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Note: This page contains sample records for the topic "involvement involvement involvement" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
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1

Parent Involvement  

E-Print Network [OSTI]

To be successful, a 4-H program must have parent involvement. Although 4-H leaders and Extension agents may interest young people in becoming members, they need the parents' goodwill and support to keep them interested, enthusiastic and active. Here...

Howard, Jeff W.

2005-05-10T23:59:59.000Z

2

Commitment to Public Involvement  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Create a Sustainable Future Commitment to Public Involvement Commitment to Public Involvement LANL is commited to our neighbors August 1, 2013 Lab Director McMillan talks with...

3

Involvement and Communication Committee.  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Public Involvement and Communication Committee Chair 1 : Liz Mattson 4 , Alternate Vice Chair 1 : Ken Niles 4 , Member Committee Members 2 : Shelley Cimon Peggy Maze Johnson Rob...

4

ASI Student Involvement Outcomes ASI Student Involvement Outcomes  

E-Print Network [OSTI]

ASI Student Involvement Outcomes ASI Student Involvement Outcomes A student involved in the activities, programs, and services of the Associated Students, CSUF, Inc. develops and demonstrates achievement in the following (adopted from the University of Minnesota Student Success Outcomes

de Lijser, Peter

5

STUDENT EMPLOYMENT Student Involvement Outcomes  

E-Print Network [OSTI]

STUDENT EMPLOYMENT Student Involvement Outcomes reflective assessment High impact practices ASSOCIATED STUDENTS, CSUF, INC. Committed TO ON-CAMPUS ENGAGEMENT · SUPPORTING STUDENT SUCCESS · UNIFYING THE STUDENT VOICE · FOSTERING TITAN PRIDE #12;Organizational Structure Associated Students, CSUF, Inc. (ASI

de Lijser, Peter

6

Studies involving low protein broiler diets  

E-Print Network [OSTI]

STUDIES INVOLVING L(% PROTEIN BROILER DIETS A Thesis by David Palmer Parkin Submitted to the Graduate College of Texas A&M University in partial fulfillment of the requirement for the degree of MASTER OF SCIENCE May 1971 Major Subject...: Poultry Science STUDIES INVOLVING LS& PROTEIN BROILER DIETS A Thesis by David Palmer Parkin Approved as to style and content by: (Chairman of Commit e) ead of. Departmen Me er) (Member) (Memb ) May 1971 ABSTRACT Studies Involving Low Protein...

Parkin, David Palmer

1971-01-01T23:59:59.000Z

7

Factors Involved in Search Dog Training  

E-Print Network [OSTI]

involved in training competent search dogs. Obedience training methods, age training was initiated, previous handler canine training experience, and handler perception and emotional attachment to their search dog were examined through a sixty-six question...

Alexander, Michael B.

2010-07-14T23:59:59.000Z

8

Fire Classifications Fires involving the ordinary  

E-Print Network [OSTI]

, plastics, etc. Fires involving combustible or flammable liquids such as gasoline, kerosene, oils, grease is protected by various devices such as smoke detectors, sprinkler systems, and manual fire alarm pull stations. Manual pull stations are strategically located throughout the University. Usually located by each exit

Jia, Songtao

9

Production of Meson Pairs Involving $L \  

E-Print Network [OSTI]

We present a formalism for studying the exclusive production or decay of mesons with any value of the internal orbital angular momentum L. As an application, we discuss the production of meson pairs (involving tensor and pseudotensor mesons) in photon-photon collisions.

Houra-Yaou, L; Parisi, J; Murgia, F; Hansson, J

1997-01-01T23:59:59.000Z

10

Environmental science and ecology involve studies  

E-Print Network [OSTI]

Environmental science and ecology involve studies of the biosphere, hydro- sphere, and lithosphere in environmental science is conducted on spatial scales varying from a single algal cell to the Earth as a whole's environmental scientists require investigation by an interdisciplinary team, including members from several

Christensen, Dan

11

Regulation of the genes involved in nitrification.  

SciTech Connect (OSTI)

OAK-B135 This project focuses on the characterization of the regulation of the genes involved in nitrification in the bacterium Nitrosomonas europaea. The key genes in the nitrification pathway, amo and hao, are present in multiple copies in the genome. The promoters for these genes were identified and characterized. It was shown that there were some differences in the transcriptional regulation of the copies of these genes.

Arp, D.J.; Sayavedra-Soto, L.A.

2003-08-14T23:59:59.000Z

12

Community Involvement | Y-12 National Security Complex  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsruc DocumentationP-Series to User Group and UserofProteinNews CommunicationsInvolvement Community

13

Community Involvement and Making a Difference  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation Proposed New SubstationCleanCommunity Involvement and Making a Difference Community

14

Choice, involvement and illusory control 1 Running head: CHOICE, INVOLVEMENT AND ILLUSORY CONTROL  

E-Print Network [OSTI]

, which triggers the (quasi-)immediate resolution of the gamble (e.g., spinning the wheel, throwing the dice, picking the ball from the urn).1 Choice and Involvement are orthogonal dimensions of the gambling

Boyer, Edmond

15

Worker Involvement Improves Safety at Hanford Site's Plutonium...  

Broader source: Energy.gov (indexed) [DOE]

Worker Involvement Improves Safety at Hanford Site's Plutonium Finishing Plant Worker Involvement Improves Safety at Hanford Site's Plutonium Finishing Plant May 29, 2014 - 12:00pm...

16

Apolipoprotein gene involved in lipid metabolism  

DOE Patents [OSTI]

Methods and materials for studying the effects of a newly identified human gene, APOAV, and the corresponding mouse gene apoAV. The sequences of the genes are given, and transgenic animals which either contain the gene or have the endogenous gene knocked out are described. In addition, single nucleotide polymorphisms (SNPs) in the gene are described and characterized. It is demonstrated that certain SNPs are associated with diseases involving lipids and triglycerides and other metabolic diseases. These SNPs may be used alone or with SNPs from other genes to study individual risk factors. Methods for intervention in lipid diseases, including the screening of drugs to treat lipid-related or diabetic diseases are also disclosed.

Rubin, Edward (Berkeley, CA); Pennacchio, Len A. (Sebastopol, CA)

2007-07-03T23:59:59.000Z

17

Genomic Aspects of Research Involving Polyploid Plants  

SciTech Connect (OSTI)

Almost all extant plant species have spontaneously doubled their genomes at least once in their evolutionary histories, resulting in polyploidy which provided a rich genomic resource for evolutionary processes. Moreover, superior polyploid clones have been created during the process of crop domestication. Polyploid plants generated by evolutionary processes and/or crop domestication have been the intentional or serendipitous focus of research dealing with the dynamics and consequences of genome evolution. One of the new trends in genomics research is to create synthetic polyploid plants which provide materials for studying the initial genomic changes/responses immediately after polyploid formation. Polyploid plants are also used in functional genomics research to study gene expression in a complex genomic background. In this review, we summarize the recent progress in genomics research involving ancient, young, and synthetic polyploid plants, with a focus on genome size evolution, genomics diversity, genomic rearrangement, genetic and epigenetic changes in duplicated genes, gene discovery, and comparative genomics. Implications on plant sciences including evolution, functional genomics, and plant breeding are presented. It is anticipated that polyploids will be a regular subject of genomics research in the foreseeable future as the rapid advances in DNA sequencing technology create unprecedented opportunities for discovering and monitoring genomic and transcriptomic changes in polyploid plants. The fast accumulation of knowledge on polyploid formation, maintenance, and divergence at whole-genome and subgenome levels will not only help plant biologists understand how plants have evolved and diversified, but also assist plant breeders in designing new strategies for crop improvement.

Yang, Xiaohan [ORNL; Ye, Chuyu [ORNL; Tschaplinski, Timothy J [ORNL; Wullschleger, Stan D [ORNL; Tuskan, Gerald A [ORNL

2011-01-01T23:59:59.000Z

18

A successful effort to involve stakeholders in a facility siting decision using LIPS with stakeholder involvement  

SciTech Connect (OSTI)

Local public opposition to federal bureaucratic decisions has resulted in public agencies rethinking the role of stakeholders in decision making. Efforts to include stakeholders directly in the decision-making process are on the increase. Unfortunately, many attempts to involve members of the public in decisions involving complex technical issues have failed. A key problem has been defining a meaningful role for the public in the process of arriving at a technical decision. This paper describes a successful effort by Sandia National Laboratories (SNL) in New Mexico to involve stakeholders in an important technical decision associated with its Environmental Restoration (ER) Project. The decision was where to locate a Corrective Action Management Unit (CAMU), a facility intended to consolidate and store wastes generated from the cleanup of hazardous waste sites. A formal priority setting process known as the Laboratory Integration Prioritization System (LIPS) was adapted to provide an approach for involving the public. Although rarely applied to stakeholder participation, the LIPS process proved surprisingly effective. It produced a consensus over a selected site and enhanced public trust and understanding of Project activities.

Merkhofer, L. [Applied Decision Analysis, Inc., Menlo Park, CA (United States); Conway, R. [Sandia National Labs., Albuquerque, NM (United States); Anderson, B. [Los Alamos National Lab., NM (United States)

1995-12-31T23:59:59.000Z

19

Public involvement in radioactive waste management decisions  

SciTech Connect (OSTI)

Current repository siting efforts focus on Yucca Mountain, Nevada, where DOE`s Office of Civilian Radioactive Waste Management (OCRWM) is conducting exploratory studies to determine if the site is suitable. The state of Nevada has resisted these efforts: it has denied permits, brought suit against DOE, and publicly denounced the federal government`s decision to study Yucca Mountain. The state`s opposition reflects public opinion in Nevada, and has considerably slowed DOE`s progress in studying the site. The Yucca Mountain controversy demonstrates the importance of understanding public attitudes and their potential influence as DOE develops a program to manage radioactive waste. The strength and nature of Nevada`s opposition -- its ability to thwart if not outright derail DOE`s activities -- indicate a need to develop alternative methods for making decisions that affect the public. This report analyzes public participation as a key component of this openness, one that provides a means of garnering acceptance of, or reducing public opposition to, DOE`s radioactive waste management activities, including facility siting and transportation. The first section, Public Perceptions: Attitudes, Trust, and Theory, reviews the risk-perception literature to identify how the public perceives the risks associated with radioactivity. DOE and the Public discusses DOE`s low level of credibility among the general public as the product, in part, of the department`s past actions. This section looks at the three components of the radioactive waste management program -- disposal, storage, and transportation -- and the different ways DOE has approached the problem of public confidence in each case. Midwestern Radioactive Waste Management Histories focuses on selected Midwestern facility-siting and transportation activities involving radioactive materials.

NONE

1994-04-01T23:59:59.000Z

20

An analysis of factors contributing to train-involved crashes  

E-Print Network [OSTI]

. Crashes involving trains and vehicles are a significant safety problem in Texas each year. This research attempts to identify and analyze contributing factors to train-involved accidents in Texas. Three years of accident data (1328 total accidents) were...

Cooner, Scott Allen

1995-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "involvement involvement involvement" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


21

FOIASI - Special Inquiry Review of Allegations InvolvingPotentialMisc...  

Office of Environmental Management (EM)

Office of Environmental Management. The allegations involved potential violations of political activity restrictions, lack of impartiality in performing official duties, misuse of...

22

active user involvement: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

architecture. DBS was implemented on the Nano-Threads Programming Model (NPM) as part of NANOS, a large-scale project involving the development of a runtime...

23

activity involving yb-1: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

24

adenylyl cyclase involved: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

25

antigens predominant involvement: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

26

aedes aegypti involvement: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

27

adenosinergic system involvement: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

28

adjuvant involved field: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

29

alternaria alternata involves: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

30

antinociception involves endogenous: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

31

INVOLVED IN DE NOVO 2-containing complex involved in RNA-directed DNA methylation in Arabidopsis  

SciTech Connect (OSTI)

At least three pathways control maintenance of DNA cytosine methylation in Arabidopsis thaliana. However, the RNA-directed DNA methylation (RdDM) pathway is solely responsible for establishment of this silencing mark. We previously described INVOLVED IN DE NOVO 2 (IDN2) as being an RNA-binding RdDM component that is required for DNA methylation establishment. In this study, we describe the discovery of two partially redundant proteins that are paralogous to IDN2 and that form a stable complex with IDN2 in vivo. Null mutations in both genes, termed IDN2-LIKE 1 and IDN2-LIKE 2 (IDNL1 and IDNL2), result in a phenotype that mirrors, but does not further enhance, the idn2 mutant phenotype. Genetic analysis suggests that this complex acts in a step in the downstream portion of the RdDM pathway. We also have performed structural analysis showing that the IDN2 XS domain adopts an RNA recognition motif (RRM) fold. Finally, genome-wide DNA methylation and expression analysis confirms the placement of the IDN proteins in an RdDM pathway that affects DNA methylation and transcriptional control at many sites in the genome. Results from this study identify and describe two unique components of the RdDM machinery, adding to our understanding of DNA methylation control in the Arabidopsis genome.

Ausin, Israel; Greenberg, Maxim V.C.; Simanshu, Dhirendra K.; Hale, Christopher J.; Vashisht, Ajay A.; Simon, Stacey A.; Lee, Tzuu-fen; Feng, Suhua; Espaola, Sophia D.; Meyers, Blake C.; Wohlschlegel, James A.; Patel, Dinshaw J.; Jacobsen, Steven E. (UCLA); (MSKCC); (Delaware)

2012-10-23T23:59:59.000Z

32

LESSONS LEARNED FROM A LANDFILL SLOPE FAILURE INVOLVING  

E-Print Network [OSTI]

LESSONS LEARNED FROM A LANDFILL SLOPE FAILURE INVOLVING GEOSYTNTHETICS Virginia L. Wilson: Geosynthetics: Lessons Learned from Failures International Geosynthetics Society editors J.P. Giroud, K.L. Soderman and G.P. Raymond November 12, 1998 #12;LESSONS LEARNED FROM A LANDFILL SLOPE FAILURE INVOLVING

33

Lessons Learned from Failures Involving Geofoam in Roads and Embankments  

E-Print Network [OSTI]

Lessons Learned from Failures Involving Geofoam in Roads and Embankments Manhattan College Research July 1999) #12;Lessons Learned from Failures Involving Geofoam in Roads and Embankments Manhattan College Research Report No. CE/GE-99-1 ii This page intentionally left blank. #12;Lessons Learned from

Horvath, John S.

34

EXISTENCE OF SOLUTIONS TO A NONLINEAR PROBLEM INVOLVING ISOTROPIC DEFORMATIONS  

E-Print Network [OSTI]

EXISTENCE OF SOLUTIONS TO A NONLINEAR PROBLEM INVOLVING ISOTROPIC DEFORMATIONS ANA CRISTINA BARROSO manuscript, published in "Journal of Nonlinear Systems and Applications (2010) ?" #12;2 ANA CRISTINA BARROSO

Paris-Sud XI, Université de

35

Cognitive Control Involved in Overcoming Prepotent Response Tendencies and  

E-Print Network [OSTI]

Cognitive Control Involved in Overcoming Prepotent Response Tendencies and Switching Between Tasks, USA, 2 Center for the Neural Basis of Cognition, Pittsburgh, PA 15213, USA and 3 University, parietal, task switching, conflict effect, preparation Introduction Cognitive control comprises several

Wainwright, Peter C.

36

Cost Transfers Involving Sponsored Projects Directives and Procedures  

E-Print Network [OSTI]

Cost Transfers Involving Sponsored Projects Directives and Procedures Responsible Office: Office.................................................................................................................2 2. Project Management to a project when an award arrived after the budget period which would have allowed the transactions

Jawitz, James W.

37

An exploration of meaningful involvement in ropes course programs  

E-Print Network [OSTI]

Ropes course programs provide numerous benefits but what makes programs effective has been unclear. The purpose of the study was to: 1) determine if there was a measurable difference in meaningful involvement between the Challenge by Choice (CbC...

Haras, Katryna Stephanie

2004-09-30T23:59:59.000Z

38

Electromagnetic Inverse Problems Involving Distributions of Dielectric Mechanisms and Parameters  

E-Print Network [OSTI]

Electromagnetic Inverse Problems Involving Distributions of Dielectric Mechanisms and Parameters H University, Raleigh, NC 27695-8205 August 17, 2005 Abstract We consider electromagnetic interrogation, uniform, log-normal, and log-Bi-Gaussian distributions. Keywords: Electromagnetic interrogation

39

E-Print Network 3.0 - actinobacillus pleuropneumoniae involved...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

p. 46934694 Vol. 191, No. 14 0021-91930908.00 0 doi:10.1128JB.00447-09 Summary: -tad cluster (AAP0177 to -0190) is similar to the tad locus involved in the rough colony...

40

Unsaturated geotechnics applied to geoenvironmental engineering problems involving geosynthetics  

E-Print Network [OSTI]

such as geotextiles and geosynthetic clay liners (GCLs) with particular focus on capillary barriers, liner performanceUnsaturated geotechnics applied to geoenvironmental engineering problems involving geosynthetics Available online 15 February 2013 Keywords: Capillary break Desiccation Flow Geosynthetics Interface shear

Zornberg, Jorge G.

Note: This page contains sample records for the topic "involvement involvement involvement" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


41

A Self-advocacy Program for Students with Disabilities: Adult Outcomes and Advocacy Involvement One to Six Years after Involvement  

E-Print Network [OSTI]

among advocacy involvement and adult outcomes. To achieve this purpose, former TXYLF participants were surveyed between one and six years after their participation in TXYLF. The correlational study analyzed descriptively the participants outcomes...

Roberts, Eric

2013-03-08T23:59:59.000Z

42

Data augmentation for a Bayesian spatial model involving censored observations  

E-Print Network [OSTI]

Data augmentation for a Bayesian spatial model involving censored observations Brooke L Fridley1 (fax) 1 #12;SUMMARY Spatial environmental data sometimes include below detection limit observations (i. We develop a measurement error Bayesian spatial model for the analysis of spatial data with censored

43

Emerging Trends in Failures Involving EPS-Block Geofoam Fills  

E-Print Network [OSTI]

Emerging Trends in Failures Involving EPS-Block Geofoam Fills John S. Horvath, Ph.D., P.E., M.ASCE1 Abstract: Expanded polystyrene EPS is a closed-cell polymeric "plastic" foam that, in its generic block is due to the fact that block-molded EPS is unique among geofoam products for the large and diverse

Horvath, John S.

44

Evolution, biodiversity, taxonomy Polymorphism of eps loci involved in exopolysaccharide  

E-Print Network [OSTI]

Evolution, biodiversity, taxonomy Polymorphism of eps loci involved in exopolysaccharide synthesis ORFs and five copies of three insertion sequences (IS) types belonging to the eps locus and ORFs sequences from Lactococcus lactis. Further- more, sequence comparison of eps loci of three S

Paris-Sud XI, Université de

45

Incident involving UCSD student(s) takes place. UCSD STUDENT  

E-Print Network [OSTI]

Incident involving UCSD student(s) takes place. UCSD STUDENT CONDUCT PROCESS for individual students (updated 9/20/11) The Office of Student Conduct receives an incident report (i.e. RA, RSO, UCSD Police, student/faculty/staff complaint, etc). If sufficient evidence is present to support a violation

Russell, Lynn

46

LESSONS LEARNED FROM AN IMPOUNDMENT SLOPE FAILURE INVOLVING GEOSYNTHETICS  

E-Print Network [OSTI]

failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment. KEYWORDS: Geosynthetic clay liners, Interface Shear Strength, Waste containment, Strength, Stability to illustrate the importance of (i) properly storing geosynthetic clay liners (GCLs) to reduce the amount

47

Nuclear Decommissioning and Organisational Reliability: Involving Subcontractors in Collective Action  

E-Print Network [OSTI]

Page 1 Nuclear Decommissioning and Organisational Reliability: Involving Subcontractors to the decommissioning. The use of subcontractors is not new; in the nuclear industry it became widespread in the 1990s reliability is at the heart of the safety of at-risk systems. Many studies have been conducted in the nuclear

Paris-Sud XI, Université de

48

Research Article Acetylcholinesterase in intestinal cell differentiation involves  

E-Print Network [OSTI]

involved in the terminal differentiation of enterocytes. Butyrate, a short-chain fatty acid produced in the colonic lumen by microbial fermentation, is taken up by cells of the intestinal epithelium, and serves of acetylcholine to choline and acetate. Interestingly, the expression of AChE is not restricted to cholinergic

Tian, Weidong

49

If the internship is international or involves international travel, the  

E-Print Network [OSTI]

If the internship is international or involves international travel, the student does not need to complete the IRAMS student internship ap- plication, but should contact the Kennedy Center for internship approval and course registration. Flag will be removed, and students will be able to add their internship

Hart, Gus

50

If the internship is international or involves international travel, the  

E-Print Network [OSTI]

If the internship is international or involves international travel, the student does not need to complete the IRAMS student internship application, but should contact the Kennedy Center for internship approval and course registration. Flag will be removed, and students will be able to add their internship

Dahl, David B.

51

DEVELOPMENT AND USE OF A DIRECTORY OF ACCIDENT DATABASES INVOLVING  

E-Print Network [OSTI]

DEVELOPMENT AND USE OF A DIRECTORY OF ACCIDENT DATABASES INVOLVING CHEMICALS J.P.Pineau Institut from end-users of accident data who need validated data for dealing with risk assessment in which Data collection Data analysis, Reliability, Uncertainty, Accident, Hazardous material, Risk analysis

Paris-Sud XI, Université de

52

Modeling of modification experiments involving neutral-gas release  

SciTech Connect (OSTI)

Many experiments involve the injection of neutral gases into the upper atmosphere. Examples are critical velocity experiments, MHD wave generation, ionospheric hole production, plasma striation formation, and ion tracing. Many of these experiments are discussed in other sessions of the Active Experiments Conference. This paper limits its discussion to: (1) the modeling of the neutral gas dynamics after injection, (2) subsequent formation of ionosphere holes, and (3) use of such holes as experimental tools.

Bernhardt, P.A.

1983-01-01T23:59:59.000Z

53

OpenEI:Get Involved | Open Energy Information  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home5b9fcbce19 No revision hasInformation Earth'sOklahoma/Geothermal < Oklahomast,LogisticsOpenEIOpenEIGet Involved Jump to:

54

E-Print Network 3.0 - apoplastic protein involved Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

the WalI Summary: , are now consideredto be fundamentally involved in type 111 protein secretion in phytopathogenic bacteria... proteins may be transient, involve a small...

55

Personnel involved in nuclear standards development: 1980 directory  

SciTech Connect (OSTI)

The development of nuclear standards is an active and necessary endeavor that is concerned with the safe, orderly, and economic development of nuclear potential. There are almost 4100 people from the teachnical community who are presently involved either in writing nuclear standards, including codes, or in the management and processing roles necessary for their approval and promulgation. This document identifies the current participation of each individual as member, chairman, cochairman (vice-chairman), or secretary of about 700 standards development committees and groups. The standards committees and groups are identified with the organizations that are responsible for the preparation, review, and maintenance of the standards and that provide support through supervisory committees and headquarters staff. This directory includes four major sections: personnel, employers, committees, and a Key-Word-in-Context (KWIC) Index of committee titles. It can also be used to identify the participation of employers as well as to recognize the contributions of individuals to the often interdisciplinary activity of standards development.

Carr, S.J. (ed.)

1980-03-01T23:59:59.000Z

56

Representation of analysis results involving aleatory and epistemic uncertainty.  

SciTech Connect (OSTI)

Procedures are described for the representation of results in analyses that involve both aleatory uncertainty and epistemic uncertainty, with aleatory uncertainty deriving from an inherent randomness in the behavior of the system under study and epistemic uncertainty deriving from a lack of knowledge about the appropriate values to use for quantities that are assumed to have fixed but poorly known values in the context of a specific study. Aleatory uncertainty is usually represented with probability and leads to cumulative distribution functions (CDFs) or complementary cumulative distribution functions (CCDFs) for analysis results of interest. Several mathematical structures are available for the representation of epistemic uncertainty, including interval analysis, possibility theory, evidence theory and probability theory. In the presence of epistemic uncertainty, there is not a single CDF or CCDF for a given analysis result. Rather, there is a family of CDFs and a corresponding family of CCDFs that derive from epistemic uncertainty and have an uncertainty structure that derives from the particular uncertainty structure (i.e., interval analysis, possibility theory, evidence theory, probability theory) used to represent epistemic uncertainty. Graphical formats for the representation of epistemic uncertainty in families of CDFs and CCDFs are investigated and presented for the indicated characterizations of epistemic uncertainty.

Johnson, Jay Dean (ProStat, Mesa, AZ); Helton, Jon Craig (Arizona State University, Tempe, AZ); Oberkampf, William Louis; Sallaberry, Cedric J.

2008-08-01T23:59:59.000Z

57

Involvement of Shewanella oneidensis MR-1 LuxS in Biofilm Development...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Involvement of Shewanella oneidensis MR-1 LuxS in Biofilm Development and Sulfur Metabolism. Involvement of Shewanella oneidensis MR-1 LuxS in Biofilm Development and Sulfur...

58

The effects of school gardening on parent involvement in elementary schools  

E-Print Network [OSTI]

to helping with schoolwork at home (Henderson et al. , 1986). Some researchers divide types of involvement according to where it occurs such as in the home?school, or community (NCES, 1997). Others define parent involvement according to how... in parenting, communicating, volunteering, learning at home, decision making, and collaborating with the community (Epstein, 1995). Henderson and others (1986) define parent involvement in terms of the roles that parents have in education such as partners...

Boyer, Roxanne Christina

2002-01-01T23:59:59.000Z

59

E-Print Network 3.0 - alcohol dehydrogenase involved Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

the Summary: resulted in an increased number of reports involving alcohol poisoning, injury, and hospitalization among... Alert: Alcoholic Energy Drinks Carbonated alcoholic...

60

Molecular genetic analysis of activation-tagged transcription factors thought to be involved in photomorphogenesis  

SciTech Connect (OSTI)

This is a final report for Department of Energy Grant No. DE-FG02-08ER15927 entitled Molecular Genetic Analysis of Activation-Tagged Transcription Factors Thought to be Involved in Photomorphogenesis. Based on our preliminary photobiological and genetic analysis of the sob1-D mutant, we hypothesized that OBP3 is a transcription factor involved in both phytochrome and cryptochrome-mediated signal transduction. In addition, we hypothesized that OBP3 is involved in auxin signaling and root development. Based on our preliminary photobiological and genetic analysis of the sob2-D mutant, we also hypothesized that a related gene, LEP, is involved in hormone signaling and seedling development.

Neff, Michael M.

2011-06-23T23:59:59.000Z

Note: This page contains sample records for the topic "involvement involvement involvement" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


61

E-Print Network 3.0 - accumulation involving oxidative Sample...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

of the polymer provides a constant source... of the various formulations on the rate of degradation of EPDM against chain oxidation involved in thermal and UV... the instability...

62

E-Print Network 3.0 - aerogels involving carbon Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Search Powered by Explorit Topic List Advanced Search Sample search results for: aerogels involving carbon Page: << < 1 2 3 4 5 > >> 1 1715 The Meteoritical Society, 2006....

63

E-Print Network 3.0 - analysis results involving Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

3 Department of Mathematics University of Houston Summary: domain. The a posteriori error analysis involves a residual type error estimator consisting of element... analysis...

64

E-Print Network 3.0 - activation involves increasing Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

an initial fixation point. Neural activity was recorded in the superior... colliculus (SC), a structure that is known to be involved in the generation of fast ... Source: Munoz,...

65

E-Print Network 3.0 - aopex11-1 gene involved Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

genes involved in Embden... networks 4. essential genes 5. host-phage co-evolution robust phenomena new mathematical measures... . Clyde Hutchison, 1999 (Science 286, 2165-2169):...

66

antagonist labedipinedilol-a involves: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

67

analysis involving tvs-m: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

68

acetobutylicum involving non-coding: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

69

E-Print Network 3.0 - arene di-oxygenases involved Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

involved Page: << < 1 2 3 4 5 > >> 1 University of Missouri-Columbia Department of Chemistry Summary: Glaser Arene-Arene Interactions Organic Chemistry Seminar on February 27,...

70

Citizen Involvement and Law Enforcement: Does Coproduction Affect Organizational Efficiency and Organizational Effectiveness?.  

E-Print Network [OSTI]

??Citizen involvement in the production and delivery of public service has been a long time topic of interest and controversial debate among scholars. Essentially, the (more)

Gultekin, Sebahattin

2009-01-01T23:59:59.000Z

71

Getting Involved  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsruc DocumentationP-SeriesFlickr Flickr Editor'sshortGeothermal Heat PumpsChad

72

Customer Involvement  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation Proposed Newcatalyst phases onOrganization FY 2012 FYCustomer-Comments Sign In About |default

73

ORIGINAL PAPER On the Role of the Difference in Surface Tensions Involved  

E-Print Network [OSTI]

ORIGINAL PAPER On the Role of the Difference in Surface Tensions Involved in the Allosteric was to develop the relationship between membrane surface tension, and the allosteric balance in a difference in surface tensions that is involved in the creation of a reservoir of intracellular vesicles

Paris-Sud XI, Université de

74

Unravelling aspects of the gas phase chemistry involved in diamond chemical vapour deposition  

E-Print Network [OSTI]

of thin lms of polycrystalline diamond by chemi- cal vapour deposition (CVD) methods,2h4 since which timeUnravelling aspects of the gas phase chemistry involved in diamond chemical vapour deposition been used to unravel details of the gas phase chemistry involved in diamond chemical vapour deposition

Bristol, University of

75

Involving Geospatial Information in the Analysis of Land-Cover Change along the Tanzania Coast  

E-Print Network [OSTI]

Involving Geospatial Information in the Analysis of Land-Cover Change along the Tanzania Coast.1080/08920750590883132 Involving Geospatial Information in the Analysis of Land-Cover Change along the Tanzania Coast YEQIAO WANG and the area of woodland interspersed with agriculture increased. This study demonstrates how geospatial

Wang, Y.Q. "Yeqiao"

76

What is the effect of 4-H involvement on levels of empathy, self-esteem, community involvement and positive view of the future on urban youth?  

E-Print Network [OSTI]

The purpose of the study is to examine the variable of empathy, self-esteem, community involvement, and positive view of the future for both 4-H and non-4-H members in an urban setting. The study also evaluates the link of leadership to empathy...

Bonnett, Erika Dawn

2007-04-25T23:59:59.000Z

77

Ranacyclins, a New Family of Short Cyclic Antimicrobial Peptides: Biological Function, Mode of Action, and Parameters Involved in Target Specificity,,@  

E-Print Network [OSTI]

of Action, and Parameters Involved in Target Specificity,,@ M. Luisa Mangoni, Niv Papo, Giuseppina Mignogna

Pompeu Fabra, Universitat

78

E-Print Network 3.0 - autoantigens pathogenic involvement Sample...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

a regulatory effect of B cells in autoimmune diseases was first provided by Summary: of CIA involved provision of IL10 by collagenspecific B cells4 . The autoantigen activating...

79

An analysis of the protein interactions involved in classical nuclear import  

E-Print Network [OSTI]

Every aspect of eukaryotic cellular life involves the trafficking of proteins and other biomolecules through the nuclear membrane for the purposes of bringing feedback to or information from the nucleus. Many proteins larger than 40 kDa must...

Reedy, Brian Michael Thomas

1999-01-01T23:59:59.000Z

80

Using Visualization Techniques and Gamification to Involve Users in Requirements Elicitation  

E-Print Network [OSTI]

Using Visualization Techniques and Gamification to Involve Users in Requirements Elicitation Diogo of visualization techniques and gamification. Requirements visualizations are used to stimulate stakeholders and increase their awareness about requirements. Social visualization and gamification of the elicitation

da Silva, Alberto Rodrigues

Note: This page contains sample records for the topic "involvement involvement involvement" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


81

A study of parental involvement and school climate: Perspective from the middle school  

E-Print Network [OSTI]

This study examines school level differences on different dimensions of teacherrated parent involvement and school climate while adjusting for age, gender, ethnicity, how certified, and number of years teaching. Two hundred twenty-four elementary...

Dixon, Shantina Rayford

2009-05-15T23:59:59.000Z

82

School-Based Family Involvement: Patterns and Predictors in the NLTS2  

E-Print Network [OSTI]

This investigation used data from the National Longitudinal Transition Study 2 (NLTS2) to investigate patterns among student, family, and school characteristics, school outreach programs, and school-based family involvement for families of 5...

Frew, Leigh Ann

2012-10-19T23:59:59.000Z

83

E-Print Network 3.0 - accidents involving fuel Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Education for the newspaper NRC- Summary: , since it tells you how many kilomters an automobile has to travel before it is involved in an accident... one kilometer by automobile...

84

E-Print Network 3.0 - akt signaling involved Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

results for: akt signaling involved Page: << < 1 2 3 4 5 > >> 1 Tumor and Stem Cell Biology Akt2 Regulates All Akt Isoforms and Promotes Resistance to Summary: that hypoxia...

85

E-Print Network 3.0 - aspergillus enzymes involved Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

an Aspergillus fumigatus question Until the 1980s, it seemed to be clear that the main fungus Summary: , it seemed to be clear that the main fungus involved in aspergillosis in...

86

Staying Competitive in the 90's: How to Make Public Involvement Work for Your Energy Project  

E-Print Network [OSTI]

Gone are the days when energy companies could develop energy, void of citizen input. With the passage of the National Environmental Policy Act in 1969, a new era of public involvement began. Although the specifics of how the public should...

Loveless, K. W.

87

E-Print Network 3.0 - alter genes involved Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

5 MAY 2006 537 Gene prioritization through genomic Summary: Carmeliet2 & Yves Moreau4 The identification of genes involved in health and disease remains a challenge. We... on their...

88

Nucleotide diversity and neutrality testing in genes involved in adaptation in Douglas-fir  

E-Print Network [OSTI]

Nucleotide diversity and neutrality testing in genes involved in adaptation in Douglas-fir B. Pande-Oregon region, and 684 SNPs were identified in total. We report the estimation of nucleotide diversity and tests

89

Examination of offsite radiological emergency protective measures for nuclear reactor accidents involving core melt  

E-Print Network [OSTI]

Evacuation, sheltering followed by population relocation, and iodine prophylaxis are evaluated as offsite public protective measures in response to nuclear reactor accidents involving core-melt. Evaluations were conducted ...

Aldrich, David C.

1979-01-01T23:59:59.000Z

90

Molecular architecture of DesV from Streptomyces venezuelae: A PLP-dependent transaminase involved in  

E-Print Network [OSTI]

Molecular architecture of DesV from Streptomyces venezuelae: A PLP-dependent transaminase involved are required for its biosynthesis in Streptomyces venezuelae. The focus of this article is DesV, which

Holden, Hazel

91

Money Smart Evaluation Process Evaluation of the Money Smart program involves 3 parts  

E-Print Network [OSTI]

Money Smart Evaluation Process Evaluation of the Money Smart program involves 3 parts: o Pre on the FCS Agent website under Money Smart. End of session evaluations are also included in the Instructor

92

"The operation and development of air-ports generally involves the lease of dedicat-  

E-Print Network [OSTI]

Leases "The operation and development of air- ports generally involves the lease of dedicat- ed property. · The right to approve or deny any lease or sublease of the premises, on the air- port or owned

Minnesota, University of

93

Inter-kingdom Recognition of Norepinephrine by E. Coli : Identification of the Receptors Involved in Chemotaxis  

E-Print Network [OSTI]

INTER- KINGDOM RECOGNITION OF NOREPINEPHRINE BY E. COLI: IDENTIFICATION OF THE RECEPTORS INVOLVED IN CHEMOTAXIS A Thesis by DAE NYUN KIM Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment... of the requirements for the degree of MASTER OF SCIENCE August 2012 Major Subject: Chemical Engineering INTER- KINGDOM RECOGNITION OF NOREPINEPHRINE BY E. COLI: IDENTIFICATION OF THE RECEPTORS INVOLVED IN CHEMOTAXIS A Thesis by DAE NYUN KIM...

Kim, Dae Nyun

2012-10-19T23:59:59.000Z

94

Proposed Tenaska Washington II Generation Project : Final Environmental Impact Statement. Volume 2: Public Involvement.  

SciTech Connect (OSTI)

In regard to the proposed Tenaska Washington II Generation Project, the goal of the Bonneville Power Administration`s (BPA) Environmental Impact Statement (EIS) public involvement process is to determine the issues to be examined and pertinent analyses to be conducted and to solicit comments on the content and quality of information presented in the Draft Environmental Impact Statement (DEIS). Comments and questions are solicited from the public and government agencies during the scoping process and during the comment period and public hearing on the DEIS, to find out what is of most concern to them. The end product of the public involvement process is the Comment Report which follows in part of this volume on Public Involvement.

United States. Bonneville Power Administration.

1994-01-01T23:59:59.000Z

95

A study to examine community involvement in major U.S.military base closures and realignments from 1988 to 2001  

E-Print Network [OSTI]

This study examines community involvement in major U.S. military base closures and realignments from 1988 to 2001. There were four waves of base closures during this time. They were in 1988, 1991, 1993, and 1995. Community involvement became...

Yahn, Nancy Stiles

2005-11-01T23:59:59.000Z

96

arXiv:hep-ex/0211027v111Nov2002 Search for neutrinoless decays involving the K0  

E-Print Network [OSTI]

arXiv:hep-ex/0211027v111Nov2002 1 Search for neutrinoless decays involving the K0 S meson K neutrinoless LFV modes within a model involving heavy Dirac neutrinos. The branching fractions depend

97

Study Finds that Children with Autism and Gastrointestinal Symptoms Have Altered Expression of Genes Involved in Digestion  

E-Print Network [OSTI]

of Genes Involved in Digestion These changes may also affect the mix of bacteria present in the digestive disturbances have altered expression of genes involved in digestion. These variations may contribute to changes

Salzman, Daniel

98

Ohio State Colleges/Units Involved College of Arts and Sciences  

E-Print Network [OSTI]

Affairs Community Partners Involved Indian Universities: Aligarh Muslim University Delhi University Saudi Arabian universities Obama-Singh 21st Century Knowledge Initiative Award Project: STEM Education members. For the project, the OSU partnership with Aligarh Muslim University (AMU) in India received one

Nahar, Sultana Nurun

99

Shutdown mechanisms for a hypothetical criticality accident involving HEU powder: Preliminary results  

SciTech Connect (OSTI)

This work examines the physical processes that would cause an accidental criticality involving higly enriched uranium(HEU) powder to shut down naturally. The study analyses an excursion resulting from the continous poring of slightly damp HEU powder (either UO{sub 3} or UF{sub 4} containing 1.5% water) onto a concrete floor.

Bentley, C.; Basoglu, B.; Dunn, M.; Plaster, M.; Ruggles, A.; Wilkinson, A.; Yamamoto, T.; Dodds, H. [Univ. of Tennessee, Knoxville, TN (United States)

1994-12-31T23:59:59.000Z

100

Hf isotope compositions of northern Luzon arc lavas suggest involvement of pelagic sediments in their source  

E-Print Network [OSTI]

1 Hf isotope compositions of northern Luzon arc lavas suggest involvement of pelagic sediments passing through the data intersect fields for depleted mantle and pelagic sediments suggesting. The relationship between Nd and Hf isotopic compositions in the Luzon volcanics show that the type of sediment

Boyer, Edmond

Note: This page contains sample records for the topic "involvement involvement involvement" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


101

FRIGIDA Delays Flowering in Arabidopsis via a Cotranscriptional Mechanism Involving Direct  

E-Print Network [OSTI]

a novel nuclear protein with no conserved domains except for two coiled-coil regions. A mutation in spring. In Arabidopsis (Arabidopsis thaliana), a major determinant of this life history strategy flowering in spring. Vernalization has been shown to involve changes in histone modi- fications at FLC

Howard, Martin

102

PCA-based bootstrap confidence interval tests for gene-disease association involving multiple SNPs  

E-Print Network [OSTI]

2005, 77:567-581. 23. Kallberg H, Padyukov L, Plenge RM, Ronnelid J, Gregersen PK, Helm-van Mil van der AHM, Toes REM, Huizinga TW, Klareskog L, Alfredsson L, et al: Gene-gene and gene-environment interactions involving HLA-DRB1, PTPN22, and smoking...

Peng, Qianqian; Zhao, Jinghua; Xue, Fuzhong

2010-01-26T23:59:59.000Z

103

On the Cover: One route to harvesting the energy of the sun involves learning to mimic  

E-Print Network [OSTI]

plants. This many plants would need to be constructed to meet global demands for carbon-neutral energy#12;On the Cover: One route to harvesting the energy of the sun involves learning to mimic natural the chlorophylls, which play a central role in capturing light and using its energy for photosynthesis in green

Wu, Zhigang

104

Parabolic equation solution of seismo-acoustics problems involving variations in bathymetry and sediment thickness  

E-Print Network [OSTI]

and sediment thickness Jon M. Collisa and William L. Siegmann Rensselaer Polytechnic Institute110 8th Street within elastic sediment layers. When these methods are implemented together, the parabolic equation method can be applied to problems involving variations in bathymetry and the thickness of sediment layers

105

Safety First Safety Last Safety Always Roughly one out of every four accidents (25%) involves  

E-Print Network [OSTI]

Safety First Safety Last Safety Always Roughly one out of every four accidents (25%) involves at an unsafe speed · Failure to check mirrors often Fleet Safety: Backing Accidents Safety Tip #2 Accidents hurt-- safety doesn't. All backing accidents are preventable. The key is to plan ahead to avoid backing

Minnesota, University of

106

Differing Professional Opinions Manual for Technical Issues Involving Environment, Safety, and Health  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

This Manual establishes a differing professional opinion (DPO) policy to a Department of Energy (DOE) Differing Professional Opinion (DPO) Process to encourage and facilitate dialogue and resolution on DPOs from employees for technical issues involving environment, safety, and health. Does not cancel other directives. Canceled by DOE O 442.2.

2006-11-16T23:59:59.000Z

107

Molecular and Genetic Evidence for a Virus-Encoded Glycosyltransferase Involved in Protein Glycosylation1  

E-Print Network [OSTI]

capsid protein, Vp54, of chlorella virus PBCV-1 is a glycoprotein that contains either one glycan of 30-encoded glycosyltransferase involved in protein glycosylation. © 2001 Academic Press Key Words: chlorella virus; PBCV-1; Phycodnaviridae; virus glycoprotein; glycosyltransferase. INTRODUCTION Paramecium bursaria chlorella virus-1 (PBCV

Graves, Michael V.

108

DEA Efficiency Analysis Involving Multiple Production Processes with an Application to  

E-Print Network [OSTI]

with which input resources are allocated to the subunits. It introduces a simple model for efficientlyDEA Efficiency Analysis Involving Multiple Production Processes with an Application to Urban Mass in the Department of Information Systems and Technology within in the College of Business Administration

Illinois at Chicago, University of

109

Emergency Action Plan For incidents involving hazardous materials, fires, explosions, or natural gas  

E-Print Network [OSTI]

-492-6025. For Non-Emergency Fire and Natural Gas Questions call the CU Fire Marshall @ 303-492-4042. AdditionalEmergency Action Plan For incidents involving hazardous materials, fires, explosions, or natural gas leaks, the following actions should be taken: 1) Life Safety First 2) Evacuate Immediate Area 3

Mojzsis, Stephen J.

110

Involvement of the Czech environmental movements in the European game: which impact on their repertory of  

E-Print Network [OSTI]

73 Involvement of the Czech environmental movements in the European game: which impact observe that each country is embedded in its own history. Communism for example, has been experienced. In my own case, these issues have been analysed using Czech environmental actors. #12;Social Movement

Paris-Sud XI, Université de

111

PROJECT GOALS This project involved the development of the first Carbon  

E-Print Network [OSTI]

emissions, which will in turn allow prioritisation of actions to reduce the ANU carbon footprint. TYPEPROJECT GOALS This project involved the development of the first Carbon Emissions Inventory report and master Excel spreadsheet Figure 1: ANU Carbon Emission by Category (t CO2e) DESCRIPTION

112

Mycobacterium tuberculosis Strains Potentially Involved in the TB Epidemic in Sweden a Century Ago  

E-Print Network [OSTI]

Mycobacterium tuberculosis Strains Potentially Involved in the TB Epidemic in Sweden a Century Ago, Swedish Institute for Communicable Disease Control, Solna, Sweden, 2 Tuberculosis and Mycobacteria Unit Department of Clinical Science and Education, Karolinska Institutet, So¨dersjukhuset, Stockholm, Sweden

Paris-Sud XI, Université de

113

Cytosolic High Km 5 -Nucleotidase and 5 (3 )-Deoxyribonucleotidase in Substrate Cycles Involved in Nucleotide Metabolism*  

E-Print Network [OSTI]

in Nucleotide Metabolism* Received for publication, August 21, 2000, and in revised form, November 14, 2000 that the hkm-NT is not involved in the regulation of deoxyribo- nucleotide pools but affects IMP and GTP pools. dNT-1, instead, appears to be the catabolic arm of substrate cycles regulating pyrimidine nucleotide

Bianchi, Vera

114

Magnesium Ion-dependent Activation of the RecA Protein Involves the C Terminus*  

E-Print Network [OSTI]

Magnesium Ion-dependent Activation of the RecA Protein Involves the C Terminus* Received with ATP. We provide evi- dence that the free magnesium ion is required to medi- ate a conformational at low magnesium ion concentrations. The RecA protein of Escherichia coli plays a central role

Cox, Michael M.

115

Incident Report An incident report should be submitted for any event involving  

E-Print Network [OSTI]

Incident Report An incident report should be submitted for any event involving: injury or illness fire explosion or implosion chemical exposure Minor cuts and scrapes need not be reported be reported. If a "near miss" might have had severe consequences, submit an incident report. You may also

Crawford, T. Daniel

116

RASRAFMEK-dependent oxidative cell death involving voltage-dependent anion channels  

E-Print Network [OSTI]

LETTERS RASRAFMEK-dependent oxidative cell death involving voltage-dependent anion channels J. Fridman1 , Adam J. Wolpaw1 , Inese Smukste1 , John M. Peltier3 , J. Jay Boniface3 , Richard Smith that discriminate between the genetic makeup of normal cells and tumour cells are valuable for treating and under

Stockwell, Brent R.

117

Weather encapsulates the state of the atmosphere, primarily involving the component which affects  

E-Print Network [OSTI]

1 #12;2 Weather encapsulates the state of the atmosphere, primarily involving the component which and Telegraph readers tend to use oF #12;5 The human body has an energy balance just like the Earth (solar range in larger on still, clear days, when solar heating is strong at the surface and is not offset

Allan, Richard P.

118

Involvement of extracellular calcium inux in the self-incompatibility response of Papaver rhoeas  

E-Print Network [OSTI]

Involvement of extracellular calcium in¯ux in the self- incompatibility response of Papaver rhoeas in cytosolic free Ca2+ are triggered by the self- incompatibility (SI) response in incompatible Papaver rhoeas with self-incompatibility (S) proteins, there is a stimulation of Ca2+ in¯ux along the shank of incompatible

Kunkel, Joseph G.

119

A comparative genomic analysis of the oxidative enzymes potentially involved in lignin degradation by Agaricus bisporus  

E-Print Network [OSTI]

A comparative genomic analysis of the oxidative enzymes potentially involved in lignin degradation an important role in lignin degradation. On the other hand, the expression patterns of the related CROs suggest of the global carbon cycle. This substrate is composed of lignin, hemicellulose and cellulose and is degraded

Fried, Jeremy S.

120

A Tomato Peroxidase Involved in the Synthesis of Lignin and Suberin1  

E-Print Network [OSTI]

A Tomato Peroxidase Involved in the Synthesis of Lignin and Suberin1 Mo´nica Quiroga, Consuelo´laga, Spain (A.B.) The last step in the synthesis of lignin and suberin has been proposed to be catalyzed in the synthesis of lignin and suberin, five peroxidases from tomato (Lycopersicon esculentum) roots, representing

Málaga, Universidad de

Note: This page contains sample records for the topic "involvement involvement involvement" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


121

Thermal Sciences The thermal sciences area involves the study of energy conversion and transmission, power  

E-Print Network [OSTI]

Thermal Sciences The thermal sciences area involves the study of energy conversion and transmission, power generation, the flow of liquids and gases, and the transfer of thermal energy (heat) by means in virtually all energy conversion devices and systems. One may think of the jet engine as a mechanical device

New Hampshire, University of

122

Second-order integrals of motion for spin involving systems in $E_2$  

E-Print Network [OSTI]

In two-dimensional Euclidean plane, existence of second-order integrals of motion is investigated for integrable Hamiltonian systems involving spin (\\emph{e.g.,} those systems describing interaction between two particles with spin 0 and spin 1/2) and it has been shown that no nontrivial second-order integrals of motion exist for such systems.

Ismet Yurdusen

2014-07-16T23:59:59.000Z

123

Final report on the public involvement process phase 1, Monitored Retrievable Storage Facility Feasibility Study  

SciTech Connect (OSTI)

This report summarizes the pubic involvement component of Phase 1 of the Monitored Retrievable Storage Facility (NM) Feasibility Study in San Juan County, Utah. Part of this summary includes background information on the federal effort to locate a voluntary site for temporary storage of nuclear waste, how San Juan County came to be involved, and a profile of the county. The heart of the report, however, summarizes the activities within the public involvement process, and the issues raised in those various forums. The authors have made every effort to reflect accurately and thoroughly all the concerns and suggestions expressed to us during the five month process. We hope that this report itself is a successful model of partnership with the citizens of the county -- the same kind of partnership the county is seeking to develop with its constituents. Finally, this report offers some suggestions to both county officials and residents alike. These suggestions concern how decision-making about the county's future can be done by a partnership of informed citizens and listening decision-makers. In the Appendix are materials relating to the public involvement process in San Juan County.

Moore, L.; Shanteau, C.

1992-12-01T23:59:59.000Z

124

Final report on the public involvement process phase 1, Monitored Retrievable Storage Facility Feasibility Study  

SciTech Connect (OSTI)

This report summarizes the pubic involvement component of Phase 1 of the Monitored Retrievable Storage Facility (NM) Feasibility Study in San Juan County, Utah. Part of this summary includes background information on the federal effort to locate a voluntary site for temporary storage of nuclear waste, how San Juan County came to be involved, and a profile of the county. The heart of the report, however, summarizes the activities within the public involvement process, and the issues raised in those various forums. The authors have made every effort to reflect accurately and thoroughly all the concerns and suggestions expressed to us during the five month process. We hope that this report itself is a successful model of partnership with the citizens of the county -- the same kind of partnership the county is seeking to develop with its constituents. Finally, this report offers some suggestions to both county officials and residents alike. These suggestions concern how decision-making about the county`s future can be done by a partnership of informed citizens and listening decision-makers. In the Appendix are materials relating to the public involvement process in San Juan County.

Moore, L.; Shanteau, C.

1992-12-01T23:59:59.000Z

125

Predicting Pelvic Lymph Node Involvement in Current-Era Prostate Cancer  

SciTech Connect (OSTI)

Purpose: The Roach formula [2/3 Multiplication-Sign prostate-specific antigen + (Gleason score - 6) Multiplication-Sign 10], derived in 1993 during the early prostate specific antigen (PSA) screening era, has been used to predict the risk of pelvic lymph node involvement in patients with prostate cancer. In the current era of widespread PSA screening with a shift to earlier disease stages, there is evidence to suggest that the Roach score overestimates risk of nodal metastasis. This study retrospectively reviews the validity of this formula as a prediction tool. Methods and Materials: We conducted a retrospective institutional review including men with clinical T1c-T3 prostate cancer, with baseline PSA levels and biopsy-obtained Gleason scores who underwent radical prostatectomy with pelvic node dissection from 2001 through 2009 (N = 1,022). The predicted risk of nodal involvement was calculated for each patient using the Roach formula and then compared with actual rates following surgery. Results: The study included 1,022 patients; 99.6% had clinical T1c/T2 disease, with a mean of 10.3 lymph nodes surgically evaluated. Overall, 42 patients (4.1%) had nodal metastasis. For every range of scores, the Roach formula overestimates the risk of nodal involvement. Observed nodal positivity was 1%, 6.3%, 10%, 15.2%, and 16.7% for Roach scores {<=}10%, >10%-20%, >20%-30%, >30%-40%, and >40%, respectively. The Roach score overestimates the risk by approximately 4.5-fold in patients with scores {<=}10%, by 2.5-fold for all scores between 10% and 40%, and by 4-fold for scores >40%. Conclusion: The Roach formula overpredicts the risk of pelvic nodal involvement in current-era prostate cancer patients undergoing regular PSA screening and with mainly T1c/T2 disease. Contemporary patients are much less likely to have nodal involvement for a given PSA and Gleason score.

Rahman, Sophia, E-mail: sophs1578@yahoo.com [Kaiser Permanente Medical Center, Department of Radiation Oncology, Los Angeles, CA (United States); Cosmatos, Harry [Kaiser Permanente Medical Center, Department of Radiation Oncology, Los Angeles, CA (United States); Dave, Giatri [Kaiser Permanente Medical Center, Department of Radiation Oncology, Fresno, CA (United States); Williams, Stephen [Kaiser Permanente Medical Center, Department of Urology, Los Angeles, CA (United States); Tome, Michael [Kaiser Permanente Medical Center, Department of Radiation Oncology, Los Angeles, CA (United States)

2012-02-01T23:59:59.000Z

126

Developing prototype indicators of value and costs added through public involvement programs  

SciTech Connect (OSTI)

As more managers realize that public input in public sector decision making is a given in the current political and social climate, many are turning to public involvement (PI) as a way to manage the input so that it is beneficial to their decisions and projects. Public involvement is starting to become a familiar way of doing business for the Department of Energy (DOE) and its contractors. DOE and contractors are still unclear about the value and costs that PI can provide to their projects. Proponents claim that PI increases the acceptability of project goals by increasing stakeholders knowledge about and involvement in decisions of importance to them. In spite of these assertions avowing the benefits of PI, proponents have not generated methods that demonstrate or provide evidence of the value added through incorporating PI into projects. As DOE and contract managers are increasingly directed to incorporate public input in their project planning and decision making, questions are beginning to surface about the value and costs of PI as a way to manage that input. There is a pressing need to document the value and costs of PI for the participants in these processes--the stakeholders--and to present this information to decision makers in a way that helps them assess the value and costs of managing public input through a PI program. This research project focuses on developing a series of indicators to assess the value and costs of using public involvement programs to manage public input in decision making processes. The dimensions of public involvement that participants perceive as adding value or costs to projects; and developing ways to measure those dimensions through social indicators and metrics of behavior are outlined.

Lach, D.; Hixson, P.; Silbernagel, M.; Branch, K.; Heerwagen, J.; Bradbury, J.

1995-01-01T23:59:59.000Z

127

Public involvement in integrated resource planning: A study of demand-side management collaboratives  

SciTech Connect (OSTI)

Many utilities and nonutility parties (NUPs) across the country have tried a new approach to reaching agreement on Demand-Side Management (DSM) program design and policy issues. Through this, which is called the DSM collaborative process, parties who have often been adversaries in the past attempt to reach consensus rather than using traditional litigation to resolve differences. We examined nine cases of DSM collaboration involving 24 utilities and approximately 50 NUPs in 10 states. This is the first comprehensive, in-depth review and assessment of collaboratives and it allows conclusions to be drawn about the collaborative process and the factors that contribute to successful efforts of this type. Collaboratives are described in terms of four major contextual and organizational characteristics: regulatory and legal history, parties involved and parties excluded, collaborative scope, and the collaborative process itself.

Raab, J. [Raab (J.), Boston, MA (United States); Schweitzer, M. [Oak Ridge National Lab., TN (United States)

1992-02-01T23:59:59.000Z

128

The interactive effects of individual learning style, computer software, and teacher involvement on developing typing skill  

E-Print Network [OSTI]

THE INTERACTIVE EFFECTS OF INDIVIDUAL LEARNING STYLE, COMPUTER SOFTWARE, AND TEACHER INVOLVEMENT ON DEVELOPING TYPING SKILL A Thesis by SARINA RENAE GOODMAN Submitted to the Office of Graduate Studies of Texas Ag:M University in partial... by SARINA RENAE GOODMAN Submitted to the Office of Graduate Studies of Texas AkM University in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE Approved as to style and content by: Newton Ellis (Chair of Committee) Rodger...

Goodman, Sarina Renae

1995-01-01T23:59:59.000Z

129

Combining information processing, personality, and demographic variables to predict motor vehicle crash involvement  

E-Print Network [OSTI]

and reflects attitudes, beliefs, and motivations of drivers (Elander et al. , 1993). McGwire (1976) has suggested that, in general, people who are involved in accidents are emotionally immature, irresponsible, unhappy, and more likely to have a disturbed... crashes, although this approach is often successfully used in other areas. For instance, Hansen (1989) proposed a viable model of the cause of industrial accidents that included biodata, personality, and cognitive factors. As suggested by Lawton...

Hanson, Amber Ann

2000-01-01T23:59:59.000Z

130

Effects of Parent Expectations and Involvement on the School Readiness of Children in Head Start  

E-Print Network [OSTI]

EFFECTS OF PARENT EXPECTATIONS AND INVOLVEMENT ON THE SCHOOL READINESS OF CHILDREN IN HEAD START A Dissertation by KRYSTAL TISHA? COOK Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment... of children enrolled in Head Start. The study examined how these iv parent variables were related to children?s school readiness, and differences between ethnic groups, gender groups, and level of risk. The study tested a model whereby the effect...

Cook, Krystal Tisha'

2010-10-12T23:59:59.000Z

131

A review of two recent occurrences at the Advanced Test Reactor involving subcontractor activities  

SciTech Connect (OSTI)

This report documents the results of a brief, unofficial investigation into two incidents at the Idaho National Engineering and Environmental Laboratory (INEEL) Advanced Test Reactor (ATR) facility, reported on October 25 and 31, 1997. The first event was an unanticipated breach of confinement. The second involved reactor operation with an inoperable seismic scram subsystem, violating the reactor`s Technical Specifications. These two incidents have been found to be unrelated. A third event that occurred on December 16, 1996, is also discussed because of its similarities to the first event listed above. Both of these incidents were unanticipated breaches of confinement, and both involved the work of construction subcontractor personnel. The cause for the subcontractor related occurrences is a work control process that fails to effectively interface with LMITCO management. ATR Construction Project managers work sufficient close with construction subcontractor personnel to understand planned day-to-day activities. They also have sufficient training and understanding of reactor operations to ensure adherence to applicable administrative requirements. However, they may not be sufficiently involved in the work authorization and control process to bridge an apparent communications gap between subcontractor employees and Facility Operations/functional support personnel for work inside the reactor facility. The cause for the inoperable seismic scram switch (resulting from a disconnected lead) is still under investigation. It does not appear to be subcontractor related.

Dahlke, H.J.; Jensen, N.C.; Vail, J.A.

1997-11-01T23:59:59.000Z

132

The Function and Genetic Interactions of Zebrafish atoh1 and sox2: Genes Involved in Hair Cell Development and Regeneration  

E-Print Network [OSTI]

THE FUNCTION AND GENETIC INTERACTIONS OF ZEBRAFISH atoh1 AND sox2: GENES INVOLVED IN HAIR CEL DEVELOPMENT AND REGENERATION A Disertation by BONY BUTLER MILIMAKI Submited to the Ofice of Graduate Studies of Texas A... Involved in Hair Cel Development and Regeneration. Copyright 2010 Bonny Butler Milimaki THE FUNCTION AND GENETIC INTERACTIONS OF ZEBRAFISH atoh1 AND sox2: GENES INVOLVED IN HAIR CEL DEVELOPMENT AND REGENERATION A Disertation by BONY...

Millimaki, Bonny Butler

2010-10-12T23:59:59.000Z

133

THE RELATIONSHIP BETWEEN HIGH INVOLVEMENT WORK SYSTEMS, SUPERVISORY SUPPORT, AND ORGANIZATIONAL EFFECTIVENESS: THE ROLE OF EMPLOYEE EXPERIENCES AT WORK  

E-Print Network [OSTI]

This study adopts a multilevel, multiple stakeholder perspective to examine the impact of high involvement work systems (HIWS) and supervisory support on organizational effectiveness. Organizational effectiveness is measured ...

Wadhwa, Preeti

2012-08-31T23:59:59.000Z

134

Involvement of purinergic system in inflammation and toxicity induced by copper in zebrafish larvae  

SciTech Connect (OSTI)

The use of zebrafish (Danio rerio) is increasing as an intermediate preclinical model, to prioritize drug candidates for mammalian testing. As the immune system of the zebrafish is quite similar to that of mammals, models of inflammation are being developed for the screening of new drugs. The characterization of these models is crucial for studies that seek for mechanisms of action and specific pharmacological targets. It is well known that copper is a metal that induces damage and cell migration to hair cells of lateral line of zebrafish. Extracellular nucleotides/nucleosides, as ATP and adenosine (ADO), act as endogenous signaling molecules during tissue damage by exerting effects on inflammatory and immune responses. The present study aimed to characterize the inflammatory status, and to investigate the involvement of the purinergic system in copper-induced inflammation in zebrafish larvae. Fishes of 7 days post-fertilization were exposed to 10 ?M of copper for a period of 24 h. The grade of oxidative stress, inflammatory status, copper uptake, the activity and the gene expression of the enzymes responsible for controlling the levels of nucleotides and adenosine were evaluated. Due to the copper accumulation in zebrafish larvae tissues, the damage and oxidative stress were exacerbated over time, resulting in an inflammatory process involving IL-1?, TNF-?, COX-2 and PGE{sub 2}. Within the purinergic system, the mechanisms that control the ADO levels were the most involved, mainly the reactions performed by the isoenzyme ADA 2. In conclusion, our data shed new lights on the mechanisms related to copper-induced inflammation in zebrafish larvae. - Graphical abstract: This scheme provides a chronological proposition for the biochemical events induced by copper in zebrafish larvae. The dashed line shows the absorption of copper over the exposure time. After 1 h of exposure to copper, the release of PGE{sub 2} occurs, followed by an increase of MPO (as a consequence of neutrophil migration), increased expression of genes involved in inflammatory events (IL-1? and TNF-?) and, reduction of the anti-inflammatory cytokine IL-10 at 4 h. At 24 h, the copper concentration is found highly increased, what is coincident with oxidative stress. Regarding the purinergic system, it is possible to observe an inhibition of ecto-5?-NT and ADA, with the consequent increase of AMP and ADA, respectively, at 24 h. The expression of enzyme-related genes shows a decrease in the expression of ecto-5?-NT and variable expressions of ADA subfamily enzymes. - Highlights: Copper led to increased oxidative stress, and decreased the antioxidants' defenses. Copper induced time-related changes of IL-1?, TNF-?, IL-10 and PGE{sub 2} levels. ADA activity controls the levels of adenosine in copper-induced inflammation. ADA 2 is the main ADA subfamily involved. The purinergic system seems to be involved in the resolution of inflammation.

Leite, Carlos Eduardo, E-mail: carlos.leite@pucrs.br [Instituto de Toxicologia e Farmacologia, Pontifcia Universidade Catlica do Rio Grande do Sul, Porto Alegre, CEP 90619-900 (Brazil); Programa de Ps-Graduao em Medicina: Cincias Mdicas, Universidade Federal do Rio Grande do Sul, Porto Alegre, CEP 90035-003 (Brazil); Maboni, Lucas de Oliveira [Instituto de Toxicologia e Farmacologia, Pontifcia Universidade Catlica do Rio Grande do Sul, Porto Alegre, CEP 90619-900 (Brazil); Faculdade de Biocincias, Pontifcia Universidade Catlica do Rio Grande do Sul, Porto Alegre, CEP 90619-900 (Brazil); Cruz, Fernanda Fernandes [Instituto de Toxicologia e Farmacologia, Pontifcia Universidade Catlica do Rio Grande do Sul, Porto Alegre, CEP 90619-900 (Brazil); Faculdade de Farmcia, Pontifcia Universidade Catlica do Rio Grande do Sul, Porto Alegre, CEP 90619-900 (Brazil); Rosemberg, Denis Broock [Programa de Ps-graduao em Cincias Ambientais, Universidade Comunitria da Regio de Chapec, Chapec, CEP 89809-000 (Brazil); and others

2013-11-01T23:59:59.000Z

135

Identification and Characterization of Soluble Factors Involved in Delayed Effects of Low Dose Radiation. Final report  

SciTech Connect (OSTI)

This is a 'glue grant' that was part of a DOE Low Dose project entitled 'Identification and Characterization of Soluble Factors Involved in Delayed Effects of Low Dose Radiation'. This collaborative program has involved Drs. David L. Springer from Pacific Northwest National Laboratory (PNNL), John H. Miller from Washington State University, Tri-cities (WSU) and William F. Morgan then from the University of Maryland, Baltimore (UMB). In July 2008, Dr. Morgan moved to PNNL and Dr. Janet E. Baulch became PI for this project at University of Maryland. In November of 2008, a one year extension with no new funds was requested to complete the proteomic analyses. The project stemmed from studies in the Morgan laboratory demonstrating that genomically unstable cells secret a soluble factor or factors into the culture medium, that cause cytogenetic aberrations and apoptosis in normal parental GM10115 cells. The purpose of this project was to identify the death inducing effect (DIE) factor or factors, estimate their relative abundance, identify the cell signaling pathways involved and finally recapitulate DIE in normal cells by exogenous manipulation of putative DIE factors in culture medium. As reported in detail in the previous progress report, analysis of culture medium from the parental cell line, and stable and unstable clones demonstrated inconsistent proteomic profiles as relate to candidate DIE factors. While the proposed proteomic analyses did not provide information that would allow DIE factors to be identified, the analyses provided another important set of observations. Proteomic analysis suggested that proteins associated with the cellular response to oxidative stress and mitochondrial function were elevated in the medium from unstable clones in a manner consistent with mitochondrial dysfunction. These findings correlate with previous studies of these clones that demonstrated functional differences between the mitochondria of stable and unstable clones. These mitochondrial abnormalities in the unstable clones contributes to oxidative stress.

Baulch, Janet

2013-09-11T23:59:59.000Z

136

Report on a workshop on transportation-accident scenarios involving spent fuel  

SciTech Connect (OSTI)

Much confusion and skepticism resulted from the scenarios for transportation accidents involving spent fuel that have been presented in environmental impact statements because the supporting assumptions and conclusions from the scenarios did not always appear to be consistent. As a result, the Transportation Technology Center gathered a group whose participants were experts in disciplines related to the transport of spent fuel to consider the scenarios. The group made a number of recommendations about scenario development and about areas in need of further study. This report documents the discussions held and the recommendations and conclusions of the group.

Wilmot, E.L.; McClure, J.D.; Luna, R.E.

1981-02-01T23:59:59.000Z

137

MATH5215, Some Questions Involving ep(t, t0) May 22, 2005  

E-Print Network [OSTI]

MATH5215, Some Questions Involving ep(t, t0) May 22, 2005 1. Consider the following dynamic IVP on arbitrary T y = p(t)y, p R,(0.1) y(t0) = 1, t0 T.(0.2) Show that the only solution to (0.1), (0.2) is ep(t, t0). (Hint: Let y be a solution to the IVP and show y(t) ep(t, t0) = 0 so that y(t) ep(t,t0

Tisdell, Chris

138

A test of the continuous spontaneous localization model involving two particles  

E-Print Network [OSTI]

We describe a previously unexplored effect of the continuous spontaneous localization model whereby a correlation develops in the distributions of two nearby non-interacting particles following a period of diffusion. We propose the use of this effect as an experimental test differentiating between the continuous spontaneous localization model and standard quantum theory. The test involves building a joint probability distribution for the locations of the two particles by repeatedly releasing them from two nearby traps and subsequently measuring their positions after a brief period of time. We examine the scales of time, trap size, and particle mass necessary for observation.

Daniel Bedingham

2014-11-26T23:59:59.000Z

139

The Conducting of a Mining Negotiation Showing the Scheme of Engineering Involved  

E-Print Network [OSTI]

and capable of lifting the heaviest piece of any one of these machines. CEAIIT BLOCKS:- One fl) 8 ton triplex chain block, complete, equip- ped with sufficient chain for a 14* lift. One (1) 3 ton triplex chain block, equipped with sufficient chain for a 22... E S I S , "The conducting of a Mining negotiation Show- ng the Scheme of Engineering Involved." Taken from Actual Practice 13 7 SEQRGE T. HAISB1 MIIIIS SALES EET5IHEBR ALLIS GHALMBBS OOMPASY ST. LOUIS, MISSOURI Presented to the College...

Hansen, George T.

1911-01-01T23:59:59.000Z

140

Polo-like Kinase I is involved in Invasion through Extracellular Matrix  

SciTech Connect (OSTI)

Polo-like kinase 1, PLK1, has important functions in maintaining genome stability and is involved in regulation of mitosis. PLK1 is up regulated in many invasive carcinomas. We asked whether it may also play a role in acquisition of invasiveness, a crucial step in transition to malignancy. In a model of metaplastic basal-like breast carcinoma progression, we found that PLK1 expression is necessary but not sufficient to induce invasiveness through laminin-rich extracellular matrix. PLK1 mediates invasion via Vimentin and {beta}1 integrin, both of which are necessary. We observed that PLK1 phosphorylates Vimentin on serine 82, which in turn regulates cell surface levels of {beta}1 integrin. We found PLK1 to be also highly expressed in pre-invasive in situ carcinomas of the breast. These results support a role for the involvement of PLK1 in the invasion process and point to this pathway as a potential therapeutic target for pre-invasive and invasive breast carcinoma treatment.

Bissell, Mina J; Rizki, Aylin; Mott, Joni D.; Bissell, Mina J

2008-04-02T23:59:59.000Z

Note: This page contains sample records for the topic "involvement involvement involvement" from the National Library of EnergyBeta (NLEBeta).
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141

Pseudobond parameters for QM/MM studies involving nucleosides, nucleotides, and their analogs  

SciTech Connect (OSTI)

In biological systems involving nucleosides, nucleotides, or their respective analogs, the ribose sugar moiety is the most common reaction site, for example, during DNA replication and repair. How- ever, nucleic bases, which comprise a sizable portion of nucleotide molecules, are usually unreactive during such processes. In quantum mechanical/molecular simulations of nucleic acid reactivity, it may therefore be advantageous to describe specific ribosyl or ribosyl phosphate groups quantum me- chanically and their respective nucleic bases with a molecular mechanics potential function. Here, we have extended the pseudobond approach to enable quantum mechanical/molecular mechanical simulations involving nucleotides, nucleosides, and their analogs in which the interface between the two subsystems is located between the sugar and the base, namely, the C(sp3) N(sp2) bond. The pseudobond parameters were optimized on a training set of 10 molecules representing several nu- cleotide and nucleoside bases and analogs, and they were then tested on a larger test set of 20 diverse molecules. Particular emphasis was placed on providing accurate geometries and electrostatic prop- erties, including electrostatic potential, natural bond orbital (NBO) and atoms in molecules (AIM) charges and AIM first moments. We also tested the optimized parameters on five nucleotide and nu- cleoside analogues of pharmaceutical relevance and a small polypeptide (triglycine). Accuracy was maintained for these systems, which highlights the generality and transferability of the pseudobond approach. 2013 American Institute of Physics. [http://dx.doi.org/10.1063/1.4772182

Chaudret, Robin [Duke University, North Carolina] [Duke University, North Carolina; Parks, Jerry M [ORNL] [ORNL; Yang, Weitao [Duke University, North Carolina] [Duke University, North Carolina

2013-01-01T23:59:59.000Z

142

To examine how the dynamics of recall processes are affected by the control processes involved with search termination, to study  

E-Print Network [OSTI]

involved with search termination, to study the implications of these control processes for the development at understanding the metacognitive control processes involved with the decision to terminate memory search. Specifically, research examines the impact of search termination decisions on the natural retrieval dynamics

Dougherty, Michael

143

Reduction Involving Controlled Execution Slides modified by Benny Chor, based on original slides by Maurice Herlihy, Brown University. p.1  

E-Print Network [OSTI]

Lecture 10 Reduction Involving Controlled Execution Slides modified by Benny Chor, based on original slides by Maurice Herlihy, Brown University. ­ p.1 #12;Lecture 10 Reduction Involving Controlled Execution Rice Theorem Slides modified by Benny Chor, based on original slides by Maurice Herlihy, Brown

Beimel, Amos

144

A GUIDE AND A TOOLBOX FOR PUBLIC INVOLVEMENT IN THE ASSESSMENT AND THE MANAGEMENT OF CONTAMINATED SITES  

E-Print Network [OSTI]

A GUIDE AND A TOOLBOX FOR PUBLIC INVOLVEMENT IN THE ASSESSMENT AND THE MANAGEMENT OF CONTAMINATED, franck.marot@ademe.fr Keywords: Public involvement, Stakeholder, Communication, Guide, Tool, Contaminated of the assessment and the management of a contaminated site. It is also perceived as a difficult and sometimes risky

Boyer, Edmond

145

Hydrogen Bonds Involved in Binding the Qi-site Semiquinone in the bc1 Complex, Identified through Deuterium Exchange  

E-Print Network [OSTI]

Hydrogen Bonds Involved in Binding the Qi-site Semiquinone in the bc1 Complex, Identified through them. The strength of interactions indicates that the protons are involved in hydrogen bonds with SQ. The hyperfine cou- plings differ from values typical for in-plane hydrogen bonds previously observed in model

Crofts, Antony R.

146

Involvement of calcium-sensing receptor in ischemia/reperfusion-induced apoptosis in rat cardiomyocytes  

SciTech Connect (OSTI)

The calcium-sensing receptor (CaR) is a seven-transmembrane G-protein coupled receptor, which activates intracellular effectors, for example, it causes inositol phosphate (IP) accumulation to increase the release of intracellular calcium. Although intracellular calcium overload has been implicated in the cardiac ischemia/reperfusion (I/R)-induced apoptosis, the role of CaR in the induction of apoptosis has not been fully understood. This study tested the hypothesis that CaR is involved in I/R cardiomyocyte apoptosis by increasing [Ca{sup 2+}]{sub i}. The isolated rat hearts were subjected to 40-min ischemia followed by 2 h of reperfusion, meanwhile GdCl{sub 3} was added to reperfusion solution. The expression of CaR increased at the exposure to GdCl{sub 3} during I/R. By laser confocal microscopy, it was observed that the intracellular calcium was significantly increased and exhibited a collapsed {delta}{psi} {sub m}, as monitored by 5,5',6,6'-tetrachloro-1,1',3,3'- tetraethylbenzimidazolcarbocyanine iodide (JC-1) during reperfusion with GdCl{sub 3}. Furthermore, the number of apoptotic cells was significantly increased as shown by TUNEL assay. Typical apoptotic cells were observed with transmission electron microscopy in I/R with GdCl{sub 3} but not in the control group. The expression of cytosolic cytochrome c and activated caspase-9 and caspase-3 was significantly increased whereas the expression of mitochondrial cytochrome c significantly decreased in I/R with GdCl{sub 3} in comparison to the control. In conclusion, these results suggest that CaR is involved in the induction of cardiomyocyte apoptosis during ischemia/reperfusion through activation of cytochrome c-caspase-3 signaling pathway.

Zhang Weihua [Department of Pathophysiology, Harbin Medical University, Harbin 150086 (China); Fu Songbin [Department of Genetics, Harbin Medical University, Harbin 150086 (China); Bio-pharmaceutical Key Laboratory of Heilongjiang Province, Harbin 150086 (China); Lu Fanghao [Department of Pathophysiology, Harbin Medical University, Harbin 150086 (China)]. E-mail: lufanghao1973@yahoo.com.cn; Wu Bo [Department of Pathophysiology, Harbin Medical University, Harbin 150086 (China); Gong Dongmei [Department of Pharmacology, Harbin Medical University, Harbin 150086 (China); Pan, Zhen-wei [Department of Pharmacology, Harbin Medical University, Harbin 150086 (China); Lv Yanjie [Department of Pharmacology, Harbin Medical University, Harbin 150086 (China); Zhao Yajun [Department of Pathophysiology, Harbin Medical University, Harbin 150086 (China); Li Quanfeng [Department of Pathophysiology, Harbin Medical University, Harbin 150086 (China); Wang Rui [Department of Pathophysiology, Harbin Medical University, Harbin 150086 (China); Department of Biology, Lakehead University, Thunder Bay, Ont., P7B5E1 (Canada); Yang Baofeng [Department of Pharmacology, Harbin Medical University, Harbin 150086 (China); Bio-pharmaceutical Key Laboratory of Heilongjiang Province, Harbin 150086 (China); Xu Changqing [Department of Pathophysiology, Harbin Medical University, Harbin 150086 (China) and Bio-pharmaceutical Key Laboratory of Heilongjiang Province, Harbin 150086 (China)]. E-mail: xucq@163.com

2006-09-08T23:59:59.000Z

147

Enhanced Postischemic Functional Recovery in CYP2J2 Transgenic Hearts Involves Mitochondrial ATP-Sensitive K  

E-Print Network [OSTI]

Enhanced Postischemic Functional Recovery in CYP2J2 Transgenic Hearts Involves Mitochondrial ATP the improved postischemic LVDP recovery in CYP2J2 Tr hearts. Perfusion with the ATP-sensitive K channel (KATP

Hammock, Bruce D.

148

Community Involvement in the Preservation of World Heritage Sites: The Case of the Ukrainian Carpathian Wooden Churches  

E-Print Network [OSTI]

Encouraging the participation of the local population in the preservation of World Heritage Sites is one of the missions of UNESCOs World Heritage Centre. Community involvement is also critical in the planning process. This dissertation argues...

Schneider, Hans Rainer

2013-05-30T23:59:59.000Z

149

To understand the cognitive processes involved with probability judgment, decision making, and choice, to explore the implications these processes for  

E-Print Network [OSTI]

, and choice, to explore the implications these processes for understanding real-world decision makingObjective To understand the cognitive processes involved with probability judgment, decision making at understanding the cognitive processes underlying diagnostic hypothesis generation and human judgment

Dougherty, Michael

150

Control of Major-Accident Hazards Involving Land Transmission Charlotte BOUISSOU, Project Manager for Pipelines Risk Assessment  

E-Print Network [OSTI]

Control of Major-Accident Hazards Involving Land Transmission Pipelines Charlotte BOUISSOU, Project Nicolas DECHY, Project Manager for Accidents Analysis and Learning from Experience Contact : charlotte, this Directive does not apply to land transmission pipelines... According to several accidents analysis

Paris-Sud XI, Université de

151

Supply chain management (SCM) involves the management of materials and information across the entire supply chain. This includes raw material  

E-Print Network [OSTI]

Supply chain management (SCM) involves the management of materials and information across this concentration will be required to take three core courses: Materials and Supply Chain Management, Transportation Purchasing identify global sources of materials, select vendors, and manage negotiati

Calgary, University of

152

The Effects of an Intervention to Foster a Caring and Task-Involving Climate at a University Recreation Center  

E-Print Network [OSTI]

using constructs from the POMS (depression, anxiety, fearful, fatigue, hostility; Usala & 18 Hertzog, 1989). An advantage of the instruments selected is there flexibility for the researcher to 19 indicate time frame (Pressman & Cohen, 2005...-Being, Self-Assuredness, Attentiveness) 6 were positively related to the task-involving climate. All but fatigue of the negative mood states 7 (i.e., Depressed, Anxiety, Hostility, Fearful) were positively associated to the ego-involving 8 climate...

Brown, Theresa Clare

2011-04-21T23:59:59.000Z

153

Depletion of bovine pituitary prolactin by cysteamine involves a thiol:disulfide mechanism  

SciTech Connect (OSTI)

Cysteamine (2-aminoethanethiol (CySH)) reduces measurable PRL concentrations in vivo and in vitro. Since secretion is also inhibited, CySH may block conversion from a poorly assayable hormone storage form(s) to readily assayable, releasable PRL. This would represent a previously unrecognized mechanism for secretory regulation. We undertook the present study to identify the sites involved in the loss of measurable PRL (depletion) induced by cysteamine. The disulfide cystamine was ineffective on secretory granules unless combined with reduced glutathione, indicating the generation of the active CySH-thiol form. Pretreatment of granules with thiol-blocking agents resulted in dose-dependent enhancement of CySH inhibition, achieving nearly complete inhibition with 5 mM iodoacetamide. In contrast, pretreatment with reduced glutathione or dithiothreitol, respectively, impaired or abolished the CySH effect. These data suggest that the mechanism by which CySH causes PRL depletion is mediated by granule disulfides and the -SH of CySH. The regulation of thiol:disulfide equilibria appears to be an important determinant of the detectability of PRL storage forms and of their secretion.

Lorenson, M.Y.; Jacobs, L.S.

1984-10-01T23:59:59.000Z

154

Risk of Developing Cardiovascular Disease After Involved Node Radiotherapy Versus Mantle Field for Hodgkin Lymphoma  

SciTech Connect (OSTI)

Purpose: Hodgkin lymphoma (HL) survivors are known to have increased cardiac mortality and morbidity. The risk of developing cardiovascular disease after involved node radiotherapy (INRT) is currently unresolved, inasmuch as present clinical data are derived from patients treated with the outdated mantle field (MF) technique. Methods and Materials: We included all adolescents and young adults with supradiaphragmatic, clinical Stage I-II HL treated at our institution from 2006 to 2010 (29 patients). All patients were treated with chemotherapy and INRT to 30 to 36 Gy. We then simulated a MF plan for each patient with a prescribed dose of 36 Gy. A logistic dose-response curve for the 25-year absolute excess risk of cardiovascular disease was derived and applied to each patient using the individual dose-volume histograms. Results: The mean doses to the heart, four heart valves, and coronary arteries were significantly lower for INRT than for MF treatment. However, the range in doses with INRT treatment was substantial, and for a subgroup of patients, with lymphoma below the fourth thoracic vertebrae, we estimated a 25-year absolute excess risk of any cardiac event of as much as 5.1%. Conclusions: Our study demonstrates a potential for individualizing treatment by selecting the patients for whom INRT provides sufficient cardiac protection for current technology; and a subgroup of patients, who still receive high cardiac doses, who would benefit from more advanced radiation technique.

Maraldo, Maja V., E-mail: dra.maraldo@gmail.com [Department of Radiation Oncology, Rigshospitalet, Copenhagen (Denmark); Brodin, Nils Patrik; Vogelius, Ivan R.; Aznar, Marianne C.; Munck af Rosenschoeld, Per; Petersen, Peter M. [Department of Radiation Oncology, Rigshospitalet, Copenhagen (Denmark); Specht, Lena [Department of Radiation Oncology, Rigshospitalet, Copenhagen (Denmark); Faculty of Health Sciences, University of Copenhagen, Copenhagen (Denmark)

2012-07-15T23:59:59.000Z

155

Elementary Act of Consciousness or Cycle of Mind, involving Distant and Nonlocal Interaction  

E-Print Network [OSTI]

Each macroscopic process can be subdivided on the quantum and classical stages. Particularly, the quantum stages of Cycle of Mind involves:1) the stimulation of dynamic correlation between water clusters in the same and remote microtubules (MTs) in state of mesoscopic Bose condensation (mBC) by phonons (acoustic waves) and by librational IR photons (electromagnetic-EM waves) distant exchange; 2) the transition from distant EM interaction between remote MTs to nonlocal quantum interaction, induced by IR photons exchange between clusters, the clusters Virtual Replicas multiplication (VRM) and virtual guides (VirG) formation between elementary particles of remote coherent water molecules. This process represents transition from mesoscopic Bose condensation to macroscopic nonuniform semi-virtual Bose condensation (VirBC) (Kaivarainen, 2006, http://arxiv.org/abs/physics/0207027); 3) the collapsing of corresponding macroscopic wave function, as a result of the optical bistability of the entangled water clusters and their disassembly due to librational photons pumping, shifting clusters to less stable state; 4) turning the clusterphilic interaction between water clusters in the open state of cavities between alpha and beta tubulins to hydrophobic one and the in-phase shift of these cavities to the closed state due to clusters disassembly (Kaivarainen, http://arxiv.org/abs/physics/0102086). The classical stages of our Hierarchic model of elementary act of Cycle of Mind are analyzed in detail.

Alex Kaivarainen

2007-09-11T23:59:59.000Z

156

A highway accident involving unirradiated nuclear fuel in Springfield, Massachusetts, on December 16, 1991  

SciTech Connect (OSTI)

In the early morning of Dec. 16, 1991, a severe accident occurred when a passenger vehicle traveling in the wrong direction collided with a tractor trailer carrying 24 unirradiated nuclear fuel assemblies in 12 containers on Interstate I-91 in Springfield, Massachusetts. The purpose of this report is to document the mechanical circumstances of the severe accident, confirm the nature and quantity of the radioactive materials involved, and assess the physical environment to which the containers were exposed and the response of the containers and their contents. The report consists of five major sections. The first section describes the circumstances and conditions of the accident and the finding of facts. The second describes the containers, the unirradiated nuclear fuel assemblies, and the tie down arrangement used for the trailer. The third describes the damage sustained during the accident to the tractor, trailer, containers, and unirradiated nuclear fuel assemblies. The fourth evaluates the accident environment and its effects on the containers and their contents. The final section gives conclusions derived from the analysis and fact finding investigation. During this severe accident, only minor injuries occurred, and at no time was the public health and safety at risk.

Carlson, R.W.; Fischer, L.E. [Lawrence Livermore National Lab., CA (United States)

1992-06-01T23:59:59.000Z

157

Talking about living and dying with the oldest old: public involvement in a study on end of life care in care homes.  

E-Print Network [OSTI]

, governance and safeguarding, and the discussion and interpretation of emergent findings with the older people living in the care homes. PPI as collaborators in the recruitment process Recruitment to the study was a staged process, that involved securing care... expressed doubts about participation Table 1 Public involvement in different stages of research process PIR Involvement Level of Involvement Study Design Input on grant proposal and development of method for public involvement within the study Steering...

Goodman, Claire; Mathie, Elspeth; Cowe, Marion; Mendoza, Alex; Westwood, Daphne; Munday, Diane; Wilson, Patricia M; Crang, Clare; Froggatt, Katherine; Iliffe, Steve; Manthorpe, Jill; Gage, Heather; Barclay, Stephen

2011-11-23T23:59:59.000Z

158

Photoinduced and thermal reactions involving hydrogen in high-germania-core optical fibres  

SciTech Connect (OSTI)

We report a Raman scattering study of photoinduced and thermal reactions between H{sub 2} and germanosilicate optical fibres with 22 mol % and 97 mol % GeO{sub 2} in the core (F1 and F2, respectively) after H{sub 2} loading at 150 MPa (1500 atm). The mechanisms of photoreactions are investigated in a wide range of incident laser wavelengths (244, 333, 354, 361 and 514 nm). Thermal reactions are studied at 500 {sup 0}C. The results indicate that the main mechanism behind the formation of hydrogen-containing defects with Raman bands at 700, 750, 2190, 3600 and 3680 cm{sup -1} involves {identical_to}Ge-O-Ge{identical_to} or {identical_to}Ge-O-Si{identical_to} bond breaking and formation of hydride and hydroxyl species: =GeH{sub 2} (700, 750 cm{sup -1}), {identical_to}Ge-H (2190 cm{sup -1}), {identical_to}GeO-H (3600 cm{sup -1}) and {identical_to}SiO-H (3680 cm{sup -1}). The key features of the reactions in the F1 and F2 fibres are analysed. In particular, photoinduced reactions give {identical_to}Si-OH groups only in the F1 fibres, whereas the formation of germanium nanoclusters at a relatively low temperature ({approx}500 {sup 0}C) or {identical_to}GeO-H and {identical_to}Ge-H defects under 514-nm irradiation has only been observed in the F2 fibres. (optical fibres)

Rybaltovskii, A O [Skobeltsyn Institute of Nuclear Physics, Lomonosov Moscow State University, Moscow (Russian Federation); Koltashev, V V; Medvedkov, O I; Rybaltovsky, A A; Sokolov, V O; Plotnichenko, V G; Dianov, Evgenii M [Fiber Optics Research Center, Russian Academy of Sciences, Moscow (Russian Federation); Klyamkin, Semen N [Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow (Russian Federation)

2008-12-31T23:59:59.000Z

159

Issues Involving The OSI Concept of Operation For Noble Gas Radionuclide Detection  

SciTech Connect (OSTI)

The development of a technically sound protocol for detecting the subsurface release of noble gas radionuclides is critical to the successful operation of an on site inspection (OSI) under the CTBT and has broad ramifications for all aspects of the OSI regime including the setting of specifications for both sampling and analysis equipment used during an OSI. With NA-24 support, we are investigating a variety of issues and concerns that have significant bearing on policy development and technical guidance regarding the detection of noble gases and the creation of a technically justifiable OSI concept of operation. The work at LLNL focuses on optimizing the ability to capture radioactive noble gases subject to the constraints of possible OSI scenarios. This focus results from recognizing the difficulty of detecting gas releases in geologic environments - a lesson we learned previously from the LLNL Non-Proliferation Experiment (NPE). Evaluation of a number of important noble gas detection issues, potentially affecting OSI policy, has awaited the US re-engagement with the OSI technical community. Thus, there have been numerous issues to address during the past 18 months. Most of our evaluations of a sampling or transport issue necessarily involve computer simulations. This is partly due to the lack of OSI-relevant field data, such as that provided by the NPE, and partly a result of the ability of LLNL computer-based models to test a range of geologic and atmospheric scenarios far beyond what could ever be studied in the field making this approach very highly cost effective. We review some highlights of the transport and sampling issues we have investigated during the past year. We complete the discussion of these issues with a description of a preliminary design for subsurface sampling that is intended to be a practical solution to most if not all the challenges addressed here.

Carrigan, C R; Sun, Y

2011-01-21T23:59:59.000Z

160

Involvement of nuclear factor {kappa}B in platelet CD40 signaling  

SciTech Connect (OSTI)

Highlights: Black-Right-Pointing-Pointer sCD40L induces TRAF2 association to CD40 and NF-{kappa}B activation in platelets. Black-Right-Pointing-Pointer I{kappa}B{alpha} phosphorylation downstream of CD40L/CD40 signaling is independent of p38 MAPK phosphorylation. Black-Right-Pointing-Pointer I{kappa}B{alpha} is required for sCD40L-induced platelet activation and potentiation of aggregation. -- Abstract: CD40 ligand (CD40L) is a thrombo-inflammatory molecule that predicts cardiovascular events. Platelets constitute the major source of soluble CD40L (sCD40L), which has been shown to potentiate platelet activation and aggregation, in a CD40-dependent manner, via p38 mitogen activated protein kinase (MAPK) and Rac1 signaling. In many cells, the CD40L/CD40 dyad also induces activation of nuclear factor kappa B (NF-{kappa}B). Given that platelets contain NF-{kappa}B, we hypothesized that it may be involved in platelet CD40 signaling and function. In human platelets, sCD40L induces association of CD40 with its adaptor protein the tumor necrosis factor receptor associated factor 2 and triggers phosphorylation of I{kappa}B{alpha}, which are abolished by CD40L blockade. Inhibition of I{kappa}B{alpha} phosphorylation reverses sCD40L-induced I{kappa}B{alpha} phosphorylation without affecting p38 MAPK phosphorylation. On the other hand, inhibition of p38 MAPK phosphorylation has no effect on I{kappa}B{alpha} phosphorylation, indicating a divergence in the signaling pathway originating from CD40 upon its ligation. In functional studies, inhibition of I{kappa}B{alpha} phosphorylation reverses sCD40L-induced platelet activation and potentiation of platelet aggregation in response to a sub-threshold concentration of collagen. This study demonstrates that the sCD40L/CD40 axis triggers NF-{kappa}B activation in platelets. This signaling pathway plays a critical role in platelet activation and aggregation upon sCD40L stimulation and may represent an important target against thrombo-inflammatory disorders.

Hachem, Ahmed [Laboratory of Thrombosis and Hemostasis, Montreal Heart Institute, 5000 Belanger, Montreal, Quebec, Canada H1T 1C8 (Canada)] [Laboratory of Thrombosis and Hemostasis, Montreal Heart Institute, 5000 Belanger, Montreal, Quebec, Canada H1T 1C8 (Canada); Yacoub, Daniel [Laboratory of Thrombosis and Hemostasis, Montreal Heart Institute, 5000 Belanger, Montreal, Quebec, Canada H1T 1C8 (Canada) [Laboratory of Thrombosis and Hemostasis, Montreal Heart Institute, 5000 Belanger, Montreal, Quebec, Canada H1T 1C8 (Canada); Centre Hospitalier Universite de Montreal, 264 boul. Rene-Levesque est, Montreal, Quebec, Canada H2X 1P1 (Canada); Zaid, Younes [Laboratory of Thrombosis and Hemostasis, Montreal Heart Institute, 5000 Belanger, Montreal, Quebec, Canada H1T 1C8 (Canada)] [Laboratory of Thrombosis and Hemostasis, Montreal Heart Institute, 5000 Belanger, Montreal, Quebec, Canada H1T 1C8 (Canada); Mourad, Walid [Universite de Montreal, Department of Medicine, 2900 boul. Edouard-Montpetit, Montreal, Quebec, Canada H3T 1J4 (Canada) [Universite de Montreal, Department of Medicine, 2900 boul. Edouard-Montpetit, Montreal, Quebec, Canada H3T 1J4 (Canada); Centre Hospitalier Universite de Montreal, 264 boul. Rene-Levesque est, Montreal, Quebec, Canada H2X 1P1 (Canada); Merhi, Yahye, E-mail: yahye.merhi@icm-mhi.org [Laboratory of Thrombosis and Hemostasis, Montreal Heart Institute, 5000 Belanger, Montreal, Quebec, Canada H1T 1C8 (Canada) [Laboratory of Thrombosis and Hemostasis, Montreal Heart Institute, 5000 Belanger, Montreal, Quebec, Canada H1T 1C8 (Canada); Universite de Montreal, Department of Medicine, 2900 boul. Edouard-Montpetit, Montreal, Quebec, Canada H3T 1J4 (Canada)

2012-08-17T23:59:59.000Z

Note: This page contains sample records for the topic "involvement involvement involvement" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


161

Public Involvement Plan Public Involvement Plan  

Broader source: Energy.gov (indexed) [DOE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "ofEarly Careerlumens_placard-green.epsEnergy1.pdfMarket37963 Vol. 79, No.and/or localNuclearReports

162

Report on International Collaboration Involving the FE Heater and HG-A Tests at Mont Terri  

SciTech Connect (OSTI)

Nuclear waste programs outside of the US have focused on different host rock types for geological disposal of high-level radioactive waste. Several countries, including France, Switzerland, Belgium, and Japan are exploring the possibility of waste disposal in shale and other clay-rich rock that fall within the general classification of argillaceous rock. This rock type is also of interest for the US program because the US has extensive sedimentary basins containing large deposits of argillaceous rock. LBNL, as part of the DOE-NE Used Fuel Disposition Campaign, is collaborating on some of the underground research laboratory (URL) activities at the Mont Terri URL near Saint-Ursanne, Switzerland. The Mont Terri project, which began in 1995, has developed a URL at a depth of about 300 m in a stiff clay formation called the Opalinus Clay. Our current collaboration efforts include two test modeling activities for the FE heater test and the HG-A leak-off test. This report documents results concerning our current modeling of these field tests. The overall objectives of these activities include an improved understanding of and advanced relevant modeling capabilities for EDZ evolution in clay repositories and the associated coupled processes, and to develop a technical basis for the maximum allowable temperature for a clay repository. The R&D activities documented in this report are part of the work package of natural system evaluation and tool development that directly supports the following Used Fuel Disposition Campaign (UFDC) objectives: ? Develop a fundamental understanding of disposal-system performance in a range of environments for potential wastes that could arise from future nuclear-fuel-cycle alternatives through theory, simulation, testing, and experimentation. ? Develop a computational modeling capability for the performance of storage and disposal options for a range of fuel-cycle alternatives, evolving from generic models to more robust models of performance assessment. For the purpose of validating modeling capabilities for thermal-hydro-mechanical (THM) processes, we developed a suite of simulation models for the planned full-scale FE Experiment to be conducted in the Mont Terri URL, including a full three-dimensional model that will be used for direct comparison to experimental data once available. We performed for the first time a THM analysis involving the Barcelona Basic Model (BBM) in a full three-dimensional field setting for modeling the geomechanical behavior of the buffer material and its interaction with the argillaceous host rock. We have simulated a well defined benchmark that will be used for codeto- code verification against modeling results from other international modeling teams. The analysis highlights the complex coupled geomechanical behavior in the buffer and its interaction with the surrounding rock and the importance of a well characterized buffer material in terms of THM properties. A new geomechanical fracture-damage model, TOUGH-RBSN, was applied to investigate damage behavior in the ongoing HG-A test at Mont Terri URL. Two model modifications have been implemented so that the Rigid-Body-Spring-Network (RBSN) model can be used for analysis of fracturing around the HG-A microtunnel. These modifications are (1) a methodology to compute fracture generation under compressive stress conditions and (2) a method to represent anisotropic elastic and strength properties. The method for computing fracture generation under compressive load produces results that roughly follow trends expected for homogeneous and layered systems. Anisotropic properties for the bulk rock were represented in the RBSN model using layered heterogeneity and gave bulk material responses in line with expectations. These model improvements were implemented for an initial model of fracture damage at the HG-A test. While the HG-A test model results show some similarities with the test observations, differences between the model results and observations remain.

Houseworth, Jim; Rutqvist, Jonny; Asahina, Daisuke; Chen, Fei; Vilarrasa, Victor; Liu, Hui-Hai; Birkholzer, Jens

2013-11-06T23:59:59.000Z

163

"The Greek community will strive for excellence in scholarship, service, leadership, involvement, diversity, building community, and brotherhood/sisterhood."  

E-Print Network [OSTI]

, involvement, diversity, building community, and brotherhood/sisterhood." Being sustainable or "going green professionals to develop customized green workplans. 2) Sustainable Practices - · Work as a collective 1255 students) are leading the sustainability effort on campus with their Green Greeks vision and plan

Linhardt, Robert J.

164

TERC Research in the Chilean Patagonia TERC is involved in a collaborative research effort with the EULA Center of the  

E-Print Network [OSTI]

TERC Research in the Chilean Patagonia TERC is involved in a collaborative research effort of the Chilean Patagonia. The lakes, rivers, glaciers, wetlands and other aquatic environments of the Chilean Patagonia offer a globally unique opportunity for science. They represent the most undisturbed aquatic

Schladow, S. Geoffrey

165

Most fish have a forward undulatory swimming mechanism that involves a kinematic propulsive wave travelling down the  

E-Print Network [OSTI]

Most fish have a forward undulatory swimming mechanism that involves a kinematic propulsive wave backwards in a similar way. We compared the kinematics (wave speed, cycle frequency, amplitude, local in the direction opposite to that of swimming. We observe two major kinematic differences. First, the slope of wave

D'Août, Kristiaan

166

Robotics Minor Robotics is a truly interdisciplinary minor, involving expertise in the fields of computer science, electrical  

E-Print Network [OSTI]

Robotics Minor Robotics is a truly interdisciplinary minor, involving expertise in the fields-requisites to the minor courses: Calculus I, Calculus II, Physics I, and Physics II or electricity. Robotics Minor.265 Logic Design 16.317 Microprocessors Systems Design I 22.211 Statics 22.213 Dynamics 22.579 Robotics

Massachusetts at Lowell, University of

167

Project Brief: These works, part of the project to complete the RSM and Bessemer Buildings, involve refurbishment of level 3  

E-Print Network [OSTI]

Project Brief: These works, part of the project to complete the RSM and Bessemer Buildings, involve London and acts as a focus for interdisciplinary research into nanoscale materials. It attracts academics in this field, fuelled by the prospect of a new generation of high performance materials with applications

168

Abstract--Network security against possible attacks involves making decisions under uncertainty. Not only may one be  

E-Print Network [OSTI]

], security in wireless networks [12], [13] and cyber-security [14], [15], [16]. In [17] the readers can find1 Abstract--Network security against possible attacks involves making decisions under uncertainty for a further DDoS (Distributed Denial of Service) botnet attack on servers). Due to limited defense

169

162 Electrical and Computer Engineering 163 Courses and projects that actively involve them in their own education and  

E-Print Network [OSTI]

A broad education outside of engineering and science that emphasizes the role of electrical and computer162 Electrical and Computer Engineering 163 Courses and projects that actively involve them in their own education and enhance their ability to formulate and solve real-world design and research problems

Richards-Kortum, Rebecca

170

Tank Problems Here are some additional problems involving flow in and out of a container. These kinds of problems  

E-Print Network [OSTI]

9­28­1998 Tank Problems Here are some additional problems involving flow in and out of a container­order linear equations for which you can find an integrating factor. Example. A tank contains 20 gallons of pure water. Water containing 2 pounds of dissolved yogurt per gallon enters the tank at 4 gallons per

Ikenaga, Bruce

171

A Lipid-modified Phosphoinositide-specific Phospholipase C (TcPI-PLC) Is Involved in Differentiation of Trypomastigotes to  

E-Print Network [OSTI]

A Lipid-modified Phosphoinositide-specific Phospholipase C (TcPI-PLC) Is Involved C (PI- PLC) is an important component of the inositol phos- phate/diacylglycerol signaling pathway. A newly discov- ered Trypanosoma cruzi PI-PLC (TcPI-PLC) is lipid modified in its N terminus, targeted

Singer, Randall

172

Involvement as a market segmentation strategy: segmenting the United States pleasure travel market with implications for marketing Texas tourism  

E-Print Network [OSTI]

INVOLVEMENT AS A MARKET SEGMENTATION STRATEGY: SEGMENTING THE UNITED STATES PLEASURE TRAVEL MARKET WITH IMPLICATIONS FOR MARKETING TEXAS TOURISM A Thesis by BOBBY JOE JOHNSON Submitted to the Graduate College of Texas ARM University... FOR MARKETZMS TEXAS TOURISM A Thesis by BOBBY JOE JOHNSON Approved as to style and content by Daniel R. Fesenmaier (Chairman of Committee) James Gtribling (Member) Edward Heath (Member) David D. Van Fleet (Member) Thomas . Bonn c sen (Head...

Johnson, Bobby Joe

2012-06-07T23:59:59.000Z

173

The molecular mechanisms involved in the genetic instability of the CCTG. CAGG repeats associated with myotonic dystrophy type 2  

E-Print Network [OSTI]

THE MOLECULAR MECHANISMS INVOLVED IN THE GENETIC INSTABILITY OF THE CCTG?CAGG REPEATS ASSOCIATED WITH MYOTONIC DYSTROPHY TYPE 2 A Dissertation by RUHEE J. DERE Submitted to the Office of Graduate Studies of Texas A&M University... TYPE 2 A Dissertation by RUHEE J. DERE Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements for the degree...

Dere, Ruhee J.

2006-08-16T23:59:59.000Z

174

Examining students' perceptions of study abroad programs involving sport through application of the social cognitive career theory  

E-Print Network [OSTI]

changes. In the last twenty five years, governments have contributed large sums of money towards sport succeeding on the international stage (Nauright, 2004). The International Olympic Committee and F?d?ration Internationale de Football Association... which are not affiliated to both (p. 27) Every two years, the Olympics showcase many of the world?s great athletes on a global stage. Soccer is the world?s most globalized sport, with over 200 countries involved with FIFA (Milanovic, 2005). Many...

Jones, Gregory C.

2009-06-02T23:59:59.000Z

175

Factors involved in the seasonal and geographical regulation of diapause in the boll weevil, Anthonomus grandis Boheman  

E-Print Network [OSTI]

FACTORS INVOLVED IN 'ZHE SEASONAL AND GEOGEAPNICAL EMQULATION OF DIAPAUSE Ill ttlL BOLL itl' 'VIL I~it&I UNOiliUG OtOtBDIB BOtlIIiBB A thesis by Ninfield Linsoln Sterling Submitted to the Qraduate College of Texas AM Universe. tp in Fartial... under tsy water in wxuc-bottom disseotion dishes. Elgtrae and hind wings were removed and disseotions maCe un4ex' a miorosooye at S0s image. Gne ohaxeoter used fox' the determination of 4iayause was Che hyyertroyhS of Che abdominal fat body...

Sterling, W. L

1966-01-01T23:59:59.000Z

176

Involvement and Communication Committee.  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Tank Waste Committee Chair 1 : Dirk Dunning 4 , Alternate Vice Chair 1 : Bob Suyama 4 , Member Committee Members 2 : David Bernhard Pam Larsen Al Boldt Larry Lockrem Tom Carpenter...

177

Involvement and Communication Committee.  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Budget and Contracts Committee Chair 1 : Jerry Peltier 4 , Member Vice Chair 1 : Gary Garnant 4 , Member and Gerry Pollet 4 , Member Committee Members 2 : Al Boldt Gerry Pollet...

178

Involvement and Communication Committee.  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Health, Safety, Environmental Protection Chair 1 : Becky Holland 4 , Member Vice Chair 1 : Rich Bloom 4 , Alternate Committee Members 2 : Rich Bloom John Howieson Antone Brooks...

179

Involvement and Communication Committee.  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

River and Plateau Committee Chair 1 : Pam Larsen 4 , Member Vice Chair 1 : Dale Engstrom 4 , Alternate Committee Members 2 : Jan Catrell Emmett Moore Shelley Cimon Jerry Peltier...

180

TPA Public Involvement Survey  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear Security AdministrationcontrollerNanocrystallineForeign Object DamageSystemsU.S.Energy InnovationTOj Hanford

Note: This page contains sample records for the topic "involvement involvement involvement" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


181

Involvement & Outreach  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary)morphinanInformation Desert Southwest Region service area.PortaldefaultIntroducing AuroraInvestorPages default

182

Commitment to Public Involvement  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation Proposed New SubstationClean CommunitiesEFRCInformationBaseline for FossilSuccess015

183

Parent Involvement (Spanish)  

E-Print Network [OSTI]

producidas por el servicio de Extensi?n en el Internet: http://tcebookstore.org Los programas educativos del Servicio de Extensi?n Agr?cola de Texas est?n disponibles para todas las personas, sin distinci?n de raza, color, sexo, minusvalidez, religi?n, edad...

Howard, Jeff W.

2005-05-10T23:59:59.000Z

184

A successful effort to involve stakeholders in the selection of a site for a corrective action management unit  

SciTech Connect (OSTI)

As part of the effort to clean up hazardous waste sites, Sandia National Laboratories in New Mexico (SNL/NM) adopted a novel approach to involving stakeholders in a key decision associated with its Environmental Restoration (ER) Project. The decision was where to locate a Corrective Action Management Unit (CAMU), an area designed to consolidate, store, and treat wastes generated from cleanup activities. The decision-making approach was a variation of a technique known as multiattribute utility analysis (MUA). Although MUA has rarely been undertaken during normal Project activities, it proved to be a surprisingly effective means for involving stakeholders in the decision process, generating consensus over a selected site, and enhancing public trust and understanding of Project activities. Requirements and criteria for selecting CAMU sites are provided by the Environmental Protection Agency`s (EPA`s) CAMU Final Rule (EPA 1993). Recognizing the lack of experience with the Rule and the importance of community understanding and support, the ER Project sought an approach that would allow stakeholders to participate in the site-selection process.

Conway, R. [Sandia National Labs., Albuquerque, NM (United States); Merkhofer, M.W. [Applied Decision Analysis, Inc., Menlo Park, CA (United States); Oms, E. [USDOE Albuquerque, New Mexico (United State). Kirtland Area Office

1995-12-01T23:59:59.000Z

185

Genome-Wide Identification and 3D Modeling of Proteins involved in DNA Damage Recognition and Repair (Final Report)  

SciTech Connect (OSTI)

OAK-B135 DNA Damage Recognition and Repair (DDR and R) proteins play a critical role in cellular responses to low-dose radiation and are associated with cancer. the authors have performed a systematic, genome-wide computational analysis of genomic data for human genes involved in the DDR and R process. The significant achievements of this project include: (1) Construction of the computational pipeline for searching DDR and R genes, building and validation of 3D models of proteins involved in DDR and R; (2) Functional and structural annotation of the 3D models and generation of comprehensive lists of suggested knock-out mutations; (3) Important improvement of macromolecular docking technology and its application to predict the DNA-Protein complex conformation; (4) Development of a new algorithm for improved analysis of high-density oligonucleotide arrays for gene expression profiling; (5) Construction and maintenance of the DNA Damage Recognition and Repair Database; and (6) Producing 14 research papers (10 published and 4 in preparation).

Ruben A. Abagyan, PhD

2004-04-15T23:59:59.000Z

186

Involvement of VAMP-2 in exocytosis of IL-1{beta} in turbot (Scophthalmus maximus) leukocytes after Vibrio anguillarum infection  

SciTech Connect (OSTI)

Vibrio anguillarum is a major pathogen threatening the fish aquaculture in China. Infection of cultivated turbot (Scophthalmus maximus) with V. anguillarum induced rapid synthesis and secretion of IL-1{beta}, which initiates the innate immune response. SNARE proteins are known to regulate vesicular trafficking and fusion in all eukaryotes. Here, we determined whether SNARE proteins, specifically vesicle-associated membrane protein-2 (VAMP-2), are involved in regulated exocytosis of IL-1{beta} of leukocytes in marine fish. We show that VAMP-2 is present in turbot blood leukocytes, with nucleotide sequence identity of 88.2% and 93.0% to those of zebra fish and sea bass, respectively. After Vibrio infection, turbot leukocyte VAMP-2 was increased at the levels of transcription and translation in a temporal pattern coinciding with leukocyte IL-1{beta} secretion. Confocal microscopy localized VAMP-2 to vesicle structures in leukocytes. Taken together, our results suggest that VAMP-2 is involved in regulated exocytosis of cytokines in immunocytes in fish.

Chai Yingmei [Department of Life Science, Ocean University of China, Qingdao 266003 (China); Marine Bioactive Substances Laboratory, First Institute of Oceanography, SOA, Qingdao 266061 (China); College of Marine Life Sciences, Shandong University at Weihai, Weihai 264209 (China); Huang Xiaohang [Marine Bioactive Substances Laboratory, First Institute of Oceanography, SOA, Qingdao 266061 (China)]. E-mail: xiaohanghuang@yahoo.ca; Cong Bailin [Marine Bioactive Substances Laboratory, First Institute of Oceanography, SOA, Qingdao 266061 (China); Liu Shenghao [Marine Bioactive Substances Laboratory, First Institute of Oceanography, SOA, Qingdao 266061 (China); Chen Kui [Marine Bioactive Substances Laboratory, First Institute of Oceanography, SOA, Qingdao 266061 (China); Li Guangyou [Marine Bioactive Substances Laboratory, First Institute of Oceanography, SOA, Qingdao 266061 (China); Gaisano, Herbert Y. [Department of Medicine, University of Toronto, Toronto, M5S 1A8 (Canada)

2006-04-07T23:59:59.000Z

187

The Crystal Structure and Mechanism of an Unusual Oxidoreductase, GilR, Involved in Gilvocarcin V Biosynthesis  

SciTech Connect (OSTI)

GilR is a recently identified oxidoreductase that catalyzes the terminal step of gilvocarcin V biosynthesis and is a unique enzyme that establishes the lactone core of the polyketide-derived gilvocarcin chromophore. Gilvocarcin-type compounds form a small distinct family of anticancer agents that are involved in both photo-activated DNA-alkylation and histone H3 cross-linking. High resolution crystal structures of apoGilR and GilR in complex with its substrate pregilvocarcin V reveals that GilR belongs to the small group of a relatively new type of the vanillyl-alcohol oxidase flavoprotein family characterized by bicovalently tethered cofactors. GilR was found as a dimer, with the bicovalently attached FAD cofactor mediated through His-65 and Cys-125. Subsequent mutagenesis and functional assays indicate that Tyr-445 may be involved in reaction catalysis and in mediating the covalent attachment of FAD, whereas Tyr-448 serves as an essential residue initiating the catalysis by swinging away from the active site to accommodate binding of the 6R-configured substrate and consequently abstracting the proton of the hydroxyl residue of the substrate hemiacetal 6-OH group. These studies lay the groundwork for future enzyme engineering to broaden the substrate specificity of this bottleneck enzyme of the gilvocarcin biosynthetic pathway for the development of novel anti-cancer therapeutics.

Noinaj, Nicholas; Bosserman, Mary A.; Schickli, M. Alexandra; Piszczek, Grzegorz; Kharel, Madan K.; Pahari, Pallab; Buchanan, Susan K.; Rohr, Jrgen (NIH); (Kentucky)

2012-11-26T23:59:59.000Z

188

Exploring the Genome and Proteome of Desulfitobacterium hafniense DCB2 for its Protein Complexes Involved in Metal Reduction and Dechlorination  

SciTech Connect (OSTI)

Desulfitobacteria are of interest to DOE mission because of their ability to reduce many electron acceptors including Fe(III), U(VI), Cr(VI), As(V), Mn(IV), Se(VI), NO3- and well as CO2, sulfite, fumarate and humates, their ability to colonize more stressful environments because they form spores, fix nitrogen and they have the more protective Gram positive cell walls. Furthermore at least some of them reductively dechlorinate aromatic and aliphatic pollutants. Importantly, most of the metals and the organochlorine reductions are coupled to ATP production and support growth providing for the organism's natural selection at DOE's contaminant sites. This work was undertaken to gain insight into the genetic and metabolic pathways involved in dissimilatory metal reduction and reductive dechlorination, (ii) to discern the commonalities among these electron-accepting processes, (iii) to identify multi-protein complexes catalyzing these functions and (iv) to elucidate the coordination in expression of these pathways and processes.

Kim, Sang-Hoon, Christina Harzman, John K. Davis, Rachel Hutcheson, Joan B. Broderick, Terence L. Marsh, James M. Tiedje.

2012-09-27T23:59:59.000Z

189

DNA rearrangement in human follicular lymphoma can involve the 5' or the 3' region of the bcl-2 gene  

SciTech Connect (OSTI)

In most human lymphomas, the chromosome translocation t(14;18) occurs within two breakpoint clustering regions on chromosome 18, the major one at the 3' untranslated region of the bcl-2 gene and the minor one at 3' of the gene. Analysis of a panel of follicular lymphoma DNAs using probes for the first exon of the bcl-2 gene indicates that DNA rearrangements may also occur 5' to the involved bcl-2 gene. In this case the IgH locus and the bcl-2 gene are found in an order suggesting that an inversion also occurred during the translocation process. The coding region of the bcl-2 gene, however, are left intact in all cases of follicular lymphoma studied to date.

Tsujimoto, Y.; Bashir, M.M.; Givol, I.; Cossman, J.; Jaffe, E.; Croce, C.M.

1987-03-01T23:59:59.000Z

190

DOE Technical Standards List. Directory of DOE and contractor personnel involved in non-government standards activities  

SciTech Connect (OSTI)

This is a periodic report on the level of agency participation in non-Government standards activities. This technical standards list is intended to assist US Department of Energy (DOE) management and other personnel involved in the DOE technical Standards Program by identifying those participating individuals. The body of this document contains a listing of DOE employees and DOE contractors who have submitted a Record of Non-Government Standards Activity. Additional names were added from rosters supplied by non-Government standards bodies. Appendices to this document are provided to list the information by parent employment organization, by non-Government standards activity, and by the proper names of the non-Government standards organizations and committees.

NONE

1997-06-01T23:59:59.000Z

191

Structural characterization of a family of cytochromes c{sub 7} involved in Fe(III) respiration by Geobacter sulfurreducens.  

SciTech Connect (OSTI)

Periplasmic cytochromes c{sub 7} are important in electron transfer pathway(s) in Fe(III) respiration by Geobacter sulfurreducens. The genome of G. sulfurreducens encodes a family of five 10-kDa, three-heme cytochromes c{sub 7}. The sequence identity between the five proteins (designated PpcA, PpcB, PpcC, PpcD, and PpcE) varies between 45% and 77%. Here, we report the high-resolution structures of PpcC, PpcD, and PpcE determined by X-ray diffraction. This new information made it possible to compare the sequences and structures of the entire family. The triheme cores are largely conserved but are not identical. We observed changes, due to different crystal packing, in the relative positions of the hemes between two molecules in the crystal. The overall protein fold of the cytochromes is similar. The structure of PpcD differs most from that of the other homologs, which is not obvious from the sequence comparisons of the family. Interestingly, PpcD is the only cytochrome c{sub 7} within the family that has higher abundance when G. sulfurreducens is grown on insoluble Fe(III) oxide compared to ferric citrate. The structures have the highest degree of conservation around 'heme IV'; the protein surface around this heme is positively charged in all of the proteins, and therefore all cytochromes c{sub 7} could interact with similar molecules involving this region. The structures and surface characteristics of the proteins near the other two hemes, 'heme I' and 'heme III', differ within the family. The above observations suggest that each of the five cytochromes c{sub 7} could interact with its own redox partner via an interface involving the regions of heme I and/or heme III; this provides a possible rationalization for the existence of five similar proteins in G. sulfurreducens.

Pokkuluri, P. R.; Londer, Y. Y.; Yang, X.; Duke, N. E. C.; Erickson, J.; Orshonsky, V.; Johnson, G.; Schiffer, M.; Biosciences Division

2010-02-01T23:59:59.000Z

192

Three new homochiral coordination polymers involving two three-dimensional structural architectures: Syntheses, structures and magnetic properties  

SciTech Connect (OSTI)

The preparations and properties of three new homochiral three-dimensional (3D) coordination polymers, [M(D-cam)(pyz)(H{sub 2}O){sub 2}]{sub n} (M=Co (1) and Ni (2); D-H{sub 2}cam=(+) D-camphoric acid; pyz=pyrazine) and [Mn{sub 2}(D-cam){sub 2}(H{sub 2}O){sub 2}] (3), under solvothermal conditions is described. Single-crystal X-ray diffraction analyses revealed that all of compounds are homochiral 3D structure. 1 and 2 are isostructural and crystallize in the trigonal space group P3{sub 2}21, while 3 crystallizes in monoclinic space group P2{sub 1}. The structure of 1 and 2 consists of metal-D-cam helical chains which are pillared with pyrazine ligands into a 3D framework structure and 3 features a 3D homochiral framework involving one-dimensional manganese-carboxylate chains that are aligned parallel to the b axis. Magnetic susceptibility data of all compounds were collected. The findings indicate that ?{sub 2}-pyrazine dominate weak antiferromagnetic coupling within 1 and 2, while 3 exhibits antiferromagnetic behavior through the carboxylate groups of D-cam ligand. -- Graphical abstract: The preparations and properties of three new homochiral three-dimensional (3D) coordination polymers, [M(D-cam)(pyz)(H{sub 2}O){sub 2}]{sub n} (M=Co (1) and Ni (2); D-H{sub 2}cam=(+) D-camphoric acid; pyz=pyrazine) and [Mn{sub 2}(D-cam){sub 2}(H{sub 2}O){sub 2}] (3), under solvothermal conditions is described. Single-crystal X-ray diffraction analyses revealed that all of compounds are homochiral 3D structure. 1 and 2 are isostructural and crystallize in the trigonal space group P3{sub 2}21, while 3 crystallizes in monoclinic space group P2{sub 1}. The structure of 1 and 2 consists of metal-D-cam helical chains which are pillared with pyrazine ligands into a 3D framework structure and 3 features a 3D homochiral framework involving one-dimensional manganese-carboxylate chains that are aligned parallel to the b axis. Magnetic susceptibility data of all compounds were collected. The findings indicate that ?{sub 2}-pyrazine dominate weak antiferromagnetic coupling within 1 and 2, while 3 exhibits antiferromagnetic behavior through the carboxylate groups of D-cam ligand. Highlights: Three homochiral 3D coordination polymers were synthesized. 1 and 2 are 3D structure with metal-D-cam helical chains pillared by pyrazine. 3 shows a 3D homochiral framework involving 1D manganese-carboxylate chains. Magnetic data analysis indicates that 13 exhibit weak antiferromagnetic coupling.

Chao, Tzu-Ling; Yang, Chen-I., E-mail: ciyang@thu.edu.tw

2014-03-15T23:59:59.000Z

193

DOE Partnerships with States, Tribes and Other Federal Programs Help Responders Prepare for Challenges Involving Transport of Radioactive Materials  

SciTech Connect (OSTI)

DOE Partnerships with States, Tribes and Other Federal Programs Help Responders Prepare for Challenges Involving Transport of Radioactive Materials Implementing adequate institutional programs and validating preparedness for emergency response to radiological transportation incidents along or near U.S. Department of Energy (DOE) shipping corridors poses unique challenges to transportation operations management. Delayed or insufficient attention to State and Tribal preparedness needs may significantly impact the transportation operations schedule and budget. The DOE Transportation Emergency Preparedness Program (TEPP) has successfully used a cooperative planning process to develop strong partnerships with States, Tribes, Federal agencies and other national programs to support responder preparedness across the United States. DOE TEPP has found that building solid partnerships with key emergency response agencies ensures responders have access to the planning, training, technical expertise and assistance necessary to safely, efficiently and effectively respond to a radiological transportation accident. Through the efforts of TEPP over the past fifteen years, partnerships have resulted in States and Tribal Nations either using significant portions of the TEPP planning resources in their programs and/or adopting the Modular Emergency Response Radiological Transportation Training (MERRTT) program into their hazardous material training curriculums to prepare their fire departments, law enforcement, hazardous materials response teams, emergency management officials, public information officers and emergency medical technicians for responding to transportation incidents involving radioactive materials. In addition, through strong partnerships with Federal Agencies and other national programs TEPP provided technical expertise to support a variety of radiological response initiatives and assisted several programs with integration of the nationally recognized MERRTT program into other training venues, thus ensuring consistency of radiological response curriculums delivered to responders. This presentation will provide an overview of the steps to achieve coordination, to avoid redundancy, and to highlight several of the successful partnerships TEPP has formed with States, Tribes, Federal agencies and other national programs. Events, accident scenarios, and training where TEPP was proven to be integral in building the radiological response capabilities for first responders to actual radiological incidents are also highlighted. Participants will gain an appreciation for the collaborative efforts States and Tribes are engaging in with the DOE to ensure that responders all along the DOE transportation corridors are adequately prepared to respond to shipments of radioactive materials through their communities.

Marsha Keister

2001-02-01T23:59:59.000Z

194

Projecting Fatalities in Crashes Involving Older Drivers, 20002025, CRADA No. ORNL98-0500 Final Report  

SciTech Connect (OSTI)

At the turn of the century the 20th century that is the median age in the United States was under 30 years; America was 60% rural in nature; and there were only 36 highway fatalities all year. As we leave the 20th century behind, the route into the 21st century is very different. Intelligent cars speed down multi-lane smart highways in a nation that is 75% urban. According to the Federal Highway Administrations Highway Statistics, there are 28,000 times more vehicles on the road in 2000 than there were in 1900, and these vehicles travel about 2.6 trillion miles each year. Annual fatalities resulting from highway crashes have also increased by over 1100%. We see other changes as well. The face of America is changing. It is growing older. In 2025, persons 65 and over will make up 18.5% of the total population. The number of persons aged 85 and over is increasing more rapidly than any other age group. More importantly, the elderly are taking more trips, driving further, and continuing to drive much later in life. These conditions lead to concerns about traffic safety. Although the elderly are healthier and drive safer cars than they did just two decades ago, their frailty makes them more susceptible to injury than younger persons involved in traffic crashes of the same severity. In addition, visual, physical, and cognitive skills, all of which contribute to driving abilities, decrease with advancing age. The familiar U-shaped curve depicting the rate of fatalities per vehicle miles traveled, shows that the elderly experience a higher highway fatality rate than any other age group except teenagers. While the overall number of highway fatalities has decreased regularly since 1972, the number of fatalities of elderly travelers has continued to increase steadily. This increase is cause for concern for both the elderly driver and for other persons on the roads who migh tbe placed in danger through crashes involving elderly drivers.

Hu, Patricia S. [ORNL] [ORNL; Jones, Donald W. [ORNL] [ORNL; Reuscher, Timothy [Oak Ridge Institute for Science and Education] [Oak Ridge Institute for Science and Education; Schmoyer, Richard S. [ORNL] [ORNL; Truett, Lorena F. [ORNL] [ORNL

2000-04-01T23:59:59.000Z

195

Insights into genes involved in electricity generation in Geobacter sulfurreducens via whole genome microarray analysis of the OmcF-de cient mutant  

E-Print Network [OSTI]

Insights into genes involved in electricity generation in Geobacter sulfurreducens via whole genome Keywords: Geobacter sulfurreducens Cytochrome Microbial fuel cells Microarray Geobacter sulfurreducens effectively produces electricity in microbial fuel cells by oxidizing acetate with an electrode serving

Lovley, Derek

196

Introduction to some basic ethical orientations [1] One of the major branches of philosophy is ethics, which involves, among other things,  

E-Print Network [OSTI]

involves both components. The problem can be set up more or less as follows: there are roughly two kinds individual are less clear, and opinions among different people may diverge: is abortion permissible

Grush, Rick

197

H2-M polymorphism in mice susceptible to collagen-induced arthritis involves the peptide binding groove  

SciTech Connect (OSTI)

The ability to develop type II collagen (CII)-induced arthritis (CIA) in mice is associated with the major histocompatibility I-A gene and with as yet poorly defined regulatory molecules of the major histocompatibility complex (MHC) class II antigen processing and presentation pathway. H2-M molecules are thought to be involved in the loading of antigenic peptides into the MHC class II binding cleft. We sequenced H2-Ma, H2-Mb1, and H2-Mb2 genes from CIA-susceptible and -resistant mouse strains and identified four different Ma and Mb2 alleles, and three different Mb1 alleles defined by polymorphic residues within the predicted peptide binding groove. Most CIA-resistant mouse strains share common Ma, Mb1, and Mb2 alleles. In contrast, H2-M alleles designated Ma-III, Ma-IV, Mb1-III, and Mb2-IV could be exclusively identified in the CIA-susceptible H2{sup r} and H2{sup q} haplotypes, suggesting that allelic H2-M molecules may modulate the composition of different CII peptides loaded onto MHC class II molecules, presumably presenting {open_quotes}arthritogenic{close_quotes} epitopes to T lymphocytes. 42 refs., 4 figs., 3 tabs.

Walter, W.; Loos, M.; Maeurer, M.J. [Johannes Gutenberg Univ., Mainz (Germany)] [Johannes Gutenberg Univ., Mainz (Germany)

1996-12-31T23:59:59.000Z

198

G-protein-coupled estrogen receptor 1 is involved in brain development during zebrafish (Danio rerio) embryogenesis  

SciTech Connect (OSTI)

Highlights: The Gper expression was detected in the developing brain of zebrafish. Gper morpholino knockdown induced apoptosis of brain cells. Gper morpholino knockdown reduced expression in neuron markers. Zebrafish Gper may be involved in neuronal development. -- Abstract: G-protein-coupled estrogen receptor 1 (Gper, formerly known as GPR30) is found to be a trophic and protective factor in mediating action of estrogen in adult brain, while its role in developing brain remains to be elucidated. Here we present the expression pattern of Gper and its functions during embryogenesis in zebrafish. Both the mRNA and protein of Gper were detected throughout embryogenesis. Whole mount in situ hybridization (WISH) revealed a wide distribution of gper mRNAs in various regions of the developing brain. Gper knockdown by specific morpholinos resulted in growth retardation in embryos and morphological defects in the developing brain. In addition, induced apoptosis, decreased proliferation of the brain cells and maldevelopment of sensory and motor neurons were also found in the morphants. Our results provide novel insights into Gper functions in the developing brain, revealing that Gper can maintain the survival of the brain cells, and formation and/or differentiation of the sensory and motor neurons.

Shi, Yanan; Liu, Xiaochun [State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals and Guangdong Provincial Key Laboratory for Aquatic Economic Animals, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275 (China)] [State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals and Guangdong Provincial Key Laboratory for Aquatic Economic Animals, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275 (China); Zhu, Pei; Li, Jianzhen; Sham, Kathy W.Y. [School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong (China)] [School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong (China); Cheng, Shuk Han [Department of Biology and Chemistry, City University of Hong Kong, Kowloon, Hong Kong (China)] [Department of Biology and Chemistry, City University of Hong Kong, Kowloon, Hong Kong (China); Li, Shuisheng; Zhang, Yong [State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals and Guangdong Provincial Key Laboratory for Aquatic Economic Animals, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275 (China)] [State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals and Guangdong Provincial Key Laboratory for Aquatic Economic Animals, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275 (China); Cheng, Christopher H.K., E-mail: chkcheng@cuhk.edu.hk [School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong (China); Lin, Haoran, E-mail: lsslhr@mail.sysu.edu.cn [State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals and Guangdong Provincial Key Laboratory for Aquatic Economic Animals, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275 (China) [State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals and Guangdong Provincial Key Laboratory for Aquatic Economic Animals, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275 (China); College of Ocean, Hainan University, Haikou 570228, Hainan (China)

2013-05-24T23:59:59.000Z

199

Conformation Changes N-terminal Involvement and cGMP Signal Relay in the Phosphodiesterase-5 GAF Domain  

SciTech Connect (OSTI)

The activity of phosphodiesterase-5 (PDE5) is specific for cGMP and is regulated by cGMP binding to GAF-A in its regulatory domain. To better understand the regulatory mechanism, x-ray crystallographic and biochemical studies were performed on constructs of human PDE5A1 containing the N-terminal phosphorylation segment, GAF-A, and GAF-B. Superposition of this unliganded GAF-A with the previously reported NMR structure of cGMP-bound PDE5 revealed dramatic conformational differences and suggested that helix H4 and strand B3 probably serve as two lids to gate the cGMP-binding pocket in GAF-A. The structure also identified an interfacial region among GAF-A, GAF-B, and the N-terminal loop, which may serve as a relay of the cGMP signal from GAF-A to GAF-B. N-terminal loop 98-147 was physically associated with GAF-B domains of the dimer. Biochemical analyses showed an inhibitory effect of this loop on cGMP binding and its involvement in the cGMP-induced conformation changes.

H Wang; H Robinson; H Ke

2011-12-31T23:59:59.000Z

200

Calculation of absorption spectra involving multiple excited states: Approximate methods based on the mixed quantum classical Liouville equation  

SciTech Connect (OSTI)

We investigate the calculation of absorption spectra based on the mixed quantum classical Liouville equation (MQCL) methods. It has been shown previously that, for a single excited state, the averaged classical dynamics approach to calculate the linear and nonlinear spectroscopy can be derived using the MQCL formalism. This work focuses on problems involving multiple coupled excited state surfaces, such as in molecular aggregates and in the cases of coupled electronic states. A new equation of motion to calculate the dipole-dipole correlation functions within the MQCL formalism is first presented. Two approximate methods are then proposed to solve the resulted equations of motion. The first approximation results in a mean field approach, where the nuclear dynamics is governed by averaged forces depending on the instantaneous electronic states. A modification to the mean field approach based on first order moment expansion is also proposed. Numerical examples including calculation of the absorption spectra of Frenkel exciton models of molecular aggregates, and the pyrazine molecule are presented.

Bai, Shuming; Xie, Weiwei; Zhu, Lili; Shi, Qiang, E-mail: qshi@iccas.ac.cn [Beijing National Laboratory for Molecular Sciences, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Institute of Chemistry, Chinese Academy of Sciences, Zhongguancun, Beijing 100190 (China)] [Beijing National Laboratory for Molecular Sciences, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Institute of Chemistry, Chinese Academy of Sciences, Zhongguancun, Beijing 100190 (China)

2014-02-28T23:59:59.000Z

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201

Visible light stimulating dual-wavelength emission and O vacancy involved energy transfer behavior in luminescence for coaxial nanocable arrays  

SciTech Connect (OSTI)

We report a strategy to investigate O vacancy (V{sub O}) involved energy transfer and dual-wavelength yellow emission in coaxial nanocable. By electric field deposition and subsequent sol-gel template approach, ZnO:Tb/Y{sub 2}O{sub 3}:Eu coaxial nanocable arrays are synthesized. After visible light excitation, system is promoted to O vacancy charge transfer state of V{sub O}(0/+). In the following cross relaxation, energy transfer from V{sub O} to the excitation energy level of Tb{sup 3+} in ZnO:Tb core area. While in Y{sub 2}O{sub 3}:Eu shell area, energy transfer to the excitation energy level of Eu{sup 3+}. Subsequently, dual-wavelength emission is observed. By constructing nanocable with dual-wavelength emission, yellow luminescence is obtained. Adjust doping concentration of Eu{sup 3+} or Tb{sup 3+} in the range of 0.010.05, chromaticity coordinates of ZnO:Tb/Y{sub 2}O{sub 3}:Eu nanocable stably stays at yellow region in color space except ZnO:Tb{sub 0.01}/Y{sub 2}O{sub 3}:Eu{sub 0.01}. As Vo states act as media in energy transfer process in nanocablers, visible light can stimulate dual-wavelength emissions. Yellow luminescent nanocable arrays will have great applications in light-emitting diode luminescence.

Yang, Lei, E-mail: nanoyang@qq.com [College of Materials Science and Engineering, Hunan University, Changsha 410082 (China); Hunan Province Key Laboratory for Spray Deposition Technology and Application, Hunan University, Changsha 410082 (China); Dong, Jiazhang; Jiang, Zhongcheng [College of Materials Science and Engineering, Hunan University, Changsha 410082 (China); Pan, Anlian; Zhuang, Xiujuan [Key Laboratory for Micro-Nano Physics and Technology of Hunan Province, Hunan University, Changsha 410082 (China)

2014-06-14T23:59:59.000Z

202

ATP-binding cassette-like transporters are involved in the transport of lignin precursors across plasma and vacuolar membranes  

SciTech Connect (OSTI)

Lignin is a complex biopolymer derived primarily from the condensation of three monomeric precursors, the monolignols. The synthesis of monolignols occurs in the cytoplasm. To reach the cell wall where they are oxidized and polymerized, they must be transported across the cell membrane. However, the molecular mechanisms underlying the transport process are unclear. There are conflicting views about whether the transport of these precursors occurs by passive diffusion or is an energized active process; further, we know little about what chemical forms are required. Using isolated plasma and vacuolar membrane vesicles prepared from Arabidopsis, together with applying different transporter inhibitors in the assays, we examined the uptake of monolignols and their derivatives by these native membrane vesicles. We demonstrate that the transport of lignin precursors across plasmalemma and their sequestration into vacuoles are ATP-dependent primary-transport processes, involving ATP-binding cassette-like transporters. Moreover, we show that both plasma and vacuolar membrane vesicles selectively transport different forms of lignin precursors. In the presence of ATP, the inverted plasma membrane vesicles preferentially take up monolignol aglycones, whereas the vacuolar vesicles are more specific for glucoconjugates, suggesting that the different ATP-binding cassette-like transporters recognize different chemical forms in conveying them to distinct sites, and that glucosylation of monolignols is necessary for their vacuolar storage but not required for direct transport into the cell wall in Arabidopsis.

Miao, Y.C.; Liu, C.

2010-12-28T23:59:59.000Z

203

Molecular cloning and sequence of the thdF gene involved in the thiophene and furan oxidation by Escherichia coli  

SciTech Connect (OSTI)

Since sulfur dioxide emission from burning high sulfur coals is a major contributor to acid rain, it is important to develop bacteria which are capable of efficiently removing the sulfur from coal before combustion. Inorganic sulfur can be removed from coal by certain strains of Thiobacillus or Sulfolobus; however the organic sulfur remains intransigent. Since high sulfur Illinois coals typically contain 60% to 70% of their sulfur in the form of the heterocyclic thiophene ring we have started to investigate the biodegradation of derivatives of thiophene and the corresponding oxygen heterocycle, furan. Our previous work resulted in the isolation of a triple mutant, NAR30, capable of oxidizing a range of furan and thiophene derivatives. However, NAR30 does not completely degrade thiophenes or furans and its oxidation of these compounds is slow and inefficient. We decided to clone the thd genes both in order to increase the efficiency of degradation and to investigate the nature of the reactions involved. 37 refs., 4 figs., 3 tabs.

Alam, K.Y.; Clark, D.P.

1990-01-01T23:59:59.000Z

204

Botryllus schlosseri (Tunicata) whole colony irradiation: Do senescent zooid resorption and immunological resorption involve similar recognition events  

SciTech Connect (OSTI)

The colonial tunicate Botryllus schlosseri undergoes cyclic blastogenesis where feeding zooids are senescened and resorbed and a new generation of zooids takes over the colony. When non-identical colonies come into direct contact, they either reject each other or fuse. Fusion is usually followed by the resorption of one of the partners in the chimera (immunological resorption). The striking morphological similarities between the two resorption phenomena suggest that both may involve tissue destruction following self-nonself recognition events. Here we attempt to modify these two events by whole colony gamma irradiation assays. Three sets of experiments were performed: (1) different doses of whole colony irradiation for determination of irradiation effects (110 colonies); (2) pairs of irradiated-nonirradiated isografts of clonal replicates for the potential of reconstruction of the irradiated partners (23 pairs); (3) chimeras of irradiated-nonirradiated partners for analysis of resorption hierarchy. Mortality increased with the irradiation dose. All colonies exposed to more than 5,000 rads died within 19 days, while no colony died below 2,000 rads. The average mortality periods, in days, for doses of 6,000-8,000, 5,000, and 2,500-4,000 rads were 14.4 +/- 3.1 (n = 24), 19.8 +/- 6.0 (n = 15), and 19.6 + 5.1 (n = 22), respectively. Younger colonies (3-6 months old) may survive radiation better than older ones (more than 13 months). Many morphological alterations were recorded in irradiated colonies: ampullar contraction and/or dilation, accumulation of pigment cells within ampullae, abnormal bleeding from blood vessels, sluggish blood circulation, necrotic zones, reduction in bud number, and irregularities in zooid and system structures. With doses of 3,000-4,000 rads and above, irradiation arrested the formation of new buds and interrupted normal takeover.

Rinkevich, B.; Weissman, I.L. (Israel Oceanographic and Limnological Research, Haifa (Israel))

1990-02-01T23:59:59.000Z

205

Reaction mechanisms in aromatic hydrocarbon formation involving the C{sub 5}H{sub 5} cyclopentadienyl moiety  

SciTech Connect (OSTI)

The quantum chemical BAC-MP4 and BAC-MP2 methods have been used to investigate the reaction mechanisms leading to polycyclic aromatic hydrocarbon (PAH) ring formation. In particular the authors have determined the elementary reaction steps in the conversion of two cyclopentadienyl radicals to naphthalene. This reaction mechanism is shown to be an extension of the mechanism occurring in the H atom-assisted conversion of fulvene to benzene. The net reaction involves the formation of dihydrofulvalene, which eliminates a hydrogen atom and then rearranges to form naphthalene through a series of ring closures and openings. The importance of forming the {single_bond}CR({center_dot}){single_bond}CHR{single_bond}CR{prime}{double_bond}CR{double_prime}-moiety, which can undergo rearrangement to form three-carbon-atom ring structures, is illustrated with the C{sub 4}H{sub 7} system. The ability of hydrogen atoms to migrate around the cyclopentadienyl moiety is illustrated both for methyl-cyclopentadiene, C{sub 5}H{sub 5}CH{sub 3}, and dihydrofulvalene, C{sub 5}H{sub 5}C{sub 5}H{sub 5}, as well as for their radical species, C{sub 6}H{sub 7} and C{sub 5}H{sub 5}C{sub 5}H{sub 4}. The mobility of hydrogen in the cyclopentadienyl moiety plays an important role both in providing resonance-stabilized radical products and in creating the {single_bond}CR({center_dot}){single_bond}CHR{single_bond}CR{prime}{double_bond}CR{double_prime}-moiety for ring formation. The results illustrate the radical pathway for converting five-membered rings to aromatic six-membered rings. Furthermore, the results indicate the important catalytic role of H atoms in the aromatic ring formation process.

Melius, C.F.; Colvin, M.E. [Sandia National Labs., Livermore, CA (United States); Marinov, N.M.; Pitz, W.J. [Lawrence Livermore National Lab., CA (United States); Senkan, S.M. [Univ. of California, Los Angeles, CA (United States). Dept. of Chemical Engineering

1996-02-01T23:59:59.000Z

206

Investigation of transport process involved in FGD. Final technical report for the third year, September 1992--August 1993  

SciTech Connect (OSTI)

This report describes the work done in the third year of the project {open_quotes}Investigation of Transport Processes Involved in FGD{close_quotes}. The objectives of this five year plan of study is to experimentally obtain a basic understanding of (1) turbulent flow structure of the mixing zone and its influence on particle dispersion, (2) the effect of particle loading on turbulent properties and mixing, (3) the effect of jet entrainment, (4) water spray-sorbent interaction, sorbent wetting and mixing, (5) investigate the flow field where certain ratios of jet velocity to flue gas velocity result in regions of negative flow and define onset of negative flow (6) sorbent reactivity in mixing zone and (7) effect of particle agglomeration. In the first two years of the project a sorbent injection facility which can simulate the conditions encountered in COOLSIDE set up was designed and built. Non-intrusive laser based diagnostic tools PDA/LDA was used for flow characterization of particle laden jet in cocurrent flows. All tasks for third year were addressed. The accomplishments for the third year include the following. For the investigation of Lime Laden Jet Flow, since no existing technique was capable of providing the simultaneous measurement of irregular shaped particle size and velocity, a new technique, TTLDV which utilizes the transit time in LDV measurement volume and the LDV velocity measurements to obtain simultaneous particle size and velocity measurements was developed. Better Sorbent Injection Methods and Optimized Injection Schemse were investigated. Progress was made in the development of Technique to Study Particulate Droplet Interactions, the task was not completed because of difficulties encountered due to differences in the refractive index of glass beads and water droplets. The investigations of flow reversal resulting from spray jet cocurrent flow interactions was completed.

Kadambi, J.R.; Kadaba, V.; Yurteri, C.

1993-09-01T23:59:59.000Z

207

Technical advantages and political necessity of public involvement in environmental remediation: The case of the U.S. and Russian weapons complexes  

SciTech Connect (OSTI)

Environmental remediation is an enormous challenge for the governments of the US, Russia, and other states in eastern and central Europe. Historically, governments have withheld issues related to nuclear weapons from public policy debate. As a result of revelations about human health impacts and environmental contamination, serious credibility problems exist for managers of weapons facilities. However, public involvement can contribute to better definition of problems, to identification of a range of potential solutions, and to increased public acceptance of outcomes. Decision makers can maximize the benefits of public involvement by integrating specific processes into their environmental remediation project planning and management.

Shideler, J.C. [JK Research Associates, Inc., Arlington, VA (United States)

1993-12-31T23:59:59.000Z

208

AN AXON'S JOURNEY TO FIND ITS PATH: IN VIVO CHARACTERIZATION OF THE MODULATORS AND EFFECTORS OF THE RAC GTPASE SIGNALING PATHWAY INVOLVED IN AXON GUIDANCE  

E-Print Network [OSTI]

and ced-10. Along with other evidence, this suggested that there were other molecules involved in the control of Rac GTPases in this process. I performed a candidate-based genetic screen in the C. elegans genome in order to find other DH-containing GEFs...

Demarco, Rafael Senos

2011-04-11T23:59:59.000Z

209

CONCLUSIONS AND RECOMMENDATIONS This report summarizes the findings of a four-year research effort involving more than 4,000  

E-Print Network [OSTI]

-year research effort involving more than 4,000 wind turbines, and aimed at better understanding bird mortality caused by existing and future wind turbines in the APWRA. We believe that the results presented here continue to be killed by wind turbines. We suggest that the rodent con

210

Involvement of ATP synthase residues aArg-376, bArg-182, and bLys-155 in Pi binding  

E-Print Network [OSTI]

Involvement of ATP synthase residues aArg-376, bArg-182, and bLys-155 in Pi binding Zulfiqar AhmadArg-182 are catalytically important ATP synthase residues that were proposed to be in- volved in substrate Pi binding and subsequent steps of ATP syn- thesis [Senior, A.E., Nadanaciva, S. and Weber, J. (2002

Zulfiqar Ahmad

211

How to connect to the University of Exeter VPN service *****Important Part of the process of using the VPN service involves the automatic  

E-Print Network [OSTI]

the VPN service involves the automatic download and installation of Juniper Network Connect software administrator rights on your computer to be able to install this software. Once this has been installed you can use it regardless of having administrator rights or not. Additionally, you can check the last page

Mumby, Peter J.

212

Imperial College London: Mental Health Difficulties Protocol, 2011 The object of this protocol is to help those involved with students in the following  

E-Print Network [OSTI]

is to help those involved with students in the following ways: 1. How to recognise mental health difficulties and academically 3. Provide information as to the relevant helping agencies Definition The term "mental health confidence and a loss of connection with reality. The combination of symptoms helps us to make a diagnosis

213

NOAA Helps the Construction Sector Build for a Changing Climate The construction industry is comprised of a wide range of business involved in engineering standards,  

E-Print Network [OSTI]

is comprised of a wide range of business involved in engineering standards, building design is needed to protect a building foundation from frost. In the past, standard foundation depths were inturn developed new insulation standards for protecting building foundations from frost. This resulted

214

The energy sector is comprised of a wide range of businesses involved in the exploration, extraction, production, refining, distribution, and sale of energy. The primary  

E-Print Network [OSTI]

, extraction, production, refining, distribution, and sale of energy. The primary industries within this sector of ways. Some examples include: · Using global surface hourly data for studies of wind energy potentialOVERVIEW The energy sector is comprised of a wide range of businesses involved in the exploration

215

Buried pipelines essentially involve problems of soil-structure interaction that include several complex factors such as geometry, material properties, and boundary  

E-Print Network [OSTI]

1 Abstract Buried pipelines essentially involve problems of soil-structure interaction that include Bend, and Buckling Check. Keywords: buried pipelines, regression, horizontal bend, vertical bend, homoscedasticity, normality. 1 Introduction Analysis and design of buried pipelines are usually based on classical

Al-Shayea, Naser Abdul-Rahman

216

Andreja Sarlah Research interests I have been involved in physical research for 4 years now. In that time I have been work-  

E-Print Network [OSTI]

. In that time I have been work- ing in the field of liquid crystals. My main research interest has been. This is what in my opinion makes the research work interesting and what gives the assuranceAndreja Sarlah Research interests I have been involved in physical research for 4 years now

Sarlah, Andreja

217

Center for Leadership and Involvement University of Wisconsin-Madison 239 Red Gym, 716 Langdon Street Phone: 608-263-0365  

E-Print Network [OSTI]

involvement as an integral part of a University education, registers over 750 student organizations, and provides services, information, education, support, advising, and interpretation of university policies evaluations are submitted. Maintain and track the grant's budget. Provide budget updates at Review Committee

Wisconsin at Madison, University of

218

The naval Research Laboratory has been actively involved in research in unmanned and autonomous systems since its opening in 1923. From one of the first unmanned  

E-Print Network [OSTI]

systems since its opening in 1923. From one of the first unmanned ground vehicles to the developmentThe naval Research Laboratory has been actively involved in research in unmanned and autonomous of more than 200 prototype air, ground, underwater, and space platforms, and from smart sensors to smart

219

Lynne Ellyn is the senior vice president and chief information officer at DTE Energy (NYSE: DTE), a Detroit-based diversified energy company involved in the development and  

E-Print Network [OSTI]

Health System Foundation, the Henry Ford Health System Quality Committee, and the DTE Energy Charitable: DTE), a Detroit-based diversified energy company involved in the development and management of energy of Management in Information Technology Advisory Board. She serves on the board of trustees of the Henry Ford

220

Early Customer Involvement in Innovation.  

E-Print Network [OSTI]

?? The Front End of innovation (FEI) or early innovation presents one of the greatest opportunities for improving an entire innovation process in any firm. (more)

Penn, Sylvain Bienvenu

2011-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "involvement involvement involvement" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


221

Political Involvement and Electoral Competition  

E-Print Network [OSTI]

Annual Review of Political Science, 7, pp. 25-46. Kendall,Conway, M. Margaret. 2000. Political participation in theand O. Listhaug. 1995. Political Sophistication and Models

De Sio, Lorenzo

2006-01-01T23:59:59.000Z

222

Cyber Incidents Involving Control Systems  

SciTech Connect (OSTI)

The Analysis Function of the US-CERT Control Systems Security Center (CSSC) at the Idaho National Laboratory (INL) has prepared this report to document cyber security incidents for use by the CSSC. The description and analysis of incidents reported herein support three CSSC tasks: establishing a business case; increasing security awareness and private and corporate participation related to enhanced cyber security of control systems; and providing informational material to support model development and prioritize activities for CSSC. The stated mission of CSSC is to reduce vulnerability of critical infrastructure to cyber attack on control systems. As stated in the Incident Management Tool Requirements (August 2005) ''Vulnerability reduction is promoted by risk analysis that tracks actual risk, emphasizes high risk, determines risk reduction as a function of countermeasures, tracks increase of risk due to external influence, and measures success of the vulnerability reduction program''. Process control and Supervisory Control and Data Acquisition (SCADA) systems, with their reliance on proprietary networks and hardware, have long been considered immune to the network attacks that have wreaked so much havoc on corporate information systems. New research indicates this confidence is misplaced--the move to open standards such as Ethernet, Transmission Control Protocol/Internet Protocol, and Web technologies is allowing hackers to take advantage of the control industry's unawareness. Much of the available information about cyber incidents represents a characterization as opposed to an analysis of events. The lack of good analyses reflects an overall weakness in reporting requirements as well as the fact that to date there have been very few serious cyber attacks on control systems. Most companies prefer not to share cyber attack incident data because of potential financial repercussions. Uniform reporting requirements will do much to make this information available to Department of Homeland Security (DHS) and others who require it. This report summarizes the rise in frequency of cyber attacks, describes the perpetrators, and identifies the means of attack. This type of analysis, when used in conjunction with vulnerability analyses, can be used to support a proactive approach to prevent cyber attacks. CSSC will use this document to evolve a standardized approach to incident reporting and analysis. This document will be updated as needed to record additional event analyses and insights regarding incident reporting. This report represents 120 cyber security incidents documented in a number of sources, including: the British Columbia Institute of Technology (BCIT) Industrial Security Incident Database, the 2003 CSI/FBI Computer Crime and Security Survey, the KEMA, Inc., Database, Lawrence Livermore National Laboratory, the Energy Incident Database, the INL Cyber Incident Database, and other open-source data. The National Memorial Institute for the Prevention of Terrorism (MIPT) database was also interrogated but, interestingly, failed to yield any cyber attack incidents. The results of this evaluation indicate that historical evidence provides insight into control system related incidents or failures; however, that the limited available information provides little support to future risk estimates. The documented case history shows that activity has increased significantly since 1988. The majority of incidents come from the Internet by way of opportunistic viruses, Trojans, and worms, but a surprisingly large number are directed acts of sabotage. A substantial number of confirmed, unconfirmed, and potential events that directly or potentially impact control systems worldwide are also identified. Twelve selected cyber incidents are presented at the end of this report as examples of the documented case studies (see Appendix B).

Robert J. Turk

2005-10-01T23:59:59.000Z

223

Safety Success Through Employee Involvement  

Broader source: Energy.gov [DOE]

Presenters: James Pollard, Monica Lewis, Michael Hendrix, Stacy Miller, Y-12 National Security Complex Track 2-2

224

Classified Visits Involving Foreign Nationals  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

The Order establishes a program to manage the Department-wide program to facilitate, document, and assure accountability when approving foreign national access to classified DOE programs and facilities. Cancels portions of Chapter VIII, of DOE O 470.1 that pertain to foreign nationals who visit DOE sitess and require access to classified information. Canceled by DOE O 470.4B.

2004-01-13T23:59:59.000Z

225

Public Involvment Plan - Rifle, Colorado  

Office of Legacy Management (LM)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "ofEarlyEnergyDepartment ofDepartment ofofOxford SiteToledo SiteTonawandaUniversity21Prepared by Oak

226

Who's Involved | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "ofEarlyEnergyDepartment ofDepartment of Energy WhileTanklessLES'NeighborhoodThisApril2014 DOE CFC

227

HOW YOU CAN BE INVOLVED  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation ProposedUsingFun with Big Sky9, 2010 The meeting was called1999Harvest84047&- MarchHOW YOU

228

Rate Adjustments and Public Involvement  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear Security Administration the1 -the Mid-Infrared at 278, 298, andEpidermal Growth Factor. | EMSLusingRate

229

Public Involvement Committee - Transcribed Flipcharts  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear Security Administration the1 - SeptemberMicroneedlesAdvanced PhotonPseudo-Single-BunchPseudogaps,PuPublicMarch 5,

230

Public Involvement Committee - Transcribed Flipcharts  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear Security Administration the1 - SeptemberMicroneedlesAdvanced PhotonPseudo-Single-BunchPseudogaps,PuPublicMarch

231

Public Involvement Committee - Transcribed Flipcharts  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear Security Administration the1 - SeptemberMicroneedlesAdvanced

232

Appendix V Public Involvement Plan  

Office of Legacy Management (LM)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "ofEarlyEnergyDepartment ofDepartment ofof EnergyYou$0.C. 20545 OCTTO:March_ ,'I-Amchitka, Alaska,BV

233

Procurement Services Involvement with Contracts  

E-Print Network [OSTI]

Diligence and/or pre-qualification information to make sure vendors are a viable source. (Alumnus, disadvantaged vendor programs, etc.) Facilitation Services, sustainability information on equipment

Huang, Jianyu

234

Synthesis and Application of an Environmentally Insensitive Cy3-Based Arsenical Fluorescent Probe to Identify Adaptive Microbial Responses Involving Proximal Dithiol Oxidation  

SciTech Connect (OSTI)

Reversible disulfide oxidation between proximal cysteines in proteins represents a common regulatory control mechanism to modulate flux through metabolic pathways in response to changing environmental conditions. To enable in vivo measurements of cellular redox changes linked to disulfide bond formation, we have synthesized a cell-permeable monosubstituted cyanine dye derivatized with arsenic (i.e., TRAP_Cy3) to trap and visualize dithiols in cytosolic proteins. Alkylation of reactive thiols prior to displacement of the bound TRAP-Cy3 by ethanedithiol permits facile protein capture and mass spectrometric identification of proximal reduced dithiols to the exclusion of individual cysteines. Applying TRAP_Cy3 to evaluate cellular responses to increases in oxygen and light levels in the photosynthetic microbe Synechococcus sp. PCC 7002, we observe large decreases in the abundance of reduced dithiols in cellular proteins, which suggest redox-dependent mechanisms involving the oxidation of proximal disulfides. Under these same growth conditions that result in the oxidation of proximal thiols, there is a reduction in the abundance of post-translational oxidative modifications involving nitrotyrosine and methionine sulfoxide formation. These results suggest that the redox status of proximal cysteines respond to environmental conditions, acting to regulate metabolic flux and minimize the formation of reactive oxygen species to decrease oxidative protein damage.

Fu, Na; Su, Dian; Cort, John R.; Chen, Baowei; Xiong, Yijia; Qian, Weijun; Konopka, Allan; Bigelow, Diana J.; Squier, Thomas C.

2013-03-06T23:59:59.000Z

235

Early Brain Response to Low-Dose Radiation Exposure Involves Molecular Networks and Pathways Associated with Cognitive Functions, Advanced Aging and Alzheimer's Disease  

SciTech Connect (OSTI)

Understanding the cognitive and behavioral consequences of brain exposures to low-dose ionizing radiation has broad relevance for health risks from medical radiation diagnostic procedures, radiotherapy, environmental nuclear contamination, as well as earth orbit and space missions. Analyses of transcriptome profiles of murine brain tissue after whole-body radiation showed that low-dose exposures (10 cGy) induced genes not affected by high dose (2 Gy), and low-dose genes were associated with unique pathways and functions. The low-dose response had two major components: pathways that are consistently seen across tissues, and pathways that were brain tissue specific. Low-dose genes clustered into a saturated network (p < 10{sup -53}) containing mostly down-regulated genes involving ion channels, long-term potentiation and depression, vascular damage, etc. We identified 9 neural signaling pathways that showed a high degree of concordance in their transcriptional response in mouse brain tissue after low-dose radiation, in the aging human brain (unirradiated), and in brain tissue from patients with Alzheimer's disease. Mice exposed to high-dose radiation did not show these effects and associations. Our findings indicate that the molecular response of the mouse brain within a few hours after low-dose irradiation involves the down-regulation of neural pathways associated with cognitive dysfunctions that are also down regulated in normal human aging and Alzheimer's disease.

Lowe, Xiu R; Bhattacharya, Sanchita; Marchetti, Francesco; Wyrobek, Andrew J.

2008-06-06T23:59:59.000Z

236

Derivation of the Blackbody Radiation Spectrum from a Natural Maximum-Entropy Principle Involving Casimir Energies and Zero-Point Radiation  

E-Print Network [OSTI]

By numerical calculation, the Planck spectrum with zero-point radiation is shown to satisfy a natural maximum-entropy principle whereas alternative choices of spectra do not. Specifically, if we consider a set of conducting-walled boxes, each with a partition placed at a different location in the box, so that across the collection of boxes the partitions are uniformly spaced across the volume, then the Planck spectrum correspond to that spectrum of random radiation (having constant energy kT per normal mode at low frequencies and zero-point energy (1/2)hw per normal mode at high frequencies) which gives maximum uniformity across the collection of boxes for the radiation energy per box. The analysis involves Casimir energies and zero-point radiation which do not usually appear in thermodynamic analyses. For simplicity, the analysis is presented for waves in one space dimension.

Timothy H. Boyer

2002-10-30T23:59:59.000Z

237

Dosimetric Comparison of Involved-Field Three-Dimensional Conformal Photon Radiotherapy and Breast-Sparing Proton Therapy for the Treatment of Hodgkin's Lymphoma in Female Pediatric Patients  

SciTech Connect (OSTI)

Purpose: To assess the potential reduction in breast dose for young girls with Hodgkin's lymphoma (HL) treated with breast-sparing proton therapy (BS-PT) as compared with three-dimensional conformal involved-field photon radiotherapy (3D-CRT). Methods and Materials: The Clarian Health Cancer Registry was queried for female pediatric patients with the diagnosis of HL who received radiotherapy at the Indiana University Simon Cancer Center during 2006-2009. The original CT simulation images were obtained, and 3D-CRT and BS-PT plans delivering 21 Gy or cobalt gray equivalent (CGE) in 14 fractions were created for each patient. Dose-volume histogram data were collected for both 3D-CRT and BS-PT plans and compared by paired t test for correlated samples. Results: The cancer registry provided 10 female patients with Ann Arbor Stage II HL, aged 10-18 years at the time of treatment. Both mean and maximum breast dose were significantly less with BS-PT compared with 3D-CRT: 0.95 CGE vs. 4.70 Gy (p < 0.001) and 21.07 CGE vs. 23.11 Gy (p < 0.001), respectively. The volume of breast receiving 1.0 Gy/CGE and 5.0 Gy/CGE was also significantly less with BS-PT, 194 cm{sup 3} and 93 cm{sup 3}, respectively, compared with 790 cm{sup 3} and 360 cm{sup 3} with 3D-CRT (p = 0.009, 0.013). Conclusion: Breast-sparing proton therapy has the potential to reduce unnecessary breast dose in young girls with HL by as much as 80% relative to involved-field 3D-CRT.

Andolino, David L., E-mail: dandolin@iupui.edu [Department of Radiation Oncology, Indiana University School of Medicine, Bloomington, IN (United States); Hoene, Ted [Midwest Proton Radiotherapy Institute, Bloomington, IN (United States); Xiao, Lu [Department of Radiation Oncology, Indiana University School of Medicine, Bloomington, IN (United States); Buchsbaum, Jeffrey; Chang, Andrew L. [Department of Radiation Oncology, Indiana University School of Medicine, Bloomington, IN (United States); Midwest Proton Radiotherapy Institute, Bloomington, IN (United States)

2011-11-15T23:59:59.000Z

238

Disturbance of DKK1 level is partly involved in survival of lung cancer cells via regulation of ROMO1 and ?-radiation sensitivity  

SciTech Connect (OSTI)

Highlights: DKK1 was expressed differently among non-small-cell lung cancer cell lines. DKK1 negatively regulated ROMO1 gene expression. Disturbance of DKK1 level induced the imbalance of cellular ROS. DKK1/ROMO1-induced ROS imbalance is involved in cell survival in NSCLC. -- Abstract: Dickkopf1 (DKK1), a secreted protein involved in embryonic development, is a potent inhibitor of the Wnt signaling pathway and has been postulated to be a tumor suppressor or tumor promoter depending on the tumor type. In this study, we showed that DKK1 was expressed differently among non-small-cell lung cancer cell lines. The DKK1 expression level was much higher in A549 cells than in H460 cells. We revealed that blockage of DKK1 expression by silencing RNA in A549 cells caused up-regulation of intracellular reactive oxygen species (ROS) modulator (ROMO1) protein, followed by partial cell death, cell growth inhibition, and loss of epithelialmesenchymal transition property caused by ROS, and it also increased ?-radiation sensitivity. DKK1 overexpression in H460 significantly inhibited cell survival with the decrease of ROMO1 level, which induced the decrease of cellular ROS. Thereafter, exogenous N-acetylcysteine, an antioxidant, or hydrogen peroxide, a pro-oxidant, partially rescued cells from death and growth inhibition. In each cell line, both overexpression and blockage of DKK1 not only elevated p-RB activation, which led to cell growth arrest, but also inactivated AKT/NF-kB, which increased radiation sensitivity and inhibited cell growth. This study is the first to demonstrate that strict modulation of DKK1 expression in different cell types partially maintains cell survival via tight regulation of the ROS-producing ROMO1 and radiation resistance.

Kim, In Gyu, E-mail: igkim@kaeri.re.kr [Department of Radiation Biology, Environmental Radiation Research Group, Korea Atomic Energy Research Institute, P.O. Box 105, Yuseong, Daejeon 305-600 (Korea, Republic of); Department of Radiation Biotechnology and Applied Radioisotope, University of Science and Technology (UST), 989-111 Daedeok-daero, Yuseong-gu, Daejeon 305-353 (Korea, Republic of); Kim, Seo Yoen [Department of Radiation Biology, Environmental Radiation Research Group, Korea Atomic Energy Research Institute, P.O. Box 105, Yuseong, Daejeon 305-600 (Korea, Republic of) [Department of Radiation Biology, Environmental Radiation Research Group, Korea Atomic Energy Research Institute, P.O. Box 105, Yuseong, Daejeon 305-600 (Korea, Republic of); Biomedical Translational Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Yuseong-gu, Daejeon 305-806 (Korea, Republic of); Kim, Hyun A; Kim, Jeong Yul [Department of Radiation Biology, Environmental Radiation Research Group, Korea Atomic Energy Research Institute, P.O. Box 105, Yuseong, Daejeon 305-600 (Korea, Republic of)] [Department of Radiation Biology, Environmental Radiation Research Group, Korea Atomic Energy Research Institute, P.O. Box 105, Yuseong, Daejeon 305-600 (Korea, Republic of); Lee, Jae Ha; Choi, Soo Im [Department of Radiation Biology, Environmental Radiation Research Group, Korea Atomic Energy Research Institute, P.O. Box 105, Yuseong, Daejeon 305-600 (Korea, Republic of) [Department of Radiation Biology, Environmental Radiation Research Group, Korea Atomic Energy Research Institute, P.O. Box 105, Yuseong, Daejeon 305-600 (Korea, Republic of); Department of Radiation Biotechnology and Applied Radioisotope, University of Science and Technology (UST), 989-111 Daedeok-daero, Yuseong-gu, Daejeon 305-353 (Korea, Republic of); Han, Jeong Ran; Kim, Kug Chan [Department of Radiation Biology, Environmental Radiation Research Group, Korea Atomic Energy Research Institute, P.O. Box 105, Yuseong, Daejeon 305-600 (Korea, Republic of)] [Department of Radiation Biology, Environmental Radiation Research Group, Korea Atomic Energy Research Institute, P.O. Box 105, Yuseong, Daejeon 305-600 (Korea, Republic of); Cho, Eun Wie [Biomedical Translational Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Yuseong-gu, Daejeon 305-806 (Korea, Republic of)] [Biomedical Translational Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Yuseong-gu, Daejeon 305-806 (Korea, Republic of)

2014-01-03T23:59:59.000Z

239

An evaluation of the TSE MR sequence for time efficient data acquisition in polymer gel dosimetry of applications involving high doses and steep dose gradients  

SciTech Connect (OSTI)

The use of magnetic resonance imaging as a readout method for polymer gel dosimetry commonly involves long imaging sessions, particularly when high spatial resolution is required in all three dimensions, for the investigation of dose distributions with steep dose gradients and stringent dose delivery specifications. In this work, a volume selective turbo spin echo (TSE) pulse sequence is compared to the established Carr-Purcell-Meiboom-Gill (CPMG) multiecho acquisition with regard to providing accurate dosimetric results in significantly reduced imaging times. Polyethylene glycol diacrylate based (PABIG) gels were irradiated and subsequently scanned to obtain R2 relaxation rate measurements, using a CPMG multiecho sequence and a dual echo TSE utilizing an acceleration (turbo) factor of 64. R2 values, plotted against corresponding Monte Carlo dose calculations, provided calibration data of PABIG gels dose response over a wide dose range. A linear R2 versus dose relationship was demonstrated for both sequences with TSE results presenting reduced dose sensitivity. Although TSE data were found to deviate from linearity at lower doses compared to CPMG data, a relatively wide dynamic dose range of response extending up to approximately 100 Gy was observed for both sequences. The TSE and CPMG sequences were evaluated with a brachytherapy irradiation using a high dose rate {sup 192}Ir source and a gamma knife stereotactic radiosurgery irradiation with a single 4 mm collimator helmet shot. Dosimetric results obtained with the TSE and CPMG are shown to compare equally well with the expected dose distributions for these irradiations. The 60-fold scan time reduction achieved with TSE implies that this sequence could prove to be a useful tool for the introduction of polymer gel dosimetry in clinical radiation therapy applications involving high doses and steep dose gradients.

Baras, P.; Seimenis, I.; Sandilos, P.; Vlahos, L.; Bieganski, T.; Georgiou, E.; Pantelis, E.; Papagiannis, P.; Sakelliou, L. [Philips Hellas Medical Systems, 44 Kifissias Ave., Maroussi 151 25, Athens (Greece); Department of Radiology, Medical School, University of Athens, Areteion Hospital, 76 Vas. Sofias Ave., 115 28 Athens (Greece) and Medical Physics Department, Hygeia Hospital, Kiffisias Avenue, 24 Erythrou Stavrou, Marousi, 151 23, Athens (Greece); Department of Radiology, Mother's Memorial Hospital, Rzgowska 281/289, 93-388, Lodz (Poland); Medical Physics Department, University of Athens, 75 Mikras Asias, 115 27 Athens (Greece); Nuclear and Particle Physics Section, Physics Department, University of Athens, Panepistimioupolis, Ilisia, 157 71 Athens (Greece)

2005-11-15T23:59:59.000Z

240

Epigenetic involvement of Alien/ESET complex in thyroid hormone-mediated repression of E2F1 gene expression and cell proliferation  

SciTech Connect (OSTI)

Highlights: Black-Right-Pointing-Pointer Corepressor Alien interacts with histone methyltransferase ESET in vivo. Black-Right-Pointing-Pointer Alien/ESET complex is recruited to nTRE of T3-responsive gene by liganded TR{beta}1. Black-Right-Pointing-Pointer ESET-mediated H3K9 methylation is required for liganded TR{beta}1-repressed transcription. Black-Right-Pointing-Pointer ESET is involved in T3-repressed G1/S phase transition and proliferation. -- Abstract: The ligand-bound thyroid hormone receptor (TR) is known to repress via a negative TRE (nTRE) the expression of E2F1, a key transcription factor that controls the G1/S phase transition. Alien has been identified as a novel interacting factor of E2F1 and acts as a corepressor of E2F1. The detailed molecular mechanism by which Alien inhibits E2F1 gene expression remains unclear. Here, we report that the histone H3 lysine 9 (H3K9) methyltransferase (HMT) ESET is an integral component of the corepressor Alien complex and the Alien/ESET complex is recruited to both sites, the E2F1 and the nTRE site of the E2F1 gene while the recruitment to the negative thyroid hormone response element (nTRE) is induced by the ligand-bound TR{beta}1 within the E2F1 gene promoter. We show that, overexpression of ESET promotes, whereas knockdown of ESET releases, the inhibition of TR{beta}1-regulated gene transcription upon T3 stimulation; and H3K9 methylation is required for TR{beta}1-repressed transcription. Furthermore, depletion of ESET impairs thyroid hormone-repressed proliferation as well as the G1/S transition of the cell cycle. Taken together, our data indicate that ESET is involved in TR{beta}1-mediated transcription repression and provide a molecular basis of thyroid hormone-induced repression of proliferation.

Hong, Wei, E-mail: hongwei@tijmu.edu.cn [Department of Immunology, Tianjin Medical University, 300070 Tianjin (China) [Department of Immunology, Tianjin Medical University, 300070 Tianjin (China); College of Basic Medicine, Tianjin Medical University, 300070 Tianjin (China); Li, Jinru; Wang, Bo [College of Basic Medicine, Tianjin Medical University, 300070 Tianjin (China)] [College of Basic Medicine, Tianjin Medical University, 300070 Tianjin (China); Chen, Linfeng [Department of Medical Oncology, Harvard Medical School, Dana Farber Cancer Institute, Boston, 02115 MA (United States)] [Department of Medical Oncology, Harvard Medical School, Dana Farber Cancer Institute, Boston, 02115 MA (United States); Niu, Wenyan; Yao, Zhi [Department of Immunology, Tianjin Medical University, 300070 Tianjin (China)] [Department of Immunology, Tianjin Medical University, 300070 Tianjin (China); Baniahmad, Aria, E-mail: aban@mti.uni-jena.de [Institute for Human Genetics, Jena University Hospital, 07740 Jena (Germany)] [Institute for Human Genetics, Jena University Hospital, 07740 Jena (Germany)

2011-12-02T23:59:59.000Z

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241

Consolidative Involved-Node Proton Therapy for Stage IA-IIIB Mediastinal Hodgkin Lymphoma: Preliminary Dosimetric Outcomes From a Phase II Study  

SciTech Connect (OSTI)

Purpose: To compare the dose reduction to organs at risk (OARs) with proton therapy (PT) versus three-dimensional conformal radiotherapy (3D-CRT) and intensity-modulated radiotherapy (IMRT) in patients with mediastinal Hodgkin lymphoma (HL) enrolled on a Phase II study of involved-node radiotherapy (INRT). Methods and Materials: Between June 2009 and October 2010, 10 patients were enrolled on a University of Florida institutional review board-approved protocol for de novo 'classical' Stage IA-IIIB HL with mediastinal (bulky or nonbulky) involvement after chemotherapy. INRT was planned per European Organization for Research and Treatment of Cancer guidelines. Three separate optimized plans were developed for each patient: 3D-CRT, IMRT, and PT. The primary end point was a 50% reduction in the body V4 with PT compared with 3D-CRT or IMRT. Results: The median relative reduction with PT in the primary end point, body V4, was 51% compared with 3D-CRT (p = 0.0098) and 59% compared with IMRT (p = 0.0020), thus all patients were offered treatment with PT. PT provided the lowest mean dose to the heart, lungs, and breasts for all 10 patients compared with either 3D-CRT or IMRT. The median difference in the OAR mean dose reduction with PT compared with 3D-CRT were 10.4 Gy/CGE for heart; 5.5 Gy/CGE for lung; 0.9 Gy/CGE for breast; 8.3 Gy/CGE for esophagus; and 4.1 Gy/CGE for thyroid. The median differences for mean OAR dose reduction for PT compared with IMRT were 4.3 Gy/CGE for heart, 3.1 Gy/CGE for lung, 1.4 Gy/CGE for breast, 2.8 Gy/CGE for esophagus, and 2.7 Gy/CGE for thyroid. Conclusions: All 10 patients benefitted from dose reductions to OARs with PT compared with either 3D-CRT or IMRT. It is anticipated that these reductions in dose to OAR will translate into lower rates of late complications, but long-term follow-up on this Phase II INRT study is needed.

Hoppe, Bradford S., E-mail: bhoppe@floridaproton.org [University of Florida Proton Therapy Institute, Jacksonville, FL (United States); Flampouri, Stella; Su Zhong; Morris, Christopher G. [University of Florida Proton Therapy Institute, Jacksonville, FL (United States); Latif, Naeem [University of Florida Hematology/Oncology, Jacksonville, FL (United States); Dang, Nam H.; Lynch, James [University of Florida Hematology/Oncology, Gainesville, FL (United States); Li Zuofeng; Mendenhall, Nancy P. [University of Florida Proton Therapy Institute, Jacksonville, FL (United States)

2012-05-01T23:59:59.000Z

242

Landscaping encompasses all the features that add beauty and utility to your property beyond the walls of your home. Plants are one primary element of landscape design. Good design with plants involves an  

E-Print Network [OSTI]

the walls of your home. Plants are one primary element of landscape design. Good design with plants involves to be "usefully hardy" in your area. Though a plant may grow fairly well, if it is sufficiently injured by cold

New Hampshire, University of

243

Bixin regulates mRNA expression involved in adipogenesis and enhances insulin sensitivity in 3T3-L1 adipocytes through PPAR{gamma} activation  

SciTech Connect (OSTI)

Insulin resistance is partly due to suppression of insulin-induced glucose uptake into adipocytes. The uptake is dependent on adipocyte differentiation, which is controlled at mRNA transcription level. The peroxisome proliferator-activated receptor (PPAR), a ligand-regulated nuclear receptor, is involved in the differentiation. Many food-derived compounds serve as ligands to activate or inactivate PPAR. In this study, we demonstrated that bixin and norbixin (annatto extracts) activate PPAR{gamma} by luciferase reporter assay using GAL4-PPAR chimera proteins. To examine the effects of bixin on adipocytes, 3T3-L1 adipocytes were treated with bixin or norbixin. The treatment induced mRNA expression of PPAR{gamma} target genes such as adipocyte-specific fatty acid-binding protein (aP2), lipoprotein lipase (LPL), and adiponectin in differentiated 3T3-L1 adipocytes and enhanced insulin-dependent glucose uptake. The observations indicate that bixin acts as an agonist of PPAR{gamma} and enhances insulin sensitivity in 3T3-L1 adipocytes, suggesting that bixin is a valuable food-derived compound as a PPAR ligand to regulate lipid metabolism and to ameliorate metabolic syndrome.

Takahashi, Nobuyuki; Goto, Tsuyoshi; Taimatsu, Aki; Egawa, Kahori; Katoh, Sota; Kusudo, Tatsuya; Sakamoto, Tomoya; Ohyane, Chie; Lee, Joo-Young; Kim, Young-il; Uemura, Taku; Hirai, Shizuka [Laboratory of Molecular Function of Food, Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Uji 611-0011 (Japan)] [Laboratory of Molecular Function of Food, Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Uji 611-0011 (Japan); Kawada, Teruo, E-mail: fat@kais.kyoto-u.ac.jp [Laboratory of Molecular Function of Food, Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Uji 611-0011 (Japan)] [Laboratory of Molecular Function of Food, Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Uji 611-0011 (Japan)

2009-12-25T23:59:59.000Z

244

Suggestive Evidence for the Involvement of the Second Calcium and Surface Loop in Interfacial Binding: Monoclinci and Trigonal Crystal Structures of a Quadruple Mutant of Phospholipase A2  

SciTech Connect (OSTI)

The crystal structures of the monoclinic and trigonal forms of the quadruple mutant K53,56,120,121M of recombinant bovine pancreatic phospholipase A{sub 2} (PLA{sub 2}) have been solved and refined at 1.9 and 1.1 Angstroms resolution, respectively. Interestingly, the monoclinic form reveals the presence of the second calcium ion. Furthermore, the surface-loop residues are ordered and the conformation of residues 62-66 is similar to that observed in other structures containing the second calcium ion. On the other hand, in the trigonal form the surface loop is disordered and the second calcium is absent. Docking studies suggest that the second calcium and residues Lys62 and Asp66 from the surface loop could be involved in the interaction with the polar head group of the membrane phospholipid. It is hypothesized that the two structures of the quadruple mutant, monoclinic and trigonal, represent the conformations of PLA2 at the lipid interface and in solution, respectively. A docked structure with a phospholipid molecule and with a transition-state analogue bound, one at the active site coordinating to the catalytic calcium and the other at the second calcium site, but both at the i-face, is presented.

Sekar,K.; Yogavel, M.; Kanaujia, S.; Sharma, A.; Velmurugan, D.; Poi, M.; Dauter, Z.; Tsai, M.

2006-01-01T23:59:59.000Z

245

t(8; 14) chromosome translocation of the Burkitt lymphoma cell line Daudi occurred during immunoglobulin gene rearrangement and involved the heavy chain diversity region  

SciTech Connect (OSTI)

Recent molecular analyses of Burkitt lymphomas carrying the t(8;14) chromosome translocation have indicated that a dichotomy exists regarding the molecular mechanisms by which the translocations occur. Most sporadic Burkitt tumors carry translocations that apparently arise due to mistakes in the immunoglobulin isotype-switching process. In contrast, there is evidence that the translocations of most endemic Burkitt lymphomas occur as a consequence of aberrant V-D-J recombination of variable, diversity, and joining gene segments, catalyzed by the recombinase enzymes. This phenomenon was first noted in follicular lymphomas and chronic lymphocytic leukemias of the B-cell lineage and has been described in T-cell malignancies as well. In each of these cases, analysis of the nucleotide sequence at chromosome breakpoints demonstrated the involvement of immunoglobulin heavy chain J/sub H/ or T-cell-receptor ..cap alpha..-chain J..cap alpha.. gene segments in the translocation. The authors now have cloned and sequenced both the 8q- and 14q+ translocation breakpoints deriving from the t(8;14) translocation of the endemic Burkitt lymphoma line Daudi. The data show that the translocation resulted from a reciprocal exchange between the D/sub H/ region on chromosome 14 and sequences far 5' of the MYC protooncogene on chromosome 8. Features of the nucleotide sequences surrounding the breakpoint further implicate the V-D-J joining machinery in the genesis of chromosome translocation in endemic Burkitt lymphomas and, more generally, in other lymphoid malignancies as well.

Haluska, F.G.; Tsujimoto, Y.; Croce, C.M.

1987-10-01T23:59:59.000Z

246

Nanowires, Capacitors, and Other Novel Outer-Surface Components Involved in Electron Transfer to Fe(III) Oxides in Geobacter Species  

SciTech Connect (OSTI)

The overall goal of this project was to better understand the mechanisms by which Geobacter species transfer electrons outside the cell onto Fe(III) oxides. The rationale for this study was that Geobacter species are often the predominant microorganisms involved in in situ uranium bioremediation and the growth and activity of the Geobacter species during bioremediation is primarily supported by electron transfer to Fe(III) oxides. These studies greatly expanded the understanding of electron transfer to Fe(III). Novel concepts developed included the potential role of microbial nanowires for long range electron transfer in Geobacter species and the importance of extracytoplasmic cytochromes functioning as capacitors to permit continued electron transfer during the hunt for Fe(III) oxide. Furthermore, these studies provided target sequences that were then used in other studies to tract the activity of Geobacter species in the subsurface through monitoring the abundance of gene transcripts of the target genes. A brief summary of the major accomplishments of the project is provided.

Lovley, Derek, R.

2008-12-22T23:59:59.000Z

247

Cytotoxicity of synthetic cannabinoids on primary neuronal cells of the forebrain: the involvement of cannabinoid CB{sub 1} receptors and apoptotic cell death  

SciTech Connect (OSTI)

The abuse of herbal products containing synthetic cannabinoids has become an issue of public concern. The purpose of this paper was to evaluate the acute cytotoxicity of synthetic cannabinoids on mouse brain neuronal cells. Cytotoxicity induced by synthetic cannabinoid (CP-55,940, CP-47,497, CP-47,497-C8, HU-210, JWH-018, JWH-210, AM-2201, and MAM-2201) was examined using forebrain neuronal cultures. These synthetic cannabinoids induced cytotoxicity in the forebrain cultures in a concentration-dependent manner. The cytotoxicity was suppressed by preincubation with the selective CB{sub 1} receptor antagonist AM251, but not with the selective CB{sub 2} receptor antagonist AM630. Furthermore, annexin-V-positive cells were found among the treated forebrain cells. Synthetic cannabinoid treatment induced the activation of caspase-3, and preincubation with a caspase-3 inhibitor significantly suppressed the cytotoxicity. These synthetic cannabinoids induced apoptosis through a caspase-3-dependent mechanism in the forebrain cultures. Our results indicate that the cytotoxicity of synthetic cannabinoids towards primary neuronal cells is mediated by the CB{sub 1} receptor, but not by the CB{sub 2} receptor, and further suggest that caspase cascades may play an important role in the apoptosis induced by these synthetic cannabinoids. In conclusion, excessive synthetic cannabinoid abuse may present a serious acute health concern due to neuronal damage or deficits in the brain. - Highlights: Synthetic cannabinoids (classical cannabinoids, non-classical cannabinoids, and aminoalkylindole derivatives) induce cytotoxicity in mouse forebrain cultures. Synthetic cannabinoid-induced cytotoxicity towards forebrain cultures is mediated by the CB{sub 1} receptor, but not by the CB{sub 2} receptor, and involves caspase-dependent apoptosis. A high concentration of synthetic cannabinoids may be toxic to neuronal cells that express CB{sub 1} receptors.

Tomiyama, Ken-ichi; Funada, Masahiko, E-mail: mfunada@ncnp.go.jp

2014-01-01T23:59:59.000Z

248

Impaired NFAT and NF?B activation are involved in suppression of CD40 ligand expression by ?{sup 9}-tetrahydrocannabinol in human CD4{sup +} T cells  

SciTech Connect (OSTI)

We have previously reported that ?{sup 9}-tetrahydrocannabinol (?{sup 9}-THC), the main psychoactive cannabinoid in marijuana, suppresses CD40 ligand (CD40L) expression by activated mouse CD4{sup +} T cells. CD40L is involved in pathogenesis of many autoimmune and inflammatory diseases. In the present study, we investigated the molecular mechanism of ?{sup 9}-THC-mediated suppression of CD40L expression using peripheral blood human T cells. Pretreatment with ?{sup 9}-THC attenuated CD40L expression in human CD4{sup +} T cells activated by anti-CD3/CD28 at both the protein and mRNA level, as determined by flow cytometry and quantitative real-time PCR, respectively. Electrophoretic mobility shift assays revealed that ?{sup 9}-THC suppressed the DNA-binding activity of both NFAT and NF?B to their respective response elements within the CD40L promoter. An assessment of the effect of ?{sup 9}-THC on proximal T cell-receptor (TCR) signaling induced by anti-CD3/CD28 showed significant impairment in the rise of intracellular calcium, but no significant effect on the phosphorylation of ZAP70, PLC?1/2, Akt, and GSK3?. Collectively, these findings identify perturbation of the calcium-NFAT and NF?B signaling cascade as a key mechanistic event by which ?{sup 9}-THC suppresses human T cell function. - Highlights: ?{sup 9}-THC attenuated CD40L expression in activated human CD4+ T cells. ?{sup 9}-THC suppressed DNA-binding activity of NFAT and NF?B. ?{sup 9}-THC impaired elevation of intracellular Ca2+. ?{sup 9}-THC did not affect phosphorylation of ZAP70, PLC?1/2, Akt, and GSK3?.

Ngaotepprutaram, Thitirat [Department of Pharmacology and Toxicology, Michigan State University (United States); Center for Integrative Toxicology, Michigan State University (United States); Kaplan, Barbara L.F. [Department of Pharmacology and Toxicology, Michigan State University (United States); Center for Integrative Toxicology, Michigan State University (United States); Neuroscience Program, Michigan State University (United States); Kaminski, Norbert E., E-mail: kamins11@msu.edu [Department of Pharmacology and Toxicology, Michigan State University (United States); Center for Integrative Toxicology, Michigan State University (United States)

2013-11-15T23:59:59.000Z

249

Losartan attenuates chronic cigarette smoke exposure-induced pulmonary arterial hypertension in rats: Possible involvement of angiotensin-converting enzyme-2  

SciTech Connect (OSTI)

Chronic cigarette smoking induces pulmonary arterial hypertension (PAH) by largely unknown mechanisms. Renin-angiotensin system (RAS) is known to function in the development of PAH. Losartan, a specific angiotensin II receptor antagonist, is a well-known antihypertensive drug with a potential role in regulating angiotensin-converting enzyme-2 (ACE2), a recently found regulator of RAS. To determine the effect of losartan on smoke-induced PAH and its possible mechanism, rats were daily exposed to cigarette smoke for 6 months in the absence and in the presence of losartan. Elevated right ventricular systolic pressure (RVSP), thickened wall of pulmonary arteries with apparent medial hypertrophy along with increased angiotensin II (Ang II) and decreased ACE2 levels were observed in smoke-exposed-only rats. Losartan administration ameliorated pulmonary vascular remodeling, inhibited the smoke-induced RVSP and Ang II elevation and partially reversed the ACE2 decrease in rat lungs. In cultured primary pulmonary artery smooth muscle cells (PASMCs) from 3- and 6-month smoke-exposed rats, ACE2 levels were significantly lower than in those from the control rats. Moreover, PASMCs from 6-month exposed rats proliferated more rapidly than those from 3-month exposed or control rats, and cells grew even more rapidly in the presence of DX600, an ACE2 inhibitor. Consistent with the in vivo study, in vitro losartan pretreatment also inhibited cigarette smoke extract (CSE)-induced cell proliferation and ACE2 reduction in rat PASMCs. The results suggest that losartan may be therapeutically useful in the chronic smoking-induced pulmonary vascular remodeling and PAH and ACE2 may be involved as part of its mechanism. Our study might provide insight into the development of new therapeutic interventions for PAH smokers.

Han Suxia; He Guangming; Wang Tao; Chen Lei; Ning Yunye; Luo Feng; An Jin; Yang Ting; Dong Jiajia; Liao Zenglin; Xu Dan [Division of Pulmonary Diseases, State Key Laboratory of Biotherapy of China, and Department of Respiratory Medicine, West China Hospital of Sichuan University, Chengdu, Sichuan 610041 (China); Wen Fuqiang, E-mail: wenfuqiang.scu@gmail.co [Division of Pulmonary Diseases, State Key Laboratory of Biotherapy of China, and Department of Respiratory Medicine, West China Hospital of Sichuan University, Chengdu, Sichuan 610041 (China)

2010-05-15T23:59:59.000Z

250

Epithelialmesenchymal transition during oncogenic transformation induced by hexavalent chromium involves reactive oxygen species-dependent mechanism in lung epithelial cells  

SciTech Connect (OSTI)

Hexavalent chromium [Cr(VI)] is an important human carcinogen associated with pulmonary diseases and lung cancer. Exposure to Cr(VI) induces DNA damage, cell morphological change and malignant transformation in human lung epithelial cells. Despite extensive studies, the molecular mechanisms remain elusive, it is also not known if Cr(VI)-induced transformation might accompany with invasive properties to facilitate metastasis. We aimed to study Cr(VI)-induced epithelialmesenchymal transition (EMT) and invasion during oncogenic transformation in lung epithelial cells. The results showed that Cr(VI) at low doses represses E-cadherin mRNA and protein expression, enhances mesenchymal marker vimentin expression and transforms the epithelial cell into fibroblastoid morphology. Cr(VI) also increases cell invasion and promotes colony formation. Further studies indicated that Cr(VI) uses multiple mechanisms to repress E-cadherin expression, including activation of E-cadherin repressors such as Slug, ZEB1, KLF8 and enhancement the binding of HDAC1 in E-cadherin gene promoter, but DNA methylation is not responsible for the loss of E-cadherin. Catalase reduces Cr(VI)-induced E-cadherin and vimentin protein expression, attenuates cell invasion in matrigel and colony formation on soft agar. These results demonstrate that exposure to a common human carcinogen, Cr(VI), induces EMT and invasion during oncogenic transformation in lung epithelial cells and implicate in cancer metastasis and prevention. - Graphical abstract: Epithelialmesenchymal transition during oncogenic transformation induced by hexavalent chromium involves reactive oxygen species-dependent mechanisms in lung epithelial cells. - Highlights: We study if Cr(VI) might induce EMT and invasion in epithelial cells. Cr(VI) induces EMT by altering E-cadherin and vimentin expression. It also increases cell invasion and promotes oncogenic transformation. Catalase reduces Cr(VI)-induced EMT, invasion and transformation.

Ding, Song-Ze, E-mail: dingsongze@hotmail.com [Department of Internal Medicine, Henan Provincial Peoples Hospital, Zhengzhou University, Wei-Wu Road, Zhengzhou, Henan 450000 (China); Graduate Center for Toxicology, College of Medicine, University of Kentucky, Lexington, KY 40536 (United States); Yang, Yu-Xiu; Li, Xiu-Ling [Department of Internal Medicine, Henan Provincial Peoples Hospital, Zhengzhou University, Wei-Wu Road, Zhengzhou, Henan 450000 (China); Michelli-Rivera, Audrey [Graduate Center for Toxicology, College of Medicine, University of Kentucky, Lexington, KY 40536 (United States); Han, Shuang-Yin [Department of Internal Medicine, Henan Provincial Peoples Hospital, Zhengzhou University, Wei-Wu Road, Zhengzhou, Henan 450000 (China); Wang, Lei; Pratheeshkumar, Poyil; Wang, Xin; Lu, Jian; Yin, Yuan-Qin; Budhraja, Amit; Hitron, Andrew J. [Graduate Center for Toxicology, College of Medicine, University of Kentucky, Lexington, KY 40536 (United States)

2013-05-15T23:59:59.000Z

251

Twice-Weekly Hypofractionated Intensity-Modulated Radiotherapy for Localized Prostate Cancer With Low-Risk Nodal Involvement: Toxicity and Outcome From a Dose Escalation Pilot Study  

SciTech Connect (OSTI)

Purpose: To evaluate the toxicity and preliminary outcome of patients with localized prostate cancer treated with twice-weekly hypofractionated intensity-modulated radiotherapy (IMRT). Methods and Materials: Between 2003 and 2006, 82 prostate cancer patients with a nodal involvement risk {<=}20% (Roach index) have been treated to the prostate with or without seminal vesicles with 56 Gy (4 Gy/fraction twice weekly) and an overall treatment time of 6.5 weeks. Acute and late genitourinary (GU) and gastrointestinal (GI) toxicities were scored according to the Radiation Therapy Oncology Group (RTOG) grading system. Median follow-up was 48 months (range, 9-67 months). Results: All patients completed the treatment without interruptions. No patient presented with Grade {>=}3 acute GU or GI toxicity. Of the patients, 4% presented with Grade 2 GU or GI persistent acute toxicity 6 weeks after treatment completion. The estimated 4-year probability of Grade {>=}2 late GU and GI toxicity-free survival were 94.2% {+-} 2.9% and 96.1% {+-} 2.2%, respectively. One patient presented with Grade 3 GI and another patient with Grade 4 GU late toxicity, which were transitory in both cases. The 4-year actuarial biochemical relapse-free survival was 91.3% {+-} 5.9%, 76.4% {+-} 8.8%, and 77.5% {+-} 8.9% for low-, intermediate-, and high-risk groups, respectively. Conclusions: In patients with localized prostate cancer, acute and late toxicity were minimal after dose-escalation administering twice-weekly 4 Gy to a total dose of 56 Gy, with IMRT. Further prospective trials are warranted to further assess the best fractionation schemes for these patients.

Zilli, Thomas, E-mail: thomaszilli@inwind.it [Service de Radio-oncologie, Hopitaux Universitaires de Geneve, Geneva (Switzerland); Jorcano, Sandra [Servei de Radio-oncologia, Institut Oncologic Teknon, Barcelona (Spain); Rouzaud, Michel; Dipasquale, Giovanna; Nouet, Philippe [Service de Radio-oncologie, Hopitaux Universitaires de Geneve, Geneva (Switzerland); Toscas, Jose Ignacio [Servei de Radio-oncologia, Institut Oncologic Teknon, Barcelona (Spain); Casanova, Nathalie; Wang, Hui [Service de Radio-oncologie, Hopitaux Universitaires de Geneve, Geneva (Switzerland); Escude, Lluis; Molla, Meritxell; Linero, Dolors [Servei de Radio-oncologia, Institut Oncologic Teknon, Barcelona (Spain); Weber, Damien C. [Service de Radio-oncologie, Hopitaux Universitaires de Geneve, Geneva (Switzerland); Miralbell, Raymond [Service de Radio-oncologie, Hopitaux Universitaires de Geneve, Geneva (Switzerland); Servei de Radio-oncologia, Institut Oncologic Teknon, Barcelona (Spain)

2011-10-01T23:59:59.000Z

252

NF-kB activity-dependent P-selectin involved in ox-LDL-induced foam cell formation in U937 cell  

SciTech Connect (OSTI)

Highlights: {yields} Ox-LDL induced foam cell formation in the human U937 promonocytic cell line in a dose- and time-dependent manner. {yields} Ox-LDL induced expression of P-selectin through degradation of IkBa and augment of NF-kB activity and protein level during macrophage-derived foam cell formation. {yields} P-selectin and NF-kB may be identified as pivotal regulators of ox-LDL-induced foam cell formation. {yields} Therapy based on the inhibition of P-selectin and NF-kB may complement conventional treatments to prevent atherosclerosis. -- Abstract: Oxidized low-density lipoprotein (ox-LDL) plays a critical role in regulation of atherosclerosis. However, little is known about the role of Nuclear factor kB (NF-kB) activity-dependent P-selectin in ox-LDL-induced foam cell formation during atherosclerosis. In this study, we first investigated ox-LDL induced foam cell formation in the human U937 promonocytic cell line in a dose- and time-dependent manner. Treatment of U937 cells with ox-LDL increased lipid accumulation as well as intracellular cholesterol content. Next, a comparative analysis of gene expression profiling using cDNA microarray and Real-time-PCR indicated that ox-LDL exposure induced, in three treated groups, an extremely marked increase in the mRNA level of P-selectin. Protein levels of P-selectin and its upstream regulators IkBa and NF-kB showed that NF-kB pathway is involved in the ox-LDL-induced foam cell formation. Finally, overexpression of NF-kB significantly accelerated, whereas, inhibition of NF-kB with siRNA remarkably attenuated ox-LDL-induced macrophage-derived foam cell formation. It was concluded that the activity of NF-kB is augmented during macrophage-derived foam cell formation. Activation of NF-kB increased, whereas, inhibition of NF-kB decreased ox-LDL-induced P-selectin expression and lipid accumulation in macrophages, suggesting ox-LDL induced expression of P-selectin through degradation of IkBa and activation of NF-kB in the regulation of foam cell formation.

Wang, Yi, E-mail: wangyi2004a@126.com [Department of Cardiology, Shanghai First People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200080 (China)] [Department of Cardiology, Shanghai First People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200080 (China); Wang, Xiang; Sun, Minghui; Zhang, Zhenyu; Cao, Heng; Chen, Xiaoqing [Department of Cardiology, Shanghai First People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200080 (China)] [Department of Cardiology, Shanghai First People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200080 (China)

2011-08-05T23:59:59.000Z

253

NADPH oxidase/ROS-dependent PYK2 activation is involved in TNF-?-induced matrix metalloproteinase-9 expression in rat heart-derived H9c2 cells  

SciTech Connect (OSTI)

TNF-? plays a mediator role in the pathogenesis of chronic heart failure contributing to cardiac remodeling and peripheral vascular disturbances. The implication of TNF-? in inflammatory responses has been shown to be mediated through up-regulation of matrix metalloproteinase-9 (MMP-9). However, the detailed mechanisms of TNF-?-induced MMP-9 expression in rat embryonic-heart derived H9c2 cells are largely not defined. We demonstrated that in H9c2 cells, TNF-? induced MMP-9 mRNA and protein expression associated with an increase in the secretion of pro-MMP-9. TNF-?-mediated responses were attenuated by pretreatment with the inhibitor of ROS (N-acetyl-L-cysteine, NAC), NADPH oxidase [apocynin (APO) or diphenyleneiodonium chloride (DPI)], MEK1/2 (U0126), p38 MAPK (SB202190), JNK1/2 (SP600125), NF-?B (Bay11-7082), or PYK2 (PF-431396) and transfection with siRNA of TNFR1, p47{sup phox}, p42, p38, JNK1, p65, or PYK2. Moreover, TNF-? markedly induced NADPH oxidase-derived ROS generation in these cells. TNF-?-enhanced p42/p44 MAPK, p38 MAPK, JNK1/2, and NF-?B (p65) phosphorylation and in vivo binding of p65 to the MMP-9 promoter were inhibited by U0126, SB202190, SP600125, NAC, DPI, or APO. In addition, TNF-?-mediated PYK2 phosphorylation was inhibited by NAC, DPI, or APO. PYK2 inhibition could reduce TNF-?-stimulated MAPKs and NF-?B activation. Thus, in H9c2 cells, we are the first to show that TNF-?-induced MMP-9 expression is mediated through a TNFR1/NADPH oxidase/ROS/PYK2/MAPKs/NF-?B cascade. We demonstrated that NADPH oxidase-derived ROS generation is involved in TNF-?-induced PYK2 activation in these cells. Understanding the regulation of MMP-9 expression and NADPH oxidase activation by TNF-? on H9c2 cells may provide potential therapeutic targets of chronic heart failure. - Highlights: TNF-? induces MMP-9 secretion and expression via a TNFR1-dependent pathway. TNF-? induces ROS/PYK2-dependent MMP-9 expression in H9c2 cells. TNF-? induces MMP-9 expression via a NADPH oxidase/ROS-dependent NF-?B signaling. TNF-? activates MAPK phosphorylation through NADPH oxidase/ROS generation.

Yang, Chuen-Mao, E-mail: chuenmao@mail.cgu.edu.tw [Department of Physiology and Pharmacology and Health Aging Research Center, Chang Gung University, Kwei-San, Tao-Yuan, Taiwan (China); Heart Failure Center, Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital at Keelung, Keelung, Taiwan (China); Lee, I-Ta [Department of Physiology and Pharmacology and Health Aging Research Center, Chang Gung University, Kwei-San, Tao-Yuan, Taiwan (China); Department of Anesthetics, Chang Gung Memorial Hospital at Linkou and College of Medicine, Chang Gung University, Kwei-San, Tao-Yuan, Taiwan (China); Hsu, Ru-Chun; Chi, Pei-Ling; Hsiao, Li-Der [Department of Physiology and Pharmacology and Health Aging Research Center, Chang Gung University, Kwei-San, Tao-Yuan, Taiwan (China)

2013-10-15T23:59:59.000Z

254

Aurora A is involved in central spindle assembly through phosphorylation of Ser 19 in P150Glued David Reboutier, Marie-Brengre Troadec, Jean-Yves Cremet, Lucie Chauvin, Vincent Guen, Patrick Salaun, and Claude Prigent  

E-Print Network [OSTI]

Aurora A is involved in central spindle assembly through phosphorylation of Ser 19 in P150Glued endogenous Aurora A: the sequence 59-CCTGTCTTACTGT-39, between positions 729 and 741, was replaced with 59 signaling molecules participate in this regulation, and they include the Aurora A kinase. Some

Paris-Sud XI, Universit de

255

Crime Alert -Theft of Electronic Devices & A Personal Safety Reminder To follow up on the UCPD personal safety update sent to the community on the trends involving the theft of  

E-Print Network [OSTI]

Crime Alert - Theft of Electronic Devices & A Personal Safety Reminder To follow up on the UCPD personal safety update sent to the community on the trends involving the theft of electronic devices device on personal electronic devices. In addition to the recovery of those items, officers assigned

Mills, Allen P.

256

The role of the school social worker in family involvement as identified by family specialists and parents in selected title I schools in North East Independent School District in San Antonio, Texas  

E-Print Network [OSTI]

variables influence parental involvement as reported by parents and family specialists, who are participants of the Parent Academy at the selected Title I elementary schools in the North East ISD, in San Antonio, Texas? The results of this study strongly... parents have on determining the classes set forth for the Parent Academy, as reported by the parents and family specialists who are partici- pants of the Parent Academy at the selected Title I elementary campuses in the North East ISD in San Antonio...

Canada, Gloria Lou

2008-10-10T23:59:59.000Z

257

A Reversible Structural Interconversion Involving [M(H2pdc)2(H2O)2] 2H2O (M Mn, Fe, Co, Ni, Zn, H3pdc 3,5-pyrazoledicarboxylic acid) and the Role  

E-Print Network [OSTI]

A Reversible Structural Interconversion Involving [M(H2pdc)2(H2O)2] ´ 2H2O (M Mn, Fe, Co, Ni, Zn, H3pdc 3,5-pyrazoledicarboxylic acid) and the Role of A Reactive Intermediate [Co(H2pdc)2] Long Pan, Nancy Ching, Xiaoying Huang, and Jing Li*[a] Abstract: A new type of hydrogen bonded networks [M(H2pdc)2

Li, Jing

258

Coal water suspensions involving carbon black  

SciTech Connect (OSTI)

This patent describes a composition comprising: about 65 to 80% by weight of coal particulates with a particle size distribution within 10% of the value calculated in accordance with a Funk distribution which assumes a maximum coal particle size of about 300 microns and minimum coal particle size of about 0.5 microns; about 0.2 to 2% by weight, as based upon the total weight of dry coal, of carbon black having a primary carbon particle size in the range of about 200 to about 900 Angstroms which primary carbon particles are simultaneously bound together to form primary reticulated chains having lengths in the range of about 500 to 30,000 Angstroms; a carrier liquid comprising 20 to 35 wt % water; and from 0.2 to 2.0 wt % of a dispersant selected from the group consisting of ammonium naphthalene sulfonic acid, hexadecyltrimethylammonium bromide, and ammonium lignosulfonate.

Malone, D.P.; Thompson, D.G.

1988-10-25T23:59:59.000Z

259

Increasing Public Involvement in Structural Biology  

E-Print Network [OSTI]

problems, with a sin- gle metric such as energy, are more amenable for gamification than those that are not

Baker, David

260

Learner characteristics involved in distance learning  

SciTech Connect (OSTI)

Distance learning represents a strategy for leveraging resources to solve educational and training needs. Although many distance learning programs have been developed, lessons learned regarding differences between distance learning and traditional education with respect to learner characteristics have not been well documented. Therefore, we conducted a survey of 20 distance learning professionals. The questionnaire was distributed to experts attending the second Distance Learning Conference sponsored by Los Alamos National Laboratory. This survey not only acquired demographic information from each of the respondents but also identified important distance learning student characteristics. Significant distance learner characteristics, which were revealed statistically and which influence the effectiveness of distance learning, include the following: reading level, student autonomy, and self-motivation. Distance learning cannot become a more useful and effective method of instruction without identifying and recognizing learner characteristics. It will be important to consider these characteristics when designing all distance learning courses. This paper will report specific survey findings and their implications for developing distance learning courses. 9 refs., 6 tabs.

Cernicek, A.T.; Hahn, H.A.

1991-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "involvement involvement involvement" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


261

Relativistic kinematics for reactions involving massless particles  

E-Print Network [OSTI]

Some useful kinematical relations for the absorption of a photon by a nucleus and its recoil are derived for the relativistic incident energies. These expressions provided for the relativistic kinematics of photoabsorption reactions, though simple, will be immensely useful for experimentalists as well as theoreticians.

D. N. Basu; Tapan Mukhopadhyay

2007-12-07T23:59:59.000Z

262

Legal Issues Involving Cash Forward Grain Contracts  

E-Print Network [OSTI]

States (though Louisiana has enacted only parts of the UCC). Article 2 of the UCC governs sales transactions. Application of UCC Article 2 to Contracts UCC Article 2 pertains to the sale of goods. ?Goods? includes all things that are movable, as well... that certain types of contracts be in writing. The writing requirement for sales of goods, in most states, is applicable only when the goods have a price of $500 or more. Under another provision of the UCC, there is an overall statute of frauds for every con...

McEowen, Roger A.

1999-06-23T23:59:59.000Z

263

Involvement of peptides in nitrogen fixation  

E-Print Network [OSTI]

and Subsequent Recovery After Nitrate Removal Storage of Nodules Extraction and Analysis of Free Amino Acids and Soyrhizins by Beckman 120B Automatic Amino Acid Analyzer. Localization of Peptides Isolation and Purity Evaluation of Soyrhizin A... 28 INTRODUCTION Peptides and proteins are compounds composed of amino acids and linked by peptide bonds. A well defined distinction between these two does not exist, although compounds of less than 60 amino acid residues (6, QOO daltons...

Ahlgren, Joy Annette

1983-01-01T23:59:59.000Z

264

Diet and Cancer Are Cooked Meats Involved  

ScienceCinema (OSTI)

Diet has been associated with differences in cancer rates in human populations for many years. Mark Knize presents the latest research on cancer causes including work performed at Lawrence Livermore National Laboratory investigating some interesting chemical products created when meat is cooked and how to reduce them. Series: Science on Saturday [10/2006] [Health and Medicine] [Science] [Show ID: 11542

LLNL - University of California Television

2009-09-01T23:59:59.000Z

265

Community Involvement Fund | Department of Energy  

Energy Savers [EERE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious RankCombustion |Energy UsageAUDITVehiclesTankless orAChief Medical

266

Public Involvement Plan | Department of Energy  

Office of Environmental Management (EM)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "of Energy Power.pdf11-161-LNG |September 15,2015 | Department ofThatGrid3of EnergyPublicResumption

267

Sandia National Laboratories: About Sandia: Community Involvement  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary)morphinanInformation Desert Southwest RegionatSearch WelcomeScience SSRL Science Visit ourSafety

268

Sandia National Laboratories: About Sandia: Community Involvement:  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary)morphinanInformation Desert Southwest RegionatSearch WelcomeScience SSRL Science Visit ourSafetyContribution

269

Sandia National Laboratories: About Sandia: Community Involvement:  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary)morphinanInformation Desert Southwest RegionatSearch WelcomeScience SSRL Science Visit

270

Sandia National Laboratories: Community Involvement: Volunteer Programs  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary)morphinanInformation Desert Southwest RegionatSearch WelcomeScience SSRL ScienceCRFCareers StudentsCommunity

271

Mound Site Community Involvement Plan 2012  

Office of Legacy Management (LM)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "ofEarlyEnergyDepartment ofDepartment ofof EnergyYou$0.C. 20545*.MSE Cores Tubay

272

Sandia National Laboratories: About Sandia: Community Involvement:  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsrucLas ConchasPassive SolarEducation Programs: CroSSlinks Science Volunteers CroSSlinks Science

273

Sandia National Laboratories: About Sandia: Community Involvement:  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsrucLas ConchasPassive SolarEducation Programs: CroSSlinks Science Volunteers CroSSlinks

274

Sandia National Laboratories: About Sandia: Community Involvement:  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsrucLas ConchasPassive SolarEducation Programs: CroSSlinks Science Volunteers CroSSlinksEducation

275

Sandia National Laboratories: About Sandia: Community Involvement:  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsrucLas ConchasPassive SolarEducation Programs: CroSSlinks Science Volunteers

276

Sandia National Laboratories: About Sandia: Community Involvement:  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsrucLas ConchasPassive SolarEducation Programs: CroSSlinks Science VolunteersEducation Programs:

277

Sandia National Laboratories: About Sandia: Community Involvement:  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsrucLas ConchasPassive SolarEducation Programs: CroSSlinks Science VolunteersEducation

278

FOIASI - Special Inquiry Review of Allegations Involving  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:YearRound-UpHeat PumpRecord ofESPCofConstruction Management14,2 - In theJuly 17,

279

Decontamination Dressdown at a Transportation Accident Involving  

Office of Environmental Management (EM)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "of EnergyEnergy CooperationRequirements Matrix DOE-STD-3009-2014ofOutline1:Department of

280

UT gets involved at Oak Ridge  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear SecurityTensile Strain Switched Ferromagnetism in Layeredof2014 EIA Energy40081A UmtedGrishamMARC RecordsAPSUT gets

Note: This page contains sample records for the topic "involvement involvement involvement" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


281

Department of Energy Idaho - Public Involvement Opportunity  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary)morphinanInformation Desert Southwest Region service area. The Desert Southwest RegionInside IDWeb Policies No Fear

282

RAPID/Get Involved | Open Energy Information  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia:FAQ < RAPID Jump to: navigation, search RAPIDColorado < RAPID‎ | Geothermal‎ | WellTexas <Get

283

Strategic Public Involvement Products For Review  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear Security Administrationcontroller systemsBiSiteNeutronStrategic Plan The strategic planningStrategic

284

Strategic Public Involvement … Tool Time!  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear Security Administrationcontroller systemsBiSiteNeutronStrategic Plan The strategic planningStrategicLiz

285

Public Involvement and Communications Committee Page 1  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear Security Administration the1 - SeptemberMicroneedlesAdvancedJanuary 13, 2011 FINAL MEETING SUMMARY HANFORD

286

Public Involvement and Communications Committee Page 1  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear Security Administration the1 - SeptemberMicroneedlesAdvancedJanuary 13, 2011 FINAL MEETING SUMMARY HANFORD8, 2012

287

Public Involvement and Communications Committee Page 1  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear Security Administration the1 - SeptemberMicroneedlesAdvancedJanuary 13, 2011 FINAL MEETING SUMMARY HANFORD8,

288

Public Involvement and Communications Committee Page 1  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear Security Administration the1 - SeptemberMicroneedlesAdvancedJanuary 13, 2011 FINAL MEETING SUMMARY HANFORD8,3,

289

Public Involvement and Communications Committee Page 1  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear Security Administration the1 - SeptemberMicroneedlesAdvancedJanuary 13, 2011 FINAL MEETING SUMMARY HANFORD8,3,11,

290

Public Involvement and Communications Committee Page 1  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear Security Administration the1 - SeptemberMicroneedlesAdvancedJanuary 13, 2011 FINAL MEETING SUMMARY

291

On Equilibrium Problems Involving Strongly Pseudomonotone ...  

E-Print Network [OSTI]

ria, in the sense that it includes these problems as particular cases (see for ..... We test the proposed algorithm for this problem with corresponds to the first.

2013-07-05T23:59:59.000Z

292

Fukushima Media Involvement: Lessons Learned and Challenges  

SciTech Connect (OSTI)

Only days after the Fukushima nuclear reactor disaster on March 11, 2011, the Department of Energys Pacific Northwest National Laboratory, or PNNL, found itself in a maelstrom of media attention following announcement of the detection of minute levels of radioactive material originating from the damaged reactors 4,500 miles away. Within days, PNNL had set up a technical team in support of the U.S. governments efforts to assist the devastated country. While a vast amount of information began to flow from Japan, the situation rapidly evolved challenging PNNL scientists and engineers, as well as news media and the general public to deal with a complex and often conflicting information stream. Over the course of about three weeks, PNNLs News & Media Relations staff and its scientists and engineers responded to more than one hundred requests for information, and engaged in dozens of personal interviews with international, national, regional and local media. While many of the interviews and resulting stories were accurate and well done, to say that all communication went flawless would be far from the truth. In the midst of chaos and confusion, which are part of any significant crisis, hiccoughs are sure to occur. Even when communications guidelines are established and agreed-to ahead of time, and spokespeople promise to stay on message and within their areas of expertise, there is no guarantee the ball will not be dropped on occasion. Addressed here is the rest of the story.

Harvey, Geoffrey L.; Koller, Greg L.; Johnson, Wayne L.

2013-04-01T23:59:59.000Z

293

Study on proliferative responses to host Ia antigens in allogeneic bone marrow chimera in mice: sequential analysis of the reactivity and characterization of the cells involved in the responses  

SciTech Connect (OSTI)

Irradiation bone marrow chimeras were established by reconstitution of lethally irradiated AKR mice with C57BL/10 marrow cells to permit serial analysis of the developing reactivities of lymphocytes from such chimeras, (B10----AKR), against donor, host, or third party antigens. We found that substantial proliferative responses to Ia antigens of the recipient strain and also to third party antigens were generated by the thymocytes obtained from the irradiation chimeras at an early stage after bone marrow reconstitution. The majority of the responding thymocytes had surfaces lacking demonstrable peanut agglutinin receptors and were donor type Thy-1+, Ly-2-, and L3T4+ in both anti-recipient and anti-third party MLR. In anti-host responses, however, Ly-2+ thymocytes seemed to be at least partially involved. This capacity of thymus cells to mount a response to antigens of the recipient strain declined shortly thereafter, whereas the capacity to mount MLR against third party antigens persisted. The spleen cells of (B10----AKR) chimeras at the same time developed a more durable capability to exhibit anti-host reactivities and a permanent capability of reacting to third party allo-antigens. The stimulator antigens were Ia molecules on the stimulator cells in both anti-recipient and anti-third party MLR. The responding splenocytes were of donor origin and most of them had Thy-1+, Ly-1+2-, and L3T4+ phenotype.

Iwabuchi, K.; Ogasawara, K.; Ogasawara, M.; Yasumizu, R.; Noguchi, M.; Geng, L.; Fujita, M.; Good, R.A.; Onoe, K.

1987-01-01T23:59:59.000Z

294

Test plan for composting studies involving weight and volume reduction of leaf and stalk biomass: DOE/OTD TTP{number_sign} SR17SS53 {ampersand} TTP{number_sign} SR18SS41  

SciTech Connect (OSTI)

SRTC and a panel of experts from off-site previously determined that composting was the most attractive alternative for reducing the volume and weight of biomass that was slightly radioactive. The SRTC proposed scope of work for Subtask 2 of TTP{number_sign} SR17SS53 and TTP{number_sign} SR18SS41 involves bench scale studies to assess the rates and efficiencies of various composting schemes for volume and weight reduction of leaf and stalk biomass (SB). Ultimately, the data will be used to design a composting process for biomass proposed by MSE for phytoremediation studies at SRS. This could drastically reduce costs for transporting and disposing of contaminated biomass resulting from a future major phytoremediation effort for soil clean-up at the site. The composting studies at SRTC includes collaboration with personnel from the University of Georgia, who will conduct chemical analyses of the plant material after harvest, pre-treatment, and composting for specific time periods. Parameters to be measured will include: lignin, hemicellulose, cellulose, carbon and nitrogen. The overall objective of this project is to identify or develop: (1) an inexpensive source of inoculum (consisting of nutrients and/or microorganisms) capable of significantly enhancing biomass degradation, (2) an optimum range of operating parameters for the composting process, and (3) a process design for the solid state degradation of lignocellulosic biomass contaminated with radionuclides that is superior to existing alternatives for dealing with such waste.

Wilde, E.W.; Kastner, J.; Murphy, C.; Santo Domingo, J.

1997-05-28T23:59:59.000Z

295

Assistant Director of Involvement Office for Student Leadership, Involvement & Community Engagement  

E-Print Network [OSTI]

, website informational updates, Resource Room, Student Organizations Suite, etc. Provide advice and counsel University (ASCSU) administrative assistant, one Student Affairs in Higher Education graduate coordinator, and evaluate training, leadership, organizational, personal development, and diversity education programs

296

Up-regulation of cytosolic phospholipase A{sub 2}{alpha} expression by N,N-diethyldithiocarbamate in PC12 cells; involvement of reactive oxygen species and nitric oxide  

SciTech Connect (OSTI)

Disulfiram (an alcohol-aversive drug) and related compounds are known to provoke several side effects involving behavioral and neurological complications. N,N-diethyldithiocarbamate (DDC) is considered as one of the main toxic species of disulfiram and acts as an inhibitor of superoxide dismutase. Since arachidonic acid (AA) formation is regulated by reactive oxygen species (ROS) and related to toxicity in neuronal cells, we investigated the effects of DDC on AA release and expression of the {alpha} type of cytosolic phospholipase A{sub 2} (cPLA{sub 2}{alpha}) in PC12 cells. Treatment with 80-120 {mu}M DDC that causes a moderate increase in ROS levels without cell toxicity stimulated cPLA{sub 2}{alpha} mRNA and its protein expression. The expression was mediated by extracellular-signal-regulated kinase (ERK1/2), one of the mitogen-activated protein kinases. Treatment with N {sup G} nitro-L-arginine methyl ester (an inhibitor of nitric oxide synthase, 1 mM) and oxy-hemoglobin (a scavenger of nitric oxide, 2 mg/mL) abolished the DDC-induced responses (ERK1/2 phosphorylation and cPLA{sub 2}{alpha} expression). We also showed DDC-induced up-regulation of the mRNA expression of lipocortin 1, an inhibitor of PLA{sub 2}. Furthermore, DDC treatment of the cells enhanced Ca{sup 2+}-ionophore-induced AA release in 30 min, although the effect was limited. Changes in AA metabolism in DDC-treated cells may have a potential role in mediating neurotoxic actions of disulfiram. In this study, we show the first to demonstrate the up-regulation of cPLA{sub 2}{alpha} expression by DDC treatment in neuronal cells.

Akiyama, Nobuteru [Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University, Inohana 1-8-1, Chuo-ku, Chiba 260-8675 (Japan); Nabemoto, Maiko [Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University, Inohana 1-8-1, Chuo-ku, Chiba 260-8675 (Japan); Hatori, Yoshio [Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University, Inohana 1-8-1, Chuo-ku, Chiba 260-8675 (Japan); Nakamura, Hiroyuki [Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University, Inohana 1-8-1, Chuo-ku, Chiba 260-8675 (Japan); Hirabayashi, Tetsuya [Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University, Inohana 1-8-1, Chuo-ku, Chiba 260-8675 (Japan); Fujino, Hiromichi [Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University, Inohana 1-8-1, Chuo-ku, Chiba 260-8675 (Japan); Saito, Takeshi [Department of Health Sciences, Hokkaido University School of Medicine, Sapporo 060-0812 (Japan); Murayama, Toshihiko [Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University, Inohana 1-8-1, Chuo-ku, Chiba 260-8675 (Japan)]. E-mail: murayama@p.chiba-u.ac.jp

2006-09-01T23:59:59.000Z

297

Kinetics and mechanisms of reactions involving small aromatic reactive intermediates  

SciTech Connect (OSTI)

Small aromatic radicals such as C{sub 6}H{sub 5}, C{sub 6}H{sub 5}O and C{sub 6}H{sub 4} are key prototype species of their homologs. C{sub 6}H{sub 5} and its oxidation product, C{sub 6}H{sub 5}O are believed to be important intermediates which play a pivotal role in hydrocarbon combustion, particularly with regard to soot formation. Despite their fundamental importance, experimental data on the reaction mechanisms and reactivities of these species are very limited. For C{sub 6}H{sub 5}, most kinetic data except its reactions with NO and NO{sub 2}, were obtained by relative rate measurements. For C{sub 6}H{sub 5}O, the authors have earlier measured its fragmentation reaction producing C{sub 5}H{sub 5} + CO in shock waves. For C{sub 6}H{sub 4}, the only rate constant measured in the gas phase is its recombination rate at room temperature. The authors have proposed to investigate systematically the kinetics and mechanisms of this important class of molecules using two parallel laser diagnostic techniques--laser resonance absorption (LRA) and resonance enhanced multiphoton ionization mass spectrometry (REMPI/MS). In the past two years, study has been focused on the development of a new multipass adsorption technique--the {open_quotes}cavity-ring-down{close_quotes} technique for kinetic applications. The preliminary results of this study appear to be quite good and the sensitivity of the technique is at least comparable to that of the laser-induced fluorescence method.

Lin, M.C. [Emory Univ., Atlanta, GA (United States)

1993-12-01T23:59:59.000Z

298

arterial feeders involving: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Graduate School has partnered with the Gradu- ate Feeders Scholars program at Florida A&M University to provide under Guidelines: Students applying for funding from Florida State...

299

Host factors involved in viral movement through plants  

E-Print Network [OSTI]

and total lesion count for spinach???????????? IV-3 GFP foci and total lesion count for cowpea???????????? Page 19 43 60 61 64 1 CHAPTER I INTRODUCTION Tomato bushy...) and solid tissue was strained out through a thin layer of cheesecloth. Subsequently, 5x cracking buffer was added in a 1:1 ratio and the mix was boiled for 5 minutes in a water bath. For phosphorylation assays, prior to adding the cracking buffer...

Seaberg, Bonnie Lee

2009-05-15T23:59:59.000Z

300

acquired channelopathy involving: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

systems. We bel... Reiter, E; Sripada, S G; 10.1613jair.1176 2011-01-01 15 Acquired Dyslexia in Japanese: Implications for Reading Theory . Open Access Theses and Dissertations...

Note: This page contains sample records for the topic "involvement involvement involvement" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


301

Metal catalyzed copolymerization processes involving carbon oxides as substrates  

E-Print Network [OSTI]

backbone and electron donating tert-butyl groups in the phenolate rings. This catalyst was used to investigate the effect of altering the nature of the cocatalyst and its concentration. The coupling of carbon monoxide and aziridines has been shown...

Phelps, Andrea Lee

2005-11-01T23:59:59.000Z

302

CHL1 is involved in human breast tumorigenesis and progression  

SciTech Connect (OSTI)

Highlights: CHL1 is down-regulation in breast cancer tissues. Down-regulation of CHL1 is related to high grade. Overexpression of CHL1 inhibits breast cancer cell proliferation and invasion in vitro. CHL1 deficiency induces breast cancer cell proliferation and invasion both in vitro and in vivo. -- Abstract: Neural cell adhesion molecules (CAM) play important roles in the development and regeneration of the nervous system. The L1 family of CAMs is comprised of L1, Close Homolog of L1 (CHL1, L1CAM2), NrCAM, and Neurofascin, which are structurally related trans-membrane proteins in vertebrates. Although the L1CAM has been demonstrated play important role in carcinogenesis and progression, the function of CHL1 in human breast cancer is limited. Here, we found that CHL1 is down-regulated in human breast cancer and related to lower grade. Furthermore, overexpression of CHL1 suppresses proliferation and invasion in MDA-MB-231 cells and knockdown of CHL1 expression results in increased proliferation and invasion in MCF7 cells in vitro. Finally, CHL1 deficiency promotes tumor formation in vivo. Our results may provide a strategy for blocking breast carcinogenesis and progression.

He, Li-Hong [Medical Department of Breast Oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China) [Medical Department of Breast Oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China); Key Laboratory of Breast Cancer Prevention and Treatment of the Ministry of Education, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China); Ma, Qin [Department of Oncology, The General Hospital of Tianjin Medical University, Tianjin (China)] [Department of Oncology, The General Hospital of Tianjin Medical University, Tianjin (China); Shi, Ye-Hui [Medical Department of Breast Oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China) [Medical Department of Breast Oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China); Key Laboratory of Breast Cancer Prevention and Treatment of the Ministry of Education, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China); Ge, Jie; Zhao, Hong-Meng [Key Laboratory of Breast Cancer Prevention and Treatment of the Ministry of Education, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China) [Key Laboratory of Breast Cancer Prevention and Treatment of the Ministry of Education, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China); Breast Surgery, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China); Li, Shu-Fen [Medical Department of Breast Oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China) [Medical Department of Breast Oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China); Key Laboratory of Breast Cancer Prevention and Treatment of the Ministry of Education, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China); Tong, Zhong-Sheng, E-mail: 83352162@qq.com [Medical Department of Breast Oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China) [Medical Department of Breast Oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China); Key Laboratory of Breast Cancer Prevention and Treatment of the Ministry of Education, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China)

2013-08-23T23:59:59.000Z

303

Hepcidin Is Involved in Iron Regulation in the Ischemic Brain  

E-Print Network [OSTI]

and the diameter of the tip was 0.28 mm for rats and 0.18 mm for mice. After 1 h of MCAO, the fish wire was withdrawn from the ICA into the stump of the CCA and the withdrawal was stopped as soon as resistance was felt. The ischemic brain area starts...Wu, Liu G, Yu H-X, et al. (2009) Pre-ischemic treadmill training affects glutamate and gamma aminobutyric acid levels in the striatal dialysate of a rat model of cerebral ischemia. Life Sciences 84: 7. 9. Lipscomb DC, Gorman LG, Traystman RJ, Hurn PD (1998...

Ding, Hui; Yan, Cai-Zhen; Shi, Honglian; Zhao, Ya-Shuo; Chang, Shi-Yang; Yu, Peng; Wu, Wen_Shuang; Zhao, Chen-Yang; Chang, Yan-Zhong; Duan, Xiang-Lin

2011-09-21T23:59:59.000Z

304

An external dose reconstruction involving a radiological dispersal device  

E-Print Network [OSTI]

Council on Radiation Protection and Measurements Report No. 138 (NCRP 2001) indicates that exposures received by first responders will be important for a number of reasons, including planning for the appropriate use of key personnel in an extended...

Hearnsberger, David Wayne

2007-04-25T23:59:59.000Z

305

RIS-M-2240 CLASSIFICATION SYSTEM FOR REPORTING EVENTS INVOLVING  

E-Print Network [OSTI]

Risø National Laboratory, DK 4000 Roskilde, Denmark. #12;INIS-descriptors. BEHAVIOUR; DATA ACQUISITION

306

A Time-Stepping Scheme Involving Constant Coefficient Matrices for ...  

E-Print Network [OSTI]

flow domain, which includes phase field-dependent density/viscosity and a phase field-dependent force term. *Author of ..... k=0 ?k?n?k (J controls the order.

307

Civic Engagement is active involvement in the discourse  

E-Print Network [OSTI]

in Community-based Research Erna Gelles, Institute for Nonprofit Management/ Public Administration Warren

Bertini, Robert L.

308

CURRICULUM HIGHLIGHTS Fellows are actively involved in the  

E-Print Network [OSTI]

experiences are teaching oriented and planned to enhance the fellows' academic careers. Peter G. Szilagyi, M:(585) 2755798 Fax:(585) 2762595 Peter_Szilagyi@urmc.rochester.edu Now accepting applications for 2014

Goldman, Steven A.

309

adolescent alcohol involvement: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

law for which a minor may seek medical care for the prevention, diagnosis or treatment of the medical condition 296 Adolescent Impulsivity: A Mediator between Parental...

310

Patterns of Arm Muscle Activation Involved in Octopus Reaching Movements  

E-Print Network [OSTI]

(EMG)] was measured together with the kinematics of reaching movements. The traveling bend is associated with a propagat- ing wave of muscle activation, with maximal muscle activation slightly preceding with the kinematic variables (velocities and accelerations) re- veals that a significant part of the kinematic

Hochner, Binyamin

311

Tax decisions involving the cost method of inventory valuation  

E-Print Network [OSTI]

88 88 88 8 8 8&8~ ""llXXC t'OiM 8G 8 . i'%18 8 OO 802184 Q8PC O 88 8. OlX!f:"?:OT161'lt o2 f vl8?8ox'T 8884? v Pikl%88 6'M88 "h'. , ' o . ' 58818 8x'8 covv'"'oil&g 41'8888& b j' 88QOQ!''8811'""" 88 OV&X@880 O'XGl'f O8p 0:18 l'118i?8'lOll ~ll... A Thesis XVV~yG" V. 'I~j~l('3 'UA lML~1OUXGP~, '?. C 'K'~A i. :93'. , "3:, ' Ql Qkl ~ dQr' & "X6 @jib&(&P~. "-: Q3. Of. ' 'ci. , ": g3, "~~&G'~ Di~CCC ~P "&j&G~ Q 3 ~ f P j P ZB. jiPQC5 ~K';"POQQOP f f f ~ f f f f f. f f f XV . "?PIj"'1Q ?MG3...

McMenamy, Bobby Benton

2012-06-07T23:59:59.000Z

312

assays involving extraction: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

400 plants to test their anti-obesity activity using porcine pancreatic lipase assay (PPL; triacylglycerol lipase, EC 3.1.1.3) in vitro activity. Among the 400 plants species...

313

Top Management Involvement in the Adoption of Energy Efficiency Projects  

E-Print Network [OSTI]

of Recommendations Top Management * Energy Costs/Sales TopTop Management Top Management * Energy Costs/Sales TopTop Management Top Management * Energy Costs/Sales Top

Blass, Vered; Corbett, Charles J.; Delmas, Magali A; Muthulingam, Suresh

2011-01-01T23:59:59.000Z

314

aquaporin isoforms involved: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

LdAQP2870 have the canonical NPA-NPA motifs, whereas LdAQP putative has a non-canonical NPM-NPA motif. In the carboxyl terminal to the second NPA box of all AQPs except AQP1, a...

315

A primal-dual splitting method for convex optimization involving ...  

E-Print Network [OSTI]

Dec 16, 2011 ... We propose a new first-order splitting algorithm for solving jointly the pri- ... volving the sum of a smooth function with Lipschitzian gradient, a...

2011-12-16T23:59:59.000Z

316

Top Management Involvement in the Adoption of Energy Efficiency Projects  

E-Print Network [OSTI]

Adoption: The Case of Energy- Efficiency Audits. Resource695. Expert Group on Energy Efficiency. 2007. Realizing theDiscount Rates and Energy Efficiency. Contemporary Economic

Blass, Vered; Corbett, Charles J.; Delmas, Magali A; Muthulingam, Suresh

2011-01-01T23:59:59.000Z

317

Close encounters involving free-floating planets in star clusters  

E-Print Network [OSTI]

Instabilities in planetary systems can result in the ejection of planets from their host system, resulting in free-floating planets (FFPs). If this occurs in a star cluster, the FFP may remain bound to the star cluster for some time and interact with the other cluster members until it is ejected. Here, we use $N$-body simulations to characterise close star-planet and planet-planet encounters and the dynamical fate of the FFP population in star clusters containing $500-2000$ single or binary star members. We find that FFPs ejected from their planetary system at low velocities typically leave the star cluster 40% earlier than their host stars, and experience tens of close ($planets before they escape. The fraction of FFPs that experiences a close encounter depends on both the stellar density and the initial velocity distribution of the FFPs. Approximately half of the close encounters occur within the first 30 Myr, and only 10% occur after 100 Myr. The periastron vel...

Wang, Long; Zheng, Xiaochen; Church, Ross P; Davies, Melvyn B

2015-01-01T23:59:59.000Z

318

A time-stepping scheme involving constant coefficient matrices for ...  

E-Print Network [OSTI]

May 18, 2012 ... during pre-processing, so it effectively overcomes the performance ... classical procedure of Lagrangian mechanics based on the least action principle. ..... To complete the discussions from the previous subsection, let us now...

S. Dong

2012-06-21T23:59:59.000Z

319

Argonne National Laboratory has been actively involved in the development  

E-Print Network [OSTI]

electric vehicles. NBTL incorporated a well equipped post-test analysis laboratory that was instrumental independent evaluations on advanced battery technologies that were potential candidates for use in battery-powered

Kemner, Ken

320

Mutation assays involving blood cells that metabolize toxic substances  

DOE Patents [OSTI]

The present invention pertains to a line of human blood cells which have high levels of oxidative activity (such as oxygenase, oxidase, peroxidase, and hydroxylase activity). Such cells grow in suspension culture, and are useful to determine the mutagenicity of xenobiotic substances that are metabolized into toxic or mutagenic substances. The invention also includes mutation assays using these cells, and other cells with similar characteristics. 3 figs.

Crespi, C.L.; Thilly, W.G.

1999-08-10T23:59:59.000Z

Note: This page contains sample records for the topic "involvement involvement involvement" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


321

Quantization of gauge fields in gauges involving extra ghosts  

SciTech Connect (OSTI)

Nielsen's recently proposed quantization rules, with gauge-fixing terms of the form F/sub a/..gamma../sup ab/F/sub b//2..cap alpha.., where ..gamma../sup a/b is field dependent, are shown to lead to an S matrix which is both unitary and gauge independent. The demonstration relies on the canonical form of the path integral.

Henneaux, M.

1983-06-15T23:59:59.000Z

322

aba signaling involved: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

observed at the diploid genome level were not necessarily reflected in synthetic wheats. However, synthetic wheats derived from the parental Ae. tauschii accessions with...

323

Measurement of tau-decays involving eta-mesons  

E-Print Network [OSTI]

The decay tau- --> nu(tau)pi-pi0eta has been observed for the first time using the CLEO-II detector at the Cornell Electron Storage Ring. The measured branching ratio (0.17 +/- 0.02 +/- 0.02)%, agrees with the CVC (conserved ...

Ammar, Raymond G.; Ball, S.; Baringer, Philip S.; Coppage, Don; Copty, N.; Davis, Robin E. P.; Hancock, N.; Kelly, M.; Kwak, Nowhan; Lam, H.

1992-12-01T23:59:59.000Z

324

Security officer tactical training issues involving ESS equipment  

SciTech Connect (OSTI)

Security officer tactical training issues are discussed in relation to the possible implementation of the Tactical Improvement Package (TIP), utilizing the Engagement Simulation System (ESS) equipment, by nuclear power plant licensees for security officer tactical training. The ESS equipment provides the capability to simulate engagement conditions between adversaries armed with weapons which have harmless laser transmitters. A brief discussion of the TIP is presented, along with some concerns and considerations in the use of the TIP.

Rountree, S.L.K.

1984-01-01T23:59:59.000Z

325

Projecting Fatalities in Crashes Involving Older Drivers, 20002025  

E-Print Network [OSTI]

* Donald W. Jones* Timothy Reuscher** Richard S. Schmoyer, Jr.* Lorena F. Truett* *Oak Ridge National Laboratory Oak Ridge, Tennessee **Oak Ridge Institute for Science and Education Oak Ridge, Tennessee October of Transportation under CRADA No. ORNL98-0500 Prepared by the OAK RIDGE NATIONAL LABORATORY Oak Ridge, Tennessee

326

Discovery of ubiquitin ligases involved in cytoplasmic quality control  

E-Print Network [OSTI]

Converging concepts of protein folding in vitro and in vivo.chaperones in cellular protein folding. Current Opinion inof endoplasmic reticulum protein folding. J Cell Biol, 2001.

Heck, Jarrod Wesley

2010-01-01T23:59:59.000Z

327

Farmer involvement in a reforestation research project in Costa Rica  

E-Print Network [OSTI]

. The government of Costa Rica has several reasons not only to subsidize reforestation efforts, but also to create reserves and parks. First, ecotourism brings in hard currency so there is a need to preserve the natural habitat in order to attract and stay..., Pergamon Press. Wallace, G. N. 1993. Wildlands and ecotourism in Latin America. Journal of Forestry. February: 37-40. Winterbottom, R. T. 6 Haselwood, P. T. 1987. Agroforestry and sustainable development: making the connection. Ambio. 16: 100-110. 29...

Toness, Anna Sutherland

2012-06-07T23:59:59.000Z

328

REGULAR ARTICLE Differential display of proteins involved in the neural  

E-Print Network [OSTI]

significantly differential expression patterns in both quantity and quality. With mass spectrometry analysis actin, gamma-actin, actin-related protein 1, tropomyosin 1, and cofilin 1 are related to cell migration: July 28, 2004 Accepted: September 29, 2004 Keywords: Comparative proteomics / Mass spectrometry

Tian, Weidong

329

Involvement of TGF-beta in skin photoaging  

E-Print Network [OSTI]

The goal of this thesis study was to understand the role of TGF-[beta] in skin photoaging, especially in solar elastosis. Solar elastosis, the accumulation of elastotic material in the dermal extracelluar matrix, is a major ...

Choi, Won Seon, 1975-

2005-01-01T23:59:59.000Z

330

arabidopsis thaliana involved: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

occurring variation is an important alternative resource for functional genetics and genomics research.; In a well-characterized collection of Arabidopsis thaliana accessions, we...

331

Fusion reactions involving radioactive beams at GANIL. Gilles de France  

E-Print Network [OSTI]

. In the first case, the high energy beam from the second cyclotron is fragmented onto a target (the production efficiently refocus the species after their production by the fragmentation mechanism, and to optimise energy reaction mechanism) at the Coulomb barrier are possible with that kind of beams. RIBs like 76 Kr

Paris-Sud XI, Université de

332

adipose tissue involvement: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

to -30C and held for 90 min, using a computer-controlled freeze... Davidenko, Natalia; Campbell, J. J.; Thian, E. S.; Watson, C. J,; Cameron, Ruth Elizabeth 2010-01-01 115...

333

airway stenoses involving: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

equine respiratory diseases. RAO is an allergic asthma like disease of the middle-aged horses while the R. equi pneumonia affects only young foals. Respiratory... Kachroo,...

334

Worker Involvement Improves Safety at Hanford Site's Plutonium Finishing Plant  

Broader source: Energy.gov [DOE]

Employees at the Hanford site are working together to find new and innovative ways to stay safe at the Plutonium Finishing Plant, one of the sites most complex decommissioning projects.

335

Multiscale treatment of mechanical contact problems involving thin polymeric layers  

E-Print Network [OSTI]

of energy wasted because of friction, which occurs in particular between mechanical components such as gears, such as providing protective or fouling-resistant coatings for manufacturing [5, 7, 8]. Of special interest

336

ROO: Involving Domain Experts in Authoring OWL Ronald Denaux  

E-Print Network [OSTI]

Authoring, Controlled Natural Language Interfaces, Evaluation of Ontology Building Tools, Geographical process and improve the quality of the resultant ontologies. Recently, controlled language (CL) interfaces domain experts' definition of ontologies in OWL by allowing them to author the ontology in a controlled

Dimitrova, Vania

337

Weak interaction processes in nuclei involving neutrinos and CDM candidates  

SciTech Connect (OSTI)

In this work, we concentrate on the nuclear physics aspects of low-energy neutrinos and in particular on problems related to neutrino detection by terrestrial experiments, neutrino astrophysics and neutrino-nucleus interactions. The detection of low-flux neutrinos, feasible by measuring the energy recoil of the recoiling nucleus with gaseous-detectors having very-low threshold-energy, is carried out in conjunction with direct-detection of cold dark matter events and nonstandard physics searches like the neutrinoless double beta decay.

Kosmas, T. S.; Tsakstara, V. [Theoretical Physics Section, University of Ioannina, GR 45110 Ioannina (Greece); Divari, P. C. [Department of Physical Sciences, Hellenic Army Academy, Vari 16673, Attica (Greece); Sinatkas, J. [Department of Informatics and Computer Technology, TEI of Western Macedonia, GR-52100 Kastoria (Greece)

2009-11-09T23:59:59.000Z

338

artery disease involving: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

E. Lundquist; James P. Ward 72 Association of Common Polymorphisms in GLUT9 Gene with Gout but Not with Coronary Artery Disease in a Large Case-Control Study CiteSeer Summary:...

339

TRANSPORT INVOLVING CONDUCTING FIBERS IN A NON-CONDUCTING MATRIX  

E-Print Network [OSTI]

to sev- eral applications including flexible thin-film transistors, PEM fuel cells, and direct energy, particularly Peltier devices, high electrical conductivity and low thermal conductivity are preferred

Walker, D. Greg

340

aggregates involves smad: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

of these quantum diffusion-limited aggregates vary between 1.43 and 2, depending on the size of the initial wave packet. David B. Johnson; Gonzalo Ordez 2011-11-02 96...

Note: This page contains sample records for the topic "involvement involvement involvement" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


341

TWO PROBLEMS INVOLVING THE NOTION OF PHASE TRANSITION  

E-Print Network [OSTI]

Milas, David Radnell, Cliff Smyth and James and Yuka Taylor, for sharing their time and thoughts with meos and Peter Winkler; and finally my parents, for their endless love and support. iv #12;Dedication To Nastia

Galvin, David

342

atom collisions involving: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

reaction rate constants. The reaction products are identified by in-trap mass spectrometry, revealing the branching ratio between radiative and non-radiative charge exchange...

343

1 INTRODUCTION The use of geosynthetics in modern landfills involves  

E-Print Network [OSTI]

and hydraulic properties. Geosynthetics also can offer technical advantages in relation to traditional liner at the Contrada Sabetta Dam, Italy (Cazzuffi 1987) and to keep an upstream clay seepage control liner from.g. compacted clays for liners, granular media for drainage layers, and various soils for protective

Zornberg, Jorge G.

344

Processing and analysis techniques involving in-vessel material generation  

DOE Patents [OSTI]

In at least one embodiment, the inventive technology relates to in-vessel generation of a material from a solution of interest as part of a processing and/or analysis operation. Preferred embodiments of the in-vessel material generation (e.g., in-vessel solid material generation) include precipitation; in certain embodiments, analysis and/or processing of the solution of interest may include dissolution of the material, perhaps as part of a successive dissolution protocol using solvents of increasing ability to dissolve. Applications include, but are by no means limited to estimation of a coking onset and solution (e.g., oil) fractionating.

Schabron, John F. (Laramie, WY); Rovani, Jr., Joseph F. (Laramie, WY)

2012-09-25T23:59:59.000Z

345

Direct Involvement of Type II Secretion System in Extracellular...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

resulted in slightly yellowish supernatants, different from the pink supernatant of wild type (wt). Comparative proteomic analyses revealed that, although MtrC, OmcA and NrfA,...

346

Indirect Measurements for (p,{alpha}) Reactions Involving Boron Isotopes  

SciTech Connect (OSTI)

Light elements lithium, beryllium and boron (LiBeB) were used in the last years as 'possible probe' for a deeper understanding of some extra-mixing phenomena occurring in young Main-Sequence stars. They are mainly destroyed by (p,{alpha}) reactions and cross section measurements for such channels are then needed. The Trojan Horse Method (THM) allows one to extract the astrophysical S(E)-factor without the experience of tunneling through the Coulomb barrier. In this work a resume of the recent results about the {sup 11}B(p,{alpha}{sub 0}){sup 8}Be and {sup 10}B(p,{alpha}){sup 7}Be reactions is shown.

Lamia, L.; Spitaleri, C.; Romano, S.; Cherubini, S.; Crucilla, V.; Gulino, M.; La Cognata, M.; Pizzone, R. G.; Puglia, S. M. R.; Sergi, M. L.; Tudisco, S.; Tumino, A. [Laboratori Nazionali del Sud, Catania (Italy); Dipartimento di Metodologie Fisiche e Chimiche per l'Ingegneria, Universita di Catania, Catania (Italy); Carlin, N.; Szanto, M. G. del; Liguori Neto, R.; Moura, M. M. de; Munhoz, M. G.; Souza, F. A.; Suaide, A. A. P.; Szanto, E. [Departamento de Fisica Nuclear, Universitade de Sao Paulo, Sao Paulo (Brazil)] (and others)

2008-04-06T23:59:59.000Z

347

Physical Models of Noncovalent Interactions Involving Aromatic Rings  

E-Print Network [OSTI]

-aromatic rings are often quite favourable. For example, the above computed interaction energies for model ethene-benzene and butadiene-benzene complexes are substantial (0.85 and 1.50 kcal mol1 for ethene and butadiene, respectively). In the latter case...

Bloom, Jacob Walter Goldstein

2014-04-17T23:59:59.000Z

348

Introduction The complex life cycle of holometabolous insects involves  

E-Print Network [OSTI]

in the larval fat body, a single-cell thick tissue composed of fat cells. These larval fat cells serve.R.A. and D.K.H., unpublished data). Larvae must therefore acquire enough nutrients not only to fuel by the adult. The unusual developmental history of the larval fat body complicates our understanding of its

Ahmad, Sajjad

349

Opportunities for utility involvement with solar domestic hot water  

SciTech Connect (OSTI)

Solar water heating is one of a number of options that can be considered under utility demand-side management (DSM) programs. Utilities perceive a range of potential benefits for solar water heating in terms of customer service, energy conservation, load management, environmental enhancement, and public relations. The solar industry may benefit from utility marketing efforts, economies of scale, added credibility, financing options, and long-term maintenance arrangements. This paper covers three topics: (1) the energy and demand impacts of solar water heating on utility load profiles based on the results of four studies in the literature, (2) the results of workshops sponsored by the National Renewable Energy Laboratory (NREL) to identify key issues faced by utilities in considering residential solar water heating as a DSM option, (3) several current or planned utility programs to promote solar water heating. 7 refs.

Carlisle, N.; Christensen, C. (National Renewable Energy Lab., Golden, CO (United States)); Barrett, L. (Barrett Consulting Associates, Inc., Colorado Springs, CO (United States))

1992-05-01T23:59:59.000Z

350

TRANSPORT INVOLVING CONDUCTING FIBERS IN A NON-CONDUCTING MATRIX  

E-Print Network [OSTI]

result is a material with high electrical conductivity and low thermal conductivity. Transport Models,2 , J. Rozen3 Introduction Thermal and electrical transport through a low-conductivity matrix containing conversion devices high electrical conductivity and low thermal conductivity are preferred for superior

Walker, D. Greg

351

Voluntary Associations and Their Involvement in Collaborative Forest Management  

E-Print Network [OSTI]

Voluntary associations representing numerous types of recreation users and environmental issues have flourished across the landscape in America. However, the literature has not sufficiently studied these associations and their role in collaborative...

Lu, Jiaying

2012-02-14T23:59:59.000Z

352

activity involves sequential: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Sciences Websites Summary: Sequential Consistency for Heterogeneous-Race-Free DEREK R. HOWER, BRADFORD M. BECKMANN, BENEDICT R: Sequential Consistency for Data-Race-Free (SC for...

353

arms race involving: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Sciences Websites Summary: Sequential Consistency for Heterogeneous-Race-Free DEREK R. HOWER, BRADFORD M. BECKMANN, BENEDICT R: Sequential Consistency for Data-Race-Free (SC for...

354

active student involvement: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

is a COMPETITION for activities that promote professional development and learning among engineering students. 12;How much can-time students of SSE Value-added activities...

355

Get Involved with Home Energy Score | Department of Energy  

Office of Environmental Management (EM)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "of EnergyEnergyENERGY TAX POLICIES7.pdfFuel Cell VehicleEnergy (5Temperatures | DepartmentActivity BookHome

356

Direct Involvement of Type II Secretion System in Extracellular  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation Proposed Newcatalyst phasesDataTranslocation of Shewanella Oneidensis Outer Membrane |

357

Draft Public Involvement Advice for Central Plateau Cleanup  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation Proposed Newcatalyst phasesDataTranslocationDiurnalCommittee Draft Advice -IntegratedV0,

358

Drum Involved in Idaho Incident Not Shippable to WIPP  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation Proposed Newcatalyst phasesDataTranslocationDiurnalCommittee Draftfor $1.14 Per Dennis Hurtt

359

GC GUIDANCE ON BARTER TRANSACTIONS INVOLVING DOE-OWNED URANIUM  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:YearRound-UpHeatMulti-Dimensional Subject: Guidance for natural gas as a feedstock for conversionGC

360

DOE Involvement in Consensus Negotiations for Energy Conservation Standards  

Broader source: Energy.gov (indexed) [DOE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "of EnergyEnergyENERGYWomenthe HouseStudents2.2at Multipleorder supplies orMilestone |Energy

Note: This page contains sample records for the topic "involvement involvement involvement" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


361

Tri-Party Agreement Hanford Public Involvement Plan  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsrucLas ConchasPassiveSubmittedStatusButlerTransportation From modelingTrending: Metal OxoStatement 1

362

Public Involvement and Communications Committee Summaries - Hanford Site  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsrucLas ConchasPassive Solar HomePromising Science for PlutoniumAbout UsPseudogaps,Public

363

Central Plateau Principles Public Involvement Advice DETAILED BACKGROUND  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation Proposed New Substation SitesStanding Friedel Waves,TheoryParliament'v0, 12/9/14 Central

364

Probative Investigation of the Thermal Stability of Wastes Involved in  

Office of Environmental Management (EM)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "of Energy Power.pdf11-161-LNG |September 15,2015 | Department ofThat SavePrice-AndersonFebruary 2014 Waste

365

Workplace Charging Challenge Partner: JLA Public Involvement | Department  

Broader source: Energy.gov (indexed) [DOE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "ofEarlyEnergyDepartment ofDepartment of Energyof EnergyEnergyHertz Hertz hasof Energy JLA

366

Public Involvement in the Environmental Assessment Process | Department of  

Broader source: Energy.gov (indexed) [DOE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "ofEarly Careerlumens_placard-green.epsEnergy1.pdfMarket37963 Vol. 79, No.and/or

367

Paducah WDA CERCLA Process & Public Involvement | Department of Energy  

Office of Environmental Management (EM)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) " ,"ClickPipelinesProvedDecemberInitiativesNationalNuclearRocky Mountain OTCAnnualEndCERCLA Process &

368

OREM continues involvement with workforce development program | Department  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:Year in3.pdfEnergyDepartment of Energy(National1 - AcquisitionOPSAIDJuly 16, 2009

369

Processing and analysis techniques involving in-vessel material generation  

DOE Patents [OSTI]

In at least one embodiment, the inventive technology relates to in-vessel generation of a material from a solution of interest as part of a processing and/or analysis operation. Preferred embodiments of the in-vessel material generation (e.g., in-vessel solid material generation) include precipitation; in certain embodiments, analysis and/or processing of the solution of interest may include dissolution of the material, perhaps as part of a successive dissolution protocol using solvents of increasing ability to dissolve. Applications include, but are by no means limited to estimation of a coking onset and solution (e.g., oil) fractionating.

Schabron, John F. (Laramie, WY); Rovani, Jr., Joseph F. (Laramie, WY)

2011-01-25T23:59:59.000Z

370

Identification and analysis of genes involved in cotton fibre initiation.  

E-Print Network [OSTI]

??Cotton fibres are single-celled hairs, arising from the epidermal surface of the cotton ovule. One factor in determining the length of the mature cotton fibre (more)

Humphries, John A.

2007-01-01T23:59:59.000Z

371

Top Management Involvement in the Adoption of Energy Efficiency Projects  

E-Print Network [OSTI]

The Efficiency Paradox: Bureaucratic and Organizationalenergy efficiency, including organizational and informationefficiency gap generally and the impact of organizational

Blass, Vered; Corbett, Charles J.; Delmas, Magali A; Muthulingam, Suresh

2011-01-01T23:59:59.000Z

372

Local employee honored for community involvement | Department of Energy  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:YearRound-UpHeatMulti-Dimensionalthe10IO1OP001 LetterLight-Duty11.2.1310employee honored for

373

NEPA-Related Public Involvement | Department of Energy  

Energy Savers [EERE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Office of Inspector General Office0-72.pdfGeorgeDoesn't32Department ofMovingJanuary 7,Lessons Learned|NEPA-Related

374

High Sensitivity Proteomics Assisted Discovery of a Novel Operon Involved  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation ProposedUsingFun withconfinement plasmas in thein the Assembly of Photosystem II, a Membrane

375

Emergency Response to a Transportation Accident Involving Radioactive  

Office of Environmental Management (EM)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "of EnergyEnergy CooperationRequirementsDraft EnvironmentalRoadDepartment5-CE-14020)BUILDINGMaterial |

376

Tri-Party Agreement Agencies Annual Hanford Public Involvement Survey  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear SecurityTensile Strain Switched Ferromagnetism in Layered NbS2TopoPortal Hydrogen andTrent Tuckerof 17 Tri-Party

377

RAPID/Best Practices/Public Involvement | Open Energy Information  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia: EnergyPotentialUrbanUtilityScalePVCapacityPulaski County, Kentucky:County,Quogue is aPagePermitting Systems

378

Examples involving shrinking conditions of fixed point theorems  

E-Print Network [OSTI]

, 'NCE December i&70 Major SubDect: M, ther. atics 0 S E z EXP~LES INVOLVI'. &G SHPINEIIlG COEDITIOIJS OP 1 IZED POIl'I I TEEOREi'!S a z lg o o Pi Vl W Sl 5 0 A Thesis by DOUGLAS ANJHZW SJIAPP Approved as to style and content, oy... fash? on. However, shall focus our . i. nterest on the inability of one condition to oe deri ved from another. 'dhen this ' s the case, an example will show the point o " impasse. ACKI1GWLZDG~PJ&TH I wish to thank the following people...

Sharp, Douglas Andrew

2012-06-07T23:59:59.000Z

379

Phosphoproteomics reveals extensive in vivo phosphorylation of Arabidopsis proteins involved  

E-Print Network [OSTI]

have focused on plants. IMAC coupled to mass spec- trometry has been used for small-scale analysis spectrometry-based tech- nology allow the large-scale analysis of protein phosphorylation. Here, we show metal affinity chromatography (IMAC) (1) or other phosphopeptide purification methods such as metal

Hirt, Heribert

380

Fukushima Media Involvement: Lessons Learned and Challenges - 13261  

SciTech Connect (OSTI)

Only days after the Fukushima nuclear reactor disaster on March 11, 2011, the DOE's Pacific Northwest National Laboratory, or PNNL, found itself in a maelstrom of media attention following its announcement of the detection of minute levels of radioactive material originating from the damaged reactors 4,500 miles away. Because PNNL develops state-of-the-art ultra-sensitive radionuclide detection and monitoring systems for national security applications, and has some of the equipment operating on its Richland campus, there was little surprise when one of these sophisticated systems led PNNL to be the first to detect measurable radionuclides in the United States. On Wednesday, March 16, 2011, that system detected minuscule levels of short-lived radioactive xenon, a telltale element derived from either weapons testing or a major reactor disruption. Immediately after the detection was announced, a flurry of inquiries nearly overwhelmed staff as governments, scientific organizations, the general public, and reporters struggled to understand and estimate what impacts this disaster might have on health and environment. Over the course of about three weeks, PNNL's News and Media Relations staff and its scientists and engineers responded to more than 100 requests for information, and engaged in dozens of personal interviews with international, national, regional, and local media. While many of the interviews and resulting stories were accurate and well done, not all communication went flawlessly. In the midst of chaos and confusion, which are part of any significant crisis, hiccoughs are sure to occur. Addressed here is 'the rest of the story'. (authors)

Harvey, Geoffrey L.; Johnson, Wayne L.; Koller, Greg L. [Department of Energy Pacific Northwest National Laboratory (United States)] [Department of Energy Pacific Northwest National Laboratory (United States)

2013-07-01T23:59:59.000Z

Note: This page contains sample records for the topic "involvement involvement involvement" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


381

Structural Studies of Proteins Involved in Diseases of Protein Deposition and a Protein Involved in Nitrogenase Assembly  

E-Print Network [OSTI]

genetic map of the major nif gene cluster from Azotobactergenetic map of the major nif gene cluster from Azotobacterby a previously sequenced nif (nitrogen fixation) gene [12-

Phillips, Aaron Hale

2010-01-01T23:59:59.000Z

382

Optimal Design for Problems Involving Flow and Transport Phenomena in Saturated  

E-Print Network [OSTI]

of well below the ground surface f; f k objective function f c capital costs f o operational costs f R of North Carolina, Chapel Hill, North Carolina 27599-7431, USA Abstract Estimation problems arise routinely in subsurface hydrology for applications that range from water resources management to water quality protection

383

Use of Science in Gulf of Mexico Decision Making Involving Climate Change  

E-Print Network [OSTI]

.............................................................................................................................. 73 table of contents Institute for Science, Technology and Public Policy ? The Bush School ? Texas A&M University x INCREASING THE SALIENCE OF CLIMATE CHANGE FOR GULF OF MEXICO STAKEHOLDERS: EVIDENCE FROM INTERVIEWS, FOCUS GROUPS, NEWSPAPERS...Institute for Science, Technology and Public Policy ? The Bush School ? Texas A&M University Center for Hazards Assessment Response and Technology ? University of New Orleans University of Louisiana-Lafayette Florida A&M University Use...

Vedlitz, Arnold; Alston, Letitia T.; Laska, Shirley B.; Gramling, Robert B.; Harwell, Mark A.; Worthen, Helen D.

2013-12-19T23:59:59.000Z

384

Research Profile The Nanotechnology Group is involved in research in several  

E-Print Network [OSTI]

.nanotechnology.ethz.ch Advanced Microscopy, Instrumentation, Biofuel Cells, Patterning and Directed Assembly MRCMaterials Research science and technology, with a special focus on: surface analysis and the development of advanced sensing colloidal and molecular building blocks) platforms to harvest electric power from human cells (biofuel cell

Sandoghdar, Vahid

385

Examining the Economic Implications and Considerations for Continued Involvement in the Conservation Reserve Program in Texas  

E-Print Network [OSTI]

contract expiration. The options were identified as re-enrollment in CRP, conversion back into crop production, lease land to a tenant as rangeland, or lease land to a tenant as cropland. Latin Hypercube simulation was used to generate a stochastic value...

Schuchard, Laura Mae

2012-10-19T23:59:59.000Z

386

A layman's guide to constitutional aspects of international arms control agreements involving the United States  

SciTech Connect (OSTI)

An initial assessment has been conducted to examine the legal implications and complexities that must be understood and evaluated should the facilities and contractors of the US Department of Energy (DOE) not be exempted from on-site inspections (OSIs) conducted by the Soviet Union under the pending Strategic Arms Reduction Talks (START) Treaty or under future arms control treaties. The assessment looks at the Fourth Amendment rights (right to be secure from unreasonable searches and seizures) of parties at government-owned; government-owned, contractor-operated (GOCO); and private sector facilities that are candidates for Soviet suspect site inspections (SSIs). In particular, the assessment examines the legal consequences of putting at risk classified information designated as either National Security Information (NSI), as cited in relevant executive orders, and/or Restricted Data (RD), which is defined in the Atomic Energy Act of 1954 as amended. Given the potential risk of inadvertent losses of RD and other classified information at DOE sites during OSIs, the Division of Policy and Technical Analysis of DOE's Office of Arms Control (OAC) commissioned this study to aid in understanding some of the legal aspects that must be considered to prepare DOE facilities for possible future OSIs.

Scheinman, L.

1988-12-01T23:59:59.000Z

387

The use of intelligence information to identify the foreign interests of entities involved with DOE programs  

SciTech Connect (OSTI)

This report investigates whether DOE activities could benefit from greater and more consistent access to intelligence information on selected entities with foreign interests. It does not cover dual-use and munition commodities. The investigation determined what information was available from the national intelligence community and law enforcement agencies that would have prevented DOE contracts with selected entities if the information had been available and regulations regarding contracts with selected entities had been enforced.

Not Available

1993-10-22T23:59:59.000Z

388

Differential involvement of endocytic compartments in the biosynthetic traffic of apical  

E-Print Network [OSTI]

Kerry O Cresawn1,5 , Beth A Potter1,5 , Asli Oztan1 , Christopher J Guerriero1 , Gudrun Ihrke3 , James R by adaptor protein complexes (Rodriguez- Boulan et al, 2005). In contrast, apical sorting has been shown anchors or transmembrane residues, and both N-and O-glycans (Rodriguez-Boulan et al, 2005; Ellis et al

Weisz, Ora A.

389

Compositions and methods involving methyladenosine phosphorylase in the diagnosis and treatment of proliferative disorders  

DOE Patents [OSTI]

Disclosed are novel nucleic acid and peptide compositions comprising methylthioadenosine phosphorylase (MTAP) and methods of use for MTAP amino acid sequences and DNA segments comprising MTAP in the diagnosis of human cancers and development of MTAP-specific antibodies. Also disclosed are methods for the diagnosis and treatment of tumors and other proliferative cell disorders, and identification of tumor suppressor genes and gene products from the human 9p21-p22 chromosome region. Such methods are useful in the diagnosis of multiple tumor types such as bladder cancer, lung cancer, breast cancer, pancreatic cancer, brain tumors, lymphomas, gliomas, melanomas, and leukemias.

Olopade, Olufunmilayo I.

2007-03-20T23:59:59.000Z

390

Collaboratives for Wildlife-Wind Turbine Interaction Research: Fostering Multistakeholder Involvement (Poster)  

SciTech Connect (OSTI)

This poster highlights the various wildlife-wind collaboratives (specific to wildlife-wind turbine interaction research) that currently exist. Examples of collaboratives are included along with contact information, objectives, benefits, and ways to advance the knowledge base.

Sinclair, K.

2013-04-01T23:59:59.000Z

391

Atmospheric Aerosols Aging Involving Organic Compounds and Impacts on Particle Properties  

E-Print Network [OSTI]

through sandstorm.2 Examples of anthropogenic sources are vehicle exhaust, plant emission, and construction sites. Some aerosols may have both biogenic and anthropogenic sources. For example, soot aerosols, also known as black carbon, can be produced... with an initial size of 150 nm increases slightly faster than those of soot with the initial size of 80 or 100 nm. Table 1. Properties of Fresh Soot Particles. Dp, nm mp, 10 ?16 g Dve, nm Npp a 82.4 1.47 54.1 20 101 2.34 63.2 32 155 7.77 94.3 105 a...

Qiu, Chong

2013-02-01T23:59:59.000Z

392

VASP involvement in force-mediated adherens junction strengthening Anita S. Kris a  

E-Print Network [OSTI]

a , Alisha L. Sieminski b,* a Department of Biological Engineering, Massachusetts Institute of Technology by application of different force profiles to VE-cadherin-coated magnetic beads attached to endothelial cells- denced by abnormal development of load-bearing tissues such as the heart in the absence of key adhesion

Kamm, Roger D.

393

Major advances have been made in understanding the mechanisms that are involved in the pathogenesis of  

E-Print Network [OSTI]

for the increased demand for insulin. Only about one-third of obese, insulin-resistant indi- viduals actually is also thought to either induce an inflammatory response or to be exacerbated by or associated Center, Harvard Medical School, One Joslin Place, Boston, Massachusetts 02215, USA. emails: MDonath

Cai, Long

394

Use of associated polynomials for division involving polynomials over arbitrary fields  

E-Print Network [OSTI]

+. . . + a p + a p)z+. . . r or h (z) i=O P a. , p z'. t=o (2. 5) Thus h (z) can be represented as an infinite series i h (z) = g b z i i=O (2. 6) The use of a common nomenclature for b. in (2. 6) and (2. 2) i will be justified later. By (2. 5... m over all non-negative i for which i + i +. . . + i r 3 4 m Should m=1, Q . m2, Q. =0 for jk 0 fork&0, j&0whileg=1. If 00 P2 k & 0 while Q. Let [i/2] i-2j h. = $ $ 'k A . ' k Pl , 0 & 1 & ~. (2 2) jk i-j-kj=0 R=O Here A (t) is the r...

Jones, James Edgar

2012-06-07T23:59:59.000Z

395

Abstract--This paper describes results involving the percentage cell lysis of SWLA-2 murine hybridomas  

E-Print Network [OSTI]

]. These techniques have also been used for cell-cell fusion, such as the production of monoclonal antibodies [3, 6, 7 and the pellet was re-suspended at 3 x 105 cells/ml. C. Electrical Equipment and Cuvettes Sinusoidal electric

Stryker, Gabrielle A.

396

Environmental changes are often regional in scope, involving multiple kinds of ecosystems and social systems  

E-Print Network [OSTI]

, and introducing new habitats (Foley et al. 2005, MA 2005).Introductions of nonnative species,and reintroductions). Biogeochemical processes are responding to the addition and redistribution of nutrients (Bennett et al.2001,Foley. Hanson, Timothy K. Kratz, Richard C. Lathrop, and James A. Rusak; and faculty members Emily H. Stanley

Vander Zanden, Jake

397

Investigations of the Fundamental Surface Reactions Involved in the Sorption and Desorption of Radionuclides  

SciTech Connect (OSTI)

Models for describing solution- and surface-phase reactions have been used for 30 years, but only recently applicable to complex surfaces. Duff et al., using micro-XANES, found that Pu was concentrated on Mn-oxide and smectite phases of zeolitic tuff, providing an evaluation of contaminant speciation on surfaces for modeling. Experiments at Los Alamos demonstrated that actinides display varying surface residence time distributions, probably reflective of mineral surface heterogeneity. We propose to investigate the sorption/desorption behavior of radionuclides from mineral surfaces, as effected by microorganisms, employing isolates from Nevada Test Site deep alluvium as a model system. Characterizations will include surface area, particle size distribution, x-ray diffraction (XRD), microprobe analysis, extractions, and microbiology. Surface interactions will be assessed by electron spectroscopy (XPS), x-ray absorption fine structure spectroscopy (XAFS), X-ray emission spectroscopy, transmission electron microscopy (TEM) and Scanning electron microscopy (SEM). Desert Research Institute (DRI), University of Nevada, Reno (UNR), and University of Nevada, Las Vegas (UNLV) researchers will collaborate to enhance scientific infrastructure and the understanding of contaminant behavior on surfaces, with broader implications for the management of DOE sites.

Czerwinski, Ken; Heske, Clemens; Moser, Duane; Misra, Mnoranjan; McMillion, Glen

2011-04-20T23:59:59.000Z

398

Transcriptional regulation of FRUITFULL : a MADS-box gene involved in Arabidopsis fruit development  

E-Print Network [OSTI]

of Science in Biology by Ann Luu Nguyen Committee in charge:Schmidt ii The Thesis of Ann Luu Nguyen is approved, and itArabidopsis fruit development by Ann Luu Nguyen Masters of

Nguyen, Ann Luu

2008-01-01T23:59:59.000Z

399

Search for Neutrinoless {tau} Decays Involving {pi}{sup 0} or {eta} Mesons  

SciTech Connect (OSTI)

We have searched for lepton flavor violating decays of the {tau} lepton using final states with an electron or a muon and one or two {pi}{sup 0} or {eta} mesons but no neutrinos. The data used in the search were collected with the CLEO II detector at the Cornell Electron Storage Ring (CESR) and correspond to an integrated luminosity of 4.68 fb{sup {minus}1} . No evidence for signals was found, resulting in much improved limits on the branching fractions for the one-meson modes and the first upper limits for the two-meson modes. {copyright} {ital 1997} {ital The American Physical Society}

Bonvicini, G.; Cinabro, D.; Greene, R.; Perera, L.P.; Zhou, G.J. [Wayne State University, Detroit, Michigan 48202 (United States)] [Wayne State University, Detroit, Michigan 48202 (United States); Barish, B.; Chadha, M.; Chan, S.; Eigen, G.; Miller, J.S.; OGrady, C.; Schmidtler, M.; Urheim, J.; Weinstein, A.J.; Wuerthwein, F. [California Institute of Technology, Pasadena, California 91125 (United States)] [California Institute of Technology, Pasadena, California 91125 (United States); Asner, D.M.; Bliss, D.W.; Brower, W.S.; Masek, G.; Paar, H.P.; Prell, S.; Sharma, V. [University of California, San Diego, La Jolla, California 92093 (United States)] [University of California, San Diego, La Jolla, California 92093 (United States); Gronberg, J.; Hill, T.S.; Kutschke, R.; Lange, D.J.; Menary, S.; Morrison, R.J.; Nelson, H.N.; Nelson, T.K.; Qiao, C.; Richman, J.D.; Roberts, D.; Ryd, A.; Witherell, M.S. [University of California, Santa Barbara, California 93106 (United States)] [University of California, Santa Barbara, California 93106 (United States); Balest, R.; Behrens, B.H.; Cho, K.; Ford, W.T.; Park, H.; Rankin, P.; Roy, J.; Smith, J.G. [University of Colorado, Boulder, Colorado 80309-0390 (United States)] [University of Colorado, Boulder, Colorado 80309-0390 (United States); Alexander, J.P.; Bebek, C.; Berger, B.E.; Berkelman, K.; Bloom, K.; Cassel, D.G.; Cho, H.A.; Coffman, D.M.; Crowcroft, D.S.; Dickson, M.; Drell, P.S.; Ecklund, K.M.; Ehrlich, R.; Elia, R.; Foland, A.D.; Gaidarev, P.; Galik, R.S.; Gittelman, B.; Gray, S.W.; Hartill, D.L.; Heltsley, B.K.; Hopman, P.I.; Kandaswamy, J.; Kim, P.C.; Kreinick, D.L.; Lee, T.; Liu, Y.; Ludwig, G.S.; Masui, J.; Mevissen, J.; Mistry, N.B.; Ng, C.R.; Nordberg, E.; Ogg, M.; Patterson, J.R.; Peterson, D.; Riley, D.; Soffer, A.; Valant-Spaight, B.; Ward, C. [Cornell University, Ithaca, New York 14853 (United States)] [Cornell University, Ithaca, New York 14853 (United States); Athanas, M.; Avery, P.; Jones, C.D.; Lohner, M.; Prescott, C.; Yelton, J.; Zheng, J. [University of Florida, Gainesville, Florida 32611 (United States)] [University of Florida, Gainesville, Florida 32611 (United States); Brandenburg, G.; Briere, R.A.; Gao, Y.S.; Kim, D.Y.; Wilson, R.; Yamamoto, H. [Harvard University, Cambridge, Massachusetts 02138 (United States)] [Harvard University, Cambridge, Massachusetts 02138 (United States); Browder, T.E.; Li, F.; Li, Y.; Rodriguez, J.L. [University at Hawaii at Manoa, Honolulu, Hawaii 96822 (United States)] [University at Hawaii at Manoa, Honolulu, Hawaii 96822 (United States); Bergfeld, T.; Eisenstein, B.I.; Ernst, J.; and others

1997-08-01T23:59:59.000Z

400

Uniqueness of Solutions to Single-Stage Isobaric Flash Processes Involving  

E-Print Network [OSTI]

of material stability, the Gibbs-Duhem equation, and the Cauchy interlace theorem. Results for the other solutions. Solution curves for the energy balance equation (for the QP case) and the vapor specification. The question of uniqueness arises because the set of model equations that describeseparation processes

Lucia, Angelo

Note: This page contains sample records for the topic "involvement involvement involvement" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
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We encourage you to perform a real-time search of NLEBeta
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401

E-Print Network 3.0 - accidents involving radioactive Sample...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

of Mechanical Engineering, University of Nebraska-Lincoln Collection: Engineering 4 Spatial Data Analysis and Modeling of Radioactively-Contaminated Territories: Lessons...

402

E-Print Network 3.0 - autocrine mechanism involving Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

... Source: Shvartsman, Stanislav "Stas" - Lewis-Sigler Institute for Integrative Genomics & Department of Chemical Engineering, Princeton University Collection: Engineering ;...

403

Journal of Mathematical Chemistry 24 (1998) 123132 123 On the summations involving Wigner rotation matrix  

E-Print Network [OSTI]

matrix elements Shan-Tao Lai a, Pancracio Palting b, Ying-Nan Chiu b and Harris J. Silverstone c rotation matrix elements, we obtain the first kind of summation [4,7]: m (-)m j j j3 m m 0 dj m m() 2 = (-)m j j j3 m m 0 Pj3 (cos ), (1) © J.C. Baltzer AG, Science Publishers #12;124 S.T. Lai et al

Silverstone, Harris J.

404

E-Print Network 3.0 - aspergillus nidulans involves Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Chapter 28 in Aspergillus nidulans: 50 years on (Eds S.D. Martinelli and J.R. Kinghorn); Progress in Summary: 1 Griffith, G.W. (1994). Phenoloxidases. Chapter 28 in...

405

Prolactin signal transduction: involvement of protein kinase C and CA/sup 2 +/  

SciTech Connect (OSTI)

Phorbol esters (PE) in combination with calcium ionophore (A23187) mimic mitogen stimulation of proliferation in lymphocytes. This suggests that protein kinase C (PKC) activation and Ca/sup 2 +/ mobilization may be coupled to cellular proliferation. The mechanism by which prolactin (PRL) triggers a mitogenic response in target tissues is unclear. Therefore, a relationships of PKC activation and Ca/sup 2 +/ mobilization to ornithine decarboxylase (ODC) induction and /sup 3/H-thymidine (/sup 3/H-TdR) incorporation were studied in a rat node lymphoma cell line (Nb/sub 2/) dependent upon PRL for mitogenesis. PE enhanced PRL-stimulated ODC induction and /sup 3/H-TdR incorporation in Nb/sub 2/ cells. Addition of A23187 to cultures containing PE plus PRL increased ODC above PRL alone or PRL plus PE but attenuated proliferation compared to PRL plus PE. PE or PE plus A23187 increased /sup 3/H-TdR incorporation similar to low dose PRL, however this regimen was only 20-25% as effective as optimal PRL. PKC and calmodulin antagonists inhibited both PRL-stimulated ODC and proliferation. A cyclic AMP analogue also inhibited ODC induction and proliferation stimulated either by PRL or PE and A23187. These data strongly suggest that PKC activation and Ca/sup 2 +/ mobilization are coupled to PRL-stimulated ODC induction and proliferation in Nb/sub 2/ cells.

Buckley, A.R.; Kibler, R.; Putnam, C.W.; Russell, D.H.

1986-05-01T23:59:59.000Z

406

Receptor domains involved in signal transduction of prolactin and growth hormone  

SciTech Connect (OSTI)

Prolactin (PRL) and growth hormone (GH) receptors are members of a superfamily that include receptors for a number of cytokines. GH and its receptor form an unusual homodimer consisting of one molecule of GH and two molecules of receptor. A similar homodimer of the PRL receptor is probably required for biological effects to be seen. Using specific assays to measure the functional activity of PRL and GH receptors, a 25 amino acid juxtamembrane region has been identified as essential but not sufficient for normal action. More detailed studies have limited the region to eight amino acids, rich in prolines, that is highly conserved in many members of the receptor superfamily. Finally, GH and PRL have been shown to induce the rapid tyrosine phosphorylation of an associated kinase, Janus kinase 2, and of the receptor itself. 28 refs., 1 fig.

Kelly, P.A.; Edery, M.; Finidori, J. [INSERM, Paris (France)] [and others

1994-12-31T23:59:59.000Z

407

Phylogenomic analysis of the Chlamydomonas genome unmasks proteins potentially involved in photosynthetic function and regulation  

E-Print Network [OSTI]

of DCMU by measuring the electrochromic band shift (520 nm)Analysis carotenoid electrochromic shift (a measure of theby measuring the electrochromic band shift (carotenoid band

2010-01-01T23:59:59.000Z

408

Chloroplast Biogenesis of Photosystem II Cores Involves a Series of Assembly-Controlled Steps  

E-Print Network [OSTI]

of the oxygen evolving enhancer (OEE) proteins, PSBO, P, and Q, on the lumenal side of the membrane. Strikingly of the reaction center subunit D2 is required for the expression of the other reaction center subunit D1, while (Morais et al., 1998). It interacts at a very early step with the reaction center (RC) subunit D2, encoded

409

Production of meson pairs, involving tensor and pseudotensor mesons, in photon-photon collisions  

E-Print Network [OSTI]

Starting from a bound-state model of weakly bound quarks for ($q \\bar{q}$) mesons, we derive a formalism for computing the production or decay of such mesons, whatever the value of their internal orbital angular momentum L. That formalism appears as a natural generalization of the Brodsky-Lepage model (valid only for L=0) that has been widely used in recent years for the computation of exclusive processes in perturbative QCD. We here apply it to the production, in photon-photon collisions, of: i) tensor-meson pairs; ii) pseudotensor-meson pairs; iii) hybrid pairs made of a pion and a pseudotensor meson. The numerical results we obtain allow for some hope of experimentally identifying such pairs, in the charged channels, at high-energy e^+e^- colliders of the next generation, provided integrated luminosities as high as

Houra-Yaou, L; Parisi, J; Murgia, F; Hansson, J

1996-01-01T23:59:59.000Z

410

Metal Catalyzed Formation of Aliphatic Polycarbonates Involving Oxetanes and Carbon Dioxide as Monomers  

E-Print Network [OSTI]

including phosgene and its derivatives. Therefore, it has been of great interest to investigate greener routes for the production of this important class of polymers. Toward this goal, the synthesis of aliphatic polycarbonates via the metal catalyzed...

Moncada, Adriana I.

2011-08-08T23:59:59.000Z

411

E-Print Network 3.0 - aminoguanidine involve reduced Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

007ajpendo.physiology.orgDownloadedfrom 12;reduced in diabetic rats... - Selitto and von Frey filament tests were reduced in diabetic rats compared with controls, which... was...

412

Higgs-radion similarity in production processes involving off-shell fermions  

E-Print Network [OSTI]

The appearance of the radion field, which is associated with the spin-0 metric fluctuations combined in some manner with the scalar stabilizing field, and of the radion, the corresponding lowest Kaluza-Klein (KK) mode, is a generic prediction of stabilized brane world models. In such models the radion plays the role of the dilaton, and its mass may be somewhat smaller than that of all the KK modes of other particles propagating in the multidimensional bulk. Due to its origin, the radion couples to the trace of the energy-momentum tensor of the Standard Model, the interaction Lagrangian of the radion and the Standard Model fermions being similar to that of the SM Higgs-fermion interactions except for additional terms, which come into play only in the case of off-shell fermions. In the present paper it is shown that all the contributions to perturbative amplitudes of physical processes due to these additional terms are canceled out for both massless and massive off-shell fermions. Thus the additional fermion-radion terms in the interaction Lagrangian do not alter any production and decay properties of the radion compared to those of the Higgs boson.

E. Boos; S. Keizerov; E. Rahmetov; K. Svirina

2014-09-09T23:59:59.000Z

413

Polo-like Kinase I is involved in Invasion through Extracellular Matrix  

E-Print Network [OSTI]

Oncogene, 19: 5606-5613, 2000. Figure 2. P^KI VIM-VIM-p-S82 surface ^1 integrin invasionQ Vimentin siRNA A J > J| VIM B-actin 1 OLE. ts iS 120,

Rizki, Aylin

2008-01-01T23:59:59.000Z

414

ensory information processing in the cere-bral cortex has been characterized as involv-  

E-Print Network [OSTI]

simultaneously at multiple regions.79 While near-infrared spectroscopy (NIRS) measures spectroscopic reflection

Miyashita, Yasushi

415

E-Print Network 3.0 - accidental fatalities involving Sample...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

can be particularly threatening due to dangers posed by equipment used... . Consider lockout devices to prevent injury from accidental startup or stored energy. Always...

416

Identification of ARGONAUTES Involved in Antiviral RNA Silencing in Nicotiana benthamiana  

E-Print Network [OSTI]

techniques using the Tobacco rattle virus vector system and posteriorly challenged with a GFP-chimeric virus construct deficient of a silencing suppressor. Unlike in control non-silenced plants, the Tomato bushy stunt virus construct deficient of its P19...

Odokonyero, Denis 1984-

2012-12-11T23:59:59.000Z

417

Power-law distributions in events involving nuclear and radiological materials  

E-Print Network [OSTI]

Nuclear and radiological events are large-impact, hard-to-predict rare events, whose associated probability is exceedingly low. They can exert monumental impacts and lead to grave environmental and economic consequences. ...

Chow, Jijun

2009-01-01T23:59:59.000Z

418

35.1 Introduction Flows.involving.phase.change.are.ubiquitous.in.geophysical.and.  

E-Print Network [OSTI]

.crust.generate.new.rocks.and.segregate.economically.impor- tant.minerals.into.mineable.seams..Groundwater.is.converted.to. steam.in.geothermal.reservoirs.that.can.be.tapped.for.energy.pro- duction..The.oceans.freeze.and.thaw.in.annual.cycles,.moderat- ing.global.temperatures.and.driving.ocean.circulations..Surface. waters.evaporate,.rise,.and.re-condense.to.form.clouds.and.life- giving.rain

Huppert, Herbert

419

Identification of sensitivity genes involved in teratogen-induced neural tube defects  

E-Print Network [OSTI]

that NTDs have a strong genetic component to their development. My project is designed to examine differential expression patterns of genes within the neural tube cells of inbred LM/Bc mouse fetuses following exposure to the known teratogenic agent...

Hayes, Blaine G

2013-02-22T23:59:59.000Z

420

E-Print Network 3.0 - accidents involving external Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Environmental Sciences and Ecology 5 U of L Campus AccidentIncident Report Automobile AccidentIncident Page 1 of 2 University of Lethbridge Summary: U of L Campus...

Note: This page contains sample records for the topic "involvement involvement involvement" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


421

Physical processes involved in strip electrode welding using the method of slatted splicing  

SciTech Connect (OSTI)

Physical processes that take place in a strip electrode during welding using the slatted splicing technique are considered. Flowing of the welding current in the electrode is shown to be the key process which determines electrode heating and melting. Technological receipts are proposed that allow obtaining high-quality welds by the method of slatted splicing.

Bushma, V. O. [Moscow State Technological University 'Stankin' (Russian Federation)

2010-12-15T23:59:59.000Z

422

A system theoretic safety analysis of U.S. Coast Guard aviation mishap involving CG-6505  

E-Print Network [OSTI]

During a 22-month period, between 2008 and 2010, the U.S. Coast Guard experienced seven Class-A aviation mishaps resulting in the loss of 14 Coast Guard aviators and seven Coast Guard aircraft. This represents the highest ...

Hickey, Jon (Jon Patrick)

2012-01-01T23:59:59.000Z

423

A novel instrument for quantitative nanoanalytics involving complementary X-ray methodologies  

SciTech Connect (OSTI)

A novel ultra-high vacuum instrument for X-ray reflectometry and spectrometry-related techniques for nanoanalytics by means of synchrotron radiation has been constructed and commissioned. This versatile instrument was developed by the Physikalisch-Technische Bundesanstalt, Germany's national metrology institute, and includes a 9-axis manipulator that allows for an independent alignment of the samples with respect to all degrees of freedom. In addition, a rotational and translational movement of several photodiodes as well as a translational movement of an aperture system in and out of the beam is provided. Thus, the new instrument enables various analytical techniques based on energy dispersive X-ray detectors such as reference-free X-ray fluorescence analysis (XRF), total-reflection XRF, grazing-incidence XRF in addition to optional X-ray reflectometry measurements or polarization-dependent X-ray absorption fine structure analyses. With this instrument samples having a size of up to 100 mm Multiplication-Sign 100 mm can be analyzed with respect to their mass deposition, elemental or spatial composition, or the species in order to probe surface contamination, layer composition and thickness, the depth profile of matrix elements or implants, the species of nanolayers, nanoparticles or buried interfaces as well as the molecular orientation of bonds. Selected applications of this advanced ultra-high vacuum instrument demonstrate both its flexibility and capability.

Lubeck, J.; Beckhoff, B.; Fliegauf, R.; Holfelder, I.; Hoenicke, P.; Mueller, M.; Pollakowski, B.; Reinhardt, F.; Weser, J. [Physikalisch-Technische Bundesanstalt, Abbestr. 2-12, 10587 Berlin (Germany)

2013-04-15T23:59:59.000Z

424

herbivore-or wound-induced vocabularies have been modified by silencing genes involved  

E-Print Network [OSTI]

(Fig. 1). Mutants whose perception of specific VOCs is impaired (``deaf'' plants) represent another. R. Karban, J. Maron, Ecology 83, 1209 (2002). 16. M. Heil, I. T. Baldwin, Trends Plant Sci. 7, 61

Klee, Harry J.

425

Transcriptional regulation of FRUITFULL : a MADS-box gene involved in Arabidopsis fruit development  

E-Print Network [OSTI]

A genetic framework for fruit patterning in ArabidopsisControl of carpel and fruit development in Arabidopsis.M.F. (2004). Control of fruit patterning in Arabidopsis by

Nguyen, Ann Luu

2008-01-01T23:59:59.000Z

426

Computationally efficient parabolic equation solutions to seismo-acoustic problems involving  

E-Print Network [OSTI]

or low-shear elastic layers Adam M. Metzlera) Applied Research Laboratories, University of Texas at Austin, Austin, Texas 78713 ametzler@arlut.utexas.edu Jon M. Collis Department of Applied Mathematics Society of America PACS numbers: 43.30.Ma [AL] Date Received: November 30, 2012 Date Accepted: February 19

427

E-Print Network 3.0 - anterior prefrontal involvement Sample...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

the role of ... Source: Washington University in St. Louis, Department of Psychology, Cognitive Control and Psychopathology Laboratory Collection: Biology and Medicine 2 Grossberg,...

428

E-Print Network 3.0 - activities involving bacterial Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

5 > >> 81 Microbial Distributions and the Impact of Phosphorus on Bacterial Activity in Lake Erie Summary: Microbial Distributions and the Impact of Phosphorus on Bacterial...

429

Experimental studies of animal movement have traditionally focused upon steady locomotor behaviors (i.e. involving  

E-Print Network [OSTI]

quantification of water velocity fields, and hence momentum, in the wake of the pectoral fins as sunfish executed by devices such as flow tanks, wind tunnels and treadmills. The benefit of this approach is the maintenance variables: wake momentum and pectoral fin stroke timing. Fins on opposite sides of the fish play

Lauder, George V.

430

A Role-involved Conditional Purpose-based Access Control Model  

E-Print Network [OSTI]

control to achieve database security and available in database management systems. The structure helps. Access control is the process of limiting access to the re- sources of a system only to authorized users a secure privacy policy to remove the fear of customers. Thus in an internal management system, a reliable

Paris-Sud XI, Universit de

431

Arabidopsis SPINDLY, a tetratricopeptide repeat protein involved in gibberellin signal transduction in  

E-Print Network [OSTI]

91125 Communicated by Bernard 0. Phinney, University of California, Los Angeles, CA, May 16, 1996 in maize, wheat, and Arabidopsis. The second group, the "slender" mutants, have a recessive overgrowth

Jacobsen, Steve

432

From Isolation to Involvement: Adapting Machine Creativity Software to Support Human-Computer Co-Creation  

E-Print Network [OSTI]

as a creative assistant for a human poet, pro- ducing draft poems that the poet could use as inspiration or raw

Toivonen, Hannu

433

March 2005 Page 1 of 2 CDCResearchInvolvingRadiationReleasesfromtheIdahoNational  

E-Print Network [OSTI]

is the Idaho National Laboratory? The Idaho National Laboratory (INL) is on the upper Snake River Plain radioactive materials released from INL during its operating history? In 1991, the Idaho National Engineering doses from airborne releases over the operating history of the INL were small compared to doses from

434

Corporate Structure Events Involving Regulated Utilities: The Need for a Multidisciplinary, Multijurisdictional Approach  

SciTech Connect (OSTI)

The repeal of PUHCA has occasioned important questions on the appropriate role for regulation in the area of utility corporate structure, including complex process and jurisdictional issues. There is a disproportionality between the importance of these questions and the lack of attention that has been given them by our regulatory and political communities. (author)

Hempling, Scott

2006-08-15T23:59:59.000Z

435

Identification and characterization of the polyketide synthase involved in ochratoxin A biosynthesis in Aspergillus carbonarius  

SciTech Connect (OSTI)

Ochratoxin A (OTA) is a potent mycotoxin produced by Aspergillus and Penicillium species and is a common contaminant of a wide variety of food commodities, with Aspergillus carbonarius being the main producer of OTA contamination in grapes and wine. The molecular structure of OTA is composed of a dihydroisocoumarin ring linked to phenylalanine and, as shown in different producing fungal species, a polyketide synthase (PKS) is a component of the OTA biosynthetic pathway. Similar to observations in other filamentous ascomycetes, the genome sequence of A. carbonarius contains a large number of genes predicted to encode PKSs. In this work a pks gene identified within the putative OTA cluster of A. carbonarius, designated as AcOTApks, was inactivated and the resulting mutant strain was unable to produce OTA, confirming the role of AcOTApks in this biosynthetic pathway. AcOTApks protein is characteristic of the highly reduced (HR)-PKS family, and also contains a putative methyltransferase domain likely responsible for the addition of the methyl group to the OTA polyketide structure. AcOTApks is different from the ACpks protein that we previously described which showed an expression profile compatible with OTA production. We performed phylogenetic analyses of the ?-ketosynthase and acyl-transferase domains of the OTA PKSs which had been identified and characterized in different OTA producing fungal species. The phylogenetic results were similar for both the two domains analyzed and showed that OTA PKS of A. carbonarius, Aspergillus niger, and Aspergillus ochraceus clustered in a monophyletic group with 100% bootstrap support suggesting a common origin, while the other OTA PKSs analyzed were phylogenetically distant. A qRT-PCR assay monitored AcOTApks expression during fungal growth and concomitant production of OTA by A. carbonarius in synthetic grape medium. A clear correlation between the expression profile of AcOTApks and kinetics of OTA production was observed with AcOTApks which reached its maximum level of transcription before OTA accumulation in mycelium reached its highest level, confirming the fact that gene transcription always precedes phenotypic production.

Gallo, Antonia; Knox, Benjamin P.; Bruno, Kenneth S.; Solfrizzo, Michele; Baker, Scott E.; Perrone, Giancarlo

2014-06-02T23:59:59.000Z

436

Search for neutrinoless tau decays involving pi(0) or eta mesons  

E-Print Network [OSTI]

We have searched for lepton flavor violating decays of the tau lepton using final states with an electron Or a muon and one or two pi(0) or eta mesons but no neutrinos. The data used in the search were collected with the CLEO II detector...

Ammar, Raymond G.; Baringer, Philip S.; Bean, Alice; Besson, David Zeke; Coppage, Don; Darling, C.; Davis, Robin E. P.; Hancock, N.; Kotov, S.; Kravchenko, I.; Kwak, Nowhan

1997-08-01T23:59:59.000Z

437

Parallel computation of large least squares problems involving Kronecker products on the Connection Machine 5  

SciTech Connect (OSTI)

The authors present in this paper the implementation and some timing results for a Data Parallel Version of a Kronecker Product Least Squares Code on the Connection Machine 5.

Fulton, C.T.; Wu, L. [Florida Inst. of Tech., Melbourne, FL (United States). Dept. of Applied Mathematics

1995-07-01T23:59:59.000Z

438

E-Print Network 3.0 - association studies involving Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Jonathan Beck Study Coordinator 916-703-0298 jonathan.beck@ucdmc.ucdavis.edu Dr. Marjorie Solomon Associate... Study about Motivation in Learning & Autism Spectrum Disorders The UC...

439

A product involving the $\\beta$-family in stable homotopy theory  

E-Print Network [OSTI]

In the stable homotopy groups $\\pi_{q(p^n+p^m+1)-3}(S)$ of the sphere spectrum $S$ localized at the prime $p$ greater than three, J. Lin constructed an essential family $\\xi_{m,n}$ for $n \\geq m + 2 >5$. In this paper, the authors show that the composite $\\xi_{m,n}\\beta_{s}\\in \\pi_{q(p^n+p^m+sp+s)-5}(S)$ for $2 \\leq s < p$ is non-trivial, where $q=2(p-1)$ and $\\beta_s \\in \\pi_{q(sp+s-1)-2}(S)$ is the known $\\beta$-family. We show our result by explicit combinatorial analysis of the (modified) May spectral sequence.

Liu, Xiugui

2009-01-01T23:59:59.000Z

440

Factors involved in the operation of fiberoptic dynamic lane assignment signs  

E-Print Network [OSTI]

51 51 51 55 55 60 60 63 67 70 72 V. CONCLUSIONS AND RECOMMENDATIONS FINDINGS AND CONCLUSIONS Layout of the Fiberoptic Signs Sign Characteristics . Sign-Signal Coordination Driver Comprehension RECOMMENDATIONS Future Studies . Future... of the various turning movements more efficiently. The application of the concept of Dynamic Lane Assignment Signs (DALAS) to frontage applications is being investigated at Texas Transportation Institute (TTI) since 1989. A changeable message sign (CMS...

Sunkari, Srinivasa R

2012-06-07T23:59:59.000Z

Note: This page contains sample records for the topic "involvement involvement involvement" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


441

Investigation of factors involved in a proposed method of estimating runoff from small drainage areas  

E-Print Network [OSTI]

of assumpt1ons inoluded in the proposed method that oould be in- valM, However, these assumptions were inoluded in other solu tions of th1s problem? After a theoretioal basis ?as formulated, the proposed method seemed to be valM? Ths following proosdure... it was learned that only a few gaged drainage areas existed in Texas that were less than twenty square m1los in area+ After being oonf ranted with this situation, it was deoMed to reinvest%fate the Wpp and reoord sash drainage basin that was comparatively...

Riley, Boyd Tolbert

1962-01-01T23:59:59.000Z

442

Isospin aspects in nuclear reactions involving Ca beams at 25 MeV/nucleon  

SciTech Connect (OSTI)

Isospin dependence of dynamical and thermodynamical properties observed in reactions {sup 40}Ca+ {sup 40,48}Ca and {sup 40}Ca + {sup 46}Ti at 25 MeV/nucleon has been studied. We used the CHIMERA multi-detector array. Strong isospin effects are seen in the isotopic distributions of light nuclei and in the competition between different reaction mechanisms in semi-central collisions. We will show also preliminary results obtained in nuclear collision {sup 48}Ca + {sup 48}Ca at 25MeV/nucleon, having very high N/Z value in the entrance channel (N/Z = 1.4). The enhancement of evaporation residue production confirms the strong role played by the N/Z degree of freedom in nuclear dynamics.

Lombardo, I., E-mail: ilombardo@lns.infn.it; Agodi, C.; Alba, R.; Amorini, F.; Anzalone, A. [INFN Laboratori Nazionali del Sud (Italy); Auditore, L. [Universita di Messina, and INFN-Gr. Coll. Messina, Dipartimento di Fisica (Italy); Berceanu, I. [Institute for Physics and Nuclear Engineering (Romania); Cardella, G. [INFN, Sezione di Catania (Italy); Cavallaro, S. [INFN Laboratori Nazionali del Sud (Italy); Chatterjee, M. B. [Saha Institute of Nuclear Physics (India); Filippo, E. De [INFN, Sezione di Catania (Italy); Di Pietro, A.; Figuera, P. [INFN Laboratori Nazionali del Sud (Italy); Giuliani, G.; Geraci, E.; Grassi, L. [Dipartimento di Fisica e Astronomia Universita di Catania (Italy); Grzeszczuk, A. [University of Silesia, Institute of Physics (Poland); Han, J. [INFN Laboratori Nazionali del Sud (Italy); La Guidara, E. [INFN, Sezione di Catania (Italy); Lanzalone, G. [INFN Laboratori Nazionali del Sud (Italy); and others

2011-11-15T23:59:59.000Z

443

Katherine Tubby For over a decade, numerous volunteers have been involved in a Forest Research (FR)-  

E-Print Network [OSTI]

)- led survey which enables us to monitor the condition of amenity trees in parks, city streets;Our Research Biometrics, Surveys and Statistics overview Woodfuel and biomass energy Simulating and statistics contribute a range of critical scientific approaches, from statistical analysis and data

444

Creating New Leaders: Youth Involvement in Community Activism in South Africa  

E-Print Network [OSTI]

July 27, 2009, Cape Town, South Africa. 23 Sipho,participant, July 27, 2009, Cape Town, South Africa. 245, 2009, Qumbu, South Africa. 25 Paki, youth participant,

Reed, Amber R

2011-01-01T23:59:59.000Z

445

Methyl viologen mediated oxidation-reduction across dihexadecylphosphate vesicles involves transmembrane diffusion  

SciTech Connect (OSTI)

Numerous reports have appeared describing oxidation-reduction across bilayer membranes. Mechanisms proposed for specific systems include the following: (i) electron tunneling across the hydrocarbon barrier between interfacially bound redox partners, (ii) molecular diffusion of bound redox components across the barrier, and (iii) formation of barrier-penetrating aggregates, or electron-conducting channels, across the bilayer. Nonetheless, the actual reaction mechanisms remain obscure due to the general unavailability of transverse diffusion rates, possible loss of compartmentation of reactants, particularly in photochemical systems, and the ambiguities inherent in deducing reaction mechanisms from rate data, which form the primary evidence in most systems studied. The reactions of dihexadecylphosphate (DHP) vesicle-bound methyl viologen (MV/sup 2 +/) describes in this report are unique in allowing deduction of molecular details of a transmembrane redox event from the product composition and microphase distribution. Specifically, they have found that MV/sup 2 +/ bound at the outer vesicle interface mediates reduction of inner-localized MV/sup 2 +/ by dithionite ion in bulk solution in a manner that requires comigration of MV/sup +/ with the electron transferred across the membrane barrier.

Patterson, B.C.; Thompson, D.H.; Hurst, J.K.

1988-05-25T23:59:59.000Z

446

Design of Novel Electron-Rich Organometallic Frameworks Involving Metal-Isocyanide Junctions  

E-Print Network [OSTI]

Aromatic diisocyanides are extensively employed as building blocks in coordination and surface chemistry as charge transport mediators for nanotechnology applications. The first diisocyanoarene-bridged bimetallate system, [{(CO)5V}2(?-CNC6Me4NC)]2...

Maher, Tiffany Rene

2009-01-01T23:59:59.000Z

447

E-Print Network 3.0 - aquaculture industries involvement Sample...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

> >> 1 WHAT IS AQUACULTURE? Aquaculture is the farming of aquatic organisms, including fish, molluscs, Summary: of the stock being cultivated and distinguishes aquaculture from...

448

Congruences involving product of intervals and sets with small multiplicative doubling modulo  

E-Print Network [OSTI]

of Theorem 1 is based on ideas and results of Bourgain, Konya- gin and Shparlinski [2]. Nevertheless

Cilleruelo, Javier

449

Redox Characterization of Proteins Involved in the Mitochondrial Intermembrane Space Pathway  

E-Print Network [OSTI]

Bardwell. 1999. Oxidative protein folding is driven by thecatalyzes oxidative protein folding in mitochondria. Naturecarriers in oxidative protein folding. International journal

Neal, Sonya Elina

2013-01-01T23:59:59.000Z

450

Involvement of Intermediate Sulfur Species in Biological Reduction of Elemental Sulfur under Acidic, Hydrothermal Conditions  

E-Print Network [OSTI]

, Hydrothermal Conditions Eric S. Boyd,a Gregory K. Druschelb Department of Chemistry and Biochemistry, Montana in size, a rate which was influenced by the pH of the me- dium and the presence of organic carbon. Thus, S to serve as a growth-promoting TEA for A. sulfurireducens. Terrestrial and hydrothermal spring source

Ahmad, Sajjad

451

Database, Spatial Spatial databases are the foundation for computer-based applications involving spatially  

E-Print Network [OSTI]

managed using a particular type of software called a database management system (DBMS) that allows, leading to spatio-temporal databases when geometric evolutions are supported. Spatial databases can be implemented in a GIS, in a computer-assisted design (CAD) system coupled with a DBMS, in a universal server

452

Query Plans for Conventional and Temporal Queries Involving Duplicates and Ordering  

E-Print Network [OSTI]

substantially from built- in temporal support in the DBMS. To achieve this, temporal query representation for providing temporal support both via a stand-alone temporal DBMS and via a layer on top of a conventional DBMS. By capturing duplicate removal and retention and order preservation for all queries, as well

Snodgrass, Richard T.

453

Shear and interfacial phenomena involved in reducing process temperature for the recovery of bitumen from  

E-Print Network [OSTI]

of bitumen from Athabasca oil sand Elaine N. Stasiuk1, Laurier L. Schramm1, Harvey Yarranton1, and Bill good bitumen separation and flotation. These are needed, in part, to overcome a bitumen viscosity

Schramm, Laurier L.

454

What are these areas of GeoScience The Geosciences involve the observation and  

E-Print Network [OSTI]

resource reserves, for example oil, water, and metals. Geological processes continuously shape the Earth hazards, and the sustainable development of our planet. Geology is the science of planet Earth, its and dynamics. Both geology and geophysics are used to promote socio- economic development through the search

Schnaufer, Achim

455

Development of regional climate scenarios in the Netherlands -involvement of users  

E-Print Network [OSTI]

the impacts of climate change + for adaptation strategies To ensure that the developed climate scenarios required, because users' requirements can be very diverse and may change over time Meetings with climate of users and limitations to deliver certain types of climate data Adapt information and communication

Haak, Hein

456

Factors affecting the recovery of petroleum in projects involving the injection of liquefied petroleum gases (LPG)  

E-Print Network [OSTI]

- and ? water saturated uncon- solidated sand packs ranging from l. 9 to 22, 8 feet in length. The different series were run at rates varying from 3 to 120 feet per day. A commercial butane - propane mixture and natural gas were used as the solvent... properties are listed in Table I. The cores were packed under water in a vertical position by applying continuous percussion blows along the entire length of the pipe as the sand was added. A filter of glass wool and a fine brass screen were used...

Graham, Gerry A

1961-01-01T23:59:59.000Z

457

E-Print Network 3.0 - anaerobic microorganisms involved Sample...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

absent) soils--such as those that are flooded. Sims... trifida) seeds embedded in agar, some overgrown with soil ... Source: Williams, Martin M. II - Department of Crop...

458

Influence Of Recruitment Methods On Couple Involvement In Transition To Parenthood Intervention  

E-Print Network [OSTI]

resulted in varying prevalence of mens reported violence in their family of origin and womens level of relationship satisfaction. Tests of individual group differences suggested that couples recruited through flyers posted around town and community...

Coca, Vanessa Albina

2009-09-30T23:59:59.000Z

459

Involvement of right STS in audio-visual integration for affective speech  

E-Print Network [OSTI]

Anterior Cingulate cortex - <.010 -2.84 14 -10 14 L Lateral Frontal Pole 10 <.030 -2.05 -44 50 0 R Superior Temporal gyrus 22 <.035 -1.99 70 -6 0 Theta (4-8Hz) AV Unambiguous (A + V) 150-650ms R Thalamus, R Caudate, R Hippocampus, L... .88 60 14 -16 Alpha (8-13Hz) AV Unambiguous (A + V) 50-550ms R Superior Temporal gyrus, R Superior Temporal sulcus, R Temporal Pole 38 <.005 2.99 60 4 -12 R Precentral gyrus, R Postcentral gyrus, R Insula 6 <.005 2...

Hagan, Cindy

2012-03-28T23:59:59.000Z

460

A study of factors involved in quality of homestyle potato chips  

E-Print Network [OSTI]

in means was rather small, 0 . 003 1 and 0 . 0027 respectively. Differences in specific gravity by lot showed to be significant at the 99K confi- dence level (Table 5). Specific gravity of lots of stored potatoes tended to be grouped by cultivar though... 15. 38 62. 86 c b 15. 99 64. 06 b b 17. 15 64. 61 a b 17. 11 68. 57 a a 14. 29 63. 35 d b 31. 16 31. 01 a 30. 72 a 26. 67 b 30. 84 a 5. 98 a 4. 83 b 4. 77 b 4. 82 b 5. 64 ab 0. 6702 30. 79 a b 0. 6746 b 0. 6765 b 27...

Schoelles, Dale Brian

1987-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "involvement involvement involvement" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


461

Optical model potentials involving loosely bound p-shell nuclei around 10 MeV/nucleon  

E-Print Network [OSTI]

.86 1.07 0.7 4 241.36 37.45 0.82 1.06 0.7 5 306.44 39.14 0.81 1.05 0.6 13C (130 MeV)19Be 1 94.2 20.9 0.77 0.99 0.8 2 164.2 23.0 0.67 0.98 0.8 3 226.7 31.9 0.62 0.90 0.8 7Li (63 MeV)19Be 1 134.4 19.82 0.54 1.03 0.9 2 221.6 27.33 0.54 0.92 0.8 3... 276.5 37.3 0.61 0.81 0.7 7Li (63 MeV)113C 1 54.3 29.9 0.92 1.03 0.7 2 99.8 22.0 0.77 1.01 0.8 3 154.8 22.7 0.76 1.00 0.7 4 244.6 26.4 0.68 0.96 0.7 7Li (130 MeV)19Be 1 60.0 17.71 0.86 1.07 0.6 2 129.4 30.7 0.57 0.80 0.9 7Li (130 MeV)113C 1 123...

Trache, L.; Azhari, A.; Clark, HL; Gagliardi, Carl A.; Lui, YW; Mukhamedzhanov, AM; Tribble, Robert E.; Carstoiu, F.

2000-01-01T23:59:59.000Z

462

E-Print Network 3.0 - anaemia potential involvement Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

of erythropoiesis stimulating agents in pre-dialysis patients with anaemia. Data from the French REIN registry... Short title: Adequacy of anaemia correction in ESRD patients...

463

Climate change scenario planning in Alaska's National Parks: Stakeholder involvement in the decision-making process  

SciTech Connect (OSTI)

This article studies the participation of stakeholders in climate change decision-making in Alaska s National Parks. We place stakeholder participation within literatures on environmental and climate change decision-making. We conducted participant observation and interviews in two planning workshops to investigate the decision-making process, and our findings are three-fold. First, the inclusion of diverse stakeholders expanded climate change decision-making beyond National Park Service (NPS) institutional constraints. Second, workshops of the Climate Change Scenario Planning Project (CCSPP) enhanced institutional understandings of participants attitudes towards climate change and climate change decision-making. Third, the geographical context of climate change influences the decisionmaking process. As the first regional approach to climate change decision-making within the NPS, the CCSPP serves as a model for future climate change planning in public land agencies. This study shows how the participation of stakeholders can contribute to robust decisions, may move climate change decision-making beyond institutional barriers, and can provide information about attitudes towards climate change decision-making.

Ernst, Kathleen M [ORNL] [ORNL; Van Riemsdijk, Dr. Micheline [University of Tennessee (UT)] [University of Tennessee (UT)

2013-01-01T23:59:59.000Z

464

Climate Change Scenario Planning in Alaska's National Parks: Stakeholder Involvement in the Decision-Making Process  

SciTech Connect (OSTI)

This article studies the participation of stakeholders in climate change decision-making in Alaska s National Parks. We place stakeholder participation within literatures on environmental and climate change decision-making. We conducted participant observation and interviews in two planning workshops to investigate the decision-making process, and our findings are three-fold. First, the inclusion of diverse stakeholders expanded climate change decision-making beyond National Park Service (NPS) institutional constraints. Second, workshops of the Climate Change Scenario Planning Project (CCSPP) enhanced institutional understandings of participants attitudes towards climate change and climate change decision-making. Third, the geographical context of climate change influences the decision-making process. As the first regional approach to climate change decision-making within the NPS, the CCSPP serves as a model for future climate change planning in public land agencies. This study shows how the participation of stakeholders can contribute to robust decisions, may move climate change decision-making beyond institutional barriers, and can provide information about attitudes towards climate change decision-making.

Ernst, Kathleen M [ORNL] [ORNL; Van Riemsdijk, Dr. Micheline [University of Tennessee (UT)] [University of Tennessee (UT)

2013-01-01T23:59:59.000Z

465

Development of Novel Transition Metal Catalyzed Transformations Involving Small, Strained Carbocycles  

E-Print Network [OSTI]

................................................................................... 84 2.4.3. Synthesis Gas Manifold Construction ..................................................... 85 2.4.4. General Procedure for Ligand Screening................................................. 87 2.4.5. Analytical Procedure...

Sherrill, William M.

2009-01-01T23:59:59.000Z

466

Structure of the Product from a Novel Cyclization Reaction Involving a C(6)-Substituted Uridine Analog  

E-Print Network [OSTI]

ORNL-3794. Oak Ridge National Laboratory, Tennessee, USA. KATTI, S. K . , SESHADRI, T . P. & VISWAMITRA, M . A . ( 1 9 8 1 ) . Acta Cryst. B37, 407-^10. MAIN, P . , HULL, S . E . , LESSINGER, L . , GERMAIN, G . , DECLERCQ, J.-P. & WOOLFSON, M. M...

Wang, Binghe; Takusagawa, Fusao; Mertes, Mathias P.; Bowman-James, Kristin

1993-01-01T23:59:59.000Z

467

MOLECULAR REPRODUCTION AND DEVELOPMENT 73:895905 (2006) Synaptotagmin I Is Involved in the Regulation of  

E-Print Network [OSTI]

in the initiation of a variety of cellular processes collec- tively known as egg activation (Stricker, 1999; Runft exocytosis of cortical granule content proteins (Stricker, 1999; Wessel et al., 2001). Cortical granule of calcium, which is released from intracellular stores in the ER upon sperm binding to the egg (Stricker

Wessel, Gary M.

468

Application of Dissolution Dynamic Nuclear Polarization to the Characterization of Reactions Involving Large Molecules  

E-Print Network [OSTI]

Determination of the pseudo first order reaction rate constant k?, using integrals from each peak of styrene monomer in the three reactions. ........ 88 IV-3 Apparent relaxation rates of the anionic living ends of polystyrene (rP), of polystyrene..., and of styrene monomer (rM). a Both carbons #5 are equivalent in styrene monomer.b These values are overall relaxation rates for the standard polystyrene, not the rates for the specific living chain ends. Since signals of atoms #3 & #4 in polystyrene were...

Lee, Youngbok

2013-03-13T23:59:59.000Z

469

E-Print Network 3.0 - aeruginosa w51d involves Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Desalination and Water... Biofilm formation of Pseudomonas aeruginosa on the surface of a reverse osmosis (RO) ... Source: Elimelech, Menachem - Department of Chemical Engineering,...

470

Supporting information For `Cofactors involved in light-driven charge separation in photosystem I identified by  

E-Print Network [OSTI]

angle with respect to the probe beam. A phase-locked chopper at 500 Hz ensured that every other shot) with a power of 100 nJ focused to a spot of ~150 micrometer in diameter for excitation. A moveable delay line the sample is excited and an absorbance difference spectrum can be calculated. To ensure a fresh spot

van Stokkum, Ivo

471

Local government involvement in long term resource planning for community energy systems. Demand side management  

SciTech Connect (OSTI)

A program was developed to coordinate governmental, research, utility, and business energy savings efforts, and to evaluate future potential actions, based on actual field data obtained during the implementation of Phase I of the State Resource Plan. This has lead to the establishment of a state conservation and energy efficiency fund for the purpose of establishing a DSM Program. By taking a state wide perspective on resource planning, additional savings, including environmental benefits, can be achieved through further conservation and demand management. This effort has already blossomed into a state directive for DSM programs for the natural gas industry.

Not Available

1992-03-01T23:59:59.000Z

472

Utility/Industry Partnerships Involving Distributed Generation Technologies in Evolving Electricity Markets  

E-Print Network [OSTI]

in evolving electric markets and will review both current and emerging distributed generation technologies aimed at retail industrial, commercial and residential markets. This paper will draw upon several Electric Power Research Institutes (EPRI) and member...

Rastler, D. M.

473

Local government involvement in long term resource planning for community energy systems  

SciTech Connect (OSTI)

A program was developed to coordinate governmental, research, utility, and business energy savings efforts, and to evaluate future potential actions, based on actual field data obtained during the implementation of Phase I of the State Resource Plan. This has lead to the establishment of a state conservation and energy efficiency fund for the purpose of establishing a DSM Program. By taking a state wide perspective on resource planning, additional savings, including environmental benefits, can be achieved through further conservation and demand management. This effort has already blossomed into a state directive for DSM programs for the natural gas industry.

Not Available

1992-03-01T23:59:59.000Z

474

Non-Muscle oL-DystroglycanIs Involved in Epithelial Development  

E-Print Network [OSTI]

, ~Oxana Ibraghimov-Beskrovnaya, ~Steven L. Roberds, ~ Kevin P. Campbell, ~and Peter Ekblom* Departments receptors for basement membrane compo- nents such as laminins (Hynes, 1992; Timpl and Brown, 1994), and few

Campbell, Kevin P.

475

Develop a new sustainable business concept for Enviu in 2015 involving 3D printing technology:.  

E-Print Network [OSTI]

??Enviu is a young foundation that scouts and develops WOW! projects. These WOW! Projects are sustainable projects that have the objective to become an independent (more)

Korthals, M.

2011-01-01T23:59:59.000Z

476

Pair correlations in nuclei involved in neutrinoless double beta decay: 76Ge and 76Se  

E-Print Network [OSTI]

Precision measurements were carried out to test the similarities between the ground states of 76Ge and 76Se. The extent to which these two nuclei can be characterized as consisting of correlated pairs of neutrons in a BCS-like ground state was studied. The pair removal (p,t) reaction was measured at the far forward angle of 3 degrees. The relative cross sections are consistent (at the 5% level) with the description of these nuclei in terms of a correlated pairing state outside the N=28 closed shells with no pairing vibrations. Data were also obtained for 74Ge and 78Se.

S. J. Freeman; J. P. Schiffer; A. C. C. Villari; J. A. Clark; C. Deibel; S. Gros; A. Heinz; D. Hirata; C. L. Jiang; B. P. Kay; A. Parikh; P. D. Parker; J. Qian; K. E. Rehm; X. D. Tang; V. Werner; C. Wrede

2007-03-23T23:59:59.000Z

477

E-Print Network 3.0 - approach involving ionic Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Source: Utah, University of - State of Utah Center of Excellence for Biomedical Microfluidics Collection: Engineering 4 Solvation Dynamics and Rotation of Coumarin 153 in...

478

Numerical simulation scheme of one-and two dimensional neural fields involving  

E-Print Network [OSTI]

, UMR 5293 September 5, 2013 1 Introduction Finite transmission speed in physical systems has attracted research for decades. Previous work on heat diffusion has shown experimentally that the transmission speed do not show accordance to classical diffusion theory implying infinite transmission speed. To cope

Boyer, Edmond

479

Management involves coordinating a group of people to accomplish a goal. The Management program at  

E-Print Network [OSTI]

to students in all areas of business. Scholarships range from $250 to the $44,000 Clay Barton Scholarship management, and personal selling. The W. Frank Barton School of Business also offers four master's degree

480

Marketing involves the design, pricing, promotion and distribution of goods and services for consumers.  

E-Print Network [OSTI]

with the Elliott School of Communication, a new minor in Personal Selling is now available. Personal Selling to the $44,000 Clay Barton Scholarship. Admission When you choose to major in Marketing, you are admitted

Note: This page contains sample records for the topic "involvement involvement involvement" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


481

E-Print Network 3.0 - active basement-involved thrust Sample...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

today (Hodges et al., 2001). Nevertheless, when... for the Main Central thrust in Nepal D.M. Robinson* P.G. DeCelles ... Source: Garzione, Carmala N. - Department of Earth...

482

E-Print Network 3.0 - airway proteins involved Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

for Pharmaco-Gene Therapy of the Summary: Fibrosis Airway Liang N. Zhang,1 Phil Karp,2 Christopher J. Gerard,3 Eric Pastor,3 Douglas Laux,4 Keith... of the dysregulated...

483

Abstract--This paper addresses the problem of controlling wind energy conversion systems (WECS) which involve  

E-Print Network [OSTI]

Abstract-- This paper addresses the problem of controlling wind energy conversion systems (WECS-inverter. The goal of control is to maximize wind energy extraction and this needs letting the wind turbine rotor wind energy extraction) only for one wind speed value depending on the considered value of turbine

Paris-Sud XI, Université de

484

Public perceptions of a radioactively contaminated site: concerns, remediation preferences, and desired involvement.  

E-Print Network [OSTI]

sites in 14 states. The St. Louis FUSRAP site properties areadopted for the St. Louis FUSRAP site must be publiclystatement for the St. Louis FUSRAP site. These documents

Feldman, D L; Hanahan, R A

1996-01-01T23:59:59.000Z

485

ABSTRACT: Potential involvement of seed storage proteins in susceptibility to aflatoxin contamination was assessed with in  

E-Print Network [OSTI]

protein (CSP) and zein] were compared with bovine serum albumin (BSA) and collagen. Supplementation was produced when either BSA, CSP, or zein was employed (at 0.5%) as both the sole carbon and the sole nitrogen, aflatoxin production increased with both increasing CSP concentration (0 to 2.0%) and increasing zein

Cotty, Peter J.

486

Laser-driven deflection arrangements and methods involving charged particle beams  

DOE Patents [OSTI]

Systems, methods, devices and apparatus are implemented for producing controllable charged particle beams. In one implementation, an apparatus provides a deflection force to a charged particle beam. A source produces an electromagnetic wave. A structure, that is substantially transparent to the electromagnetic wave, includes a physical structure having a repeating pattern with a period L and a tilted angle .alpha., relative to a direction of travel of the charged particle beam, the pattern affects the force of the electromagnetic wave upon the charged particle beam. A direction device introduces the electromagnetic wave to the structure to provide a phase-synchronous deflection force to the charged particle beam.

Plettner, Tomas (San Ramon, CA); Byer, Robert L. (Stanford, CA)

2011-08-09T23:59:59.000Z

487

E-Print Network 3.0 - ahr repressor involving Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AHR1, AHR2, and AHR repressor. The inability of invertebrate AHR homologs to bind dioxins... Elsevier Science Ireland Ltd. All rights reserved. Keywords: Ah receptor; AHR...

488

Phase-Changing Ionic Liquids: CO2 Capture with Ionic Liquids Involving Phase Change  

SciTech Connect (OSTI)

IMPACCT Project: Notre Dame is developing a new CO2 capture process that uses special ionic liquids (ILs) to remove CO2 from the gas exhaust of coal-fired power plants. ILs are salts that are normally liquid at room temperature, but Notre Dame has discovered a new class of ILs that are solid at room temperature and change to liquid when they bind to CO2. Upon heating, the CO2 is released for storage, and the ILs re-solidify and donate some of the heat generated in the process to facilitate further CO2 release. These new ILs can reduce the energy required to capture CO2 from the exhaust stream of a coal-fired power plant when compared to state-ofthe- art technology.

None

2010-07-01T23:59:59.000Z

489

Managing the diversity of parental involvement in primary schools / Andre Smith.  

E-Print Network [OSTI]

??The word diversity can be described as being different or having differences. Furthermore, it also relates to variety or assortment. Diversity forms an integral part (more)

Smith, Andre

2012-01-01T23:59:59.000Z

490

Application of the SCALE TSUNAMI Tools for the Validation of Criticality Safety Calculations Involving 233U  

SciTech Connect (OSTI)

The Radiochemical Development Facility at Oak Ridge National Laboratory has been storing solid materials containing 233U for decades. Preparations are under way to process these materials into a form that is inherently safe from a nuclear criticality safety perspective. This will be accomplished by down-blending the {sup 233}U materials with depleted or natural uranium. At the request of the U.S. Department of Energy, a study has been performed using the SCALE sensitivity and uncertainty analysis tools to demonstrate how these tools could be used to validate nuclear criticality safety calculations of selected process and storage configurations. ISOTEK nuclear criticality safety staff provided four models that are representative of the criticality safety calculations for which validation will be needed. The SCALE TSUNAMI-1D and TSUNAMI-3D sequences were used to generate energy-dependent k{sub eff} sensitivity profiles for each nuclide and reaction present in the four safety analysis models, also referred to as the applications, and in a large set of critical experiments. The SCALE TSUNAMI-IP module was used together with the sensitivity profiles and the cross-section uncertainty data contained in the SCALE covariance data files to propagate the cross-section uncertainties ({Delta}{sigma}/{sigma}) to k{sub eff} uncertainties ({Delta}k/k) for each application model. The SCALE TSUNAMI-IP module was also used to evaluate the similarity of each of the 672 critical experiments with each application. Results of the uncertainty analysis and similarity assessment are presented in this report. A total of 142 experiments were judged to be similar to application 1, and 68 experiments were judged to be similar to application 2. None of the 672 experiments were judged to be adequately similar to applications 3 and 4. Discussion of the uncertainty analysis and similarity assessment is provided for each of the four applications. Example upper subcritical limits (USLs) were generated for application 1 based on trending of the energy of average lethargy of neutrons causing fission, trending of the TSUNAMI similarity parameters, and use of data adjustment techniques.

Mueller, Don [ORNL; Rearden, Bradley T [ORNL; Hollenbach, Daniel F [ORNL

2009-02-01T23:59:59.000Z

491

Involvement of peroxidases in the Medicago truncatula-Rhizobium meliloti symbiosis  

E-Print Network [OSTI]

The symbiotic interaction between legume plants and bacteria of the family Rhizobiaceae leads to the production of nitrogen fixing nodules on the plant. Nodule production is an expensive process and hence is highly regulated by the plant...

Subramanian, Latha

2000-01-01T23:59:59.000Z

492

E-Print Network 3.0 - apoptosis involving activation Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

in the control of cnidarian bleaching where apoptosis and autophagy act... interconnectivity between apoptosis and autophagy has previously been shown in vertebrates...

493

E-Print Network 3.0 - apoptosis involves constitutive Sample...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

in the control of cnidarian bleaching where apoptosis and autophagy act... interconnectivity between apoptosis and autophagy has previously been shown in vertebrates...

494

Compliance Summary and Community Involvement 2-1 2. Compliance Summary and Community  

E-Print Network [OSTI]

of monitoring conducted under TOA is available at http://www.state.tn.us of permits. Wastewater discharges are regulated by NPDES permits issued by TDEC. Discharges to surface water

Pennycook, Steve

495

Bayesian approaches to bilinear inverse problems involving spatial evidence : color constancy and blind image deconvolution  

E-Print Network [OSTI]

This thesis examines two distinct but related problems in low-level computer vision: color constancy and blind-image deconvolution. The goal of the former is to separate the effect of global illumination from other properties ...

Singh, Barun, 1982-

2006-01-01T23:59:59.000Z

496

Developing governmental decision strategies for determining involvement in highly uncertain, large-scale capital investment projects  

E-Print Network [OSTI]

to the project. Finally, in order to test the model's applicability in assisting governmental decision-makers to rationally allocate resources, the model has been empirically tested by a Westinghouse proposal (concerning offshore floating nuclear power.... INTRODUCTION Statement of the Problem . Purpose of Study . Order of the Study: Scope and Limitations UNCERTAINTY'S EFFECT ON PUBLIC-PRIVATE SECTOR RESOURCE ALLOCATION Background Rationale for Private Sector Resource Allocation . Rationale for Public...

Golden, Robert J

1978-01-01T23:59:59.000Z

497

Involvement in Early Childhood Special Education Among Chinese and Non-Chinese American Parents  

E-Print Network [OSTI]

classification of disabled was operationalized as the child having an individualized educational program (

SooHoo, Tanya

2012-01-01T23:59:59.000Z

498

E-Print Network 3.0 - acid residues involved Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

contacts, however... acid residues with small side-chains (Gly, Ala, Ser, Cys) allow tight helix packing by mediating strong... ) amino acid residues. We propose the use of the...

499

Localization and activation of CaMKII delta isoforms and their involvement in heart failure  

E-Print Network [OSTI]

hypertrophy and heart failure ..CaMKII mediated hypertrophy and heart failure .. I.F.II.C. Preparation of heart tissue extract and cell lysate

Mishra, Shikha

2010-01-01T23:59:59.000Z

500

E-Print Network 3.0 - activities involving ionizing Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Collection: Physics 62 Magnetic field effect on tunnel ionization of deep impurities by terahertz radiation S.D. Ganichev1 Summary: Magnetic field effect on tunnel ionization of...