National Library of Energy BETA

Sample records for labeling programs low-flow

  1. Energy-efficient appliance labeling in China: Lessons for successful labeling programs in varied markets

    SciTech Connect (OSTI)

    Lin, Jiang; Townend, Jeanne; Fridley, David; McNeil, Gary; Silva, Tony; Clark, Robin

    2002-08-20

    Appliance ownership and production has increased dramatically in China in the past two decades. From extremely low levels in 1980, China's appliance industry has become one of the largest in the world, with sales topping U.S. $14.4 billion in 2000. In 1981, less than 1 percent of urban Chinese households owned a refrigerator; by 1998, that number had increased to over 75 percent. This dramatic increase in sales and ownership leads to an excellent opportunity to impact energy consumption in China by affecting the energy efficiency of appliances being bought and sold. In general, Chinese consumers value energy efficiency and are knowledgeable about the operating costs of major appliances. However, the Chinese marketplace does not provide information that consumers trust about the energy consumption of specific products. Thus, several interdependent organizations have emerged in China to provide information and market supports for energy efficiency. This paper describes the appliance market in China and the evolution of its standards and labeling programs and the agencies that implement them. It discusses the authors' work with these organizations in developing energy efficiency criteria and supporting an energy efficiency endorsement labeling program in China. It describes how the authors have used their experience with ENERGY STAR{reg_sign} and other programs in the U.S. to work with China to develop a successful program specific to Chinese conditions, with a particular emphasis on refrigerators. It then gives the author's market assessment of the Chinese refrigerator market and recommendations for a successful labeling program and transferable lessons for developing energy efficiency labeling programs in varied markets. This paper is based on the authors' market research, their support in setting energy efficiency criteria in China, interviews with Chinese manufacturers, retailers, and sales staff, and the development and implementation of labeling strategies and

  2. Calendar Year 2008 Program Benefits for ENERGY STAR Labeled Products

    SciTech Connect (OSTI)

    Homan, GregoryK; Sanchez, Marla; Brown, RichardE; Lai, Judy

    2010-08-24

    This paper presents current and projected savings for ENERGY STAR labeled products, and details the status of the model as implemented in the September 2009 spreadsheets. ENERGY STAR is a voluntary energy efficiency labeling program operated jointly by the Environmental Protection Agency (US EPA) and the U.S. Department of Energy (US DOE), designed to identify and promote energy-efficient products, buildings and practices. Since the program inception in 1992, ENERGY STAR has become a leading international brand for energy efficient products, and currently labels more than thirty products, spanning office equipment, heating, cooling and ventilation equipment, commercial and residential lighting, home electronics, and major appliances. ENERGY STAR's central role in the development of regional, national and international energy programs necessitates an open process whereby its program achievements to date as well as projected future savings are shared with stakeholders. This report presents savings estimates for ENERGY STAR labeled products. We present estimates of energy, dollar, and carbon savings achieved by the program in the year 2008, annual forecasts for 2009 and 2010, and cumulative savings estimates for the period 1993 through 2008 and cumulative forecasts for the period 2009 through 2015. Through 2008 the program saved 8.8 Quads of primary energy and avoided the equivalent of 158 metric tones carbon (MtC). The forecast for the period 2009-2015 is 18.1 Quads or primary energy saved and 316 MtC emissions avoided. The sensitivity analysis bounds the best estimate of carbon avoided between 104 MtC and 213 MtC (1993 to 2008) and between 206 MtC and 444 MtC (2009 to 2015). In this report we address the following questions for ENERGY STAR labeled products: (1) How are ENERGY STAR impacts quantified; (2) What are the ENERGY STAR achievements; and (3) What are the limitations to our method?

  3. Calendar Year 2009 Program Benefits for ENERGY STAR Labeled Products

    SciTech Connect (OSTI)

    Homan, Gregory K; Sanchez, Marla C.; Brown, Richard E.

    2010-11-15

    ENERGY STAR is a voluntary energy efficiency labeling program operated jointly by the Environmental Protection Agency (US EPA) and the U.S. Department of Energy (US DOE), designed to identify and promote energy-efficient products, buildings and practices. Since the program inception in 1992, ENERGY STAR has become a leading international brand for energy efficient products, and currently labels more than thirty products, spanning office equipment, heating, cooling and ventilation equipment, commercial and residential lighting, home electronics, and major appliances. ENERGY STAR's central role in the development of regional, national and international energy programs necessitates an open process whereby its program achievements to date as well as projected future savings are shared with stakeholders. This report presents savings estimates from the use ENERGY STAR labeled products. We present estimates of energy, dollar, and carbon savings achieved by the program in the year 2009, annual forecasts for 2010 and 2011, and cumulative savings estimates for the period 1993 through 2009 and cumulative forecasts for the period 2010 through 2015. Through 2009 the program saved 9.5 Quads of primary energy and avoided the equivalent of 170 million metric tons carbon (MMTC). The forecast for the period 2009-2015 is 11.5 Quads or primary energy saved and 202 MMTC emissions avoided. The sensitivity analysis bounds the best estimate of carbon avoided between 110 MMTC and 231 MMTC (1993 to 2009) and between 130 MMTC and 285 MMTC (2010 to 2015).

  4. Calendar Year 2007 Program Benefits for ENERGY STAR Labeled Products

    SciTech Connect (OSTI)

    Sanchez, Marla Christine; Homan, Gregory; Brown, Richard

    2008-10-31

    ENERGY STAR is a voluntary energy efficiency-labeling program operated jointly by the United States Department of Energy and the United States Environmental Protection Agency (US EPA). Since the program inception in 1992, ENERGY STAR has become a leading international brand for energy efficient products. ENERGY STAR's central role in the development of regional, national, and international energy programs necessitates an open process whereby its program achievements to date as well as projected future savings are shared with committed stakeholders. Through 2007, the program saved 7.1 Quads of primary energy and avoided 128 MtC equivalent. The forecast shows that the program is expected to save 21.2 Quads of primary energy and avoid 375 MtC equivalent over the period 2008-2015. The sensitivity analysis bounds the best estimate of carbon avoided between 84 MtC and 172 MtC (1993 to 2007) and between 243 MtC and 519 MtC (2008 to 2015).

  5. International Experience in Standards and Labeling Programs for Rice Cookers

    SciTech Connect (OSTI)

    Zhou, Nan; Zheng, Nina

    2008-05-01

    China has had an active program on energy efficiency standards for household appliances since the mid-1990s. Rice cooker is among the first to be subject to such mandatory regulation, since it is one of the most prevalent electric appliances in Chinese households. Since first introduced in 1989, the minimum energy efficiency standard for rice cookers has not been revised. Therefore, the potential for energy saving is considerable. Initial analysis from CNIS indicates that potential carbon savings is likely to reach 7.6 million tons of CO2 by the 10th year of the standard implementation. Since September 2007, CNIS has been working with various groups to develop the new standard for rice cookers. With The Energy Foundation's support, LBNL has assisted CNIS in the revision of the minimum energy efficiency standard for rice cookers that is expected to be effective in 2009. Specifically, work has been in the following areas: assistance in developing consumer survey on usage pattern of rice cookers, review of international standards, review of international test procedures, comparison of the international standards and test procedures, and assessment of technical options of reducing energy use. This report particularly summarizes the findings of reviewing international standards and technical options of reducing energy consumption. The report consists of an overview of rice cooker standards and labeling programs and testing procedures in Hong Kong, South Korea, Japan and Thailand, and Japan's case study in developing energy efficiency rice cooker technologies and rice cooker efficiency programs. The results from the analysis can be summarized as the follows: Hong Kong has a Voluntary Energy Efficiency Labeling scheme for electric rice cookers initiated in 2001, with revision implemented in 2007; South Korea has both MEPS and Mandatory Energy Efficiency Label targeting the same category of rice cookers as Hong Kong; Thailand's voluntary endorsement labeling program is

  6. Global Potential of Energy Efficiency Standards and Labeling Programs

    SciTech Connect (OSTI)

    McNeil, Michael A; McNeil, Michael A.; Letschert, Virginie; de la Rue du Can, Stephane

    2008-06-15

    This report estimates the global potential reductions in greenhouse gas emissions by 2030 for energy efficiency improvements associated with equipment (appliances, lighting, and HVAC) in buildings by means of energy efficiency standards and labels (EES&L). A consensus has emerged among the world's scientists and many corporate and political leaders regarding the need to address the threat of climate change through emissions mitigation and adaptation. A further consensus has emerged that a central component of these strategies must be focused around energy, which is the primary generator of greenhouse gas emissions. Two important questions result from this consensus: 'what kinds of policies encourage the appropriate transformation to energy efficiency' and 'how much impact can these policies have'? This report aims to contribute to the dialogue surrounding these issues by considering the potential impacts of a single policy type, applied on a global scale. The policy addressed in this report is Energy Efficient Standards and Labeling (EES&L) for energy-consuming equipment, which has now been implemented in over 60 countries. Mandatory energy performance standards are important because they contribute positively to a nation's economy and provide relative certainty about the outcome (both timing and magnitudes). Labels also contribute positively to a nation's economy and importantly increase the awareness of the energy-consuming public. Other policies not analyzed here (utility incentives, tax credits) are complimentary to standards and labels and also contribute in significant ways to reducing greenhouse gas emissions. We believe the analysis reported here to be the first systematic attempt to evaluate the potential of savings from EES&L for all countries and for such a large set of products. The goal of the analysis is to provide an assessment that is sufficiently well-quantified and accurate to allow comparison and integration with other strategies under

  7. Compliance and Verification of Standards and Labeling Programs in China: Lessons Learned

    SciTech Connect (OSTI)

    Saheb, Yamina; Zhou, Nan; Fridley, David; Pierrot, Andre

    2010-08-01

    After implementing several energy efficiency standards and labels (30 products covered by MEPS, 50 products covered by voluntary labels and 19 products by mandatory labels), the China National Institute of Standardization (CNIS) is now implementing verification and compliance mechanism to ensure that the energy information of labeled products comply with the requirements of their labels. CNIS is doing so by organizing check testing on a random basis for room air-conditioners, refrigerators, motors, heaters, computer displays, ovens, and self -ballasted lamps. The purpose of the check testing is to understand the implementation of the Chinese labeling scheme and help local authorities establishing effective compliance mechanisms. In addition, to ensure robustness and consistency of testing results, CNIS has coordinated a round robin testing for room air conditioners. Eight laboratories (Chinese (6), Australian (1) and Japanese (1)) have been involved in the round robin testing and tests were performed on four sets of samples selected from manufacturer's production line. This paper describes the methodology used in undertaking both check and round robin testing, provides analysis of testing results and reports on the findings. The analysis of both check and round robin testing demonstrated the benefits of a regularized verification and monitoring system for both laboratories and products such as (i) identifying the possible deviations between laboratories to correct them, (ii) improving the quality of testing facilities, (iii) ensuring the accuracy and reliability of energy label information in order to strength the social credibility of the labeling program and the enforcement mechanism in place.

  8. Compliance and Verification of Standards and Labelling Programs in China: Lessons Learned

    SciTech Connect (OSTI)

    Saheb, Yamina; Zhou, Nan; Fridley, David; Pierrot, André

    2010-06-11

    After implementing several energy efficiency standards and labels (30 products covered by MEPS, 50 products covered by voluntary labels and 19 products by mandatory labels), the China National Institute of Standardization (CNIS) is now implementing verification and compliance mechanism to ensure that the energy information of labeled products comply with the requirements of their labels. CNIS is doing so by organizing check testing on a random basis for room air-conditioners, refrigerators, motors, heaters, computer displays, ovens, and self -ballasted lamps. The purpose of the check testing is to understand the implementation of the Chinese labeling scheme and help local authorities establishing effective compliance mechanisms. In addition, to ensure robustness and consistency of testing results, CNIS has coordinated a round robin testing for room air conditioners. Eight laboratories (Chinese (6), Australian (1) and Japanese (1)) have been involved in the round robin testing and tests were performed on four sets of samples selected from manufacturer?s production line. This paper describes the methodology used in undertaking both check and round robin testing, provides analysis of testing results and reports on the findings. The analysis of both check and round robin testing demonstrated the benefits of a regularized verification and monitoring system for both laboratories and products such as (i) identifying the possible deviations between laboratories to correct them, (ii) improving the quality of testing facilities, (iii) ensuring the accuracy and reliability of energy label information in order to strength the social credibility of the labeling program and the enforcement mechanism in place.

  9. Feasibility of an appliance energy testing and labeling program for Sri Lanka

    SciTech Connect (OSTI)

    Biermayer, Peter; Busch, John; Hakim, Sajid; Turiel, Issac; du Pont, Peter; Stone, Chris

    2000-04-01

    A feasibility study evaluated the costs and benefits of establishing a program for testing, labeling and setting minimum efficiency standards for appliances and lighting in Sri Lanka. The feasibility study included: refrigerators, air-conditioners, flourescent lighting (ballasts & CFls), ceiling fans, motors, and televisions.

  10. International Review of the Development and Implementation of Energy Efficiency Standards and Labeling Programs

    SciTech Connect (OSTI)

    Zhou, Nan; Zheng, Nina; Fridley, David

    2012-02-28

    Appliance energy efficiency standards and labeling (S&L) programs have been important policy tools for regulating the efficiency of energy-using products for over 40 years and continue to expand in terms of geographic and product coverage. The most common S&L programs include mandatory minimum energy performance standards (MEPS) that seek to push the market for efficient products, and energy information and endorsement labels that seek to pull the market. This study seeks to review and compare some of the earliest and most well-developed S&L programs in three countries and one region: the U.S. MEPS and ENERGY STAR, Australia MEPS and Energy Label, European Union MEPS and Ecodesign requirements and Energy Label and Japanese Top Runner programs. For each program, key elements of S&L programs are evaluated and comparative analyses across the programs undertaken to identify best practice examples of individual elements as well as cross-cutting factors for success and lessons learned in international S&L program development and implementation. The international review and comparative analysis identified several overarching themes and highlighted some common factors behind successful program elements. First, standard-setting and programmatic implementation can benefit significantly from a legal framework that stipulates a specific timeline or schedule for standard-setting and revision, product coverage and legal sanctions for non-compliance. Second, the different MEPS programs revealed similarities in targeting efficiency gains that are technically feasible and economically justified as the principle for choosing a standard level, in many cases at a level that no product on the current market could reach. Third, detailed survey data such as the U.S. Residential Energy Consumption Survey (RECS) and rigorous analyses provide a strong foundation for standard-setting while incorporating the participation of different groups of stakeholders further strengthen the process

  11. ISSUANCE 2016-06-10: Energy Conservation Program: Certification, Compliance, Labeling, and Enforcement for Electric Motors and Small Electric Motors, Notice of Proposed Rulemaking

    Broader source: Energy.gov [DOE]

    Energy Conservation Program: Certification, Compliance, Labeling, and Enforcement for Electric Motors and Small Electric Motors, Notice of Proposed Rulemaking

  12. Calendar Year 2007 Program Benefits for U.S. EPA Energy Star Labeled Products: Expanded Methodology

    SciTech Connect (OSTI)

    Sanchez, Marla; Homan, Gregory; Lai, Judy; Brown, Richard

    2009-09-24

    This report provides a top-level summary of national savings achieved by the Energy Star voluntary product labeling program. To best quantify and analyze savings for all products, we developed a bottom-up product-based model. Each Energy Star product type is characterized by product-specific inputs that result in a product savings estimate. Our results show that through 2007, U.S. EPA Energy Star labeled products saved 5.5 Quads of primary energy and avoided 100 MtC of emissions. Although Energy Star-labeled products encompass over forty product types, only five of those product types accounted for 65percent of all Energy Star carbon reductions achieved to date, including (listed in order of savings magnitude)monitors, printers, residential light fixtures, televisions, and furnaces. The forecast shows that U.S. EPA?s program is expected to save 12.2 Quads of primary energy and avoid 215 MtC of emissions over the period of 2008?2015.

  13. 2006 Status Report Savings Estimates for the ENERGY STAR(R)Voluntary Labeling Program

    SciTech Connect (OSTI)

    Webber, Carrie A.; Brown, Richard E.; Sanchez, Marla; Homan,Gregory K.

    2006-03-07

    ENERGY STAR(R) is a voluntary labeling program designed toidentify and promote energy-efficient products, buildings and practices.Operated jointly by the Environmental Protection Agency (EPA) and theU.S. Department of Energy (DOE), ENERGY STAR labels exist for more thanthirty products, spanning office equipment, residential heating andcooling equipment, commercial and residential lighting, home electronics,and major appliances. This report presents savings estimates for a subsetof ENERGY STAR labeled products. We present estimates of the energy,dollar and carbon savings achieved by the program in the year 2005, whatwe expect in 2006, and provide savings forecasts for two marketpenetration scenarios for the periods 2006 to 2015 and 2006 to 2025. Thetarget market penetration forecast represents our best estimate of futureENERGY STAR savings. It is based on realistic market penetration goalsfor each of the products. We also provide a forecast under the assumptionof 100 percent market penetration; that is, we assume that all purchasersbuy ENERGY STAR-compliant products instead of standard efficiencyproducts throughout the analysis period.

  14. Assessment of the Impacts of Standards and Labeling Programs inMexico (four products).

    SciTech Connect (OSTI)

    Sanchez, Itha; Pulido, Henry; McNeil, Michael A.; Turiel, Isaac; della Cava, Mirka

    2007-06-12

    This study analyzes impacts from energy efficiency standards and labeling in Mexico from 1994 through 2005 for four major products: household refrigerators, room air conditioners, three-phase (squirrel cage) induction motors, and clothes washers. It is a retrospective analysis, seeking to assess verified impacts on product efficiency in the Mexican market in the first ten years after standards were implemented. Such an analysis allows the Mexican government to compare actual to originally forecast program benefits. In addition, it provides an extremely valuable benchmark for other countries considering standards, and to the energy policy community as a whole. The methodology for evaluation begins with historical test data taken for a large number of models of each product type between 1994 and 2005. The pre-standard efficiency of models in 1994 is taken as a baseline throughout the analysis. Model efficiency data were provided by an independent certification laboratory (ANCE), which tested products as part of the certification and enforcement mechanism defined by the standards program. Using this data, together with economic and market data provided by both government and private sector sources, the analysis considers several types of national level program impacts. These include: Energy savings; Environmental (emissions) impacts, and Net financial impacts to consumers, manufacturers and utilities. Energy savings impacts are calculated using the same methodology as the original projections, allowing a comparison. Other impacts are calculated using a robust and sophisticated methodology developed by the Instituto de Investigaciones Electricas (IIE) and Lawrence Berkeley National Laboratory (LBNL), in a collaboration supported by the Collaborative Labeling and Standards Program (CLASP).

  15. Acting Globally: Potential Carbon Emissions Mitigation Impacts from an International Standards and Labelling Program

    SciTech Connect (OSTI)

    McNeil, Michael A; Letschert, Virginie E.; de la Rue du Can, Stephane; Egan, Christine

    2009-05-29

    This paper presents an analysis of the potential impacts of an international initiative designed to support and promote the development and implementation of appliances standards and labelling programs throughout the world. As part of previous research efforts, LBNL developed the Bottom Up Energy Analysis System (BUENAS), an analysis framework that estimates impact potentials of energy efficiency policies on a global scale. In this paper, we apply this framework to an initiative that would result in the successful implementation of programs focused on high priority regions and product types, thus evaluating the potential impacts of such an initiative in terms of electricity savings and carbon mitigation in 2030. In order to model the likely parameters of such a program, we limit impacts to a five year period starting in 2009, but assume that the first 5 years of a program will result in implementation of 'best practice' minimum efficiency performance standards by 2014. The 'high priority' regions considered are: Brazil, China, the European Union,India, Mexico and the United States. The products considered are: refrigerators, air conditioners, lighting (both fluorescent and incandescent), standby power (for consumer electronics) and televisions in the residential sector, and air conditioning and lighting in commercial buildings. In 2020, these regions and enduses account for about 37percent of global residential electricity and 29percent of electricity in commercial buildings. We find that 850Mt of CO2 could be saved in buildings by 2030 compared to the baseline forecast.

  16. ACL monitoring using a low-flow sampling technique: A case study

    SciTech Connect (OSTI)

    Hurley, D.F.; Whitehouse, J.M.

    1995-12-31

    A dedicated low-flow groundwater sample collection system was designed for implementation in a post-closure ACL monitoring program at the Yaworski Lagoon NPL site in Canterbury, Connecticut. The system includes dedicated bladder pumps with intake ports located in the screened interval of the monitoring wells. This sampling technique was implemented in the spring of 1993. The system was designed to simultaneously obtain samples directly from the screened interval of nested wells in three distinct water bearing zones. Sample collection is begun upon stabilization of field parameters. Other than line volume, no prior purging of the well is required. It was found that dedicated low-flow sampling from the screened interval provides a method of representative sample collection without the bias of suspended solids introduced by traditional techniques of pumping and bailing. Analytical data indicate that measured chemical constituents are representative of groundwater migrating through the screened interval. Upon implementation of the low-flow monitoring system, analytical results exhibited a decrease in concentrations of some organic compounds and metals. The system has also proven to be a cost effective alternative to pumping and bailing which generate large volumes of purge water requiring containment and disposal.

  17. Comparison of Test Procedures and Energy Efficiency Criteria in Selected International Standards and Labeling Programs for Clothes Washers, Water Dispensers, Vending Machines and CFLs

    SciTech Connect (OSTI)

    Fridley, David; Zheng, Nina; Zhou, Nan

    2010-06-01

    Since the late 1970s, energy labeling programs and mandatory energy performance standards have been used in many different countries to improve the efficiency levels of major residential and commercial equipment. As more countries and regions launch programs covering a greater range of products that are traded worldwide, greater attention has been given to harmonizing the specific efficiency criteria in these programs and the test methods for measurements. For example, an international compact fluorescent light (CFL) harmonization initiative was launched in 2006 to focus on collaboration between Australia, China, Europe and North America. Given the long history of standards and labeling programs, most major energy-consuming residential appliances and commercial equipment are already covered under minimum energy performance standards (MEPS) and/or energy labels. For these products, such as clothes washers and CFLs, harmonization may still be possible when national MEPS or labeling thresholds are revised. Greater opportunity for harmonization exists in newer energy-consuming products that are not commonly regulated but are under consideration for new standards and labeling programs. This may include commercial products such as water dispensers and vending machines, which are only covered by MEPS or energy labels in a few countries or regions. As China continues to expand its appliance standards and labeling programs and revise existing standards and labels, it is important to learn from recent international experiences with efficiency criteria and test procedures for the same products. Specifically, various types of standards and labeling programs already exist in North America, Europe and throughout Asia for products in China's 2010 standards and labeling programs, namely clothes washers, water dispensers, vending machines and CFLs. This report thus examines similarities and critical differences in energy efficiency values, test procedure specifications and other

  18. Savings estimates for the United States Environmental Protection Agency?s ENERGY STAR voluntary product labeling program

    SciTech Connect (OSTI)

    Sanchez, Marla Christine; Sanchez, Marla Christine; Brown, Richard; Homan, Gregory; Webber, Carrie

    2008-06-03

    ENERGY STAR is a voluntary energy efficiency-labeling program operated jointly by the United States Department of Energy and the United States Environmental Protection Agency (US EPA). Since the program inception in 1992, ENERGY STAR has become a leading international brand for energy efficient products. ENERGY STAR's central role in the development of regional, national, and international energy programs necessitates an open process whereby its program achievements to date as well as projected future savings are shared with committed stakeholders. Through 2006, US EPA?S ENERGY STAR labeled products saved 4.8 EJ of primary energy and avoided 82 Tg C equivalent. We project that US EPA?S ENERGY STAR labeled products will save 12.8 EJ and avoid 203 Tg C equivalent over the period 2007-2015. A sensitivity analysis examining two key inputs (carbon factor and ENERGY STAR unit sales) bounds the best estimate of carbon avoided between 54 Tg C and 107 Tg C (1993 to 2006) and between 132 Tg C and 278 Tg C (2007 to 2015).

  19. Microsoft Word - Smart Grid Certification and Labeling Program 09-11-2009 _3_.docx

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NETL Modern Grid Strategy Powering our 21st-Century Economy SMART GRID CERTIFICATION AND LABELING Conducted by National Energy Technology Laboratory for the U.S. Department of Energy Office of Electricity Delivery and Energy Reliability September 2009 Office of Electricity Delivery and Energy Reliability Smart Grid Certification and Labeling 1 DISCLAIMER This report was prepared as an account of work sponsored by an agency of the United States Government. Neither the United States Government nor

  20. Comparison of Test Procedures and Energy Efficiency Criteria in Selected International Standards & Labeling Programs for Copy Machines, External Power Supplies, LED Displays, Residential Gas Cooktops and Televisions

    SciTech Connect (OSTI)

    Zheng, Nina; Zhou, Nan; Fridley, David

    2012-03-01

    This report presents a technical review of international minimum energy performance standards (MEPS), voluntary and mandatory energy efficiency labels and test procedures for five products being considered for new or revised MEPS in China: copy machines, external power supply, LED displays, residential gas cooktops and flat-screen televisions. For each product, an overview of the scope of existing international standards and labeling programs, energy values and energy performance metrics and description and detailed summary table of criteria and procedures in major test standards are presented.

  1. OGE- Commercial Energy Efficiency Rebate Programs

    Broader source: Energy.gov [DOE]

    OGE Multi-family energy efficiency program provides installation of low cost energy saving products at no cost to the customer. The installation include: CFLs, low-flow shower heads, low flow...

  2. Installation of a Low Flow Unit at the Abiquiu Hydroelectric Facility

    SciTech Connect (OSTI)

    Jack Q. Richardson

    2012-06-28

    Final Technical Report for the Recovery Act Project for the Installation of a Low Flow Unit at the Abiquiu Hydroelectric Facility. The Abiquiu hydroelectric facility existed with two each 6.9 MW vertical flow Francis turbine-generators. This project installed a new 3.1 MW horizontal flow low flow turbine-generator. The total plant flow range to capture energy and generate power increased from between 250 and 1,300 cfs to between 75 and 1,550 cfs. Fifty full time equivalent (FTE) construction jobs were created for this project - 50% (or 25 FTE) were credited to ARRA funding due to the ARRA 50% project cost match. The Abiquiu facility has increased capacity, increased efficiency and provides for an improved aquatic environment owing to installed dissolved oxygen capabilities during traditional low flow periods in the Rio Chama. A new powerhouse addition was constructed to house the new turbine-generator equipment.

  3. Overview of Existing Home Energy Labels

    Office of Energy Efficiency and Renewable Energy (EERE)

    This analysis looks at home energy labeling programs around the world and highlights similarities and differences of various approaches.

  4. Navigation Labels and Approval

    Broader source: Energy.gov [DOE]

    EERE has commonly used and approved navigation labels. To maintain consistency in navigation across EERE, the EERE Template Coordinator reviews and approves requests for new navigation labels and...

  5. DOE Challenge Home Label Methodology | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Label Methodology DOE Challenge Home Label Methodology A document of the U.S. Department of Energy's Zero Energy Ready Home (formerly Challenge Home) program. ch_label_methodology_1012.pdf (222.71 KB) More Documents & Publications DOE Zero Energy Ready Home Partner Resources Indoor airPLUS Construction Specifications Indoor airPLUS Construction Specifications Version 1 (Rev. 02)

  6. CRAD, Equipment and Piping Labeling Assessment Plan | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Equipment and Piping Labeling Assessment Plan CRAD, Equipment and Piping Labeling Assessment Plan Performance Objective: To verify that facility equipment and piping are labeled in a manner such that facility personnel are able to positively identify equipment they operate. To ensure that an effective labeling program is in effect to reduce operator and maintenance errors from incorrect identification of equipment, to increase training effectiveness by tracing the actual facility system as

  7. DOE Challenge Home Label Methodology

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    October 2012 1 Label Methodology DOE Challenge Home Label Methodology October 2012 DOE Challenge Home October 2012 2 Label Methodology Contents Background ............................................................................................................................................... 3 Methodology ............................................................................................................................................. 5 Comfort/Quiet

  8. Laminated metal composite formed from low flow stress layers and high flow stress layers using flow constraining elements and making same

    DOE Patents [OSTI]

    Syn, C.K.; Lesuer, D.R.

    1995-07-04

    A laminated metal composite of low flow stress layers and high flow stress layers is described which is formed using flow constraining elements, preferably in the shape of rings, individually placed around each of the low flow stress layers while pressure is applied to the stack to bond the layers of the composite together, to thereby restrain the flow of the low flow stress layers from the stack during the bonding. The laminated metal composite of the invention is made by the steps of forming a stack of alternate layers of low flow stress layers and high flow stress layers with each layer of low flow stress material surrounded by an individual flow constraining element, such as a ring, and then applying pressure to the top and bottom surfaces of the resulting stack to bond the dissimilar layers together, for example, by compression rolling the stack. In a preferred embodiment, the individual flow constraining elements surrounding the layers of low flow stress material are formed of a material which may either be the same material as the material comprising the high flow stress layers, or have similar flow stress characteristics to the material comprising the high flow stress layers. Additional sacrificial layers may be added to the top and bottom of the stack to avoid damage to the stack during the bonding step; and these additional layers may then be removed after the bonding step. 5 figs.

  9. Laminated metal composite formed from low flow stress layers and high flow stress layers using flow constraining elements and making same

    DOE Patents [OSTI]

    Syn, Chol K.; Lesuer, Donald R.

    1995-01-01

    A laminated metal composite of low flow stress layers and high flow stress layers is described which is formed using flow constraining elements, preferably in the shape of rings, individually placed around each of the low flow stress layers while pressure is applied to the stack to bond the layers of the composite together, to thereby restrain the flow of the low flow stress layers from the stack during the bonding. The laminated metal composite of the invention is made by the steps of forming a stack of alternate layers of low flow stress layers and high flow stress layers with each layer of low flow stress material surrounded by an individual flow constraining element, such as a ring, and then applying pressure to the top and bottom surfaces of the resulting stack to bond the dissimilar layers together, for example, by compression rolling the stack. In a preferred embodiment, the individual flow constraining elements surrounding the layers of low flow stress material are formed of a material which may either be the same material as the material comprising the high flow stress layers, or have similar flow stress characteristics to the material comprising the high flow stress layers. Additional sacrificial layers may be added to the top and bottom of the stack to avoid damage to the stack during the bonding step; and these additional layers may then be removed after the bonding step.

  10. Low flow fume hood

    DOE Patents [OSTI]

    Bell, Geoffrey C.; Feustel, Helmut E.; Dickerhoff, Darryl J.

    2002-01-01

    A fume hood is provided having an adequate level of safety while reducing the amount of air exhausted from the hood. A displacement flow fume hood works on the principal of a displacement flow which displaces the volume currently present in the hood using a push-pull system. The displacement flow includes a plurality of air supplies which provide fresh air, preferably having laminar flow, to the fume hood. The displacement flow fume hood also includes an air exhaust which pulls air from the work chamber in a minimally turbulent manner. As the displacement flow produces a substantially consistent and minimally turbulent flow in the hood, inconsistent flow patterns associated with contaminant escape from the hood are minimized. The displacement flow fume hood largely reduces the need to exhaust large amounts of air from the hood. It has been shown that exhaust air flow reductions of up to 70% are possible without a decrease in the hood's containment performance. The fume hood also includes a number of structural adaptations which facilitate consistent and minimally turbulent flow within a fume hood.

  11. Capacitive label reader

    DOE Patents [OSTI]

    Arlowe, H. Duane

    1985-01-01

    A capacitive label reader includes an outer ring transmitting portion, an inner ring transmitting portion, and a plurality of insulated receiving portions. A label is the mirror-image of the reader except that identifying portions corresponding to the receiving portions are insulated from only one of two coupling elements. Positive and negative pulses applied, respectively, to the two transmitting rings biased a CMOS shift register positively to either a 1 or 0 condition. The output of the CMOS may be read as an indication of the label.

  12. Capacitive label reader

    DOE Patents [OSTI]

    Arlowe, H.D.

    1983-07-15

    A capacitive label reader includes an outer ring transmitting portion, an inner ring transmitting portion, and a plurality of insulated receiving portions. A label is the mirror-image of the reader except that identifying portions corresponding to the receiving portions are insulated from only one of two coupling elements. Positive and negative pulses applied, respectively, to the two transmitting rings biased a CMOS shift register positively to either a 1 or 0 condition. The output of the CMOS may be read as an indication of the label.

  13. Capacitive label reader

    DOE Patents [OSTI]

    Arlowe, H.D.

    1985-11-12

    A capacitive label reader includes an outer ring transmitting portion, an inner ring transmitting portion, and a plurality of insulated receiving portions. A label is the mirror-image of the reader except that identifying portions corresponding to the receiving portions are insulated from only one of two coupling elements. Positive and negative pulses applied, respectively, to the two transmitting rings biased a CMOS shift register positively to either a 1 or 0 condition. The output of the CMOS may be read as an indication of the label. 5 figs.

  14. Programming

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Programming Programming Compiling and linking programs on Euclid. Compiling Codes How to compile and link MPI codes on Euclid. Read More » Using the ACML Math Library How to compile and link a code with the ACML library and include the $ACML environment variable. Read More » Process Limits The hard and soft process limits are listed. Read More » Last edited: 2016-04-29 11:35:11

  15. Programming

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Programming Programming The genepool system has a diverse set of software development tools and a rich environment for delivering their functionality to users. Genepool has adopted a modular system which has been adapted from the Programming Environments similar to those provided on the Cray systems at NERSC. The Programming Environment is managed by a meta-module named similar to "PrgEnv-gnu/4.6". The "gnu" indicates that it is providing the GNU environment, principally GCC,

  16. Programming

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Read More Programming Tuning Options Tips for tuning performance on the Hopper system ... The ACML library is also supported on Hopper and Franklin. Read More PGAS Language ...

  17. Programming

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Storage & File Systems Application Performance Data & Analytics Job Logs & Statistics ... Each programming environment contains the full set of compatible compilers and libraries. ...

  18. Programming

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    using MPI and OpenMP on NERSC systems, the same does not always exist for other supported parallel programming models such as UPC or Chapel. At the same time, we know that these...

  19. Map labeling and its generalizations

    SciTech Connect (OSTI)

    Doddi, S. |; Marathe, M.V.; Mirzaian, A.; Moret, B.M.E.; Zhu, B. |

    1997-01-01

    Map labeling is of fundamental importance in cartography and geographical information systems and is one of the areas targeted for research by the ACM Computational Geometry Impact Task Force. Previous work on map labeling has focused on the problem of placing maximal uniform, axis-aligned, disjoint rectangles on the plane so that each point feature to be labeled lies at the corner of one rectangle. Here, we consider a number of variants of the map labeling problem. We obtain three general types of results. First, we devise constant-factor polynomial-time-approximation algorithms for labeling point features by rectangular labels, where the feature may lie anywhere on the boundary of its label region and where labeling rectangles may be placed in any orientation. These results generalize to the case of elliptical labels. Secondly, we consider the problem of labeling a map consisting of disjoint rectilinear fine segments. We obtain constant-factor polynomial-time approximation algorithms for the general problem and an optimal algorithm for the special case where all segments are horizontal. Finally, we formulate a bicriteria version of the map-labeling problem and provide bicriteria polynomial- time approximation schemes for a number of such problems.

  20. A high sensitivity fiber optic macro-bend based gas flow rate transducer for low flow rates: Theory, working principle, and static calibration

    SciTech Connect (OSTI)

    Schena, Emiliano; Saccomandi, Paola; Silvestri, Sergio

    2013-02-15

    A novel fiber optic macro-bend based gas flowmeter for low flow rates is presented. Theoretical analysis of the sensor working principle, design, and static calibration were performed. The measuring system consists of: an optical fiber, a light emitting diode (LED), a Quadrant position sensitive Detector (QD), and an analog electronic circuit for signal processing. The fiber tip undergoes a deflection in the flow, acting like a cantilever. The consequent displacement of light spot center is monitored by the QD generating four unbalanced photocurrents which are function of fiber tip position. The analog electronic circuit processes the photocurrents providing voltage signal proportional to light spot position. A circular target was placed on the fiber in order to increase the sensing surface. Sensor, tested in the measurement range up to 10 l min{sup -1}, shows a discrimination threshold of 2 l min{sup -1}, extremely low fluid dynamic resistance (0.17 Pa min l{sup -1}), and high sensitivity, also at low flow rates (i.e., 33 mV min l{sup -1} up to 4 l min{sup -1} and 98 mV min l{sup -1} from 4 l min{sup -1} up to 10 l min{sup -1}). Experimental results agree with the theoretical predictions. The high sensitivity, along with the reduced dimension and negligible pressure drop, makes the proposed transducer suitable for medical applications in neonatal ventilation.

  1. Labeled Cocaine Analogs

    DOE Patents [OSTI]

    Goodman, Mark M.; Shi, Bing Zhi; Keil, Robert N.

    1999-03-30

    Novel methods for positron emission tomography or single photon emission spectroscopy using tracer compounds having the structure: ##STR1## where X in .beta. configuration is phenyl, naphthyl; 2,3 or 4-iodophenyl; 2,3 or 4-(trimethylsilyl)phenyl; 3,4,5 or 6-iodonaphthyl; 3,4,5 or 6-(trimethylsilyl)naphthyl; 2,3 or 4-(trialkylstannyl)phenyl; or 3,4,5 or 6-(trialkylstannyl)napthyl Y in .beta. configuration is 2-fluoroethoxy, 3-fluoropropoxy, 4-fluorobutoxy, 2-fluorocyclopropoxy, 2 or 3-fluorocyclobutoxy, R,S 1'-fluoroisopropoxy, R 1'-fluoroisopropoxy, S 1'-fluoroisopropoxy, 1',3'-difluoroisopropoxy, R,S 1'-fluoroisobutoxy, R 1'-fluoroisobutoxy, S 1'-fluoroisobutoxy, R,S 4'-fluoroisobutoxy, R 4'-fluoroisobutoxy, S 4'-fluoroisobutoxy, or 1',1'-di(fluoromethyl)isobutoxy, The compounds bind dopamine transporter protein and can be labeled with .sup.18 F or .sup.123 I for imaging.

  2. Labeled Cocaine Analogs

    DOE Patents [OSTI]

    Goodman, Mark M.; Shi, Bing Zhi; Keil, Robert N.

    1999-01-26

    Novel compounds having the structure: ##STR1## where X in .beta. configuration is phenyl, naphthyl; 2,3 or 4-iodophenyl; 2,3 or 4-(trimethylsilyl)phenyl; 3,4,5 or 6-iodonaphthyl; 3,4,5 or 6-(trimethylsilyl)naphthyl; 2,3 or 4-(trialkylstannyl)phenyl; or 3,4,5 or 6-(trialkylstannyl)naphthyl Y in .beta. configuration is Y.sub.1 or Y.sub.2, where Y.sub.1 is 2-fluoroethoxy, 3-fluoropropoxy, 4-fluorobutoxy, 2-fluorocyclopropoxy, 2 or 3-fluorocyclobutoxy, R,S 1'-fluoroisopropoxy, R 1'-fluoroisopropoxy, S 1'-fluoroisopropoxy, 1',3'-difluoroisopropoxy, R,S 1'-fluoroisobutoxy, R 1'-fluoroisobutoxy, S 1'-fluoroisobutoxy, R,S 4'-fluoroisobutoxy, R 4'-fluoroisobutoxy, S 4'-fluoroisobutoxy, or 1',1'-di(fluoromethyl)isobutoxy, and Y.sub.2 is 2-methanesulfonyloxy ethoxy, 3-methanesulfonyloxy propoxy, 4-methanesulfonyloxy butoxy, 2-methanesulfonyloxy cyclopropoxy, 2 or 3-methanesulfonyloxy cyclobutoxy, 1'methanesulfonyloxy isopropoxy, 1'-fluoro, 3'-methanesulfonyloxy isopropoxy, 1'-methanesulfonyloxy, 3'-fluoro isopropoxy, 1'-methanesulfonyloxy isobutoxy, or 4'-methanesulfonyloxy isobutoxy bind dopamine transporter protein and can be labeled with .sup.18 F or .sup.123 I for imaging.

  3. Synthesis Of Labeled Metabolites

    DOE Patents [OSTI]

    Martinez, Rodolfo A.; Silks, III, Louis A.; Unkefer, Clifford J.; Atcher, Robert

    2004-03-23

    The present invention is directed to labeled compounds, for example, isotopically enriched mustard gas metabolites including: [1,1',2,2'-.sup.13 C.sub.4 ]ethane, 1,1'-sulfonylbis[2-(methylthio); [1,1',2,2'-.sup.13 C.sub.4 ]ethane, 1-[[2-(methylsulfinyl)ethyl]sulfonyl]-2-(methylthio); [1,1',2,2'-.sup.13 C.sub.4 ]ethane, 1,1'-sulfonylbis[2-(methylsulfinyl)]; and, 2,2'-sulfinylbis([1,2-.sup.13 C.sub.2 ]ethanol of the general formula ##STR1## where Q.sup.1 is selected from the group consisting of sulfide (--S--), sulfone (--S(O)--), sulfoxide (--S(O.sub.2)--) and oxide (--O--), at least one C* is .sup.13 C, X is selected from the group consisting of hydrogen and deuterium, and Z is selected from the group consisting of hydroxide (--OH), and --Q.sup.2 --R where Q.sup.2 is selected from the group consisting of sulfide (--S--), sulfone(--S(O)--), sulfoxide (--S(O.sub.2)--) and oxide (--O--), and R is selected from the group consisting of hydrogen, a C.sub.1 to C.sub.4 lower alkyl, and amino acid moieties, with the proviso that when Z is a hydroxide and Q.sup.1 is a sulfide, then at least one X is deuterium.

  4. Study on critical heat flux enhancement in flow boiling of SiC nano-fluids under low pressure and low flow conditions

    SciTech Connect (OSTI)

    Lee, S. W.; Park, S. D.; Kang, S.; Kim, S. M.; Seo, H.; Lee, D. W.; Bang, I. C.

    2012-07-01

    Critical heat flux (CHF) is the thermal limit of a phenomenon in which a phase change occurs during heating (such as bubbles forming on a metal surface used to heat water), which suddenly decreases the heat transfer efficiency, thus causing localized overheating of the heating surface. The enhancement of CHF can increase the safety margins and allow operation at higher heat fluxes; thus, it can increase the economy. A very interesting characteristics of nano-fluids is their ability to significantly enhance the CHF. nano-fluids are nano-technology-based colloidal dispersions engineered through stable suspending of nanoparticles. All experiments were performed in round tubes with an inner diameter of 0.01041 m and a length of 0.5 m under low pressure and low flow (LPLF) conditions at a fixed inlet temperature using water, 0.01 vol. % Al{sub 2}O{sub 3}/water and SiC/water nano-fluids. It was found that the CHF of the nano-fluids was enhanced and the CHF of the SiC/water nano-fluid was more enhanced than that of the Al{sub 2}O{sub 3}/water nano-fluid. (authors)

  5. OPS 9.18 Equipment and Piping Labeling 8/24/98 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    8 Equipment and Piping Labeling 8/24/98 OPS 9.18 Equipment and Piping Labeling 8/24/98 The objective of this surveillance is to verify that facility equipment and piping are labeled in a manner such that facility personnel are able to positively identify equipment they operate. This surveillance provides a basis for evaluating the effectiveness of the contractor's program for labeling equipment and piping and for establishing compliance with DOE requirements. OPS9-18.doc (31.5 KB) More Documents

  6. Department of Energy to Take Steps to Remove ENERGY STAR Label...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    As a result, effective January 2, 2010, certain LG French-door refrigerators are no longer eligible to carry the ENERGY STAR label. ENERGY STAR is a voluntary program sponsored ...

  7. Positron emitter labeled enzyme inhibitors

    DOE Patents [OSTI]

    Fowler, Joanna S.; MacGregor, Robert R.; Wolf, Alfred P.; Langstrom, Bengt

    1990-01-01

    This invention involves a new strategy for imaging and mapping enzyme activity in the living human and animal body using positron emitter-labeled suicide enzyme inactivators or inhibitors which become covalently bound to the enzyme as a result of enzymatic catalysis. Two such suicide inactivators for monoamine oxidase have been labeled with carbon-11 and used to map the enzyme subtypes in the living human and animal body using PET. By using positron emission tomography to image the distribution of radioactivity produced by the body penetrating radiation emitted by carbon-11, a map of functionally active monoamine oxidase activity is obtained. Clorgyline and L-deprenyl are suicide enzyme inhibitors and irreversibly inhibit monoamine oxidase. When these inhibitors are labeled with carbon-11 they provide selective probes for monoamine oxidase localization and reactivity in vivo using positron emission tomography.

  8. Positron emitter labeled enzyme inhibitors

    DOE Patents [OSTI]

    Fowler, J.S.; MacGregor, R.R.; Wolf, A.P.

    1987-05-22

    This invention involved a new strategy for imaging and mapping enzyme activity in the living human and animal body using positron emitter-labeled suicide enzyme inactivators or inhibitors which become covalently bound to the enzyme as a result of enzymatic catalysis. Two such suicide in activators for monoamine oxidase have been labeled with carbon-11 and used to map the enzyme subtypes in the living human and animal body using PET. By using positron emission tomography to image the distribution of radioactivity produced by the body penetrating radiation emitted by carbon-11, a map of functionally active monoamine oxidase activity is obtained. Clorgyline and L-deprenyl are suicide enzyme inhibitors and irreversibly inhibit monoamine oxidase. When these inhibitors are labeled with carbon-11 they provide selective probes for monoamine oxidase localization and reactivity in vivo using positron emission tomography. 2 figs.

  9. Development and Evaluation of an Externally Air-Cooled Low-Flow torch and the Attenuation of Space Charge and Matrix Effects in Inductively Coupled Plasma Mass Spectrometry

    SciTech Connect (OSTI)

    Praphairaksit, N.

    2000-09-12

    An externally air-cooled low-flow torch has been constructed and successfully demonstrated for applications in inductively coupled plasma mass spectrometry (ICP-MS). The torch is cooled by pressurized air flowing at {approximately}70 L/min through a quartz air jacket onto the exterior of the outer tube. The outer gas flow rate and operating RF forward power are reduced considerably. Although plasmas can be sustained at the operating power as low as 400 W with a 2 L/min of outer gas flow, somewhat higher power and outer gas flows are advisable. A stable and analytical useful plasma can be obtained at 850 W with an outer gas flow rate of {approximately}4 L/min. Under these conditions, the air-cooled plasma produces comparable sensitivities, doubly charged ion ratios, matrix effects and other analytical merits as those produced by a conventional torch while using significantly less argon and power requirements. Metal oxide ion ratios are slightly higher with the air-cooled plasma but can be mitigated by reducing the aerosol gas flow rate slightly with only minor sacrifice in analyte sensitivity. A methodology to alleviate the space charge and matrix effects in ICP-MS has been developed. A supplemental electron source adapted from a conventional electron impact ionizer is added to the base of the skimmer. Electrons supplied from this source downstream of the skimmer with suitable amount and energy can neutralize the positive ions in the beam extracted from the plasma and diminish the space charge repulsion between them. As a result, the overall ion transmission efficiency and consequent analyte ion sensitivities are significantly improved while other important analytical aspects, such as metal oxide ion ratio, doubly charged ion ratio and background ions remain relatively unchanged with the operation of this electron source. This technique not only improves the ion transmission efficiency but also minimizes the matrix effects drastically. The matrix-induced suppression

  10. Hemoglobin Labeled by Radioactive Lysine

    DOE R&D Accomplishments [OSTI]

    Bale, W. F.; Yuile, C. L.; DeLaVergne, L.; Miller, L. L.; Whipple, G. H.

    1949-12-08

    This paper reports on the utilization of tagged epsilon carbon of DL-lysine by a dog both anemic and hypoproteinemic due to repeated bleeding plus a diet low in protein. The experiment extended over period of 234 days, a time sufficient to indicate an erythrocyte life span of at least 115 days based upon the rate of replacement of labeled red cell proteins. The proteins of broken down red cells seem not to be used with any great preference for the synthesis of new hemoglobin.

  11. Alameda Municipal Power- Residential Energy Efficiency Rebate Program

    Broader source: Energy.gov [DOE]

    Alameda Municipal Power (AMP) is currently offering a refrigerator recycling program through which customers can purchase a refrigerator that has the "Energy Star" label (refrigerators smaller than...

  12. Energy-efficiency labels and standards: A guidebook for appliances, equipment and lighting

    SciTech Connect (OSTI)

    McMahon, James E.; Wiel, Stephen

    2001-02-16

    Energy-performance improvements in consumer products are an essential element in any government's portfolio of energy-efficiency and climate change mitigation programs. Governments need to develop balanced programs, both voluntary and regulatory, that remove cost-ineffective, energy-wasting products from the marketplace and stimulate the development of cost-effective, energy-efficient technology. Energy-efficiency labels and standards for appliances, equipment, and lighting products deserve to be among the first policy tools considered by a country's energy policy makers. The U.S. Agency for International Development (USAID) and the United Nations Foundation (UNF) recognize the need to support policy makers in their efforts to implement energy-efficiency standards and labeling programs and have developed this guidebook, together with the Collaborative Labeling and Appliance Standards Program (CLASP), as a primary reference. This guidebook was prepared over the course of the past year with significant contribution from the authors and reviewers mentioned previously. Their diligent participation has made this the international guidance tool it was intended to be. The lead authors would also like to thank the following individuals for their support in the development, production, and distribution of the guidebook: Marcy Beck, Elisa Derby, Diana Dhunke, Ted Gartner, and Julie Osborn of Lawrence Berkeley National Laboratory as well as Anthony Ma of Bevilacqua-Knight, Inc. This guidebook is designed as a manual for government officials and others around the world responsible for developing, implementing, enforcing, monitoring, and maintaining labeling and standards-setting programs. It discusses the pros and cons of adopting energy-efficiency labels and standards and describes the data, facilities, and institutional and human resources needed for these programs. It provides guidance on the design, development, implementation, maintenance, and evaluation of the programs

  13. Labeled nucleotide phosphate (NP) probes

    DOE Patents [OSTI]

    Korlach, Jonas; Webb, Watt W.; Levene, Michael; Turner, Stephen; Craighead, Harold G.; Foquet, Mathieu

    2009-02-03

    The present invention is directed to a method of sequencing a target nucleic acid molecule having a plurality of bases. In its principle, the temporal order of base additions during the polymerization reaction is measured on a molecule of nucleic acid, i.e. the activity of a nucleic acid polymerizing enzyme on the template nucleic acid molecule to be sequenced is followed in real time. The sequence is deduced by identifying which base is being incorporated into the growing complementary strand of the target nucleic acid by the catalytic activity of the nucleic acid polymerizing enzyme at each step in the sequence of base additions. A polymerase on the target nucleic acid molecule complex is provided in a position suitable to move along the target nucleic acid molecule and extend the oligonucleotide primer at an active site. A plurality of labelled types of nucleotide analogs are provided proximate to the active site, with each distinguishable type of nucleotide analog being complementary to a different nucleotide in the target nucleic acid sequence. The growing nucleic acid strand is extended by using the polymerase to add a nucleotide analog to the nucleic acid strand at the active site, where the nucleotide analog being added is complementary to the nucleotide of the target nucleic acid at the active site. The nucleotide analog added to the oligonucleotide primer as a result of the polymerizing step is identified. The steps of providing labelled nucleotide analogs, polymerizing the growing nucleic acid strand, and identifying the added nucleotide analog are repeated so that the nucleic acid strand is further extended and the sequence of the target nucleic acid is determined.

  14. Microsoft Word - Smart Grid Certification and Labeling Program...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... The Green Building Certification Institute also offers individuals LEED educational materials and credentials (as LEED Accredited Professionals) for those who work in the industry ...

  15. Nanomaterial Labels in Electrochemical Immunosensors and Immunoassays

    SciTech Connect (OSTI)

    Liu, Guodong; Lin, Yuehe

    2007-12-15

    This article reviews recent advances in nanomaterial labels in electrochemical immunosensors and immunoassays. Various nanomaterial labels are discussed, including colloidal gold/silver, semiconductor nanoparticles, and markers loaded nanocarriers (carbon nanotubes, apoferritin, silica nanoparticles, and liposome beads). The enormous signal enhancement associated with the use of nanomaterial labels and with the formation of nanomaterial–antibody-antigen assemblies provides the basis for ultrasensitive electrochemical detection of disease-related protein biomarkers, biothreat agents, or infectious agents. In general, all endeavors cited here are geared to achieve one or more of the following goals: signal amplification by several orders of magnitude, lower detection limits, and detecting multiple targets.

  16. Label-invariant Mesh Quality Metrics. (Conference) | SciTech...

    Office of Scientific and Technical Information (OSTI)

    Label-invariant Mesh Quality Metrics. Citation Details In-Document Search Title: Label-invariant Mesh Quality Metrics. Abstract not provided. Authors: Knupp, Patrick Publication ...

  17. ENERGY STAR Labeled Buildings and Plants | Open Energy Information

    Open Energy Info (EERE)

    STAR Labeled Buildings and Plants Jump to: navigation, search Name ENERGY STAR Labeled Buildings and Plants Data Format Excel Spreadsheet Geographic Scope United States TODO:...

  18. Radionuclide labeled lymphocytes for therapeutic use

    DOE Patents [OSTI]

    Srivastava, S.C.; Fawwaz, R.A.; Richards, P.

    1983-05-03

    Lymphocytes labelled with ..beta..-emitting radionuclides are therapeutically useful, particularly for lymphoid ablation. They are prepared by incubation of the lymphocytes with the selected radionuclide-oxine complex.

  19. Radionuclide labeled lymphocytes for therapeutic use

    DOE Patents [OSTI]

    Srivastava, Suresh C.; Fawwaz, Rashid A.; Richards, Powell

    1985-01-01

    Lymphocytes labelled with .beta.-emitting radionuclides are therapeutically useful, particularly for lymphoid ablation. They are prepared by incubation of the lymphocytes with the selected radionuclide-oxine complex.

  20. Multiple tag labeling method for DNA sequencing

    DOE Patents [OSTI]

    Mathies, Richard A.; Huang, Xiaohua C.; Quesada, Mark A.

    1995-01-01

    A DNA sequencing method described which uses single lane or channel electrophoresis. Sequencing fragments are separated in said lane and detected using a laser-excited, confocal fluorescence scanner. Each set of DNA sequencing fragments is separated in the same lane and then distinguished using a binary coding scheme employing only two different fluorescent labels. Also described is a method of using radio-isotope labels.

  1. Multiple tag labeling method for DNA sequencing

    DOE Patents [OSTI]

    Mathies, R.A.; Huang, X.C.; Quesada, M.A.

    1995-07-25

    A DNA sequencing method is described which uses single lane or channel electrophoresis. Sequencing fragments are separated in the lane and detected using a laser-excited, confocal fluorescence scanner. Each set of DNA sequencing fragments is separated in the same lane and then distinguished using a binary coding scheme employing only two different fluorescent labels. Also described is a method of using radioisotope labels. 5 figs.

  2. Entergy Arkansas- CitySmart Energy Efficiency Program

    Broader source: Energy.gov [DOE]

    No cost direct install measures include low flow aerators, low flow pre-rinse spray valves, compact fluorescent lamps, vending misers, and shower heads.

  3. Department of Energy to Take Steps to Remove ENERGY STAR Label on Certain

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    LG Refrigerator-Freezer Models | Department of Energy to Take Steps to Remove ENERGY STAR Label on Certain LG Refrigerator-Freezer Models Department of Energy to Take Steps to Remove ENERGY STAR Label on Certain LG Refrigerator-Freezer Models December 7, 2009 - 12:00am Addthis Washington, DC - The Department of Energy announced today that as part of the expanded enforcement efforts under the ENERGY STAR® program, effective January 2, 2010, certain LG French-door refrigerator-freezers are

  4. Probes labelled with energy transfer coupled dyes

    DOE Patents [OSTI]

    Mathies, R.A.; Glazer, A.; Ju, J.

    1997-11-18

    Compositions are provided comprising sets of fluorescent labels carrying pairs of donor and acceptor dye molecules, designed for efficient excitation of the donors at a single wavelength and emission from the acceptor in each of the pairs at different wavelengths. The different molecules having different donor-acceptor pairs can be modified to have substantially the same mobility under separation conditions, by varying the distance between the donor and acceptor in a given pair. Particularly, the fluorescent compositions find use as labels in sequencing nucleic acids. 7 figs.

  5. WaterSense Program: Methodology for National Water Savings Analysis Model Indoor Residential Water Use

    SciTech Connect (OSTI)

    Whitehead, Camilla Dunham; McNeil, Michael; Dunham_Whitehead, Camilla; Letschert, Virginie; della_Cava, Mirka

    2008-02-28

    The U.S. Environmental Protection Agency (EPA) influences the market for plumbing fixtures and fittings by encouraging consumers to purchase products that carry the WaterSense label, which certifies those products as performing at low flow rates compared to unlabeled fixtures and fittings. As consumers decide to purchase water-efficient products, water consumption will decline nationwide. Decreased water consumption should prolong the operating life of water and wastewater treatment facilities.This report describes the method used to calculate national water savings attributable to EPA?s WaterSense program. A Microsoft Excel spreadsheet model, the National Water Savings (NWS) analysis model, accompanies this methodology report. Version 1.0 of the NWS model evaluates indoor residential water consumption. Two additional documents, a Users? Guide to the spreadsheet model and an Impacts Report, accompany the NWS model and this methodology document. Altogether, these four documents represent Phase One of this project. The Users? Guide leads policy makers through the spreadsheet options available for projecting the water savings that result from various policy scenarios. The Impacts Report shows national water savings that will result from differing degrees of market saturation of high-efficiency water-using products.This detailed methodology report describes the NWS analysis model, which examines the effects of WaterSense by tracking the shipments of products that WaterSense has designated as water-efficient. The model estimates market penetration of products that carry the WaterSense label. Market penetration is calculated for both existing and new construction. The NWS model estimates savings based on an accounting analysis of water-using products and of building stock. Estimates of future national water savings will help policy makers further direct the focus of WaterSense and calculate stakeholder impacts from the program.Calculating the total gallons of water the

  6. Energy-Efficiency Labels and Standards: A Guidebook forAppliances, Equipment, and Lighting - 2nd Edition

    SciTech Connect (OSTI)

    Wiel, Stephen; McMahon, James E.

    2005-04-28

    Energy-performance improvements in consumer products are an essential element in any government's portfolio of energy-efficiency and climate change mitigation programs. Governments need to develop balanced programs, both voluntary and regulatory, that remove cost-ineffective, energy-wasting products from the marketplace and stimulate the development of cost-effective, energy-efficient technology. Energy-efficiency labels and standards for appliances, equipment, and lighting products deserve to be among the first policy tools considered by a country's energy policy makers. The U.S. Agency for International Development (USAID) and several other organizations identified on the cover of this guidebook recognize the need to support policy makers in their efforts to implement energy-efficiency standards and labeling programs and have developed this guidebook, together with the Collaborative Labeling and Appliance Standards Program (CLASP), as a primary reference. This second edition of the guidebook was prepared over the course of the past year, four years after the preparation of the first edition, with a significant contribution from the authors and reviewers mentioned previously. Their diligent participation helps maintain this book as the international guidance tool it has become. The lead authors would like to thank the members of the Communications Office of the Environmental Energy Technologies Division, Lawrence Berkeley National Laboratory for their support in the development, production, and distribution of the guidebook. This guidebook is designed as a manual for government officials and others around the world responsible for developing, implementing, enforcing, monitoring, and maintaining labeling and standards setting programs. It discusses the pros and cons of adopting energy-efficiency labels and standards and describes the data, facilities, and institutional and human resources needed for these programs. It provides guidance on the design, development

  7. Tc-99m Labeled carrier for imaging

    DOE Patents [OSTI]

    Henze, Eberhard

    1984-01-01

    Novel radionuclide imaging agents, having particular application for lymphangiography are provided by non-covalently binding Tc-99m to a pharmaceutically acceptable cross-linked polysaccharide. Upon injection of the Tc-99m labeled polysaccharide into the blood stream, optimum contrast can be obtained within one hour.

  8. Microfluidic Radiometal Labeling Systems for Biomolecules

    SciTech Connect (OSTI)

    Reichert, D E; Kenis, P J. A.

    2011-12-29

    In a typical labeling procedure with radiometals, such as Cu-64 and Ga-68; a very large (~ 100-fold) excess of the non-radioactive reactant (precursor) is used to promote rapid and efficient incorporation of the radioisotope into the PET imaging agent. In order to achieve high specific activities, careful control of reaction conditions and extensive chromatographic purifications are required in order to separate the labeled compounds from the cold precursors. Here we propose a microfluidic approach to overcome these problems, and achieve high specific activities in a more convenient, semi-automated fashion and faster time frame. Microfluidic reactors, consisting of a network of micron-sized channels (typical dimensions in the range 10 â�� 300 �¼m), filters, separation columns, electrodes and reaction loops/chambers etched onto a solid substrate, are now emerging as an extremely useful technology for the intensification and miniaturization of chemical processes. The ability to manipulate, process and analyze reagent concentrations and reaction interfaces in both space and time within the channel network of a microreactor provides the fine level of reaction control that is desirable in PET radiochemistry practice. These factors can bring radiometal labeling, specifically the preparation of radio-labeled biomolecules such as antibodies, much closer to their theoretical maximum specific activities.

  9. WIPP Documents - National TRU Program

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Label 1 Content 1 Label 2 Content 2 Large file size alert This symbol means the document may be a large file size. National TRU Program Annual Transuranic Waste Inventory Report - 2015 DOE/TRU-15-3425 Rev 0 Effective date 12/15 The information presented in the ATWIR - 2015 serves as a current baseline of the TRU waste inventory for potential disposal at WIPP and may be considered in future Compliance Recertification Applications. The TRU Waste Inventory Profile Reports (Appendices A and B)

  10. 99M-technetium labeled macroaggregated human serum albumin pharmaceutical

    DOE Patents [OSTI]

    Winchell, Harry S.; Barak, Morton; Van Fleet, III, Parmer

    1977-05-17

    A reagent comprising macroaggregated human serum albumin having dispersed therein particles of stannous tin and a method for instantly making a labeled pharmaceutical therefrom, are disclosed. The labeled pharmaceutical is utilized in organ imaging.

  11. Lumens and the Lighting Facts Label | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    It helps people buy the lightbulbs that are right for them. Like the helpful nutrition label on food products, the Lighting Facts label helps consumers understand what they are ...

  12. An introduction to the National Tritium Labeling Facility

    SciTech Connect (OSTI)

    Dorsky, A.M.; Morimoto, H.; Saljoughian, M.; Williams, P.G.; Rapoport, H.

    1988-06-01

    The facilities and projects of the National Tritium Labeling Facility are described. 5 refs., 1 fig., 1 tab.

  13. Colloid labelled with radionuclide and method

    DOE Patents [OSTI]

    Atcher, R.W.; Hines, J.J.

    1990-11-13

    A ferric hydroxide colloid having an alpha-emitting radionuclide essentially on the outer surfaces and a method of forming same. The method includes oxidizing a ferrous hydroxide to ferric hydroxide in the presence of a preselected radionuclide to form a colloid having the radionuclide on the outer surface thereof, and thereafter washing the colloid, and suspending the washed colloid in a suitable solution. The labelled colloid is useful in cancer therapy and for the treatment of inflamed joints. No Drawings

  14. North America Energy Efficiency Standards and Labeling

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    North American Energy Efficiency Standards and Labeling North American Energy Working Group NORTH AMERICAN ENERGY WORKING GROUP The North American Energy Working Group (NAEWG) was established in spring of 2001 by the Canadian Minister of Natural Resources, the Mexican Secretary of Energy and the U.S. Secretary of Energy, to enhance North American energy cooperation. The Group is led by officials from Natural Resources Canada, the Mexican Secretariat of Energy, and the U.S. Department of Energy.

  15. Method of making colloid labeled with radionuclide

    DOE Patents [OSTI]

    Atcher, Robert W.; Hines, John J.

    1991-01-01

    A ferric hydroxide colloid having an alpha-emitting radionuclide essentially on the outer surfaces and a method of forming same. The method includes oxidizing a ferrous hydroxide to ferric hydroxide in the presence of a preselected radionuclide to form a colloid having the radionuclide on the outer surface thereof, and thereafter washing the colloid, and suspending the washed colloid in a suitable solution. The labelled colloid is useful in cancer therapy and for the treatment of inflamed joints.

  16. Colloid labelled with radionuclide and method

    DOE Patents [OSTI]

    Atcher, Robert W.; Hines, John J.

    1990-01-01

    A ferric hydroxide colloid having an alpha-emitting radionuclide essentially on the outer surfaces and a method of forming same. The method includes oxidizing a ferrous hydroxide to ferric hydroxide in the presence of a preselected radionuclide to form a colloid having the radionuclide on the outer surface thereof, and thereafter washing the colloid, and suspending the washed colloid in a suitable solution. The labelled colloid is useful in cancer therapy and for the treatment of inflamed joints.

  17. CFL Labeling Harmonization in the United States, China, Brazil andELI Member Countries: Specifications, Testing, and MutualRecognition

    SciTech Connect (OSTI)

    Fridley, David; Lin, Jiang; Denver, Andrea; Biermayer, Peter; Dillavou, Tyler

    2005-07-20

    This report examines critical differences among energy-efficient labeling programs for CFLs in Brazil, China, the United States, and the seven members of the international Efficient Lighting Initiative (ELI) in terms of technical specifications and test procedures, and review issues related to international harmonization of these standards.

  18. convert program

    National Nuclear Security Administration (NNSA)

    %2A en Nuclear Material Removal http:www.nnsa.energy.govaboutusourprogramsdnnm3remove

    label">Pag...

  19. convert program

    National Nuclear Security Administration (NNSA)

    %2A en Nuclear Material Removal http:nnsa.energy.govaboutusourprogramsdnnm3remove

    label">Page...

  20. CD Label and Package Templates | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Publications, Exhibits, & Logos » Templates » CD Label and Package Templates CD Label and Package Templates The Office of Energy Efficiency and Renewable Energy (EERE) has developed templates for CD labels and CD packages. These can be used for all EERE products. Both templates are available as EPS files, which can be downloaded and edited in a graphics package like Adobe Illustrator. You are not required to use these templates for your EERE products. These templates were designed to allow

  1. Efficient and selective isotopic labeling of hemes to facilitate...

    Office of Scientific and Technical Information (OSTI)

    This method achieves, in a single step, efficient expression and incorporation of hemes isotopically labeled in specific atom positions adequate for spectroscopic characterization ...

  2. Widget:LabelMandatoryFields | Open Energy Information

    Open Energy Info (EERE)

    Jump to: navigation, search This widget labels any mandatory form fields with a red asterik. Matches on css selectors formtable and mandatoryField. Retrieved from "http:...

  3. Beryllium-7 labeled carbon particles and method of making

    DOE Patents [OSTI]

    Richards, P.; Mausner, L.F.; Prach, T.F.

    1987-11-17

    Beryllium-7 labeled carbon particles made from the proton irradiation of carbon materials, preferably from dry carbon black are disclosed. Such particles are useful as gamma emitting radiotracers.

  4. Beryllium-7 labeled carbon particles and method of making

    DOE Patents [OSTI]

    Richards, Powell; Mausner, Leonard F.; Prach, Thomas F.

    1987-01-01

    Beryllium-7 labeled carbon particles made from the proton irradiation of carbon materials, preferably from dry carbon black are disclosed. Such particles are useful as gamma emitting radiotracers.

  5. Energy Efficiency Labeling System & its Development in China...

    Broader source: Energy.gov (indexed) [DOE]

    of energy efficiency labeling in China. session1buildingstrackchengjianhong... Status Prospects of Green Data Center 4th U.S.-China Energy Efficiency Forum Documents ...

  6. Beryllium-7 labeled carbon particles and method of making

    DOE Patents [OSTI]

    Richards, P.; Mausner, L.F.; Prach, T.F.

    1985-04-29

    Beryllium-7 labeled carbon particles made from the proton irradiation of carbon materials, preferably from dry carbon black are disclosed. Such particles are useful as gamma emitting radiotracers.

  7. Lumens and the Lighting Facts Label | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Lumens and the Lighting Facts Label Lumens and the Lighting Facts Label Energy 101 Lumens: The new way to shop for light lighting_sub.jpg When you're shopping for lightbulbs, compare lumens to be sure you're getting the amount of light, or level of brightness, you want. The Lighting Facts Label will help. This new label will make it easy to compare bulb brightness, color, life, and estimated operating cost for the year. Buy Lumens, Not Watts In the past, we bought lightbulbs based on how much

  8. Regional cooperation in energy efficiency standard-setting and labeling in North America

    SciTech Connect (OSTI)

    Wiel, Stephen; Van Wie McGrory, Laura

    2003-08-04

    The North American Energy Working Group (NAEWG) was established in 2001 by the governments of Canada, Mexico, and the United States. The goals of NAEWG are to foster communication and cooperation on energy-related matters of common interest, and to enhance North American energy trade and interconnections consistent with the goal of sustainable development, for the benefit of all three countries. At its outset, NAEWG established teams to address different aspects of the energy sector. One, the Energy Efficiency Expert Group, undertook activity in three areas: (1) analyzing commonalities and differences in the test procedures of Canada, Mexico, and the United States, and identifying specific products for which the three countries might consider harmonization; (2) exploring possibilities for increased mutual recognition of laboratory test results; and (3) looking at possibilities for enhanced cooperation in the Energy Star voluntary endorsement labeling program. To support NAEWG's Expert Group on Energy Efficiency (NAEWG-EE), USDOE commissioned Lawrence Berkeley National Laboratory, representing the Collaborative Labeling and Appliance Standards Program (CLASP), to prepare a resource document comparing current standards, labels, and test procedure regulations in Canada, Mexico, and the United States. The resulting document identified 46 energy-using products for which at least one of the three countries has energy efficiency regulations. Three products--refrigerators/freezers, room air conditioners, and integral horsepower three-phase electric motors--have identical minimum energy performance standards (MEPS) and test procedures in the three countries. Ten other products have different MEPS and test procedures, but have the near-term potential for harmonization. NAEWG-EE is currently working to identify mechanisms for mutual recognition of test results. With consultative support from the United States and Canada through NAEWG-EE, Mexico is exploring possibilities for

  9. SEP Program Planning Template ("Program Planning Template") ...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    SEP Program Planning Template ("Program Planning Template") SEP Program Planning Template ("Program Planning Template") Program Planning Template More Documents & Publications...

  10. Program Evaluation: Program Life Cycle

    Broader source: Energy.gov [DOE]

    In general, different types of evaluation are carried out over different parts of a program's life cycle (e.g., Creating a program, Program is underway, or Closing out or end of program)....

  11. Labeling of indocyanine green with carrier-free iodine-123

    DOE Patents [OSTI]

    Ansari, Azizullah N.; Lambrecht, Richard M.; Redvanly, Carol S.; Wolf, Alfred P.

    1976-01-01

    The method of labeling indocyanine green (ICG) with carrier-free iodine-123 comprising the steps of condensing xenon-123 on crystals of ICG followed by permitting decay of the .sup.123 Xe a sufficient length of time to produce .sup.123 I-electronically excited ions and atoms which subsequently label ICG.

  12. Tritium labeling of organic compounds deposited on porous structures

    DOE Patents [OSTI]

    Ehrenkaufer, Richard L. E.; Wolf, Alfred P.; Hembree, Wylie C.

    1979-01-01

    An improved process for labeling organic compounds with tritium is carried out by depositing the selected compound on the extensive surface of a porous structure such as a membrane filter and exposing the membrane containing the compound to tritium gas activated by the microwave discharge technique. The labeled compound is then recovered from the porous structure.

  13. Holographic Labeling And Reading Machine For Authentication And Security Appications

    DOE Patents [OSTI]

    Weber, David C.; Trolinger, James D.

    1999-07-06

    A holographic security label and automated reading machine for marking and subsequently authenticating any object such as an identification badge, a pass, a ticket, a manufactured part, or a package is described. The security label is extremely difficult to copy or even to read by unauthorized persons. The system comprises a holographic security label that has been created with a coded reference wave, whose specification can be kept secret. The label contains information that can be extracted only with the coded reference wave, which is derived from a holographic key, which restricts access of the information to only the possessor of the key. A reading machine accesses the information contained in the label and compares it with data stored in the machine through the application of a joint transform correlator, which is also equipped with a reference hologram that adds additional security to the procedure.

  14. Synthesis of labeled oxalic acid derivatives

    DOE Patents [OSTI]

    Martinez, Rodolfo A.; Unkefer, Clifford J.; Alvarez, Marc A.

    2004-06-22

    The present invention is directed to labeled compounds, specifically ##STR1## where each C* is selected from the group consisting of a carbon-12, i.e., .sup.12 C, or a carbon-13, i.e., .sup.13 C and at least one C* is .sup.13 C, R.sup.1 is selected from the group of C.sub.1 -C.sub.4 lower alkyl and aryl, and X is selected from the group of --NR.sup.2 R.sup.3 where R.sup.2 and R.sup.3 are each independently selected from the group of C.sub.1 -C.sub.4 lower alkyl, alkoxy and aryl, --SR.sup.4 where R.sup.4 is selected from the group of C.sub.1 -C.sub.4 lower alkyl, alkoxy and aryl, and --OR.sup.5 where R.sup.5 is selected from the group of C.sub.1 -C.sub.4 lower alkyl, alkoxy and aryl with the proviso that when R.sup.1 is methyl then R.sup.5 is other than methyl, when R.sup.1 is ethyl then R.sup.5 is other than ethyl, and when R.sup.1 is benzyl then R.sup.5 is other than benzyl.

  15. A New Generation of Labels for a New Generation of Cars | Department...

    Energy Savers [EERE]

    A New Generation of Labels for a New Generation of Cars A New Generation of Labels for a New Generation of Cars May 25, 2011 - 5:42pm Addthis A New Generation of Labels for a New ...

  16. Program Administration

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1997-08-21

    This volume describes program administration that establishes and maintains effective organizational management and control of the emergency management program. Canceled by DOE G 151.1-3.

  17. Weatherization Program

    Broader source: Energy.gov [DOE]

    Residences participating in the Home Energy Rebate or New Home Rebate Program may not also participate in the Weatherization Program. 

  18. Visiting Faculty Program Program Description

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Visiting Faculty Program Program Description The Visiting Faculty Program seeks to increase the research competitiveness of faculty members and their students at institutions historically underrepresented in the research community in order to expand the workforce vital to Department of Energy mission areas. As part of the program, selected university/college faculty members collaborate with DOE laboratory research staff on a research project of mutual interest. Program Objective The program is

  19. 99M-Technetium labeled tin colloid radiopharmaceuticals

    DOE Patents [OSTI]

    Winchell, Harry S.; Barak, Morton; Van Fleet, III, Parmer

    1976-07-06

    An improved 99m-technetium labeled tin(II) colloid, size-stabilized for reticuloendothelial organ imaging without the use of macromolecular stabilizers and a packaged tin base reagent and an improved method for making it are disclosed.

  20. Template:LabelValuePair | Open Energy Information

    Open Energy Info (EERE)

    is typically used to display the results of an ask or sparql query in a simple label: value format. It is used by many pages, including the sub pages for country profiles, and is...

  1. LED Lighting Facts® Program Supports Accuracy in SSL Product Information

    SciTech Connect (OSTI)

    2013-09-30

    Fact sheet that provides a summary of LED Lighting Facts, a program to assure that LED lighting is accurately represented in the marketplace, illustrated by the LED Lighting Facts label to disclose product performance data.

  2. Self-assessed performance improves statistical fusion of image labels

    SciTech Connect (OSTI)

    Bryan, Frederick W. Xu, Zhoubing; Asman, Andrew J.; Allen, Wade M.; Reich, Daniel S.; Landman, Bennett A.

    2014-03-15

    Purpose: Expert manual labeling is the gold standard for image segmentation, but this process is difficult, time-consuming, and prone to inter-individual differences. While fully automated methods have successfully targeted many anatomies, automated methods have not yet been developed for numerous essential structures (e.g., the internal structure of the spinal cord as seen on magnetic resonance imaging). Collaborative labeling is a new paradigm that offers a robust alternative that may realize both the throughput of automation and the guidance of experts. Yet, distributing manual labeling expertise across individuals and sites introduces potential human factors concerns (e.g., training, software usability) and statistical considerations (e.g., fusion of information, assessment of confidence, bias) that must be further explored. During the labeling process, it is simple to ask raters to self-assess the confidence of their labels, but this is rarely done and has not been previously quantitatively studied. Herein, the authors explore the utility of self-assessment in relation to automated assessment of rater performance in the context of statistical fusion. Methods: The authors conducted a study of 66 volumes manually labeled by 75 minimally trained human raters recruited from the university undergraduate population. Raters were given 15 min of training during which they were shown examples of correct segmentation, and the online segmentation tool was demonstrated. The volumes were labeled 2D slice-wise, and the slices were unordered. A self-assessed quality metric was produced by raters for each slice by marking a confidence bar superimposed on the slice. Volumes produced by both voting and statistical fusion algorithms were compared against a set of expert segmentations of the same volumes. Results: Labels for 8825 distinct slices were obtained. Simple majority voting resulted in statistically poorer performance than voting weighted by self-assessed performance

  3. Visiting Faculty Program Program Description

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    covers stipend and travel reimbursement for the 10-week program. Teacherfaculty participants: 1 Program Coordinator: Scott Robbins Email: srobbins@lanl.gov Phone number: 663-5621...

  4. Hanford Site Beryllium Posting and Labeling Requirements Procedure

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    -003 Revision 1 Hanford Site Beryllium Posting and Labeling Requirements Procedure Prepared for the U.S. Department of Energy Assistant Secretary for Environmental Management Approved for Public Release; Further Dissemination Unlimited DOE-0342-003, Rev. 1 Hanford Site Beryllium Posting and Labeling Requirements Procedure Published Date: 09-19-2013 Effective Date: 05-14-2014 Change Summary Page 1 of 1 Change Summary Revision # Date/Section Changed Change Details 1 3/19/13, Misc. changes as

  5. Posting and Labeling for Radiological Control Guide for use with Title 10, Code of Federal Regulations, Part 835, Occupational Radiation Protection

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1999-05-24

    This Guide provides an acceptable methodology for establishing and operating a radiological hazard posting and labeling program that will comply with U.S. Department of Energy (DOE) requirements specified in Title 10 of the Code of Federal Regulations (CFR), Part 835, Occupational Radiation Protection Canceled by DOE G 441.1-1B.

  6. Community Programs

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Community Programs Community Environmental Documents Tours Community Programs Friends of Berkeley Lab ⇒ Navigate Section Community Environmental Documents Tours Community Programs Friends of Berkeley Lab Community Education Programs Workforce Development & Education As part of the Lab's education mission to inspire and prepare the next generation of scientists and engineers, the Workforce Development & Education runs numerous education programs for all ages of students-from elementary

  7. Light Water Reactor Sustainability Program - Integrated Program...

    Office of Environmental Management (EM)

    Program - Integrated Program Plan Light Water Reactor Sustainability Program - Integrated Program Plan The Light Water Reactor Sustainability (LWRS) Program is a research and ...

  8. Retiree Program

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Library Services » Retiree Program Retiree Program The Research Library offers a 1 year library card to retired LANL employees that allows usage of Library materials. This service is only available to retired LANL employees. Who is eligible? Any Laboratory retiree, not participating in any other program (ie, Guest Scientist, Affiliate). Upon completion of your application, you will be notified of your acceptance into the program. This does not include past students. What is the term of the

  9. HVAC Program

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    New Commercial Program Development Commercial Current Promotions Industrial Federal Agriculture Heating Ventilation and Air Conditioning Energy efficient Heating Ventilation and...

  10. Data-Parallel Mesh Connected Components Labeling and Analysis

    SciTech Connect (OSTI)

    Harrison, Cyrus; Childs, Hank; Gaither, Kelly

    2011-04-10

    We present a data-parallel algorithm for identifying and labeling the connected sub-meshes within a domain-decomposed 3D mesh. The identification task is challenging in a distributed-memory parallel setting because connectivity is transitive and the cells composing each sub-mesh may span many or all processors. Our algorithm employs a multi-stage application of the Union-find algorithm and a spatial partitioning scheme to efficiently merge information across processors and produce a global labeling of connected sub-meshes. Marking each vertex with its corresponding sub-mesh label allows us to isolate mesh features based on topology, enabling new analysis capabilities. We briefly discuss two specific applications of the algorithm and present results from a weak scaling study. We demonstrate the algorithm at concurrency levels up to 2197 cores and analyze meshes containing up to 68 billion cells.

  11. Understanding the Environmental Impacts of Electricity: Product Labeling and Certification

    SciTech Connect (OSTI)

    Bird, L.

    2003-01-01

    Electricity consumers are increasingly gaining the ability to choose among power options from either their current electric utilities or from alternative power providers. In order to help consumers make informed decisions about their electricity purchases and to compare alternatives, many states are requiring electricity providers to disclose information regarding the fuel sources used to generate electricity and the associated environmental impacts. Like nutrition labels, environmental disclosure labels present the content or sources of electricity and are typically included with electricity bills and in product offers. These labels allow consumers to compare the environmental impacts of standard and cleaner power options, which are typically available. This paper discusses clean, green power options available to power purchasers and the tools and information that can be used to make more sustainable power purchase decisions.

  12. Simple, rapid method for the preparation of isotopically labeled formaldehyde

    DOE Patents [OSTI]

    Hooker, Jacob Matthew; Schonberger, Matthias; Schieferstein, Hanno; Fowler, Joanna S.

    2011-10-04

    Isotopically labeled formaldehyde (*C.sup..sctn.H.sub.2O) is prepared from labeled methyl iodide (*C.sup..sctn.H.sub.3I) by reaction with an oxygen nucleophile having a pendant leaving group. The mild and efficient reaction conditions result in good yields of *C.sup..sctn.H.sub.2O with little or no *C isotopic dilution. The simple, efficient production of .sup.11CH.sub.2O is described. The use of the .sup.11CH.sub.2O for the formation of positron emission tomography tracer compounds is described. The reaction can be incorporated into automated equipment available to radiochemistry laboratories. The isotopically labeled formaldehyde can be used in a variety of reactions to provide radiotracer compounds for imaging studies as well as for scintillation counting and autoradiography.

  13. Semiconductor Quantum Rods as Single Molecule FluorescentBiological Labels

    SciTech Connect (OSTI)

    Fu, Aihua; Gu, Weiwei; Boussert, Benjamine; Koski, Kristie; Gerion, Daniele; Manna, Liberato; Le Gros, Mark; Larabell, Carolyn; Alivisatos, A. Paul

    2006-05-29

    In recent years, semiconductor quantum dots have beenapplied with great advantage in a wide range of biological imagingapplications. The continuing developments in the synthesis of nanoscalematerials and specifically in the area of colloidal semiconductornanocrystals have created an opportunity to generate a next generation ofbiological labels with complementary or in some cases enhanced propertiescompared to colloidal quantum dots. In this paper, we report thedevelopment of rod shaped semiconductor nanocrystals (quantum rods) asnew fluorescent biological labels. We have engineered biocompatiblequantum rods by surface silanization and have applied them fornon-specific cell tracking as well as specific cellular targeting. Theproperties of quantum rods as demonstrated here are enhanced sensitivityand greater resistance for degradation as compared to quantum dots.Quantum rods have many potential applications as biological labels insituations where their properties offer advantages over quantumdots.

  14. Green lights program in China

    SciTech Connect (OSTI)

    Dadi, Zhuo; Hong, Liu

    1996-12-31

    In China`s 9th 5-year plan (1996-2000), the Chinese government has placed high priority on energy conservation. The China Green Lights Program (CGLP) is listed as one of the key projects of energy conservation. The basic strategy of the CGLP is to mobilise all of the potential contributors to participate in the program, and to use market signals and supplementary non-market instruments to facilitate its implementation. Governmental funds and loans will be used as seed money to attract private participation in the program. The program contains the following elements: (1) Information dissemination to educate the public on the economic and other values of the program and to provide CGLP information to increase consumer awareness and, as a result, increase the demand for energy-efficient lighting systems. (2) Development of standards and codes for lighting systems, establishment of product specifications, and enforcement of product standards. (3) Development of quality certification and labelling system to provide assurances to consumers that the products they are purchasing will meet their performance and cost saving expectations. (4) Highlighted support and financing for production technology development and production capacity expansion. (5) Demonstration and pilot projects to boost consumer confidence in green lighting systems and to demonstrate new production technologies and processes. (6) International co-operation to expand the international exchange and absorb advanced technology and experience for implementation of the China Green Lights Program.

  15. Status and future directions of the ENERGY STAR program

    SciTech Connect (OSTI)

    Brown, Richard E.; Webber, Carrie A.; Koomey, Jonathan G.

    2000-06-19

    In 1992 the U.S. Environmental Protection Agency (EPA) introduced ENERGY STAR (registered trademark), a voluntary labeling program designed to identify and promote energy-efficient products, in order to reduce carbon dioxide emissions. Since then EPA, now in partnership with the U.S. Department of Energy (DOE), has expanded the program to cover nearly the entire buildings sector, spanning new homes, commercial buildings, residential heating and cooling equipment, major appliances, office equipment, commercial and residential lighting, and home electronics. This paper provides a snapshot of the ENERGY STAR program in the year 2000, including a general overview of the program, its accomplishments, and the possibilities for future development. First, we describe the products that are currently eligible for the ENERGY STAR label and the program mechanisms that EPA and DOE are using to promote these products. Second, we illustrate selected milestones achieved in some markets, and ways that EPA and DOE are responding to challenges or changes in certain markets. Third, we discuss the evolving ENERGY STAR brand strategy. Next, we explore ways in which ENERGY STAR interacts with and enhances other policies, such as appliance standards and regional market transformation collaboratives. We then discuss evaluation studies that EPA and DOE are undertaking to quantify the impact of the ENERGY STAR program. Finally, we discuss future areas of expansion for the ENERGY STAR program, including labeling of new products and integrated programs for commercial and existing residential buildings.

  16. Volume-labeled nanoparticles and methods of preparation

    SciTech Connect (OSTI)

    Wang, Wei; Gu, Baohua; Retterer, Scott T; Doktycz, Mitchel J

    2015-04-21

    Compositions comprising nanosized objects (i.e., nanoparticles) in which at least one observable marker, such as a radioisotope or fluorophore, is incorporated within the nanosized object. The nanosized objects include, for example, metal or semi-metal oxide (e.g., silica), quantum dot, noble metal, magnetic metal oxide, organic polymer, metal salt, and core-shell nanoparticles, wherein the label is incorporated within the nanoparticle or selectively in a metal oxide shell of a core-shell nanoparticle. Methods of preparing the volume-labeled nanoparticles are also described.

  17. Program Description

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Program Description SAGE, the Summer of Applied Geophysical Experience, is a unique educational program designed to introduce students in geophysics and related fields to "hands on" geophysical exploration and research. The program emphasizes both teaching of field methods and research related to basic science and a variety of applied problems. SAGE is hosted by the National Security Education Center and the Earth and Environmental Sciences Division of the Los Alamos National

  18. Counterintelligence Program

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1992-09-04

    To establish the policies, procedures, and specific responsibilities for the Department of Energy (DOE) Counterintelligence (CI) Program. This directive does not cancel any other directive.

  19. Program Description

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Applied Geophysical Experience, is a unique educational program designed to introduce students in geophysics and related fields to "hands on" geophysical exploration and research....

  20. Programming Stage

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1997-05-21

    This chapter addresses plans for the acquisition and installation of operating environment hardware and software and design of a training program.

  1. Program Description

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    their potential and pursue opportunities in science, technology, engineering and mathematics. Through Expanding Your Horizon (EYH) Network programs, we provide STEM role models...

  2. Volunteer Program

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    National VolunteerMatch Retired and Senior Volunteer Program United Way of Northern New Mexico United Way of Santa Fe County Giving Employee Giving Campaign Holiday Food Drive...

  3. exercise program

    National Nuclear Security Administration (NNSA)

    and dispose of many different hazardous substances, including radioactive materials, toxic chemicals, and biological agents and toxins.

    There are a few programs NNSA uses...

  4. Counterintelligence Program

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2004-12-10

    The Order establishes Counterintelligence Program requirements and responsibilities for the Department of Energy, including the National Nuclear Security Administration. Supersedes DOE 5670.3.

  5. Program Description

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Program Description Inspiring girls to recognize their potential and pursue opportunities in science, technology, engineering and mathematics. Through Expanding Your Horizon (EYH) ...

  6. Special Programs

    Office of Energy Efficiency and Renewable Energy (EERE)

    Headquarters Human Resources Operations promotes a variety of hiring flexibilities for managers to attract a diverse workforce, from Student Internship Program opportunities (Pathways), Veteran...

  7. IMPACTS: Industrial Technologies Program, Summary of Program...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    IMPACTS: Industrial Technologies Program, Summary of Program Results for CY2009 IMPACTS: Industrial Technologies Program, Summary of Program Results for CY2009 ...

  8. Palladium-109 labeled anti-melanoma monoclonal antibodies

    DOE Patents [OSTI]

    Srivastava, S.C.; Fawwaz, R.A.; Ferrone, S.

    1984-04-30

    The invention consists of new monoclonal antibodies labelled with Palladium 109, a beta-emitting radionuclide, the method of preparing this material, and its use in the radiotherapy of melanoma. The antibodies are chelate-conjugated and demonstrate a high uptake in melanomas. (ACR)

  9. Isonitrile radionuclide complexes for labelling and imaging agents

    DOE Patents [OSTI]

    Jones, Alun G.; Davison, Alan; Abrams, Michael J.

    1984-06-04

    A coordination complex of an isonitrile ligand and radionuclide such as Tc, Ru, Co, Pt, Fe, Os, Ir, W, Re, Cr, Mo, Mn, Ni, Rh, Pd, Nb and Ta, is useful as a diagnostic agent for labelling liposomes or vesicles, and selected living cells containing lipid membranes, such as blood clots, myocardial tissue, gall bladder tissue, etc.

  10. Student Internship Programs Program Description

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Student Internship Programs Program Description The objective of the Laboratory's student internship programs is to provide students with opportunities for meaningful hands- on experience supporting educational progress in their selected scientific or professional fields. The most significant impact of these internship experiences is observed in the intellectual growth experienced by the participants. Student interns are able to appreciate the practical value of their education efforts in their

  11. Program Description | Robotics Internship Program

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    March 4, 2016. Apply Now for the Robotics Internship About the Internship Program Description Start of Appointment Renewal of Appointment End of Appointment Stipend Information...

  12. New Lighting Facts Label: Takes the Guess Work Out of Shopping...

    Energy Savers [EERE]

    New Lighting Facts Label: Takes the Guess Work Out of Shopping for Light Bulbs New Lighting Facts Label: Takes the Guess Work Out of Shopping for Light Bulbs January 25, 2012 - ...

  13. Methods to radiolabel natural organic matter by reduction with hydrogen labeled reducing agents

    DOE Patents [OSTI]

    Tinnacher, Ruth M.; Honeyman, Bruce D.

    2011-10-18

    Methods to radiolabel natural organic matter by reduction with a hydrogen labeled reducing agent, and compositions, are provided.

  14. The Practice and Thinking of Building Energy Efficiency Evaluation & Labeling in Shanghai

    Broader source: Energy.gov [DOE]

    Information about the development of Building Energy Efficiency Evaluation and Labeling in Shanghai with project examples and theory.

  15. Science Programs

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The focal point for basic and applied R&D programs with a primary focus on energy but also encompassing medical, biotechnology, high-energy physics, and advanced scientific ...

  16. Programming models

    SciTech Connect (OSTI)

    Daniel, David J; Mc Pherson, Allen; Thorp, John R; Barrett, Richard; Clay, Robert; De Supinski, Bronis; Dube, Evi; Heroux, Mike; Janssen, Curtis; Langer, Steve; Laros, Jim

    2011-01-14

    A programming model is a set of software technologies that support the expression of algorithms and provide applications with an abstract representation of the capabilities of the underlying hardware architecture. The primary goals are productivity, portability and performance.

  17. Program Overview

    Broader source: Energy.gov [DOE]

    The culture of the DOE community will be based on standards. Technical standards will formally integrate part of all DOE facility, program and project activities. The DOE will be recognized as a...

  18. Deconvolution Program

    Energy Science and Technology Software Center (OSTI)

    1999-02-18

    The program is suitable for a lot of applications in applied mathematics, experimental physics, signal analytical system and some engineering applications range i.e. deconvolution spectrum, signal analysis and system property analysis etc.

  19. Integrated Program

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Program Review (IPR) Quarterly Business Review (QBR) Access to Capital Debt Management July 2013 Aug. 2013 Sept. 2013 Oct. 2013 Nov. 2013 Dec. 2013 Jan. 2014 Feb. 2014 March...

  20. Program Analyst

    Broader source: Energy.gov [DOE]

    A successful candidate in this position will serve as an Program Analyst for the System Operations team in the area of regulatory compliance. The successful candidate will also become a subject...

  1. Single step signal group-imidazole labeling of organic phosphate groups under aqueous conditions

    DOE Patents [OSTI]

    Giese, R.W.; Wang, P.

    1996-04-30

    Compounds and methods for single step, covalent labeling of the phosphate group of an organic substance under aqueous conditions are described. The labeling compound includes any kind of detectable signal group covalently bound to an imidazole moiety, which can be imidazole or a substituted imidazole. A preferred labeling compound has the formula shown in the accompanying diagram. 4 figs.

  2. Single step signal group-imidazole labeling of organic phosphate groups under aqueous conditions

    DOE Patents [OSTI]

    Giese, Roger W.; Wang, Poguang

    1996-01-01

    Compounds and methods for single step, covalent labeling of the phosphate group of an organic substance under aqueous conditions are described. The labeling compound includes any kind of detectable signal group covalently bound to an imidazole moiety, which can be imidazole or a substituted imidazole. A preferred labeling compound has the formula ##STR1##

  3. Assay for vitamin B12 absorption and method of making labeled vitamin B12

    SciTech Connect (OSTI)

    Anderson, Peter J.; Dueker, Stephen; Miller, Joshua; Green, Ralph; Roth, John; Carkeet, Colleen; Buchholz,; Bruce A.

    2012-06-19

    The invention provides methods for labeling vitamin B12 with .sup.14C, .sup.13C, tritium, and deuterium. When radioisotopes are used, the invention provides for methods of labeling B12 with high specific activity. The invention also provides labeled vitamin B12 compositions made in accordance with the invention.

  4. Microfabricated capillary electrophoresis chip and method for simultaneously detecting multiple redox labels

    DOE Patents [OSTI]

    Mathies, Richard A.; Singhal, Pankaj; Xie, Jin; Glazer, Alexander N.

    2002-01-01

    This invention relates to a microfabricated capillary electrophoresis chip for detecting multiple redox-active labels simultaneously using a matrix coding scheme and to a method of selectively labeling analytes for simultaneous electrochemical detection of multiple label-analyte conjugates after electrophoretic or chromatographic separation.

  5. Educational Programs

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Educational Programs Educational Programs A collaboration between Los Alamos National Laboratory and the University of California at San Diego (UCSD) Jacobs School of Engineering Contact Institute Director Charles Farrar (505) 663-5330 Email UCSD EI Director Michael Todd (858) 534-5951 Professional Staff Assistant Ellie Vigil (505) 667-2818 Email Administrative Assistant Rebecca Duran (505) 665-8899 Email There are two educational components to the Engineering Institute. The Los Alamos Dynamic

  6. Program Leadership

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Program Leadership - Sandia Energy Energy Search Icon Sandia Home Locations Contact Us Employee Locator Energy & Climate Secure & Sustainable Energy Future Stationary Power Energy Conversion Efficiency Solar Energy Wind Energy Water Power Supercritical CO2 Geothermal Natural Gas Safety, Security & Resilience of the Energy Infrastructure Energy Storage Nuclear Power & Engineering Grid Modernization Battery Testing Nuclear Energy Defense Waste Management Programs Advanced Nuclear

  7. Program Summaries

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Program Summaries Basic Energy Sciences (BES) BES Home About Research Facilities Science Highlights Benefits of BES Funding Opportunities Basic Energy Sciences Advisory Committee (BESAC) Community Resources Program Summaries Brochures Reports Accomplishments Presentations BES and Congress Science for Energy Flow Seeing Matter Nano for Energy Scale of Things Chart Contact Information Basic Energy Sciences U.S. Department of Energy SC-22/Germantown Building 1000 Independence Ave., SW Washington,

  8. Volunteer Program

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Volunteer Program Volunteer Program Our good neighbor pledge includes active employee engagement in our communities through volunteering. More than 3,000 current and retired Lab employees have logged more than 1.8 million volunteer hours since 2007. August 19, 2015 Los Alamos National Laboratory employee volunteers with Mountain Canine Corps Lab employee Debbi Miller volunteers for the Mountain Canine Corps with her search and rescue dogs. She also volunteers with another search and rescue

  9. Labeled ALPHA4BETA2 ligands and methods therefor

    DOE Patents [OSTI]

    Mukherjee, Jogeshwar; Pichika, Ramaiah; Potkin, Steven; Leslie, Frances; Chattopadhyay, Sankha

    2013-02-19

    Contemplated compositions and methods are employed to bind in vitro and in vivo to an .alpha.4.beta.2 nicotinic acetylcholine receptor in a highly selective manner. Where such compounds are labeled, compositions and methods employing such compounds can be used for PET and SPECT analysis. Alternatively, and/or additionally contemplated compounds can be used as antagonists, partial agonists or agonists in the treatment of diseases or conditions associated with .alpha.4.beta..beta.2 dysfunction.

  10. Deep Learning in Label-free Cell Classification

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Chen, Claire Lifan; Mahjoubfar, Ata; Tai, Li-Chia; Blaby, Ian K.; Huang, Allen; Niazi, Kayvan Reza; Jalali, Bahram

    2016-03-15

    Label-free cell analysis is essential to personalized genomics, cancer diagnostics, and drug development as it avoids adverse effects of staining reagents on cellular viability and cell signaling. However, currently available label-free cell assays mostly rely only on a single feature and lack sufficient differentiation. Also, the sample size analyzed by these assays is limited due to their low throughput. Here, we integrate feature extraction and deep learning with high-throughput quantitative imaging enabled by photonic time stretch, achieving record high accuracy in label-free cell classification. Our system captures quantitative optical phase and intensity images and extracts multiple biophysical features of individualmore » cells. These biophysical measurements form a hyperdimensional feature space in which supervised learning is performed for cell classification. We compare various learning algorithms including artificial neural network, support vector machine, logistic regression, and a novel deep learning pipeline, which adopts global optimization of receiver operating characteristics. As a validation of the enhanced sensitivity and specificity of our system, we show classification of white blood T-cells against colon cancer cells, as well as lipid accumulating algal strains for biofuel production. In conclusion, this system opens up a new path to data-driven phenotypic diagnosis and better understanding of the heterogeneous gene expressions in cells.« less

  11. Student Internship Programs Program Description

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    for a summer high school student to 75,000 for a Ph.D. student working full-time for a year. Program Coordinator: Scott Robbins Email: srobbins@lanl.gov Phone number: 663-5621...

  12. Postdoctoral Program Program Description The Postdoctoral (Postdoc...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Postdoctoral Program Program Description The Postdoctoral (Postdoc) Research program offers the opportunity for appointees to perform research in a robust scientific R&D...

  13. Progress towards Managing Residential Electricity Demand: Impacts of Standards and Labeling for Refrigerators and Air Conditioners in India

    SciTech Connect (OSTI)

    McNeil, Michael A.; Iyer, Maithili

    2009-05-30

    The development of Energy Efficiency Standards and Labeling (EES&L) began in earnest in India in 2001 with the Energy Conservation Act and the establishment of the Indian Bureau of Energy Efficiency (BEE). The first main residential appliance to be targeted was refrigerators, soon to be followed by room air conditioners. Both of these appliances are of critical importance to India's residential electricity demand. About 15percent of Indian households own a refrigerator, and sales total about 4 million per year, but are growing. At the same time, the Indian refrigerator market has seen a strong trend towards larger and more consumptive frost-free units. Room air conditioners in India have traditionally been sold to commercial sector customers, but an increasing number are going to the residential sector. Room air conditioner sales growth in India peaked in the last few years at 20percent per year. In this paper, we perform an engineering-based analysis using data specific to Indian appliances. We evaluate costs and benefits to residential and commercial sector consumers from increased equipment costs and utility bill savings. The analysis finds that, while the BEE scheme presents net benefits to consumers, there remain opportunities for efficiency improvement that would optimize consumer benefits, according to Life Cycle Cost analysis. Due to the large and growing market for refrigerators and air conditioners in India, we forecast large impacts from the standards and labeling program as scheduled. By 2030, this program, if fully implemented would reduce Indian residential electricity consumption by 55 TWh. Overall savings through 2030 totals 385 TWh. Finally, while efficiency levels have been set for several years for refrigerators, labels and MEPS for these products remain voluntary. We therefore consider the negative impact of this delay of implementation to energy and financial savings achievable by 2030.

  14. Navajo Electrification Demonstration Program

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Future Plans * Navajo Electrification Demonstration Program -Video OBJECTIVES OBJECTIVES " ... Navajo Electrification Demonstration Navajo Electrification Demonstration Program Program ...

  15. PROGRAM ABSTRACTS

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    & DEVELOPMENT: PROGRAM ABSTRACTS Energy Efficiency and Renewable Energy Office of Transportation Technologies Office of Advanced Automotive Technologies Catalyst Layer Bipolar Plate Electrode Backing Layers INTEGRATED SYSTEMS Polymer Electrolyte Membrane Fuel Cells Fuel Cell Stack PEM STACK & STACK COMPONENTS Fuel Cell Stack System Air Management System Fuel Processor System For Transportation June 1999 ENERGY EFFICIENCY AND RENEWABLE ENERGY OFFICE OF TRANSPORTATION TECHNOLOGIES OFFICE

  16. Program Development

    SciTech Connect (OSTI)

    Atencio, Julian J.

    2014-05-01

    This presentation covers how to go about developing a human reliability program. In particular, it touches on conceptual thinking, raising awareness in an organization, the actions that go into developing a plan. It emphasizes evaluating all positions, eliminating positions from the pool due to mitigating factors, and keeping the process transparent. It lists components of the process and objectives in process development. It also touches on the role of leadership and the necessity for audit.

  17. Quality Program

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    QP001 Revision 0 Effective October 15, 2001 QUALITY PROGRAM Prepared by Electric Transportation Applications Prepared by: _______________________________ Date:__________ Jude M. Clark Approved by: _______________________________________________ Date: ______________ Donald B. Karner Procedure ETA-QP001 Revision 0 2 ď›™2001 Electric Transportation Applications All Rights Reserved TABLE OF CONTENTS 1.0 Objectives 3 2.0 Scope 3 3.0 Documentation 3 4.0 Prerequisites 4 5.0 Exclusions 5 6.0 Quality

  18. Method for producing labeled single-stranded nucleic acid probes

    DOE Patents [OSTI]

    Dunn, John J.; Quesada, Mark A.; Randesi, Matthew

    1999-10-19

    Disclosed is a method for the introduction of unidirectional deletions in a cloned DNA segment. More specifically, the method comprises providing a recombinant DNA construct comprising a DNA segment of interest inserted in a cloning vector, the cloning vector having an f1 endonuclease recognition sequence adjacent to the insertion site of the DNA segment of interest. The recombinant DNA construct is then contacted with the protein pII encoded by gene II of phage f1 thereby generating a single-stranded nick. The nicked DNA is then contacted with E. coli Exonuclease III thereby expanding the single-stranded nick into a single-stranded gap. The single-stranded gapped DNA is then contacted with a single-strand-specific endonuclease thereby producing a linearized DNA molecule containing a double-stranded deletion corresponding in size to the single-stranded gap. The DNA treated in this manner is then incubated with DNA ligase under conditions appropriate for ligation. Also disclosed is a method for producing single-stranded DNA probes. In this embodiment, single-stranded gapped DNA, produced as described above, is contacted with a DNA polymerase in the presence of labeled nucleotides to fill in the gap. This DNA is then linearized by digestion with a restriction enzyme which cuts outside the DNA segment of interest. The product of this digestion is then denatured to produce a labeled single-stranded nucleic acid probe.

  19. A European Sustainable Tourism Labels proposal using a composite indicator

    SciTech Connect (OSTI)

    Blancas, Francisco Javier; Lozano-Oyola, Macarena; González, Mercedes

    2015-09-15

    The tourism sector in Europe faces important challenges which it must deal with to promote its future development. In this context, the European Commission considers that two key issues must be addressed. On the one hand, a better base of socio-economic knowledge about tourism and its relationship with the environment is needed, and, on the other hand, it is necessary to improve the image of European areas as quality sustainable tourism destinations. In this paper we present analytical tools that cover these needs. Specifically, we define a system of sustainable tourism indicators and we obtain a composite indicator incorporating weights quantified using a panel of experts. Employing the values of this global indicator as a basis, we define a Sustainable Tourism Country-Brand Ranking which assesses the perception of each country-brand depending on its degree of sustainability, and a system of sustainable tourism labels which reward the management carried out. - Highlights: • We define a system of indicators to improve the knowledge about sustainable tourism. • We obtain composite indicators based on expert knowledge. • The Sustainable Tourism Country-Brand Ranking would improve the image of destinations. • We define a Sustainable Tourism Labels System to assess country-brands. • The conclusions of the empirical analysis can be extrapolated to other tourist areas.

  20. STEP Program Benchmark Report

    Broader source: Energy.gov [DOE]

    STEP Program Benchmark Report, from the Tool Kit Framework: Small Town University Energy Program (STEP).

  1. Maryland Efficiency Program Options

    Office of Energy Efficiency and Renewable Energy (EERE)

    Maryland Efficiency Program Options, from the Tool Kit Framework: Small Town University Energy Program (STEP).

  2. Connecticut launches nation’s first statewide Home Energy Score Program

    Broader source: Energy.gov [DOE]

    Connecticut recently launched a statewide residential energy labeling program that will make energy efficiency labels ubiquitous across the state. Using the Energy Department’s Home Energy Score, EnergizeCT’s Home Energy Solutions program will provide an energy efficiency score and recommend efficiency improvements to residents across the state. Similar to a vehicle’s miles-per-gallon rating, the Home Energy Score helps homeowners and homebuyers determine a home’s expected energy use. It also provides recommendations for improving energy efficiency.

  3. Program Evaluation: Program Logic | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Program Logic Program Evaluation: Program Logic Step four will help you develop a logical model for your program (learn more about the other steps in general program evaluations): What is a Logic Model? Benefits of Using Logic Modeling Pitfalls and How to Avoid Them Steps to Developing a Logic Model What is a Logic Model? Logic modeling is a thought process program evaluators have found to be useful for at least forty years and has become increasingly popular with program managers during the

  4. Preparation of 13C/15N-labeled oligomers using the polymerase chain reaction

    DOE Patents [OSTI]

    Chen, Xian; Gupta, Goutam; Bradbury, E. Morton

    2001-01-01

    Preparation of .sup.13 C/.sup.15 N-labeled DNA oligomers using the polymerase chain reaction (PCR). A PCR based method for uniform (.sup.13 C/.sup.15 N)-labeling of DNA duplexes is described. Multiple copies of a blunt-ended duplex are cloned into a plasmid, each copy containing the sequence of interest and restriction Hinc II sequences at both the 5' and 3' ends. PCR using bi-directional primers and uniformly .sup.13 C/.sup.15 N-labeled dNTP precursors generates labeled DNA duplexes containing multiple copies of the sequence of interest. Twenty-four cycles of PCR, followed by restriction and purification, gave the uniformly .sup.13 C/.sup.15 N-labeled duplex sequence with a 30% yield. Such labeled duplexes find significant applications in multinuclear magnetic resonance spectroscopy.

  5. California Homebuyers Find More Value in Energy-Efficient Labeled...

    Broader source: Energy.gov (indexed) [DOE]

    Energy Upgrade California in Los Angeles County, a Better Buildings Neighborhood Program ... Researchers at the University of California, Berkeley, and the University of California, ...

  6. EIA Energy Efficiency-Appliance Standards and Labeling Links

    U.S. Energy Information Administration (EIA) Indexed Site

    and enforcement requirements for residential appliances; final rule Energy Efficiency and Renewable Energy - Appliances & Commercial Equipment Standards, the program develops test...

  7. Bureau of Energy Efficiency Standard & Labelling (India) Website...

    Open Energy Info (EERE)

    URI: cleanenergysolutions.orgcontentbureau-energy-efficiency-standard-lab Language: English Policies: "Deployment Programs,Regulations" is not in the list of possible...

  8. Intergovernmental Programs | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Intergovernmental Programs Intergovernmental Programs Intergovernmental Programs Intergovernmental Programs Intergovernmental Programs Intergovernmental Programs Intergovernmental Programs Intergovernmental Programs Intergovernmental Programs Intergovernmental Programs Intergovernmental Programs Intergovernmental Programs Intergovernmental Programs Intergovernmental Programs The Office of Environmental Management supports, by means of grants and cooperative agreements, a number of

  9. Wind Program News

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    label-hidden">
    ...

  10. Program Update

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    April-June 2014 issue of the U.S. Department of Energy (DOE) Offce of Legacy Management (LM) Program Update. This publication is designed to provide a status of activities within LM. Please direct all comments and inquiries to lm@hq.doe.gov. April-June 2014 Visit us at http://energy.gov/lm/ Goal 4 Optimizing the Use of Federal Lands Through Disposition The foundation of the U.S. Department of Energy (DOE) Offce of Legacy Manage- ment's (LM) Goal 4, "Optimize the use of land and

  11. Program Update

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    5 issue of the U.S. Department of Energy (DOE) Offce of Legacy Management (LM) Program Update. This publication is designed to provide a status of activities within LM. Please direct all comments and inquiries to lm@hq.doe.gov. January-March 2015 Visit us at http://energy.gov/lm/ Goal 4 Successful Transition from Mound Site to Mound Business Park Continues The Mound Business Park attracts a variety of businesses to the former U.S. Department of Energy (DOE) Mound, Ohio, Site in Miamisburg. In

  12. Document clustering methods, document cluster label disambiguation methods, document clustering apparatuses, and articles of manufacture

    DOE Patents [OSTI]

    Sanfilippo, Antonio; Calapristi, Augustin J.; Crow, Vernon L.; Hetzler, Elizabeth G.; Turner, Alan E.

    2009-12-22

    Document clustering methods, document cluster label disambiguation methods, document clustering apparatuses, and articles of manufacture are described. In one aspect, a document clustering method includes providing a document set comprising a plurality of documents, providing a cluster comprising a subset of the documents of the document set, using a plurality of terms of the documents, providing a cluster label indicative of subject matter content of the documents of the cluster, wherein the cluster label comprises a plurality of word senses, and selecting one of the word senses of the cluster label.

  13. Microfluidic Technology Platforms for Synthesizing, Labeling and Measuring the Kinetics of Transport and Biochemical Reactions for Developing Molecular Imaging Probes

    SciTech Connect (OSTI)

    Phelps, Michael E.

    2009-09-01

    Radiotracer techniques are used in environmental sciences, geology, biology and medicine. Radiotracers with Positron Emission Tomography (PET) provided biological examinations of ~3 million patients 2008. Despite the success of positron labeled tracers in many sciences, there is limited access in an affordable and convenient manner to develop and use new tracers. Integrated microfluidic chips are a new technology well matched to the concentrations of tracers. Our goal is to develop microfluidic chips and new synthesis approaches to enable wide dissemination of diverse types of tracers at low cost, and to produce new generations of radiochemists for which there are many unfilled jobs. The program objectives are to: 1. Develop an integrated microfluidic platform technology for synthesizing and 18F-labeling diverse arrays of different classes of molecules. 2. Incorporate microfluidic chips into small PC controlled devices (“Synthesizer”) with a platform interfaced to PC for electronic and fluid input/out control. 3. Establish a de-centralized model with Synthesizers for discovering and producing molecular imaging probes, only requiring delivery of inexpensive [18F]fluoride ion from commercial PET radiopharmacies vs the centralized approach of cyclotron facilities synthesizing and shipping a few different types of 18F-probes. 4. Develop a position sensitive avalanche photo diode (PSAPD) camera for beta particles embedded in a microfluidic chip for imaging and measuring transport and biochemical reaction rates to valid new 18F-labeled probes in an array of cell cultures. These objectives are met within a research and educational program integrating radio-chemistry, synthetic chemistry, biochemistry, engineering and biology in the Crump Institute for Molecular Imaging. The Radiochemistry Training Program exposes PhD and post doctoral students to molecular imaging in vitro in cells and microorganisms in microfluidic chips and in vivo with PET, from new technologies

  14. Automatic Labeling for Entity Extraction in Cyber Security

    SciTech Connect (OSTI)

    Bridges, Robert A; Jones, Corinne L; Iannacone, Michael D; Testa, Kelly M; Goodall, John R

    2014-01-01

    Timely analysis of cyber-security information necessitates automated information extraction from unstructured text. While state-of-the-art extraction methods produce extremely accurate results, they require ample training data, which is generally unavailable for specialized applications, such as detecting security related entities; moreover, manual annotation of corpora is very costly and often not a viable solution. In response, we develop a very precise method to automatically label text from several data sources by leveraging related, domain-specific, structured data and provide public access to a corpus annotated with cyber-security entities. Next, we implement a Maximum Entropy Model trained with the average perceptron on a portion of our corpus (~750,000 words) and achieve near perfect precision, recall, and accuracy, with training times under 17 seconds.

  15. Geothermal Technologies Program Overview - Peer Review Program

    SciTech Connect (OSTI)

    Milliken, JoAnn

    2011-06-06

    This Geothermal Technologies Program presentation was delivered on June 6, 2011 at a Program Peer Review meeting. It contains annual budget, Recovery Act, funding opportunities, upcoming program activities, and more.

  16. Nucleic acid analysis using terminal-phosphate-labeled nucleotides

    DOE Patents [OSTI]

    Korlach, Jonas; Webb, Watt W.; Levene, Michael; Turner, Stephen; Craighead, Harold G.; Foquet, Mathieu

    2008-04-22

    The present invention is directed to a method of sequencing a target nucleic acid molecule having a plurality of bases. In its principle, the temporal order of base additions during the polymerization reaction is measured on a molecule of nucleic acid, i.e. the activity of a nucleic acid polymerizing enzyme on the template nucleic acid molecule to be sequenced is followed in real time. The sequence is deduced by identifying which base is being incorporated into the growing complementary strand of the target nucleic acid by the catalytic activity of the nucleic acid polymerizing enzyme at each step in the sequence of base additions. A polymerase on the target nucleic acid molecule complex is provided in a position suitable to move along the target nucleic acid molecule and extend the oligonucleotide primer at an active site. A plurality of labelled types of nucleotide analogs are provided proximate to the active site, with each distinguishable type of nucleotide analog being complementary to a different nucleotide in the target nucleic acid sequence. The growing nucleic acid strand is extended by using the polymerase to add a nucleotide analog to the nucleic acid strand at the active site, where the nucleotide analog being added is complementary to the nucleotide of the target nucleic acid at the active site. The nucleotide analog added to the oligonucleotide primer as a result of the polymerizing step is identified. The steps of providing labelled nucleotide analogs, polymerizing the growing nucleic acid strand, and identifying the added nucleotide analog are repeated so that the nucleic acid strand is further extended and the sequence of the target nucleic acid is determined.

  17. HEATKAU Program.

    Energy Science and Technology Software Center (OSTI)

    2013-07-24

    Version 00 Calculations of the decay heat is of great importance for the design of the shielding of discharged fuel, the design and transport of fuel-storage flasks and the management of the resulting radioactive waste. These are relevant to safety and have large economic and legislative consequences. In the HEATKAU code, a new approach has been proposed to evaluate the decay heat power after a fission burst of a fissile nuclide for short cooling time.more » This method is based on the numerical solution of coupled linear differential equations that describe decays and buildups of the minor fission products (MFPs) nuclides. HEATKAU is written entirely in the MATLAB programming environment. The MATLAB data can be stored in a standard, fast and easy-access, platform- independent binary format which is easy to visualize.« less

  18. Machinist Pipeline/Apprentice Program Program Description

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    cost effective than previous time-based programs Moves apprentices to journeyworker status more quickly Program Coordinator: Heidi Hahn Email: hahn@lanl.gov Phone number:...

  19. Existing Facilities Rebate Program

    Broader source: Energy.gov [DOE]

    The NYSERDA Existing Facilities program merges the former Peak Load Reduction and Enhanced Commercial and Industrial Performance programs. The new program offers a broad array of different...

  20. EECBG Financing Program Annual ...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Additional cost share required to administer the program Process Metrics-Underlying ... administering the Program and carrying out underlying activities supported by the Program. ...

  1. Better Buildings Neighborhood Program Business Models Guide: Program Administrator Description

    Broader source: Energy.gov [DOE]

    Better Buildings Neighborhood Program Business Models Guide: Program Administrator Business Models, Program Administrator Description.

  2. Synthesis and evaluation of radioactive and fluorescent residualizing labels for identifying sites of plasma protein catabolism

    SciTech Connect (OSTI)

    Maxwell, J.L.; Baynes, J.W.; Thorpe, S.R.

    1986-05-01

    Inulin and lactose were each coupled to tyramine by reductive amination with NaBH/sub 3/CN and the tyramine then labeled with /sup 125/I. Dilactitol-/sup 125/I-tyramine (DLT) and inulin-/sup 125/I-tyramine (InTn) were coupled by reductive amination and cyanuric chloride, respectively, to asialofetuin (ASF), fetuin and rat serum albumin (RSA). Attachment of either label had no effect on the circulating half-lives of the proteins. Radioactivity from labeled ASF was recovered in rat liver (> 90%) by 1 h post-injection and remained in liver with half-lives of 2 and 6 days, respectively, for the DLT and InTn labels. Whole body recoveries of radioactivity from DLT- and InTn labels. Whole body recoveries of radioactivity from DLT- and InTn-labeled RSA were 5 and 6.5 days, respectively, again indicating that the larger glycoconjugate label residualized more efficiently in cells following protein degradation. (Lactitol)/sub 2/-N-CH/sub 2/-CH/sub 2/-NH-fluroescein (DLF) was also coupled to ASF by reductive amination and recovered quantitatively in liver at 1 h post-injection. Native ASF was an effective competitor for clearance of DLF-ASF from the circulation. Fluorescent degradation products were retained in liver with a half-life of 1.2 days. Residualizing fluorescent labels should be useful for identification and sorting of cells active in the degradation of plasma proteins.

  3. Label-free functional nucleic acid sensors for detecting target agents

    DOE Patents [OSTI]

    Lu, Yi; Xiang, Yu

    2015-01-13

    A general methodology to design label-free fluorescent functional nucleic acid sensors using a vacant site approach and an abasic site approach is described. In one example, a method for designing label-free fluorescent functional nucleic acid sensors (e.g., those that include a DNAzyme, aptamer or aptazyme) that have a tunable dynamic range through the introduction of an abasic site (e.g., dSpacer) or a vacant site into the functional nucleic acids. Also provided is a general method for designing label-free fluorescent aptamer sensors based on the regulation of malachite green (MG) fluorescence. A general method for designing label-free fluorescent catalytic and molecular beacons (CAMBs) is also provided. The methods demonstrated here can be used to design many other label-free fluorescent sensors to detect a wide range of analytes. Sensors and methods of using the disclosed sensors are also provided.

  4. Human Reliability Program Overview

    SciTech Connect (OSTI)

    Bodin, Michael

    2012-09-25

    This presentation covers the high points of the Human Reliability Program, including certification/decertification, critical positions, due process, organizational structure, program components, personnel security, an overview of the US DOE reliability program, retirees and academia, and security program integration.

  5. Vehicle Technologies Program Overview

    SciTech Connect (OSTI)

    none,

    2006-09-05

    Overview of the Vehicle Technologies Program including external assessment and market view; internal assessment, program history and progress; program justification and federal role; program vision, mission, approach, strategic goals, outputs, and outcomes; and performance goals.

  6. Residential Buildings Integration Program

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... Program Existing Homes HUD The residential program is grounded on technology and research. ... * Quantitative (reporting) * Qualitative (account management, peer exchange ...

  7. HQ Mediation Program Brochure

    Broader source: Energy.gov [DOE]

    This document is the HQ Mediation Program's brochure.  It generally discusses the services the program offers.

  8. Utility Partnerships Program Overview

    SciTech Connect (OSTI)

    2014-10-03

    Document describes the Utility Partnerships Program within the U.S. Department of Energy's Federal Energy Management Program.

  9. STEM Education Program Inventory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Issue for STEM Education Program Inventory Title of Program* Requestor Contact Information First Name* Last Name* Phone Number* E-mail* Fax Number Institution Name Program Description* Issue Information Leading Organization* Location of Program / Event Program Address Program Website To select multiple options, press CTRL and click. Type of Program (if Other, enter information in the box to the right.)* Workforce Development Student Programs Public Engagement in Life Long Learning

  10. Machinist Pipeline/Apprentice Program Program Description

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Machinist Pipeline/Apprentice Program Program Description The Machinist Pipeline Program was created by the Prototype Fabrication Division to fill a critical need for skilled journeyworker machinists. It is based on a program developed by the National Institute for Metalworking Skills (NIMS) in conjunction with metalworking trade associations to develop and maintain a globally competitive U.S. workforce. The goal is to develop and implement apprenticeship programs that are aligned with

  11. Audit Report on "The Department's Management of the ENERGY STAR Program"

    SciTech Connect (OSTI)

    2009-10-01

    The American Recovery and Reinvestment Act (Recovery Act) authorized about $300 million in consumer rebate incentives for purchases of products rated under the 'ENERGY STAR' Program. ENERGY STAR, a voluntary labeling program established in 1992, provides consumers with energy efficiency data for a range of products so that they can make informed purchase judgments. The overall goal of the program is to encourage consumers to choose energy efficient products, advancing the nationwide goal of reducing energy consumption. The U.S. Environmental Protection Agency (EPA) managed the ENERGY STAR Program on a stand-alone basis until 1996 when it joined forces with the Department of Energy (Department). A Memorandum of Cooperation expanded the ENERGY STAR product categories, giving the Department responsibility for overseeing eight product categories such as windows, dishwashers, clothes washers, and refrigerators, while EPA retained responsibility for electronic product categories and heating, ventilating, and cooling equipment. Each agency is responsible for setting product efficiency specifications for those items under its control and for ensuring the proper use of the ENERGY STAR label in the marketplace. In August 2007, the EPA Office of Inspector General issued an audit report identifying significant control weaknesses in EPA's management of ENERGY STAR. The Department, concerned by the findings at EPA and eager to improve its own program, developed an approach to verify adherence to product specifications, ensure proper use of the ENERGY STAR label in the marketplace, and improve the establishment of product specifications. As evidenced by the commitment of $300 million in Recovery Act funds, the ENERGY STAR Program plays an important role in the U.S. efforts to reduce energy consumption. We initiated this audit to determine whether the Department had implemented the actions it announced in 2007 to strengthen the Program. The Department had not implemented planned

  12. Enhanced detection of fluorescence quenching in labeled cells

    DOE Patents [OSTI]

    Crissman, Harry A.; Steinkamp, John A.

    1992-01-01

    A method is provided for quantifying BrdU labeled DNA in cells. The BrdU is incorporated into the DNA and the DNA is stained with a first fluorochrome having a fluorescence which is quenchable by BrdU. The first fluorochrome is preferably a thymidine base halogen analogue, such as a Hoechst fluorochrome. The DNA is then stained with a second fluorochrome having a fluorescence that is substantially uneffected by BrdU. The second fluorochrome may be selected from the group consisting of mithramycin, chromomycin A3, olivomycin, propidium iodide and ethidium bromine. The fluorescence from the first and second fluorochromes is then measured to obtain first and second output signals, respectively. The first output signal is substracted from the second output signal to obtain a difference signal which is functionally related to the quantity of BrdU incorporated into DNA. The technique is particularly useful for quantifying the synthesis of DNA during the S-phase of the cell cycle.

  13. Enhanced detection of fluorescence quenching in labeled cells

    DOE Patents [OSTI]

    Crissman, H.A.; Steinkamp, J.A.

    1987-11-30

    A method is provided for quantifying BrdU labeled DNA in cells. The BrdU is substituted onto the DNA and the DNA is stained with a first fluorochrome having a fluorescence which is quenchable by BrdU. The first fluorochrome is preferably a thymidine base halogen analogue, such as a Hoechst fluorochrome. The DNA is then stained with a second fluorochrome having a fluorescence which is substantially uneffected by BrdU. The second fluorochrome may be selected from the group consisting of mithramycin, chromomycin A3, olivomycin, propidium iodide and ethidium bromine. The fluorescence from the first and second fluorochromes is then measured to obtain first and second output signals, respectively. The first output signal is subtracted from the second output signal to obtain a difference signal which is functionally related to the quantity of BrdU incorporated into DNA. The technique is particularly useful for quantifying the synthesis of DNA during the S-phase of the cell cycle. 2 figs.

  14. U.S. EPA, DOE Announce Changes to Bolster ENERGY STAR Program | Department

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of Energy EPA, DOE Announce Changes to Bolster ENERGY STAR Program U.S. EPA, DOE Announce Changes to Bolster ENERGY STAR Program April 14, 2010 - 12:00am Addthis WASHINGTON, DC - The U.S. Environmental Protection Agency and the Department of Energy today jointly announced changes to the ENERGY STAR® product certification process to ensure that only products meeting the ENERGY STAR® requirements can receive an ENERGY STAR® label. These changes accelerate steps DOE and EPA have initiated

  15. Synthesis and preliminary biological evaluations of fluorescent or 149Promethium labeled Trastuzumab-polyethylenimine

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Fitzsimmons, Jonathan; Nayak, Tapan; Cutler, Cathy; Atcher, Robert

    2015-12-30

    Radioimmunotherapy utilize a targeting antibody coupled to a therapeutic isotope to target and treat a tumor or disease. In this study we examine the synthesis and cell binding of a polymer scaffold containing a radiotherapeutic isotope and a targeting antibody. Methods: The multistep synthesis of a fluorescent or 149Promethium-labeled Trastuzumab-polyethyleneimine (PEI), Trastuzumab, or PEI is described. In vitro uptake, internalization and/or the binding affinity to the Her2/neu expressing human breast adenocarcinoma SKBr3 cells was investigated with the labeled compounds. Fluorescent-labeled Trastuzumab-PEI was internalized more into cells at 2 and 18 h than fluorescent-labeled Trastuzumab or PEI. The fluorescent-labeled Trastuzumab wasmore » concentrated on the cell surface at 2 and 18 h and the labeled PEI had minimal uptake. DOTA-PEI was prepared and contained an average of 16 chelates per PEI; the compound was radio-labeled with 149Promethium and conjugated to Trastuzumab. The purified 149Pm-DOTA-PEI-Trastuzumab had a radiochemical purity of 96.7% and a specific activity of 0.118 TBq/g. The compound demonstrated a dissociation constant for the Her2/neu receptor of 20.30 ± 6.91 nM. In conclusion, the results indicate the DOTA-PEI-Trastuzumab compound has potential as a targeted therapeutic carrier, and future in vivo studies should be performed.« less

  16. High School Internship Program

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    High School Internship Program High School Internship Program Point your career towards Los Alamos Lab: work with the best minds on the planet in an inclusive environment that is rich in intellectual vitality and opportunities for growth. Contact Program Manager Scott Robbins Student Programs (505) 667-3639 Email Program Coordinator Brenda Montoya Student Programs (505) 667-4866 Email Opportunities for Northern New Mexico high school seniors The High School Internship Program provides qualified

  17. DOE Technical Assistance Program

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Designing Effective Renewables Programs Cheryl Jenkins Vermont Energy Investment Corporation DOE Technical Assistance Program Team 4 - Program & Project Development & Implementation September 28, 2010 2 | Designing Effective Renewables Programs eere.energy.gov Webinar Overview * Technical Assistance Project (TAP) Overview * The Framework for an Effective Program * Effective Program Design Approaches * Resources * Q&A 3 | Designing Effective Renewables Programs eere.energy.gov What is

  18. Tax Credits, Rebates & Savings | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    CitySmart Energy Efficiency Program No cost direct install measures include low flow aerators, low flow pre-rinse spray valves, compact fluorescent lamps, vending misers,...

  19. State Energy Program Competitive Financial Assistance Program

    Broader source: Energy.gov [DOE]

    State Energy Program (SEP) dedicates a portion of its funding each year to provide competitively awarded financial assistance to U.S. states and territories to advance policies, programs, and market strategies.

  20. Final report-98-ERI-003 identification of population with lifetime 41Ca-labeled skeletons

    SciTech Connect (OSTI)

    Freeman, S P

    1999-02-25

    In 1997 we first postulated the existence of a special human population that had had their skeletons inadvertently isotopically adulterated in the past. We theorized that the population, and the necessary LLNL accelerator mass spectrometer (AMS) measurement technology, would prove a significant resource in the fight to combat osteoporosis. This LDRD project was to establish such. The project was significantly successful in its initial year, but was not renewed for another and the research is now ended at LLNL. We proposed a three-year program to (1) confirm the magnitude and extent of historical 41 Ca dosing, (2) exactly characterize the long-term 41 Ca signal by comparing it with conventional measurements of skeletal health, and (3) demonstrate the utility of the historically labeled population in evaluating an actual potential therapy for osteoporosis. However, rather than investigate historical records to learn the identity of those inadvertently dosed, find them, and if possible enroll them into a new protocol, this project was to be particularly efficient by making use of a multiyear archive of samples from original, inadvertent 41 Ca-dosing experiments at Creighton University in Omaha, Nebraska. Because the subjects had been dosed in conventional studies of calcium kinetics, much important correlating historical data would also be available for comparison. Measurements of contemporary urine samples specifically provided for this project by selected identified subjects would follow. We discovered a second archive at the University of Texas Southwestern Medical Center. This is potentially a better source of material as the samples were generated in numerous historical evaluations of actual osteoporosis therapies in which 41 Ca-impure radiotracers were used. The therapies might now powerfully be retrospectively evaluated, both to contribute to our understanding of the therapies and to highlight the potential of the use of 41 Ca tracer and LLNL measurement.

  1. Look at the label and indicate the type of unit for which you...

    U.S. Energy Information Administration (EIA) Indexed Site

    Department of Energy Washington, DC 20585 Case Label Here STEP 1 STEP 2 Please provide ... C O M STEP 3 Reporting format: Report the requested information on this form, or in a ...

  2. Energy Department Sets Tougher Standards for Clothes Washers to Qualify for the ENERGY STAR® Label

    Broader source: Energy.gov [DOE]

    WASHINGTON, DC - The U.S. Department of Energy (DOE) today announced tougher standards for clothes washers to qualify for the ENERGY STAR® label, which lets American families identify which clothes...

  3. Look at the label and indicate the type of unit for which you...

    U.S. Energy Information Administration (EIA) Indexed Site

    Case Label Here STEP 1 STEP 2 Please provide the following information for the person who completed this form. (Use each box for individual letters, numbers, characters, or spaces. ...

  4. DOE Withdraws the Energy Star Label from 34 Compact Fluorescent Light Bulbs

    Broader source: Energy.gov [DOE]

    Washington, DC - On January 25th, the General Counsel notified 25 manufacturers that the Department of Energy has withdrawn their right to use the Energy Star label on 34 different models of...

  5. SRNL LDRD - Program Contacts

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Program Contacts Dr. Elizabeth Hoffman LDRD Program Manager Elizabeth.Hoffman@srnl.doe.gov 803.725.5475 Nixon J. Peralta Program Manager, CEM Office of Laboratory Oversight U.S....

  6. Vehicle Technologies Program Implementation

    SciTech Connect (OSTI)

    none,

    2009-06-19

    The Vehicle Technologies Program takes a systematic approach to Program implementation. Elements of this approach include the evaluation of new technologies, competitive selection of projects and partners, review of Program and project improvement, project tracking, and portfolio management and adjustment.

  7. Y-12 Apprentice Program

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Apprentice Program Over the years Y-12 has produced numerous training programs. Many of them have been developed at Y-12 to meet special needs. The training programs have ranged...

  8. Method for rapid base sequencing in DNA and RNA with two base labeling

    DOE Patents [OSTI]

    Jett, James H.; Keller, Richard A.; Martin, John C.; Posner, Richard G.; Marrone, Babetta L.; Hammond, Mark L.; Simpson, Daniel J.

    1995-01-01

    Method for rapid-base sequencing in DNA and RNA with two-base labeling and employing fluorescent detection of single molecules at two wavelengths. Bases modified to accept fluorescent labels are used to replicate a single DNA or RNA strand to be sequenced. The bases are then sequentially cleaved from the replicated strand, excited with a chosen spectrum of electromagnetic radiation, and the fluorescence from individual, tagged bases detected in the order of cleavage from the strand.

  9. Synthesis of isotopically labeled R- or S-[.sup.13C, .sup.2H] glycerols

    DOE Patents [OSTI]

    Martinez, Rodolfo A.; Unkefer, Clifford J.; Alvarez, Marc A.

    2008-01-22

    The present invention is directed to asymmetric chiral labeled glycerols including at least one chiral atom, from one to two .sup.13C atoms and from zero to four deuterium atoms bonded directly to a carbon atom, e.g., (2S) [1,2-.sup.13C.sub.2]glycerol and (2R) [1,2-.sup.13C.sub.2]glycerol, and to the use of such chiral glycerols in the preparation of labeled amino acids.

  10. Method for rapid base sequencing in DNA and RNA with two base labeling

    DOE Patents [OSTI]

    Jett, J.H.; Keller, R.A.; Martin, J.C.; Posner, R.G.; Marrone, B.L.; Hammond, M.L.; Simpson, D.J.

    1995-04-11

    A method is described for rapid-base sequencing in DNA and RNA with two-base labeling and employing fluorescent detection of single molecules at two wavelengths. Bases modified to accept fluorescent labels are used to replicate a single DNA or RNA strand to be sequenced. The bases are then sequentially cleaved from the replicated strand, excited with a chosen spectrum of electromagnetic radiation, and the fluorescence from individual, tagged bases detected in the order of cleavage from the strand. 4 figures.

  11. Cyanine dyes with high-absorbance cross section as donor chromophores in energy transfer labels

    DOE Patents [OSTI]

    Glazer, A.N.; Mathies, R.A.; Hung, S.C.; Ju, J.

    1998-12-29

    Cyanine dyes are used as the donor fluorophore in energy transfer labels in which light energy is absorbed by a donor fluorophore and transferred to an acceptor fluorophore which responds to the transfer by emitting fluorescent light for detection. The cyanine dyes impart an unusually high sensitivity to the labels thereby improving their usefulness in a wide variety of biochemical procedures, particularly nucleic acid sequencing, nucleic acid fragment sizing, and related procedures. 22 figs.

  12. Methods of sequencing and detection using energy transfer labels with cyanine dyes as donor chromophores

    DOE Patents [OSTI]

    Glazer, Alexander N.; Mathies, Richard A.; Hung, Su-Chun; Ju, Jingyue

    2000-01-01

    Cyanine dyes are used as the donor fluorophore in energy transfer labels in which light energy is absorbed by a donor fluorophore and transferred to an acceptor fluorophore which responds to the transfer by emitting fluorescent light for detection. The cyanine dyes impart an unusually high sensitivity to the labels thereby improving their usefulness in a wide variety of biochemical procedures, particularly nucleic acid sequencing, nucleic acid fragment sizing, and related procedures.

  13. Cyanine dyes with high-absorbance cross section as donor chromophores in energy transfer labels

    DOE Patents [OSTI]

    Glazer, Alexander N.; Mathies, Richard A.; Hung, Su-Chun; Ju, Jingyue

    1998-01-01

    Cyanine dyes are used as the donor fluorophore in energy transfer labels in which light energy is absorbed by a donor fluorophore and transferred to an acceptor fluorophore which responds to the transfer by emitting fluorescent light for detection. The cyanine dyes impart an unusually high sensitivity to the labels thereby improving their usefulness in a wide variety of biochemical procedures, particularly nucleic acid sequencing, nucleic acid fragment sizing, and related procedures.

  14. California Homebuyers Find More Value in Energy-Efficient Labeled Homes |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy California Homebuyers Find More Value in Energy-Efficient Labeled Homes California Homebuyers Find More Value in Energy-Efficient Labeled Homes A photo of a house. During a time when many homeowners have seen their homes' values decrease, some encouraging data shows how investing in efficiency will boost resale value. Aside from the increased comfort and reduced utility bills that stem from home energy efficiency upgrades, homeowners who invest in energy-efficient

  15. NREL: Education Center - Programs

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Education Center Printable Version Programs NREL's Education Center in Golden, Colorado, offers a variety of program topics and experiences for students and adult groups addressing...

  16. State Energy Program Guidance

    Broader source: Energy.gov [DOE]

    The State Energy Program (SEP) has released the following guidance documents, listed chronologically below, that explain how states must report and manage SEP program funding.

  17. Beryllium Program - Hanford Site

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Site workers. Program Performance Assessments Beryllium Program inspection and corrective action documents Feedback & Suggestions A closely monitored area to submit questions,...

  18. Programming on Franklin

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Programming Programming on Franklin Compiling Codes on Franklin Cray provides a convenient set of wrapper commands which should be used in almost all cases for compiling and...

  19. Hydropower Program Technology Overview

    SciTech Connect (OSTI)

    Not Available

    2001-10-01

    New fact sheets for the DOE Office of Power Technologies (OPT) that provide technology overviews, description of DOE programs, and market potential for each OPT program area.

  20. Utility Partnerships Program Overview

    Broader source: Energy.gov (indexed) [DOE]

    Management Program (FEMP) Utility Partnerships Program fosters effective partnerships between federal agencies and their local serving utility. FEMP works to reduce the cost ...

  1. Energy Smart Grocer Program

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    New Commercial Program Development Commercial Current Promotions Industrial Federal Agriculture EnergySmart Grocer Program Close-out BPA and CLEAResult have concluded negotiations...

  2. Graduate Research Assistant Program

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... Living in Los Alamos Ombuds Program Scholarships Student Association Autobiographies Student Programs Advisory Committee (internal) 2015 Student Liaison Contact List (pdf)

  3. Undergraduate Student Program

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... Resources Living in Los Alamos Ombuds Program Scholarships Student Association Autobiographies Student Programs Advisory Committee (internal) 2015 Student Liaison Contact List

  4. Weapons Program Associate Directors

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    integration we have achieved between the various components of the program," said Bret Knapp, Principal Associate Director for Weapons Programs. "They have both done an...

  5. Fire Protection Program

    Broader source: Energy.gov [DOE]

    Department of Energy (DOE) Fire Protection Program provides published fire safety directives (orders, standards, and guidance documents), a range of oversight activities, an annual fire protection program summary.

  6. Methods for labeling .beta.-amyloid plaques and neurofibrillary tangles

    DOE Patents [OSTI]

    Barrio, Jorge R.; Petric, Andrej; Satyamurthy, Nagichettiar; Small, Gary W.; Cole, Gregory M.; Huang, Sung-Cheng

    2001-01-01

    A method for labeling .beta.-amyloid plaques and neurofibrillary tangles in vivo and in vitro, comprises contacting a compound of formula (I): ##STR1## with mammalian tissue. In formula (I), R.sub.1 is selected from the group consisting of --C(O)-alkyl, --C(O)-alkylenyl-R.sub.4, --C(O)O-alkyl, --C(O)O-alkylenyl-R.sub.4, --C.dbd.C(CN).sub.2 -alkyl, --C.dbd.C(CN).sub.2 -alkylenyl-R.sub.4 , ##STR2## R.sub.4 is a radical selected from the group consisting of alkyl, substituted alkyl, aryl and substituted aryl; R.sub.5, is a radical selected from the group consisting of --NH.sub.2, --OH, --SH, --NH-alkyl, --NHR.sub.4, --NH-alkylenyl-R.sub.4, --O-alkyl, --O-alkylenyl-R.sub.4, --S-alkyl, and --S-alkylenyl-R.sub.4 ; R.sub.6 is a radical selected from the group consisting of --CN, --COOH, --C(O)O-alkyl, --C(O)O-alkylenyl-R.sub.4, --C(O)-alkyl, --C(O)-alkylenyl-R.sub.4, --C(O)-halogen, --C(O)NH , --C(O)NH-alkyl, --C(O)NH-alkylenyl-R.sub.4 ; R.sub.7 is a radical selected from the group consisting of O, NH, and S; and R.sub.8 is N, O or S. R.sub.2 and R.sub.3 are each independently selected from the group consisting of alkyl and alkylenyl-R.sub.10, wherein R.sub.10 is selected from the group consisting of --OH, --OTs, halogen, spiperone, spiperone ketal and spiperone-3-yl. Alternatively, R.sub.2 and R.sub.3 together form a heterocyclic ring, optionally substituted with at least one radical selected from the group consisting of alkyl, alkoxy, OH, OTs, halogen, alkylenyl-R.sub.10, carbonyl, spiperone, spiperone ketal and spiperone-3-yl. In the compounds of formula (I), one or more of the hydrogen, halogen or carbon atoms can, optionally, be replaced with a radiolabel.

  7. Methods for labeling .beta.-amyloid plaques and neurofibrillary tangles

    DOE Patents [OSTI]

    Barrio, Jorge R.; Petric, Andrej; Satyamurthy, Nagichettiar; Small, Gary W.; Cole, Gregory M.; Huang, Sung-Cheng

    2003-12-09

    A method for labeling .beta.-amyloid plaques and neurofibrillary tangles in vivo and in vitro, comprises contacting a compound of formula (I): ##STR1## with mammalian tissue. In formula (I), R.sub.1 is selected from the group consisting of --C(O)-alkyl, --C(O)-alkylenyl-R.sub.4, --C(O)O-alkyl, --C(O)O-alkylenyl-R.sub.4, --C.dbd.C(CN).sub.2 -alkyl, --C.dbd.C(CN).sub.2 -alkylenyl-R.sub.4, ##STR2## R.sub.4 is a radical selected from the group consisting of alkyl, substituted alkyl, aryl and substituted aryl; R.sub.5 is a radical selected from the group consisting of --NH.sub.2, --OH, --SH, --NH-alkyl, --NHR.sub.4, --NH-alkylenyl-R.sub.4, --O-alkyl, --O-alkylenyl-R.sub.4, --S-alkyl, and --S-alkylenyl-R.sub.4 ; R.sub.6 is a radical selected from the group consisting of --CN, --COOH, --C(O)O-alkyl, --C(O)O-alkylenyl-R.sub.4, --C(O)-alkyl, --C(O)-alkylenyl-R.sub.4, --C(O)-halogen, --C(O)NH, --C(O)NH-alkyl, --C(O)NH-alkylenyl-R.sub.4 ; R.sub.7 is a radical selected from the group consisting of O, NH, and S; and R.sub.8 is N, O or S. R.sub.2 and R.sub.3 are each independently selected from the group consisting of alkyl and alkylenyl-R.sub.10, wherein R.sub.10 is selected from the group consisting of --OH, --OTs, halogen, spiperone, spiperone ketal and spiperone-3-yl. Alternatively, R.sub.2 and R.sub.3 together form a heterocyclic ring, optionally substituted with at least one radical selected from the group consisting of alkyl, alkoxy, OH, OTs, halogen, alkylenyl-R.sub.10, carbonyl, spiperone, spiperone ketal and spiperone-3-yl. In the compounds of formula (I), one or more of the hydrogen, halogen or carbon atoms can, optionally, be replaced with a radiolabel.

  8. Compositions for labeling .beta.-amyloid plaques and neurofibrillary tangles

    DOE Patents [OSTI]

    Barrio, Jorge R.; Petric, Andrej; Satyamurthy, Nagichettiar; Small, Gary W.; Cole, Gregory M.; Huang, Sung-Cheng

    2008-03-11

    Compositions useful for labeling .beta.-amyloid plaques and neurofibrillary tangles are provided. The compositions comprises compounds of formula (I): ##STR00001## wherein R.sub.1 is selected from the group consisting of --C(O)-alkyl, --C(O)-alkylenyl-R.sub.4, --C(O)O-alkyl, --C(O)O-alkylenyl-R.sub.4, --C.dbd.C(CN).sub.2-alkyl, --C.dbd.C(CN).sub.2-alkylenyl-R.sub.4, ##STR00002## wherein R.sub.4 is a radical selected from the group consisting of alkyl, substituted alkyl, aryl and substituted aryl; R.sub.5 is a radical selected from the group consisting of --NH.sub.2, --OH, --SH, --NH-alkyl, --NHR.sub.4, --NH-alkylenyl-R.sub.4, --O-alkyl, --O-alkylenyl-R.sub.4, --S-alkyl, and --S-alkylenyl-R.sub.4; R.sub.6 is a radical selected from the group consisting of --CN, --COOH, --C(O)O-alkyl, --C(O)O-alkylenyl-R.sub.4, --C(O)-alkyl, --C(O)-alkylenyl-R.sub.4, --C(O)-halogen, --C(O)NH-alkyl, --C(O)NH-alkylenyl-R.sub.4 and --C(O)NH.sub.2; R.sub.7 is a radical selected from the group consisting of O, NH, and S; and R.sub.8 is N, O or S; and R.sub.2 is selected from the group consisting of alkyl and alkylenyl-R.sub.10 and R.sub.3 is alkylenyl-R.sub.10, wherein R.sub.10 is selected from the group consisting of --OH, --OTs, halogen, spiperone, spiperone ketal, and spiperone-3-yl, or R.sub.2 and R.sub.3 together form a heterocyclic ring, optionally substituted with at least one radical selected from the group consisting of alkyl, alkoxy, OH, OTs, halogen, alkyl-R.sub.10, carbonyl, spiperone, spiperone ketal and spiperone-3-yl, and further wherein one or more of the hydrogen, halogen or carbon atoms are optionally replaced with a radiolabel.

  9. Assistance Program, State Energy Program, Energy Efficiency and...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Assistance Program, State Energy Program, Energy Efficiency and Conservation Block Grants Assistance Program, State Energy Program, Energy Efficiency and Conservation Block Grants ...

  10. Program Assignments | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Balanced Scorecard Program Officer Contractual Services Budget Officer Headquarters Purchase Card Program Headquarters Contract Closeout Headquarters Data Mining Programs Strategic ...

  11. Voluntary Protection Program | National Nuclear Security Administration

    National Nuclear Security Administration (NNSA)

    Voluntary Protection Program

  12. Internship Programs Calendar | The Ames Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Internship Programs Calendar

  13. Biomass Program Overview

    SciTech Connect (OSTI)

    2010-01-01

    This document provides an overview of the Biomass Program's mission, strategic goals, and research approach.

  14. ARM - Program Fact Sheets

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    MaterialsProgram Fact Sheets Publications Journal Articles Conference Documents Program Documents & Technical Reports Publications Database Public Information Materials Image Library Videos Publication Resources Submit a Publication Publishing Procedures Acronyms Glossary Logos Contacts RSS for Publications Information Materials Annual Reports Program Fact Sheets Campaign Backgrounders Education and Outreach Posters Brochures Research Highlights Summaries Program Fact Sheets Please contact

  15. Better Buildings Neighborhood Program

    Broader source: Energy.gov [DOE]

    U.S. Department of Energy Better Buildings Neighborhood Program: Business Models Guide, October 27, 2011.

  16. Laser Programs Highlights 1998

    SciTech Connect (OSTI)

    Lowdermilk, H.; Cassady, C.

    1999-12-01

    This report covers the following topics: Commentary; Laser Programs; Inertial Confinement Fusion/National Ignition Facility (ICF/NIF); Atomic Vapor Laser Isotope Separation (AVLIS); Laser Science and Technology (LS&T); Information Science and Technology Program (IS&T); Strategic Materials Applications Program (SMAP); Medical Technology Program (MTP) and Awards.

  17. Regional Energy Efficiency Programs

    Broader source: Energy.gov [DOE]

    This presentation covers regional industrial energy efficiency programs in the Midwest, Southeast, and Southwest.

  18. Light water reactor program

    SciTech Connect (OSTI)

    Franks, S.M.

    1994-12-31

    The US Department of Energy`s Light Water Reactor Program is outlined. The scope of the program consists of: design certification of evolutionary plants; design, development, and design certification of simplified passive plants; first-of-a-kind engineering to achieve commercial standardization; plant lifetime improvement; and advanced reactor severe accident program. These program activities of the Office of Nuclear Energy are discussed.

  19. SEP Program Planning Template ("Program Planning Template") ...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    File Program Planning Template More Documents & Publications Commute Mode Switching Impact Tool Energy Intensity Indicators Data Refrigerator-Freezers (multiple defrost waiver)...

  20. State Energy Program & Weatherization Assistance Program: Update

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Breakdown 6 Cumulative Spending: As of March 5, 2012: * ... programs across the broad segment of state's public building portfolio to achieve significant energy and cost savings. ...

  1. Clean Coal Technology Programs: Program Update 2007

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Includes Clean Coal Technology Demonstration Program (CCTDP), Power Plant Improvement Initiative (PPII), and Clean ... Control on Three 90-MW Coal-Fired Boilers CCPI-1 Wisconsin ...

  2. Program Year 2008 State Energy Program Formula | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Program Year 2008 State Energy Program Formula Program Year 2008 State Energy Program Formula U.S. Department of Energy (DOE) State Energy Program (SEP), SEP Program Guidance Fiscal Year 2008, Program Year 2008, energy efficiency and renewable energy programs in the states, DOE Office of Energy Efficiency and Renewable Energy fy08_grant_guidance.pdf (65.88 KB) More Documents & Publications State Energy Program Operations Manual State Energy Program Formula Grant Guidance Program Year 2007

  3. Geothermal Technologies Program Overview

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Jay Nathwani Acting Program Manager Geothermal Technologies Program Office of Energy Efficiency and Renewable Energy The Geothermal Technologies Program Overview May 18 2010 Energy Efficiency & Renewable Energy eere.energy.gov Geothermal Technologies Program (GTP) Program Topic Areas *Low Temperature, Geopressured and Coproduced Resources *Innovative Exploration Technologies National Goals *Economy Putting people to work in the near- term, and in the future *Security Developing and expanding

  4. Technology Commercialization Program 1991

    SciTech Connect (OSTI)

    Not Available

    1991-11-01

    This reference compilation describes the Technology Commercialization Program of the Department of Energy, Defense Programs. The compilation consists of two sections. Section 1, Plans and Procedures, describes the plans and procedures of the Defense Programs Technology Commercialization Program. The second section, Legislation and Policy, identifies legislation and policy related to the Program. The procedures for implementing statutory and regulatory requirements are evolving with time. This document will be periodically updated to reflect changes and new material.

  5. LDRD Program Plan master

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Laboratory-Directed Research and Development Program FY2016 Program Plan Thomas Jefferson National Accelerator Facility Newport News, Virginia Thomas Jefferson National Accelerator Facility Laboratory-Directed Research and Development Program FY2016 Program Plan Introduction The Thomas Jefferson National Accelerator Facility (Jefferson Lab) Laboratory- Directed Research and Development (LDRD) program was planned through a formal management process consistent with DOE Order 413.2B, including

  6. LANSCE | Users | User Program

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    LANSCE User Program LANSCE's User Program ensures the research it oversees represents the cutting edge of nuclear and materials science and technology. The User Program plays a key role in training the next generation of top scientists, attracting the best graduate students, postdoctoral researchers, and early-career scientists (defined as those less than 40-years old). The User Program typically begins with the first call for proposals and run until the end of the run-cycle. The User-Program

  7. An operational health physics quality assurance program

    SciTech Connect (OSTI)

    Costigan, S.A.; McAtee, J.L. III; Somers, W.M.; Huchton, R.L.

    1996-06-01

    DOE Order 5700.6C, Quality Assurance, stipulates QA requirements for all DOE activities. This order is now codified as 10CFR830.120, Nuclear Safety Management, Quality Assurance Requirements, which is applicable to DOE nuclear facilities. A Quality Assurance Management Plan (QAMP) was developed by the Health Physics Operations Group (ESH-1) at Los Alamos National Laboratory (LANL). The goal of the ESH-1 QAMP is to ensure that operational radiation protection activities meet the criteria outlined in DOE Order 5700.6C, DOE-ER-STD-6001-92 and 10CFR830.120. The ten required elements are QA Program, Personal Training and Qualifications, Quality Improvement, Documents and Records, Work Processes, Design, Procurement, Inspection and Acceptance Testing, Management Assessment and Independent Assessment. The QAMP has been useful for the development of QAMPs at nuclear facilities and has helped ensure uniformity of institutional requirements where Health Physics services are deployed to facilities. To implement a subset of QAMP requirements, a Quality Assurance Self-Evaluation Program (QASE) was established. This program provides a novel self-audit mechanism for the formal identification and correction of non-conforming items related to Operational Health Physics. Additionally, the QASE is a useful management tool for Radiological Control Technician Supervisors and staff and provides a tracking mechanism for ongoing problem areas. Data have been Collected for two calendar years on a number of concerns that fall into four general categories: radiological posting and labeling, instrumentation, monitoring requirements, and radiological documents/records.

  8. Comparison of doubly labeled water with respirometry at low- and high-activity levels

    SciTech Connect (OSTI)

    Westerterp, K.R.; Brouns, F.; Saris, W.H.; ten Hoor, F.

    1988-07-01

    In previous studies the doubly labeled water method for measuring energy expenditure in free-living humans has been validated against respirometry under sedentary conditions. In the present investigation, energy expenditure is measured simultaneously with doubly labeled water and respirometry at low- and high-activity levels. Over 6 days, five subjects were measured doing mainly sedentary activities like desk work; their average daily metabolic rate was 1.40 +/- 0.09 (SD) times sleeping metabolic rate. Four subjects were measured twice over 3.5 days, including 2 days with heavy bicycle ergometer work, resulting in an average daily metabolic rate of 2.61 +/- 0.25 (SD) times sleeping metabolic rate. At the low-activity level, energy expenditures from the doubly labeled water method were on the average 1.4 +/- 3.9% (SD) larger than those from respirometry. At the high-activity level, the doubly labeled water method yielded values that were 1.0 +/- 7.0% (SD) lower than those from respirometry. Results demonstrate the utility of the doubly labeled water method for the determination of energy expenditure in the range of activity levels in daily life.

  9. Program Launch Letter from Mayor

    Broader source: Energy.gov [DOE]

    Program Launch Letter from Mayor, from the Tool Kit Framework: Small Town University Energy Program (STEP).

  10. program | netl.doe.gov

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Program Fact Sheets Crosscutting Technology Research Program Crosscutting Technology Research Program Sensors & Controls Summary Crosscutting Technology Research Program Simulation-Based Engineering Summary Crosscutting Technology Research Program Water Management R&D Summary Crosscutting Technology Research Program Innovative Energy Concepts Summary Crosscutting Technology Research Program High Performance Materials Summary Crosscutting Technology Research Program High Performance