National Library of Energy BETA

Sample records for interstitial therapy view

  1. Ulcerative colitis and steroid-responsive, diffuse interstitial lung disease

    SciTech Connect (OSTI)

    Balestra, D.J.; Balestra, S.T.; Wasson, J.H.

    1988-07-01

    The authors describe a patient with ulcerative colitis and extracolonic manifestations in whom diffuse interstitial pulmonary disease developed that was responsive to glucocorticoid therapy one year after total proctocolectomy. The patient presented in December 1983 with a subacute course marked by cough and progressive exertional dyspnea, abnormal chest examination results, and a chest roentgenogram that revealed diffuse interstitital and alveolar infiltrates. A transbronchial biopsy specimen revealed a polymorphic interstitial infiltrate, mild interstitial fibrosis without apparent intraluminal fibrosis, and no vasculitis, granulomas, or significant eosinophilic infiltration. Within one week of the initiation of daily high-dose steroid therapy, the patient's symptoms dramatically improved; chest roentgenogram and forced vital capacity (60%) improved at a slower rate. All three measures deteriorated when alternate-day prednisone therapy was started but once again improved until the patient was totally asymptomatic, chest roentgenograms were normal, and forced vital capacity was 80% of the predicted value 2 1/2 years later.

  2. June 2015 Most Viewed Documents for Biology And Medicine | OSTI, US Dept of

    Office of Scientific and Technical Information (OSTI)

    Energy, Office of Scientific and Technical Information June 2015 Most Viewed Documents for Biology And Medicine Measuring dopamine release in the human brain with PET Volkow, N.D. [Brookhaven National Lab., Upton, NY (United States)]|[State Univ. of New York at Stony Brook, Stony Brook, NY (United States). Dept. of Psychiatry]; Fowler, J.S.; Logan, J.; Wang, G.J. [Brookhaven National Lab., Upton, NY (United States)] (1995) 115 Dose and volume specification for reporting interstitial therapy

  3. March 2014 Most Viewed Documents for Biology And Medicine | OSTI, US Dept

    Office of Scientific and Technical Information (OSTI)

    of Energy, Office of Scientific and Technical Information 4 Most Viewed Documents for Biology And Medicine Science Subject Feed Carbon Dioxide Sequestering Using Microalgal Systems Daniel J. Stepan; Richard E. Shockey; Thomas A. Moe; Ryan Dorn (2002) 30 /> Dose and volume specification for reporting interstitial therapy NONE (1997) 29 /> Geothermal demonstration: Zunil food dehydration facility Maldonado, O. (Consultecnia, Guatemala City (Guatemala)); Altseimer, J.; Thayer, G.R. (Los

  4. Most Viewed Documents for Biology and Medicine: December 2014 | OSTI, US

    Office of Scientific and Technical Information (OSTI)

    Dept of Energy, Office of Scientific and Technical Information Most Viewed Documents for Biology and Medicine: December 2014 Dose and volume specification for reporting interstitial therapy NONE (1997) 38 Modification to the Monte Carlo N-Particle (MCNP) Visual Editor (MCNPVised) to Read in Computer Aided Design (CAD) Files Randolph Schwarz; Leland L. Carter; Alysia Schwarz (2005) 38 Drug Retention Times Center for Human Reliability Studies (2007) 34 Degradation of high concentrations of

  5. Di-interstitial defect in silicon revisited

    SciTech Connect (OSTI)

    Londos, C. A.; Antonaras, G.; Chroneos, A.; Department of Materials, Imperial College London, London SW7 2BP

    2013-11-21

    Infrared spectroscopy was used to study the defect spectrum of Cz-Si samples following fast neutron irradiation. We mainly focus on the band at 533 cm{sup ?1}, which disappears from the spectra at ?170 °C, exhibiting similar thermal stability with the Si-P6 electron paramagnetic resonance (EPR) spectrum previously correlated with the di-interstitial defect. The suggested structural model of this defect comprises of two self-interstitial atoms located symmetrically around a lattice site Si atom. The band anneals out following a first-order kinetics with an activation energy of 0.88 ± 0.3 eV. This value does not deviate considerably from previously quoted experimental and theoretical values for the di-interstitial defect. The present results indicate that the 533 cm{sup ?1} IR band originates from the same structure as that of the Si-P6 EPR spectrum.

  6. Impact of interstitial oxygen on the electronic and magnetic...

    Office of Scientific and Technical Information (OSTI)

    interstitial oxygen on the electronic and magnetic structure in superconducting Fe 1 + y Te O x thin films Citation Details In-Document Search Title: Impact of interstitial oxygen...

  7. Bistability of Cation Interstitials in II-VI Semiconductors

    SciTech Connect (OSTI)

    Wei, S. H.; Dalpian, G. M.

    2005-11-01

    The stability of cation interstitials in II-VI semiconductors is studied using ab initio methods. We find that interstitials in the neutral charge state are more stable in the tetrahedral interstitial site near the cation, whereas in the (2+) charge state, they are more stable near the anion. The diffusion energy barrier changes when the defect charge state changes. Therefore, if electrons/holes are taken from the defect level by light, changing its charge state, the interstitial atom will be able to diffuse almost spontaneously due to a reduced diffusion barrier.

  8. Friedel-Like Oscillations from Interstitial Iron in Superconducting

    Office of Scientific and Technical Information (OSTI)

    Fe1+yTe0.62Se0.38 (Journal Article) | SciTech Connect Journal Article: Friedel-Like Oscillations from Interstitial Iron in Superconducting Fe1+yTe0.62Se0.38 Citation Details In-Document Search Title: Friedel-Like Oscillations from Interstitial Iron in Superconducting Fe1+yTe0.62Se0.38 Using polarized and unpolarized neutron scattering we show that interstitial Fe in superconducting Fe$$_{1+y}$$Te$$_{1-x}$$Se$_x$ induces a magnetic Friedel-like oscillation that diffracts at $${\bf

  9. Friedel-Like Oscillations from Interstitial Iron in Superconducting...

    Office of Scientific and Technical Information (OSTI)

    A semi-metallic 5-band model with (frac12frac12) Fermi surface nesting and four fold symmetric super-exchange between interstitial Fe and two in-plane nearest ...

  10. Complexes of self-interstitials with oxygen atoms in Ge

    SciTech Connect (OSTI)

    Khirunenko, L. I.; Pomozov, Yu. V.; Sosnin, M. G.; Abrosimov, N. V.; Riemann, H.

    2014-02-21

    Interactions of germanium self-interstitials with interstitial oxygen atoms in Ge subjected to irradiation at ?80 K and subsequently to annealing have been studied. To distinguish the processes involving vacancies and self-interstitials the doping with tin was used. It was shown that absorption lines with maximum at 602, 674, 713 and 803 cm{sup ?1} are self-interstitials-related. Two lines at 602 and 674, which develop upon annealing in the temperature range 180–240 K, belong to IO complexes, while the bands at 713 and 803 cm{sup ?1}, which emerge after annealing at T>220 K, are associated with I{sub 2}O. It is argued that the annealing of IO occurs by two mechanisms: by dissociation and by diffusion.

  11. First-principles studies on vacancy-modified interstitial diffusion

    Office of Scientific and Technical Information (OSTI)

    mechanism of oxygen in nickel, associated with large-scale atomic simulation techniques (Journal Article) | SciTech Connect First-principles studies on vacancy-modified interstitial diffusion mechanism of oxygen in nickel, associated with large-scale atomic simulation techniques Citation Details In-Document Search Title: First-principles studies on vacancy-modified interstitial diffusion mechanism of oxygen in nickel, associated with large-scale atomic simulation techniques Authors: Fang, H

  12. Migration mechanisms of oxygen interstitial cluste (Journal Article) |

    Office of Scientific and Technical Information (OSTI)

    SciTech Connect Migration mechanisms of oxygen interstitial cluste Citation Details In-Document Search Title: Migration mechanisms of oxygen interstitial cluste Understanding the migration kinetics of radiation- Authors: Xian-Ming Bai ; Anter El-Azab ; Jianguo Yu ; Todd R. Publication Date: 2013-01-01 OSTI Identifier: 1083247 Report Number(s): INL/JOU-13-29349 DOE Contract Number: DE-AC07-05ID14517 Resource Type: Journal Article Resource Relation: Journal Name: Journal of Physics: Condensed

  13. DFT STUDY REVISES INTERSTITIAL CONFIGURATIONS IN HCP Zr

    SciTech Connect (OSTI)

    Samolyuk, German D; Golubov, Stanislav I; Osetskiy, Yury N; Stoller, Roger E

    2012-06-01

    Analysis of experimental result on microstructure evolution in irradiated Zr and alloys has demonstrated that available knowledge on self-interstitial defects in Zr is in contradiction. We therefore have initiated an extensive theoretical and modeling program to clarify this issue. In this report we present first ab initio calculations results of single SIA configurations in Zr. We demonstrate importance of simulations cell size, applied exchange-correlation functional and simulated c/a ratio. The results obtained demonstrate clearly that the most stable configurations are in basal plane and provide some evidences for enhanced interstitial transport along basal planes. The results obtained will be used in generation a new interatomic potential for Zr to be used in large-scale atomistic modeling of mechanisms relevant for radiation-induced microstructure evolution.

  14. Outcomes of High-Dose-Rate Interstitial Brachytherapy in the Treatment of Locally Advanced Cervical Cancer: Long-term Results

    SciTech Connect (OSTI)

    Pinn-Bingham, Melva; Puthawala, Ajmel A.; Syed, A.M. Nisar; Sharma, Anil; DiSaia, Philip; Berman, Michael; Tewari, Krishnansu S.; Randall-Whitis, Leslie; Mahmood, Usama; Ramsinghani, Nilam; Kuo, Jeffrey; Chen, Wen-Pin; McLaren, Christine E.

    2013-03-01

    Purpose: The purpose of this study was to determine locoregional control (LRC), disease-free survival (DFS), and toxicity of high-dose-rate interstitial brachytherapy (HDR-ISBT) in the treatment of locally advanced cervical cancer. Methods and Materials: Between March 1996 and May 2009, 116 patients with cervical cancer were treated. Of these, 106 (91%) patients had advanced disease (International Federation of Gynecology and Obstetrics stage IIB-IVA). Ten patients had stage IB, 48 had stage II, 51 had stage III, and 7 had stage IVA disease. All patients were treated with a combination of external beam radiation therapy (EBRT) to the pelvis (5040 cGy) and 2 applications of HDR-ISBT to a dose of 3600 cGy to the implanted volume. Sixty-one percent of patients also received interstitial hyperthermia, and 94 (81%) patients received chemotherapy. Results: Clinical LRC was achieved in 99 (85.3%) patients. Three-year DFS rates were 59%, 67%, 71%, and 57% for patients with stage IB, II, III, and IVA disease, respectively. The 5-year DFS and overall survival rates for the entire group were 60% and 44%, respectively. Acute and late toxicities were within acceptable limits. Conclusions: Locally advanced cervical cancer patients for whom intracavitary BT is unsuitable can achieve excellent LRC and OS with a combination of EBRT and HDR-ISBT.

  15. Interstitially stabilized phases in the zirconium-nickel system

    SciTech Connect (OSTI)

    MacKay, R.A.

    1993-07-01

    Addition of nonmetal interstitial atoms to Zr-Ni compounds has resulted in several new phases. A single-crystal x-ray study was carried out for Zr{sub 3}NiO. Zr{sub 4}Ni{sub 2}O is a high- temperature phase, forming in samples annealed at 1250 C. Huekel band calculations led to prediction and confirmation of additional phases in more electron rich systems. Other phases studied by XRD are Zr{sub 6}Ni{sub 4}Ti{sub 2}O{sub 0.6}, Nb{sub 6}Ni{sub 6}O, and Nb{sub 6}Ni{sub 4}Ta{sub 2}O{sub 2}. Phases identified by powder diffraction are Nb{sub 4}Ni{sub 2}O, Zr{sub 4}Cu{sub 2}O, and Zr{sub 6}Co{sub 4}Ti{sub 2}O. New Zr kappa phases in space group P6s{sub 3}/mmc were found: Zr{sub 9}Mo{sub 4}SO{sub x} and Zr{sub 9}W{sub 4}(S,Ni)O{sub 3}. A new structure type was discovered with Zr{sub 6}Ni{sub 6}TiSiO{sub 1.8}. In all these interstitially stabilized phases, O is coordinated in Zr octahedral; there are no Ni-O interactions.

  16. Measurements of the oxidation state and concentration of plutonium in interstitial waters of the Irish Sea

    SciTech Connect (OSTI)

    Nelson, D.M.; Lovett, M.B.

    1980-01-01

    The question of plutonium movement in interstitial waters resulting from diffusion along concentration gradients or from advective flow is addressed. The results of measurements of both the concentration and the oxidation state of plutonium in interstitial water collected from sediments near the Windscale discharge, in the solid phases of these sediments and in seawater and suspended solids collected at the coring locations are discussed. (ACR)

  17. JOBAID-VIEWING USER RECORDS

    Office of Energy Efficiency and Renewable Energy (EERE)

    In this job aid you will View To-Do List using Filter and View options, View Completed Work, and View Curriculum Status and Detials areas. 

  18. Most Viewed Documents for Biology and Medicine: September 2014 | OSTI, US

    Office of Scientific and Technical Information (OSTI)

    Dept of Energy, Office of Scientific and Technical Information for Biology and Medicine: September 2014 Modification to the Monte Carlo N-Particle (MCNP) Visual Editor (MCNPVised) to Read in Computer Aided Design (CAD) Files Randolph Schwarz; Leland L. Carter; Alysia Schwarz (2005) 32 Dose and volume specification for reporting interstitial therapy NONE (1997) 28 Carbon Dioxide Sequestering Using Microalgal Systems Daniel J. Stepan; Richard E. Shockey; Thomas A. Moe; Ryan Dorn (2002) 27 Drug

  19. ThreatView

    Energy Science and Technology Software Center (OSTI)

    2007-09-25

    The ThreatView project is based on our prior work with the existing ParaView open-source scientific visualization application. Where ParaView provides a grapical client optimized scientific visualization over the VTK parallel client server architecture, ThreatView provides a client optimized for more generic visual analytics over the same architecture. Because ThreatView is based on the VTK parallel client-server architecture, data sources can reside on remote hosts, and processing and rendering can be performed in parallel. As seenmore » in Fig. 1, ThreatView provides four main methods for visualizing data: Landscape View, which displays a graph using a landscape metaphor where clusters of graph nodes produce "hills" in the landscape; Graph View, which displays a graph using a traditional "ball-and-stick" style; Table View, which displays tabular data in a standard spreadsheet; and Attribute View, which displays a tabular "histogram" of input data - for a selected table column, the Attribute View displays each unique value within the column, and the number of times that value appears in the data. There are two supplemental view types: Text View, which displays tabular data one-record-at-a-time; and the Statistics View, which displays input metadata, such as the number of vertices and edges in a graph, the number of rows in a table, etc.« less

  20. Influence of interstitial Mn on magnetism in room-temperature ferromagnet Mn(1+delta)Sb

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Taylor, Alice E; Berlijn, Tom; Hahn, Steven E; May, Andrew F; Williams, Travis J; Poudel, Lekhanath N; Calder, Stuart A; Fishman, Randy Scott; Stone, Matthew B; Aczel, Adam A; et al

    2015-01-01

    We report elastic and inelastic neutron scattering measurements of the high-TC ferromagnet Mn(1+delta)Sb. Measurements were performed on a large, TC = 434 K, single crystal with interstitial Mn content of delta=0.13. The neutron diffraction results reveal that the interstitial Mn has a magnetic moment, and that it is aligned antiparallel to the main Mn moment. We perform density functional theory calculations including the interstitial Mn, and find the interstitial to be magnetic in agreement with the diffraction data. The inelastic neutron scattering measurements reveal two features in the magnetic dynamics: i) a spin-wave-like dispersion emanating from ferromagnetic Bragg positions (Hmore » K 2n), and ii) a broad, non-dispersive signal centered at forbidden Bragg positions (H K 2n+1). The inelastic spectrum cannot be modeled by simple linear spin-wave theory calculations, and appears to be significantly altered by the presence of the interstitial Mn ions. The results show that the influence of the int« less

  1. Influence of interstitial Mn on magnetism in room-temperature ferromagnet Mn(1+delta)Sb

    SciTech Connect (OSTI)

    Taylor, Alice E; Berlijn, Tom; Hahn, Steven E; May, Andrew F; Williams, Travis J; Poudel, Lekhanath N; Calder, Stuart A; Fishman, Randy Scott; Stone, Matthew B; Aczel, Adam A; Cao, Huibo; Lumsden, Mark D; Christianson, Andrew D

    2015-01-01

    We report elastic and inelastic neutron scattering measurements of the high-TC ferromagnet Mn(1+delta)Sb. Measurements were performed on a large, TC = 434 K, single crystal with interstitial Mn content of delta=0.13. The neutron diffraction results reveal that the interstitial Mn has a magnetic moment, and that it is aligned antiparallel to the main Mn moment. We perform density functional theory calculations including the interstitial Mn, and find the interstitial to be magnetic in agreement with the diffraction data. The inelastic neutron scattering measurements reveal two features in the magnetic dynamics: i) a spin-wave-like dispersion emanating from ferromagnetic Bragg positions (H K 2n), and ii) a broad, non-dispersive signal centered at forbidden Bragg positions (H K 2n+1). The inelastic spectrum cannot be modeled by simple linear spin-wave theory calculations, and appears to be significantly altered by the presence of the interstitial Mn ions. The results show that the influence of the int

  2. Taking the long view

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    2012 Los Alamos Aerial Aerial view of a canyon in Los Alamos, New Mexico. Contact Environmental Communication & Public Outreach P.O. Box 1663 MS M996 Los Alamos, NM 87545 (505)...

  3. Ultra-low contact resistance at an epitaxial metal/oxide heterojunction through interstitial site doping

    SciTech Connect (OSTI)

    Chambers, Scott A.; Gu, Meng; Sushko, Petr V.; Yang, Hao; Wang, Chong M.; Browning, Nigel D.

    2013-08-07

    The ability to form reliable, low-resistance Ohmic contacts is of critical importance to the ongoing development of oxide electronics. Most metals form Schottky barriers when deposited on oxide surfaces. Ohmic contacts rarely occur, and the associated contact resistances are not particularly low. Little is known at an atomistic level about what leads to a good Ohmic contact on a wide-gap oxide. Here we describe the structure of a simple, yet exceptionally low-contact resistance Ohmic metal on an important oxide semiconductor -- epitaxial Cr on Nb-doped SrTiO3(001). Heteroepitaxial growth is accompanied by Cr diffusion into the STO and occupation of interstitial sites within the first few atomic planes. Interstitial Cr is ionized and the resulting electrons occupy the STO conduction band, resulting in effective metallization near the interface.

  4. Chemical composition of interstitial waters from the Japan Sea, ODP Leg 128

    SciTech Connect (OSTI)

    Sturz, A. ); Von Breymann, M.; Dunbar, R. )

    1990-06-01

    During ODP Leg 128, interstitial waters were recovered from Oki Ridge (Site 798) and Kita-Yamato Trough (Site 799) sediment, Sea of Japan. Interstitial water chemical composition reflects diagenetic processes. Evidence indicating organic matter degradation processes includes sulfate depletion, high ammonium concentrations, and shallow maxima of dissolved phosphate. Rapid alkalinity increases in the uppermost sections of the sediments are accompanied by decreases in dissolved calcium, reflecting inorganic calcite precipitation. Authigenic dolomitization results in changes in slopes of the Mg/Ca molar ratios with depth. The opal-A/opal-CT transition is documented by the concentration depth profiles of dissolved silica and lithium. Dolomitization precedes the opal-A/opal-CT transition at both sites. Kita-Yamato Trough sediments show an abrupt change in the compositional character of the pore fluids below 435 mbsf, which coincides with the occurrence of low porosity and high bulk density layers composed of dolomite and opal-CT. These layers impede to some extent diffusional communication with the overlying interstitial waters. The interstitial waters in sediments below 435 mbsf have chloride concentrations of 504-515 mM, significantly lower than that of modern day Japan Sea water (540 mM). The presence of low chloride waters within Miocene age sediments may indicate: (1) diagenetic reactions that involve the release of exchangeable and structural bound water from clay minerals and/or opal-A, (2) Miocene connate brackish lake water, (3) phase separation of hydrothermal fluids associated with rifting, (4) potential effects of clay membrane filtration in a high pressure zone.

  5. Hydrogen passivation of interstitial iron in boron-doped multicrystalline silicon during annealing

    SciTech Connect (OSTI)

    Liu, AnYao; Sun, Chang; Macdonald, Daniel

    2014-11-21

    Effective hydrogenation of interstitial iron in boron-doped multicrystalline silicon wafers is reported. The multicrystalline silicon wafers were annealed with plasma-enhanced chemical vapour deposited silicon nitride films, at temperatures of 400?°C?–?900?°C and for times from minutes to hours. At low temperatures where a combined effect of hydrogenation and precipitation of dissolved Fe is expected, results show that the hydrogenation process dominates the effect of precipitation. The concentrations of dissolved interstitial iron reduce by more than 90% after a 30-min anneal at temperatures between 600 and 900?°C. The most effective reduction occurs at 700?°C, where 99% of the initial dissolved iron is hydrogenated after 30?min. The results show that the observed reductions in interstitial Fe concentrations are not caused by the internal gettering of Fe at structural defects or by an enhanced diffusivity of Fe due to the presence of hydrogen. The hydrogenation process is conjectured to be the pairing of positively charged iron with negatively charged hydrogen, forming less recombination active Fe-H complexes in silicon.

  6. Stereoscopic optical viewing system

    DOE Patents [OSTI]

    Tallman, Clifford S.

    1987-01-01

    An improved optical system which provides the operator a stereoscopic viewing field and depth of vision, particularly suitable for use in various machines such as electron or laser beam welding and drilling machines. The system features two separate but independently controlled optical viewing assemblies from the eyepiece to a spot directly above the working surface. Each optical assembly comprises a combination of eye pieces, turning prisms, telephoto lenses for providing magnification, achromatic imaging relay lenses and final stage pentagonal turning prisms. Adjustment for variations in distance from the turning prisms to the workpiece, necessitated by varying part sizes and configurations and by the operator's visual accuity, is provided separately for each optical assembly by means of separate manual controls at the operator console or within easy reach of the operator.

  7. REACTOR VIEWING APPARATUS

    DOE Patents [OSTI]

    Monk, G.S.

    1959-01-13

    An optical system is presented that is suitable for viewing objects in a region of relatively high radioactivity, or high neutron activity, such as a neutronic reactor. This optical system will absorb neutrons and gamma rays thereby protecting personnel fronm the harmful biological effects of such penetrating radiations. The optical system is comprised of a viewing tube having a lens at one end, a transparent solid member at the other end and a transparent aqueous liquid completely filling the tube between the ends. The lens is made of a polymerized organic material and the transparent solid member is made of a radiation absorbent material. A shield surrounds the tube betwcen the flanges and is made of a gamma ray absorbing material.

  8. Stereoscopic optical viewing system

    DOE Patents [OSTI]

    Tallman, C.S.

    1986-05-02

    An improved optical system which provides the operator with a stereoscopic viewing field and depth of vision, particularly suitable for use in various machines such as electron or laser beam welding and drilling machines. The system features two separate but independently controlled optical viewing assemblies from the eyepiece to a spot directly above the working surface. Each optical assembly comprises a combination of eye pieces, turning prisms, telephoto lenses for providing magnification, achromatic imaging relay lenses and final stage pentagonal turning prisms. Adjustment for variations in distance from the turning prisms to the workpiece, necessitated by varying part sizes and configurations and by the operator's visual accuity, is provided separately for each optical assembly by means of separate manual controls at the operator console or within easy reach of the operator.

  9. The View from HQ

    National Nuclear Security Administration (NNSA)

     NA-ASC-500-07 Issue 2 January 2007 The View from HQ Sitting in airports and planes is risky beyond the obvious dangers now in the news. Uninter- rupted time to think may lead to new ideas. Instinct instructs us that when we hear Wash- ington has some new ideas, the result must be bad. After all, ideas suggest change, which is inherently disruptive. Today the notion of predictivity is on my mind as I am leaving the V&V 2007 meeting in Los Alamos. Predictivity is on my short list of

  10. The View from HQ

    National Nuclear Security Administration (NNSA)

    A publication of the Office of Advanced Simulation & Computing, NNSA Defense Programs NA-ASC-500-07-Issue 3 May 2007 The View from HQ by Dimitri Kusnezov I have been spending much of my time these days thinking about science, technology and engineering and the role of the laboratories and how that will be reflected in the Complex of the future. This is on my mind for two reasons: one is my responsibility to produce a science and technology roadmap for Complex 2030-Defense Program's vision

  11. Strength and formability of ultra-low-carbon Ti-IF steels[Interstitial Free

    SciTech Connect (OSTI)

    Jeong, W.C.

    2000-04-01

    Ultra-low-carbon interstitial free (IF) steel sheets bearing Ti and/or Nb have been extensively used for automotive panels because of superior formability and nonaging properties. It is well known that the interstitial elements such as C and N play important roles in the formability. The lower the contents of the C and N in steel, the better the formability of the steel. The demands for the steel with excellent formability from automotive industry will accelerate the progress in the steelmaking process, leading to the development of the ultra-low-carbon steel. With the advent and installation of improved vacuum degassing equipment in the steelmaking process, it is now possible to consistently produce ultra-low-carbon content of 0.002 to 0.005 wt pct. It is expected that in the near future, the C and N contents can be lowered to as low as 0.001 pct or less. This study is focused on strength and formability in the extremely ultra-low-carbon IF steels containing about 0.001 pct carbon.

  12. Protective laser beam viewing device

    DOE Patents [OSTI]

    Neil, George R.; Jordan, Kevin Carl

    2012-12-18

    A protective laser beam viewing system or device including a camera selectively sensitive to laser light wavelengths and a viewing screen receiving images from the laser sensitive camera. According to a preferred embodiment of the invention, the camera is worn on the head of the user or incorporated into a goggle-type viewing display so that it is always aimed at the area of viewing interest to the user and the viewing screen is incorporated into a video display worn as goggles over the eyes of the user.

  13. False color viewing device

    DOE Patents [OSTI]

    Kronberg, J.W.

    1991-05-08

    This invention consists of a viewing device for observing objects in near-infrared false-color comprising a pair of goggles with one or more filters in the apertures, and pads that engage the face for blocking stray light from the sides so that all light reaching, the user`s eyes come through the filters. The filters attenuate most visible light and pass near-infrared (having wavelengths longer than approximately 700 nm) and a small amount of blue-green and blue-violet (having wavelengths in the 500 to 520 nm and shorter than 435 nm, respectively). The goggles are useful for looking at vegetation to identify different species and for determining the health of the vegetation, and to detect some forms of camouflage.

  14. False color viewing device

    DOE Patents [OSTI]

    Kronberg, James W.

    1992-01-01

    A viewing device for observing objects in near-infrared false-color comprising a pair of goggles with one or more filters in the apertures, and pads that engage the face for blocking stray light from the sides so that all light reaching the user's eyes come through the filters. The filters attenuate most visible light and pass near-infrared (having wavelengths longer than approximately 700 nm) and a small amount of blue-green and blue-violet (having wavelengths in the 500 to 520 nm and shorter than 435 nm, respectively). The goggles are useful for looking at vegetation to identify different species and for determining the health of the vegetation, and to detect some forms of camouflage.

  15. False color viewing device

    DOE Patents [OSTI]

    Kronberg, J.W.

    1992-10-20

    A viewing device for observing objects in near-infrared false-color comprising a pair of goggles with one or more filters in the apertures, and pads that engage the face for blocking stray light from the sides so that all light reaching the user's eyes come through the filters. The filters attenuate most visible light and pass near-infrared (having wavelengths longer than approximately 700 nm) and a small amount of blue-green and blue-violet (having wavelengths in the 500 to 520 nm and shorter than 435 nm, respectively). The goggles are useful for looking at vegetation to identify different species and for determining the health of the vegetation, and to detect some forms of camouflage. 7 figs.

  16. Mountain View Grand | Open Energy Information

    Open Energy Info (EERE)

    Mountain View Grand Jump to: navigation, search Name Mountain View Grand Facility Mountain View Grand Sector Wind energy Facility Type Small Scale Wind Facility Status In Service...

  17. Correlation between the electronic structures and diffusion paths of interstitial defects in semiconductors: The case in CdTe

    SciTech Connect (OSTI)

    Ma, Jie; Yang, Jihui; Da Silva, J. L.F.; Wei, Su-Huai

    2014-10-30

    Using first-principles calculations, we study the diffusions of interstitial defects Cd, Cu, Te, and Cl in CdTe. We find that the diffusion behavior is strongly correlated with the electronic structure of the interstitial diffuser. For Cd and Cu, because the defect state is the non-degenerated slike state under Td symmetry, the diffusions are almost along the [111] directions between the tetrahedral sites, although the diffusion of Cu shows some deviation due to the s - d coupling. The diffusions of the neutral and charged Cd and Cu follow similar paths. However, for Te and Cl atoms, because the defect state is the degenerated p-like state under Td symmetry, large distortions occur. Therefore, the diffusion paths are very different from those of Cd and Cu interstitials, and depend strongly on the charge states of the interstitial atoms. For Te, we find that the distortion is mostly stabilized by the crystal-field splitting, but for Cl, the exchange splitting plays a more important role.

  18. Correlation between the electronic structures and diffusion paths of interstitial defects in semiconductors: The case in CdTe

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Ma, Jie; Yang, Jihui; Da Silva, J. L.F.; Wei, Su-Huai

    2014-10-30

    Using first-principles calculations, we study the diffusions of interstitial defects Cd, Cu, Te, and Cl in CdTe. We find that the diffusion behavior is strongly correlated with the electronic structure of the interstitial diffuser. For Cd and Cu, because the defect state is the non-degenerated slike state under Td symmetry, the diffusions are almost along the [111] directions between the tetrahedral sites, although the diffusion of Cu shows some deviation due to the s - d coupling. The diffusions of the neutral and charged Cd and Cu follow similar paths. However, for Te and Cl atoms, because the defect statemore » is the degenerated p-like state under Td symmetry, large distortions occur. Therefore, the diffusion paths are very different from those of Cd and Cu interstitials, and depend strongly on the charge states of the interstitial atoms. For Te, we find that the distortion is mostly stabilized by the crystal-field splitting, but for Cl, the exchange splitting plays a more important role.« less

  19. Surprising stability of neutral interstitial hydrogen in diamond and cubic BN

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Lyons, J. L.; Van de Walle, C. G.

    2016-01-21

    We report that in virtually all semiconductors and insulators, hydrogen interstitials (Hi) act as negative-U centers, implying that hydrogen is never stable in the neutral charge state. Using hybrid density functional calculations, we find a different behavior for Hi in diamond and cubic BN. In diamond, Hi is a very strong positive-U center, and the H0icharge state is stable over a Fermi-level range of more than 2 eV. In cubic BN, a III-V compound similar to diamond, we also find positive-U behavior, though over a much smaller Fermi-level range. Finally, these results highlight the unique behavior of Hi in thesemore » covalent wide-band-gap semiconductors.« less

  20. Quality Assurance of Multifractionated Pelvic Interstitial Brachytherapy for Postoperative Recurrences of Cervical Cancers: A Prospective Study

    SciTech Connect (OSTI)

    Shukla, Pragya; Chopra, Supriya; Engineer, Reena; Mahantshetty, Umesh; Paul, Siji Nojin; Phurailatpam, Reena; SV, Jamema; Shrivastava, Shyam K.

    2012-03-15

    Purpose: To evaluate three-dimensional needle displacements during multifractionated interstitial brachytherapy (BT) for cervical cancers. Methods and Materials: Patients scheduled to undergo pelvic interstitial BT for postoperative and or postradiation vault recurrences were included from November 2009 to December 2010. All procedures were performed under spinal anesthesia. Postprocedure BT planning CT scans were obtained with patients in supine position with arms on the chest (interslice thickness of 3 mm). Thereafter, verification CT was repeated at every alternate fraction. Needle displacements were measured in reference to a relocatable bony point. The mean cranial, caudal, anteroposterior, and mediolateral displacements were recorded. Statistical significance of mean interfraction displacements was evaluated with Wilcoxon Test. Results: Twenty patients were included. Seventeen received boost BT (20 Gy/5 fractions/3 days) after external radiation, three received radical BT alone (36 Gy/9 fractions/5-8 days). An average of three scans (range, 2-3) were available per patient, and 357 needle displacements were analyzed. For the entire study cohort, the average of mean needle displacement was 2.5 mm (range, 0-7.4), 17.4 mm (range, 0-27.9), 1.7 mm (range, 0-6.7), 2.1 mm (range, 0-9.5), 1.7 mm (range, 0-9.3), and 0.6 mm (range, 0-7.8) in cranial, caudal, anterior, posterior, right, and left directions, respectively. The mean displacement in the caudal direction was higher between Days 1 and 2 than that between Days 2 and 3 (13.4 mm vs. 3.8 mm; p = 0.01). The average caudal displacements were no different between reirradiation and boost cohort (15.2 vs. 17.8 mm). Conclusions: Clinically significant caudal displacements occur during multifractionated pelvic brachytherapy. Optimal margins need to be incorporated while preplanning brachytherapy to account for interfraction displacements.

  1. Fermilab | Tritium at Fermilab | Ferry Creek Aerial View

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Ferry Creek Aerial View Ferry Creek Aerial View

  2. Fermilab | Tritium at Fermilab | Kress Creek Aerial View

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Kress Creek Aerial View Kress Creek Aerial View

  3. Highland View school | Y-12 National Security Complex

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Highland View school Highland View school Aerial showing Highland View school and surrounding homes

  4. Radiation View Factor With Shadowing

    Energy Science and Technology Software Center (OSTI)

    1992-02-24

    FACET calculates the radiation geometric view factor (alternatively called shape factor, angle factor, or configuration factor) between surfaces for axisymmetric, two-dimensional planar and three-dimensional geometries with interposed third surface obstructions. FACET was developed to calculate view factors as input data to finite element heat transfer analysis codes.

  5. TotalView Training 2015

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    TotalView Training 2015 TotalView Training 2015 NERSC will host an in-depth training course on TotalView, a graphical parallel debugger developed by Rogue Wave Software, on Thursday, March 26, 2015. This will be provided by Rogue Wave Software staff members. The training will include a lecture and demo sessions in the morning, followed by a hands-on parallel debugging session in the afternoon. Location This event will be presented online using WebEx technology and in person at NERSC Oakland

  6. Workshop on neutron capture therapy

    SciTech Connect (OSTI)

    Fairchild, R.G.; Bond, V.P.

    1986-01-01

    Potentially optimal conditions for Neutron Capture Therapy (NCT) may soon be in hand due to the anticipated development of band-pass filtered beams relatively free of fast neutron contaminations, and of broadly applicable biomolecules for boron transport such as porphyrins and monoclonal antibodies. Consequently, a number of groups in the US are now devoting their efforts to exploring NCT for clinical application. The purpose of this Workshop was to bring these groups together to exchange views on significant problems of mutual interest, and to assure a unified and effective approach to the solutions. Several areas of preclinical investigation were deemed to be necessary before it would be possible to initiate clinical studies. As neither the monomer nor the dimer of sulfhydryl boron hydride is unequivocally preferable at this time, studies on both compounds should be continued until one is proven superior.

  7. Wide field of view telescope

    DOE Patents [OSTI]

    Ackermann, Mark R.; McGraw, John T.; Zimmer, Peter C.

    2008-01-15

    A wide field of view telescope having two concave and two convex reflective surfaces, each with an aspheric surface contour, has a flat focal plane array. Each of the primary, secondary, tertiary, and quaternary reflective surfaces are rotationally symmetric about the optical axis. The combination of the reflective surfaces results in a wide field of view in the range of approximately 3.8.degree. to approximately 6.5.degree.. The length of the telescope along the optical axis is approximately equal to or less than the diameter of the largest of the reflective surfaces.

  8. Views of the solar system

    SciTech Connect (OSTI)

    Hamilton, C.

    1995-02-01

    Views of the Solar System has been created as an educational tour of the solar system. It contains images and information about the Sun, planets, moons, asteroids and comets found within the solar system. The image processing for many of the images was done by the author. This tour uses hypertext to allow space travel by simply clicking on a desired planet. This causes information and images about the planet to appear on screen. While on a planet page, hyperlinks travel to pages about the moons and other relevant available resources. Unusual terms are linked to and defined in the Glossary page. Statistical information of the planets and satellites can be browsed through lists sorted by name, radius and distance. History of Space Exploration contains information about rocket history, early astronauts, space missions, spacecraft and detailed chronology tables of space exploration. The Table of Contents page has links to all of the various pages within Views Of the Solar System.

  9. For current viewing resistor loads

    DOE Patents [OSTI]

    Lyons, Gregory R.; Hass, Jay B.

    2011-04-19

    The invention comprises a terminal unit for a flat cable comprising a BNC-PCB connector having a pin for electrically contacting one or more conducting elements of a flat cable, and a current viewing resistor having an opening through which the pin extends and having a resistor face that abuts a connector face of the BNC-PCB connector, wherein the device is a terminal unit for the flat cable.

  10. Comparison of precipitate behaviors in ultra-low carbon, titanium-stabilized interstitial free steel sheets under different annealing processes

    SciTech Connect (OSTI)

    Shi, J.; Wang, X.

    1999-12-01

    Ultra-low carbon, titanium-stabilized interstitial free (ULC Ti-IF) steel sheets are widely used in the automobile industry because of excellent deep drawability. The annealing process is critical to their final property, and there are two different annealing processes used in industrial production of interstitial free (IF) steel sheets, namely batch annealing and continuous annealing. In this study, precipitation behaviors of titanium IF steels, that is, TiN, TiS, Ti{sub 4}(CS){sub 2}, and TiC, the size and dispersion of TiN, TiS, and Ti{sub 4}(CS){sub 2} remained almost unchanged after either annealing process. Conversely, the average size of a TiC particle increased substantially after both annealing processes, while TiC after continuous annealing was larger than that after batch annealing due to the higher heating temperature of continuous annealing. Two new particles, FeTiP and (Ti, Mn)S, were also observed in the batch annealing process but not in continuous annealing. The structure of FeTiP and (Ti, Mn)S were studied, and furthermore the evolution of FeTiP precipitation was found to be closely related to recrystallization in batch annealing. Finally, the interrelation among processing parameters, precipitation behaviors, and final property was studied.

  11. Accelerators for Cancer Therapy

    DOE R&D Accomplishments [OSTI]

    Lennox, Arlene J.

    2000-05-30

    The vast majority of radiation treatments for cancerous tumors are given using electron linacs that provide both electrons and photons at several energies. Design and construction of these linacs are based on mature technology that is rapidly becoming more and more standardized and sophisticated. The use of hadrons such as neutrons, protons, alphas, or carbon, oxygen and neon ions is relatively new. Accelerators for hadron therapy are far from standardized, but the use of hadron therapy as an alternative to conventional radiation has led to significant improvements and refinements in conventional treatment techniques. This paper presents the rationale for radiation therapy, describes the accelerators used in conventional and hadron therapy, and outlines the issues that must still be resolved in the emerging field of hadron therapy.

  12. Better Buildings Network View | March 2014

    Broader source: Energy.gov [DOE]

    The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network.

  13. Better Buildings Network View | January 2015

    Broader source: Energy.gov [DOE]

    The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network.

  14. Better Buildings Network View | June 2015

    Broader source: Energy.gov [DOE]

    The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network.

  15. Better Buildings Network View | May 2014

    Broader source: Energy.gov [DOE]

    The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network.

  16. The Better Buildings Neighborhood View-- July 2012

    Broader source: Energy.gov [DOE]

    The Better Buildings Neighborhood View monthly newsletter from the U.S. Department of Energy's Better Buildings Neighborhood Program.

  17. The Better Buildings Neighborhood View-- Fall 2011

    Broader source: Energy.gov [DOE]

    Better Buildings Neighborhood View, from the Better Buildings Neighborhood Program of the U.S. Department of Energy.

  18. View Shed - Version 1.0

    Energy Science and Technology Software Center (OSTI)

    2014-09-18

    The View Shed library is a collection of Umbra modules that are used to calculate areas of visual coverage (view sheds). It maps high and low visibility areas and calculates sensor (camera placement for maximum coverage and performance. This assertion includes a managed C++ wrapper code (ViewShedWrapper) to enable C# applications, such as OpShed, to incorporate this library.

  19. Simulation of xenon, uranium vacancy and interstitial diffusion and grain boundary segregation in UO2

    SciTech Connect (OSTI)

    Andersson, Anders D.; Tonks, Michael R.; Casillas, Luis; Nerikar, Pankaj; Vyas, Shyam; Uberuaga, Blas P.; Stanek, Christopher R.

    2014-10-31

    In light water reactor fuel, gaseous fission products segregate to grain boundaries, resulting in the nucleation and growth of large intergranular fission gas bubbles. Based on the mechanisms established from density functional theory (DFT) and empirical potential calculations 1, continuum models for diffusion of xenon (Xe), uranium (U) vacancies and U interstitials in UO2 have been derived for both intrinsic conditions and under irradiation. Segregation of Xe to grain boundaries is described by combining the bulk diffusion model with a model for the interaction between Xe atoms and three different grain boundaries in UO2 ( ?5 tilt, ?5 twist and a high angle random boundary),as derived from atomistic calculations. All models are implemented in the MARMOT phase field code, which is used to calculate effective Xe and U diffusivities as well as redistribution for a few simple microstructures.

  20. In-Situ Characterization of Cloud Condensation Nuclei, Interstitial, and background Particles using Single Particle Mass Spectrometer, SPLAT II

    SciTech Connect (OSTI)

    Zelenyuk, Alla; Imre, D.; Earle, Michael; Easter, Richard C.; Korolev, Alexei; Leaitch, W. R.; Liu, Peter; Macdonald, A. M.; Ovchinnikov, Mikhail; Strapp, Walter

    2010-10-01

    Aerosol indirect effect remains the most uncertain aspect of climate change modeling because proper test requires knowledge of individual particles sizes and compositions with high spatial and temporal resolution. We present the first deployment of a single particle mass spectrometer (SPLAT II) that is operated in a dual data acquisition mode to measure all the required individual particle properties with sufficient temporal resolution to definitively resolve the aerosol-cloud interaction in this exemplary case. We measured particle number concentrations, asphericity, and individual particle size, composition, and density with better than 60 seconds resolution. SPLAT II measured particle number concentrations between 70 particles cm-3and 300 particles cm-3, an average particle density of 1.4 g cm-3. Found that most particles are composed of oxygenated organics, many of which are mixed with sulfates. Biomass burn particles some with sulfates were prevalent, particularly at higher altitudes, and processed sea-salt was observed over the ocean. Analysis of cloud residuals shows that with time cloud droplets acquire sulfate by the reaction of peroxide with SO2. Based on the particle mass spectra and densities we find that the compositions of cloud condensation nuclei are similar to those of background aerosol but, contain on average ~7% more sulfate, and do not include dust and metallic particles. A comparison between the size distributions of background, activated, and interstitial particles shows that while nearly none of the activated particles is smaller than 115 nm, more than 80% of interstitial particles are smaller than 115 nm. We conclude that for this cloud the most important difference between CCN and background aerosol is particle size although having more sulfate also helps.

  1. The BetterBuildings View | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    The BetterBuildings View The BetterBuildings View The BetterBuildings View Newsletter, April 2011, from the U.S. Department of Energy's Better Buildings Neighborhood Program. PDF icon The BetterBuildings View April 2011 More Documents & Publications The Better Buildings Neighborhood View - October 2012 The Better Buildings Neighborhood View -- Fall 2011 The Better Buildings Neighborhood View -- April 2013

  2. Prairie View Gas Recovery Biomass Facility | Open Energy Information

    Open Energy Info (EERE)

    View Gas Recovery Biomass Facility Jump to: navigation, search Name Prairie View Gas Recovery Biomass Facility Facility Prairie View Gas Recovery Sector Biomass Facility Type...

  3. Better Buildings Network View | September 2015 | Department of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Better Buildings Network View | September 2015 Better Buildings Network View | September 2015 The Better Buildings Network View monthly newsletter from the U.S. Department of...

  4. Better Buildings Network View, April 2015

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... systems Better Buildings Network View financial sector. ... Sunnovations, Inc., is a McLean, Virginia-based firm offering ... as featured in the new Resource Corner Designing ...

  5. High Performance Builder Spotlight: Clifton View Homes

    SciTech Connect (OSTI)

    2011-01-01

    Clifton View Homes’s remodel of a 1962 rambler, on Whidbey Island in Washington State, cut energy costs by two-thirds.

  6. Better Buildings Network View, May 2015

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... now Leveraging Seasonal Opportunities for Marketing Better Buildings Network View making. ... Prize (GUEP) participants are going digital to encourage people across the United ...

  7. The Better Buildings Neighborhood View-- July 2013

    Broader source: Energy.gov [DOE]

    The Better Buildings Neighborhood View monthly newsletter from the U.S. Department of Energy's Better Buildings Neighborhood Program - July 2013.

  8. The Better Buildings Neighborhood View -- April 2012 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    2 The Better Buildings Neighborhood View -- April 2012 The Better Buildings Neighborhood View monthly newsletter from the U.S. Department of Energy's Better Buildings Neighborhood Program. PDF icon BB Neighborhood View -- April 2012 More Documents & Publications The Better Buildings Neighborhood View -- March 2012 The Better Buildings Neighborhood View - September 2012 The Better Buildings Neighborhood View -- July 2012

  9. The Better Buildings Neighborhood View -- April 2013 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    3 The Better Buildings Neighborhood View -- April 2013 The Better Buildings Neighborhood View monthly newsletter from the U.S. Department of Energy's Better Buildings Neighborhood Program - April 2013. PDF icon BB Neighborhood View -- April 2013 More Documents & Publications The Better Buildings Neighborhood View -- July 2013 The Better Buildings Neighborhood View -- January 2013 The Better Buildings Neighborhood View -- December 2013

  10. The Better Buildings Neighborhood View -- August 2012 | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy August 2012 The Better Buildings Neighborhood View -- August 2012 The Better Buildings Neighborhood View monthly newsletter from the U.S. Department of Energy's Better Buildings Neighborhood Program. PDF icon BB Neighborhood View -- August 2012 More Documents & Publications The Better Buildings Neighborhood View - September 2012 The Better Buildings Neighborhood View -- July 2012 The Better Buildings Neighborhood View -- June 2012

  11. The Better Buildings Neighborhood View -- January 2012 | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy 2 The Better Buildings Neighborhood View -- January 2012 The Better Buildings Neighborhood View monthly newsletter from the U.S. Department of Energy's Better Buildings Neighborhood Program. PDF icon BB Neighborhood View -- January 2012 More Documents & Publications The Better Buildings Neighborhood View -- March 2012 The Better Buildings Neighborhood View -- February 2012 The BetterBuildings View

  12. The Better Buildings Neighborhood View -- June 2012 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    June 2012 The Better Buildings Neighborhood View -- June 2012 The Better Buildings Neighborhood View monthly newsletter from the U.S. Department of Energy's Better Buildings Neighborhood Program. PDF icon BB Neighborhood View -- June 2012 More Documents & Publications The Better Buildings Neighborhood View -- August 2012 The Better Buildings Neighborhood View - October 2012 The Better Buildings Neighborhood View -- April 2012

  13. Better Buildings Network View | April 2015 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    5 Better Buildings Network View | April 2015 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF icon Better Buildings Network View April 2015 More Documents & Publications Better Buildings Network View | May 2015 Better Buildings Network View | March 2015 Better Buildings Network View | July-August

  14. Better Buildings Network View | April 2016 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    6 Better Buildings Network View | April 2016 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF icon Better Buildings Network View April 2016 More Documents & Publications Better Buildings Network View | March 2016 Better Buildings Network View | January 2016 Better Buildings Network View | February 2016

  15. Better Buildings Network View | February 2014 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    4 Better Buildings Network View | February 2014 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF icon Better Buildings Network View February 2014 More Documents & Publications Better Buildings Network View | January 2014 Better Buildings Network View | May 2015 Better Buildings Network View | June 2015

  16. Better Buildings Network View | February 2016 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    6 Better Buildings Network View | February 2016 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF icon Better Buildings Network View February 2016 More Documents & Publications Better Buildings Network View | March 2016 Better Buildings Network View | June 2014 Better Buildings Network View | April 2016

  17. Better Buildings Network View | January 2014 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    4 Better Buildings Network View | January 2014 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF icon Better Buildings Network View January 2014 More Documents & Publications Better Buildings Network View | February 2015 Better Buildings Network View | May 2015 Better Buildings Network View | September 2014

  18. Better Buildings Network View | January 2016 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    6 Better Buildings Network View | January 2016 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF icon Better Buildings Network View January 2016 More Documents & Publications Better Buildings Network View | October 2015 Better Buildings Network View | April 2016 Better Buildings Network View | December

  19. Better Buildings Network View | June 2014 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    4 Better Buildings Network View | June 2014 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF icon Better Buildings Network View June 2014 More Documents & Publications Better Buildings Network View | June 2015 Better Buildings Network View | July-August 2014 Better Buildings Network View | April 2014

  20. Better Buildings Network View | March 2015 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    5 Better Buildings Network View | March 2015 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF icon Better Buildings Network View March 2015 More Documents & Publications Better Buildings Network View | January 2015 Better Buildings Network View | December 2014 Better Buildings Network View | April 2015

  1. Better Buildings Network View | March 2016 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    6 Better Buildings Network View | March 2016 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF icon Better Buildings Network View March 2016 More Documents & Publications Better Buildings Network View | April 2016 Better Buildings Network View | February 2016 Better Buildings Network View | January 2016

  2. Better Buildings Network View | October 2015 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    5 Better Buildings Network View | October 2015 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF icon Better Buildings Network View October 2015 More Documents & Publications Better Buildings Network View | January 2016 Better Buildings Network View | April 2016 Better Buildings Network View | November

  3. The Better Buildings Neighborhood View - October 2012 | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy The Better Buildings Neighborhood View - October 2012 The Better Buildings Neighborhood View - October 2012 The Better Buildings Neighborhood View monthly newsletter from the U.S. Department of Energy's Better Buildings Neighborhood Program - October 2012 PDF icon bb_view_october2012.pdf More Documents & Publications The Better Buildings Neighborhood View -- July 2013 The Better Buildings Neighborhood View -- Fall 2011 The Better Buildings Neighborhood View -- December 2013

  4. A common-view disciplined oscillator

    SciTech Connect (OSTI)

    Lombardi, Michael A.; Dahlen, Aaron P.

    2010-05-15

    This paper describes a common-view disciplined oscillator (CVDO) that locks to a reference time scale through the use of common-view global positioning system (GPS) satellite measurements. The CVDO employs a proportional-integral-derivative controller that obtains near real-time common-view GPS measurements from the internet and provides steering corrections to a local oscillator. A CVDO can be locked to any time scale that makes real-time common-view data available and can serve as a high-accuracy, self-calibrating frequency and time standard. Measurement results are presented where a CVDO is locked to UTC(NIST), the coordinated universal time scale maintained at the National Institute of Standards and Technology in Boulder, Colorado.

  5. TotalView Parallel Debugger at NERSC

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The performance of the GUI can be greatly improved if used in conjunction with free NX software. The TotalView documentation web page is a good resource for learning more...

  6. JOBAID-VIEWING AN EMPLOYEE MATRIX (SUPERVISOR)

    Broader source: Energy.gov [DOE]

    The purpose of this job aid is to guide supervisor users through the step-by-step process of viewing an employee matrix within SuccessFactors Learning.

  7. The Better Buildings Neighborhood View - Summer 2011 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Summer 2011 The Better Buildings Neighborhood View - Summer 2011 The quarterly update newsletter of the Better Buildings program of the U.S. Department of Energy. PDF icon BB Neighborhood View -- Summer 2011 More Documents & Publications The Better Buildings Neighborhood View -- January 2012 The Better Buildings Neighborhood View -- March 2012 The Better Buildings Neighborhood View -- May

  8. The Better Buildings Neighborhood View -- March 2012 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    March 2012 The Better Buildings Neighborhood View -- March 2012 The Better Buildings Neighborhood View monthly newsletter from the U.S. Department of Energy's Better Buildings Neighborhood Program PDF icon BB Neighborhood View -- March 2012 More Documents & Publications The Better Buildings Neighborhood View -- February 2012 The Better Buildings Neighborhood View -- January 2012 Commercial Buildings Integration Program Overview - 2015 BTO Peer Review

  9. The Better Buildings Neighborhood View -- May 2012 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    - May 2012 The Better Buildings Neighborhood View -- May 2012 The Better Buildings Neighborhood View monthly newsletter from the U.S. Department of Energy's Better Buildings Neighborhood Program PDF icon BB Neighborhood View -- May 2012 More Documents & Publications The Better Buildings Neighborhood View -- June 2012 The Better Buildings Neighborhood View - September 2012

  10. Better Buildings Network View | April 2014 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    4 Better Buildings Network View | April 2014 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF icon Better Buildings Network View April 2014 More Documents & Publications Better Buildings Network View | December 2014 Better Buildings Residential Network Orientation Webinar Better Buildings Network View | May

  11. Better Buildings Network View | December 2014 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    4 Better Buildings Network View | December 2014 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF icon Better Buildings Network View December 2014 More Documents & Publications Better Buildings Network View | February 2014 Better Buildings Network View | November 2014 Lessons Learned: Peer Exchange Calls -- No. 3

  12. Better Buildings Network View | February 2015 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    5 Better Buildings Network View | February 2015 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF icon Better Buildings Network View February 2015 More Documents & Publications Better Buildings Network View | June 2015 Nothing But Networking for Residential Network Members Better Buildings Network View | November 2014

  13. Better Buildings Network View | May 2015 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    5 Better Buildings Network View | May 2015 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF icon Better Buildings Network View May 2015 More Documents & Publications Better Buildings Network View | June 2015 Home Performance with ENERGY STAR - 2014 BTO Peer Review Better Buildings Network View | April 2015

  14. Better Buildings Network View | November 2014 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    4 Better Buildings Network View | November 2014 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF icon Better Buildings Network View November 2014 More Documents & Publications Better Buildings Network View | July-August 2014 Better Buildings Residential Network Orientation Webinar Better Buildings Network View | December 2014

  15. Better Buildings Network View | October 2014 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    October 2014 Better Buildings Network View | October 2014 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF icon Better Buildings Network View October 2014 More Documents & Publications Better Buildings Network View | September 2014 Better Buildings Network View | December 2014

  16. Neutron capture therapies

    DOE Patents [OSTI]

    Yanch, Jacquelyn C.; Shefer, Ruth E.; Klinkowstein, Robert E.

    1999-01-01

    In one embodiment there is provided an application of the .sup.10 B(n,.alpha.).sup.7 Li nuclear reaction or other neutron capture reactions for the treatment of rheumatoid arthritis. This application, called Boron Neutron Capture Synovectomy (BNCS), requires substantially altered demands on neutron beam design than for instance treatment of deep seated tumors. Considerations for neutron beam design for the treatment of arthritic joints via BNCS are provided for, and comparisons with the design requirements for Boron Neutron Capture Therapy (BNCT) of tumors are made. In addition, exemplary moderator/reflector assemblies are provided which produce intense, high-quality neutron beams based on (p,n) accelerator-based reactions. In another embodiment there is provided the use of deuteron-based charged particle reactions to be used as sources for epithermal or thermal neutron beams for neutron capture therapies. Many d,n reactions (e.g. using deuterium, tritium or beryllium targets) are very prolific at relatively low deuteron energies.

  17. City of Mountain View, Missouri (Utility Company) | Open Energy...

    Open Energy Info (EERE)

    View Place: Missouri Phone Number: (417) 934-2601 Website: mountainviewmo.comindex.phpg Facebook: https:www.facebook.comCityOfMountainViewMissouri Outage Hotline: (877)...

  18. Mountain View Power Partners II Wind Farm | Open Energy Information

    Open Energy Info (EERE)

    II Wind Farm Jump to: navigation, search Name Mountain View Power Partners II Wind Farm Facility Mountain View Power Partners II Sector Wind energy Facility Type Commercial Scale...

  19. Mountain View Power Partners III Wind Farm | Open Energy Information

    Open Energy Info (EERE)

    III Wind Farm Jump to: navigation, search Name Mountain View Power Partners III Wind Farm Facility Mountain View Power Partners III Sector Wind energy Facility Type Commercial...

  20. OpenEI:Neutral point of view | Open Energy Information

    Open Energy Info (EERE)

    point of view Jump to: navigation, search Neutral point of view (NPOV) means that articles and content contributed or edited on the platform must be unbiased. All significant...

  1. The Better Buildings Neighborhood View -- January 2013 | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    3 The Better Buildings Neighborhood View -- January 2013 The Better Buildings Neighborhood View monthly newsletter from the U.S. Department of Energy's Better Buildings...

  2. Better Buildings Network View | September 2014 | Department of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    September 2014 Better Buildings Network View | September 2014 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential...

  3. The Better Buildings Neighborhood View -- July 2013 | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    3 The Better Buildings Neighborhood View -- July 2013 The Better Buildings Neighborhood View monthly newsletter from the U.S. Department of Energy's Better Buildings Neighborhood...

  4. The Better Buildings Neighborhood View -- April 2013 | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    3 The Better Buildings Neighborhood View -- April 2013 The Better Buildings Neighborhood View monthly newsletter from the U.S. Department of Energy's Better Buildings Neighborhood...

  5. The Better Buildings Neighborhood View -- April 2012 | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    2 The Better Buildings Neighborhood View -- April 2012 The Better Buildings Neighborhood View monthly newsletter from the U.S. Department of Energy's Better Buildings Neighborhood...

  6. The Better Buildings Neighborhood View -- August 2012 | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    August 2012 The Better Buildings Neighborhood View -- August 2012 The Better Buildings Neighborhood View monthly newsletter from the U.S. Department of Energy's Better Buildings...

  7. Better Buildings Network View | November 2015 | Department of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    5 Better Buildings Network View | November 2015 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF...

  8. The Better Buildings Neighborhood View -- March 2012 | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    March 2012 The Better Buildings Neighborhood View -- March 2012 The Better Buildings Neighborhood View monthly newsletter from the U.S. Department of Energy's Better Buildings...

  9. The Better Buildings Neighborhood View -- June 2012 | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    June 2012 The Better Buildings Neighborhood View -- June 2012 The Better Buildings Neighborhood View monthly newsletter from the U.S. Department of Energy's Better Buildings...

  10. The Better Buildings Neighborhood View -- July 2012 | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    2 The Better Buildings Neighborhood View -- July 2012 The Better Buildings Neighborhood View monthly newsletter from the U.S. Department of Energy's Better Buildings Neighborhood...

  11. The Better Buildings Neighborhood View -- January 2012 | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    2 The Better Buildings Neighborhood View -- January 2012 The Better Buildings Neighborhood View monthly newsletter from the U.S. Department of Energy's Better Buildings...

  12. The Better Buildings Neighborhood View -- May 2012 | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    - May 2012 The Better Buildings Neighborhood View -- May 2012 The Better Buildings Neighborhood View monthly newsletter from the U.S. Department of Energy's Better Buildings...

  13. The Better Buildings Neighborhood View -- Fall 2011 | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Fall 2011 The Better Buildings Neighborhood View -- Fall 2011 Better Buildings Neighborhood View, from the Better Buildings Neighborhood Program of the U.S. Department of Energy....

  14. Better Buildings Network View | April 2014 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    4 Better Buildings Network View | April 2014 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF ...

  15. Better Buildings Network View | January 2016 | Department of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    6 Better Buildings Network View | January 2016 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF ...

  16. Better Buildings Network View | February 2015 | Department of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    5 Better Buildings Network View | February 2015 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF ...

  17. Better Buildings Network View | December 2015 | Department of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    5 Better Buildings Network View | December 2015 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF ...

  18. Better Buildings Network View | June 2014 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    4 Better Buildings Network View | June 2014 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF icon ...

  19. Better Buildings Network View | October 2014 | Department of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    October 2014 Better Buildings Network View | October 2014 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential ...

  20. Better Buildings Network View | January 2015 | Department of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    5 Better Buildings Network View | January 2015 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF ...

  1. Better Buildings Network View | May 2015 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    5 Better Buildings Network View | May 2015 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF icon ...

  2. Better Buildings Network View | February 2014 | Department of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    4 Better Buildings Network View | February 2014 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF ...

  3. Better Buildings Network View | November 2014 | Department of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    4 Better Buildings Network View | November 2014 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF ...

  4. Better Buildings Network View | July-August 2014 | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    4 Better Buildings Network View | July-August 2014 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. ...

  5. Better Buildings Network View | February 2016 | Department of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    6 Better Buildings Network View | February 2016 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF ...

  6. Better Buildings Network View | May 2014 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    4 Better Buildings Network View | May 2014 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF icon ...

  7. Better Buildings Network View | March 2014 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    4 Better Buildings Network View | March 2014 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF ...

  8. Better Buildings Network View | April 2015 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    5 Better Buildings Network View | April 2015 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF ...

  9. Better Buildings Network View | December 2014 | Department of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    4 Better Buildings Network View | December 2014 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF ...

  10. Better Buildings Network View | March 2015 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    5 Better Buildings Network View | March 2015 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF ...

  11. Better Buildings Network View | January 2014 | Department of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    4 Better Buildings Network View | January 2014 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF ...

  12. Better Buildings Network View | October 2015 | Department of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    5 Better Buildings Network View | October 2015 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF ...

  13. Better Buildings Network View | March 2016 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    6 Better Buildings Network View | March 2016 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF ...

  14. Better Buildings Network View | June 2015 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    5 Better Buildings Network View | June 2015 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF icon ...

  15. Better Buildings Network View | July-August 2015 | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    5 Better Buildings Network View | July-August 2015 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. ...

  16. Residential Windows and Window Coverings: A Detailed View of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Residential Windows and Window Coverings: A Detailed View of the Installed Base and User Behavior Residential Windows and Window Coverings: A Detailed View of the Installed Base ...

  17. WE-G-17A-05: Real-Time Catheter Localization Using An Active MR Tracker for Interstitial Brachytherapy

    SciTech Connect (OSTI)

    Wang, W; Damato, A; Viswanathan, A; Cormack, R; Penzkofer, T; Schmidt, E; Pan, L; Gilson, W; Seethamraju, R

    2014-06-15

    Purpose: To develop a novel active MR-tracking system which can provide accurate and rapid localization of brachytherapy catheters, and assess its reliability and spatial accuracy in comparison to standard catheter digitization using MR images. Methods: An active MR tracker for brachytherapy was constructed by adding three printed-circuit micro-coils to the shaft of a commercial metallic stylet. A gel phantom with an embedded framework was built, into which fifteen 14-Gauge catheters were placed, following either with parallel or crossed paths. The tracker was inserted sequentially into each catheter, with MR-tracking running continuously. Tracking was also performed during the tracker's removal from each catheter. Catheter trajectories measured from the insertion and the removal procedures using the same micro-coil were compared, as well as trajectories obtained using different micro-coils. A 3D high-resolution MR image dataset of the phantom was acquired and imported into a treatment planning system (TPS) for catheter digitization. A comparison between MR-tracked positions and positions digitized from MR images by TPS was performed. Results: The MR tracking shows good consistency for varying catheter paths and for all micro-coils (mean difference ∼1.1 mm). The average distance between the MR-tracking trajectory and catheter digitization from the MR images was 1.1 mm. Ambiguity in catheter assignment from images due to crossed paths was resolved by active tracking. When tracking was interleaved with imaging, real-time images were continuously acquired at the instantaneous tip positions and displayed on an external workstation. Conclusion: The active MR tracker may be used to provide an independent measurement of catheter location in the MR environment, potentially eliminating the need for subsequent CT. It may also be used to control realtime imaging of catheter placement. This will enable MR-based brachytherapy planning of interstitial implants without ionizing radiation, with the potential to enable dosimetric guidance of catheter placement. We gratefully acknowledge support from the American Heart Association SDG 10SDG2610139, NIH 1R21CA158987-01A1, U41-RR019703, and R21 CA 167800, as well as a BWH Department of Radiation Oncology post-doctoral fellowship support. Li Pan and Wesley Gilson are employees of Siemens Corporation, Corporate Technology. Ravi Seethamraju is an employee of Siemens Healthcare.

  18. Our view: Vaccinate now, prevent flu later

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Our view: Vaccinate now, prevent flu later Our view: Vaccinate now, prevent flu later Los Alamos National Laboratory scientists are predicting that this winter's flu season is most likely to peak in February across much of the United States. The scientists can say this because of the model they have constructed. December 24, 2015 Man sneezing Model suggests still time to get your flu shot and be protected. "There's no crystal ball when it comes to predicting disease outbreaks," said

  19. Linked-View Parallel Coordinate Plot Renderer

    Energy Science and Technology Software Center (OSTI)

    2011-06-28

    This software allows multiple linked views for interactive querying via map-based data selection, bar chart analytic overlays, and high dynamic range (HDR) line renderings. The major component of the visualization package is a parallel coordinate renderer with binning, curved layouts, shader-based rendering, and other techniques to allow interactive visualization of multidimensional data.

  20. The Better Buildings Neighborhood View - September 2012 | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy September 2012 The Better Buildings Neighborhood View - September 2012 Monthly newsletter from the U.S. Department of Energy's Better Buildings Neighborhood Program. PDF icon BB Neighborhood View -- September 2012 More Documents & Publications The Better Buildings Neighborhood View -- Fall 2011 The Better Buildings Neighborhood View -- July 2013

  1. Better Buildings Network View | December 2015 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    5 Better Buildings Network View | December 2015 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF icon Better Buildings Network View December 2015 More Documents & Publications BBRN Factsheet: Case Study: Community Engagement Better Buildings Network View | July-August 2015 Better Buildings Residential Network Orientation Webinar

  2. Better Buildings Network View | September 2015 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Network View | September 2015 Better Buildings Network View | September 2015 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF icon Better Buildings Network View September 2015 More Documents & Publications TTWG Licensing Guide ITP Aluminum: Technical Working Group on Inert Anode Technologies EIS-0333: Draft Environmental Impact Statement

  3. Recombination radius of a Frenkel pair and capture radius of a self-interstitial atom by vacancy clusters in bcc Fe

    SciTech Connect (OSTI)

    Nakashima, Kenichi; Stoller, Roger E.; Xu, Haixuan

    2015-08-04

    The recombination radius of a Frenkel pair is a fundamental parameter for the object kinetic Monte Carlo (OKMC) and mean field rate theory (RT) methods that are used to investigate irradiation damage accumulation in neutron irradiated nuclear materials. The recombination radius in bcc Fe has been studied both experimentally and numerically, however there is no general consensus about its value. The detailed atomistic processes of recombination also remain uncertain. Values from 1:0a? to 3:3a? have been employed as a recombination radius in previous studies using OKMC and RT. The recombination process of a Frenkel pair is investigated at the atomic level using the self-evolved atomistic kinetic Monte Carlo (SEAKMC) method in this paper. SEAKMC calculations reveal that a self-interstitial atom recombines with a vacancy in a spontaneous reaction from several nearby sites following characteristic pathways. The recombination radius of a Frenkel pair is estimated to be 2.26a? by taking the average of the recombination distances from 80 simulation cases. This value agrees well with the experimental estimate. In addition, we apply these procedures to the capture radius of a self-interstitial atom by a vacancy cluster. The capture radius is found to gradually increase with the size of the vacancy cluster. The fitting curve for the capture radius is obtained as a function of the number of vacancies in the cluster.

  4. Recombination radius of a Frenkel pair and capture radius of a self-interstitial atom by vacancy clusters in bcc Fe

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Nakashima, Kenichi; Stoller, Roger E.; Xu, Haixuan

    2015-01-01

    The recombination radius of a Frenkel pair is a fundamental parameter for the object kinetic Monte Carlo (OKMC) and mean field rate theory (RT) methods that are used to investigate irradiation damage accumulation in neutron irradiated nuclear materials. The recombination radius in bcc Fe has been studied both experimentally and numerically, however there is no general consensus about its value. The detailed atomistic processes of recombination also remain uncertain. Values from 1:0a₀ to 3:3a₀ have been employed as a recombination radius in previous studies using OKMC and RT. The recombination process of a Frenkel pair is investigated at the atomicmore » level using the self-evolved atomistic kinetic Monte Carlo (SEAKMC) method in this paper. SEAKMC calculations reveal that a self-interstitial atom recombines with a vacancy in a spontaneous reaction from several nearby sites following characteristic pathways. The recombination radius of a Frenkel pair is estimated to be 2.26a₀ by taking the average of the recombination distances from 80 simulation cases. This value agrees well with the experimental estimate. In addition, we apply these procedures to the capture radius of a self-interstitial atom by a vacancy cluster. The capture radius is found to gradually increase with the size of the vacancy cluster. The fitting curve for the capture radius is obtained as a function of the number of vacancies in the cluster.« less

  5. The Better Buildings Neighborhood View -- December 2013 | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy December 2013 The Better Buildings Neighborhood View -- December 2013 The Better Buildings Neighborhood View monthly newsletter from the U.S. Department of Energy's Better Buildings Neighborhood Program. PDF icon BB Neighborhood View -- December 2013 More Documents & Publications The Better Buildings Neighborhood View -- July 2013 Focus Series: Philadelphia Energyworks: In the City of Brotherly Love, Sharing Know-How Leads to Sustainability The Better Buildings Neighborhood View

  6. The Better Buildings Neighborhood View -- February 2012 | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy February 2012 The Better Buildings Neighborhood View -- February 2012 The Better Buildings Neighborhood View monthly newsletter from the U.S. Department of Energy's Better Buildings Neighborhood Program. PDF icon BB Neighborhood View -- February 2012 More Documents & Publications The Better Buildings Neighborhood View -- March 2012 The Better Buildings Neighborhood View -- January 2012 Microsoft Word - T4_VEIC_TO2_ Sub3_Residential Retrofit Program Design Guide Play Book_TEAM 4

  7. The Better Buildings Neighborhood View -- January 2013 | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy 3 The Better Buildings Neighborhood View -- January 2013 The Better Buildings Neighborhood View monthly newsletter from the U.S. Department of Energy's Better Buildings Neighborhood Program -- January 2013. PDF icon BB Neighborhood View -- January 2013 More Documents & Publications The Better Buildings Neighborhood View - September 2012 The Better Buildings Neighborhood View - October 2012 It's Academic: BetterBuildings for Michigan Partners With University to Reach Employees

  8. A Prospective Longitudinal Clinical Trial Evaluating Quality of Life After Breast-Conserving Surgery and High-Dose-Rate Interstitial Brachytherapy for Early-Stage Breast Cancer

    SciTech Connect (OSTI)

    Garsa, Adam A.; Ferraro, Daniel J.; DeWees, Todd A.; Deshields, Teresa L.; Margenthaler, Julie A.; Cyr, Amy E.; Naughton, Michael; Aft, Rebecca; Gillanders, William E.; Eberlein, Timothy; Matesa, Melissa A.; Ochoa, Laura L.; Zoberi, Imran

    2013-12-01

    Purpose: To prospectively examine quality of life (QOL) of patients with early stage breast cancer treated with accelerated partial breast irradiation (APBI) using high-dose-rate (HDR) interstitial brachytherapy. Methods and Materials: Between March 2004 and December 2008, 151 patients with early stage breast cancer were enrolled in a phase 2 prospective clinical trial. Eligible patients included those with Tis-T2 tumors measuring ?3 cm excised with negative surgical margins and with no nodal involvement. Patients received 3.4 Gy twice daily to a total dose of 34 Gy. QOL was measured using European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30, version 3.0, and QLQ-BR23 questionnaires. The QLQ-C30 and QLQ-BR23 questionnaires were evaluated during pretreatment and then at 6 to 8 weeks, 3 to 4 months, 6 to 8 months, and 1 and 2 years after treatment. Results: The median follow-up was 55 months. Breast symptom scores remained stable in the months after treatment, and they significantly improved 6 to 8 months after treatment. Scores for emotional functioning, social functioning, and future perspective showed significant improvement 2 years after treatment. Symptomatic fat necrosis was associated with several changes in QOL, including increased pain, breast symptoms, systemic treatment side effects, dyspnea, and fatigue, as well as decreased role functioning, emotional functioning, and social functioning. Conclusions: HDR multicatheter interstitial brachytherapy was well tolerated, with no significant detrimental effect on measured QOL scales/items through 2 years of follow-up. Compared to pretreatment scores, there was improvement in breast symptoms, emotional functioning, social functioning, and future perspective 2 years after treatment.

  9. The Better Buildings Neighborhood View -- February 2012 | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    View -- March 2012 The Better Buildings Neighborhood View -- January 2012 Microsoft Word - T4VEICTO2 Sub3Residential Retrofit Program Design Guide Play BookTEAM 4 FINAL.docx

  10. ParaView Red Blood Cell Tutorial | Argonne Leadership Computing...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ParaView Red Blood Cell Tutorial Goals This tutorial is intended to be a hands-on resource ... Data set for ParaView Red Blood Cell Tutorial File Open Icon Load Multi-component Dataset ...

  11. ALS Technique Gives Novel View of Lithium Battery Dendrite Growth

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ALS Technique Gives Novel View of Lithium Battery Dendrite Growth ALS Technique Gives Novel View of Lithium Battery Dendrite Growth Print Thursday, 24 April 2014 09:46 Lithium-ion ...

  12. New Window Technology Saves Energy and the View | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    New Window Technology Saves Energy and the View New Window Technology Saves Energy and the View November 5, 2013 - 3:55pm Addthis Researchers at the Energy Department's National...

  13. Mountain View Power Partners I Wind Farm | Open Energy Information

    Open Energy Info (EERE)

    I Wind Farm Jump to: navigation, search Name Mountain View Power Partners I Wind Farm Facility Mountain View Power Partners I Sector Wind energy Facility Type Commercial Scale Wind...

  14. Better Buildings Network View | September 2014 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    September 2014 Better Buildings Network View | September 2014 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF icon Better Buildings Network View September 2014 More Documents & Publications Focus Series: OREGON-On Bill Financing Program: On-Bill Financing Brings Lenders and Homeowners On Board Better Buildings Network View | December 2014 On-Bill Financing for Energy E

  15. Better Buildings Network View | November 2015 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    November 2015 Better Buildings Network View | November 2015 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF icon Better Buildings Network View November 2015 More Documents & Publications Lessons Learned: Peer Exchange Calls -- No. 3 Better Buildings Residential Network Membership Form

  16. Multidimensional display controller for displaying to a user an aspect of a multidimensional space visible from a base viewing location along a desired viewing orientation

    DOE Patents [OSTI]

    Davidson, George S.; Anderson, Thomas G.

    2001-01-01

    A display controller allows a user to control a base viewing location, a base viewing orientation, and a relative viewing orientation. The base viewing orientation and relative viewing orientation are combined to determine a desired viewing orientation. An aspect of a multidimensional space visible from the base viewing location along the desired viewing orientation is displayed to the user. The user can change the base viewing location, base viewing orientation, and relative viewing orientation by changing the location or other properties of input objects.

  17. Exaggerated supine oblique view of the cervical spine

    SciTech Connect (OSTI)

    Abel, M.S.

    1982-06-01

    The technique of the 60 degree supine oblique view is described together with anatomic skeletal studies of this projection. The view is convenient for emergency room radiography and useful in other clinical radiography. The view separates widely the anterior and posterior portions of the vertebrae in a side to side projection. This makes for an elongated but detailed view of the articular processes, pedicles, and intervertebral foramina. In the cadavar specimen and clinically the view is shown to be useful in delineating fracture deformities of the articular process and visualizing constriction of the intervertebral foramen superiorly. Encroachment of the foramen superiorly is likely to compromise the emerging nerve root in this area.

  18. Target Fabrication: A View from the Users

    SciTech Connect (OSTI)

    Kyrala, George A.; Balkey, Matthew M.; Barnes, Cris W.; Batha, Steven H.; Christensen, Cindy R.; Cobble, James A.; Fincke, James; Keiter, Paul; Lanier, Nicholas; Paisley, Dennis; Sorem, Michael; Swift, Damian; Workman, Jonathan

    2004-03-15

    Targets are used for a variety of purposes, but ultimately we use them to validate codes that help us predict and understand new phenomena or effects. The sophistication and complexity of High Energy Density Physics (HEDP) and Inertial Confinement Fusion (ICF) targets has increased in to match the advances made in modeling complex phenomena. The targets have changed from simple hohlraums, spherical geometries, and planar foils, to 3-dimensional geometries that require precision in construction, alignment, and metrology. Furthermore, material properties, such as surface morphologies and volume texture, have significant impact on the behavior of the targets and must be measured and controlled. In the following we will discuss how experimental physicists view targets and the influence that target construction has on interpreting the experimental results. We review a representative sampling of targets fabricated at the Los Alamos National Laboratory that are used in different experiments in support of ICF and HEDP.

  19. TARGET FABRICATION: A VIEW FROM THE USERS.

    SciTech Connect (OSTI)

    Kyrala, George A.; Balkey, Matthew M.; Batha, Steven H.; Barnes, Cris W.; Christensen, Cindy; Cobble, James; Fincke, James; Keiter, Paul; Lanier, Nicholas; Paisley, Dennis; Sorem, Michael S.; Swift, Damian; Workman, Jonathan

    2003-07-18

    Targets are used for a variety of purposes, but ultimately we use them to validate codes that help us predict and understand new phenomena or effects. The sophistication and complexity of High Energy Density Physics (HEDP) and Inertial Confinement Fusion (ICF) targets has increased in time to match the advances made in modeling complex phenomena. The targets have changed from simple hohlraums, spherical geometries, and planar foils, to 3-dimensional geometries that require precision in construction, alignment, and metrology. Furthermore, material properties, such as surface morphologies and volume texture, have significant impact on the behavior of the targets and must be measured and controlled. In the following we will discuss how experimental physicists view targets and the influence that target construction has on interpreting the experimental results. We review a representative sampling of targets fabricated at the Los Alamos National Laboratory that are used in different experiments in support of ICF and HEDP.

  20. Improved information analysis - views and actions

    SciTech Connect (OSTI)

    Sheely, K.B.; Manatt, D.R.

    1995-07-01

    The IAEA continues to assess, develop, and test recommendations for strengthening the cost effectiveness of safeguards. The IAEA`s investigation has focused on ways to increase Agency access to data, including access to sites and site data, export/import data, environmental data, open-source data, and other expanded data sources. Although the acquisition of this raw data is essential to strengthening safeguards, the effectiveness of the system is going to be judged by what the Agency does with the data once they have acquired it. Therefore, the IAEA must have the capability to organize, analyze and present the data in a timely manner for internal management evaluation and external dissemination. The United States Department of Energy has established a Safeguards Information Management Systems (SIMS) Initiative to provide support and equipment which will improve the IAEA`s capability to utilize this expanded data to analyze State`s nuclear activities. This paper will present views on steps to improve information analysis and discuss the status of actions undertaken by the SIMS initiative.

  1. September 2015 Most Viewed Documents for Energy Storage, Conversion...

    Office of Scientific and Technical Information (OSTI)

    September 2015 Most Viewed Documents for Energy Storage, Conversion, And Utilization ... of heavy metals: Removal from industrial wastewaters and contaminated soil ...

  2. December 2015 Most Viewed Documents for Energy Storage, Conversion...

    Office of Scientific and Technical Information (OSTI)

    December 2015 Most Viewed Documents for Energy Storage, Conversion, And Utilization ... of heavy metals: Removal from industrial wastewaters and contaminated soil ...

  3. June 2015 Most Viewed Documents for Energy Storage, Conversion...

    Office of Scientific and Technical Information (OSTI)

    June 2015 Most Viewed Documents for Energy Storage, Conversion, And Utilization Process ... of heavy metals: Removal from industrial wastewaters and contaminated soil ...

  4. March 2016 Most Viewed Documents for Energy Storage, Conversion...

    Office of Scientific and Technical Information (OSTI)

    March 2016 Most Viewed Documents for Energy Storage, Conversion, And Utilization Process ... of heavy metals: Removal from industrial wastewaters and contaminated soil ...

  5. BrightView Systems Ltd | Open Energy Information

    Open Energy Info (EERE)

    Ltd Jump to: navigation, search Name: BrightView Systems Ltd Place: Petach-Tikva, Israel Zip: 49510 Product: Has developed an unspecified technology for PV cell manufacture....

  6. Narrow Field of View Zenith Radiometer (NFOV) Handbook (Technical Report) |

    Office of Scientific and Technical Information (OSTI)

    SciTech Connect Technical Report: Narrow Field of View Zenith Radiometer (NFOV) Handbook Citation Details In-Document Search Title: Narrow Field of View Zenith Radiometer (NFOV) Handbook The two-channel narrow field-of-view radiometer (NFOV2) is a ground-based radiometer that looks straight up and measures radiance directly above the instrument at wavelengths of 673 and 870 nm. The field-of-view of the instrument is 1.2 degrees, and the sampling time resolution is one second. Measurements of

  7. July 2013 Most Viewed Documents for Chemistry | OSTI, US Dept...

    Office of Scientific and Technical Information (OSTI)

    July 2013 Most Viewed Documents for Chemistry Science Subject Feed Lithium literature ... Grandy, J. (1997) 35 > Background chemistry for chemical warfare agents and ...

  8. March 2014 Most Viewed Documents for Chemistry | OSTI, US Dept...

    Office of Scientific and Technical Information (OSTI)

    4 Most Viewed Documents for Chemistry Science Subject Feed Flammability characteristics of ... Richards, P. (1989) 19 > Background chemistry for chemical warfare agents and ...

  9. MediaWiki:Pagetitle-view-mainpage | Open Energy Information

    Open Energy Info (EERE)

    Jump to: navigation, search Energy Information and Data | OpenEI.org Retrieved from "http:en.openei.orgwindex.php?titleMediaWiki:Pagetitle-view-mainpage&oldid277068...

  10. January 2013 Most Viewed Documents for Chemistry | OSTI, US Dept...

    Office of Scientific and Technical Information (OSTI)

    January 2013 Most Viewed Documents for Chemistry Dialkylenecarbonate-Bridged Polysilsesquioxanes. Hybrid Organic-Inorganic Sol-Gels with a Thermally Labile Bridging Group Assink, ...

  11. January 2013 Most Viewed Documents for Renewable Energy Sources...

    Office of Scientific and Technical Information (OSTI)

    January 2013 Most Viewed Documents for Renewable Energy Sources Photovoltaic Materials ... UV Test Methods for Encapsulants of Photovoltaic Modules (Presentation) Kempe, M. D. ...

  12. Forest View, Illinois: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    Forest View, Illinois: Energy Resources Jump to: navigation, search Equivalent URI DBpedia Coordinates 41.8086431, -87.7933895 Show Map Loading map... "minzoom":false,"mapping...

  13. A Lidar View of Clouds in Southeastern China

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Lidar View of Clouds in Southeastern China For original submission and image(s), see ARM Research Highlights http:www.arm.govsciencehighlights Research Highlight From May 2008...

  14. June 2015 Most Viewed Documents for Fission And Nuclear Technologies...

    Office of Scientific and Technical Information (OSTI)

    June 2015 Most Viewed Documents for Fission And Nuclear Technologies Estimation of gas ... MIGRATION IN SOILS OF THE CHERNOBYL NUCLEAR POWER PLANT EXCLUSION ZONE Farfan, E ...

  15. December 2015 Most Viewed Documents for Fission And Nuclear Technologi...

    Office of Scientific and Technical Information (OSTI)

    December 2015 Most Viewed Documents for Fission And Nuclear Technologies Estimation of gas ... methods and test results utilized for nuclear core applications (LWBR Development ...

  16. Most Viewed Documents for Fission and Nuclear Technologies: December...

    Office of Scientific and Technical Information (OSTI)

    Most Viewed Documents for Fission and Nuclear Technologies: December 2014 Stress analysis ... States)) (1992) 67 Behavior of spent nuclear fuel in water pool storage Johnson, A.B. ...

  17. The Better Buildings Neighborhood View - September 2012 | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    September 2012 The Better Buildings Neighborhood View - September 2012 Monthly newsletter from the U.S. Department of Energy's Better Buildings Neighborhood Program. PDF icon BB...

  18. Helix Wind Inc formerly ClearView Acquisitions | Open Energy...

    Open Energy Info (EERE)

    (formerly ClearView Acquisitions) Place: San Diego, California Zip: 92113 Sector: Wind energy Product: California-based manufacturer of small scale wind turbines. References: Helix...

  19. September 2013 Most Viewed Documents for Engineering | OSTI,...

    Office of Scientific and Technical Information (OSTI)

    September 2013 Most Viewed Documents for Engineering Science Subject Feed Conduction heat transfer solutions VanSant, J.H. (1980) 190 > Charpy impact test results on five ...

  20. Mountain View Acres, California: Energy Resources | Open Energy...

    Open Energy Info (EERE)

    Mountain View Acres, California: Energy Resources Jump to: navigation, search Equivalent URI DBpedia Coordinates 34.496663, -117.3489352 Show Map Loading map......

  1. Mountain View, California: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    Mountain View, California: Energy Resources Jump to: navigation, search Equivalent URI DBpedia Coordinates 37.3860517, -122.0838511 Show Map Loading map......

  2. Mountain View, Colorado: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    Mountain View, Colorado: Energy Resources Jump to: navigation, search Equivalent URI DBpedia Coordinates 39.7744311, -105.0555389 Show Map Loading map... "minzoom":false,"mapp...

  3. The Better Buildings Neighborhood View -- December 2013 | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    More Documents & Publications The Better Buildings Neighborhood View -- July 2013 Focus Series: Philadelphia Energyworks: In the City of Brotherly Love, Sharing Know-How Leads to ...

  4. September 2015 Most Viewed Documents for Engineering | OSTI,...

    Office of Scientific and Technical Information (OSTI)

    September 2015 Most Viewed Documents for Engineering Heat Treatment Procedure Qualification -- Final Technical Report Robert C. Voigt (2004) 583 Charpy impact test results on five ...

  5. Better Buildings Network View | July-August 2015 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    5 Better Buildings Network View | July-August 2015 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF icon Better Buildings Network View July-August 2015 More Documents & Publications Better Buildings Network View | May 2015 Better Buildings Network View | June 2015 Better Buildings Network View | April

  6. View discovery in OLAP databases through statistical combinatorial optimization

    SciTech Connect (OSTI)

    Hengartner, Nick W; Burke, John; Critchlow, Terence; Joslyn, Cliff; Hogan, Emilie

    2009-01-01

    OnLine Analytical Processing (OLAP) is a relational database technology providing users with rapid access to summary, aggregated views of a single large database, and is widely recognized for knowledge representation and discovery in high-dimensional relational databases. OLAP technologies provide intuitive and graphical access to the massively complex set of possible summary views available in large relational (SQL) structured data repositories. The capability of OLAP database software systems to handle data complexity comes at a high price for analysts, presenting them a combinatorially vast space of views of a relational database. We respond to the need to deploy technologies sufficient to allow users to guide themselves to areas of local structure by casting the space of 'views' of an OLAP database as a combinatorial object of all projections and subsets, and 'view discovery' as an search process over that lattice. We equip the view lattice with statistical information theoretical measures sufficient to support a combinatorial optimization process. We outline 'hop-chaining' as a particular view discovery algorithm over this object, wherein users are guided across a permutation of the dimensions by searching for successive two-dimensional views, pushing seen dimensions into an increasingly large background filter in a 'spiraling' search process. We illustrate this work in the context of data cubes recording summary statistics for radiation portal monitors at US ports.

  7. Compact accelerator for medical therapy

    DOE Patents [OSTI]

    Caporaso, George J.; Chen, Yu-Jiuan; Hawkins, Steven A.; Sampayan, Stephen E.; Paul, Arthur C.

    2010-05-04

    A compact accelerator system having an integrated particle generator-linear accelerator with a compact, small-scale construction capable of producing an energetic (.about.70-250 MeV) proton beam or other nuclei and transporting the beam direction to a medical therapy patient without the need for bending magnets or other hardware often required for remote beam transport. The integrated particle generator-accelerator is actuable as a unitary body on a support structure to enable scanning of a particle beam by direction actuation of the particle generator-accelerator.

  8. Proton beam therapy control system

    DOE Patents [OSTI]

    Baumann, Michael A.; Beloussov, Alexandre V.; Bakir, Julide; Armon, Deganit; Olsen, Howard B.; Salem, Dana

    2010-09-21

    A tiered communications architecture for managing network traffic in a distributed system. Communication between client or control computers and a plurality of hardware devices is administered by agent and monitor devices whose activities are coordinated to reduce the number of open channels or sockets. The communications architecture also improves the transparency and scalability of the distributed system by reducing network mapping dependence. The architecture is desirably implemented in a proton beam therapy system to provide flexible security policies which improve patent safety and facilitate system maintenance and development.

  9. Proton beam therapy control system

    DOE Patents [OSTI]

    Baumann, Michael A.; Beloussov, Alexandre V.; Bakir, Julide; Armon, Deganit; Olsen, Howard B.; Salem, Dana

    2008-07-08

    A tiered communications architecture for managing network traffic in a distributed system. Communication between client or control computers and a plurality of hardware devices is administered by agent and monitor devices whose activities are coordinated to reduce the number of open channels or sockets. The communications architecture also improves the transparency and scalability of the distributed system by reducing network mapping dependence. The architecture is desirably implemented in a proton beam therapy system to provide flexible security policies which improve patent safety and facilitate system maintenance and development.

  10. Proton beam therapy control system

    DOE Patents [OSTI]

    Baumann, Michael A; Beloussov, Alexandre V; Bakir, Julide; Armon, Deganit; Olsen, Howard B; Salem, Dana

    2013-12-03

    A tiered communications architecture for managing network traffic in a distributed system. Communication between client or control computers and a plurality of hardware devices is administered by agent and monitor devices whose activities are coordinated to reduce the number of open channels or sockets. The communications architecture also improves the transparency and scalability of the distributed system by reducing network mapping dependence. The architecture is desirably implemented in a proton beam therapy system to provide flexible security policies which improve patent safety and facilitate system maintenance and development.

  11. Proton beam therapy control system

    DOE Patents [OSTI]

    Baumann, Michael A; Beloussov, Alexandre V; Bakir, Julide; Armon, Deganit; Olsen, Howard B; Salem, Dana

    2013-06-25

    A tiered communications architecture for managing network traffic in a distributed system. Communication between client or control computers and a plurality of hardware devices is administered by agent and monitor devices whose activities are coordinated to reduce the number of open channels or sockets. The communications architecture also improves the transparency and scalability of the distributed system by reducing network mapping dependence. The architecture is desirably implemented in a proton beam therapy system to provide flexible security policies which improve patent safety and facilitate system maintenance and development.

  12. Using ParaView for Scientific Data Visualization | Argonne National

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Laboratory Using ParaView for Scientific Data Visualization May 16, 2016 1:00PM to 2:00PM Presenter Joseph Insley (ALCF) Location Building 401, Room A1100 Type Seminar Series APS Scientific Computation Seminar Series Abstract: ParaView is an open-source, multiplatform data analysis and visualization application. ParaView was developed to analyze extremely large datasets using distributed memory computing resources. It can be run on supercomputers to analyze large datasets as well as on

  13. DOE - NNSA/NFO -- Photo Library News & Views

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    News & Views NNSA/NFO Language Options U.S. DOE/NNSA - Nevada Field Office Photo Library - NTS 50th Anniversary Newsletter (News & Views) This special issue of the NTS News & Views is dedicated to the thousands of men and women at the Nevada National Security Site (NNSS), who for 42 years have provided this Nation with a safe, strong and effective nuclear deterrent. This issue spotlights major events at the NTS from 1951 through 1993. Instructions: Click the photograph THUMBNAIL to

  14. Method for microbeam radiation therapy

    DOE Patents [OSTI]

    Slatkin, Daniel N. (Sound Beach, NY); Dilmanian, F. Avraham (Yaphank, NY); Spanne, Per O. (Shoreham, NY)

    1994-01-01

    A method of performing radiation therapy on a patient, involving exposing a target, usually a tumor, to a therapeutic dose of high energy electromagnetic radiation, preferably X-ray radiation, in the form of at least two non-overlapping microbeams of radiation, each microbeam having a width of less than about 1 millimeter. Target tissue exposed to the microbeams receives a radiation dose during the exposure that exceeds the maximum dose that such tissue can survive. Non-target tissue between the microbeams receives a dose of radiation below the threshold amount of radiation that can be survived by the tissue, and thereby permits the non-target tissue to regenerate. The microbeams may be directed at the target from one direction, or from more than one direction in which case the microbeams overlap within the target tissue enhancing the lethal effect of the irradiation while sparing the surrounding healthy tissue.

  15. Method for microbeam radiation therapy

    DOE Patents [OSTI]

    Slatkin, D.N.; Dilmanian, F.A.; Spanne, P.O.

    1994-08-16

    A method is disclosed of performing radiation therapy on a patient, involving exposing a target, usually a tumor, to a therapeutic dose of high energy electromagnetic radiation, preferably X-ray radiation. The dose is in the form of at least two non-overlapping microbeams of radiation, each microbeam having a width of less than about 1 millimeter. Target tissue exposed to the microbeams receives a radiation dose during the exposure that exceeds the maximum dose that such tissue can survive. Non-target tissue between the microbeams receives a dose of radiation below the threshold amount of radiation that can be survived by the tissue, and thereby permits the non-target tissue to regenerate. The microbeams may be directed at the target from one direction, or from more than one direction in which case the microbeams overlap within the target tissue enhancing the lethal effect of the irradiation while sparing the surrounding healthy tissue. No Drawings

  16. File and Directory Management Tool: view, organize, transfer...

    Office of Scientific and Technical Information (OSTI)

    Title: File and Directory Management Tool: view, organize, transfer files Not Specified Authors: Smith, N. G. ; O'Neill, N. J. ; Spencer, P. N. ; Long, J. W. Publication Date: ...

  17. How can I view submitted materials? | OpenEI Community

    Open Energy Info (EERE)

    Groups Menu You must login in order to post into this group. Recent content Travis Brown and Kamran Baksh, Final Submission For various reasons, you may w... How can I view...

  18. PPPL's "Star Power" video offers compelling view of Laboratory...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    PPPL's "Star Power" video offers compelling view of Laboratory's research By Jeanne Jackson DeVoe September 4, 2013 Tweet Widget Google Plus One Share on Facebook PPPL has released...

  19. January 2013 Most Viewed Documents for Engineering | OSTI, US...

    Office of Scientific and Technical Information (OSTI)

    January 2013 Most Viewed Documents for Engineering Triaxial thermopile array geo-heat-flow sensor Carrigan, C.R.; Hardee, H.C.; Reynolds, G.D.; Steinfort, T.D. Critical experiments ...

  20. April 2013 Most Viewed Documents for Fission And Nuclear Technologies...

    Office of Scientific and Technical Information (OSTI)

    April 2013 Most Viewed Documents for Fission And Nuclear Technologies Science Subject Feed Behavior of spent nuclear fuel in water pool storage Johnson, A.B. Jr. (null) 298 > ...

  1. September 2015 Most Viewed Documents for Fission And Nuclear...

    Office of Scientific and Technical Information (OSTI)

    September 2015 Most Viewed Documents for Fission And Nuclear Technologies Estimation of ... structures Chen, S.S. (1985) 167 LWR nuclear fuel bundle data for use in fuel bundle ...

  2. The Better Buildings Neighborhood View - Summer 2011 | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Summer 2011 The Better Buildings Neighborhood View - Summer 2011 The quarterly update newsletter of the Better Buildings program of the U.S. Department of Energy. PDF icon BB...

  3. West Pleasant View, Colorado: Energy Resources | Open Energy...

    Open Energy Info (EERE)

    Hide Map This article is a stub. You can help OpenEI by expanding it. West Pleasant View is a census-designated place in Jefferson County, Colorado.1 References...

  4. West View, Pennsylvania: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    Hide Map This article is a stub. You can help OpenEI by expanding it. West View is a borough in Allegheny County, Pennsylvania. It falls under Pennsylvania's 4th...

  5. Mountain View Electric Association, Inc- Energy Efficiency Rebates Program

    Broader source: Energy.gov [DOE]

    Mountain View Electric Association, Inc. (MVEA) and Tri-State Generation and Transmission Association Inc., MVEA’s power supplier, offers rebates to MVEA customers who install qualifying energy...

  6. Desert View Highlands, California: Energy Resources | Open Energy...

    Open Energy Info (EERE)

    Hide Map This article is a stub. You can help OpenEI by expanding it. Desert View Highlands is a census-designated place in Los Angeles County, California.1...

  7. March 2015 Most Viewed Documents for Physics | OSTI, US Dept...

    Office of Scientific and Technical Information (OSTI)

    5 Most Viewed Documents for Physics Plastic Gamma Sensors: An Application in Detection of ... (2003) 33 HANDBOOK OF ACCELERATOR PHYSICS AND ENGINEERING; SECTIONS 2.7.1-2.7.5 AND ...

  8. September 2015 Most Viewed Documents for Physics | OSTI, US Dept...

    Office of Scientific and Technical Information (OSTI)

    September 2015 Most Viewed Documents for Physics Plastic Gamma Sensors: An Application in ... J.F. (1983) 38 HANDBOOK OF ACCELERATOR PHYSICS AND ENGINEERING; SECTIONS 2.7.1-2.7.5 AND ...

  9. Most Viewed Documents for Physics: December 2014 | OSTI, US Dept...

    Office of Scientific and Technical Information (OSTI)

    Most Viewed Documents for Physics: December 2014 Cathodic arc plasma deposition Anders, ... L.J. (1990) 17 HANDBOOK OF ACCELERATOR PHYSICS AND ENGINEERING; SECTIONS 2.7.1-2.7.5 AND ...

  10. Chevy Chase View, Maryland: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    is a stub. You can help OpenEI by expanding it. Chevy Chase View is a town in Montgomery County, Maryland. It falls under Maryland's 8th congressional district.12...

  11. September 2013 Most Viewed Documents for Biology And Medicine...

    Office of Scientific and Technical Information (OSTI)

    September 2013 Most Viewed Documents for Biology And Medicine Science Subject Feed Drug ... KRISHNA,C.R. (1999) 27 > Site-Directed Research and Development FY 2012 Annual Report , ...

  12. 'Art of Science' exhibition on view thru November 2012 | Princeton...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    are on view until November 2012 in the Friend Center. Xenon Plasma Accelerator Jerry Ross (fac) PPPL A picture of a Hall-effect thruster (plasma accelerator) plume. The Hall...

  13. Grid Modernization - A View from Abroad | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Grid Modernization - A View from Abroad Grid Modernization - A View from Abroad November 21, 2014 - 4:58pm Addthis Thanks for joining us for #GridWeek! | Graphic by Sarah Gerrity, Energy Department. Thanks for joining us for #GridWeek! | Graphic by Sarah Gerrity, Energy Department. Patricia A. Hoffman Patricia A. Hoffman Assistant Secretary, Office of Electricity Delivery & Energy Reliability While Energy.gov was celebrating #GridWeek this week, I traveled to Japan for the 6th International

  14. Tools for Viewing and Quality Checking ARM Data

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Tools for Viewing and Quality Checking ARM Data S. Bottone and S. Moore Mission Research Corporation Santa Barbara, California Introduction Mission Research Corporation (MRC) is developing software tools to assist the Atmospheric Radiation Measurement (ARM) Data Quality Office with their data inspection tasks. One such tool is NCVweb, a web-based data analysis and visualization tool that allows for easy viewing of ARM NetCDF data files. This tool helps to eliminate the need of and problems

  15. BloombergBusiness: Viewed from space: less corn

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Viewed from space: less corn Viewed from space: less corn U.S. corn production is 2.8 percent smaller than government estimates, according to a daily analysis of infrared satellite images taken of more than 1 million corn fields. September 13, 2015 Domestic corn production will be 13.34 billion bushels, Descartes Labs forecast. Source: Descartes Labs via Bloomberg Domestic corn production will be 13.34 billion bushels, Descartes Labs forecast. Source: Descartes Labs via Bloomberg Corn crop

  16. New ALS Technique Gives Nanoscale Views of Complex Systems

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    New ALS Technique Gives Nanoscale Views of Complex Systems New ALS Technique Gives Nanoscale Views of Complex Systems Print Wednesday, 28 May 2014 00:00 Studying and identifying molecules at the mesoscale has always been challenging-even the best microscopes and spectrometers have difficulty simultaneously identifying and spatially resolving this realm of matter, which ranges from about 10 to 1000 nanometers in size. But ALS researchers recently developed a broadband imaging technique that looks

  17. ALS Technique Gives Novel View of Lithium Battery Dendrite Growth

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ALS Technique Gives Novel View of Lithium Battery Dendrite Growth ALS Technique Gives Novel View of Lithium Battery Dendrite Growth Print Thursday, 24 April 2014 09:46 Lithium-ion batteries, popular in today's electronic devices and electric vehicles, could gain significant energy density if their graphite anodes were replaced with lithium metal anodes. But there's a major concern with substituting lithium-when the battery cycles, microscopic fibers of the lithium anodes ("dendrites")

  18. Modern Radiation Therapy for Primary Cutaneous Lymphomas: Field and Dose Guidelines From the International Lymphoma Radiation Oncology Group

    SciTech Connect (OSTI)

    Specht, Lena; Dabaja, Bouthaina; Illidge, Tim; Wilson, Lynn D.; Hoppe, Richard T.

    2015-05-01

    Primary cutaneous lymphomas are a heterogeneous group of diseases. They often remain localized, and they generally have a more indolent course and a better prognosis than lymphomas in other locations. They are highly radiosensitive, and radiation therapy is an important part of the treatment, either as the sole treatment or as part of a multimodality approach. Radiation therapy of primary cutaneous lymphomas requires the use of special techniques that form the focus of these guidelines. The International Lymphoma Radiation Oncology Group has developed these guidelines after multinational meetings and analysis of available evidence. The guidelines represent an agreed consensus view of the International Lymphoma Radiation Oncology Group steering committee on the use of radiation therapy in primary cutaneous lymphomas in the modern era.

  19. Better Buildings Network View | July-August 2014 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    4 Better Buildings Network View | July-August 2014 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's Better Buildings Residential Network. PDF icon Better Buildings Network View July-August 2014 More Documents & Publications Opportunities through the PowerSaver Loan Program Better Buildings Network View | September 2014 Better Buildings Network View | March

  20. Shape memory polymer foams for endovascular therapies (Patent...

    Office of Scientific and Technical Information (OSTI)

    polymer foams for endovascular therapies Title: Shape memory polymer foams for endovascular therapies A system for occluding a physical anomaly. One embodiment comprises a shape ...

  1. BERAC Subcommittee Report on Boron Neutron Capture Therapy (BNCT...

    Office of Science (SC) Website

    BERAC Subcommittee Report on Boron Neutron Capture Therapy (BNCT) Clinical Trials. ... ChargesReports BERAC Subcommittee Report on Boron Neutron Capture Therapy (BNCT) Clinical ...

  2. DOE Research Contributions to Radiation and Cancer Therapy

    Office of Scientific and Technical Information (OSTI)

    DOE Research Contributions to Radiation and Cancer Therapy Resources with Additional ... made many contributions to radiation and cancer therapy, including PEREGRINE and Boron ...

  3. Shape memory polymer foams for endovascular therapies (Patent...

    Office of Scientific and Technical Information (OSTI)

    Patent: Shape memory polymer foams for endovascular therapies Citation Details In-Document Search Title: Shape memory polymer foams for endovascular therapies A system for ...

  4. Rational design and adaptive management of combination therapies...

    Office of Scientific and Technical Information (OSTI)

    therapies for Hepatitis C virus infection Prev Next Title: Rational design and adaptive management of combination therapies for Hepatitis C virus infection Recent ...

  5. Rational Design and Adaptive Management of Combination Therapies...

    Office of Scientific and Technical Information (OSTI)

    of Combination Therapies for Hepatitis C Virus Infection CrossMark click for updates n ... Design and Adaptive Management of Combination Therapies for Hepatitis C Virus Infection. ...

  6. Shape memory polymer foams for endovascular therapies (Patent...

    Office of Scientific and Technical Information (OSTI)

    Shape memory polymer foams for endovascular therapies Title: Shape memory polymer foams for endovascular therapies A system for occluding a physical anomaly. One embodiment ...

  7. DOE Tour of Zero Floorplans: Marine Drive by Clifton View Homes |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Marine Drive by Clifton View Homes DOE Tour of Zero Floorplans: Marine Drive by Clifton View Homes DOE Tour of Zero Floorplans: Marine Drive by Clifton View

  8. DOE Tour of Zero Floorplans: Port Hadlock by Clifton View Homes |

    Energy Savers [EERE]

    Department of Energy Port Hadlock by Clifton View Homes DOE Tour of Zero Floorplans: Port Hadlock by Clifton View Homes DOE Tour of Zero Floorplans: Port Hadlock by Clifton View Homes

  9. Differing professional views or opinions: 1994 Special Review Panel

    SciTech Connect (OSTI)

    1996-09-01

    In July 1994, the Executive Director for Operations of the US Nuclear Regulatory Commission (NRC) appointed a Special Review Panel to assess the Differing Professional View or Opinion (DPV/DPO) process, including its effectiveness, how well it is understood by employees, and the organizational climate for having such views aired and properly decided. An additional area within this review was to address the effectiveness of the DPO procedures as they pertain to public access and confidentiality. Further, the Panel was charged with the review of the submittals completed since the last review to identify employees who made significant contributions to the agency or to the public health and safety but had not been adequately recognized for this contribution. The report presents the Special Review Panel`s evaluation of the NRC`s current process for dealing with Differing Professional Views or Opinions. Provided in this report are the results of an employee opinion survey on the process; highlights and suggestions from interviews with individuals who had submitted a Differing Professional View or Opinion, as well as with agency managers directly involved with the Differing Professional Views or Opinions process; and the Special Review Panel`s recommendations for improving the DPV/DPO process.

  10. V-195: RSA Authentication Manager Lets Local Users View the Administra...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    5: RSA Authentication Manager Lets Local Users View the Administrative Account Password V-195: RSA Authentication Manager Lets Local Users View the Administrative Account Password...

  11. Nonclinical safety strategies for stem cell therapies

    SciTech Connect (OSTI)

    Sharpe, Michaela E.; Morton, Daniel; Rossi, Annamaria

    2012-08-01

    Recent breakthroughs in stem cell biology, especially the development of the induced pluripotent stem cell techniques, have generated tremendous enthusiasm and efforts to explore the therapeutic potential of stem cells in regenerative medicine. Stem cell therapies are being considered for the treatment of degenerative diseases, inflammatory conditions, cancer and repair of damaged tissue. The safety of a stem cell therapy depends on many factors including the type of cell therapy, the differentiation status and proliferation capacity of the cells, the route of administration, the intended clinical location, long term survival of the product and/or engraftment, the need for repeated administration, the disease to be treated and the age of the population. Understanding the product profile of the intended therapy is crucial to the development of the nonclinical safety study design.

  12. Novel targeted therapy for stomach cancer

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Novel targeted therapy for stomach cancer Novel targeted therapy for stomach cancer This finding has the potential to save thousand of lives a year by delivering a more effective, targeted treatment for cancer patients. November 1, 2015 New research at Los Alamos National Laboratory and the Wellcome Trust Sanger Institute shows a molecular fingerprint in stomach cancer that shows it can be treated with platinum drugs and/or molecular inhibitors known as PARP (poly ADP ribose polymerase). New

  13. File and Directory Management Tool: view, organize, transfer files () |

    Office of Scientific and Technical Information (OSTI)

    SciTech Connect File and Directory Management Tool: view, organize, transfer files Citation Details Software Request Title: File and Directory Management Tool: view, organize, transfer files Not Specified Authors: Smith, N. G. ; O'Neill, N. J. ; Spencer, P. N. ; Long, J. W. Publication Date: 2008-03-14 OSTI Identifier: 1231070 Report Number(s): Hopper V2.0; 002218MLTPL00 LLNL-CODE-403380 DOE Contract Number: AC52-07NA27344 Software Revision: 00 Software Package Number: 002218 Software

  14. Fermilab | Tritium at Fermilab | Indian Creek Aerial View

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Indian Creek Aerial View Indian Creek Aerial View Indian Creek is a small creek that originates on the Fermilab site and leaves the lab at its southwest corner. The flow of water in the creek varies with the amount of rain that falls during the year. At present, Indian Creek has very low levels of water. Even at its strongest flow, Indian Creek is a shallow creek with a width of a few feet where it leaves the Fermilab site. Just outside the Fermilab site, the creek flows through ponds in the

  15. Partial growth plate closure: apex view on bone scan

    SciTech Connect (OSTI)

    Howman-Giles, R.; Trochei, M.; Yeates, K.; Middleton, R.; Barrett, I.; Scougall, J.; Whiteway, D.

    1985-01-01

    A new technique of using /sup 99m/Tc bone scan to assess partial closure of the growth plate is described. The site and degree of osseous fusion can be obtained by using the apex view. The technique has the potential of assessing serially the growth of a plate before and after surgery.

  16. A Treatment Planning Method for Sequentially Combining Radiopharmaceutical Therapy and External Radiation Therapy;External beam therapy; Radiopharmaceutical therapy; Three-dimensional dosimetry; Treatment planning

    SciTech Connect (OSTI)

    Hobbs, Robert F.; McNutt, Todd; Baechler, Sebastien; He Bin; Esaias, Caroline E.; Frey, Eric C.; Loeb, David M.; Wahl, Richard L.; Shokek, Ori; Sgouros, George

    2011-07-15

    Purpose: Effective cancer treatment generally requires combination therapy. The combination of external beam therapy (XRT) with radiopharmaceutical therapy (RPT) requires accurate three-dimensional dose calculations to avoid toxicity and evaluate efficacy. We have developed and tested a treatment planning method, using the patient-specific three-dimensional dosimetry package 3D-RD, for sequentially combined RPT/XRT therapy designed to limit toxicity to organs at risk. Methods and Materials: The biologic effective dose (BED) was used to translate voxelized RPT absorbed dose (D{sub RPT}) values into a normalized total dose (or equivalent 2-Gy-fraction XRT absorbed dose), NTD{sub RPT} map. The BED was calculated numerically using an algorithmic approach, which enabled a more accurate calculation of BED and NTD{sub RPT}. A treatment plan from the combined Samarium-153 and external beam was designed that would deliver a tumoricidal dose while delivering no more than 50 Gy of NTD{sub sum} to the spinal cord of a patient with a paraspinal tumor. Results: The average voxel NTD{sub RPT} to tumor from RPT was 22.6 Gy (range, 1-85 Gy); the maximum spinal cord voxel NTD{sub RPT} from RPT was 6.8 Gy. The combined therapy NTD{sub sum} to tumor was 71.5 Gy (range, 40-135 Gy) for a maximum voxel spinal cord NTD{sub sum} equal to the maximum tolerated dose of 50 Gy. Conclusions: A method that enables real-time treatment planning of combined RPT-XRT has been developed. By implementing a more generalized conversion between the dose values from the two modalities and an activity-based treatment of partial volume effects, the reliability of combination therapy treatment planning has been expanded.

  17. Narrow Field of View Zenith Radiometer (NFOV) Handbook

    SciTech Connect (OSTI)

    Chiu, C; Marshak, A; Hodges, G; Barnard, JC; Schmelzer, J

    2008-11-01

    The two-channel narrow field-of-view radiometer (NFOV2) is a ground-based radiometer that looks straight up and measures radiance directly above the instrument at wavelengths of 673 and 870 nm. The field-of-view of the instrument is 1.2 degrees, and the sampling time resolution is one second. Measurements of the NFOV2 have been used to retrieve optical properties for overhead clouds that range from patchy to overcast. With a one-second sampling rate of the NFOV2, faster than almost any other ARM Climate Research Facility (ACRF) instrument, we are able, for the first time, to capture changes in cloud optical properties at the natural time scale of cloud evolution.

  18. March 2016 Most Viewed Documents for Energy Storage, Conversion, And

    Office of Scientific and Technical Information (OSTI)

    Utilization | OSTI, US Dept of Energy, Office of Scientific and Technical Information March 2016 Most Viewed Documents for Energy Storage, Conversion, And Utilization Process Equipment Cost Estimation, Final Report H.P. Loh; Jennifer Lyons; Charles W. White, III (2002) 2444 Automotive vehicle sensors Sheen, S.H.; Raptis, A.C.; Moscynski, M.J. (1995) 726 Separation of heavy metals: Removal from industrial wastewaters and contaminated soil Peters, R.W.; Shem, L. (1993) 701 Continuously

  19. New ALS Technique Gives Nanoscale Views of Complex Systems

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    New ALS Technique Gives Nanoscale Views of Complex Systems Print Studying and identifying molecules at the mesoscale has always been challenging-even the best microscopes and spectrometers have difficulty simultaneously identifying and spatially resolving this realm of matter, which ranges from about 10 to 1000 nanometers in size. But ALS researchers recently developed a broadband imaging technique that looks inside the mesoscale realm with unprecedented sensitivity and range. The new technique,

  20. New ALS Technique Gives Nanoscale Views of Complex Systems

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    New ALS Technique Gives Nanoscale Views of Complex Systems Print Studying and identifying molecules at the mesoscale has always been challenging-even the best microscopes and spectrometers have difficulty simultaneously identifying and spatially resolving this realm of matter, which ranges from about 10 to 1000 nanometers in size. But ALS researchers recently developed a broadband imaging technique that looks inside the mesoscale realm with unprecedented sensitivity and range. The new technique,

  1. New ALS Technique Gives Nanoscale Views of Complex Systems

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    New ALS Technique Gives Nanoscale Views of Complex Systems Print Studying and identifying molecules at the mesoscale has always been challenging-even the best microscopes and spectrometers have difficulty simultaneously identifying and spatially resolving this realm of matter, which ranges from about 10 to 1000 nanometers in size. But ALS researchers recently developed a broadband imaging technique that looks inside the mesoscale realm with unprecedented sensitivity and range. The new technique,

  2. New ALS Technique Gives Nanoscale Views of Complex Systems

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    New ALS Technique Gives Nanoscale Views of Complex Systems Print Studying and identifying molecules at the mesoscale has always been challenging-even the best microscopes and spectrometers have difficulty simultaneously identifying and spatially resolving this realm of matter, which ranges from about 10 to 1000 nanometers in size. But ALS researchers recently developed a broadband imaging technique that looks inside the mesoscale realm with unprecedented sensitivity and range. The new technique,

  3. New ALS Technique Gives Nanoscale Views of Complex Systems

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ALS Technique Gives Nanoscale Views of Complex Systems Print Studying and identifying molecules at the mesoscale has always been challenging-even the best microscopes and spectrometers have difficulty simultaneously identifying and spatially resolving this realm of matter, which ranges from about 10 to 1000 nanometers in size. But ALS researchers recently developed a broadband imaging technique that looks inside the mesoscale realm with unprecedented sensitivity and range. The new technique,

  4. New ALS Technique Gives Nanoscale Views of Complex Systems

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    New ALS Technique Gives Nanoscale Views of Complex Systems Print Studying and identifying molecules at the mesoscale has always been challenging-even the best microscopes and spectrometers have difficulty simultaneously identifying and spatially resolving this realm of matter, which ranges from about 10 to 1000 nanometers in size. But ALS researchers recently developed a broadband imaging technique that looks inside the mesoscale realm with unprecedented sensitivity and range. The new technique,

  5. ALS Technique Gives Novel View of Lithium Battery Dendrite Growth

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ALS Technique Gives Novel View of Lithium Battery Dendrite Growth Print Lithium-ion batteries, popular in today's electronic devices and electric vehicles, could gain significant energy density if their graphite anodes were replaced with lithium metal anodes. But there's a major concern with substituting lithium-when the battery cycles, microscopic fibers of the lithium anodes ("dendrites") form on the surface of the lithium electrode and spread across the electrolyte until they reach

  6. September 2013 Most Viewed Documents for Energy Storage, Conversion, And

    Office of Scientific and Technical Information (OSTI)

    Utilization | OSTI, US Dept of Energy, Office of Scientific and Technical Information September 2013 Most Viewed Documents for Energy Storage, Conversion, And Utilization Process Equipment Cost Estimation, Final Report H.P. Loh; Jennifer Lyons; Charles W. White, III (2002) 169 Evaluation of the 2010 Toyota Prius Hybrid Synergy Drive System Burress, Timothy A [ORNL]; Campbell, Steven L [ORNL]; Coomer, Chester [ORNL]; Ayers, Curtis William [ORNL]; Wereszczak, Andrew A [ORNL]; Cunningham,

  7. September 2013 Most Viewed Documents for Fission And Nuclear Technologies |

    Office of Scientific and Technical Information (OSTI)

    OSTI, US Dept of Energy, Office of Scientific and Technical Information September 2013 Most Viewed Documents for Fission And Nuclear Technologies Science Subject Feed Estimation of gas leak rates through very small orifices and channels. [From sealed PuO/sub 2/ containers under accident conditions] Bomelburg, H.J. (1977) 133 /> Stress analysis and evaluation of a rectangular pressure vessel. [For equipment for sampling Hanford tank radwaste] Rezvani, M.A.; Ziada, H.H. (Westinghouse

  8. September 2013 Most Viewed Documents for Mathematics And Computing | OSTI,

    Office of Scientific and Technical Information (OSTI)

    US Dept of Energy, Office of Scientific and Technical Information September 2013 Most Viewed Documents for Mathematics And Computing Science Subject Feed Process Equipment Cost Estimation, Final Report H.P. Loh; Jennifer Lyons; Charles W. White, III (2002) 169 /> Lecture notes for introduction to safety and health Biele, F. (1992) 57 /> A comparison of risk assessment techniques from qualitative to quantitative Altenbach, T.J. (1995) 50 /> Computational procedures for determining

  9. September 2013 Most Viewed Documents for Renewable Energy Sources | OSTI,

    Office of Scientific and Technical Information (OSTI)

    US Dept of Energy, Office of Scientific and Technical Information September 2013 Most Viewed Documents for Renewable Energy Sources Science Subject Feed Chapter 11. Heat Exchangers Rafferty, Kevin D.; Culver, Gene (1998) 362 /> Wet cooling towers: rule-of-thumb design and simulation Leeper, S.A. (1981) 103 /> Chapter 17. Engineering cost analysis Higbee, Charles V. (1998) 79 /> Advanced Electric Submersible Pump Design Tool for Geothermal Applications Xuele Qi; Norman Turnquist;

  10. September 2015 Most Viewed Documents for Energy Storage, Conversion, And

    Office of Scientific and Technical Information (OSTI)

    Utilization | OSTI, US Dept of Energy, Office of Scientific and Technical Information September 2015 Most Viewed Documents for Energy Storage, Conversion, And Utilization Process Equipment Cost Estimation, Final Report H.P. Loh; Jennifer Lyons; Charles W. White, III (2002) 1049 Separation of heavy metals: Removal from industrial wastewaters and contaminated soil Peters, R.W.; Shem, L. (1993) 285 An Improved Method of Manufacturing Corrugated Boxes: Lateral Corrugator Frank C. Murray Ph.D.; ,

  11. September 2015 Most Viewed Documents for Environmental Sciences | OSTI, US

    Office of Scientific and Technical Information (OSTI)

    Dept of Energy, Office of Scientific and Technical Information September 2015 Most Viewed Documents for Environmental Sciences Separation of heavy metals: Removal from industrial wastewaters and contaminated soil Peters, R.W.; Shem, L. (1993) 285 Statistical methods for environmental pollution monitoring Gilbert, R.O. (1987) 126 Building a secondary containment system Broder, M.F. (1994) 121 Study of using oxygen-enriched combustion air for locomotive diesel engines Poola, R.B.; Sekar, R.

  12. September 2015 Most Viewed Documents for Fission And Nuclear Technologies |

    Office of Scientific and Technical Information (OSTI)

    OSTI, US Dept of Energy, Office of Scientific and Technical Information September 2015 Most Viewed Documents for Fission And Nuclear Technologies Estimation of gas leak rates through very small orifices and channels. [From sealed PuO/sub 2/ containers under accident conditions] Bomelburg, H.J. (1977) 444 System Definition and Analysis: Power Plant Design and Layout NONE (1996) 273 Stress analysis and evaluation of a rectangular pressure vessel. [For equipment for sampling Hanford tank

  13. September 2015 Most Viewed Documents for Mathematics And Computing | OSTI,

    Office of Scientific and Technical Information (OSTI)

    US Dept of Energy, Office of Scientific and Technical Information September 2015 Most Viewed Documents for Mathematics And Computing Process Equipment Cost Estimation, Final Report H.P. Loh; Jennifer Lyons; Charles W. White, III (2002) 1049 Lecture notes for introduction to safety and health Biele, F. (1992) 333 A comparison of risk assessment techniques from qualitative to quantitative Altenbach, T.J. (1995) 286 Ferrite Measurement in Austenitic and Duplex Stainless Steel Castings -

  14. September 2015 Most Viewed Documents for Renewable Energy Sources | OSTI,

    Office of Scientific and Technical Information (OSTI)

    US Dept of Energy, Office of Scientific and Technical Information September 2015 Most Viewed Documents for Renewable Energy Sources Calculation of brine properties. [Above 80/sup 0/F and for salt content between 5 and 25%] Dittman, G.L. (1977) 257 Aerodynamic characteristics of seven symmetrical airfoil sections through 180-degree angle of attack for use in aerodynamic analysis of vertical axis wind turbines Sheldahl, R E; Klimas, P C (1981) 217 Thermal conductivity of aqueous NaCl solutions

  15. January 2013 Most Viewed Documents for Energy Storage, Conversion, And

    Office of Scientific and Technical Information (OSTI)

    Utilization | OSTI, US Dept of Energy, Office of Scientific and Technical Information January 2013 Most Viewed Documents for Energy Storage, Conversion, And Utilization Energy Technology Perspectives 2012: Executive Summary [Portuguese version] NONE Energy indicators for electricity production : comparing technologies and the nature of the indicators Energy Payback Ratio (EPR), Net Energy Ratio (NER) and Cumulative Energy Demand (CED). [Oestfoldforskning AS] Raadal, Hanne Lerche [Ostfold

  16. January 2013 Most Viewed Documents for Environmental Sciences | OSTI, US

    Office of Scientific and Technical Information (OSTI)

    Dept of Energy, Office of Scientific and Technical Information January 2013 Most Viewed Documents for Environmental Sciences Horizontal Advanced Tensiometer Hubbell, Joel M.; Sisson, James B. 2 micron LIDAR for laser-based remote sensing: Flight demonstration and application survey Wagener, T.J.; Demma, N.; Kmetec, J.D.; Kubo, T.S. [Honeywell Technology Cent, Bloomington, MN (United States)] Streamflow and selected precipitation data for Yucca Mountain and vicinity, Nye County, Nevada, water

  17. January 2013 Most Viewed Documents for Power Generation And Distribution |

    Office of Scientific and Technical Information (OSTI)

    OSTI, US Dept of Energy, Office of Scientific and Technical Information January 2013 Most Viewed Documents for Power Generation And Distribution Lessons from Large-Scale Renewable Energy Integration Studies: Preprint Bird, L.; Milligan, M. Small punch creep test: A promising methodology for high temperature plant components life evaluation Tettamanti, S. [CISE SpA, Milan (Italy)]; Crudeli, R. [ENEL SpA, Milan (Italy)] Failure analyses and weld repair of boiler feed water pumps Vulpen, R. van

  18. June 2014 Most Viewed Documents for Energy Storage, Conversion, And

    Office of Scientific and Technical Information (OSTI)

    Utilization | OSTI, US Dept of Energy, Office of Scientific and Technical Information June 2014 Most Viewed Documents for Energy Storage, Conversion, And Utilization Science Subject Feed Process Equipment Cost Estimation, Final Report H.P. Loh; Jennifer Lyons; Charles W. White, III (2002) 337 /> Seventh Edition Fuel Cell Handbook NETL (2004) 118 /> Energy Saving Potentials and Air Quality Benefits of Urban HeatIslandMitigation Akbari, Hashem (2005) 76 /> Evaluation of 2004 Toyota

  19. June 2015 Most Viewed Documents for Energy Storage, Conversion, And

    Office of Scientific and Technical Information (OSTI)

    Utilization | OSTI, US Dept of Energy, Office of Scientific and Technical Information June 2015 Most Viewed Documents for Energy Storage, Conversion, And Utilization Process Equipment Cost Estimation, Final Report H.P. Loh; Jennifer Lyons; Charles W. White, III (2002) 833 Separation of heavy metals: Removal from industrial wastewaters and contaminated soil Peters, R.W.; Shem, L. (1993) 234 An Improved Method of Manufacturing Corrugated Boxes: Lateral Corrugator Frank C. Murray Ph.D.; , Roman

  20. June 2015 Most Viewed Documents for Fission And Nuclear Technologies |

    Office of Scientific and Technical Information (OSTI)

    OSTI, US Dept of Energy, Office of Scientific and Technical Information June 2015 Most Viewed Documents for Fission And Nuclear Technologies Estimation of gas leak rates through very small orifices and channels. [From sealed PuO/sub 2/ containers under accident conditions] Bomelburg, H.J. (1977) 305 System Definition and Analysis: Power Plant Design and Layout NONE (1996) 296 Stress analysis and evaluation of a rectangular pressure vessel. [For equipment for sampling Hanford tank radwaste]

  1. March 2014 Most Viewed Documents for Energy Storage, Conversion, And

    Office of Scientific and Technical Information (OSTI)

    Utilization | OSTI, US Dept of Energy, Office of Scientific and Technical Information 4 Most Viewed Documents for Energy Storage, Conversion, And Utilization Science Subject Feed Process Equipment Cost Estimation, Final Report H.P. Loh; Jennifer Lyons; Charles W. White, III (2002) 291 /> Energy Saving Potentials and Air Quality Benefits of Urban HeatIslandMitigation Akbari, Hashem (2005) 85 /> Seventh Edition Fuel Cell Handbook NETL (2004) 68 /> Separation of heavy metals: Removal

  2. March 2015 Most Viewed Documents for Energy Storage, Conversion, And

    Office of Scientific and Technical Information (OSTI)

    Utilization | OSTI, US Dept of Energy, Office of Scientific and Technical Information 5 Most Viewed Documents for Energy Storage, Conversion, And Utilization Process Equipment Cost Estimation, Final Report H.P. Loh; Jennifer Lyons; Charles W. White, III (2002) 1019 Separation of heavy metals: Removal from industrial wastewaters and contaminated soil Peters, R.W.; Shem, L. (1993) 229 Energy Saving Potentials and Air Quality Benefits of Urban HeatIslandMitigation Akbari, Hashem (2005) 218 An

  3. March 2015 Most Viewed Documents for Fission And Nuclear Technologies |

    Office of Scientific and Technical Information (OSTI)

    OSTI, US Dept of Energy, Office of Scientific and Technical Information 5 Most Viewed Documents for Fission And Nuclear Technologies Stress analysis and evaluation of a rectangular pressure vessel. [For equipment for sampling Hanford tank radwaste] Rezvani, M.A.; Ziada, H.H. (Westinghouse Hanford Co., Richland, WA (United States)); Shurrab, M.S. (Westinghouse Savannah River Co., Aiken, SC (United States)) (1992) 223 Estimation of gas leak rates through very small orifices and channels. [From

  4. Most Viewed Documents for Energy Storage, Conversion, and Utilization:

    Office of Scientific and Technical Information (OSTI)

    December 2014 | OSTI, US Dept of Energy, Office of Scientific and Technical Information Most Viewed Documents for Energy Storage, Conversion, and Utilization: December 2014 Process Equipment Cost Estimation, Final Report H.P. Loh; Jennifer Lyons; Charles W. White, III (2002) 322 Energy Saving Potentials and Air Quality Benefits of Urban HeatIslandMitigation Akbari, Hashem (2005) 107 Separation of heavy metals: Removal from industrial wastewaters and contaminated soil Peters, R.W.; Shem, L.

  5. Most Viewed Documents for Environmental Sciences: December 2014 | OSTI, US

    Office of Scientific and Technical Information (OSTI)

    Dept of Energy, Office of Scientific and Technical Information Most Viewed Documents for Environmental Sciences: December 2014 Separation of heavy metals: Removal from industrial wastewaters and contaminated soil Peters, R.W.; Shem, L. (1993) 107 Improved Magnus` form approximation of saturation vapor pressure Alduchov, O.A.; Eskridge, R.E. [National Oceanic and Atmospheric Administration, Asheville, NC (United States). National Climatic Data Center] (1997) 50 Statistical methods for

  6. Most Viewed Documents for Fission and Nuclear Technologies: December 2014 |

    Office of Scientific and Technical Information (OSTI)

    OSTI, US Dept of Energy, Office of Scientific and Technical Information Most Viewed Documents for Fission and Nuclear Technologies: December 2014 Stress analysis and evaluation of a rectangular pressure vessel. [For equipment for sampling Hanford tank radwaste] Rezvani, M.A.; Ziada, H.H. (Westinghouse Hanford Co., Richland, WA (United States)); Shurrab, M.S. (Westinghouse Savannah River Co., Aiken, SC (United States)) (1992) 67 Behavior of spent nuclear fuel in water pool storage Johnson,

  7. Most Viewed Documents for Mathematics and Computing: December 2014 | OSTI,

    Office of Scientific and Technical Information (OSTI)

    US Dept of Energy, Office of Scientific and Technical Information Most Viewed Documents for Mathematics and Computing: December 2014 Process Equipment Cost Estimation, Final Report H.P. Loh; Jennifer Lyons; Charles W. White, III (2002) 322 Levenberg--Marquardt algorithm: implementation and theory More, J.J. (1977) 64 A comparison of risk assessment techniques from qualitative to quantitative Altenbach, T.J. (1995) 51 Lecture notes for introduction to safety and health Biele, F. (1992) 50

  8. Most Viewed Documents for Renewable Energy Sources: December 2014 | OSTI,

    Office of Scientific and Technical Information (OSTI)

    US Dept of Energy, Office of Scientific and Technical Information Most Viewed Documents for Renewable Energy Sources: December 2014 Chapter 11. Heat Exchangers Rafferty, Kevin D.; Culver, Gene (1998) 339 Generalized displacement correlation method for estimating stress intensity factors Fu, P; Johnson, S M; Settgast, R R; Carrigan, C R (2011) 107 Seventh Edition Fuel Cell Handbook NETL (2004) 96 Advanced Electric Submersible Pump Design Tool for Geothermal Applications Xuele Qi; Norman

  9. December 2015 Most Viewed Documents for Energy Storage, Conversion, And

    Office of Scientific and Technical Information (OSTI)

    Utilization | OSTI, US Dept of Energy, Office of Scientific and Technical Information December 2015 Most Viewed Documents for Energy Storage, Conversion, And Utilization Process Equipment Cost Estimation, Final Report H.P. Loh; Jennifer Lyons; Charles W. White, III (2002) 1446 Separation of heavy metals: Removal from industrial wastewaters and contaminated soil Peters, R.W.; Shem, L. (1993) 452 Automotive vehicle sensors Sheen, S.H.; Raptis, A.C.; Moscynski, M.J. (1995) 373 An Improved

  10. December 2015 Most Viewed Documents for Environmental Sciences | OSTI, US

    Office of Scientific and Technical Information (OSTI)

    Dept of Energy, Office of Scientific and Technical Information December 2015 Most Viewed Documents for Environmental Sciences Separation of heavy metals: Removal from industrial wastewaters and contaminated soil Peters, R.W.; Shem, L. (1993) 452 Building a secondary containment system Broder, M.F. (1994) 171 Statistical methods for environmental pollution monitoring Gilbert, R.O. (1987) 116 Ammonia usage in vapor compression for refrigeration and air-conditioning in the United States

  11. December 2015 Most Viewed Documents for Fission And Nuclear Technologies |

    Office of Scientific and Technical Information (OSTI)

    OSTI, US Dept of Energy, Office of Scientific and Technical Information December 2015 Most Viewed Documents for Fission And Nuclear Technologies Estimation of gas leak rates through very small orifices and channels. [From sealed PuO/sub 2/ containers under accident conditions] Bomelburg, H.J. (1977) 432 System Definition and Analysis: Power Plant Design and Layout NONE (1996) 323 Stress analysis and evaluation of a rectangular pressure vessel. [For equipment for sampling Hanford tank

  12. Porphyrins for boron neutron capture therapy

    DOE Patents [OSTI]

    Miura, Michiko; Gabel, Detlef

    1990-01-01

    Novel compounds for treatment of brain tumors in Boron Neutron Capture Therapy are disclosed. A method for preparing the compounds as well as pharmaceutical compositions containing said compounds are also disclosed. The compounds are water soluble, non-toxic and non-labile boronated porphyrins which show significant uptake and retention in tumors.

  13. Brachial Plexus-Associated Neuropathy After High-Dose Radiation Therapy for Head-and-Neck Cancer

    SciTech Connect (OSTI)

    Chen, Allen M.; Hall, William H.; Li, Judy; Beckett, Laurel; Farwell, D. Gregory; Lau, Derick H.; Purdy, James A.

    2012-09-01

    Purpose: To identify clinical and treatment-related predictors of brachial plexus-associated neuropathies after radiation therapy for head-and-neck cancer. Methods and Materials: Three hundred thirty patients who had previously completed radiation therapy for head-and-neck cancer were prospectively screened using a standardized instrument for symptoms of neuropathy thought to be related to brachial plexus injury. All patients were disease-free at the time of screening. The median time from completion of radiation therapy was 56 months (range, 6-135 months). One-hundred fifty-five patients (47%) were treated by definitive radiation therapy, and 175 (53%) were treated postoperatively. Radiation doses ranged from 50 to 74 Gy (median, 66 Gy). Intensity-modulated radiation therapy was used in 62% of cases, and 133 patients (40%) received concurrent chemotherapy. Results: Forty patients (12%) reported neuropathic symptoms, with the most common being ipsilateral pain (50%), numbness/tingling (40%), motor weakness, and/or muscle atrophy (25%). When patients with <5 years of follow-up were excluded, the rate of positive symptoms increased to 22%. On univariate analysis, the following factors were significantly associated with brachial plexus symptoms: prior neck dissection (p = 0.01), concurrent chemotherapy (p = 0.01), and radiation maximum dose (p < 0.001). Cox regression analysis confirmed that both neck dissection (p < 0.001) and radiation maximum dose (p < 0.001) were independently predictive of symptoms. Conclusion: The incidence of brachial plexus-associated neuropathies after radiation therapy for head-and-neck cancer may be underreported. In view of the dose-response relationship identified, limiting radiation dose to the brachial plexus should be considered when possible.

  14. Proton Therapy for Cancer: Current Status, Promise and Challenges...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    March 9, 2016, 4:15pm to 5:30pm Colloquia MBG Auditorium Proton Therapy for Cancer: Current Status, Promise and Challenges Dr. Dennis Mah ProCure Proton Therapy Center Colloquium...

  15. Microsoft PowerPoint - MBPCC CAMD Cancer Therapy Program, 12...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Bird Perkins Cancer Center's CAMD Cancer Therapy Research Program CAMD Cancer Therapy Research Program Kenneth R Hogstrom, PhD, PI Chief of Physics Mary Bird Perkins Cancer Center...

  16. COLLOQUIUM: Proton Therapy for Cancer: Current Status, Promise and

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Challenges | Princeton Plasma Physics Lab 25, 2016, 4:15pm to 5:30pm Colloquia MBG Auditorium, PPPL (284 cap.) COLLOQUIUM: Proton Therapy for Cancer: Current Status, Promise and Challenges Dr. Dennis Mah ProCure Proton Therapy Center This presentation will provide a physicist's perspective on a proton therapy for cancer treatment. It will include a context of how radiation therapy fits into cancer management overall with an emphasis on the differences between proton and conventional

  17. April 2013 Most Viewed Documents for Energy Storage, Conversion, And

    Office of Scientific and Technical Information (OSTI)

    Utilization | OSTI, US Dept of Energy, Office of Scientific and Technical Information April 2013 Most Viewed Documents for Energy Storage, Conversion, And Utilization Science Subject Feed Seventh Edition Fuel Cell Handbook NETL (2004) 628 /> Continuously variable transmissions: theory and practice Beachley, N.H.; Frank, A.A. (null) 205 /> A study of lead-acid battery efficiency near top-of-charge and the impact on PV system design Stevens, J.W.; Corey, G.P. (1996) 173 /> Energy

  18. April 2013 Most Viewed Documents for Fission And Nuclear Technologies |

    Office of Scientific and Technical Information (OSTI)

    OSTI, US Dept of Energy, Office of Scientific and Technical Information April 2013 Most Viewed Documents for Fission And Nuclear Technologies Science Subject Feed Behavior of spent nuclear fuel in water pool storage Johnson, A.B. Jr. (null) 298 /> Estimation of gas leak rates through very small orifices and channels. [From sealed PuO/sub 2/ containers under accident conditions] Bomelburg, H.J. (null) 292 /> Graphite design handbook Ho, F.H. (1988) 216 /> System Definition and

  19. April 2013 Most Viewed Documents for Power Generation And Distribution |

    Office of Scientific and Technical Information (OSTI)

    OSTI, US Dept of Energy, Office of Scientific and Technical Information April 2013 Most Viewed Documents for Power Generation And Distribution Electric power high-voltage transmission lines: Design options, cost, and electric and magnetic field levels Stoffel, J.B.; Pentecost, E.D.; Roman, R.D.; Traczyk, P.A. (1994) 719 Seventh Edition Fuel Cell Handbook NETL (2004) 628 ASPEN Plus Simulation of CO2 Recovery Process Charles W. White III (2003) 343 Wet cooling towers: rule-of-thumb design and

  20. RVA: A Plugin for ParaView 3.14

    Energy Science and Technology Software Center (OSTI)

    2015-09-04

    RVA is a plugin developed for the 64-bit Windows version of the ParaView 3.14 visualization package. RVA is designed to provide support in the visualization and analysis of complex reservoirs being managed using multi-fluid EOR techniques. RVA, for Reservoir Visualization and Analysis, was developed at the University of Illinois at Urbana-Champaign, with contributions from the Illinois State Geological Survey, Department of Computer Science and National Center for Supercomputing Applications. RVA was designed to utilize andmore » enhance the state-of-the-art visualization capabilities within ParaView, readily allowing joint visualization of geologic framework and reservoir fluid simulation model results. Particular emphasis was placed on enabling visualization and analysis of simulation results highlighting multiple fluid phases, multiple properties for each fluid phase (including flow lines), multiple geologic models and multiple time steps. Additional advanced functionality was provided through the development of custom code to implement data mining capabilities. The built-in functionality of ParaView provides the capacity to process and visualize data sets ranging from small models on local desktop systems to extremely large models created and stored on remote supercomputers. The RVA plugin that we developed and the associated User Manual provide improved functionality through new software tools, and instruction in the use of ParaView-RVA, targeted to petroleum engineers and geologists in industry and research. The RVA web site (http://rva.cs.illinois.edu) provides an overview of functions, and the development web site (https://github.com/shaffer1/RVA) provides ready access to the source code, compiled binaries, user manual, and a suite of demonstration data sets. Key functionality has been included to support a range of reservoirs visualization and analysis needs, including: sophisticated connectivity analysis, cross sections through simulation results between selected wells, simplified volumetric calculations, global vertical exaggeration adjustments, ingestion of UTChem simulation results, ingestion of Isatis geostatistical framework models, interrogation of joint geologic and reservoir modeling results, joint visualization and analysis of well history files, location-targeted visualization, advanced correlation analysis, visualization of flow paths, and creation of static images and animations highlighting targeted reservoir features.« less

  1. Consumer Views on Transportation and Energy (Third Edition)

    SciTech Connect (OSTI)

    Kubik, M.

    2006-01-01

    This report has been assembled to provide the U.S. Department of Energy's (DOE's) Office of Energy Efficiency and Renewable Energy (EERE) with an idea of how the American public views various transportation, energy, and environmental issues. The data presented in this report have been drawn from multiple sources: surveys conducted by the Opinion Research Corporation (ORC) for the National Renewable Energy Laboratory (NREL) that are commissioned and funded by EERE, Gallup polls, news organization polls, surveys conducted by independent groups and academic institutions, and other sources.

  2. Ground control failures. A pictorial view of case studies

    SciTech Connect (OSTI)

    Peng, S.S.

    2007-07-01

    The book shows, in pictorial views, many forms and/or stages of types of failures in mines, for instance, cutter, roof falls, and cribs. In each case, the year of occurrence is stated in the beginning so that the environment or technological background under which it occurred are reflected. The narrative than begins with the mining and geological conditions, followed by a description of the ground control problems and recommended solutions and results, if any. The sections cover failure of pillars, roof falls, longwall, roof bolting, multiple-seam mining, floor heave, longwall, flooding and weathering of coal, old workings, and shortwall and thin-seam plow longwall.

  3. September 2013 Most Viewed Documents for Environmental Sciences | OSTI, US

    Office of Scientific and Technical Information (OSTI)

    Dept of Energy, Office of Scientific and Technical Information September 2013 Most Viewed Documents for Environmental Sciences Science Subject Feed Building a secondary containment system Broder, M.F. (1994) 59 /> Separation of heavy metals: Removal from industrial wastewaters and contaminated soil Peters, R.W.; Shem, L. (1993) 45 /> Test of a magnetic device for the amelioration of scale formation at Treatment Facility D Krauter, P.W., Harrar, J.E., Orloff, S.P., Bahowick, S.M. (1996)

  4. September 2013 Most Viewed Documents for Power Generation And Distribution

    Office of Scientific and Technical Information (OSTI)

    | OSTI, US Dept of Energy, Office of Scientific and Technical Information September 2013 Most Viewed Documents for Power Generation And Distribution Science Subject Feed Electric power high-voltage transmission lines: Design options, cost, and electric and magnetic field levels Stoffel, J.B.; Pentecost, E.D.; Roman, R.D.; Traczyk, P.A. (1994) 200 /> Wet cooling towers: rule-of-thumb design and simulation Leeper, S.A. (1981) 103 /> ASPEN Plus Simulation of CO2 Recovery Process Charles

  5. September 2015 Most Viewed Documents for Power Generation And Distribution

    Office of Scientific and Technical Information (OSTI)

    | OSTI, US Dept of Energy, Office of Scientific and Technical Information September 2015 Most Viewed Documents for Power Generation And Distribution Electric power high-voltage transmission lines: Design options, cost, and electric and magnetic field levels Stoffel, J.B.; Pentecost, E.D.; Roman, R.D.; Traczyk, P.A. (1994) 700 Wet cooling towers: rule-of-thumb design and simulation Leeper, S.A. (1981) 190 Load flow analysis: Base cases, data, diagrams, and results Portante, E.C.; Kavicky,

  6. January 2013 Most Viewed Documents for Fission And Nuclear Technologies |

    Office of Scientific and Technical Information (OSTI)

    OSTI, US Dept of Energy, Office of Scientific and Technical Information January 2013 Most Viewed Documents for Fission And Nuclear Technologies Laboratory studies of shear/leach processing of zircaloy clad metallic uranium reactor fuel Swanson, J.L.; Bray, L.A.; Kjarmo, H.E.; Ryan, J.L.; Matsuzaki, C.L.; Pitman, S.G.; Haberman, J.H. Working session 3: Tubing integrity Cueto-Felgueroso, C. [Tecnatom, S.A., San Sebastian de los Reyes, Madrid (Spain)]; Strosnider, J. [NRC, Washington, DC

  7. July 2013 Most Viewed Documents for Energy Storage, Conversion, And

    Office of Scientific and Technical Information (OSTI)

    Utilization | OSTI, US Dept of Energy, Office of Scientific and Technical Information July 2013 Most Viewed Documents for Energy Storage, Conversion, And Utilization Science Subject Feed Process Equipment Cost Estimation, Final Report H.P. Loh; Jennifer Lyons; Charles W. White, III (2002) 567 /> A study of lead-acid battery efficiency near top-of-charge and the impact on PV system design Stevens, J.W.; Corey, G.P. (1996) 142 /> Seventh Edition Fuel Cell Handbook NETL (2004) 133 />

  8. July 2013 Most Viewed Documents for Fission And Nuclear Technologies |

    Office of Scientific and Technical Information (OSTI)

    OSTI, US Dept of Energy, Office of Scientific and Technical Information July 2013 Most Viewed Documents for Fission And Nuclear Technologies Science Subject Feed Estimation of gas leak rates through very small orifices and channels. [From sealed PuO/sub 2/ containers under accident conditions] Bomelburg, H.J. (1977) 286 /> Graphite design handbook Ho, F.H. (1988) 136 /> Behavior of spent nuclear fuel in water pool storage Johnson, A.B. Jr. (1977) 123 /> Stress analysis and

  9. July 2013 Most Viewed Documents for Power Generation And Distribution |

    Office of Scientific and Technical Information (OSTI)

    OSTI, US Dept of Energy, Office of Scientific and Technical Information July 2013 Most Viewed Documents for Power Generation And Distribution Science Subject Feed Electric power high-voltage transmission lines: Design options, cost, and electric and magnetic field levels Stoffel, J.B.; Pentecost, E.D.; Roman, R.D.; Traczyk, P.A. (1994) 535 /> ASPEN Plus Simulation of CO2 Recovery Process Charles W. White III (2003) 165 /> Wet cooling towers: rule-of-thumb design and simulation Leeper,

  10. June 2014 Most Viewed Documents for Fission And Nuclear Technologies |

    Office of Scientific and Technical Information (OSTI)

    OSTI, US Dept of Energy, Office of Scientific and Technical Information June 2014 Most Viewed Documents for Fission And Nuclear Technologies Behavior of spent nuclear fuel in water pool storage Johnson, A.B. Jr. (1977) 78 Estimation of gas leak rates through very small orifices and channels. [From sealed PuO/sub 2/ containers under accident conditions] Bomelburg, H.J. (1977) 71 Review of thorium fuel reprocessing experience Brooksbank, R.E.; McDuffee, W.T.; Rainey, R.H. (1978) 70 Stress

  11. June 2014 Most Viewed Documents for Power Generation And Distribution |

    Office of Scientific and Technical Information (OSTI)

    OSTI, US Dept of Energy, Office of Scientific and Technical Information June 2014 Most Viewed Documents for Power Generation And Distribution Science Subject Feed Seventh Edition Fuel Cell Handbook NETL (2004) 118 /> Electric power high-voltage transmission lines: Design options, cost, and electric and magnetic field levels Stoffel, J.B.; Pentecost, E.D.; Roman, R.D.; Traczyk, P.A. (1994) 89 /> ASPEN Plus Simulation of CO2 Recovery Process Charles W. White III (2003) 85 /> Wet

  12. June 2015 Most Viewed Documents for Power Generation And Distribution |

    Office of Scientific and Technical Information (OSTI)

    OSTI, US Dept of Energy, Office of Scientific and Technical Information June 2015 Most Viewed Documents for Power Generation And Distribution Electric power high-voltage transmission lines: Design options, cost, and electric and magnetic field levels Stoffel, J.B.; Pentecost, E.D.; Roman, R.D.; Traczyk, P.A. (1994) 504 Wet cooling towers: rule-of-thumb design and simulation Leeper, S.A. (1981) 240 ASPEN Plus Simulation of CO2 Recovery Process Charles W. White III (2003) 160 Load flow

  13. March 2014 Most Viewed Documents for Fission And Nuclear Technologies |

    Office of Scientific and Technical Information (OSTI)

    OSTI, US Dept of Energy, Office of Scientific and Technical Information 4 Most Viewed Documents for Fission And Nuclear Technologies Science Subject Feed Behavior of spent nuclear fuel in water pool storage Johnson, A.B. Jr. (1977) 72 /> Peer-review study of the draft handbook for human-reliability analysis with emphasis on nuclear-power-plant applications, NUREG/CR-1278 Brune, R.L.; Weinstein, M.; Fitzwater, M.E. (1983) 67 /> Stress analysis and evaluation of a rectangular pressure

  14. March 2014 Most Viewed Documents for Power Generation And Distribution |

    Office of Scientific and Technical Information (OSTI)

    OSTI, US Dept of Energy, Office of Scientific and Technical Information 4 Most Viewed Documents for Power Generation And Distribution Science Subject Feed ASPEN Plus Simulation of CO2 Recovery Process Charles W. White III (2003) 112 /> Electric power high-voltage transmission lines: Design options, cost, and electric and magnetic field levels Stoffel, J.B.; Pentecost, E.D.; Roman, R.D.; Traczyk, P.A. (1994) 83 /> Seventh Edition Fuel Cell Handbook NETL (2004) 68 /> Load flow

  15. March 2015 Most Viewed Documents for Power Generation And Distribution |

    Office of Scientific and Technical Information (OSTI)

    OSTI, US Dept of Energy, Office of Scientific and Technical Information 5 Most Viewed Documents for Power Generation And Distribution Electric power high-voltage transmission lines: Design options, cost, and electric and magnetic field levels Stoffel, J.B.; Pentecost, E.D.; Roman, R.D.; Traczyk, P.A. (1994) 317 ASPEN Plus Simulation of CO2 Recovery Process Charles W. White III (2003) 254 Wet cooling towers: rule-of-thumb design and simulation Leeper, S.A. (1981) 234 Load flow analysis: Base

  16. Most Viewed Documents for Power Generation and Distribution: December 2014

    Office of Scientific and Technical Information (OSTI)

    | OSTI, US Dept of Energy, Office of Scientific and Technical Information Most Viewed Documents for Power Generation and Distribution: December 2014 Electric power high-voltage transmission lines: Design options, cost, and electric and magnetic field levels Stoffel, J.B.; Pentecost, E.D.; Roman, R.D.; Traczyk, P.A. (1994) 133 Seventh Edition Fuel Cell Handbook NETL (2004) 96 ASPEN Plus Simulation of CO2 Recovery Process Charles W. White III (2003) 84 Load flow analysis: Base cases, data,

  17. December 2015 Most Viewed Documents for Mathematics And Computing | OSTI,

    Office of Scientific and Technical Information (OSTI)

    US Dept of Energy, Office of Scientific and Technical Information December 2015 Most Viewed Documents for Mathematics And Computing Process Equipment Cost Estimation, Final Report H.P. Loh; Jennifer Lyons; Charles W. White, III (2002) 1446 Automotive vehicle sensors Sheen, S.H.; Raptis, A.C.; Moscynski, M.J. (1995) 373 A comparison of risk assessment techniques from qualitative to quantitative Altenbach, T.J. (1995) 365 Lecture notes for introduction to safety and health Biele, F. (1992) 324

  18. December 2015 Most Viewed Documents for Power Generation And Distribution |

    Office of Scientific and Technical Information (OSTI)

    OSTI, US Dept of Energy, Office of Scientific and Technical Information December 2015 Most Viewed Documents for Power Generation And Distribution Electric power high-voltage transmission lines: Design options, cost, and electric and magnetic field levels Stoffel, J.B.; Pentecost, E.D.; Roman, R.D.; Traczyk, P.A. (1994) 740 Load flow analysis: Base cases, data, diagrams, and results Portante, E.C.; Kavicky, J.A.; VanKuiken, J.C.; Peerenboom, J.P. (1997) 224 Wet cooling towers: rule-of-thumb

  19. T-704: RSA enVision Lets Remote Users View Files and Remote Authentica...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    RSA enVision Lets Remote Users View Files and Remote Authenticated Users Obtain Password T-704: RSA enVision Lets Remote Users View Files and Remote Authenticated Users Obtain...

  20. DOE Tour of Zero: The Isler Residence by Clifton View Homes ...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Isler Residence by Clifton View Homes DOE Tour of Zero: The Isler Residence by Clifton View Homes Addthis 1 of 23 This custom home built on Whidbey Island in Washington state by...

  1. A View of Environmental Justice at the U.S. Department of Energy |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy A View of Environmental Justice at the U.S. Department of Energy A View of Environmental Justice at the U.S. Department of Energy PDF icon A View of Environmental Justice at the U.S. Department of Energy More Documents & Publications A View of Environmental Justice at the U.S. Department of Energy (DOE, 2014) 2012 Independent Communication and Outreach Stakeholder Satisfaction Survey Environmental Justice Strategy

  2. Molecular structure in soil humic substances: The new view

    SciTech Connect (OSTI)

    Sutton, Rebecca; Sposito, Garrison

    2005-04-21

    A critical examination of published data obtained primarily from recent nuclear magnetic resonance spectroscopy, X-ray absorption near-edge structure spectroscopy, electrospray ionization-mass spectrometry, and pyrolysis studies reveals an evolving new view of the molecular structure of soil humic substances. According to the new view, humic substances are collections of diverse, relatively low molecular mass components forming dynamic associations stabilized by hydrophobic interactions and hydrogen bonds. These associations are capable of organizing into micellar structures in suitable aqueous environments. Humic components display contrasting molecular motional behavior and may be spatially segregated on a scale of nanometers. Within this new structural context, these components comprise any molecules intimately associated with a humic substance, such that they cannot be separated effectively by chemical or physical methods. Thus biomolecules strongly bound within humic fractions are by definition humic components, a conclusion that necessarily calls into question key biogeochemical pathways traditionally thought to be required for the formation of humic substances. Further research is needed to elucidate the intermolecular interactions that link humic components into supramolecular associations and to establish the pathways by which these associations emerge from the degradation of organic litter.

  3. Instrumentation requirements from the user's view. [For airbreathing hypersonic engines

    SciTech Connect (OSTI)

    Harsha, P.T.

    1988-01-01

    The use of combustor diagnostics is considered from the point of view of demonstration of performance of an airbreathing hypersonic engine. The basic need is seen to be that of providing the data necessary to verify performance predictions for the engine as installed in the airplane. This necessitates the use of a diagnostics capability that can provide the inputs required by the computational analyses that will be used to assess this performance. Because of the cost of ground test facilities, a premium is placed on measurement technique reliability and redundancy of instrumentation. A mix of nonintrusive optical techniques and probe-based measurements is seen to be the best approach using current diagnostics capability; one such instrument mix is outlined for a ramjet/scramjet test program. 11 references.

  4. Growth plate closure: Apex view on bone scan

    SciTech Connect (OSTI)

    Giles, P.H.; Trochei, M.; Yeates, K.

    1984-01-01

    Angular deformities of the extremities in children following premature closure of the growth plate are well known. The deformities depend on the position of an osseus bridge which forms between the epiphysis and metaphysis. Several surgical procedures including resection of the osseus bridge have been described, however, delineation of the site of fusion is difficult to define. The commonest site of growth plate arrest is the distal femoral or proximal tibial growth plate. A new technique using the bone scan has been developed which accurately defines the area and position of these osseus bridges. Two hours after injection of technetium 99m methylene diphosphonate apex views of the affected distal femoral growth plate were performed. The knee was flexed into its smallest angle. Using a pinhole collimator the gamma camera was angled to face the affected growth plate end on. The image was collected onto computer and analysed by: (I) regions of interest over segments of the growth plate to calculate the relative area of total growth plate affected: (II) generating histograms: (III) thresholding or performing isocontours to accentuate abnormal areas. The growth plate is normally uniformly increased when compared to the normal shaft of the bone. Fusion across the plate appears as an area of diminished uptake. The apex view gives a unique functional map of the growth plate such that abnormal areas are displayed, and the site, size and position of osseus fusion obtained. The technique has the potential for determining the metabolic activity of the growth plate before and after surgery. Serial studies will allow assessment of regneration of the plate and reformation of new osseus bridges.

  5. The effects of interstitial atoms H and B on magnetic properties and magnetocaloric effect in LaFe{sub 11.5}Al{sub 1.5} compound

    SciTech Connect (OSTI)

    Zhang, D. K.; Zhao, J. L.; Shen, J.; Zhang, H. G.; Yue, M.

    2014-05-14

    The changes in magnetic properties of LaFe{sub 11.5}Al{sub 1.5}H{sub x} and LaFe{sub 11.5}Al{sub 1.5}B{sub y} have been investigated. By introducing interstitial atoms H or B, the magnetic ground state is changed from the antiferromagnetic to the ferromagnetic state, accompanied by significant increases in the saturated magnetization (Ms) and the Curie temperature (T{sub C}). An attractive feature is that the magnetic transition from the second-order to the weakly first-order with increasing hydrogen content compared to the magnetic transition from the weakly first-order to the second-order with increasing boron content. The maximum magnetic entropy change (−ΔS{sub M}) under a field change of 0–5 T increases from 10.1 J/kg · K for hydrogen content x = 0.12 to 12.3 J/kg · K for x = 1.3, while decreases from 9.6 J/kg · K for boron content y = 0.1 to 9.2 J/kg · K for y = 0.3.

  6. TH-E-17A-10: Markerless Lung Tumor Tracking Based On Beams Eye View EPID Images

    SciTech Connect (OSTI)

    Chiu, T; Kearney, V; Liu, H; Jiang, L; Foster, R; Mao, W; Rozario, T; Bereg, S; Klash, S

    2014-06-15

    Purpose: Dynamic tumor tracking or motion compensation techniques have proposed to modify beam delivery following lung tumor motion on the flight. Conventional treatment plan QA could be performed in advance since every delivery may be different. Markerless lung tumor tracking using beams eye view EPID images provides a best treatment evaluation mechanism. The purpose of this study is to improve the accuracy of the online markerless lung tumor motion tracking method. Methods: The lung tumor could be located on every frame of MV images during radiation therapy treatment by comparing with corresponding digitally reconstructed radiograph (DRR). A kV-MV CT corresponding curve is applied on planning kV CT to generate MV CT images for patients in order to enhance the similarity between DRRs and MV treatment images. This kV-MV CT corresponding curve was obtained by scanning a same CT electron density phantom by a kV CT scanner and MV scanner (Tomotherapy) or MV CBCT. Two sets of MV DRRs were then generated for tumor and anatomy without tumor as the references to tracking the tumor on beams eye view EPID images. Results: Phantom studies were performed on a Varian TrueBeam linac. MV treatment images were acquired continuously during each treatment beam delivery at 12 gantry angles by iTools. Markerless tumor tracking was applied with DRRs generated from simulated MVCT. Tumors were tracked on every frame of images and compared with expected positions based on programed phantom motion. It was found that the average tracking error were 2.3 mm. Conclusion: This algorithm is capable of detecting lung tumors at complicated environment without implanting markers. It should be noted that the CT data has a slice thickness of 3 mm. This shows the statistical accuracy is better than the spatial accuracy. This project has been supported by a Varian Research Grant.

  7. Gantry for medical particle therapy facility

    DOE Patents [OSTI]

    Trbojevic, Dejan

    2012-05-08

    A particle therapy gantry for delivering a particle beam to a patient includes a beam tube having a curvature defining a particle beam path and a plurality of fixed field magnets sequentially arranged along the beam tube for guiding the particle beam along the particle path. In a method for delivering a particle beam to a patient through a gantry, a particle beam is guided by a plurality of fixed field magnets sequentially arranged along a beam tube of the gantry and the beam is alternately focused and defocused with alternately arranged focusing and defocusing fixed field magnets.

  8. Gantry for medical particle therapy facility

    DOE Patents [OSTI]

    Trbojevic, Dejan

    2013-04-23

    A particle therapy gantry for delivering a particle beam to a patient includes a beam tube having a curvature defining a particle beam path and a plurality of superconducting, variable field magnets sequentially arranged along the beam tube for guiding the particle beam along the particle path. In a method for delivering a particle beam to a patient through a gantry, a particle beam is guided by a plurality of variable field magnets sequentially arranged along a beam tube of the gantry and the beam is alternately focused and defocused with alternately arranged focusing and defocusing variable field magnets.

  9. Acceleration Of Wound Healing Ny Photodynamic Therapy

    DOE Patents [OSTI]

    Hasan, Tayyaba; Hamblin, Michael R.; Trauner, Kenneth

    2000-08-22

    Disclosed is a method for accelerating wound healing in a mammal. The method includes identifying an unhealed wound site or partially-healed wound site in a mammal; administering a photosensitizer to the mammal; waiting for a time period wherein the photosensitizer reaches an effective tissue concentration at the wound site; and photoactivating the photosensitizer at the wound site. The dose of photodynamic therapy is selected to stimulate the production of one or more growth factor by cells at the wound site, without causing tissue destruction.

  10. Oct. 25 Lecture Highlights Treatment Technology of HU's Proton Therapy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Institute | Jefferson Lab Oct. 25 Lecture Highlights Treatment Technology of HU's Proton Therapy Institute Oct. 25 Lecture Highlights Treatment Technology of HU's Proton Therapy Institute Cynthia Keppel Hampton University Proton Therapy Institute Scientific and Technical Director, Cynthia Keppel, will present a public lecture titled "Accelerating Protons to Save Lives" on Oct. 25 at Jefferson Lab in Newport News. NEWPORT NEWS, Va., Sept. 29, 2011 - Jefferson Lab's 2011 Fall Science

  11. Metalloporphyrins and their uses as radiosensitizers for radiation therapy

    DOE Patents [OSTI]

    Miura, Michiko; Slatkin, Daniel N.

    2004-07-06

    The present invention covers radiosensitizers containing as an active ingredient halogenated derivatives of boronated porphyrins containing multiple carborane cages having the structure ##STR1## which selectively accumulate in neoplastic tissue within the irradiation volume and thus can be used in cancer therapies including, but not limited to, boron neutron--capture therapy and photodynamic therapy. The present invention also covers methods for using these radiosensitizers in tumor imaging and cancer treatment.

  12. Methods for implementing microbeam radiation therapy

    DOE Patents [OSTI]

    Dilmanian, F. Avraham; Morris, Gerard M.; Hainfeld, James F.

    2007-03-20

    A method of performing radiation therapy includes delivering a therapeutic dose such as X-ray only to a target (e.g., tumor) with continuous broad beam (or in-effect continuous) using arrays of parallel planes of radiation (microbeams/microplanar beams). Microbeams spare normal tissues, and when interlaced at a tumor, form a broad-beam for tumor ablation. Bidirectional interlaced microbeam radiation therapy (BIMRT) uses two orthogonal arrays with inter-beam spacing equal to beam thickness. Multidirectional interlaced MRT (MIMRT) includes irradiations of arrays from several angles, which interleave at the target. Contrast agents, such as tungsten and gold, are administered to preferentially increase the target dose relative to the dose in normal tissue. Lighter elements, such as iodine and gadolinium, are used as scattering agents in conjunction with non-interleaving geometries of array(s) (e.g., unidirectional or cross-fired (intersecting) to generate a broad beam effect only within the target by preferentially increasing the valley dose within the tumor.

  13. Reducing the uncertainties in particle therapy

    SciTech Connect (OSTI)

    Oancea, C.; Shipulin, K. N.; Mytsin, G. V.; Luchin, Y. I.

    2015-02-24

    The use of fundamental Nuclear Physics in Nuclear Medicine has a significant impact in the fight against cancer. Hadrontherapy is an innovative cancer radiotherapy method using nuclear particles (protons, neutrons and ions) for the treatment of early and advanced tumors. The main goal of proton therapy is to deliver high radiation doses to the tumor volume with minimal damage to healthy tissues and organs. The purpose of this work was to investigate the dosimetric errors in clinical proton therapy dose calculation due to the presence of metallic implants in the treatment plan, and to determine the impact of the errors. The results indicate that the errors introduced by the treatment planning systems are higher than 10% in the prediction of the dose at isocenter when the proton beam is passing directly through a metallic titanium alloy implant. In conclusion, we recommend that pencil-beam algorithms not be used when planning treatment for patients with titanium alloy implants, and to consider implementing methods to mitigate the effects of the implants.

  14. Cytometric Therapies for Cell Delivery - Energy Innovation Portal

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Advanced Materials Advanced Materials Find More Like This Return to Search Cytometric Therapies for Cell Delivery Maximizing Efficacy of Cell Delivery Oak Ridge National Laboratory ...

  15. Radioisotopes for Medical Diagnostics and Cancer Therapy at BNL...

    Office of Science (SC) Website

    Radioisotopes for Medical Diagnostics and Cancer Therapy at BNL Nuclear Physics (NP) NP Home About Research Facilities Science Highlights Benefits of NP Applications of Nuclear ...

  16. Accessing and Viewing NETL Solicitations/Funding Opportunity Announcements on FedConnect

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Accessing NETL Solicitations/Funding Opportunity Announcements in FedConnect In the Internet Explorer browser, enter the FedConnect URL www.FedConnect.net On the Main Page, click on Search Public Opportunities and Awards Under Search Criteria, select Issuing Office and type in NETL. Click on Search. Click the hyperlink under the title to view. Click on Body under Solicitation to view the solicitation/announcement instructions. To view Amendments to the solicitation/announcement, click on Body

  17. T-538: HP OpenView Storage Data Protector Bug Lets Remote Users Execute Arbitrary Code

    Broader source: Energy.gov [DOE]

    A vulnerability was reported in HP OpenView Storage Data Protector. A remote user can execute arbitrary code on the target system.

  18. T-643: HP OpenView Storage Data Protector Unspecified Code Execution Vulnerability

    Broader source: Energy.gov [DOE]

    A vulnerability has been reported in HP OpenView Storage Data Protector, which can be exploited by malicious people to compromise a vulnerable system.

  19. Intraoperative radiation therapy in recurrent ovarian cancer

    SciTech Connect (OSTI)

    Yap, O.W. Stephanie . E-mail: stbeast@stanford.edu; Kapp, Daniel S.; Teng, Nelson N.H.; Husain, Amreen

    2005-11-15

    Purpose: To evaluate disease outcomes and complications in patients with recurrent ovarian cancer treated with cytoreductive surgery and intraoperative radiation therapy (IORT). Methods and Materials: A retrospective study of 24 consecutive patients with ovarian carcinoma who underwent secondary cytoreduction and intraoperative radiation therapy at our institution between 1994 and 2002 was conducted. After optimal cytoreductive surgery, IORT was delivered with orthovoltage X-rays (200 kVp) using individually sized and beveled cone applications. Outcomes measures were local control of disease, progression-free interval, overall survival, and treatment-related complications. Results: Of these 24 patients, 22 were available for follow-up analysis. Additional treatment at the time of and after IORT included whole abdominopelvic radiation, 9; pelvic or locoregional radiation, 5; chemotherapy, 6; and no adjuvant treatment, 2. IORT doses ranged from 9-14 Gy (median, 12 Gy). The anatomic sites treated were pelvis (sidewalls, vaginal cuff, presacral area, anterior pubis), para-aortic and paracaval lymph node beds, inguinal region, or porta hepatitis. At a median follow-up of 24 months, 5 patients remain free of disease, whereas 17 patients have recurred, of whom 4 are alive with disease and 13 died from disease. Five patients recurred within the radiation fields for a locoregional relapse rate of 32% and 12 patients recurred at distant sites with a median time to recurrence of 13.7 months. Five-year overall survival was 22% with a median survival of 26 months from time of IORT. Nine patients (41%) experienced Grade 3 toxicities from their treatments. Conclusion: In carefully selected patients with locally recurrent ovarian cancer, combined IORT and tumor reductive surgery is reasonably tolerated and may contribute to achieving local control and disease palliation.

  20. Endoscopic Electron-Beam Cancer Therapy | Argonne National Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Endoscopic Electron-Beam Cancer Therapy Technology available for licensing: A successful and cost-effective means of treating cancer in previously inoperable or radiation-sensitive areas of the body. Cost-effective Can treat cancer in inoperable or radiation-sensitive areas PDF icon e-beam_cancer_therapy

  1. Thiourea derivatives, methods of their preparation and their use in neutron capture therapy of malignant melanoma

    DOE Patents [OSTI]

    Gabel, Detlef

    1991-01-01

    The present invention pertains to boron containing thiouracil derivatives, their method of preparations, and their use in the therapy of malignant melanoma using boron neutron capture therapy.

  2. Boron containing compounds and their preparation and use in neutron capture therapy

    DOE Patents [OSTI]

    Gabel, Detlef

    1992-01-01

    The present invention pertains to boron containing thiouracil derivatives, their method of preparations, and their use in the therapy of malignant melanoma using boron neutron capture therapy.

  3. Cold atmospheric plasma in cancer therapy

    SciTech Connect (OSTI)

    Keidar, Michael; Shashurin, Alex; Volotskova, Olga; Ann Stepp, Mary; Srinivasan, Priya; Sandler, Anthony; Trink, Barry

    2013-05-15

    Recent progress in atmospheric plasmas has led to the creation of cold plasmas with ion temperature close to room temperature. This paper outlines recent progress in understanding of cold plasma physics as well as application of cold atmospheric plasma (CAP) in cancer therapy. Varieties of novel plasma diagnostic techniques were developed recently in a quest to understand physics of CAP. It was established that the streamer head charge is about 10{sup 8} electrons, the electrical field in the head vicinity is about 10{sup 7} V/m, and the electron density of the streamer column is about 10{sup 19} m{sup ?3}. Both in-vitro and in-vivo studies of CAP action on cancer were performed. It was shown that the cold plasma application selectively eradicates cancer cells in-vitro without damaging normal cells and significantly reduces tumor size in-vivo. Studies indicate that the mechanism of action of cold plasma on cancer cells is related to generation of reactive oxygen species with possible induction of the apoptosis pathway. It is also shown that the cancer cells are more susceptible to the effects of CAP because a greater percentage of cells are in the S phase of the cell cycle.

  4. Periodontium destruction associated with oncology therapy. Five case reports

    SciTech Connect (OSTI)

    Wright, W.E.

    1987-08-01

    Radiation treatment to the head and neck and cytotoxic chemotherapy can produce deleterious side effects to the periodontium that are generally transient in nature, reversible, and do not result in permanently visible defects. However, combinations of the malignant disease itself, the direct and indirect effects of medical therapy and associated oral infections, along with local trauma can lead to periodontal tissue destruction with resulting permanent architectural defects. Five case reports illustrate destructive alterations of the periodontium that were associated with oncology therapy. Proposed guidelines for periodontal treatment of compromised individuals undergoing oncology therapies are suggested.

  5. Target tracking using DMLC for volumetric modulated arc therapy: A simulation study

    SciTech Connect (OSTI)

    Sun Baozhou; Rangaraj, Dharanipathy; Papiez, Lech; Oddiraju, Swetha; Yang Deshan; Li, H. Harold

    2010-12-15

    Purpose: Target tracking using dynamic multileaf collimator (DMLC) is a promising approach for intrafraction motion management in radiation therapy. The purpose of this work is to develop a DMLC tracking algorithm capable of delivering volumetric-modulated arc therapy (VMAT) to the targets that experience two-dimensional (2D) rigid motion in the beam's eye view. Methods: The problem of VMAT delivery to moving targets is formulated as a control problem with constraints. The relationships between gantry speed, gantry acceleration, MLC leaf-velocity, dose rate, and target motion are derived. An iterative search algorithm is developed to find numerical solutions for efficient delivery of a specific VMAT plan to the moving target using 2D DMLC tracking. The delivery of five VMAT lung plans is simulated. The planned and delivered fluence maps in the target-reference frame are calculated and compared. Results: The simulation demonstrates that the 2D tracking algorithm is capable of delivering the VMAT plan to a moving target fast and accurately without violating the machine constraints and the integrity of the treatment plan. The average delivery time is only 29 s longer than that of no-tracking delivery, 101 versus 72 s, respectively. The fluence maps are normalized to 200 MU and the average root-mean-square error between the desired and the delivered fluence is 2.1 MU, compared to 14.8 MU for no-tracking and 3.6 MU for one-dimensional tracking. Conclusions: A locally optimal MLC tracking algorithm for VMAT delivery is proposed, aiming at shortest delivery time while maintaining treatment plan invariant. The inconsequential increase of treatment time due to DMLC tracking is clinically desirable, which makes VMAT with DMLC tracking attractive in treating moving tumors.

  6. View the Apps for Vehicles Phase One Submissions | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    View the Apps for Vehicles Phase One Submissions View the Apps for Vehicles Phase One Submissions January 24, 2013 - 11:13am Addthis 9 of the 37 entries for the Apps for Vehicles competition. 9 of the 37 entries for the Apps for Vehicles competition. Ian Kalin Director of the Energy Data Initiative How can I participate? Visit the competition website to view the submitted ideas. Starting on March 15, you'll be able to vote for your favorite completed apps. Apps for Vehicles The Open Data

  7. DOE Tour of Zero: Marine Drive by Clifton View Homes | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Marine Drive by Clifton View Homes DOE Tour of Zero: Marine Drive by Clifton View Homes Addthis 1 of 10 Clifton View Homes built this 2,408-square-foot zero energy home in Coupeville, Washington, to the performance criteria of the U.S. Department of Energy Zero Energy Ready Home (ZERH) program. 2 of 10 The ultra-efficient home has 7.84 kW of solar electric panels on the roof, which contribute to zero utility bills for the homeowners. The roof is built with structural insulated panels (SIPs) that

  8. DOE Tour of Zero: Marine Drive by Clifton View Homes | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Marine Drive by Clifton View Homes DOE Tour of Zero: Marine Drive by Clifton View Homes 1 of 10 Clifton View Homes built this 2,408-square-foot zero energy home in Coupeville, Washington, to the performance criteria of the U.S. Department of Energy Zero Energy Ready Home (ZERH) program. 2 of 10 The ultra-efficient home has 7.84 kW of solar electric panels on the roof, which contribute to zero utility bills for the homeowners. The roof is built with structural insulated panels (SIPs) that are

  9. DOE Tour of Zero: Port Hadlock by Clifton View Homes | Department of Energy

    Energy Savers [EERE]

    Port Hadlock by Clifton View Homes DOE Tour of Zero: Port Hadlock by Clifton View Homes Addthis 1 of 10 Clifton View Homes built this 1,784-square-foot zero energy home in Port Hadlock, Washington, to the performance criteria of the U.S. Department of Energy Zero Energy Ready Home (ZERH) program. 2 of 10 The ultra-efficient home has 7.56 kW of solar electric panels on the roof that help it to achieve annual energy bills of $35. The solar panels are installed on the durable, fire-resistant

  10. Optic for an endoscope/borescope having high resolution and narrow field of view

    DOE Patents [OSTI]

    Stone, Gary F.; Trebes, James E.

    2003-10-28

    An optic having optimized high spatial resolution, minimal nonlinear magnification distortion while at the same time having a limited chromatic focal shift or chromatic aberrations. The optic located at the distal end of an endoscopic inspection tool permits a high resolution, narrow field of view image for medical diagnostic applications, compared to conventional optics for endoscopic instruments which provide a wide field of view, low resolution image. The image coverage is over a narrow (<20 degrees) field of view with very low optical distortion (<5% pin cushion or barrel distortion. The optic is also optimized for best color correction as well as to aid medical diagnostics.

  11. View TEDxCERN in Jefferson Lab Auditorium on Sept. 24 | Jefferson Lab

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    View TEDxCERN in Jefferson Lab Auditorium on Sept. 24 View TEDxCERN in Jefferson Lab Auditorium on Sept. 24 NEWPORT NEWS, Va. - Jefferson Lab will stream TEDxCERN 2014 on the big screen in the CEBAF Center auditorium on Sept. 24, from 7:30 a.m. - 1:30 p.m. EDT. University and college faculty and students affiliated with Jefferson Lab are invited to attend all or any part of the event viewing. TED talks are brief conversations - each lasting 18 minutes or less - that bring together people from

  12. Radiation Therapy for Neovascular Age-related Macular Degeneration

    SciTech Connect (OSTI)

    Kishan, Amar U.; Modjtahedi, Bobeck S.; Morse, Lawrence S.; Lee, Percy

    2013-03-01

    In the enormity of the public health burden imposed by age-related macular degeneration (ARMD), much effort has been directed toward identifying effective and efficient treatments. Currently, anti-vascular endothelial growth factor (VEGF) injections have demonstrated considerably efficacy in treating neovascular ARMD, but patients require frequent treatment to fully benefit. Here, we review the rationale and evidence for radiation therapy of ARMD. The results of early photon external beam radiation therapy are included to provide a framework for the sequential discussion of evidence for the usage of stereotactic radiation therapy, proton therapy, and brachytherapy. The evidence suggests that these 3 modern modalities can provide a dose-dependent benefit in the treatment of ARMD. Most importantly, preliminary data suggest that all 3 can be used in conjunction with anti-VEGF therapeutics, thereby reducing the frequency of anti-VEGF injections required to maintain visual acuity.

  13. Once-Daily Radiation Therapy for Inflammatory Breast Cancer

    SciTech Connect (OSTI)

    Brown, Lindsay; Harmsen, William; Blanchard, Miran; Goetz, Matthew; Jakub, James; Mutter, Robert; Petersen, Ivy; Rooney, Jessica; Stauder, Michael; Yan, Elizabeth; Laack, Nadia

    2014-08-01

    Purpose: Inflammatory breast cancer (IBC) is a rare and aggressive breast cancer variant treated with multimodality therapy. A variety of approaches intended to escalate the intensity and efficacy of radiation therapy have been reported, including twice-daily radiation therapy, dose escalation, and aggressive use of bolus. Herein, we examine our outcomes for patients treated with once-daily radiation therapy with aggressive bolus utilization, focusing on treatment technique. Methods and Materials: A retrospective review of patients with nonmetastatic IBC treated from January 1, 2000, through December 31, 2010, was performed. Locoregional control (LRC), disease-free survival (DFS), overall survival (OS) and predictors thereof were assessed. Results: Fifty-two women with IBC were identified, 49 (94%) of whom were treated with neoadjuvant chemotherapy. All underwent mastectomy followed by adjuvant radiation therapy. Radiation was delivered in once-daily fractions of 1.8 to 2.25 Gy (median, 2 Gy). Patients were typically treated with daily 1-cm bolus throughout treatment, and 33 (63%) received a subsequent boost to the mastectomy scar. Five-year Kaplan Meier survival estimates for LRC, DFS, and OS were 81%, 56%, and 64%, respectively. Locoregional recurrence was associated with poorer OS (P<.001; hazard ratio [HR], 4.1). Extracapsular extension was associated with worse LRC (P=.02), DFS (P=.007), and OS (P=.002). Age greater than 50 years was associated with better DFS (P=.03). Pathologic complete response was associated with a trend toward improved LRC (P=.06). Conclusions: Once-daily radiation therapy with aggressive use of bolus for IBC results in outcomes consistent with previous reports using various intensified radiation therapy regimens. LRC remains a challenge despite modern systemic therapy. Extracapsular extension, age ≤50 years, and lack of complete response to chemotherapy appear to be associated with worse outcomes. Novel strategies are needed in IBC, particularly among these subsets of patients.

  14. Assessing the feasibility of volumetric-modulated arc therapy using

    Office of Scientific and Technical Information (OSTI)

    simultaneous integrated boost (SIB-VMAT): An analysis for complex head-neck, high-risk prostate and rectal cancer cases (Journal Article) | SciTech Connect Assessing the feasibility of volumetric-modulated arc therapy using simultaneous integrated boost (SIB-VMAT): An analysis for complex head-neck, high-risk prostate and rectal cancer cases Citation Details In-Document Search Title: Assessing the feasibility of volumetric-modulated arc therapy using simultaneous integrated boost (SIB-VMAT):

  15. Fast Monte Carlo for radiation therapy: the PEREGRINE Project (Conference)

    Office of Scientific and Technical Information (OSTI)

    | SciTech Connect Conference: Fast Monte Carlo for radiation therapy: the PEREGRINE Project Citation Details In-Document Search Title: Fast Monte Carlo for radiation therapy: the PEREGRINE Project × You are accessing a document from the Department of Energy's (DOE) SciTech Connect. This site is a product of DOE's Office of Scientific and Technical Information (OSTI) and is provided as a public service. Visit OSTI to utilize additional information resources in energy science and technology.

  16. Particles from Comet 81P/Wild 2 Viewed by ALS Microscopes

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Wild 2 Viewed by ALS Microscopes Print NASA's 200-million, seven-year-long Stardust mission returned to Earth thousands of tiny particles snagged from the coma of comet 81PWild...

  17. DOE Zero Energy Ready Home Case Study: Clifton View Homes, Coupeville...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    DOE Zero Energy Ready Home Case Study: Clifton View Homes, Coupeville, WA, Systems Home Case study of a DOE Zero Energy Ready Home on Whidbey Island, WA, that scored HERS 45 ...

  18. Particles from Comet 81P/Wild 2 Viewed by ALS Microscopes

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Particles from Comet 81PWild 2 Viewed by ALS Microscopes Print NASA's 200-million, seven-year-long Stardust mission returned to Earth thousands of tiny particles snagged from the...

  19. GPU-based Scalable Volumetric Reconstruction for Multi-view Stereo

    SciTech Connect (OSTI)

    Kim, H; Duchaineau, M; Max, N

    2011-09-21

    We present a new scalable volumetric reconstruction algorithm for multi-view stereo using a graphics processing unit (GPU). It is an effectively parallelized GPU algorithm that simultaneously uses a large number of GPU threads, each of which performs voxel carving, in order to integrate depth maps with images from multiple views. Each depth map, triangulated from pair-wise semi-dense correspondences, represents a view-dependent surface of the scene. This algorithm also provides scalability for large-scale scene reconstruction in a high resolution voxel grid by utilizing streaming and parallel computation. The output is a photo-realistic 3D scene model in a volumetric or point-based representation. We demonstrate the effectiveness and the speed of our algorithm with a synthetic scene and real urban/outdoor scenes. Our method can also be integrated with existing multi-view stereo algorithms such as PMVS2 to fill holes or gaps in textureless regions.

  20. June 2014 Most Viewed Documents for Physics | OSTI, US Dept of...

    Office of Scientific and Technical Information (OSTI)

    June 2014 Most Viewed Documents for Physics Science Subject Feed Plastic Gamma Sensors: An ... (1983) 25 > HANDBOOK OF ACCELERATOR PHYSICS AND ENGINEERING; SECTIONS 2.7.1-2.7.5 AND ...

  1. June 2015 Most Viewed Documents for Physics | OSTI, US Dept of...

    Office of Scientific and Technical Information (OSTI)

    June 2015 Most Viewed Documents for Physics Cathodic arc plasma deposition Anders, Andre ... M. (1991) 38 HANDBOOK OF ACCELERATOR PHYSICS AND ENGINEERING; SECTIONS 2.7.1-2.7.5 AND ...

  2. July 2013 Most Viewed Documents for Physics | OSTI, US Dept of...

    Office of Scientific and Technical Information (OSTI)

    July 2013 Most Viewed Documents for Physics Science Subject Feed Lithium literature review: lithium's properties and interactions Jeppson, D.W.; Ballif, J.L.; Yuan, W.W.; Chou, ...

  3. DOE Zero Energy Ready Home Case Study: Clifton View Homes, Marine...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    and passive design; air-to-water heatpump, fresh air intake with fan, triple-pane windows, 100% LED. PDF icon DOE Zero Energy Ready Home Case Study: Clifton View Homes, ...

  4. TU-C-BRE-04: 3D Gel Dosimetry Using ViewRay On-Board MR Scanner: A Feasibility Study

    SciTech Connect (OSTI)

    Zhang, L; Du, D; Green, O; Rodriguez, V; Wooten, H; Xiao, Z; Yang, D; Hu, Y; Li, H

    2014-06-15

    Purpose: MR based 3D gel has been proposed for radiation therapy dosimetry. However, access to MR scanner has been one of the limiting factors for its wide acceptance. Recent commercialization of an on-board MR-IGRT device (ViewRay) may render the availability issue less of a concern. This work reports our attempts to simulate MR based dose measurement accuracy on ViewRay using three different gels. Methods: A spherical BANG gel dosimeter was purchased from MGS Research. Cylindrical MAGIC gel and Fricke gel were fabricated in-house according to published recipes. After irradiation, BANG and MAGIC were imaged using a dual-echo spin echo sequence for T2 measurement on a Philips 1.5T MR scanner, while Fricke gel was imaged using multiple spin echo sequences. Difference between MR measured and TPS calculated dose was defined as noise. The noise power spectrum was calculated and then simulated for the 0.35 T magnetic field associated with ViewRay. The estimated noise was then added to TG-119 test cases to simulate measured dose distributions. Simulated measurements were evaluated against TPS calculated doses using gamma analysis. Results: Given same gel, sequence and coil setup, with a FOV of 180×90×90 mm3, resolution of 3×3×3 mm3, and scanning time of 30 minutes, the simulated measured dose distribution using BANG would have a gamma passing rate greater than 90% (3%/3mm and absolute). With a FOV 180×90×90 mm3, resolution of 4×4×5 mm3, and scanning time of 45 minutes, the simulated measuremened dose distribution would have a gamma passing rate greater than 97%. MAGIC exhibited similar performance while Fricke gel was inferior due to much higher noise. Conclusions: The simulation results demonstrated that it may be feasible to use MAGIC and BANG gels for 3D dose verification using ViewRay low-field on-board MRI scanner.

  5. A View of Environmental Justice at the U.S. Department of Energy (DOE,

    Energy Savers [EERE]

    2014) | Department of Energy A View of Environmental Justice at the U.S. Department of Energy (DOE, 2014) A View of Environmental Justice at the U.S. Department of Energy (DOE, 2014) Executive Order 12898 requires each federal agency to make environmental justice part of its mission by identifying and addressing, as appropriate, disproportionally high and adverse human health or environmental effects of its program, policies, and activities on minority populations and low-income populations.

  6. New Window Technology Saves Energy and the View | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Window Technology Saves Energy and the View New Window Technology Saves Energy and the View November 5, 2013 - 3:55pm Addthis Researchers at the Energy Department's National Renewable Energy Laboratory are developing innovative new window technology that helps improve occupants' comfort and cuts energy use. | Photo courtesy of Pat Corkery, NREL. Researchers at the Energy Department's National Renewable Energy Laboratory are developing innovative new window technology that helps improve

  7. DOE Seeks Public Views On How Best To Streamline Existing Regulations |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Public Views On How Best To Streamline Existing Regulations DOE Seeks Public Views On How Best To Streamline Existing Regulations January 31, 2011 - 5:53pm Addthis The Department of Energy today announced two immediate steps to implement the Obama Administration's Executive Order on Improving Regulation and Regulatory Review, which directs federal agencies to review existing regulations and determine whether they are still necessary and crafted effectively to solve

  8. Microsoft Word - A Systems View of the Modern Grid_Final_v2_0.doc

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    V2.0 The NETL Modern Grid Initiative A SYSTEMS VIEW OF THE MODERN GRID Conducted by the National Energy Technology Laboratory for the U.S. Department of Energy Office of Electricity Delivery and Energy Reliability January 2007 Office of Electricity Delivery and Energy Reliability Page 1 v2.0 A Systems View of the Modern Grid TABLE OF CONTENTS Table of Contents ..................................................................................... 1 Executive Summary

  9. Viewing spin structures with soft x-ray microscopy (Journal Article) |

    Office of Scientific and Technical Information (OSTI)

    SciTech Connect Viewing spin structures with soft x-ray microscopy Citation Details In-Document Search Title: Viewing spin structures with soft x-ray microscopy The spin of the electron and its associated magnetic moment marks the basic unit for magnetic properties of matter. Magnetism, in particular ferromagnetism and antiferromagnetism is described by a collective order of these spins, where the interaction between individual spins reflects a competition between exchange, anisotropy and

  10. Biogas From Municipal WWTPs: Fuel Cells Viewed as a Value Proposition |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy From Municipal WWTPs: Fuel Cells Viewed as a Value Proposition Biogas From Municipal WWTPs: Fuel Cells Viewed as a Value Proposition Presentation about the value proposition for biogas from waste water treatment plants. Presented by Steve Hamilton, SCS Energy, at the NREL/DOE Biogas and Fuel Cells Workshop held June 11-13, 2012, in Golden, Colorado. PDF icon june2012_biogas_workshop_hamilton.pdf More Documents & Publications Biogas and Fuel Cells Workshop Summary

  11. Biochemical Response to Androgen Deprivation Therapy Before External Beam Radiation Therapy Predicts Long-term Prostate Cancer Survival Outcomes

    SciTech Connect (OSTI)

    Zelefsky, Michael J.; Gomez, Daniel R.; Polkinghorn, William R.; Pei, Xin; Kollmeier, Marisa

    2013-07-01

    Purpose: To determine whether the response to neoadjuvant androgen deprivation therapy (ADT) defined by a decline in prostate-specific antigen (PSA) to nadir values is associated with improved survival outcomes after external beam radiation therapy (EBRT) for prostate cancer. Methods and Materials: One thousand forty-five patients with localized prostate cancer were treated with definitive EBRT in conjunction with neoadjuvant and concurrent ADT. A 6-month course of ADT was used (3 months during the neoadjuvant phase and 2 to 3 months concurrently with EBRT). The median EBRT prescription dose was 81 Gy using a conformal-based technique. The median follow-up time was 8.5 years. Results: The 10-year PSA relapse-free survival outcome among patients with pre-radiation therapy PSA nadirs of ?0.3 ng/mL was 74.3%, compared with 57.7% for patients with higher PSA nadir values (P<.001). The 10-year distant metastases-free survival outcome among patients with pre-radiation therapy PSA nadirs of ?0.3 ng/mL was 86.1%, compared with 78.6% for patients with higher PSA nadir values (P=.004). In a competing-risk analysis, prostate cancer-related deaths were also significantly reduced among patients with pre-radiation therapy PSA nadirs of <0.3 ng/mL compared with higher values (7.8% compared with 13.7%; P=.009). Multivariable analysis demonstrated that the pre-EBRT PSA nadir value was a significant predictor of long-term biochemical tumor control, distant metastases-free survival, and cause-specific survival outcomes. Conclusions: Pre-radiation therapy nadir PSA values of ?0.3 ng/mL after neoadjuvant ADT were associated with improved long-term biochemical tumor control, reduction in distant metastases, and prostate cancer-related death. Patients with higher nadir values may require alternative adjuvant therapies to improve outcomes.

  12. Modern Radiation Therapy for Nodal Non-Hodgkin Lymphoma—Target Definition and Dose Guidelines From the International Lymphoma Radiation Oncology Group

    SciTech Connect (OSTI)

    Illidge, Tim; Specht, Lena; Yahalom, Joachim; Aleman, Berthe; Berthelsen, Anne Kiil; Constine, Louis; Dabaja, Bouthaina; Dharmarajan, Kavita; Ng, Andrea; Ricardi, Umberto; Wirth, Andrew

    2014-05-01

    Radiation therapy (RT) is the most effective single modality for local control of non-Hodgkin lymphoma (NHL) and is an important component of therapy for many patients. Many of the historic concepts of dose and volume have recently been challenged by the advent of modern imaging and RT planning tools. The International Lymphoma Radiation Oncology Group (ILROG) has developed these guidelines after multinational meetings and analysis of available evidence. The guidelines represent an agreed consensus view of the ILROG steering committee on the use of RT in NHL in the modern era. The roles of reduced volume and reduced doses are addressed, integrating modern imaging with 3-dimensional planning and advanced techniques of RT delivery. In the modern era, in which combined-modality treatment with systemic therapy is appropriate, the previously applied extended-field and involved-field RT techniques that targeted nodal regions have now been replaced by limiting the RT to smaller volumes based solely on detectable nodal involvement at presentation. A new concept, involved-site RT, defines the clinical target volume. For indolent NHL, often treated with RT alone, larger fields should be considered. Newer treatment techniques, including intensity modulated RT, breath holding, image guided RT, and 4-dimensional imaging, should be implemented, and their use is expected to decrease significantly the risk for normal tissue damage while still achieving the primary goal of local tumor control.

  13. Under-Sodium Viewing: A Review of Ultrasonic Imaging Technology for Liquid Metal Fast Reactors

    SciTech Connect (OSTI)

    Griffin, Jeffrey W.; Peters, Timothy J.; Posakony, Gerald J.; Chien, Hual-Te; Bond, Leonard J.; Denslow, Kayte M.; Sheen, Shuh-Haw; Raptis, Paul

    2009-03-27

    This current report is a summary of information obtained in the "Information Capture" task of the U.S. DOE-funded "Under Sodium Viewing (USV) Project." The goal of the multi-year USV project is to design, build, and demonstrate a state-of-the-art prototype ultrasonic viewing system tailored for periodic reactor core in-service monitoring and maintenance inspections. The study seeks to optimize system parameters, improve performance, and re-establish this key technology area which will be required to support any new U.S. liquid-metal cooled fast reactors.

  14. Experiments at Scale with In-Situ Visualization Using ParaView/Catalyst in RAGE

    SciTech Connect (OSTI)

    Kares, Robert John

    2014-10-31

    In this paper I describe some numerical experiments performed using the ParaView/Catalyst in-situ visualization infrastructure deployed in the Los Alamos RAGE radiation-hydrodynamics code to produce images from a running large scale 3D ICF simulation on the Cielo supercomputer at Los Alamos. The detailed procedures for the creation of the visualizations using ParaView/Catalyst are discussed and several images sequences from the ICF simulation problem produced with the in-situ method are presented. My impressions and conclusions concerning the use of the in-situ visualization method in RAGE are discussed.

  15. Particles from Comet 81P/Wild 2 Viewed by ALS Microscopes

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Particles from Comet 81P/Wild 2 Viewed by ALS Microscopes Particles from Comet 81P/Wild 2 Viewed by ALS Microscopes Print Wednesday, 30 May 2007 00:00 NASA's $200-million, seven-year-long Stardust mission returned to Earth thousands of tiny particles snagged from the coma of comet 81P/Wild 2. Four ALS beamlines and the researchers using them were among the hundreds of scientists and dozens of experimental techniques in facilities around the world that contributed to the preliminary examination

  16. Jefferson Lab scientist puts intriguing view on spin of the proton |

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Jefferson Lab scientist puts intriguing view on spin of the proton Jefferson Lab scientist puts intriguing view on spin of the proton April 17, 2007 Newport News, Va. - A new result from the HERMES experiment at The German Electron Synchrotron DESY indicates that the gluons which bind quarks into the proton show only slight polarization. The result will be presented by Elke-Caroline Aschenauer, a former HERMES spokesperson and current 12 GeV Upgrade Hall D Leader at the Department of

  17. Capella Corona Revisited: a Combined View from Textit XMM-Newton RGS,

    Office of Scientific and Technical Information (OSTI)

    Textit Chandra HETGS, and LETGS (Conference) | SciTech Connect Conference: Capella Corona Revisited: a Combined View from Textit XMM-Newton RGS, Textit Chandra HETGS, and LETGS Citation Details In-Document Search Title: Capella Corona Revisited: a Combined View from Textit XMM-Newton RGS, Textit Chandra HETGS, and LETGS We present a combined analysis of the X-ray emission of the Capella corona obtained with XMM-Newton RGS, Chandra HETGS, and LETGS. An improved atomic line database and a new

  18. Capella Corona Revisited: a Combined View from Textit XMM-Newton RGS,

    Office of Scientific and Technical Information (OSTI)

    Textit Chandra HETGS, and LETGS (Conference) | SciTech Connect Conference: Capella Corona Revisited: a Combined View from Textit XMM-Newton RGS, Textit Chandra HETGS, and LETGS Citation Details In-Document Search Title: Capella Corona Revisited: a Combined View from Textit XMM-Newton RGS, Textit Chandra HETGS, and LETGS × You are accessing a document from the Department of Energy's (DOE) SciTech Connect. This site is a product of DOE's Office of Scientific and Technical Information (OSTI)

  19. A space-based, high-resolution view of notable changes in urban NO x

    Office of Scientific and Technical Information (OSTI)

    pollution around the world (2005-2014) (Journal Article) | SciTech Connect A space-based, high-resolution view of notable changes in urban NO x pollution around the world (2005-2014) Citation Details In-Document Search Title: A space-based, high-resolution view of notable changes in urban NO x pollution around the world (2005-2014) Nitrogen oxides (NOx = NO + NO2) are produced during combustion processes and, thus may serve as a proxy for fossil fuel-based energy usage and coemitted

  20. Prairie View A&M University | Princeton Plasma Physics Lab

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Design Competition | Department of Energy Prairie View A&M Tops 2016 U.S. Department of Energy Race to Zero Student Design Competition Prairie View A&M Tops 2016 U.S. Department of Energy Race to Zero Student Design Competition April 22, 2016 - 3:00pm Addthis As part of the Obama Administration's commitment to helping families across the United States save money by saving energy, the U.S. Department of Energy announced winners of its third annual Race to Zero Student Design

  1. Factors influencing radiation therapy student clinical placement satisfaction

    SciTech Connect (OSTI)

    Bridge, Pete; Carmichael, Mary-Ann

    2014-02-15

    Introduction: Radiation therapy students at Queensland University of Technology (QUT) attend clinical placements at five different clinical departments with varying resources and support strategies. This study aimed to determine the relative availability and perceived importance of different factors affecting student support while on clinical placement. The purpose of the research was to inform development of future support mechanisms to enhance radiation therapy students’ experience on clinical placement. Methods: This study used anonymous Likert-style surveys to gather data from years 1 and 2 radiation therapy students from QUT and clinical educators from Queensland relating to availability and importance of support mechanisms during clinical placements in a semester. Results: The study findings demonstrated student satisfaction with clinical support and suggested that level of support on placement influenced student employment choices. Staff support was perceived as more important than physical resources; particularly access to a named mentor, a clinical educator and weekly formative feedback. Both students and educators highlighted the impact of time pressures. Conclusions: The support offered to radiation therapy students by clinical staff is more highly valued than physical resources or models of placement support. Protected time and acknowledgement of the importance of clinical education roles are both invaluable. Joint investment in mentor support by both universities and clinical departments is crucial for facilitation of effective clinical learning.

  2. Proceedings of the first international symposium on neutron capture therapy

    SciTech Connect (OSTI)

    Fairchild, R.G.; Brownell, G.L.

    1982-01-01

    This meeting was arranged jointly by MIT and BNL in order to illuminate progress in the synthesis and targeting of boron compounds and to evaluate and document progress in radiobiological and dosimetric aspects of neutron capture therapy. It is hoped that this meeting will facilitate transfer of information between groups working in these fields, and encourage synergistic collaboration.

  3. Predictors of Postoperative Complications After Trimodality Therapy for Esophageal Cancer

    SciTech Connect (OSTI)

    Wang, Jingya [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Wei, Caimiao [Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Tucker, Susan L. [Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Myles, Bevan; Palmer, Matthew [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Hofstetter, Wayne L.; Swisher, Stephen G. [Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Ajani, Jaffer A. [Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Cox, James D.; Komaki, Ritsuko; Liao, Zhongxing [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Lin, Steven H., E-mail: SHLin@mdanderson.org [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States)

    2013-08-01

    Purpose: While trimodality therapy for esophageal cancer has improved patient outcomes, surgical complication rates remain high. The goal of this study was to identify modifiable factors associated with postoperative complications after neoadjuvant chemoradiation. Methods and Materials: From 1998 to 2011, 444 patients were treated at our institution with surgical resection after chemoradiation. Postoperative (pulmonary, gastrointestinal [GI], cardiac, wound healing) complications were recorded up to 30 days postoperatively. Kruskal-Wallis tests and ?{sup 2} or Fisher exact tests were used to assess associations between continuous and categorical variables. Multivariate logistic regression tested the association between perioperative complications and patient or treatment factors that were significant on univariate analysis. Results: The most frequent postoperative complications after trimodality therapy were pulmonary (25%) and GI (23%). Lung capacity and the type of radiation modality used were independent predictors of pulmonary and GI complications. After adjusting for confounding factors, pulmonary and GI complications were increased in patients treated with 3-dimensional conformal radiation therapy (3D-CRT) versus intensity modulated radiation therapy (IMRT; odds ratio [OR], 2.018; 95% confidence interval [CI], 1.104-3.688; OR, 1.704; 95% CI, 1.03-2.82, respectively) and for patients treated with 3D-CRT versus proton beam therapy (PBT; OR, 3.154; 95% CI, 1.365-7.289; OR, 1.55; 95% CI, 0.78-3.08, respectively). Mean lung radiation dose (MLD) was strongly associated with pulmonary complications, and the differences in toxicities seen for the radiation modalities could be fully accounted for by the MLD delivered by each of the modalities. Conclusions: The radiation modality used can be a strong mitigating factor of postoperative complications after neoadjuvant chemoradiation.

  4. Optic for industrial endoscope/borescope with narrow field of view and low distortion

    DOE Patents [OSTI]

    Stone, Gary F.; Trebes, James E.

    2005-08-16

    An optic for the imaging optics on the distal end of a flexible fiberoptic endoscope or rigid borescope inspection tool. The image coverage is over a narrow (<20 degrees) field of view with very low optical distortion (<5% pin cushion or barrel distortion), compared to the typical <20% distortion. The optic will permit non-contact surface roughness measurements using optical techniques. This optic will permit simultaneous collection of selected image plane data, which data can then be subsequently optically processed. The image analysis will yield non-contact surface topology data for inspection where access to the surface does not permit a mechanical styles profilometer verification of surface topology. The optic allows a very broad spectral band or range of optical inspection. It is capable of spectroscopic imaging and fluorescence induced imaging when a scanning illumination source is used. The total viewing angle for this optic is 10 degrees for the full field of view of 10 degrees, compared to 40-70 degrees full angle field of view of the conventional gradient index or GRIN's lens systems.

  5. DOE Zero Energy Ready Home Case Study: Clifton View Homes, Coupeville, Washington

    SciTech Connect (OSTI)

    none,

    2013-09-01

    Ted Clifton, founder of Clifton View Homes, achieved an impressive Home Energy Rating System (HERS) score of 34 (without solar panels) on a two-story home completed in July 2011 that also earned him his first Challenge Home certification from the U.S. Department of Energy (DOE). This home also garnered a 2013 Housing Innovation Award in the "systems builder" category.

  6. Thiourea derivatives, methods of their preparation and their use in neutron capture therapy of malignant melanoma

    DOE Patents [OSTI]

    Gabel, D.

    1991-06-04

    The present invention pertains to boron containing thiouracil derivatives, their method of preparations, and their use in the therapy of malignant melanoma using boron neutron capture therapy. No Drawings

  7. Boron containing compounds and their preparation and use in neutron capture therapy

    DOE Patents [OSTI]

    Gabel, D.

    1992-09-01

    The present invention pertains to boron containing thiouracil derivatives, their method of preparations, and their use in the therapy of malignant melanoma using boron neutron capture therapy. No Drawings

  8. Chemoradiotherapeutic wrinkled mesoporous silica nanoparticles for use in cancer therapy

    SciTech Connect (OSTI)

    Munaweera, Imalka; Balkus, Kenneth J. Jr. E-mail: Anthony.DiPasqua@unthsc.edu; Koneru, Bhuvaneswari; Shi, Yi; Di Pasqua, Anthony J. E-mail: Anthony.DiPasqua@unthsc.edu

    2014-11-01

    Over the last decade, the development and application of nanotechnology in cancer detection, diagnosis, and therapy have been widely reported. Engineering of vehicles for the simultaneous delivery of chemo- and radiotherapeutics increases the effectiveness of the therapy and reduces the dosage of each individual drug required to produce an observable therapeutic response. We here developed a novel chemoradiotherapeutic 1,2-dioleoyl-sn-glycero-3-phosphocholine lipid coated/uncoated platinum drug loaded, holmium-containing, wrinkled mesoporous silica nanoparticle. The materials were characterized with TEM, FTIR, {sup 1}H NMR, energy dispersive x-ray, inductively coupled plasma-mass spectrometry, and zeta potential measurements. In vitro platinum drug release from both lipid coated and uncoated chemoradiotherapeutic wrinkled mesoporous silica are reported. Various kinetic models were used to analyze the release kinetics. The radioactivity of the chemoradiotherapeutic nanocarriers was measured after neutron-activation.

  9. Halogenated sulfidohydroboranes for nuclear medicine and boron neutron capture therapy

    DOE Patents [OSTI]

    Miura, Michiko; Slatkin, Daniel N.

    1997-03-18

    A method for performing boron neutron capture therapy for the treatment of tumors is disclosed. The method includes administering to a patient an iodinated sulfidohydroborane, a boron-10-containing compound. The site of the tumor is localized by visualizing the increased concentration of the iodine labelled compound at the tumor. The targeted tumor is then irradiated with a beam of neutrons having an energy distribution effective for neutron capture. Destruction of the tumor occurs due to high LET particle irradiation of the tissue secondary to the incident neutrons being captured by the boron-10 nuclei. Iodinated sulfidohydroboranes are disclosed which are especially suitable for the method of the invention. In a preferred embodiment, a compound having the formula Na.sub.4 B.sub.12 I.sub.11 SSB.sub.12 I.sub.11, or another pharmaceutically acceptable salt of the compound, may be administered to a cancer patient for boron neutron capture therapy.

  10. Halogenated sulfidohydroboranes for nuclear medicine and boron neutron capture therapy

    DOE Patents [OSTI]

    Miura, Michiko; Slatkin, Daniel N.

    1997-08-05

    A method for performing boron neutron capture therapy for the treatment of tumors is disclosed. The method includes administering to a patient an iodinated sulfidohydroborane, a boron-10-containing compound. The site of the tumor is localized. by visualizing the increased concentration of the iodine labelled compound at the tumor. The targeted tumor is then irradiated with a beam of neutrons having an energy distribution effective for neutron capture. Destruction of the tumor occurs due to high LET particle irradiation of the tissue secondary to the incident neutrons being captured by the boron-10 nuclei. Iodinated sulfidohydroboranes are disclosed which are especially suitable for the method of the invention. In a preferred embodiment, a compound having the formula Na.sub.4 B.sub.12 I.sub.11 SSB.sub.12 I.sub.11, or another pharmaceutically acceptable salt of the compound, may be administered to a cancer patient for boron neutron capture therapy.

  11. Halogenated sulfidohydroboranes for nuclear medicine and boron neutron capture therapy

    DOE Patents [OSTI]

    Miura, Michiko; Slatkin, Daniel N.

    1995-10-03

    A method for performing boron neutron capture therapy for the treatment of tumors is disclosed. The method includes administering to a patient an iodinated sulfidohydroborane, a boron-10-containing compound. The site of the tumor is localized by visualizing the increased concentration of the iodine labelled compound at the tumor. The targeted tumor is then irradiated with a beam of neutrons having an energy distribution effective for neutron capture. Destruction of the tumor occurs due to high LET particle irradiation of the tissue secondary to the incident neutrons being captured by the boron-10 nuclei. Iodinated sulfidohydroboranes are disclosed which are especially suitable for the method of the invention. In a preferred embodiment, a compound having the formula Na.sub.4 B.sub.12 I.sub.11 SSB.sub.12 I.sub.11, or another pharmaceutically acceptable salt of the compound, may be administered to a cancer patient for boron neutron capture therapy.

  12. Halogenated sulfidohydroboranes for nuclear medicine and boron neutron capture therapy

    DOE Patents [OSTI]

    Miura, M.; Slatkin, D.N.

    1997-03-18

    A method for performing boron neutron capture therapy for the treatment of tumors is disclosed. The method includes administering to a patient an iodinated sulfidohydroborane, a boron-10-containing compound. The site of the tumor is localized by visualizing the increased concentration of the iodine labelled compound at the tumor. The targeted tumor is then irradiated with a beam of neutrons having an energy distribution effective for neutron capture. Destruction of the tumor occurs due to high LET particle irradiation of the tissue secondary to the incident neutrons being captured by the boron-10 nuclei. Iodinated sulfidohydroboranes are disclosed which are especially suitable for the method of the invention. In a preferred embodiment, a compound having the formula Na{sub 4}B{sub 12}I{sub 11}SSB{sub 12}I{sub 11}, or another pharmaceutically acceptable salt of the compound, may be administered to a cancer patient for boron neutron capture therapy. 1 fig.

  13. Halogenated sulfidohydroboranes for nuclear medicine and boron neutron capture therapy

    DOE Patents [OSTI]

    Miura, M.; Slatkin, D.N.

    1997-08-05

    A method for performing boron neutron capture therapy for the treatment of tumors is disclosed. The method includes administering to a patient an iodinated sulfidohydroborane, a boron-10-containing compound. The site of the tumor is localized by visualizing the increased concentration of the iodine labelled compound at the tumor. The targeted tumor is then irradiated with a beam of neutrons having an energy distribution effective for neutron capture. Destruction of the tumor occurs due to high LET particle irradiation of the tissue secondary to the incident neutrons being captured by the boron-10 nuclei. Iodinated sulfidohydroboranes are disclosed which are especially suitable for the method of the invention. In a preferred embodiment, a compound having the formula Na{sub 4}B{sub 12}I{sub 11}SSB{sub 12}I{sub 11}, or another pharmaceutically acceptable salt of the compound, may be administered to a cancer patient for boron neutron capture therapy. 1 fig.

  14. Halogenated sulfidohydroboranes for nuclear medicine and boron neutron capture therapy

    DOE Patents [OSTI]

    Miura, M.; Slatkin, D.N.

    1995-10-03

    A method for performing boron neutron capture therapy for the treatment of tumors is disclosed. The method includes administering to a patient an iodinated sulfidohydroborane, a boron-10-containing compound. The site of the tumor is localized by visualizing the increased concentration of the iodine labelled compound at the tumor. The targeted tumor is then irradiated with a beam of neutrons having an energy distribution effective for neutron capture. Destruction of the tumor occurs due to high LET particle irradiation of the tissue secondary to the incident neutrons being captured by the boron-10 nuclei. Iodinated sulfidohydroboranes are disclosed which are especially suitable for the method of the invention. In a preferred embodiment, a compound having the formula Na{sub 4}B{sub 12}I{sub 11}SSB{sub 12}I{sub 11}, or another pharmaceutically acceptable salt of the compound, may be administered to a cancer patient for boron neutron capture therapy. 1 fig.

  15. Nanoscience and Nanotechnology: From Energy Applications to Advanced Medical Therapies

    ScienceCinema (OSTI)

    Tijana Rajh

    2010-01-08

    Dr. Rajh will present a general talk on nanotechnology ? an overview of why nanotechnology is important and how it is useful in various fields. The specific focus will be on Solar energy conversion, environmental applications and advanced medical therapies. She has broad expertise in synthesis and characterization of nanomaterials that are used in nanotechnology including novel hybrid systems connecting semiconductors to biological molecules like DNA and antibodies. This technology could lead to new gene therapy procedures, cancer treatments and other medical applications. She will also discuss technologies made possible by organizing small semiconductor particles called quantum dots, materials that exhibit a rich variety of phenomena that are size and shape dependent. Development of these new materials that harnesses the unique properties of materials at the 1-100 nanometer scale resulted in the new field of nanotechnology that currently affects many applications in technological and medical fields.

  16. Prototype demonstration of radiation therapy planning code system

    SciTech Connect (OSTI)

    Little, R.C.; Adams, K.J.; Estes, G.P.; Hughes, L.S. III; Waters, L.S.

    1996-09-01

    This is the final report of a one-year, Laboratory-Directed Research and Development project at the Los Alamos National Laboratory (LANL). Radiation therapy planning is the process by which a radiation oncologist plans a treatment protocol for a patient preparing to undergo radiation therapy. The objective is to develop a protocol that delivers sufficient radiation dose to the entire tumor volume, while minimizing dose to healthy tissue. Radiation therapy planning, as currently practiced in the field, suffers from inaccuracies made in modeling patient anatomy and radiation transport. This project investigated the ability to automatically model patient-specific, three-dimensional (3-D) geometries in advanced Los Alamos radiation transport codes (such as MCNP), and to efficiently generate accurate radiation dose profiles in these geometries via sophisticated physics modeling. Modem scientific visualization techniques were utilized. The long-term goal is that such a system could be used by a non-expert in a distributed computing environment to help plan the treatment protocol for any candidate radiation source. The improved accuracy offered by such a system promises increased efficacy and reduced costs for this important aspect of health care.

  17. March 2016 Most Viewed Documents for Biology And Medicine | OSTI, US Dept

    Office of Scientific and Technical Information (OSTI)

    of Energy, Office of Scientific and Technical Information March 2016 Most Viewed Documents for Biology And Medicine Measuring dopamine release in the human brain with PET Volkow, N.D. [Brookhaven National Lab., Upton, NY (United States)]|[State Univ. of New York at Stony Brook, Stony Brook, NY (United States). Dept. of Psychiatry]; Fowler, J.S.; Logan, J.; Wang, G.J. [Brookhaven National Lab., Upton, NY (United States)] (1995) 206 Drug Retention Times Center for Human Reliability Studies

  18. March 2016 Most Viewed Documents for Geosciences | OSTI, US Dept of Energy,

    Office of Scientific and Technical Information (OSTI)

    Office of Scientific and Technical Information March 2016 Most Viewed Documents for Geosciences Gas-phase diffusion in porous media: Evaluation of an advective- dispersive formulation and the dusty-gas model including comparison to data for binary mixtures Webb, S.W. (1996) 88 Evaluation of soil liquefaction potential for level ground during earthquakes. A summary report Seed, H.B.; Arango, I.; Chan, C.K. (1975) 71 Fundamental Research on Percussion Drilling: Improved rock mechanics

  19. March 2016 Most Viewed Documents for Renewable Energy Sources | OSTI, US

    Office of Scientific and Technical Information (OSTI)

    Dept of Energy, Office of Scientific and Technical Information March 2016 Most Viewed Documents for Renewable Energy Sources Wind energy applications guide anon. (2001) 557 Aerodynamic characteristics of seven symmetrical airfoil sections through 180-degree angle of attack for use in aerodynamic analysis of vertical axis wind turbines Sheldahl, R E; Klimas, P C (1981) 474 Calculation of brine properties. [Above 80/sup 0/F and for salt content between 5 and 25%] Dittman, G.L. (1977) 285

  20. April 2013 Most Viewed Documents for Biology And Medicine | OSTI, US Dept

    Office of Scientific and Technical Information (OSTI)

    of Energy, Office of Scientific and Technical Information April 2013 Most Viewed Documents for Biology And Medicine Science Subject Feed Publications in biomedical and environmental sciences programs, 1981 Moody, J.B. (comp.) (1982) 306 /> Drug Retention Times Center for Human Reliability Studies (2007) 99 /> SURVEY OF NOISE SUPPRESSION SYSTEMS FOR ENGINE GENERATOR SETS. KRISHNA,C.R. (1999) 95 /> Defining the Effectiveness of UV Lamps Installed in Circulating Air Ductwork Douglas

  1. April 2013 Most Viewed Documents for Environmental Sciences | OSTI, US Dept

    Office of Scientific and Technical Information (OSTI)

    of Energy, Office of Scientific and Technical Information April 2013 Most Viewed Documents for Environmental Sciences Science Subject Feed Building a secondary containment system Broder, M.F. (1994) 144 /> Methods and opportunities in the recycling of rare earth based materials Ellis, T.W.; Schmidt, F.A.; Jones, L.L. (1994) 134 /> Ecological Screening Values for Surface Water, Sediment, and Soil Friday, G. P. (1999) 128 /> Ammonia usage in vapor compression for refrigeration and

  2. April 2013 Most Viewed Documents for Geosciences | OSTI, US Dept of Energy,

    Office of Scientific and Technical Information (OSTI)

    Office of Scientific and Technical Information April 2013 Most Viewed Documents for Geosciences Sloshing analysis of viscous liquid storage tanks Uras, R.Z. (1995) 83 Seismic design evaluation guidelines for buried piping for the DOE HLW Facilities Lin, Chi-Wen [Consultant, Martinez, CA (United States)]; Antaki, G. [Westinghouse Savannah River Co., Aiken, SC (United States)]; Bandyopadhyay, K. [Brookhaven National Lab., Upton, NY (United States)]; Bush, S.H. [Review & Synthesis

  3. April 2013 Most Viewed Documents for Mathematics And Computing | OSTI, US

    Office of Scientific and Technical Information (OSTI)

    Dept of Energy, Office of Scientific and Technical Information April 2013 Most Viewed Documents for Mathematics And Computing Science Subject Feed Publications in biomedical and environmental sciences programs, 1981 Moody, J.B. (comp.) (1982) 306 /> A comparison of risk assessment techniques from qualitative to quantitative Altenbach, T.J. (1995) 159 /> Lecture notes for introduction to safety and health Biele, F. (1992) 138 /> Analytical considerations in the code qualification of

  4. April 2013 Most Viewed Documents for Physics | OSTI, US Dept of Energy,

    Office of Scientific and Technical Information (OSTI)

    Office of Scientific and Technical Information April 2013 Most Viewed Documents for Physics Science Subject Feed Lithium literature review: lithium's properties and interactions Jeppson, D.W.; Ballif, J.L.; Yuan, W.W.; Chou, B.E. (1978) 123 /> Plastic Gamma Sensors: An Application in Detection of Radioisotopes S. Mukhopadhyay (2003) 85 /> Organic light emitting diodes (OLEDS) and OLED-based structurally integrated optical sensors Cai, Yuankun (2010) 83 /> White LED with High Package

  5. April 2013 Most Viewed Documents for Renewable Energy Sources | OSTI, US

    Office of Scientific and Technical Information (OSTI)

    Dept of Energy, Office of Scientific and Technical Information April 2013 Most Viewed Documents for Renewable Energy Sources Science Subject Feed Chapter 11. Heat Exchangers Rafferty, Kevin D.; Culver, Gene (1998) 1252 /> Seventh Edition Fuel Cell Handbook NETL (2004) 628 /> Wet cooling towers: rule-of-thumb design and simulation Leeper, S.A. (1981) 290 /> Chapter 17. Engineering cost analysis Higbee, Charles V. (1998) 223 /> Geothermal Power Generation - A Primer on

  6. SCIENCE ON SATURDAY- "A Robot's View of Our Ocean Planet" | Princeton

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Plasma Physics Lab 16, 2013, 9:30am Science On Saturday MBG Auditorium SCIENCE ON SATURDAY- "A Robot's View of Our Ocean Planet" Professor Josh Kohut, Assistant Professor of Oceanography Center for Coastal Physical Oceanography, Rutgers University Presentation: PDF icon SOS16MAR2013_JKohut.pdf Science on Saturday is a series of lectures given by scientists, mathematicians, and other professionals involved in cutting-edge research. Held on Saturday mornings throughout winter, the

  7. Particles from Comet 81P/Wild 2 Viewed by ALS Microscopes

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Particles from Comet 81P/Wild 2 Viewed by ALS Microscopes Print NASA's $200-million, seven-year-long Stardust mission returned to Earth thousands of tiny particles snagged from the coma of comet 81P/Wild 2. Four ALS beamlines and the researchers using them were among the hundreds of scientists and dozens of experimental techniques in facilities around the world that contributed to the preliminary examination of the first samples. Adding to recent advances in cometary science showing the

  8. Particles from Comet 81P/Wild 2 Viewed by ALS Microscopes

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Particles from Comet 81P/Wild 2 Viewed by ALS Microscopes Print NASA's $200-million, seven-year-long Stardust mission returned to Earth thousands of tiny particles snagged from the coma of comet 81P/Wild 2. Four ALS beamlines and the researchers using them were among the hundreds of scientists and dozens of experimental techniques in facilities around the world that contributed to the preliminary examination of the first samples. Adding to recent advances in cometary science showing the

  9. Particles from Comet 81P/Wild 2 Viewed by ALS Microscopes

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Particles from Comet 81P/Wild 2 Viewed by ALS Microscopes Print NASA's $200-million, seven-year-long Stardust mission returned to Earth thousands of tiny particles snagged from the coma of comet 81P/Wild 2. Four ALS beamlines and the researchers using them were among the hundreds of scientists and dozens of experimental techniques in facilities around the world that contributed to the preliminary examination of the first samples. Adding to recent advances in cometary science showing the

  10. Particles from Comet 81P/Wild 2 Viewed by ALS Microscopes

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Particles from Comet 81P/Wild 2 Viewed by ALS Microscopes Print NASA's $200-million, seven-year-long Stardust mission returned to Earth thousands of tiny particles snagged from the coma of comet 81P/Wild 2. Four ALS beamlines and the researchers using them were among the hundreds of scientists and dozens of experimental techniques in facilities around the world that contributed to the preliminary examination of the first samples. Adding to recent advances in cometary science showing the

  11. Particles from Comet 81P/Wild 2 Viewed by ALS Microscopes

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Particles from Comet 81P/Wild 2 Viewed by ALS Microscopes Print NASA's $200-million, seven-year-long Stardust mission returned to Earth thousands of tiny particles snagged from the coma of comet 81P/Wild 2. Four ALS beamlines and the researchers using them were among the hundreds of scientists and dozens of experimental techniques in facilities around the world that contributed to the preliminary examination of the first samples. Adding to recent advances in cometary science showing the

  12. Particles from Comet 81P/Wild 2 Viewed by ALS Microscopes

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Particles from Comet 81P/Wild 2 Viewed by ALS Microscopes Print NASA's $200-million, seven-year-long Stardust mission returned to Earth thousands of tiny particles snagged from the coma of comet 81P/Wild 2. Four ALS beamlines and the researchers using them were among the hundreds of scientists and dozens of experimental techniques in facilities around the world that contributed to the preliminary examination of the first samples. Adding to recent advances in cometary science showing the

  13. Particles from Comet 81P/Wild 2 Viewed by ALS Microscopes

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Particles from Comet 81P/Wild 2 Viewed by ALS Microscopes Print NASA's $200-million, seven-year-long Stardust mission returned to Earth thousands of tiny particles snagged from the coma of comet 81P/Wild 2. Four ALS beamlines and the researchers using them were among the hundreds of scientists and dozens of experimental techniques in facilities around the world that contributed to the preliminary examination of the first samples. Adding to recent advances in cometary science showing the

  14. Residential Windows and Window Coverings: A Detailed View of the Installed Base and User Behavior

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Residential Windows and Window Coverings: A Detailed View of the Installed Base and User Behavior SEPTEMBER 2013 Prepared for: Building Technologies Office Office of Energy Efficiency and Renewable Energy U.S. Department of Energy Prepared by: D&R International, Ltd. September 2013 Prepared for: Building Technologies Office Office of Energy Efficiency and Renewable Energy U.S. Department of Energy Prepared By: D&R International, Ltd. 1300 Spring Street, Suite 500 Silver Spring, MD 20910

  15. 3D View Inside the Skeleton with X-ray Microscopy: Imaging Bone at the

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Nanoscale 3D View Inside the Skeleton with X-ray Microscopy: Imaging Bone at the Nanoscale Scientists studying osteoporosis and other skeletal diseases are interested in the 3D structure of bone and its responses to conditions such as weightlessness, radiation (of particular interest to astronauts) and vitamin D deficiency. The current gold standard, micro-computed tomography (micro-CT), provides 3D images of trabeculae, the small interior struts of bone tissue, and electron microscopy can

  16. September 2013 Most Viewed Documents for Biology And Medicine | OSTI, US

    Office of Scientific and Technical Information (OSTI)

    Dept of Energy, Office of Scientific and Technical Information September 2013 Most Viewed Documents for Biology And Medicine Science Subject Feed Drug Retention Times Center for Human Reliability Studies (2007) 29 /> Oleoresin Capsicum toxicology evaluation and hazard review Archuleta, M.M. (1995) 27 /> SURVEY OF NOISE SUPPRESSION SYSTEMS FOR ENGINE GENERATOR SETS. KRISHNA,C.R. (1999) 27 /> Site-Directed Research and Development FY 2012 Annual Report , (2013) 27 /> Human

  17. September 2015 Most Viewed Documents for Biology And Medicine | OSTI, US

    Office of Scientific and Technical Information (OSTI)

    Dept of Energy, Office of Scientific and Technical Information September 2015 Most Viewed Documents for Biology And Medicine Measuring dopamine release in the human brain with PET Volkow, N.D. [Brookhaven National Lab., Upton, NY (United States)]|[State Univ. of New York at Stony Brook, Stony Brook, NY (United States). Dept. of Psychiatry]; Fowler, J.S.; Logan, J.; Wang, G.J. [Brookhaven National Lab., Upton, NY (United States)] (1995) 168 Drug Retention Times Center for Human Reliability

  18. January 2013 Most Viewed Documents for Biology And Medicine | OSTI, US Dept

    Office of Scientific and Technical Information (OSTI)

    of Energy, Office of Scientific and Technical Information January 2013 Most Viewed Documents for Biology And Medicine Nevada Test Site Radiological Control Manual Radiological Control Managers' Council Nevada Test Site Effects of ionizing radiation on the boreal forest: Canada's FIG experiment, with implications for radionuclides Amiro, B.D.; Sheppard, S.C Assessment of atmospheric metallic pollution in the metropolitan region of Sao Paulo, Brazil, employing Tillandsia usneoides L. as

  19. January 2013 Most Viewed Documents for Materials | OSTI, US Dept of Energy,

    Office of Scientific and Technical Information (OSTI)

    Office of Scientific and Technical Information January 2013 Most Viewed Documents for Materials Evaluation of the inhibitive effect of some plant extracts on the acid corrosion of mild steel Oguzie, Emeka E. [Electrochemistry and Materials Science Research Laboratory, Department of Chemistry, Federal University of Technology, PMB 1526, Owerri (Nigeria)], E-mail: oguziemeka@yahoo.com Superconducting wind turbine generators Abrahamsen, A B; Seiler, E; Zirngibl, T; Andersen, N H [Materials

  20. January 2013 Most Viewed Documents for Mathematics And Computing | OSTI, US

    Office of Scientific and Technical Information (OSTI)

    Dept of Energy, Office of Scientific and Technical Information January 2013 Most Viewed Documents for Mathematics And Computing Cybersecurity through Real-Time Distributed Control Systems Kisner, Roger A [ORNL]; Manges, Wayne W [ORNL]; MacIntyre, Lawrence Paul [ORNL]; Nutaro, James J [ORNL]; Munro Jr, John K [ORNL]; Ewing, Paul D [ORNL]; Howlader, Mostofa [ORNL]; Kuruganti, Phani Teja [ORNL]; Wallace, Richard M [ORNL]; Olama, Mohammed M [ORNL] REACTOR ANALYSIS AND VIRTUAL CONTROL ENVIRONMENT

  1. January 2013 Most Viewed Documents for Renewable Energy Sources | OSTI, US

    Office of Scientific and Technical Information (OSTI)

    Dept of Energy, Office of Scientific and Technical Information January 2013 Most Viewed Documents for Renewable Energy Sources Photovoltaic Materials Duty, C.; Angelini, J.; Armstrong, B.; Bennett, C.; Evans, B.; Jellison, G. E.; Joshi, P.; List, F.; Paranthaman, P.; Parish, C.; Wereszczak, A. High Efficiency CdTe and CIGS Thin Film Solar Cells: Highlights of the Technologies Challenges (Presentation) Noufi, R. Accelerated UV Test Methods for Encapsulants of Photovoltaic Modules

  2. July 2013 Most Viewed Documents for Biology And Medicine | OSTI, US Dept of

    Office of Scientific and Technical Information (OSTI)

    Energy, Office of Scientific and Technical Information July 2013 Most Viewed Documents for Biology And Medicine Science Subject Feed Carbon Dioxide Sequestering Using Microalgal Systems Daniel J. Stepan; Richard E. Shockey; Thomas A. Moe; Ryan Dorn (2002) 51 /> SURVEY OF NOISE SUPPRESSION SYSTEMS FOR ENGINE GENERATOR SETS. KRISHNA,C.R. (1999) 46 /> Human radiation studies: Remembering the early years. Oral history of Donner Lab Administrator Baird G. Whaley, August 15, 1994 NONE (1995)

  3. July 2013 Most Viewed Documents for Engineering | OSTI, US Dept of Energy,

    Office of Scientific and Technical Information (OSTI)

    Office of Scientific and Technical Information July 2013 Most Viewed Documents for Engineering Science Subject Feed Heat Treatment Procedure Qualification -- Final Technical Report Robert C. Voigt (2004) 513 /> Charpy impact test results on five materials and NIST verification specimens using instrumented 2-mm and 8-mm strikers Nanstad, R.K.; Sokolov, M.A. (1995) 241 /> Conduction heat transfer solutions VanSant, J.H. (1980) 194 /> Damage identification and health monitoring of

  4. July 2013 Most Viewed Documents for Environmental Sciences | OSTI, US Dept

    Office of Scientific and Technical Information (OSTI)

    of Energy, Office of Scientific and Technical Information July 2013 Most Viewed Documents for Environmental Sciences Science Subject Feed Building a secondary containment system Broder, M.F. (1994) 98 /> Separation of heavy metals: Removal from industrial wastewaters and contaminated soil Peters, R.W.; Shem, L. (1993) 76 /> Ammonia usage in vapor compression for refrigeration and air-conditioning in the United States Fairchild, P.D.; Baxter, V.D. (1995) 58 /> Mitigation options for

  5. July 2013 Most Viewed Documents for Mathematics And Computing | OSTI, US

    Office of Scientific and Technical Information (OSTI)

    Dept of Energy, Office of Scientific and Technical Information July 2013 Most Viewed Documents for Mathematics And Computing Science Subject Feed Process Equipment Cost Estimation, Final Report H.P. Loh; Jennifer Lyons; Charles W. White, III (2002) 567 /> A comparison of risk assessment techniques from qualitative to quantitative Altenbach, T.J. (1995) 89 /> Lecture notes for introduction to safety and health Biele, F. (1992) 78 /> Computational procedures for determining parameters

  6. July 2013 Most Viewed Documents for Renewable Energy Sources | OSTI, US

    Office of Scientific and Technical Information (OSTI)

    Dept of Energy, Office of Scientific and Technical Information July 2013 Most Viewed Documents for Renewable Energy Sources Science Subject Feed Chapter 11. Heat Exchangers Rafferty, Kevin D.; Culver, Gene (1998) 484 /> Environmental Impacts of Wind Power Development on the Population Biology of Greater Prairie-Chickens Sandercock, Brett K. [Kansas State University] (2013) 184 /> Wet cooling towers: rule-of-thumb design and simulation Leeper, S.A. (1981) 154 /> A study of lead-acid

  7. June 2014 Most Viewed Documents for Biology And Medicine | OSTI, US Dept of

    Office of Scientific and Technical Information (OSTI)

    Energy, Office of Scientific and Technical Information June 2014 Most Viewed Documents for Biology And Medicine Science Subject Feed Modification to the Monte Carlo N-Particle (MCNP) Visual Editor (MCNPVised) to Read in Computer Aided Design (CAD) Files Randolph Schwarz; Leland L. Carter; Alysia Schwarz (2005) 37 /> Geothermal demonstration: Zunil food dehydration facility Maldonado, O. (Consultecnia, Guatemala City (Guatemala)); Altseimer, J.; Thayer, G.R. (Los Alamos National Lab., NM

  8. June 2014 Most Viewed Documents for Environmental Sciences | OSTI, US Dept

    Office of Scientific and Technical Information (OSTI)

    of Energy, Office of Scientific and Technical Information June 2014 Most Viewed Documents for Environmental Sciences Science Subject Feed Proceedings of the fifth annual NEA-seabed working group meeting Anderson, D. R. [ed.] (1980) 63 /> Separation of heavy metals: Removal from industrial wastewaters and contaminated soil Peters, R.W.; Shem, L. (1993) 50 /> Statistical methods for environmental pollution monitoring Gilbert, R.O. (1987) 42 /> Land use and energy Robeck, K.E.; Ballou,

  9. June 2014 Most Viewed Documents for Mathematics And Computing | OSTI, US

    Office of Scientific and Technical Information (OSTI)

    Dept of Energy, Office of Scientific and Technical Information June 2014 Most Viewed Documents for Mathematics And Computing Science Subject Feed Process Equipment Cost Estimation, Final Report H.P. Loh; Jennifer Lyons; Charles W. White, III (2002) 337 /> The Effects of Nuclear Weapons Glasstone, Samuel (1964) 71 /> Levenberg--Marquardt algorithm: implementation and theory More, J.J. (1977) 68 /> Computational procedures for determining parameters in Ramberg-Osgood elastoplastic

  10. June 2014 Most Viewed Documents for National Defense | OSTI, US Dept of

    Office of Scientific and Technical Information (OSTI)

    Energy, Office of Scientific and Technical Information June 2014 Most Viewed Documents for National Defense Science Subject Feed The Effects of Nuclear Weapons Glasstone, Samuel (1964) 71 /> Penetration equations Young, C.W. [Applied Research Associates, Inc., Albuquerque, NM (United States)] (1997) 29 /> Manual for the prediction of blast and fragment loadings on structures Not Available (1980) 29 /> Specific heat and thermal conductivity of explosives, mixtures, and plastic-bonded

  11. June 2014 Most Viewed Documents for Renewable Energy Sources | OSTI, US

    Office of Scientific and Technical Information (OSTI)

    Dept of Energy, Office of Scientific and Technical Information June 2014 Most Viewed Documents for Renewable Energy Sources Science Subject Feed Chapter 6. Drilling and Well Construction Culver, Gene (1998) 426 /> Chapter 11. Heat Exchangers Rafferty, Kevin D.; Culver, Gene (1998) 300 /> Seventh Edition Fuel Cell Handbook NETL (2004) 118 /> Chapter 17. Engineering cost analysis Higbee, Charles V. (1998) 115 /> Generalized displacement correlation method for estimating stress

  12. June 2015 Most Viewed Documents for Environmental Sciences | OSTI, US Dept

    Office of Scientific and Technical Information (OSTI)

    of Energy, Office of Scientific and Technical Information June 2015 Most Viewed Documents for Environmental Sciences Separation of heavy metals: Removal from industrial wastewaters and contaminated soil Peters, R.W.; Shem, L. (1993) 234 Statistical methods for environmental pollution monitoring Gilbert, R.O. (1987) 102 Building a secondary containment system Broder, M.F. (1994) 97 Mitigation options for accidental releases of hazardous gases Fthenakis, V.M. (1995) 87 Ammonia usage in vapor

  13. June 2015 Most Viewed Documents for Mathematics And Computing | OSTI, US

    Office of Scientific and Technical Information (OSTI)

    Dept of Energy, Office of Scientific and Technical Information June 2015 Most Viewed Documents for Mathematics And Computing Process Equipment Cost Estimation, Final Report H.P. Loh; Jennifer Lyons; Charles W. White, III (2002) 833 Lecture notes for introduction to safety and health Biele, F. (1992) 256 Systems engineering management plans. Rodriguez, Tamara S. (2009) 218 A comparison of risk assessment techniques from qualitative to quantitative Altenbach, T.J. (1995) 216 Ferrite

  14. March 2014 Most Viewed Documents for Environmental Sciences | OSTI, US Dept

    Office of Scientific and Technical Information (OSTI)

    of Energy, Office of Scientific and Technical Information 4 Most Viewed Documents for Environmental Sciences Science Subject Feed Separation of heavy metals: Removal from industrial wastewaters and contaminated soil Peters, R.W.; Shem, L. (1993) 57 /> Atmospheric Chemistry and Greenhouse Gases Ehhalt, D.; Prather, M.; Dentener, F.; Derwent, R.; Dlugokencky, Edward J.; Holland, E.; Isaksen, I.; Katima, J.; Kirchhoff, V.; Matson, P.; Midgley, P.; Wang, M.; Berntsen, T.; Bey, I.; Brasseur,

  15. March 2014 Most Viewed Documents for Mathematics And Computing | OSTI, US

    Office of Scientific and Technical Information (OSTI)

    Dept of Energy, Office of Scientific and Technical Information 4 Most Viewed Documents for Mathematics And Computing Science Subject Feed Process Equipment Cost Estimation, Final Report H.P. Loh; Jennifer Lyons; Charles W. White, III (2002) 291 /> Ten Problems in Experimental Mathematics Bailey, David H.; Borwein, Jonathan M.; Kapoor, Vishaal;Weisstein, Eric (2004) 101 /> The Effects of Nuclear Weapons Glasstone, Samuel (1964) 72 /> Levenberg--Marquardt algorithm: implementation and

  16. March 2014 Most Viewed Documents for Renewable Energy Sources | OSTI, US

    Office of Scientific and Technical Information (OSTI)

    Dept of Energy, Office of Scientific and Technical Information 4 Most Viewed Documents for Renewable Energy Sources Science Subject Feed Chapter 6. Drilling and Well Construction Culver, Gene (1998) 299 /> Chapter 11. Heat Exchangers Rafferty, Kevin D.; Culver, Gene (1998) 184 /> Chapter 17. Engineering cost analysis Higbee, Charles V. (1998) 124 /> Solar radiation data manual for flat-plate and concentrating collectors Dunlap, M.A. [ed.]; Marion, W.; Wilcox, S. (null) 74 />

  17. March 2015 Most Viewed Documents for Engineering | OSTI, US Dept of Energy,

    Office of Scientific and Technical Information (OSTI)

    Office of Scientific and Technical Information 5 Most Viewed Documents for Engineering Heat Treatment Procedure Qualification -- Final Technical Report Robert C. Voigt (2004) 325 Stress analysis and evaluation of a rectangular pressure vessel. [For equipment for sampling Hanford tank radwaste] Rezvani, M.A.; Ziada, H.H. (Westinghouse Hanford Co., Richland, WA (United States)); Shurrab, M.S. (Westinghouse Savannah River Co., Aiken, SC (United States)) (1992) 223 Conduction heat transfer

  18. March 2015 Most Viewed Documents for Environmental Sciences | OSTI, US Dept

    Office of Scientific and Technical Information (OSTI)

    of Energy, Office of Scientific and Technical Information 5 Most Viewed Documents for Environmental Sciences Separation of heavy metals: Removal from industrial wastewaters and contaminated soil Peters, R.W.; Shem, L. (1993) 229 Statistical methods for environmental pollution monitoring Gilbert, R.O. (1987) 131 Health and environmental effects document on geothermal energy: 1981 Layton, D.W.; Anspaugh, L.R.; O'Banion, K.D. (1981) 95 Study of using oxygen-enriched combustion air for

  19. March 2015 Most Viewed Documents for Mathematics And Computing | OSTI, US

    Office of Scientific and Technical Information (OSTI)

    Dept of Energy, Office of Scientific and Technical Information 5 Most Viewed Documents for Mathematics And Computing Process Equipment Cost Estimation, Final Report H.P. Loh; Jennifer Lyons; Charles W. White, III (2002) 1019 A comparison of risk assessment techniques from qualitative to quantitative Altenbach, T.J. (1995) 183 Lecture notes for introduction to safety and health Biele, F. (1992) 172 Mort User's Manual: For use with the Management Oversight and Risk Tree analytical logic

  20. March 2015 Most Viewed Documents for Renewable Energy Sources | OSTI, US

    Office of Scientific and Technical Information (OSTI)

    Dept of Energy, Office of Scientific and Technical Information 5 Most Viewed Documents for Renewable Energy Sources Chapter 11. Heat Exchangers Rafferty, Kevin D.; Culver, Gene (1998) 386 Wet cooling towers: rule-of-thumb design and simulation Leeper, S.A. (1981) 234 Aerodynamic characteristics of seven symmetrical airfoil sections through 180-degree angle of attack for use in aerodynamic analysis of vertical axis wind turbines Sheldahl, R E; Klimas, P C (1981) 159 Calculation of brine

  1. Most Viewed Documents for National Defense: December 2014 | OSTI, US Dept

    Office of Scientific and Technical Information (OSTI)

    of Energy, Office of Scientific and Technical Information Most Viewed Documents for National Defense: December 2014 A survey of combustible metals, thermites, and intermetallics for pyrotechnic applications Fischer, S.H.; Grubelich, M.C. (1996) 53 Precision linear shaped charge analyses for severance of metals Vigil, M.G. (1996) 36 Comments on TNT Equivalence Cooper, P.W. (1994) 32 Specific heat and thermal conductivity of explosives, mixtures, and plastic-bonded explosives determined

  2. December 2015 Most Viewed Documents for Biology And Medicine | OSTI, US

    Office of Scientific and Technical Information (OSTI)

    Dept of Energy, Office of Scientific and Technical Information December 2015 Most Viewed Documents for Biology And Medicine Measuring dopamine release in the human brain with PET Volkow, N.D. [Brookhaven National Lab., Upton, NY (United States)]|[State Univ. of New York at Stony Brook, Stony Brook, NY (United States). Dept. of Psychiatry]; Fowler, J.S.; Logan, J.; Wang, G.J. [Brookhaven National Lab., Upton, NY (United States)] (1995) 160 Drug Retention Times Center for Human Reliability

  3. December 2015 Most Viewed Documents for Renewable Energy Sources | OSTI, US

    Office of Scientific and Technical Information (OSTI)

    Dept of Energy, Office of Scientific and Technical Information December 2015 Most Viewed Documents for Renewable Energy Sources Aerodynamic characteristics of seven symmetrical airfoil sections through 180-degree angle of attack for use in aerodynamic analysis of vertical axis wind turbines Sheldahl, R E; Klimas, P C (1981) 307 Calculation of brine properties. [Above 80/sup 0/F and for salt content between 5 and 25%] Dittman, G.L. (1977) 228 Temperature coefficients for PV modules and

  4. Going Back to Californium: A Changing View of Covalency | U.S. DOE Office

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of Science (SC) Going Back to Californium: A Changing View of Covalency Basic Energy Sciences (BES) BES Home About Research Facilities Science Highlights Benefits of BES Funding Opportunities Basic Energy Sciences Advisory Committee (BESAC) Community Resources Contact Information Basic Energy Sciences U.S. Department of Energy SC-22/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3081 F: (301) 903-6594 E: Email Us More Information » 05.01.15 Going Back to

  5. A Network-based View of the U.S. Energy Sector

    U.S. Energy Information Administration (EIA) Indexed Site

    A Network-based View of the U.S. Energy Sector Vipin Arora | Elizabeth Sendich | Julia Teng February 2016 Independent Statistics & Analysis www.eia.gov U.S. Energy Information Administration Washington, DC 20585 This paper is released to encourage discussion and critical comment. The analysis and conclusions expressed here are those of the authors and not necessarily those of the U.S. Energy Information Administration. WORKING PAPER SERIES February 2016 Vipin Arora, Elizabeth Sendich, and

  6. Implementation of Remote 3-Dimensional Image Guided Radiation Therapy Quality Assurance for Radiation Therapy Oncology Group Clinical Trials

    SciTech Connect (OSTI)

    Cui Yunfeng; Galvin, James M.; Radiation Therapy Oncology Group, American College of Radiology, Philadelphia, Pennsylvania ; Parker, William; Breen, Stephen; Yin Fangfang; Cai Jing; Papiez, Lech S.; Li, X. Allen; Bednarz, Greg; Chen Wenzhou; Xiao Ying

    2013-01-01

    Purpose: To report the process and initial experience of remote credentialing of three-dimensional (3D) image guided radiation therapy (IGRT) as part of the quality assurance (QA) of submitted data for Radiation Therapy Oncology Group (RTOG) clinical trials; and to identify major issues resulting from this process and analyze the review results on patient positioning shifts. Methods and Materials: Image guided radiation therapy datasets including in-room positioning CT scans and daily shifts applied were submitted through the Image Guided Therapy QA Center from institutions for the IGRT credentialing process, as required by various RTOG trials. A centralized virtual environment is established at the RTOG Core Laboratory, containing analysis tools and database infrastructure for remote review by the Physics Principal Investigators of each protocol. The appropriateness of IGRT technique and volumetric image registration accuracy were evaluated. Registration accuracy was verified by repeat registration with a third-party registration software system. With the accumulated review results, registration differences between those obtained by the Physics Principal Investigators and from the institutions were analyzed for different imaging sites, shift directions, and imaging modalities. Results: The remote review process was successfully carried out for 87 3D cases (out of 137 total cases, including 2-dimensional and 3D) during 2010. Frequent errors in submitted IGRT data and challenges in the review of image registration for some special cases were identified. Workarounds for these issues were developed. The average differences of registration results between reviewers and institutions ranged between 2 mm and 3 mm. Large discrepancies in the superior-inferior direction were found for megavoltage CT cases, owing to low spatial resolution in this direction for most megavoltage CT cases. Conclusion: This first experience indicated that remote review for 3D IGRT as part of QA for RTOG clinical trials is feasible and effective. The magnitude of registration discrepancy between institution and reviewer was presented, and the major issues were investigated to further improve this remote evaluation process.

  7. Fast optimization and dose calculation in scanned ion beam therapy

    SciTech Connect (OSTI)

    Hild, S.; Graeff, C.; Trautmann, J.; Kraemer, M.; Zink, K.; Durante, M.; Bert, C.

    2014-07-15

    Purpose: Particle therapy (PT) has advantages over photon irradiation on static tumors. An increased biological effectiveness and active target conformal dose shaping are strong arguments for PT. However, the sensitivity to changes of internal geometry complicates the use of PT for moving organs. In case of interfractionally moving objects adaptive radiotherapy (ART) concepts known from intensity modulated radiotherapy (IMRT) can be adopted for PT treatments. One ART strategy is to optimize a new treatment plan based on daily image data directly before a radiation fraction is delivered [treatment replanning (TRP)]. Optimizing treatment plans for PT using a scanned beam is a time consuming problem especially for particles other than protons where the biological effective dose has to be calculated. For the purpose of TRP, fast optimization and fast dose calculation have been implemented into the GSI in-house treatment planning system (TPS) TRiP98. Methods: This work reports about the outcome of a code analysis that resulted in optimization of the calculation processes as well as implementation of routines supporting parallel execution of the code. To benchmark the new features, the calculation time for therapy treatment planning has been studied. Results: Compared to the original version of the TPS, calculation times for treatment planning (optimization and dose calculation) have been improved by a factor of 10 with code optimization. The parallelization of the TPS resulted in a speedup factor of 12 and 5.5 for the original version and the code optimized version, respectively. Hence the total speedup of the new implementation of the authors' TPS yielded speedup factors up to 55. Conclusions: The improved TPS is capable of completing treatment planning for ion beam therapy of a prostate irradiation considering organs at risk in this has been overseen in the review process. Also see below 6 min.

  8. Clinical Implementation of Intensity Modulated Proton Therapy for Thoracic Malignancies

    SciTech Connect (OSTI)

    Chang, Joe Y.; Li, Heng; Zhu, X. Ronald; Liao, Zhongxing; Zhao, Lina; Liu, Amy; Li, Yupeng; Sahoo, Narayan; Poenisch, Falk; Gomez, Daniel R.; Wu, Richard; Gillin, Michael; Zhang, Xiaodong

    2014-11-15

    Purpose: Intensity modulated proton therapy (IMPT) can improve dose conformality and better spare normal tissue over passive scattering techniques, but range uncertainties complicate its use, particularly for moving targets. We report our early experience with IMPT for thoracic malignancies in terms of motion analysis and management, plan optimization and robustness, and quality assurance. Methods and Materials: Thirty-four consecutive patients with lung/mediastinal cancers received IMPT to a median 66 Gy(relative biological equivalence [RBE]). All patients were able to undergo definitive radiation therapy. IMPT was used when the treating physician judged that IMPT conferred a dosimetric advantage; all patients had minimal tumor motion (<5 mm) and underwent individualized tumor-motion dose-uncertainty analysis and 4-dimensional (4D) computed tomographic (CT)-based treatment simulation and motion analysis. Plan robustness was optimized by using a worst-case scenario method. All patients had 4D CT repeated simulation during treatment. Results: IMPT produced lower mean lung dose (MLD), lung V{sub 5} and V{sub 20}, heart V{sub 40}, and esophageal V{sub 60} than did IMRT (P<.05) and lower MLD, lung V{sub 20}, and esophageal V{sub 60} than did passive scattering proton therapy (PSPT) (P<.05). D{sub 5} to the gross tumor volume and clinical target volume was higher with IMPT than with intensity modulated radiation therapy or PSPT (P<.05). All cases were analyzed for beam-angle-specific motion, water-equivalent thickness, and robustness. Beam angles were chosen to minimize the effect of respiratory motion and avoid previously treated regions, and the maximum deviation from the nominal dose-volume histogram values was kept at <5% for the target dose and met the normal tissue constraints under a worst-case scenario. Patient-specific quality assurance measurements showed that a median 99% (range, 95% to 100%) of the pixels met the 3% dose/3 mm distance criteria for the γ index. Adaptive replanning was used for 9 patients (26.5%). Conclusions: IMPT using 4D CT-based planning, motion management, and optimization was implemented successfully and met our quality assurance parameters for treating challenging thoracic cancers.

  9. Few-view cone-beam CT reconstruction with deformed prior image

    SciTech Connect (OSTI)

    Zhang, Hua; Ouyang, Luo; Wang, Jing E-mail: jing.wang@utsouthwestern.edu; Huang, Jing; Ma, Jianhua E-mail: jing.wang@utsouthwestern.edu; Chen, Wufan

    2014-12-15

    Purpose: Prior images can be incorporated into the image reconstruction process to improve the quality of subsequent cone-beam CT (CBCT) images from sparse-view or low-dose projections. The purpose of this work is to develop a deformed prior image-based reconstruction (DPIR) strategy to mitigate the deformation between the prior image and the target image. Methods: The deformed prior image is obtained by a projection-based registration approach. Specifically, the deformation vector fields used to deform the prior image are estimated through iteratively matching the forward projection of the deformed prior image and the measured on-treatment projections. The deformed prior image is then used as the prior image in the standard prior image constrained compressed sensing (PICCS) algorithm. A simulation study on an XCAT phantom and a clinical study on a head-and-neck cancer patient were conducted to evaluate the performance of the proposed DPIR strategy. Results: The deformed prior image matches the geometry of the on-treatment CBCT more closely as compared to the original prior image. Consequently, the performance of the DPIR strategy from few-view projections is improved in comparison to the standard PICCS algorithm, based on both visual inspection and quantitative measures. In the XCAT phantom study using 20 projections, the average root mean squared error is reduced from 14% in PICCS to 10% in DPIR, and the average universal quality index increases from 0.88 in PICCS to 0.92 in DPIR. Conclusions: The present DPIR approach provides a practical solution to the mismatch problem between the prior image and target image, which improves the performance of the original PICCS algorithm for CBCT reconstruction from few-view or low-dose projections.

  10. March 2016 Most Viewed Documents for Chemistry | OSTI, US Dept of Energy,

    Office of Scientific and Technical Information (OSTI)

    Office of Scientific and Technical Information March 2016 Most Viewed Documents for Chemistry LITERATURE REVIEW OF BORIC ACID SOLUBILITY DATA Crapse, K.; Kyser, E. (2011) 342 Electrical conductivity measurements of aqueous electrolyte solutions at high temperatures and high pressures Ho, P.C.; Palmer, D.A. (1995) 331 Decomposition of calcium sulfate: a review of the literature. [62 refs] Swift, W M; Panek, A F; Smith, G W; Vogel, G J; Jonke, A A (1976) 175 Vapor-liquid equilibria for nitric

  11. March 2016 Most Viewed Documents for National Defense | OSTI, US Dept of

    Office of Scientific and Technical Information (OSTI)

    Energy, Office of Scientific and Technical Information March 2016 Most Viewed Documents for National Defense SMART BRIDGE: A tool for estimating the military load classification of bridges using varying levels of information Van Groningen, C.N.; Paddock, R.A. (1997) 201 Vapor-liquid equilibria for nitric acid-water and plutonium nitrate-nitric acid-water solutions Maimoni, A. (1980) 143 Comments on TNT Equivalence Cooper, P.W. (1994) 135 LLNL small-scale drop-hammer impact sensitivity test

  12. April 2013 Most Viewed Documents for Chemistry | OSTI, US Dept of Energy,

    Office of Scientific and Technical Information (OSTI)

    Office of Scientific and Technical Information April 2013 Most Viewed Documents for Chemistry Science Subject Feed Lithium literature review: lithium's properties and interactions Jeppson, D.W.; Ballif, J.L.; Yuan, W.W.; Chou, B.E. (1978) 123 /> Electrical conductivity measurements of aqueous electrolyte solutions at high temperatures and high pressures Ho, P.C.; Palmer, D.A. (1995) 102 /> Vapor-liquid equilibria for nitric acid-water and plutonium nitrate-nitric acid-water solutions

  13. April 2013 Most Viewed Documents for Materials | OSTI, US Dept of Energy,

    Office of Scientific and Technical Information (OSTI)

    Office of Scientific and Technical Information April 2013 Most Viewed Documents for Materials Science Subject Feed Fatigue design curves for 6061-T6 aluminum Yahr, G.T. (1993) 554 /> Charpy impact test results on five materials and NIST verification specimens using instrumented 2-mm and 8-mm strikers Nanstad, R.K.; Sokolov, M.A. (1995) 534 /> Heat Treatment Procedure Qualification -- Final Technical Report Robert C. Voigt (2004) 488 /> The influence of grain size on the mechanical

  14. April 2013 Most Viewed Documents for National Defense | OSTI, US Dept of

    Office of Scientific and Technical Information (OSTI)

    Energy, Office of Scientific and Technical Information April 2013 Most Viewed Documents for National Defense Science Subject Feed Vapor-liquid equilibria for nitric acid-water and plutonium nitrate-nitric acid-water solutions Maimoni, A. (1980) 95 /> SMART BRIDGE: A tool for estimating the military load classification of bridges using varying levels of information Van Groningen, C.N.; Paddock, R.A. (1997) 69 /> LLNL small-scale drop-hammer impact sensitivity test Simpson, L.R.; Foltz,

  15. PPPL's "Star Power" video offers compelling view of Laboratory's

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    research | Princeton Plasma Physics Lab PPPL's "Star Power" video offers compelling view of Laboratory's research By Jeanne Jackson DeVoe September 4, 2013 Tweet Widget Google Plus One Share on Facebook PPPL has released its new "Star Power" informational video. (Photo by Greg Czechowicz/PPPL Office of Communications ) PPPL has released its new "Star Power" informational video. (Watch video: http://www.pppl.gov/star%20power) The U.S. Department of Energy's

  16. DOE Zero Energy Ready Home Case Study: Clifton View Homes, Coupeville, WA,

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Systems Home | Department of Energy Coupeville, WA, Systems Home DOE Zero Energy Ready Home Case Study: Clifton View Homes, Coupeville, WA, Systems Home Case study of a DOE Zero Energy Ready Home on Whidbey Island, WA, that scored HERS 45 without PV. This 2,908-square-foot custom/system home has a SIP roof and walls, R-20 rigid foam under slab, triple-pane windows, ground source heat pump for radiant floor heat, and a unique balanced ventilation system using separate exhaust fans to bring

  17. DOE Zero Energy Ready Home Case Study: Clifton View Homes, Marine Drive and

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Port Hadlcok, Coupeville and Port Hadlock WA | Department of Energy Marine Drive and Port Hadlcok, Coupeville and Port Hadlock WA DOE Zero Energy Ready Home Case Study: Clifton View Homes, Marine Drive and Port Hadlcok, Coupeville and Port Hadlock WA Case study of two DOE 2015 Housing Innovation Award winning custom homes in the marine climate that got HERS 39 and 38 without PV or HERS 2-12 and -9 with PV, with 6.5" SIP walls and 10.25" SIP roof; 11.75 ICF around slab, R-20 rigid

  18. DOE Zero Energy Ready Home Case Study: Clifton View Homes, Whidbey Island,

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    WA | Department of Energy Whidbey Island, WA DOE Zero Energy Ready Home Case Study: Clifton View Homes, Whidbey Island, WA Case study of a DOE Zero Energy Ready home on Whidbey Island, WA, that scores HERS 37 without PV or HERS -13 with 10 kW PV, enough to power the home and an electric car. The two-story custom home has ICF below-grade walls, 6.5-inch SIP above-grade walls, a 10.25-in. SIP roof, and triple-pane windows. The home has a ground-source heat pump provides radiant floor heat

  19. Biomass stakeholder views and concerns: Environmental groups and some trade association

    SciTech Connect (OSTI)

    Peelle, E.

    2000-01-01

    This exploratory study of the views and concerns of 25 environmental organizations found high interest and concern about which biomass feedstocks would be used and how these biomass materials would be converted to energy. While all favored renewable energy over fossil or nuclear energy, opinion diverged over whether energy crops, residues, or both should be the primary source of a biomass/bioenergy fuel cycle. About half of the discussants favored biomass ``in general'' as a renewable energy source, while the others were distributed about equally over five categories, from favor-with-conditions, uncertain, skeptical, opposed, to ``no organizational policy.''

  20. Wind Energy Facilities and Residential Properties: The Effect of Proximity and View on Sales Prices

    SciTech Connect (OSTI)

    Hoen, Ben; Wiser, Ryan; Cappers, Peter; Thayer, Mark; Sethi, Gautam

    2010-04-01

    With an increasing number of communities considering nearby wind power developments, there is a need to empirically investigate community concerns about wind project development. One such concern is that property values may be adversely affected by wind energy facilities, and relatively little research exists on the subject. The present research investigates roughly 7,500 sales of single-family homes surrounding 24 existing U.S. wind facilities. Across four different hedonic models the results are consistent: neither the view of the wind facilities nor the distance of the home to those facilities is found to have a statistically significant effect on home sales prices.

  1. Consumer Views on Plug-in Electric Vehicles Â… National Benchmark Report

    Alternative Fuels and Advanced Vehicles Data Center [Office of Energy Efficiency and Renewable Energy (EERE)]

    Consumer Views on Plug-in Electric Vehicles - National Benchmark Report Mark Singer National Renewable Energy Laboratory Technical Report NREL/TP-5400-65279 January 2016 NREL is a national laboratory of the U.S. Department of Energy Office of Energy Efficiency & Renewable Energy Operated by the Alliance for Sustainable Energy, LLC This report is available at no cost from the National Renewable Energy Laboratory (NREL) at www.nrel.gov/publications. Contract No. DE-AC36-08GO28308 National

  2. September 2013 Most Viewed Documents for National Defense | OSTI, US Dept

    Office of Scientific and Technical Information (OSTI)

    of Energy, Office of Scientific and Technical Information September 2013 Most Viewed Documents for National Defense Science Subject Feed SMART BRIDGE: A tool for estimating the military load classification of bridges using varying levels of information Van Groningen, C.N.; Paddock, R.A. (1997) 34 /> Left-Wing Extremism: The Current Threat Karl A. Seger (2001) 28 /> The Elusive Coefficients of Thermal Expansion in PBX 9502 C.B. Skidmore; T.A. Butler; C.W. Sandoval (2003) 28 />

  3. September 2015 Most Viewed Documents for National Defense | OSTI, US Dept

    Office of Scientific and Technical Information (OSTI)

    of Energy, Office of Scientific and Technical Information September 2015 Most Viewed Documents for National Defense SMART BRIDGE: A tool for estimating the military load classification of bridges using varying levels of information Van Groningen, C.N.; Paddock, R.A. (1997) 131 Vapor-liquid equilibria for nitric acid-water and plutonium nitrate-nitric acid-water solutions Maimoni, A. (1980) 91 Smart bridge: a tool for estimating the military load classification of bridges Van Groningen, C.N.;

  4. January 2013 Most Viewed Documents for National Defense | OSTI, US Dept of

    Office of Scientific and Technical Information (OSTI)

    Energy, Office of Scientific and Technical Information January 2013 Most Viewed Documents for National Defense Dynamic equation of state and strength properties of unreacted PBXW-128 explosive Chhabildas, L.C.; Grady, D.E.; Reinhart, W.D.; Wilson, L.T. From separations to reconstitution - a short history of Plutonium in the U.S. and Russia Gray, L W Condensation induced water hammer safety Gintner, M.A. Direct calibration of the yield of nuclear explosion Nakanishi, K.; Nikolayev, A.

  5. June 2015 Most Viewed Documents for Renewable Energy Sources | OSTI, US

    Office of Scientific and Technical Information (OSTI)

    Dept of Energy, Office of Scientific and Technical Information June 2015 Most Viewed Documents for Renewable Energy Sources Wet cooling towers: rule-of-thumb design and simulation Leeper, S.A. (1981) 240 Aerodynamic characteristics of seven symmetrical airfoil sections through 180-degree angle of attack for use in aerodynamic analysis of vertical axis wind turbines Sheldahl, R E; Klimas, P C (1981) 192 Calculation of brine properties. [Above 80/sup 0/F and for salt content between 5 and 25%]

  6. March 2015 Most Viewed Documents for Biology And Medicine | OSTI, US Dept

    Office of Scientific and Technical Information (OSTI)

    of Energy, Office of Scientific and Technical Information 5 Most Viewed Documents for Biology And Medicine Measuring dopamine release in the human brain with PET Volkow, N.D. [Brookhaven National Lab., Upton, NY (United States)]|[State Univ. of New York at Stony Brook, Stony Brook, NY (United States). Dept. of Psychiatry]; Fowler, J.S.; Logan, J.; Wang, G.J. [Brookhaven National Lab., Upton, NY (United States)] (1995) 134 Drug Retention Times Center for Human Reliability Studies (2007) 114

  7. December 2015 Most Viewed Documents for Engineering | OSTI, US Dept of

    Office of Scientific and Technical Information (OSTI)

    Energy, Office of Scientific and Technical Information December 2015 Most Viewed Documents for Engineering Heat Treatment Procedure Qualification -- Final Technical Report Robert C. Voigt (2004) 776 Charpy impact test results on five materials and NIST verification specimens using instrumented 2-mm and 8-mm strikers Nanstad, R.K.; Sokolov, M.A. (1995) 546 Conduction heat transfer solutions VanSant, J.H. (1980) 527 Automotive vehicle sensors Sheen, S.H.; Raptis, A.C.; Moscynski, M.J. (1995)

  8. December 2015 Most Viewed Documents for National Defense | OSTI, US Dept of

    Office of Scientific and Technical Information (OSTI)

    Energy, Office of Scientific and Technical Information December 2015 Most Viewed Documents for National Defense SMART BRIDGE: A tool for estimating the military load classification of bridges using varying levels of information Van Groningen, C.N.; Paddock, R.A. (1997) 113 Comments on TNT Equivalence Cooper, P.W. (1994) 98 Vapor-liquid equilibria for nitric acid-water and plutonium nitrate-nitric acid-water solutions Maimoni, A. (1980) 82 The future of components for high reliability

  9. Wind Energy Facilities and Residential Properties: The Effect of Proximity and View on Sales Prices

    SciTech Connect (OSTI)

    San Diego State University; Bard Center for Environmental Policy at Bard College; Hoen, Ben; Wiser, Ryan; Cappers, Peter; Thayer, Mark; Sethi, Gautam

    2011-06-23

    With increasing numbers of communities considering wind power developments, empirical investigations regarding related community concerns are needed. One such concern is that proximate property values may be adversely affected, yet relatively little research exists on the subject. The present research investigates roughly 7,500 sales of single-family homes surrounding 24 existing U.S. wind facilities. Across four different hedonic models, and a variety of robustness tests, the results are consistent: neither the view of the wind facilities nor the distance of the home to those facilities is found to have a statistically significant effect on sales prices, yet further research is warranted.

  10. New Forces at Work in Mining: Industry View of Critical Technologies

    SciTech Connect (OSTI)

    Peterson, D. J.; LaTourrette, Tom; Bartis, James T.

    2007-04-01

    RAND has just published a report entitled, "New Forces at Work in Mining: Industry Views of Critical Technologies," by D. J. Peterson, Tom LaTourrette, and James T. Bartis. The report presents the results of a series of in-depth discussions with leading mining industry representatives selected for their prominent position and their ability to think broadly about technology trends. The discussions highlighted the importance of collaborative technology research, development, and implementation strategies and the increasingly critical role of mine personnel in the utilization of new technologies.

  11. Imaging Changes in Pediatric Intracranial Ependymoma Patients Treated With Proton Beam Radiation Therapy Compared to Intensity Modulated Radiation Therapy

    SciTech Connect (OSTI)

    Gunther, Jillian R.; Sato, Mariko; Chintagumpala, Murali; Ketonen, Leena; Jones, Jeremy Y.; Allen, Pamela K.; Paulino, Arnold C.; Okcu, M. Fatih; Su, Jack M.; Weinberg, Jeffrey; Boehling, Nicholas S.; Khatua, Soumen; Adesina, Adekunle; Dauser, Robert; Whitehead, William E.; Mahajan, Anita

    2015-09-01

    Purpose: The clinical significance of magnetic resonance imaging (MRI) changes after radiation therapy (RT) in children with ependymoma is not well defined. We compared imaging changes following proton beam radiation therapy (PBRT) to those after photon-based intensity modulated RT (IMRT). Methods and Materials: Seventy-two patients with nonmetastatic intracranial ependymoma who received postoperative RT (37 PBRT, 35 IMRT) were analyzed retrospectively. MRI images were reviewed by 2 neuroradiologists. Results: Sixteen PBRT patients (43%) developed postradiation MRI changes at 3.8 months (median) with resolution by 6.1 months. Six IMRT patients (17%) developed changes at 5.3 months (median) with 8.3 months to resolution. Mean age at radiation was 4.4 and 6.9 years for PBRT and IMRT, respectively (P=.06). Age at diagnosis (>3 years) and time of radiation (≥3 years) was associated with fewer imaging changes on univariate analysis (odds ratio [OR]: 0.35, P=.048; OR: 0.36, P=.05). PBRT (compared to IMRT) was associated with more frequent imaging changes, both on univariate (OR: 3.68, P=.019) and multivariate (OR: 3.89, P=.024) analyses. Seven (3 IMRT, 4 PBRT) of 22 patients with changes had symptoms requiring intervention. Most patients were treated with steroids; some PBRT patients also received bevacizumab and hyperbaric oxygen therapy. None of the IMRT patients had lasting deficits, but 2 patients died from recurrent disease. Three PBRT patients had persistent neurological deficits, and 1 child died secondarily to complications from radiation necrosis. Conclusions: Postradiation MRI changes are more common with PBRT and in patients less than 3 years of age at diagnosis and treatment. It is difficult to predict causes for development of imaging changes that progress to clinical significance. These changes are usually self-limiting, but some require medical intervention, especially those involving the brainstem.

  12. System and method for delivery of neutron beams for medical therapy

    DOE Patents [OSTI]

    Nigg, David W. (Idaho Falls, ID); Wemple, Charles A. (Idaho Falls, ID)

    1999-01-01

    A neutron delivery system that provides improved capability for tumor control during medical therapy. The system creates a unique neutron beam that has a bimodal or multi-modal energy spectrum. This unique neutron beam can be used for fast-neutron therapy, boron neutron capture therapy (BNCT), or both. The invention includes both an apparatus and a method for accomplishing the purposes of the invention.

  13. Metalloporphyrins and their uses as imageable tumor-targeting agents for radiation therapy

    DOE Patents [OSTI]

    Miura, Michiko; Slatkin, Daniel N.

    2003-05-20

    The present invention covers halogenated derivatives of boronated porphyrins containing multiple carborane cages having the formula ##STR1## which selectively accumulate in neoplastic tissue within the irradiation volume and thus can be used in cancer therapies including, but not limited to, boron neutron- capture therapy and photodynamic therapy. The present invention also covers methods for using these halogenated derivatives of boronated porphyrins in tumor imaging and cancer treatment.

  14. Use of novel metalloporphyrins as imageable tumor-targeting agents for radiation therapy

    DOE Patents [OSTI]

    Miura, Michiko; Slatkin, Daniel N.

    2005-10-04

    The present invention covers halogenated derivatives of boronated phorphyrins containing multiple carborane cages having the formula ##STR1## which selectively accumulate in neoplastic tissue within the irradiation volume and thus can be used in cancer therapies including, but not limited to, boron neutron-capture therapy and photodynamic therapy. The present invention also covers methods for using these halogenated derivatives of boronated porphyrins in tumor imaging and cancer treatment.

  15. System and method for delivery of neutron beams for medical therapy

    DOE Patents [OSTI]

    Nigg, D.W.; Wemple, C.A.

    1999-07-06

    A neutron delivery system that provides improved capability for tumor control during medical therapy is disclosed. The system creates a unique neutron beam that has a bimodal or multi-modal energy spectrum. This unique neutron beam can be used for fast-neutron therapy, boron neutron capture therapy (BNCT), or both. The invention includes both an apparatus and a method for accomplishing the purposes of the invention. 5 figs.

  16. On bolus for megavoltage photon and electron radiation therapy

    SciTech Connect (OSTI)

    Vyas, Vedang; Palmer, Lisa; Mudge, Ray; Jiang, Runqing; Fleck, Andre; Schaly, Bryan; Osei, Ernest; Charland, Paule

    2013-10-01

    Frequently, in radiation therapy one must treat superficial lesions on cancer patients; these are at or adjacent to the skin. Megavoltage photon radiotherapy penetrates through the skin to irradiate deep-seated tumors, with skin-sparing property. Hence, to treat superficial lesions, one must use a layer of scattering material to feign as the skin surface. Although megavoltage electron beams are used for superficial treatments, one occasionally needs to enhance the dose near the surface. Such is the function of a “bolus,” a natural or synthetically developed material that acts as a layer of tissue to provide a more effective treatment to the superficial lesions. Other uses of boluses are to correct for varying surface contours and to add scattering material around the patient's surface. Materials used as bolus vary from simple water to metal and include various mixtures and compounds. Even with the modernization of the technology for external-beam therapy and the emergence of various commercial boluses, the preparation and utilization of a bolus in clinical radiotherapy remains an art. Considering the varying experiences and practices, this paper briefly summarizes available boluses that have been proposed and are employed in clinical radiotherapy. Although this review is not exhaustive, it provides some initial guidance and answers questions that may arise in clinical practice.

  17. Improving superficial target delineation in radiation therapy with endoscopic tracking and registration

    SciTech Connect (OSTI)

    Weersink, R. A.; Qiu, J.; Hope, A. J.; Daly, M. J.; Cho, B. C. J.; DaCosta, R. S.; Sharpe, M. B.; Breen, S. L.; Chan, H.; Jaffray, D. A.

    2011-12-15

    Purpose: Target delineation within volumetric imaging is a critical step in the planning process of intensity modulated radiation therapy. In endoluminal cancers, endoscopy often reveals superficial areas of visible disease beyond what is seen on volumetric imaging. Quantitatively relating these findings to the volumetric imaging is prone to human error during the recall and contouring of the target. We have developed a method to improve target delineation in the radiation therapy planning process by quantitatively registering endoscopic findings contours traced on endoscopic images to volumetric imaging. Methods: Using electromagnetic sensors embedded in an endoscope, 2D endoscopic images were registered to computed tomography (CT) volumetric images by tracking the position and orientation of the endoscope relative to a CT image set. Regions-of-interest (ROI) in the 2D endoscopic view were delineated. A mesh created within the boundary of the ROI was projected onto the 3D image data, registering the ROI with the volumetric image. This 3D ROI was exported to clinical radiation treatment planning software. The precision and accuracy of the procedure was tested on two solid phantoms with superficial markings visible on both endoscopy and CT images. The first phantom was T-shaped tube with X-marks etched on the interior. The second phantom was an anatomically correct skull phantom with a phantom superficial lesion placed on the pharyngeal surface. Markings were contoured on the endoscope images and compared with contours delineated in the treatment planning system based on the CT images. Clinical feasibility was tested on three patients with early stage glottic cancer. Image-based rendering using manually identified landmarks was used to improve the registration. Results: Using the T-shaped phantom with X-markings, the 2D to 3D registration accuracy was 1.5-3.5 mm, depending on the endoscope position relative to the markings. Intraobserver standard variation was 0.5 mm. Rotational accuracy was within 2 deg. Using the skull phantom, registration accuracy was assessed by calculating the average surface minimum distance between the endoscopy and treatment planning contours. The average surface distance was 0.92 mm with 93% of all points in the 2D-endoscopy ROI within 1.5 mm of any point within the ROI contoured in the treatment planning software. This accuracy is limited by the CT imaging resolution and the electromagnetic (EM) sensor accuracy. The clinical testing demonstrated that endoscopic contouring is feasible. With registration based on em tracking only, accuracy was 5.6-8.4 mm. Image-based registration reduced this error to less than 3.5 mm and enabled endoscopic contouring in all cases. Conclusions: Registration of contours generated on 2D endoscopic images to 3D planning space is feasible, with accuracy smaller than typical set-up margins. Used in addition to standard 3D contouring methods in radiation planning, the technology may improve gross tumour volume (GTV) delineation for superficial tumors in luminal sites that are only visible in endoscopy.

  18. In-Situ Visualization Experiments with ParaView Cinema in RAGE

    SciTech Connect (OSTI)

    Kares, Robert John

    2015-10-15

    A previous paper described some numerical experiments performed using the ParaView/Catalyst in-situ visualization infrastructure deployed in the Los Alamos RAGE radiation-hydrodynamics code to produce images from a running large scale 3D ICF simulation. One challenge of the in-situ approach apparent in these experiments was the difficulty of choosing parameters likes isosurface values for the visualizations to be produced from the running simulation without the benefit of prior knowledge of the simulation results and the resultant cost of recomputing in-situ generated images when parameters are chosen suboptimally. A proposed method of addressing this difficulty is to simply render multiple images at runtime with a range of possible parameter values to produce a large database of images and to provide the user with a tool for managing the resulting database of imagery. Recently, ParaView/Catalyst has been extended to include such a capability via the so-called Cinema framework. Here I describe some initial experiments with the first delivery of Cinema and make some recommendations for future extensions of Cinema’s capabilities.

  19. Mass and Elite Views on Nuclear Security: US National Security Surveys 1993-1999

    SciTech Connect (OSTI)

    HERRON,KERRY G.; JENKINS-SMITH,HANK C.; HUGHES,SCOTT D.

    2000-06-01

    This is the fourth report in an ongoing series of studies examining how US perspectives about nuclear security are evolving in the post-Cold War era. In Volume 1 the authors present findings from a nationwide telephone survey of randomly selected members of the US general public conducted from 13 September to 14 October 1999. Results are compared to findings from previous surveys in this series conducted in 1993, 1995, and 1997, and trends are analyzed. Key areas of investigation reported in Volume 1 include evolving perceptions of nuclear weapons risks and benefits, preferences for related policy and spending issues, and views about three emerging issue areas: deterrent utility of precision guided munitions; response options to attacks in which mass casualty weapons are used; and expectations about national missile defenses. In this volume they relate respondent beliefs about nuclear security to perceptions of nuclear risks and benefits and to policy preferences. They develop causal models to partially explain key preferences, and they employ cluster analysis to group respondents into four policy relevant clusters characterized by similar views and preferences about nuclear security within each cluster. Systematic links are found among respondent demographic characteristics, perceptions of nuclear risks and benefits, policy beliefs, and security policy and spending preferences. In Volume 2 they provide analysis of in-depth interviews with fifty members of the US security policy community.

  20. Under-sodium viewing technology for improvement of fast-reactor safeguards

    SciTech Connect (OSTI)

    Beddingfield, David H; Gerhart, Jeremy J; Kawakubo, Yoko

    2009-01-01

    The current safeguards approach for fast reactors relies exclusively on maintenance of continuity of knowledge to track the movement of fuel assemblies through these facilities. The remote handling of fuel assemblies, the visual opacity of the liquid metal coolant. and the chemical reactivity of sodium all combine and result in significant limitations on the available options to verify fuel assembly identification numbers or the integrity of these assemblies. These limitations also serve to frustrate attempts to restore the continuity-of-knowledge in instances where the information is under a variety of scenarios. The technology of ultrasonic under-sodium viewing offers new options to the safeguards community for recovering continuity-of-knowledge and applying more traditional item accountancy to fast reactor facilities. We have performed a literature review to investigate the development of under-sodium viewing technologies. In this paper we will summarize our findings and report the state of development of this technology and we will present possible applications to the fast reactor system to improve the existing safeguards approach at these reactors and in future fast reactors.

  1. Wide-angle ITER-prototype tangential infrared and visible viewing system for DIII-D

    SciTech Connect (OSTI)

    Lasnier, C. J. Allen, S. L.; Ellis, R. E.; Fenstermacher, M. E.; McLean, A. G.; Meyer, W. H.; Morris, K.; Seppala, L. G.; Crabtree, K.; Van Zeeland, M. A.

    2014-11-15

    An imaging system with a wide-angle tangential view of the full poloidal cross-section of the tokamak in simultaneous infrared and visible light has been installed on DIII-D. The optical train includes three polished stainless steel mirrors in vacuum, which view the tokamak through an aperture in the first mirror, similar to the design concept proposed for ITER. A dichroic beam splitter outside the vacuum separates visible and infrared (IR) light. Spatial calibration is accomplished by warping a CAD-rendered image to align with landmarks in a data image. The IR camera provides scrape-off layer heat flux profile deposition features in diverted and inner-wall-limited plasmas, such as heat flux reduction in pumped radiative divertor shots. Demonstration of the system to date includes observation of fast-ion losses to the outer wall during neutral beam injection, and shows reduced peak wall heat loading with disruption mitigation by injection of a massive gas puff.

  2. Public views on multiple dimensions of security : nuclear waepons, terrorism, energy, and the environment : 2007.

    SciTech Connect (OSTI)

    Herron, Kerry Gale; Jenkins-Smith, Hank C.

    2008-01-01

    We analyze and compare findings from identical national surveys of the US general public on nuclear security and terrorism administered by telephone and Internet in mid-2007. Key areas of investigation include assessments of threats to US security; valuations of US nuclear weapons and nuclear deterrence; perspectives on nuclear proliferation, including the specific cases of North Korea and Iran; and support for investments in nuclear weapons capabilities. Our analysis of public views on terrorism include assessments of the current threat, progress in the struggle against terrorism, preferences for responding to terrorist attacks at different levels of assumed casualties, and support for domestic policies intended to reduce the threat of terrorism. Also we report findings from an Internet survey conducted in mid 2007 that investigates public views of US energy security, to include: energy supplies and reliability; energy vulnerabilities and threats, and relationships among security, costs, energy dependence, alternative sources, and research and investment priorities. We analyze public assessments of nuclear energy risks and benefits, nuclear materials management issues, and preferences for the future of nuclear energy in the US. Additionally, we investigate environmental issues as they relate to energy security, to include expected implications of global climate change, and relationships among environmental issues and potential policy options.

  3. An opposite view data replacement approach for reducing artifacts due to metallic dental objects

    SciTech Connect (OSTI)

    Yazdi, Mehran; Lari, Meghdad Asadi; Bernier, Gaston; Beaulieu, Luc

    2011-04-15

    Purpose: To present a conceptually new method for metal artifact reduction (MAR) that can be used on patients with multiple objects within the scan plane that are also of small sized along the longitudinal (scanning) direction, such as dental fillings. Methods: The proposed algorithm, named opposite view replacement, achieves MAR by first detecting the projection data affected by metal objects and then replacing the affected projections by the corresponding opposite view projections, which are not affected by metal objects. The authors also applied a fading process to avoid producing any discontinuities in the boundary of the affected projection areas in the sinogram. A skull phantom with and without a variety of dental metal inserts was made to extract the performance metric of the algorithm. A head and neck case, typical of IMRT planning, was also tested. Results: The reconstructed CT images based on this new replacement scheme show a significant improvement in image quality for patients with metallic dental objects compared to the MAR algorithms based on the interpolation scheme. For the phantom, the authors showed that the artifact reduction algorithm can efficiently recover the CT numbers in the area next to the metallic objects. Conclusions: The authors presented a new and efficient method for artifact reduction due to multiple small metallic objects. The obtained results from phantoms and clinical cases fully validate the proposed approach.

  4. Carcinoma of the anal canal: Intensity modulated radiation therapy (IMRT) versus three-dimensional conformal radiation therapy (3DCRT)

    SciTech Connect (OSTI)

    Sale, Charlotte; Moloney, Phillip; Mathlum, Maitham

    2013-12-15

    Patients with anal canal carcinoma treated with standard conformal radiotherapy frequently experience severe acute and late toxicity reactions to the treatment area. Roohipour et al. (Dis Colon Rectum 2008; 51: 147–53) stated a patient's tolerance of chemoradiation to be an important prediction of treatment success. A new intensity modulated radiation therapy (IMRT) technique for anal carcinoma cases has been developed at the Andrew Love Cancer Centre aimed at reducing radiation to surrounding healthy tissue. A same-subject repeated measures design was used for this study, where five anal carcinoma cases at the Andrew Love Cancer Centre were selected. Conformal and IMRT plans were generated and dosimetric evaluations were performed. Each plan was prescribed a total of 54 Gray (Gy) over a course of 30 fractions to the primary site. The IMRT plans resulted in improved dosimetry to the planning target volume (PTV) and reduction in radiation to the critical structures (bladder, external genitalia and femoral heads). Statistically there was no difference between the IMRT and conformal plans in the dose to the small and large bowel; however, the bowel IMRT dose–volume histogram (DVH) doses were consistently lower. The IMRT plans were superior to the conformal plans with improved dose conformity and reduced radiation to the surrounding healthy tissue. Anecdotally it was found that patients tolerated the IMRT treatment better than the three-dimensional (3D) conformal radiation therapy. This study describes and compares the planning techniques.

  5. Stereotactic Ablative Radiation Therapy as First Local Therapy for Lung Oligometastases From Colorectal Cancer: A Single-Institution Cohort Study

    SciTech Connect (OSTI)

    Filippi, Andrea Riccardo; Badellino, Serena; Ceccarelli, Manuela; Guarneri, Alessia; Franco, Pierfrancesco; Monagheddu, Chiara; Spadi, Rosella; Ragona, Riccardo; Racca, Patrizia; Ricardi, Umberto

    2015-03-01

    Purpose: To estimate stereotactic ablative radiation therapy (SABR) efficacy and its potential role as an alternative to surgery for the treatment of lung metastases from colorectal cancer. Methods and Materials: Forty consecutive patients who received SABR as first local therapy at the time of lung progression were included, from 2004 to 2014. The primary study endpoint was overall survival. Secondary endpoints were progression-free survival and safety. Results: A single nodule was treated in 26 patients (65%), 2 nodules in 10 patients (25%), 3 in 3 patients (7.5%), and 4 in 1 patient (2.5%), for a total of 59 lesions. The median delivered biological effective dose was 96 Gy, in 1 to 8 daily fractions. Median follow-up time was 20 months (range, 3-72 months). Overall survival rates at 1, 2, and 5 years were, respectively, 84%, 73%, and 39%, with 14 patients (35%) dead. Median overall survival was 46 months. Progression occurred in 25 patients (62.5%), at a median interval of 8 months; failure at SABR site was observed in 3 patients (7.5%). Progression-free survival rates were 49% and 27% at 1 and 2 years, respectively. Discussion: The results of this retrospective exploratory analysis suggest safety and efficacy of SABR in patients affected with colorectal cancer lung oligometastases and urge inclusion of SABR in prospective clinical trials.

  6. Proton Beam Therapy Versus Conformal Photon Radiation Therapy for Childhood Craniopharyngioma: Multi-institutional Analysis of Outcomes, Cyst Dynamics, and Toxicity

    SciTech Connect (OSTI)

    Bishop, Andrew J.; Greenfield, Brad; Mahajan, Anita; Paulino, Arnold C.; Okcu, M. Fatih; Allen, Pamela K.; Chintagumpala, Murali; Kahalley, Lisa S.; McAleer, Mary F.; McGovern, Susan L.; Whitehead, William E.; Grosshans, David R.

    2014-10-01

    Purpose: We compared proton beam therapy (PBT) with intensity modulated radiation therapy (IMRT) for pediatric craniopharyngioma in terms of disease control, cyst dynamics, and toxicity. Methods and Materials: We reviewed records from 52 children treated with PBT (n=21) or IMRT (n=31) at 2 institutions from 1996-2012. Endpoints were overall survival (OS), disease control, cyst dynamics, and toxicity. Results: At 59.6 months' median follow-up (PBT 33 mo vs IMRT 106 mo; P<.001), the 3-year outcomes were 96% for OS, 95% for nodular failure-free survival and 76% for cystic failure-free survival. Neither OS nor disease control differed between treatment groups (OS P=.742; nodular failure-free survival P=.546; cystic failure-free survival P=.994). During therapy, 40% of patients had cyst growth (20% requiring intervention); immediately after therapy, 17 patients (33%) had cyst growth (transient in 14), more commonly in the IMRT group (42% vs 19% PBT; P=.082); and 27% experienced late cyst growth (32% IMRT, 19% PBT; P=.353), with intervention required in 40%. Toxicity did not differ between groups. On multivariate analysis, cyst growth was related to visual and hypothalamic toxicity (P=.009 and .04, respectively). Patients given radiation as salvage therapy (for recurrence) rather than adjuvant therapy had higher rates of visual and endocrine (P=.017 and .024, respectively) dysfunction. Conclusions: Survival and disease-control outcomes were equivalent for PBT and IMRT. Cyst growth is common, unpredictable, and should be followed during and after therapy, because it contributes to late toxicity. Delaying radiation therapy until recurrence may result in worse visual and endocrine function.

  7. Cyclotron Produced Radionuclides for Diagnosis and Therapy of Human Neoplasms

    SciTech Connect (OSTI)

    Steven Larson MD

    2009-09-21

    This project funded since 1986 serves as a core project for cancer research throughout MSKCC, producing key radiotracers as well as basic knowledge about thel physics of radiation decay and imaging, for nuclear medicine applications to cancer diagnosis and therapy. In recent years this research application has broadened to include experiments intended to lead to an improved understanding of cancer biology and into the discovery and testing of new cancer drugs. Advances in immune based radiotargeting form the basis for this project. Both antibody and cellular based immune targeting methods have been explored. The multi-step targeting methodologies (MST) developed by NeoRex (Seattle,Washington), have been adapted for use with positron emitting isotopes and PET allowing the quantification and optimization of targeted delivery. In addition, novel methods for radiolabeling immune T-cells with PET tracers have advanced our ability to track these cells of prolonged period of time.

  8. Delineation of Supraclavicular Target Volumes in Breast Cancer Radiation Therapy

    SciTech Connect (OSTI)

    Brown, Lindsay C.; Diehn, Felix E.; Boughey, Judy C.; Childs, Stephanie K.; Park, Sean S.; Yan, Elizabeth S.; Petersen, Ivy A.; Mutter, Robert W.

    2015-07-01

    Purpose: To map the location of gross supraclavicular metastases in patients with breast cancer, in order to determine areas at highest risk of harboring subclinical disease. Methods and Materials: Patients with axial imaging of gross supraclavicular disease were identified from an institutional breast cancer registry. Locations of the metastatic lymph nodes were transferred onto representative axial computed tomography images of the supraclavicular region and compared with the Radiation Therapy Oncology Group (RTOG) breast cancer atlas for radiation therapy planning. Results: Sixty-two patients with 161 supraclavicular nodal metastases were eligible for study inclusion. At the time of diagnosis, 117 nodal metastases were present in 44 patients. Forty-four nodal metastases in 18 patients were detected at disease recurrence, 4 of whom had received prior radiation to the supraclavicular fossa. Of the 161 nodal metastases, 95 (59%) were within the RTOG consensus volume, 4 nodal metastases (2%) in 3 patients were marginally within the volume, and 62 nodal metastases (39%) in 30 patients were outside the volume. Supraclavicular disease outside the RTOG consensus volume was located in 3 regions: at the level of the cricoid and thyroid cartilage (superior to the RTOG volume), in the posterolateral supraclavicular fossa (posterolateral to the RTOG volume), and in the lateral low supraclavicular fossa (lateral to the RTOG volume). Only women with multiple supraclavicular metastases had nodal disease that extended superiorly to the level of the thyroid cartilage. Conclusions: For women with risk of harboring subclinical supraclavicular disease warranting the addition of supraclavicular radiation, coverage of the posterior triangle and the lateral low supraclavicular region should be considered. For women with known supraclavicular disease, extension of neck coverage superior to the cricoid cartilage may be warranted.

  9. Measurements and simulations of focused beam for orthovoltage therapy

    SciTech Connect (OSTI)

    Abbas, Hassan; Mahato, Dip N.; Satti, Jahangir; MacDonald, C. A.

    2014-04-15

    Purpose: Megavoltage photon beams are typically used for therapy because of their skin-sparing effect. However, a focused low-energy x-ray beam would also be skin sparing, and would have a higher dose concentration at the focal spot. Such a beam can be produced with polycapillary optics. MCNP5 was used to model dose profiles for a scanned focused beam, using measured beam parameters. The potential of low energy focused x-ray beams for radiation therapy was assessed. Methods: A polycapillary optic was used to focus the x-ray beam from a tungsten source. The optic was characterized and measurements were performed at 50 kV. PMMA blocks of varying thicknesses were placed between optic and the focal spot to observe any variation in the focusing of the beam after passing through the tissue-equivalent material. The measured energy spectrum was used to model the focused beam in MCNP5. A source card (SDEF) in MCNP5 was used to simulate the converging x-ray beam. Dose calculations were performed inside a breast tissue phantom. Results: The measured focal spot size for the polycapillary optic was 0.2 mm with a depth of field of 5 mm. The measured focal spot remained unchanged through 40 mm of phantom thickness. The calculated depth dose curve inside the breast tissue showed a dose peak several centimeters below the skin with a sharp dose fall off around the focus. The percent dose falls below 10% within 5 mm of the focus. It was shown that rotating the optic during scanning would preserve the skin-sparing effect of the focused beam. Conclusions: Low energy focused x-ray beams could be used to irradiate tumors inside soft tissue within 5 cm of the surface.

  10. Dosimetrically Triggered Adaptive Intensity Modulated Radiation Therapy for Cervical Cancer

    SciTech Connect (OSTI)

    Lim, Karen; Stewart, James; Kelly, Valerie; Xie, Jason; Brock, Kristy K.; Moseley, Joanne; Cho, Young-Bin; Fyles, Anthony; Lundin, Anna; Rehbinder, Henrik; Löf, Johan; Jaffray, David A.; Milosevic, Michael

    2014-09-01

    Purpose: The widespread use of intensity modulated radiation therapy (IMRT) for cervical cancer has been limited by internal target and normal tissue motion. Such motion increases the risk of underdosing the target, especially as planning margins are reduced in an effort to reduce toxicity. This study explored 2 adaptive strategies to mitigate this risk and proposes a new, automated method that minimizes replanning workload. Methods and Materials: Thirty patients with cervical cancer participated in a prospective clinical study and underwent pretreatment and weekly magnetic resonance (MR) scans over a 5-week course of daily external beam radiation therapy. Target volumes and organs at risk (OARs) were contoured on each of the scans. Deformable image registration was used to model the accumulated dose (the real dose delivered to the target and OARs) for 2 adaptive replanning scenarios that assumed a very small PTV margin of only 3 mm to account for setup and internal interfractional motion: (1) a preprogrammed, anatomy-driven midtreatment replan (A-IMRT); and (2) a dosimetry-triggered replan driven by target dose accumulation over time (D-IMRT). Results: Across all 30 patients, clinically relevant target dose thresholds failed for 8 patients (27%) if 3-mm margins were used without replanning. A-IMRT failed in only 3 patients and also yielded an additional small reduction in OAR doses at the cost of 30 replans. D-IMRT assured adequate target coverage in all patients, with only 23 replans in 16 patients. Conclusions: A novel, dosimetry-triggered adaptive IMRT strategy for patients with cervical cancer can minimize the risk of target underdosing in the setting of very small margins and substantial interfractional motion while minimizing programmatic workload and cost.

  11. Versioned distributed arrays for resilience in scientific applications: Global view resilience

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Chien, A.; Balaji, P.; Beckman, P.; Dun, N.; Fang, A.; Fujita, H.; Iskra, K.; Rubenstein, Z.; Zheng, Z.; Schreiber, R.; et al

    2015-06-01

    Exascale studies project reliability challenges for future high-performance computing (HPC) systems. We propose the Global View Resilience (GVR) system, a library that enables applications to add resilience in a portable, application-controlled fashion using versioned distributed arrays. We describe GVR’s interfaces to distributed arrays, versioning, and cross-layer error recovery. Using several large applications (OpenMC, the preconditioned conjugate gradient solver PCG, ddcMD, and Chombo), we evaluate the programmer effort to add resilience. The required changes are small (<2% LOC), localized, and machine-independent, requiring no software architecture changes. We also measure the overhead of adding GVR versioning and show that generally overheads <2%more » are achieved. We conclude that GVR’s interfaces and implementation are flexible and portable and create a gentle-slope path to tolerate growing error rates in future systems.« less

  12. A Global View Programming Abstraction for Transitioning MPI Codes to PGAS Languages

    SciTech Connect (OSTI)

    Mintz, Tiffany M [ORNL] [ORNL; Hernandez, Oscar R [ORNL] [ORNL; Bernholdt, David E [ORNL] [ORNL

    2014-01-01

    The multicore generation of scientific high performance computing has provided a platform for the realization of Exascale computing, and has also underscored the need for new paradigms in coding parallel applications. The current standard for writing parallel applications requires programmers to use languages designed for sequential execution. These languages have abstractions that only allow programmers to operate on the process centric local view of data. To provide suitable languages for parallel execution, many research efforts have designed languages based on the Partitioned Global Address Space (PGAS) programming model. Chapel is one of the more recent languages to be developed using this model. Chapel supports multithreaded execution with high-level abstractions for parallelism. With Chapel in mind, we have developed a set of directives that serve as intermediate expressions for transitioning scientific applications from languages designed for sequential execution to PGAS languages like Chapel that are being developed with parallelism in mind.

  13. Wind Energy Facilities and Residential Properties: The Effect of Proximity and View on Sales Prices

    SciTech Connect (OSTI)

    Hoen, Ben; Wiser, Ryan; Cappers, Peter; Thayer, Mark; Sethi, Gautam

    2010-04-01

    With wind energy expanding rapidly in the U.S. and abroad, and with an increasing number of communities considering nearby wind power developments, there is a need to empirically investigate community concerns about wind project development. One such concern is that property values may be adversely affected by wind energy facilities, and relatively little existing research exists on the subject. The present research is based on almost 7,500 sales of single-family homes situated within ten miles of 24 existing wind facilities in nine different U.S. states. The conclusions of the study are drawn from four different hedonic pricing models. The model results are consistent in that neither the view of the wind facilities nor the distance of the home to those facilities is found to have a statistically significant effect on home sales prices.

  14. Visible wide angle view imaging system of KTM tokamak based on multielement image fiber bundle

    SciTech Connect (OSTI)

    Chektybayev, B. Shapovalov, G.; Kolodeshnikov, A.

    2015-05-15

    In the paper, new visible wide angle view imaging system of KTM tokamak is described. The system has been designed to observe processes inside of plasma and the processes occurring due to plasma-wall interactions through the long equatorial port. Imaging system is designed based on special image fiber bundle and entrance wide angle lens, which provide image of large section of the vacuum chamber, both poloidal half-section and divertor through the sufficiently long equatorial port. The system also consists of two video cameras: slow and fast with image intensifier. Commercial equipment had been used in design of the system that allowed reducing the cost and time for research and development. The paper also discusses advantages and disadvantages of the system in comparison with conventional endoscopes based on a lens system and considers its promising utilization in future tokamaks and future steady state fusion reactors.

  15. Versioned distributed arrays for resilience in scientific applications: Global view resilience

    SciTech Connect (OSTI)

    Chien, A.; Balaji, P.; Beckman, P.; Dun, N.; Fang, A.; Fujita, H.; Iskra, K.; Rubenstein, Z.; Zheng, Z.; Schreiber, R.; Hammond, J.; Dinan, J.; Laguna, I.; Richards, D.; Dubey, A.; van Straalen, B.; Hoemmen, M.; Heroux, M.; Teranishi, K.; Siegel, A.

    2015-06-01

    Exascale studies project reliability challenges for future high-performance computing (HPC) systems. We propose the Global View Resilience (GVR) system, a library that enables applications to add resilience in a portable, application-controlled fashion using versioned distributed arrays. We describe GVR’s interfaces to distributed arrays, versioning, and cross-layer error recovery. Using several large applications (OpenMC, the preconditioned conjugate gradient solver PCG, ddcMD, and Chombo), we evaluate the programmer effort to add resilience. The required changes are small (<2% LOC), localized, and machine-independent, requiring no software architecture changes. We also measure the overhead of adding GVR versioning and show that generally overheads <2% are achieved. We conclude that GVR’s interfaces and implementation are flexible and portable and create a gentle-slope path to tolerate growing error rates in future systems.

  16. Siting landfills and incinerators in areas of historic unpopularity: Surveying the views of the next generation

    SciTech Connect (OSTI)

    De Feo, Giovanni; Williams, Ian D.

    2013-12-15

    Highlights: • Opinions and knowledge of young people in Italy about waste were studied. • Historic opposition to construction of waste facilities is difficult to overcome. • Awareness of waste management develops with knowledge of environmental issues. • Many stakeholders’ views are needed when siting a new waste management facility. • Respondents’ opinions were influenced by their level of environmental knowledge. - Abstract: The Campania Region in Southern Italy has suffered many problems with municipal solid waste management since the mid-1990s, leading to significant public disturbances and subsequent media coverage. This paper reports on the current views and knowledge of young people (university students) in this region about waste management operations and facilities, specifically the siting of landfills and incinerators. By means of a structured questionnaire, opinion and knowledge were systematically examined by degree type and course year. The study took place in 2011 at the University of Salerno campus. A sample of 900 students, comprising 100 students for each of the nine considered faculties, and 20 students for every academic course year, was randomly selected. Only about a quarter of respondents were not opposed to the siting of a landfill or an incinerator in their city. This clearly highlights that historic opposition to the construction of waste facilities is difficult to overcome and that distrust for previous poor management or indiscretions is long-lived and transcends generations. Students from technical faculties expressed the most reasonable opinion; opinion and knowledge were statistically related (Chi-square test, p < 0.05) to the attended faculty, and the knowledge grew linearly with progression through the university. This suggests that awareness of waste management practices develops with experience and understanding of environmental issues. There is general acceptance that many stakeholders – technicians, politicians and citizens – all have to be part of the decision process when siting a new waste management facility. The opinions of the young respondents were significantly influenced by their level of environmental knowledge.

  17. On the operation of X-ray polarimeters with a large field of view

    SciTech Connect (OSTI)

    Muleri, Fabio, E-mail: fabio.muleri@iaps.inaf.it [INAF-IAPS, Via del Fosso del Cavaliere 100, I-00133 Roma (Italy)

    2014-02-10

    The measurement of linear polarization is one of the hot topics of high-energy astrophysics. Gas detectors based on the photoelectric effect have paved the way for the design of sensitive instruments, and mission proposals based on them have been presented in the last few years in the energy range from about 2 keV to a few tens of keV. In addition, a number of polarimeters based on Compton scattering are approved or being discussed for launch on board balloons or space satellites at higher energies. These instruments are typically dedicated to pointed observations with narrow field of view telescopes or collimators, but there are also projects aimed at the polarimetry of bright transient sources such as soft gamma repeaters or the prompt emission of gamma-ray bursts. Given the erratic appearance of such events in the sky, these polarimeters have large fields of view to catch a reasonable number of them, and as a result, photons may impinge on the detector off-axis. This dramatically changes the response of the instrument to polarization, regardless of whether photoabsorption or Compton scattering is involved. Instead of the simple cosine-squared dependence expected for polarized photons that are incident on-axis, the response is never purely cosinusoidal, and a systematic modulation also appears for unpolarized radiation. We investigate the origin of these differences and present an analytical treatment that proves that such systematic effects are actually a natural consequence of how current instruments operate. Our analysis provides the expected response of photoelectric or Compton polarimeters to photons impinging with any inclination and state of polarization.

  18. A MULTI-SPACECRAFT VIEW OF A GIANT FILAMENT ERUPTION DURING 2009 SEPTEMBER 26/27

    SciTech Connect (OSTI)

    Gosain, Sanjay; Schmieder, Brigitte; Artzner, Guy; Bogachev, Sergei; Toeroek, Tibor

    2012-12-10

    We analyze multi-spacecraft observations of a giant filament eruption that occurred during 2009 September 26 and 27. The filament eruption was associated with a relatively slow coronal mass ejection. The filament consisted of a large and a small part, and both parts erupted nearly simultaneously. Here we focus on the eruption associated with the larger part of the filament. The STEREO satellites were separated by about 117 Degree-Sign during this event, so we additionally used SoHO/EIT and CORONAS/TESIS observations as a third eye (Earth view) to aid our measurements. We measure the plane-of-sky trajectory of the filament as seen from STEREO-A and TESIS viewpoints. Using a simple trigonometric relation, we then use these measurements to estimate the true direction of propagation of the filament which allows us to derive the true R/R{sub Sun }-time profile of the filament apex. Furthermore, we develop a new tomographic method that can potentially provide a more robust three-dimensional (3D) reconstruction by exploiting multiple simultaneous views. We apply this method also to investigate the 3D evolution of the top part of filament. We expect this method to be useful when SDO and STEREO observations are combined. We then analyze the kinematics of the eruptive filament during its rapid acceleration phase by fitting different functional forms to the height-time data derived from the two methods. We find that for both methods an exponential function fits the rise profile of the filament slightly better than parabolic or cubic functions. Finally, we confront these results with the predictions of theoretical eruption models.

  19. Cost-Effectiveness Analysis of Intensity Modulated Radiation Therapy Versus 3-Dimensional Conformal Radiation Therapy for Anal Cancer

    SciTech Connect (OSTI)

    Hodges, Joseph C.; Beg, Muhammad S.; Das, Prajnan; Meyer, Jeffrey

    2014-07-15

    Purpose: To compare the cost-effectiveness of intensity modulated radiation therapy (IMRT) and 3-dimensional conformal radiation therapy (3D-CRT) for anal cancer and determine disease, patient, and treatment parameters that influence the result. Methods and Materials: A Markov decision model was designed with the various disease states for the base case of a 65-year-old patient with anal cancer treated with either IMRT or 3D-CRT and concurrent chemotherapy. Health states accounting for rates of local failure, colostomy failure, treatment breaks, patient prognosis, acute and late toxicities, and the utility of toxicities were informed by existing literature and analyzed with deterministic and probabilistic sensitivity analysis. Results: In the base case, mean costs and quality-adjusted life expectancy in years (QALY) for IMRT and 3D-CRT were $32,291 (4.81) and $28,444 (4.78), respectively, resulting in an incremental cost-effectiveness ratio of $128,233/QALY for IMRT compared with 3D-CRT. Probabilistic sensitivity analysis found that IMRT was cost-effective in 22%, 47%, and 65% of iterations at willingness-to-pay thresholds of $50,000, $100,000, and $150,000 per QALY, respectively. Conclusions: In our base model, IMRT was a cost-ineffective strategy despite the reduced acute treatment toxicities and their associated costs of management. The model outcome was sensitive to variations in local and colostomy failure rates, as well as patient-reported utilities relating to acute toxicities.

  20. Nomograms Predicting Response to Therapy and Outcomes After Bladder-Preserving Trimodality Therapy for Muscle-Invasive Bladder Cancer

    SciTech Connect (OSTI)

    Coen, John J.; Paly, Jonathan J.; Niemierko, Andrzej; Kaufman, Donald S.; Heney, Niall M.; Spiegel, Daphne Y.; Efstathiou, Jason A.; Zietman, Anthony L.; Shipley, William U.

    2013-06-01

    Purpose: Selective bladder preservation by use of trimodality therapy is an established management strategy for muscle-invasive bladder cancer. Individual disease features have been associated with response to therapy, likelihood of bladder preservation, and disease-free survival. We developed prognostic nomograms to predict the complete response rate, disease-specific survival, and likelihood of remaining free of recurrent bladder cancer or cystectomy. Methods and Materials: From 1986 to 2009, 325 patients were managed with selective bladder preservation at Massachusetts General Hospital (MGH) and had complete data adequate for nomogram development. Treatment consisted of a transurethral resection of bladder tumor followed by split-course chemoradiation. Patients with a complete response at midtreatment cystoscopic assessment completed radiation, whereas those with a lesser response underwent a prompt cystectomy. Prognostic nomograms were constructed predicting complete response (CR), disease-specific survival (DSS), and bladder-intact disease-free survival (BI-DFS). BI-DFS was defined as the absence of local invasive or regional recurrence, distant metastasis, bladder cancer-related death, or radical cystectomy. Results: The final nomograms included information on clinical T stage, presence of hydronephrosis, whether a visibly complete transurethral resection of bladder tumor was performed, age, sex, and tumor grade. The predictive accuracy of these nomograms was assessed. For complete response, the area under the receiving operating characteristic curve was 0.69. The Harrell concordance index was 0.61 for both DSS and BI-DFS. Conclusions: Our nomograms allow individualized estimates of complete response, DSS, and BI-DFS. They may assist patients and clinicians making important treatment decisions.

  1. Adjuvant Radiation Therapy Treatment Time Impacts Overall Survival in Gastric Cancer

    SciTech Connect (OSTI)

    McMillan, Matthew T.; Ojerholm, Eric; Roses, Robert E.; Plastaras, John P.; Metz, James M.; Mamtani, Ronac; Stripp, Diana; Ben-Josef, Edgar; Datta, Jashodeep

    2015-10-01

    Purpose: Prolonged radiation therapy treatment time (RTT) is associated with worse survival in several tumor types. This study investigated whether delays during adjuvant radiation therapy impact overall survival (OS) in gastric cancer. Methods and Materials: The National Cancer Data Base was queried for patients with resected gastric cancer who received adjuvant radiation therapy with National Comprehensive Cancer Network–recommended doses (45 or 50.4 Gy) between 1998 and 2006. RTT was classified as standard (45 Gy: 33-36 days, 50.4 Gy: 38-41 days) or prolonged (45 Gy: >36 days, 50.4 Gy: >41 days). Cox proportional hazards models evaluated the association between the following factors and OS: RTT, interval from surgery to radiation therapy initiation, interval from surgery to radiation therapy completion, radiation therapy dose, demographic/pathologic and operative factors, and other elements of adjuvant multimodality therapy. Results: Of 1591 patients, RTT was delayed in 732 (46%). Factors associated with prolonged RTT were non-private health insurance (OR 1.3, P=.005) and treatment at non-academic facilities (OR 1.2, P=.045). Median OS and 5-year actuarial survival were significantly worse in patients with prolonged RTT compared with standard RTT (36 vs 51 months, P=.001; 39 vs 47%, P=.005); OS worsened with each cumulative week of delay (P<.0004). On multivariable analysis, prolonged RTT was associated with inferior OS (hazard ratio 1.2, P=.002); the intervals from surgery to radiation therapy initiation or completion were not. Prolonged RTT was particularly detrimental in patients with node positivity, inadequate nodal staging (<15 nodes examined), and those undergoing a cycle of chemotherapy before chemoradiation therapy. Conclusions: Delays during adjuvant radiation therapy appear to negatively impact survival in gastric cancer. Efforts to minimize cumulative interruptions to <7 days should be considered.

  2. Prairie View A&M Tops 2016 U.S. Department of Energy Race to Zero Student

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Design Competition | Department of Energy Prairie View A&M Tops 2016 U.S. Department of Energy Race to Zero Student Design Competition Prairie View A&M Tops 2016 U.S. Department of Energy Race to Zero Student Design Competition April 22, 2016 - 3:00pm Addthis As part of the Obama Administration's commitment to helping families across the United States save money by saving energy, the U.S. Department of Energy announced winners of its third annual Race to Zero Student Design

  3. Effects of Surgery and Proton Therapy on Cerebral White Matter of Craniopharyngioma Patients

    SciTech Connect (OSTI)

    Uh, Jinsoo; Merchant, Thomas E.; Li, Yimei; Li, Xingyu; Sabin, Noah D.; Indelicato, Daniel J.; Ogg, Robert J.; Boop, Frederick A.; Jane, John A.; Hua, Chiaho

    2015-09-01

    Purpose: The purpose of this study was to determine radiation dose effect on the structural integrity of cerebral white matter in craniopharyngioma patients receiving surgery and proton therapy. Methods and Materials: Fifty-one patients (2.1-19.3 years of age) with craniopharyngioma underwent surgery and proton therapy in a prospective therapeutic trial. Anatomical magnetic resonance images acquired after surgery but before proton therapy were inspected to identify white matter structures intersected by surgical corridors and catheter tracks. Longitudinal diffusion tensor imaging (DTI) was performed to measure microstructural integrity changes in cerebral white matter. Fractional anisotropy (FA) derived from DTI was statistically analyzed for 51 atlas-based white matter structures of the brain to determine radiation dose effect. FA in surgery-affected regions in the corpus callosum was compared to that in its intact counterpart to determine whether surgical defects affect radiation dose effect. Results: Surgical defects were seen most frequently in the corpus callosum because of transcallosal resection of tumors and insertion of ventricular or cyst catheters. Longitudinal DTI data indicated reductions in FA 3 months after therapy, which was followed by a recovery in most white matter structures. A greater FA reduction was correlated with a higher radiation dose in 20 white matter structures, indicating a radiation dose effect. The average FA in the surgery-affected regions before proton therapy was smaller (P=.0001) than that in their non–surgery-affected counterparts with more intensified subsequent reduction of FA (P=.0083) after therapy, suggesting that surgery accentuated the radiation dose effect. Conclusions: DTI data suggest that mild radiation dose effects occur in patients with craniopharyngioma receiving surgery and proton therapy. Surgical defects present at the time of proton therapy appear to accentuate the radiation dose effect longitudinally. This study supports consideration of pre-existing surgical defects and their locations in proton therapy planning and studies of treatment effect.

  4. Characterization of a constrained paired-view technique in iterative reconstruction for breast tomosynthesis

    SciTech Connect (OSTI)

    Wu, Gang; Yaffe, Martin J.; Mainprize, James G.

    2013-10-15

    Purpose: The order in which the projection views are employed in the reconstruction of tomosynthesis by iterative algorithms, such as simultaneous algebraic reconstruction technique and maximum likelihood, has a strong effect on the rate of convergence, accuracy, and the edge-blurring artifacts in the reconstructed image. The purpose of this investigation was to characterize and evaluate the effects of ordering schemes on image quality for breast tomosynthesis reconstruction and to explore a new constrained paired-view technique that could provide reduction of reconstruction artifacts. In this work, the authors compared several different ordering schemes and characterized the image quality and the formation of out-of-plane artifacts. Furthermore, a new normalization method is presented. It produces more accurate reconstructions with reduced artifacts comparing to the standard method of sequential ordering.Methods: In addition to visual assessment of image quality, several indices such as the signal-difference-to-noise ratio, the artifact-spread function, and the lesion detectability (d{sup ?}) were computed to quantitatively evaluate the effect of ordering scheme. The sets of breast tomosynthesis projection images were simulated for reconstruction; one set had uniform background (white noise only) and the other two contained both anatomic background and quantum noise. Clinical breast images were also studied for comparison.Results: The authors have quantified the image quality in reconstructed slices for a range of tumor sizes. The authors’ proposed method provides better performance for all of the metrics tested (contrast, d{sup ?}, and the level of artifacts) both for the uniform phantom case and in the presence of anatomical structure.Conclusions: The paired projection normalization provides better performance in the image quality of the reconstructed slices, and results in a lower level of artifacts in the Z direction. This implies that even a relatively simple method like the “side-to-side” sequence, which pairs two symmetrical projections with equal angular distance from the central projection, would achieve better reconstructed image quality than the conventional “step-by-step” method, which uses sequential projections one after another.

  5. Osteogenic Sarcoma of the Maxilla: Neutron Therapy for Unresectable Disease

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Smoron, Geoffrey L.; Lennox, Arlene J.; Mcgee, James L.

    1999-01-01

    Purpose. To present a case study involving the use of fast neutron therapy to treat an extensive unresectable osteogenic sarcoma arising from the left maxilla. Patient. A 14-year-old male presented with a massive tumor producing severe distortion of his facial structures. He had already received six courses of chemotherapy, which had reduced his pain, but had not measurably reduced the tumor. Methods. The patient was treated with 66 MeV fast neutrons to a dose of 20.4 Gy in 13 fractions over 35 days. Results. CT assessments indicate gradually increasing calcification and noticeable reduction of soft-tissue disease in the frontalmore » sinus, orbit and maxillary antrum.There has been some recontouring of the facial structures.The boy conducts an active life, has no pain, and feels well. He was 17 years old at the last follow-up. Discussion. Fast neutrons have a greater biological effectiveness than conventional photon beams. Their use has been associated with improved chance for local control of unresectable disease.This case illustrates their effectiveness in controlling an unusual and aggressive osteogenic sarcoma of the facial bone and sinuses.« less

  6. Demonstration of scan path optimization in proton therapy

    SciTech Connect (OSTI)

    Kang, Joanne H.; Wilkens, Jan J.; Oelfke, Uwe

    2007-09-15

    A three-dimensional (3D) intensity modulated proton therapy treatment plan to be delivered by magnetic scanning may comprise thousands of discrete beam positions. This research presents the minimization of the total scan path length by application of a fast simulated annealing (FSA) optimization algorithm. Treatment plans for clinical prostate and head and neck cases were sequenced for continuous raster scanning in two ways, and the resulting scan path lengths were compared: (1) A simple back-and-forth, top-to-bottom (zigzag) succession, and (2) an optimized path produced as a solution of the FSA algorithm. Using a first approximation of the scanning dynamics, the delivery times for the scan sequences before and after path optimization were calculated for comparison. In these clinical examples, the FSA optimization shortened the total scan path length for the 3D target volumes by approximately 13%-56%. The number of extraneous spilled particles was correspondingly reduced by about 13%-54% due to the more efficient scanning maps that eliminated multiple crossings through regions of zero fluence. The relative decrease in delivery time due to path length minimization was estimated to be less than 1%, due to both a high scanning speed and time requirements that could not be altered by optimization (e.g., time required to change the beam energy). In a preliminary consideration of application to rescanning techniques, the decrease in delivery time was estimated to be 4%-20%.

  7. Applicator-guided volumetric-modulated arc therapy for low-risk endometrial

    Office of Scientific and Technical Information (OSTI)

    cancer (Journal Article) | SciTech Connect Applicator-guided volumetric-modulated arc therapy for low-risk endometrial cancer Citation Details In-Document Search Title: Applicator-guided volumetric-modulated arc therapy for low-risk endometrial cancer The aim of this study was to report the feasibility of volumetric-modulated arc therapy (VMAT) in the postoperative irradiation of the vaginal vault. Moreover, the VMAT technique was compared with 3D conformal radiotherapy (3D-CRT) and

  8. MO-H-19A-02: Investigation of Modulated Electron Arc (MeArc) Therapy for the Treatment of Scalp Tumors

    SciTech Connect (OSTI)

    Eldib, A; Jin, L; Martin, J; Li, J; Chibani, O; Galloway, T; Ma, C

    2014-06-15

    Purpose: Electron arc therapy has long been proposed as the most suitable technique for the treatment of superficial tumors that follow circularly curved surfaces. However it was challenged by unsuitability of the conventional applicators and the lack of adequate 3-D dose calculation tools for arc electron beams in the treatment planning systems (TPS). Now with the availability of an electron specific multi-leaf collimator (eMLC) and an in-house Monte Carlo (MC) based TPS, we were motivated to investigate more advanced modulated electron arc (MeARC) therapy and its beneficial outcome. Methods: We initiated the study by a film measurement conducted in a head and neck phantom, where we delivered electron arcs in a step and shoot manner using the light field as a guide to avoid fields abutments. This step was done to insure enough clearance for the arcs with eMLC. MCBEAM and MCPLAN MC codes were used for the treatment head simulation and phantom dose calculation, respectively. Treatment plans were generated for targets drawn in real patient CTs and head and neck phantom. We utilized beams eye view available from a commercial planning system to create beamlets having same isocenter and adjoined at the scalp surface. Then dose-deposition coefficients from those beamlets were calculated for all electron energies using MCPLAN. An in-house optimization code was then used to find the optimum weights needed from individual beamlets. Results: MeARC showed a nicely tailored dose distribution around the circular curved target on the scalp. Some hot spots were noticed and could be attributed to fields abutment problem owing to the bulging nature of electron profiles. Brain dose was shown to be at lower levels compared to photon treatment. Conclusion: MeARC was shown to be a promising modality for treating scalp cases and could be beneficial to all superficial tumors with a circular curvature.

  9. Sustainable development: Background an represent policy views for governmental agencies, industry, and other specialty groups

    SciTech Connect (OSTI)

    Dickerman, J.A.; Silverman, G.S.

    1995-12-01

    Sustainable development is a phrase that has come into common usage without benefit of clear definition or meaning. Usage very much reflects individual and group perspectives: foresters might consider sustainability in terms of maintaining ecological integrity as part of managing forests for wood harvesting, industry might emphasize pollution control, while government agencies may be looking for new ways to exploit resources on a more continuous basis. Perhaps the greatest commonality among groups considering these issues is that {open_quotes}sustainability{close_quotes} has not been attained but that it needs to occur. The National Association of Environmental Professionals (NAEP) agrees that it is critical to the health of the planet that sustainable development be actively pursued and implemented in international, national, regional, and local policies and practices. To contribute to this effort a {open_quotes}white paper{close_quotes} is being prepared. Its purpose is twofold: (1) to review the existing information from the NAEP Sustainable Development Working Group and the literature and through examination of these policies, to clarify the thinking, what is being done, and what is still needed; and (2) to develop a position and action plan. This action plan should direct NAEP`s actions in making a significant contribution to the national dialog. This paper presents the background and results of the review phase of this white paper development. Representative views on sustainable development policy and practice are presented from three perspectives: governmental agencies, industry, and other specialty groups.

  10. A Pan-STARRS1 VIEW OF THE BIFURCATED SAGITTARIUS STREAM

    SciTech Connect (OSTI)

    Slater, C. T.; Bell, E. F.; Schlafly, E. F.; Juric, M.; Finkbeiner, D. P.; Martin, N. F.; Rix, H.-W.; Goldman, B.; Morganson, E. P.; Bernard, E. J.; Burgett, W. S.; Chambers, K. C.; Kaiser, N.; Magnier, E. A.; Tonry, J. L.; Price, P. A.

    2013-01-01

    We use data from the Pan-STARRS1 survey to present a panoramic view of the Sagittarius tidal stream in the southern Galactic hemisphere. As a result of the extensive sky coverage of Pan-STARRS1, the southern stream is visible along more than 60 Degree-Sign of its orbit, nearly double the length seen by the Sloan Digital Sky Survey. The recently discovered southern bifurcation of the stream is also apparent, with the fainter branch of the stream visible over at least 30 Degree-Sign . Using a combination of fitting both the main-sequence turnoff and the red clump, we measure the distance to both arms of the stream in the south. We find that the distances to the bright arm of the stream agree very well with the N-body models of Law and Majewski. We also find that the faint arm lies {approx}5 kpc closer to the Sun than the bright arm, similar to the behavior seen in the northern hemisphere.

  11. LabVIEW-based control software for para-hydrogen induced polarization instrumentation

    SciTech Connect (OSTI)

    Agraz, Jose Grunfeld, Alexander; Li, Debiao; BIRI, Cedars Sinai Medical Center, West Hollywood, California 90048 ; Cunningham, Karl; Willey, Cindy; Pozos, Robert; Wagner, Shawn

    2014-04-15

    The elucidation of cell metabolic mechanisms is the modern underpinning of the diagnosis, treatment, and in some cases the prevention of disease. Para-Hydrogen induced polarization (PHIP) enhances magnetic resonance imaging (MRI) signals over 10 000 fold, allowing for the MRI of cell metabolic mechanisms. This signal enhancement is the result of hyperpolarizing endogenous substances used as contrast agents during imaging. PHIP instrumentation hyperpolarizes Carbon-13 ({sup 13}C) based substances using a process requiring control of a number of factors: chemical reaction timing, gas flow, monitoring of a static magnetic field (B{sub o}), radio frequency (RF) irradiation timing, reaction temperature, and gas pressures. Current PHIP instruments manually control the hyperpolarization process resulting in the lack of the precise control of factors listed above, resulting in non-reproducible results. We discuss the design and implementation of a LabVIEW based computer program that automatically and precisely controls the delivery and manipulation of gases and samples, monitoring gas pressures, environmental temperature, and RF sample irradiation. We show that the automated control over the hyperpolarization process results in the hyperpolarization of hydroxyethylpropionate. The implementation of this software provides the fast prototyping of PHIP instrumentation for the evaluation of a myriad of {sup 13}C based endogenous contrast agents used in molecular imaging.

  12. Quantifying and Mapping the Digital Divide from an Internet Point of View

    SciTech Connect (OSTI)

    Cottrell, R.Les; Khan, Shahryar; Williams, Jerrod; Mehdi, Akbar; Kalim, Umar; Ali, Arshad; /NUST, Rawalpindi

    2008-09-18

    Quantitative knowledge of the magnitude, extent and trends of the Digital Divide are critical to understand and identify the regions most in need of help, to make rational decisions on how to address the problems and to make cases for executives, funding agencies and politicians. We report on a project (PingER) to measure the Digital Divide from the point of view of Internet performance. The PingER project has been measuring Internet performance since 1995 and with the increased emphasis on measuring and tracking the Digital Divide, it now covers over 700 hosts in over 150 countries that between them contain over 99% of the world's Internet connected population. In this paper we will describe the how PingER works, it deployment, the data analysis, and presentation. We also introduce a new PingER visualization tool (ViPER) that provides a more appealing interactive visualization of the PingER data and also works on mobile PDAs. We will also show results from PingER that illustrate the magnitude, extent and trends for the Digital Divide, and also compare PingER results with some human development and technology indices.

  13. Applicator-guided volumetric-modulated arc therapy for low-risk...

    Office of Scientific and Technical Information (OSTI)

    low-risk endometrial cancer Citation Details In-Document Search Title: Applicator-guided volumetric-modulated arc therapy for low-risk endometrial cancer The aim of this study ...

  14. Automatic CT simulation optimization for radiation therapy: A general strategy

    SciTech Connect (OSTI)

    Li, Hua Chen, Hsin-Chen; Tan, Jun; Gay, Hiram; Michalski, Jeff M.; Mutic, Sasa; Yu, Lifeng; Anastasio, Mark A.; Low, Daniel A.

    2014-03-15

    Purpose: In radiation therapy, x-ray computed tomography (CT) simulation protocol specifications should be driven by the treatment planning requirements in lieu of duplicating diagnostic CT screening protocols. The purpose of this study was to develop a general strategy that allows for automatically, prospectively, and objectively determining the optimal patient-specific CT simulation protocols based on radiation-therapy goals, namely, maintenance of contouring quality and integrity while minimizing patient CT simulation dose. Methods: The authors proposed a general prediction strategy that provides automatic optimal CT simulation protocol selection as a function of patient size and treatment planning task. The optimal protocol is the one that delivers the minimum dose required to provide a CT simulation scan that yields accurate contours. Accurate treatment plans depend on accurate contours in order to conform the dose to actual tumor and normal organ positions. An image quality index, defined to characterize how simulation scan quality affects contour delineation, was developed and used to benchmark the contouring accuracy and treatment plan quality within the predication strategy. A clinical workflow was developed to select the optimal CT simulation protocols incorporating patient size, target delineation, and radiation dose efficiency. An experimental study using an anthropomorphic pelvis phantom with added-bolus layers was used to demonstrate how the proposed prediction strategy could be implemented and how the optimal CT simulation protocols could be selected for prostate cancer patients based on patient size and treatment planning task. Clinical IMRT prostate treatment plans for seven CT scans with varied image quality indices were separately optimized and compared to verify the trace of target and organ dosimetry coverage. Results: Based on the phantom study, the optimal image quality index for accurate manual prostate contouring was 4.4. The optimal tube potentials for patient sizes of 38, 43, 48, 53, and 58 cm were 120, 140, 140, 140, and 140 kVp, respectively, and the corresponding minimum CTDIvol for achieving the optimal image quality index 4.4 were 9.8, 32.2, 100.9, 241.4, and 274.1 mGy, respectively. For patients with lateral sizes of 43–58 cm, 120-kVp scan protocols yielded up to 165% greater radiation dose relative to 140-kVp protocols, and 140-kVp protocols always yielded a greater image quality index compared to the same dose-level 120-kVp protocols. The trace of target and organ dosimetry coverage and the γ passing rates of seven IMRT dose distribution pairs indicated the feasibility of the proposed image quality index for the predication strategy. Conclusions: A general strategy to predict the optimal CT simulation protocols in a flexible and quantitative way was developed that takes into account patient size, treatment planning task, and radiation dose. The experimental study indicated that the optimal CT simulation protocol and the corresponding radiation dose varied significantly for different patient sizes, contouring accuracy, and radiation treatment planning tasks.

  15. Intensity Modulated Radiation Therapy With Dose Painting to Treat Rhabdomyosarcoma

    SciTech Connect (OSTI)

    Yang, Joanna C.; Dharmarajan, Kavita V.; Wexler, Leonard H.; La Quaglia, Michael P.; Happersett, Laura; Wolden, Suzanne L.

    2012-11-01

    Purpose: To examine local control and patterns of failure in rhabdomyosarcoma patients treated with intensity modulated radiation therapy (RT) with dose painting (DP-IMRT). Patients and Methods: A total of 41 patients underwent DP-IMRT with chemotherapy for definitive treatment. Nineteen also underwent surgery with or without intraoperative RT. Fifty-six percent had alveolar histologic features. The median interval from beginning chemotherapy to RT was 17 weeks (range, 4-25). Very young children who underwent second-look procedures with or without intraoperative RT received reduced doses of 24-36 Gy in 1.4-1.8-Gy fractions. Young adults received 50.4 Gy to the primary tumor and lower doses of 36 Gy in 1.8-Gy fractions to at-risk lymph node chains. Results: With 22 months of median follow-up, the actuarial local control rate was 90%. Patients aged {<=}7 years who received reduced overall and fractional doses had 100% local control, and young adults had 79% (P=.07) local control. Three local failures were identified in young adults whose primary target volumes had received 50.4 Gy in 1.8-Gy fractions. Conclusions: DP-IMRT with lower fractional and cumulative doses is feasible for very young children after second-look procedures with or without intraoperative RT. DP-IMRT is also feasible in adolescents and young adults with aggressive disease who would benefit from prophylactic RT to high-risk lymph node chains, although dose escalation might be warranted for improved local control. With limited follow-up, it appears that DP-IMRT produces local control rates comparable to those of sequential IMRT in patients with rhabdomyosarcoma.

  16. Heuristic optimization of the scanning path of particle therapy beams

    SciTech Connect (OSTI)

    Pardo, J.; Donetti, M.; Bourhaleb, F.; Ansarinejad, A.; Attili, A.; Cirio, R.; Garella, M. A.; Giordanengo, S.; Givehchi, N.; La Rosa, A.; Marchetto, F.; Monaco, V.; Pecka, A.; Peroni, C.; Russo, G.; Sacchi, R.

    2009-06-15

    Quasidiscrete scanning is a delivery strategy for proton and ion beam therapy in which the beam is turned off when a slice is finished and a new energy must be set but not during the scanning between consecutive spots. Different scanning paths lead to different dose distributions due to the contribution of the unintended transit dose between spots. In this work an algorithm to optimize the scanning path for quasidiscrete scanned beams is presented. The classical simulated annealing algorithm is used. It is a heuristic algorithm frequently used in combinatorial optimization problems, which allows us to obtain nearly optimal solutions in acceptable running times. A study focused on the best choice of operational parameters on which the algorithm performance depends is presented. The convergence properties of the algorithm have been further improved by using the next-neighbor algorithm to generate the starting paths. Scanning paths for two clinical treatments have been optimized. The optimized paths are found to be shorter than the back-and-forth, top-to-bottom (zigzag) paths generally provided by the treatment planning systems. The gamma method has been applied to quantify the improvement achieved on the dose distribution. Results show a reduction of the transit dose when the optimized paths are used. The benefit is clear especially when the fluence per spot is low, as in the case of repainting. The minimization of the transit dose can potentially allow the use of higher beam intensities, thus decreasing the treatment time. The algorithm implemented for this work can optimize efficiently the scanning path of quasidiscrete scanned particle beams. Optimized scanning paths decrease the transit dose and lead to better dose distributions.

  17. MCNP speed advances for boron neutron capture therapy

    SciTech Connect (OSTI)

    Goorley, J.T.; McKinney, G.; Adams, K.; Estes, G.

    1998-04-01

    The Boron Neutron Capture Therapy (BNCT) treatment planning process of the Beth Israel Deaconess Medical Center-M.I.T team relies on MCNP to determine dose rates in the subject`s head for various beam orientations. In this time consuming computational process, four or five potential beams are investigated. Of these, one or two final beams are selected and thoroughly evaluated. Recent advances greatly decreased the time needed to do these MCNP calculations. Two modifications to the new MCNP4B source code, lattice tally and tracking enhancements, reduced the wall-clock run times of a typical one million source neutrons run to one hour twenty five minutes on a 200 MHz Pentium Pro computer running Linux and using the GNU FORTRAN compiler. Previously these jobs used a special version of MCNP4AB created by Everett Redmond, which completed in two hours two minutes. In addition to this 30% speedup, the MCNP4B version was adapted for use with Parallel Virtual Machine (PVM) on personal computers running the Linux operating system. MCNP, using PVM, can be run on multiple computers simultaneously, offering a factor of speedup roughly the same as the number of computers used. With two 200 MHz Pentium Pro machines, the run time was reduced to forty five minutes, a 1.9 factor of improvement over the single Linux computer. While the time of a single run was greatly reduced, the advantages associated with PVM derive from using computational power not already used. Four possible beams, currently requiring four separate runs, could be run faster when each is individually run on a single machine under Windows NT, rather than using Linux and PVM to run one after another with each multiprocessed across four computers. It would be advantageous, however, to use PVM to distribute the final two beam orientations over four computers.

  18. Shape memory polymer foams for endovascular therapies (Patent) | SciTech

    Office of Scientific and Technical Information (OSTI)

    Connect Patent: Shape memory polymer foams for endovascular therapies Citation Details In-Document Search Title: Shape memory polymer foams for endovascular therapies A system for occluding a physical anomaly. One embodiment comprises a shape memory material body wherein the shape memory material body fits within the physical anomaly occluding the physical anomaly. The shape memory material body has a primary shape for occluding the physical anomaly and a secondary shape for being positioned

  19. Decision Regret in Men Undergoing Dose-Escalated Radiation Therapy for Prostate Cancer

    SciTech Connect (OSTI)

    Steer, Anna N.; Aherne, Noel J.; Gorzynska, Karen; Hoffman, Matthew; Last, Andrew; Hill, Jacques; Shakespeare, Thomas P.; Rural Clinical School Faculty of Medicine, University of New South Wales, Coffs Harbour

    2013-07-15

    Purpose: Decision regret (DR) is a negative emotion associated with medical treatment decisions, and it is an important patient-centered outcome after therapy for localized prostate cancer. DR has been found to occur in up to 53% of patients treated for localized prostate cancer, and it may vary depending on treatment modality. DR after modern dose-escalated radiation therapy (DE-RT) has not been investigated previously, to our knowledge. Our primary aim was to evaluate DR in a cohort of patients treated with DE-RT. Methods and Materials: We surveyed 257 consecutive patients with localized prostate cancer who had previously received DE-RT, by means of a validated questionnaire. Results: There were 220 responses (85.6% response rate). Image-guided intensity modulated radiation therapy was given in 85.0% of patients and 3-dimensional conformal radiation therapy in 15.0%. Doses received included 73.8 Gy (34.5% patients), 74 Gy (53.6%), and 76 Gy (10.9%). Neoadjuvant androgen deprivation (AD) was given in 51.8% of patients and both neoadjuvant and adjuvant AD in 34.5%. The median follow-up time was 23 months (range, 12-67 months). In all, 3.8% of patients expressed DR for their choice of treatment. When asked whether they would choose DE-RT or AD again, only 0.5% probably or definitely would not choose DE-RT again, compared with 8.4% for AD (P<.01). Conclusion: Few patients treated with modern DE-RT express DR, with regret appearing to be lower than in previously published reports of patients treated with radical prostatectomy or older radiation therapy techniques. Patients experienced more regret with the AD component of treatment than with the radiation therapy component, with implications for informed consent. Further research should investigate regret associated with individual components of modern therapy, including AD, radiation therapy and surgery.

  20. Cherenkov Video Imaging Allows for the First Visualization of Radiation Therapy in Real Time

    SciTech Connect (OSTI)

    Jarvis, Lesley A.; Zhang, Rongxiao; Gladstone, David J.; Jiang, Shudong; Hitchcock, Whitney; Friedman, Oscar D.; Glaser, Adam K.; Jermyn, Michael; Pogue, Brian W.

    2014-07-01

    Purpose: To determine whether Cherenkov light imaging can visualize radiation therapy in real time during breast radiation therapy. Methods and Materials: An intensified charge-coupled device (CCD) camera was synchronized to the 3.25-μs radiation pulses of the clinical linear accelerator with the intensifier set × 100. Cherenkov images were acquired continuously (2.8 frames/s) during fractionated whole breast irradiation with each frame an accumulation of 100 radiation pulses (approximately 5 monitor units). Results: The first patient images ever created are used to illustrate that Cherenkov emission can be visualized as a video during conditions typical for breast radiation therapy, even with complex treatment plans, mixed energies, and modulated treatment fields. Images were generated correlating to the superficial dose received by the patient and potentially the location of the resulting skin reactions. Major blood vessels are visible in the image, providing the potential to use these as biological landmarks for improved geometric accuracy. The potential for this system to detect radiation therapy misadministrations, which can result from hardware malfunction or patient positioning setup errors during individual fractions, is shown. Conclusions: Cherenkoscopy is a unique method for visualizing surface dose resulting in real-time quality control. We propose that this system could detect radiation therapy errors in everyday clinical practice at a time when these errors can be corrected to result in improved safety and quality of radiation therapy.