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1

Information bias and lifetime mortality risks of radiation-induced cancer: Low LET radiation  

Science Conference Proceedings (OSTI)

Additive and multiplicative models of relative risk were used to measure the effect of cancer misclassification and DS86 random errors on lifetime risk projections in the Life Span Study (LSS) of Hiroshima and Nagasaki atomic bomb survivors. The true number of cancer deaths in each stratum of the cancer mortality cross-classification was estimated using sufficient statistics from the EM algorithm. Average survivor doses in the strata were corrected for DS86 random error ({sigma}=0.45) by use of reduction factors. Poisson regression was used to model the corrected and uncorrected mortality rates with risks in RERF Report 11 (Part 2) and the BEIR-V Report. Bias due to DS86 random error typically ranged from {minus}15% to {minus}30% for both sexes, and all sites and models. The total bias, including diagnostic misclassification, of excess risk of nonleukemia for exposure to 1 Sv from age 18 to 65 under the non-constant relative project model was {minus}37.1% for males and {minus}23.3% for females. Total excess risks of leukemia under the relative projection model were biased {minus}27.1% for males and {minus}43.4% for females. Thus, nonleukemia risks for 1 Sv from ages 18 to 65 (DRREF=2) increased from 1.91%/Sv to 2.68%/Sv among males and from 3.23%/Sv to 4.92%/Sv among females. Leukemia excess risk increased from 0.87%/Sv to 1.10/Sv among males and from 0.73%/Sv to 1.04/Sv among females. Bias was dependent on the gender, site, correction method, exposure profile and projection model considered. Future studies that use LSS data for US nuclear workers may be downwardly biased if lifetime risk projections are not adjusted for random and systematic errors.

Peterson, L.E.; Schull, W.J.; Davis, B.R. [Texas Univ., Houston, TX (United States). Health Science Center; Buffler, P.A. [California Univ., Berkeley, CA (United States). School of Public Health

1994-04-01T23:59:59.000Z

2

B Lifetime  

NLE Websites -- All DOE Office Websites (Extended Search)

B Lifetime Equation Back to Finding B Lifetime Project Contact: Thomas Jordan - jordant@fnal.gov Web Maintainer: qnet-webmaster@fnal.gov Last Update: June, 2001 http:...

3

B Lifetime  

NLE Websites -- All DOE Office Websites (Extended Search)

Lifetime Lifetime Lifetime is similar to half-life, which you may have studied in radioactivity. More details on lifetime. Lifetime is the average time between creation and decay of a particle, which cannot be predicted for an individual particle, so we use the average time. The lifetime is the time when e-1 (or 37%) of them have survived. Derivation of equation To simplify calculations, we will use only the information in a plane perpendicular (transverse) to the beams, that is, in the x-y plane. The lifetime of B mesons is t = d/v (since velocity = distance/time) The velocity can be determined from the momentum. However, we cannot use the usual equation p = mv These particles are moving at velocities close to the speed of light, c. Here the correct formula is (Do you find the usual formula for p if v is much smaller than c?)

4

Particle Lifetimes  

NLE Websites -- All DOE Office Websites (Extended Search)

Reviewing Particle Lifetimes Reviewing Particle Lifetimes The lifetimes of elementary particles are statistical in nature. In a given sample, one particle might decay immediately, another in 1 nanosecond, yet another after 10 milliseconds, and still another in 50 years. What we call the lifetime is the time it takes for a sample to decay so 1/e (~30%) of the sample is left; after 2 lifetimes, 1/e2 of the sample is left, and so on. Take, for example, a sample of cosmic ray muons produced in the upper atmosphere. These muons, when observed at (relative) rest in the laboratory, have a mean lifetime T. Now, since particle decay is statistical in nature, the number of undecayed particles after a given time is a negative exponential function: N(t) = No e-t/T where N(t) is the number of muons at time t, No is the initial number of

5

Forecast Technical Document Volume Increment  

E-Print Network (OSTI)

Forecast Technical Document Volume Increment Forecasts A document describing how volume increment is handled in the 2011 Production Forecast. Tom Jenkins Robert Matthews Ewan Mackie Lesley Halsall #12;PF2011 ­ Volume increment forecasts Background A volume increment forecast is a fundamental output of the forecast

6

B Lifetime  

NLE Websites -- All DOE Office Websites (Extended Search)

Search Extra Project Find B lifetime. Found info: Source 5 Project Contact: Thomas Jordan - jordant@fnal.gov Web Maintainer: qnet-webmaster@fnal.gov Last Update: January 10,...

7

Incremental Nanotechnology for Structural Materials  

Science Conference Proceedings (OSTI)

Presentation Title, Incremental Nanotechnology for Structural Materials. Author(s) , Enrique J. Lavernia. On-Site Speaker (Planned), Enrique J. Lavernia. Abstract ...

8

Data Assimilation Using Incremental Analysis Updates  

Science Conference Proceedings (OSTI)

The IAU (incremental analysis updating) process incorporates analysis increments into a model integration in a gradual manner. It does this by using analysis increments as constant forcings in a model's prognostic equations over a 6-h period ...

S. C. Bloom; L. L. Takacs; A. M. da Silva; D. Ledvina

1996-06-01T23:59:59.000Z

9

On the Relationship between Incremental Analysis Updating and Incremental Digital Filtering  

Science Conference Proceedings (OSTI)

Incremental analysis updating (IAU) refers to a method of smoothly inserting instantaneous analysis increments into a numerical model by spreading the increments over a time period. In this work, this method is shown to be identical to applying a ...

Saroja Polavarapu; Shuzhan Ren; Adam M. Clayton; David Sankey; Yves Rochon

2004-10-01T23:59:59.000Z

10

Concept formation using incremental Gaussian mixture models  

Science Conference Proceedings (OSTI)

This paper presents a new algorithm for incremental concept formation based on a Bayesian framework. The algorithm, called IGMM (for Incremental Gaussian Mixture Model), uses a probabilistic approach for modeling the environment, and so, it can rely ... Keywords: Bayesian methods, EM algorithm, clustering, concept formation, finite mixtures, incremental learning, unsupervised learning

Paulo Martins Engel; Milton Roberto Heinen

2010-11-01T23:59:59.000Z

11

Tax Incremental Financing (Connecticut) | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Incremental Financing (Connecticut) Incremental Financing (Connecticut) Tax Incremental Financing (Connecticut) < Back Eligibility Agricultural Commercial Construction Fed. Government Fuel Distributor General Public/Consumer Industrial Installer/Contractor Institutional Investor-Owned Utility Local Government Low-Income Residential Multi-Family Residential Municipal/Public Utility Nonprofit Residential Retail Supplier Rural Electric Cooperative Schools State/Provincial Govt Systems Integrator Transportation Tribal Government Utility Savings Category Alternative Fuel Vehicles Hydrogen & Fuel Cells Buying & Making Electricity Water Home Weatherization Solar Wind Program Info State Connecticut Program Type Bond Program Provider Connecticut Development Authority CDA provides Tax Incremental Financing for significant economic

12

Incremental validity of the Psychopathic Personality Inventory.  

E-Print Network (OSTI)

??The current study examined the incremental validity of the Psychopathic Personality Inventory-Revised in relation to the Psychological Inventory of Criminal Thinking Styles and Personality Assessment… (more)

McCoy, Katrina.

2011-01-01T23:59:59.000Z

13

SigmaLifetime  

NLE Websites -- All DOE Office Websites (Extended Search)

uncertainty relation Et h4 and their measured energy spread E. STUDENT LEARNING OBJECTIVES 1. Lifetime of moving particles is related to track length in a bubble...

14

Three-dimensional fluorescence lifetime tomography  

Science Conference Proceedings (OSTI)

Near-infrared fluorescence tomography using molecularly targeted lifetime-sensitive, fluorescent contrast agents have applications for early-stage cancer diagnostics. Yet, although the measurement of fluorescent lifetime imaging microscopy (FLIM) is extensively used in microscopy and spectroscopy applications, demonstration of fluorescence lifetime tomography for medical imaging is limited to two-dimensional studies. Herein, the feasibility of three-dimensional fluorescence-lifetime tomography on clinically relevant phantom volumes is established, using (i) a gain-modulated intensified charge coupled device (CCD) and modulated laser diode imaging system, (ii) two fluorescent contrast agents, e.g., Indocyanine green and 3-3'-Diethylthiatricarbocyanine iodide differing in their fluorescence lifetime by 0.62 ns, and (iii) a two stage approximate extended Kalman filter reconstruction algorithm. Fluorescence measurements of phase and amplitude were acquired on the phantom surface under different target to background fluorescence absorption (70:1, 100:1) and fluorescence lifetime (1:1, 2.1:1) contrasts at target depths of 1.4-2 cm. The Bayesian tomography algorithm was employed to obtain three-dimensional images of lifetime and absorption owing to the fluorophores.

Godavarty, Anuradha; Sevick-Muraca, Eva M.; Eppstein, Margaret J. [327 Votey Building, Department of Computer Science, University of Vermont, Burlington, Vermont 05405 (United States); 1011 Richardson Building, Photon Migration Laboratories, Texas A and M University, College Station, Texas 77843 (United States); 327 Votey Building, Department of Computer Science, University of Vermont, Burlington, Vermont 05405 (United States)

2005-04-01T23:59:59.000Z

15

Ralph Holman Lifetime Achievement Award  

Science Conference Proceedings (OSTI)

Significant lifetime and meritorious achievements in areas of interest to the Health and Nutrition Division of AOCS are recognized with the Ralph Holman Lifetime Achievement Award. Ralph Holman Lifetime Achievement Award Divisions achievement agri

16

Iterative and Incremental Development: A Brief History  

Science Conference Proceedings (OSTI)

Although many view iterative and incremental development as a modern practice, its application dates as far back as the mid-1950s. Prominent software-engineering thought leaders from each succeeding decade supported IID practices, and many large projects ...

Craig Larman; Victor R. Basili

2003-06-01T23:59:59.000Z

17

Exergy analysis of incremental sheet forming  

E-Print Network (OSTI)

Research in the last 15 years has led to die-less incremental forming processes that are close to realization in an industrial setup. Whereas many studies have been carried out with the intention of investigating technical ...

Dittrich, M. A.

18

An incremental learning algorithm based on the K-associated graph for non-stationary data classification  

Science Conference Proceedings (OSTI)

Non-stationary classification problems concern the changes on data distribution over a classifier lifetime. To face this problem, learning algorithms must conciliate essential, but difficult to gather, attributes like good classification performance, ... Keywords: Concept drift, Graph-based learning, Incremental learning, K-associated graph, Non-stationary classification, Purity measure

JoãO Roberto Bertini, Jr, Liang Zhao, Alneu A. Lopes

2013-10-01T23:59:59.000Z

19

Tax Increment Financing (Iowa) | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Iowa) Iowa) Tax Increment Financing (Iowa) < Back Eligibility Commercial Industrial Construction Municipal/Public Utility Residential Savings Category Alternative Fuel Vehicles Hydrogen & Fuel Cells Home Weatherization Water Buying & Making Electricity Solar Wind Program Info State Iowa Program Type Industry Recruitment/Support Property Tax Incentive Provider Iowa Economic Development Authority Tax Increment Financing allows city councils or county boards of supervisors to use the property taxes resulting from the increase in taxable valuation caused by the construction of new industrial or commercial facilities to provide economic development incentives to a business or industry. Tax Increment Financing may be used to offset the cost of public improvements and utilities that will serve the new private

20

Tax Increment Financing (Louisiana) | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Louisiana) Louisiana) Tax Increment Financing (Louisiana) < Back Eligibility Agricultural Commercial Construction Developer Fuel Distributor Industrial Installer/Contractor Low-Income Residential Multi-Family Residential Residential Retail Supplier Systems Integrator Transportation Savings Category Alternative Fuel Vehicles Hydrogen & Fuel Cells Buying & Making Electricity Water Home Weatherization Solar Wind Program Info State Louisiana Program Type Property Tax Incentive Sales Tax Incentive Louisiana law provides for two types of Tax Increment Financing mechanisms: (1) property tax, also known as ad valorem, and (2) sales tax. Either form may be utilized to enhance an economic development project. In these, it is assumed the project will create future increases in tax revenue above

Note: This page contains sample records for the topic "incremental lifetime cancer" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


21

Incremental tensor analysis: Theory and applications  

Science Conference Proceedings (OSTI)

How do we find patterns in author-keyword associations, evolving over time? Or in data cubes (tensors), with product-branchcustomer sales information? And more generally, how to summarize high-order data cubes (tensors)? How to incrementally ... Keywords: Tensor, multilinear algebra, stream mining

Jimeng Sun; Dacheng Tao; Spiros Papadimitriou; Philip S. Yu; Christos Faloutsos

2008-10-01T23:59:59.000Z

22

Alternative Fuels Data Center: Vehicle Incremental Cost Allocation  

Alternative Fuels and Advanced Vehicles Data Center (EERE)

Vehicle Incremental Vehicle Incremental Cost Allocation to someone by E-mail Share Alternative Fuels Data Center: Vehicle Incremental Cost Allocation on Facebook Tweet about Alternative Fuels Data Center: Vehicle Incremental Cost Allocation on Twitter Bookmark Alternative Fuels Data Center: Vehicle Incremental Cost Allocation on Google Bookmark Alternative Fuels Data Center: Vehicle Incremental Cost Allocation on Delicious Rank Alternative Fuels Data Center: Vehicle Incremental Cost Allocation on Digg Find More places to share Alternative Fuels Data Center: Vehicle Incremental Cost Allocation on AddThis.com... More in this section... Federal State Advanced Search All Laws & Incentives Sorted by Type Vehicle Incremental Cost Allocation The U.S. General Services Administration (GSA) must allocate the

23

B Lifetimes and Mixing  

SciTech Connect

The Tevatron experiments, CDF and D0, have produced a wealth of new B-physics results since the start of Run II in 2001. We've observed new B-hadrons, seen new effects, and increased many-fold the precision with which we know the properties of b-quark systems. In these proceedings, we will discuss two of the most fruitful areas in the Tevatron B-physics program: lifetimes and mixing. We'll examine the experimental issues driving these analyses, present a summary of the latest results, and discuss prospects for the future.

Evans, Harold G.; /Indiana U.

2009-05-01T23:59:59.000Z

24

Original article Root biomass and biomass increment in a beech  

E-Print Network (OSTI)

Original article Root biomass and biomass increment in a beech (Fagus sylvatica L.) stand in North ­ This study is part of a larger project aimed at quantifying the biomass and biomass increment been developed to estimate the biomass and biomass increment of coarse, small and fine roots of trees

Recanati, Catherine

25

Desjarlais received Lifetime Achievement Award  

NLE Websites -- All DOE Office Websites (Extended Search)

Andr Desjarlais received a Lifetime Achievement Award from the Polyisocyanurate Insulation Manufacturers Association (PIMA) during the group's 25th Anniversary celebration...

26

Incremental Scale Up of Isasmelt™ - The Key to Its Success  

Science Conference Proceedings (OSTI)

The ISASMELT™ top submerged lance (TSL) process is a good example of a metallurgical process that was developed using incremental scale up.

27

Incremental-like Bundle Methods with Application to Energy Planning  

E-Print Network (OSTI)

Nov 18, 2008 ... Incremental-like Bundle Methods with Application to Energy Planning. Grégory Emiel (gemiel ***at*** impa.br) Claudia Sagastizábal (sagastiz ...

28

Runtime verification of object lifetime specifications  

E-Print Network (OSTI)

This thesis reports on the implementation of a runtime verification system for object lifetime specifications. This system is used to explore and evaluate the expressiveness object lifetime specifications. Object lifetime ...

Benjamin, Zev (Zev A.)

2009-01-01T23:59:59.000Z

29

Incremental spectral clustering by efficiently updating the eigen-system  

Science Conference Proceedings (OSTI)

In recent years, the spectral clustering method has gained attentions because of its superior performance. To the best of our knowledge, the existing spectral clustering algorithms cannot incrementally update the clustering results given a small change ... Keywords: Graph, Incidence vector/matrix, Incremental clustering, Spectral clustering, Web-blogs

Huazhong Ning; Wei Xu; Yun Chi; Yihong Gong; Thomas S. Huang

2010-01-01T23:59:59.000Z

30

Efficient Algorithms for Incremental Update of Frequent Sequences  

Science Conference Proceedings (OSTI)

Most of the works proposed so far on mining frequent sequences assume that the underlying database is static. However, in real life, the database is modified from time to time. This paper studies the problem of incremental update of frequent sequences ... Keywords: data mining, incremental update, sequence

Minghua Zhang; Ben Kao; David Wai-Lok Cheung; Chi Lap Yip

2002-05-01T23:59:59.000Z

31

CITOM: An incremental construction of multilingual topic maps  

Science Conference Proceedings (OSTI)

This paper proposes the CITOM approach for an incremental construction of multilingual Topic Maps. Our main goal is to facilitate user's navigation across documents available in different languages. Our approach takes into account three types of information ... Keywords: Incremental construction, Information retrieval, Multilingual documents, Thesaurus, Topic Map (TM)

Nebrasse Ellouze; Nadira Lammari; Elisabeth Métais

2012-04-01T23:59:59.000Z

32

An incremental structured part model for image classification  

Science Conference Proceedings (OSTI)

The state-of-the-art image classification methods usually require many training samples to achieve good performance. To tackle this problem, we present a novel incremental method in this paper, which learns a part model to classify objects using only ... Keywords: image classification, incremental learning, semantic parts, structural relationship

Huigang Zhang; Xiao Bai; Jian Cheng; Jun Zhou; Huijie Zhao

2012-11-01T23:59:59.000Z

33

Quantum Dot Fluorescence Lifetime Engineering with DNA ...  

Science Conference Proceedings (OSTI)

Quantum Dot Fluorescence Lifetime Engineering with DNA Origami ... such as metal nanoparticles and semiconductor quantum dots – is challenging ...

34

Tax Increment Financing (TIF) Guarantee Program (Pennsylvania) | Department  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

TIF) Guarantee Program (Pennsylvania) TIF) Guarantee Program (Pennsylvania) Tax Increment Financing (TIF) Guarantee Program (Pennsylvania) < Back Eligibility Commercial Construction Industrial Installer/Contractor Investor-Owned Utility Local Government Municipal/Public Utility Rural Electric Cooperative Utility Savings Category Alternative Fuel Vehicles Hydrogen & Fuel Cells Buying & Making Electricity Water Home Weatherization Solar Wind Program Info Funding Source Commonwealth Financing Authority (CFA) State Pennsylvania Program Type Loan Program Provider Department of Community and Economic Development The Tax Increment Financing (TIF) Guarantee Program provides credit enhancement to improve market access and lower capital costs through loan guarantees to bond issuers to assist in the development and revitalization

35

Tax Increment Financing (TIF) (Nebraska) | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

TIF) (Nebraska) TIF) (Nebraska) Tax Increment Financing (TIF) (Nebraska) < Back Eligibility Agricultural Commercial Construction Fed. Government Fuel Distributor General Public/Consumer Industrial Installer/Contractor Institutional Investor-Owned Utility Local Government Low-Income Residential Multi-Family Residential Municipal/Public Utility Nonprofit Residential Retail Supplier Rural Electric Cooperative Schools State/Provincial Govt Systems Integrator Transportation Tribal Government Utility Savings Category Alternative Fuel Vehicles Hydrogen & Fuel Cells Buying & Making Electricity Water Home Weatherization Solar Wind Program Info State Nebraska Program Type PACE Financing Provider Economic Development Tax Increment Financing (TIF) Nebraska is primarily designed to finance the public costs associated with a private development project. Essentially,

36

An Incremental and Nonbinary CSP Solver: The Hyperpolyhedron Search Algorithm  

E-Print Network (OSTI)

An Incremental and Non­binary CSP Solver: The Hyperpolyhedron Search Algorithm Miguel A. Salido and scheduling can be expressed in a natural way as a Constraint Satisfaction Problem (CSP). It is well known that a non­binary CSP can be transformed into an equivalent binary CSP using some of the actual techniques

Rossi, Francesca

37

AgentCubes: Incremental 3D end-user development  

Science Conference Proceedings (OSTI)

3D game development can be an enticing way to attract K-12 students to computer science, but designing and programming 3D games is far from trivial. Students need to achieve a certain level of 3D fluency in modeling, animation, and programming to be ... Keywords: Computational thinking, End-user development, Game design, IT fluency, Incremental 3D, Visual programming

Andri Ioannidou; Alexander Repenning; David C. Webb

2009-08-01T23:59:59.000Z

38

Raging incrementalism: harnessing change with open-source software  

Science Conference Proceedings (OSTI)

Change is a bitter fact of life for system developers and, to a large extent, conventional practices are aimed at arresting change and minimizing its effects. We take the opposite view and are exploring system engineering practices that harness the forces ... Keywords: open source, raging incrementalism, representational state transfer

John C. Georgas; Michael M. Gorlick; Richard N. Taylor

2005-07-01T23:59:59.000Z

39

PEVELOPMENT OF FLUORESCENCE LIFETIME DIAGNOSTIC  

Office of Scientific and Technical Information (OSTI)

4 4 PEVELOPMENT OF FLUORESCENCE LIFETIME DIAGNOSTIC w I Project Accomplishments Summary (Attachment I) CRADA NO. TSB-1449-97 Date: U 1 8 1 9 8 Revision: 1 A . Parties The project is a relationship between the Lawrence Livennore National Laboratoq (LLNL) and Optiphase, Inc. University of California Lawrence Livermore National Laboratory 7000 East Avenue, L-399 Livermore, CA 94550 Optiphase, h c 7652 Haskell Ave. Van Nuys, CA 91406 Technical Contact - D r . Pepe Davis (8 18)782-0997ext 1 12 B . Background Fiber-optic-based sensors are excellent candidates for detecting the presence and monitoring the levels of degradation products in stockpiled weapons. Specifically, fl uorescence-based sensors are extremely sensitive, can have high specificity for compounds of interest, and are "e~ectrically

40

Measurement of the $?$-lepton lifetime at Belle  

E-Print Network (OSTI)

The lifetime of the $\\tau$-lepton is measured using the process $e^+e^-\\rightarrow\\tau^+\\tau^-$, where both $\\tau$-leptons decay to $3\\pi\

Belle Collaboration; K. Belous; M. Shapkin; A. Sokolov; I. Adachi; H. Aihara; D. M. Asner; V. Aulchenko; A. M. Bakich; A. Bala; B. Bhuyan; A. Bobrov; A. Bondar; G. Bonvicini; A. Bozek; M. Bra?ko; T. E. Browder; D. ?ervenkov; V. Chekelian; A. Chen; B. G. Cheon; K. Chilikin; R. Chistov; K. Cho; V. Chobanova; Y. Choi; D. Cinabro; J. Dalseno; Z. Doležal; D. Dutta; S. Eidelman; D. Epifanov; H. Farhat; J. E. Fast; T. Ferber; V. Gaur; S. Ganguly; A. Garmash; R. Gillard; Y. M. Goh; B. Golob; J. Haba; T. Hara; K. Hayasaka; H. Hayashii; Y. Hoshi; W. -S. Hou; T. Iijima; K. Inami; A. Ishikawa; R. Itoh; T. Iwashita; I. Jaegle; T. Julius; E. Kato; H. Kichimi; C. Kiesling; D. Y. Kim; H. J. Kim; J. B. Kim; M. J. Kim; Y. J. Kim; K. Kinoshita; B. R. Ko; P. Kodyš; S. Korpar; P. Križan; P. Krokovny; T. Kuhr; A. Kuzmin; Y. -J. Kwon; J. S. Lange; S. -H. Lee; J. Libby; D. Liventsev; P. Lukin; D. Matvienko; H. Miyata; R. Mizuk; G. B. Mohanty; T. Mori; R. Mussa; Y. Nagasaka; E. Nakano; M. Nakao; M. Nayak; E. Nedelkovska; C. Ng; N. K. Nisar; S. Nishida; O. Nitoh; S. Ogawa; S. Okuno; S. L. Olsen; W. Ostrowicz; G. Pakhlova; C. W. Park; H. Park; H. K. Park; T. K. Pedlar; R. Pestotnik; M. Petri?; L. E. Piilonen; M. Ritter; M. Röhrken; A. Rostomyan; S. Ryu; H. Sahoo; T. Saito; Y. Sakai; S. Sandilya; D. Santel; L. Santelj; T. Sanuki; V. Savinov; O. Schneider; G. Schnell; C. Schwanda; D. Semmler; K. Senyo; O. Seon; V. Shebalin; C. P. Shen; T. -A. Shibata; J. -G. Shiu; B. Shwartz; A. Sibidanov; F. Simon; Y. -S. Sohn; S. Stani?; M. Stari?; M. Steder; T. Sumiyoshi; U. Tamponi; G. Tatishvili; Y. Teramoto; K. Trabelsi; T. Tsuboyama; M. Uchida; S. Uehara; T. Uglov; Y. Unno; S. Uno; Y. Usov; S. E. Vahsen; C. Van Hulse; P. Vanhoefer; G. Varner; K. E. Varvell; A. Vinokurova; V. Vorobyev; M. N. Wagner; C. H. Wang; P. Wang; M. Watanabe; Y. Watanabe; K. M. Williams; E. Won; J. Yamaoka; Y. Yamashita; S. Yashchenko; Y. Yook; C. Z. Yuan; Z. P. Zhang; V. Zhilich; A. Zupanc

2013-10-31T23:59:59.000Z

Note: This page contains sample records for the topic "incremental lifetime cancer" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


41

Remote plunger removal device for small-scale incremental pressing  

SciTech Connect

Small-scale pressing of high explosives (HE) at Los Alamos National Laboratory (LANL) and elsewhere is routinely performed using pneumatic presses. Blast shields provide protection to the operator during the pressing procedure, but safety of the operator is a concern during removal of the plunger, which is currently performed manually. To minimize this risk, very high tolerances between the plunger and the die are required. These tolerances are often very costly, especially in the case of long, relatively narrow dies. The safety issue is an even greater concern with incremental pressing in which cleaning the die between increments is difficult or impossible. To better protect press operators, a device has been designed and constructed to allow remote plunger removal in a standard HE press. In this report the authors describe this modified press that allows remote removal of the plunger.

Burnside, N.J.; Son, S.F.; Asay, B.W.

1997-09-01T23:59:59.000Z

42

Evaluation of an Incremental Ventilation Energy Model for Estimating  

NLE Websites -- All DOE Office Websites (Extended Search)

Evaluation of an Incremental Ventilation Energy Model for Estimating Evaluation of an Incremental Ventilation Energy Model for Estimating Impacts of Air Sealing and Mechanical Ventilation Title Evaluation of an Incremental Ventilation Energy Model for Estimating Impacts of Air Sealing and Mechanical Ventilation Publication Type Report LBNL Report Number LBNL-5796E Year of Publication 2012 Authors Logue, Jennifer M., William J. N. Turner, Iain S. Walker, and Brett C. Singer Date Published 06/2012 Abstract Changing the rate of airflow through a home affects the annual thermal conditioning energy.Large-scale changes to airflow rates of the housing stock can significantly alter the energy consumption of the residential energy sector. However, the complexity of existing residential energy models hampers the ability to estimate the impact of policy changes on a state or nationwide level. The Incremental Ventilation Energy (IVE) model developed in this study was designed to combine the output of simple airflow models and a limited set of home characteristics to estimate the associated change in energy demand of homes. The IVE model was designed specifically to enable modelers to use existing databases of home characteristics to determine the impact of policy on ventilation at a population scale. In this report, we describe the IVE model and demonstrate that its estimates of energy change are comparable to the estimates of a well-validated, complex residential energy model when applied to homes with limited parameterization. Homes with extensive parameterization would be more accurately characterized by complex residential energy models. The demonstration included a range of home types, climates, and ventilation systems that cover a large fraction of the residential housing sector.

43

Dynamic Rotor Deformation and Vibration Monitoring Using a Non-Incremental Laser Doppler Distance Sensor  

Science Conference Proceedings (OSTI)

Monitoring rotor deformations and vibrations dynamically is an important task for improving the safety and the lifetime as well as the energy efficiency of motors and turbo machines. However, due to the high rotor speed encountered in particular at turbo machines, this requires concurrently a high measurement rate and high accuracy, which can not be fulfilled by most commercially available sensors. To solve this problem, we developed a non-incremental laser Doppler distance sensor (LDDS), which is able to measure simultaneously the in-plane velocity and the out-of-plane position of moving rough solid objects with micrometer precision. In addition, this sensor concurrently offers a high temporal resolution in the microsecond range, because its position uncertainty is in principle independent of the object velocity in contrast to conventional distance sensors, which is a unique feature of the LDDS. Consequently, this novel sensor enables precise and dynamic in-process deformation and vibration measurements on rotating objects, such as turbo machine rotors, even at very high speed. In order to evidence the capability of the LDDS, measurements of rotor deformations (radial expansion), vibrations and wobbling motions are presented at up to 50,000 rpm rotor speed.

Pfister, Thorsten; Guenther, Philipp; Dreier, Florian; Czarske, Juergen [Technische Universitaet Dresden, Faculty of Electrical Engineering and Information Technology, Laboratory for Measurement and Testing Techniques, Helmholtzstrasse 18, D-01062 Dresden (Germany)

2010-05-28T23:59:59.000Z

44

Generation of pornographic blacklist and its incremental update using an inverse chi-square based method  

Science Conference Proceedings (OSTI)

This study presented an inverse chi-square based web content classification system that works along with an incremental update mechanism for incremental generation of pornographic blacklist. The proposed system, as indicated from the experimental results, ... Keywords: Incremental update, Inverse chi-square function, Pornographic blacklist, Web content classification

Lung-Hao Lee; Cheng-Jye Luh

2008-09-01T23:59:59.000Z

45

Using National Survey Data to Estimate Lifetimes of Residential...  

NLE Websites -- All DOE Office Websites (Extended Search)

National Survey Data to Estimate Lifetimes of Residential Appliances Title Using National Survey Data to Estimate Lifetimes of Residential Appliances Publication Type Journal...

46

Reduction of Statistical Power Per Event Due to Upper Lifetime Cuts in Lifetime Measurements  

E-Print Network (OSTI)

A cut on the maximum lifetime in a lifetime fit not only reduces the number of events, but also, in some circumstances dramatically, decreases the statistical significance of each event. The upper impact parameter cut in the hadronic B trigger at CDF, which is due to technical limitations, has the same effect. In this note we describe and quantify the consequences of such a cut on lifetime measurements. We find that even moderate upper lifetime cuts, leaving event numbers nearly unchanged, can dramatically increase the statistical uncertainty of the fit result.

Jonas Rademacker

2005-02-25T23:59:59.000Z

47

Martzloff Cited for Lifetime Achievement by IEEE Standards ...  

Science Conference Proceedings (OSTI)

Martzloff Cited for Lifetime Achievement by IEEE Standards Association. From NIST Tech Beat: December 12, 2012. ...

2013-05-21T23:59:59.000Z

48

Mixing and Lifetimes of b-hadrons  

Science Conference Proceedings (OSTI)

We review the status of mixing and lifetimes of b-hadrons. We will show that {delta}{gamma}/{delta}M, a{sub sl} and {phi} are better suited to search for new physics effects than {delta}M alone, because of our poor knowledge of the decay constants. The theoretical precision in the determination of {gamma}{sub 12}/M{sub 12}--which contains all information on {delta}{gamma}/{delta}M, a{sub sl} and {phi}--can be tested directly by investigating the lifetimes of b-hadrons, because both quantities rely on the same theoretical footing. In particular we will also present a numerical estimate for the lifetime of the {xi}{sub b}-baryon.

Lenz, Alexander J. [Fakultaet fuer Physik, Universitaet Regensburg, 93040 Regensburg (Germany)

2008-07-02T23:59:59.000Z

49

Prompt Neutron Lifetime for the NBSR Reactor  

SciTech Connect

In preparation for the proposed conversion of the National Institute of Standards and Technology (NIST) research reactor (NBSR) from high-enriched uranium (HEU) to low-enriched uranium (LEU) fuel, certain point kinetics parameters must be calculated. We report here values of the prompt neutron lifetime that have been calculated using three independent methods. All three sets of calculations demonstrate that the prompt neutron lifetime is shorter for the LEU fuel when compared to the HEU fuel and longer for the equilibrium end-of-cycle (EOC) condition when compared to the equilibrium startup (SU) condition for both the HEU and LEU fuels.

Hanson, A.L.; Diamond, D.

2012-06-24T23:59:59.000Z

50

Evaluation of Methodologies for Real-Time Incremental Heat Rate Determination  

Science Conference Proceedings (OSTI)

Reduced staffing, tighter budgets, ISOs, and increased competition have created the need for maintaining up-to-date incremental heat rate information. Combining recent advances in analytics with modern performance monitoring packages and data historians may provide the capability for closer-to-real-time incremental heat rate determination. Many power generating companies either rely on historic data or slow and labor intensive testing to establish incremental heat rate curves. Those curves are ...

2013-11-26T23:59:59.000Z

51

Materials Education: Opportunities over a Lifetime  

SciTech Connect

A report, in the form of abbreviated notes, of the 17th Biennial Conference on National Materials Policy ''Materials Education: Opportunities over a Lifetime'' held May 20-21, 2002 in College Park, MD, sponsored by the Federation of Materials Societies and the University Materials Council.

Anderson, Iver E.; Schwartz, Lyle H.; Faber, Katherine T.; Cargill III, G. Slade; Houston, Betsy

2003-10-28T23:59:59.000Z

52

Incremental Impacts of Energy Efficiency Policy Initiatives Relative to the 2009  

E-Print Network (OSTI)

Incremental Impacts of Energy Efficiency Policy Initiatives Relative to the 2009 Integrated Energy Policy Report Adopted Demand Forecast ATTACHMENT A: TECHNICAL REPORT Prepared For: California Energy;Incremental Impacts of Energy Efficiency Policy Initiatives Relative to the 2009 Integrated Energy Policy

53

An improved incremental training algorithm for support vector machines using active query  

Science Conference Proceedings (OSTI)

In this paper, we present an improved incremental training algorithm for support vector machines (SVMs). Instead of selecting training samples randomly, we divide them into groups and apply the k-means clustering algorithm to collect the initial set ... Keywords: Active learning, Clustering algorithm, Incremental training, Pattern classification, Support vector machine

Shouxian Cheng; Frank Y. Shih

2007-03-01T23:59:59.000Z

54

Bi-parameter incremental unknowns ADI iterative methods for elliptic problems  

Science Conference Proceedings (OSTI)

Bi-parameter incremental unknowns (IU) alternating directional implicit (ADI) iterative methods are proposed for solving elliptic problems. Condition numbers of the coefficient matrices for these iterative schemes are carefully estimated. Theoretical ... Keywords: Bi-parameter ADI iterative method, Condition number, Convergence analysis, Incremental unknowns

Aili Yang; Yujiang Wu; Yongqing Wu; Dawei Ren

2012-07-01T23:59:59.000Z

55

Fuzzy incremental control algorithm of loop heat pipe cooling system for spacecraft applications  

Science Conference Proceedings (OSTI)

Reliable and high precision thermal control technologies are essential for the safe flight of advanced spacecraft. A fuzzy incremental control strategy is proposed for control of an LHP space cooling system comprising a loop heat pipe and a variable ... Keywords: Fuzzy incremental control, Loop heat pipe, Modeling and simulation, Space cooling system

Su-Jun Dong; Yun-Ze Li; Jin Wang; Jun Wang

2012-09-01T23:59:59.000Z

56

Incorporating site-level knowledge for incremental crawling of web forums: a list-wise strategy  

Science Conference Proceedings (OSTI)

We study in this paper the problem of incremental crawling of web forums, which is a very fundamental yet challenging step in many web applications. Traditional approaches mainly focus on scheduling the revisiting strategy of each individual page. However, ... Keywords: incremental crawling, sitemap, web forum

Jiang-Ming Yang; Rui Cai; Chunsong Wang; Hua Huang; Lei Zhang; Wei-Ying Ma

2009-06-01T23:59:59.000Z

57

An incremental deployment algorithm for wireless sensor networks using one or multiple autonomous agents  

Science Conference Proceedings (OSTI)

The paper studies the deployment problem of wireless sensor networks using one or multiple autonomous agents. An online incremental algorithm based on Voronoi partition is proposed to solve the problem, for which each agent deploys sensors one-at-a-time ... Keywords: Autonomous agent, Incremental deployment, Sensor network

Zhiyun Lin; Sijian Zhang; Gangfeng Yan

2013-01-01T23:59:59.000Z

58

Mass and Lifetime Measurements in Storage Rings  

Science Conference Proceedings (OSTI)

Masses of nuclides covering a large area of the chart of nuclides can be measured in storage rings where many ions circulate at the same time. In this paper the recent progress in the analysis of Schottky mass spectrometry data is presented as well as the technical improvements leading to higher accuracy for isochronous mass measurements with a time-of-flight detector. The high sensitivity of the Schottky method down to single ions allows to measure lifetimes of nuclides by observing mother and daughter nucleus simultaneously. In this way we investigated the decay of bare and H-like 140Pr. As we could show the lifetime can be even shortened compared to those of atomic nuclei despite of a lower number of electrons available for internal conversion or electron capture.All these techniques will be implemented with further improvements at the storage rings of the new FAIR facility at GSI in the future.

Weick, H.; Beckert, K.; Beller, P.; Bosch, F.; Dimopoulou, C.; Kozhuharov, C.; Kurcewicz, J.; Mazzocco, M.; Nociforo, C.; Nolden, F.; Steck, M.; Sun, B.; Winkler, M. [Gesellschaft fuer Schwerionenforschung mbH, 64291 Darmstadt (Germany); Brandau, C.; Chen, L.; Geissel, H.; Knoebel, R.; Litvinov, S. A.; Litvinov, Yu. A.; Scheidenberger, C. [Gesellschaft fuer Schwerionenforschung mbH, 64291 Darmstadt (Germany); II. Phys. Institut, Justus-Liebig-Universitaet Giessen, 35392 Giessen (Germany)] (and others)

2007-05-22T23:59:59.000Z

59

ICALEPCS Lifetime Achievement Award to Martin Kraimer  

NLE Websites -- All DOE Office Websites (Extended Search)

Cockroaches Advance Student's Study of Ancient Life Cockroaches Advance Student's Study of Ancient Life Bringing Fruit Flies in from the Cold DOE Environmental Sustainability Award to Three from APS 2009 Chemistry Nobel to APS Users The First Experiment at the LCLS APS News Archives: 2012 | 2011 | 2010 | 2009 2008 | 2007 | 2006 | 2005 2004 | 2003 | 2002 | 2001 2000 Subscribe to APS News rss feed ICALEPCS Lifetime Achievement Award to Martin Kraimer OCTOBER 28, 2009 Bookmark and Share Left to right: Ryotaro Tanaka (ICALEPCS2009 Chair), Jeffrey O. Hill, Martin R. Kraimer, Bob Daleisio, and In Soo Ko (ICALEPCS ISAC Chair), October 15, 2009, Kobe Japan. Martin R. Kraimer, formerly of the Controls Group in the Argonne APS Engineering Support Division, is one of three recipients of the first Lifetime Achievement Award presented by the ICALEPCS International

60

B mixing and lifetimes at the Tevatron  

SciTech Connect

The Tevatron collider at Fermilab provides a very rich environment for the study of b-hadrons. Both the D0 and CDF experiments have collected a sample of about 1 fb{sup -1}. they report results on three topics: b-hadron lifetimes, polarization amplitudes and the decay width difference in B{sub s}{sup 0} {yields} J/{psi}{phi}, and B{sub s}{sup 0} mixing.

Gomez-Ceballos, G.; /Cantabria Inst. of Phys.; Piedra, J.; /Paris U., VI-VII

2006-04-01T23:59:59.000Z

Note: This page contains sample records for the topic "incremental lifetime cancer" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


61

Measurement of Beam Lifetime and Applications for SPEAR3  

SciTech Connect

Beam lifetime studies for the SPEAR3 storage ring are presented. The three lifetime components are separated with lifetime measurements under various combinations of beam currents and fill patterns and vertical scraper scans. Touschek lifetime is studied with rf voltage scans and with the horizontal or vertical scrapers inserted. The measurements are explained with calculations based on the calibrated lattice model. Quantum lifetime measurements are performed with reduced longitudinal and horizontal apertures, respectively, from which we deduce the radiation energy loss down to a few keV per revolution and the horizontal beam size.

Huang, Xiaobiao; Corbett, Jeff; /SLAC

2011-04-05T23:59:59.000Z

62

Final report on reliability and lifetime prediction.  

Science Conference Proceedings (OSTI)

This document highlights the important results obtained from the subtask of the Goodyear CRADA devoted to better understanding reliability of tires and to developing better lifetime prediction methods. The overall objective was to establish the chemical and physical basis for the degradation of tires using standard as well as unique models and experimental techniques. Of particular interest was the potential application of our unique modulus profiling apparatus for assessing tire properties and for following tire degradation. During the course of this complex investigation, extensive relevant information was generated, including experimental results, data analyses and development of models and instruments. Detailed descriptions of the findings are included in this report.

Gillen, Kenneth Todd; Wise, Jonathan; Jones, Gary D.; Causa, Al G. [Goodyear Tire and Rubber Co., Akron, OH; Terrill, Edward R. [Goodyear Tire and Rubber Co., Akron, OH; Borowczak, Marc [Goodyear Tire and Rubber Co., Akron, OH

2012-12-01T23:59:59.000Z

63

Street as structure : an approach to the incremental development of Fort Point Channel  

E-Print Network (OSTI)

This work seeks to create an approach to the incremental development of a warehouse district in the City of Boston. The focus of the thesis is on the generation of rules and an implementation process that will organize the ...

Powers, Darleen D

1980-01-01T23:59:59.000Z

64

On maximizing lifetime of a sensor cluster  

E-Print Network (OSTI)

We consider the energy consumed in radio transmission of a set of sensors forming a data gathering wireless network. Our objective is to enhance the lifetime of such networks by exploiting three system-level opportunities. Firstly, the number of bits to be transmitted can be reduced by taking advantage of the redundancy induced by spatio-temporal correlation in sensor data. Secondly, channel coding allows us to reduce transmission energy at the cost of increased transmission time. Thirdly, sensor nodes can be expected to operate collaboratively, allowing optimal management of distributed energy resources. Our main contribution lies in providing a framework to merge these ideas for energy conscious networking. We pose the problem of maximizing network lifetime as an optimal scheduling problem. We first consider a special case where data rate is linearly proportional to received signal power. In this scenario, we investigate both static and dynamic scheduling strategies. The optimal static schedule turns out to have a very simple form. For the dynamic case, we obtain an integer linear program formulation to find the optimal strategy. We then propose an efficient algorithm that exploits the special nature of the problem setting to quickly find the optimal solution. Finally, we consider the general case where data rates and signal power need not be linearly related and propose an algorithm to find the optimal transmission times subject to the deadline constraint imposed by the system. 1

Samar Agnihotri; Pavan Nuggehalli; H. S. Jamadagni

2005-01-01T23:59:59.000Z

65

Lifetime Evaluation of Elastomeric Polymers for Storage of Nuclear ...  

Science Conference Proceedings (OSTI)

Presentation Title, Lifetime Evaluation of Elastomeric Polymers for Storage of Nuclear Materials. Author(s), Elizabeth Hoffman, Eric Skidmore. On-Site Speaker  ...

66

New Tool Quantitatively Maps Minority-Carrier Lifetime of Multicrystal...  

NLE Websites -- All DOE Office Websites (Extended Search)

and Integration Laboratory (PDIL) to generate quantitative minority-carrier lifetime maps of multicrystalline silicon (mc-Si) bricks. This feat has been accomplished by using...

67

Using National Survey Data to Estimate Lifetimes of Residential Appliances  

E-Print Network (OSTI)

Life of Residential Appliances,” in ACEEE Summer Study onWhen do energy-efficient appliances generate energy savings?points. Assuming unchanging appliance lifetimes expands and

Lutz, James D.

2013-01-01T23:59:59.000Z

68

Stream data gathering in wireless sensor networks within expected lifetime  

Science Conference Proceedings (OSTI)

Sensor networks aim at collecting important sensor data for environment monitoring, e-health or hazardous conditions. Some applications do not need sensor networks with a long lifetime, such as monitoring an erupting volcano or monitoring hazardous conditions. ... Keywords: expected lifetime, sensor network, stream data gathering

Lei Shu; Zhangbing zhou; Antonio Aguilar; Manfred Hauswirth

2007-08-01T23:59:59.000Z

69

Lifetime embrittlement of reactor core materials  

DOE Green Energy (OSTI)

Over a core lifetime, the reactor materials Zircaloy-2, Zircaloy-4, and hafnium may become embrittled due to the absorption of corrosion- generated hydrogen and to neutron irradiation damage. Results are presented on the effects of fast fluence on the fracture toughness of wrought Zircaloy-2, Zircaloy-4, and hafnium; Zircaloy-4 to hafnium butt welds; and hydrogen precharged beta treated and weld metal Zircaloy-4 for fluences up to a maximum of approximately 150 x 10{sup 24} n/M{sup 2} (> 1 Mev). While Zircaloy-4 did not exhibit a decrement in K{sub IC} due to irradiation, hafnium and butt welds between hafnium and Zircaloy-4 are susceptible to embrittlement with irradiation. The embrittlement can be attributed to irradiation strengthening, which promotes cleavage fracture in hafnium and hafnium-Zircaloy welds, and, in part, to the lower chemical potential of hydrogen in Zircaloy-4 compared to hafnium, which causes hydrogen, over time, to drift from the hafnium end toward the Zircaloy-4 end and to precipitate at the interface between the weld and base-metal interface. Neutron radiation apparently affects the fracture toughness of Zircaloy-2, Zircaloy-4, and hafnium in different ways. Possible explanations for these differences are suggested. It was found that Zircaloy-4 is preferred over Zircaloy-2 in hafnium-to- Zircaloy butt-weld applications due to its absence of a radiation- induced reduction in K{sub IC} plus its lower hydrogen absorption characteristics compared with Zircaloy-2.

Kreyns, P.H..; Bourgeois, W.F.; Charpentier, P.L.; Kammenzind, B.F.; Franklin, D.G. [Bettis Atomic Power Lab., West Mifflin, PA (United States); White, C.J. [Knolls Atomic Power Lab., Schenectady, NY (United States)

1994-08-01T23:59:59.000Z

70

Neutron lifetime measurements using gravitationally trapped ultracold neutrons  

E-Print Network (OSTI)

Our experiment using gravitationally trapped ultracold neutrons (UCN) to measure the neutron lifetime is reviewed. Ultracold neutrons were trapped in a material bottle covered with perfluoropolyether. The neutron lifetime was deduced from comparison of UCN losses in the traps with different surface-to-volume ratios. The precise value of the neutron lifetime is of fundamental importance to particle physics and cosmology. In this experiment, the UCN storage time is brought closer to the neutron lifetime than in any experiments before:the probability of UCN losses from the trap was only 1% of that for neutron beta decay. The neutron lifetime obtained,878.5+/-0.7stat+/-0.3sys s, is the most accurate experimental measurement to date.

A. P. Serebrov; V. E. Varlamov; A. G. Kharitonov; A. K. Fomin; Yu. N. Pokotilovski; P. Geltenbort; I. A. Krasnoschekova; M. S. Lasakov; R. R. Taldaev; A. V. Vassiljev; O. M. Zherebtsov

2007-02-06T23:59:59.000Z

71

Lifetime Extension of the Phenix Plant  

SciTech Connect

The French fast reactor prototype Phenix was put into commercial operation in 1974. The total time of power operation of the plant is [approximately]100000 h representing 3860 equivalent fuel power days (EFPD). With the initial objective of the demonstration of fast breeder reactors achieved, since the early 1990s, the role of the reactor as an irradiation facility has been emphasized, particularly in support of the Commissariat a l'Energie Atomique research and development program on long-lived radioactive waste transmutation. This new objective required an extension of the planned reactor lifetime. A major renovation program was carried out in the plant from 1994 to 2003, involving safety upgrading, component inspections and repairs, and the 10-yr statutory maintenance. The main work consisted of the addition of a backup control rod to the reactor; improvement of earthquake protection by reinforcement of buildings and components and replacement of the emergency water cooling circuit; improvement of protection against sodium fire by partitioning the secondary sodium circuit in the steam generator building, reinforcement of steam generator casing, and installation of an antiwhip system on the high-pressure steam pipes; replacement of hot parts of the 321 stainless steel secondary loops and steam generator modules, affected by delayed reheat cracking; special inspections of the reactor internal structures to demonstrate their good condition. An extensive plant requalification program was carried out following the renovation work, and the plant resumed power operation in June 2003. Six operating cycles are planned, representing a total irradiation time of 720 EFPD equivalent to [approximately]5.5 yr of operation.

Guidez, J. [Commissariat a l'Energie Atomique (France); Le Coz, P. [Commissariat a l'Energie Atomique (France); Martin, L. [Commissariat a l'Energie Atomique (France); Mariteau, P. [Electricite de France (France); Dupraz, R. [Framatome-ANP (France)

2005-04-15T23:59:59.000Z

72

E cient Incremental Algorithms for the Sparse Resultant and the Mixed Volume  

E-Print Network (OSTI)

of the algorithm is presented and empirical results are reported which suggest that it is the fastest mixed volumeE cient Incremental Algorithms for the Sparse Resultant and the Mixed Volume IOANNIS Z. EMIRISzAND JOHN F. CANNYx zProjet SAFIR, I.N.R.I.A., B.P. 93, 06902 Sophia-Antipolis, France. emiris

O'Brien, James F.

73

Deferred incremental refresh of XML materialized views: algorithms and performance evaluation  

Science Conference Proceedings (OSTI)

The view mechanism can provide the user with an appropriate portion of database through data filtering and integration. Views are often materialized for query performance improvement, and in that case, their consistency needs to be maintained against ... Keywords: XML, deferred incremental view refresh, materialized view, semistructured data

Hyunchul Kang; Hosang Sung; ChanHo Moon

2003-01-01T23:59:59.000Z

74

Simplified and Regular Physical Parameterizations for Incremental Four-Dimensional Variational Assimilation  

Science Conference Proceedings (OSTI)

A set of physical parameterizations has been developed for inclusion in incremental four-dimensional variational assimilation (4D-Var). The goal for this physical package is that it be simple, regular (for the efficiency of the minimization in 4D-...

Marta Janisková; Jean-Noël Thépaut; Jean-François Geleyn

1999-01-01T23:59:59.000Z

75

Literature Review of Data on the Incremental Costs to Design and Build Low-Energy Buildings  

Science Conference Proceedings (OSTI)

This document summarizes findings from a literature review into the incremental costs associated with low-energy buildings. The goal of this work is to help establish as firm an analytical foundation as possible for the Building Technology Program's cost-effective net-zero energy goal in the year 2025.

Hunt, W. D.

2008-05-14T23:59:59.000Z

76

Variance Optimal Hedging for continuous time processes with independent increments and applications  

E-Print Network (OSTI)

For a large class of vanilla contingent claims, we establish an explicit F\\"ollmer-Schweizer decomposition when the underlying is a process with independent increments (PII) and an exponential of a PII process. This allows to provide an efficient algorithm for solving the mean variance hedging problem. Applications to models derived from the electricity market are performed.

Goutte, Stéphane; Russo, Francesco

2009-01-01T23:59:59.000Z

77

Learning generative visual models from few training examples: An incremental Bayesian approach tested on 101 object categories  

Science Conference Proceedings (OSTI)

Current computational approaches to learning visual object categories require thousands of training images, are slow, cannot learn in an incremental manner and cannot incorporate prior information into the learning process. In addition, no algorithm ... Keywords: Bayesian model, Categorization, Generative model, Incremental learning, Object recognition

Li Fei-Fei; Rob Fergus; Pietro Perona

2007-04-01T23:59:59.000Z

78

The effect of moving from a plan-driven to an incremental software development approach with agile practices  

Science Conference Proceedings (OSTI)

So far, only few in-depth studies focused on the direct comparison of process models in general, and between plan-driven and incremental/agile approaches in particular. That is, it is not made explicit what the effect is of moving from one model to another ... Keywords: Agile, Case study, Incremental, Migration, Plan-driven

Kai Petersen; Claes Wohlin

2010-12-01T23:59:59.000Z

79

Lifetime of the Highly Efficient H- Ion Sources  

Science Conference Proceedings (OSTI)

Factors limiting the operating lifetime of Compact Surface Plasma Sources (CSPS) are analyzed and possible treatments for lifetime enhancement are considered. Noiseless discharges with lower gas and cesium densities are produced in experiments with modified discharge cells. With these discharge cells it is possible to increase the emission aperture and extract the same beam with a lower discharge current and with correspondingly increased source lifetime. A design of an advanced CSPS is presented. Optimization of the discharge cells in a Penning H{sup -} ion source is a viable method for increasing the phase space of the stable region for noiseless discharge production. With this method, cesium usage would be decreased, potentially resulting in longer source lifetimes.

Bollinger, D.S.; /Fermilab; Dudnikov, V.G.; /MUONS Inc., Batavia; Faircloth, D.C.; Lawrie, S.R.; /Rutherford

2012-05-01T23:59:59.000Z

80

Long lifetime operation of an ArF-excimer laser  

Science Conference Proceedings (OSTI)

lifetime of a discharge-excited ArF-excimer laser is pre- sented. The three ... are CF4 generation in the laser gas, color-center forma- tion in the optics and input ...

Note: This page contains sample records for the topic "incremental lifetime cancer" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


81

Lifetime of solar flare particles in coronal storage regions  

Science Conference Proceedings (OSTI)

Most discussions of lifetime of flare particles in the solar corona have ... However, it is quite possible that the solar cosmic rays are not imbedded in I0 a K coronal.

82

Orientation-Dependent Entanglement Lifetime in a Squeezed Atomic Clock  

E-Print Network (OSTI)

We study experimentally the application of a class of entangled states, squeezed spin states, to the improvement of atomic-clock precision. In the presence of anisotropic noise, the entanglement lifetime is strongly dependent ...

Leroux, Ian Daniel

83

Measurement of the lifetimes of B meson mass eigenstates  

E-Print Network (OSTI)

In this dissertation, we present the results of the average lifetime measurements in ..., ..., and ... decays, as well as the results of a time-dependent angular analysis of ... and ... decays. The time-dependent angular ...

Anikeev, Konstantin

2004-01-01T23:59:59.000Z

84

Orientation-Dependent Entanglement Lifetime in a Squeezed Atomic Clock  

E-Print Network (OSTI)

We study experimentally the lifetime of a special class of entangled states in an atomic clock, squeezed spin states. In the presence of anisotropic noise, their lifetime is strongly dependent on squeezing orientation. We measure the Allan deviation spectrum of a clock operated with a phase-squeezed input state. For integration times up to 50 s the squeezed clock achieves a given precision 2.8(3) times faster than a clock operating at the standard quantum limit.

Ian D. Leroux; Monika H. Schleier-Smith; Vladan Vuleti?

2010-04-10T23:59:59.000Z

85

On undrained test using Rowe's relation and Incremental Modelling: Generalisation of the notion of Characteristic State  

E-Print Network (OSTI)

It is recalled that stress-strain incremental modelling is a common feature of most theoretical description of the mechanical behaviour of granular material. An other commonly accepted characteristics of the mechanical behaviour of granular material is the Rowe's relation which links the dilatancy K to the ratio B of vertical-to-lateral stress during a test at constant lateral stress, i.e. B =(1+M)(1+K). Using an incremental modelling, this law shall be interpreted as a pseudo-Poisson coefficient. We combine these two features to solve the problem of an axial compression under undrained condition. We demonstrate that the sample is submitted to a bifurcation of the transcritical type when it reaches the q=Mp line. This allows extending the notion of the characteristic state introduced by Luong to other situations and to anisotropic systems. We show also that these undrained tests are quite appropriate to study the characteristic-state behaviour.

P. Evesque

2005-06-14T23:59:59.000Z

86

Understanding the Impacts of Incremental Gas Supply on the Flow Dynamics Across the North American Grid  

Reports and Publications (EIA)

The presentation "Understanding the Impacts of Incremental Gas Supply on the Flow Dynamics Across the North American Grid" was given at the Canadian Institute's BC LNG Forum on November 20, 2006. The presentation provides an overview of EIA's long-term natural gas projections under reference case and sensitivity cases from the Annual Energy Outlook 2006, with special emphasis on natural gas flows in the West Coast.

Information Center

2006-12-14T23:59:59.000Z

87

Incremental cost of electricity used as backup for passive heated homes  

DOE Green Energy (OSTI)

The impact of passive technologies on a north-central US utility has been studied. A method of utility cost and fuel use analysis, developed at Brookhaven National Laboratory, was used to compute the long run incremental costs and incremental fuel use required for supplementary electricity to houses with Trombe walls or with direct gain features. For comparison, a reference house with no passive features and a house with an energy conservation design were also analyzed. The results show that the total long run incremental cost to the utility of providing supplementary power to the passive houses costs no more than the cost to supply electricity to heat the reference house or the conservation house. An analysis of the annual homeowner costs for the various types of heating systems suggests that the Trombe wall technology is not promising for use in this climate. The passive technologies, as modelled in this study reduced the requirements for conventional energy by about 10% (7 to 10 kilojoules/year). For all of the house types studied, the use of electricity for heating, instead of oil or gas, reduced the overall (utility plus residential) use of oil or gas by only about 30 to 40% even out through the 1990's.

Martorella, J; Bright, R; Davitian, H

1980-08-01T23:59:59.000Z

88

Models for Battery Reliability and Lifetime: Applications in Design and Health Management (Presentation)  

DOE Green Energy (OSTI)

This presentation discusses models for battery reliability and lifetime and the Battery Ownership Model.

Smith, K.; Neubauer, J.; Wood, E.; Jun, M.; Pesaran, A.

2013-06-01T23:59:59.000Z

89

Beam lifetime and limitations during low-energy RHIC operation  

SciTech Connect

The low-energy physics program at the Relativistic Heavy Ion Collider (RHIC), motivated by a search for the QCD phase transition critical point, requires operation at low energies. At these energies, large nonlinear magnetic field errors and large beam sizes produce low beam lifetimes. A variety of beam dynamics effects such as Intrabeam Scattering (IBS), space charge and beam-beam forces also contribute. All these effects are important to understand beam lifetime limitations in RHIC at low energies. During the low-energy RHIC physics run in May-June 2010 at beam {gamma} = 6.1 and {gamma} = 4.1, gold beam lifetimes were measured for various values of space-charge tune shifts, transverse acceptance limitation by collimators, synchrotron tunes and RF voltage. This paper summarizes our observations and initial findings.

Fedotov, A.V.; Bai, M.; Blaskiewicz, M.; Fischer, W.; Kayran, D.; Montag, C.; Satogata, T.; Tepikian, S.; Wang, G.

2011-03-28T23:59:59.000Z

90

Better Methods for Predicting Lifetimes of Seal Materials  

Science Conference Proceedings (OSTI)

We have been working for many years to develop better methods for predicting the lifetimes of polymer materials. Because of the recent interest in extending the lifetimes of nuclear weapons and the importance of environmental seals (o-rings, gaskets) for protecting weapon interiors against oxygen and water vapor, we have recently turned our attention to seal materials. Perhaps the most important environmental o-ring material is butyl rubber, used in various military applications. Although it is the optimum choice from a water permeability perspective, butyl can be marginal from an aging point-of-view. The purpose of the present work was to derive better methods for predicting seal lifetimes and applying these methods to an important butyl material, Parker compound B6 12-70.

Celina, M.; Gillen, K.T.; Keenan, M.R.

1999-03-16T23:59:59.000Z

91

Spectrum Fatigue Lifetime and Residual Strength for Fiberglass Laminates  

SciTech Connect

This report addresses the effects of spectrum loading on lifetime and residual strength of a typical fiberglass laminate configuration used in wind turbine blade construction. Over 1100 tests have been run on laboratory specimens under a variety of load sequences. Repeated block loading at two or more load levels, either tensile-tensile, compressive-compressive, or reversing, as well as more random standard spectra have been studied. Data have been obtained for residual strength at various stages of the lifetime. Several lifetime prediction theories have been applied to the results. The repeated block loading data show lifetimes that are usually shorter than predicted by the most widely used linear damage accumulation theory, Miner's sum. Actual lifetimes are in the range of 10 to 20 percent of predicted lifetime in many cases. Linear and nonlinear residual strength models tend to fit the data better than Miner's sum, with the nonlinear providing a better fit of the two. Direct tests of residual strength at various fractions of the lifetime are consistent with the residual strength models. Load sequencing effects are found to be insignificant. The more a spectrum deviates from constant amplitude, the more sensitive predictions are to the damage law used. The nonlinear model provided improved correlation with test data for a modified standard wind turbine spectrum. When a single, relatively high load cycle was removed, all models provided similar, though somewhat non-conservative correlation with the experimental results. Predictions for the full spectrum, including tensile and compressive loads were slightly non-conservative relative to the experimental data, and accurately captured the trend with varying maximum load. The nonlinear residual strength based prediction with a power law S-N curve extrapolation provided the best fit to the data in most cases. The selection of the constant amplitude fatigue regression model becomes important at the lower stress, higher cycle loading cases. The residual strength models may provide a more accurate estimate of blade lifetime than Miner's rule for some loads spectra. They have the added advantage of providing an estimate of current blade strength throughout the service life.

WAHL, NEIL K.; MANDELL, JOHN F.; SAMBORSKY, DANIEL D.

2002-03-01T23:59:59.000Z

92

An Examination of the Incremental Balance in a Global Ensemble-Based 3D-Var Data Assimilation System  

Science Conference Proceedings (OSTI)

This study examines the modification to the balance properties of the analysis increments in a global three-dimensional variational data assimilation scheme when using flow-dependent background-error covariances derived from an operational ...

Jean-François Caron; Luc Fillion

2010-10-01T23:59:59.000Z

93

Incremental reference resolution: the task, metrics for evaluation, and a Bayesian filtering model that is sensitive to disfluencies  

Science Conference Proceedings (OSTI)

In this paper we do two things: a) we discuss in general terms the task of incremental reference resolution (IRR), in particular resolution of exophoric reference, and specify metrics for measuring the performance of dialogue system components tackling ...

David Schlangen; Timo Baumann; Michaela Atterer

2009-09-01T23:59:59.000Z

94

Massive sulfide deposits and hydrothermal solutions: incremental reaction modeling of mineral precipitation and sulfur isotopic evolution  

DOE Green Energy (OSTI)

Incremental reaction path modeling of chemical and sulfur isotopic reactions occurring in active hydrothermal vents on the seafloor, in combination with chemical and petrographic data from sulfide samples from the seafloor and massive sulfide ore deposits, allows a detailed examination of the processes involved. This paper presents theoretical models of reactions of two types: (1) adiabatic mixing between hydrothermal solution and seawater, and (2) reaction of hydrothermal solution with sulfide deposit materials. In addition, reaction of hydrothermal solution with sulfide deposit minerals and basalt in feeder zones is discussed.

Janecky, D.R.

1986-01-01T23:59:59.000Z

95

How to Fit simply Soil Mechanics Behaviour with Incremental Modelling and to Describe Drained Cyclic Behaviours  

E-Print Network (OSTI)

It has been proposed recently a new incremental modelling to describe the mechanics of soil. It is based on two parameters called the pseudo Young modulus E=1/Co and the pseudo Poisson coefficient n, which both evolve during compression. Evolution of n is known since it shall fit the Rowe's law of dilatancy, but Co has to be evaluated from experiment. In this paper we proposed a way to evaluate the Co variation from other mechanical modelling. The way cyclic behaviour of drained sample can be modelled is also described.

P. Evesque

2005-07-04T23:59:59.000Z

96

Lifetime Prediction for Supercapacitor-powered Wireless Sensor Nodes  

E-Print Network (OSTI)

Lifetime Prediction for Supercapacitor-powered Wireless Sensor Nodes Christian Renner, J step towards reaching this goal: It explores discharging-characteristics of supercapacitors, discusses-ion polymers, supercapacitors can last for 10 years or even more. Superca- pacitors do not need a complex

Turau, Volker

97

An Experimental and Numerical Investigation of the Steady State Forces in Single Incremental Sheet Forming  

E-Print Network (OSTI)

Incremental sheet forming process is a relatively new method of forming which is increasingly being used in the industry. Complex shapes can be manufactured using this method and the forming operation doesn't require any dies. High strains of over 300 % can also be achieved. Incremental sheet forming method is used to manufacture many different components presently. Prototype examples include car headlights, tubs, train body panels and medical products. The work done in the thesis deals with the prediction of the steady state forces acting on the tool during forming. Prediction of forces generated would help to design the machine against excessive vibrations. It would help the user to protect the tool and the material blank from failure. An efficient design ensures that the tool would not get deflected out of its path while forming, improving the accuracy of the finished part. To study the forces, experiments were conducted by forming pyramid and cone shapes. An experimental arrangement was set up and experimental data was collected using a data acquisition system. The effect that the various process parameters, like the thickness of the sheet, wall angle of the part and tool diameter had on the steady state force were studied. A three dimensional model was developed using commercial finite element software ABAQUS using a new modeling technique to simulate the deformation of the sheet metal blank during incremental sheet forming. The steady state forces generated for any shape, with any set of parameters used, could be predicted using the numerical model. The advantage of having a numerical model is that the forces can be predicted without doing experiments. The model was used to predict the steady state forces developed during forming of pyramid and cone shapes. The results were compared and were seen to be reasonably close to the experimental results. Later, the numerical model was validated by forming arbitrary shapes and comparing the value obtained from simulations to the value of the measured steady state forces. The results obtained from the numerical model were seen to match very well with the experimental forces for the new shapes. The numerical model developed using the new technique was seen to predict forces to a reasonable extent with less computational time as compared to the models currently available.

Nair, Mahesh

2011-08-01T23:59:59.000Z

98

Online Prediction of Battery Lifetime for Embedded and Mobile Devices  

E-Print Network (OSTI)

This paper presents a novel, history-based, statistical technique for online battery lifetime prediction. The approach first takes a one-time, full cycle, voltage measurement of a constant load, and uses it to transform the partial voltage curve of the current workload into a form with robust predictability. Based on the transformed history curve, we apply a statistical method to make a lifetime prediction. We investigate the performance of the implementation of our approach on a widely used mobile device (HP iPAQ) running Linux, and compare it to two similar battery prediction technologies: ACPI and Smart Battery. We employ twenty-two constant and variable workloads to verify the effcacy of our approach. Our results show that this approach is efficient, accurate, and able to adapt to different systems and batteries easily.

Ye Wen; Rich Wolski; Chandra Krintz

2003-01-01T23:59:59.000Z

99

Public Affairs Office: Livermore Lab Physicist Dates Lifetime of Solar  

NLE Websites -- All DOE Office Websites (Extended Search)

Dating the Solar System: Where Were You When the Solar System Was Being Formed? Dating the Solar System: Where Were You When the Solar System Was Being Formed? Chemistry & Materials Science Directorate, LLNL Chronology of the early Solar System from chondrule-bearing calcium-aluminium-rich inclusions Nature, April 21, 2005 Building Planets at PSI: The Origin of the Solar System Planetary Science Institute Social Media Logos Follow LLNL on YouTube Subscribe to LLNL's RSS feed Follow LLNL on Facebook Follow LLNL on Twitter Follow LLNL on Flickr Contact: Anne M. Stark Phone: (925) 422-9799 E-mail: stark8@llnl.gov FOR IMMEDIATE RELEASE April 20, 2005 NR-05-04-02 Livermore Lab physicist dates lifetime of solar nebula at two million years LIVERMORE, Calif. - The oxygen and magnesium content of some of the oldest objects in the universe are giving clues to the lifetime of the

100

A Measurement of the D+(s) lifetime  

SciTech Connect

A high statistics measurement of the D{sub s}{sup +} lifetime from the Fermilab fixed-target FOCUS photoproduction experiment is presented. They describe the analysis of the two decay modes, D{sub s}{sup +} {yields} {phi}(1020){pi}{sup +} and D{sub s}{sup +} {yields} {bar K}*(892){sup 0}K{sup +}, used for the measurement. The measured lifetime is 507.4 {+-} 5.5(stat.) {+-} 5.1(syst.) is using 8961 {+-} 105 D{sub s}{sup +} {yields} {phi}(1020){pi}{sup +} and 4680 {+-} 90 D{sub s}{sup +} {yields} {bar K}*(892){sup 0} K{sup +} decays. This is a significant improvement over the present world average.

Link, J.M.; Yager, P.M.; /UC, Davis; Anjos, J.C.; Bediaga, I.; Castromonte, C.; Machado, A.A.; Magnin, J.; Massafferi, A.; de Miranda, J.M.; Pepe, I.M.; Polycarpo, E.; dos Reis, A.C.; /Rio de Janeiro, CBPF; Carrillo, S.; Casimiro, E.; Cuautle, E.; Sanchez-Hernandez, A.; Uribe, C.; Vazquez, F.; /CINVESTAV, IPN; Agostino, L.; Cinquini, L.; Cumalat, J.P. /Colorado U. /Fermilab /Frascati /Guanajuato U. /Illinois U., Urbana /Indiana U. /Korea U. /Kyungpook Natl. U. /INFN, Milan /Milan U. /North Carolina U. /Pavia U. /INFN, Pavia /Rio de Janeiro, Pont. U. Catol. /Puerto Rico U., Mayaguez /South Carolina U. /Tennessee U. /Vanderbilt U. /Wisconsin U., Madison

2005-04-01T23:59:59.000Z

Note: This page contains sample records for the topic "incremental lifetime cancer" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


101

Hot ion buildup and lifetime in LITE. Final report  

DOE Green Energy (OSTI)

An experimental investigation of hot ion buildup and lifetime in a small scale mirror device (LITE) is described. Hot ions were produced by 27 kV neutral beam injection into laser produced LiH plasmas and H plasmas produced by a washer gun. Hot H ion (12 kV) densities of approx. = 10/sup 12/ cm/sup -3/ were produced with the LiH target plasmas and densities an order of magnitude lower were produced with the washer gun target plasmas. Hot ion dominant plasmas were not achieved in LITE. The experimental measurements and subsequent analysis using numerical models of the plasma buildup indicate that in small, unshielded mirror plasmas, careful control must be maintained over the transient background gas density in the vicinity of the plasma surface. The hot ion lifetime in LITE was set by the transient cold neutral background resulting from the washer gun of reflux from the target plasma striking the adjacent surfaces.

Not Available

1978-09-01T23:59:59.000Z

102

Pressurized Water Reactor AgInCd Control Rod Lifetime  

Science Conference Proceedings (OSTI)

Swelling of the lower end tip of AgInCd (AIC) absorber rods is one of the lifetime limiting phenomena for PWR control rods. Understanding the relationship between swelling and accumulated fluence is crucial to predicting the service life of these components. This report presents the initial results and analyses from a control rod absorber research program led by the EPRI Fuel Reliability Program, in close collaboration with Westinghouse Electric Company and AREVA NP. The goals of the program are to chara...

2009-08-27T23:59:59.000Z

103

Lifetime statistics of quantum chaos studied by a multiscale analysis  

SciTech Connect

In a series of pump and probe experiments, we study the lifetime statistics of a quantum chaotic resonator when the number of open channels is greater than one. Our design embeds a stadium billiard into a two dimensional photonic crystal realized on a silicon-on-insulator substrate. We calculate resonances through a multiscale procedure that combines energy landscape analysis and wavelet transforms. Experimental data is found to follow the universal predictions arising from random matrix theory with an excellent level of agreement.

Di Falco, A.; Krauss, T. F. [School of Physics and Astronomy, University of St. Andrews, North Haugh, St. Andrews, KY16 9SS (United Kingdom); Fratalocchi, A. [PRIMALIGHT, Faculty of Electrical Engineering, Applied Mathematics and Computational Science, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900 (Saudi Arabia)

2012-04-30T23:59:59.000Z

104

Lifetime of high-k gate dielectrics and analogy with strength of quasibrittle structures  

E-Print Network (OSTI)

The two-parameter Weibull distribution has been widely adopted to model the lifetime statistics of dielectric breakdown under constant voltage, but recent lifetime testing for high-k gate dielectrics has revealed a systematic ...

Le, Jia-Liang

105

Using Remaining Battery lifetime information and Relaying to decrease Outage Probability of a Mobile  

E-Print Network (OSTI)

Using Remaining Battery lifetime information and Relaying to decrease Outage Probability is to demonstrate that by employing relaying and using the remaining battery lifetime information of Mobile is determined based on the remaining battery lifetime of the MT. We assume a linear relationship between

Singh, Suresh

106

From link dynamics to path lifetime and packet-length optimization in MANETs  

Science Conference Proceedings (OSTI)

We present an analytical framework and statistical models to accurately characterize the lifetime of a wireless link and multi-hop paths in mobile ad hoc networks (MANET). We show that the lifetimes of links and paths can be computed through a two-state ... Keywords: Analytical mobility modeling, Link dynamics, Markov model, Optimal information segmentation, Path lifetime

Xianren Wu; Hamid R. Sadjadpour; J. J. Garcia-Luna-Aceves

2009-07-01T23:59:59.000Z

107

Constrained multiple deployment problem in wireless sensor networks with guaranteed lifetimes  

Science Conference Proceedings (OSTI)

We aimed to deploy wireless sensor networks with guaranteed lifetimes for outdoor monitoring projects. The provision of a guaranteed lifetime has rarely been studied in previous deployment problems. The use of battery packs as the power source for sensors ... Keywords: Deployment problem, Guaranteed lifetime, Sensor network

Chun-Han Lin; Chung-Ta King; Ting-Yi Chen

2011-02-01T23:59:59.000Z

108

THE POLITICS OF NON-INCREMENTAL SCHOOL FINANCE REFORM: A CASE STUDY ANALYSIS OF VERMONT'S ACT 60 AS A TEST OF MAZZONI'S ARENA MODEL.  

E-Print Network (OSTI)

??This research, grounded in political theory, had two major purposes: 1) to explain a case of non-incremental policy change within the realm of school finance… (more)

Curtis, Kimberly Anne

2011-01-01T23:59:59.000Z

109

Taxonomic knowledge structure discovery from imagery-based data using the neural associative incremental learning (NAIL) algorithm  

Science Conference Proceedings (OSTI)

An important component of higher level fusion is knowledge discovery. One form of knowledge is a set of relationships between concepts. This paper addresses the automated discovery of ontological knowledge representations such as taxonomies/thesauri ... Keywords: Associative learning, Incremental learning, Information fusion, Knowledge structure, Multi-target classification, Ontology learning, Taxonomy

Bradley J. Rhodes

2007-07-01T23:59:59.000Z

110

Recombination Lifetimes Using the RCPCD Technique: Comparison with Other Methods  

DOE Green Energy (OSTI)

The theory and operation of the resonance-coupled photoconductive decay (RCPCD) technique is described. Examples are presented of data measured on a wide variety of sample types. The RCPCD technique has been applied to a variety of wafer and thin-film materials. Using this technique, we can measure recombination lifetime over at least three decades of injection level. We can also measure relative values of minority-carrier mobility and diffusion length. By scanning the excitation wavelength, we can measure spectral response and photoconductive excitation spectra. Deep-level impurities have been detected by several variations of RCPCD.

Ahrenkiel, R.K.; Johnston, S.W.; Dashdorj, J.

2005-01-01T23:59:59.000Z

111

Electron Beam Polarization Measurement Using Touschek Lifetime Technique  

SciTech Connect

Electron beam loss due to intra-beam scattering, the Touschek effect, in a storage ring depends on the electron beam polarization. The polarization of an electron beam can be determined from the difference in the Touschek lifetime compared with an unpolarized beam. In this paper, we report on a systematic experimental procedure recently developed at Duke FEL laboratory to study the radiative polarization of a stored electron beam. Using this technique, we have successfully observed the radiative polarization build-up of an electron beam in the Duke storage ring, and determined the equilibrium degree of polarization and the time constant of the polarization build-up process.

Sun, Changchun; /Duke U., DFELL; Li, Jingyi; /Duke U., DFELL; Mikhailov, Stepan; /Duke U., DFELL; Popov, Victor; /Duke U., DFELL; Wu, Wenzhong; /Duke U., DFELL; Wu, Ying; /Duke U., DFELL; Chao, Alex; /SLAC; Xu, Hong-liang; /Hefei, NSRL; Zhang, Jian-feng; /Hefei, NSRL

2012-08-24T23:59:59.000Z

112

Determination of the b_s lifetime using hadronic decays  

SciTech Connect

The authors present a measurement of the B{sub s}{sup 0} meson lifetime using fully and partially reconstructed hadronic decays B{sub s}{sup 0} {yields} D{sub s}{sup -} {pi}{sup +}(X) followed by D{sub s}{sup -} {yields} {phi}{pi}{sup -}. The data sample was recorded with the CDF II detector at the Fermilab Tevatron and corresponds to an integrated luminosity of 1.3 fb{sup -1} from p{bar p} collisions at {radical}s = 1.96 TeV.

Deisher, A.J.; /LBL, Berkeley

2008-07-01T23:59:59.000Z

113

Impact of incremental changes in meteorology on thermal compliance and power system operations  

Science Conference Proceedings (OSTI)

The sensitivity of the TVA reservoir and power supply systems to extreme meteorology was evaluated using a series of mathematical models to simulate the relationship between incremental changes in meteorology, associated changes in water temperature, and power plant generation. Single variable analysis techniques were applied at selected TVA facilities for representative average and extreme weather conditions. In the analysis, base case simulations were first conducted for each representative year using observed meteorology (i.e., the no change condition). The impacts of changes in meteorology were subsequently analyzed by uniformly constant at their respective base case values. Project results are generally presented in terms of deviations from base case conditions for each representative year. Based on an analysis of natural flow and air temperature patterns at Chickamauga Dam, 1974 was selected to represent extreme cold-wet conditions; 1965 as reflecting average conditions; and 1986 as an example of an extremely hot-dry year. The extreme years (i.e., 1974 and 1986) were used to illustrate sensitivities beyond historical conditions; while the average year provided a basis for comparison. Observed reservoir conditions, such as inflows, dam releases, and reservoir elevations for each representative year, were used in the analysis and were assumed to remain constant in all simulations. Therefore, the Lake Improvement Plan (which was implemented in 1991) and its consequent effects on reservoir operations were not incorporated in the assessment. In the model simulations, computed water temperatures were based on vertically well-mixed conditions in the reservoirs.

Miller, B.A.; Alavian, V.; Bender, M.D. [and others

1992-02-01T23:59:59.000Z

114

Lifetime measurements in the transitional nucleus {sup 138}Gd  

Science Conference Proceedings (OSTI)

Lifetime measurements have been made in the ground-state band of the transitional nucleus {sup 138}Gd from coincidence recoil-distance Doppler-shift data. {sup 138}Gd nuclei were produced using the {sup 106}Cd ({sup 36}Ar, 2p2n) reaction with a beam energy of 190 MeV. Reduced transition probabilities have been extracted from the lifetime data collected with the Koeln plunger placed at the target position of the JUROGAM-II array. The B(E2) values have been compared with predictions from X(5) critical-point calculations, which describe the phase transition between vibrational and axially symmetric nuclear shapes, as well as with IBM-1 calculations at the critical point. While the excitation energies in {sup 138}Gd are consistent with X(5) predictions, the large uncertainties associated with the measured B(E2) values cannot preclude vibrational and rotational contributions to the low-lying structure of {sup 138}Gd. Although experimental knowledge for the low-lying {gamma} and {beta}-vibrational bands in {sup 138}Gd is limited, potential-energy surface calculations suggest an increase in {gamma} softness in the ground-state band. In order to more fully account for the effects of {gamma} softness, the X(5) and IBM-1 calculations need to be extended to include the {gamma} degree of freedom for {sup 138}Gd.

Procter, M. G.; Cullen, D. M.; Taylor, M. J. [Schuster Laboratory, University of Manchester, Manchester, M13 9PL (United Kingdom); Ruotsalainen, P.; Grahn, T.; Greenlees, P. T.; Hauschild, K.; Jakobsson, U.; Jones, P. M.; Julin, R.; Juutinen, S.; Ketelhut, S.; Lopez-Martens, A.; Leino, M.; Nieminen, P.; Peura, P.; Rahkila, P.; Rinta-Antilla, S.; Sandzelius, M.; Saren, J. [Department of Physics, University of Jyvaeskylae, FIN-40014 Jyvaeskylae (Finland)

2011-08-15T23:59:59.000Z

115

Extending the lifetime of fuel cell based hybrid systems  

E-Print Network (OSTI)

Fuel cells are clean power sources that have much higher energy densities and lifetimes compared to batteries. However, fuel cells have limited load following capabilities and cannot be efficiently utilized if used in isolation. In this work, we consider a hybrid system where a fuel cell based hybrid power source is used to provide power to a DVFS processor. The hybrid power source consists of a room temperature fuel cell operating as the primary power source and a Li-ion battery (that has good load following capability) operating as the secondary source. Our goal is to develop polices to extend the lifetime of the fuel cell based hybrid system. First, we develop a charge based optimization framework which minimizes the charge loss of the hybrid system (and not the energy consumption of the DVFS processor). Next, we propose a new algorithm to minimize the charge loss by judiciously scaling the load current. We compare the performance of this algorithm with one that has been optimized for energy, and demonstrate its superiority. Finally, we evaluate the performance of the hybrid system under different system configurations and show how to determine the best combination of fuel cell size and battery capacity for a given embedded application.

Jianli Zhuo; Chaitali Chakrabarti; Naehyuck Chang; Sarma Vrudhula

2006-01-01T23:59:59.000Z

116

THE LIFETIME AND POWERS OF FR IIs IN GALAXY CLUSTERS  

Science Conference Proceedings (OSTI)

We have identified and studied a sample of 151 FR IIs found in brightest cluster galaxies (BCGs) in the MaxBCG cluster catalog with data from FIRST and NVSS. We have compared the radio luminosities and projected lengths of these FR IIs to the projected length distribution of a range of mock catalogs generated by an FR II model and estimate the FR II lifetime to be 1.9 Multiplication-Sign 10{sup 8} yr. The uncertainty in the lifetime calculation is a factor of two, primarily due to uncertainties in the intracluster medium (ICM) density and the FR II axial ratio. We furthermore measure the jet power distribution of FR IIs in BCGs and find that it is well described by a log-normal distribution with a median power of 1.1 Multiplication-Sign 10{sup 37} W and a coefficient of variation of 2.2. These jet powers are nearly linearly related to the observed luminosities, and this relation is steeper than many other estimates, although it is dependent on the jet model. We investigate correlations between FR II and cluster properties and find that galaxy luminosity is correlated with jet power. This implies that jet power is also correlated with black hole mass, as the stellar luminosity of a BCG should be a good proxy for its spheroid mass and therefore the black hole mass. Jet power, however, is not correlated with cluster richness, nor is FR II lifetime strongly correlated with any cluster properties. We calculate the enthalpy of the lobes to examine the impact of the FR IIs on the ICM and find that heating due to adiabatic expansion is too small to offset radiative cooling by a factor of at least six. In contrast, the jet power is approximately an order of magnitude larger than required to counteract cooling. We conclude that if feedback from FR IIs offsets cooling of the ICM, then heating must be primarily due to another mechanism associated with FR II expansion.

Antognini, Joe; Bird, Jonathan; Martini, Paul, E-mail: antognini@astronomy.ohio-state.edu, E-mail: bird@astronomy.ohio-state.edu, E-mail: martini@astronomy.ohio-state.edu [Department of Astronomy, Ohio State University, 140 W 18th Avenue, Columbus, OH 43210 (United States)

2012-09-10T23:59:59.000Z

117

Enhancement of the steady state minority carrier lifetime in HgCdTe photodiode using ECR plasma hydrogenation  

Science Conference Proceedings (OSTI)

Keywords: HgCdTe, diffusion length, field effect transistor, hydrogenation, lifetime, mobility, photodiode

Han Jung; Hee Chul Lee; Choong-Ki Kim

1996-08-01T23:59:59.000Z

118

Microstructure, morphology and lifetime of armored bubbles exposed to surfactants  

E-Print Network (OSTI)

We report the behavior of particle-stabilized bubbles (armored bubbles) when exposed to various classes and concentrations of surfactants. The bubbles are non-spherical due to the jamming of the particles on the interface and are stable to dissolution prior to the addition of surfactant. We find that the dissolving bubbles exhibit distinct morphological, microstructural, and lifetime changes, which correlate with the concentration of surfactant employed. For low concentrations of surfactant an armored bubble remains non-spherical while dissolving, while for concentrations close to and above the surfactant CMC a bubble reverts to a spherical shape before dissolving. We propose a microstructural interpretation, supported by our experimental observations of particle dynamics on the bubble interface, that recognizes the role of interfacial jamming and stresses in particle stabilization and surfactant-mediated destabilization of armored bubbles.

Anand Bala Subramaniam; Cecile Mejean; Manouk Abkarian; Howard A. Stone

2006-02-16T23:59:59.000Z

119

Measurements of ultracold neutron lifetimes in solid deuterium  

E-Print Network (OSTI)

We present the first measurements of the survival time of ultracold neutrons (UCNs) in solid deuterium SD2. This critical parameter provides a fundamental limitation to the effectiveness of superthermal UCN sources that utilize solid ortho-deuterium as the source material. Superthermal UCN sources offer orders of magnitude improvement in the available densities of UCNs, and are of great importance to fundamental particle-physics experiments such as searches for a static electric dipole moment and lifetime measurements of the free neutron. These measurements are performed utilizing a SD2 source coupled to a spallation source of neutrons, providing a demonstration of UCN production in this geometry and permitting systematic studies of the influence of thermal up-scatter and contamination with para-deuterium on the UCN survival time.

C. L. Morris; J. M. Anaya; T. J. Bowles; B. W. Filippone; P. Geltenbort; R. E. Hill; M. Hino; S. Hoedl; G. E. Hogan; T. M. Ito; T. Kawai; K. Kirch; S. K. Lamoreaux; C. -Y. Liu; M. Makela; L. J. Marek; J. W. Martin; R. N. Mortensen; A. Pichlmaier; A. Saunders; S. J. Seestrom; D. Smith; W. Teasdale; B. Tipton; M. Utsuro; A. R. Young; J. Yuan

2001-09-27T23:59:59.000Z

120

Extending lifetime of portable systems by battery scheduling  

E-Print Network (OSTI)

Multi-battery power supplies are becoming popular in electronic appliances of the latest generations, due to economical and manufacturing constraints. Unfortunately, a partitioned battery subsystem is not able to deliver the same amount of charge as a monolithic battery with the same total capacity. In this paper, we de ne the concept of battery scheduling, we investigate policies for solving the problem of optimal charge delivery, and we study the relationship of such policies with di erent con gurations of the battery subsystem. Results, obtained for di erent workloads, demonstrate that the choice of the proper scheduling can make, in the best case, system lifetime as close as 1 % of that guaranteed by a monolithic battery of equal capacity. 1

L. Benini; G. Castelli Z; A. Macii Z

2001-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "incremental lifetime cancer" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


121

Effects of Neutron Irradiation on Positron Lifetime and Micro-Vicker ...  

Science Conference Proceedings (OSTI)

Aug 1, 1999 ... Effects of Neutron Irradiation on Positron Lifetime and Micro-Vicker Hardness of Fe-Cu Model Alloys and Reactor Pressure Vessel Steel

122

LIFETIME PREDICTION FOR MODEL 9975 O-RINGS IN KAMS  

SciTech Connect

The Savannah River Site (SRS) is currently storing plutonium materials in the K-Area Materials Storage (KAMS) facility. The materials are packaged per the DOE 3013 Standard and transported and stored in KAMS in Model 9975 shipping packages, which include double containment vessels sealed with dual O-rings made of Parker Seals compound V0835-75 (based on Viton{reg_sign} GLT). The outer O-ring of each containment vessel is credited for leaktight containment per ANSI N14.5. O-ring service life depends on many factors, including the failure criterion, environmental conditions, overall design, fabrication quality and assembly practices. A preliminary life prediction model has been developed for the V0835-75 O-rings in KAMS. The conservative model is based primarily on long-term compression stress relaxation (CSR) experiments and Arrhenius accelerated-aging methodology. For model development purposes, seal lifetime is defined as a 90% loss of measurable sealing force. Thus far, CSR experiments have only reached this target level of degradation at temperatures {ge} 300 F. At lower temperatures, relaxation values are more tolerable. Using time-temperature superposition principles, the conservative model predicts a service life of approximately 20-25 years at a constant seal temperature of 175 F. This represents a maximum payload package at a constant ambient temperature of 104 F, the highest recorded in KAMS to date. This is considered a highly conservative value as such ambient temperatures are only reached on occasion and for short durations. The presence of fiberboard in the package minimizes the impact of such temperature swings, with many hours to several days required for seal temperatures to respond proportionately. At 85 F ambient, a more realistic but still conservative value, bounding seal temperatures are reduced to {approx}158 F, with an estimated seal lifetime of {approx}35-45 years. The actual service life for O-rings in a maximum wattage package likely lies higher than the estimates due to the conservative assumptions used for the model. For lower heat loads at similar ambient temperatures, seal lifetime is further increased. The preliminary model is based on several assumptions that require validation with additional experiments and longer exposures at more realistic conditions. The assumption of constant exposure at peak temperature is believed to be conservative. Cumulative damage at more realistic conditions will likely be less severe but is more difficult to assess based on available data. Arrhenius aging behavior is expected, but non-Arrhenius behavior is possible. Validation of Arrhenius behavior is ideally determined from longer tests at temperatures closer to actual service conditions. CSR experiments will therefore continue at lower temperatures to validate the model. Ultrasensitive oxygen consumption analysis has been shown to be useful in identifying non-Arrhenius behavior within reasonable test periods. Therefore, additional experiments are recommended and planned to validate the model.

Hoffman, E.; Skidmore, E.

2009-11-24T23:59:59.000Z

123

Accelerated lifetime estimation of thermosonic Cu ball bonds on Al metallization  

Science Conference Proceedings (OSTI)

In this study a fast mechanical shear fatigue test technique for the quality assessment of thermosonic ball bonded interconnects was developed to estimate their lifetime behavior. The micro-interconnects were subjected to cyclic shear stress using a ... Keywords: Cu/Al Ball bond, Fatigue, Fracture mechanics, Lifetime, Microelectronic interconnects

A. Lassnig, W. Trasischker, G. Khatibi, B. Weiss, M. Nelhiebel, R. Pelzer

2013-06-01T23:59:59.000Z

124

Extending the lifetime of media recorders constrained by battery and flash memory size  

Science Conference Proceedings (OSTI)

The lifetime of a stand-alone media recorder is a function of both the battery size and flash memory size. In this paper, we present a power management framework for media recorders that significantly enhances their lifetime while minimizing the flash ... Keywords: dynamic voltage scaling, multimedia, passive voltage scaling

Younghyun Kim; Youngjin Cho; Naehyuck Chang; Chaitali Chakrabarti; Nam Ik Cho

2008-08-01T23:59:59.000Z

125

A Proactive Wearout Recovery Approach for Exploiting Microarchitectural Redundancy to Extend Cache SRAM Lifetime  

Science Conference Proceedings (OSTI)

Microarchitectural redundancy has been proposed as a means of improving chip lifetime reliability. It is typically used in a reactive way, allowing chips to maintain operability in the presence of failures by detecting and isolating, correcting, and/or ... Keywords: lifetime reliability, microarchitectural redundancy, proactive approach, wearout recovery

Jeonghee Shin; Victor Zyuban; Pradip Bose; Timothy M. Pinkston

2008-06-01T23:59:59.000Z

126

Deployment guidelines for achieving maximum lifetime and avoiding energy holes in sensor network  

Science Conference Proceedings (OSTI)

The demand for maximum network lifetime in many mission-critical applications of wireless sensor networks motivates the great significance to deploy as few sensors as possible to achieve the expected network performance. In this paper, we first characterize ... Keywords: Adjustable transmission range, Energy-hole, Network lifetime, Node deployment, Wireless sensor network

Anfeng Liu; Xin Jin; Guohua Cui; Zhigang Chen

2013-05-01T23:59:59.000Z

127

Optimizing lifetime for continuous data aggregation with precision guarantees in wireless sensor networks  

Science Conference Proceedings (OSTI)

This paper exploits the tradeoff between data quality and energy consumption to extend the lifetime of wireless sensor networks. To obtain an aggregate form of sensor data with precision guarantees, the precision constraint is partitioned and allocated ... Keywords: data accuracy, data aggregation, energy efficiency, network lifetime, sensor network

Xueyan Tang; Jianliang Xu

2008-08-01T23:59:59.000Z

128

Microsoft Word - Evaluation of an Incremental Ventilation Energy Model for Estimating Impacts of Air Sealing and Mechanical Ventilation_Final2.docx  

NLE Websites -- All DOE Office Websites (Extended Search)

XXXXX | Logue et al., Evaluation of an Incremental Ventilation Energy Model for Estimating XXXXX | Logue et al., Evaluation of an Incremental Ventilation Energy Model for Estimating Impacts of Air Sealing and Mechanical Ventilation 1 Evaluation of an Incremental Ventilation Energy Model for Estimating Impacts of Air Sealing and Mechanical Ventilation Jennifer M. Logue, William J. N. Turner, Iain S. Walker, and Brett C. Singer Environmental Energy Technologies Division June 2012 LBNL-5796E LBNL-XXXXX | Logue et al., Evaluation of an Incremental Ventilation Energy Model for Estimating Impacts of Air Sealing and Mechanical Ventilation 2 Disclaimer This document was prepared as an account of work sponsored by the United States Government. While this document is believed to contain correct information, neither the United States Government nor any agency thereof, nor The Regents of the University of California, nor

129

Optimal Reversible Annuities to Minimize the Probability of Lifetime Ruin  

E-Print Network (OSTI)

We find the minimum probability of lifetime ruin of an investor who can invest in a market with a risky and a riskless asset and who can purchase a reversible life annuity. The surrender charge of a life annuity is a proportion of its value. Ruin occurs when the total of the value of the risky and riskless assets and the surrender value of the life annuity reaches zero. We find the optimal investment strategy and optimal annuity purchase and surrender strategies in two situations: (i) the value of the risky and riskless assets is allowed to be negative, with the imputed surrender value of the life annuity keeping the total positive; or (ii) the value of the risky and riskless assets is required to be non-negative. In the first case, although the individual has the flexiblity to buy or sell at any time, we find that the individual will not buy a life annuity unless she can cover all her consumption via the annuity and she will never sell her annuity. In the second case, the individual surrenders just enough annuity income to keep her total assets positive. However, in this second case, the individual’s annuity purchasing strategy depends on the size of the proportional surrender charge. When the charge is large enough, the individual will not buy a life annuity unless she can cover all her consumption, the so-called safe level. When the charge is small enough, the individual will buy a life annuity at a wealth lower than this safe level. Key words. Life annuities, retirement, optimal investment, stochastic control, freeboundary problem 1

Ting Wang; Virginia R. Young

2009-01-01T23:59:59.000Z

130

Los Alamos National Laboratory W76 Pit Tube Lifetime Study  

SciTech Connect

A metallurgical study was requested as part of the Los Alamos National Laboratory (LANL) W76-1 life-extension program (LEP) involving a lifetime analysis of type 304 stainless steel pit tubes subject to repeat bending loads during assembly and disassembly operations at BWXT/Pantex. This initial test phase was completed during the calendar years of 2004-2006 and the report not issued until additional recommended tests could be performed. These tests have not been funded to this date and therefore this report is considered final. Tubes were reportedly fabricated according to Rocky Flats specification P14548 - Seamless Type 304 VIM/VAR Stainless Steel Tubing. Tube diameter was specified as 0.125 inches and wall thickness as 0.028 inches. A heat treat condition is not specified and the hardness range specification can be characteristic of both 1/8 and 1/4 hard conditions. Properties of all tubes tested were within specification. Metallographic analysis could not conclusively determine a specified limit to number of bends allowable. A statistical analysis suggests a range of 5-7 bends with a 99.95% confidence limit. See the 'Statistical Analysis' section of this report. The initial phase of this study involved two separate sets of test specimens. The first group was part of an investigation originating in the ESA-GTS [now Gas Transfer Systems (W-7) Group]. After the bend cycle test parameters were chosen (all three required bends subjected to the same amount of bend cycles) and the tubes bent, the investigation was transferred to Terri Abeln (Metallurgical Science and Engineering) for analysis. Subsequently, another limited quantity of tubes became available for testing and were cycled with the same bending fixture, but with different test parameters determined by T. Abeln.

Abeln, Terri G. [Los Alamos National Laboratory

2012-04-25T23:59:59.000Z

131

First working group meeting on the minority carrier diffusion length/lifetime measurement: Results of the round robin lifetime/diffusion length tests  

DOE Green Energy (OSTI)

As was noted in the cover letter that accompanied the samples, the eleven bare silicon samples were from various manufacturers. Table I lists the codes for the samples and the manufacturer of each sample. It also notes if the sample was single or poly-crystalline. The samples had been polished on one side before being sent out for measurements, but no further processing was done. The participants of the study were asked to measure either the lifetime or diffusion length of each of the samples using their standard procedure. Table II shows the experimental conditions used by the groups who measured diffusion length. All the diffusion length measurements were performed using the Surface Photovoltage method (SPV). Table M shows the experimental conditions for the lifetime measurements. All the lifetime measurements were made using the Photoconductance Decay method (PCD) under low level injection. These tables show the diameter of the spot size used during the measurement (the effective sampling area), the locations where measurements were taken, and the number of measurements taken at each location. Table N shows the results of the measurements. The table is divided into diffusion length and lifetime measurements for each sample. The values listed are the average values reported by each group. One of the immediate artifacts seen in the data is the large variation in the lifetime measurements. The values from MIT and Mobil are generally close. However, the measurements from NCSU are typically an order of magnitude lower.

Cudzinovic, M.; Sopori, B. [comp.

1995-11-01T23:59:59.000Z

132

Stability and Lifetime of K-CoMoSx Mixed Alcohol Catalysts  

SciTech Connect

Researchers have studied sulfide-type catalysts for the production of mixed alcohols from synthesis gas for several decades. Despite many advances in the art, these processes are not yet commercial, due in large part to mediocre economics and the added risk associated with uncertainty in catalyst lifetime. This talk will outline some recent studies in the lifetime and stability of K-CoMoSx-type mixed alcohol catalysts. Specifically, studies of long term operation (> 3000h), sulfiding agents, simulated methanol recycle, and morphology (probed via XRD and XPS) will be discussed, with the conclusion that these materials are likely to exhibit acceptable lifetimes in continuous operation.

Hensley, J. E.; Ruddy, D.; Schaidle, J.; Ferrell, J.; Thibodeaux, J.

2013-01-01T23:59:59.000Z

133

New Tool Quantitatively Maps Minority-Carrier Lifetime of Multicrystalline Silicon Bricks (Fact Sheet)  

DOE Green Energy (OSTI)

NREL's new imaging tool could provide manufacturers with insight on their processes. Scientists at the National Renewable Energy Laboratory (NREL) have used capabilities within the Process Development and Integration Laboratory (PDIL) to generate quantitative minority-carrier lifetime maps of multicrystalline silicon (mc-Si) bricks. This feat has been accomplished by using the PDIL's photoluminescence (PL) imaging system in conjunction with transient lifetime measurements obtained using a custom NREL-designed resonance-coupled photoconductive decay (RCPCD) system. PL imaging can obtain rapid high-resolution images that provide a qualitative assessment of the material lifetime-with the lifetime proportional to the pixel intensity. In contrast, the RCPCD technique provides a fast quantitative measure of the lifetime with a lower resolution and penetrates millimeters into the mc-Si brick, providing information on bulk lifetimes and material quality. This technique contrasts with commercially available minority-carrier lifetime mapping systems that use microwave conductivity measurements. Such measurements are dominated by surface recombination and lack information on the material quality within the bulk of the brick. By combining these two complementary techniques, we obtain high-resolution lifetime maps at very fast data acquisition times-attributes necessary for a production-based diagnostic tool. These bulk lifetime measurements provide manufacturers with invaluable feedback on their silicon ingot casting processes. NREL has been applying the PL images of lifetime in mc-Si bricks in collaboration with a U.S. photovoltaic industry partner through Recovery Act Funded Project ARRA T24. NREL developed a new tool to quantitatively map minority-carrier lifetime of multicrystalline silicon bricks by using photoluminescence imaging in conjunction with resonance-coupled photoconductive decay measurements. Researchers are not hindered by surface recombination and can look deeper into the material to map bulk lifetimes. The tool is being applied to silicon bricks in a project collaborating with a U.S. photovoltaic industry partner. Photovoltaic manufacturers can use the NREL tool to obtain valuable feedback on their silicon ingot casting processes.

Not Available

2011-11-01T23:59:59.000Z

134

Increasing network lifetime in an energy-constrained wireless sensor network  

Science Conference Proceedings (OSTI)

Energy in wireless sensor networks is a scarce resource, therefore an energy-efficient mechanism is required to increase the network lifetime. In this paper, we study the problem of optimal power allocation, taking into account the estimation of the ...

Said El Abdellaoui; Mérouane Debbah; Youssef Fakhri; Driss Aboutajdine

2013-03-01T23:59:59.000Z

135

Modeling Minority-Carrier Lifetime Techniques That Use Transient Excess-Carrier Decay: Preprint  

DOE Green Energy (OSTI)

Lifetime spectroscopy is a valuable tool for the characterization of PV materials. This paper combines modeling and experimental results to illustrate the injection-level dependent response of three transient excess-carrier decay techniques.

Johnston, S. W.; Berman, G. M.; Ahrenkiel, R. K.

2008-05-01T23:59:59.000Z

136

New Accelerated Testing and Lifetime Modeling Methods Promise Faster Development of More Durable MEAs  

DOE Green Energy (OSTI)

For the successful commercialization of fuel cell technology, it is imperative that membrane electrode assembly (MEA) durability is understood and quantified. MEA lifetimes of 40,000 hours remain a key target for stationary power applications. Since it is impractical to wait 40,000 hours for durability results, it is critical to learn as much information as possible in as short a time period as possible to determine if an MEA sample will survive past its lifetime target. Consequently, 3M has utilized accelerated testing and statistical lifetime modeling tools to develop a methodology for evaluating MEA lifetime. Construction and implementation of a multi-cell test stand have allowed for multiple accelerated tests and stronger statistical data for learning about durability.

Pierpont, D. M.; Hicks, M. T.; Turner, P. L.; Watschke, T. M.

2005-11-01T23:59:59.000Z

137

Lifetime measurements of high-lying short lived states in {sup 69}As  

Science Conference Proceedings (OSTI)

Lifetimes of high-spin states in {sup 69}As have been measured using Doppler shift attenuation technique with the GASP and RFD setup. The determined transition probabilities indicate large deformation associated with some rotational bands in this nucleus.

Matejska-Minda, M.; Bednarczyk, P.; Fornal, B.; Ciemala, M.; Kmiecik, M.; Krzysiek, M.; Maj, A.; Meczynski, W.; Myalski, S.; Styczen, J.; Zieblinski, M.; Angelis, G. de; Huyuk, T.; Michelagnoli, C.; Sahin, E.; Aydin, S.; Farnea, E.; Menegazzo, R.; Recchia, F.; Ur, C. A. [Institute of Nuclear Physics, Polish Academy of Sciences, Krakow (Poland); INFN, Laboratori Nazionali di Legnaro, Legnaro (Italy); Dipartimento di Fisica e INFN Padova (Italy); Dipartimento di Fisica e INFN Milano (Italy); Heavy Ion Laboratory, University of Warsaw (Poland); University of York (United Kingdom); and others

2012-10-20T23:59:59.000Z

138

FISSION YIELDS AND LIFETIMES FOR MUON INDUCED FISSION IN 235U AND 238U  

E-Print Network (OSTI)

University of California. FISSION YIELDS AL\\JD LIFETIMES FORfor his assistance in the fission chamber calibrations andCl8 (1978) 1452. Table 1 Fission yields yf Nucleus 23su 23Su

Ahmad, S.

2012-01-01T23:59:59.000Z

139

Theory of SEI Formation in Rechargeable Batteries: Capacity Fade, Accelerated Aging and Lifetime Prediction  

E-Print Network (OSTI)

Cycle life is critically important in applications of rechargeable batteries, but lifetime prediction is mostly based on empirical trends, rather than mathematical models. In practical lithium-ion batteries, capacity fade ...

Pinson, Matthew Bede

140

The Needs of a Lifetime: The Search for Security, 1865-1914  

E-Print Network (OSTI)

age in an era without Social Security. v Table of Contentsthem for mortgages or securities, or to secure various formsLifetime: The Search for Security, 1865-1914 A Dissertation

Yang, Tony

2009-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "incremental lifetime cancer" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


141

Lifetime reliability assessment with aging information from low-level sensors  

Science Conference Proceedings (OSTI)

Aggressive technology scaling has led Integrated Circuits (ICs) suffer from ever-increasing wearout effects. As a consequence, Dynamic Reliability Management (DRM) becomes an essential approach to assure IC's lifetime reliability. Accurate and efficient ... Keywords: dynamic reliability management, nbti, reliability

Yao Wang; Sorin D. Cotofana; Liang Fang

2013-05-01T23:59:59.000Z

142

Cascade Problems in Some Atomic Lifetime Measurements at a Heavy-Ion Storage Ring  

SciTech Connect

Lifetimes of 3s{sup 2}3p{sup k} ground configuration levels of Al-, Si-, P-, and S-like ions of Be, Co, and Ni have been measured at a heavy-ion storage ring. Some of the observed decay curves show strong evidence of cascade repopulation from specific 3d levels that feature lifetimes in the same multi-millisecond range as the levels of the ground configuration.

Tr?bert, E; Hoffmann, J; Krantz, C; Wolf, A; Ishikawa, Y; Santana, J

2008-10-09T23:59:59.000Z

143

Ratio of D/sup 0/ and D/sup +/ lifetimes from their semileptonic decays  

Science Conference Proceedings (OSTI)

The conventional expectation for the decays of D mesons assumes that the charm quark decays in the presence of light, spectator quarks and thus the lifetimes of both charged and uncharged states are equal. In this article, evidence is presented from DELCO (at SPEAR) that the D lifetimes are quite different for neutral and charged mesons, and the results which have also become available from other experiments are reviewed.

Donaldson, G.J.

1980-06-01T23:59:59.000Z

144

Lifetime and diffusion length measurements on silicon material and solar cells. [Intentionally doped with impurities  

DOE Green Energy (OSTI)

Experimental methods were evaluated for the determination of lifetime and diffusion length in silicon intentionally doped with potentially lifetime-degrading impurities found in metallurgical grade silicon, impurities which may be residual in low-cost silicon intended for use in terrestrial flat-plat arrays. Results obtained by these methods were compared for mutual consistency. Lifetime measurements were made using a steady-state photoconductivity method, which was compared with a photoconductivity decay technique. Diffusion length determinations were made using short-circuit current measurements under penetrating illumination. This method was compared with a direct measurement of diffusion length using a scanning electron microscope. Mutual consistency among all experimental methods was verified, but steady-state photoconductivity was found preferable to photoconductivity decay at short lifetimes and in the presence of traps. The effects of a number of impurities on lifetime in bulk material, and on diffusion length in cells fabricated from this material, were determined. Results were compared with those obtained by others on the same material and devices using different techniques. General agreement was found in terms of the hierarchy of impurities which degrade the lifetime.

Othmer, S.; Chen, S.C.

1977-01-01T23:59:59.000Z

145

Simulation free measurement of the B+ lifetime using decays selected using displaced tracks  

SciTech Connect

The lifetime of the B{sup {+-}} meson is measured using the decay channel B{sup +} {yields} {bar D}{sup 0}{pi}{sup +}. The measurement is made using approximately 1.0 fb{sup -1} of Tevatron proton-anti-proton collision data at {radical}s = 1.96 TeV collected by the CDF detector. The data were collected using impact parameter based triggers that were designed to select events with a secondary vertex. The trigger selection criteria result in data rich in a variety of B hadron decays, but intrinsically bias the lifetime distribution of the collected signal events. The traditional way to compensate for the bias is to use information from simulation. Presented here is a new method for correction of the lifetime bias using an analytical technique that uses information from the data only. This eliminates measurement uncertainty due to data and simulation agreement, ultimately resulting in a smaller systematic measurement uncertainty. The B{sup {+-}} lifetime measurement is the first measurement using this new technique and demonstrates its potential for use in future measurements. The B{sup {+-}} lifetime is measured to be {tau}(B{sup {+-}}) = 1.662 {+-} 0.023(stat) {+-} 0.015(syst)ps.

Malde, Sneha; /Oxford U.

2009-03-01T23:59:59.000Z

146

Vibrational Infrared Lifetime of the Anesthetic nitrous oxide gas in solution  

E-Print Network (OSTI)

The lifetime of the asymmetric fundamental stretching 2218 cm$^{-1}$ vibration of the anesthetic gas nitrous oxide (N$_2$O) dissolved in octanol and olive oil is reported. These solvents are model systems commonly used to assess anesthetic potency. Picosecond time-scale molecular dynamics simulations have suggested that protein dynamics or membrane dynamics play a role in the molecular mechanism of anesthetic action. Ultrafast infrared spectroscopy with 100 fs time resolution is an ideal tool to probe dynamics of anesthetic molecules on such timescales. Pump-probe studies at the peak of the vibrational band yield a lifetime of $55 \\pm 1$ ps in olive oil and $52 \\pm 1 ps$ in octanol. The similarity of lifetimes suggests that energy relaxation of the anesthetic is determined primarily by the hydrophobic nature of the environment, consistent with models of anesthetic action. The results show that nitrous oxide is a good model system for probing anesthetic-solvent interactions using nonlinear infrared spectroscop...

Chieffo, Logan; Shattuck, Jeffrey; Hong, Mi K; Ziegler, Lawrence; Erramilli, Shyamsunder

2006-01-01T23:59:59.000Z

147

Measuring Lifetimes of Long-Lived Charged Massive Particles Stopped in LHC Detectors  

Science Conference Proceedings (OSTI)

Long-lived charged massive particles (CHAMPs) appear in various particle physics models beyond the standard model. In this Letter, we discuss the prospects for studying the stopping and decaying events of such long-lived CHAMPs at the LHC detectors, and show that the lifetime measurement (and the study of decay products) is possible with the LHC detectors for a wide range of the lifetime O(0.1)-O(10{sup 10}) sec, by using periods of no pp collision. Even a short lifetime of order 1 sec can be measured by (i) identifying the stopping event with the on-line event filter, (ii) immediately making a beam-dump signal which stops the pp collision of the LHC, and at the same time (iii) changing the trigger menu to optimize it for the detection of a CHAMP decay in the calorimeter. Other possibilities are also discussed.

Asai, Shoji; Shirai, Satoshi [Department of Physics, University of Tokyo, Tokyo 113-0033 (Japan); Hamaguchi, Koichi [Department of Physics, University of Tokyo, Tokyo 113-0033 (Japan); Institute for the Physics and Mathematics of the Universe, University of Tokyo, Chiba 277-8568 (Japan)

2009-10-02T23:59:59.000Z

148

Use of Incremental Pricing in Coal Supply and Transportation Agreements to Achieve Power Sales: Report Series of Fuel and Power Market Integration  

Science Conference Proceedings (OSTI)

Increased power market competition is transforming into increased fuel supply competition. This report examines the role that "incremental pricing" for coal supply and transportation services plays in permitting power generators to achieve greater power sales. Surprisingly, the outlook for using such mechanisms for this purpose is more restricted than one might expect.

1997-11-26T23:59:59.000Z

149

Long-run incremental costs and the pricing of electricity. Part II. [Comparative evaluation of marginal cost pricing and average cost pricing  

SciTech Connect

Total costs have essentially the same cost components whether long-run average costs or long-run incremental costs are used. The variable components, chiefly fuel, may be somewhat different in the new incremental plant compared to the old average plant; where the difference is between nuclear fuel and fossil fuel, its size is substantial. However, given the same kind of plant, the current prices of materials and labor will be essentially the same whether used in the new or the old plant with long-run incremental costs (LRIC) or long-run average costs (LRAC). The lower cost of electricity produced in nuclear plants constructed today, as compared to fossil fuel plants constructed at the same time, is not to be confused with the relation between LRIC and LRAC. LRAC is the average cost of electricity from all existing plants priced at their historical costs, which were generally lower than current costs. These average historical costs per kilowatt are still likely to be lower than the current incremental cost per kilowatt of the newest nuclear plant built at present price levels. LRAC is, therefore, still likely to be lower than LRIC for either fossil or nuclear. Data from the Wisconsin Power and Light Company, the Madison Gas and Electric Company, and Tuscon Gas and Electric Company are examined to study some comparisons. Some pricing principles that vary seasonally for resort hotels are reviewed. (MCW)

Morton, W.A.

1976-03-25T23:59:59.000Z

150

The Effective Lifetime of ACSR Full Tension Splice Connector Operated at Higher Temperature  

Science Conference Proceedings (OSTI)

This paper is to address the issues related to integrity of ACSR full tension splice connectors operated at high temperatures. A protocol of integrating analytical and experimental approaches to evaluate the integrity of a full tension single-stage splice connector (SSC) assembly during service at high operating temperature was developed. Based on the developed protocol the effective lifetime evaluation was demonstrated with ACSR Drake conductor SSC systems. The investigation indicates that thermal cycling temperature and frequency, conductor cable tension loading, and the compressive residual stress field within a SSC system have significant impact on the SSC integrity and the associated effective lifetime.

Wang, Jy-An John [ORNL; Lara-Curzio, Edgar [ORNL; King Jr, Thomas J [ORNL; Graziano, Joe [Tennessee Valley Authority (TVA); Chan, John [Electric Power Research Institute (EPRI); Goodwin, Tip [PBS& J

2009-01-01T23:59:59.000Z

151

Nuclear matrix elements from direct lifetime or cross-section measurements  

SciTech Connect

The method of simultaneous lifetime and g factor measurements using a plunger device and the RDDS and TDRIV techniques is introduced. Results on lifetimes and hyperfine-interaction parameters for 2{sup +}{sub 1} states in {sup 104-108}Pd, {sup 96,98,104}Ru, and {sup 92,94}Zr, using a plunger device. Another method to obtain electromagnetic matrix elements is direct cross section measurements using NRF. The method is outlined, and some recent results on {sup 76}Se are shown.

Werner, V.; Cooper, N.; Hinton, M.; Ilie, G.; Radeck, D. [Wright Nuclear Structure Laboratory, Yale University, P.O. Box 208120, New Haven, CT 06520-8120 (United States); Wright Nuclear Structure Laboratory, Yale University, P.O. Box 208120, New Haven, CT 06520-8120 (United States) and Department of Physics, University of Surrey, Guilford, GU27XH (United Kingdom); Wright Nuclear Structure Laboratory, Yale University, P.O. Box 208120, New Haven, CT 06520-8120 (United States) and National Institute for Physics and Nuclear Engineering, P.O. Box MG-6, Bucharest-Magurele (Romania); Wright Nuclear Structure Laboratory, Yale University, P.O. Box 208120, New Haven, CT 06520-8120 (United States) and Institut fuer Kernphysik, Universitaet zu Koeln, Zuelpicher Str. 77, 50937 Koeln (Germany)

2012-11-20T23:59:59.000Z

152

Seismic Performance Evaluation of the Jacket Type Offshore Platforms through Incremental Dynamic Analysis considering Soil-Pile-Structure Interaction  

Science Conference Proceedings (OSTI)

Of great interest in Performance-Based Earthquake Engineering (PBEE) is the accurate estimation of the seismic performance of structures. A performance prediction and evaluation procedure is based on nonlinear dynamics and reliability theory. In this method, a full integration over the three key stochastic models is as follow: ground motion hazard curve, nonlinear dynamic displacement demand, and displacement capacity. Further, both epistemic and aleatory uncertainties are evaluated and carried through the analysis.In this paper, jacket and soil-pile system have been modeled using Finite Element program (OpenSees) and the incremental dynamic analysis (IDA) are performed to investigate nonlinear behavior of offshore platforms. The system demand is determined by performing time history response analyses of the jacket under a suite of FEMA/SAC uniform hazard ground motions. The system capacity in terms of the drift ratio against incipient collapse is generally difficult to predict since the structural response goes into nonlinear range before collapse. All the analyses are performed in two directions and the results are compared with each others. The confidence level of a jacket in each direction for a given hazard level is calculated using the procedure described.

Asgarian, Behrouz [K.N. Toosi University of Technology Tehran Iran (Iran, Islamic Republic of); Shokrgozar, Hamed R.; Talarposhti, Ali Shakeri [K.N. Toosi University of Technology, Tehran (Iran, Islamic Republic of)

2008-07-08T23:59:59.000Z

153

THE LIFETIME OF AEROSOL DROPLETS IN AMBIENT AIR: CONSIDERATION OF THE EFFECTS OF SURFACTANTS AND CHEMICAL REACTIONS  

E-Print Network (OSTI)

of various urban sulfate aerosol production mechanisms.radius of an evaporating aerosol droplet in which oxidationEnvironment THE LIFETIME OF AEROSOL DROPLETS IN AMBIENT AIR:

Toossi, R.

2013-01-01T23:59:59.000Z

154

Efficient Battery Management for Sensor Lifetime Malka N. Halgamuge, Student Member, IEEE  

E-Print Network (OSTI)

Efficient Battery Management for Sensor Lifetime Malka N. Halgamuge, Student Member, IEEE It is challenging to design a sensor network if sensors are battery powered. Efficient scheduling and budgeting battery power in sensor networks has become a critical issue in net- work design. We investigate how

Halgamuge, Malka N.

155

Internal Resistance Identification in Vehicle Power Lithium-Ion Battery and Application in Lifetime Evaluation  

Science Conference Proceedings (OSTI)

According to the characteristic analysis of lithium-ion power battery, battery accelerate life test is carried out to obtain the relevant conclusions such as the changing trend of battery ohmic resistance in different conditions. Battery ohmic resistance ... Keywords: Lithium-ion battery, Internal resistance, Equivalent model, Lifetime evaluation

Xuezhe Wei; Bing Zhu; Wei Xu

2009-04-01T23:59:59.000Z

156

Photoconductive Decay Lifetime and Suns-Voc Diagnostics of Efficient Heterojunction Solar Cells: Preprint  

DOE Green Energy (OSTI)

We report results of minority carrier lifetime measurements for double-sided p-type Si heterojunction devices and compare Suns-Voc results to Light I-V measurements on 1 cm2 solar cell devices measured on an AM1.5 calibrated XT-10 solar simulator.

Page, M. R.; Iwaniczko, E.; Xu, Y.; Roybal L.; Bauer, R.; Yan, H.-C.; Wang, Q.; Meier, D. L.

2008-05-01T23:59:59.000Z

157

REACTIVITY LIFETIME. TEST RESULTS DL-S-225(T-612118A). Section I, Second Performance  

SciTech Connect

The performance, reliability, stability, and reactivity lifetime variations of the Shippingport PWR are determined under normal steady state conditions. These characteristics are studied over a period of 758 EFPH, at a power level of about 60 Mw(e). Flux-tilt corrections and plant operations during this time are described. (T.F.H.)

1959-03-01T23:59:59.000Z

158

PGCapping: exploiting power gating for power capping and core lifetime balancing in CMPs  

Science Conference Proceedings (OSTI)

Optimizing the performance of a chip multiprocessor (CMP) within a power cap has recently received a lot of attention. However, most existing solutions rely solely on DVFS, which is anticipated to have only limited actuation ranges in the future. Power ... Keywords: chip multiprocessor, control theory, lifetime balancing, power capping, power control, power gating

Kai Ma; Xiaorui Wang

2012-09-01T23:59:59.000Z

159

A new extended Birnbaum-Saunders regression model for lifetime modeling  

Science Conference Proceedings (OSTI)

A new class of extended Birnbaum-Saunders regression models is introduced. It can be applied to censored data and be used more effectively in survival analysis and fatigue life studies. Maximum likelihood estimation of the model parameters with censored ... Keywords: Birnbaum-Saunders distribution, Censored data, Fatigue life distribution, Lifetime data, Local influence analysis

Artur J. Lemonte

2013-08-01T23:59:59.000Z

160

Radiative lifetime of the $a\\ ^3\\Sigma^+$ state of HeH$^+$ from ab initio calculations  

E-Print Network (OSTI)

The first metastable triplet state of HeH$^+$ was found to be present in ion beam experiments, with its lifetime estimated to be between hundreds of milliseconds and thousand of seconds. In this work, we use {\\it ab initio} methods to evaluate the radiative lifetimes of the six vibrational levels of the $a\\ ^3\\Sigma^+$ of HeH$^+$. The transition $a\\ ^3\\Sigma^+ \\rightarrow X \\ ^1\\Sigma^+$ is spin-forbidden, but acquires intensity through spin-orbit interaction with the singlet and triplet $\\Pi$ states. Large scale CASSCF/MRCI calculations using an adapted basis set were performed to determine the potential energy curves of the relevant states of HeH$^+$ as well as the matrix elements of the dipole and spin-orbit operators. The wave functions and energies of the vibrational levels of the $a\\ ^3\\Sigma^+$ and $X \\ ^1\\Sigma^+$ states are obtained using a B-spline method and compared to previous works. We find that radiative lifetime of the vibrational levels increases strongly with $v$, the lifetime of the $v=0$ s...

Loreau, J; Vaeck, N

2010-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "incremental lifetime cancer" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


161

Enhancement of photoluminescence lifetime of ZnO nanorods making use of thiourea  

Science Conference Proceedings (OSTI)

We have investigated correlation of photoluminescence lifetime between zinc oxide (ZnO) nanorods and thiourea-doped ZnO nanorods (tu: CH4N2S). Aqueous solutions of ZnO nanorods were deposited on glass substrate by using pneumatic ...

Erdal Sönmez; Kadem Meral

2012-01-01T23:59:59.000Z

162

Coverage-Based Information Retrieval for Lifetime Maximization in Sensor Networks  

E-Print Network (OSTI)

Coverage-Based Information Retrieval for Lifetime Maximization in Sensor Networks Tong Zhao {ttzhao, qzhao}@ece.ucdavis.edu Abstract--We consider information retrieval in a wireless sensor network-of-service (QoS) specific information retrieval for the reconstruction of a spatially correlated random signal

Islam, M. Saif

163

ATA: adaptive transmission algorithms for prolonging lifetime in underwater sensor networks  

Science Conference Proceedings (OSTI)

The severe energy constraints of sensors and the unique characteristics of underwater sensor networks (UWSNs) present major challenges for the long-term monitoring applications. This paper proposes two novel adaptive transmission algorithms for UWSNs ... Keywords: algorithms, lifetime, underwater sensor networks

Zhongwen Guo; Jinfeng Dou; Wei Han; Guangxu Zhang; Zhengang Ha

2008-05-01T23:59:59.000Z

164

Alternative Size and Lifetime Measurements for High-Energy Heavy-Ion Collisions  

E-Print Network (OSTI)

Two-Particle correlations based on the interference of identical particles has provided the chief means for determining the shape and lifetime of sources in relativistic heavy ion collisions. Here, Strong and Coulomb induced correlations are shown to provide equivalent information.

Scott Pratt; Silvio Petriconi

2003-05-07T23:59:59.000Z

165

Experimental determination of neutron lifetimes through macroscopic neutron noise in the IPEN/MB-01 reactor  

SciTech Connect

The neutron lifetimes of the core, reflector, and global were experimentally obtained through macroscopic neutron noise in the IPEN/MB-01 reactor for five levels of subcriticality. The theoretical Auto Power Spectral Densities were derived by point kinetic equations taking the reflector effect into account, and one of the approaches consider an additional group of delayed neutrons.

Gonnelli, Eduardo; Diniz, Ricardo [Instituto de Pesquisas Energeticas e Nucleares - IPEN/CNEN-SP Travessa R-400, 05508-900, Cidade Universitaria, Sao Paulo (Brazil)

2013-05-06T23:59:59.000Z

166

Energy-aware Gateway Selection for Increasing the Lifetime of Wireless Body Area Sensor Networks  

Science Conference Proceedings (OSTI)

A Wireless Body Area Sensor Network (WBASN) is composed of a set of sensor nodes, placed on, near or within a human body. WBASNs opt to continuously monitor the health conditions of individuals under medical risk, e.g., elders and chronically ill people, ... Keywords: Energy harvesting, Gateway selection algorithm, Network lifetime, Selective engagement of nodes, Wireless Body Area Sensor Networks (WBASN)

Cuneyt Bayilmis; Mohamed Younis

2012-06-01T23:59:59.000Z

167

Network lifetime analytical model for node-disjoint multipath routing in wireless sensor networks  

Science Conference Proceedings (OSTI)

The objective of every sensor node in a sensor network is to send the sensed data in the phenomena to a sink node. The network lifetime is maximal, when the energy consumption of each node is uniform. Many routing protocols select an optimal path to ...

Shiva G. Murthy; R. J. D. Souza; G. Varaprasad

2013-02-01T23:59:59.000Z

168

Development of a high average current polarized electron source with long cathode operational lifetime  

SciTech Connect

Substantially more than half of the electromagnetic nuclear physics experiments conducted at the Continuous Electron Beam Accelerator Facility of the Thomas Jefferson National Accelerator Facility (Jefferson Laboratory) require highly polarized electron beams, often at high average current. Spin-polarized electrons are produced by photoemission from various GaAs-based semiconductor photocathodes, using circularly polarized laser light with photon energy slightly larger than the semiconductor band gap. The photocathodes are prepared by activation of the clean semiconductor surface to negative electron affinity using cesium and oxidation. Historically, in many laboratories worldwide, these photocathodes have had short operational lifetimes at high average current, and have often deteriorated fairly quickly in ultrahigh vacuum even without electron beam delivery. At Jefferson Lab, we have developed a polarized electron source in which the photocathodes degrade exceptionally slowly without electron emission, and in which ion back bombardment is the predominant mechanism limiting the operational lifetime of the cathodes during electron emission. We have reproducibly obtained cathode 1/e dark lifetimes over two years, and 1/e charge density and charge lifetimes during electron beam delivery of over 2?105???C/cm2 and 200 C, respectively. This source is able to support uninterrupted high average current polarized beam delivery to three experimental halls simultaneously for many months at a time. Many of the techniques we report here are directly applicable to the development of GaAs photoemission electron guns to deliver high average current, high brightness unpolarized beams.

C. K. Sinclair; P. A. Adderley; B. M. Dunham; J. C. Hansknecht; P. Hartmann; M. Poelker; J. S. Price; P. M. Rutt; W. J. Schneider; M. Steigerwald

2007-02-01T23:59:59.000Z

169

Prolonging the lifetime of wireless sensor networks using multi-level clustering and heterogeneity  

Science Conference Proceedings (OSTI)

Clustering in wireless sensor networks (WSNs) is an important technique to prolong lifetime of a WSN. This paper proposes energy efficient multi-level clustering scheme called Power Aware Multi-level Clustering (PAMC) for homogeneous wireless sensor ... Keywords: algorithm, energy efficiency, heterogeneity, multi-level clustering, wireless sensor networks

Surender Soni; Vivek Katiyar

2011-02-01T23:59:59.000Z

170

Measurement of the Masses and Lifetimes of B Hadrons at the Tevatron  

SciTech Connect

The latest results for the B Hadron sector at the Tevatron Collider are summarized. The properties of B hadrons can be precisely measured at the Tevatron. In particularly they will focus on the masses and lifetimes. The new Tevatron results for the CP violation in B Hadrons are also discussed.

Catastini, Pierluigi; /Pisa U. /INFN, Pisa

2006-05-01T23:59:59.000Z

171

Energy-optimal SRAM supply voltage scheduling under lifetime and error constraints  

Science Conference Proceedings (OSTI)

This work addresses the energy efficiency of the memory architecture in safety-critical systems that have to guarantee a given level of service and a minimum lifetime. We specifically target SRAM structures in which decreased reliability manifests itself ... Keywords: NBTI, SRAM, aging, energy optimization, reliability

Andrea Calimera, Enrico Macii, Massimo Poncino

2013-05-01T23:59:59.000Z

172

Measurement and model assessment of fluorescence lifetime sensing in multiply scattering media  

E-Print Network (OSTI)

The generation and propagation of fluorescence light within biological tissue offers the potential for biomedical diagnostics and analyte sensing. Arising from an exogenous fluorescent dye injected as a contrast agent or immobilized in a polymer implant, the fluorescent decay kinetics can be sensitive to the tissue??s biochemical environment, providing quantitative in vivo information of the confined tissue site. The impact of light propagation and decay kinetics upon the measured signals is important for consideration, simply because tissue scatters light, giving rise to nanosecond photon time-of-flights that are comparable to fluorescence relaxation kinetics. The goal of this study is to develop a time-dependent model describing (i) the generation of fluorescence from dyes exhibiting multi-exponential or more complex kinetics and (ii) its propagation in scattering media. In the preliminary study, fluorescence lifetime spectroscopy is investigated in tissue-like scattering solution. Two fluorescent dyes, 3,3-diethylthiatricarbocyanine iodide (DTTCI) and Indocynanine Green (ICG), which exhibit distinctly different lifetimes and each exhibits single-exponential decay kinetics, were employed. Measurements of phase-modulation as a function of modulation frequency were made at varying concentration ratios of the two dyes to experimentally simulate fluorescence multi-exponential decay kinetics in non-scattering and scattering solutions. The results suggest that frequency-domain measurements of fluorescent decay kinetics along with models of light propagation may be enhanced by scatter in order to probe kinetics more sensitively than in non-scattering solutions. The next study involved fluorescence lifetime sensing in scattering and non-scattering solutions with a pH sensitive dye, Carboxy Seminaphthofluorescein-1 (C-SNAFL-1), which is known to exhibit multi-exponential decay kinetics. The results demonstrate accurate pH sensing in scattering solution via fluorescence kinetics using a simplified propagation model incorporating an average lifetime. Finally, fluorescence lifetime sensing in immobilized systems were investigated. C-SNAFL-1 was immobilized in poly(ethylene glycol) (PEG) microparticles that were immersed in buffered polystyrene solutions. The results demonstrate the ability to perform pH sensing with fluorescence lifetime without the confounding effect of fluorophore loading or the use of 'reference' measurement within multiply scattering systems. In addition, the stability of the immobilized fluorescence sensor and the reliability of fluorescence lifetime measurement verify the prospect of this technology for implantable purposes.

Kuwana, Eddy

2003-05-01T23:59:59.000Z

173

Wafer Preparation and Iodine-Ethanol Passivation Procedure for Reproducible Minority-Carrier Lifetime Measurement (Poster)  

DOE Green Energy (OSTI)

Measurement of the bulk minority-carrier lifetime (T{sub b}) by optical methods, such as photocurrent decay or quasi-steady-state photoconductance (QSSPC), is strongly influenced by surface recombination. Several techniques are known to lower the effective surface recombination velocity, including the following: use of oxidation, floating N/P junction, SiN:H layer, HF immersion, and use of iodine in ethanol or methanol (I-E solution). Using I-E appears to be very simple and does not require any high-temperature treatment such as oxidation, diffusion, or nitridation processes, which can change T{sub b}. However, this is not a preferred procedure within the photovoltaic community because it is difficult to obtain same T{sub b} values reproducibly, particularly when the wafer lifetime is long. The objectives are: (1) Investigate various reasons why lifetime measurements may be irreproducible using I-E solution passivation. (2) Study the influence of the strength of iodine in the ethanol solution, wafer-cleaning procedures, influence of the wafer container during lifetime measurements, and the stability of I-E. (3) Compare lifetimes of wafers (having different T{sub b}) by various techniques such as QSSPC and transient photoconductive decay using short laser pulses of different light intensity; (4) Make minority-carrier diffusion length (L) measurements by a surface photovoltage technique, and to use T{sub b} and L data to determine diffusivity (D) values for various impurity and defect concentrations, using the relationship L{sup 2} = D* T{sub b}.

Sopori, B.; Rupnowski, P.; Appel, J.; Mehta, V.; Li, C.; Johnston, S.

2008-05-01T23:59:59.000Z

174

A Hybrid Forming System: Electrical-Assisted Double Side Incremental Forming (EADSIF) Process for Enhanced Formability and Geometrical Flexibility  

Science Conference Proceedings (OSTI)

The objectives of this project are to establish the scientific bases, engineering technologies and energy/emission impact of a novel dieless forming process, Double side Incremental Forming (DSIF), and to explore the effectiveness of its hybrid variation, Electrical-Assisted Double Side Incremental Forming (EADSIF), on increasing the formability of metallic sheets. The scope of this project includes: (1) the analysis of environmental performance of the proposed new process as compared to conventional sheet metal forming processes; (2) the experimental investigation of the process capabilities of DSIF and EADSIF via the self-designed and newly established lab-scale EADSIF equipment; (3) the development of the essential software in executing the new proposed process, i.e., the toolpath generation algorithms; and finally (4) the exploration of the electricity effect on material deformation. The major accomplishments, findings and conclusions obtained through this one and a half years exploratory project are: (1) The first industrial medium-size-scale DSIF machine using two hexapods, capable of handling a sheet area up to 675 mm x 675 mm, was successfully completed at Ford. (2) The lab-scale of the DSIF machine was designed, fabricated and assembled to form a workpiece up to 250 mm x 250 mm. (3) Parts with arbitrary freeform double-curvatures using the genetic, not geometric-specific tooling were successfully formed using both machines. (4) The methodology of the life cycle analysis of DSIF was developed and energy consumption was measured and compared to conventional forming processes. It was found that the DSIF process can achieve 40% to 90% saving when the number of parts produced is less than 50. Sensitivity analysis was performed and showed that even at very large number of produced parts (greater than 2000), incremental forming saves at least 5% of the energy used in conventional forming. (5) It was proposed to use the offset between the two universal tools in DSIF to actively create a squeezing effect on sheet metal and therefore, increase the geometric accuracy. The idea was confirmed through both experimental and numerical validations. (6) A novel toolpath strategy, i.e., the so-called In-to-out toolpath or accumulative toolpath, was proposed to further increase formability and geometric accuracy compared to the SPIF configuration. A dimensional form accuracy of 1 mm can be achieved using the new strategy. (7) The effect of electricity on magnesium alloy was experimentally investigated. It was found that the formability has a ridge with respect to the applied current density and pulse duration. This finding implies that there are multiple choices of process parameters that are workable depending on the desired microstructure. The above results demonstrated that DSIF/EADSIF is a promising forming technology that can create impacts in revolutionizing how the prototyping and small volume production of sheet metals will be fabricated, i.e., it can (1) eliminate the need of casting and machining of drawing dies; (2) tailor material utilization to function requirement therefore achieving a light weight product; (3) reduce the amount of sheet metal scraps; and (4) shorten the engineering and manufacturing time for sheet metal parts from the current 8 {approx} 25 weeks to less than 1 week after the technology is fully developed. DSIF/EADSIF can be implemented in aerospace, automotive and appliance industries, or be used for producing personalized and point-of-use products in medical industry. Our analysis has shown that once developed, verified and demonstrated, the implementation and growth of DSIF will increase U.S. manufacturing competitiveness, advance machine tool and software industries, and create opportunities for emerging clean energy and low-carbon economy with estimated energy savings of 11 TBtu and CO2 reduction of 1 million tons per year. The work has been disseminated into three (3) journal articles and two (2) provisional patent submissions. A new company has been spun off from this research group aiming to c

Jian Cao; Z. Cedric Xia; Timothy G. Gutowski; John Roth

2012-04-28T23:59:59.000Z

175

Wafer Preparation and Iodine-Ethanol-Ethanol Passivation Procedure for Reproducible Minority-Carrier Lifetime Measurement: Preprint  

DOE Green Energy (OSTI)

This paper describes reasons that lifetime measurments may be irreproducible using iodine-in-ethanol (I-E) passivation. Possible factors include the strength of the iodine in ethanol solution, wafer cleaning procedures, influence of wafer container during lifetime measurement, and stability of I-E.

Sopori, B.; Rupnowski, P.; Appel, J.; Mehta, V.; Li, C.; Johnston, S.

2008-05-01T23:59:59.000Z

176

Benefits of quantile regression for the analysis of customer lifetime value in a contractual setting: An application in financial services  

Science Conference Proceedings (OSTI)

The move towards a customer-centred approach to marketing, coupled with the increasing availability of customer transaction data, has led to an interest in understanding and estimating customer lifetime value (CLV). Several authors point out that, when ... Keywords: Customer lifetime value, Customer relationship management (CRM), Customer segmentation, Database marketing, Prediction interval, Quantile regression

Dries F. Benoit; Dirk Van den Poel

2009-09-01T23:59:59.000Z

177

Materials Lifetime  

Science Conference Proceedings (OSTI)

Tel: (765) 456-6218. E-mail: pliaw@utk.edu. E-mail: rab1@utk.edu. Fax: (765) 456-6925. Email:dklarstrom@haynesintl.com. Dr. R. P. Wei. Dr. D. G. Harlow.

178

B Lifetime  

NLE Websites -- All DOE Office Websites (Extended Search)

Project Contact: Thomas Jordan - jordant@fnal.gov Web Maintainer: qnet-webmaster@fnal.gov Last Update: April 13, 2001 http:quarknet.fnal.govrun2transverse...

179

B Lifetime  

NLE Websites -- All DOE Office Websites (Extended Search)

the beam pipe (2.5 cm)? References Assignments: Identifying B Project Contact: Thomas Jordan - jordant@fnal.gov Web Maintainer: qnet-webmaster@fnal.gov Last Update: January 10,...

180

Particle Lifetimes  

NLE Websites -- All DOE Office Websites (Extended Search)

Finding the Energy-Momentum Relationship       In classical physics, we can say that if we hold potential energy to be zero, then the total energy of an object...

Note: This page contains sample records for the topic "incremental lifetime cancer" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


181

Spontaneous fission lifetimes from the minimization of self-consistent collective action  

E-Print Network (OSTI)

The spontaneous fission lifetime of 264Fm has been studied within nuclear density functional theory by minimizing the collective action integral for fission in a two-dimensional quadrupole collective space representing elongation and triaxiality. The collective potential and inertia tensor are obtained self-consistently using the Skyrme energy density functional and density-dependent pairing interaction. The resulting spontaneous fission lifetimes are compared with the static result obtained with the minimum-energy pathway. We show that fission pathways strongly depend on assumptions underlying collective inertia. With the non-perturbative mass parameters, the dynamic fission pathway becomes strongly triaxial and it approaches the static fission valley. On the other hand, when the standard perturbative cranking inertia tensor is used, axial symmetry is restored along the path to fission; an effect that is an artifact of the approximation used.

Jhilam Sadhukhan; K. Mazurek; A. Baran; J. Dobaczewski; W. Nazarewicz; J. A. Sheikh

2013-10-08T23:59:59.000Z

182

History-based, online, battery lifetime prediction for embedded and mobile devices  

E-Print Network (OSTI)

This paper presents a novel, history-based, statistical technique for online battery lifetime prediction. The approach first takes a one-time, full cycle, voltage measurement of a constant load, and uses it to transform the partial voltage curve of the current workload into a form with robust predictability. Based on the transformed history curve, we apply a statistical method to make a lifetime prediction. We investigate the performance of the implementation of our approach on a widely used mobile device (HP iPAQ) running Linux, and compare it to two similar battery prediction technologies: ACPI and Smart Battery. We employ twenty-two constant and variable workloads to verify the efficacy of our approach. Our results show that this approach is efficient, accurate, and able to adapt to different systems and batteries easily. 1

Ye Wen; Rich Wolski; Chandra Krintz

2003-01-01T23:59:59.000Z

183

Phosphazene Based Additives for Improvement of Safety and Battery Lifetimes in Lithium-Ion Batteries  

DOE Green Energy (OSTI)

There need to be significant improvements made in lithium-ion battery technology, principally in the areas of safety and useful lifetimes to truly enable widespread adoption of large format batteries for the electrification of the light transportation fleet. In order to effect the transition to lithium ion technology in a timely fashion, one promising next step is through improvements to the electrolyte in the form of novel additives that simultaneously improve safety and useful lifetimes without impairing performance characteristics over wide temperature and cycle duty ranges. Recent efforts in our laboratory have been focused on the development of such additives with all the requisite properties enumerated above. We present the results of the study of novel phosphazene based electrolytes additives.

Mason K Harrup; Kevin L Gering; Harry W Rollins; Sergiy V Sazhin; Michael T Benson; David K Jamison; Christopher J Michelbacher

2011-10-01T23:59:59.000Z

184

Laser spectroscopy of the antiprotonic helium atom – its energy levels and state lifetimes  

E-Print Network (OSTI)

The antiprotonic atom is a three-body exotic system consisting of an antiproton, an electron and a helium nucleus. Its surprising longevity was found and has been studied for more than 10 years. In this work, transition energies and lifetimes of this exotic atom were systematically studied by using the antiproton beam of AD(Antiproton Decelerator) facility at CERN, with an RFQ antiproton decelerator, a narrow-bandwidth laser, Cerenkov counters with fast-response photomultiplier tubes, and cryogenic helium target systems. Thirteen transition energies were determined with precisions of better than 200 ppb by a laser spectroscopy method, together with the elimination of the shift effect caused by collisions with surrounding atoms. Fifteen lifetimes (decay rates) of short-lived states were determined from the time distributions of the antiproton-annihilation signals and the resonance widths of the atomic spectral lines. The relation between the magnitude of the decay rates and the transition multipolarity was inv...

Hidetoshi, Yamaguchi

2003-01-01T23:59:59.000Z

185

Theory of SEI Formation in Rechargeable Batteries: Capacity Fade, Accelerated Aging and Lifetime Prediction  

E-Print Network (OSTI)

Cycle life is critically important in applications of rechargeable batteries, but lifetime prediction is mostly based on empirical trends, rather than mathematical models. In practical lithium-ion batteries, capacity fade occurs over thousands of cycles, limited by slow electrochemical processes, such as the formation of a solid-electrolyte interphase (SEI) in the negative electrode, which compete with reversible lithium intercalation. Focusing on SEI growth as the canonical degradation mechanism, we show that a simple single-particle model can accurately explain experimentally observed capacity fade in commercial cells with graphite anodes, and predict future fade based on limited accelerated aging data for short times and elevated temperatures. The theory is extended to porous electrodes, predicting that SEI growth is essentially homogeneous throughout the electrode, even at high rates. The lifetime distribution for a sample of batteries is found to be consistent with Gaussian statistics, as predicted by th...

Pinson, Matthew B

2012-01-01T23:59:59.000Z

186

Comparison of Accelerated Testing with Modeling to Predict Lifetime of CPV Solder Layers (Presentation)  

DOE Green Energy (OSTI)

Concentrating photovoltaic (CPV) cell assemblies can fail due to thermomechanical fatigue in the die-attach layer. In this presentation, we show the latest results from our computational model of thermomechanical fatigue. The model is used to estimate the relative lifetime of cell assemblies exposed to various temperature histories consistent with service and with accelerated testing. We also present early results from thermal cycling experiments designed to help validate the computational model.

Silverman, T. J.; Bosco, N.; Kurtz, S.

2012-03-01T23:59:59.000Z

187

Lifetime of oil drops pressed by buoyancy against a planar interface: Large drops  

E-Print Network (OSTI)

In a previous report [10] it was shown that emulsion stability simulations are able to reproduce the lifetime of micrometer-size drops of hexadecane pressed by buoyancy against a planar water-hexadecane interface. It was confirmed that small drops (rioil stabilized with bovine serum albumin. The potential obtained is then employed to study the lifetime of deformable drops in the range 10 \\leq ri \\leq 1000 {\\mu}m. It is established that the average lifetime of these drops can be adequately replicated using the model of truncated spheres. However, the results depend sensibly on the expressions of the initial distance of deformation and the maximum film radius used in the calculations. The set of equations adequate for large drops is not satisfactory for medium-size drops (10 \\leq ri \\leq 100 {\\mu}m), and vice versa. In the case of large particles, the increase in the interfacial area as a consequence of the deformation of the drops generates a very large repulsive barrier which opposes coalescence. Nevertheless, the buoyancy force prevails. As a consequence, it is the hydrodynamic tensor of the drops which determine the characteristic behavior of the lifetime as a function of the particle size. While the average values of the coalescence time of the drops can be justified by the mechanism of film thinning, the scattering of the experimental data of large drops cannot be rationalized using the methodology previously described. A possible explanation of this phenomenon required elaborate simulations which combine deformable drops, capillary waves, repulsive interaction forces, and a time-dependent surfactant adsorption.

Clara Rojas; Máximo García-Sucre; Germán Urbina-Villalba

2010-12-15T23:59:59.000Z

188

Quasi-particle Lifetimes in a dx2?y2 Superconductor  

E-Print Network (OSTI)

We consider the lifetime of quasi-particles in a d-wave superconductor due to scattering from antiferromagnetic spin-fluctuations, and explicitly separate the contribution from Umklapp processes which determines the electrical conductivity. Results for the temperature dependence of the total scattering rate and the Umklapp scattering rate are compared with relaxation rates obtained from thermal and microwave conductivity measurements, respectively. Typeset using REVTEX

Daniel Duffy; P. J. Hirschfeld; Douglas J. Scalapino

2008-01-01T23:59:59.000Z

189

Spontaneous fission modes and lifetimes of super-heavy elements in the nuclear density functional theory  

E-Print Network (OSTI)

Lifetimes of super-heavy (SH) nuclei are primarily governed by alpha decay and spontaneous fission (SF). Here we study the competing decay modes of even-even SH isotopes with 108 cold fusion" and "hot fusion" reactions. The region of long-lived SH nuclei is expected to be centered on $^{294}$Ds with a total half-life of ?1.5 days.

A. Staszczak; A. Baran; W. Nazarewicz

2012-08-06T23:59:59.000Z

190

Renewals for exponentially increasing lifetimes, with an application to digital search trees  

E-Print Network (OSTI)

We show that the number of renewals up to time $t$ exhibits distributional fluctuations as $t\\to\\infty$ if the underlying lifetimes increase at an exponential rate in a distributional sense. This provides a probabilistic explanation for the asymptotics of insertion depth in random trees generated by a bit-comparison strategy from uniform input; we also obtain a representation for the resulting family of limit laws along subsequences. Our approach can also be used to obtain rates of convergence.

Dennert, Florian

2007-01-01T23:59:59.000Z

191

Source fabrication and lifetime for Li{sup +} ion beams extracted from alumino-silicate sources  

SciTech Connect

A space-charge-limited beam with current densities (J) exceeding 1 mA/cm{sup 2} have been measured from lithium alumino-silicate ion sources at a temperature of {approx}1275 deg. C. At higher extraction voltages, the source appears to become emission limited with J{>=} 1.5 mA/cm{sup 2}, and J increases weakly with the applied voltage. A 6.35 mm diameter source with an alumino-silicate coating, {<=}0.25 mm thick, has a measured lifetime of {approx}40 h at {approx}1275 deg. C, when pulsed at 0.05 Hz and with pulse length of {approx}6 {mu}s each. At this rate, the source lifetime was independent of the actual beam charge extracted due to the loss of neutral atoms at high temperature. The source lifetime increases with the amount of alumino-silicate coated on the emitting surface, and may also be further extended if the temperature is reduced between pulses.

Roy, Prabir K.; Greenway, Wayne G.; Kwan, Joe W. [Lawrence Berkeley National Laboratory (LBNL), One Cyclotron Road, Berkeley, California 94720 (United States)

2012-04-15T23:59:59.000Z

192

Source fabrication and lifetime for Li+ ion beams extracted from alumino-silicate sources  

Science Conference Proceedings (OSTI)

A space-charge-limited beam with current densities (J) exceeding 1 mA/cm{sup 2} have been measured from lithium alumino-silicate ion sources at a temperature of #24;~1275#14;{degrees} C. At higher extraction voltages, the source appears to become emission limited with J #21;{>=} 1.5 mA/cm{sup 2}, and J increases weakly with the applied voltage. A 6.35 mm diameter source with an alumino-silicate coating, {<=}#20;0.25 mm thick, has a measured lifetime of ~#24;40 hours at ~#24;1275#14;{degrees} C, when pulsed at 0.05 Hz and with pulse length of #24;~6 ?s each. At this rate, the source lifetime was independent of the actual beam charge extracted due to the loss of neutral atoms at high temperature. The source lifetime increases with the amount of alumino-silicate coated on the emitting surface, and may also be further extended if the temperature is reduced between pulses.

Roy, Prabir K.; Greenway, Wayne G.; Kwan, Joe W

2012-03-05T23:59:59.000Z

193

Source fabrication and lifetime for Li+ ion beams extracted from alumino-silicate sources  

SciTech Connect

A space-charge-limited beam with current densities (J) exceeding 1 mA/cm{sup 2} have been measured from lithium alumino-silicate ion sources at a temperature of #24;~1275#14;{degrees} C. At higher extraction voltages, the source appears to become emission limited with J #21;{>=} 1.5 mA/cm{sup 2}, and J increases weakly with the applied voltage. A 6.35 mm diameter source with an alumino-silicate coating, {<=}#20;0.25 mm thick, has a measured lifetime of ~#24;40 hours at ~#24;1275#14;{degrees} C, when pulsed at 0.05 Hz and with pulse length of #24;~6 μs each. At this rate, the source lifetime was independent of the actual beam charge extracted due to the loss of neutral atoms at high temperature. The source lifetime increases with the amount of alumino-silicate coated on the emitting surface, and may also be further extended if the temperature is reduced between pulses.

Roy, Prabir K.; Greenway, Wayne G.; Kwan, Joe W

2012-03-05T23:59:59.000Z

194

Macroparticle simulations of antiproton lifetime at 150 GeV in the te vatron  

SciTech Connect

In this paper we report on a systematic study of antiproton lifetime at the injection energy of 150 GeV in the Tevatron. Our parallel beam-beam model can handle both strong-strong and weak-strong beam-beam collisions with arbitrary beam-beam separation and beam distributions. In this study, we have only used the weak-strong capability due to the fact that the antiproton intensity is much smaller than the proton intensity. We have included all 72 long-range beam-beam collisions with a linear transfer map between adjacent collision points and taken into account linear chromaticity. The effects of antiproton emittance, beam-beam separation, proton intensity, and machine chromaticity have been investigated. Initial results show that the antiproton lifetime as a function of the proton intensity from the simulation is in good agreement with that from the experimental measurements. The antiproton lifetime can be significantly improved by increasing the beam separation and by reducing the antiproton emittance.

Qiang, Ji; Ryne, Robert D.; Sen, Tanaji; Xiao, Meiqin

2003-05-09T23:59:59.000Z

195

Excitation energies, polarizabilities, multipole transition rates, and lifetimes of ions along the francium isoelectronic sequence  

E-Print Network (OSTI)

Relativistic many-body perturbation theory is applied to study properties of ions of the francium isoelectronic sequence. Specifically, energies of the 7s, 7p, 6d, and 5f states of Fr-like ions with nuclear charges Z = 87 - 100 are calculated through third order; reduced matrix elements, oscillator strengths, transition rates, and lifetimes are determined for 7s - 7p, 7p - 6d, and 6d - 5f electric-dipole transitions; and 7s - 6d, 7s - 5f, and 5f_5/2 - 5f_7/2 multipole matrix elements are evaluated to obtain the lifetimes of low-lying excited states. Moreover, for the ions Z = 87 - 92 calculations are also carried out using the relativistic all-order single-double method, in which single and double excitations of Dirac-Fock wave functions are included to all orders in perturbation theory. With the aid of the SD wave functions, we obtain accurate values of energies, transition rates, oscillator strengths, and the lifetimes of these six ions. Ground state scalar polarizabilities in Fr I, Ra II, Ac III, and Th IV...

Safronova, U I; Safronova, M S

2007-01-01T23:59:59.000Z

196

Ensure Long Lifetimes from Electrolytic Capacitors: a Case Study in LED Light Bulbs  

E-Print Network (OSTI)

Abstract: Electrolytic capacitors are notorious for short lifetimes in high-temperature applications such as LED light bulbs. The careful selection of these devices with proper interpretation of their specifications is essential to ensure that they do not compromise the life of the end product. This application note discusses this problem with electrolytic capacitors in LED light bulbs and provides an analysis that shows how it is possible to use electrolytics in such products. A similar version of this article appeared on EDN, April 6, 2013. Hot LEDs and Short-Lived Electrolytic Capacitors Several years ago, I worked on a few designs for LED light bulbs. Very early on, it became clear that the temperatures of components in such light bulbs can get quite high. I personally measured component temperatures as high as +130°C in light bulbs purchased at local retail stores. Now admittedly, these were early LED bulb designs. Manufacturers now understand that, even though these LED bulbs consume substantially lower power than those they would replace, they still must have good thermal engineering. This is the only way to get the lifetime of the electronics to match the lifetime of the LEDs themselves. I found it disturbing that many of these hot designs contained electrolytic capacitors, which are notorious

Mark Fortunato; Senior Principal; Member Technical Staff

2013-01-01T23:59:59.000Z

197

Measurement of D0 lifetime with the BaBar detector  

SciTech Connect

This work is the result of the researchers carried out during a three years Ph.D. period in the BABAR experiment. The first chapter consists in an introduction to the theoretical aspects of the D{sup 0} meson lifetime determination and CP violation parameters, as well as an overview of the CP violation in the B sector, which is the main topic of the experiment. The description of the experimental apparatus follows with particular attention to the Silicon Vertex Tracker detector, the most critical detector for the determination of decay vertices and thus of lifetimes and time dependent CP violation asymmetries. In the fourth chapter the operation and running of the vertex detector is described, as a result from the experience as Operation Manager of the SVT, with particular attention to the safety of the device and the data quality assurance. The last chapter is dedicated to the determination of the D{sup 0} meson lifetime with the BABAR detector, which is the main data analysis carried out by the candidate. The analysis is characterized by the selection of an extremely pure sample of D{sup 0} mesons for which the decay flight length and proper time is reconstructed. The description of the unbinned maximum likelihood fit follows, as well as the discussion of the possible sources of systematic uncertainties. In the appendix is also presented a preliminary study of a possible development regarding the determination of mixing and CP violation parameters for the D{sup 0} meson.

Simi, Gabriele; /Pisa U. /SLAC

2009-12-17T23:59:59.000Z

198

Precision Measurements of Atomic Lifetimes and Hyperfine Energies in Alkali Like Systems  

Science Conference Proceedings (OSTI)

Financial support of this research project has lead to advances in the study of atomic structure through precision measurements of atomic lifetimes, energy splittings, and transitions energies. The interpretation of data from many areas of physics and chemistry requires an accurate understanding of atomic structure. For example, scientists in the fields of astrophysics, geophysics, and plasma fusion depend on transition strengths to determine the relative abundances of elements. Assessing the operation of discharges and atomic resonance line filters also depends on accurate knowledge of transition strengths. Often relative transition strengths are measured precisely, but accurate atomic lifetimes are needed to obtain absolute values. Precision measurements of atomic lifetimes and energy splittings also provide fundamentally important atomic structure information. Lifetimes of allowed transitions depend most strongly on the electronic wave function far from the nucleus. Alternatively, hyperfine splittings give important information about the electronic wave function in the vicinity of the nucleus as well as the structure of the nucleus. Our main focus throughout this project has been the structure of atomic cesium because of its connection to the study of atomic parity nonconservation (PNC). The interpretation of atomic PNC experiments in terms of weak interaction coupling constants requires accurate knowledge of the electronic wave function near the nucleus as well as far from the nucleus. It is possible to address some of these needs theoretically with sophisticated many-electron atomic structure calculations. However, this program has been able to address these needs experimentally with a precision that surpasses current theoretical accuracy. Our measurements also play the important role of providing a means for testing the accuracy of many-electron calculations and guiding further theoretical development, Atomic systems such as cesium, with a single electron outside of a closed shell, provide the simplest open shell systems for detailed comparisons between experiment and theory. This program initially focused on measurements of excited state atomic lifetimes in alkali atomic systems. Our first measurements of atomic lifetimes in cesium surpassed the precision and accuracy of previous measurements and sparked renewed interest in the need for greater precision in lifetime measurements throughout the atomic physics community. After enhancing the capabilities of the laser systems built for these initial measurements, we began a study hyperfine energy splittings in cesium using a thermal atomic beam. The results surpassed previous measurements by more than an order of magnitude and lead to the first observation of the nuclear magnetic octupole moment in cesium demonstrating the inadequacy of the nuclear shell model for predicting high order nuclear moments. The laser system and atomic beam apparatus developed for these endeavors turned out to be perfectly suited for exploring the possibility of making absolute optical frequency measurements of atomic transitions. We initiated collaboration with researchers at NIST so that the desired optical frequencies could be reference with respect to the primary microwave frequency standard (Cs atomic fountain NIST-FI) via a femtosecond laser frequency comb. Our first absolute optical frequency measurement, of the cesium D2 line, surpassed the accuracy of a previous measurement by more than an order of magnitude. An absolute optical frequency measurement of the cesium D1 line, now near completion, also surpasses previous results and places us in a position to be able to report a new value for the fine structure constant which is the fundamental dimensionless constant that underlies all electromagnetic interactions.

Tanner, Carol E.

2005-03-04T23:59:59.000Z

199

Low dose diagnostic radiation exposure and cancer risk in Trp53+/- mice  

NLE Websites -- All DOE Office Websites (Extended Search)

diagnostic radiation exposure and cancer risk in Trp53+/- mice diagnostic radiation exposure and cancer risk in Trp53+/- mice K Taylor, N Phan, ME Cybulski, L Laframboise, DR Boreham Department of Medical Physics and Applied Radiation Sciences, McMaster University, 1280 Main Street West, Hamilton ON L8S 4K1 The cancer risk associated with exposure to low doses of ionizing radiation has traditionally been extrapolated from effects observed at high doses and high dose rates using a linear no threshold model. Based on this approach, it has been postulated that human exposure to medical imaging involving low doses of x-rays and gamma rays increase an individual's risk of developing cancer throughout their lifetime. Conversely, there is evidence that low doses of gamma radiation increase the latency period of cancer depending upon genotype, cancer type, and the magnitude of

200

Quasars Are Not Light-Bulbs: Testing Models of Quasar Lifetimes with the Observed Eddington Ratio Distribution  

E-Print Network (OSTI)

We use the observed distribution of Eddington ratios as a function of supermassive black hole (BH) mass to constrain models of AGN lifetimes and lightcurves. Given the observed AGN luminosity function, a model for AGN lifetimes (time above a given luminosity) translates directly to a predicted Eddington ratio distribution. Models for self-regulated BH growth, in which feedback produces a 'blowout' decay phase after some peak luminosity (shutting down accretion) make specific predictions for the lifetimes distinct from those expected if AGN are simply gas starved (without feedback) and very different from simple phenomenological 'light bulb' models. Present observations of the Eddington ratio distribution, spanning 5 decades in Eddington ratio, 3 in BH mass, and redshifts z=0-1, agree with the predictions of self-regulated models, and rule out 'light-bulb', pure exponential, and gas starvation models at high significance. We compare the Eddington ratio distributions at fixed BH mass and fixed luminosity (both are consistent, but the latter are much less constraining). We present empirical fits to the lifetime distribution and show how the Eddington ratio distributions place tight limits on AGN lifetimes at various luminosities. We use this to constrain the shape of the typical AGN lightcurve, and provide simple analytic fits. Given independent constraints on episodic lifetimes, most local BHs must have gained their mass in no more than a couple of bright episodes, in agreement with merger-driven fueling models.

Philip F. Hopkins; Lars Hernquist

2008-09-22T23:59:59.000Z

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201

Lifetime Response of a Hi-Nicalon Fiber-Reinforced Melt-Infiltrated SiC Matrix Composites  

DOE Green Energy (OSTI)

Lifetime studies in four-point flexure were performed on a Hi-NicalonTM fiber-reinforced SiC matrix composite over a temperature range of 700 degrees to 1150 degrees C in air. The composite consisted of ~40 vol. % Hi-NicalonTM fiber (8-harness weave) with a 0.5 Mu-m BN fiber coating and a melt-infiltration SiC matrix wand was tested with as-machined surfaces. Lifetime results indicated that the composite exhibited a stress-dependent lifetime at stress levels above an apparent fatigue limit, similar to the trend observed in CG-NicalonTM fiber reinforced CVI SiC matrix composites. At less than or equal to 950 degrees C, the lifetimes of Hi-Nicalon/MI SiC composites decreased with increasing applied stress level and test temperature. However, the lifetimes were extended as test temperature increased from 950 degees to 1150 degrees C as a result of surface crack sealing due to glass formation by the oxidation of Mi SiC matrix. The lifetime governing processes were, in general, attributed to the progressive oxidation of BN fiber coating and formation of glassy phase, which formed a strong bond between fiber and matrix, resulting in embrittlement of the composite with time.

Becher, P.F.; Lin, H.T.; Singh, M.

1999-04-25T23:59:59.000Z

202

Use of silicide fuel in the Ford Nuclear Reactor - to lengthen fuel element lifetimes  

SciTech Connect

Based on economic considerations, it has been proposed to increase the lifetime of LEU fuel elements in the Ford Nuclear Reactor by raising the {sup 235}U plate loading from 9.3 grams in aluminide (UAl{sub x}) fuel to 12.5 grams in silicide (U{sub 3}Si{sub 2}) fuel. For a representative core configuration, preliminary neutronic depletion and steady state thermal hydraulic calculations have been performed to investigate core characteristics during the transition from an all-aluminide to an all-silicide core. This paper discusses motivations for this fuel element upgrade, results from the calculations, and conclusions.

Bretscher, M.M.; Snelgrove, J.L. [Argonne National Lab., IL (United States); Burn, R.R.; Lee, J.C. [Univ. of Michigan, Ann Arbor, MI (United States). Phoenix Memorial Lab.

1995-12-31T23:59:59.000Z

203

Lifetimes of electronic excitations in unoccupied surface states and the image potential states on Pd(110)  

SciTech Connect

The contribution of inelastic electron-electron scattering to the decay rate of excitations in the surface states and first two image potential states at the Y-bar point on the surface is calculated in the GW approximation, and the quasi-momentum dependence of the corresponding contribution for the surface states is analyzed. The mechanisms of electron scattering in these states are studied, and the temperature dependence of the excitation lifetime is analyzed with allowance for the contribution of the electron-phonon interaction calculated earlier.

Tsirkin, S. S., E-mail: tsirkinss@gmail.com; Eremeev, S. V. [Tomsk State University (Russian Federation); Chulkov, E. V. [San Sebastian/Donostia, Donostia International Physics Center (DIPC) (Spain)

2012-10-15T23:59:59.000Z

204

Photo-degradation of Lexan polycarbonate studied using positron lifetime spectroscopy  

SciTech Connect

The free volume properties of pristine and UV irradiated Lexan polycarbonate have been investigated using Positron Lifetime Spectroscopy (PLS). The decrease in o-Ps life time and free volume size of irradiated sample is attributed to free volume modification and formation of more stable free radicals. These free radicals are formed due to the breakage of C-O bonds in Lexan polycarbonate after irradiation. This is also supported by the decrease in the intensity of C-O bond after exposure to UV-radiation as studied from Fourier Transform Infrared (FTIR) spectroscopy and it also shows that benzene ring does not undergo any changes after irradiation.

Hareesh, K.; Sanjeev, Ganesh [Microtron Centre, Department of Physics, Mangalore University, Mangalagangotri-574199 (India); Pandey, A. K. [Radiochemistry Division, Bhabha Atomic Research Centre, Trombay, Mumbai-400085 (India); Meghala, D.; Ranganathaiah, C. [Department of Studies in Physics, University of Mysore, Manasagangotri-570006 (India)

2013-02-05T23:59:59.000Z

205

Measurement of the effective $B^0_s \\rightarrow K^+K^-$ lifetime  

E-Print Network (OSTI)

A measurement of the effective $B^0_s \\rightarrow K^+K^-$ lifetime is presented using approximately $37 pb^{-1}$ of data collected by LHCb during 2010. This quantity can be used to put constraints on contributions from processes beyond the Standard Model in the $B_s$ meson system and is determined by two complementary approaches as $\\tau_{B_s\\to K^+K^-} = 1.440 \\pm 0.096 (stat) \\pm 0.008 (syst) \\pm 0.003 (model) ps$.

Aaij, R; Adeva, B; Adinolfi, M; Adrover, C; Affolder, A; Ajaltouni, Z; Albrecht, J; Alessio, F; Alexander, M; Alkhazov, G; Alvarez Cartelle, P; Alves, A A; Amato, S; Amhis, Y; Anderson, J; Appleby, R B; Aquines Gutierrez, O; Archilli, F; Arrabito, L; Artamonov, A; Artuso, M; Aslanides, E; Auriemma, G; Bachmann, S; Back, J J; Bailey, D S; Balagura, V; Baldini, W; Barlow, R J; Barschel, C; Barsuk, S; Barter, W; Bates, A; Bauer, C; Bauer, Th; Bay, A; Bediaga, I; Belogurov, S; Belous, K; Belyaev, I; Ben-Haim, E; Benayoun, M; Bencivenni, G; Benson, S; Benton, J; Bernet, R; Bettler, M-O; van Beuzekom, M; Bien, A; Bifani, S; Bizzeti, A; Bjørnstad, P M; Blake, T; Blanc, F; Blanks, C; Blouw, J; Blusk, S; Bobrov, A; Bocci, V; Bondar, A; Bondar, N; Bonivento, W; Borghi, S; Borgia, A; Bowcock, T J V; Bozzi, C; Brambach, T; van den Brand, J; Bressieux, J; Brett, D; Brisbane, S; Britsch, M; Britton, T; Brook, N H; Brown, H; Büchler-Germann, A; Burducea, I; Bursche, A; Buytaert, J; Cadeddu, S; Caicedo Carvajal, J M; Callot, O; Calvi, M; Calvo Gomez, M; Camboni, A; Campana, P; Carbone, A; Carboni, G; Cardinale, R; Cardini, A; Carson, L; Carvalho Akiba, K; Casse, G; Cattaneo, M; Charles, M; Charpentier, Ph; Chiapolini, N; Ciba, K; Cid Vidal, X; Ciezarek, G; Clarke, P E L; Clemencic, M; Cliff, H V; Closier, J; Coca, C; Coco, V; Cogan, J; Collins, P; Comerma-Montells, A; Constantin, F; Conti, G; Contu, A; Cook, A; Coombes, M; Corti, G; Cowan, G A; Currie, R; D'Almagne, B; D'Ambrosio, C; David, P; De Bonis, I; De Capua, S; De Cian, M; De Lorenzi, F; De Miranda, J M; De Paula, L; De Simone, P; Decamp, D; Deckenhoff, M; Degaudenzi, H; Deissenroth, M; Del Buono, L; Deplano, C; Derkach, D; Deschamps, O; Dettori, F; Dickens, J; Dijkstra, H; Diniz Batista, P; Domingo Bonal, F; Donleavy, S; Dordei, F; Dosil Suárez, A; Dossett, D; Dovbnya, A; Dupertuis, F; Dzhelyadin, R; Dziurda, A; Easo, S; Egede, U; Egorychev, V; Eidelman, S; van Eijk, D; Eisele, F; Eisenhardt, S; Ekelhof, R; Eklund, L; Elsasser, Ch; d'Enterria, D G; Esperante Pereira, D; Estève, L; Falabella, A; Fanchini, E; Färber, C; Fardell, G; Farinelli, C; Farry, S; Fave, V; Fernandez Albor, V; Ferro-Luzzi, M; Filippov, S; Fitzpatrick, C; Fontana, M; Fontanelli, F; Forty, R; Frank, M; Frei, C; Frosini, M; Furcas, S; Gallas Torreira, A; Galli, D; Gandelman, M; Gandini, P; Gao, Y; Garnier, J-C; Garofoli, J; Garra Tico, J; Garrido, L; Gascon, D; Gaspar, C; Gauvin, N; Gersabeck, M; Gershon, T; Ghez, Ph; Gibson, V; Gligorov, V V; Göbel, C; Golubkov, D; Golutvin, A; Gomes, A; Gordon, H; Grabalosa Gándara, M; Graciani Diaz, R; Granado Cardoso, L A; Graugés, E; Graziani, G; Grecu, A; Greening, E; Gregson, S; Gui, B; Gushchin, E; Guz, Yu; Gys, T; Haefeli, G; Haen, C; Haines, S C; Hampson, T; Hansmann-Menzemer, S; Harji, R; Harnew, N; Harrison, J; Harrison, P F; He, J; Heijne, V; Hennessy, K; Henrard, P; Hernando Morata, J A; van Herwijnen, E; Hicks, E; Holubyev, K; Hopchev, P; Hulsbergen, W; Hunt, P; Huse, T; Huston, R S; Hutchcroft, D; Hynds, D; Iakovenko, V; Ilten, P; Imong, J; Jacobsson, R; Jaeger, A; Jahjah Hussein, M; Jans, E; Jansen, F; Jaton, P; Jean-Marie, B; Jing, F; John, M; Johnson, D; Jones, C R; Jost, B; Kaballo, M; Kandybei, S; Karacson, M; Karbach, T M; Keaveney, J; Kerzel, U; Ketel, T; Keune, A; Khanji, B; Kim, Y M; Knecht, M; Koblitz, S; Koppenburg, P; Kozlinskiy, A; Kravchuk, L; Kreplin, K; Kreps, M; Krocker, G; Krokovny, P; Kruse, F; Kruzelecki, K; Kucharczyk, M; Kumar, R; Kvaratskheliya, T; La Thi, V N; Lacarrere, D; Lafferty, G; Lai, A; Lambert, D; Lambert, R W; Lanciotti, E; Lanfranchi, G; Langenbruch, C; Latham, T; Le Gac, R; van Leerdam, J; Lees, J-P; Lefévre, R; Leflat, A; Lefrançois, J; Leroy, O; Lesiak, T; Li, L; Li Gioi, L; Lieng, M; Liles, M; Lindner, R; Linn, C; Liu, B; Liu, G; Lopes, J H; Lopez Asamar, E; Lopez-March, N; Luisier, J; Machefert, F; Machikhiliyan, I V; Maciuc, F; Maev, O; Magnin, J; Malde, S; Mamunur, R M D; Manca, G; Mancinelli, G; Mangiafave, N; Marconi, U; Märki, R; Marks, J; Martellotti, G; Martens, A; Martin, L; Martin Sánchez, A; Martinez Santos, D; Massafferri, A; Mathe, Z; Matteuzzi, C; Matveev, M; Maurice, E; Maynard, B; Mazurov, A; McGregor, G; McNulty, R; Mclean, C; Meissner, M; Merk, M; Merkel, J; Messi, R; Miglioranzi, S; Milanes, D A; Minard, M-N; Monteil, S; Moran, D; Morawski, P; Mountain, R; Mous, I; Muheim, F; Müller, K; Muresan, R; Muryn, B; Musy, M; Mylroie-Smith, J; Naik, P; Nakada, T; Nandakumar, R; Nardulli, J; Nasteva, I; Nedos, M; Needham, M; Neufeld, N; Nguyen-Mau, C; Nicol, M; Nies, S; Niess, V; Nikitin, N; Nomerotski, A; Novoselov, A; Oblakowska-Mucha, A; Obraztsov, V; Oggero, S; Ogilvy, S; Okhrimenko, O; Oldeman, R; Orlandea, M; Otalora Goicochea, J M; Owen, P; Pal, K; Palacios, J; Palano, A; Palutan, M; Panman, J; Papanestis, A; Pappagallo, M; Parkes, C

2012-01-01T23:59:59.000Z

206

Excitation energies, polarizabilities, multipole transition rates, and lifetimes in Th IV  

E-Print Network (OSTI)

Excitation energies of the ns_{1/2} (n=7-10), np_j (n=7-9), nd_j (n=6-8), nf_{j} (n=5-7), and ng_{j} (n=5-6) states in Th IV are evaluated. First-, second-, third-, and all-order Coulomb energies and first- and second-order Coulomb-Breit energies are calculated. Reduced matrix elements, oscillator strengths, transition rates, and lifetimes are determined for the 96 possible nl_j-n'l'_j' electric-dipole transitions. Multipole matrix elements (7s_{1/2}-6d_j, 7s_{1/2}-5f_j, and 5f_{5/2}-5f_{7/2}) are evaluated to obtain the lifetimes of the $5f_{7/2}$ and 7s_{1/2}$ states. Matrix elements are calculated using both relativistic many-body perturbation theory, complete through third order, and a relativistic all-order method restricted to single and double (SD) excitations. Scalar and tensor polarizabilities for the 5f_{5/2} ground state in Th3+ are calculated using relativistic third-order and all-order methods. These calculations provide a theoretical benchmark for comparison with experiment and theory.

Safronova, U I; Safronova, M S

2006-01-01T23:59:59.000Z

207

Work at FNAL to achieve long electron drift lifetime in liquid argon  

SciTech Connect

This note records some of the work done between July 2005 and July 2006 to achieve long (many milliseconds) electron drift lifetimes in liquid argon at Fermilab. The work is part of a process to develop some experience at Fermilab with the technology required to construct a large liquid argon TPC. This technology has been largely developed by the ICARUS collaboration in Europe and this process can be seen as technology transfer. The capability to produce liquid argon in which electrons have drift lifetimes of several milliseconds is crucial to a successful device. Liquid argon calorimeters have been successfully operated at Fermilab; their electro-negative contaminants are at the level of 10{sup -7} while the TPC we are considering requires a contamination level at the level of 10{sup -11}, tens of parts per trillion (ppt). As well as demonstrating the ability to produce liquid argon at this level of purity, the work is part of a program to test the effect on the electron drift time of candidate materials for the construction of a TPC in liquid argon.

Finley, D.; Jaskierny, W.; Kendziora, C.; Krider, J.; Pordes, S.; Rapidis, P.A.; Tope, T.; /Fermilab

2006-10-01T23:59:59.000Z

208

Constraining cloud lifetime effects of aerosols using A-Train satellite observations  

Science Conference Proceedings (OSTI)

Aerosol indirect effects have remained the largest uncertainty in estimates of the radiative forcing of past and future climate change. Observational constraints on cloud lifetime effects are particularly challenging since it is difficult to separate aerosol effects from meteorological influences. Here we use three global climate models, including a multi-scale aerosol-climate model PNNL-MMF, to show that the dependence of the probability of precipitation on aerosol loading, termed the precipitation frequency susceptibility (S{sub pop}), is a good measure of the liquid water path response to aerosol perturbation ({lambda}), as both Spop and {lambda} strongly depend on the magnitude of autoconversion, a model representation of precipitation formation via collisions among cloud droplets. This provides a method to use satellite observations to constrain cloud lifetime effects in global climate models. S{sub pop} in marine clouds estimated from CloudSat, MODIS and AMSR-E observations is substantially lower than that from global climate models and suggests a liquid water path increase of less than 5% from doubled cloud condensation nuclei concentrations. This implies a substantially smaller impact on shortwave cloud radiative forcing (SWCF) over ocean due to aerosol indirect effects than simulated by current global climate models (a reduction by one-third for one of the conventional aerosol-climate models). Further work is needed to quantify the uncertainties in satellite-derived estimates of S{sub pop} and to examine S{sub pop} in high-resolution models.

Wang, Minghuai; Ghan, Steven J.; Liu, Xiaohong; Ecuyer, Tristan L.; Zhang, Kai; Morrison, H.; Ovchinnikov, Mikhail; Easter, Richard C.; Marchand, Roger; Chand, Duli; Qian, Yun; Penner, Joyce E.

2012-08-15T23:59:59.000Z

209

Application and modeling of frequency-domain lifetime spectroscopy for microsphere-based optical glucose sensors  

E-Print Network (OSTI)

A new glucose affinity sensor based on a homogeneous fluorescence resonance energy transfer (FRET) assay system was developed to monitor the competitive binding between concanavalin A (ConA) and dextran. The FRET quenching kinetics of the donor were analyzed from frequency-domain (FD) measurements as functions of both glucose and acceptor-protein concentrations using a Förster-type decay kinetics model. The results showed that the FD measurements and donor decay kinetics can indicate quantitative changes in the presence of glucose at concentrations ranging from 0 to 224 mg/dL. The second set of experiments proved the feasibility of performing analyte sensing with FD lifetime spectroscopy using microsphere-based sensors in multiple scattering solutions. A well characterized pH-sensitive fluorophore was entrapped in poly(ethylene glycol) microspheres. The particles were then immersed in a buffered polystyrene solution of various pH. Measurements of phase shift and modulation of the generated and multiply scattered fluorescent light were acquired as the modulation frequency of the incident excitation light varied from 10 to 120 MHz. After the measured data were analyzed with the coupled diffusion equations, the obtained lifetimes from the scattering measurements matched values from non-scattering measurements. Lastly, a new two-speed Monte Carlo (MC) simulation was developed to predict light propagation through the sensors and thus was used to evaluate these sensors and to design these sensors for implantation. The model used random packing structure and considered geometric optics and two light propagation speeds. Experimental measurements of phase-shift and modulation of excitation light were made on a cubic phantom with non-fluorescent resin microspheres of 74 µm diameter, and compared to those computed from the MC simulation. The results showed that the mean phase shift (PS) deviation was 0.736° and the mean amplitude deviation was 42%. Quantitative changes in detected fluorescence phase-shift and modulation were investigated for microsphere diameter, volume fraction, refractive index, and fluorophore lifetime. We also found that even though the sensitivity of PS change in the presence of scattering was the same as the value without scattering, the values of PS were magnified due to the scattering effects.

Liang, Feng

2006-12-01T23:59:59.000Z

210

Quasars Are Not Light-Bulbs: Testing Models of Quasar Lifetimes with the Observed Eddington Ratio Distribution  

E-Print Network (OSTI)

We use the observed distribution of Eddington ratios as a function of supermassive black hole (BH) mass to constrain models of AGN lifetimes and lightcurves. Given the observed AGN luminosity function, a model for AGN lifetimes (time above a given luminosity) translates directly to a predicted Eddington ratio distribution. Models for self-regulated BH growth, in which feedback produces a 'blowout' decay phase after some peak luminosity (shutting down accretion) make specific predictions for the lifetimes distinct from those expected if AGN are simply gas starved (without feedback) and very different from simple phenomenological 'light bulb' models. Present observations of the Eddington ratio distribution, spanning 5 decades in Eddington ratio, 3 in BH mass, and redshifts z=0-1, agree with the predictions of self-regulated models, and rule out 'light-bulb', pure exponential, and gas starvation models at high significance. We compare the Eddington ratio distributions at fixed BH mass and fixed luminosity (both ...

Hopkins, Philip F

2008-01-01T23:59:59.000Z

211

Theory and models of material erosion and lifetime during plasma instabilities in a tokamak environment.  

SciTech Connect

Surface and structural damage to plasma-facing components (PFCs) due to the frequent loss of plasma confinement remains a serious problem for the tokamak reactor concept. The deposited plasma energy causes significant surface erosion, possible structural failure, and frequent plasma contamination. Surface damage consists of vaporization, spallation, and liquid splatter of metallic materials. Structural damage includes large temperature increases in structural materials and at the interfaces between surface coatings and structural members. To evaluate the lifetimes of plasma-facing materials and nearby components and to predict the various forms of damage that they experience, comprehensive models (contained in the HEIGHTS computer simulation package) are developed, integrated self-consistently, and enhanced. Splashing mechanisms such as bubble boiling and various liquid magnetohydrodynamic instabilities and brittle destruction mechanisms of nonmelting materials are being examined. The design requirements and implications of plasma-facing and nearby components are discussed, along with recommendations to mitigate and reduce the effects of plasma instabilities on reactor components.

Hassanein, A.; Konkashbaev, I.

1999-11-08T23:59:59.000Z

212

PREDICTION OF DISSOLVER LIFETIMES THROUGH NON-DESTRUCTIVE EVALUATION AND LABORATORY TESTING  

Science Conference Proceedings (OSTI)

Non-destructive evaluation was used as the primary method of monitoring the corrosion degradation of nuclear material dissolvers and assessing the remaining lifetimes. Materials were typically processed in nitric acid based (4-14M) solutions containing fluoride concentrations less than 0.2 M. The primary corrosion issue for the stainless steel dissolvers is the occurrence of localized corrosion near the tank bottom and the heat affected zones of the welds. Laboratory data for a range of operational conditions, including solution chemistry and temperature, was used to assess the impact of processing changes on the dissolver corrosion rate. Experimental and NDE-based general corrosion rates were found to be in reasonable agreement for standard dissolution chemistries consisting of nitric acid with fluorides and at temperatures less than 95 C. Greater differences were observed when chloride was present as an impurity and temperatures exceeded 100 C.

Mickalonis, J.; Woodsmall, T.; Hinz, W.; Edwards, T.

2011-10-03T23:59:59.000Z

213

Lifetime Measurement of the 2{sub 1}{sup +} State in {sup 20}C  

Science Conference Proceedings (OSTI)

Establishing how and when large N/Z values require modified or new theoretical tools is a major quest in nuclear physics. Here we report the first measurement of the lifetime of the 2{sub 1}{sup +} state in the near-dripline nucleus {sup 20}C. The deduced value of {tau}{sub 2{sub 1}{sup +}}=9.8{+-}2.8(stat){sub -1.1}{sup +0.5}(syst) ps gives a reduced transition probability of B(E2;2{sub 1}{sup +}{yields}0{sub g.s.}{sup +})=7.5{sub -1.7}{sup +3.0}(stat){sub -0.4}{sup +1.0}(syst) e{sup 2} fm{sup 4} in good agreement with a shell model calculation using isospin-dependent effective charges.

Petri, M.; Fallon, P.; Macchiavelli, A. O.; Paschalis, S.; Clark, R. M.; Cromaz, M.; Gros, S.; Jeppesen, H. B.; Lee, I. Y. [Nuclear Science Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720 (United States); Starosta, K. [Department of Chemistry, Simon Fraser University, Burnaby, British Columbia, V5A 1S6 (Canada); National Superconducting Cyclotron Laboratory, Michigan State University, East Lansing, Michigan 48824 (United States); Department of Physics and Astronomy, Michigan State University, East Lansing, Michigan 48824 (United States); Baugher, T.; Gade, A.; McDaniel, S.; Miller, D.; Ratkiewicz, A.; Voss, P.; Walsh, K. A. [National Superconducting Cyclotron Laboratory, Michigan State University, East Lansing, Michigan 48824 (United States); Department of Physics and Astronomy, Michigan State University, East Lansing, Michigan 48824 (United States); Bazin, D.; Grinyer, G. F.; Weisshaar, D. [National Superconducting Cyclotron Laboratory, Michigan State University, East Lansing, Michigan 48824 (United States)

2011-09-02T23:59:59.000Z

214

EFFECTIVE LIFETIME ESTIMATE OF CRIMPED POWERLINE SPLICE CONNECTOR OPERATED AT HIGH TEMPERATURE  

SciTech Connect

This paper addresses the thermal-mechanical properties and performance characteristics of full tension splice connectors under high temperature operation, in particular those used in overhead transmission and distribution lines. Due to the increase in power demand existing overhead power transmission lines often need to operate at temperatures higher than those originally considered for their design. This has led to the accelerated aging and degradation of splice connectors. The compressive residual stresses induced by the crimping process within the splice connector provide the clamping forces to secure the conductor and therefore, the determination of the state of compressive residual stresses in splice connectors is a necessary requirement to provide an accurate estimate of their service lifetime. This paper presents a protocol for integrating analytical and experimental approaches to evaluate the integrity of a full tension single-stage splice connector assembly.

Wang, Jy-An John [ORNL; Lara-Curzio, Edgar [ORNL; King Jr, Thomas J [ORNL; An, Ke [ORNL; Hubbard, Camden R [ORNL

2008-01-01T23:59:59.000Z

215

Norwegian National Program for Lifetime Commissioning and Energy Efficient Operation of Buildings  

E-Print Network (OSTI)

The project “Life-Time Commissioning for Energy Efficient Operation of Buildings” is actually a network of industrial companies, private and public entities, and R&D organizations. The overall objective of the project is to contribute to the implementation of life-long commissioning of building HVAC systems, so that this becomes a standardized way of building, operating and maintaining the HVAC systems in Norway. The project is organized as an industry research program with minimum duration of five years. Project members pay an annual membership fee. The main goal for the project is to develop, verify, document and implement suitable tools for functional control of energy and indoor environment in buildings under continuous operation during the entire operational life of the building. This will improve energy efficiency and ensure a rational use of energy and a sound indoor environment. All achievements concerning energy improvement will also contribute to the decrease of CO2 emissions.

Novakovic, V.; Djuric, N.; Holst, J.; Frydenlund, F.

2006-01-01T23:59:59.000Z

216

The implementation of a 3D characteristics solver for the generation of incremental cross sections for reactivity devices in a CANDU reactor  

SciTech Connect

We are presenting issues related to the generation of consistent incremental cross sections for the reactivity devices in a CANDU reactor. Such calculations involve the solution of the neutron transport equation over complex 3D geometries representing a single vertical reactivity device inserted mid-way between two horizontal fuel channels. The DRAGON lattice code has recently been upgraded and can handle the exact geometry of such configurations for trajectory-based transport solvers. Within this framework, the detailed representation of the reactivity devices implies an increase in the number of regions when the strongly absorbing regions and fuel clusters are described without cylinderization. In this paper, a solution based on the characteristics method is compared with the standard procedure, based on the collision probabilities method. The coherence of both solvers is highlighted and a comparison of their computational costs is presented. (authors)

Le Tellier, R.; Hebert, A.; Marleau, G. [Ecole Polytechnique de Montreal, C.P. 6079 suce. Centre-Ville, Montreal, Que. H3C 3A7 (Canada)

2006-07-01T23:59:59.000Z

217

An overview of the United States Department of Energy plant lifetime improvement program  

Science Conference Proceedings (OSTI)

Today, 109 nuclear power plants provide over 20 percent of the electrical energy generated in the US. The operating license of the first of these plants will expire in the year 2000; one third of the operating licenses will expire by 2010 and the remaining plant licenses are scheduled to expire by 2033. The National Energy Strategy assumes that 70 percent of these plants will continue to operate beyond their current license expiration to assist in ensuring an adequate, diverse, and environmentally acceptable energy supply for economic growth. In order to preserve this energy resource in the US three major tasks must be successfully completed: (1) establishment of the regulations, technical standards, and procedures for the preparation and review of a license renewal application; (2) development, verification, and validation of the various technical criteria and bases for needed monitoring, refurbishment, or replacement of plant equipment; and (3) demonstration of the regulatory process. Since 1985, the US Department of Energy (DOE) has been working with the nuclear industry and the US Nuclear Regulatory Commission (NRC) to establish and demonstrate the option to extend the life of nuclear power plants through the renewal of operating licenses. This paper focuses primarily on DOE`s Plant Lifetime Improvement (PLIM) Program efforts to develop the technical criteria and bases for effective aging management and lifetime improvement for continued operation of nuclear power plants. This paper describes current projects to resolve generic technical issues, including degradation of long-lived components, reactor pressure vessel (RPV) embrittlement management approaches, and analytical methodologies to characterize RPV integrity.

Rosinski, S.T.; Clauss, J.M. [Sandia National Labs., Albuquerque, NM (United States); Harrison, D.L. [USDOE, Washington, DC (United States)

1993-08-01T23:59:59.000Z

218

REACTIVITY LIFETIME 5091.4-5806.1 EFPH. CORE I, SEED 1. Test Results T- 612118-B  

SciTech Connect

The Shippingport Atomic Power Station was operated for 715 EFPH from Ang. 11 to Oct. 7, 1959, in order to determine the performance characteristics reliability, stability, and lifetime variation of the core during rated power operation for an extended period of time. The plant was operated at successively lower power levels of 60, 43, and 17 Mwe to extend the Core I, Seed 1 lifetime. Logs and tables are included which present the events and all recorded data in this period. (D.L.C.)

1960-08-01T23:59:59.000Z

219

Evaluation of Lifetime of High Efficiency Organic Photovoltaic Devices: Cooperative Research and Development Final Report, CRADA Number CRD-10-379  

DOE Green Energy (OSTI)

As a part of this joint work, Solarmer and NREL will investigate the lifetime and stability of Organic Photovoltaic Devices based on Solarmer high efficiency active layer materials.

Olson, D.

2013-04-01T23:59:59.000Z

220

Anodic dissolution characteristics and electrochemical migration lifetimes of Sn solder in NaCl and Na2SO4 solutions  

Science Conference Proceedings (OSTI)

In situ water drop tests and anodic polarization tests of pure Sn solder were carried out in deaerated 0.001% NaCl and Na"2SO"4 solutions to determine the correlation between anodic dissolution characteristics and the electrochemical migration lifetime. ... Keywords: Anodic dissolution, Electrochemical migration, Life time, Na2SO4, NaCl, Sn solder

Ja-Young Jung; Shin-Bok Lee; Young-Chang Joo; Ho-Young Lee; Young-Bae Park

2008-07-01T23:59:59.000Z

Note: This page contains sample records for the topic "incremental lifetime cancer" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


221

Algorithm for equalization of cluster lifetimes in a multi-level Beacon enabled 802.15.4 sensor network  

Science Conference Proceedings (OSTI)

We consider the problem of maintaining the prescribed event sensing reliability while maximizing cluster and network lifetime in a multi-cluster 802.15.4 sensor network. Clusters are connected through bridges which also act as cluster coordinators; both ... Keywords: IEEE 802.15.4, Power management, Sensor networks

Jelena Miši?

2007-08-01T23:59:59.000Z

222

Strength and Lifetime Analysis of SMT Solder Joints: An Exemplary Study of the MiniMELF Component  

E-Print Network (OSTI)

-linear three-dimensional finite element (FE) analysis of the thermally loaded struc- ture. In the present case by using the CAD software I-DEAS [2]. To allow for a swift and reliable stress / strain analysis including626 Strength and Lifetime Analysis of SMT Solder Joints: An Exemplary Study of the Mini

Berlin,Technische Universität

223

The Effects of a Hydrogen Environment on the Lifetime of Small-Diameter Drift Chamber Anode Wires  

DOE Green Energy (OSTI)

Possible deterioration of anode sense wires used in a hydrogen-filled neutron detector is investigated. Wires were loaded with free weights and put into a wire detector environment. Stainless Steel, Tungsten, and Platinum wires did not break after exposure to charge equivalent to many wire lifetimes. Furthermore, exposure to hydrogen gas caused no noticeable surface degradation or change in wire yield strength.

King, J; Smith, T; Kunkle, J; Castelaz, J; Thomson, S; Burstein, Z; Bernstein, A; Rosenberg, L; Hefner, M

2005-04-29T23:59:59.000Z

224

Efficient Charging of Supercapacitors for Extended Lifetime of Wireless Sensor Nodes”,in  

E-Print Network (OSTI)

Abstract—This paper describes an efficient charging method for a supercapacitor-operated, solar-powered wireless sensor node called Everlast. Unlike traditional wireless sensors that store energy in batteries, Everlast’s use of supercapacitors enables the system to operate for an estimated lifetime of 20 years without any maintenance. The novelty of this system lies in the feed-forward, pulse frequency modulated converter and open-circuit solar voltage method for maximum power point tracking (MPPT), enabling the solar cell to efficiently charge the supercapacitor and power the node. Experimental results show that by its low-complexity MPPT, Everlast can achieve over 89 % conversion efficiency with lower power overhead than the state-of-the-art by two orders of magnitude, while enabling charging a supercapacitor up to 400 % faster than direct charging. This makes Everlast particularly applicable to miniature-scale, high-impedance energy harvesting systems. Index Terms—Energy harvesting, maximum power point tracking (MPPT), solar power, supercapacitor, wireless sensor node (WSN). I.

Farhan I. Simjee; Pai H. Chou

2008-01-01T23:59:59.000Z

225

Blackbody radiation shift, multipole polarizabilities, oscillator strengths, lifetimes, hyperfine constants, and excitation energies in Ca+  

E-Print Network (OSTI)

A systematic study of Ca+ atomic properties is carried out using high-precision relativistic all-order method where all single, double, and partial triple excitations of the Dirac-Fock wave functions are included to all orders of perturbation theory. Reduced matrix elements, oscillator strengths, transition rates, and lifetimes are determined for the levels up to n = 7. Recommended values and estimates of their uncertainties are provided for a large number of electric-dipole transitions. Electric-dipole scalar polarizabilities for the 5s, 6s, 7s, 8s, 4p, 5p, 3d, and 4d states and tensor polarizabilities for the 4p, 5p, 3d, and 4d states in Ca+ are calculated. Methods are developed to accurately treat the contributions from highly-excited states, resulting in significant (factor of 3) improvement in accuracy of the 3d_{5/2} static polarizability value, 31.8(3) a.u., in comparison with the previous calculation [Arora et al., Phys. Rev. A 76, 064501 (2007)]. The blackbody radiation (BBR) shift of the 4s - 3d_{5/...

Safronova, M S

2010-01-01T23:59:59.000Z

226

Spectroscopy and lifetime measurements of states in {sup 76}Kr populated in {sup 76}Rb decay  

SciTech Connect

The properties of the excited states of {sup 76}Kr, populated in the decay of {sup 76}Rb produced at ISOLDE isotopic separator, have been investigated by using K-conversion electron, {gamma}-ray, and {gamma}-{gamma} coincidence measurements. The lifetimes of several levels have been measured by means of the advanced time-delayed {beta}{gamma}{gamma}(t) method. The identification of 19 new levels and 55 transitions and the information deduced on spin and/or parity of the observed states from K-conversion coefficients, log ft values and decay properties have led to an improved knowledge of the level scheme. In particular, six 1{sup -} states have been definitely identified and J{sup {pi}}=2{sup -} has been assigned to the 2227 keV level, on which a band proposed to have negative-parity and even-spin had been previously observed. The strengths of the E0 and E2 transitions deexciting the 0{sub 2}{sup +} and 0{sub 3}{sup +} states (the latter is here identified with the state at 1598 keV) have been measured. The experimental data concerning the 0{sub 2}{sup +} state have been analyzed in a simple two states mixing model and in the framework of the proton-neutron interacting boson model.

Giannatiempo, A.; Perego, A.; Sona, P.; Nannini, A.; Mach, H.; Fogelberg, B.; Borge, M.J.G.; Tengblad, O.; Fraile, L.M.; Aas, A.J.; Gulda, K. [Dipartimento di Fisica, Universita di Firenze and Istituto Nazionale di Fisica Nucleare, Florence (Italy); Istituto Nazionale di Fisica Nucleare, Florence (Italy); Department of Radiation Sciences, University of Uppsala, S-75121 Uppsala (Sweden); Instituto 'Estructura de la Materia' Consejo Superior de Investigaciones Cientificas, Madrid (Spain); McKinsey and Company, Oslo (Norway); Ministry of Economic Affairs and Labour Department of Innovation, Warsaw (Poland)

2005-10-01T23:59:59.000Z

227

Study of the B-Meson Lifetime and the Performance of the Outer Tracker at LHCb  

E-Print Network (OSTI)

The research in the dissertation addresses two issues: the overall performance of the LHCb Outer Tracker (OT) detectors as shown during quality checks and beam tests; the study of the lifetimes of B+ and B0 mesons at LHCb. Physics at the Large Hadron Collider (LHC) at CERN, Geneva requires high performance detectors. One of the four major LHC experiments is the Large Hadron Collider beauty experiment (LHCb). It is a dedicated B-physics experiment for precision measurements of CP violation in the B-meson system and for studying rare B decays. In order to efficiently reconstruct the trajectories of charged particles, LHCb is equipped with Outer Tracker (OT), consisting of gaseous straw tube detectors. The OT system comprises three stations each consisting of multiple layers of wires in vertical and non-vertical orientation. Basic unit of the stations is the OT module - a self-contained gas-detector unit filled with a counting gas mixture. The outer tracker module production was carefully monitored by variety of...

Vankov, P

2008-01-01T23:59:59.000Z

228

Recovery Act: Low-Cost, Highly Lambertian Reflector Composite For Improved LED Fixture Efficiency and Lifetime  

SciTech Connect

The overall objective of the program was to demonstrate a 98% or greater reflective, highly diffuse, low-cost composite material that significantly improves luminaire efficiency, is able to withstand 50,000 hours or greater luminaire operation under expected LED system thermal and environmental operating extremes and meets the cost targets required to be an effective commercial solution for the Solid State Lighting industry. This project met most of the goals defined and contributed to the understanding of high reflectance, white coatings. Research under this program increased the understanding of coatings development using particle size reduction techniques and preparation of coating solutions with a broad range of particle types. The research explored scale-up of coating systems and generated understanding of processing required for high volume manufacturing applications. The work demonstrated how coating formulation and application technique can translate to material durability and LED system lifetime. The research also demonstrated improvements in lighting efficiency to be gained using high reflectance white coatings.

Teather, Eric

2013-02-15T23:59:59.000Z

229

Comparison of Minority Carrier Lifetime Measurements in Superstrate and Substrate CdTe PV Devices: Preprint  

DOE Green Energy (OSTI)

We discuss typical and alternative procedures to analyze time-resolved photoluminescence (TRPL) measurements of minority carrier lifetime (MCL) with the hope of enhancing our understanding of how this technique may be used to better analyze CdTe photovoltaic (PV) device functionality. Historically, TRPL measurements of the fast recombination rate (t1) have provided insightful correlation with broad device functionality. However, we have more recently found that t1 does not correlate as well with smaller changes in device performance, nor does it correlate well with performance differences observed between superstrate and substrate CdTe PV devices. This study presents TRPL data for both superstrate and substrate CdTe devices where both t1 and the slower TRPL decay (t2) are analyzed. The study shows that changes in performance expected from small changes in device processing may correlate better with t2. Numerical modeling further suggests that, for devices that are expected to have similar drift field in the depletion region, effects of changes in bulk MCL and interface recombination should be more pronounced in t2. Although this technique may provide future guidance to improving CdS/CdTe device performance, it is often difficult to extract statistically precise values for t2, and therefore t2 data may demonstrate significant scatter when correlated with performance parameters.

Gessert, T. A.; Dhere, R. G.; Duenow, J. N.; Kuciauskas, D.; Kanevce, A.; Bergeson, J. D.

2011-07-01T23:59:59.000Z

230

Lifetime Prediction for Degradation of Solar Mirrors using Step-Stress Accelerated Testing (Presentation)  

DOE Green Energy (OSTI)

This research is to illustrate the use of statistical inference techniques in order to quantify the uncertainty surrounding reliability estimates in a step-stress accelerated degradation testing (SSADT) scenario. SSADT can be used when a researcher is faced with a resource-constrained environment, e.g., limits on chamber time or on the number of units to test. We apply the SSADT methodology to a degradation experiment involving concentrated solar power (CSP) mirrors and compare the results to a more traditional multiple accelerated testing paradigm. Specifically, our work includes: (1) designing a durability testing plan for solar mirrors (3M's new improved silvered acrylic "Solar Reflector Film (SFM) 1100") through the ultra-accelerated weathering system (UAWS), (2) defining degradation paths of optical performance based on the SSADT model which is accelerated by high UV-radiant exposure, and (3) developing service lifetime prediction models for solar mirrors using advanced statistical inference. We use the method of least squares to estimate the model parameters and this serves as the basis for the statistical inference in SSADT. Several quantities of interest can be estimated from this procedure, e.g., mean-time-to-failure (MTTF) and warranty time. The methods allow for the estimation of quantities that may be of interest to the domain scientists.

Lee, J.; Elmore, R.; Kennedy, C.; Gray, M.; Jones, W.

2011-09-01T23:59:59.000Z

231

Incremental criticality and yield gradients  

Science Conference Proceedings (OSTI)

Criticality and yield gradients are two crucial diagnostic metrics obtained from Statistical Static Timing Analysis (SSTA). They provide valuable information to guide timing optimization and timing-driven physical synthesis. Existing work in the literature, ...

Jinjun Xiong; Vladimir Zolotov; Chandu Visweswariah

2008-03-01T23:59:59.000Z

232

Blackbody radiation shift, multipole polarizabilities, oscillator strengths, lifetimes, hyperfine constants, and excitation energies in Ca+  

E-Print Network (OSTI)

A systematic study of Ca+ atomic properties is carried out using high-precision relativistic all-order method where all single, double, and partial triple excitations of the Dirac-Fock wave functions are included to all orders of perturbation theory. Reduced matrix elements, oscillator strengths, transition rates, and lifetimes are determined for the levels up to n = 7. Recommended values and estimates of their uncertainties are provided for a large number of electric-dipole transitions. Electric-dipole scalar polarizabilities for the 5s, 6s, 7s, 8s, 4p, 5p, 3d, and 4d states and tensor polarizabilities for the 4p, 5p, 3d, and 4d states in Ca+ are calculated. Methods are developed to accurately treat the contributions from highly-excited states, resulting in significant (factor of 3) improvement in accuracy of the 3d_{5/2} static polarizability value, 31.8(3) a.u., in comparison with the previous calculation [Arora et al., Phys. Rev. A 76, 064501 (2007)]. The blackbody radiation (BBR) shift of the 4s - 3d_{5/2} clock transition in Ca+ is calculated to be 0.381(4) Hz at room temperature, T=300K. Electric-quadrupole 4s -nd and electric-octupole 4s -nf matrix elements are calculated to obtain the ground state multipole E2 and E3 static polarizabilities. The hyperfine constants A are determined for the low-lying levels up to n = 7. The quadratic Stark effect on hyperfine structure levels of 43Ca+ ground state is investigated. These calculations provide recommended values critically evaluated for their accuracy for a number of Ca+ atomic properties for use in planning and analysis of various experiments as well as theoretical modeling.

M. S. Safronova; U. I. Safronova

2010-11-27T23:59:59.000Z

233

Application of the U.S. high cycle fatigue data base to wind turbine blade lifetime predictions  

DOE Green Energy (OSTI)

This paper demonstrates a methodology for predicting the service lifetime of wind turbine blades using the high-cycle fatigue data base for typical U.S. blade materials developed by Mandell, et al. (1995). The first step in the analysis is to normalize the data base (composed primarily of data obtained from specialized, relatively small coupons) with fatigue data from typical industrial laminates to obtain a Goodman Diagram that is suitable for analyzing wind turbine blades. The LIFE2 fatigue analysis code for wind turbines is then used for the fatigue analysis of a typical turbine blade with a known load spectrum. In the analysis, a linear damage model, Miner`s Rule, is used to demonstrate the prediction of the service lifetime for a typical wind turbine blade under assumed operating strain ranges and stress concentration factors. In contrast to typical European data, the asymmetry in this data base predicts failures under typical loads to be compressive.

Sutherland, H.J. [Sandia National Labs., Albuquerque, NM (United States); Mandell, J.F. [Montana State Univ., Bozeman, MT (United States)

1995-12-01T23:59:59.000Z

234

Long lifetime, low intensity light source for use in nighttime viewing of equipment maps and other writings  

DOE Patents (OSTI)

A long-lifetime light source is discussed with sufficiently low intensity to be used for reading a map or other writing at nightime, while not obscuring the user's normal night vision. This light source includes a diode electrically connected in series with a small power source and a lens properly positioned to focus at least a portion of the light produced by the diode.

Frank, A.M.; Edwards, W.R.

1982-03-23T23:59:59.000Z

235

Long lifetime, low intensity light source for use in nighttime viewing of equipment maps and other writings  

DOE Patents (OSTI)

A long-lifetime light source with sufficiently low intensity to be used for reading a map or other writing at nighttime, while not obscuring the user's normal night vision. This light source includes a diode electrically connected in series with a small power source and a lens properly positioned to focus at least a portion of the light produced by the diode.

Frank, Alan M. (Livermore, CA); Edwards, William R. (Modesto, CA)

1983-01-01T23:59:59.000Z

236

Long lifetime, low intensity light source for use in nighttime viewing of equipment maps and other writings  

DOE Patents (OSTI)

A long-lifetime light source with sufficiently low intensity to be used for reading a map or other writing at nighttime, while not obscuring the user's normal night vision is disclosed. This light source includes a diode electrically connected in series with a small power source and a lens properly positioned to focus at least a portion of the light produced by the diode. 1 fig.

Frank, A.M.; Edwards, W.R.

1983-10-11T23:59:59.000Z

237

Performance of ad hoc networks with two-hop relay routing and limited packet lifetime (extended version)  

Science Conference Proceedings (OSTI)

We consider a mobile ad hoc network consisting of three types of nodes (source, destination and relay nodes) and using the two-hop relay routing. This type of routing takes advantage of the mobility and the storage capacity of the nodes, called the relay ... Keywords: Delay tolerant network, Limited packet lifetime, Mobile ad hoc network, Mobility model, Performance analysis, Two-hop relay protocol

Ahmad Al Hanbali; Philippe Nain; Eitan Altman

2008-06-01T23:59:59.000Z

238

171Yb+ System Stability, 5D3/2 Hyperfine State Detection Efficiency and F=2 Lifetime  

E-Print Network (OSTI)

A data acquisition system is described that is designed to stabilize cooling and probe rates to maximize detection sensitivity and minimize possible systematic errors due to correlations between drifting experimental conditions and varying drive parameters. Experimental parameters that affect the Yb171 5D3/2 hyperfine state preparation and detection efficiency are characterized and optimized. A set of wait times for optimal sampling of the D3/2(F=2) lifetime is chosen and used to measure that lifetime with high statistical sensitivity. A systematic variation in this lifetime seems to be apparent. The source of the variation was not identified, but ion number and cooling rate appear to be ruled out. A net determination is made of tau=61.8ms+-(0.6)_stat+-(6.4)_sys which is significantly longer than other measurements of the same quantity. An alternate shelving scheme is proposed that would provide S-D state discrimination for Yb even isotopes as well as improved sensitivity for D state hyperfine discrimination ...

Schacht, M

2013-01-01T23:59:59.000Z

239

Spontaneous Fission Modes and Lifetimes of Superheavy Elements in the Nuclear Density Functional Theory  

Science Conference Proceedings (OSTI)

Background: The reactions with the neutron-rich 48Ca beam and actinide targets resulted in the detection of new superheavy (SH) nuclides with Z=104 118. The unambiguous identification of the new isotopes, however, still poses a problem because their -decay chains terminate by spontaneous fission (SF) before reaching the known region of the nuclear chart. The understanding of the competition between -decay and SF channels in SH nuclei is, therefore, of crucial importance for our ability to map the SH region and to assess its extent. Purpose: We perform self-consistent calculations of the competing decay modes of even-even SH isotopes with 108 Z 126 and 148 N 188. Methods: We use the state-of-the-art computational framework based on self-consistent symmetry-unrestricted nuclear density functional theory capable of describing the competition between nuclear attraction and electrostatic repulsion. We apply the SkM* Skyrme energy density functional. The collective mass tensor of the fissioning superfluid nucleus is computed by means of the cranking approximation to the adiabatic time-dependent Hartree-Fock-Bogoliubov (HFB) approach. This paper constitutes a systematic self-consistent study of spontaneous fission in the SH region, carried out at a full HFB level, that simultaneously takes into account both triaxiality and reflection asymmetry. Results: Breaking axial symmetry and parity turns out to be crucial for a realistic estimate of collective action; it results in lowering SF lifetimes by more than 7 orders of magnitude in some cases. We predict two competing SF modes: reflection symmetric modes and reflection asymmetric modes. Conclusions: The shortest-lived SH isotopes decay by SF; they are expected to lie in a narrow corridor formed by 280Hs, 284Fl, and 118284Uuo that separates the regions of SH nuclei synthesized in cold-fusion and hot-fusion reactions. The region of long-lived SH nuclei is expected to be centered on 294Ds with a total half-life of 1.5 days. Our survey provides a solid benchmark for the future improvements of self-consistent SF calculations in the region of SH nuclei.

Staszczak, A, [UTK/ORNL/Inst. Physics, Maria Curie-Sklodowska University, Poland; Baran, A. [UTK/ORNL/Inst. Physics, Maria Curie-Sklodowska University, Poland; Nazarewicz, Witold [UTK/ORNL/University of Warsaw

2013-01-01T23:59:59.000Z

240

Estimated Cancer Risks Associated with Dermal Exposure to Mineral Oil Containing PCB Concentrations of 50 ppm or Less  

Science Conference Proceedings (OSTI)

The excess lifetime cancer risks (ELCRs) from dermal exposures to low levels of polychlorinated biphenyls (PCBs) (that is, 50 ppm or less) in mineral oil were determined for utility workers involved in four different work activities related to mineral oil spill cleanup and the maintenance of breakers and transformers. Two risk calculations were made for each work activity: reasonable maximum exposure (RMaxE) scenarios using conservative to highly conservative parameters and central tendency exposure (CTE...

2011-08-17T23:59:59.000Z

Note: This page contains sample records for the topic "incremental lifetime cancer" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


241

Cancer in Australia  

E-Print Network (OSTI)

statistics and information agency. The Institute’s mission is better health and wellbeing for Australians through better health and welfare statistics and information. The Australasian Association of Cancer Registries (AACR) is a collaborative body representing state and territory cancer registries in Australia and New Zealand. Most are members of the International Association of Cancer Registries. The AACR was formed in November 1982 to provide a formal mechanism for promoting uniformity of collection, classification and collation of cancer data. The objectives of the AACR are to: • Achieve national agreement on cancer-specific data definitions and coding and to encourage compliance with such agreements. As far as possible, data definitions and coding should be consistent with existing International Association of Cancer Registries (IACR) protocols and conventions. Facilitate the production of Australian, state and territory and national statistical publications on cancer that are comparable with each other and with international statistical publications. Improve the operational efficiency, and data completeness and quality, of the state and territory and New Zealand cancer registries through collaborative sharing of information. Contribute to national cancer control development in Australia and New Zealand through the regular and timely publication of local and national cancer statistics and the provision of data for cancer control research and health promotion. Contribute national data to international publications of the IACR. Contribute to international cancer coding and statistical analysis developments via members ’ involvement with IACR. Facilitate national epidemiological research projects on cancer (given appropriate local and AIHW ethics committee approvals).CANCER SERIES Number 28

unknown authors

2004-01-01T23:59:59.000Z

242

Cancer Due to Prolonged Inflammation  

E-Print Network (OSTI)

Development. Molecular Cancer Research 4.221 (2006): 5-261.direction of future cancer research is to better understand

Lingampalli, Nithya

2013-01-01T23:59:59.000Z

243

US/UK second level panel discussions on the health and value of: Ageing and lifetime predictions (u)  

SciTech Connect

Many healthy physics, engineering, and materials exchanges are being accomplished in ageing and lifetime prediction that directly supports US and UK Stockpile Management Programs. Lifetime assessment studies of silicon foams under compression - Joint AWE/LANLlLLNL study of compression set in stress cushions completed. Provides phenomenological prediction out to 50 years. Polymer volatile out-gassing studies - New exchange on the out-gassing of Ethylene Vinyl Acetate (EVA) using isotopic {sup 13}C labeling studies to interrogate mechanistic processes. Infra-red (IR) gas cell analytical capabilities developed by AWE will be used to monitor polymer out-gassing profiles. Pu Strength ageing Experiments and Constitutive Modeling - In recently compared modeling strategies for ageing effects on Pu yield strength at high strain rates, a US/UK consensus was reached on the general principle that the ageing effect is additive and not multiplicative. The fundamental mechanisms for age-strengthening in Pu remains unknown. Pu Surface and Interface Reactions - (1) US/UK secondment resulted in developing a metal-metal oxide model for radiation damaged studies consistent with a Modified Embedded Atom Method (MEAM) potential; and (2) Joint US/UK collaboration to study the role of impurities in hydride initiation. Detonator Ageing (wide range of activities) - (1) Long-term ageing study with field trials at Pantex incorporating materials from LANL, LLNL, SNL and AWE; (2) Characterization of PETN growth to detonation process; (3) Detonator performance modeling; and (4) Performance fault tree analysis. Benefits are a unified approach to lifetime prediction that Includes: materials characterization and the development of ageing models through improved understanding of the relationship between materials properties, ageing properties and detonator performance.

Castro, Richard G [Los Alamos National Laboratory

2011-01-18T23:59:59.000Z

244

The Post-Shock Chemical Lifetimes of Outflow Tracers and a Possible New Mechanism to Produce Water Ice Mantles  

E-Print Network (OSTI)

We have used a coupled time-dependent chemical and dynamical model to investigate the lifetime of the chemical legacy left in the wake of C-type shocks. We concentrate this study on the chemistry of H2O and O2, two molecules which are predicted to have abundances that are significantly affected in shock-heated gas. Two models are presented: (1) a three-stage model of pre-shock, shocked, and post-shock gas; and (2) a Monte-Carlo cloud simulation where we explore the effects of stochastic shock activity on molecular gas over a cloud lifetime. In agreement with previous studies, we find that shock velocities in excess of 10 km s^-1 are required to convert all of the oxygen not locked in CO into H2O before the gas has an opportunity to cool. For pure gas-phase models the lifetime of the high water abundances, or ``H2O legacy'', in the post-shock gas is 4 - 7 x 10^5 years. Through the Monte Carlo cloud simulation we demonstrate that the time-average abundance of H2O is a sensitive function of the frequency of shocks. Thus we predict that the abundance of H2O and other known outflow tracers can be used to trace the history of shock activity in molecular gas. For gas-grain models we find that the abundance of water-ice on grain surfaces can be quite large and is comparable to that observed in molecular clouds. This offers a possible alternative method to create water mantles without resorting to grain surface chemistry: gas heating and chemical modification due to a C-type shock and subsequent depletion of the gas-phase species onto grain mantles.

Edwin A. Bergin; Gary J. Melnick; David A. Neufeld

1998-03-30T23:59:59.000Z

245

Shark cartilage and cancer  

NLE Websites -- All DOE Office Websites (Extended Search)

speculation in the past that there may be some factor in shark's cartilage that prevents cancer, recent research by the National Cancer Institute could not confirm this, and there...

246

Soy and breast cancer  

Science Conference Proceedings (OSTI)

Are soy foods safe for breast cancer patients? Soy is a rich source of isoflavones (primarily genistein, daidzein, and glycitein). The standard oral therapy undertaken after initial treatment (known as “adjuvant therapy”) for estrogen-sensitive cancers is

247

New Mass and Lifetime Measurements of $^{152}$Sm Projectile Fragments with Time-Resolved Schottky Mass Spectrometry  

E-Print Network (OSTI)

The FRS-ESR facilities at GSI provide unique conditions for precision measurements with stored exotic nuclei over a large range in the chart of nuclides. In the present experiment the exotic nuclei were produced via fragmentation of $^{152}$Sm projectiles in a thick beryllium target at 500-600 MeV/u, separated in-flight with the fragment separator FRS, and injected into the storage-cooler ring ESR. Mass and lifetime measurements have been performed with bare and few-electron ions. The experiment and first results will be presented in this contribution.

Litvinov, Y A; Geissel, H; Weick, H; Beckert, Karl; Beller, Peter; Boutin, D; Brandau, C; Chen, L; Klepper, O; Knöbel, R; Kozhuharov, C; Kurcewicz, J; Litvinov, S A; Mazzocco, M; Münzenberg, G; Nociforo, C; Nolden, F; Plass, W; Scheidenberger, C; Steck, Markus; Sun, B; Winkler, M; Litvinov, Yu.A.

2005-01-01T23:59:59.000Z

248

Value Proposition for High Lifetime (p-type) and Thin Silicon Materials in Solar PV Applications: Preprint  

DOE Green Energy (OSTI)

Most silicon PV road maps forecast a continued reduction in wafer thickness, despite rapid declines in the primary incentive for doing so -- polysilicon feedstock price. Another common feature of most silicon-technology forecasts is the quest for ever-higher device performance at the lowest possible costs. The authors present data from device-performance and manufacturing- and system-installation cost models to quantitatively establish the incentives for manufacturers to pursue advanced (thin) wafer and (high efficiency) cell technologies, in an age of reduced feedstock prices. This analysis exhaustively considers the value proposition for high lifetime (p-type) silicon materials across the entire c-Si PV supply chain.

Goodrich, A.; Woodhouse, M.; Hacke, P.

2012-06-01T23:59:59.000Z

249

ENVIRONMENTAL CANCER RISK  

E-Print Network (OSTI)

This report is submitted to the President of the United States in fulfillment of the obligations of the President’s Cancer Panel to appraise the National Cancer Program as established in accordance with the National Cancer Act of 1971 (P.L. 92-218), the

Margaret L. Kripke, Ph.D.; Abby B. S, Ph.D.; Suzanne H. Reuben

2010-01-01T23:59:59.000Z

250

Charge Lifetime Study of K2CsSb Photocathode Inside a JLAB DC High Voltage Gun  

SciTech Connect

Two photocathodes are frequently considered for generating high average current electron beams and/or beams with high brightness for current and future accelerator applications: GaAs:Cs and K2CsSb. Each photocathode has advantages and disadvantages, and need to demonstrate performance at 'production' accelerator facilities. To this end a K2CsSb photocathode was manufactured at Brookhaven National Lab and delivered to Jefferson Lab within a compact vacuum apparatus at pressure {approx} 5 x 10{sup -11} Torr. This photocathode was installed inside a dc high voltage photogun biased at voltages up to 200 kV, and illuminated with laser light at 440 or 532 nm, to generate beams up to 20 mA. Photocathode charge lifetime measurements indicate that under some conditions this cathode has exceptionally high charge lifetime, without measurable QE decay, even from the center of the photocathode where operation using GaAs photocathodes is precluded due to ion bombardment. These studies also suggest a complex QE decay mechanism likely related to chemistry and localized heating via the laser beam.

Mammei, R.; Rao, T.; Suleiman, R.; Poelker, M.; Smedley, J.; McCarter, J.L.

2011-10-01T23:59:59.000Z

251

Distribution of lifetimes of kinetochore-microtubule attachments:interplay of energy landscape, molecular motors and microtubule (de-)polymerization  

E-Print Network (OSTI)

Before a cell divides into two daughter cells, the chromosomes are replicated resulting in two sister chromosomes embracing each other. Each sister chromosome is bound to a separate proteinous structure, called kinetochore (kt), that captures the tip of a filamentous protein, called microtubule (MT). Two oppositely oriented MTs pull the two kts attached to two sister chromosomes thereby pulling the two sisters away from each other. Here we theoretically study an even simpler system, namely an isolated kt coupled to a single MT; this system mimics an {\\it in-vitro} experiment where a single kt-MT attachment is reconstituted using purified extracts from budding yeast. Our models not only account for the experimentally observed "catch-bond-like" behavior of the kt-MT coupling, but also make new predictions on the probability distribution of the lifetimes of the attachments. In principle, our new predictions can be tested by analyzing the data collected in the {\\it in-vitro} experiments provided the experiment is repeated sufficiently large number of times. Our theory provides a deep insight into the effects of (a) size, (b) energetics, and (c) stochastic kinetics of the kt-MT coupling on the distribution of the lifetimes of these attachments.

Ajeet K. Sharma; Blerta Shtylla; Debashish Chowdhury

2013-10-06T23:59:59.000Z

252

Incidence of non-lung solid cancers in Czech uranium miners: A case-cohort study  

Science Conference Proceedings (OSTI)

Objectives: Uranium miners are chronically exposed to radon and its progeny, which are known to cause lung cancer and may be associated with leukemia. This study was undertaken to evaluate risk of non-lung solid cancers among uranium miners in Pribram region, Czech Republic. Methods: A retrospective stratified case-cohort study in a cohort of 22,816 underground miners who were employed between 1949 and 1975. All incident non-lung solid cancers were ascertained among miners who worked underground for at least 12 months (n=1020). A subcohort of 1707 subjects was randomly drawn from the same population by random sampling stratified on age. The follow-up period lasted from 1977 to 1996. Results: Relative risks comparing 180 WLM (90th percentile) of cumulative lifetime radon exposure to 3 WLM (10th percentile) were 0.88 for all non-lung solid cancers combined (95% CI 0.73-1.04, n=1020), 0.87 for all digestive cancers (95% CI 0.69-1.09, n=561), 2.39 for gallbladder cancer (95% CI 0.52-10.98, n=13), 0.79 for larynx cancer (95% CI 0.38-1.64, n=62), 2.92 for malignant melanoma (95% CI 0.91-9.42, n=23), 0.84 for bladder cancer (95% CI 0.43-1.65, n=73), and 1.13 for kidney cancer (95% CI 0.62-2.04, n=66). No cancer type was significantly associated with radon exposure; only malignant melanoma and gallbladder cancer showed elevated but non-significant association with radon. Conclusions: Radon was not significantly associated with incidence of any cancer of interest, although a positive association of radon with malignant melanoma and gallbladder cancer cannot be entirely ruled out. - Research highlights: {yields} Uranium miners are chronically exposed to radon. {yields} We evaluate risk of non-lung solid cancers among uranium miners. {yields} No cancer type was significantly associated with radon exposure. {yields} Malignant melanoma and gallbladder cancer showed non-significant elevated risk.

Kulich, M., E-mail: kulich@karlin.mff.cuni.cz [Department of Statistics, Faculty of Mathematics and Physics, Charles University, Sokolovska 83, CZ-186 75 Praha 8 (Czech Republic); Rericha, V. [Regional Hospital Pribram (Czech Republic)] [Regional Hospital Pribram (Czech Republic); Rericha, R. [Center of Epidemiological Studies, Pribram (Czech Republic)] [Center of Epidemiological Studies, Pribram (Czech Republic); Shore, D.L. [Westat, Inc., Durham, NC (United States)] [Westat, Inc., Durham, NC (United States); Sandler, D.P. [Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, NC (United States)] [Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, NC (United States)

2011-04-15T23:59:59.000Z

253

Defining the Critical Hurdles in Cancer Immunotherapy  

E-Print Network (OSTI)

Australia. Ovarian Cancer Research Center, University ofal: New models for cancer research: human cancer stem cellAmerican Association for Cancer Research 2010, 16:2861-71.

2011-01-01T23:59:59.000Z

254

The Value Proposition for High Lifetime (p-type) and Thin Silicon Materials in Solar PV Applications: Preprint  

NLE Websites -- All DOE Office Websites (Extended Search)

Proposition for High Proposition for High Lifetime (p-type) and Thin Silicon Materials in Solar PV Applications Preprint Alan Goodrich, Michael Woodhouse, and Peter Hacke Presented at the 2012 IEEE Photovoltaic Specialists Conference Austin, Texas June 3-8, 2012 Conference Paper NREL/CP-6A20-55477 June 2012 NOTICE The submitted manuscript has been offered by an employee of the Alliance for Sustainable Energy, LLC (Alliance), a contractor of the US Government under Contract No. DE-AC36-08GO28308. Accordingly, the US Government and Alliance retain a nonexclusive royalty-free license to publish or reproduce the published form of this contribution, or allow others to do so, for US Government purposes. This report was prepared as an account of work sponsored by an agency of the United States government.

255

Determination of the 5d6s 3D1 state lifetime and blackbody radiation clock shift in Yb  

E-Print Network (OSTI)

The Stark shift of the ytterbium optical clock transition due to room temperature blackbody radiation is dominated by a static Stark effect, which was recently measured to high accuracy [J. A. Sherman et al., Phys. Rev. Lett. 108, 153002 (2012)]. However, room temperature operation of the clock at 10^{-18} inaccuracy requires a dynamic correction to this static approximation. This dynamic correction largely depends on a single electric dipole matrix element for which theoretically and experimentally derived values disagree significantly. We determine this important matrix element by two independent methods, which yield consistent values. Along with precise radiative lifetimes of 6s6p 3P1 and 5d6s 3D1, we report the clock's blackbody radiation shift to 0.05% precision.

Beloy, K; Lemke, N D; Hinkley, N; Oates, C W; Ludlow, A D

2012-01-01T23:59:59.000Z

256

Literature review of the lifetime of DOE materials: Aging of plastic bonded explosives and the explosives and polymers contained therein  

SciTech Connect

There are concerns about the lifetime of the nation`s stockpile of high explosives (HEs) and their components. The DOE`s Core Surveillance and Enhanced Surveillance programs specifically target degradation of HE, binders, and plastic-bonded explosives (PBXs) for determination of component lifetimes and handling procedures. The principal goal of this project is to identify the decomposition mechanisms of HEs, plasticizers, and plastic polymer binders resulting from exposure to ionizing radiation, heat, and humidity. The primary HEs of concern are 1,3,5-triamino-2,4,6-trinitrobenzene (TATB) and 1,3,5,7-tetranitro-1,3,5,7-tetraazocyclooctane (HMX). Hexahydro-1,3,5-triazine (RDX) is closely related to these two compounds and is also included in the literature review. Both Kel-F 800 and Estane are polymers of interest. A stabilizer, Irganox 1010, and an energetic plasticizer that is a blend of acetaldehyde 2,2-dinitropropyl acetal, are also of interest, but the focus of this report will be on the explosives and polymers. This presents a literature review that provides background on the synthesis, degradation, and techniques to analyze TATB, HMX, RDX, Kel-F 800, Estane, and the PBXs of these compounds. As there are many factors that can influence degradation of materials, the degradation discussion will be divided into sections based on each factor and how it might affect the degradation mechanism. The factors reviewed that influence the degradation of these materials are exposure to heat, UV- and {gamma}-irradiation, and the chemistry of these compounds. The report presents a recently compiled accounting of the available literature. 80 refs., 7 figs.

Burgess, C.E.; Woodyard, J.D. [West Texas A and M Univ., Canyon, TX (United States); Rainwater, K.A. [Texas Tech Univ., Lubbock, TX (United States); Lightfoot, J.M. [Pantex Plant, Amarillo, TX (United States); Richardson, B.R. [Engineered Carbons, Inc., Borger, TX (United States)

1998-09-01T23:59:59.000Z

257

Cancer survivorship : understanding the issues faced by cancer survivors.  

E-Print Network (OSTI)

??International research on cancer survivorship has started to identify a range of issues that affect cancer survivors physically, mentally, emotionally and spiritually. These issues can… (more)

Hayward, Penelope Anne

2010-01-01T23:59:59.000Z

258

A system to test the effects of materials on the electron drift lifetime in liquid argon and observations on the effect of water  

SciTech Connect

A materials test system (MTS) has been developed at FNAL to assess the suitability of materials for use in a large liquid argon time projection chamber. During development of the MTS, it was noted that controlling the cryostat pressure with a 'raining' condenser reduced the electron drift lifetime in the liquid argon. The effect of condensing has been investigated using a series of passive materials to filter the condensate. We report the results of these studies and of tests on different candidate materials for detector construction. The inferred reduction of electron drift lifetime by water concentrations in the parts per trillion is of particular interest.

Andrews, R.; Jaskierny, W.; Jostlein, H.; Kendziora, C.; Pordes, S.; Tope, T.; /Fermilab

2009-07-01T23:59:59.000Z

259

Observed Changes in the Lifetime and Amplitude of the Madden–Julian Oscillation Associated with Interannual ENSO Sea Surface Temperature Anomalies  

Science Conference Proceedings (OSTI)

The Madden–Julian oscillation (MJO) is analyzed using the reanalysis zonal wind– and satellite outgoing longwave radiation–based indices of Wheeler and Hendon for the 1974–2005 period. The average lifetime of the MJO events varies with season (36 ...

Benjamin Pohl; Adrian J. Matthews

2007-06-01T23:59:59.000Z

260

Enhancement of electron lifetime in dye-sensitized solar cells using anodically grown TiO2 nanotube/nanoparticle composite photoanodes  

Science Conference Proceedings (OSTI)

Dye-sensitized solar cells (DSCs) based on TiO"2 nanotube/nanoparticle (NT/NP) composite photoanodes were fabricated including different NT content into the NP network. The NPs expose large surface area for the dye anchoring, while the incorporated nanotubes ... Keywords: Anodic oxidation, Charge transport, Dye-sensitized solar cell, Electron lifetime, TiO2 nanotubes

Andrea Lamberti, Adriano Sacco, Stefano Bianco, Marzia Quaglio, Diego Manfredi, Candido Fabrizio Pirri

2013-11-01T23:59:59.000Z

Note: This page contains sample records for the topic "incremental lifetime cancer" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


261

Measurement of D-D-bar mixing using the ratio of lifetimes for the decays D-->K- pi + and K+K-  

E-Print Network (OSTI)

We measure the rate of D0-D[over-bar] 0 mixing with the observable yCP=(?Kpi/?KK)-1, where ?KK and ?Kpi are, respectively, the mean lifetimes of CP-even D0-->K+K- and CP-mixed D0-->K-pi+ decays, using a data sample of ...

Fisher, Peter H.

262

Effects of Cu Diffusion from ZnTe:Cu/Ti Contacts on Carrier Lifetime of CdS/CdTe Thin Film Solar Cells: Preprint  

DOE Green Energy (OSTI)

We study the performance of CdS/CdTe thin film PV devices processed with a ZnTe:Cu/Ti contact to investigate how carrier lifetime in the CdTe layer is affected by Cu diffusion from the contact.

Gessert, T. A.; Metzger, W. K.; Asher, S. E.; Young, M. R.; Johnston, S.; Dhere, R. G.; Duda, A.

2008-05-01T23:59:59.000Z

263

Roles for Cardiac MyBP-C in Maintaining Myofilament Lattice Rigidity and Prolonging Myosin Cross-Bridge Lifetime  

Science Conference Proceedings (OSTI)

We investigated the influence of cardiac myosin binding protein-C (cMyBP-C) and its constitutively unphosphorylated status on the radial and longitudinal stiffnesses of the myofilament lattice in chemically skinned myocardial strips of the following mouse models: nontransgenic (NTG), effective null for cMyBP-C (t/t), wild-type cMyBP-C expressed into t/t (WT{sub t/t}), and constitutively unphosphorylated cMyBP-C (AllP{sub -t/t}). We found that the absence of cMyBP-C in the t/t and the unphosphorylated cMyBP-C in the AllP{sub -t/t} resulted in a compressible cardiac myofilament lattice induced by rigor not observed in the NTG and WT{sub t/t}. These results suggest that the presence and phosphorylation of the N-terminus of cMyBP-C provides structural support and radial rigidity to the myofilament lattice. Examination of myofilament longitudinal stiffness under rigor conditions demonstrated a significant reduction in cross-bridge-dependent stiffness in the t/t compared with NTG controls, but not in the AllP{sub -t/t} compared with WT{sub t/t} controls. The absence of cMyBP-C in the t/t and the unphosphorylated cMyBP-C in the AllP{sub -t/t} both resulted in a shorter myosin cross-bridge lifetime when myosin isoform was controlled. These data collectively suggest that cMyBP-C provides radial rigidity to the myofilament lattice through the N-terminus, and that disruption of the phosphorylation of cMyBP-C is sufficient to abolish this structural role of the N-terminus and shorten cross-bridge lifetime. Although the presence of cMyBP-C also provides longitudinal rigidity, phosphorylation of the N-terminus is not necessary to maintain longitudinal rigidity of the lattice, in contrast to radial rigidity.

Palmer, B.M.; Sadayappan, S.; Wang, Y.; Weith, A.E.; Previs, M.J.; Bekyarova, T.; Irving, T.C.; Robbins, J.; Maughan, D.W. (Vermont)

2011-10-06T23:59:59.000Z

264

Canadian Expert Panel on Tobacco Smoke and Breast Cancer Risk  

E-Print Network (OSTI)

Family Institute for Breast Cancer Research Ontario CancerInternational Agency for Research on Cancer, 2000. CancerThe Canadian Cancer Registries Epidemiology Research Group,

2009-01-01T23:59:59.000Z

265

Testing and Analysis for Lifetime Prediction of Crystalline Silicon PV Modules Undergoing Degradation by System Voltage Stress: Preprint  

DOE Green Energy (OSTI)

Acceleration factors are calculated for crystalline silicon PV modules under system voltage stress by comparing the module power during degradation outdoors to that in accelerated testing at three temperatures and 85% relative humidity. A lognormal analysis is applied to the accelerated lifetime test data considering failure at 80% of the initial module power. Activation energy of 0.73 eV for the rate of failure is determined, and the probability of module failure at an arbitrary temperature is predicted. To obtain statistical data for multiple modules over the course of degradation in-situ of the test chamber, dark I-V measurements are obtained and transformed using superposition, which is found well suited for rapid and quantitative evaluation of potential-induced degradation. It is determined that shunt resistance measurements alone do not represent the extent of power degradation. This is explained with a two-diode model analysis that shows an increasing second diode recombination current and ideality factor as the degradation in module power progresses. Failure modes of the modules stressed outdoors are examined and compared to those stressed in accelerated tests.

Hacke, P.; Smith, R.; Terwiliger, K.; Glick, S.; Jordan, D.; Johnston, S.; Kempe, M.; Kurtz, S.

2012-07-01T23:59:59.000Z

266

Second cancer incidence risk estimates using BEIR VII models for standard and complex external beam radiotherapy for early breast cancer  

Science Conference Proceedings (OSTI)

Purpose: To compare organ specific cancer incidence risks for standard and complex external beam radiotherapy (including cone beam CT verification) following breast conservation surgery for early breast cancer.Method: Doses from breast radiotherapy and kilovoltage cone beam CT (CBCT) exposures were obtained from thermoluminescent dosimeter measurements in an anthropomorphic phantom in which the positions of radiosensitive organs were delineated. Five treatment deliveries were investigated: (i) conventional tangential field whole breast radiotherapy (WBRT), (ii) noncoplanar conformal delivery applicable to accelerated partial beast irradiation (APBI), (iii) two-volume simultaneous integrated boost (SIB) treatment, (iv) forward planned three-volume SIB, and (v) inverse-planned three volume SIB. Conformal and intensity modulated radiotherapy methods were used to plan the complex treatments. Techniques spanned the range from simple methods appropriate for patient cohorts with a low cancer recurrence risk to complex plans relevant to cohorts with high recurrence risk. Delineated organs at risk included brain, salivary glands, thyroid, contralateral breast, left and right lung, esophagus, stomach, liver, colon, and bladder. Biological Effects of Ionizing Radiation (BEIR) VII cancer incidence models were applied to the measured mean organ doses to determine lifetime attributable risk (LAR) for ages at exposure from 35 to 80 yr according to radiotherapy techniques, and included dose from the CBCT imaging. Results: All LAR decreased with age at exposure and were lowest for brain, thyroid, liver, and bladder (cancer incidence for organs distant from the treated breast, or the contralateral breast where appropriate plan constraints are applied. Complex SIB treatments are predicted to increase the risk of second cancer incidence in the lungs compared to standard whole breast radiotherapy; this is outweighed by the threefold reduction in 5 yr local recurrence risk for patients of high risk of recurrence, and young age, from the use of radiotherapy. APBI may have a favorable impact on risk of second cancer in the contralateral breast and lung for older patients at low risk of recurrence. Intensive use of IGRTincreased the estimated values of LAR but these are dominated by the effect of the dose from the radiotherapy, and any increase in LAR from IGRT is much lower than the models' uncertainties.

Donovan, E. M.; James, H.; Bonora, M.; Yarnold, J. R.; Evans, P. M. [Joint Department of Physics, Royal Marsden NHS Foundation Trust and Institute of Cancer Research, Sutton SM2 5PT (United Kingdom); Physics Department, Ipswich Hospital NHS Foundation Trust, Ipswich IP4 5PD (United Kingdom); Department of Academic Radiotherapy, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton SM2 5PT, United Kingdom and School of Radiotherapy, University of Milan, Milan 20122 (Italy); Department of Academic Radiotherapy, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton SM2 5PT (United Kingdom); Centre for Vision Speech and Signal Processing, University of Surrey, Guildford GU2 7XH (United Kingdom)

2012-10-15T23:59:59.000Z

267

Electrogenerated Chemiluminescence and Fluorescence Lifetime Spatial Heterogeneity of Poly (2-methoxy-5-(2-ethylhexyloxy)-1, 4-phenylenevinylene) in Presence of [6,6]-phenyl-C61-butyric Acid Methyl Ester  

SciTech Connect

In this paper, we studied the luminescence property and fluorescence lifetime mapping of MEH-PPV/PCBM system by using electrogenerated chemiluminescence (ECL) and time-correlated single photo counting (TC-SPC) technologies. The ECL results showed that the oxidation peak of MEH-PPV near 0.7 V (vs. SCE) and ECL response of films shifted positively towards 1.2 V when in the presence of PCBM. At the same time, the oxidation peak current density of MEH-PPV increases while the ECL response decreased with the loading of PCBM in the composite films. The fluorescence lifetime images clearly show that the lifetime fluctuation is effected by different substrates and MEH-PPV/PCBM ratios. Meanwhile, the lifetime of MEH-PPV decreases with the increasing of film thickness. The lifetimes of MEH-PPV films on TiO2 substrate are lower than them of films on cover slips.

Geng, Hongwei; Pan, Shanlin; Hu, Dehong

2013-04-01T23:59:59.000Z

268

LED Lifetime Measurements  

Science Conference Proceedings (OSTI)

... at a time,” Zong says, providing information about how ... DOE's Energy Star program requires accreditation of ... products available on market, and then ...

2013-08-16T23:59:59.000Z

269

Northeast Regional Cancer Institute's Cancer Surveillance and Risk Factor Program  

Science Conference Proceedings (OSTI)

OBJECTIVES The Northeast Regional Cancer Institute is conducting a program of ongoing epidemiologic research to address cancer disparities in northeast Pennsylvania. Of particular concern are disparities in the incidence of, stage at diagnosis, and mortality from colorectal cancer. In northeast Pennsylvania, age-adjusted incidence and mortality rates for colorectal cancer are higher, and a significantly smaller proportion of new colorectal cancer cases are diagnosed with local stage disease than is observed in comparable national data. Further, estimates of the prevalence of colorectal cancer screening in northeast Pennsylvania are lower than the US average. The Northeast Regional Cancer Institute’s research program supports surveillance of common cancers, investigations of cancer risk factors and screening behaviors, and the development of resources to further cancer research in this community. This project has the following specific objectives: I. To conduct cancer surveillance in northeast Pennsylvania. a. To monitor incidence and mortality for all common cancers, and colorectal cancer, in particular, and b. To document changes in the stage at diagnosis of colorectal cancer in this high-risk, underserved community. II. To conduct a population-based study of cancer risk factors and screening behavior in a six county region of northeast Pennsylvania. a. To monitor and document changes in colorectal cancer screening rates, and b. To document the prevalence of cancer risk factors (especially factors that increase the risk of colorectal cancer) and to identify those risk factors that are unusually common in this community. APPROACH Cancer surveillance was conducted using data from the Northeast Regional Cancer Institute’s population-based Regional Cancer Registry, the Pennsylvania Cancer Registry, and NCI’s SEER program. For common cancers, incidence and mortality were examined by county within the region and compared to data for similar populations in the US. For colorectal cancer, the stage at diagnosis of cases diagnosed in northeast Pennsylvania was compared to data from prior years. A population-based interview study of healthy adults was conducted to document the status of cancer screening and to estimate the prevalence of established cancer risk factors in this community. This study is similar in design to that used by the Centers for Disease Control and Prevention’s (CDC) Behavioral Risk Factor Surveillance System (BRFSS). EXPERIMENTAL METHODS AND PROCEDURES: This program includes two distinct but related projects. The first project uses existing data to conduct cancer surveillance in northeast Pennsylvania, and the second is a population-based study of cancer risk factors and cancer screening behaviors in this same population. HUMAN SUBJECTS CONSIDERATIONS This program includes two projects: cancer surveillance and a population-based study of cancer risk factors and screening behavior. The cancer surveillance project involves only the use of existing aggregate data or de-identified data. As such, the surveillance project is exempt from human subjects considerations. The study of cancer risk factors and screening behaviors includes data from a random sample of adult residents of northeast Pennsylvania who are 18 or more years of age. All races, ethnicities and both sexes are included in proportion to their representation in the population. Subjects are interviewed anonymously by telephone; those who are unable to complete an interview in English are ineligible. This project has been reviewed and approved by the Scranton-Temple Residency Program IRB (IRB00001355), which is the IRB for the Northeast Regional Cancer Institute.

Lesko, Samuel M.

2007-07-31T23:59:59.000Z

270

A Detailed Analysis and Monte Carlo Simulation of the Neutron Lifetime Experiment S. Arzumanov et al., Phys. Lett. B 483 (2000) 15  

E-Print Network (OSTI)

We performed a detailed analysis and the Monte Carlo simulation of the neutron lifetime experiment [S. Arzumanov et al., Phys. Lett. B 483 (2000) 15] because of the strong disagreement by 5.6 standard deviations between the results of this experiment and our experiment [A. Serebrov et al., Phys. Lett. B 605 (2005) 72]. We found a few effects which were not taken into account in the experiment [S. Arzumanov et al., Phys. Lett. B 483 (2000) 15]. The possible correction is -5.5 s with uncertainty of 2.4 s which comes from initial data knowledge. We assume that after taking into account this correction the result of work [S. Arzumanov et al., Phys. Lett. B 483 (2000) 15] for neutron lifetime 885.4 +/- 0.9stat +/- 0.4syst s could be corrected to 879.9 +/- 0.9stat +/- 2.4syst s.

Fomin, A K

2010-01-01T23:59:59.000Z

271

Measurement of the B_d0 lifetime using B_d0 to J/psi K0_S decays at Dzero  

SciTech Connect

This thesis describes a measurement of the B{sub d}{sup 0} lifetime in the decay to (J/{psi}K{sub S}{sup 0}), using 114 pb{sup -1} of data collected by the D0 experiment at the Tevatron from October 15, 2002, to June 10, 2003. The measurement is motivated by the tests of the Standard Model that it makes possible. These include tests of Heavy Quark Effective Theory predicting B-meson lifetimes, and of the complex phase in the CKM-matrix as the source of CP-violation in B{sub d}{sup 0} decays to (J/{psi}K{sub S}{sup 0}).

Balm, Paul W.; /Amsterdam U.

2004-12-01T23:59:59.000Z

272

Cancer risk among atomic bomb survivors. The RERF Life Span Study. Radiation Effects Research Foundation  

SciTech Connect

This article summarizes the risk of cancer among the survivors of the atomic bombing of Hiroshima and Nagasaki. We focus primarily on the risk of death from cancer among individuals in the Life Span Study sample of the Radiation Effects Research Foundation from 1950 through 1985 based on recently revised dosimetry procedures. We report the risk of cancer other than leukemia among the atomic bomb survivors. We note that the number of excess deaths of radiation-induced malignant tumors other than leukemia increases with age. Survivors who were exposed in the first or second decade of life have just entered the cancer-prone age and have so far exhibited a high relative risk in association with radiation dose. Whether the elevated risk will continue or will fall with time is not yet clear, although some evidence suggests that the risk may be declining. It is important to continue long-term follow-up of this cohort to document the changes with time since exposure and to provide direct rather than projected risks over the lifetime of an exposed individual.

Shimizu, Y.; Schull, W.J.; Kato, H. (Radiation Effects Research Foundation, Hiroshima (Japan))

1990-08-01T23:59:59.000Z

273

Proteomics for cancer biomarker discovery  

E-Print Network (OSTI)

Background: If we are to successfully treat cancer, we must understand the biologic underpinnings in conjunction with early diagnosis. Genome-wide expression studies have advanced the research of many cancers. Nevertheless, ...

Volchenboum, Samuel Louis

2007-01-01T23:59:59.000Z

274

Value of Diffusion-Weighted Magnetic Resonance Imaging for Prediction and Early Assessment of Response to Neoadjuvant Radiochemotherapy in Rectal Cancer: Preliminary Results  

Science Conference Proceedings (OSTI)

Purpose: To evaluate diffusion-weighted magnetic resonance imaging (DWI) for response prediction before and response assessment during and early after preoperative radiochemotherapy (RCT) for locally advanced rectal cancer (LARC). Methods and Materials: Twenty patients receiving RCT for LARC underwent MRI including DWI before RCT, after 10-15 fractions and 1 to 2 weeks before surgery. Tumor volume and apparent diffusion coefficient (ADC; b-values: 0-1000 s/mm{sup 2}) were determined at all time points. Pretreatment tumor ADC and volume, tumor ADC change ( Increment ADC), and volume change ( Increment V) between pretreatment and follow-up examinations were compared with histopathologic findings after total mesorectal excision (pathologic complete response [pCR] vs. no pCR, ypT0-2 vs. ypT3-4, T-downstaging or not). The discriminatory capability of pretreatment tumor ADC and volume, Increment ADC, and Increment V for the detection of pCR was compared with receiver operating characteristics analysis. Results: Pretreatment ADC was significantly lower in patients with pCR compared with patients without (in mm{sup 2}/s: 0.94 {+-} 0.12 Multiplication-Sign 10{sup -3} vs. 1.19 {+-} 0.22 Multiplication-Sign 10{sup -3}, p = 0.003), yielding a sensitivity of 100% and specificity of 86% for detection of pCR. The volume reduction during and after RCT was significantly higher in patients with pCR compared with patients without (in %: {Delta}V{sub during}: -62 {+-} 16 vs. -33 {+-} 16, respectively, p = 0.015; and {Delta}V{sub post}: -86 {+-} 12 vs. -60 {+-} 21, p = 0.012), yielding a sensitivity of 83% and specificity of 71% for the {Delta}V{sub during} and, respectively, 83% and 86% for the {Delta}V{sub post}. The Increment ADC during ({Delta}ADC{sub during}) and after RCT ({Delta}ADC{sub post}) showed a significantly higher value in patients with pCR compared with patients without (in %: {Delta}ADC{sub during}: 72 {+-} 14 vs. 16 {+-} 12, p = 0.0006; and {Delta}ADC{sub post}: 88 {+-} 35 vs. 26 {+-} 19, p = 0.0011), yielding a sensitivity and specificity of 100% for the {Delta}ADC{sub during} and, respectively, 100% and 93% for the {Delta}ADC{sub post}. Conclusions: These initial findings indicate that DWI, using pretreatment ADC, {Delta}ADC{sub during}, and {Delta}ADC{sub post} may be useful for prediction and early assessment of pathologic response to preoperative RCT of LARC, with higher accuracy than volumetric measurements.

Lambrecht, Maarten, E-mail: maarten.lambrecht@uzleuven.be [Department of Radiation Oncology, UZ Gasthuisberg, Leuven (Belgium); Vandecaveye, Vincent; De Keyzer, Frederik [Department of Radiology, UZ Gasthuisberg, Leuven (Belgium); Roels, Sarah [Department of Radiation Oncology, UZ Gasthuisberg, Leuven (Belgium); Penninckx, Freddy [Department of Abdominal Surgery, UZ Gasthuisberg, Leuven (Belgium); Van Cutsem, Eric [Department of Digestive Oncology, UZ Gasthuisberg, Leuven (Belgium); Filip, Claus [Department of Radiology, UZ Gasthuisberg, Leuven (Belgium); Haustermans, Karin [Department of Radiation Oncology, UZ Gasthuisberg, Leuven (Belgium)

2012-02-01T23:59:59.000Z

275

Animal Models in Cancer Research  

Science Conference Proceedings (OSTI)

Cancer is a disorder that results in inappropriate growth of cells in the wrong place and at the wrong time. Most frequently cancer arises in older individuals and becomes problematic as it grows large enough to interrupt normal organ function, invades adjacent normal tissues disrupting their function, and spreads to other sites in the body, metastatic sites, where it causes further disabilities. Cancer arises in normal cells of our body. The environmental causes of cancer include numerous, disparate fac...

2009-12-17T23:59:59.000Z

276

Cancer in atomic bomb survivors  

SciTech Connect

This book presents information on the following topics: sampling of atomic bomb survivors and method of cancer detection in Hiroshima and Nagasaki; atomic bomb dosimetry for epidemiological studies of survivors in Hiroshima and Nagasaki; tumor and tissue registries in Hiroshima and Nagasaki; the cancer registry in Nagasaki, with atomic bomb survivor data, 1973-1977; cancer mortality; methods for study of delayed health effects of a-bomb radiation; experimental radiation carcinogenesis in rodents; leukemia, multiple myeloma, and malignant lymphoma; cancer of the thyroid and salivary glands; malignant tumors in atomic bomb survivors with special reference to the pathology of stomach and lung cancer; colorectal cancer among atomic bomb survivors; breast cancer in atomic bomb survivors; and ovarian neoplasms in atomic bomb survirors.

Shigematsu, I.; Kagan, A.

1986-01-01T23:59:59.000Z

277

Incremental Closure of Free Variable Tableaux  

Science Conference Proceedings (OSTI)

This paper presents a technique for automated theorem proving with free variable tableaux that does not require backtracking. Most existing automated proof procedures using free variable tableaux require iterative deepening and backtracking over applied ...

Martin Giese

2001-06-01T23:59:59.000Z

278

Incremental Accelerated Gradient Methods for SVM Classification ...  

E-Print Network (OSTI)

Vector Machines, Proceedings of the 2010 IEEE International Conference on Data. Mining, pp. 679-688, IEEE Computer Society, Washington, DC, USA, 2010.

279

Incremental computation and maintenance of temporal aggregates  

Science Conference Proceedings (OSTI)

Abstract.We consider the problems of computing aggregation queries in temporal databases and of maintaining materialized temporal aggregate views efficiently. The latter problem is particularly challenging since a single data update can cause aggregate ... Keywords: Access methods, Aggregation, B-tree, Segment tree, Temporal database, View maintenance

Jun Yang; Jennifer Widom

2003-10-01T23:59:59.000Z

280

Comparing Reanalyses Using Analysis Increment Statistics  

Science Conference Proceedings (OSTI)

Reanalysis data are an important source of information for hydrometeorology applications, which use data assimilation to combine an imperfect atmospheric model with uncertain observations. However, uncertainty estimates are not normally provided ...

Jean Fitzmaurice; Rafael L. Bras

2008-12-01T23:59:59.000Z

Note: This page contains sample records for the topic "incremental lifetime cancer" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


281

Modeling Sea Ice Transport Using Incremental Remapping  

Science Conference Proceedings (OSTI)

Sea ice models contain transport equations for the area, volume, and energy of ice and snow in various thickness categories. These equations typically are solved with first-order-accurate upwind schemes, which are very diffusive; with second-...

William H. Lipscomb; Elizabeth C. Hunke

2004-06-01T23:59:59.000Z

282

Incremental housing at the receding suburban fringe  

E-Print Network (OSTI)

The years from 2005-2010 brought two major events that shook the basic assumptions underlying housing delivery in the United States of America. First, Hurricane Katrina and the catastrophic flooding of New Orleans that ...

Lamb, Zachary B

2010-01-01T23:59:59.000Z

283

Incremental Network Design with Maximum Flows  

E-Print Network (OSTI)

Dec 21, 2013 ... [4] B.J. Kim, W. Kim, and B.H. Song. Sequencing ... is given by a collection S of 3-

284

Improved VSM for Incremental Text Classification  

Science Conference Proceedings (OSTI)

As a simple classification method VSM has been widely applied in text information processing field. There are some problems for traditional VSM to select a refined vector model representation

Zhen Yang; Jianjun Lei; Jian Wang; Xing Zhang; Jim Guo

2008-01-01T23:59:59.000Z

285

Incremental Network Design with Shortest Paths  

E-Print Network (OSTI)

We compare the following three strategies ... For the third strategy we get .... Rather than considering network expansion, we can consider network maintenance.

286

Incrementality, Half-life, and Threshold Optimization  

Science Conference Proceedings (OSTI)

... In A. Kent, editor, Encyclopedia of Library and Information Science. Marcel Dekker, Inc., New York, Basel, 2000. To appear. ...

2001-02-09T23:59:59.000Z

287

Incremental and Encoding Formulations for Mixed Integer ...  

E-Print Network (OSTI)

Apr 1, 2013 ... aTepper School of Business, Carnegie Mellon University, 5000 Forbes Ave., ...... sis, University of Kentucky, Lexington, KY, USA, 1998.

288

Beam lifetime and emittance growth in RHIC under normal operating conditions with the hydrogen gas jet, the cluster-jet and pellet targets  

DOE Green Energy (OSTI)

The inelastic scattering of the beam and the residual gas molecules in RHIC could represent one of the limitations on the beam life time and emittance growth. This report covers the dominant central nuclear collisions influence on the beam lifetime and transverse emittance growth. The cross sections for the beam-gas electron radiative captures are an order of magnitude smaller. The capture cross sections include the radiative and non-radiative capture, and the capture from the electron-positron pair creation from the 'vacuum capture'.

Trbojevic, D.

2010-09-01T23:59:59.000Z

289

Measurement of the t anti-t production cross-section at s**(1/2) = 1.96-TeV using lifetime tagging  

SciTech Connect

A measurement of the t{bar t} production cross section in the lepton+jets channels with the D0 detector at {radical}s = 1.96 TeV using the lifetime-tagging techniques is presented. The t{bar t} cross section is estimated from the combination of the e+jets and {mu}+jets channels. The obtained result {sigma}{sub t{bar t}} = 7.47{sub -1.14}{sup +1.22}(stat){sub -1.03}{sup +1.65}(syst) {+-} 0.49(lumi) pb is consistent with the Standard Model expectation.

Khanov, Alexander; /Rochester U.

2004-07-01T23:59:59.000Z

290

The Effect of a Contrast Agent on Proton Beam Range in Radiotherapy Planning Using Computed Tomography for Patients With Locoregionally Advanced Lung Cancer  

SciTech Connect

Purpose: We evaluated the effect of a contrast agent (CA) on proton beam range in a treatment planning system (TPS) for patients with locoregionally advanced lung cancer. Methods and Materials: Two sets of computed tomography (CT) images (with and without CA) were obtained from 20 patients with lung cancer. Because the increase in Hounsfield unit ( Increment HU) value of the heart and great vessels due to the effect of CA is most prominent among thoracic structures, to evaluate the effect of CA on proton beam range in the TPS, we compared the calculated distal ranges in the plan with CA-enhanced CT with those with corrected CT, in which the HU values of the heart and great vessels in the CA-enhanced CT were replaced by average HU values obtained from the unenhanced CT. Results: The mean Increment HU value and the longest length of the heart and great vessels within the proton beam path in the field that passed through these structures were 189 {+-} 29 HU (range, 110-250 HU) and 7.1 {+-} 1.1 cm (range, 2.6-11.2 cm), respectively. The mean distal range error in the TPS because of the presence of CA was 1.0 {+-} 0.7 cm (range, 0.2-2.6 cm). Conclusion: If CA-enhanced CT images are used for radiotherapy planning using a proton beam for the treatment of lung cancer, our results suggest that the HU values of the heart and great vessels should be replaced by the average HU values of soft tissue to avoid discrepancies between planned and delivered doses.

Hwang, Ui-Jung; Shin, Dong Ho [Proton Therapy Center, Research Institute and Hospital, National Cancer Center, Goyang, Gyeonggi (Korea, Republic of); Kim, Tae Hyun, E-mail: k2onco@naver.com [Proton Therapy Center, Research Institute and Hospital, National Cancer Center, Goyang, Gyeonggi (Korea, Republic of); Moon, Sung Ho; Lim, Young Kyung; Jeong, Hojin; Rah, Jeong-Eun; Kim, Sang Soo; Kim, Joo-Young; Kim, Dae Yong; Park, Sung Yong; Cho, Kwan Ho [Proton Therapy Center, Research Institute and Hospital, National Cancer Center, Goyang, Gyeonggi (Korea, Republic of)

2011-11-15T23:59:59.000Z

291

Measurement of the $\\Lambda_b^0$ lifetime in the exclusive decay $\\Lambda_b^0 \\to J/\\psi \\Lambda^0$ in $p\\bar{p}$ collisions at $\\sqrt{s}=1.96$ TeV  

Science Conference Proceedings (OSTI)

We measure the {Lambda}{sub b}{sup 0} lifetime in the fully reconstructed decay {Lambda}{sub b}{sup 0} {yields} J/{psi} {Lambda}{sup 0} using 10.4 fb{sup -1} of p{bar p} collisions collected with the D0 detector at {radical}s = 1.96 TeV. The lifetime of the topologically similar decay channel B{sup 0} {yields} J/{psi} K{sub S}{sup 0} is also measured. We obtain {tau} ({Lambda}{sub b}{sup 0}) = 1.303 {+-} 0.075 (stat.) {+-} 0.035 (syst.) ps and {tau} (B{sup 0}) = 1.508 {+-} 0.025 (stat.) {+-} 0.043 (syst.) ps. Using these measurements, we determine the lifetime ratio of {tau} ({Lambda}{sub b}{sup 0})/{tau} (B{sup 0}) = 0.864 {+-} 0.052 (stat.) {+-} 0.033 (syst.).

Abazov, Victor Mukhamedovich; Abbott, Braden Keim; Acharya, Bannanje Sripath; Adams, Mark Raymond; Adams, Todd; Alexeev, Guennadi D.; Alkhazov, Georgiy D.; Alton, Andrew K.; Alverson, George O.; Aoki, Masato; Askew, Andrew Warren; /Rio de Janeiro, CBPF /Rio de Janeiro State U. /ABC Federal U. /Hefei, CUST /Andes U., Bogota /Charles U. /Prague, Tech. U. /Prague, Inst. Phys. /San Francisco de Quito U. /Clermont-Ferrand U. /LPSC, Grenoble

2012-04-01T23:59:59.000Z

292

Aging Impacts Transcriptome but not Genome of Hormone-dependent Breast Cancers  

E-Print Network (OSTI)

and Cancer Interface. Cancer Research 2007, Geigl JB, LangerBreast Cancer Research This Provisional PDF corresponds tobreast cancers Breast Cancer Research 2007, 9:R59 doi:

2007-01-01T23:59:59.000Z

293

Accelerators for Cancer Therapy  

DOE R&D Accomplishments (OSTI)

The vast majority of radiation treatments for cancerous tumors are given using electron linacs that provide both electrons and photons at several energies. Design and construction of these linacs are based on mature technology that is rapidly becoming more and more standardized and sophisticated. The use of hadrons such as neutrons, protons, alphas, or carbon, oxygen and neon ions is relatively new. Accelerators for hadron therapy are far from standardized, but the use of hadron therapy as an alternative to conventional radiation has led to significant improvements and refinements in conventional treatment techniques. This paper presents the rationale for radiation therapy, describes the accelerators used in conventional and hadron therapy, and outlines the issues that must still be resolved in the emerging field of hadron therapy.

Lennox, Arlene J.

2000-05-30T23:59:59.000Z

294

Radiosensitization of Human Cervical Cancer Cells by Inhibiting Ribonucleotide Reductase: Enhanced Radiation Response at Low-Dose Rates  

Science Conference Proceedings (OSTI)

Purpose: To test whether pharmacologic inhibition of ribonucleotide reductase (RNR) by 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP, NSC no. 663249) enhances radiation sensitivity during low-dose-rate ionizing radiation provided by a novel purpose-built iridium-192 cell irradiator. Methods and Materials: The cells were exposed to low-dose-rate radiation (11, 23, 37, 67 cGy/h) using a custom-fabricated cell irradiator or to high-dose-rate radiation (330 cGy/min) using a conventional cell irradiator. The radiation sensitivity of human cervical (CaSki, C33-a) cancer cells with or without RNR inhibition by 3-AP was evaluated using a clonogenic survival and an RNR activity assay. Alteration in the cell cycle distribution was monitored using flow cytometry. Results: Increasing radiation sensitivity of both CaSki and C33-a cells was observed with the incremental increase in radiation dose rates. 3-AP treatment led to enhanced radiation sensitivity in both cell lines, eliminating differences in cell cytotoxicity from the radiation dose rate. RNR blockade by 3-AP during low-dose-rate irradiation was associated with low RNR activity and extended G{sub 1}-phase cell cycle arrest. Conclusions: We conclude that RNR inhibition by 3-AP impedes DNA damage repair mechanisms that rely on deoxyribonucleotide production and thereby increases radiation sensitivity of human cervical cancers to low-dose-rate radiation.

Kunos, Charles A., E-mail: charles.kunos@UHhospitals.org [Department of Radiation Oncology, University Hospitals Case Medical Center and Case Western Reserve School of Medicine, Cleveland, OH (United States); Colussi, Valdir C. [Department of Radiation Oncology, University Hospitals Case Medical Center and Case Western Reserve School of Medicine, Cleveland, OH (United States); Pink, John [Department of General Medical Sciences, University Hospitals Case Medical Center and Case Western Reserve School of Medicine, Cleveland, OH (United States); Radivoyevitch, Tomas [Department of Epidemiology and Biostatistics, Case Comprehensive Cancer Center, University Hospitals Case Medical Center and Case Western Reserve School of Medicine, Cleveland, OH (United States); Oleinick, Nancy L. [Department of Radiation Oncology, University Hospitals Case Medical Center and Case Western Reserve School of Medicine, Cleveland, OH (United States)

2011-07-15T23:59:59.000Z

295

Fertility, pregnancy, and breastfeeding among younger breast cancer survivors  

E-Print Network (OSTI)

the California Breast Cancer Research Program, who awardedthe California Breast Cancer Research Program, dissertationquality of life. Breast cancer Research and Treatment. 1996;

Gorman, Jessica Lynn Rickard

2009-01-01T23:59:59.000Z

296

Physics and Cancer Student Homepage  

NLE Websites -- All DOE Office Websites (Extended Search)

tests. He had an MRI that showed a growth in the area of swelling around his salivary gland and, after a biopsy, was diagnosed with salivary gland cancer and has been recommended...

297

Steps to Preventing Colon Cancer  

NLE Websites -- All DOE Office Websites (Extended Search)

watch out for belly fat. One of the key findings from the CUP report is that excess body fat is linked to increased risk of colorectal cancer. The report also concludes that...

298

EPS Global International Cancer Conference  

NLE Websites -- All DOE Office Websites (Extended Search)

Sept.10-12th, 2010 Suzhou, China Welcome Message Dear Colleagues and Friends, It is my pleasure to announce that EPS Global International Cancer Conference will be held on...

299

Identifying and Understanding the Functional Significance of Cancer Stem Cells in Prostate and Pancreatic Cancer Initiation and Chemoresistance  

E-Print Network (OSTI)

prostate tumorigenesis. Cancer Research, 71: 3459-3470. Kongprogenitor cells. Cancer Research, 72: 1878-89. Murtaughin human brain tumors. Cancer Research, 63: 5821-5828. Steer

Hindoyan, Antreas Agop

2013-01-01T23:59:59.000Z

300

Study of familial breast cancer: identifying additional breast cancer susceptibility loci;.  

E-Print Network (OSTI)

??Breast cancer is a serious public health concern and despite intensive research, the etiology of breast cancer is poorly understood. Known risk factors explain only… (more)

Allen-Brady, Kristina Lisa

2006-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "incremental lifetime cancer" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


301

Chapter 27 -- Breast Cancer Genomics, Section VI, Pathology and Biological Markers of Invasive Breast Cancer  

E-Print Network (OSTI)

11.  Katoh M.  Cancer genomics and genetics of FGFR2 [Chapter 27  Breast Cancer Genomics  Paul T.  Spellman, 

Spellman, Paul T.

2011-01-01T23:59:59.000Z

302

Microchip Technology for High-Throughput Cancer Pathology  

E-Print Network (OSTI)

Sequencing in Cancer Research . . . . 80 Appendix A: High-the Warburg Effect. Cancer Research, 2006. 66(18): p. 8927-Breast Cancer Risk. Cancer Research, 2007. 67(10): p. 4687-

Duberow, Jr, David Paul

2009-01-01T23:59:59.000Z

303

Relativistic many-body calculation of energies, oscillator strengths, transition rates, lifetimes, polarizabilities, and quadrupole moment of Fr-like Th IV ion  

E-Print Network (OSTI)

Atomic properties of the 24 low-lying ns, np, nd, nf, and ng states in Th IV ion are calculated using the high-precision relativistic all-order method where all single, double, and partial triple excitations of the Dirac-Fock wave functions are included to all orders of perturbation theory. Recommended values are provided for a large number of electric-dipole matrix elements, oscillator strengths, transition rates, and lifetimes. Scalar polarizabilities of the ground and six excited states (5f_j, 6d_j, 7p_j, and 7s), and tensor polarizabilities of the 5f_j, 6d_j, 7p_{3/2} states of Th IV are evaluated. The uncertainties of the recommended values are estimated. These calculations provide recommended values critically evaluated for their accuracy for a number of Th IV atomic properties for use in theoretical modeling as well as planning and analysis of various experiments including development of ultra precise nuclear clock and RESIS studies of actinide ions

M. S. Safronova; U. I. Safronova

2013-03-31T23:59:59.000Z

304

Relativistic many-body calculation of energies, oscillator strengths, transition rates, lifetimes, polarizabilities, and quadrupole moment of Fr-like Th IV ion  

E-Print Network (OSTI)

Atomic properties of the 24 low-lying ns, np, nd, nf, and ng states in Th IV ion are calculated using the high-precision relativistic all-order method where all single, double, and partial triple excitations of the Dirac-Fock wave functions are included to all orders of perturbation theory. Recommended values are provided for a large number of electric-dipole matrix elements, oscillator strengths, transition rates, and lifetimes. Scalar polarizabilities of the ground and six excited states (5f_j, 6d_j, 7p_j, and 7s), and tensor polarizabilities of the 5f_j, 6d_j, 7p_{3/2} states of Th IV are evaluated. The uncertainties of the recommended values are estimated. These calculations provide recommended values critically evaluated for their accuracy for a number of Th IV atomic properties for use in theoretical modeling as well as planning and analysis of various experiments including development of ultra precise nuclear clock and RESIS studies of actinide ions

Safronova, M S

2013-01-01T23:59:59.000Z

305

Analysis of Senate Bill 1245: Cervical Cancer Screening Test  

E-Print Network (OSTI)

cervical cancer mortality by race/ethnicity Other researchCancer: Recommendations and Rationale. Rockville, MD: Agency for Healthcare Research

California Health Benefits Review Program (CHBRP)

2006-01-01T23:59:59.000Z

306

Genetics and molecular biology of breast cancer  

SciTech Connect

This volume contains the abstracts of oral presentations and poster sessions presented at the Cold Springs Harbor Meeting on Cancer Cells, this meeting entitled Genetics and Molecular Biology of Breast Cancer.

King, M.C. [California Univ., Berkeley, CA (United States); Lippman, M. [Georgetown Univ. Medical Center, Washington, DC (United States)] [comps.

1992-12-31T23:59:59.000Z

307

Targeting cancer metabolism: a therapeutic window opens  

E-Print Network (OSTI)

Genetic events in cancer activate signalling pathways that alter cell metabolism. Clinical evidence has linked cell metabolism with cancer outcomes. Together, these observations have raised interest in targeting metabolic ...

Vander Heiden, Matthew G.

308

Magnetically Trapped Neutron Lifetime Experiment  

Science Conference Proceedings (OSTI)

... the theory of Big Bang Nucleosynthesis. As well as in determinations of the expected neutrino flux from nuclear reactors. ...

2013-07-22T23:59:59.000Z

309

lifetime members Abbott Laboratories Fund  

E-Print Network (OSTI)

Beth Israel John R. and Annie W. Furrer John M. and Joan F. Perrigo J. Spencer Standish John Carney, Jr Tyson William F. Whitman, Jr. and Barbara Whitman Katharine Wilson Clay and Camille Yates Bernard S. and Susan S. Cohon Bernard S. and Sarah M. Gewirz Barbara B. Salem Marie C. Stiefel Camp-Younts Foundation

Peterson, Blake R.

310

HWVP melter lifetime prediction letter  

SciTech Connect

Preliminary predictions were made of the time to reach hypothesized operational limits of the HWVP melter due to build up of a noble metals sludge layer on the melter floor. Predictions were made with the TEMPEST computer program, Version T2.9h, for use in the MPA activity in the Pacific Northwest Laboratory`s (PNL) Hanford Waste Vitrification Plant (HWVP) Technology Development (PHTD) effort. The NWEST computer program (Trent and Eyler 1993) is a PNL-MA-70/Part 2 -- Good Practices Standard (QA Level III) research and development software tool.

Eyler, L.L.; Mahoney, L.A.; Elliott, M.L.

1996-03-01T23:59:59.000Z

311

Relativistic many-body calculations of lifetimes, rates, and line strengths of multipole transitions between 3l-1 4l' states in Ni-like ions  

Science Conference Proceedings (OSTI)

Transition rates and line strengths are calculated for electric-multipole (E2 and E3) and magnetic-multipole (M1, M2, and M3) transitions between 3s{sup 2}3p{sup 6}3d{sup 10}, 3s{sup 2}3p{sup 6}3d{sup 9}4l, 3s{sup 2}3p{sup 5}3d{sup 10}4l, and 3s3p{sup 6}3d{sup 10}4l states (with 4l = 4s, 4p, 4d, and 4f) in Ni-like ions with the nuclear charges ranging from Z = 34 to 100. Relativistic many-body perturbation theory (RMBPT), including the Breit interaction, is used to evaluate retarded multipole matrix elements. Transition energies used in the calculation of line strengths and transition rates are from second-order RMBPT. Lifetimes of the 3s{sup 2}3p{sup 6}3d{sup 9}4s levels are given for Z = 34-100. Taking into account that calculations were performed in a very broad range of Z, most of the data are presented in graphs as Z-dependencies. The full set of data is given only for Ni-like W ion. In addition, we also give complete results for the 3d4s{sup 3}D{sub 2}-3d4s {sup 3}D{sub 1} magnetic-dipole transition, as the transition may be observed in future experiments, which measure both transition energies and radiative rates. These atomic data are important in the modeling of radiation spectra from Ni-like multiply-charged ions generated in electron beam ion trap experiments as well as for laboratory plasma diagnostics including fusion research.

Safronova, U I; Safronova, A S; Beiersdorfer, P

2007-10-08T23:59:59.000Z

312

Measurement of D0-D0bar Mixing using the Ratio of D0->K-pi and K-K Lifetimes  

SciTech Connect

We measure the rate of D{sup 0}-{bar D}{sup 0} mixing with the observable y{sub CP} = ({tau}{sub K{pi}}/{tau}{sub KK}) - 1, where {tau}{sub KK} and {tau}{sub K{pi}} are respectively the mean lifetimes of CP-even D{sup 0} {yields} K{sup +}K{sup -} and CP-mixed D{sup 0} {yields} K{sup -}{pi}{sup +} decays, using a data sample of 384 fb{sup -1} collected by the BABAR detector at the SLAC PEP-II asymmetric-energy B Factory. From a sample of D{sup 0} and {bar D}{sup 0} decays where the initial flavor of the decaying meson is not determined, we obtain y{sub CP} = [1.12 {+-} 0.26(stat) {+-} 0.22(syst)]%, which excludes the no-mixing hypothesis at 3.3{sigma}, including both statistical and systematic uncertainties. This result is in good agreement with a previous BABAR measurement of y{sub CP} obtained from a sample of D*{sup +} {yields} D{sup 0}{pi}{sup +} events, where the D{sup 0} decays to K{sup -}{pi}{sup +}, K{sup +}K{sup -}, and {pi}{sup +}{pi}{sup -}, which is disjoint with the untagged D{sup 0} events used here. Combining the two results taking into account statistical and systematic uncertainties, where the systematic uncertainties are assumed to be 100% correlated, we find y{sub CP} = [1.16 {+-} 0.22(stat) {+-} 0.18(syst)]%, which excludes the no-mixing hypothesis at 4.1{sigma}.

Aubert, B.; Karyotakis, Y.; Lees, J.P.; Poireau, V.; Prencipe, E.; Prudent, X.; Tisserand, V.; /Annecy, LAPP; Tico, J.Garra; Grauges, E.; /Barcelona U.; Martinelli, M.; Palano, A.; Pappagallo, M.; /INFN, Bari /Bari U.; Eigen, G.; Stugu, B.; Sun, L.; /Bergen U.; Battaglia, M.; Brown, D.N.; Hooberman, B.; Kerth, L.T.; Kolomensky, Yu.G.; Lynch, G.; /UC, Berkeley /Birmingham U. /Ruhr U., Bochum /British Columbia U. /Brunel U. /Novosibirsk, IYF /UC, Irvine /UC, Riverside /UC, San Diego /UC, Santa Barbara /UC, Santa Cruz /Caltech /Cincinnati U. /Colorado U. /Colorado State U. /Dortmund U. /Dresden, Tech. U. /Ecole Polytechnique /Edinburgh U. /INFN, Ferrara /Ferrara U. /INFN, Ferrara /INFN, Ferrara /Ferrara U. /INFN, Ferrara /INFN, Ferrara /Ferrara U. /Frascati /INFN, Genoa /Genoa U. /INFN, Genoa /INFN, Genoa /Genoa U. /INFN, Genoa /INFN, Genoa /Genoa U. /INFN, Genoa /INFN, Genoa /Genoa U. /Harvard U. /Heidelberg U. /Humboldt State U. /Imperial Coll., London /Iowa State U. /Iowa State U. /Johns Hopkins U. /Orsay, LAL /LLNL, Livermore /Liverpool U. /Queen Mary, U. of London /Royal Holloway, U. of London /Royal Holloway, U. of London /Louisville U. /Mainz U., Inst. Kernphys. /Manchester U. /Maryland U. /Massachusetts U., Amherst /MIT /McGill U. /INFN, Milan /Milan U. /INFN, Milan /INFN, Milan /Milan U. /Mississippi U. /Montreal U. /Mt. Holyoke Coll. /INFN, Naples /Naples U. /INFN, Naples /INFN, Naples /Naples U. /NIKHEF, Amsterdam /NIKHEF, Amsterdam /Notre Dame U. /Ohio State U. /Oregon U. /INFN, Padua /Padua U. /INFN, Padua /INFN, Padua /Padua U. /Paris U., VI-VII /Pennsylvania U. /INFN, Perugia /Perugia U. /INFN, Pisa /Pisa U. /INFN, Pisa /Pisa, Scuola Normale Superiore /INFN, Pisa /Pisa U. /INFN, Pisa /Princeton U. /INFN, Rome /INFN, Rome /Rome U. /INFN, Rome /INFN, Rome /Rome U. /INFN, Rome /INFN, Rome /Rome U. /INFN, Rome /INFN, Rome /Rome U. /INFN, Rome /Rostock U. /Rutherford /DAPNIA, Saclay /SLAC /South Carolina U. /Stanford U., Phys. Dept. /SUNY, Albany /Tel Aviv U. /Tennessee U. /Texas U. /Texas U., Dallas /INFN, Turin /Turin U. /INFN, Trieste /Trieste U. /Valencia U. /Victoria U. /Warwick U. /Wisconsin U., Madison

2009-10-17T23:59:59.000Z

313

Differential expression of anterior gradient gene AGR2 in prostate cancer  

E-Print Network (OSTI)

circulating tumor cells. Cancer research 2005, 48. Kovalev2 in prostate cancer. Cancer research 2010, 19. Zhang Y,cellular transformation. Cancer research 2008, 68(2):492-

2010-01-01T23:59:59.000Z

314

Predictive and therapeutic markers in ovarian cancer  

DOE Patents (OSTI)

Cancer markers may be developed to detect diseases characterized by increased expression of apoptosis-suppressing genes, such as aggressive cancers. Genes in the human chromosomal regions, 8q24, 11q13, 20q11-q13, were found to be amplified indicating in vivo drug resistance in diseases such as ovarian cancer. Diagnosis and assessment of amplification levels certain genes shown to be amplified, including PVT1, can be useful in prediction of poor outcome of patient's response and drug resistance in ovarian cancer patients with low survival rates. Certain genes were found to be high priority therapeutic targets by the identification of recurrent aberrations involving genome sequence, copy number and/or gene expression are associated with reduced survival duration in certain diseases and cancers, specifically ovarian cancer. Therapeutics to inhibit amplification and inhibitors of one of these genes, PVT1, target drug resistance in ovarian cancer patients with low survival rates is described.

Gray, Joe W.; Guan, Yinghui; Kuo, Wen-Lin; Fridlyand, Jane; Mills, Gordon B.

2013-03-26T23:59:59.000Z

315

Cancer in atomic bomb survivors  

SciTech Connect

Radiation carcinogenesis was first noted in studies of individuals with occupational or therapeutic exposure to radiation. Data from long-term follow-up studies of atomic bomb survivors in Hiroshima and Nagasaki have greatly enhanced our knowledge of radiation carcinogenesis. This book presents current results obtained from epidemiological studies and pathological studies on cancer among atomic bomb survivors. It includes a description of the dosimetry system which is currently being revised. Although many of the details about radiation carcinogenesis remain unknown or uncertain, it is clear that the incidence of radiation-induced cancer among atomic bomb survivors continues unabated 40 years after exposure. Recent increases in occupational and environmental exposure to radiation together with the need for a thorough review of radiation protection standards have led to increased recognition of the importance of research on radiation carcinogenesis and risk assessment.

Shigematsu, I.; Kagan, A.

1986-01-01T23:59:59.000Z

316

Air pollution and lung cancer  

SciTech Connect

Epidemiological evidence proves conclusively that lung cancer correlates with air pollution. However, data on lung cancer death rates and smoking show that mankind accepts the risk of long-term and low-level exposure to carcinogens. As a rule, immediate benefits are sought and remote hazards ignored. Fear of atmospheric contamination by radioactive fallout seems to be the main factor for awareness of air pollution. Experimental works help us to understand physics of particle deposition in the lungs (inertial impactation, sedimentation, Brownian movement), shed light on carcinogenesis (eg, bay region theory in case of polycyclic aromatic hydrocarbons and surface charge changes regarding asbestos), show that atmospheric particulates accepted as harmless may act as co-carcinogens (eg, iron and benzo(a)pyrene) and stress the importance of in vitro research (bacterial mutation tests, organ cultures, sister chromatid exchange system) to screen pollutants for their malignant potential and study their pathogenesis.

Boehm, G.M.

1982-01-01T23:59:59.000Z

317

Available Technologies: High Selectivity Peptides for Cancer ...  

Biofuels; Biotechnology & Medicine. Diagnostics and Therapeutics; Medical Devices; ... Rac1b: A Highly Selective Marker and Target for Cancer, IB-2167 ;

318

Laser research shows promise for cancer treatment  

NLE Websites -- All DOE Office Websites (Extended Search)

treatment Laser research shows promise for cancer treatment Scientists have observed for the first time how a laser penetrates dense, electron-rich plasma to generate ions. August...

319

HIV/Cancer DB Match Document  

NLE Websites -- All DOE Office Websites (Extended Search)

Los Angeles Massachusetts New York New Jersey San Diego San Francisco Seattle METHODS Matching The Cancer and HIVAIDS records were linked using the commercially...

320

BMC Cancer BioMed Central  

E-Print Network (OSTI)

Research article Genistein inhibits radiation-induced activation of NF-?B in prostate cancer cells promoting apoptosis and G2 /M cell cycle arrest

Julian J Raffoul; Yu Wang; Omer Kucuk; Jeffrey D Forman; Fazlul H Sarkar; Gilda G Hillman; Jeffrey D Forman; Fazlul H Sarkar; Gilda G Hillman

2006-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "incremental lifetime cancer" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


321

Improving Screening Strategies for Prostate Cancer.  

E-Print Network (OSTI)

??Th is thesis describes research on screening for prostate cancer. To improve understanding of the thesis, some background information will be provided in this introduction.… (more)

Wolters, T.

2010-01-01T23:59:59.000Z

322

Aligned Nanofiber Multiwell Plates for Cancer Research  

Science Conference Proceedings (OSTI)

Presentation Title, Aligned Nanofiber Multiwell Plates for Cancer Research. Author(s), John Lannutti, Jed Johnson. On-Site Speaker (Planned), John Lannutti

323

Boron Nanotechnology-driven Cancer Therapy  

Science Conference Proceedings (OSTI)

Presentation Title, Boron Nanotechnology-driven Cancer Therapy ... Current research focuses on both the design and synthesis of high boron containing ...

324

Molecular Epidemiology of Human Cancer Risk  

Science Conference Proceedings (OSTI)

Epidemiology has identified several etiological factors in lung cancer, of which the most ... Finally, most molecular epidemiology studies include genetic research.

325

Molecular Cancer BioMed Central  

E-Print Network (OSTI)

A doxycycline-inducible urokinase receptor (uPAR) upregulates uPAR activities including resistance to anoikis in human prostate cancer cell lines

Mohammad Hasanuzzaman; Robert Kutner; Siamak Agha-mohammadi; Jakob Reiser; Inder Sehgal

2007-01-01T23:59:59.000Z

326

Biocompatible Nanoparticle Materials in Cancer Research  

Science Conference Proceedings (OSTI)

The challenges and future perspectives of nanomedicine in cancer research will .... Self-Adaptive, Ultra-Compliant Shape Memory Alloys for Medical Implant ...

327

BMC Cancer BioMed Central  

E-Print Network (OSTI)

Research article Polymorphisms in thymidylate synthase gene and susceptibility to breast cancer in a Chinese population: a case-control analysis

Xiangjun Zhai; Jun Gao; Zhibin Hu; Jinhai Tang; Jianwei Qin; Shui Wang; Xuechen Wang; Guangfu Jin; Jiyong Liu; Wenshen Chen; Feng Chen; Xinru Wang; Qingyi Wei; Hongbing Shen; Qingyi Wei; Hongbing Shen

2006-01-01T23:59:59.000Z

328

Nanomaterials for the detection of cancer-associated biomarkers  

E-Print Network (OSTI)

Prostate cancer persists as a major public health issue in the United States and remains the second leading cause of cancer death in men. Early detection and disease monitoring in prostate cancer can significantly improve ...

Mu, Chunyao Jenny

2010-01-01T23:59:59.000Z

329

Perspectives on the mesenchymal origin of metastatic cancer  

E-Print Network (OSTI)

microenvironments. Cancer Research, 39. Pollard, J. W. (host × tumor hybrids. Cancer Research, 60(9), 2512–2519. 98.program. Clinical Cancer Research, 14(12), 3643–3645. 17.

Huysentruyt, Leanne C.; Seyfried, Thomas N.

2010-01-01T23:59:59.000Z

330

An MRI compatible manipulator for prostate cancer detection and treatment  

E-Print Network (OSTI)

Prostate cancer is the most frequently diagnosed cancer in men and the second most common cause of cancer related death in men. Prostate specific antigen (PSA) blood tests and digital rectal exams (DRE) are preliminary ...

DeVita, Lauren M

2007-01-01T23:59:59.000Z

331

Isotope production facility produces cancer-fighting actinium  

NLE Websites -- All DOE Office Websites (Extended Search)

Cancer therapy gets a boost from new isotope Isotope production facility produces cancer-fighting actinium A new medical isotope project shows promise for rapidly producing major...

332

EA-0965: Cancer Research Center Indiana University School of...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

5: Cancer Research Center Indiana University School of Medicine, Argonne, Illinois EA-0965: Cancer Research Center Indiana University School of Medicine, Argonne, Illinois SUMMARY...

333

Endoscopic Electron-Beam Cancer Therapy | Argonne National Laboratory  

NLE Websites -- All DOE Office Websites (Extended Search)

Endoscopic Electron-Beam Cancer Therapy Technology available for licensing: A successful and cost-effective means of treating cancer in previously inoperable or radiation-sensitive...

334

Development of Biomarker-based Systems for Cancer ...  

Science Conference Proceedings (OSTI)

... in the US. The cancer community has set a goal to eliminate cancer-related suffering and death by 2015. To achieve this ...

2013-07-23T23:59:59.000Z

335

ORIGINAL RESEARCH Health Behaviors and Quality of Life of Cancer Survivors in Massachusetts, 2006: Data Use for Comprehensive Cancer Control  

E-Print Network (OSTI)

Pierre S. Health behaviors and quality of life of cancer survivors in Massachusetts, 2006: data use for comprehensive cancer control. Prev Chronic Dis 2010;7(1).

Temeika L. Fairley; Phd Helen Hawk; Phd Snaltze Pierre; Peer Reviewed

2010-01-01T23:59:59.000Z

336

A Geographic Information System (GIS) Analysis of Cancer Clinical Trial Locations in the State of Georgia by Major Cancer Type.  

E-Print Network (OSTI)

??Improving cancer care through clinical research is a major public health issue. However, in Georgia, the exact number of cancer clinical trials is unknown, indicating… (more)

Parker, Shaunta Shanell

2008-01-01T23:59:59.000Z

337

Restoration of normal phenotype in cancer cells  

DOE Patents (OSTI)

A method for reversing expression of malignant phenotype in cancer cells is described. The method comprises applying .beta..sub.1 integrin function-blocking antibody to the cells. The method can be used to assess the progress of cancer therapy. Human breast epithelial cells were shown to be particularly responsive.

Bissell, Mina J. (Berkeley, CA); Weaver, Valerie M. (Oakland, CA)

1998-01-01T23:59:59.000Z

338

Restoration of normal phenotype in cancer cells  

DOE Patents (OSTI)

A method for reversing expression of malignant phenotype in cancer cells is described. The method comprises applying {beta}{sub 1} integrin function-blocking antibody to the cells. The method can be used to assess the progress of cancer therapy. Human breast epithelial cells were shown to be particularly responsive. 14 figs.

Bissell, M.J.; Weaver, V.M.

1998-12-08T23:59:59.000Z

339

Prediction of Breast Cancer Using Artificial Neural Networks  

Science Conference Proceedings (OSTI)

In this study, an artificial neural network (ANN) was developed to determine whether patients have breast cancer or not. Whether patients have cancer or not and if they have its type can be determined by using ANN and BI-RADS evaluation and based on ... Keywords: Artificial neural network, BI-RADS, Breast cancer, Breast cancer prediction

Ismail Saritas

2012-10-01T23:59:59.000Z

340

Manipulating electron beam cancer therapy so it can be used treat internal cancers and tumors has the potential to  

E-Print Network (OSTI)

exposure provides several new cancer therapies or treatments in previously inoperable or radiationManipulating electron beam cancer therapy so it can be used treat internal cancers and tumors has-effective means of treating cancer in previously inoperable or radiation-sensitive areas of the body. Technology

Kemner, Ken

Note: This page contains sample records for the topic "incremental lifetime cancer" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


341

Characterization of an engineered human purine nucleoside phosphorylase fused to an anti-her2/neu single chain Fv for use in ADEPT  

E-Print Network (OSTI)

lifetime." Sir Paul Nurse, Cancer Research UK Your researchof Experimental & Clinical Cancer Research Research BioMedof Experimental & Clinical Cancer Research 2009, 28:147 doi:

Afshar, Sepideh; Olafsen, Tove; Wu, Anna M; Morrison, Sherie L

2009-01-01T23:59:59.000Z

342

Cancer incidence in atomic bomb survivors. Part IV: Comparison of cancer incidence and mortality  

SciTech Connect

This report compares cancer incidence and mortality among atomic bomb survivors in the Radiation Effects Research Foundation Life Span Study (LSS) cohort. Because the incidence data are derived from the Hiroshima and Nagasaki tumor registries, case ascertainment is limited to the time (1958-1987) and geographic restrictions (Hiroshima and Nagasaki) of the registries, whereas mortality data are available from 1950-1987 anywhere in Japan. With these conditions, there were 9,014 first primary incident cancer cases identified among LSS cohort members compared with 7,308 deaths for which cancer was listed as the underlying cause of death on death certificates. When deaths were limited to those occurring between 1958-1987 in Hiroshima or Nagasaki, there were 3,155 more incident cancer cases overall, and 1,262 more cancers of the digestive system. For cancers of the oral cavity and pharynx, skin, breast, female and male genital organs, urinary system and thyroid, the incidence series was at least twice as large as the comparable mortality series. Although the incidence and mortality data are dissimilar in many ways, the overall conclusions regarding which solid cancers provide evidence of a significant dose response generally confirm the mortality findings. When either incidence or mortality data are evaluated, significant excess risks are observed for all solid cancers, stomach, colon, liver (when it is defined as primary liver cancer or liver cancer not otherwise specified on the death certificate), lung, breast, ovary and urinary bladder. No significant radiation effect is seen for cancers of the pharynx, rectum, gallbladder, pancreas, nose, larynx, uterus, prostate or kidney in either series. There is evidence of a significant excess of nonmelanoma skin cancer in the incidence data, but not in the mortality series. 19 refs., 2 figs., 10 tabs.

Ron, E. (Radiation Effects Research Foundation, Hiroshima (Japan) National Cancer Institute, Bethesda, MD (United States)); Preston, D.L.; Mabuchi, Kiyohiko (Radiation Effects Research Foundation, Hiroshima (Japan)); Thompson, D.E. (Radiation Effects Research Foundation, Hiroshima (Japan) George Washington Univ., Rockville, MD (United States) Radiation Effects Research Foundation, Nagasaki (Japan)); Soda, Midori (Radiation Effects Research Foundation, Nagasaki (Japan))

1994-02-01T23:59:59.000Z

343

Coping with Mom's breast cancer: impact of parental cancer on African-American adolescents.  

E-Print Network (OSTI)

??Parental breast cancer is an illness that affects the patient as well as the entire family. A review of literature shows that very limited research… (more)

Dockery, Kimberley D.

2008-01-01T23:59:59.000Z

344

Central-local transfers in Kenya - Options for incremental reform  

E-Print Network (OSTI)

Government Printer. Kenya, Republic of (1996) EconomicGovernment Printer. Kenya, Republic of (1995) StatisticalNairobi: Government Printer. Kenya, Republic of (1994) Kenya

Crane, Randall

2004-01-01T23:59:59.000Z

345

ADWICE – anomaly detection with real-time incremental clustering  

Science Conference Proceedings (OSTI)

Anomaly detection, detection of deviations from what is considered normal, is an important complement to misuse detection based on attack signatures. Anomaly detection in real-time places hard requirements on the algorithms used, making many proposed ... Keywords: adaptability, anomaly detection, clustering, intrusion detection, realtime

Kalle Burbeck; Simin Nadjm-Tehrani

2004-12-01T23:59:59.000Z

346

Testing Extended Regular Language Membership Incrementally by Rewriting  

E-Print Network (OSTI)

construction activities support closure of contaminated areas in compliance with the RCRA Consent Order) TRU Waste Facility (TRU) Material Disposal Area-C Closure Material Disposal Area-G Closure Waste

Rosu, Grigore

347

Incremental costs of higher efficiency can vary by appliance ...  

U.S. Energy Information Administration (EIA)

Short-Term Energy Outlook ... Search EIA.gov. A-Z Index; ... consumers can also enter cost and performance attributes of specific models they are considering.

348

Improving Incremental Balance in the GSI 3DVAR Analysis System  

Science Conference Proceedings (OSTI)

The gridpoint statistical interpolation (GSI) analysis system is a unified global/regional three-dimensional variational data assimilation (3DVAR) analysis code that has been under development for several years at the National Centers for ...

Daryl T. Kleist; David F. Parrish; John C. Derber; Russ Treadon; Ronald M. Errico; Runhua Yang

2009-03-01T23:59:59.000Z

349

Max-min separability: incremental approach and application to ...  

E-Print Network (OSTI)

?f(x) = coC, ?f(x) = coD. We denote by F the class of all semismooth, quasidifferentiable functions whose subdif- ferential and superdifferential are polytopes at ...

350

Incremental cooling load determination for passive direct gain heating systems  

DOE Green Energy (OSTI)

This paper examines the applicability of the National Association of Home Builders (NAHB) full load compressor hour method for predicting the cooling load increase in a residence, attributable to direct gain passive heating systems. The NAHB method predictions are compared with the results of 200 hour-by-hour simulations using BLAST and the two methods show reasonable agreement. The degree of agreement and the limitations of the NAHB method are discussed.

Sullivan, P.W.; Mahone, D.; Fuller, W.; Gruber, J.; Kammerud, R.; Place, W.; Andersson, B.

1981-05-01T23:59:59.000Z

351

INCREMENTAL COOLING LOAD DETERMINATION FOR PASSIVE DIRECT GAIN HEATING SYSTEMS  

E-Print Network (OSTI)

Refrigeration, and Air Conditioning Engineers Inc. , 345for Residen- tial Winter and Summer Air Conditioning,Air Conditioning Contractors of America, 1228 17th Street,

Sullivan, Paul W.

2013-01-01T23:59:59.000Z

352

Temporal order optimizations of incremental joins for composite event detection  

Science Conference Proceedings (OSTI)

Queries for composite events typically involve the four complementary dimensions of event data, event composition, relationships between events (esp. temporal and causal), and accumulating events over time windows for negation and aggregation. We consider ... Keywords: complex event processing, composite event queries, rules

François Bry; Michael Eckert

2007-06-01T23:59:59.000Z

353

Tax Increment Financing Program (TIF) (District of Columbia)  

Energy.gov (U.S. Department of Energy (DOE))

The District offers several innovative public financing tools where developers can use bond financing or bank loans to fund a portion of their construction costs. The funds are repaid over time...

354

Understanding the Impacts of Incremental Gas Supply on the Flow ...  

U.S. Energy Information Administration (EIA)

High natural gas prices and sharply higher oil and natural gas field revenues are expected to drive a resurgence in natural gas-directed drilling activity this year ...

355

An Incremental Remapping Transport Scheme on a Spherical Geodesic Grid  

Science Conference Proceedings (OSTI)

Weather and climate models contain equations for transporting conserved quantities such as the mass of air, water, ice, and associated tracers. Ideally, the numerical schemes used to solve these equations should be conservative, spatially ...

William H. Lipscomb; Todd D. Ringler

2005-08-01T23:59:59.000Z

356

Line-level incremental resynthesis techniques for FPGAs  

Science Conference Proceedings (OSTI)

FPGA logic density is roughly doubling at every process generation. Consequently, it is becoming increasingly challenging for FPGA CAD tools to keep up with the growing complexities of high-speed designs while keeping CAD run-times reasonable. In this ... Keywords: algorithms

Doris Chen; Deshanand Singh

2011-02-01T23:59:59.000Z

357

Increment in World Oil Consumption by Region, 1997-2020  

U.S. Energy Information Administration (EIA)

World oil production is projected to increase by a total of 39.8 million barrels per day ... Substantial growth is also expected in Central and South America, ...

358

Incremental cost analysis of advanced concept CAES systems  

SciTech Connect

The costs of compressed air energy storage (CAES) systems using thermal energy storage (TES) are compared to the costs of CAES systems without TES and simple cycle gas turbine systems. Comparisons are made in terms of the system energy costs levelized over the operating life of the systems. These are in 1985 price levels which is the assumed first year of operation for the systems.

Knutsen, C.A.

1979-09-01T23:59:59.000Z

359

Incremental costs of higher efficiency can vary by ...  

U.S. Energy Information Administration (EIA)

Short-Term Energy Outlook ... Search EIA.gov. A-Z Index; ... consumers can also enter cost and performance attributes of specific models they are ...

360

INCREMENTAL COOLING LOAD DETERMINATION FOR PASSIVE DIRECT GAIN HEATING SYSTEMS  

E-Print Network (OSTI)

in the publication Insulation Manual: Homes and Apartments [in Table 2 and thermal insulation values by city are givenArea) WALL AREAS Front e Insulation Area (75% of net wall

Sullivan, Paul W.

2013-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "incremental lifetime cancer" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


361

Graphical and incremental type inference: a graph transformation approach  

Science Conference Proceedings (OSTI)

We present a graph grammar based type inference system for a totally graphic development language. NiMo (Nets in Motion) can be seen as a graphic equivalent to Haskell that acts as an on-line tracer and debugger. Programs are process networks that evolve ... Keywords: graphical language, process networks, type inference, type visualization

Silvia Clerici; Cristina Zoltan; Guillermo Prestigiacomo

2010-05-01T23:59:59.000Z

362

Incremental sequential problem based training model -- Institute corporate readiness  

Science Conference Proceedings (OSTI)

The high impact of IT driven business worldwide in diversified fields has increased the need for huge quality and quantity workforce in IT corporate domain. Corporate units are hence compelled to receive/absorb incumbents from diversified educational ...

Sundaresan Iyer; S. Meenakshi; Anooja Mary Jacob

2011-05-01T23:59:59.000Z

363

Deleveraging domesticity : incremental design forays on middle income housing  

E-Print Network (OSTI)

Housing today has little do with architecture. Design is a currency of services, while housing today is intensively packaged as a consumer good. It is packaged with land as speculative real-estate, and bundled abstractly ...

Miller, Christopher M., M. Arch. (Christopher Michael). Massachusetts Institute of Technology

2013-01-01T23:59:59.000Z

364

Incremental-like Bundle Methods with Application to Energy Planning  

E-Print Network (OSTI)

are further studied from a theoretical point of view in [3]. For bundle methods, ... However, because nuclear plants can be seen as “equivalent energy reser- voirs

365

Aging Impacts Transcriptome but not Genome of Hormone-dependent Breast Cancers  

E-Print Network (OSTI)

biological basis linking aging with sporadic breast cancerTranslational Research at the Aging and Cancer Interface.Changes Associated with Aging. Cancer Res 2004, 64:8550-

2007-01-01T23:59:59.000Z

366

Combined diffuse optical tomography (DOT) and MRI system for cancer imaging in small animals  

E-Print Network (OSTI)

8, 2006 Technology in Cancer Research & Treatment, Volume 5,Technology in Cancer Research & Treatment, Volume 5, Number1161- Technology in Cancer Research & Treatment, Volume 5,

Gulsen, Gultekin; Birgul, Ozlem; Unlu, Mehmet Burcin; Shafiiha, Roshanak; Nalcioglu, Orhan

2006-01-01T23:59:59.000Z

367

Economic Impact of the California Cancer Research Act Job Creation and Economic Activity  

E-Print Network (OSTI)

of the California Cancer Research Act | 3 Several healthinitiative, the California Cancer Research Act, on the Juneeducation and breast cancer research). This analysis uses

Glantz, Stanton A.

2012-01-01T23:59:59.000Z

368

Anti-cancer actions in commonly used drugs: epidemiology led by laboratory science.  

E-Print Network (OSTI)

??Despite considerable research on cancer treatments and preventatives, poor outcomes in cancer patients are common. The vital search for effective cancer drugs often begins in… (more)

Walker, Alex J.

2011-01-01T23:59:59.000Z

369

Renal cancer-selective Englerin A induces multiple mechanisms of cell death and autophagy  

E-Print Network (OSTI)

of Experimental & Clinical Cancer Research 2013 32:57.Stem Cell & Translational Cancer Research Center, Chang GungExperimental & Clinical Cancer Research 2013, 32:57 http://

Williams, Richard T; Yu, Alice L; Diccianni, Mitchell B; Theodorakis, Emmanuel A; Batova, Ayse

2013-01-01T23:59:59.000Z

370

Defining the critical hurdles in cancer immunotherapy  

E-Print Network (OSTI)

representing Europe, Japan, China and North America to discuss collaborations to improve development, reagents, drugs and clinical protocols with potential to significantly improve cancer outcomes. Nowhere, China and North

Paris-Sud XI, Université de

371

Engineering persistent interleukin-2 for cancer immunotherapy  

E-Print Network (OSTI)

Mobilizing the immune system to recognize and destroy tumor cells is a promising strategy for treating cancer. In contrast to standard therapeutic approaches such as surgery, radiation, and chemotherapy, immunotherapy ...

Gai, Shuning

2012-01-01T23:59:59.000Z

372

Nanoparticles in cancer imaging and therapy  

Science Conference Proceedings (OSTI)

Nanoparticle contrast agents offer the potential to significantly improve existing methods of cancer diagnosis and treatment. Advantages include biocompatibility, selective accumulation in tumor cells, and reduced toxicity. Considerable research is underway ...

Leon Smith; Zdenka Kuncic; Kostya Ostrikov; Shailesh Kumar

2012-01-01T23:59:59.000Z

373

Stromal Endothelial Cells Directly Influence Cancer Progression  

E-Print Network (OSTI)

Cancer growth and metastasis are regulated in part by stromal cells such as fibroblasts and immune cells within the tumor microenvironment. Endothelial cells (ECs) are also ubiquitous within tumors because tumors are ...

Franses, Joseph Wang

374

National Melanoma/Skin Cancer Detection  

E-Print Network (OSTI)

The American Academy of Dermatology (AAD) has designated May as National Melanoma/Skin Cancer Detection and Prevention Month. In 1996, an estimated 1 million cases of skin cancer will be diagnosed, of which approximately 95 % will be squamous cell or basal cell carcinomas (1). Although the incidence of melanoma is lower than those of squamous cell and basal cell carcinomas, the case-fatality rate is highest for persons with melanoma. During 1973–1992, mortality from melanoma increased 34%—the third highest increase of all cancers (2). CDC, in collaboration with the AAD, has initiated the National Skin Cancer Prevention Education Program (NSCPEP) to increase public awareness about skin cancer and to help reduce the occurrence of and deaths associated with skin cancer. Goals of this program are to develop and disseminate educational messages for children, their parents, and other caregivers; develop guidelines for school curricula; evaluate the utility and value of the ultraviolet (UV) index; and develop educational messages for health-care providers. Additional information about this month and the NSCPEP is available from

Among Children; Young Adults

1996-01-01T23:59:59.000Z

375

Chapter 27 -- Breast Cancer Genomics, Section VI, Pathology and Biological Markers of Invasive Breast Cancer  

SciTech Connect

Breast cancer is predominantly a disease of the genome with cancers arising and progressing through accumulation of aberrations that alter the genome - by changing DNA sequence, copy number, and structure in ways that that contribute to diverse aspects of cancer pathophysiology. Classic examples of genomic events that contribute to breast cancer pathophysiology include inherited mutations in BRCA1, BRCA2, TP53, and CHK2 that contribute to the initiation of breast cancer, amplification of ERBB2 (formerly HER2) and mutations of elements of the PI3-kinase pathway that activate aspects of epidermal growth factor receptor (EGFR) signaling and deletion of CDKN2A/B that contributes to cell cycle deregulation and genome instability. It is now apparent that accumulation of these aberrations is a time-dependent process that accelerates with age. Although American women living to an age of 85 have a 1 in 8 chance of developing breast cancer, the incidence of cancer in women younger than 30 years is uncommon. This is consistent with a multistep cancer progression model whereby mutation and selection drive the tumor's development, analogous to traditional Darwinian evolution. In the case of cancer, the driving events are changes in sequence, copy number, and structure of DNA and alterations in chromatin structure or other epigenetic marks. Our understanding of the genetic, genomic, and epigenomic events that influence the development and progression of breast cancer is increasing at a remarkable rate through application of powerful analysis tools that enable genome-wide analysis of DNA sequence and structure, copy number, allelic loss, and epigenomic modification. Application of these techniques to elucidation of the nature and timing of these events is enriching our understanding of mechanisms that increase breast cancer susceptibility, enable tumor initiation and progression to metastatic disease, and determine therapeutic response or resistance. These studies also reveal the molecular differences between cancer and normal that may be exploited to therapeutic benefit or that provide targets for molecular assays that may enable early cancer detection, and predict individual disease progression or response to treatment. This chapter reviews current and future directions in genome analysis and summarizes studies that provide insights into breast cancer pathophysiology or that suggest strategies to improve breast cancer management.

Spellman, Paul T.; Heiser, Laura; Gray, Joe W.

2009-06-18T23:59:59.000Z

376

Tissue architecture and breast cancer: the role of extracellular matrix and steroid hormones  

E-Print Network (OSTI)

malignant breast. Cancer Research 59 1757–1763s; discussionfactor withdrawal. Cancer Research 56 2039–2044. Bunone G,cancer cells. Breast Cancer Research and Treatment 31 227–

Hansen, R K

2010-01-01T23:59:59.000Z

377

Polymorphisms in the stem cell pathway and esophageal cancer in a Chinese population  

E-Print Network (OSTI)

Mapping 10K Array. Cancer research, 2005. 65(7): p. 2542-American Association for Cancer Research, 1997. 8(12): p.Colorectal Cancer. Cancer Research, 2010. 70(16): p. 6629-

Wallar, Gina

2013-01-01T23:59:59.000Z

378

Early dissemination of bevacizumab for advanced colorectal cancer: a prospective cohort study  

E-Print Network (OSTI)

Cancer Institute/Cancer Research Network (grant number U01in the NCI-funded Cancer Research Network, and fifteenOutcomes: The Cancer Care Outcomes Research and Surveillance

2011-01-01T23:59:59.000Z

379

Multi-parametric numerical simulation of age-specific cancer rates in human populations  

E-Print Network (OSTI)

The CancerFit computer program allows cancer researchers to analyze epidemiologic data describing the age-specific risk of cancer in terms of hypotheses about historical environmental risks, the heritability of cancer, the ...

Kogel, John, 1981-

2004-01-01T23:59:59.000Z

380

Using decision analysis to determine the cost-effectiveness of intensity-modulated radiation therapy in the treatment of intermediate risk prostate cancer  

SciTech Connect

Background: The specific aim of this study is to evaluate the cost-effectiveness of intensity-modulated radiation therapy (IMRT) compared with three-dimensional conformal radiation therapy (3D-CRT) in the treatment of a 70-year-old with intermediate-risk prostate cancer. Methods: A Markov model was designed with the following states; posttreatment, hormone therapy, chemotherapy, and death. Transition probabilities from one state to another were calculated from rates derived from the literature for IMRT and 3D-CRT. Utility values for each health state were obtained from preliminary studies of preferences conducted at Fox Chase Cancer Center. The analysis took a payer's perspective. Expected mean costs, cost-effectiveness scatterplots, and cost acceptability curves were calculated with commercially available software. Results: The expected mean cost of patients undergoing IMRT was $47,931 with a survival of 6.27 quality-adjusted life years (QALYs). The expected mean cost of patients having 3D-CRT was $21,865 with a survival of 5.62 QALYs. The incremental cost-effectiveness comparing IMRT with CRT was $40,101/QALYs. Cost-effectiveness acceptability curve analysis revealed a 55.1% probability of IMRT being cost-effective at a $50,000/QALY willingness to pay. Conclusion: Intensity-modulated radiation therapy was found to be cost-effective, however, at the upper limits of acceptability. The results, however, are dependent on the assumptions of improved biochemical disease-free survival with fewer patients undergoing subsequent salvage therapy and improved quality of life after the treatment. In the absence of prospective randomized trials, decision analysis can help inform physicians and health policy experts on the cost-effectiveness of emerging technologies.

Konski, Andre [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States)]. E-mail: andre.konski@fccc.edu; Watkins-Bruner, Deborah [Department of Population Sciences, Fox Chase Cancer Center, Philadelphia, PA (United States); Feigenberg, Steven [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States); Hanlon, Alexandra [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States); Kulkarni, Sachin M.S. [Department of Population Sciences, Fox Chase Cancer Center, Philadelphia, PA (United States); Beck, J. Robert [Department of Information and Science Technologies, Fox Chase Cancer Center, Philadelphia, PA (United States); Horwitz, Eric M. [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States); Pollack, Alan [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States)

2006-10-01T23:59:59.000Z

Note: This page contains sample records for the topic "incremental lifetime cancer" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


381

Enzyme Structure Provides Insights into Cancer and Aging  

NLE Websites -- All DOE Office Websites (Extended Search)

Enzyme Structure Provides Insights into Cancer and Aging Enzyme Structure Provides Insights into Cancer and Aging Print Wednesday, 25 February 2009 00:00 XPD helicase is an enzyme...

382

The Antioxidant Vitamins C & EChapter 4 Vitamin C and Cancer  

Science Conference Proceedings (OSTI)

The Antioxidant Vitamins C & E Chapter 4 Vitamin C and Cancer Health Nutrition Biochemistry eChapters Health - Nutrition - Biochemistry Press Downloadable pdf of Chapter 4 Vitamin C and Cancer from ...

383

Impact of deleterious passenger mutations on cancer progression  

E-Print Network (OSTI)

Cancer progression is driven by the accumulation of a small number of genetic alterations. However, these few driver alterations reside in a cancer genome alongside tens of thousands of additional mutations termed passengers. ...

Korolev, Kirill Sergeevich

384

NATIONAL INSTITUTES OF HEALTH | National Cancer Institute LABORATORY OF PATHOLOGY  

E-Print Network (OSTI)

NATIONAL INSTITUTES OF HEALTH | National Cancer Institute LABORATORY OF PATHOLOGY National Cancer Institute (NCI) The Laboratory of Pathology, based in the NCI, provides clinical service in anatomic-scientists DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute, Center

385

Graduate Program in Cancer Cell Biology CELL SHEDDING  

E-Print Network (OSTI)

Graduate Program in Cancer Cell Biology CELL SHEDDING ANOIKIS CELL SHEDDING METASTASIS NORMAL CELLS) To the Cancer Cell Biology Program: As a Graduate Student in the Cancer Cell Biology Program, I acknowledge account of my laboratory work, commit to ethics before science and devote my full and undivided time

Mohaghegh, Shahab

386

Usability of mobile computing technologies to assist cancer patients  

Science Conference Proceedings (OSTI)

Medical researchers are constantly looking for new methods for early detection and treatment of incurable diseases. Cancer can severely hinder the lives of patients if they are not constantly attended to. Cancer patients can be assisted with the aid ... Keywords: MARKS, TinyOS, cancer, chemotherapy, mote, pervasive health care, tmote sky, wellness monitor

Rezwan Islam; Sheikh I. Ahamed; Nilothpal Talukder; Ian Obermiller

2007-11-01T23:59:59.000Z

387

Blood Vessel Normalization in the Hamster Oral Cancer Model for Experimental Cancer Therapy Studies  

Science Conference Proceedings (OSTI)

Normalization of tumor blood vessels improves drug and oxygen delivery to cancer cells. The aim of this study was to develop a technique to normalize blood vessels in the hamster cheek pouch model of oral cancer. Materials and Methods: Tumor-bearing hamsters were treated with thalidomide and were compared with controls. Results: Twenty eight hours after treatment with thalidomide, the blood vessels of premalignant tissue observable in vivo became narrower and less tortuous than those of controls; Evans Blue Dye extravasation in tumor was significantly reduced (indicating a reduction in aberrant tumor vascular hyperpermeability that compromises blood flow), and tumor blood vessel morphology in histological sections, labeled for Factor VIII, revealed a significant reduction in compressive forces. These findings indicated blood vessel normalization with a window of 48 h. Conclusion: The technique developed herein has rendered the hamster oral cancer model amenable to research, with the potential benefit of vascular normalization in head and neck cancer therapy.

Ana J. Molinari; Romina F. Aromando; Maria E. Itoiz; Marcela A. Garabalino; Andrea Monti Hughes; Elisa M. Heber; Emiliano C. C. Pozzi; David W. Nigg; Veronica A. Trivillin; Amanda E. Schwint

2012-07-01T23:59:59.000Z

388

Catalyzing social support for breast cancer patients  

Science Conference Proceedings (OSTI)

Social support is a critical, yet underutilized resource when undergoing cancer care. Underutilization occurs in two conditions: (a) when patients fail to seek out information, material assistance, and emotional support from family and friends or (b) ... Keywords: health consumers, participatory design, social network

Meredith M. Skeels; Kenton T. Unruh; Christopher Powell; Wanda Pratt

2010-04-01T23:59:59.000Z

389

Modern breast cancer detection: a technological review  

Science Conference Proceedings (OSTI)

Breast cancer is a serious threat worldwide and is the number two killer of women in the United States. The key to successful management is screening and early detection. What follows is a description of the state of the art in screening and detection ...

Adam B. Nover; Shami Jagtap; Waqas Anjum; Hakki Yegingil; Wan Y. Shih; Wei-Heng Shih; Ari D. Brooks

2009-01-01T23:59:59.000Z

390

Toward Early Diagnosis of Lung Cancer  

Science Conference Proceedings (OSTI)

Our long term research goal is to develop a fully automated, image-based diagnostic system for early diagnosis of pulmonary nodules that may lead to lung cancer. In this paper, we focus on generating new probabilistic models for the estimated growth ...

Ayman El-Baz; Georgy Gimel'Farb; Robert Falk; Mohamed Abou El-Ghar; Sabrina Rainey; David Heredia; Teresa Shaffer

2009-10-01T23:59:59.000Z

391

Relativistic Multireference Many-body Perturbation Theory for Open-shell Ions with Multiple Valence Shell Electrons: the Transition Rates and Lifetimes of the Excited Levels in Chlorinelike Fe X  

SciTech Connect

A recently developed relatistic multireference many-body perturbation theory based on multireference configuration-interaction wavefunctions as zeroth order wavefunctions is outlined. The perturbation theory employs a general class of configuration-interaction wve functions as reference functions, and thus is applciable to multiple open valence shell systems with near degeneracy of a manifold of strongly interacting configurations. Multireference many-body perturbation calculations are reported for the ground and excited states of chlorine-like Fe X in which the near degeneracy of a manifold of strongly interacting configurations mandates a multireference treatment. Term energies of a total of 83 excited levels arising from the 3s{sup 2}3p{sup 5}, 3s3p{sup 6}, 3s{sup 2}3p{sup 4}3d, 3s3p{sup 5}3d, and 3s{sup 2}3p{sup 3}3d{sup 2} configurations of the ion are evaluated to high accuracy. Transition rates associated with E1/M1/E2/M2/E3 radiative decays and lifetimes of a number of excited levels are calculated and compared with laboratory measurements to critically evaluate recent experiments.

Ishikawa, Y; Santana, J A; Tr?bert, E

2009-09-30T23:59:59.000Z

392

The use of polarized light for skin cancer detecton  

E-Print Network (OSTI)

Over 50,000 people per year will be diagnosed with skin cancer in one of its various forms, making it the seventh most common form of cancer in the United States. Currently the only method to diagnose suspicious lesions is visual inspection and subsequent biopsy of suspicious lesions. Many cancerous lesions are missed and many benign lesions are biopsied using these techniques. This process is painful and expensive. The proposed research is driven by the need for a non-invasive skin cancer detection system. Presented here is a method for the optical determination of cancerous tissue using polarized light. This thesis describes the development of a polarimetric imaging system including its calibration and testing. In addition, experiments are performed to simulate changes in tissue, such as increased size of scatterers and increased scattering and absorption coefficients that often accompany tissue changes as it becomes cancerous. The effects of these simulated changes are tested on the Polarimetric imaging system in order to quantify changes in the Mueller matrix caused by the perturbations, and ultimately to relate them to observed changes in the Mueller matrices of cancerous and non-cancerous tissue. Finally, the Polarimetric imaging system is used to determine the Mueller matrix of cancerous and non-cancerous tissue to assess the system's capabilities for skin cancer diagnosis.

DeLaughter, Aimee Hill

2002-01-01T23:59:59.000Z

393

doi:10.5402/2011/617082 Research Article Epithelial Ovarian Cancer and the Occurrence of Skin Cancer in  

E-Print Network (OSTI)

Copyright © 2011 Catharina C. van Niekerk et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Background. Patients with epithelial ovarian cancer have a high risk of (non-)melanoma skin cancer. The association between histological variants of primary ovarian cancer and skin cancer is poorly documented. Objectives. To further evaluate the risk of skin cancer based on the histology of the epithelial ovarian cancer. Methods. A cross-sectional study within a large populationbased dataset. Results. Skin cancer was found in 2.7 % (95 % CI: 2.3–3.1) of the 5366 individuals forming our dataset. The odds ratio (OR) for endometrioid cancer in the ovary to skin cancer in the under 50 age group was 8.9 (95 % CI: 3.2–25.0). The OR decreased in older patients to 1.2. Conclusions. Patients with epithelial ovarian malignancies show an increased risk of skin cancer. A significantly increased risk (4.3%) for endometrioid ovarian cancer was found in the group aged under 50. 1.

Isrn Obstetrics; Catharina C. Van Niekerk; Johan Bulten; Andrél. M. Verbeek

2011-01-01T23:59:59.000Z

394

Deans Club Lifetime Abbott Laboratories Fund  

E-Print Network (OSTI)

Northeast Correctional Complex Jerry Hayes, Health Administrator 5249 Highway 67 West Mountain City, TN Critical access hospital Wellmont - Hawkins County Memorial Hospital Fred Pelle, CEO 851 Locust St

Peterson, Blake R.

395

Hydrolysis Kinetics and Lifetime Prediction for Polycarbonate ...  

Science Conference Proceedings (OSTI)

... Typical Meteorological Year (TMY) data http://rredc.nrel.gov/solar/old_data/ ... activation energy (E a ) ... EK Euranto and NJ Cleve, Acta Chem. ...

2013-03-15T23:59:59.000Z

396

2013 ICCES Lifetime Achievement Medal - Vinod Tewary  

Science Conference Proceedings (OSTI)

... WA. Dr. Tewary will be recognized at their annual banquet and will present an award lecture on his research at that time. A ...

2013-05-08T23:59:59.000Z

397

Novel techniques applied to polymer lifetime predictions  

Science Conference Proceedings (OSTI)

A study aimed at testing the Arrhenius life prediction approach is described. After aging elastomeric materials at several elevated (accelerated) temperatures, a modulus profiling apparatus was used to demonstrate the complicated diffusion-limited oxidation anomalies are typically present under accelerated oven-aging conditions. By using surface modulus results (oxidation less to a monotonic increase in modulus), estimates are made of the true activation energy (E{sub a}) appropriate to the oxidation reactions dominating degradation. Even though macroscopic properties should be influenced by the diffusion-limited oxidation complications, ultimate tensile elongation results were found to be correlated to the true E{sub a}. This implies that cracks initiate at the hardened surface of the material and then quickly propagate through the less oxidized interior. If values of E{sub a} obtained from accelerated exposures can be determined and rationalized, another important question involves the Arrhenius assumption that E{sub a} remains constant in the extrapolation region. Preliminary data from two ultra-sensitive techniques (oxygen consumption and microcalorimetry) aimed at testing this fundamental assumption are described.

Gillen, K.T.; Wise, J.; Clough, R.L.

1993-12-31T23:59:59.000Z

398

Magnetically Trapped Neutron Lifetime Experiment (continued ...  

Science Conference Proceedings (OSTI)

... About 35 % of the initial electron energy goes into the production of extreme ultraviolet (EUV) photons from singlet decays, corresponding to ...

2013-07-22T23:59:59.000Z

399

Corrosion, Coating Protection and Lifetime Prediction  

Science Conference Proceedings (OSTI)

Mar 5, 2013 ... Corrosion of Membrane Materials for Hydrogen Separation from Coal-Derived Syngas: Omer Dogan1; Benjamin Nielsen2; 1DOE National ...

400

Reliability and Lifetime Prediction for Ceramic Components  

SciTech Connect

Ceramic materials are used extensively in non-nuclear components in the weapons stockpile including neutron tubes, stronglinks, weaklinks, batteries, and current/voltage stacks. Ceramics also perform critical functions in electronics, passively as insulators and actively as resistors and capacitors, Glass and ceramic seals also provide hermetic electrical feedthrus in connectors for many weapons components.

Vedula, V.R.; Glass, S.J.; Monroe, S.L.; Neilsen, M.K.; Newton, C.

1999-01-11T23:59:59.000Z

Note: This page contains sample records for the topic "incremental lifetime cancer" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


401

MATERIALS EDUCATION: OPPORTUNITIES OVER A LIFETIME  

Science Conference Proceedings (OSTI)

Sponsored by: Federation of Materials Societies, and University Materials Council. ...... Outreach and Educational Activities from the University of Kentucky.

402

Analyzing Geographic Patterns of Disease Incidence: Rates of Late-Stage Colorectal Cancer in Iowa  

Science Conference Proceedings (OSTI)

This study, using geocodes of the locations of residence of newly diagnosed colorectal cancer patients from the Iowa Cancer Registry, computed continuous spatial patterns of late-stage rates of colorectal cancer in Iowa. Variations in rates in intrahospital ... Keywords: GIS, SEER, colorectal cancer, geocodes, late-stage cancer

Gerard Rushton; Ika Peleg; Aniruddha Banerjee; Geoffrey Smith; Michele West

2004-06-01T23:59:59.000Z

403

Cancer-fighting treatment gets boost from Isotope Production Facility  

NLE Websites -- All DOE Office Websites (Extended Search)

Cancer-fighting treatment gets boost from Isotope Production Cancer-fighting treatment gets boost from Isotope Production Facility Cancer-fighting treatment gets boost from Isotope Production Facility New capability expands existing program, creates treatment product in quantity. April 13, 2012 Medical Isotope Work Moves Cancer Treatment Agent Forward Medical Isotope Work Moves Cancer Treatment Agent Forward - Los Alamos scientist Meiring Nortier holds a thorium foil test target for the proof-of-concept production experiments. Research indicates that it will be possible to match current annual, worldwide production of Ac-225 in just two to five days of operations using the accelerator at Los Alamos and analogous facilities at Brookhaven. Alpha particles are energetic enough to destroy cancer cells but are unlikely to move beyond a tightly controlled target region and destroy

404

Editorial Breast Cancer Research – the first ten years  

E-Print Network (OSTI)

Breast Cancer Research was launched in 1999 with the aim of providing a home for translational research in breast cancer [1]. The field of translational research has advanced considerably over the past ten years, and the journal has evolved over this time to meet the changing needs of the breast cancer research community. As we celebrate Breast Cancer Research’s 10 th birthday, we take this opportunity to reflect on the journal’s growth over the last decade. Breast Cancer Research is committed to open access publication of research articles, and remains the only journal in the breast cancer field dedicated to open access. Open access means research is universally and freely available via the Internet. Authors retain their own copyright, allowing them to grant any third party the right to use, reproduce and disseminate the article. Open access has broad benefits both

Frances Mulvany; Bruce Aj Ponder

2008-01-01T23:59:59.000Z

405

6.21 Improving Neutron Beams for Cancer Treatment  

NLE Websites -- All DOE Office Websites (Extended Search)

the most advanced epithermal neutron source in the world for cancer treatment. Social Impact: Preliminary trials of BNCT therapy supported by the Office of Science have shown...

406

Neutron Imaging Explored as Complementary Technique for Improving Cancer  

NLE Websites -- All DOE Office Websites (Extended Search)

Neutron Imaging Explored as Complementary Technique for Improving Cancer Neutron Imaging Explored as Complementary Technique for Improving Cancer Detection August 05, 2013 Researcher Maria Cekanova analyzes the neutron radiographs of a canine breast tumor (black color in top image of monitor screen) using the software to visualize in color the various intensities of neutron transmissions through the breast tissue. ORNL and University of Tennessee collaboration now analyzing first results from neutron radiographs of cancerous tissue samples Today's range of techniques for detection of breast and other cancers include mammography, computed tomography (CT), magnetic resonance imaging (MRI), ultrasound, positron emission tomography (PET), and optical imaging. Each technology has advantages and disadvantages, with limitations either

407

Former Worker Program - Early Lung Cancer Detection Program  

NLE Websites -- All DOE Office Websites (Extended Search)

Former Worker Program (FWP) Former Worker Program (FWP) Home Covered Sites/Populations › Construction Worker Screening Projects › Production Worker Screening Projects › Supplemental Screening Program › Beryllium Vendor Screening Program Upcoming Events Program Implementation Outreach Medical Screening - Conventional Medical Screening - Early Lung Cancer Detection Communicating Results Protecting Participant Information Sharing De-identified Data Chronic Beryllium Disease Awareness Joint Outreach Task Group (JOTG) Worker Testimonials Contact Us FWP Scientific Publications FWP Documents Related Links Office of Health and Safety Home Page HSS Logo Early Lung Cancer Detection Program Former Worker Medical Screening Program (FWP) Since 2000, DOE has made screening for occupational lung cancer with low-dose helical computed tomography (CT) scans available to workers at high risk for lung cancer. Because former workers undertook essential activities to fulfill the Department's mission, many of them were at risk for lung cancer. Through the FWP, DOE initiated the Early Lung Cancer Detection (ELCD) program using low-dose helical CT scans to detect lung cancers at an earlier, more treatable stage. Lung cancer results in about 160,000 deaths in the U.S. every year. The most common causes of lung cancer are long-term exposures to tobacco smoke and residential radon emissions, but occupational hazards, such as asbestos and ionizing radiation, also cause or contribute to the disease.

408

What Connects Rat Tails to Cancer and Heart Disease?  

NLE Websites -- All DOE Office Websites (Extended Search)

What Connects Rat Tails to Cancer and Heart Disease? Collagen is the main (and most abundant) protein in all mammalian connective tissues, including those of the heart, lungs,...

409

Progress on Production of Alpha-emitting Radioisotopes for Cancer...  

Office of Science (SC) Website

Progress on Production of Alpha-emitting Radioisotopes for Cancer Therapy Nuclear Physics (NP) NP Home About Research Facilities Science Highlights Benefits of NP Funding...

410

Molecular cytogenetic characterization of a human thyroid cancer cell line  

E-Print Network (OSTI)

gland during the Chernobyl catastrophe. Environmental Healthradiation as a result of the Chernobyl disaster. Cancer 76,1986 nuclear accident in Chernobyl, Ukraine. In the twelve

2006-01-01T23:59:59.000Z

411

Tumor initiating but differentiated luminal-like breast cancer ...  

... Oslo, Norway; cCancer Stem Cell Innovation Center, Oslo ... the above explanation always must be ... Fold change analysis of the miRNA microarray ...

412

DNA repair: Dynamic defenders against cancer and aging  

E-Print Network (OSTI)

developmental defects; premature aging; brittle hair; scalypredisposition and premature aging. Acknowledgements. Weagainst cancer and aging Jill O. Fuss and Priscilla K.

Fuss, Jill O.; Cooper, Priscilla K.

2006-01-01T23:59:59.000Z

413

Serum 25-hydroxyvitamin D and risk of breast cancer  

E-Print Network (OSTI)

The relationship of solar radiation to cancer mortality ininvolving exposure to solar radiation. Prev Med. 1990;19:and amount of solar radiation in 49 US metropolitan areas

Mohr, Sharif Burgette

2012-01-01T23:59:59.000Z

414

Cancer research at Berkeley Lab: the intersection of science...  

NLE Websites -- All DOE Office Websites (Extended Search)

Climate September Conservation October Geosciences November Chemistry December Health Cancer research at Berkeley Lab: the intersection of science and health Mention the...

415

Translational Research on Esophageal Cancer: From Cell Line to Clinic.  

E-Print Network (OSTI)

??Worldwide esophageal cancer is a signifi cant and an increasing health problem. In 2005, there were 497,700 new cases, and the prevalence is expected to… (more)

Boonstra, J.J.

2011-01-01T23:59:59.000Z

416

Early clinical cancer trials: Proof of concept and beyond.  

E-Print Network (OSTI)

??Over the last few decades clinical cancer research has developed at accelerating speed, resulting in a tremendous increase of knowledge with regard to tumour biology,… (more)

Konings, I.R.H.M.

2011-01-01T23:59:59.000Z

417

Stromal Modulation of Radiation Carcinogenesis in Breast Cancer  

E-Print Network (OSTI)

and age at exposure for all solid cancers as a group and many individual sites as a consequence of the atomic

Nguyen, David Hiendat Hua

2011-01-01T23:59:59.000Z

418

Yeast-based vaccine approaches to cancer immunotherapy  

E-Print Network (OSTI)

Saccharomyces cerevisiae stimulates dendritic cells and represents a promising candidate for cancer immunotherapy development. Effective cross-presentation of antigen delivered to dendritic cells is necessary for successful ...

Howland, Shanshan W

2008-01-01T23:59:59.000Z

419

Improved Treatment of X-ray Resistant & Inoperable Cancers ...  

If the electron beam can be transported to the internal cancer without exposure to tissue, ... This figure shows a comparison of X-ray radiation ...

420

Medical Imaging for Breast Cancer - Reducing the Need for Biopsy  

Jefferson Lab is a Department of Energy national laboratory for nuclear physics research. ... Medical Imaging for Breast Cancer - Reducing the Need for Biopsy

Note: This page contains sample records for the topic "incremental lifetime cancer" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


421

Radioisotopes for Medical Diagnostics and Cancer Therapy at BNL...  

Office of Science (SC) Website

Radioisotopes for Medical Diagnostics and Cancer Therapy at BNL Nuclear Physics (NP) NP Home About Research Facilities Science Highlights Benefits of NP Spinoff Applications...

422

From Bombs to Breast Cancer Imaging: Los Alamos National Laboratory  

Science Conference Proceedings (OSTI)

In the United States, one in eight women will be affected by breast cancer. According to the American Cancer Society, breast cancer is the most commonly diagnosed - as well as the second most fatal - cancer in American women. It is estimated that there will be nearly 200,000 diagnoses of breast cancer this year; more than 40,000 of these will be fatal. Although advances in medical technologies have greatly increased the odds of surviving the disease, the increase in screenings has not resulted in a significant reduction in the breast cancer mortality rate. Moreover, recent studies have even suggested that an increase in these methods might, in itself, cause cancer. A new tool for early detection and diagnosis of breast cancer, supported by an award from the Breast Cancer Research Program (BCRP) of the Congressionally Directed Medical Research Programs of Department of Defense, could give women a new advantage in the fight against breast cancer. This LANL-led project will integrate ultrasound tomography (UST) with recent discoveries in the field of cell and tissue biomechanics to improve breast cancer detection and characterization. UST uses ultrasound waves instead of X-rays to identify and characterize breast tumors. This technology reveals small mechanical-property changes within the breast. These changes are often the earliest signs of breast cancer. Additionally, UST is effective for women with dense breast tissue, who have a higher risk of developing breast cancer. Because the technology does not use radiation, UST can also be used as frequently as needed for women with a high risk of developing breast cancer. In contrast, mammography, the only routine breast-cancer screening tool currently available, is not effective for women with dense breast tissue and may come with unwanted side-effects caused by ionizing radiation. UST has great potential to become an alternative breast-cancer screening tool because of UST's advantages and benefits over mammography. Currently, there is fierce debate surrounding the age at which breast cancer screening should begin, and once begun, how often it should occur. The American Cancer Society recommends yearly mammograms starting at age 40. On the other hand, the U.S. Preventive Services Task Force recommends against routine so early. Rather, the Task Force recommends biennial mammography screening for women aged 50 to 74 years. The ten-year discrepancy in the onset of screening results from recent data suggesting that the frequent use of X-ray radiation during screenings could potentially increase the likelihood of developing cancer. This danger is increased by the low sensitivity and accuracy of mammograms, which sometimes require multiple screenings to yield results. Furthermore, mammograms are often not only inaccurate, but average appalling misdiagnoses rates: about 80% false positives and 15% false negatives. These misdiagnoses lead to unwarranted biopsies at an estimated health care cost of $2 billion per year, while at the same time, resulting in excessive cases of undetected cancer. As such, the National Cancer Institute recommends more studies on the advantages of types and frequency of screenings, as well as alternative screening options. The UST technology developed at LANL could be an alternative option to greatly improve the specificity and sensitivity of breast cancer screening without using ionizing radiation. LANL is developing high-resolution ultrasound tomography algorithms and a clinical ultrasound tomography scanner to conduct patient studies at the UNM Hospital. During UST scanning, the patient lies face-down while her breast, immersed in a tank of warm water, is scanned by phased-transducer arrays. UST uses recorded ultrasound signals to reconstruct a high-resolution three-dimensional image of the breast, showing the spatial distribution of mechanical properties within the breast. Breast cancers are detected by higher values of mechanical properties compared to surrounding tissues. Thus, high-resolution breast images obtained using LANL's novel UST algorithms ha

Martineau, Rebecca M [Los Alamos National Laboratory

2012-07-26T23:59:59.000Z

423

Proteomic Study of Oral Cancer Stem-Like Cells and Bone Marrow Cell Treatment for Sjögren's Syndrome  

E-Print Network (OSTI)

Carcinoma. Clinical Cancer Research, 2008. 14(13): p. 4085-Cell Lung Cancer. Cancer Research, 2008. 68(15): p. 6065-Inducible Factor-1?. Cancer Research, 2006. 66(7): p. 3688-

Misuno, Kaori

2013-01-01T23:59:59.000Z

424

A multigene predictor of metastatic outcome in early stage hormone receptor-negative and triple-negative breast cancer  

E-Print Network (OSTI)

breast cancer. Breast Cancer Research 2010 12:R85. SubmitYau et al. Breast Cancer Research 2010, 12:R85 http://cited Yau et al. Breast Cancer Research 2010, 12:R85 http://

Yau, Christina; Esserman, Laura; Moore, Dan H; Waldman, Fred; Sninsky, John; Benz, Christopher C

2010-01-01T23:59:59.000Z

425

The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression  

E-Print Network (OSTI)

migration and invasion. Cancer Research 65, 11572- Hiraguri,cancer cell lines. Cancer Research 58, 1972-1977. Irie,of tumor cells. Cancer Research 47, 3239-3245. Ashburner,

2008-01-01T23:59:59.000Z

426

The Role of Non-Mutated Signaling Networks and Inflammatory Cytokines in the Initiation and Progression of Prostate Cancer  

E-Print Network (OSTI)

for the AACR Special Conference in Cancer Research: Advancesin Prostate Cancer Research, Orlando, FL. Smith DA, Zong Y,Cancer Cells. Clinical Cancer Research. 2003;9:370–6. Smith

Smith, Daniel Alan

2013-01-01T23:59:59.000Z

427

WE?A?213AB?01: Second Cancers from Radiation Therapy Procedures  

Science Conference Proceedings (OSTI)

Second Cancers are the most common late effect among long?term cancer survivors. Radiation has been a known risk factor for cancer induction based on atomic bomb survivor follow?up. Over the last few decades

S Kry; R Howell

2012-01-01T23:59:59.000Z

428

Recent breast cancer incidence trends according to hormone therapy use: the California Teachers Study cohort  

E-Print Network (OSTI)

breast cancer incidence trends according to hormone therapyA, Ward E, Thun MJ: Recent trends in breast cancer incidencein France: a paradoxical trend. Bull Cancer 10. Katalinic A,

2010-01-01T23:59:59.000Z

429

Recent breast cancer incidence trends according to hormone therapy use: the California Teachers Study cohort  

E-Print Network (OSTI)

Study cohort. Breast Cancer Research 2010 12:R4. Submit yourMarshall et al. Breast Cancer Research 2010, 12:R4 http://Marshall et al. Breast Cancer Research 2010, 12:R4 http://

2010-01-01T23:59:59.000Z

430

Separation of cancer cells from peripheral blood mononuclear cells using pH control and dielectrophoresis  

E-Print Network (OSTI)

System. Clinical Cancer Research, 2007. 13(3): p.920 – 928.Solid Tumors. Clinical Cancer Research, 1999. 5:p.1950-1960.Diseases. Clinical Cancer research, 2004. 10:p.6897-6904.

Pattanaik, Malisha

2009-01-01T23:59:59.000Z

431

Can A Virus Cause Cancer: A Look Into The History And Significance Of Oncoviruses  

E-Print Network (OSTI)

of Tumor Virology. Cancer Research. 68(19): 7693-7706. deof the role of viruses in cancer, research on the subject2004. Conncecting Viruses to Cancer: How Research Moves from

Rwazavian, Niema

2011-01-01T23:59:59.000Z

432

beta1 Integrin mediates an alternative survival pathway in breast cancer cells resistant to lapatinib  

E-Print Network (OSTI)

resistant to lapatinib. Breast Cancer Research 2011 13:R84.96. Huang et al. Breast Cancer Research 2011, 13:R84 http://Huang et al. Breast Cancer Research 2011, 13:R84 http://

2011-01-01T23:59:59.000Z

433

Survival and self-renewing capacity of breast cancer initiating cells during fractionated radiation treatment  

E-Print Network (OSTI)

radiation treatment. Breast Cancer Research 2010 12:R13.Lagadec et al. Breast Cancer Research 2010, 12:R13 http://Lagadec et al. Breast Cancer Research 2010, 12:R13 http://

2010-01-01T23:59:59.000Z

434

Development of alternating amphiphilic copolymers for targeted delivery applications in cancer  

E-Print Network (OSTI)

According to the American Cancer Society, approximately 1,479,000 new cases of cancer were expected to be diagnosed, while 562,340 Americans were expected to die from cancer in 2009 alone. Even though advances in early ...

Brower, Kevin P. (Kevin Peter)

2011-01-01T23:59:59.000Z

435

Dose Coverage Beyond the Gross Tumor Volume for Various Stereotactic Body Radiotherapy Planning Techniques Reporting Similar Control Rates for Stage I Non-Small-Cell Lung Cancer  

SciTech Connect

Purpose: To investigate the dose falloff region for various stereotactic body radiotherapy (SBRT) planning techniques used in the treatment of Stage I non-small-cell lung cancer reporting similar control rates. Methods and Materials: The SBRT plans were constructed on five patient data sets using seven different planning regimens. These regimens varied in the number of beams, number of fractions, prescription target, and prescribed dose used. For each case all regimens were planned using a common gross tumor volume (GTV). To compare dose falloff for the various regimens, resulting physical dose grids were converted into normalized total dose (NTD) grids. Furthermore, to determine the potential coverage of microscopic extension of the various regimens minimal peripheral NTD (NTD-MP{sub 100}) were calculated and plotted as a function of incremental volume expansions of the GTV. Results: Average values for NTD-MP{sub 100} varied over a range of 174 Gy at the GTV periphery, but this range fell to 10 Gy at a distance of 14 mm from the GTV. Of 35 plans, 23 resulted in potential microscopic extension coverage of 78% to 95%. Averages for five of seven regimens fell within the range of 80% to 85%. Results were negligibly affected when intrafraction motion effects were accounted for. Conclusions: Although average NTD-MP{sub 100} varied dramatically at the GTV, periphery values became similar at a distance of 14 mm from the GTV. With the exception of two, potential coverage of microscopic extension was similar for all planning techniques, with averages falling within a 5% range.

Arvidson, Noah B. [Department of Medical Physics, University of Wisconsin, Madison, WI (United States); Mehta, Minesh P. [Department of Human Oncology, University of Wisconsin, Madison, WI (United States); Tome, Wolfgang A. [Department of Medical Physics, University of Wisconsin, Madison, WI (United States); Department of Human Oncology, University of Wisconsin, Madison, WI (United States)], E-mail: tome@humonc.wisc.edu

2008-12-01T23:59:59.000Z

436

A Framework for Developing, Implementing, and Evaluating a Cancer Survivorship Curriculum for Medical Students  

E-Print Network (OSTI)

Effects of a dedicated curriculum. J Cancer Educ. 2007; 224,illness: Competencies for a curriculum for medical students.first year medical school curriculum. J Cancer Educ. 2004;

Uijtdehaage, Sebastian; Hauer, Karen E.; Stuber, Margaret; Rajagopalan, Shobita; Go, Vay L.; Wilkerson, LuAnn

2009-01-01T23:59:59.000Z

437

Cancer Screening in California: Findings from the 2001 California Health Interview Survey  

E-Print Network (OSTI)

American Cancer Society, California Division, and PublicDiabetes in California: CancerScreening in California: Findings from the 2001 California

Ponce, Ninez A.; Babey, Susan H.; Etzioni, David; Spencer, Benjamin A.; Brown, E. Richard R; Chawla, Neetu

2003-01-01T23:59:59.000Z

438

Questions and Answers About Female Breast Cancer What is Breast Cancer?  

E-Print Network (OSTI)

the radiation from a mammogram? Should I worry about this? Data from the atomic bomb survivors and other groups. The single most effective way a woman can detect early breast cancer is through routine mammography medical history · Physical exam which includes palpation of the breast and nearby lymph nodes · Imaging

439

Targeting NRF2 signaling for cancer chemoprevention  

SciTech Connect

Modulation of the metabolism and disposition of carcinogens through induction of cytoprotective enzymes is one of several promising strategies to prevent cancer. Chemopreventive efficacies of inducers such as dithiolethiones and sulforaphane have been extensively studied in animals as well as in humans. The KEAP1-NRF2 system is a key, but not unilateral, molecular target for these chemopreventive agents. The transcription factor NRF2 (NF-E2-related factor 2) is a master regulator of the expression of a subset of genes, which produce proteins responsible for the detoxication of electrophiles and reactive oxygen species as well as the removal or repair of some of their damage products. It is believed that chemopreventive enzyme inducers affect the interaction between KEAP1 and NRF2 through either mediating conformational changes of the KEAP1 protein or activating phosphorylation cascades targeting the KEAP1-NRF2 complex. These events in turn affect NRF2 stability and trafficking. Recent advances elucidating the underlying structural biology of KEAP1-NRF2 signaling and identification of the gene clusters under the transcriptional control of NRF2 are facilitating understanding of the potential pleiotropic effects of NRF2 activators and discovery of novel classes of potent chemopreventive agents such as the triterpenoids. Although there is appropriately a concern regarding a deleterious role of the KEAP1-NRF2 system in cancer cell biology, especially as the pathway affects cell survival and drug resistance, the development and the use of NRF2 activators as chemopreventive agents still holds a great promise for protection of normal cells from a diversity of environmental stresses that contribute to the burden of cancer and other chronic, degenerative diseases.

Kwak, Mi-Kyoung, E-mail: mkwak@ynu.ac.k [College of Pharmacy, Yeungnam University, 214-1 Dae-dong, Gyeongsan-si, Gyeongsangbuk-do 712-749 (Korea, Republic of); Kensler, Thomas W. [Department of Environmental Health Sciences, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD (United States)

2010-04-01T23:59:59.000Z

440

Narrow focus ultra-wideband antenna for breast cancer detection  

Science Conference Proceedings (OSTI)

A narrow focus ultra-wideband dielectric-filled antenna has been designed for the purpose of near-field breast cancer detection without the use of coupling media. Instead of immersing the antenna in a lossy liquid coupling medium, direct matching of ... Keywords: antenna feeds, antennas, breast cancer detection, directional, radar-based imaging, ultra-wide band

Daniel M. Hailu; Safieddin Safavi-Naeini

2009-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "incremental lifetime cancer" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


441

Integrative Genomic Approaches Identify IKBKE as a Breast Cancer Oncogene  

E-Print Network (OSTI)

. IKK3 acti- vates the nuclear factor-kappaB (NF-kB) path- way in both cell lines and breast cancers. These observations suggest a mechanism for NF-kB activation in breast cancer, implicate the NF-kB pathway

442

Lab Breakthrough: Nanomaterials Discoveries Lead to Possible Cancer  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Lab Breakthrough: Nanomaterials Discoveries Lead to Possible Cancer Lab Breakthrough: Nanomaterials Discoveries Lead to Possible Cancer Treatment Lab Breakthrough: Nanomaterials Discoveries Lead to Possible Cancer Treatment June 4, 2012 - 3:05pm Addthis Argonne nanoscientist Elena Rozhkova is studying ways to enlist nanoparticles to treat brain cancer. This nano-bio technology may eventually provide an alternative form of therapy that targets only cancer cells and does not affect normal living tissue. View the entire Lab Breakthrough playlist. Michael Hess Michael Hess Former Digital Communications Specialist, Office of Public Affairs What is a nano-bio catalyst? A nanoparticle that triggers specific reactions in cells. The particle attaches to unwanted (tumor) cells, and when researchers shine light on them, they kill the cells through oxidation.

443

Commentary Breast cancer and childhood anthropometry: emerging hypotheses?  

E-Print Network (OSTI)

In this issue of Breast Cancer Research, Baer and colleagues report a strong protective effect of childhood and adolescent body fatness on premenopausal breast cancer risk based on a large prospective study. Methodological issues are discussed, as are tentative biological interpretations regarding the findings. In this issue of Breast Cancer Research, Baer and colleagues [1] report a strong protective effect of childhood and adolescent body fatness on premenopausal breast cancer risk. The report is based on the Nurses ’ Health Study II, a prospective cohort study including 116,671 US female nurses, aged 25–42 years at recruitment in 1989, in which 1318 breast cancer cases occurred during 12 years of follow up. There were slightly stronger associations between average childhood and adolescent body fatness and

Cecilia Mk Magnusson; Andrew W Roddam

2005-01-01T23:59:59.000Z

444

A PET/CT directed, 3D ultrasound-guided biopsy system for prostate cancer  

Science Conference Proceedings (OSTI)

Prostate cancer affects 1 in 6 men in the USA. Systematic transrectal ultrasound (TRUS)-guided biopsy is the standard method for a definitive diagnosis of prostate cancer. However, this "blind" biopsy approach can miss at least 20% of prostate cancers. ... Keywords: 3D ultrasound imaging, PET/CT, image segmentation, imageguided biopsy, molecular imaging, nonrigid image registration, prostate cancer, wavelet transform

Baowei Fei; Viraj Master; Peter Nieh; Hamed Akbari; Xiaofeng Yang; Aaron Fenster; David Schuster

2011-09-01T23:59:59.000Z

445

The improvement of breast cancer prognosis accuracy from integrated gene expression and clinical data  

Science Conference Proceedings (OSTI)

Predicting the accurate prognosis of breast cancer from high throughput microarray data is often a challenging task. Although many statistical methods and machine learning techniques were applied to diagnose the prognosis outcome of breast cancer, they ... Keywords: Breast cancer prognosis, Cancer classification, Clinical data, Gene expression, Gene selection, Genetic algorithm, Support vector machine

Austin H. Chen; Chenyin Yang

2012-04-01T23:59:59.000Z

446

PROCEEDINGS Open Access The possible prevention of cancer  

E-Print Network (OSTI)

The prevention of the infectious diseases was accomplished long before there was any understanding of the molecular biology of bacteria and viruses. As for cancer, the sharp drop in frequency of the once-commonest lethal cancer, stomach cancer, was achieved without any contribution from biological research, and the current drop in lung cancer is the end-result of the observation by epidemiologists that most lung cancer is caused by smoking. So the basis for both these triumphs was essentially empirical and owed nothing to biological research. This paper discusses how molecular biology can now offer the possibility of large-scale protection against cancer. Article Research into cancer has in the past been largely managedbydoctorsandtheemphasishastendedtobeon finding new treatments rather than on prevention. But it is quite clear that life expectancy in the industrialised world had almost doubled by the time the first antibiotics were discovered [1], and this must therefore have been achieved by prevention of the major infectious diseases rather than by devising better forms of treatment.

John Cairns

2009-01-01T23:59:59.000Z

447

Princeton University, Physics 311/312 Lifetime of the Muon, Page 1 LIFETIME OF THE MUON  

E-Print Network (OSTI)

, Discriminators, Logic Gates, Attenuators (small brass BNC connectors with attenuation factor stamped on it

448

Review Genomic approaches to research in lung cancer  

E-Print Network (OSTI)

The medical research community is experiencing a marked increase in the amount of information available on genomic sequences and genes expressed by humans and other organisms. This information offers great opportunities for improving our understanding of complex diseases such as lung cancer. In particular, we should expect to witness a rapid increase in the rate of discovery of genes involved in lung cancer pathogenesis and we should be able to develop reliable molecular criteria for classifying lung cancers and predicting biological properties of individual tumors. Achieving these goals will require collaboration by scientists with specialized expertise in medicine, molecular biology, and decision-based statistical analysis.

Edward Gabrielson

2000-01-01T23:59:59.000Z

449

Self-reported chemicals exposure, beliefs about disease causation, and risk of breast cancer in the Cape Cod Breast Cancer and Environment Study: a case-control study  

E-Print Network (OSTI)

2&1&0&1&6&0]. 34. Cape Cod Breast Cancer and the EnvironmentSpring Institute: Cape Cod Breast Cancer and Environmentbetween residence on Cape Cod, Massachusetts, and breast

Zota, Ami R; Aschengrau, Ann; Rudel, Ruthann A; Brody, Julia

2010-01-01T23:59:59.000Z

450

The relationship of cognitive, emotional, and interpersonal factors to screening and health-promoting behaviors among sisters of breast cancer patients.  

E-Print Network (OSTI)

??While sisters of breast cancer patients are at increased risk for developing breast cancer due to their family cancer history and age, little research with… (more)

Hartman, Sheri Jacobs

2008-01-01T23:59:59.000Z

451

DOE Laboratories Help Develop Promising New Cancer Fighting Drug,  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Laboratories Help Develop Promising New Cancer Fighting Drug, Laboratories Help Develop Promising New Cancer Fighting Drug, Vemurafenib DOE Laboratories Help Develop Promising New Cancer Fighting Drug, Vemurafenib August 18, 2011 - 1:03pm Addthis Powerful X-Rays Enable Development of Successful Treatment for Melanoma and Other Life-Threatening Diseases WASHINGTON, DC - Powerful X-ray technology developed at the U.S. Department of Energy's (DOE's) national laboratories is revealing new insights into diseases ranging from Alzheimer's to the swine flu, and, most recently, enabled the discovery of a groundbreaking new drug treatment for malignant melanoma, the deadliest form of skin cancer. The drug, Zelboraf (vemurafenib), received Food and Drug Administration (FDA) approval on Wednesday. In showing the structures of diseased and

452

Enzyme Structure Provides Insights into Cancer and Aging  

NLE Websites -- All DOE Office Websites (Extended Search)

Enzyme Structure Provides Insights into Cancer and Aging Print Enzyme Structure Provides Insights into Cancer and Aging Print XPD helicase is an enzyme that unwinds the DNA double helix; it is one component of an essential repair mechanism that maintains the integrity of DNA. XPD is unique, however, in that pinpoint mutations of this single protein are responsible for three different human diseases: in xeroderma pigmentosum (XP), extreme sensitivity to sunlight promotes cancer; Cockayne syndrome (CS) involves stunted growth and premature aging; trichothiodystrophy (TTD), characterized by brittle hair and scaly skin, is another form of greatly accelerated aging. At the ALS, researchers from Berkeley Lab and The Scripps Research Institute recently solved the structure of XPD. The structure gives novel insight into the processes of aging and cancer by revealing how discrete flaws-as seemingly insignificant as a change in either of two adjacent amino acid residues-can lead to diseases with completely different physical manifestations.

453

Enzyme Structure Provides Insights into Cancer and Aging  

NLE Websites -- All DOE Office Websites (Extended Search)

Enzyme Structure Provides Insights into Cancer and Aging Print Enzyme Structure Provides Insights into Cancer and Aging Print XPD helicase is an enzyme that unwinds the DNA double helix; it is one component of an essential repair mechanism that maintains the integrity of DNA. XPD is unique, however, in that pinpoint mutations of this single protein are responsible for three different human diseases: in xeroderma pigmentosum (XP), extreme sensitivity to sunlight promotes cancer; Cockayne syndrome (CS) involves stunted growth and premature aging; trichothiodystrophy (TTD), characterized by brittle hair and scaly skin, is another form of greatly accelerated aging. At the ALS, researchers from Berkeley Lab and The Scripps Research Institute recently solved the structure of XPD. The structure gives novel insight into the processes of aging and cancer by revealing how discrete flaws-as seemingly insignificant as a change in either of two adjacent amino acid residues-can lead to diseases with completely different physical manifestations.

454

Enzyme Structure Provides Insights into Cancer and Aging  

NLE Websites -- All DOE Office Websites (Extended Search)

Enzyme Structure Provides Insights into Cancer and Aging Print Enzyme Structure Provides Insights into Cancer and Aging Print XPD helicase is an enzyme that unwinds the DNA double helix; it is one component of an essential repair mechanism that maintains the integrity of DNA. XPD is unique, however, in that pinpoint mutations of this single protein are responsible for three different human diseases: in xeroderma pigmentosum (XP), extreme sensitivity to sunlight promotes cancer; Cockayne syndrome (CS) involves stunted growth and premature aging; trichothiodystrophy (TTD), characterized by brittle hair and scaly skin, is another form of greatly accelerated aging. At the ALS, researchers from Berkeley Lab and The Scripps Research Institute recently solved the structure of XPD. The structure gives novel insight into the processes of aging and cancer by revealing how discrete flaws-as seemingly insignificant as a change in either of two adjacent amino acid residues-can lead to diseases with completely different physical manifestations.

455

A Targeted Cancer Treatment using Nanomaterials | Advanced Photon Source  

NLE Websites -- All DOE Office Websites (Extended Search)

When Roots Follow the Path of Least Resistance When Roots Follow the Path of Least Resistance Perfecting Catalytic Arrays A Stable Open Framework with Wide Open Spaces Pumping Through the Middle Crust Looking for Ways to Improve Vaccines Against the Deadly Rotavirus Science Highlights Archives: 2013 | 2012 | 2011 | 2010 2009 | 2008 | 2007 | 2006 2005 | 2004 | 2003 | 2002 2001 | 2000 | 1998 | Subscribe to APS Science Highlights rss feed A Targeted Cancer Treatment using Nanomaterials AUGUST 27, 2009 Bookmark and Share Optical fluorescent imaging of the TiO2-mAb binding to the single brain cancer cells. The bare titianium dioxide nanoparticle bonds with an antibody and attaches itself to brain cancer cells. When exposed to concentrated white light, the titanium dioxide creates free radicals of oxygen that cause the cancer cells to die. Image courtesy of Argonne

456

Breaking a Pocket of Resistance in the Fight Against Cancer  

NLE Websites -- All DOE Office Websites (Extended Search)

Breaking a Pocket of Resistance in Breaking a Pocket of Resistance in the Fight Against Cancer Breaking a Pocket of Resistance in the Fight Against Cancer Print Thursday, 12 December 2013 11:55 ras protein The new class of inhibitors interacts with a specific mutation (Glycine to Cysteine) associated with a number of types of lung cancer. Mutations in the protein K-RAS are a very common cause for certain types of human cancers and are generally associated with a poor response to standard therapies. RAS, an abbreviation of Rat Sarcoma, is a nucleotide binding protein that responds to chemical signals (nucleotides). When in the "on" state, RAS activates other proteins, resulting in a cascade of biochemical processes; in the "off" state, RAS remains inactive. Mutations in the RAS

457

Evaluation of nanoparticles-based thermotherapy for cancer  

E-Print Network (OSTI)

Under alternating magnetic field, superparamagnetic iron oxide nanoparticles can be used to generate heat for the treatment of cancer. With suitable coating, these nanoparticles are biocompatible, stable in solution, and ...

Wiryaatmadja, Edwina

2007-01-01T23:59:59.000Z

458

Iran Thomas Auditorium, 8600 Fighting Cancer with Nanoparticle...  

NLE Websites -- All DOE Office Websites (Extended Search)

October 13, 2011 4:00 pm Iran Thomas Auditorium, 8600 Fighting Cancer with Nanoparticle Medicines Mark E. Davis Chemical Engineering California Institute of Technology CNMS D D I I...

459

Lung cancer epidemiology in New Mexico uranium miners  

SciTech Connect

This investigation assesses the health effects of radon progeny exposure in New Mexico uranium miners. Cumulative exposures sustained by most New Mexico miners are well below those received earlier in the Colorado Plateau. This project utilizes the research opportunity offered by New Mexico miners to address unresolved issues related to radon progeny exposure: (1) the lung cancer risk of lower levels of exposure, (2) interaction between radon progeny exposure and cigarette smoking in the causation of lung cancer, (3) the relationship between lung cancer histologic type and radon progeny exposure, and (4) possible effects of radon progeny exposure other than lung cancer. A cohort study of 3800 men with at least one year of underground uranium mining experience in New Mexico is in progress. Results are discussed.

Samet, J.M.

1991-11-01T23:59:59.000Z

460

Enzyme Structure Provides Insights into Cancer and Aging  

NLE Websites -- All DOE Office Websites (Extended Search)

Enzyme Structure Provides Insights into Cancer and Aging Print XPD helicase is an enzyme that unwinds the DNA double helix; it is one component of an essential repair mechanism...

Note: This page contains sample records for the topic "incremental lifetime cancer" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


461

Enzyme Structure Provides Insights into Cancer and Aging  

NLE Websites -- All DOE Office Websites (Extended Search)

Bioscience Enzyme Structure Provides Insights into Cancer and Aging Print XPD helicase is an enzyme that unwinds the DNA double helix; it is one component of an essential repair...

462

Analysis of alterations in the human cancer genome  

E-Print Network (OSTI)

Aneuploidy, an abnormal complement of chromosomes, is present in approximately 90% of human malignancies. Despite over 100 years of research, many questions remain regarding the contribution of aneuploidy to the cancer ...

Carter, Scott L. (Scott Lambert)

2011-01-01T23:59:59.000Z

463

Research Sheds Light on Workings of Anti-cancer Drug  

NLE Websites -- All DOE Office Websites (Extended Search)

Research Sheds Light on Workings of Anti-cancer Drug The copper sequestering drug tetrathiomolybdate (TM) has been shown in studies to be effective in the treatment of Wilson...

464

Nested methylation-specific polymerase chain reaction cancer detection method  

DOE Patents (OSTI)

A molecular marker-based method for monitoring and detecting cancer in humans. Aberrant methylation of gene promoters is a marker for cancer risk in humans. A two-stage, or "nested" polymerase chain reaction method is disclosed for detecting methylated DNA sequences at sufficiently high levels of sensitivity to permit cancer screening in biological fluid samples, such as sputum, obtained non-invasively. The method is for detecting the aberrant methylation of the p16 gene, O 6-methylguanine-DNA methyltransferase gene, Death-associated protein kinase gene, RAS-associated family 1 gene, or other gene promoters. The method offers a potentially powerful approach to population-based screening for the detection of lung and other cancers.

Belinsky, Steven A. (Albuquerque, NM); Palmisano, William A. (Edgewood, NM)

2007-05-08T23:59:59.000Z

465

Investigating immune surveillance, tolerance, and therapy in cancer  

E-Print Network (OSTI)

Maximizing the potential of cancer immunotherapy requires model systems that closely recapitulate human disease to study T cell responses to tumor antigens and to test immune therapeutic strategies. Current model systems ...

Cheung, Ann F

2009-01-01T23:59:59.000Z

466

DOE Laboratories Help Develop Promising New Cancer Fighting Drug,  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Laboratories Help Develop Promising New Cancer Fighting Drug, Laboratories Help Develop Promising New Cancer Fighting Drug, Vemurafenib DOE Laboratories Help Develop Promising New Cancer Fighting Drug, Vemurafenib August 18, 2011 - 1:03pm Addthis Powerful X-Rays Enable Development of Successful Treatment for Melanoma and Other Life-Threatening Diseases WASHINGTON, DC - Powerful X-ray technology developed at the U.S. Department of Energy's (DOE's) national laboratories is revealing new insights into diseases ranging from Alzheimer's to the swine flu, and, most recently, enabled the discovery of a groundbreaking new drug treatment for malignant melanoma, the deadliest form of skin cancer. The drug, Zelboraf (vemurafenib), received Food and Drug Administration (FDA) approval on Wednesday. In showing the structures of diseased and

467

Enzyme Structure Provides Insights into Cancer and Aging  

NLE Websites -- All DOE Office Websites (Extended Search)

Enzyme Structure Provides Insights into Cancer and Aging Print Enzyme Structure Provides Insights into Cancer and Aging Print XPD helicase is an enzyme that unwinds the DNA double helix; it is one component of an essential repair mechanism that maintains the integrity of DNA. XPD is unique, however, in that pinpoint mutations of this single protein are responsible for three different human diseases: in xeroderma pigmentosum (XP), extreme sensitivity to sunlight promotes cancer; Cockayne syndrome (CS) involves stunted growth and premature aging; trichothiodystrophy (TTD), characterized by brittle hair and scaly skin, is another form of greatly accelerated aging. At the ALS, researchers from Berkeley Lab and The Scripps Research Institute recently solved the structure of XPD. The structure gives novel insight into the processes of aging and cancer by revealing how discrete flaws-as seemingly insignificant as a change in either of two adjacent amino acid residues-can lead to diseases with completely different physical manifestations.

468

Arsenic Cancer Risk Assessment: Recent Advances & Next Steps  

Science Conference Proceedings (OSTI)

In recent years, there has been an on-going debate on the appropriate regulatory approach for evaluating the carcinogenicity of inorganic arsenic compounds, specifically in the best methods and data sources for establishing a cancer potency, or cancer slope factor (CSF). The CSF is applied to the development of environmental standards, regulation and risk assessments under a variety of federal and state programs. Currently, the U.S. Environmental Protection Agency (EPA) continues to rely on chemical non-...

2011-12-30T23:59:59.000Z

469

Tanikawa C et al. Mol Cancer Res 8: 855-863, 2010. Tanikawa C et al. Cancer Res 69: 8761-9, 2009.  

E-Print Network (OSTI)

p53 p53 30000 p53 Tanikawa C et al. Mol Cancer Res 8: 855-863, 2010. Tanikawa C et al. Cancer Res 69: 8761-9, 2009. Tanikawa C et al.Oncogene 28: 3081-92, 2009. Morioka K et al. Cancer Science 100: 1227-1233, 2009. Kidokoro T et al. Oncogene 27: 1562-1571, 2008

Katsumoto, Shingo

470

What is the probability that radiation caused a particular cancer  

SciTech Connect

Courts, lawyers, health physicists, physicians, and others are searching for a credible answer to the question posed in the title of this paper. The cases in which the question arises frequently stem from an individual that has cancer and they, or their next-of-kin, are convinced that a past radiation exposure - usually small - is responsible for causing it. An arithmetic expression of this problem is simple: the probability of causation by the radiation dose in question is equal to the risk of cancer from the radiation dose divided by the risk of cancer from all causes. The application of risk factors to this equation is not so simple. It must involve careful evaluation of the reliability of and variations in risk coefficients for development of cancer due to radiation exposure, other carcinogenic agents, and natural causes for the particular individual. Examination of our knowledge of these various factors indicates that a large range in the answers can result due to the variability and imprecision of the data. Nevertheless, the attempts to calculate and the probability that radiation caused the cancer is extremely useful to provide a gross perspective on the probability of causation. It will likely rule in or out a significant number of cases despite the limitations in our understandings of the etiology of cancer and the risks from various factors. For the remaining cases, a thoughtful and educated judgment based on selected data and circumstances of the case will also be needed before the expert can develop and support his opinion.

Voelz, G.L.

1983-01-01T23:59:59.000Z

471

Carbon Ion Radiotherapy At Gunma University: Currently Indicated Cancer And Estimation Of Need  

SciTech Connect

Carbon ion radiotherapy for the first patient at Gunma University Heavy Ion Medical Center (GHMC) was initiated in March of 2010. The major specifications of the facility were determined based on the experience of clinical treatments at National Institute of Radiological Sciences (NIRS). The currently indicated sites of cancer treatment at GHMC are lung, prostate, head and neck, liver, rectum, bone and soft tissue. In order to evaluate the potential need for treatment in the region including Gunma prefecture and the adjacent 4 prefectures, an estimation model was constructed based on the Japanese cancer registration system, regular structure surveys by the Cancer Societies, and published articles on each cancer type. Carbon ion RT was potentially indicated for 8,085 patients and realistically for 1,527 patients, corresponding to 10% and 2% of the newly diagnosed cancer patients in the region. Prostate cancer (541 patients) followed by lung cancer (436 patients), and liver cancer (313 patients) were the most commonly diagnosed cancers.

Ohno, Tatsuya; Nakano, Takashi; Kanai, Tatsuaki; Yamada, Satoru [Gunma University Heavy Ion Medical Center, Gunma University, 3-39-22 Showa, Maebashi 371-8511 (Japan)

2011-06-01T23:59:59.000Z

472

Volumetric modulated arc radiotherapy for esophageal cancer  

SciTech Connect

A treatment planning study was performed to evaluate the performance of volumetric arc modulation with RapidArc (RA) against 3D conformal radiation therapy (3D-CRT) and conventional intensity-modulated radiation therapy (IMRT) techniques for esophageal cancer. Computed tomgraphy scans of 10 patients were included in the study. 3D-CRT, 4-field IMRT, and single-arc and double-arc RA plans were generated with the aim to spare organs at risk (OAR) and healthy tissue while enforcing highly conformal target coverage. The planning objective was to deliver 54 Gy to the planning target volume (PTV) in 30 fractions. Plans were evaluated based on target conformity and dose-volume histograms of organs at risk (lung, spinal cord, and heart). The monitor unit (MU) and treatment delivery time were also evaluated to measure the treatment efficiency. The IMRT plan improves target conformity and spares OAR when compared with 3D-CRT. Target conformity improved with RA plans compared with IMRT. The mean lung dose was similar in all techniques. However, RA plans showed a reduction in the volume of the lung irradiated at V{sub 20Gy} and V{sub 30Gy} dose levels (range, 4.62-17.98%) compared with IMRT plans. The mean dose and D{sub 35%} of heart for the RA plans were better than the IMRT by 0.5-5.8%. Mean V{sub 10Gy} and integral dose to healthy tissue were almost similar in all techniques. But RA plans resulted in a reduced low-level dose bath (15-20 Gy) in the range of 14-16% compared with IMRT plans. The average MU needed to deliver the prescribed dose by RA technique was reduced by 20-25% compared with IMRT technique. The preliminary study on RA for esophageal cancers showed improvements in sparing OAR and healthy tissue with reduced beam-on time, whereas only double-arc RA offered improved target coverage compared with IMRT and 3D-CRT plans.

Vivekanandan, Nagarajan, E-mail: viveknaren@hotmail.com [Department of Medical Physics, Cancer Institute, Chennai (India); Sriram, Padmanaban; Syam Kumar, S.A.; Bhuvaneswari, Narayanan; Saranya, Kamalakannan [Department of Medical Physics, Cancer Institute, Chennai (India)

2012-04-01T23:59:59.000Z

473

Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the Breast Cancer Association Consortium: a combined case-control study  

E-Print Network (OSTI)

7HT, UK. Breakthrough Breast Cancer Research Centre, TheInstitute of Cancer Research, 237 Fulman Road, London,control study. Breast Cancer Research 2010 12:R110. Submit

2010-01-01T23:59:59.000Z

474

East-West Symposium on nasopharyngeal cancer  

Science Conference Proceedings (OSTI)

Background: To achieve greater understanding of the epidemiology, pathogenesis, molecular oncology, diagnostic, and therapeutic aspects of nasopharyngeal cancer (NPC), an international meeting was held in June 2005, Toronto, Canada. Results: Further insights were obtained into the role of EBV in NPC development, with its diverse effects ranging from proliferative signals via NF-kB, to immunesuppression, to angiogenic gene regulation. Subsequently, multiple pathways are dysregulated in NPC as revealed by expression array analyses, including apoptosis, integrin, and B-catenin cascades. Advances have been made in the diagnosis and monitoring of NPC, using transoral brushings and plasma levels of EBV transcripts, which may not directly correlate with the number of circulating tumor cells, but is nevertheless informative in predicting and tracking disease response. Many novel therapies have promising results, particularly in the areas of immunotherapies, and the exploration of molecularly targeted approaches such as cetuximab or histone deacetylase inhibitors. Conclusions: The results from large randomized trials and meta-analyses have consistently demonstrated the benefit of concurrent chemotherapy with curative radiation therapy, but at a cost of greater acute and late-tissue toxicities. Further advances are required to achieve an improved understanding on the inter-relationship between environmental and genetic determinants in NPC development, to reduce the global burden of this disease. At the same time, novel therapeutic approaches are necessary to increase curability of NPC, but with reduced long-term toxicities.

Liu, F.-F. [Department of Radiation Oncology, Princess Margaret Hospital, University Health Network, Toronto (Canada) and Department of Radiation Oncology, University of Toronto, Toronto (Canada) and Division of Applied Molecular Oncology, Ontario Cancer Institute, Ontario (Canada) and Department of Medical Biophysics, University of Toronto, Toronto (Canada)]. E-mail: Fei-Fei.Liu@rmp.uhn.on.ca; Frappier, Lori [Department of Microbiology, University of Toronto, Toronto (Canada); Kim, John [Department of Radiation Oncology, Princess Margaret Hospital, University Health Network, Toronto (Canada); Department of Radiation Oncology, University of Toronto, Toronto (Canada); O'Sullivan, Brian [Department of Radiation Oncology, Princess Margaret Hospital, University Health Network, Toronto (Canada); Department of Radiation Oncology, University of Toronto, Toronto (Canada); Hui, Angela [Division of Applied Molecular Oncology, Ontario Cancer Institute, Ontario (Canada); Department of Medical Biophysics, University of Toronto, Toronto (Canada); Bastianutto, Carlo [Division of Applied Molecular Oncology, Ontario Cancer Institute, Ontario (Canada); Department of Medical Biophysics, University of Toronto, Toronto (Canada)

2007-03-01T23:59:59.000Z

475

Ozone, skin cancer, and the SST  

SciTech Connect

In 1971, the U.S. Congress cut off funding for development of supersonic transport aircraft prototypes when it was argued that the pollution created by SSTs could reduce the stratospheric ozone content and increase the incidence of skin cancer. At present, the theory of ozone depletion is in a rather uncertain state. Two examples of this are cited. First, ozone depletion may depend more on the availability of surfaces of aerosols and particles than on the content of chlorine. Second, it has been discovered that NO(x) can tie up active chlorine and thus reduce depletion from that source. We are therefore left with the paradoxical result that under certain circumstances SSTs flying in the lower stratospheric can actually counteract, at least partially, any ozone-depleting effects of CFCs. A recent study by scientists at the Brookhaven National Laboratory showed that melanoma rates would not be affected by changes in the ozone layer. If these results are confirmed, then much of the fear associated with ozone depletion disappears. It is difficult to tell how all this will affect a future supersonic transport program, since it is not clear whether a fleet of SSTs will increase or offset ozone depletion.

Singer, S.F.

1994-07-01T23:59:59.000Z

476

Modulation of the HGF/c-Met/Akt and p38 cell signaling pathways by 3,3'-diindolylmethane in MDA-MB-231 breast cancer cells  

E-Print Network (OSTI)

24 and perillyl alcohol. Cancer research 68: 7439-in breast cancer cells. Cancer research 66: 4952-4960. 49.through the Akt pathway. Cancer research 60: 6841-6845. 66.

Nicastro, Holly

2010-01-01T23:59:59.000Z

477

The prognostic significance of tumor cell detection in the peripheral blood versus the bone marrow in 733 early-stage breast cancer patients  

E-Print Network (OSTI)

American Association of Cancer Research Annual Meeting 2008cancer patients. Breast Cancer Research 2011 13:R61. SubmitMolloy et al. Breast Cancer Research 2011, 13:R61 http://

2011-01-01T23:59:59.000Z

478

BAC-FISH assays delineate complex chromosomal rearrangements in a case of post-Chernobyl childhood thyroid cancer  

E-Print Network (OSTI)

in a case of post-Chernobyl childhood thyroid cancer *D. Thyroid cancer after Chernobyl. Nature 1992;359:21-22. [LN. Thyroid cancer after Chernobyl. Nature [4] Gembicki M,

Kwan, Johnson

2010-01-01T23:59:59.000Z

479

An optimized five-gene multi-platform predictor of hormone receptor negative and triple negative breast cancer metastatic risk  

E-Print Network (OSTI)

5 Breakthrough Breast Cancer Research Unit, Guy’ s Hospital,metastatic risk. Breast Cancer Research 2013 15:R103. SubmitYau et al. Breast Cancer Research 2013, 15:R103 http://

2013-01-01T23:59:59.000Z

480

Cyclophosphamide- metabolizing enzyme polymorphisms and survival outcomes after adjuvant chemotherapy for node-positive breast cancer: a retrospective cohort study  

E-Print Network (OSTI)

cohort study Breast Cancer Research 2010, 12:R26How- Gor et al. Breast Cancer Research 2010, 12:R26 http://OS. Gor et al. Breast Cancer Research 2010, 12:R26 http://

2010-01-01T23:59:59.000Z

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481

Residential radon and lung cancer incidence in a Danish cohort  

SciTech Connect

High-level occupational radon exposure is an established risk factor for lung cancer. We assessed the long-term association between residential radon and lung cancer risk using a prospective Danish cohort using 57,053 persons recruited during 1993-1997. We followed each cohort member for cancer occurrence until 27 June 2006, identifying 589 lung cancer cases. We traced residential addresses from 1 January 1971 until 27 June 2006 and calculated radon at each of these addresses using information from central databases regarding geology and house construction. Cox proportional hazards models were used to estimate incidence rate ratios (IRR) and 95% confidence intervals (CI) for lung cancer risk associated with residential radon exposure with and without adjustment for sex, smoking variables, education, socio-economic status, occupation, body mass index, air pollution and consumption of fruit and alcohol. Potential effect modification by sex, traffic-related air pollution and environmental tobacco smoke was assessed. Median estimated radon was 35.8 Bq/m{sup 3}. The adjusted IRR for lung cancer was 1.04 (95% CI: 0.69-1.56) in association with a 100 Bq/m{sup 3} higher radon concentration and 1.67 (95% CI: 0.69-4.04) among non-smokers. We found no evidence of effect modification. We find a positive association between radon and lung cancer risk consistent with previous studies but the role of chance cannot be excluded as these associations were not statistically significant. Our results provide valuable information at the low-level radon dose range.

Braeuner, Elvira V., E-mail: ole@cancer.dk [Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen (Denmark); Danish Building Research Institute, Aalborg University (Denmark); Andersen, Claus E. [Center for Nuclear Technologies, Radiation Research Division, Riso National Laboratory for Sustainable Energy, Technical University of Denmark, Roskilde (Denmark)] [Center for Nuclear Technologies, Radiation Research Division, Riso National Laboratory for Sustainable Energy, Technical University of Denmark, Roskilde (Denmark); Sorensen, Mette [Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen (Denmark)] [Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen (Denmark); Jovanovic Andersen, Zorana [Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen (Denmark) [Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen (Denmark); Center for Epidemiology Screening, Department of Public Health, University of Copenhagen (Denmark); Gravesen, Peter [Geological Survey of Denmark and Greenland, Copenhagen (Denmark)] [Geological Survey of Denmark and Greenland, Copenhagen (Denmark); Ulbak, Kaare [National Institute of Radiation Protection, Herlev (Denmark)] [National Institute of Radiation Protection, Herlev (Denmark); Hertel, Ole [Department of Environmental Science, Aarhus University, Aarhus (Denmark)] [Department of Environmental Science, Aarhus University, Aarhus (Denmark); Pedersen, Camilla [Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen (Denmark)] [Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen (Denmark); Overvad, Kim [Department of Epidemiology, School of Public Health, Aarhus University, Aarhus (Denmark)] [Department of Epidemiology, School of Public Health, Aarhus University, Aarhus (Denmark); Tjonneland, Anne; Raaschou-Nielsen, Ole [Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen (Denmark)] [Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen (Denmark)

2012-10-15T23:59:59.000Z

482

Cancer and work in Canada with particular reference to occupational risk factors in breast cancer patients in one community and related selected research methods used to investigate those factors.  

E-Print Network (OSTI)

??Cancer represents a major cause of human morbidity and mortality. There is no scientific consensus regarding cancer causality or prevention. Occupational exposure potentially remains a… (more)

Brophy, James Thomas

2004-01-01T23:59:59.000Z

483

Approaches to the Spatial Modelling of Cancer Incidence and Mortality in Metropolitan Perth, Western Australia, 1990 -2005.  

E-Print Network (OSTI)

??Cancer is one of potentially preventable and treatable diseases. Cancer analysis from different perspectives is necessary to provide the information for health research and the… (more)

Shao, Changying

2011-01-01T23:59:59.000Z

484

How much is a health insurer willing to pay for colorectal cancer screening tests?  

Science Conference Proceedings (OSTI)

Colorectal Cancer (CRC) screening tests have proven to be cost-effective in preventing cancer incidence. Yet, as recent studies have shown, CRC screening tests are noticeably underutilized. Among the factors influencing CRC screening test utilization, ...

Reza Yaesoubi; Stephen D. Roberts

2008-12-01T23:59:59.000Z

485

APPLYING DATA MINING TECHNIQUES FOR CANCER CLASSIFICATION ON GENE EXPRESSION DATA  

Science Conference Proceedings (OSTI)

Cancer classification through gene expression data analysis has recently emerged as an active area of research. This paper applies Genetic Algorithms (GA) for selecting a group of relevant genes from cancer microarray data. Then, the popular classifiers, ...

Jinn-Yi Yeh

2008-08-01T23:59:59.000Z

486

Comparative Oncogenomic Analysis of Copy Number Alterations in Human and Zebrafish Tumors Enables Cancer Driver Discovery  

E-Print Network (OSTI)

The identification of cancer drivers is a major goal of current cancer research. Finding driver genes within large chromosomal events is especially challenging because such alterations encompass many genes. Previously, we ...

Zhang, GuangJun

487

Editorial Breast cancer stem cell markers- the rocky road to clinical  

E-Print Network (OSTI)

Lately, understanding the role of cancer stem cells in tumor initiation and progression became a major focus in stem cell biology and in cancer research. Considerable efforts, such as the recent studies by Honeth and colleagues, published in the June issue of Breast Cancer Research, are directed towards developing clinical applications of the cancer stem cell concepts. This work shows that the previously described CD44+CD24- stem cell phenotype is associated with basal-type breast cancers in human patients, in particular BRCA1 inherited cancers, but does not correlate with clinical outcome. These very interesting findings caution that the success of our efforts in translating cancer stem cell research into clinical practice depends on how thorough and rigorous we are at characterizing these cells. The cancer stem cell model, a concept initially proposed

Gabriela Dontu

2008-01-01T23:59:59.000Z

488

Comparative meta-analysis between human and mouse cancer microarray data reveals critical pathways  

Science Conference Proceedings (OSTI)

Identification of deregulated biomolecular pathways in cancer may be more important than identification of individual genes through differential expression. We have analysed data from 87 microarray datasets, spanning 25 different types of cancer, and ...

Pankaj Chopra; Jaewoo Kang; Seung-Mo Hong

2013-08-01T23:59:59.000Z

489

A general method for studying autocrine signaling and its impact on cancer cell growth  

E-Print Network (OSTI)

Autocrine signaling plays essential roles in providing self-sustaining growth signals to cancer cells. Since the introduction of the autocrine hypothesis in 1980s, the contribution of autocrine signaling in cancer medicine ...

Sampattavanich, Somponnat

2011-01-01T23:59:59.000Z

490

High-order chromatin architecture determines the landscape of chromosomal alterations in cancer  

E-Print Network (OSTI)

The accumulation of data on structural variation in cancer genomes provides an opportunity to better understand the mechanisms of genomic alterations and the forces of selection that act upon these alterations in cancer. ...

Fudenberg, Geoff

491

Mechanistic studies of Gemcitabine-loaded nanoplatforms in resistant pancreatic cancer cells  

E-Print Network (OSTI)

Background: Pancreatic cancer remains the deadliest of all cancers, with a mortality rate of 91%. Gemcitabine is considered the gold chemotherapeutic standard, but only marginally improves life-span due to its chemical ...

Papa, Anne-Laure

492

DOE Research Contributions to Radiation and Cancer Therapy  

NLE Websites -- All DOE Office Websites (Extended Search)

DOE Research Contributions to Radiation and Cancer Therapy Resources with Additional Information Planned radiation treatment Peregrine calculation from Mission Possible: DOE Advanced Biomedical Technology Research, page 10 Over the time span of many years, DOE's research has made many contributions to radiation and cancer therapy, including PEREGRINE and Boron Neutron Capture Therapy (BNCT). 'PEREGRINE, a hardware and software system that addresses the problem of radiation therapy dosage using fundamental physics principles, is a revolutionary new tool for analyzing and planning radiation treatment for cancer patients. About 90 percent of radiation treatment patients receive photon therapy, which is PEREGRINE's principal application. PEREGRINE may also be applied to the less frequently used electron-beam therapy and to brachytherapy, which is radiation therapy from an internally planted radiation source. It is effective for radiography, which predicts the pattern of radiation that is transmitted through a patient or other object.'1

493

Topo II: An Enzyme Target for Antibacterial and Cancer Drugs  

NLE Websites -- All DOE Office Websites (Extended Search)

Topo II: An Enzyme Target for Antibacterial and Cancer Drugs Print Topo II: An Enzyme Target for Antibacterial and Cancer Drugs Print The veil has finally been lifted on an enzyme that is critical to the process of DNA transcription and replication and is a prime target of antibacterial and anticancer drugs. Researchers at Berkeley Lab and the University of California, Berkeley, have produced the first three-dimensional structural images of a DNA-bound type II topoisomerase (topo II) that is responsible for untangling coiled strands of the chromosome during cell division. Preventing topo II from disentangling a cell's DNA is fatal to the cell, which is why drugs that target topo II serve as agents against bacterial infections and some forms of cancer. This first ever structural image of topo II should help in the development of future antibacterial and anticancer drugs that are even more effective and carry fewer potential side effects.

494

Enzyme Structure Provides Insights into Cancer and Aging  

NLE Websites -- All DOE Office Websites (Extended Search)

Bioscience Bioscience Enzyme Structure Provides Insights into Cancer and Aging Print XPD helicase is an enzyme that unwinds the DNA double helix; it is one component of an essential repair mechanism that maintains the integrity of DNA. XPD is unique, however, in that pinpoint mutations of this single protein are responsible for three different human diseases: in xeroderma pigmentosum (XP), extreme sensitivity to sunlight promotes cancer; Cockayne syndrome (CS) involves stunted growth and premature aging; trichothiodystrophy (TTD), characterized by brittle hair and scaly skin, is another form of greatly accelerated aging. At the ALS, researchers from Berkeley Lab and The Scripps Research Institute recently solved the structure of XPD. The structure gives novel insight into the processes of aging and cancer by revealing how discrete flaws-as seemingly insignificant as a change in either of two adjacent amino acid residues-can lead to diseases with completely different physical manifestations.

495

Topo II: An Enzyme Target for Antibacterial and Cancer Drugs  

NLE Websites -- All DOE Office Websites (Extended Search)

Topo II: An Enzyme Target for Antibacterial and Cancer Drugs Print Topo II: An Enzyme Target for Antibacterial and Cancer Drugs Print The veil has finally been lifted on an enzyme that is critical to the process of DNA transcription and replication and is a prime target of antibacterial and anticancer drugs. Researchers at Berkeley