Sample records for induced adaptive response

  1. Regular PaperJ. Radiat. Res., 51, 657664 (2010) Adaptive Response in Zebrafish Embryos Induced Using

    E-Print Network [OSTI]

    Yu, K.N.

    2010-01-01T23:59:59.000Z

    in the zebrafish embryos in vivo. INTRODUCTION For radiation protection purposes, prediction of risk from this model is commonly adopted for radiation protection purposes, there is a considerable amount of evidenceRegular PaperJ. Radiat. Res., 51, 657­664 (2010) Adaptive Response in Zebrafish Embryos Induced

  2. Flavin-Induced Oligomerization in Escherichia coli Adaptive Response Protein AidB

    E-Print Network [OSTI]

    Drennan, Catherine L.

    The process known as “adaptive response” allows Escherichia coli to respond to small doses of DNA-methylating agents by upregulating the expression of four proteins. While the role of three of these proteins in mitigating ...

  3. Flavin-Induced Oligomerization in Escherichia coli Adaptive Response Protein AidB

    SciTech Connect (OSTI)

    Hamill, Michael J.; Jost, Marco; Wong, Cintyu; Elliott, Sean J.; Drennan, Catherine L. (MIT); (BU)

    2011-11-21T23:59:59.000Z

    The process known as 'adaptive response' allows Escherichia coli to respond to small doses of DNA-methylating agents by upregulating the expression of four proteins. While the role of three of these proteins in mitigating DNA damage is well understood, the function of AidB is less clear. Although AidB is a flavoprotein, no catalytic role has been established for the bound cofactor. Here we investigate the possibility that flavin plays a structural role in the assembly of the AidB tetramer. We report the generation and biophysical characterization of deflavinated AidB and of an AidB mutant that has greatly reduced affinity for flavin adenine dinucleotide (FAD). Using fluorescence quenching and analytical ultracentrifugation, we find that apo AidB has a high affinity for FAD, as indicated by an apparent dissociation constant of 402.1 {+-} 35.1 nM, and that binding of substoichiometric amounts of FAD triggers a transition in the AidB oligomeric state. In particular, deflavinated AidB is dimeric, whereas the addition of FAD yields a tetramer. We further investigate the dimerization and tetramerization interfaces of AidB by determining a 2.8 {angstrom} resolution crystal structure in space group P3{sub 2} that contains three intact tetramers in the asymmetric unit. Taken together, our findings provide strong evidence that FAD plays a structural role in the formation of tetrameric AidB.

  4. Radiation-induced bystander effect and adaptive response in mammalian cells

    E-Print Network [OSTI]

    with cells whose nuclei have been traversed with a single alpha particle each. Pretreatment of cells-induced cancer has traditionally been estimated from cancer incidence among Japanese A-bomb survivors. These data in the absence of definitive data. Both the interna- tional commission on radiation protection (ICRP

  5. adaptive survival responses: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    changing environment using sleep. We also quantified 15 Scaling adaptation: climate change response and Geosciences Websites Summary: , and the barriers to adaptation are...

  6. Stress Response & Adaptation: A New Molecular Toolkit

    E-Print Network [OSTI]

    Storey, Kenneth B.

    · Covalent attachment of: Antibodies, Oligonucleotides · Capture of proteins, peptides, coding and non pathways that are responsible for responding to &/or repairing cellular damage. E.g. antioxidant enzymes

  7. Global transcriptional, physiological and metabolite analyses of Desulfovibrio vulgaris Hildenborough responses to salt adaptation

    SciTech Connect (OSTI)

    He, Z.; Zhou, A.; Baidoo, E.; He, Q.; Joachimiak, M. P.; Benke, P.; Phan, R.; Mukhopadhyay, A.; Hemme, C.L.; Huang, K.; Alm, E.J.; Fields, M.W.; Wall, J.; Stahl, D.; Hazen, T.C.; Keasling, J.D.; Arkin, A.P.; Zhou, J.

    2009-12-01T23:59:59.000Z

    The response of Desulfovibrio vulgaris Hildenborough to salt adaptation (long-term NaCl exposure) was examined by physiological, global transcriptional, and metabolite analyses. The growth of D. vulgaris was inhibited by high levels of NaCl, and the growth inhibition could be relieved by the addition of exogenous amino acids (e.g., glutamate, alanine, tryptophan) or yeast extract. Salt adaptation induced the expression of genes involved in amino acid biosynthesis and transport, electron transfer, hydrogen oxidation, and general stress responses (e.g., heat shock proteins, phage shock proteins, and oxidative stress response proteins). Genes involved in carbon metabolism, cell motility, and phage structures were repressed. Comparison of transcriptomic profiles of D. vulgaris responses to salt adaptation with those of salt shock (short-term NaCl exposure) showed some similarity as well as a significant difference. Metabolite assays showed that glutamate and alanine were accumulated under salt adaptation, suggesting that they may be used as osmoprotectants in D. vulgaris. A conceptual model is proposed to link the observed results to currently available knowledge for further understanding the mechanisms of D. vulgaris adaptation to elevated NaCl.

  8. The versatile E. coli adaptive response protein AlkB mitigates toxicity and mutagenicity of etheno-, ethano-, and methyl-modified bases in vivo

    E-Print Network [OSTI]

    Frick, Lauren Elizabeth

    2007-01-01T23:59:59.000Z

    The Escherichia coli AlkB protein is an exceptionally versatile DNA repair enzyme. Its expression is induced upon exposure to alkylating agents as part of the Ada-mediated adaptive response. This member of the ac-ketoglu ...

  9. Radiation-induced gene responses

    SciTech Connect (OSTI)

    Woloschak, G.E.; Paunesku, T.; Shearin-Jones, P.; Oryhon, J.

    1996-12-31T23:59:59.000Z

    In the process of identifying genes that are differentially regulated in cells exposed to ultraviolet radiation (UV), we identified a transcript that was repressed following the exposure of cells to a combination of UV and salicylate, a known inhibitor of NF-kappaB. Sequencing this band determined that it has identify to lactate dehydrogenase, and Northern blots confirmed the initial expression pattern. Analysis of the sequence of the LDH 5` region established the presence of NF-kappaB, Sp1, and two Ap-2 elements; two partial AP- 1; one partial RE, and two halves of E-UV elements were also found. Electromobility shift assays were then performed for the AP-1, NF- kappaB, and E-UV elements. These experiments revealed that binding to NF-kappaB was induced by UV but repressed with salicylic acid; UV did not affect AP-1 binding, but salicylic acid inhibited it alone or following UV exposure; and E-UV binding was repressed by UV, and salicylic acid had little effect. Since the binding of no single element correlated with the expression pattern of LDH, it is likely that multiple elements govern UV/salicylate-mediated expression.

  10. Distributed Demand Response and User Adaptation in Smart Grids

    E-Print Network [OSTI]

    Fan, Zhong

    2010-01-01T23:59:59.000Z

    This paper proposes a distributed framework for demand response and user adaptation in smart grid networks. In particular, we borrow the concept of congestion pricing in Internet traffic control and show that pricing information is very useful to regulate user demand and hence balance network load. User preference is modeled as a willingness to pay parameter which can be seen as an indicator of differential quality of service. Both analysis and simulation results are presented to demonstrate the dynamics and convergence behavior of the algorithm.

  11. adaptive responses genomic: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    3 Biochemical Adaptation 169 From: Integrative Physiology in the Proteomics and Post-Genomics Age Biology and Medicine Websites Summary: Biochemical Adaptation 169 169 From:...

  12. Triptolide, an Inhibitor of the Human Heat Shock Response That Enhances Stress-induced Cell Death*S

    E-Print Network [OSTI]

    Morimoto, Richard

    Triptolide, an Inhibitor of the Human Heat Shock Response That Enhances Stress-induced Cell Death chaperones, inducible by heat shock and a variety of other stresses, have critical roles in protein homeostasis, balancing cell stress with adaptation, survival, and cell death mechanisms. In transformed cells

  13. Soil erosion from sugar beet in Central Europe in response to climate change induced seasonal precipitation variations

    E-Print Network [OSTI]

    Quinton, John

    of adaptive land-use management for climate change response strategies in the agricultural sector. © 2007; Conservation agriculture; Erosion modelling 1. Introduction Climate change of anthropogenic origin is widelySoil erosion from sugar beet in Central Europe in response to climate change induced seasonal

  14. Seismic response of fractures and induced anisotropy in poroelastic media

    E-Print Network [OSTI]

    Santos, Juan

    Seismic response of fractures and induced anisotropy in poroelastic media Juan E. Santos stituto) and R. Mart´inez Corredor (UNLP) Department of Mathematics, University of Calgary, October 2014 Seismic variations of velocity and attenuation of seismic waves. Seismic response of fractures and induced anisotropy

  15. Adaptive Evolution of a Stress Response Protein Tom J. Little1

    E-Print Network [OSTI]

    Obbard, Darren

    Stress responses classically involve heat shock proteins or molecular chaperones that maintain proteinAdaptive Evolution of a Stress Response Protein Tom J. Little1 *, Lenny Nelson2 , Ted Hupp2 1 of the mammalian stress response gene SEP53, a member of the epidermal differentiation complex fused-gene family

  16. In vivo imaging of C. elegans ASH neurons: cellular response and adaptation to chemical repellents

    E-Print Network [OSTI]

    Schafer, William R.

    Erratum In vivo imaging of C. elegans ASH neurons: cellular response and adaptation to chemical neurons highlighted. From the ASH cell body, the dendrite runs anteriorly until the tip of the head ending

  17. adaptive response induced: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NANOLAMINATES . Open Access Theses and Dissertations Summary: ??To characterize the self-propagating, high-temperature exothermic alloying reactions of NiAl nanoscaled...

  18. adaptive responses induced: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NANOLAMINATES . Open Access Theses and Dissertations Summary: ??To characterize the self-propagating, high-temperature exothermic alloying reactions of NiAl nanoscaled...

  19. adaptive immune response: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    vivo imaging of immune cell dynamics in skin in response to zinc-oxide nanoparticle exposure Boppart, Stephen 205 Transcriptomic Analysis of Host Immune and Cell Death...

  20. adaptive immune responses: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    vivo imaging of immune cell dynamics in skin in response to zinc-oxide nanoparticle exposure Boppart, Stephen 205 Transcriptomic Analysis of Host Immune and Cell Death...

  1. Adaptive phenotypic differentiation of courtship in response to recent anthropogenic disturbance

    E-Print Network [OSTI]

    Candolin, Ulrika

    differentiated in response to spatial variation in human-induced eutrophication? Populations: Parallel pairs-induced eutrophication during the last decades. Methods: Males from mildly and severely eutrophied habitats were allowed variation in human-induced eutrophication. The differentiation should improve individual fitness. Keywords

  2. Between adaptation and resistance : labor responses to globalization in France

    E-Print Network [OSTI]

    Ancelovici, Marcos, 1971-

    2008-01-01T23:59:59.000Z

    This dissertation aims at accounting for labor responses to globalization in France. It addresses this issue through a comparative study of two labor organizations-the French Democratic Labor Confederation (CFDT) and the ...

  3. the Adaptive Response, Genetic Haplo-Insufficiency and Genomic Instability

    SciTech Connect (OSTI)

    Geard, Charles R.

    2014-12-12T23:59:59.000Z

    The linear no-threshold (LNT) hypothesis is the driving force in the establishment of radiation protection standards. However, the scientific basis for linearity has been brought into question, particularly due to the concerns about induced radiation resistance as it pertains to oxidative stress. Specifically, we investigated the observation that tumor hypoxia is associated with malignant progression, increased metastases, chemo- and radioresistance and poor prognosis. Experiments were conducted with non-malignant 3T3/NIH cells and normal human lung fibroblasts (NHLF) that were subjected to ?-irradiation under the levels of oxygen resembling those in growing tumors, and related our data to the concentrations of dissolved oxygen (DO), which is a better indicator of the amounts of residual oxygen inside the cells cultured in the hypoxic or anoxic atmosphere. We found that at DO levels about 0.5 mg/L cells subjected to both short-term (17 hours) and prolonged (48-72 hours) hypoxia continued to proliferate, and that apoptotic events were decreased at the early hours of hypoxic treatment. We showed that the short-term hypoxia up-regulated p53-binding protein 1 (53BP1) and resulted in facilitated 53BP1 nuclear foci formation and disappearance, thus indicating the higher efficiency of DNA double strand breaks repair processes. The latter was confirmed by the lower micronuclei incidence in irradiated hypoxic cells.

  4. Alcohol-induced suppression of the humoral immune response

    SciTech Connect (OSTI)

    Stolen, J.S.; Draxler, S.; Nagle, J.J.

    1985-01-01T23:59:59.000Z

    The authors report here that summer flounder (Paralichthys dentatus) pretreated by injection of a small amount of the common alcohol, ethanol, or ethanol containing PCB, showed complete suppression of the immune response to a formalin-killed sewage sludge isolate of the human enteric bacteria, E. coli. The unresponsiveness persisted for up to 42 days after injection of bacteria. Demonstrable agglutinating antibody to E. coli was seen in unpretreated fish after seven days. A second injection of bacteria 42 days after the first in pretreated fish, now resulted in immune responsiveness although the magnitude of the response resembled a primary response, indicating that memory to the first injection was also suppressed. Slightly lower responses were seen in the groups of fish injected with ethanol containing the PCB Aroclor 1254 when compared with those given ethanol alone, but the major suppression was alcohol-induced.

  5. THE RESPONSE OF GALL-INDUCING SCALE INSECTS (HEMIPTERA: ERIOCOCCIDAE: APIOMORPHA

    E-Print Network [OSTI]

    Cranston, Peter S.

    THE RESPONSE OF GALL-INDUCING SCALE INSECTS (HEMIPTERA: ERIOCOCCIDAE: APIOMORPHA RÜBSAAMEN-inducing scale insects (Hemiptera: Eriococcidae: Apiomorpha Rübsaamen) to the fire history of mallee eucalypts

  6. Hydrogen-peroxide-induced oxidative stress responses in Desulfovibrio vulgaris Hildenborough

    E-Print Network [OSTI]

    Zhou, A.

    2010-01-01T23:59:59.000Z

    Escherichia coli response to hydrogen peroxide. J Bacteriolagainst superoxide and hydrogen peroxide. Annu Rev BiochemHydrogen peroxide-induced oxidative stress responses in

  7. Role for mTOR Signaling and Neuronal Activity in Morphine-Induced Adaptations in Ventral Tegmental Area Dopamine Neurons

    E-Print Network [OSTI]

    Mazei-Robison, Michelle S.

    While the abuse of opiate drugs continues to rise, the neuroadaptations that occur with long-term drug exposure remain poorly understood. We describe here a series of chronic morphine-induced adaptations in ventral tegmental ...

  8. Why occupancy-responsive adaptive thermostats do not always save -and the limits for when they should

    E-Print Network [OSTI]

    California at Davis, University of

    Why occupancy-responsive adaptive thermostats do not always save - and the limits for when thermostats do not guarantee energy savings. As a result, EPA ended EnergyStar certification of programmable, and adaptive control schemes have shown significant annual HVAC savings on the order of 10-20%. However

  9. Scientists in a Changed Institutional Environment: Subjective Adaptation and Social Responsibility Norms in Russia

    SciTech Connect (OSTI)

    Gerber, T P; Ball, D Y

    2008-06-05T23:59:59.000Z

    How do scientists react when the institutional setting in which they conduct their work changes radically? How do long-standing norms regarding the social responsibility of scientists fare? What factors influence whether scientists embrace or reject the new institutions and norms? We examine these questions using data from a unique survey of 602 scientists in Russia, whose science system experienced a sustained crisis and sweeping changes in science institutions following the collapse of the Soviet Union. We develop measures of how respondents view financing based on grants and other institutional changes in the Russian science system, as well as measures of two norms regarding scientists social responsibility. We find that the majority of scientists have adapted, in the sense that they hold positive views of the new institutions, but a diversity of orientations remains. Social responsibility norms are common among Russian scientists, but far from universal. The main correlates of adaptation are age and current success at negotiating the new institutions, though prospective success, work context, and ethnicity have some of the hypothesized associations. As for social responsibility norms, the main source of variation is age: younger scientists are more likely to embrace individualistic rather than socially-oriented norms.

  10. Influence of Insulin Resistance on Contractile Activity-Induced Anabolic Response of Skeletal Muscle 

    E-Print Network [OSTI]

    Nilsson, Mats I.

    2011-02-22T23:59:59.000Z

    Although the long-term therapeutic benefits of exercise are indisputable, contractile activity may induce divergent adaptations in insulin-resistant vs. insulin-sensitive skeletal muscle. The purpose of this study was to ...

  11. Cyclic 3',5'-AMP Relay i n Dictyostelium discoideum V. Adaptation of the CAMP Signaling Response

    E-Print Network [OSTI]

    Devreotes, Peter

    Cyclic 3',5'-AMP Relay i n Dictyostelium discoideum V. Adaptation of the CAMP Signaling Response, and then immediately given test stimuli of 10-8 M to 2.5 X 10-7 M cAMP. The response to a given test stimulus to the concentration of the test stimulus . The responses to test stimuli of 10-8, 5 X 10-8, 10-7, or 2.5 X 10-7 M c

  12. LDRD final report on adaptive-responsive nanostructures for sensing applications.

    SciTech Connect (OSTI)

    Shelnutt, John Allen; van Swol, Frank B.; Wang, Zhongchun; Medforth, Craig J.

    2005-11-01T23:59:59.000Z

    Functional organic nanostructures such as well-formed tubes or fibers that can easily be fabricated into electronic and photonic devices are needed in many applications. Especially desirable from a national security standpoint are nanostructures that have enhanced sensitivity for the detection of chemicals and biological (CB) agents and other environmental stimuli. We recently discovered the first class of highly responsive and adaptive porphyrin-based nanostructures that may satisfy these requirements. These novel porphyrin nanostructures, which are formed by ionic self-assembly of two oppositely charged porphyrins, may function as conductors, semiconductors, or photoconductors, and they have additional properties that make them suitable for device fabrication (e.g., as ultrasensitive colorimetric CB microsensors). Preliminary studies with porphyrin nanotubes have shown that these nanostructures have novel optical and electronic properties, including strong resonant light scattering, quenched fluorescence, and electrical conductivity. In addition, they are photochemically active and capable of light-harvesting and photosynthesis; they may also have nonlinear optical properties. Remarkably, the nanotubes and potentially other porphyrin nanostructure are mechanically responsive and adaptive (e.g., the rigidity of the micrometers-long nanotubes is altered by light, ultrasound, or chemicals) and they self-heal upon removal the environmental stimulus. Given the tremendous degree of structural variation possible in the porphyrin subunits, additional types of nanostructures and greater control over their morphology can be anticipated. Molecular modification also provides a means of controlling their electronic, photonic, and other functional properties. In this work, we have greatly broadened the range of ionic porphyrin nanostructures that can be made, and determined the optical and responsivity properties of the nanotubes and other porphyrin nanostructures. We have also explored means for controlling their morphology, size, and placement on surfaces. The research proposed will lay the groundwork for the use of these remarkable porphyrin nanostructures in micro- and nanoscale devices, by providing a more detailed understanding of their molecular structure and the factors that control their structural, photophysical, and chemical properties.

  13. Histological and anatomical responses in avocado, Persea americana, induced by the vascular wilt

    E-Print Network [OSTI]

    Blanchette, Robert A.

    Histological and anatomical responses in avocado, Persea americana, induced by the vascular wilt: Raffaelea lauricola causes laurel wilt of avocado, Persea americana. Host × pathogen interactions were examined with light and scanning electron microscopy. The susceptible avocado cultivar `Simmonds

  14. Fuel-Induced System Responses The Role Unconventional Fuels May...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    in Attaining Low Temperature Diesel Combustion System-Response Issues Imposed by Biodiesel in a Medium-Duty Diesel Engine New Diesel Emissions Control Strategy for U.S. Tier 2...

  15. Magnetic response enhancement via electrically induced magnetic moments

    E-Print Network [OSTI]

    B. Jungnitsch; J. Evers

    2008-04-22T23:59:59.000Z

    The realization of negative refraction in atomic gases requires a strong magnetic response of the atoms. Current proposals for such systems achieve an enhancement of the magnetic response by a suitable laser field configuration, but still rely on high gas densities. Thus further progress is desirable, and this requires an understanding of the precise mechanism for the enhancement. Therefore, here we study the magnetic and electric response to a probe field interacting with three-level atoms in ladder configuration. In our first model, the three transitions are driven by a control field and the electric and magnetic component of the probe field, giving rise to a closed interaction loop. In a reference model, the coherent driving is replaced by an incoherent pump field. A time-dependent analysis of the closed-loop system enables us to identify the different contributions to the medium response. A comparison with the reference system then allows one to identify the physical mechanism that leads to the enhancement. It is found that the enhancement occurs at so-called multiphoton resonance by a scattering of the coupling field and the electric probe field mode into the magnetic probe field mode. Based on these results, conditions for the enhancement are discussed.

  16. Investigations of ultrafast nuclear response induced by resonant and nonresonant laser pulses

    E-Print Network [OSTI]

    Kumar, Anand T.N.

    Investigations of ultrafast nuclear response induced by resonant and nonresonant laser pulses Anand by ultrashort laser pulses interacting with a two electronic level molecular system. Fully quantum mechanical to implement. The behavior of the first two moments with respect to various parameters such as the pulse

  17. Morphological responses and sediment processes following a typhoon-induced dam failure, Dahan

    E-Print Network [OSTI]

    Tullos, Desiree

    Morphological responses and sediment processes following a typhoon-induced dam failure, Dahan River gravel and sand was exposed when Barlin Dam failed during Typhoon WeiPa in 2007. The dam was located configuration, and distance from the dam is needed to explain the rate and pattern of morphological changes

  18. Response to ``Comment on `Ultrasound-induced lung hemorrhage is not caused by inertial cavitation'''

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    Response to ``Comment on `Ultrasound-induced lung hemorrhage is not caused by inertial cavitation cavitation nuclei in lung versus other tissues such that overpressure does not affect the inertial cavitation threshold in lung, then there would be an impact on the con- clusion in our publication.2 To examine

  19. Arsenic- and cadmium-induced toxicogenomic response in mouse embryos undergoing neurulation

    SciTech Connect (OSTI)

    Robinson, Joshua F.; Yu, Xiaozhong [Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA 98195 (United States); Institute for Risk Analysis and Risk Communication, Seattle, WA 98195 (United States); Moreira, Estefania G. [Institute for Risk Analysis and Risk Communication, Seattle, WA 98195 (United States); Department of Physiological Sciences, State University of Londrina, Londrina, PR (Brazil); Hong, Sungwoo [Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA 98195 (United States); Institute for Risk Analysis and Risk Communication, Seattle, WA 98195 (United States); Faustman, Elaine M., E-mail: faustman@u.washington.edu [Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA 98195 (United States); Institute for Risk Analysis and Risk Communication, Seattle, WA 98195 (United States); Center for Ecogenetics and Environmental Health, Seattle, WA 98195 (United States); Center on Human Development and Disability, Seattle, WA 98195 (United States); Center for Child Environmental Health Risks Research, Seattle, WA 98195 (United States)

    2011-01-15T23:59:59.000Z

    Arsenic (As) and cadmium (Cd) are well-characterized teratogens in animal models inducing embryotoxicity and neural tube defects (NTDs) when exposed during neurulation. Toxicological research is needed to resolve the specific biological processes and associated molecular pathways underlying metal-induced toxicity during this timeframe in gestational development. In this study, we investigated the dose-dependent effects of As and Cd on gene expression in C57BL/6J mouse embryos exposed in utero during neurulation (GD8) to identify significantly altered genes and corresponding biological processes associated with embryotoxicity. We quantitatively examined the toxicogenomic dose-response relationship at the gene level. Our results suggest that As and Cd induce dose-dependent gene expression alterations representing shared (cell cycle, response to UV, glutathione metabolism, RNA processing) and unique (alcohol/sugar metabolism) biological processes, which serve as robust indicators of metal-induced developmental toxicity and indicate underlying embryotoxic effects. Our observations also correlate well with previously identified impacts of As and Cd on specific genes associated with metal-induced toxicity (Cdkn1a, Mt1). In summary, we have identified in a quantitative manner As and Cd induced dose-dependent effects on gene expression in mouse embryos during a peak window of sensitivity to embryotoxicity and NTDs in the sensitive C57BL/6J strain.

  20. Risk Analysis and Adaptive Response Planning for Water Distribution Systems Contamination Emergency Management

    E-Print Network [OSTI]

    Rasekh, Amin

    2012-10-19T23:59:59.000Z

    are investigated. Pressure-driven hydraulic analysis is performed to simulate the complicated system hydraulics under pressure-deficit conditions. Performance of a novel preventive response action ? injection of food-grade dye directly into drinking water...

  1. Field-resolved measurement of reaction-induced spectral densities by polarizability response spectroscopy

    SciTech Connect (OSTI)

    Moran, Andrew M.; Nome, Rene A.; Scherer, Norbert F. [Department of Chemistry and the James Franck Institute, University of Chicago, 929 East 57th St., Chicago, Illinois 60637 (United States)

    2007-11-14T23:59:59.000Z

    The experimental design and theoretical description of a novel five-pulse laser spectroscopy is presented with an application to a pyridinium charge transfer complex in acetonitrile and methanol. In field-resolved polarizability response spectroscopy (PORS), an electronically resonant laser pulse first excites a solvated chromophore (reactant) and off-resonant Raman spectra of the resulting nuclear motions are measured as a function of the reaction time. The present apparatus differs from our earlier design by performing the Raman probe measurement (with fixed pulse delays) in the frequency domain. In addition, the full electric fields of the signals are measured by spectral interferometry to separate nonresonant and Raman responses. Our theoretical model shows how the PORS signal arises from nuclear motions that are displaced/driven by the photoinduced reaction. The field-resolved off-resonant (of the solute's electronic transitions) probing favors detection of solvent (as opposed to solute) dynamics coupled to the reaction. The sign of the signal represents the relative strengths of polarization responses associated with the ground and photoexcited solutions. Signatures of nonresonant and PORS signal contributions to the experimental results are analyzed with numerical calculations based on a theoretical model we have developed for reaction-induced PORS. Our model identifies two mechanisms of PORS signal generation: (i) structural relaxation induced resonance; (ii) dephasing induced resonance. In the charge transfer reaction investigated, the solvent-dependent and time-evolving (solvent) polarizability spectral density (PSD) is readily obtained. The general trend of an initial broadband inertial nuclear response followed by a decrease in the linewidth of the PSD establishes that the measured PSD is inconsistent with the approximation of a linear response. Furthermore, the explicit time evolution of the PSD is important for properly describing solvent control of reactions that do not satisfy the time-scale separability inherent to nonadiabatic kinetic models.

  2. Ultrafast terahertz-induced response of GeSbTe phase-change materials

    SciTech Connect (OSTI)

    Shu, Michael J. [Department of Applied Physics, Stanford University, Stanford, California 94305 (United States); Stanford Institute for Materials and Energy Sciences, SLAC National Accelerator Laboratory, Menlo Park, California 94025 (United States); Zalden, Peter [Stanford Institute for Materials and Energy Sciences, SLAC National Accelerator Laboratory, Menlo Park, California 94025 (United States); PULSE Institute, SLAC National Accelerator Laboratory, Menlo Park, California 94025 (United States); Chen, Frank [Stanford Institute for Materials and Energy Sciences, SLAC National Accelerator Laboratory, Menlo Park, California 94025 (United States); Department of Electrical Engineering, Stanford University, Stanford, California 94305 (United States); Weems, Ben [Department of Materials Science and Engineering, Stanford University, Stanford, California 94305 (United States); Chatzakis, Ioannis [Stanford Institute for Materials and Energy Sciences, SLAC National Accelerator Laboratory, Menlo Park, California 94025 (United States); Xiong, Feng; Jeyasingh, Rakesh; Pop, Eric; Philip Wong, H.-S. [Department of Electrical Engineering, Stanford University, Stanford, California 94305 (United States); Hoffmann, Matthias C. [SLAC National Accelerator Laboratory, Menlo Park, California 94025 (United States); Wuttig, Matthias [I. Physikalisches Institut, RWTH Aachen University, 52056 Aachen (Germany); JARA–Fundamentals of Information Technology, RWTH Aachen University, 52056 Aachen (Germany); Lindenberg, Aaron M., E-mail: aaronl@stanford.edu [Stanford Institute for Materials and Energy Sciences, SLAC National Accelerator Laboratory, Menlo Park, California 94025 (United States); PULSE Institute, SLAC National Accelerator Laboratory, Menlo Park, California 94025 (United States); Department of Materials Science and Engineering, Stanford University, Stanford, California 94305 (United States)

    2014-06-23T23:59:59.000Z

    The time-resolved ultrafast electric field-driven response of crystalline and amorphous GeSbTe films has been measured all-optically, pumping with single-cycle terahertz pulses as a means of biasing phase-change materials on a sub-picosecond time-scale. Utilizing the near-band-gap transmission as a probe of the electronic and structural response below the switching threshold, we observe a field-induced heating of the carrier system and resolve the picosecond-time-scale energy relaxation processes and their dependence on the sample annealing condition in the crystalline phase. In the amorphous phase, an instantaneous electroabsorption response is observed, quadratic in the terahertz field, followed by field-driven lattice heating, with Ohmic behavior up to 200?kV/cm.

  3. Removal of N-Alkyl Modifications from N[superscript 2]-Alkylguanine and N[superscript 4]-Alkylcytosine in DNA by the Adaptive Response Protein AlkB

    E-Print Network [OSTI]

    Li, Deyu

    The AlkB enzyme is an Fe(II)- and ?-ketoglutarate-dependent dioxygenase that repairs DNA alkyl lesions by a direct reversal of damage mechanism as part of the adaptive response in E. coli. The reported substrate scope of ...

  4. Neurodegeneration and adaptation in response to low-dose photon irradiation

    SciTech Connect (OSTI)

    Limoli, Charles L. [UCI

    2014-10-27T23:59:59.000Z

    Neural stem and precursor cells (i.e. multipotent neural cells) are concentrated in the neurogenic regions of the brain (hippocampal dentate gyrus, subventricular zones), and considerable evidence suggests that these cells are important in mediating the stress response of the CNS after damage from ionizing radiation. The capability of these cells to proliferate, migrate and differentiate (i.e. to undergo neurogenesis) suggests they can participate in the repair and maintenance of CNS functions by replacing brain cells damaged or depleted due to irradiation. Importantly, we have shown that multipotent neural cells are markedly sensitive to irradiation and oxidative stress, insults that compromise neurogenesis and hasten the onset and progression of degenerative processes that are likely to have an adverse impact on cognition. Our past and current work has demonstrated that relatively low doses of radiation cause a persistent (weeks-months) oxidative stress in multipotent neural cells that can elicit a range of degenerative sequelae in the CNS. Therefore, our project is focused on determining the extent that endogenous and redox sensitive multipotent neural cells represent important radioresponsive targets for low dose radiation effects. We hypothesize that the activation of redox sensitive signaling can trigger radioadaptive changes in these cells that can be either harmful or beneficial to overall cognitive health.

  5. Continuum resonance induced electromagnetic torque by a rotating plasma response to static resonant magnetic perturbation field

    SciTech Connect (OSTI)

    Liu Yueqiang; Connor, J. W.; Cowley, S. C.; Ham, C. J.; Hastie, R. J.; Hender, T. C. [Euratom/CCFE Fusion Association, Culham Science Centre, Abingdon OX14 3DB (United Kingdom)

    2012-10-15T23:59:59.000Z

    A numerical study is carried out, based on a simple toroidal tokamak equilibrium, to demonstrate the radial re-distribution of the electromagnetic torque density, as a result of a rotating resistive plasma (linear) response to a static resonant magnetic perturbation field. The computed electromagnetic torque peaks at several radial locations even in the presence of a single rational surface, due to resonances between the rotating response, in the plasma frame, and both Alfven and sound continuum waves. These peaks tend to merge together to form a rather global torque distribution, when the plasma resistivity is large. The continuum resonance induced net electromagnetic torque remains finite even in the limit of an ideal plasma.

  6. Adaptation and adaptability : expectant design for resilience in coastal urbanity

    E-Print Network [OSTI]

    Ruskeepää, Laura A. Delaney (Laura Ashley Delaney)

    2011-01-01T23:59:59.000Z

    What is the nature of and possibility for urban resiliency through adaptation? Adaptation implies responsiveness to phenomena that are disruptive to a system's functioning; it is a willful evolution in response to changed ...

  7. Adaptive Survey Design Andrew Sage

    E-Print Network [OSTI]

    Carriquiry, Alicia

    . Andrew Sage Iowa State University CSSM March 14, 2014 2 / 35 #12;Adaptive and Responsive Designs collection, although they may be revised during data collection. A responsive design is an adaptive design

  8. REGULATORY MECHANISMS OF SLC39A4 (ZIP4) AND SLC39A5 (ZIP5) IN THE ADAPTIVE RESPONSE TO ZINC AVAILABILITY

    E-Print Network [OSTI]

    Weaver, Benjamin Patrick

    2009-04-06T23:59:59.000Z

    REGULATORY MECHANISMS OF SLC39A4 (ZIP4) AND SLC39A5 (ZIP5) IN THE ADAPTIVE RESPONSE TO ZINC AVAILABILITY by Copyright 2009 Benjamin Patrick Weaver B.S., Biochemistry, Wichita State University, Wichita, KS, 2001 M.S., Biological Sciences... of esoteric conversations, and for your friendship. Thank you for putting up with me and for always listening. The friendship of some other previous lab members: Yong Li for your friendship and suffering my mispronounced Chinese. Taiho Kambe...

  9. Regulation Of Nf=kb And Mnsod In Low Dose Radiation Induced Adaptive Protection Of Mouse And Human Skin Cells

    SciTech Connect (OSTI)

    Jian Li

    2012-11-07T23:59:59.000Z

    A sampling of publications resulting from this grant is provided. One is on the subject of NF-κB-Mediated HER2 Overexpression in Radiation-Adaptive Resistance. Another is on NF-κB-mediated adaptive resistance to ionizing radiation.

  10. Enniatin B-induced cell death and inflammatory responses in RAW 267.4 murine macrophages

    SciTech Connect (OSTI)

    Gammelsrud, A. [Norwegian Veterinary Institute, P.O. Box 750, Centrum, N-0106 Oslo (Norway) [Norwegian Veterinary Institute, P.O. Box 750, Centrum, N-0106 Oslo (Norway); Department of Air Pollution and Noise, Division of Environmental Medicine, Norwegian Institute of Public Health, N-0403 Oslo (Norway); Solhaug, A. [Norwegian Veterinary Institute, P.O. Box 750, Centrum, N-0106 Oslo (Norway)] [Norwegian Veterinary Institute, P.O. Box 750, Centrum, N-0106 Oslo (Norway); Dendelé, B. [EA 4427 SeRAIC, IRSET, Université de Rennes 1, IFR 140, Rennes (France)] [EA 4427 SeRAIC, IRSET, Université de Rennes 1, IFR 140, Rennes (France); Sandberg, W.J. [Department of Air Pollution and Noise, Division of Environmental Medicine, Norwegian Institute of Public Health, N-0403 Oslo (Norway)] [Department of Air Pollution and Noise, Division of Environmental Medicine, Norwegian Institute of Public Health, N-0403 Oslo (Norway); Ivanova, L. [Norwegian Veterinary Institute, P.O. Box 750, Centrum, N-0106 Oslo (Norway)] [Norwegian Veterinary Institute, P.O. Box 750, Centrum, N-0106 Oslo (Norway); Kocbach Bølling, A. [Department of Air Pollution and Noise, Division of Environmental Medicine, Norwegian Institute of Public Health, N-0403 Oslo (Norway)] [Department of Air Pollution and Noise, Division of Environmental Medicine, Norwegian Institute of Public Health, N-0403 Oslo (Norway); Lagadic-Gossmann, D. [EA 4427 SeRAIC, IRSET, Université de Rennes 1, IFR 140, Rennes (France)] [EA 4427 SeRAIC, IRSET, Université de Rennes 1, IFR 140, Rennes (France); Refsnes, M.; Becher, R. [Department of Air Pollution and Noise, Division of Environmental Medicine, Norwegian Institute of Public Health, N-0403 Oslo (Norway)] [Department of Air Pollution and Noise, Division of Environmental Medicine, Norwegian Institute of Public Health, N-0403 Oslo (Norway); Eriksen, G. [Norwegian Veterinary Institute, P.O. Box 750, Centrum, N-0106 Oslo (Norway)] [Norwegian Veterinary Institute, P.O. Box 750, Centrum, N-0106 Oslo (Norway); Holme, J.A., E-mail: jorn.holme@fhi.no [Department of Air Pollution and Noise, Division of Environmental Medicine, Norwegian Institute of Public Health, N-0403 Oslo (Norway)

    2012-05-15T23:59:59.000Z

    The mycotoxin enniatin B (EnnB) is predominantly produced by species of the Fusarium genera, and often found in grain. The cytotoxic effect of EnnB has been suggested to be related to its ability to form ionophores in cell membranes. The present study examines the effects of EnnB on cell death, differentiation, proliferation and pro-inflammatory responses in the murine monocyte–macrophage cell line RAW 264.7. Exposure to EnnB for 24 h caused an accumulation of cells in the G0/G1-phase with a corresponding decrease in cyclin D1. This cell cycle-arrest was possibly also linked to the reduced cellular ability to capture and internalize receptors as illustrated by the lipid marker ganglioside GM1. EnnB also increased the number of apoptotic, early apoptotic and necrotic cells, as well as cells with elongated spindle-like morphology. The Neutral Red assay indicated that EnnB induced lysosomal damage; supported by transmission electron microscopy (TEM) showing accumulation of lipids inside the lysosomes forming lamellar structures/myelin bodies. Enhanced levels of activated caspase-1 were observed after EnnB exposure and the caspase-1 specific inhibitor ZYVAD-FMK reduced EnnB-induced apoptosis. Moreover, EnnB increased the release of interleukin-1beta (IL-1?) in cells primed with lipopolysaccharide (LPS), and this response was reduced by both ZYVAD-FMK and the cathepsin B inhibitor CA-074Me. In conclusion, EnnB was found to induce cell cycle arrest, cell death and inflammation. Caspase-1 appeared to be involved in the apoptosis and release of IL-1? and possibly activation of the inflammasome through lysosomal damage and leakage of cathepsin B. -- Highlights: ? The mycotoxin EnnB induced cell cycle arrest, cell death and inflammation. ? The G0/G1-arrest was linked to a reduced ability to internalize receptors. ? EnnB caused lysosomal damage, leakage of cathepsin B and caspase-1 cleavage. ? Caspase-1 was partly involved in both apoptosis and release of IL-1?. ? There was a synergistic action between EnnB and bacterial LPS.

  11. A Role for Repressive Histone Methylation in Cocaine-Induced Vulnerability to Stress

    E-Print Network [OSTI]

    Covington, Herbert E.

    Substance abuse increases an individual's vulnerability to stress-related illnesses, which is presumably mediated by drug-induced neural adaptations that alter subsequent responses to stress. Here, we identify repressive ...

  12. Geomechanical response of permafrost-associated hydrate deposits to depressurization-induced gas production

    SciTech Connect (OSTI)

    Rutqvist, J.; Moridis, G.J.; Grover, T.; Collett, T.

    2009-02-01T23:59:59.000Z

    In this simulation study, we analyzed the geomechanical response during depressurization production from two known hydrate-bearing permafrost deposits: the Mallik (Northwest Territories, Canada) deposit and Mount Elbert (Alaska, USA) deposit. Gas was produced from these deposits at constant pressure using horizontal wells placed at the top of a hydrate layer (HL), located at a depth of about 900 m at the Mallik and 600 m at the Mount Elbert. The simulation results show that general thermodynamic and geomechanical responses are similar for the two sites, but with substantially higher production and more intensive geomechanical responses at the deeper Mallik deposit. The depressurization-induced dissociation begins at the well bore and then spreads laterally, mainly along the top of the HL. The depressurization results in an increased shear stress within the body of the receding hydrate and causes a vertical compaction of the reservoir. However, its effects are partially mitigated by the relatively stiff permafrost overburden, and compaction of the HL is limited to less than 0.4%. The increased shear stress may lead to shear failure in the hydrate-free zone bounded by the HL overburden and the downward-receding upper dissociation interface. This zone undergoes complete hydrate dissociation, and the cohesive strength of the sediment is low. We determined that the likelihood of shear failure depends on the initial stress state as well as on the geomechanical properties of the reservoir. The Poisson's ratio of the hydrate-bearing formation is a particularly important parameter that determines whether the evolution of the reservoir stresses will increase or decrease the likelihood of shear failure.

  13. Climate response to tropical cyclone-induced ocean mixing in an1 Earth system model of intermediate complexity2

    E-Print Network [OSTI]

    Climate response to tropical cyclone-induced ocean mixing in an1 Earth system model of intermediate system model of intermediate complexity. The parameterization is based on21 previously published global. Abstract19 We introduce a parameterization of ocean mixing by tropical cyclones (TCs) into20 an Earth

  14. Carbon fullerenes (C60s) can induce inflammatory responses in the lung of mice

    SciTech Connect (OSTI)

    Park, Eun-Jung [College of Pharmacy, Dongduk Women's University, 23-1, Wolgok-dong, Seongbuk-gu, Seoul 136-714 (Korea, Republic of); Kim, Hero; Kim, Younghun [Department of Chemical Engineering, Kwangwoon University, 447-1, Wolgye-dong, Nowon-gu, Seoul 139-701 (Korea, Republic of); Yi, Jongheop [School of Chemical and Biological Engineering, Seoul National University, 599 Gwanangno, Gwanak-gu, Seoul 151-742 (Korea, Republic of); Choi, Kyunghee [Department of Chemical Assessment, National Institute of Environmental Research, Kyungseo-dong, Seo-gu, Incheon 404-708 (Korea, Republic of); Park, Kwangsik, E-mail: kspark@dongduk.ac.k [College of Pharmacy, Dongduk Women's University, 23-1, Wolgok-dong, Seongbuk-gu, Seoul 136-714 (Korea, Republic of)

    2010-04-15T23:59:59.000Z

    Fullerenes (C60s) occur in the environment due to natural and anthropogenic sources such as volcanic eruptions, forest fires, and the combustion of carbon-based materials. Recently, production and application of engineered C60s have also rapidly increased in diverse industrial fields and biomedicine due to C60' unique physico-chemical properties, so toxicity assessment on environmental and human health is being evaluated as a valuable work. However, data related to the toxicity of C60s have not been abundant up to now. In this study, we studied the immunotoxic mechanism and change of gene expression caused by the instillation of C60s. As a result, C60s induced an increase in sub G1 and G1 arrest in BAL cells, an increase in pro-inflammatory cytokines such as IL-1, TNF-alpha, and IL-6, and an increase of Th1 cytokines such as IL-12 and IFN-r in BAL fluid. In addition, IgE reached the maximum at 1 day after treatment in both BAL fluid and the blood, and decreased in a time-dependent manner. Gene expression of the MHC class II (H2-Eb1) molecule was stronger than that of the MHC class I (H2-T23), and an increase in T cell distribution was also observed during the experiment period. Furthermore, cell infiltration and expression of tissue damage related genes in lung tissue were constantly observed during the experiment period. Based on this, C60s may induce inflammatory responses in the lung of mice.

  15. amp-induced hyperglycaemic response: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Load Management Programs CATEE Conference October, 2012 Agenda Outline I. General Demand Response Definition II. General Demand Response Program Rules III. CenterPoint...

  16. ON AN ADAPTIVE CONTROL ALGORITHM FOR ADAPTIVE OPTICS APPLICATIONS

    E-Print Network [OSTI]

    ON AN ADAPTIVE CONTROL ALGORITHM FOR ADAPTIVE OPTICS APPLICATIONS MOODY T. CHU Abstract. The wavefront aberrations induced by atmospheric turbulence can severely degrade the performance of an optical imaging system. Adaptive optics refers to the process of removing unwanted wave front distortions

  17. ON AN ADAPTIVE CONTROL ALGORITHM FOR ADAPTIVE OPTICS APPLICATIONS

    E-Print Network [OSTI]

    ON AN ADAPTIVE CONTROL ALGORITHM FOR ADAPTIVE OPTICS APPLICATIONS MOODY T. CHU \\Lambda Abstract. The wavefront aberrations induced by atmospheric turbulence can severely degrade the performance of an optical imaging system. Adaptive optics refers to the process of removing unwanted wave front distortions

  18. Optical near-field induced visible response photoelectrochemical water splitting on nanorod TiO{sub 2}

    SciTech Connect (OSTI)

    Thu Hac Huong Le; Mawatari, Kazuma; Pihosh, Yuriy; Kitamori, Takehiko [Department of Applied Chemistry, Graduate School of Engineering, University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-8656 (Japan); Kawazoe, Tadashi; Yatsui, Takashi; Ohtsu, Motoichi [Department of Electrical Engineering and Information Systems, Graduate School of Engineering, University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-8656 (Japan); Tosa, Masahiro [Micro-Nano Component Materials Group, Materials Engineering Laboratory, National Institute for Materials Science (NIMS), Sengen 1-2-1, Tsukuba, Ibaraki 305-0047 (Japan)

    2011-11-21T23:59:59.000Z

    Here we report a way to induce the visible response of non-doped TiO{sub 2} in the photocatalytic electrochemical water splitting, which is achieved by utilizing the optical near-field (ONF) generated on nanorod TiO{sub 2}. The visible response is attributed to the ONF-induced phonon-assisted excitation process, in which TiO{sub 2} is excited by sub-bandgap photons via phonon energy. Our approach directly gets involved in the excitation process without chemical modification of materials; accordingly it is expected to have few drawbacks on the photocatalytic performance. This study may offer another perspective on the development of solar harvesting materials.

  19. adaptive interactive technologies: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Shock-induced combustion Fluid-structure interaction Implementation Parallel Adaptive Cartesian Upwind Mathematics Websites Summary: Finite volume methods Adaptive mesh refinement...

  20. Interactions of foot-and-mouth disease virus with cells in organised lymphoid tissue influence innate and adaptive immune responses 

    E-Print Network [OSTI]

    Juleff, Nicholas Dylan

    2009-01-01T23:59:59.000Z

    to that in the controls, including rapid isotype switching to IgG antibody. These data suggest that antibody responses to sites on the surface of the virus capsid are T cell-independent whereas those directed against the non-structural proteins are T cell-dependent. CD4...

  1. On the characteristics of fault-induced rotor-dynamic bifurcations and nonlinear responses

    E-Print Network [OSTI]

    Yang, Baozhong

    2004-11-15T23:59:59.000Z

    and Poincare map of the response in (a) .........41 3.4 (a) Time history of a nonlinear time-delay model. (b) Corresponding phase portrait and Poincare map of the response in (a) .........42 3.5 Phase portrait and Poincare map of a fractal... reaction forces, which in turn could result in strong nonlinear responses including period-doubling bifurcation, quasi-periodic bifurcation, and even chaotic response [4,5]. Nonlinear dynamical states of quasi-periodic, fractal, and chaotic motions...

  2. Dynamic Response of a Rotor-air Bearing System Due to Base Induced Periodic Motions

    E-Print Network [OSTI]

    Niu, Yaying

    2010-01-14T23:59:59.000Z

    equipment such as turbochargers and micro gas turbine engines. For example, air flow fluctuations and landing sudden maneuver can introduce random excitations or shock to auxiliary power units for aircrafts. Diesel engine induced vibrations and road...

  3. Adapting the U.S. Domestic Radiological Emergency Response Process to an Overseas Incident: FRMAC Without the F

    SciTech Connect (OSTI)

    Blumenthal, Daniel J. [USDOE NA Office of Emergency Response; Bowman, David R. [USDOE NA Office of Emergency Response; Remick, Alan [USDOE NA Office of Emergency Response

    2012-05-01T23:59:59.000Z

    The earthquake and resulting tsunami in Japan led to a radiological release from the Fukushima Daiichi Nuclear Power Plan, which in turn resulted in the rapid activation and deployment by the U.S. Department of Energy National Nuclear Security Administration (DOE/NNSA) emergency response teams. These teams and those from other federal agencies are typically coordinated through the Federal Radiological Monitoring and Assessment Center (FRMAC) when responding to radiological incidents in the U.S. FRMAC is the body through which the collection, analysis, and assessment of environmental radiological data are coordinated and products released to decision makers. This article discusses DOE/NNSA’s role in the U.S. response to the Fukushima accident as it implemented its components of FRMAC in a foreign country, coordinated its assets, integrated with its federal partners, and collaborated with the Government of Japan. The technical details of the various data collections and analyses are covered in other articles of this issue.

  4. Role of estrogen receptor alpha (ER alpha) insulin-like growth factor (IGF)-I-induced responses in MCF-7 breast cancer cells

    E-Print Network [OSTI]

    Zhang, Shu

    2009-05-15T23:59:59.000Z

    ROLE OF ESTROGEN RECEPTOR ? (ER?) IN INSULIN-LIKE GROWTH FACTOR (IGF)-I-INDUCED RESPONSES IN MCF-7 BREAST CANCER CELLS A Dissertation by SHU ZHANG Submitted to the Office of Graduate Studies of Texas A&M University in partial... fulfillment of the requirements for the degree of DOCTOR OF PHILOSOPHY December 2007 Major Subject: Toxicology ROLE OF ESTROGEN RECEPTOR ? (ER?) IN INSULIN-LIKE GROWTH FACTOR (IGF)-I-INDUCED RESPONSES IN MCF-7 BREAST CANCER CELLS A Dissertation...

  5. Role of estrogen receptor alpha (ER alpha) insulin-like growth factor (IGF)-I-induced responses in MCF-7 breast cancer cells 

    E-Print Network [OSTI]

    Zhang, Shu

    2009-05-15T23:59:59.000Z

    Insulin-like growth factor-I (IGF-I) is a mitogenic polypeptide that induces proliferation and activation of kinase pathways in MCF-7 breast cancer cells. The role of estrogen receptor ? (ER?) in mediating responses induced by IGF-I was investigated...

  6. Influence of soil permeability on liquefaction-induced lateral pile response

    E-Print Network [OSTI]

    Ramirez, Jose Manuel

    2010-01-01T23:59:59.000Z

    and Goh, S. H. (2003). "Pile response to lateral spreads:Goh, S. H. (2003). "Single piles in lateral spreads: FieldSpreading and its Effects on Pile Foundations, Ph.D. Thesis,

  7. Response

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn'tOrigin ofEnergy at Waste-to-Energy usingof Enhanced Dr. JuliaPOINTRespond to theResponse SEAB

  8. A tale of two houses: the human dimension of demand response enabling technology from a case study of an adaptive wireless thermostat.

    E-Print Network [OSTI]

    Peffer, Therese; Arens, Edward A; Chen, Xue; Jang, Jaehwi; Auslander, David M.

    2008-01-01T23:59:59.000Z

    and Ed Arens. 2008. Demand Response-Enabled ResidentialEfficiency and Demand Response Programs for 2005/2006.The Human Dimension of Demand Response Enabling Technology

  9. Cortisol-induced inhibition of ovine renin and aldosterone responses to hypotension

    SciTech Connect (OSTI)

    Wood, C.E.; Silbiger, J.

    1987-03-01T23:59:59.000Z

    Previous studies from this laboratory have demonstrated that in preterm fetal sheep increases in plasma cortisol (F) concentration equal in amplitude to fetal F stress responses suppress plasma renin activity (PRA). The purpose of this study was to investigate the possibility that this negative interaction exists in adult sheep. Cortisol was measured by radioimmunoassay. Five conscious ewes with chronically prepared carotid arterial loops were infused intravenously with F or vehicle for 5 h. One hour after the end of F or vehicle infusion, renin secretion was stimulated by hypotension produced by infusion of sodium nitroprusside. F infusion increased plasma F; during vehicle infusion plasma F did not change. F infusion decreased hematocrit from 29 +/- 2 to 26 +/- 1%. Basal PRA in vehicle- and F-infused groups were 0.4 +/- 0 and 0.2 +/- 0.1 ng angiotensin I-ml/sup -1/-h/sup -1/ and did not change. In vehicle-infused ewes, PRA increased from 0.4 +/- 0 to 4.6 +/- 0.4 and plasma aldosterone from 26.0 +/- 1.0 to 173.1 +/- 21.8 pg/ml, while in F-infused ewes, PRA increased from 0.2 +/- 1 to 3.3 +/- 0.4 ng angiotensin I-ml/sup -1/-h/sup -1/ and aldosterone from 25.0 +/- 0 to 48.2 +/- 23.2 pg/ml, significantly smaller responses. These results suggest that repeated stress may modulate the responses of the renin-angiotensin system in this species.

  10. Physiological response specificity to induced stress as predicted by perceptual and expectancy style

    E-Print Network [OSTI]

    Williams, Rodney Don

    1978-01-01T23:59:59.000Z

    , as proposed by Lacey, (1976). It is suggested that it may be possible to predict differential response specificity on the basis of perceptual and and expectancy style. CHAPTER II METHOD ~Saa atta The subjects were 44 undergraduate students at a large.... 114 0. 045 1. 045 1. 746 1. 863 1. 886 2. 113" 3. 000 1. 000 1. 341 1. 818 1. 841 2. 068' 2, 999' 0. 341 0. 818 0. 841 1. 068 1. 999' 0. 477 0. 500 0. 727 1, 614 0. 023 0. 250 1. 137 0. 727 1. 114 0. 887 22 TABLE 8 SUMMARY OF NEWMAN KEULS...

  11. System-based identification of toxicity pathways associated with multi-walled carbon nanotube-induced pathological responses

    SciTech Connect (OSTI)

    Snyder-Talkington, Brandi N. [Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505 (United States); Dymacek, Julian [Lane Department of Computer Science and Electrical Engineering, West Virginia University, Morgantown, WV 26506-6070 (United States); Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, WV 26506-9300 (United States); Porter, Dale W.; Wolfarth, Michael G.; Mercer, Robert R. [Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505 (United States); Pacurari, Maricica [Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, WV 26506-9300 (United States); Denvir, James [Department of Biochemistry and Microbiology, Marshall University, Huntington, WV 25755 (United States); Castranova, Vincent [Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505 (United States); Qian, Yong, E-mail: yaq2@cdc.gov [Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505 (United States); Guo, Nancy L., E-mail: lguo@hsc.wvu.edu [Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, WV 26506-9300 (United States)

    2013-10-15T23:59:59.000Z

    The fibrous shape and biopersistence of multi-walled carbon nanotubes (MWCNT) have raised concern over their potential toxicity after pulmonary exposure. As in vivo exposure to MWCNT produced a transient inflammatory and progressive fibrotic response, this study sought to identify significant biological processes associated with lung inflammation and fibrosis pathology data, based upon whole genome mRNA expression, bronchoaveolar lavage scores, and morphometric analysis from C57BL/6J mice exposed by pharyngeal aspiration to 0, 10, 20, 40, or 80 ?g MWCNT at 1, 7, 28, or 56 days post-exposure. Using a novel computational model employing non-negative matrix factorization and Monte Carlo Markov Chain simulation, significant biological processes with expression similar to MWCNT-induced lung inflammation and fibrosis pathology data in mice were identified. A subset of genes in these processes was determined to be functionally related to either fibrosis or inflammation by Ingenuity Pathway Analysis and was used to determine potential significant signaling cascades. Two genes determined to be functionally related to inflammation and fibrosis, vascular endothelial growth factor A (vegfa) and C-C motif chemokine 2 (ccl2), were confirmed by in vitro studies of mRNA and protein expression in small airway epithelial cells exposed to MWCNT as concordant with in vivo expression. This study identified that the novel computational model was sufficient to determine biological processes strongly associated with the pathology of lung inflammation and fibrosis and could identify potential toxicity signaling pathways and mechanisms of MWCNT exposure which could be used for future animal studies to support human risk assessment and intervention efforts. - Highlights: • A novel computational model identified toxicity pathways matching in vivo pathology. • Systematic identification of MWCNT-induced biological processes in mouse lungs • MWCNT-induced functional networks of lung inflammation and fibrosis were revealed. • Two functional, representative genes, ccl2 and vegfa, were validated in vitro.

  12. Rotational response of superconductors: magneto-rotational isomorphism and rotation-induced vortex lattice

    E-Print Network [OSTI]

    Egor Babaev; Boris Svistunov

    2014-03-03T23:59:59.000Z

    The analysis of nonclassical rotational response of superfluids and superconductors was performed by Onsager (in 1949) \\cite{Onsager} and London (in 1950) \\cite{London} and crucially advanced by Feynman (in 1955) \\cite{Feynman}. It was established that, in thermodynamic limit, neutral superfluids rotate by forming---without any threshold---a vortex lattice. In contrast, the rotation of superconductors at angular frequency ${\\bf \\Omega}$---supported by uniform magnetic field ${\\bf B}_L\\propto {\\bf \\Omega}$ due to surface currents---is of the rigid-body type (London Law). Here we show that, neglecting the centrifugal effects, the behavior of a rotating superconductor is identical to that of a superconductor placed in a uniform fictitious external magnetic filed $\\tilde{\\bf H}=- {\\bf B}_L$. In particular, the isomorphism immediately implies the existence of two critical rotational frequencies in type-2 superconductors.

  13. Chemomechanical oscillations in a responsive gel induced by an autocatalytic reaction

    SciTech Connect (OSTI)

    Li, Kai [Department of Civil Engineering, Anhui Jianzhu University, Hefei, Anhui 230601 (China); Wu, Peiyi [State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai 200433 (China); Cai, Shengqiang, E-mail: shqcai@ucsd.edu [State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai 200433 (China); Department of Mechanical and Aerospace Engineering, University of California, San Diego, La Jolla, California 92093 (United States)

    2014-07-28T23:59:59.000Z

    In this article, we investigate dynamic behaviors of a gel layer attached to a rigid substrate and submerged in a continuous stirred tank reactor. With a continuous feed of fresh reactants in the reactor, the concentrations of reactants stay constant on the surface of the gel layer. However, the concentrations of reactants inside the gel are inhomogeneous and vary with time, which are determined by the diffusion and chemical reactions of the reactants. Additionally, both monotonic and oscillatory swelling-shrinking dynamics are predicted in the gel if the swelling capability of the gel depends on the concentration of a reactant. Based on autocatalytic reaction, kinetic model, and nonequilibrium thermodynamic theory of gels, in this article, we investigate the effect of the thickness of the gel layer, lateral prestretches in the gel and the initial concentrations of reactants in the gel on its dynamic behaviors. We have also calculated the evolution of the swelling force that the gel layer exerts on its constrained substrate. The results of this article may find potential applications in using responsive gels to make chemo-mechanical sensors, actuators, biomimetic devices, and even drug delivery systems.

  14. Type 2 Innate Immunity in Helminth Infection Is Induced Redundantly and Acts Autonomously following CD11c Cell

    E-Print Network [OSTI]

    Maizels, Rick

    in stimulating Th2 adaptive immunity against these helminths through depletion of CD11chigh cells of basophils by antibody treatment. Th2 responses can be induced by adoptive transfer of DCs, but not basophils, exposed to soluble excretory-secretory products from these helminths. However, innate type 2 responses

  15. Spectral Response of the Pulsationally-Induced Shocks in the Atmosphere of BW Vulpeculae

    E-Print Network [OSTI]

    Myron A. Smith; C. Simon Jeffery

    2002-10-08T23:59:59.000Z

    The star BW Vul excites an extremely strong radial pulsation that grows in its envelope and is responsible for visible shock features in the continuum flux and spectral line profiles emerging in the atmosphere At two phases separated by 0.8 cycles. Material propelled upwards in the atmosphere from the shock returns to the lower photosphere where it creates a second shock just before the start of the next cycle. We have obtained three nights of echelle data for this star over about 5 pulsation cycles (P = 0.201 days) in order to evaluate the effects of on a number of important lines in the spectrum, including the HeI 5875A and 6678A lines. These data were supplemented by archival high-dispersion IUE (UV) data from 1994. A comparison of profiles of the two HeI lines during the peak of the infall activity suggests that differences in the development of the blue wing at this time are due to heating and short-lived formations of an optically thin layer above the atmospheric region compressed by the infall. This discovery and the well-known decreases in equivalent widths of the CII 6578-83A doublet at the two shock phases, suggests that shock flattens the temperature gradient and produces heating in heating the upper atmosphere. Except for absorptions in the blue wings of the UV resonance lines, we find no evidence for sequential shock delays arriving at various regions of line formation of the photosphere (a "Van Hoof effect"). Phase lags cited by some former observers may be false indicators arising from varying degrees of desaturation of multiple lines, such as for the red HeI lines. In addition, an apparent lag in the equivalent width curve of lines arising from less excited atomic levels could instead be caused by post-shock cooling, followed by a rebound shock.

  16. Ultrafast terahertz-induced response of GeSbTe phase-change materials Michael J. Shu,1,2,a)

    E-Print Network [OSTI]

    Ultrafast terahertz-induced response of GeSbTe phase-change materials Michael J. Shu,1,2,a) Peter-optically, pumping with single-cycle terahertz pulses as a means of biasing phase-change materials on a sub of these materials is important for predicting the field-driven heating and phase-change behavior. However

  17. COMMENTARY:Limits to adaptation

    SciTech Connect (OSTI)

    Preston, Benjamin L [ORNL

    2013-01-01T23:59:59.000Z

    An actor-centered, risk-based approach to defining limits to social adaptation provides a useful analytic framing for identifying and anticipating these limits and informing debates over society s responses to climate change.

  18. Structural response in FeCl2 (iron chloride) to pressure-induced electro-magnetic transitions

    SciTech Connect (OSTI)

    Taylor, R D [Los Alamos National Laboratory; Rozenberg, G Kh [TEL AVIV UNIV; Pasternak, M P [TEL AVIV UNIV; Gorodetsky, P [TEL AVIV UNIV; Xu, W M [TEL AVIV UNIV; Dubrovinsky, L S [UNIV OF BAYREUTH; Le Bihan, T L [FRANCE

    2009-01-01T23:59:59.000Z

    High pressure (HP) synchrotron x-ray diffraction studies were carried out in FeCl{sub 2} together with resistivity (R) studies, at various temperatures and pressures to 65 GPa using diamond anvil cells. This work follows a previous HP {sup 57}Fe Mossbauer study in which two pressure-induced (PI) electronic transitions were found interpreted as: (i) quenching of the orbital-term contribution to the hyperfine field concurring with a tilting of the magnetic moment by 55 degrees and (ii) collapse of the magnetism concurring with a sharp decrease of the isomer shift (IS). The R(P,T) studies affirm that the cause the collapse of the magnetism is a PI p-d correlation breakdown, leading to an insulator-metal transition at {approx}45 GPa and is not due to a spi-Ir,crossover (S=2 {yields} S=0). The structure response to the pressure evolution of the two electronic phase transitions starting at low pressures (LP), through an intermediate phase (IP) 30-57 GPa, and culminating in a high-pressure phase (HP), P >32 GPa, can clearly be quantified. The IP-HP phases coexist through the 32-57 GPa range in which the HP abundance increases monotonically at the expense of the IP phase. At the LP-IP interface no volume change is detected, yet the c-axis increases and the a-axis shrinks by 0.21 Angstroms and 0.13 Angstroms, respectively. The fit of the equation of state of the combined LP-IP phases yields a bulk modulus K{sub 0} = 35.3(1.8) GPa. The intralayer CI-CI distances increases, but no change is observed in Fe-CI bond-length nor are there substantial changes in the interlayer spacing. The pressure-induced electronic IP-HP transition leads to a first-order structural phase transition characterized by a decrease in Fe-CI bond length and an abrupt drop in V(P) by {approx}3.5% accompanying the correlation breakdown. In this transition no symmetry change is detected,and the XRD data could be satisfactorily fitted with the CdI{sub 2} structure. The bulk modulus of the HP phase is practically the same as that of the LP-IP phases suggesting negligible changes in the phonon density of state.

  19. Adaptive method with intercessory feedback control for an intelligent agent

    DOE Patents [OSTI]

    Goldsmith, Steven Y.

    2004-06-22T23:59:59.000Z

    An adaptive architecture method with feedback control for an intelligent agent provides for adaptively integrating reflexive and deliberative responses to a stimulus according to a goal. An adaptive architecture method with feedback control for multiple intelligent agents provides for coordinating and adaptively integrating reflexive and deliberative responses to a stimulus according to a goal. Re-programming of the adaptive architecture is through a nexus which coordinates reflexive and deliberator components.

  20. Physiological changes in cultured Sorghum bicolor (L.) Moench cells in response to induced water stress: osmotic potential, relative water content, carbohydrates, organic acids, potassium, and amino acids

    E-Print Network [OSTI]

    Diquez, Ricardo

    1987-01-01T23:59:59.000Z

    UUZEZCLUUZCRL CIIEUEE IE CULTURED ~8OR ICE RICCICR IL ) MOBMCH CELLS IE RESPONSE TO INDUCED WATER STRESS OSMOTIC POTEMTZAL E RELATIVE WATER CONTENT E CARBOHYDRATES U ORGANIC ACIDS@ POTASSIUM E AED AMINO ACIDS A Thesis by RICARDO DIQUEZ... ZN RESPONSB TO IHDUCBD WATBR STRESS'- OSMOTIC POTENTIAL~ RELATIVE WATER CONTENT~ CARBOHYDRATES, ORGANIC ACIDS, POTASSIUM, AND AMINO ACIDS A Thesis by RICARDO DIQUEZ Approved as to style and content by: Roberta H. Smith (Chair of Committee...

  1. Obesity accelerates Helicobacter felis-induced gastric carcinogenesis by enhancing immature myeloid cell trafficking and TH17 response

    E-Print Network [OSTI]

    Ericksen, Russell E.

    Objective: To investigate the role of obesity-associated inflammation and immune modulation in gastric carcinogenesis during Helicobacter-induced chronic gastric inflammation.

  2. Adaptive sequential controller

    DOE Patents [OSTI]

    El-Sharkawi, Mohamed A. (Renton, WA); Xing, Jian (Seattle, WA); Butler, Nicholas G. (Newberg, OR); Rodriguez, Alonso (Pasadena, CA)

    1994-01-01T23:59:59.000Z

    An adaptive sequential controller (50/50') for controlling a circuit breaker (52) or other switching device to substantially eliminate transients on a distribution line caused by closing and opening the circuit breaker. The device adaptively compensates for changes in the response time of the circuit breaker due to aging and environmental effects. A potential transformer (70) provides a reference signal corresponding to the zero crossing of the voltage waveform, and a phase shift comparator circuit (96) compares the reference signal to the time at which any transient was produced when the circuit breaker closed, producing a signal indicative of the adaptive adjustment that should be made. Similarly, in controlling the opening of the circuit breaker, a current transformer (88) provides a reference signal that is compared against the time at which any transient is detected when the circuit breaker last opened. An adaptive adjustment circuit (102) produces a compensation time that is appropriately modified to account for changes in the circuit breaker response, including the effect of ambient conditions and aging. When next opened or closed, the circuit breaker is activated at an appropriately compensated time, so that it closes when the voltage crosses zero and opens when the current crosses zero, minimizing any transients on the distribution line. Phase angle can be used to control the opening of the circuit breaker relative to the reference signal provided by the potential transformer.

  3. Adaptation Plan 

    E-Print Network [OSTI]

    Durnbaugh, A.

    2011-01-01T23:59:59.000Z

    ? Built Environment ? Natural Environment ? People FIVE STRATEGIES Copyright 2011, City of Chicago ADAPTATION ESL-KT-11-11-16 9 CCAP Adaptation Evolution 2007 2008 2009 2010 ? Understood the climate science: Assess climate impacts... E xi st in g Tr un k Existing on Rogers Rogers Ave CIP Stormwater management: Chicago?s comprehensive sewer model Climate impacts Example actions to prepare the built environment Copyright 2011, City of Chicago ESL-KT-11-11-16 13 CCAP...

  4. Mechanics and Applications of Pressure Adaptive Honeycomb

    E-Print Network [OSTI]

    Vos, Roelof

    2009-07-31T23:59:59.000Z

    calculations. In addition, I would like to express my gratitude to the undergraduate students that have helped with the preparations of the experiments: Lauren Kerth, Will Pflug, Tom O?Brien, Thomas Statsny, and Ryan Barnhart. v TABLE OF CONTENTS... and Curvature Induced by Pressure adaptive Honeycomb 55 3.2.1 Pressure adaptive Wing Section 60 3.2.2 Pressure adaptive Gurney Flap 63 3.2.3 Pressure adaptive Solid State Flap 65 3.2.4 Pressure adaptive Engine Inlet 67 vi 3.3 Actuation Sources 71 4.1 Cellular...

  5. Odorant-Induced Olfactory Receptor Neural Oscillations and Their Modulation of Olfactory Bulbar Responses in the Channel Catfish

    E-Print Network [OSTI]

    Stephens, Jacqueline

    origin (Adrian, 1955). Regular voltage oscillations with a frequency of 15­25/sec evident in electroOdorant-Induced Olfactory Receptor Neural Oscillations and Their Modulation of Olfactory Bulbar) in the channel catfish are odorant- induced neural oscillations of synchronized populations of ol- factory

  6. Urban climate resilience : a global assessment of city adaptation plans

    E-Print Network [OSTI]

    Katich, Kristina Noel

    2009-01-01T23:59:59.000Z

    As policy makers accept climate change as an irrefutable threat, adaptation planning has emerged as a necessary action for countries, states, and municipalities. This thesis explores adaptive responses to climate change ...

  7. Adaptive Lighting

    Energy Savers [EERE]

    * ...based on environmental conditions... - Occupancy Vacancy - Daylight Availability - Demand Response Signals - ... * ...to optimize space & building performance - Maximize...

  8. Influence of adaptive mesh refinement and the hydro solver on shear-induced mass stripping in a minor-merger scenario

    E-Print Network [OSTI]

    Schmidt, W; Iapichino, L; Vazza, F; Almgren, A S

    2014-01-01T23:59:59.000Z

    We compare two different codes for simulations of cosmological structure formation to investigate the sensitivity of hydrodynamical instabilities to numerics, in particular, the hydro solver and the application of adaptive mesh refinement (AMR). As a simple test problem, we consider an initially spherical gas cloud in a wind, which is an idealized model for the merger of a subcluster or galaxy with a big cluster. Based on an entropy criterion, we calculate the mass stripping from the subcluster as a function of time. Moreover, the turbulent velocity field is analyzed with a multi-scale filtering technique. We find remarkable differences between the commonly used PPM solver with directional splitting in the Enzo code and an unsplit variant of PPM in the Nyx code, which demonstrates that different codes can converge to systematically different solutions even when using uniform grids. For the test case of an unbound cloud, AMR simulations reproduce uniform-grid results for the mass stripping quite well, although...

  9. H-2 restriction of the T cell response to chemically induced tumors: evidence from F/sub 1/. -->. parent chimeras

    SciTech Connect (OSTI)

    Lannin, D.R.; Yu, S.; McKhann, C.F.

    1982-01-01T23:59:59.000Z

    It has been well established that T cells that react to tumor antigen on virus-induced tumors must share H-2D or H-2K specificities with the tumor. It has been impossible to perform similar studies with chemically induced tumors because each chemically induced tumor expresses a unique tumor antigen that cannot be studied in association with other H-2 types. This study provies evidence that H-2 recognition is also necessary for recognition of chemically induced tumors. We have found that F/sub 1/ ..-->.. parent chimeras preferentially recognize chemically induced tumors of parental H-2 type. C3H/HeJ and C57BL/6 mice were lethally irradiated and restored with (C3H x C57BL/6) F/sub 1/ hybrid bone marrow. The F/sub 1/ ..-->.. C3H chimera but not the F/sub 1/ ..-->.. C57BL/6 chimera was able to respond to a C3H fibrosarcoma in mixed lymphocyte-tumor cell culture and also to neutralize the tumor in an in vivo tumor neutralization assay. On the other hand, the F/sub 1/ ..-->.. C57BL/6 chimera but not the F/sub 1/ ..-->.. C3H chimera was able to kill the C57BL/6 lymphoma EL4 in an in vitro cytotoxicity assay. Both chimeras were tolerant to C3H and C57BL/6 alloantigens but could respond normally to Con A and to BALB/c spleen cells in mixed lymphocyte cultures and cytotoxicity assay.

  10. Adaptation Plan

    E-Print Network [OSTI]

    Durnbaugh, A.

    2011-01-01T23:59:59.000Z

    /pest introduction. Buildings Fa?ade & structural damage. Higher peak electricity demand. Lake Michigan Decreased lake ice in winter & lower lake levels. Greater stress on water resources in times of need. Homes Increased cooling costs & energy... of Chicago ? 2011 ESL-KT-11-11-16 3 Chicago River Promote & incentivize green infrastructure to manage stormwater. Monitor threat of aquatic invasive species. RESILIENCY Adaptation will help reduce the impact of the changes that can be expected...

  11. Adaptive Sampling in Hierarchical Simulation

    SciTech Connect (OSTI)

    Knap, J; Barton, N R; Hornung, R D; Arsenlis, A; Becker, R; Jefferson, D R

    2007-07-09T23:59:59.000Z

    We propose an adaptive sampling methodology for hierarchical multi-scale simulation. The method utilizes a moving kriging interpolation to significantly reduce the number of evaluations of finer-scale response functions to provide essential constitutive information to a coarser-scale simulation model. The underlying interpolation scheme is unstructured and adaptive to handle the transient nature of a simulation. To handle the dynamic construction and searching of a potentially large set of finer-scale response data, we employ a dynamic metric tree database. We study the performance of our adaptive sampling methodology for a two-level multi-scale model involving a coarse-scale finite element simulation and a finer-scale crystal plasticity based constitutive law.

  12. Multi-model adaptive spatial hypertext 

    E-Print Network [OSTI]

    Francisco-Revilla, Luis

    2005-02-17T23:59:59.000Z

    in response to multiple relevant factors. The framework is composed of four parts: a general system architecture, a definition of the fundamental concepts in spatial hypermedia, an ontological classification of the adaptation strategies, and the philosophy...

  13. Skeletal adaptation to reduced mechanical loading

    E-Print Network [OSTI]

    Eliman, Rachel

    2014-01-01T23:59:59.000Z

    Bone adapts its mass and architecture in response to its mechanical environment. Yet control of this process by mechanical cues is poorly understood, particularly for unloading. Defining the fundamental mechanoregulation ...

  14. Cost-effective and highly sensitive cholesterol microsensors with fast response based on the enzyme-induced conductivity change of polyaniline

    SciTech Connect (OSTI)

    Fang, Kuan-Chung; Chu, Chia-Ho; Hsu, Chen-Pin; Kang, Yen-Wen; Fang, Jung-Ying; Chen, Chih-Chen; Li, Sheng-Shian; Andrew Yeh, J.; Yao, Da-Jeng; Wang, Yu-Lin, E-mail: ylwang@mx.nthu.edu.tw [Institute of Nanoengineering and Microsystems, National Tsing Hua University, Hsinchu 300, Taiwan (China); Hsu, Chia-Hsien [Division of Medical Engineering, National Health Research Institutes, MiaoLi, Taiwan (China); Huang, Yu-Fen [Department of Biomedical Engineering and Environmental Science, National Tsing Hua University, Hsinchu 300, Taiwan (China)

    2014-09-15T23:59:59.000Z

    In this study, a cost-effective and highly sensitive cholesterol microsensor, which is consisted of cholesterol oxidase (ChOx), horseradish peroxidase (HRP), and polyaniline (PANI), was developed based on the enzyme-induced conductivity change of PANI with fast response. Hydrogen peroxide is produced via the reaction between cholesterol and ChOx, which was immobilized in a dialysis membrane. The produced hydrogen peroxide can oxidize HRP, which can be reduced by oxidizing PANI, thus resulting in decreased conductivity of the polyaniline thin film. The reduced HRP can be oxidized again by hydrogen peroxide and the cycle of the oxidation/reduction continues until all hydrogen peroxide are reacted, leading to the high sensitivity of the sensor due to the signal contributed from all hydrogen peroxide molecules. Cholesterol was detected near the physiological concentrations ranging from 100?mg/dl to 400?mg/dl with the cholesterol microsensors. The results show linear relation between cholesterol concentration and the conductivity change of the PANI. The microsensor showed no response to cholesterol when the PANI was standalone without cholesterol oxidase immobilized, indicating that the enzymatic reaction is required for cholesterol detection. The simple process of the sensor fabrication allows the sensor to be cost-effective and disposable usage. This electronic cholesterol microsensor is promising for point-of-care health monitoring in cholesterol level with low cost and fast response.

  15. Synthesis and Application of an Environmentally Insensitive Cy3-Based Arsenical Fluorescent Probe to Identify Adaptive Microbial Responses Involving Proximal Dithiol Oxidation

    SciTech Connect (OSTI)

    Fu, Na; Su, Dian; Cort, John R.; Chen, Baowei; Xiong, Yijia; Qian, Weijun; Konopka, Allan; Bigelow, Diana J.; Squier, Thomas C.

    2013-03-06T23:59:59.000Z

    Reversible disulfide oxidation between proximal cysteines in proteins represents a common regulatory control mechanism to modulate flux through metabolic pathways in response to changing environmental conditions. To enable in vivo measurements of cellular redox changes linked to disulfide bond formation, we have synthesized a cell-permeable monosubstituted cyanine dye derivatized with arsenic (i.e., TRAP_Cy3) to trap and visualize dithiols in cytosolic proteins. Alkylation of reactive thiols prior to displacement of the bound TRAP-Cy3 by ethanedithiol permits facile protein capture and mass spectrometric identification of proximal reduced dithiols to the exclusion of individual cysteines. Applying TRAP_Cy3 to evaluate cellular responses to increases in oxygen and light levels in the photosynthetic microbe Synechococcus sp. PCC 7002, we observe large decreases in the abundance of reduced dithiols in cellular proteins, which suggest redox-dependent mechanisms involving the oxidation of proximal disulfides. Under these same growth conditions that result in the oxidation of proximal thiols, there is a reduction in the abundance of post-translational oxidative modifications involving nitrotyrosine and methionine sulfoxide formation. These results suggest that the redox status of proximal cysteines respond to environmental conditions, acting to regulate metabolic flux and minimize the formation of reactive oxygen species to decrease oxidative protein damage.

  16. THYROID HORMONE REVERSES AGING-INDUCED MYOCARDIAL FATTY ACID OXIDATION DEFECTS AND IMPROVES THE RESPONSE TO ACUTELY INCREASED AFTERLOAD

    SciTech Connect (OSTI)

    Ledee, Dolena; Portman, Michael A.; Kajimoto, Masaki; Isern, Nancy G.; Olson, Aaron

    2013-06-07T23:59:59.000Z

    Background: Subclinical hypothyroidism occurs during aging in humans and mice and may contribute to development of heart failure. Aging also impairs myocardial fatty acid oxidation, causing increased reliance on flux through pyruvate dehydrogenase (PDH) to maintain function. We hypothesize that the metabolic changes in aged hearts make them less tolerant to acutely increased work and that thyroid hormone reverses these defects. Methods: Studies were performed on young (Young, 4-6 months) and aged (Old, 22-24 months) C57/BL6 mice at standard (50 mmHg) and high afterload (80 mmHg). Another aged group received thyroid hormone for 3 weeks (Old-TH, high afterload only). Function was measured in isolated working hearts along with substrate fractional contributions (Fc) to the citric acid cycle (CAC) using perfusate with 13C labeled lactate, pyruvate, glucose and unlabeled palmitate and insulin. Results: Cardiac function was similar between Young and Old mice at standard afterload. Palmitate Fc was reduced but no individual carbohydrate contributions differed. CAC and individual substrate fluxes decreased in aged. At high afterload, -dP/dT was decreased in Old versus Young. Similar to low afterload, palmitate Fc was decreased in Old. Thyroid hormone reversed aging-induced changes in palmitate Fc and flux while significantly improving cardiac function. Conclusion: The aged heart shows diminished ability to increase cardiac work due to substrate limitations, primarily impaired fatty acid oxidation. The heart accommodates slightly by increasing efficiency through oxidation of carbohydrate substrates. Thyroid hormone supplementation in aged mice significantly improves cardiac function potentially through restoration of fatty acid oxidation.

  17. Model Driven Mutation Applied to Adaptative Systems Testing

    E-Print Network [OSTI]

    Bartel, Alexandre; Munoz, Freddy; Klein, Jacques; Mouelhi, Tejeddine; Traon, Yves Le

    2012-01-01T23:59:59.000Z

    Dynamically Adaptive Systems modify their behav- ior and structure in response to changes in their surrounding environment and according to an adaptation logic. Critical sys- tems increasingly incorporate dynamic adaptation capabilities; examples include disaster relief and space exploration systems. In this paper, we focus on mutation testing of the adaptation logic. We propose a fault model for adaptation logics that classifies faults into environmental completeness and adaptation correct- ness. Since there are several adaptation logic languages relying on the same underlying concepts, the fault model is expressed independently from specific adaptation languages. Taking benefit from model-driven engineering technology, we express these common concepts in a metamodel and define the operational semantics of mutation operators at this level. Mutation is applied on model elements and model transformations are used to propagate these changes to a given adaptation policy in the chosen formalism. Preliminary resul...

  18. Sensor response rate accelerator

    DOE Patents [OSTI]

    Vogt, Michael C. (Westmont, IL)

    2002-01-01T23:59:59.000Z

    An apparatus and method for sensor signal prediction and for improving sensor signal response time, is disclosed. An adaptive filter or an artificial neural network is utilized to provide predictive sensor signal output and is further used to reduce sensor response time delay.

  19. adapte au petit: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Sciences Websites Summary: par l'extrait suivant : Human-induced climate change is real and beyond. So, given the necessity to adapt to the impacts of these climate...

  20. The effects of age and awareness on prism adaptation 

    E-Print Network [OSTI]

    Roach, Louise

    2007-01-01T23:59:59.000Z

    Neglect patients show a lack of awareness of both the prismatic displacement induced during prism adaptation and of the negative aftereffect they display afterwards. They also show significantly larger aftereffects than ...

  1. Hypochlorous acid and hydrogen peroxide-induced negative regulation of Salmonella enterica serovar Typhimurium ompW by the response regulator ArcA

    E-Print Network [OSTI]

    2012-01-01T23:59:59.000Z

    Hypochlorous acid and hydrogen peroxide-induced negative5. Thomas E: Myeloperoxidase: Hydrogen Peroxide, ChlorideUse the Myeloperoxidase-Hydrogen Peroxide-Chloride System to

  2. A Computational Model for Adaptive Emotion Regulation

    E-Print Network [OSTI]

    Treur, Jan

    A Computational Model for Adaptive Emotion Regulation Tibor Bosse, Matthijs Pontier, and Jan Treur} Abstract. Emotion regulation describes how a subject can use certain strategies to affect emotion response levels. Usually, models for emotion regulation as- sume mechanisms based on feedback loops that indicate

  3. Infection-induced colitis in mice causes dynamic and tissue-specific changes in stress response and DNA damage leading to colon cancer

    E-Print Network [OSTI]

    Mangerich, Aswin

    Helicobacter hepaticus-infected Rag2-/- mice emulate many aspects of human inflammatory bowel disease, including the development of colitis and colon cancer. To elucidate mechanisms of inflammation-induced carcinogenesis, ...

  4. Adaptive protocols for mobile ad hoc networks

    E-Print Network [OSTI]

    Holland, Gavin Douglas

    2005-02-17T23:59:59.000Z

    . We investigate new link layer mechanisms that dynamically monitor and adapt to changes in link quality, including a protocol that uses common control messages to form a tight feedback control loop for adaptation of the link data rate to best match... of the presence of multirate links. We then investigate the performance of iv TCP, showing how communication outages caused by link failures and routing delays can be very detrimental to its performance. In response, we present a solution to this problem that uses...

  5. Adaptive Street Lighting Controls

    Broader source: Energy.gov [DOE]

    This two-part DOE Municipal Solid-State Street Lighting Consortium webinar focused on LED street lighting equipped with adaptive control components. In Part I, presenters Amy Olay of the City of...

  6. Climate Change Adaptation Planning

    Office of Energy Efficiency and Renewable Energy (EERE)

    This course provides an introduction to planning for climate change impacts, with examples of tribes that have been going through the adaptation planning process. The course is intended for tribal...

  7. Discriminative Adaptive Training and Bayesian Inference for

    E-Print Network [OSTI]

    de Gispert, Adrià

    adaptation is a standard part of many speech recognition systems. This process requires some adaptation data

  8. Organizational Adaptation Kathleen M. Carley

    E-Print Network [OSTI]

    Sadeh, Norman M.

    Organizational Adaptation Kathleen M. Carley Dept. of Social and Decision Sciences Carnegie Mellon: Kathleen M. Carley, 1998, "Organizational Adaptation." Annals of Operations Research. 75: 25-47. #12;Organizational Adaptation A computational model of organizational adaptation in which change occurs at both

  9. Carbon dioxide effects research and assessment program. Environmental and societal consequences of a possible CO/sub 2/-induced climate change: volume II, part I. Response of the West Antarctic ice sheet to CO/sub 2/-induced climatic warming

    SciTech Connect (OSTI)

    Bentley, C.

    1982-04-01T23:59:59.000Z

    The paper proposes a research plan to deal with the question of what the response of the West Antarctic Ice Sheet would be to a rise in global temperatures caused by an anthropogenic CO/sub 2/ buildup in the atmosphere. The plan is designed to answer the following questions: (1) how fast is the ice mass changing now, and why; (2) how will the boundary conditions that affect the ice sheet respond to an atmospheric temperature change and how are those boundary conditions changing now; (3) what will be the response of the ice sheet to changes in boundary conditions; and (4) what can be learned by analogy with what has happened in the past. (ACR)

  10. Lymphatic Functional Adaptations to Prolonged Changes in Mechanical Stimuli

    E-Print Network [OSTI]

    Nguyen, Tam L

    2013-03-21T23:59:59.000Z

    ). The adaptive responses first reported in the present work, are thus consistent with an accepted understanding of interstitial volume regulation (4). 3.1.3b. Strengths of the experimental model The difficulty in studying adaptation of blood vessels..., one end of a fluid-filled tube (Tygon R3603, Saint- Gobain Performance Plastic, Garden Grove, CA) was inserted through the wall of the vein while the other end was brought outside of the animal. Exteriorized intestine and mesentery were...

  11. Adaptive Medical Information Delivery Combining User, Task and Situation Models

    E-Print Network [OSTI]

    ., in their model for adaptive hypermedia AHAM [2], distinguish content­adaptation from link­ adaptation

  12. A MATHEMATICAL FRAMEWORK FOR THE LINEAR RECONSTRUCTOR PROBLEM IN ADAPTIVE OPTICS

    E-Print Network [OSTI]

    A MATHEMATICAL FRAMEWORK FOR THE LINEAR RECONSTRUCTOR PROBLEM IN ADAPTIVE OPTICS MOODY T. CHU aberrations induced by atmospheric turbulence can severely de­ grade the performance of an optical imaging system. Adaptive optics refers to the process of removing unwanted wave front distortions in real time, i

  13. A MATHEMATICAL FRAMEWORK FOR THE LINEAR RECONSTRUCTOR PROBLEM IN ADAPTIVE OPTICS

    E-Print Network [OSTI]

    A MATHEMATICAL FRAMEWORK FOR THE LINEAR RECONSTRUCTOR PROBLEM IN ADAPTIVE OPTICS MOODY T. CHU induced by atmospheric turbulence can severely de- grade the performance of an optical imaging system. Adaptive optics refers to the process of removing unwanted wave front distortions in real time, i

  14. The cardiokine story unfolds: ischemic stress-induced protein secretion

    E-Print Network [OSTI]

    Glembotski, Christopher

    on secreted proteins to mount a response designed to resist stress-induced damage. This review examines

  15. Global transcriptome analysis of the heat shock response ofshewanella oneidensis

    SciTech Connect (OSTI)

    Gao, Haichun; Wang, Sarah; Liu, Xueduan; Yan, Tinfeng; Wu, Liyou; Alm, Eric; Arkin, Adam P.; Thompson, Dorothea K.; Zhou, Jizhong

    2004-04-30T23:59:59.000Z

    Shewanella oneidensis is an important model organism for bioremediation studies because of its diverse respiratory capabilities. However, the genetic basis and regulatory mechanisms underlying the ability of S. oneidensis to survive and adapt to various environmentally relevant stresses is poorly understood. To define this organism's molecular response to elevated growth temperatures, temporal gene expression profiles were examined in cells subjected to heat stress using whole-genome DNA microarrays for S. oneidensis MR-1. Approximately 15 percent (711) of the predicted S. oneidensis genes represented on the microarray were significantly up- or down-regulated (P < 0.05) over a 25-min period following shift to the heat shock temperature (42 C). As expected, the majority of S. oneidensis genes exhibiting homology to known chaperones and heat shock proteins (Hsps) were highly and transiently induced. In addition, a number of predicted genes encoding enzymes in glycolys is and the pentose cycle, [NiFe] dehydrogenase, serine proteases, transcriptional regulators (MerR, LysR, and TetR families), histidine kinases, and hypothetical proteins were induced in response to heat stress. Genes encoding membrane proteins were differentially expressed, suggesting that cells possibly alter their membrane composition or structure in response to variations in growth temperature. A substantial number of the genes encoding ribosomal proteins displayed down-regulated co-expression patterns in response to heat stress, as did genes encoding prophage and flagellar proteins. Finally, based on computational comparative analysis of the upstream promoter regions of S.oneidensis heat-inducible genes, a putative regulatory motif, showing high conservation to the Escherichia coli sigma 32-binding consensus sequence, was identified.

  16. CONTRIBUTED Adaptive Stochastic Control

    E-Print Network [OSTI]

    Powell, Warren B.

    sources, many forms of energy storage, and microgrid management (see Fig. 1). Computationally, controlling of distributed generation and storage within the Smart Grid. KEYWORDS | Adaptive stochastic control (ASC.g., factory assembly lines, petrochemical plants, and nuclear power plants). Below we describe

  17. Energy dissipation in an adaptive molecular circuit

    E-Print Network [OSTI]

    Shou-Wen Wang; Yueheng Lan; Lei-Han Tang

    2015-05-28T23:59:59.000Z

    The ability to monitor nutrient and other environmental conditions with high sensitivity is crucial for cell growth and survival. Sensory adaptation allows a cell to recover its sensitivity after a transient response to a shift in the strength of extracellular stimulus. The working principles of adaptation have been established previously based on rate equations which do not consider fluctuations in a thermal environment. Recently, G. Lan et al. (Nature Phys., 8:422-8, 2012) performed a detailed analysis of a stochastic model for the E. coli sensory network. They showed that accurate adaptation is possible only when the system operates in a nonequilibrium steady-state (NESS). They further proposed an energy-speed-accuracy (ESA) trade-off relation. We present here analytic results on the NESS of the model through a mapping to a one-dimensional birth-death process. An exact expression for the entropy production rate is also derived. Based on these results, we are able to discuss the ESA relation in a more general setting. Our study suggests that the adaptation error can be reduced exponentially as the methylation range increases. Finally, we show that a nonequilibrium phase transition exists in the infinite methylation range limit, despite the fact that the model contains only two discrete variables.

  18. Response of a tundra ecosystem to elevated atmospheric carbon dioxide and CO{sub 2}-induced climate change. Annual technical report

    SciTech Connect (OSTI)

    Oechel, W.C.

    1992-04-01T23:59:59.000Z

    Northern ecosystems contain up to 455 Gt of C in the soil active layer and upper permafrost. The soil carbon in these layers is equivalent to approximately 60% of the carbon currently in the atmosphere as CO{sub 2}. Much of this carbon is stored in the soil as dead organic matter. Its fate is subject to the net effects of global change on the plant and soil systems of northern ecosystems. The arctic alone contains about 60 Gt C, 90% of which is present in the soil active layer and upper permafrost. The arctic is assumed to have been a sink for CO{sub 2} during the historic and recent geologic past. The arctic has the potential to be a very large, long-term source or sink of CO{sub 2} with respect to the atmosphere. In situ experimental manipulations of atmospheric CO{sub 2}, indicated that there is little effect of elevated atmospheric CO{sub 2} on leaf level photosynthesis or whole-ecosystem CO{sub 2} flux over the course of weeks to years, respectively. However, there may be longer- term ecosystem responses to elevated CO{sub 2} that could ultimately affect ecosystem CO{sub 2} balance. In addition to atmospheric CO{sub 2}, climate may affect net ecosystem carbon balance. Recent results indicate that the arctic has become a source of CO{sub 2} to the atmosphere. This change coincides with recent climatic variation in the arctic, and suggests a positive feedback of arctic ecosystems on atmospheric CO{sub 2} and global change. The research proposed in this application has four principal aspects: (A) Long-term response of arctic plants and ecosystems to elevated atmospheric CO{sub 2}; (B) Circumpolar patterns of net ecosystem CO{sub 2} flux; (C) In situ controls by temperature and moisture on net ecosystem CO{sub 2} flux; (D) Scaling of CO{sub 2} flux from plot, to landscape, to regional scales (In conjunction with research proposed for NSF support).

  19. Climate Change, Adaptation, and Development

    E-Print Network [OSTI]

    Cole, Daniel H.

    2008-01-01T23:59:59.000Z

    Climate Change, Adaptation, and Development Daniel H. Cole*THE COSTS OF CLIMATE CHANGE . ADAPTATIONCONVENTION ON CLIMATE CHANGE . IV. A.

  20. Id-1 is induced in MDCK epithelial cells by activated Erk/MAPK pathway in response to expression of the Snail and E47 transcription factors

    SciTech Connect (OSTI)

    Jorda, Mireia [IDIBELL-Institut de Recerca Oncologica, Centre d'Oncologia Molecular, Barcelona (Spain); Vinyals, Antonia [IDIBELL-Institut de Recerca Oncologica, Centre d'Oncologia Molecular, Barcelona (Spain); Marazuela, Anna [IDIBELL-Institut de Recerca Oncologica, Centre d'Oncologia Molecular, Barcelona (Spain); Cubillo, Eva [Instituto de Investigaciones Biomedicas 'Alberto Sols' (CSIC-UAM) and Departamento de Bioquimica (UAM), Madrid (Spain); Olmeda, David [Instituto de Investigaciones Biomedicas 'Alberto Sols' (CSIC-UAM) and Departamento de Bioquimica (UAM), Madrid (Spain); Valero, Eva [IDIBELL-Institut de Recerca Oncologica, Centre d'Oncologia Molecular, Barcelona (Spain); Cano, Amparo [Instituto de Investigaciones Biomedicas 'Alberto Sols' (CSIC-UAM) and Departamento de Bioquimica (UAM), Madrid (Spain); Fabra, Angels [IDIBELL-Institut de Recerca Oncologica, Centre d'Oncologia Molecular, Barcelona (Spain)]. E-mail: afabra@idibell.org

    2007-07-01T23:59:59.000Z

    Id-1, a member of the helix-loop-helix transcription factor family has been shown to be involved in cell proliferation, angiogenesis and invasion of many types of human cancers. We have previously shown that stable expression of E47 and Snail repressors of the E-cadherin promoter in MDCK epithelial cell line triggers epithelial mesenchymal transition (EMT) concomitantly with changes in gene expression. We show here that both factors activate the Id-1 gene promoter and induce Id-1 mRNA and protein. The upregulation of the Id-1 gene occurs through the transactivation of the promoter by the Erk/MAPK signaling pathway. Moreover, oncogenic Ras is also able to activate Id-1 promoter in MDCK cells in the absence of both E47 and Snail transcription factors. Several transcriptionally active regulatory elements have been identified in the proximal promoter, including AP-1, Sp1 and four putative E-boxes. By EMSA, we only detected an increased binding to Sp1 and AP-1 elements in E47- and Snail-expressing cells. Binding is affected by the treatment of cells with PD 98059 MEK inhibitor, suggesting that MAPK/Erk contributes to the recruitment or assembly of proteins to Id-1 promoter. Small interfering RNA directed against Sp1 reduced Id-1 expression and the upregulation of the promoter, indicating that Sp1 is required for Id-1 induction in E47- and Snail-expressing cells. Our results provide new insights into how some target genes are activated during and/or as a consequence of the EMT triggered by both E47 and Snail transcription factors.

  1. Biomarker Response to Galactic Cosmic Ray-Induced NOx and the Methane Greenhouse Effect in the Atmosphere of an Earthlike Planet Orbiting an M-Dwarf Star

    E-Print Network [OSTI]

    Grenfell, J L; Patzer, B; Rauer, H; Segura, A; Stadelmann, A; Stracke, B; Titz, R; Von Paris, P; Grenfell, John Lee; Griessmeier, Jean-Mathias; Patzer, Beate; Rauer, Heike; Segura, Antigona; Stadelmann, Anja; Stracke, Barbara; Titz, Ruth; Paris, Philip von

    2007-01-01T23:59:59.000Z

    Planets orbiting in the habitable zone (HZ) of M-Dwarf stars are subject to high levels of galactic cosmic rays (GCRs) which produce nitrogen oxides in earthlike atmospheres. We investigate to what extent this NOx may modify biomarker compounds such as ozone (O3) and nitrous oxide (N2O), as well as related compounds such as water (H2O) (essential for life) and methane (CH4) (which has both abiotic and biotic sources) . Our model results suggest that such signals are robust, changing in the M-star world atmospheric column by up to 20% due to the GCR NOx effects compared to an M-star run without GCR effects and can therefore survive at least the effects of galactic cosmic rays. We have not however investigated stellar cosmic rays here. CH4 levels are about 10 times higher than on the Earth related to a lowering in hydroxyl (OH) in response to changes in UV. The increase is less than reported in previous studies. This difference arose partly because we used different biogenic input. For example, we employed 23% ...

  2. ON ADAPTIVE SAMPLING Philippe Flajolet

    E-Print Network [OSTI]

    Flajolet, Philippe

    . We analyze the storage/accuracy trade--off of an adaptive sampling algorithm due to Wegman that makes. Wegman [11] has proposed an interesting alternative solution to that problem based on Adaptive Sampling 4. 2 Wegman's Adaptive Sampling Method The problem discussed here is the following. We are given

  3. Biomarker Response to Galactic Cosmic Ray-Induced NOx and the Methane Greenhouse Effect in the Atmosphere of an Earthlike Planet Orbiting an M-Dwarf Star

    E-Print Network [OSTI]

    John Lee Grenfell; Jean-Mathias Griessmeier; Beate Patzer; Heike Rauer; Antigona Segura; Anja Stadelmann; Barbara Stracke; Ruth Titz; Philip von Paris

    2007-02-23T23:59:59.000Z

    Planets orbiting in the habitable zone (HZ) of M-Dwarf stars are subject to high levels of galactic cosmic rays (GCRs) which produce nitrogen oxides in earthlike atmospheres. We investigate to what extent this NOx may modify biomarker compounds such as ozone (O3) and nitrous oxide (N2O), as well as related compounds such as water (H2O) (essential for life) and methane (CH4) (which has both abiotic and biotic sources) . Our model results suggest that such signals are robust, changing in the M-star world atmospheric column by up to 20% due to the GCR NOx effects compared to an M-star run without GCR effects and can therefore survive at least the effects of galactic cosmic rays. We have not however investigated stellar cosmic rays here. CH4 levels are about 10 times higher than on the Earth related to a lowering in hydroxyl (OH) in response to changes in UV. The increase is less than reported in previous studies. This difference arose partly because we used different biogenic input. For example, we employed 23% lower CH4 fluxes compared to those studies. Unlike on the Earth, relatively modest changes in these fluxes can lead to larger changes in the concentrations of biomarker and related species on the M-star world. We calculate a CH4 greenhouse heating effect of up to 4K. O3 photochemistry in terms of the smog mechanism and the catalytic loss cycles on the M-star world differs considerably compared with the Earth.

  4. Response of a tundra ecosystem to elevated atmospheric carbon dioxide and CO{sub 2}-induced climate change. Annual technical report

    SciTech Connect (OSTI)

    Oechel, W.C.

    1993-02-01T23:59:59.000Z

    Northern ecosystems contain up to 455 Gt of C in the soil active layer and upper permafrost, which is equivalent to approximately 60% of the carbon currently in the atmosphere as CO{sub 2}. Much of this carbon is stored in the soil as dead organic matter. Its fate is subject to the net effects of global change on the plant and soil systems of northern ecosystems. The arctic alone contains about 60 Gt C, 90% of which is present in the soil active layer and upper permafrost, and is assumed to have been a sink for CO{sub 2} during the historic and recent geologic past. Depending on the nature, rate, and magnitude of global environmental change, the arctic may have a positive or negative feedback on global change. Results from the DOE- funded research efforts of 1990 and 1991 indicate that the arctic has become a source of CO{sub 2} to the atmosphere. Measurements made in the Barrow, Alaska region during 1992 support these results. This change coincides with recent climatic variation in the arctic, and suggests a positive feedback of arctic ecosystems on atmospheric CO{sub 2} and global change. There are obvious potential errors in scaling plot level measurements to landscape, mesoscale, and global spatial scales. In light of the results from the recent DOE-funded research, and the remaining uncertainties regarding the change in arctic ecosystem function due to high latitude warming, a revised set of research goals is proposed for the 1993--94 year. The research proposed in this application has four principal aspects: (A) Long- term response of arctic plants and ecosystems to elevated atmospheric CO{sub 2}. (B) Circumpolar patterns of net ecosystem CO{sub 2} flux. (C) In situ controls by temperature and moisture on net ecosystem CO{sub 2} flux. (D) Scaling of CO{sub 2} flux from plot, to landscape, to regional scales.

  5. Adaptive control for accelerators

    DOE Patents [OSTI]

    Eaton, Lawrie E. (Los Alamos, NM); Jachim, Stephen P. (Los Alamos, NM); Natter, Eckard F. (Santa Fe, NM)

    1991-01-01T23:59:59.000Z

    An adaptive feedforward control loop is provided to stabilize accelerator beam loading of the radio frequency field in an accelerator cavity during successive pulses of the beam into the cavity. A digital signal processor enables an adaptive algorithm to generate a feedforward error correcting signal functionally determined by the feedback error obtained by a beam pulse loading the cavity after the previous correcting signal was applied to the cavity. Each cavity feedforward correcting signal is successively stored in the digital processor and modified by the feedback error resulting from its application to generate the next feedforward error correcting signal. A feedforward error correcting signal is generated by the digital processor in advance of the beam pulse to enable a composite correcting signal and the beam pulse to arrive concurrently at the cavity.

  6. An Extensible, Lightweight Architecture for Adaptive J2EE Applications

    SciTech Connect (OSTI)

    Gorton, Ian; Liu, Yan; Trivedi, Nihar

    2006-11-01T23:59:59.000Z

    Server applications with adaptive behaviors can adapt their functionality in response to environmental changes, and significantly reduce the on-going costs of system deployment and administration. However, developing adaptive server applications is challenging due to the complexity of server technologies and highly dynamic application environments. This paper presents an architecture framework, known as the Adaptive Server Framework (ASF). ASF provides a clear separation between the implementation of adaptive behaviors and the server application business logic. This means a server application can be cost effectively extended with programmable adaptive features through the definition and implementation of control components defined in ASF. Further-more, ASF is a lightweight architecture in that it incurs low CPU overhead and memory usage. We demonstrate the effectiveness of ASF through a case study, in which a server application dynamically determines the resolution and quality to scale an image based on the load of the server and network connection speed. The experimental evaluation demonstrates the performance gains possible by adaptive behaviors and the low overhead introduced by ASF.

  7. Rendering Adaptation to Address Communication and Computation Constraints in Cloud Mobile Gaming

    E-Print Network [OSTI]

    California at San Diego, University of

    Rendering Adaptation to Address Communication and Computation Constraints in Cloud Mobile Gaming the responsibility of executing the gaming engines, including the most compute intensive tasks of graphic rendering imposed by the cost and availability of cloud servers. In this paper, we propose a rendering adaptation

  8. Demand Response for Ancillary Services

    SciTech Connect (OSTI)

    Alkadi, Nasr E [ORNL; Starke, Michael R [ORNL

    2013-01-01T23:59:59.000Z

    Many demand response resources are technically capable of providing ancillary services. In some cases, they can provide superior response to generators, as the curtailment of load is typically much faster than ramping thermal and hydropower plants. Analysis and quantification of demand response resources providing ancillary services is necessary to understand the resources economic value and impact on the power system. Methodologies used to study grid integration of variable generation can be adapted to the study of demand response. In the present work, we describe and illustrate a methodology to construct detailed temporal and spatial representations of the demand response resource and to examine how to incorporate those resources into power system models. In addition, the paper outlines ways to evaluate barriers to implementation. We demonstrate how the combination of these three analyses can be used to translate the technical potential for demand response providing ancillary services into a realizable potential.

  9. Complex Adaptive System of Systems (CASoS) Engineering Initiative

    E-Print Network [OSTI]

    ://www.sandia.gov/CasosEngineering/ SAND 2011-3354 P Complex Adaptive Systems of Systems (CASoS) E i i M i A i ti t P bl. · Recover or Change in response to events. · Control system behavior to avoid or steer the system towardsy y

  10. Essays on Agricultural Adaptation to Climate Change and Ethanol Market Integration in the U.S.

    E-Print Network [OSTI]

    Aisabokhae, Ruth 1980-

    2012-12-05T23:59:59.000Z

    to reduce the current and future extent of climate change. Biofuels production, for instance, expands agriculture’s role in climate change mitigation. This dissertation encompasses adaptation and mitigation strategies as a response to climate change...

  11. Making climate adaptation work : strategies for resource constrained South Asian mega-cities

    E-Print Network [OSTI]

    Dutta-Koehler, Madhu Chhanda

    2013-01-01T23:59:59.000Z

    This dissertation compares the responses of Dhaka, Bangladesh and Kolkata, India to the serious challenges posed by climate change, particularly in the water sector. Drawing on the theories of "adaptation as development" ...

  12. Adapting to Survive

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041cloth DocumentationProducts (VAP) VAP7-0973 1 IntroductionActinide ChemistryActivitiesAdapting to

  13. Adaptive Energy Grid

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041cloth DocumentationProducts (VAP) VAP7-0973 1 IntroductionActinide ChemistryActivitiesAdapting

  14. BRIDGING NAVIGATION, SEARCH AND ADAPTATION. Adaptive Hypermedia Models Evolution

    E-Print Network [OSTI]

    De Bra, Paul

    Corpus, Dexter Model, AHAM, GAF. Abstract: Adaptive Hypermedia Systems (AHS) have long been concentrating The most referenced (but certainly not only) Adaptive Hypermedia (AH) model dates back to 1999. Since AHAM/Hypermedia modelling from Dexter Model through AHAM to the proposed GAF model, out- line advantages of each framework

  15. Hierarchy-Direction Selective Approach for Locally Adaptive Sparse Grids

    SciTech Connect (OSTI)

    Stoyanov, Miroslav K [ORNL

    2013-09-01T23:59:59.000Z

    We consider the problem of multidimensional adaptive hierarchical interpolation. We use sparse grids points and functions that are induced from a one dimensional hierarchical rule via tensor products. The classical locally adaptive sparse grid algorithm uses an isotropic refinement from the coarser to the denser levels of the hierarchy. However, the multidimensional hierarchy provides a more complex structure that allows for various anisotropic and hierarchy selective refinement techniques. We consider the more advanced refinement techniques and apply them to a number of simple test functions chosen to demonstrate the various advantages and disadvantages of each method. While there is no refinement scheme that is optimal for all functions, the fully adaptive family-direction-selective technique is usually more stable and requires fewer samples.

  16. Impedance response to induced epileptiform discharges

    E-Print Network [OSTI]

    Gerber, Terry Lynn

    1984-01-01T23:59:59.000Z

    in the development of an early-warning seizure detector. Such a detector would be design- ed to help the over two million individuals in the United States who are afflicted with epilepsy and cannot be significantly helped with standard treatment methods... to lead a more normal life, a preliminary study to develop an early-warning seizure detector was un- dertaken by Marquardt that could alert the patient of an impending at- tack (10). Several devices that detect seizure onset and one that at- tempts...

  17. Fire-induced growth responses of huisache

    E-Print Network [OSTI]

    Rasmussen, George Allen

    1981-01-01T23:59:59.000Z

    . Briske, Dr. D. L. Drawe, and Dr. W. G. Swank for their suggestions and assistance throughout tnIs study. Personal thanks to the Pob and. Bessie Welder Wildlife Foundation for providing financis1 support az d tne study area. Special thanks to tne range... 1961). There is an inverse relationship between the hydration of the plant protoplasm and resistance to heat and cold (Larcher 1975). MATERIALS AND METHODS S te Description The study area is located on the Rob and Bessie Welder Wildlife Founcation...

  18. Wind-induced dynamic response of bridges

    E-Print Network [OSTI]

    Rousseau, Guillaume, 1982-

    2004-01-01T23:59:59.000Z

    Wind loading has long played a significant role in bridge design. Some spectacular failures, such as the Tay Bridge (Scotland, 1879), or the Tacoma Narrows Bridge (Washington State, 1940) acted as a painful reminder to ...

  19. I. INTRODUCTION Hierarchical Adaptive Kalman

    E-Print Network [OSTI]

    Ghosh, Joydeep

    I. INTRODUCTION Hierarchical Adaptive Kalman Filtering for Interplanetary Orbit Determination of Texas at Austin A modular and flexibleapproach to adaptive Kalman filtering has recently been introduced using the framework of a mixture-of-experts regulated by a gating network. Each expert is a Kalman

  20. Adaptation, Learning, and Optimization over

    E-Print Network [OSTI]

    California at Los Angeles, University of

    Adaptation, Learning, and Optimization over Networks Ali H. Sayed University of California at Los 2014 A. H. Sayed DOI: 10.1561/2200000051 Adaptation, Learning, and Optimization over Networks Ali H . . . . . . . . . . . . . . . . . . . . . . . . . 7 1.6 Notation and Symbols . . . . . . . . . . . . . . . . . . . . 8 2 Optimization by Single Agents

  1. Adaptive Optics in Star Formation

    E-Print Network [OSTI]

    Wolfgang Brandner

    2003-09-29T23:59:59.000Z

    Over the past ten years, the concept of adaptive optics has evolved from early experimental stages to a standard observing tool now available at almost all major optical and near-infrared telescope facilities. Adaptive optics will also be essential in exploiting the full potential of the large optical/infrared interferometers currently under construction. Both observations with high-angular resolution and at high contrast, and with a high point source sensitivity are facilitated by adaptive optics. Among the areas which benefit most from the use of adaptive optics are studies of the circumstellar environment (envelopes, disks, outflows), substellar companions and multiple systems, and dense young stellar populations. This contribution highlights some of the recent advances in star formation studies facilitated by adaptive optics, and gives a brief tutorial on optimized observing and data reduction strategies.

  2. Adaptive excitation control in power systems

    E-Print Network [OSTI]

    Chiu, Pei-Chen

    2006-08-16T23:59:59.000Z

    This thesis presents an adaptive excitation controller of power systems. The control law is derived by using model reference adaptive control (MRAC) or adaptive pole placement control (APPC) and an equilibrium tracking mechanism is implemented...

  3. adaptive response ar: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AR Representation AR Results Conclusion References Automated Reasoning in Modal Logics: A Framework with Applications Branden Fitelson Department of Philosophy Institute for...

  4. adaptive melanin response: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and Sustainability. In February 2013, Athens of students to be future generators of sustainable value for business and society at large and to work Chatziantoniou, Damianos...

  5. adaptive metabolic response: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    appear to be the structural manifestation of this cellular metabolic memory. Here, a new framework for molecular information storage in the cell is presented, which is...

  6. adaptive gene responses: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and Sustainability. In February 2013, Athens of students to be future generators of sustainable value for business and society at large and to work Chatziantoniou, Damianos...

  7. Adaptable architecture : a computational exploration into responsive design systems

    E-Print Network [OSTI]

    Zulas, Alejandro, 1976-

    2004-01-01T23:59:59.000Z

    Based on the fact that architecture is, among other things, the crystallization of a mediation among design intentions (function), meaning and contextual constraints (performance), we as designers are obligated to produce ...

  8. Automated Grid Disruption Response System: Robust Adaptive Topology Control (RATC)

    SciTech Connect (OSTI)

    None

    2012-03-01T23:59:59.000Z

    GENI Project: The RATC research team is using topology control as a mechanism to improve system operations and manage disruptions within the electric grid. The grid is subject to interruption from cascading faults caused by extreme operating conditions, malicious external attacks, and intermittent electricity generation from renewable energy sources. The RATC system is capable of detecting, classifying, and responding to grid disturbances by reconfiguring the grid in order to maintain economically efficient operations while guaranteeing reliability. The RATC system would help prevent future power outages, which account for roughly $80 billion in losses for businesses and consumers each year. Minimizing the time it takes for the grid to respond to expensive interruptions will also make it easier to integrate intermittent renewable energy sources into the grid.

  9. Cellular Response to Ordered Collagen Layers on Mica

    E-Print Network [OSTI]

    Leow, Wee Wen

    2012-07-16T23:59:59.000Z

    matrix (ECM), whereby cells are constantly sensing and modifying their surroundings in response to physical stress or during processes like wound repair, cancer cell invasion, and morphogenesis, to create an environment which supports adaptation. To date...

  10. A Dynamic Platform for Runtime Adaptation

    E-Print Network [OSTI]

    Pham, Hubert

    We present a middleware platform for assembling pervasive applications that demand fault-tolerance and adaptivity in distributed, dynamic environments. Unlike typical adaptive middleware approaches, in which sophisticated ...

  11. An Adaptive Voltage Control Algorithm with Multiple Distributed Energy

    SciTech Connect (OSTI)

    Li, Huijuan [University of Tennessee, Knoxville (UTK); Li, Fangxing [ORNL; Adhikari, Sarina [ORNL; Xu, Yan [ORNL; Rizy, D Tom [ORNL; Kueck, John D [ORNL

    2009-01-01T23:59:59.000Z

    Distributed energy resources (DE) with power electronics (PE) interfaces with the right control are capable of providing reactive power related ancillary services. Voltage regulation in particular has drawn much attention. In this paper the challenges to control multiple DEs to regulate the local voltage in distribution systems is addressed and a decentralized adaptive voltage control method is proposed. The simulation results in different system conditions show that this adaptive voltage control method is capable of satisfying the fast response speed requirement without causing oscillation or instability of the system. Since this method has high tolerance to the shortage of the system parameters and can be widely adaptive to the variable operation situations of the power systems, it is very suited for the utility application.

  12. Mutations in Global Regulators Lead to Metabolic Selection during Adaptation to Complex Environments

    SciTech Connect (OSTI)

    Saxer, Gerda; Krepps, Michael D.; Merkley, Eric D.; Ansong, Charles; Kaiser, Brooke LD; Valovska, Marie-Thrse; Ristic, Nikola; Yeh, Ping T.; Prakash, Vittal; Leiser, Owen P.; Nakhleh, Luay; Gibbons, Henry S.; Kreuzer, Helen W.; Shamoo, Yousif

    2014-12-11T23:59:59.000Z

    Adaptation to ecologically complex environments can provide insights into the evolutionary dynamics and functional constraints encountered by organisms during natural selection. Unlike adaptation to a single limiting resource, adaptation to a new environment with abundant and varied resources can be difficult to achieve by small incremental changes since many mutations are required to achieve even modest gains in fitness. Since changing complex environments are quite common in nature, we investigated how such an epistatic bottleneck can be avoided to allow rapid adaptation. We show that adaptive mutations arise repeatedly in independently evolved populations in the context of greatly increased genetic and phenotypic diversity. We go on to show that weak selection requiring substantial metabolic reprogramming can be readily achieved by mutations in the global response regulator arcA and the stress response regulator rpoS. We identified 46 unique single-nucleotide variants of arcA and 18 mutations in rpoS, nine of which resulted in stop codons or large deletions, suggesting that a subtle modulation of ArcA function and knockouts of rpoS are largely responsible for the metabolic shifts leading to adaptation. These mutations allow a higher order “metabolic selection” that eliminates epistatic bottlenecks, which could occur when many changes would be required. Proteomic and carbohydrate analysis of adapting E. coli populations revealed an up-regulation of enzymes associated with the TCA cycle and amino acid metabolism and an increase in the secretion of putrescine. The overall effect of adaptation across populations is to redirect and efficiently utilize uptake and catabolism of abundant amino acids. Concomitantly, there is a pronounced spread of more ecologically limited strains that results from specialization through metabolic erosion. Remarkably, the global regulators arcA and rpoS can provide a “one-step” mechanism of adaptation to a novel environment, which highlights the importance of global resource management as a powerful strategy to adaptation.

  13. Climate Change, Adaptation, and Development

    E-Print Network [OSTI]

    Cole, Daniel H.

    2008-01-01T23:59:59.000Z

    adaptive efficiency in some LDC economies. At this point,capacity-building" in LDC parties. 22 Addition- ally, twoof the over-dependence of many LDC economies on sectors that

  14. Adaptive multiconfigurational wave functions

    SciTech Connect (OSTI)

    Evangelista, Francesco A., E-mail: francesco.evangelista@emory.edu [Department of Chemistry and Cherry L. Emerson Center for Scientific Computation, Emory University, Atlanta, Georgia 30322 (United States)

    2014-03-28T23:59:59.000Z

    A method is suggested to build simple multiconfigurational wave functions specified uniquely by an energy cutoff ?. These are constructed from a model space containing determinants with energy relative to that of the most stable determinant no greater than ?. The resulting ?-CI wave function is adaptive, being able to represent both single-reference and multireference electronic states. We also consider a more compact wave function parameterization (?+SD-CI), which is based on a small ?-CI reference and adds a selection of all the singly and doubly excited determinants generated from it. We report two heuristic algorithms to build ?-CI wave functions. The first is based on an approximate prescreening of the full configuration interaction space, while the second performs a breadth-first search coupled with pruning. The ?-CI and ?+SD-CI approaches are used to compute the dissociation curve of N{sub 2} and the potential energy curves for the first three singlet states of C{sub 2}. Special attention is paid to the issue of energy discontinuities caused by changes in the size of the ?-CI wave function along the potential energy curve. This problem is shown to be solvable by smoothing the matrix elements of the Hamiltonian. Our last example, involving the Cu{sub 2}O{sub 2}{sup 2+} core, illustrates an alternative use of the ?-CI method: as a tool to both estimate the multireference character of a wave function and to create a compact model space to be used in subsequent high-level multireference coupled cluster computations.

  15. Exploring scaling up community-based adaptation: A case study with the PRODUCE Project in Rangpur, Bangladesh 

    E-Print Network [OSTI]

    Harsoyo, Dwi, L. R.

    2012-11-29T23:59:59.000Z

    is an approach to respond to these immediate impacts by adjusting the natural or human systems in response to actual impacts of climate change. Community-based adaptation (CBA) is a bottom-up and development-oriented view of adaptation that accommodates...

  16. Type 2 diabetes severely impairs structural and functional adaptation of rat resistance arteries to chronic changes in blood flow

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    1 Type 2 diabetes severely impairs structural and functional adaptation of rat resistance arteries : Diabetes impairs flow-mediated remodeling Address for Correspondence: Dr. Daniel Henrion, Pharm.D., Ph damages in type 2 diabetes. The capacity of the microcirculation to adapt or remodel in response

  17. Matrix adaptation in discriminative vector quantization

    E-Print Network [OSTI]

    Zachmann, Gabriel

    . Gabriel Zachmann (Computer Graphics) #12;Matrix adaptation in discriminative vector quantization Petra

  18. Enhanced electrocaloric and pyroelectric response from ferroelectric multilayers

    E-Print Network [OSTI]

    Alpay, S. Pamir

    responses for which the external stimuli to induce a temperature change are magnetic and strain fields refrigeration compared to existing vapor compression/expansion technology.2 The EC response and its converse

  19. Towards the identification of the loci of adaptive 2 evolution

    E-Print Network [OSTI]

    Pardo-Diaz, Carolina; Salazar, Camilo; Jiggins, Chris D.

    2015-02-12T23:59:59.000Z

    to identify gene regions as well as genes that are responsible for its varia- tion (Stinchcombe & Hoekstra 2007; Nadeau & Jiggins 2010; Slate et al. 2010; Stapley et al. 2010; Martin & Jiggins 2013; Savolainen, Lascoux&Merila 2013;Wray 2013;Dittmar et al. 2014... ; Mackay, Stone & Ayroles 2009; Nadeau & Jiggins 2010; Stapley et al. 2010; Slate 2013) (Table 1). In sticklebacks, for example, pel- vic structures and pigmentation play adaptive roles as defen- sive structures against predation and crypsis, respectively...

  20. Modeling Cortical Plasticity Based on Adapting Lateral Interaction

    E-Print Network [OSTI]

    A neural network model called LISSOM for the cooperative self-organization of afferent and lateral connections in cortical maps is applied to modeling cortical plasticity. After self-organization, the LISSOM maps are in a dynamic equilibrium with the input, and reorganize like the cortex in response to simulated cortical lesions and intracortical microstimulation. The model predicts that adapting lateral interactions are fundamental to cortical reorganization, and suggests techniques to hasten recovery following sensory cortical surgery.

  1. Crowdsourcing affective responses for predicting media effectiveness

    E-Print Network [OSTI]

    McDuff, Daniel Jonathan

    2014-01-01T23:59:59.000Z

    Emotion is key to the effectiveness of media, whether it be in influencing memory, likability or persuasion. Stories and narratives, even if fictional, have the ability to induce a genuine emotional response. However, the ...

  2. Regulation of phosphate starvation response in Arabidopsis

    E-Print Network [OSTI]

    Thomas, Beth Elene Armstrong

    2007-04-25T23:59:59.000Z

    Biochemical Responses of Plants to Phosphate Starvation???. 3 Metabolic Adaptations to Decrease Plant Pi Requirements???. 9 Pi Starvation Regulated Gene Expression in Plants??????. 11... x LIST OF FIGURES FIGURE Page 1.1 Some known components and their relationship in the Pi starvation...

  3. Adaptive Liquid Crystal Windows

    SciTech Connect (OSTI)

    Taheri, Bahman; Bodnar, Volodymyr

    2011-12-31T23:59:59.000Z

    Energy consumption by private and commercial sectors in the U.S. has steadily grown over the last decade. The uncertainty in future availability of imported oil, on which the energy consumption relies strongly, resulted in a dramatic increase in the cost of energy. About 20% of this consumption are used to heat and cool houses and commercial buildings. To reduce dependence on the foreign oil and cut down emission of greenhouse gases, it is necessary to eliminate losses and reduce total energy consumption by buildings. To achieve this goal it is necessary to redefine the role of the conventional windows. At a minimum, windows should stop being a source for energy loss. Ideally, windows should become a source of energy, providing net gain to reduce energy used to heat and cool homes. It is possible to have a net energy gain from a window if its light transmission can be dynamically altered, ideally electronically without the need of operator assistance, providing optimal control of the solar gain that varies with season and climate in the U.S. In addition, the window must not require power from the building for operation. Resolution of this problem is a societal challenge and of national interest and will have a broad global impact. For this purpose, the year-round, allclimate window solution to provide an electronically variable solar heat gain coefficient (SHGC) with a wide dynamic range is needed. AlphaMicron, Inc. (AMI) developed and manufactured 1ft × 1ft prototype panels for the world’s first auto-adjusting Adaptive Liquid Crystal Windows (ALCWs) that can operate from sunlight without the need for external power source and demonstrate an electronically adjustable SHGC. This novel windows are based on AlphaMicron’s patented e-Tint® technology, a guesthost liquid crystal system implemented on flexible, optically clear plastic films. This technology is suitable both for OEM and aftermarket (retro-fitting) lamination to new and existing windows. Low level of power consumption by ALCWs allows for on-board power electronics for automatic matching of transmission through windows to varying climate conditions without drawing the power from the power grid. ALCWs are capable of transmitting more sunlight in winters to assist in heating and less sunlight in summers to minimize overheating. As such, they can change the window from being a source of energy loss to a source of energy gain. In addition, the scalable AMI’s roll-to-roll process, proved by making 1ft × 1ftALCW prototype panels, allows for cost-effective production of large-scale window panels along with capability to change easily their color and shape. In addition to architectural glazing in houses and commercial buildings, ALCWs can be used in other applications where control of sunlight is needed, such as green houses, used by commercial produce growers and botanical gardens, cars, aircrafts, etc.

  4. Adaptive Optics for Large Telescopes

    SciTech Connect (OSTI)

    Olivier, S

    2008-06-27T23:59:59.000Z

    The use of adaptive optics was originally conceived by astronomers seeking to correct the blurring of images made with large telescopes due to the effects of atmospheric turbulence. The basic idea is to use a device, a wave front corrector, to adjust the phase of light passing through an optical system, based on some measurement of the spatial variation of the phase transverse to the light propagation direction, using a wave front sensor. Although the original concept was intended for application to astronomical imaging, the technique can be more generally applied. For instance, adaptive optics systems have been used for several decades to correct for aberrations in high-power laser systems. At Lawrence Livermore National Laboratory (LLNL), the world's largest laser system, the National Ignition Facility, uses adaptive optics to correct for aberrations in each of the 192 beams, all of which must be precisely focused on a millimeter scale target in order to perform nuclear physics experiments.

  5. Training Adaptive Decision-Making.

    SciTech Connect (OSTI)

    Abbott, Robert G.; Forsythe, James C.

    2014-10-01T23:59:59.000Z

    Adaptive Thinking has been defined here as the capacity to recognize when a course of action that may have previously been effective is no longer effective and there is need to adjust strategy. Research was undertaken with human test subjects to identify the factors that contribute to adaptive thinking. It was discovered that those most effective in settings that call for adaptive thinking tend to possess a superior capacity to quickly and effectively generate possible courses of action, as measured using the Category Generation test. Software developed for this research has been applied to develop capabilities enabling analysts to identify crucial factors that are predictive of outcomes in fore-on-force simulation exercises.

  6. Obesity cannot be controlled through personal responsibility alone

    E-Print Network [OSTI]

    Viglas, Anastasios

    Obesity cannot be controlled through personal responsibility alone By Ben Brooks McDonald's cookies - a corporate defence strategy adapted from the tobacco and alcohol industries. By implication, obesity responsibility for obesity and diabetes would likely require highly invasive disincentives like sugar or beverage

  7. Original article Response of Pinus pinaster Ait. provenances at early

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    . pinaster in response to water shortage. These physiological adaptations complement known morphologicalOriginal article Response of Pinus pinaster Ait. provenances at early age to water supply. I. Water evolution of tissue water relations was assessed in 1-year-old seedlings of four Pinus pinaster Ait. prove

  8. Genetic shift in photoperiodic response correlated with global warming

    E-Print Network [OSTI]

    Cochran-Stafira, D. Liane

    Genetic shift in photoperiodic response correlated with global warming William E. Bradshaw observed in insects, birds, amphibians, and plants associated with global warm- ing during the latter half- tent with an adaptive evolutionary response to recent global warming. The latter half of the 20th

  9. Adaptive optics for enhanced signal in CARS A. J. Wright1

    E-Print Network [OSTI]

    Xie, Xiaoliang Sunney

    Adaptive optics for enhanced signal in CARS microscopy A. J. Wright1 , S. P. Poland1 , J. M. Girkin with coherent anti-Stokes Raman scattering (CARS) microscopy for label-free deep tissue imaging based tissue in order to enhance the CARS signal. The combined system and sample-induced aberration correction

  10. AN ADAPTIVE PHASE EQUALIZER FOR REDUCING TIMING JITTER DUE TO ACOUSTIC EFFECT

    E-Print Network [OSTI]

    Adali, Tulay

    AN ADAPTIVE PHASE EQUALIZER FOR REDUCING TIMING JITTER DUE TO ACOUSTIC EFFECT TulayAdah, Yi Cai propagating in optical fibers is the timing jitter. Acoustic effect, unlike other sources of timing jitter for the acoustically induced timing jitter (AITJ). We show that the equalizer can be trained in a "semi-blind" fashion

  11. adaptive control algorithm: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    24 25 Next Page Last Page Topic Index 1 ON AN ADAPTIVE CONTROL ALGORITHM FOR ADAPTIVE OPTICS APPLICATIONS Mathematics Websites Summary: ON AN ADAPTIVE CONTROL ALGORITHM FOR...

  12. BC Agriculture Climate Change Adaptation

    E-Print Network [OSTI]

    Pedersen, Tom

    BC Agriculture Climate Change Adaptation Risk + Opportunity Assessment Provincial Report executive summary #12;published March 2012 by the British Columbia Agriculture & Food Climate Action Initiative www.BCAgClimateAction.ca project funding provided by Agriculture and Agri-food Canada BC Ministry of Agriculture BC Ministry

  13. BC Agriculture Climate Change Adaptation

    E-Print Network [OSTI]

    Pedersen, Tom

    BC Agriculture Climate Change Adaptation Risk + Opportunity Assessment Provincial Report #12;published March 2012 by the British Columbia Agriculture & Food Climate Action Initiative www.BCAgClimateAction.ca project funding provided by Agriculture and Agri-food Canada BC Ministry of Agriculture BC Ministry

  14. Adaptive Noisy Clustering Michael CHICHIGNOUD

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    with respect to the Lebesgue measure. Since we observe a corrupted sample, a direct approach as the popular k-means is not suitable in this case. In this paper, we propose a noisy k-means minimization, which is based on the k-means an adaptive upper bound for a new selection rule, called ERC (Empirical Risk Comparison). This selection rule

  15. Hierarchical Adaptive Dynamic Power Management

    E-Print Network [OSTI]

    Chen, Yuanzhu Peter

    Hierarchical Adaptive Dynamic Power Management Zhiyuan Ren, Member, IEEE, Bruce H. Krogh, Fellow, IEEE, and Radu Marculescu, Member, IEEE Abstract--Dynamic power management aims at extending battery management strategies can lead to poor performance or unnecessary power consumption when there are wide

  16. Adaptive wiener image restoration kernel

    DOE Patents [OSTI]

    Yuan, Ding (Henderson, NV)

    2007-06-05T23:59:59.000Z

    A method and device for restoration of electro-optical image data using an adaptive Wiener filter begins with constructing imaging system Optical Transfer Function, and the Fourier Transformations of the noise and the image. A spatial representation of the imaged object is restored by spatial convolution of the image using a Wiener restoration kernel.

  17. Adaptive protection algorithm and system

    DOE Patents [OSTI]

    Hedrick, Paul (Pittsburgh, PA) [Pittsburgh, PA; Toms, Helen L. (Irwin, PA) [Irwin, PA; Miller, Roger M. (Mars, PA) [Mars, PA

    2009-04-28T23:59:59.000Z

    An adaptive protection algorithm and system for protecting electrical distribution systems traces the flow of power through a distribution system, assigns a value (or rank) to each circuit breaker in the system and then determines the appropriate trip set points based on the assigned rank.

  18. Process Control Minitoring by Stress Response

    SciTech Connect (OSTI)

    Hazen, Terry C.; Stahl, David A.

    2006-04-17T23:59:59.000Z

    Environmental contamination with a variety of pollutants hasprompted the development of effective bioremediation strategies. But howcan these processes be best monitored and controlled? One avenue underinvestigation is the development of stress response systems as tools foreffective and general process control. Although the microbial stressresponse has been the subject of intensive laboratory investigation, theenvironmental reflection of the laboratory response to specific stresseshas been little explored. However, it is only within an environmentalcontext, in which microorganisms are constantly exposed to multiplechanging environmental stresses, that there will be full understanding ofmicrobial adaptive resiliency. Knowledge of the stress response in theenvironment will facilitate the control of bioremediation and otherprocesses mediated by complex microbial communities.

  19. Adapting Your Home for More Accessible Living

    E-Print Network [OSTI]

    Harris, Janie

    2007-04-27T23:59:59.000Z

    It is important for people to live comfortably and independently in their homes. Homes can be adapted to aid people with various disabilities. This publication explains how to make such adaptations for people with vision loss, hearing loss, problems...

  20. IIR algorithms for adaptive line enhancement

    SciTech Connect (OSTI)

    David, R.A.; Stearns, S.D.; Elliott, G.R.; Etter, D.M.

    1983-01-01T23:59:59.000Z

    We introduce a simple IIR structure for the adaptive line enhancer. Two algorithms based on gradient-search techniques are presented for adapting the structure. Results from experiments which utilized real data as well as computer simulations are provided.

  1. Final Report What Will Adaptation Cost?

    E-Print Network [OSTI]

    ..................................................................................................................26 Task 3: Estimate Costs of Implementing Adaptation Strategies ....................................................................34 Task 2: Calculate the Capital and Maintenance CostsFinal Report What Will Adaptation Cost? An Economic Framework for Coastal Community Infrastructure

  2. CLIMATE VULNERABILITY AND ADAPTATION STUDY FOR

    E-Print Network [OSTI]

    CLIMATE VULNERABILITY AND ADAPTATION STUDY FOR CALIFORNIA Legal Analysis of Barriers's California Climate Change Center JULY 2012 CEC5002012019 Prepared for: California Energy Commission to that framework that would facilitate adaptation to climate change. Since such changes may be difficult

  3. Sequential optimization through adaptive design of experiments

    E-Print Network [OSTI]

    Wang, Hungjen, 1971-

    2007-01-01T23:59:59.000Z

    This thesis considers the problem of achieving better system performance through adaptive experiments. For the case of discrete design space, I propose an adaptive One-Factor-at-A-Time (OFAT) experimental design, study its ...

  4. Cellular responses to environmental DNA damage

    SciTech Connect (OSTI)

    Not Available

    1994-08-01T23:59:59.000Z

    This volume contains the proceedings of the conference entitled Cellular Responses to Environmental DNA Damage held in Banff,Alberta December 1--6, 1991. The conference addresses various aspects of DNA repair in sessions titled DNA repair; Basic Mechanisms; Lesions; Systems; Inducible Responses; Mutagenesis; Human Population Response Heterogeneity; Intragenomic DNA Repair Heterogeneity; DNA Repair Gene Cloning; Aging; Human Genetic Disease; and Carcinogenesis. Individual papers are represented as abstracts of about one page in length.

  5. Article original Adaptation digestive du lapin

    E-Print Network [OSTI]

    Boyer, Edmond

    Article original Adaptation digestive du lapin à la teneur en constituants pariétaux du régime ne diffère pas d'un régime à l'autre, du fait d'une régulation de l'énergie digestible ingérée. L le régime B. lapin / digestion / fibre / adaptation / transit Summary — Digestive adaptation

  6. Formally Analyzing Adaptive Flight Control Ashish Tiwari

    E-Print Network [OSTI]

    Tiwari, Ashish

    tiwari@csl.sri.com Abstract. We formally verify a direct model-reference adaptive control (MRAC) method adaptive flight control. The main source of our model is [8] and [1]. The high-level architectureFormally Analyzing Adaptive Flight Control Ashish Tiwari SRI International Menlo Park, CA 94025

  7. Climate Change Adaptation for Local Government

    E-Print Network [OSTI]

    Pedersen, Tom

    Climate Change Adaptation for Local Government A Resource Guide June 2011 Jenny Fraser, Adaptation to Climate Change Team, Simon Fraser University #12;Page 1 of 26 Climate Change Adaptation for Local: RESOURCES THAT SUPPORT CLIMATE CHANGE ASSESSMENT 3. Past and Future Climate Change and Its Impacts 4

  8. Anisotropic Grid Adaptation for Multiple Aerodynamic Outputs

    E-Print Network [OSTI]

    Peraire, Jaime

    Anisotropic Grid Adaptation for Multiple Aerodynamic Outputs David A. Venditti and David L Anisotropic grid­adaptive strategies are presented for viscous flow simulations in which the accurate estimation and Hessian-based anisotropic grid adaptation. Airfoil test cases are presented to demonstrate

  9. Adaptive security systems -- Combining expert systems with adaptive technologies

    SciTech Connect (OSTI)

    Argo, P.; Loveland, R.; Anderson, K. [and others

    1997-09-01T23:59:59.000Z

    The Adaptive Multisensor Integrated Security System (AMISS) uses a variety of computational intelligence techniques to reason from raw sensor data through an array of processing layers to arrive at an assessment for alarm/alert conditions based on human behavior within a secure facility. In this paper, the authors give an overview of the system and briefly describe some of the major components of the system. This system is currently under development and testing in a realistic facility setting.

  10. Adaptive differentiation of H-2- and Igh-restricted B lymphocyte in tetraparental bone marrow chimera

    SciTech Connect (OSTI)

    Yamamoto, H.; Bitoh, S.; Fujimoto, S.

    1987-01-15T23:59:59.000Z

    Immunization of BALB/c mice with MOPC-104E myeloma protein induced idiotype-specific enhancing B cells that acted on anti-dextran antibody producing B cells. The enhancing cells have the surface phenotype of B cells. With the use of several H-2 or Igh congenic mice, it was found that the cooperation among B cells was controlled by both the major histocompatibility complex (MHC) and Igh. The capability to generate enhancing B cell activity was analyzed by using tetraparental bone marrow chimeras. (C57BL/6 X BALB/c)F1 mice, for example, were lethally irradiated and were reconstituted with C57BL/6 and BALB/c bone marrow cells. Nine to 12 wk after the reconstitution, the chimeras were immunized with the myeloma protein and were tested for their enhancing B cell activity. After the removal of C57BL/6 origin cells by treatment with anti-H-2b + complement, residual cells exhibited enhancing B cell activity on BALB.B, as well as BALB/c antidextran antibody response. This indicates that the generation of H-2-restricted, idiotype-specific enhancing B cell activity differentiated adaptively so as to recognize foreign MHC as self under chimeric conditions. On the other hand, splenic B cells treated with anti-H-2d + complement did not enhance the responses of BALB/c or BALB.B. Even in a chimeric environment, the B cells of C57BL/6 origin could not obtain the ability to generate enhancing B cell activity upon immunization of the idiotype. The results described here, taken in conjunction with our previous studies, suggest that the Ig heavy chain gene(s) predominantly control the Igh restriction properties of enhancing B cells, and the capability of MHC recognition by B cells is selected under chimeric conditions.

  11. adaptive immune regulators: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Ecosystem Adaptive Management Environmental Sciences and Ecology Websites Summary: ;2 Baltic Ecosystem Adaptive Management, BEAM, r ett tvrvetenskapligt...

  12. adapter protein tsad: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Ecosystem Adaptive Management Environmental Sciences and Ecology Websites Summary: ;2 Baltic Ecosystem Adaptive Management, BEAM, r ett tvrvetenskapligt...

  13. adaptive numerical treatment: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Ecosystem Adaptive Management Environmental Sciences and Ecology Websites Summary: ;2 Baltic Ecosystem Adaptive Management, BEAM, r ett tvrvetenskapligt...

  14. adaptive antitumor immunity: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Ecosystem Adaptive Management Environmental Sciences and Ecology Websites Summary: ;2 Baltic Ecosystem Adaptive Management, BEAM, r ett tvrvetenskapligt...

  15. adaptation azole drug: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Ecosystem Adaptive Management Environmental Sciences and Ecology Websites Summary: ;2 Baltic Ecosystem Adaptive Management, BEAM, r ett tvrvetenskapligt...

  16. Adaptive Stabilization of Nonlinear Stochastic Systems

    SciTech Connect (OSTI)

    Florchinger, P. [URA CNRS No. 399, Departement de Mathematiques, UFR MIM, Universite de Metz, Ile du Saulcy, F 57045 Metz Cedex (France)

    1998-07-15T23:59:59.000Z

    The purpose of this paper is to study the problem of asymptotic stabilization in probability of nonlinear stochastic differential systems with unknown parameters. With this aim, we introduce the concept of an adaptive control Lyapunov function for stochastic systems and we use the stochastic version of Artstein's theorem to design an adaptive stabilizer. In this framework the problem of adaptive stabilization of a nonlinear stochastic system is reduced to the problem of asymptotic stabilization in probability of a modified system. The design of an adaptive control Lyapunov function is illustrated by the example of adaptively quadratically stabilizable in probability stochastic differential systems.

  17. Center for Adaptive Optics* Santa Cruz,CA

    E-Print Network [OSTI]

    Grether, Gregory

    Center for Adaptive Optics* Santa Cruz,CA The Center for Adaptive Optics (CfAO) will concentrate on astronomical and vision science applications of adaptive optics and will reach out to other adaptive optics communities to share technologies. It will develop new instruments optimized for adaptive optics. Adaptive

  18. Response Elements

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2007-07-11T23:59:59.000Z

    The Guide provides acceptable methods for meeting the requirement of DOE O 151.1C for response elements that respond or contribute to response as needed in an emergency. Cancels DOE G 151.1-1, Volume 3-1, DOE G 151.1-1, Volume 3-2, DOE G 151.1-1, Volume 3-3, DOE G 151.1-1, Volume 3-4, DOE G 151.1-1, Volume 4-1, DOE G 151.1-1, Volume 4-2, DOE G 151.1-1, Volume 4-3, DOE G 151.1-1, Volume 4-4, DOE G 151.1-1, Volume 4-5, and DOE G 151.1-1, Volume 4-6.

  19. Adapting to Climate Change and Variability in the Great Lakes-St. Lawrence Basin Great Lakes-St. Lawrence Basin Project

    E-Print Network [OSTI]

    ; this is the adaptation component. Communication of climate change information to various publicsAdapting to Climate Change and Variability in the Great Lakes-St. Lawrence Basin 52 Great Lakes in response to potential climate change and variability. When we were preparing for this talk on what we have

  20. Synthetic long peptide booster immunization in rhesus macaques primed with replication-competent NYVAC-C-KC induces a balanced CD4/CD8 T-cell and antibody response against the conserved regions of HIV-1

    E-Print Network [OSTI]

    Mooij, Petra; Koopman, Gerrit; Drijfhout, Jan Wouter; Nieuwenhuis, Ivonne G.; Beenhakker, Niels; Koestler, Josef; Bogers, Willy M.J.M.; Wagner, Ralf; Esteban, Mariano; Pantaleo, Giuseppe; Heeney, Jonathan L.; Jacobs, Bertram L.; Melief, Cornelis J.M.

    2015-02-09T23:59:59.000Z

    predominantly HIV-1 Pol-specific. The animals showed a balanced polyfunctional CD4 and CD8 T-cell response and high Ab titers. Powered by Editorial Manager® and ProduXion Manager® from Aries Systems Corporation JGV Papers in Press. Published February 9, 2015... , ? CSIC, ? Madrid, ? Spain; ?15 e Division ? of ? Immunology ? and ? Allergy, ? Centre ? Hospitalier ? Universitaire ? Vaudois, ?16 Lausanne, ? Switzerland; ? f Swiss ? Vaccine ? Research ? Institute, ? Lausanne, ? Switzerland; ?17 g Department ?of...

  1. Adaptive management: a paradigm for remediation of public facilities

    SciTech Connect (OSTI)

    Janecky, David R [Los Alamos National Laboratory; Whicker, Jeffrey J [Los Alamos National Laboratory; Doerr, Ted B [NON LANL

    2009-01-01T23:59:59.000Z

    Public facility restoration planning traditionally focused on response to natural disasters and hazardous materials accidental releases. These plans now need to integrate response to terrorist actions. Therefore, plans must address a wide range of potential vulnerabilities. Similar types of broad remediation planning are needed for restoration of waste and hazardous material handling areas and facilities. There are strong similarities in damage results and remediation activities between unintentional and terrorist actions; however, the uncertainties associated with terrorist actions result in a re-evaluation of approaches to planning. Restoration of public facilities following a release of a hazardous material is inherently far more complex than in confined industrial settings and has many unique technical, economic, social, and political challenges. Therefore, they arguably involve a superset of drivers, concerns and public agencies compared to other restoration efforts. This superset of conditions increases complexity of interactions, reduces our knowledge of the initial conditions, and even condenses the timeline for restoration response. Therefore, evaluations of alternative restoration management approaches developed for responding to terrorist actions provide useful knowledge for large, complex waste management projects. Whereas present planning documents have substantial linearity in their organization, the 'adaptive management' paradigm provides a constructive parallel operations paradigm for restoration of facilities that anticipates and plans for uncertainty, multiple/simUltaneous public agency actions, and stakeholder participation. Adaptive management grew out of the need to manage and restore natural resources in highly complex and changing environments with limited knowledge about causal relationships and responses to restoration actions. Similarities between natural resource management and restoration of a facility and surrounding area(s) after a disruptive event suggest numerous advantages over preset linearly-structured plans by incorporating the flexibility and overlap of processes inherent in effective facility restoration. We discuss three restoration case studies (e.g., the Hart Senate Office Building anthrax restoration, Rocky Flats actinide remediation, and hurricane destruction restoration), that implement aspects of adaptive management but not a formal approach. We propose that more formal adoption of adaptive management principles could be a basis for more flexible standards to improve site-specific remediation plans under conditions of high uncertainty.

  2. Submitted to Vehicle System Dynamics An Adaptive Lateral Preview Driver Model

    E-Print Network [OSTI]

    Peng, Huei

    of the vehicle. The proposed driver model is developed using the adaptive predictive control (APC) framework inspires our interest in understanding human steering actions and the development of a driver model on the response of the vehicle. These tests can be performed with a steering and speed control robot, and thus can

  3. Performance of Adaptive Query Processing in the Mariposa Distributed Database Management System

    E-Print Network [OSTI]

    California at Irvine, University of

    present performance results which show that in multi-user situations, when response time is used assigns a price to perform a service and may adjust its prices as it sees fit. In designing Mariposa such as the effect of supply and demand on prices. We investigate the benefits of adaptive distributed query

  4. Adaptation of Log Domain Second Order Filters Implemented by Floating Gate MOSFETs

    E-Print Network [OSTI]

    Maryland at College Park, University of

    Amplifier (AFGA) and its use in bandpass filter structures with very low frequency response capability based on the first order low-pass filter design. Section II develops robust learning rules for adapting the opportunity to reject noise and improve signal quality dynamically in a variety of complex and demanding

  5. Adaptive Jitter Control for UPnP M-Search Kevin Mills and Christopher Dabrowski

    E-Print Network [OSTI]

    Adaptive Jitter Control for UPnP M-Search Kevin Mills and Christopher Dabrowski Information service-discovery system, UPnP, permits clients to include a jitter bound in multicast (M-Search) queries. Qualifying devices use the jitter bound to randomize timing of their responses. Initially, clients lack

  6. Climate Change Adaptation New Perspectives for Natural Resource Management and Conservation1

    E-Print Network [OSTI]

    Mazzotti, Frank

    Climate Change Adaptation New Perspectives for Natural Resource Management and Conservation1 Institute of Food and Agricultural Sciences February 2012 A Changing Climate for Conservation Climate change species of plants and animals are already shifting their distributions in response to climate change

  7. Rights-based evaluation of government responses to a given 'natural' disaster : Katrina as case study

    E-Print Network [OSTI]

    Haeffner, Melissa (Melissa Ann)

    2010-01-01T23:59:59.000Z

    Disaster impacts human mobility and a rights-based approach to disaster response is needed to protect the human rights of those who seek migration as an adaptation strategy. This paper deals with returning to a place after ...

  8. Dscam gene expression in invertebrate immunity : alternative splicing in response to diverse pathogens 

    E-Print Network [OSTI]

    Smith, Paul Hugh

    2012-11-30T23:59:59.000Z

    Invertebrates show enhanced immunity and even specific primed immunity in response to repeat infections, analogous to vertebrate adaptive immunity. Little is known of the mechanism for this phenomenon, or which molecules ...

  9. Using the Heat-Shock Response To Discover Anticancer Compounds that Target Protein Homeostasis

    E-Print Network [OSTI]

    Santagata, Sandro

    Unlike normal tissues, cancers experience profound alterations in protein homeostasis. Powerful innate adaptive mechanisms, especially the transcriptional response regulated by Heat Shock Factor 1 (HSF1), are activated in ...

  10. Issues in adaptive mesh refinement

    SciTech Connect (OSTI)

    Dai, William Wenlong [Los Alamos National Laboratory

    2009-01-01T23:59:59.000Z

    In this paper, we present an approach for a patch-based adaptive mesh refinement (AMR) for multi-physics simulations. The approach consists of clustering, symmetry preserving, mesh continuity, flux correction, communications, and management of patches. Among the special features of this patch-based AMR are symmetry preserving, efficiency of refinement, special implementation offlux correction, and patch management in parallel computing environments. Here, higher efficiency of refinement means less unnecessarily refined cells for a given set of cells to be refined. To demonstrate the capability of the AMR framework, hydrodynamics simulations with many levels of refinement are shown in both two- and three-dimensions.

  11. Demand Response and Open Automated Demand Response

    E-Print Network [OSTI]

    LBNL-3047E Demand Response and Open Automated Demand Response Opportunities for Data Centers G described in this report was coordinated by the Demand Response Research Center and funded by the California. Demand Response and Open Automated Demand Response Opportunities for Data Centers. California Energy

  12. Chronic cadmium exposure in vitro induces cancer cell characteristics in human lung cells

    SciTech Connect (OSTI)

    Person, Rachel J.; Tokar, Erik J.; Xu, Yuanyuan; Orihuela, Ruben; Ngalame, Ntube N. Olive; Waalkes, Michael P., E-mail: waalkes@niehs.nih.gov

    2013-12-01T23:59:59.000Z

    Cadmium is a known human lung carcinogen. Here, we attempt to develop an in vitro model of cadmium-induced human lung carcinogenesis by chronically exposing the peripheral lung epithelia cell line, HPL-1D, to a low level of cadmium. Cells were chronically exposed to 5 ?M cadmium, a noncytotoxic level, and monitored for acquired cancer characteristics. By 20 weeks of continuous cadmium exposure, these chronic cadmium treated lung (CCT-LC) cells showed marked increases in secreted MMP-2 activity (3.5-fold), invasion (3.4-fold), and colony formation in soft agar (2-fold). CCT-LC cells were hyperproliferative, grew well in serum-free media, and overexpressed cyclin D1. The CCT-LC cells also showed decreased expression of the tumor suppressor genes p16 and SLC38A3 at the protein levels. Also consistent with an acquired cancer cell phenotype, CCT-LC cells showed increased expression of the oncoproteins K-RAS and N-RAS as well as the epithelial-to-mesenchymal transition marker protein Vimentin. Metallothionein (MT) expression is increased by cadmium, and is typically overexpressed in human lung cancers. The major MT isoforms, MT-1A and MT-2A were elevated in CCT-LC cells. Oxidant adaptive response genes HO-1 and HIF-1A were also activated in CCT-LC cells. Expression of the metal transport genes ZNT-1, ZNT-5, and ZIP-8 increased in CCT-LC cells culminating in reduced cadmium accumulation, suggesting adaptation to the metal. Overall, these data suggest that exposure of human lung epithelial cells to cadmium causes acquisition of cancer cell characteristics. Furthermore, transformation occurs despite the cell's ability to adapt to chronic cadmium exposure. - Highlights: • Chronic cadmium exposure induces cancer cell characteristics in human lung cells. • This provides an in vitro model of cadmium-induced human lung cell transformation. • This occurred with general and lung specific changes typical for cancer cells. • These findings add insight to the relationship between cadmium and lung cancer.

  13. INPUT CONSTRAINED ADAPTIVE TRACKING WITH APPLICATIONS TO

    E-Print Network [OSTI]

    Knobloch,Jürgen

    as models in several industries including continuous polymerization reactors, distillation columns tracking ac- curacy, quantified by > 0 set by the designer, is ensured. The adaptive control strategy does

  14. Training for Climate Adaptation in Conservation

    Broader source: Energy.gov [DOE]

    The Wildlife Conservation Society and the Northern Institute of Applied Climate Science are hosting this two-day training for climate adaptation.

  15. Protein Structure Suggests Role as Molecular Adapter

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Protein Structure Suggests Role as Molecular Adapter Print To split and copy DNA during replication, all cellular organisms use a multicomponent molecular machine known as the...

  16. Optimization Online - An Adaptive Unified Differential Evolution ...

    E-Print Network [OSTI]

    Ji Qiang

    2015-02-19T23:59:59.000Z

    Feb 19, 2015 ... Abstract: In this paper, we propose a new adaptive unified differential evolution algorithm for single-objective global optimization. Instead of the ...

  17. GLOBAL AND ADAPTIVE SCALING IN A SEPARABLE ...

    E-Print Network [OSTI]

    2007-10-19T23:59:59.000Z

    programs confirm that Adaptive Global Scaling subsumes former scaling ...... Then, the compact convex set B of symmetric matrices eigeinvalues of which.

  18. Mainstreaming Climate Change Adaptation into Development Planning...

    Open Energy Info (EERE)

    Practitioners Jump to: navigation, search Tool Summary LAUNCH TOOL Name: Mainstreaming Climate Change Adaptation into Development Planning: A Guide for Practitioners Agency...

  19. Assessing Climate Change Impacts, Vulnerability and Adaptation...

    Open Energy Info (EERE)

    The Case of Pantabangan-Carranglan Watershed Jump to: navigation, search Name Assessing Climate Change Impacts, Vulnerability and Adaptation: The Case of Pantabangan-Carranglan...

  20. Direct Measurement of the Electron Density of Extended Femtosecond Laser Pulse-Induced Filaments

    SciTech Connect (OSTI)

    Chen, Y.-H.; Varma, S.; Antonsen, T. M.; Milchberg, H. M. [Institute for Research in Electronics and Applied Physics, University of Maryland, College Park, Maryland 20742 (United States)

    2010-11-19T23:59:59.000Z

    We present direct time- and space-resolved measurements of the electron density of femtosecond laser pulse-induced plasma filaments. The dominant nonlinearity responsible for extended atmospheric filaments is shown to be field-induced rotation of air molecules.

  1. Transcriptome and Proteome Dynamics of the Cellular Response of Shewanella oneidensis to Chromium Stress

    SciTech Connect (OSTI)

    Thompson, D.K.

    2005-04-18T23:59:59.000Z

    The overall goal of this DOE NABIR project is to characterize the molecular basis and regulation of hexavalent chromium [Cr(VI)] stress response and reduction by Shewanella oneidensis strain MR-1. Temporal genomic profiling and mass spectrometry-based proteomic analysis were employed to characterize the dynamic molecular response of S. oneidensis MR-1 to both acute and chronic Cr(VI) exposure. The acute stress response of aerobic, mid-exponential phase cells shocked to a final concentration of 1 mM potassium chromate (K2CrO4) was examined at post-exposure time intervals of 5, 30, 60, and 90 min relative to untreated cells. The transcriptome of mid-exponential cultures was also analyzed 30 min after shock doses of 0.3, 0.5, or 1 mM K{sub 2}CrO{sub 4}. The tonB1-exbB1-exbD1 genes comprising the TonB1 iron transport system were some of the most highly induced coding sequences (CDSs) after 90 min (up to {approx}240 fold), followed by other genes involved in heme transport, sulfate transport, and sulfur assimilation pathways. In addition, transcript levels for CDSs with annotated functions in DNA repair (dinP, recX, recA, recN) and detoxification processes (so3585, so3586) were substantially increased in Cr(VI)-exposed cells compared to untreated cells. By contrast, genes predicted to encode hydrogenases (HydA, HydB), oxidoreductases (SO0902-03-04, SO1911), iron-sulfur cluster binding proteins (SO4404), decaheme cytochrome c proteins (MtrA, OmcA, OmcB), and a number of LysR or TetR family transcriptional regulators were some of the most highly repressed CDSs following the 90-min shock period. Transcriptome profiles generated from MR-1 cells adapted to 0.3 mM Cr(VI) differed significantly from those characterizing cells exposed to acute Cr(VI) stress without adaptation. Parallel proteomic characterization of soluble protein and membrane protein fractions extracted from Cr(VI)-shocked and Cr(VI)-adapted MR-1 cells was performed using multidimensional HPLC-ESI-MS/MS (both LCQ and LTQ instruments used). With LTQ, we were able to substantially increase proteome coverage by at least two-fold compared to LCQ analysis. These studies provide important insights into cellular chromium tolerance. Future research will focus on the structural and regulatory genes implicated in Cr(VI) reduction and detoxification.

  2. adaptive-influence-matrix adaptive optics: Topics by E-print...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    adaptive-influence-matrix adaptive optics First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Adaptive...

  3. Optimized multifrequency light collection by adaptive self-ordering of scatterers in optical resonators

    E-Print Network [OSTI]

    Torggler, Valentin

    2014-01-01T23:59:59.000Z

    Mobile light scatterers in a high-Q optical cavity transversely illuminated by laser light close to a cavity resonance form ordered patterns, which maximize light scattering into the cavity and induce optical self-trapping. We show that a generalized form of such crystallization dynamics appears in multicolored pump fields with several cavity modes. Here the particles arrange in spatial patterns maximizing total light collection into the resonator. For changing input frequencies and strengths the particles dynamically adapt to the current illumination. Interestingly the system keeps some memory on past configurations, so that a later renewed application of the same pattern exhibits faster adaptation towards optimal collective scattering. In a noisy environment particles explore larger regions of configuration space spending most of the time close to optimum scattering configurations. This adaptive self-ordering dynamics should be implementable in a wide range of systems ranging from cold atoms in multimode ca...

  4. anti-malaria humoral responses: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    is believed to share limited Paris-Sud XI, Universit de 7 Isocitrate Dehydrogenase of Helicobacter pylori Potentially Induces Humoral Immune Response in Subjects with Peptic...

  5. Rapid Evolution of Coral Proteins Responsible for Interaction with the Environment

    E-Print Network [OSTI]

    Voolstra, Christian R.

    2011-01-01T23:59:59.000Z

    AM (2010) Development and heat stress-induced transcriptomicTranscriptomic responses to heat stress and bleaching in thefaveolata) during heat stress. Mar Biotechnol (NY) 2: 533–

  6. Response of a tundra ecosystem to elevated atmospheric carbon dioxide and CO{sub 2}-induced climate change. Post-field season work plan, September 1, 1994--November 30, 1994

    SciTech Connect (OSTI)

    NONE

    1994-12-31T23:59:59.000Z

    The preliminary data from the temperature and water table manipulations indicated that net CO{sub 2} flux of both tussock and wet sedge tundra ecosystems is sensitive to changes in water table depth and soil temperature. The preliminary results from the patch, landscape, and regional flux measurements indicate that there are large deficiencies in our current ability to extrapolate from patch and landscape levels to the region. During fall 1994, our primary goals are to: (1) Analyze a full season of net CO{sub 2} flux from the in situ manipulations, and determine the effects of water table depth and elevated temperature on the C balance of arctic ecosystems. Once this task is complete, the data will be published in a form that discusses the importance of these environmental controls, and their relevance to future CO{sub 2}-induced climate change. (2) Analyze tower- and aircraft-based eddy correlation flux data, and develop methods to reduce the time required to analyze these data. (3) Determine the importance of environmental controls of the exchange of CO{sub 2} at each spatial scale, and to develop the necessary routines that will permit the scaling of fine-scale flux data to landscape and regional scales. (4) Prepare manuscripts for publication on net CO{sub 2} flux data for each spatial scale, latitudinal flux pattern, and on methods and considerations for scaling from point measurements to the landscape and regional scale.

  7. Downhole tool adapted for telemetry

    DOE Patents [OSTI]

    Hall, David R. (Provo, UT); Fox, Joe (Provo, UT)

    2010-12-14T23:59:59.000Z

    A cycleable downhole tool such as a Jar, a hydraulic hammer, and a shock absorber adapted for telemetry. This invention applies to other tools where the active components of the tool are displaced when the tool is rotationally or translationally cycled. The invention consists of inductive or contact transmission rings that are connected by an extensible conductor. The extensible conductor permits the transmission of the signal before, after, and during the cycling of the tool. The signal may be continuous or intermittent during cycling. The invention also applies to downhole tools that do not cycle, but in operation are under such stress that an extensible conductor is beneficial. The extensible conductor may also consist of an extensible portion and a fixed portion. The extensible conductor also features clamps that maintain the conductor under stresses greater than that seen by the tool, and seals that are capable of protecting against downhole pressure and contamination.

  8. An adaptive radiation model for the origin of new gene functions

    E-Print Network [OSTI]

    Francino, M. Pilar

    2005-01-01T23:59:59.000Z

    An adaptive radiation model for the origin of new genePreadaptation Adaptive radiation Competition among closefor a specific niche Adaptive radiation model Adaptive gene

  9. E-Print Network 3.0 - adaptive systems theory Sample Search Results

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    systems theory Page: << < 1 2 3 4 5 > >> 1 From Adaptive Hypermedia to the Adaptive Web Systems Summary: 1 From Adaptive Hypermedia to the Adaptive Web Systems Peter...

  10. ORIGINAL ARTICLE Mitigation needs adaptation: Tropical forestry

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    ORIGINAL ARTICLE Mitigation needs adaptation: Tropical forestry and climate change Manuel R adapt to this change. This paper discusses how tropical forestry practices can contribute to maintaining Forestry Research, P.O. Box 6596 JKPWB, Jakarta 10065, Indonesia e-mail: m.guariguata@cgiar.org J. P

  11. OPTIMAL CONTROL WITH ADAPTIVE INTERNAL DYNAMICS MODELS

    E-Print Network [OSTI]

    Vijayakumar, Sethu

    . The optimal feedback control law for systems with non-linear dynamics and non-quadratic costs can be foundOPTIMAL CONTROL WITH ADAPTIVE INTERNAL DYNAMICS MODELS Djordje Mitrovic, Stefan Klanke, and Sethu, optimal control, adaptive control, robot simulation Abstract: Optimal feedback control has been proposed

  12. Adaptive Web Sites: Automatically Synthesizing Web Pages

    E-Print Network [OSTI]

    Etzioni, Oren

    Adaptive Web Sites: Automatically Synthesizing Web Pages Mike Perkowitz Oren Etzioni Department interfaces Abstract The creation of a complex web site is a thorny problem in user interface design. In IJCAI '97, we challenged the AI community to address this problem by creating adaptive web sites: sites

  13. General Adaptive Replacement Policies Yannis Smaragdakis

    E-Print Network [OSTI]

    Smaragdakis, Yannis

    General Adaptive Replacement Policies Yannis Smaragdakis College of Computing Georgia Institute of Technology yannis@cc.gatech.edu ABSTRACT We propose a general scheme for creating adaptive replace- ment any two existing replacement policies so that the resulting policy provably can never perform worse

  14. ADAPTIVE MULTIMEDIA TRANSMISSION OVER THE INTERNET

    E-Print Network [OSTI]

    Bouras, Christos

    Chapter 20 ADAPTIVE MULTIMEDIA TRANSMISSION OVER THE INTERNET CHRISTOS BOURAS and APOSTOLOS GKAMAS that are available to multimedia applications can be modified very quickly. Multimedia applications must have to multimedia applications, we can use techniques both at the network and application layers. Adaptive

  15. Adaptive Communication Agent for Group Communication activities

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    , limited energy resources), system execute adaptive mechanisms by monitoring the data flow. Also, the actor-wide collaborative environment, managing the adaptive communication is a challenging task. It implies the monitoring and executed without manual intervention. This research is applied to a Crisis Management System (CMS) within

  16. Enabling Informed Adaptation of Reformed Instructional Materials

    E-Print Network [OSTI]

    Elby, Andy

    Enabling Informed Adaptation of Reformed Instructional Materials Rachel E. Scherr and Andrew Elby 20742 USA Abstract. Instructors inevitably need to adapt even the best reform materials to suit instructors, and video clips of students working on the materials. Our materials thus facilitate their own

  17. Adaptive Filtering of Multilingual Document Streams

    E-Print Network [OSTI]

    Oard, Doug

    the volume of new documents that must be examined by the user to manageable levels. This paper presents three techniques for extending adaptive monolingual text ltering techniques to manage multilingual document streamsAdaptive Filtering of Multilingual Document Streams Douglas W. Oard College of Library

  18. DAMS: Distributed Adaptive Metaheuristic Selection Bilel Derbel

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    DAMS: Distributed Adaptive Metaheuristic Selection Bilel Derbel Université Lille 1 LIFL ­ CNRS Metaheuristic Selection (DAMS) frame- work. DAMS is dedicated to adaptive optimization in distributed environments. Given a set of metaheuristics, the goal of DAMS is to coordinate their local execution

  19. A fuzzy-tuned adaptive Kalman filter 

    E-Print Network [OSTI]

    Painter, John H.; Young Hwan Lho

    1993-12-01T23:59:59.000Z

    In this paper, fuzzy processing is applied to the adaptive Kalman filter. The filter gain coefficients are adapted over a 50 dB range of unknown signal/noise dynamics, using fuzzy membership functions. Specific simulation results are shown for a...

  20. Outreach and Adaptive Strategies for Climate Change

    E-Print Network [OSTI]

    Outreach and Adaptive Strategies for Climate Change: The Role of NOAA Sea Grant Extension years and generations about how to adapt to a changing climate. Effective preparation for possible effects of climate change includes engagement of resource managers, planners, public works officials

  1. A fuzzy-tuned adaptive Kalman filter

    E-Print Network [OSTI]

    Painter, John H.; Young Hwan Lho

    1993-12-01T23:59:59.000Z

    In this paper, fuzzy processing is applied to the adaptive Kalman filter. The filter gain coefficients are adapted over a 50 dB range of unknown signal/noise dynamics, using fuzzy membership functions. Specific simulation results are shown for a...

  2. A Garch-based adaptive playout delay algorithm for VoIP Ying Zhang a,*, Damien Fay b

    E-Print Network [OSTI]

    Haddadi, Hamed

    A Garch-based adaptive playout delay algorithm for VoIP Ying Zhang a,*, Damien Fay b , Liam Garch Playout delay Time series forecasting VoIP a b s t r a c t Network delay, packet loss and network a trade-off between the buffer-induced delay and any additional packet loss rate. In this paper, a Garch

  3. Quantum gravitational optics: the induced phase

    E-Print Network [OSTI]

    N. Ahmadi; M. Nouri-Zonoz

    2007-03-26T23:59:59.000Z

    The geometrical approximation of the extended Maxwell equation in curved spacetime incorporating interactions induced by the vacuum polarization effects is considered. Taking into account these QED interactions and employing the analogy between eikonal equation in geometrical optics and Hamilton-Jacobi equation for the particle motion, we study the phase structure of the modified theory. There is a complicated, local induced phase which is believed to be responsible for the modification of the classical picture of light ray. The main features of QGO could be obtained through the study of this induced phase. We discuss initial principles in conventional and modified geometrical optics and compare the results.

  4. Side slope design based on human tolerance to vehicle response

    E-Print Network [OSTI]

    Weaver, Graeme Douglas

    1970-01-01T23:59:59.000Z

    an investigation of simulated vehicle response to the traversal of roadside terrain features. A Texas Transportation Institute adaptation of the CALSVA model was utilized to quantify the relative lateral, longitudinal, and vertical acceleration levels generated... by traversal of roadside cross-sections commonly employed in highway design. STUDY -SOCEDURS The principal aim of this research was to investigate the vehicle dynamic response during traversal of various roadside terrain featuzes to provide a basis...

  5. Probing young massive clusters with laser guide star adaptive optics

    E-Print Network [OSTI]

    McCrady, Nate

    2009-01-01T23:59:59.000Z

    laser guide star adaptive optics Nate McCrady Received: 10laser guide star adaptive optics (LGS/AO) on the 10 m Keckof 4 Mpc. Our adaptive optics work is motivated by three

  6. Enhanced Jahn-Teller response induced by low-dose 10?MeV I{sup +} irradiation of La{sub 0.7}Ca{sub 0.3}MnO{sub 3??} films

    SciTech Connect (OSTI)

    Harris, V. G., E-mail: v.harris@neu.edu; Chen, Y. [Department of Electrical and Computer Engineering, Northeastern University, Boston, Massachusetts 02115 (United States); Byers, J. M.; Stroud, R. M.; Osofsky, M. S.; Knies, D.; Grabowski, K. S. [U.S. Naval Research Laboratory, Code 6360, Washington, DC 20375 (United States); Browning, V. M.; Fuller-Mora, W. W. [U.S. Naval Research Laboratory, Code 6340, Washington, DC 20375 (United States); Kim, J. [Neocera, LLC, 10000 Virginia Manor Road, Beltsville, Maryland 20705 (United States)

    2014-05-26T23:59:59.000Z

    The structural response of pulsed laser deposited La{sub 0.7}Ca{sub 0.3}Mn0{sub 3??} films to low-level 10?MeV I{sup +} irradiation is correlated with magnetic and electronic properties. A series of annealed pulsed laser deposited films were subjected to ion irradiation at doses of 0.5–2.0 × 10{sup 13} 10?MeV iodine ions/cm{sup 2}. X-ray diffraction measurements show no measurable increase in the full width at half maximum values of major reflections before and after irradiation. Extended x-ray absorption fine structure analyses (EXAFS), employing both a model independent fitting using expanded cumulants as well as a nonlinear least squares multiple scattering model based on FEFF generated theoretical EXAFS data, were employed to measure local properties relative to the Mn ions. Increasing irradiation doses lead to an unambiguous evolution of MnO{sub 6} octahedra from highly symmetric (i.e., undistorted) to a clear bimodal structure in which the MnO{sub 6} octahedra are measured to undergo a c-axis stretching bearing resemblance to a Jahn-Teller distortion. Concomitantly, the metal to insulator transition temperature decreases more than 270?K and the magnetoresistance increases from 10{sup 2}% to 10{sup 6}%.

  7. Oxidative stress suppression by luteolin-induced heme oxygenase-1 expression

    SciTech Connect (OSTI)

    Sun, Gui-bo; Sun, Xiao; Wang, Min [Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100193 (China)] [Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100193 (China); Ye, Jing-xue [Jilin Agricultural University, No.2888, Xincheng Street, Changchun, 130021, Jilin (China)] [Jilin Agricultural University, No.2888, Xincheng Street, Changchun, 130021, Jilin (China); Si, Jian-yong [Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100193 (China)] [Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100193 (China); Xu, Hui-bo [Academy of Chinese Medical Sciences of Jilin Province, Gongnongda road 1745, Changchun, 130021, Jiblin (China)] [Academy of Chinese Medical Sciences of Jilin Province, Gongnongda road 1745, Changchun, 130021, Jiblin (China); Meng, Xiang-bao; Qin, Meng; Sun, Jing [Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100193 (China)] [Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100193 (China); Wang, Hong-wei, E-mail: hwang@nju.edu.cn [Center for Translational Medicine and Jiangsu Key Laboratory of Molecular Medicine, Medical School of Nanjing University, Nanjing 210093 (China)] [Center for Translational Medicine and Jiangsu Key Laboratory of Molecular Medicine, Medical School of Nanjing University, Nanjing 210093 (China); Sun, Xiao-bo, E-mail: sunsubmit@163.com [Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100193 (China)] [Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100193 (China)

    2012-12-01T23:59:59.000Z

    Luteolin, a flavonoid that exhibits antioxidative properties, exerts myocardial protection effects. However, the underlying molecular mechanisms are not yet fully understood. To investigate the effects of luteolin on myocardial injury protection and its possible mechanisms, a myocardial injury model was established with intragastric administration of 4 mg/kg isoproterenol (ISO) to male Sprague–Dawley rats (200–220 g) daily for 2 days. We found that pretreatment of luteolin (160, 80 and 40 mg/kg, i.g., respectively) daily for 15 days can prevent ISO-induced myocardial damage, including decrease of serum cardiac enzymes, improvement electrocardiography and heart vacuolation. Luteolin also improved the free radical scavenging and antioxidant potential, suggesting one possible mechanism of luteolin-induced cardio-protection is mediated by blocking the oxidative stress. To clarify the mechanisms, we performed the in vitro study by hydrogen peroxide (H{sub 2}O{sub 2})-induced cytotoxicty model in H9c2 cells. We found that luteolin pretreatment prevented apoptosis, increased the expression of heme oxygenase-1 (HO-1), and enhanced the binding of Nrf2 to the antioxidant response element, providing an adaptive survival response against H{sub 2}O{sub 2}-derived oxidative cytotoxicity. The addition of Znpp, a selective HO-1 competitive inhibitor, reduced the cytoprotective ability of luteolin, indicating the vital role of HO-1 on these effects. Luteolin also activated Akt and ERK, whereas the addition of LY294002 and U0126, the pharmacologic inhibitors of PI3K and ERK, attenuated luteolin-induced HO-1 expression and cytoprotective effect. Taken together, the above findings suggest that luteolin protects against myocardial injury and enhances cellular antioxidant defense capacity through the activation of Akt and ERK signal pathways that leads to Nrf2 activation, and subsequently HO-1 induction. -- Highlights: ? Luteolin prevents isoproterenol-induced myocardial damage. ? Luteolin enhances cellular antioxidant defense capacity. ? Luteolin increases the expression of heme oxygenase-1 protein levels. ? Luteolin activates Akt and ERK signal pathways.

  8. Low Dose IR Creates an Oncogenic Microenvironment by Inducing Premature

    SciTech Connect (OSTI)

    Yuan, Zhi-Min [Harvard School of Public Health

    2013-04-28T23:59:59.000Z

    Introduction Much of the work addressing ionizing radiation-induced cellular response has been carried out mainly with the traditional cell culture technique involving only one cell type, how cellular response to IR is influenced by the tissue microenvironment remains elusive. By use of a three-dimensional (3D) co-culture system to model critical interactions of different cell types with their neighbors and with their environment, we recently showed that low-dose IR-induced extracellular signaling via the tissue environment affects profoundly cellular responses. This proposal aims at determining the response of mammary epithelial cells in a tissue-like setting.

  9. 7th International Workshop on Microbeam Probes of Cellular Radiation Response

    SciTech Connect (OSTI)

    Brenner, David J.

    2009-07-21T23:59:59.000Z

    The extended abstracts that follow present a summary of the Proceedings of the 7th International Workshop: Microbeam Probes of Cellular Radiation Response, held at Columbia University’s Kellogg Center in New York City on March 15–17, 2006. These International Workshops on Microbeam Probes of Cellular Radiation Response have been held regularly since 1993 (1–5). Since the first workshop, there has been a rapid growth (see Fig. 1) in the number of centers developing microbeams for radiobiological research, and worldwide there are currently about 30 microbeams in operation or under development. Single-cell/single-particle microbeam systems can deliver beams of different ionizing radiations with a spatial resolution of a few micrometers down to a few tenths of a micrometer. Microbeams can be used to addressquestions relating to the effects of low doses of radiation (a single radiation track traversing a cell or group of cells), to probe subcellular targets (e.g. nucleus or cytoplasm), and to address questions regarding the propagation of information about DNA damage (for example, the radiation-induced bystander effect). Much of the recent research using microbeams has been to study low-dose effects and ‘‘non-targeted’’ responses such as bystander effects, genomic instability and adaptive responses. This Workshop provided a forum to assess the current state of microbeam technology and current biological applications and to discuss future directions for development, both technological and biological. Over 100 participants reviewed the current state of microbeam research worldwide and reported on new technological developments in the fields of both physics and biology.

  10. An adaptive mesh refinement technique for dynamics of solids

    E-Print Network [OSTI]

    Trivedi, Abhishek

    2007-01-01T23:59:59.000Z

    adaptations; right: cut-off grid with a solution contour.adaptations; right: cut-off grid with a solution contour.

  11. adaptive signal detection: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    8 INTERNATIONAL JOURNAL OF ADAPTIVE CONTROL AND SIGNAL PROCESSING Int. J. Adapt. Control Signal Process. (in press) Engineering Websites Summary: predictive control 1....

  12. adaptive signal processing: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    3 INTERNATIONAL JOURNAL OF ADAPTIVE CONTROL AND SIGNAL PROCESSING Int. J. Adapt. Control Signal Process. (in press) Engineering Websites Summary: predictive control 1....

  13. adaptive information processing: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    52 INTERNATIONAL JOURNAL OF ADAPTIVE CONTROL AND SIGNAL PROCESSING Int. J. Adapt. Control Signal Process. (in press) Engineering Websites Summary: predictive control 1....

  14. adapted damage control: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    40 INTERNATIONAL JOURNAL OF ADAPTIVE CONTROL AND SIGNAL PROCESSING Int. J. Adapt. Control Signal Process. (in press) Engineering Websites Summary: predictive control 1....

  15. adaptive control: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    30 INTERNATIONAL JOURNAL OF ADAPTIVE CONTROL AND SIGNAL PROCESSING Int. J. Adapt. Control Signal Process. (in press) Engineering Websites Summary: predictive control 1....

  16. adaptive predictive control: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    applied to analyze the transient Antsaklis, Panos 44 ADAPTIVE ROBUST TRACKING CONTROL OF PRESSURE Engineering Websites Summary: 1---- 1 ADAPTIVE ROBUST TRACKING CONTROL OF...

  17. active adaptive management: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    begun to embrace the concept adaptive management as an alternative to traditional natural resource planning and management models. Adaptive management may provide BLM managers ......

  18. adaptive management department: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    begun to embrace the concept adaptive management as an alternative to traditional natural resource planning and management models. Adaptive management may provide BLM managers ......

  19. National Adaptation Forum Webinar Series: Out of Town, Not Out...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Adaptation Forum Webinar Series: Out of Town, Not Out of Trouble: Small Agriculture and Indigenous Communities National Adaptation Forum Webinar Series: Out of Town, Not Out of...

  20. Farming in a Changing Climate: Agricultural Adaptation in Canada

    E-Print Network [OSTI]

    Jain, Varinder

    2010-01-01T23:59:59.000Z

    Agricultural Adaptation in Canada Ellen Wall, Barry Smit,Agricultural Adaptation in Canada. Vancouver, BC: Universitythe agri-food sector in Canada, the insights provided are so

  1. Enabling High Efficiency Low Temperature Combustion by Adaptive...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Low Temperature Combustion by Adaptive In-Situ Jet Cooling Enabling High Efficiency Low Temperature Combustion by Adaptive In-Situ Jet Cooling A new approach, called...

  2. adaptive optimal control: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    result. In this procedure it is essential Campi, Marco 3 Adaptive Control System Optimization for Vibration Control of Flexible Structures Engineering Websites Summary: Adaptive...

  3. adaptive particle swarm: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Last Page Topic Index 1 An Adaptive Learning Particle Swarm Optimizer for Function Optimization Computer Technologies and Information Sciences Websites Summary: An Adaptive...

  4. adaptive intrusion detection: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Last Page Topic Index 1 Adaptive Model Generation for Intrusion Detection Systems Computer Technologies and Information Sciences Websites Summary: Adaptive Model Generation for...

  5. Seismic Technology Adapted to Analyzing and Developing Geothermal...

    Broader source: Energy.gov (indexed) [DOE]

    Seismic Technology Adapted to Analyzing and Developing Geothermal Systems Below Surface-Exposed High-Velocity Rocks Seismic Technology Adapted to Analyzing and Developing...

  6. Implementing Adaptive Performance Management in Server Applications

    SciTech Connect (OSTI)

    Liu, Yan; Gorton, Ian

    2007-06-11T23:59:59.000Z

    Performance and scalability are critical quality attributes for server applications in Internet-facing business systems. These applications operate in dynamic environments with rapidly fluctuating user loads and resource levels, and unpredictable system faults. Adaptive (autonomic) systems research aims to augment such server applications with intelligent control logic that can detect and react to sudden environmental changes. However, developing this adaptive logic is complex in itself. In addition, executing the adaptive logic consumes processing resources, and hence may (paradoxically) adversely affect application performance. In this paper we describe an approach for developing high-performance adaptive server applications and the supporting technology. The Adaptive Server Framework (ASF) is built on standard middleware services, and can be used to augment legacy systems with adaptive behavior without needing to change the application business logic. Crucially, ASF provides built-in control loop components to optimize the overall application performance, which comprises both the business and adaptive logic. The control loop is based on performance models and allows systems designers to tune the performance levels simply by modifying high level declarative policies. We demonstrate the use of ASF in a case study.

  7. Adaptive motion mapping in pancreatic SBRT patients using Fourier transforms

    E-Print Network [OSTI]

    Jones, Bernard L; Miften, Moyed

    2015-01-01T23:59:59.000Z

    Recent studies suggest that 4DCT is unable to accurately measure respiratory-induced pancreatic tumor motion. In this work, we assessed the daily motion of pancreatic tumors treated with SBRT, and developed adaptive strategies to predict and account for this motion. The daily motion trajectory of pancreatic tumors during CBCT acquisition was calculated using a model which reconstructs the instantaneous 3D position in each 2D CBCT projection image. We developed a metric (termed "Spectral Coherence," SC) based on the Fourier frequency spectrum of motion in the SI direction, and analyzed the ability of SC to predict motion-based errors and classify patients according to motion characteristics. The amplitude of daily motion exceeded the predictions of pre-treatment 4DCT imaging by an average of 3.0 mm, 2.3 mm, and 3.5 mm in the AP, LR, and SI directions. SC was correlated with daily motion differences and tumor dose coverage. In a simulated adaptive protocol, target margins were adjusted based on SC, resulting in...

  8. Characterizing the Altered Cellular Proteome Induced by the Stress-Independent Activation of Heat Shock Factor 1

    E-Print Network [OSTI]

    Morimoto, Richard

    Characterizing the Altered Cellular Proteome Induced by the Stress- Independent Activation of Heat activation of heat shock factor 1 (HSF1), a stress-responsive transcription factor that induces-responsive signaling pathways such as the heat shock response (HSR).1,2 The HSR is an evolutionarily conserved, stress

  9. Adaptive control for optimizing microalgae production

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Adaptive control for optimizing microalgae production Francis Mairet Rafael Mu for light-limited microalgae culture. This controller regulates the light absorption factor, defined productivity under day-night cycles. Keywords: Nonlinear controller, Microalgae, Optimization, Biomass

  10. Exponential convergence with adaptive Monte Carlo

    SciTech Connect (OSTI)

    Booth, T.E.

    1997-11-01T23:59:59.000Z

    For over a decade, it has been known that exponential convergence on discrete transport problems was possible using adaptive Monte Carlo techniques. Now, exponential convergence has been empirically demonstrated on a spatially continuous problem.

  11. Adaptive Importance Sampling via Stochastic Convex Programming

    E-Print Network [OSTI]

    Adaptive Importance Sampling via Stochastic Convex Programming Ernest K. Ryu1 and Stephen P. Boyd1 Abstract We show that the variance of the Monte Carlo estimator that is importance sam- pled from

  12. Scalable Adaptive Multilevel Solvers for Multiphysics Problems

    SciTech Connect (OSTI)

    Xu, Jinchao

    2014-12-01T23:59:59.000Z

    In this project, we investigated adaptive, parallel, and multilevel methods for numerical modeling of various real-world applications, including Magnetohydrodynamics (MHD), complex fluids, Electromagnetism, Navier-Stokes equations, and reservoir simulation. First, we have designed improved mathematical models and numerical discretizaitons for viscoelastic fluids and MHD. Second, we have derived new a posteriori error estimators and extended the applicability of adaptivity to various problems. Third, we have developed multilevel solvers for solving scalar partial differential equations (PDEs) as well as coupled systems of PDEs, especially on unstructured grids. Moreover, we have integrated the study between adaptive method and multilevel methods, and made significant efforts and advances in adaptive multilevel methods of the multi-physics problems.

  13. Adaptive Reliability Analysis of Excavation Problems

    E-Print Network [OSTI]

    Park, Jun Kyung

    2012-10-19T23:59:59.000Z

    . This analysis couples the adaptive design capabilities of the observational method with updated reliability indices, to be used in risk-based design decisions. A probabilistic framework is developed to predict three-dimensional deformation profiles due...

  14. Robust adaptive control of switched systems

    E-Print Network [OSTI]

    El-Rifai, Khalid, 1979-

    2007-01-01T23:59:59.000Z

    In this thesis, robust adaptive controllers are developed for classes of switched nonlinear systems. Switched systems are those governed by differential equations, which undergo vector field switching due to sudden changes ...

  15. Adaptive optic demonstrators for extremely large telescopes 

    E-Print Network [OSTI]

    Campbell, Michael Aloysius

    2011-06-27T23:59:59.000Z

    The next generation of ground-based optical/infrared (IR) telescopes will have primary mirrors of up to 42 m. To take advantage of the large potential increase in angular resolution, adaptive optics will be essential to ...

  16. Adaptive sampling in autonomous marine sensor networks

    E-Print Network [OSTI]

    Eickstedt, Donald Patrick

    2006-01-01T23:59:59.000Z

    In this thesis, an innovative architecture for real-time adaptive and cooperative control of autonomous sensor platforms in a marine sensor network is described in the context of the autonomous oceanographic network scenario. ...

  17. Fast Adaptive Silhouette Area based Template Matching

    E-Print Network [OSTI]

    Zachmann, Gabriel

    Fast Adaptive Silhouette Area based Template Matching Daniel Mohr and Gabriel Zachmann If (Technical Informatics and Computer Systems) Prof. Dr. Gabriel Zachmann (Computer Graphics) Prof. Dr Template Matching Daniel Mohr and Gabriel Zachmann Clausthal University of Technology, Department

  18. A Logical Characterization of Adaptive Educational Hypermedia

    E-Print Network [OSTI]

    Henze, Nicola

    reference models for adaptive hypermedia, e.g. the AHAM Reference Model [4], or the Munich Reference Model [20]. Both, the AHAM and Munich Reference Model, extend the Dexter Hypertext Model [16], and pro- vide

  19. Convert! : the adaptive reuse of churches

    E-Print Network [OSTI]

    Kiley, Christopher John, 1972-

    2004-01-01T23:59:59.000Z

    This thesis examines the phenomenon of vacated churches and analyzes the major issues underlying their adaptive reuse in order to help promulgate an awareness of the range of successful strategies and solutions that are ...

  20. Challenges of Adapting to a Changing Climate

    E-Print Network [OSTI]

    Hurd, Brian H.

    2008-01-01T23:59:59.000Z

    of Global Climate Change on Agriculture: An Interpretiveon U.S. Agriculture, in THE IMPACT OF CLIMATE CHANGE ON THEclimate change and the potential roles for adaptation are more severe for ecosystems than they are for managed systems like agriculture.

  1. Anisotropic Grid Adaptation for Multiple Aerodynamic Outputs

    E-Print Network [OSTI]

    Venditti, David A.

    Anisotropic grid–adaptive strategies are presented for viscous flow simulations in which the accurate prediction of multiple aerodynamic outputs (such as the lift, drag, and moment coefficients) is required from a single ...

  2. Developmental Plasticity Links Local Adaptation and Evolutionary

    E-Print Network [OSTI]

    Badyaev, Alex

    Developmental Plasticity Links Local Adaptation and Evolutionary Diversification in Foraging, University of Arizona, Tucson, Arizona Developmental plasticity is thought to reconcile the constraining role morphology into adulthood, providing an opportunity to directly examine the links between plasticity of bone

  3. Asymptotic normality of urn models for clinical trials with delayed response

    E-Print Network [OSTI]

    Zhang, Li-Xin

    normality of Yn in the GFU model. Typically, clinical trials do not result in immediate outcomes ­ that isAsymptotic normality of urn models for clinical trials with delayed response F E I FA N G H U 1, Zhejiang, Hangzhou 310028, P. R. China. E-mail: lxzhang@mail.hz.zj.cn For response-adaptive clinical trials

  4. The Sponge Pump: The Role of Current Induced Flow in the Design of the Sponge Body Plan

    E-Print Network [OSTI]

    Yahel, Gitai

    The Sponge Pump: The Role of Current Induced Flow in the Design of the Sponge Body Plan Sally P filtration have estimated the energetic cost of pumping to be ,1% of its total metabolism implying there is little adaptive value to reducing the cost of pumping by using ``passive'' flow induced by the ambient

  5. Adaptive gain improves reactor control

    SciTech Connect (OSTI)

    Whatley, M.J.; Pott, D.C.

    1984-05-01T23:59:59.000Z

    An interesting application of the modern control theory technique called adaptive control is presently in use on a process located at a plant in the Standard Oil Co. (Ind.) system. The results of this application are: first, the transformation of an uncontrollable process to a controllable one; and, second, a significant economic savings to the corporation. It also shows that a detailed analysis of the mechanical, chemical and control systems can provide both the basis for revising an existing control system and some of the reasons why that system is inadequate. The contrast between classical and modern control theories is seen in four major areas. In classical systems, the controller manipulates the error to calculate its output. The error is subjected to a limited number of analog computing functions such as multiplication by a constant and integration. Each controller has one specific strategy--to hold the measured variable at the setpoint. And each controller controls only one variable, independent of all others. In a modern system, the controller can manipulate many different variables in addition to the error to compute its output. Its computing power is unlimited in a practical sense. It can do all classical computations plus many others, including a table look-up. The controller can independently change its strategy as a function of time or the condition of the process. It can also control many variables at one time to accomplish a complex objective. The implementation of a modern control theory project requires a good understanding of the dynamic, as well as the steady-state character of the process. As you can see we are limited only by our understanding of the process, our imagination, and the economics of the situation.

  6. Adaptation to water scarcity in glacier-dependent towns of the Indian Himalayas : impacts, adaptive responses, barriers, and solutions

    E-Print Network [OSTI]

    Sudhalkar, Amruta Anand

    2010-01-01T23:59:59.000Z

    Among the existing and projected impacts of climate change, impacts on water resources are expected to exacerbate the current and future threat of global water scarcity. Glacier-dependent societies are especially vulnerable ...

  7. The Durham ELT adaptive optics simulation platform

    E-Print Network [OSTI]

    Alastair Basden; Timothy Butterley; Richard Myers; Richard Wilson

    2006-11-09T23:59:59.000Z

    Adaptive optics systems are essential on all large telescopes where image quality is important. These are complex systems with many design parameters requiring optimisation before good performance can be achieved. The simulation of adaptive optics systems is therefore necessary to categorise the expected performance. This paper describes an adaptive optics simulation platform, developed at Durham University, which can be used to simulate adaptive optics systems on the largest proposed future extremely large telescopes (ELTs) as well as current systems. This platform is modular, object oriented and has the benefit of hardware application acceleration which can be used to improve the simulation performance, essential for ensuring that the run time of a given simulation is acceptable. The simulation platform described here can be highly parallelised using parallelisation techniques suited for adaptive optics simulation, whilst still offering the user complete control while the simulation is running. Results from the simulation of a ground layer adaptive optics system are provided as an example to demonstrate the flexibility of this simulation platform.

  8. Dipolar response of hydrated proteins

    E-Print Network [OSTI]

    Dmitry V. Matyushov

    2011-08-12T23:59:59.000Z

    The paper presents an analytical theory and numerical simulations of the dipolar response of hydrated proteins. The effective dielectric constant of the solvated protein, representing the average dipole moment induced at the protein by a uniform external field, shows a remarkable variation among the proteins studied by numerical simulations. It changes from 0.5 for ubiquitin to 640 for cytochrome c. The former value implies a negative dipolar susceptibility of ubiquitin, that is a dia-electric dipolar response and negative dielectrophoresis. It means that a protein carrying an average dipole of ~240 D is expected to repel from the region of a stronger electric field. This outcome is the result of a negative cross-correlation between the protein and water dipoles, compensating for the positive variance of the protein dipole in the overall dipolar susceptibility. This phenomenon can be characterized as overscreening of protein's dipole by the hydration shell. In contrast to the neutral ubiquitin, charged proteins studied here show para-electric dipolar response and positive dielectrophoresis. The protein-water dipolar cross-correlations are long-ranged, extending approximately 2 nm from the protein surface into the bulk. The analysis of numerical simulations suggests that the polarization of the protein-water interface is strongly affected by the distribution of the protein surface charge. This component of the protein dipolar response gains in importance for high frequencies, above the protein Debye peak, when the response of the protein dipole becomes dynamically arrested. The interface response found in simulations suggests a possibility of a positive increment of the high-frequency dielectric constant of the solution compared to the dielectric constant of the solvent, in support of the observed THz absorbance of protein solutions.

  9. IEEE INFOCOM 2001 1 Pricing Network Resources for Adaptive

    E-Print Network [OSTI]

    Wang, Xin

    , and provides a natural and equitable incentive for applications to adapt their service contract according

  10. Model Reference Adaptive Control Framework for Real Time Traffic

    E-Print Network [OSTI]

    Minnesota, University of

    Adaptive Control #12;12 Prescriptive Dynamic Traffic Assignment A Prediction Model and the Reference ModelModel Reference Adaptive Control Framework for Real Time Traffic Management Under Emergency Movement Volume Adaptive Controller Model Reference Adaptive Control (MRAC) Assumptions Super Zone Concept

  11. DCS1800/WCDMA ADAPTIVE VOLTAGE-CONTROLLED OSCILLATOR

    E-Print Network [OSTI]

    Serdijn, Wouter A.

    DCS1800/WCDMA ADAPTIVE VOLTAGE-CONTROLLED OSCILLATOR Aleksandar Tasiü, Wouter A. Serdijn and John R, an adaptive 2G/3G voltage-controlled oscillator (VCO) is described in this paper. For the DCS1800 operation with this reasoning, an adaptive 2G/3G voltage- controlled oscillator, meant for a dual-standard adaptive front

  12. Experimental investigation and constitutive modeling of the large deformation behavior of anisotropic steel sheets undergoing strain-induced phase transformation

    E-Print Network [OSTI]

    Beese, Allison M

    2011-01-01T23:59:59.000Z

    The strain-induced phase transformation from austenite to martensite is responsible for the high strength and ductility of TRansformation-Induced Plasticity (TRIP)- assisted steels. The large deformation behavior of ...

  13. DNA repair efficiency in germ cells and early mouse embryos and consequences for radiation-induced transgenerational genomic damage

    E-Print Network [OSTI]

    Marchetti, Francesco

    2009-01-01T23:59:59.000Z

    Kastan, M. B. (1997). DNA damage induces phosphorylation ofby ATM in response to DNA damage. Science 281, Barber, R. ,Nussenzweig, A. (2002). DNA damage-induced G2-M checkpoint

  14. Gain scheduling adaptive control strategies for HVDC systems to accommodate large disturbances

    SciTech Connect (OSTI)

    Reeve, J.; Sultan, M. (Univ. of Waterloo, Ontario (Canada))

    1994-02-01T23:59:59.000Z

    Techniques have been developed to permit the response of the controls for dc transmission systems to adapt to large system changes. A gain scheduling approach tunes the control as an on-line function of the effective short-circuit ratio and contingency indicators. The method has been tested by digital simulation, based on EMTP, of a back-to-back dc system. It has been found to be robust and control performance has been enhanced.

  15. Research Report Sensory experience determines enrichment-induced plasticity

    E-Print Network [OSTI]

    Kilgard, Michael P.

    Research Report Sensory experience determines enrichment-induced plasticity in rat auditory cortex in an enriched environment increases response strength and paired-pulse depression in the auditory cortex.L., Kilgard, M.P., 2004. Environmental enrichment improves response strength, threshold, selectivity

  16. Urban Studies, Vol. 40, No. 7, 000000, 2003 Induced Demand: A Microscopic Perspective

    E-Print Network [OSTI]

    Levinson, David M.

    . Introduction Transport forecasts often assume limited or no response of demand to changes in supply of the response of demand to supply, also referred to as induced or latent demand. According to the induced demand demand hypoth- esis to date has mostly been carried out at the aggregate level, considering state, metro

  17. Adaptive Plasticity and Plasticity as an Adaptation: A Selective Review of Plasticity in Animal Morphology and Life History

    E-Print Network [OSTI]

    Gotthard, Karl

    Adaptive Plasticity and Plasticity as an Adaptation: A Selective Review of Plasticity in Animal wide-ranging. All key REVIEW references should be cited. A summary is required. Adaptive plasticity and plasticity as an adaptation: a selective review of plasticity in animal morphology and life history Karl

  18. A hypoxia-inducible factor (HIF)-3? splicing variant, HIF-3?4 impairs angiogenesis in hypervascular malignant meningiomas with epigenetically silenced HIF-3?4

    SciTech Connect (OSTI)

    Ando, Hitoshi [Department of Neurosurgery, Nagoya University School of Medicine, Nagoya (Japan) [Department of Neurosurgery, Nagoya University School of Medicine, Nagoya (Japan); Department of Neurosurgery, Fukushima Medical University School of Medicine, Fukushima (Japan); Natsume, Atsushi, E-mail: anatsume@med.nagoya-u.ac.jp [Department of Neurosurgery, Nagoya University School of Medicine, Nagoya (Japan)] [Department of Neurosurgery, Nagoya University School of Medicine, Nagoya (Japan); Iwami, Kenichiro; Ohka, Fumiharu [Department of Neurosurgery, Nagoya University School of Medicine, Nagoya (Japan)] [Department of Neurosurgery, Nagoya University School of Medicine, Nagoya (Japan); Kuchimaru, Takahiro; Kizaka-Kondoh, Shinae [Department of Biomolecular Engineering, Tokyo Institute of Technology Graduate School of Bioscience and Biotechnology, Yokohama (Japan)] [Department of Biomolecular Engineering, Tokyo Institute of Technology Graduate School of Bioscience and Biotechnology, Yokohama (Japan); Ito, Kengo [National Center for Geriatrics and Gerontology, Aichi (Japan)] [National Center for Geriatrics and Gerontology, Aichi (Japan); Saito, Kiyoshi [Department of Neurosurgery, Fukushima Medical University School of Medicine, Fukushima (Japan)] [Department of Neurosurgery, Fukushima Medical University School of Medicine, Fukushima (Japan); Sugita, Sachi; Hoshino, Tsuneyoshi [MICRON Inc.Medical Facilities Support Department, Aichi (Japan)] [MICRON Inc.Medical Facilities Support Department, Aichi (Japan); Wakabayashi, Toshihiko [Department of Neurosurgery, Nagoya University School of Medicine, Nagoya (Japan)] [Department of Neurosurgery, Nagoya University School of Medicine, Nagoya (Japan)

    2013-03-29T23:59:59.000Z

    Highlights: ? HIF-3?4 is silenced by DNA methylation in meningiomas. ? Induction of HIF-3?4 impaired angiogenesis in meningiomas. ? Induction of HIF-3?4 impaired proliferation and oxygen-dependent metabolism. -- Abstract: Hypoxia inducible factor is a dominant regulator of adaptive cellular responses to hypoxia and controls the expression of a large number of genes regulating angiogenesis as well as metabolism, cell survival, apoptosis, and other cellular functions in an oxygen level-dependent manner. When a neoplasm is able to induce angiogenesis, tumor progression occurs more rapidly because of the nutrients provided by the neovasculature. Meningioma is one of the most hypervascular brain tumors, making anti-angiogenic therapy an attractive novel therapy for these tumors. HIF-3? has been conventionally regarded as a dominant-negative regulator of HIF-1?, and although alternative HIF-3? splicing variants are extensively reported, their specific functions have not yet been determined. In this study, we found that the transcription of HIF-3?4 was silenced by the promoter DNA methylation in meningiomas, and inducible HIF-3?4 impaired angiogenesis, proliferation, and metabolism/oxidation in hypervascular meningiomas. Thus, HIF-3?4 could be a potential molecular target in meningiomas.

  19. The Genomes of the Fungal Plant Pathogens Cladosporium fulvum and Dothistroma septosporum Reveal Adaptation to Different Hosts and Lifestyles But Also Signatures of Common Ancestry

    SciTech Connect (OSTI)

    de Wit, Pierre J. G. M.; van der Burgt, Ate; Okmen, Bilal; Stergiopoulos, Ioannis; Abd-Elsalam, Kamel A.; Aerts, Andrea L.; Bahkali, Ali H.; Beenen, Henriek G.; Chettri, Oranav; Cos, Murray P.; Datema, Erwin; de Vries, Ronald P.; DHillon, Braham; Ganley, Austen R.; Griffiths, Scott A.; Guo, Yanan; Gamelin, Richard C.; Henrissat, Bernard; Kabir, M. Shahjahan; Jashni, Mansoor Karimi; Kema, Gert; Klaubauf, Sylvia; Lapidus, Alla; Levasseur, Anthony; Lindquist, Erika; Mehrabi, Rahim; Ohm, Robin A.; Owen, Timothy J.; Salamov, Asaf; Schwelm, Arne; Schijlen, Elio; Sun, Hui; van den Burg, Harrold A.; van Burg, Roeland C. H. J.; Zhang, Shuguang; Goodwin, Stephen B.; Grigoriev, Igor V.; Collemare, Jerome; Bradshaw, Rosie E.

    2012-05-04T23:59:59.000Z

    We sequenced and compared the genomes of the Dothideomycete fungal plant pathogens Cladosporium fulvum (Cfu) (syn. Passalora fulva) and Dothistroma septosporum (Dse) that are closely related phylogenetically, but have different lifestyles and hosts. Although both fungi grow extracellularly in close contact with host mesophyll cells, Cfu is a biotroph infecting tomato, while Dse is a hemibiotroph infecting pine. The genomes of these fungi have a similar set of genes (70percent of gene content in both genomes are homologs), but differ significantly in size (Cfu >61.1-Mb; Dse 31.2-Mb), which is mainly due to the difference in repeat content (47.2percent in Cfu versus 3.2percent in Dse). Recent adaptation to different lifestyles and hosts is suggested by diverged sets of genes. Cfu contains an tomatinase gene that we predict might be required for detoxification of tomatine, while this gene is absent in Dse. Many genes encoding secreted proteins are unique to each species and the repeat-rich areas in Cfu are enriched for these species-specific genes. In contrast, conserved genes suggest common host ancestry. Homologs of Cfu effector genes, including Ecp2 and Avr4, are present in Dse and induce a Cf-Ecp2- and Cf-4-mediated hypersensitive response, respectively. Strikingly, genes involved in production of the toxin dothistromin, a likely virulence factor for Dse, are conserved in Cfu, but their expression differs markedly with essentially no expression by Cfu in planta. Likewise, Cfu has a carbohydrate-degrading enzyme catalog that is more similar to that of necrotrophs or hemibiotrophs and a larger pectinolytic gene arsenal than Dse, but many of these genes are not expressed in planta or are pseudogenized. Overall, comparison of their genomes suggests that these closely related plant pathogens had a common ancestral host but since adapted to different hosts and lifestyles by a combination of differentiated gene content, pseudogenization, and gene regulation.

  20. EcoAdapt Working Paper Series N1 Adaptation to climate change for local development

    E-Print Network [OSTI]

    Boyer, Edmond

    1 EcoAdapt Working Paper Series N°1 Adaptation to climate change for local development Análisis in terms of employment, water situation and land use, at a quantitative and qualitative level, in three and summer pastures, due to the geographic and climatic conditions. hal-01059368,version1-30Aug2014 #12

  1. A Rate-Adaptive Multimedia Multicasting Mechanism. . . 23 A Rate-Adaptive Multimedia Multicasting Mechanism in

    E-Print Network [OSTI]

    A Rate-Adaptive Multimedia Multicasting Mechanism. . . 23 A Rate-Adaptive Multimedia Multicasting and Multimedia Department ENST Bretagne, 2, rue de la Chataigneraie - CS 17607 35576 Cesson Sevigne Cedex rapidly. One of the major driving factors of WLANs is multimedia services such as VOD or HDTV delivered

  2. Adaptive and Non-Adaptive Distribution Functions for DSA Melanie Smith

    E-Print Network [OSTI]

    Mailler, Roger

    Adaptive and Non-Adaptive Distribution Functions for DSA Melanie Smith University of Tulsa 800 S. Tucker Drive Tulsa, OK 74104 melanie@utulsa.edu Sandip Sen University of Tulsa 800 S. Tucker Drive Tulsa, OK 74104 sandip-sen@utulsa.edu Roger Mailler University of Tulsa 800 S. Tucker Drive Tulsa, OK 74104

  3. Adapting to WisconsinAdapting to Wisconsin''ss Changing WatersChanging Waters

    E-Print Network [OSTI]

    Sheridan, Jennifer

    spells and droughts in some places, to colder cold spells and more violent storms, more intense flooding://wicci.wisc.edu #12;WICCI Identifying impacts and adaptation strategies Evaluate potential effects on industry, agriculture, tourism, and other human activities. Develop and recommend adaptation strategies. Mission: Assess

  4. In vivo transcranial cavitation threshold detection during ultrasound-induced bloodbrain barrier opening in mice

    E-Print Network [OSTI]

    Konofagou, Elisa E.

    In vivo transcranial cavitation threshold detection during ultrasound-induced blood­brain barrier cavitation threshold detection during ultrasound-induced blood­brain barrier opening in mice Yao-Sheng Tung1 cavitation response associated with blood­brain barrier (BBB) opening as induced by transcranial focused

  5. Advanced Demand Responsive Lighting

    E-Print Network [OSTI]

    Advanced Demand Responsive Lighting Host: Francis Rubinstein Demand Response Research Center demand responsive lighting systems ­ Importance of dimming ­ New wireless controls technologies · Advanced Demand Responsive Lighting (commenced March 2007) #12;Objectives · Provide up-to-date information

  6. HAZARDOUS MATERIALS EMERGENCY RESPONSE

    E-Print Network [OSTI]

    ANNEX Q HAZARDOUS MATERIALS EMERGENCY RESPONSE #12;ANNEX Q - HAZARDOUS MATERIALS EMERGENCY RESPONSE 03/10/2014 v.2.0 Page Q-1 PROMULGATION STATEMENT Annex Q: Hazardous Materials Emergency Response, and contents within, is a guide to how the University conducts a response specific to a hazardous materials

  7. Load attenuating passively adaptive wind turbine blade

    DOE Patents [OSTI]

    Veers, Paul S. (Albuquerque, NM); Lobitz, Donald W. (Albuquerque, NM)

    2003-01-01T23:59:59.000Z

    A method and apparatus for improving wind turbine performance by alleviating loads and controlling the rotor. The invention employs the use of a passively adaptive blade that senses the wind velocity or rotational speed, and accordingly modifies its aerodynamic configuration. The invention exploits the load mitigation prospects of a blade that twists toward feather as it bends. The invention includes passively adaptive wind turbine rotors or blades with currently preferred power control features. The apparatus is a composite fiber horizontal axis wind-turbine blade, in which a substantial majority of fibers in the blade skin are inclined at angles of between 15 and 30 degrees to the axis of the blade, to produces passive adaptive aeroelastic tailoring (bend-twist coupling) to alleviate loading without unduly jeopardizing performance.

  8. Load attenuating passively adaptive wind turbine blade

    DOE Patents [OSTI]

    Veers, Paul S.; Lobitz, Donald W.

    2003-01-07T23:59:59.000Z

    A method and apparatus for improving wind turbine performance by alleviating loads and controlling the rotor. The invention employs the use of a passively adaptive blade that senses the wind velocity or rotational speed, and accordingly modifies its aerodynamic configuration. The invention exploits the load mitigation prospects of a blade that twists toward feather as it bends. The invention includes passively adaptive wind turbine rotors or blades with currently preferred power control features. The apparatus is a composite fiber horizontal axis wind-turbine blade, in which a substantial majority of fibers in the blade skin are inclined at angles of between 15 and 30 degrees to the axis of the blade, to produces passive adaptive aeroelastic tailoring (bend-twist coupling) to alleviate loading without unduly jeopardizing performance.

  9. Response of continuous pipelines to tunnel induced ground deformations

    E-Print Network [OSTI]

    Ieronymaki, Evangelia S

    2011-01-01T23:59:59.000Z

    This thesis develops analytical solutions for estimating the bending moments and axial loads in a buried pipeline due to ground movements caused by tunnel construction in soft ground. The solutions combine closed-form, ...

  10. Induced Responses to Herbivory and Increased Plant Performance

    E-Print Network [OSTI]

    Agrawal, Anurag

    plant performance. Lifetime plant performance was evalu- ated for wild radish (Raphanus sativus L. Because mean seed mass significantly affected plant fitness in pre- vious experiments with Raphanus (12

  11. antibody responses induced: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NANOLAMINATES . Open Access Theses and Dissertations Summary: ??To characterize the self-propagating, high-temperature exothermic alloying reactions of NiAl nanoscaled...

  12. Chemical Spill Response Procedure Initial Response

    E-Print Network [OSTI]

    Chemical Spill Response Procedure Initial Response 1. Advise lab occupants of the spill-4500. If not, continue with step 4. Clean-Up 4. Ensure the spill area has adequate ventilation to clear gases is absorbed. If necessary, add more neutralizing powder. 9. If cleaning up a solvent, proceed to step 13. 10

  13. Conjugate adaptive optics in widefield microscopy with an extended-source wavefront sensor

    E-Print Network [OSTI]

    Li, Jiang; Paudel, Hari; Barankov, Roman; Bifano, Thomas; Mertz, Jerome

    2015-01-01T23:59:59.000Z

    Adaptive optics is a strategy to compensate for sample-induced aberrations in microscopy applications. Generally, it requires the presence of "guide stars" in the sample to serve as localized reference targets. We describe an implementation of conjugate adaptive optics that is amenable to widefield (i.e. non-scanning) microscopy, and can provide aberration corrections over potentially large fields of view without the use of guide stars. A unique feature of our implementation is that it is based on wavefront sensing with a single-shot partitioned-aperture sensor that provides large dynamic range compatible with extended samples. Combined information provided by this sensor and the imaging camera enable robust image de-blurring based on a rapid estimation of sample and aberrations obtained by closed-loop feedback. We present the theoretical principle of our technique and proof of concept experimental demonstrations.

  14. Cavitation-resistant inducer

    DOE Patents [OSTI]

    Dunn, Charlton (Calabasas, CA); Subbaraman, Maria R. (Canoga Park, CA)

    1989-01-01T23:59:59.000Z

    An improvement in an inducer for a pump wherein the inducer includes a hub, a plurality of radially extending substantially helical blades and a wall member extending about and encompassing an outer periphery of the blades. The improvement comprises forming adjacent pairs of blades and the hub to provide a substantially rectangular cross-sectional flow area which cross-sectional flow area decreases from the inlet end of the inducer to a discharge end of the inducer, resulting in increased inducer efficiency improved suction performance, reduced susceptibility to cavitation, reduced susceptibility to hub separation and reduced fabrication costs.

  15. Cavitation-resistant inducer

    DOE Patents [OSTI]

    Dunn, C.; Subbaraman, M.R.

    1989-06-13T23:59:59.000Z

    An improvement in an inducer for a pump is disclosed wherein the inducer includes a hub, a plurality of radially extending substantially helical blades and a wall member extending about and encompassing an outer periphery of the blades. The improvement comprises forming adjacent pairs of blades and the hub to provide a substantially rectangular cross-sectional flow area which cross-sectional flow area decreases from the inlet end of the inducer to a discharge end of the inducer, resulting in increased inducer efficiency improved suction performance, reduced susceptibility to cavitation, reduced susceptibility to hub separation and reduced fabrication costs. 11 figs.

  16. Grid and basis adaptive polynomial chaos techniques for sensitivity and uncertainty analysis

    SciTech Connect (OSTI)

    Perkó, Zoltán, E-mail: Z.Perko@tudelft.nl; Gilli, Luca, E-mail: Gilli@nrg.eu; Lathouwers, Danny, E-mail: D.Lathouwers@tudelft.nl; Kloosterman, Jan Leen, E-mail: J.L.Kloosterman@tudelft.nl

    2014-03-01T23:59:59.000Z

    The demand for accurate and computationally affordable sensitivity and uncertainty techniques is constantly on the rise and has become especially pressing in the nuclear field with the shift to Best Estimate Plus Uncertainty methodologies in the licensing of nuclear installations. Besides traditional, already well developed methods – such as first order perturbation theory or Monte Carlo sampling – Polynomial Chaos Expansion (PCE) has been given a growing emphasis in recent years due to its simple application and good performance. This paper presents new developments of the research done at TU Delft on such Polynomial Chaos (PC) techniques. Our work is focused on the Non-Intrusive Spectral Projection (NISP) approach and adaptive methods for building the PCE of responses of interest. Recent efforts resulted in a new adaptive sparse grid algorithm designed for estimating the PC coefficients. The algorithm is based on Gerstner's procedure for calculating multi-dimensional integrals but proves to be computationally significantly cheaper, while at the same it retains a similar accuracy as the original method. More importantly the issue of basis adaptivity has been investigated and two techniques have been implemented for constructing the sparse PCE of quantities of interest. Not using the traditional full PC basis set leads to further reduction in computational time since the high order grids necessary for accurately estimating the near zero expansion coefficients of polynomial basis vectors not needed in the PCE can be excluded from the calculation. Moreover the sparse PC representation of the response is easier to handle when used for sensitivity analysis or uncertainty propagation due to the smaller number of basis vectors. The developed grid and basis adaptive methods have been implemented in Matlab as the Fully Adaptive Non-Intrusive Spectral Projection (FANISP) algorithm and were tested on four analytical problems. These show consistent good performance both in terms of the accuracy of the resulting PC representation of quantities and the computational costs associated with constructing the sparse PCE. Basis adaptivity also seems to make the employment of PC techniques possible for problems with a higher number of input parameters (15–20), alleviating a well known limitation of the traditional approach. The prospect of larger scale applicability and the simplicity of implementation makes such adaptive PC algorithms particularly appealing for the sensitivity and uncertainty analysis of complex systems and legacy codes.

  17. Spinning Reserve From Responsive Loads

    SciTech Connect (OSTI)

    Kirby, B.J.

    2003-04-08T23:59:59.000Z

    Responsive load is the most underutilized reliability resource available to the power system today. It is currently not used at all to provide spinning reserve. Historically there were good reasons for this, but recent technological advances in communications and controls have provided new capabilities and eliminated many of the old obstacles. North American Electric Reliability Council (NERC), Federal Energy Regulatory Commission (FERC), Northeast Power Coordinating Council (NPCC), New York State Reliability Council (NYSRC), and New York Independent System Operator (NYISO) rules are beginning to recognize these changes and are starting to encourage responsive load provision of reliability services. The Carrier ComfortChoice responsive thermostats provide an example of these technological advances. This is a technology aimed at reducing summer peak demand through central control of residential and small commercial air-conditioning loads. It is being utilized by Long Island Power Authority (LIPA), Consolidated Edison (ConEd), Southern California Edison (SCE), and San Diego Gas and Electric (SDG&E). The technology is capable of delivering even greater response in the faster spinning reserve time frame (while still providing peak reduction). Analysis of demand reduction testing results from LIPA during the summer of 2002 provides evidence to back up this claim. It also demonstrates that loads are different from generators and that the conventional wisdom, which advocates for starting with large loads as better ancillary service providers, is flawed. The tempting approach of incrementally adapting ancillary service requirements, which were established when generators were the only available resources, will not work. While it is easier for most generators to provide replacement power and non-spinning reserve (the slower response services) than it is to supply spinning reserve (the fastest service), the opposite is true for many loads. Also, there is more financial reward for supplying spinning reserve than for supplying the other reserve services as a result of the higher spinning reserve prices. The LIPAedge program (LIPA's demand reduction program using Carrier ComfortChoice thermostats) provides an opportunity to test the use of responsive load for spinning reserve. With potentially 75 MW of spinning reserve capability already installed, this test program can also make an important contribution to the capacity needs of Long Island during the summer of 2003. Testing could also be done at ConEd ({approx}30 MW), SCE ({approx}15 MW), and/or SDG&E ({approx}15 MW). This paper is divided into six chapters. Chapter 2 discusses the contingency reserve ancillary services, their functions in supporting power system reliability, and their technical requirements. It also discusses the policy and tariff requirements and attempts to distinguish between ones that are genuinely necessary and ones that are artifacts of the technologies that were historically used to provide the services. Chapter 3 discusses how responsive load could provide contingency reserves (especially spinning reserve) for the power system. Chapter 4 specifically discusses the Carrier ComfortChoice responsive thermostat technology, the LIPAedge experience with that technology, and how the technology could be used to supply spinning reserve. Chapter 5 discusses a number of unresolved issues and suggests areas for further research. Chapter 6 offers conclusions and recommendations.

  18. Adaptive Training for Large Vocabulary Continuous

    E-Print Network [OSTI]

    Hain, Thomas

    Adaptive Training for Large Vocabulary Continuous Speech Recognition Kai Yu Hughes Hall College for the degree of Doctor of Philosophy #12;ii Summary In recent years, there has been a trend towards training is to train hidden Markov models (HMMs) on the whole data set as if all data comes from a single acoustic

  19. Semantic Web Technologies for the Adaptive Web

    E-Print Network [OSTI]

    Nejdl, Wolfgang

    23 Semantic Web Technologies for the Adaptive Web Peter Dolog1 and Wolfgang Nejdl2 1 Department.de Abstract. Ontologies and reasoning are the key terms brought into focus by the semantic web community. Formal representation of ontologies in a common data model on the web can be taken as a foundation

  20. Provenance Meets Adaptive Hypermedia Evgeny Knutov

    E-Print Network [OSTI]

    De Bra, Paul

    Provenance Meets Adaptive Hypermedia Evgeny Knutov Department of Computer Science Eindhoven University of Technology P.O. Box 513, 5600 MB Eindhoven, the Netherlands e.knutov@tue.nl Paul De Bra Department of Computer Science Eindhoven University of Technology P.O. Box 513, 5600 MB Eindhoven

  1. Adaptive Scheduling Algorithms for Planet Searches

    E-Print Network [OSTI]

    Eric B. Ford

    2007-12-17T23:59:59.000Z

    High-precision radial velocity planet searches have surveyed over ~2000 nearby stars and detected over ~200 planets. While these same stars likely harbor many additional planets, they will become increasingly challenging to detect, as they tend to have relatively small masses and/or relatively long orbital periods. Therefore, observers are increasing the precision of their observations, continuing to monitor stars over decade timescales, and also preparing to survey thousands more stars. Given the considerable amounts of telescope time required for such observing programs, it is important use the available resources as efficiently as possible. Previous studies have found that a wide range of predetermined scheduling algorithms result in planet searches with similar sensitivities. We have developed adaptive scheduling algorithms which have a solid basis in Bayesian inference and information theory and also are computationally feasible for modern planet searches. We have performed Monte Carlo simulations of plausible planet searches to test the power of adaptive scheduling algorithms. Our simulations demonstrate that planet searches performed with adaptive scheduling algorithms can simultaneously detect more planets, detect less massive planets, and measure orbital parameters more accurately than comparable surveys using a non-adaptive scheduling algorithm. We expect that these techniques will be particularly valuable for the N2K radial velocity planet search for short-period planets as well as future astrometric planet searches with the Space Interferometry Mission which aim to detect terrestrial mass planets.

  2. A Middleware Framework for the Adaptive Home

    E-Print Network [OSTI]

    Dommel, Hans-Peter

    -friendly access to customized energy-aware home control, as well as the basic ambient intelligence to make a home adapt to user behavior and environmental constraints. Keywords. Network middleware for smart homes behavior. Newer developments in outfitting homes with powerful telematic intelligence [3, 4] catering

  3. Adaptive wavelet deconvolution for strongly mixing sequences

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Adaptive wavelet deconvolution for strongly mixing sequences Christophe Chesneau Abstract square error over Besov balls, we explore the performances of two wavelet estimators: a standard linear, Strongly mixing, Adap- tivity, Wavelets, Hard thresholding. AMS 2000 Subject Classifications: 62G07, 62G20

  4. IBM Software Data Sheet IBM adaptive threat

    E-Print Network [OSTI]

    IBM Software Data Sheet IBM adaptive threat protection Stay ahead of security threats with a state-of-the-art network protection engine Highlights Identify high-risk threats and zero-day attacks with protocol-based, behavioral anomaly detection Protect end users against the latest web-based threats, such as SQL injection

  5. Adaptive, full-spectrum solar energy system

    DOE Patents [OSTI]

    Muhs, Jeffrey D.; Earl, Dennis D.

    2003-08-05T23:59:59.000Z

    An adaptive full spectrum solar energy system having at least one hybrid solar concentrator, at least one hybrid luminaire, at least one hybrid photobioreactor, and a light distribution system operably connected to each hybrid solar concentrator, each hybrid luminaire, and each hybrid photobioreactor. A lighting control system operates each component.

  6. Adaptation in constant utility nonstationary environments

    E-Print Network [OSTI]

    Littman, Michael L.

    ­stationary environments are so pathological. Even if the environment, when viewed as a monolithic function, may of the results created by the organism over some given lifespan determines the organism's fitness. The nasty, the fitness produced by any single mapping will be at the chance level. The adaptive challenge is to produce

  7. CLIMATE CHANGE ADAPTATIONS FOR LOCAL WATER MANAGEMENT

    E-Print Network [OSTI]

    CLIMATE CHANGE ADAPTATIONS FOR LOCAL WATER MANAGEMENT IN THE SAN FRANCISCO BAY AREA A White Paper from the California Energy Commission's California Climate Change Center JULY 2012 CEC Climate change will affect both sea level and the temporal and spatial distribution of runoff

  8. An Infrastructure for Adaptive Dynamic Optimization

    E-Print Network [OSTI]

    Amarasinghe, Saman

    An Infrastructure for Adaptive Dynamic Optimization Derek Bruening, Timothy Garnett, and Saman,timothyg,saman}@lcs.mit.edu Abstract Dynamic optimization is emerging as a promising ap- proach to overcome many of the obstacles static optimizations, there are very few for developing dynamic optimizations. We present a framework

  9. Grid adaptation for multiscale plasma simulations

    E-Print Network [OSTI]

    Ito, Atsushi

    Grid adaptation for multiscale plasma simulations Gian Luca Delzanno Los Alamos National Laboratory In collaboration with L. Chacon and J.M. Finn #12;delzanno@lanl.gov Outline · Introduction and motivation · Grid tests · New directions · Conclusions #12;delzanno@lanl.gov Outline · Introduction and motivation · Grid

  10. Climate Change Basics: Science, Adaptation, & Mitigation

    E-Print Network [OSTI]

    Fox-Kemper, Baylor

    Science Global atmospheric concentrations of carbon dioxide, methane and nitrous oxide have increased from ice cores spanning many thousands of years. The global increases in carbon dioxide concentrationClimate Change Basics: Science, Adaptation, & Mitigation with a Family Forest Perspective Baylor

  11. Adaptation, Speciation, and Convergence: A Hierarchical Analysis of Adaptive Radiation in Caribbean Anolis Lizards

    E-Print Network [OSTI]

    Losos, Jonathan B.; Glor, Richard E.; Kolbe, Jason J.; Nicholson, Kirsten

    2006-05-01T23:59:59.000Z

    Caribbean Anolis lizards are a classic case of adaptive radiation, repeated four times across islands of the Greater Antilles. On each island, very similar patterns of evolutionary divergence have occurred, resulting in the evolution of the same set...

  12. The Complexity of Adaptation to Climate Change. Exploring adaptation in Rio Grande, Ecuador 

    E-Print Network [OSTI]

    Argudo, Cristina

    2014-11-27T23:59:59.000Z

    Climate change has become one of the most challenging problems in terms of development, having adverse effects in populations that are already vulnerable to other stressors. At present, the importance of adaptation to climate change has been widely...

  13. Funding for adaptation to climate change : the case of Surat

    E-Print Network [OSTI]

    Patel, Toral

    2014-01-01T23:59:59.000Z

    The need for cities to adapt to climate change is widely acknowledged, yet the question of adaptation finance remains uncertain. Unable to access global climate funds, cities must seek out alternative sources to support ...

  14. Learning from Monitoring & Evaluation a blueprint for an adaptive organisation

    E-Print Network [OSTI]

    Learning from Monitoring & Evaluation ­ a blueprint for an adaptive organisation Learning from Monitoring & Evaluation ­ a blueprint for an adaptive organisation Jake Morris and Anna Lawrence Social & Economic Research Group, Forest Research Aim and structure Learning is an essential characteristic

  15. Adaptive array antenna design for wireless communication systems 

    E-Print Network [OSTI]

    Noordin, Nurul Hazlina

    2013-11-28T23:59:59.000Z

    Adaptive array antennas use has been limited to non-commercial applications due to their high cost and hardware complexity. The implementation cost of adaptive array antennas can be kept to a minimum by using cost effective ...

  16. Evaluation and Adaptation of 5-Cycle Fuel Economy Testing and...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Adaptation of 5-Cycle Fuel Economy Testing and Calculations for HEVs and PHEVs Evaluation and Adaptation of 5-Cycle Fuel Economy Testing and Calculations for HEVs and PHEVs 2012...

  17. adaptive process control: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 ADAPTIVE OPTICS CONTROL FOR LASER MATERIAL PROCESSING Mathematics Websites Summary: ADAPTIVE OPTICS...

  18. Geometric Structure of the Adaptive Controller of the Human Arm

    E-Print Network [OSTI]

    Shadmehr, Reza

    1993-07-01T23:59:59.000Z

    The objects with which the hand interacts with may significantly change the dynamics of the arm. How does the brain adapt control of arm movements to this new dynamic? We show that adaptation is via composition of a ...

  19. Adaptive Treatment Strategies Getting SMART About Developing Individualized

    E-Print Network [OSTI]

    Murphy, Susan A.

    Other names are dynamic treatment regimes, treatment algorithms, stepped care models, expert systems: prevent relapse to alcohol abuse · Critical treatment decisions: which treatment to provide first?; which1 Adaptive Treatment Strategies Getting SMART About Developing Individualized Sequences of Adaptive

  20. adaptive fourier analyzer: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    view or analyze the problem in n ways (n >2) Though we have defined these n- adaptive fuzzy models theorectically we are not in a position to get a n-adaptive fuzzy model for n...

  1. Accelerated Adaptive Markov Chain for Partition Function Computation

    E-Print Network [OSTI]

    Keinan, Alon

    Accelerated Adaptive Markov Chain for Partition Function Computation Stefano Ermon, Carla P. Gomes Ithaca NY 14853, U.S.A. Abstract We propose a novel Adaptive Markov Chain Monte Carlo algorithm

  2. Climate Change Adaptation: A Collective Action Perspective on Federalism Considerations

    E-Print Network [OSTI]

    Glicksman, Robert L.; Levy, Richard E.

    2010-01-01T23:59:59.000Z

    adaptation to minimize the adverse effects of climate change. Climate change adaptation is designed to increase the resilience of natural and human ecosystems to the threats posed by a changing environment. Although an extensive literature concerning...

  3. Performance of Adaptive DualDropping ILUT Preconditioners in Semiconductor

    E-Print Network [OSTI]

    Zhang, Jun

    Performance of Adaptive Dual­Dropping ILUT Preconditioners in Semiconductor Dopant Diffusion for iterative solution of sparse linear systems arising in semiconductor dopant diffusion modeling resolution, timestep in the adaptive ODE integrator and the problem physics. Key words: semiconductor TCAD

  4. Adaptive Robust Control of Robot Manipulators: Theory and Comparative Experiments

    E-Print Network [OSTI]

    Yao, Bin

    of the system such as gravitational load vary from a task to another, and, may not be precisely known in advance-based or direct adaptive control 21 , in which adaptation laws are used to adjust controller gains instead

  5. The Binding of Learning to Action in Motor Adaptation

    E-Print Network [OSTI]

    Gonzalez Castro, Luis Nicolas

    In motor tasks, errors between planned and actual movements generally result in adaptive changes which reduce the occurrence of similar errors in the future. It has commonly been assumed that the motor adaptation arising ...

  6. Ellipsoidal Oscillations Induced by Substellar Companions: A Prospect for the Kepler Mission

    E-Print Network [OSTI]

    Eric Pfahl; Phil Arras; Bill Paxton

    2007-04-15T23:59:59.000Z

    Hundreds of substellar companions to solar-type stars will be discovered with the Kepler satellite. Kepler's extreme photometric precision gives access to low-amplitude stellar variability contributed by a variety of physical processes. We discuss in detail the periodic flux modulations arising from the tidal force on the star due to a substellar companion. An analytic expression for the variability is derived in the equilibrium-tide approximation. We demonstrate analytically and through numerical solutions of the linear, nonadiabatic stellar oscillation equations that the equilibrium-tide formula works extremely well for stars of mass <1.4 Msun with thick surface convection zones. More massive stars with largely radiative envelopes do not conform to the equilibrium-tide approximation and can exhibit flux variations $\\ga$10 times larger than naive estimates. Over the full range of stellar masses considered, we treat the oscillatory response of the convection zone by adapting a prescription that A. J. Brickhill developed for pulsating white dwarfs. Compared to other sources of periodic variability, the ellipsoidal lightcurve has a distinct dependence on time and system parameters. We suggest that ellipsoidal oscillations induced by giant planets may be detectable from as many as ~100 of the 10^5 Kepler target stars. (Abridged)

  7. Optimal adaptive control of cascading power grid failures

    E-Print Network [OSTI]

    Daniel Bienstock

    2010-12-17T23:59:59.000Z

    Dec 17, 2010 ... Abstract: We describe experiments with parallel algorithms for computing adaptive controls for attenuating power grid cascading failures.

  8. Genomic islands predict functional adaptation in marine actinobacteria

    E-Print Network [OSTI]

    Penn, Kevin

    2010-01-01T23:59:59.000Z

    Ecological adaptations among bacterial populations have been linked to genomic islands, strain-specific regions of DNA that house

  9. BIA Request for Proposals for Climate Adaptation Grants for Tribes

    Broader source: Energy.gov [DOE]

    Download the Bureau of Indian Affairs Request for Proposals for Climate Adaptation Grants for Tribes, due November 29.

  10. Communication adapter for use with a drilling component

    DOE Patents [OSTI]

    Hall, David R. (Provo, UT); Pixton, David S. (Lehi, UT); Hall; Jr.; H. Tracy (Provo, UT); Bradford, Kline (Orem, UT); Rawle, Michael (Springville, UT)

    2007-04-03T23:59:59.000Z

    A communication adapter is disclosed that provides for removable attachment to a drilling component when the drilling component is not actively drilling and for communication with an integrated transmission system in the drilling component. The communication adapter comprises a data transmission coupler that facilitates communication between the drilling component and the adapter, a mechanical coupler that facilitates removable attachment of the adapter to the drilling component, and a data interface.

  11. Automated Web Page Synthesis in Adaptive Web Systems

    E-Print Network [OSTI]

    Ghorbani, Ali

    Automated Web Page Synthesis in Adaptive Web Systems Hossein Sadat and Ali Ghorbani Intelligent, Canada {t15h7,ghorbani}@unb.ca Abstract. An adaptive Web system adapts the Web pages to its users, based of the system. In this paper, we formalize dynamic generation of Web pages and refer to it as Web page synthesis

  12. MEDIA RESOURCES ADAPTATION FOR LIMITED DEVICES TAYEB LEMLOUMA1

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    MEDIA RESOURCES ADAPTATION FOR LIMITED DEVICES TAYEB LEMLOUMA1 ; NABIL LAYADA1 1 WAM Project, INRIA.Lemlouma@inrialpes.fr; Nabil.Layaida@inrialpes.fr In this paper, we define a framework for media resources manipulation in an adaptive content delivery system. We discuss the media resources manipulation in an adaptation

  13. An Adaptive Kalman Filter for Removing Baseline Wandering in ECG

    E-Print Network [OSTI]

    Povinelli, Richard J.

    An Adaptive Kalman Filter for Removing Baseline Wandering in ECG Signals MA Mneimneh, EE Yaz, MT to baseline removal. This paper proposes an adaptive Kalman filter for the real time re- moval of baseline is used with an adaptive Kalman filter to estimate the state variables, including the baseline wandering

  14. Adaptive Power Controlled Routing for Underwater Sensor Networks

    E-Print Network [OSTI]

    Zhou, Shengli

    Adaptive Power Controlled Routing for Underwater Sensor Networks Manal Al-Bzoor, Yibo Zhu, Jun Liu of an in- terest packet sent by sink nodes. We use adaptive power control to send at high power level the sink nodes using shortest end to end paths. By using adaptive power control over concentric layered

  15. Semantic Multimedia Document Adaptation with Functional Annotations Sebastien Laborie

    E-Print Network [OSTI]

    Joseph Fourier Grenoble-I, Université

    Semantic Multimedia Document Adaptation with Functional Annotations S´ebastien Laborie IRIT ­ Paul of presentation contexts for multimedia documents requires the adaptation of document specifica- tions. In an earlier work, we have proposed a seman- tic adaptation framework for multimedia documents. This framework

  16. Some Computational Problems Arising in Adaptive Optics Imaging Systems

    E-Print Network [OSTI]

    Plemmons, Robert J.

    Some Computational Problems Arising in Adaptive Optics Imaging Systems Robert J. Plemmons \\Lambda numerical linear algebra tech­ niques in adaptive optics imaging control computations. Real­time adaptive optics is a means for enhancing the resolution of ground based, optical telescopes beyond the limits

  17. Checking Sequence Construction Using Adaptive and Preset Distinguishing Sequences

    E-Print Network [OSTI]

    Jourdan, Guy-Vincent

    Checking Sequence Construction Using Adaptive and Preset Distinguishing Sequences Robert M. Hierons of a preset dis- tinguishing sequence for constructing checking sequences. It has been shown that an adaptive distinguishing sequence is sufficient for these methods. This result is significant because adaptive

  18. Grid adaptation for multiscale plasma simulations Gian Luca Delzanno

    E-Print Network [OSTI]

    Ito, Atsushi

    Grid adaptation for multiscale plasma simulations Gian Luca Delzanno Los Alamos National Laboratory tools need to be developed to bridge the gap between these disparate scales. Grid adaptation is one of such tools, useful to address multiple length scales, and we present a new powerful grid adaptation method

  19. Phenotypic plasticity facilitates recurrent rapid adaptation to introduced predators

    E-Print Network [OSTI]

    Pfrender, Michael

    Phenotypic plasticity facilitates recurrent rapid adaptation to introduced predators Alison G) A central role for phenotypic plasticity in adaptive evolution is often posited yet lacks empirical support of preexisting developmental pathways, producing rapid adaptive change. We examined the role of plasticity

  20. Adaptation Control in Adaptive Hypermedia Systems Hongjing Wu, Paul De Bra, Ad Aerts, GeertJan Houben

    E-Print Network [OSTI]

    De Bra, Paul

    model for the architecture of adaptive hypermedia applications: AHAM (for Adaptive Hypermedia Application Model) [DHW99], which is an extension of the Dexter hypermedia reference model [HS90, HS94]. AHAM

  1. Adaptation Control in Adaptive Hypermedia Systems Hongjing Wu, Paul De Bra, Ad Aerts, Geert-Jan Houben

    E-Print Network [OSTI]

    Houben, Geert-Jan

    model for the architecture of adaptive hypermedia applications: AHAM (for Adaptive Hypermedia Application Model) [DHW99], which is an extension of the Dexter hypermedia reference model [HS90, HS94]. AHAM

  2. SU-E-J-153: MRI Based, Daily Adaptive Radiotherapy for Rectal Cancer: Contour Adaptation

    SciTech Connect (OSTI)

    Kleijnen, J; Burbach, M; Verbraeken, T; Weggers, R; Zoetelief, A; Reerink, O; Lagendijk, J; Raaymakers, B; Asselen, B [University Medical Center Utrecht, Utrecht (Netherlands)

    2014-06-01T23:59:59.000Z

    Purpose: A major hurdle in adaptive radiotherapy is the adaptation of the planning MRI's delineations to the daily anatomy. We therefore investigate the accuracy and time needed for online clinical target volume (CTV) adaptation by radiation therapists (RTT), to be used in MRI-guided adaptive treatments on a MRI-Linac (MRL). Methods: Sixteen patients, diagnosed with early stage rectal cancer, underwent a T2-weighted MRI prior to each fraction of short-course radiotherapy, resulting in 4–5 scans per patient. On these scans, the CTV was delineated according to guidelines by an experienced radiation oncologist (RO) and considered to be the gold standard. For each patient, the first MRI was considered as the planning MRI and matched on bony anatomy to the 3–4 daily MRIs. The planning MRI's CTV delineation was rigidly propagated to the daily MRI scans as a proposal for adaptation. Three RTTs in training started the adaptation of the CTV conform guidelines, after a two hour training lecture and a two patient (n=7) training set. To assess the inter-therapist variation, all three RTTs altered delineations of 3 patients (n=12). One RTT altered the CTV delineations (n=53) of the remaining 11 patients. Time needed for adaptation of the CTV to guidelines was registered.As a measure of agreement, the conformity index (CI) was determined between the RTTs' delineations as a group. Dice similarity coefficients were determined between delineations of the RTT and the RO. Results: We found good agreement between RTTs' and RO's delineations (average Dice=0.91, SD=0.03). Furthermore, the inter-observer agreement between the RTTs was high (average CI=0.94, SD=0.02). Adaptation time reduced from 10:33 min (SD= 3:46) to 2:56 min (SD=1:06) between the first and last ten delineations, respectively. Conclusion: Daily CTV adaptation by RTTs, seems a feasible and safe way to introduce daily, online MRI-based plan adaptation for a MRL.

  3. Friction Induced Skin Tags

    E-Print Network [OSTI]

    Allegue, Francisco; Fachal, Carmen; Pérez-Pérez, Lidia

    2008-01-01T23:59:59.000Z

    Duplantis KL, Jones BH. Friction blisters. Pathophysiology,Friction Induced Skin Tags Francisco Allegue MD 1 , Carmenetiopathogenic role for friction. Introduction Skin tags (

  4. RUMINAL ADAPTATION TO INCREASING LEVELS OF CONCENTRATES

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    .0 % citrus pulp, 1.0 % lard, 7.0 % sugarbeet pulp, 3.3 % oat husk meal, 2.0 % coconut expeller and 2-chromatography. The rate of lactate fermentation was measured by incubation of 10 ml rumen fluid (taken at 14.00 h) with 1. If adaptation occurs one should expect an increase of lactate and a higher rate of L- lactate fermentation

  5. Robust adaptive control of HVDC systems

    SciTech Connect (OSTI)

    Reeve, J.; Sultan, M. (Univ. of Waterloo, Ontario (Canada))

    1994-07-01T23:59:59.000Z

    The transient performance of an HVDC power system is highly dependent on the parameters of the current/voltage regulators of the converter controls. In order to better accommodate changes in system structure or dc operating conditions, this paper introduces a new adaptive control strategy. The advantages of automatic tuning for continuous fine tuning are combined with predetermined gain scheduling in order to achieve robustness for large disturbances. Examples are provided for a digitally simulated back-to-back dc system.

  6. Optimization Online - Adaptive Robust Optimization with Dynamic ...

    E-Print Network [OSTI]

    Alvaro Lorca

    2014-09-29T23:59:59.000Z

    Sep 29, 2014 ... Abstract: The exceptional benefits of wind power as an environmentally responsible renewable energy resource have led to an increasing ...

  7. Demand response enabling technology development

    E-Print Network [OSTI]

    Arens, Edward; Auslander, David; Huizenga, Charlie

    2008-01-01T23:59:59.000Z

    behavior in developing a demand response future. Phase_II_Demand Response Enabling Technology Development Phase IIYi Yuan The goal of the Demand Response Enabling Technology

  8. Demand Response Spinning Reserve Demonstration

    E-Print Network [OSTI]

    2007-01-01T23:59:59.000Z

    F) Enhanced ACP Date RAA ACP Demand Response – SpinningReserve Demonstration Demand Response – Spinning Reservesupply spinning reserve. Demand Response – Spinning Reserve

  9. Demand response enabling technology development

    E-Print Network [OSTI]

    2006-01-01T23:59:59.000Z

    Demand Response Enabling Technology Development Phase IEfficiency and Demand Response Programs for 2005/2006,Application to Demand Response Energy Pricing” SenSys 2003,

  10. Automated Demand Response and Commissioning

    E-Print Network [OSTI]

    Piette, Mary Ann; Watson, David S.; Motegi, Naoya; Bourassa, Norman

    2005-01-01T23:59:59.000Z

    and Demand Response in Commercial Buildings”, Lawrencesystems. Demand Response using HVAC in Commercial BuildingsDemand Response Test in Large Facilities13 National Conference on Building

  11. Adaptive powertrain control for plugin hybrid electric vehicles

    DOE Patents [OSTI]

    Kedar-Dongarkar, Gurunath; Weslati, Feisel

    2013-10-15T23:59:59.000Z

    A powertrain control system for a plugin hybrid electric vehicle. The system comprises an adaptive charge sustaining controller; at least one internal data source connected to the adaptive charge sustaining controller; and a memory connected to the adaptive charge sustaining controller for storing data generated by the at least one internal data source. The adaptive charge sustaining controller is operable to select an operating mode of the vehicle's powertrain along a given route based on programming generated from data stored in the memory associated with that route. Further described is a method of adaptively controlling operation of a plugin hybrid electric vehicle powertrain comprising identifying a route being traveled, activating stored adaptive charge sustaining mode programming for the identified route and controlling operation of the powertrain along the identified route by selecting from a plurality of operational modes based on the stored adaptive charge sustaining mode programming.

  12. CRA Comments & Responses

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    - High-Level Liquid Waste (51105) 11 Response to CRA Comments (92005) Enclosure 1 - Computer Code VerificationTesting (92005) Inventory and Performance Assessment Reports...

  13. GADRAS Detector Response Function.

    SciTech Connect (OSTI)

    Mitchell, Dean J.; Harding, Lee; Thoreson, Gregory G; Horne, Steven M.

    2014-11-01T23:59:59.000Z

    The Gamma Detector Response and Analysis Software (GADRAS) applies a Detector Response Function (DRF) to compute the output of gamma-ray and neutron detectors when they are exposed to radiation sources. The DRF is fundamental to the ability to perform forward calculations (i.e., computation of the response of a detector to a known source), as well as the ability to analyze spectra to deduce the types and quantities of radioactive material to which the detectors are exposed. This document describes how gamma-ray spectra are computed and the significance of response function parameters that define characteristics of particular detectors.

  14. Climate Change Response

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    the Interior Climate Change Response "From the Everglades to the Great Lakes to Alaska and everywhere in between, climate change is a leading threat to natural and cultural...

  15. Demand Response In California

    Broader source: Energy.gov [DOE]

    Presentation covers the demand response in California and is given at the FUPWG 2006 Fall meeting, held on November 1-2, 2006 in San Francisco, California.

  16. Mechanisms of transcriptional activation of estrogen responsive genes in breast cancer cells 

    E-Print Network [OSTI]

    Chen, Chien-Cheng

    2009-06-02T23:59:59.000Z

    Estrogen receptor (ER) acts as a ligand-activated transcription factor that regulates the expression of genes. The genomic mechanisms of ER action include ligand-induced dimerization of ER which binds estrogen responsive elements (EREs...

  17. Mechanisms of transcriptional activation of estrogen responsive genes in breast cancer cells

    E-Print Network [OSTI]

    Chen, Chien-Cheng

    2009-06-02T23:59:59.000Z

    Estrogen receptor (ER) acts as a ligand-activated transcription factor that regulates the expression of genes. The genomic mechanisms of ER action include ligand-induced dimerization of ER which binds estrogen responsive elements (EREs...

  18. Method for removing tilt control in adaptive optics systems

    DOE Patents [OSTI]

    Salmon, Joseph Thaddeus (Livermore, CA)

    1998-01-01T23:59:59.000Z

    A new adaptive optics system and method of operation, whereby the method removes tilt control, and includes the steps of using a steering mirror to steer a wavefront in the desired direction, for aiming an impinging aberrated light beam in the direction of a deformable mirror. The deformable mirror has its surface deformed selectively by means of a plurality of actuators, and compensates, at least partially, for existing aberrations in the light beam. The light beam is split into an output beam and a sample beam, and the sample beam is sampled using a wavefront sensor. The sampled signals are converted into corresponding electrical signals for driving a controller, which, in turn, drives the deformable mirror in a feedback loop in response to the sampled signals, for compensating for aberrations in the wavefront. To this purpose, a displacement error (gradient) of the wavefront is measured, and adjusted by a modified gain matrix, which satisfies the following equation: G'=(I-X(X.sup.T X).sup.-1 X.sup.T)G(I-A)

  19. Method for removing tilt control in adaptive optics systems

    DOE Patents [OSTI]

    Salmon, J.T.

    1998-04-28T23:59:59.000Z

    A new adaptive optics system and method of operation are disclosed, whereby the method removes tilt control, and includes the steps of using a steering mirror to steer a wavefront in the desired direction, for aiming an impinging aberrated light beam in the direction of a deformable mirror. The deformable mirror has its surface deformed selectively by means of a plurality of actuators, and compensates, at least partially, for existing aberrations in the light beam. The light beam is split into an output beam and a sample beam, and the sample beam is sampled using a wavefront sensor. The sampled signals are converted into corresponding electrical signals for driving a controller, which, in turn, drives the deformable mirror in a feedback loop in response to the sampled signals, for compensating for aberrations in the wavefront. To this purpose, a displacement error (gradient) of the wavefront is measured, and adjusted by a modified gain matrix, which satisfies the following equation: G{prime} = (I{minus}X(X{sup T} X){sup {minus}1}X{sup T})G(I{minus}A). 3 figs.

  20. Eastern Frequency Response Study

    SciTech Connect (OSTI)

    Miller, N.W.; Shao, M.; Pajic, S.; D'Aquila, R.

    2013-05-01T23:59:59.000Z

    This study was specifically designed to investigate the frequency response of the Eastern Interconnection that results from large loss-of-generation events of the type targeted by the North American Electric Reliability Corp. Standard BAL-003 Frequency Response and Frequency Bias Setting (NERC 2012a), under possible future system conditions with high levels of wind generation.

  1. Electrochemical Characterization of Escherichia coli Adaptive Response Protein AidB

    E-Print Network [OSTI]

    Hamill, Michael J.

    When exposed to known DNA-damaging alkylating agents, Escherichia coli cells increase production of four DNA repair enzymes: Ada, AlkA, AlkB, and AidB. The role of three enzymes (Ada, AlkA, and AlkB) in repairing DNA lesions ...

  2. Institutional perspectives on road pricing : essays on implementation, response, and adaptation

    E-Print Network [OSTI]

    Mahendra, Anjali, 1977-

    2008-01-01T23:59:59.000Z

    Road pricing involves charging road users a fee for the external social costs of using private vehicles. These costs typically remain unaccounted for in routine road transport operations and benefit-cost analyses. They ...

  3. Plant responses associated with adaptation to low nitrogen stresses in selected Cynodon cultivars

    E-Print Network [OSTI]

    Sifers, Samuel I.

    1986-01-01T23:59:59.000Z

    samples under each fertility rate. The sod plugs were transplanted as solid plugs into plastic pots 20 cm deep x 21 cm top diameter. Washed mortar sand, leached with distilled water, was used as the planting medium. The pH at the time of planting was 7...), which are practica1ly identical. The small percentage of nitrogen remaining in the plants probably represents refractory ti ssue ni tr ogen and woul d be unavai 1 able to sustain any future growth. No diseases were evident at the final observation...

  4. Geographic variation in phenotypic plasticity in response to dissolved oxygen in an African cichlid fish

    E-Print Network [OSTI]

    Nuismer, Scott L.

    Geographic variation in phenotypic plasticity in response to dissolved oxygen in an African cichlid variation in a population over a number of generations to result in a population that is locally adapted and plastic variation in gill and brain size among swamp (low oxygen; hypoxic) and river (normal oxygen

  5. Seismic Response Analysis of Different Buildings using Time-Invariant and Time-Variant Damping Coefficients

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Seismic Response Analysis of Different Buildings using Time- Invariant and Time- Variant Damping@obs.ujf-grenoble.fr Abstract Seismic signals are characterized by strong excitations, short durations, non-linearity and non has been introduced to help in adapting to the seismic signals where the amplitude is damped

  6. Identification and molecular characterization of novel genomic targets in oxidant-induced vascular injury

    E-Print Network [OSTI]

    Partridge, Charles Randal

    2007-04-25T23:59:59.000Z

    stress. This regulatory region contained two distinct cis acting elements involved in promoter inducibility. These elements were tentatively identified as NFKB and TIEG-1 binding sites and shown to be highly responsive to hydrogen peroxide and chemical...

  7. Dietary L-arginine supplementation reduces fat mass in diet-induced obese rats

    E-Print Network [OSTI]

    Jobgen, Wenjuan Shi

    2009-06-02T23:59:59.000Z

    is enhanced in response to mitochondrial biogenesis induced by transcription factors, such as nuclear respiration factor (NRF)-1, NRF-2, PPARa, and mitochondrial transcription factor A (mtTFA). PGC-1a upregulates the expression of these transcription...

  8. Adaptive Implicit Non-Equilibrium Radiation Diffusion

    SciTech Connect (OSTI)

    Philip, Bobby [ORNL; Wang, Zhen [ORNL; Berrill, Mark A [ORNL; Rodriguez Rodriguez, Manuel [ORNL; Pernice, Michael [Idaho National Laboratory (INL)

    2013-01-01T23:59:59.000Z

    We describe methods for accurate and efficient long term time integra- tion of non-equilibrium radiation diffusion systems: implicit time integration for effi- cient long term time integration of stiff multiphysics systems, local control theory based step size control to minimize the required global number of time steps while control- ling accuracy, dynamic 3D adaptive mesh refinement (AMR) to minimize memory and computational costs, Jacobian Free Newton-Krylov methods on AMR grids for efficient nonlinear solution, and optimal multilevel preconditioner components that provide level independent solver convergence.

  9. Adaptive schemes for incomplete quantum process tomography

    SciTech Connect (OSTI)

    Teo, Yong Siah [Centre for Quantum Technologies, National University of Singapore, Singapore 117543 (Singapore); NUS Graduate School for Integrative Sciences and Engineering, Singapore 117597 (Singapore); Englert, Berthold-Georg [Centre for Quantum Technologies, National University of Singapore, Singapore 117543 (Singapore); Department of Physics, National University of Singapore, Singapore 117542 (Singapore); Rehacek, Jaroslav; Hradil, Zdenek [Department of Optics, Palacky University, 17. listopadu 12, CZ-77146 Olomouc (Czech Republic)

    2011-12-15T23:59:59.000Z

    We propose an iterative algorithm for incomplete quantum process tomography with the help of quantum state estimation. The algorithm, which is based on the combined principles of maximum likelihood and maximum entropy, yields a unique estimator for an unknown quantum process when one has less than a complete set of linearly independent measurement data to specify the quantum process uniquely. We apply this iterative algorithm adaptively in various situations and so optimize the amount of resources required to estimate a quantum process with incomplete data.

  10. Adaptive Materials Inc | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are beingZealand Jump to:Ezfeedflag JumpID-fTriWildcat 1AMEE Jump to:Ohio: Energy955°, -89.7755338° ShowAdaptive

  11. WeADAPT | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directedAnnualProperty Edit withTianlin BaxinUmweltVillageGraph HomeWaranaWater PowerWaverly MunicipalWeADAPT

  12. African Adaptation Programme | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directedAnnual Siteof Energy 2,AUDITCaliforniaWeifangwiki HomeASNAddGlobeJumpAdaptations Programme Name

  13. Cross-Scale Responses of Biodiversity to Hurricane and

    E-Print Network [OSTI]

    Willig, Michael

    Cross-Scale Responses of Biodiversity to Hurricane and Anthropogenic Disturbance in a Tropical and Georges, as well as by patterns of historic land use. Hurricane-induced changes in spatial organization changed after the hurricanes and were significantly different between Hurricanes Hugo and Georges. Alpha

  14. Adapter plate assembly for adjustable mounting of objects

    DOE Patents [OSTI]

    Blackburn, R.S.

    1986-05-02T23:59:59.000Z

    An adapter plate and two locking discs are together affixed to an optic table with machine screws or bolts threaded into a fixed array of internally threaded holes provided in the table surface. The adapter plate preferably has two, and preferably parallel, elongated locating slots each freely receiving a portion of one of the locking discs for secure affixation of the adapter plate to the optic table. A plurality of threaded apertures provided in the adapter plate are available to attach optical mounts or other devices onto the adapter plate in an orientation not limited by the disposition of the array of threaded holes in the table surface. An axially aligned but radially offset hole through each locking disc receives a screw that tightens onto the table, such that prior to tightening of the screw the locking disc may rotate and translate within each locating slot of the adapter plate for maximum flexibility of the orientation thereof.

  15. Adapter plate assembly for adjustable mounting of objects

    DOE Patents [OSTI]

    Blackburn, Robert S. (Albuquerque, NM)

    1987-01-01T23:59:59.000Z

    An adapter plate and two locking discs are together affixed to an optic table with machine screws or bolts threaded into a fixed array of internally threaded holes provided in the table surface. The adapter plate preferably has two, and preferably parallel, elongated locating slots each freely receiving a portion of one of the locking discs for secure affixation of the adapter plate to the optic table. A plurality of threaded apertures provided in the adapter plate are available to attach optical mounts or other devices onto the adapter plate in an orientation not limited by the disposition of the array of threaded holes in the table surface. An axially aligned but radially offset hole through each locking disc receives a screw that tightens onto the table, such that prior to tightening of the screw the locking disc may rotate and translate within each locating slot of the adapter plate for maximum flexibility of the orientation thereof.

  16. The Adaptive Optics Lucky Imager: combining adaptive optics and lucky imaging

    E-Print Network [OSTI]

    Crass, Jonathan

    2014-07-01T23:59:59.000Z

    , in particular the adaptive optics system and a new type of wavefront sensor, the non-linear curvature wavefront sensor (nlCWFS), being used within the instrument. The development of the nlCWFS has been the focus of my work, bringing the technique from a...

  17. Supporting User Adaptation in Adaptive Hypermedia Applications Hongjing Wu, GeertJan Houben, Paul De Bra

    E-Print Network [OSTI]

    De Bra, Paul

    applications, named AHAM (for Adaptive Hypermedia Application Model) [DHW99]. In AHAM knowledge is represented through hierarchies of large composite abstract concepts as well as small atomic ones. AHAM also divides. In this paper, we concentrate on the user modeling aspects of AHAM, but also describe how they relate

  18. Supporting User Adaptation in Adaptive Hypermedia Applications Hongjing Wu, Geert-Jan Houben, Paul De Bra

    E-Print Network [OSTI]

    Houben, Geert-Jan

    applications, named AHAM (for Adaptive Hypermedia Application Model) [DHW99]. In AHAM knowledge is represented through hierarchies of large composite abstract concepts as well as small atomic ones. AHAM also divides. In this paper, we concentrate on the user modeling aspects of AHAM, but also describe how they relate

  19. Error Correction, Sensory Prediction, and Adaptation

    E-Print Network [OSTI]

    in the response of our proprioceptive neurons. The transmission lines that connect a robot's motors and sensors to issue commands in microseconds. In contrast, our transmission lines (axons) move information slower than

  20. CitiSense Adaptive Services for Community-Driven Behavioral and Environmental Monitoring to Induce

    E-Print Network [OSTI]

    Simunic, Tajana

    times nor at equal risk for asthma or other harmful consequences of air pollution. What if everyday RI³FLWL]HQ LQIUDVWUXFWXUH´ for the monitoring of pollution and environmental conditions that users by users, data about pollutants such as ozone and carbon monoxide is collected and used to provide real

  1. The analysis of convergence for four adaptive filtering algorithms

    E-Print Network [OSTI]

    Sohn, Won

    1990-01-01T23:59:59.000Z

    . The Relation Between AREs of Estimators and Detectors . 29 IV THE ANALYSIS OF THE LMS AI, GORITHM AND ITS FAMILY 31 V A. General Case B. Same Steady-state MSE SIMULATION OF ADAPTIVE FILTERING ALGORITHMS . 42 VI A. Simulation Model 1. Adaptive... Equalization 2. System Identification B. Learning Curves of Adaptive Filtering Algorithms 1. Same Steady-state MSE . 2. Same Speed of Convergence. . . . . . . . . . C. Simulation Results for the ARE 1. Same Steady-state MSE . . 2. Same Speed...

  2. Frequency Response Analysis Tool

    SciTech Connect (OSTI)

    Etingov, Pavel V.; Kosterev, Dmitry; Dai, T.

    2014-12-31T23:59:59.000Z

    Frequency response has received a lot of attention in recent years at the national level, which culminated in the development and approval of North American Electricity Reliability Corporation (NERC) BAL-003-1 Frequency Response and Frequency Bias Setting Reliability Standard. This report is prepared to describe the details of the work conducted by Pacific Northwest National Laboratory (PNNL) in collaboration with the Bonneville Power Administration and Western Electricity Coordinating Council (WECC) Joint Synchronized Information Subcommittee (JSIS) to develop a frequency response analysis tool (FRAT). The document provides the details on the methodology and main features of the FRAT. The tool manages the database of under-frequency events and calculates the frequency response baseline. Frequency response calculations are consistent with frequency response measure (FRM) in NERC BAL-003-1 for an interconnection and balancing authority. The FRAT can use both phasor measurement unit (PMU) data, where available, and supervisory control and data acquisition (SCADA) data. The tool is also capable of automatically generating NERC Frequency Response Survey (FRS) forms required by BAL-003-1 Standard.

  3. adaptive localization regions: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    22 23 24 25 Next Page Last Page Topic Index 1 Developing regional and local scenarios for climate change mitigation and adaptation Geosciences Websites Summary: Developing regional...

  4. adapted mucoid strains: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    proposed by Francfort and Marigo in 19 Cremers, Daniel 2 Adaptation CiteSeer Summary: Climate change is expected to bring potentially significant changes to Washington States...

  5. adaptive supply survival: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Pike, Ivy L. 2003-12-01 8 Edinburgh Research Explorer Partial costs of global climate change adaptation for the supply Biology and Medicine Websites Summary: Edinburgh Research...

  6. affects adaptive allocation: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of water allocation institutions on societys adaptability to prospective climate change. Such institutions include basic systems of water law, specific statutes, systems of...

  7. adaptive slot allocation: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of water allocation institutions on societys adaptability to prospective climate change. Such institutions include basic systems of water law, specific statutes, systems of...

  8. Adaptive Control to Improve Low Temperature Diesel Engine Combustion...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Control to Improve Low Temperature Diesel Engine Combustion Adaptive Control to Improve Low Temperature Diesel Engine Combustion Presentation given at DEER 2006, August 20-24,...

  9. adaptive control strategies: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    using any finite number of channel evaluations. Aram W. Harrow; Avinatan Hassidim; Debbie W. Leung; John Watrous 2009-09-01 12 CONTRIBUTED Adaptive Stochastic Control Energy...

  10. Mean and covariance matrix adaptive estimation for a weakly ...

    E-Print Network [OSTI]

    2011-01-25T23:59:59.000Z

    AMS 2000 subject classification: Primary: 62G05, 62M10; Secondary: 90C15. Key words and phrases: Adaptive estimation, weakly stationary process, stochastic ...

  11. adaptive finite element: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    properties and performance of the adaptive finite element approach to the design of nano-photonic components. Central issues are the construction of vectorial finite elements...

  12. adaptive finite elements: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    properties and performance of the adaptive finite element approach to the design of nano-photonic components. Central issues are the construction of vectorial finite elements...

  13. adaptation biological: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    1, 3, 4. Here Averof, Michalis 39 Master's theses projects: Adaptations to a warming Baltic Sea We look for candidates interested in aquatic ecology to work on projects...

  14. adapter protein sly1: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    to their own needs. This is achieved by enabling users... Heeren, Bastiaan 2010-01-01 157 Baltic Ecosystem Adaptive Management Environmental Sciences and Ecology Websites Summary:...

  15. adaptation taenkbara konsekvenser: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Smart Grid holds the promise of providing the autonomous intelligence of distributed generation and storage within the Smart Grid. KEYWORDS | Adaptive stochastic control (ASC...

  16. adaptive distributed control: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Smart Grid holds the promise of providing the autonomous intelligence of distributed generation and storage within the Smart Grid. KEYWORDS | Adaptive stochastic control (ASC...

  17. adapting balanced scorecard: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Brusilovsky School of Information and the same links to all - Stores - Museums - Courses - News sites Adaptive Web-based systems and sites Brusilovsky, Peter 237...

  18. How to Integrate Climate Change Adaptation into National-Level...

    Open Energy Info (EERE)

    Integrate Climate Change Adaptation into National-Level Policy and Planning in the Water Sector Jump to: navigation, search Tool Summary LAUNCH TOOL Name: How to Integrate Climate...

  19. adaptive composite grid: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    space and ti... Thornburg, Jonathan 2009-01-01 10 Adaptive Rate Stream Processing for Smart Grid Applications on Clouds Computer Technologies and Information Sciences Websites...

  20. adaptive grid generation: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    space and ti... Thornburg, Jonathan 2009-01-01 12 Adaptive Rate Stream Processing for Smart Grid Applications on Clouds Computer Technologies and Information Sciences Websites...

  1. Adaptive finite element method for eddy current problems

    E-Print Network [OSTI]

    Adaptive finite element method for eddy current problems. In this chapter we shall discuss Maxwell's equations at very low frequencies. We also refer to [bo98 ...

  2. astec code adaptability: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Marom 1997-07-14 2 Adaptive decoding for dense and sparse evaluationinterpolation codes Computer Technologies and Information Sciences Websites Summary: with errors Decoding...

  3. adaptive chemistry dac: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Tool Needs for Faster Mainstream Acceptance of 3D Lim, Sung Kyu 5 Ethical Conduct in Science and Engineering Adapted from Chemistry-Biology Interface Program Ethics Materials...

  4. adaptive aberration correction: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    2 Accommodation with higher-order monochromatic aberrations corrected with adaptive optics Biology and Medicine Websites Summary: . However, the eye suffers from higher-order...

  5. adaptive signal model: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Michael Richard 1990-11-13 2 UNCORRECTED 2 Stochastic adaptive control model for traffic signal systems Environmental Sciences and Ecology Websites Summary: process. The model...

  6. adaptive hifu noise: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Noise Engineering Websites Summary: An Adaptive Noise Removal Approach for Restoration of Digital Images Corrupted by Multimodal Noise process compromises the performance of the...

  7. acquired behaviour adaptations: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and their envi- ronment affect each other; and representation of full life cycles. Ecology has contributed to agent-based modelling Boone, Randall B. 22 Adaptive Modelling...

  8. adaptive social immunity: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    to climate risk in the coffee sector of Chiapas, Mexico Environmental Sciences and Ecology Websites Summary: Social identity, perception and motivation in adaptation to...

  9. adaptive model predictive: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Mining CERN Preprints Summary: Nullifying the servo bandwidth errors improves the strehl ratio by a substantial quantity in adaptive optics systems. An effective method for...

  10. adaptive control scheme: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    systems concepts. Based Alpcan, Tansu 5 Adaptive predictive lighting controllers for daylight artificial light integrated schemes. Open Access Theses and Dissertations Summary:...

  11. adapted phi29 motor: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    an adjustment in the tension felt by the transduction channels. It has been suggested that steady- state tension is regulated a mathematical model for an adaptation motor...

  12. adaptation project pay: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    is adapting Linux for use in enterprise-scale networking Michigan, University of 445 Siemens Global Studio Project: Experiences Adopting an Integrated GSD Infrastructure...

  13. adaptive antenna system: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    widely used in civil engineering to evaluate building's structural re-sistance to seismic events... Munoz, Freddy 2009-01-01 164 User Models for Adaptive Hypermedia and...

  14. adaptive nonparametric instrumental: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    both selects Faraway, Julian 27 Spanish Version of the Sport Satisfaction Instrument (SSI) Adapted to Physical Education CiteSeer Summary: The objective of this research was to...

  15. adaptive management tool: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    management as an alternative to traditional natural resource planning and management models. Adaptive management may provide BLM managers ... Brandenburg, Peter (Peter J.)...

  16. Central African Republic-National Adaptation Plan Global Support...

    Open Energy Info (EERE)

    manual, Publications, Workshop Website http:undp-alm.orgprojectsn Program Start 2013 Country Central African Republic Middle Africa References National Adaptation Plan...

  17. adaptive numerical methods: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Websites Summary: An adaptive numerical method for the Richards equation with root growth Olga Wilderotter and plant root growth is presented. It allows the calculation of the...

  18. activity trial adapt: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    addressed ways to reduce greenhouse gas emissions Acting on Climate Change effects on industry, agriculture, tourism, and other human activities. Develop and recommend adaptation...

  19. adaptive neural coding: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    examples and in an application to image compression. 1 Introduction The self Zachmann, Gabriel 42 Adaptive Control Using Combined Online and Background Learning Neural...

  20. adapted neural population: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    examples and in an application to image compression. 1 Introduction The self Zachmann, Gabriel 24 Adaptive Control Using Combined Online and Background Learning Neural...

  1. adaptive interferometer based: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    current hardware: the science camera, the wavefront sensor, and the adaptive secondary mirror. In preliminary testing, we have implemented an eye doctor'' grid search approach...

  2. adaptive human aware: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    they display afterwards. They also show significantly larger aftereffects than ... Roach, Louise 2007-01-01 15 An Adaptive Quality of Service Aware Middleware for Replicated...

  3. adaptations impaired oxidative: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    learning of phonetic consistency and generalized neural adaptation deficits in dyslexia MIT - DSpace Summary: Developmental dyslexia is a neurological condition that...

  4. Adaptive Injection Strategies (AIS) for Ultra-low Emissions Diesel...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Injection Strategies (AIS) for Ultra-low Emissions Diesel Engines Adaptive Injection Strategies (AIS) for Ultra-low Emissions Diesel Engines Presentation given at the 2007 Diesel...

  5. adaptive control design: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    deployment mechanism is also 497 DESIGNER INTEGRATION IN TRAINING CYCLES : IEEE LTSA MODEL ADAPTATION Computer Technologies and Information Sciences Websites Summary: . The...

  6. adapting cardiovascular training: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    (more) Brown, Allan 1991-01-01 217 DESIGNER INTEGRATION IN TRAINING CYCLES : IEEE LTSA MODEL ADAPTATION Computer Technologies and Information Sciences Websites Summary: . The...

  7. adaptive design clinical: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    deployment mechanism is also 146 DESIGNER INTEGRATION IN TRAINING CYCLES : IEEE LTSA MODEL ADAPTATION Computer Technologies and Information Sciences Websites Summary: . The...

  8. Applying Climate Information for Adaptation Decision-Making:...

    Open Energy Info (EERE)

    Applying Climate Information for Adaptation Decision-Making: A Guidance and Resource Document Jump to: navigation, search Tool Summary LAUNCH TOOL Name: Applying Climate...

  9. Financing Climate Adaptation and Mitigation in Rural Areas of...

    Open Energy Info (EERE)

    Countries Jump to: navigation, search Tool Summary LAUNCH TOOL Name: Financing Climate Adaptation and Mitigation in Rural Areas of Developing Countries AgencyCompany...

  10. Quantitative Adaptation Analytics for Assessing Dynamic Systems of Systems.

    SciTech Connect (OSTI)

    Gauthier, John H.; Miner, Nadine E.; Wilson, Michael L.; Le, Hai D.; Kao, Gio K; Melander, Darryl J.; Longsine, Dennis Earl [Sandia National Laboratories, Unknown, Unknown; Vander Meer, Robert Charles,

    2015-01-01T23:59:59.000Z

    Our society is increasingly reliant on systems and interoperating collections of systems, known as systems of systems (SoS). These SoS are often subject to changing missions (e.g., nation- building, arms-control treaties), threats (e.g., asymmetric warfare, terrorism), natural environments (e.g., climate, weather, natural disasters) and budgets. How well can SoS adapt to these types of dynamic conditions? This report details the results of a three year Laboratory Directed Research and Development (LDRD) project aimed at developing metrics and methodologies for quantifying the adaptability of systems and SoS. Work products include: derivation of a set of adaptability metrics, a method for combining the metrics into a system of systems adaptability index (SoSAI) used to compare adaptability of SoS designs, development of a prototype dynamic SoS (proto-dSoS) simulation environment which provides the ability to investigate the validity of the adaptability metric set, and two test cases that evaluate the usefulness of a subset of the adaptability metrics and SoSAI for distinguishing good from poor adaptability in a SoS. Intellectual property results include three patents pending: A Method For Quantifying Relative System Adaptability, Method for Evaluating System Performance, and A Method for Determining Systems Re-Tasking.

  11. adaptive numerical dissipative: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    linear function while the frictional dissipation rate is a cubic power of surface wind speed, the dissipation rate is generally smaller Wang, Yuqing 7 An Adaptive Numerical...

  12. adaptive phase tracking: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    de 107 IEEE TRANSACTIONS ON CIRCUITS AND SYSTEMS FOR VIDEO TECHNOLOGY, VOL. 9, NO. 7, OCTOBER 1999 1025 Adaptive Motion Tracking Block Matching Algorithms for Video Coding...

  13. ADAPTIVE AND ROBUST TECHNIQUES (ART) FOR THERMOACOUSTIC TOMOGRAPHY

    E-Print Network [OSTI]

    Xie, Yao

    ADAPTIVE AND ROBUST TECHNIQUES (ART) FOR THERMOACOUSTIC TOMOGRAPHY By YAO XIE A DISSERTATION.1 Thermoacoustic Tomography . . . . . . . . . . . . . . . . . . . . . 1 1.2 Image Reconstruction Algorithms for TAT

  14. adaptive harvest management: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Workload. Martin, W. Powley, R. Horman, and P. Bird, "Workload Adaptation in Autonomic DBMs", Proceedings of CASCON 2006, Toronto, Canada, October 16 - 19, 2006, pp 161 - 173"...

  15. adaptive antioxidant methionine: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Departments of *Ecology for review July 26, 2005) Adaptive radiation is defined as the evolution of ecological and phenotypic diversity within a rapidly multiplying lineage....

  16. Development based climate change adaptation and mitigation-conceptual...

    Open Energy Info (EERE)

    countries AgencyCompany Organization: Lawrence Berkeley National Laboratory (LBNL) Sector: Climate, Energy, Land, Water Topics: Adaptation, Co-benefits assessment, -...

  17. adaptive regression modeling: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Information Sciences Websites Summary: Kernel smoothing is a widely used non-parametric pattern recognition technique. By nature, it suffers, adaptive metric, cross-vali-...

  18. adaptive learning environments: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    In Saarbrucken we are developing the web-based, user-adaptive, interactive learning environment Active 69 Medium-based design: Extending a medium to create and exploratory...

  19. Characterizing Uncertainty for Regional Climate Change Mitigation and Adaptation Decisions

    SciTech Connect (OSTI)

    Unwin, Stephen D.; Moss, Richard H.; Rice, Jennie S.; Scott, Michael J.

    2011-09-30T23:59:59.000Z

    This white paper describes the results of new research to develop an uncertainty characterization process to help address the challenges of regional climate change mitigation and adaptation decisions.

  20. adaptive optics parameters: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    projects for large telescopes demand a proper knowledge of atmospheric turbulence to design efficient adaptive optics systems in order to reach large Strehl ratios. However, the...

  1. Adaptation to Climate Variability and Change: A Guidance Manual...

    Open Energy Info (EERE)

    to Climate Variability and Change: A Guidance Manual for Development Planning Jump to: navigation, search Tool Summary LAUNCH TOOL Name: Adaptation to Climate Variability and...

  2. Economic Evaluation of Climate Change Adaptation Projects: Approaches...

    Open Energy Info (EERE)

    of Climate Change Adaptation Projects: Approaches for the Agricultural Sector and Beyond Jump to: navigation, search Tool Summary LAUNCH TOOL Name: Economic Evaluation of Climate...

  3. adaptive feedback control: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    45 Adaptive Management of Irrigation with Feedback Control to Avoid Groundwater Pollution by Nitrate University of California eScholarship Repository Summary: cmhr) Soil...

  4. Adaptive Injection Strategies (AIS) for Ultra-low Emissions Diesel...

    Broader source: Energy.gov (indexed) [DOE]

    * Motivation and background * Adaptive Injection Strategy (AIS) * Simulation and optimization - Two-Stage Combustion (TSC -- HCCI + Diffusion combustion) optimization using AIS...

  5. adaptive genetic algorithm: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    a xed crossover Emmerich, Michael 2 Self-Adaptive Genetic Algorithm for Constrained Optimization. Open Access Theses and Dissertations Summary: ??This study proposes a...

  6. adaptive sampling strategy: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ADAPTATION STRATEGIES FOR SAN LUIS OBISPO COUNTY: Preliminary Climate Change Climate Change Center JULY 2012 CEC5002012054 Prepared for: California Energy Commission...

  7. adapted seawater microbiota: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    the anticancer immune effects Cai, Long 8 Adaptation CiteSeer Summary: Climate change is expected to bring potentially significant changes to Washington States natural,...

  8. Adaptive Stack with Subdivided Cells for Improved Stability,...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    with Subdivided Cells for Improved Stability, Reliability, and Durability under Automotive Load Cycle Adaptive Stack with Subdivided Cells for Improved Stability, Reliability,...

  9. Seismic Technology Adapted to Analyzing and Developing Geothermal...

    Broader source: Energy.gov (indexed) [DOE]

    Program 2010 Peer Review Seismic Technology Adapted to Analyzing and Developing Geothermal Systems Below Surface-Exposed High-Velocity Rocks Principal Investigator: Bob A. Hardage...

  10. Apollo: Adaptive power optimization and Control for the land Warrior

    E-Print Network [OSTI]

    Pedram, Massoud

    Apollo: Adaptive power optimization and Control for the land Warrior Massoud Pedram Dept. of EE management Architecture organization techniquesArchitecture organization techniques Apollo TestbedApollo

  11. Intelligent Software Agents: Sensor Integration and Response

    SciTech Connect (OSTI)

    Kulesz, James J [ORNL; Lee, Ronald W [ORNL

    2013-01-01T23:59:59.000Z

    Abstract In a post Macondo world the buzzwords are Integrity Management and Incident Response Management. The twin processes are not new but the opportunity to link the two is novel. Intelligent software agents can be used with sensor networks in distributed and centralized computing systems to enhance real-time monitoring of system integrity as well as manage the follow-on incident response to changing, and potentially hazardous, environmental conditions. The software components are embedded at the sensor network nodes in surveillance systems used for monitoring unusual events. When an event occurs, the software agents establish a new concept of operation at the sensing node, post the event status to a blackboard for software agents at other nodes to see , and then react quickly and efficiently to monitor the scale of the event. The technology addresses a current challenge in sensor networks that prevents a rapid and efficient response when a sensor measurement indicates that an event has occurred. By using intelligent software agents - which can be stationary or mobile, interact socially, and adapt to changing situations - the technology offers features that are particularly important when systems need to adapt to active circumstances. For example, when a release is detected, the local software agent collaborates with other agents at the node to exercise the appropriate operation, such as: targeted detection, increased detection frequency, decreased detection frequency for other non-alarming sensors, and determination of environmental conditions so that adjacent nodes can be informed that an event is occurring and when it will arrive. The software agents at the nodes can also post the data in a targeted manner, so that agents at other nodes and the command center can exercise appropriate operations to recalibrate the overall sensor network and associated intelligence systems. The paper describes the concepts and provides examples of real-world implementations including the Threat Detection and Analysis System (TDAS) at the International Port of Memphis and the Biological Warning and Incident Characterization System (BWIC) Environmental Monitoring (EM) Component. Technologies developed for these 24/7 operational systems have applications for improved real-time system integrity awareness as well as provide incident response (as needed) for production and field applications.

  12. The design of energy-responsive commercial buildings

    SciTech Connect (OSTI)

    Ternoey, S.; Bickle, L.; Robbins, C.; Busch, R.; Mc Cord, K.

    1985-01-01T23:59:59.000Z

    This book is a practical guide for building designers who want to reduce the nonrenewable energy needs of commercial and institutional buildings. The book presents, compares, and interprets the most current information on the principles, advantages, and disadvantages of many energy-related design alternatives. Topics considered include reviewing and interpreting our collective learning experience, the range of possible solutions, energy-responsive climate-rejecting buildings, energy-responsive climate-adapted buildings, the range of possible design approaches, a framework for design, a recommended design approach, applying the recommended design approach: examples, the financial value of energy-responsive design, building energy analysis during early design stages, and component energy analysis during early design stages.

  13. Rollable multicolor display using electrically induced blueshift of a cholesteric reactive mesogen mixture

    E-Print Network [OSTI]

    Wu, Shin-Tson

    Rollable multicolor display using electrically induced blueshift of a cholesteric reactive mesogen September 2006 Electrically controllable blueshift of the reflection band in a planar cholesteric reactive mesogen cell is observed. The responsible mechanism is electric-field-induced Helfrich deformation J. Chem

  14. Pollution-induced behavioural effects in the brown bullhead (Ameiurus nebulosus)

    E-Print Network [OSTI]

    Neff, Bryan D.

    Pollution-induced behavioural effects in the brown bullhead (Ameiurus nebulosus) Ross D. Breckels on biodiversity. Thus, it is important to understand the nature of pollution- induced change in aquatic ecosystems. We show that brown bullheads (Ameiurus nebulosus) may have evolved in response to chronic pollution

  15. JNK signaling in neomycin-induced vestibular hair cell death Kazuma Sugahara1, 2

    E-Print Network [OSTI]

    Rubel, Edwin

    JNK signaling in neomycin-induced vestibular hair cell death Kazuma Sugahara1, 2 , Edwin W Rubel1;Abstract Mechanosensory hair cells are susceptible to apoptotic death in response to exposure to ototoxic signaling pathway can prevent aminoglycoside-induced death of cochlear and vestibular sensory hair cells. We

  16. Accident Response Group

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1991-09-20T23:59:59.000Z

    To establish Department of Energy (DOE) policy for DOE response to accidents and significant incidents involving nuclear weapons or nuclear weapon components. Cancels DOE O 5530.1. Canceled by DOE O 153.1.

  17. Adaptive SSL: Design, Implementation and Overhead Analysis submission for Work-in-Progress/Application Paper track.

    E-Print Network [OSTI]

    Newcastle upon Tyne, University of

    Adaptive SSL: Design, Implementation and Overhead Analysis submission for Work an adaptation controller for SSL (Secure Socket Layer), called Adaptive SSL. 1 Introduction Applications adaptation of the Secure Socket Layer (SSL) protocol [3]. Adaptive SSL (ASSL) aims to provide appropriate se

  18. Structural response of nematic liquid crystals to weak transient shear flows

    E-Print Network [OSTI]

    Mather, Patrick T.

    dynamic director response of nematics to oscillatory shearand step shear strain. In oscillation, the ratioStructural response of nematic liquid crystals to weak transient shear flows P. T. Matherajpb is presentedfor director field relaxationfollowing distortion induced by a step strain. Step strainexperimentson 5

  19. Physiologic Responses to Acupuncture Point Stimulation: A Pilot Study to Evaluate Methods and

    E-Print Network [OSTI]

    , and electrodermal response (EDR) were measured along with the times of needle insertion, interim needle stimulation and electrodermal responses (EDR) [1]­[12]. The results of these individual studies, in which commonly used APs] determined that activation of an auricular AP decreased a stimulus-induced EDR while Wang and Cain [13

  20. Adaptive model training system and method

    DOE Patents [OSTI]

    Bickford, Randall L; Palnitkar, Rahul M; Lee, Vo

    2014-04-15T23:59:59.000Z

    An adaptive model training system and method for filtering asset operating data values acquired from a monitored asset for selectively choosing asset operating data values that meet at least one predefined criterion of good data quality while rejecting asset operating data values that fail to meet at least the one predefined criterion of good data quality; and recalibrating a previously trained or calibrated model having a learned scope of normal operation of the asset by utilizing the asset operating data values that meet at least the one predefined criterion of good data quality for adjusting the learned scope of normal operation of the asset for defining a recalibrated model having the adjusted learned scope of normal operation of the asset.

  1. Adaptive model training system and method

    DOE Patents [OSTI]

    Bickford, Randall L; Palnitkar, Rahul M

    2014-11-18T23:59:59.000Z

    An adaptive model training system and method for filtering asset operating data values acquired from a monitored asset for selectively choosing asset operating data values that meet at least one predefined criterion of good data quality while rejecting asset operating data values that fail to meet at least the one predefined criterion of good data quality; and recalibrating a previously trained or calibrated model having a learned scope of normal operation of the asset by utilizing the asset operating data values that meet at least the one predefined criterion of good data quality for adjusting the learned scope of normal operation of the asset for defining a recalibrated model having the adjusted learned scope of normal operation of the asset.

  2. Adaptable radiation monitoring system and method

    DOE Patents [OSTI]

    Archer, Daniel E. (Livermore, CA); Beauchamp, Brock R. (San Ramon, CA); Mauger, G. Joseph (Livermore, CA); Nelson, Karl E. (Livermore, CA); Mercer, Michael B. (Manteca, CA); Pletcher, David C. (Sacramento, CA); Riot, Vincent J. (Berkeley, CA); Schek, James L. (Tracy, CA); Knapp, David A. (Livermore, CA)

    2006-06-20T23:59:59.000Z

    A portable radioactive-material detection system capable of detecting radioactive sources moving at high speeds. The system has at least one radiation detector capable of detecting gamma-radiation and coupled to an MCA capable of collecting spectral data in very small time bins of less than about 150 msec. A computer processor is connected to the MCA for determining from the spectral data if a triggering event has occurred. Spectral data is stored on a data storage device, and a power source supplies power to the detection system. Various configurations of the detection system may be adaptably arranged for various radiation detection scenarios. In a preferred embodiment, the computer processor operates as a server which receives spectral data from other networked detection systems, and communicates the collected data to a central data reporting system.

  3. Weitzenböck's Torsion, Fermi Coordinates and Adapted Frames

    E-Print Network [OSTI]

    Donato Bini; Bahram Mashhoon

    2015-04-19T23:59:59.000Z

    We study Weitzenb\\"ock's torsion and discuss its properties. Specifically, we calculate the measured components of Weitzenb\\"ock's torsion tensor for a frame field adapted to static observers in a Fermi normal coordinate system that we establish along the world line of an arbitrary accelerated observer in general relativity. A similar calculation is carried out in the standard Schwarzschild-like coordinates for static observers in the exterior Kerr spacetime; we then compare our results with the corresponding curvature components. Our work supports the contention that in the extended general relativistic framework involving both the Levi-Civita and Weitzenb\\"ock connections, curvature and torsion provide complementary representations of the gravitational field.

  4. Adaptively refined large eddy simulations of clusters

    E-Print Network [OSTI]

    Maier, A; Schmidt, W; Niemeyer, J C

    2009-01-01T23:59:59.000Z

    We present a numerical scheme for modelling unresolved turbulence in cosmological adaptive mesh refinement codes. As a first application, we study the evolution of turbulence in the intra-cluster medium and in the core of a galaxy cluster. Simulations with and without subgrid scale model are compared in detail. Since the flow in the ICM is subsonic, the global turbulent energy contribution at the unresolved length scales is smaller than 1% of the internal energy. We find that the production of turbulence is closely correlated with merger events occurring in the cluster environment, and its dissipation locally affects the cluster energy budget. Because of this additional source of dissipation, the core temperature is larger and the density is smaller in the presence of subgrid scale turbulence than in the standard adiabatic run, resulting in a higher entropy core value.

  5. Adapting MARSSIM for FUSRAP site closure.

    SciTech Connect (OSTI)

    Johnson, R.; Durham, L.; Rieman, C.; Hoover, R.

    2001-12-21T23:59:59.000Z

    The Multi-Agency Radiation Survey and Site Investigation Manual (MARSSIM) provides a coherent, technically defensible process for establishing that exposed surfaces satisfy site cleanup requirements. Unfortunately, many sites have complications that challenge a direct application of MARSSIM. Example complications include Record of Decision (ROD) requirements that are not MARSSIM-friendly, the potential for subsurface contamination, and incomplete characterization information. These types of complications are typically the rule, rather than the exception, for sites undergoing radiologically-driven remediation and closure. One such site is the Formerly Utilized Sites Remedial Action Program (FUSRAP) Linde site in Tonawanda, New York. Cleanup of the site is currently underway. The Linde site presented a number of challenges to designing and implementing a closure strategy consistent with MARSSIM. This paper discusses some of the closure issues confronted by the U.S. Army Corps of Engineers Buffalo District at the Linde site, and describes how MARSSIM protocols were adapted to address these issues.

  6. Adaptive vibration control using synchronous demodulation with machine tool controller motor commutation

    DOE Patents [OSTI]

    Hopkins, David James (Livermore, CA)

    2008-05-13T23:59:59.000Z

    A control system and method for actively reducing vibration in a spindle housing caused by unbalance forces on a rotating spindle, by measuring the force-induced spindle-housing motion, determining control signals based on synchronous demodulation, and provide compensation for the measured displacement to cancel or otherwise reduce or attenuate the vibration. In particular, the synchronous demodulation technique is performed to recover a measured spindle housing displacement signal related only to the rotation of a machine tool spindle, and consequently rejects measured displacement not related to spindle motion or synchronous to a cycle of revolution. Furthermore, the controller actuates at least one voice-coil (VC) motor, to cancel the original force-induced motion, and adapts the magnitude of voice coil signal until this measured displacement signal is brought to a null. In order to adjust the signal to a null, it must have the correct phase relative to the spindle angle. The feedback phase signal is used to adjust a common (to both outputs) commutation offset register (offset relative to spindle encoder angle) to force the feedback phase signal output to a null. Once both of these feedback signals are null, the system is compensating properly for the spindle-induced motion.

  7. 9 Towards Adaptive Management of Native Vegetation in Regional Landscapes

    E-Print Network [OSTI]

    Burgman, Mark

    management remains widely cited as the most logical and elegant frame- work for continuous improvement9 Towards Adaptive Management of Native Vegetation in Regional Landscapes David H Duncan1 of the `adaptive management' paradigm to natural resource man- agement, using regional management of native

  8. Particle Systems for Adaptive, Isotropic Meshing of CAD Models

    E-Print Network [OSTI]

    Utah, University of

    Particle Systems for Adaptive, Isotropic Meshing of CAD Models Jonathan R. Bronson, Joshua A adaptive triangular surface and tetrahedral volume meshes from CAD models. Input shapes are treated. These particles reach a good distribution by minimizing an energy computed in 3D world space, with movements

  9. Equivocal Blind Signatures and Adaptive UC-Security Aggelos Kiayias

    E-Print Network [OSTI]

    Equivocal Blind Signatures and Adaptive UC-Security Aggelos Kiayias Hong-Sheng Zhou April 12, 2007 Abstract We study the design of practical blind signatures in the universal composability (UC) setting against adaptive adversaries. We introduce a new property for blind signature schemes

  10. Adaptive Blind Signal Processing--Neural Network Approaches

    E-Print Network [OSTI]

    Vialatte, François

    Adaptive Blind Signal Processing--Neural Network Approaches SHUN-ICHI AMARI, FELLOW, IEEE are presented for the problem of adaptive blind signal processing, especially instantaneous blind separation and multichannel blind deconvolution/equalization of independent source signals. We dis- cuss recent developments

  11. Are three-dimensional spider webs defensive adaptations?

    E-Print Network [OSTI]

    Blackledge, Todd

    LETTER Are three-dimensional spider webs defensive adaptations? Todd A. Blackledge1 *, Jonathan A-mail: tab42@cornell.edu Abstract Spider webs result from complex behaviours that have evolved under many selective pressures. Webs have been primarily considered to be foraging adaptations, neglecting

  12. adapted fish chionodraco: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    adapted fish chionodraco First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 NEWS AND COMMENTARY Adaptive...

  13. ADAPTIVE FINITE ELEMENT FREQUENCY DOMAIN METHOD FOR EDDY CURRENT PROBLEMS

    E-Print Network [OSTI]

    Zheng, Weiying

    ADAPTIVE FINITE ELEMENT FREQUENCY DOMAIN METHOD FOR EDDY CURRENT PROBLEMS WEIYING ZHENG-harmonic eddy current problems in the case of three-dimensional isotropic and linear materials. We adopt. Time-harmonic Maxwell's equations, eddy current, adaptive finite element method, multiply connected

  14. adaptive optics experiment: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    adaptive optics experiment First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Adaptive Optical Transport...

  15. adaptive optics monitoring: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    adaptive optics monitoring First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Adaptive Optical Transport...

  16. adaptive optics demonstrator: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    adaptive optics demonstrator First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Adaptive optic...

  17. adaptive optics correction: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    adaptive optics correction First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Adaptive optic correction...

  18. adaptive optics optical: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    adaptive optics optical First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Adaptive Optical Transport...

  19. adaptive optics scanning: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    adaptive optics scanning First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Adaptive Scanning Optical...

  20. adaptive optics planet: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    adaptive optics planet First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 An Adaptive Optics Survey for...