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Sample records for kyu taek cho

  1. Thermally Stable Gel Polymer Electrolytes Min-Kyu Song,a

    E-Print Network [OSTI]

    Popov, Branko N.

    Thermally Stable Gel Polymer Electrolytes Min-Kyu Song,a Young-Taek Kim,a Yong Tae Kim,b Byung Won/polyvinylidene fluoride PEGDA/PVdF blend gel polymer electrolytes, low molecular weight (M 742) liquid PEGDA oligomer was mixed with PVdF-HFP dissolved in ethylene carbonate/dimethyl carbonate/LiPF6 liquid electrolytes

  2. Probing water transport in polymer electrolyte fuel cells with neutron radiography

    E-Print Network [OSTI]

    Mench, Matthew M.

    Probing water transport in polymer electrolyte fuel cells with neutron radiography Kyu Taek Cho a freezing [57]. Cho et al. [6] observed no performance degradation after freeze/thaw cycling when the cell no performance loss and no damage to the CL after 20 freeze/thaw cycles in a cell purged with RH 58% gas. Several

  3. Tunable attractive and repulsive interactions between pH-responsive Jae Kyu Cho,a

    E-Print Network [OSTI]

    Breedveld, Victor

    suspensions, and enhanced thermal stability of pNIPAm-co-AAc colloidal crystals at temperatures well above in concentrated suspensions. Colloidal suspensions display various phases and microscopic struc- tures, rangingNIPAm-co- AAc) colloidal microgels as a function of pH, as determined through OrnsteinZernike analysis

  4. 20-Stage Pipelined ADC with Radix-Based Calibration Chong Kyu Yun

    E-Print Network [OSTI]

    Moon, Un-Ku

    20-Stage Pipelined ADC with Radix-Based Calibration by Chong Kyu Yun A THESIS submitted to Oregon comments on the pipelined ADC as well as a wide range of subjects in the analog field. Thanks to Dong......................................................................................................1 2. PIPELINED ARCHITECTURE

  5. Automorphic correction of the hyperbolic Kac-Moody algebra E10 Henry H. Kim and Kyu-Hwan Lee

    E-Print Network [OSTI]

    Lee, Kyu-Hwan J.

    Automorphic correction of the hyperbolic Kac-Moody algebra E10 Henry H. Kim and Kyu-Hwan Lee://jmp.aip.org/about/about_the_journal Top downloads: http://jmp.aip.org/features/most_downloaded Information for Authors: http-Moody algebra E10 Henry H. Kim1,a) and Kyu-Hwan Lee2,b) 1 Department of Mathematics, University of Toronto

  6. Kinetics of intramolecular carbon atom exchange in ketene Edward R. Lovejoy, Sang Kyu Kim, Ram6n A. Alvarez, and C. Bradley Moore

    E-Print Network [OSTI]

    Kim, Sang Kyu

    Kinetics of intramolecular carbon atom exchange in ketene Edward R. Lovejoy, Sang Kyu Kim, Ram6n A set of experiments, jet-cooled ketene 13C isotopomers were excited with tunable near-UV radiation

  7. Supersonic Jet Spectroscopic Study of p-Methoxybenzyl Alcohol Min-Chul Yoon, Sun Jong Baek, Hyeongjin Cho, Young S. Choi, and Sang Kyu Kim*

    E-Print Network [OSTI]

    Kim, Sang Kyu

    Supersonic Jet Spectroscopic Study of p-Methoxybenzyl Alcohol Min-Chul Yoon, Sun Jong Baek0 excitation spectra of p-methoxybenzyl alcohol in a supersonic jet are reported. The long in the jet. The torsional barrier height of 316 cm-1 in the S1 ground-vibrational state is obtained from

  8. Nanopores of carbon nanotubes as practical hydrogen storage media Sang Soo Han, Hyun Seok Kim, Kyu Sung Han, Jai Young Lee,

    E-Print Network [OSTI]

    Goddard III, William A.

    Nanopores of carbon nanotubes as practical hydrogen storage media Sang Soo Han, Hyun Seok Kim, Kyu walls that do not provide sites for hydrogen storage under ambient conditions. However, after treating nanopores in MWCNTs offer a promising route to hydrogen storage media for onboard practical applications

  9. Frontiers in Web Data Management Junghoo "John" Cho

    E-Print Network [OSTI]

    Cho, Junghoo "John"

    will be available for later access. Information bias: As the Web becomes the primary source information for many, CA 90095 cho@cs.ucla.edu Abstract In the last decade, the Web has become a primary source significant time and efforts looking for similar information from other sources on the Web, or it may be even

  10. State Complexity of Inversion Operations Da-Jung Cho1

    E-Print Network [OSTI]

    Han, Yo-Sub

    ] investigated the state complexity for basic operations. Later, Yu and his co-authors [7, 8, 20, 21] initi- ated] investigated a generative mechanism based on some operations inspired by mutations in genomes such as deletionState Complexity of Inversion Operations Da-Jung Cho1 , Yo-Sub Han1 , Sang-Ki Ko1 , and Kai Salomaa

  11. Understanding Pollution Dynamics in P2P File Sharing , Junghoo Cho

    E-Print Network [OSTI]

    Cho, Junghoo "John"

    Understanding Pollution Dynamics in P2P File Sharing Uichin Lee , Min Choi , Junghoo Cho , M. Y,cho,medy,gerla}@cs.ucla.edu, min@kaist.ac.kr ABSTRACT Pollution in P2P file sharing occurs when a large number of decoy files that pollution dynamics are closely related to user behavior. Therefore, we first conduct a human subject study

  12. Cho decomposition of electrically charged one-half monopole

    SciTech Connect (OSTI)

    Ng, Ban-Loong; Teh, Rosy; Wong, Khai-Ming

    2014-03-05

    Recently we have carried out some work on the Cho decomposition of the electrically neutral, finite energy one-half monopole solution of the SU(2) Yang-Mills-Higgs field theory. In this paper, we performed the decomposition of the electrically charged solution using the same numerical procedure. The gauge potential of the one-half dyon solution is decomposed into Abelian and non-Abelian components. The semi-infinite string singularity in the gauge potential is a contribution of the Higgs field and hence topological in nature. The string singularity cannot be cancelled by the non-Abelian components of the gauge potential. However, the string singularity is integrable and the energy of the solution is finite. By decomposing the magnetic fields and covariant derivatives of the Higgs field into three isospin space directions, we are able to provide conclusive evidence that the constructed one-half dyon is certainly a non-BPS solution even in the limit of vanishing Higgs self-coupling constant and electric charge. Furthermore, we found that the time component of gauge function is parallel to the Higgs field in isospace only at large distances, elsewhere they are non-parallel.

  13. 4296 Phys. Chem. Chem. Phys., 2012, 14, 42964302 This journal is c the Owner Societies 2012 Cite this: Phys. Chem. Chem. Phys., 2012, 14, 42964302

    E-Print Network [OSTI]

    Mench, Matthew M.

    in polymer electrolyte fuel cells with hydrogen deuterium contrast neutron radiography Kyu Taek Choa management in polymer electrolyte fuel cells (PEFCs) is of pivotal importance for performance and durability ranging from 5 to 30 wt% are impreg- nated into DM pores to alter water wettability to mitigate flooding

  14. Active hypothermic growth : a novel means for increasing total recombinant protein production by CHO cells

    E-Print Network [OSTI]

    Fox, Stephen Richard

    2005-01-01

    Recombinant human glycoproteins produced by Chinese Hamster Ovary (CHO) cells are an important class of therapeutic molecules and investigating means of improving the production rate and product quality of these glycoproteins ...

  15. Trch rt t ng vn phm LTAG cho ting Vit L Hng Phng1

    E-Print Network [OSTI]

    Paris-Sud XI, Universit de

    Trch rt t ng vn phm LTAG cho ting Vit L Hng Phng1 , Nguyn Th Minh Huyn1 , Nguyn Phng Thi1 t ng LTAG t kho vn bn gn nhn c php (treebank). Chng ti trnh by kt qu trch rt mt vn phm LTAG cho ting Vit. Chng trnh trch rt t ng cc vn phm LTAG c lp vi ngn ng v c phn phi di dng m ngun m

  16. C-H..O Hydrogen Bonds in Minor Groove of A-tracts in DNA Double Helices

    E-Print Network [OSTI]

    Bansal, Manju

    C-H..O Hydrogen Bonds in Minor Groove of A-tracts in DNA Double Helices Anirban Ghosh and Manju-pair as well as cross-strand C-H..O hydrogen bonds in the minor groove. The C2-H2..O2 hydrogen bonds within leads to a narrow minor groove in these regions. # 1999 Academic Press Keywords: C-H..O hydrogen bonds

  17. Dynamic isotope effect on the product energy partitioning in CH2OH ~CHO H2

    E-Print Network [OSTI]

    Kim, Myung Soo

    Dynamic isotope effect on the product energy partitioning in CH2OH ~CHO H2 Young Min Rheea March 1998; accepted 1 July 1998 The deuterium isotope effect on the product energy partitioning. Close inspection of the potential energy surface revealed that the isotope effect on KER and the product

  18. Japan, France Vying for Korea's Nuclear Project By Cho Jin-seo

    E-Print Network [OSTI]

    Japan, France Vying for Korea's Nuclear Project By Cho Jin-seo Staff Reporter France and Japan. Haignere promised privileges in fusion energy businesses and supports for Korea's own fusion energy December but didn't express its official stand so far. Fusion is a relatively safe, clean and sustainable

  19. Deblurring Low-light Images with Light Streaks Sunghyun Cho2

    E-Print Network [OSTI]

    Yang, Ming-Hsuan

    Deblurring Low-light Images with Light Streaks Zhe Hu1 Sunghyun Cho2 Jue Wang2 Ming-Hsuan Yang1 1 University of California, Merced 2 Adobe Research Abstract Images taken in low-light conditions with handheld been made recently on image deblurring, state-of-the-art approaches often fail on low-light images

  20. Demo Abstract: Energy Transference for Sensornets Affan A. Syed Young Cho John Heidemann

    E-Print Network [OSTI]

    Heidemann, John

    Demo Abstract: Energy Transference for Sensornets Affan A. Syed Young Cho John Heidemann USC continuous monitoring, 24x7, at remote, inaccessible locations making energy man- agement a critical part of most sensornets. The sensornet research community has explored energy conservation and energy

  1. Has Internet Delay Gotten Better or Worse? DK Lee, Kenjiro Cho

    E-Print Network [OSTI]

    Moon, Sue B.

    Has Internet Delay Gotten Better or Worse? DK Lee, Kenjiro Cho , Gianluca Iannaccone , and Sue@iijlab.net, gianluca.iannaccone@intel.com ABSTRACT Delay is a key Internet performance metric and its stability, vari the Internet-wide delay distribution. In order to build a representative sample set for the Internet-wide de

  2. Wind buffeting effects on the Gemini 8m primary mirrors M. K. Cho1,2

    E-Print Network [OSTI]

    Wind buffeting effects on the Gemini 8m primary mirrors M. K. Cho1,2 , L. Stepp1 , and S. Kim3 and Mechanical Engineering, University of Arizona, 1130 N. Mountain, Tucson, AZ 85721 #12;Wind buffeting effects mirror distortion caused by wind pressure variations. To quantify telescope wind loading effects

  3. Cho-Duan-Ge decomposition of QCD in the constraintless Clairaut-type formalism

    E-Print Network [OSTI]

    Michael L. Walker; Steven Duplij

    2015-03-15

    We apply the recently derived constraintless Clairaut-type formalism to the Cho-Duan-Ge decomposition in SU(2) QCD. We find nontrivial corrections to the physical equations of motion and that the contribution of the topological degrees of freedom is qualitatively different from that found by treating the monopole potential as though it were dynamic. We also find alterations to the field commutation relations that undermine the particle interpretation in the presence of the chromomonopole condensate.

  4. {solusea, sbcho}@cs.yonsei.ac.kr Hyeun-Jeong Min and Sung-Bae Cho

    E-Print Network [OSTI]

    Cho, Sung-Bae

    , sbcho}@cs.yonsei.ac.kr Hyeun-Jeong Min and Sung-Bae Cho Dept. of Computer Science, Yonsei University_Left NT_Stick_Right Stick_Right NT_Circle_Left Circle_Left NT_Circle_Right Circle_Right NT_Square_Left Square_Left NT_Square_Right Square_Right Waiting Following AvoidLeft FindTarget AvoidRight , . Q

  5. Deep Packet Filter with Dedicated Logic and Read Only Memories Young H. Cho and William H. Mangione-Smith

    E-Print Network [OSTI]

    Cho, Young Hyun

    Deep Packet Filter with Dedicated Logic and Read Only Memories Young H. Cho and William H. Mangione is a computationally expensive task. The speed of the search pattern module determines the overall performance of deep of deep packet filters to detect application level attacks in the packet payloads. Deep packet filters

  6. Test Set Reordering Using the Gate Exhaustive Test Metric Kyoung Youn Cho and Edward J. McCluskey

    E-Print Network [OSTI]

    Stanford University

    Test Set Reordering Using the Gate Exhaustive Test Metric Kyoung Youn Cho and Edward J. Mc kycho@crc.stanford.edu Abstract When a test set size is larger than desired, some patterns must be dropped. This paper presents a systematic method to reduce test set size; the method reorders a test set

  7. Instant Profiling: Instrumentation Sampling for Profiling Datacenter Applications

    E-Print Network [OSTI]

    Cortes, Corinna

    Instant Profiling: Instrumentation Sampling for Profiling Datacenter Applications Hyoun Kyu Cho Profile-guided optimization possesses huge potential to save costs for datacenters. Hardware performance programmers find code regions to optimize by monitoring datacenter applications continuously on live traffic

  8. Coordinate amplification of metallothionein I and II gene sequences in cadmium-resistant CHO variants

    SciTech Connect (OSTI)

    Hildebrand, C.E.; Crawford, B.D.; Enger, M.D.

    1983-01-01

    Cadmium-resistanc (Cd/sup r/) variants of the Chinese hamster cell line, CHO, have been derived by stepwise selection for growth in medium containing CdCl/sub 2/. These variants show coordinately increased production of both metallothionein (MT) I and II and were stably resistant to Cd/sup 2 +/ in the absence of continued selection. Genomic DNAs from these Cd/sup r/ sublines were analyzed for both MT gene copy number and MT gene organization, using cDNA sequence probes specific for each of the two Chinese hamster isometallothioneins. These analyses revealed coordinate amplification of MT I and II genes in all Cd/sup r/ variants which had increased copies of MT-encoding sequences. In situ hybridization of an MT-encoding probe to mitotic chromosomes of a Cd/sup r/ variant, which has amplified MT genes at least 14-fold, revealed a single chromosomal site of hybridization. These results suggest that the isoMTs constitute a functionally related gene cluster which amplifies coordinately in response to toxic metal stress.

  9. Barrierless proton transfer across weak CH?O hydrogen bonds in dimethyl ether dimer

    SciTech Connect (OSTI)

    Yoder, Bruce L. West, Adam H. C.; Signorell, Ruth; Bravaya, Ksenia B.; Bodi, Andras; Sztray, Blint

    2015-03-21

    We present a combined computational and threshold photoelectron photoion coincidence study of two isotopologues of dimethyl ether, (DME ? h{sub 6}){sub n} and (DME ? d{sub 6}){sub n}n = 1 and 2, in the 914 eV photon energy range. Multiple isomers of neutral dimethyl ether dimer were considered, all of which may be present, and exhibited varying CH?O interactions. Results from electronic structure calculations predict that all of them undergo barrierless proton transfer upon photoionization to the ground electronic state of the cation. In fact, all neutral isomers were found to relax to the same radical cation structure. The lowest energy dissociative photoionization channel of the dimer leads to CH{sub 3}OHCH{sub 3}{sup +} by the loss of CH{sub 2}OCH{sub 3} with a 0 K appearance energy of 9.71 0.03 eV and 9.73 0.03 eV for (DME ? h{sub 6}){sub 2} and deuterated (DME ? d{sub 6}){sub 2}, respectively. The ground state threshold photoelectron spectrum band of the dimethyl ether dimer is broad and exhibits no vibrational structure. Dimerization results in a 350 meV decrease of the valence band appearance energy, a 140 meV decrease of the band maximum, thus an almost twofold increase in the ground state band width, compared with DME ? d{sub 6} monomer.

  10. Effect of continuous irradiation on proliferation of CHO-K1 and xrs-6 cells under low and high oxygen conditions

    E-Print Network [OSTI]

    Vu, An T

    2009-01-01

    The goals of this research were to determine: 1) the effect of continuous irradiation on Chinese Hamster Ovary cells, CHO-K1 (wild type) and xrs-6 cells (mutant), and 2) the effect of continuous irradiation under low (5%) ...

  11. Thermal decomposition of CH{sub 3}CHO studied by matrix infrared spectroscopy and photoionization mass spectroscopy

    SciTech Connect (OSTI)

    Vasiliou, AnGayle K. [Department of Chemistry and Biochemistry, University of Colorado, Boulder, Colorado 80309-0215 (United States); National Renewable Energy Laboratory, 1617 Cole Blvd., Golden, Colorado 80401 (United States); Piech, Krzysztof M.; Reed, Beth; Ellison, G. Barney [Department of Chemistry and Biochemistry, University of Colorado, Boulder, Colorado 80309-0215 (United States); Zhang Xu [Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive, Pasadena, California 91109-8099 (United States); Nimlos, Mark R. [National Renewable Energy Laboratory, 1617 Cole Blvd., Golden, Colorado 80401 (United States); Ahmed, Musahid; Golan, Amir; Kostko, Oleg [Chemical Sciences Division, LBNL MS 6R-2100, Berkeley, California 94720 (United States); Osborn, David L. [Combustion Research Facility, Sandia National Laboratories, P.O. Box 969 MS 9055, Livermore, California 94551-0969 (United States); David, Donald E. [Integrated Instrument Design Facility, CIRES, University of Colorado, Boulder, Colorado 80309-0216 (United States); Urness, Kimberly N.; Daily, John W. [Center for Combustion and Environmental Research, Department of Mechanical Engineering, University of Colorado at Boulder, Boulder, Colorado 80309-0427 (United States); Stanton, John F. [Institute for Theoretical Chemistry, Department of Chemistry, University of Texas, Austin, Texas 78712 (United States)

    2012-10-28

    A heated SiC microtubular reactor has been used to decompose acetaldehyde and its isotopomers (CH{sub 3}CDO, CD{sub 3}CHO, and CD{sub 3}CDO). The pyrolysis experiments are carried out by passing a dilute mixture of acetaldehyde (roughly 0.1%-1%) entrained in a stream of a buffer gas (either He or Ar) through a heated SiC reactor that is 2-3 cm long and 1 mm in diameter. Typical pressures in the reactor are 50-200 Torr with the SiC tube wall temperature in the range 1200-1900 K. Characteristic residence times in the reactor are 50-200 {mu}s after which the gas mixture emerges as a skimmed molecular beam at a pressure of approximately 10 {mu}Torr. The reactor has been modified so that both pulsed and continuous modes can be studied, and results from both flow regimes are presented. Using various detection methods (Fourier transform infrared spectroscopy and both fixed wavelength and tunable synchrotron radiation photoionization mass spectrometry), a number of products formed at early pyrolysis times (roughly 100-200 {mu}s) are identified: H, H{sub 2}, CH{sub 3}, CO, CH{sub 2}=CHOH, HC{identical_to}CH, H{sub 2}O, and CH{sub 2}=C=O; trace quantities of other species are also observed in some of the experiments. Pyrolysis of rare isotopomers of acetaldehyde produces characteristic isotopic signatures in the reaction products, which offers insight into reaction mechanisms that occur in the reactor. In particular, while the principal unimolecular processes appear to be radical decomposition CH{sub 3}CHO (+M) {yields} CH{sub 3}+ H + CO and isomerization of acetaldehyde to vinyl alcohol, it appears that the CH{sub 2}CO and HCCH are formed (perhaps exclusively) by bimolecular reactions, especially those involving hydrogen atom attacks.

  12. Surface Plasma Treatment of Polyimide Film for Cu Metallization Sang-Jin Cho, Jin-Woo Choi, In-Seob Bae, Trieu Nguyen, and Jin-Hyo Boo

    E-Print Network [OSTI]

    Boo, Jin-Hyo

    Surface Plasma Treatment of Polyimide Film for Cu Metallization Sang-Jin Cho, Jin-Woo Choi, In online January 20, 2011 Surface modification of polyimide films by oxygen/argon atmospheric pressure on the surface properties of polyimide (PI) films were investigated in terms of Fourier-transform infrared (FT

  13. Effects of Collision and Vibrational Energy on the Reaction of CH3CHO+() with C2D4 Ho-Tae Kim, Jianbo Liu, and Scott L. Anderson*

    E-Print Network [OSTI]

    Anderson, Scott L.

    , we calculated the structures and energetics of 13 different complexes that potentially could serve vibrational state. REMPI through different vibrational levels of the B~ electronic state is used to produce CH dynamics with increasing energy. For the CH3CHO+- C2H4 system, there is an important direct mechanism even

  14. Expression of orphan G-protein coupled receptor GPR174 in CHO cells induced morphological changes and proliferation delay via increasing intracellular cAMP

    SciTech Connect (OSTI)

    Sugita, Kazuya; Yamamura, Chiaki; Tabata, Ken-ichi [Laboratory of Pharmacoinformatics, Graduate School of Ritsumeikan University, Kusatsu, Shiga 525-8577 (Japan)] [Laboratory of Pharmacoinformatics, Graduate School of Ritsumeikan University, Kusatsu, Shiga 525-8577 (Japan); Fujita, Norihisa, E-mail: nori@ph.ritsumei.ac.jp [Laboratory of Pharmacoinformatics, Graduate School of Ritsumeikan University, Kusatsu, Shiga 525-8577 (Japan) [Laboratory of Pharmacoinformatics, Graduate School of Ritsumeikan University, Kusatsu, Shiga 525-8577 (Japan); School of Pharmacy, Ristumeikan University, Kusatsu, Shiga 525-8577 (Japan)

    2013-01-04

    Highlights: Black-Right-Pointing-Pointer Expression of GPR174 in CHO cells induces morphological changes and proliferation delay. Black-Right-Pointing-Pointer These are due to increase in intracellular cAMP concentration. Black-Right-Pointing-Pointer Lysophosphatidylserine was identified to stimulate GPR174 leading to activate ACase. Black-Right-Pointing-Pointer The potencies of fatty acid moiety on LysoPS were oleoyl Greater-Than-Or-Slanted-Equal-To stearoyl > palmitoyl. Black-Right-Pointing-Pointer We propose that GPR174 is a lysophosphatidylserine receptor. -- Abstract: We established cell lines that stably express orphan GPCR GPR174 using CHO cells, and studied physiological and pharmacological features of the receptor. GPR174-expressing cells showed cell-cell adhesion with localization of actin filaments to cell membrane, and revealed significant delay of cell proliferation. Since the morphological changes of GPR174-cells were very similar to mock CHO cells treated with cholera toxin, we measured the concentration of intracellular cAMP. The results showed the concentration was significantly elevated in GPR174-cells. By measuring intracellular cAMP concentration in GPR174-cells, we screened lipids and nucleotides to identify ligands for GPR174. We found that lysophosphatidylserine (LysoPS) stimulated increase in intracellular cAMP in a dose-dependent manner. Moreover, phosphorylation of Erk was elevated by LysoPS in GPR174 cells. These LysoPS responses were inhibited by NF449, an inhibitor of G{alpha}{sub s} protein. These results suggested that GPR174 was a putative LysoPS receptor conjugating with G{alpha}{sub s}, and its expression induced morphological changes in CHO cells by constitutively activating adenylyl cycles accompanied with cell conjunctions and delay of proliferation.

  15. Photolysis of CH{sub 3}CHO at 248 nm: Evidence of triple fragmentation from primary quantum yield of CH{sub 3} and HCO radicals and H atoms

    SciTech Connect (OSTI)

    Morajkar, Pranay; Schoemaecker, Coralie; Fittschen, Christa; Bossolasco, Adriana

    2014-06-07

    Radical quantum yields have been measured following the 248 nm photolysis of acetaldehyde, CH{sub 3}CHO. HCO radical and H atom yields have been quantified by time resolved continuous wave Cavity Ring Down Spectroscopy in the near infrared following their conversion to HO{sub 2} radicals by reaction with O{sub 2}. The CH{sub 3} radical yield has been determined using the same technique following their conversion into CH{sub 3}O{sub 2}. Absolute yields have been deduced for HCO radicals and H atoms through fitting of time resolved HO{sub 2} profiles, obtained under various O{sub 2} concentrations, to a complex model, while the CH{sub 3} yield has been determined relative to the CH{sub 3} yield from 248 nm photolysis of CH{sub 3}I. Time resolved HO{sub 2} profiles under very low O{sub 2} concentrations suggest that another unknown HO{sub 2} forming reaction path exists in this reaction system besides the conversion of HCO radicals and H atoms by reaction with O{sub 2}. HO{sub 2} profiles can be well reproduced under a large range of experimental conditions with the following quantum yields: CH{sub 3}CHO?+?h?{sub 248nm} ? CH{sub 3}CHO{sup *}, CH{sub 3}CHO{sup *} ? CH{sub 3}?+?HCO??{sub 1a} = 0.125??0.03, CH{sub 3}CHO{sup *} ? CH{sub 3}?+?H?+?CO??{sub 1e} = 0.205??0.04, CH{sub 3}CHO{sup *}?{sup o{sub 2}}CH{sub 3}CO?+?HO{sub 2}??{sub 1f} = 0.07??0.01. The CH{sub 3}O{sub 2} quantum yield has been determined in separate experiments as ?{sub CH{sub 3}} = 0.33 0.03 and is in excellent agreement with the CH{sub 3} yields derived from the HO{sub 2} measurements considering that the triple fragmentation (R1e) is an important reaction path in the 248 nm photolysis of CH{sub 3}CHO. From arithmetic considerations taking into account the HO{sub 2} and CH{sub 3} measurements we deduce a remaining quantum yield for the molecular pathway: CH{sub 3}CHO{sup *} ? CH{sub 4}?+?CO??{sub 1b} = 0.6. All experiments can be consistently explained with absence of the formerly considered pathway: CH{sub 3}CHO{sup *} ? CH{sub 3}CO?+?H??{sub 1c} = 0.

  16. Characterization of four CHO mutants

    E-Print Network [OSTI]

    Brancheau, Michael Raymond

    1987-01-01

    moiety from 5-phosphoribosyl-1-pyrophos- phate (PRPP) to the 9 position of hypoxanthine or guanine to yield pyrophosphate plus lMP or GMP, respectively. Cells other than mature erythrocytes or lerminally differentiated friend erythroleukemia cells...

  17. The Ubiquitous DBMS Kyu-Young Whang1

    E-Print Network [OSTI]

    Song, Il-Yeol

    for ubiquitous devices such as flash memory [GT05] and MEMS (Micro-Electro-Mechanical Systems)- based storage in PCs and servers. Another type of storage media for ubiquitous devices is MEMS-based storage devices. A MEMS-based storage device is a secondary storage device and also has many advantages over the disk

  18. Introduction to k'yu ts'udalaas aa

    E-Print Network [OSTI]

    'udalaas aa Wood: chan is ii Shell Gill Siphon & Pallets WoodCaecum Margo Haygood adapted from Ruth TurnerValve Gill Siphon Anus #12;Where do shipworms live? Shipworms have been found in every ocean of the world, but also feed on plankton that they suck in through their siphons. 4 #12;Shipworm Anatomy Siphons extend

  19. CHO Invest EU1 | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION J APPENDIX E LISTStar Energy LLC JumpBiossenceBrunswick, Maine:IAEAT JumpCEECHO Invest EU1 Jump to:

  20. Enhanced Charge-Transfer Kinetics by Anion Surface Modi cation of Kyu-Sung Park,,

    E-Print Network [OSTI]

    Henkelman, Graeme

    . The intermittency of wind and solar energy makes mandatory large-scale energy storage as a complement of the electrical energy generated from wind and radiant solar power. Moreover, rechargeable batteries that power on global warming and air pollution, alternative energy sources at an a ordable price are urgently needed

  1. Bus-Aware Microarchitectural Floorplanning Dae Hyun Kim Sung Kyu Lim

    E-Print Network [OSTI]

    Lim, Sung Kyu

    and long, thereby consuming significant area, delay, and power. In our architecture, we have 51 buses on other important floorplanning objectives including area, performance, power, and thermal. We developed on area, performance, and power objectives under thermal constraint. I. INTRODUCTION Microarchitectural

  2. Downloading Hidden Web Content Alexandros Ntoulas Petros Zerfos Junghoo Cho

    E-Print Network [OSTI]

    Cho, Junghoo "John"

    in order to access the pages from certain Web sites. These pages are often referred to as the Hidden Web or the Deep Web. Since there are no static links to the Hidden Web pages, search engines cannot discover autonomously discover and download pages from the Hidden Web. Since the only "entry point" to a Hidden Web site

  3. University , DE{AC020{76{CHO{3073.

    E-Print Network [OSTI]

    Zakharov, Leonid E.

    PLASMA PHYSICS LABORATORY PPPL 3 #12; OUTLINE 1. Magnetic propulsion of liquid lithium. 2. Lithium Walls, Princeton NJ PRINCETON PLASMA PHYSICS LABORATORY PPPL 4 #12; 1 Magnetic propulsion of liquid lithium Goto PHYSICS LABORATORY PPPL 5 #12; 1 Magnetic propulsion of liquid lithium (cont.) There 3 magnetic Reynolds

  4. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    Mouad Menicon Co., Ltd. Immeuble Espace Cordeliers, 2, rue President Carnot, 69002 Lyon (France) (1) Lee, Taek Soon (1) Leong, Susanna (1) Leong, Susanna Su Jan School of...

  5. WEATHER, p. 2 Volume 131, Number 60 Wednesday, January 11, 2012

    E-Print Network [OSTI]

    Following the Republican rallies around New Hampshire opinion, p. 4 SpORT TAEkWONdO lEAdS d1 MIT is 120

  6. WEATHER, p. 2 Volume 131, Number 53 Friday, November 18, 2011

    E-Print Network [OSTI]

    rather low expectations ARTS, p. 8 TAEkWONdO dOmINATION Taekwondo owns the competition at MIT tourney

  7. Vacuum-ultraviolet ionization spectroscopy of the jet-cooled RNA-base Kyo-Won Choi, Joo-Hee Lee and Sang Kyu Kim*

    E-Print Network [OSTI]

    Kim, Sang Kyu

    Vacuum-ultraviolet ionization spectroscopy of the jet-cooled RNA-base uracil Kyo-Won Choi, Joo accurately and precisely determined for the first time using a vacuum-ultraviolet mass-analyzed threshold be used for the clarification of the latter in this report. Here, we employ a vacuum-ultraviolet mass

  8. Debonding and fracture of ceramic islands on polymer substrates Jeong-Yun Sun, Nanshu Lu, Juil Yoon, Kyu-Hwan Oh, Zhigang Suo et al.

    E-Print Network [OSTI]

    Suo, Zhigang

    is smaller than the interfacial toughness, the critical substrate strains for island fracture and debondingDebonding and fracture of ceramic islands on polymer substrates Jeong-Yun Sun, Nanshu Lu, Juil Yoon, 244706 (2011) Temperature-induced anomalous brittle-to-ductile transition of bulk metallic glasses Appl

  9. Influence of catechins on bystander responses in CHO cells induced by alpha-particle irradiation

    E-Print Network [OSTI]

    Yu, Peter K.N.

    radicals (Chaudhry, 2006). Catechins, a polyphenolic compound of green tea, are well known as scavengers). ()-epigallocatechin gallate (EGCG), which is a major constituent of green tea catechins, is the most active

  10. Privacy-Aware Communication for Smartphones Using Vibration Inhwan Hwang, Jungchan Cho, and Songhwai Oh

    E-Print Network [OSTI]

    methods, such as near field communication (NFC), radio-frequency identification (RFID), Wi-Fi, Zigbee] and suffers from the same shortcomings of NFC. While Wi-Fi [1], Bluetooth [4], and Zigbee [2] are widely

  11. About making a CHO production cell line research-friendly by genetic engineering

    E-Print Network [OSTI]

    2011-11-22

    (Icosagen AS, Tartu, Estonia) expressing the full length EBNA1 gene, and the HEK293-6E cell line (from the group of Y. Durocher, NRC, Canada) expressing a truncated EBNA1 gene served as positive controls. A number of commercially available anti-EBNA1... , Cambridge, United Kingdom. 3Cardiff University, Cardiff, United Kingdom. Published: 22 November 2011 References 1. Gaudry JP, Arod C, Sauvage C, Busso S, Dupraz P, Pankiewicz R, Antonsson B: Purification of the extracellular domain of the membrane protein...

  12. A Micropower Self-Clocked Camera-on-a-Chip Kwang-Bo Cho 1

    E-Print Network [OSTI]

    Fossum, Eric R.

    to be run from a watch battery. It is believed that this chip is the world's lowest power image sensor and the first image sensor designed for a watch battery operation. The camera-on-a-chip operates as a self of the art CMOS image sensors. The chip is designed for 1.2 - 1.7 V operation, supposedly from one battery

  13. Quadratic Regularization Design for 3D Axial CT Jang Hwan Cho and Jeffrey A. Fessler

    E-Print Network [OSTI]

    Fessler, Jeffrey A.

    conventional filtered back-projection (FBP) re- construction [1]. Regularized image reconstruction methods, such as penalized weighted least squares (PWLS) method or a penalized-likelihood (PL) method, provide noise control Impulse Response Consider a penalized weighted least squares (PWLS) objec- tive function of the form (x

  14. Modelling a CNTFET with Undeposited CNT Defects Geunho Cho, Fabrizio Lombardi, Yong-Bin Kim

    E-Print Network [OSTI]

    Ayers, Joseph

    and manufacturing a CNTFET, additional features such as pitch, number and position of the CNTs must be considered. INDEX TERMS: Defect model, CNT, CNTFET, manufacturing, emerging technologies 1. Introduction The Carbon manufacturing processes. In CNTFETs, ballistic or near-ballistic transport phenomena have been observed under

  15. Finite-size scaling theory for explosive percolation transitions Y. S. Cho,1

    E-Print Network [OSTI]

    Kim, Doochul

    and Rnyi model under the Achlioptas process. A scaling function is derived based on the observed fact of a giant cluster, called the Achlioptas process AP 1 , to the rule in the classic ER network model 9. Thus, the order parameter increases sud- denly. In analogy to the eruption of a volcano or a seismic

  16. I HC HAWAI`I TI MNOA THNG TIN CHO SINH VIN QUC T

    E-Print Network [OSTI]

    bang Hawai`i, Hoa K NM THNH LP: 1907 KIM NH CHT LNG: Hip Hi cc trng Ph thng v i hc Min Ty Hoa K DIN TCH: 1,3 km2 S LNG SINH VIN NHP HC: 20.006 S LNG SINH VIN QUC T: 2.351 QUY M LP HC: 21 sinh vin T L SINH VIN/GING VIN: 14/1 S LNG GING VIN TRNH TIN S: 85% CHNG TRNH O TO H C NHN*: 112

  17. Crawler-Friendly Web Servers Onn Brandman, Junghoo Cho, Hector Garcia-Molina, Narayanan Shivakumar

    E-Print Network [OSTI]

    Cho, Junghoo "John"

    that automatically downloads pages from the Web. A typical crawler starts with a seed set of pages (e.g., yahoo-to-date, for example, if the pages are used by a web search engine like AltaVista or Google. Thus, the crawler splits. The need to revisit pages generates even more demands on the crawler. To illustrate, the Web is currently

  18. CHO ET AL. VOL. 5 ' NO. 5 ' 36073613 ' 2011 www.acsnano.org

    E-Print Network [OSTI]

    Chen, Yong P.

    em- ployed as one of the experimental control knobs for a number of condensed matter systems on Cu foil at the nanoscale and atomic-scale caused by heat-treatment. We find that prolonged low oxidation. High-temperature an- nealing of the sample (at 700800 C) results in full recovery

  19. Pixel-Oriented Treemap for Display Ecologies Haeyong Chung, Yong Ju Cho, Jessica Self, Chris North

    E-Print Network [OSTI]

    of hurricane. A hurricane caused a blackout at the eastern coast. Several computers of region 25 go offline

  20. Yanglai Cho, at right, manning the ceremonial "shovel"

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorkingLos Alamos verifies largest single| National1958,1CaseYakama

  1. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    or suggestions for a way to improve these results? Numerical Verification of Bounce Harmonic Resonances in Neoclassical Toroidal Viscosity for Tokamaks Kimin Kim, Jong-Kyu Park...

  2. Numerical Verification of Bounce Harmonic Resonances in Neoclassical

    Office of Scientific and Technical Information (OSTI)

    for Tokamaks Kimin Kim, Jong-Kyu Park and Allen H. Boozer 70 PLASMA PHYSICS AND FUSION TECHNOLOGY Tokamaks, Numerical Verification Tokamaks, Numerical Verification This...

  3. TITLE AUTHORS SUBJECT SUBJECT RELATED DESCRIPTION PUBLISHER AVAILABILI...

    Office of Scientific and Technical Information (OSTI)

    Viscosity for Tokamaks Kimin Kim Jong Kyu Park and Allen H Boozer PLASMA PHYSICS AND FUSION TECHNOLOGY Tokamaks Numerical Verification Tokamaks Numerical Verification This Letter...

  4. A Long-Life, High-Rate Lithium/Sulfur Cell: A Multifaceted Approach...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Long-Life, High-Rate LithiumSulfur Cell: A Multifaceted Approach to Enhancing Cell Performance Min-Kyu Song, , Yuegang Zhang,* ,, and Elton J. Cairns* ,, The...

  5. Cho-k-NN: A Method for Combining Interacting Pieces of Evidence in Case-Based Learning

    E-Print Network [OSTI]

    Hllermeier, Eyke

    .g. a pattern along with its classification in pattern recognition or a problem along with a solution in case retrieved from a case library must not be considered as independent information sources, as implicitly done of classification and regression [Riesbeck and Schank, 1989; Kolodner, 1993]. As the term suggests, in CBL special

  6. Two-Character Motion Analysis and Synthesis Taesoo Kwon, Young-Sang Cho, Sang Il Park, and Sung Yong Shin

    E-Print Network [OSTI]

    -up martial arts such as Kickboxing, Karate, and Taekwondo performed by a pair of humanlike characters while and wrestling, martial arts such as Judo and Taekwondo, coupled dances such as tango and waltz, and so on, daily, Karate, and Taekwondo have attracted our attention because of its repertories of diverse and dynamic

  7. Cryptanalysis of Cho et al.'s Protocol, A Hash-Based Mutual Authentication Protocol for RFID Systems

    E-Print Network [OSTI]

    International Association for Cryptologic Research (IACR)

    been used in libraries, e-passports, manufacturing, inventory control, supply chain management, e Naderi1 1 Electrical Engineering Department, Iran University of Science and Technology, Tehran, Iran, {M Safkhani,M Nderi}@iust.ac.ir 2 Information Security and Privacy Lab, Delft University of Technology, Delft

  8. Cryptanalysis of Cho et al.'s Protocol, A HashBased Mutual Authentication Protocol for RFID Systems

    E-Print Network [OSTI]

    International Association for Cryptologic Research (IACR)

    chain management, e health and so on. The tag, the reader and the backend data base are three basic radio frequency signals by the reader. The backend data base mainly aids the reader by an extra storage application is data security which may waives all its benefits. For example, an RFID system may lead

  9. An Underwater Communication and Sensing Testbed in Marina del Rey Andrew Goodney, Young H. Cho, John Heidemann, John Wroclawski

    E-Print Network [OSTI]

    Heidemann, John

    underwater events such as oil spills, volcanic activity, and the like, more people are seeking innovative research progress. TESTBED DESIGN To deploy our testbed in the underwater environment, we have rented five

  10. NuEditor A Tool Suite for Specification and Verification of NuSCR Jaemyung Cho, Junbeom Yoo, Sungdeok Cha

    E-Print Network [OSTI]

    proposed to ensure safety. In nuclear power plant control systems, software safety became a critical issue system for nuclear power plant. SCR almost exclusively depended on fine-grained tabular notationsEditor to specify a trip logic of RPS(Reactor Protection System) BP(Bistable Processor) and verify its correctness

  11. High-Performance ZrO2-Coated LiNiO2 Cathode Material Jaephil Cho,a,

    E-Print Network [OSTI]

    Park, Byungwoo

    O2 has a high-fracture toughness of 8-12 MPa m.16 Experimental LiNiO2 powders were prepared from lattice structure. Since metal oxides with low ductility initiate mechanically induced micro- cracks

  12. Application of Interactive Genetic Algorithm to Fashion Design Hee-Su Kim and Sung-Bae Cho

    E-Print Network [OSTI]

    Cho, Sung-Bae

    since the Industrial Revolution is on the market economy. Think about clothes market. Before the Industrial Revolution, consumers had to make their own clothes or buy one from very small producers. Naturally they have few choices on it. However the Industrial Revolution enables mass-production, and now

  13. Fail Safe Design for Large Capacity Lithium-ion Batteries

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Fail Safe Design for Large Capacity Lithium-ion Batteries NREL Commercialization & Tech Transfer Webinar March 27, 2011 Gi-Heon Kim gi-heon.kim@nrel.gov John Ireland, Kyu-Jin Lee,...

  14. Power-Factor and Torque Calculation with Consideration of Cross Saturation of the Interior Permanent Magnet Synchronous Motor with

    E-Print Network [OSTI]

    Tolbert, Leon M.

    OF IPMSM Below is the well-known electromagnetic torque equation for all synchronous machines: dqqd iip Permanent Magnet Synchronous Motor with Brushless Field Excitation Seong Taek Lee1,2 , Timothy A. Burress1 permanent magnet synchronous motor (IPMSM). The conventional two-axis IPMSM model is modified to include

  15. IEEE 802.11 PSM happy1024@cs.yonsei.ac.kr, kimthun@cs.yonsei.ac.kr, yang@cs.yonsei.ac.kr

    E-Print Network [OSTI]

    Yang, Sung-Bong

    2 P2P IEEE 802.11 PSM O, , happy1024@cs.yonsei.ac.kr, kimthun@cs.yonsei.ac.kr, yang@cs.yonsei.ac.kr An Effective Power Saving Mechanism for IEEE 802.11 PSM In Double-layered Mobile P2P Systems JuHee Lee, Taek IEEE 802.11 (PSM) . PSM Beacon Interval Sleep . , Sleep

  16. Sonoluminescence from an isolated bubble on a solid surface K. R. Weninger, H. Cho, R. A. Hiller, S. J. Putterman, and G. A. Williams

    E-Print Network [OSTI]

    Williams, Gary A.

    to its freezing point of about 160 K 2,3 . These experiments are a preliminary step toward obtaining SL in cryogenic systems such as would be realized for helium bubbles trapped in liquid argon. A variable

  17. 11/11/2002 1AVS 49th Int'l Symp. MS-MoA7 (Oct. 29, 2002) -Cho Dynamic Simulation and Optimization

    E-Print Network [OSTI]

    Rubloff, Gary W.

    and may improve manufacturing productivity ("dual-use" ) Stimulate innovation through efforts to co & control systems Product mix, market dynamics Product mix, market dynamics WIP fluctuations WIP requirements of the industry ESH impact metrics exist within larger context of product performance

  18. RIKEN Center for Sustainable Resource Science 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045 Japan

    E-Print Network [OSTI]

    Fukai, Tomoki

    Genomics Research Team Enzyme Research Team Bioplastic Research Team Cell Factory Research Team Biomass

  19. Electronic structure of amorphous InGaO3(ZnO)0.5 thin films Deok-Yong Cho a

    E-Print Network [OSTI]

    Oh, Se-Jung

    in the field of active display devices, for example for organic-light-emitting-diode (OLED). In an effort of this a-IGZO film in a fabricated TFT was high enough (N10 cm2 /Vs) to be used in OLED displays [7

  20. Importance of plasma response to non-axisymmetric perturbations in tokamaks

    E-Print Network [OSTI]

    Princeton Plasma Physics Laboratory

    Importance of plasma response to non-axisymmetric perturbations in tokamaks Jong-kyu Park,1 Tokamaks are sensitive to deviations from axisymmetry as small as Bx/B 10-4. These non for understanding the sensitivity of tokamak plasmas to perturbations. IPEC calculations indicate the ideal plasma

  1. Energy Minimization of a Pipelined Processor using a Low Voltage Pipelined Cache

    E-Print Network [OSTI]

    Mooney, Vincent

    condition in the embedded systems area. Especially for mobile de- vices, power and energy usage canEnergy Minimization of a Pipelined Processor using a Low Voltage Pipelined Cache Jun Cheol Park, Vincent J. Mooney III, Krishna Palem and Kyu-won Choi School of Electrical and Computer Engineering

  2. 504 Min et al. Human NDP kinase A Acta Cryst. (2000). D56, 504505 crystallization papers

    E-Print Network [OSTI]

    Suh, Se Won

    2000-01-01

    -ray crystallographic analysis of human nucleoside diphosphate kinase A Kyeongsik Min,a Sun Young Kim,b Hyun Kyu. Correspondence e-mail: sewonsuh@snu.ac.kr # 2000 International Union of Crystallography Printed in Denmark all, 1973). The reaction has a ping-pong mechanism via a high-energy phosphohistidine intermediate

  3. Design, fabrication and analysis of a body-caudal fin propulsion system for a microrobotic fish

    E-Print Network [OSTI]

    Wood, Robert

    Design, fabrication and analysis of a body-caudal fin propulsion system for a microrobotic fish Kyu and fabrica- tion of a centimeter-scale propulsion system for a robotic fish. The key to the design are customized to provide the necessary work output for the microrobotic fish. The flexure joints, electrical

  4. One-Photon Mass-Analyzed Threshold Ionization Spectroscopy of Bis(6-benzene)chromium and Its Benzene and Ar Clusters

    E-Print Network [OSTI]

    Kim, Sang Kyu

    One-Photon Mass-Analyzed Threshold Ionization Spectroscopy of Bis(6-benzene)chromium and Its Benzene and Ar Clusters Kyo-Won Choi and Sang Kyu Kim* Department of Chemistry and School of Molecular-analyzed threshold ionization (MATI) spectroscopy of bis(6-benzene)chromium is reported. The adiabatic ionization

  5. Graphene coating makes carbon nanotube aerogels superelastic and resistant to fatigue

    E-Print Network [OSTI]

    McGaughey, Alan

    Graphene coating makes carbon nanotube aerogels superelastic and resistant to fatigue Kyu Hun Kim one and five layers of graphene nanoplates. The graphene-coated aerogel exhibits no change , but collapse under stress15 . We fabricated graphene-coated single-walled carbon nanotube aerogels by coating

  6. Copyright WILEY-VCH Verlag GmbH & Co. KGaA, 69469 Weinheim, Germany, 2012. Supporting Information

    E-Print Network [OSTI]

    McGaughey, Alan

    Accommodation in Single-Walled Carbon Nanotube Aerogels Scott N. Schiffres, Kyu Hun Kim, Lin Hu, Alan J. H. Mc diffusion, energy transport, and thermal accommodation in single-walled carbon nanotube aerogels Scott N. (b) This specific pore volume versus pore diameter plot shows that the aerogel contains predominantly

  7. A New DBMS Architecture for DB-IR Integration

    E-Print Network [OSTI]

    Whang, Kyu-Young

    A New DBMS Architecture for DB-IR Integration Kyu-Young Whang Computer Science Department. Nowadays, as there is an increasing need to integrate the DBMS (for structured data) with Information is required. In this talk, we present a new DBMS architecture applica- ble to DB-IR integration, which we call

  8. Effect of aspect ratios of in situ formed TiB whiskers on the mechanical properties of TiBw/Ti6Al4V composites

    E-Print Network [OSTI]

    Hong, Soon Hyung

    online 27 December 2011 Ti alloy matrix composites reinforced with nanosized TiB whiskers (TiBw/Ti6Al4V composites (TMCs) reinforced using disparate ceramics as reinforcing agents have been of great interest4V composites Min Young Koo,a Jae Sung Park,a Min Kyu Park,b Kyung Tae Kimc and Soon Hyung Honga

  9. Recent Journal Articles on Current Research Professor Martha Mecartney

    E-Print Network [OSTI]

    Mease, Kenneth D.

    , zirconia composites Author(s): Dillon RP (Dillon, R. Peter)1 , Kim DK (Kim, Dong-Kyu)2 , Trujillo JE of zircon during high temperature deformation of zirconia-silica composites with alumina additions Author of a fine grain three-phase alumina-zirconia-mullite ceramic composite Author(s): Chen TD, Mecartney ML

  10. Light Sets Tiny Objects Aquiver --Cho 2005 (712): 2 --sciencenow http://sciencenow.sciencemag.org/cgi/content/full/2005/712/2 1 of 2 7/14/2005 11:55 AM

    E-Print Network [OSTI]

    ://sciencenow.sciencemag.org/cgi/content/full/2005/712/2 1 of 2 7/14/2005 11:55 AM Hum along. Light pressure sets a tiny glass disk vibrating Tiny Objects Aquiver Much as a kid might make a soda bottle shake by blowing across its top and filling it with sound waves, physicists have set a tiny disk of glass vibrating by "whistling" light through it

  11. Nov. 5, 2003 1Soon Cho_AVS 50th International Symposium (Baltimore) RealReal--Time InTime In--Situ Chemical Sensing inSitu Chemical Sensing in

    E-Print Network [OSTI]

    Rubloff, Gary W.

    detection and classification Semi-quantitative sensing for process understanding In-situ chemical) Multi-use: compatible with fault detection and process learning Apply to GaN MOCVD for advanced Composer acoustic sensor GaN MOCVD PROCESS CHAMBER EMF MOCVD System Inficon Transpector mass spectrometer

  12. Rgulirement, Gosciences-Infos se fait l'cho du rayonnement international de GM, mme si son format est trop rduit pour rendre compte de l'tendue relle de ces activits. Le

    E-Print Network [OSTI]

    Demouchy, Sylvie

    - dito Rgulirement, Gosciences-Infos se fait l'cho du rayonnement international de GM, mme si-chercheurs du laboratoire dans pas moins de cinq sessions du congrs de l'AGU San Francisco. L'attrait de GM CNRS-Organismes (Algrie, Australie, Egypte, Irlande, Maroc, Tawan...). GM est particulirement

  13. Search for: All records | DOE PAGES

    Office of Scientific and Technical Information (OSTI)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefieldSulfateSciTechtail. (Conference) |Janka, Oliver" Name NameKennedy,SwitchSwitch toDale,daLee, Taek

  14. African American Fathers Perceptions of Childhood Overweight: An Exploratory Study

    E-Print Network [OSTI]

    Byrd, Vanessa

    2012-02-14

    Childhood overweight/obesity (CHO) is a serious health concern for children and adolescents. Despite increased efforts to prevent CHO, prevalence rates have actually increased. Evidence suggests that parents are critical ...

  15. Biophysical characterization of p53 regulatory domain and MDM2

    E-Print Network [OSTI]

    Cheung, Nikki Hoi Ling

    2010-01-01

    site as a self-assembled tetramer. Structure, 18, CHO, Y. ,site as a self- assembled tetramer. Structure, 18, CHO, Y. ,product form anti-parallel tetramers in solution. Proc Natl

  16. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    H:C vs O:C van Krevelen diagram, CHO index allowed for direct visualization of the distribution of heteroatoms such as N in the identified SOM compounds. We demonstrate that CHO...

  17. Optical and thermodynamic properties of the high-temperature superconductor HgBa2CuO4+ E. van Heumen,1 R. Lortz,1 A. B. Kuzmenko,1 F. Carbone,1 D. van der Marel,1 X. Zhao,2 G. Yu,2 Y. Cho,2

    E-Print Network [OSTI]

    Johnson, Peter D.

    Laboratory, Stanford University, Stanford, California 94305, USA 3Condensed Matter Physics and Materials corresponds to a change in kinetic energy W 0.5 meV/Cu which is more than enough to explain the condensation is highly hygroscopic and does not cleave naturally along the ab plane. Therefore we polished the sample

  18. C-H...O interactions and stacking of water molecules between pyrimidine bases in 5-nitro-1-([beta]-D-ribosyluronic acid)-uracil monohydrate [1-(5-nitro-2,4-dioxopyrimidinyl)-[beta]-D-ribofuranoic acid monohydrate]: a neutron diffraction study at 80 K

    E-Print Network [OSTI]

    Takusagawa, Fusao; Koetzle, Thomas F.; Srikrishnan, T.; Parthasarathy, R.

    1979-06-01

    . & LEVY, H. A. (1962) ORFLS. Report ORNL-TM-305. Oak Ridge National Laboratory, Tennessee. CHIDAMBARAM, R. , SEQUEIRA, A . & SIKKA, S. K. (1964) J Chem. Phys. 41, 3 6 1 6 - 3 6 2 2 . DIMMLER, D . G. , GREENLAW, N. , KELLEY, M. A., POTTER, D . W.... Birmingham: Kynoch Press. I U P A C - I U B COMMISSION ON BIOCHEMICAL NOMEN- CLATURE (1970) . J. Mol. Biol. 52, 1 - 1 7 . JOHNSON, C . K . (1976) . ORTEP II . Report ORNL-5138. Oak Ridge National Laboratory, Tennessee. KOETZLE, T . F . , HAMILTON, W . C...

  19. Polysubstance and alcohol dependence: Unique abnormalities of magnetic resonance-derived brain metabolite levels

    E-Print Network [OSTI]

    Ab, C; Mon, A; Durazzo, TC; Pennington, DL; Schmidt, TP; Meyerhoff, DJ

    2013-01-01

    synthesis, cellular bioenergetics, glio- sis) and alteredCho), cellular bioenergetics (Creatine, Cr), astroglio-to abnor- mal cellular bioenergetics (lower Cr; Licata and

  20. Chemical reactivities of ambient air samples in three Southern California communities

    E-Print Network [OSTI]

    2015-01-01

    and A.K. Cho. 2012. The chemical biology of naphthoquinonesinvolvement of organic chemicals and oxidative stress. Curr.www.tandfonline.com/loi/uawm20 Chemical reactivities of

  1. [Vietnamese] Tiu Nghin cu

    E-Print Network [OSTI]

    Biederman, Irving

    . Nhn c mt bn sao c ch k v ngy thng ca t mu chp thun cho cuc nghin cu . 10. C hi ty chp thun

  2. Publications

    E-Print Network [OSTI]

    $author.value

    [1], David W. Catlin and Sanghyun Cho. Extension of CR structures on three dimensional compact pseudoconvex CR manifolds. Math. Ann., 334(2):253-280,

  3. Advanced Electrical Characterization of Semiconductor Nanowires

    E-Print Network [OSTI]

    Khanal, Devesh Raj

    2010-01-01

    MOSFETs . . . . . . . . . . . . . . . Electrical Propertiesof surface states on electrical characteristics of inn andCho, and H. -Y. Cha, Electrical properties of ingan grown

  4. Rational Material Architecture Design for Better Energy Storage

    E-Print Network [OSTI]

    Chen, Zheng

    2012-01-01

    decondensation, Energy and Environmental Science 2011, 4, [Y. Lee, J. Cho, Energy & Environmental Science 2009, 2, T.lithium storage. Energy & Environmental Science 2011, 4, (

  5. Protection of atherogenesis in thromboxane A2 receptor-deficient...

    Office of Scientific and Technical Information (OSTI)

    ; Yokode, Masayuki 1 + Show Author Affiliations Department of Clinical Innovative Medicine, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku,...

  6. SUPPLEMENTARY DATA GBshape: a genome browser database for DNA shape

    E-Print Network [OSTI]

    Rohs, Remo

    hoffmanni Jul. 2008 (Broad/choHof1) Cat Felis catus Sep. 2011 (ICGSC Felis_catus 6.2/felCat5) Tree shrew

  7. Page 1 of 7 CHEMISTRY 3331, Spring 2005

    E-Print Network [OSTI]

    Walba, David

    - galactopyranose. Draw your structures carefully, and please leave out the H atoms. CHO OHH HHO HHO CH2OH OHH D

  8. EXTRAGALACTIC BACKGROUND LIGHT FROM HIERARCHICAL GALAXY FORMATION...

    Office of Scientific and Technical Information (OSTI)

    States) Max-Planck-Institut fuer Kernphysik, Saupfercheckweg 1, D-69117 Heidelberg (Germany) Research Center for Space and Cosmic Evolution, Ehime University, Bunkyo-cho,...

  9. Kriegstein, A., and Alvarez-Buylla, A. (2009). Annu. Rev. Neurosci. 32, 149184.

    E-Print Network [OSTI]

    Wahl, Geoffrey M.

    2009-01-01

    .E., Wang, J., Tewari, A.K., Eroshkin, A., Cho, Y.J., Witt, H., Korshunov, A., Read, T.A., Sun, J.L., et al

  10. Nonlinear quantum well photodetectors using frequency up conversion

    E-Print Network [OSTI]

    Chaganti, Venkata Ramalaxmi

    2009-05-15

    , E. Cubukcu, D. L. Sivco, and A. Y. Cho., Nature 433, 845 (2005). [19] A. Wojcik, F. Xie, Y. Cho, V. Chaganti, A. Belyanin, and J. Kono., J. Modern. Opt ?in press? (2008). [20] S. Pellegrini, R. E. Warburton, and J. J. Lionel, IEEE J. Quantum...

  11. 14 Chng 14: D an e xuat giam anh bat nham tang noi do s dung cau vang

    E-Print Network [OSTI]

    sn ti VNH MEXICO), cng nh loi mc tiu c kch thc nh hn. D n s n b cho ng dn t nguyn trnh s dng ng vy xanh. D n cng s cung cp cho ng dn tham gia hai loi thit b nh bt thay th nh bt lin tc c

  12. Analysis of C H...O hydrogen bonds

    E-Print Network [OSTI]

    Babu, M. Madan

    1 Analysis of C H...O hydrogen bonds in high resolution protein crystal structures from the PDB 1.4 Identification of C-H...O hydrogen bonds............................................. 1.4.1 The definition of a C-H...O hydrogen bond.................................... 1.4.2 Fixing the hydrogen and measuring the parameters

  13. Atmos. Chem. Phys., 10, 1014510160, 2010 www.atmos-chem-phys.net/10/10145/2010/

    E-Print Network [OSTI]

    Meskhidze, Nicholas

    of oxygenated VOCs: what can we learn from the ratio glyoxal to formaldehyde on a global scale? M. Vrekoussis1 of glyoxal (CHO.CHO) and formaldehyde (HCHO) were retrieved for the first time from measurements, production (Roberts et al., 2002). In order to assess the significance of VOCs in controlling at- mospheric

  14. Loi hnh trng: a ngnh, trng cng lp, i hc l trung tm nghin cu.

    E-Print Network [OSTI]

    Hickman, Mark

    100 hc bng dành cho sinh viên quc t và Chính ph New Zealand cng cho thêm nhiu hc bng khác na. · Các

  15. The integrin alpha 9 beta 1 contributes to granulopoiesis by enhancing granulocyte colony-stimulating factor receptor signaling

    E-Print Network [OSTI]

    Chen, Chun; Huang, Xiaozhu; Atakilit, Amha; Zhu, Quan-Sheng; Corey, Seth J; Sheppard, Dean

    2006-01-01

    phosphorylated in cells expressing wild type, full-length ?9b) CHO cells expressing G-CSF receptor and full-lengthcells were infected with a retrovirus expressing full-

  16. http://w3.pppl.gov/~ Development

    E-Print Network [OSTI]

    Zakharov, Leonid E.

    is supported by US DoE contract No. DE--AC020--76--CHO--3073. PRINCETON PLASMA PHYSICS LABORATORY PPPL #12 . . . . . . . . . . . . . . . . 7 1.2 Past and present history of Li

  17. Statistica Sinica 23 (2013), 901-927 doi:http://dx.doi.org/10.5705/ss.2011.058

    E-Print Network [OSTI]

    Qu, Annie

    2013-01-01

    FOR CORRELATED DATA WITH DIVERGING NUMBER OF PARAMETERS Hyunkeun Cho and Annie Qu University of Illinois on the quadratic inference function to incorporate correlation in- formation. These approaches are the best sub

  18. Biomimetic Synthesis of Noble Metal Nanoparticles and Their Applications as Electro-catalysts in Fuel Cells

    E-Print Network [OSTI]

    Li, Yujing

    2012-01-01

    Stamenkovic, V. ; Ross, P. N. Fuel Cells Min, M. K. ; Cho,Stamenkovic, V. ; Ross, P. N. Fuel Cell B643. Dillon, R. ;Hormes, J. ; Behm, R. J. Fuel Cells 2006 , 6 , 190. Wang, H.

  19. Manganese porphyrin multilayer films assembled on ITO electrodes via zirconium phosphonate chemistry: chemical and electrochemical

    E-Print Network [OSTI]

    chemistry: chemical and electrochemical catalytic oxidation activity So-Hye Cho, SonBinh T. Nguyen of 1.20 V. The electrochemically generated active intermediate exhibited oxidative catalytic activity; styrene epoxidation; supported catalysts; carbamazepine; electrochemical catalytic oxidation. 1

  20. Quantitative cue-signal-response analysis of EGF-induced cell migration

    E-Print Network [OSTI]

    Harms, Brian David, 1976-

    2004-01-01

    (cont.) curve is explained mechanistically by the results of the first study. In a final study, we investigated the phenomenological structure of CHO-EGFR cell paths using turn angle distribution and time series analyses. ...

  1. The evolution of farnesoid X, vitamin D, and pregnane X receptors: insights from the green-spotted pufferfish (Tetraodon nigriviridis) and other non-mammalian species

    E-Print Network [OSTI]

    2011-01-01

    5b-cho- lan-24-oic acid; LCA), a compound known to be toxictoxic second- ary bile acid LCA and its derivatives [7,50-and reduce the toxicity of LCA [52-56]. We pre- viously

  2. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    Peel-and-Stick: Mechanism Study for Efficient Fabrication of FlexibleTransparent Thin-film Electronics Lee, C. H. ; Kim, J. H. ; Zou, C. Y. ; Cho, I. S. ; Weisse, J. M. ; Nemeth,...

  3. Electrochemistry A Mesoporous/Crystalline Composite Material

    E-Print Network [OSTI]

    Park, Byungwoo

    as the Anode in Lithium-Ion Batteries** Eunjin Kim, Dongyeon Son, Tae-Gon Kim, Jaephil Cho,* Byungwoo Park for graphite,[1] many studies on Sn-based materials for use as anode materials have been performed.[2

  4. Synthesis and Morphological, Electrochemical Characterization of Sn92Co8 Nanoalloys for Anode Materials in Li Secondary

    E-Print Network [OSTI]

    Cho, Jaephil

    Materials in Li Secondary Batteries Hyunjung Kim and Jaephil Cho*,z Department of Applied Chemistry, Kumoh the capacity limits of graphite materials, Sn and Si anode materials have been investigated.1-3 However

  5. Active Hypothermic Growth: A Novel Means For Increasing Total Interferon-? Production by Chinese Hamster Ovary Cells

    E-Print Network [OSTI]

    Stephen R., Fox

    When grown under hypothermic conditions, Chinese Hamster Ovary (CHO) cells become growth arrested in the G?/G? phase of the cell cycle and also often exhibit increased recombinant protein production. In this study, we ...

  6. Dean's List, Fall 2013 Daniel Abarbanel

    E-Print Network [OSTI]

    Dellaire, Graham

    Chapman Yasmine Charlton Tse-An Chen Meghan Chen Tianmu Chen Jessica Chisholm Peter Cho Yun Hao Chou Jordan O'Hanlon Jonathon Orr Kathleen Orrell William Ounjian Jade Panzarasa Maggie-Jane Parker Paul Parks

  7. Cancer Research UK Clinical Trials Unit School of Cancer Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT

    E-Print Network [OSTI]

    Birmingham, University of

    of intrathecal Etoposide as a continuous infusion investigating duration and rate of infusion in patients/II dose schedule finding study of CH14.18/CHO continuous infusion combined with subcutaneous aldesleukin

  8. Seasonal measurements of acetone and methanol: Abundances and implications for atmospheric budgets

    E-Print Network [OSTI]

    Goldstein, Allen

    . The ratio was highest during fall and winter, probably a result of secondary acetone production from diffuse oxidized compounds formaldehyde (HCHO), and acetaldehyde (CH3CHO), whose atmospheric sources are dominated

  9. NANOCOMPOSITE ENABLED SENSITIZED SOLAR CELL

    E-Print Network [OSTI]

    Phuyal, Dibya

    2012-01-01

    55, 15. S.A. Haque, E. Palomares, B.M. Cho, A.N.M Green, N.2011. 36. J.N Clifford, E. Palomares, M. K. Nazeeruddin, M.

  10. Analysis of the levels of lysine-specific demethylase 1 (LSD1) mRNA in human ovarian tumors and the effects of chemical LSD1 inhibitors in ovarian cancer cell lines

    E-Print Network [OSTI]

    Konovalov, Sergiy; Garcia-Bassets, Ivan

    2013-01-01

    would like to thank the Ovarian Cancer Research Foundation (Cho KR, Shih I-M: Ovarian cancer. Annu Rev Pathol 2009, 4:of serous and endometrioid ovarian cancer linked to clinical

  11. Advanced method for high-throughput expression of mutated eukaryotic...

    Office of Scientific and Technical Information (OSTI)

    ; Murata, Takeshi 2 ; Department of Medical Chemistry, Kyoto University, Faculty of Medicine, Konoe-cho, Yoshida, Sakyo-Ku, Kyoto 606-8501 4 ; Abe, Keiko 1 ; Iwata, So 2 ;...

  12. Fluorescence-based optimization of human bitter taste receptor...

    Office of Scientific and Technical Information (OSTI)

    ; Murata, Takeshi 2 ; Department of Medical Chemistry, Kyoto University Faculty of Medicine, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606-8501 4 ; Abe, Keiko 1 ; Iwata, So,...

  13. Micro-bioreactor design for Chinese hamster ovary cells

    E-Print Network [OSTI]

    Goh, Shireen

    2013-01-01

    The research objective is to design a micro-bioreactor for the culture of Chinese Hamster Ovary (CHO) cells. There is an increasing demand for upstream development in high-throughput micro-bioreactors specifically for the ...

  14. Towards Energy Aware Scheduling for Precedence Constrained Parallel

    E-Print Network [OSTI]

    Towards Energy Aware Scheduling for Precedence Constrained Parallel Tasks: Jong Youl Cho Community Grids Lab, Indian University #12;Outlook Background;Energy model #12;Cluster model #12;Job model DAG model: T= (J, E) #12;Job

  15. Genome-wide Transcriptome Analysis of Laminar Tissue During the Early Stages of Experimentally Induced Equine Laminitis

    E-Print Network [OSTI]

    Wang, Jixin

    2012-02-14

    an equine 21,000 70-mer long oligoarray approach in CHO, HI and OF induced laminitis. Overall, we identified the differential expression of genes encoding S100 calcium binding proteins, extracellular matrix proteins, glycoproteins, transporters, olfactory...

  16. The UDUTDecomposition of Manipulator Inertia Matrix Subir Kumar Saha

    E-Print Network [OSTI]

    Saha, Subir Kumar

    The UDUTDecomposition of Manipulator Inertia Matrix Subir Kumar Saha R&D Center, Toshiba Corporation 4-1 Ukishima-cho, Kawasaki-ku, Kawasaki 210, Jalpan E-mail: sahaC3mel

  17. In vitro osteoclast formation and resorption of silicon-substituted hydroxyapatite ceramics

    E-Print Network [OSTI]

    Friederichs, Robert J.; Brooks, Roger A.; Ueda, Masato; Best, Serena M.

    2015-04-22

    Engineering, Faculty of Chemistry, Materials & Bioengineering, Kansai University, 3-3-35 Yamate-cho Suita Osaka 564-8680, Japan 2 ABSTRACT Materials that participate in bone remodelling at the implant / tissue interface represent a modern tissue engineering...

  18. Hc ph $13,160 Nh $8,920

    E-Print Network [OSTI]

    Gering, Jon C.

    Hc ph $13,160 Nh $8,920 Cc khon chi khc $3,532 Tng cng $25,612 XP HNG QUC GIA, CHI PH HP L nhc Chp nhn ng vin sau khi hon thnh kho hc Tng cng Anh ng Hc Bng Tt c ng vin u c cn nhc cho hc hc da trn thnh tch hc tp Chi Ph Chi ph c tnh cho nm hc 2014-2015 Kho Tng Cng Anh Ng / ESL

  19. i hc ng cp th gii i hc Binghamton, i hc Tiu bang New York, to dng c danh ting ca

    E-Print Network [OSTI]

    Zhang, Zhongfei "Mark"

    nht ti New York v ng th 18 trong c nc. Mt s l do gm kh nng duy tr s lng sinh vin, t l tt nghip cho cc sinh vin i hc c hng nn gio dc cht lng cao vi chi ph phi chng. i hc Binghamton mang n cho tip cng nh l lun nh tnh v nh lng. H cng c c hi tin hnh nghin cu, lm vic trn c s cng tc v

  20. Kh trng khn cp nc ung Trong nhng thi k ri ren, cc s y t a phng c th khuyn co ngi dn dng nc thn

    E-Print Network [OSTI]

    nc cho gia nh bn, bn vn c th tm c s lng gii hn dng bng cch ly nc ra t bnh nc nng, hay l tan nc ni . Thuc kh trng t hiu nghim nu nc c. Cn phi lc nc c qua nhng khn sch hoc yn cho lng xung, v khng b r st. C hai phng php kh trng thng dng v hiu qu nu lng nc t. Phng php th nht l un

  1. Current Status of the SANAEM RFQ Accelerator Beamline

    E-Print Network [OSTI]

    Turemen, G; Ogur, S; Yildiz, V; Mete, O; Oz, S; Ozbey, A; Yildiz, H; Yaman, F; Akgun, Y; Alacakir, A; Bolukdemir, S; Bozbey, A; Sahin, A; Unel, G; Erhan, S

    2015-01-01

    The design and production studies of the proton beamline of SPP, which aims to acquire know-how on proton accelerator technology thru development of man power and serves as particle accelerator technologies test bench, continue at TAEK-SANAEM as a multi-phase project. For the first phase, 20 keV protons will be accelerated to 1.3 MeV by a single piece RFQ. Currently, the beam current and stability tests are ongoing for the Inductively Coupled Plasma ion source. The measured magnetic field maps of the Low Energy Beam Transport solenoids are being used for matching various beam configurations of the ion source to the RFQ by computer simulations. The installation of the low energy diagnostics box was completed in Q1 of 2015. The production of the RFQ cavity was started with aluminum 7075-T6 which will be subsequently coated by Copper to reduce the RF (Ohmic) losses. On the RF side, the development of the hybrid power supply based on solid state and tetrode amplifiers continues. All RF transmission components hav...

  2. Mechanism of Methanol Synthesis on Cu through CO2 and CO Hydrogenation

    SciTech Connect (OSTI)

    Grabow, Lars C.; Mavrikakis, Manos

    2011-03-04

    We present a comprehensive mean-field microkinetic model for the methanol synthesis and water-gas-shift (WGS) reactions that includes novel reaction intermediates, such as formic acid (HCOOH) and hydroxymethoxy (CH?O?) and allows for the formation of formic acid (HCOOH), formaldehyde (CH?O), and methyl formate (HCOOCH?) as byproducts. All input model parameters were initially derived from periodic, self-consistent, GGA-PW91 density functional theory calculations on the Cu(111) surface and subsequently fitted to published experimentalmethanol synthesis rate data, which were collected under realistic conditions on a commercial Cu/ZnO/Al?O? catalyst. We find that the WGS reaction follows the carboxyl (COOH)-mediated path and that both CO and CO? hydrogenation pathways are active for methanol synthesis. Under typical industrial methanol synthesis conditions, CO? hydrogenation is responsible for ?2/3 of the methanol produced. The intermediates of the CO? pathway for methanol synthesis include HCOO*, HCOOH*, CH?O?*, CH?O*, and CH?O*. The formation of formate (HCOO*) from CO?* and H* on Cu(111) does not involve an intermediate carbonate (CO?*) species, and hydrogenation of HCOO* leads to HCOOH* instead of dioxymethylene (H?CO?*). The effect of CO is not only promotional; CO* is also hydrogenated in significant amounts to HCO*, CH?O *, CH?O*, and CH?OH*. We considered two possibilities for CO promotion: (a) removal of OH* via COOH* to form CO? and hydrogen (WGS), and (b) CO-assisted hydrogenation of various surface intermediates, with HCO* being the H-donor. Only the former mechanism contributes to methanol formation, but its effect is small compared with that of direct CO hydrogenation to methanol. Overall, methanol synthesis rates are limited by methoxy (CH?O*) formation at low CO?/(CO+CO?) ratios and by CH?O* hydrogenation in CO?-rich feeds. CH?O* hydrogenation is the common slow step for both the CO and the CO? methanol synthesis routes; the relative contribution of each route is determined by their respective slow steps HCO*+H*?CH?O*+* and HCOOH*+H*?CH?O?*+* as well as by feed composition and reaction conditions. An analysis of the fitted parameters for a commercial Cu/ZnO/Al?O? catalyst suggests that a more open Cu surface, for example, Cu(110), Cu(100), and Cu(211) partially covered by oxygen, may provide a better model for the active site of methanol synthesis, but our studies cannot exclude a synergistic effect with the ZnO support.

  3. Indexing Permafrost Soil Organic Matter Degradation Using High-Resolution Mass Spectrometry

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Mann, Benjamin F.; Chen, Hongmei; Herndon, Elizabeth M.; Chu, Rosalie K.; Tolic, Nikola; Portier, Evan F.; Roy Chowdhury, Taniya; Robinson, Errol W.; Callister, Stephen J.; Wullschleger, Stan D.; et al

    2015-06-12

    Microbial degradation of soil organic matter (SOM) is a key process for terrestrial carbon cycling, although the molecular details of these transformations remain unclear. This study reports the application of ultrahigh resolution mass spectrometry to profile the molecular composition of SOM and its degradation during a simulated warming experiment. A soil sample, collected near Barrow, Alaska, USA, was subjected to a 40-day incubation under anoxic conditions and analyzed before and after the incubation to determine changes of SOM composition. A CHO index based on molecular C, H, and O data was utilized to codify SOM components according to their observedmoredegradation potentials. Compounds with a CHO index score between 1 and 0 in a water-soluble fraction (WSF) demonstrated high degradation potential, with a highest shift of CHO index occurred in the N-containing group of compounds, while similar stoichiometries in a base-soluble fraction (BSF) did not. Additionally, compared with the classical H:C vs O:C van Krevelen diagram, CHO index allowed for direct visualization of the distribution of heteroatoms such as N in the identified SOM compounds. We demonstrate that CHO index is useful not only in characterizing arctic SOM at the molecular level but also enabling quantitative description of SOM degradation, thereby facilitating incorporation of the high resolution MS datasets to future mechanistic models of SOM degradation and prediction of greenhouse gas emissions.less

  4. United States Department of Commerce National Oceanic and Atmospheric Administration

    E-Print Network [OSTI]

    cung-cp nhng c lng cng-sc hot ng chnh xc cho vic nh bt tm. Tuy-nhin, hp-ng vi S Lin-Kt ng-v nhng c lng chnh xc t l cho c-hng-con b-cht ty thuc-vo ngnh hi-sn tm l iu ch-yu trong k-hnh v l mt cch tin-li v hiu qu nht xc nh chnh xc s lng v v tr nhng cng-sc hat-ng xy ra trong

  5. United States Department of Commerce National Oceanic and Atmospheric Administration

    E-Print Network [OSTI]

    -Thi LGL ang cung-cp nhng c lng cng-sc hot ng chnh xc cho vic nh-bt tm. Tuy-nhin, hp-ng vi S Lin-v nhng c lng chnh xc t l cho c-hng-con b-cht ty thuc-vo ngnh nh-bt tm l iu ch-yu trong k-Ngh-Nghip iu-hnh v l mt cch tin-li v hiu qu nht xc nh chnh xc s lng v v tr nhng cng-sc hat-ng xy ra

  6. Catalytic reforming methods

    SciTech Connect (OSTI)

    Tadd, Andrew R; Schwank, Johannes

    2013-05-14

    A catalytic reforming method is disclosed herein. The method includes sequentially supplying a plurality of feedstocks of variable compositions to a reformer. The method further includes adding a respective predetermined co-reactant to each of the plurality of feedstocks to obtain a substantially constant output from the reformer for the plurality of feedstocks. The respective predetermined co-reactant is based on a C/H/O atomic composition for a respective one of the plurality of feedstocks and a predetermined C/H/O atomic composition for the substantially constant output.

  7. Unsupervised Deep Learning: A Short Review Juha Karhunen1

    E-Print Network [OSTI]

    Karhunen, Juha

    Unsupervised Deep Learning: A Short Review Juha Karhunen1 , Tapani Raiko1 , and KyungHyun Cho2 1. Deep neural networks with several layers have during the last years become a highly successful and applications. A key idea in deep learning is to not only learn the nonlinear mapping between the inputs

  8. Subscriber: MIT | Sign In as Individual | FAQ | Access Rights | Join AAAS 12 September 2003

    E-Print Network [OSTI]

    condensate (BEC), in which ultracold atoms crowd into a single quantum state. Using laser light, researchers-Einstein condensates off solid surfaces. --ADRIAN CHO Related sites The Ketterle group home page The Grimm group home -- sciencenow The Levitron?home page How the Levitron?works Next Story ScienceNOW Home Copyright 2003

  9. Proceedingsof the 9th InternationalConference on NeuralInformation Processing(ICONIP`OZ), Vol. 3

    E-Print Network [OSTI]

    Cho, Sung-Bae

    SUPPORTVECTOR MACHINE FOR UNLABELEDDATA CLASSIFICATION JinHyuk Hong and Sung-Bue Cho hjinh amount of information has been produced as digital data format It is impossible to class classification has been grown. Machine leaming technologieshave applied in text classification. However

  10. Dual-band internal antenna ofPIFA type for mobile handsets and the effect of the handset case and battery

    E-Print Network [OSTI]

    Park, Seong-Ook

    Dual-band internal antenna ofPIFA type for mobile handsets and the effect of the handset case and battery Young-Jun Cho*, Soon-Ho Hwang, Osami Ishida, and Seong-Ook Park Information and Communications the influence of the handset case and battery. The proposed antenna operates at KPCS (1750-1870 MHz

  11. IEEE ANTENNAS AND WIRELESS PROPAGATION LETTERS, VOL. 4, 2005 429 A Dual-Band Internal Antenna With a Parasitic Patch

    E-Print Network [OSTI]

    Park, Seong-Ook

    With a Parasitic Patch for Mobile Handsets and the Consideration of the Handset Case and Battery Young Jun Cho the influences of the handset case and battery. A low-profile design is implemented on both the top and bottom and battery ( VSWR 2 ) can cover 140 MHz (17401880 MHz) in the Korean personal communica- tion service (KPCS

  12. Brainstem areas controlling the motor inhibition of animal hypnosis

    E-Print Network [OSTI]

    McBride, Russell Leavitt

    1968-01-01

    hattorX, with the electrode aud tho wire fran the- positivo yole of tho batterX . in salinoX x~ bubbles coro given off only at Cho electrode tip, tho insulatian wao incest {sures, et. ~. , 1'F), After stripping, the egposed ends, individual wires were...

  13. Protein Structure Modeling With MODELLER Narayanan Eswar$

    E-Print Network [OSTI]

    Sali, Andrej

    of MODELLER to construct a comparative model for a protein with unknown structure. Automation of similar se- quence and the template(s); (iii) building a model based on the alignment with the cho- sen user intervention and within minutes on a desktop computer. Apart from model building, MODELLER can

  14. Edge Preserving Region Growing for Aerial Color Image Segmentation

    E-Print Network [OSTI]

    Cho, Sung-Bae

    Statistical Institute, Kolkata 700108, India e-mail: subudhi.badri@gmail.com A. Ghosh e-mail: ash, Tiruchirappalli 620015, India e-mail: ishan.patwa@gmail.com S.-B. Cho Soft Computing Laboratory, Department@cs.yonsei.ac.kr Springer India 2015 L.C. Jain et al. (eds.), Intelligent Computing, Communication and Devices

  15. On Routing Schemes for Switch-Based In-Vehicle Shuhui Yang, Wei Li, and Wei Zhao

    E-Print Network [OSTI]

    Bystroff, Chris

    , network solutions we discover can be readily utilized in a wide range of practical automotive systems of functional components in different locations [Cho95] [KWMH96] [Kop99] [LH02a]. Before the era of automotive electronic systems, communication in the system was performed by mechanical or hydraulic means. A modern

  16. Mechanism of radiation-induced bystander effect: Role of the cyclooxygenase-2 signaling pathway

    E-Print Network [OSTI]

    Brenner, David Jonathan

    and carcinogenesis. At doses above 50 millisievert, the radiation- induced cancer risk can be estimated based, these irradiated cells. There is evidence that very low doses of -particles induced clastogenic responses by a particle (3, 5, 9). In CHO cells irradiated with low doses of particles where 1% of the nuclei were

  17. High-Level Information An Approach for Integrating Front-End and Back-End Compilers

    E-Print Network [OSTI]

    Li, Zhiyuan

    High-Level Information ­ An Approach for Integrating Front-End and Back-End Compilers Sangyeun Cho-end and back-end compilers by passing front-end information to the back-end compiler. Importing this information into an existing back- end leverages the state-of-the-art analysis and transforma- tion

  18. 2003 Peered Reviewed Archival Publications Chemical Engineering

    E-Print Network [OSTI]

    Mohaghegh, Shahab

    2003 Peered Reviewed Archival Publications Chemical Engineering Cho, E.H. and R. Chamarthy. 2003 for methane reforming with carbon dioxide over a mixed-metal carbide catalyst. I&EC Research 42: 2712-2721. Li-reduced, activated-carbon-supported, molybdenum-based catalysts. Molecules 8: 13-30. Dadyburjor, D.B. and Z.Y. Liu

  19. A Study on Performance Degradation of PEMFC by Water Freezing

    E-Print Network [OSTI]

    A Study on Performance Degradation of PEMFC by Water Freezing Workshop on Fuel Cell Operation at Sub-Freezing Temperatures Feb. 1-2, 2005 EunAe Cho Fuel Cell Research Center Korea Institute and PEM. Nyquist plots Ionic conductivity #12;Fuel Cell Research Center Conclusions A repetitive freezing

  20. Cancer Stem Cells: Models and Concepts

    E-Print Network [OSTI]

    Brutlag, Doug

    Cancer Stem Cells: Models and Concepts Piero Dalerba, Robert W. Cho, and Michael F. Clarke Stanford c 2007 by Annual Reviews. All rights reserved 0066-4219/07/0218-0267$20.00 Key Words self-renewal by a pathologi- cal counterpart of normal adult stem cells, cancer stem cells. This model, first developed

  1. Baseline Report for the Fort Hood Army Base: September 2003 to October 2004

    E-Print Network [OSTI]

    Haberl, J. S.; Liu, Z.

    2007-09-21

    who helped keep the computers running, the data flowing, and the printers printing at the ESL, including: Mr. Jim Sweeney, Mr. Peter Klima, and Mr. Stephen ONeal, and thanks to Yong Hoon Song, Sopa Visitsak, Soolyeon Cho and Suwon Song for providing...

  2. Low Probability Differentials and the Cryptanalysis of Full-Round CLEFIA-128

    E-Print Network [OSTI]

    International Association for Cryptologic Research (IACR)

    Low Probability Differentials and the Cryptanalysis of Full-Round CLEFIA-128 Sareh Emami2, San Ling far, low probability differentials for the key schedule of block ciphers have been used to exploit particularly cho- sen differentials with a probability as low as 2-128 . CLEFIA-128 has 214

  3. High power rechargeable batteries Paul V. Braun

    E-Print Network [OSTI]

    Braun, Paul

    High power rechargeable batteries Paul V. Braun , Jiung Cho, James H. Pikul, William P. King storage Secondary batteries High energy density High power density Lithium ion battery 3D battery of rechargeable (second- ary) batteries, as this is critical for most applications. As the penetration

  4. RIMS K^oky^uroku Bessatsu B31 (2012), 6177

    E-Print Network [OSTI]

    2012-01-01

    RIMS K^oky^uroku Bessatsu B31 (2012), 6177 Novel Control Principle Based on the Discrepancy Hakodate, 116-2 Kamedanakano-cho, Hakodate 041-8655, Japan 4 Research Institute of Electrical Communication central pattern generators (CPGs) [1, 2], which generates rhythmic signals. Taga et al. presented

  5. Swimming in Issues: A Guide to Dealing with Chinas Water Problems

    E-Print Network [OSTI]

    Morrow, James A.

    Swimming in Issues: A Guide to Dealing with Chinas Water Problems Water, Water, Everywhere February 2, 2013 Control #22551 Seongjin Cho Reed Tillotson Xiaoxu Li Abstract In this paper we present models for projected water needs in China, and examine some of its major problems associated with water

  6. financial report_2012 03_ TRANSFORMING USC

    E-Print Network [OSTI]

    Southern California, University of

    . Caruso Alan I. Casden Ronnie C. Chan Yang Ho Cho Christopher Cox Frank H. Cruz Richard DeBeikes Jr. David McCourt John Mork Jerry W. Neely C. L. Max Nikias, President Robert Padgett Jane Hoffman Popovich of Music Elizabeth M. Daley USC School of Cinematic Arts James G. Ellis USC Marshall School of Business

  7. Nature Macmillan Publishers Ltd 1998 6. James, R. H. & Elderfield, H. Chemistry of ore-forming fluids and mineral formation rates in an active

    E-Print Network [OSTI]

    Nature Macmillan Publishers Ltd 1998 8 6. James, R. H. & Elderfield, H. Chemistry of ore. Lett. 81, 175192 (1986). 13. Mills, R., Thompson, J., Elderfield, H., Hinton, R. W. & Hyslop, E Thegainofthreemitochondrial introns identifies liverworts as the earliest land plants Yin-Long Qiu*, Yangrae Cho, J. Colin Cox

  8. 2009 International SWAT Conference Conference Proceedings

    E-Print Network [OSTI]

    2009-01-01

    -associated bacteria resuspension and settling in SWAT predictions of microbial water quality Jung-Woo Kim, Yakov Pachepsky, Daniel Shelton, Cary Coppock, Kyung Hwa Cho 162-168 Watershed-Scale Fate and Transport of Bacteria Using the Arc-SWAT Model Mehran...

  9. Active Optics Performance Study of the Primary Mirror of the Gemini Telescopes Project

    E-Print Network [OSTI]

    Active Optics Performance Study of the Primary Mirror of the Gemini Telescopes Project Myung K. Cho Optical Sciences Center in the University of Arizona Tucson, AZ 85721 and Gemini Telescopes Project P. O. Box 26732 Tucson, AZ 857266732 Gemini Preprint #9 #12; Active optics performance study of the primary

  10. Convergence in the QM-Only and QM/MM Modeling of Enzymatic Reactions: A Case Study for Acetylene

    E-Print Network [OSTI]

    Liao, Rongzhen

    Convergence in the QM-Only and QM/MM Modeling of Enzymatic Reactions: A Case Study for Acetylene/molecular mechanics (MM) calculations on an enzyme- catalyzed reaction to assess the convergence behavior of QM- only and QM/MM energies with respect to the size of the cho- sen QM region. The QM and MM parts are described

  11. Computational mechanics of molecular systems: Quantifying high-dimensional dynamics by distribution of Poincare recurrence times

    E-Print Network [OSTI]

    Nerukh, Dmitry

    Computational mechanics of molecular systems: Quantifying high- dimensional dynamics computational mechanics as a bridge between deterministic chaos in nonlinear dynamical systems with few degrees-Hakodate, School of Systems Information Science, Department of Complex System, 116-2 Kamedanakano-cho, Hakodate

  12. A Project Report on NP: an Assumption.based NL Plan Inference System that uses Feature Structures

    E-Print Network [OSTI]

    A Project Report on NP: an Assumption.based NL Plan Inference System that uses Feature Structures-cho,Soraku-gun, Kyoto 619-02, Japan myers@atr-la.atr.co.jp Abstract This paper presents a project report on NP

  13. Self-healing Polymer Coatings Paul V. Braun

    E-Print Network [OSTI]

    Braun, Paul

    Self-healing Polymer Coatings Paul V. Braun 1 , Abigail Griffith 1 , Soo Hyoun Cho 1 , and Scott R-healing coatings which autonomically repair and prevent corrosion of the underlying substrate are of particular of these systems however have serious chemical and mechanical limitations preventing their use as coatings. Modern

  14. Multi-PRI Signal Processing for the Terminal Doppler Weather Radar. Part II: RangeVelocity Ambiguity Mitigation

    E-Print Network [OSTI]

    Cho, John Y. N.

    Velocity Ambiguity Mitigation JOHN Y. N. CHO Lincoln Laboratory, Massachusetts Institute of Technology, Lexington of the multi-PRI RV ambiguity mitigation scheme is demonstrated using simulated and real weather radar data, with excellent results. Combined with the adaptive clutter filter, this technique will be used within the larger

  15. Crawling Waves from Radiation Force Excitation ZAEGYOO HAH,1

    E-Print Network [OSTI]

    Parker, Kevin J.

    Crawling Waves from Radiation Force Excitation ZAEGYOO HAH,1 CHRISTOPHER HAZARD,2 YOUNG THUNG CHO1 from focused beams that produce radiation force excitation within the tissue. Some examples are also radiofrequency ablated hepatic lesions in vitro 6,7 to characterize human skeletal muscle in vivo 8, 9

  16. Anodic aluminium oxide catalytic membranes for asymmetric epoxidation{

    E-Print Network [OSTI]

    Anodic aluminium oxide catalytic membranes for asymmetric epoxidation{ So-Hye Cho, Nolan D. Walther, the catalytic membrane reactor configuration confers a significant advantage to oxidation reactions--the use of a catalytic membrane can provide a reactive interface for the oxidation to take place while avoiding long

  17. Proton single voxel spectroscopy (SVS) Ioannis Angelos Giapitzakis1 Alexander Fuchs2 Andreas Hock2 Niklaus Zoelch2 Anke Henning1,2

    E-Print Network [OSTI]

    and frequency fluctuation over time (iv) allows for flexible handling of prior knowledge througout location dedicated close fitting receive array ultra-high field respiratory motion non-water suppressed. 512 water peak acquisitions H2O - Non-water suppressed metabolite cycled 1H MRS: principle H2O Cr Cho

  18. nh Gi Tn Hi Ti Nguyn Thin Nhin do Trn Du Deep Horizon Gim nh bt Nhm Tng ni

    E-Print Network [OSTI]

    vng v c kim. Thit b dy cu vng s v tnh bt phi nhng loi c khc cng nh nhng c th cn qu nh ca l thi gian ngh ngi. Cc d n cng cung cp cho nhng ng dn tham gia hai loi thit b nh bt thay th - tr

  19. Communication Theory JOINT IMPULSE RESPONSE SHORTENING

    E-Print Network [OSTI]

    Adali, Tulay

    channel environments by adjusting the energy and constellation size of each carrier. One implementation of MCM is the Discrete Multi-tone (DMT) system which uses the discrete Fourier transform (DFT) for modulation [2], [3]., DMT has recently been cho- sen as the industry modulation standard for Asymmetri- cal

  20. IEEE TRANSACTIONS ON ELECTRON DEVICES, VOL. 58, NO. 10, OCTOBER 2011 3519 A Focused Asymmetric MetalInsulatorMetal

    E-Print Network [OSTI]

    Dagenais, Mario

    IEEE TRANSACTIONS ON ELECTRON DEVICES, VOL. 58, NO. 10, OCTOBER 2011 3519 A Focused Asymmetric Kwangsik Choi, Filiz Yesilkoy, Geunmin Ryu, Member, IEEE, Si Hyung Cho, Neil Goldsman, Mario Dagenais, Fellow, IEEE, and Martin Peckerar, Fellow, IEEE Abstract--Asymmetric thin-film metalinsulatormetal (MIM

  1. University , Engineering

    E-Print Network [OSTI]

    Zakharov, Leonid E.

    , Princeton Plasma Physics Laboratory Presented at Seminar of Department of Nuclear Engineering Massachusetts{AC020{76{CHO{3073. Leonid E. Zakharov, Department of Nuclear Engineering, MIT , Feb.26, 2001, Cambridge acting on the guide wall. This design concept opens opportunities for nuclear engineers and technologists

  2. Spectra of Comets: Infrared and Radio Regions. J. Crovisier

    E-Print Network [OSTI]

    Demoulin, Pascal

    in the millimetresubmillimetre domain; some of them, like methanol, through many lines. In addition, the 18cm now observed in several comets. Methanol is definitely con tributing, but excess emissions are present at 3.28 m, attributed to aromatics, and around 3.4 m, presumably due to CHO species. Emission

  3. Utility Accrual Real-Time Scheduling for Multiprocessor Embedded Systems

    E-Print Network [OSTI]

    Ravindran, Binoy

    Utility Accrual Real-Time Scheduling for Multiprocessor Embedded Systems Hyeonjoong Cho a Binoy We present the first Utility Accrual (or UA) real-time scheduling algorithm for mul- tiprocessors, called global Multiprocessor Utility Accrual scheduling algorithm (or gMUA). The algorithm considers

  4. Agents on the Web The Sentient Web

    E-Print Network [OSTI]

    Huhns, Michael N.

    Agents on the Web The Sentient Web "I n a startling revelation, a team of uni- versity scientists. In spite of the ominous tone typically cho- sen for dramatic effect, a sentient Web would be more helpful and much easier for people to use. When people find the Web frustrating, it is usual- ly not because

  5. On the Interplay of Parallelization, Program Performance, and Energy Consumption

    E-Print Network [OSTI]

    Scarano, Vittorio

    On the Interplay of Parallelization, Program Performance, and Energy Consumption Sangyeun Cho to either minimize the total energy consumption or minimize the energy-delay product. The impact of static through parallel execution of applications, suppressing the power and energy consumption remains an even

  6. Effects of Exercise and Diet- induced Weight Loss in Overweight/Obese Women on Characterization of Serum/White Blood Cells, microRNAs and Cytokine Gene Transcription

    E-Print Network [OSTI]

    Simbo, Sunday Yamo

    2013-12-11

    .94.4 % body fat) completed a 12-week study (exercise group (EX): n=29; control group (C): n=20). Participants followed an energy-restricted diet (1,200 kcal/d for 1-week and 1,500 kcal/d for 11 weeks; 30% CHO, 45% P, and 25% F) while participating in a 30...

  7. Mathematical Modeling of the Influence of RKIP on the ERK Signaling Pathway

    E-Print Network [OSTI]

    Rostock, Universitt

    Mathematical Modeling of the Influence of RKIP on the ERK Signaling Pathway Kwang-Hyun Cho1*, Sung the influence of the Raf Kinase Inhibitor Pro- tein (RKIP) on the Extracellular signal Regulated Kinase (ERK the simulation the sensitivity of the ERK pathway to variations of initial RKIP and ERK-PP (phosphorylated ERK

  8. Width-tunable pulse generation using four-wave mixing in bismuth based highly nonlinear fiber

    E-Print Network [OSTI]

    Wai, Ping-kong Alexander

    Width-tunable pulse generation using four-wave mixing in bismuth based highly nonlinear fiber-cho, Yokohama 221-8755, Japan Received 15 August 2006; received in revised form 28 February 2007; accepted 5 of a compact and all-fiber based width-tunable pulse gen- erator using four-wave mixing (FWM) effect in only 1

  9. Direct time-domain observation of transition from strong to weak coupling in a semiconductor microcavity

    E-Print Network [OSTI]

    Cao, Hui

    Fluctuation Project, NTT Musashino R&D Center, 3-9-11 Midori-cho, Musashino-shi, Tokyo 180, Japan Hui Cao was used as the local os- cillator wave, the other was used to resonantly excite the microcavity sample- electric transducer PZT scanner. This optical path length modulation generates a sinusoidal signal

  10. Low Beat-Noise, Highly Polarized Tunable Fiber Ring Laser H. L. Liu, H. Y. Tam, W. H. Chung,

    E-Print Network [OSTI]

    Wai, Ping-kong Alexander

    , Hong Kong, China N. Sugimoto Asahi Glass Co., Ltd, 1150 Hazawa-cho, Yokohama 221-8755, Japan Abstract. However, intensity noise from these fiber ring structures, especially beat-noise which is generated beat-noise, polarized traveling wave tunable fiber ring laser. The Bi-EDF is pumped by one 1480 nm

  11. 1104 OPTICS LETTERS / Vol. 25, No. 15 / August 1, 2000 Selective delivery of laser energy to biological tissue

    E-Print Network [OSTI]

    Massachusetts at Lowell, University of

    1104 OPTICS LETTERS / Vol. 25, No. 15 / August 1, 2000 Selective delivery of laser energy and were cho- sen as an example.4,5 Optical energy is delivered into tissue through a contacting optical but below the critical angle for high-index tissues, thus allowing optical energy to be coupled efficiently

  12. Vacuum Calculations in Azimuthally Symmetric Geometry M. S. Chance

    E-Print Network [OSTI]

    energy in the vacuum region or through the continuity requirements for the normal component. The method is based upon using Green's second identity and the method of collocation. As useful byproducts symmetric gap in the Work supported by U.S. Department of Energy Contract No. DE-AC02-76-CHO-3073. #12;shell

  13. Vacuum Calculations in Azimuthally Symmetric Geometry \\Lambda M. S. Chance

    E-Print Network [OSTI]

    the volume integrated perturbed magnetic energy in the vacuum region or through the continuity requirements plasmavacuum boundary. The method is based upon using Green's second identity and the method.S. Department of Energy Contract No. DEAC0276CHO3073. #12; shell since most tokamak devices need to have

  14. Stopping of Light by the Dynamic Tuning of Photonic Crystal Slow Light Device

    E-Print Network [OSTI]

    Baba, Toshihiko

    Stopping of Light by the Dynamic Tuning of Photonic Crystal Slow Light Device Yuji Saito1-cho, Chiyodaku, Tokyo 102-0075, Japan *baba@ynu.ac.jp Abstract: We propose a simple technique of stopping light pulses using a slow-light device based on photonic crystal coupled waveguide (PCCW). Dynamically tuning

  15. Th hai, 21/05/2012, 16:05:28 GMT+7 RSS Newsletter Qung co ng dy nng t lm trang ch 14/05/2012 12:38

    E-Print Network [OSTI]

    vng d n ny, gi l H thng Cm bin ni, c th thay i cch theo di cht lng v dng chy ca nc ti h thng sng SacramentoSan Joaquin. y cng l h thng sng cung cp khong 2/3 lng nc ngt cho tiu bang California

  16. Japan-Korea Workshop 2007, Gifu, Japan Multi-Purpose Plasma (MP2) Facility as

    E-Print Network [OSTI]

    Princeton Plasma Physics Laboratory

    Divertor Simulator B. J. Lee, K. Cho, A. England, T. Lho, J. Yoon, and plasma research team Div. Of Plasma and Development KSTARApplied Technology Research Administration Plasma PhysicsPlasma Physics related withrelated phase Hanbit Device MP2 (Multi Purpose Plasma) Facility Facility for basic plasma physics research

  17. A Prototype English-Japanese Machine Translation System for Translating IBM Computer Manuals

    E-Print Network [OSTI]

    A Prototype English-Japanese Machine Translation System for Translating IBM Computer Manuals TaiJiro Tsutsumi Natural Language Processing Science Institute, IBM Japan, Ltd. 5-19, Sanban-cho, Chlyoda-ku Tokyo developed at the Sci- ence Institute of IBM Japan, Ltd. This MT system cur- rently aims at the translation

  18. ieee transactions on ultrasonics, ferroelectrics, and frequency control, vol. 44, no. 2, march 1997 473 Lung Damage Assessment from Exposure to

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    473 Lung Damage Assessment from Exposure to Pulsed-Wave Ultrasound in the Rabbit, Mouse, and Pig to provide a quantitative assessment of the effect. The specific biological effect used was lung damage and the species cho- sen was the rabbit. This work was initiated, in part, by a study [1] in which lung hemorrhage

  19. Matrix Completion with Noisy Side Information Kai-Yang Chiang

    E-Print Network [OSTI]

    California at Davis, University of

    Matrix Completion with Noisy Side Information Kai-Yang Chiang Cho-Jui Hsieh Inderjit S. Dhillon@ucdavis.edu Abstract We study the matrix completion problem with side information. Side information has been considered in several matrix completion applications, and has been em- pirically shown to be useful in many cases

  20. Biogeosciences, 5, 133139, 2008 www.biogeosciences.net/5/133/2008/

    E-Print Network [OSTI]

    Boyer, Edmond

    radiotracer incuba- tions and lipid extraction methods. We found that phospho- lipid synthesis rates varied that are required to harvest energy and material from the environment. Microbial picoplankton (i.e. plankton . The picoplanktonic community dominates the surface waters of the open ocean (e.g. Cho and Azam, 1990) and is composed

  1. COGNITIVE SCIENCE 14, 179-211 (1990) FindingStructurein Time

    E-Print Network [OSTI]

    Cottrell, Garrison W.

    1990-01-01

    -0076 from the Office of Naval Re- search and contract DAAB-O7-87-C-HO27 from Army Avionics, Ft of motor activity, an important issue is whether the action plan is a literal specification of the output

  2. http://w3.pppl.gov/~ zakharov/030106DEMO.ps

    E-Print Network [OSTI]

    Zakharov, Leonid E.

    PHYSICS LABORATORY PPPL 3 #12; 1 Introduction. Basic objectives of DEMO. Present times for magnetic fusion and their strategy Leonid E. Zakharov, Princeton University , Princeton Plasma Physics Laboratory NSTX Physics{76{CHO{3073. Leonid E. Zakharov, NSTX Physics Meeting, Jan. 06, 2003, PPPL PRINCETON PLASMA PHYSICS

  3. JOURNAL OF GEOPHYSICAL RESEARCH, VOL. ???, XXXX, DOI:10.1029/, Examination of Type II Origin with SOHO/LASCO

    E-Print Network [OSTI]

    JOURNAL OF GEOPHYSICAL RESEARCH, VOL. ???, XXXX, DOI:10.1029/, Examination of Type II Origin.-S. CHO ET AL.: EXAMINATION OF TYPE II ORIGIN Abstract. We examine a possibility that metric-type II solar radio bursts are all caused by CME generated shocks. For this we consider 129 type IIs- flare events

  4. Ultrasonic backscatter coefficient quantitative estimates from Chinese hamster ovary cell pellet biophantoms

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    Ultrasonic backscatter coefficient quantitative estimates from Chinese hamster ovary cell pellet August 2010; accepted 6 August 2010 A cell pellet biophantom technique is introduced, and applied verification purposes. BSC estimates from CHO cell pellet biophantoms of known number density were performed

  5. Design Study of the GNIRS Bracket Structure Optical Sciences Center, University of Arizona and Gemini 8m Telescopes

    E-Print Network [OSTI]

    Design Study of the GNIRS Bracket Structure Myung Cho Optical Sciences Center, University has often been overly conservative. As a classical design, Serrurier truss structures are widely and Engineering Mechanics, University of Arizona, Tucson, AZ 85719 Gemini Preprint # 29 #12;Design Study

  6. Design Study of the GNIRS Bracket Structure Optical Sciences Center, University of Arizona and Gemini 8m Telescopes

    E-Print Network [OSTI]

    Design Study of the GNIRS Bracket Structure Myung Cho Optical Sciences Center, University has often been overly conservative. As a classical design, Serrurier truss structures are widely and Engineering Mechanics, University of Arizona, Tucson, AZ 85719 Gemini Preprint # 29 #12; Design Study

  7. Google:[Leonid http://w3.pppl.gov/~zakharov

    E-Print Network [OSTI]

    Zakharov, Leonid E.

    fusion 1 Leonid E. Zakharov Princeton Plasma Physics Laboratory , MS27 P .O. Box 451, Princeton NJ 085430451 APS DPP2007 Meeting, November 16, 2007, Orlando, Florida 1 This work is supported by US DoE contract No. DE--AC020--76--CHO--3073. PRINCETON PLASMA PHYSICS LABORATORY PPPL #12; Abstract In the physics

  8. Google:[Leonid Zakharov] http://w3.pppl.gov/~zakharov The theory of the failure of magnetic fusion1

    E-Print Network [OSTI]

    Zakharov, Leonid E.

    1 Leonid E. Zakharov Princeton Plasma Physics Laboratory, MS-27 P.O. Box 451, Princeton NJ 08543-0451 APS DPP-2007 Meeting, November 16, 2007, Orlando, Florida 1 This work is supported by US DoE contract No. DEAC02076CHO3073. PRINCETON PLASMA PHYSICS LABORATORY PPPL #12;Abstract In the physics

  9. Detection Probability Modeling for Airport Wind-Shear August 28, 2008

    E-Print Network [OSTI]

    Cho, John Y. N.

    Detection Probability Modeling for Airport Wind-Shear Sensors August 28, 2008 John Y. N. Cho Robert An objective wind-shear detection probability estimation model is developed for radar, lidar, and sensor combinations. The model includes effects of system sensitivity, site-specific wind-shear, clutter, and terrain

  10. Atmos. Chem. Phys., 15, 30453062, 2015 www.atmos-chem-phys.net/15/3045/2015/

    E-Print Network [OSTI]

    Meskhidze, Nicholas

    compounds (OVOCs) are important products of the photo-oxidation of hydrocar- bons. They influence in formaldehyde (HCHO), acetaldehyde (CH3CHO), methyl ethyl ketone (MEK) and methanol were found to be 12.9, 15 Chemical Mechanism version 3.2 (MCM3.2) was applied to evaluate how OVOC production responds to the reduced

  11. Performance Analysis of Multi-Channel Wireless Infrastructure Networks

    E-Print Network [OSTI]

    Ramasubramanian, Srinivasan

    between channels with some tuning delay. A node is a stationary wireless router which is mounted usuallyPerformance Analysis of Multi-Channel Wireless Infrastructure Networks Sangman Cho, Srinivasan, Washington, DC 20052 Abstract--Wireless infrastructure networks that provide ubiq- uitous connectivity

  12. CHNG 5 CHNG TRNH KHI PHC SM XUT: PHT TRIN V NH GI CC GII PHP ...............................................................................................................................................................1

    E-Print Network [OSTI]

    ..............................17 5.3.5 Gii php 3: Gp phn vo Vic Cung cp v Tng cng C hi cho Dch v Gii tr....17 5.3.6 Gii php 3 Lng Mi Trng(CEQ) v vic thc hin Chnh Sch Lut Mi Trng Quc Gia (NEPA) cng hng dn cc t chc nghin cu

  13. i Hc James Cook (JCU) l trng i hc hng u ca c nm trong khu vc vnh ai nhit i.

    E-Print Network [OSTI]

    ma nhit i thuc Vng nhit i m t Wet Tropics cng nh thnh ph quc gia si ng Singapore. Cc thnh ph nhit i v y t cng ng. L trng i hc nghin cu hng u, JCU em li cho sinh vin iu kin c s vt cht tt nht

  14. Heterocyclic small molecule peptidomimetics

    E-Print Network [OSTI]

    Liu, Jing

    2009-05-15

    , Phe, Val, !-Ala 2 H, M R = alkyl estr or polymer suport +Ar-CHO + HS R 2 O H N S OR 2 Aryl R 1 HO 2 C " Batey and coworker prepared of a series of N-terminal 2-iminohydantoin-based peptide heterocycle conjugates via a diverted Edman...

  15. Housing & other information for international students visiting the CEP

    E-Print Network [OSTI]

    Cosmides, Leda

    Housing & other information for international students visiting the CEP General information about housing at UCSB: http://www.housing.ucsb.edu/hchoices/cho-general-info.htm Housing tips for international students: http://www.housing.ucsb.edu/hchoices/international-tips.htm Housing placement

  16. Received 21 Jan 2014 | Accepted 28 Aug 2014 | Published 14 Oct 2014 Ultralow viscosity of carbonate melts

    E-Print Network [OSTI]

    Manning, Craig

    and mobility of carbonate-rich melts in the Earth's mantle is important for understanding the deep carbon cycle of California Los Angeles, 595 Charles Young Drive East, Box 951567, Los Angeles, California 90095, USA. 3 Geodynamics Research Center, Ehime University, 25 Bunkyo-cho, Matsuyama 7908577, Japan. 4 GeoSoilEnviroCARS

  17. Tree and Forestry Science and Biotechnology Abbreviation: Tree For. Sci. Biotech. (TFSB)

    E-Print Network [OSTI]

    Xi, Weimin

    , Andhra University, India M. Mehdi Sharifani, Gorgan University of Agricultural Sciences & Natural Resources, Iran Luke Simon, The Queen's University of Belfast, UK Anoop Kumar Srivastava, National Research Miki cho, Ikenobe 3011-2, P.O. Box 7 761-0799, Japan GSB homepage: www.globalsciencebooks.info Journals

  18. ACCEPTED FOR PUBLICATION IN ELSEVIER COMPUTER NETWORKS JOURNAL, AUGUST 2013 1 Localizing Link Failures in All-Optical Networks

    E-Print Network [OSTI]

    Ramasubramanian, Srinivasan

    have developed methods for localizing failures by observing monitor alarms generated by monitors [3 Failures in All-Optical Networks Using Monitoring Tours Sangman Cho and Srinivasan Ramasubramanian-tours) to uniquely localize all possible failures up to k links in all-optical networks. We establish paths

  19. Ying Xu Curriculum Vitae Address Tepper School of Business, 5000 Forbes Ave,

    E-Print Network [OSTI]

    Sadeh, Norman M.

    , corporate social responsibility in supply chain, energy demand side management Working Papers The Benefit and Information Transparency in Global Supply Chains (with SH. Cho and S. Tayur). Working paper Demand Side Proceedings Multi-agent Coordination for Demand Management with Energy Generation and Storage (with R. Zheng

  20. Corrections COMMENTARY. For the article ``Reprogramming stem cells is a

    E-Print Network [OSTI]

    Chan, Hue Sun

    doi 10.1073 pnas.0810729105 BIOCHEMISTRY. For the article ``Transport of LDL-derived cho- lesterol distinguishes two distinct transport routes from endosomes to the trans-Golgi in human cells. J Cell Biol 180: A cytochemical freeze-fracture study. J Lipid Res 34:11651176. 35. Liscum L (1998) in Intracellular Cholesterol

  1. Chapter 8 -Carbohydrates Hydrates of Carbon: Cm(H2O)n

    E-Print Network [OSTI]

    O'Neil, Joe

    -glyceraldehyde are reference molecules for assignment of stereochemistry (absolute configuration). CH2OH C OHH CHO CH2OH C HHO the same configuration as D-glyceraldehyde. ! = CH2OH OH OH HO O CH2OH D-Fructose CH2OH C O C HHO C C CH2OH

  2. Transport of surface states in the bulk quantum Hall effect Department of Physics, University of California, Santa Barbara, California 93106

    E-Print Network [OSTI]

    Transport of surface states in the bulk quantum Hall effect Sora Cho Department of Physics, University of California, Santa Barbara, California 93106 Leon Balents Institute for Theoretical Physics, University of California, Santa Barbara, California 93106 Matthew P. A. Fisher Institute for Theoretical

  3. AN INTEGRATION TECHNOLOGY FOR LONG DISTANCE LOGISTICS AND SUPPLY CHAIN MANAGEMENT

    E-Print Network [OSTI]

    Peng, Yun

    1 AN INTEGRATION TECHNOLOGY FOR LONG DISTANCE LOGISTICS AND SUPPLY CHAIN MANAGEMENT Hyunbo Cho will continue to grow. That trade depends on many intercontinental, long-distance, logistics partners. Those) ensure interoperability among logistics applications; (2) provide shipment visibility to all trading

  4. Organic solar cells using few-walled carbon nanotubes electrode controlled by the balance between sheet resistance and the transparency

    E-Print Network [OSTI]

    Liu, Jie

    Technology, Hokuryo-cho, Matsue, Shimane 690-0816, Japan Received 6 January 2009; accepted 24 February 2009 to easy solution-processing fabrication and high flexibility. Single-walled CNTs SWNT films on glass or poly ethylene terephthalate PET were investigated.2,3 Theoretically the work function of SWNT 4.85.0 e

  5. Effects of long DNA folding and small RNA stemloop in thermophoresis

    E-Print Network [OSTI]

    Tlusty, Tsvi

    -Ushinomiya-cho, Kyoto 606-8302, Japan; c Japan Science and Technology Agency, PRESTO, Kawaguchi, Saitama 332-0012, Japan; d Department of Complex Systems, Weizmann Institute of Science, Rehovot 76100, Israel; and e of temperature. In an aqueous solution, a PEG polymer suspension is depleted from the hot region and builds

  6. Evaluating Depth Perception of Volumetric Data in Semi-Immersive VR

    E-Print Network [OSTI]

    Ras, Zbigniew W.

    Evaluating Depth Perception of Volumetric Data in Semi-Immersive VR Isaac Cho UNC Charlotte, USA but less for so volumetric data. Volumetric data is characterized by a heavy presence of transparency- ing perception of depth in volumetric data. Our study also suggests that familiarity with 3D games

  7. Evaluating Depth Perception of Volumetric Data in Semi-Immersive VR

    E-Print Network [OSTI]

    Ras, Zbigniew W.

    Evaluating Depth Perception of Volumetric Data in Semi-Immersive VR Isaac Cho Wenwen Dou Zachary volumetric data. This poster present results of an initial formal experiment that examines the effectiveness of various display conditions on depth perception of volumetric data. There is an overall benefit

  8. Stereo and Motion Cues Effect on Depth Perception in Volumetric Data (Technical Report: CVC-UNCC-13-12,

    E-Print Network [OSTI]

    Ras, Zbigniew W.

    Stereo and Motion Cues Effect on Depth Perception in Volumetric Data (Technical Report: CVC-UNCC-13 cues effect on depth judgment of volumetric data," Stereoscopic Displays and Applications XXV (SD&A2014 on Depth Perception of Volumetric Data Isaac Cho, Zachary Wartell, Wenwen Dou, Xiaoyu Wang and William

  9. and INTERNATIONAL ATOMIC ENERGY AGENCYIOP PUBLISHING NUCLEAR FUSION Nucl. Fusion 48 (2008) 024016 (13pp) doi:10.1088/0029-5515/48/2/024016

    E-Print Network [OSTI]

    Solna, Knut

    2008-01-01

    and INTERNATIONAL ATOMIC ENERGY AGENCYIOP PUBLISHING NUCLEAR FUSION Nucl. Fusion 48 (2008) 024016 devices Milan Rajkovi´c1 , Milos Skori´c2 , Knut Sølna3 and Ghassan Antar4 1 Institute of Nuclear Sciences Vinca, Belgrade, Serbia 2 National Institute for Fusion Science, 322-6 Oroshi-cho, Toki 509-5292, Gifu

  10. The insecticide 1,1,1-trichloro-2,2-bis(p-chlorophenyl) ethane (DDT) alters the membrane raft location of the TSH receptor stably expressed in Chinese hamster ovary cells

    SciTech Connect (OSTI)

    De Gregorio, Francesca; Pellegrino, Mario; Picchietti, Simona; Belardinelli, Maria C.; Taddei, Anna Rita; Fausto, Anna Maria; Rossi, Mario; Maggio, Roberto; Giorgi, Franco

    2011-06-01

    DDT is a highly lipophilic molecule known to deplete membrane rafts of their phosphoglycolipid and cholesterol contents. However, we have recently shown that DDT can also alter the thyroid homeostasis by inhibiting TSH receptor (TSHr) internalization. The present study was undertaken to verify whether DDT goitrogenic effects are due to the insecticide acting directly on TSHr or via alteration of the membrane rafts hosting the receptor itself. Our results demonstrate that, in CHO-TSHr transfected cells, TSHr is activated in the presence of TSH, while it is inhibited following DDT exposure. DDT can also reduce the endocytic vesicular traffic, alter the extension of multi-branched microvilli along their plasma membranes and induce TSHr shedding in vesicular forms. To verify whether TSHr displacement might depend on DDT altering the raft constitution of CHO-TSHr cell membranes the extent of TSHr and lipid raft co-localization was examined by confocal microscopy. Evidence shows that receptor/raft co-localization increased significantly upon exposure to TSH, while receptors and lipid rafts become dislodged on opposite cell poles in DDT-exposed CHO-TSHr cells. As a control, under similar culturing conditions, diphenylethylene, which is known to be a lipophilic substance that is structurally related to DDT, did not affect the extent of TSHr and lipid raft co-localization in CHO-TSHr cells treated with TSH. These findings corroborate and extend our view that, in CHO cells, the DDT disrupting action on TSHr is primarily due to the insecticide acting on membranes to deplete their raft cholesterol content, and that the resulting inhibition on TSHr internalization is due to receptor dislodgement from altered raft microdomains of the plasma membrane. - Highlights: >DDT is a pesticide with a severe environmental impact >Epidemiologic correlation exists between exposition to DDT and thyroid dysfunction >DDT is a lipophilic molecule that has been shown to inhibit TSH receptor function >DDT depletes membrane raft cholesterol content and by this way inhibits TSH receptor

  11. Induction and Persistence of Large ?H2AX Foci by High Linear Energy Transfer Radiation in DNA-Dependent protein kinaseDeficient Cells

    SciTech Connect (OSTI)

    Bracalente, Candelaria; Ibaez, Irene L.; Molinari, Beatriz; Palmieri, Mnica; Kreiner, Andrs; Valda, Alejandro; and others

    2013-11-15

    Purpose: To evaluate the cell response to DNA double-strand breaks induced by low and high linear energy transfer (LET) radiations when the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs), an essential protein of the nonhomologous end-joining repair pathway, lacks kinase activity. Methods and Materials: CHO10B2, a Chinese hamster ovary cell line, and its derived radiosensitive mutant cell line, irs-20, lacking DNA-PKcs activity, were evaluated after 0 to 3 Gy of ?-rays, plateau and Bragg peak protons, and lithium beams by clonogenic assay, and as a measurement of double-strand breaks, phosphorylated H2AX (?H2AX) foci number and size were quantified by immunocytofluorescence. Results: Irs-20 exhibited greater radiosensitivity and a higher amount of ?H2AX foci than CHO10B2 at 6 hours after irradiation for all types of radiations. Remarkably, CHO10B2 and irs-20 maintained their difference in radiosensitivity after high-LET radiation. Six hours after low-LET radiations, irs-20 did not reach basal levels of ?H2AX at high doses, whereas CHO10B2 recovered basal levels for all doses. After high-LET radiation, only CHO10B2 exhibited a reduction in ?H2AX foci, but it never reached basal levels. Persistent foci in irs-20 confirmed a repair deficiency. Interestingly, after 30 minutes of high-LET radiation both cell lines exhibited large foci (size >0.9 ?m{sup 2}) related to the damage nature, whereas at 6 hours irs-20 showed a higher amount of large foci than CHO10B2, with a 7-fold increase at 3 Gy, that could also be associated to radiosensitivity. Conclusions: We demonstrated, for the first time, an association between deficient DNA-PKcs activity and not only high levels of H2AX phosphorylation but also persistence and size increase of ?H2AX foci after high-LET irradiation.

  12. Characterization of microchip capillary electrophoresis systems coupled to microdialysis for on-line monitoring

    E-Print Network [OSTI]

    Nandi, P.; Suzuki, N.; Lunte, Susan M.

    2006-10-25

    secs 5 secs F l uoresce nce U n i t Minute 7.95 mM Arg 2 4 6 8 10 12 Fl uor escence U n i t Minute 035810 Fl uor e scence U n i t Minute CHO CHO RNH 2 -X+ + NR X Naphthalene?2,3?dicarboxaldehyde ?Reduction/?absence?of?electrokinetic sampling...01234 250 nM 100 nM 25 nM Blank F l uo re sce nc e U n i t Minute F l uo re sce nc e U n i t Microdialysis DEVELOPMENT?OF?A?MICRODIALYSIS?MICROCHIP?CE?SYSTEM? FOR?ON?LINE?MONITORING Pradyot Nandi,?Nobuyuki?Suzuki,?Susan?M.?Lunte Department...

  13. Search for charged Higgs bosons in top quark decays

    E-Print Network [OSTI]

    Baringer, Philip S.; Bean, Alice; Clutter, Justace Randall; Moulik, Tania; Wilson, Graham Wallace; DØ Collaboration; Abazov, V. M.; Abbott, B.; Abolins, M.; Acharya, B. S.; Adams, M.; Adams, T.; Aguilo, E.; Ahsan, M.

    2009-12-07

    . Carrera aw, W. Carvalho c, B.C.K. Casey ax, H. Castilla-Valdez ah, . Chakrabarti bt, D. Chakraborty az, K.M. Chan bc, A. Chandra av, E. Cheu at, D.K. Cho bj, S.W. Cho af, . Choi ag, B. Choudhary ac, T. Christoudias ar, S. Cihangir ax, D. Claes bo, J.... Gadfort br, .F. Galea aj, A. Garcia-Bellido bs, V. Gavrilov al, P. Gaym, W. Geist s, W. Geng o,bm, C.E. Gerber ay, . Gershtein aw,2, D. Gillberg f, G. Ginther ax,bs, B. Gmez h, A. Goussiou cd, P.D. Grannis bt, S. Greder s, . Greenlee ax, Z.D. Greenwood bh...

  14. Thermodynamics of site-specific small molecular ion interactions with DNA duplex: a molecular dynamics study

    E-Print Network [OSTI]

    Ghosh, Soumadwip; Chakrabarti, Rajarshi

    2015-01-01

    The stability and dynamics of a double-stranded DNA (dsDNA) is affected by the preferential occupancy of small monovalent molecular ions. Small metal and molecular ions such as sodium and alkyl ammonium have crucial biological functions in human body, affect the thermodynamic stability of the duplex DNA and exhibit preferential binding. Here, using atomistic molecular dynamics simulations we investigate the preferential binding of metal ion such as Na+ and molecular ions such as tetramethyl ammonium (TMA+) and 2-hydroxy-N,N,N-trimethylethanaminium (CHO+) to double stranded DNA. The thermodynamic driving force for a particular molecular ion- DNA interaction is determined by decomposing the free energy of binding into its entropic and enthalpic contributions. Our simulations show that each of these molecular ions preferentially binds to the minor groove of the DNA and the extent of binding is highest for CHO+. The ion binding processes are found to be entropically favourable. In addition, the contribution of hy...

  15. 2012-2013 CDM Club Officer List Alpha Omega Dental Fraternity

    E-Print Network [OSTI]

    Grishok, Alla

    2nd Year Class Rep: Sara Dworkin 3rd Year Class Rep: Michael Shapiro 4th Year Class Rep: Eileen Chun Social Chair: Bethany Wong 4th year rep: Jenny Sun 3rd year rep: Wei King 2nd year rep: Justin Maneevese 4th Year Rep: Joonseok Cho 3rd Year Rep: Wesley Choi 2nd Year Rep: Jenny Xun Chen 1st year rep

  16. SU-E-I-46: Sample-Size Dependence of Model Observers for Estimating Low-Contrast Detection Performance From CT Images

    SciTech Connect (OSTI)

    Reiser, I; Lu, Z [University of Chicago, Chicago, IL (United States)

    2014-06-01

    Purpose: Recently, task-based assessment of diagnostic CT systems has attracted much attention. Detection task performance can be estimated using human observers, or mathematical observer models. While most models are well established, considerable bias can be introduced when performance is estimated from a limited number of image samples. Thus, the purpose of this work was to assess the effect of sample size on bias and uncertainty of two channelized Hotelling observers and a template-matching observer. Methods: The image data used for this study consisted of 100 signal-present and 100 signal-absent regions-of-interest, which were extracted from CT slices. The experimental conditions included two signal sizes and five different x-ray beam current settings (mAs). Human observer performance for these images was determined in 2-alternative forced choice experiments. These data were provided by the Mayo clinic in Rochester, MN. Detection performance was estimated from three observer models, including channelized Hotelling observers (CHO) with Gabor or Laguerre-Gauss (LG) channels, and a template-matching observer (TM). Different sample sizes were generated by randomly selecting a subset of image pairs, (N=20,40,60,80). Observer performance was quantified as proportion of correct responses (PC). Bias was quantified as the relative difference of PC for 20 and 80 image pairs. Results: For n=100, all observer models predicted human performance across mAs and signal sizes. Bias was 23% for CHO (Gabor), 7% for CHO (LG), and 3% for TM. The relative standard deviation, ?(PC)/PC at N=20 was highest for the TM observer (11%) and lowest for the CHO (Gabor) observer (5%). Conclusion: In order to make image quality assessment feasible in the clinical practice, a statistically efficient observer model, that can predict performance from few samples, is needed. Our results identified two observer models that may be suited for this task.

  17. Gene mapping of bovine phosphoribosylglycinamide synthetase (PRGS) and phosphoribosylaminoimidazole synthetase (PAIS) in hybrid somatic cells

    E-Print Network [OSTI]

    McAvin, James Charles

    1986-01-01

    glycol induced fusion of PRGS and PAIS deficient Chinese hamster ovary cells, CHO-Kl ade C and ade G, respectively, with pezipheral leucocytes of normal cattle. When cultuzed in Ham's F12D selective medium, the lack of an exogenous supplement... kinase (Tk) gene expression [15, 16]. The fusion product contained unstable human-mouse hybrid cells which segregated human chromosomes, selectively retaining only the complementary human chromosome carrying the locus for Tk gene expression...

  18. A Three-layered Conceptual Framework of Data Mining

    E-Print Network [OSTI]

    Yao, Yiyu

    A Three-layered Conceptual Framework of Data Mining Y.Y. Yao1 , N. Zhong2 and Y. Zhao1 1 Department-Cho, Maebashi 371, Japan E-mail: zhong@maebashi-it.ac.jp Summary. The study of the foundations of data mining may be viewed as a scien- tific inquiry into the nature of data mining and the scope of data mining

  19. All optical on-off switching using bismuth-based highly nonlinear fiber

    E-Print Network [OSTI]

    Wai, Ping-kong Alexander

    the idlers generated by the four wave mixing effect. When the control signal is low, i.e. the OFF state: enwai@polyu.edu.hk N. Sugimoto Asahi Glass Co., Ltd, 1150 Hazawa-cho, Yokohama 221-8755, Japan Abstract: We have demonstrated all-optical on-off switching at 10 Gbit/s using four-wave mixing in only 1.9 m

  20. Development of a High-Performance Office Building Simulation Model for a Hot and Humid Climate

    E-Print Network [OSTI]

    Cho, S.; Haberl, J.

    2009-01-01

    applicable to office buildings in hot and humid climates and to develop a high-performance (maximum energy-efficient) building model that only uses technologies readily available in the contemporary market. The high-performance model showed 48% total... HIGH-PERFORMANCE OFFICE BUILDING SIMULATION MODEL FOR A HOT AND HUMID CLIMATE Soolyeon Cho1 and Jeff S. Haberl2 1The Catholic University of America, Washington, D.C., USA 2Texas A&M University, College Station, TX, USA ABSTRACT...

  1. Recommendations for 15% Above-Code Energy Efficiency Measures for Commercial Office Building

    E-Print Network [OSTI]

    Cho, S.; Mukhopadhyay, J.; Culp, C.; Haberl, J.; Yazdani, B.

    2007-01-01

    FOR 15% ABOVE-CODE ENERGY EFFICIENCY MEASURES FOR COMMERCIAL OFFICE BUILDINGS Soolyeon Cho Graduate Research Assistant Jaya Mukhopadhyay Research Associate Charles Culp, Ph.D., P.E. Associate Director Jeff Haberl, Ph.D., P.E. Associate Director... Bahman Yazdani, P.E. Associate Director Energy Systems Laboratory Texas Engineering Experiment Station Texas A&M University System ACKNOWLEDGEMENTS Faculty/Staff: Tom Fitzpatrick, Don Gilman, Mushtaq Ahmed, Betty Liu, Juan-Carlos Baltazar, Sherrie...

  2. n ung ung cach, Sng lanh manh

    E-Print Network [OSTI]

    Shen, Jun

    trc khi nu) Tht g (gi li lp da khi nu) Tht tai heo, xng c, chn, tht thn, tht lng Lp xng heo, tht ch cao, cht gy bo ph, v cholesterol. Nhng thc phm o co th lm tng lng m trong mu v dn n bnh tim Dung ti, gng, t, hoc x tng thm mui v cho mon n thay v bt ngt v nc mm S dung s lng nh bt canh, nc

  3. ES.1 Tm Tt Tng Quan ES.1.1 Gii thiu

    E-Print Network [OSTI]

    chm xung Vnh Mexico (Vnh). Tai nn dn n trn mt lng du ln cha tng thy v nhng th khc t gin khoan v (sau y s gi l "S c Trn du", ni chung c cc hot ng nhm ng ph vi lng du trn) Ngoi ra, hn 1 triu gallon cc cht phn tn1 c dng cho vng bin thuc khu vc du trn nhm phn tn lng du trn. Mt lng khng

  4. M thanh ton 4310-55 [FWS-R4-FHC-2013-N108; [FVHC98130406900-XXX-FF04G01000

    E-Print Network [OSTI]

    lng cha tng c du v thi khc t cc gin khoan v t u ging khoan trn y bin. Deepwater Horizon trn trn. Mt s lng cha xc nh kh t nhin cng c pht hnh cho mi trng nh l kt qu ca v trn du. Ngi c y gian c bn (cht lng v iu kin c th tn ti nu s c trn du khng xy ra ti nguyn) hon tt. Cn c cc

  5. (E)-4-[(4-nitrophenyl)diazenyl]phenyl anthracene-9-carboxylate.

    SciTech Connect (OSTI)

    Vance, Andrew L.; Zifer, Thomas; Nichol, Jessica L.; Rodriguez, Mark Andrew; Leonard, Francois Leonard; Wong, Bryan Matthew

    2008-10-01

    In the title compound, C{sub 27}H{sub 17}N{sub 3}O{sub 4}, the azo group displays a trans conformation and the dihedral angles between the central benzene ring and the pendant anthracene and nitrobenzene rings are 82.94 (7) and 7.30 (9){sup o}, respectively. In the crystal structure, weak C-H...O hydrogen bonds, likely associated with a dipole moment present on the molecule, help to consolidate the packing.

  6. Exploiting algal NADPH oxidase for biophotovoltaic energy

    E-Print Network [OSTI]

    Anderson, Alexander; Laohavisit, Anuphon; Blaby, Ian K.; Bombelli, Paolo; Howe, Christopher J.; Merchant, Sabeeha S.; Davies, Julia M.; Smith, Alison G.

    2015-01-29

    oxidases are important for superoxide anion production and open avenues for optimizing the biological component of these devices. Introduction Renewable power sources such as wind farms, solar panels or hydro turbines are now in relatively widespread use... , yet the feasibility of these to replace fossil fuels is uncertain due to their higher cost and lower energy density (Cho, 2010). Therefore, in the past decade, there has been a considerable shift in research focus into harvesting energy from high...

  7. Stationary Magnetic Perturbations (`Locked Modes') and Edge Phenomena in TFTR Tokamak1

    E-Print Network [OSTI]

    Budny, Robert

    . on Plasma Physics and Nuclear Fusion, Toki City, Japan, Nov. 28 - Dec. 1, 1995, Paper T7-I4. #12;APS-DPP97. Takahashi, E. Fredrickson, K. McGuire, and A. Ramsey Princeton Plasma Physics Laboratroy, PrincetonAC0276CHO3073 2 Several types of SMP's were reported earlier -- APS DPP, 1994(6R28), 1995(9P29

  8. Molecular Biology of the Cell Vol. 21, 43614372, December 15, 2010

    E-Print Network [OSTI]

    Fisk, Harold A.

    and Gonczy, 2003), Sas-5 (Delattre et al., 2004), and Sas-6 (Leidel et al., 2005). While there is no apparent., 2008), PLK4 (Habedanck et al., 2005), CPAP/CENP-J (Cho et al., 2006), and Hs-Sas6 (Strnad et al., 2007, the recruitment of HsSas-6 to the site of centriole assembly requires Plk4 (Habedanck et al., 2005), and CPAP

  9. SINGLE BUNCH COLLECTIVE EFFECTS IN MUON COLLIDERS Wen-Hao Cheng, Andrew M. Sessler, Jonathan S. Wurtele

    E-Print Network [OSTI]

    Wurtele, Jonathan

    experiences can be modeled as having two parts, one is due to the radio frequency (rf) cavities, and the other of Energy under contract No. EDDEFG-03-95ER-40936, DE-AC03-76SF00098 and DE-AC02- 76CHO3000 where Krf(z) = e the impacts and the cures of collective instabilities for the muon collider. Some important simula- tion

  10. Pour obtenir le grade de DOCTEUR DE L'UNIVERSIT DE GRENOBLE

    E-Print Network [OSTI]

    cho em nhng kinh nghim v cuc sng cng nh trong hc tp và nghiên cu, cám n các anh ã chia s vi em nhng nm tháng y ý ngha ti Grenoble này. Cm n anh ch em trong gia ình in ti Grenoble cng nh trên toàn nc Pháp vì

  11. Trang chnh Nn coi trang Web

    E-Print Network [OSTI]

    Wenseleers, Tom

    bnh vc quyt nh ca tng thng Berlusconi, ngay c Lin on Y S Ta Thnh cng ln ting tn ng vic cc bnh nh cng lu hn trong c, mc d trn nguyn tc, tr nh ca c hai loi ny hot ng ging nhau. l kt lun bn tri hay bn phi. Mc d thc hin th nghim mi loi ch vi 2 con vt nhng cc chuyn gia cng cho rng kt

  12. Thng 9, 2011 Xu t b n b i O ce of International A airs M i thng tin trong t ri ny u c trn m ng. c thng tin chi ti t v c p nh t, xin vui lng

    E-Print Network [OSTI]

    Wu, Yih-Min

    ng. c thng tin chi ti t v c p nh t, xin vui lng tra c u t i website c a chng ti : http Loan Chng trnh o t o c p b ng cho sinh vin qu c t Lin h v i chng ti International Student Taiwan University ( i h c qu c gia i Loan) Room 419, 4F, 2nd Administration Building (Phng 419, T ng 4

  13. Nome Issue 11

    E-Print Network [OSTI]

    Multiple Contributors

    1988-01-01

    '. . enzo' c acid (PARA)s 20 mgI inositol~ 1000 mgJ methionine~ 7. 5 gmJ gIycine~ 4. 0 gmJ Delstorol (vitauIn D3 ~ 7. 5 gmJ alpha tocopheryl ace ate~ 6 mg J vitamin A (P~rnadry)~ 10s 000 units/gm, ( 1 gm I vitamin P 12~ 30 gamma I cho lire s 2000 mg I...

  14. Abstract Interpretation patrick cousot

    E-Print Network [OSTI]

    Cousot, Patrick

    specific abstract seman tics domain D ] and an abstract seman tics S ] 2 L 7! D ] which is designed in tuitively seman tics S and an approximation ff are cho sen, one can derive the best choice for the corresponding of a tracebased seman tics by a relational/denotational seman tics: ff(P ) def = fhs 0 ; s n i j s 0 s 1

  15. Water and acetaldehyde in HH212: The first hot corino in Orion

    E-Print Network [OSTI]

    Codella, C; Cabrit, S; Podio, L; Bachiller, R; Fontani, F; Gusdorf, A; Lefloch, B; Leurini, S; Tafalla, M

    2016-01-01

    Aims: Using the unprecedented combination of high resolution and sensitivity offered by ALMA, we aim to investigate whether and how hot corinos, circumstellar disks, and ejected gas are related in young solar-mass protostars. Methods: We observed CH$_3$CHO and deuterated water (HDO) high-excitation ($E_{\\rm u}$ up to 335 K) lines towards the Sun-like protostar HH212--MM1. Results: For the first time, we have obtained images of CH$_3$CHO and HDO emission in the inner $\\simeq$ 100 AU of HH212. The multifrequency line analysis allows us to contrain the density ($\\geq$ 10$^{7}$ cm$^{-3}$), temperature ($\\simeq$ 100 K), and CH$_3$CHO abundance ($\\simeq$ 0.2--2 $\\times$ 10$^{-9}$) of the emitting region. The HDO profile is asymmetric at low velocities ($\\leq$ 2 km s$^{-1}$ from $V_{\\rm sys}$). If the HDO line is optically thick, this points to an extremely small ($\\sim$ 20--40 AU) and dense ($\\ge$ 10$^{9}$ cm$^{-3}$) emitting region. Conclusions: We report the first detection of a hot corino in Orion. The HDO asymm...

  16. Functionalized polyfluorenes for use in optoelectronic devices

    DOE Patents [OSTI]

    Chichak, Kelly Scott (Clifton Park, NY); Lewis, Larry Neil (Scotia, NY); Cella, James Anthony (Clifton Park, NY); Shiang, Joseph John (Niskayuna, NY)

    2011-11-08

    The present invention relates to process comprising reacting a polyfluorenes comprising at least one structural group of formula I ##STR00001## with an iridium (III) compound of formula II ##STR00002## wherein R.sup.1 and R.sup.2 are independently alkyl, substituted alkyl, aryl, substituted aryl or a combination thereof; R.sup.5is H or CHO; R.sup.3 and R.sup.4 are independently hydrogen, alkyl, substituted alkyl, aryl, substituted aryl or a combination thereof; R.sup.11 and R.sup.12 taken together form a substituted or unsubstituted monocyclic or bicyclic heteroaromatic ring; R.sup.13 is independently at each occurrence halo, nitro, hydroxy, amino, alkyl, aryl, arylalkyl, alkoxy, substituted alkoxy, substituted alkyl, substituted aryl, or substituted arylalkyl; Ar is aryl, heteroaryl, substituted aryl, substituted heteroaryl, or a combination thereof; X is selected from a direct bond, alky, substituted alkyl, and combinations thereof; Y is CHO or NH.sub.2; Z is CHO or NH.sub.2 where Z does not equal Y; and p is 0, 1 or 2. The invention also relates to the polyfluorenes, which are products of the reaction, and the use of the polyfluorenes in optoelectronic devices.

  17. Amperometric Choline Biosensor Fabricated through Electrostatic Assembly of Bienzyme/Polyelectrolyte Hybrid Layers on Carbon Nanotubes

    SciTech Connect (OSTI)

    Wang, Jun; Liu, Guodong; Lin, Yuehe

    2006-03-01

    We report a flow injection amperometric choline biosensors based on the electrostatic assembly of an enzyme of choline oxidase (ChO) and a bi-enzyme of ChO and horseradish peroxidase (HRP) onto multi-wall carbon nanotubes (MWCNT) modified glassy carbon (GC) electrodes. These choline biosensors were fabricated by immobilization of enzymes on the negatively charged MWCNT surface through alternatively assembling a cationic polydiallydiimethylammonium chloride (PDDA) layer and an enzyme layer. Using this layer-by-layer assembling approach, bioactive nanocomposite film of a PDDA/ChO/PDDA/HRP/PDDA/CNT (ChO/HRP/CNT) and a PDDA/ChO/PDDA/ CNT (ChO/ CNT) were fabricated on GC surface, respectively. Owning to the electrocatalytic effect of carbon nanotubes, the measurement of faradic responses resulting from enzymatic reactions has been realized at low potential with acceptable sensitivity. It is found the ChO/HRP/CNT biosensor is more sensitive than the ChO/CNT one. Experimental parameters affecting the sensitivity of biosensors, e.g. applied potential, flow rate, etc. were optimized and potential interference was examined. The response time for this choline biosensor is fast (less than a few seconds). The linear range of detection for the choline biosensor is from 5 x 10-5 to 5 x 10-3 M and the detection limit is determined to be about 1.0 x 10-5 M.

  18. Mapping analysis of scaffold/matrix attachment regions (s/MARs) from two different mammalian cell lines

    SciTech Connect (OSTI)

    Pilus, Nur Shazwani Mohd; Ahmad, Azrin; Yusof, Nurul Yuziana Mohd [School of Bioscience and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor (Malaysia); Johari, Norazfa [Department of Chemical and Process Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor (Malaysia)

    2014-09-03

    Scaffold/matrix attachment regions (S/MARs) are potential element that can be integrated into expression vector to increase expression of recombinant protein. Many studies on S/MAR have been done but none has revealed the distribution of S/MAR in a genome. In this study, we have isolated S/MAR sequences from HEK293 and Chinese hamster ovary cell lines (CHO DG44) using two different methods utilizing 2 M NaCl and lithium-3,5-diiodosalicylate (LIS). The isolated S/MARs were sequenced using Next Generation Sequencing (NGS) platform. Based on reference mapping analysis against human genome database, a total of 8,994,856 and 8,412,672 contigs of S/MAR sequences were retrieved from 2M NaCl and LIS extraction of HEK293 respectively. On the other hand, reference mapping analysis of S/MAR derived from CHO DG44 against our own CHO DG44 database have generated a total of 7,204,348 and 4,672,913 contigs from 2 M NaCl and LIS extraction method respectively.

  19. South Korean "New Wild Geese" Mothers Studying in the U.S.:Balancing between Studenthood and Motherhood

    E-Print Network [OSTI]

    Lee, Ji-Yeon

    2013-05-31

    of childrens education began to appear around 1993. It was at this time that Kim Young Sams government implemented a new policy of globalization and planned compulsory English language education as early as the third grade. A number of K-12 Korean...-cultural meanings of these Korean transnational families (Cho Uhn 2004, 2005, 2008; Ahn Kwang-bok 2004), the fathers left in Korea (Choi Yang-Suk 2008, Kim Sung-Sook 2006, Uhm Myong-yong 2002), and the childrens lives as foreign students studying overseas...

  20. Fire, Sacrifice, and Social Change: The Rhetoric of Self-Immolation

    E-Print Network [OSTI]

    Neville-Shepard, Meredith Diane

    2014-08-31

    communicable [experience] of all, other scholars argue the exact opposite. 40 For instance, Young Cheon Cho directly refuted Arendts idea that the body is perhaps the only experience which we are unable to transform into a shape fit for 11 public... sacrifice of wealth. Therefore, after burning so long and bright, the Medicine King was immediately reborn again in the realm of the Buddha Pure and Bright 23 Excellence of the Sun and Moon.12 Scripture stated, This, young man of good family...

  1. An investigation of the trajectories of rotating thunderstorms: a numerical experiment.

    E-Print Network [OSTI]

    Veazey, Don Russell

    1968-01-01

    points of the g-hr forecast, . ??, ~ . . . , . ~ . , The trajectory of the Case 3 storm center. See Fig, 13 for other details. Note that the hard-core portion of the storm was located in the southwest quadrant of the mar g88. n e cho ~ ~ ~ ~ ~ o... ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ o 44 Ths trajectory oi' the Case 0 storm center. See Pig, 15 for other Let's. . i ~ ~ ~ . ~ ~ ~ ~ ~ 0 ~ ~ ~ ~ ~ ~ 45 The trajectory of the Case D storm center, See Pig. 15 for other details, In this case the hard-core portion of Qu storm ~i...

  2. Synthesis and crystal structure studies of ethyl 5-methyl-1, 3-diphenyl-1H-pyrazole-4-carboxylate

    SciTech Connect (OSTI)

    Chandra,; Babu, E. A. Jithesh; Mahendra, M.; Srikantamurthy, N.; Umesha, K. B.

    2014-04-24

    The title compound, C{sub 19}H{sub 18}N{sub 2}O{sub 2}, was investigated by single crystal X-ray diffraction method. It crystallizes in monoclinic class under the space group P2{sub 1}/c with cell parameters a= 8.4593(4) , b=15.6284(6) , c=12.4579(5) , ?=90, ?=98.241(3), ?=90 and Z=2. The ethoxycarbonyl group is slightly twisted from the pyrazole ring, and adopts syn-periplanar conformation. The crystal structure is stabilized by intermolecular C-H.O hydrogen bonds, which help in stabilizing the crystal structure.

  3. A new sociolinguistic taxonomy, cookbook, and immigrant communities

    E-Print Network [OSTI]

    Asahi, Yoshiyuki

    2010-01-01

    community more than 100 years old. Diaspora study, on the other hand, addresses one society, which arose at the beginning of the twentieth century. Sakhalin Island is more diverse in a sociolinguistic sense since this island has received a number... Centralis 1/2010 Yoshiyuki Asahi Table 1 Categories of the two communities (1) New Town Study (2) Diaspora Study Seishin New Town Hazetani cho Sakhalin Population c.60,000 c.2,000 c.2,000 Major Industry Service industry, Specialist, Teachers Agriculture...

  4. The effects of varying plant densities on water yield and erosion as determined from a lysimeter study in central Arizona

    E-Print Network [OSTI]

    Gary, Howard Lynnwood

    1961-01-01

    ' /. JLCR5 Qf pBFR1' vlR8114 January 19GX m I o 0 I Xn presenting the material that follows, the anther hae tried to emphasizes gssntitatkccs meaemcmmnte, Xt is folly realised that in many oases the data prescnxbed are not mhoUy eatisfaotory... valuesa Xn the early 1980's a need for a ressaroh unit to wofh out more River ?atsrshsd was reoognised, and ths gisrra dnoha Pxperimsmtal Pater sheds were estab&shed im 1888 (44). C'ho empsrljmfntal program o'f these watersheds inoludes studies...

  5. Chung Qui Ch T i Cantor Ng Quang Hng

    E-Print Network [OSTI]

    Ngo, Hung Q.

    USD [20] và danh ti ng i vào l ch s khoa h c. Cng nh bài toán Fermat l n, b n thân câu tr l i cho bài này [11], thách hn n a th k nghiên c u c a các 1 #12;k s và khoa h c gia hàng u. Ng c l i, cng không

  6. Leibniz Universitt Hannover Leibniz Universitt Hannover (LUH hay vi tn y Gottfried Wilhelm

    E-Print Network [OSTI]

    Nejdl, Wolfgang

    trng cho gii trí Hannover, ngoài ra cng là thc n tinh thn ca mi ngi dân. Cánh rng bo ph khp thành ph Hannover vi các trng H hàng u càng ngày c tng cng và các tho thun hp tác c c th hoá hn. Có hn 30 sinh viên

  7. ENGLISH l TuanVietNam.Net l VieTimes l Lm bo cng VietNamNet l Tr c Tuy n l Th H CNTT -Vi n thng

    E-Print Network [OSTI]

    Lummaa, Virpi

    25%, ng th i c h i l y ch ng cng gi m i 15%... l k t qu nghin c u c a cc nh khoa h c thu c Tr v i nh ng b gi sinh i cng v i m t b gi khc (song sinh n ). ng th i, nh ng b gi cng c c h tr ng thnh. B cho bi t vi c phi nhi m v i testosterone m c cao trong t cung cng c th lm tng nguy

  8. nh gi Tn tht Ti nguyn Thin nhin Trn du Deepwater Horizon D n Ci thin Tri nghim Ngi i B v Xe

    E-Print Network [OSTI]

    IVProposedEarlyRestorationProject M T D N D n ci thin vic s dng ng dnh cho xe p v ngi i b ti Davis Bayou bao gm tng cng ci thin qua khi khong 10.000 c dn chuyn n cc vng ln cn. Ngi s dng tuyn ng giao thng cng cng ny bao gm sung c quy hoch v tng chn s c xy dng nhng ni c ng c nng ln. D n cng bao gm vic xy dng bin bo

  9. An environmental study of the subsurface Miocene of Brazoria and Galveston counties, Texas

    E-Print Network [OSTI]

    Linder, Henry Darrell

    1962-01-01

    ~ 16 Vertical Djstrihution of Environments. ~. . . . . 19 Tezacoo Es Kainer, Hoo 1 ~ ~ o r e ~ y r ~ ~ ~ 19 Humble, Houston FermI and Development Company Hoe 1 5 ~ . a ~ ~ r' a ~ ~ ~ a a a o ~ ~ . e ~ ~ ~ 22 TABLE OF CGHTBHTS cont'd Rage Pan... American, Houston F~as and Development CoeeQg Haa 1-D 'e ~ ~ ~ ~ a a ~ ' ~ ~ ~ ~ ~ e 24 ?, Amer&de Houston Farms ~? d Development COBP&nF HOa 2 a ~ a a ~ ~ ~ ~ ~ ~ . ~ ~ e a ' ~ e '26 Cho~line State Tract ', A" 1 Ho. 1 , . . . . . 27 Shell, St:te Tract...

  10. Electronic States and Optical Transitions in Bulk and Quantum Well Structures of III-V Compound Semiconductors

    E-Print Network [OSTI]

    Cho, Yong Hee 1976-

    2011-05-06

    of GaInAs/AlInAs double quantum wells shown in Fig. 4-4, is followed on the lightly doped InP cladding which is positioned on the top of substrate. Highly doped 0.4 ?m-thick InP contact layer and Au contact are sequentially stacked above... AND OPTICAL TRANSITIONS IN BULK AND QUANTUM WELL STRUCTURES OF III-V COMPOUND SEMICONDUCTORS A Dissertation by YONG HEE CHO Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements...

  11. Basketball - Womens - 1

    E-Print Network [OSTI]

    Unknown

    2006-01-01

    guidance. I leave Texas AIM with fond of memories of the people I met there, including Cindy Cho, Jai-Hoon Kim, and Nohpill Park. I thank them all and wish them the best in the future. I thank my parents, Chulyoung Yoon and Youngsoon Lee, for their love...-case end-to-end delay and on the worst-case delay jittez foz packets of the connection. Other parameters may be specified as well, such as packet loss rate, deadline miss rate, but we will not further address them in this discussion. The desired delivery...

  12. The Effect of Point Velocity Probe Size on Groundwater Velocity Estimation in Noncohesive Sediments

    E-Print Network [OSTI]

    Burris, Natalie Lynn

    2014-12-31

    .7 References Alden, A. S. and C. L. Munster. 1997. Field Test of the In Situ Permeable Ground Water Flow Sensor. Ground Water Monitoring & Remediation 17 no. 4: 81-88. Annable, M. D., Hatfield, K., Cho, J., Klammler, H., Parker, B.L., Cherry, J.A., and P.S.C.../Lewis Publishers. Devlin, J.F. and C.D. McElwee. 2007. Effects of Measurement Error on Horizontal Hydraulic Gradient Estimates. Ground Water 45 no. 1:62-73. Devlin, J.F., Tsoflias, G., McGlashan, M., and P. Schillig. 2009. An Inexpensive Multilevel Array...

  13. Fragile-to-Strong Crossover in Supercooled Liquid Ag-In-Sb-Te Studied by Ultrafast Calorimetry

    E-Print Network [OSTI]

    Orava, Jiri; Hewak, Daniel W.; Greer, A. Lindsay

    2015-07-14

    by Zhuravlev and Schick.[49] Samples were heated at 50 K s?1 to 40 000 K s?1 under a nitrogen flow of 20 cm3 min?1. Temperature calibration was performed, at different heating rates, by measuring the onset of melting of a 1 ?g sample of indium; the thermal... , 22457. 25 [48] J.-Y. Cho, D. Kim, Y.-J. Park, T.-Y. Yang, Y.-Y. Lee, Y.-C. Joo, Acta Mater. 2015 94, 143. [49] a) E. Zhuravlev, C. Schick, Thermochim. Acta 2010, 505, 1; b) E. Zhuravlev, C. Schick, Thermochim. Acta 2010, 505, 14. [50] J. C...

  14. Hunter Building, Kelburn Campus VICTORIA UNIVERSITY

    E-Print Network [OSTI]

    Frean, Marcus

    Trng i hc Tng Hp Victoria gm có bn c s ti Wellington, New Zealand. Wellington là th ô và cng là trung tâm vn hóa ca New Zealand. ây là mt ni hc tp lý tng giành cho sinh viên quc t và cng là mt thành ph i Cng + Khoa Hc Vt Lý + Toán hc + Thit k + Lch S New Zealand Hin i * + Khoa Hc Sinh Hc. *Sinh viên

  15. Where Businesses Thrive: Predicting the Impact of the Olympic Games on Local Retailers through Location-based Services Data

    E-Print Network [OSTI]

    Georgiev, Petko; Noulas, Anastasios; Mascolo, Cecilia

    2014-05-16

    . The Olympic-related venues and live sites are marked with vo, stadiums are marked with vs, while the restaurants of the major sponsor, McDonalds, are annotated with vm. Last, the set of users visiting a place p are denoted by U(p) and the social network... venues to be a strong factor. Research investigating the interplay between social network ties and user movements has confirmed the influence of friends on the general human mobility (Back- strom, Sun, and Marlow 2010; Sadilek, Kautz, and Bigham 2012; Cho...

  16. A New Forecasting Model for USD/CNY Exchange Rate

    E-Print Network [OSTI]

    Cai, Zongwu; Chen, Linna; Fang, Ying

    2012-09-18

    hypothesis and using GARCH type models or their variants, most studies found evidence of nonlinearity in volatilities of exchange rates; see, for example, Bollerslev (1990), Brock, Hsieh and Lebaron (1991), Engle, Ito and Lin (1990), West and Cho (1995.... Alternatively, one might consider other smoothing variables used in the literature, such as the moving average technique trading rule (MATTR) Ut,MATTR = Yt?1 ?L j=1 Yt?j/L ? 1 for certain L (say, L = 21), as in Brock, Lakonishock and Lebaron (1992) and Hong...

  17. Scattering Properties of Oriented Hexagonal Ice Crystals

    E-Print Network [OSTI]

    Zhang, Feng

    2010-01-14

    )proposed by Bar- ber and Yeh [27]. Mischenko [15] further developed this method and wrote a solid code to be made available to the public. A very important feature of the T-matrix method is that the T-matrix itself does not depend on either the propagation direc... relation: CALIPSO lidar measurements vs. theory," Opt. Exp. 15, 5327 5332 (2007). [9] H.-M Cho, P. Yang, G. W. Kattawar, S. L. Nasiri, Y. Hu, P. Minnis, C. Tepte, and D. Winker, "Depolarization ratio and attenuated backscatter for nine cloud types: analyses...

  18. DOE/GO/15075-MacDiarmid-Wang Final Technical Report

    SciTech Connect (OSTI)

    Wang, Pen-Cheng

    2007-11-01

    Since Cho et al. reported up to ~8 wt% room-temperature hydrogen adsorption in HCl-treated polyaniline and polypyrrole [1], the research on the interactions between hydrogen and conducting polymers has become an area of special interest in the hydrogen economy community. However, later studies on hydrogen sorption using conducting polymers gave controversial results, which showed either much lower H2 uptake [2] or no H2 uptake at all [3]. As conducting polymers possess some unique unconventional and complex characteristics [4], it is highly likely that the controversial results could be attributed to the variation in material characteristics caused by ambiguous processing/handling procedures employed in H2 uptake studies involving conducting polymers. In order to determine whether conducting polymers can be developed into a new type of high-performance media for hydrogen storage applications, the goals of the project were to (i) confirm the brief report by Cho et al. [1] that ~8 wt% hydrogen gas storage in doped (metallic) forms of organic conducting polymers (synthetic metals), polyaniline and polypyrrole, can be attained, (ii) determine the optimum polymer preparative methods, chemical composition, polymer electrode potential, polymer crystallinity and morphology to give quantitative optimum conditions of hydrogen gas adsorption and desorption and (iii) investigate hydrogen storage by the many known types of organic conducting polymers in their semiconducting and, metallic forms, and in selected oxidation states.

  19. Correlation between human observer performance and model observer performance in differential phase contrast CT

    SciTech Connect (OSTI)

    Li, Ke; Garrett, John; Chen, Guang-Hong

    2013-11-15

    Purpose: With the recently expanding interest and developments in x-ray differential phase contrast CT (DPC-CT), the evaluation of its task-specific detection performance and comparison with the corresponding absorption CT under a given radiation dose constraint become increasingly important. Mathematical model observers are often used to quantify the performance of imaging systems, but their correlations with actual human observers need to be confirmed for each new imaging method. This work is an investigation of the effects of stochastic DPC-CT noise on the correlation of detection performance between model and human observers with signal-known-exactly (SKE) detection tasks.Methods: The detectabilities of different objects (five disks with different diameters and two breast lesion masses) embedded in an experimental DPC-CT noise background were assessed using both model and human observers. The detectability of the disk and lesion signals was then measured using five types of model observers including the prewhitening ideal observer, the nonprewhitening (NPW) observer, the nonprewhitening observer with eye filter and internal noise (NPWEi), the prewhitening observer with eye filter and internal noise (PWEi), and the channelized Hotelling observer (CHO). The same objects were also evaluated by four human observers using the two-alternative forced choice method. The results from the model observer experiment were quantitatively compared to the human observer results to assess the correlation between the two techniques.Results: The contrast-to-detail (CD) curve generated by the human observers for the disk-detection experiments shows that the required contrast to detect a disk is inversely proportional to the square root of the disk size. Based on the CD curves, the ideal and NPW observers tend to systematically overestimate the performance of the human observers. The NPWEi and PWEi observers did not predict human performance well either, as the slopes of their CD curves tended to be steeper. The CHO generated the best quantitative agreement with human observers with its CD curve overlapping with that of human observer. Statistical equivalence between CHO and humans can be claimed within 11% of the human observer results, including both the disk and lesion detection experiments.Conclusions: The model observer method can be used to accurately represent human observer performance with the stochastic DPC-CT noise for SKE tasks with sizes ranging from 8 to 128 pixels. The incorporation of the anatomical noise remains to be studied.

  20. Thermochemical Insight into the Reduction of CO to CH3OH with [Re(CO)]+ and [Mn(CO)]+ Complexes

    SciTech Connect (OSTI)

    Wiedner, Eric S.; Appel, Aaron M.

    2014-05-22

    To gain insight into thermodynamic barriers for reduction of CO into CH3OH, free energies for reduction of [CpRe(PPh3)(NO)(CO)]+ into CpRe(PPh3)(NO)(CH2OH) have been determined from experimental measurements. Using model complexes, the free energies for the transfer of H+, H, and e have been determined. A pKa of 10.6 was estimated for [CpRe(PPh3)(NO)(CHOH)]+ by measuring the pKa for the analogous [CpRe(PPh3)(NO)(CMeOH)]+. The hydride donor ability (?GH) of CpRe(PPh3)(NO)(CH2OH) was estimated to be 58.0 kcal mol1, based on calorimetry measurements of the hydride transfer reaction between CpRe(PPh3)(NO)(CHO) and [CpRe(PPh3)(NO)(CHOMe)]+ to generate the methylated analog, CpRe(PPh3)(NO)(CH2OMe). Cyclic voltammograms recorded on CpRe(PPh3)(NO)(CMeO), CpRe(PPh3)(NO)(CH2OMe), and [CpRe(PPh3)(NO)(CHOMe)]+ displayed either a quasireversible oxidation (neutral species) or reduction (cationic species). These potentials were used as estimates for the oxidation of CpRe(PPh3)(NO)(CHO) or CpRe(PPh3)(NO)(CH2OH), or the reduction of [CpRe(PPh3)(NO)(CHOH)]+. Combination of the thermodynamic data permits construction of three-dimensional free energy landscapes under varying conditions of pH and PH2. The free energy for H2 addition (?GH2) to [CpRe(PPh3)(NO)(CO)]+ (+15 kcal mol1) was identified as the most significant thermodynamic impediment for the reduction of CO. DFT computations indicate that ?GH2 varies by only 4.3 kcal mol1 across a series of [CpXRe(L)(NO)(CO)]+, while the experimental ?GH values for the analogous series of CpRe(PPh3)(NO)(CHO) varies by 12.9 kcal mol1. The small range of ?GH2 values is attributed to a minimal change in the CO bond polarization upon modification of the ancillary ligands, as determined from the computed atomic charges. This work was supported by the US Department of Energy, Office of Basic Energy Sciences, Division of Chemical Sciences, Geosciences & Biosciences. Pacific Northwest National Laboratory (PNNL) is a multiprogram national laboratory operated for DOE by Battelle.

  1. Tumor Metabolism and Perfusion in Head and Neck Squamous Cell Carcinoma: Pretreatment Multimodality Imaging With {sup 1}H Magnetic Resonance Spectroscopy, Dynamic Contrast-Enhanced MRI, and [{sup 18}F]FDG-PET

    SciTech Connect (OSTI)

    Jansen, Jacobus F.A.; Schoeder, Heiko; Lee, Nancy Y.; Stambuk, Hilda E.; Wang Ya; Fury, Matthew G.; Patel, Senehal G.; Pfister, David G.; Shah, Jatin P.; Koutcher, Jason A.; Shukla-Dave, Amita

    2012-01-01

    Purpose: To correlate proton magnetic resonance spectroscopy ({sup 1}H-MRS), dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), and {sup 18}F-labeled fluorodeoxyglucose positron emission tomography ([{sup 18}F]FDG PET) of nodal metastases in patients with head and neck squamous cell carcinoma (HNSCC) for assessment of tumor biology. Additionally, pretreatment multimodality imaging was evaluated for its efficacy in predicting short-term response to treatment. Methods and Materials: Metastatic neck nodes were imaged with {sup 1}H-MRS, DCE-MRI, and [{sup 18}F]FDG PET in 16 patients with newly diagnosed HNSCC, before treatment. Short-term patient radiological response was evaluated at 3 to 4 months. Correlations among {sup 1}H-MRS (choline concentration relative to water [Cho/W]), DCE-MRI (volume transfer constant [K{sup trans}]; volume fraction of the extravascular extracellular space [v{sub e}]; and redistribution rate constant [k{sub ep}]), and [{sup 18}F]FDG PET (standard uptake value [SUV] and total lesion glycolysis [TLG]) were calculated using nonparametric Spearman rank correlation. To predict short-term responses, logistic regression analysis was performed. Results: A significant positive correlation was found between Cho/W and TLG ({rho} = 0.599; p = 0.031). Cho/W correlated negatively with heterogeneity measures of standard deviation std(v{sub e}) ({rho} = -0.691; p = 0.004) and std(k{sub ep}) ({rho} = -0.704; p = 0.003). Maximum SUV (SUVmax) values correlated strongly with MRI tumor volume ({rho} = 0.643; p = 0.007). Logistic regression indicated that std(K{sup trans}) and SUVmean were significant predictors of short-term response (p < 0.07). Conclusion: Pretreatment multimodality imaging using {sup 1}H-MRS, DCE-MRI, and [{sup 18}F]FDG PET is feasible in HNSCC patients with nodal metastases. Additionally, combined DCE-MRI and [{sup 18}F]FDG PET parameters were predictive of short-term response to treatment.

  2. Studies directed towards the synthesis of (-)-Ebelactone-A

    E-Print Network [OSTI]

    Foster, Colin Frederick

    1999-01-01

    -anti arrangement required. As a vinylogous ?-dicarbonyl compound, ester 4 O O OHHO OMe O O O O OHO HO OH MeO O OMe HO OH OH MeO Swinholide A O O OMe NMe 2 OOH MeO OMe O OH O N CHO OAc O Me 2 N Aply ronine A Figure 2.1b 21 is significantly acidic, so... be in the homochiral series.) He then developed a simple and efficient synthesis of the optically active allenylsilane 62 (scheme 2.14). Me 3 Si SiMe 3 Me 3 Si O Me 3 Si OH Me 3 Si SO 2 CS 2 , 0C, 2.5 h AlCl 3 , CH 3 COCl 9-BBN dimer (S)-?-pinene r.t., ov...

  3. Synthesis and crystal structure of ?,?-unsaturated ketone: 3,3?-[1,2-ethanediylbis(oxy-2,1-phenylene)]bis[1-(2-pyridyl) -2-propen-1-one

    SciTech Connect (OSTI)

    Wang, G.-F. Gong, Q.-J. Sun, H.; Yao, C-Z.

    2013-12-15

    The title compound, C{sub 30}H{sub 24}N{sub 2}O{sub 4}, 3,3?-[1,2-ethanediyl-bis(oxy-2,1-phenylene)]bis[1-(2-pyridyl) -2-propen-1-one] was synthesized and characterized by elemental analysis, FT-IR spectra, {sup 1}H NMR, and X-ray single-crystal diffraction. In the molecule, the pyridine plane and the adjacent phenyl plane are almost coplanar with the dihedral angle of 3.07, while the dihedral angle between the mean planes of the two asymmetric units is 67.56. The crystal packing is stabilized by weak intermolecular C-H...N and C-H...O hydrogen bonds, C-H...? and ?...? stacking interactions.

  4. Crystal structure of 4-[benzylideneamino]-3-thiophen-2-yl-methyl-4,5-dihydro-1H-[1,2,4] triazole-5-one

    SciTech Connect (OSTI)

    Tanak, H.

    2013-12-15

    The crystal structure of the title compound C{sub 14}H{sub 12}N{sub 4}OS was determined by the X-ray diffraction method. The compound crystallizes in the triclinic space group P-bar1with Z = 2. The molecule is not planar: the dihedral angle between the triazole and thiophene rings is 73.98(2), and that between the triazole and benzene rings is 4.05(2). The thiophene ring is disordered over two positions, which are approximately parallel and oppositely oriented. The major component refined to a site-occupancy factor of 0.573(3). An intramolecular C-H...O hydrogen bond generates an S(6) ring motif. In the crystal, molecules are linked together by two pairs of N-H...O interactions (to the same O atom as acceptor), forming inversion dimers. The crystal packing is also stabilized by ?-? interactions [centroid-centroid distance is 3.978 ].

  5. Measurement of the ?(0)(b) Lifetime Using Semileptonic Decays

    E-Print Network [OSTI]

    Baringer, Philip S.; Bean, Alice; Hensel, Carsten; Moulik, Tania; Wilson, Graham Wallace; Abazov, V. M.; Abbott, B.; Abolins, M.; Acharya, B. S.; Adams, M.

    2007-10-30

    . Chan,5 A. Chandra,48 F. Charles,18 E. Cheu,45 F. Chevallier,13 D.K. Cho,62 S. Choi,31 B. Choudhary,27 L. Christofek,77 T. Christoudias,43 S. Cihangir,50 D. Claes,67 C. Clement,40 B. Clement,18 Y. Coadou,5 M. Cooke,80 W. E. Cooper,50 M. Corcoran,80 F.... The expected number of signal events in each bin, nei , is given by nei #6; Ntot R i f#4; M#5;d M, where Ntot is the total number of #1;#1;#2;c events, and f#4; M#5; is the probability density function (PDF) for M. The integration is done within the range of a...

  6. Layer-by-Layer Assembly of Enzymes on Carbon Nanotubes

    SciTech Connect (OSTI)

    Wang, Jun; Liu, Guodong; Lin, Yuehe

    2008-06-01

    The use of Layer-by-layer techniques for immobilizing several types of enzymes, e.g. glucose oxidase (GOx), horse radish oxidases(HRP), and choline oxidase(CHO) on carbon nanotubes and their applications for biosenseing are presented. The enzyme is immobilized on the negatively charged CNT surface by alternatively assembling a cationic polydiallyldimethyl-ammonium chloride (PDDA) layer and a enzyme layer. The sandwich-like layer structure (PDDA/enzyme/PDDA/CNT) formed by electrostatic assembling provides a favorable microenvironment to keep the bioactivity of enzyme and to prevent enzyme molecule leakage. The morphologies and electrocatalytic acitivity of the resulted enzyme film were characterized using TEM and electrochemical techniques, respectively. It was found that these enzyme-based biosensors are very sensitive, selective for detection of biomolecules, e.g. glucose, choline.

  7. Crystal structure of 1-methyl-3-([2,2-dimethyl-4,6-dioxo-1,3-dioxane-5-ylidene]methyl)urea

    SciTech Connect (OSTI)

    Habibi, A. Ghorbani, H. S.; Bruno, G.; Rudbari, H. A.; Valizadeh, Y.

    2013-12-15

    The crystal structure of 1-Methyl-3-([2,2-dimethyl-4,6-dioxo-1,3-dioxane-5-ylidene]methyl)urea (C{sub 9}H{sub 12}N{sub 2}O{sub 5}) has been determined by single crystal X-ray diffraction analysis. The crystals are monoclinic, a = 5.3179(2), b = 18.6394(6), c =10.8124(3) , ? = 100.015(2), Z = 4, sp. gr. P2{sub 1}/c, R = 0.0381 for 2537 reflections with I > 2?(I). Except for C(CH{sub 3}){sub 2} group, the molecule is planar. The structure is stabilized by inter- and intramolecular N-H...O hydrogen bonds and weak C-H...O interactions.

  8. Retrofit Projects Through Pinch Technology

    E-Print Network [OSTI]

    Linnhoff, B.; Vredeveld, D. R.

    1984-01-01

    Ital cost targets as a funct10n of 6T m l n sImIlar to th energy targets. Energy and capItal targets comb1ned should enable the engIneer to make better InItIal judgements about the correct economIc choIce for 6T m ln' 344 ESL-IE-84-04-64 Proceedings... to des1gn net rks whIch approxImate the pred1cted opt1mu trade-off between cap1tal and energy costs. the eng1neer w111 flnd 1t helpful to cons1der a d1agram such as f1gure 4a. The temperature d1fference t>T between hot compos1te and cold compos...

  9. Lipocalin 2 regulation by thermal stresses: Protective role of Lcn2/NGAL against cold and heat stresses

    SciTech Connect (OSTI)

    Roudkenar, Mehryar Habibi, E-mail: roudkenar@ibto.ir [Research Center, Iranian Blood Transfusion Organization, Tehran (Iran, Islamic Republic of); Halabian, Raheleh [Research Center, Iranian Blood Transfusion Organization, Tehran (Iran, Islamic Republic of)] [Research Center, Iranian Blood Transfusion Organization, Tehran (Iran, Islamic Republic of); Roushandeh, Amaneh Mohammadi [Department of Anatomy, Faculty of Medicine, Medical University of Tabriz, Tabriz (Iran, Islamic Republic of)] [Department of Anatomy, Faculty of Medicine, Medical University of Tabriz, Tabriz (Iran, Islamic Republic of); Nourani, Mohammad Reza [Chemical Injury Research Center, Baqiyatallah Medical Science University, Tehran (Iran, Islamic Republic of)] [Chemical Injury Research Center, Baqiyatallah Medical Science University, Tehran (Iran, Islamic Republic of); Masroori, Nasser [Research Center, Iranian Blood Transfusion Organization, Tehran (Iran, Islamic Republic of)] [Research Center, Iranian Blood Transfusion Organization, Tehran (Iran, Islamic Republic of); Ebrahimi, Majid [Research Center, Iranian Blood Transfusion Organization, Tehran (Iran, Islamic Republic of) [Research Center, Iranian Blood Transfusion Organization, Tehran (Iran, Islamic Republic of); Chemical Injury Research Center, Baqiyatallah Medical Science University, Tehran (Iran, Islamic Republic of); Nikogoftar, Mahin; Rouhbakhsh, Mehdi; Bahmani, Parisa [Research Center, Iranian Blood Transfusion Organization, Tehran (Iran, Islamic Republic of)] [Research Center, Iranian Blood Transfusion Organization, Tehran (Iran, Islamic Republic of); Najafabadi, Ali Jahanian [Department of Molecular Biology, Pasteur Institute of Iran, Tehran (Iran, Islamic Republic of)] [Department of Molecular Biology, Pasteur Institute of Iran, Tehran (Iran, Islamic Republic of); Shokrgozar, Mohammad Ali [National Cell Bank of Iran, Pasteur institute of Iran, Tehran (Iran, Islamic Republic of)] [National Cell Bank of Iran, Pasteur institute of Iran, Tehran (Iran, Islamic Republic of)

    2009-11-01

    Environmental temperature variations are the most common stresses experienced by a wide range of organisms. Lipocalin 2 (Lcn2/NGAL) is expressed in various normal and pathologic conditions. However, its precise functions have not been fully determined. Here we report the induction of Lcn2 by thermal stresses in vivo, and its role following exposure to cold and heat stresses in vitro. Induction of Lcn2 in liver, heart and kidney was detected by RT-PCR, Western blot and immunohistochemistry following exposure of mice to heat and cold stresses. When CHO and HEK293T cells overexpressing NGAL were exposed to cold stress, cell proliferation was higher compared to controls. Down-regulatrion of NGAL by siRNA in A549 cells resulted in less proliferation when exposed to cold stress compared to control cells. The number of apoptotic cells and expression of pro-apoptotic proteins were lower in the NGAL overexpressing CHO and HEK293T cells, but were higher in the siRNA-transfected A549 cells compared to controls, indicating that NGAL protects cells against cold stress. Following exposure of the cells to heat stress, ectopic expression of NGAL protected cells while addition of exogenous recombinant NGAL to the cell culture medium exacerbated the toxicity of heat stress specially when there was low or no endogenous expression of NGAL. It had a dual effect on apoptosis following heat stress. NGAL also increased the expression of HO-1. Lcn2/NGAL may have the potential to improve cell proliferation and preservation particularly to prevent cold ischemia injury of transplanted organs or for treatment of some cancers by hyperthermia.

  10. Histamine acting on H1 receptor promotes inhibition of proliferation via PLC, RAC, and JNK-dependent pathways

    SciTech Connect (OSTI)

    Notcovich, Cintia; Laboratorio de Farmacologia de Receptores, Catedra de Quimica Medicinal, Departamento de Farmacologia, Facultad de Farmacia y Bioquimica, Universidad de Buenos Aires ; Diez, Federico; Tubio, Maria Rosario; Laboratorio de Farmacologia de Receptores, Catedra de Quimica Medicinal, Departamento de Farmacologia, Facultad de Farmacia y Bioquimica, Universidad de Buenos Aires ; Baldi, Alberto; Consejo Nacional de Investigaciones Cientificas y Tecnicas, Buenos Aires ; Kazanietz, Marcelo G.; Davio, Carlos; Consejo Nacional de Investigaciones Cientificas y Tecnicas, Buenos Aires ; Shayo, Carina; Consejo Nacional de Investigaciones Cientificas y Tecnicas, Buenos Aires

    2010-02-01

    It is well established that histamine modulates cell proliferation through the activation of the histamine H1 receptor (H1R), a G protein-coupled receptor (GPCR) that is known to couple to phospholipase C (PLC) activation via Gq. In the present study, we aimed to determine whether H1R activation modulates Rho GTPases, well-known effectors of Gq/G{sub 11}-coupled receptors, and whether such modulation influences cell proliferation. Experiments were carried out in CHO cells stably expressing H1R (CHO-H1R). By using pull-down assays, we found that both histamine and a selective H1R agonist activated Rac and RhoA in a time- and dose-dependent manner without significant changes in the activation of Cdc42. Histamine response was abolished by the H1R antagonist mepyramine, RGS2 and the PLC inhibitor U73122, suggesting that Rac and RhoA activation is mediated by H1R via Gq coupling to PLC stimulation. Histamine caused a marked activation of serum response factor activity via the H1R, as determined with a serum-responsive element (SRE) luciferase reporter, and this response was inhibited by RhoA inactivation with C3 toxin. Histamine also caused a significant activation of JNK which was inhibited by expression of the Rac-GAP {beta}2-chimaerin. On the other hand, H1R-induced ERK1/2 activation was inhibited by U73122 but not affected by C3 or {beta}2-chimaerin, suggesting that ERK1/2 activation was dependent on PLC and independent of RhoA or Rac. [{sup 3}H]-Thymidine incorporation assays showed that both histamine and the H1R agonist inhibited cell proliferation in a dose-dependent manner and that the effect was independent of RhoA but partially dependent on JNK and Rac. Our results reveal that functional coupling of the H1R to Gq-PLC leads to the activation of RhoA and Rac small GTPases and suggest distinct roles for Rho GTPases in the control of cell proliferation by histamine.

  11. Prominin-2 expression increases protrusions, decreases caveolae and inhibits Cdc42 dependent fluid phase endocytosis

    SciTech Connect (OSTI)

    Singh, Raman Deep Schroeder, Andreas S.; Scheffer, Luana; Holicky, Eileen L.; Wheatley, Christine L.; Marks, David L. Pagano, Richard E.

    2013-05-10

    Highlights: Prominin-2 expression induced protrusions that co-localized with lipid raft markers. Prominin-2 expression decreased caveolae, caveolar endocytosis and increased pCav1. Prominin-2 expression inhibited fluid phase endocytosis by inactivation of Cdc42. These endocytic effects can be reversed by adding exogenous cholesterol. Caveolin1 knockdown restored fluid phase endocytosis in Prominin2 expressing cells. -- Abstract: Background: Membrane protrusions play important roles in biological processes such as cell adhesion, wound healing, migration, and sensing of the external environment. Cell protrusions are a subtype of membrane microdomains composed of cholesterol and sphingolipids, and can be disrupted by cholesterol depletion. Prominins are pentaspan membrane proteins that bind cholesterol and localize to plasma membrane (PM) protrusions. Prominin-1 is of great interest as a marker for stem and cancer cells, while Prominin-2 (Prom2) is reportedly restricted to epithelial cells. Aim: To characterize the effects of Prom-2 expression on PM microdomain organization. Methods: Prom2-fluorescent protein was transfected in human skin fibroblasts (HSF) and Chinese hamster ovary (CHO) cells for PM raft and endocytic studies. Caveolae at PM were visualized using transmission electron microscopy. Cdc42 activation was measured and caveolin-1 knockdown was performed using siRNAs. Results: Prom2 expression in HSF and CHO cells caused extensive Prom2-positive protrusions that co-localized with lipid raft markers. Prom2 expression significantly decreased caveolae at the PM, reduced caveolar endocytosis and increased caveolin-1 phosphorylation. Prom2 expression also inhibited Cdc42-dependent fluid phase endocytosis via decreased Cdc42 activation. Effects on endocytosis were reversed by addition of cholesterol. Knockdown of caveolin-1 by siRNA restored Cdc42 dependent fluid phase endocytosis in Prom2-expressing cells. Conclusions: Prom2 protrusions primarily localize to lipid rafts and recruit cholesterol into protrusions and away from caveolae, leading to increased phosphorylation of caveolin-1, which inhibits Cdc42-dependent endocytosis. This study provides a new insight for the role for prominins in the regulation of PM lipid organization.

  12. Final Technical Report "Catalytic Hydrogenation of Carbon Monoxide and Olefin Oxidation" Grant number : DE-FG02-86ER13615

    SciTech Connect (OSTI)

    Wayland, B.B.

    2009-08-31

    Title: Catalytic Hydrogenation of Carbon Monoxide and Olefin Oxidation Grant No. DE-FG02-86ER13615 PI: Wayland, B. B. (wayland@sas.upenn.edu) Abstract Development of new mechanistic strategies and catalyst materials for activation of CO, H2, CH4, C2H4, O2, and related substrates relevant to the conversion of carbon monoxide, alkanes, and alkenes to organic oxygenates are central objectives encompassed by this program. Design and synthesis of metal complexes that manifest reactivity patterns associated with potential pathways for the hydrogenation of carbon monoxide through metallo-formyl (M-CHO), dimetal ketone (M-C(O)-M), and dimetal dionyl (M-C(O)-C(O)-M) species is one major focus. Hydrocarbon oxidation using molecular oxygen is a central goal for methane activation and functionalization as well as regioselective oxidation of olefins. Discovery of new reactivity patterns and control of selectivity are pursued through designing new metal complexes and adjusting reaction conditions. Variation of reaction media promotes distinct reaction pathways that control both reaction rates and selectivities. Dimetalloradical diporphyrin complexes preorganize transition states for substrate reactions that involve two metal centers and manifest large rate increases over mono-metalloradical reactions of hydrogen, methane, and other small molecule substrates. Another broad goal and recurring theme of this program is to contribute to the thermodynamic database for a wide scope of organo-metal transformations in a range of reaction media. One of the most complete descriptions of equilibrium thermodynamics for organometallic reactions in water and methanol is emerging from the study of rhodium porphyrin substrate reactions in aqueous and alcoholic media. Water soluble group nine metalloporphyrins manifest remarkably versatile substrate reactivity in aqueous and alcoholic media which includes producing rhodium formyl (Rh-CHO) and hydroxy methyl (Rh-CH2OH) species. Exploratory directions for this program include expending new strategies for anti-Markovnikov addition of water, alcohols, and amines with olefins, developing catalytic reactions of CO to give formamides and formic esters, and evaluating the potential for coupling reactions of CO to produce organic building blocks.

  13. Enhancement of Kv1.3 Potassium Conductance by Extremely Low Frequency Electromagnetic Field

    E-Print Network [OSTI]

    Cecchetto, Claudia; Boccaccio, Pasquale; Vassanelli, Stefano

    2015-01-01

    Theoretical and experimental evidences support the hypothesis that extremely low-frequency electromagnetic fields can affect voltage-gated channels. Little is known, however, about their effect on potassium channels. Kv1.3, a member of the voltage-gated potassium channels family originally discovered in the brain, is a key player in important biological processes including antigen-dependent activation of T-cells during the immune response. We report that Kv1.3 expressed in CHO-K1 cells can be modulated in cell subpopulations by extremely low frequency and relatively low intensity electromagnetic fields. In particular, we observed that field exposure can cause an enhancement of Kv1.3 potassium conductance and that the effect lasts for several minutes after field removal. The results contribute to put immune and nervous system responses to extremely low-frequency electromagnetic fields into a new perspective, with Kv1.3 playing a pivotal molecular role. Keywords: immunotherapy, immunomodulation, potassium chann...

  14. Enhancement of Kv1.3 Potassium Conductance by Extremely Low Frequency Electromagnetic Field

    E-Print Network [OSTI]

    Claudia Cecchetto; Marta Maschietto; Pasquale Boccaccio; Stefano Vassanelli

    2015-08-25

    Theoretical and experimental evidences support the hypothesis that extremely low-frequency electromagnetic fields can affect voltage-gated channels. Little is known, however, about their effect on potassium channels. Kv1.3, a member of the voltage-gated potassium channels family originally discovered in the brain, is a key player in important biological processes including antigen-dependent activation of T-cells during the immune response. We report that Kv1.3 expressed in CHO-K1 cells can be modulated in cell subpopulations by extremely low frequency and relatively low intensity electromagnetic fields. In particular, we observed that field exposure can cause an enhancement of Kv1.3 potassium conductance and that the effect lasts for several minutes after field removal. The results contribute to put immune and nervous system responses to extremely low-frequency electromagnetic fields into a new perspective, with Kv1.3 playing a pivotal molecular role. Keywords: immunotherapy, immunomodulation, potassium channels, gating, electromagnetic fields

  15. High-order harmonic generation at a repetition rate of 100 kHz

    E-Print Network [OSTI]

    Lindner, F.; Stremme, W.; Schatzel, M. G.; Grasbon, F.; Paulus, Gerhard G.; Walther, H.; Hartmann, R.; Struder, L.

    2003-01-01

    . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 6 SUMMARY Kerne l s o f 169 conver ted e x o t i c l i n e s o f sorghum, Sorghum b i c o l o r (L.) Moench, were sc reened f o r r e s i s t a n c e t o t h e maize weev i l , S i t o p h i l u s zeamais Motsch., u t i l i z i n... g f ree -cho ice and no-choice s c r e e n i n g tech- n iques . The c r i t e r i a used f o r i n i t i a l e v a l u a t i o n of samples o f each l i n e were a t t r a c t i v e n e s s t o maize weev i l a d u l t s and t h e...

  16. Complexation of n SO{sub 2} molecules (n = 1, 2, 3) with formaldehyde and thioformaldehyde

    SciTech Connect (OSTI)

    Azofra, Luis Miguel [Instituto de Qumica Mdica, CSIC, Juan de la Cierva, 3, E-28006, Madrid (Spain) [Instituto de Qumica Mdica, CSIC, Juan de la Cierva, 3, E-28006, Madrid (Spain); Department of Chemistry and Biochemistry, Utah State University, Logan, Utah 84322-0300 (United States); Scheiner, Steve, E-mail: steve.scheiner@usu.edu [Department of Chemistry and Biochemistry, Utah State University, Logan, Utah 84322-0300 (United States)] [Department of Chemistry and Biochemistry, Utah State University, Logan, Utah 84322-0300 (United States)

    2014-01-21

    Ab initio and density functional theory calculations are used to examine complexes formed between H{sub 2}CO and H{sub 2}CS with 1, 2, and 3 molecules of SO{sub 2}. The nature of the interactions is probed by a variety of means, including electrostatic potentials, natural bond orbital, atoms in molecules, energy decomposition, and electron density redistribution maps. The dimers are relatively strongly bound, with interaction energies exceeding 5 kcal/mol. The structures are cyclic, containing both a O/S?S chalcogen bond and a CH?O H-bond. Addition of a second SO{sub 2} molecule leads to a variety of heterotrimer structures, most of which resemble the original dimer, where the second SO{sub 2} molecule engages in a chalcogen bond with the first SO{sub 2}, and a C?O attraction with the H{sub 2}CX. Some cooperativity is apparent in the trimers and tetramers, with an attractive three-body interaction energy and shortened intermolecular distances.

  17. GAS-PHASE REACTIONS OF HYDRIDE ANION, H{sup -}

    SciTech Connect (OSTI)

    Martinez, Oscar; Yang Zhibo; Demarais, Nicholas J.; Bierbaum, Veronica M. [Department of Chemistry and Biochemistry, 215 UCB, University of Colorado, Boulder, CO 80309-0215 (United States); Snow, Theodore P., E-mail: Oscar.Martinez@colorado.ed, E-mail: Zhibo.Yang@colorado.ed, E-mail: Nicholas.Demarais@colorado.ed, E-mail: Veronica.Bierbaum@colorado.ed, E-mail: Theodore.Snow@colorado.ed [Department of Astrophysical and Planetary Sciences, 391 UCB, University of Colorado, Boulder, CO 80309-0391 (United States)

    2010-09-01

    Rate constants were measured at 300 K for the reactions of the hydride anion, H{sup -}, with neutral molecules C{sub 2}H{sub 2}, H{sub 2}O, CH{sub 3}CN, CH{sub 3}OH, (CH{sub 3}){sub 2}CO, CH{sub 3}CHO, N{sub 2}O, CO{sub 2}, O{sub 2}, CO, CH{sub 3}Cl, (CH{sub 3}){sub 3}CCl, (CH{sub 3}CH{sub 2}){sub 2}O, C{sub 6}H{sub 6}, and D{sub 2} using a flowing-afterglow instrument. Experimental work was supplemented by ab initio calculations to provide insight into the viability of reaction pathways. Our reported rate constants should prove useful to models of astrophysical environments where conditions prevail for the existence of both H{sup -} and neutral species. The variety of neutral reactants studied includes representative species from prototypical chemical groups, effectively mapping reactivity trends for the hydride anion.

  18. Stress-induced nuclear export of 5-lipoxygenase

    SciTech Connect (OSTI)

    Hanaka, Hiromi [Department of Molecular Biochemistry, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511 (Japan); Shimizu, Takao [Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan); Izumi, Takashi [Department of Molecular Biochemistry, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511 (Japan)]. E-mail: takizumi@med.gunma-u.ac.jp

    2005-12-09

    A key enzyme for leukotriene biosynthesis is 5-lipoxygenase (5-LO), which we found is exported from the nucleus when p38 MAPK is activated. CHO-K1 cells stably express green fluorescent protein-5-lipoxygenase fusion protein (GFP-5LO), which is located predominantly in the nucleus, and is exported by anisomycin, hydrogen peroxide, and sorbitol, with activation of p38 MAPK. SB203580, an inhibitor of p38 MAPK, and Leptomycin B, an inhibitor of the nuclear export, blocked the anisomycin-induced export of GFP-5LO. When HEK293 cells were transformed with plasmids for wild-type GFP-5LO, GFP-5LO-S271A or GFP-5LO-S271E mutants, most wild-type GFP-5LO and GFP-5LO-S271A localized in the nucleus, but GFP-5LO-S271E localized in the cytosol. Thus, phosphorylation at Ser-271 of 5-LO is important for its export. Endogenous 5-LO in RBL cells stimulated with anisomycin was also exported from the nucleus. These results suggest that the nuclear export of 5-LO depends on the stress-induced activation of the p38 MAPK pathway.

  19. Modeling of the formation of short-chain acids in propane flames

    E-Print Network [OSTI]

    Battin-Leclerc, Frdrique; Jaffrezo, J L; Legrand, M

    2009-01-01

    In order to better understand their potential formation in combustion systems, a detailed kinetic mechanism for the formation of short-chain monocarboxylic acids, formic (HCOOH), acetic (CH3COOH), propionic (C2H5COOH) and propenic (C2H3COOH)) acids, has been developed. Simulations of lean (equivalence ratios from 0.9 to 0.48) laminar premixed flames of propane stabilized at atmospheric pressure with nitrogen as diluent have been performed. It was found that amounts up to 25 ppm of acetic acid, 15 ppm of formic acid and 1 ppm of C3 acid can be formed for some positions in the flames. Simulations showed that the more abundant C3 acid formed is propenic acid. A quite acceptable agreement has been obtained with the scarce results from the literature concerning oxygenated compounds, including aldehydes (CH2O, CH3CHO) and acids. A reaction pathways analysis demonstrated that each acid is mainly derived from the aldehyde of similar structure.

  20. Comparative Density Functional Study of Methanol Decomposition on Cu4 and Co4 Clusters

    SciTech Connect (OSTI)

    Mehmood, Faisal; Greeley, Jeffrey P.; Zapol, Peter; Curtiss, Larry A.

    2010-11-18

    A density functional theory study of the decomposition of methanol on Cu4 and Co4 clusters is presented. The reaction intermediates and activation barriers have been determined for reaction steps to form H2 and CO. For both clusters, methanol decomposition initiated by C-H and O-H bond breaking was investigated. In the case of a Cu4 cluster, methanol dehydrogenation through hydroxymethyl (CH2OH), hydroxymethylene (CHOH), formyl (CHO), and carbon monoxide (CO) is found to be slightly more favorable. For a Co4 cluster, the dehydrogenation pathway through methoxy (CH3O) and formaldehyde (CH2O) is slightly more favorable. Each of these pathways results in formation of CO and H2. The Co cluster pathway is very favorable thermodynamically and kinetically for dehydrogenation. However, since CO binds strongly, it is likely to poison methanol decomposition to H2 and CO at low temperatures. In contrast, for the Cu cluster, CO poisoning is not likely to be a problem since it does not bind strongly, but the dehydrogenation steps are not energetically favorable. Pathways involving C-O bond cleavage are even less energetically favorable. The results are compared to our previous study of methanol decomposition on Pd4 and Pd8 clusters. Finally, all reaction energy changes and transition state energies, including those for the Pd clusters, are related in a linear, Broensted-Evans-Polanyi plot.

  1. Resolving the chemical substructure of Orion-KL

    E-Print Network [OSTI]

    Feng, S; Henning, T; Semenov, D; Palau, Aina; Mills, E A C

    2015-01-01

    The Kleinmann-Low nebula in Orion (Orion-KL) is the nearest example of a high-mass star-forming environment. For the first time, we complemented 1.3 mm Submillimeter Array (SMA) interferometric line survey with IRAM 30 m single-dish observations of the Orion-KL region. Covering a 4 GHz bandwidth in total, this survey contains over 160 emission lines from 20 species (25 isotopologues), including 10 complex organic molecules (COMs). At a spatial resolution of 1200 AU, the continuum substructures are resolved. Extracting the spectra from individual substructures and providing the intensity-integrated distribution map for each species, we studied the small-scale chemical variations in this region. Our main results are: (1) We identify lines from the low-abundance COMs CH3COCH3 and CH3CH2OH, as well as tentatively detect CH3CHO and long carbon-chains C6H and HC7N. (2) We find that while most COMs are segregated by type, peaking either towards the hot core (e.g., N-bearing species) or the compact ridge (e.g., O-bea...

  2. Validity of the Effective Fisher matrix for parameter estimation analysis: Comparing to the analytic Fisher matrix

    E-Print Network [OSTI]

    Hee-Suk Cho; Chang-Hwan Lee

    2013-10-11

    The effective Fisher matrix method recently introduced by Cho et al. is a semi-analytic approach to the Fisher matrix, in which a local overlap surface is fitted by using a quadratic fitting function. Mathematically, the effective Fisher matrix should be consistent with the analytic one at the infinitesimal fitting scale. In this work, using the frequency-domain waveform (TaylorF2), we give brief comparison results between the effective and analytic Fisher matrices for several non-spinning binaries consisting of binary neutron stars with masses of (1.4, 1.4)M_sun, black hole-neutron star of (1.4, 10)M_sun, and binary black holes of (5, 5) and (10, 10)M_sun for a fixed signal to noise ratio (SNR=20) and show a good consistency between two methods. We also give a comparison result for an aligned-spin black hole-neutron star binary with a black hole spin of \\chi=1, where we define new mass parameters (Mc, \\eta^-1, \\chi^7/2) to find good fitting functions to the overlap surface. The effective Fisher matrix can also be computed by using the time-domain waveforms which are generally more accurate than frequency-domain waveform. We show comparison results between the frequency-domain and time-domain waveforms (TaylorT4) for both the non-spinning aligned-spin binaries.

  3. The one and a half monopoles solution of the SU(2) YangMillsHiggs field theory

    SciTech Connect (OSTI)

    Teh, Rosy Ng, Ban-Loong; Wong, Khai-Ming

    2014-04-15

    Recently we have reported on the existence of finite energy SU(2) YangMillsHiggs particle of one-half topological charge. In this paper, we show that this one-half monopole can co-exist with a t HooftPolyakov monopole. The magnetic charge of the one-half monopole is of opposite sign to the magnetic charge of the t HooftPolyakov monopole. However the net magnetic charge of the configuration is zero due to the presence of a semi-infinite Dirac string along the positive z-axis that carries the other half of the magnetic monopole charge. The solution possesses gauge potentials that are singular along the z-axis, elsewhere they are regular. The total energy is found to increase with the strength of the Higgs field self-coupling constant ?. However the dipole separation and the magnetic dipole moment decrease with ?. This solution is non-BPS even in the BPS limit when the Higgs self-coupling constant vanishes. -- Highlights: This one-half monopole can co-exist with a t HooftPolyakov monopole. The magnetic charge of the one-half monopole and one monopole is of opposite sign. This solution is non-BPS. The net magnetic charge of the configuration is zero. This solution upon Cho decomposition is only singular along the negative z-axis.

  4. Crystallization and X-ray structure of full-length recombinant human butyrylcholinesterase

    SciTech Connect (OSTI)

    Ngamelue, Michelle N.; Homma, Kohei [Pathology and Microbiology Department, University of Nebraska Medical Center, 986495 Nebraska Medical Center, Omaha, NE 68198-6495 (United States); Lockridge, Oksana [Eppley Cancer Institute, University of Nebraska Medical Center, 986805 Nebraska Medical Center, Omaha, NE 68198-6805 (United States); Asojo, Oluwatoyin A., E-mail: oasojo@unmc.edu [Pathology and Microbiology Department, University of Nebraska Medical Center, 986495 Nebraska Medical Center, Omaha, NE 68198-6495 (United States)

    2007-09-01

    The first crystals and the 2.8 X-ray structure of full-length recombinant human butyrylcholinesterase are reported. Human butyrylcholinesterase (BChE) has been shown to function as an endogenous scavenger of diverse poisons. BChE is a 340 kDa tetrameric glycoprotein that is present in human serum at a concentration of 5 mg l{sup ?1}. The well documented therapeutic effects of BChE on cocaine toxicity and organophosphorus agent poisoning has increased the need for effective methods of producing recombinant therapeutic BChE. In order to be therapeutically useful, BChE must have a long circulatory residence time or associate as tetramers. Full-length recombinant BChE produced in Chinese hamster ovary (CHO) cells or human embryonic kidney cells has been shown to associate as monomers, with a shorter circulatory residence time than the naturally occurring tetrameric serum protein. Based on the preceding observation as well as the need to develop novel methodologies to facilitate the mass production of therapeutic recombinant BChE, studies have been initiated to determine the structural basis of tetramer formation. Towards these ends, full-length monomeric recombinant BChE has been crystallized for the first time. A 2.8 X-ray structure was solved in space group P42{sub 1}2, with unit-cell parameters a = b = 156, c = 146 .

  5. Herschel observations of EXtra-Ordinary Sources: Analysis of the HIFI 1.2 THz Wide Spectral Survey Toward Orion KL II. Chemical Implications

    E-Print Network [OSTI]

    Crockett, Nathan R; Neill, Justin L; Favre, Ccile; Blake, Geoffrey A; Herbst, Eric; Anderson, Dana E; Hassel, George E

    2015-01-01

    We present chemical implications arising from spectral models fit to the Herschel/HIFI spectral survey toward the Orion Kleinmann-Low nebula (Orion KL). We focus our discussion on the eight complex organics detected within the HIFI survey utilizing a novel technique to identify those molecules emitting in the hottest gas. In particular, we find the complex nitrogen bearing species CH$_{3}$CN, C$_{2}$H$_{3}$CN, C$_{2}$H$_{5}$CN, and NH$_{2}$CHO systematically trace hotter gas than the oxygen bearing organics CH$_{3}$OH, C$_{2}$H$_{5}$OH, CH$_{3}$OCH$_{3}$, and CH$_{3}$OCHO, which do not contain nitrogen. If these complex species form predominantly on grain surfaces, this may indicate N-bearing organics are more difficult to remove from grain surfaces than O-bearing species. Another possibility is that hot (T$_{\\rm kin}$$\\sim$300 K) gas phase chemistry naturally produces higher complex cyanide abundances while suppressing the formation of O-bearing complex organics. We compare our derived rotation temperatures ...

  6. Crosslinked Polyamide

    DOE Patents [OSTI]

    Huang, Zhi H. (East Lansing, MI); McDonald, William F. (Utica, OH); Wright, Stacy C. (Lansing, MI); Taylor, Andrew C. (Ann Arbor, MI)

    2002-06-04

    A crosslinked polyamide material and a process for preparing the crosslinked polyamide material are disclosed. The crosslinked polyamide material comprises a crosslinked chemical combination of (1) a polyamide of the formula: ##STR1## wherein n is between about 50 and 10,000, wherein each R is between 1 and 50 carbon atoms alone and is optionally substituted with heteroatoms, oxygen, nitrogen, sulfur, or phosphorus and combinations thereof, wherein multiple of the R are in vertically aligned spaced relationship along a backbone forming the polyamide, and wherein two or more of the R contain an amino group; and (2) a crosslinking agent containing at least two functional groups capable of reacting with the amino groups of the polyamide. In one embodiment of the invention, the crosslinking agent is an aliphatic or aromatic isocyanate compound having 2 or more --N.dbd.C.dbd.O groups. In another embodiment of the invention, the crosslinking agent is an aliphatic aldehyde or aromatic aldehyde compound having 2 or more --CHO groups. In still another embodiment of the invention, the crosslinking agent is selected from a phosphine having the general formula (A).sub.2 P(B) and mixtures thereof, wherein A is hydroxyalkyl, and B is hydroxyalkyl, alkyl, or aryl. In yet another embodiment of the invention, the crosslinking agent is selected from the group consisting of epoxy resins having more than one epoxide group per molecule.

  7. Recent developments with the human repair genes ERCC2, ERCC4, and XRCC1

    SciTech Connect (OSTI)

    Thompson, L.H.; Caldecott, K.W.; Brookman, K.W.; Weber, C.A.; Salazar, E.S.; Takayama, K.; Fornace, A.J.

    1992-11-06

    ERCC2 was first identified as a gene on human chromosome 19 that complemented the UV sensitivity of CHO UV5 cells in somatic cell hybrids. Subsequent studies localized ERCC2 to the same chromosomal region (19q13.2--13.3) as the ERCC1 gene and showed that the two genes were less than 250 kb apart. Cloning of ERCC2 was accomplished by transfection of genomic DNA into UV5 cells and rescue of the gene from a secondary transformant. Recovery of the gene was aided by the presence of repetitive sequences that were detected on Southern blots with a probe for Alu-family repeats. ERCC2, which is 19 kb in size, quantitatively corrected the UV sensitivity and incision defect in UV5 cells upon transfection. An ERCC2 CDNA clone was recovered from the pcD2 expression library. Although this clone was truncated at the 5 in. end, it conferred transient, but not stable, correction to UV5 cells upon transfection. Based on genomic sequence, this clone was extended by oligonucleotide addition to obtain minigene constructs in which the complete open reading frame (ORF) was present. Translation of the ERCC2 ORF gives an amino acid sequence that has 72% similarity with the S. cerevisiae RAD3 protein, which encodes a DNA helicase.

  8. Confinement, the Abelian Decomposition, and the Contribution of Topology to the Static Quark Potential

    E-Print Network [OSTI]

    Nigel Cundy; Yongmin Cho; Weonjong Lee

    2014-11-04

    In the past few years, we have presented a new way of considering quark confinement. Through a careful choice of a Cho-Duan-Ge Abelian Decomposition, we can construct the QCD Wilson Loop in terms of an Abelian restricted field. The relationship between the QCD and restricted string tensions is exact; and we do not need to gauge fix, apply any path ordering of gauge links, or additional path integrals. This hints at why mesons are colour neutral. Furthermore, the Abelian restricted field contains two parts: a Maxwell term, and a topological term. The topological term can describe magnetic monopoles and other topological objects, which can be studied both numerically and theoretically. By examining the topological part of the restricted field strength we have found evidence suggesting that these objects, which will contribute to confinement if present, are indeed there. Previous studies have used simplifications, breaking the exact relationship between the restricted and QCD string tensions, but it was found that the topological term dominated the restricted string tension. Here we remove those simplifications, and show that the Abelian restricted field does indeed fully explain confinement. However, our results for how much of the restricted string tension arises from the topological objects show strong dependence on the lattice spacing and level of smearing, so we are not yet able to draw a definitive conclusion.

  9. Gauge-independent "Abelian" and magnetic-monopole dominance, and the dual Meissner effect in lattice $SU(2)$ Yang-Mills theory

    E-Print Network [OSTI]

    Seikou Kato; Kei-Ichi Kondo; Akihiro Shibata

    2014-12-27

    In the $SU(2)$ Yang-Mills theory on the four-dimensional Euclidean lattice, we confirm the gauge-independent "Abelian" dominance (or the restricted field dominance) and gauge-independent magnetic-monopole dominance in the string tension of the linear potential extracted from the Wilson loop in the fundamental representation. The dual Meissner effect is observed by demonstrating the squeezing of the chromoelectric field flux connecting a pair of quark and antiquark. In addition, the circular magnetic-monopole current is induced around the chromoelectric flux. The type of the dual superconductivity is also determined by fitting the result with the dual Ginzburg-Landau model. Thus the dual superconductor picture for quark confinement is supported in a gauge-independent manner. These results are obtained based on a reformulation of the lattice Yang-Mills theory based on the change of variables a la Cho-Duan-Ge-Faddeev-Niemi combined with a non-Abelian Stokes theorem for the Wilson loop operator. We give a new procedure (called the reduction) for obtaining the color direction field which plays the central role in this reformulation.

  10. Topological configurations of Yang-Mills field responsible for magnetic-monopole loops as quark confiner

    E-Print Network [OSTI]

    Akihiro Shibata; Kei-Ichi Kondo; Seikou Kato; Shoichi Ito; Toru Shinohara; Nobuyui Fukui

    2009-11-24

    We have given a new description of the lattice Yang-Mills theory a la Cho-Faddeev-Niemi-Shabanov, which has enabled us to confirm in a gauge-independent manner "Abelian"-dominance and magnetic-monopole dominance in the Wilson loop average, yielding a gauge-independent dual superconductor picture for quark confinement. In particular, we have given a new procedure (called reduction) for obtaining a gauge-independent magnetic monopole from a given Yang-Mills field. In this talk, we demonstrate how some of known topological configurations in the SU(2) Yang-Mills theory such as merons and instantons generate closed loops of magnetic-monopole current as the quark confiner, both of which are characterized by the gauge-invariant topological index, topological charge (density) and magnetic charge (density), respectively. We also try to detect which type of topological configurations exist in the lattice data involving magnetic-monopole loops generated by Monte Carlo simulation. Here we apply a new geometrical algorithm based on "computational homology" to discriminating each closed loop from clusters of magnetic-monopole current, since the magnetic-monopole current on a lattice is integer valued.

  11. Cholesterol accumulation in Niemann Pick type C (NPC) model cells causes a shift in APP localization to lipid rafts

    SciTech Connect (OSTI)

    Kosicek, Marko; Malnar, Martina; Goate, Alison; Hecimovic, Silva

    2010-03-12

    It has been suggested that cholesterol may modulate amyloid-{beta} (A{beta}) formation, a causative factor of Alzheimer's disease (AD), by regulating distribution of the three key proteins in the pathogenesis of AD ({beta}-amyloid precursor protein (APP), {beta}-secretase (BACE1) and/or presenilin 1 (PS1)) within lipid rafts. In this work we tested whether cholesterol accumulation upon NPC1 dysfunction, which causes Niemann Pick type C disease (NPC), causes increased partitioning of APP into lipid rafts leading to increased CTF/A{beta} formation in these cholesterol-rich membrane microdomains. To test this we used CHO NPC1{sup -/-} cells (NPC cells) and parental CHOwt cells. By sucrose density gradient centrifugation we observed a shift in fl-APP/CTF compartmentalization into lipid raft fractions upon cholesterol accumulation in NPC vs. wt cells. Furthermore, {gamma}-secretase inhibitor treatment significantly increased fl-APP/CTF distribution in raft fractions in NPC vs. wt cells, suggesting that upon cholesterol accumulation in NPC1-null cells increased formation of APP-CTF and its increased processing towards A{beta} occurs in lipid rafts. Our results support that cholesterol overload, such as in NPC disease, leads to increased partitioning of APP/CTF into lipid rafts resulting in increased amyloidogenic processing of APP in these cholesterol-rich membranes. This work adds to the mechanism of the cholesterol-effect on APP processing and the pathogenesis of Alzheimer's disease and supports the role of lipid rafts in these processes.

  12. Adaptive nonlocal means filtering based on local noise level for CT denoising

    SciTech Connect (OSTI)

    Li, Zhoubo; Trzasko, Joshua D.; Lake, David S.; Blezek, Daniel J.; Manduca, Armando; Yu, Lifeng; Fletcher, Joel G.; McCollough, Cynthia H.

    2014-01-15

    Purpose: To develop and evaluate an image-domain noise reduction method based on a modified nonlocal means (NLM) algorithm that is adaptive to local noise level of CT images and to implement this method in a time frame consistent with clinical workflow. Methods: A computationally efficient technique for local noise estimation directly from CT images was developed. A forward projection, based on a 2D fan-beam approximation, was used to generate the projection data, with a noise model incorporating the effects of the bowtie filter and automatic exposure control. The noise propagation from projection data to images was analytically derived. The analytical noise map was validated using repeated scans of a phantom. A 3D NLM denoising algorithm was modified to adapt its denoising strength locally based on this noise map. The performance of this adaptive NLM filter was evaluated in phantom studies in terms of in-plane and cross-plane high-contrast spatial resolution, noise power spectrum (NPS), subjective low-contrast spatial resolution using the American College of Radiology (ACR) accreditation phantom, and objective low-contrast spatial resolution using a channelized Hotelling model observer (CHO). Graphical processing units (GPU) implementation of this noise map calculation and the adaptive NLM filtering were developed to meet demands of clinical workflow. Adaptive NLM was piloted on lower dose scans in clinical practice. Results: The local noise level estimation matches the noise distribution determined from multiple repetitive scans of a phantom, demonstrated by small variations in the ratio map between the analytical noise map and the one calculated from repeated scans. The phantom studies demonstrated that the adaptive NLM filter can reduce noise substantially without degrading the high-contrast spatial resolution, as illustrated by modulation transfer function and slice sensitivity profile results. The NPS results show that adaptive NLM denoising preserves the shape and peak frequency of the noise power spectrum better than commercial smoothing kernels, and indicate that the spatial resolution at low contrast levels is not significantly degraded. Both the subjective evaluation using the ACR phantom and the objective evaluation on a low-contrast detection task using a CHO model observer demonstrate an improvement on low-contrast performance. The GPU implementation can process and transfer 300 slice images within 5 min. On patient data, the adaptive NLM algorithm provides more effective denoising of CT data throughout a volume than standard NLM, and may allow significant lowering of radiation dose. After a two week pilot study of lower dose CT urography and CT enterography exams, both GI and GU radiology groups elected to proceed with permanent implementation of adaptive NLM in their GI and GU CT practices. Conclusions: This work describes and validates a computationally efficient technique for noise map estimation directly from CT images, and an adaptive NLM filtering based on this noise map, on phantom and patient data. Both the noise map calculation and the adaptive NLM filtering can be performed in times that allow integration with clinical workflow. The adaptive NLM algorithm provides effective denoising of CT data throughout a volume, and may allow significant lowering of radiation dose.

  13. An Exocyclic Methylene Group Acts As a Bioisostere of the 2?-Oxygen Atom in LNA

    SciTech Connect (OSTI)

    Seth, Punit P.; Allerson, Charles R.; Berdeja, Andres; Siwkowski, Andrew; Pallan, Pradeep S.; Gaus, Hans; Prakash, Thazha P.; Watt, Andrew T.; Egli, Martin; Swayze, Eric E.

    2010-12-07

    We show for the first time that it is possible to obtain LNA-like (Locked Nucleic Acid 1) binding affinity and biological activity with carbocyclic LNA (cLNA) analogs by replacing the 2{prime}-oxygen atom in LNA with an exocyclic methylene group. Synthesis of the methylene-cLNA nucleoside was accomplished by an intramolecular cyclization reaction between a radical at the 2{prime}-position and a propynyl group at the C-4{prime} position. Only methylene-cLNA modified oligonucleotides showed similar thermal stability and mismatch discrimination properties for complementary nucleic acids as LNA. In contrast, the close structurally related methyl-cLNA analogs showed diminished hybridization properties. Analysis of crystal structures of cLNA modified self-complementary DNA decamer duplexes revealed that the methylene group participates in a tight interaction with a 2{prime}-deoxyribose residue of the 5{prime}-terminal G of a neighboring duplex, resulting in the formation of a CH...O type hydrogen bond. This indicates that the methylene group retains a negative polarization at the edge of the minor groove in the absence of a hydrophilic 2{prime}-substituent and provides a rationale for the superior thermal stability of this modification. In animal experiments, methylene-cLNA antisense oligonucleotides (ASOs) showed similar in vivo activity but reduced toxicity as compared to LNA ASOs. Our work highlights the interchangeable role of oxygen and unsaturated moieties in nucleic acid structure and emphasizes greater use of this bioisostere to improve the properties of nucleic acids for therapeutic and diagnostic applications.

  14. Cesium in rock-water interaction, Yellowstone National Park. [Abstract only

    SciTech Connect (OSTI)

    Thompson, J.M.; Keith, T.E.C.

    1983-03-01

    Chemical analyses of thermal waters from research drill holes and nearby hot springs and geysers in Upper and Lower Geyser Basins indicate that Cs may be a reactive ion. A nearly constant Cs:Cl is found for four wells drilled in Lower Geyser Basin and for some hot spring and geysers. It is inferred from this plot that points falling below the trend indicate Cs depleted waters. A plot of Cs:CHO/sub 3//Cl, another measure of rock-water interaction, also indicates Cs removal from the waters. These data correlate well with a parallel study of chemistry and mineralogy of hydrothermally altered rocks from the drill holes which show that the rocks involved in hydrothermal rock-water reactions are vitrophyric rhyolite lava flows and pumiceous tuff overlain by obsidian-rich sands and gravels. Nearly 55 m of such a section from well Y-8 has been hydrothermally altered into alternating intervals consisting of analcime - quartz - clay (smectite, celadonite) or clinoptilolite - ..cap alpha..-cristobalite - smectite. Whole rock analyses of randomly selected samples of these intervals from several wells have Cs contents somewhat higher than those of the unaltered host rhyolite. However, the Cs content of the analcime - quartz - clay intervals is as much as 700 times higher than that of the host rock. Analyses of mineral separates show that analcime, containing as much as 4700 ppM Cs, is more enriched in Cs than any other mineral. Examination of experimental data suggests that Cs is incorporated into the analcime structure during crystallization. Clinoptilolite, which has been shown to readily exchange Cs, is only slightly enriched in this system.

  15. The Static Quark Potential from the Gauge Independent Abelian Decomposition

    E-Print Network [OSTI]

    Nigel Cundy; Y. M. Cho; Weonjong Lee

    2015-03-24

    We investigate the relationship between colour confinement and the gauge independent Cho-Duan-Ge Abelian decomposition. The decomposition is defined in terms of a colour field $n$; the principle novelty of our study is that we have defined this field in terms of the eigenvectors of the Wilson Loop. This establishes an equivalence between the path ordered integral of the non-Abelian gauge fields with an integral over an Abelian restricted gauge field which is tractable both theoretically and numerically in lattice QCD. We circumvent path ordering without needing an additional path integral. By using Stokes' theorem, we can compute the Wilson Loop in terms of a surface integral over a restricted field strength, and show that the restricted field strength may be dominated by certain structures, which occur when one of the quantities parametrising the colour field $n$ winds itself around a non-analyticity in the colour field. If they exist, these structures will lead to a area law scaling for the Wilson Loop and provide a mechanism for quark confinement. We search for these structures in quenched lattice QCD. We perform the Abelian decomposition, and compare the electric and magnetic fields with the patterns expected theoretically. We find that the restricted field strength is dominated by objects which may be peaks a single lattice spacing in size or extended string-like lines of electromagnetic flux. The objects are not isolated monopoles, as they generate electric fields in addition to magnetic fields, and the fields are not spherically symmetric, but may be either caused by a monopole/anti-monopole condensate, some other types of topological objects or a combination of these. Removing these peaks removes the area law scaling of the string tension, suggesting that they are responsible for confinement.

  16. ELECTRON IRRADIATION OF KUIPER BELT SURFACE ICES: TERNARY N{sub 2}-CH{sub 4}-CO MIXTURES AS A CASE STUDY

    SciTech Connect (OSTI)

    Kim, Y. S.; Kaiser, R. I.

    2012-10-10

    The space weathering of icy Kuiper Belt Objects was investigated in this case study by exposing methane (CH{sub 4}) and carbon monoxide (CO) doped nitrogen (N{sub 2}) ices at 10 K to ionizing radiation in the form of energetic electrons. Online and in situ Fourier transform infrared spectroscopy was utilized to monitor the radiation-induced chemical processing of these ices. Along with isocyanic acid (HNCO), the products could be mainly derived from those formed in irradiated binary ices of the N{sub 2}-CH{sub 4} and CO-CH{sub 4} systems: nitrogen-bearing products were found in the form of hydrogen cyanide (HCN), hydrogen isocyanide (HNC), diazomethane (CH{sub 2}N{sub 2}), and its radical fragment (HCN{sub 2}); oxygen-bearing products were of acetaldehyde (CH{sub 3}CHO), formyl radical (HCO), and formaldehyde (H{sub 2}CO). As in the pure ices, the methyl radical (CH{sub 3}) and ethane (C{sub 2}H{sub 6}) were also detected, as were carbon dioxide (CO{sub 2}) and the azide radical (N{sub 3}). Based on the temporal evolution of the newly formed products, kinetic reaction schemes were then developed to fit the temporal profiles of the newly formed species, resulting in numerical sets of rate constants. The current study highlights important constraints on the preferential formation of isocyanic acid (HNCO) over hydrogen cyanide (HCN) and hydrogen isocyanide (HNC), thus guiding the astrobiological and chemical evolution of those distant bodies.

  17. A comparative density functional study of methanol decomposition on Cu{sub 4} and Co{sub 4} clusters.

    SciTech Connect (OSTI)

    Mehmood, F.; Greeley, J.; Zapol, P.; Curtiss, L. A.

    2010-08-12

    A density functional theory study of the decomposition of methanol on Cu{sub 4} and Co{sub 4} clusters is presented. The reaction intermediates and activation barriers have been determined for reaction steps to form H{sub 2} and CO. For both clusters, methanol decomposition initiated by C-H and O-H bond breaking was investigated. In the case of a Cu{sub 4} cluster, methanol dehydrogenation through hydroxymethyl (CH{sub 2}OH), hydroxymethylene (CHOH), formyl (CHO), and carbon monoxide (CO) is found to be slightly more favorable. For a Co{sub 4} cluster, the dehydrogenation pathway through methoxy (CH{sub 3}O) and formaldehyde (CH{sub 2}O) is slightly more favorable. Each of these pathways results in formation of CO and H{sub 2}. The Co cluster pathway is very favorable thermodynamically and kinetically for dehydrogenation. However, since CO binds strongly, it is likely to poison methanol decomposition to H{sub 2} and CO at low temperatures. In contrast, for the Cu cluster, CO poisoning is not likely to be a problem since it does not bind strongly, but the dehydrogenation steps are not energetically favorable. Pathways involving C-O bond cleavage are even less energetically favorable. The results are compared to our previous study of methanol decomposition on Pd{sub 4} and Pd{sub 8} clusters. Finally, all reaction energy changes and transition state energies, including those for the Pd clusters, are related in a linear, Broensted?Evans?Polanyi plot.

  18. Currently used pesticides and their mixtures affect the function of sex hormone receptors and aromatase enzyme activity

    SciTech Connect (OSTI)

    Kjeldsen, Lisbeth Stigaard; Ghisari, Mandana; Bonefeld-Jrgensen, Eva Cecilie, E-mail: ebj@mil.au.dk

    2013-10-15

    The endocrine-disrupting potential of pesticides is of health concern, since they are found ubiquitously in the environment and in food items. We investigated in vitro effects on estrogen receptor (ER) and androgen receptor (AR) transactivity, and aromatase enzyme activity, of the following pesticides: 2-methyl-4-chlorophenoxyacetic acid (MCPA), terbuthylazine, iodosulfuron-methyl-sodium, mesosulfuron-methyl, metsulfuron-methyl, chlormequat chloride, bitertanol, propiconazole, prothioconazole, mancozeb, cypermethrin, tau fluvalinate, malathion and the metabolite ethylene thiourea (ETU). The pesticides were analyzed alone and in selected mixtures. Effects of the pesticides on ER and AR function were assessed in human breast carcinoma MVLN cells and hamster ovary CHO-K1 cells, respectively, using luciferase reporter gene assays. Effects on aromatase enzyme activity were analyzed in human choriocarcinoma JEG-3 cells, employing the classical [{sup 3}H]{sub 2}O method. Five pesticides (terbuthylazine, propiconazole, prothioconazole, cypermethrin and malathion) weakly induced the ER transactivity, and three pesticides (bitertanol, propiconazole and mancozeb) antagonized the AR activity in a concentration-dependent manner. Three pesticides (terbuthylazine, propiconazole and prothioconazole) weakly induced the aromatase activity. In addition, two mixtures, consisting of three pesticides (bitertanol, propiconazole, cypermethrin) and five pesticides (terbuthylazine, bitertanol, propiconazole, cypermethrin, malathion), respectively, induced the ER transactivity and aromatase activity, and additively antagonized the AR transactivity. In conclusion, our data suggest that currently used pesticides possess endocrine-disrupting potential in vitro which can be mediated via ER, AR and aromatase activities. The observed mixture effects emphasize the importance of considering the combined action of pesticides in order to assure proper estimations of related health effect risks. - Highlights: Currently used pesticides possess endocrine-disrupting (ED) potential in vitro. ED effects can be mediated via sex hormone receptors and/or the aromatase enzyme. Additive mixture effects on androgen receptor transactivity were observed.

  19. Quark confinement: dual superconductor picture based on a non-Abelian Stokes theorem and reformulations of Yang-Mills theory

    E-Print Network [OSTI]

    Kei-Ichi Kondo; Seikou Kato; Akihiro Shibata; Toru Shinohara

    2015-05-26

    The purpose of this paper is to review the recent progress in understanding quark confinement. The emphasis of this review is placed on how to obtain a manifestly gauge-independent picture for quark confinement supporting the dual superconductivity in the Yang-Mills theory, which should be compared with the Abelian projection proposed by 't Hooft. The basic tools are novel reformulations of the Yang-Mills theory based on change of variables extending the decomposition of the $SU(N)$ Yang-Mills field due to Cho, Duan-Ge and Faddeev-Niemi, together with the combined use of extended versions of the Diakonov-Petrov version of the non-Abelian Stokes theorem for the $SU(N)$ Wilson loop operator. Moreover, we give the lattice gauge theoretical versions of the reformulation of the Yang-Mills theory which enables us to perform the numerical simulations on the lattice. In fact, we present some numerical evidences for supporting the dual superconductivity for quark confinement. The numerical simulations include the derivation of the linear potential for static interquark potential, i.e., non-vanishing string tension, in which the "Abelian" dominance and magnetic monopole dominance are established, confirmation of the dual Meissner effect by measuring the chromoelectric flux tube between quark-antiquark pair, the induced magnetic-monopole current, and the type of dual superconductivity, etc. In addition, we give a direct connection between the topological configuration of the Yang-Mills field such as instantons/merons and the magnetic monopole.

  20. Reformulations of the Yang-Mills theory toward quark confinement and mass gap

    E-Print Network [OSTI]

    Kei-Ichi Kondo; Seikou Kato; Akihiro Shibata; Toru Shinohara

    2014-12-27

    We propose the reformulations of the $SU(N)$ Yang-Mills theory toward quark confinement and mass gap. In fact, we have given a new framework for reformulating the $SU(N)$ Yang-Mills theory using new field variables. This includes the preceding works given by Cho, Faddeev and Niemi, as a special case called the maximal option in our reformulations. The advantage of our reformulations is that the original non-Abelian gauge field variables can be changed into the new field variables such that one of them called the restricted field gives the dominant contribution to quark confinement in the gauge-independent way. Our reformulations can be combined with the $SU(N)$ extension of the Diakonov-Petrov version of the non-Abelian Stokes theorem for the Wilson loop operator to give a gauge-invariant definition for the magnetic monopole in the $SU(N)$ Yang-Mills theory without the scalar field. In the so-called minimal option, especially, the restricted field is non-Abelian and involves the non-Abelian magnetic monopole with the stability group $U(N-1)$. This suggests the non-Abelian dual superconductivity picture for quark confinement. This should be compared with the maximal option: the restricted field is Abelian and involves only the Abelian magnetic monopoles with the stability group $U(1)^{N-1}$, just like the Abelian projection. We give some applications of this reformulation, e.g., the stability for the homogeneous chromomagnetic condensation of the Savvidy type, the large N treatment for deriving the dimensional transmutation and understanding the mass gap, and also the numerical simulations on a lattice which are given by Dr. Shibata in a subsequent talk.

  1. Anion Coordination in Metal-Organic Frameworks Functionalized with Urea Hydrogen-Bonding Groups

    SciTech Connect (OSTI)

    Custelcean, Radu; Moyer, Bruce A.; Bryantsev, Vyacheslav; Hay, Benjamin P.

    2005-12-15

    A series of metal-organic frameworks (MOFs) functionalized with urea hydrogen-bonding groups have been designed, synthesized, and structurally analyzed by single crystal X-ray diffraction to evaluate the efficacy of anion binding within the structural constraints of the MOFs. We found that urea-based functionalities may be used for anion binding within metal-organic frameworks when the tendency for urea???urea self-association is decreased by strengthening the intramolelcular CH???O hydrogen bonding of N-phenyl substituents to the carbonyl oxygen atom. Theoretical calculations indicate that N,N?-bis(m-pyridyl)urea (BPU) and N,N?-bis(m-cyanophenyl)urea (BCPU) should have enhanced hydrogen-bonding donor abilities toward anions and decreased tendencies to self-associate into hydrogen-bonded chains compared to other disubstituted ureas. Accordingly, BPU and BCPU were incorporated in MOFs as linkers through coordination of various Zn, Cu, and Ag transition metal salts, including Zn(ClO4)2, ZnSO4, Cu(NO3)2, Cu(CF3SO3)2, AgNO3 and AgSO3CH3. Structural analysis by single-crystal X-ray diffraction showed that these linkers are versatile anion binders, capable of chelate hydrogen bonding to all of the oxoanions explored. Anion binding by the urea functionalities was found to successfully compete with urea self-association in all cases except for that of charge-diffuse perchlorate. This research was sponsored by the Division of Chemical Sciences, Geosciences, and Biosciences, Office of Basic Energy Sciences of the U.S. Department of Energy, under contract number DE-AC05-00OR22725 with Oak Ridge National Laboratory (managed by UT-Battelle, LLC), and performed at Oak Ridge National laboratory and Pacific Northwest National Laboratory (managed by Battelle for the U.S. Department of Energy under contract DE-AC05-76RL01830). This research was performed in part using the Molecular Science Computing Facility (MSCF) in the William R. Wiley Environmental Molecular Sciences laboratory, a national scientific user facility sponsored by the U.S. Department of Energy's Office of Biological and Environmental Research located at the Pacific Northwest National Laboratory.

  2. Structural insights into the specific anti-HIV property of actinohivin: structure of its complex with the ?(12)mannobiose moiety of gp120

    SciTech Connect (OSTI)

    Hoque, M. Mominul [Iwaki Meisei University, 5-5-1 Chuodai-Iino, Iwaki, Fukushima 970-8551 (Japan); Rajshahi University, Rajshahi (Bangladesh); Suzuki, Kaoru [Iwaki Meisei University, Iwaki, Fukushima 970-8551 (Japan); Tsunoda, Masaru; Jiang, Jiandong; Zhang, Fang; Takahashi, Atsushi; Ohbayashi, Naomi; Zhang, Xiaoxue [Iwaki Meisei University, 5-5-1 Chuodai-Iino, Iwaki, Fukushima 970-8551 (Japan); Tanaka, Haruo [Iwaki Meisei University, 5-5-1 Chuodai-Iino, Iwaki, Fukushima 970-8551 (Japan); Iwaki Meisei University, 5-5-1 Chuodai-Iino, Iwaki, Fukushima 970-8551 (Japan); KIIM Pharmaceutical Laboratories Inc., Fukushima 970-8551 (Japan); ?mura, Satoshi [Kitasato University, Tokyo 108-8641 (Japan); Taknaka, Akio, E-mail: atakenak@sakura.email.ne.jp [Iwaki Meisei University, 5-5-1 Chuodai-Iino, Iwaki, Fukushima 970-8551 (Japan); Iwaki Meisei University, 5-5-1 Chuodai-Iino, Iwaki, Fukushima 970-8551 (Japan); Tokyo Institute of Technology, Yokohama 226-8501 (Japan)

    2012-12-01

    X-ray analysis of anti-HIV actinohivin in complex with the target ?(1-2)mannobiose moiety of high-mannose type glycans attached to HIV-1 gp120 reveals that the three rotamers generated with 120 rotations around the molecular pseudo-rotation axis are packed randomly in the unit cell according to the P2{sub 1}2{sub 1}2{sub 1} symmetry to exhibit an apparent space group P2{sub 1}3 as the statistical structure. However, the high-resolution X-ray structure shows the detailed interaction geometry for specific binding. Actinohivin (AH) is an actinomycete lectin with a potent specific anti-HIV activity. In order to clarify the structural evidence for its specific binding to the ?(12)mannobiose (MB) moiety of the D1 chains of high-mannose-type glycans (HMTGs) attached to HIV-1 gp120, the crystal structure of AH in complex with MB has been determined. The AH molecule is composed of three identical structural modules, each of which has a pocket in which an MB molecule is bound adopting a bracket-shaped conformation. This conformation is stabilized through two weak CH?O hydrogen bonds facilitated by the ?(12) linkage. The binding features in the three pockets are quite similar to each other, in accordance with the molecular pseudo-threefold symmetry generated from the three tandem repeats in the amino-acid sequence. The shape of the pocket can accept two neighbouring hydroxyl groups of the O{sup 3} and O{sup 4} atoms of the equatorial configuration of the second mannose residue. To recognize these atoms through hydrogen bonds, an Asp residue is located at the bottom of each pocket. Tyr and Leu residues seem to block the movement of the MB molecules. Furthermore, the O{sup 1} atom of the axial configuration of the second mannose residue protrudes from each pocket into an open space surrounded by the conserved hydrophobic residues, suggesting an additional binding site for the third mannose residue of the branched D1 chain of HMTGs. These structural features provide strong evidence indicating that AH is only highly specific for MB and would facilitate the highly specific affinity of AH for any glycoprotein carrying many HMTGs, such as HIV-1 gp120.

  3. FEEDSTOCK-FLEXIBLE REFORMER SYSTEM (FFRS) FOR SOLID OXIDE FUEL CELL (SOFC)- QUALITY SYNGAS

    SciTech Connect (OSTI)

    Kelly Jezierski; Andrew Tadd; Johannes Schwank; Roland Kibler; David McLean; Mahesh Samineni; Ryan Smith; Sameer Parvathikar; Joe Mayne; Tom Westrich; Jerry Mader; F. Michael Faubert

    2010-07-30

    The U.S. Department of Energy National Energy Technology Laboratory funded this research collaboration effort between NextEnergy and the University of Michigan, who successfully designed, built, and tested a reformer system, which produced highquality syngas for use in SOFC and other applications, and a novel reactor system, which allowed for facile illumination of photocatalysts. Carbon and raw biomass gasification, sulfur tolerance of non-Platinum Group Metals (PGM) based (Ni/CeZrO2) reforming catalysts, photocatalysis reactions based on TiO2, and mild pyrolysis of biomass in ionic liquids (ILs) were investigated at low and medium temperatures (primarily 450 to 850 C) in an attempt to retain some structural value of the starting biomass. Despite a wide range of processes and feedstock composition, a literature survey showed that, gasifier products had narrow variation in composition, a restriction used to develop operating schemes for syngas cleanup. Three distinct reaction conditions were investigated: equilibrium, autothermal reforming of hydrocarbons, and the addition of O2 and steam to match the final (C/H/O) composition. Initial results showed rapid and significant deactivation of Ni/CeZrO2 catalysts upon introduction of thiophene, but both stable and unstable performance in the presence of sulfur were obtained. The key linkage appeared to be the hydrodesulfurization activity of the Ni reforming catalysts. For feed stoichiometries where high H2 production was thermodynamically favored, stable, albeit lower, H2 and CO production were obtained; but lower thermodynamic H2 concentrations resulted in continued catalyst deactivation and eventual poisoning. High H2 levels resulted in thiophene converting to H2S and S surface desorption, leading to stable performance; low H2 levels resulted in unconverted S and loss in H2 and CO production, as well as loss in thiophene conversion. Bimetallic catalysts did not outperform Ni-only catalysts, and small Ni particles were found to have lower activities under S-free conditions, but did show less effect of S on performance, in this study. Imidazolium-based ILs, choline chloride compounds and low-melting eutectics of metal nitrates were evaluated, and it was found that, ILs have some capacity to dissolve cellulose and show thermal stability to temperatures where pyrolysis begins, have no vapor pressure, (simplifying product recoveries), and can dissolve ionic metal salts, allowing for the potential of catalytic reactions on breakdown intermediates. Clear evidence of photoactive commercial TiO2 was obtained, but in-house synthesis of photoactive TiO2 proved difficult, as did fixed-bed gasification, primarily due to the challenge of removing the condensable products from the reaction zone quickly enough to prevent additional reaction. Further investigation into additional non-PGM catalysts and ILs is recommended as a follow-up to this work.

  4. Bulk gold catalyzed oxidation reactions of amines and isocyanides and iron porphyrin catalyzed N-H and O-H bond insertion/cyclization reactions of diamines and aminoalcohols

    SciTech Connect (OSTI)

    Klobukowski, Erik

    2011-12-29

    This work involves two projects. The first project entails the study of bulk gold as a catalyst in oxidation reactions of isocyanides and amines. The main goal of this project was to study the activation and reactions of molecules at metal surfaces in order to assess how organometallic principles for homogeneous processes apply to heterogeneous catalysis. Since previous work had used oxygen as an oxidant in bulk gold catalyzed reactions, the generality of gold catalysis with other oxidants was examined. Amine N-oxides were chosen for study, due to their properties and use in the oxidation of carbonyl ligands in organometallic complexes. When amine N-oxides were used as an oxidant in the reaction of isocyanides with amines, the system was able to produce ureas from a variety of isocyanides, amines, and amine N-oxides. In addition, the rate was found to generally increase as the amine N-oxide concentration increased, and decrease with increased concentrations of the amine. Mechanistic studies revealed that the reaction likely involves transfer of an oxygen atom from the amine N-oxide to the adsorbed isocyanide to generate an isocyanate intermediate. Subsequent nucleophilic attack by the amine yields the urea. This is in contrast to the bulk gold-catalyzed reaction mechanism of isocyanides with amines and oxygen. Formation of urea in this case was proposed to proceed through a diaminocarbene intermediate. Moreover, formation of the proposed isocyanate intermediate is consistent with the reactions of metal carbonyl ligands, which are isoelectronic to isocyanides. Nucleophilic attack at coordinated CO by amine N-oxides produces CO{sub 2} and is analogous to the production of an isocyanate in this gold system. When the bulk gold-catalyzed oxidative dehydrogenation of amines was examined with amine N-oxides, the same products were afforded as when O{sub 2} was used as the oxidant. When the two types of oxidants were directly compared using the same reaction system and conditions, it was found that the oxidative dehydrogenation of dibenzylamine to Nbenzylidenebenzylamine, with N-methylmorpholine N-oxide (NMMO), was nearly quantitative (96%) within 24 h. However, the reaction with oxygen was much slower, with only a 52% yield of imine product over the same time period. Moreover, the rate of reaction was found to be influenced by the nature of the amine N-oxide. For example, the use of the weakly basic pyridine N-oxide (PyNO) led to an imine yield of only 6% after 24 h. A comparison of amine N-oxide and O2 was also examined in the oxidation of PhCH{sub 2}OH to PhCHO catalyzed by bulk gold. In this reaction, a 52% yield of the aldehyde was achieved when NMMO was used, while only a 7% product yield was afforded when O{sub 2} was the oxidant after 48 h. The bulk gold-catalyzed oxidative dehydrogenation of cyclic amines generates amidines, which upon treatment with Aerosil and water were found to undergo hydrolysis to produce lactams. Moreover, 5-, 6-, and 7-membered lactams could be prepared through a one-pot reaction of cyclic amines by treatment with oxygen, water, bulk gold, and Aerosil. This method is much more atom economical than industrial processes, does not require corrosive acids, and does not generate undesired byproducts. Additionally, the gold and Aerosil catalysts can be readily separated from the reaction mixture. The second project involved studying iron(III) tetraphenylporphyrin chloride, Fe(TPP)Cl, as a homogeneous catalyst for the generation of carbenes from diazo reagents and their reaction with heteroatom compounds. Fe(TPP)Cl, efficiently catalyzed the insertion of carbenes derived from methyl 2-phenyldiazoacetates into O-H bonds of aliphatic and aromatic alcohols. Fe(TPP)Cl was also found to be an effective catalyst for tandem N-H and O-H insertion/cyclization reactions when 1,2-diamines and 1,2-alcoholamines were treated with diazo reagents. This approach provides a one-pot process for synthesizing piperazinones and morpholinones and related analogues such as quinoxalinones and benzoxazin-2-ones.