRBs that have a compact star merger origin. Bright X-ray emission is detected during the BAT quiescent phases prior to subsequent gamma-ray peaks, implying that X-ray emission may be detectable prior the BAT trigger time. Future GRB alert instruments with soft X-ray capability are essential for revealing the early stages of GRB central engine activities, and shedding light on jet composition and the jet launching mechanism in GRBs.

  10. THERMAL EMISSION IN THE EARLY X-RAY AFTERGLOWS OF GAMMA-RAY BURSTS: FOLLOWING THE PROMPT PHASE TO LATE TIMES

    SciTech Connect (OSTI)

    Friis, Mette [Centre for Astrophysics and Cosmology, Science Institute, University of Iceland, Dunhagi 5, 107 Reykjavik (Iceland); Watson, Darach, E-mail: mef4@hi.is, E-mail: darach@dark-cosmology.dk [Dark Cosmology Centre, Niels Bohr Institute, University of Copenhagen, Juliane Maries Vej 30, DK-2100 Copenhagen O (Denmark)

    2013-07-01

    Thermal radiation, peaking in soft X-rays, has now been detected in a handful of gamma-ray burst (GRB) afterglows and has to date been interpreted as shock break-out of the GRB's progenitor star. We present a search for thermal emission in the early X-ray afterglows of a sample of Swift bursts selected by their brightness in X-rays at early times. We identify a clear thermal component in eight GRBs and track the evolution. We show that at least some of the emission must come from highly relativistic material since two show an apparent super-luminal expansion of the thermal component. Furthermore, we determine very large luminosities and high temperatures for many of the components-too high to originate in a supernova shock break-out. Instead, we suggest that the component may be modeled as late photospheric emission from the jet, linking it to the apparently thermal component observed in the prompt emission of some GRBs at gamma-ray and hard X-ray energies. By comparing the parameters from the prompt emission and the early afterglow emission, we find that the results are compatible with the interpretation that we are observing the prompt quasi-thermal emission component in soft X-rays at a later point in its evolution.

  11. Ultrasonic Nakagami-parameter characterization of parotid-gland injury following head-and-neck radiotherapy: A feasibility study of late toxicity

    SciTech Connect (OSTI)

    Yang, Xiaofeng; Wu, Ning; Wang, Yuefeng; Tridandapani, Srini; School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332; Winship Cancer Institute, Emory University, Atlanta, Georgia 30322 ; Beitler, Jonathan J.; Yu, David S.; Curran, Walter J.; Liu, Tian; Bruner, Deborah W.; Winship Cancer Institute, Emory University, Atlanta, Georgia 30322; School of Nursing, Emory University, Atlanta, Georgia 30322

    2014-02-15

    Purpose: The study aims to investigate whether Nakagami parametersestimated from the statistical distribution of the backscattered ultrasound radio-frequency (RF) signalscould provide a means for quantitative characterization of parotid-gland injury resulting from head-and-neck radiotherapy. Methods: A preliminary clinical study was conducted with 12 postradiotherapy patients and 12 healthy volunteers. Each participant underwent one ultrasound study in which ultrasound scans were performed in the longitudinal, i.e., vertical orientation on the bilateral parotids. For the 12 patients, the mean radiation dose to the parotid glands was 37.7 9.5 Gy, and the mean follow-up time was 16.3 4.8 months. All enrolled patients experienced grade 1 or 2 late salivary-gland toxicity (RTOG/EORTC morbidity scale). The normal parotid glands served as the control group. The Nakagami-scaling and Nakagami-shape parameters were computed from the RF data to quantify radiation-induced parotid-gland changes. Results: Significant differences in Nakagami parameters were observed between the normal and postradiotherapy parotid glands. Compared with the control group, the Nakagami-scaling parameter of the postradiotherapy group decreased by 25.8% (p < 0.001), and the Nakagami-shape parameter decreased by 31.3% (p < 0.001). The area under the receiver operating characteristic curve was 0.85 for the Nakagami-scaling parameter and was 0.95 for the Nakagami-shape parameter, which further demonstrated the diagnostic efficiency of the Nakagami parameters. Conclusions: Nakagami parameters could be used to quantitatively measure parotid-gland injury following head-and-neck radiotherapy. Moreover, the clinical feasibility was demonstrated and this study provides meaningful preliminary data for future clinical investigation.

  12. Zircon and apatite fission-track evidence for an Early Permian thermal peak and relatively rapid Late Permian cooling in the Appalachian Basin

    SciTech Connect (OSTI)

    Roden, M.K. . Dept. of Earth and Environmental Science); Wintsch, R.P. . Dept. of Geological Sciences)

    1992-01-01

    New zircon fission-track ages compliment published apatite fission-track ages in the Appalachian Basin to narrowly constrain its thermal history. Geologic evidence can only constrain timing of the thermal peak to be younger than late Pennsylvanian sediments ([approximately] 300 Ma) and older than Mesozoic sediments in the Newark and Gettysburg Basins ([approximately] 210 Ma). Apatite fission-track ages as old as 246 Ma require the Alleghanian thermal peak to have been pre-Triassic. Preliminary data on reset zircon fission-track ages from middle Paleozoic sediments range from 255 to 290 Ma. Zircon fission-track apparent ages from samples younger and structurally higher than these are not reset. Thus, the oldest reset zircon fission-track age constraints the time of the Alleghanian thermal peak to be earliest Permian. Rates of post-Alleghanian cooling have not been well-constrained by geologic data and could be very slow. The difference between apatite and zircon fission-track ages for most of the samples range from 100--120 m.y. reflecting Permo-Triassic cooling of only 1 C/m.y. However, one sample with one of the oldest apatite ages, 245 Ma, yields one of the younger zircon ages of 255 Ma. This requires cooling rates of 10 C/m.y. and uplift rates of [approximately] 0.5 mm/yr. Collectively, these data support an early Permian thermal peak and a two-stage cooling history, consisting of > 100 C cooling (> 8 km denundation) in the Permian followed by relatively slow cooling and exhumation throughout the Mesozoic.

  13. Fluvial and deltaic facies and environments of the late permian back-reef shelves of the Permian Basin of Texas and New Mexico

    SciTech Connect (OSTI)

    Mazzullo, J. )

    1993-02-01

    The Artesia Group is a sequence of carbonates, evaporites, and clastics that was deposited across the back-reef shelves of the Permian Basin during late Permian time. There has been some controversy over the depositional environments of the clastic members of the Artesia Group and the role of sea level fluctuations in their accumulation. However, the results of a regional core study of the Queen Formation of the Artesia Group indicate that they were largely deposited in desert fluvial and deltaic environments during low-stands of sea level. Three fluvial-deltaic facies are recognized within the clastic members of the Queen. The first consists of medium to very find sandstones and silty sandstones with cross-beds, ripple cross-laminae, and planar and wavy laminae. This facies forms wavy sheets that thicken and thin along linear trends, and was deposited in sandy braided streams. The second facies consists of very find to fine sandstones, silty sandstones, and siltstones with ripple cross-laminae, planar and wavy laminae, cross-beds, clay drapes and pedogenetic cutans, as well as siltstones and silty mudstones with haloturbation structures and evaporite nodules. This facies forms thick planar sheets, and was deposited in fluvial sandflats and adjacent fluvial-dominated continental sabkhas. The third facies consists of cyclic deposits of haloturbated silty mudstones that grade into siltstones and very fine sandstones with crossbeds, planar and wavy laminae, haloturbation structures and evaporite nodules. Each cycle forms a lobate body that is bounded by carbonates or evaporites and which was deposited in sheet deltas that formed along the landward margins of a back-reef lagoon.

  14. Late Holocene shoreline behavior in embayments of Lake Michigan: Influence of quasi-periodic lake-level variations and sediment supply

    SciTech Connect (OSTI)

    Thompson, T.A.; Baedke, S.J. (Indiana Univ., Bloomington, IN (United States). Indiana Geological Survey)

    1994-04-01

    Lake Michigan contains numerous former embayments into glacial deposits or bedrock. Many of the embayments contain dunes, spits, and captured lakes, but others contain arcuate strandplains of beach ridges. The strandplains are a geologic record of shoreline behavior and lake-level variation throughout the late Holocene. The larger strandplains show similar long-term patterns of beach-ridge development. The similar patterns are expected because variations in lake level are a primary control on shoreline behavior, and all embayments would have experienced relatively the same lake-level changes. Some variations in the long-term pattern of shoreline development do occur between strandplains. These dissimilarities are primarily a function of different rates of sediment supply to the shoreline of each embayment. Beach-ridge development within embayments can be represented on a rate of water level change versus rate of sediment supply diagram (Curray diagram) as three superimposed ovals on the positive rate of sediment supply side of the diagram. The three stacked ovals represent the three quasi-periodic lake-level variations defined by Thompson (1992) and show the position of the shoreline for a given time within the Curray diagram fields. For shorelines with a high rate of sediment supply, only the 30-year quasi-periodic variation would reach the aggradation line. For shorelines having significantly less sediment supply, rising lake level on the 150- and 600-year variations would force the 30-year oval across the aggradation line and well into the depositional and possibly the erosional transgression fields. Under these conditions erosion would occur that may remove, stack, or at least prevent one or more beach ridges from being developed.

  15. Dosimetric difference amongst 3 techniques: TomoTherapy, sliding-window intensity-modulated radiotherapy (IMRT), and RapidArc radiotherapy in the treatment of late-stage nasopharyngeal carcinoma (NPC)

    SciTech Connect (OSTI)

    Lee, Francis Kar-ho Yip, Celia Wai-yi; Cheung, Frankie Chun-hung; Leung, Alex Kwok-cheung; Chau, Ricky Ming-chun; Ngan, Roger Kai-cheong

    2014-04-01

    To investigate the dosimetric difference amongst TomoTherapy, sliding-window intensity-modulated radiotherapy (IMRT), and RapidArc radiotherapy in the treatment of late-stage nasopharyngeal carcinoma (NPC). Ten patients with late-stage (Stage III or IV) NPC treated with TomoTherapy or IMRT were selected for the study. Treatment plans with these 3 techniques were devised according to departmental protocol. Dosimetric parameters for organ at risk and treatment targets were compared between TomoTherapy and IMRT, TomoTherapy and RapidArc, and IMRT and RapidArc. Comparison amongst the techniques was done by statistical tests on the dosimetric parameters, total monitor unit (MU), and expected delivery time. All 3 techniques achieved similar target dose coverage. TomoTherapy achieved significantly lower doses in lens and mandible amongst the techniques. It also achieved significantly better dose conformity to the treatment targets. RapidArc achieved significantly lower dose to the eye and normal tissue, lower total MU, and less delivery time. The dosimetric advantages of the 3 techniques were identified in the treatment of late-stage NPC. This may serve as a guideline for selection of the proper technique for different clinical cases.

  16. Predictors of Grade 3 or Higher Late Bowel Toxicity in Patients Undergoing Pelvic Radiation for Cervical Cancer: Results From a Prospective Study

    SciTech Connect (OSTI)

    Chopra, Supriya; Dora, Tapas; Chinnachamy, Anand N.; Thomas, Biji; Kannan, Sadhna; Engineer, Reena; Mahantshetty, Umesh; Phurailatpam, Reena; Paul, Siji N.; Shrivastava, Shyam Kishore

    2014-03-01

    Purpose: The present study investigates relationship between dosevolume parameters and severe bowel toxicity after postoperative radiation treatment (PORT) for cervical cancer. Methods and Materials: From June 2010 to December 2012, a total of 71 patients undergoing PORT were included. Small bowel (SB) and large bowel (LB) loops were contoured 2cm above the target volume. The volume of SB and LB that received 15Gy, 30Gy, and 40Gy was calculated (V15 SB, V15 LB, V30 SB, V30 LB, V40 SB, V 40 LB). On follow-up, bowel toxicity was scored using Common Terminology Criteria for Adverse Events (CTCAE), version 3.0. A reciever operating characteristic (ROC) curve identified volume thresholds that predicted for grade 3 or higher toxicity with highest specificity. All data was dichotomized across these identified cut-off values. Univariate and multivariate analysis was performed using SPSS, version15. Results: The median patient age was 47years (range, 35-65years). Of the 71 patients, 46 received image-guided intensity modulated radiation therapy, and 25 received conformal radiation (50Gy in 25 fractions for 5weeks). Overall, 63 of 71 patients received concurrent chemotherapy. On a median follow-up of 18months (range, 8-29months), grade 2 or higher bowel toxicity was seen in 22 of 71 patients (30.9%) and grade 3 or higher bowel toxicity was seen in 9 patients (12.6%). On univariate analysis, V15 SB <275 cc (P=.01), V30 SB <190 cc (P=.02), V40 SB <150 cc (P=.01), and V15 LB <250 cc (P=.03), and V40 LB <90 cc (P=.04) predicted for absence of grade 3 or higher toxicity. No other patient- or treatment-related factors were statistically significant. On multivariate analysis, only V15 SB (P=.002) and V15 LB (P=.03) were statistically significant. Conclusions: V 15Gy SB and LB are independent predictors of late grade 3 or higher toxicity. Restricting V15 SB and V15 LB to <275 cc and <250 cc can reduce grade 3 or higher toxicity to less than 5%.

  17. Extended (5-year) Outcomes of Accelerated Partial Breast Irradiation Using MammoSite Balloon Brachytherapy: Patterns of Failure, Patient Selection, and Dosimetric Correlates for Late Toxicity

    SciTech Connect (OSTI)

    Vargo, John A.; Verma, Vivek; Kim, Hayeon; Kalash, Ronny; Heron, Dwight E.; Johnson, Ronald; Beriwal, Sushil

    2014-02-01

    Purpose: Accelerated partial breast irradiation (APBI) with balloon and catheter-based brachytherapy has gained increasing popularity in recent years and is the subject of ongoing phase III trials. Initial data suggest promising local control and cosmetic results in appropriately selected patients. Long-term data continue to evolve but are limited outside of the context of the American Society of Breast Surgeons Registry Trial. Methods and Materials: A retrospective review of 157 patients completing APBI after breast-conserving surgery and axillary staging via high-dose-rate {sup 192}Ir brachytherapy from June 2002 to December 2007 was made. APBI was delivered with a single-lumen MammoSite balloon-based applicator to a median dose of 34 Gy in 10 fractions over a 5-day period. Tumor coverage and critical organ dosimetry were retrospectively collected on the basis of computed tomography completed for conformance and symmetry. Results: At a median follow-up time of 5.5 years (range, 0-10.0 years), the 5-year and 7-year actuarial incidences of ipsilateral breast control were 98%/98%, of nodal control 99%/98%, and of distant control 99%/99%, respectively. The crude rate of ipsilateral breast recurrence was 2.5% (n=4); of nodal failure, 1.9% (n=3); and of distant failure, 0.6% (n=1). The 5-year and 7-year actuarial overall survival rates were 89%/86%, with breast cancerspecific survival of 100%/99%, respectively. Good to excellent cosmetic outcomes were achieved in 93.4% of patients. Telangiectasia developed in 27% of patients, with 1-year, 3-year, and 5-year actuarial incidence of 7%/24%/33%; skin dose >100% significantly predicted for the development of telangiectasia (50% vs 14%, P<.0001). Conclusions: Long-term single-institution outcomes suggest excellent tumor control, breast cosmesis, and minimal late toxicity. Skin toxicity is a function of skin dose, which may be ameliorated with dosimetric optimization afforded by newer multicatheter brachytherapy applicators

  18. Formation of short-lived radionuclides in the protoplanetary disk during late-stage irradiation of a volatile-rich reservoir

    SciTech Connect (OSTI)

    Jacobsen, B; Matzel, J; Hutcheon, I D; Krot, A N; Yin, Q -; Nagashima, K; Ramon, E; Weber, P; Ishii, H; Ciesla, F

    2010-11-30

    The origin of short-lived (t{sub 1/2} < 5 Myr) and now extinct radionuclides ({sup 10}Be, {sup 26}Al, {sup 36}Cl, {sup 41}Ca, {sup 53}Mn, {sup 60}Fe; hereafter SLRs) is fundamental to understanding the formation of the early solar system. Two distinct classes of models have been proposed to explain the origin of SLRs: (1) injection from a nearby stellar source (e.g., supernova, asymptotic giant branch star or Wolf-Rayet star) and (2) solar energetic particle irradiation of dust and gas near the proto-Sun. Recent studies have demonstrated that {sup 36}Cl was extant in the early solar system. However, its presence, initial abundance and the noticeable decoupling from {sup 26}Al raise serious questions about the origin of SLRs. Here we report {sup 36}Cl-{sup 36}S and {sup 26}Al-{sup 26}Mg systematics for wadalite and grossular, secondary minerals in a calcium-aluminum-rich inclusion (CAI) from the CV chondrite Allende that allow us to reassess the origin of SLRs. The inferred abundance of {sup 36}Cl in wadalite, corresponding to a {sup 36}Cl/{sup 35}Cl ratio of (1.81 {+-} 0.13) x 10{sup -5}, is the highest {sup 36}Cl abundance reported in any early solar system material. The high level of {sup 36}Cl in wadalite and the absence of {sup 26}Al ({sup 26}Al/{sup 27}Al {le} 3.9 x 10{sup -6}) in co-existing grossular indicates that (1) {sup 36}Cl formed by late-stage solar energetic particle irradiation and (2) the production of {sup 36}Cl, recorded by secondary minerals, is unrelated to the origin of {sup 26}Al and other SLRs ({sup 10}Be, {sup 53}Mn) recorded by primary minerals of CAIs and chondrules. We conclude that 36Cl was produced by solar energetic particle irradiation of a volatile-rich reservoir in an optically thin protoplanetary disk adjacent to the accretion region of the CV chondrite parent asteroid.

  19. Late Toxicity and Patient Self-Assessment of Breast Appearance/Satisfaction on RTOG 0319: A Phase 2 Trial of 3-Dimensional Conformal Radiation Therapy-Accelerated Partial Breast Irradiation Following Lumpectomy for Stages I and II Breast Cancer

    SciTech Connect (OSTI)

    Chafe, Susan; Moughan, Jennifer; McCormick, Beryl; Wong, John; Pass, Helen; Rabinovitch, Rachel; Arthur, Douglas W.; Petersen, Ivy; White, Julia; Vicini, Frank A.

    2013-08-01

    Purpose: Late toxicities and cosmetic analyses of patients treated with accelerated partial breast irradiation (APBI) on RTOG 0319 are presented. Methods and Materials: Patients with stages I to II breast cancer ?3 cm, negative margins, and ?3 positive nodes were eligible. Patients received three-dimensional conformal external beam radiation therapy (3D-CRT; 38.5 Gy in 10 fractions twice daily over 5 days). Toxicity and cosmesis were assessed by the patient (P), the radiation oncologist (RO), and the surgical oncologist (SO) at 3, 6, and 12 months from the completion of treatment and then annually. National Cancer Institute Common Terminology Criteria for Adverse Events, version 3.0, was used to grade toxicity. Results: Fifty-two patients were evaluable. Median follow-up was 5.3 years (range, 1.7-6.4 years). Eighty-two percent of patients rated their cosmesis as good/excellent at 1 year, with rates of 64% at 3 years. At 3 years, 31 patients were satisfied with the treatment, 5 were not satisfied but would choose 3D-CRT again, and none would choose standard radiation therapy. The worst adverse event (AE) per patient reported as definitely, probably, or possibly related to radiation therapy was 36.5% grade 1, 50% grade 2, and 5.8% grade 3 events. Grade 3 AEs were all skin or musculoskeletal-related. Treatment-related factors were evaluated to potentially establish an association with observed toxicity. Surgical bed volume, target volume, the number of beams used, and the use of bolus were not associated with late cosmesis. Conclusions: Most patients enrolled in RTOG 0319 were satisfied with their treatment, and all would choose to have the 3D-CRT APBI again.

  20. Late Paleozoic structural evolution of Permian basin

    SciTech Connect (OSTI)

    Ewing, T.E.

    1984-04-01

    The southern Permian basin is underlain by the NNW-trending Central Basin disturbed belt of Wolfcamp age (Lower Permian), the deep Delaware basin to its west, and the shallower Midland basin to its eat. The disturbed belt is highly segmented with zones of left-lateral offset. Major segments from south to north are: the Puckett-Grey Ranch zone; the Fort Stockton uplift; the Monahans transverse zone; the Andector ridges and the Eunice ridge; the Hobbs transverse zone; and the Tatum ridges, which abut the broad Roosevelt uplift to the north. The disturbed belt may have originated along rift zones of either Precambrian or Cambrian age. The extent of Lower and Middle Pennsylvanian deformation is unclear; much of the Val Verde basin-Ozona arch structure may have formed then. The main Wolfcamp deformation over thrust the West Texas crustal block against the Delaware block, with local denudation of the uplifted edge and eastward-directed backthrusting into the Midland basin. Latter in the Permian, the area was the center of a subcontinental bowl of subsidence - the Permian basin proper. The disturbed belt formed a pedestal for the carbonate accumulations which created the Central Basin platform. The major pre-Permian reservoirs of the Permian basin lie in large structural and unconformity-bounded traps on uplift ridges and domes. Further work on the regional structural style may help to predict fracture trends, to assess the timing of oil migration, and to evaluate intrareservoir variations in the overlying Permian giant oil fields.

  1. Aerial photographic interpretation of lineaments and faults in late Cenozoic deposits in the eastern parts of the Saline Valley 1:100, 000 quadrangle, Nevada and California, and the Darwin Hills 1:100, 000 quadrangle, California

    SciTech Connect (OSTI)

    Reheis, M.C.

    1991-09-01

    Faults and fault-related lineaments in Quaternary and late Tertiary deposits in the southern part of the Walker Lane are potentially active and form patterns that are anomalous compared to those in most other areas of the Great Basin. Two maps at a scale of 1:100,000 summarize information about lineaments and faults in the area around and southwest of the Death Valley-Furnace Creek fault system based on extensive aerial-photo interpretation, limited field interpretation, limited field investigations, and published geologic maps. There are three major fault zones and two principal faults in the Saline Valley and Darwin Hills 1:100,000 quadrangles. (1) The Death Valley-Furnace Creek fault system and (2) the Hunter Mountain fault zone are northwest-trending right-lateral strike-slip fault zones. (3) The Panamint Valley fault zone and associated Towne Pass and Emigrant faults are north-trending normal faults. The intersection of the Hunter Mountain and Panamint Valley fault zones is marked by a large complex of faults and lineaments on the floor of Panamint Valley. Additional major faults include (4) the north-northwest-trending Ash Hill fault on the west side of Panamint Valley, and (5) the north-trending range-front Tin Mountain fault on the west side of the northern Cottonwood Mountains. The most active faults at present include those along the Death Valley-Furnace Creek fault system, the Tin Mountain fault, the northwest and southeast ends of the Hunter Mountain fault zone, the Ash Hill fault, and the fault bounding the west side of the Panamint Range south of Hall Canyon. Several large Quaternary landslides on the west sides of the Cottonwood Mountains and the Panamint Range apparently reflect slope instability due chiefly to rapid uplift of these ranges. 16 refs.

  2. Millennial-scale ocean acidification and late Quaternary

    SciTech Connect (OSTI)

    Riding, Dr Robert E; Liang, Liyuan; Braga, Dr Juan Carlos

    2014-01-01

    Ocean acidification by atmospheric carbon dioxide has increased almost continuously since the last glacial maximum (LGM), 21 000 years ago. It is expected to impair tropical reef development, but effects on reefs at the present day and in the recent past have proved difficult to evaluate. We present evidence that acidification has already significantly reduced the formation of calcified bacterial crusts in tropical reefs. Unlike major reef builders such as coralline algae and corals that more closely control their calcification, bacterial calcification is very sensitive to ambient changes in carbonate chemistry. Bacterial crusts in reef cavities have declined in thickness over the past 14 000 years with largest reduction occurring 12 000 10 000 years ago. We interpret this as an early effect of deglacial ocean acidification on reef calcification and infer that similar crusts were likely to have been thicker when seawater carbonate saturation was increased during earlier glacial intervals, and thinner during interglacials. These changes in crust thickness could have substantially affected reef development over glacial cycles, as rigid crusts significantly strengthen framework and their reduction would have increased the susceptibility of reefs to biological and physical erosion. Bacterial crust decline reveals previously unrecognized millennial-scale acidification effects on tropical reefs. This directs attention to the role of crusts in reef formation and the ability of bioinduced calcification to reflect changes in seawater chemistry. It also provides a long-term context for assessing anticipated anthropogenic effects.

  3. Late Cretaceous extension in the hinterland of the Sevier thrust...

    Open Energy Info (EERE)

    Sevier thrust belt, northwestern Utah and southern Idaho Abstract Cover rocks of the Raft River metamorphic core complex, located in the Sevier belt hinterland, preserve a...

  4. Galileon gravity and its relevance to late time cosmic acceleration

    SciTech Connect (OSTI)

    Gannouji, Radouane; Sami, M.

    2010-07-15

    We consider the covariant Galileon gravity taking into account the third order and fourth order scalar field Lagrangians L{sub 3}({pi}) and L{sub 4}({pi}), consisting of three and four {pi}'s with four and five derivatives acting on them, respectively. The background dynamical equations are set up for the system under consideration and the stability of the self-accelerating solution is demonstrated in a general setting. We extended this study to the general case of the fifth order theory. For the spherically symmetric static background, we spell out conditions for the suppression of fifth force effects mediated by the Galileon field {pi}. We study field perturbations in the fixed background and investigate the conditions for their causal propagation. We also briefly discuss metric fluctuations and derive an evolution equation for matter perturbations in Galileon gravity.

  5. Silica diagenesis in Santa Cruz mudstone, Late Miocene, California

    SciTech Connect (OSTI)

    El-Sabbagh, D.

    1987-05-01

    The silica-rich upper Miocene Santa Cruz Mudstone is similar to the Miocene Monterey Formation. Previous studies have suggested the Santa Cruz Mudstone was not buried deeply nor had it undergone extensive diagenesis. Because opaline diagenesis is temperature dependent, the author examined the silica diagenesis of the Santa Cruz Mudstone using scanning electron microscopy and x-ray diffraction methods to study its burial history. In a series of samples from Santa Cruz to Davenport, California (over 16 km), opal-CT is the dominant silica phase present and clay minerals are notably absent. The d(101)-spacing values of opal-CT range from 4.11 A (Santa Cruz area) to 4.06 A (north of Santa Cruz), exhibiting the complete range of d(101)-spacing values found in opal-CT zones. Scanning electron micrographs of crystalline microtextures show rosettes of opal-CT (lepispheres) in cavities of samples with medium to high d(101)-spacing values. The morphology of lepisphere crystallites grades from bladed to spiny with decreasing d(101)-spacing values, reflecting an internal crystal ordering with increased diagenesis. Further diagenetic changes occurred in a sample with 4.06 A d(101)-spacing where incipient quartz crystals signal the initial conversion of opal-CT to microcrystalline quartz. Silica diagenesis demonstrates that burial temperatures surpassed the range of opal-A to opal-CT conversion and approached conversion temperatures (55/sup 0/C to 110/sup 0/C) of opal-CT to microcrystalline quartz. The conversion occurred when the Santa Cruz Mudstone was buried over 1900 m (depth calculated from a geohistory diagram). This burial temperature brings the Santa Cruz Mudstone within the oil generation window, and could account for the presence of hydrocarbons in the unit.

  6. Observational constraints on late-time {lambda}(t) cosmology

    SciTech Connect (OSTI)

    Carneiro, S.; Pigozzo, C.; Dantas, M. A.; Alcaniz, J. S.

    2008-04-15

    The cosmological constant {lambda}, i.e., the energy density stored in the true vacuum state of all existing fields in the Universe, is the simplest and the most natural possibility to describe the current cosmic acceleration. However, despite its observational successes, such a possibility exacerbates the well-known {lambda} problem, requiring a natural explanation for its small, but nonzero, value. In this paper we study cosmological consequences of a scenario driven by a varying cosmological term, in which the vacuum energy density decays linearly with the Hubble parameter, {lambda}{proportional_to}H. We test the viability of this scenario and study a possible way to distinguish it from the current standard cosmological model by using recent observations of type Ia supernova (Supernova Legacy Survey Collaboration), measurements of the baryonic acoustic oscillation from the Sloan Digital Sky Survey, and the position of the first peak of the cosmic microwave background angular spectrum from the three-year Wilkinson Microwave Anisotropy Probe.

  7. Transition duct with late injection in turbine system

    DOE Patents [OSTI]

    LeBegue, Jeffrey Scott; Pentecost, Ronnie Ray; Flanagan, James Scott; Kim, Won -Wook; McMahan, Kevin Weston

    2015-09-15

    A system for supplying an injection fluid to a combustor is disclosed. The system includes a transition duct comprising an inlet, an outlet, and a passage extending between the inlet and the outlet and defining a longitudinal axis, a radial axis, and a tangential axis. The outlet of the transition duct is offset from the inlet along the longitudinal axis and the tangential axis. The passage defines a combustion chamber. The system further includes a tube providing fluid communication for the injection fluid to flow through the transition duct and into the combustion chamber.

  8. Late Cenozoic volcanism, geochronology, and structure of the...

    Open Energy Info (EERE)

    rocks that were erupted during two periods, as defined by K-Ar dating: (1) 4.0--2.5 m.y., approx.31 km3 of basalt, rhyodacite, dacite, andesite, and rhyolite, in descending...

  9. Middle-Late Permian mass extinction on land

    SciTech Connect (OSTI)

    Retallack, G.J.; Metzger, C.A.; Greaver, T.; Jahren, A.H.; Smith, R.M.H.; Sheldon, N.D.

    2006-11-15

    The end-Permian mass extinction has been envisaged as the nadir of biodiversity decline due to increasing volcanic gas emissions over some 9 million years. We propose a different tempo and mechanism of extinction because we recognize two separate but geologically abrupt mass extinctions on land, one terminating the Middle Permian (Guadalupian) at 260.4 Ma and a later one ending the Permian Period at 251 Ma. Our evidence comes from new paleobotanical, paleopedological, and carbon isotopic studies of Portal Mountain, Antarctica, and comparable studies in the Karoo Basin, South Africa. Extinctions have long been apparent among marine invertebrates at both the end of the Guadalupian and end of the Permian, which were also times of warm-wet greenhouse climatic transients, marked soil erosion, transition from high- to low-sinuosity and braided streams, soil stagnation in wetlands, and profound negative carbon isotope anomalies. Both mass extinctions may have resulted from catastrophic methane outbursts to the atmosphere from coal intruded by feeder dikes to flood basalts, such as the end-Guadalupian Emeishan Basalt and end-Permian Siberian Traps.

  10. Aerial photographic interpretation of lineaments and faults in late cenozoic deposits in the Eastern part of the Benton Range 1:100,000 quadrangle and the Goldfield, Last Chance Range, Beatty, and Death Valley Junction 1:100,000 quadrangles, Nevada and California

    SciTech Connect (OSTI)

    Reheis, M.C.; Noller, J.S.

    1991-09-01

    Lineaments and faults in Quaternary and late Tertiary deposits in the southern part of the Walker Lane are potentially active and form patterns that are anomalous with respect to the typical fault patterns in most of the Great Basin. Little work has been done to identify and characterize these faults, with the exception of those in the Death Valley-Furnace Creek (DVFCFZ) fault system and those in and near the Nevada Test Site. Four maps at a scale of 1:100,000 summarize the existing knowledge about these lineaments and faults based on extensive aerial-photo interpretation, limited field investigations, and published geologic maps. The lineaments and faults in all four maps can be divided geographically into two groups. The first group includes west- to north-trending lineaments and faults associated with the DVFCFZ and with the Pahrump fault zone in the Death Valley Junction quadrangle. The second group consists of north- to east-northeast-trending lineaments and faults in a broad area that lies east of the DVFCFZ and north of the Pahrump fault zone. Preliminary observations of the orientations and sense of slip of the lineaments and faults suggest that the least principle stress direction is west-east in the area of the first group and northwest-southeast in the area of the second group. The DVFCFZ appears to be part of a regional right-lateral strike-slip system. The DVFCFZ steps right, accompanied by normal faulting in an extensional zone, to the northern part of the Walker Lane a the northern end of Fish Lake Valley (Goldfield quadrangle), and appears to step left, accompanied by faulting and folding in a compressional zone, to the Pahrump fault zone in the area of Ash Meadows (Death Valley Junction quadrangle). 25 refs.

  11. Yiii%sz Rockwell

    Office of Legacy Management (LM)

    these activities we were known as the Atomics International Divi- sion of North American Aviation, Inc. In September 1962 we shipped 409 kilograms of uranium enriched to...

  12. Property:NumberOfLowEmissionDevelopmentStrategiesExamples | Open...

    Open Energy Info (EERE)

    sionDevelopmentStrategiesExamples Property Type Number Retrieved from "http:en.openei.orgwindex.php?titleProperty:NumberOfLowEmissionDevelopmentStrategiesExamples&oldid323715...

  13. Hydropower Vision Chapter 1: Introducing the Hydropower Vision

    Broader source: Energy.gov (indexed) [DOE]

    ... valuation of system-wide grid reliability and stability services; and recognition and valuation of societal benefits from avoided power-sector air pollution and GHG emis- sions. ...

  14. Materials Data on LaTe2 (SG:129) by Materials Project

    SciTech Connect (OSTI)

    Kristin Persson

    2015-02-09

    Computed materials data using density functional theory calculations. These calculations determine the electronic structure of bulk materials by solving approximations to the Schrodinger equation. For more information, see https://materialsproject.org/docs/calculations

  15. LATE SPECTRAL EVOLUTION OF THE EJECTA AND REVERSE SHOCK IN SN...

    Office of Scientific and Technical Information (OSTI)

    The external X-ray illumination also explains the edge-brightened morphology of the ejecta ... Country of Publication: United States Language: English Subject: 79 ASTROPHYSICS, ...

  16. The Thermal Regime Of The San Juan Basin Since Late Cretaceous...

    Open Energy Info (EERE)

    Times And Its Relationship To San Juan Mountains Thermal Sources Abstract Heat-flow and coal-maturation data suggest that the thermal history of the San Juan Basin has...

  17. Constraining dark matter late-time energy injection: decays and p-wave annihilations

    SciTech Connect (OSTI)

    Diamanti, Roberta; Mena, Olga; Palomares-Ruiz, Sergio; Vincent, Aaron C.; Lopez-Honorez, Laura E-mail: llopezho@vub.ac.be E-mail: sergio.palomares.ruiz@ific.uv.es

    2014-02-01

    We use the latest cosmic microwave background (CMB) observations to provide updated constraints on the dark matter lifetime as well as on p-wave suppressed annihilation cross sections in the 1 MeV to 1 TeV mass range. In contrast to scenarios with an s-wave dominated annihilation cross section, which mainly affect the CMB close to the last scattering surface, signatures associated with these scenarios essentially appear at low redshifts (z∼<50) when structure began to form, and thus manifest at lower multipoles in the CMB power spectrum. We use data from Planck, WMAP9, SPT and ACT, as well as Lyman–α measurements of the matter temperature at z ∼ 4 to set a 95% confidence level lower bound on the dark matter lifetime of ∼ 4 × 10{sup 25} s for m{sub χ} = 100 MeV. This bound becomes lower by an order of magnitude at m{sub χ} = 1 TeV due to inefficient energy deposition into the intergalactic medium. We also show that structure formation can enhance the effect of p-wave suppressed annihilation cross sections by many orders of magnitude with respect to the background cosmological rate, although even with this enhancement, CMB constraints are not yet strong enough to reach the thermal relic value of the cross section.

  18. LATE-TIME DUST EMISSION FROM THE TYPE IIn SUPERNOVA 1995N

    SciTech Connect (OSTI)

    Van Dyk, Schuyler D.

    2013-05-15

    Type IIn supernovae (SNe IIn) have been found to be associated with significant amounts of dust. These core-collapse events are generally expected to be the final stage in the evolution of highly massive stars, either while in an extreme red supergiant phase or during a luminous blue variable phase. Both evolutionary scenarios involve substantial pre-supernova mass loss. I have analyzed the SN IIn 1995N in MCG -02-38-017 (Arp 261), for which mid-infrared archival data obtained with the Spitzer Space Telescope in 2009 ({approx}14.7 yr after explosion) and with the Wide-field Infrared Survey Explorer in 2010 ({approx}15.6-16.0 yr after explosion) reveal a luminous ({approx}2 Multiplication-Sign 10{sup 7} L{sub Sun }) source detected from 3.4 to 24 {mu}m. These observations probe the circumstellar material, set up by pre-SN mass loss, around the progenitor star and indicate the presence of {approx}0.05-0.12 M{sub Sun} of pre-existing, cool dust at {approx}240 K. This is at least a factor {approx}10 lower than the dust mass required to be produced from SNe at high redshift, but the case of SN 1995N lends further evidence that highly massive stars could themselves be important sources of dust.

  19. Late Cenozoic Ring Faulting and Volcanism in the Coso Range Area...

    Open Energy Info (EERE)

    to the surface during the past few million years. Author Wendell A. Duffield Published Journal Geology, 1975 DOI Not Provided Check for DOI availability: http:crossref.org...

  20. The climatic and hydrologic history of southern Nevada during the late Quaternary

    SciTech Connect (OSTI)

    Forester, R.M.; Bradbury, J.P.; Carter, C.; Elvidge-Tuma, A.B.; Hemphill, M.L.; Lundstrom, S.C.; Mahan, S.A.; Marshall, B.D.; Neymark, L.A.; Paces, J.B.; Sharpe, S.E.; Whelan, J.F.; Wigand, P.E.

    1999-09-21

    Understanding climate change during the expected life span of a potential high-level nuclear-waste repository at Yucca Mountain, Nevada, requires estimates of future climate boundary conditions. These climate boundary conditions are governed by changes in the Earth's orbital properties (eccentricity, obliquity, precession) that determine insolation. Subcycles of the 400,000 year insolation-controlled climate cycles last approximately 100,000 years. This report describes the changes which have occurred in the climatic history of Southern Nevada during the past 400,000 years. These changes provide a basis for understanding the changes which may occur during the long-term future in this area.

  1. Modified gravity a la Galileon: Late time cosmic acceleration and observational constraints

    SciTech Connect (OSTI)

    Ali, Amna; Sami, M.; Gannouji, Radouane

    2010-11-15

    In this paper we examine the cosmological consequences of fourth order Galileon gravity. We carry out detailed investigations of the underlying dynamics and demonstrate the stability of one de Sitter phase. The stable de Sitter phase contains a Galileon field {pi} which is an increasing function of time ({pi}>0). Using the required suppression of the fifth force, supernovae, Baryon acoustic oscillations, and CMB data, we constrain parameters of the model. We find that the {pi} matter coupling parameter {beta} is constrained to small numerical values such that {beta}<0.02. We also show that the parameters of the third and fourth order in the action (c{sub 3},c{sub 4}) are not independent and with reasonable assumptions, we obtain constraints on them. We investigate the growth history of the model and find that the subhorizon approximation is not allowed for this model. We demonstrate strong scale dependence of linear perturbations in the fourth order Galileon gravity.

  2. LATE-TIME OPTICAL EMISSION FROM CORE-COLLAPSE SUPERNOVAE (Journal...

    Office of Scientific and Technical Information (OSTI)

    and a decline in Halpha(O I+O II) which is broadly consistent with the view that the reverse shock has passed through the H envelope of the ejecta in many of these objects. ...

  3. Thermodynamic and Transport Properties of YTe3, LaTe3 and CeTe3

    SciTech Connect (OSTI)

    Ru, N.

    2011-08-19

    Measurements of heat capacity, susceptibility, and electrical resistivity are presented for single crystals of the charge density wave compounds YTe{sub 3}, LaTe{sub 3}, and CeTe{sub 3}. The materials are metallic to low temperatures, but have a small density of states due to the charge density wave gapping large portions of the Fermi surface. CeTe{sub 3} is found to be a weak Kondo lattice, with an antiferromagnetic ground state and T{sub N} = 2.8 K. The electrical resistivity of all three compounds is highly anisotropic, confirming the weak dispersion perpendicular to Te planes predicted by band structure calculations.

  4. OGLE-2008-BLG-355Lb: A massive planet around a late-type star

    SciTech Connect (OSTI)

    Koshimoto, N.; Sumi, T.; Fukagawa, M.; Shibai, H.; Udalski, A.; Bennett, D. P.; Bond, I. A.; Ling, C. H.; Rattenbury, N.; Botzler, C. S.; Freeman, M.; Abe, F.; Furusawa, K.; Itow, Y.; Masuda, K.; Matsubara, Y.; Fukui, A.; Muraki, Y.; Ohnishi, K.; Saito, To.; Collaboration: MOA Collaboration; OGLE Collaboration; and others

    2014-06-20

    We report the discovery of a massive planet, OGLE-2008-BLG-355Lb. The light curve analysis indicates a planet:host mass ratio of q = 0.0118 ± 0.0006 at a separation of 0.877 ± 0.010 Einstein radii. We do not measure a significant microlensing parallax signal and do not have high angular resolution images that could detect the planetary host star. Therefore, we do not have a direct measurement of the host star mass. A Bayesian analysis, assuming that all host stars have equal probability to host a planet with the measured mass ratio, implies a host star mass of M{sub h}=0.37{sub −0.17}{sup +0.30} M{sub ⊙} and a companion of mass M{sub P}=4.6{sub −2.2}{sup +3.7}M{sub J}, at a projected separation of r{sub ⊥}=1.70{sub −0.30}{sup +0.29} AU. The implied distance to the planetary system is D {sub L} = 6.8 ± 1.1 kpc. A planetary system with the properties preferred by the Bayesian analysis may be a challenge to the core accretion model of planet formation, as the core accretion model predicts that massive planets are far more likely to form around more massive host stars. This core accretion model prediction is not consistent with our Bayesian prior of an equal probability of host stars of all masses to host a planet with the measured mass ratio. Thus, if the core accretion model prediction is right, we should expect that follow-up high angular resolution observations will detect a host star with a mass in the upper part of the range allowed by the Bayesian analysis. That is, the host would probably be a K or G dwarf.

  5. Late Quaternary glacier sensitivity to temperature and precipitation distribution in the Southern Alps of New Zealand

    SciTech Connect (OSTI)

    Ann V. Rowan; Simon H. Brocklehurst; David M. Schultz; Mitchell A. Plummer; Leif S. Anderson; Neil F. Glasser

    2014-05-01

    Glaciers respond to climate variations and leave geomorphic evidence that represents an important terrestrial paleoclimate record. However, the accuracy of paleoclimate reconstructions from glacial geology is limited by the challenge of representing mountain meteorology in numerical models. Precipitation is usually treated in a simple manner and yet represents difficult-to-characterize variables such as amount, distribution, and phase. Furthermore, precipitation distributions during a glacial probably differed from present-day interglacial patterns. We applied two models to investigate glacier sensitivity to temperature and precipitation in the eastern Southern Alps of New Zealand. A 2-D model was used to quantify variations in the length of the reconstructed glaciers resulting from plausible precipitation distributions compared to variations in length resulting from change in mean annual air temperature and precipitation amount. A 1-D model was used to quantify variations in length resulting from interannual climate variability. Assuming that present-day interglacial values represent precipitation distributions during the last glacial, a range of plausible present-day precipitation distributions resulted in uncertainty in the Last Glacial Maximum length of the Pukaki Glacier of 17.1?km (24%) and the Rakaia Glacier of 9.3?km (25%), corresponding to a 0.5°C difference in temperature. Smaller changes in glacier length resulted from a 50% decrease in precipitation amount from present-day values (-14% and -18%) and from a 50% increase in precipitation amount (5% and 9%). Our results demonstrate that precipitation distribution can produce considerable variation in simulated glacier extents and that reconstructions of paleoglaciers should include this uncertainty.

  6. Crystallized alkali-silica gel in concrete from the late 1890s

    SciTech Connect (OSTI)

    Peterson, Karl . E-mail: cee@mtu.edu; Gress, David . E-mail: dlgress@unh.edu; Van Dam, Tom . E-mail: cee@mtu.edu; Sutter, Lawrence . E-mail: cee@mtu.edu

    2006-08-15

    The Elon Farnsworth Battery, a concrete structure completed in 1898, is in an advanced state of disrepair. To investigate the potential for rehabilitation, cores were extracted from the battery. Petrographic examination revealed abundant deposits of alkali silica reaction products in cracks associated with the quartz rich metasedimentary coarse aggregate. The products of the alkali silica reaction are variable in composition and morphology, including both amorphous and crystalline phases. The crystalline alkali silica reaction products are characterized by quantitative X-ray energy dispersive spectrometry (EDX) and X-ray diffraction (XRD). The broad extent of the reactivity is likely due to elevated alkali levels in the cements used.

  7. Late Pseudocoarctation Syndrome After Stent-Graft Implantation For Traumatic Aortic Rupture

    SciTech Connect (OSTI)

    Letocart, Vincent Fau, Georges Tirouvanziam, Ashok; Toquet, Claire; Al Habash, Oussama Guerin, Patrice; Rousseau, Herve; Crochet, Dominique

    2013-06-15

    The present observation illustrates an unusual complication occurring after stent-grafting (S-graft) for aortic isthmus rupture. A 22-year-old patient, treated by S-graft in the emergency department for traumatic aortic rupture, was readmitted 10 months later with pseudocoarctation syndrome. A membrane was found inside the stent-graft that had induced a pseudo-dissection, which caused the pseudocoarctation syndrome. Surgical treatment consisted of removing the stent-graft and membrane and replacing it with a vascular implant. The patient's clinical course was fair. The suggested mechanism was circumferential neoendothelialization of the stent-graft. Dehiscence caused the superior part of the membrane to drop into the lumen of the stent-graft creating a 'false channel' that compressed the 'true lumen' and induced 'pseudocoarctation' syndrome. The cause of the extensive neointimalization remains unexplained. Thoracic aortic stent-grafts require regular follow-up monitoring by angioscan or angio-magnetic resonance imaging.

  8. DOUBLETS AND DOUBLE PEAKS: LATE-TIME [O I] lambdalambda6300,...

    Office of Scientific and Technical Information (OSTI)

    ... Subject: 79 ASTROPHYSICS, COSMOLOGY AND ASTRONOMY; DUSTS; EMISSION; SCATTERING; SPECTRA; SUPERNOVAE BINARY STARS; ERUPTIVE VARIABLE STARS; STARS; VARIABLE STARS Word Cloud More ...

  9. Modeling of Late Blooming Phases and Precipitation Kinetics in Aging Reactor Pressure Vessel (RPV) Steels

    SciTech Connect (OSTI)

    Yongfeng Zhang; Pritam Chakraborty; S. Bulent Biner

    2013-09-01

    The principle work at the atomic scale is to develop a predictive quantitative model for the microstructure evolution of RPV steels under thermal aging and neutron radiation. We have developed an AKMC method for the precipitation kinetics in bcc-Fe, with Cu, Ni, Mn and Si being the alloying elements. In addition, we used MD simulations to provide input parameters (if not available in literature). MMC simulations were also carried out to explore the possible segregation/precipitation morphologies at the lattice defects. First we briefly describe each of the simulation algorithms, then will present our results.

  10. Late Cenozoic volcanism in the Lassen area, southernmost Cascade Range, California

    SciTech Connect (OSTI)

    Clynne, M.A.; Muffler, L.J.P.; Dalrymple, G.B. )

    1993-04-01

    Volcanism in the southernmost Cascade Range can be characterized on two scales. Regional volcanism is predominantly basaltic to andesitic, and hundreds of coalescing volcanoes of small volume (10[sup [minus]3] to 10[sup 1] km[sup 3]) with short lifetimes have built a broad platform. Superimposed on the regional volcanism are a few long-lived ([approximately]10[sup 6] years) much larger (>10 [sup 2] km[sup 3]) volcanic centers. Each of these larger centers consists of a basaltic-andesite to andesite composite cone and flanking silicic domes and flows. The evolution of these volcanic centers conforms to a generalized three-stage model during which a conspicuous edifice is constructed. Stages 1 and 2 comprise a dominantly andesitic composite cone; Stage 3 marks a change to dominantly silicic volcanism and is accompanied by development of a hydrothermal system in the permeable core of the andesitic composite cone. Subsequent fluvial and glacial erosion produces a caldera-like depression with a topographically high resistant rim of Stage 2 lavas surrounding the deeply eroded, hydrothermally altered core of the composite cone. Two types of basalt are recognized in the southernmost Cascades; medium-K calc-alkaline (CAB) and low-K olivine tholeiite (LKOT). CAB exhibits considerable geochemical diversity and is the parent magma for the volcanic-center lavas and the majority of the evolved regional lavas. LKOT is chemically homogeneous, and outcrops sporadically in association with extensional tectonics of the Basin and Range Province, and is related to Pleistocene encroachment of Basin-and-Range tectonics on the subduction-related volcanism of the Cascade Range.

  11. Reconstruction of a high-resolution late holocene arctic paleoclimate record from Colville River delta sediments.

    SciTech Connect (OSTI)

    Schreiner, Kathryn Melissa; Lowry, Thomas Stephen

    2013-10-01

    This work was partially supported by the Sandia National Laboratories,Laboratory Directed Research and Development' (LDRD) fellowship program in conjunction with Texas A&M University (TAMU). The research described herein is the work of Kathryn M. Schreiner (Katie') and her advisor, Thomas S. Bianchi and represents a concise description of Katie's dissertation that was submitted to the TAMU Office of Graduate Studies in May 2013 in partial fulfillment of her doctorate of philosophy degree. High Arctic permafrost soils contain a massive amount of organic carbon, accounting for twice as much carbon as what is currently stored as carbon dioxide in the atmosphere. However, with current warming trends this sink is in danger of thawing and potentially releasing large amounts of carbon as both carbon dioxide and methane into the atmosphere. It is difficult to make predictions about the future of this sink without knowing how it has reacted to past temperature and climate changes. This project investigated long term, fine scale particulate organic carbon (POC) delivery by the high-Arctic Colville River into Simpson's Lagoon in the near-shore Beaufort Sea. Modern POC was determined to be a mixture of three sources (riverine soils, coastal erosion, and marine). Downcore POC measurements were performed in a core close to the Colville River output and a core close to intense coastal erosion. Inputs of the three major sources were found to vary throughout the last two millennia, and in the Colville River core covary significantly with Alaskan temperature reconstructions.

  12. Sediment body quantification: Examples from a Late Permian mixed influence deltaic system, Bowen Basin, Australia

    SciTech Connect (OSTI)

    Falkner, A.; Fielding, C. )

    1990-05-01

    The Bowen basin open-cut coal mines of central Queensland, Australia, provide some of the best exposures of alluvial and fluviodeltaic sequences in the world. Within the Bowen basin coal is mined extensively along a strike length of 5-600 km exposing various parts of an Upper Permian terrestrial to shallow-marine sequence. Individual mines cover 10-30 km of strike and may work several different seams that are correlatable between mines. The project described here is aimed at providing a detailed database on facies geometry within coal-bearing alluvial and fluviodeltaic sequences of the Bowen basin. Data has been collected from the profusion of very large open-cut coal mine exposures in eastern Queensland, Australia, and rationalized into a form useful for hydrocarbon reservoir description. High-quality geometrical data is obtained from controlled photomosaics of highwalls supplemented by information from close-spaced borehole networks. Detailed information from core and accessible exposures allows accurate sedimentological interpretation. Interpretation of the German Creek Formation, one of the coalbearing units of the Bowen basin, suggests that accumulation occurred on an extensive lower delta plain, within a mixed (i.e., wave-tide-fluvial influenced) delta. Four facies have been identified, two of which are possible reservoirs: facies A, major channelized sandstone bodies (4-11 m thick and 0.5-5 km wide, elongate perpendicular to basin edge), interpreted as deltaic distributary channel fills; and facies B, tabular sandstone bodies (9-20 m thick tens of km in areal extent, elongate parallel to basin margin) internally dominated by hummocky cross-stratification, interpreted as proximal mouth bar deposits.

  13. Sedimentology and diagenesis of the Zechstein Ca2 carbonate, Late Permian, northwest Germany

    SciTech Connect (OSTI)

    Strohmenger, C.; Rockenbauch, K. ); Love, K.M.; Mitchell, J.C. )

    1993-09-01

    Carbonates of the second Zechstein cycle, the Stassfurt Carbonate (Ca2), constitute north Germany's most prolific carbonate gas play. The underlying Werra Anhydrite (A1) of the first Zechstein cycle and the overlying Basal Anhydrite (A2) of the second Zechstein cycle enclosed the reservoir. An erosional sequence boundary present at the top of the A1 sulfate platform separates the A1 from the overlying Ca2 carbonate platform. Ca2 thickness ranges from 30 to 80 m on the platform, 40 to 250 m on the slope, and 10 to 40 m in the basin. Following flooding of the underlying A1 sulfate platform (Ca2 maximum flooding), Ca2 shallow-water carbonates prograded basinward. Platform, upper slope, middle slope, and lower slope facies are recognized and are subdivided into 27 subfacies. Systematic trends in facies distribution are apparent on depositional dip-oriented well log cross sections. Trends in vertical succession of subfacies types, along with the good correlation between Ca2 facies and A1 thickness, enable mapping of the updip and downdip limits of the facies. Diagenesis is important in determining Ca2 reservoir quality. Reservoir rock is typically fair to good where it is dolomite. Early calcitization (dedolomitization) of the Ca2 yields poor to non-reservoir rocks. Although calcitization in general increases basinward, lateral prediction of mineralogy within individual Ca2 facies is difficult. A multivariate statistical investigation has been initiated to determine parameters, which are important in predicting trends in calcite distribution.

  14. Cyclostratigraphy and duration of the Yates Formation (Permian, Late Guadalupian) of the Permian Basin

    SciTech Connect (OSTI)

    Borer, J.M.; Harris, P.M. )

    1990-05-01

    Using log, core, and outcrop data, the authors have identified patterns in cyclic sequences of the mixed siliciclastic-carbonate Yates Formation of the Permian basin. A composite well log, representing the entire formation through a single sea level-sensitive facies tract, exhibits two orders of cyclicity with Milankovitch band periodicity. At the shelf margin, large-scale cycles consist of subequal dolomite- and siliciclastic-rich intervals. Small-scale cycles are carbonate and siliciclastic couplets that exhibit regular changes in lithology and thickness (bundling) that define the large-scale cycles. Cycle packaging changes across the shelf due to the updip (landward) pinch-out of high frequency carbonate intervals. Several lines of evidence suggest that the depositional cycles are the product of orbitally forced sea level fluctuations with 100- and 400-k.y. periods (Milankovitch eccentricity cycles). This implies that the five large-scale cycles present in the Yates represent about 2 m.y. of deposition. A lower frequency (third-order) sea level cycle was also active during Yates deposition. This 1.5- to 2-m.y. cycle is apparent from Fischer plots and a lithofacies cross section. The third-order cycle may be related to a low-frequency Milankovitch signal or tectonics. Fischer plots and stratigraphic analysis suggest that all the sea level fluctuations had relatively low magnitudes ranging from approximately 2 m for the 100-k.y. cycles, 8-12 m for the 400-k.y. cycles, and 5 m for the 1.5- to 2-m.y. cycle. The architecture of Yates Formation reservoirs is related to the stacking of depositional sequences during the three orders of sea-level fluctuations. In general, the low frequency (1.5-2 m.y.) cycle controlled the lateral position and reservoir quality of 400-k.y. depositional cycles (reservoir units); whereas, high-frequency (100 k.y.) sea level cycles controlled heterogeneity within reservoir units.

  15. Variscan fold belt and its foreland in western Europe from late Carboniferous to Permian time

    SciTech Connect (OSTI)

    Mascle, A.; Benard, F.; Cazes, M.; Le Gall, B.

    1988-08-01

    The Variscan front was emplaced in the Later Carboniferous with a south-to-north or southeast-to-northwest-trending vergence of thrusting. At the same time, folds were formed in the foreland. In England and southern Scotland, such structures were induced by an east-west direction of shortening, followed by a more subdued north-south compressive event. In Stephanian time, isolated basins developed on the Hercynian belt. In the Massif Central Marues Massif, they are closely related to transcurrent faults which developed in response to north-south-trending compressive stresses. The distribution of stresses completely changed in Early Permian time when extension dominated almost everywhere. Three kinds of basins developed at that time: those related to the relaxation of stresses on the Hercynian range, a north-south-trending rift system in the western United Kingdom and the North Sea, and a broad flexural evaporitic basin from eastern England to Poland.

  16. THE LINK BETWEEN LIGHT AND MASS IN LATE-TYPE SPIRAL GALAXY DISKS

    SciTech Connect (OSTI)

    Swaters, Robert A.; Bershady, Matthew A.; Martinsson, Thomas P. K.; Westfall, Kyle B.; Andersen, David R.; Verheijen, Marc A. W.

    2014-12-20

    We present the correlation between the extrapolated central disk surface brightness (?) and extrapolated central surface mass density (?) for galaxies in the DiskMass sample. This ?-? relation has a small scatter of 30% at the high surface brightness (HSB) end. At the low surface brightness (LSB) end, galaxies fall above the ?-? relation, which we attribute to their higher dark matter content. After correcting for the dark matter as well as for the contribution of gas and the effects of radial gradients in the disk, the LSB end falls back on the linear ?-? relation. The resulting scatter around the corrected ?-? relation is 25% at the HSB end and about 50% at the LSB end. The intrinsic scatter in the ?-? relation is estimated to be 10%-20%. Thus, if ? {sub K,} {sub 0} is known, the stellar surface mass density is known to within 10%-20% (random error). Assuming disks have an exponential vertical distribution of mass, the average ?{sub ?}{sup K} is 0.24 M {sub ?}/L {sub ?}, with an intrinsic scatter around the mean of at most 0.05 M {sub ?}/L {sub ?}. This value for ?{sub ?}{sup K} is 20% smaller than we found in Martinsson et al., mainly due to the correction for dark matter applied here. This small scatter means that among the galaxies in our sample, variations in scale height, vertical density profile shape, and/or the ratio of vertical over radial velocity dispersion must be small.

  17. CORRELATED SPECTRAL AND TEMPORAL BEHAVIOR OF LATE-TIME AFTERGLOWS OF GAMMA-RAY BURSTS

    SciTech Connect (OSTI)

    Dado, Shlomo; Dar, Arnon [Physics Department, Technion, Haifa 32000 (Israel)

    2012-12-20

    The cannonball (CB) model of gamma-ray bursts (GRBs) predicts that the asymptotic behavior of the spectral energy density of GRB afterglows is a power law in time and in frequency, and the difference between the temporal and spectral power-law indices, {alpha}{sub X} - {beta}{sub X}, is restricted to the values 0, 1/2, and 1. Here we report the distributions of the values {alpha}{sub X} and {beta}{sub X}, and their difference for a sample of 315 Swift GRBs. This sample includes all Swift GRBs that were detected before 2012 August 1, whose X-ray afterglow extended well beyond 1 day and the estimated error in {alpha}{sub X} - {beta}{sub X} was {<=}0.25. The values of {alpha}{sub X} were extracted from the CB-model fits to the entire light curves of their X-ray afterglow while the spectral index was extracted by the Swift team from the time-integrated X-ray afterglow of these GRBs. We found that the distribution of the difference {alpha}{sub X} - {beta}{sub X} for these 315 Swift GRBs has three narrow peaks around 0, 1/2, and 1 whose widths are consistent with being due to the measurement errors, in agreement with the CB-model prediction.

  18. Mini Z' Burst from Relic Supernova Neutrinos and Late NeutrinoMasses...

    Office of Scientific and Technical Information (OSTI)

    Language: English Word Cloud More Like This Full Text Journal Articles Find in Google Scholar Find in Google Scholar Search WorldCat Search WorldCat to find libraries that may hold ...

  19. SLA-74.0103 No For(:iqri

    Office of Scientific and Technical Information (OSTI)

    Antia ,craft b1issiJ.e (SIAM). A description of the optical system is included, and models of target radiant intensity, atmospheric transmis- sion, and background radiance...

  20. SECURING HARDWARE, SOFTWARE AND DATA

    Energy Savers [EERE]

    wish to thank Joree O'Neal and Rachel Smith for all their help and support with ... Lab; sion@cs.stonybrook.edu Smith, Sean; Dartmouth College; sws@cs.dartmouth.edu St. ...

  1. untitled

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... to model the effects of fast-neutron pulses on the gain ... sion's Office of New Reactors in performing license ... Tech Area 5 with a Sodium Reactor Fuel Debris ...

  2. LBL--29472 DE91

    Office of Scientific and Technical Information (OSTI)

    This work supported by the Director, Office 11 of Energy Research, Office of High Energy and Nuclear Physics, Nuclear Science Divi- sion, U. S. Department of Energy under con- ...

  3. Use Vapor Recompression to Recover Low-Pressure Waste Steam,...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... Conduct a Pinch Analysis Based on the actual application, there may be other options to vapor recompres- sion. The industry best practice is to conduct a pinch analysis on the ...

  4. TRUTeamWorks 08-05-04

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Waste Isolation Pilot Plant team Transportation and disposal ... engineer in the U.S. Naval Nuclear Propul- sion Program. ... To everyone else, thank you. John Gran The Safety Awareness ...

  5. X&h

    Office of Legacy Management (LM)

    ... 1945, effective as of the 1st day of Ray 1343, the partics hereto entered into ... JRZPRAS, said contract was tmnsferred to the Vnitcd States Atomic Energy Conn&sion ...

  6. Compliance, HQ GILMAD J&ILL STUDY

    Office of Legacy Management (LM)

    associated with the Ilanhattan Project andor early Atomic Energy Coaik5sion activities. ... Barium x-rays were pronounced in the corresponding x-ray spectra taken with the FIDLER ...

  7. microRNA Alterations Driving Acute and Late Stages of Radiation-Induced Fibrosis in a Murine Skin Model

    SciTech Connect (OSTI)

    Simone, Brittany A.; Ly, David; Savage, Jason E.; Hewitt, Stephen M.; Dan, Tu D.; Ylaya, Kris; Shankavaram, Uma; Lim, Meng; Jin, Lianjin; Camphausen, Kevin; Mitchell, James B.; Simone, Nicole L.

    2014-09-01

    Purpose: Although ionizing radiation is critical in treating cancer, radiation-induced fibrosis (RIF) can have a devastating impact on patients' quality of life. The molecular changes leading to radiation-induced fibrosis must be elucidated so that novel treatments can be designed. Methods and Materials: To determine whether microRNAs (miRs) could be responsible for RIF, the fibrotic process was induced in the right hind legs of 9-week old CH3 mice by a single-fraction dose of irradiation to 35Gy, and the left leg served as an unirradiated control. Fibrosis was quantified by measurements of leg length compared with control leg length. By 120days after irradiation, the irradiated legs were 20% (P=.013) shorter on average than were the control legs. Results: Tissue analysis was done on muscle, skin, and subcutaneous tissue from irradiated and control legs. Fibrosis was noted on both gross and histologic examination by use of a pentachrome stain. Microarrays were performed at various times after irradiation, including 7days, 14days, 50days, 90days, and 120days after irradiation. miR-15a, miR-21, miR-30a, and miR-34a were the miRs with the most significant alteration by array with miR-34a, proving most significant on confirmation by reverse transcriptase polymerase chain reaction, c-Met, a known effector of fibrosis and downstream molecule of miR-34a, was evaluated by use of 2cell lines: HCT116 and 1522. The cell lines were exposed to various stressors to induce miR changes, specifically ionizing radiation. Additionally, invitro transfections with pre-miRs and anti-miRs confirmed the relationship of miR-34a and c-Met. Conclusions: Our data demonstrate an inverse relationship with miR-34a and c-Met; the upregulation of miR-34a in RIF causes inhibition of c-Met production. miRs may play a role in RIF; in particular, miR-34a should be investigated as a potential target to prevent or treat this devastating side effect of irradiation.

  8. Analysis of In-Vessel Late Phase Melt Progression Using SCDAP/RELAP5/MOD3.3

    SciTech Connect (OSTI)

    Park, R.J.; Kim, S.B.; Kim, H.D. [Korea Atomic Energy Research Institute, Yuseong, P.O.Box 105, Daejeon, 305-600 (Korea, Republic of)

    2004-07-01

    High-pressure in-vessel melt progressions of the KSNP (Korean Standard Nuclear Power Plant) have been analyzed using the SCDAP/RELAP5/MOD3.3 computer code. The total loss of feed water (LOFW) to the steam generators with/without intentional RCS depressurization using the safety depressurization system (SDS) and the station blackout (SBO) have been simulated from transient initiation to reactor vessel failure. The SCDAP/RELAP5/MOD3.3 results have shown that the pressure boundary of the reactor coolant system did not fail before reactor vessel failure in the high-pressure sequences of the LOFW and the SBO transients of the KSNP. In all the high-pressure transients, approximately 20-30 % of the core material was melted and relocated to the lower plenum of the reactor vessel at the time of reactor vessel failure. Intentional RCS depressurization using the SDS for the total LOFW delays reactor vessel failure for approximately 5 hours by actuation of the safety injection tanks. At the time of reactor vessel failure, approximately 50-60 % of the fuel rod cladding was oxidized for the total LOFW and the SBO transients of the KSNP. (authors)

  9. Late Pleistocene and Holocene-Age Columbia River Sediments and Bedforms: Hanford Reach Area, Washington - Part 2

    SciTech Connect (OSTI)

    K.R. Fecht, T.E. Marceau

    2006-03-28

    This report presents the results of a geologic study conducted on the lower slopes of the Columbia River Valley in south-central Washington. The study was designed to investigate glaciofluvial and fluvial sediments and bedforms that are present in the river valley and formed subsequent to Pleistocene large-scale cataclysmic flooding of the region.

  10. Solar-Geophysical Data Number 537, May 1989. Part 1 (prompt reports). Data for April, March 1989, and late data

    SciTech Connect (OSTI)

    Coffey, H.E.

    1987-07-01

    Solar data are presented for March and April, 1989. The data include sunspot activity indices; solar flares in the H-alpha line; solar radio emissions at 3, 10, 21, and 43 cm; and mean solar magnetic fields.

  11. Giant fields of the late 80s associated with type [open quotes]A[close quotes] subduction in South America

    SciTech Connect (OSTI)

    Duval, B.; Cramez, C. ); Figuera, J. ); Lander, R. ); Hernandez, G. )

    1993-02-01

    About 10 billion bbl of recoverable oil have been found in these three fields for which the petroleum generating subsystem is very similar. The potential source rocks are the organic sediments associated with the major downlap surface of the post-Pangea continental encroachment sedimentary cycle, i.e., MFS 91, 5 Ma (La Luna formation). However, the concentrating physico-chemical petroleum subsystem is quite different. The El Furrial/Musipan field is associated with a Tertiary foredeep basin overlying a generating Atlantic type passive margin. On the other hand, Cusiana and Ceuta fields are associated with a Tertiary foredeep basin developed over a generating back-arc basin. The different stacking of sedimentary basins controls the migration/entrapment petroleum subsystem. In El Furrial/Musipan, decollement surfaces and their associated thrusts are predominant whereas, in Ceuta and Cusiana the majority of compressional structures are created by tectonic inversions. These tectonic settings create different petroleum systems: (a) supercharged with low impedance and lateral drainage in El Furrial/Musipan, (b) normally charged with high impedance and vertically drained in Ceuta and Cusiana area. Each case requires appropriated exploration approaches.

  12. An inverse Compton origin for the 55 GeV photon in the late afterglow of GRB 130907A

    SciTech Connect (OSTI)

    Tang, Qing-Wen; Wang, Xiang-Yu [School of Astronomy and Space Science, Nanjing University, Nanjing 210093 (China); Tam, Pak-Hin Thomas, E-mail: xywang@nju.edu.cn, E-mail: phtam@phys.nthu.edu.tw [Institute of Astronomy and Department of Physics, National Tsing Hua University, Hsinchu 30013, Taiwan (China)

    2014-06-20

    The extended high-energy gamma-ray (>100 MeV) emission which occurs well after the prompt gamma-ray bursts (GRBs) is usually explained as the afterglow synchrotron radiation. Here we report the analysis of Fermi Large Area Telescope observations of GRB 130907A. A 55 GeV photon compatible with the position of the burst was found about 5 hr after the prompt phase. The probability that this photon is associated with GRB 130907A is higher than 99.96%. The energy of this photon exceeds the maximum synchrotron photon energy at this time and its occurrence thus challenges the synchrotron mechanism as the origin for the extended high-energy >10 GeV emission. Modeling of the broadband spectral energy distribution suggests that such high energy photons can be produced by the synchrotron self-Compton emission of the afterglow.

  13. Super-massive planets around late-type starsthe case of OGLE-2012-BLG-0406Lb

    SciTech Connect (OSTI)

    Poleski, Rados?aw; Gould, Andrew; Udalski, Andrzej; Szyma?ski, Micha? K.; Soszy?ski, Igor; Kubiak, Marcin; Pietrzy?ski, Grzegorz; Koz?owski, Szymon; Pietrukowicz, Pawe?; Ulaczyk, Krzysztof; Skowron, Jan; Wyrzykowski, ?ukasz; Dong, Subo

    2014-02-10

    Super-Jupiter-mass planets should form only beyond the snow line of host stars. However, the core accretion theory of planetary formation does not predict super-Jupiters forming around low-mass hosts. We present a discovery of a 3.9 1.2 M {sub Jup} mass planet orbiting the 0.59 0.17 M {sub ?} star using the gravitational microlensing method. During the event, the projected separation of the planet and the star is 3.9 1.0 AU, i.e., the planet is significantly further from the host star than the snow line. This is the fourth such planet discovered using the microlensing technique and challenges the core accretion theory.

  14. Evidence for change in climate variability during the late-holocene inferred from a sequence of Lake Michigan dune ridges

    SciTech Connect (OSTI)

    Lichter, J. (Univ. of Minnesota, St. Paul, MN (United States))

    1994-06-01

    The timing of ridge formation at a sequence of northern Lake Michigan foredune ridges was calibrated with the historical lake-level record and with climate records to reconstruct a history of climate-related lake-level variation. Foredune ridges are constructed during receding and low lake levels related to regional drought. Shore recession during high lake levels may promote eolian erosion which modifies the shore-parallel foredune ridges into parabolic dunes. A chronology of ridge formation over the last 2400 years indicates that parabolic dunes developed only during periods of frequent ridge formation and drought. Analysis of ridge formation during the historical record of lake-level variation suggest that this association results from increase variability in regional water balances as opposed to variation in sediment supply. Periods of high variability in regional water balances occurred between 380 BC and AD 20, AD 20, AD 20-300, AD 880-990, AD 1180-1280, and AD 1520-1650.

  15. Membership Finland

    ScienceCinema (OSTI)

    None

    2011-04-25

    Le DG C.Rubbia et la vice présidente du conseil du Cern souhaite la bienvenue à l'adhésion de la Finlande, comme 15me membre du Cern depuis le 1. janvier 1991 en présence du secrétaire generale et de l'ambassadeur

  16. DOE/EIS-0132-F United States Department ...

    Broader source: Energy.gov (indexed) [DOE]

    ... T h e U . S. N u c l ea r R eg u l a to ry C omi s sion ( NR C ) wi l l c o n c u r in t h ... E . 2 . 1 3 ) . The dRAP sumary, however, omi ts hydra u l i c condu c t i v i ty v a l ...

  17. Press conference

    ScienceCinema (OSTI)

    None

    2011-04-25

    Exposés de plusieurs intervenants de la direction et du conseil, comme le Prof.Ramsey, président du conseil sur l'adhésion récente de la Finlande et le "boom" scientifique des pays de l'est.

  18. Title Geographic Distribution. Eumeces gilberti Rubricaudatus...

    National Nuclear Security Administration (NNSA)

    RL 10,0.3 km E ofCo.RoadDD(Sec.33,T52N.R26W).16July 1989. F. E. Blake & D. D. Smith. ... Conserv. Publ., 368 pp.). Submitted by DONALD D. SMITH, Divi- sion of Allergy & ...

  19. C. SIrENET

    Office of Legacy Management (LM)

    m. 61 12!?1/37 C. SIrENET PR jwnlrn RB-JUTA,000LffiBe kw4LV ID TM Ca#lsSION KSII~ ELECTRIC CL@'. VlTiiuFsf MRCS PL#il CMWIE-IELLa CYcLOTml FK

  20. COOLANT STABILIZED WITH KETONE

    DOE Patents [OSTI]

    Burr, J.G.; Strong, J.D.

    1961-11-21

    sion). U. S. Patent 3,009.88l. Nov. 2l, l06l. A method is given for inhibiting radiolytic damage to a polyphenyl composition undergoing nuclear irradiation, the polyphenyl composition initially consisting essentially of polyphenyls having 2 to 4 phenyl rings. The method comprises adding approximately 5 mole% anthraquinone to the polyphenyl composition. (AEC)

  1. SERENDIPITOUS DISCOVERY OF A MASSIVE cD GALAXY AT z = 1.096: IMPLICATIONS FOR THE EARLY FORMATION AND LATE EVOLUTION OF cD GALAXIES

    SciTech Connect (OSTI)

    Liu, F. S.; Guo Yicheng; Koo, David C.; Trump, Jonathan R.; Barro, Guillermo; Yesuf, Hassen; Faber, S. M.; Cheung, Edmond; Cassata, P.; Koekemoer, A. M.; Grogin, Norman A.; Pentericci, L.; Castellano, M.; Mao, Shude; Xia, X. Y.; Hathi, Nimish P.; Huang, Kuang-Han; Kocevski, Dale; McGrath, Elizabeth J.; and others

    2013-06-01

    We have made a serendipitous discovery of a massive ({approx}5 Multiplication-Sign 10{sup 11} M{sub Sun }) cD galaxy at z = 1.096 in a candidate-rich cluster in the Hubble Ultra Deep Field (HUDF) area of GOODS-South. This brightest cluster galaxy (BCG) is the most distant cD galaxy confirmed to date. Ultra-deep HST/WFC3 images reveal an extended envelope starting from {approx}10 kpc and reaching {approx}70 kpc in radius along the semimajor axis. The spectral energy distributions indicate that both its inner component and outer envelope are composed of an old, passively evolving (specific star formation rate <10{sup -4} Gyr{sup -1}) stellar population. The cD galaxy lies on the same mass-size relation as the bulk of quiescent galaxies at similar redshifts. The cD galaxy has a higher stellar mass surface density ({approx}M{sub *}/R{sub 50}{sup 2}) but a similar velocity dispersion ({approx}{radical}(M{sub *}/R{sub 50})) to those of more massive, nearby cDs. If the cD galaxy is one of the progenitors of today's more massive cDs, its size (R{sub 50}) and stellar mass have had to increase on average by factors of 3.4 {+-} 1.1 and 3.3 {+-} 1.3 over the past {approx}8 Gyr, respectively. Such increases in size and stellar mass without being accompanied by significant increases in velocity dispersion are consistent with evolutionary scenarios driven by both major and minor dissipationless (dry) mergers. If such cD envelopes originate from dry mergers, our discovery of even one example proves that some BCGs entered the dry merger phase at epochs earlier than z = 1. Our data match theoretical models which predict that the continuance of dry mergers at z < 1 can result in structures similar to those of massive cD galaxies seen today. Moreover, our discovery is a surprise given that the extreme depth of the HUDF is essential to reveal such an extended cD envelope at z > 1 and, yet, the HUDF covers only a minuscule region of sky ({approx}3.1 Multiplication-Sign 10{sup -8}). Adding that cDs are rare, our serendipitous discovery hints that such cDs may be more common than expected, perhaps even ubiquitous. Images reaching HUDF depths of more area (especially with cluster BCGs at z > 1) are needed to confirm this conjecture.

  2. Middle to Late Holocene Fluctuations of C3 and C4 Vegetation in a Northern New England Salt Marsh, Sprague Marsh, Phippsburg Maine

    SciTech Connect (OSTI)

    Johnson, B J; Moore, K A; Lehmann, C; Bohlen, C; Brown, T A

    2006-05-26

    A 3.1 meter sediment core was analyzed for stable carbon isotope composition of organic matter and higher plant leaf wax (HPLW) lipid biomarkers to determine Holocene shifts in C{sub 3} (higher high marsh) and C{sub 4} (low and/or high marsh) plant deposition at the Sprague River Salt Marsh, Phippsburg, Maine. The carbon isotope composition of the bulk sediment and the HPLW parallel each other throughout most of the core, suggesting that terrestrial plants are an important source of organic matter to the sediments, and diagenetic alteration of the bulk sediments is minimal. The current salt marsh began to form 2500 cal yr BP. Low and/or high C{sub 4} marsh plants dominated deposition at 2000 cal yr BP, 700 cal yr BP, and for the last 200 cal yr BP. Expansion of higher high marsh C{sub 3} plants occurred at 1300 and 600 cal yr BP. These major vegetation shifts result from a combination of changes in relative sea-level rise and sediment accumulation rates. Average annual carbon sequestration rates for the last 2500 years approximate 40 g C yr{sup -1} m{sup -2}, and are in strong agreement with other values published for the Gulf of Maine. Given that Maine salt marshes cover an area of {approx}79 km{sup 2}, they represent an important component of the terrestrial carbon sink. More detailed isotopic and age records from a network of sediment cores at Sprague Marsh are needed to truly evaluate the long term changes in salt marsh plant communities and the impact of more recent human activity, including global warming, on salt marsh vegetation.

  3. Boron neutron capture therapy: A guide to the understanding of the pathogenesis of late radiation damage to the rat spinal cord

    SciTech Connect (OSTI)

    Morris, G.M.; Whitehouse, E.M.; Hopewell, J.W. ); Coderre, J.A.; Micca, P. )

    1994-03-30

    Before the commencement of new boron neutron capture therapy (BNCT) clinical trials in Europe and North America, detailed information on normal tissue tolerance is required. In this study, the pathologic effects of BNCT on the central nervous system (CNS) have been investigated using a rat spinal cord model. The neutron capture agent used was [sup 10]B-enriched sodium mercaptoundecahydro-closo-dodecaborate (BSH), at a dosage of 100 mg/kg body weight. Rats were irradiated on the thermal beam at the Brookhaven Medical Research Reactor. The large spine of vertebra T[sub 2] was used as the lower marker of the irradiation field. Rats were irradiated with thermal neutrons alone to a maximum physical absorbed dose of 11.4 Gy, or with thermal neutrons in combination with BSH, to maximum absorbed physical doses of 5.7 Gy to the CNS parenchyma and 33.7 Gy to the blood in the vasculature of the spinal cord. An additional group of rats was irradiated with 250 kVp X-rays to a single dose of 35 Gy. Spinal cord pathology was examined between 5 and 12 months after irradiation. The physical dose of radiation delivered to the CNS parenchyma, using thermal neutron irradiation in the presence of BSH, was a factor of two to three lower than that delivered to the vascular endothelium, and could not account for the level of damage observed in the parenchyma. The histopathological observations of the present study support the hypothesis that the blood vessels, and the endothelial cells in particular, are the critical target population responsible for the lesions seen in the spinal cord after BNCT type irradiation and by inference, after more conventional irradiation modalities such as photons or fast neutrons. 30 refs., 6 figs., 1 tab.

  4. Possible flexural mechanisms for origins of extensive, ooid-rich, carbonate environments, middle and early late Mississippian, east-central United States

    SciTech Connect (OSTI)

    Ettensohn, F.R. )

    1989-08-01

    During the earliest Mississippian, much of east-central US was a deep-water black-shale basin formed due to subsidence accompanying Acadian tectonism; by the middle Mississippian, this basin had been transformed into a very shallow epeiric sea characterized by ooid-rich carbonates. This transformation probably occurred in two parts due to flexural mechanisms accompanying the end of the Acadian orogeny and the beginning of the Ouachita orogeny. In the eastern part of the basin, with the end of active Acadian deformational loading, lithospheric relaxation caused uplift and eastward migration of the Acadian peripheral bulge from near the Cincinnati arch into the Appalachian basin. By the middle Meramecian, this uplift and a concomitant infilling of the basin with post-orogenic clastics created an extensive shallow-water platform conducive to ooid deposition well into the Appalachian basin. In western parts of the cratonic black-shale basin, from the western flanks of the Cincinnati arch to the eastern flanks of the Transcontinental arch, any infilling with postorogenic Acadian clastics was minor. However, by the Kinderhook-Osage transition, apparent collision and subduction leading to the Ouachita orogeny had begun, and with the inception of collision, the entire foreland as far north as the Illinois basin was upwarped by the cratonward (north and northeast) migration of the accompany peripheral bulge. As a result, by the early Meramecian, shallow-water conditions favorable for oolitic-carbonate deposition prevailed throughout the area.

  5. Depositional and erosional coastal processes during the late postglacial sea-level rise: An example from the central Tyrrhenian continental shelf (Italy)

    SciTech Connect (OSTI)

    Tortora, P.

    1996-03-01

    A transgressive systems tract (TST) deposit on the inner continental shelf of the south Tuscany region (central Tyrrhenian Sea, Italy) formed during the last postglacial sea-level rise. Its small-scale stratigraphy has been detailed using high-resolution seismic profiles, gravity cores, and grab samples. The TST deposit overlies a lowstand unconformity, shows a tabular geometry, and comprises three internal architectures of beach facies. Because the lateral distribution of these vertical successions is not random, but parallel to the coast, each architecture represents an individual sedimentary stage during sea-level rise. However, all architectures were formed via shoreface retreat in response to the landward migration of a beach complex over the unconformity. During this migration the beach system was characterized by a source diastem located in the surf zone and by two sediment dispersal systems. One moved the eroded sand over the flat back-barrier palustrine area by storm washover, while the other transported part of this sand to the lower shoreface, forming a reworked sand sheet above the older and inactive source diastem (ravinement surface). The TST architectures originated from a transgressive succession of beach facies, differentiated according to the intensity of shoreface retreat. Architecture A represents a low preservation potential of the original beach complex, Architecture B relatively high preservation, and Architecture C no preservation. The intensity of erosion and the consequent preservation potential were totally controlled by antecedent topography.

  6. Illitization of diagenetic kaolinite-to-dickite conversion series: Late-stage diagenesis of the Lower Permian Rotliegene sandstone reservoir, offshore of the Netherlands

    SciTech Connect (OSTI)

    Lanson, B.; Beaufort, D.; Berger, G.; Baradat, J.; Lacharpagne, J.C.

    1996-05-01

    This paper describes the diagenetic evolution of clay minerals in the Rotliegend sandstone reservoir under contrasting burial histories in the Broad Fourteens basin (Dutch sector, Southern North Sea). The diagenetic modifications affecting the crystal structure of clay minerals (both kaolin-group and illitic minerals) were studied using X-ray diffraction (XRD). The XRD study includes oriented and random mounts of various size fractions, numerical processing (decomposition) of XRD profiles, and simulation of one-dimensional and three-dimensional XRD patterns. Petrographic observations, differential thermal analysis, K/Ar geochronology, and geochemical considerations complement the XRD study and allow determination of the sequence of mineral crystallization and the morphological evolution of clay minerals and place further constraints on the absolute timing of diagenetic events and on the nature of the fluids responsible for clay-mineral crystallization.

  7. Quantum photonics hybrid integration platform

    SciTech Connect (OSTI)

    Murray, E.; Floether, F. F.; Ellis, D. J. P.; Meany, T.; Bennett, A. J. Shields, A. J.; Lee, J. P.; Griffiths, J. P.; Jones, G. A. C.; Farrer, I.; Ritchie, D. A.

    2015-10-26

    Fundamental to integrated photonic quantum computing is an on-chip method for routing and modulating quantum light emission. We demonstrate a hybrid integration platform consisting of arbitrarily designed waveguide circuits and single-photon sources. InAs quantum dots (QD) embedded in GaAs are bonded to a SiON waveguide chip such that the QD emission is coupled to the waveguide mode. The waveguides are SiON core embedded in a SiO{sub 2} cladding. A tuneable Mach Zehnder interferometer (MZI) modulates the emission between two output ports and can act as a path-encoded qubit preparation device. The single-photon nature of the emission was verified using the on-chip MZI as a beamsplitter in a Hanbury Brown and Twiss measurement.

  8. NREL Develops ZnSiP2 for Silicon-Based Tandem Solar Cells (Fact Sheet), NREL Highlights in Research & Development, NREL (National Renewable Energy Laboratory)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Combining an Earth-abundant chalcopyrite with a silicon layer could significantly boost conversion efficiency above that of single-junction silicon solar cells. A current technological challenge in photovoltaics (PV) is to implement a lattice-matched, optically efficient material to be used in conjunction with silicon for tandem PV cells. III-V materials currently hold the world-record conver- sion efficiencies for both single- and multijunction cells. Researchers at the National Renewable

  9. OSTIblog Articles in the Bayesian Inference Topic | OSTI, US Dept of Energy

    Office of Scientific and Technical Information (OSTI)

    Office of Scientific and Technical Information Bayesian Inference Topic The Reverend Thomas Bayes by Kathy Chambers 06 Nov, 2013 in Products and Content 13432 bayesPicture.jpg The Reverend Thomas Bayes Read more about 13432 During the 1700's, the Reverend Thomas Bayes was a nonconformist minister at the Mount Sion Chapel in Tunbridge Wells, UK, about 40 miles southeast of central London. Having studied both theology and logic at the University of Edinburgh, he was also a mathematician and

  10. LANSCE Focus

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Focus Nuclear science observations and opportunities at the Los Alamos Neutron Science Center Colleagues, This special Focus issue highlights a set of nuclear physics capabilities at the Los Alamos Neutron Science Center (LANSCE) serving Los Alamos National Laboratory's national security mis- sion and the global scientific user community. With a total of 10 flight paths, LANSCE pro- vides the opportunity to perform experiments with low- to high-energy neutron sources and high-energy proton

  11. A low-power pressure-and temperature-programmed separation system for a micro gas chromatograph.

    SciTech Connect (OSTI)

    Sacks, Richard D. (University of Michigan, Ann Arbor, MI); Robinson, Alex Lockwood (Advanced Sensor Technologies, Albuquerque, NM); Lambertus, Gordon R. (University of Michigan, Ann Arbor, MI); Potkay, Joseph A. (University of Michigan, Ann Arbor, MI); Wise, Kensall D. (University of Michigan, Ann Arbor, MI)

    2006-10-01

    This thesis presents the theory, design, fabrication and testing of the microvalves and columns necessary in a pressure- and temperature-programmed micro gas chromatograph ({micro}GC). Two microcolumn designs are investigated: a bonded Si-glass column having a rectangular cross section and a vapor-deposited silicon oxynitride (Sion) column having a roughly circular cross section. Both microcolumns contain integrated heaters and sensors for rapid, controlled heating. The 3.2 cm x 3.2 cm, 3 m-long silicon-glass column, coated with a non-polar polydimethylsiloxane (PDMS) stationary phase, separates 30 volatile organic compounds (VOCs) in less than 6 min. This is the most efficient micromachined column reported to date, producing greater than 4000 plates/m. The 2.7 mm x 1.4 mm Sion column eliminates the glass sealing plate and silicon substrate using deposited dielectrics and is the lowest power and fastest GC column reported to date; it requires only 11 mW to raise the column temperature by 100 C and has a response time of 11s and natural temperature ramp rate of 580 C/min. A 1 m-long PDMS-coated Sion microcolumn separates 10 VOCs in 52s. A system-based design approach was used for both columns.

  12. Document

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    29 CFR Ch. XIV (7-1-04 Edition) § 1614.101 1614.402 Time for appeals to the Commis- sion. 1614.403 How to appeal. 1614.404 Appellate procedure. 1614.405 Decisions on appeals. 1614.406 Time limits. [Reserved] 1614.407 Civil action: Title VII, Age Dis- crimination in Employment Act and Re- habilitation Act. 1614.408 Civil action: Equal Pay Act. 1614.409 Effect of filing a civil action. Subpart E-Remedies and Enforcement 1614.501 Remedies and relief. 1614.502 Compliance with final Commission

  13. Document

    National Nuclear Security Administration (NNSA)

    66 29 CFR Ch. XIV (7-1-04 Edition) § 1614.101 1614.402 Time for appeals to the Commis- sion. 1614.403 How to appeal. 1614.404 Appellate procedure. 1614.405 Decisions on appeals. 1614.406 Time limits. [Reserved] 1614.407 Civil action: Title VII, Age Dis- crimination in Employment Act and Re- habilitation Act. 1614.408 Civil action: Equal Pay Act. 1614.409 Effect of filing a civil action. Subpart E-Remedies and Enforcement 1614.501 Remedies and relief. 1614.502 Compliance with final Commission

  14. Fusion Science to Prepare

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    DIII-D Explorations of Fusion Science to Prepare for ITER and FNSF Dr. Richard Buttery General Atomics Tuesday, Dec 10, 2013 - 11:00AM MBG AUDITORIUM Refreshments at 10:45AM The PrinceTon Plasma Physics laboraTory is a U.s. DeParTmenT of energy faciliTy Recent DIII-D research has provided significant new in- formation for the physics basis of key scientific issues for successful operation of ITER and future steady state fu- sion tokamaks, including control of edge localized modes (ELMs), plasma

  15. S A V A N N A H R I V E R S I T E

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Excerpts from "Strengthening Energy Security through Federal Partnerships" 67 ENE RGY The Military Engineer * No. 676 The need to shrink depen dence on fos- sil fuels is not a new conce pt in the na- tion's energy discus sion, nor is the need to invest in clean, renew able energy . But the challe nge of how to deliver solar, bioma ss, wind, wave, geothe rmal and other power genera tion techno logies in a cost effecti ve, large-s cale mann er-an d meet the chang - ing energy deman ds of

  16. OSTIblog Articles in the Thomas Bayes Topic | OSTI, US Dept of Energy

    Office of Scientific and Technical Information (OSTI)

    Office of Scientific and Technical Information Bayes Topic The Reverend Thomas Bayes by Kathy Chambers 06 Nov, 2013 in Products and Content 13432 bayesPicture.jpg The Reverend Thomas Bayes Read more about 13432 During the 1700's, the Reverend Thomas Bayes was a nonconformist minister at the Mount Sion Chapel in Tunbridge Wells, UK, about 40 miles southeast of central London. Having studied both theology and logic at the University of Edinburgh, he was also a mathematician and developed a

  17. OSTI, US Dept of Energy Office of Scientific and Technical Information |

    Office of Scientific and Technical Information (OSTI)

    Speeding access to science information from DOE and Beyond The Reverend Thomas Bayes by Kathy Chambers on Wed, November 06, 2013 13432 bayesPicture.jpg The Reverend Thomas Bayes Read more about 13432 During the 1700's, the Reverend Thomas Bayes was a nonconformist minister at the Mount Sion Chapel in Tunbridge Wells, UK, about 40 miles southeast of central London. Having studied both theology and logic at the University of Edinburgh, he was also a mathematician and developed a strong

  18. untitled

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    UNIVERSITY OF CALIFORNIA ileRL 919 cy 2 TWO-WEEK LOAN COpy This is a Library Circulating Copy which may be borrowed for two weeks. For a personal retention copy, call Tech. Info. Diu/sion, Ext. 5545 BERKELEY, CALIFORNIA '~ .:. .. -\ * UCRL-9l9 Unclassified Distribution UNIVERSITY OF CALIFORNIA Radiation Laboratory Contract No. W-7405-eng-48 A Thick Target for Synchrotrons and Betatrons E. M. McMillan September 19, 1950 Berkeley, California Unclassified Distribution ~2- USAF, USAF, USAF, USAF s

  19. L I NATIONAL' LEAD COMPANY OF OHIO

    Office of Legacy Management (LM)

    L I NATIONAL' LEAD COMPANY OF OHIO tJw HEALTH AND SAFETY DI"ISION - ANALITICIL DEPT. ANALYTICAL DATA SHEET _I . . NATIONAL LEAD COMPANY O F OHIO HEALTH AND SAFETY DIY1SION - ANALYTICAL DEPT. ANALYTICAL DATA SHEET NATIONA-i LEn' D COMPANY OF OHIO HEALTH AND SAFETY Dl"lSlDN - m4ALITICAL DEPT. ANALYTICAL DATA SHEET NO. I DlSTRlBUTlON OF COPIES I I A,w,lytlc.al Loboratorr (RBCORD COPI) 2 Induswlol Hvalen. B Rodhtlon Dept. 3 1 Water Trsotmmt Plant c=.z w&w hnp,., Only, - . _. NATIONAL

  20. Quality Assurance for Critical Decision Reviews RM

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Quality Assurance for Critical Decision Reviews Module March 2010 CD-0 O 0 OFFICE OF Q C CD-1 F ENVIRO Standard R Quality A Rev Critical Decis CD-2 M ONMENTAL Review Plan Assuranc view Module sion (CD) Ap CD March 2010 L MANAGE n (SRP) e (QA) e pplicability D-3 EMENT CD-4 Post Ope eration Standard Review Plan, 2 nd Edition, March 2010 i FOREWORD The Standard Review Plan (SRP) 1 provides a consistent, predictable corporate review framework to ensure that issues and risks that could challenge the

  1. Lithium-Sulfur Batteries: Development of High Energy Lithium-Sulfur Cells for Electric Vehicle Applications

    SciTech Connect (OSTI)

    2010-10-01

    BEEST Project: Sion Power is developing a lithium-sulfur (Li-S) battery, a potentially cost-effective alternative to the Li-Ion battery that could store 400% more energy per pound. All batteries have 3 key partsa positive and negative electrode and an electrolytethat exchange ions to store and release electricity. Using different materials for these components changes a batterys chemistry and its ability to power a vehicle. Traditional Li-S batteries experience adverse reactions between the electrolyte and lithium-based negative electrode that ultimately limit the battery to less than 50 charge cycles. Sion Power will sandwich the lithium- and sulfur-based electrode films around a separator that protects the negative electrode and increases the number of charges the battery can complete in its lifetime. The design could eventually allow for a battery with 400% greater storage capacity per pound than Li-Ion batteries and the ability to complete more than 500 recharge cycles.

  2. Assessment of Summer 1997 Motor Gasoline Price Increase

    Reports and Publications (EIA)

    1998-01-01

    Assesses the 1997 late summer gasoline market and some of the important issues surrounding that event.

  3. Sandwiched Rnyi divergence satisfies data processing inequality

    SciTech Connect (OSTI)

    Beigi, Salman [School of Mathematics, Institute for Research in Fundamental Sciences (IPM), P.O. Box 19395-5746, Tehran (Iran, Islamic Republic of)] [School of Mathematics, Institute for Research in Fundamental Sciences (IPM), P.O. Box 19395-5746, Tehran (Iran, Islamic Republic of)

    2013-12-15

    Sandwiched (quantum) ?-Rnyi divergence has been recently defined in the independent works of Wilde et al. [Strong converse for the classical capacity of entanglement-breaking channels, preprint http://arxiv.org/abs/arXiv:1306.1586 (2013)] and Mller-Lennert et al. [On quantum Rnyi entropies: a new definition, some properties and several conjectures, preprint http://arxiv.org/abs/arXiv:1306.3142v1 (2013)]. This new quantum divergence has already found applications in quantum information theory. Here we further investigate properties of this new quantum divergence. In particular, we show that sandwiched ?-Rnyi divergence satisfies the data processing inequality for all values of ? > 1. Moreover we prove that ?-Holevo information, a variant of Holevo information defined in terms of sandwiched ?-Rnyi divergence, is super-additive. Our results are based on Hlder's inequality, the Riesz-Thorin theorem and ideas from the theory of complex interpolation. We also employ Sion's minimax theorem.

  4. Utilizing Semantic Big Data for realizing a National-scale Infrastructure Vulnerability Analysis System

    SciTech Connect (OSTI)

    Chinthavali, Supriya; Shankar, Mallikarjun

    2016-01-01

    Critical Infrastructure systems(CIs) such as energy, water, transportation and communication are highly interconnected and mutually dependent in complex ways. Robust modeling of CIs interconnections is crucial to identify vulnerabilities in the CIs. We present here a national-scale Infrastructure Vulnerability Analysis System (IVAS) vision leveraging Se- mantic Big Data (SBD) tools, Big Data, and Geographical Information Systems (GIS) tools. We survey existing ap- proaches on vulnerability analysis of critical infrastructures and discuss relevant systems and tools aligned with our vi- sion. Next, we present a generic system architecture and discuss challenges including: (1) Constructing and manag- ing a CI network-of-networks graph, (2) Performing analytic operations at scale, and (3) Interactive visualization of ana- lytic output to generate meaningful insights. We argue that this architecture acts as a baseline to realize a national-scale network based vulnerability analysis system.

  5. FIlea

    Office of Legacy Management (LM)

    FIlea THRU: R. L. Kirk and 3. N. ?%l.mxe Hr. Brandgun of Health CC Safety ?M.sion and the wrfte~! tisited -de onJamwy 8,19% to lnvastl@ethe aause of tbs fire In aSJlvenio sarap nhipmnttoHWat St. Lauis. The per&x13 ccmtactod vere I-I. Grleb, W. J. Danahue, and A. A. cannon of Sylv@a. On DeoemSar 23, 1953, Sylvnnla, S-de, supped 809 &i. of uranium acrap,wtich vas identlfled on SF 1Ol Fona 110. 4 - SYL tg MX 83 urcminmbar and&de scrap. I On Saturday, hxnh~r 26, 1953, MIX vaa notified tv

  6. Regional Dialogue Template

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    day is a Saturday, Sunday, or federal holiday, the difference shall be paid by the next business day. (c) Late Payments After the Due Date, a late payment charge equal to the...

  7. FY 2015 | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Due Tuesday, October 14, 2014 11:59pm ET Tuesday, February 03, 2015 11:59pm ET Award Notification Early January 2015* Late April 2015* Grant Start Date Late February 2015* Early ...

  8. Application for presidential permit OE Docket No. PP-230-4 International

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Transmission Company: Response to Late Motion to Intervene from FirstEnergy Service Corporation | Department of Energy Response to Late Motion to Intervene from FirstEnergy Service Corporation Application for presidential permit OE Docket No. PP-230-4 International Transmission Company: Response to Late Motion to Intervene from FirstEnergy Service Corporation Response from International Transmission Company to late motion to intervene from FirstEnergy Service Corporation in the matter of the

  9. Results from tests of DuPont crossflow filter

    SciTech Connect (OSTI)

    Steimke, J.L.

    2000-05-05

    Crossflow filtration will be used to filter radioactive waste slurry as part of the Late Wash Process.

  10. Application for presidential permit OE Docket No. PP-230-4 International

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Transmission Company: Response to Late Motion to Intervene and Comments | Department of Energy and Comments Application for presidential permit OE Docket No. PP-230-4 International Transmission Company: Response to Late Motion to Intervene and Comments Answer of International Transmission Company to late motions to intervene and comments of Baltimore Gas and Electric Company, American Electric Power, and Pepco Holdings, Inc. PP-230-4 International Transmission Company (1.11 MB) More

  11. Application for presidential permit OE Docket No. PP-230-4 International

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Transmission Company: Response to Late Motion to Intervene from PJM Interconnection LLC | Department of Energy from PJM Interconnection LLC Application for presidential permit OE Docket No. PP-230-4 International Transmission Company: Response to Late Motion to Intervene from PJM Interconnection LLC Response from International Transmission Company to late motion to intervene from PJM Interconnection in the matter of the application for a presidential permit authorizing International

  12. Application for presidential permit OE Docket No. PP-230-4 International

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Transmission Company: Response to Late Motion to Intervene of New York Transmission Owners | Department of Energy Late Motion to Intervene of New York Transmission Owners Application for presidential permit OE Docket No. PP-230-4 International Transmission Company: Response to Late Motion to Intervene of New York Transmission Owners Application from International Transmission Company to construct, operate, and maintain electric transmission facilities at the U.S. - Canada Border. Response to

  13. Microsoft Word - SPEAR3 Jul-Sep 02 Qtrly Rpt.doc

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Magnet System - A significant milestone was achieved late April with the final shipment of 20 corrector magnets from the Institute of High Energy Physics (IHEP) in Beijing. This ...

  14. OSTIblog Articles in the Thomas Bayes Topic | OSTI, US Dept of...

    Office of Scientific and Technical Information (OSTI)

    he was also a mathematician and developed a strong interest in probability late in life. ... After his death, a good friend... Related Topics: Bayesian Inference, Oak Ridge National ...

  15. OSTIblog Articles in the Bayesian Inference Topic | OSTI, US...

    Office of Scientific and Technical Information (OSTI)

    he was also a mathematician and developed a strong interest in probability late in life. ... After his death, a good friend... Related Topics: Bayesian Inference, Oak Ridge National ...

  16. Slide 1

    Broader source: Energy.gov (indexed) [DOE]

    Late payment fee assessed, which typically is higher than the prompt payment interest. Frauddelinquency losses borne by the bank Comparison of Charge Card FeesLiabilities Office...

  17. QER- Comment of Solar Electric Power Association

    Broader source: Energy.gov [DOE]

    I realize the deadline has passed, but attached is a document for inclusion in the Virtual Library if it's not too late. Best regards,

  18. Indonesia-Bank Danamon DCA Guarantee | Open Energy Information

    Open Energy Info (EERE)

    officials and contractor staff in late 2008, each evaluation and the meta-evaluation synthesis are intended to provide EGATDC with information to (1) demonstrate and communicate...

  19. Office of Energy Efficiency & Renewable Energy | Department of...

    Energy Savers [EERE]

    ... More Videos Clean Energy on Twitter Aug. 31, 2016 Lots of exciting water power news lately Announcing 20M for wave & tidal energy research: http:energy.goveerearticles...

  20. NCAI Mid-Year Conference and Marketplace

    Broader source: Energy.gov [DOE]

    The National Congress of American Indians (NCAI) is hosting its mid-year conference in late June. The conference will feature breakout sessions and committee meetings.

  1. NGEN Partners LLC (Silicon Valley) | Open Energy Information

    Open Energy Info (EERE)

    University Avenue Place: Palo Alto, California Zip: 94301 Region: Bay Area Product: Invest in early to late-stage clean energy businesses. Year Founded: 2001 Phone Number: (650)...

  2. Rev. Martin Luther King, Jr. Commemorative Program

    Broader source: Energy.gov [DOE]

    All employees are invited to the Department’s 2014 Commemorative Program honoring the late Rev. Dr. Martin Luther King, Jr. on January 22, 2014 at 11 am.

  3. PPPO News Archive | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    site have been delivered to an offsite disposal facility. August 27, 2013 Waste management and transportation personnel worked late to complete the first shipment to WCS....

  4. Natural Gas Weekly Update

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    March 12, 2009 Overview Prices Storage Other Market Trends Natural Gas Transportation Update Overview (For the Week Ending Wednesday, March 4, 2009) A late winter cold spell in...

  5. Slide 1

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    grown at 3% CAGR since late 1970s Source: University of Minnesota Institute on the Environment; Brazilian Sugarcane Industry Association (UNICA), Food and Agricultural ...

  6. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    ... the late phase, with different values of shock revival time as a parameter that should ... basic results, including the dependence on progenitor models and the shock revival time. ...

  7. Workbook Contents

    U.S. Energy Information Administration (EIA) Indexed Site

    Washington Natural Gas Exports (Dollars per Thousand Cubic Feet)" ,"Click worksheet name or tab at bottom for data" ,"Worksheet Name","Description"," Of Series","Frequency","Lates...

  8. Morocco

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    MAURITANIA) SUMMARY In addition to large accumulations of Late-Cretaceous immature oil shale (kerogen) at depths suitable for surface mining 1 , Morocco and its two neighboring...

  9. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    ... Repository Development (United States) Research Org: Sponsoring ... (3) computer codes (2) death (2) fluorine 18 (2) ... The 7.4% rate of grade 3 late toxicity was comparable ...

  10. I

    Office of Scientific and Technical Information (OSTI)

    ... During the late 1970s, breeder reactors using mixed ... 1000 MW(e) liquid-metal fast breeder reac- tors (LMFBR). ... versus standardized sodium hydroxide using multiple ...