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Sample records for interstitial therapy view

  1. Displacement Correction Scheme for MR-Guided Interstitial Laser Therapy

    E-Print Network [OSTI]

    van Vliet, Lucas J.

    Displacement Correction Scheme for MR-Guided Interstitial Laser Therapy S. Suprijanto1 , M.W. Vogel[1,3]. In the absence of motion, MR thermometry based on phase imaging is quite accurate[12 , F.M. Vos1 , H.A. Vrooman2,3 , and A.M. Vossepoel1 1 Pattern Recognition Group, Department

  2. Most Viewed Documents for Biology and Medicine: December 2014...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Most Viewed Documents for Biology and Medicine: December 2014 Dose and volume specification for reporting interstitial therapy NONE (1997) 38 Modification to the Monte Carlo...

  3. Image-guided therapy system for interstitial gynecologic brachytherapy in a multimodality operating suite

    E-Print Network [OSTI]

    Egger, Jan

    2013-01-01

    In this contribution, an image-guided therapy system supporting gynecologic radiation therapy is introduced. The overall workflow of the presented system starts with the arrival of the patient and ends with follow-up examinations by imaging and a superimposed visualization of the modeled device from a PACS system. Thereby, the system covers all treatments stages (pre-, intra- and postoperative) and has been designed and constructed by a computer scientist with feedback from an interdisciplinary team of physicians and engineers. This integrated medical system enables dispatch of diagnostic images directly after acquisition to a processing workstation that has an on-board 3D Computer Aided Design model of a medical device. Thus, allowing precise identification of catheter location in the 3D imaging model which later provides rapid feedback to the clinician regarding device location. Moreover, the system enables the ability to perform patient-specific pre-implant evaluation by assessing the placement of intersti...

  4. Synchrotron Radiation Therapy from a Medical Physics point of view

    SciTech Connect (OSTI)

    Prezado, Y.; Berkvens, P.; Braeuer-Krisch, E.; Renier, M.; Bravin, A. [ID17 Biomedical Beamline, European Synchrotron Radiation Facility (ESRF), 6 Rue Jules Horowitz B.P. 220, 38043 Grenoble Cedex (France); Adam, J. F. [INSERM, U836, Equipe 6, BP 170, Grenoble Cedex 9, F-38042 (France); Universite Joseph Fourier, B.P. 51, Grenoble Cedex 9, F-38041 (France); ID17 Biomedical Beamline, European Synchrotron Radiation Facility (ESRF), 6 Rue Jules Horowitz B.P. 220, 38043 Grenoble Cedex (France); Centre Hospitalier Universitaire, B.P. 217, Grenoble Cedex 9, F-38043 (France); Martinez-Rovira, I. [ID17 Biomedical Beamline, European Synchrotron Radiation Facility (ESRF), 6 Rue Jules Horowitz B.P. 220, 38043 Grenoble Cedex (France); Institut de Tecniques Energetiques, Universitat Politecnica de Catalunya, Diagonal 647, E-08028 Barcelona (Spain); Fois, G. [ID17 Biomedical Beamline, European Synchrotron Radiation Facility (ESRF), 6 Rue Jules Horowitz B.P. 220, 38043 Grenoble Cedex (France); Dipartimento di Fisica, Universita degli Studi di Cagliari, Strada Provinciale Monserrato Sestu km 0.700, Monserrato, Cagliari 09042 (Italy); Thengumpallil, S. [ID17 Biomedical Beamline, European Synchrotron Radiation Facility (ESRF), 6 Rue Jules Horowitz B.P. 220, 38043 Grenoble Cedex (France); Dipartimento di Fisica E. Amaldi, Universita degli Studi Roma Tre, 84 Via della Vasca Navale, 00146 Roma (Italy); Edouard, M.; Deman, P. [INSERM, U836, Equipe 6, BP 170, Grenoble Cedex 9, F-38042 (France); Universite Joseph Fourier, B.P. 51, Grenoble Cedex 9, F-38041 (France); ID17 Biomedical Beamline, European Synchrotron Radiation Facility (ESRF), 6 Rue Jules Horowitz B.P. 220, 38043 Grenoble Cedex (France); Vautrin, M. [INSERM, U836, Equipe 6, BP 170, Grenoble Cedex 9, F-38042 (France); Universite Joseph Fourier, B.P. 51, Grenoble Cedex 9, F-38041 (France); DOSIsoft, Cachan (France)

    2010-07-23

    Synchrotron radiation (SR) therapy is a promising alternative to treat brain tumors, whose management is limited due to the high morbidity of the surrounding healthy tissues. Several approaches are being explored by using SR at the European Synchrotron Radiation Facility (ESRF), where three techniques are under development Synchrotron Stereotactic Radiation Therapy (SSRT), Microbeam Radiation Therapy (MRT) and Minibeam Radiation Therapy (MBRT).The sucess of the preclinical studies on SSRT and MRT has paved the way to clinical trials currently in preparation at the ESRF. With this aim, different dosimetric aspects from both theoretical and experimental points of view have been assessed. In particular, the definition of safe irradiation protocols, the beam energy providing the best balance between tumor treatment and healthy tissue sparing in MRT and MBRT, the special dosimetric considerations for small field dosimetry, etc will be described. In addition, for the clinical trials, the definition of appropiate dosimetry protocols for patients according to the well established European Medical Physics recommendations will be discussed. Finally, the state of the art of the MBRT technical developments at the ESRF will be presented. In 2006 A. Dilmanian and collaborators proposed the use of thicker microbeams (0.36-0.68 mm). This new type of radiotherapy is the most recently implemented technique at the ESRF and it has been called MBRT. The main advantage of MBRT with respect to MRT is that it does not require high dose rates. Therefore it can be more easily applied and extended outside synchrotron sources in the future.

  5. Ulcerative colitis and steroid-responsive, diffuse interstitial lung disease

    SciTech Connect (OSTI)

    Balestra, D.J.; Balestra, S.T.; Wasson, J.H.

    1988-07-01

    The authors describe a patient with ulcerative colitis and extracolonic manifestations in whom diffuse interstitial pulmonary disease developed that was responsive to glucocorticoid therapy one year after total proctocolectomy. The patient presented in December 1983 with a subacute course marked by cough and progressive exertional dyspnea, abnormal chest examination results, and a chest roentgenogram that revealed diffuse interstitital and alveolar infiltrates. A transbronchial biopsy specimen revealed a polymorphic interstitial infiltrate, mild interstitial fibrosis without apparent intraluminal fibrosis, and no vasculitis, granulomas, or significant eosinophilic infiltration. Within one week of the initiation of daily high-dose steroid therapy, the patient's symptoms dramatically improved; chest roentgenogram and forced vital capacity (60%) improved at a slower rate. All three measures deteriorated when alternate-day prednisone therapy was started but once again improved until the patient was totally asymptomatic, chest roentgenograms were normal, and forced vital capacity was 80% of the predicted value 2 1/2 years later.

  6. Fractionalization of Interstitials in Curved Colloidal Crystals

    E-Print Network [OSTI]

    William T. M. Irvine; Mark J. Bowick; Paul M. Chaikin

    2013-10-11

    Understanding the out-of equilibrium behaviour of point defects in crystals, yields insights into the nature and fragility of the ordered state, as well as being of great practical importance. In some rare cases defects are spontaneously healed - a one-dimensional crystal formed by a line of identical charged particles, for example, can accommodate an interstitial (extra particle) by a re-adjusting all particle positions to even out the spacing. In sharp contrast, particles organized into a perfect hexagonal crystal in the plane cannot accommodate an interstitial by a simple re-adjustment of the particle spacing - the interstitial remains instead trapped between lattice sites and diffuses by hopping, leaving the crystal permanently defected. Here we report on the behavior of interstitials in colloidal crystals on curved surfaces. Using optical tweezers operated independently of three dimensional imaging, we insert a colloidal interstitial in a lattice of similar particles on flat and curved (positively and negatively) oil-glycerol interfaces and image the ensuing dynamics. We find that, unlike in flat space, the curved crystals self-heal through a collective rearrangement that re-distributes the increased density associated with the interstitial. The self-healing process can be interpreted in terms of an out of equilibrium interaction of topological defects with each other and with the underlying curvature. Our observations suggest the existence of "particle fractionalization" on curved surface crystals.

  7. Di-interstitial defect in silicon revisited

    SciTech Connect (OSTI)

    Londos, C. A.; Antonaras, G.; Chroneos, A.; Department of Materials, Imperial College London, London SW7 2BP

    2013-11-21

    Infrared spectroscopy was used to study the defect spectrum of Cz-Si samples following fast neutron irradiation. We mainly focus on the band at 533 cm{sup ?1}, which disappears from the spectra at ?170 °C, exhibiting similar thermal stability with the Si-P6 electron paramagnetic resonance (EPR) spectrum previously correlated with the di-interstitial defect. The suggested structural model of this defect comprises of two self-interstitial atoms located symmetrically around a lattice site Si atom. The band anneals out following a first-order kinetics with an activation energy of 0.88 ± 0.3 eV. This value does not deviate considerably from previously quoted experimental and theoretical values for the di-interstitial defect. The present results indicate that the 533 cm{sup ?1} IR band originates from the same structure as that of the Si-P6 EPR spectrum.

  8. Friedel-Like Oscillations from Interstitial Iron in Superconducting...

    Office of Scientific and Technical Information (OSTI)

    Interstitial Iron in Superconducting Fe1+yTe0.62Se0.38 Using polarized and unpolarized neutron scattering we show that interstitial Fe in superconducting Fe1+yTe1-xSex...

  9. Identification of Early Interstitial Lung Disease in Smokers from the

    E-Print Network [OSTI]

    Identification of Early Interstitial Lung Disease in Smokers from the COPDGene Study George R interstitial lung disease (ILD) on chest computed tomographic (CT) scans. Materials and Methods: The CT scans: Early interstitial lung disease; CT scan; smoker. ªAUR, 2010 I diopathic pulmonary fibrosis (IPF

  10. Interstitial diffusion of ion-implanted boron in crystalline silicon

    E-Print Network [OSTI]

    O. I. Velichko; A. P. Kavaliova

    2012-07-03

    Modeling of the long-range migration of boron interstitials during low temperature annealing of ion-implanted silicon crystals has been carried out.

  11. Bistability of Cation Interstitials in II-VI Semiconductors

    SciTech Connect (OSTI)

    Wei, S. H.; Dalpian, G. M.

    2005-11-01

    The stability of cation interstitials in II-VI semiconductors is studied using ab initio methods. We find that interstitials in the neutral charge state are more stable in the tetrahedral interstitial site near the cation, whereas in the (2+) charge state, they are more stable near the anion. The diffusion energy barrier changes when the defect charge state changes. Therefore, if electrons/holes are taken from the defect level by light, changing its charge state, the interstitial atom will be able to diffuse almost spontaneously due to a reduced diffusion barrier.

  12. Interstitial Fe in MgO

    SciTech Connect (OSTI)

    Mølholt, T. E., E-mail: tem4@hi.is; Gislason, H. P.; Ólafsson, S. [Science Institute, University of Iceland, Dunhaga 3, IS-107 Reykjavík (Iceland); Mantovan, R. [Laboratorio MDM, IMM-CNR, Via Olivetti 2, 20846 Agrate Brianza (MB) (Italy); Gunnlaugsson, H. P.; Svane, A.; Weyer, G. [Department of Physics and Astronomy, Aarhus University, DK-8000 Aarhus C (Denmark); Masenda, H.; Naidoo, D. [School of Physics, University of the Witwatersrand, WITS 2050 (South Africa); Bharuth-Ram, K. [Durban University of Technology, Durban 4001 (South Africa); Fanciulli, M. [Laboratorio MDM, IMM-CNR, Via Olivetti 2, 20846 Agrate Brianza (MB) (Italy); Dipartimento di Scienza dei Materiali, Università di Milano Bicocca, Milano (Italy); Johnston, K. [PH Department, ISOLDE/CERN, 1211 Geneva 23 (Switzerland); Langouche, G. [Instituut voor Kern-en Stralings fysika, University of Leuven, B-3001 Leuven (Belgium); Sielemann, R. [Helmholtz-Zentrum-Berlin für Materialien und Energie, D-14109 Berlin (Germany)

    2014-01-14

    Isolated {sup 57}Fe atoms were studied in MgO single-crystals by emission Mössbauer spectroscopy following implantation of {sup 57}Mn decaying to {sup 57}Fe. Four Mössbauer spectral components were found corresponding to different Fe lattice positions and/or charge states. Two components represent Fe atoms substituting Mg as Fe{sup 2+} and Fe{sup 3+}, respectively; a third component is due to Fe in a strongly implantation-induced disturbed region. The fourth component, which is the focus of this paper, can be assigned to Fe at an interstitial site. Comparison of its measured isomer shift with ab initio calculations suggests that the interstitial Fe is located on, or close to, the face of the rock-salt MgO structure. To harmonize such an assignment with the measured near-zero quadrupole interaction a local motion process (cage motion) of the Fe has to be stipulated. The relation of such a local motion as a starting point for long range diffusion is discussed.

  13. Original article Lentivirus-induced interstitial lung disease

    E-Print Network [OSTI]

    Boyer, Edmond

    Original article Lentivirus-induced interstitial lung disease: pulmonary pathology in sheep a chronic disease in sheep affecting, among other organs, the lungs. Interstitial pneumonitis is similar the pathological features of lungs of sheep naturally infected with visna-maedi virus with the results obtained

  14. Interstitial rotating shield brachytherapy for prostate cancer

    SciTech Connect (OSTI)

    Adams, Quentin E., E-mail: quentin-adams@uiowa.edu; Xu, Jinghzu; Breitbach, Elizabeth K.; Li, Xing; Rockey, William R.; Kim, Yusung; Wu, Xiaodong; Flynn, Ryan T. [Department of Radiation Oncology, University of Iowa, 200 Hawkins Drive, Iowa City, Iowa 52242 (United States)] [Department of Radiation Oncology, University of Iowa, 200 Hawkins Drive, Iowa City, Iowa 52242 (United States); Enger, Shirin A. [Medical Physics Unit, McGill University, 1650 Cedar Ave, Montreal, Quebec H3G 1A4 (Canada)] [Medical Physics Unit, McGill University, 1650 Cedar Ave, Montreal, Quebec H3G 1A4 (Canada)

    2014-05-15

    Purpose: To present a novel needle, catheter, and radiation source system for interstitial rotating shield brachytherapy (I-RSBT) of the prostate. I-RSBT is a promising technique for reducing urethra, rectum, and bladder dose relative to conventional interstitial high-dose-rate brachytherapy (HDR-BT). Methods: A wire-mounted 62 GBq{sup 153}Gd source is proposed with an encapsulated diameter of 0.59 mm, active diameter of 0.44 mm, and active length of 10 mm. A concept model I-RSBT needle/catheter pair was constructed using concentric 50 and 75 ?m thick nickel-titanium alloy (nitinol) tubes. The needle is 16-gauge (1.651 mm) in outer diameter and the catheter contains a 535 ?m thick platinum shield. I-RSBT and conventional HDR-BT treatment plans for a prostate cancer patient were generated based on Monte Carlo dose calculations. In order to minimize urethral dose, urethral dose gradient volumes within 0–5 mm of the urethra surface were allowed to receive doses less than the prescribed dose of 100%. Results: The platinum shield reduced the dose rate on the shielded side of the source at 1 cm off-axis to 6.4% of the dose rate on the unshielded side. For the case considered, for the same minimum dose to the hottest 98% of the clinical target volume (D{sub 98%}), I-RSBT reduced urethral D{sub 0.1cc} below that of conventional HDR-BT by 29%, 33%, 38%, and 44% for urethral dose gradient volumes within 0, 1, 3, and 5 mm of the urethra surface, respectively. Percentages are expressed relative to the prescription dose of 100%. For the case considered, for the same urethral dose gradient volumes, rectum D{sub 1cc} was reduced by 7%, 6%, 6%, and 6%, respectively, and bladder D{sub 1cc} was reduced by 4%, 5%, 5%, and 6%, respectively. Treatment time to deliver 20 Gy with I-RSBT was 154 min with ten 62 GBq {sup 153}Gd sources. Conclusions: For the case considered, the proposed{sup 153}Gd-based I-RSBT system has the potential to lower the urethral dose relative to HDR-BT by 29%–44% if the clinician allows a urethral dose gradient volume of 0–5 mm around the urethra to receive a dose below the prescription. A multisource approach is necessary in order to deliver the proposed {sup 153}Gd-based I-RSBT technique in reasonable treatment times.

  15. Complexes of self-interstitials with oxygen atoms in Ge

    SciTech Connect (OSTI)

    Khirunenko, L. I.; Pomozov, Yu. V.; Sosnin, M. G.; Abrosimov, N. V.; Riemann, H.

    2014-02-21

    Interactions of germanium self-interstitials with interstitial oxygen atoms in Ge subjected to irradiation at ?80 K and subsequently to annealing have been studied. To distinguish the processes involving vacancies and self-interstitials the doping with tin was used. It was shown that absorption lines with maximum at 602, 674, 713 and 803 cm{sup ?1} are self-interstitials-related. Two lines at 602 and 674, which develop upon annealing in the temperature range 180–240 K, belong to IO complexes, while the bands at 713 and 803 cm{sup ?1}, which emerge after annealing at T>220 K, are associated with I{sub 2}O. It is argued that the annealing of IO occurs by two mechanisms: by dissociation and by diffusion.

  16. Effects of interstitial flow on tumor cell migration

    E-Print Network [OSTI]

    Polacheck, William J. (William Joseph)

    2010-01-01

    Interstitial flow is the convective transport of fluid through tissue extracellular matrix. This creeping fluid flow has been shown to affect the morphology and migration of cells such as fibroblasts, cancer cells, endothelial ...

  17. Integration of microvascular, interstitial, and lymphatic function to determine the effect of their interaction on interstitial fluid volume 

    E-Print Network [OSTI]

    Dongaonkar, Ranjeet Manohar

    2009-05-15

    Although the physics of interstitial fluid balance is relatively well understood, clinical options for the treatment of edema, the accumulation of fluid in the interstitium, are limited. Two related reasons for this failure ...

  18. Determination of Interstitial Water Chemistry and Porosity in

    E-Print Network [OSTI]

    Sheffield, University of

    of a petroleum hydrocarbon plume in the U.K. Upper Chalk aquifer as part of a natural attenuation assessment to the composition of the host material (1). Data on interstitial water chemistry are important for correlating hydraulic and gas- pressure squeezing (12-15), centrifugation (1, 3), porous suction samplers (2, 7

  19. Microdefects and self-interstitial diffusion in crystalline silicon

    SciTech Connect (OSTI)

    Knowlton, W.B.

    1998-05-01

    In this thesis, a study is presented of D-defects and self-interstitial diffusion in silicon using Li ion (Li{sup +}) drifting in an electric field and transmission electron microscopy (TEM). Obstruction of Li{sup +} drifting has been found in wafers from certain but not all FZ p-type Si. Incomplete Li{sup +} drifting always occurs in the central region of the wafers. This work established that interstitial oxygen is not responsible for hindering Li{sup +} drifting. TEM was performed on a samples from the partially Li{sup +} drifted area and compared to regions without D-defects. Precipitates were found only in the region containing D-defects that had partially Li{sup +} drifted. This result indicates D-defects are responsible for the precipitation that halts the Li{sup +} drift process. Nitrogen (N) doping has been shown to eliminate D-defects as measured by conventional techniques. Li{sup +} drifting and D-defects provide a useful means to study Si self-interstitial diffusion. The process modeling program SUPREM-IV was used to simulate the results of Si self-interstitial diffusion obtained from Li{sup +} drifting experiments. Anomalous results from the Si self-interstitial diffusion experiments forced a re-examination of the possibility of thermal dissociation of D-defects. Thermal annealing experiments that were performed support this possibility. A review of the current literature illustrates the need for more research on the effects of thermal processing on FZ Si to understand the dissolution kinetics of D-defects.

  20. DFT STUDY REVISES INTERSTITIAL CONFIGURATIONS IN HCP Zr

    SciTech Connect (OSTI)

    Samolyuk, German D; Golubov, Stanislav I; Osetskiy, Yury N; Stoller, Roger E

    2012-06-01

    Analysis of experimental result on microstructure evolution in irradiated Zr and alloys has demonstrated that available knowledge on self-interstitial defects in Zr is in contradiction. We therefore have initiated an extensive theoretical and modeling program to clarify this issue. In this report we present first ab initio calculations results of single SIA configurations in Zr. We demonstrate importance of simulations cell size, applied exchange-correlation functional and simulated c/a ratio. The results obtained demonstrate clearly that the most stable configurations are in basal plane and provide some evidences for enhanced interstitial transport along basal planes. The results obtained will be used in generation a new interatomic potential for Zr to be used in large-scale atomistic modeling of mechanisms relevant for radiation-induced microstructure evolution.

  1. Ureteral stent insertion for gynecologic interstitial high-dose-rate brachytherapy

    E-Print Network [OSTI]

    2015-01-01

    gynecologic interstitial brachytherapy. Int J Radiat OncolBrachytherapy Ureteral stent insertion forhigh-dose-rate brachytherapy D. Jeffrey Demanes*, Robyn

  2. Outcomes of High-Dose-Rate Interstitial Brachytherapy in the Treatment of Locally Advanced Cervical Cancer: Long-term Results

    SciTech Connect (OSTI)

    Pinn-Bingham, Melva; Puthawala, Ajmel A.; Syed, A.M. Nisar; Sharma, Anil; DiSaia, Philip; Berman, Michael; Tewari, Krishnansu S.; Randall-Whitis, Leslie; Mahmood, Usama; Ramsinghani, Nilam; Kuo, Jeffrey; Chen, Wen-Pin; McLaren, Christine E.

    2013-03-01

    Purpose: The purpose of this study was to determine locoregional control (LRC), disease-free survival (DFS), and toxicity of high-dose-rate interstitial brachytherapy (HDR-ISBT) in the treatment of locally advanced cervical cancer. Methods and Materials: Between March 1996 and May 2009, 116 patients with cervical cancer were treated. Of these, 106 (91%) patients had advanced disease (International Federation of Gynecology and Obstetrics stage IIB-IVA). Ten patients had stage IB, 48 had stage II, 51 had stage III, and 7 had stage IVA disease. All patients were treated with a combination of external beam radiation therapy (EBRT) to the pelvis (5040 cGy) and 2 applications of HDR-ISBT to a dose of 3600 cGy to the implanted volume. Sixty-one percent of patients also received interstitial hyperthermia, and 94 (81%) patients received chemotherapy. Results: Clinical LRC was achieved in 99 (85.3%) patients. Three-year DFS rates were 59%, 67%, 71%, and 57% for patients with stage IB, II, III, and IVA disease, respectively. The 5-year DFS and overall survival rates for the entire group were 60% and 44%, respectively. Acute and late toxicities were within acceptable limits. Conclusions: Locally advanced cervical cancer patients for whom intracavitary BT is unsuitable can achieve excellent LRC and OS with a combination of EBRT and HDR-ISBT.

  3. 1 Art Therapy ART THERAPY

    E-Print Network [OSTI]

    Vertes, Akos

    1 Art Therapy ART THERAPY Art Therapy Graduate Program trains exceptionally skilled therapists whose professional practice is grounded in a broad understanding of the most current clinical art unique art therapist identity. GRADUATE Master's programs · Master of Arts in the field of art therapy

  4. Automated segmentation of lungs with severe interstitial lung disease in CT

    E-Print Network [OSTI]

    Automated segmentation of lungs with severe interstitial lung disease in CT Jiahui Wang Department: Accurate segmentation of lungs with severe interstitial lung disease ILD in thoracic computed tomography CT developed in this study a texture analysis-based method for accurate segmentation of lungs with severe ILD

  5. The Role of Silicon Interstitials in the Formation of Boron-Oxygen Defects in Crystalline Silicon

    E-Print Network [OSTI]

    The Role of Silicon Interstitials in the Formation of Boron-Oxygen Defects in Crystalline Silicon@ise.fhg.de Keywords: crystalline silicon, Czochralski, boron-oxygen defect, silicon interstitial Abstract. Oxygen-rich crystalline silicon materials doped with boron are plagued by the presence of a well-known carrier

  6. Hydrogen and chloride ions effects on the automobile interstitial-free steel corrosion

    E-Print Network [OSTI]

    Volinsky, Alex A.

    1 Hydrogen and chloride ions effects on the automobile interstitial-free steel corrosion L.Q. Guo 1 Abstract The effects of hydrogen and chloride ions on the corrosion behavior of interstitial-free steel and the corrosion potentials drop sharply. Under a given hydrogen charging current density, the drops of the pitting

  7. Classification of interstitial lung disease patterns with topological texture features

    E-Print Network [OSTI]

    Huber, Markus B; Leinsinger, Gerda; Ray, Lawrence A; Wismüller, Axel; 10.1117/12.844318

    2010-01-01

    Topological texture features were compared in their ability to classify morphological patterns known as 'honeycombing' that are considered indicative for the presence of fibrotic interstitial lung diseases in high-resolution computed tomography (HRCT) images. For 14 patients with known occurrence of honey-combing, a stack of 70 axial, lung kernel reconstructed images were acquired from HRCT chest exams. A set of 241 regions of interest of both healthy and pathological (89) lung tissue were identified by an experienced radiologist. Texture features were extracted using six properties calculated from gray-level co-occurrence matrices (GLCM), Minkowski Dimensions (MDs), and three Minkowski Functionals (MFs, e.g. MF.euler). A k-nearest-neighbor (k-NN) classifier and a Multilayer Radial Basis Functions Network (RBFN) were optimized in a 10-fold cross-validation for each texture vector, and the classification accuracy was calculated on independent test sets as a quantitative measure of automated tissue characteriza...

  8. Needle-free interstitial fluid acquisition using a Lorentz-force actuated jet injector

    E-Print Network [OSTI]

    Chang, Jean H

    2014-01-01

    Interstitial fluid (ISF) provides information on a patient's health as it contains regulatory molecules that are correlated with disease-related processes. However, current ISF acquisition techniques can be slow, resulting ...

  9. A theoretical analysis of interstitial hydrogen : pressure-composition-temperature, chemical potential, enthalpy and entropy

    E-Print Network [OSTI]

    Orondo, Peter Omondi

    2012-01-01

    We provide a first principles analysis of the physics and thermodynamics of interstitial hydrogen in metal. By utilizing recent advances in Density Functional Theory (DFT) to get state energies of the metal-hydrogen system, ...

  10. Interstitial flow influences direction of tumor cell migration through competing mechanisms

    E-Print Network [OSTI]

    Charest, Joseph L.

    Interstitial flow is the convective transport of fluid through tissue extracellular matrix. This creeping fluid flow has been shown to affect the morphology and migration of cells such as fibroblasts, cancer cells, endothelial ...

  11. Urban temporal storage : re-thinking the public domain using interstitial space in NYC

    E-Print Network [OSTI]

    Uchida, Mio

    2010-01-01

    This thesis aims to rethink the notion of public space and civic duty in the city. By using interstitial, underused spaces, without disputing present urban and legal status, the thesis wants to accomodate services for the ...

  12. A STUDY OF PRECIPITATION IN INTERSTITIAL ALLOYS. I. PRECIPITATION SEQUENCE IN Ta-C ALLOYS

    E-Print Network [OSTI]

    Dahmen, U.

    2010-01-01

    Acta Meta11urgica A STUDY OF PRECIPITATION IN INTERSTITIALALLOYS. I. PRECIPITATION SEQUENCE IN Ta-C ALLOYS U. Dahmen,ENG-48 y A Study of Precipitation in Interstitial Alloys. I.

  13. Measurements of the oxidation state and concentration of plutonium in interstitial waters of the Irish Sea

    SciTech Connect (OSTI)

    Nelson, D.M.; Lovett, M.B.

    1980-01-01

    The question of plutonium movement in interstitial waters resulting from diffusion along concentration gradients or from advective flow is addressed. The results of measurements of both the concentration and the oxidation state of plutonium in interstitial water collected from sediments near the Windscale discharge, in the solid phases of these sediments and in seawater and suspended solids collected at the coring locations are discussed. (ACR)

  14. Influence of interstitial Mn on magnetism in room-temperature ferromagnet Mn(1+delta)Sb

    SciTech Connect (OSTI)

    Taylor, Alice E [ORNL; Berlijn, Tom [ORNL; Hahn, Steven E [ORNL; May, Andrew F [ORNL; Williams, Travis J [ORNL; Poudel, Lekhanath N [ORNL; Calder, Stuart A [ORNL; Fishman, Randy Scott [ORNL; Stone, Matthew B [ORNL; Aczel, Adam A [ORNL; Cao, Huibo [ORNL; Lumsden, Mark D [ORNL; Christianson, Andrew D [ORNL

    2015-01-01

    We report elastic and inelastic neutron scattering measurements of the high-TC ferromagnet Mn(1+delta)Sb. Measurements were performed on a large, TC = 434 K, single crystal with interstitial Mn content of delta=0.13. The neutron diffraction results reveal that the interstitial Mn has a magnetic moment, and that it is aligned antiparallel to the main Mn moment. We perform density functional theory calculations including the interstitial Mn, and find the interstitial to be magnetic in agreement with the diffraction data. The inelastic neutron scattering measurements reveal two features in the magnetic dynamics: i) a spin-wave-like dispersion emanating from ferromagnetic Bragg positions (H K 2n), and ii) a broad, non-dispersive signal centered at forbidden Bragg positions (H K 2n+1). The inelastic spectrum cannot be modeled by simple linear spin-wave theory calculations, and appears to be significantly altered by the presence of the interstitial Mn ions. The results show that the influence of the int

  15. Machine therapy

    E-Print Network [OSTI]

    Dobson, Kelly E. (Kelly Elizabeth), 1970-

    2007-01-01

    Machine Therapy is a new practice combining art, design, psychoanalysis, and engineering work in ways that access and reveal the vital, though often unnoticed, relevance of people's interactions and relationships with ...

  16. Surface-induced charge at the Ge (001) surface and its interaction with self-interstitials

    SciTech Connect (OSTI)

    Kamiyama, Eiji; Sueoka, Koji [Department of Communication Engineering, Okayama Prefectural University, 111 Kuboki, Soja-shi, Okayama-ken 719-1197 (Japan); Vanhellemont, Jan [Department of Solid State Sciences, Ghent University, B-9000 Gent (Belgium)

    2014-02-21

    The Ge (001) surface with dimer structure, is negatively charged while into the bulk, positive charges are observed even deeper than the fifteenth layer from the surface. This is different from the Si case. This charge distribution can lead to the repulsion of positively charged self-interstitials by the positively charged near surface layer in an implantation or irradiation process. Self-interstitial reflection by Ge surfaces had been proposed to explain the results of diffusion experiments during irradiation whereby positively charged self-interstitials are generated by collisions of highly energetic particles with Ge atoms. We investigated different Ge (001) surface comparing an as-cleaved surface with dangling bonds to a surface with dimer structure, and to a surface terminated by hydrogen atoms. The effect of these different surface terminations on the surface-induced charges in the near surface bulk were calculated by ab initio techniques.

  17. Segregation of Mn2+ Dopants as Interstitials in SrTiO3 Grain Boundaries

    SciTech Connect (OSTI)

    Yang, Hao; Kotula, Paul G.; Sato, Yukio; Chi, Miaofang; Ikuhara, Yuichi; Browning, Nigel D.

    2013-10-03

    Mn doped SrTiO3 shows promising magnetic and electrical properties, but the doping mechanism remains unclear. In this research Mn4+ is found to substitute Ti in bulk SrTiO3, but Mn2+ segregates inside grain boundaries at both Sr and interstitial sites. Mn interstitial doping has never been reported, but is found possible with the formation of Sr vacancies. This finding is significantly different from the amphoteric doping of Mn2+ substituting Sr and Mn4+ substituting Ti sites, therefore leads to different understanding on the defect mediated electrical and magnetic properties of transition metal doped perovskites.

  18. Relation between thermal expansion and interstitial formation energy in pure Fe and Cr

    E-Print Network [OSTI]

    term, i.e. the contribution to the total energy from the valence electron density. Consequently we needRelation between thermal expansion and interstitial formation energy in pure Fe and Cr Janne Wallenius a,b,*, Pa¨r Olsson b , Christina Lagerstedt a a Department of Nuclear and Reactor Physics, KTH

  19. Precipitation of interstitial iron in multicrystalline silicon AnYao Liu1, a

    E-Print Network [OSTI]

    Precipitation of interstitial iron in multicrystalline silicon AnYao Liu1, a and Daniel Macdonald1, multicrystalline silicon, precipitation, supersaturation, spatial distribution Abstract The internal gettering of iron in silicon via iron precipitation at low processing temperatures is known to improve solar cell

  20. SU-E-T-574: Fessiblity of Using the Calypso System for HDR Interstitial Catheter Reconstruction

    SciTech Connect (OSTI)

    Li, J S; Ma, C [Fox Chase Cancer Center, Philadelphia, PA (United States)

    2014-06-01

    Purpose: It is always a challenge to reconstruct the interstitial catheter for high dose rate (HDR) brachytherapy on patient CT or MR images. This work aims to investigate the feasibility of using the Calypso system (Varian Medical, CA) for HDR catheter reconstruction utilizing its accuracy on tracking the electromagnetic transponder location. Methods: Experiment was done with a phantom that has a HDR interstitial catheter embedded inside. CT scan with a slice thickness of 1.25 mm was taken for this phantom with two Calypso beacon transponders in the catheter. The two transponders were connected with a wire. The Calypso system was used to record the beacon transponders’ location in real time when they were gently pulled out with the wire. The initial locations of the beacon transponders were used for registration with the CT image and the detected transponder locations were used for the catheter path reconstruction. The reconstructed catheter path was validated on the CT image. Results: The HDR interstitial catheter was successfully reconstructed based on the transponders’ coordinates recorded by the Calypso system in real time when the transponders were pulled in the catheter. After registration with the CT image, the shape and location of the reconstructed catheter are evaluated against the CT image and the result shows an accuracy of 2 mm anywhere in the Calypso detectable region which is within a 10 cm X 10 cm X 10 cm cubic box for the current system. Conclusion: It is feasible to use the Calypso system for HDR interstitial catheter reconstruction. The obstacle for its clinical usage is the size of the beacon transponder whose diameter is bigger than most of the interstitial catheters used in clinic. Developing smaller transponders and supporting software and hardware for this application is necessary before it can be adopted for clinical use.

  1. IEEE JOURNAL OF PHOTOVOLTAICS, VOL. 4, NO. 5, SEPTEMBER 2014 1185 Imaging As-Grown Interstitial Iron Concentration

    E-Print Network [OSTI]

    IEEE JOURNAL OF PHOTOVOLTAICS, VOL. 4, NO. 5, SEPTEMBER 2014 1185 Imaging As-Grown Interstitial of one or more of the figures in this paper are available online at http://ieeexplore.ieee.org. Digital

  2. Chemical composition of interstitial waters from the Japan Sea, ODP Leg 128

    SciTech Connect (OSTI)

    Sturz, A. ); Von Breymann, M.; Dunbar, R. )

    1990-06-01

    During ODP Leg 128, interstitial waters were recovered from Oki Ridge (Site 798) and Kita-Yamato Trough (Site 799) sediment, Sea of Japan. Interstitial water chemical composition reflects diagenetic processes. Evidence indicating organic matter degradation processes includes sulfate depletion, high ammonium concentrations, and shallow maxima of dissolved phosphate. Rapid alkalinity increases in the uppermost sections of the sediments are accompanied by decreases in dissolved calcium, reflecting inorganic calcite precipitation. Authigenic dolomitization results in changes in slopes of the Mg/Ca molar ratios with depth. The opal-A/opal-CT transition is documented by the concentration depth profiles of dissolved silica and lithium. Dolomitization precedes the opal-A/opal-CT transition at both sites. Kita-Yamato Trough sediments show an abrupt change in the compositional character of the pore fluids below 435 mbsf, which coincides with the occurrence of low porosity and high bulk density layers composed of dolomite and opal-CT. These layers impede to some extent diffusional communication with the overlying interstitial waters. The interstitial waters in sediments below 435 mbsf have chloride concentrations of 504-515 mM, significantly lower than that of modern day Japan Sea water (540 mM). The presence of low chloride waters within Miocene age sediments may indicate: (1) diagenetic reactions that involve the release of exchangeable and structural bound water from clay minerals and/or opal-A, (2) Miocene connate brackish lake water, (3) phase separation of hydrothermal fluids associated with rifting, (4) potential effects of clay membrane filtration in a high pressure zone.

  3. NEWS & VIEWS Glass dynamics

    E-Print Network [OSTI]

    Weeks, Eric R.

    NEWS & VIEWS Glass dynamics Diverging views on glass transition Gregory B. mc.mckenna@ttu.edu T he glass transition is one of the most intriguing phenomena in the world of soft condensed matter. Despite decades of study, many aspects of the behaviour of glass-forming liquids remain elusive

  4. World Views From fragmentation

    E-Print Network [OSTI]

    World Views From fragmentation to integration Diederik Aerts Leo Apostel Bart De Moor Staf in 1994 by VUB Press: Brussels Internet edition by Clément Vidal and Alexander Riegler #12;World Views 2................................................................................................................... 5 1.1 The fragmentation of our world

  5. Cinnamaldehyde impairs high glucose-induced hypertrophy in renal interstitial fibroblasts

    SciTech Connect (OSTI)

    Chao, Louis Kuoping [Department of Cosmeceutics, China Medical University, Taichung 404, Taiwan (China); Chang, W.-T.; Shih, Y.-W. [Department of Biological Science and Technology, Chung Hwa University of Medical Technology, Tainan 717, Taiwan (China); Huang, J.-S., E-mail: jaushyang12@hotmail.co [Department of Biological Science and Technology, Chung Hwa University of Medical Technology, Tainan 717, Taiwan (China)

    2010-04-15

    Cinnamaldehyde is a major and a bioactive compound isolated from the leaves of Cinnamomum osmophloeum kaneh. To explore whether cinnamaldehyde was linked to altered high glucose (HG)-mediated renal tubulointerstitial fibrosis in diabetic nephropathy (DN), the molecular mechanisms of cinnamaldehyde responsible for inhibition of HG-induced hypertrophy in renal interstitial fibroblasts were examined. We found that cinnamaldehyde caused inhibition of HG-induced cellular mitogenesis rather than cell death by either necrosis or apoptosis. There were no changes in caspase 3 activity, cleaved poly(ADP-ribose) polymerase (PARP) protein expression, and mitochondrial cytochrome c release in HG or cinnamaldehyde treatments in these cells. HG-induced extracellular signal-regulated kinase (ERK)/c-Jun N-terminal kinase (JNK)/p38 mitogen-activated protein kinase (MAPK) (but not the Janus kinase 2/signal transducers and activators of transcription) activation was markedly blocked by cinnamaldehyde. The ability of cinnamaldehyde to inhibit HG-induced hypertrophy was verified by the observation that it significantly decreased cell size, cellular hypertrophy index, and protein levels of collagen IV, fibronectin, and alpha-smooth muscle actin (alpha-SMA). The results obtained in this study suggest that cinnamaldehyde treatment of renal interstitial fibroblasts that have been stimulated by HG reduces their ability to proliferate and hypertrophy through mechanisms that may be dependent on inactivation of the ERK/JNK/p38 MAPK pathway.

  6. NEWS AND VIEWS PERSPECTIVE

    E-Print Network [OSTI]

    Mahler, D. Luke

    NEWS AND VIEWS PERSPECTIVE Niche diversification follows key innovation in Antarctic fish radiation Oxford Street, Cambridge MA 02138, USA Antarctic notothenioid fishes provide a fascinating evolu- tionary diversification has occurred repeatedly and in parallel. Keywords: community ecology, fish, macroevolution, phylo

  7. Correlation between the electronic structures and diffusion paths of interstitial defects in semiconductors: The case in CdTe

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Ma, Jie; Yang, Jihui; Da Silva, J. L.F.; Wei, Su-Huai

    2014-10-30

    Using first-principles calculations, we study the diffusions of interstitial defects Cd, Cu, Te, and Cl in CdTe. We find that the diffusion behavior is strongly correlated with the electronic structure of the interstitial diffuser. For Cd and Cu, because the defect state is the non-degenerated slike state under Td symmetry, the diffusions are almost along the [111] directions between the tetrahedral sites, although the diffusion of Cu shows some deviation due to the s - d coupling. The diffusions of the neutral and charged Cd and Cu follow similar paths. However, for Te and Cl atoms, because the defect statemore »is the degenerated p-like state under Td symmetry, large distortions occur. Therefore, the diffusion paths are very different from those of Cd and Cu interstitials, and depend strongly on the charge states of the interstitial atoms. For Te, we find that the distortion is mostly stabilized by the crystal-field splitting, but for Cl, the exchange splitting plays a more important role.« less

  8. Correlation between the electronic structures and diffusion paths of interstitial defects in semiconductors: The case in CdTe

    SciTech Connect (OSTI)

    Ma, Jie; Yang, Jihui; Da Silva, J. L.F.; Wei, Su-Huai

    2014-10-30

    Using first-principles calculations, we study the diffusions of interstitial defects Cd, Cu, Te, and Cl in CdTe. We find that the diffusion behavior is strongly correlated with the electronic structure of the interstitial diffuser. For Cd and Cu, because the defect state is the non-degenerated slike state under Td symmetry, the diffusions are almost along the [111] directions between the tetrahedral sites, although the diffusion of Cu shows some deviation due to the s - d coupling. The diffusions of the neutral and charged Cd and Cu follow similar paths. However, for Te and Cl atoms, because the defect state is the degenerated p-like state under Td symmetry, large distortions occur. Therefore, the diffusion paths are very different from those of Cd and Cu interstitials, and depend strongly on the charge states of the interstitial atoms. For Te, we find that the distortion is mostly stabilized by the crystal-field splitting, but for Cl, the exchange splitting plays a more important role.

  9. Correlation between the electronic structures and diffusion paths of interstitial defects in semiconductors: The case in CdTe

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Ma, Jie [National Renewable Energy Lab. (NREL), Golden, CO (United States); Yang, Jihui [National Renewable Energy Lab. (NREL), Golden, CO (United States); Da Silva, J. L.F. [Univ. of Sao Paulo, Sao Carlos (Brazil). Sao Carlos Institute of Chemistry; Wei, Su-Huai [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2014-10-01

    Using first-principles calculations, we study the diffusions of interstitial defects Cd, Cu, Te, and Cl in CdTe. We find that the diffusion behavior is strongly correlated with the electronic structure of the interstitial diffuser. For Cd and Cu, because the defect state is the non-degenerated slike state under Td symmetry, the diffusions are almost along the [111] directions between the tetrahedral sites, although the diffusion of Cu shows some deviation due to the s - d coupling. The diffusions of the neutral and charged Cd and Cu follow similar paths. However, for Te and Cl atoms, because the defect state is the degenerated p-like state under Td symmetry, large distortions occur. Therefore, the diffusion paths are very different from those of Cd and Cu interstitials, and depend strongly on the charge states of the interstitial atoms. For Te, we find that the distortion is mostly stabilized by the crystal-field splitting, but for Cl, the exchange splitting plays a more important role.

  10. Pressure effect on stabilities of self-Interstitials in HCP structures

    SciTech Connect (OSTI)

    Peng, Qing; Ji, Wei; Lian, Jie; Chen, Xiao-jia; Huang, Hanchen; Gao, Fei; De, Suvranu

    2014-07-18

    The self-interstitial atoms (SIAs) mediate the evolution of micro-structures which is crucial in understanding the instabilities of hexagonal close packed (HCP) structures. Taken zirconium as a prototype, we investigate the pressure effect on the stabilities of SIAs using first-principles calculations based on density-functional theory. We found that the pressure greatly affects the stability of the SIAs. The SIAs in basal planes are more stable to changes in pressure. The most stable SIA configuration changes from basal octahedral (BO) to octahedral (O) at pressure of 21 GPa. The lowest formation enthalpy configuration switches from BO to S (split-dumbbell) at P = 30 GPa. Our results reveal that it is important to take the pressure effect into account when predicting the micro-structural evolution of HCP structures.

  11. Quality Assurance of Multifractionated Pelvic Interstitial Brachytherapy for Postoperative Recurrences of Cervical Cancers: A Prospective Study

    SciTech Connect (OSTI)

    Shukla, Pragya; Chopra, Supriya; Engineer, Reena; Mahantshetty, Umesh; Paul, Siji Nojin; Phurailatpam, Reena; SV, Jamema; Shrivastava, Shyam K.

    2012-03-15

    Purpose: To evaluate three-dimensional needle displacements during multifractionated interstitial brachytherapy (BT) for cervical cancers. Methods and Materials: Patients scheduled to undergo pelvic interstitial BT for postoperative and or postradiation vault recurrences were included from November 2009 to December 2010. All procedures were performed under spinal anesthesia. Postprocedure BT planning CT scans were obtained with patients in supine position with arms on the chest (interslice thickness of 3 mm). Thereafter, verification CT was repeated at every alternate fraction. Needle displacements were measured in reference to a relocatable bony point. The mean cranial, caudal, anteroposterior, and mediolateral displacements were recorded. Statistical significance of mean interfraction displacements was evaluated with Wilcoxon Test. Results: Twenty patients were included. Seventeen received boost BT (20 Gy/5 fractions/3 days) after external radiation, three received radical BT alone (36 Gy/9 fractions/5-8 days). An average of three scans (range, 2-3) were available per patient, and 357 needle displacements were analyzed. For the entire study cohort, the average of mean needle displacement was 2.5 mm (range, 0-7.4), 17.4 mm (range, 0-27.9), 1.7 mm (range, 0-6.7), 2.1 mm (range, 0-9.5), 1.7 mm (range, 0-9.3), and 0.6 mm (range, 0-7.8) in cranial, caudal, anterior, posterior, right, and left directions, respectively. The mean displacement in the caudal direction was higher between Days 1 and 2 than that between Days 2 and 3 (13.4 mm vs. 3.8 mm; p = 0.01). The average caudal displacements were no different between reirradiation and boost cohort (15.2 vs. 17.8 mm). Conclusions: Clinically significant caudal displacements occur during multifractionated pelvic brachytherapy. Optimal margins need to be incorporated while preplanning brachytherapy to account for interfraction displacements.

  12. Workshop on neutron capture therapy

    SciTech Connect (OSTI)

    Fairchild, R.G.; Bond, V.P.

    1986-01-01

    Potentially optimal conditions for Neutron Capture Therapy (NCT) may soon be in hand due to the anticipated development of band-pass filtered beams relatively free of fast neutron contaminations, and of broadly applicable biomolecules for boron transport such as porphyrins and monoclonal antibodies. Consequently, a number of groups in the US are now devoting their efforts to exploring NCT for clinical application. The purpose of this Workshop was to bring these groups together to exchange views on significant problems of mutual interest, and to assure a unified and effective approach to the solutions. Several areas of preclinical investigation were deemed to be necessary before it would be possible to initiate clinical studies. As neither the monomer nor the dimer of sulfhydryl boron hydride is unequivocally preferable at this time, studies on both compounds should be continued until one is proven superior.

  13. High-Risk Prostate Cancer With Gleason Score 8-10 and PSA Level {<=}15 ng/ mL Treated With Permanent Interstitial Brachytherapy

    SciTech Connect (OSTI)

    Fang, L. Christine [Department of Radiation Oncology, University of Washington, Seattle, WA (United States); Merrick, Gregory S., E-mail: gmerrick@urologicresearchinstitute.org [Schiffler Cancer Center, Wheeling Jesuit University, Wheeling, WV (United States); Butler, Wayne M.; Galbreath, Robert W.; Murray, Brian C.; Reed, Joshua L. [Schiffler Cancer Center, Wheeling Jesuit University, Wheeling, WV (United States); Adamovich, Edward [Department of Pathology, Wheeling Hospital, Wheeling, WV (United States); Wallner, Kent E. [Puget Sound Veterans Affairs Hospital, Seattle, WA (United States)

    2011-11-15

    Purpose: With widespread prostate-specific antigen (PSA) screening, there has been an increase in men diagnosed with high-risk prostate cancer defined by a Gleason score (GS) {>=}8 coupled with a relatively low PSA level. The optimal management of these patients has not been defined. Cause-specific survival (CSS), biochemical progression-free survival (bPFS), and overall survival (OS) were evaluated in brachytherapy patients with a GS {>=}8 and a PSA level {<=}15 ng/mL with or without androgen-deprivation therapy (ADT). Methods and Materials: From April 1995 to October 2005, 174 patients with GS {>=}8 and a PSA level {<=}15 ng/mL underwent permanent interstitial brachytherapy. Of the patients, 159 (91%) received supplemental external beam radiation, and 113 (64.9%) received ADT. The median follow-up was 6.6 years. The median postimplant Day 0 minimum percentage of the dose covering 90% of the target volume was 121.1% of prescription dose. Biochemical control was defined as a PSA level {<=}0.40 ng/mL after nadir. Multiple parameters were evaluated for impact on survival. Results: Ten-year outcomes for patients without and with ADT were 95.2% and 92.5%, respectively, for CSS (p = 0.562); 86.5% and 92.6%, respectively, for bPFS (p = 0.204); and 75.2% and 66.0%, respectively, for OS (p = 0.179). The median post-treatment PSA level for biochemically controlled patients was <0.02 ng/mL. Multivariate analysis failed to identify any predictors for CSS, whereas bPFS and OS were most closely related to patient age. Conclusions: Patients with GS {>=}8 and PSA level {<=}15 ng/mL have excellent bPFS and CSS after brachytherapy with supplemental external beam radiotherapy. The use of ADT did not significantly impact bPFS, CSS, or OS.

  14. Structure of self-interstitial atom clusters in iron and copper

    SciTech Connect (OSTI)

    Takahashi, Akiyuki [Department of Mechanical Engineering, Faculty of Science and Technology, Tokyo University of Science, 2641 Yamazaki, Noda-shi, Chiba 278-8510 (Japan); Ghoniem, Nasr M. [Department of Mechanical and Aerospace Engineering, University of California-Los Angeles, Los Angeles, California 90095 (United States)

    2009-11-01

    The dislocation core structure of self-interstitial atom (SIA) clusters in bcc iron and fcc copper is determined using the hybrid ab initio continuum method of Banerjee et al. [Philos. Mag. 87, 4131 (2007)]. To reduce reliance on empirical potentials and to facilitate predictions of the effects of local chemistry and stress on the structure of defects, we present here a hybrid extension of the Peierls-Nabarro continuum model, with lattice resistance to slip determined separately from ab initio calculations. A method is developed to reconstruct atomic arrangements and geometry of SIA clusters from the hybrid model. The results are shown to compare well with molecular-dynamics simulations. In iron, the core structure does not show dependence on the size of the self-interstitial cluster, and is nearly identical to that of a straight edge dislocation. However, the core structure of SIA clusters in Cu is shown to depend strongly on the cluster size. Small SIA clusters are found to have nondissociated compact dislocation cores, with a strong merging of Shockley partial dislocations and a relatively narrow stacking fault (SF) region. The compact nature of the SIA core in copper is attributed to the strong dependence of the self-energy on the cluster size. As the number of atoms in the SIA cluster increases, Shockley partial dislocations separate and the SF region widens, rendering the SIA core structure to that of an edge dislocation. The separation distance between the two partials widens as the cluster size increases, and tends to the value of a straight edge dislocation for cluster sizes above 400 atoms. The local stress is found to have a significant effect on the atomic arrangements within SIA clusters in copper and the width of the stacking faults. An applied external shear can delocalize the core of an SIA cluster in copper, with positive shear defined to be on the (111) plane along the [112] direction. For an SIA cluster containing 1600 atoms, a positive 1 GPa shear stress delocalizes the cluster and expands the SF to 30b, while a negative shear stress of 2 GPa contracts the core to less than 5b, where b is the Burgers vector magnitude.

  15. Unfaulting mechanism of trapped self-interstitial atom clusters in bcc Fe: A kinetic study based on the potential energy landscape

    E-Print Network [OSTI]

    Yildiz, Bilge

    We report on the complete unfaulting mechanism of a trapped self-interstitial atom cluster in the form of a nonparallel configuration (NPC), investigated using the autonomous basin climbing (ABC) method. A detailed set of ...

  16. The effect of strain and path change on the mechanical properties and microstructural evolution of ultrafine grained interstitial free steel during equal channel angular extrusion (ECAE) 

    E-Print Network [OSTI]

    Sutter, Steven George

    2007-04-25

    The objectives of this study were to examine the effect of strain and path change on the microstructural evolution of ultrafine grained interstitial free (IF) steel during equal channel angular extrusion (ECAE); to determine the mechanical...

  17. Mining Views: Database Views for Data Mining Hendrik Blockeel #1

    E-Print Network [OSTI]

    Antwerpen, Universiteit

    Mining Views: Database Views for Data Mining Hendrik Blockeel #1 , Toon Calders 2 , Elisa Fromont adriana.prado}@ua.ac.be Abstract-- We present a system towards the integration of data mining mining views. We show that several types of patterns and models over the data, such as itemsets

  18. Mining Views: Database Views for Data Mining Hendrik Blockeel1

    E-Print Network [OSTI]

    Antwerpen, Universiteit

    Mining Views: Database Views for Data Mining Hendrik Blockeel1 , Toon Calders2 , Elisa Fromont1 model towards the inte- gration of data mining into relational database systems, based on the so called virtual mining views. We show that several types of patterns and models over the data, such as itemsets

  19. GROUP THERAPY Syracuse University

    E-Print Network [OSTI]

    McConnell, Terry

    your individual needs. In a group, up to eight students meet with one or two group therapists. MostGROUP THERAPY Syracuse University Counseling Center 200 Walnut Place Phone: 315-443-4715 Fax: 315-443-4276 counselingcenter.syr.edu WHAT STUDENTS SAY ABOUT GROUP THERAPY I was really anxious about joining a group

  20. Lasers in Surgery and Medicine 38:427434 (2006) Preliminary Results of Interstitial Motexafin

    E-Print Network [OSTI]

    Yodh, Arjun G.

    2006-01-01

    Lutetium-Mediated PDT for Prostate Cancer K.L. Du, MD, PhD,1 R. Mick, MS,2 T.M. Busch, PhD,1 T.C. Zhu, Ph, using motexafin lutetium-mediated PDT for recurrent prostate adenocarcinoma. Dosimetry of light fluence Wiley-Liss, Inc. Key words: photodynamic therapy; prostate cancer; adenocarcinoma; motexafin lutetium

  1. Protective laser beam viewing device

    DOE Patents [OSTI]

    Neil, George R.; Jordan, Kevin Carl

    2012-12-18

    A protective laser beam viewing system or device including a camera selectively sensitive to laser light wavelengths and a viewing screen receiving images from the laser sensitive camera. According to a preferred embodiment of the invention, the camera is worn on the head of the user or incorporated into a goggle-type viewing display so that it is always aimed at the area of viewing interest to the user and the viewing screen is incorporated into a video display worn as goggles over the eyes of the user.

  2. SU-D-16A-07: Photobleaching Predicts Necrosis in Interstitial PDT

    SciTech Connect (OSTI)

    Kim, M; Finlay, J; Liu, B; Zhu, T [University of Pennsylvania, Philadelphia, PA (United States)

    2014-06-01

    Purpose: Dosimetry for PDT has proven to be a challenge thus far, and for prediction of PDT outcome, a singlet oxygen model based on fundamental photophysical parameters has been developed. Previously, the photobleaching effect of photosensitizers was taken into account in the singlet oxygen explicit dosimetry model; here we report of direct measurements of photobleaching in the same model to assess the conditions under which implicit dosimetry using photobleaching can serve as an intermediate surrogate for PDT damage. Methods: Fluorescence spectra were measured interstitially in sensitized mouse tumors prior to after irradiation via a cylindrical diffuser. Photobleaching was determined by the relative decrease in fluorescence amplitude from the initial pre-treatment measurement. Spectra were analyzed by singular value decomposition to determine the photosensitizer concentration. Different photosensitizers were used to see the effect of photobleaching on PDT outcome and the impact of fluence on photobleaching. The drugs used were BPD (at two drug-light intervals), HPPH, and Photofrin. PDT outcome was determined by tumor necrosis radii measured upon sectioning and staining of treated tumors. Results: Post-PDT photosentizer concentrations were compared to initial pre-PDT photosensitizer concentrations, and the decrease was greater with a higher fluence measured during treatment. Furthermore, photobleaching and necrosis radius were found to be positively correlated. The relationship between photobleaching and necrosis radius is sensitizer-dependent, however the differences among sensitizers can be understood in terms of their respective photophysical parameters. Conclusions: Photobleaching is predictive of PDT outcome, but a comprehensive singlet oxygen model, has the potential to further improve the prediction of PDT outcome and the understanding of implicit dosimetry.

  3. Mountain View, California: Fiat Res Publica

    E-Print Network [OSTI]

    Tung, Gregory

    1989-01-01

    Mountain View, California: Fiat Res Publica Gregory Tungundifferen­ tiated. In Mountain View, California (populationtoward San Francisco. Mountain View is avoiding a "just say

  4. False color viewing device

    DOE Patents [OSTI]

    Kronberg, J.W.

    1991-05-08

    This invention consists of a viewing device for observing objects in near-infrared false-color comprising a pair of goggles with one or more filters in the apertures, and pads that engage the face for blocking stray light from the sides so that all light reaching, the user`s eyes come through the filters. The filters attenuate most visible light and pass near-infrared (having wavelengths longer than approximately 700 nm) and a small amount of blue-green and blue-violet (having wavelengths in the 500 to 520 nm and shorter than 435 nm, respectively). The goggles are useful for looking at vegetation to identify different species and for determining the health of the vegetation, and to detect some forms of camouflage.

  5. False color viewing device

    DOE Patents [OSTI]

    Kronberg, J.W.

    1992-10-20

    A viewing device for observing objects in near-infrared false-color comprising a pair of goggles with one or more filters in the apertures, and pads that engage the face for blocking stray light from the sides so that all light reaching the user's eyes come through the filters. The filters attenuate most visible light and pass near-infrared (having wavelengths longer than approximately 700 nm) and a small amount of blue-green and blue-violet (having wavelengths in the 500 to 520 nm and shorter than 435 nm, respectively). The goggles are useful for looking at vegetation to identify different species and for determining the health of the vegetation, and to detect some forms of camouflage. 7 figs.

  6. False color viewing device

    DOE Patents [OSTI]

    Kronberg, James W. (108 Independent Blvd., Aiken, SC 29801)

    1992-01-01

    A viewing device for observing objects in near-infrared false-color comprising a pair of goggles with one or more filters in the apertures, and pads that engage the face for blocking stray light from the sides so that all light reaching the user's eyes come through the filters. The filters attenuate most visible light and pass near-infrared (having wavelengths longer than approximately 700 nm) and a small amount of blue-green and blue-violet (having wavelengths in the 500 to 520 nm and shorter than 435 nm, respectively). The goggles are useful for looking at vegetation to identify different species and for determining the health of the vegetation, and to detect some forms of camouflage.

  7. Viewing Conditions and Chromatic Adaptation

    E-Print Network [OSTI]

    Majumder, Aditi

    Linear nonlinear #12;2 Viewing field Self-luminous displays CRT, LCD Reflective media Painting Viewing: Adapting stimulus Subscript E: Equal energy illumination #12;13 Fairchild's model (1991) Inter channel brightness #12;6 11 Definition of Color Appearance Model so much description of color such as: wavelength

  8. Comparison of precipitate behaviors in ultra-low carbon, titanium-stabilized interstitial free steel sheets under different annealing processes

    SciTech Connect (OSTI)

    Shi, J.; Wang, X.

    1999-12-01

    Ultra-low carbon, titanium-stabilized interstitial free (ULC Ti-IF) steel sheets are widely used in the automobile industry because of excellent deep drawability. The annealing process is critical to their final property, and there are two different annealing processes used in industrial production of interstitial free (IF) steel sheets, namely batch annealing and continuous annealing. In this study, precipitation behaviors of titanium IF steels, that is, TiN, TiS, Ti{sub 4}(CS){sub 2}, and TiC, the size and dispersion of TiN, TiS, and Ti{sub 4}(CS){sub 2} remained almost unchanged after either annealing process. Conversely, the average size of a TiC particle increased substantially after both annealing processes, while TiC after continuous annealing was larger than that after batch annealing due to the higher heating temperature of continuous annealing. Two new particles, FeTiP and (Ti, Mn)S, were also observed in the batch annealing process but not in continuous annealing. The structure of FeTiP and (Ti, Mn)S were studied, and furthermore the evolution of FeTiP precipitation was found to be closely related to recrystallization in batch annealing. Finally, the interrelation among processing parameters, precipitation behaviors, and final property was studied.

  9. PHYSICAL THERAPY Degree Program

    E-Print Network [OSTI]

    Alpay, S. Pamir

    Doctor of PHYSICAL THERAPY Degree Program In 1952, the University of Connecticut became the first Neag School of Education University of Connecticut 2095 Hillside Road, U-1110 Storrs, Connecticut 06269 #12;What We Look For: All applicants must meet the University of Connecticut Graduate School admission

  10. Landscape viewing in metropolitan Boston

    E-Print Network [OSTI]

    Teas, Wendy Ann

    1990-01-01

    This thesis recognizes the importance of landscape viewing, especially as a solitary act of contemplation. It suggests the creation of a place from which to gaze upon a vast landscape. It postulates that an observation ...

  11. A Regulator's View of Cogeneration 

    E-Print Network [OSTI]

    Shanaman, S. M.

    1982-01-01

    of the total national electric generation. In view of the energy requirements of Pennsylvania's industry and the impact of increasing energy costs on employment the Commission directed its technical staff to investigate the potential for industrial cogeneration...

  12. RAPID ASSESSMENT OF AS-GROWN INTERSTITIAL IRON CONCENTRATION AND IMPACT ON P-TYPE SILICON BLOCKS VIA SPECTRAL PHOTOLUMINESCENCE IMAGING

    E-Print Network [OSTI]

    , Canberra, Australia 3 Fraunhofer Institute for Solar Energy Systems, Freiburg, Germany 4 BT Imaging Pty Ltd South Wales, Sydney, Australia 2 Research School of Engineering, The Australian National University to the further understanding of the crystallization and following cell processing. Interstitial iron has been

  13. Simulation of xenon, uranium vacancy and interstitial diffusion and grain boundary segregation in UO2

    SciTech Connect (OSTI)

    Andersson, Anders D.; Tonks, Michael R.; Casillas, Luis; Nerikar, Pankaj; Vyas, Shyam; Uberuaga, Blas P.; Stanek, Christopher R.

    2014-10-31

    In light water reactor fuel, gaseous fission products segregate to grain boundaries, resulting in the nucleation and growth of large intergranular fission gas bubbles. Based on the mechanisms established from density functional theory (DFT) and empirical potential calculations 1, continuum models for diffusion of xenon (Xe), uranium (U) vacancies and U interstitials in UO2 have been derived for both intrinsic conditions and under irradiation. Segregation of Xe to grain boundaries is described by combining the bulk diffusion model with a model for the interaction between Xe atoms and three different grain boundaries in UO2 ( ?5 tilt, ?5 twist and a high angle random boundary),as derived from atomistic calculations. All models are implemented in the MARMOT phase field code, which is used to calculate effective Xe and U diffusivities as well as redistribution for a few simple microstructures.

  14. Conversation View Outlook Web App User Guide

    E-Print Network [OSTI]

    Calgary, University of

    Conversation View Outlook Web App User Guide Email conversations that include multiple replies and sent messages can be viewed simultaneously using Conversation View. In Exchange 2010 Outlook Web App

  15. In-Situ Characterization of Cloud Condensation Nuclei, Interstitial, and background Particles using Single Particle Mass Spectrometer, SPLAT II

    SciTech Connect (OSTI)

    Zelenyuk, Alla; Imre, D.; Earle, Michael; Easter, Richard C.; Korolev, Alexei; Leaitch, W. R.; Liu, Peter; Macdonald, A. M.; Ovchinnikov, Mikhail; Strapp, Walter

    2010-10-01

    Aerosol indirect effect remains the most uncertain aspect of climate change modeling because proper test requires knowledge of individual particles sizes and compositions with high spatial and temporal resolution. We present the first deployment of a single particle mass spectrometer (SPLAT II) that is operated in a dual data acquisition mode to measure all the required individual particle properties with sufficient temporal resolution to definitively resolve the aerosol-cloud interaction in this exemplary case. We measured particle number concentrations, asphericity, and individual particle size, composition, and density with better than 60 seconds resolution. SPLAT II measured particle number concentrations between 70 particles cm-3and 300 particles cm-3, an average particle density of 1.4 g cm-3. Found that most particles are composed of oxygenated organics, many of which are mixed with sulfates. Biomass burn particles some with sulfates were prevalent, particularly at higher altitudes, and processed sea-salt was observed over the ocean. Analysis of cloud residuals shows that with time cloud droplets acquire sulfate by the reaction of peroxide with SO2. Based on the particle mass spectra and densities we find that the compositions of cloud condensation nuclei are similar to those of background aerosol but, contain on average ~7% more sulfate, and do not include dust and metallic particles. A comparison between the size distributions of background, activated, and interstitial particles shows that while nearly none of the activated particles is smaller than 115 nm, more than 80% of interstitial particles are smaller than 115 nm. We conclude that for this cloud the most important difference between CCN and background aerosol is particle size although having more sulfate also helps.

  16. SU-E-T-507: Interfractional Variation of Fiducial Marker Position During HDR Brachytherapy with Cervical Interstitial Needle Template

    SciTech Connect (OSTI)

    Shen, S; Kim, R; Benhabib, S; Araujo, J; Burnett, L; Duan, J; Popple, R; Wu, X; Cardan, R; Brezovich, I [UniversityAlabama Birmingham, Birmingham, AL (United Kingdom)

    2014-06-01

    Purpose: HDR brachytherapy using interstitial needle template for cervical cancer is commonly delivered in 4-5 fractions. Routine verification of needle positions before each fraction is often based on radiographic imaging of implanted fiducial markers. The current study evaluated interfractional displacement of implanted fiducial markers using CT images. Methods: 9 sequential patients with cervical interstitial needle implants were evaluated. The superior and inferior borders of the target volumes were defined by fiducial markers in planning CT. The implant position was verified with kV orthogonal images before each fraction. A second CT was acquired prior 3rd fraction (one or 2 days post planning CT). Distances from inferior and superior fiducial markers to pubic symphysis plane (perpendicular to vaginal obtulator)were measured. Distance from needle tip of a reference needle (next to the inferior marker) to the pubic symphysis plane was also determined. The difference in fiducial marker distance or needle tip distance between planning CT and CT prior 3rd fraction were measured to assess markers migration and needle displacement. Results: The mean inferior marker displacement was 4.5 mm and ranged 0.9 to 11.3 mm. The mean superior marker displacement was 2.7 mm and ranged 0 to 10.4 mm. There was a good association between inferior and superior marker displacement (r=0.95). Mean averaged inferior and superior marker displacement was 3.3 mm and ranged from 0.1 to 10.9 mm, with a standard deviation of 3.2 mm. The mean needle displacement was 5.6 mm and ranged 0.2 to 15.6 mm. Needle displacements were reduced (p<0.05) after adjusting according to needle-to-fiducials distance. Conclusion: There were small fiducial marker displacements between HDR fractions. Our study suggests a target margin of 9.7 mm to cover interfractional marker displacements (in 95% cases) for pretreatment verification based on radiographic imaging.

  17. Proton beam therapy facility

    SciTech Connect (OSTI)

    Not Available

    1984-10-09

    It is proposed to build a regional outpatient medical clinic at the Fermi National Accelerator Laboratory (Fermilab), Batavia, Illinois, to exploit the unique therapeutic characteristics of high energy proton beams. The Fermilab location for a proton therapy facility (PTF) is being chosen for reasons ranging from lower total construction and operating costs and the availability of sophisticated technical support to a location with good access to patients from the Chicago area and from the entire nation. 9 refs., 4 figs., 26 tabs.

  18. Wide field of view telescope

    DOE Patents [OSTI]

    Ackermann, Mark R. (Albuquerque, NM); McGraw, John T. (Placitas, NM); Zimmer, Peter C. (Albuquerque, NM)

    2008-01-15

    A wide field of view telescope having two concave and two convex reflective surfaces, each with an aspheric surface contour, has a flat focal plane array. Each of the primary, secondary, tertiary, and quaternary reflective surfaces are rotationally symmetric about the optical axis. The combination of the reflective surfaces results in a wide field of view in the range of approximately 3.8.degree. to approximately 6.5.degree.. The length of the telescope along the optical axis is approximately equal to or less than the diameter of the largest of the reflective surfaces.

  19. Input a journal Viewing Journals

    E-Print Network [OSTI]

    Sussex, University of

    Journals Contents: Input a journal Viewing Journals Deleting a journal Entering jnl into different period Problems Input a journal 1 Login to Bluqube 2 Select 3 Enter relevant Doc type To select the number of journals you will processing & the total credit value 6 Click on 7 Enter brief description 8

  20. The Catalog View Feature dataset

    E-Print Network [OSTI]

    The Catalog View Feature dataset Hydrography Geometric network HYDRO_NET Polygon feature class defines by FIPS 103, next six digits is a randomly assigned sequential number unique within a CatalogingSeep FCode 485 Water IntakeOutflow Resolution Resolution FCode 48500 Water IntakeOutflow FCode 487 Waterfall

  1. View

    E-Print Network [OSTI]

    2006-02-28

    Feb 28, 2006 ... AMS 2000 Subject Classification: Primary: ... of free NSO solvers, a possible reason is the lack of a significant library of NSO test functions.

  2. Neutron capture therapies

    DOE Patents [OSTI]

    Yanch, Jacquelyn C. (Cambridge, MA); Shefer, Ruth E. (Newton, MA); Klinkowstein, Robert E. (Winchester, MA)

    1999-01-01

    In one embodiment there is provided an application of the .sup.10 B(n,.alpha.).sup.7 Li nuclear reaction or other neutron capture reactions for the treatment of rheumatoid arthritis. This application, called Boron Neutron Capture Synovectomy (BNCS), requires substantially altered demands on neutron beam design than for instance treatment of deep seated tumors. Considerations for neutron beam design for the treatment of arthritic joints via BNCS are provided for, and comparisons with the design requirements for Boron Neutron Capture Therapy (BNCT) of tumors are made. In addition, exemplary moderator/reflector assemblies are provided which produce intense, high-quality neutron beams based on (p,n) accelerator-based reactions. In another embodiment there is provided the use of deuteron-based charged particle reactions to be used as sources for epithermal or thermal neutron beams for neutron capture therapies. Many d,n reactions (e.g. using deuterium, tritium or beryllium targets) are very prolific at relatively low deuteron energies.

  3. Density functional theory study on the interstitial chemical shifts of main-group-element centered hexazirconium halide clusters; synthetic control of speciation in [(Zr6ZCl12)] (Z = B, C)-based mixed ligand complexes 

    E-Print Network [OSTI]

    Shen, Jingyi

    2005-08-29

    The correlation between NMR chemical shifts of interstitial atoms and electronic structures of boron- and carbon-centered hexazirconium halide clusters was investigated by density functional theory (DFT) calculation. The ...

  4. Views of the solar system

    SciTech Connect (OSTI)

    Hamilton, C.

    1995-02-01

    Views of the Solar System has been created as an educational tour of the solar system. It contains images and information about the Sun, planets, moons, asteroids and comets found within the solar system. The image processing for many of the images was done by the author. This tour uses hypertext to allow space travel by simply clicking on a desired planet. This causes information and images about the planet to appear on screen. While on a planet page, hyperlinks travel to pages about the moons and other relevant available resources. Unusual terms are linked to and defined in the Glossary page. Statistical information of the planets and satellites can be browsed through lists sorted by name, radius and distance. History of Space Exploration contains information about rocket history, early astronauts, space missions, spacecraft and detailed chronology tables of space exploration. The Table of Contents page has links to all of the various pages within Views Of the Solar System.

  5. Views of wireless network systems.

    SciTech Connect (OSTI)

    Young, William Frederick; Duggan, David Patrick

    2003-10-01

    Wireless networking is becoming a common element of industrial, corporate, and home networks. Commercial wireless network systems have become reliable, while the cost of these solutions has become more affordable than equivalent wired network solutions. The security risks of wireless systems are higher than wired and have not been studied in depth. This report starts to bring together information on wireless architectures and their connection to wired networks. We detail information contained on the many different views of a wireless network system. The method of using multiple views of a system to assist in the determination of vulnerabilities comes from the Information Design Assurance Red Team (IDART{trademark}) Methodology of system analysis developed at Sandia National Laboratories.

  6. For current viewing resistor loads

    DOE Patents [OSTI]

    Lyons, Gregory R. (Tijeras, NM); Hass, Jay B. (Lee's Summit, MO)

    2011-04-19

    The invention comprises a terminal unit for a flat cable comprising a BNC-PCB connector having a pin for electrically contacting one or more conducting elements of a flat cable, and a current viewing resistor having an opening through which the pin extends and having a resistor face that abuts a connector face of the BNC-PCB connector, wherein the device is a terminal unit for the flat cable.

  7. Therapist and Adolescent Behavior in Online Therapy 

    E-Print Network [OSTI]

    Cepeda, Lisa Marie

    2009-05-15

    and repeated opportunities (anticipate future communications) to exchange information and build relationships. To examine the extent to which the process of online therapy resembles face-to-face therapy, online therapy transcripts were examined through a...

  8. The Equal Weight View, Agreement, and Commutativity 

    E-Print Network [OSTI]

    Buckler, Rose

    2011-11-23

    This paper investigates Elga’s (2007) Equal Weight View (EWV) and its consequences when understood as a view requiring epistemic peers to ‘split the difference’ following disagreement. The traditional disagreement debate ...

  9. View from the Bridge | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    View from the Bridge View from the Bridge This presentation gives an overview of Caterpillar's R&D focus on advanced diesel engines and exhaust aftertreatment. deer08utley.pdf...

  10. California's Energy Future - The View to 2050

    E-Print Network [OSTI]

    2011-01-01

    Summit on America’s Energy Future (2008), http://www.natural gas. California’s Energy Future - The View to 2050supply California’ s Energy Future - The View to 2050 and

  11. TotalView Training 2015

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home RoomPreservationBio-Inspired Solar FuelTechnologyTel:FebruaryEIA's Today8Topo II: AnUsersTotalView

  12. ISSN 2167-5163 View Publications

    E-Print Network [OSTI]

    Waldschmidt, Michel

    ISSN 2167-5163 View Publications View Author/Related Publications View Reviews Refine Search Co: 180085 Earliest Indexed Publication: 1970 Total Publications: 176 Total Author/Related Publications: 189 Chen Publications (by number in area) Associative rings and algebras Dynamical systems and ergodic

  13. Anticoagulation Drug Therapy: A Review

    E-Print Network [OSTI]

    Harter, Katherine; Levine, Michael; Henderson, Sean O.

    2015-01-01

    et al. Anticoagulation Drug Therapy: A Review 15. NishijimaRandomized antiplatelet drugs. In: Goodman & Gilman’s The2008;24:2757-65. Cardiovasc Drugs. 2006;6:265-85. 34. Nordt

  14. In vivo photodynamic therapy using upconversion nanoparticles as remote-

    E-Print Network [OSTI]

    Chaudhuri, Sanjay

    destruction. Moreover, invasive interstitial PDT which involves percutaneous implantation of light emitting diode (LED) probes arranged in a cylinder tip to fit into a balloon catheter to illuminate tumors

  15. Better Buildings Network View | March 2015 | Department of Energy

    Energy Savers [EERE]

    Better Buildings Network View | March 2015 Better Buildings Network View | March 2015 The Better Buildings Network View monthly newsletter from the U.S. Department of Energy's...

  16. Quantum states and specific heat of low-density He gas adsorbed within the carbon nanotube interstitial channels: Band structure effects and potential dependence

    E-Print Network [OSTI]

    A. Siber; H. Buljan

    2002-09-13

    We calculate the energy-band structure of a He atom trapped within the interstitial channel between close-packed nanotubes within a bundle and its influence on the specific heat of the adsorbed gas. A robust prediction of our calculations is that the contribution of the low-density adsorbed gas to the specific heat of the nanotube material shows pronounced nonmonotonic variations with temperature. These variations are shown to be closely related to the band gaps in the adsorbate density of states.

  17. High Performance Builder Spotlight: Clifton View Homes

    SciTech Connect (OSTI)

    2011-01-01

    Clifton View Homes’s remodel of a 1962 rambler, on Whidbey Island in Washington State, cut energy costs by two-thirds.

  18. Recombination radius of a Frenkel pair and capture radius of a self-interstitial atom by vacancy clusters in bcc Fe

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Nakashima, Kenichi; Stoller, Roger E.; Xu, Haixuan

    2015-08-04

    The recombination radius of a Frenkel pair is a fundamental parameter for the object kinetic Monte Carlo (OKMC) and mean field rate theory (RT) methods that are used to investigate irradiation damage accumulation in neutron irradiated nuclear materials. The recombination radius in bcc Fe has been studied both experimentally and numerically, however there is no general consensus about its value. The detailed atomistic processes of recombination also remain uncertain. Values from 1:0a? to 3:3a? have been employed as a recombination radius in previous studies using OKMC and RT. The recombination process of a Frenkel pair is investigated at the atomicmore »level using the self-evolved atomistic kinetic Monte Carlo (SEAKMC) method in this paper. SEAKMC calculations reveal that a self-interstitial atom recombines with a vacancy in a spontaneous reaction from several nearby sites following characteristic pathways. The recombination radius of a Frenkel pair is estimated to be 2.26a? by taking the average of the recombination distances from 80 simulation cases. This value agrees well with the experimental estimate. In addition, we apply these procedures to the capture radius of a self-interstitial atom by a vacancy cluster. The capture radius is found to gradually increase with the size of the vacancy cluster. The fitting curve for the capture radius is obtained as a function of the number of vacancies in the cluster.« less

  19. Toto the Robot Figure 1. Toto, front view. Figure 2. Toto, rear view.

    E-Print Network [OSTI]

    Indiana University

    Toto the Robot Figure 1. Toto, front view. Figure 2. Toto, rear view. Toto the Robot was created so a robot, helps account for his lack of verbal charm. Second, some younger children may recognize in Toto

  20. MyRED Mobiles Student Views

    E-Print Network [OSTI]

    Farritor, Shane

    tap on Shopping Cart, then select term. Tap on Class Search to find courses to place in your shoppingMyRED Mobiles Student Views Mar 2014 Page 1 Login/Sign-in Enter your MyRED /TrueYou credentials. Tap on any Term bar to view a schedule for the selected term. Home Screen/Main Menu Class Schedule

  1. MyRED Mobile Student Views

    E-Print Network [OSTI]

    Tsymbal, Evgeny Y.

    tap on Shopping Cart, then select term. Tap on Class Search to find courses to place in your shoppingMyRED Mobile Student Views Mar 2014 Page 1 Login/Sign-in Enter your MyRED /TrueYou credentials. Tap on any Term bar to view a schedule for the selected term. Home Screen/Main Menu Class Schedule Screen Tap

  2. Cancer Therapy with Particle Beams

    E-Print Network [OSTI]

    Olszewski Jr., Edward A.

    Cancer Therapy with Particle Beams #12;· The potential to use high energy particle beams to treat many types of cancer has been known even before their creation. · The availability of these treatments to be used in medicine, specifically for the treatment of certain cancers. His paper was published when

  3. Groundwater Modeling in ArcView: by integrating ArcView, MODFLOW and

    E-Print Network [OSTI]

    Sengupta, Raja

    Groundwater Modeling in ArcView: by integrating ArcView, MODFLOW and MODPATH Abstract Modeling. This paper addresses groundwater modeling which is one of the many entities in environmental modeling in ArcView 3.2a. The objective was to create an integrated system where a user could do groundwater

  4. Tailoring couple therapy techniques to client needs 

    E-Print Network [OSTI]

    Hsueh, Annie C.

    2010-01-14

    Research illuminating which therapist techniques are used in care-as-usual couple therapy, and under what circumstances, can contribute to a fuller understanding of how therapy works. The overall goal of the present study was to better understand...

  5. Radiation Therapy Program Technical Standards Procedure

    E-Print Network [OSTI]

    MacMillan, Andrew

    Radiation Therapy Program Technical Standards Procedure Original Approval Date: October 27, 2014 of the Radiation Therapy Program. 1 #12;Radiation Therapy Program Technical Standards Procedure accurately observe, as well as competently and independently complete complex technical procedures in a reasonable amount

  6. STANFORD REDWOOD CITY INFUSION THERAPY CENTER

    E-Print Network [OSTI]

    Puglisi, Joseph

    STANFORD REDWOOD CITY INFUSION THERAPY CENTER Stanford Redwood City Infusion Therapy Center 450 that the new Stanford Redwood City Infusion Therapy Center opened on January 6, 2014. This new state previously received infusion treatments in the Infusion Treatment Area (ITA) at the Stanford Cancer Center

  7. Rank Quantization Mountain View, CA, USA

    E-Print Network [OSTI]

    Singh, Jaswinder Pal

    Rank Quantization Ravi Kumar Google Mountain View, CA, USA ravi.k53@gmail.com Ronny Lempel Yahoo and that copies bear this notice and the full citation on the first page. To copy otherwise, to republish, to post

  8. A Utility View of Energy Conservation 

    E-Print Network [OSTI]

    Grant, S. A.

    1979-01-01

    Energy conservation, as viewed by the utility companies, is of real concern due to the energy situation and recent national energy legislation. The conversion programs of the electric utilities, particularly those in the southwestern part of the U...

  9. California's Energy Future - The View to 2050

    E-Print Network [OSTI]

    2011-01-01

    View to 2050 Laser Fusion Energy a Potential Game Changerworld leader in laser fusion energy—a potential game changera Laser Inertial Fusion Energy (LIFE) power plant would be

  10. TotalView Parallel Debugger at NERSC

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The performance of the GUI can be greatly improved if used in conjunction with free NX software. The TotalView documentation web page is a good resource for learning more...

  11. JOBAID-VIEWING AN EMPLOYEE MATRIX (SUPERVISOR)

    Broader source: Energy.gov [DOE]

    The purpose of this job aid is to guide supervisor users through the step-by-step process of viewing an employee matrix within SuccessFactors Learning.

  12. Incorporating video into Google Mobile Street View

    E-Print Network [OSTI]

    Wright, Christina (Christina E.)

    2010-01-01

    Mobile Street View is a compelling application but suffers from significant latency problems, especially in limited bandwidth circumstances. Currently, the application uses static images to display street level information. ...

  13. A view-sequential 3D display

    E-Print Network [OSTI]

    Cossairt, Oliver S. (Oliver Strider), 1978-

    2003-01-01

    This thesis outlines the various techniques for creating electronic 3D displays and analyzes their commercial potential. The thesis argues for the use of view-sequential techniques in the design of 3D displays based on ...

  14. A common-view disciplined oscillator

    SciTech Connect (OSTI)

    Lombardi, Michael A.; Dahlen, Aaron P.

    2010-05-15

    This paper describes a common-view disciplined oscillator (CVDO) that locks to a reference time scale through the use of common-view global positioning system (GPS) satellite measurements. The CVDO employs a proportional-integral-derivative controller that obtains near real-time common-view GPS measurements from the internet and provides steering corrections to a local oscillator. A CVDO can be locked to any time scale that makes real-time common-view data available and can serve as a high-accuracy, self-calibrating frequency and time standard. Measurement results are presented where a CVDO is locked to UTC(NIST), the coordinated universal time scale maintained at the National Institute of Standards and Technology in Boulder, Colorado.

  15. PARTICLE IMAGE VELOCIMETRY MEASUREMENTS IN A REPRESENTATIVE GAS-COOLED PRISMATIC REACTOR CORE MODEL: FLOW IN THE COOLANT CHANNELS AND INTERSTITIAL BYPASS GAPS

    SciTech Connect (OSTI)

    Thomas E. Conder; Richard Skifton; Ralph Budwig

    2012-11-01

    Core bypass flow is one of the key issues with the prismatic Gas Turbine-Modular Helium Reactor, and it refers to the coolant that navigates through the interstitial, non-cooling passages between the graphite fuel blocks instead of traveling through the designated coolant channels. To determine the bypass flow, a double scale representative model was manufactured and installed in the Matched Index-of-Refraction flow facility; after which, stereo Particle Image Velocimetry (PIV) was employed to measure the flow field within. PIV images were analyzed to produce vector maps, and flow rates were calculated by numerically integrating over the velocity field. It was found that the bypass flow varied between 6.9-15.8% for channel Reynolds numbers of 1,746 and 4,618. The results were compared to computational fluid dynamic (CFD) pre-test simulations. When compared to these pretest calculations, the CFD analysis appeared to under predict the flow through the gap.

  16. A Prospective Longitudinal Clinical Trial Evaluating Quality of Life After Breast-Conserving Surgery and High-Dose-Rate Interstitial Brachytherapy for Early-Stage Breast Cancer

    SciTech Connect (OSTI)

    Garsa, Adam A.; Ferraro, Daniel J.; DeWees, Todd A.; Deshields, Teresa L.; Margenthaler, Julie A.; Cyr, Amy E.; Naughton, Michael; Aft, Rebecca; Gillanders, William E.; Eberlein, Timothy; Matesa, Melissa A.; Ochoa, Laura L.; Zoberi, Imran

    2013-12-01

    Purpose: To prospectively examine quality of life (QOL) of patients with early stage breast cancer treated with accelerated partial breast irradiation (APBI) using high-dose-rate (HDR) interstitial brachytherapy. Methods and Materials: Between March 2004 and December 2008, 151 patients with early stage breast cancer were enrolled in a phase 2 prospective clinical trial. Eligible patients included those with Tis-T2 tumors measuring ?3 cm excised with negative surgical margins and with no nodal involvement. Patients received 3.4 Gy twice daily to a total dose of 34 Gy. QOL was measured using European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30, version 3.0, and QLQ-BR23 questionnaires. The QLQ-C30 and QLQ-BR23 questionnaires were evaluated during pretreatment and then at 6 to 8 weeks, 3 to 4 months, 6 to 8 months, and 1 and 2 years after treatment. Results: The median follow-up was 55 months. Breast symptom scores remained stable in the months after treatment, and they significantly improved 6 to 8 months after treatment. Scores for emotional functioning, social functioning, and future perspective showed significant improvement 2 years after treatment. Symptomatic fat necrosis was associated with several changes in QOL, including increased pain, breast symptoms, systemic treatment side effects, dyspnea, and fatigue, as well as decreased role functioning, emotional functioning, and social functioning. Conclusions: HDR multicatheter interstitial brachytherapy was well tolerated, with no significant detrimental effect on measured QOL scales/items through 2 years of follow-up. Compared to pretreatment scores, there was improvement in breast symptoms, emotional functioning, social functioning, and future perspective 2 years after treatment.

  17. Dumping Dirty Diesels: The View From the Bridge | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Dumping Dirty Diesels: The View From the Bridge Dumping Dirty Diesels: The View From the Bridge 2005 Diesel Engine Emissions Reduction (DEER) Conference Presentations and Posters...

  18. Proton beam therapy control system

    DOE Patents [OSTI]

    Baumann, Michael A. (Riverside, CA); Beloussov, Alexandre V. (San Bernardino, CA); Bakir, Julide (Alta Loma, CA); Armon, Deganit (Longmeadow, MA); Olsen, Howard B. (Irvine, CA); Salem, Dana (Riverside, CA)

    2010-09-21

    A tiered communications architecture for managing network traffic in a distributed system. Communication between client or control computers and a plurality of hardware devices is administered by agent and monitor devices whose activities are coordinated to reduce the number of open channels or sockets. The communications architecture also improves the transparency and scalability of the distributed system by reducing network mapping dependence. The architecture is desirably implemented in a proton beam therapy system to provide flexible security policies which improve patent safety and facilitate system maintenance and development.

  19. Proton beam therapy control system

    DOE Patents [OSTI]

    Baumann, Michael A; Beloussov, Alexandre V; Bakir, Julide; Armon, Deganit; Olsen, Howard B; Salem, Dana

    2013-06-25

    A tiered communications architecture for managing network traffic in a distributed system. Communication between client or control computers and a plurality of hardware devices is administered by agent and monitor devices whose activities are coordinated to reduce the number of open channels or sockets. The communications architecture also improves the transparency and scalability of the distributed system by reducing network mapping dependence. The architecture is desirably implemented in a proton beam therapy system to provide flexible security policies which improve patent safety and facilitate system maintenance and development.

  20. Proton beam therapy control system

    DOE Patents [OSTI]

    Baumann, Michael A; Beloussov, Alexandre V; Bakir, Julide; Armon, Deganit; Olsen, Howard B; Salem, Dana

    2013-12-03

    A tiered communications architecture for managing network traffic in a distributed system. Communication between client or control computers and a plurality of hardware devices is administered by agent and monitor devices whose activities are coordinated to reduce the number of open channels or sockets. The communications architecture also improves the transparency and scalability of the distributed system by reducing network mapping dependence. The architecture is desirably implemented in a proton beam therapy system to provide flexible security policies which improve patent safety and facilitate system maintenance and development.

  1. Proton beam therapy control system

    DOE Patents [OSTI]

    Baumann, Michael A. (Riverside, CA); Beloussov, Alexandre V. (Bernardino, CA); Bakir, Julide (Alta Loma, CA); Armon, Deganit (Redlands, CA); Olsen, Howard B. (Colton, CA); Salem, Dana (Riverside, CA)

    2008-07-08

    A tiered communications architecture for managing network traffic in a distributed system. Communication between client or control computers and a plurality of hardware devices is administered by agent and monitor devices whose activities are coordinated to reduce the number of open channels or sockets. The communications architecture also improves the transparency and scalability of the distributed system by reducing network mapping dependence. The architecture is desirably implemented in a proton beam therapy system to provide flexible security policies which improve patent safety and facilitate system maintenance and development.

  2. Compact accelerator for medical therapy

    DOE Patents [OSTI]

    Caporaso, George J.; Chen, Yu-Jiuan; Hawkins, Steven A.; Sampayan, Stephen E.; Paul, Arthur C.

    2010-05-04

    A compact accelerator system having an integrated particle generator-linear accelerator with a compact, small-scale construction capable of producing an energetic (.about.70-250 MeV) proton beam or other nuclei and transporting the beam direction to a medical therapy patient without the need for bending magnets or other hardware often required for remote beam transport. The integrated particle generator-accelerator is actuable as a unitary body on a support structure to enable scanning of a particle beam by direction actuation of the particle generator-accelerator.

  3. Dynamics of vascular normalization during anti-angiogenic therapy : implications for combination therapy

    E-Print Network [OSTI]

    Tong, Ricky T. (Ricky Tsee-Wai)

    2005-01-01

    Solid tumors require blood vessels for growth, and the goal of anti-angiogenic therapy is to destroy the tumor vasculature. Recent findings suggest that anti-angiogenic therapy enhances radiation and chemotherapy responses. ...

  4. Measurements using tangentially viewing bolometers on TFTR

    SciTech Connect (OSTI)

    Bush, C.E.; Schivell, J.; Budny, R.; Ellis R.A. III; Goldston, R.J.; McCune, D.; Medley, S.S.; Scott, S.D.; Towner, H.H.; Wieland, R.M.; and others

    1988-08-01

    Co- and counter-viewing bolometers aimed along a common tangency chord are being used to study power losses due to charge exchange (CX) of fast ions in neutral beam injection (NBI) heated TFTR plasmas. For unidirectional injection, tangential bolometers oriented to view CX loss of circulating fast ions detect losses from the thermal target plasma (impurity radiation and CX) plus power due to the fast ion CX loss, whereas bolometers oppositely directed measure only the target plasma contribution. The difference between the two signals is a measure of the fast ion CX loss. Additional information is obtained by comparing the tangential bolometer signals with those of perpendicularly viewing bolometer monitors and arrays. The measurements are compared to results of the TRANSP code analysis.

  5. Fields of View for Environmental Radioactivity

    E-Print Network [OSTI]

    Malins, Alex; Machida, Masahiko; Takemiya, Hiroshi; Saito, Kimiaki

    2015-01-01

    The gamma component of air radiation dose rates is a function of the amount and spread of radioactive nuclides in the environment. These radionuclides can be natural or anthropogenic in origin. The field of view describes the area of radionuclides on, or below, the ground that is responsible for determining the air dose rate, and hence correspondingly the external radiation exposure. This work describes Monte Carlo radiation transport calculations for the field of view under a variety of situations. Presented first are results for natural 40K and thorium and uranium series radionuclides distributed homogeneously within the ground. Results are then described for atmospheric radioactive caesium fallout, such as from the Fukushima Daiichi Nuclear Power Plant accident. Various stages of fallout evolution are considered through the depth distribution of 134Cs and 137Cs in soil. The fields of view for the natural radionuclides and radiocaesium are different. This can affect the responses of radiation monitors to th...

  6. Continuing Physical Therapy Education School of Physical Therapy, College of Medicine

    E-Print Network [OSTI]

    Saskatchewan, University of

    Continuing Physical Therapy Education School of Physical Therapy, College of Medicine Presents: Conference Fund & College of Medicine Visiting Lecture Fund Visiting Lecture Fund #12;CONFERENCE OVERVIEW of Physical Therapy in the College of Medicine at the University of Saskatchewan. Alumni from across

  7. BLUE VIEW VISION INSIGHT! Good news--your vision plan

    E-Print Network [OSTI]

    Mease, Kenneth D.

    WELCOME TO BLUE VIEW VISION INSIGHT! Good news--your vision plan is flexible and easy to use, your discounts, and much more! Blue View VisionSM Insight University of California Student Health Insurance Plan (UC SHIP) 2014/15 Your Blue View Vision Insight network Blue View Vision Insight offers you

  8. BLUE VIEW VISION INSIGHT! Good news--your vision plan

    E-Print Network [OSTI]

    Barrett, Jeffrey A.

    WELCOME TO BLUE VIEW VISION INSIGHT! Good news--your vision plan is flexible and easy to use, your discounts, and much more! Blue View Vision InsightSM University of California Student Health Insurance Plan (UC SHIP) 2012/13 Your Blue View Vision Insight Network Blue View Vision Insight offers you

  9. BLUE VIEW VISION INSIGHT! Good news--your vision plan

    E-Print Network [OSTI]

    California at Santa Cruz, University of

    WELCOME TO BLUE VIEW VISION INSIGHT! Good news--your vision plan is flexible and easy to use, your discounts, and much more! Blue View Vision InsightSM University of California Student Health Insurance Plan (UC SHIP) 2013/14 Your Blue View Vision Insight Network Blue View Vision Insight offers you

  10. Validation of mathematical models for the prediction of organs-at-risk dosimetric metrics in high-dose-rate gynecologic interstitial brachytherapy

    SciTech Connect (OSTI)

    Damato, Antonio L.; Viswanathan, Akila N.; Cormack, Robert A. [Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, Massachusetts 02115 (United States)] [Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, Massachusetts 02115 (United States)

    2013-10-15

    Purpose: Given the complicated nature of an interstitial gynecologic brachytherapy treatment plan, the use of a quantitative tool to evaluate the quality of the achieved metrics compared to clinical practice would be advantageous. For this purpose, predictive mathematical models to predict the D{sub 2cc} of rectum and bladder in interstitial gynecologic brachytherapy are discussed and validated.Methods: Previous plans were used to establish the relationship between D2cc and the overlapping volume of the organ at risk with the targeted area (C0) or a 1-cm expansion of the target area (C1). Three mathematical models were evaluated: D{sub 2cc}=?*C{sub 1}+? (LIN); D{sub 2cc}=?– exp(–?*C{sub 0}) (EXP); and a mixed approach (MIX), where both C{sub 0} and C{sub 1} were inputs of the model. The parameters of the models were optimized on a training set of patient data, and the predictive error of each model (predicted D{sub 2cc}? real D{sub 2cc}) was calculated on a validation set of patient data. The data of 20 patients were used to perform a K-fold cross validation analysis, with K = 2, 4, 6, 8, 10, and 20.Results: MIX was associated with the smallest mean prediction error <6.4% for an 18-patient training set; LIN had an error <8.5%; EXP had an error <8.3%. Best case scenario analysis shows that an error ?5% can be achieved for a ten-patient training set with MIX, an error ?7.4% for LIN, and an error ?6.9% for EXP. The error decreases with the increase in training set size, with the most marked decrease observed for MIX.Conclusions: The MIX model can predict the D{sub 2cc} of the organs at risk with an error lower than 5% with a training set of ten patients or greater. The model can be used in the development of quality assurance tools to identify treatment plans with suboptimal sparing of the organs at risk. It can also be used to improve preplanning and in the development of real-time intraoperative planning tools.

  11. Corroborating Information from Disagreeing Views Alban Galland

    E-Print Network [OSTI]

    Doyen, Laurent

    variety of information and viewpoints from individual Web sources that have different degree sources, many sources will continue to list outdated information if a person has switched jobsCorroborating Information from Disagreeing Views Alban Galland INRIA Saclay ­ Île-de-France LSV ENS

  12. A VIEW OF MATHEMATICS Alain CONNES

    E-Print Network [OSTI]

    Connes, Alain

    A VIEW OF MATHEMATICS Alain CONNES Mathematics is the backbone of modern science and a remarkably e#cient source of new concepts and tools to understand the ``reality'' in which we participate. It plays a basic role in the great new theories of physics of the XXth century such as general relativity, and quantum

  13. Longer View The Road Less Driven

    E-Print Network [OSTI]

    Handy, Susan L.

    Longer View The Road Less Driven Susan Handy I n September 2005, Hurricane Katrina slammed into New.S. Department of Energy [DOE], 2005a), a level unseen in inflation-adjusted terms even at the peak of the late 1970s energy crisis (DOE, 2005b). Shortages in the gasoline supply occurred temporarily in many parts

  14. Accelerated Volumetric Reconstruction From Uncalibrated Camera Views

    E-Print Network [OSTI]

    Whelan, Paul F.

    Accelerated Volumetric Reconstruction From Uncalibrated Camera Views Felicia Brisc, M.S. Ph. D-calibration 11 2.1.2 Bundle Adjustment 13 2.2 Volumetric Reconstruction ................................................. 14 2.2.1 Volumetric Intersection ........................................... 15 2.2.2 Voxel Carving

  15. A Survey of Hadron Therapy Accelerator Technologies.

    SciTech Connect (OSTI)

    PEGGS,S.; SATOGATA, T.; FLANZ, J.

    2007-06-25

    Hadron therapy has entered a new age [1]. The number of facilities grows steadily, and 'consumer' interest is high. Some groups are working on new accelerator technology, while others optimize existing designs by reducing capital and operating costs, and improving performance. This paper surveys the current requirements and directions in accelerator technology for hadron therapy.

  16. Method for microbeam radiation therapy

    DOE Patents [OSTI]

    Slatkin, D.N.; Dilmanian, F.A.; Spanne, P.O.

    1994-08-16

    A method is disclosed of performing radiation therapy on a patient, involving exposing a target, usually a tumor, to a therapeutic dose of high energy electromagnetic radiation, preferably X-ray radiation. The dose is in the form of at least two non-overlapping microbeams of radiation, each microbeam having a width of less than about 1 millimeter. Target tissue exposed to the microbeams receives a radiation dose during the exposure that exceeds the maximum dose that such tissue can survive. Non-target tissue between the microbeams receives a dose of radiation below the threshold amount of radiation that can be survived by the tissue, and thereby permits the non-target tissue to regenerate. The microbeams may be directed at the target from one direction, or from more than one direction in which case the microbeams overlap within the target tissue enhancing the lethal effect of the irradiation while sparing the surrounding healthy tissue. No Drawings

  17. Method for microbeam radiation therapy

    DOE Patents [OSTI]

    Slatkin, Daniel N. (Sound Beach, NY); Dilmanian, F. Avraham (Yaphank, NY); Spanne, Per O. (Shoreham, NY)

    1994-01-01

    A method of performing radiation therapy on a patient, involving exposing a target, usually a tumor, to a therapeutic dose of high energy electromagnetic radiation, preferably X-ray radiation, in the form of at least two non-overlapping microbeams of radiation, each microbeam having a width of less than about 1 millimeter. Target tissue exposed to the microbeams receives a radiation dose during the exposure that exceeds the maximum dose that such tissue can survive. Non-target tissue between the microbeams receives a dose of radiation below the threshold amount of radiation that can be survived by the tissue, and thereby permits the non-target tissue to regenerate. The microbeams may be directed at the target from one direction, or from more than one direction in which case the microbeams overlap within the target tissue enhancing the lethal effect of the irradiation while sparing the surrounding healthy tissue.

  18. Having trouble viewing this email? Click here to view online Engineering eNews

    E-Print Network [OSTI]

    Subramanian, Venkat

    of Service Award Nominations Due View More Events Research News Consortium for Clean Coal Utilization News Chancellor Mark S. Wrighton's announcement on the establishment of the Consortium for Clean Coal Utilization

  19. Having trouble viewing this email? Click here to view online Engineering eNews

    E-Print Network [OSTI]

    Subramanian, Venkat

    Washington University Research to Advance Clean Coal Technology The Consortium for Clean Coal Utilization to research clean coal technology, making St. Louis the nation's center for clean coal research. View Photos

  20. A View of the Cardiovascular Device Industry 

    E-Print Network [OSTI]

    Cisneros, Daniel Aaron

    2013-04-26

    -1 A VIEW OF THE CARDIOVASCULAR DEVICE INDUSTRY A Record of Study by DANIEL AARON CISNEROS Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements for the degree of DOCTOR... OF ENGINEERING Approved by: Chair of Committee, James E. Moore Committee Members, John C. Criscione Fred Clubb Richard H. Lester William Altman Andreas Gute Coordinator, College of Engineering, Robin Autenrieth May 2013 Major Subject...

  1. Lake View Geothermal Facility | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION J APPENDIXsource History ViewInformation

  2. Improving Targeted Radionuclide Therapy Using Nuclear Nanotechnology 

    E-Print Network [OSTI]

    Evans, Jordan Andrew

    2013-05-03

    The objectives of this thesis are to produce radioactive antibody-conjugated gold nanoparticles to improve the efficacy of targeted radionuclide therapy for the treatment of cancer, and to demonstrate that this product can be produced at Texas A...

  3. ALS Technique Gives Novel View of Lithium Battery Dendrite Growth

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ALS Technique Gives Novel View of Lithium Battery Dendrite Growth ALS Technique Gives Novel View of Lithium Battery Dendrite Growth Print Thursday, 24 April 2014 09:46 Lithium-ion...

  4. A DATABASE INTEGRATION SYSTEM BASED ON GLOBAL VIEW GENERATION

    E-Print Network [OSTI]

    Lawrence, Ramon

    A DATABASE INTEGRATION SYSTEM BASED ON GLOBAL VIEW GENERATION Uchang Park Duksung Women: database, integration, view, heterogeneity. Abstract: Database integration is a common and growing challenge with the proliferation of database systems, data warehouses, data marts, and other OLAP systems

  5. LabVIEW Core 2 Course | Jefferson Lab

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    LabVIEW Core 2 Course The Lab is advertising a LabVIEW Core 2 course coming to Newport News. Date: Next Thursday and Friday (716, 717) from 8 to 5 at the Canon facility location,...

  6. Cellulosic Biofuels: Expert Views on Prospects for Advancement: Supplementary Material

    E-Print Network [OSTI]

    Massachusetts at Amherst, University of

    Cellulosic Biofuels: Expert Views on Prospects for Advancement: Supplementary Material Erin Baker Keywords: Biofuels; Technology R&D; Uncertainty; Environmental policy 2 #12;1 Introduction This paper contains supplementary material for "Cellulosic Biofuels: Expert Views on Prospects for Advancement

  7. Radiation Therapy Program Technical Standards Self-Assessment and Details

    E-Print Network [OSTI]

    MacMillan, Andrew

    Radiation Therapy Program Technical Standards Self-Assessment and Details Original Approval Date Therapy Program (referred to as the "Program") Technical Standards Policy and Procedure, available of the Radiation Therapy Program. #12;Radiation Therapy Program Technical Standards Self-Assessment and Details 3

  8. Loop Quantum Gravity: An Inside View

    E-Print Network [OSTI]

    Thomas Thiemann

    2006-08-29

    This is a (relatively) non -- technical summary of the status of the quantum dynamics in Loop Quantum Gravity (LQG). We explain in detail the historical evolution of the subject and why the results obtained so far are non -- trivial. The present text can be viewed in part as a response to an article by Nicolai, Peeters and Zamaklar [hep-th/0501114]. We also explain why certain no go conclusions drawn from a mathematically correct calculation in a recent paper by Helling et al [hep-th/0409182] are physically incorrect.

  9. Energy Efficiency in Buildings- the Utilities View 

    E-Print Network [OSTI]

    Konig, U.

    2008-01-01

    Efficiency in Buildings - the Utilities View U. K?nig RWE Energy AG The energy to lead ESL-IC-08-10-27 Proceedings of the Eighth International Conference for Enhanced Building Operations, Berlin, Germany, October 20-22, 2008 RWE Energy... for Enhanced Building Operations, Berlin, Germany, October 20-22, 2008 RWE Energy / Energieeffizienz bei Immobilien / U. K?nig / ICEBO '08 SEITE 3 RWE ? One of the five leading Energy Companies in Europe > Nr 1 producer of electricity in Germany, Nr 3 in UK...

  10. Having trouble viewing this email? Click here to view online Engineering eNews

    E-Print Network [OSTI]

    Subramanian, Venkat

    Service Day Fri, Mar 12 Spring Break View More Events Research News Energy, Environmental & Chemical the National Aeronautics and Space Administration is for research titled "NASA and NAAPS Products for Air features ideas of Computer Science & Engineering faculty "It's increasingly difficult for the public

  11. Having trouble viewing this email? Click here to view online Meet the 2014 Alumni Achievement

    E-Print Network [OSTI]

    Subramanian, Venkat

    . READ MORE Plantbased plastics target of alumna Robertson's research Megan Robertson, PhD, who earned to petroleumbased plastics, or polymers. READ MORE March 915 Spring Break March 20 Alumni Achievement Awards Special Lecture VIEW MORE EVENTS the technology may help surgeons distinguish cancer cells, which glow in blue

  12. Having trouble viewing this email? Click here to view online Engineering eNews

    E-Print Network [OSTI]

    Subramanian, Venkat

    Chancellor Mark S. Wrighton says America has the potential to solve its energy crisis over the next decade this academic year. Read More U.S. energy future hinges on rapid rollout of emerging clean energy technologies Open Golf Tournament View More Events Research News Harvesting green energy Professor Himadri Pakrasi

  13. Having trouble viewing this email? Click here to view online JANUARY 2014

    E-Print Network [OSTI]

    Subramanian, Venkat

    .S.China Clean Energy Research CenterAdvanced Coal Technology Consortium to continue international progress in advanced coal technologies. VIEW MORE NEWS VIDEO: Blake Marggraff, president of WUTE (Washington University they use to their advantage. WUSTL joins U.S.China Clean Energy Research Center WUSTL joined the U

  14. Target Fabrication: A View from the Users

    SciTech Connect (OSTI)

    Kyrala, George A.; Balkey, Matthew M.; Barnes, Cris W.; Batha, Steven H.; Christensen, Cindy R.; Cobble, James A.; Fincke, James; Keiter, Paul; Lanier, Nicholas; Paisley, Dennis; Sorem, Michael; Swift, Damian; Workman, Jonathan

    2004-03-15

    Targets are used for a variety of purposes, but ultimately we use them to validate codes that help us predict and understand new phenomena or effects. The sophistication and complexity of High Energy Density Physics (HEDP) and Inertial Confinement Fusion (ICF) targets has increased in to match the advances made in modeling complex phenomena. The targets have changed from simple hohlraums, spherical geometries, and planar foils, to 3-dimensional geometries that require precision in construction, alignment, and metrology. Furthermore, material properties, such as surface morphologies and volume texture, have significant impact on the behavior of the targets and must be measured and controlled. In the following we will discuss how experimental physicists view targets and the influence that target construction has on interpreting the experimental results. We review a representative sampling of targets fabricated at the Los Alamos National Laboratory that are used in different experiments in support of ICF and HEDP.

  15. TARGET FABRICATION: A VIEW FROM THE USERS.

    SciTech Connect (OSTI)

    Kyrala, George A.; Balkey, Matthew M.; Batha, Steven H.; Barnes, Cris W.; Christensen, Cindy; Cobble, James; Fincke, James; Keiter, Paul; Lanier, Nicholas; Paisley, Dennis; Sorem, Michael S.; Swift, Damian; Workman, Jonathan

    2003-07-18

    Targets are used for a variety of purposes, but ultimately we use them to validate codes that help us predict and understand new phenomena or effects. The sophistication and complexity of High Energy Density Physics (HEDP) and Inertial Confinement Fusion (ICF) targets has increased in time to match the advances made in modeling complex phenomena. The targets have changed from simple hohlraums, spherical geometries, and planar foils, to 3-dimensional geometries that require precision in construction, alignment, and metrology. Furthermore, material properties, such as surface morphologies and volume texture, have significant impact on the behavior of the targets and must be measured and controlled. In the following we will discuss how experimental physicists view targets and the influence that target construction has on interpreting the experimental results. We review a representative sampling of targets fabricated at the Los Alamos National Laboratory that are used in different experiments in support of ICF and HEDP.

  16. Technical Design of Hadron Therapy Facilities

    SciTech Connect (OSTI)

    Alonso, J.R.

    1993-08-01

    Radiation therapy with hadron beams now has a 40-year track record at many accelerator laboratories around the world, essentially all of these originally physics-research oriented. The great promise shown for treating cancer has led the medical community to seek dedicated accelerator facilities in a hospital setting, where more rapid progress can be made in clinical research. This paper will discuss accelerator and beam characteristics relevant to hadron therapy, particularly as applied to hospital-based facilities. A survey of currently-operating and planned hadron therapy facilities will be given, with particular emphasis on Lorna Linda (the first dedicated proton facility in a hospital) and HIMAC (the first dedicated heavy-ion medical facility).

  17. Technical design of hadron therapy facilities

    SciTech Connect (OSTI)

    Alonso, J.R.

    1993-08-01

    Radiation therapy with hadron beams now has a 40-year track record at many accelerator laboratories around the world, essentially all of these originally physics-research oriented. The great promise shown for treating cancer has led the medical community to seek dedicated accelerator facilities in a hospital setting, where more rapid progress can be made in clinical research. This paper will discuss accelerator and beam characteristics relevant to hadron therapy, particularly as applied to hospital-based facilities. A survey of currently-operating and planned hadron therapy facilities will be given, with particular emphasis on Loma Linda (the first dedicated proton facility in a hospital) and HIMAC (the first dedicated heavy-ion medical facility).

  18. Teaching Evaluation Reports Available to Faculty Center and Operational Teaching Evaluations Report Users View Evaluation

    E-Print Network [OSTI]

    Cafarella, Michael J.

    Teaching Evaluation Reports Available to Faculty Center and Operational Teaching Evaluations Report Users View Evaluation Questions View Instructor Report View Instructor Report with Comments View, subjects and catalog numbers for the reports needed. 2008 Fall 1 Yes Yes email ro

  19. Java Therapy: Web-Based Robotic Rehabilitation

    E-Print Network [OSTI]

    Reinkensmeyer, David J.

    Java Therapy: Web-Based Robotic Rehabilitation David J. Reinkensmeyer, Clifton T. Pang, Jeff A performance, allowing users and their caregivers to assess rehabilitation progress via the Web. 1 are developing robotic devices, termed "rehabilitators", that physically interact with people to stimulate

  20. Porphyrins for boron neutron capture therapy

    DOE Patents [OSTI]

    Miura, Michiko (Center Moriches, NY); Gabel, Detlef (Bremen, DE)

    1990-01-01

    Novel compounds for treatment of brain tumors in Boron Neutron Capture Therapy are disclosed. A method for preparing the compounds as well as pharmaceutical compositions containing said compounds are also disclosed. The compounds are water soluble, non-toxic and non-labile boronated porphyrins which show significant uptake and retention in tumors.

  1. Durchbruch bei der Therapie der Hepatitis C

    E-Print Network [OSTI]

    Manstein, Dietmar J.

    Durchbruch bei der Therapie der Hepatitis C: Segen für die Patienten ­ Albtraum für die Behandler -Virushepatitis Oktober 2012 #12;H. Wedemeyer -Virushepatitis Oktober 2012 Hepatitisviren Hepatitis A Feinstone 1973 RNA Hepatitis B Blumberg 1965 DNA Hepatitis C Houghton 1988 RNA Hepatitis D Rizzetto 1977 RNA

  2. January 2013 Most Viewed Documents for Mathematics And Computing...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    January 2013 Most Viewed Documents for Mathematics And Computing Cybersecurity through Real-Time Distributed Control Systems Kisner, Roger A ORNL; Manges, Wayne W ORNL;...

  3. January 2013 Most Viewed Documents for Fission And Nuclear Technologie...

    Office of Scientific and Technical Information (OSTI)

    January 2013 Most Viewed Documents for Fission And Nuclear Technologies Laboratory studies of shearleach processing of zircaloy clad metallic uranium reactor fuel Swanson, J.L.;...

  4. January 2013 Most Viewed Documents for Power Generation And Distributi...

    Office of Scientific and Technical Information (OSTI)

    2013 Most Viewed Documents for Power Generation And Distribution Lessons from Large-Scale Renewable Energy Integration Studies: Preprint Bird, L.; Milligan, M. Small punch creep...

  5. September 2013 Most Viewed Documents for Renewable Energy Sources...

    Office of Scientific and Technical Information (OSTI)

    September 2013 Most Viewed Documents for Renewable Energy Sources Science Subject Feed Chapter 11. Heat Exchangers Rafferty, Kevin D.; Culver, Gene (1998) 362 > Wet cooling...

  6. April 2013 Most Viewed Documents for Renewable Energy Sources...

    Office of Scientific and Technical Information (OSTI)

    April 2013 Most Viewed Documents for Renewable Energy Sources Science Subject Feed Chapter 11. Heat Exchangers Rafferty, Kevin D.; Culver, Gene (1998) 1252 > Seventh Edition Fuel...

  7. June 2014 Most Viewed Documents for Renewable Energy Sources...

    Office of Scientific and Technical Information (OSTI)

    June 2014 Most Viewed Documents for Renewable Energy Sources Science Subject Feed Chapter 6. Drilling and Well Construction Culver, Gene (1998) 426 > Chapter 11. Heat Exchangers...

  8. New ALS Technique Gives Nanoscale Views of Complex Systems

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Nanoscale Views of Complex Systems Print Studying and identifying molecules at the mesoscale has always been challenging-even the best microscopes and spectrometers have...

  9. The Better Buildings Neighborhood View -- December 2013 | Department...

    Broader source: Energy.gov (indexed) [DOE]

    & Publications The Better Buildings Neighborhood View -- July 2013 Focus Series: Philadelphia Energyworks: In the City of Brotherly Love, Sharing Know-How Leads to...

  10. Tracing Technologies: Prisoners' Views in the Era of CSI

    E-Print Network [OSTI]

    Cole, SA

    2013-01-01

    Tracing Technologies: Prisoners’ Views in the Era of CSI.Studies, they argue that prisoners have ‘professionalinterview study of Austrian prisoners. The study design was

  11. April 2013 Most Viewed Documents for Biology And Medicine | OSTI...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    April 2013 Most Viewed Documents for Biology And Medicine Science Subject Feed Publications in biomedical and environmental sciences programs, 1981 Moody, J.B. (comp.) (1982) 306...

  12. March 2014 Most Viewed Documents for Biology And Medicine | OSTI...

    Office of Scientific and Technical Information (OSTI)

    4 Most Viewed Documents for Biology And Medicine Science Subject Feed Carbon Dioxide Sequestering Using Microalgal Systems Daniel J. Stepan; Richard E. Shockey; Thomas A. Moe; Ryan...

  13. September 2015 Most Viewed Documents for Biology And Medicine...

    Office of Scientific and Technical Information (OSTI)

    September 2015 Most Viewed Documents for Biology And Medicine Measuring dopamine release in the human brain with PET Volkow, N.D. Brookhaven National Lab., Upton, NY (United...

  14. July 2013 Most Viewed Documents for Biology And Medicine | OSTI...

    Office of Scientific and Technical Information (OSTI)

    July 2013 Most Viewed Documents for Biology And Medicine Science Subject Feed Carbon Dioxide Sequestering Using Microalgal Systems Daniel J. Stepan; Richard E. Shockey; Thomas A....

  15. September 2013 Most Viewed Documents for Biology And Medicine...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    September 2013 Most Viewed Documents for Biology And Medicine Science Subject Feed Drug Retention Times Center for Human Reliability Studies (2007) 29 > Oleoresin Capsicum...

  16. June 2015 Most Viewed Documents for Biology And Medicine | OSTI...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    June 2015 Most Viewed Documents for Biology And Medicine Measuring dopamine release in the human brain with PET Volkow, N.D. Brookhaven National Lab., Upton, NY (United...

  17. BetterBuildings Network View | January 9, 2014

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    View kicks off 2014, meet the 14 freshest faces to join the Residential Network: BC Hydro; California Energy Commission; District of Columbia Sustainable Energy Utility;...

  18. Better Buildings Network View | September 2014 | Department of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Publications Focus Series: OREGON-On Bill Financing Program: On-Bill Financing Brings Lenders and Homeowners On Board Better Buildings Network View | December 2014 On-Bill...

  19. Cell Death Pathways in Photodynamic Therapy of Cancer

    E-Print Network [OSTI]

    Mroz, Pawel

    Photodynamic therapy (PDT) is an emerging cancer therapy that uses the combination of non-toxic dyes or photosensitizers (PS) and harmless visible light to produce reactive oxygen species and destroy tumors. The PS can be ...

  20. Radiobiology of normal rat lung in Boron Neutron Capture Therapy

    E-Print Network [OSTI]

    Kiger, Jingli Liu

    2006-01-01

    Boron Neutron Capture Therapy (BNCT) is a binary cancer radiation therapy that utilizes biochemical tumor cell targeting and provides a mixed field of high and low Linear Energy Transfer (LET) radiation with differing ...

  1. Development of an interleukin 2 receptor targeted gene therapy vehicle 

    E-Print Network [OSTI]

    Wattanakaroon, Wanida

    2006-08-16

    The effectiveness of most chemotherapeutic regimens is limited by the toxicity of the therapy to normal healthy cells. Therapies to selectively modulate abnormal T cells bearing the interleukin 2 receptor (IL-2R) have been ...

  2. In-situ measurement of electrodermal activity during occupational therapy

    E-Print Network [OSTI]

    Hedman, Elliott B. (Elliot Bruce)

    2010-01-01

    Physiological arousal is an important part of occupational therapy for children with Sensory Processing Disorder (SPD) but therapists do not have a way to objectively measure how therapy affects arousal. We hypothesized ...

  3. Brachial Plexus-Associated Neuropathy After High-Dose Radiation Therapy for Head-and-Neck Cancer

    SciTech Connect (OSTI)

    Chen, Allen M.; Hall, William H.; Li, Judy; Beckett, Laurel; Farwell, D. Gregory; Lau, Derick H.; Purdy, James A.

    2012-09-01

    Purpose: To identify clinical and treatment-related predictors of brachial plexus-associated neuropathies after radiation therapy for head-and-neck cancer. Methods and Materials: Three hundred thirty patients who had previously completed radiation therapy for head-and-neck cancer were prospectively screened using a standardized instrument for symptoms of neuropathy thought to be related to brachial plexus injury. All patients were disease-free at the time of screening. The median time from completion of radiation therapy was 56 months (range, 6-135 months). One-hundred fifty-five patients (47%) were treated by definitive radiation therapy, and 175 (53%) were treated postoperatively. Radiation doses ranged from 50 to 74 Gy (median, 66 Gy). Intensity-modulated radiation therapy was used in 62% of cases, and 133 patients (40%) received concurrent chemotherapy. Results: Forty patients (12%) reported neuropathic symptoms, with the most common being ipsilateral pain (50%), numbness/tingling (40%), motor weakness, and/or muscle atrophy (25%). When patients with <5 years of follow-up were excluded, the rate of positive symptoms increased to 22%. On univariate analysis, the following factors were significantly associated with brachial plexus symptoms: prior neck dissection (p = 0.01), concurrent chemotherapy (p = 0.01), and radiation maximum dose (p < 0.001). Cox regression analysis confirmed that both neck dissection (p < 0.001) and radiation maximum dose (p < 0.001) were independently predictive of symptoms. Conclusion: The incidence of brachial plexus-associated neuropathies after radiation therapy for head-and-neck cancer may be underreported. In view of the dose-response relationship identified, limiting radiation dose to the brachial plexus should be considered when possible.

  4. IIIPRISMA System Operator's Manual PRISMA Therapy Options ............................................................................. 2

    E-Print Network [OSTI]

    Kay, Mark A.

    IIIPRISMA System Operator's Manual ... PRISMA Therapy Options .................................................................................................... PRISMA System ............................... xvi Operator's Manual ......................................................... #12;PRISMA System Operator's Manual ia Controller CCA

  5. Optimal Lipid Modification: the Rationale for Combination Therapy

    E-Print Network [OSTI]

    Backes, James M.; Gibson, Cheryl A.; Howard, Patricia A.

    2005-01-25

    , combination therapy has been shown to be advantageous in type 2 diabetes mellitus (DM) resulting in better glycemic control and fewer complications (Bell and Ovalle 2004; Strowig et al 2004). For patients with dyslipidemia, hesitancy to use combination therapy..., combination therapy has been shown to be advantageous in type 2 diabetes mellitus (DM) resulting in better glycemic control and fewer complications (Bell and Ovalle 2004; Strowig et al 2004). For patients with dyslipidemia, hesitancy to use combination therapy...

  6. Physical Therapy Career Options Human Biology Health & Society (HBHS)

    E-Print Network [OSTI]

    Chen, Tsuhan

    65 Physical Therapy Career Options Human Biology Health & Society (HBHS) Nutritional Sciences ­ CHE-CALS) ________________________________________________________________________________________ Many NS-CHE, NS-CALS and HBHS majors consider physical therapy as a career option because, performance and rehabilitation. The pathway to a career in physical therapy for Cornell undergraduates

  7. Radiation therapy of pediatric brain tumors : comparison of long-term health effects and costs between proton therapy and IMRT

    E-Print Network [OSTI]

    Vu, An T. (An Thien)

    2011-01-01

    Radiation therapy is an important component of pediatric brain tumor treatment. However, radiation-induced damage can lead to adverse long-term health effects. Proton therapy has the ability to reduce the dose delivered ...

  8. View and Perspective Beyond Neurovascular: Migraine as a Dysfunctional

    E-Print Network [OSTI]

    , the effi- cacy of behavioral therapies, and the often dramatic resolution of chronic migraine with a change © 2012 American Headache Society 1 #12;milieu. Brainstem sensitization explains much of the snapshot we

  9. The use of photodynamic therapy to treat hidradenitis suppurativa a review and critical analysis

    E-Print Network [OSTI]

    Scheinfeld, Noah

    2015-01-01

    T. Photodynamic therapy: off-label and alternative use inreal-life practice of off-label photodynamic therapy using

  10. Prairie View A&M University Whole Campus Energy Analysis 

    E-Print Network [OSTI]

    Haberl, J. S.; Claridge, D. E.; Turner, W. D.

    1991-01-01

    Prairie View A&M University started a large scale energy management program in 1987 and 1988. This report presents an analysis of whole-campus energy consumption at the Prairie View A&M Campus where whole-campus indices were developed that normalize...

  11. Materialized View Selection and Maintenance Using Multi-Query Optimization

    E-Print Network [OSTI]

    Ramamritham, Krithi

    Materialized View Selection and Maintenance Using Multi-Query Optimization Hoshi Mistry ¡ Prasan the differentials as above. Our work addresses the problem of optimizing the main- tenance of a set of materialized Materialized views have been found to be very effective at speeding up queries, and are increasingly being

  12. Page 1 of 10 World View, Metaphysics, and Epistemology

    E-Print Network [OSTI]

    Cobern, William W.

    concept. The recent discussion in science education about world view is essentially a discussion about Working Paper No. 106 William W. Cobern, Ph.D. Associate Professor of Science Education Arizona State from which the concept is taken. #12;Page 1 of 10 Abstract WORLD VIEW, METAPHYSICS, AND EPISTEMOLOGY

  13. O'Leary outlines policy views at confirmation hearing

    SciTech Connect (OSTI)

    Simpson, J.

    1993-02-15

    In her confirmation hearing, Secretary O'Leary outlined her views on various controversial issues. Among these were management of Yucca Mountain and the search for a nuclear waste repository, research on alternative fuels, encouragement of the use of renewable energy sources, and her views on intergrated resource planning.

  14. NEWS AND VIEWS Alternative splicing variability: exactly how similar

    E-Print Network [OSTI]

    Ares Jr., Manny

    NEWS AND VIEWS Alternative splicing variability: exactly how similar are two identical cells and provide the first direct view of alternative splicing at the single cell level. Early hints that alternative splicing might vary within an isogenic cell population came from studies using clever dual

  15. MAGNETIC RESONANCE IMAGE VIEWING ``SCREEN REAL ESTATE'' PROBLEM

    E-Print Network [OSTI]

    Atkins, M. Stella

    MAGNETIC RESONANCE IMAGE VIEWING AND THE ``SCREEN REAL ESTATE'' PROBLEM By Johanna van der Heyden B Degree: Master of Science Title of thesis: Magnetic Resonance Image Viewing and the ``Screen Real Estate. These ``screen real estate'' issues are extensively explored in the literature but not consistently applied

  16. View-Dependent Articulated-Body Simulation with Adaptive Forward

    E-Print Network [OSTI]

    View-Dependent Articulated-Body Simulation with Adaptive Forward Dynamics Daseong Han KAIST (Korea Advanced Institute of Science and Technology) #12;2 Outline Introduction Related Work Simulation Levels and Conquer Algorithm(DCA) For Forward Dynamics Adaptive Forward Dynamics(AFD) View-dependent Forward

  17. PAINTING LIGHTING AND VIEWING EFFECTS Cindy Grimm, Michael Kowalski

    E-Print Network [OSTI]

    Grimm, Cindy

    PAINTING LIGHTING AND VIEWING EFFECTS Cindy Grimm, Michael Kowalski Washington University in St-photorealistic rendering Abstract: We present a system for painting how the appearance of an object changes under different lighting and viewing conditions. The user paints what the object should look like under different lighting

  18. original article The American Society of Gene & Cell Therapy Molecular Therapy vol. 20 no. 4, 829839 apr. 2012 829

    E-Print Network [OSTI]

    Park, Jong-Sang

    original article© The American Society of Gene & Cell Therapy Molecular Therapy vol. 20 no. 4, 829 that the intranasal delivery of HMGB1 siRNA offers an efficient means of gene knockdown-mediated therapy is released by necrotic cells into the extracellular milieu and is also actively secreted by macrophages

  19. A Narrower Spectrum for a Wider View of Matter

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Wider View of Matter July 9, 2014 Bookmark and Share Ultra-high-resolution dispersive optics of the new inelastic x-ray scattering (IXS) spectrometer (top) and IXS spectrum of...

  20. Sensor planning for novel view generation by camera networks

    E-Print Network [OSTI]

    Barabas, James

    2006-01-01

    This document describes a system for generating novel views of an indoor visual scene by gathering successive 2D images from a set of independent networked robotic cameras. Specifically, the robotic cameras work to seek ...

  1. Plan-view Trajectory Estimation with Dense Stereo Background Models

    E-Print Network [OSTI]

    Darrell, T.

    2001-02-01

    In a known environment, objects may be tracked in multiple views using a set of back-ground models. Stereo-based models can be illumination-invariant, but often have undefined values which inevitably lead to foreground ...

  2. RELATIVISTIC ASTROPHYSICS - THE VIEW FROM TEXAS IN BALTIMORE - (REVIEW)

    E-Print Network [OSTI]

    TRIMBLE, V; MARAN, S

    1981-01-01

    The View from Texas in Baltimore (Review) V. L. TRIMBLEand, most recently, Baltimore (De- cember 15-19, 1980).even its sign) ~ TEXAS IN BALTIMORE f ·very sensitive to

  3. Countermeasures to Urban Heat Islands: A Global View

    E-Print Network [OSTI]

    Meier, Alan

    2006-01-01

    Countermeasures to Urban Heat Islands: A Global View Alanurban climate is the phenomenon of the urban heat island.The urban heat island phenomenon was first observed over one

  4. Development of AeroView: an interactive flow diagnostics laboratory 

    E-Print Network [OSTI]

    Galls, Samuel Fernando

    1996-01-01

    This research includes the development of a set of experimental flow-diagnostics techniques for low speed aerodynamics applications and an interactive software for flow field data acquisition and presentation called AeroView. The data collection...

  5. Host nutrition and infectious disease: an ecological view

    E-Print Network [OSTI]

    Smith, Val H.; Jones II, Tyrees P.; Smith, Marilyn S.

    2005-06-01

    Nutrition is typically discussed in terms of maintaining a proper diet and avoiding nutrient deficiency diseases. However, nutrition can also be viewed from an ecological standpoint: mammalian hosts and their pathogens ...

  6. A Transformational View of Cartography W. R. Tobler

    E-Print Network [OSTI]

    Clarke, Keith

    A Transformational View of Cartography W. R. Tobler ABSTRACT. Cartographic transformations aliases are between points, lines, and areas. Substantive transformations occur in map interpolation transformational grammars, as originally devised for linguistics.2, 4 A similar, though less ambitious, attempt

  7. April 2013 Most Viewed Documents for Fission And Nuclear Technologies...

    Office of Scientific and Technical Information (OSTI)

    April 2013 Most Viewed Documents for Fission And Nuclear Technologies Science Subject Feed Behavior of spent nuclear fuel in water pool storage Johnson, A.B. Jr. (null) 298 >...

  8. June 2015 Most Viewed Documents for Fission And Nuclear Technologies...

    Office of Scientific and Technical Information (OSTI)

    June 2015 Most Viewed Documents for Fission And Nuclear Technologies Estimation of gas leak rates through very small orifices and channels. From sealed PuOsub 2 containers under...

  9. March 2015 Most Viewed Documents for Biology And Medicine | OSTI...

    Office of Scientific and Technical Information (OSTI)

    5 Most Viewed Documents for Biology And Medicine Measuring dopamine release in the human brain with PET Volkow, N.D. Brookhaven National Lab., Upton, NY (United States)|State...

  10. June 2014 Most Viewed Documents for Biology And Medicine | OSTI...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    June 2014 Most Viewed Documents for Biology And Medicine Science Subject Feed Modification to the Monte Carlo N-Particle (MCNP) Visual Editor (MCNPVised) to Read in Computer Aided...

  11. GoddardView National Aeronautics and Space Administration

    E-Print Network [OSTI]

    Christian, Eric

    GoddardView National Aeronautics and Space Administration www.nasa.gov Volume 3 Issue 9 July 2007 On Pg 11 National Aeronautics and Space Administration www.nasa.gov Volume 3 Issue 9 July 2007 LRO

  12. GoddardView National Aeronautics and Space Administration

    E-Print Network [OSTI]

    Christian, Eric

    GoddardView National Aeronautics and Space Administration www.nasa.gov Volume 3 Issue 8 June 2007 Commemorative Issue Royal Visit 2007: Her Majesty Queen Elizabeth II May 8, 2007 National Aeronautics and Space

  13. Acceleration Of Wound Healing Ny Photodynamic Therapy

    DOE Patents [OSTI]

    Hasan, Tayyaba (Arlington, MA); Hamblin, Michael R. (Revere, MA); Trauner, Kenneth (Sacramento, CA)

    2000-08-22

    Disclosed is a method for accelerating wound healing in a mammal. The method includes identifying an unhealed wound site or partially-healed wound site in a mammal; administering a photosensitizer to the mammal; waiting for a time period wherein the photosensitizer reaches an effective tissue concentration at the wound site; and photoactivating the photosensitizer at the wound site. The dose of photodynamic therapy is selected to stimulate the production of one or more growth factor by cells at the wound site, without causing tissue destruction.

  14. Gantry for medical particle therapy facility

    DOE Patents [OSTI]

    Trbojevic, Dejan (Wading River, NY)

    2012-05-08

    A particle therapy gantry for delivering a particle beam to a patient includes a beam tube having a curvature defining a particle beam path and a plurality of fixed field magnets sequentially arranged along the beam tube for guiding the particle beam along the particle path. In a method for delivering a particle beam to a patient through a gantry, a particle beam is guided by a plurality of fixed field magnets sequentially arranged along a beam tube of the gantry and the beam is alternately focused and defocused with alternately arranged focusing and defocusing fixed field magnets.

  15. Gantry for medical particle therapy facility

    DOE Patents [OSTI]

    Trbojevic, Dejan

    2013-04-23

    A particle therapy gantry for delivering a particle beam to a patient includes a beam tube having a curvature defining a particle beam path and a plurality of superconducting, variable field magnets sequentially arranged along the beam tube for guiding the particle beam along the particle path. In a method for delivering a particle beam to a patient through a gantry, a particle beam is guided by a plurality of variable field magnets sequentially arranged along a beam tube of the gantry and the beam is alternately focused and defocused with alternately arranged focusing and defocusing variable field magnets.

  16. Metalloporphyrins and their uses as radiosensitizers for radiation therapy

    DOE Patents [OSTI]

    Miura, Michiko; Slatkin, Daniel N.

    2004-07-06

    The present invention covers radiosensitizers containing as an active ingredient halogenated derivatives of boronated porphyrins containing multiple carborane cages having the structure ##STR1## which selectively accumulate in neoplastic tissue within the irradiation volume and thus can be used in cancer therapies including, but not limited to, boron neutron--capture therapy and photodynamic therapy. The present invention also covers methods for using these radiosensitizers in tumor imaging and cancer treatment.

  17. Radioisotopes for Medical Diagnostics and Cancer Therapy at BNL...

    Office of Science (SC) Website

    Radioisotopes for Medical Diagnostics and Cancer Therapy at BNL Nuclear Physics (NP) NP Home About Research Facilities Science Highlights Benefits of NP Applications of Nuclear...

  18. Occupational therapy is a healthcare profession that provides services to

    E-Print Network [OSTI]

    Sibille, Etienne

    Occupational therapy is a healthcare profession that provides services to individuals of all ages of occupational therapy services, and contributor to the profession. The occupational therapist practitioner and healthcare, participates in clinical research, and advocates appropriately for clients and the profession

  19. Intraoperative radiation therapy in recurrent ovarian cancer

    SciTech Connect (OSTI)

    Yap, O.W. Stephanie . E-mail: stbeast@stanford.edu; Kapp, Daniel S.; Teng, Nelson N.H.; Husain, Amreen

    2005-11-15

    Purpose: To evaluate disease outcomes and complications in patients with recurrent ovarian cancer treated with cytoreductive surgery and intraoperative radiation therapy (IORT). Methods and Materials: A retrospective study of 24 consecutive patients with ovarian carcinoma who underwent secondary cytoreduction and intraoperative radiation therapy at our institution between 1994 and 2002 was conducted. After optimal cytoreductive surgery, IORT was delivered with orthovoltage X-rays (200 kVp) using individually sized and beveled cone applications. Outcomes measures were local control of disease, progression-free interval, overall survival, and treatment-related complications. Results: Of these 24 patients, 22 were available for follow-up analysis. Additional treatment at the time of and after IORT included whole abdominopelvic radiation, 9; pelvic or locoregional radiation, 5; chemotherapy, 6; and no adjuvant treatment, 2. IORT doses ranged from 9-14 Gy (median, 12 Gy). The anatomic sites treated were pelvis (sidewalls, vaginal cuff, presacral area, anterior pubis), para-aortic and paracaval lymph node beds, inguinal region, or porta hepatitis. At a median follow-up of 24 months, 5 patients remain free of disease, whereas 17 patients have recurred, of whom 4 are alive with disease and 13 died from disease. Five patients recurred within the radiation fields for a locoregional relapse rate of 32% and 12 patients recurred at distant sites with a median time to recurrence of 13.7 months. Five-year overall survival was 22% with a median survival of 26 months from time of IORT. Nine patients (41%) experienced Grade 3 toxicities from their treatments. Conclusion: In carefully selected patients with locally recurrent ovarian cancer, combined IORT and tumor reductive surgery is reasonably tolerated and may contribute to achieving local control and disease palliation.

  20. War, Trauma, and Technologies of the Self : : The Making of Virtual Reality Exposure Therapy

    E-Print Network [OSTI]

    Brandt, Marisa Renee

    Therapy Require Technological Enhancement? Virtual Iraq’s Therapeutic Milieu ..Therapy Require Technological Enhancement? Virtual Iraq’s Therapeutic Milieumilieu they saw their work as part of: which was shaped more by experience in entertainment media than in therapy.

  1. How can I view submitted materials? | OpenEI Community

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QAsource History View NewTexas: Energy Resources JumpNew Jersey:Hopkinsville,Advanced ResearchHow can I view

  2. Mountain View, Colorado: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QAsource History ViewMayo, Maryland: EnergyInformationOliver, Pennsylvania: EnergyPark, Georgia:View, Colorado:

  3. Prairie View Gas Recovery Biomass Facility | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QAsource History ViewMayo, Maryland:NPIProtectio1975) |Texas:PottawattamiePowerSatMontana: EnergyView Gas Recovery

  4. Highland View school | Y-12 National Security Complex

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverse (JournalvivoHigh energyHighland View school Highland View school Aerial

  5. General Information for Physical Therapy School: Prerequisites for admission to physical therapy school exhibit extreme variation between

    E-Print Network [OSTI]

    Walker, Lawrence R.

    General Information for Physical Therapy School: Prerequisites for admission to physical therapy Chemistry I and II (CHEM 121/121L, CHEM 122/122L) - General Physics I and II (PHYS 151/151L, PHYS 152, 152L, it is not possible to recommend a uniform curriculum that prepares the student for application to all physical

  6. Installing and Using VMWare View Client for Android This document describes how to get up and running with View if your device runs an Android

    E-Print Network [OSTI]

    Neirotti, Juan Pablo

    1 Installing and Using VMWare View Client for Android This document describes how to get up and running with View if your device runs an Android operating system. Instructions may differ slightly from

  7. Sea Oil Field Satellite Monitoring: An Opera3onal View

    E-Print Network [OSTI]

    Kuligowski, Bob

    :on alone contains 54% of the sea's oil reserves and 45% of its gasSea Oil Field Satellite Monitoring: An Opera3onal View Maurizio, Camp Springs, MD 20746 #12;Outline Introduc:on Sea oil fields Synthe:c Aperture

  8. www.advmat.de www.MaterialsViews.com

    E-Print Network [OSTI]

    Hong, Soon Hyung

    by plasma- enhanced chemical vapor deposition. Methane (CH4) was used as the carbon source to synthesize. The strong protein-based adhesives found in marine mussel Mytilus edulis, provide an important insight for the solidification by oxidative chemical crosslinking.[21­24] From a chemical point of view, covalent crosslinking

  9. Analytic Verification at NASA A View from the Trenches

    E-Print Network [OSTI]

    Jipsen, Peter

    Analytic Verification at NASA A View from the Trenches Willem C. Visser July 31, 1999 Autonomous software is considered a major enabling technology for NASA in order to achieve the goal of their slogan Software Engineering 2 (ASE) group at NASA Ames Research Center is developing analytic verification

  10. Formal Methods Technology Transfer: A View from NASA

    E-Print Network [OSTI]

    Caldwell, James

    Formal Methods Technology Transfer: A View from NASA James L. Caldwell Flight Electronics Technology Division NASA Langley Research Center Hampton, Virginia 23681 26 February 1996 Abstract Since 1988 NASA Langley Research Center has supported a formal methods research group. From its inception

  11. A View Based Survey on Web services Registries

    E-Print Network [OSTI]

    Dustdar, Schahram

    A View Based Survey on Web services Registries Schahram Dustdar and Martin Treiber dustdar Information Systems Institute Distributed Systems Group Web services registries are a cornerstone for the emerging service-oriented architecture and constitute a critical resource for Web services. Based on a case

  12. Shape Anchors for Data-Driven Multi-view Reconstruction

    E-Print Network [OSTI]

    Xiao, Jianxiong

    We present a data-driven method for building dense 3D reconstructions using a combination of recognition and multi-view cues. Our approach is based on the idea that there are image patches that are so distinctive that we ...

  13. Efficient Integrity Checking for Databases with Recursive Views

    E-Print Network [OSTI]

    Martinenghi, Davide

    Efficient Integrity Checking for Databases with Recursive Views Davide Martinenghi and Henning Christiansen Roskilde University, Computer Science Dept. P.O.Box 260, DK-4000 Roskilde, Denmark E-mail: {dm,henning-finding problems, such as network routing and travel planning. The introduction of re- cursion (since 1999

  14. Comparing Genomes with Duplications: A Computational Complexity Point of View

    E-Print Network [OSTI]

    Chauve, Cedric

    Comparing Genomes with Duplications: A Computational Complexity Point of View Guillaume Blin are interested in the computational complexity of computing (dis)similarity measures between two genomes when they contain duplicated genes or genomic markers, a problem that happens frequently when comparing whole

  15. NEWS & VIEWS synchrotron or helium-lamp studies. But

    E-Print Network [OSTI]

    Loss, Daniel

    NEWS & VIEWS synchrotron or helium-lamp studies. But the low energy of the laser photons raises, which should be stronger the lower the kinetic energy of the outgoing electron? Further studies is equivalent to a `pole singularity' in the Green's function. Phil Anderson argues that in the strange metal

  16. Abstract View PERCEPTION OF CONSEQUENCES OF ACTIONS: AN FMRI STUDY

    E-Print Network [OSTI]

    Itti, Laurent

    of a consistent perspective. Previous fMRI studies designed to investigate the perception of mechanical causality was found. Results were interpreted as supporting the view that the perception of elementary mechanical causality events is automatically processed by early low-level mechanisms not influenced by top

  17. View Dependent Isosurface Extraction Yarden Livnat Charles Hansen

    E-Print Network [OSTI]

    Livnat, Yarden

    triangles and is accomplished by the graphics hardware. While the latest isosurface extraction methods have isosurface extraction (NOISE) method. Both NOISE and the later optimal isosurface extraction methodView Dependent Isosurface Extraction Yarden Livnat Charles Hansen University of Utah Abstract We

  18. 1 1999 Rational Software Corporation The View from the Front

    E-Print Network [OSTI]

    Demurjian, Steven A.

    1 ©1999 Rational Software Corporation 3/7/99 R UML The View from the Front James Rumbaugh 9 March 1999 Rational Software Corporation #12; 2 ©1999 Rational Software Corporation 3/7/99 R Evolution Start 1/95 UML 1.3 RTF report 4/99 OMG feedback #12; 3 ©1999 Rational Software Corporation 3/7/99 R UML

  19. NEWS & VIEWS nEutRon StaRS

    E-Print Network [OSTI]

    Loss, Daniel

    NEWS & VIEWS nEutRon StaRS a magnetar by another name Fernando Camilo is at the Columbia core, held stable by neutron degeneracy pressure -- with more mass than the Sun within a 10 km radius -- has central densities comparable to those of nuclei. What does the neutron star sky look like, made

  20. Climate Change -A Personal View Few people in the western

    E-Print Network [OSTI]

    P A G E 4 Climate Change - A Personal View Few people in the western world, or indeed further- cal evidence for climate change over past millennia? If you think it is, then you are naturally drawn afield, can now be unaware of the concern expressed in the media about the possi- ble effects of climate

  1. news and views A key issue for hydrogen storage materi-

    E-Print Network [OSTI]

    Palumbi, Stephen

    news and views A key issue for hydrogen storage materi- als is that the hydrogenation and dehydro be possible to discover stable hydrogen hydrates with higher storage Hydrogen Posture Plan www.eere.energy.gov/hydrogenandfuelcells/pdfs/ hydrogen_posture_plan.pdf 7. Kuhs, W

  2. News and Views International hydrogen association for hydrogen energy

    E-Print Network [OSTI]

    Mench, Matthew M.

    News and Views International hydrogen association for hydrogen energy design competition applied State University IAHE Chapter Student Members, USA c Electrochemical Energy Storage and Conversion Association for Hydrogen Energy supplied a team of 12 members to enter the 1st IAHE Hydrogen Design

  3. Lithium Hexamethyldisilazide: A View of Lithium Ion Solvation

    E-Print Network [OSTI]

    Collum, David B.

    Lithium Hexamethyldisilazide: A View of Lithium Ion Solvation through a Glass-Bottom Boat BRETT L and reactivities, we were drawn to lithium hexamethyldisilazide (LiHMDS; (Me3Si)2NLi) by its promi- nence principles of lithium ion coordination chemistry.2 Understanding how solvation influences organolithium

  4. View this email in a web page Annual Open House

    E-Print Network [OSTI]

    View this email in a web page Annual Open House The 2015 Annual CVHS Open House was a great success Kaitlyn Belanger, class of 2018. Drs. Quinn own and operate Town East Galloway Animal Hospital in Mesquite addition to the award, which is sponsored by Merck Animal Health and the AVC, Merck will make a $2

  5. Delayed Afterglow Onset Interpreted as Baryon-Poor Viewing Angle

    E-Print Network [OSTI]

    David Eichler

    2005-03-24

    We have suggested previously that baryons in GRB fireballs infiltrate from the surrounding walls that collimate the fireball. The efficiency $\\epsilon_b$ for generating blast energy can then be angle dependent. Delayed onset of afterglow can be interpreted as being due to a baryon-poor viewing angle.

  6. research news Renewing an old view of chloroplasts

    E-Print Network [OSTI]

    Tobin, Elaine

    that chloroplasts can form tubular connec- tions, and that these are capable of allow- ing proteins to be exchanged support to a different and older view of a dynamic chloroplast, able to exchange macromolecules with other chloroplasts and perhaps other organelles. Tubular connections The work of KShler et al.1 demonstrates

  7. An Inductive Database Prototype Based on Virtual Mining Views

    E-Print Network [OSTI]

    Robardet, Céline

    An Inductive Database Prototype Based on Virtual Mining Views Hendrik Blockeel K.U. Leuven Leuven, Belgium Toon Calders T.U. Eindhoven Eindhoven, The Netherlands Elisa Fromont K.U. Leuven Leuven, Belgium Bart Goethals Universiteit Antwerpen Antwerp, Belgium Adriana Prado Universiteit Antwerpen Antwerp

  8. Grading Instructions in PeopleSoft View Student Grades

    E-Print Network [OSTI]

    Fletcher, Robin

    - QUNIV Enter your Term - Select from the list of valid values that appear after you clicked on the Search => Student Grades Navigation: Records & Enrollment => Student Term Information => Student Grades Enter;View Student Grades - Demo 3/21/2011 13 Navigation: Records & Enrollment => Student Term Information

  9. In all cases, ALOX5AP and its synonyms were highlighted automati-cally in each view. To highlight disease terms in these views, we

    E-Print Network [OSTI]

    Cai, Long

    the results easy to explore. The novo|seek search box interface allows the user to enter a term (or the production of substances that cause inflammation, such as leukotrienes1. When we entered ALOX5AP as a search a simple view (title, journal and author), a snippet view (a simple view and the search term with flanking

  10. Periodontium destruction associated with oncology therapy. Five case reports

    SciTech Connect (OSTI)

    Wright, W.E.

    1987-08-01

    Radiation treatment to the head and neck and cytotoxic chemotherapy can produce deleterious side effects to the periodontium that are generally transient in nature, reversible, and do not result in permanently visible defects. However, combinations of the malignant disease itself, the direct and indirect effects of medical therapy and associated oral infections, along with local trauma can lead to periodontal tissue destruction with resulting permanent architectural defects. Five case reports illustrate destructive alterations of the periodontium that were associated with oncology therapy. Proposed guidelines for periodontal treatment of compromised individuals undergoing oncology therapies are suggested.

  11. Cold atmospheric plasma in cancer therapy

    SciTech Connect (OSTI)

    Keidar, Michael; Shashurin, Alex; Volotskova, Olga; Ann Stepp, Mary; Srinivasan, Priya; Sandler, Anthony; Trink, Barry

    2013-05-15

    Recent progress in atmospheric plasmas has led to the creation of cold plasmas with ion temperature close to room temperature. This paper outlines recent progress in understanding of cold plasma physics as well as application of cold atmospheric plasma (CAP) in cancer therapy. Varieties of novel plasma diagnostic techniques were developed recently in a quest to understand physics of CAP. It was established that the streamer head charge is about 10{sup 8} electrons, the electrical field in the head vicinity is about 10{sup 7} V/m, and the electron density of the streamer column is about 10{sup 19} m{sup ?3}. Both in-vitro and in-vivo studies of CAP action on cancer were performed. It was shown that the cold plasma application selectively eradicates cancer cells in-vitro without damaging normal cells and significantly reduces tumor size in-vivo. Studies indicate that the mechanism of action of cold plasma on cancer cells is related to generation of reactive oxygen species with possible induction of the apoptosis pathway. It is also shown that the cancer cells are more susceptible to the effects of CAP because a greater percentage of cells are in the S phase of the cell cycle.

  12. Stimulation of dendritic cells enhances immune response after photodynamic therapy

    E-Print Network [OSTI]

    Mroz, Pawel

    Photodynamic therapy (PDT) involves the administration of photosensitizers followed by illumination of the primary tumor with red light producing reactive oxygen species that cause vascular shutdown and tumor cell necrosis ...

  13. A novel nanodelivery system for combination tumor therapy

    E-Print Network [OSTI]

    Eavarone, David A. (David Alan)

    2004-01-01

    Anti-angiogenic therapy offers many benefits over traditional cytotoxic chemotherapy including fewer toxic side effects and the reduced development of drug resistance. Anti-angiogenics alone have not proven effective in ...

  14. Radiation Therapy for Neovascular Age-related Macular Degeneration

    SciTech Connect (OSTI)

    Kishan, Amar U.; Modjtahedi, Bobeck S.; Morse, Lawrence S.; Lee, Percy

    2013-03-01

    In the enormity of the public health burden imposed by age-related macular degeneration (ARMD), much effort has been directed toward identifying effective and efficient treatments. Currently, anti-vascular endothelial growth factor (VEGF) injections have demonstrated considerably efficacy in treating neovascular ARMD, but patients require frequent treatment to fully benefit. Here, we review the rationale and evidence for radiation therapy of ARMD. The results of early photon external beam radiation therapy are included to provide a framework for the sequential discussion of evidence for the usage of stereotactic radiation therapy, proton therapy, and brachytherapy. The evidence suggests that these 3 modern modalities can provide a dose-dependent benefit in the treatment of ARMD. Most importantly, preliminary data suggest that all 3 can be used in conjunction with anti-VEGF therapeutics, thereby reducing the frequency of anti-VEGF injections required to maintain visual acuity.

  15. Predicting Couple Therapy Dropouts in Veteran Administration Medical Centers 

    E-Print Network [OSTI]

    Hsueh, Annie

    2012-10-19

    The present study examined predictors of couple therapy dropout in the VA medical centers using six different dropout criteria. The most accurate dropout definitions included using a statistical modeling procedure to determine whether the client...

  16. Köebner phenomenon induced by cupping therapy in a psoriasis patient

    E-Print Network [OSTI]

    Yu, Rui-xing; Hui, Yun; Li, Cheng-rang

    2013-01-01

    The pathogenesis of KP in psoriasis and other diseases isto cupping therapy in a psoriasis patient. To our knowledge,R K. The biology of psoriasis. An experimental study of the

  17. Grounded-Encounter Therapy: A Sociodiagnostic and Sociotherapeutic Approach

    E-Print Network [OSTI]

    Swan, L. Alex

    1985-01-01

    patterns of their relationships. The milieu of the so­ cial context is the particular setting that has been created by the coming together of human systems and the -94- Grounded-Encounter Therapy experiences or ways in which the human systems have tried... therein. It grounds the therapy in social diagnosis and explanations of the social situation through encounter between and among the individuals, and between the individuals and the social milieu of the human systems. A process and content is established...

  18. Review of ion beam therapy: Present and Future

    SciTech Connect (OSTI)

    Alonso, Jose R.

    2000-06-01

    First therapy efforts at the Bevalac using neon ions took place in the 70's and 80's. Promising results led to construction of HIMAC in Chiba Japan, and more recently to therapy trials at GSI. Both these facilities are now treating patients with carbon beams. Advances in both accelerator technology and beam delivery have taken place at these two centers. Plans are well along for new facilities in Europe and Japan.

  19. Target tracking using DMLC for volumetric modulated arc therapy: A simulation study

    SciTech Connect (OSTI)

    Sun Baozhou; Rangaraj, Dharanipathy; Papiez, Lech; Oddiraju, Swetha; Yang Deshan; Li, H. Harold

    2010-12-15

    Purpose: Target tracking using dynamic multileaf collimator (DMLC) is a promising approach for intrafraction motion management in radiation therapy. The purpose of this work is to develop a DMLC tracking algorithm capable of delivering volumetric-modulated arc therapy (VMAT) to the targets that experience two-dimensional (2D) rigid motion in the beam's eye view. Methods: The problem of VMAT delivery to moving targets is formulated as a control problem with constraints. The relationships between gantry speed, gantry acceleration, MLC leaf-velocity, dose rate, and target motion are derived. An iterative search algorithm is developed to find numerical solutions for efficient delivery of a specific VMAT plan to the moving target using 2D DMLC tracking. The delivery of five VMAT lung plans is simulated. The planned and delivered fluence maps in the target-reference frame are calculated and compared. Results: The simulation demonstrates that the 2D tracking algorithm is capable of delivering the VMAT plan to a moving target fast and accurately without violating the machine constraints and the integrity of the treatment plan. The average delivery time is only 29 s longer than that of no-tracking delivery, 101 versus 72 s, respectively. The fluence maps are normalized to 200 MU and the average root-mean-square error between the desired and the delivered fluence is 2.1 MU, compared to 14.8 MU for no-tracking and 3.6 MU for one-dimensional tracking. Conclusions: A locally optimal MLC tracking algorithm for VMAT delivery is proposed, aiming at shortest delivery time while maintaining treatment plan invariant. The inconsequential increase of treatment time due to DMLC tracking is clinically desirable, which makes VMAT with DMLC tracking attractive in treating moving tumors.

  20. West View, Pennsylvania: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page| Open Energy Information Serbia-EnhancingEtGeorgia: Energy ResourcesTurin, New York: Energy ResourcesView,

  1. Satellite-viewed cloud signatures associated with extratropical cyclogenesis 

    E-Print Network [OSTI]

    Lapierre, Robert Lucien

    1973-01-01

    SATELLITE-VIEWED CLOUD SIGNATURES ASSOCIATED WITH EXTRATROPICAL CYCLOGENESIS A Thesis by ROBERT LUCIEN LAPIERRE Submitted to the Graduate College of Texas ASM University in partial fulfillment of the requirement for the degree of MASTER... OF SCIENCE May 1973 Major Subject: Meteorology SATELLITE-VIENED CLOUD SIGNATURES ASSOCIATED WITH EXTRATROPICAL CYCLOGENESIS A Thesis by ROBERT LUCIEN LAPIERRE Appi"o ed as to st~le and content by: n llcgrceo~& (C ai rman of Conmi t te~ YemberI Hay...

  2. The Oblique Basis Method from an Engineering Point of View

    E-Print Network [OSTI]

    V. G. Gueorguiev

    2012-10-16

    The oblique basis method is reviewed from engineering point of view related to vibration and control theory. Examples are used to demonstrate and relate the oblique basis in nuclear physics to the equivalent mathematical problems in vibration theory. The mathematical techniques, such as principal coordinates and root locus, used by vibration and control theory engineers are shown to be relevant to the Richardson - Gaudin pairing-like problems in nuclear physics.

  3. Harbor View, Ohio: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QAsource History View New PagesSustainableGlynnMassachusetts: EnergySoftware Inc Jump to:

  4. Grand View Estates, Colorado: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QAsource History View New PagesSustainableGlynn County, Georgia: EnergyGorlitzLedge, Michigan:River, Ohio:

  5. Southern View, Illinois: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page| Open Energy Information Serbia-Enhancing CapacityVectren) Jump to: navigation, search Name: SouthernRockiesSolarView,

  6. Lake View, Alabama: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QAsource History View NewTexas:Montezuma, Arizona: Energy Resources Jump to: navigation,Utah: Energy

  7. A Comparison of Three Music Therapy Introduction Dialogues on Acceptance of Music Therapy Services by Cancer Patients

    E-Print Network [OSTI]

    Barck, Leanne Kathleen

    2014-12-31

    ABSTRACT The purpose of this study was to compare the effectiveness of 3 different music therapy introduction dialogues with cancer patients. Relationships between patient-reported anxiety levels, sex, and age and the acceptance rate of music...

  8. A hardware investigation of robotic SPECT for functional and molecular imaging onboard radiation therapy systems

    SciTech Connect (OSTI)

    Yan, Susu, E-mail: susu.yan@duke.edu; Tough, MengHeng [Medical Physics Graduate Program, Duke University, Durham, North Carolina 27710 (United States); Bowsher, James; Yin, Fang-Fang [Medical Physics Graduate Program, Duke University, Durham, North Carolina 27710 and Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina 27710 (United States); Cheng, Lin [Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina 27710 (United States)

    2014-11-01

    Purpose: To construct a robotic SPECT system and to demonstrate its capability to image a thorax phantom on a radiation therapy flat-top couch, as a step toward onboard functional and molecular imaging in radiation therapy. Methods: A robotic SPECT imaging system was constructed utilizing a gamma camera detector (Digirad 2020tc) and a robot (KUKA KR150 L110 robot). An imaging study was performed with a phantom (PET CT Phantom{sup TM}), which includes five spheres of 10, 13, 17, 22, and 28 mm diameters. The phantom was placed on a flat-top couch. SPECT projections were acquired either with a parallel-hole collimator or a single-pinhole collimator, both without background in the phantom and with background at 1/10th the sphere activity concentration. The imaging trajectories of parallel-hole and pinhole collimated detectors spanned 180° and 228°, respectively. The pinhole detector viewed an off-centered spherical common volume which encompassed the 28 and 22 mm spheres. The common volume for parallel-hole system was centered at the phantom which encompassed all five spheres in the phantom. The maneuverability of the robotic system was tested by navigating the detector to trace the phantom and flat-top table while avoiding collision and maintaining the closest possible proximity to the common volume. The robot base and tool coordinates were used for image reconstruction. Results: The robotic SPECT system was able to maneuver parallel-hole and pinhole collimated SPECT detectors in close proximity to the phantom, minimizing impact of the flat-top couch on detector radius of rotation. Without background, all five spheres were visible in the reconstructed parallel-hole image, while four spheres, all except the smallest one, were visible in the reconstructed pinhole image. With background, three spheres of 17, 22, and 28 mm diameters were readily observed with the parallel-hole imaging, and the targeted spheres (22 and 28 mm diameters) were readily observed in the pinhole region-of-interest imaging. Conclusions: Onboard SPECT could be achieved by a robot maneuvering a SPECT detector about patients in position for radiation therapy on a flat-top couch. The robot inherent coordinate frames could be an effective means to estimate detector pose for use in SPECT image reconstruction.

  9. Evolving Materialized Views in Data Warehouse Chuan Zhang,* Xin Yao: Jian Yang t

    E-Print Network [OSTI]

    Yao, Xin

    Evolving Materialized Views in Data Warehouse Chuan Zhang,* Xin Yao: Jian Yang t Abstract- A data have some views materialized, and some vir- 'Chuan Zhang and Xin Yao are with the School of Computer

  10. NATURE CLIMATE CHANGE | VOL 1 | JULY 2011 | www.nature.com/natureclimatechange 195 news & views

    E-Print Network [OSTI]

    Hoffman, Andrew J.

    ', with acceptance of the scienti c evidence for global warming tightly tied with liberal views6 . In short, it has inconvenient truth', liberal members of the public are more likely to endorse that view than conservatives

  11. Fast Multi-View Soft Shadowing via Fragment Reprojection Adam Marrs, Benjamin Watson, Christopher Healey

    E-Print Network [OSTI]

    Young, R. Michael

    Fast Multi-View Soft Shadowing via Fragment Reprojection Adam Marrs, Benjamin Watson, Christopher is constantly #12;2 Adam Marrs, Benjamin Watson, & Christopher Healey / Fast Multi-View Soft Shadowing via

  12. Multi-task and Multi-view Learning for Predicting Adverse Drug Reactions

    E-Print Network [OSTI]

    Zhang, Jintao

    2012-12-31

    , we use computational methods such as biological network analysis, multi-task learning, multi-view learning, and inductive multi-view multi-task learning to systematically investigate the modeling of various ADRs, and construct highly accurate models...

  13. California’s Energy Future: The View to 2050 - Summary Report

    E-Print Network [OSTI]

    Yang, Christopher

    2011-01-01

    Summit on America’s Energy Future (2008), http://www.natural gas. California’s Energy Future - The View to 2050supply California’ s Energy Future - The View to 2050 and

  14. Rain, Rain, Don't Go Away Taking a 360-Degree View of Water

    E-Print Network [OSTI]

    Christian, Eric

    Rain, Rain, Don't Go Away Taking a 360-Degree View of Water The Science of Photography National Flood Studies Field Campaign ­ 6 Taking a 360-Degree View of Water ­ 8 From GLOBE Star Student to GLOBE

  15. Pelvic Normal Tissue Contouring Guidelines for Radiation Therapy: A Radiation Therapy Oncology Group Consensus Panel Atlas

    SciTech Connect (OSTI)

    Gay, Hiram A., E-mail: hgay@radonc.wustl.edu [Washington University School of Medicine, St Louis, MO (United States); Barthold, H. Joseph [Commonwealth Hematology and Oncology, Weymouth, MA (United States); Beth Israel Deaconess Medical Center, Boston, MA (Israel); O'Meara, Elizabeth [Radiation Therapy Oncology Group, Philadelphia, PA (United States); Bosch, Walter R. [Washington University School of Medicine, St Louis, MO (United States); El Naqa, Issam [Department of Radiation Oncology, McGill University Health Center, Montreal, Quebec (Canada); Al-Lozi, Rawan [Washington University School of Medicine, St Louis, MO (United States); Rosenthal, Seth A. [Radiation Oncology Centers, Radiological Associates of Sacramento, Sacramento, CA (United States); Lawton, Colleen [Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI (United States); Lee, W. Robert [Department of Radiation Oncology, Duke University Medical Center, Durham, NC (United States); Sandler, Howard [Cedars-Sinai Medical Center, Los Angeles, CA (United States); Zietman, Anthony [Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA (United States); Myerson, Robert [Washington University School of Medicine, St Louis, MO (United States); Dawson, Laura A. [Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario (Canada); Willett, Christopher [Department of Radiation Oncology, Duke University Medical Center, Durham, NC (United States); Kachnic, Lisa A. [Department of Radiation Oncology, Boston Medical Center, Boston University School of Medicine, Boston, MA (United States); Jhingran, Anuja [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX (United States); Portelance, Lorraine [University of Miami, Miami, FL (United States); Ryu, Janice [Radiation Oncology Centers, Radiological Associates of Sacramento, Sacramento, CA (United States); and others

    2012-07-01

    Purpose: To define a male and female pelvic normal tissue contouring atlas for Radiation Therapy Oncology Group (RTOG) trials. Methods and Materials: One male pelvis computed tomography (CT) data set and one female pelvis CT data set were shared via the Image-Guided Therapy QA Center. A total of 16 radiation oncologists participated. The following organs at risk were contoured in both CT sets: anus, anorectum, rectum (gastrointestinal and genitourinary definitions), bowel NOS (not otherwise specified), small bowel, large bowel, and proximal femurs. The following were contoured in the male set only: bladder, prostate, seminal vesicles, and penile bulb. The following were contoured in the female set only: uterus, cervix, and ovaries. A computer program used the binomial distribution to generate 95% group consensus contours. These contours and definitions were then reviewed by the group and modified. Results: The panel achieved consensus definitions for pelvic normal tissue contouring in RTOG trials with these standardized names: Rectum, AnoRectum, SmallBowel, Colon, BowelBag, Bladder, UteroCervix, Adnexa{sub R}, Adnexa{sub L}, Prostate, SeminalVesc, PenileBulb, Femur{sub R}, and Femur{sub L}. Two additional normal structures whose purpose is to serve as targets in anal and rectal cancer were defined: AnoRectumSig and Mesorectum. Detailed target volume contouring guidelines and images are discussed. Conclusions: Consensus guidelines for pelvic normal tissue contouring were reached and are available as a CT image atlas on the RTOG Web site. This will allow uniformity in defining normal tissues for clinical trials delivering pelvic radiation and will facilitate future normal tissue complication research.

  16. 414 NATURE PHYSICS | VOL 10 | JUNE 2014 | www.nature.com/naturephysics news & views

    E-Print Network [OSTI]

    Loss, Daniel

    in the polarized flux of scattered light6 . This polarized light provided a periscope for viewing the inner regions

  17. Travel, work, and telecommunications: a view of the electronics revolution and its potential impacts

    E-Print Network [OSTI]

    Garrison, William L.; Deakin, Elizabeth

    2006-01-01

    TELECOMMUNICATIONS: A VIEW OF THE ELECTRONICS REVOLUTION ANDtechnologies and other electronics innovations ontelecommunications and other electronics innovations on the

  18. Biochemical Response to Androgen Deprivation Therapy Before External Beam Radiation Therapy Predicts Long-term Prostate Cancer Survival Outcomes

    SciTech Connect (OSTI)

    Zelefsky, Michael J.; Gomez, Daniel R.; Polkinghorn, William R.; Pei, Xin; Kollmeier, Marisa

    2013-07-01

    Purpose: To determine whether the response to neoadjuvant androgen deprivation therapy (ADT) defined by a decline in prostate-specific antigen (PSA) to nadir values is associated with improved survival outcomes after external beam radiation therapy (EBRT) for prostate cancer. Methods and Materials: One thousand forty-five patients with localized prostate cancer were treated with definitive EBRT in conjunction with neoadjuvant and concurrent ADT. A 6-month course of ADT was used (3 months during the neoadjuvant phase and 2 to 3 months concurrently with EBRT). The median EBRT prescription dose was 81 Gy using a conformal-based technique. The median follow-up time was 8.5 years. Results: The 10-year PSA relapse-free survival outcome among patients with pre-radiation therapy PSA nadirs of ?0.3 ng/mL was 74.3%, compared with 57.7% for patients with higher PSA nadir values (P<.001). The 10-year distant metastases-free survival outcome among patients with pre-radiation therapy PSA nadirs of ?0.3 ng/mL was 86.1%, compared with 78.6% for patients with higher PSA nadir values (P=.004). In a competing-risk analysis, prostate cancer-related deaths were also significantly reduced among patients with pre-radiation therapy PSA nadirs of <0.3 ng/mL compared with higher values (7.8% compared with 13.7%; P=.009). Multivariable analysis demonstrated that the pre-EBRT PSA nadir value was a significant predictor of long-term biochemical tumor control, distant metastases-free survival, and cause-specific survival outcomes. Conclusions: Pre-radiation therapy nadir PSA values of ?0.3 ng/mL after neoadjuvant ADT were associated with improved long-term biochemical tumor control, reduction in distant metastases, and prostate cancer-related death. Patients with higher nadir values may require alternative adjuvant therapies to improve outcomes.

  19. Valley View, Ohio: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page| Open Energy Information Serbia-EnhancingEt Al.,Turin, New York:PowerNewPumatyUvaldeVallesEnergyPark, Oklahoma:View,

  20. Ground control failures. A pictorial view of case studies

    SciTech Connect (OSTI)

    Peng, S.S.

    2007-07-01

    The book shows, in pictorial views, many forms and/or stages of types of failures in mines, for instance, cutter, roof falls, and cribs. In each case, the year of occurrence is stated in the beginning so that the environment or technological background under which it occurred are reflected. The narrative than begins with the mining and geological conditions, followed by a description of the ground control problems and recommended solutions and results, if any. The sections cover failure of pillars, roof falls, longwall, roof bolting, multiple-seam mining, floor heave, longwall, flooding and weathering of coal, old workings, and shortwall and thin-seam plow longwall.

  1. Consumer Views on Transportation and Energy (Third Edition)

    SciTech Connect (OSTI)

    Kubik, M.

    2006-01-01

    This report has been assembled to provide the U.S. Department of Energy's (DOE's) Office of Energy Efficiency and Renewable Energy (EERE) with an idea of how the American public views various transportation, energy, and environmental issues. The data presented in this report have been drawn from multiple sources: surveys conducted by the Opinion Research Corporation (ORC) for the National Renewable Energy Laboratory (NREL) that are commissioned and funded by EERE, Gallup polls, news organization polls, surveys conducted by independent groups and academic institutions, and other sources.

  2. BloombergBusiness: Viewed from space: less corn

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 OutreachProductswsicloudwsiclouddenDVA N C E D B L O OLaura|BilayerBiomimetic Dye MoleculesBlakeViewed from space:

  3. Forest View, Illinois: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QAsource History View New PagesSustainable Urban Transport JumpFlowood,Pevafersa JVOhio: EnergyInformation 5

  4. Skyline View, Pennsylvania: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page| Open Energy Information Serbia-Enhancing Capacity forSilicium de ProvenceSolar Jump to: navigation, search Name:View,

  5. Lake View, Maine: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QAsource History View NewTexas:Montezuma, Arizona: Energy Resources Jump to: navigation,Utah: EnergyMaine: Energy

  6. A View from the Bridge - DOE Perspective | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:Financing ToolInternationalReportOffice | DepartmentVery1, in:QuarterlyA SolarAA View from the

  7. Bay View, Ohio: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION JEnvironmental Jump to:EAandAmminexInformationArkansas: Energy ResourcesPoint,View, Ohio:

  8. City of Mountain View, Missouri (Utility Company) | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION JEnvironmentalBowerbank,CammackFLIRChurchFontanelle, IowaIowaCityWater) JumpLouisianaView, Missouri

  9. Logan View Public Schools Wind Project | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION J APPENDIXsource History ViewInformationWindsCompressedListguided waves fromLocustLoessLogan

  10. A View from the Bridge - DOE Perspective | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustmentsShirleyEnergyTher i n c i p a l De p u t y A s s iof1 of 8(MayPROCEEDINGS,Broad view of DOE's

  11. G-TEAMS at Mountain View High School Jennifer Hendryx, Mathias Reynolds

    E-Print Network [OSTI]

    Lega, Joceline

    G-TEAMS at Mountain View High School Jennifer Hendryx, Mathias Reynolds Who are we? Jennifer: Math teacher at Mountain View High school; teaches Alg. II, College Ready Math, and SpEd Alg. I. Goals in physics, Jennifer has been able to participate in Mountain View's Ac Dec as the science coach

  12. "New View" of Protein Folding Reconciled with the Old Through Multiple Unfolding Simulations

    E-Print Network [OSTI]

    Lazaridis, Themis

    "New View" of Protein Folding Reconciled with the Old Through Multiple Unfolding Simulations Themis folding with a preferred pathway on a funnel-like average energy surface. A "new view" of protein folding is the primary unfolding event. The results suggest a synthesis of the "new" and the classical view of protein

  13. Molecular structure in soil humic substances: The new view

    SciTech Connect (OSTI)

    Sutton, Rebecca; Sposito, Garrison

    2005-04-21

    A critical examination of published data obtained primarily from recent nuclear magnetic resonance spectroscopy, X-ray absorption near-edge structure spectroscopy, electrospray ionization-mass spectrometry, and pyrolysis studies reveals an evolving new view of the molecular structure of soil humic substances. According to the new view, humic substances are collections of diverse, relatively low molecular mass components forming dynamic associations stabilized by hydrophobic interactions and hydrogen bonds. These associations are capable of organizing into micellar structures in suitable aqueous environments. Humic components display contrasting molecular motional behavior and may be spatially segregated on a scale of nanometers. Within this new structural context, these components comprise any molecules intimately associated with a humic substance, such that they cannot be separated effectively by chemical or physical methods. Thus biomolecules strongly bound within humic fractions are by definition humic components, a conclusion that necessarily calls into question key biogeochemical pathways traditionally thought to be required for the formation of humic substances. Further research is needed to elucidate the intermolecular interactions that link humic components into supramolecular associations and to establish the pathways by which these associations emerge from the degradation of organic litter.

  14. RESEARCH ARTICLE Interstitial iron concentrations across multicrystalline

    E-Print Network [OSTI]

    wafers were alkaline etched and received a 30 min double PROGRESS IN PHOTOVOLTAICS: RESEARCH Photovoltaics Centre of Excellence, The University of New South Wales, Sydney, New South Wales 2052, Australia

  15. Overview of Light-Ion Beam Therapy

    SciTech Connect (OSTI)

    Chu, William T.

    2006-03-16

    In 1930, Ernest Orlando Lawrence at the University of California at Berkeley invented the cyclotron. One of his students, M. Stanley Livingston, constructed a 13-cm diameter model that had all the features of early cyclotrons, accelerating protons to 80 keV using less than 1 kV on a semi-circular accelerating electrode, now called the ''dee''. Soon after, Lawrence constructed the first two-dee 27-Inch (69-cm) Cyclotron, which produced protons and deuterons of 4.8 MeV. In 1939, Lawrence constructed the 60-Inch (150-cm) Cyclotron, which accelerated deuterons to 19 MeV. Just before WWII, Lawrence designed a 184-inch cyclotron, but the war prevented the building of this machine. Immediately after the war ended, the Veksler-McMillan principle of phase stability was put forward, which enabled the transformation of conventional cyclotrons to successful synchrocyclotrons. When completed, the 184-Inch Synchrocyclotron produced 340-MeV protons. Following it, more modern synchrocyclotrons were built around the globe, and the synchrocyclotrons in Berkeley and Uppsala, together with the Harvard cyclotron, would perform pioneering work in treatment of human cancer using accelerated hadrons (protons and light ions). When the 184-Inch Synchrocyclotron was built, Lawrence asked Robert Wilson, one of his former graduate students, to look into the shielding requirements for of the new accelerator. Wilson soon realized that the 184-Inch would produce a copious number of protons and other light ions that had enough energy to penetrate human body, and could be used for treatment of deep-seated diseases. Realizing the advantages of delivering a larger dose in the Bragg peak when placed inside deep-seated tumors, he published in a medical journal a seminal paper on the rationale to use accelerated protons and light ions for treatment of human cancer. The precise dose localization provided by protons and light ions means lower doses to normal tissues adjacent to the treatment volume compared to those in conventional (photon) treatments. Wilson wrote his personal account of this pioneering work in 1997. In 1954 Cornelius Tobias and John Lawrence at the Radiation Laboratory (former E.O. Lawrence Berkeley National Laboratory) of the University of California, Berkeley performed the first therapeutic exposure of human patients to hadron (deuteron and helium ion) beams at the 184-Inch Synchrocyclotron. By 1984, or 30 years after the first proton treatment at Berkeley, programs of proton radiation treatments had opened at: University of Uppsala, Sweden, 1957; the Massachusetts General Hospital-Harvard Cyclotron Laboratory (MGH/HCL), USA, 1961; Dubna (1967), Moscow (1969) and St Petersburg (1975) in Russia; Chiba (1979) and Tsukuba (1983) in Japan; and Villigen, Switzerland, 1984. These centers used the accelerators originally constructed for nuclear physics research. The experience at these centers has confirmed the efficacy of protons and light ions in increasing the tumor dose relative to normal tissue dose, with significant improvements in local control and patient survival for several tumor sites. M.R. Raju reviewed the early clinical studies. In 1990, the Loma Linda University Medical Center in California heralded in the age of dedicated medical accelerators when it commissioned its proton therapy facility with a 250-MeV synchrotron. Since then there has been a relatively rapid increase in the number of hospital-based proton treatment centers around the world, and by 2006 there are more than a dozen commercially-built facilities in use, five new facilities under construction, and more in planning stages. In the 1950s larger synchrotrons were built in the GeV region at Brookhaven (3-GeV Cosmotron) and at Berkeley (6-GeV Bevatron), and today most of the world's largest accelerators are synchrotrons. With advances in accelerator design in the early 1970s, synchrotrons at Berkeley and Princeton accelerated ions with atomic numbers between 6 and 18, at energies that permitted the initiation of several biological studies. It is worth noting that when th

  16. Instrumentation requirements from the user's view. [For airbreathing hypersonic engines

    SciTech Connect (OSTI)

    Harsha, P.T.

    1988-01-01

    The use of combustor diagnostics is considered from the point of view of demonstration of performance of an airbreathing hypersonic engine. The basic need is seen to be that of providing the data necessary to verify performance predictions for the engine as installed in the airplane. This necessitates the use of a diagnostics capability that can provide the inputs required by the computational analyses that will be used to assess this performance. Because of the cost of ground test facilities, a premium is placed on measurement technique reliability and redundancy of instrumentation. A mix of nonintrusive optical techniques and probe-based measurements is seen to be the best approach using current diagnostics capability; one such instrument mix is outlined for a ramjet/scramjet test program. 11 references.

  17. Scioto: A Framework for Global-ViewTask Parallelism

    SciTech Connect (OSTI)

    Dinan, James S.; Krishnamoorthy, Sriram; Larkins, D. B.; Nieplocha, Jaroslaw; Sadayappan, Ponnuswamy

    2008-09-09

    We introduce Scioto, Shared Collections of Task Objects, a framework for supporting task-parallelism in one-sided and global-view parallel programming models. Scioto provides lightweight, locality aware dynamic load balancing and interoperates with existing parallel models including MPI, SHMEM, CAF, and Global Arrays. Through task parallelism, the Scioto framework provides a solution for overcoming load imbalance and heterogeneity as well as dynamic mapping of computation onto emerging multicore architectures. In this paper, we present the design and implementation of the Scioto framework and demonstrate its effectiveness on the Unbalanced Tree Search (UTS) benchmark and two quantum chemistry codes: the closed shell Self-Consistent Field (SCF) method and a sparse tensor contraction kernel extracted from a coupled cluster computation. We explore the efficiency and scalability of Scioto through these sample applications and demonstrate that is offers low overhead, achieves good performance on heterogeneous and multicore clusters, and scales to hundreds of processors.

  18. Update: Oil protectionism - three views of US vulnerability

    SciTech Connect (OSTI)

    Not Available

    1987-06-30

    World oil prices seem to have stabilized above the US $18 mark, many US publics fear that market power will once again be transferred to the Organization of Petroleum Exporting Countries (OPEC). When the price was weak, many observers said the weakness reflected victory over OPEC, as if the 1986 oil price crash were a result of the Organization's failure to exert its selfish will. Now that prices are higher, will US dependency on OPEC mushroom, fueling a campaign to protect indigenous crude oil prices through effective import fees. In this issue, latest available official import statistics for three views on how US oil import dependency might be evolving are supplied. This issue also contains: (1) ED refining netback data for the US Gulf and West Coasts, Rotterdam, and Singapore for late June 1987; and (2) the ED fuel price/tax series for countries of the Eastern Hemisphere, June 1987 edition. 4 figures, 5 tables.

  19. Noise as Therapy: A Prelude to Computationally-Based Neurology?

    E-Print Network [OSTI]

    Milton, John G.

    Noise as Therapy: A Prelude to Computationally-Based Neurology? Disturbances of the autonomic of pharmacological agents. The benefits were obtained by stimulating the vestibular nuclei with noise, i.e. electri de- signed to have the 1/f-type power spectrum character- istic of noise measured in the nervous

  20. Proceedings of the first international symposium on neutron capture therapy

    SciTech Connect (OSTI)

    Fairchild, R.G.; Brownell, G.L. (eds.)

    1982-01-01

    This meeting was arranged jointly by MIT and BNL in order to illuminate progress in the synthesis and targeting of boron compounds and to evaluate and document progress in radiobiological and dosimetric aspects of neutron capture therapy. It is hoped that this meeting will facilitate transfer of information between groups working in these fields, and encourage synergistic collaboration.

  1. The Particle Therapy Cancer Research Institute is a member of

    E-Print Network [OSTI]

    Nova? To deliver a lower-cost, smaller, lighter, more energy efficient solution for Proton Therapy without for commercial distribution at this time #12;Who is ProNova? ProNova has a strong History of Innovation Developed accessible to the cancer community #12;ProNova Design Principles - Workflow Precision, Productivity, Cost RT

  2. Construction of SAGA HIMAT for carbon ion cancer therapy

    SciTech Connect (OSTI)

    Kudo, Sho; Shioyama, Yoshiyuki; Endo, Masahiro; Kanazawa, Mitsutaka; Tsujii, Hirohiko; Totoki, Tadahide [Ion Beam Therapy Center , SAGA HIMAT Foundation, 1-802-3 Hondori-machi, Tosu, Saga 841-0033 (Japan)

    2013-04-19

    SAGA HIMAT is now under construction in Tosu city, Saga prefecture, Kyushu island, Japan. It will open in 2013 and become the fourth carbon ion beam cancer therapy center in Japan. It is a collaborative project among the local governments, industries and universities in northern Kyushu area.

  3. Miniature scintillating detector for small field radiation therapy D. Letourneaua)

    E-Print Network [OSTI]

    Pouliot, Jean

    are immersed in water into the radiation field. The detection device consists of two identical 10 m longMiniature scintillating detector for small field radiation therapy D. Le´tourneaua) Centre dosimeter consists of two identical radiation-resistant 10 m long silica optical fibers, each connected

  4. Transcriptional Targeting for Ovarian Cancer Gene Therapy E. Casado,*,

    E-Print Network [OSTI]

    Hemminki, Akseli

    REVIEW Transcriptional Targeting for Ovarian Cancer Gene Therapy E. Casado,*, D. M. Nettelbeck Paz, Madrid, Spain Received November 10, 2000 Ovarian carcinoma is a leading cause of cancer death patients diagnosed with ovarian cancer are still low. Therefore, novel molecular therapeutic strat- egies

  5. A Systems Approach to Breast Cancer Carcinogenesis to Therapy

    E-Print Network [OSTI]

    A Systems Approach to Breast Cancer ­ Carcinogenesis to Therapy Speaker: Dr. Joe Gray Director, Center for Spatial Systems Biomedicine Oregon Health & Science University Date: Monday, April 18, 2011 that influence cancer behavior, (b) systems biology approaches to elucidate mechanisms by which cancer

  6. Impact of Cognitive Behavioral Therapy for Social Anxiety Disorder on the Neural Dynamics

    E-Print Network [OSTI]

    Gross, James J.

    Impact of Cognitive Behavioral Therapy for Social Anxiety Disorder on the Neural Dynamics Cognitive behavioral therapy (CBT) for social anxiety disorder (SAD) is thought to enhance cognitive-beliefs embedded in autobiographical social anxiety situations. RESULTS During reactivity trials, compared

  7. Thiourea derivatives, methods of their preparation and their use in neutron capture therapy of malignant melanoma

    DOE Patents [OSTI]

    Gabel, D.

    1991-06-04

    The present invention pertains to boron containing thiouracil derivatives, their method of preparations, and their use in the therapy of malignant melanoma using boron neutron capture therapy. No Drawings

  8. Boron containing compounds and their preparation and use in neutron capture therapy

    DOE Patents [OSTI]

    Gabel, D.

    1992-09-01

    The present invention pertains to boron containing thiouracil derivatives, their method of preparations, and their use in the therapy of malignant melanoma using boron neutron capture therapy. No Drawings

  9. Quantitative analysis of non-viral gene therapy in primary liver culture systems

    E-Print Network [OSTI]

    Tedford, Nathan C

    2007-01-01

    Gene therapy has the potential to cure thousands of diseases caused by genetic abnormalities, provide novel combination therapies for cancers and viral infections, and offer a new and effective platform for next generation ...

  10. Predictors of Postoperative Complications After Trimodality Therapy for Esophageal Cancer

    SciTech Connect (OSTI)

    Wang, Jingya [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Wei, Caimiao [Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Tucker, Susan L. [Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Myles, Bevan; Palmer, Matthew [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Hofstetter, Wayne L.; Swisher, Stephen G. [Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Ajani, Jaffer A. [Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Cox, James D.; Komaki, Ritsuko; Liao, Zhongxing [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Lin, Steven H., E-mail: SHLin@mdanderson.org [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States)

    2013-08-01

    Purpose: While trimodality therapy for esophageal cancer has improved patient outcomes, surgical complication rates remain high. The goal of this study was to identify modifiable factors associated with postoperative complications after neoadjuvant chemoradiation. Methods and Materials: From 1998 to 2011, 444 patients were treated at our institution with surgical resection after chemoradiation. Postoperative (pulmonary, gastrointestinal [GI], cardiac, wound healing) complications were recorded up to 30 days postoperatively. Kruskal-Wallis tests and ?{sup 2} or Fisher exact tests were used to assess associations between continuous and categorical variables. Multivariate logistic regression tested the association between perioperative complications and patient or treatment factors that were significant on univariate analysis. Results: The most frequent postoperative complications after trimodality therapy were pulmonary (25%) and GI (23%). Lung capacity and the type of radiation modality used were independent predictors of pulmonary and GI complications. After adjusting for confounding factors, pulmonary and GI complications were increased in patients treated with 3-dimensional conformal radiation therapy (3D-CRT) versus intensity modulated radiation therapy (IMRT; odds ratio [OR], 2.018; 95% confidence interval [CI], 1.104-3.688; OR, 1.704; 95% CI, 1.03-2.82, respectively) and for patients treated with 3D-CRT versus proton beam therapy (PBT; OR, 3.154; 95% CI, 1.365-7.289; OR, 1.55; 95% CI, 0.78-3.08, respectively). Mean lung radiation dose (MLD) was strongly associated with pulmonary complications, and the differences in toxicities seen for the radiation modalities could be fully accounted for by the MLD delivered by each of the modalities. Conclusions: The radiation modality used can be a strong mitigating factor of postoperative complications after neoadjuvant chemoradiation.

  11. Human neural stem cell therapy in a primate model for Parkinson's disease

    E-Print Network [OSTI]

    Wakeman, Dustin Robert

    2010-01-01

    therapies by either directly integrating and replacing host neural circuitry, or, secondarily, by rescuing and restoring the endogenous host milieu

  12. Updated 06/13 Doctor of Physical Therapy Stratford (DPT-South)

    E-Print Network [OSTI]

    Garfunkel, Eric

    of Physical Therapy degree program is offered by Rutgers, School of Health-Related Professions (SHRP in physical therapy. The Physical Therapy degree program is located on the Stratford campus of New Jersey, The State University, School of Health Related Professions. Our program's unique character is enriched

  13. Adaptive Robot Design with Hand and Face Tracking for Use in Autism Therapy

    E-Print Network [OSTI]

    O'Kane, Jason

    Adaptive Robot Design with Hand and Face Tracking for Use in Autism Therapy Laura Boccanfuso1 interactive games using hand and face tracking with a robot as a tool for autism therapy. The robot robotics 1 Introduction Robot-assisted autism therapy employs robots as social mediators for promot- ing

  14. HADRON CANCER THERAPY COMPLEX EMPLOYING NON-SCALING FFAG ACCELERATOR AND FIXED FIELD GANTRY DESIGN

    E-Print Network [OSTI]

    Keil, Eberhard

    HADRON CANCER THERAPY COMPLEX EMPLOYING NON-SCALING FFAG ACCELERATOR AND FIXED FIELD GANTRY DESIGN, Upton NY, USA Abstract Non-scaling FFAG rings for cancer hadron therapy offer reduced physical aperture of energies. INTRODUCTION Cancer proton therapy exists today in many medical facilities and many more

  15. Cancer photothermal therapy in the near-infrared region by using single-walled carbon nanotubes

    E-Print Network [OSTI]

    Resasco, Daniel

    Cancer photothermal therapy in the near-infrared region by using single-walled carbon nanotubes of SWNTs provide an opportunity for selective photothermal therapy for cancer treatment. Specifically, Co photothermal therapy for cancer treatment. © 2009 Society of Photo-Optical Instrumentation Engineers. DOI: 10

  16. Dynamic Pricing with Limited Supply Moshe Babaioff, Microsoft Research Silicon Valley, Mountain View CA, USA

    E-Print Network [OSTI]

    Fiat, Amos

    Dynamic Pricing with Limited Supply Moshe Babaioff, Microsoft Research Silicon Valley, Mountain University, Ithaca NY, USA Aleksandrs Slivkins, Microsoft Research Silicon Valley, Mountain View CA, USA We

  17. Network Performance Improvements For Web Services : : An End-to-End View

    E-Print Network [OSTI]

    Radhakrishnan, Sivasankar

    2014-01-01

    Modern Web Services . . . . . . . . . . . . . . . . . . . .handshake overhead for all web services accessed by ChromeImprovements For Web Services – An End-to-End View A

  18. Report of Energy Efficiency Study and Metering/Utilities Profile for Electricity Deregulation at Prairie View A&M University (PVAMU) Prairie View, Texas 

    E-Print Network [OSTI]

    Zhu, Y.; Claridge, D. E.; Giebler, T.; Abushakra, B.; Turner, W. D.

    1999-01-01

    The physical plant director and staff at Prairie View A&M University (PVAMU) do a good job of maintaining PVAMU facilities and keeping expenses down. During our visit, however, we were able to identify several opportunities ...

  19. Energy spectrum of black holes : a new view

    E-Print Network [OSTI]

    Abhishek Majhi

    2015-12-22

    Energy of a black hole is usually quantized by invoking some area quantization scheme after expressing the energy in terms of the horizon area. However, in this approach one has to quantize the local and asymptotic energy of the black hole separately and the two results do not manifest any physical correspondence with each other. Here, as opposed to this practice, we find the unique energy spectrum of black holes by adopting a top-down approach. The physical links among the underlying quantum theory, statistical mechanics and thermodynamics of the black hole horizon play the central role in determining the energy spectrum. The energy spectrum that we obtain, explicitly reveals the correspondence between asymptotic and local observations through the presence of the surface gravity of the horizon as a parameter in the spectrum, rather than being expressed as a function of area and consequently getting quantized in the usual approach. Thus, our result presents a new view as far as black hole energy quantization is concerned. The calculations are performed using the quantum geometric description of black hole horizons as laid down by loop quantum gravity.

  20. $?$-Ray Pulsars: Emission Zones and Viewing Geometries, A Computer Animation

    E-Print Network [OSTI]

    I. -A. Yadigaroglu; Roger W. Romani

    1994-06-08

    The computer animation illustrates the geometries described in a paper by the same authors. The preprint is available as number 9401045. The opening scene shows dipole field lines emanating from the polar caps of a rotating neutron star. The dipole axis is inclined along the green rods. The field lines shown are defined from the condition that they be tangent to the light cylinder (the cylindrical radius at which the tangential velocity of rotation reaches the speed of light). The static dipole field lines are smoothly morphed into the correct retarted-potential vacuum solutions. A red surface spanning these field lines is painted. In the next scene the blue surfaces represent the outer gaps above the surface of last closed field lines. High energy emission (blue) is produced in these outer gaps, and is beamed tangentially along the field lines. The radio emission (green) originates close to the surface of the star and is beamed along the dipole axes. The inclination angle $\\alpha$ of the dipole and the viewing angle $\\zeta$ are chosen to match the Crab parameters; $\\alpha$ = 70, $\\zeta$ = 65. The corresponding light curve is computed and shown for these angles, and the red dot traces rotation phase. The next scene shows the situation for angles appropriate to PSR1706-44; $\\alpha$ = 45, $\\zeta$ = 65. The final scene is a possibility for Geminga; $\\alpha$ = 20, $\\zeta$ = 75. These angles are poorly constrained as there is no radio emission.

  1. Viewing spin structures with soft x-ray microscopy

    SciTech Connect (OSTI)

    Fischer, Peter

    2010-06-01

    The spin of the electron and its associated magnetic moment marks the basic unit for magnetic properties of matter. Magnetism, in particular ferromagnetism and antiferromagnetism is described by a collective order of these spins, where the interaction between individual spins reflects a competition between exchange, anisotropy and dipolar energy terms. As a result the energetically favored ground state of a ferromagnetic system is a rather complex spin configuration, the magnetic domain structure. Magnetism is one of the eldest scientific phenomena, yet it is one of the most powerful and versatile utilized physical effects in modern technologies, such as in magnetic storage and sensor devices. To achieve highest storage density, the relevant length scales, such as the bit size in disk drives is now approaching the nanoscale and as such further developments have to deal with nanoscience phenomena. Advanced characterization tools are required to fully understand the underlying physical principles. Magnetic microscopes using polarized soft X-rays offer a close-up view into magnetism with unique features, these include elemental sensitivity due to X-ray magnetic dichroism effects as contrast mechanism, high spatial resolution provided by state-of-the-art X-ray optics and fast time resolution limited by the inherent time structure of current X-ray sources, which will be overcome with the introduction of ultrafast and high brilliant X-ray sources.

  2. A Novel Linear Accelerator For Image Guided Radiation Therapy

    SciTech Connect (OSTI)

    Ding Xiaodong; Boucher, Salime [RadiaBeam Technologies, 1717 Stewart St., Santa Monica, CA 90404 (United States)

    2011-06-01

    RadiaBeam is developing a novel linear accelerator which produces both kilovoltage ({approx}100 keV) X-rays for imaging, and megavoltage (6 to 20 MeV) X-rays for therapy. We call this system the DEXITron: Dual Energy X-ray source for Imaging and Therapy. The Dexitron is enabled by an innovation in the electromagnetic design of the linac, which allows the output energy to be rapidly switched from high energy to low energy. In brief, the method involves switching the phase of the radiofrequency (RF) power by 180 degrees at some point in the linac such that, after that point, the linac decelerates the beam, rather than accelerating it. The Dexitron will have comparable cost to other linacs, and avoids the problems associated with current IGRT equipment.

  3. Study on neutron radiation field of carbon ions therapy

    E-Print Network [OSTI]

    Xu, Jun-Kui; Li, Wu-Yuan; Yan, Wei-Wei; Chen, Xi-Meng; Mao, Wang; Pang, Cheng-Guo

    2015-01-01

    Carbon ions offer significant advantages for deep-seated local tumors therapy due to their physical and biological properties. Secondary particles, especially neutrons caused by heavy ion reactions should be carefully considered in treatment process and radiation protection. For radiation protection purposes, the FLUKA Code was used in order to evaluate the radiation field at deep tumor therapy room of HIRFL in this paper. The neutron energy spectra, neutron dose and energy deposition of carbon ion and neutron in tissue-like media was studied for bombardment of solid water target by 430MeV/u C ions. It is found that the calculated neutron dose have a good agreement with the experimental date, and the secondary neutron dose may not exceed one in a thousand of the carbon ions dose at Bragg peak area in tissue-like media.

  4. Study on neutron radiation field of carbon ions therapy

    E-Print Network [OSTI]

    Jun-Kui Xu; You-Wu Su; Wu-Yuan Li; Wei-Wei Yan; Xi-Meng Chen; Wang Mao; Cheng-Guo Pang

    2015-03-18

    Carbon ions offer significant advantages for deep-seated local tumors therapy due to their physical and biological properties. Secondary particles, especially neutrons caused by heavy ion reactions should be carefully considered in treatment process and radiation protection. For radiation protection purposes, the FLUKA Code was used in order to evaluate the radiation field at deep tumor therapy room of HIRFL in this paper. The neutron energy spectra, neutron dose and energy deposition of carbon ion and neutron in tissue-like media was studied for bombardment of solid water target by 430MeV/u C ions. It is found that the calculated neutron dose have a good agreement with the experimental date, and the secondary neutron dose may not exceed one in a thousand of the carbon ions dose at Bragg peak area in tissue-like media.

  5. Nanoscience and Nanotechnology: From Energy Applications to Advanced Medical Therapies

    ScienceCinema (OSTI)

    Tijana Rajh

    2010-01-08

    Dr. Rajh will present a general talk on nanotechnology ? an overview of why nanotechnology is important and how it is useful in various fields. The specific focus will be on Solar energy conversion, environmental applications and advanced medical therapies. She has broad expertise in synthesis and characterization of nanomaterials that are used in nanotechnology including novel hybrid systems connecting semiconductors to biological molecules like DNA and antibodies. This technology could lead to new gene therapy procedures, cancer treatments and other medical applications. She will also discuss technologies made possible by organizing small semiconductor particles called quantum dots, materials that exhibit a rich variety of phenomena that are size and shape dependent. Development of these new materials that harnesses the unique properties of materials at the 1-100 nanometer scale resulted in the new field of nanotechnology that currently affects many applications in technological and medical fields.

  6. Chemoradiotherapeutic wrinkled mesoporous silica nanoparticles for use in cancer therapy

    SciTech Connect (OSTI)

    Munaweera, Imalka; Balkus, Kenneth J. Jr., E-mail: Balkus@utdallas.edu, E-mail: Anthony.DiPasqua@unthsc.edu [Department of Chemistry, University of Texas at Dallas, 800 West Campbell Rd., Richardson, Texas 75080 (United States); Koneru, Bhuvaneswari; Shi, Yi; Di Pasqua, Anthony J., E-mail: Balkus@utdallas.edu, E-mail: Anthony.DiPasqua@unthsc.edu [Department of Pharmaceutical Sciences, University of North Texas System College of Pharmacy, University of North Texas Health Science Center, 3500 Camp Bowie Blvd., Fort Worth, Texas 76107 (United States)

    2014-11-01

    Over the last decade, the development and application of nanotechnology in cancer detection, diagnosis, and therapy have been widely reported. Engineering of vehicles for the simultaneous delivery of chemo- and radiotherapeutics increases the effectiveness of the therapy and reduces the dosage of each individual drug required to produce an observable therapeutic response. We here developed a novel chemoradiotherapeutic 1,2-dioleoyl-sn-glycero-3-phosphocholine lipid coated/uncoated platinum drug loaded, holmium-containing, wrinkled mesoporous silica nanoparticle. The materials were characterized with TEM, FTIR, {sup 1}H NMR, energy dispersive x-ray, inductively coupled plasma-mass spectrometry, and zeta potential measurements. In vitro platinum drug release from both lipid coated and uncoated chemoradiotherapeutic wrinkled mesoporous silica are reported. Various kinetic models were used to analyze the release kinetics. The radioactivity of the chemoradiotherapeutic nanocarriers was measured after neutron-activation.

  7. Halogenated sulfidohydroboranes for nuclear medicine and boron neutron capture therapy

    DOE Patents [OSTI]

    Miura, Michiko (Hampton Bays, NY); Slatkin, Daniel N. (Southold, NY)

    1995-10-03

    A method for performing boron neutron capture therapy for the treatment of tumors is disclosed. The method includes administering to a patient an iodinated sulfidohydroborane, a boron-10-containing compound. The site of the tumor is localized by visualizing the increased concentration of the iodine labelled compound at the tumor. The targeted tumor is then irradiated with a beam of neutrons having an energy distribution effective for neutron capture. Destruction of the tumor occurs due to high LET particle irradiation of the tissue secondary to the incident neutrons being captured by the boron-10 nuclei. Iodinated sulfidohydroboranes are disclosed which are especially suitable for the method of the invention. In a preferred embodiment, a compound having the formula Na.sub.4 B.sub.12 I.sub.11 SSB.sub.12 I.sub.11, or another pharmaceutically acceptable salt of the compound, may be administered to a cancer patient for boron neutron capture therapy.

  8. Halogenated sulfidohydroboranes for nuclear medicine and boron neutron capture therapy

    DOE Patents [OSTI]

    Miura, M.; Slatkin, D.N.

    1995-10-03

    A method for performing boron neutron capture therapy for the treatment of tumors is disclosed. The method includes administering to a patient an iodinated sulfidohydroborane, a boron-10-containing compound. The site of the tumor is localized by visualizing the increased concentration of the iodine labelled compound at the tumor. The targeted tumor is then irradiated with a beam of neutrons having an energy distribution effective for neutron capture. Destruction of the tumor occurs due to high LET particle irradiation of the tissue secondary to the incident neutrons being captured by the boron-10 nuclei. Iodinated sulfidohydroboranes are disclosed which are especially suitable for the method of the invention. In a preferred embodiment, a compound having the formula Na{sub 4}B{sub 12}I{sub 11}SSB{sub 12}I{sub 11}, or another pharmaceutically acceptable salt of the compound, may be administered to a cancer patient for boron neutron capture therapy. 1 fig.

  9. Halogenated sulfidohydroboranes for nuclear medicine and boron neutron capture therapy

    DOE Patents [OSTI]

    Miura, M.; Slatkin, D.N.

    1997-08-05

    A method for performing boron neutron capture therapy for the treatment of tumors is disclosed. The method includes administering to a patient an iodinated sulfidohydroborane, a boron-10-containing compound. The site of the tumor is localized by visualizing the increased concentration of the iodine labelled compound at the tumor. The targeted tumor is then irradiated with a beam of neutrons having an energy distribution effective for neutron capture. Destruction of the tumor occurs due to high LET particle irradiation of the tissue secondary to the incident neutrons being captured by the boron-10 nuclei. Iodinated sulfidohydroboranes are disclosed which are especially suitable for the method of the invention. In a preferred embodiment, a compound having the formula Na{sub 4}B{sub 12}I{sub 11}SSB{sub 12}I{sub 11}, or another pharmaceutically acceptable salt of the compound, may be administered to a cancer patient for boron neutron capture therapy. 1 fig.

  10. Halogenated sulfidohydroboranes for nuclear medicine and boron neutron capture therapy

    DOE Patents [OSTI]

    Miura, Michiko (Hampton Bays, NY); Slatkin, Daniel N. (Southold, NY)

    1997-08-05

    A method for performing boron neutron capture therapy for the treatment of tumors is disclosed. The method includes administering to a patient an iodinated sulfidohydroborane, a boron-10-containing compound. The site of the tumor is localized. by visualizing the increased concentration of the iodine labelled compound at the tumor. The targeted tumor is then irradiated with a beam of neutrons having an energy distribution effective for neutron capture. Destruction of the tumor occurs due to high LET particle irradiation of the tissue secondary to the incident neutrons being captured by the boron-10 nuclei. Iodinated sulfidohydroboranes are disclosed which are especially suitable for the method of the invention. In a preferred embodiment, a compound having the formula Na.sub.4 B.sub.12 I.sub.11 SSB.sub.12 I.sub.11, or another pharmaceutically acceptable salt of the compound, may be administered to a cancer patient for boron neutron capture therapy.

  11. Halogenated sulfidohydroboranes for nuclear medicine and boron neutron capture therapy

    DOE Patents [OSTI]

    Miura, M.; Slatkin, D.N.

    1997-03-18

    A method for performing boron neutron capture therapy for the treatment of tumors is disclosed. The method includes administering to a patient an iodinated sulfidohydroborane, a boron-10-containing compound. The site of the tumor is localized by visualizing the increased concentration of the iodine labelled compound at the tumor. The targeted tumor is then irradiated with a beam of neutrons having an energy distribution effective for neutron capture. Destruction of the tumor occurs due to high LET particle irradiation of the tissue secondary to the incident neutrons being captured by the boron-10 nuclei. Iodinated sulfidohydroboranes are disclosed which are especially suitable for the method of the invention. In a preferred embodiment, a compound having the formula Na{sub 4}B{sub 12}I{sub 11}SSB{sub 12}I{sub 11}, or another pharmaceutically acceptable salt of the compound, may be administered to a cancer patient for boron neutron capture therapy. 1 fig.

  12. Halogenated sulfidohydroboranes for nuclear medicine and boron neutron capture therapy

    DOE Patents [OSTI]

    Miura, Michiko (Hampton Bays, NY); Slatkin, Daniel N. (Southold, NY)

    1997-03-18

    A method for performing boron neutron capture therapy for the treatment of tumors is disclosed. The method includes administering to a patient an iodinated sulfidohydroborane, a boron-10-containing compound. The site of the tumor is localized by visualizing the increased concentration of the iodine labelled compound at the tumor. The targeted tumor is then irradiated with a beam of neutrons having an energy distribution effective for neutron capture. Destruction of the tumor occurs due to high LET particle irradiation of the tissue secondary to the incident neutrons being captured by the boron-10 nuclei. Iodinated sulfidohydroboranes are disclosed which are especially suitable for the method of the invention. In a preferred embodiment, a compound having the formula Na.sub.4 B.sub.12 I.sub.11 SSB.sub.12 I.sub.11, or another pharmaceutically acceptable salt of the compound, may be administered to a cancer patient for boron neutron capture therapy.

  13. Development of a fast neutron therapy beam placement film technique 

    E-Print Network [OSTI]

    Baron, Robert Layton

    1971-01-01

    , producing a recoiling neutron; and (3) evaporation of neutrons (23). All three processes contribute to a total neutron yield estimated to be about 4 x 10 11 neutrons per microcoulomb of deuteron current (23). An actual measurement has not been made.... 55 REFERENCES 1. The Ameri. can Peoples Encyclopedia, 4, pg. 203, Grolier Incorporated, New York, 1969. 2. J. P. Barton, Some possibilities of neutron radiography. ~Ph s. Med. Biol. , 9, 33-42 (1964). 3. R. S. Stone, Neutron therapy and specific...

  14. Prototype demonstration of radiation therapy planning code system

    SciTech Connect (OSTI)

    Little, R.C.; Adams, K.J.; Estes, G.P.; Hughes, L.S. III; Waters, L.S.

    1996-09-01

    This is the final report of a one-year, Laboratory-Directed Research and Development project at the Los Alamos National Laboratory (LANL). Radiation therapy planning is the process by which a radiation oncologist plans a treatment protocol for a patient preparing to undergo radiation therapy. The objective is to develop a protocol that delivers sufficient radiation dose to the entire tumor volume, while minimizing dose to healthy tissue. Radiation therapy planning, as currently practiced in the field, suffers from inaccuracies made in modeling patient anatomy and radiation transport. This project investigated the ability to automatically model patient-specific, three-dimensional (3-D) geometries in advanced Los Alamos radiation transport codes (such as MCNP), and to efficiently generate accurate radiation dose profiles in these geometries via sophisticated physics modeling. Modem scientific visualization techniques were utilized. The long-term goal is that such a system could be used by a non-expert in a distributed computing environment to help plan the treatment protocol for any candidate radiation source. The improved accuracy offered by such a system promises increased efficacy and reduced costs for this important aspect of health care.

  15. Ivor J. Benjamin Viewing a Stressful Episode of ER : Is ATF6 the Triage Nurse?

    E-Print Network [OSTI]

    Glembotski, Christopher

    milieu remain among the most enigmatic and fundamental questions in contemporary cardiovascular biol- ogy heart disease remains a major public health problem. If prompt therapy is delayed, myocardial injury

  16. Implementation of Remote 3-Dimensional Image Guided Radiation Therapy Quality Assurance for Radiation Therapy Oncology Group Clinical Trials

    SciTech Connect (OSTI)

    Cui Yunfeng; Galvin, James M.; Radiation Therapy Oncology Group, American College of Radiology, Philadelphia, Pennsylvania ; Parker, William; Breen, Stephen; Yin Fangfang; Cai Jing; Papiez, Lech S.; Li, X. Allen; Bednarz, Greg; Chen Wenzhou; Xiao Ying

    2013-01-01

    Purpose: To report the process and initial experience of remote credentialing of three-dimensional (3D) image guided radiation therapy (IGRT) as part of the quality assurance (QA) of submitted data for Radiation Therapy Oncology Group (RTOG) clinical trials; and to identify major issues resulting from this process and analyze the review results on patient positioning shifts. Methods and Materials: Image guided radiation therapy datasets including in-room positioning CT scans and daily shifts applied were submitted through the Image Guided Therapy QA Center from institutions for the IGRT credentialing process, as required by various RTOG trials. A centralized virtual environment is established at the RTOG Core Laboratory, containing analysis tools and database infrastructure for remote review by the Physics Principal Investigators of each protocol. The appropriateness of IGRT technique and volumetric image registration accuracy were evaluated. Registration accuracy was verified by repeat registration with a third-party registration software system. With the accumulated review results, registration differences between those obtained by the Physics Principal Investigators and from the institutions were analyzed for different imaging sites, shift directions, and imaging modalities. Results: The remote review process was successfully carried out for 87 3D cases (out of 137 total cases, including 2-dimensional and 3D) during 2010. Frequent errors in submitted IGRT data and challenges in the review of image registration for some special cases were identified. Workarounds for these issues were developed. The average differences of registration results between reviewers and institutions ranged between 2 mm and 3 mm. Large discrepancies in the superior-inferior direction were found for megavoltage CT cases, owing to low spatial resolution in this direction for most megavoltage CT cases. Conclusion: This first experience indicated that remote review for 3D IGRT as part of QA for RTOG clinical trials is feasible and effective. The magnitude of registration discrepancy between institution and reviewer was presented, and the major issues were investigated to further improve this remote evaluation process.

  17. LEARNING TO COMBINE DECISIONS FROM MULTIPLE MAMMOGRAPHY VIEWS Alan Joseph Bekker

    E-Print Network [OSTI]

    Goldberger, Jacob

    describe a two-step classification method that is based on a view-level decision, implemented by a logistic model. Our method was evaluated on a standardized digital database for screening mammography (DDSM views. Index Terms-- Mammography, Microcalcifications, Computer-aided diagnosis 1. INTRODUCTION

  18. Prairie View A&M University Whole Campus Energy Report Update 

    E-Print Network [OSTI]

    Haberl, J. S.; Claridge, D. E.; Turner, W. D.

    1992-01-01

    Prairie View A&M University started a large scale energy management program in 1987 and 1988. This updated report presents an analysis of whole-campus energy consumption at the Prairie View A&M Campus where whole-campus indices were developed...

  19. Model-Based Multi-view Fusion of Cinematic Flow and Optical Imaging

    E-Print Network [OSTI]

    Paragios, Nikos

    Model-Based Multi-view Fusion of Cinematic Flow and Optical Imaging Mickael Savinaud1,2,3 , Martin-view Fusion of Cinematic Flow and Optical Imaging 669 optical imaging devices are now able to image does not enable cinematic acquisition. The use of temporal information involves either animal tracking

  20. Reconstructions in limited-view thermoacoustic tomography Yuan Xu and Lihong V. Wanga)

    E-Print Network [OSTI]

    Kuchment, Peter

    Reconstructions in limited-view thermoacoustic tomography Yuan Xu and Lihong V. Wanga) Optical for publication 9 December 2003; published 11 March 2004 The limited-view problem is studied for thermoacoustic of Physicists in Medicine. DOI: 10.1118/1.1644531 Key words: thermoacoustic tomography, photoacoustic tomography

  1. ROBUST AND UNBIASED FOREGROUND / BACKGROUND ENERGY FOR MULTI-VIEW STEREO

    E-Print Network [OSTI]

    Wong, Kenneth K.Y.

    maps even in the absence of the photo-consistency energy. To the best of our #12;knowledgeROBUST AND UNBIASED FOREGROUND / BACKGROUND ENERGY FOR MULTI-VIEW STEREO Zhihu Chen and Kwan-Yee K@cs.hku.hk, kykwong@cs.hku.hk Keywords: Multi-View Stereo, Photo-Consistency Energy, Foreground / Background Energy

  2. The Implementation of Mobile Bank Usage from marketing point of view of bank managers in Jordan.

    E-Print Network [OSTI]

    The Implementation of Mobile Bank Usage from marketing point of view of bank managers in Jordan. The study aims at determine the effect of the implementation of Mobile Bank Usage from marketing point between the Implementation of Mobile Bank Usage from marketing point of view of bank managers in Jordan

  3. LabVIEW and G as a Computing Language Course Mukkai Krishnamoorthy and Sibylle Schupp,

    E-Print Network [OSTI]

    Bystroff, Chris

    VIEW project. We have to calculate the (stops shortly) g.c.d. of two numbers. (Sighs.) LabVIEW is a cool:=a; return || Figure 1: Greatest Common Divisor Algorithm Ms. Engi Neer: This is cool. I remember my CS­1 understand the algorithm I can start my programming. Here is my front panel. (Opens a new front panel

  4. LabVIEW and G as a Computing Language Course Mukkai Krishnamoorthy and Sibylle Schupp,

    E-Print Network [OSTI]

    Bystroff, Chris

    VIEW project. We have to calculate the (stops shortly) g.c.d. of two numbers. (Sighs.) LabVIEW is a cool:=a; return || Figure 1: Greatest Common Divisor Algorithm Ms. Engi Neer: This is cool. I remember my CS-1 understand the algorithm I can start my programming. Here is my front panel. (Opens a new front panel

  5. You are here: Home / News / 3D view of 1D nanostructures More services

    E-Print Network [OSTI]

    Espinosa, Horacio D.

    create tool to put the lid on solar power fluctuations Variability law for solar panels News 3D view of 1You are here: Home / News / 3D view of 1D nanostructures Share More services Related Links of nanogenerators based on GaN nanowires, for powering of self-powered nanodevices. This story is reprinted from

  6. Design and Selection of Materialized Views in a Data Warehousing Environment: A Case Study

    E-Print Network [OSTI]

    Song, Il-Yeol

    , including query access frequencies, base-data update frequencies, query access costs, view maintenance costs views, the total cost of the maintenance, storage and query processing of the system is optimized incur a high maintenance cost. Furthermore, for a system with limited storage space and

  7. An Analysis of Document Viewing Patterns of Web Search Engine Users

    E-Print Network [OSTI]

    Jansen, James

    the concepts of Web results page and Web page viewing patterns by users of Web search engines. It presents for Web usage mining. The authors also present the results of a temporal of analysis of Web page viewing how users interact with Web search engines. There are also reports on the number of result pages

  8. The Universe Viewed in Gamma-Rays 1 Properties of Gamma-ray Bursts Localized by

    E-Print Network [OSTI]

    Enomoto, Ryoji

    The Universe Viewed in Gamma-Rays 1 Properties of Gamma-ray Bursts Localized by the HETE-2 and localize Gamma-ray bursts (GRBs) in wide field of view. HETE-2 have been localized about 20 GRBs per year hours after the burst. 1. The High Energy Transient Explorer 2 Gamma-ray burst (GRB) is the most

  9. MedView: A Declarative Approach to Evidence-Based Medicine

    E-Print Network [OSTI]

    Torgersson, Olof

    MedView: A Declarative Approach to Evidence-Based Medicine Göran Falkman Department of Computer Abstract. MedView is a project that meets the challenges of evidence-based oral medicine by providing", John Naisbitt exclaimed in 1982 [1]. This is perhaps particularly true for clinical medicine

  10. Painting Objects with View-dependent Effects Cindy M. Grimm, Michael Kowalski

    E-Print Network [OSTI]

    Grimm, Cindy

    Painting Objects with View-dependent Effects Cindy M. Grimm, Michael Kowalski Washington Univ. in St. Louis Abstract We present a system for painting on an object in a view-dependent way. The user creates paintings of the object from various camera positions to produce a texture map which changes

  11. Materialized Views in Probabilistic Databases For Information Exchange and Query Optimization

    E-Print Network [OSTI]

    Thrun, Sebastian

    probabilistic data contain correlations between tuples, and the current approach is to capture these correla (BID) table. Not all views can be rep- resented as BID tables and so we propose a novel partial processing on probabilistic data, we can ignore the lineage and use materialized views to more efficiently

  12. TU-C-BRE-04: 3D Gel Dosimetry Using ViewRay On-Board MR Scanner: A Feasibility Study

    SciTech Connect (OSTI)

    Zhang, L; Du, D; Green, O; Rodriguez, V; Wooten, H; Xiao, Z; Yang, D; Hu, Y; Li, H

    2014-06-15

    Purpose: MR based 3D gel has been proposed for radiation therapy dosimetry. However, access to MR scanner has been one of the limiting factors for its wide acceptance. Recent commercialization of an on-board MR-IGRT device (ViewRay) may render the availability issue less of a concern. This work reports our attempts to simulate MR based dose measurement accuracy on ViewRay using three different gels. Methods: A spherical BANG gel dosimeter was purchased from MGS Research. Cylindrical MAGIC gel and Fricke gel were fabricated in-house according to published recipes. After irradiation, BANG and MAGIC were imaged using a dual-echo spin echo sequence for T2 measurement on a Philips 1.5T MR scanner, while Fricke gel was imaged using multiple spin echo sequences. Difference between MR measured and TPS calculated dose was defined as noise. The noise power spectrum was calculated and then simulated for the 0.35 T magnetic field associated with ViewRay. The estimated noise was then added to TG-119 test cases to simulate measured dose distributions. Simulated measurements were evaluated against TPS calculated doses using gamma analysis. Results: Given same gel, sequence and coil setup, with a FOV of 180×90×90 mm3, resolution of 3×3×3 mm3, and scanning time of 30 minutes, the simulated measured dose distribution using BANG would have a gamma passing rate greater than 90% (3%/3mm and absolute). With a FOV 180×90×90 mm3, resolution of 4×4×5 mm3, and scanning time of 45 minutes, the simulated measuremened dose distribution would have a gamma passing rate greater than 97%. MAGIC exhibited similar performance while Fricke gel was inferior due to much higher noise. Conclusions: The simulation results demonstrated that it may be feasible to use MAGIC and BANG gels for 3D dose verification using ViewRay low-field on-board MRI scanner.

  13. System and method for delivery of neutron beams for medical therapy

    DOE Patents [OSTI]

    Nigg, David W. (Idaho Falls, ID); Wemple, Charles A. (Idaho Falls, ID)

    1999-01-01

    A neutron delivery system that provides improved capability for tumor control during medical therapy. The system creates a unique neutron beam that has a bimodal or multi-modal energy spectrum. This unique neutron beam can be used for fast-neutron therapy, boron neutron capture therapy (BNCT), or both. The invention includes both an apparatus and a method for accomplishing the purposes of the invention.

  14. Metalloporphyrins and their uses as imageable tumor-targeting agents for radiation therapy

    DOE Patents [OSTI]

    Miura, Michiko; Slatkin, Daniel N.

    2003-05-20

    The present invention covers halogenated derivatives of boronated porphyrins containing multiple carborane cages having the formula ##STR1## which selectively accumulate in neoplastic tissue within the irradiation volume and thus can be used in cancer therapies including, but not limited to, boron neutron- capture therapy and photodynamic therapy. The present invention also covers methods for using these halogenated derivatives of boronated porphyrins in tumor imaging and cancer treatment.

  15. Use of novel metalloporphyrins as imageable tumor-targeting agents for radiation therapy

    DOE Patents [OSTI]

    Miura, Michiko; Slatkin, Daniel N.

    2005-10-04

    The present invention covers halogenated derivatives of boronated phorphyrins containing multiple carborane cages having the formula ##STR1## which selectively accumulate in neoplastic tissue within the irradiation volume and thus can be used in cancer therapies including, but not limited to, boron neutron-capture therapy and photodynamic therapy. The present invention also covers methods for using these halogenated derivatives of boronated porphyrins in tumor imaging and cancer treatment.

  16. System and method for delivery of neutron beams for medical therapy

    DOE Patents [OSTI]

    Nigg, D.W.; Wemple, C.A.

    1999-07-06

    A neutron delivery system that provides improved capability for tumor control during medical therapy is disclosed. The system creates a unique neutron beam that has a bimodal or multi-modal energy spectrum. This unique neutron beam can be used for fast-neutron therapy, boron neutron capture therapy (BNCT), or both. The invention includes both an apparatus and a method for accomplishing the purposes of the invention. 5 figs.

  17. Optic for an endoscope/borescope having high resolution and narrow field of view

    DOE Patents [OSTI]

    Stone, Gary F.; Trebes, James E.

    2003-10-28

    An optic having optimized high spatial resolution, minimal nonlinear magnification distortion while at the same time having a limited chromatic focal shift or chromatic aberrations. The optic located at the distal end of an endoscopic inspection tool permits a high resolution, narrow field of view image for medical diagnostic applications, compared to conventional optics for endoscopic instruments which provide a wide field of view, low resolution image. The image coverage is over a narrow (<20 degrees) field of view with very low optical distortion (<5% pin cushion or barrel distortion. The optic is also optimized for best color correction as well as to aid medical diagnostics.

  18. The Therapeutic Alliance in Cognitive-Behavioral Therapy for Children with Autism and Anxiety

    E-Print Network [OSTI]

    Klebanoff, Sami

    2015-01-01

    in Cognitive-Behavioral Therapy for Children with Autism andAnxiety Autism spectrum disorders (ASD) are lifelongHigh-Functioning Adolescents With Autism Spectrum Disorders.

  19. Novel Approaches to Breast Cancer Therapy: Evaluation of Next Generation Dendrimers for Drug Delivery 

    E-Print Network [OSTI]

    Snow, Merideth

    2010-07-14

    concentrations while dendrimers F4-1 and F2-1 were not. The dendrimer compounds may represent the future of breast cancer therapy....

  20. Autologous stromal vascular fraction therapy for rheumatoid arthritis: rationale and clinical safety

    E-Print Network [OSTI]

    2012-01-01

    cell therapy for multiple sclerosis. J Translational Med+ regulatory T cells in multiple sclerosis. Ann Neurol 2010,of relapsing- remitting multiple sclerosis patients. Hum

  1. Safety evaluation of allogeneic umbilical cord blood mononuclear cell therapy for degenerative conditions

    E-Print Network [OSTI]

    2010-01-01

    cell therapy for multiple sclerosis. J Transl Med 2009, 7:19 patients had multiple sclerosis, 12 patients hadParaplegia Ataxia Multiple Sclerosis Amyotrophic Lateral

  2. Efficacy of Cognitive Behavioral Therapy in Treating Anorexia Nervosa: A Review of Literature

    E-Print Network [OSTI]

    Oakes, Brittany

    2014-01-01

    rates in patients with anorexia nervosa and other eatingfamily therapy for anorexia nervosa patients. EatingLohr, K. N. (2007). Anorexia nervosa treatment: A systematic

  3. Scleromyxedema secondary to hepatitis c virus and successfully treated with antiviral therapy

    E-Print Network [OSTI]

    Smith, JA; Kalimullah, FA; Erickson, CP; Peng, LS

    2015-01-01

    Therapy For Chronic Active Hepatitis C. J Am Acad Dermatol.scleromyxedema secondary to hepatitis C successfully treatedWe recommend considering hepatitis C virus when working up

  4. Mycobacterium porferae infection in a psoriasis patient on anti-tnf-a therapy

    E-Print Network [OSTI]

    Laquer, Vivian; Ta, Tuan; Nguyen, Tien; Tan, Belinda

    2013-01-01

    biologic therapy for psoriasis. J Dermatolog Treat 2012. [porferae infection in a psoriasis patient on anti-tnf-aIrvine, CA USA Introduction Psoriasis is a chronic, auto-

  5. War, Trauma, and Technologies of the Self : : The Making of Virtual Reality Exposure Therapy

    E-Print Network [OSTI]

    Brandt, Marisa Renee

    R. L. (2004). Combat Duty in Iraq and Afghanistan, Mentalservice members who served in Iraq and Afghanistan. Militaryevaluation of the Virtual Iraq/Afghanistan exposure therapy

  6. Merguerian, Charles, 1986a, Tunnel vision -A deep view of the bedrock geology of New York City (NYC).

    E-Print Network [OSTI]

    Merguerian, Charles

    Merguerian, Charles, 1986a, Tunnel vision - A deep view of the bedrock geology of New York City This Abstract: Merguerian, Charles, 1986a, Tunnel vision - A deep view of the bedrock geology of New York City

  7. On bolus for megavoltage photon and electron radiation therapy

    SciTech Connect (OSTI)

    Vyas, Vedang; Palmer, Lisa; Mudge, Ray; Jiang, Runqing; Fleck, Andre; Schaly, Bryan; Osei, Ernest; Charland, Paule

    2013-10-01

    Frequently, in radiation therapy one must treat superficial lesions on cancer patients; these are at or adjacent to the skin. Megavoltage photon radiotherapy penetrates through the skin to irradiate deep-seated tumors, with skin-sparing property. Hence, to treat superficial lesions, one must use a layer of scattering material to feign as the skin surface. Although megavoltage electron beams are used for superficial treatments, one occasionally needs to enhance the dose near the surface. Such is the function of a “bolus,” a natural or synthetically developed material that acts as a layer of tissue to provide a more effective treatment to the superficial lesions. Other uses of boluses are to correct for varying surface contours and to add scattering material around the patient's surface. Materials used as bolus vary from simple water to metal and include various mixtures and compounds. Even with the modernization of the technology for external-beam therapy and the emergence of various commercial boluses, the preparation and utilization of a bolus in clinical radiotherapy remains an art. Considering the varying experiences and practices, this paper briefly summarizes available boluses that have been proposed and are employed in clinical radiotherapy. Although this review is not exhaustive, it provides some initial guidance and answers questions that may arise in clinical practice.

  8. Proton therapy construction projects in the United States

    SciTech Connect (OSTI)

    Alonso, J.R.

    1992-11-01

    Proton and heavy-ion radiation therapy has been taking place now for 40 years, at many accelerator laboratories around the world, essentially all of these centers built originally for physics research. The high degree of promise shown for using these particles for treating and curing cancer has stimulated the medical community to look seriously at building dedicated accelerator facilities in a hospital setting, where more rapid progress can be made in clinical research, and development of effective treatments with these beams. In the United States, the first such facility, at the Loma Linda University Medical Center, has been in operation now for two years, and is currently treating a total of 35 to 40 patients per day. Two new projects are being designed at present, one at the Massachusetts General Hospital in Boston, Massachusetts, the second a joint project of the Lawrence Berkeley Laboratory and the University of California at Davis Medical Center in Sacramento, California. This paper will discuss accelerator and beam characteristics relevant to the proton-therapy application, and will present performance and operations characteristics for the Loma Linda facility, as well as details of the plans, process and progress towards construction of the new facilities in Boston and Sacramento.

  9. Jefferson Lab scientist puts intriguing view on spin of the proton...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    scientist puts intriguing view on spin of the proton April 17, 2007 Newport News, Va. - A new result from the HERMES experiment at The German Electron Synchrotron DESY indicates...

  10. Computing point-of-view : modeling and simulating judgments of taste

    E-Print Network [OSTI]

    Liu, Xinyu Hugo, 1979-

    2006-01-01

    People have rich points-of-view that afford them the ability to judge the aesthetics of people, things, and everyday happenstance; yet viewpoint has an ineffable quality that is hard to articulate in words, let alone capture ...

  11. NATURE NANOTECHNOLOGY | VOL 9 | JANUARY 2014 | www.nature.com/naturenanotechnology 11 news & views

    E-Print Network [OSTI]

    NATURE NANOTECHNOLOGY | VOL 9 | JANUARY 2014 | www.nature.com/naturenanotechnology 11 news & views Nanotechnology, Andrew Turberfield and colleagues at the University of Oxford and Warwick Medical School now show

  12. The Impact of the CEO's View of Risk on Turnover and the Value of Equity 

    E-Print Network [OSTI]

    Campbell, Timothy Colin

    2011-10-21

    Recent theory predicts that two factors influencing the CEO’s view of risk, overconfidence and debt-like compensation, have implications for CEO forced turnover and firm equity value, respectively. We test each of these ...

  13. Managing Applicants Reference Guide Quick easy steps of Viewing Applications and Changing Workflow States

    E-Print Network [OSTI]

    Powers, Robert

    Change* Within a search only the hiring managers assigned to that requisition, or EAD Users and HR Users may change workflow states. Hiring managers actionsManaging Applicants Reference Guide Quick easy steps of Viewing Applications

  14. 176 nature nanotechnology | VOL 5 | MARCH 2010 | www.nature.com/naturenanotechnology news & views

    E-Print Network [OSTI]

    Buratto, Steve

    176 nature nanotechnology | VOL 5 | MARCH 2010 | www.nature.com/naturenanotechnology news & views P humidity. Writing in Nature Nanotechnology, Saeed Moghaddam, Mark Shannon and colleagues1 at the University

  15. DOE Solicits Views on the Implementation of Large-Capacity Clothes...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Large-Capacity Clothes Washer Waivers DOE Solicits Views on the Implementation of Large-Capacity Clothes Washer Waivers November 30, 2010 - 10:56am Addthis The Department of...

  16. A manual procedure for assembly sequence planning based on the exploded view method 

    E-Print Network [OSTI]

    Rivero, Andres R

    1995-01-01

    This thesis covers the development of a manual planning procedure based on the computerized method of exploded views to generate an optimal or near-optimal assembly sequence. Care has been taken to minimize iterative and ...

  17. A State Regulator's View of 'PURPA' And Its Impact on Energy Conservation in the Industrial Sector 

    E-Print Network [OSTI]

    Williams, M. L.

    1981-01-01

    The purpose of my comments this afternoon is to share with you my views concerning the status of the Public Utility Regulatory Policies Act (PURPA), and how some of the rate standards contained in the Act may affect energy conservation...

  18. GPU-based Scalable Volumetric Reconstruction for Multi-view Stereo

    SciTech Connect (OSTI)

    Kim, H; Duchaineau, M; Max, N

    2011-09-21

    We present a new scalable volumetric reconstruction algorithm for multi-view stereo using a graphics processing unit (GPU). It is an effectively parallelized GPU algorithm that simultaneously uses a large number of GPU threads, each of which performs voxel carving, in order to integrate depth maps with images from multiple views. Each depth map, triangulated from pair-wise semi-dense correspondences, represents a view-dependent surface of the scene. This algorithm also provides scalability for large-scale scene reconstruction in a high resolution voxel grid by utilizing streaming and parallel computation. The output is a photo-realistic 3D scene model in a volumetric or point-based representation. We demonstrate the effectiveness and the speed of our algorithm with a synthetic scene and real urban/outdoor scenes. Our method can also be integrated with existing multi-view stereo algorithms such as PMVS2 to fill holes or gaps in textureless regions.

  19. A View of Manufacturing Through 3D Glasses | GE Global Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    a.m. Eastern Time, I will be moderating a Google+ Video Hangout with top experts in the additive manufacturing space, which you can view on GE Global Research Live. I will be...

  20. Student Course Survey Reports How to view your SCS reports in PeopleSoft

    E-Print Network [OSTI]

    Stoiciu, Mihai

    1 Student Course Survey Reports How to view your SCS reports in PeopleSoft Your current and past SCS reports are now available to you through the Williams Student Records system. SCS quantitative reports are no longer printed

  1. Ecology in Africa: a view from the past for informing the future

    E-Print Network [OSTI]

    Martins, Dino J.

    2013-01-01

    ISSN 1948?6596  Ecology in Africa: a view from the past for http://www.springer.com/  “Africa’s  natural  habitats  are the  ecology  of  Africa…”.   These opening sentences from 

  2. Transmission System Expansion Plans in View Point of Deterministic, Probabilistic and Security Reliability Criteria

    E-Print Network [OSTI]

    Transmission System Expansion Plans in View Point of Deterministic, Probabilistic and Security reliability criterion, probabilistic reliability criterion and security criterion based on N- contingency control system as well as reasonable strength of grid originally. Because investment for power system

  3. Cellulosic Biofuels: Expert Views on Prospects for Advancement and Jeffrey Keisler

    E-Print Network [OSTI]

    Massachusetts at Amherst, University of

    Cellulosic Biofuels: Expert Views on Prospects for Advancement Erin Baker and Jeffrey Keisler funding and the likelihood of achieving advances in cellulosic biofuel technologies. While in collecting more information on this technology. Keywords: Biofuels; Technology R&D; Uncertainty

  4. Headteachers’ views on the inclusion of students with special educational needs in Taiwan 

    E-Print Network [OSTI]

    Chang, Chia-Wen

    2011-07-04

    The main aim of this research is to offer a sociological analysis of Taiwanese headteachers’ views of the inclusion of students with special educational needs (SEN) in mainstream schools. Taiwan is a country which combines ...

  5. Intrinsic modulation of ENSO predictability viewed through a local Lyapunov lens

    E-Print Network [OSTI]

    Wittenberg, Andrew

    Intrinsic modulation of ENSO predictability viewed through a local Lyapunov lens Christina magnitude, frequency, and physical evolution. Local Lyapunov exponents (LLEs) estimated from the monthly Predictability Á Local Lyapunov exponents 1 Introduction The limits of predictability of the state

  6. Wide Field of View Compressive Light Field Display using a Multilayer Architecture and Tracked Viewers

    E-Print Network [OSTI]

    Maimone, Andrew

    In this paper, we discuss a simple extension to existing compressive multilayer light field displays that greatly extends their field of view and depth of field. Rather than optimizing these displays to create a moderately ...

  7. Automated Deduction: A Technological Point of View Peter Baumgartner, Ingo Dahn, Jrgen Dix, Ulrich Furbach,

    E-Print Network [OSTI]

    Baumgartner, Peter

    1 Automated Deduction: A Technological Point of View Peter Baumgartner, Ingo Dahn, Jürgen Dix called ILF, developed by I. Dahn within the German focus program on Deduction, was able to translate

  8. View the archive at http://blogs. nature.com/nature/journalclub

    E-Print Network [OSTI]

    Conrad, Clint

    View the archive at http://blogs. nature.com/nature/journalclub Petr Svoboda Institute of Molecular of Standards and Technology in Gaithersburg, Maryland, and her team probed the three-dimensional magnetic

  9. California’s Energy Future: The View to 2050 - Summary Report

    E-Print Network [OSTI]

    Yang, Christopher

    2011-01-01

    View to 2050 Laser Fusion Energy a Potential Game Changerworld leader in laser fusion energy—a potential game changera Laser Inertial Fusion Energy (LIFE) power plant would be

  10. UFilter: A Lightweight XML View Update Checker Ling Wang, Elke A. Rundensteiner and Murali Mani

    E-Print Network [OSTI]

    U­Filter: A Lightweight XML View Update Checker Ling Wang, Elke A. Rundensteiner and Murali Mani 1997 year Simon & Schuster Inc. A02 Prentice­Hall Inc. B01 McGraw­Hill

  11. nature methods | VOL.7 NO.7 | JULY 2010 | 505 news and views

    E-Print Network [OSTI]

    Cai, Long

    of the fly's teth- ered flight. They found that active flying (as opposed to passive viewing) altered data and ablation studies in larger flies, including house flies and blow flies, has identified neurons

  12. DOE Zero Energy Ready Home Case Study: Clifton View Homes, Marine...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Marine Drive and Port Hadlcok, Coupeville and Port Hadlock WA DOE Zero Energy Ready Home Case Study: Clifton View Homes, Marine Drive and Port Hadlcok, Coupeville and Port Hadlock...

  13. Installing and Using VMWare View Client for Windows This document describes how to get up and running with View if you use a Windows

    E-Print Network [OSTI]

    Neirotti, Juan Pablo

    to carry out the installation steps once per device. 1. Go to VMWare View and download the relevant install will need to delete and re type. #12;4 3. Once you have clicked Connect, you will be prompted to enter your defaults, such as your Outlook signature, any Internet browser favourites etc. These will be saved

  14. Interactions of tropical synoptic-scale features as viewed from satellite 

    E-Print Network [OSTI]

    Winton, Susan Elizabeth

    1991-01-01

    INTERACTIONS OF TROPICAL SYNOPTIC-SCALE FEATURES AS VIEWED FROM SATELLITE Thesis by SUSAN ELIZABETH WINTON Submitted to tbe Office of Graduate Studies of Texas ARM University in partial fulfillment of the requirements for the degree... of MASTER OF SCIENCE December 1991 Major Subject: Meteorology INTERACTIONS QF TROPICAL SYNOPTIC-SCALE FEATURES AS VIEWED FROM SATELLITE A Thesis by SUSAN ELIZABETH WINTON Approved as to style and content by: James P. McGuirk (Chair of Committee...

  15. The pharmaco-economics of combination therapies : a study of the effects of component and market factors on combined therapy price

    E-Print Network [OSTI]

    Subramaniam, Sundar

    2006-01-01

    For a growing number of indications, combination therapies are becoming increasingly common due in part to their superior efficacy, as compared to monotherapies. In fact, in the case of infectious diseases such as AIDS and ...

  16. Improving superficial target delineation in radiation therapy with endoscopic tracking and registration

    SciTech Connect (OSTI)

    Weersink, R. A.; Qiu, J.; Hope, A. J.; Daly, M. J.; Cho, B. C. J.; DaCosta, R. S.; Sharpe, M. B.; Breen, S. L.; Chan, H.; Jaffray, D. A.

    2011-12-15

    Purpose: Target delineation within volumetric imaging is a critical step in the planning process of intensity modulated radiation therapy. In endoluminal cancers, endoscopy often reveals superficial areas of visible disease beyond what is seen on volumetric imaging. Quantitatively relating these findings to the volumetric imaging is prone to human error during the recall and contouring of the target. We have developed a method to improve target delineation in the radiation therapy planning process by quantitatively registering endoscopic findings contours traced on endoscopic images to volumetric imaging. Methods: Using electromagnetic sensors embedded in an endoscope, 2D endoscopic images were registered to computed tomography (CT) volumetric images by tracking the position and orientation of the endoscope relative to a CT image set. Regions-of-interest (ROI) in the 2D endoscopic view were delineated. A mesh created within the boundary of the ROI was projected onto the 3D image data, registering the ROI with the volumetric image. This 3D ROI was exported to clinical radiation treatment planning software. The precision and accuracy of the procedure was tested on two solid phantoms with superficial markings visible on both endoscopy and CT images. The first phantom was T-shaped tube with X-marks etched on the interior. The second phantom was an anatomically correct skull phantom with a phantom superficial lesion placed on the pharyngeal surface. Markings were contoured on the endoscope images and compared with contours delineated in the treatment planning system based on the CT images. Clinical feasibility was tested on three patients with early stage glottic cancer. Image-based rendering using manually identified landmarks was used to improve the registration. Results: Using the T-shaped phantom with X-markings, the 2D to 3D registration accuracy was 1.5-3.5 mm, depending on the endoscope position relative to the markings. Intraobserver standard variation was 0.5 mm. Rotational accuracy was within 2 deg. Using the skull phantom, registration accuracy was assessed by calculating the average surface minimum distance between the endoscopy and treatment planning contours. The average surface distance was 0.92 mm with 93% of all points in the 2D-endoscopy ROI within 1.5 mm of any point within the ROI contoured in the treatment planning software. This accuracy is limited by the CT imaging resolution and the electromagnetic (EM) sensor accuracy. The clinical testing demonstrated that endoscopic contouring is feasible. With registration based on em tracking only, accuracy was 5.6-8.4 mm. Image-based registration reduced this error to less than 3.5 mm and enabled endoscopic contouring in all cases. Conclusions: Registration of contours generated on 2D endoscopic images to 3D planning space is feasible, with accuracy smaller than typical set-up margins. Used in addition to standard 3D contouring methods in radiation planning, the technology may improve gross tumour volume (GTV) delineation for superficial tumors in luminal sites that are only visible in endoscopy.

  17. Department Chair, Physical Therapy BYRDINE F. LEWIS SCHOOL OF NURSING AND HEALTH PROFESSIONS

    E-Print Network [OSTI]

    Frantz, Kyle J.

    Department Chair, Physical Therapy BYRDINE F. LEWIS SCHOOL OF NURSING AND HEALTH PROFESSIONS The Department of Physical Therapy in the Byrdine F. Lewis School of Nursing and Health Professions at Georgia Committee (Log# 16028), Byrdine F. Lewis School of Nursing and Health Professions, Georgia State University

  18. Silk-based resorbable electronic devices for remotely controlled therapy and in vivo infection abatement

    E-Print Network [OSTI]

    Rogers, John A.

    Silk-based resorbable electronic devices for remotely controlled therapy and in vivo infection and integrate in the biological milieu, and technology, through the use of recently developed material platforms the necessary thermal therapy or trigger drug delivery. Such externally control- lable, resorbable devices

  19. VISTAnet: Radiation therapy treatment planning through rapid dose calculation and interactive 3D volume visualization

    E-Print Network [OSTI]

    State, Andrei

    deliver a high radiation dose to the planning target volume and a low dose to surrounding normal tissueVISTAnet: Radiation therapy treatment planning through rapid dose calculation and interactive 3D capable of real-time radiation therapy dose calculation and display. We report on the methods used

  20. A hybrid approach to beam angle optimization in intensity-modulated radiation therapy

    E-Print Network [OSTI]

    Bertsimas, Dimitris

    Linear programming Computational experiments a b s t r a c t Intensity-Modulated Radiation Therapy Optimization) is an important problem and is today often based on human experience. In this context, we faceA hybrid approach to beam angle optimization in intensity-modulated radiation therapy D. Bertsimas

  1. Parallelization of Radiation Therapy Treatment Planning(RTTP) : A Case Study

    E-Print Network [OSTI]

    Chaudhary, Vipin

    the therapy planning process by using parallel computing techniques. Skin Normal Tissues Tumor Cells Beams sensitivity of the cells irradiated * Chemical environment of cells Figure 1: Radiation therapy treatment dose dis- tribution within the patient body. A plan is a total dose dis- tribution obtained by summing

  2. Photodynamic Therapy with Motexafin Lutetium for Rectal Cancer: A Preclinical Model in the Dog

    E-Print Network [OSTI]

    Yodh, Arjun G.

    Photodynamic Therapy with Motexafin Lutetium for Rectal Cancer: A Preclinical Model in the Dog H of rectal resection after motexafin lutetium-mediated photodynamic therapy. Methods. Ten mixed breed dogs received the photosensitizing agent motexafin lutetium (MLu, Pharmacyclics, Inc., Sunnyvale, CA) of 2 mg

  3. Cyclotron Produced Radionuclides for Diagnosis and Therapy of Human Neoplasms

    SciTech Connect (OSTI)

    Steven Larson MD

    2009-09-21

    This project funded since 1986 serves as a core project for cancer research throughout MSKCC, producing key radiotracers as well as basic knowledge about thel physics of radiation decay and imaging, for nuclear medicine applications to cancer diagnosis and therapy. In recent years this research application has broadened to include experiments intended to lead to an improved understanding of cancer biology and into the discovery and testing of new cancer drugs. Advances in immune based radiotargeting form the basis for this project. Both antibody and cellular based immune targeting methods have been explored. The multi-step targeting methodologies (MST) developed by NeoRex (Seattle,Washington), have been adapted for use with positron emitting isotopes and PET allowing the quantification and optimization of targeted delivery. In addition, novel methods for radiolabeling immune T-cells with PET tracers have advanced our ability to track these cells of prolonged period of time.

  4. Measurements and simulations of focused beam for orthovoltage therapy

    SciTech Connect (OSTI)

    Abbas, Hassan; Mahato, Dip N.; Satti, Jahangir; MacDonald, C. A.

    2014-04-15

    Purpose: Megavoltage photon beams are typically used for therapy because of their skin-sparing effect. However, a focused low-energy x-ray beam would also be skin sparing, and would have a higher dose concentration at the focal spot. Such a beam can be produced with polycapillary optics. MCNP5 was used to model dose profiles for a scanned focused beam, using measured beam parameters. The potential of low energy focused x-ray beams for radiation therapy was assessed. Methods: A polycapillary optic was used to focus the x-ray beam from a tungsten source. The optic was characterized and measurements were performed at 50 kV. PMMA blocks of varying thicknesses were placed between optic and the focal spot to observe any variation in the focusing of the beam after passing through the tissue-equivalent material. The measured energy spectrum was used to model the focused beam in MCNP5. A source card (SDEF) in MCNP5 was used to simulate the converging x-ray beam. Dose calculations were performed inside a breast tissue phantom. Results: The measured focal spot size for the polycapillary optic was 0.2 mm with a depth of field of 5 mm. The measured focal spot remained unchanged through 40 mm of phantom thickness. The calculated depth dose curve inside the breast tissue showed a dose peak several centimeters below the skin with a sharp dose fall off around the focus. The percent dose falls below 10% within 5 mm of the focus. It was shown that rotating the optic during scanning would preserve the skin-sparing effect of the focused beam. Conclusions: Low energy focused x-ray beams could be used to irradiate tumors inside soft tissue within 5 cm of the surface.

  5. Hypofractionated Radiation Therapy for Breast Ductal Carcinoma In Situ

    SciTech Connect (OSTI)

    Hathout, Lara [Department of Radiation Oncology, Hôpital Maisonneuve-Rosemont, Centre affilié à l'Université de Montréal, Montreal, Quebec (Canada); Hijal, Tarek [Department of Radiation Oncology, McGill University Health Centre, Montreal, Quebec (Canada); Théberge, Valérie [Department of Radiation Oncology, Centre hospitalier universitaire de Québec, L'Hôtel-Dieu de Québec, Quebec (Canada); Centre des maladies du sein Deschênes-Fabia, Quebec (Canada); Fortin, Bernard [Department of Radiation Oncology, Hôpital Maisonneuve-Rosemont, Centre affilié à l'Université de Montréal, Montreal, Quebec (Canada); Vulpe, Horia [Department of Radiation Oncology, McGill University Health Centre, Montreal, Quebec (Canada); Hogue, Jean-Charles [Centre des maladies du sein Deschênes-Fabia, Quebec (Canada); Centre hospitalier universitaire de Québec, Hôpital St-Sacrement, Quebec (Canada); Lambert, Christine [Department of Radiation Oncology, McGill University Health Centre, Montreal, Quebec (Canada); Bahig, Houda [Department of Radiation Oncology, Hôpital Maisonneuve-Rosemont, Centre affilié à l'Université de Montréal, Montreal, Quebec (Canada); and others

    2013-12-01

    Purpose: Conventional radiation therapy (RT) administered in 25 fractions after breast-conserving surgery (BCS) is the standard treatment for ductal carcinoma in situ (DCIS) of the breast. Although accelerated hypofractionated regimens in 16 fractions have been shown to be equivalent to conventional RT for invasive breast cancer, few studies have reported results of using hypofractionated RT in DCIS. Methods and Materials: In this multicenter collaborative effort, we retrospectively reviewed the records of all women with DCIS at 3 institutions treated with BCS followed by hypofractionated whole-breast RT (WBRT) delivered in 16 fractions. Results: Between 2003 and 2010, 440 patients with DCIS underwent BCS followed by hypofractionated WBRT in 16 fractions for a total dose of 42.5 Gy (2.66 Gy per fraction). Boost RT to the surgical bed was given to 125 patients (28%) at a median dose of 10 Gy in 4 fractions (2.5 Gy per fraction). After a median follow-up time of 4.4 years, 14 patients had an ipsilateral local relapse, resulting in a local recurrence-free survival of 97% at 5 years. Positive surgical margins, high nuclear grade, age less than 50 years, and a premenopausal status were all statistically associated with an increased occurrence of local recurrence. Tumor hormone receptor status, use of adjuvant hormonal therapy, and administration of additional boost RT did not have an impact on local control in our cohort. On multivariate analysis, positive margins, premenopausal status, and nuclear grade 3 tumors had a statistically significant worse local control rate. Conclusions: Hypofractionated RT using 42.5 Gy in 16 fractions provides excellent local control for patients with DCIS undergoing BCS.

  6. Feasibility of a predictive model of Hsp70b-activated gene therapy protein expression during ultrasound hyperthermia

    E-Print Network [OSTI]

    Silcox, Christina Elise

    2014-01-01

    Gene therapy has been heralded as a possible approach to a variety of diseases and conditions, ranging from cancer and heart disease to blindness and neurodegenerative diseases. However, progress in gene therapy requires ...

  7. Pathologic and biologic response to preoperative endocrine therapy in patients with ER-positive ductal carcinoma in situ

    E-Print Network [OSTI]

    2009-01-01

    and the effect of neoadju- vant hormone therapy in thefor DCIS. The neoadju- vant approach described in our study

  8. Evaluation of fracture risk and potential drug holidays for postmenopausal women on long-term bisphosphonate therapy

    E-Print Network [OSTI]

    Kostoff, Matthew D.; Saseen, Joseph J.; Borgelt, Laura M.

    2014-04-28

    or discontinuation. These data emphasize the need to accurately assess risk and benefit in patients treated with bisphosphonate therapy....

  9. Nomograms Predicting Response to Therapy and Outcomes After Bladder-Preserving Trimodality Therapy for Muscle-Invasive Bladder Cancer

    SciTech Connect (OSTI)

    Coen, John J., E-mail: jcoen@harthosp.org [Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts (United States); Paly, Jonathan J.; Niemierko, Andrzej [Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts (United States)] [Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts (United States); Kaufman, Donald S. [Department of Medical Oncology, Massachusetts General Hospital, Boston, Massachusetts (United States)] [Department of Medical Oncology, Massachusetts General Hospital, Boston, Massachusetts (United States); Heney, Niall M. [Department of Urology, Massachusetts General Hospital, Boston, Massachusetts (United States)] [Department of Urology, Massachusetts General Hospital, Boston, Massachusetts (United States); Spiegel, Daphne Y.; Efstathiou, Jason A.; Zietman, Anthony L.; Shipley, William U. [Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts (United States)] [Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts (United States)

    2013-06-01

    Purpose: Selective bladder preservation by use of trimodality therapy is an established management strategy for muscle-invasive bladder cancer. Individual disease features have been associated with response to therapy, likelihood of bladder preservation, and disease-free survival. We developed prognostic nomograms to predict the complete response rate, disease-specific survival, and likelihood of remaining free of recurrent bladder cancer or cystectomy. Methods and Materials: From 1986 to 2009, 325 patients were managed with selective bladder preservation at Massachusetts General Hospital (MGH) and had complete data adequate for nomogram development. Treatment consisted of a transurethral resection of bladder tumor followed by split-course chemoradiation. Patients with a complete response at midtreatment cystoscopic assessment completed radiation, whereas those with a lesser response underwent a prompt cystectomy. Prognostic nomograms were constructed predicting complete response (CR), disease-specific survival (DSS), and bladder-intact disease-free survival (BI-DFS). BI-DFS was defined as the absence of local invasive or regional recurrence, distant metastasis, bladder cancer-related death, or radical cystectomy. Results: The final nomograms included information on clinical T stage, presence of hydronephrosis, whether a visibly complete transurethral resection of bladder tumor was performed, age, sex, and tumor grade. The predictive accuracy of these nomograms was assessed. For complete response, the area under the receiving operating characteristic curve was 0.69. The Harrell concordance index was 0.61 for both DSS and BI-DFS. Conclusions: Our nomograms allow individualized estimates of complete response, DSS, and BI-DFS. They may assist patients and clinicians making important treatment decisions.

  10. "A force illegible": A study of Emily Dickinson's view of God 

    E-Print Network [OSTI]

    Thompson, Margaret Henderson

    1970-01-01

    , on nature, death and immortality, he shows something of her religious 2Ann Arbor, 1957. Originally published in New York in 1938. Cambridge, Massachusetts, 1955. views, but this is not his main empha is. The la chapter, "The Colossal Substance... partner to the Creator, although he is iotally dependent on God. His interpretation is that, for Emily, God is not yet perfected and may never be According to this view, when God achieves fulf illmeni it wi'1 be partially due to man's efforts, too...

  11. Experiments at Scale with In-Situ Visualization Using ParaView/Catalyst in RAGE

    SciTech Connect (OSTI)

    Kares, Robert John

    2014-10-31

    In this paper I describe some numerical experiments performed using the ParaView/Catalyst in-situ visualization infrastructure deployed in the Los Alamos RAGE radiation-hydrodynamics code to produce images from a running large scale 3D ICF simulation on the Cielo supercomputer at Los Alamos. The detailed procedures for the creation of the visualizations using ParaView/Catalyst are discussed and several images sequences from the ICF simulation problem produced with the in-situ method are presented. My impressions and conclusions concerning the use of the in-situ visualization method in RAGE are discussed.

  12. Under-Sodium Viewing: A Review of Ultrasonic Imaging Technology for Liquid Metal Fast Reactors

    SciTech Connect (OSTI)

    Griffin, Jeffrey W.; Peters, Timothy J.; Posakony, Gerald J.; Chien, Hual-Te; Bond, Leonard J.; Denslow, Kayte M.; Sheen, Shuh-Haw; Raptis, Paul

    2009-03-27

    This current report is a summary of information obtained in the "Information Capture" task of the U.S. DOE-funded "Under Sodium Viewing (USV) Project." The goal of the multi-year USV project is to design, build, and demonstrate a state-of-the-art prototype ultrasonic viewing system tailored for periodic reactor core in-service monitoring and maintenance inspections. The study seeks to optimize system parameters, improve performance, and re-establish this key technology area which will be required to support any new U.S. liquid-metal cooled fast reactors.

  13. Television Viewing, Walking Speed and Grip Strength in a Prospective Cohort Study

    E-Print Network [OSTI]

    Keevil, Victoria L.; Wijndaele, Katrien; Luben, Robert; Sayer, Avan A.; Wareham, Nicholas J.; Khaw, Kay-Tee

    2014-07-18

    , strong and consistent associations between grip strength and TV viewing time were not observed. Isometric muscle strength encapsulates only one aspect of muscle func- tion, and low performance may be present without low strength or vice versa, a concept... for age, physical activity, anthropome- try, wealth, comorbidity, smoking, and alcohol intake and combined if no sex–TV viewing time interactions were identified. Results: Men and women who watched the least TV at the 2HC or 3HC walked at a faster usual...

  14. Electron string ion sources for carbon ion cancer therapy accelerators

    E-Print Network [OSTI]

    Boytsov, A Yu; Donets, E D; Donets, E E; Katagiri, K; Noda, K; Ponkin, D O; Ramzdorf, A Yu; Salnikov, V V; Shutov, V B

    2015-01-01

    The Electron String type of Ion Sources (ESIS) was developed, constructed and tested first in the Joint Institute for Nuclear Research. These ion sources can be the appropriate sources for production of pulsed C4+ and C6+ ion beams which can be used for cancer therapy accelerators. In fact the test ESIS Krion-6T already now at the solenoid magnetic field only 4.6 T provides more than 10^10 C4+ ions per pulse and about 5*10^9 C6+ ions per pulse. Such ion sources could be suitable for application at synchrotrons. It was also found, that Krion-6T can provide more than 10^11 C6+ ions per second at 100 Hz repetition rate, and the repetition rate can be increased at the same or larger ion output per second. This makes ESIS applicable at cyclotrons as well. As for production of 11C radioactive ion beams ESIS can be the most economic kind of ion source. To proof that the special cryogenic cell for pulse injection of gaseous species into electron string was successfully tested using the ESIS Krion-2M.

  15. Osteogenic Sarcoma of the Maxilla: Neutron Therapy for Unresectable Disease

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Smoron, Geoffrey L.; Lennox, Arlene J.; Mcgee, James L.

    1999-01-01

    Purpose. To present a case study involving the use of fast neutron therapy to treat an extensive unresectable osteogenic sarcoma arising from the left maxilla. Patient. A 14-year-old male presented with a massive tumor producing severe distortion of his facial structures. He had already received six courses of chemotherapy, which had reduced his pain, but had not measurably reduced the tumor. Methods. The patient was treated with 66 MeV fast neutrons to a dose of 20.4 Gy in 13 fractions over 35 days. Results. CT assessments indicate gradually increasing calcification and noticeable reductionmore »of soft-tissue disease in the frontal sinus, orbit and maxillary antrum.There has been some recontouring of the facial structures.The boy conducts an active life, has no pain, and feels well. He was 17 years old at the last follow-up. Discussion. Fast neutrons have a greater biological effectiveness than conventional photon beams. Their use has been associated with improved chance for local control of unresectable disease.This case illustrates their effectiveness in controlling an unusual and aggressive osteogenic sarcoma of the facial bone and sinuses. « less

  16. Radiant{trademark} Liquid Radioisotope Intravascular Radiation Therapy System

    SciTech Connect (OSTI)

    Eigler, N.; Whiting, J.; Chernomorsky, A.; Jackson, J.; Knapp, F.F., Jr.; Litvack, F.

    1998-01-16

    RADIANT{trademark} is manufactured by United States Surgical Corporation, Vascular Therapies Division, (formerly Progressive Angioplasty Systems). The system comprises a liquid {beta}-radiation source, a shielded isolation/transfer device (ISAT), modified over-the-wire or rapid exchange delivery balloons, and accessory kits. The liquid {beta}-source is Rhenium-188 in the form of sodium perrhenate (NaReO{sub 4}), Rhenium-188 is primarily a {beta}-emitter with a physical half-life of 17.0 hours. The maximum energy of the {beta}-particles is 2.1 MeV. The source is produced daily in the nuclear pharmacy hot lab by eluting a Tungsten-188/Rhenium-188 generator manufactured by Oak Ridge National Laboratory (ORNL). Using anion exchange columns and Millipore filters the effluent is concentrated to approximately 100 mCi/ml, calibrated, and loaded into the (ISAT) which is subsequently transported to the cardiac catheterization laboratory. The delivery catheters are modified Champion{trademark} over-the-wire, and TNT{trademark} rapid exchange stent delivery balloons. These balloons have thickened polyethylene walls to augment puncture resistance; dual radio-opaque markers and specially configured connectors.

  17. FusionArc optimization: A hybrid volumetric modulated arc therapy (VMAT) and intensity modulated radiation therapy (IMRT) planning strategy

    SciTech Connect (OSTI)

    Matuszak, Martha M.; McShan, Daniel L.; Ten Haken, Randall K. [Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan 48109 (United States); Steers, Jennifer M. [Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan 48109 and Department of Nuclear Engineering and Radiological Sciences, University of Michigan, Ann Arbor, Michigan 48109 (United States); Long, Troy; Edwin Romeijn, H. [Department of Industrial and Operations Engineering, University of Michigan, Ann Arbor, Michigan 48109 (United States); Fraass, Benedick A. [Department of Radiation Oncology, Cedars-Sinai Medical Center, Los Angeles, California 90048 (United States)

    2013-07-15

    Purpose: To introduce a hybrid volumetric modulated arc therapy/intensity modulated radiation therapy (VMAT/IMRT) optimization strategy called FusionArc that combines the delivery efficiency of single-arc VMAT with the potentially desirable intensity modulation possible with IMRT.Methods: A beamlet-based inverse planning system was enhanced to combine the advantages of VMAT and IMRT into one comprehensive technique. In the hybrid strategy, baseline single-arc VMAT plans are optimized and then the current cost function gradients with respect to the beamlets are used to define a metric for predicting which beam angles would benefit from further intensity modulation. Beams with the highest metric values (called the gradient factor) are converted from VMAT apertures to IMRT fluence, and the optimization proceeds with the mixed variable set until convergence or until additional beams are selected for conversion. One phantom and two clinical cases were used to validate the gradient factor and characterize the FusionArc strategy. Comparisons were made between standard IMRT, single-arc VMAT, and FusionArc plans with one to five IMRT/hybrid beams.Results: The gradient factor was found to be highly predictive of the VMAT angles that would benefit plan quality the most from beam modulation. Over the three cases studied, a FusionArc plan with three converted beams achieved superior dosimetric quality with reductions in final cost ranging from 26.4% to 48.1% compared to single-arc VMAT. Additionally, the three beam FusionArc plans required 22.4%-43.7% fewer MU/Gy than a seven beam IMRT plan. While the FusionArc plans with five converted beams offer larger reductions in final cost-32.9%-55.2% compared to single-arc VMAT-the decrease in MU/Gy compared to IMRT was noticeably smaller at 12.2%-18.5%, when compared to IMRT.Conclusions: A hybrid VMAT/IMRT strategy was implemented to find a high quality compromise between gantry-angle and intensity-based degrees of freedom. This optimization method will allow patients to be simultaneously planned for dosimetric quality and delivery efficiency without switching between delivery techniques. Example phantom and clinical cases suggest that the conversion of only three VMAT segments to modulated beams may result in a good combination of quality and efficiency.

  18. Liposome-anchored local delivery of immunomodulatory agents for tumor therapy

    E-Print Network [OSTI]

    Kwong, Brandon (Brandon Wai-Sing)

    2012-01-01

    Immunostimulatory therapies that activate immune response pathways are of great interest for overcoming the immunosuppression present in advanced tumors. Agonistic antibodies against the co-stimulatory receptors CD40 and ...

  19. Home ultraviolet light therapy for psoriasis: Why patients choose other options

    E-Print Network [OSTI]

    Dothard, Emily H.; Sandoval, Laura F.; Yentzer, Brad A.; Feldman, Steven R.

    2015-01-01

    of psoriasis [5]. A home light unit may therefore be theyou/your child for a home UV light device. I just need aboutFebruary 2015 Commentary Home ultraviolet light therapy for

  20. Relative Merits of X-ray, Proton and Carbon Beam Therapy | ornl...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Relative Merits of X-ray, Proton and Carbon Beam Therapy Apr 09 2014 03:00 PM - 04:00 PM Prof. Oliver Jkel, University of Heidelberg, Heidelberg, Germany ORNL, Physics Division...

  1. OUTCOMES OF ANTHROPOLOGICALLY BASED CULTURAL COMPETENCY EDUCATION FOR DOCTORAL STUDENTS IN PHYSICAL THERAPY

    E-Print Network [OSTI]

    Drassen Ham, Amy

    2013-08-31

    understand the usefulness of cultural competency education for students in physical therapy. This research examines (1) how participants used cultural competency education at the point of clinical engagement, (2) if increased amount of education translates...

  2. Moral obligation and the human germ-line gene therapy debate 

    E-Print Network [OSTI]

    Clark, Alan B

    1998-01-01

    genetic engineering, there are few arguments made for a positive moral obligation to genetic intervention. This is especially so with respect to human germ-line gene therapy. Burke. K. Zimmerman makes one of the few arguments that society...

  3. A microfluidic platform for combinatorial synthesis and optimization of targeted polymeric nanoparticles for cancer therapy

    E-Print Network [OSTI]

    Valencia, Pedro M. (Pedro Miguel)

    2013-01-01

    The use of nanotechnology to engineer drug delivery vehicles comprised of controlled release polymers with targeting molecules has the potential to revolutionize cancer therapy, among other diseases. Although a myriad of ...

  4. The effectiveness of cognitive processing therapy and prolonged exposure in the Department of Veterans Affairs.

    E-Print Network [OSTI]

    Rutt, Benjamin T.

    2015-08-31

    Multiple randomized clinical trials have shown that cognitive processing therapy (CPT) and prolonged exposure (PE) are evidence-based treatments for posttraumatic stress disorder (PTSD). However, additional research should ...

  5. High-throughput approaches to sourcing of human hepatocytes for cell-based therapies

    E-Print Network [OSTI]

    Shan, Jing (Jing Meghan)

    2014-01-01

    Chronic liver disease affects more than 500 million people worldwide. The only therapy shown to directly prevent mortality is organ transplantation. However, there is growing discrepancy between supply and demand of ...

  6. A novel means of cardiac catheter guidance for ablation therapy of ventricular tachycardia

    E-Print Network [OSTI]

    Lv, Wener

    2014-01-01

    This work presents a system for identifying the site of origin of ventricular tachycardia (VT) and guiding a catheter to that site in order to deliver radio-frequency (RF) ablation therapy. Myocardial infarction (MI), also ...

  7. Overcoming cancer therapy resistance by targeting inhibitors of apoptosis proteins and nuclear factor-kappa B

    E-Print Network [OSTI]

    Dai, Yao; Lawrence, Theodore S.; Xu, Liang

    2008-10-25

    Chemo- or radioresistance markedly impairs the efficacy of cancer therapy and involves anti-apoptotic signal transduction pathways that prevent cell death. In resistant cancer cells, both inhibitors of apoptosis proteins ...

  8. Radiobiological evaluation of new boron delivery agents for boron neutron capture therapy

    E-Print Network [OSTI]

    Chung, Yoonsun

    2008-01-01

    This thesis evaluates the radiobiological effectiveness of three new boron compounds namely a boronated porphyrin (BOPP) and two liposome formulations for neutron capture therapy (BNCT). The methodology utilizes in vitro ...

  9. The investigation of controlled release microchips, nanoparticles, and sirna for gene therapy in tissue engineering applications 

    E-Print Network [OSTI]

    Chern, Christina

    2009-05-15

    The study of drug delivery for the treatment of illnesses and injuries is an important area of pharmaceutical technology. A relatively new area of drug delivery being explored is gene therapy, which utilizes the idea that genes can be used...

  10. The impact of poetry therapy on symptoms of secondary posttraumatic stress disorder in domestic violence counselors 

    E-Print Network [OSTI]

    Boone, Beth Carol

    2009-05-15

    This study examines the effectiveness of internet-based poetry therapy on symptoms of secondary posttraumatic stress disorder (SPTSD) in domestic violence counselors, and explores correlations between demographic, workplace and personality variables...

  11. View-based dynamic object recognition based on human perception Heinrich H. Bulthoff, Christian Wallraven, Arnulf Graf

    E-Print Network [OSTI]

    of a particular object or ob- ject category. For example, frontal-, side- or top-views of a helicopter are very

  12. Bunker View: Limited-range head-motion-parallax visualization for complex data sets

    E-Print Network [OSTI]

    Pollefeys, Marc

    of head-motion-parallax. In particular, the frame rates are often too low for convincing headBunker View: Limited-range head-motion-parallax visualization for complex data sets Andrei State Chapel Hill, North Carolina, 27514 ABSTRACT This work presents a head-motion-parallax visualization

  13. Reduced form electricity spot price modeling with a view towards spike risk

    E-Print Network [OSTI]

    Gerkmann, Ralf

    Reduced form electricity spot price modeling with a view towards spike risk Prof. Dr. Meyer. Februar 2010, 16:15 Uhr Seminarraum, Ludwigstraße 33 I The recent deregulation of electricity markets has led to the creation of energy exchanges, where the electricity is freely traded. We study the most

  14. Machine Ethics and Human Ethics: A Critical View Francesco Amigoni and Viola Schiaffonati

    E-Print Network [OSTI]

    Amigoni, Francesco

    Machine Ethics and Human Ethics: A Critical View Francesco Amigoni and Viola Schiaffonati@elet.polimi.it Abstract The rapid changes in the relationship between humans and machines evidence a progressive delegation of some human activities to machines. Among those, there are not only physical activities but also

  15. New Hampshire Resident Views on the Use, Availability, and Need for Public Transportation

    E-Print Network [OSTI]

    New Hampshire, University of

    New Hampshire Resident Views on the Use, Availability, and Need for Public Transportation Full project of the University of New Hampshire's Institute on Disability/UCED and the Community Action Program Belknap-Merrimack Counties, Inc. to document New Hampshire residents' perceptions about their access

  16. Maotai 3.0: Automatic Detection of View Access in VOPP K. Leung and Z. Huang

    E-Print Network [OSTI]

    Huang, Zhiyi

    ) model. VOPP is a shared-memory-based, data-centric model that uses "views" to bundle mutual exclusion is designed to eliminate data race [4, 5]. VOPP is a data-centric model, where shared data objects other data-centric models [8], VOPP bundles mutual exclusion and data access together and therefore

  17. SUPERVISED AND UNSUPERVISED MRF BASED 3D SCENE CLASSIFICATION IN MULTIPLE VIEW

    E-Print Network [OSTI]

    SUPERVISED AND UNSUPERVISED MRF BASED 3D SCENE CLASSIFICATION IN MULTIPLE VIEW AIRBORNE OBLIQUE Classification in 3D object space Basic idea Supervised approach Unsupervised approah Experiments: data and results Discussion CONTENTS #12; State-of-the-Art digital camera hardware and processing stimuate

  18. Reflective responsibility for risk: a critical view of software and information systems development risk

    E-Print Network [OSTI]

    De Montfort University

    evaluation of future states because the future is by definition unknown. Risks as known uncertaintiesReflective responsibility for risk: a critical view of software and information systems development risk management Bernd Carsten Stahl Faculty of Computer Science and Engineering, Centre for Computing

  19. Linking ArcView 3.0TM and XGobi: Insight Behind the Front End

    E-Print Network [OSTI]

    Symanzik, Jürgen

    of the implementation of a bidirectional link between the Geographic Information System GIS ArcView 3.0TM; Geographic information system; Imple- mentation issues; Spatial cumulative distribution function; Spatial statistics; Spatially lagged scatterplot; Variogram cloud plot. 1 Introduction Geographic Information Systems

  20. Linking ArcView 3.0TM and XGobi: Insight Behind the Front End

    E-Print Network [OSTI]

    Symanzik, Jürgen

    of a bidirectional link between the Geographic Information System (GIS) ArcView 3.0TM and the interactive dynamic Information Systems (GISs) are used extensively for examining spa- tial data but, traditionally, they have few tools necessary for displaying geographic information. The lack of ex- ploratory tools in a GIS

  1. Cross-sectional Views of 90/90 Pipe Without/With a Weld

    E-Print Network [OSTI]

    McDonald, Kirk

    Cross-sectional Views of 90/90 Pipe Without/With a Weld Yan 9-20-2012 #12;Outlines · Define the Locations of the Profiles · Pipe without A Weld (#Grid = 0.8×106) ­ Display in Tecplot: Figs.(a) ­ Display in FLUENT: Figs.(b) · Contours of Turbulence Intensity in Tecplot ­ Pipe with A Weld (#Grid = 1

  2. Diurnal temperature range over the United States: A satellite view Donglian Sun,1

    E-Print Network [OSTI]

    Sun, Donglian

    Diurnal temperature range over the United States: A satellite view Donglian Sun,1 Rachel T. Pinker; published 4 March 2006. [1] Diurnal temperature range (DTR) is an important climate change index. Information on this parameter comes primarily from sparse and unevenly distributed observations of shelter air

  3. God and the Human Experience A physicist's case for a theistic world view

    E-Print Network [OSTI]

    Gea-Banacloche, Julio

    God and the Human Experience A physicist's case for a theistic world view Julio Gea-Banacloche 1, starting from the basic facts about the human experience of existence. For convenience (but also, when they, in turn, experience the need to look beyond the simple conception of God that saw them

  4. God and the human experience A physicist's case for a theistic world view

    E-Print Network [OSTI]

    Gea-Banacloche, Julio

    God and the human experience A physicist's case for a theistic world view Julio Gea-Banacloche 1 and--possibly--relate to that reality, by considering the various aspects of our (human beings') experience of existence. For convenience (but also with an ulterior theological purpose in mind

  5. VISSOFT'07 Submission Kagdi, Maletic Onion Graphs for Focus+Context Views of UML Class Diagrams

    E-Print Network [OSTI]

    Maletic, Jonathan I.

    VISSOFT'07 Submission Kagdi, Maletic Onion Graphs for Focus+Context Views of UML Class Diagrams+context technique for visualizing large UML class models. The focus area, which can be manually or automatically source project. 1. Introduction Developers find UML class models1 useful for designing systems along

  6. A molecular thermodynamic view of DNAdrug interactions: a case study of 25 minor-groove binders

    E-Print Network [OSTI]

    Jayaram, Bhyravabotla

    A molecular thermodynamic view of DNA­drug interactions: a case study of 25 minor-groove binders-groove recognition by small molecules via a computational study on 25 DNA­drug complexes. The studies are configured of this study. While highlighting the favorable role of packing, shape complementarity, and van der Waals

  7. CLAS12 Software Workshop Broad view of the state-of-the-art in

    E-Print Network [OSTI]

    Gilfoyle, Jerry

    CLAS12 Software Workshop Goals: Broad view of the state-of-the-art in offline analysis. Status of the CLAS12 software program. Opportunities for users to join that program. Tutorials on CLAS12 software://conferences.jlab.org/CLAS12Software/index.html CLAS12 Software Workshop ­ p. 1/ #12;CLAS12 Software Workshop Program (Morning

  8. View Based Integration of Heterogeneous Web Service Registries--the Case of VISR

    E-Print Network [OSTI]

    Dustdar, Schahram

    View Based Integration of Heterogeneous Web Service Registries--the Case of VISR Schahram Dustdar efforts in the Web service area, several dif- ferent incompatible Web service registry implementations distributed Web service registries. In addition, the creation of specialized Web service registries leads

  9. Critical issues and current views on teaching basic circuits and systems in electrical engineering education

    E-Print Network [OSTI]

    education Joos Vandewalle Department of Electrical Engineering (ESAT) Katholieke Universiteit Leuven B-3001, its impact in the electrical engineering education and in order to increase the intrinsic interestCritical issues and current views on teaching basic circuits and systems in electrical engineering

  10. NEWS & VIEWS nature physics | VOL 2 | JUNE 2006 | www.nature.com/naturephysics 367

    E-Print Network [OSTI]

    Loss, Daniel

    solar cycle to be at its weakest in almost a century. A recent prediction to the contrary could turnNEWS & VIEWS nature physics | VOL 2 | JUNE 2006 | www.nature.com/naturephysics 367 SOLAR PHYSICS Back to the next solar cycle Many solar physicists expect the peak sunspot activity during the next

  11. Managing United States Public Lands in Response to Climate Change: A View From the Ground Up

    E-Print Network [OSTI]

    Neff, Jason

    Managing United States Public Lands in Response to Climate Change: A View From the Ground Up and resource managers, it is not yet clear how issues related to climate change will be incorporated into on in which climate change or carbon management may intersect other use goals: forests, biofuels, and grazing

  12. TrafficView: Traffic Data Dissemination using Car-to-Car Communication

    E-Print Network [OSTI]

    Iftode, Liviu

    TrafficView: Traffic Data Dissemination using Car-to-Car Communication Tamer Nadeema, Sasan high- tech devices are integrated, and a common platform for inter-vehicle communication is necessary platform for inter-vehicle communication is necessary to realize an intelligent transportation system

  13. 142 NATURE GEOSCIENCE | VOL 4 | MARCH 2011 | www.nature.com/naturegeoscience news & views

    E-Print Network [OSTI]

    that nature took care of the spill, at least as far as gas is concerned. Nevertheless, the studies should humans do -- be it oil spills or greenhouse gas emissions -- the environmental and economic costs142 NATURE GEOSCIENCE | VOL 4 | MARCH 2011 | www.nature.com/naturegeoscience news & views much

  14. View from the Cloud Editor: George Pallis gpallis@cs.ucy.ac.cy

    E-Print Network [OSTI]

    's susceptible to security threats. Security concerns also arise because public clouds are designed under cloud would deliver some of the same long-recognized security benefits as has open source softwareView from the Cloud Editor: George Pallis · gpallis@cs.ucy.ac.cy 2 Published by the IEEE Computer

  15. IEEE 1451 standard and wireless sensor networks: An over view of fault tolerant algorithms

    E-Print Network [OSTI]

    227 IEEE 1451 standard and wireless sensor networks: An over view of fault tolerant algorithms Shubha Kher Senior member IEEE, Jinran Chen and Arun K Somani, Fellow IEEE Dependable Computing Lab, Iowa state University, Ames, IA 50011 tshubhajrchen,arun @,iastate. edu Abstract The IEEE 1451 standards

  16. Co-sponsored by ME and CEMS Departments The Outlook for Energy: A View

    E-Print Network [OSTI]

    Fisher, Frank

    ) Darnell Manager, Research and Development Support Services ExxonMobil Research & Engineering Company ABSTRACT The Outlook for Energy is ExxonMobil's long-term view of our shared energy future. We developed to help guide our own strategies and investments. Over the next five years, ExxonMobil expects to invest

  17. Co-sponsored by CEMS and ME Departments The Outlook for Energy: A View

    E-Print Network [OSTI]

    Fisher, Frank

    Section Head, Emerging Energy Science Corporate Strategic Research ExxonMobil Research & Engineering Company ABSTRACT The Outlook for Energy is ExxonMobil's long-term view of our shared energy future. We to help guide our own strategies and investments. Over the next five years, ExxonMobil expects to invest

  18. Co-sponsored by CEMS and ME Departments The Outlook for Energy: A View

    E-Print Network [OSTI]

    Fisher, Frank

    ) Darnell Manager, Research and Development Support Services ExxonMobil Research & Engineering Company ABSTRACT The Outlook for Energy is ExxonMobil's long-term view of our shared energy future. We develop to help guide our own strategies and investments. Over the next five years, ExxonMobil expects to invest

  19. 98 NATURE CLIMATE CHANGE | VOL 1 | MAY 2011 | www.nature.com/natureclimatechange news & views

    E-Print Network [OSTI]

    Lockwood, Mike

    98 NATURE CLIMATE CHANGE | VOL 1 | MAY 2011 | www.nature.com/natureclimatechange news & views that changes in solar output must be responsible for large changes in climate. This thinking neglects a key the effect that centennial-scale changes in solar activity have on climate4 . Initially, our best estimates

  20. Early View (EV): 1-EV Nice weather for bettongs: using weather events, not climate

    E-Print Network [OSTI]

    Turner, Monica G.

    distribution using temporally matched observations of the species with weather data (includ- ing extremeEarly View (EV): 1-EV Nice weather for bettongs: using weather events, not climate means applications of species distribution models (SDM) are typically static, in that they are based on correlations

  1. Network Utilization: the Flow View Avinatan Hassidim, Danny Raz, Michal Segalov Ariel Shaqed

    E-Print Network [OSTI]

    Cortes, Corinna

    Network Utilization: the Flow View Avinatan Hassidim, Danny Raz, Michal Segalov Ariel Shaqed Google a substantial investment. Therefore, there is an economical drive to increase the utilization of network, the utilization of network components has a direct impact on the performance of the network and its resilience

  2. View Operations on Objects with Roles for a Statically Typed Database Language

    E-Print Network [OSTI]

    Ghelli, Giorgio

    to the evolution of application requirements. It is widely recognized that long lasting, evolving databases need; |views mechanisms to adapt the database schema to the changing needs of users; |schema evolution,tosupport the rst twoaspects of database evolution: Author's address: Dipartimento di Informatica, Universit#12;a di

  3. Multiple Exciton Coherence Sizes in Photosynthetic Antenna Complexes viewed by Pump-Probe Spectroscopy

    E-Print Network [OSTI]

    Mukamel, Shaul

    Multiple Exciton Coherence Sizes in Photosynthetic Antenna Complexes viewed by Pump, 1996X The pump-probe signal from the light-harvesting antenna LH2 of purple bacteria is analyzed using absorption,4,5 pump-probe,11-16 and three pulse echoes.8,17 These measurements show ultrafast energy transfer

  4. VIEWS ON U.S. WATER RESEARCH AND TECHNOLOGY TRANSFER PROGRAMS

    E-Print Network [OSTI]

    District of Columbia, University of the

    #12;VIEWS ON U.S. WATER RESEARCH AND TECHNOLOGY TRANSFER PROGRAMS By MAMADOU H. WATT, Director . . . . . . . . . . 18 5. Technology Transfer and Information Dissemination . . . . 20 5.1 Definition and Purpose. . . . . . . . . . . . . . . 20 5.2 The Process of Technology Transfer. . . . . . . . . 21 5.3 Products of Technology Transfer

  5. NEWS & VIEWS nature physics | VOL 2 | JULY 2006 | www.nature.com/naturephysics 445

    E-Print Network [OSTI]

    Loss, Daniel

    . In tokamak-based fusion plasmas, reconnection occurs as a result of plasma instabilities and hampers magnetic confinement. It influences the dayside dynamics of the Earth's magnetosphere and the magnetic substormsNEWS & VIEWS nature physics | VOL 2 | JULY 2006 | www.nature.com/naturephysics 445 MAGNETIC

  6. Pathways for protein folding: is a "new view" needed? Vijay S Pande1

    E-Print Network [OSTI]

    Croquette, Vincent

    Pathways for protein folding: is a "new view" needed? Vijay S Pande1 , Alexander Yu Grosberg2 energy MG Molten globule Introduction How do proteins fold? While the thirty five years since Anfinsen has demonstrated the complexity of protein folding, the search continues for the general principles

  7. A Bayesian view on motor control and planning Marc Toussaint and Christian Goerick

    E-Print Network [OSTI]

    Toussaint, Marc

    A Bayesian view on motor control and planning Marc Toussaint and Christian Goerick Abstract. iterative Linear Quadratic Gaussian (iLQG)). Marc Toussaint Technical University Berlin, Franklinstr. 28-Legien-Strasse 30, 63073 Offenbach/Main, Germany, e- mail: christian.goerick@honda-ri.de 1 #12;2 Marc Toussaint

  8. Users' View on Context-Sensitive Car Advertisements Florian Alt, Christoph Evers, Albrecht Schmidt

    E-Print Network [OSTI]

    Users' View on Context-Sensitive Car Advertisements Florian Alt, Christoph Evers, Albrecht Schmidt.alt, albrecht.schmidt}@uni-due.de christoph.evers@stud.uni-due.de Abstract. Cars are ubiquitous and offer large static, with the exception of car-mounted displays that offer dy- namic content. With new display

  9. Sustained and Transient Modulation of Performance Induced by Emotional Picture Viewing

    E-Print Network [OSTI]

    Pessoa, Luiz

    Sustained and Transient Modulation of Performance Induced by Emotional Picture Viewing Mirtes-irrelevant emotional pictures affects the performance of a subsequent nonemotional visual detection task. Subjects performed target-detection trials following the offset of individual unpleasant, pleasant, and neutral

  10. April 22, 2010 Coronal hole boundaries evolution at small scales: II. XRT view

    E-Print Network [OSTI]

    April 22, 2010 Coronal hole boundaries evolution at small scales: II. XRT view Can small-scale outflows at CHBs be a source of the slow solar wind? S. Subramanian, M. S. Madjarska and J. G. Doyle Armagh to further explore the small-scale evolution of coronal hole boundaries using X-ray high-resolution and high

  11. University of Arkansas Libraries Prepare your Computer to View the New Crystal Reports

    E-Print Network [OSTI]

    Capogna, Luca

    University of Arkansas Libraries Prepare your Computer to View the New Crystal Reports 1. Go to My windows. 27. Now you should create a folder for your report(s) wherever is convenient for you (for example, folder. Name the new folder "My Reports" or "My Web Reports"--again, whatever is convenient. 28. In your

  12. News and Views Conference Report: Paleoanthropology of the Mani Peninsula (Greece)

    E-Print Network [OSTI]

    Delson, Eric

    News and Views Conference Report: Paleoanthropology of the Mani Peninsula (Greece) K. Harvati & E in Athens and Areopolis, Greece, on the Paleoanthropol- ogy of the Mani Peninsula. The conference publication outside Greece is a short article on forensic implications of damage to one cranium (Coutselinis

  13. DOE Zero Energy Ready Home Case Study: Clifton View Homes, Coupeville, Washington

    SciTech Connect (OSTI)

    none,

    2013-09-01

    Ted Clifton, founder of Clifton View Homes, achieved an impressive Home Energy Rating System (HERS) score of 34 (without solar panels) on a two-story home completed in July 2011 that also earned him his first Challenge Home certification from the U.S. Department of Energy (DOE). This home also garnered a 2013 Housing Innovation Award in the "systems builder" category.

  14. The Arab States and the Refugee Issue: A Retrospective View Jalal Al Husseini

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    The Arab States and the Refugee Issue: A Retrospective View Jalal Al Husseini I. Introduction This chapter aims at defining the Arab states' position with regard to the Palestinian refugee question and the legal status of the refugees in each of these states.2 However, little attention has been paid

  15. Internet use and non-use: views of older users ANNE MORRIS*, JOY GOODMAN

    E-Print Network [OSTI]

    Goodman, Joy

    1 Internet use and non-use: views of older users ANNE MORRIS*, JOY GOODMAN + AND HELENA BRADING: older people elderly Internet digital divide technology Abstract: This paper reports the results of two connected surveys of computer and Internet use among the older population in the UK. 120 questionnaires

  16. 184 NATURE CLIMATE CHANGE | VOL 3 | MARCH 2013 | www.nature.com/natureclimatechange news & views

    E-Print Network [OSTI]

    Thomas, David D.

    184 NATURE CLIMATE CHANGE | VOL 3 | MARCH 2013 | www.nature.com/natureclimatechange news & views better job of considering the full range of biodiversity in natural populations of marine species than we@usc.edu References 1. Schaum, E., Rost, B., Millar, A. J. & Collins, S. Nature Clim. Change 3, 298­302 (2013). 2

  17. NATURE CLIMATE CHANGE | VOL 1 | APRIL 2011 | www.nature.com/natureclimatechange 29 news & views

    E-Print Network [OSTI]

    Polvani, Lorenzo M.

    NATURE CLIMATE CHANGE | VOL 1 | APRIL 2011 | www.nature.com/natureclimatechange 29 news & views of experiments in which they added inorganic forms of nitrogen, amino acids and peptides to soils and plants from acquires nitrogen in the field. Their results provide compelling evidence that the species is able to take

  18. Cauchy transforms of measures viewed as some functionals of Fourier transforms #

    E-Print Network [OSTI]

    Jurek, Zbigniew J.

    Cauchy transforms of measures viewed as some functionals of Fourier transforms # Zbigniew J. Jurek Urbanik ABSTRACT. The Cauchy transform of a positive measure plays an impor­ tant role in complex analysis and more recently in so­called free probability. We show here that the Cauchy transform restricted

  19. Cauchy transforms of measures viewed as some functionals of Fourier transforms

    E-Print Network [OSTI]

    Jurek, Zbigniew J.

    Cauchy transforms of measures viewed as some functionals of Fourier transforms Zbigniew J. Jurek Urbanik ABSTRACT. The Cauchy transform of a positive measure plays an impor- tant role in complex analysis and more recently in so-called free probability. We show here that the Cauchy transform restricted

  20. NATURE CHEMISTRY | VOL 3 | SEPTEMBER 2011 | www.nature.com/naturechemistry 659 news & views

    E-Print Network [OSTI]

    Sia, Samuel K.

    ion (uranium). The use of chemistry for improving sensors is particularly inspired. Current workNATURE CHEMISTRY | VOL 3 | SEPTEMBER 2011 | www.nature.com/naturechemistry 659 news & views D if analogous enzymes are available for the analyte of interest. Writing in Nature Chemistry, Yi Lu and Yu Xiang

  1. View Dependence of 3D Recovery from Folded Pictures and Warped 3D Faces

    E-Print Network [OSTI]

    Cavanagh, Patrick

    View Dependence of 3D Recovery from Folded Pictures and Warped 3D Faces Patrick Cavanagh Department vertical lines through the nose and the eyes. When this folded picture is tilted back and forth, the same is true, over a more restricted range of angles, as we move in front of a picture of an object

  2. Early View (EV): 1-EV Historical climate-change influences modularity and nestedness of

    E-Print Network [OSTI]

    Chittka, Lars

    , and then test these against empirical data. We propose that historical climate-change may have left imprintsEarly View (EV): 1-EV Historical climate-change influences modularity and nestedness of pollination. Wang, and C. Rahbek, Center for Macroecology, Evolution and Climate, Univ. of Copenhagen

  3. National Aeronautics and Space Administration GoddardViewVolume 5 Issue 8

    E-Print Network [OSTI]

    Christian, Eric

    ­ 9 Honey Bees Turned Data Collectors Help Scientists Understand Climate Change ­ 10 Goddard Family Discover will host NASA's climate simulations for the Intergovern- mental Panel on Climate Change. PhotoNational Aeronautics and Space Administration GoddardViewVolume 5 Issue 8 Climate Simulation

  4. nature methods | VOL.11 NO.2 | FEBRUARY 2014 | 117 Points of View

    E-Print Network [OSTI]

    Cai, Long

    encoding and preferred over the angle-based strategy used in pie charts (Fig. 1a). Often the counts that we bar chart is equivalent to multiple pie charts, yet a grouped bar chart affords more accurate readingsnature methods | VOL.11 NO.2 | FEBRUARY 2014 | 117 this month Points of View Bar charts and box

  5. nature physics | VOL 6 | DECEMBER 2010 | www.nature.com/naturephysics 939 news & views

    E-Print Network [OSTI]

    Loss, Daniel

    the transition from what we now call `classical' to `modern' physics. With the new concepts and fields of studynature physics | VOL 6 | DECEMBER 2010 | www.nature.com/naturephysics 939 news & views coherent). For physics, the first half of the twentieth century was a time of profound transformation, bringing about

  6. Materialized views for P2P XML warehousing Ioana Manolescu Spyros Zoupanos

    E-Print Network [OSTI]

    Manolescu, Ioana

    , the European defense company, and CEA, the French nuclear energy producer. The project focuses on giving in the number of views, and describe rewriting algorithms. Our approach is validated by experiments these companies efficient tools for gathering, enriching and exploiting (e.g. by semantic and linguistic analysis

  7. 798 | VOL.6 NO.11 | NOVember 2009 | nature methods news and views

    E-Print Network [OSTI]

    Cai, Long

    798 | VOL.6 NO.11 | NOVember 2009 | nature methods news and views approaches designed to identify. Ear, P.H. & Michnick, S.W. Nat. Methods 6, 813­ 816 (2009). 3. Dixon, S.J., Costanzo, M., Baryshnikova crystal structure. This approach has been extremely powerful and the two high- lighted studies1,2 expand

  8. A CSP View on UMLRT structure diagrams Clemens Fischer, ErnstRudiger Olderog and Heike Wehrheim

    E-Print Network [OSTI]

    Habel, Annegret

    A CSP View on UML­RT structure diagrams Clemens Fischer, Ernst­R¨udiger Olderog and Heike Wehrheim UML­RT structure diagrams together with the formal method CSP­OZ combining CSP and Object­Z. While CSP­OZ is used for specifying the system components themselves (by CSP­OZ classes), UML­RT diagrams provide

  9. Learnability of Interactive Coordinated-View Visualizations Sujatha Krishnamoorthy, Christopher North

    E-Print Network [OSTI]

    features which are desirable for novice-friendliness: Task based organization of coordinated views charts and bar graphs and weather information on maps as seen in weather news broadcasts. · General website would be familiar with WIMP interfaces. An informal survey revealed that bar-charts and pie-charts

  10. INTRODUCTION The caudal fin of fishes has often been viewed by engineers as a

    E-Print Network [OSTI]

    Flammang, Brooke

    56 INTRODUCTION The caudal fin of fishes has often been viewed by engineers as a relatively simple propulsive surface that is flapped by fish in a two- dimensional motion that is an extension; Anton et al., 2009). However, in many fishes the caudal fin is used not exclusively for thrust

  11. Sleep Deprivation Impairs Object-Selective Attention: A View from the Ventral Visual Cortex

    E-Print Network [OSTI]

    Pennsylvania, University of

    attention task. During this task, pictures of houses or faces were randomly interleaved among scrambled images. Across different blocks, volunteers responded to house but not face pictures, face but not house pictures, or passively viewed pictures without responding. The appearance of task-relevant pictures

  12. Hierarchical Volumetric Multi-view Stereo Reconstruction of Manifold Surfaces based on Dual Graph Embedding

    E-Print Network [OSTI]

    Kazhdan, Michael

    Hierarchical Volumetric Multi-view Stereo Reconstruction of Manifold Surfaces based on Dual Graph://www.rwth-graphics.de Abstract This paper presents a new volumetric stereo algorithm to reconstruct the 3D shape of an arbitrary into the volumetric grid, which establishes a well defined relationship between the integrated photo

  13. New Dimensions of Visual Landscape Assessment Wildlands Management for Wildlife Viewing1

    E-Print Network [OSTI]

    Standiford, Richard B.

    preservation and other activities associated with traditional game management. Fortunately, much of the knowledge and techniques developed for game #12;management can be transferred to considerations of wildlifeNew Dimensions of Visual Landscape Assessment Wildlands Management for Wildlife Viewing1 Tamsie

  14. NATURE NANOTECHNOLOGY | VOL 9 | DECEMBER 2014 | www.nature.com/naturenanotechnology 965 news & views

    E-Print Network [OSTI]

    Aeschlimann, Martin

    for ever-smaller spintronic devices that are both energy efficient and non-volatile. One promising approach & views MOLECULAR SPINTRONICS Topology communicates A magnetic skyrmion lattice can mediate transport-sensitive scanning tunnelling microscopy: a technique in which the local magnetization of a sample is measured using

  15. ---Search Finance Home Yahoo! Help Welcome, dalemeade08540 [ ]Sign Out -My Yahoo! View Customize

    E-Print Network [OSTI]

    - - -Search Finance Home Yahoo! Help Welcome, dalemeade08540 [ ]Sign Out -My Yahoo! View Customize Financial News Enter symbol(s) Basic Get Symbol Lookup Associated Press EU Expected to Offer Japan Bigger, Russia, South Korea and China plan to join forces to research uses of fusion energy to create clean, long-term

  16. Spring 2014 View this email in your browser Hello from Berkeley Bioengineering!

    E-Print Network [OSTI]

    Alvarez-Cohen, Lisa

    Spring 2014 View this email in your browser Hello from Berkeley Bioengineering! It's been another program ranked 7th best in the U.S. New rankings from US News & World Report placed our bioengineeringth anniversary of the UC Berkeley - UCSF Graduate Program in Bioengineering, AIMBE Fellows Herr

  17. Decision Regret in Men Undergoing Dose-Escalated Radiation Therapy for Prostate Cancer

    SciTech Connect (OSTI)

    Steer, Anna N.; Aherne, Noel J.; Gorzynska, Karen; Hoffman, Matthew; Last, Andrew; Hill, Jacques; Shakespeare, Thomas P.; Rural Clinical School Faculty of Medicine, University of New South Wales, Coffs Harbour

    2013-07-15

    Purpose: Decision regret (DR) is a negative emotion associated with medical treatment decisions, and it is an important patient-centered outcome after therapy for localized prostate cancer. DR has been found to occur in up to 53% of patients treated for localized prostate cancer, and it may vary depending on treatment modality. DR after modern dose-escalated radiation therapy (DE-RT) has not been investigated previously, to our knowledge. Our primary aim was to evaluate DR in a cohort of patients treated with DE-RT. Methods and Materials: We surveyed 257 consecutive patients with localized prostate cancer who had previously received DE-RT, by means of a validated questionnaire. Results: There were 220 responses (85.6% response rate). Image-guided intensity modulated radiation therapy was given in 85.0% of patients and 3-dimensional conformal radiation therapy in 15.0%. Doses received included 73.8 Gy (34.5% patients), 74 Gy (53.6%), and 76 Gy (10.9%). Neoadjuvant androgen deprivation (AD) was given in 51.8% of patients and both neoadjuvant and adjuvant AD in 34.5%. The median follow-up time was 23 months (range, 12-67 months). In all, 3.8% of patients expressed DR for their choice of treatment. When asked whether they would choose DE-RT or AD again, only 0.5% probably or definitely would not choose DE-RT again, compared with 8.4% for AD (P<.01). Conclusion: Few patients treated with modern DE-RT express DR, with regret appearing to be lower than in previously published reports of patients treated with radical prostatectomy or older radiation therapy techniques. Patients experienced more regret with the AD component of treatment than with the radiation therapy component, with implications for informed consent. Further research should investigate regret associated with individual components of modern therapy, including AD, radiation therapy and surgery.

  18. Combined Ethanol Injection Therapy and Radiofrequency Ablation Therapy in Percutaneous Treatment of Hepatocellular Carcinoma Larger than 4 cm

    SciTech Connect (OSTI)

    Vallone, Paolo; Catalano, Orlando [National Cancer Institute, Department of Radiology (Italy)], E-mail: orlandcat@tin.it; Izzo, Francesco [National Cancer Institute, Department of Surgical Oncology 'D' (Italy); Siani, Alfredo [National Cancer Institute, Department of Radiology (Italy)

    2006-08-15

    Background. Optimal treatment of large-sized hepatocellular carcinoma (HCC) is still debated, because percutaneous ablation therapies alone do not always achieve complete necrosis. Objective. To report our experience in the treatment of patients with HCC larger than 4 cm in diameter by combined percutaneous ethanol injection and radiofrequency thermal ablation. Methods. In a 5-year period there were 40 consecutive patients meeting the inclusion criteria (24 men and 16 women; age range 41-72 years, mean 58 years). These subjects had a single HCC larger than 4 cm. Twelve subjects also had one or two additional nodules smaller than 4 cm (mean 1.2 nodules per patient). Patients were submitted to one to three sessions consisting of ethanol injection at two opposite tumor poles (mean 12 ml) and then of radiofrequency application through one or two electrodes placed at the tumor center (mean treatment duration 30 min). Results. Complete necrosis was obtained in all cases with one to three sessions (mean 1.3 sessions per patient). All patients experienced pain and fever but one only subject had a major complication requiring treatment (abscess development and fistulization). Overall follow-up was 7-69 months. Two patients showed local recurrence and 9 developed new etherotopic HCC nodules. Seven subjects died during follow-up while 33 were free from recurrence 8-69 months after treatment. Conclusion. A combination of ethanol injection and radiofrequency ablation is effective in the treatment of large HCC.

  19. Prairie View 

    E-Print Network [OSTI]

    Unknown

    2011-08-17

    . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 108 APPENDIX C . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 109 APPENDIX D . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 110 APPENDIX E...-pair. Here subscripts ij are omitted from piijQ, piijA and piijB. Prob. = Probability. . . . 46 III Interval estimates of ??Q by piA, piB,?A and ?B, for the flanking markers separated by ?AB = 20 cM under Haldane?s mapping function...

  20. Automatic CT simulation optimization for radiation therapy: A general strategy

    SciTech Connect (OSTI)

    Li, Hua, E-mail: huli@radonc.wustl.edu; Chen, Hsin-Chen; Tan, Jun; Gay, Hiram; Michalski, Jeff M.; Mutic, Sasa [Department of Radiation Oncology, Washington University, St. Louis, Missouri 63110 (United States)] [Department of Radiation Oncology, Washington University, St. Louis, Missouri 63110 (United States); Yu, Lifeng [Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905 (United States)] [Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905 (United States); Anastasio, Mark A. [Department of Biomedical Engineering, Washington University, St. Louis, Missouri 63110 (United States)] [Department of Biomedical Engineering, Washington University, St. Louis, Missouri 63110 (United States); Low, Daniel A. [Department of Radiation Oncology, University of California Los Angeles, Los Angeles, California 90095 (United States)] [Department of Radiation Oncology, University of California Los Angeles, Los Angeles, California 90095 (United States)

    2014-03-15

    Purpose: In radiation therapy, x-ray computed tomography (CT) simulation protocol specifications should be driven by the treatment planning requirements in lieu of duplicating diagnostic CT screening protocols. The purpose of this study was to develop a general strategy that allows for automatically, prospectively, and objectively determining the optimal patient-specific CT simulation protocols based on radiation-therapy goals, namely, maintenance of contouring quality and integrity while minimizing patient CT simulation dose. Methods: The authors proposed a general prediction strategy that provides automatic optimal CT simulation protocol selection as a function of patient size and treatment planning task. The optimal protocol is the one that delivers the minimum dose required to provide a CT simulation scan that yields accurate contours. Accurate treatment plans depend on accurate contours in order to conform the dose to actual tumor and normal organ positions. An image quality index, defined to characterize how simulation scan quality affects contour delineation, was developed and used to benchmark the contouring accuracy and treatment plan quality within the predication strategy. A clinical workflow was developed to select the optimal CT simulation protocols incorporating patient size, target delineation, and radiation dose efficiency. An experimental study using an anthropomorphic pelvis phantom with added-bolus layers was used to demonstrate how the proposed prediction strategy could be implemented and how the optimal CT simulation protocols could be selected for prostate cancer patients based on patient size and treatment planning task. Clinical IMRT prostate treatment plans for seven CT scans with varied image quality indices were separately optimized and compared to verify the trace of target and organ dosimetry coverage. Results: Based on the phantom study, the optimal image quality index for accurate manual prostate contouring was 4.4. The optimal tube potentials for patient sizes of 38, 43, 48, 53, and 58 cm were 120, 140, 140, 140, and 140 kVp, respectively, and the corresponding minimum CTDIvol for achieving the optimal image quality index 4.4 were 9.8, 32.2, 100.9, 241.4, and 274.1 mGy, respectively. For patients with lateral sizes of 43–58 cm, 120-kVp scan protocols yielded up to 165% greater radiation dose relative to 140-kVp protocols, and 140-kVp protocols always yielded a greater image quality index compared to the same dose-level 120-kVp protocols. The trace of target and organ dosimetry coverage and the ? passing rates of seven IMRT dose distribution pairs indicated the feasibility of the proposed image quality index for the predication strategy. Conclusions: A general strategy to predict the optimal CT simulation protocols in a flexible and quantitative way was developed that takes into account patient size, treatment planning task, and radiation dose. The experimental study indicated that the optimal CT simulation protocol and the corresponding radiation dose varied significantly for different patient sizes, contouring accuracy, and radiation treatment planning tasks.