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Sample records for involving older drivers

  1. Projecting Fatalities in Crashes Involving Older Drivers, 20002025

    E-Print Network [OSTI]

    ORNL-6963 Projecting Fatalities in Crashes Involving Older Drivers, 2000­2025 Patricia S. Hu 2000 This research was funded by GM pursuant to an agreement between GM and the U.S. Department #12;#12;GM Project G.6 October 2000iii TABLE OF CONTENTS LIST OF FIGURES

  2. Projecting Fatalities in Crashes Involving Older Drivers, 2000–2025, CRADA No. ORNL98-0500 Final Report

    SciTech Connect (OSTI)

    Hu, Patricia S. [ORNL] [ORNL; Jones, Donald W. [ORNL] [ORNL; Reuscher, Timothy [Oak Ridge Institute for Science and Education] [Oak Ridge Institute for Science and Education; Schmoyer, Richard S. [ORNL] [ORNL; Truett, Lorena F. [ORNL] [ORNL

    2000-04-01

    At the turn of the century – the 20th century that is – the median age in the United States was under 30 years; America was 60% rural in nature; and there were only 36 highway fatalities all year. As we leave the 20th century behind, the route into the 21st century is very different. “Intelligent” cars speed down multi-lane “smart” highways in a nation that is 75% urban. According to the Federal Highway Administration’s Highway Statistics, there are 28,000 times more vehicles on the road in 2000 than there were in 1900, and these vehicles travel about 2.6 trillion miles each year. Annual fatalities resulting from highway crashes have also increased – by over 1100%. We see other changes as well. The face of America is changing. It is growing older. In 2025, persons 65 and over will make up 18.5% of the total population. The number of persons aged 85 and over is increasing more rapidly than any other age group. More importantly, the elderly are taking more trips, driving further, and continuing to drive much later in life. These conditions lead to concerns about traffic safety. Although the elderly are healthier and drive safer cars than they did just two decades ago, their frailty makes them more susceptible to injury than younger persons involved in traffic crashes of the same severity. In addition, visual, physical, and cognitive skills, all of which contribute to driving abilities, decrease with advancing age. The familiar “U”-shaped curve depicting the rate of fatalities per vehicle miles traveled, shows that the elderly experience a higher highway fatality rate than any other age group except teenagers. While the overall number of highway fatalities has decreased regularly since 1972, the number of fatalities of elderly travelers has continued to increase steadily. This increase is cause for concern for both the elderly driver and for other persons on the roads who migh tbe placed in danger through crashes involving elderly drivers.

  3. Assessment of older driver understanding of certain traffic control devices in Texas 

    E-Print Network [OSTI]

    Hulett, Stephanie Renee

    2000-01-01

    The purpose of this research was to assess older Texas drivers on their understanding of nine traffic control devices and identify the devices that are misunderstood by people 65 years and older. Additionally, older ...

  4. Older Emergency Department Drivers: Patterns, Behaviors, and Willingness to Enroll in a Safe Driver Program

    E-Print Network [OSTI]

    Stiffler, Kirk A; Wilber, Scott T

    2011-01-01

    of Address for Correspondence: Kirk A. Stiffler, MD, Summain a Safe Driver Program Kirk A. Stiffler, MD Scott T.

  5. Early User Involvement in the Development of Information Technology-Related Products for Older People

    E-Print Network [OSTI]

    Eisma, R.; Dickinson, A.; Goodman, J.

    Eisma,R. Dickinson,A. Goodman,J. Syme,A. Tiwari,L. Newell,A. Universal Access in the Information Society,Special Issue on Design Principles to Support Older Adults pp 131-140 Springer

  6. 9. Driver's Age 13. Driver's Date of Birth 14. Driver's Social Security Number 19. Driver's Telephone

    E-Print Network [OSTI]

    Gering, Jon C.

    of Accident (city, state; if on a highway, give number and nearest community) DRIVER INFORMATION OTHER VEHICLE OR PROPERTY Occupied Unoccupied 17. Driver's Age VEHICLE OPERATED BY UNIVERSITY EMPLOYEE Occupied Unoccupied 8. Driver's Name 16. Driver's Name TRUMAN STATE UNIVERSITY VEHICLE ACCIDENT REPORT NAME AND ADDRESS AREA

  7. Efficacy, national/international practices and motivational factors of lifelong driver education for the aging population

    E-Print Network [OSTI]

    Israels, Richard (Richard Steven)

    2006-01-01

    In a society facing a significant increase in its aging population, older driver education/training is emerging as a potential solution to help seniors drive more safely, thus maintaining their mobility and quality of life. ...

  8. Using Vehicular Communication to Support Older Drivers at Road Intersections

    E-Print Network [OSTI]

    Aberg, Johan

    reasoning systems (ECAM) this accident setting is analyzed in depth, and the potential for accident only on sensors placed on the vehicle. More specifically, we use a temporal reasoning system (ECAM

  9. Alternative highway sign alphabet styles for older drivers 

    E-Print Network [OSTI]

    Tan, Carol Hannah

    1991-01-01

    70 72 80 82 84 105 VITA 121 LIST OF FIGURES Figure 1. Structural Components of Letters 2. Example of Test Regulatory Sign 3. Example of Test Warning Sign 4. Example of Test Guide Sign 5. Examples of Typefaces Used in Experiment 6... 51 LIST OF TABLES Table 1. 2. 3. 4. 5. 7. 8. 9 Legibility Scales Legibility of Standard Letter Series Age and Gender Distribution of Subjects Mean Legibility Distances for Regulatory Signs. . . Mean Font Legibility (ft. /in...

  10. Market Drivers for Biofuels | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Market Drivers for Biofuels Market Drivers for Biofuels This presentation, entitled "Market Drivers for Biofuels," was given at the Third Annual MSW to Biofuels Summit in February,...

  11. Drivers, Trends and Mitigation

    SciTech Connect (OSTI)

    Blanco, Arthur S.; Gerlagh, Reyer; Suh, Sangwon; Barrett, John A.; de Coninck, Heleen; Diaz Morejon, Cristobal Felix; Mathur, Ritu; Nakicenovic, Nebojsa; Ahenkorah, Alfred Ofosu; Pan, Jiahua; Pathak, Himanshu; Rice, Jake; Richels, Richard G.; Smith, Steven J.; Stern, David; Toth, Ferenc L.; Zhou, Peter

    2014-12-01

    Chapter 5 analyzes the anthropogenic greenhouse gas (GHG) emission trends until the present and the main drivers that explain those trends. The chapter uses different perspectives to analyze past GHG-emissions trends, including aggregate emissions flows and per capita emissions, cumulative emissions, sectoral emissions, and territory-based vs. consumption-based emissions. In all cases, global and regional trends are analyzed. Where appropriate, the emission trends are contextualized with long-term historic developments in GHG emissions extending back to 1750.

  12. Approaches to enhance driver situational assessment aids

    E-Print Network [OSTI]

    Jones, Eric M. (Eric Michael)

    2007-01-01

    Collision warning systems encounter a fundamental trade-off between providing the driver more time in which to respond and alerting the driver unnecessarily. The probability that a driver successfully avoids a hazard ...

  13. The Static Driver Verifier Research Platform

    E-Print Network [OSTI]

    Rajamani, Sriram K.

    of Bebop! #12;Device Driver Interface KeAcquire SpinLock KeRelease SpinLock Driver Entry Point I/O Manager Device Driver Interface Model KeAcquire SpinLock KeRelease SpinLock Driver Entry Point I/O Manager Model(s==locked) { abort "The driver has returned from an entry point without releasing the lock.";}} #12;Sample Driver

  14. UWB dual burst transmit driver

    DOE Patents [OSTI]

    Dallum, Gregory E. (Livermore, CA); Pratt, Garth C. (Discovery Bay, CA); Haugen, Peter C. (Livermore, CA); Zumstein, James M. (Livermore, CA); Vigars, Mark L. (Livermore, CA); Romero, Carlos E. (Livermore, CA)

    2012-04-17

    A dual burst transmitter for ultra-wideband (UWB) communication systems generates a pair of precisely spaced RF bursts from a single trigger event. An input trigger pulse produces two oscillator trigger pulses, an initial pulse and a delayed pulse, in a dual trigger generator. The two oscillator trigger pulses drive a gated RF burst (power output) oscillator. A bias driver circuit gates the RF output oscillator on and off and sets the RF burst packet width. The bias driver also level shifts the drive signal to the level that is required for the RF output device.

  15. Install, both Arduino and AmaSeis software programs: Installing Arduino and drivers: Setting up AmaSeis

    E-Print Network [OSTI]

    Barrash, Warren

    Install, both Arduino and AmaSeis software programs: Installing Arduino and drivers: Setting up Ama the Arduino drivers. Take note of the assigned com port number, and set up AmaSeis to that number. 3. Some computers will require the following. Keep in mind, Arduino, does not need to run or be involved. You just

  16. Parent Involvement 

    E-Print Network [OSTI]

    Howard, Jeff W.

    2005-05-10

    To be successful, a 4-H program must have parent involvement. Although 4-H leaders and Extension agents may interest young people in becoming members, they need the parents' goodwill and support to keep them interested, ...

  17. Drivers of Future Energy Demand

    Gasoline and Diesel Fuel Update (EIA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustments (Billion Cubic Feet) Wyoming Dry NaturalPrices1 Table272/S The National Interim7141. Total3.9Drivers

  18. Design consistency and driver error as reflected by driver workload and accident rates 

    E-Print Network [OSTI]

    Wooldridge, Mark Douglas

    1992-01-01

    DESIGN CONSISTENCY AND DRIVER ERROR AS REFLECTED BY DRIVER WORKLOAD AND ACCIDENT RATES A Thesis by MARK DOUGLAS WOOLDRIDGE Approved as to style and content by: Daniel B. Fambro (Chair of Committee) Raymond A. Krammes (Member) Olga J.... Pendleton (Member) James T. P. Yao (Head of Department) May 1992 ABSTRACT Design Consistency and Driver Error as Reflected by Driver Workload and Accident Rates (May 1992) Mark Douglas Wooldridge, B. S. , Texas A&M University Chair of Advisory...

  19. Construction of a driver-vehicle model and identification of the driver model parameters 

    E-Print Network [OSTI]

    Su, Jemeng

    1981-01-01

    CONSTRUCTION OF A DRIVER-VEHICLE MODEL AND IDENTIFICATION OF THE DRIVER MODEL PARAMETERS A Thesis by , JEMENG SU Submitted to the Graduate College of Texas A8M University in partial fulfillment of the requiremr nt for the degree of MASTER... OF SCIENCE December 1981 Major Subject: Mechanical Engineering CONSTRUCTION OF A DRIVER-VEHICLE MODEL AND IDENTIFICATION OF THE DRIVER MODEL PARAMETERS A Thesis by JEMENG SU Approved as to style and content by: (Chairman of Committe ) / I...

  20. 9, 1443714473, 2012 Soil carbon drivers

    E-Print Network [OSTI]

    Ickert-Bond, Steffi

    BGD 9, 14437­14473, 2012 Soil carbon drivers and benchmarks in Earth system models K. E. O. Todd if available. Causes of variation in soil carbon predictions from CMIP5 Earth system models and comparison #12;BGD 9, 14437­14473, 2012 Soil carbon drivers and benchmarks in Earth system models K. E. O. Todd

  1. FFAG ACCELERATOR PROTON DRIVER FOR NEUTRINO FACTORY.

    SciTech Connect (OSTI)

    RUGGIERO, A.

    2005-06-21

    This paper is the summary of a conceptual study of a Proton Driver for Neutrino Factory based on the use of a Fixed-Field Alternating-Gradient (FFAG) Accelerator. The required proton energy range for an optimum neutrino production is 5 to 12 GeV. This can be accomplished with a group of three concentric rings each with 807 m circumference [1]. FFAG Accelerators [2] have the capability to accelerate charged particles over a large momentum range ({+-}30-50%) and the feature of constant bending and focusing fields. Particles can be accelerated very fast at the rate given by the accelerating field of RF cavities placed in proper locations between magnets. The performance of FFAG accelerators is to be placed between that of Super-Conducting Linear Accelerators (SCL), with which they share the fast acceleration rate, and Rapid-Cycling Synchrotrons (RCS), as they allow the beam to re-circulate over fewer revolutions. Brookhaven National Laboratory is involved in the study of feasibility of FFAG Accelerators to accelerate intense beams of protons in the GeV energy range for a variety of applications the most important of which is the Upgrade of the Alternating Gradient Synchrotron (AGS) with a new FFAG injector [3] accelerating from 400 MeV to 1.5 GeV. The ring would be housed in the AGS tunnel and has henceforth a circumference of 807 m.

  2. In-car Airway Options for NASCAR Drivers

    E-Print Network [OSTI]

    Dyreyes, Jonathan Q; Grange, Jeff; Smith, Dustin; Jin, Peter; Guldner, Greg

    2008-01-01

    Medicine Background: “Stock car” drivers may require anpresentation pregnancy. In-car Airway Options for NASCARhelmeted, and apneic stock car driver simulation model.

  3. Brazil's Biofuels Scenario: What are the Main Drivers Which will...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Brazil's Biofuels Scenario: What are the Main Drivers Which will Shape Investments in the Long Term? Brazil's Biofuels Scenario: What are the Main Drivers Which will Shape...

  4. Vehicle Technologies Office Merit Review 2015: Gate Driver Optimizatio...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Gate Driver Optimization for WBG Applications Vehicle Technologies Office Merit Review 2015: Gate Driver Optimization for WBG Applications Presentation given by Oak Ridge National...

  5. Analyzing Fuel Saving Opportunities through Driver Feedback Mechanisms...

    Office of Environmental Management (EM)

    Analyzing Fuel Saving Opportunities through Driver Feedback Mechanisms Analyzing Fuel Saving Opportunities through Driver Feedback Mechanisms 2011 DOE Hydrogen and Fuel Cells...

  6. Public Health and Older GeorgiansPublic Health and Older Georgians

    E-Print Network [OSTI]

    Arnold, Jonathan

    Public Health and Older GeorgiansPublic Health and Older Georgians:: Health DisparitiesHealth Disparities Institute of Gerontology College of Public Health The University of Georgia #12;F r o m t h e D i r e c t o r HealthDisparitiesandOlder Georgians This report continues the Public Health and Older

  7. Housing Checklist for Older Adults. 

    E-Print Network [OSTI]

    Anonymous,

    1980-01-01

    .1215 - HOUSING CHECKLIST FOR OLDER ADULTS ------ This checklist will help you evaluate a home to deter mine whether it meets the needs of the elderly and handicapped and furthers their independent living. It will also be helpful in evaluating a new house..., apart ment, mobile home or other facility for retirement living. Each statement reflects a desirable feature for the elderly and handicapped. Mark an X in the appropriate box according to the following: Yes D No D 3 Yes No LOCATION...

  8. Solar Supply Chain and Market Driver Analysis 

    E-Print Network [OSTI]

    Martinez, Nicholas 1990-

    2012-05-09

    This study aims to explore the evolution of the photovoltaic supply chain in the United States and the drivers which foster growth of the solar market. The study will gather knowledge on the growth of the solar market and ...

  9. Drawing driver's attention to potentially dangerous objects

    E-Print Network [OSTI]

    Kurugöl, Orc?un

    2008-01-01

    Drivers often have difficulties noticing potentially dangerous objects due to weather or lighting conditions or when their field of view is restricted. This thesis presents a display method for potentially dangerous objects ...

  10. Workshop on transport for a common ion driver

    SciTech Connect (OSTI)

    Olson, C.C. [Sandia National Labs., Albuquerque, NM (United States); Lee, E. [Lawrence Berkeley Lab., CA (United States); Langdon, B. [Lawrence Livermore National Lab., CA (United States)

    1994-12-31

    This report contains research in the following areas related to beam transport for a common ion driver: multi-gap acceleration; neutralization with electrons; gas neutralization; self-pinched transport; HIF and LIF transport, and relevance to common ion driver; LIF and HIF reactor concepts and relevance to common ion driver; atomic physics for common ion driver; code capabilities and needed improvement.

  11. Driver expectancy in locating automotive controls 

    E-Print Network [OSTI]

    Francis, Dawn Suzette

    1990-01-01

    DRIVER EXPECTANCY IN LOCATING AUTOMOTIVE CONTROLS A Thesis by DAWN SUZETTE FRANCIS Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE May 1990... Major Subject: Industrial Engineering DRIVER EXPECTANCY IN LOCATING AUTOMOTIVE CONTROLS A Thesis by DAWN SUZETTE FRANCIS Approved as to style and content by: R. Dale Huchi son (Chair of Committee) Rodger . . ppa (Member) Waymon L ohnston (M er...

  12. Local Danger Warnings for Drivers: The Effect of Modality and Level of Assistance on Driver Reaction

    E-Print Network [OSTI]

    Theune, Mariët

    Local Danger Warnings for Drivers: The Effect of Modality and Level of Assistance on Driver¨ucken, Germany christian.mueller@dfki.de ABSTRACT Local danger warning is an important function of Advanced presentation) is particularly crucial to a successful danger avoidance. We present a user study investigating

  13. Selected Texas Driver Education Instructors’ Feelings About A Driver Education Cultural Awareness Survey 

    E-Print Network [OSTI]

    Saint, Nina Jo

    2012-07-16

    in equitable roles,? and ?images of teenager drivers;? and (2) Instructors did not agree on how a survey instrument should be administered. iv DEDICATION This work is dedicated to the young drivers who drive me to continue to work towards ensuring... that high quality and equitable driver and traffic safety education will be offered that will provide them the knowledge and skills that they can use to avoid traffic crashes and stay alive on our roadways. In addition, this work is dedicated to traffic...

  14. Fact #574: June 8, 2009 Vehicles per Licensed Driver Rising

    Broader source: Energy.gov [DOE]

    The number of vehicles in operation per licensed driver has risen steadily since 1950. In 1985, for the first time, there was one vehicle for every licensed driver. Since 1985, the number of...

  15. Long run changes in driver behavior due to variable tolls 

    E-Print Network [OSTI]

    Konduru, Karun K.

    2004-09-30

    As many variable pricing projects are still in the implementation stage, long-run driver responses to the variable tolls are largely unknown. This research examined the long-run changes in driver behavior in an existing ...

  16. California Water and Fish: Drivers of Change

    E-Print Network [OSTI]

    Rubin, Yoram

    California Water and Fish: Drivers of Change Stephanie Carlson Assistant Professor Environmental Matters to Californians Water Supply Recreation Ecosystem Housing Agriculture Infrastructure Slide;Ecological Impacts of Delta Water Diversion/Use #12;Key Issues in the Delta 1. Water infrastructure

  17. Intercept: Profiling Windows Network Device Drivers* Manuel Mendona Nuno Neves

    E-Print Network [OSTI]

    Neves, Nuno

    testing, or reverse engineering. Experi- ments using Ethernet, Wi-Fi and Bluetooth device drivers show the device driver under test is subject to a heavy workload. Keywords. Device drivers; profiling not release openly the code, or even the hardware specifications. Therefore, the de- velopment, testing

  18. Page 1 of 3 Georgia Drivers License and

    E-Print Network [OSTI]

    Hutcheon, James M.

    Page 1 of 3 Georgia Drivers License and U.S. Social Security Card Information for International Students Do I need a Georgia driver's license or Social Security card? What are the benefits? Generally speaking, a U.S. driver's license is the most common form of day-to-day identification in the U.S. because

  19. Stress Modulates Reinforcement Learning in Younger and Older Adults Nichole R. Lighthall, Marissa A. Gorlick,

    E-Print Network [OSTI]

    Mather, Mara

    Stress Modulates Reinforcement Learning in Younger and Older Adults Nichole R. Lighthall, Marissa A that stress increases dopamine levels in brain regions involved in reward processing, and stress also appears to increase the attractiveness of addictive drugs. The current study tested the hypothesis that stress

  20. IEEE TRANSACTIONS ON MULTIMEDIA, VOL. X, NO. X, APRIL 2012 1 Modeling of Driver Behavior in Real World

    E-Print Network [OSTI]

    Busso, Carlos

    (NHTSA) indicated that over 25% of police- reported crashes involved inattentive drivers [1]. The 100-car are in a moving vehicle, they are This work was done when the authors were with Department of Electrical of Electrical Engineering, The University of Texas at Dallas, Richardson, TX, 75080 USA E-mail: busso

  1. Market Drivers for Biofuels | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious RankADVANCED MANUFACTURING OFFICESpecial Report ManagementMarine & Hydrokinetic »Market Drivers for

  2. Properties of Electricity Prices and the Drivers of Interconnector Revenue

    E-Print Network [OSTI]

    Parail, Vladimir

    Properties of Electricity Prices and the Drivers of Interconnector Revenue Vladimir Parail November 2010 CWPE 1059 & EPRG 1033 www.eprg.group.cam.ac.uk E P R G W O R K IN G P A P E R Abstract... Properties of Electricity Prices and the Drivers of Interconnector Revenue EPRG Working Paper 1033 Cambridge Working Paper in Economics 1059 Vladimir Parail This paper examines the drivers behind revenues of merchant electricity...

  3. ION ACCELERATORS AS DRIVERS FOR INERTIAL CONFINEMENT FUSION

    E-Print Network [OSTI]

    Faltens, A.

    2010-01-01

    AS DRIVERS FOR INERTIAL CONFINEMENT FUSION Andris Faltens,ENERGY PRODUCTION VIA INERTIAL CONFINEMENT FUSIONFor inertial confinement fusion (ICF) to lead to net energy

  4. Microsoft Word - ContractManagementPlanningDRIVERS.doc | Department...

    Broader source: Energy.gov (indexed) [DOE]

    ContractManagementPlanningDRIVERS.doc More Documents & Publications Microsoft Word - ARRAAttachment2.doc Microsoft Word - ARRAModelWAS.doc Microsoft Word - ARRAMOModelMod.doc...

  5. Inertially confined fusion using heavy ion drivers

    SciTech Connect (OSTI)

    Herrmannsfeldt, W.B.; Bangerter, R.O.; Bock, R.; Hogan, W.J.; Lindl, J.D.

    1991-10-01

    The various technical issues of HIF will be briefly reviewed in this paper. It will be seen that there are numerous areas in common in all the approaches to HIF. In the recent International Symposium on Heavy Ion Inertial Fusion, the attendees met in specialized workshop sessions to consider the needs for research in each area. Each of the workshop groups considered the key questions of this report: (1) Is this an appropriate time for international collaboration in HIF? (2) Which problems are most appropriate for such collaboration? (3) Can the sharing of target design information be set aside until other driver and systems issues are better resolved, by which time it might be supposed that there could be a relaxation of classification of target issues? (4) What form(s) of collaboration are most appropriate, e.g., bilateral or multilateral? (5) Can international collaboration be sensibly attempted without significant increases in funding for HIF? The authors of this report share the conviction that collaboration on a broad scale is mandatory for HIF to have the resources, both financial and personnel, to progress to a demonstration experiment. Ultimately it may be possible for a single driver with the energy, power, focusibility, and pulse shape to satisfy the needs of the international community for target physics research. Such a facility could service multiple experimental chambers with a variety of beam geometries and target concepts.

  6. Inertially confined fusion using heavy ion drivers

    SciTech Connect (OSTI)

    Herrmannsfeldt, W.B. ); Bangerter, R.O. ); Bock, R. ); Hogan, W.J.; Lindl, J.D. )

    1991-10-01

    The various technical issues of HIF will be briefly reviewed in this paper. It will be seen that there are numerous areas in common in all the approaches to HIF. In the recent International Symposium on Heavy Ion Inertial Fusion, the attendees met in specialized workshop sessions to consider the needs for research in each area. Each of the workshop groups considered the key questions of this report: (1) Is this an appropriate time for international collaboration in HIF (2) Which problems are most appropriate for such collaboration (3) Can the sharing of target design information be set aside until other driver and systems issues are better resolved, by which time it might be supposed that there could be a relaxation of classification of target issues (4) What form(s) of collaboration are most appropriate, e.g., bilateral or multilateral (5) Can international collaboration be sensibly attempted without significant increases in funding for HIF The authors of this report share the conviction that collaboration on a broad scale is mandatory for HIF to have the resources, both financial and personnel, to progress to a demonstration experiment. Ultimately it may be possible for a single driver with the energy, power, focusibility, and pulse shape to satisfy the needs of the international community for target physics research. Such a facility could service multiple experimental chambers with a variety of beam geometries and target concepts.

  7. A general probabilistic framework for volumetric articulated body pose estimation and driver gesture, activity and intent analysis for human-centric driver assistance

    E-Print Network [OSTI]

    Cheng, Shinko Yuanhsien

    2007-01-01

    Driver body-pose analysis . . . . . . . . . . . . . . . . .Body Pose Estimation . . . . . . . . . . . . . . . . .Mixture Model . . 4. Learning Pose using EM . . . . . .

  8. Risk Predictors, Outcomes, and Costs of Falls Among Older Adults Living in the Community

    E-Print Network [OSTI]

    Hoffman, Geoffrey Jonathan

    2015-01-01

    proportion of nursing home admissions among older adults areoutcomes for older adults. Orthopaedic nursing. Hartholt KA,aides, nursing aides) in efforts to help older adults better

  9. Updated 6/9/2015 Louisiana Driver's License

    E-Print Network [OSTI]

    Updated 6/9/2015 Louisiana Driver's License http://omv.dps.state.la.us/ or www on your status to be issued a driver's license, as indicated by the end date on your I-20, DS-2019 will NOT be issued a license with validity that includes the 60 or 30 grace period permitted at the end

  10. Nonlinear transmission line based electron beam driver

    SciTech Connect (OSTI)

    French, David M.; Hoff, Brad W.; Tang Wilkin; Heidger, Susan; Shiffler, Don [Directed Energy Directorate, Air Force Research Laboratory, Kirtland AFB, New Mexico 87117 (United States); Allen-Flowers, Jordan [Program in Applied Mathematics, University of Arizona, Tucson, Arizona 85721 (United States)

    2012-12-15

    Gated field emission cathodes can provide short electron pulses without the requirement of laser systems or cathode heating required by photoemission or thermionic cathodes. The large electric field requirement for field emission to take place can be achieved by using a high aspect ratio cathode with a large field enhancement factor which reduces the voltage requirement for emission. In this paper, a cathode gate driver based on the output pulse train from a nonlinear transmission line is experimentally demonstrated. The application of the pulse train to a tufted carbon fiber field emission cathode generates short electron pulses. The pulses are approximately 2 ns in duration with emission currents of several mA, and the train contains up to 6 pulses at a frequency of 100 MHz. Particle-in-cell simulation is used to predict the characteristic of the current pulse train generated from a single carbon fiber field emission cathode using the same technique.

  11. Ris Energy Report 5 Global drivers for transformation of energy systems 3 Global drivers for transformation of energy

    E-Print Network [OSTI]

    of greenhouse gases has brought a new political rationale for the development of more climate-friendly energy in the global energy market of rapidly-expanding national economies, notably China and India. TogetherRisø Energy Report 5 Global drivers for transformation of energy systems 3 Global drivers

  12. Driver performance data acquisition system for ergonomics research

    SciTech Connect (OSTI)

    Carter, R.J.; Goodman, M.J.

    1994-12-31

    A portable ergonomics data acquisition system consisting of state-of-the-art hardware being designed is described here. It will be employed to record driver, vehicle, and environment parameter data from a wide range of vehicles and trucks. The system will be unobtrusive to the driver and inconspicuous to the outside world. It will have three modes of data gathering and provide for extended periods of data collection. Modularity, flexibility, and cost will be key drivers in the development effort. The ergonomics data acquisition system project is being conducted in two phases--a feasibility study and a development, construction, and validation phase.

  13. Accident Analysis and Prevention 42 (2010) 364371 Contents lists available at ScienceDirect

    E-Print Network [OSTI]

    Boggess, May M.

    2010-01-01

    number of studies reported age-specific accident rates for heavy vehicles for the spec- trum of driver' shaped curve indicates a higher risk of accident involvement for both younger and older drivers. More

  14. Drivers of the US CO2 emissions 1997-2013

    E-Print Network [OSTI]

    2015-01-01

    drivers of regional carbon dioxide emissions for China. J.D. & Rose, A. Carbon dioxide emissions in the U.S. economy.Analysis of Carbon Dioxide Emission Changes in Germany -

  15. A novel active heads-up display for driver assistance.

    E-Print Network [OSTI]

    Doshi, Anup; Cheng, Shinko Yuanhsien; Trivedi, Mohan Manubhai

    2009-01-01

    and P. Green, “The effect of HUD warning location on driverComparison of head-up display (HUD) vs. head-down display (also use heads-up displays (HUDs) to convey information to

  16. An affective intelligent driving agent: driver's trajectory and activities prediction.

    E-Print Network [OSTI]

    Ratti, Carlo

    The traditional relationship between the car, driver, and city can be described as waypoint navigation with additional traffic and maintenance information. The car can receive and store waypoint information, find the ...

  17. Visual Attention and Driver Performance at Horizontal Curves 

    E-Print Network [OSTI]

    Brimley, Bradford K.

    2014-12-02

    at any location and on any facility. Traffic control devices (TCDs) can be installed at curves to provide drivers the information necessary for safe navigation. The research in this dissertation examines the theory that TCDs at curves are not only...

  18. FlightCrew Browser : a safe browser for drivers

    E-Print Network [OSTI]

    López-Pineda, Andrés Humberto

    2013-01-01

    Drivers have information needs they want to solve while driving, but current mobile browser interfaces can bring forth safety issues when users browse the web even though their attention is required elsewhere, as it is ...

  19. University of Wisconsin-Milwaukee Employment & Training Institute Driver's License Issues

    E-Print Network [OSTI]

    Saldin, Dilano

    University of Wisconsin-Milwaukee Employment & Training Institute Driver's License Issues-Milwaukee Employment & Training Institute Driver's license obstacles 1. Lack of driver's education in the high schools of unlicensed driving 4. Court-ordered 2-year driver's license suspensions as a tool to collect municipal fines

  20. Science Drivers and Technical Challenges for Advanced Magnetic Resonance

    SciTech Connect (OSTI)

    Mueller, Karl T.; Pruski, Marek; Washton, Nancy M.; Lipton, Andrew S.

    2013-03-07

    This report recaps the "Science Drivers and Technical Challenges for Advanced Magnetic Resonance" workshop, held in late 2011. This exploratory workshop's goal was to discuss and address challenges for the next generation of magnetic resonance experimentation. During the workshop, participants from throughout the world outlined the science drivers and instrumentation demands for high-field dynamic nuclear polarization (DNP) and associated magnetic resonance techniques, discussed barriers to their advancement, and deliberated the path forward for significant and impactful advances in the field.

  1. Look-ahead driver feedback and powertrain management

    SciTech Connect (OSTI)

    Verma, Rajeev

    2014-12-31

    Commercial medium and heavy vehicles, though only a small portion of total vehicle population, play a significant role in energy consumption. In 2012, these vehicles accounted for about 5775.5 trillion btu of energy consumption and 408.8 million tons of CO2 emissions annually, which is a quarter of the total energy burden of highway transportation in the United States [1]. This number is expected to surpass passenger car fuel use within the next few decades. In the meantime, most commercial vehicle fleets are running at a very low profit margin. It is a well known fact that fuel economy can vary significantly between drivers, even when they operate the same vehicle on the same route. According to the US Environmental Protection Agency (EPA) and Natural Resource Canada (NRCan), there is up to 35% fuel economy difference between drivers within the same commercial fleet [2] [3], [4]. Similar results were obtained from a Field Operation Test conducted by Eaton Corporation [5]. During this test as much as 30% fuel economy difference was observed among pick-up-and-delivery drivers and 11% difference was observed among line-haul drivers. The driver variability can be attributed to the fact that different drivers react differently to driving conditions such as road grade, traffic, speed limits, etc. For instance, analysis of over 600k miles of naturalistic heavy duty truck driving data [5] indicates that an experienced driver anticipates a downhill and eases up on the throttle to save fuel while an inexperienced driver lacks this judgment.

  2. Game Theoretic Modelling of a Human Driver’s Steering Interaction with Vehicle Active Steering Collision Avoidance System

    E-Print Network [OSTI]

    Na, Xiaoxiang; Cole, David J.

    2014-11-10

    deeper insights into physiological and cognitive behaviours of human drivers so that optimization of present or future driver-automation interfaces, e.g. continuous sharing control [8] becomes a possibility. However, little attention has yet been paid... Model Predictive Control (MPC) and the Linear Quadratic (LQ) dynamic optimization approaches. A. Distributed MPC The idea of distributed MPC was presented in [26] as a practical approach to industrial process control of large-scale systems...

  3. Index of /~lipman/papers-older/Other professional publications

    E-Print Network [OSTI]

    Index of /~lipman/papers-older/Other professional publications. [ICO], Name · Last modified · Size · Description. [DIR], Parent Directory, -. [ ], [1980] Review of ...

  4. Analyzing Vehicle Fuel Saving Opportunities through Intelligent Driver Feedback

    SciTech Connect (OSTI)

    Gonder, J.; Earleywine, M.; Sparks, W.

    2012-06-01

    Driving style changes, e.g., improving driver efficiency and motivating driver behavior changes, could deliver significant petroleum savings. This project examines eliminating stop-and-go driving and unnecessary idling, and also adjusting acceleration rates and cruising speeds to ideal levels to quantify fuel savings. Such extreme adjustments can result in dramatic fuel savings of over 30%, but would in reality only be achievable through automated control of vehicles and traffic flow. In real-world driving, efficient driving behaviors could reduce fuel use by 20% on aggressively driven cycles and by 5-10% on more moderately driven trips. A literature survey was conducted of driver behavior influences, and pertinent factors from on-road experiments with different driving styles were observed. This effort highlighted important driver influences such as surrounding vehicle behavior, anxiety over trying to get somewhere quickly, and the power/torque available from the vehicle. Existing feedback approaches often deliver efficiency information and instruction. Three recommendations for maximizing fuel savings from potential drive cycle improvement are: (1) leveraging applications with enhanced incentives, (2) using an approach that is easy and widely deployable to motivate drivers, and (3) utilizing connected vehicle and automation technologies to achieve large and widespread efficiency improvements.

  5. Analytics For Distracted Driver Behavior Modeling in Dilemma Zone

    SciTech Connect (OSTI)

    Li, Jan-Mou [ORNL] [ORNL; Malikopoulos, Andreas [ORNL] [ORNL; Thakur, Gautam [ORNL] [ORNL; Vatsavai, Raju [ORNL] [ORNL

    2014-01-01

    In this paper, we present the results obtained and insights gained through the analysis of TRB contest data. We used exploratory analysis, regression, and clustering models for gaining insights into the driver behavior in a dilemma zone while driving under distraction. While simple exploratory analysis showed the distinguishing driver behavior patterns among different popu- lation groups in the dilemma zone, regression analysis showed statically signification relationships between groups of variables. In addition to analyzing the contest data, we have also looked into the possible impact of distracted driving on the fuel economy.

  6. Cars and Drivers in the New Suburbs: Linking Access to Travel in Neotraditional Planning

    E-Print Network [OSTI]

    Crane, Randall

    1994-01-01

    Neotradltlonal TownPlanmng. Cars, Pedestmans, and Transit,Cars and Drivers in the NewSuburbs: Linking Access to Travelspccxfica~on, or mguIahon Cars and Drivers in the New

  7. Driver mental workload requirements on horizontal curves based on occluded vision test measurements 

    E-Print Network [OSTI]

    Shafer, Mark Anthony

    1994-01-01

    This thesis documents an evaluation of driver mental workload requirements on horizontal curves based on occluded vision test measurements. Driver workload is an important concept in the design of highway systems. A ...

  8. Final Report on the Fuel Saving Effectiveness of Various Driver Feedback Approaches

    SciTech Connect (OSTI)

    Gonder, J.; Earleywine, M.; Sparks, W.

    2011-03-01

    This final report quantifies the fuel-savings opportunities from specific driving behavior changes, identifies factors that influence drivers' receptiveness to adopting fuel-saving behaviors, and assesses various driver feedback approaches.

  9. Drivers and Barriers for Implementing Sustainable Development in Higher Education

    E-Print Network [OSTI]

    Svenningsson, Josef

    #12;Drivers and Barriers for Implementing Sustainable Development in Higher Education Göteborg for Sustainable Development through Higher Education. The authors are responsible for the choice and presentation.unesco.org/education/desd Education for Sustainable Development in Action Technical Paper N° 3 - 2006 Cover design: Helmut Langer (ED

  10. Stochastic and deterministic drivers of spatial and temporal turnover in

    E-Print Network [OSTI]

    Kraft, Nathan

    and Sustainability, and Department of Zoology, Miami University, Oxford, USA, 5 New Zealand Institute for Advanced filtering). While numerous studies have examined the relation- ship between turnover and individual drivers effects were removed, but relation- ships with primary productivity and habitat heterogeneity remained

  11. DYNAMIC DATABASE INTEGRATION IN A JDBC DRIVER Terrence Mason

    E-Print Network [OSTI]

    Lawrence, Ramon

    -lawrence@uiowa.edu Keywords: integration, database, schema, metadata, annotation, evolution, dynamic, JDBC, conceptualDYNAMIC DATABASE INTEGRATION IN A JDBC DRIVER Terrence Mason Iowa Database and Emerging Iowa Database and Emerging Applications Laboratory, Computer Science University of Iowa Email: ramon

  12. Fluctuations in Alertness and Sustained Attention: Predicting Driver Performance

    E-Print Network [OSTI]

    Salvucci, Dario D.

    Fluctuations in Alertness and Sustained Attention: Predicting Driver Performance Glenn Gunzelmann an existing account of the effect of sleep loss and circadian rhythms on sustained attention performance to predict performance impairments in complex task domains like driving is limited by a gap in our

  13. Energy for 500 million Homes: Drivers and Outlook for

    E-Print Network [OSTI]

    -up analysis of residential building energy consumption in China using data from a wide variety of sourcesLBNL-2417E Energy for 500 million Homes: Drivers and Outlook for Residential Energy Consumption and Outlook for Residential Energy Consumption in China Nan Zhou*, Michael A. McNeil, Mark Levine Keywords

  14. SECTION 9-DRIVER SAFETY PROGRAM AND VEHICLE OPERATION/ AND MAINTENANCE

    E-Print Network [OSTI]

    Selmic, Sandra

    SECTION 9- DRIVER SAFETY PROGRAM AND VEHICLE OPERATION/ AND MAINTENANCE INTRODUCTION Driving, driving statistically exposes you to the single greatest degree of risk in your everyday life. The driving in a vehicular accident while conducting State business. · Make recommendations on how to operate a vehicle

  15. Integrating Concurrency Control and Energy Management in Device Drivers

    E-Print Network [OSTI]

    Maróti, Miklós

    Integrating Concurrency Control and Energy Management in Device Drivers Kevin Klues , Vlado@cs.berkeley.edu dgay@intel-research.net Abstract Energy management is a critical concern in wireless sensornets. De- spite its importance, sensor network operating systems today pro- vide minimal energy management support

  16. Project: Driver and controller for a thermoelectric cooler

    E-Print Network [OSTI]

    Project: Driver and controller for a thermoelectric cooler Supervisor: Prof. Sam Ben-Yaakov Year solutions. Based on one of the three thermoelectric phenomena ­ the Peltier effect ­ bi-directional control is achieved. The TEC (which is a Thermoelectric Cooler) uses this effect. The direction of the current through

  17. A REVIEW AND EVALUATION OF EMERGING DRIVER FATIGUE DETECTION MEASURES AND TECHNOLOGIES

    E-Print Network [OSTI]

    -to-perform and fitness-for-duty screeners; mathematical models/algorithms; vehicle-based driver performance measurements

  18. Driver/Pedestrian Understanding and Behavior at Marked and Unmarked Crosswalks

    E-Print Network [OSTI]

    Mitman, Meghan F.; Ragland, David R

    2008-01-01

    45 PEDESTRIAN CRASH PATTERNS IN45 PEDESTRIAN AND DRIVER KNOWLEDGE OF CROSSWALK47 COUNTERMEASURES TO INCREASE PEDESTRIAN SAFETY IN

  19. Two-Stage Power Conversion Architecture for an LED Driver Circuit

    E-Print Network [OSTI]

    Perreault, Dave

    Two-Stage Power Conversion Architecture for an LED Driver Circuit Seungbum Lim, John Ranson, David with 0.93 power factor at 8.4 W average power. I. INTRODUCTION LED lighting promises unprecedented efficiency, and high-power-factor LED drivers [1]. A survey of commercial LED drivers illustrates this

  20. University of Wisconsin-Milwaukee Employment & Training Institute 1 Drivers License

    E-Print Network [OSTI]

    Saldin, Dilano

    University of Wisconsin-Milwaukee Employment & Training Institute 1 Drivers License Status Report for the Center on Driver's License Recovery & Employability June 13, 2012 by Lois Quinn and John Pawasarat residents in the state DOT files, including: · drivers with a current license as of January 2012 · plus

  1. Laser-seeded modulation instability in a proton driver plasma wakefield accelerator

    SciTech Connect (OSTI)

    Siemon, Carl; Khudik, Vladimir; Austin Yi, S.; Shvets, Gennady; Pukhov, Alexander

    2013-10-15

    A new method for initiating the modulation instability (MI) of a proton beam in a proton driver plasma wakefield accelerator using a short laser pulse preceding the beam is presented. A diffracting laser pulse is used to produce a plasma wave that provides a seeding modulation of the proton bunch with the period equal to that of the plasma wave. Using the envelope description of the proton beam, this method of seeding the MI is analytically compared with the earlier suggested seeding technique that involves an abrupt truncation of the proton bunch. The full kinetic simulation of a realistic proton bunch is used to validate the analytic results. It is further used to demonstrate that a plasma density ramp placed in the early stages of the laser-seeded MI leads to its stabilization, resulting in sustained accelerating electric fields (of order several hundred MV/m) over long propagation distances (?100–1000 m)

  2. Older adult consumers of Texas public mental health services: 

    E-Print Network [OSTI]

    Karlin, Bradley Eric

    2002-01-01

    at disproportionately low rates. Although recent changes in public policies and perceptions portend improved access to mental health services, we cannot assume that older adults are finding their way into the therapy room and receiving treatment. The present study...

  3. Health Status and Health Literacy in Older Adults 

    E-Print Network [OSTI]

    Fulton, Daphne Saxon

    2014-08-04

    This study aimed to examine the relationship between health literacy and the health status of older adults. The first section of the study consisted of a comprehensive literature review of prior research regarding cognitive, health, and behavioral...

  4. 59136 Federal Register / Vol. 75, No. 186 / Monday, September 27, 2010 / Rules and Regulations (c) Certain farm vehicle drivers. The

    E-Print Network [OSTI]

    ) Certain farm vehicle drivers. The rules in this part except for § 391.15(e) do not apply to a farm vehicle driver except a farm vehicle driver who drives an articulated (combination) commercial motor vehicle, as defined in § 390.5. For limited exemptions for farm vehicle drivers of articulated commercial motor

  5. Utility Integrated Resource Planning: An Emerging Driver of New Renewable Generation in the Western United States

    E-Print Network [OSTI]

    Bolinger, Mark; Wiser, Ryan

    2005-01-01

    greater role in future utility planning efforts. Bolinger,Utility Integrated Resource Planning: An Emerging Driver ofyears: utility integrated resource planning (IRP). Common in

  6. Philips Light Sources & Electronics is Developing an Efficient, Smaller, Cost-Effective Family of LED Drivers

    Broader source: Energy.gov [DOE]

    With the help of DOE funding, Philips Light Sources & Electronics is developing a new family of LED drivers that are more efficient and cost-effective as well as smaller in size than currently available drivers. The new drivers are switch-mode power supplies that are similar to today's drivers, but with an improved design. In addition, they have a different topology—boost plus LLC—for wattages of 40W and above, but they retain the commonly used flyback topology at lower wattages.

  7. Driver/Pedestrian Understanding and Behavior at Marked and Unmarked Crosswalks

    E-Print Network [OSTI]

    Ragland, David R; Mitman, Meghan Fehlig

    2007-01-01

    July 1, 2007 DRIVER/PEDESTRIAN UNDERSTANDING AND BEHAVIOR AT9922 BERKELEY MANIFESTO ON PEDESTRIAN CROSSINGS MAY 11, 2007for safe and convenient pedestrian travel and to embrace

  8. Blue oak seedlings may be older than they look

    E-Print Network [OSTI]

    Blue oak seedlings may be older than they look Ralph L. Phillips u Neil K. McDougald o Richard B. Standiford William E.Frost A 4-year study indicates that na- tive blue oak seedlings are prob- ably much the year of above- average rainfall. Blue oak (Quercusdouglasii)trees are a valuable economic and aesthetic

  9. Strategies for finding government information by older people

    E-Print Network [OSTI]

    Curzon, Paul

    -government agenda, suggested it was inevitable that online information sources would become the primary means for achieving an individual's personal aims of using the internet over other information sources. We doStrategies for finding government information by older people Paul Curzon, Suzette Keith, Gill

  10. Community-Dwelling Older Adults: Services, Cost, and Changes 

    E-Print Network [OSTI]

    Lin, Szu-Hsuan

    2015-07-21

    With every generation living longer than the last, and the baby boomer generation (one of the largest generations in US history) starting to reach age 65, the demographics of the United States (U.S.) is aging. Older adults are one of the fastest...

  11. Marine Iguanas Older Than Their Islands Jeff Mitton

    E-Print Network [OSTI]

    Mitton, Jeffry B.

    Marine Iguanas Older Than Their Islands Jeff Mitton Natural Selections (Appeared in the Boulder endemic species remain, three land iguanas and the only marine iguana in the world. The marine iguana by a variety of green and red algae. Marine iguanas rely solely on marine algae but they are not restricted

  12. Policy on Programs Involving Minors Policy on Programs Involving

    E-Print Network [OSTI]

    Sridhar, Srinivas

    Policy on Programs Involving Minors 6/4/2014 Policy on Programs Involving Minors I. Purpose in University-sponsored activities that take place off campus. This policy applies to University or facilities that are operated or sponsored by third parties. This policy provides program registration

  13. Dynamical 3-Space: Supernovae and the Hubble Expansion - Older Universe and End of Dark Energy

    E-Print Network [OSTI]

    Reginald T Cahill

    2007-06-05

    We apply the new dynamics of 3-space to cosmology by deriving a Hubble expansion solution. This dynamics involves two constants; G and alpha - the fine structure constant. This solution gives an excellent parameter-free fit to the recent supernova and gamma-ray burst data without the need for `dark energy' or `dark matter'. The data and theory together imply an older age for the universe of some 14.7Gyrs. Various problems such as fine tuning, the event horizon problem etc are now resolved. A brief review discusses the origin of the 3-space dynamics and how that dynamics explained the bore hole anomaly, spiral galaxy flat rotation speeds, the masses of black holes in spherical galaxies, gravitational light bending and lensing, all without invoking `dark matter' or `dark energy'. These developments imply that a new understanding of the universe is now available.

  14. UWB multi-burst transmit driver for averaging receivers

    DOE Patents [OSTI]

    Dallum, Gregory E

    2012-11-20

    A multi-burst transmitter for ultra-wideband (UWB) communication systems generates a sequence of precisely spaced RF bursts from a single trigger event. There are two oscillators in the transmitter circuit, a gated burst rate oscillator and a gated RF burst or RF power output oscillator. The burst rate oscillator produces a relatively low frequency, i.e., MHz, square wave output for a selected transmit cycle, and drives the RF burst oscillator, which produces RF bursts of much higher frequency, i.e., GHz, during the transmit cycle. The frequency of the burst rate oscillator sets the spacing of the RF burst packets. The first oscillator output passes through a bias driver to the second oscillator. The bias driver conditions, e.g., level shifts, the signal from the first oscillator for input into the second oscillator, and also controls the length of each RF burst. A trigger pulse actuates a timing circuit, formed of a flip-flop and associated reset time delay circuit, that controls the operation of the first oscillator, i.e., how long it oscillates (which defines the transmit cycle).

  15. Fact #845 November 3, 2014 From 1970 to 2013 the Share of Older...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    to 2013 the Share of Older Vehicles in Operation has Increased In 1970 only 3% of the cars in operation were 15 years old or older. With cars lasting much longer today, 19% of...

  16. Internet Technology and Social Support: Are They Beneficial for Overweight Older Adolescents? 

    E-Print Network [OSTI]

    Olson, Wendy Ann

    2011-10-21

    , the Model of Influence of Social Support on Health Behavior (MISSHRB), in a group of older adolescents; 2) To determine the feasibility and clinical utility of an internet intervention for social support for overweight older adolescents, and 3) To examine...

  17. RESEARCH OR TEACHING INVOLVING ANIMALS

    E-Print Network [OSTI]

    Victoria, University of

    Page 1 RESEARCH OR TEACHING INVOLVING ANIMALS University Policy No: RH8110 Classification: Research Approving Authority: Vice-President Research Effective date: June, 2014 Supersedes: December, 2010 Last for Conducting Research or Teaching Involving Animals Animal Care Committee Terms of Reference PURPOSE 1

  18. PREVENTING LOSS OF INDEPENDENCE THROUGH EXERCISE (PLIE) FOR OLDER ADULTS WITH DEMENTIA

    E-Print Network [OSTI]

    Barnes, DE; Chesney, MA; Yaffe, K; Flores, C; Wu, E; Mehling, WE

    2012-01-01

    2000) The effects of tai chi chuan relaxation and exerciseChi instructor (Founder, Tai Chi Chuan Program, Older Adults

  19. The Influence of Self-Perceptions of Aging on Older Adults' Cognition and Behavior 

    E-Print Network [OSTI]

    Hughes, Matthew Lane

    2014-07-29

    people falsely believe that a majority of older adults are impoverished, irritable, and lonely. Additionally, they believe that a disproportional number of older adults live in nursing homes (people believe that 10% of older adults live in nursing... THE INFLUENCE OF SELF-PERCEPTIONS OF AGING ON OLDER ADULTS’ COGNITION AND BEHAVIOR A Dissertation by MATTHEW LANE HUGHES Submitted to the Office of Graduate and Professional Studies of Texas A&M University in partial fulfillment of the requirements...

  20. Nash Equilibria for a Model of Traffic Flow with Several Groups of Drivers

    E-Print Network [OSTI]

    Nash Equilibria for a Model of Traffic Flow with Several Groups of Drivers Alberto Bressan and Ke population sizes 1, . . . , n, we prove the existence of a Nash equilibrium solution, where no driver can, and a characterization of this Nash equilibrium solution, are also discussed. 1 Introduction Consider a model of traffic

  1. Nash Equilibria for a Model of Traffic Flow with Several Groups of Drivers

    E-Print Network [OSTI]

    Bressan, Alberto

    Nash Equilibria for a Model of Traffic Flow with Several Groups of Drivers Alberto Bressan and Ke population sizes 1, . . . , n, we prove the existence of a Nash equilibrium solution, where no driver can, and a characterization of this Nash equilibrium solution, are also discussed. Key words: Scalar conservation law

  2. 1 Drivers of the projected changes to the Pacific Ocean 2 equatorial circulation

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    1 Drivers of the projected changes to the Pacific Ocean 2 equatorial circulation 3 A. Sen Gupta,1 A), 29 Drivers of the projected changes to the Pacific Ocean equatorial 30 circulation, Geophys. Res. Lett., 39, LXXXXX, doi:10.1029/ 31 2012GL051447. 32 1. Introduction 33 [2] The equatorial Pacific Ocean

  3. AABBSSTTRRAACCTT MA, RUIQI. The Effect of In-Vehicle Automation and Reliability on Driver Situation

    E-Print Network [OSTI]

    Kaber, David B.

    AABBSSTTRRAACCTT MA, RUIQI. The Effect of In-Vehicle Automation and Reliability on Driver Situation by automation and in- vehicle device use. Specifically, this study investigated the implications of adaptive; investigate the effect of varying reliability of in-vehicle automation (navigation aids) on driver SA

  4. ESPM 131 Using microbes to understand effects S06 and drivers of species diversity

    E-Print Network [OSTI]

    Bruns, Tom

    ESPM 131 Using microbes to understand effects S06 and drivers of species diversity Microbial. Perceived disadvantages and counterpoints: too simple, too artificial microbes are fundamentally different;ESPM 131 Using microbes to understand effects S06 and drivers of species diversity Species richness

  5. Predicting the Effects of In-Car Interfaces on Driver Behavior using a Cognitive Architecture

    E-Print Network [OSTI]

    Salvucci, Dario D.

    Predicting the Effects of In-Car Interfaces on Driver Behavior using a Cognitive Architecture Dario 9669 dario@cbr.com ABSTRACT When designing and evaluating "in-car" user interfaces for drivers describes a novel approach to predicting effects of in-car interfaces by modeling behavior in a cognitive

  6. Driver Attitudes and Choices: Speed Limits, Seat Belt Use, and Drinking-and-Driving

    E-Print Network [OSTI]

    Kockelman, Kara M.

    Driver attitudes; Driver behavior; Speeding; Motor Vehicle Occupant Safety Surveys (MVOSS) #12;- 2 Board, January 2004 Abstract A better understanding of attitudes and behavioral principles underlying driving behavior and traffic safety issues can contribute to design and policy solutions, such as, speed

  7. Integrated Circuit Implementation for a GaN HFETs Driver Circuit

    E-Print Network [OSTI]

    Bakos, Jason D.

    @engr.sc.edu Abstract- The paper presents the design of an integrated circuit (IC) for a 10MHz low power-loss driver exploit the advantages of GaN devices, such as superior switching speed and operation in high-power the authors focus on the design of the IC and present preliminary results and considerations. The driver

  8. An Electrolytic-Free Offline LED Driver with a Ceramic-Capacitor-Based Compact SSC Energy

    E-Print Network [OSTI]

    Perreault, Dave

    An Electrolytic-Free Offline LED Driver with a Ceramic-Capacitor-Based Compact SSC Energy Buffer of a compact ceramic-capacitor-based stacked switched capacitor (SSC) energy buffer for a single-stage offline precharge circuit. The prototype LED driver presented here uses a ceramic-capacitor-based SSC energy buffer

  9. Can You Teach an Old Dog New Tricks? How Older Adults Perceive Embodied Agents

    E-Print Network [OSTI]

    Theune, Mariët

    Can You Teach an Old Dog New Tricks? How Older Adults Perceive Embodied Agents Mariët Theune In this experiment we investigate how older adults perceive an embodied agent as compared to younger people in the context of an information giving task. Our results show that older adults found the agent less friendly

  10. Internet use and non-use: views of older users ANNE MORRIS*, JOY GOODMAN

    E-Print Network [OSTI]

    Goodman, Joy

    1 Internet use and non-use: views of older users ANNE MORRIS*, JOY GOODMAN + AND HELENA BRADING: older people elderly Internet digital divide technology Abstract: This paper reports the results of two connected surveys of computer and Internet use among the older population in the UK. 120 questionnaires

  11. Laddie: The Language for Automated Device Drivers (Ver 1) Bucknell Computer Science Technical Report #08-2

    E-Print Network [OSTI]

    Wittie, Lea

    Report #08-2 Lea Wittie March 12, 2008 Abstract Device drivers, which make up a large portion. Rebooting can mean data loss; a CD-RW writing a CD, network card sending packets. The driver could also read

  12. Low impedance z-pinch drivers without post-hole convolute current adders.

    SciTech Connect (OSTI)

    Savage, Mark Edward; Seidel, David Bruce; Mendel, Clifford Will, Jr.

    2009-09-01

    Present-day pulsed-power systems operating in the terawatt regime typically use post-hole convolute current adders to operate at sufficiently low impedance. These adders necessarily involve magnetic nulls that connect the positive and negative electrodes. The resultant loss of magnetic insulation results in electron losses in the vicinity of the nulls that can severely limit the efficiency of the delivery of the system's energy to a load. In this report, we describe an alternate transformer-based approach to obtaining low impedance. The transformer consists of coils whose windings are in parallel rather than in series, and does not suffer from the presence of magnetic nulls. By varying the pitch of the coils windings, the current multiplication ratio can be varied, leading to a more versatile driver. The coupling efficiency of the transformer, its behavior in the presence of electron flow, and its mechanical strength are issues that need to be addressed to evaluate the potential of transformer-based current multiplication as a viable alternative to conventional current adder technology.

  13. Study of CSR Effects in the Jefferson Laboratory FEL Driver

    SciTech Connect (OSTI)

    Hall, C. C.; Biedron, S.; Burleson, Theodore A.; Milton, Stephen V.; Morin, Auralee L.; Benson, Stephen V.; Douglas, David R.; Evtushenko, Pavel E.; Hannon, Fay E.; Li, Rui; Tennant, Christopher D.; Zhang, Shukui; Carlsten, Bruce E.; Lewellen, John W.

    2013-08-01

    In a recent experiment conducted on the Jefferson Laboratory IR FEL driver the effects of Coherent Synchrotron Radiation (CSR) on beam quality were studied. The primary goal of this work was to explore CSR output and effect on the beam with variation of the bunch compression in the IR chicane. This experiment also provides a valuable opportunity to benchmark existing CSR models in a system that may not be fully represented by a 1-D CSR model. Here we present results from this experiment and compare to initial simulations of CSR in the magnetic compression chicane of the machine. Finally, we touch upon the possibility for CSR induced microbunching gain in the magnetic compression chicane, and show that parameters in the machine are such that it should be thoroughly damped.

  14. The effects of practicing speech accommodations to older adults

    E-Print Network [OSTI]

    Kemper, Susan; Othick, Meghan; Gerhing, Hope; Gubarchuk, Julia; Billington, Catherine

    1998-01-01

    Applied Psycholinguistics 19 (1998), 175-192 Printed in the United States of America The effects of practicing speech accommodations to older adults SUSAN KEMPER, MEGHAN OTHICK, HOPE GERHING, JULIA GUBARCHUK, and CATHERINE BILLINGTON University... for the segment durations (Cronbach's alpha >.80, for all measures). Word and utterance counts, type/ token ratios, and mean lengths of utterance were computed by the SALT (Chap- man & Miller, 1984) computer program, which was used to facilitate all anal- yses...

  15. Some Ramsey Problems Involving Triangles -

    E-Print Network [OSTI]

    Radziszowski, Stanislaw P.

    Some Ramsey Problems Involving Triangles - Computational Approach Stanislaw Pawel Radziszowski Department of Computer Science Rochester Institute of Technology, NY ramsey@dimacs, 28 may 2009 1/40 #12;Outline - Triangles Everywhere or avoiding K3 in some/most colors 1 Ramsey Numbers - Two Colors Some known

  16. Radiological science involves technologists use

    E-Print Network [OSTI]

    Sibille, Etienne

    English Composition II Mathematics MATH 0110 Fundamentals of Mathematics THE HUMAN EXPERIENCE Students new Clinical Experience Radiographic Procedures II Radiation Protection II Radiographic Film ProcessingRadiological science involves technologists use X-rays to see the inside of the human body. Health

  17. Dynamic analysis of policy drivers for bioenergy commodity markets

    SciTech Connect (OSTI)

    Robert F. Jeffers; Jacob J. Jacobson; Erin M. Searcy

    2001-01-01

    Biomass is increasingly being considered as a feedstock to provide a clean and renewable source of energy in the form of both liquid fuels and electric power. In the United States, the biofuels and biopower industries are regulated by different policies and have different drivers which impact the maximum price the industries are willing to pay for biomass. This article describes a dynamic computer simulation model that analyzes future behavior of bioenergy feedstock markets given policy and technical options. The model simulates the long-term dynamics of these markets by treating advanced biomass feedstocks as a commodity and projecting the total demand of each industry as well as the market price over time. The model is used for an analysis of the United States bioenergy feedstock market that projects supply, demand, and market price given three independent buyers: domestic biopower, domestic biofuels, and foreign exports. With base-case assumptions, the biofuels industry is able to dominate the market and meet the federal Renewable Fuel Standard (RFS) targets for advanced biofuels. Further analyses suggest that United States bioenergy studies should include estimates of export demand in their projections, and that GHG-limiting policy would partially shield both industries from exporter dominance.

  18. Vehicle Technologies Office Merit Review 2014: Look-Ahead Driver Feedback and Powertrain Management

    Broader source: Energy.gov [DOE]

    Presentation given by Eaton at 2014 DOE Hydrogen and Fuel Cells Program and Vehicle Technologies Office Annual Merit Review and Peer Evaluation Meeting about look-ahead driver feedback and...

  19. Emergency vehicle driver training by Texas municipal police departments: a descriptive study 

    E-Print Network [OSTI]

    Westmoreland, Robert Lawrence

    1994-01-01

    police departments with 26 or more sworn police officers were mailed questionnaires that were to be completed and returned to the researcher. The questionnaire requested information on the current emergency driver training program of each agency. Results...

  20. Two-stage power conversion architecture for an LED driver circuit

    E-Print Network [OSTI]

    Lim, Seungbum

    This paper presents a merged-two-stage circuit topology suitable for efficient LED drivers operating from either wide-range dc input voltage or ac line voltage. This two-stage topology is based on a soft-charged ...

  1. State of Wisconsin Fleet Driver and Management Policies and Procedures Manual 1 State of Wisconsin

    E-Print Network [OSTI]

    Meyers, Stephen R.

    .30. Lease and Rental Rates 30 2.31. Citizen Driver Complaints 30 Appendix Directory 30 #12;State confusion between previous versions, (3) increase employee and public understanding of the overall state

  2. Using NASA-Task Load Index to Assess Drivers' Workload on Freeway Guide Sign Structures

    E-Print Network [OSTI]

    Using NASA-Task Load Index to Assess Drivers' Workload on Freeway Guide Sign Structures Fengxiang are carefully analyzed using the NASA-Task Load Index. With the statistical analyses of questionnaires

  3. FALLOW MANAGEMENT PRACTICES IN GUATEMALA'S WESTERN HIGHLANDS: SOCIAL DRIVERS AND BIOPHYSICAL IMPACTSy

    E-Print Network [OSTI]

    FALLOW MANAGEMENT PRACTICES IN GUATEMALA'S WESTERN HIGHLANDS: SOCIAL DRIVERS AND BIOPHYSICAL practices in the Western Highlands of Guatemala based on interdisciplinary data collected using fertility; Buddleia skutchii; Baccharis vaccinioides; Andisol; Guatemala INTRODUCTION At any given time

  4. Temperature as a driver for the expansion of the microalga Gonyostomum semen in Swedish lakes

    E-Print Network [OSTI]

    Temperature as a driver for the expansion of the microalga Gonyostomum semen in Swedish lakes Karin is an example of invasive harmful microalgae (Neilan et al., 2003). Another presumably invasive species

  5. Personality fit in nascar: does driver-sponsor congruence influence sponsorship effectiveness outcomes? 

    E-Print Network [OSTI]

    Dees, Windy Lynn

    2009-05-15

    The purpose of this study was to determine if personality fit between NASCAR drivers and their major sponsors affects the sponsorship outcomes of consumer attitudes toward the sponsor, attitudes toward the brand, and ...

  6. Fourth Annual Ethical Leadership Conference Panel Drivers, Challenges, and Strategies for Future of Corporate

    E-Print Network [OSTI]

    Lin, Xiaodong

    Fourth Annual Ethical Leadership Conference Panel Drivers, Challenges, and Strategies for Future, Academy of Management Review, Academy of Management Perspectives, Business & Society, Long Range Planning Social Responsibility for Hess Corporation, a global integrated energy company based in New York City

  7. Marine metagenomic infrastructure services as driver for research and industrial innovation

    E-Print Network [OSTI]

    Bongo, Lars Ailo

    Marine metagenomic infrastructure services as driver for research and industrial innovation Lars-EBI) · Participants: ­ Calouste Gulbenkian Foundation (Portugal) ­ CCMAR ­ Center for Marine Sciences (Portugal;Marine Metagenomics · Marine genomics and metagenomics are rapidly expanding · Need customized data

  8. Business-to-business electronic marketplaces: membership and use drivers 

    E-Print Network [OSTI]

    Koch, Hope Arlene

    2004-09-30

    and low use organizations, buying and selling organizations, and a nonparticipant organization. The interview data was analyzed using line-by-line analysis from grounded theory. The analysis involved assimilating the unique stories of each manager...

  9. EXTENDING THE USEFUL LIFE OF OLDER MASS SPECTROMETERS

    SciTech Connect (OSTI)

    Johnson, S.; Cordaro, J.; Holland, M.; Jones, V.

    2010-06-17

    Thermal ionization and gas mass spectrometers are widely used across the Department of Energy (DOE) Complex and contractor laboratories. These instruments support critical missions, where high reliability and low measurement uncertainty are essential. A growing number of these mass spectrometers are significantly older than their original design life. The reality is that manufacturers have declared many of the instrument models obsolete, with direct replacement parts and service no longer available. Some of these obsolete models do not have a next generation, commercially available replacement. Today's budget conscious economy demands for the use of creative funds management. Therefore, the ability to refurbish (or upgrade) these valuable analytical tools and extending their useful life is a cost effective option. The Savannah River Site (SRS) has the proven expertise to breathe new life into older mass spectrometers, at a significant cost savings compared to the purchase and installation of new instruments. A twenty-seven year old Finnigan MAT-261{trademark} Thermal Ionization Mass Spectrometer (TIMS), located at the SRS F/H Area Production Support Laboratory, has been successfully refurbished. Engineers from the Savannah River National Laboratory (SRNL) fabricated and installed the new electronics. These engineers also provide continued instrument maintenance services. With electronic component drawings being DOE Property, other DOE Complex laboratories have the option to extend the life of their aged Mass Spectrometers.

  10. Serum 25-OH vitamin D levels and risk of developing prostate cancer in older men

    E-Print Network [OSTI]

    2010-01-01

    older men Christine M. Barnett • Carrie M. Nielson • JackieD Á Prostate cancer C. M. Barnett Á T. M. Beer (&) Division

  11. Testing Enhances Subsequent Learning in Older but not in Younger Elementary School Children

    E-Print Network [OSTI]

    Schubart, Christoph

    Testing Enhances Subsequent Learning in Older but not in Younger Elementary School Children Alp-345-55-24353 Running Head: Test-Enhanced Learning in Children Word Count: 3700 Words (main text and footnotes) Abstract · In older elementary school children, testing enhances the learning of new in- formation by reducing

  12. Effect of driver impedance on dense plasma focus Z-pinch neutron yield

    SciTech Connect (OSTI)

    Sears, Jason E-mail: schmidt36@llnl.gov; Link, Anthony E-mail: schmidt36@llnl.gov; Schmidt, Andrea E-mail: schmidt36@llnl.gov; Welch, Dale

    2014-12-15

    The Z-pinch phase of a dense plasma focus (DPF) heats the plasma by rapid compression and accelerates ions across its intense electric fields, producing neutrons through both thermonuclear and beam-target fusion. Driver characteristics have empirically been shown to affect performance, as measured by neutron yield per unit of stored energy. We are exploring the effect of driver characteristics on DPF performance using particle-in-cell (PIC) simulations of a kJ scale DPF. In this work, our PIC simulations are fluid for the run-down phase and transition to fully kinetic for the pinch phase, capturing kinetic instabilities, anomalous resistivity, and beam formation during the pinch. The anode-cathode boundary is driven by a circuit model of the capacitive driver, including system inductance, the load of the railgap switches, the guard resistors, and the coaxial transmission line parameters. It is known that the driver impedance plays an important role in the neutron yield: first, it sets the peak current achieved at pinch time; and second, it affects how much current continues to flow through the pinch when the pinch inductance and resistance suddenly increase. Here we show from fully kinetic simulations how total neutron yield depends on the impedance of the driver and the distributed parameters of the transmission circuit. Direct comparisons between the experiment and simulations enhance our understanding of these plasmas and provide predictive design capability for neutron source applications.

  13. Grid Parity for Residential Photovoltaics in the United States: Key Drivers and Sensitivities; Preprint

    SciTech Connect (OSTI)

    Ong, S.; Denholm, P.; Clark, N.

    2012-08-01

    In this report, we analyze PV break-even costs for U.S. residential customers. We evaluate some key drivers of grid parity both regionally and over time. We also examine the impact of moving from flat to time-of-use (TOU) rates, and we evaluate individual components of the break-even cost, including effect of rate structure and various incentives. Finally, we examine how PV markets might evolve on a regional basis considering the sensitivity of the break-even cost to four major drivers: technical performance, financing parameters, electricity prices and rates, and policies. We find that electricity price rather than technical parameters are in general the key drivers of the break-even cost of PV. Additionally, this analysis provides insight about the potential viability of PV markets.

  14. The effects of gardening on quality of life of older adults living in long-term care settings 

    E-Print Network [OSTI]

    Hartman, Ashley Irene

    2002-01-01

    As the percentage of people 65 years of age and older increases each year, quality of life for older adults becomes an increasingly important issue. Encompassing such areas as health care, psychology, and sociology, professionals are seeking...

  15. Nearby Outdoor Environmental Support of Older Adults' Yard Activities, Neighborhood Walking and Independent Living in the Community 

    E-Print Network [OSTI]

    Wang, Zhe

    2011-02-22

    Aging is a global phenomenon. Ways to sustain older adults' aging-in-place in the 'community at-large' (defined as traditional communities where most people live) have been overlooked. Consciously engaging in physical activity helps older adults...

  16. Fact #845 November 3, 2014 From 1970 to 2013 the Share of Older Vehicles in Operation has Increased

    Broader source: Energy.gov [DOE]

    In 1970 only 3% of the cars in operation were 15 years old or older. With cars lasting much longer today, 19% of cars in operation in 2013 were that same category. The 15 years old and older...

  17. Fact #845: November 3, 2014 From 1970 to 2013 the Share of Older Vehicles in Operation has Increased – Dataset

    Broader source: Energy.gov [DOE]

    Excel file with dataset for Fact #845: From 1970 to 2013 the Share of Older Vehicles in Operation has Increased

  18. A > 89% Efficient LED Driver with 0.5V Supply Voltage for Applications Requiring Low Average Current

    E-Print Network [OSTI]

    Perrott, Michael

    and that it lowers power consumption of the primarily digital architecture of the sensor [3]. However, red LEDs monitoring system [3] Since the LED driver is the dominant source of power consumption in this system [4A > 89% Efficient LED Driver with 0.5V Supply Voltage for Applications Requiring Low Average

  19. An analysis of factors contributing to train-involved crashes 

    E-Print Network [OSTI]

    Cooner, Scott Allen

    1995-01-01

    , light conditions, driver race and sex, accident severity, location type, and roadway class were statistically different compared to the corresponding national and statewide frequency distributions. The analysis of the research hypotheses showed...

  20. On an integral involving the digamma function

    E-Print Network [OSTI]

    Donal F. Connon

    2012-12-09

    We consider several possible approaches to evaluating an integral involving the digamma function and a related logarithmic series.

  1. Issues Related to Wisconsin "Failure to Pay Forfeitures" Driver's License Suspensions

    E-Print Network [OSTI]

    Saldin, Dilano

    their employment options and placing them at risk in the criminal justice system when found "driving while suspended" to and from work. Lack of a driver's license is a particularly serious barrier to employment further place themselves at high risk within the criminal justice system ­ for illegal driving, increased

  2. Offshore Wind Turbine Design: Addressing Uncertainty Drivers Sten Frandsen Niels Jacob Tarp-Johansen

    E-Print Network [OSTI]

    the next generation of offshore wind farms are designed. The aim of this paper is to discuss existingOffshore Wind Turbine Design: Addressing Uncertainty Drivers Sten Frandsen Niels Jacob Tarp@civil.auc.dk leje@elsam-eng.com Abstract: Current offshore wind turbine design methods have matured to a 1st

  3. 2002-21-0041 Performance Driver Information Systems, Enhancing the Fun-to-Drive Equation

    E-Print Network [OSTI]

    with the vehicle chassis in the form of autocross racing. Whatever the form, people like to drive their cars Copyright © 2002 Society of Automotive Engineers, Inc. ABSTRACT Most driver information systems offered hopefully do not have to fight construction delays and congested traffic. People just don't use their cars

  4. TEM Driver's Test 2014 July 23 Berkeley Lab Materials Sciences Division

    E-Print Network [OSTI]

    : _____________________________ 1. Safety: Understand emergency shut down procedure Know emergency contact numbers Know where Liquid image #12; TEM Driver's Test 2014 July 23 11. Shut down Stop live camera image (if shutting down instrument) 12. Record session in log-book Record filament time, adviser, and any

  5. Multimodal Presentation of Local Danger Warnings for Drivers: A Situation-Dependent Assessment of Usability

    E-Print Network [OSTI]

    Theune, Mariët

    Multimodal Presentation of Local Danger Warnings for Drivers: A Situation-Dependent Assessment danger warning function. To achieve high-quality assistance, the communication mode needs to be adaptive. Moreover, regardless of communication mode, the local danger warning function was considered as the most

  6. Evolution on a Restless Planet: Were Environmental Variability and Environmental Change Major Drivers of Human Evolution?

    E-Print Network [OSTI]

    Richerson, Peter J.

    223 7 Evolution on a Restless Planet: Were Environmental Variability and Environmental Change Major Drivers of Human Evolution? Peter J. Richerson, Robert L. Bettinger, and Robert Boyd 7.1 Introduction Two kinds of factors set the tempo and direction of organic and cultural evolution, those external to biotic

  7. Evolution styles: using architectural knowledge as an evolution driver Carlos E. Cuesta1

    E-Print Network [OSTI]

    Perry, Dewayne E.

    Evolution styles: using architectural knowledge as an evolution driver Carlos E. Cuesta1 , Elena+D, 02006, Albacete, Spain ABSTRACT Software evolution is an increasingly challenging and compelling concern software evolution is carried out, software architecture emerges as one of the cornerstones that should

  8. Evolution in plant populations as a driver of ecological changes in arthropod communities

    E-Print Network [OSTI]

    Vellend, Mark

    Evolution in plant populations as a driver of ecological changes in arthropod communities Marc T. J of Ecology and Evolution, Centre for the Analysis of Genome Evolution and Function, University of Toronto, 25-ranging impacts on species interactions, but the effects that ongoing evolution has on the temporal ecological

  9. Driver Selection Integration with Utility System Design Li Sun, Robin Smith

    E-Print Network [OSTI]

    Ahrendt, Wolfgang

    Driver options · Electric motor · Helper motor and generator · Steam turbine · Gas turbine · Combustion and energy efficiency · Flexibility and reliability · Others VHP HP MP LP Steam turbines HRSG Gas turbine, M13 9PL, UK Utility system design analysis Main components: - Fuel - Steam mains - Steam generation

  10. Revisiting the parameterization of potential evaporation as a driver of long-term water balance trends

    E-Print Network [OSTI]

    Dai, Aiguo

    /or Runoff. Most regions in the world lie in the continuum between the water and energy limits, reachingRevisiting the parameterization of potential evaporation as a driver of long-term water balance, evaporative flux and runoff simulated by the water balance model underlying the Palmer Drought Severity Index

  11. PachyRand: SQL Randomization for the PostgreSQL JDBC Driver Extended Abstract

    E-Print Network [OSTI]

    PachyRand: SQL Randomization for the PostgreSQL JDBC Driver Extended Abstract Michael E. Locasto content stored in SQL databases. Such systems take input directly from the client via HTML forms. Without proper input validation, these systems are vulnerable to SQL injection at- tacks. The predominant defense

  12. A Flexible Active-Matrix Electronic Paper With Integrated Display Driver Using The -Czochralski

    E-Print Network [OSTI]

    A Flexible Active-Matrix Electronic Paper With Integrated Display Driver Using The µ on the display itself. The display is flexible, including the driving electronics. Technology used offers great possibilities for future applications e.g. flexible electronics, three dimensional IC, System-on-Panel, ultra

  13. THE PRIMARY DRIVER of today's com-mercial electronics market is time. Portable

    E-Print Network [OSTI]

    Sandborn, Peter

    shorter market windows. The very existence of these products depends on finding quick design solutions to market is combining manufacturing information with application- specific design information as earlyTHE PRIMARY DRIVER of today's com- mercial electronics market is time. Portable computers, cellular

  14. Extending parental mentoring using an event-triggered video intervention in rural teen drivers

    E-Print Network [OSTI]

    Lee, John D.

    . During the initial phase of learning, adult or parental supervision often provides such guidance. However, once teens obtain their license, adult supervision is no longer mandated, and teens are left to teach their teens even after they begin driving independently. Twenty-six 16- to 17-year-old drivers

  15. HIGH INTENSITY LINAC DRIVER FOR THE SPIRAL-2 PROJECT : DESIGN OF SUPERCONDUCTING 88 MHZ QUARTER WAVE

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    . For the high-energy section of the linac, a superconducting 88 MHz Quarter Wave Resonator (beta 0.12) has been WAVE RESONATORS (BETA 0.12), POWER COUPLERS AND CRYOMODULES T. Junquera, G. Olry, H. Saugnac, J Abstract A superconducting linac driver, delivering deuterons with an energy up to 40 MeV (5 mA) and heavy

  16. Driver Models For Timing And Noise Analysis Bogdan Tutuianu and Ross Baldick

    E-Print Network [OSTI]

    Baldick, Ross

    Driver Models For Timing And Noise Analysis Bogdan Tutuianu and Ross Baldick Abstract and ways to model and analyze it is given in [23]. Other tools and methodologies for functional noise analysis are proposed in [19], [10] and [1]. Special circuit modeling techniques to asses global noise

  17. The Peril of Fragmentation: Security Hazards in Android Device Driver Customizations

    E-Print Network [OSTI]

    The Peril of Fragmentation: Security Hazards in Android Device Driver Customizations Xiaoyong Zhou of Illinois at Urbana-Champaign Email: naveed2@illinois.edu Abstract--Android phone manufacturers are under the per- petual pressure to move quickly on their new models, continu- ously customizing Android to fit

  18. FEPMA: Fine-Grained Event-Driven Power Meter for Android Smartphones Based on Device Driver

    E-Print Network [OSTI]

    Pedram, Massoud

    FEPMA: Fine-Grained Event-Driven Power Meter for Android Smartphones Based on Device Driver Layer for providing highly accurate and nearly instantaneous estimates of power dis- sipation in an Android smartphone the Android operating system to provide information about power/performance state changes of various

  19. A fuel economy optimization system with applications in vehicles with human drivers and autonomous vehicles

    E-Print Network [OSTI]

    Wu, Changxu (Sean)

    A fuel economy optimization system with applications in vehicles with human drivers and autonomous University of New York, Buffalo, USA a r t i c l e i n f o Keywords: Vehicle fuel economy Eco-driving Human developed and validated a new fuel-economy optimization system (FEOS), which receives input from vehicle

  20. Tree mortality in the eastern and central United States: patterns and drivers

    E-Print Network [OSTI]

    Moorcroft, Paul R.

    Tree mortality in the eastern and central United States: patterns and drivers M I C H A E L C . D I rate due to the small sample size of deaths within individual studies. Still, life cycle analyses have, such as the loss of >1.2 mil- lion ha of pinyon pine forest in the southwestern United States following the 2002

  1. Your Smartphone Can Watch the Road and You: Mobile Assistant for Inattentive Drivers

    E-Print Network [OSTI]

    Nelakuditi, Srihari

    -reported motor vehicle crashes occurred in the United States in 2007 [1]. Around 41000 people lost their lives of the leading causes of death. While lane departure warning, blind spot warning, and driver attention monitoring which results in increased latency and decreased frame rate. Fig. 1 shows the frame rate achieved

  2. An unsteady wave driver for narrowbanded waves: modeling nearshore circulation driven by wave groups

    E-Print Network [OSTI]

    Kirby, James T.

    An unsteady wave driver for narrowbanded waves: modeling nearshore circulation driven by wave Abstract In this paper, we derive an unsteady refraction­diffraction model for narrowbanded water waves for use in computing coupled wave­current motion in the nearshore. The end result is a variable

  3. Stochastic Behaviour of the Electricity Bid Stack: from Fundamental Drivers to Power Prices

    E-Print Network [OSTI]

    Howison, Sam

    Stochastic Behaviour of the Electricity Bid Stack: from Fundamental Drivers to Power Prices Michael) 23 October 2008 Abstract We develop a fundamental model for spot electricity prices, based on stochastic processes for underlying factors (fuel prices, power demand and generation capacity availability

  4. ORIGINAL PAPER Species diversity and drivers of spread of alien fungi

    E-Print Network [OSTI]

    ORIGINAL PAPER Species diversity and drivers of spread of alien fungi (sensu lato) in Europe February 2009 Ó Springer Science+Business Media B.V. 2009 Abstract A first comprehensive inventory of alien at the two spatial scales. Some taxonomic/phylogenetic orders were shown to be over-represented in alien

  5. The ITRS Design Technology and System Drivers Roadmap: Process and Status

    E-Print Network [OSTI]

    Kahng, Andrew B.

    The ITRS Design Technology and System Drivers Roadmap: Process and Status Andrew B. Kahng CSE (TWG) is one of 16 working groups in the International Technology Roadmap for Semiconduc- tors (ITRS) effort. It is responsible for the ITRS' Design Chap- ter, which roadmaps design technology requirements

  6. IMPACT OF BEAM TRANSPORT METHOD ON CHAMBER AND DRIVER DESIGN FOR

    E-Print Network [OSTI]

    California at San Diego, University of

    IMPACT OF BEAM TRANSPORT METHOD ON CHAMBER AND DRIVER DESIGN FOR HEAVY ION INERTIAL FUSION ENERGY D National Laboratory, Berkeley, California 94720 W. M. SHARP Lawrence Livermore National Laboratory, Livermore, California 94550 ARIES-IFE TEAM Received June 1, 2003 Accepted for Publication February 3, 2004

  7. What kind of charging infrastructure do Chevrolet Volts Drivers in The EV Project use?

    SciTech Connect (OSTI)

    John Smart

    2013-09-01

    This report summarizes key conclusions from analysis of data collected from Chevrolet Volts participating in The EV Project. Topics include how much Volt drivers charge at level 1 vs. level 2 rates and how much they charge at home vs. away from home.

  8. Refueling Behavior of Flexible Fuel Vehicle Drivers in the Federal Fleet

    SciTech Connect (OSTI)

    Daley, R.; Nangle, J.; Boeckman, G.; Miller, M.

    2014-05-01

    Federal fleets are a frequent subject of legislative and executive efforts to lead a national transition to alternative fuels and advanced vehicle technologies. Section 701 of the Energy Policy Act of 2005 requires that all dual-fueled alternative fuel vehicles in the federal fleet be operated on alternative fuel 100% of the time when they have access to it. However, in Fiscal Year (FY) 2012, drivers of federal flex fuel vehicles (FFV) leased through the General Services Administration refueled with E85 24% of the time when it was available--falling well short of the mandate. The U.S. Department of Energy's National Renewable Energy Laboratory completed a 2-year Laboratory Directed Research and Development project to identify the factors that influence the refueling behavior of federal FFV drivers. The project began with two primary hypotheses. First, information scarcity increases the tendency to miss opportunities to purchase E85. Second, even with perfect information, there are limits to how far drivers will go out of their way to purchase E85. This paper discusses the results of the project, which included a June 2012 survey of federal fleet drivers and an empirical analysis of actual refueling behavior from FY 2009 to 2012. This research will aid in the design and implementation of intervention programs aimed at increasing alternative fuel use and reducing petroleum consumption.

  9. Megafauna biomass tradeoff as a driver of Quaternary and future extinctions

    E-Print Network [OSTI]

    Barnosky, Anthony D.

    Megafauna biomass tradeoff as a driver of Quaternary and future extinctions Anthony D. Barnosky,000 and 3,000 years ago. Estimates of megafauna biomass (including hu- mans as a megafauna species) for before, during, and after the extinction episode suggest that growth of human biomass largely matched

  10. Methane storms as a driver of Titan's dune orientation

    E-Print Network [OSTI]

    Charnay, Benjamin; Rafkin, Scot; Narteau, Clément; Lebonnois, Sébastien; Rodriguez, Sébastien; Pont, Sylvain Courrech du; Lucas, Antoine

    2015-01-01

    Titan's equatorial regions are covered by eastward propagating linear dunes. This direction is opposite to mean surface winds simulated by Global Climate Models (GCMs), which are oriented westward at these latitudes, similar to trade winds on Earth. Different hypotheses have been proposed to address this apparent contradiction, involving Saturn's gravitational tides, large scale topography or wind statistics, but none of them can explain a global eastward dune propagation in the equatorial band. Here we analyse the impact of equinoctial tropical methane storms developing in the superrotating atmosphere (i.e. the eastward winds at high altitude) on Titan's dune orientation. Using mesoscale simulations of convective methane clouds with a GCM wind profile featuring superrotation, we show that Titan's storms should produce fast eastward gust fronts above the surface. Such gusts dominate the aeolian transport, allowing dunes to extend eastward. This analysis therefore suggests a coupling between superrotation, tro...

  11. Outcomes After Intensity-Modulated Versus Conformal Radiotherapy in Older Men With Nonmetastatic Prostate Cancer

    SciTech Connect (OSTI)

    Bekelman, Justin E.; Mitra, Nandita; Efstathiou, Jason; Liao Kaijun; Sunderland, Robert; Yeboa, Deborah N.; Armstrong, Katrina

    2011-11-15

    Purpose: There is little evidence comparing complications after intensity-modulated (IMRT) vs. three-dimensional conformal radiotherapy (CRT) for prostate cancer. The study objective was to test the hypothesis that IMRT, compared with CRT, is associated with a reduction in bowel, urinary, and erectile complications in elderly men with nonmetastatic prostate cancer. Methods and Materials: We undertook an observational cohort study using registry and administrative claims data from the SEER-Medicare database. We identified men aged 65 years or older diagnosed with nonmetastatic prostate cancer in the United States between 2002 and 2004 who received IMRT (n = 5,845) or CRT (n = 6,753). The primary outcome was a composite measure of bowel complications. Secondary outcomes were composite measures of urinary and erectile complications. We also examined specific subsets of bowel (proctitis/hemorrhage) and urinary (cystitis/hematuria) events within the composite complication measures. Results: IMRT was associated with reductions in composite bowel complications (24-month cumulative incidence 18.8% vs. 22.5%; hazard ratio [HR] 0.86; 95% confidence interval [CI], 0.79-0.93) and proctitis/hemorrhage (HR 0.78; 95% CI, 0.64-0.95). IMRT was not associated with rates of composite urinary complications (HR 0.93; 95% CI, 0.83-1.04) or cystitis/hematuria (HR 0.94; 95% CI, 0.83-1.07). The incidence of erectile complications involving invasive procedures was low and did not differ significantly between groups, although IMRT was associated with an increase in new diagnoses of impotence (HR 1.27, 95% CI, 1.14-1.42). Conclusion: IMRT is associated with a small reduction in composite bowel complications and proctitis/hemorrhage compared with CRT in elderly men with nonmetastatic prostate cancer.

  12. Cognitive and neural correlates of memory retrieval in young and older adults

    E-Print Network [OSTI]

    O'Kane, Gail, 1965-

    2004-01-01

    (cont.) increased activity whenever recollection was attempted, independent of the level of recollection success. The results are consistent with the hypothesis that increased left-lateralized retrieval activity in older ...

  13. Parenting style and older children's and young adolescents' dietary intake and nutritional status 

    E-Print Network [OSTI]

    Kim, Mi Jeong

    2007-09-17

    neglected. The present study examined whether perceived parenting style and its dimensions are associated with older children�s/young adolescents� health outcomes, including self-concept, eating behaviors, physical activity behaviors, energy...

  14. Tracking Reading: Dual Task Costs of Oral Reading for Young Versus Older Adults

    E-Print Network [OSTI]

    Kemper, Susan; Bontempo, Daniel; Schmalzried, RaLynn Cheri; McKedy, Whitney; Tagliaferri, Bruno; Kieweg, Doug

    2014-02-01

    A digital pursuit rotor was used to monitor oral reading costs by time-locking tracking performance to the auditory wave form produced as young and older adults were reading out short paragraphs. Multilevel modeling was ...

  15. A Corpus Analysis of Spoken Smart-Home Interactions with Older Users 

    E-Print Network [OSTI]

    Möller, Sebastian; Gödde, Florian; Wolters, Maria

    2008-01-01

    In this paper, we present the collection and analysis of a spoken dialogue corpus obtained from interactions of older and younger users with a smart-home system. Our aim is to identify the amount and the origin of linguistic ...

  16. The Portrayal of Older Adults in Advertising: A Cross-National Review

    E-Print Network [OSTI]

    Zhang, Yan Bing; Harwood, Jake; Williams, Angie; Ylä nne-McEwen, Virpi; Wadleigh, Paul Mark

    2006-09-01

    From a multi-national perspective, this chapter provides an overview of a number of research programs examining portrayals of older adults in advertising. The research described includes both quantitative and qualitative analyses of the place...

  17. Growing minds: evaluating the effects of gardening on quality of life and obesity in older adults 

    E-Print Network [OSTI]

    Lillard, Aime Jo Sommerfeld

    2009-05-15

    Older adults represent a growing part of the population of the United States. Due to decreased physical activity, dietary changes, and alterations in metabolic rate this population is susceptible to an increased rate of diseases. The generation...

  18. THE PERSISTENCE OF INFERENCES IN MEMORY FOR YOUNGER AND OLDER ADULTS 

    E-Print Network [OSTI]

    Guillory, Jimmeka J.

    2010-07-14

    Younger and older adults’ susceptibility to the continued influence of inferences in memory was examined using a paradigm implemented by Wilkes and Leatherbarrow. Research has shown that younger adults have difficulty forgetting inferences they make...

  19. Multi-tasking, Executive Function, and Functional Abilities in Older Adults with Type 2 Diabetes Mellitus

    E-Print Network [OSTI]

    Rucker, Jason Lee

    2014-05-31

    of these executive impairments and their functional consequences in this population remain poorly understood. The primary purpose of this work was to determine whether older adults with type 2 diabetes demonstrated impairments in the executive process of multi...

  20. The influence of contagion information and behavior on older adolescents' perceptions of peers with chronic illness 

    E-Print Network [OSTI]

    Grizzle, Jonhenry Cordell

    2005-11-01

    To explore attributions about chronically ill peers, 545 older adolescents ages 17-26 read a short vignette describing a brief social encounter with a hypothetical peer suffering from a medical condition, and then responded ...

  1. Job Satisfaction, Work Environment, and Successful Aging: Determinants to Remain in Older Acute Care Nurses

    E-Print Network [OSTI]

    Wargo-Sugleris, Michele

    2015-01-01

    and the retention of older RNs. Nursing Leadership, 18(1),recent national surveys of RNs". Nursing Economics, 23(2),delaying retirement in RNs and can help in the development

  2. Older Adults with HIV/AIDS: Experiences of Stigma-The Use of Personal Strengths

    E-Print Network [OSTI]

    Chandran, Devyani

    2009-12-08

    This dissertation explores the stigma experiences of older adults who have HIV/AIDS, the personal strengths and other responses they have to these experiences, and whether they experienced personal growth as a result of their responses to stigma. A...

  3. Different effects of dual task demands on the speech of young and older adults

    E-Print Network [OSTI]

    Kemper, Susan; Herman, Ruth; Nartowicz, Jennifer

    2005-12-01

    Young and older adults provided language samples in response to elicitation questions while concurrently performing 3 different tasks. The language samples were scored on three dimensions: fluency, grammatical complexity, and content. Previous...

  4. Accounting for the Variation of Driver Aggression in the Simulation of Conventional and Advanced Vehicles

    SciTech Connect (OSTI)

    Neubauer, J.; Wood, E.

    2013-01-01

    Hybrid electric vehicles, plug-in hybrid electric vehicles, and battery electric vehicles offer the potential to reduce both oil imports and greenhouse gases, as well as to offer a financial benefit to the driver. However, assessing these potential benefits is complicated by several factors, including the driving habits of the operator. We focus on driver aggression, i.e., the level of acceleration and velocity characteristic of travel, to (1) assess its variation within large, real-world drive datasets, (2) quantify its effect on both vehicle efficiency and economics for multiple vehicle types, (3) compare these results to those of standard drive cycles commonly used in the industry, and (4) create a representative drive cycle for future analyses where standard drive cycles are lacking.

  5. Accounting for the Variation of Driver Aggression in the Simulation of Conventional and Advanced Vehicles: Preprint

    SciTech Connect (OSTI)

    Neubauer, J.; Wood, E.

    2013-03-01

    Hybrid electric vehicles, plug-in hybrid electric vehicles, and battery electric vehicles offer the potential to reduce both oil imports and greenhouse gases, as well as to offer a financial benefit to the driver. However, assessing these potential benefits is complicated by several factors, including the driving habits of the operator. We focus on driver aggression, i.e., the level of acceleration and velocity characteristic of travel, to (1) assess its variation within large, real-world drive datasets, (2) quantify its effect on both vehicle efficiency and economics for multiple vehicle types, (3) compare these results to those of standard drive cycles commonly used in the industry, and (4) create a representative drive cycle for future analyses where standard drive cycles are lacking.

  6. Ramsey Numbers Involving Cycles Stanislaw P. Radziszowski

    E-Print Network [OSTI]

    Radziszowski, Stanislaw P.

    Ramsey Numbers Involving Cycles Stanislaw P. Radziszowski Department of Computer Science Rochester and data on Ramsey numbers involving cycles. This survey is based on the author's 2009 revi- sion #12 of the Dynamic Survey DS1, "Small Ramsey Numbers", at the Electronic Journal of Combinatorics. Table of Contents

  7. RESEARCH INVOLVING PRISONERS DEFINITIONS AND EXAMPLES

    E-Print Network [OSTI]

    1 RESEARCH INVOLVING PRISONERS 05/30/2008 DEFINITIONS AND EXAMPLES The DUHS IRB reviews and approves research involving prisoners in compliance with 45 CFR 46 Subpart C and other applicable regulations and laws. The provisions of Subpart C apply whenever the research targets prisoners as subjects

  8. Managing the Drivers of Air Flow and Water Vapor Transport in Existing Single Family Homes (Revised)

    SciTech Connect (OSTI)

    Cummings, J.; Withers, C.; Martin, E.; Moyer, N.

    2012-10-01

    This document focuses on managing the driving forces which move air and moisture across the building envelope. While other previously published Measure Guidelines focus on elimination of air pathways, the ultimate goal of this Measure Guideline is to manage drivers which cause air flow and water vapor transport across the building envelope (and also within the home), control air infiltration, keep relative humidity (RH) within acceptable limits, avoid combustion safety problems, improve occupant comfort, and reduce house energy use.

  9. Managing the Drivers of Air Flow and Water Vapor Transport in Existing Single-Family Homes

    SciTech Connect (OSTI)

    Cummings, James; Withers, Charles; Martin, Eric; Moyer, Neil

    2012-10-01

    This report is a revision of an earlier report titled: Measure Guideline: Managing the Drivers of Air Flow and Water Vapor Transport in Existing Single-Family Homes. Revisions include: Information in the text box on page 1 was revised to reflect the most accurate information regarding classifications as referenced in the 2012 International Residential Code. “Measure Guideline” was dropped from the title of the report. An addition was made to the reference list.

  10. DRIVER ACCELERATOR DESIGN FOR THE 10 KW UPGRADE OF THE JEFFERSON LAB IR FEL

    E-Print Network [OSTI]

    DRIVER ACCELERATOR DESIGN FOR THE 10 KW UPGRADE OF THE JEFFERSON LAB IR FEL D. Douglas, S. V, Newport News, VA23606, USA Abstract An upgrade of the Jefferson Lab IR FEL [1] is now un- der construction. It will provide 10 kW output light power in a wavelength range of 2­10 µm. The FEL will be driven by a modest

  11. Design of a new main injector cavity for the Fermilab Proton Driver era

    SciTech Connect (OSTI)

    Wu, V.; Chen, A.; Qian, Z.; Wildman, D.W.; /Fermilab

    2005-05-01

    In the design report of the Fermilab Proton Driver [1], the Main Injector (MI) needs to be upgraded to a 2 MW machine. For the Main Injector radiofrequency (rf) upgrade, R&D efforts are launched to design and build a new rf system. This paper presents the new cavity design study for the rf system. The cavity is simulated with the design code Mafia [2].

  12. Where do Nissan Leaf drivers in The EV Project charge when they have the opportunity to charge at work?

    SciTech Connect (OSTI)

    John Smart; Don Scoffield

    2014-03-01

    This paper invesigates where Nissan Leaf drivers in the EV Project charge when they have the opportunity to charge at work. Do they charge at work, home, or some other location?

  13. Where do Chevrolet Volt drivers in The EV Project charge when they have the opportunity to charge at work?

    SciTech Connect (OSTI)

    John Smart; Don Scoffield

    2014-03-01

    This paper investigates where Chevy Volt drivers in the EV Project charge when they have the opportunity to charge at work. Do they charge at home, work, or some other location.

  14. How to Apply for a NYS License If after reading through the Drivers From Other Nations section on the following page, you decide that you need to apply for a NYS license,

    E-Print Network [OSTI]

    Alexandrova, Ivana

    11/19/14 How to Apply for a NYS License If after reading through the Drivers From Other Nations section on the following page, you decide that you need to apply for a NYS license, these are some basic for your test. http://dmv.ny.gov/driver-license/nys-dmv-drivers-manual-online-drivers- manual

  15. Break-Even Cost for Residential Photovoltaics in the United States: Key Drivers and Sensitivities

    SciTech Connect (OSTI)

    Denholm, P.; Margolis, R. M.; Ong, S.; Roberts, B.

    2009-12-01

    Grid parity--or break-even cost--for photovoltaic (PV) technology is defined as the point where the cost of PV-generated electricity equals the cost of electricity purchased from the grid. Break-even cost is expressed in $/W of an installed system. Achieving break-even cost is a function of many variables. Consequently, break-even costs vary by location and time for a country, such as the United States, with a diverse set of resources, electricity prices, and other variables. In this report, we analyze PV break-even costs for U.S. residential customers. We evaluate some key drivers of grid parity both regionally and over time. We also examine the impact of moving from flat to time-of-use (TOU) rates, and we evaluate individual components of the break-even cost, including effect of rate structure and various incentives. Finally, we examine how PV markets might evolve on a regional basis considering the sensitivity of the break-even cost to four major drivers: technical performance, financing parameters, electricity prices and rates, and policies. We find that local incentives rather than ?technical? parameters are in general the key drivers of the break-even cost of PV. Additionally, this analysis provides insight about the potential viability of PV markets.

  16. Analysis of the Ultra-fast Switching Dynamics in a Hybrid MOSFET/Driver

    SciTech Connect (OSTI)

    Tang, T.; Burkhart, C.; /SLAC

    2011-08-17

    The turn-on dynamics of a power MOSFET during ultra-fast, {approx} ns, switching are discussed in this paper. The testing was performed using a custom hybrid MOSFET/Driver module, which was fabricated by directly assembling die-form components, power MOSFET and drivers, on a printed circuit board. By using die-form components, the hybrid approach substantially reduces parasitic inductance, which facilitates ultra-fast switching. The measured turn on time of the hybrid module with a resistive load is 1.2 ns with an applied voltage of 1000 V and drain current of 33 A. Detailed analysis of the switching waveforms reveals that switching behavior must be interpreted differently in the ultra-fast regime. For example, the gate threshold voltage to turn on the device is observed to increase as the switching time decreases. Further analysis and simulation of MOSFET switching behavior shows that the minimum turn on time scales with the product of the drain-source on resistance and drain-source capacitance, R{sub DS(on)}C{sub OSS}. This information will be useful in power MOSFET selection and gate driver design for ultra-fast switching applications.

  17. Accounting for the Variation of Driver Aggression in the Simulation of Conventional and Advanced Vehicles (Presentation)

    SciTech Connect (OSTI)

    Neubauer, J.; Wood, E.

    2013-05-01

    This presentation discusses a method of accounting for realistic levels of driver aggression to higher-level vehicle studies, including the impact of variation in real-world driving characteristics (acceleration and speed) on vehicle energy consumption and different powertrains (e.g., conventionally powered vehicles versus electrified drive vehicles [xEVs]). Aggression variation between drivers can increase fuel consumption by more than 50% or decrease it by more than 20% from average. The normalized fuel consumption deviation from average as a function of population percentile was found to be largely insensitive to powertrain. However, the traits of ideal driving behavior are a function of powertrain. In conventional vehicles, kinetic losses dominate rolling resistance and aerodynamic losses. In xEVs with regenerative braking, rolling resistance and aerodynamic losses dominate. The relation of fuel consumption predicted from real-world drive data to that predicted by the industry-standard HWFET, UDDS, LA92, and US06 drive cycles was not consistent across powertrains, and varied broadly from the mean, median, and mode of real-world driving. A drive cycle synthesized by NREL's DRIVE tool accurately and consistently reproduces average real-world for multiple powertrains within 1%, and can be used to calculate the fuel consumption effects of varying levels of driver aggression.

  18. Survey of Laser Markets Relevant to Inertial Fusion Energy Drivers, information for National Research Council

    SciTech Connect (OSTI)

    Bayramian, A J; Deri, R J; Erlandson, A C

    2011-02-24

    Development of a new technology for commercial application can be significantly accelerated by leveraging related technologies used in other markets. Synergies across multiple application domains attract research and development (R and D) talent - widening the innovation pipeline - and increases the market demand in common components and subsystems to provide performance improvements and cost reductions. For these reasons, driver development plans for inertial fusion energy (IFE) should consider the non-fusion technology base that can be lveraged for application to IFE. At this time, two laser driver technologies are being proposed for IFE: solid-state lasers (SSLs) and KrF gas (excimer) lasers. This document provides a brief survey of organizations actively engaged in these technologies. This is intended to facilitate comparison of the opportunities for leveraging the larger technical community for IFE laser driver development. They have included tables that summarize the commercial organizations selling solid-state and KrF lasers, and a brief summary of organizations actively engaged in R and D on these technologies.

  19. HESFIRE: a global fire model to explore the role of anthropogenic and weather drivers

    SciTech Connect (OSTI)

    Le Page, Yannick LB; Morton, Douglas; Bond-Lamberty, Benjamin; Pereira, Jose M.; Hurtt, George C.

    2015-01-01

    Vegetation fires are a major driver of ecosystem dynamics and greenhouse gas emissions. Anticipating potential changes in fire activity and their impacts relies first on a realistic model of fire activity (e.g., fire incidence and interannual variability) and second on a model accounting for fire impacts (e.g., mortality and emissions). In this paper, we focus on our understanding of fire activity and describe a new fire model, HESFIRE (Human–Earth System FIRE), which integrates the influence of weather, vegetation characteristics, and human activities on fires in a stand-alone framework. It was developed with a particular emphasis on allowing fires to spread over consecutive days given their major contribution to burned areas in many ecosystems. A subset of the model parameters was calibrated through an optimization procedure using observation data to enhance our knowledge of regional drivers of fire activity and improve the performance of the model on a global scale. Modeled fire activity showed reasonable agreement with observations of burned area, fire seasonality, and interannual variability in many regions, including for spatial and temporal domains not included in the optimization procedure. Significant discrepancies are investigated, most notably regarding fires in boreal regions and in xeric ecosystems and also fire size distribution. The sensitivity of fire activity to model parameters is analyzed to explore the dominance of specific drivers across regions and ecosystems. The characteristics of HESFIRE and the outcome of its evaluation provide insights into the influence of anthropogenic activities and weather, and their interactions, on fire activity.

  20. Reliable, high repetition rate thyratron grid driver used with a magnetic modulator

    SciTech Connect (OSTI)

    Hill, J.V.; Ball, D.G.; Garrett, D.N.

    1991-06-14

    The Atomic Vapor Laser Isotope Separation (AVLIS) Program at Lawrence Livermore National Laboratory uses a magnetic modulator switched by a high voltage thyratron to drive a gas discharge laser. The thyratron trigger source must provide an extremely reliable, low jitter, high- rep-rate grid pulse. This paper describes a thyratron grid driver which delivers a 1.2 kV, 80 ns rise time grid pulse into a 50 ohm load at up to 4.5 kHz repetition rate and has demonstrated approximately 10,000 hours MTBF. Since the thyratron is used with a magnetic compression circuit having a delay time of 1.4 ms this grid driver incorporates a jitter compensation circuit to adjust the trigger timing of the thyratron to provide overall modulator/laser jitter of less than {plus minus} 2 ns. The specific grid driver requirements will be discussed followed by a description of the circuit design and theory of operation. Construction comments will be followed by performance data (for a specific thyratron and magnetic compression circuit), including pulse shape, jitter, and lifetime. 1 ref., 10 figs.

  1. Ethnic differences in parent involvement are moderated by type of involvement scale 

    E-Print Network [OSTI]

    Wong, Shuk Wa

    2006-10-30

    This study examines ethnic group differences on different dimensions of parentrated and teacher-rated parent involvement after adjusting for the influence of family socioeconomic factors, and the role of involvement scale ...

  2. Bounds on Some Ramsey Numbers Involving Quadrilateral +

    E-Print Network [OSTI]

    Radziszowski, Stanislaw P.

    Bounds on Some Ramsey Numbers Involving Quadrilateral + Xiaodong Xu Guangxi Academy of Sciences@cs.rit.edu Abstract. For graphs G 1 , G 2 , · · · , Gm , the Ramsey number R(G 1 , G 2 , · · · , Gm ) is defined Ramsey numbers involving quadrilateral C 4 , including R(C 4 , K 9 ) # 32, 19 # R(C 4 , C 4 , K 4 ) # 22

  3. Effective Cue Utilization Reduces Memory Errors in Older Adults Ayanna K. Thomas and John B. Bulevich

    E-Print Network [OSTI]

    Patel, Aniruddh D.

    Effective Cue Utilization Reduces Memory Errors in Older Adults Ayanna K. Thomas and John B utilization at retrieval. Retention interval and instructions at retrieval were manipulated within at retrieval (i.e., the cue utilization deficit hypothesis). The present study sought to differentiate between

  4. Somatic complaints in older adults: aging process or symptoms of depression 

    E-Print Network [OSTI]

    Gentry, Ruth Anne

    2013-02-22

    on those results, the scale was modified for the primary study, which re-assessed the scale reliability and examined scale validity. Participants in the primary study were older adults living in nursing homes and in the community. They were given the new...

  5. Use of seal-like robot PARO in sensory group therapy for older adults with dementia

    E-Print Network [OSTI]

    Sabanovic, Selma

    Use of seal-like robot PARO in sensory group therapy for older adults with dementia Wan-Ling Chang--This work presents the preliminary results of an eight- week study of the seal-like robot PARO being used adapted the concept of MSBT to the use of PARO as a multimodal sensory stimulus in a group activity

  6. A Robotically-Augmented Walker for Older Adults Jared Glover, David Holstius, Michael

    E-Print Network [OSTI]

    of endorsements, either expressed or implied, of the United States Government of the National Science Foundation The population growth rate of older adults age 65 and more is double that of the general population, a trend a leading cause of unintentional injury and death. Approximately one-third of accidental deaths in this age

  7. A RoboticallyAugmented Walker for Older Adults Jared Glover, David Holstius, Michael

    E-Print Network [OSTI]

    of endorsements, either expressed or implied, of the United States Government of the National Science Foundation The population growth rate of older adults age 65 and more is double that of the general population, a trend a leading cause of unintentional injury and death. Approximately one­third of accidental deaths in this age

  8. HESFIRE: a global fire model to explore the role of anthropogenic and weather drivers

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Le Page, Yannick LB; Morton, Douglas; Bond-Lamberty, Benjamin; Pereira, Jose M.; Hurtt, George C.

    2015-02-13

    Vegetation fires are a major driver of ecosystem dynamics and greenhouse gas emissions. Anticipating potential changes in fire activity and their impacts relies first on a realistic model of fire activity (e.g., fire incidence and interannual variability) and second on a model accounting for fire impacts (e.g., mortality and emissions). In this paper, we focus on our understanding of fire activity and describe a new fire model, HESFIRE (Human–Earth System FIRE), which integrates the influence of weather, vegetation characteristics, and human activities on fires in a stand-alone framework. It was developed with a particular emphasis on allowing fires to spreadmore »over consecutive days given their major contribution to burned areas in many ecosystems. A subset of the model parameters was calibrated through an optimization procedure using observation data to enhance our knowledge of regional drivers of fire activity and improve the performance of the model on a global scale. Modeled fire activity showed reasonable agreement with observations of burned area, fire seasonality, and interannual variability in many regions, including for spatial and temporal domains not included in the optimization procedure. Significant discrepancies are investigated, most notably regarding fires in boreal regions and in xeric ecosystems and also fire size distribution. The sensitivity of fire activity to model parameters is analyzed to explore the dominance of specific drivers across regions and ecosystems. The characteristics of HESFIRE and the outcome of its evaluation provide insights into the influence of anthropogenic activities and weather, and their interactions, on fire activity.« less

  9. Overview of proton drivers for neutrino super beams and neutrino factories

    SciTech Connect (OSTI)

    Chou, W.; /Fermilab

    2006-06-01

    There has been a world-wide interest in Proton Drivers in the past decade. Numerous design proposals have been presented in Asia, Europe and North America, ranging from low energy rapid cycling synchrotrons, normal or superconducting linacs to high energy slow cycling synchrotrons and FFAGs. One thing in common is that all these machines provide MW beam power and are used primarily for neutrino experiments. This paper gives an overview of these activities. In the last section the author expresses his personal opinion on the future of this field.

  10. Low-jitter high-power thyristor array pulse driver and generator

    DOE Patents [OSTI]

    Hanks, Roy L. (Byron, CA)

    2002-01-01

    A method and apparatus for generating low-jitter, high-voltage and high-current pulses for driving low impedance loads such as detonator fuses uses a MOSFET driver which, when triggered, discharges a high-voltage pre-charged capacitor into the primary of a toroidal current-multiplying transformer with multiple isolated secondary windings. The secondary outputs are suitable for driving an array of thyristors that discharge a precharged high-voltage capacitor and thus generating the required high-voltage and high-current pulse.

  11. Linear beam raster magnet driver based on H-bridge technique

    DOE Patents [OSTI]

    Sinkine, Nikolai I.; Yan, Chen; Apeldoorn, Cornelis; Dail, Jeffrey Glenn; Wojcik, Randolph Frank; Gunning, William

    2006-06-06

    An improved raster magnet driver for a linear particle beam is based on an H-bridge technique. Four branches of power HEXFETs form a two-by-two switch. Switching the HEXFETs in a predetermined order and at the right frequency produces a triangular current waveform. An H-bridge controller controls switching sequence and timing. The magnetic field of the coil follows the shape of the waveform and thus steers the beam using a triangular rather than a sinusoidal waveform. The system produces a raster pattern having a highly uniform raster density distribution, eliminates target heating from non-uniform raster density distributions, and produces higher levels of beam current.

  12. HIV/AIDS Prevention among The Male Population: Results of a Peer-Education Program For Taxicab and Tricycle Drivers in the Philippines

    E-Print Network [OSTI]

    Morisky, Donald E

    2008-01-01

    and truck drivers in the Philippines. Occupational SafetyLabour and Employment, Philippines. United Nations EconomicRisk Reduction Program in the Philippines: A Comprehensive

  13. Supplement Table 1. Mean environmental drivers at Brasil flux sites. Precipitation (Prec) from Tropical Rainfall Measuring Mission (TRMM), for site-specific tower measurement years and a

    E-Print Network [OSTI]

    Malhi, Yadvinder

    Supplement Table 1. Mean environmental drivers at Brasil flux sites. Precipitation (Prec) from #12;Supplement Table 2. Brasil flux sites instrumentation and measuring methods. *: non aspirated

  14. Some Ramsey Problems Involving Triangles -Computational Approach

    E-Print Network [OSTI]

    Radziszowski, Stanislaw P.

    Some Ramsey Problems Involving Triangles - Computational Approach Stanislaw P. Radziszowski at the Ramsey Theory Workshop DIMACS, Rutgers University, May 28, 2009 Definition 1. For graphs G and H, R(G, H graphs, and the multicolor Ramsey numbers R(G1, · · · , Gr). Computational problems for Ramsey numbers

  15. Fire Classifications Fires involving the ordinary

    E-Print Network [OSTI]

    Jia, Songtao

    , plastics, etc. Fires involving combustible or flammable liquids such as gasoline, kerosene, oils, grease to prevent fires. Personnel should neither create nor tolerate conditions that could cause or fuel a fire is protected by various devices such as smoke detectors, sprinkler systems, and manual fire alarm pull stations

  16. Environmental science and ecology involve studies

    E-Print Network [OSTI]

    Christensen, Dan

    Environmental science and ecology involve studies of the biosphere, hydro- sphere, and lithosphere in environmental science is conducted on spatial scales varying from a single algal cell to the Earth as a whole's environmental scientists require investigation by an interdisciplinary team, including members from several

  17. Review: Balancing Limiting Factors and Economic Drivers to Achieve Sustainable Midwestern US Agricultural Residue Feedstock Supplies

    SciTech Connect (OSTI)

    Wally W. Wilhelm; J. Richard Hess; Douglas L. Karlen; David J. Muth; Jane M. F. Johnson; John M. Baker; Hero T. Gollany; Jeff M. Novak; Diane E. Stott; Gary E. Varvel

    2010-10-01

    Advanced biofuels will be developed using cellulosic feedstock rather than grain or oilseed crops that can also be used for food and feed. To be sustainable, these new agronomic production systems must be economically viable without degrading soil resources. This review examines six agronomic factors that collectively define many of the limits and opportunities for harvesting crop residue for biofuel feedstock. These six “limiting factors” are discussed in relationship to economic drivers associated with harvesting corn (Zea mays L.) stover as a potential cellulosic feedstock. The limiting factors include soil organic carbon, wind and water erosion, plant nutrient balance, soil water and temperature dynamics, soil compaction, and off-site environmental impacts. Initial evaluations using the Revised Universal Soil Loss Equation 2.0 (RUSLE2) show that a single factor analysis based on simply meeting tolerable soil loss might indicate stover could be harvested sustainably, but the same analysis based on maintaining soil organic carbon shows the practice to be non-sustainable. Modifying agricultural management to include either annual or perennial cover crops is shown to meet both soil erosion and soil carbon requirements. The importance of achieving high yields and planning in a holistic manner at the landscape scale are also shown to be crucial for balancing limitations and drivers associated with renewable bioenergy production.

  18. Optimizing and Diversifying Electric Vehicle Driving Range for U.S. Drivers

    SciTech Connect (OSTI)

    Lin, Zhenhong [ORNL

    2014-01-01

    Properly determining the driving range is critical for accurately predicting the sales and social benefits of battery electric vehicles (BEVs). This study proposes a framework for optimizing the driving range by minimizing the sum of battery price, electricity cost, and range limitation cost referred to as the range-related cost as a measurement of range anxiety. The objective function is linked to policy-relevant parameters, including battery cost and price markup, battery utilization, charging infrastructure availability, vehicle efficiency, electricity and gasoline prices, household vehicle ownership, daily driving patterns, discount rate, and perceived vehicle lifetime. Qualitative discussion of the framework and its empirical application to a sample (N=36,664) representing new car drivers in the United States is included. The quantitative results strongly suggest that ranges of less than 100 miles are likely to be more popular in the BEV market for a long period of time. The average optimal range among U.S. drivers is found to be largely inelastic. Still, battery cost reduction significantly drives BEV demand toward longer ranges, whereas improvement in the charging infrastructure is found to significantly drive BEV demand toward shorter ranges. The bias of a single-range assumption and the effects of range optimization and diversification in reducing such biases are both found to be significant.

  19. Breakeven Cost for Residential Photovoltaics in the United States: Key Drivers and Sensitivities (Report Summary) (Presentation)

    SciTech Connect (OSTI)

    Denholm, P.; Margolis, R. M.; Ong, S.; Roberts, B.

    2009-12-01

    "Break-even cost" for photovoltaic (PV) technology is defined as the point where the cost of PV-generated electricity equals the cost of electricity purchased from the grid. Break-even cost is expressed in $/W of an installed system. Achieving break-even cost is a function of many variables. Consequently, break-even costs vary by location and time for a country, such as the United States, with a diverse set of resources, electricity prices, and other variables. In this presentation, we introduce an analysis of PV break-even costs for residential customers in the United States, including an evaluation of some of the key drivers of PV breakeven both regionally and over time. This presentation includes our methodology and presents results for both near-term residential breakeven costs(2009) and future market sensitivities of break-even costs (2015). See also the the report "Break-Even Cost for Residential Photovoltaics in the United States: Key Drivers and Sensitivities". Presentation for NREL/TP-6A2-45991.

  20. La neutrino factory del CERN e i problemi radiologici dell'annesso proton driver

    E-Print Network [OSTI]

    Bressan, Beatrice Alessandra

    2001-01-01

    The thesis, La Neutrino Factory del CERN e i problemi radiologici dell’annesso proton driver (CERN Neutrino Factory and the radiological problems of the annex proton driver), deals with the new particle accelerators for the post LHC (Large Hadron Collider) era. The first part of the work describes these innovative accelerators with particular emphasis on the muon collider which, producing ?+/?? collisions in the 100 GeV energy range, should explore deeply the Higgs Boson physics. The second part of the thesis describes the three-step scenario proposed for the muon accelerators: Neutrino Factory, Higgs Factory and a collider with TeV C.M. energy. The third chapter explains how a Neutrino Factory works. In a Neutrino Factory the neutrino beam is generated by high-energy muons decaying in a storage ring. The muons are produced by pions generated in a target bombarded by an intense proton beam. In the CERN project, the proton beam is produced by a super conducting LINAC (with 75 Hz frequency and 2.2 GeV ene...

  1. Reliability and Failure Modes of Solid-State Lighting Electrical Drivers Subjected to Accelerated Aging

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Lall, Pradeep; Sakalaukus, Peter; Davis, Lynn

    2015-02-19

    An investigation of an off-the-shelf solid-state lighting device with the primary focus on the accompanied light-emitting diode (LED) electrical driver (ED) has been conducted. A set of 10 EDs were exposed to temperature humidity life testing of 85% RH and 85 #14;C (85/85) without an electrical bias per the JEDEC standard JESD22-A101C in order to accelerate the ingress of moisture into the aluminum electrolytic capacitor (AEC) and the EDs in order to assess the reliability of the LED drivers for harsh environment applications. The capacitance and equivalent series resistance for each AEC inside the ED were measured using a handheldmore »LCR meter as possible leading indications of failure. The photometric quantities of a single pristine light engine were monitored in order to investigate the interaction between the light engine and the EDs. These parameters were used in assessing the overall reliability of the EDs. In addition, a comparative analysis has been conducted between the 85/85 accelerated test data and a previously published high-temperature storage life accelerated test of 135°C. The results of the 85/85 acceleration test and the comparative analysis are presented in this paper.« less

  2. A thirty-two clock hour driver education classroom curriculum guide 

    E-Print Network [OSTI]

    Richardson, William Lee

    1990-01-01

    A THIRTY-TWO CLOCK HOUR DRIVER EDUCATION CLASSROOM CURRICULUM GUIDE A R e c o r d o f St u d y by WILLIAM LEE RICHARDSON S u b m i t t e d t o t h e O f f i c e o f G r a d u a t e S t u d i e s o f Texas A&M U n i v e r s i t y i n p a r t i... a l f u l f i l l m e n t o f t h e r e q u i r e m e n t s f o r t h e de g r e e o f DOCTOR OF EDUCATION December 1990 M a j o r S u b j e c t : I n d u s t r i a l E d u c a t i o n A THIRTY-TWO CLOCK HOUR DRIVER EDUCATION CLASSROOM...

  3. Authorization and Driving History Form The following information will be retained on file by all agencies on their drivers authorized to operate a

    E-Print Network [OSTI]

    Harms, Kyle E.

    agencies on their drivers authorized to operate a State vehicle, or a private vehicle for state purposes ___________________________________________ Position: Staff_____ Faculty_____ Student_____ Is employee's primary purpose to drive vehicles? Yes_____ No/her private vehicle in the course and scope of employment? Yes_____ No_____ Date of last Driver Training

  4. Combined image and genomic analysis of high-grade serous ovarian cancer reveals PTEN loss as a common driver event and prognostic classifier

    E-Print Network [OSTI]

    Martins, Filipe C.; de Santiago, Ines; Trinh, Anne; Xian, Jian; Guo, Anne; Sayal, Karen; Jimenez-Linan, Mercedes; Deen, Suha; Driver, Kristy; Mack, Marie; Aslop, Jennifer; Pharoah, Paul D. P.; Markowetz, Florian; Brenton, James D.

    2014-12-17

    TP53 and BRCA1/2 mutations are the main drivers in high-grade serous ovarian carcinoma (HGSOC). We hypothesise that combining tissue phenotypes from image analysis of tumour sections with genomic profiles could reveal other significant driver events...

  5. HIGH-POWER FFAG-BASED HEAVY-ION AND PROTON DRIVERS

    SciTech Connect (OSTI)

    RUGGIERO,A.

    2007-10-01

    Fixed-Field Alternating-Gradient (FFAG) accelerators are being proposed as an alternative to Super-conducting Linacs (SCL), Rapid-Cycling Synchrotrons (RCS) and Cyclotrons for the acceleration of very intense Heavy-Ion and Proton beams in the medium energy range. One application is the acceleration of ions of Uranium-238 to an energy of 400 MeV/u, and the average power of 400 kWatt, and the other a 1-GeV Proton Driver with an average beam power of 10 MWatt. One or two FFAG rings are needed for acceleration of both beams. They adopt a Non-Scaling Lattice (NSL) to reduce the size and the cost of the accelerator. The continuous wave (CW) mode of operation is achieved with the method of Harmonic Number Jump (HNJ).

  6. Data-Driven Probabilistic Modeling and Verification of Human Driver Behavior D. Sadigh, K. Driggs-Campbell, A. Puggelli,

    E-Print Network [OSTI]

    Seshia, Sanjit A.

    Department of Electrical Engineering and Computer Sciences University of California, Berkeley. Berkeley, CA Introduction The problem of modeling driver behavior in cars has long been studied, due to its relevance to reduce the number of car fatalities (Cacciabue 2007). In particular, one of the major focuses

  7. TrafficView: A Driver Assistant Device for Traffic Monitoring based on Car-to-Car Communication

    E-Print Network [OSTI]

    Iftode, Liviu

    TrafficView: A Driver Assistant Device for Traffic Monitoring based on Car-to-Car Communication an intelligent transportation system, a common platform for inter-vehicle communication is needed. This platform, Directions, etc. Slide bar for areas infront or behind you Your car Other cars Fig. 1. Example of Traffic

  8. CarSafe: A Driver Safety App that Detects Dangerous Driving Behavior using Dual-Cameras on Smartphones

    E-Print Network [OSTI]

    Campbell, Andrew T.

    , Lorenzo Torresani1 , and Andrew T. Campbell1 Dartmouth College1 , Autonomous National University of Mexico the safety extras? Several research projects have designed vision-based algorithms to detect drowsiness (us classification pipelines at the right time. The front camera pipeline tracks the driver's head pose and direction

  9. Brazil’s Biofuels Scenario: What are the Main Drivers Which will Shape Investments in the Long Term?

    Broader source: Energy.gov [DOE]

    Breakout Session 3C—Fostering Technology Adoption III: International Market Opportunities in Bioenergy Brazil’s Biofuels Scenario: What are the Main Drivers Which will Shape Investments in the Long Term? Artur Milanez, Manager of Biofuels Department, Brazilian Development Bank

  10. The effects of neighborhood environments on the level of physical activity among older african american women in Texas 

    E-Print Network [OSTI]

    Shin, Woo Hwa

    2009-05-15

    The older African American women living Texas fall into one of the most inactive population segments. Recently, the importance of socio-ecological models on human health behavior and more complex associations between ...

  11. The influence of experiences with serious medical conditions on self-reported health behaviors in older adolescent university students 

    E-Print Network [OSTI]

    Cooper, Danielle Louise

    2006-08-16

    The purpose of this study was to examine the influence of experiences with cancer, diabetes, and cardiovascular disease on self-reported health behaviors in older adolescents/young adults, conceptualized as 17 to 24 years ...

  12. The impact of urban form on older adults : focusing on neighborhood design and baby boomers' local behavior

    E-Print Network [OSTI]

    Lee, Jae Seung, Ph. D. Massachusetts Institute of Technology

    2012-01-01

    The growing share of older adults across the globe raises concern about active and safe aging. This dissertation examines aging baby boomers' travel and social behavior resulting from neighborhood design. The body of the ...

  13. Apolipoprotein gene involved in lipid metabolism

    DOE Patents [OSTI]

    Rubin, Edward (Berkeley, CA); Pennacchio, Len A. (Sebastopol, CA)

    2007-07-03

    Methods and materials for studying the effects of a newly identified human gene, APOAV, and the corresponding mouse gene apoAV. The sequences of the genes are given, and transgenic animals which either contain the gene or have the endogenous gene knocked out are described. In addition, single nucleotide polymorphisms (SNPs) in the gene are described and characterized. It is demonstrated that certain SNPs are associated with diseases involving lipids and triglycerides and other metabolic diseases. These SNPs may be used alone or with SNPs from other genes to study individual risk factors. Methods for intervention in lipid diseases, including the screening of drugs to treat lipid-related or diabetic diseases are also disclosed.

  14. On the Utility of Antiprotons as Drivers for Inertial Confinement Fusion

    SciTech Connect (OSTI)

    Perkins, L J; Orth, C D; Tabak, M

    2003-10-20

    By contrast to the large mass, complexity and recirculating power of conventional drivers for inertial confinement fusion (ICF), antiproton annihilation offers a specific energy of 90MJ/{micro}g and thus a unique form of energy packaging and delivery. In principle, antiproton drivers could provide a profound reduction in system mass for advanced space propulsion by ICF. We examine the physics underlying the use of antiprotons ({bar p}) to drive various classes of high-yield ICF targets by the methods of volumetric ignition, hotspot ignition and fast ignition. The useable fraction of annihilation deposition energy is determined for both {bar p}-driven ablative compression and {bar p}-driven fast ignition, in association with 0-D and 1-D target burn models. Thereby, we deduce scaling laws for the number of injected antiprotons required per capsule, together with timing and focal spot requirements. The kinetic energy of the injected antiproton beam required to penetrate to the desired annihilation point is always small relative to the deposited annihilation energy. We show that heavy metal seeding of the fuel and/or ablator is required to optimize local deposition of annihilation energy and determine that a minimum of {approx}3x10{sup 15} injected antiprotons will be required to achieve high yield (several hundred megajoules) in any target configuration. Target gains - i.e., fusion yields divided by the available p - {bar p} annihilation energy from the injected antiprotons (1.88GeV/{bar p}) - range from {approx}3 for volumetric ignition targets to {approx}600 for fast ignition targets. Antiproton-driven ICF is a speculative concept, and the handling of antiprotons and their required injection precision - temporally and spatially - will present significant technical challenges. The storage and manipulation of low-energy antiprotons, particularly in the form of antihydrogen, is a science in its infancy and a large scale-up of antiproton production over present supply methods would be required to embark on a serious R&D program for this application.

  15. Genomic Aspects of Research Involving Polyploid Plants

    SciTech Connect (OSTI)

    Yang, Xiaohan [ORNL; Ye, Chuyu [ORNL; Tschaplinski, Timothy J [ORNL; Wullschleger, Stan D [ORNL; Tuskan, Gerald A [ORNL

    2011-01-01

    Almost all extant plant species have spontaneously doubled their genomes at least once in their evolutionary histories, resulting in polyploidy which provided a rich genomic resource for evolutionary processes. Moreover, superior polyploid clones have been created during the process of crop domestication. Polyploid plants generated by evolutionary processes and/or crop domestication have been the intentional or serendipitous focus of research dealing with the dynamics and consequences of genome evolution. One of the new trends in genomics research is to create synthetic polyploid plants which provide materials for studying the initial genomic changes/responses immediately after polyploid formation. Polyploid plants are also used in functional genomics research to study gene expression in a complex genomic background. In this review, we summarize the recent progress in genomics research involving ancient, young, and synthetic polyploid plants, with a focus on genome size evolution, genomics diversity, genomic rearrangement, genetic and epigenetic changes in duplicated genes, gene discovery, and comparative genomics. Implications on plant sciences including evolution, functional genomics, and plant breeding are presented. It is anticipated that polyploids will be a regular subject of genomics research in the foreseeable future as the rapid advances in DNA sequencing technology create unprecedented opportunities for discovering and monitoring genomic and transcriptomic changes in polyploid plants. The fast accumulation of knowledge on polyploid formation, maintenance, and divergence at whole-genome and subgenome levels will not only help plant biologists understand how plants have evolved and diversified, but also assist plant breeders in designing new strategies for crop improvement.

  16. Studies Of Coherent Synchrotron Radiation And Longitudinal Space Charge In The Jefferson Lab FEL Driver

    SciTech Connect (OSTI)

    Tennant, Christopher D.; Douglas, David R.; Li, Rui; Tsai, C.-Y.

    2014-12-01

    The Jefferson Laboratory IR FEL Driver provides an ideal test bed for studying a variety of beam dynamical effects. Recent studies focused on characterizing the impact of coherent synchrotron radiation (CSR) with the goal of benchmarking measurements with simulation. Following measurements to characterize the beam, we quantitatively characterized energy extraction via CSR by measuring beam position at a dispersed location as a function of bunch compression. In addition to operating with the beam on the rising part of the linac RF waveform, measurements were also made while accelerating on the falling part. For each, the full compression point was moved along the backleg of the machine and the response of the beam (distribution, extracted energy) measured. Initial results of start-to-end simulations using a 1D CSR algorithm show remarkably good agreement with measurements. A subsequent experiment established lasing with the beam accelerated on the falling side of the RF waveform in conjunction with positive momentum compaction (R56) to compress the bunch. The success of this experiment motivated the design of a modified CEBAF-style arc with control of CSR and microbunching effects.

  17. Performance of the accelerator driver of Jefferson Laboratory's free-electron laser

    SciTech Connect (OSTI)

    Bohn, C.L.; Benson, S.; Biallas, G.

    1999-04-01

    The driver of Jefferson Lab's kW-level infrared free-electron laser (FEL) is a superconducting, recirculating accelerator that recovers about 75% of the electron-beam power and converts it to radiofrequency power. In achieving first lasing, the accelerator operated straight-ahead to deliver 38 MeV, 1.1 mA cw current through the wiggler for lasing at wavelengths in the vicinity of 5 {mu}m. Just prior to first lasing, measured rms beam properties at the wiggler were 7.5{+-}1.5 mm-mr normalized transverse emittance, 26{+-}7 keV-deg longitudinal emittance, and 0.4{+-}0.1 ps bunch length which yielded a peak current of 60{+-}15A. The waste beam was then sent directly to a dump, bypassing the recirculation loop. Stable operation at up to 311 W cw was achieved in this mode. Commissioning the recirculation loop then proceeded. As of this Conference, the machine has recirculated cw average current up to 4 mA, and has lased cw with energy recover up to 710 W.

  18. Evaluation of EBR-II driver-fuel elements following an unprotected station blackout accident

    SciTech Connect (OSTI)

    Chang, L.K.; Bottcher, J.H.

    1986-01-01

    One of the current design objectives for a liquid metal reactor (LMR) is the inherent shutdown-cooling capability of the reactor, such that the reactor itself can safely reduce power following a total loss of pump power without activating the reactor shutdown system (RSS). Following a loss-of-flow (LOF) accident and a failure of RSS, in EBR-II, reactor core damage and plant restartability is of considerable interest. In the LOF event, high temperature in the reactor causes negative reactivity feedback that reduces reactor power. After an accident, reactor fuel performance is one of the factors used to assess the restartability of the plant. A thermal-hydraulic-neutronic analysis was performed to determine the response of the plant and the temperature of individual subassemblies. These temperatures were then used to assess the damage to driver fuel elements caused by the station blackout accident. The maximum depth of cladding wastage from molten eutectic at temperatures >715/sup 0/C was found to be 0.0053 mm for the hottest subassembly; this value is considerably less than the 0.28 mm cladding thickness. 12 refs.

  19. The high current, fast, 100ns, Linear Transformer Driver (LTD) developmental project at Sandia National Laboratories.

    SciTech Connect (OSTI)

    Ward, Kevin S.; Long, Finis W.; Sinebryukhov, Vadim A. (High Current Electronic Institute (HCEI), Tomsk, Russia); Kim, Alexandre A. (High Current Electronic Institute (HCEI), Tomsk, RUSSIA); Wakeland, Peter Eric (Ktech Corporation, Albuquerque, NM); McKee, G. Randall; Woodworth, Joseph Ray; McDaniel, Dillon Heirman; Fowler, William E.; Mazarakis, Michael Gerrassimos; Porter, John Larry, Jr.; Struve, Kenneth William; Stygar, William A.; LeChien, Keith R.; Matzen, Maurice Keith

    2010-04-01

    Sandia National Laboratories, Albuquerque, N.M., USA, in collaboration with the High Current Electronic Institute (HCEI), Tomsk, Russia, is developing a new paradigm in pulsed power technology: the Linear Transformer Driver (LTD) technology. This technological approach can provide very compact devices that can deliver very fast high current and high voltage pulses straight out of the cavity with out any complicated pulse forming and pulse compression network. Through multistage inductively insulated voltage adders, the output pulse, increased in voltage amplitude, can be applied directly to the load. The load may be a vacuum electron diode, a z-pinch wire array, a gas puff, a liner, an isentropic compression load (ICE) to study material behavior under very high magnetic fields, or a fusion energy (IFE) target. This is because the output pulse rise time and width can be easily tailored to the specific application needs. In this paper we briefly summarize the developmental work done in Sandia and HCEI during the last few years, and describe our new MYKONOS Sandia High Current LTD Laboratory.

  20. Biennial Workshop on DSP for In-Vehicle Systems, Kiel, Germany, 2011 Assessment of driver's distraction using perceptual evaluations, self assessments

    E-Print Network [OSTI]

    Busso, Carlos

    platform ­ a car equipped with multiple nonintrusive sensors [1, 9]. Following the de- finition provided causes of car accidents is drivers that become distracted by secondary tasks. There is a growing concern-in car ra

  1. Feasibility of developing a portable driver performance data acquisition system for human factors research: Design specifications. Volume 3

    SciTech Connect (OSTI)

    Carter, R.J.; Barickman, F.S.

    1998-01-01

    A two-phase, multi-year research program entitled ``development of a portable driver performance data acquisition system for human factors research was recently completed. The primary objective of the project was to develop a portable data acquisition system for crash avoidance research (DASCAR) that will allow driver performance data to be collected using a large variety of vehicle types and that would be capable of being installed on a given vehicle type within a relatively short-time frame. During Phase 1 a feasibility study for designing and fabricating DASCAR was conducted. In phase 2 of the research DASCAR was actually developed and validated. This technical memorandum documents the results from the feasibility study. It is subdivided into three volumes. Volume one addresses the last five items in the phase 1 research and the first issue in the second phase of the project. Volume 2 presents the related appendices. Volume three (this report) displays the design specifications developed for DASCAR during the ``develop design requirements and specifications for a portable driver performance data acquisition system`` task. Design specifications were assembled for each DASCAR element. The specifications were prepared in sufficient detail to allow a third party to use them to design, develop, procure, and subsequently construct the data acquisition system. This report also covers the background to the program.

  2. Assessing Energy Impact of Plug-In Hybrid Electric Vehicles: Significance of Daily Distance Variation over Time and Among Drivers

    SciTech Connect (OSTI)

    Lin, Zhenhong [ORNL; Greene, David L [ORNL

    2012-01-01

    Accurate assessment of the impact of plug-in hybrid electric vehicles (PHEVs) on petroleum and electricity consumption is a necessary step toward effective policies. Variations in daily vehicle miles traveled (VMT) over time and among drivers affect PHEV energy impact, but the significance is not well understood. This paper uses a graphical illustration, a mathematical derivation, and an empirical study to examine the cause and significance of such an effect. The first two methods reveal that ignoring daily variation in VMT always causes underestimation of petroleum consumption and overestimation of electricity consumption by PHEVs; both biases increase as the assumed PHEV charge-depleting (CD) range moves closer to the average daily VMT. The empirical analysis based on national travel survey data shows that the assumption of uniform daily VMT over time and among drivers causes nearly 68% underestimation of expected petroleum use and nearly 48% overestimation of expected electricity use by PHEVs with a 40-mi CD range (PHEV40s). Also for PHEV40s, consideration of daily variation in VMT over time but not among drivers similar to the way the utility factor curve is derived in SAE Standard SAE J2841 causes underestimation of expected petroleum use by more than 24% and overestimation of expected electricity use by about 17%. Underestimation of petroleum use and overestimation of electricity use increase with larger-battery PHEVs.

  3. A wide bandgap silicon carbide (SiC) gate driver for high-temperature and high-voltage applications

    SciTech Connect (OSTI)

    Lamichhane, Ranjan [University of Arkansas; Ericson, Milton Nance [ORNL; Frank, Steven Shane [ORNL; BRITTONJr., CHARLES L. [Oak Ridge National Laboratory (ORNL); Marlino, Laura D [ORNL; Mantooth, Alan [University of Arkansas; Francis, Matt [APEI, Inc.; Shepherd, Dr. Paul [University of Arkansas; Glover, Dr. Michael [University of Arkansas; Podar, Mircea [ORNL; Perez, M [University of Arkansas; Mcnutt, Tyler [APEI, Inc.; Whitaker, Mr. Bret [APEI, Inc.; Cole, Mr. Zach [APEI, Inc.

    2014-01-01

    Limitations of silicon (Si) based power electronic devices can be overcome with Silicon Carbide (SiC) because of its remarkable material properties. SiC is a wide bandgap semiconductor material with larger bandgap, lower leakage currents, higher breakdown electric field, and higher thermal conductivity, which promotes higher switching frequencies for high power applications, higher temperature operation, and results in higher power density devices relative to Si [1]. The proposed work is focused on design of a SiC gate driver to drive a SiC power MOSFET, on a Cree SiC process, with rise/fall times (less than 100 ns) suitable for 500 kHz to 1 MHz switching frequency applications. A process optimized gate driver topology design which is significantly different from generic Si circuit design is proposed. The ultimate goal of the project is to integrate this gate driver into a Toyota Prius plug-in hybrid electric vehicle (PHEV) charger module. The application of this high frequency charger will result in lighter, smaller, cheaper, and a more efficient power electronics system.

  4. Implementing an Employee Involvement Program Through an Innovation Competition

    E-Print Network [OSTI]

    Salichs, José G.

    2006-05-19

    . It is on these areas that it must be especially innovative to get advantage over its competitors. Moving in this direction, many organizations have recognized that the clue to innovation is employee involvement; an involvement that translates into assertive corporate...

  5. Solving convex problems involving powers using conic optimization

    E-Print Network [OSTI]

    Glineur, François

    Solving convex problems involving powers using conic optimization and a new self-concordant barrier CFG 07 Heidelberg University CFG 07 Solving convex problems involving powers using conic optimization remarks Future plans CFG 07 Solving convex problems involving powers using conic optimization 2 #12

  6. A Survey of Industrial Involvement in Open Source

    E-Print Network [OSTI]

    A Survey of Industrial Involvement in Open Source Øyvind Hauge and Andreas Røsdal {oyvind of industrial involvement in open source. The survey is performed in collaboration with participants from). The survey was performed to explore aspects of industrial involvement in open source, as industrial

  7. PRECLINICAL STUDY Prediction of lymph node involvement in breast cancer

    E-Print Network [OSTI]

    PRECLINICAL STUDY Prediction of lymph node involvement in breast cancer from primary tumor tissue- ther lymph node involvement in breast cancer is influenced by gene or miRNA expression of the primary tissue from a group of 96 breast cancer patients balanced for lymph node involvement using Affymetrix

  8. Energy for 500 Million Homes: Drivers and Outlook for Residential Energy Consumption in China

    SciTech Connect (OSTI)

    Zhou, Nan; McNeil, Michael A.; Levine, Mark

    2009-06-01

    China's rapid economic expansion has propelled it to the rank of the largest energy consuming nation in the world, with energy demand growth continuing at a pace commensurate with its economic growth. The urban population is expected to grow by 20 million every year, accompanied by construction of 2 billion square meters of buildings every year through 2020. Thus residential energy use is very likely to continue its very rapid growth. Understanding the underlying drivers of this growth helps to identify the key areas to analyze energy efficiency potential, appropriate policies to reduce energy use, as well as to understand future energy in the building sector. This paper provides a detailed, bottom-up analysis of residential building energy consumption in China using data from a wide variety of sources and a modelling effort that relies on a very detailed characterization of China's energy demand. It assesses the current energy situation with consideration of end use, intensity, and efficiency etc, and forecast the future outlook for the critical period extending to 2020, based on assumptions of likely patterns of economic activity, availability of energy services, technology improvement and energy intensities. From this analysis, we can conclude that Chinese residential energy consumption will more than double by 2020, from 6.6 EJ in 2000 to 15.9 EJ in 2020. This increase will be driven primarily by urbanization, in combination with increases in living standards. In the urban and higher income Chinese households of the future, most major appliances will be common, and heated and cooled areas will grow on average. These shifts will offset the relatively modest efficiency gains expected according to current government plans and policies already in place. Therefore, levelling and reduction of growth in residential energy demand in China will require a new set of more aggressive efficiency policies.

  9. Pulse shaping and energy storage capabilities of angularly multiplexed KrF laser fusion drivers

    SciTech Connect (OSTI)

    Lehmberg, R. H. [Research Support Instruments, Inc., Lanham, Maryland 20706 (United States); Giuliani, J. L.; Schmitt, A. J. [Plasma Physics Division, U.S. Naval Research Laboratory, Washington, DC 20375 (United States)

    2009-07-15

    This paper describes a rep-rated multibeam KrF laser driver design for the 500 kJ Inertial Fusion test Facility (FTF) recently proposed by NRL, then models its optical pulse shaping capabilities using the ORESTES laser kinetics code. It describes a stable and reliable iteration technique for calculating the required precompensated input pulse shape that will achieve the desired output shape, even when the amplifiers are heavily saturated. It also describes how this precompensation technique could be experimentally implemented in real time on a reprated laser system. The simulations show that this multibeam system can achieve a high fidelity pulse shaping capability, even for a high gain shock ignition pulse whose final spike requires output intensities much higher than the approx4 MW/cm{sup 2} saturation levels associated with quasi-cw operation; i.e., they show that KrF can act as a storage medium even for pulsewidths of approx1 ns. For the chosen pulse, which gives a predicted fusion energy gain of approx120, the simulations predict the FTF can deliver a total on-target energy of 428 kJ, a peak spike power of 385 TW, and amplified spontaneous emission prepulse contrast ratios I{sub ASE}/I<3x10{sup -7} in intensity and F{sub ASE}/F<1.5x10{sup -5} in fluence. Finally, the paper proposes a front-end pulse shaping technique that combines an optical Kerr gate with cw 248 nm light and a 1 mum control beam shaped by advanced fiber optic technology, such as the one used in the National Ignition Facility (NIF) laser.

  10. Age-Related Affective Modulation of the Startle Eyeblink Response: Older Adults Startle Most When Viewing Positive Pictures

    E-Print Network [OSTI]

    Mather, Mara

    Viewing Positive Pictures Michelle C. Feng, Christopher G. Courtney, Mara Mather, Michael E. Dawson and negative pictures from the International Affective Picture System had opposite effects on startle, with potentiated startle when viewing negative pictures compared to positive pictures. Older adults, on the other

  11. HealtH care equity for etHnic minority older adults Sharon Koehn & Melissa Badger, Eds.

    E-Print Network [OSTI]

    Kavanagh, Karen L.

    HealtH care equity for etHnic minority older adults Sharon Koehn & Melissa Badger, Eds. Gerontology Research Centre, Simon Fraser University June 2015 2015 #12;2 | HEALTH CARE EQUITY FOR ETHNIC MINORITY to the BC Ministry of Health, the Public Health Agency of Canada, Fraser Health, the Canadian Coalition

  12. Key regulatory drivers affecting shipments of mixed transuranic waste from Los Alamos National Laboratory to the Waste Isolation Pilot Plant

    SciTech Connect (OSTI)

    Schumann, P.B.; Bacigalupa, G.A.; Kosiewicz, S.T.; Sinkule, B.J.

    1997-02-01

    A number of key regulatory drivers affect the nature, scope, and timing of Los Alamos National Laboratory`s (LANL`s) plans for mixed transuranic (MTRU) waste shipments to the Waste Isolation Pilot Plant (WIPP), which are planned to commence as soon as possible following WIPP`s currently anticipated November, 1997 opening date. This paper provides an overview of some of the key drivers at LANL, particularly emphasizing those associated with the hazardous waste component of LANL`s MTRU waste (MTRU, like any mixed waste, contains both a radioactive and a hazardous waste component). The key drivers discussed here derive from the federal Resource Conservation and Recovery Act (RCRA) and its amendments, including the Federal Facility Compliance Act (FFCAU), and from the New Mexico Hazardous Waste Act (NMHWA). These statutory provisions are enforced through three major mechanisms: facility RCRA permits; the New Mexico Hazardous Waste Management Regulations, set forth in the New Mexico Administrative Code, Title 20, Chapter 4, Part 1: and compliance orders issued to enforce these requirements. General requirements in all three categories will apply to MTRU waste management and characterization activities at both WIPP and LANL. In addition, LANL is subject to facility-specific requirements in its RCRA hazardous waste facility permit, permit conditions as currently proposed in RCRA Part B permit applications presently being reviewed by the New Mexico Environment Department (NNED), and facility-specific compliance orders related to MTRU waste management. Likewise, permitting and compliance-related requirements specific to WIPP indirectly affect LANL`s characterization, packaging, record-keeping, and transportation requirements for MTRU waste. LANL must comply with this evolving set of regulatory requirements to begin shipments of MTRU waste to WIPP in a timely fashion.

  13. Agricultural green revolution as a driver of increasing atmospheric CO2 seasonal amplitude

    SciTech Connect (OSTI)

    Zeng, Ning; Zhao, Fang; Collatz, George; Kalnay, Eugenia; Salawitch, Ross J.; West, Tristram O.; Guanter, Luis

    2014-11-20

    The atmospheric carbon dioxide (CO2) record displays a prominent seasonal cycle that arises mainly from changes in vegetation growth and the corresponding CO2 uptake during the boreal spring and summer growing seasons and CO2 release during the autumn and winter seasons. The CO2 seasonal amplitude has increased over the past five decades, suggesting an increase in Northern Hemisphere biospheric activity. It has been proposed that vegetation growth may have been stimulated by higher concentrations of CO2 as well as by warming in recent decades, but such mechanisms have been unable to explain the full range and magnitude of the observed increase in CO2 seasonal amplitude. Here we suggest that the intensification of agriculture (the Green Revolution, in which much greater crop yield per unit area was achieved by hybridization, irrigation and fertilization) during the past five decades is a driver of changes in the seasonal characteristics of the global carbon cycle. Our analysis of CO2 data and atmospheric inversions shows a robust 15 per cent long-term increase in CO2 seasonal amplitude from 1961 to 2010, punctuated by large decadal and interannual variations. Using a terrestrial carbon cycle model that takes into account high-yield cultivars, fertilizer use and irrigation, we find that the long-term increase in CO2 seasonal amplitude arises from two major regions: the mid-latitude cropland between 256N and 606N and the high-latitude natural vegetation between 506N and 706 N. The long-term trend of seasonal amplitude increase is 0.311 ± 0.027 percent per year, of which sensitivity experiments attribute 45, 29 and 26 per cent to land-use change, climate variability and change, and increased productivity due to CO2 fertilization, respectively. Vegetation growth was earlier by one to two weeks, as measured by the mid-point of vegetation carbon uptake, and took up 0.5 petagrams more carbon in July, the height of the growing season, during 2001–2010 than in 1961–1970, suggesting that human land use and management contribute to seasonal changes in the CO2 exchange between the biosphere and the atmosphere.

  14. Rapid embedded wire heating via resistive guiding of laser-generated fast electrons as a hydrodynamic driver

    SciTech Connect (OSTI)

    Robinson, A. P. L.; Schmitz, H. [Central Laser Facility, STFC Rutherford-Appleton Laboratory, Didcot OX11 0QX (United Kingdom)] [Central Laser Facility, STFC Rutherford-Appleton Laboratory, Didcot OX11 0QX (United Kingdom); Pasley, J. [Central Laser Facility, STFC Rutherford-Appleton Laboratory, Didcot OX11 0QX (United Kingdom) [Central Laser Facility, STFC Rutherford-Appleton Laboratory, Didcot OX11 0QX (United Kingdom); York Plasma Institute, University of York, York YO10 5DD (United Kingdom)

    2013-12-15

    Resistively guiding laser-generated fast electron beams in targets consisting of a resistive wire embedded in lower Z material should allow one to rapidly heat the wire to over 100 eV over a substantial distance without strongly heating the surrounding material. On the multi-ps timescale, this can drive hydrodynamic motion in the surrounding material. Thus, ultra-intense laser solid interactions have the potential as a controlled driver of radiation hydrodynamics in solid density material. In this paper, we assess the laser and target parameters needed to achieve such rapid and controlled heating of the embedded wire.

  15. Microsoft Word - Number of Public Involvement Deliverables _2...

    National Nuclear Security Administration (NNSA)

    numerous (+150) video clips and raw video * Maintain the Public Involvement portion of web-based Environmental Management Information System (includes uploading briefings,...

  16. Probative Investigation of the Thermal Stability of Wastes Involved...

    Office of Environmental Management (EM)

    the Thermal Stability of Wastes Involved in February 2014 Waste Isolation Pilot Plant (WIPP) Waste Drum Breach Event Probative Investigation of the Thermal Stability of Wastes...

  17. Break-Even Cost for Residential Solar Water Heating in the United States: Key Drivers and Sensitivities

    SciTech Connect (OSTI)

    Cassard, H.; Denholm, P.; Ong, S.

    2011-02-01

    This paper examines the break-even cost for residential rooftop solar water heating (SWH) technology, defined as the point where the cost of the energy saved with a SWH system equals the cost of a conventional heating fuel purchased from the grid (either electricity or natural gas). We examine the break-even cost for the largest 1,000 electric and natural gas utilities serving residential customers in the United States as of 2008. Currently, the break-even cost of SWH in the United States varies by more than a factor of five for both electricity and natural gas, despite a much smaller variation in the amount of energy saved by the systems (a factor of approximately one and a half). The break-even price for natural gas is lower than that for electricity due to a lower fuel cost. We also consider the relationship between SWH price and solar fraction and examine the key drivers behind break-even costs. Overall, the key drivers of the break-even cost of SWH are a combination of fuel price, local incentives, and technical factors including the solar resource location, system size, and hot water draw.

  18. High-Temperature SiC Power Module with Integrated SiC Gate Drivers for Future High-Density Power Electronics Applications

    SciTech Connect (OSTI)

    Whitaker, Mr. Bret [APEI, Inc.; Cole, Mr. Zach [APEI, Inc.; Passmore, Mr. Brandon [APEI, Inc.; Mcnutt, Tyler [APEI, Inc.; Lostetter, Dr. Alex [APEI, Inc.; Ericson, Milton Nance [ORNL; Frank, Steven [ORNL; Britton Jr, Charles L [ORNL; Marlino, Laura D [ORNL; Mantooth, Alan [University of Arkansas; Francis, Matt [APEI, Inc.; Lamichhane, Ranjan [APEI, Inc.; Shepherd, Paul [APEI, Inc.; Glover, Michael [APEI, Inc.

    2014-01-01

    This paper presents a high-temperature capable intelligent power module that contains SiC power devices and SiC gate driver integrated circuits (ICs). The high-temperature capability of the SiC gate driver ICs allows for them to be packaged into the power module and be located physically close to the power devices. This provides a distinct advantage by reducing the gate driver loop inductance, which promotes high frequency operation, while also reducing the overall volume of the system through higher levels of integration. The power module was tested in a bridgeless-boost converter (Fig. 1) to determine the performance of the module in a system level application. The converter was operated with a switching frequency of 200 kHz with a peak output power of approximately 5 kW. The peak efficiency was found to be 97.5% at 2.9 kW.

  19. RESEARCH INVOLVING HUMANS University Policy No.: RH8105

    E-Print Network [OSTI]

    Victoria, University of

    1 RESEARCH INVOLVING HUMANS University Policy No.: RH8105 Classification: Research Approving: Mandated Review: September, 2017 Associated Procedures Procedures for Conducting Human Research PURPOSE 1.00 The purpose of this policy is to: a) set out provisions to ensure Research Involving Human Participants

  20. UNLV DIVISION OF RESEARCH POLICY ON RESEARCH INVOLVING HUMAN SUBJECTS

    E-Print Network [OSTI]

    Walker, Lawrence R.

    UNLV DIVISION OF RESEARCH POLICY ON RESEARCH INVOLVING HUMAN SUBJECTS RESPONsmLE ADMINISTRATOR: VICE PRESIDENT FOR RESEARCH RESPONSmLE OFFICE(S): OFFICE OF RESEARCH INTEGRITY - HUMAN SUBJECTS rules and procedures, when conducting research involving human subjects. ENTITIES AFFECTED BY Tms POLICY

  1. See the yellow handout, "Driver's License and State ID Information for NonUS Citizens" or visit the PennDOT website: www.dmv.state.pa.us/ for more details.

    E-Print Network [OSTI]

    See the yellow handout, "Driver's License and State ID Information for NonUS Citizens" or visit Administration (SSA) to A. If you are a student, confirm that id ti l A. Obtain a PA Driver's License Manual at OIE Submit all required documents and proofs Step 1 Step 2 Step 3 (For License Only) Step 4 Step 5

  2. Voluntary Associations and Their Involvement in Collaborative Forest Management 

    E-Print Network [OSTI]

    Lu, Jiaying

    2012-02-14

    . This dissertation was aimed at gaining a better understanding of outdoor recreation and environmental voluntary associations and their involvement in collaborative forest management. Five objectives guided this study: (1) assessing the organizational characteristics...

  3. Getting Involved in Manufacturing Day – College Educators Edition Webinar

    Broader source: Energy.gov [DOE]

    This webinar will help address questions on why and how community colleges, universities, and technical schools can get involved with MFG DAY.  Led by MFG DAY Co-Producers, the webinar will also...

  4. An exploration of meaningful involvement in ropes course programs 

    E-Print Network [OSTI]

    Haras, Katryna Stephanie

    2004-09-30

    Ropes course programs provide numerous benefits but what makes programs effective has been unclear. The purpose of the study was to: 1) determine if there was a measurable difference in meaningful involvement between the ...

  5. A fast enriched FEM for Poisson equations involving interfaces

    E-Print Network [OSTI]

    Huynh, Thanh Le Ngoc

    2008-01-01

    We develop a fast enriched finite element method for solving Poisson equations involving complex geometry interfaces by using regular Cartesian grids. The presence of interfaces is accounted for by developing suitable jump ...

  6. Aluminum and tungsten X-pinch experiments on 100 kA, 100 ns linear transformer driver stage

    SciTech Connect (OSTI)

    Wu Jian [Department of Engineering Physics, Tsinghua University, Beijing 10086 (China); Northwest Institute of Nuclear Technology, Xi'an 710024 (China); Sun Tieping; Wu Gang; Wang Liangping; Han Juanjuan; Li Mo; Cong Peitian; Qiu Aici [Northwest Institute of Nuclear Technology, Xi'an 710024 (China); Lv Min [Department of Engineering Physics, Tsinghua University, Beijing 10086 (China)

    2011-05-15

    X-pinch experiments have been carried out on a 100 kA, 100 ns linear transformer driver stage recently built up. The X-pinches exhibited a source size of about 10 {mu}m, a pulse duration of 3 ns, 3-5 keV radiation energy of 3.9 mJ, and a burst time jitter of tens of nanosecond with the 2-wire 8 {mu}m W X-pinch load. The generator output current and the X-pinch characteristics depended on the X-pinch wire materials in the tests. X-ray backlighting images from the insects showed the significant phase-contrast effect.

  7. IEEE TRANSACTIONS ON COMPUTER-AIDED DESIGN OF INTEGRATED CIRCUITS AND SYSTEMS, VOL. , NO. , 2012 1 Dynamic Driver Supply Voltage Scaling for Organic

    E-Print Network [OSTI]

    Pedram, Massoud

    Dynamic Driver Supply Voltage Scaling for Organic Light Emitting Diode Displays Donghwa Shin, Student, Fellow, IEEE Abstract--Organic light emitting diode (OLED) display is a self-illuminating device]. On the other hand, an organic light emitting diode (OLED) is self-illuminating using organic light emission

  8. Community assessments: Road maps to successful public involvement

    SciTech Connect (OSTI)

    Forrest, C.J. [Equinox Environmental Consultants, Wheaton, IL (United States)

    1995-12-01

    This paper presents a framework for performing comprehensive community assessments to increase the effectiveness of public involvement efforts. The community assessment process involves systematic and critical examination of beliefs, attitudes, opinions and knowledge of the many groups in the community. A good community assessment gathers information on the concerns or issues directly related to an environmental project as well as other important community issues to ensure development of an effective public involvement program. The framework discusses types of people and organizations that should be included in the community assessment interview process. It also delineates steps that persons charged with performing assessments can take to ensure that the views of all potential stakeholders are included--a necessary consideration in communities that are ethnically, racially, or economically diverse. Lastly, the framework discusses types of written materials that can be analyzed for additional insight into communities. For example, it discusses methods for reviewing past issues of the local newspaper to provide both validation of the information gathered during interviews and an understanding of the ways that community members give and receive information and respond to conflict or perceived threats. This framework is designed to show environmental professionals who are responsible for public involvement how to perform an initial community assessment. It provides illustrations of instances in which information vital to a successful public involvement effort has been uncovered through a careful assessment of the community. Both the U.S. EPA and the public have made clear their intentions to require increased public involvement. Many of these efforts will succeed or fail based on how well those charged with the public involvement component of environmental projects identify community issues and design communications programs that successfully reach all stakeholders.

  9. An Honors Thesis in English What does it involve?

    E-Print Network [OSTI]

    Martinez, Tony R.

    1 An Honors Thesis in English What does it involve? · Prospectus The prospectus is a document that establishes your intentions for your thesis and makes a strong case for why your project should constitute an Honors thesis. A strong thesis is usually a result of a well developed prospectus. Care and attention

  10. Research Summary Consultation and community involvement in forest planning

    E-Print Network [OSTI]

    Research Summary Consultation and community involvement in forest planning: research in Cranborne of the Forestry Commission's `Long-Term Forest Plan' process. It also builds on various investigations into stakeholder analysis and the use of participatory tools in relation to Forest Design Plans (FDPs). The NFNF

  11. A Protein Export Pathway Involving Escherichia coli Porins

    E-Print Network [OSTI]

    McIntosh, Lawrence P.

    Structure Article A Protein Export Pathway Involving Escherichia coli Porins Gerd Prehna,1,2 Guijin@byron.biochem.ubc.ca (N.C.J.S.) DOI 10.1016/j.str.2012.04.014 SUMMARY Escherichia coli export the protein Yeb common to all E. coli strains has been reported, the mechanism of export has remained unclear. Herein, we

  12. Arm Coordination in Octopus Crawling Involves Unique Motor Control Strategies

    E-Print Network [OSTI]

    Hochner, Binyamin

    Report Arm Coordination in Octopus Crawling Involves Unique Motor Control Strategies Highlights d Octopuses use unique strategies to coordinate their arms in crawling d They can crawl in any direction relative to the facing (body) direction d Arms create pushing thrust by simple shortening

  13. Patterns of Arm Muscle Activation Involved in Octopus Reaching Movements

    E-Print Network [OSTI]

    Hochner, Binyamin

    Patterns of Arm Muscle Activation Involved in Octopus Reaching Movements Yoram Gutfreund,1 Tamar, Stazione Zoologica "A. Dohrn," Naples 80121, Italy The extreme flexibility of the octopus arm allows a basic invariant motor structure: a bend traveling from the base of the arm toward the tip (Gutfreund et

  14. BARNARD COLLEGE Termination of a Research Protocol Involving Human Subjects

    E-Print Network [OSTI]

    BARNARD COLLEGE Termination of a Research Protocol Involving Human Subjects Title: Principal) Study subjects: A total of _____ subjects were enrolled since the last report to the IRB. Since initial study approval on _____________ a total of _____ subjects have been enrolled in this study and ____ have

  15. Research Article Acetylcholinesterase in intestinal cell differentiation involves

    E-Print Network [OSTI]

    Tian, Weidong

    involved in the terminal differentiation of enterocytes. Butyrate, a short-chain fatty acid produced cell line Caco-2 following exposure to sodium butyrate (NaBT), using alkaline phosphatase (ALP, butyrate sodium, G2/M. Introduction The epithelium of the gastrointestinal tract is a complex and dynamic

  16. A1D04: Committee on Public Involvement in Transportation State of the Practice: White Paper on Public Involvement

    E-Print Network [OSTI]

    Handy, Susan L.

    -West Gateway Coordinating Council Public involvement is the process of two-way communication between citizen the passage of the Intermodal Surface Transportation Efficiency Act of 1991 (ISTEA), there has been underserved populations. ISTEA's directive was reinforced by the passage of the Transportation Equity Act

  17. Wire number dependence of the implosion dynamics, stagnation, and radiation output of tungsten wire arrays at Z driver

    SciTech Connect (OSTI)

    Mazarakis, Michael G.; Stygar, William A.; Sinars, Daniel B.; Cuneo, Michael E.; Nash, Thomas J.; Chandler, Gordon A.; Keith Matzen, M.; Porter, John L.; Struve, Kenneth W.; McDaniel, Dillon H. [Sandia National Laboratories, P.O. Box 5800, Albuquerque, New Mexico 87185 (United States); Deeney, Christopher E. [National Nuclear Security Administration, Washington, D.C. 20585 (United States); Douglas, Melissa R. [Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States); Chittenden, Jerry [Imperial College, London, SW and 2BW (United Kingdom)

    2011-11-15

    We report results of the experimental campaign, which studied the initiation, implosion dynamics, and radiation yield of tungsten wire arrays as a function of the wire number. The wire array dimensions and mass were those of interest for the Z-pinch driven Inertial Confinement Fusion (ICF) program. An optimization study of the x-ray emitted peak power, rise time, and full width at half maximum was effectuated by varying the wire number while keeping the total array mass constant and equal to {approx}5.8 mg. The driver utilized was the {approx}20-MA Z accelerator before refurbishment in its usual short pulse mode of 100 ns. We studied single arrays of 20-mm diameter and 1-cm height. The smaller wire number studied was 30 and the largest 600. It appears that 600 is the highest achievable wire number with present day's technology. Radial and axial diagnostics were utilized including crystal monochromatic x-ray backlighter. An optimum wire number of {approx}375 was observed which was very close to the routinely utilized 300 for the ICF program in Sandia.

  18. Comparison of electric and magnetic quadrupole focusing for the low energy end of an induction-linac-ICF (Inertial-Confinement-Fusion) driver

    SciTech Connect (OSTI)

    Kim, C.H.

    1987-04-01

    This report compares two physics designs of the low energy end of an induction linac-ICF driver: one using electric quadrupole focusing of many parallel beams followed by transverse combining; the other using magnetic quadrupole focusing of fewer beams without beam combining. Because of larger head-to-tail velocity spread and a consequent rapid current amplification in a magnetic focusing channel, the overall accelerator size of the design using magnetic focusing is comparable to that using electric focusing.

  19. High-Temperature SiC Power Module with Integrated SiC Gate Drivers for Future High-Density Power Electronics Applications

    SciTech Connect (OSTI)

    Whitaker, Mr. Bret [APEI, Inc.; Cole, Mr. Zach [APEI, Inc.; Passmore, Mr. Brandon [APEI, Inc.; Martin, Daniel [APEI, Inc.; Mcnutt, Tyler [APEI, Inc.; Lostetter, Dr. Alex [APEI, Inc.; Ericson, Milton Nance [ORNL; Frank, Steven Shane [ORNL; Britton Jr, Charles L [ORNL; Marlino, Laura D [ORNL; Mantooth, Alan [University of Arkansas; Francis, Dr. Matt [University of Arkansas; Lamichhane, Ranjan [University of Arkansas; Shepherd, Dr. Paul [University of Arkansas; Glover, Dr. Michael [University of Arkansas

    2015-01-01

    This paper presents the testing results of an all-silicon carbide (SiC) intelligent power module (IPM) for use in future high-density power electronics applications. The IPM has high-temperature capability and contains both SiC power devices and SiC gate driver integrated circuits (ICs). The high-temperature capability of the SiC gate driver ICs allows for them to be packaged into the power module and be located physically close to the power devices. This provides a distinct advantage by reducing the gate driver loop inductance, which promotes high frequency operation, while also reducing the overall volume of the system through higher levels of integration. The power module was tested in a bridgeless-boost converter to showcase the performance of the module in a system level application. The converter was initially operated with a switching frequency of 200 kHz with a peak output power of approximately 5 kW. The efficiency of the converter was then evaluated experimentally and optimized by increasing the overdrive voltage on the SiC gate driver ICs. Overall a peak efficiency of 97.7% was measured at 3.0 kW output. The converter s switching frequency was then increased to 500 kHz to prove the high frequency capability of the power module was then pushed to its limits and operated at a switching frequency of 500 kHz. With no further optimization of components, the converter was able to operate under these conditions and showed a peak efficiency of 95.0% at an output power of 2.1 kW.

  20. Workplace Charging Challenge Partner: JLA Public Involvement | Department

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyof Energy JLA Public Involvement Workplace

  1. 10 Gb/s Radiation-Hard VCSEL Array Driver K.K. Gan, P. Buchholz, S. Heidbrink, H. Kagan, R. Kass, J. Moore, D.S. Smith, M. Vogt, M. Ziolkowski

    E-Print Network [OSTI]

    Gan, K. K.

    to enhance the radiation-hardness. Each ASIC contains eight low voltage differential signal (LVDS) receivers10 Gb/s Radiation-Hard VCSEL Array Driver K.K. Gan, P. Buchholz, S. Heidbrink, H. Kagan, R. Kass, JV protons to a dose of 0.92x1015 1-MeV neq/cm2 and remain operational. For the 10 Gb/s VCSEL array driver

  2. Insulin signaling is involved in the regulation of worker division of labor in honey bee colonies

    E-Print Network [OSTI]

    Robinson, Gene E.

    of individuals. Nurse bees feed brood for the first 1­2 weeks of adult life, process and store food for another of individuals. Older bees acquire the colony's food by foraging for nectar and pollen, and the younger ``nurse expression in the brain and abdomen than did nurses, despite their low lipid stores. These differences

  3. Development of Patients' Decision Aid for Older Women With Stage I Breast Cancer Considering Radiotherapy After Lumpectomy

    SciTech Connect (OSTI)

    Wong, Jennifer; D'Alimonte, Laura; Angus, Jan; Paszat, Larry; Metcalfe, Kelly; Whelan, Tim; Llewellyn-Thomas, Hilary; Warner, Eiran; Franssen, Edmee; Szumacher, Ewa

    2012-09-01

    Purpose: To develop a patient decision aid (PtDA) for older women with Stage I, pathologically node negative, estrogen receptor-positive progesterone receptor-positive breast cancer who are considering adjuvant radiotherapy after lumpectomy and to examine its impact on patients' decision making. Methods and Materials: A PtDA was developed and evaluated in three steps according to the Ottawa Decision Support Framework: (1) needs assessment (n = 16); (2) Pilot I to examine PtDA acceptability (n = 12); and (3) Pilot II, a pretest posttest (n = 38) with older women with estrogen receptor-positive progesterone receptor-positive breast cancer after lumpectomy who were receiving adjuvant radiation therapy. Measures included patients' satisfaction with the PtDA, self-reported decisional conflict, level of distress, treatment-related knowledge, and choice predisposition. Results: The PtDA is a booklet that details each adjuvant treatment option's benefits, risks, and side effects tailored to the patient's clinical profile; includes a values clarification exercise; and includes steps to guide patients towards their decision. On the basis of qualitative comments and satisfaction ratings, all women thought that the PtDA was helpful and informative. In comparison with their baseline scores, patients had a statistically significant (p < 0.05) reduction in decisional conflict (adjusted mean difference [AMD], -7.18; 95% confidence interval [CI], -13.50 to 12.59); increased clarity of the benefits and risks (AMD, -10.86; CI, -20.33 to 21.49); and improved general treatment knowledge (AMD, 8.99; CI, 2.88-10.28) after using the PtDA. General trends were also reported in the patients' choice predisposition scores that suggested potential differences in treatment decision after PtDA use. Conclusions: This study provides evidence that this PtDA may be a helpful educational tool for this group of women. The quality of care for older breast cancer patients may be enhanced by the use of a tailored PtDA to help patients be better informed about their treatment options.

  4. Feasibility of developing a portable driver performance data acquisition system for human factors research: Technical tasks. Volume 1

    SciTech Connect (OSTI)

    Carter, R.J.; Barickman, F.S.; Spelt, P.F.; Schmoyer, R.L.; Kirkpatrick, J.R.

    1998-01-01

    A two-phase, multi-year research program entitled ``development of a portable driver performance data acquisition system for human factors research`` was recently completed. The primary objective of the project was to develop a portable data acquisition system for crash avoidance research (DASCAR) that will allow drive performance data to be collected using a large variety of vehicle types and that would be capable of being installed on a given vehicle type within a relatively short-time frame. During phase 1 a feasibility study for designing and fabricating DASCAR was conducted. In phase 2 of the research DASCAR was actually developed and validated. This technical memorandum documents the results from the feasibility study. It is subdivided into three volumes. Volume one (this report) addresses the last five items in the phase 1 research and the first issue in the second phase of the project. Volumes two and three present the related appendices, and the design specifications developed for DASCAR respectively. The six tasks were oriented toward: identifying parameters and measures; identifying analysis tools and methods; identifying measurement techniques and state-of-the-art hardware and software; developing design requirements and specifications; determining the cost of one or more copies of the proposed data acquisition system; and designing a development plan and constructing DASCAR. This report also covers: the background to the program; the requirements for the project; micro camera testing; heat load calculations for the DASCAR instrumentation package in automobile trunks; phase 2 of the research; the DASCAR hardware and software delivered to the National Highway Traffic Safety Administration; and crash avoidance problems that can be addressed by DASCAR.

  5. Listening, talking triumph in promoting effective public involvement

    SciTech Connect (OSTI)

    Forrest, C.J. [Equinox Environmental Consultants Ltd., Wheaton, IL (United States); Michaud, G.R. [Illinois Environmental Protection Agency`s, Springfield, IL (United States). Office of Community Relations

    1995-07-01

    When added to situations involving formal Superfund cleanups, RCRA permitting and other environmental issues, it is clear that understanding how to handle community concerns is rapidly becoming a necessity for many businesses. The terms public involvement, public participation and community relations all embody the same concept--establishing a dialogue with members of the public who are affected by environmental permitting, a contaminated site or other environmental issues. The goal of the dialogue is to promote public understanding about a project or issue, and ensure that citizens` concerns are considered and thoroughly addressed. Public concerns often are magnified by lack of information, misinformation or false information about an environmental issue. Failing to acknowledge concerns and provide appropriate information can lead to community resistance. In their extreme forms, such communications failures have slowed or blocked the permitting process, and even halted removal of hazardous wastes from residential and nonresidential areas. Community relations requirements under the Comprehensive Environmental Response, Compensation and Liability Act, and public participation requirements under the Resource Conservation and Recovery Act are intended to promote positive dialogue. In both cases, core activities and their timing are set by regulation.

  6. Exploring the Role of Positive Psychology Constructs as Protective Factors Against the Impact of Negative Environmental Variables on the Subjective Well-being of Older Adults 

    E-Print Network [OSTI]

    Pezent, Ginger Diane

    2011-08-08

    health status, lower social support, and negative life events (e.g., loss of spouse, reduced income, etc.). In this study, the subjective well-being in older adults is defined as an overall sense of satisfaction with life, high positive affect, and low...

  7. Involvement in Early Childhood Special Education Among Chinese and Non-Chinese American Parents

    E-Print Network [OSTI]

    SooHoo, Tanya

    2012-01-01

    in early childhood special education: Opportunities forInvolvement in Early Childhood Special Education AmongInvolvement in Early Childhood Special Education Among

  8. Product-Process Development Simulation to Support Specialty Contractor Involvement in Early Design

    E-Print Network [OSTI]

    Tommelein, Iris D.

    design of architecture-engineering-construction (AEC) products. Lean construction theory advocates such involvement. The practice of involving suppliers in product development and in manufacturing has proven

  9. File under: H Web name: Human Subjects, Policy on Research Involving [June 29, 2000] Official name: Policy on Research Involving Human Subjects [June 29, 2000] Location

    E-Print Network [OSTI]

    Prodiæ, Aleksandar

    File under: H Web name: Human Subjects, Policy on Research Involving [June 29, 2000] Official name: Policy on Research Involving Human Subjects [June 29, 2000] Location: https://share.utorcsi.utoronto.ca/sites/gc/Governing%20Council/All%20Policies/H/Human%20Subjects,%20Policy%20on%20Research %20Involving.docx [Official

  10. Boosting cooperation by involving extortion in spatial Prisoner's dilemma

    E-Print Network [OSTI]

    Wu, Zhi-Xi

    2014-01-01

    We study the evolution of cooperation in spatial Prisoner's dilemma games with and without extortion by adopting aspiration-driven strategy updating rule. We focus explicitly on how the strategy updating manner (whether synchronous or asynchronous) and also the introduction of extortion strategy affect the collective outcome of the games. By means of Monte Carlo (MC) simulations as well as dynamical cluster techniques, we find that the involvement of extortioners facilitates the boom of cooperators in the population (and whom can always dominate the population if the temptation to defect is not too large) for both synchronous and asynchronous strategy updating, in stark contrast to the otherwise case, where cooperation is promoted for intermediate aspiration level with synchronous strategy updating, but is remarkably inhibited if the strategy updating is implemented asynchronously. We explain the results by configurational analysis and find that the presence of extortion leads to the checkerboard-like orderin...

  11. Drivers of melanoma susceptibility

    E-Print Network [OSTI]

    Robles Espinoza, Carla Daniela

    2015-03-03

    (Winterstein A. Festschrift. Basel: Emil Barell; 1936; quoted by [83]), and subsequent experiments showed that BP applied on mouse skin, even at low doses, was highly carcinogenic and generally produced squamous cell carcinomas [84]. Other researchers were... caused by UV radiation . . . . . . . . . . . . . . 24 1.2 Paul Broca’s pedigree evidences familial predisposition to cancer . . . . . 26 1.3 Known melanoma susceptibility genes and their functions . . . . . . . . . 35 1.4 Polygenic model...

  12. Market Drivers for Biofuels

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    or natural gas, for process energy 6 Ethanol Grain Sorghum Dry mill process, using only biogas from landfills, waste treatment plants, andor waste digesters for process energy...

  13. The high current, fast, 100ns, Linear Transformer Driver (LTD) developmental project at Sandia Laboratories and HCEI.

    SciTech Connect (OSTI)

    Ward, Kevin S.; Long, Finis W.; Sinebryukhov, Vadim A. , Tomsk, Russia); Kim, Alexandre A. , Tomsk, Russia); Wakeland, Peter Eric; McKee, G. Randall; Woodworth, Joseph Ray; McDaniel, Dillon Heirman; Fowler, William E.; Mazarakis, Michael Gerrassimos; Porter, John Larry, Jr.; Struve, Kenneth William; Savage, Mark Edward; Stygar, William A.; LeChien, Keith R.; Matzen, Maurice Keith

    2010-09-01

    Sandia National Laboratories, Albuquerque, N.M., USA, in collaboration with the High Current Electronic Institute (HCEI), Tomsk, Russia, is developing a new paradigm in pulsed power technology: the Linear Transformer Driver (LTD) technology. This technological approach can provide very compact devices that can deliver very fast high current and high voltage pulses straight out of the cavity with out any complicated pulse forming and pulse compression network. Through multistage inductively insulated voltage adders, the output pulse, increased in voltage amplitude, can be applied directly to the load. The load may be a vacuum electron diode, a z-pinch wire array, a gas puff, a liner, an isentropic compression load (ICE) to study material behavior under very high magnetic fields, or a fusion energy (IFE) target. This is because the output pulse rise time and width can be easily tailored to the specific application needs. In this paper we briefly summarize the developmental work done in Sandia and HCEI during the last few years, and describe our new MYKONOS Sandia High Current LTD Laboratory. An extensive evaluation of the LTD technology is being performed at SNL and the High Current Electronic Institute (HCEI) in Tomsk Russia. Two types of High Current LTD cavities (LTD I-II, and 1-MA LTD) were constructed and tested individually and in a voltage adder configuration (1-MA cavity only). All cavities performed remarkably well and the experimental results are in full agreement with analytical and numerical calculation predictions. A two-cavity voltage adder is been assembled and currently undergoes evaluation. This is the first step towards the completion of the 10-cavity, 1-TW module. This MYKONOS voltage adder will be the first ever IVA built with a transmission line insulated with deionized water. The LTD II cavity renamed LTD III will serve as a test bed for evaluating a number of different types of switches, resistors, alternative capacitor configurations, cores and other cavity components. Experimental results will be presented at the Conference and in future publications.

  14. Optimizing and Diversifying the Electric Range of Plug-in Hybrid Electric Vehicles for U.S. Drivers

    SciTech Connect (OSTI)

    Lin, Zhenhong [ORNL

    2012-01-01

    To provide useful information for automakers to design successful plug-in hybrid electric vehicle (PHEV) products and for energy and environmental analysts to understand the social impact of PHEVs, this paper addresses the question of how many of the U.S. consumers, if buying a PHEV, would prefer what electric ranges. The Market-oriented Optimal Range for PHEV (MOR-PHEV) model is developed to optimize the PHEV electric range for each of 36,664 sampled individuals representing U.S. new vehicle drivers. The optimization objective is the minimization of the sum of costs on battery, gasoline, electricity and refueling hassle. Assuming no battery subsidy, the empirical results suggest that: 1) the optimal PHEV electric range approximates two thirds of one s typical daily driving distance in the near term, defined as $450/kWh battery delivered price and $4/gallon gasoline price. 2) PHEVs are not ready to directly compete with HEVs at today s situation, defined by the $600/kWh battery delivered price and the $3-$4/gallon gasoline price, but can do so in the near term. 3) PHEV10s will be favored by the market over longer-range PHEVs in the near term, but longer-range PHEVs can dominate the PHEV market if gasoline prices reach as high as $5-$6 per gallon and/or battery delivered prices reach as low as $150-$300/kWh. 4) PHEVs can become much more attractive against HEVs in the near term if the electric range can be extended by only 10% with multiple charges per day, possible with improved charging infrastructure or adapted charging behavior. 5) the impact of a $100/kWh decrease in battery delivered prices on the competiveness of PHEVs against HEVs can be offset by about $1.25/gallon decrease in gasoline prices, or about 7/kWh increase in electricity prices. This also means that the impact of a $1/gallon decrease in gasoline prices can be offset by about 5/kWh decrease in electricity prices.

  15. Representation of analysis results involving aleatory and epistemic uncertainty.

    SciTech Connect (OSTI)

    Johnson, Jay Dean; Helton, Jon Craig; Oberkampf, William Louis; Sallaberry, Cedric J.

    2008-08-01

    Procedures are described for the representation of results in analyses that involve both aleatory uncertainty and epistemic uncertainty, with aleatory uncertainty deriving from an inherent randomness in the behavior of the system under study and epistemic uncertainty deriving from a lack of knowledge about the appropriate values to use for quantities that are assumed to have fixed but poorly known values in the context of a specific study. Aleatory uncertainty is usually represented with probability and leads to cumulative distribution functions (CDFs) or complementary cumulative distribution functions (CCDFs) for analysis results of interest. Several mathematical structures are available for the representation of epistemic uncertainty, including interval analysis, possibility theory, evidence theory and probability theory. In the presence of epistemic uncertainty, there is not a single CDF or CCDF for a given analysis result. Rather, there is a family of CDFs and a corresponding family of CCDFs that derive from epistemic uncertainty and have an uncertainty structure that derives from the particular uncertainty structure (i.e., interval analysis, possibility theory, evidence theory, probability theory) used to represent epistemic uncertainty. Graphical formats for the representation of epistemic uncertainty in families of CDFs and CCDFs are investigated and presented for the indicated characterizations of epistemic uncertainty.

  16. Personnel involved in nuclear standards development: 1980 directory

    SciTech Connect (OSTI)

    Carr, S.J.

    1980-03-01

    The development of nuclear standards is an active and necessary endeavor that is concerned with the safe, orderly, and economic development of nuclear potential. There are almost 4100 people from the teachnical community who are presently involved either in writing nuclear standards, including codes, or in the management and processing roles necessary for their approval and promulgation. This document identifies the current participation of each individual as member, chairman, cochairman (vice-chairman), or secretary of about 700 standards development committees and groups. The standards committees and groups are identified with the organizations that are responsible for the preparation, review, and maintenance of the standards and that provide support through supervisory committees and headquarters staff. This directory includes four major sections: personnel, employers, committees, and a Key-Word-in-Context (KWIC) Index of committee titles. It can also be used to identify the participation of employers as well as to recognize the contributions of individuals to the often interdisciplinary activity of standards development.

  17. Department of Transportation I. Internal Scan

    E-Print Network [OSTI]

    Tipple, Brett

    Department of Transportation I. Internal Scan The number of older drivers in the United States-driver basis, older adults are among the safest. The average annual number of crashes in the United States million vehicle miles traveled (MVMT), drivers over the age of 75 have a fatality rate of 3.7 deaths per

  18. Quantitative understanding of Forbush decrease drivers based on shock-only and CME-only models using global signature of February 14, 1978 event

    SciTech Connect (OSTI)

    Raghav, Anil; Lotekar, Ajay; Bhaskar, Ankush; Vichare, Geeta; Yadav, Virendra E-mail: ankushbhaskar@gmail.com E-mail: vicharegeeta@gmail.com

    2014-10-01

    We have studied the Forbush decrease (FD) event that occurred on February 14, 1978 using 43 neutron monitor observatories to understand the global signature of FD. We have studied rigidity dependence of shock amplitude and total FD amplitude. We have found almost the same power law index for both shock phase amplitude and total FD amplitude. Local time variation of shock phase amplitude and maximum depression time of FD have been investigated which indicate possible effect of shock/CME orientation. We have analyzed rigidity dependence of time constants of two phase recovery. Time constants of slow component of recovery phase show rigidity dependence and imply possible effect of diffusion. Solar wind speed was observed to be well correlated with slow component of FD recovery phase. This indicates solar wind speed as possible driver of recovery phase. To investigate the contribution of interplanetary drivers, shock and CME in FD, we have used shock-only and CME-only models. We have applied these models separately to shock phase and main phase amplitudes respectively. This confirms presently accepted physical scenario that the first step of FD is due to propagating shock barrier and second step is due to flux rope of CME/magnetic cloud.

  19. Surface interactions involved in flashover with high density electronegative gases.

    SciTech Connect (OSTI)

    Hodge, Keith Conquest; Warne, Larry Kevin; Jorgenson, Roy Eberhardt; Wallace, Zachariah Red; Lehr, Jane Marie

    2010-01-01

    This report examines the interactions involved with flashover along a surface in high density electronegative gases. The focus is on fast ionization processes rather than the later time ionic drift or thermalization of the discharge. A kinetic simulation of the gas and surface is used to examine electron multiplication and includes gas collision, excitation and ionization, and attachment processes, gas photoionization and surface photoemission processes, as well as surface attachment. These rates are then used in a 1.5D fluid ionization wave (streamer) model to study streamer propagation with and without the surface in air and in SF6. The 1.5D model therefore includes rates for all these processes. To get a better estimate for the behavior of the radius we have studied radial expansion of the streamer in air and in SF6. The focus of the modeling is on voltage and field level changes (with and without a surface) rather than secondary effects, such as, velocities or changes in discharge path. An experiment has been set up to carry out measurements of threshold voltages, streamer velocities, and other discharge characteristics. This setup includes both electrical and photographic diagnostics (streak and framing cameras). We have observed little change in critical field levels (where avalanche multiplication sets in) in the gas alone versus with the surface. Comparisons between model calculations and experimental measurements are in agreement with this. We have examined streamer sustaining fields (field which maintains ionization wave propagation) in the gas and on the surface. Agreement of the gas levels with available literature is good and agreement between experiment and calculation is good also. Model calculations do not indicate much difference between the gas alone versus the surface levels. Experiments have identified differences in velocity between streamers on the surface and in the gas alone (the surface values being larger).

  20. SEER Forward Plan for 2013/2014 The SEER project involves understanding a number of natural and human systems which

    E-Print Network [OSTI]

    Bateman, Ian J.

    ; impacts upon water quality; impacts on carbon balance and greenhouse gas emissions; land use effects of natural and human systems which are related to changes to land use. These systems include the drivers bringing together natural and social science models. Methodological improvements in the valuation

  1. Classroom simulation of public involvement in H.L.W. issues featuring STS concepts

    SciTech Connect (OSTI)

    Bieniawski, Z.T.

    1996-12-01

    This paper reports on a classroom experiment, now in its third year, conducted by the author for students involvement in High-Level Waste disposal. The project involved designing a methodology for HLW management in the United States.

  2. Kindergarten Transition: Does family involvement make a difference in children's early school adjustment?

    E-Print Network [OSTI]

    Kang, Jean

    2010-07-30

    in kindergarten and the specific outcomes of family involvement is still very limited. Using a combination of quantitative and qualitative research methods, this study aims to investigate the impact of family involvement in kindergarten transition on children...

  3. Subbasin Planning Public Involvement Plan 1 Last Revised: 4/4/2004

    E-Print Network [OSTI]

    Subbasin Planning Public Involvement Plan 1 Last Revised: 4/4/2004 Walla Walla, Tucannon, Asotin & Lower Snake River Subbasin Planning Public Involvement Plan Background Public outreach and involvement is key to the success of the subbasin planning process. Without public acceptance and support of the plan

  4. SMALL AND LARGE-SCALE MAGNETIC FIELDS INVOLVED WITH SOLAR FLARES

    E-Print Network [OSTI]

    ABSTRACT SMALL AND LARGE-SCALE MAGNETIC FIELDS INVOLVED WITH SOLAR FLARES by Chang Liu Solar flares of an EUV sigmoid. #12;SMALL AND LARGE-SCALE MAGNETIC FIELDS INVOLVED WITH SOLAR FLARES by Chang Liu RESERVED #12;APPROVAL PAGE SMALL AND LARGE-SCALE MAGNETIC FIELDS INVOLVED WITH SOLAR FLARES Chang Liu Dr

  5. Nutrition for Older Adults. 

    E-Print Network [OSTI]

    Sweeten, Mary K.; Ryan-Crowe, V. Cass

    1982-01-01

    in too large a quanbty for one person. The market may be far away or hard to reach, especially in bad weather. These sug- gestions may help a pemn living alone: Plan carefully. Follow recipes so food is well prepared and not wasted. Try new dishes...

  6. A Polysilicon Active Matrix Organic Light Emitting Diode Display with Integrated Drivers R.M.A. Dawson, Z. Shen, D.A. Furst, S. Connor, J. Hsu, M.G. Kane, R.G. Stewart, A. Ipri

    E-Print Network [OSTI]

    A Polysilicon Active Matrix Organic Light Emitting Diode Display with Integrated Drivers R.S.A. Abstract The design of an active matrix organic light emitting diode (AMOLED) display using a polysilicon. Introduction Organic light emitting diodes (OLEDs) are presently of great interest due to their potential

  7. 2011 Regents of the University of Minnesota. All rights reserved. The University of Minnesota is an equal opportunity educator and employer. Segments of roads with LSFs (right) have better driver visibility and road surface

    E-Print Network [OSTI]

    Minnesota, University of

    and fewer accidents. LSFs can also benefit the atmosphere by storing carbon dioxide and reducing emissions is an equal opportunity educator and employer. Segments of roads with LSFs (right) have better driver visibility and road surface conditions than those without (left), leading to lower road maintenance costs

  8. Published in proceedings of the 15 th IMACS'97 World Congress, August 1997, Berlin, Germany, Wissenshaft & Technik Verlag, Vol. 4, pp. 571--576. The CTADEL Application Driver for Numerical Weather Forecast Systems

    E-Print Network [OSTI]

    van Engelen, Robert A.

    , Wissenshaft & Technik Verlag, Vol. 4, pp. 571--576. The CTADEL Application Driver for Numerical Weather@cs.leidenuniv.nl Keywords: code generation; high performance computing; numerical weather forecasting ABSTRACT The CTADEL numerical weather forecast system. As such, the CTADEL system can be viewed as a problem­solving environment

  9. A truck has a fuel tank which is a 20 inch diameter cylinder resting on its rounded side. The driver notices that his fuel gauge is no longer giving the correct readings, so he has to improvise. He places a

    E-Print Network [OSTI]

    Lega, Joceline

    A truck has a fuel tank which is a 20 inch diameter cylinder resting on its rounded side. The driver notices that his fuel gauge is no longer giving the correct readings, so he has to improvise. He to the bottom. He pulls the measuring stick out and finds that the height of the fuel is 6 inches. What fraction

  10. Perceptual and cognitive factors in legend legibility for large freeway guide signs 

    E-Print Network [OSTI]

    Kelly, Abbott Bowman

    1997-01-01

    Department of Transportation recently revised its design standards for freeway guide signs. These changes may have a significant impact on the ability of all drivers, but especially older drivers, to read and react to guide signs. This study explored ways...

  11. What is the effect of 4-H involvement on levels of empathy, self-esteem, community involvement and positive view of the future on urban youth? 

    E-Print Network [OSTI]

    Bonnett, Erika Dawn

    2007-04-25

    -1 WHAT IS THE EFFECT OF 4-H INVOLVEMENT ON LEVELS OF EMPATHY, SELF-ESTEEM, COMMUNITY INVOLVEMENT AND POSITIVE VIEW OF THE FUTURE ON URBAN YOUTH? A Thesis by ERIKA DAWN BONNETT Submitted to the Office of Graduate Studies of Texas A...-ESTEEM, COMMUNITY INVOLVEMENT AND POSITIVE VIEW OF THE FUTURE ON URBAN YOUTH? A Thesis by ERIKA DAWN BONNETT Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements for the degree of MASTER...

  12. Randomised controlled trial of the efficacy of aerobic exercise in reducing metabolic risk in healthy older people: The Hertfordshire Physical Activity Trial

    E-Print Network [OSTI]

    Finucane, Francis M.; Horton, Jessica; Purslow, Lisa R.; Savage, David B.; Brage, Søren; Besson, Herve; Horton, Kenneth; De Lucia Rolfe, Ema; Sleigh, Alison; Sharp, Stephen J.; Martin, Helen; Ahie Sayer, Avan; Cooper, Cyrus; Ekelund, Ulf; Griffin, Simon J.; Wareham, Nicholas J.

    2009-06-19

    affects the rela- tionship between muscle function and physical activity remains unknown. Methods/Design Study design This is a single centre, explanatory randomized controlled trial of the efficacy of a fully supervised twelve-week aero- bic exercise... five com- ponents of basic motor function in older people, namely dominant arm grip strength, time taken to rise from a chair and walk a short distance, repeated chair rises, cus- tomary walking speed and balance [55-57]. A sub-maxi- mal exercise test...

  13. 01-12-1998 - Bench Top FIre Involving Use of Alcohol and Burner...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    1998 - Bench Top FIre Involving Use of Alcohol and Burner Document Number: NA Effective Date: 011998 File (public): 01-12-1998...

  14. Molecular genetic analysis of activation-tagged transcription factors thought to be involved in photomorphogenesis

    SciTech Connect (OSTI)

    Neff, Michael M.

    2011-06-23

    This is a final report for Department of Energy Grant No. DE-FG02-08ER15927 entitled “Molecular Genetic Analysis of Activation-Tagged Transcription Factors Thought to be Involved in Photomorphogenesis”. Based on our preliminary photobiological and genetic analysis of the sob1-D mutant, we hypothesized that OBP3 is a transcription factor involved in both phytochrome and cryptochrome-mediated signal transduction. In addition, we hypothesized that OBP3 is involved in auxin signaling and root development. Based on our preliminary photobiological and genetic analysis of the sob2-D mutant, we also hypothesized that a related gene, LEP, is involved in hormone signaling and seedling development.

  15. Customer Involvement

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submit theCovalent Bonding inCustomer-Comments Sign In About |

  16. Getting Involved

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverse (Journalvivo Low-Dose Low LETUseful Links Useful Links:Get

  17. Breast Cancer Patients With 10 or More Involved Axillary Lymph Nodes Treated by Multimodality Therapy: Influence of Clinical Presentation on Outcome

    SciTech Connect (OSTI)

    Geara, Fady B. . E-mail: fg00@aub.edu.lb; Nasr, Elie; Tucker, Susan L.; Charafeddine, Maya; Dabaja, Bouthaina; Eid, Toufic; Abbas, Jaber; Salem, Ziad; Shamseddine, Ali; Issa, Philip; El Saghir, Nagi

    2007-06-01

    Purpose: To analyze tumor control and survival for breast cancer patients with 10 or more positive lymph nodes without systemic disease, treated by adjuvant radiation alone or combined-modality therapy. Methods and Materials: We reviewed the records of 309 consecutive patients with these characteristics who received locoregional radiotherapy (RT) at our institution. The majority of patients had clinical Stage II or IIIA-B disease (43% and 48%, respectively). The median number of positive axillary lymph nodes was 15 (range, 10-78). Adjuvant therapy consisted of RT alone, with or without chemotherapy, tamoxifen, and/or ovarian castration. Results: The overall 5-year and 10-year disease-free survival (DFS) rates were 20% and 7%, respectively. Median DFS was higher for patients with Stage I-II compared with those with Stage IIIABC (28 vs. 19 months; p = 0.006). Median DFS for patients aged {<=}35 years was lower than that of older patients (12 vs. 24 months; p < 0.0001). Patients treated with a combination therapy had a higher 5-year DFS rate compared with those treated by RT alone (26% vs. 11%; p 0.03). In multivariate analysis, clinical stage (III vs. I, II; relative risk = 1.8, p = 0.002) and age ({<=}35 vs. others; relative risk = 2.6, p <0.001) were found to be independent variables for DFS. Conclusion: This retrospective data analysis identified young age and advanced clinical stage as pertinent and independent clinical prognostic factors for breast cancer patients with advanced axillary disease (10 or more involved nodes). These factors can be used for further prognostic classification.

  18. Prefrontal involvement in the regulation of emotion: convergence of rat and human studies

    E-Print Network [OSTI]

    Quirk, Gregory J.

    experiments designed to bridge human and rodent models of emotion regulation. Addresses 1 Department of prefrontal involvement of emotion regula- tion using rat and human models, and suggest future experimentsPrefrontal involvement in the regulation of emotion: convergence of rat and human studies Gregory J

  19. Physical mechanisms involved in grooved flat heat pipes: experimental and numerical analyses

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    1 Physical mechanisms involved in grooved flat heat pipes: experimental and numerical analyses.lefevre@insa-lyon.fr) Abstract An experimental database, obtained with flat plate heat pipes (FPHP) with longitudinal grooves to results of numerical models. Physical mechanisms involved in grooved heat pipes are discussed, including

  20. Insensitizing controls for a heat equation with a nonlinear term involving the state and the

    E-Print Network [OSTI]

    González Burgos, Manuel

    Insensitizing controls for a heat equation with a nonlinear term involving the state In this paper we present two results on the existence of insensitizing controls for a heat equation in a bounded domain of IRN . We first consider a semilinear heat equation involving gradient terms with homogeneous

  1. Inclusion of Human Subjects in Research Human Subjects Involvement and Characteristics

    E-Print Network [OSTI]

    Firestone, Jeremy

    Inclusion of Human Subjects in Research Human Subjects Involvement and Characteristics: · Describe the proposed involvement of human subjects in the work outlined in the Research Design and Methods section. · Describe the characteristics of the subject population, including their anticipated number, age range

  2. Abstract--Many large scale system blackouts involve relay misoperations. Traditional relay algorithms and settings need to

    E-Print Network [OSTI]

    1 Abstract--Many large scale system blackouts involve relay misoperations. Traditional relay-wide blackouts involve relay misoperations [1]. Evaluation and improvement of existing relay algorithms

  3. Influence of microwave driver coupling design on plasma density at Testbench for Ion sources Plasma Studies, a 2.45 GHz Electron Cyclotron Resonance Plasma Reactor

    SciTech Connect (OSTI)

    Megía-Macías, A.; Vizcaíno-de-Julián, A. [E.S.S. Bilbao, Edificio Cosimet, Landabarri 2, 48940-Leioa, Vizcaya (Spain)] [E.S.S. Bilbao, Edificio Cosimet, Landabarri 2, 48940-Leioa, Vizcaya (Spain); Cortázar, O. D., E-mail: dcortazar@essbilbao.org [E.S.S. Bilbao, Edificio Cosimet, Landabarri 2, 48940-Leioa, Vizcaya (Spain); Universidad de Castilla-La Mancha, ETSII, C.J. Cela s/n, 13170 Ciudad Real (Spain)

    2014-03-15

    A comparative study of two microwave driver systems (preliminary and optimized) for a 2.45 GHz hydrogen Electron Cyclotron Resonance plasma generator has been conducted. The influence on plasma behavior and parameters of stationary electric field distribution in vacuum, i.e., just before breakdown, along all the microwave excitation system is analyzed. 3D simulations of resonant stationary electric field distributions, 2D simulations of external magnetic field mapping, experimental measurements of incoming and reflected power, and electron temperature and density along the plasma chamber axis have been carried out. By using these tools, an optimized set of plasma chamber and microwave coupler has been designed paying special attention to the optimization of stationary electric field value in the center of the plasma chamber. This system shows a strong stability on plasma behavior allowing a wider range of operational parameters and even sustaining low density plasma formation without external magnetic field. In addition, the optimized system shows the capability to produce values of plasma density four times higher than the preliminary as a consequence of a deeper penetration of the magnetic resonance surface in relative high electric field zone by keeping plasma stability. The increment of the amount of resonance surface embedded in the plasma under high electric field is suggested as a key factor.

  4. Undergraduate business and management students’ experiences of being involved in assessment 

    E-Print Network [OSTI]

    Tai, Chunming

    2012-11-29

    This study aimed to explore university undergraduates’ experiences of student involvement in assessment (SIA). Based on Biggs’ 3P model of student learning, this study focused on students’ experiences prior to SIA, during ...

  5. The interactive effects of individual learning style, computer software, and teacher involvement on developing typing skill 

    E-Print Network [OSTI]

    Goodman, Sarina Renae

    1995-01-01

    This research examines the effects and interactions of an individual's learning style, the type of computer software, and the level of teacher involvement on students learning how to type on a computer keyboard. The research ...

  6. Removing the HUD: The Impact of Non-Diegetic Game Elements and Expertise on Player Involvement

    E-Print Network [OSTI]

    Cairns, Paul

    Removing the HUD: The Impact of Non-Diegetic Game Elements and Expertise on Player Involvement-character can see and interact with; and the latter does not, e.g. classic heads-up displays (HUDs) showing

  7. Examination of offsite radiological emergency protective measures for nuclear reactor accidents involving core melt

    E-Print Network [OSTI]

    Aldrich, David C.

    1979-01-01

    Evacuation, sheltering followed by population relocation, and iodine prophylaxis are evaluated as offsite public protective measures in response to nuclear reactor accidents involving core-melt. Evaluations were conducted ...

  8. The obligation nation : America's involvement in the affairs of the World

    E-Print Network [OSTI]

    Francel, Leif (Leif G.)

    2012-01-01

    Does America have an obligation, whether through foreign aid, military involvement, or by spreading democracy, to change the world? This thesis answers these above questions in intimate detail through the moral framework ...

  9. Cold shock response of Salmonella enterica serovar typhimurium; the involvement of the CspA paralogues 

    E-Print Network [OSTI]

    Woodall, Katy Anna

    2011-11-24

    Salmonella enterica sv. typhimurium is a major food-borne pathogen, in part because of its ability to persist and multiply at low temperatures. Adaptation to refrigerated temperatures involves induction of a multigenic ...

  10. School-Based Family Involvement: Patterns and Predictors in the NLTS2 

    E-Print Network [OSTI]

    Frew, Leigh Ann

    2012-10-19

    This investigation used data from the National Longitudinal Transition Study 2 (NLTS2) to investigate patterns among student, family, and school characteristics, school outreach programs, and school-based family involvement for families of 5...

  11. A study of parental involvement and school climate: Perspective from the middle school 

    E-Print Network [OSTI]

    Dixon, Shantina Rayford

    2009-05-15

    This study examines school level differences on different dimensions of teacherrated parent involvement and school climate while adjusting for age, gender, ethnicity, how certified, and number of years teaching. Two hundred twenty-four elementary...

  12. Offline Memory Reprocessing: Involvement of the Brain's Default Network in Spontaneous Thought Processes

    E-Print Network [OSTI]

    Jiang,Tianzi

    Offline Memory Reprocessing: Involvement of the Brain's Default Network in Spontaneous Thought active during the task-free state. Interestingly, we found that offline reprocessing of previously integration and functional separation among its component regions to execute offline memory reprocessing

  13. Study of instability formation and EUV emission in thin liners driven with a compact 250?kA, 150?ns linear transformer driver

    SciTech Connect (OSTI)

    Valenzuela, J. C., E-mail: jcval@ucsd.edu; Collins, G. W.; Mariscal, D.; Beg, F. N. [Center for Energy Research, University of California San Diego, La Jolla, California 92093 (United States)] [Center for Energy Research, University of California San Diego, La Jolla, California 92093 (United States); Wyndham, E. S. [Facultad de Física, Pontificia Universidad Católica de Chile, Ave. Vicuña Mackena 4860, Macul, Santiago (Chile)] [Facultad de Física, Pontificia Universidad Católica de Chile, Ave. Vicuña Mackena 4860, Macul, Santiago (Chile)

    2014-03-15

    A compact linear transformer driver, capable of producing 250?kA in 150?ns, was used to study instability formation on the surface of thin liners. In the experiments, two different materials, Cu and Ni, were used to study the effect of the liner's resistivity on formation and evolution of the instabilities. The dimensions of the liners used were 7?mm height, 1?mm radius, and 3??m thickness. Laser probing and time resolved extreme ultraviolet (EUV) imaging were implemented to diagnose instability formation and growth. Time-integrated EUV spectroscopy was used to study plasma temperature and density. A constant expansion rate for the liners was observed, with similar values for both materials. Noticeable differences were found between the Cu and Ni instability growth rates. The most significant perturbation in Cu rapidly grows and saturates reaching a limiting wavelength of the order of the liner radius, while the most significant wavelength in Ni increases slowly before saturating, also at a wavelength close to the liner radius. Evidence suggests that the instability observed is the well-known m?=?0 MHD instability. However, upon comparing the instability evolution of Cu and Ni, the importance of the resistivity on the seeding mechanism becomes evident. A comparison of end-on and side-on EUV emission possible indicates the formation of precursor plasma, where it has been estimated using EUV spectroscopy that the precursor plasma temperature is approximately 40?eV with ion density of order 10{sup 19}?cm{sup ?3}, for both materials.

  14. Disability and Suicidal Ideation in Older Prisoners: A Pilot Study Lisa C. Barry, PhD, MPH1; Robert L. Trestman, PhD, MD2; Yeates Conwell, MD3

    E-Print Network [OSTI]

    Oliver, Douglas L.

    disability in prison-ADLs (PADLs), such as climbing on and off the top bunk and walking to the dining hallDisability and Suicidal Ideation in Older Prisoners: A Pilot Study Lisa C. Barry, PhD, MPH1; Robert for current suicidal ideation (SI), emphasizing deficits in functional abilities specific to the prison

  15. The cost of public involvement lessons learned: How we can reinvest in the future

    SciTech Connect (OSTI)

    Baranski, S.C. [Equinox Environmental, Inc., Shushan, NY (United States); McMullin, K.M. [Equinox Environmental, Inc., Ballston Spa, NY (United States)

    1996-12-31

    Throughout the history of environmental remediation and restoration projects, education programs have been viewed as something to develop when the financial climate is good, and something to eliminate when the financial picture declines. Technology and risk are issues that citizens and interested community members have come to be concerned about regardless of the purpose of the project. Many times the public response to an environmental remediation effort is unanticipated. Government and industry representatives often forget that even a {open_quotes}cleanup{close_quotes} effort can cause unrest in a community. Past education and public involvement efforts have been costly, from both a financial perspective and from a public policy and programmatic perspective. Money alone cannot provide education and public involvement opportunities that will enable a project to go forward to completion. Investment in environmental programs and projects for education, public involvement and communication activities has been substantial, from a financial point of view. Investment, from a policy and program success perspective, has not yielded high returns on the investment. One must examine past and current education and public involvement {open_quotes}investments{close_quotes} and where emphasis has been place in development of the programs. In this review, the authors suggest the need to look at the level of investment from the following perspectives: (1) Financial, (2) Educational Opportunity, (3) Public Involvement Opportunity, (4) Policy and Programmatic Success, (5) Evaluation of Cost and Resulting Benefit, and (6) Reinvesting Our Financial Commitments for the Future.

  16. The Community Environmental Monitoring Program: Reducing Public Perception of Risk through Stakeholder Involvement

    SciTech Connect (OSTI)

    William T. Hartwell

    2007-05-21

    The Community Environmental Monitoring Program (CEMP) has promoted stakeholder involvement, awareness, and understanding of radiological surveillance in communities surrounding the Nevada Test Site (NTS) since 1981. It involves stakeholders in the operation, data collection, and dissemination of information obtained from a network of 29 stations across a wide area of Nevada, Utah and California. It is sponsored by the U.S. Department of Energy, National Nuclear Security Administration’s Nevada Site Office (NNSA/NSO) and administered by the Desert Research Institute (DRI) of the Nevada System of Higher Education. Integration of a near real-time communications system, a public web site, training workshops for involved stakeholders, and educational programs all help to alleviate public perception of risk of health effects from past activities conducted at the NTS.

  17. Proposed Tenaska Washington II Generation Project : Final Environmental Impact Statement. Volume 2: Public Involvement.

    SciTech Connect (OSTI)

    United States. Bonneville Power Administration.

    1994-01-01

    In regard to the proposed Tenaska Washington II Generation Project, the goal of the Bonneville Power Administration`s (BPA) Environmental Impact Statement (EIS) public involvement process is to determine the issues to be examined and pertinent analyses to be conducted and to solicit comments on the content and quality of information presented in the Draft Environmental Impact Statement (DEIS). Comments and questions are solicited from the public and government agencies during the scoping process and during the comment period and public hearing on the DEIS, to find out what is of most concern to them. The end product of the public involvement process is the Comment Report which follows in part of this volume on Public Involvement.

  18. Getting the lead out: Citizen involvement in the Williamsburg Bridge lead paint removal project

    SciTech Connect (OSTI)

    Forker, T.R.

    1997-08-01

    This paper examines the process and results of citizen involvement in developing new environmental control and compliance procedures used by the New York City Department of Transportation (NYC DOT) for lead paint removal on the Williamsburg Bridge and other structures. As a case study of the effects of public involvement in environmental decision-making, the study identifies and discusses the factors that produced failures or successes in satisfying the citizen`s concerns about health risks and the effectiveness of the selected pollution control technology.

  19. Driver Safety Training Facilities Management's

    E-Print Network [OSTI]

    Soerens, Thomas

    order Check gauges- be sure fuel, oil, battery, and temperature are normal (with motor running) Report as you approach bridges and overpasses in the winter. These sections freeze first and stay frozen long seatbelt. Always look out for pedestrians. Obey traffic signals/signs/laws. Do not use your cell phone

  20. P5 Science Drivers: Theory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration wouldMass mapSpeeding access toOctoberConsumptionPowered oscillator usingLow Risk (Rev 5,Science

  1. Regulatory Drivers | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustmentsShirleyEnergy AEnergyPresidentialThis 3-DMarch 9, 2015Watchdog | Department ofStatutes and

  2. Mechanistic Studies on the Radical S-Adenosylmethionine Enzymes Involved in Molybdopterin, Thiamin and Vitamin B12 Biosynthesis 

    E-Print Network [OSTI]

    Mehta, Angad P

    2015-02-09

    ) hydroxybenzimidazole synthase, HBI synthase, involved in anaerobic vitamin B12 biosynthesis. MoaA catalyzes the first step in molydopterin biosynthesis where GTP is converted to pterin. This catalysis involves a remarkable rearrangement reaction where the C8...

  3. The EMBO Journal vol. 13 no. 1 1 pp.2592 -2599, 1994 Genetic and molecular analyses of mutations involved in

    E-Print Network [OSTI]

    Higgins, Darren

    involved in Drosophila raf signal transduction Xiangyi Lu, Michael B.Melnick, Jui-Chou Hsu and Norbert

  4. Are teens safer on the road than they were ten years ago? Yes, and no

    E-Print Network [OSTI]

    relative to that of young adult drivers (18 to 24 years old) when drivers in each group are accompanied population. (1) Novice drivers (15 to 17 years old) are at a distinct disadvantage, not only because to fatal crashes involving young adult drivers. From 2002 to 2011, the number of drivers aged 15 to 17

  5. Distributional properties of Euclidean distances in wireless networks involving road systems

    E-Print Network [OSTI]

    Schmidt, Volker

    1 Distributional properties of Euclidean distances in wireless networks involving road systems of large wireless networks. The network geometry is modelled by random geometric graphs, and the locations are closely related with the interference geometry and, consequently, the performance of wireless networks

  6. INVOLVEMENT OF THE FGFR4 Arg388 ALLELE IN HEAD AND NECK SQUAMOUS CELL CARCINOMA

    E-Print Network [OSTI]

    Ullrich, Axel

    INVOLVEMENT OF THE FGFR4 Arg388 ALLELE IN HEAD AND NECK SQUAMOUS CELL CARCINOMA Sylvia STREIT 1/Arg polymorphism (388) in head and neck squamous cell carcinomas (HNSCCs) of the oral cavity and the oropharynx and graded into a low, intermediate, or high degree of staining. FGFR4 expression was scored as high in 17

  7. Sensor applications have now touched onto the realms of real-time data processing involving

    E-Print Network [OSTI]

    Najjar, Walid A.

    sensing needs, coupled with an interface integrating up to gigabyte scale energy efficient data storage sound / voice samples. Such applications demand real time storage, filtering, frequency domain analysis involving algorithms as sophisticated as Fast Fourier Transform (FFT), Finite Impulse Response (FIR

  8. The Penrose inequality in general relativity and volume comparison theorems involving scalar curvature (thesis)

    E-Print Network [OSTI]

    Hubert L. Bray

    2009-02-18

    In this thesis we describe how minimal surface techniques can be used to prove the Penrose inequality in general relativity for two classes of 3-manifolds. We also describe how a new volume comparison theorem involving scalar curvature for 3-manifolds follows from these same techniques.

  9. Computationally efficient parabolic equation solutions to seismo-acoustic problems involving

    E-Print Network [OSTI]

    Computationally efficient parabolic equation solutions to seismo-acoustic problems involving thin converged solutions. In this paper, a seismo-acoustic parabolic equation solution is derived utilizing require finer grids to fully sample effects due to elasticity within the layer. As shear wave speeds

  10. [21] FusionBased Strategies to Identify Genes Involved in Degradation of a Specific Substrate

    E-Print Network [OSTI]

    Hampton, Randy

    [21] FusionBased Strategies to Identify Genes Involved in Degradation of a Specific Substrate By RANDOLPH Y. HAMPTON Abstract Fusion proteins have been used in many instances to allow genetic screening Principles of Using Fusion Reporters to Discover Degradation Genes Because protein degradation is highly

  11. Arabidopsis genomes uncoupled 5 (GUN5) mutant reveals the involvement of Mg-chelatase H subunit

    E-Print Network [OSTI]

    Brusslan, Judy

    Arabidopsis genomes uncoupled 5 (GUN5) mutant reveals the involvement of Mg-chelatase H subunit nuclear- and chloroplast-localized genes that encode photosynthesis-related proteins. Arabidopsis GUN (ge. Unlike wild-type plants, gun mutants have nuclear Lhcb1 expression in the absence of chloroplast

  12. Local Involvement in Measuring and Governing Carbon Stocks in China, Vietnam, Indonesia and Laos

    E-Print Network [OSTI]

    26 Local Involvement in Measuring and Governing Carbon Stocks in China, Vietnam, Indonesia and Laos-REDD+ study sites in China, Vietnam, Indonesia and Laos have been trained in establishing vegetation plots in China, Indonesia, Lao PDR and Vietnam from 2011 to 2014. ___________________________ 1 Skindergade 23

  13. Parabolic equation solution of seismo-acoustics problems involving variations in bathymetry and sediment thickness

    E-Print Network [OSTI]

    and sediment thickness Jon M. Collisa and William L. Siegmann Rensselaer Polytechnic Institute110 8th Street within elastic sediment layers. When these methods are implemented together, the parabolic equation method can be applied to problems involving variations in bathymetry and the thickness of sediment layers

  14. Response to Xanthomonas campestris pv. vesicatoria in Tomato Involves Regulation of Ethylene Receptor

    E-Print Network [OSTI]

    Klee, Harry J.

    Response to Xanthomonas campestris pv. vesicatoria in Tomato Involves Regulation of Ethylene ethylene's role in plant response to virulent and avirulent strains of Xanthomonas campestris pv overexpressing a wild-type NR cDNA were infected with virulent X. campestris pv. vesicatoria. Like the Nr mutant

  15. Emergency Action Plan For incidents involving hazardous materials, fires, explosions, or natural gas

    E-Print Network [OSTI]

    Mojzsis, Stephen J.

    -492-6025. For Non-Emergency Fire and Natural Gas Questions call the CU Fire Marshall @ 303-492-4042. AdditionalEmergency Action Plan For incidents involving hazardous materials, fires, explosions, or natural gas leaks, the following actions should be taken: 1) Life Safety First 2) Evacuate Immediate Area 3

  16. Marketing involves the design, pricing, promotion and distribution of goods and services for consumers.

    E-Print Network [OSTI]

    5/2013 MARKETING Marketing involves the design, pricing, promotion and distribution of goods marketing's critical role in analyzing consumer needs and the importance of securing information designed and services for consumers. Marketing encompasses consumer behavior, retail business site selection, store

  17. Final report on the public involvement process phase 1, Monitored Retrievable Storage Facility Feasibility Study

    SciTech Connect (OSTI)

    Moore, L.; Shanteau, C.

    1992-12-01

    This report summarizes the pubic involvement component of Phase 1 of the Monitored Retrievable Storage Facility (NM) Feasibility Study in San Juan County, Utah. Part of this summary includes background information on the federal effort to locate a voluntary site for temporary storage of nuclear waste, how San Juan County came to be involved, and a profile of the county. The heart of the report, however, summarizes the activities within the public involvement process, and the issues raised in those various forums. The authors have made every effort to reflect accurately and thoroughly all the concerns and suggestions expressed to us during the five month process. We hope that this report itself is a successful model of partnership with the citizens of the county -- the same kind of partnership the county is seeking to develop with its constituents. Finally, this report offers some suggestions to both county officials and residents alike. These suggestions concern how decision-making about the county's future can be done by a partnership of informed citizens and listening decision-makers. In the Appendix are materials relating to the public involvement process in San Juan County.

  18. Final report on the public involvement process phase 1, Monitored Retrievable Storage Facility Feasibility Study

    SciTech Connect (OSTI)

    Moore, L.; Shanteau, C.

    1992-12-01

    This report summarizes the pubic involvement component of Phase 1 of the Monitored Retrievable Storage Facility (NM) Feasibility Study in San Juan County, Utah. Part of this summary includes background information on the federal effort to locate a voluntary site for temporary storage of nuclear waste, how San Juan County came to be involved, and a profile of the county. The heart of the report, however, summarizes the activities within the public involvement process, and the issues raised in those various forums. The authors have made every effort to reflect accurately and thoroughly all the concerns and suggestions expressed to us during the five month process. We hope that this report itself is a successful model of partnership with the citizens of the county -- the same kind of partnership the county is seeking to develop with its constituents. Finally, this report offers some suggestions to both county officials and residents alike. These suggestions concern how decision-making about the county`s future can be done by a partnership of informed citizens and listening decision-makers. In the Appendix are materials relating to the public involvement process in San Juan County.

  19. Electronic spectroscopy of intermediates involved in the conversion of methane to methanol by FeO

    E-Print Network [OSTI]

    Metz, Ricardo B.

    Electronic spectroscopy of intermediates involved in the conversion of methane to methanol by Fe.1063/1.1448489 I. INTRODUCTION The direct oxidation of methane to an easily transport- able liquid such as methanol process and as the simplest model for alkane oxidation.1,2 Although no direct, efficient methane­methanol

  20. Study: Among Street-Involved Youth, Women Twice as Likely to be Infected with Hepatitis C

    E-Print Network [OSTI]

    Kavanagh, Karen L.

    Study: Among Street-Involved Youth, Women Twice as Likely to be Infected with Hepatitis C Vancouver the hepatitis C virus (HCV), according to a new study by the BC Centre for Excellence in HIV/AIDS (BC surveillance data, on a national scale, men have higher rates of hepatitis C diagnosis than women (36.8 per 100

  1. Planning for multiple mobile robots in dynamic environ ments involves determining the optimal path each robot

    E-Print Network [OSTI]

    Stentz, Tony

    Abstract Planning for multiple mobile robots in dynamic environ­ ments involves determining the optimal path each robot should follow to accomplish the goals of the mission, given the current knowledge reassign robots to goals in order to continually minimize the time to complete the mission. In this paper

  2. On the Cover: One route to harvesting the energy of the sun involves learning to mimic

    E-Print Network [OSTI]

    Wu, Zhigang

    #12;On the Cover: One route to harvesting the energy of the sun involves learning to mimic natural the chlorophylls, which play a central role in capturing light and using its energy for photosynthesis in green, and atmospheric carbon dioxide. #12;BASIC RESEARCH NEEDS FOR SOLAR ENERGY UTILIZATION Report on the Basic Energy

  3. Differing Professional Opinions Manual for Technical Issues Involving Environment, Safety, and Health

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2006-11-16

    This Manual establishes a differing professional opinion (DPO) policy to a Department of Energy (DOE) Differing Professional Opinion (DPO) Process to encourage and facilitate dialogue and resolution on DPOs from employees for technical issues involving environment, safety, and health. Does not cancel other directives. Canceled by DOE O 442.2.

  4. Quantitative traits loci (QTL) involved in body colour, wing morphometry, cuticular hydrocarbons

    E-Print Network [OSTI]

    Quantitative traits loci (QTL) involved in body colour, wing morphometry, cuticular hydrocarbons for wing morphometry, 12 for cuticular hydrocarbons and five for venom components. We detected 50 QTL / cuticular hydrocarbons / venom 1. INTRODUCTION The first genetic map built from RAPD markers (Hunt and Page

  5. Statistical Issues in the Study of Air Pollution Involving Airborne Particulate Matter

    E-Print Network [OSTI]

    Washington at Seattle, University of

    Statistical Issues in the Study of Air Pollution Involving Airborne Particulate Matter Lawrence H which provides the Center's primary funding. #12;1 STATISTICAL ISSUES IN THE STUDY OF AIR POLLUTION.S. cities. This and other scientific and policy information formed the basis on which the U.S. Environmental

  6. A ash-drag effect in random motion reveals involvement of preattentive motion processing

    E-Print Network [OSTI]

    Whitney, David

    A ash-drag effect in random motion reveals involvement of preattentive motion processing Department-ku, Tokyo, JapanIkuya Murakami The ash-drag (FDE) effect refers to the phenomenon in which the position of a stationary ashed object in one location appears shifted in the direction of nearby motion. Over the past

  7. Real and padic expansions involving symmetric patterns Boris ADAMCZEWSKI & Yann BUGEAUD

    E-Print Network [OSTI]

    Bugeaud, Yann

    , and by questions related to the expected normality of irrational algebraic numbers. We introduce a class symmetric patterns. Then, we prove several transcendence statements involving both real and p­adic numbers) expansion of irrational algebraic real (resp. p­adic) numbers. Moreover, it is expected that these numbers

  8. 3280 J. Am. Chem. Soc. 1982, 104, 3280-3287 Energetics and Mechanisms for Reactions Involving

    E-Print Network [OSTI]

    Goddard III, William A.

    is thought4 to involve several of species I-IX. In addition, thermochemical studies of I-IX provide limited thermochemical data are available. Several ab initio calculations on N2H20isomers have previously ;>N-N- 37.6 35.4 3.0 IX Table 11. Relative Enthalpies (at 298 K) Useful in AnalyzingReaction 57 NH

  9. The involvement of recurrent connections in area CA3 in establishing the properties of place elds

    E-Print Network [OSTI]

    Dayan, Peter

    The involvement of recurrent connections in area CA3 in establishing the properties of place #12 model of CA3 place #12;elds 51 text pages, 12 #12;gures, 1 table 206 words in abstract, 474- tions. We describe an attractor network model of area CA3 in which local, recurrent, excitatory

  10. Introduction Animals must feed to survive, but foraging often involves a

    E-Print Network [OSTI]

    Sokolowski, Marla

    from predators, parasites, exhaustion or toxins, for example. Many risk-mitigation adaptations, which., 2006). Within a species, individuals may exhibit polymorphic and/or plastic responses to fluctuating food availability. Naturally varying genes involved in plastic responses to changes in food

  11. The Case for APICS Involvement with Auto-ID Technology Edmund W. Schuster

    E-Print Network [OSTI]

    Brock, David

    members. The establishment of industry standards for the Universal Product Code (UPC) is a major reason so many organizations belong to the UCC. Though APICS is not in a position to develop industry standards of the reason traces to a historical lack of involvement from the food industry in society matters

  12. RNS and Pure Spinors Equivalence for Type I Tree Level Amplitudes Involving up to Four Fermions

    E-Print Network [OSTI]

    G. Alencar; M. O. Tahim; R. R. Landim; R. N. Costa Filho

    2011-11-25

    In this paper we give a proof of the equivalence between the RNS and Pure Spinor formalism for Type I tree level amplitudes involving up to four fermions. This result have been obtained previously for amplitudes involving only closed or open amplitudes and here we extend it to include Type I amplitudes. For this we first prove the cyclic symmetry of Type I superstring in a way that it is also valid for the Pure Spinor formalism. The technique used is applied to simplify the calculation of the tree level three point amplitude previously computed. As a byproduct, we are able to calculate the gauge anomaly amplitude of type I Superstrings in this formalism.

  13. Multicolor Ramsey Numbers Involving K3 + e and K4 -e

    E-Print Network [OSTI]

    Radziszowski, Stanislaw P.

    On Some Multicolor Ramsey Numbers Involving K3 + e and K4 - e Daniel S. Shetler Department: The Ramsey number R(G1, G2, G3) is the smallest positive in- teger n such that for all 3-colorings color. We study the bounds on various 3-color Ramsey numbers R(G1, G2, G3), where Gi {K3, K3 + e, K4

  14. TEC protein tyrosine kinase is involved in the Erk signaling pathway induced by HGF

    SciTech Connect (OSTI)

    Li, Feifei; Jiang, Yinan [Department of Pathophysiology, Anhui Medical University, Hefei 230032 (China)] [Department of Pathophysiology, Anhui Medical University, Hefei 230032 (China); Zheng, Qiping [Department of Anatomy and Cell Biology, Rush University Medical Center, Chicago, IL 60612 (United States)] [Department of Anatomy and Cell Biology, Rush University Medical Center, Chicago, IL 60612 (United States); Yang, Xiaoming [Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850 (China)] [Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850 (China); Wang, Siying, E-mail: sywang@ahmu.edu.cn [Department of Pathophysiology, Anhui Medical University, Hefei 230032 (China)] [Department of Pathophysiology, Anhui Medical University, Hefei 230032 (China)

    2011-01-07

    Research highlights: {yields} TEC is rapidly tyrosine-phosphorylated and activated by HGF-stimulation in vivo or after partial hepatectomy in mice. {yields} TEC enhances the activity of Elk and serum response element (SRE) in HGF signaling pathway in hepatocyte. {yields} TEC promotes hepatocyte proliferation through the Erk-MAPK pathway. -- Abstract: Background/aims: TEC, a member of the TEC family of non-receptor type protein tyrosine kinases, has recently been suggested to play a role in hepatocyte proliferation and liver regeneration. This study aims to investigate the putative mechanisms of TEC kinase regulation of hepatocyte differentiation, i.e. to explore which signaling pathway TEC is involved in, and how TEC is activated in hepatocyte after hepatectomy and hepatocyte growth factor (HGF) stimulation. Methods: We performed immunoprecipitation (IP) and immunoblotting (IB) to examine TEC tyrosine phosphorylation after partial hepatectomy in mice and HGF stimulation in WB F-344 hepatic cells. The TEC kinase activity was determined by in vitro kinase assay. Reporter gene assay, antisense oligonucleotide and TEC dominant negative mutant (TEC{sup KM}) were used to examine the possible signaling pathways in which TEC is involved. The cell proliferation rate was evaluated by {sup 3}H-TdR incorporation. Results: TEC phosphorylation and kinase activity were increased in 1 h after hepatectomy or HGF treatment. TEC enhanced the activity of Elk and serum response element (SRE). Inhibition of MEK1 suppressed TEC phosphorylation. Blocking TEC activity dramatically decreased the activation of Erk. Reduced TEC kinase activity also suppressed the proliferation of WB F-344 cells. These results suggest TEC is involved in the Ras-MAPK pathway and acts between MEK1 and Erk. Conclusions: TEC promotes hepatocyte proliferation and regeneration and is involved in HGF-induced Erk signaling pathway.

  15. Deuteron stripping and pickup involving halo nuclei 11Be and 15C

    E-Print Network [OSTI]

    A. Deltuva

    2009-04-22

    Three-body calculations of (d,p) and (p,d) reactions involving one-neutron halo nuclei 11Be and 15C are performed using the framework of Faddeev-type scattering equations. Important effects of the optical potential nonlocality are found improving the description of the experimental data. The obtained values for the neutron spectroscopic factor are consistent with estimations from other approaches.

  16. Spatial arrangement of trail markers and visitor involvement on a self-guided interpretive trail 

    E-Print Network [OSTI]

    Marcy, Julie Benedict

    1982-01-01

    be presented by asking "what constitutes an effective SGT in terms of visitor involvement with t'ne trail, leaflet suggestions, and the spacing of stakes or markers on the trail?" An effecrive program or technique is one which achieves its desired... concluded with open-ended questions on suggested improvements for the trail and leaflet. Sontag (27) states rhat there are three main ccmponents of t. rail evaluation: personal objeccive evaluation, observing visitor reaction, and questionnaires...

  17. Temperature of aircraft cargo flame exposure during accidents involving fuel spills

    SciTech Connect (OSTI)

    Mansfield, J.A.

    1993-01-01

    This report describes an evaluation of flame exposure temperatures of weapons contained in alert (parked) bombers due to accidents that involve aircraft fuel fires. The evaluation includes two types of accident, collisions into an alert aircraft by an aircraft that is on landing or take-off, and engine start accidents. Both the B-1B and B-52 alert aircraft are included in the evaluation.

  18. 35.1 Introduction Flows.involving.phase.change.are.ubiquitous.in.geophysical.and.

    E-Print Network [OSTI]

    Huppert, Herbert

    467 35.1 Introduction Flows.involving.phase.change.are.ubiquitous.in.geophysical.and. industrial.and.atmosphere.but.also.some.that.occur.in.water- saturated.soils,.in.magmatic.systems,.and.in.industrial.processes. 35.2 Principles Changes.of.phase,.from.and.associated.buoyancy.forces..The.importance.of.phase. change.to.a.given.flow.can.be.assessed.by.estimating.certain.key. dimensionless.parameters. 35

  19. Involvement of HIF-2?-mediated inflammation in arsenite-induced transformation of human bronchial epithelial cells

    SciTech Connect (OSTI)

    Xu, Yuan; Zhao, Yue; Xu, Wenchao; Luo, Fei; Wang, Bairu; Li, Yuan; Pang, Ying; Liu, Qizhan, E-mail: drqzliu@hotmail.com

    2013-10-15

    Arsenic is a well established human carcinogen that causes diseases of the lung. Some studies have suggested a link between inflammation and lung cancer; however, it is unknown if arsenite-induced inflammation causally contributes to arsenite-caused malignant transformation of cells. In this study, we investigated the molecular mechanisms underlying inflammation during neoplastic transformation induced in human bronchial epithelial (HBE) cells by chronic exposure to arsenite. The results showed that, on acute or chronic exposure to arsenite, HBE cells over-expressed the pro-inflammatory cytokines, interleukin-6 (IL-6), interleukin-8 (IL-8), and interleukin-1? (IL-1?). The data also indicated that HIF-2? was involved in arsenite-induced inflammation. Moreover, IL-6 and IL-8 were essential for the malignant progression of arsenite-transformed HBE cells. Thus, these experiments show that HIF-2? mediates arsenite-induced inflammation and that such inflammation is involved in arsenite-induced malignant transformation of HBE cells. The results provide a link between the inflammatory response and the acquisition of a malignant transformed phenotype by cells chronically exposed to arsenite and thus establish a previously unknown mechanism for arsenite-induced carcinogenesis. - Highlights: • Arsenite induces inflammation. • Arsenite-induced the increases of IL-6 and IL-8 via HIF-2?. • Inflammation is involved in arsenite-induced carcinogenesis.

  20. Quality control procedures for dynamic treatment delivery techniques involving couch motion

    SciTech Connect (OSTI)

    Yu, Victoria Y.; Fahimian, Benjamin P.; Xing, Lei; Hristov, Dimitre H.

    2014-08-15

    In this study, the authors introduce and demonstrate quality control procedures for evaluating the geometric and dosimetric fidelity of dynamic treatment delivery techniques involving treatment couch motion synchronous with gantry and multileaf collimator (MLC). Tests were designed to evaluate positional accuracy, velocity constancy and accuracy for dynamic couch motion under a realistic weight load. A test evaluating the geometric accuracy of the system in delivering treatments over complex dynamic trajectories was also devised. Custom XML scripts that control the Varian TrueBeam™ STx (Serial #3) axes in Developer Mode were written to implement the delivery sequences for the tests. Delivered dose patterns were captured with radiographic film or the electronic portal imaging device. The couch translational accuracy in dynamic treatment mode was 0.01 cm. Rotational accuracy was within 0.3°, with 0.04 cm displacement of the rotational axis. Dose intensity profiles capturing the velocity constancy and accuracy for translations and rotation exhibited standard deviation and maximum deviations below 3%. For complex delivery involving MLC and couch motions, the overall translational accuracy for reproducing programmed patterns was within 0.06 cm. The authors conclude that in Developer Mode, TrueBeam™ is capable of delivering dynamic treatment delivery techniques involving couch motion with good geometric and dosimetric fidelity.

  1. Investigation of Skin Tribology and Its Effects on Coefficient of Friction and Other Tactile Attributes Involving Polymer Applications 

    E-Print Network [OSTI]

    Darden, Matthew Aguirre

    2012-02-14

    OF SKIN TRIBOLOGY AND ITS EFFECTS ON COEFFICIENT OF FRICTION AND OTHER TACTILE ATTRIBUTES INVOLVING POLYMER APPLICATIONS A Thesis by MATTHEW AGUIRRE DARDEN Submitted to the Office of Graduate Studies of Texas A&M University in partial... Tactile Attributes Involving Polymer Applications Copyright 2010 Matthew Aguirre Darden INVESTIGATION OF SKIN TRIBOLOGY AND ITS EFFECTS ON COEFFICIENT OF FRICTION AND OTHER TACTILE ATTRIBUTES INVOLVING POLYMER APPLICATIONS A Thesis...

  2. THE RELATIONSHIP BETWEEN HIGH INVOLVEMENT WORK SYSTEMS, SUPERVISORY SUPPORT, AND ORGANIZATIONAL EFFECTIVENESS: THE ROLE OF EMPLOYEE EXPERIENCES AT WORK

    E-Print Network [OSTI]

    Wadhwa, Preeti

    2012-08-31

    This study adopts a multilevel, multiple stakeholder perspective to examine the impact of high involvement work systems (HIWS) and supervisory support on organizational effectiveness. Organizational effectiveness is measured ...

  3. Involvement of purinergic system in inflammation and toxicity induced by copper in zebrafish larvae

    SciTech Connect (OSTI)

    Leite, Carlos Eduardo, E-mail: carlos.leite@pucrs.br [Instituto de Toxicologia e Farmacologia, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, CEP 90619-900 (Brazil); Programa de Pós-Graduação em Medicina: Ciências Médicas, Universidade Federal do Rio Grande do Sul, Porto Alegre, CEP 90035-003 (Brazil); Maboni, Lucas de Oliveira [Instituto de Toxicologia e Farmacologia, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, CEP 90619-900 (Brazil); Faculdade de Biociências, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, CEP 90619-900 (Brazil); Cruz, Fernanda Fernandes [Instituto de Toxicologia e Farmacologia, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, CEP 90619-900 (Brazil); Faculdade de Farmácia, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, CEP 90619-900 (Brazil); Rosemberg, Denis Broock [Programa de Pós-graduação em Ciências Ambientais, Universidade Comunitária da Região de Chapecó, Chapecó, CEP 89809-000 (Brazil); and others

    2013-11-01

    The use of zebrafish (Danio rerio) is increasing as an intermediate preclinical model, to prioritize drug candidates for mammalian testing. As the immune system of the zebrafish is quite similar to that of mammals, models of inflammation are being developed for the screening of new drugs. The characterization of these models is crucial for studies that seek for mechanisms of action and specific pharmacological targets. It is well known that copper is a metal that induces damage and cell migration to hair cells of lateral line of zebrafish. Extracellular nucleotides/nucleosides, as ATP and adenosine (ADO), act as endogenous signaling molecules during tissue damage by exerting effects on inflammatory and immune responses. The present study aimed to characterize the inflammatory status, and to investigate the involvement of the purinergic system in copper-induced inflammation in zebrafish larvae. Fishes of 7 days post-fertilization were exposed to 10 ?M of copper for a period of 24 h. The grade of oxidative stress, inflammatory status, copper uptake, the activity and the gene expression of the enzymes responsible for controlling the levels of nucleotides and adenosine were evaluated. Due to the copper accumulation in zebrafish larvae tissues, the damage and oxidative stress were exacerbated over time, resulting in an inflammatory process involving IL-1?, TNF-?, COX-2 and PGE{sub 2}. Within the purinergic system, the mechanisms that control the ADO levels were the most involved, mainly the reactions performed by the isoenzyme ADA 2. In conclusion, our data shed new lights on the mechanisms related to copper-induced inflammation in zebrafish larvae. - Graphical abstract: This scheme provides a chronological proposition for the biochemical events induced by copper in zebrafish larvae. The dashed line shows the absorption of copper over the exposure time. After 1 h of exposure to copper, the release of PGE{sub 2} occurs, followed by an increase of MPO (as a consequence of neutrophil migration), increased expression of genes involved in inflammatory events (IL-1? and TNF-?) and, reduction of the anti-inflammatory cytokine IL-10 at 4 h. At 24 h, the copper concentration is found highly increased, what is coincident with oxidative stress. Regarding the purinergic system, it is possible to observe an inhibition of ecto-5?-NT and ADA, with the consequent increase of AMP and ADA, respectively, at 24 h. The expression of enzyme-related genes shows a decrease in the expression of ecto-5?-NT and variable expressions of ADA subfamily enzymes. - Highlights: • Copper led to increased oxidative stress, and decreased the antioxidants' defenses. • Copper induced time-related changes of IL-1?, TNF-?, IL-10 and PGE{sub 2} levels. • ADA activity controls the levels of adenosine in copper-induced inflammation. • ADA 2 is the main ADA subfamily involved. • The purinergic system seems to be involved in the resolution of inflammation.

  4. Identification and Characterization of Soluble Factors Involved in Delayed Effects of Low Dose Radiation. Final report

    SciTech Connect (OSTI)

    Baulch, Janet

    2013-09-11

    This is a 'glue grant' that was part of a DOE Low Dose project entitled 'Identification and Characterization of Soluble Factors Involved in Delayed Effects of Low Dose Radiation'. This collaborative program has involved Drs. David L. Springer from Pacific Northwest National Laboratory (PNNL), John H. Miller from Washington State University, Tri-cities (WSU) and William F. Morgan then from the University of Maryland, Baltimore (UMB). In July 2008, Dr. Morgan moved to PNNL and Dr. Janet E. Baulch became PI for this project at University of Maryland. In November of 2008, a one year extension with no new funds was requested to complete the proteomic analyses. The project stemmed from studies in the Morgan laboratory demonstrating that genomically unstable cells secret a soluble factor or factors into the culture medium, that cause cytogenetic aberrations and apoptosis in normal parental GM10115 cells. The purpose of this project was to identify the death inducing effect (DIE) factor or factors, estimate their relative abundance, identify the cell signaling pathways involved and finally recapitulate DIE in normal cells by exogenous manipulation of putative DIE factors in culture medium. As reported in detail in the previous progress report, analysis of culture medium from the parental cell line, and stable and unstable clones demonstrated inconsistent proteomic profiles as relate to candidate DIE factors. While the proposed proteomic analyses did not provide information that would allow DIE factors to be identified, the analyses provided another important set of observations. Proteomic analysis suggested that proteins associated with the cellular response to oxidative stress and mitochondrial function were elevated in the medium from unstable clones in a manner consistent with mitochondrial dysfunction. These findings correlate with previous studies of these clones that demonstrated functional differences between the mitochondria of stable and unstable clones. These mitochondrial abnormalities in the unstable clones contributes to oxidative stress.

  5. LOFAR-UK White Paper: A Science case for UK involvement in LOFAR

    E-Print Network [OSTI]

    P. N. Best; the LOFAR-UK Consortium

    2008-02-08

    LOFAR, the Low-Frequency Array, is a next-generation software-driven radio telescope operating between 30 and 240MHz, currently under construction by ASTRON in the Netherlands. This low frequency radio band is one of the few largely unexplored regions of the electromagnetic spectrum. The sensitivity and angular resolution offered by LOFAR will be two to three orders of magnitude better than existing telescopes, and as such it will open up this new window on the Universe. LOFAR will impact on a broad range of astrophysics, from cosmology to solar system studies. There is growing European involvement in LOFAR, driven by the need to add stations far from the main core in order to improve angular resolution. LOFAR-UK is a project aimed at cementing UK participation in LOFAR via the operation of four stations within the UK. LOFAR-UK ground stations will allow LOFAR observations to reach sub-arcsecond scales at the highest frequencies, and as a result will also improve the (confusion-limited) sensitivity limit of the telescope for deep surveys. LOFAR-UK will achieve involvement for UK astronomers in a world-leading science facility operating in the immediate future. It will allow the UK to build up important scientific and technical expertise in `next generation' radio astronomy in preparation for the Square Kilometre Array (SKA), and will play an important role in broadening the UK community that has an interest in radio astronomy. This White Paper outlines the strategic importance to the UK astronomy community of gaining involvement in the LOFAR project, the scientific interests of UK researchers in using the telescope, and the technical challenges that will need to be overcome [abridged].

  6. Fatal accidents involving roof falls in coal mining, 1996--1998

    SciTech Connect (OSTI)

    Not Available

    1999-01-01

    This publication presents information on fatalities involving roof and rib falls that occurred in coal mining operations from January 1996 through December 1998. It includes statistics for the fatalities, as well as abstracts, best practices and illustrations. Conclusion statements have been substituted for best practices where no Title 30 Code of Regulations violations were cited during the accident investigation. From January 1996 through December 1998, 36 miners died at coal operations from accidents classified as roof falls. The information in the report is based on statistics taken from the 1996 through 1998 MSHA Fatal Illustration Programs: Roof Fall Fatalities by District.

  7. Fatal accidents involving roof falls in coal mining, 1996--1998

    SciTech Connect (OSTI)

    NONE

    1999-11-01

    This publication presents information on fatalities involving roof and rib falls that occurred in coal mining operations from January 1996 through December 1998. It includes statistics for the fatalities, as well as abstracts, best practices and illustrations. Conclusion statements have been substituted for best practices where no Title 30 Code of Regulations violations were cited during the accident investigation. From January 1996 through December 1998, 36 miners died at coal operations from accidents classified as roof falls. The information in the report is based on statistics taken from the 1996 through 1998 MSHA Fatal Illustration Programs: Roof Fall Fatalities by District.

  8. Use of Science in Gulf of Mexico Decision Making Involving Climate Change 

    E-Print Network [OSTI]

    Vedlitz, Arnold; Alston, Letitia T.; Laska, Shirley B.; Gramling, Robert B.; Harwell, Mark A.; Worthen, Helen D.

    2007-01-01

    Decision Making Involving Climate Change EPA COOPERATIVE AGREEMENT: R?83023601?0 September 2002 ? December 2007 Dr. ArnolD VeDlitz, Director & BoB Bullock chAir in GoVernment AnD PuBlic Policy institute for science, technoloGy AnD PuBlic Policy... Policy ? The Bush School ? Texas A&M University i Acknowledgements Research Support This material is based upon research supported by the U.S. Environmental Protection Agency's National Center for Environmental Assessment/Global Change Research...

  9. Involvement of ERK in NMDA receptor-independent cortical neurotoxicity of hydrogen sulfide

    SciTech Connect (OSTI)

    Kurokawa, Yuko; Sekiguchi, Fumiko; Kubo, Satoko; Yamasaki, Yoshiko; Matsuda, Sachi; Okamoto, Yukari; Sekimoto, Teruki; Fukatsu, Anna; Nishikawa, Hiroyuki [Division of Pharmacology and Pathophysiology, Kinki University School of Pharmacy, 3-4-1 Kowakae, Higashi-Osaka 577-8502 (Japan)] [Division of Pharmacology and Pathophysiology, Kinki University School of Pharmacy, 3-4-1 Kowakae, Higashi-Osaka 577-8502 (Japan); Kume, Toshiaki [Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-shimoadachi-cho, Sakyo-ku, Kyoto 606-8501 (Japan)] [Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-shimoadachi-cho, Sakyo-ku, Kyoto 606-8501 (Japan); Fukushima, Nobuyuki [Division of Molecular Neurobiology, Department of Life Sciences, Kinki University School of Science and Engineering, 3-4-1 Kowakae, Higashi-Osaka 577-8502 (Japan)] [Division of Molecular Neurobiology, Department of Life Sciences, Kinki University School of Science and Engineering, 3-4-1 Kowakae, Higashi-Osaka 577-8502 (Japan); Akaike, Akinori [Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-shimoadachi-cho, Sakyo-ku, Kyoto 606-8501 (Japan)] [Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-shimoadachi-cho, Sakyo-ku, Kyoto 606-8501 (Japan); Kawabata, Atsufumi, E-mail: kawabata@phar.kindai.ac.jp [Division of Pharmacology and Pathophysiology, Kinki University School of Pharmacy, 3-4-1 Kowakae, Higashi-Osaka 577-8502 (Japan)] [Division of Pharmacology and Pathophysiology, Kinki University School of Pharmacy, 3-4-1 Kowakae, Higashi-Osaka 577-8502 (Japan)

    2011-11-04

    Highlights: Black-Right-Pointing-Pointer Hydrogen sulfide causes NMDA receptor-independent neurotoxicity in mouse fetal cortical neurons. Black-Right-Pointing-Pointer Activation of ERK mediates the toxicity of hydrogen sulfide. Black-Right-Pointing-Pointer Apoptotic mechanisms are involved in the hydrogen-induced cell death. -- Abstract: Hydrogen sulfide (H{sub 2}S), a gasotransmitter, exerts both neurotoxicity and neuroprotection, and targets multiple molecules including NMDA receptors, T-type calcium channels and NO synthase (NOS) that might affect neuronal viability. Here, we determined and characterized effects of NaHS, an H{sub 2}S donor, on cell viability in the primary cultures of mouse fetal cortical neurons. NaHS caused neuronal death, as assessed by LDH release and trypan blue staining, but did not significantly reduce the glutamate toxicity. The neurotoxicity of NaHS was resistant to inhibitors of NMDA receptors, T-type calcium channels and NOS, and was blocked by inhibitors of MEK, but not JNK, p38 MAP kinase, PKC and Src. NaHS caused prompt phosphorylation of ERK and upregulation of Bad, followed by translocation of Bax to mitochondria and release of mitochondrial cytochrome c, leading to the nuclear condensation/fragmentation. These effects of NaHS were suppressed by the MEK inhibitor. Our data suggest that the NMDA receptor-independent neurotoxicity of H{sub 2}S involves activation of the MEK/ERK pathway and some apoptotic mechanisms.

  10. Polo-like Kinase I is involved in Invasion through Extracellular Matrix

    SciTech Connect (OSTI)

    Bissell, Mina J; Rizki, Aylin; Mott, Joni D.; Bissell, Mina J

    2008-04-02

    Polo-like kinase 1, PLK1, has important functions in maintaining genome stability and is involved in regulation of mitosis. PLK1 is up regulated in many invasive carcinomas. We asked whether it may also play a role in acquisition of invasiveness, a crucial step in transition to malignancy. In a model of metaplastic basal-like breast carcinoma progression, we found that PLK1 expression is necessary but not sufficient to induce invasiveness through laminin-rich extracellular matrix. PLK1 mediates invasion via Vimentin and {beta}1 integrin, both of which are necessary. We observed that PLK1 phosphorylates Vimentin on serine 82, which in turn regulates cell surface levels of {beta}1 integrin. We found PLK1 to be also highly expressed in pre-invasive in situ carcinomas of the breast. These results support a role for the involvement of PLK1 in the invasion process and point to this pathway as a potential therapeutic target for pre-invasive and invasive breast carcinoma treatment.

  11. Finding candidate genes under positive selection in Non-model species: examples of genes involved in host

    E-Print Network [OSTI]

    of positive selection were putatively involved in nutrient uptake from the host, secondary metabolite, UMR 7205, CNRS-MNHN, Origine, Structure et Evolution de la Biodiversite´, De´partement Syste and to develop vaccines or drugs. To elucidate the functions involved in host specialization, here we aimed

  12. Hydrogen Bonds Involved in Binding the Qi-site Semiquinone in the bc1 Complex, Identified through Deuterium Exchange

    E-Print Network [OSTI]

    Crofts, Antony R.

    Hydrogen Bonds Involved in Binding the Qi-site Semiquinone in the bc1 Complex, Identified through them. The strength of interactions indicates that the protons are involved in hydrogen bonds with SQ. The hyperfine cou- plings differ from values typical for in-plane hydrogen bonds previously observed in model

  13. To examine how the dynamics of recall processes are affected by the control processes involved with search termination, to study

    E-Print Network [OSTI]

    Dougherty, Michael

    involved with search termination, to study the implications of these control processes for the development at understanding the metacognitive control processes involved with the decision to terminate memory search. Specifically, research examines the impact of search termination decisions on the natural retrieval dynamics

  14. Examining the consistency relations describing the three-point functions involving tensors

    SciTech Connect (OSTI)

    Sreenath, V.; Sriramkumar, L., E-mail: sreenath@physics.iitm.ac.in, E-mail: sriram@physics.iitm.ac.in [Department of Physics, Indian Institute of Technology Madras, Chennai 600036 (India)

    2014-10-01

    It is well known that the non-Gaussianity parameter f{sub NL} characterizing the scalar bi-spectrum can be expressed in terms of the scalar spectral index in the squeezed limit, a property that is referred to as the consistency relation. In contrast to the scalar bi-spectrum, the three-point cross-correlations involving scalars and tensors and the tensor bi-spectrum have not received adequate attention, which can be largely attributed to the fact that the tensors had remained undetected at the level of the power spectrum until very recently. The detection of the imprints of the primordial tensor perturbations by BICEP2 and its indication of a rather high tensor-to-scalar ratio, if confirmed, can open up a new window for understanding the tensor perturbations, not only at the level of the power spectrum, but also in the realm of non-Gaussianities. In this work, we consider the consistency relations associated with the three-point cross-correlations involving scalars and tensors as well as the tensor bi-spectrum in inflationary models driven by a single, canonical, scalar field. Characterizing the cross-correlations in terms of the dimensionless non-Gaussianity parameters C{sub NL}{sup R} and C{sub NL}{sup ?} that we had introduced earlier, we express the consistency relations governing the cross-correlations as relations between these non-Gaussianity parameters and the scalar or tensor spectral indices, in a fashion similar to that of the purely scalar case. We also discuss the corresponding relation for the non-Gaussianity parameter h{sub NL} used to describe the tensor bi-spectrum. We analytically establish these consistency relations explicitly in the following two situations: a simple example involving a specific case of power law inflation and a non-trivial scenario in the so-called Starobinsky model that is governed by a linear potential with a sharp change in its slope. We also numerically verify the consistency relations in three types of inflationary models that permit deviations from slow roll and lead to scalar power spectra with features which typically result in an improved fit to the data than the more conventional, nearly scale invariant, spectra. We close with a summary of the results we have obtained.

  15. NRF2 activation is involved in ozonated human serum upregulation of HO-1 in endothelial cells

    SciTech Connect (OSTI)

    Pecorelli, Alessandra [Department of Molecular and Developmental Medicine, University of Siena (Italy); Child Neuropsychiatry Unit, University Hospital, AOUS, Siena (Italy); Bocci, Velio [Department of Physiology, University of Siena (Italy); Acquaviva, Alessandra [Department of Molecular and Developmental Medicine, University of Siena (Italy); Belmonte, Giuseppe [Department of Biomedical Sciences, University of Siena (Italy); Gardi, Concetta [Department of Molecular and Developmental Medicine, University of Siena (Italy); Virgili, Fabio [INRAN, Rome (Italy); Ciccoli, Lucia [Department of Molecular and Developmental Medicine, University of Siena (Italy); Valacchi, Giuseppe, E-mail: giuseppe.valacchi@unife.it [Department of Life Sciences and Biotechnology, University of Ferrara (Italy); Department of Food and Nutrition, Kyung Hee University, Seoul (Korea, Republic of)

    2013-02-15

    During the last decade, it has been shown that the activation of NRF2 and the binding to electrophile-responsive element (EpREs), stimulates the expression of a great number of genes responsible for the synthesis of phase I and phase II proteins, including antioxidants enzymes and heme oxygenase-1 (HO-1). This critical cell response occurs in cardiovascular, degenerative and chronic infective diseases aggravated by a chronic oxidative stress. In our previous reports we have shown that ozonated plasma is able to up-regulate HO-1 expression in endothelial cells. In the present work we investigated a candidate mechanism involved in this process. After treatment with increasing doses of ozonated serum (20, 40 and 80 ?g/mL O{sub 3} per mL of serum), a clear dose dependent activation of NRF2 and the subsequent induction of HO-1 and NAD(P)H quinone oxidoreductase 1(NQO1) was observed. This effect was also present when cells were treated with serum and hydrogen peroxide (H{sub 2}O{sub 2}) or serum and 4-hydroxynonenal (4HNE). Moreover, the treatment with ozonated serum was associated with a dose-dependent activation of extracellular-signal-regulated kinases (ERK1/2) and p38 MAP kinases (p38), not directly involved in NRF2 activation. These data, provide a new insight on the mechanism responsible for the induction of HO-1 expression by ozonated serum in the endothelium, and have a practical importance as an expedient approach to the treatment of patients with both effective orthodox drugs and ozonated autohemotherapy, targeted to the restoration of redox homeostasis. - Highlights: ? Endothelial HO1 is upregulated by ozonated plasma ? This activation is induced by NRF2 and it is ERK independent. ? 4HNE and H{sub 2}O{sub 2} are the main molecules involved in this process. ? Ozonated plasma induced a hormetic effect ? Combination of orthodox medicine and ozonated plasma can be a useful treatment.

  16. Pore scale modeling of reactive transport involved in geologic CO2 sequestration

    SciTech Connect (OSTI)

    Kang, Qinjin [Los Alamos National Laboratory; Lichtner, Peter C [Los Alamos National Laboratory; Viswanathan, Hari S [Los Alamos National Laboratory; Abdel-fattah, Amr I [Los Alamos National Laboratory

    2009-01-01

    We apply a multi-component reactive transport lattice Boltzmann model developed in previolls studies to modeling the injection of a C02 saturated brine into various porous media structures at temperature T=25 and 80 C. The porous media are originally consisted of calcite. A chemical system consisting of Na+, Ca2+, Mg2+, H+, CO2(aq), and CI-is considered. The fluid flow, advection and diHusion of aqueous species, homogeneous reactions occurring in the bulk fluid, as weB as the dissolution of calcite and precipitation of dolomite are simulated at the pore scale. The effects of porous media structure on reactive transport are investigated. The results are compared with continuum scale modeling and the agreement and discrepancy are discussed. This work may shed some light on the fundamental physics occurring at the pore scale for reactive transport involved in geologic C02 sequestration.

  17. Astrophysical S-factors for fusion reactions involving C, O, Ne and Mg isotopes

    E-Print Network [OSTI]

    M. Beard; A. V. Afanasjev; L. C. Chamon; L. R. Gasques; M. Wiescher; D. G. Yakovlev

    2010-02-03

    Using the Sao Paulo potential and the barrier penetration formalism we have calculated the astrophysical factor S(E) for 946 fusion reactions involving stable and neutron-rich isotopes of C, O, Ne, and Mg for center-of-mass energies E varying from 2 MeV to 18-30 MeV (covering the range below and above the Coulomb barrier). We have parameterized the energy dependence S(E) by an accurate universal 9-parameter analytic expression and present tables of fit parameters for all the reactions. We also discuss the reduced 3-parameter version of our fit which is highly accurate at energies below the Coulomb barrier, and outline the procedure for calculating the reaction rates. The results can be easily converted to thermonuclear or pycnonuclear reaction rates to simulate various nuclear burning phenomena, in particular, stellar burning at high temperatures and nucleosynthesis in high density environments.

  18. The Orosomucoid 1 protein is involved in the vitamin D – mediated macrophage de-activation process

    SciTech Connect (OSTI)

    Gemelli, Claudia, E-mail: claudia.gemelli@unimore.it [Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 287, 41125 Modena (Italy); Center for Regenerative Medicine, University of Modena and Reggio Emilia, Via Gottardi 100, 41125 Modena (Italy); Martello, Andrea; Montanari, Monica; Zanocco Marani, Tommaso; Salsi, Valentina; Zappavigna, Vincenzo; Parenti, Sandra; Vignudelli, Tatiana; Selmi, Tommaso; Ferrari, Sergio; Grande, Alexis [Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 287, 41125 Modena (Italy)

    2013-12-10

    Orosomucoid 1 (ORM1), also named Alpha 1 acid glycoprotein A (AGP-A), is an abundant plasma protein characterized by anti-inflammatory and immune-modulating properties. The present study was designed to identify a possible correlation between ORM1 and Vitamin D3 (1,25(OH)2D3), a hormone exerting a widespread effect on cell proliferation, differentiation and regulation of the immune system. In particular, the data described here indicated that ORM1 is a 1,25(OH)2D3 primary response gene, characterized by the presence of a VDRE element inside the 1 kb sequence of its proximal promoter region. This finding was demonstrated with gene expression studies, Chromatin Immunoprecipitation and luciferase transactivation experiments and confirmed by VDR full length and dominant negative over-expression. In addition, several experiments carried out in human normal monocytes demonstrated that the 1,25(OH)2D3 – VDR – ORM1 pathway plays a functional role inside the macrophage de-activation process and that ORM1 may be considered as a signaling molecule involved in the maintenance of tissue homeostasis and remodeling. - Highlights: • ORM1 is a Vitamin D primary response gene. • VD and its receptor VDR are involved in the de-activation process mediated by human resident macrophages. • The signaling pathway VD-VDR-ORM1 plays an important role in the control of macrophage de-activation process. • ORM1 may be defined as a signaling molecule implicated in the maintenance of tissue homeostasis and remodeling.

  19. Musashi2 modulates K562 leukemic cell proliferation and apoptosis involving the MAPK pathway

    SciTech Connect (OSTI)

    Zhang, Huijuan; Tan, Shi; Wang, Juan; Chen, Shana; Quan, Jing; Xian, Jingrong; Zhang, Shuai shuai; He, Jingang; Zhang, Ling, E-mail: lingzhang@cqmu.edu.cn

    2014-01-01

    The RNA-binding protein Musashi2 (Msi2) has been identified as a master regulator within a variety of stem cell populations via the regulation of translational gene expression. A recent study has suggested that Msi2 is strongly expressed in leukemic cells of acute myeloid leukemia patients, and elevated Msi2 is associated with poor prognosis. However, the potential role of Msi2 in leukemogenesis is still not well understood. Here, we investigated the effect of Msi2 knockdown on the biological properties of leukemic cells. High expression of Msi2 was found in K562 and KG-1a leukemic cell lines, and low expression was observed in the U937 cell line. We transduced K562 cells with two independent adenoviral shRNA vectors targeting Msi2 and confirmed knockdown of Msi2 at the mRNA and protein levels. Msi2 silencing inhibited cell growth and caused cell cycle arrest by increasing the expression of p21 and decreasing the expression of cyclin D1 and cdk2. In addition, knockdown of Msi2 promoted cellular apoptosis via the upregulation of Bax and downregulation of Bcl-2 expression. Furthermore, Msi2 knockdown resulted in the inactivation of the ERK/MAPK and p38/MAPK pathways, but no remarkable change in p-AKT was observed. These data provide evidence that Msi2 plays an important role in leukemogenesis involving the MAPK signaling pathway, which indicates that Msi2 may be a novel target for leukemia treatment. - Highlights: • Knockdown of Msi2 inhibited K562 cell growth and arrested cell cycle progression. • Knockdown of Msi2 induced K562 cell apoptosis via the regulation of Bax and Bcl-2. • The MAPK pathway was involved in the process of Msi2-mediated leukemogenesis. • Our data indicate that Msi2 is a potential new target for leukemia treatment.

  20. Exploring the Behavioral and Psychological Differences between Male and Female Youth with a History of Fire Involvement

    E-Print Network [OSTI]

    Morris, Ed M.

    2014-08-31

    Study objectives were to explore a sample of fire-involved youth by 1) describing their overall psychological characteristics, thoughts, and behaviors, 2) comparing the psychological characteristics, thoughts, and behaviors of their male and female...

  1. 6/6/2014 1 of 6 OHS 11-033 revision Animal Research Protocols Involving Hazardous Chemicals

    E-Print Network [OSTI]

    Kay, Mark A.

    OHS 11-033 revision Animal Research Protocols Involving Hazardous Chemicals I. OVERVIEW Hazardous Chemicals: Known or suspect carcinogens, reproductive toxins or other highly toxic substances (e. Reference the SU Chemical Hygiene Plan for hazardous chemical definitions. Potential Exposures: Research

  2. An Exploration of How Involvement in a Freshman Retention Program Relates to Intention to Complete an Undergraduate Degree

    E-Print Network [OSTI]

    Clounch, Teresa Lynn

    2010-07-15

    The study examined the relationship of the level and type of involvement of freshman students in the Hawk Link Retention Program, a first-year program at the University of Kansas, to intent to return and graduate. The study ...

  3. Finding Common Ground: Exploring the Experiences of Client Involvement in Medication Decisions Using a Shared Decision Making Model

    E-Print Network [OSTI]

    Goscha, Richard J.

    2009-12-01

    medications. Purposeful sampling, with an emphasis on achieving maximum variation, was used to better understand the interactive processes that contribute to as well as hinder client involvement in shared decision making. Multiple interviews with all...

  4. Vitellogenin Receptor and Neuropeptide Receptors Involved in Reproduction of the Red Imported Fire Ant (Solenopsis invicta Buren) 

    E-Print Network [OSTI]

    Lu, Hsiao Ling

    2012-02-14

    Social insects have complex forms of social organization. Molecular mechanisms involved in the regulation of their reproduction are not fully understood. This dissertation investigated the vitellogenin receptor (VgR), ...

  5. Community Involvement in the Preservation of World Heritage Sites: The Case of the Ukrainian Carpathian Wooden Churches 

    E-Print Network [OSTI]

    Schneider, Hans Rainer

    2013-05-30

    Encouraging the participation of the local population in the preservation of World Heritage Sites is one of the mission’s of UNESCO’s World Heritage Centre. Community involvement is also critical in the planning process. ...

  6. Involvement of voltage-sensitive calcium ion channels in release of luteinizing hormone-releasing hormone from the bovine infundibulum 

    E-Print Network [OSTI]

    Dippel, Wendy Wrae

    1993-01-01

    Bovine infundibular explants (INFE) were cultured to confirm calcium (Ca.) and voltage-sensitive calcium channel (VSCC) involvement in luteinizing hormone-releasing hormone (LHRH) release. Mid-sagitally sectioned INFE, randomly assigned to control...

  7. Endovascular Treatment of Infrarenal Abdominal Aortic Lesions With or Without Common Iliac Artery Involvement

    SciTech Connect (OSTI)

    Oender, Hakan; Oguzkurt, Levent; Guer, Serkan; Tekbas, Gueven; Guerel, Kamil; Coskun, Isa; Oezkan, Ugur

    2013-02-15

    To evaluate the results of stent placement for obstructive atherosclerotic aortic disease with or without involvement of the common iliac artery. Forty patients had self-expanding stents primarily or after balloon dilatation in the abdominal aorta between January 2005 and May 2011. All patients had trouble walking. Follow-up examinations were performed with clinical visits; these included color Doppler ultrasonography and computed tomographic angiography. Technical, clinical, and hemodynamic success was achieved in all patients. None of the patients underwent reintervention during the follow-up period, which ranged from 3 months to 6 years (median 24 months). Nine complications occurred in six patients. Of the nine complications, four were distal thromboembolisms, which were successfully treated with catheter-directed thrombolysis or anticoagulation therapy. Endovascular treatment of the obstructive aortic disease using self-expanding stents was safe and effective, with high technical success and long-term patency. Thromboembolic complications were high even though direct stenting was considered protective for thromboembolism formation. Particularly for infrarenal aortic stenosis, it can be recommended as the first-line treatment option for patients with obstructive atherosclerotic aortic disease.

  8. Risk of Developing Cardiovascular Disease After Involved Node Radiotherapy Versus Mantle Field for Hodgkin Lymphoma

    SciTech Connect (OSTI)

    Maraldo, Maja V., E-mail: dra.maraldo@gmail.com [Department of Radiation Oncology, Rigshospitalet, Copenhagen (Denmark); Brodin, Nils Patrik; Vogelius, Ivan R.; Aznar, Marianne C.; Munck af Rosenschoeld, Per; Petersen, Peter M. [Department of Radiation Oncology, Rigshospitalet, Copenhagen (Denmark); Specht, Lena [Department of Radiation Oncology, Rigshospitalet, Copenhagen (Denmark); Faculty of Health Sciences, University of Copenhagen, Copenhagen (Denmark)

    2012-07-15

    Purpose: Hodgkin lymphoma (HL) survivors are known to have increased cardiac mortality and morbidity. The risk of developing cardiovascular disease after involved node radiotherapy (INRT) is currently unresolved, inasmuch as present clinical data are derived from patients treated with the outdated mantle field (MF) technique. Methods and Materials: We included all adolescents and young adults with supradiaphragmatic, clinical Stage I-II HL treated at our institution from 2006 to 2010 (29 patients). All patients were treated with chemotherapy and INRT to 30 to 36 Gy. We then simulated a MF plan for each patient with a prescribed dose of 36 Gy. A logistic dose-response curve for the 25-year absolute excess risk of cardiovascular disease was derived and applied to each patient using the individual dose-volume histograms. Results: The mean doses to the heart, four heart valves, and coronary arteries were significantly lower for INRT than for MF treatment. However, the range in doses with INRT treatment was substantial, and for a subgroup of patients, with lymphoma below the fourth thoracic vertebrae, we estimated a 25-year absolute excess risk of any cardiac event of as much as 5.1%. Conclusions: Our study demonstrates a potential for individualizing treatment by selecting the patients for whom INRT provides sufficient cardiac protection for current technology; and a subgroup of patients, who still receive high cardiac doses, who would benefit from more advanced radiation technique.

  9. Identification of a Xylogalacturonan Xylosyltransferase Involved in Pectin Biosynthesis in Arabidopsis

    SciTech Connect (OSTI)

    Pauly, Markus; Sorensen, Susanne Oxenboll; Harholt, Jesper; Geshi, Naomi; Sakuragi, Yumiko; Moller, Isabel; Zandleven, Joris; Bernal, Adriana J.; Jensen, Niels Bjerg; Sorensen, Charlotte; Jensen, Jacob K.; Beldman, Gerrit; Willats, William G.T.; Scheller, Henrik

    2009-08-19

    Xylogalacturonan (XGA) is a class of pectic polysaccharide found in plant cell walls. The Arabidopsis thaliana locus At5g33290 encodes a predicted Type II membrane protein, and insertion mutants of the At5g33290 locus had decreased cell wall xylose. Immunological studies, enzymatic extraction of polysaccharides, monosaccharide linkage analysis, and oligosaccharide mass profiling were employed to identify the affected cell wall polymer. Pectic XGA was reduced to much lower levels in mutant than in wild-type leaves, indicating a role of At5g33290 in XGA biosynthesis. The mutated gene was designated xylogalacturonan deficient1 (xgd1). Transformation of the xgd1-1 mutant with the wild-type gene restored XGA to wild-type levels. XGD1 protein heterologously expressed in Nicotiana benthamiana catalyzed the transfer of xylose from UDP-xylose onto oligogalacturonides and endogenous acceptors. The products formed could be hydrolyzed with an XGA-specific hydrolase. These results confirm that the XGD1 protein is a XGA xylosyltransferase. The protein was shown by expression of a fluorescent fusion protein in N. benthamiana to be localized in the Golgi vesicles as expected for a glycosyltransferase involved in pectin biosynthesis.

  10. Spred2 is involved in imatinib-induced cytotoxicity in chronic myeloid leukemia cells

    SciTech Connect (OSTI)

    Liu, Xiao-Yun; Yang, Yue-Feng; Wu, Chu-Tse; Xiao, Feng-Jun; Zhang, Qun-Wei [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850 (China)] [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850 (China); Ma, Xiao-Ni [Lanzhou University of Technology, Lanzhou 730050 (China)] [Lanzhou University of Technology, Lanzhou 730050 (China); Li, Qing-Fang; Yan, Jun [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850 (China)] [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850 (China); Wang, Hua, E-mail: wanghualjh@gmail.com [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850 (China)] [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850 (China); Wang, Li-Sheng, E-mail: wangls@nic.bmi.ac.cn [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850 (China)] [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850 (China)

    2010-03-19

    Spreds, a recently established class of negative regulators of the Ras-ERK (extracellular signal-regulated kinase) pathway, are involved in hematogenesises, allergic disorders and tumourigenesis. However, their role in hematologic neoplasms is largely unknown. Possible effects of Spreds on other signal pathways closely related to Ras-ERK have been poorly investigated. In this study, we investigated the in vitro effects of Spred2 on chronic myeloid leukemia (CML) cells. In addition to inhibiting the well-established Ras-ERK cascade, adenovirus-mediated Spred2 over-expression inhibits constitutive and stem cell factor (SCF)-stimulated sphingosine kinase-1 (SPHK1) and Mcl-1 expression, as well as inhibiting proliferation and inducing apoptosis in CML cells. In K562 cells and primary CML cells, imatinib induces endogenous Spred2 expression. Spred2 silencing by stable RNA interference partly protects K562 cells against imatinib-induced apoptosis. Together, these data implicate Spred2 in imatinib-induced cytotoxicity in CML cells, possibly by inhibiting the Ras-ERK cascade and the pro-survival signaling molecules SPHK1 and Mcl-1. These findings reveal potential targets for selective therapy of CML.

  11. Fracture Mechanics implications for apparent static friction coefficient in contact problems involving slip-weakening laws

    E-Print Network [OSTI]

    A. Papangelo; M. Ciavarella; J. R. Barber

    2015-06-19

    We consider the effect of differing coefficients of static and dynamic friction coefficients on the behaviour of contacts involving microslip. The classic solutions of Cattaneo and Mindlin are unchanged if the transition in coefficients is abrupt, but if it occurs over some small slip distance, the solution has some mathematical similarities with those governing the normal tractions in adhesive contact problems. In particular, if the transition to dynamic slip occurs over a sufficiently small area, we can identify a `JKR' approximation, where the transition region is condensed to a line. A local singularity in shear traction is then predicted, with a stress-intensity factor that is proportional to the the square root of the local contact pressure and to a certain integral of the friction coefficient-slip distance relation. We can also define an equivalent of the `small-scale yielding' criterion, which enables us to assess when the singular solution provides a good approximation. One consequence of the results is that the static coefficient of friction determined from force measurements in experiments is significantly smaller than the value that holds at the microscale.

  12. Involvement of growth factors and their receptors in radon-induced rat lung tumors

    SciTech Connect (OSTI)

    Leung, F.C.; Dagle, G.E.; Cross, F.T. [Pacific Northwest Lab., Richland, WA (United States)

    1992-12-31

    In this paper we examine the role of growth factors (GF) and their receptors (GFR) in radon-induced rat lung tumors. Inhalation exposure of radon and its daughters induced lung tumors in rats, but the molecule/cellular mechanisms are not known. Recent evidence suggests that GF/GFR play a critical role in the growth and development of lung cancer in humans and animals. We have developed immunocytochemical methods for identifying sites of production and action of GF/GFR at the cellular level; for example, the avidin-biotin horseradish peroxidase technique. In radon-induced rat epidermoid carcinomas, epidermal growth factor (EGF), EGF-receptors (EGF-R), transforming growth factor alpha (TGF-{alpha}), and bombesin were found to be abnormally expressed. These abnormal expressions, mainly associated with epidermoid carcinomas of the lung, were not found in any other lung tumor types. Our data suggest that EGF, EGF-R, TGF-{alpha}, and bombesin are involved in radon oncogenesis in rat lungs, especially in epidermoid carcinomas, possibly through the autocrine/paracrine pathway.

  13. Involvement of Arabidopsis RACK1 in Protein Translation and Its Regulation by Abscisic Acid

    SciTech Connect (OSTI)

    Guo, Jianjun [University of British Columbia, Vancouver; Wang, Shucai [University of British Columbia, Vancouver; Valerius, Oliver [Universitaet Goettingen, Goettingen, Germany; Hall, Hardy [University of British Columbia, Vancouver; Zeng, Qingning [University of British Columbia, Vancouver; Li, Jian-Feng [Harvard University; Weston, David [ORNL; Ellis, Brian [University of British Columbia, Vancouver; Chen, Jay [ORNL

    2011-01-01

    Earlier studies have shown that RACK1 functions as a negative regulator of ABA responses in Arabidopsis, but the molecular mechanism of the action of RACK1 in these processes remains elusive. Global gene expression profiling revealed that approximately 40% of the genes affected by ABA treatment were affected in a similar manner by the rack1 mutation, supporting the view that RACK1 is an important regulator of ABA responses. On the other hand, co-expression analysis revealed that >80% of the genes co-expressed with RACK1 encode ribosome proteins, implying a close relationship between RACK1 s function and the ribosome complex. These results implied that the regulatory role for RACK1 in ABA responses may be partially due to its putative function in protein translation, which is one of the major cellular processes that mammalian and yeast RACK1 is involved in. Consistently, all three Arabidopsis RACK1 homologous genes, namely RACK1A, RACK1B and RACK1C, complemented the growth defects of the S. cerevisiae cpc2/rack1 mutant. In addition, RACK1 physically interacts with Arabidopsis Eukaryotic Initiation Factor 6 (eIF6), whose mammalian homologue is a key regulator of 80S ribosome assembly. Moreover, rack1 mutants displayed hypersensitivity to anisomycin, an inhibitor of protein translation, and displayed characteristics of impaired 80S functional ribosome assembly and 60S ribosomal subunit biogenesis in a ribosome profiling assay. Gene expression analysis revealed that ABA inhibits the expression of both RACK1 and eIF6. Taken together, these results suggest that RACK1 may be required for normal production of 60S and 80S ribosomes and that its action in these processes may be regulated by ABA.

  14. Consent Versus Consensus - Stakehold Involvement in the Identification of Necessary and Sufficient Transportation

    SciTech Connect (OSTI)

    Fawcett, Ricky Lee; Kramer, George Leroy Jr.

    2003-03-01

    Transportation (DOT) and the Nuclear Regulatory Commission (NRC) to provide for the protection of the public and the environment; historically these regulations have proven quite sufficient. Even so, when the Department of Energy (DOE) makes radioactive materials shipments, that are deemed to be a major federal activity, regulations under the National Environmental Policy Act require that public input on safety issues be sought. This requirement leads to interactions with State, Tribal and local stakeholders that often result in the imposition of extra-regulatory requirements – requirements beyond those prescribed by DOT and NRC regulations. Unfortunately, these additional requirements virtually always increase costs and delay schedules, and usually do so without significantly increasing, and possibly even decreasing overall transportation safety. We believe that this problem arises because of efforts to achieve stakeholder consensus rather than stakeholder consent, where “consensus” connotes universal agreement with all aspects of the program, while “consent”, as used here, is simple agreement with the overall course of action. Gaining consensus entails extensive negotiations because all aspects and requirements of the project must be agreed to by each stakeholder. Gaining consent, on the other hand, requires only that stakeholders be satisfied that the project, as planned, provides adequately for their safety needs. This article addresses the issue of consent versus consensus and proposes a systematic, decision science process for reaching consent. Key steps in this proposed process are early identification and involvement of stakeholders, compilation of their concerns, perceptions, needs, causes, and translation of that information into an appropriate set of “derived requirements.” These derived requirements, along with already-established DOT and NRC regulatory requirements, form the necessary and sufficient conditions for safe transportation and for obtaining stakeholder consent.

  15. Substrate binding by a bacterial ABC transporter involved in polysaccharide export

    SciTech Connect (OSTI)

    Cuthbertson, Leslie; Kimber, Matthew S.; Whitfield, Chris (Guelph)

    2008-04-02

    ATP-binding-cassette (ABC) transporters are responsible for the export of a wide variety of cell-surface glycoconjugates in both Gram-positive and Gram-negative bacteria. These include the O-antigenic polysaccharide (O-PS) portion of lipopolysaccharide, a crucial virulence determinant in Gram-negative pathogens. O-PSs are synthesized by one of two fundamentally different pathways. Escherichia coli O serotypes O8 and O9a provide the prototype systems for studying O-PS export via ABC transporters. The transporter is composed of the transmembrane component Wzm and the nucleotide-binding component Wzt. Although the N-terminal domain of Wzt is a conventional ABC protein, the C-terminal domain of Wzt (C-Wzt) is a unique structural element that determines the specificity of the transporter for either the O8 or O9a O-PS. We show here that the two domains of Wzt can function when expressed as separate polypeptides; both are essential for export. In vitro, C-Wzt binds its cognate O-PS by recognizing a residue located at the nonreducing end of the polymer. The crystal structure of C-WztO9a is reported here and reveals a {beta} sandwich with an immunoglobulin-like topology that contains the O-PS-binding pocket. Substrate interactions with nucleotide-binding domains have been demonstrated in an ABC exporter previously. However, to our knowledge substrate binding by a discrete, cytoplasmic accessory domain in an extended nucleotide-binding domain polypeptide has not previously been demonstrated. Elucidation of the substrate-recognition system involved in O-PS export provides insight into the mechanism that coordinates polymer biosynthesis, termination, and export.

  16. Involvement of the transcription factor FoxM1 in contact inhibition

    SciTech Connect (OSTI)

    Faust, Dagmar; Al-Butmeh, Firas; Linz, Berenike [Institute of Toxicology, Medical Center of the Johannes Gutenberg-University, Obere Zahlbacherstr. 67, 55131 Mainz (Germany)] [Institute of Toxicology, Medical Center of the Johannes Gutenberg-University, Obere Zahlbacherstr. 67, 55131 Mainz (Germany); Dietrich, Cornelia, E-mail: cdietric@uni-mainz.de [Institute of Toxicology, Medical Center of the Johannes Gutenberg-University, Obere Zahlbacherstr. 67, 55131 Mainz (Germany)] [Institute of Toxicology, Medical Center of the Johannes Gutenberg-University, Obere Zahlbacherstr. 67, 55131 Mainz (Germany)

    2012-10-05

    Highlights: Black-Right-Pointing-Pointer The transcription factor FoxM1 is downregulated upon contact inhibition. Black-Right-Pointing-Pointer The decrease in FoxM1 levels occurs very likely due to inhibition of ERK activity. Black-Right-Pointing-Pointer The decrease in FoxM1 is not sufficient, but required for contact inhibition. Black-Right-Pointing-Pointer We propose a new model of contact inhibition involving pRB/E2F and FoxM1. -- Abstract: Contact inhibition is a crucial mechanism regulating proliferation in vitro and in vivo. Although it is generally accepted that contact inhibition plays a pivotal role in maintaining tissue homeostasis, the molecular mechanisms of contact inhibition are still not fully understood. FoxM1 is known as a proliferation-associated transcription factor and is upregulated in many cancer types. Vice versa, anti-proliferative signals, such as TGF-{beta} and differentiation signals decrease FoxM1 expression. Here we investigated the role of FoxM1 in contact inhibition in fibroblasts. We show that protein expression of FoxM1 is severely and rapidly downregulated upon contact inhibition, probably by inhibition of ERK activity, which then leads to decreased expression of cyclin A and polo-like kinase 1. Vice versa, ectopic expression of FoxM1 prevents the decrease in cyclin A and polo-like kinase 1 and causes a two-fold increase in saturation density indicating loss of contact inhibition. Hence, we show that downregulation of FoxM1 is required for contact inhibition by regulating expression of cyclin A and polo-like kinase 1.

  17. Public Involvement Plan Public Involvement Plan

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious RankADVANCED MANUFACTURINGEnergy BillsNo. 195 - Oct. 7, 2011 | DepartmentFunds for2002 | DepartmentPublic

  18. GM Project G.6 1 -1 October 2000 1. INTRODUCTION

    E-Print Network [OSTI]

    behavior and patterns of the elderly, an investigation of the influence of various factors on older drivers, and · The total number of all occupant and non-occupant fatalities (all ages) resulting from crashes in which

  19. Report on International Collaboration Involving the FE Heater and HG-A Tests at Mont Terri

    SciTech Connect (OSTI)

    Houseworth, Jim; Rutqvist, Jonny; Asahina, Daisuke; Chen, Fei; Vilarrasa, Victor; Liu, Hui-Hai; Birkholzer, Jens

    2013-11-06

    Nuclear waste programs outside of the US have focused on different host rock types for geological disposal of high-level radioactive waste. Several countries, including France, Switzerland, Belgium, and Japan are exploring the possibility of waste disposal in shale and other clay-rich rock that fall within the general classification of argillaceous rock. This rock type is also of interest for the US program because the US has extensive sedimentary basins containing large deposits of argillaceous rock. LBNL, as part of the DOE-NE Used Fuel Disposition Campaign, is collaborating on some of the underground research laboratory (URL) activities at the Mont Terri URL near Saint-Ursanne, Switzerland. The Mont Terri project, which began in 1995, has developed a URL at a depth of about 300 m in a stiff clay formation called the Opalinus Clay. Our current collaboration efforts include two test modeling activities for the FE heater test and the HG-A leak-off test. This report documents results concerning our current modeling of these field tests. The overall objectives of these activities include an improved understanding of and advanced relevant modeling capabilities for EDZ evolution in clay repositories and the associated coupled processes, and to develop a technical basis for the maximum allowable temperature for a clay repository. The R&D activities documented in this report are part of the work package of natural system evaluation and tool development that directly supports the following Used Fuel Disposition Campaign (UFDC) objectives: ? Develop a fundamental understanding of disposal-system performance in a range of environments for potential wastes that could arise from future nuclear-fuel-cycle alternatives through theory, simulation, testing, and experimentation. ? Develop a computational modeling capability for the performance of storage and disposal options for a range of fuel-cycle alternatives, evolving from generic models to more robust models of performance assessment. For the purpose of validating modeling capabilities for thermal-hydro-mechanical (THM) processes, we developed a suite of simulation models for the planned full-scale FE Experiment to be conducted in the Mont Terri URL, including a full three-dimensional model that will be used for direct comparison to experimental data once available. We performed for the first time a THM analysis involving the Barcelona Basic Model (BBM) in a full three-dimensional field setting for modeling the geomechanical behavior of the buffer material and its interaction with the argillaceous host rock. We have simulated a well defined benchmark that will be used for codeto- code verification against modeling results from other international modeling teams. The analysis highlights the complex coupled geomechanical behavior in the buffer and its interaction with the surrounding rock and the importance of a well characterized buffer material in terms of THM properties. A new geomechanical fracture-damage model, TOUGH-RBSN, was applied to investigate damage behavior in the ongoing HG-A test at Mont Terri URL. Two model modifications have been implemented so that the Rigid-Body-Spring-Network (RBSN) model can be used for analysis of fracturing around the HG-A microtunnel. These modifications are (1) a methodology to compute fracture generation under compressive stress conditions and (2) a method to represent anisotropic elastic and strength properties. The method for computing fracture generation under compressive load produces results that roughly follow trends expected for homogeneous and layered systems. Anisotropic properties for the bulk rock were represented in the RBSN model using layered heterogeneity and gave bulk material responses in line with expectations. These model improvements were implemented for an initial model of fracture damage at the HG-A test. While the HG-A test model results show some similarities with the test observations, differences between the model results and observations remain.

  20. Early Brain Response to Low-Dose Radiation Exposure Involves Molecular Networks and Pathways Associated with Cognitive Functions, Advanced Aging and Alzheimer's Disease

    E-Print Network [OSTI]

    Lowe, Xiu R

    2009-01-01

    Early brain response to low-dose radiation exposure involvesRunning Title: Low dose radiation affects cognitive functionEarly brain response to low-dose radiation exposure involves

  1. Autism: Reduced Connectivity between Cortical Areas Involved in Face Expression, Theory of Mind, and the Sense of Self

    E-Print Network [OSTI]

    Feng, Jianfeng

    1 Autism: Reduced Connectivity between Cortical Areas Involved in Face Expression, Theory of Mind head: Functional connectivity in autism # These authors contributed equally to this work resting-state functional connectivity was analyzed in 523 people with autism and 452 typically developing

  2. Robotics Minor Robotics is a truly interdisciplinary minor, involving expertise in the fields of computer science, electrical

    E-Print Network [OSTI]

    Massachusetts at Lowell, University of

    Robotics Minor Robotics is a truly interdisciplinary minor, involving expertise in the fields-requisites to the minor courses: Calculus I, Calculus II, Physics I, and Physics II or electricity. Robotics Minor.265 Logic Design 16.317 Microprocessors Systems Design I 22.211 Statics 22.213 Dynamics 22.579 Robotics

  3. Holistic Therapy Holistic Massage: This hour long session involves a complete relaxation of the body while easing

    E-Print Network [OSTI]

    O'Mahony, Donal E.

    Elements Holistic Therapy Clinic Holistic Massage: This hour long session involves a complete. Leaving you re-vitalised, supple and ready for life. 1 ½ hours available. Back, Neck and Shoulders boost Massage: This half an hour session relieves the back of stress knots and stiffness built up within

  4. CER4 Encodes an Alcohol-Forming Fatty Acyl-Coenzyme A Reductase Involved in Cuticular Wax Production

    E-Print Network [OSTI]

    Kunst, Ljerka

    CER4 Encodes an Alcohol-Forming Fatty Acyl-Coenzyme A Reductase Involved in Cuticular Wax surfaces of land plants. It is composed of a cutin polymer matrix and waxes. Cuticular waxes are complex and characterization of CER4, a wax bio- synthetic gene from Arabidopsis (Arabidopsis thaliana). Arabidopsis cer4

  5. What is Your Environmental Wellness? The environmental dimension involves accepting the impact we have on our world and doing something

    E-Print Network [OSTI]

    What is Your Environmental Wellness? The environmental dimension involves accepting the impact we sprays. _____ 7. I do not litter. _____ 8. I volunteer my time for environmental conservation projects about doing my part to preserve the environment. _____ Total for Environmental Wellness SCORE MEANING 15

  6. Bottomonium spectroscopy and radiative transitions involving the ?[subscript bJ](1P,2P) states at BaBar

    E-Print Network [OSTI]

    Lees, J.?P.

    We use (121 ± 1) million ?(3S) and (98 ± 1) million ?(2S) mesons recorded by the BABAR detector at the PEP-II e[superscript +]e[superscript -] collider at SLAC to perform a study of radiative transitions involving the ...

  7. Identification and characterization of a pyridoxal reductase involved in the vitamin B6 salvage pathway in Arabidopsis

    E-Print Network [OSTI]

    Daub, Margaret

    Identification and characterization of a pyridoxal reductase involved in the vitamin B6 salvage Springer Science+Business Media B.V. 2011 Abstract Vitamin B6 (pyridoxal phosphate) is an essen- tial between the six vitamin B6 vitamers. A putative pyridoxal reductase (PLR1) was identified in Arabidopsis

  8. 162 Electrical and Computer Engineering 163 Courses and projects that actively involve them in their own education and

    E-Print Network [OSTI]

    Richards-Kortum, Rebecca

    · A broad education outside of engineering and science that emphasizes the role of electrical and computer162 Electrical and Computer Engineering 163 · Courses and projects that actively involve them in their own education and enhance their ability to formulate and solve real-world design and research problems

  9. Supply chain management (SCM) involves the management of materials and information across the entire supply chain. This includes raw material

    E-Print Network [OSTI]

    Calgary, University of

    the entire supply chain. This includes raw material suppliers, component producers, final assemblySupply chain management (SCM) involves the management of materials and information across this concentration will be required to take three core courses: Materials and Supply Chain Management, Transportation

  10. Benzodiazepine Withdrawal-Induced Glutamatergic Plasticity Involves Up-Regulation of GluR1-Containing -Amino-3-

    E-Print Network [OSTI]

    Abraham, Nader G.

    Benzodiazepine Withdrawal-Induced Glutamatergic Plasticity Involves Up-Regulation of GluR1 and addiction. Benzodiazepine withdrawal results in increased glutamatergic strength, but whether -amino-3 remodeled during benzodiazepine withdrawal is uncertain. Whole-cell recordings of rat hippocampal CA1

  11. In this effort, we describe a face database obtained by using an involved acquisition system for the collection of

    E-Print Network [OSTI]

    Abidi, Mongi A.

    relies heavily on illumination. Thermal IR imagery, being a representation of the radiated thermal energy when involving multi-band visible and thermal information. The database has applications/monochromatic image, one thermal image and the spectral distribution of the illumination of the scene. The complete

  12. Distinct osmo-sensing protein kinase pathways are involved in signalling moderate and severe hyper-osmotic

    E-Print Network [OSTI]

    Hirt, Heribert

    Distinct osmo-sensing protein kinase pathways are involved in signalling moderate and severe hyper-osmotic is severely affected by hyper-osmotic salt conditions. Although a number of salt-induced genes have been and extreme hyper-osmotic conditions. A 46 kDa protein kinase was found to be activated by elevated salt

  13. Transportation of Dangerous Goods Anyone involved with the Transportation of Dangerous Goods must be trained. This includes shipping

    E-Print Network [OSTI]

    TDG Transportation of Dangerous Goods Anyone involved with the Transportation of Dangerous Goods must be trained. This includes shipping and receiving. All receiving of Dangerous Goods for the Science in Departmental Offices or labs. How do you know if the package is a dangerous goods shipment? Parcels containing

  14. Whether it's designing rehabilitation strategies involving electricity to `retrain' damaged nerves, developing optical imaging systems to build

    E-Print Network [OSTI]

    Whether it's designing rehabilitation strategies involving electricity to `retrain' damaged nerves-ready rehabilitation products is only part of the equation. As part of her CARE (CREATE Academic Rehabilitation in the commercialization of two important rehabilitation products for the Staxi Corporation.Working out of the iDAPT `Home

  15. The Effects of an Intervention to Foster a Caring and Task-Involving Climate at a University Recreation Center

    E-Print Network [OSTI]

    Brown, Theresa Clare

    2011-04-21

    of the following: a) climate (e.g. perceptions of the caring, task-, and ego-involving climates), b) psychological needs (e.g. autonomy, competence, and relatedness), c) motivational responses (e.g. extrinsic and intrinsic motivation), d) commitment to exercise...

  16. Involvement of Extracellular Signal-Regulated Kinase (ERK) in Pardaxin-Induced Dopamine Release from PC12 Cells

    E-Print Network [OSTI]

    Linial, Michal

    Involvement of Extracellular Signal-Regulated Kinase (ERK) in Pardaxin-Induced Dopamine Release kinase (ERK)/mitogen-activated protein kinase (MAPK) in pardaxin-induced dopamine (DA) release DA release. Time course exper- iments indicated that PX, at nontoxic concentrations, stimu- lated ERK

  17. Planning for multiple mobile robots in dynamic environ-ments involves determining the optimal path each robot

    E-Print Network [OSTI]

    Stentz, Tony

    Abstract Planning for multiple mobile robots in dynamic environ- ments involves determining the optimal path each robot should follow to accomplish the goals of the mission, given the current knowledge reassign robots to goals in order to continually minimize the time to complete the mission. In this paper

  18. A Lipid-modified Phosphoinositide-specific Phospholipase C (TcPI-PLC) Is Involved in Differentiation of Trypomastigotes to

    E-Print Network [OSTI]

    Singer, Randall

    A Lipid-modified Phosphoinositide-specific Phospholipase C (TcPI-PLC) Is Involved C (PI- PLC) is an important component of the inositol phos- phate/diacylglycerol signaling pathway. A newly discov- ered Trypanosoma cruzi PI-PLC (TcPI-PLC) is lipid modified in its N terminus, targeted

  19. Human Fertilisation and Embryology Bill A briefing for MPs on the need for research involving human and human admixed embryos.

    E-Print Network [OSTI]

    Rambaut, Andrew

    cells for research. The Bill allows research, under license, on four types of HAEs, which contain bothHuman Fertilisation and Embryology Bill A briefing for MPs on the need for research involving human and human admixed embryos. Prepared by the Academy of Medical Sciences, the Medical Research Council

  20. Mass Spectroscopy of Chemical Reaction of 3d Metal Clusters Involved in Chemical Vapor Deposition Synthesis of Carbon Nanotubes

    E-Print Network [OSTI]

    Maruyama, Shigeo

    -labeled experiments. KEYWORDS: cluster, iron, cobalt, nickel, FT-ICR, single-walled carbon nanotubes *Present address Synthesis of Carbon Nanotubes Shuhei Inoue* and Shigeo Maruyama Department of Mechanical Engineering importance. For example, these reactions are involved in the synthesis of single-walled carbon nanotubes

  1. NPS Institutional Review Board (IRB) Interim Guidance on Human Subjects Research Involving Surveys, Questionnaires, Interviews, and Focus Groups

    E-Print Network [OSTI]

    NPS Institutional Review Board (IRB) Interim Guidance on Human Subjects Research Involving Surveys only those data collection activities related to human subjects research. To ensure NPS by the IRB must balance the needs, responsibilities, and risks related to the research subjects, the student

  2. Honours Programmes involving Physics and Astronomy, March 2015 Page 1 Entering SH within Physics and Astronomy and Joint Degrees -2015

    E-Print Network [OSTI]

    Greenaway, Alan

    Honours Programmes involving Physics and Astronomy, March 2015 Page 1 Entering SH within Physics subject to University approvals, we plan to offer BSc Mathematics and Physics students a choice of Maths or Physics project. Some details of the modules open to you are in the University's Course Catalogue

  3. GM Project G.6 October 20008 -1 8. FATAL CRASH RATES

    E-Print Network [OSTI]

    GM Project G.6 October 20008 - 1 8. FATAL CRASH RATES 8.1 MODELING FATALITY RATES FOR OLDER DRIVERS of the country. #12;GM Project G.6 October 20008 - 2 Figure 8.1. Historical Elderly Driver Fatality Rate By Age 100 million miles) #12;GM Project G.6 October 20008 - 3 The other fatality risk concept we project

  4. Involvement of a eukaryotic-like ubiquitin-related modifier in the proteasome pathway of the archaeon Sulfolobus acidocaldarius

    E-Print Network [OSTI]

    Anjum, Rana S.; Bray, Sian M.; Blackwood, John K.; Kilkenny, Mairi L.; Coelho, Matthew A.; Foster, Benjamin M.; Li, Shurong; Howard, Julie A.; Pellegrini, Luca; Albers, Sonja-Verena; Deery, Michael J.; Robinson, Nicholas P.

    2015-01-01

    1 Involvement of a eukaryotic-like ubiquitin-related modifier in the proteasome pathway of the archaeon Sulfolobus acidocaldarius. Rana S. Anjum 1*, Sian M. Bray 1*, John K. Blackwood 1, Mairi L. Kilkenny 1, Matthew A. Coelho... , UK. 2) Cambridge Centre for Proteomics, Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, UK. 3) Molecular Biology of Archaea, Max Planck Institute for Terrestrial Microbiology, 35043...

  5. Regulatory Drivers | netl.doe.gov

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    vehicles or motor vehicle engines "which in his judgment causes, or contributes to, air pollution which may reasonably be anticipated to endanger public health or welfare."7...

  6. DESCRIPTION OF ACCIDENT MSU DRIVERS SIGNATURE

    E-Print Network [OSTI]

    Dyer, Bill

    of Commercial Policy Number) Motor vehicles that are owned, rented, leased, or loaned to Montana State's Name: MSU VEHICLE (VEHICLE #1) Issued Citation: YES NO Explain: Department: Phone: 994 - Vehicle Owner: Use of Vehicle: Vehicle: Make Model Year VIN: Plate Number: State: Description of Damage: Safety

  7. Residential Prosumers: Drivers and Policy Options

    Office of Energy Efficiency and Renewable Energy (EERE)

    The rise of the solar photovoltaic "prosumers" has the potential to transform the 100-year-old centralized electric utility model into a more decentralized and interactive system. In some countries, it is now more cost-effective for households to produce their own power from PV than to purchase electricity from the grid. However, a prosumer "revolution" under which decentralized adoption of PV occurs on its own, in the absence of supportive policies or regulatory conditions, has not yet arrived. Self-consumption of solar PV is a growing trend globally, but its expansion remains within policy makers’ ability to control and develop.

  8. Human Driver Model for SmartAHS

    E-Print Network [OSTI]

    Delorme, Delphine; Song, Bongsob

    2001-01-01

    the Human Factors field (Rockwell 1988, Bhises et al.1986,Amsterdam, pp. 91-100. Rockwell, T. H. , (1988) Spare visual

  9. Climate Drivers of Spartina alterniflora Saltmarsh Production

    E-Print Network [OSTI]

    Pennings, Steven C.

    in and around the Altamaha river estuary on the coast of Georgia, USA. End of the year live biomass was assessed ecosystem services by fueling food webs with energy and by forming a critical part of the carbon cycle.uh.edu Ecosystems DOI: 10.1007/s10021-013-9732-6 Ó 2013 Springer Science+Business Media New York #12;and others 2000

  10. Cyclotrons as Drivers for Precision Neutrino Measurements

    E-Print Network [OSTI]

    Adelmann, A.

    As we enter the age of precision measurement in neutrino physics, improved flux sources are required. These must have a well defined flavor content with energies in ranges where backgrounds are low and cross-section ...

  11. WBG Gate Drivers for Power Modules

    Broader source: Energy.gov [DOE]

    2013 DOE Hydrogen and Fuel Cells Program and Vehicle Technologies Program Annual Merit Review and Peer Evaluation Meeting

  12. Fundamental Drivers of Pacific Northwest Power Markets

    E-Print Network [OSTI]

    , utilities, power marketers, investors, and others on wholesale electricity and natural gas markets. Experts Load Transmission Thermal Hydro Wind (2005) #12;Natural Gas Capacity 6 5,000 MW of Natural Gas;Natural Gas Power Plant Production is Significantly Down 2010 to 2012 13 #12;Mid C Peak Heat Rates 14

  13. The Jefferson lab FEL driver ERLs

    SciTech Connect (OSTI)

    Douglas, David R.; Tennant, Christopher D.

    2013-11-01

    Jefferson Lab has - for over a decade - been operating high power IR and UV FELs using CW energy recovering linacs based on DC photocathode electron sources and CEBAF SRF technology. These machines have unique combinations of beam quality, power, and operational flexibility, and thus offer significant opportunity for experiments that use low and medium energy (several tens - few hundreds of MeV) electron beams. We will describe the systems and detail their present and near-term (potential) performance. Recent internal-target analysis and validation testing will be discussed, and schemes for single- and two-pass fixed target operation described. An introduction to subsequent discussions of beam quality and upgrade paths to polarized operation/higher energy will be given.

  14. Raman accumulator as a fusion laser driver

    DOE Patents [OSTI]

    George, E.V.; Swingle, J.C.

    1982-03-31

    Apparatus for simultaneous laser pulse amplification and compression, using multiple pass Raman scattering in one Raman cell and pulse switchout from the optical cavity through use of a dichroic device associated with the Raman cell.

  15. Alternative Fuel Driver Training Companion Manual

    SciTech Connect (OSTI)

    Not Available

    2005-09-01

    Training manual serves as a companion to alternative fuel training presentations on the fueling and use of vehicles that run on compressed natural gas, biodiesel, E85, and propane.

  16. Fleet Services Program Policy Manual For Drivers

    E-Print Network [OSTI]

    Brown, Sally

    · Schedules vehicles for preventative maintenance · Repair services · Fuel, and car wash services for all

  17. Drivers of Commercial Building Operator Skills 

    E-Print Network [OSTI]

    Domanski, J.

    2011-01-01

    ? Managerial skills ? Market knowledge ? Building certifications ? Energy Star, LEED ? Industry resources 9 C&W TRAINING & DEVELOPMENT OPPORTUNITIES ? C&W Training and Support programs ? C&W Green Practice Policies ? LEED Green Associate and AP...

  18. Hydraulic Cooling Tower Driver- The Innovation 

    E-Print Network [OSTI]

    Dickerson, J. A.

    1987-01-01

    -drive eliminates these items from the drive train and puts the same electric motor HP at ground level close coupled to a hydraulic pump, filters, and oil reservoir. Hydraulic lines bring oil pressure to the hydraulic motor, which is more than 75% less weight than...

  19. ECOdriving - Widespread Implementation for Learner Drivers and...

    Open Energy Info (EERE)

    Topics: Best Practices Website: www.ecodrive.org Transport Toolkit Region(s): Europe Related Tools State Roles in Providing Affordable Mass Transport Services for...

  20. OMEGA Laser Drivers - Laboratory for Laser Energetics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefieldSulfateSciTechtail.Theory ofDid you notHeatMaRIEdioxideUser WorkEP Power Conditioning -

  1. TEAM 1 Drivers License.doc

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorking With LivermoreSustainable Landmimic keySystemssystemsoTE ConnectivityI

  2. Sandia National Laboratories: Pollution Prevention: Regulatory Drivers

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust, High-ThroughputUpcoming Release of thePrograms:Mode Stirred Chamber

  3. Alternative Fuel Driver Training Companion Manual

    Alternative Fuels and Advanced Vehicles Data Center [Office of Energy Efficiency and Renewable Energy (EERE)]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels Data Center Home Page onPropane Rolls onManual del vehículoU.S. Department

  4. Brief Narrative Description of Research, Teaching, and Service Interests Research: My research involves modeling time-to-event data using flowgraph models.

    E-Print Network [OSTI]

    Huzurbazar, Aparna V.

    for Project AIR FORCE. The main projects involved issues in fleet assessment and programmed depot maintenance, Statistical Inference, Survival Analysis and Logistic Regression, Linear Models, Multivariate Analysis

  5. Cytoplasmic polyadenylation and cytoplasmic polyadenylation element-dependent mRNA regulation are involved in Xenopus retinal axon development

    E-Print Network [OSTI]

    Lin, Andrew C; Tan, Chin Lik; Lin, Chien-Ling; Strochlic, Laure; Huang, Yi-Shuian; Richter, Joel D; Holt, Christine E

    2009-03-02

    ) RFP/RBM-transfected embryos have bright RFP-positive axons in the optic pathway projecting correctly to the tectum, while RFP/AA-transfected embryos do not. Scale bars: 65 ?m (A, B, M, N); 10 ?m (D, F, J, K); 5 ?m (I). Blue, DAPI; green, CPEB1-GFP... AcceCResearch article Cytoplasmic polyadenylation and cytoplasmic polyadenylation element-dependent mRNA regulation are involved in Xenopus retinal axon development Andrew C Lin1,3, Chin Lik Tan1,4, Chien-Ling Lin2, Laure Strochlic1,5, Yi- Shuian...

  6. Characterization of the ptr5{sup +} gene involved in nuclear mRNA export in fission yeast

    SciTech Connect (OSTI)

    Watanabe, Nobuyoshi; Ikeda, Terumasa; Mizuki, Fumitaka [Department of Biological Sciences, Graduate School of Science and Technology, Kumamoto University, Kurokami, Kumamoto 860-8555 (Japan)] [Department of Biological Sciences, Graduate School of Science and Technology, Kumamoto University, Kurokami, Kumamoto 860-8555 (Japan); Tani, Tokio, E-mail: ttani@sci.kumamoto-u.ac.jp [Department of Biological Sciences, Graduate School of Science and Technology, Kumamoto University, Kurokami, Kumamoto 860-8555 (Japan)] [Department of Biological Sciences, Graduate School of Science and Technology, Kumamoto University, Kurokami, Kumamoto 860-8555 (Japan)

    2012-02-03

    Highlights: Black-Right-Pointing-Pointer We cloned the ptr5{sup +} gene involved in nuclear mRNA export in fission yeast. Black-Right-Pointing-Pointer The ptr5{sup +} gene was found to encode nucleoporin 85 (Nup85). Black-Right-Pointing-Pointer Seh1p and Mlo3p are multi-copy suppressors for the ptr5 mutation. Black-Right-Pointing-Pointer Ptr5p/Nup85p functions in nuclear mRNA export through the mRNA export factor Rae1p. Black-Right-Pointing-Pointer Ptr5p/Nup85p interacts genetically with pre-mRNA splicing factors. -- Abstract: To analyze the mechanisms of mRNA export from the nucleus to the cytoplasm, we have isolated eleven mutants, ptr [poly(A){sup +} RNA transport] 1 to 11, which accumulate poly(A){sup +} RNA in the nucleus at a nonpermissive temperature in Schizosaccharomyces pombe. Of those, the ptr5-1 mutant shows dots- or a ring-like accumulation of poly(A){sup +} RNA at the nuclear periphery after shifting to the nonpermissive temperature. We cloned the ptr5{sup +} gene and found that it encodes a component of the nuclear pore complex (NPC), nucleoporin 85 (Nup85). The ptr5-1 mutant shows no defects in protein transport, suggesting the specific involvement of Ptr5p/Nup85p in nuclear mRNA export in S. pombe. We identified Seh1p, a nucleoporin interacting with Nup85p, an mRNA-binding protein Mlo3p, and Sac3p, a component of the TREX-2 complex involved in coupling of nuclear mRNA export with transcription, as multi-copy suppressors for the ptr5-1 mutation. In addition, we found that the ptr5-1 mutation is synthetically lethal with a mutation of the mRNA export factor Rae1p, and that the double mutant exaggerates defective nuclear mRNA export, suggesting that Ptr5p/Nup85p is involved in nuclear mRNA export through Rae1p. Interestingly, the ptr5-1 mutation also showed synthetic effects with several prp pre-mRNA splicing mutations, suggesting a functional linkage between the NPCs and the splicing apparatus in the yeast nucleus.

  7. Counting Problems involving Symmetry

    E-Print Network [OSTI]

    Donu Arapura

    2013-04-12

    Group theory can be applied to counting problems invloving symmetry. Here ... problem is to count the set of orbits H/S3. ... a partition of G. By corollary 3.10,.

  8. Counting Problems involving Symmetry*

    E-Print Network [OSTI]

    Group theory can be applied to counting problems invloving symmetry. Here ... problem is to count the set of orbits H/S3. .... a partition of G. By corollary 2.3,.

  9. Parent Involvement (Spanish) 

    E-Print Network [OSTI]

    Howard, Jeff W.

    2005-05-10

    Para que un programa de 4-Hh sea exitoso, debe contar con la participaci?n de los padres. Aunque los l?deres de 4-H y los agentes de Extensi?n pueden interesar a los j?venes en ser miembros, necesitan la buena voluntad de los padres y su apoyo para...?deres voluntarios, los agentes de Extensi?n y lo que los miembros del 4-H esperan. Cuando los padres participan solamente super- ficialmente y no se les informa sobre las actividades del club, se puede esperar poca cooperaci?n de ellos. Se debe informar a los...

  10. Commitment to Public Involvement

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room News PublicationsAuditsCluster Compatibilitydefault Sign In About | Careers |Create a

  11. TPA Public Involvement Survey

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorking With LivermoreSustainableDEPARTMENT OFEnergy Innovation

  12. Involvement & Outreach

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefieldSulfateSciTechtail.Theory ofDid you notHeat Pumps Heat PumpsfacilityviaGasforVendors »

  13. Involvement and Communication Committee.

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverseIMPACT EVALUATIONIntroducing the RichardBudget and Contracts Committee Chair 1

  14. Involvement and Communication Committee.

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverseIMPACT EVALUATIONIntroducing the RichardBudget and Contracts Committee Chair

  15. Involvement and Communication Committee.

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverseIMPACT EVALUATIONIntroducing the RichardBudget and Contracts Committee

  16. Involvement and Communication Committee.

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverseIMPACT EVALUATIONIntroducing the RichardBudget and Contracts CommitteeRiver

  17. Involvement and Communication Committee.

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverseIMPACT EVALUATIONIntroducing the RichardBudget and Contracts

  18. Genome-Wide Identification and 3D Modeling of Proteins involved in DNA Damage Recognition and Repair (Final Report)

    SciTech Connect (OSTI)

    Ruben A. Abagyan, PhD

    2004-04-15

    OAK-B135 DNA Damage Recognition and Repair (DDR and R) proteins play a critical role in cellular responses to low-dose radiation and are associated with cancer. the authors have performed a systematic, genome-wide computational analysis of genomic data for human genes involved in the DDR and R process. The significant achievements of this project include: (1) Construction of the computational pipeline for searching DDR and R genes, building and validation of 3D models of proteins involved in DDR and R; (2) Functional and structural annotation of the 3D models and generation of comprehensive lists of suggested knock-out mutations; (3) Important improvement of macromolecular docking technology and its application to predict the DNA-Protein complex conformation; (4) Development of a new algorithm for improved analysis of high-density oligonucleotide arrays for gene expression profiling; (5) Construction and maintenance of the DNA Damage Recognition and Repair Database; and (6) Producing 14 research papers (10 published and 4 in preparation).

  19. Genome-Wide Identification and 3D Modeling of Proteins involved in DNA Damage Recognition and Repair (Final Report)

    SciTech Connect (OSTI)

    Abagyan, Ruben; An, Jianghong

    2005-08-12

    DNA Damage Recognition and Repair (DDR&R) proteins play a critical role in cellular responses to low-dose radiation and are associated with cancer. We have performed a systematic, genome-wide computational analysis of genomic data for human genes involved in the DDR&R process. The significant achievements of this project include: 1) Construction of the computational pipeline for searching DDR&R genes, building and validation of 3D models of proteins involved in DDR&R; 2) Functional and structural annotation of the 3D models and generation of comprehensive lists of suggested knock-out mutations; and the development of a method to predict the effects of mutations. Large scale testing of technology to identify novel small binding pockets in protein structures leading to new DDRR inhibitor strategies 3) Improvements of macromolecular docking technology (see the CAPRI 1-3 and 4-5 results) 4) Development of a new algorithm for improved analysis of high-density oligonucleotide arrays for gene expression profiling; 5) Construction and maintenance of the DNA Damage Recognition and Repair Database; 6) Producing 15 research papers (12 published and 3 in preparation).

  20. Purely Mechanical Memristors: Perfect Massless Memory Resistors, the Missing Perfect Mass-Involving Memristor, and Massive Memristive Systems

    E-Print Network [OSTI]

    Sascha Vongehr

    2015-08-15

    We define a mechanical analog to the electrical basic circuit element M = d{\\phi}/dQ, namely the ideal mechanical memristance M = dp/dx; p is momentum. We then introduce a mechanical memory resistor which has M(x) independent of velocity v, so it is a perfect (= not-just-memristive) memristor, although its memristance does not crucially involve inert mass. It is practically realizable with a 1cm radius hollow sphere in heavy fuel oil with a temperature gradient. It has a pinched hysteretic loop that collapses at high frequency in the v versus p plot. The mechanical system clarifies the nature of memristor devices that can be hypothesized on grounds of physical symmetries. We hypothesize a missing mechanical perfect memristor, which must be crucially mass-involving (MI) precisely like the 1971 implied EM memristor device needs magnetism. We also construct MI memristive nano systems, which clarifies why perfect MI memristors and EM memristors are still missing and likely impossible.

  1. DOE Technical Standards List. Directory of DOE and contractor personnel involved in non-government standards activities

    SciTech Connect (OSTI)

    NONE

    1997-06-01

    This is a periodic report on the level of agency participation in non-Government standards activities. This technical standards list is intended to assist US Department of Energy (DOE) management and other personnel involved in the DOE technical Standards Program by identifying those participating individuals. The body of this document contains a listing of DOE employees and DOE contractors who have submitted a Record of Non-Government Standards Activity. Additional names were added from rosters supplied by non-Government standards bodies. Appendices to this document are provided to list the information by parent employment organization, by non-Government standards activity, and by the proper names of the non-Government standards organizations and committees.

  2. DNA rearrangement in human follicular lymphoma can involve the 5' or the 3' region of the bcl-2 gene

    SciTech Connect (OSTI)

    Tsujimoto, Y.; Bashir, M.M.; Givol, I.; Cossman, J.; Jaffe, E.; Croce, C.M.

    1987-03-01

    In most human lymphomas, the chromosome translocation t(14;18) occurs within two breakpoint clustering regions on chromosome 18, the major one at the 3' untranslated region of the bcl-2 gene and the minor one at 3' of the gene. Analysis of a panel of follicular lymphoma DNAs using probes for the first exon of the bcl-2 gene indicates that DNA rearrangements may also occur 5' to the involved bcl-2 gene. In this case the IgH locus and the bcl-2 gene are found in an order suggesting that an inversion also occurred during the translocation process. The coding region of the bcl-2 gene, however, are left intact in all cases of follicular lymphoma studied to date.

  3. Selection of potential IAEA inspection strategies involving cascade access at the Portsmouth Gas Centrifuge Enrichment Plant (GCEP)

    SciTech Connect (OSTI)

    Not Available

    1981-04-13

    This report has been prepared as a US contribution to Team 4 of the Hexapartite Safeguards Project. It provides to the Team 4 participants one example of an approach, which has been used in the United States, to developing a range of safeguards strategies involving differing degrees of access to cascade areas of centrifuge enrichment plants. Its purpose is to facilitate the work of other Hexapartite participants in completing Task II of Team 4's terms of reference. The scope of this report is limited to identifying safeguards approaches for the Portsmouth Gas Centrifuge Enrichment Plant (GCEP) which involve differing degrees of access to the cascade area. This report provides a method for selecting cascade access inspection strategies at GCEP which appear promising for more detailed evaluation. It is quite important to note, however, that the effectiveness and practicability of these strategies have not been established at the present. In addition, some strategies have been included on the basis of very preliminary calculations and considerations which have not been validated. Thus, some of these strategies may ultimately be rejected because they prove to be impracticable. Considerations of cost and the possible transfer of information and technology related to the production of enriched uranium will also be pertinent in considering the degrees and frequency of access to the cascade areas of centrifuge enrichment plants. This report describes the process for combining technical measures, implementation approaches and objectives to arrive at the total number of theoretically possible combinations. It then describes how these combinations may be reduced in a series of steps to a number that is more manageable for detailed evaluation. The process is shown schematically.

  4. Involvement of caspase-12-dependent apoptotic pathway in ionic radiocontrast urografin-induced renal tubular cell injury

    SciTech Connect (OSTI)

    Wu, Cheng Tien [Institute of Toxicology, College of Medicine, National Taiwan University, Taipei, Taiwan (China)] [Institute of Toxicology, College of Medicine, National Taiwan University, Taipei, Taiwan (China); Weng, Te I. [Department of Forensic Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan (China)] [Department of Forensic Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan (China); Chen, Li Ping [Department of Dentistry, Chang Gang Memorial Hospital, Chang Gang University, Taoyuan, Taiwan (China)] [Department of Dentistry, Chang Gang Memorial Hospital, Chang Gang University, Taoyuan, Taiwan (China); Chiang, Chih Kang [Department of Integrated Diagnostics and Therapeutics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan (China) [Department of Integrated Diagnostics and Therapeutics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan (China); Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan (China); Liu, Shing Hwa, E-mail: shinghwaliu@ntu.edu.tw [Institute of Toxicology, College of Medicine, National Taiwan University, Taipei, Taiwan (China); Department of Urology, National Taiwan University Hospital, Taipei, Taiwan (China)

    2013-01-01

    Contrast medium (CM) induces a direct toxic effect on renal tubular cells. This toxic effect subjects in the disorder of CM-induced nephropathy. Our previous work has demonstrated that CM shows to activate the endoplasmic reticulum (ER)-related adaptive unfolding protein response (UPR) activators. Glucose-regulated protein 78 (GRP78)/eukaryotic initiation factor 2? (eIF2?)-related pathways play a protective role during the urografin (an ionic CM)-induced renal tubular injury. However, the involvement of ER stress-related apoptotic signals in the urografin-induced renal tubular cell injury remains unclear. Here, we examined by the in vivo and in vitro experiments to explore whether ER stress-regulated pro-apoptotic activators participate in urografin-induced renal injury. Urografin induced renal tubular dilation, tubular cells detachment, and necrosis in the kidneys of rats. The tubular apoptosis, ER stress-related pro-apoptotic transcriptional factors, and kidney injury marker-1 (kim-1) were also conspicuously up-regulated in urografin-treated rats. Furthermore, treatment of normal rat kidney (NRK)-52E tubular cells with urografin augmented the expressions of activating transcription factor-6 (ATF-6), C/EBP homologous protein (CHOP), Bax, caspase-12, JNK, and inositol-requiring enzyme (IRE) 1 signals. Urografin-induced renal tubular cell apoptosis was not reversed by the inhibitors of ATF-6, JNK signals or CHOP siRNA transfection, but it could be partially reversed by the inhibitor of caspase-12. Taken together, the present results and our previous findings suggest that exposure of CM/urografin activates the ER stress-regulated survival- and apoptosis-related signaling pathways in renal tubular cells. Caspase-12-dependent apoptotic pathway may be partially involved in the urografin-induced nephropathy. -- Highlights: ? Ionic contrast medium-urografin induces renal tubular cell apoptosis. ? Urografin induces the ER stress-regulated survival and apoptosis signals. ? Caspase-12 signaling participates in urografin-induced renal cell apoptosis.

  5. After the Disaster: Considerations for Older Adults 

    E-Print Network [OSTI]

    Crocker, Andrew

    2005-10-07

    that monthly payments get to beneficiaries and that other vital Social Security services are provided. If the United States Postal Service (USPS) suspends mail service in areas affected by a disaster, paper checks cannot be delivered. But the USPS usually... establishes temporary mail delivery stations where you can pick up your Social Security check. To help prevent identity fraud, USPS will ask you for a photo ID. If Social Security benefits are deposited directly into your bank account you will continue...

  6. Health of Older Californians: County Data Book

    E-Print Network [OSTI]

    Wallace, Steven P.; Pourat, Nadereh; Enriquez-Haass, Vilma; Sripipatana, Alek

    2003-01-01

    San Joaquin, Stanislaus, Tulare Central Coast Counties:Kings County (Kings and Tulare Counties combined) LakeCounty (see Lassen County) Tulare County (see Kings County)

  7. Trends in the Health of Older Californians

    E-Print Network [OSTI]

    Wallace, Steven P.; Lee, Jennifer H.; Jawad, May Aydin

    2008-01-01

    n Luis Obispo Fresno Inyo Tulare Kings to ni Be Kern Sa ntaSan Joaquin Stanislaus Tulare UCLA Center for Health PolicySan Joaquin Stanislaus Tulare No Colonoscopy ER Visits 12 or

  8. OLDER PEOPLE AND THEIR WINTER WARMTH BEHAVIOURS

    E-Print Network [OSTI]

    Jones, Peter JS

    . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .26 9 . Warmth out of the House they kept warm during winter and the various contextual factors influencing these choices. The rationale the extent to which winter warmth practices were common across the generational cohort irrespective of wealth

  9. Young and Older Adults’ Reading of Distracters

    E-Print Network [OSTI]

    Kemper, Susan; McDowd, Joan; Metcalf, Kim; Liu, Chiung-Ju

    2008-05-01

    occurrences per million words (Francis & Kucera, 1967). Four-word distracters formed meaningful phrases. For example, the phrase “the very angry taxpayer” was inserted as a distracter into the sentence “The postman opened the package to inspect its... contents” prior to the target word “contents.” The 4-word distracter phrases were then shortened to 2-word distracters, e.g., “angry taxpayer,” and to 1-word distracters, e.g., “taxpayer.” The final step was to make sure that all distracters did...

  10. Older Public Presentations | Critical Materials Institute

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration wouldMass mapSpeeding access toOctober 1996 -Workers'OfficialSanFoot)Oklahoma99

  11. Novel mechanism for scavenging of hypochlorite involving a periplasmic methionine-rich peptide and methionine sulfoxide reductase

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Melnyk, Ryan A.; Youngblut, Matthew D.; Clark, Iain C.; Carlson, Hans K.; Wetmore, Kelly M.; Price, Morgan N.; Lavarone, Anthony T.; Deutschbauer, Adam M.; Arkin, Adam P.; Coates, John D.

    2015-05-12

    Reactive chlorine species (RCS) defense mechanisms are important for bacterial fitness in diverse environments. In addition to the anthropogenic use of RCS in the form of bleach, these compounds are also produced naturally through photochemical reactions of natural organic matter and in vivo by the mammalian immune system in response to invading microorganisms. To gain insight into bacterial RCS defense mechanisms, we investigated Azospira suillum strain PS, which produces periplasmic RCS as an intermediate of perchlorate respiration. Our studies identified an RCS response involving an RCS stress-sensing sigma/anti-sigma factor system (SigF/NrsF), a soluble hypochlorite-scavenging methionine-rich periplasmic protein (MrpX), and amore »putative periplasmic methionine sulfoxide reductase (YedY1). We investigated the underlying mechanism by phenotypic characterization of appropriate gene deletions, chemogenomic profiling of barcoded transposon pools, transcriptome sequencing, and biochemical assessment of methionine oxidation. Our results demonstrated that SigF was specifically activated by RCS and initiated the transcription of a small regulon centering around yedY1 and mrpX. A yedY1 paralog (yedY2) was found to have a similar fitness to yedY1 despite not being regulated by SigF. Markerless deletions of yedY2 confirmed its synergy with the SigF regulon. MrpX was strongly induced and rapidly oxidized by RCS, especially hypochlorite. Our results suggest a mechanism involving hypochlorite scavenging by sacrificial oxidation of the MrpX in the periplasm. Reduced MrpX is regenerated by the YedY methionine sulfoxide reductase activity. The phylogenomic distribution of this system revealed conservation in several Proteobacteria of clinical importance, including uropathogenic Escherichia coli and Brucella spp., implying a putative role in immune response evasion in vivo. In addition, bacteria are often stressed in the environment by reactive chlorine species (RCS) of either anthropogenic or natural origin, but little is known of the defense mechanisms they have evolved. Using a microorganism that generates RCS internally as part of its respiratory process allowed us to uncover a novel defense mechanism based on RCS scavenging by reductive reaction with a sacrificial methionine-rich peptide and redox recycling through a methionine sulfoxide reductase. This system is conserved in a broad diversity of organisms, including some of clinical importance, invoking a possible important role in innate immune system evasion.« less

  12. Accurate Computer Simulation of Phase Equilibrium for Complex Fluid Mixtures. Application to Binaries Involving Isobutene, Methanol, Methyl tert-Butyl Ether, and

    E-Print Network [OSTI]

    Lisal, Martin

    to Binaries Involving Isobutene, Methanol, Methyl tert-Butyl Ether, and n-Butane Martin Li´sal,*,, William R + methyl tert-butyl ether (MTBE) and the binaries formed by methanol with isobutene, MTBE, and n

  13. University of Twente Scientific Integrity Complaints Procedure Within the University of Twente all persons involved in education and research have a personal

    E-Print Network [OSTI]

    Boucherie, Richard J.

    (the suspicion of) a violation of scientific integrity by an employee Complainant: A person whoUniversity of Twente Scientific Integrity Complaints Procedure Preamble Within the University of Twente all persons involved in education and research have a personal responsibility

  14. Visible light stimulating dual-wavelength emission and O vacancy involved energy transfer behavior in luminescence for coaxial nanocable arrays

    SciTech Connect (OSTI)

    Yang, Lei, E-mail: nanoyang@qq.com [College of Materials Science and Engineering, Hunan University, Changsha 410082 (China); Hunan Province Key Laboratory for Spray Deposition Technology and Application, Hunan University, Changsha 410082 (China); Dong, Jiazhang; Jiang, Zhongcheng [College of Materials Science and Engineering, Hunan University, Changsha 410082 (China); Pan, Anlian; Zhuang, Xiujuan [Key Laboratory for Micro-Nano Physics and Technology of Hunan Province, Hunan University, Changsha 410082 (China)

    2014-06-14

    We report a strategy to investigate O vacancy (V{sub O}) involved energy transfer and dual-wavelength yellow emission in coaxial nanocable. By electric field deposition and subsequent sol-gel template approach, ZnO:Tb/Y{sub 2}O{sub 3}:Eu coaxial nanocable arrays are synthesized. After visible light excitation, system is promoted to O vacancy charge transfer state of V{sub O}(0/+). In the following cross relaxation, energy transfer from V{sub O} to the excitation energy level of Tb{sup 3+} in ZnO:Tb core area. While in Y{sub 2}O{sub 3}:Eu shell area, energy transfer to the excitation energy level of Eu{sup 3+}. Subsequently, dual-wavelength emission is observed. By constructing nanocable with dual-wavelength emission, yellow luminescence is obtained. Adjust doping concentration of Eu{sup 3+} or Tb{sup 3+} in the range of 0.01–0.05, chromaticity coordinates of ZnO:Tb/Y{sub 2}O{sub 3}:Eu nanocable stably stays at yellow region in color space except ZnO:Tb{sub 0.01}/Y{sub 2}O{sub 3}:Eu{sub 0.01}. As Vo states act as media in energy transfer process in nanocablers, visible light can stimulate dual-wavelength emissions. Yellow luminescent nanocable arrays will have great applications in light-emitting diode luminescence.

  15. Bottomonium spectroscopy and radiative transitions involving the chi_bJ(1P,2P) states at BABAR

    E-Print Network [OSTI]

    J. P. Lees; for the BABAR Collaboration

    2014-10-16

    We use $(121\\pm1)$ million $\\Upsilon(3S)$ and $(98\\pm1)$ million $\\Upsilon(2S)$ mesons recorded by the BABAR detector at the PEP-II $e^+e^-$ collider at SLAC to perform a study of radiative transitions involving the $\\chi_{b\\mathrm{J}}(1P,2P)$ states in exclusive decays with $\\mu^+\\mu^-\\gamma\\gamma$ final states. We reconstruct twelve channels in four cascades using two complementary methods. In the first we identify both signal photon candidates in the Electromagnetic Calorimeter (EMC), employ a calorimeter timing-based technique to reduce backgrounds, and determine branching-ratio products and fine mass splittings. These results include the best observational significance yet for the $\\chi_{b0}(2P)\\rightarrow\\gamma\\Upsilon(2S)$ and $\\chi_{b0}(1P)\\rightarrow\\gamma\\Upsilon(1S)$ transitions. In the second method, we identify one photon candidate in the EMC and one which has converted into an $e^+e^-$ pair due to interaction with detector material, and we measure absolute product branching fractions. This method is particularly useful for measuring $\\Upsilon(3S)\\rightarrow\\gamma\\chi_{b1,2}(1P)$ decays. Additionally, we provide the most up-to-date derived branching fractions, matrix elements and mass splittings for $\\chi_b$ transitions in the bottomonium system. Using a new technique, we also measure the two lowest-order spin-dependent coefficients in the nonrelativistic QCD Hamiltonian.

  16. G-protein-coupled estrogen receptor 1 is involved in brain development during zebrafish (Danio rerio) embryogenesis

    SciTech Connect (OSTI)

    Shi, Yanan; Liu, Xiaochun; Zhu, Pei; Li, Jianzhen; Sham, Kathy W.Y.; Cheng, Shuk Han; Li, Shuisheng; Zhang, Yong; Cheng, Christopher H.K.; Lin, Haoran; College of Ocean, Hainan University, Haikou 570228, Hainan

    2013-05-24

    Highlights: •The Gper expression was detected in the developing brain of zebrafish. •Gper morpholino knockdown induced apoptosis of brain cells. •Gper morpholino knockdown reduced expression in neuron markers. •Zebrafish Gper may be involved in neuronal development. -- Abstract: G-protein-coupled estrogen receptor 1 (Gper, formerly known as GPR30) is found to be a trophic and protective factor in mediating action of estrogen in adult brain, while its role in developing brain remains to be elucidated. Here we present the expression pattern of Gper and its functions during embryogenesis in zebrafish. Both the mRNA and protein of Gper were detected throughout embryogenesis. Whole mount in situ hybridization (WISH) revealed a wide distribution of gper mRNAs in various regions of the developing brain. Gper knockdown by specific morpholinos resulted in growth retardation in embryos and morphological defects in the developing brain. In addition, induced apoptosis, decreased proliferation of the brain cells and maldevelopment of sensory and motor neurons were also found in the morphants. Our results provide novel insights into Gper functions in the developing brain, revealing that Gper can maintain the survival of the brain cells, and formation and/or differentiation of the sensory and motor neurons.

  17. Evidence of extra-telomeric effects of hTERT and its regulation involving a feedback loop

    SciTech Connect (OSTI)

    Lai, Serene R.; Cunningham, Amanda P.; Huynh, Vu Q.; Andrews, Lucy G.; Tollefsbol, Trygve O. . E-mail: trygve@uab.edu

    2007-01-15

    The human telomerase reverse transcriptase (hTERT) is the catalytic subunit of the enzyme telomerase which is responsible for telomeric maintenance and extension. Using RNA interference to knock down hTERT mRNA expression, we provide evidence that hTERT exerts extra-telomeric effects on the cell cycle and on its own regulatory proteins, specifically: p53 and p21. We tested our hypothesis that hTERT regulates its own expression through effects on upstream regulatory genes using transformed human embryonic kidney (HEK 293) cells, p53 and p16 {sup INK4a} null human ovarian cancer SKOV-3 cells, and p53-null MDA-MB-157 human mammary cancer cells. In HEK 293 cells, hTERT knockdown resulted in elevated p53 and p21 transcription and a decrease in cellular proliferation. Similar results were observed in the MDA-MB-157 cell line where p21 was upregulated, correlating with cell growth inhibition. In contrast, we observed a decrease in expression of p21 in SKOV-3 cells with hTERT knockdown and cell growth appeared to be unaffected. These findings suggest that hTERT may be involved in a feedback loop system, thereby playing a role in its own regulation.

  18. H2-M polymorphism in mice susceptible to collagen-induced arthritis involves the peptide binding groove

    SciTech Connect (OSTI)

    Walter, W.; Loos, M.; Maeurer, M.J.

    1996-12-31

    The ability to develop type II collagen (CII)-induced arthritis (CIA) in mice is associated with the major histocompatibility I-A gene and with as yet poorly defined regulatory molecules of the major histocompatibility complex (MHC) class II antigen processing and presentation pathway. H2-M molecules are thought to be involved in the loading of antigenic peptides into the MHC class II binding cleft. We sequenced H2-Ma, H2-Mb1, and H2-Mb2 genes from CIA-susceptible and -resistant mouse strains and identified four different Ma and Mb2 alleles, and three different Mb1 alleles defined by polymorphic residues within the predicted peptide binding groove. Most CIA-resistant mouse strains share common Ma, Mb1, and Mb2 alleles. In contrast, H2-M alleles designated Ma-III, Ma-IV, Mb1-III, and Mb2-IV could be exclusively identified in the CIA-susceptible H2{sup r} and H2{sup q} haplotypes, suggesting that allelic H2-M molecules may modulate the composition of different CII peptides loaded onto MHC class II molecules, presumably presenting {open_quotes}arthritogenic{close_quotes} epitopes to T lymphocytes. 42 refs., 4 figs., 3 tabs.

  19. Science Drivers for Con-XScience Drivers for Con-X Presented by

    E-Print Network [OSTI]

    Garcia, Michael

    and their effect on galaxy formation Dark Matter and Dark Energy Use clusters of galaxies to trace the locations of Dark Matter and as independent probes to constrain the amount and evolution of Dark Energy Search for the missing baryonic matter in the Cosmic Web Cycles of Matter and Energy Study dynamics of Cosmic Feedback

  20. Yes-associated protein homolog, YAP-1, is involved in the thermotolerance and aging in the nematode Caenorhabditis elegans

    SciTech Connect (OSTI)

    Iwasa, Hiroaki [Department of Medical Biochemistry, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo 113-8519 (Japan); Maimaiti, Sainawaer [Department of Medical Biochemistry, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo 113-8519 (Japan); Department of Psychotherapy, The Fourth People's Hospital of Urumqi, Urumqi 830000 (China); Kuroyanagi, Hidehito [Laboratory of Gene Expression, Graduate School of Biomedical Science, Tokyo Medical and Dental University, Tokyo 113-8519 (Japan); Kawano, Shodai; Inami, Kazutoshi; Timalsina, Shikshya; Ikeda, Mitsunobu; Nakagawa, Kentaro [Department of Medical Biochemistry, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo 113-8519 (Japan); Hata, Yutaka, E-mail: yuhammch@tmd.ac.jp [Department of Medical Biochemistry, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo 113-8519 (Japan)

    2013-04-15

    The mammalian Hippo pathway comprises mammalian Ste20-like kinases (MST1/2) and large tumor suppressor kinases (LATS1/2). LATS1/2, which are activated by MST1/2, phosphorylate a transcriptional co-activator, yes-associated protein (YAP), and induce the recruitment of YAP by 14-3-3 to cytoplasm, so that the TEAD-dependent gene transcriptions are turned off. Although the core components of the Hippo pathway are well conserved in metazoans, it has been discussed that Caenorhabditis elegans lacks YAP ortholog, we found that F13E6.4 gene encodes a protein that shows sequence similarities to YAP in the N-terminal TEAD-binding domain and in the WW domain. We designated this gene as yap-1. YAP-1 is widely expressed in various cells such as epithelial cells, muscles, hypodermal cells, gonadal sheath cells, spermatheca, and hypodermal cells. YAP-1 is distributed in cytoplasm and nuclei. wts-1 (LATS ortholog) and ftt-2 (14-3-3 ortholog) knockdowns cause nuclear accumulation of YAP-1, supporting that the subcellular localization of YAP-1 is regulated in a similar way as that of YAP. Heat shock also causes the nuclear accumulation of YAP-1 but after heat shock, YAP-1 translocates to cytoplasm. Knockdowns of DAF-21 (HSP90 ortholog) and HSF-1block the nuclear export of YAP-1 during this recovery. YAP-1 overexpression is beneficial for thermotolerance, whereas YAP-1 hyperactivity induced by wts-1 and ftt-2 knockdowns is deleterious on thermal response and yap-1 deficiency promotes health aging. In short, YAP-1 partially shares basal characters with mammalian YAP and plays a role in thermal stress response and healthy aging. - Highlights: ? We named Caenorhabditis elegans F13E6.4 gene yap-1 as a putative YAP homolog. ? The localization of YAP-1 is regulated by WTS-1 and FTT-2. ? YAP-1 is involved in healthy aging and thermosensitivity.