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Note: This page contains sample records for the topic "integrated high throughput" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


1

Integrated crystal mounting and alignment system for high-throughput biological crystallography  

DOE Patents (OSTI)

A method and apparatus for the transportation, remote and unattended mounting, and visual alignment and monitoring of protein crystals for synchrotron generated x-ray diffraction analysis. The protein samples are maintained at liquid nitrogen temperatures at all times: during shipment, before mounting, mounting, alignment, data acquisition and following removal. The samples must additionally be stably aligned to within a few microns at a point in space. The ability to accurately perform these tasks remotely and automatically leads to a significant increase in sample throughput and reliability for high-volume protein characterization efforts. Since the protein samples are placed in a shipping-compatible layered stack of sample cassettes each holding many samples, a large number of samples can be shipped in a single cryogenic shipping container.

Nordmeyer, Robert A. (San Leandro, CA); Snell, Gyorgy P. (Richmond, CA); Cornell, Earl W. (Antioch, CA); Kolbe, William F. (Moraga, CA); Yegian, Derek T. (Oakland, CA); Earnest, Thomas N. (Berkeley, CA); Jaklevich, Joseph M. (Lafayette, CA); Cork, Carl W. (Walnut Creek, CA); Santarsiero, Bernard D. (Chicago, IL); Stevens, Raymond C. (La Jolla, CA)

2007-09-25T23:59:59.000Z

2

High throughput optical scanner  

DOE Patents (OSTI)

A scanning apparatus is provided to obtain automated, rapid and sensitive scanning of substrate fluorescence, optical density or phosphorescence. The scanner uses a constant path length optical train, which enables the combination of a moving beam for high speed scanning with phase-sensitive detection for noise reduction, comprising a light source, a scanning mirror to receive light from the light source and sweep it across a steering mirror, a steering mirror to receive light from the scanning mirror and reflect it to the substrate, whereby it is swept across the substrate along a scan arc, and a photodetector to receive emitted or scattered light from the substrate, wherein the optical path length from the light source to the photodetector is substantially constant throughout the sweep across the substrate. The optical train can further include a waveguide or mirror to collect emitted or scattered light from the substrate and direct it to the photodetector. For phase-sensitive detection the light source is intensity modulated and the detector is connected to phase-sensitive detection electronics. A scanner using a substrate translator is also provided. For two dimensional imaging the substrate is translated in one dimension while the scanning mirror scans the beam in a second dimension. For a high throughput scanner, stacks of substrates are loaded onto a conveyor belt from a tray feeder.

Basiji, David A. (Seattle, WA); van den Engh, Gerrit J. (Seattle, WA)

2001-01-01T23:59:59.000Z

3

High-Throughput Screening Techniques  

NLE Websites -- All DOE Office Websites (Extended Search)

Throughput Throughput Screening Techniques for Biomass Conversion Stephen R. Decker & Roman Brunecky & Melvin P. Tucker & Michael E. Himmel & Michael J. Selig Published online: 14 October 2009 # US Government 2009 Abstract High-throughput (HTP) screening of biomass or biomass-degrading enzymes, regardless of the desired outcome, is fraught with obstacles and challenges not typically faced in more traditional biotechnology. The enzyme systems are complex and synergistic and the substrate is highly heterogeneous, insoluble, and difficult to dispense. Digestions are often carried out for days at temperatures of 50°C or higher, leading to significant challenges regarding evaporation control in small well volumes. Furthermore, it is often desirable to condition or "pretreat" the biomass at extreme temperatures and/or pH to enhance enzyme digestibility.

4

High Throughput Single Molecule Investigation of Transcription  

E-Print Network (OSTI)

genomic DNA based on single-molecule detection. Analyticalmapping: a novel, single- molecule approach to genomic2011). High-throughput single-molecule optofluidic analysis.

Kim, Soohong

2012-01-01T23:59:59.000Z

5

Robust, High-Throughput Analysis of Protein Structures  

NLE Websites -- All DOE Office Websites (Extended Search)

Robust, High-Throughput Analysis of Protein Structures Print Robust, High-Throughput Analysis of Protein Structures Print Scientists have developed a fast and efficient way to determine the structure of proteins, shortening a process that often takes years into a matter of days. The Structurally Integrated BiologY for Life Sciences (SIBYLS) beamline at the ALS has implemented the world's highest-throughput biological-solution x-ray scattering beamline enabling genomic-scale protein-structure characterization. Coupling brilliant x rays from one of the superconducting bend magnets at the ALS to liquid-handling robotics has enabled the collection of 96 samples in 4 hours. Importantly, the sample format and the amount of material required are practical for most biological problems. The beamline's high-throughput capability is set to have a large impact on many fields that require genomic-scale information, such as Berkeley Lab's bioenergy efforts and cancer biology studies.

6

Graphene oxide-based micropatterns via high-throughput multiphoton-induced reduction and ablation  

Science Journals Connector (OSTI)

In this study, a developed temporal focusing-based femtosecond laser system provides high-throughput multiphoton-induced reduction and ablation of graphene oxide (GO) films. Integrated...

Li, Yi-Cheng; Yeh, Te-Fu; Huang, Hsin-Chieh; Chang, Hsin-Yu; Lin, Chun-Yu; Cheng, Li-Chung; Chang, Chia-Yuan; Teng, Hsisheng; Chen, Shean-Jen

2014-01-01T23:59:59.000Z

7

Potential of High-Throughput Experimentation with Ammonia Borane...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

Potential of High-Throughput Experimentation with Ammonia Borane Solid Hydrogen Storage Materials (presentation) Potential of High-Throughput Experimentation with Ammonia Borane...

8

High-Throughput and Combinatorial Screening of Hydrogen Storage...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

High-Throughput and Combinatorial Screening of Hydrogen Storage Materials (presentation) High-Throughput and Combinatorial Screening of Hydrogen Storage Materials (presentation)...

9

High-Throughput/Combinatorial Techniques in Hydrogen Storage...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

High-ThroughputCombinatorial Techniques in Hydrogen Storage Materials R&D (presentation) High-ThroughputCombinatorial Techniques in Hydrogen Storage Materials R&D (presentation)...

10

High Throughput/Combinatorial Screening of Hydrogen Storage Materials...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

UOP LLC. All rights reserved. High ThroughputCombinatorial Screening of Hydrogen Storage Materials: UOP Approaches High ThroughputCombinatorial Screening of Hydrogen Storage...

11

High Throughput/Combinatorial Screening of Hydrogen Storage Materials...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

High ThroughputCombinatorial Screening of Hydrogen Storage Materials (presentation) High ThroughputCombinatorial Screening of Hydrogen Storage Materials (presentation) Presented...

12

High Throughput Operando Studies using Fourier Transform Infrared...  

NLE Websites -- All DOE Office Websites (Extended Search)

Throughput Operando Studies using Fourier Transform Infrared Imaging and Raman Spectroscopy. High Throughput Operando Studies using Fourier Transform Infrared Imaging and Raman...

13

High Throughput/Combinatorial Screening of Hydrogen Storage Materials...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

ThroughputCombinatorial Screening of Hydrogen Storage Materials: UOP Approaches High ThroughputCombinatorial Screening of Hydrogen Storage Materials: UOP Approaches Presentation...

14

494 IEEE TRANSACTIONS ON VERY LARGE SCALE INTEGRATION (VLSI) SYSTEMS, VOL. 13, NO. 4, APRIL 2005 Memory Sub-Banking Scheme for High Throughput  

E-Print Network (OSTI)

decoding latency, and reduced memory energy consumption. Our contributions include deriva- tion, and energy consumption and provide a tradeoff analysis between the different parameters. The main implementations (both single port and dual port) of the SW SISO decoder that achieves high throughput, low

Kambhampati, Subbarao

15

Determination of Monomethylhydrazine with a High-Throughput, All-Fiber Near-Infrared  

E-Print Network (OSTI)

Determination of Monomethylhydrazine with a High-Throughput, All-Fiber Near-Infrared Spectrometer-throughput near-infrared spectrophotometer has been successfully constructed by synergistic use of this integrated and wide spectral band- width in the near-infrared region from 1500 to 1600 nm. This spectral region

Reid, Scott A.

16

High throughput chemical munitions treatment system  

SciTech Connect

A new High-Throughput Explosive Destruction System is disclosed. The new system is comprised of two side-by-side detonation containment vessels each comprising first and second halves that feed into a single agent treatment vessel. Both detonation containment vessels further comprise a surrounding ventilation facility. Moreover, the detonation containment vessels are designed to separate into two half-shells, wherein one shell can be moved axially away from the fixed, second half for ease of access and loading. The vessels are closed by means of a surrounding, clam-shell type locking seal mechanisms.

Haroldsen, Brent L. (Manteca, CA); Stofleth, Jerome H. (Albuquerque, NM); Didlake, Jr., John E. (Livermore, CA); Wu, Benjamin C-P (San Ramon, CA)

2011-11-01T23:59:59.000Z

17

High Throughput/Combinatorial Screening of Hydrogen Storage Materials...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Workshop HIGH THROUGHPUTCOMBINATORIAL SCREENING OF HYDROGEN STORAGE MATERIALS June 26, 2007 Tom Boussie Symyx Technologies Symyx develops and applies proprietary high-throughput...

18

Potential of High-Throughput Experimentation with Ammonia Borane...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

of High-Throughput Experimentation with Ammonia Borane Solid Hydrogen Storage Materials Jonathan L. Male Pacific Northwest National Laboratory June 26, 2006 US Department of Energy...

19

High Throughput Combinatorial Screening of Biometic Metal-Organic...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Throughput Combinatorial Screening of Biometic Metal-Organic Materials for Military Hydrogen-Storage Materials (New Joint Miami UNREL DoDDLA Project) (presentation) High...

20

Application of high-throughput computing in bioinformatics  

Science Journals Connector (OSTI)

...Issue New science from high-performance computing organized by Richard Catlow...bioinformatics database|high-performance computing| Application of high-throughput...bioinformatics database; high-performance computing 1. Introduction Organizing...

2002-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "integrated high throughput" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


21

ORIGINAL ARTICLE Combining high-throughput sequencing with fruit  

E-Print Network (OSTI)

ORIGINAL ARTICLE Combining high-throughput sequencing with fruit body surveys reveals contrasting communities were mostly confined to fruit bodies, whereas mycelial interactions were studied in the laboratory. Here we combine high-throughput sequencing with a fruit body inventory to study simultaneously mycelial

Bruns, Tom

22

Microfluidic Technologies for High-Throughput Screening Applications  

E-Print Network (OSTI)

Microfluidic Technologies for High-Throughput Screening Applications Thesis by Todd Thorsen, patiently giving me advice on a large variety of subjects, ranging from microfluidics to optics of microfluidic devices for high-throughput screening applications, such as mutant enzyme libraries expressed

Quake, Stephen R.

23

High-Throughput/Combinatorial Techniques in Hydrogen Storage...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Storage (New DoDDLA Project), Ali T-Raissi, University of Central Florida, Florida Solar Energy Center High-Throughput Methodology for Discovery of Metal-Organic Frameworks...

24

High-throughput routing for multi-hop wireless networks  

E-Print Network (OSTI)

The expected transmission count (ETX) metric is a new route metric for finding high-throughput paths in multi-hop wireless networks. The ETX of a path is the expected total number of packet transmissions (including ...

De Couto, Douglas S. J. (Douglas Seraphim James), 1975-

2004-01-01T23:59:59.000Z

25

High-Throughput Characterization of Porous Materials Using Graphics...  

NLE Websites -- All DOE Office Websites (Extended Search)

High-Throughput Characterization of Porous Materials Using Graphics Processing Units Previous Next List J. Kim, R. L. Martin, O. Rubel, M. Haranczyk, and B. Smit, J. Chem. Theory...

26

Robust, High-Throughput Analysis of Protein Structures  

NLE Websites -- All DOE Office Websites (Extended Search)

of even the simplest of organisms. Hura et al. have developed a high-throughput protein pipeline that could expedite protein analysis by trading atomic-level detail for speed and...

27

Development and optimization of high-throughput zebrafish screening platform  

E-Print Network (OSTI)

The high-throughput zebrafish screening platform is a revolutionary tool that enables subcellular precision in vivo whole animal screening of Danio Rerio. It can perform laser surgery and/or imaging in less than twenty ...

Koo, Bryan Kyo

2010-01-01T23:59:59.000Z

28

High-throughput vertebrate total analysis/screening platform  

E-Print Network (OSTI)

High-throughput screening (HTS) is seen as one of the most promising technologies to facilitate biomedical studies and pharmaceutical discoveries. Although large varieties of in vitro HTS technologies have opened great ...

Chang, Tsung-Yao, Ph. D. Massachusetts Institute of Technology

2012-01-01T23:59:59.000Z

29

Macromolecular Crystallography conventional and high-throughput methods  

SciTech Connect

High-throughput data collection requires the seamless interoperation of various hardware components. User-supplied descriptions of protein crystals must also be directly linked with the diffraction data. Such linkages can be achieved efficiently with computer databases. A database that tracks production of the protein samples, crystallization, and diffraction from the resultant crystals serves as the glue that holds the entire gene-to-structure process together. This chapter begins by discussing data collection processes and hardware. It then illustrates how a well-constructed database ensures information flow through the steps of data acquisition. Such a database allows synchrotron beamline measurements to be directly and efficiently integrated into the process of protein crystallographic structure determination.

Wasserman, Stephen R.; Smith, David W.; D'Amico, Kevin L.; Koss, John W.; Morisco, Laura L.; Burley, Stephen K.

2007-09-27T23:59:59.000Z

30

High Throughput Screening of Biologically Functional Small Molecules for Modulating the Expression of FGFR1OP2/wit3.0 in Fibroblasts  

E-Print Network (OSTI)

chemical in our final high throughput assay platform.platform. High Throughput Assay Optimization Most chemicals

Cheng, William J.

2012-01-01T23:59:59.000Z

31

High Throughput Spectrum-aware Routing for Cognitive Radio Networks  

E-Print Network (OSTI)

High Throughput Spectrum-aware Routing for Cognitive Radio Networks Ashwin Sampath, Lei Yang, Lili, wireless nodes equipped with cognitive radios [11] do not operate on statically as- signed spectrum who own the spectrum, e.g. analog TV broadcast stations. Such flexibility means cognitive radios can

Zhao, Ben Y.

32

High Throughput Spectrumaware Routing for Cognitive Radio Networks  

E-Print Network (OSTI)

High Throughput Spectrum­aware Routing for Cognitive Radio Networks Ashwin Sampath, Lei Yang, Lili, wireless nodes equipped with cognitive radios [11] do not operate on statically as­ signed spectrum. Instead, they identify and use locally unused licensed spectrum while avoiding disruptions to legacy users

Zhao, Ben Y.

33

The JCSG high-throughput structural biology pipeline  

Science Journals Connector (OSTI)

The Joint Center for Structural Genomics high-throughput structural biology pipeline has delivered more than 1000 structures to the community over the past ten years and has made a significant contribution to the overall goal of the NIH Protein Structure Initiative (PSI) of expanding structural coverage of the protein universe.

Elsliger, M.-A.

2010-09-30T23:59:59.000Z

34

Abstract 3967: The Cancer Genome Project high throughput analysis pipeline  

Science Journals Connector (OSTI)

...Genome Project high throughput analysis pipeline Adam P. Butler 1 Jon W. Teague 1 Keiran...somatic changes. We have built an analysis pipeline to track and analyse large numbers of...externally available tools. The analysis pipeline is built around a 2,000 node compute...

Adam P. Butler; Jon W. Teague; Keiran M. Raine; Andrew Menzies; David Jones; John Marshall; Jon Hinton; Serge Dronov; John Gamble; Lucy Stebbings; Alagu Jayakumar; Catherine Leroy; Ultan McDermott; Michael R. Stratton; Peter Campbell; Andy Futreal

2012-06-04T23:59:59.000Z

35

High-throughput proteomics : optical approaches.  

SciTech Connect

Realistic cell models could greatly accelerate our ability to engineer biochemical pathways and the production of valuable organic products, which would be of great use in the development of biofuels, pharmaceuticals, and the crops for the next green revolution. However, this level of engineering will require a great deal more knowledge about the mechanisms of life than is currently available. In particular, we need to understand the interactome (which proteins interact) as it is situated in the three dimensional geometry of the cell (i.e., a situated interactome), and the regulation/dynamics of these interactions. Methods for optical proteomics have become available that allow the monitoring and even disruption/control of interacting proteins in living cells. Here, a range of these methods is reviewed with respect to their role in elucidating the interactome and the relevant spatial localizations. Development of these technologies and their integration into the core competencies of research organizations can position whole institutions and teams of researchers to lead in both the fundamental science and the engineering applications of cellular biology. That leadership could be particularly important with respect to problems of national urgency centered around security, biofuels, and healthcare.

Davidson, George S.

2008-09-01T23:59:59.000Z

36

High-Throughput and Combinatorial Screening  

E-Print Network (OSTI)

, for the United States Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL Theory guidance: Monte Carlo (MC) technique provides minimum energy structures for subsequent enthalpy (Germany), Stockholm University (Sweden), IFE (Norway), SRNL (USA), U. Tohoku, AIST (Japan) #12;High

37

Methods and technologies for high-throughput and high-content small animal screening  

E-Print Network (OSTI)

High-throughput and high-content screening (HTS and HCS) of whole animals requires their immobilization for high-resolution imaging and manipulation. Here we present methods to enable HTS and HCS of the nematode Caenorhabditis ...

Rohde, Christopher, 1979-

2012-01-01T23:59:59.000Z

38

Towards Chip Scale Liquid Chromatography and High Throughput Immunosensing  

SciTech Connect

This work describes several research projects aimed towards developing new instruments and novel methods for high throughput chemical and biological analysis. Approaches are taken in two directions. The first direction takes advantage of well-established semiconductor fabrication techniques and applies them to miniaturize instruments that are workhorses in analytical laboratories. Specifically, the first part of this work focused on the development of micropumps and microvalves for controlled fluid delivery. The mechanism of these micropumps and microvalves relies on the electrochemically-induced surface tension change at a mercury/electrolyte interface. A miniaturized flow injection analysis device was integrated and flow injection analyses were demonstrated. In the second part of this work, microfluidic chips were also designed, fabricated, and tested. Separations of two fluorescent dyes were demonstrated in microfabricated channels, based on an open-tubular liquid chromatography (OT LC) or an electrochemically-modulated liquid chromatography (EMLC) format. A reduction in instrument size can potentially increase analysis speed, and allow exceedingly small amounts of sample to be analyzed under diverse separation conditions. The second direction explores the surface enhanced Raman spectroscopy (SERS) as a signal transduction method for immunoassay analysis. It takes advantage of the improved detection sensitivity as a result of surface enhancement on colloidal gold, the narrow width of Raman band, and the stability of Raman scattering signals to distinguish several different species simultaneously without exploiting spatially-separated addresses on a biochip. By labeling gold nanoparticles with different Raman reporters in conjunction with different detection antibodies, a simultaneous detection of a dual-analyte immunoassay was demonstrated. Using this scheme for quantitative analysis was also studied and preliminary dose-response curves from an immunoassay of a mo del antigen were obtained. Simultaneous detection of several analytes at the same address can potentially increase the analysis speed, and can further expand the analysis capability of a microarray chip.

Ni, J.

2000-09-21T23:59:59.000Z

39

Grid Workflow Software for a High-Throughput Proteome Annotation Pipeline  

E-Print Network (OSTI)

Grid Workflow Software for a High-Throughput Proteome Annotation Pipeline Adam Birnbaum1 , James-Throughput Proteome 69 Protein Data Bank [9]. Despite the advent of high throughput crystallization pipelines [25 Annotation Pipeline (iGAP) [28]. iGAP, which incorporates a number of well established bioinformatics

Bourne, Philip E.

40

PIPA: A High-Throughput Pipeline for Protein Function Annotation Chenggang Yu, Valmik Desai, Nela Zavaljevski, and Jaques Reifman  

E-Print Network (OSTI)

PIPA: A High-Throughput Pipeline for Protein Function Annotation Chenggang Yu, Valmik Desai, Nela of multisource predictions. We developed Pipeline for Protein Annotation (PIPA), a genome-wide protein function annotation pipeline that runs in a high-performance computing environment. PIPA integrates different tools

Note: This page contains sample records for the topic "integrated high throughput" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


41

Inch-Scale High Throughput Metrology of Graphene and Patterned Graphene Oxide.  

E-Print Network (OSTI)

??Abstract Inch-Scale High Throughput Metrology of Graphene and Patterned Graphene Oxide by Dennis Pleskot Master of Science, Graduate Program in Materials Science and Engineering University (more)

Pleskot, Dennis

2013-01-01T23:59:59.000Z

42

The high-throughput protein-to-structure pipeline at SECSG  

Science Journals Connector (OSTI)

The high-throughput crystal structure determination pipeline at Southeast Collaboratory for Structural Genomics, a pilot center of the National Institutes of Health Protein Structure Initiative, is described.

Liu, Z.-J.

2005-05-26T23:59:59.000Z

43

High-Throughput Microfluidics and Ultrafast Optics for in vivo Compound/Genetic Discoveries  

Science Journals Connector (OSTI)

We developed microfluidic and ultrafast optical technologies that enable high-throughput whole-animal neural regeneration studies. These technologies allow automated and rapid...

Rohde, Chris; Gilleland, Cody; Samara, Chrysanthi; Yanik, Mehmet F

44

A microfluidic platform for high-throughput multiplexed protein quantitation  

E-Print Network (OSTI)

We present a high-throughput microfluidic platform capable of quantitating up to 384 biomarkers in 4 distinct samples by immunoassay. The microfluidic device contains 384 unit cells, which can be individually programmed with pairs of capture and detection antibody. Samples are quantitated in each unit cell by four independent MITOMI detection areas, allowing four samples to be analyzed in parallel for a total of 1,536 assays per device. We show that the device can be pre-assembled and stored for weeks at elevated temperature and we performed proof-of-concept experiments simultaneously quantitating IL-6, IL-1\\b{eta}, TNF-{\\alpha}, PSA, and GFP. Finally, we show that the platform can be used to identify functional antibody combinations by screening 64 antibody combinations requiring up to 384 unique assays per device.

Volpetti, Francesca; Maerkl, Sebastian

2014-01-01T23:59:59.000Z

45

HIGH-THROUGHPUT/COMBINATORIAL TECHNIQUES IN HYDROGEN STORAGE MATERIALS R&D WORKSHOP  

E-Print Network (OSTI)

HIGH-THROUGHPUT/COMBINATORIAL TECHNIQUES IN HYDROGEN STORAGE MATERIALS R&D WORKSHOP U.S. Department 26, 2007, DOE's Hydrogen Storage Program held a one-day High- Throughput/Combinatorial Techniques in Hydrogen Storage Materials R&D meeting to identify how to better implement high

46

Abstract 5143: From sequencing data to mutation spectra: a high throughput analysis pipeline.  

Science Journals Connector (OSTI)

...spectra: a high throughput analysis pipeline. David Jones Adam P. Butler Jon W...developed a high throughput analysis pipeline utilising a suite of analysis software...development is focussed on converting the pipeline to produce and store VCF output, incorporate...

David Jones; Adam P. Butler; Jon W. Teague; Keiran M. Raine; Andrew Menzies; John Marshall; Jonathan Hinton; Serge Dronov; Lucy Stebbings; Alagu Jayakumar; Catherine Leroy; Jorge Zamora; Manasa Ramakrishna; Elli Papaemmanuil; Helen Davies; Susanna L. Cooke; Serena Nik-Zainal; Ultan McDermott; Michael R. Stratton; Peter Campbell

2013-08-14T23:59:59.000Z

47

High-throughput metal nanoparticle catalysis by pulsed laser ablation Selim Senkan a,*, Michael Kahn a  

E-Print Network (OSTI)

High-throughput metal nanoparticle catalysis by pulsed laser ablation Selim Senkan a,*, Michael online 18 July 2006 Abstract A high-throughput pulsed laser ablation (HT-PLA) system was developed-TEM) and energy dispersive X-ray (EDX) spectroscopy, respectively. The supported nanoparticles created by HT

Senkan, Selim M.

48

High-Throughput/Combinatorial Techniques in Hydrogen Storage...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

ThroughputCombinatorial Techniques in Hydrogen Storage Materials R&D Ned Stetson, Larry Blair 1 , Grace Ordaz, Carole Read, George Thomas 2 , and Sunita Satyapal Suite 900, 7475...

49

FastForward: High-Throughput Dual-Radio Streaming Gholamhossein Ekbatanifard  

E-Print Network (OSTI)

amount of data at high throughput and/or low latency. For example, structural health of the Golden Gate end-to-end throughput is limited to 1/2 the radio capacity. To bridge this performance gap we present Bridge was sampled at 1 KHz in [1]. Brimon, a railway monitoring system, generates about 7 KB in each

Kuzmanov, Georgi

50

High-throughput analysis of thin-film stresses using arrays of micromachined cantilever beams  

E-Print Network (OSTI)

High-throughput analysis of thin-film stresses using arrays of micromachined cantilever beams Hyun-throughput residual stress measurements on thin films by means of micromachined cantilever beams and an array of parallel laser beams. In this technique, the film of interest is deposited onto a silicon substrate

51

Heterogeneous High Throughput Scientific Computing with APM X-Gene and Intel Xeon Phi  

E-Print Network (OSTI)

Electrical power requirements will be a constraint on the future growth of Distributed High Throughput Computing (DHTC) as used by High Energy Physics. Performance-per-watt is a critical metric for the evaluation of computer architectures for cost- efficient computing. Additionally, future performance growth will come from heterogeneous, many-core, and high computing density platforms with specialized processors. In this paper, we examine the Intel Xeon Phi Many Integrated Cores (MIC) co-processor and Applied Micro X-Gene ARMv8 64-bit low-power server system-on-a-chip (SoC) solutions for scientific computing applications. We report our experience on software porting, performance and energy efficiency and evaluate the potential for use of such technologies in the context of distributed computing systems such as the Worldwide LHC Computing Grid (WLCG).

David Abdurachmanov; Brian Bockelman; Peter Elmer; Giulio Eulisse; Robert Knight; Shahzad Muzaffar

2014-10-10T23:59:59.000Z

52

Heterogeneous High Throughput Scientific Computing with APM X-Gene and Intel Xeon Phi  

E-Print Network (OSTI)

Electrical power requirements will be a constraint on the future growth of Distributed High Throughput Computing (DHTC) as used by High Energy Physics. Performance-per-watt is a critical metric for the evaluation of computer architectures for cost- efficient computing. Additionally, future performance growth will come from heterogeneous, many-core, and high computing density platforms with specialized processors. In this paper, we examine the Intel Xeon Phi Many Integrated Cores (MIC) co-processor and Applied Micro X-Gene ARMv8 64-bit low-power server system-on-a-chip (SoC) solutions for scientific computing applications. We report our experience on software porting, performance and energy efficiency and evaluate the potential for use of such technologies in the context of distributed computing systems such as the Worldwide LHC Computing Grid (WLCG).

Abdurachmanov, David; Elmer, Peter; Eulisse, Giulio; Knight, Robert; Muzaffar, Shahzad

2014-01-01T23:59:59.000Z

53

E-Print Network 3.0 - alphascreen high-throughput assay Sample...  

NLE Websites -- All DOE Office Websites (Extended Search)

Session Chair: James F. Leary 3:20-4:05 James F. Leary, "High throughput cell analysis... French and Jiyan Chen Long Lifetime Measurements in High ... Source: Xu, X. Nancy -...

54

Agenda from the U.S. Department of Energy's High Throughput Screening...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Agenda from the U.S. Department of Energy's High Throughput Screening of Hydrogen Storage Materials Workshop on June 26, 2007 Agenda from the U.S. Department of Energy's High...

55

High-throughput manufacturing of thin-film CdTe photovoltaic modules  

Science Journals Connector (OSTI)

The main obstacle to the wide spread use of photovoltaics as a major source of renewable energy has been cost. The key to lowering the cost of photovoltaic generated energy to the levels of conventional sources of energy lays in the development of low cost high throughput manufacturing processes. Solar Cells Inc. (SCI) believes this can be achieved for CdTe based modules by integrating its PV fabrication processes with a modern glass plant. That is sand in finished module out. It is also necessary to have a stable end product in order to gain wide acceptance. SCI has been working at producing large-area CdS/CdTe photovoltaic (PV) modules and the processes developed at SCI can be scaled to achieve high production levels at cost-effective rates.

Alan McMaster; Steve Johnson

1999-01-01T23:59:59.000Z

56

Low inlet gas velocity high throughput biomass gasifier  

DOE Patents (OSTI)

The present invention discloses a novel method of operating a gasifier for production of fuel gas from carbonaceous fuels. The process disclosed enables operating in an entrained mode using inlet gas velocities of less than 7 feet per second, feedstock throughputs exceeding 4000 lbs/ft.sup.2 -hr, and pressures below 100 psia.

Feldmann, Herman F. (Worthington, OH); Paisley, Mark A. (Upper Arlington, OH)

1989-01-01T23:59:59.000Z

57

Discovery and High-Throughput Screening of Heteroleptic Iridium Complexes for Photoinduced Hydrogen Production  

E-Print Network (OSTI)

high-throughput photophysical techniques, to identify six potential photosensitizers for use researchers. Simple solar devices focus or collect sunlight, harnessing radiation in order to heat dwellings or drive turbines. Photovoltaic cells can convert solar radiation directly to electrical current

Bernhard, Stefan

58

A microfluidic device for high throughput bacterial biofilm studies Jeongyun Kim,a  

E-Print Network (OSTI)

A microfluidic device for high throughput bacterial biofilm studies Jeongyun Kim,a Manjunath Hegde of biofilm community formation. Here, we describe the development of a PDMS-based two-layer microfluidic flow

Wood, Thomas K.

59

High-Throughput/Combinatorial Techniques in Hydrogen Storage Materials R&D  

Energy.gov (U.S. Department of Energy (DOE))

On June 26, 2007 the Hydrogen Storage Program of the U.S. Department of Energy (DOE) held a one-day meeting to identify how to better implement high-throughput/combinatorial techniques to benefit...

60

An instrument for high-throughput measurements of fiber mechanical properties  

E-Print Network (OSTI)

In this thesis, an instrument is designed and constructed for the purpose of measuring the mechanical properties of single fibers. The instrument is intended to provide high throughput measurement of single fiber geometric ...

Kristofek, Grant William, 1980-

2005-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "integrated high throughput" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


61

Development of High-Throughput Microfluidic Impedance Spectroscopy Platform for Analyzing Microdroplets in Droplet Microfluidic System  

E-Print Network (OSTI)

This thesis presents the development of a high-throughput microfluidic impedance spectroscopy platform for electrically detecting analyzing impedance measurements of non-contact and label free microdroplets. This microfluidic impedance spectroscopy...

Sobahi, Nebras MohammedKamal A.

2014-07-22T23:59:59.000Z

62

Engineering a single cell microarray platform for high throughput DNA damage and repair analysis  

E-Print Network (OSTI)

DNA damage contributes to cancer, aging, and heritable diseases. Ironically, DNA damaging agents are also commonly used in current cancer treatment. We therefore need robust, high throughput, and inexpensive tools for ...

Weingeist, David McGregor

2012-01-01T23:59:59.000Z

63

Optical Multiplexing for High-Throughput Spectroscopic Analysis.  

E-Print Network (OSTI)

in optical biosensor testing as it provides greater throughput and scalability while being an economical and compact solution. v NOMENCLATURE MFPF Multi Frequency Phase Fluorometer MUX Multiplexer LED Light Emitting Diode DIO Digital Input... oxidase in hybrid silicate microsphere that is coated with nanofilm and reference dye (RITC) (Fig. 1) [2]. The phosphorescent dye is excited by a green light from a LED (light emitting diode) to emit luminescence, the intensity of which is dependent...

Ahmed, Saadiah

2012-05-03T23:59:59.000Z

64

Erythrocyte deformation in high-throughput optical stretchers  

Science Journals Connector (OSTI)

Optical stretchers can be used to quantify elastic and homeostatic properties of cells. Because they can apply forces to cells without requiring direct contact, they may noninvasively measure mechanical properties related to cell and membrane health. Present-day optical stretchers are, however, limited to measurements on individual stationary cells, limiting throughput. To overcome this limitation and allow study of variations in cell populations, we recently developed and tested a microfluidic chamber that measures optical stretching parameters for erythrocytes under dynamic flowing conditions. The method uses a single linear diode laser bar and permitted measurements at low flow rates and higher throughput. Here, we numerically investigate the feasibility of further increasing the measurement rates of the optical stretcher in parameter domains where hydrodynamic and optical forces are of comparable magnitude. To do this we couple a recently implemented dynamic optical ray-tracing technique with a fluid-structure interaction solver to simulate the deformation of osmotically swollen erythrocytes in fluid flow of variable rate. Our results demonstrate that a detectable steady-state stretch is induced at nominal optical powers and flow rates. In addition, we find that flow rates can be increased significantly with no major effect on net cell stretch showing the feasibility of application of this technique at greatly increased throughputs.

Ihab Sraj; Alex C. Szatmary; Sanjay A. Desai; David W. M. Marr; Charles D. Eggleton

2012-04-30T23:59:59.000Z

65

A High Through-put Combinatorial Growth Technique for Semiconductor Thin Film Search  

SciTech Connect

Conventional semiconductor material growth technique is costly and time-consuming. Here we developed a new method to growth semiconductor thin films using high through-put combinatorial technique. In this way, we have successfully fabricated tens of semiconductor libraries with high crystallinity and high product of {mu}{tau} for the purpose of radiation detection.

Ma, Z. X.; Hao, H. Y.; Xiao, P.; Oehlerking, L. J.; Liu, D. F.; Zhang, X. J.; Yu, K.-M.; Walukiewicz, W.; Mao, S. S. [Lawrence Berkeley National Laboratory, Berkeley, CA 94720 (United States); Yu, P. Y. [Lawrence Berkeley National Laboratory, Berkeley, CA 94720 (United States); Department of Physics, University of California, Berkeley, CA 94720 (United States)

2011-12-23T23:59:59.000Z

66

Salvage and storage of infectious disease protein targets in the SSGCID high-throughput crystallization pathway using microfluidics  

Science Journals Connector (OSTI)

SSGCID protein crystals were salvaged and stored using the MPCS Plug Maker and CrystalCards when high-throughput traditional sitting-drop vapor diffusion initially failed.

Christensen, J.

2011-08-13T23:59:59.000Z

67

High-Throughput Screening Technique for Biomass Conversion in Hot Compressed Water  

Science Journals Connector (OSTI)

High-Throughput Screening Technique for Biomass Conversion in Hot Compressed Water ... Formic acid is known to be converted completely to gaseous products, mainly CO2 and H2 at high temperatures. ... The Ru/TiO2 catalyst is able to convert WSIS (char) to gas, while leaving the oil product practically unaltered with respect to compn. ...

Pavlina Nanou; Wim P. M. van Swaaij; Sascha R. A. Kersten; Guus van Rossum

2012-01-17T23:59:59.000Z

68

Hydrogen Storage Materials Discovery via High Throughput Ball Milling and Gas Sorption  

Science Journals Connector (OSTI)

The lack of a high capacity hydrogen storage material is a major barrier to the implementation of the hydrogen economy. To accelerate discovery of such materials, we have developed a high-throughput workflow for screening of hydrogen storage materials in ...

Bin Li; Steven S. Kaye; Conor Riley; Doron Greenberg; Daniel Galang; Mark S. Bailey

2012-05-22T23:59:59.000Z

69

A Warm Near-Infrared High-Resolution Spectrograph with Very High Throughput (WINERED)  

E-Print Network (OSTI)

WINERED is a newly built high-efficiency (throughput$ > 25-30\\%$) and high-resolution spectrograph customized for short NIR bands at 0.9-1.35 ${\\rm \\mu}$m. WINERED is equipped with ambient temperature optics and a cryogenic camera using a 1.7 ${\\rm \\mu}$m cut-off HgCdTe HAWAII-2RG array detector. WINERED has two grating modes: one with a conventional reflective echelle grating (R$\\sim$28,300), which covers 0.9-1.35 $\\mu$m simultaneously, the other with ZnSe or ZnS immersion grating (R$\\sim$100,000). We have completed the development of WINERED except for the immersion grating, and started engineering and science observations at the Nasmyth platform of the 1.3 m Araki Telescope at Koyama Astronomical Observatory of Kyoto-Sangyo University in Japan. We confirmed that the spectral resolution ($R\\sim$ 28,300) and the throughput ($>$ 40\\% w/o telescope/atmosphere/array QE) meet our specifications. We measured ambient thermal backgrounds (e.g., 0.06 ${\\rm [e^{-}/sec/pixel]}$ at 287 K), which are roughly consistent ...

Kondo, Sohei; Kobayashi, Naoto; Yasui, Chikako; Mito, Hiroyuki; Fukue, Kei; Nakanishi, Kenshi; Kawanishi, Takafumi; Nakaoka, Tetsuya; Otsubo, Shogo; Kinoshita, Masaomi; Kitano, Ayaka; Hamano, Satoshi; Mizumoto, Misaki; Yamamoto, Ryo; Izumi, Natsuko; Matsunaga, Noriyuki; Kawakita, Hideyo

2015-01-01T23:59:59.000Z

70

HIGH-THROUGHPUT COOPERATIVE TRANSMISSIONS USING ADAPTIVE COMPLEX-FIELD NETWORK CODING  

E-Print Network (OSTI)

HIGH-THROUGHPUT COOPERATIVE TRANSMISSIONS USING ADAPTIVE COMPLEX-FIELD NETWORK CODING Guobing Li1 , Alfonso Cano2 , and Georgios B. Giannakis2 1 School of Elect. and Info. Engr., Xi'an Jiaotong University. In this pa- per, a novel cooperation protocol is developed based on adap- tive complex-field wireless network

Pleite, Alfonso Cano

71

ORIGINAL ARTICLE GeoChip 3.0 as a high-throughput tool for analyzing  

E-Print Network (OSTI)

significantly changed with the plant species diversity. As expected, GeoChip 3.0 is a high-throughput powerful Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA and 8 Virtual Institute Keywords: microarray; functional genes; microbial community; plant diversity Introduction Microorganisms

Hazen, Terry

72

ORIGINAL ARTICLE GeoChip 3.0 as a high-throughput tool for analyzing  

E-Print Network (OSTI)

significantly changed with the plant species diversity. As expected, GeoChip 3.0 is a high-throughput powerful Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA and 8 Virtual Institute in microbial ecology Keywords: microarray; functional genes; microbial community; plant diversity Introduction

Weiblen, George D

73

Treatability studies on different refinery wastewater samples using high-throughput microbial electrolysis cells (MECs)  

E-Print Network (OSTI)

, 2005), brewery (Feng et al., 2008), animal (Min et al., 2005) and paper recycling wastewaters (HuangTreatability studies on different refinery wastewater samples using high-throughput microbial, University Park, PA 16802, USA h i g h l i g h t s Refinery wastewaters were tested as fuels in MECs

74

Database Requirements for Workflow Management in a HighThroughput Genome Laboratory 1  

E-Print Network (OSTI)

Database Requirements for Workflow Management in a High­Throughput Genome Laboratory 1 Anthony J and operationally efficient. A key component of this software is a database management system (DBMS) for controlling constitutes an audit trail, or event history, and has much the same function as a laboratory notebook

Bonner, Anthony

75

Sample collection for high throughput radiation biodosimetry , H.C. Turner1  

E-Print Network (OSTI)

fingerstick-derived blood samples, either to estimate past radiation dose, or to sort individuals exposed, there will be a major need to assess, within a few days, the radiation doses received by tens or hundreds of thousandsSample collection for high throughput radiation biodosimetry G. Garty1 , H.C. Turner1 , Y. Chen2

Simaan, Nabil

76

WebPSN: a web server for high-throughput investigation of structural communication in biomacromolecules  

Science Journals Connector (OSTI)

......brief-report Applications Note WebPSN: a web server for high-throughput investigation...implemented WebPSN, a freely available web server that allows the user to easily setup...the method was therefore implemented in a web server (WebPSN) that provides the user......

Michele Seeber; Angelo Felline; Francesco Raimondi; Simona Mariani; Francesca Fanelli

2014-11-01T23:59:59.000Z

77

High-throughput imaging of heterogeneous cell organelles with an X-ray laser  

DOE Data Explorer (OSTI)

Preprocessed detector images that were used for the paper "High-throughput imaging of heterogeneous cell organelles with an X-ray laser". The CXI file contains the entire recorded data - including both hits and blanks. It also includes down-sampled images and LCLS machine parameters. Additionally, the Cheetah configuration file is attached that was used to create the pre-processed data.

Hantke, Max, F.

78

High-throughput single-molecule fluorescence spectroscopy using parallel detection  

E-Print Network (OSTI)

High-throughput single-molecule fluorescence spectroscopy using parallel detection X. Michalet Solution-based single-molecule fluorescence spectroscopy is a powerful new experimental approach in rare burst-like events corresponding to the transit of a single-molecule. Those events are accumulated

Michalet, Xavier

79

MATRIX 1 RESULTS OF THE FY07 ENHANCED DOE HIGH-LEVEL WASTE MELTER THROUGHPUT STUDIES AT SRNL  

SciTech Connect

High-level waste (HLW) throughput (i.e., the amount of waste processed per unit time) is a function of two critical parameters: waste loading (WL) and melt rate. For the Waste Treatment and Immobilization Plant (WTP) at the Hanford Site and the Defense Waste Processing Facility (DWPF) at the Savannah River Site (SRS), increasing HLW throughput would significantly reduce the overall mission life cycle costs for the Department of Energy (DOE). It has been proposed that a team of glass formulation and processing experts at the Pacific Northwest National Laboratory (PNNL), Savannah River National Laboratory (SRNL), and Vitreous State Laboratory (VSL) at Catholic University of America develop a systematic approach to increase HLW throughput (by increasing WL with minimal or positive impacts on melt rate). Programmatically, this task is aimed at proof-of-principle testing and the development of tools to improve waste loading and melt rate, which will lead to higher waste throughput. The following four specific tasks have been proposed to meet this programmatic objective: (1) Integration and Oversight, (2) Crystal Accumulation Modeling (led by PNNL)/Higher Waste Loading Glasses (led by SRNL), (3) Melt Rate Evaluation and Modeling, and (4) Melter Scale Demonstrations. The details of these tasks can be found in the associated task plan WSRC-STI-2007-00483. The current study is focused on Task 2 (crystal accumulation modeling and higher waste loading glasses) and involves glass formulation and physical property testing by both PNNL and SRNL (as defined in the PNNL and SRNL test plans). The intent of this report is to document the chemical composition and Product Consistency Test (PCT) results and statistical analysis of PNNL's Test Matrix 1 glasses. Note that this document is only a compilation of the data collected by SRNL for PNNL's glasses in support of this task and no conclusions will be drawn.

Raszewski, F; Tommy Edwards, T; David Peeler, D

2008-09-23T23:59:59.000Z

80

Systematic reconstruction of RNA functional motifs with high throughput microfluidics  

E-Print Network (OSTI)

-quarters of the human genome is capable of being transcribed1. Because only ~1.5% of the genome encodes for protein, non specificities and enriches interpretation of phylogenetic data. The ENCODE project has shown that three-coding RNAs (ncRNAs) may be a highly abundant output of genetic information. ncRNAs can exert epigenetic

Quake, Stephen R.

Note: This page contains sample records for the topic "integrated high throughput" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


81

Directed Enzyme Evolution and High-Throughput Screening  

E-Print Network (OSTI)

into a commercial process relies on the availability of those with high activity and stability under process optimization process, whereby the fittest variants are selected from an ensemble of mutants [3]. Directed for process scientists today. Choosing the appropriate methods of library generation and screening

Zhao, Huimin

82

Integrated microbioreactor arrays for high-throughput experimentation  

E-Print Network (OSTI)

Bioprocesses with microbial cells play an important role in producing biopharmaceuticals such as human insulin and human growth hormone, and other products such as amino acids and biopolymers. Because bioprocesses involve ...

Lee, Harry, 1976-

2006-01-01T23:59:59.000Z

83

Development of Quantitative FRET Technology for SENP Enzyme Kinetics Determinations and High-Sensitive High-Throughput Screening Assay for Protease Inhibitor Discovery  

E-Print Network (OSTI)

chemical inhibitors as a high-throughput screening platform.platform, in which the disruption of SENP towards pre-SUMOs maturation by small chemical

Liu, Yan

2012-01-01T23:59:59.000Z

84

High throughput lessons from the LHC experience.Johnston.TNC2013  

NLE Websites -- All DOE Office Websites (Extended Search)

high throughput in widely distributed data high throughput in widely distributed data management and analysis systems: Lessons from the LHC William E. Johnston ESnet, Lawrence Berkeley National Laboratory e-mail: wej@es.net Eli Dart ESnet, Lawrence Berkeley National Laboratory e-mail: dart@es.net Michael Ernst RHIC and ATLAS Computing Facility, Brookhaven National Laboratory e-mail: mernst@bnl.gov Brian Tierney ESnet, Lawrence Berkeley National Laboratory e-mail: bltierney@es.net Paper type Technical paper Abstract Today's large-scale science projects all involve world-wide collaborations that must routinely move 10s of petabytes per year between international sites in order to be successful. This is true for the two largest experiments at the Large Hadron Collider (LHC) at CERN - ATLAS and CMS - and for the climate science

85

Reading Dynamic Kinase Activity in Living Cells for High-Throughput Screening  

Science Journals Connector (OSTI)

Here, we describe a general method for high-throughput reading of dynamic kinase activities using ratiometric fluorescent sensors, and showcase an example of reading intracellular activities of protein kinase A (PKA) and the cyclic adenosine monophosphate (cAMP)/PKA pathway downstream of many G-protein coupled receptors (GPCRs). ... Kinases are crucial nodes in the signaling network and emerging drug targets of the 21st century (1). ...

Michael D. Allen; Lisa M. DiPilato; Meghdad Rahdar; Yunzhao R. Ren; Curtis Chong; Jun O. Liu; Jin Zhang

2006-07-21T23:59:59.000Z

86

A high-throughput infrastructure for density functional theory calculations Anubhav Jain, Geoffroy Hautier, Charles J. Moore, Shyue Ping Ong, Christopher C. Fischer,  

E-Print Network (OSTI)

A high-throughput infrastructure for density functional theory calculations Anubhav Jain, Geoffroy-throughput computation Density functional theory Materials screening GGA Formation enthalpies a b s t r a c t The use of high-throughput density functional theory (DFT) calculations to screen for new materials and conduct

Ceder, Gerbrand

87

High-throughput data mined prediction of inorganic compounds and computational discovery of new lithium-ion battery cathode materials  

E-Print Network (OSTI)

The ability to computationally predict the properties of new materials, even prior to their synthesis, has been made possible due to the current accuracy of modern ab initio techniques. In some cases, high-throughput ...

Hautier, Geoffroy (Geoffroy T. F.)

2011-01-01T23:59:59.000Z

88

Advances in high-throughput speed, low-latency communication for embedded instrumentation ( 7th Annual SFAF Meeting, 2012)  

SciTech Connect

Scott Jordan on "Advances in high-throughput speed, low-latency communication for embedded instrumentation" at the 2012 Sequencing, Finishing, Analysis in the Future Meeting held June 5-7, 2012 in Santa Fe, New Mexico.

Jordan, Scott [Physik Instrumente] [Physik Instrumente

2012-06-01T23:59:59.000Z

89

Advances in high-throughput speed, low-latency communication for embedded instrumentation ( 7th Annual SFAF Meeting, 2012)  

ScienceCinema (OSTI)

Scott Jordan on "Advances in high-throughput speed, low-latency communication for embedded instrumentation" at the 2012 Sequencing, Finishing, Analysis in the Future Meeting held June 5-7, 2012 in Santa Fe, New Mexico.

Jordan, Scott [Physik Instrumente

2013-02-11T23:59:59.000Z

90

High Throughput Plasmid Sequencing with Illumina and CLC Bio (Seventh Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting 2012)  

ScienceCinema (OSTI)

Ajay Athavale (Monsanto) presents "High Throughput Plasmid Sequencing with Illumina and CLC Bio" at the 7th Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting held in June, 2012 in Santa Fe, NM.

Athavale, Ajay [Monsanto

2013-01-25T23:59:59.000Z

91

Nano-chemo-mechanical sensor array platform for high-throughput chemical analysis  

Science Journals Connector (OSTI)

We have developed a 2-D multiplexed cantilever array platform for high-throughput nanomechanical chemical sensing and analysis. After coating the cantilevers with alkane thiols having different functional end groups, we have performed vapor phase chemical sensing experiments with toluene and water vapor as targets. To overcome non-uniform responses caused by fabrication and imaging issues, the chemical response of each cantilever is self-calibrated using the thermal response of each cantilever. From these experiments, we could observe chemically induced nanoscale motion of cantilevers for various humidity or vapor concentration levels, and response differentiation with different functional end groups of thiols.

Si-Hyung Shawn Lim; Digvijay Raorane; Srinath Satyanarayana; Arunava Majumdar

2006-01-01T23:59:59.000Z

92

Getter sputtering system for high-throughput fabrication of composition spreads  

SciTech Connect

We describe a sputtering system that can deposit composition spreads in an effectively UHV environment but which does not require the high-throughput paradigm to be compromised by a long pump down each time a target is changed. The system deploys four magnetron sputter guns in a cryoshroud (getter sputtering) which allows elements such as Ti and Zr to be deposited with minimal contamination by oxygen or other reactive background gases. The system also relies on custom substrate heaters to give rapid heating and cool down. The effectiveness of the gettering technique is evaluated, and example results obtained for catalytic activity of a pseudoternary composition spread are presented.

Gregoire, John M.; Dover, R. B. van; Jin Jing; Di Salvo, Francis J.; Abruna, Hector D. [Department of Physics, Cornell University, Ithaca, New York 14853 (United States) and Cornell Fuel Cell Institute, Cornell University, Ithaca, New York 14853 (United States); Department of Materials Science and Engineering, Cornell University, Ithaca, New York 14853 (United States) and Cornell Fuel Cell Institute, Cornell University, Ithaca, New York 14853 (United States); Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853 (United States) and Cornell Fuel Cell Institute, Cornell University, Ithaca, New York 14853 (United States)

2007-07-15T23:59:59.000Z

93

VLPW: The Very Long Packet Window Architecture for High Throughput Network-On-Chip Router Designs  

E-Print Network (OSTI)

throughput. With the VLPW architecture, we propose two scheduling schemes: Global Fairness and Global Diversity. Our simulation results show that the VLPW router achieves more than 20% throughput improvement without negative effects on zero-load latency....

Gu, Haiyin

2012-10-19T23:59:59.000Z

94

High-throughput full-automatic synchrotron-based tomographic microscopy  

SciTech Connect

At the TOMCAT (TOmographic Microscopy and Coherent rAdiology experimenTs) beamline of the Swiss Light Source with an energy range of 8-45 keV and voxel size from 0.37 {micro}m to 7.4 {micro}m, full tomographic datasets are typically acquired in 5 to 10 min. To exploit the speed of the system and enable high-throughput studies to be performed in a fully automatic manner, a package of automation tools has been developed. The samples are automatically exchanged, aligned, moved to the correct region of interest, and scanned. This task is accomplished through the coordination of Python scripts, a robot-based sample-exchange system, sample positioning motors and a CCD camera. The tools are suited for any samples that can be mounted on a standard SEM stub, and require no specific environmental conditions. Up to 60 samples can be analyzed at a time without user intervention. The throughput of the system is dependent on resolution, energy and sample size, but rates of four samples per hour have been achieved with 0.74 {micro}m voxel size at 17.5 keV. The maximum intervention-free scanning time is theoretically unlimited, and in practice experiments have been running unattended as long as 53 h (the average beam time allocation at TOMCAT is 48 h per user). The system is the first fully automated high-throughput tomography station: mounting samples, finding regions of interest, scanning and reconstructing can be performed without user intervention. The system also includes many features which accelerate and simplify the process of tomographic microscopy.

Mader, Kevin; Marone, Federica; Hintermller, Christoph; Mikuljan, Gordan; Isenegger, Andreas; Stampanoni, Marco (SLS)

2011-08-16T23:59:59.000Z

95

Argonne's HigH THrougHpuT reseArcH LAborATory  

NLE Websites -- All DOE Office Websites (Extended Search)

accelerating materials innovation accelerating materials innovation Argonne's HigH THrougHpuT reseArcH LAborATory The conventional "one-at-a-time" sequential approach for synthesizing, characterizing and evaluating new materials typically provides only incremental improvements; it is both labor- and resource-intensive as well as very expensive. T h e d is c o v e r y a n d s y n t h e s is o f n e w m a t e r ia ls a r e c r it ic a l b o t t le n e c k s in t h e s e a r c h f o r a lt e r n a t iv e e n e r g y s o u r c e s . Argonne nATionAL LAborATory's High Throughput research Laboratory accelerates the discovery and optimization of new materials, leading to "quantum jump" improvements and fast-tracked marketplace entry. Argonne's HTR provides highly automated and parallel approaches to materials development. This allows scientists to

96

Generalized Schemes for High Throughput Manipulation of the Desulfovibrio vulgaris Hildenborough Genome.  

SciTech Connect

The ability to conduct advanced functional genomic studies of the thousands of 38 sequenced bacteria has been hampered by the lack of available tools for making high39 throughput chromosomal manipulations in a systematic manner that can be applied across 40 diverse species. In this work, we highlight the use of synthetic biological tools to 41 assemble custom suicide vectors with reusable and interchangeable DNA parts to 42 facilitate chromosomal modification at designated loci. These constructs enable an array 43 of downstream applications including gene replacement and creation of gene fusions with 44 affinity purification or localization tags. We employed this approach to engineer 45 chromosomal modifications in a bacterium that has previously proven difficult to 46 manipulate genetically, Desulfovibrio vulgaris Hildenborough, to generate a library of 47 662 strains. Furthermore, we demonstrate how these modifications can be used for 48 examining metabolic pathways, protein-protein interactions, and protein localization. The 49 ubiquity of suicide constructs in gene replacement throughout biology suggests that this 50 approach can be applied to engineer a broad range of species for a diverse array of 51 systems biological applications and is amenable to high-throughput implementation.

Chhabra, Swapnil [Lawrence Berkeley National Laboratory (LBNL); Butland, Gareth [Lawrence Berkeley National Laboratory (LBNL); Elias, Dwayne A [ORNL; Chandonia, John-Marc [Lawrence Berkeley National Laboratory (LBNL); Fok, Olivia [Lawrence Berkeley National Laboratory (LBNL); Juba, tom [University of Missouri; Gorur, A. [Lawrence Berkeley National Laboratory (LBNL); Allen, S. [University of California, San Francisco; Leung, C. M. [Lawrence Berkeley National Laboratory (LBNL); Keller, Kim [University of Missouri; Reveco, S. [Lawrence Berkeley National Laboratory (LBNL); Zane, Mr. Grant M. [University of Missouri, Columbia; Semkiw, Elizabeth M. [University of Missouri; Prathapam, R. [Lawrence Berkeley National Laboratory (LBNL); Gold, B. [Lawrence Berkeley National Laboratory (LBNL); Singer, Mary [Lawrence Berkeley National Laboratory (LBNL); Ouellet, M. [Lawrence Berkeley National Laboratory (LBNL); Sazakal, E. D. [University of California, San Francisco; Jorgens, Dominique [Lawrence Berkeley National Laboratory (LBNL); Price, Morgan N. [Lawrence Berkeley National Laboratory (LBNL); Witkowska, Ewa [University of California, San Francisco; Beller, Harry R. [Lawrence Berkeley National Laboratory (LBNL); Hazen, Terry [Lawrence Berkeley National Laboratory (LBNL); Biggin, Mark D. [Lawrence Berkeley National Laboratory (LBNL); Auer, Dr. Manfred [Lawrence Berkeley National Laboratory (LBNL); Wall, Judy D. [University of Missouri; Keasling, Jay [Lawrence Berkeley National Laboratory (LBNL)

2011-01-01T23:59:59.000Z

97

A high throughput platform for understanding the influence of excipients on physical and chemical stability  

Science Journals Connector (OSTI)

The present study puts forward a miniaturized high-throughput platform to understand influence of excipient selection and processing on the stability of a given drug compound. Four model drugs (sodium naproxen, theophylline, amlodipine besylate and nitrofurantoin) and ten different excipients were selected. Binary physical mixtures of drug and excipient were transferred to a 96-well plate followed by addition of water to simulate aqueous granulation environment. The plate was subjected for XRPD measurements followed by drying and subsequent XRPD and HPLC measurements of the dried samples. Excipients with different water sorbing potential were found to influence distinctly on the phase transformation behaviour of each drug. Moreover, the amount of water addition was also a critical factor affecting phase transformation behaviour. HPLC analysis revealed one of the drug:excipient pairs with a tendency for chemical degradation. The proposed high-throughput platform can be used during early drug development to simulate typical processing induced stress in a small scale and to understand possible phase transformation behaviour and influence of excipients on this.

Dhara Raijada; Claus Cornett; Jukka Rantanen

2013-01-01T23:59:59.000Z

98

High-Throughput Thin Film Approach for Screening of Temperature-Pressure-Composition Phase Space  

SciTech Connect

Many solar energy technologies, for example CIGS and CdTe photovoltaics, utilize materials in thin film form. The equilibrium phase diagrams for these and other more novel solar energy materials are not known or are irrelevant because of the non-equilibrium character of the thin film growth processes. We demonstrate a high-throughput thin film approach for screening of temperature-pressure-composition phase diagrams and phase spaces. The examples in focus are novel solar absorbers Cu-N, Cu-O and p-type transparent conductors in the Cr2O3-MnO system. The composition axis of the Cr2O3-MnO phase diagram was screened using a composition spread method. The temperature axis of the Mn-O phase diagram was screened using a temperature spread method. The pressure axes of the Cu-N and Cu-O phase diagrams were screened using rate spread method with the aid of non-equilibrium growth phenomena. Overall these three methods constitute an approach to high-throughput screening of inorganic thin film phase diagrams. This research is supported by U.S. Department of Energy as a part of two NextGen Sunshot projects and an Energy Frontier Research Center.

Zakutayev, A.; Subramaniyan, A.; Caskey, C. M.; Ndione, P. F.; Richards, R. M.; O'Hayre, R.; Ginley, D. S.

2013-01-01T23:59:59.000Z

99

High-throughput Accurate-wavelength Lens-based Visible Spectrometera  

SciTech Connect

A scanning visible spectrometer has been prototyped to complement fixed-wavelength transmission grating spectrometers for charge exchange recombination spectroscopy. Fast f/1.8 200 mm commercial lenses are used with a large 2160 mm-1 grating for high throughput. A stepping-motor controlled sine drive positions the grating, which is mounted on a precision rotary table. A high-resolution optical encoder on the grating stage allows the grating angle to be measured with an absolute accuracy of 0.075 arcsec, corresponding to a wavelength error ? 0.005 . At this precision, changes in grating groove density due to thermal expansion and variations in the refractive index of air are important. An automated calibration procedure determines all relevant spectrometer parameters to high accuracy. Changes in bulk grating temperature, atmospheric temperature and pressure are monitored between the time of calibration and the time of measurement to insure a persistent wavelength calibration

Ronald E. Belll and Filippo Scotti

2010-06-04T23:59:59.000Z

100

High-Throughput Pretreatment and Hydrolysis Systems for Screening Biomass Species in Aqueous Pretreatment of Plant Biomass  

NLE Websites -- All DOE Office Websites (Extended Search)

High-throughput High-throughput Pretreatment and Hydrolysis Systems for Screening Biomass Species in Aqueous Pretreatment of Plant Biomass Jaclyn D. DeMartini 1,2,3,Ã and Charles E. Wyman 1,2,3 1 Department of Chemical and Environmental Engineering, University of California, Riverside, USA 2 Center for Environmental Research and Technology, University of California, Riverside, USA 3 BioEnergy Science Center, Oak Ridge, USA 22.1 Introduction: The Need for High-throughput Technologies The primary barrier to low-cost biological conversion of lignocellulosic biomass to renewable fuels and chemicals is plant recalcitrance, that is to say, resistance of cell walls to deconstruction by enzymes or microbes [1,2]. However, the discovery and use of biomass species with reduced recalcitrance, when com- bined with optimized pretreatment processes and enzyme mixtures, could potentially

Note: This page contains sample records for the topic "integrated high throughput" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


101

A high-throughput method for assessing chemical toxicity using a Caenorhabditis elegans reproduction assay  

SciTech Connect

The National Research Council has outlined the need for non-mammalian toxicological models to test the potential health effects of a large number of chemicals while also reducing the use of traditional animal models. The nematode Caenorhabditis elegans is an attractive alternative model because of its well-characterized and evolutionarily conserved biology, low cost, and ability to be used in high-throughput screening. A high-throughput method is described for quantifying the reproductive capacity of C. elegans exposed to chemicals for 48 h from the last larval stage (L4) to adulthood using a COPAS Biosort. Initially, the effects of exposure conditions that could influence reproduction were defined. Concentrations of DMSO vehicle {<=} 1% did not affect reproduction. Previous studies indicated that C. elegans may be influenced by exposure to low pH conditions. At pHs greater than 4.5, C. elegans reproduction was not affected; however below this pH there was a significant decrease in the number of offspring. Cadmium chloride was chosen as a model toxicant to verify that automated measurements were comparable to those of traditional observational studies. EC{sub 50} values for cadmium for automated measurements (176-192 {mu}M) were comparable to those previously reported for a 72-h exposure using manual counting (151 {mu}M). The toxicity of seven test toxicants on C. elegans reproduction was highly correlative with rodent lethality suggesting that this assay may be useful in predicting the potential toxicity of chemicals in other organisms.

Boyd, Windy A. [Biomolecular Screening Branch, National Toxicology Program, Research Triangle Park, NC 27709 (United States); McBride, Sandra J.; Rice, Julie R.; Snyder, Daniel W. [Biomolecular Screening Branch, National Toxicology Program, Research Triangle Park, NC 27709 (United States); Freedman, Jonathan H., E-mail: freedma1@niehs.nih.go [Biomolecular Screening Branch, National Toxicology Program, Research Triangle Park, NC 27709 (United States); Laboratory of Toxicology and Pharmacology, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC 27709 (United States)

2010-06-01T23:59:59.000Z

102

HIGH INTEGRITY MAGNESIUM AUTOMOTIVE COMPONENTS (HIMAC) | Department...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

HIGH INTEGRITY MAGNESIUM AUTOMOTIVE COMPONENTS (HIMAC) HIGH INTEGRITY MAGNESIUM AUTOMOTIVE COMPONENTS (HIMAC) 2009 DOE Hydrogen Program and Vehicle Technologies Program Annual...

103

Test bed for a high throughput supersonic chemical oxygen - iodine laser  

SciTech Connect

The paper reports the development of a test bed for a chemical oxygen - iodine laser based on a high throughput jet flow singlet oxygen generator (JSOG). The system provides vertical singlet oxygen extraction followed by horizontal orientation of subsequent subsystems. This design enables the study of flow complexities and engineering aspects of a distributed weight system as an input for mobile and other platform-mounted systems developed for large scale power levels. The system under consideration is modular and consists of twin SOGs, plenum and supersonic nozzle modules, with the active medium produced in the laser cavity. The maximal chlorine flow rate for the laser is {approx}1.5 mole s{sup -1} achieving a typical chemical efficiency of about 18%. (lasers)

Singhal, Gaurav; Mainuddin; Rajesh, R; Varshney, A K; Dohare, R K; Kumar, Sanjeev; Singh, V K; Kumar, Ashwani; Verma, Avinash C; Arora, B S; Chaturvedi, M K; Tyagi, R K; Dawar, A L

2011-05-31T23:59:59.000Z

104

Nanoelectrospray ion generation for high-throughput mass spectrometry using a micromachined ultrasonic ejector array  

SciTech Connect

Ultrasonic electrospray ionization (ESI) for high-throughput mass spectrometry is demonstrated using a silicon micromachined microarray. The device uses a micromachined ultrasonic atomizer operating in the 900 kHz-2.5 MHz range for droplet generation and a metal electrode in the fluid cavity for ionization. Since the atomization and ionization processes are separated, the ultrasonic ESI source shows the potential for operation at low voltages with a wide range of solvents in contrast with conventional capillary ESI technology. This is demonstrated using the ultrasonic ESI microarray to obtain the mass spectrum of a 10 {mu}M reserpine sample on a time of flight mass spectrometer with 197:1 signal-to-noise ratio at an ionization potential of 200 V.

Aderogba, S.; Meacham, J.M.; Degertekin, F.L.; Fedorov, A.G.; Fernandez, F.M. [G.W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332 (United States); School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332 (United States)

2005-05-16T23:59:59.000Z

105

A High-Throughput 3-D X-ray Microtomography System with Real-Time 3-D  

NLE Websites -- All DOE Office Websites (Extended Search)

Throughput 3-D X-ray Microtomography System with Real-Time 3-D Throughput 3-D X-ray Microtomography System with Real-Time 3-D Reconstruction A high-throughput x-ray microtomography system (XMS) that can acquire, reconstruct, and interactively display rendered 3-D images of a sample at micrometer-scale resolution within minutes has been developed at Advanced Photon Source (APS) beamline 2-BM, which is managed by the Synchrotron Radiation Instrumentation Collaborative Access Team (SRI-CAT). This system could bring better understanding of an array of scientific and technological problems, ranging from failure in microelectronic devices to structures in biological samples. A rendered image from a three-dimensional tomographic reconstruction of a cricket, obtained with the x-ray microtomography system. The image has been digitally cut at different planes to show the internal structures of the cricket's head.

106

PIPELINED PARALLEL ARCHITECTURE FOR HIGH THROUGHPUT MAP DETECTORS Ruwan Ratnayake, Gu-Yeon Wei and Aleksandar Kavcic  

E-Print Network (OSTI)

PIPELINED PARALLEL ARCHITECTURE FOR HIGH THROUGHPUT MAP DETECTORS Ruwan Ratnayake, Gu-Yeon Wei performance close to the channel capacity limits. Deep pipelined architecture for the forward only method, where as FB-BCJR only allow sequential state metric computations. Parallelism facilitates pipelining, re

Kavcic, Aleksandar

107

On-the-fly machine-learning for high-throughput experiments: search for rare-earth-free permanent magnets  

SciTech Connect

Advanced materials characterization techniques with ever-growing data acquisition speed and storage capabilities represent a challenge in modern materials science, and new procedures to quickly assess and analyze the data are needed. Machine learning approaches are effective in reducing the complexity of data and rapidly homing in on the underlying trend in multi-dimensional data. Here, we show that by employing an algorithm called the mean shift theory to a large amount of diffraction data in high-throughput experimentation, one can streamline the process of delineating the structural evolution across compositional variations mapped on combinatorial libraries with minimal computational cost. Data collected at a synchrotron beamline are analyzed on the fly, and by integrating experimental data with the inorganic crystal structure database (ICSD), we can substantially enhance the accuracy in classifying the structural phases across ternary phase spaces. We have used this approach to identify a novel magnetic phase with enhanced magnetic anisotropy which is a candidate for rare-earth free permanent magnet.

Kusne, Aaron Gilad [University of Maryland; Gao, Tieren [University of Maryland; Mehta, Apurva [SLAC National Accelerator Laboratory; Ke, Liqin [Ames Laboratory; Nguyen, Manh Cuong [Ames Laboratory; Ho, Kai-Ming [Ames Laboratory; Antropov, Vladimir [Ames Laboratory; Wang, Cai-Zhuang [Ames Laboratory; Kramer, Matthew J [Ames Laboratory; Long, Christian [University of Maryland; Takeuchi, Ichiro [University of Maryland

2014-09-15T23:59:59.000Z

108

Metal Organic Framework Research: High Throughput Discovery of Robust Metal Organic Framework for CO2 Capture  

SciTech Connect

IMPACCT Project: LBNL is developing a method for identifying the best metal organic frameworks for use in capturing CO2 from the flue gas of coal-fired power plants. Metal organic frameworks are porous, crystalline compounds that, based on their chemical structure, vary considerably in terms of their capacity to grab hold of passing CO2 molecules and their ability to withstand the harsh conditions found in the gas exhaust of coal-fired power plants. Owing primarily to their high tunability, metal organic frameworks can have an incredibly wide range of different chemical and physical properties, so identifying the best to use for CO2 capture and storage can be a difficult task. LBNL uses high-throughput instrumentation to analyze nearly 100 materials at a time, screening them for the characteristics that optimize their ability to selectively adsorb CO2 from coal exhaust. Their work will identify the most promising frameworks and accelerate their large-scale commercial development to benefit further research into reducing the cost of CO2 capture and storage.

None

2010-08-01T23:59:59.000Z

109

Evaluation of a New Remote Handling Design for High Throughput Annular Centrifugal Contactors  

SciTech Connect

Advanced designs of nuclear fuel recycling plants are expected to include more ambitious goals for aqueous based separations including; higher separations efficiency, high-level waste minimization, and a greater focus on continuous processes to minimize cost and footprint. Therefore, Annular Centrifugal Contactors (ACCs) are destined to play a more important role for such future processing schemes. Previous efforts defined and characterized the performance of commercial 5 cm and 12.5 cm single-stage ACCs in a cold environment. The next logical step, the design and evaluation of remote capable pilot scale ACCs in a hot or radioactive environment was reported earlier. This report includes the development of remote designs for ACCs that can process the large throughput rates needed in future nuclear fuel recycling plants. Novel designs were developed for the remote interconnection of contactor units, clean-in-place and drain connections, and a new solids removal collection chamber. A three stage, 12.5 cm diameter rotor module has been constructed and evaluated for operational function and remote handling in highly radioactive environments. This design is scalable to commercial CINC ACC models from V-05 to V-20 with total throughput rates ranging from 20 to 650 liters per minute. The V-05R three stage prototype was manufactured by the commercial vendor for ACCs in the U.S., CINC mfg. It employs three standard V-05 clean-in-place (CIP) units modified for remote service and replacement via new methods of connection for solution inlets, outlets, drain and CIP. Hydraulic testing and functional checks were successfully conducted and then the prototype was evaluated for remote handling and maintenance suitability. Removal and replacement of the center position V-05R ACC unit in the three stage prototype was demonstrated using an overhead rail mounted PaR manipulator. This evaluation confirmed the efficacy of this innovative design for interconnecting and cleaning individual stages while retaining the benefits of commercially reliable ACC equipment for remote applications in the nuclear industry. Minor modifications and suggestions for improved manual remote servicing by the remote handling specialists were provided but successful removal and replacement was demonstrated in the first prototype.

David H. Meikrantz; Troy G. Garn; Jack D. Law; Lawrence L. Macaluso

2009-09-01T23:59:59.000Z

110

High Throughput Software for Powder Diffraction and its Application to Heterogeneous Catalysis  

E-Print Network (OSTI)

In this thesis we investigate high throughput computational methods for processing large quantities of data collected from synchrotrons and their application to spectral analysis of powder diffraction data. We also present the main product of this PhD programme, specifically a software called 'EasyDD' developed by the author. This software was created to meet the increasing demand on data processing and analysis capabilities as required by modern detectors which produce huge quantities of data. Modern detectors coupled with the high intensity X-ray sources available at synchrotrons have led to the situation where datasets can be collected in ever shorter time scales and in ever larger numbers. Such large volumes of datasets pose a data processing bottleneck which augments with current and future instrument development. EasyDD has achieved its objectives and made significant contributions to scientific research. It can also be used as a model for more mature attempts in the future. EasyDD is currently in use by a number of researchers in a number of academic and research institutions to process high-energy diffraction data. These include data collected by different techniques such as Energy Dispersive Diffraction, Angle Dispersive Diffraction and Computer Aided Tomography. EasyDD has already been used in a number of published studies, and is currently in use by the High Energy X-Ray Imaging Technology project. The software was also used by the author to process and analyse datasets collected from synchrotron radiation facilities. In this regard, the thesis presents novel scientific research involving the use of EasyDD to handle large diffraction datasets in the study of alumina-supported metal oxide catalyst bodies. These data were collected using Tomographic Energy Dispersive Diffraction Imaging and Computer Aided Tomography techniques.

Taha Sochi

2010-12-20T23:59:59.000Z

111

PHYSICAL REVIEW B 84, 014103 (2011) Screening for high-performance piezoelectrics using high-throughput density functional theory  

E-Print Network (OSTI)

-throughput density functional theory Rickard Armiento,1 Boris Kozinsky,2 Marco Fornari,3 and Gerbrand Ceder1 1-scale density functional theory (DFT) investigation of the ABO3 chemical space in the perovskite crystal-throughput density functional theory19,20 calculations. The last decades have seen a rapid increase of computational

Ceder, Gerbrand

112

Laser-Induced Fluorescence Detection in High-Throughput Screening of Heterogeneous Catalysts and Single Cells Analysis  

SciTech Connect

Laser-induced fluorescence detection is one of the most sensitive detection techniques and it has found enormous applications in various areas. The purpose of this research was to develop detection approaches based on laser-induced fluorescence detection in two different areas, heterogeneous catalysts screening and single cell study. First, we introduced laser-induced imaging (LIFI) as a high-throughput screening technique for heterogeneous catalysts to explore the use of this high-throughput screening technique in discovery and study of various heterogeneous catalyst systems. This scheme is based on the fact that the creation or the destruction of chemical bonds alters the fluorescence properties of suitably designed molecules. By irradiating the region immediately above the catalytic surface with a laser, the fluorescence intensity of a selected product or reactant can be imaged by a charge-coupled device (CCD) camera to follow the catalytic activity as a function of time and space. By screening the catalytic activity of vanadium pentoxide catalysts in oxidation of naphthalene, we demonstrated LIFI has good detection performance and the spatial and temporal resolution needed for high-throughput screening of heterogeneous catalysts. The sample packing density can reach up to 250 x 250 subunits/cm{sub 2} for 40-{micro}m wells. This experimental set-up also can screen solid catalysts via near infrared thermography detection.

Hui Su

2001-05-01T23:59:59.000Z

113

A review of the theory, methods and recent applications of high-throughput single-cell droplet microfluidics  

Science Journals Connector (OSTI)

Most cell biology experiments are performed in bulk cell suspensions where cell secretions become diluted and mixed in a contiguous sample. Confinement of single cells to small, picoliter-sized droplets within a continuous phase of oil provides chemical isolation of each cell, creating individual microreactors where rare cell qualities are highlighted and otherwise undetectable signals can be concentrated to measurable levels. Recent work in microfluidics has yielded methods for the encapsulation of cells in aqueous droplets and hydrogels at kilohertz rates, creating the potential for millions of parallel single-cell experiments. However, commercial applications of high-throughput microdroplet generation and downstream sensing and actuation methods are still emerging for cells. Using fluorescence-activated cell sorting (FACS) as a benchmark for commercially available high-throughput screening, this focused review discusses the fluid physics of droplet formation, methods for cell encapsulation in liquids and hydrogels, sensors and actuators and notable biological applications of high-throughput single-cell droplet microfluidics.

Todd P Lagus; Jon F Edd

2013-01-01T23:59:59.000Z

114

New Challenges of the Computation of Multiple Sequence Alignments in the High-Throughput Era (2010 JGI/ANL HPC Workshop)  

ScienceCinema (OSTI)

Cedric Notredame from the Centre for Genomic Regulation gives a presentation on "New Challenges of the Computation of Multiple Sequence Alignments in the High-Throughput Era" at the JGI/Argonne HPC Workshop on January 26, 2010.

Notredame, Cedric [Centre for Genomic Regulation

2011-06-08T23:59:59.000Z

115

High density Integrated Optoelectronic Circuits for High Speed Photonic Microsystems  

E-Print Network (OSTI)

High density Integrated Optoelectronic Circuits for High Speed Photonic Microsystems K. Minoglou.minoglou@imel.demorkitos.gr Abstract. The study of high density integrated optoelectronic circuits involves the development of hybrid integration technologies and the generation of models for the optoelectronic devices. To meet these goals

Kouroupetroglou, Georgios

116

Laser-Induced Fluorescence Detection in High-Throughput Screening of Heterogeneous Catalysts and Single Cells Analysis  

SciTech Connect

Laser-induced fluorescence detection is one of the most sensitive detection techniques and it has found enormous applications in various areas. The purpose of this research was to develop detection approaches based on laser-induced fluorescence detection in two different areas, heterogeneous catalysts screening and single cell study. First, the author introduced laser-induced imaging (LIFI) as a high-throughput screening technique for heterogeneous catalysts to explore the use of this high-throughput screening technique in discovery and study of various heterogeneous catalyst systems. This scheme is based on the fact that the creation or the destruction of chemical bonds alters the fluorescence properties of suitably designed molecules. By irradiating the region immediately above the catalytic surface with a laser, the fluorescence intensity of a selected product or reactant can be imaged by a charge-coupled device (CCD) camera to follow the catalytic activity as a function of time and space. By screening the catalytic activity of vanadium pentoxide catalysts in oxidation of naphthalene, they demonstrated LIFI has good detection performance and the spatial and temporal resolution needed for high-throughput screening of heterogeneous catalysts. The sample packing density can reach up to 250 x 250 subunits/cm{sup 2} for 40-{micro}m wells. This experimental set-up also can screen solid catalysts via near infrared thermography detection. In the second part of this dissertation, the author used laser-induced native fluorescence coupled with capillary electrophoresis (LINF-CE) and microscope imaging to study the single cell degranulation. On the basis of good temporal correlation with events observed through an optical microscope, they have identified individual peaks in the fluorescence electropherograms as serotonin released from the granular core on contact with the surrounding fluid.

Hui Su

2001-05-25T23:59:59.000Z

117

High-throughput manufacturing of size-tuned liposomes by a new microfluidics method using enhanced statistical tools for characterization  

Science Journals Connector (OSTI)

Abstract Microfluidics has recently emerged as a new method of manufacturing liposomes, which allows for reproducible mixing in miliseconds on the nanoliter scale. Here we investigate microfluidics-based manufacturing of liposomes. The aim of these studies was to assess the parameters in a microfluidic process by varying the total flow rate (TFR) and the flow rate ratio (FRR) of the solvent and aqueous phases. Design of experiment and multivariate data analysis were used for increased process understanding and development of predictive and correlative models. High FRR lead to the bottom-up synthesis of liposomes, with a strong correlation with vesicle size, demonstrating the ability to in-process control liposomes size; the resulting liposome size correlated with the FRR in the microfluidics process, with liposomes of 50nm being reproducibly manufactured. Furthermore, we demonstrate the potential of a high throughput manufacturing of liposomes using microfluidics with a four-fold increase in the volumetric flow rate, maintaining liposome characteristics. The efficacy of these liposomes was demonstrated in transfection studies and was modelled using predictive modeling. Mathematical modelling identified FRR as the key variable in the microfluidic process, with the highest impact on liposome size, polydispersity and transfection efficiency. This study demonstrates microfluidics as a robust and high-throughput method for the scalable and highly reproducible manufacture of size-controlled liposomes. Furthermore, the application of statistically based process control increases understanding and allows for the generation of a design-space for controlled particle characteristics.

Elisabeth Kastner; Randip Kaur; Deborah Lowry; Behfar Moghaddam; Alexander Wilkinson; Yvonne Perrie

2014-01-01T23:59:59.000Z

118

A comprehensive insight into bacterial virulence in drinking water using 454 pyrosequencing and Illumina high-throughput sequencing  

Science Journals Connector (OSTI)

Abstract In order to comprehensively investigate bacterial virulence in drinking water, 454 pyrosequencing and Illumina high-throughput sequencing were used to detect potential pathogenic bacteria and virulence factors (VFs) in a full-scale drinking water treatment and distribution system. 16S rRNA gene pyrosequencing revealed high bacterial diversity in the drinking water (441586 operational taxonomic units). Bacterial diversity decreased after chlorine disinfection, but increased after pipeline distribution. ?-Proteobacteria was the most dominant taxonomic class. Alignment against the established pathogen database showed that several types of putative pathogens were present in the drinking water and Pseudomonas aeruginosa had the highest abundance (over 11 of total sequencing reads). Many pathogens disappeared after chlorine disinfection, but P. aeruginosa and Leptospira interrogans were still detected in the tap water. High-throughput sequencing revealed prevalence of various pathogenicity islands and virulence proteins in the drinking water, and translocases, transposons, Clp proteases and flagellar motor switch proteins were the predominant VFs. Both diversity and abundance of the detectable \\{VFs\\} increased after the chlorination, and decreased after the pipeline distribution. This study indicates that joint use of 454 pyrosequencing and Illumina sequencing can comprehensively characterize environmental pathogenesis, and several types of putative pathogens and various \\{VFs\\} are prevalent in drinking water.

Kailong Huang; Xu-Xiang Zhang; Peng Shi; Bing Wu; Hongqiang Ren

2014-01-01T23:59:59.000Z

119

RECENT PROCESS AND EQUIPMENT IMPROVEMENTS TO INCREASE HIGH LEVEL WASTE THROUGHPUT AT THE DEFENSE WASTE PROCESSING FACILITY  

SciTech Connect

The Savannah River Site's (SRS) Defense Waste Processing Facility (DWPF) began stabilizing high level waste (HLW) in a glass matrix in 1996. Over the past few years, there have been several process and equipment improvements at the DWPF to increase the rate at which the high level waste can be stabilized. These improvements have either directly increased waste processing rates or have desensitized the process to upsets, thereby minimizing downtime and increasing production. Improvements due to optimization of waste throughput with increased HLW loading of the glass resulted in a 6% waste throughput increase based upon operational efficiencies. Improvements in canister production include the pour spout heated bellows liner (5%), glass surge (siphon) protection software (2%), melter feed pump software logic change to prevent spurious interlocks of the feed pump with subsequent dilution of feed stock (2%) and optimization of the steam atomized scrubber (SAS) operation to minimize downtime (3%) for a total increase in canister production of 12%. A number of process recovery efforts have allowed continued operation. These include the off gas system pluggage and restoration, slurry mix evaporator (SME) tank repair and replacement, remote cleaning of melter top head center nozzle, remote melter internal inspection, SAS pump J-Tube recovery, inadvertent pour scenario resolutions, dome heater transformer bus bar cooling water leak repair and new Infra-red camera for determination of glass height in the canister are discussed.

Odriscoll, R; Allan Barnes, A; Jim Coleman, J; Timothy Glover, T; Robert Hopkins, R; Dan Iverson, D; Jeff Leita, J

2008-01-15T23:59:59.000Z

120

High Throughput Combinatorial Screening of Biometic Metal-Organic Materials for Military Hydrogen-Storage Materials (New Joint Miami U/NREL DoD/DLA Project) (presentation)  

NLE Websites -- All DOE Office Websites (Extended Search)

Miami University/NREL DoD/DLA Project Miami University/NREL DoD/DLA Project High throughput combinatorial screening of biomimetic metal-organic materials for military hydrogen-storage applications Philip Parilla - NREL Joe Zhou, Dan Zhao - Miami U, Ohio Jeff Blackburn, Kevin O'Neill, Lin Simpson, Mike Heben - NREL Outline * Miami/NREL Project - Synthesis (Miami) - High Throughput Characterization (NREL) - Other Characterization * Other High Throughput Activities (NREL) - Parallel Sieverts - Parallel Gravimetric * Final Comments Overview of Miami/NREL Project * Goals - Development of H 2 storage materials based on MOFs, targeting 15 kJ/mole binding energy and high density of H 2 sites - Development of optical-based detection of adsorbed H 2 allowing rapid screening of samples * Approach - Combinatorial MOFs synthesis involving 8

Note: This page contains sample records for the topic "integrated high throughput" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


121

A WiMAX/LTE Compliant FPGA Implementation of a High-Throughput Low-Complexity 4x4 64-QAM Soft MIMO Receiver  

E-Print Network (OSTI)

of antennas and constellation order. Therefore, it is suitable for LTE-Advanced and IEEE 802.16m broadband must be scalable as the number of antennas and the constellation order increase in order to meet high, an appropriate VLSI archi- tecture is required to yield high-throughput, energy- efficient implementation

Gulak, P. Glenn

122

Engineering of a high-throughput screening system to identify cellulosic biomass, pretreatments, and enzyme formulations that enhance sugar release  

NLE Websites -- All DOE Office Websites (Extended Search)

Engineering Engineering of a High-Throughput Screening System to Identify Cellulosic Biomass, Pretreatments, and Enzyme Formulations That Enhance Sugar Release Michael H. Studer, Jaclyn D. DeMartini, Simone Brethauer, Heather L. McKenzie, Charles E. Wyman Chemical and Environmental Engineering Department, Center for Environmental Research and Technology, Bourns College of Engineering, University of California Riverside, 1084 Columbia Avenue, Riverside, California 92507; telephone: þ951-781-5791; fax: þ951-781-5790; e-mail: charles.wyman@ucr.edu Received 7 April 2009; revision received 21 August 2009; accepted 31 August 2009 Published online 3 September 2009 in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/bit.22527 ABSTRACT: The recalcitrance of cellulosic biomass, the only abundant, sustainable feedstock for making liquid fuels, is a primary

123

High-throughput identification of off-targets for the mechanistic study of severe adverse drug reactions induced by analgesics  

SciTech Connect

Drugs may induce adverse drug reactions (ADRs) when they unexpectedly bind to proteins other than their therapeutic targets. Identification of these undesired protein binding partners, called off-targets, can facilitate toxicity assessment in the early stages of drug development. In this study, a computational framework was introduced for the exploration of idiosyncratic mechanisms underlying analgesic-induced severe adverse drug reactions (SADRs). The putative analgesic-target interactions were predicted by performing reverse docking of analgesics or their active metabolites against human/mammal protein structures in a high-throughput manner. Subsequently, bioinformatics analyses were undertaken to identify ADR-associated proteins (ADRAPs) and pathways. Using the pathways and ADRAPs that this analysis identified, the mechanisms of SADRs such as cardiac disorders were explored. For instance, 53 putative ADRAPs and 24 pathways were linked with cardiac disorders, of which 10 ADRAPs were confirmed by previous experiments. Moreover, it was inferred that pathways such as base excision repair, glycolysis/glyconeogenesis, ErbB signaling, calcium signaling, and phosphatidyl inositol signaling likely play pivotal roles in drug-induced cardiac disorders. In conclusion, our framework offers an opportunity to globally understand SADRs at the molecular level, which has been difficult to realize through experiments. It also provides some valuable clues for drug repurposing. - Highlights: A novel computational framework was developed for mechanistic study of SADRs. Off-targets of drugs were identified in large scale and in a high-throughput manner. SADRs like cardiac disorders were systematically explored in molecular networks. A number of ADR-associated proteins were identified.

Pan, Jian-Bo [Department of Chemical Biology, College of Chemistry and Chemical Engineering, The Key Laboratory for Chemical Biology of Fujian Province, Xiamen University, Xiamen, Fujian 361005 (China); Ji, Nan; Pan, Wen; Hong, Ru [State Key Laboratory of Stress Cell Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian 361102 (China); Wang, Hao [Department of Chemical Biology, College of Chemistry and Chemical Engineering, The Key Laboratory for Chemical Biology of Fujian Province, Xiamen University, Xiamen, Fujian 361005 (China); Ji, Zhi-Liang, E-mail: appo@xmu.edu.cn [State Key Laboratory of Stress Cell Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian 361102 (China); Department of Chemical Biology, College of Chemistry and Chemical Engineering, The Key Laboratory for Chemical Biology of Fujian Province, Xiamen University, Xiamen, Fujian 361005 (China)

2014-01-01T23:59:59.000Z

124

NSF ITR Project ABSTRACTION HIERARCHY MODELING OF HIGH-THROUGHPUT SCREENING  

E-Print Network (OSTI)

that are also integrated in the HTS line), this equipment has no proprietary control #12;software. The labeling/configuration" dialogs presented through an assay method programming application/interface used to control the entire AUTOMATION David B.Kaber & Steffen Junginger Overview: This document presents abstraction hierarchy (AH

Kaber, David B.

125

Asynchronous Progression through the Lytic Cascade and Variations in Intracellular Viral Loads Revealed by High-Throughput Single-Cell Analysis of Kaposi's Sarcoma-Associated Herpesvirus Infection  

Science Journals Connector (OSTI)

...microscopy with the statistical power of high-throughput traditional...cytometry. We collected data on infected HeLa cells...assess intracellular viral load in individual cells...12, 20, 21). Our data indicate that the automated...correlates with the viral load in individual cells...

Laura A. Adang; Christopher H. Parsons; Dean H. Kedes

2006-10-15T23:59:59.000Z

126

High-Throughput Hacking of the Methylation Patterns in Breast Cancer by In vitro Transcription and Thymidine-Specific Cleavage Mass Array on MALDI-TOF Silico-Chip  

Science Journals Connector (OSTI)

...Research Article Cancer Genes and Genomics High-Throughput Hacking of the Methylation Patterns in Breast Cancer by In vitro Transcription...Supplement: Supplementary Data Supplementary Data High-throughput hacking of the methylation patterns in breast cancer by in vitro transcription...

Ramin Radpour; Mahdi Montazer Haghighi; Alex Xiu-Cheng Fan; Peyman Mohammadi Torbati; Sinuhe Hahn; Wolfgang Holzgreve; Xiao Yan Zhong

2008-11-01T23:59:59.000Z

127

Development of High-Capacity Cathode Materials with Integrated...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Development of High-Capacity Cathode Materials with Integrated Structures Development of High-Capacity Cathode Materials with Integrated Structures 2013 DOE Hydrogen and Fuel Cells...

128

Development of high-capacity cathode materials with integrated...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Development of high-capacity cathode materials with integrated structures Development of high-capacity cathode materials with integrated structures 2009 DOE Hydrogen Program and...

129

Low-damage high-throughput grazing-angle sputter deposition on graphene  

SciTech Connect

Despite the prevalence of sputter deposition in the microelectronics industry, it has seen very limited applications for graphene electronics. In this letter, we report systematic investigation of the sputtering induced damages in graphene and identify the energetic sputtering gas neutrals as the primary cause of graphene disorder. We further demonstrate a grazing-incidence sputtering configuration that strongly suppresses fast neutral bombardment and retains graphene structure integrity, creating considerably lower damage than electron-beam evaporation. Such sputtering technique yields fully covered, smooth thin dielectric films, highlighting its potential for contact metals, gate oxides, and tunnel barriers fabrication in graphene device applications.

Chen, C.-T.; Gajek, M.; Raoux, S. [IBM Thomas J. Watson Research Center, Yorktown Heights, New York 10598 (United States); Casu, E. A. [IBM Thomas J. Watson Research Center, Yorktown Heights, New York 10598 (United States); Politecnico di Torino, Turin 10129 (Italy)

2013-07-15T23:59:59.000Z

130

Development of a high-throughput fermentation assay using colorimetric measurement of gas production.  

E-Print Network (OSTI)

??Typical methods for determining ethanol production from biomass feedstocks involve the use of High Performance Liquid Chromatography (HPLC) or Gas Chromatography (GC). Such methods require (more)

Bly, Steven

2008-01-01T23:59:59.000Z

131

Technology assessment and feasibility study of high-throughput single cell force spectroscopy  

E-Print Network (OSTI)

In the last decade, the field of single cell mechanics has emerged with the development of high resolution experimental and computational methods, providing significant amount of information about individual cells instead ...

Cheng, He, M. Eng. Massachusetts Institute of Technology

2010-01-01T23:59:59.000Z

132

Dynamic analysis of MAPK signaling using a high-throughput microfluidic single-cell imaging platform  

Science Journals Connector (OSTI)

...steps are used to realize monolithic multilayer devices. Photolithography masks were designed by using AutoCAD software (Autodesk) and used to generate high-resolution (20,000 dpi) transparency masks (CAD/Art Services). Molds were fabricated...

R. J. Taylor; D. Falconnet; A. Niemist; S. A. Ramsey; S. Prinz; I. Shmulevich; T. Galitski; C. L. Hansen

2009-01-01T23:59:59.000Z

133

Application of High Throughput Pretreatment and Co-Hydrolysis System to Thermochemical  

E-Print Network (OSTI)

and enzymatic hydrolysis conditions. Although hydrothermal pretreatment is currently being employed in most high were compared to results from hydrothermal pretreatments, providing new insights in understanding their recalcitrance and consolidating processing of enzymes and microorganisms to overcome biomass recalci- trance

California at Riverside, University of

134

High Efficiency Solar Integrated Roof Membrane Product  

SciTech Connect

This project was designed to address the Solar Energy Technology Program objective, to develop new methods to integrate photovoltaic (PV) cells or modules within a building-integrated photovoltaic (BIPV) application that will result in lower installed cost as well as higher efficiencies of the encapsulated/embedded PV module. The technology assessment and development focused on the evaluation and identification of manufacturing technologies and equipment capable of producing such low-cost, high-efficiency, flexible BIPV solar cells on single-ply roofing membranes.

Partyka, Eric; Shenoy, Anil

2013-05-15T23:59:59.000Z

135

Development of a multiplexed microbioreactor system for high-throughput bioprocessing  

E-Print Network (OSTI)

. However, this is a challenge with current bioreactor technology. The high cost and labor required and fluidic connectors, their sterilization, and disassembly and cleaning. While some fermentation parameters), for example, operates six reactors in parallel, and the ``Fedbatch-Pro'' (DASGIP AG, Germany) includes up

Sinskey, Anthony J.

136

Interfacing Capillary Electrophoresis and 2D-Infrared Spectroscopy for High Throughput Proteomics  

E-Print Network (OSTI)

and parameters defining the wettability of the substrate plate such as buffer conductivity, applied electric efficiency, the sample therefore needs to be concentrated onto an area while a linear motor stage is translating the substrate plate beneath. A high analyte area Optical

Rosso, Lula

137

Air-stable ink for scalable, high-throughput layer deposition  

DOE Patents (OSTI)

A method for producing and depositing air-stable, easily decomposable, vulcanized ink on any of a wide range of substrates is disclosed. The ink enables high-volume production of optoelectronic and/or electronic devices using scalable production methods, such as roll-to-roll transfer, fast rolling processes, and the like.

Weil, Benjamin D; Connor, Stephen T; Cui, Yi

2014-02-11T23:59:59.000Z

138

Applications of high throughput (combinatorial) methodologies to electronic, magnetic, optical, and energy-related materials  

E-Print Network (OSTI)

materials science for electronic, magnetic, optical, and energy-related materials. It is expected that high, and energy-related materials Martin L. Green, Ichiro Takeuchi, and Jason R. Hattrick-Simpers Citation: J) methodologies to electronic, magnetic, optical, and energy-related materials Martin L. Green,1 Ichiro Takeuchi,2

Rubloff, Gary W.

139

Droplet-based microfluidics for high-throughput screening of a metagenomic library for isolation of microbial enzymes  

Science Journals Connector (OSTI)

Abstract This paper proposes a high-throughput, function-based screening approach of a metagenomic library for isolating novel microbial enzymes by droplet-based microfluidics. We used gel microdroplets (GMDs) dispersed in oil as picoliter-volume reaction vessels for lipolytic enzyme by encapsulating cells in individual GMDs. Using this approach, we monitored the growth of individual cells encapsulated in \\{GMDs\\} and assessed the enzyme reaction activities at the level of an individual GMD. We then applied this method to screen lipolytic enzyme genes from the metagenomic library constructed from soil collected from a quercus serrate forest of Mount Tsukuba, Ibaraki, Japan. In the workflow presented in this study, metagenomic library clones were encapsulated in 100-pL \\{GMDs\\} with a fluorogenic reporter substrate. A total of 67,000 metagenomic library clones can be screened in only 24h with reduced consumption of reagents (i.e., microfluidic \\{GMDs\\} as an efficient tool for metagenomic library screening of industrially relevant enzymes with the potential of significantly reducing the cost and time factors involved in successful practical application of microbial enzymes.

Masahito Hosokawa; Yuri Hoshino; Yohei Nishikawa; Tomotada Hirose; Dong Hyun Yoon; Tetsushi Mori; Tetsushi Sekiguchi; Shuichi Shoji; Haruko Takeyama

2014-01-01T23:59:59.000Z

140

Automation of High?Throughput Crystal Screening and Data Collection at SSRL  

Science Journals Connector (OSTI)

A robotic system for auto?mounting crystals from liquid nitrogen is now operational on SSRL beamlines (Cohen et al. J. Appl. Cryst. (2002). 35 720726). The system uses a small industrial 4?axis robot with a custom built actuator. Once mounted automated alignment of the sample loop to the X?ray beam readies the crystal for data collection. After data collection samples are returned to the cassette. The beamline Dewar accommodates three compact sample cassettes (holding up to 96 samples each). During the past 4 months the system on beamline 11?1 has been used to screen over 1000 crystals. The system has reduced both screening time and manpower. Integration of the hardware components is accomplished in the Distributed Control System architecture developed at SSRL (McPhillips et al. J. Synchrotron Rad. (2002) 9 401406). A crystal?screening interface has been implemented in Blu?Ice. Sample details can be uploaded from an Excel spreadsheet. The JCSG generates these spreadsheets automatically from their tracking database using standard database tools (http://www.jcsg.org). New diffraction image analysis tools are being employed to aid in extracting results. Automation also permits tele?presence. For example samples have been changed during the night without leaving home and scientists have screened crystals 1600 miles from the beamline. The system developed on beamline 11?1 has been replicated onto 1?5 9?1 9?2 and 11?3 and is used by both general users and the JCSG.

Mitchell D. Miller; Linda S. Brinen; Aina Cohen; Ashley M. Deacon; Paul Ellis; Scott E. McPhillips; Timothy M. McPhillips; R. Paul Phizackerley; S. Michael Soltis; Henry van den Bedem; Gnter Wolf; Qingping Xu; Zepu Zhang

2004-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "integrated high throughput" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


141

High-throughput film-densitometry: An efficient approach to generate large data sets  

SciTech Connect

A film-handling machine (robot) has been built which can, in conjunction with a commercially available film densitometer, exchange and digitize over 300 electron micrographs per day. Implementation of robotic film handling effectively eliminates the delay and tedium associated with digitizing images when data are initially recorded on photographic film. The modulation transfer function (MTF) of the commercially available densitometer is significantly worse than that of a high-end, scientific microdensitometer. Nevertheless, its signal-to-noise ratio (S/N) is quite excellent, allowing substantial restoration of the output to ''near-to-perfect'' performance. Due to the large area of the standard electron microscope film that can be digitized by the commercial densitometer (up to 10,000 x 13,680 pixels with an appropriately coded holder), automated film digitization offers a fast and inexpensive alternative to high-end CCD cameras as a means of acquiring large amounts of image data in electron microscopy.

Typke, Dieter; Nordmeyer, Robert A.; Jones, Arthur; Lee, Juyoung; Avila-Sakar, Agustin; Downing, Kenneth H.; Glaeser, Robert M.

2004-07-14T23:59:59.000Z

142

Integrated microfluidic device for single-cell high throughput screening in dynamic gene expression analysis  

E-Print Network (OSTI)

programs (e.g. AutoCAD, Autodesk Inc. or Adobe Illustrator,such as AutoCAD 2005 (Autodesk Inc. ), and printed at 20,000Adobe) and AutoCAD (Autodesk Inc. ), printed on transparent

Hui, Lawrence Kwan Yeung

2008-01-01T23:59:59.000Z

143

Integrated microfluidic device for single-cell high throughput screening in dynamic gene expression analysis  

E-Print Network (OSTI)

P.J. , & Lee, L.P. , Microfluidics-based systems biology.T.M. & Quake, S.R. , Microfluidics: Fluid physics at theand applications of microfluidics in biology. Annu Rev

Hui, Lawrence Kwan Yeung

2008-01-01T23:59:59.000Z

144

Integrated microfluidic device for single-cell high throughput screening in dynamic gene expression analysis.  

E-Print Network (OSTI)

??Over the past decade, interest in microfluidics has surged as applications have trended towards novel biological assays. Specifically, the ability of microfluidics to parallelize cellular (more)

Hui, Lawrence Kwan Yeung

2008-01-01T23:59:59.000Z

145

A High-Throughput Study of PtNiZr Catalysts for Application in PEM Fuel Cells  

SciTech Connect

The effects of adding Zr to PtNi oxygen reduction reaction (ORR) electrocatalyst alloys were examined in a study aimed at probing the possibility of creating catalysts with enhanced resistance to corrosion in a PEM fuel cell environment. Samples consisting of pure Pt or PtNiZr alloys with a range of compositions (not exceeding 11 at.% Zr) were fabricated using co-sputter deposition. A high-throughput fabrication approach was used wherein 18 distinct thin film catalyst alloy samples with varying compositions were deposited onto a large-area substrate with individual Au current collector structures. A multi-channel pseudo-potentiostat allowed for the simultaneous quantitative study of catalytic activity for all 18 electrodes in a single test bath, a first for the study of ORR electrocatalysts. A properly stirred oxygenated 1 M H{sub 2}SO{sub 4} electrolyte solution was used to provide each electrode with a steady-state flow of reactants during electrochemical evaluation. The onset potentials, absolute current density values, and Tafel analysis data obtained using this technique were compared with literature reports. The analyses showed that most PtNiZr alloys tested offered improvements over pure Pt, however those surfaces with a high mole fraction (>4 at.%) of Zr exhibited reduced activity that was roughly inversely correlated to the amount of Zr present. Film composition, morphology, and crystallographic properties were examined using X-ray energy dispersive spectroscopy (XEDS), X-ray photoelectron spectroscopy (XPS), SEM, and synchrotron X-ray diffraction. These data were then correlated with electrochemical data to elucidate the relationships between composition, structure, and relative performance for this ternary system.

Whitacre, J.F.; Valdez, T.I.; Narayanan, S.R.

2009-05-26T23:59:59.000Z

146

AMD 601 High Integrity -Magnesium Automotive Components (HI-MAC...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

AMD 601 High Integrity -Magnesium Automotive Components (HI-MAC) AMD 601 High Integrity -Magnesium Automotive Components (HI-MAC) Presentation from the U.S. DOE Office of Vehicle...

147

NREL: Energy Systems Integration Facility - High-Performance...  

NLE Websites -- All DOE Office Websites (Extended Search)

High-Performance Computing and Analytics High-performance computing and analytic capabilities at the Energy Systems Integration Facility enable study and simulation of material...

148

High Efficiency Microturbine with Integral Heat Recovery - Presentatio...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

High Efficiency Microturbine with Integral Heat Recovery - Fact Sheet, 2014 2011 CHPIndustrial Distributed Energy R&D Portfolio Review - Summary Report AMO Peer Review,...

149

High Temperature Integrated Thermoelectric Ststem and Materials  

SciTech Connect

The final goal of this project is to produce, by the end of Phase II, an all ceramic high temperature thermoelectric module. Such a module design integrates oxide ceramic n-type, oxide ceramic p-type materials as thermoelectric legs and oxide ceramic conductive material as metalizing connection between n-type and p-type legs. The benefits of this all ceramic module are that it can function at higher temperatures (> 700 C), it is mechanically and functionally more reliable and it can be scaled up to production at lower cost. With this all ceramic module, millions of dollars in savings or in new opportunities recovering waste heat from high temperature processes could be made available. A very attractive application will be to convert exhaust heat from a vehicle to reusable electric energy by a thermoelectric generator (TEG). Phase I activities were focused on evaluating potential n-type and p-type oxide compositions as the thermoelectric legs. More than 40 oxide ceramic powder compositions were made and studied in the laboratory. The compositions were divided into 6 groups representing different material systems. Basic ceramic properties and thermoelectric properties of discs sintered from these powders were measured. Powders with different particles sizes were made to evaluate the effects of particle size reduction on thermoelectric properties. Several powders were submitted to a leading thermoelectric company for complete thermoelectric evaluation. Initial evaluation showed that when samples were sintered by conventional method, they had reasonable values of Seebeck coefficient but very low values of electrical conductivity. Therefore, their power factors (PF) and figure of merits (ZT) were too low to be useful for high temperature thermoelectric applications. An unconventional sintering method, Spark Plasma Sintering (SPS) was determined to produce better thermoelectric properties. Particle size reduction of powders also was found to have some positive benefits. Two composition systems, specifically 1.0 SrO - 0.8 x 1.03 TiO2 - 0.2 x 1.03 NbO2.5 and 0.97 TiO2 - 0.03 NbO2.5, have been identified as good base line compositions for n-type thermoelectric compositions in future module design. Tests of these materials at an outside company were promising using that company's processing and material expertise. There was no unique p-type thermoelectric compositions identified in phase I work other than several current cobaltite materials. Ca3Co4O9 will be the primary p-type material for the future module design until alternative materials are developed. BaTiO3 and rare earth titanate based dielectric compositions show both p-type and n-type behavior even though their electrical conductivities were very low. Further research and development of these materials for thermoelectric applications is planned in the future. A preliminary modeling and optimization of a thermoelectric generator (TEG) that uses the n-type 1.0 SrO - 1.03 x 0.8 TiO2 - 1.03 x 0.2 NbO2.5 was performed. Future work will combine development of ceramic powders and manufacturing expertise at TAM, development of SPS at TAM or a partner organization, and thermoelectric material/module testing, modeling, optimization, production at several partner organizations.

Mike S. H. Chu

2011-06-06T23:59:59.000Z

150

The MeDICi Integration Framework: A Platform for High Performance Data Streaming Applications  

SciTech Connect

Building high performance analytical applications for data streams generated from sensors is a challenging software engineering problem. Such applications typically comprise a complex pipeline of processing components that capture, transform and analyze the incoming data stream. In addition, applications must provide high throughput, be scalable, and easily modifiable so that new analytical components can be added with minimum effort. In this paper we describe the MeDICi Integration Framework (MIF), which is a middleware platform we have created to address these challenges. The MIF extends an open source messaging platform with a component-based API for integrating components into analytical pipelines. We describe the features and capabilities of the MIF, and show how it has been used to build a production analytical application for detecting cyber security attacks. The application was composed from multiple independently developed components using several different programming languages. The resulting application was able to process network sensor traffic in real time and provide insightful feedback to network analysts as soon as potential attacks were recognized.

Gorton, Ian; Wynne, Adam S.; Almquist, Justin P.; Chatterton, Jack

2008-02-22T23:59:59.000Z

151

High Speed Flywheels for Integrated Energy Storage and Attitude Control  

E-Print Network (OSTI)

High Speed Flywheels for Integrated Energy Storage and Attitude Control Christopher D. Hall. Decomposition of the space of internal torques separates the attitude control functionfrom the energy storage simultaneously performing energy storage and extraction operations. 1 Introduction The power engineering

Hall, Christopher D.

152

Structural Integrity Assessment of Very High Temperature Nuclear...  

NLE Websites -- All DOE Office Websites (Extended Search)

Structural Integrity Assessment of Very High Temperature Nuclear Reactor Core Components Oct 20 2014 09:00 AM - 10:00 AM Gyanendar Singh, The University of Minnesota, Minneapolis...

153

High-Level Liquid Waste Tank Integrity Workshop - 2008  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Liquid Waste Tank Integrity Liquid Waste Tank Integrity Workshop - 2008 Karthik Subramanian Bruce Wiersma November 2008 High Level Waste Corporate Board Meeting karthik.subramanian@srnl.doe.gov bruce.wiersma@srnl.doe.gov 2 Acknowledgements * Bruce Wiersma (SRNL) * Kayle Boomer (Hanford) * Michael T. Terry (Facilitator) * SRS - Liquid Waste Organization * Hanford Tank Farms * DOE-EM 3 Background * High level radioactive waste (HLW) tanks provide critical interim confinement for waste prior to processing and permanent disposal * Maintaining structural integrity (SI) of the tanks is a critical component of operations 4 Tank Integrity Workshop - 2008 * Discuss the HLW tank integrity technology needs based upon the evolving waste processing and tank closure requirements along with its continued storage mission

154

Development of economically viable, highly integrated, highly modular SEGIS architecture.  

SciTech Connect

Initiated in 2008, the SEGIS initiative is a partnership involving the U.S. DOE, Sandia National Laboratories, private sector companies, electric utilities, and universities. Projects supported under the initiative have focused on the complete-system development of solar technologies, with the dual goal of expanding renewable PV applications and addressing new challenges of connecting large-scale solar installations in higher penetrations to the electric grid. Petra Solar, Inc., a New Jersey-based company, received SEGIS funds to develop solutions to two of these key challenges: integrating increasing quantities of solar resources into the grid without compromising (and likely improving) power quality and reliability, and moving the design from a concept of intelligent system controls to successful commercialization. The resulting state-of-the art technology now includes a distributed photovoltaic (PV) architecture comprising AC modules that not only feed directly into the electrical grid at distribution levels but are equipped with new functions that improve voltage stability and thus enhance overall grid stability. This integrated PV system technology, known as SunWave, has applications for 'Power on a Pole,' and comes with a suite of technical capabilities, including advanced inverter and system controls, micro-inverters (capable of operating at both the 120V and 240V levels), communication system, network management system, and semiconductor integration. Collectively, these components are poised to reduce total system cost, increase the system's overall value and help mitigate the challenges of solar intermittency. Designed to be strategically located near point of load, the new SunWave technology is suitable for integration directly into the electrical grid but is also suitable for emerging microgrid applications. SunWave was showcased as part of a SEGIS Demonstration Conference at Pepco Holdings, Inc., on September 29, 2011, and is presently undergoing further field testing as a prelude to improved and expanded commercialization.

Enslin, Johan (Petra Solar, Inc., South Plainfield, NJ); Hamaoui, Ronald (Petra Solar, Inc., South Plainfield, NJ); Gonzalez, Sigifredo; Haddad, Ghaith (Petra Solar, Inc., South Plainfield, NJ); Rustom, Khalid (Petra Solar, Inc., South Plainfield, NJ); Stuby, Rick (Petra Solar, Inc., South Plainfield, NJ); Kuran, Mohammad (Petra Solar, Inc., South Plainfield, NJ); Mark, Evlyn (Petra Solar, Inc., South Plainfield, NJ); Amarin, Ruba (Petra Solar, Inc., South Plainfield, NJ); Alatrash, Hussam (Petra Solar, Inc., South Plainfield, NJ); Bower, Ward Isaac; Kuszmaul, Scott S.; Sena-Henderson, Lisa; David, Carolyn; Akhil, Abbas Ali

2012-03-01T23:59:59.000Z

155

A six-axis robotic sample changer for high-throughput neutron powder diffraction and texture measurements  

Science Journals Connector (OSTI)

A new six-axis robotic sample changer for neutron powder diffraction experiments, including texture measurements, has enabled a novel set of experiments to be performed at the High-Pressure Preferred Orientation diffractometer at the Lujan Neutron Scattering Center.

Losko, A.S.

2014-11-18T23:59:59.000Z

156

High-Throughput Screen Identifies Novel Inhibitors of Cancer Biomarker ?-Methylacyl Coenzyme A Racemase (AMACR/P504S)  

Science Journals Connector (OSTI)

...opposite stereoisomer after diastereomeric separation using either gas chromatography (GC) or high-performance liquid chromatography...Biochim Biophys Acta 1997;1347:62-8. 26. Carnell AJ , Hale I, Denis S, Wanders RJ, Isaacs WB, Wilson BA, et alDesign...

Brice A.P. Wilson; Haofan Wang; Benjamin A. Nacev; Ronnie C. Mease; Jun O. Liu; Martin G. Pomper; and William B. Isaacs

2011-05-01T23:59:59.000Z

157

Simulation and Modeling Techniques for Signal Integrity and Electromagnetic Interference on High Frequency Electronic Systems.  

E-Print Network (OSTI)

Simulation and Modeling Techniques for Signal Integrity and Electromagnetic Interference on High and Modeling Techniques for Signal Integrity and Electromagnetic Interference on High Frequency Electronic Integrity and Electromagnetic Interference on High Frequency Electronic Systems. by Luca Daniel Doctor

Daniel, Luca

158

Development of high through-put Sr isotope analysis for monitoring reservoir integrity for CO{sub 2} storage.  

SciTech Connect

Recent innovations in multi-collector ICP-mass spectrometry (MC-ICP-MS) have allowed for rapid and precise measurements of isotope ratios in geological samples. Naturally occurring Sr isotopes has the potential for use in Monitoring, Verification, and Accounting (MVA) associated with geologic CO2 storage. Sr isotopes can be useful for: Sensitive tracking of brine migration; Determining seal rock leakage; Studying fluid/rock reactions. We have optimized separation chemistry procedures that will allow operators to prepare samples for Sr isotope analysis off site using rapid, low cost methods.

Wall, Andy; Jain, Jinesh; Stewart, Brian; Capo, Rosemary; Hakala, Alexandra J.; Hammack, Richard; Guthrie, George

2012-01-01T23:59:59.000Z

159

High Density Polymer-Based Integrated Electgrode Array  

DOE Patents (OSTI)

A high density polymer-based integrated electrode apparatus that comprises a central electrode body and a multiplicity of arms extending from the electrode body. The central electrode body and the multiplicity of arms are comprised of a silicone material with metal features in said silicone material that comprise electronic circuits.

Maghribi, Mariam N. (Livermore, CA); Krulevitch, Peter A. (Pleasanton, CA); Davidson, James Courtney (Livermore, CA); Hamilton, Julie K. (Tracy, CA)

2006-04-25T23:59:59.000Z

160

High-Q integrated on-chip microring resonator.  

SciTech Connect

We report a fully integrated high-Q factor micro-ring resonator using silicon nitride/dioxide on a silicon wafer. The micro-ring resonator is critically coupled to a low loss straight waveguide. An intrinsic quality factor of 2.4 x 10{sup 5} has been measured.

Sullivan, Charles Thomas; Vawter, Gregory Allen; Esherick, Peter; Guo, Junpeng; Shaw, Michael J.; Hadley, G. Ronald

2005-03-01T23:59:59.000Z

Note: This page contains sample records for the topic "integrated high throughput" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


161

High-performance spider webs: integrating biomechanics, ecology and behaviour  

Science Journals Connector (OSTI)

...articles 1004 25 High-performance spider webs: integrating biomechanics, ecology and...materials in both strength and toughness. Orb-web spider dragline silk is the focus of intense...silks is often removed from the context of web ecology and spider foraging behaviour...

2011-01-01T23:59:59.000Z

162

High-Throughput Plasmonic Nanolithography  

E-Print Network (OSTI)

Some of the materials allow reversible phase change and areto change the phase for a semispherical material volume withto change the phase for a semispherical material volume of

Pan, Liang

2010-01-01T23:59:59.000Z

163

High throughput reproducible cantilever functionalization  

DOE Patents (OSTI)

A method for functionalizing cantilevers is provided that includes providing a holder having a plurality of channels each having a width for accepting a cantilever probe and a plurality of probes. A plurality of cantilever probes are fastened to the plurality of channels of the holder by the spring clips. The wells of a well plate are filled with a functionalization solution, wherein adjacent wells in the well plate are separated by a dimension that is substantially equal to a dimension separating adjacent channels of the plurality of channels. Each cantilever probe that is fastened within the plurality of channels of the holder is applied to the functionalization solution that is contained in the wells of the well plate.

Evans, Barbara R; Lee, Ida

2014-01-21T23:59:59.000Z

164

High-Throughput Plasmonic Nanolithography  

E-Print Network (OSTI)

by a thin layer of Perfluoropolyether (PFPE) as a lubricant2-nm thick lubricant Perfluoropolyether (PFPE) was also dip-

Pan, Liang

2010-01-01T23:59:59.000Z

165

High-Throughput Plasmonic Nanolithography  

E-Print Network (OSTI)

gap between the flying PL arrays and disk surface. (a) (b) (gap between the flying PL arrays and disk surface. As shown3 N 4 overcoats. Both disks and flying heads were examined

Pan, Liang

2010-01-01T23:59:59.000Z

166

High-throughput Process Development  

E-Print Network (OSTI)

.2 Screening experiments in PreDictor plates vs small-scale columns....................................5 1 Chromatography Principles and Methods 18-1022-29 Antibody Purification Handbook 18-1037-46 Ion Exchange Protein Purification Handbook Principles and Methods 18-1142-75 Protein Purification Handbook 18

Lebendiker, Mario

167

Technical Report: Scalable Parallel Algorithms for High Dimensional Numerical Integration  

SciTech Connect

We implemented a scalable parallel quasi-Monte Carlo numerical high-dimensional integration for tera-scale data points. The implemented algorithm uses the Sobol s quasi-sequences to generate random samples. Sobol s sequence was used to avoid clustering effects in the generated random samples and to produce low-discrepancy random samples which cover the entire integration domain. The performance of the algorithm was tested. Obtained results prove the scalability and accuracy of the implemented algorithms. The implemented algorithm could be used in different applications where a huge data volume is generated and numerical integration is required. We suggest using the hyprid MPI and OpenMP programming model to improve the performance of the algorithms. If the mixed model is used, attention should be paid to the scalability and accuracy.

Masalma, Yahya [Universidad del Turabo; Jiao, Yu [ORNL

2010-10-01T23:59:59.000Z

168

2011 DoD High Performance Computing Modernization Program Users Group Conference A Web-based High-Throughput Tool for Next-Generation Sequence Annotation  

E-Print Network (OSTI)

320 2011 DoD High Performance Computing Modernization Program Users Group Conference A Web deployed on the Mana Linux cluster at the Maui High Performance Computing Center. The two components

169

EVSE Features Low and High Current Settings Integrated Flashlight  

NLE Websites -- All DOE Office Websites (Extended Search)

Low and High Current Settings Integrated Flashlight Low and High Current Settings Integrated Flashlight Auto-restart EVSE Specifications Grid connection Plug and cord NEMA 5-15 Connector type J1772 Test lab certifications ETL Listed Approximate size (H x W x D inches) 16 x 9 x 4 Charge level AC Level 1 Input voltage 120 VAC Maximum input current 12 Amp Circuit breaker rating 20 Amp Test Conditions 1 Test date 9/4/2012 Nominal supply voltage (Vrms) 117.05 Supply frequency (Hz) 59.99 Initial ambient temperature (°F) 58 Test Vehicle 1,3 Make and model 2012 Chevrolet Volt Battery type Li-ion Steady state charge power (AC kW) 1.36 Maximum charge power (AC kW) 1.45 EVSE Test Results 1,2,4 EVSE consumption prior to charge (AC W) 3.6

170

Achieving High Reliability Operations Through Multi-Program Integration  

SciTech Connect

Over the last 20 years the Idaho National Laboratory (INL) has adopted a number of operations and safety-related programs which has each periodically taken its turn in the limelight. As new programs have come along there has been natural competition for resources, focus and commitment. In the last few years, the INL has made real progress in integrating all these programs and are starting to realize important synergies. Contributing to this integration are both collaborative individuals and an emerging shared vision and goal of the INL fully maturing in its high reliability operations. This goal is so powerful because the concept of high reliability operations (and the resulting organizations) is a masterful amalgam and orchestrator of the best of all the participating programs (i.e. conduct of operations, behavior based safety, human performance, voluntary protection, quality assurance, and integrated safety management). This paper is a brief recounting of the lessons learned, thus far, at the INL in bringing previously competing programs into harmony under the goal (umbrella) of seeking to perform regularly as a high reliability organization. In addition to a brief diagram-illustrated historical review, the authors will share the INLs primary successes (things already effectively stopped or started) and the gaps yet to be bridged.

Holly M. Ashley; Ronald K. Farris; Robert E. Richards

2009-04-01T23:59:59.000Z

171

Integrative seismic safety evaluation of a high concrete arch dam  

Science Journals Connector (OSTI)

Abstract An integrative seismic safety evaluation of an arch dam should include all sources of nonlinearities, dynamic interactions between different components and the external loads. The present paper investigates the calibration procedure and nonlinear seismic response of an existing high arch dam. The first part explains the conducted analyses for the static and thermal calibrations of the dam based on site measurements. The second part investigates the nonlinear seismic analysis of the calibrated model considering the effect of joints, cracking of mass concrete, reservoirdamrock interaction, hydrodynamic pressure inside the opened joints and the geometric nonlinearity. Penetration of the water inside the opened joints accelerates the damage process. The integrative seismic assessment of a case study shows that the dam will fail under the maximum credible earthquake scenario. The dam is judged to be severely damaged with extensive cracking and the joints undergo opening/sliding. A systematic procedure is proposed for seismic and post-seismic safety of dams.

M.A. Hariri-Ardebili; M.R. Kianoush

2014-01-01T23:59:59.000Z

172

Design, Implementation and Performance of Exponential Integrators for High Performance Computing Applications  

E-Print Network (OSTI)

interest in high performance computing would help popularizeIntegrators for High Performance Computing Applications Aapplied mathematics, high performance computing and computer

Loffeld, John

2013-01-01T23:59:59.000Z

173

A new integrated pixel detector for high energy physics  

SciTech Connect

In this paper, the authors have fabricated integrated pixel devices which have the high-resistivity, signal-charge collecting volume and the readout circuitry in a single piece of silicon. The integration of both detecting elements and circuitry is carried out by building the circuitry on top of the detecting elements maximizing spatial resolution. Loss of signal charge into the circuitry where it would be lost for readout is avoided. Both circuitry and detecting elements are fully functional. Tests with infrared illumination and gamma irradiation have been carried out on wafer before dicing and packaging. Here the authors present noise measurements illustrating the excellent signal to single-channel noise performance of this device of about 150 to 1 for a minimum ionizing particle, which is an order of magnitude better than silicon strip detectors currently used. The authors also made a setup for packaged devices, and gamma irradiation measurement results obtained with this setup illustrate the high signal to noise performance and good uniformity in sensitivity over the different pixels.

Snoeys, W.; Plummer, J. (Stanford Univ., CA (United States). Center for Integrated Systems); Parker, S.; Kenney, C. (Hawaii Univ., Honolulu, HI (United States))

1992-10-01T23:59:59.000Z

174

Development of FRET-based Technologies for Dynamic and Quantitative Measurement of Protein-protein Interactions and High-throughput Screening of Small Chemical Inhibitors of the SUMO Pathway  

E-Print Network (OSTI)

throughput platform to screen small chemical compounds thatscreening platforms to look for small chemical inhibitorsplatform provides a new strategy to identify small chemical

Song, Yang

2011-01-01T23:59:59.000Z

175

Development of High-Capacity Cathode Materials with Integrated...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

safety Integrated structure: creation of spinel components in the layered- layered nano-composite structure to improve rate performance * Demonstration of improved...

176

Integrating Structure Control over Multiple Length Scales in Porous High  

E-Print Network (OSTI)

temperature catalytic applications for their high surface area and low flow resistance in combination with thermal and chemical stability. We have developed a bottom-up approach to functional, porous, high results in three-dimensionally interconnected, high-temperature ceramic materials functionalized with well

Gruner, Sol M.

177

Abstract 3173: High-throughput, systematic analysis of paired-end next-generation sequencing data to characterize the gene fusion landscape in cancer.  

Science Journals Connector (OSTI)

...TopHat) for further method development. An analysis pipeline was developed and executed in parallel on a high-performance computing cluster. Filtering and annotation was conducted on the aggregated data as a post-processing step, to enable...

Seth E. Sadis; Nickolay A. Khazanov; Armand R. Bankhead; Dinesh Cyanam; Paul D. Williams; Sean F. Eddy; Peter J. Wyngaard; Daniel R. Rhodes

2013-08-14T23:59:59.000Z

178

Data Integration for the Generation of High Resolution Reservoir Models  

SciTech Connect

The goal of this three-year project was to develop a theoretical basis and practical technology for the integration of geologic, production and time-lapse seismic data in a way that makes best use of the information for reservoir description and reservoir performance predictions. The methodology and practical tools for data integration that were developed in this research project have been incorporated into computational algorithms that are feasible for large scale reservoir simulation models. As the integration of production and seismic data require calibrating geological/geostatistical models to these data sets, the main computational tool is an automatic history matching algorithm. The following specific goals were accomplished during this research. (1) We developed algorithms for calibrating the location of the boundaries of geologic facies and the distribution of rock properties so that production and time-lapse seismic data are honored. (2) We developed and implemented specific procedures for conditioning reservoir models to time-lapse seismic data. (3) We developed and implemented algorithms for the characterization of measurement errors which are needed to determine the relative weights of data when conditioning reservoir models to production and time-lapse seismic data by automatic history matching. (4) We developed and implemented algorithms for the adjustment of relative permeability curves during the history matching process. (5) We developed algorithms for production optimization which accounts for geological uncertainty within the context of closed-loop reservoir management. (6) To ensure the research results will lead to practical public tools for independent oil companies, as part of the project we built a graphical user interface for the reservoir simulator and history matching software using Visual Basic.

Albert Reynolds; Dean Oliver; Gaoming Li; Yong Zhao; Chaohui Che; Kai Zhang; Yannong Dong; Chinedu Abgalaka; Mei Han

2009-01-07T23:59:59.000Z

179

INTEGRATION OF HIGH TEMPERATURE GAS REACTORS WITH IN SITU OIL SHALE RETORTING  

SciTech Connect

This paper evaluates the integration of a high-temperature gas-cooled reactor (HTGR) to an in situ oil shale retort operation producing 7950 m3/D (50,000 bbl/day). The large amount of heat required to pyrolyze the oil shale and produce oil would typically be provided by combustion of fossil fuels, but can also be delivered by an HTGR. Two cases were considered: a base case which includes no nuclear integration, and an HTGR-integrated case.

Eric P. Robertson; Michael G. McKellar; Lee O. Nelson

2011-05-01T23:59:59.000Z

180

Catalyst Structure-Performance Relationship Identified by High...  

NLE Websites -- All DOE Office Websites (Extended Search)

Identified by High-Throughput Operando Method: New Insight for Silica-Supported Catalyst Structure-Performance Relationship Identified by High-Throughput Operando Method: New...

Note: This page contains sample records for the topic "integrated high throughput" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


181

Evaluation of a Solid-Phase Extraction Method for Benzoylecgonine Urine Analysis in a High-Throughput Forensic Urine Drug-Testing Laboratory  

Science Journals Connector (OSTI)

......high-volume production facility reducing overall cost of analysis by...minimizing waste production while meeting...Forensic Medicine Gas Chromatography-Mass...minimizing waste production while meeting...street at lower cost and higher purity...confirmation by gas chromatog- raphy-mass......

Peter R. Stout; Jay M. Gehlhausen; Carl K. Horn; Kevin L. Klette

2002-10-01T23:59:59.000Z

182

Development of a membrane impregnated with a poly(dimethylsiloxane)/poly(ethylene glycol) copolymer for a high-throughput screening of the permeability of drugs, cosmetics, and other chemicals across the human skin  

Science Journals Connector (OSTI)

Abstract We aimed to develop a high-throughput screening (HTS) system for preliminary predictions of human skin permeability by using an artificial membrane that can mimic the permeation behaviour of lipophilic and hydrophilic compounds across the human skin. In this study, we synthesized a copolymer containing poly(dimethylsiloxane) (PDMS) and poly(ethylene glycol) (PEG) 6000 and impregnated it onto a supportive membrane filter to prepare a PDMS/PEG 6000 copolymer-impregnated membrane. In addition, we synthesized another polymer without PEG units and used it to prepare an impregnated membrane for determining the role of PEG 6000 units in the PDMS/PEG 6000 copolymer-impregnated membrane. The permeation characteristics of the impregnated membranes were evaluated on the basis of the permeability coefficients of 12 model compounds with different lipophilicities, by using a 2-chamber diffusion cell, and these permeability coefficients were compared with those across the human skin. We obtained a good correlation between the permeability coefficients across the PDMS/PEG 6000 copolymer-impregnated membrane and human skin. Further, we evaluated the permeation characteristics of a 96-well plate model of the PDMS/PEG 6000 copolymer by using 6 model compounds. We obtained an ideal correlation between the permeability coefficients across the PDMS/PEG 6000 copolymer using a 96-well plate and those across the human skin. Thus, the PDMS/PEG 6000 copolymer would be a good candidate for preliminary evaluation of the permeability of lipophilic and hydrophilic compounds across the human skin.

Ryotaro Miki; Yasuna Ichitsuka; Takumi Yamada; Soichiro Kimura; Yuya Egawa; Toshinobu Seki; Kazuhiko Juni; Hideo Ueda; Yasunori Morimoto

2015-01-01T23:59:59.000Z

183

Integration of High-Temperature Gas-Cooled Reactors into Industrial Process Applications  

SciTech Connect

This report is a summary of analyses performed by the NGNP project to determine whether it is technically and economically feasible to integrate high temperature gas cooled reactor (HTGR) technology into industrial processes. To avoid an overly optimistic environmental and economic baseline for comparing nuclear integrated and conventional processes, a conservative approach was used for the assumptions and calculations.

Lee Nelson

2011-09-01T23:59:59.000Z

184

Integrated Concentration in Science, 2012 High Fructose Corn Syrup a mini iCons case study  

E-Print Network (OSTI)

Integrated Concentration in Science, 2012 High Fructose Corn Syrup� a mini iCons case study knowledge affect you? What iCons learning goals did you meet with this case study, and how? How could you

Auerbach, Scott M.

185

Current mode integrators and their applications in low-voltage high frequency CMOS signal processing  

E-Print Network (OSTI)

Low voltage CMOS fully differential integrators for high frequency continuous-time filters using current-mode techniques are presented.. Current mode techniques are employed to avoid the use of the floating differential pair, in order to achieve...

Smith, Sterling Lane

2012-06-07T23:59:59.000Z

186

High Efficiency Microturbine with Integral Heat Recovery- Presentation by Capstone Turbine Corporation, June 2011  

Energy.gov (U.S. Department of Energy (DOE))

Presentation on High Efficiency Microturbine with Integral Heat Recovery, given by John Nourse of Capstone Turbine Corporation, at the U.S. DOE Industrial Distributed Energy Portfolio Review Meeting in Washington, D.C. on June 1-2, 2011.

187

High resolution reanalysis of wind speeds over the British Isles for wind energy integration  

E-Print Network (OSTI)

The UK has highly ambitious targets for wind development, particularly offshore, where over 30GW of capacity is proposed for development. Integrating such a large amount of variable generation presents enormous challenges. ...

Hawkins, Samuel Lennon

2012-11-29T23:59:59.000Z

188

Correlated tuning of high-frequency integrated continuous-time filters  

E-Print Network (OSTI)

CORRELATED TUNING OF HIGH ? FREQUENCY INTEGRATED CONTINUOUS ? TIME FILTERS A Thesis TODD LEE BROOKS Submitted to the Once of Graduate Studies of Texas A&M University in partial fulfillment of the requirements for the degree of MASTER... OF SCIENCE May 1992 Major Subject: Electrical Engineering CORRELATED TUNING OF HIGH ? FREQUENCY INTEGRATED CONTINUOUS ? TIME FILTERS A Thesis by TODD LEE BROOKS Approved as to style and content by: Ran 11 L. Geiger (Co-Chair of Committee) William G...

Brooks, Todd Lee

2012-06-07T23:59:59.000Z

189

High performance CMOS integrated circuits for optical receivers  

E-Print Network (OSTI)

.7GHz for a 0.6pF photodiode capacitance. The power dissipations for the highest and the lowest gains are 8.2mW and 24.9mW respectively. A new technique for designing uniform multistage amplifiers (MA) for high frequency applications is introduced...

SamadiBoroujeni, MohammadReza

2009-05-15T23:59:59.000Z

190

Princeton Power Systems (TRL 5 6 Component)- Marine High-Voltage Power Conditioning and Transmission System with Integrated Energy Storage  

Energy.gov (U.S. Department of Energy (DOE))

Princeton Power Systems (TRL 5 6 Component) - Marine High-Voltage Power Conditioning and Transmission System with Integrated Energy Storage

191

Meandered-line antenna with integrated high-impedance surface.  

SciTech Connect

A reduced-volume antenna composed of a meandered-line dipole antenna over a finite-width, high-impedance surface is presented. The structure is novel in that the high-impedance surface is implemented with four Sievenpiper via-mushroom unit cells, whose area is optimized to match the meandered-line dipole antenna. The result is an antenna similar in performance to patch antenna but one fourth the area that can be deployed directly on the surface of a conductor. Simulations demonstrate a 3.5 cm ({lambda}/4) square antenna with a bandwidth of 4% and a gain of 4.8 dBi at 2.5 GHz.

Forman, Michael A.

2010-09-01T23:59:59.000Z

192

A fully integrated high-Q Whispering-Gallery Wedge Resonator  

E-Print Network (OSTI)

Microresonator devices which posses ultra-high quality factors are essential for fundamental investigations and applications. Microsphere and microtoroid resonators support remarkably high Q's at optical frequencies, while planarity constrains preclude their integration into functional lightwave circuits. Conventional semiconductor processing can also be used to realize ultra-high-Q's with planar wedge-resonators. Still, their full integration with side-coupled dielectric waveguides remains an issue. Here we show the full monolithic integration of a wedge-resonator/waveguide vertically-coupled system on a silicon chip. In this approach the cavity and the waveguide lay in different planes. This permits to realize the shallow-angle wedge while the waveguide remains intact, allowing therefore to engineer a coupling of arbitrary strength between these two. The precise size-control and the robustness against post-processing operation due to its monolithic integration makes this system a prominent platform for indu...

Ramiro-Manzano, F; Pavesi, L; Pucker, G; Ghulinyan, M

2012-01-01T23:59:59.000Z

193

Technology support for high-throughput processing of thin-film CdTe PV modules: Annual technical report, Phase 1, 1 April 1998--31 March 1999  

SciTech Connect

This report describes work performed by First Solar, L.L.C., during Phase 1 of this 3-year subcontract. The research effort of this subcontract is divided into four areas: (1) process and equipment development, (2) efficiency improvement, (3) characterization and analysis, and (4) environmental, health, and safety. As part of the process development effort, the output of the pilot-production facility was increased. More than 6,200 8-ft{sup 2} CdS/CdTe plates were produced during Phase 1--more than double the total number produced prior to Phase 1. This increase in pilot-production rate was accomplished without a loss in the PV conversion efficiency: the average total-area AM1.5 efficiency of sub-modules produced during the reporting period was 6.4%. Several measurement techniques, such as large-area measurement of CdS thickness, were developed to aid process improvement, and the vapor-transport deposition method was refined. CdTe thickness uniformity and reproducibility were improved. From a population of more than 1,100 plates, the mean standard deviation within a plate was 7.3% and the standard deviation of individual-plate averages was 6.8%. As part of the efficiency-improvement task, research was done on devices with thin-CdS and buffer layers. A cell with 13.9% efficiency was produced on a high-quality substrate, and higher than 12% efficiency was achieved with a cell with no CdS layer. A number of experiments were performed as part of the characterization and analysis task. The temperature dependence of CdTe modules was investigated; the power output was found to be relatively insensitive (<5%) to temperature in the 25 to 50 C range. As part of the characterization and analysis task, considerable effort was also given to reliability verification and improvement. The most carefully monitored array, located at the NREL, was found to have unchanged power output within the margin of error of measurement (5%) after 5 years in the field. The first round of National CdTe Team stability tests were concluded. One back-contact formulation resulted in cells that increased in efficiency as a result of 9,700 hours of light soaking. As part of the environmental, health, and safety task, an emissions survey was performed for the pilot-production facility. For production of 360 modules/day, it was predicted that the cadmium emissions would be only 0.015% of the level that would require any permitting; however, methanol emissions may require permitting if anticipated process changes are not implemented. Process improvements in edge delete, CdS material preparation, waste compaction, CdCl{sub 2}-vapor collection, and wastewater treatment were made, resulting in reduced costs, reduced emissions, and improved operator safety.

Rose, D.H.; Powell, R.C.; Grecu, D.; Jayamaha, U.; Hanak, J.J.; Bohland, J.; Smigielski, K.; Dorer, G.L.

1999-10-25T23:59:59.000Z

194

MATERIALS INTEGRATION FOR HIGH- PERFORMANCE PHOTOVOLTAICS BY WAFER BONDING  

E-Print Network (OSTI)

No thesis is an individual endeavor, and this thesis would not have been possible without the assistance of my collaborators and advisor and would have been unendurable without the support of my coworkers, friends, and family. I apologize in advance to anyone whom I might omit in this brief acknowledgement, but it is late and I am running out of time! In the summer of 2000, Harry Atwater agreed to allow me to transfer to his group from the chemical engineering department. I was discouraged and doubtful about my future at Caltech and in graduate school in general. Since giving me that chance he has been a great advisor with no shortage of encouragement or ideas. I am never sure if this is by design, but Harry has managed to inspire me to work hard and has given me countless ideas to pursue while always allowing me to feel that I have nearly complete freedom to pursue experiments that are interesting to me. While in Harrys group I had the good fortune to work closely with two post-doctoral scholars, Chang-Geun Ahn and Anna Fontcuberta i Morral. Chang-Geun was extremely helpful in getting the Ge/Si bonding project going and in optical and electrical characterization experiments. Anna was tough to work with because her energy level is so darned high, but she has also been very supportive and her high energy approach to research has pushed me to work

James Michael Zahler; James Michael Zahler

2005-01-01T23:59:59.000Z

195

On efficiency of integrative strategies among companies in US high-tech industry  

Science Journals Connector (OSTI)

Integration strategies are very important to the existence of businesses in globalised market. Most of the prior integration studies only considered the change of its own production efficiency without considering the change of the overall post-integration industry production efficiency. This study proposed the optimum efficiency model using data envelopment analysis (DEA) as the methodology. To do this, we took the analysis of US 20 high-tech industry as a practical application. We selected the capital expenditure, the sum of employees and R&D expense as input variables, and the net income and the technology strength of patent as output variables in 2007. This model can help firms in simulating the integrating results to predict the success of future integration.

Les Tien-Shang Lee

2010-01-01T23:59:59.000Z

196

High-Power InP-based Waveguide Photodiodes and Photodiode Arrays Heterogeneously Integrated on SOI  

E-Print Network (OSTI)

High-Power InP-based Waveguide Photodiodes and Photodiode Arrays Heterogeneously Integrated on SOI evanescently-coupled modified uni-traveling carrier photodiodes (MUTC PDs) on silicon-on-insulator (SOI on silicon is a promising approach to realize high-performance photodiodes on a silicon photonics platform

Bowers, John

197

High Throughput Materials Characterization John M. Gregoire  

NLE Websites -- All DOE Office Websites (Extended Search)

and groups where these activities take place are listed in the red boxes in the diagram above. A truly productive HiTp materials discovery pipeline, not unlike a structural...

198

A high-throughput distributed DNA  

E-Print Network (OSTI)

of royalty provided that (1) each reproduction is done without alteration and (2) the Journal reference, of this paper may be copied or distributed royalty free without further permission by computer-based and other

Weller, Jennifer Walsh

199

High-throughput hyperdimensional vertebrate phenotyping  

E-Print Network (OSTI)

Most gene mutations and biologically active molecules cause complex responses in animals that cannot be predicted by cell culture models. Yet animal studies remain too slow and their analyses are often limited to only a ...

Pardo-Martin, Carlos

200

High Throughput Single Molecule Investigation of Transcription  

E-Print Network (OSTI)

Dots. Nano Letters 9, 15981603. 4. Ebenstein, Y. , Gassman,Dots. Nano Letters 9, 1598-1603 (2009). Ebenstein, Y. ,

Kim, Soohong

2012-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "integrated high throughput" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


201

High Throughput Single Molecule Investigation of Transcription  

E-Print Network (OSTI)

Single Molecule Protein Folding in a Coaxial Mixer. Biophys.Kinetic Studies of Protein Folding. Anal. Chem. 76, 7169-Molecule Measurement of Protein Folding Kinetics . Science

Kim, Soohong

2012-01-01T23:59:59.000Z

202

Approaches to High Throughput Physical Organic Chemistry  

E-Print Network (OSTI)

compounds, using positive electrospray MS as the sole analytical tool. A version of the construct allowed HT reactivity profiling to be carried out on a range of ten carboxylic acids, ten aldehydes and ten isonitriles in the Ugi 4-component condensation...

Portal, Christophe

2008-01-01T23:59:59.000Z

203

Optimal Assembly for High Throughput Shotgun Sequencing  

E-Print Network (OSTI)

suf- ficient conditions for success in terms of repeat-between the sufficient condition guaranteeing the success ofby a read). Condition (a) K > ? interleaved for success of

Bresler, Guy; Bresler, Ma'ayan; Tse, David

2013-01-01T23:59:59.000Z

204

High throughput solar cell ablation system  

DOE Patents (OSTI)

A solar cell is formed using a solar cell ablation system. The ablation system includes a single laser source and several laser scanners. The laser scanners include a master laser scanner, with the rest of the laser scanners being slaved to the master laser scanner. A laser beam from the laser source is split into several laser beams, with the laser beams being scanned onto corresponding wafers using the laser scanners in accordance with one or more patterns. The laser beams may be scanned on the wafers using the same or different power levels of the laser source.

Harley, Gabriel; Pass, Thomas; Cousins, Peter John; Viatella, John

2012-09-11T23:59:59.000Z

205

High throughput solar cell ablation system  

DOE Patents (OSTI)

A solar cell is formed using a solar cell ablation system. The ablation system includes a single laser source and several laser scanners. The laser scanners include a master laser scanner, with the rest of the laser scanners being slaved to the master laser scanner. A laser beam from the laser source is split into several laser beams, with the laser beams being scanned onto corresponding wafers using the laser scanners in accordance with one or more patterns. The laser beams may be scanned on the wafers using the same or different power levels of the laser source.

Harley, Gabriel; Pass, Thomas; Cousins, Peter John; Viatella, John

2014-10-14T23:59:59.000Z

206

High throughput liquid absorption preconcentrator sampling instrument  

DOE Patents (OSTI)

A system for detecting trace concentrations of an analyte in air includes a preconcentrator for the analyte and an analyte detector. The preconcentrator includes an elongated tubular container comprising a wettable material. The wettable material is continuously wetted with an analyte-sorbing liquid which flows from one part of the container to a lower end. Sampled air flows through the container in contact with the wetted material with a swirling motion which results in efficient transfer of analyte vapors or aerosol particles to the sorbing liquid and preconcentration of traces of analyte in the liquid. The preconcentrated traces of analyte may be either detected within the container or removed therefrom for injection into a separate detection means or for subsequent analysis. 12 figs.

Zaromb, S.; Bozen, R.M.

1992-12-22T23:59:59.000Z

207

High Throughput Single Molecule Investigation of Transcription.  

E-Print Network (OSTI)

??RNA Polymerase (RNAP) is a crucial protein molecule that decodes the information stored in DNA as base pair sequences, through a process called transcription. The (more)

Kim, Soohong

2012-01-01T23:59:59.000Z

208

Initial Operation of the High Temperature Electrolysis Integrated Laboratory Scale Experiment at INL  

SciTech Connect

An integrated laboratory scale, 15 kW high-temperature electrolysis facility has been developed at the Idaho National Laboratory under the U.S. Department of Energy Nuclear Hydrogen Initiative. Initial operation of this facility resulted in over 400 hours of operation with an average hydrogen production rate of approximately 0.9 Nm3/hr. The integrated laboratory scale facility is designed to address larger-scale issues such as thermal management (feed-stock heating, high-temperature gas handling), multiple-stack hot-zone design, multiple-stack electrical configurations, and other integral issues. This paper documents the initial operation of the ILS, with experimental details about heat-up, initial stack performance, as well as long-term operation and stack degradation.

C. M. Stoots; J. E. O'Brien; K. G. Condie; J. S. Herring; J. J. Hartvigsen

2008-06-01T23:59:59.000Z

209

Recent advances in III-V on Si integration for high-efficiency,  

E-Print Network (OSTI)

. Iso-efficiency contour plots of ideal series-connected two-junction solar cell with an function of topRecent advances in III-V on Si integration for high-efficiency, low cost MJ cells Minjoo Larry Lee Department of Electrical Engineering Yale University Solar Workshop: Terawatt Challenge!!? UD Energy

Firestone, Jeremy

210

Integrated Process Configuration for High-Temperature Sulfur Mitigation during Biomass Conversion via Indirect Gasification  

Science Journals Connector (OSTI)

Integrated Process Configuration for High-Temperature Sulfur Mitigation during Biomass Conversion via Indirect Gasification ... National Bioenergy Center, National Renewable Energy Laboratory, 1617 Cole Blvd., Golden, Colorado 80401, United States ... Similar activation energies (9-10 kcal/mol) were measured for ZnO and Zn-Ti-O sulfidation. ...

Abhijit Dutta; Singfoong Cheah; Richard Bain; Calvin Feik; Kim Magrini-Bair; Steven Phillips

2012-05-23T23:59:59.000Z

211

Heat generation from electronics increases with the advent of high-density integrated circuit technology. To  

E-Print Network (OSTI)

1 Abstract Heat generation from electronics increases with the advent of high-density integrated circuit technology. To come up with the heat generation, microscale cooling has been thought as a promising technology. Prediction of heat transfer rate is crucial in design of microscale cooling device

Boyer, Edmond

212

Technical Report: Toward a Scalable Algorithm to Compute High-Dimensional Integrals of Arbitrary Functions  

SciTech Connect

Neutron experiments at the Spallation Neutron Source (SNS) at Oak Ridge National Laboratory (ORNL) frequently generate large amounts of data (on the order of 106-1012 data points). Hence, traditional data analysis tools run on a single CPU take too long to be practical and scientists are unable to efficiently analyze all data generated by experiments. Our goal is to develop a scalable algorithm to efficiently compute high-dimensional integrals of arbitrary functions. This algorithm can then be used to integrate the four-dimensional integrals that arise as part of modeling intensity from the experiments at the SNS. Here, three different one-dimensional numerical integration solvers from the GNU Scientific Library were modified and implemented to solve four-dimensional integrals. The results of these solvers on a final integrand provided by scientists at the SNS can be compared to the results of other methods, such as quasi-Monte Carlo methods, computing the same integral. A parallelized version of the most efficient method can allow scientists the opportunity to more effectively analyze all experimental data.

Snyder, Abigail C. [University of Pittsburgh; Jiao, Yu [ORNL

2010-10-01T23:59:59.000Z

213

Integrating High Penetrations of PV into Southern California: Year 2 Project Update; Preprint  

SciTech Connect

Southern California Edison (SCE) is well into a five-year project to install a total of 500 MW of distributed photovoltaic (PV) energy within its utility service territory. Typical installations to date are 1-3 MW peak rooftop PV systems that interconnect to medium-voltage urban distribution circuits or larger (5 MW peak) ground-mounted systems that connect to medium-voltage rural distribution circuits. Some of the PV system interconnections have resulted in distribution circuits that have a significant amount of PV generation compared to customer load, resulting in high-penetration PV integration scenarios. The National Renewable Energy Laboratory (NREL) and SCE have assembled a team of distribution modeling, resource assessment, and PV inverter technology experts in order to investigate a few of the high-penetration PV distribution circuits. Currently, the distribution circuits being studied include an urban circuit with a PV penetration of approximately 46% and a rural circuit with a PV penetration of approximately 60%. In both cases, power flow on the circuit reverses direction, compared to traditional circuit operation, during periods of high PV power production and low circuit loading. Research efforts during year two of the five-year project were focused on modeling the distribution system level impacts of high-penetration PV integrations, the development and installation of distribution circuit data acquisition equipment appropriate for quantifying the impacts of high-penetration PV integrations, and investigating high-penetration PV impact mitigation strategies. This paper outlines these research efforts and discusses the following activities in more detail: the development of a quasi-static time-series test feeder for evaluating high-penetration PV integration modeling tools; the advanced inverter functions being investigated for deployment in the project's field demonstration and a power hardware-in-loop test of a 500-kW PV inverter implementing a limited set of advanced inverter functions.

Mather, B.; Neal, R.

2012-08-01T23:59:59.000Z

214

Scientific Innovation Through Integration Capabilities Series  

NLE Websites -- All DOE Office Websites (Extended Search)

EMSL EMSL 's expansive mass spectrometry capability group enables high-throughput, high-resolution analysis of complex mixtures of many sample types. These world-class instruments and techniques are part of an unparalleled collection of capabilities designed for research that integrates experimental and computational tools. In particular, mass spectrometry at EMSL facilitates advanced global proteomics research, aerosol particle characterization, the study of ion-surface collisions, and materials characterization. These tools enable novel, fundamental research in EMSL's Science Themes of Biological Interactions and Dynamics, Geochemistry/ Biogeochemistry and Subsurface Science, and Science of Interfacial Phenomena. Specific research topics include:

215

Integration of Miniaturized Patch Antennas with High Dielectric-Constant Multilayer Packages and Soft-and-Hard Surfaces (SHS)  

E-Print Network (OSTI)

Integration of Miniaturized Patch Antennas with High Dielectric-Constant Multilayer Packages) is employed to suppress the surface wave generated by a patch antenna integrated with high dielectric capability of the SHS in surface-wave suppression. The first is a stacked patch antenna on a large

Tentzeris, Manos

216

Integrated high-resolution physical and comparative gene maps in horses  

E-Print Network (OSTI)

INTEGRATED HIGH-RESOLUTION PHYSICAL AND COMPARATIVE GENE MAPS IN HORSES A Dissertation by CANDICE LEA BRINKMEYER LANGFORD Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment... to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements for the degree of DOCTOR OF PHILOSOPHY Approved by: Chair of Committee, Bhanu P. Chowdhary Committee Members, James E. Womack Loren C...

Brinkmeyer Langford, Candice Lea

2007-04-25T23:59:59.000Z

217

Short note: A simplified technique for the efficient and highly accurate discretization of boundary integral equations in 2D on domains with corners  

Science Journals Connector (OSTI)

Keywords: Acoustic scattering, Boundary integral equation, Corner singularity, Direct solver, Grid refinement, High-order discretization, Nystrm discretization, Quadrature, Weakly singular integral equation

A. Gillman; S. Hao; P. G. Martinsson

2014-01-01T23:59:59.000Z

218

Implementations of the Integrated Linux, Windows and Macintosh Cluster for achieving the Personal High Performance Computing  

E-Print Network (OSTI)

SUMMARY The motivation and objective for this paper is to demonstrate (1) the integrated Linux (30 distributions, including Red Hat and SUSE), Windows (Cluster 2003 and Server 2003) and Macintosh (Tiger 10.4) cluster for running Web Services and jobs; and (2) the demonstration of the Personal High Performance Computing (PHPC), which only require a smaller number of computers, resources and space in the secure Gigabytes of 1,000 Mps and Wi-Fi/3G of 108 Mbps networking environments. This PHPC is based on a cluster of the 32-bit and 64-bit AMD and Intel dualcore machines, which can achieve the following: (a) jobs are shared amongst different platforms, which can run as a single job altogether or run different jobs concurrently; (b) running Java and.NET Web Services; (c) receiving up to a 60 % better performance referring to multi-tasking performance; (e) ensuring a secure networking environment, which includes VPN, in-build firewall and integrated wired and wireless networks; (f) storing a massive amount of data (12 TB, or 12,000 GB) for database and server applications; and (g) successfully integrating with other technologies such as the integrated Java and.NET Web Services,

Victor Chang

219

High Througput Combinatorial Techniques in Hydrogen Storage Materials R&D Workshop  

Energy.gov (U.S. Department of Energy (DOE))

Summary of the June 2007 high-throughput combinatorial techniques in hyrogen storage materials workshop

220

Savannah River Site (SRS) high level waste (HLW) structural integrity program  

SciTech Connect

The Savannah River Site has fifty-one underground tanks for radioactive waste storage and processing with doubly-contained piping systems for waste transfer. The SRS High Level Waste structural Integrity Program provides a process for evaluation and documenting material aging issues for structures, systems and components (SSC) in these facilities to maintain their confinement function. SRS has been monitoring waste, waste storage tanks, testing transfer lines and controlling waste chemistry for many years. A successful structural integrity (SI) program requires the following: detailed understanding of applicable degradation mechanisms; controlled chemistries and additions, as necessary; regular chemistry sampling and monitoring; structural capacity considerations; and a combination of on-line and periodic inspection and testing programs to provide early detection of generic degradation and verify effectiveness of the management of degradation under aging conditions identified by the SI Program. The application of these elements in the HLW SI Program achieves confinement in the facilities throughout desired service life.

Marra, J.E.; Abodishish, H.A.; Barnes, D.M.; Sindelar, R.L.; Flanders, H.E.; Houston, T.W.; Wiersma, B.J.; McNatt, F.G. Sr.; Cowfer, C.D. [Westinghouse Savannah River Co., Aiken, SC (United States)

1995-12-01T23:59:59.000Z

Note: This page contains sample records for the topic "integrated high throughput" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


221

Adaptation of Beef Cattle to Stressful Environments and Integrated Beef Systems for Production of Consistently Distinctive High-quality Beef  

E-Print Network (OSTI)

Adaptation of Beef Cattle to Stressful Environments and Integrated Beef Systems for Production. Integrated Beef Systems for the Production of Consistently Distinctive High-quality Beef Evaluation of system of system elements sensitive to product quality (e.g., genetics for adaptation, genetics characterizing

222

Integrating INIS into a high energy physics information environment thoughts from CERN  

E-Print Network (OSTI)

Information searchers from the high energy physics community expect an integrated information environment. The CERN Library offers its print and electronic collections through a combined Web interface and maintains the database by semi-automated processes to upload bibliographic and full-text records. Suggestions are offered by which INIS could develop its own Web interface and better match HEP users expectations. These include implementing full-text linking, increasing currency, expanding search and display functions and developing the richness of the data. Links with the National Nuclear Data Center and Crossref could also increase its visibility.

Yeomans, Joanne; Baudic, Romain; Picchioli, Ingrid; International Conference on Nuclear Knowledge Management : Strategies, Information Management and Human Resource Development. Special Session : The Role of INIS in Knowledge Preservation

2004-01-01T23:59:59.000Z

223

High-speed graphene interconnects monolithically integrated with CMOS ring oscillators operating at 1.3GHz  

E-Print Network (OSTI)

We have successfully experimentally integrated graphene interconnects with commercial 0.25 ¿m technology CMOS ring oscillator circuit using conventional fabrication techniques, and demonstrated high speed on-chip graphene ...

Chen, Xiangyu

224

Towards High-Fidelity Quantum Computation and Simulation on a Programmable Photonic Integrated Circuit  

E-Print Network (OSTI)

We propose and analyze the design of a programmable photonic integrated circuit for high-fidelity quantum computation and simulation. We demonstrate that the reconfigurability of our design allows us to overcome two major impediments to quantum optics on a chip: it removes the need for a full fabrication cycle for each experiment and allows for compensation of fabrication errors using numerical optimization techniques. Under a pessimistic fabrication model for the silicon-on-insulator process, we demonstrate a dramatic fidelity improvement for the linear optics CNOT and CPHASE gates and, showing the scalability of this approach, the iterative phase estimation algorithm built from individually optimized gates. We also propose and simulate a novel experiment that the programmability of our system would enable: a statistically robust study of the evolution of entangled photons in disordered quantum walks. Overall, our results suggest that existing fabrication processes are sufficient to build a quantum photonic processor capable of high fidelity operation.

Jacob Mower; Nicholas C. Harris; Gregory R. Steinbrecher; Yoav Lahini; Dirk Englund

2014-12-16T23:59:59.000Z

225

High-performance GaAs/AlGaAs optical phase modulators for microwave photonic integrated circuits  

SciTech Connect

A high-performance high-speed optical phase modulator for photonic integrated circuit (PIC) use is described. Integration of these optical phase modulators into a real system (compass) is also discussed. The optical phase modulators are based on depletion-edge translation and have experimentally provided optical phase shifts in excess of 60{degrees}/V{center_dot}mm with approximately 4 dB/cm loss while simultaneously demonstrating bandwidths in excess of 10 GHz.

Hietala, V.M.; Kravitz, S.H.; Armendariz, M.G.; Vawter, G.A.; Carson, R.F.

1994-03-01T23:59:59.000Z

226

Waveguide-integrated black phosphorus photodetector with high responsivity and low dark current  

E-Print Network (OSTI)

Layered two-dimensional materials have shown novel optoelectronic properties and are well suited to be integrated in planar photonic circuits. For example, graphene has been utilized as a wideband photodetector. However, because it lacks a band gap, graphene photodetectors suffer from extremely high dark current8. In contrast, few-layer black phosphorous, the latest addition to the family of 2D materials, is well-suited for photodetector applications due to its narrow but finite energy gap. Here, we demonstrate a gated multilayer black phosphorus photodetector integrated in a silicon photonic waveguide operating in the near-infrared telecom band. In a significant advantage over graphene devices, black phosphorus photodetectors can operate under a bias with very low dark current and attain intrinsic responsivity up to 125 mA/W and 657 mA/W in 11.5nm and 100 nm thick devices, respectively. The photocurrent is dominated by the photovoltaic effect with a high response bandwidth exceeding 3 GHz.

Youngblood, Nathan; Koester, Steven J; Li, Mo

2014-01-01T23:59:59.000Z

227

High temperature energy conversion for the Integrated Solar Upper Stage (ISUS)  

SciTech Connect

Preliminary studies were conducted to assess the benefits of the Integrated Solar Upper Stage (ISUS) concept and key components including high temperature thermionic converters, have been tested and evaluated. Advanced radiatively coupled heat pipe cooled thermionic converters with rhenium and tungsten emitters were characterized individually for integration in a modular power unit. The converter with the tungsten emitter was performance mapped in the temperature range of 1,750 K to 2,400 K in order to conform to the ISUS requirements. Higher off-design temperatures yielded power densities as high as 12 watts/sq. cm. in the cesium pressure range of 4 to 9 torr. The converter with the rhenium emitter was tested in the temperature range of 1,575 K to 1,950 K and produced 10.5 watts/sq. cm. at the highest temperature. Dynamic switching characteristics were also measured to evaluate the possibility of interfacing a pulse width modulated (PWM) power regulator directly to a thermionic source.

Ramalingam, M.L. [UES, Inc., Dayton, OH (United States); Lamp, T.R. [Wright Lab., Wright Patterson AFB, OH (United States); Jacox, M.; Kennedy, F. [Phillips Lab., Kirtland AFB, NM (United States)

1996-12-31T23:59:59.000Z

228

A pedagogical introduction to quantum integrability, with a view towards theoretical high-energy physics  

E-Print Network (OSTI)

These are lecture notes of an introduction to quantum integrability given at the Tenth Modave Summer School in Mathematical Physics, 2014, aimed at PhD candidates and junior researchers in theoretical physics. We introduce spin chains and discuss the coordinate Bethe Ansatz (CBA) for a representative example: the Heisenberg XXZ model. The focus lies on the structure of the CBA and on its main results, deferring a detailed treatment of the CBA for the general $M$-particle sector of the XXZ model to an appendix. Subsequently the transfer-matrix method is discussed for the six-vertex model, uncovering a relation between that model and the XXZ spin chain. Equipped with this background the quantum inverse-scattering method (QISM) and algebraic Bethe Ansatz (ABA) are treated. We emphasize the use of graphical notation for algebraic quantities as well as computations. Finally we turn to quantum integrability in the context of theoretical high-energy physics. We discuss factorized scattering in two-dimensional QFT, a...

Lamers, J

2015-01-01T23:59:59.000Z

229

High bandwidth Ge p-i-n photodetector integrated on Si  

SciTech Connect

The authors present a germanium on silicon p-i-n photodiode for vertical light incidence. For a Ge p-i-n photodetector with a radius of 5 {mu}m a 3 dB bandwidth of 25 GHz is measured at an incident wavelength of 1.55 {mu}m and zero external bias. For a modest reverse bias of 2 V, the 3 dB bandwidth increases to 39 GHz. The monolithically integrated devices are grown on Si with solid source molecular beam epitaxy. The complete detector structure consisting of a highly p-doped Ge buried layer, an intrinsic absorption region, and a highly n-doped top contact layer of Ge/Si is grown in one continuous epitaxial run. A low growth temperature sequence was needed to obtain abrupt doping transitions between the highly doped regions surrounding the intrinsic layer. A theoretical consideration of the 3 dB bandwidth of the Ge detector was used to optimize the layer structure. For a photodiode with 5 {mu}m mesa radius the maximum theoretical 3 dB frequency is 62 GHz with an intrinsic region thickness of 307 nm.

Oehme, M.; Werner, J.; Kasper, E.; Jutzi, M.; Berroth, M. [Institut fuer Halbleitertechnik, Universitaet Stuttgart, Pfaffenwaldring 47, 70569 Stuttgart (Germany); Institut fuer Elektrische und Optische Nachrichtentechnik, Universitaet Stuttgart, Pfaffenwaldring 47, 70569 Stuttgart (Germany)

2006-08-14T23:59:59.000Z

230

SCR-DPF Integrations for Diesel ExhaustPerformance and Perspectives for High SCR Loadings  

Energy.gov (U.S. Department of Energy (DOE))

Presents laboratory and engine bench test results from integrating the SCR catalyst into the diesel filter as one multifunctional unit.

231

Industrial Implementation of a Coordinator MPC for Maximizing Throughput at a  

E-Print Network (OSTI)

offshore fields. This set high demands, not only to the plant efficiency and its regularity, but alsoIndustrial Implementation of a Coordinator MPC for Maximizing Throughput at a Large-Scale Gas Plant°arstø gas plant is described. The "coordinator MPC" coordinates the flows through the network

Skogestad, Sigurd

232

Optimum Reactor Outlet Temperatures for High Temperature Gas-Cooled Reactors Integrated with Industrial Processes  

SciTech Connect

This report summarizes the results of a temperature sensitivity study conducted to identify the optimum reactor operating temperatures for producing the heat and hydrogen required for industrial processes associated with the proposed new high temperature gas-cooled reactor. This study assumed that primary steam outputs of the reactor were delivered at 17 MPa and 540C and the helium coolant was delivered at 7 MPa at 625925C. The secondary outputs of were electricity and hydrogen. For the power generation analysis, it was assumed that the power cycle efficiency was 66% of the maximum theoretical efficiency of the Carnot thermodynamic cycle. Hydrogen was generated via the hightemperature steam electrolysis or the steam methane reforming process. The study indicates that optimum or a range of reactor outlet temperatures could be identified to further refine the process evaluations that were developed for high temperature gas-cooled reactor-integrated production of synthetic transportation fuels, ammonia, and ammonia derivatives, oil from unconventional sources, and substitute natural gas from coal.

Lee O. Nelson

2011-04-01T23:59:59.000Z

233

PIN detector arrays and integrated readout circuitry on high-resistivity float-zone silicon  

SciTech Connect

A new silicon PIN-diode-based pixel detector for ionizing particles integrating a two-dimensional array of detecting elements with readout circuitry has been developed and extensively tested. The signal charge is collected on a low-capacitance electrode avoiding loss of charge into the local readout circuitry within each pixel. The spatial resolution for a given circuitry size is optimized. The approach required back side patterning of the wafer, the only nonconventional part in the Stanford BiCMOS based manufacturing process. Thirteen masks on the front side of the wafer and three on the back yielded both CMOS readout circuitry and detecting elements. A gettering step helped obtain a high minority carrier lifetime (500 [mu]s). Test results obtained by infrared illumination, gamma rays, and high-energy particles, which have been described in detail elsewhere, will be summarized. They include a signal to single-channel-noise performance of about 150 to 1 for a minimum ionizing particle, which is an order of magnitude better than silicon strip detectors currently used, and a record-breaking spatial resolution in the direction of smallest pixel pitch (standard deviation of about 1.8 [mu]m). The authors describe the device and chip operation of the new detector in detail.

Snoeys, W.; Plummer, J. (Stanford Univ., CA (United States). Center for Integrated Systems); Parker, S.; Kenney, C. (Univ. of Hawaii, Honolulu, HI (United States). Dept. of Physics)

1994-06-01T23:59:59.000Z

234

Design, Implementation and Performance of Exponential Integrators for High Performance Computing Applications.  

E-Print Network (OSTI)

??Exponential integrators have received renewed interest in recent years as a means to approximate stiff systems of ODEs, but are not currently widely used in (more)

Loffeld, John

2013-01-01T23:59:59.000Z

235

A high efficiency photovoltaic module integrated converter with the asymmetrical half-bridge flyback converter  

SciTech Connect

A module integrated converter (MIC) for a photovoltaic (PV) cell is important part of power conditioning system (PCS). It performs maximum power point tracking of a PV cell to generate the power as much as possible from solar energy. There are several methods for connection between the PV modules and the MICs. In order to avoid partial shading effects, converter-per-module approach was proposed. The MIC that performs maximum power point tracking (MPPT), if it is low efficiency, is no use. The MIC whose output is connected to the output of PV module was proposed for high efficiency. However, there are some problems. In this study, an asymmetrical half-bridge flyback converter is proposed instead of the original flyback converter with same method to solve the problems. The proposed MIC was built to verify the performance. The new topology using soft switching technique showed good performance for the efficiency. At the higher power, the efficiency of the proposed converter is higher than existing converter. (author)

Kim, Heeje; Kim, Jongrak; Shin, Dongsul [Department of Electrical Engineering, Pusan National University, Jangjeon, Geumjeong, Busan 609-735 (Korea); Kim, Hosung; Lee, Kyungjun [Department of Electrical Engineering, Pusan National University, Jangjeon, Geumjeong, Busan 609-735 (Korea); New and Renewable Energy System Research Center, Korea Electro-technology Research Institute, 28-1, Sungju-dong Changwon-si, Kyungsannam-do, 641-120 (Korea); Kim, Jonghyun; Yoo, Dongwook [New and Renewable Energy System Research Center, Korea Electro-technology Research Institute, 28-1, Sungju-dong Changwon-si, Kyungsannam-do, 641-120 (Korea)

2010-08-15T23:59:59.000Z

236

Temperature effect of the integral flux of cosmic-ray muons at high energies  

Science Journals Connector (OSTI)

The temperature coefficients of the integral fluxes of cosmic-ray muons arriving at sea level vertically and horizontally with energies of 102, 104, and 3 106...GeV are calculated. Decays of pions, kaons, and c...

L. V. Volkova

2013-11-01T23:59:59.000Z

237

Approaches To Integrating A HIgh Penertration Of Solar PV and CPV Onto The Electrical Grid  

E-Print Network (OSTI)

WorkshoponRenewableEnergyCostsforthe2012Integratedrenewable portfolio standards (RPS) and energy efficiency goals in a costcost of installing rooftop solar panels. While the renewable energy

Hill, Steven Craig

2013-01-01T23:59:59.000Z

238

Container throughput estimation leveraging ship GPS traces and open data  

Science Journals Connector (OSTI)

Traditionally, the port container throughput, a crucial measurement of regional economic development, was manually collected by port authorities. This requires a large amount of human effort and often delays publication of this important figure. In this ... Keywords: AIS trace, container throughput estimation, open data

Longbiao Chen, Daqing Zhang, Gang Pan, Leye Wang, Xiaojuan Ma, Chao Chen, Shijian Li

2014-09-01T23:59:59.000Z

239

Method and apparatus for maximizing throughput of indirectly heated rotary kilns  

DOE Patents (OSTI)

An apparatus and method for achieving improved throughput capacity of indirectly heated rotary kilns used to produce pyrolysis products such as shale oils or coal oils that are susceptible to decomposition by high kiln wall temperatures is disclosed. High throughput is achieved by firing the kiln such that optimum wall temperatures are maintained beginning at the point where the materials enter the heating section of the kiln and extending to the point where the materials leave the heated section. Multiple high velocity burners are arranged such that combustion products directly impact on the area of the kiln wall covered internally by the solid material being heated. Firing rates for the burners are controlled to maintain optimum wall temperatures.

Coates, Ralph L; Smoot, L. Douglas; Hatfield, Kent E

2012-10-30T23:59:59.000Z

240

Cycle time versus throughput analysis: an overall framework for generating simulation-based cycle time-throughput curves  

Science Journals Connector (OSTI)

A simulation-based cycle time-throughput curve requires a large amount of simulation output data, and an experimentation framework is needed to enhance the precision and accuracy of a simulation-based cycle time-throughput curve. In this research, approaches ...

Sungmin Park; Gerald T. Mackulak; John W. Fowler

2001-12-01T23:59:59.000Z

Note: This page contains sample records for the topic "integrated high throughput" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


241

NREL/SCE High-Penetration PV Integration Project: Report on Field Demonstration of Advanced Inverter Functionality in Fontana, CA  

SciTech Connect

The National Renewable Energy Laboratory/Southern California Edison High-Penetration PV Integration Project is (1) researching the distribution system level impacts of high-penetration photovoltaic (PV) integration, (2) determining mitigation methods to reduce or eliminate those impacts, and (3) seeking to demonstrate these mitigation methods on actual high-penetration PV distribution circuits. This report describes a field demonstration completed during the fall of 2013 on the Fontana, California, study circuit, which includes a total of 4.5 MW of interconnected utility-scale rooftop PV systems. The demonstration included operating a 2-MW PV system at an off-unity power factor that had been determined during previously completed distribution system modeling and PV impact assessment analyses. Data on the distribution circuit and PV system operations were collected during the 2-week demonstration period. This demonstration reinforces the findings of previous laboratory testing that showed that utility-scale PV inverters are capable of operating at off-unity power factor to mitigate PV impacts; however, because of difficulties setting and retaining PV inverter power factor set points during the field demonstration, it was not possible to demonstrate the effectiveness of off-unity power factor operation to mitigate the voltage impacts of high-penetration PV integration. Lessons learned from this field demonstration are presented to inform future field demonstration efforts.

Mather, B.

2014-08-01T23:59:59.000Z

242

Critical Causes of Degradation in Integrated Laboratory Scale Cells during High Temperature Electrolysis  

SciTech Connect

An ongoing project at Idaho National Laboratory involves generating hydrogen from steam using solid oxide electrolysis cells (SOEC). This report describes background information about SOECs, the Integrated Laboratory Scale (ILS) testing of solid-oxide electrolysis stacks, ILS performance degradation, and post-test examination of SOECs by various researchers. The ILS test was a 720- cell, three-module test comprised of 12 stacks of 60 cells each. A peak H2 production rate of 5.7 Nm3/hr was achieved. Initially, the module area-specific resistance ranged from 1.25 Ocm2 to just over 2 Ocm2. Total H2 production rate decreased from 5.7 Nm3/hr to a steady state value of 0.7 Nm3/hr. The decrease was primarily due to cell degradation. Post test examination by Ceramatec showed that the hydrogen electrode appeared to be in good condition. The oxygen evolution electrode does show delamination in operation and an apparent foreign layer deposited at the electrolyte interface. Post test examination by Argonne National Laboratory showed that the O2-electrode delaminated from the electrolyte near the edge. One possible reason for this delamination is excessive pressure buildup with high O2 flow in the over-sintered region. According to post test examination at the Massachusetts Institute of Technology, the electrochemical reactions have been recognized as one of the prevalent causes of their degradation. Specifically, two important degradation mechanisms were examined: (1) transport of Crcontaining species from steel interconnects into the oxygen electrode and LSC bond layers in SOECs, and (2) cation segregation and phase separation in the bond layer. INL conducted a workshop October 27, 2008 to discuss possible causes of degradation in a SOEC stack. Generally, it was agreed that the following are major degradation issues relating to SOECs: Delamination of the O2-electrode and bond layer on the steam/O2-electrode side Contaminants (Ni, Cr, Si, etc.) on reaction sites (triple phase boundary) Loss of electrical/ionic conductivity of electrolyte.

M.S. Sohal; J.E. O'Brien; C.M. Stoots; J. J. Hartvigsen; D. Larsen; S. Elangovan; J.S. Herring; J.D. Carter; V.I. Sharma; B. Yildiz

2009-05-01T23:59:59.000Z

243

Integrated High-Level Waste System Planning - Utilizing an Integrated Systems Planning Approach to Ensure End-State Definitions are Met and Executed - 13244  

SciTech Connect

The Savannah River Site (SRS) is a Department of Energy site which has produced nuclear materials for national defense, research, space, and medical programs since the 1950's. As a by-product of this activity, approximately 37 million gallons of high-level liquid waste containing approximately 292 million curies of radioactivity is stored on an interim basis in 45 underground storage tanks. Originally, 51 tanks were constructed and utilized to support the mission. Four tanks have been closed and taken out of service and two are currently undergoing the closure process. The Liquid Waste System is a highly integrated operation involving safely storing liquid waste in underground storage tanks; removing, treating, and dispositioning the low-level waste fraction in grout; vitrifying the higher activity waste at the Defense Waste Processing Facility; and storing the vitrified waste in stainless steel canisters until permanent disposition. After waste removal and processing, the storage and processing facilities are decontaminated and closed. A Liquid Waste System Plan (hereinafter referred to as the Plan) was developed to integrate and document the activities required to disposition legacy and future High-Level Waste and to remove from service radioactive liquid waste tanks and facilities. It establishes and records a planning basis for waste processing in the liquid waste system through the end of the program mission. The integrated Plan which recognizes the challenges of constrained funding provides a path forward to complete the liquid waste mission within all regulatory and legal requirements. The overarching objective of the Plan is to meet all Federal Facility Agreement and Site Treatment Plan regulatory commitments on or ahead of schedule while preserving as much life cycle acceleration as possible through incorporation of numerous cost savings initiatives, elimination of non-essential scope, and deferral of other scope not on the critical path to compliance. There is currently a premium on processing and storage space in the radioactive liquid waste tank system. To enable continuation of risk reduction initiatives, the Plan establishes a processing strategy that provides tank space required to meet, or minimizes the impacts to meeting, programmatic objectives. The Plan also addresses perturbations in funding and schedule impacts. (authors)

Ling, Lawrence T. [URS-Savannah River Remediation, Savannah River Site, Building 766-H Room 2205, Aiken, SC 29808 (United States)] [URS-Savannah River Remediation, Savannah River Site, Building 766-H Room 2205, Aiken, SC 29808 (United States); Chew, David P. [URS-Savannah River Remediation, Savannah River Site, Building 766-H Room 2426, Aiken, SC 29808 (United States)] [URS-Savannah River Remediation, Savannah River Site, Building 766-H Room 2426, Aiken, SC 29808 (United States)

2013-07-01T23:59:59.000Z

244

Congestion control schemes for single and parallel TCP flows in high bandwidth-delay product networks  

E-Print Network (OSTI)

high-speed TCP proposals have been suggested to overcome the limited throughput achievable by single-flow TCP by modifying its congestion control mechanisms. In the meantime, users overcome the throughput limitations in high bandwidth-delay product...

Cho, Soohyun

2006-08-16T23:59:59.000Z

245

Integration of High Efficiency Solar Cells on Carriers for Concentrating System Applications .  

E-Print Network (OSTI)

??High efficiency multi-junction (MJ) solar cells were packaged onto receiver systems. The efficiency change of concentrator cells under continuous high intensity illumination was done. Also, (more)

Chow, Simon Ka Ming

2011-01-01T23:59:59.000Z

246

A comparison of high-order time integrators for thermal convection in rotating spherical shells.  

E-Print Network (OSTI)

of the Coriolis term with low storage requirements. The codes are validated with a known benchmark Descubrimientos, s/n, 41092 Sevilla, Spain Abstract A numerical study of several time integration methods and extrapolation formulae are considered. The use of Krylov techniques allows the implicit treatment

Sánchez, Juan

247

Integration of High-Temperature Gas-Cooled Reactors into Industrial Process Applications  

SciTech Connect

This report is a preliminary comparison of conventional and potential HTGR-integrated processesa in several common industrial areas: ? Producing electricity via a traditional power cycle ? Producing hydrogen ? Producing ammonia and ammonia-derived products, such as fertilizer ? Producing gasoline and diesel from natural gas or coal ? Producing substitute natural gas from coal, and ? Steam-assisted gravity drainage (extracting oil from tar sands).

Lee Nelson

2009-10-01T23:59:59.000Z

248

Integrating High Penetrations of Solar in the Western United States: Results of the Western Wind and Solar Integration Study Phase 2 (Poster)  

SciTech Connect

This poster presents a summary of the results of the Western Wind and Solar Integration Study Phase 2.

Bird, L.; Lew, D.

2013-10-01T23:59:59.000Z

249

An integrated video- and weight-monitoring system for the surveillance of highly enriched uranium blend down operations  

SciTech Connect

An integrated video-surveillance and weight-monitoring system has been designed and constructed for tracking the blending down of weapons-grade uranium by the US Department of Energy. The instrumentation is being used by the International Atomic Energy Agency in its task of tracking and verifying the blended material at the Portsmouth Gaseous Diffusion Plant, Portsmouth, Ohio. The weight instrumentation developed at the Oak Ridge National Laboratory monitors and records the weight of cylinders of the highly enriched uranium as their contents are fed into the blending facility while the video equipment provided by Sandia National Laboratory records periodic and event triggered images of the blending area. A secure data network between the scales, cameras, and computers insures data integrity and eliminates the possibility of tampering. The details of the weight monitoring instrumentation, video- and weight-system interaction, and the secure data network is discussed.

Lenarduzzi, R.; Castleberry, K. [Oak Ridge National Lab., TN (United States); Whitaker, M. [Lockheed Martin Energy Systems, Oak Ridge, TN (United States); Martinez, R. [Sandia National Labs., Albuquerque, NM (United States)

1998-11-01T23:59:59.000Z

250

Throughput-cost analysis of optical flow switching  

E-Print Network (OSTI)

In this paper, we employ a cost model embodying major sources of capital expenditure (CapEx) to compare the throughput-cost tradeoff offered by optical flow switching to that of more traditional optical network architectures.

Chan, Vincent W. S.

251

Throughput-Cost Analysis of Optical Flow Switching  

Science Journals Connector (OSTI)

In this paper, we employ a cost model embodying major sources of capital expenditure (CapEx) to compare the throughput-cost tradeoff offered by Optical Flow Switching to that of more...

Weichenberg, Guy; Chan, Vincent W; Swanson, Eric A; Mdard, Muriel

252

The role of SEA in integrating and balancing high policy objectives in European cohesion funding programmes  

SciTech Connect

Funding programmes for European cohesion policy are a crucial tool to support the sustainability goals of the European Union and national policies of its member states. All these funding programmes require a Strategic Environmental Assessment (SEA) to enhance sustainable development. This article compares five first SEA applications at cohesion policy level to discuss challenges, limitations and benefits of this instrument. In order to support the SEA-process a 'Handbook on SEA for Cohesion Policy 2007-13' (GRDP 2006) was developed. The paper examines the special requirements and challenges at the programme level given the special conditions for stakeholder involvement, integration of SEA in the programme development process and strategies to cope with uncertainties to ensure real compatibility with policy goals. Using action research and in-depth interviews with SEA planners and programme managers enabled us to analyse the suitability of the methodology proposed by the handbook. The results show that some recommendations of the handbook should be changed in order to increase the transparency and to enhance the standard and comparability of the SEA-documents. Overall the SEA proved to be a rather successful tool for the integration of sustainability goals at the EU and national policy levels. Its particular strengths emerged as the process makes uncertainties visible and leads to possible redefinitions while maintaining actual policy goals. - Highlights: Black-Right-Pointing-Pointer Comparing five case studies of first applications of SEA at cohesion policy level. Black-Right-Pointing-Pointer Overall the SEA proved to be a rather successful tool for the integration of sustainability goals. Black-Right-Pointing-Pointer The study makes uncertainties visible and shows how SEA could lead to possible redefinitions.

Jiricka, Alexandra, E-mail: alexandra.jiricka@boku.ac.at; Proebstl, Ulrike, E-mail: ulrike.proebstl@boku.ac.at

2013-01-15T23:59:59.000Z

253

Computational tools for high-throughput discovery in biology  

E-Print Network (OSTI)

Towards creating a compute power grid. Cluster Computing andfor all data processing: the power grid. With a well-frameddevelopers. Since this Power Grid analogy has more or less

Jones, Neil Christopher

2007-01-01T23:59:59.000Z

254

High-Throughput Detection of West Nile Virus RNA  

Science Journals Connector (OSTI)

...increased the amplification efficiency. However, we found...increase the amplification efficiency in assays targeting...Forster Zwischenmolekulare energy-wanderung und fluoreszenz...France . J. R. Lakowicz Energy transfer . R. S. Lanciotti...Isolation from human sera in Egypt of a virus apparently...

Pei-Yong Shi; Elizabeth B. Kauffman; Ping Ren; Andy Felton; Jennifer H. Tai; Alan P. Dupuis II; Susan A. Jones; Kiet A. Ngo; David C. Nicholas; Joseph Maffei; Gregory D. Ebel; Kristen A. Bernard; Laura D. Kramer

2001-04-01T23:59:59.000Z

255

High Throughput Combinatorial Screening of Biometic Metal-Organic...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

O O OH O HO OH O Co V 3+ Cr 3+ Mn 2+ Fe 2+ Co 2+ Ni 2+ Cu 2+ Ni Pd Pt SBU metal ions bare metal Carboxylate linkers Vibrational Spectroscopy of Hydrogen Raman *H 2 in gas...

256

High-Throughput and Combinatorial Screening of Hydrogen Storage...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

method The sintering technique is used by groups at: U. Geneva (Switzerland), MPI (Germany), Stockholm University (Sweden), IFE (Norway), SRNL (USA), U. Tohoku, AIST (Japan)...

257

An apparatus for high throughput muscle cell experimentation  

E-Print Network (OSTI)

The cardiac ventricular muscle cell (myocyte) is a key experimental system for exploring the mechanical properties of the diseased and healthy heart. The myocyte experimental model provides a higher level of physiological ...

Garcia-Webb, Michael G. (Michael Gregory)

2006-01-01T23:59:59.000Z

258

High-Throughput Transfer Imprinting for Organic Semiconductors  

E-Print Network (OSTI)

focused infrared laser heats stamping layer(PMMA) up to glass transition temperature within very short time. And the pressure applied through the roller presses the flat mold and the pattern is imprinted on the PMMA layer. This method can imprint... with higher speed and achieved wider area of imprinting than conventional imprint method. [17] MOLD Substrate PMMA IR Roller Figure 8 Concept of roller imprinting based on focus infrared heating. 17 CHAPTER II PROBLEM STATEMENT...

Choo, Gihoon

2013-08-06T23:59:59.000Z

259

Computational tools for high-throughput discovery in biology  

E-Print Network (OSTI)

approach of a Service Oriented Architecture, where softwaredescribed as a service oriented architecture. Several ofWhile a Service Oriented Architecture (usually implemented

Jones, Neil Christopher

2007-01-01T23:59:59.000Z

260

High-throughput single-microparticle imaging flow analyzer  

Science Journals Connector (OSTI)

...using standard replica mold-ing methods (Fig. S1) (1). Our previously reported channels (2) were drawn in AutoCAD (Autodesk, Inc.). The design was printed as a photolithography transparency mask at 20,000 dots per inch (dpi). A negative photoresist...

Keisuke Goda; Ali Ayazi; Daniel R. Gossett; Jagannath Sadasivam; Cejo K. Lonappan; Elodie Sollier; Ali M. Fard; Soojung Claire Hur; Jost Adam; Coleman Murray; Chao Wang; Nora Brackbill; Dino Di Carlo; Bahram Jalali

2012-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "integrated high throughput" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


261

High-throughput methods for characterizing the immune repertoire  

E-Print Network (OSTI)

The adaptive immune system is one of the primary mediators in almost every major human disease, including infections, cancer, autoimmunity, and inflammation-based disorders. It fundamentally functions as a molecular ...

Laserson, Uri

2013-01-01T23:59:59.000Z

262

Mixing in Unbaffled High-Throughput Experimentation Reactors  

Science Journals Connector (OSTI)

Use of unbaffled vessels is essential because of the automation of the unit responsible for loading, sampling, discharging, and cleaning the vessel; such tasks are easier for a robot to perform on unbaffled vessels because material can be trapped around baffle plates, especially when viscous materials are involved. ... The impellers were painted with matte black paint to prevent reflection of incident laser radiation and also to seal the impeller surface. ...

Jonathan F. Hall; Mostafa Barigou; Mark J. H. Simmons; E. Hugh Stitt

2004-06-09T23:59:59.000Z

263

High-Throughput Mode Liquid Microjunction Surface Sampling Probe  

SciTech Connect

A simple and automated spot sampling operation mode for a liquid microjunction surface sampling probe/electrospray ionization mass spectrometry (LMJ-SSP/ESI-MS) system is reported. Prior manual and automated spot sampling methods with this probe relied on a careful, relatively slow alignment of the probe and surface distance (<20 m spacing) to form the probe-to-surface liquid microjunction critical to successful surface sampling. Moreover, sampling multiple spots required retraction of the surface from the probe and a repeat of this careful probe-to-surface distance alignment at the next sampling position. With the method described here, the probe was not positioned as close to the surface, the exact probeto-surface positioning was found to be less critical (spanning distances from about 100-300 m), and this distance was not altered during the sampling of an entire array of sample spots. With the probe positioned within the appropriate distance from the surface, the liquid microjunction was formed by letting the liquid from the sampling end of the probe extend out from the probe to the surface. This was accomplished by reducing the selfaspiration liquid flow rate of the probe to a value less than the volume flow rate pumped into the probe. When the self-aspiration rate of the probe was subsequently increased, analytes on the surface that dissolved at the liquid microjunction were aspirated back into the probe with the liquid that created the liquid microjunction and electrosprayed. Presented here are the basics of this new sampling mode, as well as data that illustrate the potential analytical capabilities of the device to conduct highthroughput quantitative analysis.

Van Berkel, Gary J [ORNL; Kertesz, Vilmos [ORNL; King, Richard C. [PharmaCadence

2009-01-01T23:59:59.000Z

264

Constant pressure high throughput membrane permeation testing system  

DOE Patents (OSTI)

The disclosure relates to a membrane testing system for individual evaluation of a plurality of planar membranes subjected to a feed gas on one side and a sweep gas on a second side. The membrane testing system provides a pressurized flow of a feed and sweep gas to each membrane testing cell in a plurality of membrane testing cells while a stream of retentate gas from each membrane testing cell is ported by a retentate multiport valve for sampling or venting, and a stream of permeate gas from each membrane testing cell is ported by a permeate multiport valve for sampling or venting. Back pressure regulators and mass flow controllers act to maintain substantially equivalent gas pressures and flow rates on each side of the planar membrane throughout a sampling cycle. A digital controller may be utilized to position the retentate and permeate multiport valves cyclically, allowing for gas sampling of different membrane cells over an extended period of time.

Albenze, Erik J.; Hopkinson, David P.; Luebke, David R.

2014-09-02T23:59:59.000Z

265

Operational streamlining in a high-throughput genome sequencing center  

E-Print Network (OSTI)

Advances in medicine rely on accurate data that is rapidly provided. It is therefore critical for the Genome Sequencing platform of the Broad Institute of MIT and Harvard to continually strive to reduce cost, improve ...

Person, Kerry P. (Kerry Patrick)

2006-01-01T23:59:59.000Z

266

METHODOLOGY Open Access High throughput quantitative phenotyping of  

E-Print Network (OSTI)

is not sensitive to environmental light variations and provides single-channel images prone to a segmentation Horticulture et Semences, Beaucouzé F-49071, France 2 UMR1345 Institut de Recherche en Horticulture et Semences

Paris-Sud XI, Université de

267

High Throughput/Combinatorial Screening of Hydrogen Storage Materials (presentation)  

Energy.gov (U.S. Department of Energy (DOE))

Presented at the U.S. Department of Energy's Hydrogen Storage Meeting held June 26, 2007 in Bethesda, Maryland.

268

High-throughput liquid-absorption preconcentrator sampling methods  

DOE Patents (OSTI)

A system for detecting trace concentrations of an analyte in air includes a preconcentrator for the analyte and an analyte detector. The preconcentrator includes an elongated tubular container comprising a wettable material. The wettable material is continuously wetted with an analyte-sorbing liquid which flows from one part of the container to a lower end. Sampled air flows through the container in contact with the wetted material with a swirling motion which results in efficient transfer of analyte vapors or aerosol particles to the sorbing liquid and preconcentration of traces of analyte in the liquid. The preconcentrated traces of analyte may be either detected within the container or removed therefrom for injection into a separate detection means or for subsequent analysis. 12 figs.

Zaromb, S.

1994-07-12T23:59:59.000Z

269

Vectorized AES core for high-throughput secure environments  

E-Print Network (OSTI)

`odul D6 Campus Nord, 08034 Barcelona, Spain Phone: +34 934 017 001, Fax: +34 934 017 055 mpericas the evaluation of an encryption core capable of handling multiple data streams. The de- sign is oriented towards cryptographic engines with multiple streams to better exploit the available bandwidth. Several specific cases

Kuzmanov, Georgi

270

Approaches and problems in high-throughput genotyping.  

Science Journals Connector (OSTI)

...probes; 4) DNA hybridization, e.g., microarrays, electronic DNA chips, molecular beacons, and dynamic allele-specific...Amplification. Beyond chemistries and platforms, one more fundamental thing to understand about SNP genotyping is the issue of...

Anthony J. Brookes

2004-04-01T23:59:59.000Z

271

An integrated performance model for high temperature gas cooled reactor coated particle fuel  

E-Print Network (OSTI)

The performance of coated fuel particles is essential for the development and deployment of High Temperature Gas Reactor (HTGR) systems for future power generation. Fuel performance modeling is indispensable for understanding ...

Wang, Jing, 1976-

2004-01-01T23:59:59.000Z

272

Millimeter-wave GaN high electron mobility transistors and their integration with silicon electronics  

E-Print Network (OSTI)

In spite of the great progress in performance achieved during the last few years, GaN high electron mobility transistors (HEMTs) still have several important issues to be solved for millimeter-wave (30 ~ 300 GHz) applications. ...

Chung, Jinwook W. (Jinwook Will)

2011-01-01T23:59:59.000Z

273

Policies and Programs to Integrate High Penetrations of Variable Renewable Energy (Presentation)  

SciTech Connect

The goals of this project are to highlight the diverse approaches for enabling high renewable energy penetration; synthesize lessons on effective policies and programs and present avenues for action to energy ministers and other stakeholders.

Cochran, J.

2012-06-01T23:59:59.000Z

274

Integrated Remediation Process for a High Salinity Industrial Soil Sample Contaminated with Heavy Oil and Metals  

Science Journals Connector (OSTI)

A highly saline industrial soil sample contaminated with heavy oils and several heavy metals, was tested for remediation using NRCs Solvent Extraction Soil Remediation (SESR) process. The sample was provided ...

Abdul Majid; Bryan D. Sparks

2002-01-01T23:59:59.000Z

275

Approaches To Integrating A HIgh Penertration Of Solar PV and CPV Onto The Electrical Grid  

E-Print Network (OSTI)

problems are encountered. There are utility concerns that a high penetration of inverter-based solar energyproblem with a non-imaging 2D Fresnel concentrator. Lorenzo (1981) evaluated chromatic aberrations in solar energy

Hill, Steven Craig

2013-01-01T23:59:59.000Z

276

Passive components for dense optical integration based on high index-contrast  

E-Print Network (OSTI)

This work presents a theoretical and numerical investigation of high index-contrast passive components that can serve as building blocks at the end-pointsand nodes of WDM communications systems. The main characteristic of ...

Manolatou, Christina

2001-01-01T23:59:59.000Z

277

A One System Integrated Approach to Simulant Selection for Hanford High Level Waste Mixing and Sampling Tests  

SciTech Connect

The Hanford Tank Operations Contractor (TOC) and the Hanford Waste Treatment and Immobilization Plant (WTP) contractor are both engaged in demonstrating mixing, sampling, and transfer system capabilities using simulated Hanford High-Level Waste (HLW) formulations. This represents one of the largest remaining technical issues with the high-level waste treatment mission at Hanford. Previous testing has focused on very specific TOC or WTP test objectives and consequently the simulants were narrowly focused on those test needs. A key attribute in the Defense Nuclear Facilities Safety Board (DNFSB) Recommendation 2010-2 is to ensure testing is performed with a simulant that represents the broad spectrum of Hanford waste. The One System Integrated Project Team is a new joint TOC and WTP organization intended to ensure technical integration of specific TOC and WTP systems and testing. A new approach to simulant definition has been mutually developed that will meet both TOC and WTP test objectives for the delivery and receipt of HLW. The process used to identify critical simulant characteristics, incorporate lessons learned from previous testing, and identify specific simulant targets that ensure TOC and WTP testing addresses the broad spectrum of Hanford waste characteristics that are important to mixing, sampling, and transfer performance are described.

Thien, Mike G. [Washington River Protection Solutions, LLC, Richland, WA (United States); Barnes, Steve M. [URS, Richland, WA (United States)

2013-01-17T23:59:59.000Z

278

A One System Integrated Approach to Simulant Selection for Hanford High Level Waste Mixing and Sampling Tests - 13342  

SciTech Connect

The Hanford Tank Operations Contractor (TOC) and the Hanford Waste Treatment and Immobilization Plant (WTP) contractor are both engaged in demonstrating mixing, sampling, and transfer system capabilities using simulated Hanford High-Level Waste (HLW) formulations. This represents one of the largest remaining technical issues with the high-level waste treatment mission at Hanford. Previous testing has focused on very specific TOC or WTP test objectives and consequently the simulants were narrowly focused on those test needs. A key attribute in the Defense Nuclear Facilities Safety Board (DNFSB) Recommendation 2010-2 is to ensure testing is performed with a simulant that represents the broad spectrum of Hanford waste. The One System Integrated Project Team is a new joint TOC and WTP organization intended to ensure technical integration of specific TOC and WTP systems and testing. A new approach to simulant definition has been mutually developed that will meet both TOC and WTP test objectives for the delivery and receipt of HLW. The process used to identify critical simulant characteristics, incorporate lessons learned from previous testing, and identify specific simulant targets that ensure TOC and WTP testing addresses the broad spectrum of Hanford waste characteristics that are important to mixing, sampling, and transfer performance are described. (authors)

Thien, Mike G. [Washington River Protection Solutions, LLC, P.O Box 850, Richland WA, 99352 (United States)] [Washington River Protection Solutions, LLC, P.O Box 850, Richland WA, 99352 (United States); Barnes, Steve M. [Waste Treatment Plant, 2435 Stevens Center Place, Richland WA 99354 (United States)] [Waste Treatment Plant, 2435 Stevens Center Place, Richland WA 99354 (United States)

2013-07-01T23:59:59.000Z

279

Integrated Process Configuration for High-Temperature Sulfur Mitigation during Biomass Conversion via Indirect Gasification  

SciTech Connect

Sulfur present in biomass often causes catalyst deactivation during downstream operations after gasification. Early removal of sulfur from the syngas stream post-gasification is possible via process rearrangements and can be beneficial for maintaining a low-sulfur environment for all downstream operations. High-temperature sulfur sorbents have superior performance and capacity under drier syngas conditions. The reconfigured process discussed in this paper is comprised of indirect biomass gasification using dry recycled gas from downstream operations, which produces a drier syngas stream and, consequently, more-efficient sulfur removal at high temperatures using regenerable sorbents. A combination of experimental results from NREL's fluidizable Ni-based reforming catalyst, fluidizable Mn-based sulfur sorbent, and process modeling information show that using a coupled process of dry gasification with high-temperature sulfur removal can improve the performance of Ni-based reforming catalysts significantly.

Dutta. A.; Cheah, S.; Bain, R.; Feik, C.; Magrini-Bair, K.; Phillips, S.

2012-06-20T23:59:59.000Z

280

Integration of highly probabilistic sources into optical quantum architectures: perpetual quantum computation  

E-Print Network (OSTI)

In this paper we introduce a design for an optical topological cluster state computer constructed exclusively from a single quantum component. Unlike previous efforts we eliminate the need for on demand, high fidelity photon sources and detectors and replace them with the same device utilised to create photon/photon entanglement. This introduces highly probabilistic elements into the optical architecture while maintaining complete specificity of the structure and operation for a large scale computer. Photons in this system are continually recycled back into the preparation network, allowing for a arbitrarily deep 3D cluster to be prepared using a comparatively small number of photonic qubits and consequently the elimination of high frequency, deterministic photon sources.

Simon J. Devitt; Ashley M. Stephens; William J. Munro; Kae Nemoto

2011-02-02T23:59:59.000Z

Note: This page contains sample records for the topic "integrated high throughput" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


281

A high-resolution integrated model of the National Ignition Campaign cryogenic layered experiments  

SciTech Connect

A detailed simulation-based model of the June 2011 National Ignition Campaign cryogenic DT experiments is presented. The model is based on integrated hohlraum-capsule simulations that utilize the best available models for the hohlraum wall, ablator, and DT equations of state and opacities. The calculated radiation drive was adjusted by changing the input laser power to match the experimentally measured shock speeds, shock merger times, peak implosion velocity, and bangtime. The crossbeam energy transfer model was tuned to match the measured time-dependent symmetry. Mid-mode mix was included by directly modeling the ablator and ice surface perturbations up to mode 60. Simulated experimental values were extracted from the simulation and compared against the experiment. Although by design the model is able to reproduce the 1D in-flight implosion parameters and low-mode asymmetries, it is not able to accurately predict the measured and inferred stagnation properties and levels of mix. In particular, the measured yields were 15%-40% of the calculated yields, and the inferred stagnation pressure is about 3 times lower than simulated.

Jones, O. S.; Cerjan, C. J.; Marinak, M. M.; Milovich, J. L.; Robey, H. F.; Springer, P. T.; Benedetti, L. R.; Bleuel, D. L.; Bond, E. J.; Bradley, D. K.; Callahan, D. A.; Caggiano, J. A.; Celliers, P. M.; Clark, D. S.; Dixit, S. M.; Doppner, T.; Dylla-Spears, R. J.; Dzentitis, E. G.; Farley, D. R.; Glenn, S. M. [Lawrence Livermore National Laboratory, 7000 East Avenue, L-399, Livermore, California 94551 (United States); and others

2012-05-15T23:59:59.000Z

282

Cost Effective, High Efficiency Integrated Systems Approach To Auxiliary Electric Motors  

SciTech Connect

The CARAT program, carried out by Kinetic Art & Technology Corporation (KAT), has been one of the most commercially successful KAT R&D programs to date. Based on previous development of its technology, KAT designed, constructed and tested a highly efficient motor and controller system under this CARAT program with supplemental commercial funding. Throughout this CARAT effort, the technical objectives have been refined and refocused. Some objectives have been greatly expanded, while others have been minimized. The determining factor in all decisions to refocus the objectives was the commercial need, primarily the needs of KAT manufacturing partners. Several companies are employing the resulting CARAT motor and controller designs in prototypes for commercial products. Two of these companies have committed to providing cost share in order to facilitate the development. One of these companies is a major manufacturing company developing a revolutionary new family of products requiring the ultra-high system efficiency achievable by the KAT motor and controller technologies (known as Segmented ElectroMagnetic Array, or SEMA technology). Another company requires the high efficiency, quiet operation, and control characteristics afforded by the same basic motor and controller for an advanced air filtration product. The combined annual production requirement projected by these two companies exceeds one million units by 2005.

Roy Kessinger; Kanchan Angal; Steve Brewer; Steve Kraihanzel; Lenny Schrank; Jason Wolf

2003-07-15T23:59:59.000Z

283

Cost Effective, High Efficiency Integrated Systems Approach to Auxilliary Electric Motors  

SciTech Connect

The CARAT program, carried out by Kinetic Art & Technology Corporation (KAT), has been one of the most commercially successful KAT R&D programs to date. Based on previous development of its technology, KAT designed, constructed and tested a highly efficient motor and controller system under this CARAT program with supplemental commercial funding. Throughout this CARAT effort, the technical objectives have been refined and refocused. Some objectives have been greatly expanded, while others have been minimized. The determining factor in all decisions to refocus the objectives was the commercial need, primarily the needs of KAT manufacturing partners. Several companies are employing the resulting CARAT motor and controller designs in prototypes for commercial products. Two of these companies have committed to providing cost share in order to facilitate the development. One of these companies is a major manufacturing company developing a revolutionary new family of products requiring the ultra-high system efficiency achievable by the KAT motor and controller technologies (known as Segmented ElectroMagnetic Array, or SEMA technology). Another company requires the high efficiency, quiet operation, and control characteristics afforded by the same basic motor and controller for an advanced air filtration product. The combined annual production requirement projected by these two companies exceeds one million units by 2005.

Roy Kessinger Jr.; Keith Seymour; Kanchan Angal; Jason Wolf; Steve Brewer; Leonard Schrank

2003-09-26T23:59:59.000Z

284

Maglev vehicles and superconductor technology: Integration of high-speed ground transportation into the air travel system  

SciTech Connect

This study was undertaken to (1) evaluate the potential contribution of high-temperature superconductors (HTSCs) to the technical and economic feasibility of magnetically levitated (maglev) vehicles, (2) determine the status of maglev transportation research in the United States and abroad, (3) identify the likelihood of a significant transportation market for high-speed maglev vehicles, and (4) provide a preliminary assessment of the potential energy and economic benefits of maglev systems. HTSCs should be considered as an enhancing, rather than an enabling, development for maglev transportation because they should improve reliability and reduce energy and maintenance costs. Superconducting maglev transportation technologies were developed in the United States in the late 1960s and early 1970s. Federal support was withdrawn in 1975, but major maglev transportation programs were continued in Japan and West Germany, where full-scale prototypes now carry passengers at speeds of 250 mi/h in demonstration runs. Maglev systems are generally viewed as very-high-speed train systems, but this study shows that the potential market for maglev technology as a train system, e.g., from one downtown to another, is limited. Rather, aircraft and maglev vehicles should be seen as complementing rather than competing transportation systems. If maglev systems were integrated into major hub airport operations, they could become economical in many relatively high-density US corridors. Air traffic congestion and associated noise and pollutant emissions around airports would also be reduced. 68 refs., 26 figs., 16 tabs.

Johnson, L.R.; Rote, D.M.; Hull, J.R.; Coffey, H.T.; Daley, J.G.; Giese, R.F.

1989-04-01T23:59:59.000Z

285

NREL/SCE High Penetration PV Integration Project: FY13 Annual Report  

SciTech Connect

In 2010, the National Renewable Energy Laboratory (NREL), Southern California Edison (SCE), Quanta Technology, Satcon Technology Corporation, Electrical Distribution Design (EDD), and Clean Power Research (CPR) teamed to analyze the impacts of high penetration levels of photovoltaic (PV) systems interconnected onto the SCE distribution system. This project was designed specifically to benefit from the experience that SCE and the project team would gain during the installation of 500 megawatts (MW) of utility-scale PV systems (with 1-5 MW typical ratings) starting in 2010 and completing in 2015 within SCE's service territory through a program approved by the California Public Utility Commission (CPUC). This report provides the findings of the research completed under the project to date.

Mather, B. A.; Shah, S.; Norris, B. L.; Dise, J. H.; Yu, L.; Paradis, D.; Katiraei, F.; Seguin, R.; Costyk, D.; Woyak, J.; Jung, J.; Russell, K.; Broadwater, R.

2014-06-01T23:59:59.000Z

286

High-performance broadband optical coatings on InGaN/GaN solar cells for multijunction device integration  

SciTech Connect

We demonstrate InGaN/GaN multiple quantum well solar cells grown by metalorganic chemical vapor deposition on a bulk (0001) substrate with high-performance broadband optical coatings to improve light absorption. A front-side anti-reflective coating and a back-side dichroic mirror were designed to minimize front surface reflections across a broad spectral range and maximize rear surface reflections only in the spectral range absorbed by the InGaN, making the cells suitable for multijunction solar cell integration. Application of optical coatings increased the peak external quantum efficiency by 56% (relative) and conversion efficiency by 37.5% (relative) under 1 sun AM0 equivalent illumination.

Young, N. G., E-mail: ngyoung@engineering.ucsb.edu; Farrell, R. M.; Iza, M.; Speck, J. S. [Materials Department, University of California, Santa Barbara, California 93106 (United States); Perl, E. E.; Keller, S. [Department of Electrical and Computer Engineering, University of California, Santa Barbara, California 93106 (United States); Bowers, J. E.; Nakamura, S.; DenBaars, S. P. [Materials Department, University of California, Santa Barbara, California 93106 (United States); Department of Electrical and Computer Engineering, University of California, Santa Barbara, California 93106 (United States)

2014-04-21T23:59:59.000Z

287

Disposal demonstration of a high integrity container (HIC) containing an EPICOR-II prefilter from Three Mile Island  

SciTech Connect

A high integrity container (HIC) was developed, tested, and certified for use in disposing of unusual low-level radioactive waste from Three Mile Island Unit 2 (TMI-2). The work was coordinated by EG and G Idaho, Inc. and funded by the US Department of Energy. A disposal demonstration using an HIC containing an EPICOR-II prefilter from TMI-2 was completed at the commercial disposal facility in the State of Washington. A Certification of Compliance was issued by the Department of Social and Health Services of the State of Washington to use the HIC in disposing of up to 50 EPICOR-II prefilters. That Certification of Compliance was issued after rigorous review of the HIC design and test program by the State and by the US Nuclear Regulatory Commission. This report describes the processes of loading, transporting, and disposing of the demonstration HIC and briefly describes the design, testing, and approval effort leading up to the demonstration.

McConnell, J.W. Jr.; Tyacke, M.J.; Schmitt, R.C.; Reno, H.W.

1985-02-01T23:59:59.000Z

288

Throughput Enhancing Cooperative Spectrum Sensing Strategies for Cognitive Radios  

E-Print Network (OSTI)

Throughput Enhancing Cooperative Spectrum Sensing Strategies for Cognitive Radios Kyounghwan Lee growth of wireless services continues to accelerate the exhaustion of usable radio spectrum. The radio channels licensed to the primary users. A main chal- lenge in this case is to design a spectrum sensing

Yener, Aylin

289

Optimizing Throughput and Energy in Online Deadline Scheduling  

E-Print Network (OSTI)

of all jobs. An optimal schedule is expected to maximize the throughput, and furthermore, its energy a scheduling algorithm, one has to face the dilemma of selecting more jobs and being conservative in energy jobs; O(1)-competitive online algorithms with respect to energy usage have been known [Yao et al. 1995

Wong, Prudence W.H.

290

Applying Speculative Technique to Improve TCP Throughput over Lossy Links  

E-Print Network (OSTI)

, Mohammed Atiquzzaman Honeywell Labs 3660 Technology Drive Minneapolis, MN 55418, USA E-mail: haowei.bai@honeywell #12;Applying Speculative Technique to Improve TCP Throughput over Lossy Links Haowei Bai Honeywell Labs 3660 Technology Drive Minneapolis, MN 55418 haowei.bai@honeywell.com David Lilja Electrical

Minnesota, University of

291

Dynamic Power Allocation For Maximizing Throughput in Energy Harvesting  

E-Print Network (OSTI)

1 Dynamic Power Allocation For Maximizing Throughput in Energy Harvesting Communication System general case of arbitrarily varying energy arrivals is considered, where neither the future energy arrival strategy that invests available energy uniformly over all remaining slots until the next energy arrival

Vaze, Rahul

292

Safe Overprovisioning: Using Power Limits to Increase Aggregate Throughput  

E-Print Network (OSTI)

-scalable system components allow for dynamically controlling power consumption with an accompanying ef- fect disruptions occur along with the ability to monitor aggregate power usage [4]. Hardware provides a meansSafe Overprovisioning: Using Power Limits to Increase Aggregate Throughput Mark E. Femal

Reeves, Douglas S.

293

Automatic Memory Partitioning and Scheduling for Throughput and Power Optimization  

E-Print Network (OSTI)

- matic memory partitioning technique which can efficiently improve throughput and reduce energy to tackle this problem is to increase memory ports in the final memory imple- mentations. However, recent research in [16] shows that the size of memory cells increases almost quadratically with port number N

Cong, Jason "Jingsheng"

294

Anatomy of the AGN in NGC 5548: III. The high-energy view with NuSTAR and INTEGRAL  

E-Print Network (OSTI)

We describe the analysis of the seven broad-band X-ray continuum observations of the archetypal Seyfert 1 galaxy NGC 5548 that were obtained with XMM-Newton or Chandra, simultaneously with high-energy (> 10 keV) observations with NuSTAR and INTEGRAL. These data were obtained as part of a multiwavelength campaign undertaken from the summer of 2013 till early 2014. We find evidence of a high-energy cut-off in at least one observation, which we attribute to thermal Comptonization, and a constant reflected component that is likely due to neutral material at least a few light months away from the continuum source. We confirm the presence of strong, partial covering X-ray absorption as the explanation for the sharp decrease in flux through the soft X-ray band. The obscurers appear to be variable in column density and covering fraction on time scales as short as weeks. A fit of the average spectrum over the range 0.3-400 keV with a realistic Comptonization model indicates the presence of a hot corona with a temperat...

Ursini, F; Petrucci, P -O; Matt, G; Cappi, M; Bianchi, S; Kaastra, J; Harrison, F; Walton, D J; di Gesu, L; Costantini, E; De Marco, B; Kriss, G A; Mehdipour, M; Paltani, S; Peterson, B M; Ponti, G; Steenbrugge, K C

2015-01-01T23:59:59.000Z

295

Silicon-on-insulator-based high-voltage, high-temperature integrated circuit gate driver for silicon carbide-based power field effect transistors  

SciTech Connect

Silicon carbide (SiC)-based field effect transistors (FETs) are gaining popularity as switching elements in power electronic circuits designed for high-temperature environments like hybrid electric vehicle, aircraft, well logging, geothermal power generation etc. Like any other power switches, SiC-based power devices also need gate driver circuits to interface them with the logic units. The placement of the gate driver circuit next to the power switch is optimal for minimising system complexity. Successful operation of the gate driver circuit in a harsh environment, especially with minimal or no heat sink and without liquid cooling, can increase the power-to-volume ratio as well as the power-to-weight ratio for power conversion modules such as a DC-DC converter, inverter etc. A silicon-on-insulator (SOI)-based high-voltage, high-temperature integrated circuit (IC) gate driver for SiC power FETs has been designed and fabricated using a commercially available 0.8--m, 2-poly and 3-metal bipolar-complementary metal oxide semiconductor (CMOS)-double diffused metal oxide semiconductor (DMOS) process. The prototype circuit-s maximum gate drive supply can be 40-V with peak 2.3-A sourcing/sinking current driving capability. Owing to the wide driving range, this gate driver IC can be used to drive a wide variety of SiC FET switches (both normally OFF metal oxide semiconductor field effect transistor (MOSFET) and normally ON junction field effect transistor (JFET)). The switching frequency is 20-kHz and the duty cycle can be varied from 0 to 100-. The circuit has been successfully tested with SiC power MOSFETs and JFETs without any heat sink and cooling mechanism. During these tests, SiC switches were kept at room temperature and ambient temperature of the driver circuit was increased to 200-C. The circuit underwent numerous temperature cycles with negligible performance degradation.

Tolbert, Leon M [ORNL; Huque, Mohammad A [ORNL; Blalock, Benjamin J [ORNL; Islam, Syed K [ORNL

2010-01-01T23:59:59.000Z

296

NREL Analysis: Cost-Effective and Reliable Integration of High-Penetration Solar in the Western United States (Poster)  

SciTech Connect

SunShot Initiative awardee posters describing the different technologies within the four subprograms of the DOE Solar Program (Photovoltaics, Concentrating Solar Power, Soft Costs, and Systems Integration).

Lew, D.; Brinkman, G.; Ibanez, E.; Hodge, B.; Lefton, S.; Kumar, N.; Agan, D.; Jordan, G.; Venkatataman, S.

2012-07-01T23:59:59.000Z

297

Design of all-optical high-order temporal integrators based on multiple-phase-shifted Bragg gratings  

Science Journals Connector (OSTI)

In exact analogy with their electronic counterparts, photonic temporal integrators are fundamental building blocks for constructing all-optical circuits for ultrafast information...

Asghari, Mohammad H; Azaa, Jos

2008-01-01T23:59:59.000Z

298

A flow integrated DSD hydrodynamics strategy for computing the motion of detonation of insensitive high explosives on an Eulerian grid  

SciTech Connect

The detonation structure in many insensitive high explosives consists of two temporally disparate zones of heat release. In PBX 9502, there is a fast reaction zone ({approx} 25 ns) during which reactants are converted to gaseous products and small carbon clusters, followed by a slower regime ({approx} 250 ns) of carbon coagulation. A hybrid approach for determining the propagation of two-stage heat release detonations has been developed that utilizes a detonation shock dynamics (DSD) based strategy for the fast reaction zone with a direct hydrodynamic simulation of the flow in the slow zone. Unlike a standard DSD/programmed bum formulation, the evolution of the fast zone DSD-like surface is coupled to the flow in the slow reaction zone. We have termed this formulation flow integrated detonation shock dynamics (FIDSD). The purpose of the present paper is to show how the FIDSD formulation can be applied to detonation propagation on an Eulerian grid using an algorithm based on level set interface tracking and a ghost fluid approach.

Short, Mark [Los Alamos National Laboratory; Aslam, Tariq D [Los Alamos National Laboratory

2010-01-01T23:59:59.000Z

299

Design and analysis of a high heat load pin-post monochromator crystal with an integral water manifold  

SciTech Connect

Conventional minichannel water cooling geometry will not perform satisfactorily for x-radiation from a wiggler source at the Advanced Photon Source. For closed-gap wiggler operation, cryogenic silicon appears to be the only option for crystals in Bragg-Bragg geometry. For operation of the wiggler at more modest critical energies ({lt}17 keV), the first crystal can be cooled by a pin-post cooling scheme, using water at room temperature as a coolant. In order to limit the water consumption to 4 gpm and hence the risk of introducing vibrations to the crystal, the intensely cooled area of the crystal was matched to the footprint of the beam, leaving a less cooled area of the crystal subject to survival in a missteered beam but not to perform as a monochromator. The manifold design avoids large areas of high water pressure that would bow the crystal. We present here the design of a pin-post monochromator consisting of a four-layer silicon manifold system and an integrally bonded 39{percent} nickel-iron alloy base plate. A transparent prototype of the design will be exhibited. Fabrication techniques and design advantages will be discussed. {copyright} {ital 1996 American Institute of Physics.}

Schildkamp, W. [Consortium for Advanced Radiation Sources, University of Chicago, 5640 S. Ellis Ave., Chicago, IL 60637 (United States)] [Consortium for Advanced Radiation Sources, University of Chicago, 5640 S. Ellis Ave., Chicago, IL 60637 (United States); Tonnessen, T. [Rocketdyne Albuquerque Operations, 2511 C. Broadbent Parkway, N.E., Albuquerque, NM 87107 (United States)] [Rocketdyne Albuquerque Operations, 2511 C. Broadbent Parkway, N.E., Albuquerque, NM 87107 (United States)

1996-09-01T23:59:59.000Z

300

A Review of Proposed Upgrades to the High Flux Isotope Reactor and Potential Impacts to Reactor Vessel Integrity  

SciTech Connect

The High Flux Isotope Reactor (HFIR) at Oak Ridge National Laboratory (ORNL) was scheduled in October 2000 to implement design upgrades that include the enlargement of the HB-2 and HB-4 beam tubes. Higher dose rates and higher radiation embrittlement rates were predicted for the two beam-tube nozzles and surrounding vessel areas. ORNL had performed calculations for the upgraded design to show that vessel integrity would be maintained at acceptable levels. Pacific Northwest National Laboratory (PNNL) was requested by the U.S. Department of Energy Headquarters (DOE/HQ) to perform an independent peer review of the ORNL evaluations. PNNL concluded that the calculated probabilities of failure for the HFIR vessel during hydrostatic tests and for operational conditions as estimated by ORNL are an acceptable basis for selecting pressures and test intervals for hydrostatic tests and for justifying continued operation of the vessel. While there were some uncertainties in the embrittlement predictions, the ongoing efforts at ORNL to measure fluence levels at critical locations of the vessel wall and to test materials from surveillance capsules should be effective in dealing with embrittlement uncertainties. It was recommended that ORNL continue to update their fracture mechanics calculations to reflect methods and data from ongoing research for commercial nuclear power plants. Such programs should provide improved data for vessel fracture mechanics calculations.

Simonen, Fredric A.

2001-05-31T23:59:59.000Z

Note: This page contains sample records for the topic "integrated high throughput" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


301

High-Throughput, High-Precision Hot Testing Tool for High-Brightness...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Light-Emitting Diode Testing More Documents & Publications 2014 Solid-State Lighting Project Portfolio A Practical Primer to LED Technology LED Color Characteristics...

302

Justifying Integrity Using a Virtual Machine Verifier Emerging distributing computing architectures, such as grid and cloud computing, depend on the high in-  

E-Print Network (OSTI)

architectures, such as grid and cloud computing, depend on the high in- tegrity execution of each system in distributed computing architectures. In this architecture, we strive for classical integrity, using. 1 Introduction With the emergence of a variety of distributed computing architectures, such as grid

Yener, Aylin

303

To cite this document: LASNIER Gilles, PAUTET Laurent, HUGUES Jrme. A Model-based transformation process to validate and implement high-integrity systems. In: 14th IEEE  

E-Print Network (OSTI)

process to validate and implement high-integrity systems. In: 14th IEEE International Symposium on Object-level mechanisms used. In this paper, we present our approach based on AADL and its behavioral annex to refine-critical in that their failure could result in the failure of the mission, or great damage. This particular class of systems

Mailhes, Corinne

304

Utilizing RF-I and Intelligent Scheduling for Better Throughput/Watt in a Mobile GPU Memory System  

E-Print Network (OSTI)

Utilizing RF-I and Intelligent Scheduling for Better Throughput/Watt in a Mobile GPU Memory System system is essential for the mobile GPU. In this article, we propose to improve throughput/watt are able to improve throughput 17% up to 66% while increasing throughput per watt by an average of 18% up

Cong, Jason "Jingsheng"

305

PRECISE THROUGHPUT DETERMINATION OF THE PanSTARRS TELESCOPE AND THE GIGAPIXEL IMAGER USING A CALIBRATED SILICON PHOTODIODE AND A TUNABLE LASER: INITIAL RESULTS  

SciTech Connect

We have used a precision-calibrated photodiode as the fundamental metrology reference in order to determine the relative throughput of the PanSTARRS telescope and the Gigapixel imager, from 400 nm to 1050 nm. Our technique uses a tunable laser as a source of illumination on a transmissive flat-field screen. We determine the full-aperture system throughput as a function of wavelength, including (in a single integral measurement) the mirror reflectivity, the transmission functions of the filters and the corrector optics, and the detector quantum efficiency, by comparing the light seen by each pixel in the CCD array to that measured by a precision-calibrated silicon photodiode. This method allows us to determine the relative throughput of the entire system as a function of wavelength, for each pixel in the instrument, without observations of celestial standards. We present promising initial results from this characterization of the PanSTARRS system, and we use synthetic photometry to assess the photometric perturbations due to throughput variation across the field of view.

Stubbs, Christopher W.; Doherty, Peter; Cramer, Claire; Narayan, Gautham; Brown, Yorke J. [Department of Physics, 17 Oxford Street Harvard University, Cambridge MA 02138 (United States); Lykke, Keith R.; Woodward, John T. [National Institute of Standards and Technology, 100 Bureau Drive, Gaithersburg MD 20899 (United States); Tonry, John L., E-mail: stubbs@physics.harvard.ed [Institute for Astronomy, University of Hawaii, 2680 Woodlawn Drive, Honolulu HI 96822 (United States)

2010-12-15T23:59:59.000Z

306

How Do High Levels of Wind and Solar Impact the Grid? The Western Wind and Solar Integration Study  

SciTech Connect

This paper is a brief introduction to the scope of the Western Wind and Solar Integration Study (WWSIS), inputs and scenario development, and the key findings of the study.

Lew, D.; Piwko, D.; Miller, N.; Jordan, G.; Clark, K.; Freeman, L.

2010-12-01T23:59:59.000Z

307

Power Integrations Inc | Open Energy Information  

Open Energy Info (EERE)

Integrations Inc Jump to: navigation, search Name: Power Integrations Inc Place: San Jose, California Zip: 95138 Product: Supplier of high-voltage analog integrated circuits used...

308

Integrated X-Ray Reflectivity Measurements for Elliptically Curved PET Crystals  

SciTech Connect

Spectroscopy provides valuable information about the temperature and density of a compressed pellet in a plasma. Elliptically curved pentaerythritol (PET) crystals are used as components for spectrometers. Their elliptical geometry gives several advantages related to spectral energy range, source focus, and spectral image compression.[1] The crystal curvature increases the spectrometer throughput but at the cost of a loss in resolution. Four different crystals are used in a spectrometer at the National Ignition Facility (NIF) target chamber at Lawrence Livermore National Laboratory (LLNL). Figure 1 shows the arrangement of the elliptical PET crystals in the snout of a NIF target diagnostic shown in Figure 2. The spectrum from the crystals is captured by four image plates located behind the crystals. A typical mandrel, the darkened section, upon which the PET crystal is glued, is shown in Figure 3, which also shows the complete ellipse. There are four elliptical segment types, each having the same major axis but a different minor axis. The crystals are 150 mm long in the diffraction direction and 25.4 mm high. Two crystals of each type were calibrated. The throughput for each spectrometer is determined by the integrated reflectivity of the PET crystal.[1] The goal of this effort was to measure the reflectivity curve of the PET curved crystal at several energies and determine the integrated reflectivity and the curve width as a function of the X-ray spectral energy and location on the ellipse where the beam strikes.

Haugh, M J; Ross, P W; Regan, P W; Magoon, J; Shoup, M J; Barrios, M A; Emig, J A

2012-04-26T23:59:59.000Z

309

Integrated System  

NLE Websites -- All DOE Office Websites (Extended Search)

Integrated Window System Our research activities in the field of high performance windows have led us to conclude that even by using high performance insulating glass units, low conductivity frames, and warm edge spacers, there are still untapped sources for improving energy efficiency in the design and use of residential windows. While such high performance windows are a dramatic improvement over conventional units, they do not reduce conductive losses through wall framing around the window, offer guarantees against excessive wall/window infiltration nor do they adapt to the daily and seasonal potentials for night insulation and summer shading. To meet this need, we have been working on the design, development, and prototyping of Integrated Window Systems (IWS) since 1993. Integrated Window Systems are a form of panelized construction where the wall panel includes an operable or fixed window sash, recessed night insulation, integral solar shading, and is built in a factory setting in order to minimize thermal short circuits and infiltration at joints. IWSs can be built in modular lengths to facilitate their installation with conventional wood frame stick construction or other forms of panelized construction.

310

INEX (integrated numerical experiment) simulations of the Los Alamos HIBAF (high-brightness accelerator free-electron laser) free-electron laser MOPA (master oscillator power amplifier) experiment  

SciTech Connect

We present results of Integrated Numerical Experiment (INEX) simulations of the performance of a 1-m untapered wiggler FEL oscillator driving a 2-m wiggler FEL amplifier for the new HIBAF (High-Brightness Accelerator Free-Electron Laser) facility at Los Alamos. INEX simulations utilize a numerically-generated electron micropulse, from ISIS/PARMELA calculations of the photoinjector/linac/beam transport system, in the 3-D FEL simulation code FELEX. 13 refs., 10 figs., 1 tab.

Goldstein, J.C.; Carlsten, B.E.; McVey, B.D.

1989-01-01T23:59:59.000Z

311

Throughput Measurement of a Multilayer-Coated Schwarzschild Objective Using Synchrotron Radiation  

Science Journals Connector (OSTI)

The throughput of a Schwarzschild objective using undulator synchrotron radiation was measured. ... estimated from the squared reflectivity of one multilayer mirror and from the obstruction ratio. However,...

Takanori Kiyokura; Fumihiko MAEDA; Yoshio Watanabe; Yoshinori Iketaki

312

IAS15: a fast, adaptive, high-order integrator for gravitational dynamics, accurate to machine precision over a billion orbits  

Science Journals Connector (OSTI)

......error behaves like a random walk. Our tests show that ias15 is superior to a mixed-variable...that ias15 follows Brouwer's law. We test our integrator in a wide variety of cases...focus on the two-body problem, a simple test case where we know the correct answer......

Hanno Rein; David S. Spiegel

2015-01-01T23:59:59.000Z

313

Hazardous Waste/Mixed Waste Treatment Building throughput study  

SciTech Connect

The hazardous waste/mixed waste HW/MW Treatment Building (TB) is the specified treatment location for solid hazardous waste/mixed waste at SRS. This report provides throughput information on the facility based on known and projected waste generation rates. The HW/MW TB will have an annual waste input for the first four years of approximately 38,000 ft{sup 3} and have an annual treated waste output of approximately 50,000 ft{sup 3}. After the first four years of operation it will have an annual waste input of approximately 16,000 ft{sup 3} and an annual waste output of approximately 18,000 ft. There are several waste streams that cannot be accurately predicted (e.g. environmental restoration, decommissioning, and decontamination). The equipment and process area sizing for the initial four years should allow excess processing capability for these poorly defined waste streams. A treatment process description and process flow of the waste is included to aid in understanding the computations of the throughput. A description of the treated wastes is also included.

England, J.L.; Kanzleiter, J.P.

1991-12-18T23:59:59.000Z

314

Integrated LED Headlamp Module  

Science Journals Connector (OSTI)

LED headlamp module integrates all necessary optics, electronics, and heat management into one compact unit that fits into standard mechanical headlamp frame. It provides high beam,...

Popelek, Jan

315

NREL: Distributed Grid Integration - Solar Distributed Grid Integration  

NLE Websites -- All DOE Office Websites (Extended Search)

Solar Distributed Grid Integration Projects Solar Distributed Grid Integration Projects NREL provides grid integration support, system-level testing, and systems analysis for DOE's Solar Distributed Grid Integration Projects supported by the SunShot Initiative. These projects address technical issues and develop solutions for high penetration grid integration of solar technologies into the electric power system to meet the following goals: Reduce cost: reduce interconnection costs by developing streamlined procedures including advanced integration models for utility interconnection of photovoltaics (PV) Reduce market barriers: work with utilities and system integrators to reduce market barriers by providing research on impacts of integration of high penetration of PV systems and developing solutions.

316

Energy Systems Integration  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Systems Integration Systems Integration Ben Kroposki, PhD, PE Director, Energy Systems Integration National Renewable Energy Laboratory 2 Reducing investment risk and optimizing systems in a rapidly changing energy world * Increasing penetration of variable RE in grid * Increasing ultra high energy efficiency buildings and controllable loads * New data, information, communications and controls * Electrification of transportation and alternative fuels * Integrating energy storage (stationary and mobile) and thermal storage * Interactions between electricity/thermal/fuels/data pathways * Increasing system flexibility and intelligence Current Energy Systems Future Energy Systems Why Energy Systems Integration? 3 Energy Systems Integration Continuum Scale Appliance (Plug)

317

Integrated polymer solar cells in serial architecture with patterned charge-transporting MoOx for miniature high-voltage sources  

Science Journals Connector (OSTI)

We develop miniature high-voltage sources from polymer solar cells (PSCs) with charge-transporting molybdenum oxide (MoOx) integrated in a serial architecture through sacrificial layer (SL)-assisted patterning. The MoOx layer, being patterned by the lift-off process of the SL of a hydrophobic fluorinated-polymer, as a hole transporting layer plays a critical role on the reduction of the dark current and the increase of a high open circuit voltage of an integrated PSC array. The underlying mechanism lies primarily on the elimination of the lateral charge pathways in the MoOx layer in the presence of the electrode interconnection. Two miniature voltage sources consisting of 20 PSCs and 50 PSCs are demonstrated in the operation of a liquid crystal display and an organic field-effect transistor, respectively. Our SL-assisted integration approach will be directly applicable for implementing the self-power sources made of the PSCs into a wide range of the electronic and optoelectronic devices.

Seong-Min Cho; Chang-Min Keum; Hea-Lim Park; Min-Hoi Kim; Jin-Hyuk Bae; Sin-Doo Lee

2014-01-01T23:59:59.000Z

318

Active Scheme to Measure Throughput of Wireless Access Link in Hybrid Wired-Wireless Network  

E-Print Network (OSTI)

, at the wireless The authors are with Networking Research Laboratory, Department of Electrical and Computer1 Active Scheme to Measure Throughput of Wireless Access Link in Hybrid Wired-Wireless Network to measure the download throughput of an IEEE 802.11 wireless access link in a hybrid wired-wireless network

Rojas-Cessa, Roberto

319

Monolithic Integrations of Slanted Silicon Nanostructures on 3D Microstructures and Their Application to Surface Enhanced Raman Spectroscopy  

E-Print Network (OSTI)

We demonstrated fabrication of black silicon with slanted nanocone array on both planar and 3D micro and meso scale structures produced by a high-throughput lithography-free oblique-angle plasma etching process. Nanocones with gradual change in height were created on the same piece of silicon. The relation between the slanted angle of nanocones and incident angle of directional plasma is experimentally investigated. In order to demonstrate the monolithic integration of nanostructures on micro and meso scale non-planar surfaces, nanocone forest is fabricated on non-planar silicon surfaces in various morphologies such as silicon atomic force microscopy (AFM) tips and pyramidal pits. By integrating nanocones on inverse silicon micro-pyramid array devices, we further improved the surface enhanced Raman scattering (SERS) enhancement property of this optimized commercial SERS substrate by several folds even when using 66% less noble metal coating. We investigated the length gradient dependence and asymmetric proper...

Xu, Zhida

2014-01-01T23:59:59.000Z

320

Netest: A Tool to Measure the Maximum Burst Size, Available Bandwidth and Achievable Throughput  

SciTech Connect

Distinguishing available bandwidth and achievable throughput is essential for improving network applications' performance. Achievable throughput is the throughput considering a number of factors such as network protocol, host speed, network path, and TCP buffer space, where as available bandwidth only considers the network path. Without understanding this difference, trying to improve network applications' performance is like ''blind men feeling the elephant'' [4]. In this paper, we define and distinguish bandwidth and throughput, and debate which part of each is achievable and which is available. Also, we introduce and discuss a new concept - Maximum Burst Size that is crucial to the network performance and bandwidth sharing. A tool, netest, is introduced to help users to determine the available bandwidth, and provides information to achieve better throughput with fairness of sharing the available bandwidth, thus reducing misuse of the network.

Jin, Guojun; Tierney, Brian

2003-01-31T23:59:59.000Z

Note: This page contains sample records for the topic "integrated high throughput" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


321

Potential Impact of Interfacial Bonding Efficiency on High-Burnup Spent Nuclear Fuel Vibration Integrity during Normal Transportation  

SciTech Connect

Finite element analysis (FEA) was used to investigate the impacts of interfacial bonding efficiency at pellet pellet and pellet clad interfaces on spent nuclear fuel (SNF) vibration integrity. The FEA simulation results were also validated and benchmarked with reverse bending fatigue test results on surrogate rods consisting of stainless steel (SS) tubes with alumina-pellet inserts. Bending moments (M) are applied to the FEA models to evaluate the system responses of the surrogate rods. From the induced curvature, , the flexural rigidity EI can be estimated as EI=M/ . The impacts of interfacial bonding efficiency on SNF vibration integrity include the moment carrying capacity distribution between pellets and clad and the impact of cohesion on the flexural rigidity of the surrogate rod system. The result also indicates that the immediate consequences of interfacial de-bonding are a load carrying capacity shift from the fuel pellets to the clad and a reduction of the composite rod flexural rigidity. Therefore, the flexural rigidity of the surrogate rod and the bending moment bearing capacity between the clad and fuel pellets are strongly dependent on the efficiency of interfacial bonding at the pellet pellet and pellet clad interfaces. The above-noted phenomenon was calibrated and validated by reverse bending fatigue testing using a surrogate rod system.

Jiang, Hao [ORNL] [ORNL; Wang, Jy-An John [ORNL] [ORNL; Wang, Hong [ORNL] [ORNL

2014-01-01T23:59:59.000Z

322

Proposed design requirements for high-integrity containers used to store, transport, and dispose of high-specific-activity, low-level radioactive wastes from Three Mile Island Unit II  

SciTech Connect

This report develops proposed design requirements for high integrity containers used to store, transport and/or dispose of high-activity, low-level radioactive wastes from Three Mile Island Unit II. The wastes considered are the dewatered resins produced by the EPICOR II waste treatment system used to clean-up the auxiliary building water. The radioactivity level of some of these EPICOR II liners is 1300 curies per container. These wastes may be disposed of in an intermediate depth burial (10 to 20 meter depth) facility. The proposed container design requirements are directed to ensure isolation of the waste and protection of the public health and safety.

Vigil, M.G.; Allen, G.C.; Pope, R.B.

1981-04-01T23:59:59.000Z

323

Si-CMOS-Like Integration of AlGaN/GaN Dielectric-Gated High-Electron-Mobility Transistors  

E-Print Network (OSTI)

the engineering of high mobility, high carrier density channels at III-Nitride heterointerfaces. In order to seize market share from silicon, the cost of manufacturing GaN-based devices must be further reduced. With the successful realization of 200mm GaN-on-Si...

Johnson, Derek Wade

2014-07-31T23:59:59.000Z

324

High throughput parallel backside contacting and periodic texturing for high-efficiency solar cells  

SciTech Connect

Disclosed are configurations of long-range ordered features of solar cell materials, and methods for forming same. Some features include electrical access openings through a backing layer to a photovoltaic material in the solar cell. Some features include textured features disposed adjacent a surface of a solar cell material. Typically the long-range ordered features are formed by ablating the solar cell material with a laser interference pattern from at least two laser beams.

Daniel, Claus; Blue, Craig A.; Ott, Ronald D.

2014-08-19T23:59:59.000Z

325

Bayesian Model Selection for High-dimensional High-throughput Data  

E-Print Network (OSTI)

(d + 2i) [ ??C?11? n? ]k ??C?11 ? ? 1 2 (2pin?) d 2 exp [ ? ??C?11? 2n? ] , (2.16) which leads to a Bayes? factor for testing hypothesis in equation (2.12) versus (2.13) that can be expressed as 15 BFM(2|1) = ??k k?1? i=0 (d... (d + 2i) [ ??C?11? n? ]k ??C?11 ? ? 1 2 (2pin?) d 2 exp [ ? ??C?11? 2n? ] , (2.16) which leads to a Bayes? factor for testing hypothesis in equation (2.12) versus (2.13) that can be expressed as 15 BFM(2|1) = ??k k?1? i=0 (d...

Joshi, Adarsh

2012-07-16T23:59:59.000Z

326

High-Throughput Methodology for Discovery of Metal-Organic Frameworks with a High  

E-Print Network (OSTI)

of California, Berkeley Lily Ackerman and Thomas R. Boussie Symyx Technologies, Inc. #12;A Tetrazolate

327

Ultra-high-aspect-ratio nanofluidic channels for high-throughput biological applications  

E-Print Network (OSTI)

The development of micro/nanofluidics is expected to be the enabling technology for sample preparation of proteomic biosamples, which has been the bottleneck in proteomics. Most microfabricated nanofluidic channels, such ...

Mao, Pan

2009-01-01T23:59:59.000Z

328

ExperiBase : an integrated software architecture to support modern experimental biology  

E-Print Network (OSTI)

Over the past several years, the explosive growth of biological data generated by new high-throughput instruments has virtually begun to drown the biological community. There is no established infrastructure to deal with ...

Zhang, Shixin, 1970-

2004-01-01T23:59:59.000Z

329

Development of an Integrated Raman and Turbidity Fiber Optic Sensor for the In-Situ Analysis of High Level Nuclear Waste - 13532  

SciTech Connect

Stored nuclear waste must be retrieved from storage, treated, separated into low- and high-level waste streams, and finally put into a disposal form that effectively encapsulates the waste and isolates it from the environment for a long period of time. Before waste retrieval can be done, waste composition needs to be characterized so that proper safety precautions can be implemented during the retrieval process. In addition, there is a need for active monitoring of the dynamic chemistry of the waste during storage since the waste composition can become highly corrosive. This work describes the development of a novel, integrated fiber optic Raman and light scattering probe for in situ use in nuclear waste solutions. The dual Raman and turbidity sensor provides simultaneous chemical identification of nuclear waste as well as information concerning the suspended particles in the waste using a common laser excitation source. (authors)

Gasbarro, Christina; Bello, Job [EIC Laboratories, Inc., 111 Downey St., Norwood, MA, 02062 (United States)] [EIC Laboratories, Inc., 111 Downey St., Norwood, MA, 02062 (United States); Bryan, Samuel; Lines, Amanda; Levitskaia, Tatiana [Pacific Northwest National Laboratory, PO Box 999, Richland, WA, 99352 (United States)] [Pacific Northwest National Laboratory, PO Box 999, Richland, WA, 99352 (United States)

2013-07-01T23:59:59.000Z

330

HLW System Integrated Project Team  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

l l W S Hi h l W S High Level Waste System High Level Waste System Integrated Project Team Integrated Project Team Integrated Project Team Integrated Project Team Steve Schneider Steve Schneider Office of Engineering and Technology High Level Waste Corporate Board March 5, 2009 This document is intended for planning and analysis purposes, assuming a continuing constrained budget environment. Every effort will be made to comply with all applicable environmental and legal obligations, while also assuring that essential functions necessary to protect human health, the environment and national security are maintained. 1 Introduction Introduction Introduction Introduction Challenges and Priorities High Level Waste Strategic Initiative Results High Level Waste System Integrated

331

High Performance Interconnect System Design for Future Chip Multiprocessors  

E-Print Network (OSTI)

constraints of power and area, and provide ultra low latencies and high throughput. In this research, we explore different techniques to design high performance NOC. First, existing NOCs mostly use Dimension Order Routing (DOR) to determine the route taken...

Wang, Lei

2013-05-02T23:59:59.000Z

332

High-Performance Integrated Dual-Gate AlGaN/GaN Enhancement-Mode Transistor  

E-Print Network (OSTI)

In this letter, we present a new AlGaN/GaN enhancement-mode (E-mode) transistor based on a dual-gate structure. The dual gate allows the transistor to combine an E-mode behavior with low on-resistance and very high breakdown ...

Lu, Bin

333

A radiation-hardened, low-noise, high-speed, integrated charge preamplifier for the Superconducting Supercollider  

E-Print Network (OSTI)

F, in order to provide the sensitivity needed; refer to equation (1. 1). The reason for lowering the detector capacitance and increasing the number of chaiui lr is to iinprcve the energy resolutiou and uniformity of response over the volume ot... calorimeters leave the front ? end readout electron- ics outside. Annual gamma doses of 100 kRad or as high as 1 MRad and neutron doses in the order of 2x10 /cm are expected, depending upon the locations of the detectors. Hence, charge preamplifiers have...

Ling, Kuok Young

2012-06-07T23:59:59.000Z

334

Throughput-Efficient Network-on-Chip Router Design with STT-MRAM  

E-Print Network (OSTI)

-efficient buffer refreshing schemes synergized with age-based switch arbitration that gives higher priority to older flits to remove unnecessary refreshing operations. On an average, we observed throughput improvements of 16% on synthetic workloads and benchmarks....

Narayana, Sagar 1986-

2012-11-02T23:59:59.000Z

335

Integrated Operation of INL HYTEST System and High-Temperature Steam Electrolysis for Synthetic Natural Gas Production  

SciTech Connect

The primary feedstock for synthetic fuel production is syngas, a mixture of carbon monoxide and hydrogen. Current hydrogen production technologies rely upon fossil fuels and produce significant quantities of greenhouse gases as a byproduct. This is not a sustainable means of satisfying future hydrogen demands, given the current projections for conventional world oil production and future targets for carbon emissions. For the past six years, the Idaho National Laboratory has been investigating the use of high-temperature steam electrolysis (HTSE) to produce the hydrogen feedstock required for synthetic fuel production. High-temperature electrolysis water-splitting technology, combined with non-carbon-emitting energy sources, can provide a sustainable, environmentally-friendly means of large-scale hydrogen production. Additionally, laboratory facilities are being developed at the INL for testing hybrid energy systems composed of several tightly-coupled chemical processes (HYTEST program). The first such test involved the coupling of HTSE, CO2 separation membrane, reverse shift reaction, and methanation reaction to demonstrate synthetic natural gas production from a feedstock of water and either CO or a simulated flue gas containing CO2. This paper will introduce the initial HTSE and HYTEST testing facilities, overall coupling of the technologies, testing results, and future plans.

Carl Marcel Stoots; Lee Shunn; James O'Brien

2010-06-01T23:59:59.000Z

336

RECIPIENT:Princeton Power Systems STATE: NJ PROJECT Marine High-Voltage Power Conditioning and Transmission System with Integrated Energy Storage  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Princeton Power Systems Princeton Power Systems STATE: NJ PROJECT Marine High-Voltage Power Conditioning and Transmission System with Integrated Energy Storage TITLE: Funding Opportunity Announcement Number Procurement Instrument Number NEPA Control Number cm Number DE-FOA-0000293 DE-EE0003640 GFO-000364~001 GOO Based on my review of the information concerning the proposed action, as NEPA Compliance Officer (authorized under DOE Order 451.1A), I have made the foUowing determination: CX, EA, EIS APPENDIX AND NUMBER: Description: A9 Information gathering (including, but not limited to, ~terature surveys, inventories, audits), data analysis (including computer modeling), document preparation (such as conceptual design or feasibility studies, analytical energy supply

337

High-throughput sample handling and data collection at synchrotrons: embedding the ESRF into the high-throughput gene-to-structure pipeline  

Science Journals Connector (OSTI)

Automated data collection for macromolecular crystallography at beamlines with protocols for automatic instrumentation improves the efficient use of available beamtime. These developments were a result of a collaboration between the main partners of SPINE and members of other similar European and national initiatives.

Beteva, A.

2006-09-19T23:59:59.000Z

338

Status of the development of a fully integrated code system for the simulation of high temperature reactor cores  

Science Journals Connector (OSTI)

Abstract The HTR code package (HCP) is a new code system, which couples a variety of stand-alone codes for the simulation of different aspects of HTR. HCP will allow the steady-state and transient operating conditions of a 3D reactor core to be simulated including new features such as spatially resolved fission product release calculations or production and transport of graphite dust. For this code the latest programming techniques and standards are applied. As a first step an object-oriented data model was developed which features a high level of readability because it is based on problem-specific data types like Nuclide, Reaction, ReactionHandler, CrossSectionSet, etc. Those classes help to encapsulate and therefore hide specific implementations, which are not relevant with respect to physics. HCP will make use of one consistent data library for which an automatic generation tool was developed. The new data library consists of decay information, cross sections, fission yields, scattering matrices etc. for all available nuclides (e.g. ENDF/B-VII.1). The data can be stored in different formats such as binary, ASCII or XML. The new burn up code TNT (Topological Nuclide Transmutation) applies graph theory to represent nuclide chains and to minimize the calculation effort when solving the burn up equations. New features are the use of energy-dependent fission yields or the calculation of thermal power for decay, fission and capture reactions. With STACY (source term analysis code system) the fission product release for steady state as well as accident scenarios can be simulated for each fuel batch. For a full-core release calculation several thousand fuel elements are tracked while passing through the core. This models the stochastic behavior of a pebble bed in a realistic manner. In this paper we report on the current status of the HCP and present first results, which prove the applicability of the selected approach.

Stefan Kasselmann; Claudia Druska; Stefan Herber; Stephan Jhe; Florian Keller; Daniela Lambertz; Jingjing Li; Sarah Scholthaus; Dunfu Shi; Andre Xhonneux; Hans-Josef Allelein

2014-01-01T23:59:59.000Z

339

Appeared in the Sixth International Symposium on High-Performance Computer Architecture (HPCA), January 2000. Impact of Chip-Level Integration on  

E-Print Network (OSTI)

), January 2000. Impact of Chip-Level Integration on Performance of OLTP Workloads Luiz Andr´e Barroso

Barroso, Luiz André

340

Integral Field Spectroscopy based H\\alpha\\ sizes of local Luminous and Ultraluminous Infrared Galaxies. A Direct Comparison with high-z Massive Star Forming Galaxies  

E-Print Network (OSTI)

Aims. We study the analogy between local U/LIRGs and high-z massive SFGs by comparing basic H{\\alpha} structural characteristics, like size, luminosity and Star Formation Rate (SFR) surface density, in an homogeneous way (i.e. same tracer and size definition, similar physical scales). Methods. We use Integral Field Spectroscopy based H{\\alpha} emission maps for a representative sample of 54 local U/LIRGs (66 galaxies). From this initial sample we select 26 objects with H{\\alpha} luminosities (L(H{\\alpha})) similar to those of massive (i.e. M\\ast \\sim 10^10 M\\odot or larger) SFGs at z \\sim 2, and probing similar physical scales. Results. The sizes of the H{\\alpha} emitting region in the sample of local U/LIRGs span a large range, with r1/2(H{\\alpha}) from 0.2 to 7 kpc. However, about 2/3 of local U/LIRGs with Lir > 10^11.4 L\\odot have compact H{\\alpha} emission (i.e. r1/2 2 kpc). These are systems showing pre-coalescence merger activity and they are indistinguishable from the massive high-z SFGs galaxies in t...

Arribas, S; Alonso-Herrero, A; Rosales-Ortega, F F; Monreal-Ibero, A; Garca-Marn, M; Garca-Burillo, S; Rodrguez-Zaurn, J

2012-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "integrated high throughput" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


341

Analysis and Simulation of Fuel Consumption and Energy Throughput on a Parallel Diesel-Electric Hybrid Powertrain.  

E-Print Network (OSTI)

??The aim of this master thesis is to study the energy throughput and fuel consumption of a parallel diesel-electric hybrid vehicle. This has been done (more)

Gustafsson, Johanna

2009-01-01T23:59:59.000Z

342

Challenges in Integrating Renewable Technologies  

E-Print Network (OSTI)

. To seamlessly integrate renewable resources in the grid, research and development must address challenges reliability and econ- omy. The challenges of integrating high penetrations of renewable energy technologiesChallenges in Integrating Renewable Technologies into an Electric Power System White Paper Power

343

A Service Oriented Architecture for Exploring High Performance Distributed Power Models  

SciTech Connect

Power grids are increasingly incorporating high quality, high throughput sensor devices inside power distribution networks. These devices are driving an unprecedented increase in the volume and rate of available information. The real-time requirements for handling this data are beyond the capacity of conventional power models running in central utilities. Hence, we are exploring distributed power models deployed at the regional scale. The connection of these models for a larger geographic region is supported by a distributed system architecture. This architecture is built in a service oriented style, whereby distributed power models running on high performance clusters are exposed as services. Each service is semantically annotated and therefore can be discovered through a service catalog and composed into workflows. The overall architecture has been implemented as an integrated workflow environment useful for power researchers to explore newly developed distributed power models.

Liu, Yan; Chase, Jared M.; Gorton, Ian

2012-11-12T23:59:59.000Z

344

Reduction of a grid moire pattern by integrating a carbon-interspaced high precision x-ray grid with a digital radiographic detector  

SciTech Connect

The stationary grid commonly used with a digital x-ray detector causes a moire interference pattern due to the inadequate sampling of the grid shadows by the detector pixels. There are limitations with the previous methods used to remove the moire such as imperfect electromagnetic interference shielding and the loss of image information. A new method is proposed for removing the moire pattern by integrating a carbon-interspaced high precision x-ray grid with high grid line uniformity with the detector for frequency matching. The grid was aligned to the detector by translating and rotating the x-ray grid with respect to the detector using microcontrolled alignment mechanism. The gap between the grid and the detector surface was adjusted with micrometer precision to precisely match the projected grid line pitch to the detector pixel pitch. Considering the magnification of the grid shadows on the detector plane, the grids were manufactured such that the grid line frequency was slightly higher than the detector sampling frequency. This study examined the factors that affect the moire pattern, particularly the line frequency and displacement. The frequency of the moire pattern was found to be sensitive to the angular displacement of the grid with respect to the detector while the horizontal translation alters the phase but not the moire frequency. The frequency of the moire pattern also decreased with decreasing difference in frequency between the grid and the detector, and a moire-free image was produced after complete matching for a given source to detector distance. The image quality factors including the contrast, signal-to-noise ratio and uniformity in the images with and without the moire pattern were investigated.

Yoon, Jai-Woong; Park, Young-Guk; Park, Chun-Joo; Kim, Do-Il; Lee, Jin-Ho; Chung, Nag-Kun; Choe, Bo-Young; Suh, Tae-Suk; Lee, Hyoung-Koo [Department of Biomedical Engineering, College of Medicine, The Catholic University of Korea, Seoul 137-701 (Korea, Republic of); Jungwon Precision Ind. Co., Ltd, 425-833, Ansan (Korea, Republic of); Department of Biomedical Engineering, College of Medicine, The Catholic University of Korea, Seoul 137-701 (Korea, Republic of); Jungwon Precision Ind. Co., Ltd, 425-833, Ansan (Korea, Republic of); Department of Biomedical Engineering, College of Medicine, The Catholic University of Korea, Seoul 137-701 (Korea, Republic of)

2007-11-15T23:59:59.000Z

345

High-Performance Single Cell Genetic Analysis Using Microfluidic Emulsion Generator Arrays  

E-Print Network (OSTI)

High-Performance Single Cell Genetic Analysis Using Microfluidic Emulsion Generator Arrays Yong high-throughput microfluidic emulsion generation with single cell multiplex polymerase chain reaction and to provide good statistical information regarding these stochastic events. Microfluidics offers unprecedented

California at Berkeley, University of

346

A Deeply Pipelined CABAC Decoder for HEVC Supporting Level 6.2 High-tier Applications  

E-Print Network (OSTI)

High Efficiency Video Coding (HEVC) is the latest video coding standard that specifies video resolutions up to 8K Ultra-HD (UHD) at 120 fps to support the next decade of video applications. This results in high-throughput ...

Chen, Yu-Hsin

347

IEEE TRANSACTIONS ON INDUSTRY APPLICATIONS, VOL. 41, NO. 2, MARCH/APRIL 2005 507 Integrated High-Speed Intelligent Utility Tie Unit for  

E-Print Network (OSTI)

is to rejuvenate the idea of integrated resource planning and promote the distributed generation via traditional paradigm of the vertically integrated electrical utility structure has begun to change. In the United States, the Federal Energy Regula- tory Commission has issued several rules and Notices of Proposed

Oraintara, Soontorn

348

Insolation integrator  

DOE Patents (OSTI)

An electric signal representative of the rate of insolation is integrated to determine if it is adequate for operation of a solar energy collection system.

Dougherty, John J. (Norristown, PA); Rudge, George T. (Lansdale, PA)

1980-01-01T23:59:59.000Z

349

SunShot Initiative: Systems Integration  

NLE Websites -- All DOE Office Websites (Extended Search)

Systems Integration to someone by Systems Integration to someone by E-mail Share SunShot Initiative: Systems Integration on Facebook Tweet about SunShot Initiative: Systems Integration on Twitter Bookmark SunShot Initiative: Systems Integration on Google Bookmark SunShot Initiative: Systems Integration on Delicious Rank SunShot Initiative: Systems Integration on Digg Find More places to share SunShot Initiative: Systems Integration on AddThis.com... Concentrating Solar Power Photovoltaics Systems Integration Research, Development, & Demonstration Competitive Awards Balance of Systems Systems Integration High Penetration Solar Portal The High Penetration Solar Portal has timely information related to high penetration solar scenarios and integrating solar into the grid. The site allows utilities, grant awardees, regulators, researchers, and other solar

350

Eastern Renewable Generation Integration Study (Presentation)  

SciTech Connect

This presentation provides a high-level overview of the Eastern Renewable Generation Integration Study process, scenarios, tools, and goals.

Bloom, A.

2014-05-01T23:59:59.000Z

351

Throughput-driven design of networks-on-chip  

E-Print Network (OSTI)

Symposium on Computer Architecture, ISCA 06, pages 130 [18]on High Performance Computer Architecture, HPCA 08, pagessymposium on Computer architecture, ISCA 07, pages 138149,

Sunkam Ramanujam, Rohit

2011-01-01T23:59:59.000Z

352

Joint Power Control and Link Scheduling in Wireless Networks for Throughput Optimization  

E-Print Network (OSTI)

Joint Power Control and Link Scheduling in Wireless Networks for Throughput Optimization Liqun Fu formulate the general joint link scheduling and power control problem as an in- teger linear programming optimality. Index Terms--scheduling, power control, SINR constraints. I. INTRODUCTION Due to their unconfined

Huang, Jianwei

353

Fixed Point Analysis of the Saturation Throughput of IEEE 802.11 WLANs with Capture  

E-Print Network (OSTI)

1 Fixed Point Analysis of the Saturation Throughput of IEEE 802.11 WLANs with Capture Venkatesh capture, fading or frame error), using a fixed point framework developed in [7]. Here, we extend the work then obtain the fixed point equations for the infrastructure model. We show that these equations accurately

Kumar, Anurag

354

Cherish every Joule: Maximizing throughput with an eye on network-wide energy consumption  

E-Print Network (OSTI)

Cherish every Joule: Maximizing throughput with an eye on network-wide energy consumption Canming: {jcm, yshi, thou, wjlou}@vt.edu Abstract Conserving network-wide energy consumption is becoming of wireless networks, the concern of energy consumption is becoming in- creasingly important for network

Hou, Y. Thomas

355

ANALYSIS OF ALTERNATIVE COLLABORATIVE ROUTE SELECTION STRATEGIES BASED ON COST AND THROUGHPUT  

E-Print Network (OSTI)

) and the airspace users (AOCs). The result of the collaboration should be an outcome that maximizes the utility analysis between flight costs and sector throughput for combinations of ATCSCC and AOC strategies) restrictions for the airspace, as well as, TFM re- routing in collaboration with the AOC takes place

356

Throughput and Ergodic Capacity of Wireless Energy Harvesting Based DF Relaying Network  

E-Print Network (OSTI)

-to-point communication systems and studied rate-energy trade-off assuming single-input-single-output (SISO) [1], [3Throughput and Ergodic Capacity of Wireless Energy Harvesting Based DF Relaying Network Ali A-and-forward (DF) relaying network based on wireless energy harvesting. The energy constrained relay node first

Zhou, Xiangyun "Sean"

357

MIMO Ad Hoc Networks: Medium Access Control, Saturation Throughput and Optimal Hop Distance  

E-Print Network (OSTI)

1 MIMO Ad Hoc Networks: Medium Access Control, Saturation Throughput and Optimal Hop Distance Ming in mobile ad hoc networks. Specifically, we focus on ad hoc networks where the spa- tial diversity technique technique can enhance the performance of mobile ad hoc networks significantly. Key words: ad hoc networks

Reisslein, Martin

358

Area and Throughput Trade-Offs in the Design of Pipelined Discrete Wavelet Transform Architectures  

E-Print Network (OSTI)

Area and Throughput Trade-Offs in the Design of Pipelined Discrete Wavelet Transform Architectures wavelet transform (DWT) as a linear space-to-frequency transform of the image domain in an irreversible compression. This irreversible discrete wavelet transform is implemented by FIR filter using 9/7 Daubechies

Boyer, Edmond

359

Short-Term Throughput Maximization for Battery Limited Energy Harvesting Nodes  

E-Print Network (OSTI)

for energy recharge. Under the assumption of an increasing concave power-rate relationship, the short completion time of a given amount of data were found for an energy harvesting node under the assumptionShort-Term Throughput Maximization for Battery Limited Energy Harvesting Nodes Kaya Tutuncuoglu

Yener, Aylin

360

The Effects of Task Dimensionality, Endpoint Deviation, Throughput Calculation, and Experiment Design on  

E-Print Network (OSTI)

The Effects of Task Dimensionality, Endpoint Deviation, Throughput Calculation, and Experiment Design on Pointing Measures and Models Jacob O. Wobbrock, Kristen Shinohara and Alex Jansen and Fitts' law models in general are invariant to task dimensionality (1-D vs. 2-D), whether univariate (SDx

Anderson, Richard

Note: This page contains sample records for the topic "integrated high throughput" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


361

A Framework for Throughput and Energy Efficiency in Mobile ad Hoc Networks  

E-Print Network (OSTI)

throughput and energy consumption - while maintaining connectivity. As an application, we evaluate two well on exhaustible power sources, such as batteries, and hence have strict requirements on the energy consumption networks which allows us to compare the average energy and time cost of different networks but exhibiting

Paris-Sud XI, Université de

362

Minimizing the Energy Cost of Throughput in a Linear Pipeline by Opportunistic Time Borrowing  

E-Print Network (OSTI)

Minimizing the Energy Cost of Throughput in a Linear Pipeline by Opportunistic Time Borrowing a technique to optimize the energy-delay product of a synchronous linear pipeline circuit with dynamic error and clock frequency of the design by exploiting slacks that are present in various stages of the pipeline

Pedram, Massoud

363

Maximizing Throughput of UAV-Relaying Networks with the Load-Carry-and-Deliver Paradigm  

E-Print Network (OSTI)

act as relays between ground stations that could not otherwise communicate due to distanceMaximizing Throughput of UAV-Relaying Networks with the Load-Carry-and-Deliver Paradigm Chen Unmanned Aerial Vehicles (UAVs) to relay messages between two distant ground nodes. For delay

Kung, H. T.

364

High Performance Mixed Signal Circuits Enabled by the Direct Monolithic Heterogeneous Integration of InP HBT and Si CMOS on a Silicon Substrate  

E-Print Network (OSTI)

We present recent results on the direct heterogeneous integration of InP HBTs and Si CMOS on a silicon template wafer or SOLES (Silicon On Lattice Engineered Substrate). InP HBTs whose performance are comparable to HBTs ...

Kazior, T. E.

365

high  

Gasoline and Diesel Fuel Update (EIA)

0 0 Summary Our short-term outlook for a wide array of energy prices has been adjusted upward as international and domestic energy supply conditions have tightened. We think that crude oil prices are as likely as not to end the year $2 to $3 per barrel higher than our previous projections. Thus, we think that the probability of West Texas Intermediate costing an average of $30 per barrel or more at midwinter is about 50 percent. On their current track, heating oil prices are likely to be about 30 percent above year-ago levels in the fourth quarter. Prices for Q1 2001 seem more likely now to match or exceed the high level seen in Q1 2000. Tight oil markets this year and an inherent propensity for high gas utilization in incremental power supply have resulted in rising North American natural gas

366

Cobalt Precursors for High-Throughput Discovery of Base Metal Asymmetric Alkene Hydrogenation Catalysts  

Science Journals Connector (OSTI)

...earth-abundant elements such as iron and cobalt are attractive because...precursor, Co(acac) 3 (acac, acetylacetonate). A selection of commercially available...12515512 22 B. Plietker, Ed., Iron Catalysis in Organic Chemistry...

Max R. Friedfeld; Michael Shevlin; Jordan M. Hoyt; Shane W. Krska; Matthew T. Tudge; Paul J. Chirik

2013-11-29T23:59:59.000Z

367

PVD synthesis and high-throughput property characterization of Ni?Fe?Cr alloy libraries  

SciTech Connect

Three methods of alloy library synthesis, thick-layer deposition followed by interdiffusion, composition-spread codeposition and electron-beam melting of thick deposited layers, have been applied to Ni-Fe-Cr ternary and Ni-Cr binary alloys. Structural XRD mapping and mechanical characterization by means of nanoindentation have been used to characterize the properties of the libraries. The library synthesis methods are compared from the point of view of the structural and mechanical information they can provide.

Rar, A.; Frafjord, J.J.; Fowlkes, Jason D.; Specht, E.D.; Rack, P.D.; Santella, M.L.; Bei, H.; George, E.P.; Pharr, G.M. (Tennessee-K); (Tennessee-K); (ORNL)

2010-11-10T23:59:59.000Z

368

High-Throughput Computational Screening of thermal conductivity, Debye temperature and Gruneisen parameter  

E-Print Network (OSTI)

thermal properties such as the Debye temperature and the thermal conductivity of materials. We demonstrate studied for the past few decades6 . Low thermal conductivity mate- rials constitute the basis of a new and predict the thermal conductivity of differ- ent materials8,9,11­16 . Such evaluation of the higher

Curtarolo, Stefano

369

High-Throughput 3D Homology Detection via NMR Resonance Assignment  

E-Print Network (OSTI)

-ray crystallography or Nuclear Magnetic Resonance (NMR), is very costly and time-consuming. Consequently protein and c is the maximum edge weight in an integer- weighted bipartite graph. Our experiments on real experimental data. Abbreviations used: NMR, nuclear magnetic resonance; RDC, residual dipolar coupling; 3D

Langmead, Christopher James

370

High-Throughput 3D Structural Homology Detection via NMR Resonance Christopher James Langmead  

E-Print Network (OSTI)

's structure experimentally, via X-ray crystallography or Nuclear Magnetic Resonance (NMR), is very costly bipartite graph. Our experiments on real NMR data from 3 different proteins against a database of 4-646-3173. Fax: 603-646-1672. Email: brd@cs.dartmouth.edu Abbreviations used: NMR, nuclear magnetic resonance

Richardson, David

371

A microfluidics approach towards high-throughput pathogen removal from blood using margination  

E-Print Network (OSTI)

Sepsis is an adverse systemic inflammatory response caused by microbial infection in blood. This paper reports a simple microfluidic approach for intrinsic, non-specific removal of both microbes and inflammatory cellular ...

Hou, Han Wei

372

High-throughput synthesis and characterization of vanadium mixed metal oxide pigments using synchroton radiation.  

E-Print Network (OSTI)

??UNA range of inorganic vanadium mixed metal oxides, with potential applications as inorganic pigments, have been synthesised and characterised in terms of their crystal structure, (more)

Russu, Sergio

2008-01-01T23:59:59.000Z

373

SUPPLEMENTAL INFORMATION Treatability of Complex Effluents in High-Throughput and Bench Scale Microbial  

E-Print Network (OSTI)

. The efficiency was calculated using only recovered hydrogen and combined hydrogen and methane, using the heat of combustion to calculate the energy contained in the gas. Figure S13. Open circuit gas production and COD

374

Analysis of High-Throughput Sequencing and Annotation Strategies for Phage Genomes  

E-Print Network (OSTI)

Background: Bacterial viruses (phages) play a critical role in shaping microbial populations as they influence both host mortality and horizontal gene transfer. As such, they have a significant impact on local and global ...

Chisholm, Sallie (Penny)

375

Potential of High-Throughput Experimentation with Ammonia Borane Solid Hydrogen Storage Materials (presentation)  

Energy.gov (U.S. Department of Energy (DOE))

Presented at the U.S. Department of Energy's Hydrogen Storage Meeting held June 26, 2007 in Bethesda, Maryland.

376

Exploiting Domain Knowledge for Improved Quantitative High-Throughput Screening Curve Fitting  

Science Journals Connector (OSTI)

One popular measure of curve-fitting (or regression) performance obtained from the REC curve is its area over the curve (AOC):The AOC is the area between a curve and the horizontal line at unit accuracy; a smaller AOC is desirable. ... The AOC is a reasonable estimate of the mean absolute error (MAE). ... This scatter plot compares the AOC (eq 10) for the LS- and DK-fitter techniques for all 43 qHTS screens considered in this study. ...

Charles Bergeron; Gregory Moore; Michael Krein; Curt M. Breneman; Kristin P. Bennett

2011-10-14T23:59:59.000Z

377

High-Throughput Methods To Assess Lipophilic and Hydrophilic Antioxidant Capacity of Food Extracts in Vitro  

Science Journals Connector (OSTI)

Assays comprising three probes for different mechanisms of antioxidant activity in food products have been modified to allow better comparison of the contributions of the different mechanisms to antioxidant capacity (AOC). ... The mixture was incubated at 50 C for 15 min, and the absorbance was measured at 760 nm (UV?vis spectrophotometer Lambda 12, Perkin-Elmer AG). ...

D. Jimenez-Alvarez; F. Giuffrida; F. Vanrobaeys; P. A. Golay; C. Cotting; A. Lardeau; Brendan J. Keely

2008-04-24T23:59:59.000Z

378

High Throughput Web Inspection System using Time-stretch Real-time Imaging  

E-Print Network (OSTI)

successfully report a dark-field web inspection system withsample substrate for our dark-field web inspection systemweb inspection system exploiting time- stretch and utilizing the merits coming from dark-

Kim, Chanju

2013-01-01T23:59:59.000Z

379

High-Throughput Program for the Discovery of NOx Reduction Catalysts...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

2004deerblint.pdf More Documents & Publications WA02042GENERALMOTORSPOWERTRAINDIVWaiverofDomestic.pdf Heavy-Duty NOx Emissions Control: Reformer-Assisted vs....

380

E-Print Network 3.0 - automated high throughput Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

Engineering, Cornell University Collection: Chemistry ; Engineering 35 THE RABIT: A RAPID AUTOMATED BIODOSIMETRY TOOL FOR RADIOLOGICAL TRIAGE Summary: goals, and describe...

Note: This page contains sample records for the topic "integrated high throughput" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


381

High-Throughput In Situ Parametric Studies of Cytochrome P450 Catalysis  

E-Print Network (OSTI)

of data quality in pharmaceutical industry, J Chromatogr Agenerally useful to pharmaceutical industries to facilitateimportance to the pharmaceutical industry in the metabolic

Traylor, Matthew John

2010-01-01T23:59:59.000Z

382

High-Throughput Screen of Natural Product Libraries for Hsp90 Inhibitors  

E-Print Network (OSTI)

and negative controls to make the calculation. Robust statistics [32], which minimizes the effects of outliers on the statistical analysis, were used to calculate the median, robust standard deviation (rSD) and the robust percent coefficient of variance (%r....041 13 rSD). The Microsource compounds were part of a previously published screen [29] that had a Z-factor of 0.62 0.09. The Z-factors for the TimTec and Analyticon screens were 0.77 0.18 and 0.64 0.14, respectively. The %rCV for the screens...

Davenport, Jason; Blach, Maurie; Galam, Lakshmi; Girgis, Antwan; Hall, Jessica; Blagg, Brian S. J.; Matts, Robert L.

2014-03-03T23:59:59.000Z

383

Antibody-functionalized nanoporous surfaces enable high throughput specific cell capture  

E-Print Network (OSTI)

Adhesion-based cell capture on surfaces in microfluidic devices forms the basis of numerous biomedical diagnostics and in vitro assays. Solid surface microfluidic platforms have been widely explored for biomedical diagnostics ...

Mittal, Sukant

2012-01-01T23:59:59.000Z

384

Characterization and High Throughput Analysis of Metal Hydrides for Hydrogen Storage.  

E-Print Network (OSTI)

??Efficient hydrogen storage is required for fuel cell vehicles to be competitive with those driven by internal combustion engines. Current methods of storage such as (more)

Barcelo, Steven James

2009-01-01T23:59:59.000Z

385

High-throughput microfluidic single-cell RT-qPCR  

Science Journals Connector (OSTI)

...1, 2). Planar silicon molds were defined by photolithography, using photomasks designed with CAD software (AutoCAD, Autodesk Inc.) and printed on transparency films at a resolution of 20,000 dots per inch (CAD/Art services). The "control...

Adam K. White; Michael VanInsberghe; Oleh I. Petriv; Mani Hamidi; Darek Sikorski; Marco A. Marra; James Piret; Samuel Aparicio; Carl L. Hansen

2011-01-01T23:59:59.000Z

386

Application of High Throughput Pretreatment and Co-Hydrolysis System to Thermochemical  

E-Print Network (OSTI)

and growing energy demands, as well as to reduce the environmental impacts associated with production to biofuels and other biomaterials by a number of routes (Himmel et al., 2007). To produce biofuels. Wyman Contract grant sponsor: Office of Biological and Environmental Research Contract grant sponsor

California at Riverside, University of

387

Pathway-centric approaches to the analysis of high-throughput genomics data.  

E-Print Network (OSTI)

??In the last decade, molecular biology has expanded from a reductionist view to a systems-wide view that tries to unravel the complex interactions of cellular (more)

Hnzelmann, Sonja, 1981-

2012-01-01T23:59:59.000Z

388

E-Print Network 3.0 - antileishmanial high-throughput drug Sample...  

NLE Websites -- All DOE Office Websites (Extended Search)

antileishmanial and antitrypanosomal Source: Redi, Peter - Institute of Organic Chemistry, Universitt Zrich Collection: Chemistry 14 FUTURE PROSPECTS FOR CHAGAS' DISEASE...

389

Attendees list from the U.S. Department of Energy's High Throughput...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Larry Blair DOE Tom Boussie Symyx Technologies Bob Bowman JPL Larry Cook NIST Alan Cooper Air Products Kristin Deason Sentech Pete DeSanto Air Products R. Greg Downing NIST Mike...

390

High-Throughput Chemical Screening for Antivirulence Developmental Phenotypes in Trypanosoma brucei  

Science Journals Connector (OSTI)

...S. A. 108 :10568-10573. doi: 10.1073/pnas.1105622108 . 13. ET Kamau , AR Srinivasan, MJ Brown, MG Fair, EJ Caraher, and JP Boyle. 2012. A focused small-molecule screen identifies 14 compounds with distinct effects on Toxoplasma gondii...

Paula MacGregor; Alasdair Ivens; Steven Shave; Iain Collie; David Gray; Manfred Auer; Keith R. Matthews

2014-01-17T23:59:59.000Z

391

Characterization of Diversity in Toxicity Mechanism Using in Vitro Cytotoxicity Assays in Quantitative High Throughput Screening  

Science Journals Connector (OSTI)

Rat renal proximal tubule cells were freshly isolated from the kidneys of six male Harlan SpragueDawley rats at age of 5660 days and weight of 220250 g by In Vitro ADMET Laboratories, LLC (Rockville, MD). ... The overall active rate for the caspase assays is significantly lower than that of the cell viability assays, which ranged from 4 to 11% for class 1a, 1b, and 2a compounds (720% for class 13). ...

Ruili Huang; Noel Southall; Ming-Hsuang Cho; Menghang Xia; James Inglese; Christopher P. Austin

2008-02-19T23:59:59.000Z

392

Nanomolar-scale high-throughput chemistry for the synthesis of complex molecules  

Science Journals Connector (OSTI)

...Kuvelkar R. Hodgson R. Hyde L. A. Cox K. Favreau L. Parker E. M. Greenlee W. J. , Discovery of an orally available, brain penetrant BACE1 inhibitor that affords robust CNS A{beta} reduction . ACS Med. Chem. Lett. 3 , 897 902 ( 2012...

Alexander Buitrago Santanilla; Erik L. Regalado; Tony Pereira; Michael Shevlin; Kevin Bateman; Louis-Charles Campeau; Jonathan Schneeweis; Simon Berritt; Zhi-Cai Shi; Philippe Nantermet; Yong Liu; Roy Helmy; Christopher J. Welch; Petr Vachal; Ian W. Davies; Tim Cernak; Spencer D. Dreher

393

High-throughput respirometric assay identifies predictive toxicophore of mitochondrial injury  

SciTech Connect

Many environmental chemicals and drugs negatively affect human health through deleterious effects on mitochondrial function. Currently there is no chemical library of mitochondrial toxicants, and no reliable methods for predicting mitochondrial toxicity. We hypothesized that discrete toxicophores defined by distinct chemical entities can identify previously unidentified mitochondrial toxicants. We used a respirometric assay to screen 1760 compounds (5 ?M) from the LOPAC and ChemBridge DIVERSet libraries. Thirty-one of the assayed compounds decreased uncoupled respiration, a stress test for mitochondrial dysfunction, prior to a decrease in cell viability and reduced the oxygen consumption rate in isolated mitochondria. The mitochondrial toxicants were grouped by chemical similarity and two clusters containing four compounds each were identified. Cheminformatic analysis of one of the clusters identified previously uncharacterized mitochondrial toxicants from the ChemBridge DIVERSet. This approach will enable the identification of mitochondrial toxicants and advance the prediction of mitochondrial toxicity for both drug discovery and risk assessment. - Highlights: Respirometric assay conducted in RPTC to create mitochondrial toxicant database. Chemically similar mitochondrial toxicants aligned as mitochondrial toxicophores Mitochondrial toxicophore identifies five novel mitochondrial toxicants.

Wills, Lauren P. [MitoHealth Inc., Charleston, SC 29403 (United States); Beeson, Gyda C.; Trager, Richard E.; Lindsey, Christopher C. [Department of Drug Discovery and Biomedical Sciences, Medical University of South Carolina, Charleston, SC 29425 (United States); Beeson, Craig C. [MitoHealth Inc., Charleston, SC 29403 (United States); Peterson, Yuri K. [Department of Drug Discovery and Biomedical Sciences, Medical University of South Carolina, Charleston, SC 29425 (United States); Schnellmann, Rick G., E-mail: schnell@musc.edu [Department of Drug Discovery and Biomedical Sciences, Medical University of South Carolina, Charleston, SC 29425 (United States); Ralph H. Johnson VA Medical Center, Charleston, SC 29401 (United States)

2013-10-15T23:59:59.000Z

394

High Throughput Identification, Purification and Structural Characterization of Water Soluble Protein Complexes in Desulfovibrio vulgaris  

SciTech Connect

Our scheme for the tagless purification of water soluble complexes. 10 g of protein from a crude bacterial extract is first fractionated by ammonium sulfate precipitation and then by a series of chromatographic steps: anion exchange (IEX), hydrophobic interaction (HIC), and finally size exclusion (Gel Filtration). Fractions from the last chromatography step are trypsin digested and peptides labeled with iTRAQ reagents to allow multiplexing and quantitation during mass spectrometric analysis. Elution profiles of identified proteins are then subjected to clustering analysis.

Dong,, Ming; Han, Bong-Gyoon; Liu, Hui-Hai; Malik, J.; Geller, Jil; Yang, Li; Choi, M.; Chandonia, John-Marc; Arbelaez, Pablo; Sterling, H. J.; Typke, Dieter; Shatsky, Max; Brenner, Steve; Fisher, Susan; Williams, Evan; Szakal, Evelin; Allen, S.; Hall, S. C.; Hazen, Terry; Witkowska, H. E.; Jin, Jiming; Glaeser, Robert; Biggin, Mark

2010-05-17T23:59:59.000Z

395

Development of a high throughput 3D perfused liver tissue bioreactor  

E-Print Network (OSTI)

This thesis describes the development of a device designed for culturing liver tissue in a 3D perfused environment. Cells form tissue inside miniature channels of a scaffold, and the tissue is perfused with culture medium ...

Inman, Samuel Walker

2006-01-01T23:59:59.000Z

396

Discovery of Novel Targets for Aberrant Methylation in Pancreatic Carcinoma Using High-Throughput Microarrays  

Science Journals Connector (OSTI)

...Microarrays 1 Norihiro Sato Noriyoshi Fukushima Anirban Maitra Hiroyuki Matsubayashi...5-CTCTGTTTAGCACTGATAATG-3 (forward) and 5-TTTATTAGACTTGAGCTGATTC-3...5-CGGGAGATCAAGCAGAATG-3 (forward) and 5-AACGGCCTCGTTGTACTTG-3...61: 8540-8546, 2001. 5 Fukushima N., Sato N., Ueki T...

Norihiro Sato; Noriyoshi Fukushima; Anirban Maitra; Hiroyuki Matsubayashi; Charles J. Yeo; John L. Cameron; Ralph H. Hruban; and Michael Goggins

2003-07-01T23:59:59.000Z

397

Improved High Maximum Stable Throughput FCFS Tree Algorithms with Interference Cancellation  

E-Print Network (OSTI)

Middelheimlaan 1 B-2020 Antwerp, Belgium ABSTRACT Tree algorithms form a well researched class of collision res-detection mechanisms). In point-to- multipoint access networks, such as DVB-RCS satellite net- works and hybrid, Mikhailov and Vvedenskaya [12]. These algorithms were the first to have a provable MST above zero. Afterward

398

E-Print Network 3.0 - aureus strains high-throughput Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

has been... . Staphylococcus aureus is a major human pathogen, and with ... Source: Buckling, Angus - Department of Zoology, University of Oxford Collection: Biology and Medicine...

399

Using Clustering Techniques to Improve Hit Selection in High-Throughput Screening  

E-Print Network (OSTI)

control. This makes the correct identification of active compounds quite difficult. The incoherencies and Makarenkov,7 and Makarenkov et al.8,9 Another factor that influences the identification of active compounds plate or in the bulk of the data). This method is not statistically justified and can lead to some

Makarenkov, Vladimir

400

Predicting gene function through systematic analysis and quality assessment of high-throughput data  

Science Journals Connector (OSTI)

......Fraser, A.G., Dong, Y., Poulin, G., Durbin, R., Gotta...concentration was then adjus-ted to approximately 1 106cells...locations had been permit-ted, the IC of the localization...Fraser,A.G., Dong,Y., Poulin,G., Durbin,R., Gotta......

Patrick Kemmeren; Thessa T. J. P. Kockelkorn; Theo Bijma; Rogier Donders; Frank C. P. Holstege

2005-04-01T23:59:59.000Z

Note: This page contains sample records for the topic "integrated high throughput" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


401

Learning from the Data:? Mining of Large High-Throughput Screening Databases  

Science Journals Connector (OSTI)

We developed a data mining approach based on an algorithm called ontology-based pattern identification (OPI) and applied it to our in-house HTS database. ... In an effort to derive relationships between anticancer compounds and biological targets, Weinstein and colleagues employed a clustered image map (CIM) approach based on compound and activity profile clustering. ...

S. Frank Yan; Frederick J. King; Yun He; Jeremy S. Caldwell; Yingyao Zhou

2006-09-28T23:59:59.000Z

402

WHAM: A High-throughput Sequence Alignment Method Yinan Li Allison Terrell Jignesh M. Patel  

E-Print Network (OSTI)

-1-4503-0661-4/11/06 ...$10.00. only a small portion (called a "read") of the genome. The human genome project delivered its anniversary of the sequencing of the first human genome [1, 21]. This key scientific discovery has been to drug discovery and drug design for personal- ized medicine. A crucial part of this first human genome

Patel, Jignesh

403

MCAM: Multiple Clustering Analysis Methodology for Deriving Hypotheses and Insights from High-Throughput Proteomic Datasets  

E-Print Network (OSTI)

Advances in proteomic technologies continue to substantially accelerate capability for generating experimental data on protein levels, states, and activities in biological samples. For example, studies on receptor tyrosine ...

Naegle, Kristen Marie

404

High-throughput microfluidic single-cell RT-qPCR  

Science Journals Connector (OSTI)

...showed that on-chip analysis provides improved sensitivity...evaluated the efficiency and reliability of on-chip cell processing...followed by washing and analysis using a chemical lysis...creating isolated reactors combining the cell-capture...For mRNA digital PCR analysis cells were washed...

Adam K. White; Michael VanInsberghe; Oleh I. Petriv; Mani Hamidi; Darek Sikorski; Marco A. Marra; James Piret; Samuel Aparicio; Carl L. Hansen

2011-01-01T23:59:59.000Z

405

Inch-Scale High Throughput Metrology of Graphene and Patterned Graphene Oxide  

E-Print Network (OSTI)

Strength of Monolayer Graphene Science 2008 321, 385-388. 5.Novoselov, K. S. The rise of graphene Nature 2007 6 183-191.A. Thermal properties of graphene and nanostructured carbon

Pleskot, Dennis

2013-01-01T23:59:59.000Z

406

High-Throughput in vivo Genetic and Drug Screening Using Femtosecond Laser Microsurgery and Microfluidics  

Science Journals Connector (OSTI)

We developed microfluidic devices, imaging algorithms and femtosecond laser microsurgery technologies to manipulate large numbers of small-animals on a single chip for sub-cellular...

Rohde, Christopher B; Zeng, Fei; Gilleland, Coddy; Gonzalez-Rubio, Ricardo; Angel, Matthew; Yanik, Mehmet F

407

Polymer microfluidic device for high-throughput single-cell encapsulation, lysis, and biological assay  

E-Print Network (OSTI)

rheology through microfluidics, Advanced Materials, vol.Berthier and P. Silberzan, Microfluidics for Biotechnology.A. P. Lee, Droplet microfluidics, Lab on a Chip, vol. 8,

Brackbill, Timothy Peter

2012-01-01T23:59:59.000Z

408

Characterization and High Throughput Analysis of Metal Hydrides for Hydrogen Storage  

E-Print Network (OSTI)

Metal Hydrides for Hydrogen Storage by Steven James BarceloMetal Hydrides for Hydrogen Storage by Steven James BarceloCo-chair Efficient hydrogen storage is required for fuel

Barcelo, Steven James

2009-01-01T23:59:59.000Z

409

High-Throughput/Combinatorial Techniques in Hydrogen Storage Materials R&D (presentation)  

Energy.gov (U.S. Department of Energy (DOE))

Meeting Background, Purpose and Agenda presented at the U.S. Department of Energy's Hydrogen Storage Meeting held June 26, 2007 in Bethesda, Maryland.

410

High-throughput experimental and computational tools for exploring immunity and the microbiome  

E-Print Network (OSTI)

Humans live in association with trillions of microbes and yet we know remarkably little about their symbiotic relationship. The role these microorganisms have in humans has been characterized only in the case of few bacteria ...

Papa, Eliseo

2012-01-01T23:59:59.000Z

411

Weighted poolingpractical and cost-effective techniques for pooled high-throughput sequencing  

Science Journals Connector (OSTI)

......Sophisticated pooling designs require belief-propagation...compressed sensing design remains an open one...strategies is based on crossing information between...problem along the pipeline does not influence...a first step in a road that may eventually utilize more complex designs to a greater benefit......

David Golan; Yaniv Erlich; Saharon Rosset

2012-06-15T23:59:59.000Z

412

ADAPTIVE MATRIX METRICS FOR ATTRIBUTE DEPENDENCE ANALYSIS IN DIFFERENTIAL HIGH-THROUGHPUT DATA  

E-Print Network (OSTI)

. Corresponding author email: stricker@ipk-gatersleben.de ABSTRACT Data-driven metric adaptation is proposed descent method [7]. 2. METHOD ­ MATRIX LEARNING As input q-dimensional row vectors x R1?q are as- sumed

Biehl, Michael

413

PDMS-based microfluidic platforms for chemical analysis and high-throughput screening.  

E-Print Network (OSTI)

??Microfluidics, as a new interdisciplinary field, holds the promise to offer better solutionsfor analytical chemistry, bioscience, and material science etc. However, microfluidics is still in (more)

Zhou, Jianhua

2011-01-01T23:59:59.000Z

414

Investigation of Extra-Large Pore Zeolite Synthesis by a High-Throughput Approach  

Science Journals Connector (OSTI)

A.C. thanks the project consolider Ingenio MULTICAT for financial support. ... Klein, J.; Lehmann, C. W.; Schmidt, H. W.; Maier, W. F. Angew. ...

Jiuxing Jiang; Yan Xu; Peng Cheng; Qiming Sun; Jihong Yu; Avelino Corma; Ruren Xu

2011-10-12T23:59:59.000Z

415

The Development of a High-throughput Microdroplet Bioreactor Device for Microbial Studies  

E-Print Network (OSTI)

Current PCR Polymerase Chain Reaction MOS-FET Metal-Oxide-Semiconductor Field-Effect Transistor BSA Bovine Serum Albumin GFP Green Fluorescent Protein RFP Red Fluorescent Protein LED Light Emitting Diode PMT Photomultiplier Tubes...

Guzman, Adrian

2012-10-19T23:59:59.000Z

416

Polymers with hydro-responsive topography identified using high throughput AFM of an acrylate microarray  

E-Print Network (OSTI)

Atomic force microscopy has been applied to an acrylate polymer microarray to achieve a full topographic characterisation. This process discovered a small number of hydro-responsive materials created from monomers with ...

Hook, Andrew L.

417

High-Throughput and Combinatorial Screening of Hydrogen Storage Materials (presentation)  

Energy.gov (U.S. Department of Energy (DOE))

Presented at the U.S. Department of Energy's Hydrogen Storage Meeting held June 26, 2007 in Bethesda, Maryland.

418

Generation of expression vectors for high-throughput functional analysis of target genes in Schizosaccharomyces pombe  

Science Journals Connector (OSTI)

An immediate challenge in the post-genomic era is to assign a biological functions to proteins unraveled by genome analysis. This report is based on studies conducted using Schizosaccharomyces pombe, a simple mod...

Jiwon Ahn; Chung-Hae Choi; Chang-Mo Kang; Chun-Ho Kim

2009-12-01T23:59:59.000Z

419

High-throughput Characterization of Porous Materials Using Graphics Processing Units  

E-Print Network (OSTI)

framework atoms. Using a parallel flood fill CPU algorithm,segmentation using a parallel flood fill (also known as seeddescribed in Ref. 39 Flood fill is a recursive algorithm to

Kim, Jihan

2013-01-01T23:59:59.000Z

420

Outbreak Investigation Using High-Throughput Genome Sequencing within a Diagnostic Microbiology Laboratory  

Science Journals Connector (OSTI)

...positive culture to the completion of sequencing (prior...bioMerieux). Aside from the index case, three out of...BPH0532, BPH0657 [index case], and BPH0658...culture to sequence completion (prior to data analysis...positive culture to completion of sequencing (prior...

Norelle L. Sherry; Jessica L. Porter; Torsten Seemann; Andrew Watkins; Timothy P. Stinear; Benjamin P. Howden

2013-02-13T23:59:59.000Z

Note: This page contains sample records for the topic "integrated high throughput" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


421

Characterization and High Throughput Analysis of Metal Hydrides for Hydrogen Storage  

E-Print Network (OSTI)

affect the fundamental changes to electronic structure thatunderstood. A fundamental study of the electronic structure

Barcelo, Steven James

2009-01-01T23:59:59.000Z

422

High-Throughput Screening for Functional Adenosine to Inosine RNA Editing Systems  

E-Print Network (OSTI)

and Peter A. Beal* Department of Chemistry, University of Utah, 315 South 1400 East, Salt Lake City, Utah sequence changes to maintain an open reading frame and create a stop codon *Corresponding author, beal

Beal, Peter A.

423

Systems Integration  

Energy.gov (U.S. Department of Energy (DOE))

Through the SunShot Initiative, the U.S. Department of Energy (DOE) supports the development of innovative, cost-effective solutions that allow increasing amounts of solar energy to integrate...

424

Integration elements  

Science Journals Connector (OSTI)

Market-based integration is simple: Do whatever you want, the rest is up to the market. This model of the individual and its relation to others best suits the logic of the consumer society ?self-orientation an...

Dr. Eric Dieth

2011-01-01T23:59:59.000Z

425

Procurement Integrity  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

employment with certain bidders or offerors. This chapter is intended to act as a primer for all DOE employees on issues related to procurement integrity. As such, not all...

426

A Semiautomated Framework for Integrating Expert Knowledge into Disease Marker Identification  

SciTech Connect

Background. The availability of large complex data sets generated by high throughput technologies has enabled the recent proliferation of disease biomarker studies. However, a recurring problem in deriving biological information from large data sets is how to best incorporate expert knowledge into the biomarker selection process. Objective. To develop a generalizable framework that can incorporate expert knowledge into data-driven processes in a semiautomated way while providing a metric for optimization in a biomarker selection scheme. Methods. The framework was implemented as a pipeline consisting of five components for the identification of signatures from integrated clustering (ISIC). Expert knowledge was integrated into the biomarker identification process using the combination of two distinct approaches; a distance-based clustering approach and an expert knowledge-driven functional selection. Results. The utility of the developed framework ISIC was demonstrated on proteomics data from a study of chronic obstructive pulmonary disease (COPD). Biomarker candidates were identified in a mouse model using ISIC and validated in a study of a human cohort. Conclusions. Expert knowledge can be introduced into a biomarker discovery process in different ways to enhance the robustness of selected marker candidates. Developing strategies for extracting orthogonal and robust features from large data sets increases the chances of success in biomarker identification.

Wang, Jing; Webb-Robertson, Bobbie-Jo M.; Matzke, Melissa M.; Varnum, Susan M.; Brown, Joseph N.; Riensche, Roderick M.; Adkins, Joshua N.; Jacobs, Jon M.; Hoidal, John R.; Scholand, Mary Beth; Pounds, Joel G.; Blackburn, Michael R.; Rodland, Karin D.; McDermott, Jason E.

2013-10-01T23:59:59.000Z

427

Flow-Through Microfluidic Device for High-Efficiency Transfection of Mammalian Cells through Combined Microelectroporation and Sonoporation  

E-Print Network (OSTI)

In this study we are presenting a proof-of-concept microfluidic device that simultaneously applies the conditions required for microelectroporation and micro-sonoporation in a flow-through fashion that allows for high throughput, high efficiency...

Longsine, Whitney Leigh

2012-07-16T23:59:59.000Z

428

NREL: Energy Systems Integration - Integrated Deployment Workshop  

NLE Websites -- All DOE Office Websites (Extended Search)

Integrated Deployment Workshop Integrated Deployment Workshop The Energy Systems Integration Facility workshop, Integrated Deployment, was held August 21 - 23, 2012 at the National Renewable Energy Laboratory in Golden, Colorado. Each day of the workshop, which included a tour of the Energy Systems Integration Facility, focused on a different topic: Day 1: Utility-Scale Renewable Integration Day 2: Distribution-Level Integration Day 3: Isolated and Islanded Grid Systems The agenda and presentations from the workshop are below. Agenda Energy Systems Integration Facility Overview ESIF Technology Partnerships Integrated Deployment Model Integrated Deployment and the Energy Systems Integration Facility: Workshop Proceedings Printable Version Energy Systems Integration Home Research & Development

429

high  

Gasoline and Diesel Fuel Update (EIA)

0 0 Highlights International Oil Markets Prices. We have raised our world oil price projection by about $2 per barrel for this month because of assumed greater compliance by OPEC to targeted cuts, especially for the second quarter of 2000 (Figure 1). The expected decline in world petroleum inventories continues (Figure 2), and, given the generally stiff resolve of OPEC members to maintain production cuts, any sign of a turnaround in stocks may be postponed until later this year than previously assumed (Q3 instead of Q2). Our current estimate for the average import cost this past January is now $25 per barrel, a nearly $15-per-barrel increase from January 1999. Crude oil prices are expected to remain at relatively high levels for the first half of 2000, but

430

High-Performance Control of Two Three-Phase Permanent-Magnet Synchronous Machines in an Integrated Drive for Automotive Applications  

SciTech Connect

The closed-loop control of an integrated dual AC drive system is presented to control two three-phase permanent-magnet motors. A five-leg inverter is employed in the drive system; three of the inverter legs are for a main traction motor, but only two are needed for a three-phase auxiliary motor by utilizing the neutral point of the traction motor. An integrated drive with reduced component count is therefore achieved by eliminating one inverter leg and its gate drivers. A modified current control scheme based on the rotor flux orientation principle is presented. Simulation and experimental results are included to verify the independent control capability of the integrated drive.

Tang, Lixin [ORNL; Su, Gui-Jia [ORNL

2008-01-01T23:59:59.000Z

431

Cloning of the Arabidopsis RSF1 Gene by Using a Mapping Strategy Based on High-Density DNA Arrays and Denaturing High-Performance Liquid Chromatography  

Science Journals Connector (OSTI)

...both are amenable to high-throughput automation, which is an essential prerequisite in...tairpub@ftp.arabidopsis.org/home/tair/Software">ftp://tairpub:tairpub@ftp.arabidopsis.org/home/tair/Software. Marker scores...

Jamie I. Spiegelman; Michael N. Mindrinos; Christian Fankhauser; Daniel Richards; Jason Lutes; Joanne Chory; Peter J. Oefner

432

A high performance differential amplifier through the direct monolithic integration of InP HBTs and Si CMOS on silicon substrates  

E-Print Network (OSTI)

We present results on the direct monolithic integration of III-V devices and Si CMOS on a silicon substrate. InP HBTs (0.5 times 5 um2 emitter) with ft and fmax > 200 GHz were grown directly in windows adjacent to CMOS ...

Bulsara, Mayank

433

integr~1  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

7 7 AUDIT REPORT THE U.S. DEPARTMENT OF ENERGY' S MANAGEMENT OF RESEARCH AND DEVELOPMENT INTEGRATION MARCH 1998 U.S. DEPARTMENT OF ENERGY OFFICE OF INSPECTOR GENERAL OFFICE OF AUDIT SERVICES DEPARTMENT OF ENERGY Washington, DC 20585 MEMORANDUM FOR THE SECRETARY FROM: Gregory H. Friedman Principal Deputy Inspector General SUBJECT: INFORMATION : Audit Report on "Audit of the Department of Energy's Management of Research and Development Integration" BACKGROUND The Congress, independent task forces, and advisory groups have pointed out the need for the Department to improve its integration of research and development (R&D) projects. In the past, R&D management was carried out by different program offices with the research being

434

Increasing throughput of multiplexed electrical bus in pipe-lined architecture  

DOE Patents (OSTI)

Techniques are disclosed for increasing the throughput of a multiplexed electrical bus by exploiting available pipeline stages of a computer or other system. For example, a method for increasing a throughput of an electrical bus that connects at least two devices in a system comprises introducing at least one signal hold stage in a signal-receiving one of the two devices, such that a maximum frequency at which the two devices are operated is not limited by a number of cycles of an operating frequency of the electrical bus needed for a signal to propagate from a signal-transmitting one of the two devices to the signal-receiving one of the two devices. Preferably, the signal hold stage introduced in the signal-receiving one of the two devices is a pipeline stage re-allocated from the signal-transmitting one of the two devices.

Asaad, Sameh; Brezzo, Bernard V; Kapur, Mohit

2014-05-27T23:59:59.000Z

435

High-Tech Means High-Efficiency: The Business Case for EnergyManagement in High-Tech Industries  

SciTech Connect

In the race to apply new technologies in ''high-tech'' facilities such as data centers, laboratories, and clean rooms, much emphasis has been placed on improving service, building capacity, and increasing speed. These facilities are socially and economically important, as part of the critical infrastructure for pharmaceuticals,electronics, communications, and many other sectors. With a singular focus on throughput, some important design issues can be overlooked, such as the energy efficiency of individual equipment (e.g., lasers, routers and switches) as well as the integration of high-tech equipment into the power distribution system and the building envelope. Among technology-based businesses, improving energy efficiency presents an often untapped opportunity to increase profits, enhance process control,maximize asset value, improve the work place environment, and manage a variety of business risks. Oddly enough, the adoption of energy efficiency improvements in this sector lags behind many others. As a result, millions of dollars are left on the table with each year ofoperation.

Shanshoian, Gary; Blazek, Michele; Naughton, Phil; Seese, RobertS.; Mills, Evan; Tschudi, William

2005-11-15T23:59:59.000Z

436

A novel polymeric microelectrode array for highly parallel, long-term neuronal culture and stimulation  

E-Print Network (OSTI)

Cell-based high-throughput screening is emerging as a disruptive technology in drug discovery; however, massively parallel electrical assaying of neurons and cardiomyocites has until now been prohibitively expensive. To ...

Talei Franzesi, Giovanni

2008-01-01T23:59:59.000Z

437

Optical receiver techniques for integrated photonic links  

E-Print Network (OSTI)

Integrated photonics has emerged as an I/O technology set to disrupt the communication fabric of many-core computer systems. The optical technology uses wavelength-division-multiplexing and a high degree of integration in ...

Georgas, Michael S. (Michael Stephen)

2014-01-01T23:59:59.000Z

438

Engineering High Performance Service-Oriented Pipeline Applications with MeDICi  

SciTech Connect

The pipeline software architecture pattern is commonly used in many application domains to structure a software system. A pipeline comprises a sequence of processing steps that progressively transform data to some desired outputs. As pipeline-based systems are required to handle increasingly large volumes of data and provide high throughput services, simple scripting-based technologies that have traditionally been used for constructing pipelines do not scale. In this paper we describe the MeDICI Integration Framework (MIF), which is specifically designed for building flexible, efficient and scalable pipelines that exploit distributed services as elements of the pipeline. We explain the core runtime and development infrastructures that MIF provides, and demonstrate how MIF has been used in two complex applications to improve performance and modifiability.

Gorton, Ian; Wynne, Adam S.; Liu, Yan

2011-01-07T23:59:59.000Z

439

Arrays of high-aspect ratio microchannels for high-throughput isolation of circulating tumor cells (CTCs)  

Science Journals Connector (OSTI)

Microsystem-based technologies are providing new opportunities in the area of in vitro diagnostics due to their ability to provide process automation enabling point-of-care operation. As an example, microsystems used for the isolation and analysis of ...

Mateusz L. Hupert, Joshua M. Jackson, Hong Wang, Ma?gorzata A. Witek, Joyce Kamande, Matthew I. Milowsky, Young E. Whang, Steven A. Soper

2014-10-01T23:59:59.000Z

440

NREL: Transmission Grid Integration - Wind Integration Datasets  

NLE Websites -- All DOE Office Websites (Extended Search)

Wind Integration Datasets The Wind Integration Datasets provide energy professionals with a consistent set of wind profiles for the eastern United States and the western United...

Note: This page contains sample records for the topic "integrated high throughput" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


441

CASE STUDY: From Three to One: Integrating a High Performance Work Organization Process, Lean Production, and Activity Based Costing Change Initiatives  

E-Print Network (OSTI)

In 1997 Boeings Wichita Division and the International Association of Machinists and Aerospace Workers agreed to launch a High Performance Work Organization (HPWO) process. This followed the introduction of a Lean ...

Kochan, Thomas A.

2000-01-01T23:59:59.000Z

442

Integrated Omics in Systems Biology: The New Frontier for Environmental Biotechnology  

SciTech Connect

Environmental biotechnology encompasses a wide range of characterization, monitoring and control for bioenergy and bioremediation technologies that are based on biological processes. Recent breakthroughs in our understanding of biogeochemical processes and genomics are leading to exciting new and cost effective ways to monitor and manipulate the environment and potentially produce bioenergy fuels as we also cleanup the environment. Indeed, our ability to sequence an entire microbial genome in just a few hours is leading to similar breakthroughs in characterizing proteomes, metabolomes, phenotypes, and fluxes for organisms, populations, and communities. Understanding and modeling functional microbial community structure and stress responses in subsurface environments has tremendous implications for our fundamental understanding of biogeochemistry and the potential for making biofuel breakthroughs. Monitoring techniques that inventory and monitor terminal electron acceptors and electron donors, enzyme probes that measure functional activity in the environment, functional genomic microarrays, phylogenetic microarrays, metabolomics, proteomics, and quantitative PCR are also being rapidly adapted for studies in environmental biotechnology. Integration of all of these new high throughput techniques using the latest advances in bioinformatics and modeling will enable break-through science in environmental biotechnology. A review of these techniques with examples from field studies and lab simulations will be discussed.

Hazen, Terry C.

2008-08-12T23:59:59.000Z

443

Final report for %22High performance computing for advanced national electric power grid modeling and integration of solar generation resources%22, LDRD Project No. 149016.  

SciTech Connect

Design and operation of the electric power grid (EPG) relies heavily on computational models. High-fidelity, full-order models are used to study transient phenomena on only a small part of the network. Reduced-order dynamic and power flow models are used when analysis involving thousands of nodes are required due to the computational demands when simulating large numbers of nodes. The level of complexity of the future EPG will dramatically increase due to large-scale deployment of variable renewable generation, active load and distributed generation resources, adaptive protection and control systems, and price-responsive demand. High-fidelity modeling of this future grid will require significant advances in coupled, multi-scale tools and their use on high performance computing (HPC) platforms. This LDRD report demonstrates SNL's capability to apply HPC resources to these 3 tasks: (1) High-fidelity, large-scale modeling of power system dynamics; (2) Statistical assessment of grid security via Monte-Carlo simulations of cyber attacks; and (3) Development of models to predict variability of solar resources at locations where little or no ground-based measurements are available.

Reno, Matthew J.; Riehm, Andrew Charles; Hoekstra, Robert John; Munoz-Ramirez, Karina; Stamp, Jason Edwin; Phillips, Laurence R.; Adams, Brian M.; Russo, Thomas V.; Oldfield, Ron A.; McLendon, William Clarence, III; Nelson, Jeffrey Scott; Hansen, Clifford W.; Richardson, Bryan T.; Stein, Joshua S.; Schoenwald, David Alan; Wolfenbarger, Paul R.

2011-02-01T23:59:59.000Z

444

Design and Analysis of High-Performance Air-Cooled Heat Exchanger with an Integrated Capillary-Pumped Loop Heat Pipe  

E-Print Network (OSTI)

We report the design and analysis of a high-power air-cooled heat exchanger capable of dissipating over 1000 W with 33 W of input electrical power and an overall thermal resistance of less than 0.05 K/W. The novelty of the ...

McCarthy, Matthew

445

Human Herpesvirus 6 Chromosomal Integration in Immunocompetent Patients Results in High Levels of Viral DNA in Blood, Sera, and Hair Follicles  

Science Journals Connector (OSTI)

...High Levels of Viral DNA in Blood, Sera, and Hair Follicles Katherine N. Ward 1 Corresponding author. Mailing address: Centre...478-484. 3 Clark, D. A., M. Ait-Khaled, A. C. Wheeler, I. M. Kidd, J. E. McLaughlin, M. A. Johnson, P...

Katherine N. Ward; Hoe Nam Leong; Elisabeth P. Nacheva; Julie Howard; Claire E. Atkinson; Nicholas W. S. Davies; Paul D. Griffiths; Duncan A. Clark

2006-04-01T23:59:59.000Z

446

Integrated optic/nanofluidic detection device with plasmonic readout  

E-Print Network (OSTI)

Integrated lab-on-a-chip devices provide the promise of many benefits in many application areas. A low noise, high resolution, high sensitivity integrated optical microfluidic device would not only improve the capabilities ...

Varsanik, Jonathan S

2011-01-01T23:59:59.000Z

447

LTCP-RC: RTT compensation technique to scale high-speed protocol in high RTT links  

E-Print Network (OSTI)

by large link delays and high RTTs, LTCP-RC makes the LTCP protocol more scalable. Ack-clocked schemes, similar to TCP, suffer performance problems like long convergence time and throughput degradation, when RTT experienced by the flow increases. Also, when...

Jain, Saurabh

2005-11-01T23:59:59.000Z

448

A high-speed, flexible-scanning chemical imaging system using a light-addressable potentiometric sensor integrated with an analog micromirror  

Science Journals Connector (OSTI)

Abstract A semiconductor-based chemical imaging sensor is a type of field-effect, label-free sensing system that can visualize a two-dimensional distribution of concentrations for specific chemical species on a sensor surface. This report presents the development of a high-speed, flexible chemical imaging sensor system using an analog micromirror as a light-addressing setup to scan the light-addressable potentiometric sensor (LAPS) surface from the underside. In the proposed system, a two-axis electrostatic comb-driven micromirror is used to control a modulated laser beam with rapid and tunable scanning capabilities. The position, X- and Y-axis step, direction of movement and speed of the moving laser spot can be arbitrarily defined using the programmed control on the angular rotation of the micromirror. A high-speed spatiotemporal recording of the change in pH at a rate of approximately 16fps (frames per second) using backside illumination has been achieved by the current setup. In addition, a high-resolution chemical image with 200k pixels of a test pattern in a sensor area of 14.5נ10.5mm2 was achieved within 40s. The frequency-dependent photovoltage, photovoltage-reference bias voltage characteristics, and pH sensitivity are also demonstrated and discussed systematically for optimization.

Anirban Das; Tsung-Cheng Chen; Chia-Ming Yang; Chao-Sung Lai

2014-01-01T23:59:59.000Z

449

Device integration for silicon microphotonic platforms  

E-Print Network (OSTI)

Silicon ULSI compatible, high index contrast waveguides and devices provide high density integration for optical networking and on-chip optical interconnects. Four such waveguide systems were fabricated and analyzed: ...

Lim, Desmond Rodney

2000-01-01T23:59:59.000Z

450

Fixed Point Analysis of Single Cell IEEE 802.11e WLANs: Uniqueness, Multistability and Throughput Differentiation  

E-Print Network (OSTI)

Fixed Point Analysis of Single Cell IEEE 802.11e WLANs: Uniqueness, Multistability and Throughput Differentiation Venkatesh Ramaiyan ECE Department Indian Institute of Science Bangalore, India rvenkat@ece.iisc.ernet.in Anurag Kumar ECE Department Indian Institute of Science Bangalore, India anurag@ece.iisc.ernet.in Eitan

Kumar, Anurag

451

Fixed Point Analysis of Single Cell IEEE 802.11e WLANs: Uniqueness, Multistability and Throughput Differentiation  

E-Print Network (OSTI)

Fixed Point Analysis of Single Cell IEEE 802.11e WLANs: Uniqueness, Multistability and Throughput Differentiation Venkatesh Ramaiyan1, Anurag Kumar1, Eitan Altman2 Abstract-- We consider the vector fixed point- bitration InterFrame Space (AIFS) values. We consider balanced and unbalanced solutions of the fixed point

Kumar, Anurag

452

Utility Maximization for Resolving Throughput/Reliability Trade-offs in an Unreliable Network with Multipath Routing  

E-Print Network (OSTI)

Utility Maximization for Resolving Throughput/Reliability Trade-offs in an Unreliable Network can be characterized by some utility function, the goal of balancing competing requirements for each user as well as across different users is to maximize the aggregate utility. The framework assumes

453

Optimal Throughput and Self-adaptability of Robust Real-Time IEEE 802.15.4 MAC for AMI Mesh Network  

Science Journals Connector (OSTI)

A smart grid refers to a modernization of the electricity system that brings intelligence, reliability, efficiency and optimality to the power grid. To provide an automated and widely distributed energy delivery, the smart grid will be branded by a two-way flow of electricity and information system between energy suppliers and their customers. Thus, the smart grid is a power grid that integrates data communication networks which provide the collected and analysed data at all levels in real time. Therefore, the performance of communication systems is so vital for the success of smart grid. Merit to the ZigBee/IEEE802.15.4std low cost, low power, low data rate, short range, simplicity and free licensed spectrum that makes wireless sensor networks (WSNs) the most suitable wireless technology for smart grid applications. Unfortunately, almost all ZigBee channels overlap with wireless local area network (WLAN) channels, resulting in severe performance degradation due to interference. In order to improve the performance of communication systems, this paper proposes an optimal throughput and self-adaptability of ZigBee/IEEE802.15.4std for smart grid.

Hikma Shabani; Musse Mohamud Ahmed; Sheroz Khan; Shahab Ahmed Hameed; Mohamed Hadi Habaebi

2013-01-01T23:59:59.000Z

454

Demonstration of a Novel, Integrated, Multi-Scale Procedure for High-Resolution 3D Reservoir Characterization and Improved CO2-EOR/Sequestration Management, SACROC Unit  

SciTech Connect

The primary goal of this project was to demonstrate a new and novel approach for high resolution, 3D reservoir characterization that can enable better management of CO{sub 2} enhanced oil recovery (EOR) projects and, looking to the future, carbon sequestration projects. The approach adopted has been the subject of previous research by the DOE and others, and relies primarily upon data-mining and advanced pattern recognition approaches. This approach honors all reservoir characterization data collected, but accepts that our understanding of how these measurements relate to the information of most interest, such as how porosity and permeability vary over a reservoir volume, is imperfect. Ideally the data needed for such an approach includes surface seismic to provide the greatest amount of data over the entire reservoir volume of interest, crosswell seismic to fill the resolution gap between surface seismic and wellbore-scale measurements, geophysical well logs to provide the vertical resolution sought, and core data to provide the tie to the information of most interest. These data are combined via a series of one or more relational models to enable, in its most successful application, the prediction of porosity and permeability on a vertical resolution similar to logs at each surface seismic trace location. In this project, the procedure was applied to the giant (and highly complex) SACROC unit of the Permian basin in West Texas, one of the world's largest CO{sub 2}-EOR projects and a potentially world-class geologic sequestration site. Due to operational scheduling considerations on the part of the operator of the field, the crosswell data was not obtained during the period of project performance (it is currently being collected however as part of another DOE project). This compromised the utility of the surface seismic data for the project due to the resolution gap between it and the geophysical well logs. An alternative approach was adopted that utilized a relational model to predict porosity and permeability profiles from well logs at each well location, and a 3D geostatistical variogram to generate the reservoir characterization over the reservoir volume of interest. A reservoir simulation model was built based upon this characterization and history-matched without making significant changes to it, thus validating the procedure. While not the same procedure as originally planned, the procedure ultimately employed proved successful and demonstrated that the general concepts proposed (i.e., data mining and advanced pattern recognition methods) have the flexibility to achieve the reservoir characterization objectives sought even with imperfect or incomplete data.

Scott R. Reeves

2007-09-30T23:59:59.000Z

455

Thermal Control & System Integration  

Energy.gov (U.S. Department of Energy (DOE))

The thermal control and system integration activity focuses on issues such as the integration of motor and power control technologies and the development of advanced thermal control technologies....

456

Distribution Grid Integration  

Energy.gov (U.S. Department of Energy (DOE))

The DOE Systems Integration team funds distribution grid integration research and development (R&D) activities to address the technical issues that surround distribution grid planning,...

457

IEEE Communications Magazine February 20022 Distributed Integrated Circuits  

E-Print Network (OSTI)

Approach to High-Frequency Design 0163-6804/02/$17.00 © 2002 IEEE ABSTRACT Distributed integrated circuits are presented as a methodology to design high-frequency commu- nication building blocks. Distributed circuits be implemented as integrated circuits. The integrated circuit design process is then divided further by defining

Hajimiri, Ali

458

IBM and Johnson Controls Integrated  

E-Print Network (OSTI)

IBM and Johnson Controls Integrated Smarter Building Solution IBM and Johnson Controls make it simpler to reduce energy and operational costs while reducing greenhouse emissions. IBM and Johnson and more. IBM and Johnson Controls work with you to identify high-priority energy consumption areas

459

Residential Buildings Integration Program  

Energy.gov (U.S. Department of Energy (DOE))

Residential Buildings Integration Program Presentation for the 2013 Building Technologies Office's Program Peer Review

460

Microfluidic very large scale integration (mVLSI) with integrated micromechanical valves{  

E-Print Network (OSTI)

Microfluidic very large scale integration (mVLSI) with integrated micromechanical valves{ Ismail40258k Microfluidic chips with a high density of control elements are required to improve device and accessible high-density microfluidic chips, we have fabricated a monolithic PDMS valve architecture

Quake, Stephen R.

Note: This page contains sample records for the topic "integrated high throughput" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


461

HIGHLY AUTOMATED MACROMOLECULAR  

NLE Websites -- All DOE Office Websites (Extended Search)

AUTOMATED MACROMOLECULAR AUTOMATED MACROMOLECULAR CRYSTALLOGRAPHY BEAMLINE (AMX) Group Leader: Dieter Schneider Proposal Team: M. Allaire 1 , L. Berman 1 , M. Chance 2 , W. Hendrickson 3 , A. Héroux 1 , J. Jakoncic 1 , A. Orville 1 , H. Robinson 1 , D. Schneider 1 , W. Shi 2 , A. Soares 1 , V. Stojanoff 1 , R. Sweet 1 1 Brookhaven National Laboratory, 2 Case Western Reserve University, 3 Columbia University MISSION APPLICATIONS AND CAPABILITIES ADDITIONAL INFORMATION * AMX at NSLS-II will provide structural biologists with ready access to an advanced macromolecular crystallography (MX) beamline for the elucidation of structure and function of macromolecular complexes. * Its high flux, tunable energy, and natively small focal spot will make it a crystallographer's preferred beamline. * Its high degree of automation will provide a high throughput

462

Development of High Performance Fluxomics Tools for Microbial Metabolism Analysis  

E-Print Network (OSTI)

,Ph.D. Dept.ofEnergy,Environmental&ChemicalEngineering WashingtonUniversityinSt.Louis Mar5th,2012 #12;Energy Engineering for bioenergy and chemicals Transcriptomics Proteomics FluxomicsMetabolomics #12;Metabolic Flux MicrobesFlux: a web platform for high-throughput model drafting · 13C tracer experiments and computational

Subramanian, Venkat

463

Sponsored by Nanotechnology Seminar Program A Novel 3-Dimensional High-  

E-Print Network (OSTI)

Sponsored by Nanotechnology Seminar Program A Novel 3-Dimensional High- Throughput Assay for Targeting Invasive Cancer Cells Professor Jian Cao Associate Professor of Research Medicine and Director of Cancer Laboratory Division of Cancer Prevention, School of Medicine Stony Brook University ABSTRACT

Fisher, Frank

464

High-speed one-dimensional spatial light modulator for Laser Direct Imaging and other patterning applications  

E-Print Network (OSTI)

High-speed one-dimensional spatial light modulator for Laser Direct Imaging and other patterning developed a one-dimensional high-speed spatial light modulator in cooperation with Micronic Mydata AB of ultraviolet light needs to be combined with high throughput and high precision. Keywords: Laser Direct Imaging

Jonsson, Fredrik

465

Integrating advanced facades into high performance buildings  

E-Print Network (OSTI)

will ultimately become an energy supplier. 2. Integrationand ultimately to energy suppliers. Many of the new

Selkowitz, Stephen E.

2001-01-01T23:59:59.000Z

466

High Power Density Integrated Traction Machine Drive  

Energy.gov (U.S. Department of Energy (DOE))

2011 DOE Hydrogen and Fuel Cells Program, and Vehicle Technologies Program Annual Merit Review and Peer Evaluation

467

Copper wafer bonding in three-dimensional integration  

E-Print Network (OSTI)

Three-dimensional (3D) integration, in which multiple layers of devices are stacked with high density of interconnects between the layers, offers solutions for problems when the critical dimensions in integrated circuits ...

Chen, Kuan-Neng, 1974-

2005-01-01T23:59:59.000Z

468

Managing the integration of technology into the product development pipeline  

E-Print Network (OSTI)

Managing the integration of technology is a complex task in any industry, but especially so in the highly competitive automotive industry. Automakers seek to develop plans to integrate technology into their products such ...

Barretto, Eduardo F., 1971-

2005-01-01T23:59:59.000Z

469

Operating Reserves and Wind Power Integration: An International Comparison; Preprint  

SciTech Connect

This paper provides a high-level international comparison of methods and key results from both operating practice and integration analysis, based on an informal International Energy Agency Task 25: Large-scale Wind Integration.

Milligan, M.; Donohoo, P.; Lew, D.; Ela, E.; Kirby, B.; Holttinen, H.; Lannoye, E.; Flynn, D.; O'Malley, M.; Miller, N.; Eriksen, P. B.; Gottig, A.; Rawn, B.; Gibescu, M.; Lazaro, E. G.; Robitaille, A.; Kamwa, I.

2010-10-01T23:59:59.000Z

470

General linear methods for Volterra integral equations  

Science Journals Connector (OSTI)

We investigate the class of general linear methods of order p and stage order q=p for the numerical solution of Volterra integral equations of the second kind. Construction of highly stable methods based on the Schur criterion is described and examples ... Keywords: Convolution test equation, General linear methods, Linear stability analysis, Order conditions, Volterra integral equations

G. Izzo; Z. Jackiewicz; E. Messina; A. Vecchio

2010-09-01T23:59:59.000Z

471

Microfluidic Large-Scale Integration: The Evolution  

E-Print Network (OSTI)

Microfluidic Large-Scale Integration: The Evolution of Design Rules for Biological Automation, polydimethylsiloxane Abstract Microfluidic large-scale integration (mLSI) refers to the develop- ment of microfluidic, are discussed. Several microfluidic components used as building blocks to create effective, complex, and highly

Quake, Stephen R.

472

High-speed discrimination and sorting of sub-micron particles using a microfluidic device  

E-Print Network (OSTI)

The size- and fluorescence-based sorting of micro- and nano-scale particles suspended in fluid presents a significant and important challenge for both sample analysis and for manufacturing of nanoparticle-based products. Here we demonstrate a disposable microfluidic particle sorter that enables high-throughput, on-demand counting and binary sorting of sub-micron particles and cells, using either fluorescence or an electrically-based determination of particle size. Size-based sorting uses a resistive pulse sensor integrated on-chip, while fluorescence-based discrimination is achieved using on-the-fly optical image capture and analysis. Following detection and analysis, the individual particles are deflected using a pair of piezoelectric actuators, directing the particles into one of two desired output channels; the main flow goes into a third waste channel. The integrated system can achieve sorting fidelities of better than 98\\%, and the mechanism can successfully count and actuate, on demand, more than 60,000...

Rajauria, Sukumar; Gottstein, Claudia; Cleland, Andrew N

2014-01-01T23:59:59.000Z

473

High-speed discrimination and sorting of sub-micron particles using a microfluidic device  

E-Print Network (OSTI)

The size- and fluorescence-based sorting of micro- and nano-scale particles suspended in fluid presents a significant and important challenge for both sample analysis and for manufacturing of nanoparticle-based products. Here we demonstrate a disposable microfluidic particle sorter that enables high-throughput, on-demand counting and binary sorting of sub-micron particles and cells, using either fluorescence or an electrically-based determination of particle size. Size-based sorting uses a resistive pulse sensor integrated on-chip, while fluorescence-based discrimination is achieved using on-the-fly optical image capture and analysis. Following detection and analysis, the individual particles are deflected using a pair of piezoelectric actuators, directing the particles into one of two desired output channels; the main flow goes into a third waste channel. The integrated system can achieve sorting fidelities of better than 98\\%, and the mechanism can successfully count and actuate, on demand, more than 60,000 particles/min.

Sukumar Rajauria; Christopher Axline; Claudia Gottstein; Andrew N. Cleland

2014-12-05T23:59:59.000Z

474

Integration of alternative feedstreams for biomass treatment and utilization  

DOE Patents (OSTI)

The present invention provides a method for treating biomass composed of integrated feedstocks to produce fermentable sugars. One aspect of the methods described herein includes a pretreatment step wherein biomass is integrated with an alternative feedstream and the resulting integrated feedstock, at relatively high concentrations, is treated with a low concentration of ammonia relative to the dry weight of biomass. In another aspect, a high solids concentration of pretreated biomass is integrated with an alternative feedstream for saccharifiaction.

Hennessey, Susan Marie (Avondale, PA); Friend, Julie (Claymont, DE); Dunson, Jr., James B. (Newark, DE); Tucker, III, Melvin P. (Lakewood, CO); Elander, Richard T. (Evergreen, CO); Hames, Bonnie (Westminster, CO)

2011-03-22T23:59:59.000Z

475

Buried waste integrated demonstration technology integration process  

SciTech Connect

A Technology integration Process was developed for the Idaho National Energy Laboratories (INEL) Buried Waste Integrated Demonstration (BWID) Program to facilitate the transfer of technology and knowledge from industry, universities, and other Federal agencies into the BWID; to successfully transfer demonstrated technology and knowledge from the BWID to industry, universities, and other Federal agencies; and to share demonstrated technologies and knowledge between Integrated Demonstrations and other Department of Energy (DOE) spread throughout the DOE Complex. This document also details specific methods and tools for integrating and transferring technologies into or out of the BWID program. The document provides background on the BWID program and technology development needs, demonstrates the direction of technology transfer, illustrates current processes for this transfer, and lists points of contact for prospective participants in the BWID technology transfer efforts. The Technology Integration Process was prepared to ensure compliance with the requirements of DOE`s Office of Technology Development (OTD).

Ferguson, J.S.; Ferguson, J.E.

1992-04-01T23:59:59.000Z

476

Buried waste integrated demonstration technology integration process  

SciTech Connect

A Technology integration Process was developed for the Idaho National Energy Laboratories (INEL) Buried Waste Integrated Demonstration (BWID) Program to facilitate the transfer of technology and knowledge from industry, universities, and other Federal agencies into the BWID; to successfully transfer demonstrated technology and knowledge from the BWID to industry, universities, and other Federal agencies; and to share demonstrated technologies and knowledge between Integrated Demonstrations and other Department of Energy (DOE) spread throughout the DOE Complex. This document also details specific methods and tools for integrating and transferring technologies into or out of the BWID program. The document provides background on the BWID program and technology development needs, demonstrates the direction of technology transfer, illustrates current processes for this transfer, and lists points of contact for prospective participants in the BWID technology transfer efforts. The Technology Integration Process was prepared to ensure compliance with the requirements of DOE's Office of Technology Development (OTD).

Ferguson, J.S.; Ferguson, J.E.

1992-04-01T23:59:59.000Z

477

Area-and Throughput-Optimized VLSI Architecture of Sphere Decoding  

E-Print Network (OSTI)

, Andreas Burg Integrated Systems Laboratory ETH Zurich, CH-8092 Zurich, Switzerland E-mail: {mawenk,bruderer,apburg}@iis.ee.ethz.ch Christoph Studer Communication Technology Laboratory ETH Zurich, CH-8092 Zurich, Switzerland E-mail: studerc

478

Integrated genomic characterization of endometrial carcinoma  

E-Print Network (OSTI)

We performed an integrated genomic, transcriptomic and proteomic characterization of 373 endometrial carcinomas using array- and sequencing-based technologies. Uterine serous tumours and ~25% of high-grade endometrioid ...

Lander, Eric S.

479

Spatial Mapping of Protein Abundances in the Mouse Brain by Voxelation...  

NLE Websites -- All DOE Office Websites (Extended Search)

Mapping of Protein Abundances in the Mouse Brain by Voxelation Integrated with High-Throughput Liquid Chromatography Spatial Mapping of Protein Abundances in the Mouse Brain by...

480

PHYSICAL REVIEW B 90, 174107 (2014) High-throughput computational screening of thermal conductivity, Debye temperature, and  

E-Print Network (OSTI)

for the past few decades [6]. Low thermal conductivity materials constitute the basis of a new generation such as the Debye temperature and the thermal conductivity of materials. We demonstrate that the AGL method, which ranking of the thermal conductivity for several different classes of semiconductor materials

Curtarolo, Stefano

Note: This page contains sample records for the topic "integrated high throughput" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


481

Exploration, Registration, and Analysis of High-Throughput 3D Microscopy Data from the Knife-Edge Scanning Microscope  

E-Print Network (OSTI)

connectivity analysis; (2) the size of the uncompressed KESM data exceeds a few terabytes and to compare and combine with other data sets from different imaging modalities, the KESM data must be registered to a standard coordinate space; and (3) quantitative...

Sung, Chul

2014-04-25T23:59:59.000Z

482

Development of High-Throughput and Real-Time Methods for the Detection of Infectious Enteric Viruses  

E-Print Network (OSTI)

Mattoussi, H. , J. M. Mauro, E. R. Goldman, G. P. Anderson,Twigg, H. Mattoussi, J. M. Mauro, J. R. Deschamps. 2004. AI. L. Medintz, J. M. Mauro, B. R. Fisher, M. G. Bawendi, and

YEH, HSIAO-YUN

2010-01-01T23:59:59.000Z

483

Inhibitors of Leishmania GDP-Mannose Pyrophosphorylase Identified by High-Throughput Screening of Small-Molecule Chemical Library  

Science Journals Connector (OSTI)

...copy of the compound library and retested in triplicate...is a critical global public health priority. Leishmania...small-molecule chemical library of 80,000 drug-like...design of the chemical library being that lead-like...better cover diversity space. We have commented in...

Kurt Lackovic; John P. Parisot; Nerida Sleebs; Jonathan B. Baell; Laurent Debien; Keith G. Watson; Joan M. Curtis; Emanuela Handman; Ian P. Street; Lukasz Kedzierski

2010-02-16T23:59:59.000Z

484

High-Throughput Ultra-Performance LCMS-MS Method for Analysis of Diclofenac Sodium in Rabbit Plasma  

Science Journals Connector (OSTI)

......glacial acetic) and water (pH 3.5), in a ratio...analysis was done by using a Waters Acquity H-Class UPLC-tandem...TQD was equipped with atmospheric pressure electrospray...accessories were nitrogen generator (Peak Scientific, Scotland...glacial acetic acid) and water (pH 3.5, adjusted......

Mohd Aftab Alam; Fahad I. Al-Jenoobi; Abdullah M. Al-Mohizea

2014-03-01T23:59:59.000Z

485

Anonymous nuclear loci in non-model organisms: making the most of high-throughput genome surveys  

Science Journals Connector (OSTI)

......de novo and anonymous nuclear loci (ANL) are proving...produce robust multilocus datasets. Results: By successively...129-142. Anonymous nuclear loci in non-model...de novo and anonymous nuclear loci (ANL) are proving...produce robust multilocus datasets. RESULTS: By successively......

Terry Bertozzi; Kate L. Sanders; Mark J. Sistrom; Michael G. Gardner

2012-07-15T23:59:59.000Z

486

Supplementary Information to Ovaskainen et al. (2013): Combining high-throughput sequencing with fruit body surveys reveals contrasting life-  

E-Print Network (OSTI)

sequencing with fruit body surveys reveals contrasting life- history strategies in fungi the decay class in which the species typically appeared as mycelia (or as fruit by and the prevalence of the species in decay classes as fruit bodies ( ) and mycelia

Bruns, Tom

487

The Development of Microfabricated Microbial Fuel Cell Array as a High Throughput Screening Platform for Electrochemically Active Microbes  

E-Print Network (OSTI)

: Illustration of the 24-well air-cathode MFC array. (1) Anode layer, (2) anode chamber layer, (3) air-cathode layer (PEM/carbon cloth assembly), (4) air-cathode interface. B: Air-cathode interface microfabrication steps. (1) Au/Ti deposited PMMA substrate...

Hou, Huijie

2012-02-14T23:59:59.000Z

488

Ambient-atmosphere glow discharge for determination of elemental concentration in solutions in a high-throughput or transient fashion  

DOE Patents (OSTI)

An ambient atmosphere glow discharge spectrometer is disclosed having a capillary, two electrodes and a means for recording the atomic emissions.

Webb, Michael R. (Somerville, MA); Hieftje, Gary M. (Bloomington, IN); Andrade, Francisco (Leeds, GB)

2011-04-19T23:59:59.000Z

489

A cell based high-throughput screening approach for the discovery of new inhibitors of respiratory syncytial virus  

E-Print Network (OSTI)

was assessed using Cell Titer Glo.factors greater than 0.8 (0.82 0.02), however, the CV Figure 3 Dose response of ribavirin. HEp-2 cells were plated in 384-well black tissue culture plates at 2,000 cells per well. Ribavirin or carrier control (DMSO) were... The positive control drug for this assay, ribavirin (MP Biomedicals, Solon, OH) was solubilized in DMSO, diluted and added to the assay plates as described for Chung et al. Virology Journal 2013, 10:19 Page 10 of 12 http://www.virologyj.com/content/10/1/19test...

Chung, Dong-Hoon; Moore, Blake P.; Matharu, Daljit S.; Golden, Jennifer E.; Maddox, Clinton; Rasmussen, Lynn; Sosa, Melinda I.; Ananthan, Subramaniam; White, E. Lucile; Jia, Fuli; Jonsson, Colleen B.; Severson, William E.

2013-01-10T23:59:59.000Z

490

Development of High-Throughput Screens to Target SAM-I Riboswitches (2014 DOE JGI Genomics of Energy & Environment Meeting)  

SciTech Connect

Scott Hickey of the University of California Berkeley speaks at the 9th Annual Genomics of Energy & Environment Meeting on March 20, 2014 in Walnut Creek, Calif.

Hickey, Scott [UC Berkely

2014-03-19T23:59:59.000Z

491

Implementation of a High-Throughput Screen for Identifying Small Molecules to Activate the Keap1-Nrf2-ARE Pathway  

E-Print Network (OSTI)

Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor that induces a battery of cytoprotective genes involved in antioxidant defense through binding to Antioxidant Response Elements (ARE) located in the promoter regions...

Wu, Kai Connie; McDonald, Peter R.; Liu, Jie Jerry; Chaguturu, Rathnam; Klaassen, Curtis D.

2012-10-08T23:59:59.000Z

492

Manufacturing improvement and thermal property characterization of the frame structure of an Ultra-high Throughput Mutational Spectrometer  

E-Print Network (OSTI)

Constant denaturant capillary electrophoresis (CDCE) is a DNA separation technique that allows the detection of mutants at a fraction of 10???. CDCE uses a region of constant temperature and constant denaturant concentration ...

Lin, Jiengju J. (Jiengju James)

2005-01-01T23:59:59.000Z

493

Development of High-throughput and Robust Microfluidic Live Cell Assay Platforms for Combination Drug and Toxin Screening  

E-Print Network (OSTI)

was a circular chamber with cell-trapping sieves. This 576-chamber microfluidic array was used to screen three cell types (BALB/3T3, HeLa, and bovine endothelial cells) against a panel of five toxins (digitonin, saponin, CoCl2, NiCl2, acrolein...

Wang, Han

2012-02-14T23:59:59.000Z

494

A Micro-aspirator Chip Using Vacuum Expanded Microchannels for High-throughput Mechanical Characterization of Biological Cells  

E-Print Network (OSTI)

of the cantilever. The magnitude of the deflection is captured by a laser beam. The laser beam reflects off Stage Piezoelectric Scanner LaserMirror Tip Sample Photodiode Detector 13 the cantilever, the angular direction of which changes as the tip... undergoes deflections. The reflected beams are captured and converted into electrical signals by a position- sensitive photodetector (photodiode). By calculating the difference in signal of the photodiode, the amount of deflection can be correlated...

Kim, Woosik

2011-10-21T23:59:59.000Z

495

Dissecting the Phenotypic Components of Crop Plant Growth and Drought Responses Based on High-Throughput Image Analysis  

Science Journals Connector (OSTI)

...Genetics and Crop Plant Research (IPK), D-06466 Gatersleben, Germany b Department of Bioinformatics, College of Life Sciences, Zhejiang University, Hangzhou 310058, P.R. China www.plantcell.org/cgi/doi/10.1105/tpc.114.129601...

Dijun Chen; Kerstin Neumann; Swetlana Friedel; Benjamin Kilian; Ming Chen; Thomas Altmann; Christian Klukas

2014-12-11T23:59:59.000Z

496

JOURNAL OF LIGHTWAVE TECHNOLOGY, VOL. 13, NO. 6, JUNE 1995 1085 A Three-Dimensional High-Throughput  

E-Print Network (OSTI)

in the performance and reliability of the optoelectronic devices and the slowing down of the electrical interconnect depends on the accuracy of the models used for representing the behavior of the optoelectronic devices, optoelectronic devices are usually modeled as simple RC networks [8-10]. These models fail to capture some

Wills, Scott

497

Fabrication of high-throughput critical-angle X-ray transmission gratings for wavelength-dispersive spectroscopy  

E-Print Network (OSTI)

The development of the critical-angle transmission (CAT) grating seeks both an order of magnitude improvement in the effective area, and a factor of three increase in the resolving power of future space-based, soft x-ray ...

Bruccoleri, Alexander Robert

2013-01-01T23:59:59.000Z

498

A Cell-Based High-Throughput Screen for Novel Chemical Inducers of Fetal Hemoglobin for Treatment of Hemoglobinopathies  

E-Print Network (OSTI)

treatment for sickle cell disease (SCD) is increased fetal hemoglobin (HbF). Identification of a drug specific for inducing c-globin expression in pediatric and adult patients, with minimal off-target effects, continues to be an elusive goal. One hurdle has..., Kansas, United States of America c Current address: SRI International, Harrisonburg, Virginia, United States of America Introduction Sickle cell disease (SCD) is the most common monogenetic disease diagnosed in the United States, affecting approximately...

Peterson, Kenneth R.; Costa, Flá via C.; Fedosyuk, Halyna; Neades, Renee Y.; Chazelle, Allen M.; Zelenchuk, Lesya; Fonteles, Andrea H.; Dalal, Parmita; Roy, Anuradha; Chaguturu, Rathnam; Li, Biaoru; Pace, Betty S.

2014-09-16T23:59:59.000Z

499

High-Throughput Screening of Mg-Functionalized Metal-Organic Frameworks for Hydrogen Storage near Room Temperature  

E-Print Network (OSTI)

The hydrogen storage capabilities of 18,383 porous crystalline structures possessing various degrees of Mg functionalization and diverse physical properties were assessed through combined grand canonical Monte Carlo (GCMC) and quantum mechanical...

Coln, Yamil J.; Fairen-Jimenez, David; Wilmer, Christopher E.; Snurr, Randall Q.

2014-01-01T23:59:59.000Z

500

Nanograined half-Heusler semiconductors as advanced thermoelectrics: an ab-initio high-throughput statistical study  

E-Print Network (OSTI)

@duke.edu Abstract Nanostructuring has spurred a revival in the field of direct thermoelectric energy conversion. This leads to increased conversion efficiencies. Despite considerable effort in opti- mizing the known materials re- mains elusive due to several challenging factors.1,2 Effective thermoelectrics must have

Curtarolo, Stefano