National Library of Energy BETA

Sample records for incidents caus ing

  1. Incidents at nuclear power plants caused by the human factor

    SciTech Connect (OSTI)

    Mashin, V. A.

    2012-09-15

    Psychological analysis of the causes of incorrect actions by personnel is discussed as presented in the report 'Methodological guidelines for analyzing the causes of incidents in the operation of nuclear power plants.' The types of incorrect actions and classification of the root causes of errors by personnel are analyzed. Recommendations are made for improvements in the psychological analysis of causes of incorrect actions by personnel.

  2. Ing Arvid Nesheim | Open Energy Information

    Open Energy Info (EERE)

    Name: Ing Arvid Nesheim Address: Hoymyrmarka 123A Place: Vollen Zip: 1391 Region: Norway Sector: Marine and Hydrokinetic Phone Number: 47 951 08 439 Website: www.anwsite.com...

  3. Biography U. Dsterloh Degree: PD Dr.- Ing. habil. Institution...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    U. Dsterloh Degree: PD Dr.- Ing. habil. Institution: Clausthal University of Technology. Chair: chair for waste disposal technologies and geomechanics. 1982- 1988 field of study:...

  4. Anatomy of an incident

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Cournoyer, Michael E.; Trujillo, Stanley; Lawton, Cindy M.; Land, Whitney M.; Schreiber, Stephen B.

    2016-03-23

    A traditional view of incidents is that they are caused by shortcomings in human competence, attention, or attitude. It may be under the label of “loss of situational awareness,” procedure “violation,” or “poor” management. A different view is that human error is not the cause of failure, but a symptom of failure – trouble deeper inside the system. In this perspective, human error is not the conclusion, but rather the starting point of investigations. During an investigation, three types of information are gathered: physical, documentary, and human (recall/experience). Through the causal analysis process, apparent cause or apparent causes are identifiedmore » as the most probable cause or causes of an incident or condition that management has the control to fix and for which effective recommendations for corrective actions can be generated. A causal analysis identifies relevant human performance factors. In the following presentation, the anatomy of a radiological incident is discussed, and one case study is presented. We analyzed the contributing factors that caused a radiological incident. When underlying conditions, decisions, actions, and inactions that contribute to the incident are identified. This includes weaknesses that may warrant improvements that tolerate error. Measures that reduce consequences or likelihood of recurrence are discussed.« less

  5. Q&A: FORGE-ing Ahead to Clean, Low-Cost Geothermal Energy | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy FORGE-ing Ahead to Clean, Low-Cost Geothermal Energy Q&A: FORGE-ing Ahead to Clean, Low-Cost Geothermal Energy July 17, 2014 - 2:48pm Addthis Q&A: FORGE-ing Ahead to Clean, Low-Cost Geothermal Energy Q&A: FORGE-ing Ahead to Clean, Low-Cost Geothermal Energy Q&A: FORGE-ing Ahead to Clean, Low-Cost Geothermal Energy Q&A: FORGE-ing Ahead to Clean, Low-Cost Geothermal Energy Lauren Boyd Lauren Boyd Program Manager, Enhanced Geothermal Systems (EGS) Benjamin Phillips

  6. ENERGISE-ing Solutions to Scale Up Distributed Solar | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ENERGISE-ing Solutions to Scale Up Distributed Solar ENERGISE-ing Solutions to Scale Up Distributed Solar May 31, 2016 - 4:10pm Addthis ENERGISE-ing Solutions to Scale Up Distributed Solar Guohui Yuan Systems Integration Program Manager, SunShot Initiative Learn more about ENERGISE If a utility pole falls in a forest and no energy company employee is around to hear it, does it make a sound? Currently, the answer is no. For the most part, utility companies rely on customer calls to react to

  7. Biography U. Düsterloh Degree: PD Dr.- Ing. habil. Institution: Clausthal University of Technology.

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    U. Düsterloh Degree: PD Dr.- Ing. habil. Institution: Clausthal University of Technology. Chair: chair for waste disposal technologies and geomechanics. 1982- 1988 field of study: mining engineer 1989- 1993 PhD work - geomechanical investigations on the stability of salt caverns for waste disposal. 2009 Habilitation - proof of stability and integrity of underground excavations in saliniferous formations with special regard to lab tests. 1989 - 2012 chief engineer at Clausthal University of

  8. Incidents of Security Concern

    SciTech Connect (OSTI)

    Atencio, Julian J.

    2014-05-01

    This presentation addresses incidents of security concern and an incident program for addressing them. It addresses the phases of an inquiry, and it divides incidents into categories based on severity and interest types based on whether security, management, or procedural interests are involved. A few scenarios are then analyzed according to these breakdowns.

  9. July 2013 Cyber Incident

    Broader source: Energy.gov [DOE]

    The Department of Energy (DOE) has confirmed a cyber incident that occurred at the end of July and resulted in the unauthorized disclosure of federal employee Personally Identifiable Information ...

  10. January 2013 Cyber Incident

    Broader source: Energy.gov [DOE]

    The Department of Energy (DOE) has confirmed a recent cyber incident that occurred in mid-January 2013 which targeted the Headquarters' network and resulted in the unauthorized disclosure of...

  11. Incidents of Security Concern

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2004-03-17

    Sets forth requirements for the DOE Incidents of Security Concern Program, including timely identification and notification of, response to, inquiry into, reporting of, and closure actions for incidents of security concern. Cancels Chapter VII of DOE O 470.1; DOE N 471.3; and Chapter IV of DOE M 471.2-1B (Note: Paragraphs 1 and 2 of Chapter III remain in effect.) Canceled by DOE O 470.4.

  12. Incident Management | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Management Incident Management IC2 (004).jpg The Incident Management Program (IMP) focuses on: threat information sharing critical infrastructure protection active defense incident preparedness. The IMP reports all incidents to the United States Computer Emergency Readiness Team (US-CERT), fulfilling statutory requirements and ensuring a coordinated response to cyber attacks. Joint Cybersecurity Coordination Center (JC3) The Joint Cybersecurity Coordination Center (JC3) provides DOE with

  13. Cyber Security Incident Management Manual

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2009-01-08

    The manual establishes minimum requirements for a structured cyber security incident detection and management process for detecting, identifying, categorizing, containing, reporting, and mitigating cyber security incidents involving DOE information and information systems operated by DOE or by contractors on behalf of the Department. No cancellations. Admin Chg 1 dated 9-1-09.

  14. Cyber Security Incident Management Manual

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2009-01-08

    The manual establishes minimum requirements for a structured cyber security incident detection and management process for detecting, identifying, categorizing, containing, reporting, and mitigating cyber security incidents involving DOE information and information systems operated by DOE or by contractors on behalf of the Department. No cancellations.

  15. Reporting Incidents Of Security Concern

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2001-04-03

    To enhance the Department of Energy (DOE) Incidents of Security Concern Reporting Program through more consistent reporting, better information tracking, and interactive coordination. DOE N 251.54, dated 07/08/03, extends this directive until 07/08/04. Cancels Deputy Secretary Glauthier memorandum, subject: Reporting Security Incidents, dated 9-7-99.

  16. Cyber Security Incident Management Manual

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2009-01-08

    The manual establishes minimum requirements for a structured cyber security incident detection and management process for detecting, identifying, categorizing, containing, reporting, and mitigating cyber security incidents involving DOE information and information systems operated by DOE or by contractors on behalf of the Department. Admin Chg 1 dated 9-1-09; Admin Chg 2 dated 12-22-09. Canceled by DOE O 205.1B.

  17. LANL responds to radiological incident

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    LANL responds to radiological incident LANL responds to radiological incident Multiple tests indicate no health risks to public or employees. August 27, 2012 Aerial view of the Los Alamos Neutron Science Center(LANSCE). Aerial view of the Los Alamos Neutron Science Center (LANSCE). The contamination poses no danger to the public. The Laboratory is investigating the inadvertent spread of Technetium 99 by employees and contractors at the Lujan Neutron Scattering Center August 27, 2012-The

  18. Material development in the SI sub 3 N sub 4 system using glass encapsulated Hip'ing

    SciTech Connect (OSTI)

    Corbin, N.D.; Sundberg, G.J.; Siebein, K.N.; Willkens, C.A.; Pujari, V.K.; Rossi, G.A.; Hansen, J.S.; Chang, C.L.; Hammarstrom, J.L.

    1992-04-01

    This report covers a two-year program to develop fully dense Si{sub 3}N{sub 4} matrix SiC whisker composites with enhanced properties over monolithic Si{sub 3}N{sub 4} materials. The primary goal was to develop a composite with a fracture toughness > 10 MPa{radical}m, capable of using high pressure glass encapsulated HIP'ing. Coating methods were developed to apply thin (<150nm) stoichiometric BN layers to SiC whiskers and also to apply a dual coating of SiC over carbon to the whiskers. Fracture toughness of the composites was determined to increase as the quantity of whiskers (or elongated grains) with their axis perpendicular to the crack plane increased. Of the interface compositions evaluated in this effort, carbon was determined to be the most effective for increasing toughness. The highest toughnesses (6.8--7.0 MPa{radical}m) were obtained with uniaxially aligned carbon coated whiskers. There was no evidence of the carbon coating compromising the oxidation resistance of the composites at 1370{degree}C.

  19. Cyber Incidents Involving Control Systems

    SciTech Connect (OSTI)

    Robert J. Turk

    2005-10-01

    The Analysis Function of the US-CERT Control Systems Security Center (CSSC) at the Idaho National Laboratory (INL) has prepared this report to document cyber security incidents for use by the CSSC. The description and analysis of incidents reported herein support three CSSC tasks: establishing a business case; increasing security awareness and private and corporate participation related to enhanced cyber security of control systems; and providing informational material to support model development and prioritize activities for CSSC. The stated mission of CSSC is to reduce vulnerability of critical infrastructure to cyber attack on control systems. As stated in the Incident Management Tool Requirements (August 2005) ''Vulnerability reduction is promoted by risk analysis that tracks actual risk, emphasizes high risk, determines risk reduction as a function of countermeasures, tracks increase of risk due to external influence, and measures success of the vulnerability reduction program''. Process control and Supervisory Control and Data Acquisition (SCADA) systems, with their reliance on proprietary networks and hardware, have long been considered immune to the network attacks that have wreaked so much havoc on corporate information systems. New research indicates this confidence is misplaced--the move to open standards such as Ethernet, Transmission Control Protocol/Internet Protocol, and Web technologies is allowing hackers to take advantage of the control industry's unawareness. Much of the available information about cyber incidents represents a characterization as opposed to an analysis of events. The lack of good analyses reflects an overall weakness in reporting requirements as well as the fact that to date there have been very few serious cyber attacks on control systems. Most companies prefer not to share cyber attack incident data because of potential financial repercussions. Uniform reporting requirements will do much to make this information available to

  20. ORISE: The Medical Aspects of Radiation Incidents

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The Medical Aspects of Radiation Incidents The Medical Aspects of Radiation Incidents provides the basic information needed for the medical management of victims of radiation ...

  1. Chemical incident economic impact analysis methodology. (Technical...

    Office of Scientific and Technical Information (OSTI)

    Chemical incident economic impact analysis methodology. Citation Details In-Document Search Title: Chemical incident economic impact analysis methodology. You are accessing a ...

  2. Nuclear Incident Team | National Nuclear Security Administration...

    National Nuclear Security Administration (NNSA)

    Incident Team NNSA houses the Nuclear Incident Team (NIT), which is responsible for deploying assets at the request of coordinating agencies in response to a nuclear or ...

  3. INCIDENT REPORTING: LEARNING FROM EXPERIENCE

    SciTech Connect (OSTI)

    Weiner, Steven C.; Kinzey, Bruce R.; Dean, Jesse D.; Davis, Patrick B.; Ruiz, Antonio

    2007-09-12

    Experience makes a superior teacher. Sharing the details surrounding safety events is one of the best ways to help prevent their recurrence elsewhere. This approach requires an open, non-punitive environment to achieve broad benefits. The Hydrogen Incident Reporting Tool (www.h2incidents.org) is intended to facilitate the sharing of lessons learned and other relevant information gained from actual experiences using and working with hydrogen and hydrogen systems. Its intended audience includes those involved in virtually any aspect of hydrogen technology, systems and use, with an emphasis towards energy and transportation applications. The database contains records of safety events both publicly available and/or voluntarily submitted. Typical records contain a general description of the occurrence, contributing factors, equipment involved, and some detailing of consequences and changes that have been subsequently implemented to prevent recurrence of similar events in the future. The voluntary and confidential nature and other characteristics surrounding the database mean that any analysis of apparent trends in its contents cannot be considered statistically valid for a universal population. A large portion of reported incidents have occurred in a laboratory setting due to the typical background of the reporting projects, for example. Yet some interesting trends are becoming apparent even at this early stage of the database’s existence and general lessons can already be taken away from these experiences. This paper discusses the database and a few trends that have already become apparent for the reported incidents. Anticipated future uses of this information are also described. This paper is intended to encourage wider participation and usage of the incidents reporting database and to promote the safety benefits offered by its contents.

  4. Chapter_11_Incidents_of_Security_Concern

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    1 Incidents of Security Concern This chapter covers the DOE HQ implementation of DOE Order 470.4B, Safeguards and Security Program, Attachment 5, Incidents of Security Concern. AU-42 manages the HQ Security Incidents Program. Incidents of Security Concern (henceforth referred to as Incidents) are actions, inactions, or events that are believed to: * Pose threats to national security interests and/or DOE assets * Create potentially serious or dangerous security situations * Significantly affect

  5. JC3 Incident Reporting | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Management » JC3 Incident Reporting JC3 Incident Reporting technology-785742_960_720.jpg JC3 Incident Reporting Procedures U.S. Department of Energy Facilities/Contractors Only DOE O 205.1-B Chg 2 4.(c)(13) DEPARTMENT OF ENERGY CYBER SECURITY PROGRAM requires a defined "process for incident reporting that requires all cyber security incidents involving information or information systems, including privacy breaches, under DOE or DOE contractor control must be identified, mitigated,

  6. Effect of Emergency Argon on FCF Operational Incidents

    SciTech Connect (OSTI)

    Charles Solbrig

    2011-12-01

    The following report presents analyses of operational incidents which are considered in the safety analysis of the FCF argon cell and the effect that the operability of the emergency argon system has on the course of these incidents. The purpose of this study is to determine if the emergency argon system makes a significant difference in ameliorating the course of these incidents. Six incidents were considered. The following three incidents were analyzed. These are: 1. Cooling failing on 2. Vacuum Pump Failing on 3. Argon Supplies Failing on. In the remaining three incidents, the emergency argon supply would have no effect on the course of these transients since it would not come on during these incidents. The transients are 1. Loss of Cooling 2. Loss of power (Differs from above by startup delay till the Diesel Generators come on.) 3. Cell rupture due to an earthquake or other cause. The analyses of the first three incidents are reported on in the next three sections. This report is issued realizing the control parameters used may not be optimum, and additional modeling must be done to model the inertia of refrigeration system, but the major conclusion concerning the need for the emergency argon system is still valid. The timing of some events may change with a more accurate model but the differences between the transients with and without emergency argon will remain the same. Some of the parameters assumed in the analyses are Makeup argon supply, 18 cfm, initiates when pressure is = -6 iwg., shuts off when pressure is = -3.1 iwg. 170,000 ft3 supply. Min 1/7th always available, can be cross connected to HFEF argon supply dewar. Emergency argon supply, 900 cfm, initiates when pressure is = -8 iwg. shuts off when pressure is =-4 iwg. reservoir 220 ft3, refilled when tank farm pressure reduces to 1050 psi which is about 110 ft3.

  7. Nuclear Incident Team | National Nuclear Security Administration

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Apply for Our Jobs Our Jobs Working at NNSA Blog Home Nuclear Incident Team Nuclear Incident Team Fukushima: Five Years Later After the March 11, 2011, Japan earthquake, tsunami, ...

  8. ORISE: Incident Command System (ICS) Training

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Incident Command System (ICS) Training The Oak Ridge Institute for Science and Education (ORISE) supports the emergency response community by promoting interagency cooperation and...

  9. Researchers correlate incidences of rheumatoid arthritis and...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Researchers correlate incidences of rheumatoid arthritis and giant cell arteritis with solar cycles By John Greenwald June 15, 2015 Tweet Widget Google Plus One Share on Facebook A ...

  10. Advanced Techniques for Root Cause Analysis

    Energy Science and Technology Software Center (OSTI)

    2000-09-19

    Five items make up this package, or can be used individually. The Chronological Safety Management Template utilizes a linear adaptation of the Integrated Safety Management System laid out in the form of a template that greatly enhances the ability of the analyst to perform the first step of any investigation which is to gather all pertinent facts and identify causal factors. The Problem Analysis Tree is a simple three (3) level problem analysis tree whichmore » is easier for organizations outside of WSRC to use. Another part is the Systemic Root Cause Tree. One of the most basic and unique features of Expanded Root Cause Analysis is the Systemic Root Cause portion of the Expanded Root Cause Pyramid. The Systemic Root Causes are even more basic than the Programmatic Root Causes and represent Root Causes that cut across multiple (if not all) programs in an organization. the Systemic Root Cause portion contains 51 causes embedded at the bottom level of a three level Systemic Root Cause Tree that is divided into logical, organizationally based categorie to assist the analyst. The Computer Aided Root Cause Analysis that allows the analyst at each level of the Pyramid to a) obtain a brief description of the cause that is being considered, b) record a decision that the item is applicable, c) proceed to the next level of the Pyramid to see only those items at the next level of the tree that are relevant to the particular cause that has been chosen, and d) at the end of the process automatically print out a summary report of the incident, the causal factors as they relate to the safety management system, the probable causes, apparent causes, Programmatic Root Causes and Systemic Root Causes for each causal factor and the associated corrective action.« less

  11. Incident Prevention, Warning, and Response (IPWAR) Manual

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2004-09-30

    This Manual defines a structured, cohesive, and consistent process for performing incident prevention, warning, and response for DOE's Federal information systems and is consistent with the requirements of Federal laws, Executive orders, national security directives, and other regulations. The Manual also provides requirements and implementation instructions for the Department's Incident Prevention, Warning and Response process, and supplements DOE O 205.1, Department of Energy Cyber Security Management Program, dated 3-21-03. DOE N 205.17 cancels this manual. This manual cancels DOE N 205.4, Handling Cyber Security Alerts and Advisories and Reporting Cyber Security Incidents, dated 3/18/2002.

  12. Establishing and operating an incident response team

    SciTech Connect (OSTI)

    Padgett, K.M.

    1992-01-01

    Occurrences of improprieties dealing with computer usage are on the increase. They range all the way from misuse by employees to international computer telecommunications hacking. In addition, natural disasters and other disasters such as catastrophic fires may also fall into the same category. These incidents, like any other breach of acceptable behavior, may or may not involve actual law breaking. A computer incident response team should be created as a first priority. This report discusses the establishment and operation of a response team.

  13. Establishing and operating an incident response team

    SciTech Connect (OSTI)

    Padgett, K.M.

    1992-09-01

    Occurrences of improprieties dealing with computer usage are on the increase. They range all the way from misuse by employees to international computer telecommunications hacking. In addition, natural disasters and other disasters such as catastrophic fires may also fall into the same category. These incidents, like any other breach of acceptable behavior, may or may not involve actual law breaking. A computer incident response team should be created as a first priority. This report discusses the establishment and operation of a response team.

  14. ARM - Human Causes

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Study Hall About ARM Global Warming FAQ Just for Fun Meet our Friends Cool Sites Teachers Teachers' Toolbox Lesson Plans Human Causes Some of the human activities which can cause ...

  15. Root cause outline

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    14 Signature page ... Error Bookmark not defined. Appendix A Capital Allocation Board Quarterly Status Reports Appendix B Root Cause Analysis...

  16. STEM-ing the Tide

    Broader source: Energy.gov [DOE]

    The MacArthur Foundation rolled out its latest class of “geniuses” – 23 Americans who stand out because of their creativity and enterprise.

  17. Challenges for Early Responders to a Nuclear / Radiological Terrorism Incident

    SciTech Connect (OSTI)

    Wells, M.A.; Stearns, L.J.; Davie, A.D.; Day, E.

    2007-07-01

    Even in the best of circumstances, most municipalities would face severe challenges in providing effective incident response to a large scale radiation release caused by nuclear terrorism or accident. Compounding obvious complexities, the effectiveness of first and early responders to a radiological emergency may also be hampered by an insufficient distribution of radiation detection and monitoring equipment, local policies concerning triage and field decontamination of critical victims, malfunctioning communications, inadequate inter-agency agility, and the psychological 'fear' impact on early responders. This paper examines several issues impeding the early response to nuclear terrorism incidents with specific consideration given to the on-going and forward-thinking preparedness efforts currently being developed in the Sacramento, California region. Specific recommendations are provided addressing hot zone protocols, radiation detection and monitoring equipment, hasty patient packaging techniques, vertically and horizontally integrated pre-event training, mitigating psychological fear, and protocols for the effective 'hand-off' from first responders to subsequent early response-recovery teams. (authors)

  18. Investigation of excess thyroid cancer incidence in Los Alamos County

    SciTech Connect (OSTI)

    Athas, W.F.

    1996-04-01

    Los Alamos County (LAC) is home to the Los Alamos National Laboratory, a U.S. Department of Energy (DOE) nuclear research and design facility. In 1991, the DOE funded the New Mexico Department of Health to conduct a review of cancer incidence rates in LAC in response to citizen concerns over what was perceived as a large excess of brain tumors and a possible relationship to radiological contaminants from the Laboratory. The study found no unusual or alarming pattern in the incidence of brain cancer, however, a fourfold excess of thyroid cancer was observed during the late-1980`s. A rapid review of the medical records for cases diagnosed between 1986 and 1990 failed to demonstrate that the thyroid cancer excess had resulted from enhanced detection. Surveillance activities subsequently undertaken to monitor the trend revealed that the excess persisted into 1993. A feasibility assessment of further studies was made, and ultimately, an investigation was conducted to document the epidemiologic characteristics of the excess in detail and to explore possible causes through a case-series records review. Findings from the investigation are the subject of this report.

  19. Electrically floating, near vertical incidence, skywave antenna

    DOE Patents [OSTI]

    Anderson, Allen A.; Kaser, Timothy G.; Tremblay, Paul A.; Mays, Belva L.

    2014-07-08

    An Electrically Floating, Near Vertical Incidence, Skywave (NVIS) Antenna comprising an antenna element, a floating ground element, and a grounding element. At least part of said floating ground element is positioned between said antenna element and said grounding element. The antenna is separated from the floating ground element and the grounding element by one or more electrical insulators. The floating ground element is separated from said antenna and said grounding element by one or more electrical insulators.

  20. A common language for computer security incidents

    SciTech Connect (OSTI)

    John D. Howard; Thomas A Longstaff

    1998-10-01

    Much of the computer security information regularly gathered and disseminated by individuals and organizations cannot currently be combined or compared because a common language has yet to emerge in the field of computer security. A common language consists of terms and taxonomies (principles of classification) which enable the gathering, exchange and comparison of information. This paper presents the results of a project to develop such a common language for computer security incidents. This project results from cooperation between the Security and Networking Research Group at the Sandia National Laboratories, Livermore, CA, and the CERT{reg_sign} Coordination Center at Carnegie Mellon University, Pittsburgh, PA. This Common Language Project was not an effort to develop a comprehensive dictionary of terms used in the field of computer security. Instead, the authors developed a minimum set of high-level terms, along with a structure indicating their relationship (a taxonomy), which can be used to classify and understand computer security incident information. They hope these high-level terms and their structure will gain wide acceptance, be useful, and most importantly, enable the exchange and comparison of computer security incident information. They anticipate, however, that individuals and organizations will continue to use their own terms, which may be more specific both in meaning and use. They designed the common language to enable these lower-level terms to be classified within the common language structure.

  1. Summary of canister overheating incident at the Carbon Tetrachloride Expedited Response Action site

    SciTech Connect (OSTI)

    Driggers, S.A.

    1994-03-10

    The granular activated carbon (GAC)-filled canister that overheated was being used to adsorb carbon tetrachloride vapors drawn from a well near the 216-Z-9 Trench, a subsurface disposal site in the 200 West Area of the Hanford Site. The overheating incident resulted in a band of discolored paint on the exterior surface of the canister. Although there was no other known damage to equipment, no injuries to operating personnel, and no releases of hazardous materials, the incident is of concern because it was not anticipated. It also poses the possibility of release of carbon tetrachloride and other hazardous vapors if the incident were to recur. All soil vapor extraction system (VES) operations were halted until a better understanding of the cause of the incident could be determined and controls implemented to reduce the possibility of a recurrence. The focus of this report and the intent of all the activities associated with understanding the overheating incident has been to provide information that will allow safe restart of the VES operations, develop operational limits and controls to prevent recurrence of an overheating incident, and safely optimize recovery of carbon tetrachloride from the ground.

  2. An Incident Management Preparedness and Coordination Toolkit

    SciTech Connect (OSTI)

    Koch, Daniel B; Payne, Patricia W

    2012-01-01

    Although the use of Geographic Information Systems (GIS) by centrally-located operations staff is well established in the area of emergency response, utilization by first responders in the field is uneven. Cost, complexity, and connectivity are often the deciding factors preventing wider adoption. For the past several years, Oak Ridge National Laboratory (ORNL) has been developing a mobile GIS solution using free and open-source software targeting the needs of front-line personnel. Termed IMPACT, for Incident Management Preparedness and Coordination Toolkit, this ORNL application can complement existing GIS infrastructure and extend its power and capabilities to responders first on the scene of a natural or man-made disaster.

  3. Carbon-initiated effluent tank overpressure incident

    SciTech Connect (OSTI)

    Sherman, R.E.; Crawford, K.C.; Cusick, T.M.; Csengery, L.V.

    1996-12-31

    This report provides, for information purposes, a description of an unusual event and the corrective actions undertaken by the Shell facility involved. Shell and the authors hope that this information will help personnel associated with other facilities understand a non-obvious failure mechanism and take action to prevent their experiencing similar incidents. While drawn from actual experience, the information provided should be considered illustrative. Each company should be considered illustrative. Each company should review their own facilities, materials or processes to determine the appropriate equipment and procedures for their own specific circumstances.

  4. Channeling Doping Profiles Studies for Small Incident Angle Implantation into Silicon Wafers

    SciTech Connect (OSTI)

    Guo, B.N.; Variam, N.; Jeong, U.; Mehta, S.; Posselt, M.; Lebedev, A.

    2003-08-26

    Traditional de-channeling dopant profiles in the silicon crystal wafers have been achieved by tilting the wafer away from the incident beam. As feature sizes of device shrink, the advantages for channeled doping profiles for implants with small or near zero degree incident angles are being recognized. For example, high-energy CMOS well spacing limitations caused by shadowing and encroachment of the ion beam by photoresist mask can be avoided for near zero degree incident implants. Accurate models of channeled profiles are essential to predict the device performance. This paper mainly discusses the damage effect on channeled dopant profiles. Especially, damage effects on channeled dopant profiles are correlated to ThermaWave (TW) measurements. It is demonstrated that there is a critical dose at which the damage effects have to be considered for channeled dopant profile evolvements.

  5. Personnel Accountability for Non-COOP Incidents | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Personnel Accountability for Non-COOP Incidents Personnel Accountability for Non-COOP Incidents This document establishes reporting requirements for non-COOP incidents. Personnel Accountability for Non-COOP Incidents (1.26 MB) Responsible Contacts Bruce Murray HR Policy Advisor E-mail bruce.murray@hq.doe.gov Phone 202-586-3372 More Documents & Publications Inspection Report: IG-0784 Audit Report: IG-0845 Fiscal Year 2013 Department of Energy Annual Occupational Safety and Health Report for

  6. Nuclear Incident Team | National Nuclear Security Administration | (NNSA)

    National Nuclear Security Administration (NNSA)

    Incident Team NNSA houses the Nuclear Incident Team (NIT), which is responsible for deploying assets at the request of coordinating agencies in response to a nuclear or radiological incident. The NIT's mission is to coordinate NNSA assets for deployment, continually monitor deployment activities, and provide situational awareness of activities to NNSA management. The NIT is staffed and fully operational within two hours of notification

  7. Implementation of the National Incident Management System (NIMS)/Incident Command System (ICS) in the Federal Radiological Monitoring and Assessment Center(FRMAC) - Emergency Phase

    SciTech Connect (OSTI)

    NSTec Environmental Restoration

    2007-04-01

    Homeland Security Presidential Directive HSPD-5 requires all federal departments and agencies to adopt a National Incident Management System (NIMS)/Incident Command System (ICS) and use it in their individual domestic incident management and emergency prevention, preparedness, response, recovery, and mitigation programs and activities, as well as in support of those actions taken to assist state and local entities. This system provides a consistent nationwide template to enable federal, state, local, and tribal governments, private-sector, and nongovernmental organizations to work together effectively and efficiently to prepare for, prevent, respond to, and recover from domestic incidents, regardless of cause, size, or complexity, including acts of catastrophic terrorism. This document identifies the operational concepts of the Federal Radiological Monitoring and Assessment Center's (FRMAC) implementation of the NIMS/ICS response structure under the National Response Plan (NRP). The construct identified here defines the basic response template to be tailored to the incident-specific response requirements. FRMAC's mission to facilitate interagency environmental data management, monitoring, sampling, analysis, and assessment and link this information to the planning and decision staff clearly places the FRMAC in the Planning Section. FRMAC is not a mitigating resource for radiological contamination but is present to conduct radiological impact assessment for public dose avoidance. Field monitoring is a fact-finding mission to support this effort directly. Decisions based on the assessed data will drive public protection and operational requirements. This organizational structure under NIMS is focused by the mission responsibilities and interface requirements following the premise to provide emergency responders with a flexible yet standardized structure for incident response activities. The coordination responsibilities outlined in the NRP are based on the NIMS

  8. Recovery from chemical, biological, and radiological incidents :

    SciTech Connect (OSTI)

    Franco, David Oliver; Yang, Lynn I.; Hammer, Ann E.

    2012-06-01

    To restore regional lifeline services and economic activity as quickly as possible after a chemical, biological or radiological incident, emergency planners and managers will need to prioritize critical infrastructure across many sectors for restoration. In parallel, state and local governments will need to identify and implement measures to promote reoccupation and economy recovery in the region. This document provides guidance on predisaster planning for two of the National Disaster Recovery Framework Recovery Support Functions: Infrastructure Systems and Economic Recovery. It identifies key considerations for infrastructure restoration, outlines a process for prioritizing critical infrastructure for restoration, and identifies critical considerations for promoting regional economic recovery following a widearea disaster. Its goal is to equip members of the emergency preparedness community to systematically prioritize critical infrastructure for restoration, and to develop effective economic recovery plans in preparation for a widearea CBR disaster.

  9. Security incidents on the Internet, 1989--1995

    SciTech Connect (OSTI)

    Howard, J.D.

    1995-12-31

    This paper presents an analysis of trends in Internet security based on an investigation of 4,299 Internet security-related incidents reported to the CERT{reg_sign} Coordination Center (CERT{reg_sign}/CC) from 1989 through 1995. Prior to this research, knowledge of actual Internet security incidents was limited and primarily anecdotal. This research: (1) developed a taxonomy to classify Internet attacks and incidents, (2) organized, classified, and analyzed CERT{reg_sign}/CC incident records, (3) summarized the relative frequency of the use of tools and vulnerabilities, success in achieving access, and results of attacks, (4) estimated total Internet incident activity, (5) developed recommendations for Internet users and suppliers, and (6) developed recommendations for future research. With the exception of denial-of-service attacks, security incidents were found to be increasing at a rate less than Internet growth. Estimates showed that most, if not all, severe incidents were reported to the CERT{reg_sign}/CC, and that more than one out of three above average incidents (in terms of duration and number of sites) were reported. Estimates also indicated that a typical Internet site was involved in, at most, around one incident (of any kind) per year, and a typical Internet host in, at most, around one incident in 45 years. The probability of unauthorized privileged access was around an order of magnitude less likely. As a result, simple and reasonable security precautions should be sufficient for most Internet users.

  10. Computerized Accident Incident Reporting System | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Computerized Accident Incident Reporting System Computerized Accident Incident Reporting System CAIRS Database The Computerized Accident/Incident Reporting System is a database used to collect and analyze DOE and DOE contractor reports of injuries, illnesses, and other accidents that occur during DOE operations. CAIRS is a Government computer system and, as such, has security requirements that must be followed. Access to the database is open to DOE and DOE contractors. Additional information

  11. NNSA Nuclear/Radiological Incident Response | National Nuclear...

    National Nuclear Security Administration (NNSA)

    NNSA NuclearRadiological Incident Response December 01, 2008 The National Nuclear Security Administration (NNSA) has over 60 years of nuclear weapons experience in responding to ...

  12. ORISE: DeepwaterHorizon and Nuclear & Radiological Incidents

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    System's Incident Command System was utilized during the response, there were immense command and coordination challenges for the unified management team never before...

  13. Source term estimation during incident response to severe nuclear...

    Office of Scientific and Technical Information (OSTI)

    response to severe nuclear power plant accidents Citation Details In-Document Search Title: Source term estimation during incident response to severe nuclear power plant ...

  14. Headquarters Facilities Master Security Plan - Chapter 11, Incidents...

    Office of Environmental Management (EM)

    Security Plan - Chapter 11, Incidents of Security Concern Whenever a failure to properly protect classified matter is detected, it must be formally reported and investigated. ...

  15. Model Recovery Procedure for Response to a Radiological Transportation Incident

    Broader source: Energy.gov [DOE]

    This Transportation Emergency Preparedness Program (TEPP) Model Recovery Procedure contains the recommended elements for developing and conducting recovery planning at transportation incident scene...

  16. Laser Incident Lessons Learned and Action List (Technical Report...

    Office of Scientific and Technical Information (OSTI)

    Laser Incident Lessons Learned and Action List Citation Details In-Document Search Title: ... output into two work areas in which qualified operators conduct research experiments. ...

  17. Laser Incident Lessons Learned and Action List (Technical Report...

    Office of Scientific and Technical Information (OSTI)

    Title: Laser Incident Lessons Learned and Action List You are accessing a document from ... output into two work areas in which qualified operators conduct research experiments. ...

  18. SU-C-BRD-05: Implementation of Incident Learning in the Safety and Quality Management of Radiotherapy: The Primary Experience in a New Established Program with Advanced Techniques

    SciTech Connect (OSTI)

    Yang, R; Wang, J

    2014-06-15

    Purpose: To explore the implementation and effectiveness of incident learning for the safety and quality of radiotherapy in a new established radiotherapy program with advanced technology. Methods: Reference to the consensus recommendations by American Association of Physicist in Medicine, an incident learning system was specifically designed for reporting, investigating, and learning of individual radiotherapy incidents in a new established radiotherapy program, with 4D CBCT, Ultrasound guided radiotherapy, VMAT, gated treatment delivered on two new installed linacs. The incidents occurring in external beam radiotherapy from February, 2012 to January, 2014 were reported. Results: A total of 33 reports were analyzed, including 28 near misses and 5 incidents. Among them, 5 originated in imaging for planning, 25 in planning, 1 in plan transfer, 1 in commissioning and 1 in treatment delivery. Among them, three near misses originated in the safety barrier of the radiotherapy process. In terms of error type, 1 incident was classified as wrong patient, 7 near misses/incidents as wrong site, 6 as wrong laterality, 5 as wrong dose, 7 as wrong prescription, and 7 as suboptimal plan quality. 5 incidents were all classified as grade 1/2 of dosimetric severity, 1 as grade 0, and the other 4 as grade 1 of medical severity. For the causes/contributory factors, negligence, policy not followed, inadequate training, failure to develop an effective plan, and communication contributed to 19, 15, 12, 5 and 3 near misses/incidents, respectively. The average incident rate per 100 patients treated was 0.4; this rate fell to 0.28% in the second year from 0.56% in the first year. The rate of near miss fell to 1.24% from 2.22%. Conclusion: Effective incident learning can reduce the occurrence of near miss/incidents, enhance the culture of safety. Incident learning is an effective proactive method for improving the quality and safety of radiotherapy.

  19. METEOROLOGICAL INFLUENCES ON VAPOR INCIDENTS IN THE 200 EAST & 200 WEST TANK FARMS FROM CY2001 THRU CY2004

    SciTech Connect (OSTI)

    FAUROTE, J.M.

    2004-09-30

    Investigation into the meteorological influences on vapor incidents in the tank farms to determine what, if any, meteorological influences contribute to the reporting of odors, smells, vapors, and other gases. Weather phenomena, specifically barometric pressure, and wind velocity and direction can potentially cause or exacerbate a vapor release within the farm systems.

  20. Incident Management Preparedness and Coordination Toolkit

    SciTech Connect (OSTI)

    Koch, Daniel B.

    2013-04-01

    As with many professions, safety planners and first responders tend to be specialists in certain areas. To be truly useful, tools should be tailored to meet their specific needs. Thus, general software suites aimed at the professional geographic information system (GIS) community might not be the best solution for a first responder with little training in GIS terminology and techniques. On the other hand, commonly used web-based map viewers may not have the capability to be customized for the planning, response, and recovery (PR&R) mission. Data formats should be open and foster easy information flow among local, state, and federal partners. Tools should be free or low-cost to address real-world budget constraints at the local level. They also need to work both with and without a network connection to be robust. The Incident Management Preparedness and Coordination Toolkit (IMPACT) can satisfy many of these needs while working in harmony with established systems at the local, state, and federal levels. The IMPACT software framework, termed the Geospatial Integrated Problem Solving Environment (GIPSE), organizes tasks, tools, and resources for the end user. It uses the concept of software wizards to both customize and extend its functionality. On the Tasks panel are a number of buttons used to initiate various operations. Similar to macros, these task buttons launch scripts that utilize the full functionality of the underlying foundational components such as the SQL spatial database and ORNL-developed map editor. The user is presented with a series of instruction pages which are implemented with HTML for interactivity. On each page are links which initiate specific actions such as creating a map showing various features. Additional tasks may be quickly programmed and added to the panel. The end user can customize the graphical interface to faciltate its use during an emergency. One of the major components of IMPACT is the ORNL Geospatial Viewer (OGV). It is used to

  1. Incident Management Preparedness and Coordination Toolkit

    Energy Science and Technology Software Center (OSTI)

    2013-04-01

    As with many professions, safety planners and first responders tend to be specialists in certain areas. To be truly useful, tools should be tailored to meet their specific needs. Thus, general software suites aimed at the professional geographic information system (GIS) community might not be the best solution for a first responder with little training in GIS terminology and techniques. On the other hand, commonly used web-based map viewers may not have the capability tomore » be customized for the planning, response, and recovery (PR&R) mission. Data formats should be open and foster easy information flow among local, state, and federal partners. Tools should be free or low-cost to address real-world budget constraints at the local level. They also need to work both with and without a network connection to be robust. The Incident Management Preparedness and Coordination Toolkit (IMPACT) can satisfy many of these needs while working in harmony with established systems at the local, state, and federal levels. The IMPACT software framework, termed the Geospatial Integrated Problem Solving Environment (GIPSE), organizes tasks, tools, and resources for the end user. It uses the concept of software wizards to both customize and extend its functionality. On the Tasks panel are a number of buttons used to initiate various operations. Similar to macros, these task buttons launch scripts that utilize the full functionality of the underlying foundational components such as the SQL spatial database and ORNL-developed map editor. The user is presented with a series of instruction pages which are implemented with HTML for interactivity. On each page are links which initiate specific actions such as creating a map showing various features. Additional tasks may be quickly programmed and added to the panel. The end user can customize the graphical interface to faciltate its use during an emergency. One of the major components of IMPACT is the ORNL Geospatial Viewer (OGV). It is

  2. Discriminating electromagnetic radiation based on angle of incidence

    DOE Patents [OSTI]

    Hamam, Rafif E.; Bermel, Peter; Celanovic, Ivan; Soljacic, Marin; Yeng, Adrian Y. X.; Ghebrebrhan, Michael; Joannopoulos, John D.

    2015-06-16

    The present invention provides systems, articles, and methods for discriminating electromagnetic radiation based upon the angle of incidence of the electromagnetic radiation. In some cases, the materials and systems described herein can be capable of inhibiting reflection of electromagnetic radiation (e.g., the materials and systems can be capable of transmitting and/or absorbing electromagnetic radiation) within a given range of angles of incidence at a first incident surface, while substantially reflecting electromagnetic radiation outside the range of angles of incidence at a second incident surface (which can be the same as or different from the first incident surface). A photonic material comprising a plurality of periodically occurring separate domains can be used, in some cases, to selectively transmit and/or selectively absorb one portion of incoming electromagnetic radiation while reflecting another portion of incoming electromagnetic radiation, based upon the angle of incidence. In some embodiments, one domain of the photonic material can include an isotropic dielectric function, while another domain of the photonic material can include an anisotropic dielectric function. In some instances, one domain of the photonic material can include an isotropic magnetic permeability, while another domain of the photonic material can include an anisotropic magnetic permeability. In some embodiments, non-photonic materials (e.g., materials with relatively large scale features) can be used to selectively absorb incoming electromagnetic radiation based on angle of incidence.

  3. Microsoft Word - NNSS Incident Initial News Release.docx

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    January 29, 2013 Darwin.morgan@nnsa.doe.gov Incident at Nevada National Security Site LAS VEGAS, NV - Emergency responders are currently responding to an incident on the central portion of the Nevada National Security Site. More information will be released as it becomes available. -30- NSO-13-04

  4. System Safety Common Cause Analysis

    Energy Science and Technology Software Center (OSTI)

    1992-03-10

    The COMCAN fault tree analysis codes are designed to analyze complex systems such as nuclear plants for common causes of failure. A common cause event, or common mode failure, is a secondary cause that could contribute to the failure of more than one component and violates the assumption of independence. Analysis of such events is an integral part of system reliability and safety analysis. A significant common cause event is a secondary cause common tomore » all basic events in one or more minimal cut sets. Minimal cut sets containing events from components sharing a common location or a common link are called common cause candidates. Components share a common location if no barrier insulates any one of them from the secondary cause. A common link is a dependency among components which cannot be removed by a physical barrier (e.g.,a common energy source or common maintenance instructions).« less

  5. ORISE: REAC/TS Medical Management of Radiation Incidents

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Medical Management of Radiation Incidents As part of its primary mission for the U.S. Department of Energy (DOE), the Radiation Emergency Assistance CenterTraining Site (REACTS) ...

  6. NNSA Nuclear/Radiological Incident Response | National Nuclear Security

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Administration | (NNSA) December 01, 2008 The National Nuclear Security Administration (NNSA) has over 60 years of nuclear weapons experience in responding to nuclear and radiological accidents and incidents. NNSA provides technical support to the Departments of Homeland Security, Justice, State, and Defense for nuclear terrorism events and domestic nuclear weapon accidents and incidents. The NNSA emergency response assets also provide support to nuclear site and facility accidents and

  7. NNSA Nuclear/Radiological Incident Response | National Nuclear Security

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Administration | (NNSA) January 01, 2009 The National Nuclear Security Administration (NNSA) has more than 60 years of nuclear weapons experience in responding to nuclear and radiological accidents and incidents. NNSA provides technical support to the Departments of Homeland Security, Justice, State, and Defense for nuclear terrorism events and domestic nuclear weapon accidents and incidents. The NNSA emergency response assets also provide support to nuclear site and facility accidents and

  8. Radioactive Waste Issues in Major Nuclear Incidents | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Radioactive Waste Issues in Major Nuclear Incidents Radioactive Waste Issues in Major Nuclear Incidents S.Y. Chen*, Illinois Institute of Technology Abstract: Large amounts of radioactive waste had been generated in major nuclear accidents such as the Chernobyl nuclear accident in Ukraine of 1986 and the recent Fukushima nuclear accident in Japan of 2011. The wastes were generated due to the accidental releases of radioactive materials that resulted in widespread contamination throughout the

  9. The Department's Cyber Security Incident Management Program, IG-0787 |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Cyber Security Incident Management Program, IG-0787 The Department's Cyber Security Incident Management Program, IG-0787 The Department of Energy operates numerous interconnected computer networks and systems to help accon~plishit s strategic missions in the areas of energy, defense, science, and the environment. These systems are frequently subjected to sophisticated cyber attacks that could potentially affect the Department's ability to carry out its mission. During

  10. NUCLEAR INCIDENT CAPABILITIES, KNOWLEDGE & ENABLER LEVERAGING

    SciTech Connect (OSTI)

    Kinney, J.; Newman, J.; Goodwyn, A.; Dewes, J.

    2011-04-18

    The detonation of a 10 Kiloton Improvised Nuclear Device (IND) is a serious scenario that the United States must be prepared to address. The likelihood of a single nuclear bomb exploding in a single city is greater today than at the height of the Cold War. Layered defenses against domestic nuclear terrorism indicate that our government continues to view the threat as credible. The risk of such an event is further evidenced by terrorists desire to acquire nuclear weapons. The act of nuclear terrorism, particularly an act directed against a large population center in the United States, will overwhelm the capabilities of many local and state governments to respond, and will seriously challenge existing federal response capabilities. A 10 Kiloton IND detonation would cause total infrastructure damage in a 3-mile radius and levels of radiation spanning out 3,000 square miles. In a densely populated urban area, the anticipated casualties would be in excess of several hundred thousand. Although there would be enormous loss of life, housing and infrastructure, an IND detonation is a recoverable event. We can reduce the risk of these high-consequence, nontraditional threats by enhancing our nuclear detection architecture and establishing well planned and rehearsed plans for coordinated response. It is also important for us to identify new and improved ways to foster collaboration regarding the response to the IND threat to ensure the demand and density of expertise required for such an event is postured and prepared to mobilize, integrate, and support a myriad of anticipated challenges. We must be prepared to manage the consequences of such an event in a deliberate manner and get beyond notions of total devastation by adopting planning assumptions around survivability and resiliency. Planning for such a scenario needs to be decisive in determining a response based on competencies and desired outcomes. It is time to synthesize known threats and plausible consequences into

  11. Material development in the SI{sub 3}N{sub 4} system using glass encapsulated Hip`ing. Final report, Phase 2: DOE/ORNL Ceramic Technology Project

    SciTech Connect (OSTI)

    Corbin, N.D.; Sundberg, G.J.; Siebein, K.N.; Willkens, C.A.; Pujari, V.K.; Rossi, G.A.; Hansen, J.S.; Chang, C.L.; Hammarstrom, J.L.

    1992-04-01

    This report covers a two-year program to develop fully dense Si{sub 3}N{sub 4} matrix SiC whisker composites with enhanced properties over monolithic Si{sub 3}N{sub 4} materials. The primary goal was to develop a composite with a fracture toughness > 10 MPa{radical}m, capable of using high pressure glass encapsulated HIP`ing. Coating methods were developed to apply thin (<150nm) stoichiometric BN layers to SiC whiskers and also to apply a dual coating of SiC over carbon to the whiskers. Fracture toughness of the composites was determined to increase as the quantity of whiskers (or elongated grains) with their axis perpendicular to the crack plane increased. Of the interface compositions evaluated in this effort, carbon was determined to be the most effective for increasing toughness. The highest toughnesses (6.8--7.0 MPa{radical}m) were obtained with uniaxially aligned carbon coated whiskers. There was no evidence of the carbon coating compromising the oxidation resistance of the composites at 1370{degree}C.

  12. Analysis of incident-energy dependence of delayed neutron yields in actinides

    SciTech Connect (OSTI)

    Nasir, Mohamad Nasrun bin Mohd Metorima, Kouhei Ohsawa, Takaaki Hashimoto, Kengo

    2015-04-29

    The changes of delayed neutron yields (?{sub d}) of Actinides have been analyzed for incident energy up to 20MeV using realized data of precursor after prompt neutron emission, from semi-empirical model, and delayed neutron emission probability data (P{sub n}) to carry out a summation method. The evaluated nuclear data of the delayed neutron yields of actinide nuclides are still uncertain at the present and the cause of the energy dependence has not been fully understood. In this study, the fission yields of precursor were calculated considering the change of the fission fragment mass yield based on the superposition of fives Gaussian distribution; and the change of the prompt neutrons number associated with the incident energy dependence. Thus, the incident energy dependent behavior of delayed neutron was analyzed.The total number of delayed neutron is expressed as ?{sub d}=?Y{sub i} P{sub ni} in the summation method, where Y{sub i} is the mass yields of precursor i and P{sub ni} is the delayed neutron emission probability of precursor i. The value of Y{sub i} is derived from calculation of post neutron emission mass distribution using 5 Gaussian equations with the consideration of large distribution of the fission fragments. The prompt neutron emission ?{sub p} increases at higher incident-energy but there are two different models; one model says that the fission fragment mass dependence that prompt neutron emission increases uniformly regardless of the fission fragments mass; and the other says that the major increases occur at heavy fission fragments area. In this study, the changes of delayed neutron yields by the two models have been investigated.

  13. ARM - What Causes Global Warming?

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Teachers' Toolbox Lesson Plans What Causes Global Warming? On earth we get energy from the sun's light. As you know, it gets hot outside if the sun is shining brightly on a summer ...

  14. ARM - What Causes Global Warming?

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ThinkersWhat Causes Global Warming? Outreach Home Room News Publications Traditional Knowledge Kiosks Barrow, Alaska Tropical Western Pacific Site Tours Contacts Students Study Hall About ARM Global Warming FAQ Just for Fun Meet our Friends Cool Sites Teachers Teachers' Toolbox Lesson Plans What Causes Global Warming? What is the basis for the predictions concerning global warming? There are several gases in the air, collectively called greenhouse gases, that trap the infrared radiation emitted

  15. Headquarters Facilities Master Security Plan- Chapter 11, Incidents of Security Concern

    Office of Energy Efficiency and Renewable Energy (EERE)

    2016 Headquarters Facilities Master Security Plan - Chapter 11, Incidents of Security Concern Describes DOE Headquarters procedures for reporting, investigating, and correcting Incidents of Security Concern.

  16. Follow-up Audit of the Department's Cyber Security Incident Management...

    Energy Savers [EERE]

    information security incident center, law enforcement agencies and Inspectors General. ... program and adversely impacted the ability of law enforcement to investigate incidents. ...

  17. Violation of Laws, Losses, and Incidents of Security Concerns

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1992-09-15

    To set forth Department of Energy (DOE) procedures to assure timely and effective action relating to violations of criminal, laws, loses, and incidents of security concern to DOE. Cancels DOE O 5631.5. Canceled by DOE O 470.1 of 9-28-1995.

  18. PSM case history: Regulatory compliance can prevent catastrophic incidents

    SciTech Connect (OSTI)

    Kiihne, E.J.; Mannan, M. [RMT/Jones and Neuse, Inc., Austin, TX (United States)

    1995-12-31

    As mandated by the Clean Air Act Amendments of 1990, the Occupational Safety and Health Administration promulgated on February 24, 1992 the Process Safety Management (PSM) rule: 29 CFR 1910.119. The PSM rule represents a holistic program which requires facilities to develop, implement and practice 14 different elements. Each of the 14 elements are significant in the protection of health and safety of all employees and personnel working in and around the plant site. PSM programs developed in compliance with the PSM rule are expected to reduce the probability and consequence of occurrence of hazardous incidents. This paper presents a real life incident that occurred in a plant before a PSM program was put in place. A detailed description of the incident is provided with appropriate discussions of non compliance with the PSM rule. Finally, the paper provides a theoretical scenario where a fully operational PSM program would have prevented the incident. The case history and discussion provided in this paper also reinforces the concept of maintaining process and equipment integrity through multiple barriers of safety. A fully operational PSM program represents such a multiple barrier safety system.

  19. ROOT CAUSE ANALYSIS PROGRAM MANUAL

    SciTech Connect (OSTI)

    Gravois, Melanie C.

    2007-05-02

    Root Cause Analysis (RCA) identifies the cause of an adverse condition that, if corrected, will preclude recurrence or greatly reduce the probability of recurrence of the same or similar adverse conditions and thereby protect the health and safety of the public, the workers, and the environment. This procedure sets forth the requirements for management determination and the selection of RCA methods and implementation of RCAs that are a result of significant findings from Price-Anderson Amendments Act (PAAA) violations, occurrences/events, Significant Adverse Conditions, and external oversight Corrective Action Requests (CARs) generated by the Office of Enforcement (PAAA headquarters), the U.S. Environmental Protection Agency, and other oversight entities against Lawrence Berkeley National Laboratory (LBNL). Performance of an RCA may result in the identification of issues that should be reported in accordance with the Issues Management Program Manual.

  20. Researchers correlate incidences of rheumatoid arthritis and giant cell

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    arteritis with solar cycles | Princeton Plasma Physics Lab Researchers correlate incidences of rheumatoid arthritis and giant cell arteritis with solar cycles By John Greenwald June 15, 2015 Tweet Widget Google Plus One Share on Facebook A coronal mass ejection hurling plasma from the sun (Photo by NASA) A coronal mass ejection hurling plasma from the sun What began as a chat between husband and wife has evolved into an intriguing scientific discovery. The results, published in May in BMJ

  1. Researchers correlate incidences of rheumatoid arthritis and giant cell

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    arteritis with solar cycles | Princeton Plasma Physics Lab Researchers correlate incidences of rheumatoid arthritis and giant cell arteritis with solar cycles By John Greenwald June 15, 2015 Tweet Widget Google Plus One Share on Facebook A coronal mass ejection hurling plasma from the sun (Photo by NASA) A coronal mass ejection hurling plasma from the sun What began as a chat between husband and wife has evolved into an intriguing scientific discovery. The results, published in May in BMJ

  2. ORISE: REAC/TS Medical Management of Radiation Incidents

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Medical Management of Radiation Incidents As part of its primary mission for the U.S. Department of Energy (DOE), the Radiation Emergency Assistance Center/Training Site (REAC/TS) at the Oak Ridge Institute for Science and Education (ORISE) is available 24 hours a day, seven days a week to consult with officials from any federal, state or local government agency; industries; international governments or organizations; or individuals needing assistance with the medical management of a radiation

  3. INSPECTION REPORT Technetium-99 Incident at Los Alamos National Laboratory

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Technetium-99 Incident at Los Alamos National Laboratory OAI-L-16-13 August 2016 U.S. Department of Energy Office of Inspector General Office of Audits and Inspections Department of Energy Washington, DC 20585 August 2, 2016 MEMORANDUM FOR THE ASSOCIATE ADMINISTRATOR FOR EMERGENCY OPERATIONS, NATIONAL NUCLEAR SECURITY ADMINISTRATION FROM: David Sedillo Deputy Assistant Inspector General for Audits and Inspections Office of Inspector General SUBJECT: INFORMATION: Inspection Report on the

  4. The effect of diet and exercise on incidence of 7,12dimethylbenz...

    Office of Scientific and Technical Information (OSTI)

    The effect of diet and exercise on incidence of 7,12 dimethylbenz(a)anthracene-induced ... appeared to be related to mammary tumor incidence rather than body wt. or dietary fat. ...

  5. Over-Pressurized Drums: Their Causes and Mitigation

    SciTech Connect (OSTI)

    Simmons, Fred; Kuntamukkula, Murty; Quigley, David; Robertson, Janeen; Freshwater, David

    2009-07-10

    Having to contend with bulging or over-pressurized drums is, unfortunately, a common event for people storing chemicals and chemical wastes. (Figure 1) The Department of Energy alone reported over 120 incidents of bulging drums between 1992 and 1999 (1). Bulging drums can be caused by many different mechanisms, represent a number of significant hazards and can be tricky to mitigate. In this article, we will discuss reasons or mechanisms by which drums can become over-pressurized, recognition of the hazards associated with and mitigation of over-pressurized drums, and methods that can be used to prevent drum over-pressurization from ever occurring. Drum pressurization can represent a significant safety hazard. Unless recognized and properly mitigated, improperly manipulated pressurized drums can result in employee exposure, employee injury, and environmental contamination. Therefore, recognition of when a drum is pressurized and knowledge of pressurized drum mitigation techniques is essential.

  6. Federal Response Assets for a Radioactive Dispersal Device Incident

    SciTech Connect (OSTI)

    Sullivan,T.

    2009-06-30

    If a large scale RDD event where to occur in New York City, the magnitude of the problem would likely exceed the capabilities of City and State to effectively respond to the event. New York State could request Federal Assistance if the United States President has not already made the decision to provide it. The United States Federal Government has a well developed protocol to respond to emergencies. The National Response Framework (NRF) describes the process for responding to all types of emergencies including RDD incidents. Depending on the location and type of event, the NRF involves appropriate Federal Agencies, e.g., Department of Homeland Security (DHS), the Department of Energy (DOE), Environmental Protection Agency (EPA), United States Coast Guard (USCG), Department of Defense (DOD), Department of Justice (DOJ), Department of Agriculture (USDA), and Nuclear Regulatory Commission (NRC). The Federal response to emergencies has been refined and improved over the last thirty years and has been tested on natural disasters (e.g. hurricanes and floods), man-made disasters (oil spills), and terrorist events (9/11). However, the system has never been tested under an actual RDD event. Drills have been conducted with Federal, State, and local agencies to examine the initial (early) phases of such an event (TopOff 2 and TopOff 4). The Planning Guidance for Protection and Recovery Following Radiological Dispersal Device (RDD) and Improvised Nuclear Device (IND) incidents issued by the Department of Homeland Security (DHS) in August 2008 has never been fully tested in an interagency exercise. Recently, another exercise called Empire 09 that was situated in Albany, New York was conducted. Empire 09 consists of 3 different exercises be held in May and June, 2009. The first exercise, May 2009, involved a table top exercise for phase 1 (0-48 hours) of the response to an RDD incident. In early June, a full-scale 3- day exercise was conducted for the mid-phase response (48

  7. Oblique incidence effects in direct x-ray detectors: A first-order approximation using a physics-based analytical model

    SciTech Connect (OSTI)

    Badano, Aldo; Freed, Melanie; Fang Yuan

    2011-04-15

    orthogonal direction. The results suggest that the oblique incidence effect in direct detectors can be considered to be caused mostly by the geometry of the path where the x-ray beam and its secondary particles deposit energy in the semiconductor layer.

  8. Reaction cross sections of carbon isotopes incident on a proton

    SciTech Connect (OSTI)

    Abu-Ibrahim, B.; Horiuchi, W.; Kohama, A.; Suzuki, Y.

    2008-03-15

    We systematically study total reaction cross sections of carbon isotopes with N=6-16 on a proton target for wide range of incident energies. An emphasis is put on the difference from the case of a carbon target. The calculations include the reaction cross sections of {sup 19,20,22}C at 40A MeV, the data of which have recently been measured at RIKEN. The Glauber theory is used to calculate the reaction cross sections. To describe the intrinsic structure of the carbon isotopes, we use a Slater determinant generated from a phenomenological mean-field potential, and construct the density distributions. To go beyond the simple mean-field model, we adopt two types of dynamical models: One is a core+n model for odd-neutron nuclei, and the other is a core+n+n model for {sup 16}C and {sup 22}C. We propose empirical formulas which are useful in predicting unknown cross sections.

  9. Residential radon and lung cancer incidence in a Danish cohort

    SciTech Connect (OSTI)

    Braeuner, Elvira V.; Andersen, Claus E.; Sorensen, Mette; Jovanovic Andersen, Zorana; Center for Epidemiology Screening, Department of Public Health, University of Copenhagen ; Gravesen, Peter; Ulbak, Kaare; Hertel, Ole; Pedersen, Camilla; Overvad, Kim; Tjonneland, Anne; Raaschou-Nielsen, Ole

    2012-10-15

    High-level occupational radon exposure is an established risk factor for lung cancer. We assessed the long-term association between residential radon and lung cancer risk using a prospective Danish cohort using 57,053 persons recruited during 1993-1997. We followed each cohort member for cancer occurrence until 27 June 2006, identifying 589 lung cancer cases. We traced residential addresses from 1 January 1971 until 27 June 2006 and calculated radon at each of these addresses using information from central databases regarding geology and house construction. Cox proportional hazards models were used to estimate incidence rate ratios (IRR) and 95% confidence intervals (CI) for lung cancer risk associated with residential radon exposure with and without adjustment for sex, smoking variables, education, socio-economic status, occupation, body mass index, air pollution and consumption of fruit and alcohol. Potential effect modification by sex, traffic-related air pollution and environmental tobacco smoke was assessed. Median estimated radon was 35.8 Bq/m{sup 3}. The adjusted IRR for lung cancer was 1.04 (95% CI: 0.69-1.56) in association with a 100 Bq/m{sup 3} higher radon concentration and 1.67 (95% CI: 0.69-4.04) among non-smokers. We found no evidence of effect modification. We find a positive association between radon and lung cancer risk consistent with previous studies but the role of chance cannot be excluded as these associations were not statistically significant. Our results provide valuable information at the low-level radon dose range.

  10. Sputter deposition of Al-doped ZnO films with various incident angles

    SciTech Connect (OSTI)

    Sato, Yasushi; Yanagisawa, Kei; Oka, Nobuto; Nakamura, Shin-ichi; Shigesato, Yuzo

    2009-09-15

    Al-doped ZnO (AZO) films were sputter deposited on glass substrates heated at 200 degree sign C under incident angles of sputtered particles at 0 degree sign (incidence normal to substrate), 20 deg., 40 deg., 60 deg., and 80 deg. In the case of normal incidence, x-ray diffraction pole figures show a strong [001] preferred orientation normal to the film surface. In contrast, in the case wherein the incident angles were higher than 60 degree sign , the [001] orientation inclined by 25 deg. - 35 deg. toward the direction of sputtered particles. Transmission electron microscopy revealed that the tilt angle of the [001] orientation increased with increasing angle of the incident sputtered particles, whereas the columnar structure did not show any sign of inclination with respect to the substrate plane.

  11. An expert system for automating security incident assessment using OPS5 in an Ada environment

    SciTech Connect (OSTI)

    Canales, T.W.; Smart, J.C.

    1988-01-29

    An expert system that automatically assesses security incidents is being developed at Lawrence Livermore National Laboratory. The expert system associates, classifies, and prioritizes monitored sensor events. The outcome of these processes is a dynamic representation of the state of Laboratory security in the form of security ''incidents''. A graphical representation of the incidents is integrated into a map-oriented console monitor that provides the operator with a comprehensive view of incidents and their locations. A prototype expert system has been developed using the OPS5 rule-based language. A large Ada-based program provides control of the map display system and interfaces to the various monitoring and access-control devices. In addition to the expert system operation, the issues and methods involved in integrating the OPS5-based incident-assessment system to the large Ada-based control program are discussed. 7 refs., 7 figs.

  12. Do solar cycles influence giant cell arteritis and rheumatoid arthritis incidence?

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Wing, Simon; Rider, Lisa G.; Johnson, Jay R.; Miller, Federick W.; Matteson, Eric L.; Crowson, C. S.; Gabriel, S. E.

    2015-05-15

    Our objective was to examine the influence of solar cycle and geomagnetic effects on the incidence of giant cell arteritis (GCA) and rheumatoid arthritis (RA). Methods: We used data from patients with GCA (1950-2004) and RA (1955-2007) obtained from population-based cohorts. Yearly trends in age-adjusted and sex-adjusted incidence were correlated with the F10.7 index (solar radiation at 10.7 cm wavelength, a proxy for the solar extreme ultraviolet radiation) and AL index (a proxy for the westward auroral electrojet and a measure of geomagnetic activity). Fourier analysis was performed on AL, F10.7, and GCA and RA incidence rates. Results: The correlationmore » of GCA incidence with AL is highly significant: GCA incidence peaks 0-1 year after the AL reaches its minimum (ie, auroral electrojet reaches a maximum). The correlation of RA incidence with AL is also highly significant. RA incidence rates are lowest 5-7 years after AL reaches maximum. AL, GCA and RA incidence power spectra are similar: they have a main peak (periodicity) at about 10 years and a minor peak at 4-5 years. However, the RA incidence power spectrum main peak is broader (8-11 years), which partly explains the lower correlation between RA onset and AL. The auroral electrojets may be linked to the decline of RA incidence more strongly than the onset of RA. The incidences of RA and GCA are aligned in geomagnetic latitude. Conclusions: AL and the incidences of GCA and RA all have a major periodicity of about 10 years and a secondary periodicity at 4-5 years. Geomagnetic activity may explain the temporal and spatial variations, including east-west skewness in geographic coordinates, in GCA and RA incidence, although the mechanism is unknown. Lastly, the link with solar, geospace and atmospheric parameters need to be investigated. These novel findings warrant examination in other populations and with other autoimmune diseases.« less

  13. Status Update on the NCRP Scientific Committee SC 5-1 Report: Decision Making for Late-Phase Recovery from Nuclear or Radiological Incidents - 13450

    SciTech Connect (OSTI)

    Chen, S.Y.

    2013-07-01

    been expanded to include off-site contamination from major nuclear power plant accidents as well as other nuclear or radiological incidents. The expanded application under the current guidance has thus led to a broadened scope of the report, which is reflected in its new title, Decision Making for Late-Phase Recovery from Nuclear or Radiological Incidents. The NCRP report, which is due for publication in 2013, will substantiate the current DHS guidance by clarifying and elaborating on the processes required for the development and implementation of procedures for optimizing decision making for late-phase recovery, enabling the establishment of cleanup goals on a site-specific basis. The report will contain a series of topics addressing important issues related to the long-term recovery from nuclear or radiological incidents. Special topics relevant to supporting the optimization of the decision-making process will include cost-benefit analysis, radioactive waste management, risk communication, stakeholder interaction, risk assessment, and decontamination approaches and techniques. The committee also evaluated past nuclear and radiological incidents for their relevance to the report, including the emerging issues associated with the Fukushima nuclear accident. Thus, due to the commonality of the late-phase issues (such as the potential widespread contamination following an event), the majority of the information pertaining to the response in the late-phase decision-making period, including site-specific optimization framework and approach, could be used or adapted for use in case of similar situations that are not due to terrorism, such as those that would be caused by major nuclear facility accidents or radiological incidents. To ensure that the report and the NCRP recommendations are current and relevant to the effective implementation of federal guidance, SC 5-1 has actively coordinated with the agencies of interest and other relevant stakeholders throughout the

  14. Structure and Dynamics of Polymer Nanocomposites by Grazing-Incidence X-Ray

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Techniques (Presentation) | Department of Energy Structure and Dynamics of Polymer Nanocomposites by Grazing-Incidence X-Ray Techniques (Presentation) Structure and Dynamics of Polymer Nanocomposites by Grazing-Incidence X-Ray Techniques (Presentation) Presented at the High Temperature Membrane Working Group (HTMWG) Meeting held on October 10, 2007 in Washington, D.C. htwmg_oct07_wang.pdf (1.78 MB) More Documents & Publications Block Copolymer Separators for Lithium Batteries FY 2004

  15. Investigation of Incident at Waste Isolation Pilot Plant by Technical Assessment Team

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Investigation of Incident at Waste Isolation Pilot Plant by Technical Assessment Team March 2015 Overall Findings On February 14, 2014, an incident in Panel 7 Room 7 (P7R7) of the Waste Isolation Pilot Plant (WIPP) underground repository resulted in the release of radioactive material into the environment and contaminated 21 people with low-level radioactivity. The Technical Assessment Team (TAT) concluded that one drum, Drum 68660, was the source of radioactive contamination released during the

  16. Sensitivity of fenestration solar gain to source spectrum and angle of incidence

    SciTech Connect (OSTI)

    McCluney, W.R.

    1996-12-31

    The solar heat gain coefficient (SHGC) is the fraction of solar radiant flux incident on a fenestration system entering a building as heat gain. In general it depends on both the angle of incidence and the spectral distribution of the incident solar radiation. In attempts to improve energy performance and user acceptance of high-performance glazing systems, manufacturers are producing glazing systems with increasing spectral selectivity. This poses potential difficulties for calculations of solar heat gain through windows based upon the use of a single solar spectral weighting function. The sensitivity of modern high-performance glazing systems to both the angle of incidence and the shape of the incident solar spectrum is examined using a glazing performance simulation program. It is found that as the spectral selectivity of the glazing system increases, the SHGC can vary as the incident spectral distribution varies. The variations can be as great as 50% when using several different representative direct-beam spectra. These include spectra having low and high air masses and a standard spectrum having an air mass of 1.5. The variations can be even greater if clear blue diffuse skylight is considered. It is recommended that the current broad-band shading coefficient method of calculating solar gain be replaced by one that is spectral based.

  17. ROOT CAUSE ANALYSIS AND CORRECTIVE ACTION PLAN CLOSURE REPORT...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ROOT CAUSE ANALYSIS AND CORRECTIVE ACTION PLAN CLOSURE REPORT ROOT CAUSE ANALYSIS AND CORRECTIVE ACTION PLAN CLOSURE REPORT The Department conducted a root cause analysis (RCA) ...

  18. Occupational obstructive airway diseases in Germany: Frequency and causes in an international comparison

    SciTech Connect (OSTI)

    Latza, U.; Baur, X.

    2005-08-01

    Occupational inhalative exposures contribute to a significant proportion of obstructive airway diseases (OAD), namely chronic obstructive pulmonary disease (COPD) and asthma. The number of occupational OAD in the German industrial sector for the year 2003 are presented. Other analyses of surveillance data were retrieved from Medline. Most confirmed reports of OAD are cases of sensitizer induced occupational asthma (625 confirmed cases) followed by COPD in coal miners (414 cases), irritant induced occupational asthma (156 cases), and isocyanate asthma (54 cases). Main causes of occupational asthma in Germany comprise flour/flour constituents (35.9%), food/feed dust (9.0%), and isocyanates (6.5%). Flour and grain dust is a frequent cause of occupational asthma in most European countries and South Africa. Isocyanates are still a problem worldwide. Although wide differences in the estimated incidences between countries exist due to deficits in the coverage of occupational OAD, the high numbers necessitate improvement of preventive measures.

  19. Land subsidence caused by fluid removal

    SciTech Connect (OSTI)

    Allen, D.R.

    1988-01-01

    Subsidence caused by the removal of both fluids and solids is a world-wide environmental problem. The extraction of coal, natural gas, oil, fresh water, brine, etc, have all caused subsidence at various times and locations. Although subsidence related to oil and geothermal field operations is relatively rare, it has caused severe problems in the past and currently. In porous media, the surface is held stable by underground support from the matrix rocks and the pore fluids. Upon the production of reservoir fluids, pore fluid pressure drops and the portion of geostatic loading borne by the pore fluids is transferred to rock matrix. This increase in load causes both elastic and inelastic deformation of the skeletal structure of the reservoir being produced. Pore volume is lost, the reservoir decreases in the vertical dimension, and subsidence might occur at the surface. As soon as subsidence is detected, most observers try to estimate the maximum that might occur. This prediction has proved to be a very difficult proposition owing to geologic complexities and unknown petrophysical data. Seven examples of subsidence in oil and geothermal operations show many similarities, such as high porosity, large fluid removal, limited arching in the structure, large width to depth ratios, usually poor cementation, grabens and normal faulting, and coincidence of time and place of fluid removal and subsidence. None of these are critical, but the result in a field that has most of these properties often is surface subsidence. Reservoir compaction in situ has been measured by two methods: (1) casing joint length changes and (2) the location of radioactive bullets shot into the formation. Casing joint measurements, although having accuracy limitations, usually furnish data as to the degree of compaction without previous planning.

  20. EP&R Standards Project Report: Technical Review of National Incident Management Standards

    SciTech Connect (OSTI)

    Stenner, Robert D.

    2007-04-24

    The importance and necessity for a fully developed and implemented National Incident Management System (NIMS) has been demonstrated in recent years by the impact of national events such as Hurricane Katrina in 2005. Throughout the history of emergency response to major disasters, especially when multiple response organizations are involved, there have been systemic problems in the consistency and uniformity of response operations. Identifying national standards that support the development and implementation of NIMS is key to helping solve these systemic problems. The NIMS seeks to provide uniformity and consistency for incident management by using common terminology and protocols that will enable responders to coordinate their efforts to ensure an efficient response.

  1. Mass Estinctions Caused by Large Bolide Impacts

    SciTech Connect (OSTI)

    Lavarez, Luis W.

    1987-01-01

    In this talk, I will describe the wealth of evidence that has forced my colleagues and me to conclude that the great mass extinctions, 65 million years ago, were caused by a large bolide impact on the earth. Bolide is a new word to most people, and it means any piece of solar system debris, such as a meteorite, asteroid, or comet nucleus. As I will show, the bolide responsible for the extinction of most of the then existing species, including the dinosaurs, was about 10 kilometers in diameter.

  2. Solid state laser disk amplifer architecture: the normal-incidence stack

    DOE Patents [OSTI]

    Dane, C. Brent; Albrecht, Georg F.; Rotter, Mark D.

    2005-01-25

    Normal incidence stack architecture coupled with the development of diode array pumping enables the power/energy per disk to be increased, a reduction in beam distortions by orders of magnitude, a beam propagation no longer restricted to only one direction of polarization, and the laser becomes so much more amendable to robust packaging.

  3. Biomedical nuclear and X-ray imager using high-energy grazing incidence mirrors

    DOE Patents [OSTI]

    Ziock, Klaus-Peter; Craig, William W.; Hasegawa, Bruce; Pivovaroff, Michael J.

    2005-09-27

    Imaging of radiation sources located in a subject is explored for medical applications. The approach involves using grazing-incidence optics to form images of the location of radiopharmaceuticals administered to a subject. The optics are "true focusing" optics, meaning that they project a real and inverted image of the radiation source onto a detector possessing spatial and energy resolution.

  4. Nuclear plant cancellations: causes, costs, and consequences

    SciTech Connect (OSTI)

    Not Available

    1983-04-01

    This study was commissioned in order to help quantify the effects of nuclear plant cancellations on the Nation's electricity prices. This report presents a historical overview of nuclear plant cancellations through 1982, the costs associated with those cancellations, and the reasons that the projects were terminated. A survey is presented of the precedents for regulatory treatment of the costs, the specific methods of cost recovery that were adopted, and the impacts of these decisions upon ratepayers, utility stockholders, and taxpayers. Finally, the report identifies a series of other nuclear plants that remain at risk of canellation in the future, principally as a result of similar demand, finance, or regulatory problems cited as causes of cancellation in the past. The costs associated with these potential cancellations are estimated, along with their regional distributions, and likely methods of cost recovery are suggested.

  5. Statistics Show Bearing Problems Cause the Majority of Wind Turbine...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Statistics Show Bearing Problems Cause the Majority of Wind Turbine Gearbox Failures Statistics Show Bearing Problems Cause the Majority of Wind Turbine Gearbox Failures September ...

  6. Counting small RNA in disease-causing organisms

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    in disease-causing organisms Los Alamos researchers demonstrated improved technical methods capable of directly counting small RNA molecules in pathogenic (disease-causing)...

  7. SU-E-T-524: Web-Based Radiation Oncology Incident Reporting and Learning System (ROIRLS)

    SciTech Connect (OSTI)

    Kapoor, R; Palta, J; Hagan, M; Grover, S; Malik, G

    2014-06-01

    Purpose: Describe a Web-based Radiation Oncology Incident Reporting and Learning system that has the potential to improve quality of care for radiation therapy patients. This system is an important facet of continuing effort by our community to maintain and improve safety of radiotherapy.Material and Methods: The VA National Radiation Oncology Program office has embarked on a program to electronically collect adverse events and near miss data of radiation treatment of over 25,000 veterans treated with radiotherapy annually. Software used for this program is deployed on the VAs intranet as a Website. All data entry forms (adverse event or near miss reports, work product reports) utilize standard causal, RT process step taxonomies and data dictionaries defined in AAPM and ASTRO reports on error reporting (AAPM Work Group Report on Prevention of Errors and ASTROs safety is no accident report). All reported incidents are investigated by the radiation oncology domain experts. This system encompasses the entire feedback loop of reporting an incident, analyzing it for salient details, and developing interventions to prevent it from happening again. The operational workflow is similar to that of the Aviation Safety Reporting System. This system is also synergistic with ROSIS and SAFRON. Results: The ROIRLS facilitates the collection of data that help in tracking adverse events and near misses and develop new interventions to prevent such incidents. The ROIRLS electronic infrastructure is fully integrated with each registered facility profile data thus minimizing key strokes and multiple entries by the event reporters. Conclusions: OIRLS is expected to improve the quality and safety of a broad spectrum of radiation therapy patients treated in the VA and fulfills our goal of Effecting Quality While Treating Safely The Radiation Oncology Incident Reporting and Learning System software used for this program has been developed, conceptualized and maintained by TSG Innovations

  8. Incident Energy Dependence of pt Correlations at RHIC

    SciTech Connect (OSTI)

    Adams, J.; Aggarwal, M. M.; Ahammed, Z.; Amonett, J.; Anderson, B. D.; Arkhipkin, D.; Averichev, G. S.; Badyal, S. K.; Bai, Y.; Balewski, J.; Barannikova, O.; Barnby, L. S.; Baudot, J.; Bekele, S.; Belaga, V. V.; Bellwied, R.; Berger, J.; Bezverkhny, B. I; Bharadwaj, S.; Bhasin, A.; Bhati, A. K.; Bhatia, V. S.; Bichsel, H.; Billmeier, A.; Bland, L. C.; Blyth, C. O.; Bonner, B. E.; Botje, M.; Boucham, A.; Brandin, A. V.; Bravar, A.; Bystersky, M.; Cadman, R. V.; Cai, X. Z.; Caines, H.; Castillo, J.; Cebra, D.; Chajecki, Z.; Chaloupka, P.; Chattopadhyay, S.; Chen, H. F.; Chen, Y.; Cheng, J.; Cherney, M.; Chikanian, A.; Christie, W.; Coffin, J. P.; Cormier, T. M.; Cramer, J. G.; Crawford, H. J.; Das, D.; Das, S.; de Moura, M. M.; Derevschikov, A. A.; Didenko, L.; Dietel, T.; Dogra, S. M.; Dong, W. J.; Dong, X.; Draper, J. E.; Du, F.; Dubey, A. K.; Dunin, V. B.; Dunlop, J. C.; Dutta Mazumdar, M. R.; Eckardt, V.; Edwards, W. R.; Efimov, L. G.; Emelianov, V.; Engelage, J.; Eppley, G.; Erazmus, B.; Estienne, M.; Fachini, P.; Faivre, J.; Fatemi, R.; Fedorisin, J.; Filimonov, K.; Filip, P.; Finch, E.; Fine, V.; Fisyak, Y.; Fomenko, K.; Fu, J.; Gagliardi, C. A.; Gaillard, L.; Gans, J.; Ganti, M. S.; Gaudichet, L.; Geurts, F.; Ghazikhanian, V.; Ghosh, P.; Gonzalez, J. E.; Grachov, O.; Grebenyuk, O.; Grosnick, D.; Guertin, S. M.; Guo, Y.; Gupta, A.; Gutierrez, T. D.; Hallman, T. J.; Hamed, A.; Hardtke, D.; Harris, J. W.; Heinz, M.; Henry, T. W.; Hepplemann, S.; Hippolyte, B.; Hirsch, A.; Hjort, E.; Hoffmann, G. W.; Huang, H. Z.; Huang, S. L.; Hughes, E. W.; Humanic, T. J.; Igo, G.; Ishihara, A.; Jacobs, P.; Jacobs, W. W.; Janik, M.; Jiang, H.; Jones, P. G.; Judd, E. G.; Kabana, S.; Kang, K.; Kaplan, M.; Keane, D.; Khodyrev, V. Yu; Kiryluk, J.; Kisiel, A.; Kislov, E. M.; Klay, J.; Klein, S. R.; Koetke, D. D.; Kollegger, T.; Kopytine, M.; Kotchenda, L.; Kramer, M.; Kravtsov, P.; Kravtsov, V. I.; Krueger, K.; Kuhn, C.; Kulikov, A. I.; Kumar, A.; Kutuev, R. Kh

    2005-10-01

    We present results for two-particle transverse momentum correlations, Δpt,iΔt,j, as a function of event centrality for Au+Au collisions at √(sNN) = 20, 62, 130, and 200 GeV at the Relativistic Heavy Ion Collider. We observe correlations decreasing with centrality that are similar at all four incident energies. The correlations multiplied by the multiplicity density increase with incident energy and the centrality dependence may show evidence of processes such as thermalization, jet production, or the saturation of transverse flow. The square root of the correlations divided by the event-wise average transverse momentum per event shows little or no beam energy dependence and generally agrees with previous measurements at the Super Proton Synchrotron.

  9. A Planning Tool for Estimating Waste Generated by a Radiological Incident and Subsequent Decontamination Efforts - 13569

    SciTech Connect (OSTI)

    Boe, Timothy; Lemieux, Paul; Schultheisz, Daniel; Peake, Tom; Hayes, Colin

    2013-07-01

    Management of debris and waste from a wide-area radiological incident would probably constitute a significant percentage of the total remediation cost and effort. The U.S. Environmental Protection Agency's (EPA's) Waste Estimation Support Tool (WEST) is a unique planning tool for estimating the potential volume and radioactivity levels of waste generated by a radiological incident and subsequent decontamination efforts. The WEST was developed to support planners and decision makers by generating a first-order estimate of the quantity and characteristics of waste resulting from a radiological incident. The tool then allows the user to evaluate the impact of various decontamination/demolition strategies on the waste types and volumes generated. WEST consists of a suite of standalone applications and Esri{sup R} ArcGIS{sup R} scripts for rapidly estimating waste inventories and levels of radioactivity generated from a radiological contamination incident as a function of user-defined decontamination and demolition approaches. WEST accepts Geographic Information System (GIS) shape-files defining contaminated areas and extent of contamination. Building stock information, including square footage, building counts, and building composition estimates are then generated using the Federal Emergency Management Agency's (FEMA's) Hazus{sup R}-MH software. WEST then identifies outdoor surfaces based on the application of pattern recognition to overhead aerial imagery. The results from the GIS calculations are then fed into a Microsoft Excel{sup R} 2007 spreadsheet with a custom graphical user interface where the user can examine the impact of various decontamination/demolition scenarios on the quantity, characteristics, and residual radioactivity of the resulting waste streams. (authors)

  10. Handling Cyber Security Alerts and Advisories and Reporting Cyber Security Incidents

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2002-03-18

    To establish Department of Energy (DOE) requirements and responsibilities for reporting cyber security incidents involving classified and unclassified systems and responding to cyber security alerts and advisories; and to implement requirements of DOE N 205.1, Unclassified Cyber Security Program, and DOE M 471.2-2, Classified Information Systems Security Manual. DOE N 205.13, dated 7-6-04, extends this notice until 7-6-05. Cancels DOE M 471.2-2, Chapter III, section 8.

  11. Catastrophic Incident Recovery: Long-Term Recovery from an Anthrax Event Symposium

    SciTech Connect (OSTI)

    Lesperance, Ann M.

    2008-06-30

    On March 19, 2008, policy makers, emergency managers, and medical and Public Health officials convened in Seattle, Washington, for a workshop on Catastrophic Incident Recovery: Long-Term Recovery from an Anthrax Event. The day-long symposium was aimed at generating a dialogue about restoration and recovery through a discussion of the associated challenges that impact entire communities, including people, infrastructure, and critical systems.

  12. Nucleation of diindenoperylene and pentacene at thermal and hyperthermal incident kinetic energies

    SciTech Connect (OSTI)

    Kish, Edward R.; Desai, Tushar V.; Greer, Douglas R.; Engstrom, James R.; Woll, Arthur R.

    2015-05-15

    The authors have examined the nucleation of diindenoperylene (DIP) on SiO{sub 2} employing primarily atomic force microscopy and focusing on the effect of incident kinetic energy employing both thermal and supersonic sources. For all incident kinetic energies examined (E{sub i} = 0.09–11.3 eV), the nucleation of DIP is homogeneous and the dependence of the maximum island density on the growth rate is described by a power law. A critical nucleus of approximately two molecules is implicated by our data. A re-examination of the nucleation of pentacene on SiO{sub 2} gives the same major result that the maximum island density is determined by the growth rate, and it is independent of the incident kinetic energy. These observations are readily understood by factoring in the size of the critical nucleus in each case, and the island density, which indicates that diffusive transport of molecules to the growing islands dominate the dynamics of growth in the submonolayer regime.

  13. Advanced grazing-incidence techniques for modern soft-matter materials analysis

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Hexemer, Alexander; Müller-Buschbaum, Peter

    2015-01-01

    The complex nano-morphology of modern soft-matter materials is successfully probed with advanced grazing-incidence techniques. Based on grazing-incidence small- and wide-angle X-ray and neutron scattering (GISAXS, GIWAXS, GISANS and GIWANS), new possibilities arise which are discussed with selected examples. Due to instrumental progress, highly interesting possibilities for local structure analysis in this material class arise from the use of micro- and nanometer-sized X-ray beams in micro- or nanofocused GISAXS and GIWAXS experiments. The feasibility of very short data acquisition times down to milliseconds creates exciting possibilities forin situandin operandoGISAXS and GIWAXS studies. Tuning the energy of GISAXS and GIWAXS in themore » soft X-ray regime and in time-of flight GISANS allows the tailoring of contrast conditions and thereby the probing of more complex morphologies. In addition, recent progress in software packages, useful for data analysis for advanced grazing-incidence techniques, is discussed.« less

  14. Advanced grazing-incidence techniques for modern soft-matter materials analysis

    SciTech Connect (OSTI)

    Hexemer, Alexander; Müller-Buschbaum, Peter

    2015-01-01

    The complex nano-morphology of modern soft-matter materials is successfully probed with advanced grazing-incidence techniques. Based on grazing-incidence small- and wide-angle X-ray and neutron scattering (GISAXS, GIWAXS, GISANS and GIWANS), new possibilities arise which are discussed with selected examples. Due to instrumental progress, highly interesting possibilities for local structure analysis in this material class arise from the use of micro- and nanometer-sized X-ray beams in micro- or nanofocused GISAXS and GIWAXS experiments. The feasibility of very short data acquisition times down to milliseconds creates exciting possibilities forin situandin operandoGISAXS and GIWAXS studies. Tuning the energy of GISAXS and GIWAXS in the soft X-ray regime and in time-of flight GISANS allows the tailoring of contrast conditions and thereby the probing of more complex morphologies. In addition, recent progress in software packages, useful for data analysis for advanced grazing-incidence techniques, is discussed.

  15. Spatial Estimation of Populations at Risk from Radiological Dispersion Device Terrorism Incidents

    SciTech Connect (OSTI)

    Regens, J.L.; Gunter, J.T.

    2008-07-01

    Delineation of the location and size of the population potentially at risk of exposure to ionizing radiation is one of the key analytical challenges in estimating accurately the severity of the potential health effects associated with a radiological terrorism incident. Regardless of spatial scale, the geographical units for which population data commonly are collected rarely coincide with the geographical scale necessary for effective incident management and medical response. This paper identifies major government and commercial open sources of U.S. population data and presents a GIS-based approach for allocating publicly available population data, including age distributions, to geographical units appropriate for planning and implementing incident management and medical response strategies. In summary: The gravity model offers a straight-forward, empirical tool for estimating population flows, especially when geographical areas are relatively well-defined in terms of accessibility and spatial separation. This is particularly important for several reasons. First, the spatial scale for the area impacted by a RDD terrorism event is unlikely to match fully the spatial scale of available population data. That is, the plume spread typically will not uniformly overlay the impacted area. Second, the number of people within the impacted area varies as a function whether an attack occurs during the day or night. For example, the population of a central business district or industrial area typically is larger during the day while predominately residential areas have larger night time populations. As a result, interpolation techniques that link population data to geographical units and allocate those data based on time-frame at a spatial scale that is relevant to enhancing preparedness and response. The gravity model's main advantage is that it efficiently allocates readily available, open source population data to geographical units appropriate for planning and implementing

  16. Evaluation of the Reanalysis Surface Incident Shortwave Radiation Products from NCEP, ECMWF, GSFC, and JMA Using Satellite and Surface Observations

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Zhang, Xiaotong; Liang, Shunlin; Wang, Guoxin; Yao, Yunjun; Jiang, Bo; Cheng, Jie

    2016-03-10

    Solar radiation incident at the Earth’s surface (Rs) is an essential component of the total energy exchange between the atmosphere and the surface. Reanalysis data have been widely used, but a comprehensive validation using surface measurements is still highly needed. In this study, we evaluated the Rs estimates from six current representative global reanalyses (NCEP–NCAR, NCEP-DOE; CFSR; ERA-Interim; MERRA; and JRA-55) using surface measurements from different observation networks [GEBA; BSRN; GC-NET; Buoy; and CMA] (674 sites in total) and the Earth’s Radiant Energy System (CERES) EBAF product from 2001 to 2009. The global mean biases between the reanalysis Rs andmore » surface measurements at all sites ranged from 11.25 W/m2 to 49.80 W/m2. Comparing with the CERES-EBAF Rs product, all the reanalyses overestimate Rs, except for ERA-Interim, with the biases ranging from 2.98 W/m2 to 21.97 W/m2 over the globe. It was also found that the biases of cloud fraction (CF) in the reanalyses caused the overestimation of Rs. Lastly, ffter removing the averaged bias of CERES-EBAF, weighted by the area of the latitudinal band, a global annual mean Rs values of 184.6 W/m2, 180.0 W/m2, and 182.9 W/m2 were obtained over land, ocean, and the globe, respectively.« less

  17. What Causes Electron Heat Loss in Fusion Plasma?

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Causes Heat Loss in Fusion Plasmas? What Causes Electron Heat Loss in Fusion Plasma? 3D ... but one of the most basic is heating plasma-hot gas composed of electrons and charged ...

  18. Scientists say climate change could cause a 'massive' tree die...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Climate change could cause a 'massive' tree die-off in the U.S. Southwest Scientists say climate change could cause a 'massive' tree die-off in the U.S. Southwest In a troubling ...

  19. Second harmonic generation by propagation of a p-polarized obliquely incident laser beam in underdense plasma

    SciTech Connect (OSTI)

    Jha, Pallavi; Agrawal, Ekta

    2014-05-15

    An analytical study of second harmonic generation due to interaction an intense, p-polarized laser beam propagating obliquely in homogeneous underdense plasma, in the mildly relativistic regime, has been presented. The efficiency of the second harmonic radiation as well as its detuning length has been obtained and their variation with the angle of incidence is analyzed. It is shown that, for a given plasma electron density, the second harmonic efficiency increases with the angle of incidence while the detuning length decreases. The second harmonic amplitude vanishes at normal incidence of the laser beam.

  20. Characterization and Isolation of Constituents Causing Red Coloration in

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Desert Arroyo Seepage Water | Department of Energy Characterization and Isolation of Constituents Causing Red Coloration in Desert Arroyo Seepage Water Characterization and Isolation of Constituents Causing Red Coloration in Desert Arroyo Seepage Water Characterization and Isolation of Constituents Causing Red Coloration in Desert Arroyo Seepage Water Characterization and Isolation of Constituents Causing Red Coloration in Desert Arroyo Seepage Water (863.48 KB) More Documents &

  1. Incidence of Leukoencephalopathy After Whole-Brain Radiation Therapy for Brain Metastases

    SciTech Connect (OSTI)

    Ebi, Junko; Sato, Hisashi; Nakajima, Masaru; Shishido, Fumio

    2013-04-01

    Purpose: To evaluate the incidence of leukoencephalopathy after whole-brain radiation therapy (WBRT) in patients with brain metastases. Methods and Materials: We retrospectively reviewed 111 patients who underwent WBRT for brain metastases from April 2001 through March 2008 and had evaluable computed tomography (CT) and/or magnetic resonance imaging (MRI) at least 1 month after completion of WBRT. We evaluated the leukoencephalopathy according to the Common Terminology Criteria for Adverse Events, version 3.0. The patients who had brain tumor recurrence after WBRT were censored at the last follow-up CT or MRI without recurrence. To evaluate the risk factors for leukoencephalopathy, bivariate analysis was performed using a logistic regression analysis adjusted for follow-up time. Factors included in the analysis were age, gender, dose fractionation, 5-fluorouracil, methotrexate, cisplatin, and other chemotherapeutic agents. Results: The median age of the 111 patients was 60.0 years (range, 23-89 years). The median follow-up was 3.8 months (range, 1.0-38.1 months). Leukoencephalopathy developed in 23 of the 111 patients. Grades 1, 2, and 3 were observed in 8, 7, and 8 patients, respectively. The incidence was 34.4% (11 of 32), 42.9% (6 of 14), 66.7% (2 of 3), and 100% (2 of 2) of the patients who were followed up for ≥6, ≥12, ≥24, and ≥36 months, respectively. In the bivariate analysis, older age (≥65 years) was significantly correlated with higher risk of leukoencephalopathy (odds ratio 3.31; 95% confidence interval 1.15-9.50; P=.03). Conclusions: The incidence of leukoencephalopathy after WBRT was 34.4% with ≥6 months follow-up, and increased with longer follow-up. Older age was a significant risk factor. The schedule of WBRT for patients with brain metastases should be carefully determined, especially for favorable patients.

  2. Incidence, Risks, and Sequelae of Posterior Fossa Syndrome in Pediatric Medulloblastoma

    SciTech Connect (OSTI)

    Korah, Mariam P.; Esiashvili, Natia; Mazewski, Claire M.; Hudgins, Roger J.; Tighiouart, Mourad; Janss, Anna J.; Schwaibold, Frederick P.; Crocker, Ian R.; Curran, Walter J.; Marcus, Robert B.

    2010-05-01

    Purpose: To investigate the incidence, risks, severity, and sequelae of posterior fossa syndrome (PFS) in children with medulloblastoma. Methods and Materials: Between 1990 and 2007, 63 children with medulloblastoma at Emory University and Children's Healthcare of Atlanta were treated with craniectomy followed by radiation. Fifty-one patients were assigned to a standard-risk group, and 12 patients were assigned to a high-risk group. Five patients had <1.5-cm{sup 2} residual tumor, 4 had >=1.5-cm{sup 2} residual tumor, and the remainder had no residual tumor. Eleven patients had disseminated disease. Patients received craniospinal irradiation at a typical dose of 23.4 Gy or 36 Gy for standard- or high-risk disease, respectively. The posterior fossa was given a total dose of 54 or 55.8 Gy. Nearly all patients received chemotherapy following cooperative group protocols. Results: Median follow-up was 7 years. PFS developed in 18 patients (29%). On univariate analysis, brainstem invasion, midline tumor location, younger age, and the absence of radiographic residual tumor were found to be predictors of PFS; the last two variables remained significant on multivariate analysis. From 1990 to 2000 and from 2001 to 2007, the proportions of patients with no radiographic residual tumor were 77% and 94%, respectively. During the same eras, the proportions of patients with PFS were 17% and 39%. Only 4 patients had complete recovery at last follow-up. Conclusions: The incidence of PFS increased in the latter study period and is proportional to more aggressive surgery. Children with midline tumors exhibiting brainstem invasion are at increased risk. With the increased incidence of PFS and the permanent morbidity in many patients, the risks and benefits of complete tumor removal in all patients need to be reexamined.

  3. Electron emission induced by resonant coherent ion-surface interaction at grazing incidence

    SciTech Connect (OSTI)

    Garcia de Abajo, F.J. ); Ponce, V.H. ); Echenique, P.M. )

    1992-10-19

    A new spectroscopy based on the resonant coherently induced electron loss to the continuum in ion-surface scattering under grazing incidence is proposed. A series of peaks, corresponding to the energy differences determined by the resonant interaction with the rows of atoms in the surface, is predicted to appear in the energy distribution of electrons emitted from electronic states bound to the probe. Calculations for MeV He{sup +} ions scattered at a W(001) surface along the {l angle}100{r angle} direction with a glancing angle of 0--2 mrad show a total yield close to 1.

  4. Fact Sheet Investigation of Incident at Waste Isolation Pilot Plant by Technical Assessment Team

    Broader source: Energy.gov [DOE]

    On February 14, 2014, an incident in Panel 7 Room 7 (P7R7) of the Waste Isolation Pilot Plant (WIPP) underground repository resulted in the release of radioactive material into the environment and contaminated 21 people with low-level radioactivity. The Technical Assessment Team (TAT) concluded that one drum, Drum 68660, was the source of radioactive contamination released during the February 14, 2014, radiological event at WIPP. The contents of Drum 68660 were chemically incompatible, and the drum breached as a result of internal chemical reactions.

  5. Reducing the Probability of Incidents Through Behavior-Based Safety -- An Anomaly or Not?

    SciTech Connect (OSTI)

    Turek, John A

    2002-07-23

    Reducing the probability of incidents through Behavior-Based Safety--an anomaly or not? Can a Behavior-Based Safety (BBS) process reduce the probability of an employee sustaining a work-related injury or illness? This presentation describes the actions taken to implement a sustainable BBS process and evaluates its effectiveness. The BBS process at the Stanford Linear Accelerator Center used a pilot population of national laboratory employees to: Achieve employee and management support; Reduce the probability of employees' sustaining work-related injuries and illnesses; and Provide support for additional funding to expand within the laboratory.

  6. Reducing the Probability of Incidents Through Behavior-Based Safety -- An Anomaly or Not?

    SciTech Connect (OSTI)

    Turek, John A

    2002-07-23

    Reducing the probability of incidents through Behavior-Based Safety-an anomaly or not? Can a Behavior-Based Safety (BBS) process reduce the probability of an employee sustaining a work-related injury or illness? This presentation describes the actions taken to implement a sustainable BBS process and evaluates its effectiveness. The BBS process at the Stanford Linear Accelerator Center used a pilot population of national laboratory employees to: Achieve employee and management support; Reduce the probability of employees' sustaining work-related injuries and illnesses; and Provide support for additional funding to expand within the laboratory.

  7. Electron emission induced by resonant coherent interaction in ion-surface scattering at grazing incidence

    SciTech Connect (OSTI)

    Garcia de Abajo, F.J. ); Ponce, V.H.; Echenique, P.M. )

    1994-01-15

    The resonant coherent interaction of an ion with an oriented crystal surface, under grazing-incidence conditions with respect to a special direction of the crystal, gives rise to electron loss to the continuum from electronic bound states of the ion. The calculations presented below predict large probabilities for electron emission due to this mechanism. The electrons are emitted with well defined energies, expressed in terms of the condition of resonance. Furthermore, the emission takes place around certain preferential directions, which are determined by both the latter condition and the symmetry of the surface lattice. Our calculations for MeV He[sup +] ions scattered at a W(001) surface along the [l angle]100[r angle] direction with glancing angle of 0--2 mrad indicate a yield of emission close to 1. Using heavier projectiles, one obtains smaller yields, but still large enough to be measurable in some cases (e.g., [approx]0.9 for 53 MeV B[sup 4+] and an angle of incidence of 1 mrad). Besides, the initial bound state is energy shifted due to the interaction with both the crystal potential and the velocity-dependent image potential. This results in a slight shift of the peaks of emission, which suggests a possible spectroscopy for analyzing the dynamical interaction of electronic bound states with solid surfaces.

  8. Electron-impact excitation of xenon at incident energies between 15 and 80 eV

    SciTech Connect (OSTI)

    Filipovic-acute-accent, D.; Marinkovic-acute-accent, B.; Pejcev, V.; Vuskovic-acute-accent, a.L.

    1988-01-15

    Normalized, absolute differential cross sections (DCS's) have been measured for the 20 lowest electronic states of xenon. Incident electron energies were 15, 20, 30, and 80 eV and the scattering angles ranged from 5/sup 0/ to 150/sup 0/. The energy resolution was 40 meV. Absolute elastic DCS's have been obtained by normalizing the relative values to the recently published absolute elastic DCS's by Register et al. (J. Phys. B 19, 1685 (1986)). Elastic-to-inelastic intensity ratios, at different incident energies for the 6s((3/2)/sub 1/ state were determined. These ratios were utilized as secondary standards to establish the absolute scale for the other inelastic processes in accordance with intensity ratios of lines in energy-loss spectra. The absolute inelastic DCS's were extrapolated to 0/sup 0/ and 180/sup 0/ and integrated to yield the integral cross sections (ICS's). A comparison of the present DCS's with the only available measurements at 20 eV impact energy shows satisfactory agreement in shape but considerable difference in absolute value.

  9. Technical Review of Law Enforcement Standards and Guides Relative to Incident Management

    SciTech Connect (OSTI)

    Stenner, Robert D.; Salter, R.; Stanton, J. R.; Fisher, D.

    2009-03-24

    In an effort to locate potential law enforcement-related standards that support incident management, a team from the Pacific Northwest National Laboratory (PNNL) contacted representatives from the National Institute of Standards-Office of Law Enforcement Standards (NIST-OLES), National Institute of Justice (NIJ), Federal Bureau of Investigation (FBI), Secret Service, ASTM International committees that have a law enforcement focus, and a variety of individuals from local and regional law enforcement organizations. Discussions were held with various state and local law enforcement organizations. The NIJ has published several specific equipment-related law enforcement standards that were included in the review, but it appears that law enforcement program and process-type standards are developed principally by organizations that operate at the state and local level. Input is provided from state regulations and codes and from external non-government organizations (NGOs) that provide national standards. The standards that are adopted from external organizations or developed independently by state authorities are available for use by local law enforcement agencies on a voluntary basis. The extent to which they are used depends on the respective jurisdictions involved. In some instances, use of state and local disseminated standards is mandatory, but in most cases, use is voluntary. Usually, the extent to which these standards are used appears to depend on whether or not jurisdictions receive certification from a “governing” entity due to their use and compliance with the standards. In some cases, these certification-based standards are used in principal but without certification or other compliance monitoring. In general, these standards appear to be routinely used for qualification, selection for employment, and training. In these standards, the term “Peace Officer” is frequently used to refer to law enforcement personnel. This technical review of national law

  10. Malfunctions of Implantable Cardiac Devices in Patients Receiving Proton Beam Therapy: Incidence and Predictors

    SciTech Connect (OSTI)

    Gomez, Daniel R., E-mail: dgomez@mdanderson.org [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Poenisch, Falk [Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Pinnix, Chelsea C. [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Sheu, Tommy [Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Chang, Joe Y. [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Memon, Nada [Department of Cardiology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Mohan, Radhe [Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Rozner, Marc A. [Department of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Dougherty, Anne H. [Department of Cardiology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States)

    2013-11-01

    Purpose: Photon therapy has been reported to induce resets of implanted cardiac devices, but the clinical sequelae of treating patients with such devices with proton beam therapy (PBT) are not well known. We reviewed the incidence of device malfunctions among patients undergoing PBT. Methods and Materials: From March 2009 through July 2012, 42 patients with implanted cardiac implantable electronic devices (CIED; 28 pacemakers and 14 cardioverter-defibrillators) underwent 42 courses of PBT for thoracic (23, 55%), prostate (15, 36%), liver (3, 7%), or base of skull (1, 2%) tumors at a single institution. The median prescribed dose was 74 Gy (relative biological effectiveness; range 46.8-87.5 Gy), and the median distance from the treatment field to the CIED was 10 cm (range 0.8-40 cm). Maximum proton and neutron doses were estimated for each treatment course. All CIEDs were checked before radiation delivery and monitored throughout treatment. Results: Median estimated peak proton and neutron doses to the CIED in all patients were 0.8 Gy (range 0.13-21 Gy) and 346 Sv (range 11-1100 mSv). Six CIED malfunctions occurred in 5 patients (2 pacemakers and 3 defibrillators). Five of these malfunctions were CIED resets, and 1 patient with a defibrillator (in a patient with a liver tumor) had an elective replacement indicator after therapy that was not influenced by radiation. The mean distance from the proton beam to the CIED among devices that reset was 7.0 cm (range 0.9-8 cm), and the mean maximum neutron dose was 655 mSv (range 330-1100 mSv). All resets occurred in patients receiving thoracic PBT and were corrected without clinical incident. The generator for the defibrillator with the elective replacement indicator message was replaced uneventfully after treatment. Conclusions: The incidence of CIED resets was about 20% among patients receiving PBT to the thorax. We recommend that PBT be avoided in pacing-dependent patients and that patients with any type of CIED receiving

  11. ROOT CAUSE ANALYSIS AND CORRECTIVE ACTION PLAN CLOSURE REPORT | Department

    Energy Savers [EERE]

    of Energy ROOT CAUSE ANALYSIS AND CORRECTIVE ACTION PLAN CLOSURE REPORT ROOT CAUSE ANALYSIS AND CORRECTIVE ACTION PLAN CLOSURE REPORT The Department conducted a root cause analysis (RCA) workshop on October 16-17, 2007, to identify the systemic challenges of planning and managing DOE projects. During the workshop participants singled out 143 issues, which they consolidated and prioritized. The Department published the results of the RCA workshop in an April 2008 DOE report entitled, U.S.

  12. Root Cause Analysis Report In Response to Condition Report 5223...

    Energy Savers [EERE]

    5223 Regarding Emails Suggesting Noncompliance with Quality Assurance Requirements Root Cause Analysis Report In Response to Condition Report 5223 Regarding Emails Suggesting ...

  13. Extreme pressure causes osmium to change state of matter | Argonne...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    group of researchers have demonstrated that ultra-high pressures cause core electrons to interplay, which results in experimentally observed anomalies in the compression...

  14. Sandia Energy - Geomechanical Modeling to Investigate the Cause...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Geomechanical Modeling to Investigate the Cause of Oil Leaks in Wellbores at Big Hill Strategic Petroleum Reserve Home Highlights - HPC Geomechanical Modeling to Investigate the...

  15. Hydrogen Embrittlement of Pipeline Steels: Causes and Remediation...

    Broader source: Energy.gov (indexed) [DOE]

    Barriers: Hydrogen embrittlement of pipelines and remediation (mixing with water vapor?) ... Enable a Carbon-Neutral Energy Economy Hydrogen Embrittlement of Pipeline Steels: Causes ...

  16. Researchers Achieve Breakthrough in Solving Leading Cause of...

    Broader source: Energy.gov (indexed) [DOE]

    cause of wind turbine gearbox failures, known as white-etch cracks or axial cracks. ... improve turbine reliability and reduce overall wind plant maintenance costs." ...

  17. Trending and root cause analysis of TWRS radiological problem reports

    SciTech Connect (OSTI)

    Brown, R.L.

    1997-07-31

    This document provides a uniform method for trending and performing root cause analysis for radiological problem reports at Tank Waste Remediation System (TWRS).

  18. Incident angle insensitive tunable multichannel perfect absorber consisting of nonlinear plasma and matching metamaterials

    SciTech Connect (OSTI)

    Kong, Xiang-kun; Liu, Shao-Bin Bian, Bo-rui; Chen, Chen; Zhang, Hai-feng

    2014-12-15

    A novel, compact, and multichannel nonreciprocal absorber through a wave tunneling mechanism in epsilon-negative and matching metamaterials is theoretically proposed. Nonreciprocal absorption properties are acquired via the coupling together of evanescent and propagating waves in an asymmetric configuration, constituted of nonlinear plasma alternated with matching metamaterial. The absorption channel number can be adjusted by changing the periodic number. Due to the positive feedback between nonlinear permittivity of plasma and the inner electric field, bistable absorption and reflection are achieved. Moreover, compared with some truncated photonic crystal or multilayered designs proposed before, our design is more compact and independent of incident angle or polarization. This kind of multilayer structure offers additional opportunities to design novel omnidirectional electromagnetic wave absorbers.

  19. Light trapping for emission from a photovoltaic cell under normally incident monochromatic illumination

    SciTech Connect (OSTI)

    Takeda, Yasuhiko Iizuka, Hideo; Mizuno, Shintaro; Hasegawa, Kazuo; Ichikawa, Tadashi; Ito, Hiroshi; Kajino, Tsutomu; Ichiki, Akihisa; Motohiro, Tomoyoshi

    2014-09-28

    We have theoretically demonstrated a new light-trapping mechanism to reduce emission from a photovoltaic (PV) cell used for a monochromatic light source, which improves limiting conversion efficiency determined by the detailed balance. A multilayered bandpass filter formed on the surface of a PV cell has been found to prevent the light generated inside by radiative recombination from escaping the cell, resulting in a remarkable decrease of the effective solid angle for the emission. We have clarified a guide to design a suitable configuration of the bandpass filter and achieved significant reduction of the emission. The resultant gain in monochromatic conversion efficiency in the radiative limit due to the optimally designed 18-layerd bandpass filters is as high as 6% under normally incident 1064 nm illumination of 10 mW/cm~ 1 kW/cm, compared with the efficiency for the perfect anti-reflection treatment to the surface of a conventional solar cell.

  20. Tensions in collaborative cyber security and how they affect incident detection and response

    SciTech Connect (OSTI)

    Fink, Glenn A.; McKinnon, Archibald D.; Clements, Samuel L.; Frincke, Deborah A.

    2009-12-01

    Security often requires collaboration, but when multiple stakeholders are involved, it is typical for their priorities to differ or even conflict with one another. In todays increasingly networked world, cyber security collaborations may span organizations and countries. In this chapter, we address collaboration tensions, their effects on incident detection and response, and how these tensions may potentially be resolved. We present three case studies of collaborative cyber security within the U.S. government and discuss technical, social, and regulatory challenges to collaborative cyber security. We suggest possible solutions, and present lessons learned from conflicts. Finally, we compare collaborative solutions from other domains and apply them to cyber security collaboration. Although we concentrate our analysis on collaborations whose purpose is to achieve cyber security, we believe that this work applies readily to security tensions found in collaborations of a general nature as well.

  1. Fractures of the Sacrum After Chemoradiation for Rectal Carcinoma: Incidence, Risk Factors, and Radiographic Evaluation

    SciTech Connect (OSTI)

    Kim, Han Jo; Boland, Patrick J.; Meredith, Dennis S.; Lis, Eric; Zhang Zhigang; Shi Weiji; Yamada, Yoshiya J.; Goodman, Karyn A.

    2012-11-01

    Purpose: Sacral insufficiency fractures after adjuvant radiation for rectal carcinoma can present similarly to recurrent disease. As a complication associated with pelvic radiation, it is important to be aware of the incidence and risk factors associated with sacral fractures in the clinical assessment of these patients. Methods and Materials: Between 1998 and 2007, a total of 582 patients with locally advanced rectal carcinoma received adjuvant chemoradiation and surgical excision. Of these, 492 patients had imaging studies available for review. Hospital records and imaging studies from all 492 patients were retrospectively evaluated to identify risk factors associated with developing a sacral insufficiency fracture. Results: With a median follow-up time of 3.5 years, the incidence of sacral fractures was 7.1% (35/492). The 4-year sacral fracture free rate was 0.91. Univariate analysis showed that increasing age ({>=}60 vs. <60 years), female sex, and history of osteoporosis were significantly associated with shorter time to sacral fracture (P=.01, P=.004, P=.001, respectively). There was no significant difference in the time to sacral fracture for patients based on stage, radiotherapy dose, or chemotherapy regimen. Multivariate analysis showed increasing age ({>=}60 vs. <60 years, hazard ratio [HR] = 2.50, 95% confidence interval [CI] = 1.22-5.13, P=.01), female sex (HR = 2.64, CI = 1.29-5.38, P=.008), and history of osteoporosis (HR = 3.23, CI = 1.23-8.50, P=.02) were independent risk factors associated with sacral fracture. Conclusions: Sacral insufficiency fractures after pelvic radiation for rectal carcinoma occur more commonly than previously described. Independent risk factors associated with fracture were osteoporosis, female sex, and age greater than 60 years.

  2. Incidence of Second Malignancies Among Patients Treated With Proton Versus Photon Radiation

    SciTech Connect (OSTI)

    Chung, Christine S.; Yock, Torunn I.; Nelson, Kerrie; Xu, Yang; Keating, Nancy L.; Tarbell, Nancy J.

    2013-09-01

    Purpose: Proton radiation, when compared with photon radiation, allows delivery of increased radiation dose to the tumor while decreasing dose to adjacent critical structures. Given the recent expansion of proton facilities in the United States, the long-term sequelae of proton therapy should be carefully assessed. The objective of this study was to compare the incidence of second cancers in patients treated with proton radiation with a population-based cohort of matched patients treated with photon radiation. Methods and Materials: We performed a retrospective cohort study of 558 patients treated with proton radiation from 1973 to 2001 at the Harvard Cyclotron in Cambridge, MA and 558 matched patients treated with photon therapy in the Surveillance, Epidemiology, and End Results (SEER) Program cancer registry. Patients were matched by age at radiation treatment, sex, year of treatment, cancer histology, and site. The main outcome measure was the incidence of second malignancies after radiation. Results: We matched 558 proton patients with 558 photon patients from the Surveillance, Epidemiology, and End Results registry. The median duration of follow-up was 6.7 years (interquartile range, 7.4) and 6.0 years (interquartile range, 9.3) in the proton and photon cohorts, respectively. The median age at treatment was 59 years in each cohort. Second malignancies occurred in 29 proton patients (5.2%) and 42 photon patients (7.5%). After we adjusted for sex, age at treatment, primary site, and year of diagnosis, proton therapy was not associated with an increased risk of second malignancy (adjusted hazard ratio, 0.52 [95% confidence interval, 0.32-0.85]; P=.009). Conclusions: The use of proton radiation therapy was not associated with a significantly increased risk of secondary malignancies compared with photon therapy. Longer follow-up of these patients is needed to determine if there is a significant decrease in second malignancies. Given the limitations of the study

  3. Root Causes of Component Failures Program: Methods and applications

    SciTech Connect (OSTI)

    Satterwhite, D G; Cadwallader, L C; Vesely, W E; Meale, B M

    1986-12-01

    This report contains information pertaining to definitions, methodologies, and applications of root cause analysis. Of specific interest, and highlighted throughout the discussion, are applications pertaining to current and future Nuclear Regulatory Commission (NRC) light water reactor safety programs. These applications are discussed in view of addressing specific program issues under NRC consideration and reflect current root cause analysis capabilities.

  4. National Incident Management System (NIMS) Standards Review Panel Workshop Summary Report

    SciTech Connect (OSTI)

    Stenner, Robert D.; Kirk, Jennifer L.; Stanton, James R.; Shebell, Peter; Schwartz, Deborah S.; Judd, Kathleen S.; Gelston, Gariann M.

    2006-02-07

    The importance and need for full compliant implementation of NIMS nationwide was clearly demonstrated during the Hurricane Katrina event, which was clearly expressed in Secretary Chertoff's October 4, 2005 letter addressed to the State's governors. It states, ''Hurricane Katrina was a stark reminder of how critical it is for our nation to approach incident management in a coordinated, consistent, and efficient manner. We must be able to come together, at all levels of government, to prevent, prepare for, respond to, and recover from any emergency or disaster. Our operations must be seamless and based on common incident management doctrine, because the challenges we face as a nation are far greater than capabilities of any one jurisdiction.'' The NIMS is a system/architecture for organizing response on a ''national'' level. It incorporations ICS as a main component of that structure (i.e., it institutionalizes ICS in NIMS). In a paper published on the NIMS Website, the following statements were made: ''NIMS represents a core set of doctrine, principles, terminology, and organizational processes to enable effective, efficient and collaborative incident management at all levels. To provide the framework for interoperability and compatibility, the NIMS is based on a balance between flexibility and standardization.'' Thus the NIC is challenged with the need to adopt quality SDO generated standards to support NIMS compliance, but in doing so maintain the flexibility necessary so that response operations can be tailored for the specific jurisdictional and geographical needs across the nation. In support of this large and complex challenge facing the NIC, the Pacific Northwest National Laboratory (PNNL) was asked to provide technical support to the NIC, through their DHS Science and Technology ? Standards Portfolio Contract, to help identify, review, and develop key standards for NIMS compliance. Upon examining the challenge, the following general process appears to be a

  5. A reevaluation of cancer incidence near the Three Mile Island nuclear plant: The collision of evidence and assumptions

    SciTech Connect (OSTI)

    Wing, S.; Richardson, D.; Armstrong, D.; Crawford-Brown, D.

    1997-01-01

    Previous studies concluded that there was no evidence that the 1979 nuclear accident at Three Mile Island (TMI) affected cancer incidence in the surrounding area; however, there were logical and methodological problems in earlier reports that led us to reconsider data previously collected. A 10-mile area around TMI was divided into 69 study tracts, which were assigned radiation dose estimates based on radiation readings and models of atmospheric dispersion. Incident cancers from 1975 to 1985 were ascertained from hospital records and assigned to study tracts. Associations between accident doses and incidence rates of leukemia, lung cancer, and all cancer were assessed using relative dose estimates calculated by the earlier investigators. Adjustments were made for age, sex, socioeconomic characteristics, and preaccident variation in incidence. Considering a 2-year latency, the estimated percent increase per dose unit {plus_minus} standard error was 0.020 {plus_minus} 0.012 for all cancer, 0.082 {plus_minus} 0.032 for lung cancer, and 0.116 {plus_minus} 0.067 for leukemia. Adjustment for socioeconomic variables increased the estimates to 0.034 {plus_minus} 0.013, 0.103 {plus_minus} 0.035, and 0.139 {plus_minus} 0.073 for all cancer, lung cancer, and leukemia, respectively. Associations were generally larger considering a 5-year latency, but were based on smaller numbers of cases. Results support the hypothesis that radiation doses are related to increased cancer incidence around TMI. The analysis avoids medical detection bias, but suffers from inaccurate dose classification; therefore, results may underestimate the magnitude of the association between radiation and cancer incidence. These associations would not be expected, based on previous estimates of near-background levels of radiation exposure following the accident. 35 refs., 3 tabs.

  6. MO-G-BRE-09: Validating FMEA Against Incident Learning Data: A Study in Stereotactic Body Radiation Therapy

    SciTech Connect (OSTI)

    Yang, F; Cao, N; Young, L; Howard, J; Sponseller, P; Logan, W; Arbuckle, T; Korssjoen, T; Meyer, J; Ford, E

    2014-06-15

    Purpose: Though FMEA (Failure Mode and Effects Analysis) is becoming more widely adopted for risk assessment in radiation therapy, to our knowledge it has never been validated against actual incident learning data. The objective of this study was to perform an FMEA analysis of an SBRT (Stereotactic Body Radiation Therapy) treatment planning process and validate this against data recorded within an incident learning system. Methods: FMEA on the SBRT treatment planning process was carried out by a multidisciplinary group including radiation oncologists, medical physicists, and dosimetrists. Potential failure modes were identified through a systematic review of the workflow process. Failure modes were rated for severity, occurrence, and detectability on a scale of 1 to 10 and RPN (Risk Priority Number) was computed. Failure modes were then compared with historical reports identified as relevant to SBRT planning within a departmental incident learning system that had been active for two years. Differences were identified. Results: FMEA identified 63 failure modes. RPN values for the top 25% of failure modes ranged from 60 to 336. Analysis of the incident learning database identified 33 reported near-miss events related to SBRT planning. FMEA failed to anticipate 13 of these events, among which 3 were registered with severity ratings of severe or critical in the incident learning system. Combining both methods yielded a total of 76 failure modes, and when scored for RPN the 13 events missed by FMEA ranked within the middle half of all failure modes. Conclusion: FMEA, though valuable, is subject to certain limitations, among them the limited ability to anticipate all potential errors for a given process. This FMEA exercise failed to identify a significant number of possible errors (17%). Integration of FMEA with retrospective incident data may be able to render an improved overview of risks within a process.

  7. Realizing thin electromagnetic absorbers for wide incidence angles from commercially available planar circuit materials

    SciTech Connect (OSTI)

    Glover, Brian B; Whites, Kieth W; Radway, Matthew J

    2009-01-01

    In this study, recent work on engineering R-card surface resistivity with printed metallic patterns is extended to the design of thin electromagnetic absorbers. Thin electromagnetic absorbers for wide incidence angles and both polarizations have recently been computationally verified by Luukkonen et al.. These absorbers are analytically modeled high-impedance surfaces with capacitive arrays of square patches implemented with relatively high dielectric constant and high loss substrate. However, the advantages provided by the accurate analytical model are largely negated by the need to obtain high dielectric constant material with accurately engineered loss. Fig. I(c) illustrates full-wave computational results for an absorber without vias engineered as proposed by Luukkonen et al.. Unique values for the dielectric loss are required for different center frequencies. Parameters for the capacitive grid are D=5.0 mm and w=O.l mm for a center frequency of 3.36 GHz. The relative permittivity and thickness is 9.20(1-j0.234) and 1=3.048 mm. Consider a center frequency of5.81 GHz and again 1=3.048 mm, the required parameters for the capacitive grid are D=2.0 mm and w=0.2 mm where the required relative permittivity is now 9.20(1-j0.371) Admittedly, engineered dielectrics are themselves a historically interesting and fruitful research area which benefits today from advances in monolithic fabrication using direct-write of dielectrics with nanometer scale inclusions. However, our objective in the present study is to realize the advantages of the absorber proposed by Luukkonen et al. without resort to engineered lossy dielectrics. Specifically we are restricted to commercially available planer circuit materials without use of in-house direct-write technology or materials engineering capability. The materials considered here are TMM 10 laminate with (35 {mu}lm copper cladding with a complex permittivity 9.20-j0.0022) and Ohmegaply resistor conductor material (maximum 250 {Omega

  8. Interfacial Electron-Phonon Coupling as the Cause of Enhanced...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Interfacial Electron-Phonon Coupling as the Cause of Enhanced Tc in Single-layer FeSe Films on SrTiO3 Friday, February 27, 2015 In the past several years, multiple studies have...

  9. New screening process for potentially cancer causing chemicals

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    New screening process for potentially cancer causing chemicals Click to share on Facebook (Opens in new window) Click to share on Twitter (Opens in new window) Click to share on ...

  10. Scientists Assess Damage Caused by Earthquake near Amchitka

    Broader source: Energy.gov [DOE]

    Contractor scientists for the U.S. Department of Energy Office of Legacy Management (LM) traveled to the Amchitka, Alaska, Site in late August to assess the damage caused by a recent earthquake....

  11. Researchers Achieve Breakthrough in Solving Leading Cause of Gearbox Failures

    Broader source: Energy.gov [DOE]

    Accomplishing a significant milestone, researchers from the U.S. Department of Energy’s Argonne National Laboratory have successfully replicated the leading cause of wind turbine gearbox failures,...

  12. Evaluation of internal contamination levels after a radiological dispersal device incident using portal monitors

    SciTech Connect (OSTI)

    Palmer, R.C.; Hertel, Nolan; Ansari, A.; Manger, Ryan P; Freibert, E.J.

    2012-01-01

    Following a radioactive dispersal device (RDD) incident, it may be necessary to evaluate the internal contamination levels of a large number of potentially affected individuals to determine if immediate medical follow-up is necessary. Since the current laboratory capacity to screen for internal contamination is limited, rapid field screening methods can be useful in prioritizing individuals. This study evaluated the suitability of a radiation portal monitor for such screening. A model of the portal monitor was created for use with models of six anthropomorphic phantoms in Monte Carlo N-Particle Transport Code Version 5 (MCNP) X-5 Monte Carlo Team (MCNP A General Monte Carlo N-Particle Transport Code Version 5. LA-CP-03-0245. Vol. 2. Los Alamos National Laboratory, 2004.). The count rates of the portal monitor were simulated for inhalation and ingestion of likely radionuclides from an RDD for each of the phantoms. The time-dependant organ concentrations of the radionuclides were determined using Dose and Risk Calculation Software Eckerman, Leggett, Cristy, Nelson, Ryman, Sjoreen and Ward (Dose and Risk Calculation Software Ver. 8.4. ORNL/TM-2001/190. Oak Ridge National Laboratory, 2006.). Portal monitor count rates corresponding to a committed effective dose E(50) of 10 mSv are reported.

  13. The incidence of stellar mergers and mass gainers among massive stars

    SciTech Connect (OSTI)

    De Mink, S. E.; Sana, H.; Langer, N.; Izzard, R. G.; Schneider, F. R. N.

    2014-02-10

    Because the majority of massive stars are born as members of close binary systems, populations of massive main-sequence stars contain stellar mergers and products of binary mass transfer. We simulate populations of massive stars accounting for all major binary evolution effects based on the most recent binary parameter statistics and extensively evaluate the effect of model uncertainties. Assuming constant star formation, we find that 8{sub −4}{sup +9}% of a sample of early-type stars are the products of a merger resulting from a close binary system. In total we find that 30{sub −15}{sup +10}% of massive main-sequence stars are the products of binary interaction. We show that the commonly adopted approach to minimize the effects of binaries on an observed sample by excluding systems detected as binaries through radial velocity campaigns can be counterproductive. Systems with significant radial velocity variations are mostly pre-interaction systems. Excluding them substantially enhances the relative incidence of mergers and binary products in the non-radial velocity variable sample. This poses a challenge for testing single stellar evolutionary models. It also raises the question of whether certain peculiar classes of stars, such as magnetic O stars, are the result of binary interaction and it emphasizes the need to further study the effect of binarity on the diagnostics that are used to derive the fundamental properties (star-formation history, initial mass function, mass-to-light ratio) of stellar populations nearby and at high redshift.

  14. SU-E-T-208: Incidence Cancer Risk From the Radiation Treatment for Acoustic Neuroma Patient

    SciTech Connect (OSTI)

    Kim, D; Chung, W; Shin, D; Yoon, M

    2014-06-01

    Purpose: The present study aimed to compare the incidence risk of a secondary cancer from therapeutic doses in patients receiving intensitymodulated radiotherapy (IMRT), volumetric modulated arc therapy (VMAT), and stereotactic radiosurgery (SRS). Methods: Four acoustic neuroma patients were treated with IMRT, VMAT, or SRS. Their incidnece excess relative risk (ERR), excess absolute risk (EAR), and lifetime attributable risk (LAR) were estimated using the corresponding therapeutic doses measured at various organs by radio-photoluminescence glass dosimeters (RPLGD) placed inside a humanoid phantom. Results: When a prescription dose was delivered in the planning target volume of the 4 patients, the average organ equivalent doses (OED) at the thyroid, lung, normal liver, colon, bladder, prostate (or ovary), and rectum were measured. The OED decreased as the distance from the primary beam increased. The thyroid received the highest OED compared to other organs. A LAR were estimated that more than 0.03% of AN patients would get radiation-induced cancer. Conclusion: The tyroid was highest radiation-induced cancer risk after radiation treatment for AN. We found that LAR can be increased by the transmitted dose from the primary beam. No modality-specific difference in radiation-induced cancer risk was observed in our study.

  15. Cultural analysis: The missing factor in root-cause evaluation

    SciTech Connect (OSTI)

    Lamb, H.

    1989-01-01

    The purpose of this paper is to provide a model that can focus attention on appropriate cultural targets of inquiry, provide a completion criterion for root-cause completeness, and illustrate results. The illustration provided is as follows: Discover the root causes(s) related to issues of a nuclear reactor operator sleeping, inattention to duties, failure to adhere to procedures, and management inaction or adequate action.

  16. Project Profile: Evaluating the Causes of Photovoltaics Cost Reduction: Why

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    is PV different? | Department of Energy Soft Costs » Project Profile: Evaluating the Causes of Photovoltaics Cost Reduction: Why is PV different? Project Profile: Evaluating the Causes of Photovoltaics Cost Reduction: Why is PV different? Logo of Massachusetts Institute of Technology. The bar chart below the logo shows the cost reduction in photovoltaics compared to other energy-conversion technologies. PV is performing better than coal, natural gas, nuclear fusion, wind, and solar thermal

  17. New screening process for potentially cancer causing chemicals

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    New screening process for potentially cancer causing chemicals Click to share on Facebook (Opens in new window) Click to share on Twitter (Opens in new window) Click to share on Reddit (Opens in new window) Click to share on Pinterest (Opens in new window) A better way to screen chemicals that may cause cancer is under development. This image shows in two dimensions what Berkeley lab scientists are working to achieve in three dimensions: cultures containing diverse cell types (seen here using

  18. Incidence of High Nitrogen in Sintered Uranium Dioxide: A Case Study

    SciTech Connect (OSTI)

    Balakrishna, Palanki; Murty, B. Narasimha; Anuradha, M.; Yadav, R.B.; Jayaraj, R.N

    2005-05-15

    Nitrogen content, above the specified limit of 75 {mu}g(gU){sup -1}, was encountered in sintered uranium dioxide in the course of its manufacture. The cause was traced to the sintering process, wherein carbon, a degradation product of the die wall or admixed lubricant, was retained in the compact as a result of inadvertent reversal of gas flow in the sintering furnace. In the presence of carbon, the uranium dioxide reacted with nitrogen from the furnace atmosphere to form nitride. The compacts with high nitrogen were also those with low sintered density, arising from low green density. The low green density was due to filling problems of an inhomogeneous powder. The experiments carried out establish the causes of high nitrogen to be the carbon residue from lubricant when the UO{sub 2} is sintered in a cracked ammonia atmosphere.

  19. Incident report. Tube Bank C-metal wastage status report, November 1982

    SciTech Connect (OSTI)

    Not Available

    1982-11-01

    During the Hot Commissioning tests in preparation for Test Series 2, a significant degree of metal wastage occurred on the external surfaces of Tube Bank 'C'. The extent of the metal wastage was unexpected and has been a matter of concern to the Project. The report provides a history of the operational period for Tube Bank 'C' and details the measurements of metal wastage that have been recorded. The project has initiated an extensive study of the possible cause, or causes, of the metal wastage and these are discussed. Operational tests are to be carried out at Grimethorpe, CURL and CRE with a view to determining the mechanism of metal wastage that exists within the fluidized bed. The results of these tests will be reported and will form the basis for the design of a new bank, which will be installed in the combustor in due course, if required. The Project is taking necessary steps to ensure that the cause of the metal wastage is fully investigated and that the resultant slippage in the Test Series 2 schedule is minimised.

  20. Meteorological Integration for the Biological Warning and Incident Characterization (BWIC) System: General Guidance for BWIC Cities

    SciTech Connect (OSTI)

    Shaw, William J.; Wang, Weiguo; Rutz, Frederick C.; Chapman, Elaine G.; Rishel, Jeremy P.; Xie, YuLong; Seiple, Timothy E.; Allwine, K Jerry

    2007-02-16

    The U.S. Department of Homeland Security (DHS) is responsible for developing systems to detect the release of aerosolized bioagents in urban environments. The system that accomplishes this, known as BioWatch, is a robust first-generation monitoring system. In conjunction with the BioWatch detection network, DHS has also developed a software tool for cities to use to assist in their response when a bioagent is detected. This tool, the Biological Warning and Incident Characterization (BWIC) System, will eventually be deployed to all BioWatch cities to aid in the interpretation of the public health significance of indicators from the BioWatch networks. BWIC consists of a set of integrated modules, including meteorological models, that estimate the effect of a biological agent on a city’s population once it has been detected. For the meteorological models in BWIC to successfully calculate the distribution of biological material, they must have as input accurate meteorological data, and wind fields in particular. The purpose of this document is to provide guidance for cities to use in identifying sources of good-quality local meteorological data that BWIC needs to function properly. This process of finding sources of local meteorological data, evaluating the data quality and gaps in coverage, and getting the data into BWIC, referred to as meteorological integration, is described. The good news for many cities is that meteorological measurement networks are becoming increasingly common. Most of these networks allow their data to be distributed in real time via the internet. Thus, cities will often only need to evaluate the quality of available measurements and perhaps add a modest number of stations where coverage is poor.

  1. Cancer incidence among residents of the Three Mile Island accident area: 1982-1995

    SciTech Connect (OSTI)

    Han, Yueh-Ying; Youk, Ada O.; Sasser, Howell; Talbott, Evelyn O.

    2011-11-15

    Background: The Pennsylvania Department of Health established a registry of the Three Mile Island (TMI) nuclear power plant accident in 1979. Over 93% of the population present on the day of the accident within a 5-mile radius was enrolled and interviewed. We used the registry to investigate the potential cancer risk from low-dose radiation exposure among the TMI population. Methods: Cancer incidence data among the TMI cohort were available from 1982 to 1995. Because more than 97% of the population were white and few cancer cases were reported for those younger than 18 years of age, we included whites of age 18 years and older (10,446 men and 11,048 women) for further analyses. Cox regression models were used to estimate the relative risk (RR) per 0.1 m Sv and 95% confident interval (CI) of cancer by radiation-related exposures. The cancers of interest were all malignant neoplasms, cancer of bronchus, trachea, and lung, cancer of lymphatic and hematopoietic tissues, leukemia, and female breast. Results: Among men and women, there was no evidence of an increased risk for all malignant neoplasms among the TMI cohort exposed to higher maximum and likely {gamma} radiation (RR=1.00, 95% CI=0.97, 1.01 and RR=0.99, 95% CI=0.94, 1.03, respectively) after adjusting for age, gender, education, smoking, and background radiation. Elevation in risk was noted for cancer of the bronchus, trachea, and lung in relation to higher background radiation exposure (RR=1.45, 95% CI=1.02-2.05 at 8.0-8.8 {mu}R/h compared to 5.2-7.2 {mu}R/h). An increased risk of leukemia was found among men exposed to higher maximum and likely {gamma} radiation related to TMI exposure during the ten days following the accident (RR=1.15, 95% CI=1.04, 1.29 and RR=1.36, 95% CI=1.08, 1.71, respectively). This relationship was not found in women. Conclusion: Increased cancer risks from low-level radiation exposure within the TMI cohort were small and mostly statistically non-significant. However, additional

  2. Hydrogen Embrittlement of Pipeline Steels: Causes and Remediation |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Barriers: Hydrogen embrittlement of pipelines and remediation (mixing with water vapor?) hpwgw_embrittlementsteels_sofronis.pdf (675.35 KB) More Documents & Publications Webinar: I2CNER: An International Collaboration to Enable a Carbon-Neutral Energy Economy Hydrogen Embrittlement of Pipeline Steels: Causes and Remediation Hydrogen permeability and Integrity of hydrogen transfer pipelines

  3. Oblique-incidence sputtering of Ru intermediate layer for decoupling of intergranular exchange in perpendicular recording media

    SciTech Connect (OSTI)

    Saito, Shin; Inoue, Ken; Takahashi, Migaku

    2011-04-01

    During the Ru deposition process for granular type perpendicular magnetic recording media, both a reduction in the Ru intermediate layer thickness and lowering of sputtering gas pressure were successfully achieved by focusing on a self-shadowing effect. Oblique-incidence sputtering with a 60 deg. incident angle under an Ar gas pressure of 0.6 Pa yielded (1) columnar Ru grains with a growth direction of 30 deg. from the film normal, (2) c-plane sheet texture by epitaxial growth on the Pt underlayer, and (3) a flat envelope of the surface and a deep gap at grain boundaries. This change in the Ru structure significantly contributes to reducing exchange coupling among magnetic grains, especially in the initial growth region in an overlying granular medium.

  4. Grazing-incidence small-angle X-ray scattering: application to the study of quantum dot lattices

    SciTech Connect (OSTI)

    Buljan, Maja Radi?, Nikola; Bernstorff, Sigrid; Drai?, Goran; Bogdanovi?-Radovi?, Iva; Hol, Vclav

    2012-01-01

    The modelling of grazing-incidence small-angle X-ray scattering (GISAXS) from three-dimensional quantum dot lattices is described. The ordering of quantum dots in three-dimensional quantum dot lattices is investigated by grazing-incidence small-angle X-ray scattering (GISAXS). Theoretical models describing GISAXS intensity distributions for three general classes of lattices of quantum dots are proposed. The classes differ in the type of disorder of the positions of the quantum dots. The models enable full structure determination, including lattice type, lattice parameters, the type and degree of disorder in the quantum dot positions and the distributions of the quantum dot sizes. Applications of the developed models are demonstrated using experimentally measured data from several types of quantum dot lattices formed by a self-assembly process.

  5. Upgrading RESRAD-RDD and Planning for Improvised Nuclear Device Incidents--The RESRAD-RDD&IND

    Broader source: Energy.gov [DOE]

    Upgrading RESRAD-RDD and Planning for Improvised Nuclear Device Incidents--The RESRAD-RDD&IND Abstract: The RESRAD-RDD code was developed through the interagency Operational Guidelines Task Group (OGT) to assist decision makers, emergency responders, and emergency preparedness planners for response to radiological dispersal device incidents (RDD). The RESRAD-RDD code was released as a companion software tool in 2009 to support the OGT Manual—Preliminary Report on Operational Guidelines Developed for Use in Emergency Preparedness and Response to a Radiological Dispersal Device Incident (DOE/HS-0001). The original RESRAD-RDD code was Microsoft Excel based software with the user interface written in Visual Basic. This version of RESRAD-RDD is being converted to a database driven software that runs on Windows 7 operating system in the .NET environment. The new RESRAD-RDD code is being tested to make sure it reproduces old code results. The new code runs faster than the old spreadsheets code by a factor of 10 or so, fewer clicks are required for the same calculations, operational guidelines can be easily located, and the reports can be written to PDFs instead of HTML. Additional radionuclides are also being added to the new RESRAD-RDD code. An Improvised Nuclear Device (IND) scenario is also being added to the code and about 44 - 60 radionuclides will be added to handle IND incident. A new OGT Task Group is in the process of updating the OGT Manual and providing guidance on the development of the IND scenario and methodology. The new code, RESRAD-RDD&IND is expected to be released in early 2015. Charley Yu*, Argonne National Laboratory ; Carlos Corredor, U.S. Department of Energy; Jing-Jy Cheng, Argonne National Laboratory; Sunita Kamboj, Argonne National Laboratory; David LePoire, Argonne National Laboratory; Paul Flood, Argonne National Laboratory

  6. Leukemia, lymphoma and multiple myeloma mortality (19501999) and incidence (19691999) in the Eldorado uranium workers cohort

    SciTech Connect (OSTI)

    Zablotska, Lydia B.; Lane, Rachel S.D.; Frost, Stanley E.; Thompson, Patsy A.

    2014-04-01

    Uranium workers are chronically exposed to low levels of radon decay products (RDP) and gamma (?) radiation. Risks of leukemia from acute and high doses of ?-radiation are well-characterized, but risks from lower doses and dose-rates and from RDP exposures are controversial. Few studies have evaluated risks of other hematologic cancers in uranium workers. The purpose of this study was to analyze radiation-related risks of hematologic cancers in the cohort of Eldorado uranium miners and processors first employed in 19321980 in relation to cumulative RDP exposures and ?-ray doses. The average cumulative RDP exposure was 100.2 working level months and the average cumulative whole-body ?-radiation dose was 52.2 millisievert. We identified 101 deaths and 160 cases of hematologic cancers in the cohort. Overall, male workers had lower mortality and cancer incidence rates for all outcomes compared with the general Canadian male population, a likely healthy worker effect. No statistically significant association between RDP exposure or ?-ray doses, or a combination of both, and mortality or incidence of any hematologic cancer was found. We observed consistent but non-statistically significant increases in risks of chronic lymphocytic leukemia (CLL) and Hodgkin lymphoma (HL) incidence and non-Hodgkin lymphoma (NHL) mortality with increasing ?-ray doses. These findings are consistent with recent studies of increased risks of CLL and NHL incidence after ?-radiation exposure. Further research is necessary to understand risks of other hematologic cancers from low-dose exposures to ?-radiation. - Highlights: We analyzed long-term follow-up for hematologic cancers of the Eldorado uranium workers. Workers were exposed to a unique combination of radon decay products (RDP) and gamma (?) ray doses. Exposures to RDP and ?-ray doses were not associated with significantly increased risks of cancers. Radiation risks of chronic lymphocytic leukemia (CLL) and Hodgkin lymphoma were

  7. New Mexico Governor Susana Martinez and U.S Energy Secretary Ernest Moniz Announce Settlement on Nuclear Waste Incidents

    Broader source: Energy.gov [DOE]

    WASHINGTON, D.C. —Today, New Mexico Governor Susana Martinez and Secretary of Energy Ernest Moniz released the terms of a $73 million settlement of the State’s claims against the U.S. Department of Energy and its contractors related to the February 2014 incidents at the Waste Isolation Pilot Plant in Carlsbad, New Mexico, including the associated activities at the Los Alamos National Laboratory.

  8. Calculation of nuclear data for incident energies to 200 MeV with the FKK-GNASH code system

    SciTech Connect (OSTI)

    Chadwick, M.B.; Young, P.G.

    1993-02-01

    We describe how the FKK-GNASH code system has been extended to calculate nucleon-induced reactions up to 200 MeV, and used to predict (p,xn) and (p,xp) cross sections on {sup 208}Pb at incident energies of 25, 45, 80 and 160 MeV, for an intermediate energy code intercomparison. Details of the reaction mechanisms calculated by FKK-GNASH are given, and the calculational procedure is described.

  9. Causes of Mortality After Dose-Escalated Radiation Therapy and Androgen Deprivation for High-Risk Prostate Cancer

    SciTech Connect (OSTI)

    Tendulkar, Rahul D.; Hunter, Grant K.; Reddy, Chandana A.; Stephans, Kevin L.; Ciezki, Jay P.; Abdel-Wahab, May; Stephenson, Andrew J.; Klein, Eric A.; Mahadevan, Arul; Kupelian, Patrick A.

    2013-09-01

    Purpose: Men with high-risk prostate cancer have other competing causes of mortality; however, current risk stratification schema do not account for comorbidities. We aim to identify the causes of death and factors predictive for mortality in this population. Methods and Materials: A total of 660 patients with high-risk prostate cancer were treated with definitive high-dose external beam radiation therapy (?74 Gy) and androgen deprivation (AD) between 1996 and 2009 at a single institution. Cox proportional hazards regression analysis was conducted to determine factors predictive of survival. Results: The median radiation dose was 78 Gy, median duration of AD was 6 months, and median follow-up was 74 months. The 10-year overall survival (OS) was 60.6%. Prostate cancer was the leading single cause of death, with 10-year mortality of 14.1% (95% CI 10.7-17.6), compared with other cancers (8.4%, 95% CI 5.7-11.1), cardiovascular disease (7.3%, 95% CI 4.7-9.9), and all other causes (10.4%, 95% CI 7.2-13.6). On multivariate analysis, older age (HR 1.55, P=.002) and Charlson comorbidity index score (CS) ?1 (HR 2.20, P<.0001) were significant factors predictive of OS, whereas Gleason score, T stage, prostate-specific antigen, duration of AD, radiation dose, smoking history, and body mass index were not. Men younger than 70 years of age with CS = 0 were more likely to die of prostate cancer than any other cause, whereas older men or those with CS ?1 more commonly suffered non-prostate cancer death. The cumulative incidences of prostate cancer-specific mortality were similar regardless of age or comorbidities (P=.60). Conclusions: Men with high-risk prostate cancer are more likely to die of causes other than prostate cancer, except for the subgroup of men younger than 70 years of age without comorbidities. Only older age and presence of comorbidities significantly predicted for OS, whereas prostate cancer- and treatment-related factors did not.

  10. Incidence and Treatment Patterns in Hospitalizations for Malignant Spinal Cord Compression in the United States, 1998-2006

    SciTech Connect (OSTI)

    Mak, Kimberley S.; Lee, Leslie K.; Mak, Raymond H.; Wang, Shuang; Pile-Spellman, John; Abrahm, Janet L.; Prigerson, Holly G.; Balboni, Tracy A.

    2011-07-01

    Purpose: To characterize patterns in incidence, management, and costs of malignant spinal cord compression (MSCC) hospitalizations in the United States, using population-based data. Methods and Materials: Using the Nationwide Inpatient Sample, an all-payer healthcare database representative of all U.S. hospitalizations, MSCC-related hospitalizations were identified for the period 1998-2006. Cases were combined with age-adjusted Surveillance, Epidemiology and End Results cancer death data to estimate annual incidence. Linear regression characterized trends in patient, treatment, and hospital characteristics, costs, and outcomes. Logistic regression was used to examine inpatient treatment (radiotherapy [RT], surgery, or neither) by hospital characteristics and year, adjusting for confounding. Results: We identified 15,367 MSCC-related cases, representing 75,876 hospitalizations. Lung cancer (24.9%), prostate cancer (16.2%), and multiple myeloma (11.1%) were the most prevalent underlying cancer diagnoses. The annual incidence of MSCC hospitalization among patients dying of cancer was 3.4%; multiple myeloma (15.0%), Hodgkin and non-Hodgkin lymphomas (13.9%), and prostate cancer (5.5%) exhibited the highest cancer-specific incidence. Over the study period, inpatient RT for MSCC decreased (odds ratio [OR] 0.68, 95% confidence interval [CI] 0.61-0.81), whereas surgery increased (OR 1.48, 95% CI 1.17-1.84). Hospitalization costs for MSCC increased (5.3% per year, p < 0.001). Odds of inpatient RT were greater at teaching hospitals (OR 1.41, 95% CI 1.19-1.67), whereas odds of surgery were greater at urban institutions (OR 1.82, 95% CI 1.29-2.58). Conclusions: In the United States, patients dying of cancer have an estimated 3.4% annual incidence of MSCC requiring hospitalization. Inpatient management of MSCC varied over time and by hospital characteristics, with hospitalization costs increasing. Future studies are required to determine the impact of treatment patterns on MSCC

  11. The cause of outliers in electromagnetic pulse (EMP) locations

    SciTech Connect (OSTI)

    Fenimore, Edward E.

    2014-10-02

    We present methods to calculate the location of EMP pulses when observed by 5 or more satellites. Simulations show that, even with a good initial guess and fitting a location to all of the data, there are sometime outlier results whose locations are much worse than most cases. By comparing simulations using different ionospheric transfer functions (ITFs), it appears that the outliers are caused by not including the additional path length due to refraction rather than being caused by not including higher order terms in the Appleton-Hartree equation. We suggest ways that the outliers can be corrected. These correction methods require one to use an electron density profile along the line of sight from the event to the satellite rather than using the total electron content (TEC) to characterize the ionosphere.

  12. Thermal initiation caused by fragment impact on cased explosives

    SciTech Connect (OSTI)

    Schnurr, N.M. )

    1989-01-01

    Numerical calculations have been used to predict the velocity threshold for thermal initiation of a cased explosive caused by fragment impact. A structural analysis code was used to determine temperature profiles and a thermal analysis code was used to calculate reaction rates. Results generated for the United States Air Force MK 82 bomb indicate that the velocity threshold for thermal initiation is slightly higher than that for the shock-to-detonation process. 8 refs., 5 figs., 2 tabs.

  13. Caused? A Monsoon Example: India Ganges Valley Aerosol Experiment

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    issue: What is a Monsoon? How are Monsoons Caused? A Monsoon Example: India Ganges Valley Aerosol Experiment Definitions Activity About ARM: The Atmospheric Radiation Measurement (ARM) Climate Research Facility is a U.S. Department of Energy scientific user facility for the study of global climate change. As part of its outreach program, ARM provides education resources for students, teachers, and communities. www.arm.gov EDUCATION NEWS Monsoons: Bring on the Rain Imagine weeks of hot, dry heat,

  14. Hydrogen Embrittlement of Pipeline Steels: Causes and Remediation

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Embrittlement of Pipeline Steels: Causes and Remediation P. Sofronis, I. M. Robertson, D. D. Johnson University of Illinois at Urbana-Champaign Hydrogen Pipeline Working Group Workshop Augusta, GA, August 30, 2005 Funding and Duration * Timeline - Project start date: 7/20/05 - Project end date: 7/19/09 - Percent complete: 0.1% * Budget: Total project funding: 300k/yr * DOE share: 75% * Contractor share: 25% * Barriers - Hydrogen embrittlement of pipelines and remediation (mixing with water

  15. A Migrated Aortic Stent Graft Causing Erosive Spondylopathy

    SciTech Connect (OSTI)

    Gestrich, Christopher Probst, Chris; Wilhelm, Kai; Schiller, Wolfgang

    2013-12-15

    We report about a patient presenting with back pain 4 months after an uneventful endovascular implantation of an aortic stent graft. Computed tomography scan revealed a migration of the stent with consecutive endoleakage, kink formation, and movement of the stent toward the spine, which caused destruction of the aortic wall as well as vertebral necrosis. Explantation of the stent and replacement of the native aorta relieved the patient of his symptoms.

  16. New insights into microbial responses to oil spills from the Deepwater Horizon incident

    SciTech Connect (OSTI)

    Mason, O.U.; Hazen, T.C.

    2011-06-15

    On April 20, 2010, a catastrophic eruption of methane caused the Deepwater Horizon exploratory drill rig drilling the Macondo Well in Mississippi Canyon Block 252 (MC252) to explode. The Deepwater Horizon oil spill was unprecendeted for several reasons: the volume of oil released; the spill duration; the well depth; the distance from the shore-line (77 km or about 50 miles); the type of oil (light crude); and the injection of dispersant directly at the wellhead. This study clearly demonstrated that there was a profound and significant response by certain members of the in situ microbial community in the deep-sea in the Gulf of Mexico. In particular putative hydrocarbon degrading Bacteria appeared to bloom in response to the Deepwater Horizon oil spill, even though the temperature at these depths is never >5 C. As the plume aged the shifts in the microbial community on a temporal scale suggested that different, yet metabolically important members of the community were able to respond to a myriad of plume constituents, e.g. shifting from propane/ethane to alkanes and finally to methane. Thus, the biodegradation of hydrocarbons in the plume by Bacteria was a highly significant process in the natural attenuation of many compounds released during the Deepwater Horizon oil spill.

  17. Carbon monoxide inhalation increases microparticles causing vascular and CNS dysfunction

    SciTech Connect (OSTI)

    Xu, Jiajun; Yang, Ming; Kosterin, Paul; Salzberg, Brian M.; Milovanova, Tatyana N.; Bhopale, Veena M.; Thom, Stephen R.

    2013-12-01

    We hypothesized that circulating microparticles (MPs) play a role in pro-inflammatory effects associated with carbon monoxide (CO) inhalation. Mice exposed for 1 h to 100 ppm CO or more exhibit increases in circulating MPs derived from a variety of vascular cells as well as neutrophil activation. Tissue injury was quantified as 2000 kDa dextran leakage from vessels and as neutrophil sequestration in the brain and skeletal muscle; and central nervous system nerve dysfunction was documented as broadening of the neurohypophysial action potential (AP). Indices of injury occurred following exposures to 1000 ppm for 1 h or to 1000 ppm for 40 min followed by 3000 ppm for 20 min. MPs were implicated in causing injuries because infusing the surfactant MP lytic agent, polyethylene glycol telomere B (PEGtB) abrogated elevations in MPs, vascular leak, neutrophil sequestration and AP prolongation. These manifestations of tissue injury also did not occur in mice lacking myeloperoxidase. Vascular leakage and AP prolongation were produced in nave mice infused with MPs that had been obtained from CO poisoned mice, but this did not occur with MPs obtained from control mice. We conclude that CO poisoning triggers elevations of MPs that activate neutrophils which subsequently cause tissue injuries. - Highlights: Circulating microparticles (MPs) increase in mice exposed to 100 ppm CO or more. MPs are lysed by infusing the surfactant polyethylene glycol telomere B. CO-induced MPs cause neutrophil activation, vascular leak and CNS dysfunction. Similar tissue injuries do not arise with MPs obtained from air-exposed, control mice.

  18. Complementary influence functions for predicting subsidence caused by mining

    SciTech Connect (OSTI)

    Sutherland, H.J.; Munson, D.E.

    1982-01-01

    Surface subsidence caused by underground mining is described through complementary influence functions. The complementary functions developed here differ from the simple functions previously used in that the surface displacement is the result of the combined contributions of the mined and unmined zones. This eliminates computational difficulties experienced with the simple functions in determining the deflections above the rib side and in the eventual application of influence functions to complex room-and-pillar configurations. Although the analysis framework presented is intended for predicting subsidence over complex mine configurations, use of the complementary functions is illustrated adequately by application to a longwall panel of the Old Ben No. 24 coal mine.

  19. Cause not found for Texas LPG site blast

    SciTech Connect (OSTI)

    Not Available

    1992-04-20

    This paper reports that National Transportation Safety Board investigators completed the first phase of tests at Seminole Pipeline Co.'s liquid petroleum gas storage dome near Brenham, Tex., without finding the cause of an explosion there Apr. 7. But in a week of investigation, NTSB determined that a release of brine and product occurred at the 350,000 bbl LPG storage dome, about 45 miles northwest of Houston, just before the blast. The explosion sent shock waves felt as far as 130 miles away. Three persons have died from injuries suffered in the accident. Another 18 were injured.

  20. The human causes of deforestation in southeast Asia

    SciTech Connect (OSTI)

    Kummer, D.M.; Turner, B.L. II )

    1994-05-01

    The recurrent pattern of deforestation in southeast Asia is that of large scale logging for exports followed by agricultural expansion. The apparent difference between global and regional or local causes of land use, such as in SE Asia, has become a central theme in the emerging global change agenda. This article illustrates the significance of regional variation for understanding one example of land cover change, tropical deforestation, focusing on the Philippines, and using mathematical modeling. The commonalities of this case with other in SE Asia are discussed. 43 refs., 2 figs., 5 tabs.

  1. Hydrogen Embrittlement of Pipeline Steels: Causes and Remediation

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    January 2005 HYDROGEN EMBRITTLEMENT OF PIPELINE STEELS: CAUSES AND REMEDIATION P. Sofronis, I. Robertson, D. Johnson University of Illinois at Urbana-Champaign Hydrogen Pipeline R&D Project Review Meeting Oak Ridge National Laboratory, Oak Ridge TN January 5-6, 2005 2 January 2005 Hydrogen Embrittlement: Long History M.L. Cailletet (1868) in Comptes Rendus, 68, 847-850 W. H. Johnson (1875) On some remarkable changes produced in iron and steels by the action of hydrogen acids. Proc. R. Soc.

  2. Responding to Terrorist Incidents in Your Community: Flammable-Liquid Fire Fighting Techniques for Municipal and Rural Firefighters

    SciTech Connect (OSTI)

    Denise Baclawski

    2010-03-08

    The University of Nevada, Reno Fire Science Academy (FSA) applied for grant funding to develop and deliver programs for municipal, rural, and volunteer firefighters. The FSA specializes in preparing responders for a variety of emergency events, including flammable liquid fires resulting from accidents, intentional acts, or natural disasters. Live fire training on full scale burnable props is the hallmark of FSA training, allowing responders to practice critical skills in a realistic, yet safe environment. Unfortunately, flammable liquid live fire training is often not accessible to municipal, rural, or volunteer firefighters due to limited department training budgets, even though most department personnel will be exposed to flammable liquid fire incidents during the course of their careers. In response to this training need, the FSA developed a course during the first year of the grant (Year One), Responding to Terrorist Incidents in Your Community: Flammable-Liquid Fire Fighting Techniques for Municipal and Rural Firefighters. During the three years of the grant, a total of 2,029 emergency responders received this training. In Year Three, two new courses, a train-the-trainer for Responding to Terrorist Incidents in Your Community and Management of Large-Scale Disasters for Public Officials were developed and pilot tested during the Real-World Disaster Management Conference held at the FSA in June of 2007. Two research projects were conducted during Years Two and Three. The first, conducted over a two year period, evaluated student surveys regarding the value of the flammable liquids training received. The second was a needs assessment conducted for rural Nevada. Both projects provided important feedback and a basis for curricula development and improvements.

  3. Causes of Indoor Air Quality Problems in Schools: Summary of Scientific Research

    SciTech Connect (OSTI)

    Bayer, C.W.

    2001-02-22

    In the modern urban setting, most individuals spend about 80% of their time indoors and are therefore exposed to the indoor environment to a much greater extent than to the outdoors (Lebowitz 1992). Concomitant with this increased habitation in urban buildings, there have been numerous reports of adverse health effects related to indoor air quality (IAQ) (sick buildings). Most of these buildings were built in the last two decades and were constructed to be energy-efficient. The quality of air in the indoor environment can be altered by a number of factors: release of volatile compounds from furnishings, floor and wall coverings, and other finishing materials or machinery; inadequate ventilation; poor temperature and humidity control; re-entrainment of outdoor volatile organic compounds (VOCs); and the contamination of the indoor environment by microbes (particularly fungi). Armstrong Laboratory (1992) found that the three most frequent causes of IAQ are (1) inadequate design and/or maintenance of the heating, ventilation, and air-conditioning (HVAC) system, (2) a shortage of fresh air, and (3) lack of humidity control. A similar study by the National Institute for Occupational Safety and Health (NIOSH 1989) recognized inadequate ventilation as the most frequent source of IAQ problems in the work environment (52% of the time). Poor IAQ due to microbial contamination can be the result of the complex interactions of physical, chemical, and biological factors. Harmful fungal populations, once established in the HVAC system or occupied space of a modern building, may episodically produce or intensify what is known as sick building syndrome (SBS) (Cummings and Withers 1998). Indeed, SBS caused by fungi may be more enduring and recalcitrant to treatment than SBS from multiple chemical exposures (Andrae 1988). An understanding of the microbial ecology of the indoor environment is crucial to ultimately resolving many IAQ problems. The incidence of SBS related to multiple

  4. A Geographic Information Science (GISc) Approach to Characterizing Spatiotemporal Patterns of Terrorist Incidents in Iraq, 2004-2009

    SciTech Connect (OSTI)

    Medina, Richard M; Siebeneck, Laura K.; Hepner, George F.

    2011-01-01

    As terrorism on all scales continues, it is necessary to improve understanding of terrorist and insurgent activities. This article takes a Geographic Information Systems (GIS) approach to advance the understanding of spatial, social, political, and cultural triggers that influence terrorism incidents. Spatial, temporal, and spatiotemporal patterns of terrorist attacks are examined to improve knowledge about terrorist systems of training, planning, and actions. The results of this study aim to provide a foundation for understanding attack patterns and tactics in emerging havens as well as inform the creation and implementation of various counterterrorism measures.

  5. Wide-angle point-to-point x-ray imaging with almost arbitrarily large angles of incidence

    SciTech Connect (OSTI)

    Bitter, M.; Hill, K. W.; Scott, S.; Feder, R.; Ko, Jinseok; Ince-Cushman, A.; Rice, J. E.

    2008-10-15

    The paper describes a new scheme for wide-angle point-to-point x-ray imaging with almost arbitrarily large angles of incidence by a matched pair of spherically bent crystals to eliminate the astigmatism, which is a well-known imaging error of spherical mirrors. In addition to x rays, the scheme should be applicable to a very broad spectrum of the electromagnetic radiation, including microwaves, infrared and visible light, as well as UV and extreme UV radiation, if the crystals are replaced with appropriate spherical reflectors. The scheme may also be applicable to the imaging with ultrasound.

  6. Light Chain Amyloid Fibrils Cause Metabolic Dysfunction in Human Cardiomyocytes

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    McWilliams-Koeppen, Helen P.; Foster, James S.; Hackenbrack, Nicole; Ramirez-Alvarado, Marina; Donohoe, Dallas; Williams, Angela; Macy, Sallie; Wooliver, Craig; Wortham, Dale; Morrell-Falvey, Jennifer; et al

    2015-09-22

    Light chain (AL) amyloidosis is the most common form of systemic amyloid disease, and cardiomyopathy is a dire consequence, resulting in an extremely poor prognosis. AL is characterized by the production of monoclonal free light chains that deposit as amyloid fibrils principally in the heart, liver, and kidneys causing organ dysfunction. We have studied the effects of amyloid fibrils, produced from recombinant λ6 light chain variable domains, on metabolic activity of human cardiomyocytes. The data indicate that fibrils at 0.1 μM, but not monomer, significantly decrease the enzymatic activity of cellular NAD(P)H-dependent oxidoreductase, without causing significant cell death. The presencemore » of amyloid fibrils did not affect ATP levels; however, oxygen consumption was increased and reactive oxygen species were detected. Confocal fluorescence microscopy showed that fibrils bound to and remained at the cell surface with little fibril internalization. Ultimately, these data indicate that AL amyloid fibrils severely impair cardiomyocyte metabolism in a dose dependent manner. These data suggest that effective therapeutic intervention for these patients should include methods for removing potentially toxic amyloid fibrils.« less

  7. Causes of toxicity in stormwater runoff from sawmills

    SciTech Connect (OSTI)

    Bailey, H.C.; Elphick, J.R.; Potter, A.; Chao, E.; Konasewich, D.; Zak, J.B.

    1999-07-01

    Samples of stormwater runoff from nine sawmills in British Columbia, Canada, were tested for acute toxicity with juvenile rainbow trout over a 23-month period. Forty-two of the 58 samples tested exhibited toxicity. Causes of toxicity were investigated using toxicity identification evaluation techniques. Toxicity was attributed to divalent cations, particularly zinc, in 32 of the samples. The low hardness associated with most of the samples increased the potential for metal toxicity. For example, the LC50 of zinc was 14 {micro}g/L at a hardness of 5 mg/L. Toxicity in the remaining samples was largely attributed to tannins and lignins and was associated with areas of bulk log handling. No evidence was found to indicate that antisapstain chemicals applied to freshly cut wood contributed to toxicity.

  8. Redistribution of Lignin Caused by Dilute Acid Pretreatment of Biomass

    SciTech Connect (OSTI)

    Johnson, D. K.; Donohoe, B. S.; Katahira, R.; Tucker, M. P.; Vinzant, T. B.; Himmel, M. E.

    2012-01-01

    Research conducted at NREL has shown that lignin undergoes a phase transition during thermochemical pretreatments conducted above its glass transition temperature. The lignin coalesces within the plant cell wall and appears as microscopic droplets on cell surfaces. It is clear that pretreatment causes significant changes in lignin distribution in pretreatments at all scales from small laboratory reactors to pilot scale reactors. A method for selectively extracting lignin droplets from the surfaces of pretreated cell walls has allowed us to characterize the chemical nature and molecular weight distribution of this fraction. The effect of lignin redistribution on the digestibility of pretreated solids has also been tested. It is clear that removal of the droplets increases the digestibility of pretreated corn stover. The improved digestibility could be due to decreased non-specific binding of enzymes to lignin in the droplets, or because the droplets no longer block access to cellulose.

  9. Root Cause Analysis of Gastroduodenal Ulceration After Yttrium-90 Radioembolization

    SciTech Connect (OSTI)

    Lam, Marnix G. E. H.; Banerjee, Subhas; Louie, John D.; Abdelmaksoud, Mohamed H. K.; Iagaru, Andrei H.; Ennen, Rebecca E.; Sze, Daniel Y.

    2013-12-15

    IntroductionA root cause analysis was performed on the occurrence of gastroduodenal ulceration after hepatic radioembolization (RE). We aimed to identify the risk factors in the treated population and to determine the specific mechanism of nontarget RE in individual cases. Methods: The records of 247 consecutive patients treated with yttrium-90 RE for primary (n = 90) or metastatic (n = 157) liver cancer using either resin (n = 181) or glass (n = 66) microspheres were reviewed. All patients who developed a biopsy-proven microsphere-induced gastroduodenal ulcer were identified. Univariate and multivariate analyses were performed on baseline parameters and procedural data to determine possible risk factors in the total population. Individual cases were analyzed to ascertain the specific cause, including identification of the culprit vessel(s) leading to extrahepatic deposition of the microspheres. Results: Eight patients (3.2 %) developed a gastroduodenal ulcer. Stasis during injection was the strongest independent risk factor (p = 0.004), followed by distal origin of the gastroduodenal artery (p = 0.004), young age (p = 0.040), and proximal injection of the microspheres (p = 0.043). Prolonged administrations, pain during administration, whole liver treatment, and use of resin microspheres also showed interrelated trends in multivariate analysis. Retrospective review of intraprocedural and postprocedural imaging showed a probable or possible culprit vessel, each a tiny complex collateral vessel, in seven patients. Conclusion: Proximal administrations and those resulting in stasis of flow presented increased risk for gastroduodenal ulceration. Patients who had undergone bevacizumab therapy were at high risk for developing stasis.

  10. Second cancer incidence risk estimates using BEIR VII models for standard and complex external beam radiotherapy for early breast cancer

    SciTech Connect (OSTI)

    Donovan, E. M.; James, H.; Bonora, M.; Yarnold, J. R.; Evans, P. M.

    2012-10-15

    Purpose: To compare organ specific cancer incidence risks for standard and complex external beam radiotherapy (including cone beam CT verification) following breast conservation surgery for early breast cancer.Method: Doses from breast radiotherapy and kilovoltage cone beam CT (CBCT) exposures were obtained from thermoluminescent dosimeter measurements in an anthropomorphic phantom in which the positions of radiosensitive organs were delineated. Five treatment deliveries were investigated: (i) conventional tangential field whole breast radiotherapy (WBRT), (ii) noncoplanar conformal delivery applicable to accelerated partial beast irradiation (APBI), (iii) two-volume simultaneous integrated boost (SIB) treatment, (iv) forward planned three-volume SIB, and (v) inverse-planned three volume SIB. Conformal and intensity modulated radiotherapy methods were used to plan the complex treatments. Techniques spanned the range from simple methods appropriate for patient cohorts with a low cancer recurrence risk to complex plans relevant to cohorts with high recurrence risk. Delineated organs at risk included brain, salivary glands, thyroid, contralateral breast, left and right lung, esophagus, stomach, liver, colon, and bladder. Biological Effects of Ionizing Radiation (BEIR) VII cancer incidence models were applied to the measured mean organ doses to determine lifetime attributable risk (LAR) for ages at exposure from 35 to 80 yr according to radiotherapy techniques, and included dose from the CBCT imaging. Results: All LAR decreased with age at exposure and were lowest for brain, thyroid, liver, and bladder (<0.1%). There was little dependence of LAR on radiotherapy technique for these organs and for colon and stomach. LAR values for the lungs for the three SIB techniques were two to three times those from WBRT and APBI. Uncertainties in the LAR models outweigh any differences in lung LAR between the SIB methods. Constraints in the planning of the SIB methods ensured that

  11. Energetic deposition of metal ions: Observation of self-sputtering and limited sticking for off-normal angles of incidence

    SciTech Connect (OSTI)

    Wu, Hongchen; Anders, Andre

    2009-09-15

    The deposition of films under normal and off-normal angle of incidence has been investigated to show the relevance of non-sticking of and self-sputtering by energetic ions, leading to the formation of neutral atoms. The flow of energetic ions was obtained using a filtered cathodic arc system in high vacuum and therefore the ion flux had a broad energy distribution of typically 50-100 eV per ion. The range of materials included Cu, Ag, Au, Ti, and Ni. Consistent with molecular dynamics simulations published in the literature, the experiments show, for all materials, that the combined effects of non-sticking and self-sputtering are very significant, especially for large off-normal angles. Modest heating and intentional introduction of oxygen background affect the results.

  12. Geophysical variables and behavior: LIII. Epidemiological considerations for incidence of cancer and depression in areas of frequent UFO reports

    SciTech Connect (OSTI)

    Persinger, M.A.

    1988-12-01

    Luminous phenomena and anomalous physical forces have been hypothesized to be generated by focal tectonic strain fields that precede earthquakes. If these geophysical processes exist, then their spatial and temporal density should be greatest during periods of protracted, localized UFO reports; they might be used as dosimetric indicators. Contemporary epidemiological data concerning the health risks of power frequency electromagnetic fields and radon gas levels (expected correlates of certain tectonic strain fields), suggest that increased incidence (odds ratios greater 1:3) of brain tumors and leukemia should be evident within flap areas. In addition the frequency of variants of temporal lobe lability, psychological depression and posttraumatic stress should be significantly elevated. UFO field investigators, because they have repeated, intermittent close proximity to these fields, are considered to be a particularly high risk population for these disorders. 22 references.

  13. Adapting the U.S. Domestic Radiological Emergency Response Process to an Overseas Incident: FRMAC Without the F

    SciTech Connect (OSTI)

    Blumenthal, Daniel J.; Bowman, David R.; Remick, Alan

    2012-05-01

    The earthquake and resulting tsunami in Japan led to a radiological release from the Fukushima Daiichi Nuclear Power Plan, which in turn resulted in the rapid activation and deployment by the U.S. Department of Energy National Nuclear Security Administration (DOE/NNSA) emergency response teams. These teams and those from other federal agencies are typically coordinated through the Federal Radiological Monitoring and Assessment Center (FRMAC) when responding to radiological incidents in the U.S. FRMAC is the body through which the collection, analysis, and assessment of environmental radiological data are coordinated and products released to decision makers. This article discusses DOE/NNSAs role in the U.S. response to the Fukushima accident as it implemented its components of FRMAC in a foreign country, coordinated its assets, integrated with its federal partners, and collaborated with the Government of Japan. The technical details of the various data collections and analyses are covered in other articles of this issue.

  14. Realizing in-plane surface diffraction by x-ray multiple-beam diffraction with large incidence angle

    SciTech Connect (OSTI)

    Huang, Xian-Rong Gog, Thomas; Assoufid, Lahsen; Peng, Ru-Wen; Siddons, D. P.

    2014-11-03

    Based on rigorous dynamical-theory calculations, we demonstrate the principle of an x-ray multiple-beam diffraction (MBD) scheme that overcomes the long-lasting difficulties of high-resolution in-plane diffraction from crystal surfaces. This scheme only utilizes symmetric reflection geometry with large incident angles but activates the out-of-plane and in-plane diffraction processes simultaneously and separately in the continuous MBD planes. The in-plane diffraction is realized by detoured MBD, where the intermediate diffracted waves propagate parallel to the surface, which corresponds to an absolute Bragg surface diffraction configuration that is extremely sensitive to surface structures. A series of MBD diffraction and imaging techniques may be developed from this principle to study surface/interface (misfit) strains, lateral nanostructures, and phase transitions of a wide range of (pseudo)cubic crystal structures, including ultrathin epitaxial films and multilayers, quantum dots, strain-engineered semiconductor or (multi)ferroic materials, etc.

  15. Extended-range grazing-incidence spectrometer for high-resolution extreme ultraviolet measurements on an electron beam ion trap

    SciTech Connect (OSTI)

    Beiersdorfer, P.; Magee, E. W.; Brown, G. V.; Träbert, E.; Widmann, K.; Hell, N.

    2014-11-15

    A high-resolution grazing-incidence grating spectrometer has been implemented on the Livermore electron beam ion traps for performing very high-resolution measurements in the soft x-ray and extreme ultraviolet region spanning from below 10 Å to above 300 Å. The instrument operates without an entrance slit and focuses the light emitted by highly charged ions located in the roughly 50 μm wide electron beam onto a cryogenically cooled back-illuminated charge-coupled device detector. The measured line widths are below 0.025 Å above 100 Å, and the resolving power appears to be limited by the source size and Doppler broadening of the trapped ions. Comparisons with spectra obtained with existing grating spectrometers show an order of magnitude improvement in spectral resolution.

  16. Update on Common-Cause Failure Experience and Mitigation Practices

    SciTech Connect (OSTI)

    Wood, Richard Thomas; Muhlheim, Michael David; Pullum, Laura L; Smith, Cyrus M; Holcomb, David Eugene; Korsah, Kofi

    2014-04-01

    Experience in other industries has shown that digital technology can provide substantial benefits in terms of performance and reliability. However, the U.S. nuclear power industry has been slow to adopt the technology extensively in its instrumentation and control (I&C) applications because of inhibiting factors such as regulatory uncertainty, insufficient technological experience base, implementation complexity, limited availability of nuclear-qualified products and vendors, and inadequate definition of modernization cost recapture. Although there have been examples of digital technology usage in the nuclear power industry, challenges to the qualification of digital technology for high-integrity nuclear power plant (NPP) applications have severely constrained more widespread progress in achieving the benefits that are possible through the transition to digital. The U.S. Department of Energy (DOE) Office of Nuclear Energy (NE) established the Advanced Sensors and Instrumentation (ASI) technology area under the Nuclear Energy Enabling Technologies (NEET) Program to coordinate the instrumentation and controls (I&C) research across DOE NE and to identify and lead efforts to address common needs. As part of the NEET ASI research program, the Digital Technology Qualification project was established. Under this project, the Oak Ridge National Laboratory (ORNL) is leading the investigation into mitigation of digital common-cause failure (CCF) vulnerabilities for nuclear-qualified applications. This technical report documents updated and expanded findings from research activities by ORNL. Specifically, the report describes CCF experience in the nuclear and nonnuclear industries, identifies the state of the practice for CCF mitigation through key examples, and presents conclusions from the determination of knowledge gaps.

  17. Taxonomy for Common-Cause Failure Vulnerability and Mitigation

    SciTech Connect (OSTI)

    Wood, Richard Thomas; Korsah, Kofi; Mullens, James Allen; Pullum, Laura L.

    2015-09-01

    Applying current guidance and practices for common-cause failure (CCF) mitigation to digital instrumentation and control (I&C) systems has proven problematic, and the regulatory environment has been unpredictable. The potential for CCF vulnerability inhibits I&C modernization, thereby challenging the long-term sustainability of existing plants. For new plants and advanced reactor concepts, concern about CCF vulnerability in highly integrated digital I&C systems imposes a design burden that results in higher costs and increased complexity. The regulatory uncertainty in determining which mitigation strategies will be acceptable (e.g., what diversity is needed and how much is sufficient) drives designers to adopt complicated, costly solutions devised for existing plants. To address the conditions that constrain the transition to digital I&C technology by the US nuclear industry, crosscutting research is needed to resolve uncertainty, demonstrate necessary characteristics, and establish an objective basis for qualification of digital technology for nuclear power plant (NPP) I&C applications. To fulfill this research need, Oak Ridge National Laboratory is investigating mitigation of CCF vulnerability for nuclear-qualified applications. The outcome of this research is expected to contribute to a fundamentally sound, comprehensive basis to qualify digital technology for nuclear power applications. This report documents the development of a CCF taxonomy. The basis for the CCF taxonomy was generated by determining consistent terminology and establishing a classification approach. The terminology is based on definitions from standards, guides, and relevant nuclear power industry technical reports. The classification approach is derived from identified classification schemes focused on I&C systems and key characteristics, including failure modes. The CCF taxonomy provides the basis for a systematic organization of key systems aspects relevant to analyzing the potential for

  18. Incidents of Security Concern

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... IOSC program is designed, managed, and operated. This Technical Standard describes one method, commonly used throughout the U.S. Department of Energy (DOE)National Nuclear ...

  19. CANTON LAKESHORE CANTON E BEST CON NEAUT GIDD INGS EAST N ELLSWORT

    U.S. Energy Information Administration (EIA) Indexed Site

    ... WAT SON -DU HRIN G EVERGREEN KELLY HILL RED BRUSH WEILER SVILLE MEAD VI LLE LAM AR TINE ROSS LEET SDALE RPD-R ICHLAND -4 CROWS RUN WAT TSVILLE S GLADE R UN WIN ESBU RG HAT CH CORN ...

  20. OGLE-ing the Magellanic system: stellar populations in the Magellanic Bridge

    SciTech Connect (OSTI)

    Skowron, D. M.; Jacyszyn, A. M.; Udalski, A.; Szymański, M. K.; Skowron, J.; Poleski, R.; Kozłowski, S.; Kubiak, M.; Pietrzyński, G.; Soszyński, I.; Mróz, P.; Pietrukowicz, P.; Ulaczyk, K.; Wyrzykowski, Ł.

    2014-11-10

    We report the discovery of a young stellar bridge that forms a continuous connection between the Magellanic Clouds. This finding is based on number density maps for stellar populations found in data gathered by OGLE-IV that fully cover over 270 deg{sup 2} of the sky in the Magellanic Bridge area. This is the most extensive optical survey of this region to date. We find that the young population is present mainly in the western half of the MBR, which, together with the newly discovered young population in the eastern Bridge, form a continuous stream of stars connecting both galaxies along δ ∼ –73.5 deg. The young population distribution is clumped, with one of the major densities close to the SMC and the other fairly isolated and located approximately mid-way between the Clouds, which we call the OGLE island. These overdensities are well matched by H I surface density contours, although the newly found young population in the eastern Bridge is offset by ∼2 deg north from the highest H I density contour. We observe a continuity of red clump stars between the Magellanic Clouds which represent an intermediate-age population. Red clump stars are present mainly in the southern and central parts of the Magellanic Bridge, below its gaseous part, and their presence is reflected by a strong deviation from the radial density profiles of the two galaxies. This may indicate either a tidal stream of stars, or that the stellar halos of the two galaxies overlap. On the other hand, we do not observe such an overlap within an intermediate-age population represented by the top of the red giant branch and the asymptotic giant branch stars. We also see only minor mixing of the old populations of the Clouds in the southern part of the Bridge, represented by the lowest part of the red giant branch.

  1. CANTON LAKESHORE CANTON E BEST CON NEAUT GIDD INGS EAST N ELLSWORT

    U.S. Energy Information Administration (EIA) Indexed Site

    MCKEESPORT COR AOPOLIS-MOON REDHAW ST. CLAIR SC ROGGSFIELD FRANKLIN -OAK FOREST RIMERSBURG RENNERD AL E GREENVILL E PAT MOS CRABTR EE BLAC K ASH ROYALT ON N BAKERSTOWN QUEEN ROU GH RUN LUCAS BLAC K H ILL CRESTON WAT TSVILLE WADSWORTH -NORT H OAKLAN D HOM EWORT H UNIT Y ESSELBRUN ALAMED A PAR K-CROOKED RU CHERRY GROVE FRENC HTOWN ST EWART RUN MILL C REEK GLENF IELD-MOU NT NEBO HICKORY E HARRISVILLE E LEST ER GRIGGS CORNERS EN GLAN D WEST VIL LE LAKE BAILEY LAKE OAKFORD BR UNSWICK N HOR ACE

  2. CANTON LAKESHORE CANTON E BEST CON NEAUT GIDD INGS EAST N ELLSWORT

    U.S. Energy Information Administration (EIA) Indexed Site

    Gas Reserve Class No 2001 gas reserves 0.1 - 10 MMCF 10.1 - 100 MMCF 100.1 - 1,000 MMCF 1,000.1 - 10,000 MMCF 10,000.1 - 100,000 MMCF > 100,000 MMCF Appalachian Basin Boundary C a n a d a U S A OH PA MI NY Lake Erie Lake St. Claire Total Total Total Number Liquid Gas BOE of Reserves Reserves Reserves Basin Fields (Mbbl) (MMcf) (Mbbl) Appalachian 3354 79,141 9,550,156 1,670,834 2001 Proved Reserves for Entire Applachian Basin WV Appalachian Basin, OH-PA (Panel 2 of 7) Oil and Gas Fields By

  3. CANTON LAKESHORE CANTON E BEST CON NEAUT GIDD INGS EAST N ELLSWORT

    U.S. Energy Information Administration (EIA) Indexed Site

    Liquids Reserve Class No 2001 liquids reserves 0.1 - 10 Mbbl 10.1 - 100 Mbbl 100.1 - 1,000 Mbbl 1,000.1 - 10,000 Mbbl Appalachian Basin Boundary C a n a d a U S A OH PA MI NY Lake Erie Lake St. Claire Total Total Total Number Liquid Gas BOE of Reserves Reserves Reserves Basin Fields (Mbbl) (MMcf) (Mbbl) Appalachian 3354 79,141 9,550,156 1,670,834 2001 Proved Reserves for Entire Applachian Basin WV Appalachian Basin, OH-PA (Panel 2 of 7) Oil and Gas Fields By 2001 Liquids

  4. Computer systems and methods for visualizStolte; Chris ing data

    DOE Patents [OSTI]

    Stolte, Chris; Hanrahan, Patrick

    2013-01-29

    A method for forming a visual plot using a hierarchical structure of a dataset. The dataset comprises a measure and a dimension. The dimension consists of a plurality of levels. The plurality of levels form a dimension hierarchy. The visual plot is constructed based on a specification. A first level from the plurality of levels is represented by a first component of the visual plot. A second level from the plurality of levels is represented by a second component of the visual plot. The dataset is queried to retrieve data in accordance with the specification. The data includes all or a portion of the dimension and all or a portion of the measure. The visual plot is populated with the retrieved data in accordance with the specification.

  5. Protective interior wall and attach8ing means for a fusion reactor vacuum vessel

    DOE Patents [OSTI]

    Phelps, Richard D.; Upham, Gerald A.; Anderson, Paul M.

    1988-01-01

    An array of connected plates mounted on the inside wall of the vacuum vessel of a magnetic confinement reactor in order to provide a protective surface for energy deposition inside the vessel. All fasteners are concealed and protected beneath the plates, while the plates themselves share common mounting points. The entire array is installed with torqued nuts on threaded studs; provision also exists for thermal expansion by mounting each plate with two of its four mounts captured in an oversize grooved spool. A spool-washer mounting hardware allows one edge of a protective plate to be torqued while the other side remains loose, by simply inverting the spool-washer hardware.

  6. CANTON LAKESHORE CANTON E BEST CON NEAUT GIDD INGS EAST N ELLSWORT

    U.S. Energy Information Administration (EIA) Indexed Site

    (Mbbl) Appalachian 3354 79,141 9,550,156 1,670,834 2001 Proved Reserves for Entire Applachian Basin WV Appalachian Basin, OH-PA (Panel 2 of 7) Oil and Gas Fields By 2001 Liquids

  7. CANTON LAKESHORE CANTON E BEST CON NEAUT GIDD INGS EAST N ELLSWORT

    U.S. Energy Information Administration (EIA) Indexed Site

    (MMcf) (Mbbl) Appalachian 3354 79,141 9,550,156 1,670,834 2001 Proved Reserves for Entire Applachian Basin WV Appalachian Basin, OH-PA (Panel 2 of 7) Oil and Gas Fields By 2001 Gas

  8. Decision Support Tool for the Management of Debris from Radiological Dispersal Devices and Other Incidents of National Significance

    SciTech Connect (OSTI)

    Lemieux, P.; Thorneloe, S.; Hayes, C.; Rodgers, M.; Christman, R.

    2008-07-01

    Unique challenges exist for the handling, transport, and disposal of debris resulting from homeland security incidents, disasters or other national emergencies. Access to guidance to facilitate decision making to ensure the safe and timely disposal of debris is critical to helping restore a community or region and prevent further contamination or spread of disease. For a radiological dispersal device (RDD), proper characterization of the quantity, properties, and level of contamination of debris can have a significant impact on cleanup costs and timelines. A suite of decision support tools (DSTs) is being developed by the U.S. EPA's Office of Research and Development to assist individuals responsible for making decisions associated with handling, transport, and disposal of such debris. The DSTs are location-specific to help identify specific facilities and contacts for making final disposal decisions. The DSTs provide quick reference to technical information, regulations, and other information to provide decision makers with assistance in guiding disposal decisions that are important for the protection of public health, first responders, and the environment. These tools are being developed in partnership with other U.S. government agencies, EPA program offices, industry, and state and local emergency response programs. (authors)

  9. Determination of the distribution of incident solar radiation in cavity receivers with approximately real parabolic dish collectors

    SciTech Connect (OSTI)

    Bammert, K.; Lange, H. ); Hegazy, A. )

    1990-11-01

    The absorption of solar heat and the attendant thermal and mechanical loadings on the tubes of cavity receivers depend predominantly on the flux distribution of the incident solar radiation. For an axially symmetric cavity receiver with a parabolic dish collector, it is simple to determine the insolation pattern on the receiver internal surfaces if the system is ideal. In such a system the surface of the dish is perfectly parabolic (no contour flaws are present), and the sun's central ray impinges on the dish surface parallel to the focal axis (no sun tracking flaws are present). These two conditions cannot be achieved in practice, and therefore the feasible parabolic dish system is referred to as a real system although, in actual fact, it is only an approximation to any actual system. The purpose of this paper is to devise calculation principles which permit analysis of a receiver designed for ideal conditions to verify its structural adequacy under the nonideal conditions to be expected in reality. Of the many possible imperfections in real collectors, two were selected which increase the loadings sustained. The first case concerns flaws in the contour of the dish surface. These locally increase the radiation concentration on the receiver inside walls and tubing. In the second case, sun-tracking errors give rise to axially asymmetric radiation distributions. In both examples, greater than design basis loadings will occur in the receiver tubing. Both kinds of flaws considered in this paper are of a purely deterministic nature.

  10. Preliminary report on operational guidelines developed for use in emergency preparedness and response to a radiological dispersal device incident.

    SciTech Connect (OSTI)

    Yu, C.; Cheng, J.-J.; Kamboj, S.; Domotor, S.; Wallo, A.; Environmental Science Division; DOE

    2006-12-15

    This report presents preliminary operational guidelines and supporting work products developed through the interagency Operational Guidelines Task Group (OGT). The report consolidates preliminary operational guidelines, all ancillary work products, and a companion software tool that facilitates their implementation into one reference source document. The report is intended for interim use and comment and provides the foundation for fostering future reviews of the operational guidelines and their implementation within emergency preparedness and response initiatives in the event of a radiological dispersal device (RDD) incident. The report principally focuses on the technical derivation and presentation of the operational guidelines. End-user guidance providing more details on how to apply these operational guidelines within planning and response settings is being considered and developed elsewhere. The preliminary operational guidelines are categorized into seven groups on the basis of their intended application within early, intermediate, and long-term recovery phases of emergency response. We anticipate that these operational guidelines will be updated and refined by interested government agencies in response to comments and lessons learned from their review, consideration, and trial application. This review, comment, and trial application process will facilitate the selection of a final set of operational guidelines that may be more or less inclusive of the preliminary operational guidelines presented in this report. These and updated versions of the operational guidelines will be made available through the OGT public Web site (http://ogcms.energy.gov) as they become finalized for public distribution and comment.

  11. A Local Incident Flux Response Expansion Transport Method for Coupling to the Diffusion Method in Cylindrical Geometry

    SciTech Connect (OSTI)

    Dingkang Zhang; Farzad Rahnema; Abderrafi M. Ougouag

    2013-09-01

    A local incident flux response expansion transport method is developed to generate transport solutions for coupling to diffusion theory codes regardless of their solution method (e.g., fine mesh, nodal, response based, finite element, etc.) for reactor core calculations in both two-dimensional (2-D) and three-dimensional (3-D) cylindrical geometries. In this approach, a Monte Carlo method is first used to precompute the local transport solution (i.e., response function library) for each unique transport coarse node, in which diffusion theory is not valid due to strong transport effects. The response function library is then used to iteratively determine the albedo coefficients on the diffusion-transport interfaces, which are then used as the coupling parameters within the diffusion code. This interface coupling technique allows a seamless integration of the transport and diffusion methods. The new method retains the detailed heterogeneity of the transport nodes and naturally constructs any local solution within them by a simple superposition of local responses to all incoming fluxes from the contiguous coarse nodes. A new technique is also developed for coupling to fine-mesh diffusion methods/codes. The local transport method/module is tested in 2-D and 3-D pebble-bed reactor benchmark problems consisting of an inner reflector, an annular fuel region, and a controlled outer reflector. It is found that the results predicted by the transport module agree very well with the reference fluxes calculated directly by MCNP in both benchmark problems.

  12. Total Space Heat-

    Gasoline and Diesel Fuel Update (EIA)

    Commercial Buildings Energy Consumption Survey: Energy End-Use Consumption Tables Total Space Heat- ing Cool- ing Venti- lation Water Heat- ing Light- ing Cook- ing Refrig- eration...

  13. Total Space Heat-

    Gasoline and Diesel Fuel Update (EIA)

    Revised: December, 2008 Total Space Heat- ing Cool- ing Venti- lation Water Heat- ing Light- ing Cook- ing Refrig- eration Office Equip- ment Com- puters Other All Buildings...

  14. --No Title--

    Gasoline and Diesel Fuel Update (EIA)

    Intensity (thousand Btusquare foot) Total Space Heat- ing Cool- ing Venti- lation Water Heat- ing Light- ing Cook- ing Refrig- eration Office Equip- ment Com- puters Other...

  15. Total Space Heat-

    Gasoline and Diesel Fuel Update (EIA)

    Released: September, 2008 Total Space Heat- ing Cool- ing Venti- lation Water Heat- ing Light- ing Cook- ing Refrig- eration Office Equip- ment Com- puters Other All Buildings*...

  16. --No Title--

    Gasoline and Diesel Fuel Update (EIA)

    Major Fuel Consumption (trillion Btu) Total Space Heat- ing Cool- ing Venti- lation Water Heat- ing Light- ing Cook- ing Refrig- eration Office Equip- ment Com- puters Other...

  17. --No Title--

    Gasoline and Diesel Fuel Update (EIA)

    Electricity Consumption (trillion Btu) Total Space Heat- ing Cool- ing Venti- lation Water Heat- ing Light- ing Cook- ing Refrig- eration Office Equip- ment Com- puters Other...

  18. Enhanced Chemical Incident Response Plan (ECIRP). Appendix F, remediation analysis with Decision Support Tools (DSTs) for wide-area chemical hazards.

    SciTech Connect (OSTI)

    Hassig, Nancy L.; Pulsipher, Brent A.; Foltz, Greg W.; Hoette, Trisha Marie

    2011-07-01

    The Defense Threat Reduction Agency (DTRA) commissioned an assessment of the Consequence Management (CM) plans in place on military bases for response to a chemical attack. The effectiveness of the CM plans for recovering from chemical incidents was modeled using a multiple Decision Support Tools (DSTs). First, a scenario was developed based on an aerial dispersion of a chemical agent over a wide-area of land. The extent of contamination was modeled with the Hazard Prediction and Assessment Capability (HPAC) tool. Subsequently, the Analyzer for Wide Area Restoration Effectiveness (AWARE) tool was used to estimate the cost and time demands for remediation based on input of contamination maps, sampling and decontamination resources, strategies, rates and costs. The sampling strategies incorporated in the calculation were designed using the Visual Sample Plan (VSP) tool. Based on a gaps assessment and the DST remediation analysis, an Enhanced Chemical Incident Response Plan (ECIRP) was developed.

  19. New opportunities for quasielastic and inelastic neutron scattering at steady-state sources using mechanical selection of the incident and final neutron energy

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Mamantov, Eugene

    2015-06-12

    We propose a modification of the neutron wide-angle velocity selector (WAVES) device that enables inelastic (in particular, quasielastic) scattering measurements not relying on the neutron time-of-flight. The proposed device is highly suitable for a steady-state neutron source, somewhat similar to a triple-axis spectrometer, but with simultaneous selection of the incident and final neutron energy over a broad range of scattering momentum transfer. Both the incident and final neutron velocities are defined by the WAVES geometry and rotation frequency. The variable energy transfer is achieved through the natural variation of the velocity of the transmitted neutrons as a function of themore » scattering angle component out of the equatorial plane.« less

  20. On the cause of conductivity degradation in sodium strontium silicate ionic conductor

    SciTech Connect (OSTI)

    Jee, Y; Zhao, X; Huang, K

    2015-01-01

    Here we present strong experimental evidence that elucidates the fundamental cause for the conductivity degradation observed in Na-SrSiO3 ionic conductor.

  1. V-204: A specially crafted query can cause BIND to terminate...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    affected source distributions may crash with assertion failures triggered in the same fashion. IMPACT: A specially crafted DNS query could cause the DNS service to terminate...

  2. An estimate of the error caused by the elongation of the wavelength in a focused beam in free-space electromagnetic parameters measurement

    SciTech Connect (OSTI)

    Zhang, Yunpeng; Li, En Guo, Gaofeng; Xu, Jiadi; Wang, Chao

    2014-09-15

    A pair of spot-focusing horn lens antenna is the key component in a free-space measurement system. The electromagnetic constitutive parameters of a planar sample are determined using transmitted and reflected electromagnetic beams. These parameters are obtained from the measured scattering parameters by the microwave network analyzer, thickness of the sample, and wavelength of a focused beam on the sample. Free-space techniques introduced by most papers consider the focused wavelength as the free-space wavelength. But in fact, the incident wave projected by a lens into the sample approximates a Gaussian beam, thus, there has an elongation of the wavelength in the focused beam and this elongation should be taken into consideration in dielectric and magnetic measurement. In this paper, elongation of the wavelength has been analyzed and measured. Measurement results show that the focused wavelength in the vicinity of the focus has an elongation of 1%5% relative to the free-space wavelength. Elongation's influence on the measurement result of the permittivity and permeability has been investigated. Numerical analyses show that the elongation of the focused wavelength can cause the increase of the measured value of the permeability relative to traditionally measured value, but for the permittivity, it is affected by several parameters and may increase or decrease relative to traditionally measured value.

  3. EVMS Training Snippet: 1.6 DOE EVMS Review for Cause | Department of Energy

    Office of Environmental Management (EM)

    6 DOE EVMS Review for Cause EVMS Training Snippet: 1.6 DOE EVMS Review for Cause This EVMS Training Snippet, sponsored by the Office of Project Management (PM), covers the DOE Earned Value Management Systems Review for Cause process. Link to Video Presentation (12:24) | Prior Snippet (1.5) | Next Snippet (1.7) | Return to Index Slides Only (321.43 KB) Slides with Notes (1.1 MB) Key Resources PMCDP EVMS PARS IIe FPD Resource Center PM Newsletter Forms and Templates More Documents &

  4. eFRMAC Overview: Data Management and Enabling Technologies for Characterization of a Radiological Release A Case Study: The Fukushima Nuclear Power Plant Incident

    SciTech Connect (OSTI)

    Blumenthal, Daniel J.; Clark, Harvey W.; Essex, James J.; Wagner, Eric C.

    2013-07-01

    The eFRMAC enterprise is a suite of technologies and software developed by the United States Department of Energy, National Nuclear Security Administration’s Office of Emergency Response to coordinate the rapid data collection, management, and analysis required during a radiological emergency. This enables the Federal Radiological Monitoring and Assessment Center assets to evaluate a radiological or nuclear incident efficiently to facilitate protective actions to protect public health and the environment. This document identifies and describes eFRMAC methods including (1) data acquisition, (2) data management, (3) data analysis, (4) product creation, (5) quality control, and (6) dissemination.

  5. B&W Y-12 responds to NNSA's show cause letter | Y-12 National...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    responds to ... B&W Y-12 responds to NNSA's show cause letter Posted: September 12, 2012 - 3:29pm On September 10, B&W Y-12 provided its response to the National Nuclear Security ...

  6. FIA-12-0050- In the Matter of Cause of Action

    Broader source: Energy.gov [DOE]

    On October 4, 2012, The Office of Hearings and Appeals (OHA) granted an Appeal filed by Cause of Action (COA) under the FOIA of a final determination issued by the Loan Guarantee Program Office ...

  7. FIA-13-0015 - In the Matter of Cause of Action | Department of...

    Broader source: Energy.gov (indexed) [DOE]

    part a Freedom of Information Act (FOIA) Appeal filed by the Cause of Action (Appellant) ... However, LGPO did locate information responsive to the request after the Appeal was filed. ...

  8. Measurement of the orbit fluctuation caused by an insertion device with the amplitude modulation method

    SciTech Connect (OSTI)

    Nakatani, T.; Agui, A.; Yoshigoe, A.; Matsushita, T.; Takao, M.; Aoyagi, H.; Takeuchi, M.; Tanaka, H.

    2004-05-12

    We have developed a new method to extract only the orbit fluctuation caused by changing magnetic field error of an insertion device (ID). This method consists of two main parts. (i) The orbit fluctuation is measured with modulating the error field of the ID by using the real-time beam position measuring system. (ii) The orbit fluctuation depending on the variation of the error field of the ID is extracted by the filter applying the Wavelet Transform. We call this approach the amplitude modulation method. This analysis technique was applied to measure the orbit fluctuation caused by the error field of APPLE-2 type undulator (ID23) installed in the SPring-8 storage ring. We quantitatively measured two kinds of the orbit fluctuation which are the static term caused by the magnetic field error and the dynamic term caused by the eddy current on the ID23 chamber.

  9. Root Cause Analysis Report In Response to Condition Report 5223 Regarding

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Emails Suggesting Noncompliance with Quality Assurance Requirements | Department of Energy Root Cause Analysis Report In Response to Condition Report 5223 Regarding Emails Suggesting Noncompliance with Quality Assurance Requirements Root Cause Analysis Report In Response to Condition Report 5223 Regarding Emails Suggesting Noncompliance with Quality Assurance Requirements U.S. Department of Energy Office of Civilian Radioactive Waste Management 1 (9.48 MB) More Documents & Publications

  10. Statistics Show Bearing Problems Cause the Majority of Wind Turbine Gearbox

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Failures | Department of Energy Statistics Show Bearing Problems Cause the Majority of Wind Turbine Gearbox Failures Statistics Show Bearing Problems Cause the Majority of Wind Turbine Gearbox Failures September 17, 2015 - 12:29pm Addthis In the past, the wind energy industry has been relatively conservative in terms of data sharing, especially with the general public, which has inhibited the research community's efforts to identify and mitigate the premature failures of wind turbine

  11. The Influence of Radiation in Altering the Incidence of Mutations in Drosophila. Progress Report on the Past Twelve Months and Renewal Proposal for the Period September 15, 1960 to September 14, 1961

    DOE R&D Accomplishments [OSTI]

    Muller, H. J.

    1960-05-31

    Progress is reported in studies on the effects of radiation on the incidence of mutations in Drosophila. Results are summarized and the findings are interpreted. A list is included of papers published during the period. (C.H.)

  12. Scheme for precise correction of orbit variation caused by dipole error field of insertion device

    SciTech Connect (OSTI)

    Nakatani, T.; Agui, A.; Aoyagi, H.; Matsushita, T.; Takao, M.; Takeuchi, M.; Yoshigoe, A.; Tanaka, H.

    2005-05-15

    We developed a scheme for precisely correcting the orbit variation caused by a dipole error field of an insertion device (ID) in a storage ring and investigated its performance. The key point for achieving the precise correction is to extract the variation of the beam orbit caused by the change of the ID error field from the observed variation. We periodically change parameters such as the gap and phase of the specified ID with a mirror-symmetric pattern over the measurement period to modulate the variation. The orbit variation is measured using conventional wide-frequency-band detectors and then the induced variation is extracted precisely through averaging and filtering procedures. Furthermore, the mirror-symmetric pattern enables us to independently extract the orbit variations caused by a static error field and by a dynamic one, e.g., an error field induced by the dynamical change of the ID gap or phase parameter. We built a time synchronization measurement system with a sampling rate of 100 Hz and applied the scheme to the correction of the orbit variation caused by the error field of an APPLE-2-type undulator installed in the SPring-8 storage ring. The result shows that the developed scheme markedly improves the correction performance and suppresses the orbit variation caused by the ID error field down to the order of submicron. This scheme is applicable not only to the correction of the orbit variation caused by a special ID, the gap or phase of which is periodically changed during an experiment, but also to the correction of the orbit variation caused by a conventional ID which is used with a fixed gap and phase.

  13. Scientists say climate change could cause a 'massive' tree die-off in

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    the U.S. Southwest Climate change could cause a 'massive' tree die-off in the U.S. Southwest Scientists say climate change could cause a 'massive' tree die-off in the U.S. Southwest In a troubling new study says a warming climate could trigger a "massive" dieoff of coniferous trees in the U.S. southwest sometime this century. December 24, 2015 Dying conifers, particularly ponderosa pine (Pinus ponderosa) and sugar pine (Pinus lambertiana) in California's Sequoia National Park,

  14. Analysis of cause and mechanism for injection-induced seismicityat the Geysers Geothermal Field, California

    SciTech Connect (OSTI)

    Rutqvist, Jonny; Oldenburg, Curtis

    2007-06-14

    We analyzed relative contributions to the cause andmechanism of injection-induced seismicity at The Geysers geothermalfield, California, using coupled thermal-hydrological-mechanicalmodeling. Our analysis shows that the most important cause forinjection-induced seismicity is injection-induced cooling and associatedthermal-elastic shrinkage that changes the stress state in such a waythat mechanical failure and seismicity can be induced. Specifically, thecooling shrinkage results in unloading and associated loss of shearstrength in critically shear-stressed fractures, which are thenreactivated. Thus, our analysis shows that cooling-induced shear slipalong fractures is the dominant mechanism of injection-induced seismicityat The Geysers.

  15. [FIXED] perl 5.16.0 File::Glob() causes crashes

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    perl 5.16.0 File::Glob() causes crashes [FIXED] perl 5.16.0 File::Glob() causes crashes August 15, 2013 by Doug Jacobsen There is an issue with the default modules installation of perl where the glob() function can crash the perl executable. This happens if multiple (space separated) patterns are being matched by glob(): OK: my @files = glob("*.pl"); NOT OK: my @files = glob("*.pl *.c"); Note that the above case is so simple it usually works, more complex cases fail. This is

  16. Synthetic peptides that cause F-actin bundling and block actin depolymerization

    DOE Patents [OSTI]

    Sederoff, Heike; Huber, Steven C; Larabell, Carolyn A

    2011-10-18

    Synthetic peptides derived from sucrose synthase, and having homology to actin and actin-related proteins, sharing a common motif, useful for causing acting bundling and preventing actin depolymerization. Peptides exhibiting the common motif are described, as well as specific synthetic peptides which caused bundled actin and inhibit actin depolymerization. These peptides can be useful for treating a subject suffering from a disease characterized by cells having neoplastic growth, for anti-cancer therapeutics, delivered to subjects solely, or concomitantly or sequentially with other known cancer therapeutics. These peptides can also be used for stabilizing microfilaments in living cells and inhibiting growth of cells.

  17. Differential cross section of γn→K+Σ- on bound neutrons with incident photons from 1.1 to 3.6 GeV

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Pereira, S. Anefalos; Mirazita, M.; Rossi, P.; De Sanctis, E.; Niculescu, G.; Niculescu, I.; Stepanyan, S.; Adhikari, K. P.; Aghasyan, M.; Anghinolfi, M.; et al

    2010-05-01

    Differential cross sections of the reaction γd → K+Σ–(p) have been measured with the CLAS detector at Jefferson Lab using incident photons with energies between 1.1 and 3.6 GeV. This is the first complete set of strangeness photoproduction data on the neutron covering a broad angular range. At energies close to threshold and up to Eγ ~ 1.8 GeV, the shape of the angular distribution is suggestive of the presence of s -channel production mechanisms. For Eγ > 1.8 GeV, a clear forward peak appears and becomes more prominent as the photon energy increases, suggesting contributions from t-channel production mechanisms.more » Furthermore, these data can be used to constrain future analysis of this reaction.« less

  18. Discrimination and quantification of contamination and implanted solar wind in Genesis collector shards using grazing incidence synchrotron x-ray techniqies: Initial results

    SciTech Connect (OSTI)

    Kitts, K.; Sutton, S.; Eng, P.; Ghose, S.; Burnett, D.

    2006-12-13

    Grazing incidence X-ray fluorescence is a non-destructive technique that can differentiate the embedded solar wind component from surface contamination and collector background in the Genesis shards. Initial solar Fe abundance in D30554 is 8 x 10{sup 12}/cm{sup 2}. Accurate knowledge of the composition of the Sun provides a baseline, which allows an understanding of how the solar system has evolved over time and how solar processes and solar wind mechanics behave. Unfortunately, the errors in photospheric abundances are too large for many planetary science problems and this hampers our understanding of these different processes. Analyses of solar wind implanted in meteorites or lunar soils have provided more precise data but alteration processes on these bodies may complicate such information. In response to this need for pristine solar wind samples, NASA developed and launched the Genesis Probe. Unfortunately, the probe smashed into the Utah desert shattering the 300 collector plates into 15,000+ pieces all of which are now coated in a both a fine terrestrial dust and Si and Ge powder from the disrupted collectors themselves. The solar wind penetration depth is 100-200 nm and the superposed contamination layers are typically 40-50 nm. Stringent cleaning regimes have the potential of removing the solar wind itself. The best solution is to have sufficient spatial resolution to separately analyze the surface contamination and penetrated solar wind. To that end, three Genesis collector array shards and their appropriate flight spares were characterized via grazing incidence x-ray fluorescence and x-ray reflectivity. The goals were (1) to evaluate the various cleaning methods used to eliminate contamination, (2) to identify the collector substrates most suited for this technique, (3) to determine whether the solar wind signature could be deconvolved from the collector background signature, and (4) to measure the relative abundances of Ca to Ge in the embedded solar

  19. Energy dependence of fission product yields from 235U, 238U and 239Pu for incident neutron energies between 0.5 and 14.8 MeV

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Gooden, M. E.; Arnold, C. W.; Becker, J. A.; Bhatia, C.; Bhike, M.; Bond, E. M.; Bredeweg, T. A.; Fallin, B.; Fowler, M. M.; Howell, C. R.; et al

    2016-01-06

    In this study, Fission Product Yields (FPY) have historically been one of the most observable features of the fission process. They are known to have strong variations that are dependent on the fissioning species, the excitation energy, and the angular momentum of the compound system. However, consistent and systematic studies of the variation of these FPY with energy have proved challenging. This is caused primarily by the nature of the experiments that have traditionally relied on radiochemical procedures to isolate specific fission products. Although radiochemical procedures exist that can isolate all products, each element presents specific challenges and introduces varyingmore » degrees of systematic errors that can make inter-comparison of FPY uncertain. Although of high importance in fields such as nuclear forensics and Stockpile Stewardship, accurate information about the energy dependence of neutron induced FPY are sparse, due primarily to the lack of suitable monoenergetic neutron sources. There is a clear need for improved data, and to address this issue, a collaboration was formed between Los Alamos National Laboratory (LANL), Lawrence Livermore National Laboratory (LLNL) and the Triangle Universities Nuclear Laboratory (TUNL) to measure the energy dependence of FPY for 235U, 238U and 239Pu. The measurements have been performed at TUNL, using a 10 MV Tandem Van de Graaff accelerator to produce monoenergetic neutrons at energies between 0.6 MeV to 14.8 MeV through a variety of reactions. The measurements have utilized a dual-fission chamber, with thin (10-100 μg/cm2) reference foils of similar material to a thick (100-400 mg) activation target held in the center between the chambers. This method allows for the accurate determination of the number of fissions that occurred in the thick target without requiring knowledge of the fission cross section or neutron fluence on target. Following activation, the thick target was removed from the dual

  20. Hanford Single-Shell Tank Leak Causes and Locations - 241-B Farm

    SciTech Connect (OSTI)

    Girardot, Crystal L.; Harlow, Donald G.

    2013-07-11

    This document identifies 241-B Tank Farm (B Farm) leak cause and locations for the 100 series leaking tank (241-B-107) identified in RPP-RPT-49089, Hanford B-Farm Leak Inventory Assessments Report. This document satisfies the B Farm portion of the target (T04) in the Hanford Federal Facility Agreement and Consent Order milestone M-045-91F.

  1. Atmospheric changes caused by galactic cosmic rays over the period 1960–2010

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Jackman, Charles H.; Marsh, Daniel R.; Kinnison, Douglas E.; Mertens, Christopher J.; Fleming, Eric L.

    2016-05-13

    The Specified Dynamics version of the Whole Atmosphere Community Climate Model (SD-WACCM) and the Goddard Space Flight Center two-dimensional (GSFC 2-D) models are used to investigate the effect of galactic cosmic rays (GCRs) on the atmosphere over the 1960–2010 time period. The Nowcast of Atmospheric Ionizing Radiation for Aviation Safety (NAIRAS) computation of the GCR-caused ionization rates are used in these simulations. GCR-caused maximum NOx increases of 4–15 % are computed in the Southern polar troposphere with associated ozone increases of 1–2 %. NOx increases of ~1–6 % are calculated for the lower stratosphere with associated ozone decreases of 0.2–1more » %. The primary impact of GCRs on ozone was due to their production of NOx. The impact of GCRs varies with the atmospheric chlorine loading, sulfate aerosol loading, and solar cycle variation. Because of the interference between the NOx and ClOx ozone loss cycles (e.g., the ClO + NO2+ M → ClONO2+ M reaction) and the change in the importance of ClOx in the ozone budget, GCRs cause larger atmospheric impacts with less chlorine loading. GCRs also cause larger atmospheric impacts with less sulfate aerosol loading and for years closer to solar minimum. GCR-caused decreases of annual average global total ozone (AAGTO) were computed to be 0.2 % or less with GCR-caused column ozone increases between 1000 and 100 hPa of 0.08 % or less and GCR-caused column ozone decreases between 100 and 1 hPa of 0.23 % or less. Although these computed ozone impacts are small, GCRs provide a natural influence on ozone and need to be quantified over long time periods. This result serves as a lower limit because of the use of the ionization model NAIRAS/HZETRN which underestimates the ion production by neglecting electromagnetic and muon branches of the cosmic ray induced cascade. Furthermore, this will be corrected in future works.« less

  2. Post-Closure Inspection Letter Report for Corrective Action Units (CAUs) on the Nevada National Security Site (NNSS)

    SciTech Connect (OSTI)

    NSTec Environmental Restoration

    2012-05-16

    This letter serves as the post-closure inspection letter report for CAUs on the NNSS for Calendar Year 2011

  3. Common-Cause Failure Treatment in Event Assessment: Basis for a Proposed New Model

    SciTech Connect (OSTI)

    Dana Kelly; Song-Hua Shen; Gary DeMoss; Kevin Coyne; Don Marksberry

    2010-06-01

    Event assessment is an application of probabilistic risk assessment in which observed equipment failures and outages are mapped into the risk model to obtain a numerical estimate of the events risk significance. In this paper, we focus on retrospective assessments to estimate the risk significance of degraded conditions such as equipment failure accompanied by a deficiency in a process such as maintenance practices. In modeling such events, the basic events in the risk model that are associated with observed failures and other off-normal situations are typically configured to be failed, while those associated with observed successes and unchallenged components are assumed capable of failing, typically with their baseline probabilities. This is referred to as the failure memory approach to event assessment. The conditioning of common-cause failure probabilities for the common cause component group associated with the observed component failure is particularly important, as it is insufficient to simply leave these probabilities at their baseline values, and doing so may result in a significant underestimate of risk significance for the event. Past work in this area has focused on the mathematics of the adjustment. In this paper, we review the Basic Parameter Model for common-cause failure, which underlies most current risk modelling, discuss the limitations of this model with respect to event assessment, and introduce a proposed new framework for common-cause failure, which uses a Bayesian network to model underlying causes of failure, and which has the potential to overcome the limitations of the Basic Parameter Model with respect to event assessment.

  4. OTEC cold water pipe design for problems caused by vortex-excited oscillations

    SciTech Connect (OSTI)

    Griffin, O. M.

    1980-03-14

    Vortex-excited oscillations of marine structures result in reduced fatigue life, large hydrodynamic forces and induced stresses, and sometimes lead to structural damage and to diestructive failures. The cold water pipe of an OTEC plant is nominally a bluff, flexible cylinder with a large aspect ratio (L/D = length/diameter), and is likely to be susceptible to resonant vortex-excited oscillations. The objective of this report is to survey recent results pertaining to the vortex-excited oscillations of structures in general and to consider the application of these findings to the design of the OTEC cold water pipe. Practical design calculations are given as examples throughout the various sections of the report. This report is limited in scope to the problems of vortex shedding from bluff, flexible structures in steady currents and the resulting vortex-excited oscillations. The effects of flow non-uniformities, surface roughness of the cylinder, and inclination to the incident flow are considered in addition to the case of a smooth cyliner in a uniform stream. Emphasis is placed upon design procedures, hydrodynamic coefficients applicable in practice, and the specification of structural response parameters relevant to the OTEC cold water pipe. There are important problems associated with in shedding of vortices from cylinders in waves and from the combined action of waves and currents, but these complex fluid/structure interactions are not considered in this report.

  5. Analysis of Pressurized Water Reactor Primary Coolant Leak Events Caused by Thermal Fatigue

    SciTech Connect (OSTI)

    C. L. Atwood; V. N. Shah; W. J. Galyean

    1999-09-01

    We present statistical analyses of pressurized water reactor (PWR) primary coolant leak events caused by thermal fatigue, and discuss their safety significance. Our worldwide data contain 13 leak events (through-wall cracking) in 3509 reactor-years, all in stainless steel piping with diameter less than 25 cm. Several types of data analysis show that the frequency of leak events (events per reactor-year) is increasing with plant age, and the increase is statistically significant. When an exponential trend model is assumed, the leak frequency is estimated to double every 8 years of reactor age, although this result should not be extrapolated to plants much older than 25 years. Difficulties in arresting this increase include lack of quantitative understanding of the phenomena causing thermal fatigue, lack of understanding of crack growth, and difficulty in detecting existing cracks.

  6. Geomechanical Modeling to Investigate the Cause of Oil Leaks in Wellbores

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    at Big Hill Strategic Petroleum Reserve Geomechanical Modeling to Investigate the Cause of Oil Leaks in Wellbores at Big Hill Strategic Petroleum Reserve - Sandia Energy Energy Search Icon Sandia Home Locations Contact Us Employee Locator Energy & Climate Secure & Sustainable Energy Future Stationary Power Energy Conversion Efficiency Solar Energy Wind Energy Water Power Supercritical CO2 Geothermal Natural Gas Safety, Security & Resilience of the Energy Infrastructure Energy

  7. Bleeding peptic ulcer caused by ectopic gastric mucosa in a duplicated segment of jejunum

    SciTech Connect (OSTI)

    Newmark, H.; Ching, G.; Halls, J.; Levy, I.J.

    1981-02-01

    The authors present a case in which a patient suffered a bleeding jejunal ulcer caused by heterotopic gastric mucosa in a congenital duplication of a segment of jejunum. This is the first case diagnosed preoperatively by two different radiographic means. These lesions were shown by both pertechnetate flow and barium small bowel studies. The rarity of these entities and the modalities used for diagnosis are described.

  8. Hanford Single-Shell Tank Leak Causes and Locations - 241-C Farm

    SciTech Connect (OSTI)

    Girardot, Crystal L.; Harlow, Donald G.

    2013-07-30

    This document identifies 241-C Tank Farm (C Farm) leak causes and locations for the 100 series leaking tanks (241-C-101 and 241-C-105) identified in RPP-RPT-33418, Rev. 2, Hanford C-Farm Leak Inventory Assessments Report. This document satisfies the C Farm portion of the target (T04) in the Hanford Federal Facility Agreement and Consent Order milestone M-045-91F.

  9. Hanford Single Shell Tank Leak Causes and Locations - 241-TX Farm

    SciTech Connect (OSTI)

    Girardot, C. L.; Harlow, D> G.

    2014-07-22

    This document identifies 241-TX Tank Farm (TX Farm) leak causes and locations for the 100 series leaking tanks (241-TX-107 and 241-TX-114) identified in RPP-RPT-50870, Rev. 0, Hanford 241-TX Farm Leak Inventory Assessment Report. This document satisfies the TX Farm portion of the target (T04) in the Hanford Federal Facility Agreement and Consent Order milestone M-045-91F.

  10. Hanford Single-Shell Tank Leak Causes and Locations - 241-T Farm

    SciTech Connect (OSTI)

    Girardot, Crystal L.; Harlow, Donald G.

    2014-05-15

    This document identifies 241-T Tank Farm (T Farm) leak causes and locations for the 100 series leaking tanks (241-T-106 and 241-T-111) identified in RPP-RPT-55084, Rev. 0, Hanford 241-T Farm Leak Inventory Assessment Report. This document satisfies the T Farm portion of the target (T04) in the Hanford Federal Facility Agreement and Consent Order milestone M-045-91F.

  11. Hanford Single-Shell Tank Leak Causes and Locations - 241-U Farm

    SciTech Connect (OSTI)

    Girardot, Crystal L.; Harlow, Donald G.

    2013-12-02

    This document identifies 241-U Tank Farm (U Farm) leak causes and locations for the 100 series leaking tanks (241-U-104, 241-U-110, and 241-U-112) identified in RPP-RPT-50097, Rev. 0, Hanford 241-U Farm Leak Inventory Assessment Report. This document satisfies the U-Farm portion of the target (T04) in the Hanford Federal Facility Agreement and Consent Order milestone M-045-91F.

  12. Hanford Single-Shell Tank Leak Causes and Locations - 241-A Farm

    SciTech Connect (OSTI)

    Girardot, Crystal L.; Harlow, Donald G.

    2013-09-10

    This document identifies 241-A Tank Farm (A Farm) leak causes and locations for the 100 series leaking tanks (241-A-104 and 241-A-105) identified in RPP-ENV-37956, Hanford A and AX Farm Leak Assessment Report. This document satisfies the A Farm portion of the target (T04) in the Hanford Federal Facility Agreement and Consent Order milestone M-045-91F.

  13. Identification of the cause of weak acute toxicity to rainbow trout at a petroleum refinery

    SciTech Connect (OSTI)

    Arnold, W.R.; Zaleski, R.T.; Biddinger, G.R.

    1995-12-31

    The refinery in question performs flow through acute toxicity tests on its effluent four times per month using three fish species: fathead minnows (Pimephales promelas), threespine sticklebacks (Gasterosteus oculeatus) and rainbow trout (Oncorhynchus mykiss). Several months of monitoring data indicated a transient low level acute toxicity to rainbow trout. In most cases, several days were required for mortality to occur in the flow through tests and numerous attempts to reproduce toxicity in static and static renewal tests were unsuccessful. A decision was made to manipulate the effluent in an attempt to enhance the toxic effect in the static mode so that conventional methods could be used to identify the cause. these tests indicated that toxicity was pH dependent. Additional testing, using EPA`s Phase 1 Toxicity Identification Evaluation methods suggested that the cause of toxicity was probably an organic acid. Experiments were subsequently begun to identify the specific cause and source of toxicity. This paper reviews the problems confronted during the various phases of the study and the decisions that were made that eventually led to an understanding of the basis of toxicity.

  14. LANL responds to radiological incident

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Center(LANSCE). Aerial view of the Los Alamos Neutron Science Center (LANSCE). The contamination poses no danger to the public. The Laboratory is investigating the inadvertent...

  15. Hazardous Materials Incident Response Procedure

    Broader source: Energy.gov [DOE]

    The purpose of this procedure is to provide guidance for developing an emergency response plan, as outlined in OSHA’s 29 CFR 1910.120(q), for facility response.  This model has been adopted and...

  16. Base changes in tumour DNA have the power to reveal the causes and evolution of cancer

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Hollstein, M.; Alexandrov, L. B.; Wild, C. P.; Ardin, M.; Zavadil, J.

    2016-06-06

    Next-generation sequencing (NGS) technology has demonstrated that the cancer genomes are peppered with mutations. Although most somatic tumour mutations are unlikely to have any role in the cancer process per se, the spectra of DNA sequence changes in tumour mutation catalogues have the potential to identify the mutagens, and to reveal the mutagenic processes responsible for human cancer. Very recently, a novel approach for data mining of the vast compilations of tumour NGS data succeeded in separating and precisely defining at least 30 distinct patterns of sequence change hidden in mutation databases. At least half of these mutational signatures canmore » be readily assigned to known human carcinogenic exposures or endogenous mechanisms of mutagenesis. A quantum leap in our knowledge of mutagenesis in human cancers has resulted, stimulating a flurry of research activity. We trace here the major findings leading first to the hypothesis that carcinogenic insults leave characteristic imprints on the DNA sequence of tumours, and culminating in empirical evidence from NGS data that well-defined carcinogen mutational signatures are indeed present in tumour genomic DNA from a variety of cancer types. The notion that tumour DNAs can divulge environmental sources of mutation is now a well-accepted fact. This approach to cancer aetiology has also incriminated various endogenous, enzyme-driven processes that increase the somatic mutation load in sporadic cancers. The tasks now confronting the field of molecular epidemiology are to assign mutagenic processes to orphan and newly discovered tumour mutation patterns, and to determine whether avoidable cancer risk factors influence signatures produced by endogenous enzymatic mechanisms. As a result, innovative research with experimental models and exploitation of the geographical heterogeneity in cancer incidence can address these challenges.« less

  17. Can we treat CO₂ well blowouts like routine plumbing problems? A study of the incidence, impact, and perception of loss of well control

    SciTech Connect (OSTI)

    Porse, Sean L.; Wade, Sarah; Hovorka, Susan D.

    2014-12-31

    Risk communication literature suggests that for a number of reasons, the public may perceive a risk to be greater than indicated by its statistical probability. Public concern over risk can lead to significant and costly delays in project permitting and operations. Considering these theories, media coverage of CO₂-related well blowouts in 2013 gave rise to the questions: What is the risk of CO₂ well blowouts associated with CCUS through CO₂ EOR? What is the potential public perception of those risks? What information could be used to respond to public concern? To address these questions, this study aims to: 1) provide a framework for understanding the nature of onshore well blowouts, 2) quantify the incidence of such events for three specific geographic regions of Texas, 3) relate this data to CCUS and findings from other studies, and 4) explore the potential implications for public perception of this risk associated with CCUS projects. While quantifying answers to these questions proved to be challenging, the results from this study suggest that (1) the perceived risk of CO₂ well blowouts may exceed the statistical risk and (2) information that could be used to address this gap could be made more readily available to the greater benefit of industry and stakeholders who support the development of CCUS as an option for addressing anthropogenic CO₂ emissions. The study also suggests approaches to best conduct such data inquiries.

  18. Toward a self-consistent model of the interaction between an ultra-intense, normally incident laser pulse with an overdense plasma

    SciTech Connect (OSTI)

    Debayle, A.; ETSI Aeronáuticos. Universidad Politécnica de Madrid, Madrid 28040 ; Sanz, J.; Gremillet, L.; Mima, K.

    2013-05-15

    Following a recent work by Sanz et al. [Phys. Rev. E 85, 046411 (2012)], we elaborate upon a one-dimensional model describing the interaction between an ultra-intense, normally incident laser pulse and an overdense plasma. The analytical solutions of the reflected laser field, the electrostatic field, and the plasma surface oscillation are obtained within the cold-fluid approximation. The high-order harmonic spectrum is calculated from the exact solution of the plasma surface oscillations. In agreement with particle-in-cell simulations, two regimes of harmonic generation are predicted: for moderately relativistic laser intensities, or high plasma densities, the harmonic spectrum is determined by the discontinuity in the derivative of the reflected field when the electron plasma boundary oscillates across the fixed ion boundary. For higher intensities, the electron plasma boundary is confined inside the ion region and oscillates at relativistic velocities, giving rise to a train of reflected attosecond pulses. In both cases, the harmonic spectrum obeys an asymptotic ω{sup −4} scaling. The acceleration of electrons and the related laser absorption efficiency are computed by a test particle method. The model self-consistently reproduces the transition between the “anomalous skin effect” and the “J × B” heating predicted by particle-in-cell simulations. Analytical estimates of the different scalings are presented.

  19. Can we treat CO₂ well blowouts like routine plumbing problems? A study of the incidence, impact, and perception of loss of well control

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Porse, Sean L.; Wade, Sarah; Hovorka, Susan D.

    2014-12-31

    Risk communication literature suggests that for a number of reasons, the public may perceive a risk to be greater than indicated by its statistical probability. Public concern over risk can lead to significant and costly delays in project permitting and operations. Considering these theories, media coverage of CO₂-related well blowouts in 2013 gave rise to the questions: What is the risk of CO₂ well blowouts associated with CCUS through CO₂ EOR? What is the potential public perception of those risks? What information could be used to respond to public concern? To address these questions, this study aims to: 1) providemore » a framework for understanding the nature of onshore well blowouts, 2) quantify the incidence of such events for three specific geographic regions of Texas, 3) relate this data to CCUS and findings from other studies, and 4) explore the potential implications for public perception of this risk associated with CCUS projects. While quantifying answers to these questions proved to be challenging, the results from this study suggest that (1) the perceived risk of CO₂ well blowouts may exceed the statistical risk and (2) information that could be used to address this gap could be made more readily available to the greater benefit of industry and stakeholders who support the development of CCUS as an option for addressing anthropogenic CO₂ emissions. The study also suggests approaches to best conduct such data inquiries.« less

  20. High-resolution grazing-incidence grating spectrometer for temperature measurements of low-Z ions emitting in the 100–300 Å spectral band

    SciTech Connect (OSTI)

    Widmann, K. Beiersdorfer, P.; Magee, E. W.; Boyle, D. P.; Kaita, R.; Majeski, R.

    2014-11-15

    We have constructed a high-resolution grazing-incidence spectrometer designed for measuring the ion temperature of low-Z elements, such as Li{sup +} or Li{sup 2+}, which radiate near 199 Å and 135 Å, respectively. Based on measurements at the Livermore Electron Beam Ion Trap we have shown that the instrumental resolution is better than 48 mÅ at the 200 Å setting and better than 40 mÅ for the 135-Å range. Such a high spectral resolution corresponds to an instrumental limit for line-width based temperature measurements of about 45 eV for the 199 Å Li{sup +} and 65 eV for the 135 Å Li{sup 2+} lines. Recently obtained survey spectra from the Lithium Tokamak Experiment at the Princeton Plasma Physics Laboratory show the presence of these lithium emission lines and the expected core ion temperature of approximately 70 eV is sufficiently high to demonstrate the feasibility of utilizing our high-resolution spectrometer as an ion-temperature diagnostic.

  1. Scrambled and fried: Cigarette smoke exposure causes antral follicle destruction and oocyte dysfunction through oxidative stress

    SciTech Connect (OSTI)

    Sobinoff, A.P.; Beckett, E.L.; Jarnicki, A.G.; Sutherland, J.M.; McCluskey, A.; Hansbro, P.M.; McLaughlin, E.A.

    2013-09-01

    Cigarette smoke is a reproductive hazard associated with pre-mature reproductive senescence and reduced clinical pregnancy rates in female smokers. Despite an increased awareness of the adverse effects of cigarette smoke exposure on systemic health, many women remain unaware of the adverse effects of cigarette smoke on female fertility. This issue is compounded by our limited understanding of the molecular mechanisms behind cigarette smoke induced infertility. In this study we used a direct nasal exposure mouse model of cigarette smoke-induced chronic obstructive pulmonary disease to characterise mechanisms of cigarette-smoke induced ovotoxicity. Cigarette smoke exposure caused increased levels of primordial follicle depletion, antral follicle oocyte apoptosis and oxidative stress in exposed ovaries, resulting in fewer follicles available for ovulation. Evidence of oxidative stress also persisted in ovulated oocytes which escaped destruction, with increased levels of mitochondrial ROS and lipid peroxidation resulting in reduced fertilisation potential. Microarray analysis of ovarian tissue correlated these insults with a complex mechanism of ovotoxicity involving genes associated with detoxification, inflammation, follicular activation, immune cell mediated apoptosis and membrane organisation. In particular, the phase I detoxifying enzyme cyp2e1 was found to be significantly up-regulated in developing oocytes; an enzyme known to cause molecular bioactivation resulting in oxidative stress. Our results provide a preliminary model of cigarette smoke induced sub-fertility through cyp2e1 bioactivation and oxidative stress, resulting in developing follicle depletion and oocyte dysfunction. - Highlights: Cigarette smoke exposure targets developing follicle oocytes. The antral follicle oocyte is a primary site of ovarian cigarette smoke metabolism. Cyp2e1 is a major enzyme involved in ameliorating smoke-induced ovotoxicity. Cigarette smoke causes oocyte

  2. Chronic subhepatotoxic exposure to arsenic enhances hepatic injury caused by high fat diet in mice

    SciTech Connect (OSTI)

    Tan, Min; Schmidt, Robin H.; Beier, Juliane I.; Department of Medicine, University of Louisville Health Sciences Center, Louisville, KY 40292 ; Watson, Walter H.; University of Louisville Alcohol Research Center, University of Louisville Health Sciences Center, Louisville, KY 40292 ; Zhong, Hai; University of Louisville Alcohol Research Center, University of Louisville Health Sciences Center, Louisville, KY 40292 ; States, J. Christopher; Arteel, Gavin E.

    2011-12-15

    Arsenic is a ubiquitous contaminant in drinking water. Whereas arsenic can be directly hepatotoxic, the concentrations/doses required are generally higher than present in the US water supply. However, physiological/biochemical changes that are alone pathologically inert can enhance the hepatotoxic response to a subsequent stimulus. Such a '2-hit' paradigm is best exemplified in chronic fatty liver diseases. Here, the hypothesis that low arsenic exposure sensitizes liver to hepatotoxicity in a mouse model of non-alcoholic fatty liver disease was tested. Accordingly, male C57Bl/6J mice were exposed to low fat diet (LFD; 13% calories as fat) or high fat diet (HFD; 42% calories as fat) and tap water or arsenic (4.9 ppm as sodium arsenite) for ten weeks. Biochemical and histologic indices of liver damage were determined. High fat diet ({+-} arsenic) significantly increased body weight gain in mice compared with low-fat controls. HFD significantly increased liver to body weight ratios; this variable was unaffected by arsenic exposure. HFD caused steatohepatitis, as indicated by histological assessment and by increases in plasma ALT and AST. Although arsenic exposure had no effect on indices of liver damage in LFD-fed animals, it significantly increased the liver damage caused by HFD. This effect of arsenic correlated with enhanced inflammation and fibrin extracellular matrix (ECM) deposition. These data indicate that subhepatotoxic arsenic exposure enhances the toxicity of HFD. These results also suggest that arsenic exposure might be a risk factor for the development of fatty liver disease in human populations. -- Highlights: Black-Right-Pointing-Pointer Characterizes a mouse model of arsenic enhanced NAFLD. Black-Right-Pointing-Pointer Arsenic synergistically enhances experimental fatty liver disease at concentrations that cause no overt hepatotoxicity alone. Black-Right-Pointing-Pointer This effect is associated with increased inflammation.

  3. Life-threatening Cerebral Edema Caused by Acute Occlusion of a Superior Vena Cava Stent

    SciTech Connect (OSTI)

    Sofue, Keitaro Takeuchi, Yoshito Arai, Yasuaki; Sugimura, Kazuro

    2013-02-15

    A71-year-old man with advanced lung cancer developed a life-threatening cerebral edema caused by the acute occlusion of a superior vena cava (SVC) stent and was successfully treated by an additional stent placement. Although stent occlusion is a common early complication, no life-threatening situations have been reported until now. Our experience highlights the fact that acute stent occlusion can potentially lead to the complete venous shutdown of the SVC, resulting in life-threatening cerebral edema, after SVC stent placement. Immediate diagnosis and countermeasures are required.

  4. Remote reactor repair: GTA (gas tungsten Arc) weld cracking caused by entrapped helium

    SciTech Connect (OSTI)

    Kanne, W.R. Jr.

    1988-01-01

    A repair patch was welded to the wall of a nuclear reactor tank using remotely controlled thirty-foot long robot arms. Further repair was halted when gas tungsten arc (GTA) welds joining type 304L stainless steel patches to the 304 stainless steel wall developed toe cracks in the heat-affected zone (HAZ). The role of helium in cracking was investigated using material with entrapped helium from tritium decay. As a result of this investigation, and of an extensive array of diagnostic tests performed on reactor tank wall material, helium embrittlement was shown to be the cause of the toe cracks.

  5. Hanford Single-Shell Tank Leak Causes and Locations - 241-BY and 241-TY Farm

    SciTech Connect (OSTI)

    Girardot, Crystal L.; Harlow, Donald G.

    2014-09-04

    This document identifies 241-BY Tank Farm (BY Farm) and 241-TY Tank Farm (TY Farm) lead causes and locations for the 100 series leaking tanks (241-BY-103, 241-TY-103, 241-TY-104, 241-TY-105 and 241-TY-106) identified in RPP-RPT-43704, Hanford BY Farm Leak Assessments Report, and in RPP-RPT-42296, Hanford TY Farm Leak Assessments Report. This document satisfies the BY and TY Farm portion of the target (T04) in the Hanford Federal Facility Agreement and Consent Order milestone M-045-91F.

  6. Hanford Single-Shell Tank Leak Causes and Locations - 241-BY and 241-TY Farm

    SciTech Connect (OSTI)

    Girardot, Crystal L.; Harlow, Donald G.

    2013-11-19

    This document identifies 241-BY Tank Farm (BY Farm) and 241-TY Tank Farm (TY Farm) leak causes and locations for the 100 series leaking tanks (241-BY-103, 241-TY-103, 241-TY-104, 241-TY-105, and 241-TY-106) identified in RPP-RPT-43704, Hanford BY Farm Leak Assessments Report, and in RPP-RPT-42296, Hanford TY Farm Leak Assessments Report. This document satisfies the BY and TY Farm portion of the target (T04) in Hanford Federal Facility Agreement and Consent Order milestone M-045-91F.

  7. Interfacial Electron-Phonon Coupling as the Cause of Enhanced Tc in

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Single-layer FeSe Films on SrTiO3 | Stanford Synchrotron Radiation Lightsource Interfacial Electron-Phonon Coupling as the Cause of Enhanced Tc in Single-layer FeSe Films on SrTiO3 Friday, February 27, 2015 In the past several years, multiple studies have confirmed superconductivity in single-unit-cell-thick films of iron selenide (1UC FeSe) grown on strontium titanate (STO), with gap opening temperatures approaching the boiling point of liquid nitrogen, which is nearly a decade higher than

  8. Hanford Single-Shell Tank Leak Causes and Locations - 241-SX Farm

    SciTech Connect (OSTI)

    Girardot, Crystal L.; Harlow, Donald G.

    2014-01-08

    This document identifies 241-SX Tank Farm (SX Farm) leak causes and locations for the 100 series leaking tanks (241-SX-107, 241-SX-108, 241-SX-109, 241-SX-111, 241-SX-112, 241-SX-113, 241-SX-114, and 241-SX-115) identified in RPP-ENV-39658, Rev. 0, Hanford SX-Farm Leak Assessments Report. This document satisfies the SX Farm portion of the target (T04) in the Hanford Federal Facility Agreement and Consent Order milestone M-045-91F.

  9. Dried plum diet protects from bone loss caused by ionizing radiation

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Schreurs, A. -S.; Shirazi-Fard, Y.; Shahnazari, M.; Alwood, J. S.; Truong, T. A.; Tahimic, C. G. T.; Limoli, C. L.; Turner, N. D.; Halloran, B.; Globus, R. K.

    2016-02-11

    Bone loss caused by ionizing radiation is a potential health concern for radiotherapy patients, radiation workers and astronauts. In animal studies, exposure to ionizing radiation increases oxidative damage in skeletal tissues, and results in an imbalance in bone remodeling initiated by increased bone-resorbing osteoclasts. Therefore, we evaluated various candidate interventions with antioxidant or antiinflammatory activities (antioxidant cocktail, dihydrolipoic acid, ibuprofen, dried plum) both for their ability to blunt the expression of resorption-related genes in marrow cells after irradiation with either gamma rays (photons, 2 Gy) or simulated space radiation (protons and heavy ions, 1 Gy) and to prevent bone loss.more » Dried plum was most effective in reducing the expression of genes related to bone resorption (Nfe2l2, Rankl, Mcp1, Opg, TNF-α) and also preventing later cancellous bone decrements caused by irradiation with either photons or heavy ions. Furthermore, dietary supplementation with DP may prevent the skeletal effects of radiation exposures either in space or on Earth.« less

  10. Enhanced superbanana transport caused by chaotic scattering across an asymmetric separatrix

    SciTech Connect (OSTI)

    Dubin, Daniel H. E.; Kabantsev, A. A.; Driscoll, C. F.

    2012-05-15

    This paper discusses a novel 'chaotic' form of superbanana transport and compares the theory to experiments on non-neutral plasmas. Superbanana transport is caused by particles that cross local trapping separatrices (magnetic or electric ripples) in the presence of field 'errors' such as toroidal magnetic curvature. Traditionally, collisions (at rate {nu}) cause separatrix crossings, with resulting transport that scales as {nu}{sup 1/2}B{sup -1/2}. The 'chaotic' transport of interest here occurs when the separatrix is 'ruffled' in the direction of plasma drift; then, collisionless particle orbits give random trapping and detrapping. Prior theory assumed a 'stellarator symmetry' and suggested that these orbits give reduced transport scaling as {nu}{sup p} with p{approx}1. Here, we fully characterize chaotic transport and show that the transport is enhanced rather than reduced, scaling as {nu}{sup 0}B{sup -1}. Experiments on pure electron plasmas provide quantitative transport measurements, with precise control of the overall field error, and of the trapping separatrix with and without ruffles. The experiments show close agreement with theory over a decade in B, for both collisional neoclassical transport, and for the distinctive chaotic transport. At low magnetic fields, transport scaling as B{sup -p} with p>rsim2 becomes dominant, showing preliminary agreement with bounce-resonant theory.

  11. A mutation causing Alport syndrome with tardive hearing loss is common in the western United States

    SciTech Connect (OSTI)

    Barker, D.F.; Denison, J.C.; Atkin, C.L.

    1996-06-01

    Mutations in the COL4A5 gene, located at Xq22, cause Alport syndrome (AS), a nephritis characterized by progressive deterioration of the glomerular basement membrane and usually associated with progressive hearing loss. We have identified a novel mutation, L1649R, present in 9 of 121 independently ascertained families. Affected males shared the same haplotype of eight polymorphic markers tightly linked to COL4A5, indicating common ancestry. Genealogical studies place the birth of this ancestor >200 years ago. The L1649R mutation is a relatively common cause of Alport syndrome in the western United States, in part because of the rapid growth and migratory expansion of mid-nineteenth-century pioneer populations carrying the gene. L1649R affects a highly conserved residue in the NC1 domain, which is involved in key inter- and intramolecular interactions, but results in a relatively mild disease phenotype. Renal failure in an L1649R male typically occurs in the 4th or 5th decade and precedes the onset of significant hearing loss by {approximately}10 years. 45 refs., 5 figs.

  12. Identifying the Root Causes of Wait States in Large-Scale Parallel Applications

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Böhme, David; Geimer, Markus; Arnold, Lukas; Voigtlaender, Felix; Wolf, Felix

    2016-07-20

    Driven by growing application requirements and accelerated by current trends in microprocessor design, the number of processor cores on modern supercomputers is increasing from generation to generation. However, load or communication imbalance prevents many codes from taking advantage of the available parallelism, as delays of single processes may spread wait states across the entire machine. Moreover, when employing complex point-to-point communication patterns, wait states may propagate along far-reaching cause-effect chains that are hard to track manually and that complicate an assessment of the actual costs of an imbalance. Building on earlier work by Meira Jr. et al., we present amore » scalable approach that identifies program wait states and attributes their costs in terms of resource waste to their original cause. Ultimately, by replaying event traces in parallel both forward and backward, we can identify the processes and call paths responsible for the most severe imbalances even for runs with hundreds of thousands of processes.« less

  13. Influence of a Weak Field of Pulsed DC Electricity on the Behavior and Incidence of Injury in Adult Steelhead and Pacific Lamprey, Final Report.

    SciTech Connect (OSTI)

    Mesa, Matthew

    2009-02-13

    electrofishing operations typically use high voltage and amperage settings and a variety of waveforms, pulse widths (PW), and pulse frequencies (PF), depending on conditions and target species. For example, when backpack electrofishing for trout in a small stream, one might use settings such as 500 V pulsed DC, a PW of 1 ms, and a PF of 60 Hz. In contrast, the electrical barrier proposed by SRI will produce electrical conditions significantly lower than those used in electrofishing, particularly for PW and PF (e.g., PW ranging from 300-1,000 {micro}s and PF from 2-3 Hz). Further, voltage gradients (in V/cm) are predicted to be lower in the electric barrier than those produced during typical electrofishing. Although the relatively weak, pulsed DC electric fields to be produced by the barrier may be effective at deterring pinnipeds, little, if anything, is known about the effects of such low intensity electrical fields on fish behavior. For this research, we evaluated the effects of weak, pulsed DC electric currents on the behavior of adult steelhead and Pacific lamprey and the incidence of injury in steelhead only. In a series of laboratory experiments, we: (1) documented the rate of passage of fish over miniature, prototype electric barriers when they were on and off; (2) determined some electric thresholds beyond which fish would not pass over the barrier; and (3) assessed the incidence and severity of injury in steelhead exposed to relatively severe electrical conditions. The results of this study should be useful for making decisions about whether to install electrical barriers in the lower Columbia River, or elsewhere, to reduce predation on upstream migrating salmonids and other fishes by marine pinnipeds.

  14. Low Group Delay Dispersion Optical Coating for Broad Bandwidth High Reflection at 45° Incidence, P Polarization of Femtosecond Pulses with 900 nm Center Wavelength

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Bellum, John C.; Field, Ella S.; Winstone, Trevor B.; Kletecka, Damon E.

    2016-03-01

    We describe an optical coating design suitable for broad bandwidth high reflection (BBHR) at 45° angle of incidence (AOI), P polarization (Ppol) of femtosecond (fs) laser pulses whose wavelengths range from 800 to 1000 nm. The design process is guided by quarter-wave HR coating properties. Our design must afford low group delay dispersion (GDD) for reflected light over the broad, 200 nm bandwidth in order to minimize temporal broadening of the fs pulses due to dispersive alteration of relative phases between their frequency components. The design should also be favorable to high laser-induced damage threshold (LIDT). We base the coatingmore » on TiO2/SiO2 layer pairs produced by means of e-beam evaporation with ion-assisted deposition, and use OptiLayer Thin Film Software to explore designs starting with TiO2/SiO2 layers having thicknesses in a reverse chirped arrangement. This approach led to a design with R > 99% from 800 to 1000 nm and GDD < 20 fs2 from 843 to 949 nm (45° AOI, Ppol). The design’s GDD behaves in a smooth way, suitable for GDD compensation techniques, and its electric field intensities show promise for high LIDTs. Reflectivity and GDD measurements for the initial test coating indicate good performance of the BBHR design. Subsequent coating runs with improved process calibration produced two coatings whose HR bands satisfactorily meet the design goals. Lastly, for the sake of completeness, we summarize our previously reported transmission spectra and LIDT test results with 800 ps, 8 ps and 675 fs pulses for these two coatings, and present a table of the LIDT results we have for all of our TiO2/SiO2 BBHR coatings, showing the trends with test laser pulse duration from the ns to sub-ps regimes.« less

  15. Study of interface correlation in W/C multilayer structure by specular and non-specular grazing incidence X-ray reflectivity measurements

    SciTech Connect (OSTI)

    Biswas, A. Bhattacharyya, D.; Sahoo, N. K.; Maidul Haque, S.; Tripathi, S.; De, Rajnarayan; Rai, S.

    2015-10-28

    W/C/W tri-layer thin film samples have been deposited on c-Si substrates in a home-built Ion Beam Sputtering system at 1.5 × 10{sup −3} Torr Ar working pressure and 10 mA grid current. The tri-layer samples have been deposited at different Ar{sup +} ion energies between 0.6 and 1.2 keV for W layer deposition and the samples have been characterized by specular and non-specular grazing incidence X-ray reflectivity (GIXR) measurements. By analyzing the GIXR spectra, various interface parameters have been obtained for both W-on-C and C-on-W interfaces and optimum Ar{sup +} ion energy for obtaining interfaces with low imperfections has been found. Subsequently, multilayer W/C samples with 5-layer, 7-layer, 9-layer, and 13-layer have been deposited at this optimum Ar{sup +} ion energy. By fitting the specular and diffused GIXR data of the multilayer samples with the parameters of each interface as fitting variables, different interface parameters, viz., interface width, in-plane correlation length, interface roughness, and interface diffusion have been estimated for each interface and their variation across the depth of the multilayers have been obtained. The information would be useful in realizing W/C multilayers for soft X-ray mirror application in the <100 Å wavelength regime. The applicability of the “restart of the growth at the interface” model in the case of these ion beam sputter deposited W/C multilayers has also been investigated in the course of this study.

  16. Subclavian Artery Occlusion and Pseudoaneurysm Caused by Lung Apex Mucormycosis: Successful Treatment with Transcatheter Embolization

    SciTech Connect (OSTI)

    Economopoulos, Nikolaos; Kelekis, Dimitris; Papadopoulos, Antonios; Kontopoulou, Christina; Brountzos, Elias N.

    2007-02-15

    Subclavian artery pseudoaneurysm and occlusion in young patients are usually post-traumatic. We report the case of a 33-year-old diabetic woman with subclavian artery occlusion and pseudoaneurysm formation caused by pulmonary mucormycosis infection. The patient presented with diabetic ketoacidosis, Horner's syndrome, and absent left arm pulses. A cystic lesion of the left lung apex was found by imaging, was surgically resected, and was histologically diagnosed as mucormycosis infection. Magnetic resonance angiography depicted a left subclavian artery pseudoaneurysm and occlusion adjacent to the mucormycosis lesion. To protect against thromboembolic complications and rupture, the pseudoaneurysm was embolized with coils. The patient is clinically well 1 year after the intervention with no perfusion of the pseudoaneurysm.

  17. Linear magnetoresistance caused by mobility fluctuations in n-doped Cd3As2

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Narayanan, A.; Watson, M. D.; Blake, S. F.; Bruyant, N.; Drigo, L.; Chen, Y. L.; Prabhakaran, D.; Yan, B.; Felser, C.; Kong, T.; et al

    2015-03-19

    Cd3As2 is a candidate three-dimensional Dirac semimetal which has exceedingly high mobility and nonsaturating linear magnetoresistance that may be relevant for future practical applications. We report magnetotransport and tunnel diode oscillation measurements on Cd3As2, in magnetic fields up to 65 T and temperatures between 1.5 and 300 K. We find that the nonsaturating linear magnetoresistance persists up to 65 T and it is likely caused by disorder effects, as it scales with the high mobility rather than directly linked to Fermi surface changes even when approaching the quantum limit. As a result of the observed quantum oscillations, we determine themore » bulk three-dimensional Fermi surface having signatures of Dirac behavior with a nontrivial Berry phase shift, very light effective quasiparticle masses, and clear deviations from the band-structure predictions. In very high fields we also detect signatures of large Zeeman spin splitting (g~16).« less

  18. Causes of Ocean Surface temperature Changes in Atlantic andPacific Topical Cyclogenesis Regions

    SciTech Connect (OSTI)

    Santer, B.D.; Wigley, T.M.L.; Gleckler, P.J.; Bonfils, C.; Wehner, M.F.; AchutaRao, K.; Barnett, T.P.; Boyle, J.S.; Bruggemann, W.; Fiorino, M.; Gillett, N.; Hansen, J.E.; Jones, P.D.; Klein, S.A.; Meehl,G.A.; Raper, S.C.B.; Reynolds, R.W.; Stott, P.A.; Taylor, K.E.; Washington, W.M.

    2006-01-31

    Previous research has identified links between changes in sea surface temperature (SST) and hurricane intensity. We use climate models to study the possible causes of SST changes in Atlantic and Pacific tropical cyclogenesis regions. The observed SST increases in these regions range from 0.32 to 0.67 C over the 20th century. The 22 climate models examined here suggest that century-timescale SST changes of this magnitude cannot be explained solely by unforced variability of the climate system, even under conservative assumptions regarding the magnitude of this variability. Model simulations that include external forcing by combined anthropogenic and natural factors are generally capable of replicating observed SST changes in both tropical cyclogenesis regions.

  19. Analysis of ammonium sulfate circulation tank failure -- Possible causes and their remediation

    SciTech Connect (OSTI)

    O`Hearn, R.J.

    1997-12-31

    Acme steel manufactures a liquid solution of ammonium sulphate by scrubbing the coke oven gas with a dilute solution of sulphuric acid. When the bath reaches a predetermined specific gravity, it is isolated from the system, neutralized with aqua ammonia, pumped to the shipping tanks, re-charged with water and acid, then placed back in service. To improve the ammonia removal efficiency, three circulation tanks are used in this system. In June 1996, the volume of two of the sulfate solution tanks in the ammonia removal plant were increased by two different pressure events. The first tank was damaged by pressure that was not relieved due to a plugged vent line. The second tank was damaged by a pressure event generated during the process of making ammonium sulfate. This paper will discuss the cause of the second tank`s failure, and the design solution to restart the operation of the plant.

  20. On the possibilities of reduction in emission caused by home tile stoves in Cracow

    SciTech Connect (OSTI)

    Szewczyk, W.

    1995-12-31

    The coal-fired tile stoves are still very popular in Poland. The estimated total number of such home stoves operated in Cracow reaches ca. 100 000. Operation of these stoves during the heating season belongs to the most significant sources of air pollution. Type and scale of emission of the most important pollutants, caused by coal combustion in home stoves in Cracow has been determined basing upon the investigations carried out at the laboratory of the Department of Power Engineering Machines and Devices, Academy of Mining and Metallurgy, Cracow, Poland within the American-Polish Program of Elimination of Low Emission Sources in Cracow. Further experiments included in this Program allowed to estimate the attainable efficiency of home tile stoves and possible reduction in pollutant emission resulting from their operation. A short discussion of these data and capacities is presented in this lecture.

  1. Measurement and simulation of jet mass caused by a high-aspect ratio pertubation

    SciTech Connect (OSTI)

    Keiter, Paul A; Cooley, James; Kyrala, George; Wilson, Doug; Blue, Brent; Edwards, John; Robey, Harry; Spears, Brian

    2009-01-01

    Inertial confinement fusion (ICF) capsule performance can be negatively impacted by the presence of hydrodynamic instabilities. To perform a gas fill on an ICF capsule current plans involve drilling a small hole and inserting a fill tube to inject the gas mixture into the capsule. This introduces a perturbation on the capsule, which can seed hydrodynamic instabilities. The small hole can cause jetting of the shell material into the gas, which might adversely affect the capsule performance. We have performed simulations and experiments to study the hydrodynamic evolution of jets from high-aspect ratio holes, such as the fill tube hole. Although simulations using cold materials over predict the amount of mass in the jet, when a reasonable amount of preheat (< 1 eV) is introduced, the simulations are in better agreement with the experiment.

  2. Dosimetric effects caused by couch tops and immobilization devices: Report of AAPM Task Group 176

    SciTech Connect (OSTI)

    Olch, Arthur J.; Gerig, Lee; Li, Heng; Mihaylov, Ivaylo; Morgan, Andrew

    2014-06-15

    The dosimetric impact from devices external to the patient is a complex combination of increased skin dose, reduced tumor dose, and altered dose distribution. Although small monitor unit or dose corrections are routinely made for blocking trays, ion chamber correction factors, e.g., accounting for temperature and pressure, or tissue inhomogeneities, the dose perturbation of the treatment couch top or immobilization devices is often overlooked. These devices also increase skin dose, an effect which is also often ignored or underestimated. These concerns have grown recently due to the increased use of monolithic carbon fiber couch tops which are optimal for imaging for patient position verification but cause attenuation and increased skin dose compared to the “tennis racket” style couch top they often replace. Also, arc delivery techniques have replaced stationary gantry techniques which cause a greater fraction of the dose to be delivered from posterior angles. A host of immobilization devices are available and used to increase patient positioning reproducibility, and these also have attenuation and skin dose implications which are often ignored. This report of Task Group 176 serves to present a survey of published data that illustrates the magnitude of the dosimetric effects of a wide range of devices external to the patient. The report also provides methods for modeling couch tops in treatment planning systems so the physicist can accurately compute the dosimetric effects for indexed patient treatments. Both photon and proton beams are considered. A discussion on avoidance of high density structures during beam planning is also provided. An important aspect of this report are the recommendations the authors make to clinical physicists, treatment planning system vendors, and device vendors on how to make measurements of surface dose and attenuation and how to report these values. For the vendors, an appeal is made to work together to provide accurate couch top

  3. Social impacts of earthquakes caused by gas extraction in the Province of Groningen, The Netherlands

    SciTech Connect (OSTI)

    Voort, Nick van der Vanclay, Frank

    2015-01-15

    Gas extraction from the Groningen gasfield in the northern Netherlands has led to localised earthquakes which are projected to become more severe. The social impacts experienced by local residents include: damage to property; declining house prices; concerns about the chance of dykes breaking; feelings of anxiety and insecurity; health issues; and anger. These social and emotional impacts are exacerbated by the increasing distrust Groningen people have towards the national government and the gas company, NAM, a partnership between Shell and ExxonMobil. The earthquakes have reopened discussions about the distribution of benefits from gas production and the extent to which benefits are retained locally. Mitigation of the impacts is attempted, but the lack of trust decreases the effectiveness of the mitigation measures. The extent of this experience of previously-unforeseen, unanticipated impacts suggests that a new social and environmental impact assessment needs to be undertaken, and a new Social Impact Management Plan (SIMP) and Impacts and Benefits Agreement (IBA) developed, so that the project can regain its legitimacy and social licence to operate. In addition to conventional gas, this paper has wider relevance for unconventional gas developments, for example shale gas extraction by hydraulic fracturing methods (fracking). - Highlights: • Gas production in Groningen has caused over 1000 earthquakes. • The induced seismicity has caused many social impacts. • Impacts include building damage, reduced house prices, fear and health issues. • Mitigation measures attempted to date are inadequate. • Distrust towards the national government and operator hinders mitigation efforts. • Gas production in Groningen has lost its social licence to operate.

  4. Critical Causes of Degradation in Integrated Laboratory Scale Cells during High Temperature Electrolysis

    SciTech Connect (OSTI)

    M.S. Sohal; J.E. O'Brien; C.M. Stoots; J. J. Hartvigsen; D. Larsen; S. Elangovan; J.S. Herring; J.D. Carter; V.I. Sharma; B. Yildiz

    2009-05-01

    An ongoing project at Idaho National Laboratory involves generating hydrogen from steam using solid oxide electrolysis cells (SOEC). This report describes background information about SOECs, the Integrated Laboratory Scale (ILS) testing of solid-oxide electrolysis stacks, ILS performance degradation, and post-test examination of SOECs by various researchers. The ILS test was a 720- cell, three-module test comprised of 12 stacks of 60 cells each. A peak H2 production rate of 5.7 Nm3/hr was achieved. Initially, the module area-specific resistance ranged from 1.25 Ocm2 to just over 2 Ocm2. Total H2 production rate decreased from 5.7 Nm3/hr to a steady state value of 0.7 Nm3/hr. The decrease was primarily due to cell degradation. Post test examination by Ceramatec showed that the hydrogen electrode appeared to be in good condition. The oxygen evolution electrode does show delamination in operation and an apparent foreign layer deposited at the electrolyte interface. Post test examination by Argonne National Laboratory showed that the O2-electrode delaminated from the electrolyte near the edge. One possible reason for this delamination is excessive pressure buildup with high O2 flow in the over-sintered region. According to post test examination at the Massachusetts Institute of Technology, the electrochemical reactions have been recognized as one of the prevalent causes of their degradation. Specifically, two important degradation mechanisms were examined: (1) transport of Crcontaining species from steel interconnects into the oxygen electrode and LSC bond layers in SOECs, and (2) cation segregation and phase separation in the bond layer. INL conducted a workshop October 27, 2008 to discuss possible causes of degradation in a SOEC stack. Generally, it was agreed that the following are major degradation issues relating to SOECs: Delamination of the O2-electrode and bond layer on the steam/O2-electrode side Contaminants (Ni, Cr, Si, etc.) on reaction sites (triple

  5. Measurements of television interference caused by a vertical-axis wind machine. Final subcontract report

    SciTech Connect (OSTI)

    Sengupta, D L; Senior, T B.A.; Ferris, J E

    1983-01-01

    The electromagnetic interference to television reception caused by the 17 m Darreius at Albuquerque, NM, has been studied by carrying out measurements at a number of sites in the vicinity of the VAWT. The rf sources used were the commercial vhf and uhf TV signals available in the area. Ambient field-strength measurements showed that the signals on all TV channels except one were strong, and provided good reception at all test sites. With the antenna (properly) oriented for maximum direct signal, unacceptable interference was observed on some channels at sites out to 33 m from the WT in the forward and backward regions. With the antenna beam directed at the WT, interference varying from slight to violent were observed at all sites on some or all TV channels. A simple theoretical model has been developed for analyzing the TVI produced by a VAWT like the Darrieus. Using the model in conjunction with measured data, an approximate expression for the equivalent scattering area A of the Darrieus has been developed. It is found that A is wavelength (lambda) dependent and varies as lambda/sup 1/2/.

  6. Waterwall corrosion in pulverized coal burning boilers: root causes and wastage predictions

    SciTech Connect (OSTI)

    Bakker, W.; Stanko, G.; Blough, J.; Seitz, W.; Niksa, S.

    2007-07-01

    Waterwall corrosion has become a serious problem in the USA since the introduction of combustion systems, designed to lower NOx emissions. Previous papers have shown that the main cause of the increased corrosion is the deposition of corrodants, iron sulfides and alkali chlorides, which occurs under reducing conditions. In this paper, the contribution of various variables such as the amount of corrodant in the deposit, the flue gas composition and the metal temperature, is further quantified in laboratory tests, using a test furnace allowing thermal gradients across the deposit and the metal tube samples. Approximate deposit compositions were calculated from the coal composition, its associated ash constituents and corrosive impurities. A commercially available thermochemical equilibrium package was used, after modifications to reflect empirical alkali availability data. Predictions from these calculations agreed reasonably well with the alkali chloride and FeS content found in actual boiler deposits. Thus approximate corrosion rates can be predicted from the chemical composition of the coal using corrosion rates from laboratory tests, adjusted to account for the short duration (100 hours) of the laboratory tests. Reasonable agreement was again obtained between actual and predicted results.

  7. Innovative Approach to Establish Root Causes for Cracking in Aggressive Reactor Environments

    SciTech Connect (OSTI)

    Bruemmer, Stephen M.; Thomas, Larry E.; Vetrano, John S.; Simonen, Edward P.

    2003-10-31

    The research focuses on the high-resolution characterization of degradation microstructures and microchemistries in specimens tested under controlled conditions for the environment and for the material where in-service complexities can be minimized. Thermodynamic and kinetic modeling of crack-tip processes is employed to analyze corrosion-induced structures and gain insights into degradation mechanisms. Novel mechanistic ''fingerprinting'' of crack-tip structures is used to isolate causes of environmental cracking in tandem with quantitative measurements of crack growth. Sample preparation methods and advanced analytical techniques are used to characterize corrosion/oxidation reactions and crack-tip structures at near atomic dimensions in order to gain insight into fundamental environmental cracking mechanisms. Reactions at buried interfaces, not accessible by conventional approaches, are being systematically interrogated. Crack-growth experiments in high-temperature water environments are evaluating and isolating the effects of material condition (matrix strength, grain boundary composition and precipitation) on stress corrosion cracking (SCC). The fundamental understanding of crack advance mechanisms will establish the basis to design new corrosion-resistant alloys for current light-water reactors and advanced reactor systems.

  8. Reliability enhancement of APR + diverse protection system regarding common cause failures

    SciTech Connect (OSTI)

    Oh, Y. G.; Kim, Y. M.; Yim, H. S.; Lee, S. J.

    2012-07-01

    The Advanced Power Reactor Plus (APR +) nuclear power plant design has been developed on the basis of the APR1400 (Advanced Power Reactor 1400 MWe) to further enhance safety and economics. For the mitigation of Anticipated Transients Without Scram (ATWS) as well as Common Cause Failures (CCF) within the Plant Protection System (PPS) and the Emergency Safety Feature - Component Control System (ESF-CCS), several design improvement features have been implemented for the Diverse Protection System (DPS) of the APR + plant. As compared to the APR1400 DPS design, the APR + DPS has been designed to provide the Safety Injection Actuation Signal (SIAS) considering a large break LOCA accident concurrent with the CCF. Additionally several design improvement features, such as channel structure with redundant processing modules, and changes of system communication methods and auto-system test methods, are introduced to enhance the functional reliability of the DPS. Therefore, it is expected that the APR + DPS can provide an enhanced safety and reliability regarding possible CCF in the safety-grade I and C systems as well as the DPS itself. (authors)

  9. Management of wildlife causing damage at Argonne National Laboratory-East, DuPage County, Illinois

    SciTech Connect (OSTI)

    1995-04-01

    The DOE, after an independent review, has adopted an Environmental Assessment (EA) prepared by the US Department of Agriculture (USDA) which evaluates use of an Integrated Wildlife Damage Management approach at Argonne National Laboratory-East (ANL-E) in DuPage County, Illinois (April 1995). In 1994, the USDA issued a programmatic Environmental Impact Statement (EIS) that covers nationwide animal damage control activities. The EA for Management of Wildlife Causing Damage at ANL-E tiers off this programmatic EIS. The USDA wrote the EA as a result of DOE`s request to USDA to prepare and implement a comprehensive Wildlife Management Damage Plan; the USDA has authority for animal damage control under the Animal Damage Control Act of 1931, as amended, and the Rural Development, Agriculture and Related Agencies Appropriations Act of 1988. DOE has determined, based on the analysis in the EA, that the proposed action does not constitute a major Federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act of 1969 (NEPA). Therefore, the preparation of an EIS is not required. This report contains the Environmental Assessment, as well as the Finding of No Significant Impact (FONSI).

  10. A theoretical model of subsidence caused by petroleum production: Big Hill Field, Jefferson County, Texas

    SciTech Connect (OSTI)

    Hill, D.W.; Sharp, J.M. Jr. . Dept. of Geological Sciences)

    1993-02-01

    In the Texas Gulf Coastal Plain, there is a history of oil and gas production extending over 2 to 5 decades. Concurrent with this production history, there has been unprecedented population growth accompanied by vastly increased groundwater demands. Land subsidence on both local and regional bases in this geologic province has been measured and predicted in several studies. The vast majority of these studies have addressed the problem from the standpoint of groundwater usage while only a few have considered the effects of oil and gas production. Based upon field-based computational techniques (Helm, 1984), a model has been developed to predict land subsidence caused by oil and gas production. This method is applied to the Big Hill Field in Jefferson County, Texas. Inputs include production data from a series of wells in this field and lithologic data from electric logs of these same wells. Outputs include predicted amounts of subsidence, the time frame of subsidence, and sensitivity analyses of compressibility and hydraulic conductivity estimates. Depending upon estimated compressibility, subsidence, to date, is predicted to be as high as 20 cm. Similarly, depending upon estimated vertical hydraulic conductivity, the time frame may be decades for this subsidence. These same methods can be applied to other oil/gas fields with established production histories as well as new fields when production scenarios are assumed. Where subsidence has been carefully measured above petroleum reservoir, the model may be used inversely to calculate sediment compressibilities.

  11. QUASI-BIENNIAL OSCILLATIONS IN THE SOLAR TACHOCLINE CAUSED BY MAGNETIC ROSSBY WAVE INSTABILITIES

    SciTech Connect (OSTI)

    Zaqarashvili, Teimuraz V.; Carbonell, Marc; Oliver, Ramon; Ballester, Jose Luis E-mail: marc.carbonell@uib.e E-mail: joseluis.ballester@uib.e

    2010-11-20

    Quasi-biennial oscillations (QBOs) are frequently observed in solar activity indices. However, no clear physical mechanism for the observed variations has been suggested so far. Here, we study the stability of magnetic Rossby waves in the solar tachocline using the shallow water magnetohydrodynamic approximation. Our analysis shows that the combination of typical differential rotation and a toroidal magnetic field with a strength of {>=}10{sup 5} G triggers the instability of the m = 1 magnetic Rossby wave harmonic with a period of {approx}2 years. This harmonic is antisymmetric with respect to the equator and its period (and growth rate) depends on the differential rotation parameters and magnetic field strength. The oscillations may cause a periodic magnetic flux emergence at the solar surface and consequently may lead to the observed QBO in solar activity features. The period of QBOs may change throughout a cycle, and from cycle to cycle, due to variations of the mean magnetic field and differential rotation in the tachocline.

  12. Diagnosing the Causes and Severity of One-sided Message Contention

    SciTech Connect (OSTI)

    Tallent, Nathan R.; Vishnu, Abhinav; van Dam, Hubertus; Daily, Jeffrey A.; Kerbyson, Darren J.; Hoisie, Adolfy

    2015-02-11

    Two trends suggest network contention for one-sided messages is poised to become a performance problem that concerns application developers: an increased interest in one-sided programming models and a rising ratio of hardware threads to network injection bandwidth. Unfortunately, it is difficult to reason about network contention and one-sided messages because one-sided tasks can either decrease or increase contention. We present effective and portable techniques for diagnosing the causes and severity of one-sided message contention. To detect that a message is affected by contention, we maintain statistics representing instantaneous (non-local) network resource demand. Using lightweight measurement and modeling, we identify the portion of a message's latency that is due to contention and whether contention occurs at the initiator or target. We attribute these metrics to program statements in their full static and dynamic context. We characterize contention for an important computational chemistry benchmark on InfiniBand, Cray Aries, and IBM Blue Gene/Q interconnects. We pinpoint the sources of contention, estimate their severity, and show that when message delivery time deviates from an ideal model, there are other messages contending for the same network links. With a small change to the benchmark, we reduce contention up to 50% and improve total runtime as much as 20%.

  13. Prevention of Prespawning Mortality: Cause of Salmon Headburns and Cranial Lesions

    SciTech Connect (OSTI)

    Neitzel, Duane A.; Elston, R A.; Abernethy, Cary S.

    2004-06-01

    This project was to undertaken to provide information about a condition known as ''headburn''. Information from the project will enable U.S. Corps of Engineers managers to make adjustments in operational procedures or facilities on the Columbia and Snake rivers to prevent loss of pre-spawning adult salmonids that migrate through the facilities. Headburn is a descriptive clinical term used by fishery biologists to describe scalping or exfoliation of skin and ulceration of underlying connective tissue and muscle, primarily of the jaw and cranial region of salmonids observed at fish passage facilities. Headburn lesions are primarily caused when fish collide with concrete or other structures at dams and fish passage facilities, and may be exacerbated in some fish that ''fallback'' or pass over spillways or through turbine assemblies after having passed the dam through a fish ladder. Prespawning mortality of headburned salmonids can be prevented or greatly reduced by therapeutic treatment of both hatchery and wild fish. Treatments would consist of topical application of an anti-fungal agent, injection of replacement plasma electrolytes into the peritoneal cavity, and injection of a broad-spectrum antibacterial agent at fish passage and trapping facilities or hatcheries.

  14. Blackout 2003: Final Report on the August 14, 2003 Blackout in the United States and Canada: Causes and Recommendations

    Office of Energy Efficiency and Renewable Energy (EERE)

    The Task Force has completed a thorough investigation of the causes of the August 14, 2003 blackout and has recommended actions to minimize the likelihood and scope of similar events in the future.

  15. Single-Shell Tanks Leak Integrity Elements/ SX Farm Leak Causes and Locations - 12127

    SciTech Connect (OSTI)

    Girardot, Crystal; Harlow, Don; Venetz, Theodore; Washenfelder, Dennis; Johnson, Jeremy

    2012-07-01

    Washington River Protection Solutions, LLC (WRPS) developed an enhanced single-shell tank (SST) integrity project in 2009. An expert panel on SST integrity was created to provide recommendations supporting the development of the project. One primary recommendation was to expand the leak assessment reports (substitute report or LD-1) to include leak causes and locations. The recommendation has been included in the M-045-91F Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement) as one of four targets relating to SST leak integrity. The 241-SX Farm (SX Farm) tanks with leak losses were addressed on an individual tank basis as part of LD-1. Currently, 8 out of 23 SSTs that have been reported to having a liner leak are located in SX Farm. This percentage was the highest compared to other tank farms which is why SX Farm was analyzed first. The SX Farm is comprised of fifteen SSTs built 1953-1954. The tanks are arranged in rows of three tanks each, forming a cascade. Each of the SX Farm tanks has a nominal 1-million-gal storage capacity. Of the fifteen tanks in SX Farm, an assessment reported leak losses for the following tanks: 241-SX-107, 241-SX-108, 241-SX-109, 241-SX- 111, 241-SX-112, 241-SX-113, 241-SX-114 and 241-SX-115. The method used to identify leak location consisted of reviewing in-tank and ex-tank leak detection information. This provided the basic data identifying where and when the first leaks were detected. In-tank leak detection consisted of liquid level measurement that can be augmented with photographs which can provide an indication of the vertical leak location on the sidewall. Ex-tank leak detection for the leaking tanks consisted of soil radiation data from laterals and dry-wells near the tank. The in-tank and ex-tank leak detection can provide an indication of the possible leak location radially around and under the tank. Potential leak causes were determined using in-tank and ex-tank information that is not directly related to

  16. SINGLE-SHELL TANKS LEAK INTEGRITY ELEMENTS/SX FARM LEAK CAUSES AND LOCATIONS - 12127

    SciTech Connect (OSTI)

    VENETZ TJ; WASHENFELDER D; JOHNSON J; GIRARDOT C

    2012-01-25

    Washington River Protection Solutions, LLC (WRPS) developed an enhanced single-shell tank (SST) integrity project in 2009. An expert panel on SST integrity was created to provide recommendations supporting the development of the project. One primary recommendation was to expand the leak assessment reports (substitute report or LD-1) to include leak causes and locations. The recommendation has been included in the M-045-9IF Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement) as one of four targets relating to SST leak integrity. The 241-SX Farm (SX Farm) tanks with leak losses were addressed on an individual tank basis as part of LD-1. Currently, 8 out of 23 SSTs that have been reported to having a liner leak are located in SX Farm. This percentage was the highest compared to other tank farms which is why SX Farm was analyzed first. The SX Farm is comprised of fifteen SSTs built 1953-1954. The tanks are arranged in rows of three tanks each, forming a cascade. Each of the SX Farm tanks has a nominal I-million-gal storage capacity. Of the fifteen tanks in SX Farm, an assessment reported leak losses for the following tanks: 241-SX-107, 241-SX-108, 241-SX-109, 241-SX-111, 241-SX-112, 241-SX-113, 241-SX-114 and 241-SX-115. The method used to identify leak location consisted of reviewing in-tank and ex-tank leak detection information. This provided the basic data identifying where and when the first leaks were detected. In-tank leak detection consisted of liquid level measurement that can be augmented with photographs which can provide an indication of the vertical leak location on the sidewall. Ex-tank leak detection for the leaking tanks consisted of soil radiation data from laterals and drywells near the tank. The in-tank and ex-tank leak detection can provide an indication of the possible leak location radially around and under the tank. Potential leak causes were determined using in-tank and ex-tank information that is not directly related to

  17. ON THE CAUSE OF SUPRA-ARCADE DOWNFLOWS IN SOLAR FLARES

    SciTech Connect (OSTI)

    Cassak, P. A.; Shepherd, L. S.; Drake, J. F.; Gosling, J. T.; Phan, T.-D.; Shay, M. A. E-mail: lshephe1@mix.wvu.edu E-mail: Jack.Gosling@lasp.colorado.edu E-mail: shay@udel.edu

    2013-09-20

    A model of supra-arcade downflows (SADs), dark low density regions also known as tadpoles that propagate sunward during solar flares, is presented. It is argued that the regions of low density are flow channels carved by sunward-directed outflow jets from reconnection. The solar corona is stratified, so the flare site is populated by a lower density plasma than that in the underlying arcade. As the jets penetrate the arcade, they carve out regions of depleted plasma density which appear as SADs. The present interpretation differs from previous models in that reconnection is localized in space but not in time. Reconnection is continuous in time to explain why SADs are not filled in from behind as they would if they were caused by isolated descending flux tubes or the wakes behind them due to temporally bursty reconnection. Reconnection is localized in space because outflow jets in standard two-dimensional reconnection models expand in the normal (inflow) direction with distance from the reconnection site, which would not produce thin SADs as seen in observations. On the contrary, outflow jets in spatially localized three-dimensional reconnection with an out-of-plane (guide) magnetic field expand primarily in the out-of-plane direction and remain collimated in the normal direction, which is consistent with observed SADs being thin. Two-dimensional proof-of-principle simulations of reconnection with an out-of-plane (guide) magnetic field confirm the creation of SAD-like depletion regions and the necessity of density stratification. Three-dimensional simulations confirm that localized reconnection remains collimated.

  18. Mechanical failure characterization of optical components caused by laser induced damage initiated at contaminants

    SciTech Connect (OSTI)

    Faux, D. R., LLNL

    1997-12-01

    The goal of this research is to quantify by numerical techniques the effects of surface and subsurface absorbing defects on damage initiation and growth in high power laser optical components. The defects include laser absorbing spots (e.g., surface particulate contamination) and surface damage regions (e.g., micro-cracks and voids) which are present due to environmental exposure and fabrication processes. This report focuses on three sources of contamination that can cause damage to optical components: (1) Front surface particle contamination, (2) Back surface particle contamination, and (3) Subsurface particle contamination. The DYNA2D (non-linear structural mechanics) code was used to model the growth of damage in the glass substrate. The damage in the nominally transparent glass substrate as a result of front surface particle contamination was found to be dependent on the magnitude of the resultant pressure pulse applied to the particle and the initial area of contact between the particle and glass substrate. The pressures generated from a back surface particle being blown off the surface provided sufficient loading to severely damage (crack) the glass substrate. A subsurface Ceria dioxide particle showed a strong surface interaction that influenced the formation and direction of the damage (cracking) that ultimately resulted in the blow-out of the damaged material leaving a relatively clean crater in the glass. Crater shape and size was determined. Since fused silica is the most transparent, and therefore laser damage resistant, of the optical materials, it is used for the most at-risk optical elements. The present studies are for a fused silica substrate. Some oxides such as Ceria are transparent in the infrared and visible, but absorbing in the UV part of the spectrum. Because ICF lasers like NIF use frequency tripling, effects of such oxides must be included.

  19. Report of Flood, Oil Sheen, and fish Kill Incidents on East Fork Poplar Creek at the Oak Ridge Y-12 Plant

    SciTech Connect (OSTI)

    Skaggs, B.E.

    1997-09-01

    Water quality and plant opemtion irriiormation provided by the Y-12 Plant strongly suggest that a dechlorinating agent, applied to the raw water released below the North-South Pipes was responsible for the toxicity resulting in the fish kill of July 24. Dissolved oxygen (DO) measurements in upper EFPC indicai e that low oxygen levels (3-5 ppm) occurred for a period of up to 30 min. This slug of low DO water traveling down EFPC to the lake could easily explain the massive fish kill and the resulting observations. Dissolved oxygen levels of 5.2 ppm or lower are documented as causing problems for warmwater fish species (Heath 1995). The presence of other stressors, including a range of petrochemicals, tends to lower resistance to low oxygen conditions. Given the sequence of events in upper EFPC in the few days prior to July 24, where extremely high flows were followed by inputs of a wide range of low concentrations of oils, the sensitivity to low DO conditions might be heightened. The possible toxic impact of ::he oils and other contaminants reaching EFPC as a result of the heavy rainfidl on July 22 doesn't appear significant enough to be the sole cause of the kill on July 24. Even during the height of the kill, a large school of fish remained immediately downstream of the North-South Pipes. If the toxicity of waters flowing through this outlet were the primary cause of the kill, then it would be expected that this school of fish would not have been present immediately below the pipes. Any impact of waters entering from other sources, such as pumping of basements WOUIC1 have produced a staggered pattern of mortality, with fishing dying in different localities at different times and rates. Further, it would be expected that the morta.lhy observed would have continued over several days at least, as more resistant individuals succumbed slowly to the toxic exposure. This would have provided freshly dead or dying fish for the surveys of July 25 and 28. In previous fish

  20. Effects of Increased Upward Flux of Saline Water Caused by CO2 Storage or Other Factors

    SciTech Connect (OSTI)

    Murdoch, Lawrence; Xie, Shuang; Falta, Ronald W.; Yonkofski, Catherine MR

    2015-08-01

    likely be minor if the upward flux was smaller than a few tenths of the magnitude of recharge, according to the 2D analyses. The 3D analyses also show that upward flux could occur without a significant increase in the risk categories. The major contribution of this work is that it shows how a large increase in diffuse upward flux from a basin could cause significant problems, but a small increase in upward flux may occur without significantly affecting risks to the shallow freshwater flow system. This heightens the importance of understanding interactions between shallow and deep hydrologic systems when characterizing CO2 storage projects.

  1. Released: September, 2008

    U.S. Energy Information Administration (EIA) Indexed Site

    Consumption (trillion Btu)" ,"Total ","Space Heat- ing","Cool- ing","Venti- lation","Water Heat- ing","Light- ing","Cook- ing","Refrig- eration","Office Equip- ment","Com-...

  2. Revised: December, 2008

    U.S. Energy Information Administration (EIA) Indexed Site

    (thousand Btusquare foot) " ,"Total ","Space Heat- ing","Cool- ing","Venti- lation","Water Heat- ing","Light- ing","Cook- ing","Refrig- eration","Office Equip- ment","Com-...

  3. --No Title--

    Gasoline and Diesel Fuel Update (EIA)

    End Use for Non-Mall Buildings, 2003 Total Major Fuel Consumption (trillion Btu) Total Space Heat- ing Cool- ing Venti- lation Water Heat- ing Light- ing Cook- ing Refrig- eration...

  4. --No Title--

    Gasoline and Diesel Fuel Update (EIA)

    Energy Intensity (kWhsquare foot) Total Space Heat- ing Cool- ing Venti- lation Water Heat- ing Light- ing Cook- ing Refrig- eration Office Equip- ment Com- puters Other...

  5. --No Title--

    Gasoline and Diesel Fuel Update (EIA)

    Electricity Consumption (billion kWh) Total Space Heat- ing Cool- ing Venti- lation Water Heat- ing Light- ing Cook- ing Refrig- eration Office Equip- ment Com- puters Other...

  6. Total Space Heat-

    Gasoline and Diesel Fuel Update (EIA)

    Survey: Energy End-Use Consumption Tables Total Space Heat- ing Cool- ing Venti- lation Water Heat- ing Light- ing Cook- ing Refrig- eration Office Equip- ment Com- puters Other...

  7. CAUSE OF A MULTI-SPECIES RADIOIODINE PLUME THAT IS INCREASING IN CONCENTRATION

    SciTech Connect (OSTI)

    Kaplan, D.

    2010-09-30

    Field and laboratory studies were carried out to understand the cause for steady increases in {sup 129}I concentrations emanating from radiological seepage basins located on the Savannah River Site. The basins were closed in 1988 by adding limestone and blast furnace slag and then capping with a RCRA low permeability engineered cover. Groundwater {sup 129}I concentrations in a well near the seepage basin in 1993 were 200 pCi L{sup -1} and are presently between 400 and 1000 pCi L{sup -1}. Iodine speciation in the plume was not uniform. Near the source, the iodine was comprised of 86% iodide, 2% iodate, and 12% organo-iodine (total activity = 178 pCi L{sup -1}). Whereas, groundwater iodine speciation 365 m down stream (25 m up stream from a wetland) was 0% iodide, 93% iodate, and 7% organo iodine. Batch desorption studies demonstrated that high concentrations of {sup 129}I could be incrementally desorbed from an archived seepage basin sediment sample by raising the pH. Batch sorption studies showed that iodate, IO{sub 3}{sup -}, sorbed more strongly than iodide, I{sup -}, to a subsurface clayey sediment, but equally well as iodide to a subsurface sandy sediment and a wetland sediment. Placing an organic-rich wetland sediment, but not nearby mineral sediments, under reducing (or microaerobic) conditions resulted in a large decrease in iodide K{sub d} values (from 73 to 10 mL g{sup -1}) and iodate K{sub d} values (from 80 to 7 mL g{sup -1}). Between pH and reduction-oxidation potential, it appears that pH seems to have a stronger influence on iodide and iodate sorption to mineral sediment. This may not be true for sediments containing higher concentrations of organic matter, such as the 7.6% organic matter sediment used in this study. First order calculations based on desorption studies with seepage basin sediments indicate that the modest increase of 0.7 pH units detected in the study site groundwater over the last 17 years since closure of the seepage basin may be

  8. Polycyclic aromatic hydrocarbons (PAHs): a possible cause of lung cancer mortality among nickel/copper smelter and refinery workers

    SciTech Connect (OSTI)

    Verma, D.K.; Julian, J.A.; Roberts, R.S.; Muir, D.C.; Jadon, N.; Shaw, D.S. )

    1992-05-01

    A retrospective industrial hygiene investigation was undertaken to explain the cause of a statistically significant excess lung cancer mortality observed in a subset of a large cohort of nickel workers involved in mining, smelting, and refining of nickel and copper in Ontario. The focus of this paper is to demonstrate how an industrial hygiene follow-up assessment of an epidemiologic finding can help to identify a likely cause. Polycyclic aromatic hydrocarbons (PAHs) alone or in association with particulate and gaseous contaminants (e.g., SO2) were likely the causative agents of the excess lung cancer observed among the lead welders, cranemen, and arc furnace workers of the copper refinery.

  9. Health risk from earthquake caused releases of UF{sub 6} at the Paducah Gaseous Diffusion Plant

    SciTech Connect (OSTI)

    Brown, N.W; Lu, S.; Chen, J.C.; Roehnelt, R.; Lombardi, D.

    1998-05-01

    The health risk to the public and workers from potential exposure to the toxic materials from earthquake caused releases of uranium hexafluoride from the Paducah gaseous Diffusion Plant are evaluated. The results of the study show that the health risk from earthquake caused releases is small, and probably less than risks associated with the transportation of hydrogen fluoride and other similar chemicals used by industry. The probability of more than 30 people experiencing health consequences (injuries) from earthquake damage is less than 4xlO{sup 4}/yr.

  10. /ital Q/-modulation and four-wave mixing effects caused by RSA materials in a laser cavity

    SciTech Connect (OSTI)

    Zhang Tao; Yao Jianquan

    1989-04-01

    By making use of the density-matrix method, we give a unified explanation of /ital Q/-modulation and four-wave mixing effects caused by resonant saturable absorption (RSA) materials in a laser cavity. The underlying physical mechanism of the effects is expressed clearly. The theoretical calculation results agree very well with the experimental data.

  11. Land subsidence caused by withdrawal of oil and gas in the Gulf coastal plain - The Houston, Texas, case history

    SciTech Connect (OSTI)

    Holzer, T.L. )

    1990-09-01

    The extensive network of geodetic leveling lines in the Houston-Galveston, Texas, area, where at least 110 oil and gas fields have been developed, provides the most comprehensive opportunity in the Gulf Coast to search for the occurrence of land subsidence caused by withdrawal of oil and gas. Although the evaluation is complicated by regional subsidence caused by a decline of ground-water level in aquifers beneath the area, subsidence caused by oil and gas withdrawal can be examined by searching for local increases of subsidence at oil and gas fields crossed by leveling lines. Twenty-nine fields are crossed by lines with repeated leveling surveys. Subsidence profiles across these fields indicate local increases of subsidence at six fields-Alco-Mag, Chocolate Bayou, Goose Creek, Hastings, Mykawa, and South Houston. Although ground-water withdrawal is undoubtedly the most important factor contributing to the total subsidence at each field, oil and gas withdrawal may be partly responsible for the local increases. Except for Chocolate Bayou, the volume of petroleum production at each field was sufficient to account for the increase. The volume of petroleum production, however, in general is not a reliable index for predicting the local increase because land within many fields with significant production did not show local increases of subsidence. With the exception of the 1 m subsidence caused by petroleum withdrawal at Goose Creek (1917-1925), local increases of subsidence were less than 0.3 m.

  12. Experimental Investigation of the Root Cause Mechanism and Effectiveness of Mitigating Actions for Axial Offset Anomaly in Pressurized Water Reactors

    SciTech Connect (OSTI)

    Said Abdel-Khalik

    2005-07-02

    Axial offset anomaly (AOA) in pressurized water reactors refers to the presence of a significantly larger measured negative axial offset deviation than predicted by core design calculations. The neutron flux depression in the upper half of high-power rods experiencing significant subcooled boiling is believed to be caused by the concentration of boron species within the crud layer formed on the cladding surface. Recent investigations of the root-cause mechanism for AOA [1,2] suggest that boron build-up on the fuel is caused by precipitation of lithium metaborate (LiBO2) within the crud in regions of subcooled boiling. Indirect evidence in support of this hypothesis was inferred from operating experience at Callaway, where lithium return and hide-out were, respectively, observed following power reductions and power increases when AOA was present. However, direct evidence of lithium metaborate precipitation within the crud has, heretofore, not been shown because of its retrograde solubility. To this end, this investigation has been undertaken in order to directly verify or refute the proposed root-cause mechanism of AOA, and examine the effectiveness of possible mitigating actions to limit its impact in high power PWR cores.

  13. Adequacy of Power-to-Mass Scaling in Simulating PWR Incident Transient for Reduced-Height, Reduced-Pressure and Full-Height, Full-Pressure Integral System Test Facilities

    SciTech Connect (OSTI)

    Liu, T.-J.; Lee, C.-H

    2004-03-15

    A complete scheme of scaling methods to design the reduced-height, reduced-pressure (RHRP) Institute of Nuclear Energy Research Integral System Test (IIST) facility and to specify test conditions for incident simulation was developed. In order to preserve core decay power history and coolant mass inventory during a transient, a unique power-to-mass scaling method is proposed and utilized for RHRP and full-height, full-pressure (FHFP) systems. To validate the current scaling method, three counterpart tests done at the IIST facility are compared with the FHFP tests in small-break loss-of-coolant, station blackout, and loss-of-feedwater accidents performed at the Large-Scale Test Facility (LSTF) and the BETHSY test facility. Although differences appeared in design, scaling, and operation conditions among the IIST, LSTF, and BETHSY test facilities, the important physical phenomena shown in the facilities are almost the same. The physics involved in incident transient phenomena are well measured and modeled by showing the common thermal-hydraulic behavior of key parameters and the general consistency of chronological events. The results also confirm the adequacy of power-to-mass scaling methodology.

  14. Analysis of single-event upset of magnetic tunnel junction used in spintronic circuits caused by radiation-induced current

    SciTech Connect (OSTI)

    Sakimura, N.; Nebashi, R.; Sugibayashi, T.; Natsui, M.; Hanyu, T.; Ohno, H.

    2014-05-07

    This paper describes the possibility of a switching upset of a magnetic tunnel junction (MTJ) caused by a terrestrial radiation-induced single-event-upset (SEU) current in spintronic integrated circuits. The current waveforms were simulated by using a 3-D device simulator in a basic circuit including MTJs designed using 90-nm CMOS parameters and design rules. The waveforms have a 400 -μA peak and a 200-ps elapsed time when neutron particles with a linear energy transfer value of 14 MeV cm{sup 2}/mg enter the silicon surface. The authors also found that the SEU current may cause soft errors with a probability of more than 10{sup −12} per event, which was obtained by approximate solution of the ordinary differential equation of switching probability when the intrinsic critical current (I{sub C0}) became less than 30 μA.

  15. Common cause failure analysis of the rodded scram system of the Arkansas Nuclear One-Unit 1 Plant

    SciTech Connect (OSTI)

    Montague, D.F.; Campbell, D.J.; Flanagan, G.F.

    1986-10-01

    This study demonstrates the use of a formal method for common cause failure analysis in a reliability analysis of the Arkansas Nuclear One - Unit 1 rodded scram system. The scram system failure of interest is loss of capability of the system to shut the reactor down when required. The results of this analysis support the ATWS program sponsored by the US Nuclear Regulatory Commission. The methods used in this analysis support the NRC's Risk Methods Integration and Evaluation Program (RMIEP).

  16. Epizootic ulcerative syndrome caused by Aphanomyces invadans in captive bullseye snakehead Channa marulius collected from south Florida, USA

    SciTech Connect (OSTI)

    Saylor, Ryan; Miller, Debra; Vandersea, Mark; Bevelhimer, Mark S; Schofield, Pamela; Bennett, Wayne

    2010-02-01

    Epizootic ulcerative syndrome (EUS) caused by the oomycete Aphanomyces invadans is an invasive, opportunistic disease of both freshwater and estuarine fishes. Originally documented as the cause of mycotic granulomatosis of ornamental fishes in Japan and as the cause of EUS of fishes in southeast Asia and Australia, this pathogen is also present in estuaries and freshwater bodies of the Atlantic and gulf coasts of the USA. We describe a mass mortality event of 343 captive juvenile bullseye snakehead Channa marulius collected from freshwater canals in Miami-Dade County, Florida. Clinical signs appeared within the first 2 d of captivity and included petechiae, ulceration, erratic swimming, and inappetence. Histological examination revealed hyphae invading from the skin lesions deep into the musculature and internal organs. Species identification was confirmed using a species-specific PCR assay. Despite therapeutic attempts, 100% mortality occurred. This represents the first documented case of EUS in bullseye snakehead fish collected from waters in the USA. Future investigation of the distribution and prevalence of A. invadans within the bullseye snakehead range in south Florida may give insight into this pathogen-host system.

  17. Divergent predictions of carbon storage between two global land models: attribution of the causes through traceability analysis

    SciTech Connect (OSTI)

    Rafique, Rashid; Xia, Jianyang; Hararuk, Oleksandra; Asrar, Ghassem R.; Wang, Yingping; Luo, Yiqi

    2015-08-27

    Representations of the terrestrial carbon cycle in land models are becoming increasingly complex. It is crucial to develop approaches for critical assessment of the complex model properties in order to understand key factors contributing to models’ performance. In this study, we applied a traceability analysis, which decomposes carbon cycle models into traceable components, to two global land models (CABLE and CLM-CASA’) to diagnose the causes of their differences in simulating ecosystem carbon storage capacity. Driven with similar forcing data, the CLM-CASA’ model predicted ~31% larger carbon storage capacity than the CABLE model. Since ecosystem carbon storage capacity is a product of net primary productivity (NPP) and ecosystem residence time (τE), the predicted difference in the storage capacity between the two models results from differences in either NPP or τE or both. Our analysis showed that CLM-CASA’ simulated 37% higher NPP than CABLE due to higher rates of carboxylation (Vcmax) in CLM-CASA’. On the other hand, τE , which was a function the baseline carbon residence time (τ´E) and environmental effect on carbon residence time, was on average 11 years longer in CABLE than CLM-CASA’. The difference in τE was mainly found to be caused by longer τ´E in CABLE than CLM-CASA’. This difference in τE was mainly caused by longer τ´E of woody biomass (23 vs. 14 years in CLM-CASA’) and higher proportion of NPP allocated to woody biomass (23% vs. 16%). Differences in environmental effects on carbon residence times had smaller influences on differences in ecosystem carbon storage capacities compared to differences in NPP and τ´E. Overall; the traceability analysis is an effective method for identifying sources of variations between the two models.

  18. Causes and solutions for cracking of coextruded and weld overlay floor tubes in black liquor recovery boilers

    SciTech Connect (OSTI)

    Keiser, J.R.; Taljat, B.; Wang, X.L.

    1998-09-01

    Cracking of coextruded, black liquor recovery boiler floor tubes is both a safety and an economic issue to mill operators. In an effort to determine the cause of the cracking and to identify a solution, extensive studies, described in this and three accompanying papers, are being conducted. In this paper, results of studies to characterize both the cracking and the chemical and thermal environment are reported. Based on the results described in this series of papers, a possible mechanism is presented and means to lessen the likelihood of cracking or to totally avoid cracking of floor tubes are offered.

  19. Cholesterol accumulation in Niemann Pick type C (NPC) model cells causes a shift in APP localization to lipid rafts

    SciTech Connect (OSTI)

    Kosicek, Marko; Malnar, Martina; Goate, Alison; Hecimovic, Silva

    2010-03-12

    It has been suggested that cholesterol may modulate amyloid-{beta} (A{beta}) formation, a causative factor of Alzheimer's disease (AD), by regulating distribution of the three key proteins in the pathogenesis of AD ({beta}-amyloid precursor protein (APP), {beta}-secretase (BACE1) and/or presenilin 1 (PS1)) within lipid rafts. In this work we tested whether cholesterol accumulation upon NPC1 dysfunction, which causes Niemann Pick type C disease (NPC), causes increased partitioning of APP into lipid rafts leading to increased CTF/A{beta} formation in these cholesterol-rich membrane microdomains. To test this we used CHO NPC1{sup -/-} cells (NPC cells) and parental CHOwt cells. By sucrose density gradient centrifugation we observed a shift in fl-APP/CTF compartmentalization into lipid raft fractions upon cholesterol accumulation in NPC vs. wt cells. Furthermore, {gamma}-secretase inhibitor treatment significantly increased fl-APP/CTF distribution in raft fractions in NPC vs. wt cells, suggesting that upon cholesterol accumulation in NPC1-null cells increased formation of APP-CTF and its increased processing towards A{beta} occurs in lipid rafts. Our results support that cholesterol overload, such as in NPC disease, leads to increased partitioning of APP/CTF into lipid rafts resulting in increased amyloidogenic processing of APP in these cholesterol-rich membranes. This work adds to the mechanism of the cholesterol-effect on APP processing and the pathogenesis of Alzheimer's disease and supports the role of lipid rafts in these processes.

  20. Prevention of Gynecomastia and Breast Pain Caused by Androgen Deprivation Therapy in Prostate Cancer: Tamoxifen or Radiotherapy?

    SciTech Connect (OSTI)

    Arruda Viani, Gustavo; Bernardes da Silva, Lucas Godoi; Stefano, Eduardo Jose

    2012-07-15

    Purpose: To determine, in a meta-analysis, whether gynecomastia and breast pain rates in men with prostate cancer treated with androgen deprivation therapy (ADT) are reduced if treated with prophylactic radiotherapy (RT) or tamoxifen (TMX). Methods and Materials: The MEDLINE, EMBASE, CANCERLIT, and Cochrane Library databases, as well as proceedings of annual meetings, were systematically searched to identify randomized, controlled studies comparing RT or TMX with observation for men with prostate cancer using ADT. Results: Six RCTs (three RT trials and three TMX trials, N = 777 patients total) were identified that met the study criteria. Pooled results from these RCTs comparing RT vs. observation showed a significant reduction in the incidence of gynecomastia and breast pain rates in patients treated with RT (odds ratio [OR] = 0.21, 95% confidence interval [CI] = 0.12-0.37, p < 0.0001, and OR = 0.34, 95% CI 0.20-0.57, p < 0.0001, respectively). Use of RT resulted in an absolute risk reduction (ARR) of 29.4% and 19.9%, with a number needed to treat (NNT) of 3.4 and 5 to avoid one case of gynecomastia and breast pain, respectively. Pooled results from trials comparing TMX vs. observation showed a statistical benefit for breast pain and gynecomastia in favor of TMX arms (OR = 0.04, 95% CI = 0.02-0.08, p < 0.0001 and OR = 0.07, 95% CI = 0.0-0.14, p < 0.00001). TMX resulted in an ARR = 64.1% and 47.6%, with an NNT of 1.56 and 2.1 to avoid one case of gynecomastia and breast pain, respectively. Considering adverse effects, TMX was 6 times more adverse effects than RT. Conclusions: Our data have shown that both TMX and RT prevented gynecomastia and breast pain in patients with prostate cancer receiving ADT for prostate cancer. Although TMX was two times more effective in preventing gynecomastia, RT should represent an effective and safe treatment option, to take into account mainly in patients with cardiovascular risk factors or thrombotic diathesis.

  1. Phase matching of high order harmonic generation using dynamic phase modulation caused by a non-collinear modulation pulse

    DOE Patents [OSTI]

    Cohen, Oren; Kapteyn, Henry C.; Mumane, Margaret M.

    2010-02-16

    Phase matching high harmonic generation (HHG) uses a single, long duration non-collinear modulating pulse intersecting the driving pulse. A femtosecond driving pulse is focused into an HHG medium (such as a noble gas) to cause high-harmonic generation (HHG), for example in the X-ray region of the spectrum, via electrons separating from and recombining with gas atoms. A non-collinear pulse intersects the driving pulse within the gas, and modulates the field seen by the electrons while separated from their atoms. The modulating pulse is low power and long duration, and its frequency and amplitude is chosen to improve HHG phase matching by increasing the areas of constructive interference between the driving pulse and the HHG, relative to the areas of destructive interference.

  2. Simulation of the signals of a pancake-type transducer caused by a plane defect of arbitrary form

    SciTech Connect (OSTI)

    Beda, P.I.; Putnikov, Yu.G.

    1994-10-01

    Redistribution of eddy currents caused by a defect is represented by a multitude of the fine circular contours located in that portion of the area of significant eddy currents associated with the defect. The current in the contours of the model {Delta}I{sub km} is expressed in terms of the primary current of each defect I{sub km} and the function of influence of the defect calculated with use of equivalent electrical circuits. The discretely distributed density of eddy currents is considered as an external current in the Helmholtz equation by solution of which an equation is obtained for the eddy current transducer voltage introduced by the defect. The method presented for calculation of eddy current transducer signals from a plane defect may be used in many cases for any type of pancake, solenoid, submersible, screen, and other transducers and for any form of object of inspection when the rule of spatial distribution of the eddy current density is known.

  3. Cancer incidence in the Love Canal area

    SciTech Connect (OSTI)

    Janerich, D.T.; Burnett, W.S.; Feck, G.; Hoff, M.; Nasca, P.; Polednak, A.P.; Greenwald, P.; Vianna, N.

    1981-06-01

    Data from the New York Cancer Registry show no evidence for higher cancer rates associated with residence near the Love Canal toxic waste burial site in comparison with the entire state outside of New York City. Rates of liver cancer, lymphoma, and leukemia, which were selected for special attention, were not consistently elevated. Among the other cancers studied, a higher rate was noted only for respiratory cancer, but it was not consistent across age groups and appeared to be related to a high rate for the entire city of Niagara Falls. There was no evidence that the lung cancer rate was associated with the toxic wastes buried at the dump site.

  4. Chemical incident economic impact analysis methodology. (Technical...

    Office of Scientific and Technical Information (OSTI)

    Close Cite: Bibtex Format Close 0 pages in this document matching the terms "" Search For Terms: Enter terms in the toolbar above to search the full text of this document for ...

  5. EUV mirror based absolute incident flux detector

    DOE Patents [OSTI]

    Berger, Kurt W.

    2004-03-23

    A device for the in-situ monitoring of EUV radiation flux includes an integrated reflective multilayer stack. This device operates on the principle that a finite amount of in-band EUV radiation is transmitted through the entire multilayer stack. This device offers improvements over existing vacuum photo-detector devices since its calibration does not change with surface contamination.

  6. Chapter_11_Incidents_of_Security_Concern

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... compromise, the extent of dissemination (e.g., number of individuals and their citizenship; global disclosure via cyber media; open source publication; etc.) * If a DA was ...

  7. Researchers correlate incidences of rheumatoid arthritis and...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    A coronal mass ejection hurling plasma from the sun (Photo by NASA) A coronal mass ejection hurling plasma from the sun What began as a chat between husband and wife has ...

  8. Radioactive Materials Transportation and Incident Response

    Broader source: Energy.gov [DOE]

    This booklet was written to answer questions most frequently asked by fire fighters, law enforcement officers, and emergency medical services personnel. The booklet is not intended as a substitute...

  9. Incidents of chemical reactions in cell equipment

    SciTech Connect (OSTI)

    Baldwin, N.M.; Barlow, C.R.

    1991-12-31

    Strongly exothermic reactions can occur between equipment structural components and process gases under certain accident conditions in the diffusion enrichment cascades. This paper describes the conditions required for initiation of these reactions, and describes the range of such reactions experienced over nearly 50 years of equipment operation in the US uranium enrichment program. Factors are cited which can promote or limit the destructive extent of these reactions, and process operations are described which are designed to control the reactions to minimize equipment damage, downtime, and the possibility of material releases.

  10. JC3 Incident Reporting | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    in their Cyber Security Program Plans (CSPPs) or similar documents for classified systems. ... Classified Spillage: Transfer of classified or sensitive information to unaccredited or ...

  11. Computerized Accident Incident Reporting System | Department...

    Broader source: Energy.gov (indexed) [DOE]

    CAIRS References and Resources The Office of Environment, Health, Safety and Security (AU) ... DOE Summary Statistics - The CAIRS database is constantly being updated or revised, The ...

  12. VAST Challenge 2014: The Kronos Incident

    SciTech Connect (OSTI)

    Whiting, Mark A.; Cook, Kristin A.; Grinstein, Georges; Liggett, Kristen; Cooper, Michael J.; Fallon, John; Morin, Marc P.

    2014-10-31

    The 2014 IEEE Visual Analytics Science and Technology (VAST) Challenge presented researchers with a single fictitious scenario: the disappearance of staff members of the GASTech oil and gas company on location on the island of Kronos. A group named the Protectors of Kronos (POK) was the prime suspect in the disappearance. Three mini-challenges and a grand challenge were offered. Mini-challenge 1 included multiple types of text data for participants to provide a timeline of key events and characterize the POK, mini-challenge 2 focused on individuals’ movement and financial data for participants to provide patterns of daily life, and mini-challenge 3 featured real-time streaming social media and emergency service data for participants to provide hostage and kidnapper information. The grand challenge asked the participants to integrate results and generate a synopsis of events. The VAST Challenge received 73 submissions from 13 countries

  13. Evaluation of the carbon content of aerosols from the burn- ing of biomass in the Brazilian Amazon using thermal, op- tical and thermal-optical analysis methods

    SciTech Connect (OSTI)

    Soto-Garcia, Lydia L.; Andreae, Meinrat O.; Andreae, Tracey W.; taxo, Paulo Ar-; Maenhaut, Willy; Kirchstetter, Thomas; Novakov, T.; Chow, Judith C.; Mayol-Bracero, Olga L.

    2011-06-03

    Aerosol samples were collected at a pasture site in the Amazon Basin as part of the project LBA-SMOCC-2002 (Large-Scale Biosphere-Atmosphere Experiment in Amazonia - Smoke Aerosols, Clouds, Rainfall and Climate: Aerosols from Biomass Burning Perturb Global and Regional Climate). Sampling was conducted during the late dry season, when the aerosol composition was dominated by biomass burning emissions, especially in the submicron fraction. A 13-stage Dekati low-pressure impactor (DLPI) was used to collect particles with nominal aerodynamic diameters (D{sub p}) ranging from 0.03 to 0.10 m. Gravimetric analyses of the DLPI substrates and filters were performed to obtain aerosol mass concentrations. The concentrations of total, apparent elemental, and organic carbon (TC, EC{sub a}, and OC) were determined using thermal and thermal-optical analysis (TOA) methods. A light transmission method (LTM) was used to determine the concentration of equivalent black carbon (BC{sub e}) or the absorbing fraction at 880 nm for the size-resolved samples. During the dry period, due to the pervasive presence of fires in the region upwind of the sampling site, concentrations of fine aerosols (D{sub p} < 2.5 {mu}m: average 59.8 {mu}g m{sup -3}) were higher than coarse aerosols (D{sub p} > 2.5 {mu}m: 4.1 {mu}g m{sup -3}). Carbonaceous matter, estimated as the sum of the particulate organic matter (i.e., OC x 1.8) plus BC{sub e}, comprised more than 90% to the total aerosol mass. Concentrations of EC{sub a} (estimated by thermal analysis with a correction for charring) and BCe (estimated by LTM) averaged 5.2 {+-} 1.3 and 3.1 {+-} 0.8 {mu}g m{sup -3}, respectively. The determination of EC was improved by extracting water-soluble organic material from the samples, which reduced the average light absorption {angstrom} exponent of particles in the size range of 0.1 to 1.0 {mu}m from > 2.0 to approximately 1.2. The size-resolved BC{sub e} measured by the LTM showed a clear maximum between 0.4 and 0.6 m in diameter. The concentrations of OC and BC{sub e} varied diurnally during the dry period, and this variation is related to diurnal changes in boundary layer thickness and in fire frequency.

  14. Grazing incidence angle based sensing approach integrated with fiber-optic Fourier transform infrared (FO-FTIR) spectroscopy for remote and label-free detection of medical device contaminations

    SciTech Connect (OSTI)

    Hassan, Moinuddin Ilev, Ilko

    2014-10-15

    Contamination of medical devices has become a critical and prevalent public health safety concern since medical devices are being increasingly used in clinical practices for diagnostics, therapeutics and medical implants. The development of effective sensing methods for real-time detection of pathogenic contamination is needed to prevent and reduce the spread of infections to patients and the healthcare community. In this study, a hollow-core fiber-optic Fourier transform infrared spectroscopy methodology employing a grazing incidence angle based sensing approach (FO-FTIR-GIA) was developed for detection of various biochemical contaminants on medical device surfaces. We demonstrated the sensitivity of FO-FTIR-GIA sensing approach for non-contact and label-free detection of contaminants such as lipopolysaccharide from various surface materials relevant to medical device. The proposed sensing system can detect at a minimum loading concentration of approximately 0.7 ?g/cm{sup 2}. The FO-FTIR-GIA has the potential for the detection of unwanted pathogen in real time.

  15. Failure and Redemption of Multifilter Rotating Shadowband Radiometer (MFRSR)/Normal Incidence Multifilter Radiometer (NIMFR) Cloud Screening: Contrasting Algorithm Performance at Atmospheric Radiation Measurement (ARM) North Slope of Alaska (NSA) and Southern Great Plains (SGP) Sites

    SciTech Connect (OSTI)

    Kassianov, Evgueni I.; Flynn, Connor J.; Koontz, Annette S.; Sivaraman, Chitra; Barnard, James C.

    2013-09-11

    Well-known cloud-screening algorithms, which are designed to remove cloud-contaminated aerosol optical depths (AOD) from AOD measurements, have shown great performance at many middle-to-low latitude sites around the world. However, they may occasionally fail under challenging observational conditions, such as when the sun is low (near the horizon) or when optically thin clouds with small spatial inhomogeneity occur. Such conditions have been observed quite frequently at the high-latitude Atmospheric Radiation Measurement (ARM) North Slope of Alaska (NSA) sites. A slightly modified cloud-screening version of the standard algorithm is proposed here with a focus on the ARM-supported Multifilter Rotating Shadowband Radiometer (MFRSR) and Normal Incidence Multifilter Radiometer (NIMFR) data. The modified version uses approximately the same techniques as the standard algorithm, but it additionally examines the magnitude of the slant-path line of sight transmittance and eliminates points when the observed magnitude is below a specified threshold. Substantial improvement of the multi-year (1999-2012) aerosol product (AOD and its Angstrom exponent) is shown for the NSA sites when the modified version is applied. Moreover, this version reproduces the AOD product at the ARM Southern Great Plains (SGP) site, which was originally generated by the standard cloud-screening algorithms. The proposed minor modification is easy to implement and its application to existing and future cloud-screening algorithms can be particularly beneficial for challenging observational conditions.

  16. Investigation of the Cause of Low Blister Threshold Temperatures in the RERTR-12 and AFIP-4 Experiments

    SciTech Connect (OSTI)

    Mitchell K Meyer

    2012-06-01

    Blister–threshold testing of fuel plates is a standard method through which the safety margin for operation of plate-type in research and test reactors is assessed. The blister-threshold temperature is indicative of the ability of fuel to operate at high temperatures for short periods of time (transient conditions) without failure. This method of testing was applied to the newly developed U-Mo monolithic fuel system. Blister annealing studies on the U-Mo monolithic fuel plates began in 2007, with the Reduced Enrichment for Research and Test Reactors (RERTR)-6 experiment, and they have continued as the U-Mo fuel system has evolved through the research and development process. Blister anneal threshold temperatures from early irradiation experiments (RERTR-6 through RERTR-10) ranged from 400 to 500°C. These temperatures were projected to be acceptable for NRC-licensed research reactors and the high-power Advanced Test Reactor (ATR) and the High Flux Isotope Reactor (HFIR) based on current safety-analysis reports (SARs). Initial blister testing results from the RERTR-12 experiment capsules X1 and X2 showed a decrease in the blister-threshold temperatures. Blister threshold temperatures from this experiment ranged from 300 to 400°C. Selected plates from the AFIP-4 experiment, which was fabricated using a process similar to that used to fabricate the RERTR-12 experiment, also underwent blister testing to determine whether results would be similar. The measured blister-threshold temperatures from the AFIP-4 plates fell within the same blister-threshold temperature range measured in the RERTR-12 plates. Investigation of the cause of this decrease in bister threshold temperature is being conducted under the guidance of Idaho National Laboratory PLN-4155, “Analysis of Low Blister Threshold Temperatures in the RERTR-12 and AFIP-4 Experiments,” and is driven by hypotheses. The main focus of the investigation is in the following areas: 1. Fabrication variables 2. Pre

  17. Absence of correlation between Sry polymorphisms and XY sex reversal caused by the M.m. domesticus Y chromosome

    SciTech Connect (OSTI)

    Carlisle, C.; Nagamine, C.M. [Vanderbilt Univ., School of Medicine, Nashville, TN (United States)] [Vanderbilt Univ., School of Medicine, Nashville, TN (United States); Winkinig, H.; Weichenhan, D. [Medizinische Universitaet Zu Luebeck (Germany)] [Medizinische Universitaet Zu Luebeck (Germany)

    1996-04-01

    Mus musculus domesticus Y chromosomes (Y{sup DOM} Chrs) vary in their ability to induce testes in the strain C57BL/6J. In severe cases, XY females develop (XY{sup DOM} sex reversal). To identify the molecular basis for the sex reversal, a 2.7-kb region of Sry, the testis-determining gene, was sequenced from Y{sup DOM} Chrs linked to normal testis determination, transient sex reversal, and severe sex reversal. Four mutations were identified. However, no correlation exists between these mutations and severity of XY{sup DOM} sex reversal. RT-PCR identified Sry transcripts in XY{sup DOM} sex-reversed fetal gonads at 11 d.p.c., the age when Sry is hypothesized to function. In addition, no correlation exists between XY{sup DOM} sex reversal and copy numbers of pSx1, a Y-repetitive sequence whose deletion is linked to XY sex reversal. We conclude that SRY protein variants, blockade of Sry transcription, and deletion of pSx1 sequences are not the underlying causes of XY{sup DOM} sex reversal. 63 refs., 6 figs., 6 tabs.

  18. Effect of Water Radiolysis Caused by Dispersed Radionuclides on Oxidative Dissolution of Spent Fuel in a Final Repository

    SciTech Connect (OSTI)

    Liu Jinsong; Neretnieks, Ivars

    2001-08-15

    When released out of a canister, the radionuclides originally incorporated in the spent fuel can still deposit radiation energy (even more efficiently) into the pore water, cause water radiolysis, and produce oxidants in the buffering material. This phenomenon is termed secondary water radiolysis. The oxidants thus produced can possibly diffuse back to oxidize the spent fuel and to increase the oxidative dissolution rate of the fuel.The effect of the secondary water radiolysis has been identified and preliminarily addressed by a mass-balance model. To explore whether the effect is significant on spent-fuel dissolution, the upper-boundary limit of the effect has been set up by considering a scenario that is very unlikely to occur. Several extreme assumptions have been made: First, the canister fails completely 10{sup 3} yr after deposition; second, the spent fuel is oxidized instantaneously; and third, the radionuclides considered are those that dominantly contribute to radiolysis between 10{sup 3} to 10{sup 5} yr. With these assumptions, the spent-fuel dissolution rate can be increased dramatically if 10% or more of the oxidants produced by the secondary water radiolysis diffuse back to oxidize the spent fuel. It thus indicates that the effect of the secondary water radiolysis could be significant with some extreme assumptions. With more realistic assumptions, the effect could possibly become minimal. The subject is worth further investigation.

  19. Brine flow up a borehole caused by pressure perturbation from CO2 storage: Static and dynamic evaluations

    SciTech Connect (OSTI)

    Birkholzer, J.T.; Nicot, J.-P.; Oldenburg, C.M.; Zhou, Q.; Kraemer, S.; Bandilla, K.W.

    2011-05-01

    Industrial-scale storage of CO{sub 2} in saline sedimentary basins will cause zones of elevated pressure, larger than the CO{sub 2} plume itself. If permeable conduits (e.g., leaking wells) exist between the injection reservoir and overlying shallow aquifers, brine could be pushed upwards along these conduits and mix with groundwater resources. This paper discusses the potential for such brine leakage to occur in temperature- and salinity-stratified systems. Using static mass-balance calculations as well as dynamic well flow simulations, we evaluate the minimum reservoir pressure that would generate continuous migration of brine up a leaking wellbore into a freshwater aquifer. Since the brine invading the well is denser than the initial fluid in the wellbore, continuous flow only occurs if the pressure perturbation in the reservoir is large enough to overcome the increased fluid column weight after full invasion of brine into the well. If the threshold pressure is exceeded, brine flow rates are dependent on various hydraulic (and other) properties, in particular the effective permeability of the wellbore and the magnitude of pressure increase. If brine flow occurs outside of the well casing, e.g., in a permeable fracture zone between the well cement and the formation, the fluid/solute transfer between the migrating fluid and the surrounding rock units can strongly retard brine flow. At the same time, the threshold pressure for continuous flow to occur decreases compared to a case with no fluid/solute transfer.

  20. Optimization of satellite coverage in observing cause and effect changes in the ionosphere, magnetosphere, and solar wind. Master's thesis

    SciTech Connect (OSTI)

    Loveless, M.J.

    1993-06-01

    Disturbances in the ionosphere sometimes cause adverse effects to communications systems, power grids, etc. on the earth. Currently, very little, if any, lead time is given to warn of an impending problem. If a forecast could be made of ionospheric occurrences, some lead time may be given to appropriate agencies and equipment may be saved. Most changes that occur in the ionosphere are a result of interaction of energy, currents, etc. between the magnetosphere and/or solar wind. Before a forecast can be made, however, improvement of ionospheric models currently in use need to be made. The models currently depict features in various regions of the ionosphere but not always where these features are actually observed. So an improvement to the model is needed to create an accurate baseline condition, or in other words an accurate depiction of the current ionosphere. Models could be improved by inputting real-time data from the ionosphere into the model. This data would come from satellites and/or ground-based stations.

  1. Early life ethanol exposure causes long-lasting disturbances in rat mesenchymal stem cells via epigenetic modifications

    SciTech Connect (OSTI)

    Leu, Yu-Wei; Chu, Pei-Yi; Chen, Chien-Min; Yeh, Kun-Tu; Liu, Yu Ming; Lee, Yen-Hui; Kuo, Shan-Tsu; Hsiao, Shu-Huei

    2014-10-24

    Highlights: • Ethanol exposure alters proliferation and differentiation of MSCs. • Ethanol exposure suppresses osteogenesis and adipogenesis of MSCs. • H3K27me3-associated genes/pathways are affected in ethanol-exposed MSCs. • Expression of lineage-specific genes is dysregulated in ethanol-exposed MSCs. - Abstract: Fetal alcohol syndrome (FAS) is a birth defect due to maternal alcohol consumption during pregnancy. Because mesenchymal stem cells (MSCs) are the main somatic stem cells in adults and may contribute to tissue homeostasis and repair in adulthood, we investigated whether early life ethanol exposure affects MSCs and contributes to the propensity for disease onset in later life. Using a rodent model of FAS, we found that ethanol exposure (5.25 g/kg/day) from postnatal days 4 to 9 in rat pups (mimic of human third trimester) caused long-term anomalies in bone marrow-derived MSCs. MSCs isolated from ethanol-exposed animals were prone to neural induction but resistant to osteogenic and adipogenic inductions compared to their age-matched controls. The altered differentiation may contribute to the severe trabecular bone loss seen in ethanol-exposed animals at 3 months of age as well as overt growth retardation. Expression of alkaline phosphatase, osteocalcin, aP2, and PPARγ were substantially inhibited, but BDNF was up-regulated in MSCs isolated from ethanol-exposed 3 month-old animals. Several signaling pathways were distorted in ethanol-exposed MSCs via altered trimethylation at histone 3 lysine 27. These results demonstrate that early life ethanol exposure can have long-term impacts in rat MSCs by both genetic and epigenetic mechanisms.

  2. The p150 subunit of CAF-1 causes association of SUMO2/3 with the DNA replication foci

    SciTech Connect (OSTI)

    Uwada, Junsuke; Global COE Program, Global Initiative Center for Pulsed Power Engineering, Kumamoto University, 2-39-1 Kurokami, Kumamoto 860-8555 ; Tanaka, Niina; Yamaguchi, Yutaro; Uchimura, Yasuhiro; Shibahara, Kei-ichi; Nakao, Mitsuyoshi; Saitoh, Hisato; Global COE Program, Global Initiative Center for Pulsed Power Engineering, Kumamoto University, 2-39-1 Kurokami, Kumamoto 860-8555

    2010-01-01

    The small ubiquitin-related modifier 2/3 (SUMO2/3) can be post-translationally conjugated to a wide variety of proteins constituting chromatin, the platform for genetic and epigenetic regulation. Nevertheless, it is unclear how SUMO2/3 and SUMO2/3-modified proteins are delivered to the chromatin fibers. Here we report that the largest subunit of chromatin assembly factor 1 (CAF-1), human p150, interacts directly and preferentially with SUMO2/3. Amino acid residue of 98-105 in p150 is essential and sufficient for SUMO2/3 interaction. p150-SUMO2/3 interaction coincided with regions that replicate chromatin fibers, because accumulation of the proliferating cell nuclear antigen (PCNA), and incorporation of bromodeoxyuridine (BrdU) were detected at foci co-localized with both p150 and SUMO2/3 during the S-phase in a cell line expressing epitope-tagged p150. Although inhibition of SUMO2/3 expression had only a small effect on p150 deposition on the replication sites, depletion of p150 led to delocalization of SUMO2/3 from the replication foci. Furthermore, p150 mutants deficient in SUMO2/3 interaction, caused a major reduction of SUMO2/3 at the replication foci. Thus, our findings suggest an expanded role of p150 as a SUMO2/3-interacting factor, and raise the intriguing possibility that p150 plays a role in promoting delivery of SUMO2/3 or SUMO2/3-modified proteins (or both) on chromatin fibers during replication.

  3. Ion-temperature-gradient sensitivity of the hydrodynamic instability caused by shear in the magnetic-field-aligned plasma flow

    SciTech Connect (OSTI)

    Mikhailenko, V. V.; Mikhailenko, V. S.; Lee, Hae June; Koepke, M. E.

    2014-07-15

    The cross-magnetic-field (i.e., perpendicular) profile of ion temperature and the perpendicular profile of the magnetic-field-aligned (parallel) plasma flow are sometimes inhomogeneous for space and laboratory plasma. Instability caused either by a gradient in the ion-temperature profile or by shear in the parallel flow has been discussed extensively in the literature. In this paper, (1) hydrodynamic plasma stability is investigated, (2) real and imaginary frequency are quantified over a range of the shear parameter, the normalized wavenumber, and the ratio of density-gradient and ion-temperature-gradient scale lengths, and (3) the role of inverse Landau damping is illustrated for the case of combined ion-temperature gradient and parallel-flow shear. We find that increasing the ion-temperature gradient reduces the instability threshold for the hydrodynamic parallel-flow shear instability, also known as the parallel Kelvin-Helmholtz instability or the D'Angelo instability. We also find that a kinetic instability arises from the coupled, reinforcing action of both free-energy sources. For the case of comparable electron and ion temperature, we illustrate analytically the transition of the D'Angelo instability to the kinetic instability as (a) the shear parameter, (b) the normalized wavenumber, and (c) the ratio of density-gradient and ion-temperature-gradient scale lengths are varied and we attribute the changes in stability to changes in the amount of inverse ion Landau damping. We show that near a normalized wavenumber k{sub ?}?{sub i} of order unity (i) the real and imaginary values of frequency become comparable and (ii) the imaginary frequency, i.e., the growth rate, peaks.

  4. The case for a cause-effect linkage between environmental contamination and development in eggs of the common snapping turtle (Chelydra S. serpentina) from Ontario, Canada

    SciTech Connect (OSTI)

    Bishop, C.A.; Brooks, R.J.; Carey, J.H.; Ng, P.; Norstrom, R.J.; Lean, D.R. )

    1991-08-01

    Concentrations of polychlorinated biphenyls (PCBs), dibenzo-p-dioxins, and dibenzofurans, organochlorine pesticides, and their metabolites were measured in eggs of the common snapping turtle (Chelydra s.serpentina) collected from four wetlands on the shorelines of Lakes Ontario, and Erie, and one control location in central Ontario, Canada. Snapping turtle eggs from these sites were also artificially incubated to determine hatching success, and incidence of deformities in embryo and hatchling turtles. The hypothesis that elevated incidences of egg death and/or deformities of hatchling turtles would occur in populations with high concentrations of organochlorine contaminants in eggs was tested. The results were elevated using epidemiological criteria. Unhatched eggs and deformities occurred at significantly higher rates in eggs from Lake Ontario wetlands. Two of three sites from Lake Ontario had substantially higher levels of PCBs, dioxins, and furans compared to eggs from Lake Erie and the control site. It could not be shown that contamination of eggs preceded the occurrence of poor development of eggs, although excellent hatching success and low numbers of deformities in eggs from the control site were considered representative of development in healthy eggs. The statistical association between contaminant levels in eggs and poor development of these eggs supported the hypothesis that eggs from sites with the greatest contamination had the highest rates of abnormalities. PCBs were the most strongly associated chemicals, although possible effects due to the presence of other chemicals in eggs was a confounding factor. The deformities and rates of unhatched eggs were similar to those occurring in other vertebrates collected from highly contaminated areas of the Great Lakes. 54 references.

  5. Exposure to monocrotophos pesticide during sexual development causes the feminization/demasculinization of the reproductive traits and a reduction in the reproductive success of male guppies (Poecilia reticulata)

    SciTech Connect (OSTI)

    Tian, Hua; Li, Yun; Wang, Wei; Wu, Peng; Ru, Shaoguo

    2012-09-01

    Monocrotophos is a highly toxic organophosphorus pesticide that has been confirmed to be an endocrine‐disrupting chemical. To evaluate the influence of this pollutant on the reproductive system of male fish, we studied the sex steroid levels, reproductive traits, sex ratio, and reproductive success in male guppies (Poecilia reticulata) exposed to 40% monocrotophos pesticide at the nominal concentrations of 0.01, 0.10, and 1.00 mg/L for 90 days from birth to adulthood in a semi‐static exposure system. Radioimmunoassay and western blot analyses demonstrated that the long‐term exposure to monocrotophos pesticide during the sexual development of male guppies caused a significant increase in 17β‐estradiol levels and consequently induced vitellogenin synthesis, suggesting the feminization of the males. Monocrotophos pesticide also caused a significant decrease in testosterone levels, which consequently inhibited testis growth and reduced the sperm count and the area and intensity of their sexually attractive orange spots, which collectively indicated the significant demasculinization of the male sexual characteristics. Furthermore, these changes in the sexual characteristics at the cellular and organ levels translated into ecologically important effects on the reproductive success at the individual level, as measured by a decrease in offspring production and survival rate. The present study provides the first evidence that monocrotophos pesticide can cause severe reproductive abnormalities in fish due to its endocrine‐disrupting action. -- Highlights: ► Monocrotophos pesticide caused an increase in 17β‐estradiol levels of male guppies. ► Monocrotophos pesticide induced vitellogenin synthesis of male guppies. ► Monocrotophos pesticide caused a decrease in testosterone levels of male guppies. ► Monocrotophos pesticide caused demasculinization of male sexual characteristics. ► Monocrotophos pesticide caused a reduction in reproductive success of male

  6. The probability of laser caused ocular injury to the aircrew of undetected aircraft violating the exclusion zone about the airborne aura LIDAR.

    SciTech Connect (OSTI)

    Augustoni, Arnold L.

    2006-12-01

    The probability of a laser caused ocular injury, to the aircrew of an undetected aircraft entering the exclusion zone about the AURA LIDAR airborne platform with the possible violation of the Laser Hazard Zone boundary, was investigated and quantified for risk analysis and management.

  7. Sequencing and fan-out mechanism for causing a set of at least two sequential instructions to be performed in a dataflow processing computer

    DOE Patents [OSTI]

    Grafe, Victor G.; Hoch, James E.

    1993-01-01

    A sequencing and data fanout mechanism is provided for a dataflow processor is activated by an input token which causes a sequence of operations to occur by initiating a first instruction to act on data contained within the token and then executing a sequential thread of instructions identified by either a repeat count and an offset within the token, or by an offset within each preceding instruction.

  8. Tamoxifen affects glucose and lipid metabolism parameters, causes browning of subcutaneous adipose tissue and transient body composition changes in C57BL/6NTac mice

    SciTech Connect (OSTI)

    Hesselbarth, Nico; Pettinelli, Chiara; Gericke, Martin; Berger, Claudia; Kunath, Anne; Stumvoll, Michael; Blüher, Matthias; Klöting, Nora

    2015-08-28

    Tamoxifen is a selective estrogen receptor (ER) modulator which is widely used to generate inducible conditional transgenic mouse models. Activation of ER signaling plays an important role in the regulation of adipose tissue (AT) metabolism. We therefore tested the hypothesis that tamoxifen administration causes changes in AT biology in vivo. 12 weeks old male C57BL/6NTac mice were treated with either tamoxifen (n = 18) or vehicle (n = 18) for 5 consecutive days. Tamoxifen treatment effects on body composition, energy homeostasis, parameters of AT biology, glucose and lipid metabolism were investigated up to an age of 18 weeks. We found that tamoxifen treatment causes: I) significantly increased HbA{sub 1c}, triglyceride and free fatty acid serum concentrations (p < 0.01), II) browning of subcutaneous AT and increased UCP-1 expression, III) increased AT proliferation marker Ki67 mRNA expression, IV) changes in adipocyte size distribution, and V) transient body composition changes. Tamoxifen may induce changes in body composition, whole body glucose and lipid metabolism and has significant effects on AT biology, which need to be considered when using Tamoxifen as a tool to induce conditional transgenic mouse models. Our data further suggest that tamoxifen-treated wildtype mice should be characterized in parallel to experimental transgenic models to control for tamoxifen administration effects. - Highlights: • Tamoxifen treatment causes significantly increased HbA{sub 1c}, triglyceride and free fatty acid serum concentrations. • Tamoxifen induces browning of subcutaneous AT and increased UCP-1 expression. • Tamoxifen changes adipocyte size distribution, and transient body composition.

  9. Method and apparatus for identifying conductive objects by monitoring the true resistive component of impedance change in a coil system caused by the object

    DOE Patents [OSTI]

    Gregory, William D.; Capots, Larry H.; George, James P.; Janik, Richard

    1981-01-01

    The type of conductor, its property, and if a metal, its type and cross-sectional area can be obtained from measurements made at different frequencies for the amount of unbalance created in a previously balanced stable coil detection system. The true resistive component is accurately measured and thus reflects only the voltage loss attributable to eddy currents caused by introduction of the test sample to the coil system. This voltage divided by corresponding applied frequency gives a curve which peaks at a frequency dependent upon type of conductor. For a metal this peak frequency is proportional to the samples resistivity divided by its cross-sectional area.

  10. Measurements of the reduced force coefficients for H{sub 2}, N{sub 2}, CO, and CO{sub 2} incident upon a solar panel array material, SiO{sub 2}-coated Kapton, Kapton, and Z-93-coated Al

    SciTech Connect (OSTI)

    Cook, S.R.; Hoffbauer, M.A.; Clark, D.D.; Cross, J.B.

    1998-07-01

    The reduced force coefficients were measured for H{sub 2}, N{sub 2}, CO, and CO{sub 2} incident upon a solar panel array material, SiO{sub 2}-coated Kapton, Kapton, and Z-93-coated Al. The coefficients were determined by measuring both the magnitude and direction of the force exerted on the surfaces by molecular beams of the gases. Measurements were made at angles of incidence of 0{degree}, 25{degree}, 50{degree}, 75{degree}, and 85{degree}. The forces were measured using a torsion balance with the surfaces mounted on the end of the lever arm. The absolute flux densities of the molecular beams were measured using a second torsion balance with a beam stop mounted on the lever arm that nullified the force of the scattered molecules. Flux measurements were also made using the effusive method. Standard time-of-flight techniques were used to determine the flux-weighted average velocities of the molecular beams. These velocities ranged from 1670 to 4620 m/s. The overall uncertainty in the reduced force coefficient measurements was estimated to be less than {plus_minus}10{percent}. These measurements were used to obtain the magnitude and direction of the flux-weighted average velocity of the scattered molecules, and also the flux-weighted translational kinetic energy of the scattered molecules. Analysis of this information provided insight into the microscopic details of the gas-surface interaction potential energy surface. {copyright} {ital 1998} {ital The American Physical Society}

  11. A second mutation in the type II procollagen gene (COL2A1) causing Stickler syndrome (arthro-ophthalmopathy) is also a premature termination codon

    SciTech Connect (OSTI)

    Ahmad, N.N.; Knowlton, R.G.; DiMascio, J.; Prockop, D.J. ); McDonald-McGinn, D.M.; Zackai, E.H.; LaRossa, D. )

    1993-01-01

    Genetic linkage analyses suggest that mutations in type II collagen may be responsible for Stickler syndrome, or arthro-ophthalmopathy (AO), in many families. In the present study oligonucleotide primers were developed to amplify and directly sequence eight of the first nine exons of the gene for type II procollagen (COL2A1). Analysis of the eight exons in 10 unrelated probands with AO revealed that one had a single-base mutation in one allele that changed the codon of -CGA- for arginine at amino acid position [alpha]1-9 in exon 7 to a premature termination signal for translation. The second mutation found to cause AO was, therefore, similar to the first in that both created premature termination signals in the COL2A1 gene. Since mutations producing premature termination signals have not previously been detected in genes for fibrillar collagens, the results raise the possibility that such mutations in the COL2A1 gene are a common cause of AO. 33 refs., 4 figs., 2 tabs.

  12. Determination of the effects caused by different polymers on coal fluidity during carbonization using high-temperature {sup 1}H NMR and rheometry

    SciTech Connect (OSTI)

    Miguel Castro Diaz; Lucky Edecki; Karen M. Steel; John W. Patrick; Colin E. Snape

    2008-01-15

    The effects of blending polyethylene (PE), polystyrene (PS), poly(ethyleneterephthalate) (PET), a flexible polyurethane (FPU), and a car shredded fluff waste (CSF) on fluidity development of a bituminous coal during carbonization have been studied by means of high-torque, small-amplitude controlled-strain rheometry and in situ high-temperature {sup 1}H NMR spectroscopy. The most detrimental effects were caused by PET and PS, which completely destroyed the fluidity of the coal. The CSF had a deleterious effect on coal fluidity similar to that of PET, although the deleterious effect on the viscoelastic properties of the coal were less pronounced than those of PET and PS. On the contrary, the addition of 10 wt % PE caused a slight reduction in the concentration of fluid hydrogen and an increase in the minimum complex viscosity, and the addition of 10 wt % FPU reduced the concentration of fluid hydrogen without changing the viscoelastic properties of the coal. Although these results suggest that these two plastics could potentially be used as additives in coking blends without compromising coke porosity, it was found that the semicoke strengths were reduced by adding 2 wt % FPU and 5 wt % PE. Therefore, it is unlikely that more than 2 wt % of a plastic waste could be added to a coal blend without deterioration in coke quality. 35 refs., 11 figs., 3 tabs.

  13. Investigation of EMIC wave scattering as the cause for the BARREL 17 January 2013 relativistic electron precipitation event: A quantitative comparison of simulation with observations

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Li, Zan; Millan, Robyn M.; Hudson, Mary K.; Woodger, Leslie A.; Smith, David M.; Chen, Yue; Friedel, Reiner; Rodriguez, Juan V.; Engebretson, Mark J.; Goldstein, Jerry; et al

    2014-12-23

    Electromagnetic ion cyclotron (EMIC) waves were observed at multiple observatory locations for several hours on 17 January 2013. During the wave activity period, a duskside relativistic electron precipitation (REP) event was observed by one of the Balloon Array for Radiation belt Relativistic Electron Losses (BARREL) balloons and was magnetically mapped close to Geostationary Operational Environmental Satellite (GOES) 13. We simulate the relativistic electron pitch angle diffusion caused by gyroresonant interactions with EMIC waves using wave and particle data measured by multiple instruments on board GOES 13 and the Van Allen Probes. We show that the count rate, the energy distribution,more » and the time variation of the simulated precipitation all agree very well with the balloon observations, suggesting that EMIC wave scattering was likely the cause for the precipitation event. The event reported here is the first balloon REP event with closely conjugate EMIC wave observations, and our study employs the most detailed quantitative analysis on the link of EMIC waves with observed REP to date.« less

  14. Investigation of EMIC wave scattering as the cause for the BARREL 17 January 2013 relativistic electron precipitation event: A quantitative comparison of simulation with observations

    SciTech Connect (OSTI)

    Li, Zan; Millan, Robyn M.; Hudson, Mary K.; Woodger, Leslie A.; Smith, David M.; Chen, Yue; Friedel, Reiner; Rodriguez, Juan V.; Engebretson, Mark J.; Goldstein, Jerry; Fennell, Joseph F.; Spence, Harlan E.

    2014-12-23

    Electromagnetic ion cyclotron (EMIC) waves were observed at multiple observatory locations for several hours on 17 January 2013. During the wave activity period, a duskside relativistic electron precipitation (REP) event was observed by one of the Balloon Array for Radiation belt Relativistic Electron Losses (BARREL) balloons and was magnetically mapped close to Geostationary Operational Environmental Satellite (GOES) 13. We simulate the relativistic electron pitch angle diffusion caused by gyroresonant interactions with EMIC waves using wave and particle data measured by multiple instruments on board GOES 13 and the Van Allen Probes. We show that the count rate, the energy distribution, and the time variation of the simulated precipitation all agree very well with the balloon observations, suggesting that EMIC wave scattering was likely the cause for the precipitation event. The event reported here is the first balloon REP event with closely conjugate EMIC wave observations, and our study employs the most detailed quantitative analysis on the link of EMIC waves with observed REP to date.

  15. Retrospective Evaluation Reveals That Long-term Androgen Deprivation Therapy Improves Cause-Specific and Overall Survival in the Setting of Dose-Escalated Radiation for High-Risk Prostate Cancer

    SciTech Connect (OSTI)

    Feng, Felix Y.; Blas, Kevin; Olson, Karin; Stenmark, Matthew; Sandler, Howard; Hamstra, Daniel A.

    2013-05-01

    Purpose: To evaluate the role of androgen deprivation therapy (ADT) and duration for high-risk prostate cancer patients treated with dose-escalated radiation therapy (RT). Methods and Materials: A retrospective analysis of high-risk prostate cancer patients treated with dose-escalated RT (minimum 75 Gy) with or without ADT was performed. The relationship between ADT use and duration with biochemical failure (BF), metastatic failure (MF), prostate cancer-specific mortality (PCSM), non-prostate cancer death (NPCD), and overall survival (OS) was assessed as a function of pretreatment characteristics, comorbid medical illness, and treatment using Fine and Gray's cumulative incidence methodology. Results: The median follow-up time was 64 months. In men with National Comprehensive Cancer Network defined high-risk prostate cancer treated with dose-escalated RT, on univariate analysis, both metastasis (P<.0001; hazard ratio 0.34; 95% confidence interval 0.18-0.67; cumulative incidence at 60 months 13% vs 35%) and PCSM (P=.015; hazard ratio 0.41; 95% confidence interval 0.2-1.0; cumulative incidence at 60 months 6% vs 11%) were improved with the use of ADT. On multivariate analysis for all high-risk patients, Gleason score was the strongest negative prognostic factor, and long-term ADT (LTAD) improved MF (P=.002), PCSM (P=.034), and OS (P=.001). In men with prostate cancer and Gleason scores 8 to 10, on multivariate analysis after adjustment for other risk features, there was a duration-dependent improvement in BF, metastasis, PCSM, and OS, all favoring LTAD in comparison with STAD or RT alone. Conclusion: For men with high-risk prostate cancer treated with dose-escalated EBRT, this retrospective study suggests that the combination of LTAD and RT provided a significant improvement in clinical outcome, which was especially true for those with Gleason scores of 8 to 10.

  16. HYDRODYNAMIC AND RADIATIVE MODELING OF TEMPORAL H{alpha} EMISSION V/R VARIATIONS CAUSED BY DISCONTINUOUS MASS TRANSFER IN BINARIES

    SciTech Connect (OSTI)

    Chadima, Pavel; Harmanec, Petr; Wolf, Marek; Firt, Roman; Ruzdjak, Domagoj; Bozic, Hrvoje; Koubsky, Pavel

    2011-07-15

    H{alpha} emission V/R variations caused by discontinuous mass transfer in interacting binaries with a rapidly rotating accreting star are modeled qualitatively for the first time. The program ZEUS-MP was used to create a non-linear three-dimensional hydrodynamical model of a development of a blob of gaseous material injected into an orbit around a star. It resulted in the formation of an elongated disk with a slow prograde revolution. The LTE radiative transfer program SHELLSPEC was used to calculate the H{alpha} profiles originating in the disk for several phases of its revolution. The profiles have the form of a double emission and exhibit V/R and radial velocity variations. However, these variations should be a temporal phenomenon since imposing a viscosity in the given model would lead to a circularization of the disk and fading-out of the given variations.

  17. Interference fringes of m=0 spin states under the Majorana transition caused by rapid half-rotation of a magnetic field

    SciTech Connect (OSTI)

    Takahashi, Atsushi; Morinaga, Atsuo

    2010-04-15

    The phase shift and visibility of fringes in the Ramsey atom interferometer composed of the |F=1,m{sub F}=0> and |F=2,m{sub F}=0> states were examined systematically for rapid half-rotation of the magnetic field. It was verified that the phase shifts by {pi} rad in the adiabatic regime, but it does not shift from the original one in the nonadiabatic regime. These results support Robbins and Berry's claim [J. M. Robbins and M. V. Berry, J. Phys. A 27, L435 (1994)]. The fact that the interference fringes disappear in the intermediate regime and reappear in the nonadiabatic regime can be explained by the Majorana transition caused by a rapid reverse of the magnetic field.

  18. Ethanol-induced impairment of polyamine homeostasis – A potential cause of neural tube defect and intrauterine growth restriction in fetal alcohol syndrome

    SciTech Connect (OSTI)

    Haghighi Poodeh, Saeid; Alhonen, Leena; Salonurmi, Tuire; Savolainen, Markku J.

    2014-03-28

    Highlights: • Polyamine pools in embryonic and extraembryonic tissues are developmentally regulated. • Alcohol administration perturbs polyamine levels in the tissues with various patterns. • Total absence of polyamines in the embryo head at 9.5 dpc is critical for development. • The deficiency is associated with reduction in endothelial cell sprouting in the head. • Retarded migration of neural crest cells may cause development of neural tube defect. - Abstract: Introduction: Polyamines play a fundamental role during embryogenesis by regulating cell growth and proliferation and by interacting with RNA, DNA and protein. The polyamine pools are regulated by metabolism and uptake from exogenous sources. The use of certain inhibitors of polyamine synthesis causes similar defects to those seen in alcohol exposure e.g. retarded embryo growth and endothelial cell sprouting. Methods: CD-1 mice received two intraperitoneal injections of 3 g/kg ethanol at 4 h intervals 8.75 days post coitum (dpc). The fetal head, trunk, yolk sac and placenta were collected at 9.5 and 12.5 dpc and polyamine concentrations were determined. Results: No measurable quantity of polyamines could be detected in the embryo head at 9.5 dpc, 12 h after ethanol exposure. Putrescine was not detectable in the trunk of the embryo at that time, whereas polyamines in yolk sac and placenta were at control level. Polyamine deficiency was associated with slow cell growth, reduction in endothelial cell sprouting, an altered pattern of blood vessel network formation and consequently retarded migration of neural crest cells and growth restriction. Discussion: Our results indicate that the polyamine pools in embryonic and extraembryonic tissues are developmentally regulated. Alcohol administration, at the critical stage, perturbs polyamine levels with various patterns, depending on the tissue and its developmental stage. The total absence of polyamines in the embryo head at 9.5 dpc may explain why this

  19. Sodium orthovanadate associated with pharmacological doses of ascorbate causes an increased generation of ROS in tumor cells that inhibits proliferation and triggers apoptosis

    SciTech Connect (OSTI)

    Gnther, T-hat nia Mara Fischer; Kviecinski, Maicon Roberto; Baron, Carla Cristine; Felipe, Karina Bettega; Farias, Mirelle Sifroni; Ourique da Silva, Fabiana; Bcker, Ndia Cristina Falco; Pich, Claus Trger; Ferreira, Eduardo Antonio; Filho, Danilo Wilhelm; Verrax, Julien; Calderon, Pedro Buc; Pedrosa, Rozangela Curi

    2013-01-18

    Graphical abstract: -- Abstract: Pharmacological doses of ascorbate were evaluated for its ability to potentiate the toxicity of sodium orthovanadate (Na{sub 3}VO{sub 4}) in tumor cells. Cytotoxicity, inhibition of cell proliferation, generation of ROS and DNA fragmentation were assessed in T24 cells. Na{sub 3}VO{sub 4} was cytotoxic against T24 cells (EC{sub 50} = 5.8 ?M at 24 h), but in the presence of ascorbate (100 ?M) the EC{sub 50} fell to 3.3 ?M. Na{sub 3}VO{sub 4} plus ascorbate caused a strong inhibition of cell proliferation (up to 20%) and increased the generation of ROS (4-fold). Na{sub 3}VO{sub 4} did not directly cleave plasmid DNA, at this aspect no synergism was found occurring between Na{sub 3}VO{sub 4} and ascorbate once the resulting action of the combination was no greater than that of both substances administered separately. Cells from Ehrlich ascites carcinoma-bearing mice were used to determine the activity of antioxidant enzymes, the extent of the oxidative damage and the type of cell death. Na{sub 3}VO{sub 4} alone, or combined with ascorbate, increased catalase activity, but only Na{sub 3}VO{sub 4} plus ascorbate increased superoxide dismutase activity (up to 4-fold). Oxidative damage on proteins and lipids was higher due to the treatment done with Na{sub 3}VO{sub 4} plus ascorbate (23-fold). Ascorbate potentiated apoptosis in tumor cells from mice treated with Na{sub 3}VO{sub 4}. The results indicate that pharmacological doses of ascorbate enhance the generation of ROS induced by Na{sub 3}VO{sub 4} in tumor cells causing inhibition of proliferation and apoptosis. Apoptosis induced by orthovanadate and ascorbate is closer related to inhibition on Bcl-xL and activation of Bax. Our data apparently rule out a mechanism of cell demise p53-dependent or related to Cdk2 impairment.

  20. The Effect of Early Detection of Occult Brain Metastases in HER2-Positive Breast Cancer Patients on Survival and Cause of Death

    SciTech Connect (OSTI)

    Niwinska, Anna; Tacikowska, Malgorzata; Murawska, Magdalena

    2010-07-15

    Purpose: The aim of the study is to evaluate disease-free survival, survival from the detection of brain metastases, overall survival, and cause of death in patients with occult brain metastases (Group I) vs. patients with symptomatic brain metastases (Group II). Methods and Materials: In 80 HER2-positive breast cancer patients, treated with trastuzumab and cytostatic agents for metastatic disease, magnetic resonance imaging screening of the brain was performed, and in 29 patients (36%) occult brain metastasis was detected (Group I). Whole-brain radiotherapy was delivered to Group I. This first group was compared with 52 patients who had symptomatic brain metastases (Group II) and was treated the same way, at the same clinic, during the same time period. Results: Median disease-free survival was 17 months in Group I and 19.9 months in Group II (p = 0.58). The median time interval between the dissemination of the disease and the detection of occult or symptomatic brain metastases was 9 and 15 months, respectively (p = 0.11). When the brain metastases were detected, the median survival was 9 and 8.78 months, respectively (p = 0.80). The median overall survival was 53 and 51 months, respectively (p = 0.94). In the group with occult brain metastases (Group I) 16% of patients died because of progression within the brain. In the group with symptomatic brain metastases (Group II) the rate of cerebral death was 48% (p = 0.009). Conclusions: Whole-brain radiotherapy of occult brain metastases in HER2-positive breast cancer patients with visceral dissemination produces a three-fold decrease in cerebral deaths but does not prolong survival.

  1. --No Title--

    Gasoline and Diesel Fuel Update (EIA)

    . Electricity Consumption (kWh) by End Use for Non-Mall Buildings, 2003 Total Electricity Consumption (billion kWh) Total Space Heat- ing Cool- ing Venti- lation Water Heat- ing...

  2. --No Title--

    Gasoline and Diesel Fuel Update (EIA)

    E3A. Electricity Consumption (Btu) by End Use for All Buildings, 2003 Total Electricity Consumption (trillion Btu) Total Space Heat- ing Cool- ing Venti- lation Water Heat- ing...

  3. ORISE: REAC/TS Radiological Incident Medical Consultation

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Radiation Emergency Assistance CenterTraining Site (REACTS), ORISE provides advice and consultation to emergency personnel responsible for the medical management of radiation ...

  4. NNSA Nuclear/Radiological Incident Response | National Nuclear...

    National Nuclear Security Administration (NNSA)

    use and interpretation of specialized radiation detection equipment; core technical ... Aerial Measuring System (AMS) - AMS characterizes ground-deposited radiation from aerial ...

  5. Oscillations of a Turbulent Jet Incident Upon an Edge

    SciTech Connect (OSTI)

    J.C. Lin; D. Rockwell

    2000-09-19

    For the case of a jet originating from a fully turbulent channel flow and impinging upon a sharp edge, the possible onset and nature of coherent oscillations has remained unexplored. In this investigation, high-image-density particle image velocimetry and surface pressure measurements are employed to determine the instantaneous, whole-field characteristics of the turbulent jet-edge interaction in relation to the loading of the edge. It is demonstrated that even in absence of acoustic resonant or fluid-elastic effects, highly coherent, self-sustained oscillations rapidly emerge above the turbulent background. Two clearly identifiable modes of instability are evident. These modes involve large-scale vortices that are phase-locked to the gross undulations of the jet and its interaction with the edge, and small-scale vortices, which are not phase-locked. Time-resolved imaging of instantaneous vorticity and velocity reveals the form, orientation, and strength of the large-scale concentrations of vorticity approaching the edge in relation to rapid agglomeration of small-scale vorticity concentrations. Such vorticity field-edge interactions exhibit rich complexity, relative to the simplified pattern of vortex-edge interaction traditionally employed for the quasi-laminar edgetone. Furthermore, these interactions yield highly nonlinear surface pressure signatures. The origin of this nonlinearity, involving coexistence of multiple frequency components, is interpreted in terms of large- and small-scale vortices embedded in distributed vorticity layers at the edge. Eruption of the surface boundary layer on the edge due to passage of the large-scale vortex does not occur; rather apparent secondary vorticity concentrations are simply due to distension of the oppositely-signed vorticity layer at the tip of the edge. The ensemble-averaged turbulent statistics of the jet quickly take on an identity that is distinct from the statistics of the turbulent boundary layer in the channel. Large increases in Reynolds stress occur due to onset of the small-scale concentrations of vorticity immediately downstream of separation; substantial increases at locations further downstream arise from development of the large-scale vorticity concentrations.

  6. ORISE: Incident Management Training Put to Test in Gulf

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    response, was critical to a productive effort. Adhering to a common framework for command and control minimized confusion and allowed multiple agencies to work together. At...

  7. Model Annex for Preparedness and Response to Radiological Transportation Incidents

    Broader source: Energy.gov [DOE]

    This part should contain a general statement of the intent of this Annex. To provide for the planning, preparedness and coordination of emergency service efforts to respond to a transportation...

  8. Fact Sheet Investigation of Incident at Waste Isolation Pilot...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Isolation Pilot Plant (WIPP) underground repository resulted in the release of radioactive material into the environment and contaminated 21 people with low-level radioactivity. ...

  9. Environment/Health/Safety (EHS): Report an Accident or Incident

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    or 9-911 immediately or the emergency number on your desk phone if off site. Please stay on the line until it is answered. If calling from a cellular phone, call 911 and be...

  10. NNSA Nuclear/Radiological Incident Response | National Nuclear...

    National Nuclear Security Administration (NNSA)

    Accident Response Group (ARG) - The ARG response element is comprised of scientists, ... equipment ready for short-notice dispatch to the scene of a U.S. nuclear weapon accident. ...

  11. Measuring Human Performance within Computer Security Incident Response Teams

    SciTech Connect (OSTI)

    McClain, Jonathan T.; Silva, Austin Ray; Avina, Glory Emmanuel; Forsythe, James C.

    2015-09-01

    Human performance has become a pertinen t issue within cyber security. However, this research has been stymied by the limited availability of expert cyber security professionals. This is partly attributable to the ongoing workload faced by cyber security professionals, which is compound ed by the limited number of qualified personnel and turnover of p ersonnel across organizations. Additionally, it is difficult to conduct research, and particularly, openly published research, due to the sensitivity inherent to cyber ope rations at most orga nizations. As an alternative, the current research has focused on data collection during cyb er security training exercises. These events draw individuals with a range of knowledge and experience extending from seasoned professionals to recent college gradu ates to college students. The current paper describes research involving data collection at two separate cyber security exercises. This data collection involved multiple measures which included behavioral performance based on human - machine transactions and questionnaire - based assessments of cyber security experience.

  12. Performance of Silicon Pixel Detectors at Small Track Incidence...

    Office of Scientific and Technical Information (OSTI)

    Inst. ; Wolf, Julian ; LBL, Berkeley UC, Berkeley ; Wu, Sau Lan ; Yang, Hongtao more ; Wisconsin U., Madison less Publication Date: 2016-04-18 OSTI Identifier: 1248541 ...

  13. Normal incidence x-ray mirror for chemical microanalysis

    DOE Patents [OSTI]

    Carr, M.J.; Romig, A.D. Jr.

    1987-08-05

    An x-ray mirror for both electron column instruments and micro x-ray fluorescence instruments for making chemical, microanalysis comprises a non-planar mirror having, for example, a spherical reflecting surface for x-rays comprised of a predetermined number of alternating layers of high atomic number material and low atomic number material contiguously formed on a substrate and whose layers have a thickness which is a multiple of the wavelength being reflected. For electron column instruments, the wavelengths of interest lie above 1.5nm, while for x-ray fluorescence instruments, the range of interest is below 0.2nm. 4 figs.

  14. EM-Led Radiological Incident Response Program Receives Honors | Department

    Office of Environmental Management (EM)

    EM's Year in Review at Savannah River Site EM's Year in Review at Savannah River Site December 23, 2014 - 12:00pm Addthis This photo shows the dissolution of fuel from the Sodium Reactor Experiment Campaign in H-Canyon. This photo shows the dissolution of fuel from the Sodium Reactor Experiment Campaign in H-Canyon. AIKEN, S.C. - The EM program at the Savannah River Site (SRS) achieved many accomplishments in 2014: Dissolved fuel in the Sodium Reactor Experiment Campaign in H-Canyon; the fuel in

  15. Structure and Dynamics of Polymer Nanocomposites by Grazing-Incidence...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Presented at the High Temperature Membrane Working Group (HTMWG) Meeting held on October ... FY 2004 LDRD Report Minutes of the High Temperature Membrane Working Group Meeting

  16. Enteric viruses in a mangrove lagoon, survival and shellfish incidence

    SciTech Connect (OSTI)

    Lopez de Cardona, I.; Bermudez, M.; Billmire, E.; Hazen, T.C.

    1988-12-31

    Mangrove oysters (Crassostrea rhizophorae) were screened for enteric viruses. For 18 months oysters were collected from Cano Boqueron, a tropical mangrove lagoon on the southwest coast of Puerto Rico. This popular tourist resort has two primary sewage treatment plants which service 158 single family cabanas. In spite of the heavy seasonal input of sewage to Cano Boqueron and high densities of fecal coliform bacteria, enteric viruses were not detected in shellfish meat. Because no viruses were detected in the oysters, a virus survival study was performed. Poliovirus type 1 was placed in diffusion chambers in situ at two sites in Cano Boqueron. More than 95% of the poliovirus inactivation occurred within 24 h. Virus inactivation was significantly different by site, indicating different inactivation rates within the lagoon. Chamber studies done simultaneously with Escherichia coli did not reveal differences between sites. It is suggested that the sewage effluent had an antiviral effect in the absence of an antibacterial effect. This study demonstrates the importance for establishing microbial contamination standards for shellfish growing waters in the tropics based upon in situ studies with tropical species, e.g. mangrove oyster.

  17. Drum Involved in Idaho Incident Not Shippable to WIPP

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Venting prevents this hydrogen buildup while the drum is being handled and transported. The Advanced -More- -2- Mixed Waste Treatment Facility routinely processes drums that have ...

  18. Command and Control during Security Incidents/Emergencies

    SciTech Connect (OSTI)

    Knipper, W.

    2013-10-16

    This presentation builds on our response to events that pose, or have the potential to pose, a serious security or law enforcement risk and must be responded to and controlled in a clear a decisive fashion. We will examine some common concepts in the command and control of security-centric events.

  19. Best Practices for Emergency Response to Incidents Involving...

    Broader source: Energy.gov (indexed) [DOE]

    U.S.A. 02169-7471 E-MAIL: Foundation@NFPA.org WEB: www.nfpa.orgFoundation -- Page ... 8.2.5 Fires Involving Charging Stations 199 8.2.6 Overhaul and Recovery 199 9 ...

  20. Fuel Tax Incidence in Developing Countries: The Case of Costa...

    Open Energy Info (EERE)

    Conventional Energy Topics Finance, Market analysis, Background analysis Resource Type Lessons learnedbest practices Website http:www.rff.orgRFFDocumen Country Costa Rica...

  1. Integrated Approach to Documenting Readiness for a Potential Criticality Incident

    SciTech Connect (OSTI)

    Carlisle, Bruce S.; Prichard, Andrew W.; Jones, Robert A.

    2013-11-11

    There have been 60 highly publicized criticality accidents1 over the last 60 years and the nature of the hazard is unique. Recent studies2 discuss the benefits of knowing what to expect during and immediately following these events. Emergency planning and response standards2 provide an effective tool for establishing an adequate level of readiness to a criticality accident. While these planning requirements cover a broad spectrum of activities to establish readiness, a concise and routinely reviewed criticality accident scenario may be the most valuable tool in developing a cohesive understanding and response to these challenging events. Using a guideline3 for criticality safety evaluations the analytical work and emergency planning to mitigate a criticality accident at the Radiochemical Processing Laboratory at the Pacific Northwest National Laboratory, was developed. Using a single document the analysis that established the accident characteristics, response scenario based on emergency staffing and planning, and anticipated dose consequences were integrated. This single document approach provides a useful platform to integrate the initial planning and guide the review of proposed changes to emergency response plans.

  2. The National Traffic Safety Summit Traffic Incident Management...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and Mapping ) Deputy Sean Alexander, Houston County Sheriff's Office, (Metro Atlanta, GA) 1030 to 1200 Criminalistics: Using Crime Labs in your Investigations (Evidence ...

  3. Breached cylinder incident at the Portsmouth gaseous diffusion plant

    SciTech Connect (OSTI)

    Boelens, R.A.

    1991-12-31

    On June 16, 1990, during an inspection of valves on partially depleted product storage cylinders, a 14-ton partially depleted product cylinder was discovered breached. The cylinder had been placed in long-term storage in 1977 on the top row of Portsmouth`s (two rows high) storage area. The breach was observed when an inspector noticed a pile of green material along side of the cylinder. The breach was estimated to be approximately 8- inches wide and 16-inches long, and ran under the first stiffening ring of the cylinder. During the continuing inspection of the storage area, a second 14-ton product cylinder was discovered breached. This cylinder was stacked on the bottom row in the storage area in 1986. This breach was also located adjacent to a stiffening ring. This paper will discuss the contributing factors of the breaching of the cylinders, the immediate response, subsequent actions in support of the investigation, and corrective actions.

  4. Normal incidence X-ray mirror for chemical microanalysis

    DOE Patents [OSTI]

    Carr, Martin J.; Romig, Jr., Alton D.

    1990-01-01

    A non-planar, focusing mirror, to be utilized in both electron column instruments and micro-x-ray fluorescence instruments for performing chemical microanalysis on a sample, comprises a concave, generally spherical base substrate and a predetermined number of alternating layers of high atomic number material and low atomic number material contiguously formed on the base substrate. The thickness of each layer is an integral multiple of the wavelength being reflected and may vary non-uniformly according to a predetermined design. The chemical analytical instruments in which the mirror is used also include a predetermined energy source for directing energy onto the sample and a detector for receiving and detecting the x-rays emitted from the sample; the non-planar mirror is located between the sample and detector and collects the x-rays emitted from the sample at a large solid angle and focuses the collected x-rays to the sample. For electron column instruments, the wavelengths of interest lie above 1.5 nm, while for x-ray fluorescence instruments, the range of interest is below 0.2 nm. Also, x-ray fluorescence instruments include an additional non-planar focusing mirror, formed in the same manner as the previously described m The invention described herein was made in the performance of work under contract with the Department of Energy, Contract No. DE-AC04-76DP00789, and the United States Government has rights in the invention pursuant to this contract.

  5. The Medical Aspects of Radiation Incidents, 3rd Edition

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... Organ dose reference point 50 rem (committed) Approaches to Medical Management Medical management is specific and isotope-dependent; therefore identifying the isotope is crucial. ...

  6. Research Project on CO2 Geological Storage and Groundwater Resources: Water Quality Effects Caused by CO2 Intrusion into Shallow Groundwater

    SciTech Connect (OSTI)

    Birkholzer, Jens; Apps, John; Zheng, Liange; Zhang, Yingqi; Xu, Tianfu; Tsang, Chin-Fu

    2008-10-01

    One promising approach to reduce greenhouse gas emissions is injecting CO{sub 2} into suitable geologic formations, typically depleted oil/gas reservoirs or saline formations at depth larger than 800 m. Proper site selection and management of CO{sub 2} storage projects will ensure that the risks to human health and the environment are low. However, a risk remains that CO{sub 2} could migrate from a deep storage formation, e.g. via local high-permeability pathways such as permeable faults or degraded wells, and arrive in shallow groundwater resources. The ingress of CO{sub 2} is by itself not typically a concern to the water quality of an underground source of drinking water (USDW), but it will change the geochemical conditions in the aquifer and will cause secondary effects mainly induced by changes in pH, in particular the mobilization of hazardous inorganic constituents present in the aquifer minerals. Identification and assessment of these potential effects is necessary to analyze risks associated with geologic sequestration of CO{sub 2}. This report describes a systematic evaluation of the possible water quality changes in response to CO{sub 2} intrusion into aquifers currently used as sources of potable water in the United States. Our goal was to develop a general understanding of the potential vulnerability of United States potable groundwater resources in the event of CO{sub 2} leakage. This goal was achieved in two main tasks, the first to develop a comprehensive geochemical model representing typical conditions in many freshwater aquifers (Section 3), the second to conduct a systematic reactive-transport modeling study to quantify the effect of CO{sub 2} intrusion into shallow aquifers (Section 4). Via reactive-transport modeling, the amount of hazardous constituents potentially mobilized by the ingress of CO{sub 2} was determined, the fate and migration of these constituents in the groundwater was predicted, and the likelihood that drinking water

  7. Consortium for Advanced Simulation of Light Water Reactors

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Departure from nucleate boiling (DNB) serves as a critical pa- rameter in nuclear power plant operational and safety analysis. It occurs when a fuel rod clad surface is overheated due to the formation of a local vapor layer on the waterside surface, caus- ing a dramatic reduction in heat transfer capability. DNB is a complex phenomenon that has been experimentally and analyti- cally investigated over the past several decades. Its complexity is inherent in the multi-scale and multi-physics

  8. Released: September, 2008

    U.S. Energy Information Administration (EIA) Indexed Site

    E3A. Electricity Consumption (Btu) by End Use for All Buildings, 2003" ,"Total Electricity Consumption (trillion Btu)" ,"Total ","Space Heat- ing","Cool- ing","Venti-...

  9. Released: September, 2008

    U.S. Energy Information Administration (EIA) Indexed Site

    . Electricity Consumption (Btu) by End Use for Non-Mall Buildings, 2003" ,"Total Electricity Consumption (trillion Btu)" ,"Total ","Space Heat- ing","Cool- ing","Venti-...

  10. --No Title--

    Gasoline and Diesel Fuel Update (EIA)

    (trillion Btu) District Heat Energy Intensity (thousand Btusquare foot) Total Space Heating Water Heating Cook- ing Other Total Space Heating Water Heating Cook- ing Other All...

  11. Total Space Heating Water Heating Cook-

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    Commercial Buildings Energy Consumption Survey: Energy End-Use Consumption Tables Total Space Heating Water Heating Cook- ing Other Total Space Heating Water Heating Cook- ing...

  12. --No Title--

    Gasoline and Diesel Fuel Update (EIA)

    (billion cubic feet) Natural Gas Energy Intensity (cubic feetsquare foot) Total Space Heating Water Heating Cook- ing Other Total Space Heating Water Heating Cook- ing...

  13. --No Title--

    Gasoline and Diesel Fuel Update (EIA)

    (trillion Btu) Natural Gas Energy Intensity (thousand Btusquare foot) Total Space Heating Water Heating Cook- ing Other Total Space Heating Water Heating Cook- ing...

  14. U.S. Department of Energy

    Office of Scientific and Technical Information (OSTI)

    ... than an HRP-certified individual is not ing: ing HRP duties is denied both escorted and ... Contractor means subcontractors at all tiers and any industrial, educational, commercial, ...

  15. --No Title--

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    E4A. Electricity Consumption (Btu) Intensities by End Use for All Buildings, 2003 Electricity Energy Intensity (thousand Btusquare foot) Total Space Heat- ing Cool- ing Venti-...

  16. --No Title--

    Gasoline and Diesel Fuel Update (EIA)

    E4. Electricity Consumption (Btu) Intensities by End Use for Non-Mall Buildings, 2003 Electricity Energy Intensity (thousand Btusquare foot) Total Space Heat- ing Cool- ing Venti-...

  17. --No Title--

    Gasoline and Diesel Fuel Update (EIA)

    (million gallons) Fuel Oil Energy Intensity (gallonssquare foot) Total Space Heating Water Heating Cook- ing Other Total Space Heating Water Heating Cook- ing Other All...

  18. --No Title--

    Gasoline and Diesel Fuel Update (EIA)

    Btu) District Heat Energy Intensity (thousand Btusquare foot) Total Space Heating Water Heating Cook- ing Other Total Space Heating Water Heating Cook- ing Other All...

  19. --No Title--

    Gasoline and Diesel Fuel Update (EIA)

    Btu) Natural Gas Energy Intensity (thousand Btusquare foot) Total Space Heating Water Heating Cook- ing Other Total Space Heating Water Heating Cook- ing Other All...

  20. --No Title--

    Gasoline and Diesel Fuel Update (EIA)

    cubic feet) Natural Gas Energy Intensity (cubic feetsquare foot) Total Space Heating Water Heating Cook- ing Other Total Space Heating Water Heating Cook- ing Other All...

  1. Total Space Heating Water Heating Cook-

    Gasoline and Diesel Fuel Update (EIA)

    Released: September, 2008 Total Space Heating Water Heating Cook- ing Other Total Space Heating Water Heating Cook- ing Other All Buildings* ... 1,870 1,276...

  2. --No Title--

    Gasoline and Diesel Fuel Update (EIA)

    (trillion Btu) Fuel Oil Energy Intensity (thousand Btusquare foot) Total Space Heating Water Heating Cook- ing Other Total Space Heating Water Heating Cook- ing Other All...

  3. Total Space Heating Water Heating Cook-

    Gasoline and Diesel Fuel Update (EIA)

    Energy Consumption Survey: Energy End-Use Consumption Tables Total Space Heating Water Heating Cook- ing Other Total Space Heating Water Heating Cook- ing Other All...

  4. Total Space Heating Water Heating Cook-

    Gasoline and Diesel Fuel Update (EIA)

    Released: September, 2008 Total Space Heating Water Heating Cook- ing Other Total Space Heating Water Heating Cook- ing Other All Buildings* ... 1,602 1,397...

  5. Total Space Heating Water Heating Cook-

    Gasoline and Diesel Fuel Update (EIA)

    Released: September, 2008 Total Space Heating Water Heating Cook- ing Other Total Space Heating Water Heating Cook- ing Other All Buildings ... 2,037...

  6. --No Title--

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    A. Major Fuel Consumption (Btu) Intensities by End Use for All Buildings, 2003 Major Fuel Energy Intensity (thousand Btusquare foot) Total Space Heat- ing Cool- ing Venti- lation...

  7. Released: June 2006

    U.S. Energy Information Administration (EIA) Indexed Site

    2. Water Heating Equipment, Number of Buildings and Floorspace for Non-Mall Buildings, ... ,"All Build- ings*","Build- ings with Water Heating","Type of Water Heating ...

  8. Revised: December, 2008

    U.S. Energy Information Administration (EIA) Indexed Site

    by End Use for All Buildings, 2003" ," Major Fuel Energy Intensity (thousand Btusquare foot) " ,"Total ","Space Heat- ing","Cool- ing","Venti- lation","Water Heat-...

  9. Can Asteroid Airbursts Cause Dangerous Tsunami?.

    SciTech Connect (OSTI)

    Boslough, Mark B.

    2015-10-01

    I have performed a series of high-resolution hydrocode simulations to generate “source functions” for tsunami simulations as part of a proof-of-principle effort to determine whether or not the downward momentum from an asteroid airburst can couple energy into a dangerous tsunami in deep water. My new CTH simulations show enhanced momentum multiplication relative to a nuclear explosion of the same yield. Extensive sensitivity and convergence analyses demonstrate that results are robust and repeatable for simulations with sufficiently high resolution using adaptive mesh refinement. I have provided surface overpressure and wind velocity fields to tsunami modelers to use as time-dependent boundary conditions and to test the hypothesis that this mechanism can enhance the strength of the resulting shallow-water wave. The enhanced momentum result suggests that coupling from an over-water plume-forming airburst could be a more efficient tsunami source mechanism than a collapsing impact cavity or direct air blast alone, but not necessarily due to the originally-proposed mechanism. This result has significant implications for asteroid impact risk assessment and airburst-generated tsunami will be the focus of a NASA-sponsored workshop at the Ames Research Center next summer, with follow-on funding expected.

  10. DIRECT COSTS OF DISABLING WORKPLACE INJURIES GROW 2.5 PERCENT

    Broader source: Energy.gov [DOE]

    April 7, 2003 Annual Liberty Mutual Workplace Safety Index Shows Direct Costs of the Three Leading Causes of Workplace Incidents Grew Significantly Faster...

  11. U.S. Energy Information Administration (EIA)

    Gasoline and Diesel Fuel Update (EIA)

    include, among other things, pipeline breaks caused by digging equipment, metal corrosion, and equipment failure. PHMSA classified 66% of these incidents as "significant" and...

  12. Healthcare Energy Impact Calculator | Open Energy Information

    Open Energy Info (EERE)

    is an online tool that estimates the number and costs of premature deaths and other health-related incidents caused by operation emissions in healthcare facilities. LEDSGP green...

  13. QA Standard Contract Language

    Office of Environmental Management (EM)

    Energy FORGE-ing Ahead to Clean, Low-Cost Geothermal Energy Q&A: FORGE-ing Ahead to Clean, Low-Cost Geothermal Energy July 17, 2014 - 2:48pm Addthis Q&A: FORGE-ing Ahead to Clean, Low-Cost Geothermal Energy Q&A: FORGE-ing Ahead to Clean, Low-Cost Geothermal Energy Q&A: FORGE-ing Ahead to Clean, Low-Cost Geothermal Energy Q&A: FORGE-ing Ahead to Clean, Low-Cost Geothermal Energy Lauren Boyd Lauren Boyd Program Manager, Enhanced Geothermal Systems (EGS) Benjamin Phillips

  14. Q-weak Experiment Determines Proton's Weak Charge | U.S. DOE Office of

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Energy FORGE-ing Ahead to Clean, Low-Cost Geothermal Energy Q&A: FORGE-ing Ahead to Clean, Low-Cost Geothermal Energy July 17, 2014 - 2:48pm Addthis Q&A: FORGE-ing Ahead to Clean, Low-Cost Geothermal Energy Q&A: FORGE-ing Ahead to Clean, Low-Cost Geothermal Energy Q&A: FORGE-ing Ahead to Clean, Low-Cost Geothermal Energy Q&A: FORGE-ing Ahead to Clean, Low-Cost Geothermal Energy Lauren Boyd Lauren Boyd Program Manager, Enhanced Geothermal Systems (EGS) Benjamin Phillips

  15. Overseas shipments of 48Y cylinders

    SciTech Connect (OSTI)

    Tanaka, R.T.; Furlan, A.S.

    1991-12-31

    This paper describes experiences with two incidents of overseas shipments of uranium hexafluoride (UF{sub 6}) cylinders. The first incident involved nine empty UF{sub 6} cylinders in enclosed sea containers. Three UF{sub 6} cylinders broke free from their tie-downs and damaged and contaminated several sea containers. This paper describes briefly how decontamination was carried out. The second incident involved a shipment of 14 full UF{sub 6} cylinders. Although the incident did not cause an accident, the potential hazard was significant. The investigation of the cause of the near accident is recounted. Recommendations to alleviate future similar incidents for both cases are presented.

  16. Released: September, 2008

    U.S. Energy Information Administration (EIA) Indexed Site

    A. Electricity Consumption (kWh) Intensities by End Use for All Buildings, 2003" ,"Electricity Energy Intensity (kWhsquare foot)" ,"Total ","Space Heat- ing","Cool- ing","Venti-...

  17. Released: September, 2008

    U.S. Energy Information Administration (EIA) Indexed Site

    . Electricity Consumption (kWh) by End Use for Non-Mall Buildings, 2003" ,"Total Electricity Consumption (billion kWh)" ,"Total ","Space Heat- ing","Cool- ing","Venti-...

  18. Released: September, 2008

    U.S. Energy Information Administration (EIA) Indexed Site

    A. Electricity Consumption (kWh) by End Use for All Buildings, 2003" ,"Total Electricity Consumption (billion kWh)" ,"Total ","Space Heat- ing","Cool- ing","Venti- lation","Water...

  19. Total Space Heating Water Heating Cook-

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    Tables Total Space Heating Water Heating Cook- ing Other Total Space Heating Water Heating Cook- ing Other All Buildings* ... 634 578 46 1 Q 116.4 106.3...

  20. --No Title--

    Gasoline and Diesel Fuel Update (EIA)

    . Electricity Consumption (kWh) Intensities by End Use for Non-Mall Buildings, 2003 Electricity Energy Intensity (kWhsquare foot) Total Space Heat- ing Cool- ing Venti- lation...

  1. Impact of Infiltration and Ventilation on Measured Space Conditioning...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Dur- ing cooler weather when the air conditioner is not running, lower air exchange levels can ... Test- ing suggested that "smart" ventilation control systems may be able to provide ...

  2. Browse by Discipline -- E-print Network Subject Pathways: Computer...

    Office of Scientific and Technical Information (OSTI)

    ... Ulm, Universitt - Fakultt fr Mathematik und Wirtschaftswissenschaften Universidad de la Repblica, Instituto de Matemtica y Estadstica "Prof. Ing. Rafael Laguardia" ...

  3. Biomass Feedstock Supply Modeling

    Broader source: Energy.gov (indexed) [DOE]

    ... C CO Buf f er C CO Pelletizer 010 R Q Pump SP CO S0 Mov ing pellets C CO Pellet storage C ... R Q Pump C CO Pelletizer SP CO S0 Mov ing pellets C CO Pellet storage SP CO S0 Mov ing to ...

  4. Taxonomies of Cyber Adversaries and Attacks: A Survey of Incidents and Approaches

    SciTech Connect (OSTI)

    Meyers, C A; Powers, S S; Faissol, D M

    2009-10-08

    In this paper we construct taxonomies of cyber adversaries and methods of attack, drawing from a survey of the literature in the area of cyber crime. We begin by addressing the scope of cyber crime, noting its prevalence and effects on the US economy. We then survey the literature on cyber adversaries, presenting a taxonomy of the different types of adversaries and their corresponding methods, motivations, maliciousness, and skill levels. Subsequently we survey the literature on cyber attacks, giving a taxonomy of the different classes of attacks, subtypes, and threat descriptions. The goal of this paper is to inform future studies of cyber security on the shape and characteristics of the risk space and its associated adversaries.

  5. Edge effects, not connectivity, determine the incidence and development of a foliar fungal plant disease.

    SciTech Connect (OSTI)

    Johnson, Brenda, L.; Haddad, Nick, M.

    2011-08-01

    Using a model plant-pathogen system in a large-scale habitat corridor experiment, we found that corridors do not facilitate the movement of wind-dispersed plant pathogens, that connectivity of patches does not enhance levels of foliar fungal plant disease, and that edge effects are the key drivers of plant disease dynamics. Increased spread of infectious disease is often cited as a potential negative effect of habitat corridors used in conservation, but the impacts of corridors on pathogen movement have never been tested empirically. Using sweet corn (Zea mays) and southern corn leaf blight (Cochliobolus heterostrophus) as a model plant-pathogen system, we tested the impacts of connectivity and habitat fragmentation on pathogen movement and disease development at the Savannah River Site, South Carolina, USA. Over time, less edgy patches had higher proportions of diseased plants, and distance of host plants to habitat edges was the greatest determinant of disease development. Variation in average daytime temperatures provided a possible mechanism for these disease patterns. Our results show that worries over the potentially harmful effects of conservation corridors on disease dynamics are misplaced, and that, in a conservation context, many diseases can be better managed by mitigating edge effects.

  6. Metrology for Industry for use in the Manufacture of Grazing Incidence Beam Line Mirrors

    SciTech Connect (OSTI)

    Metz, James P.; Parks, Robert E.

    2014-12-01

    The goal of this SBIR was to determine the slope sensitivity of Specular Reflection Deflectometry (SRD) and whether shearing methods had the sensitivity to be able to separate errors in the test equipment from slope error in the unit under test (UUT), or mirror. After many variations of test parameters it does not appear that SRD yields results much better than 1 μ radian RMS independent of how much averaging is done. Of course, a single number slope sensitivity over the full range of spatial scales is not a very insightful number in the same sense as a single number phase or height RMS value in interferometry does not tell the full story. However, the 1 μ radian RMS number is meaningful when contrasted with a sensitivity goal of better than 0.1 μ radian RMS. Shearing is a time proven method of separating the errors in a measurement from the actual shape of a UUT. It is accomplished by taking multiple measurements while moving the UUT relative to the test instrument. This process makes it possible to separate the two errors sources but only to a sensitivity of about 1 μ radian RMS. Another aspect of our conclusions is that this limit probably holds largely independent of the spatial scale of the test equipment. In the proposal for this work it was suggested that a test screen the full size of the UUT could be used to determine the slopes on scales of maybe 0.01 to full scale of the UUT while smaller screens and shorter focal length lenses could be used to measure shorter, or smaller, patches of slope. What we failed to take into consideration was that as the scale of the test equipment got smaller so too did the optical lever arm on which the slope was calculated. Although we did not do a test with a shorter focal length lens over a smaller sample area it is hard to argue with the logic that the slope sensitivity will be about the same independent of the spatial scale of the measurement assuming the test equipment is similarly scaled. On a more positive note, SRD does appear to be a highly flexible, easy to implement, rather inexpensive test for free form optics that require a dynamic range that exceeds that of interferometry. These optics are quite often specified to have more relaxed slope errors, on the order of 1 μ radian RMS or greater. It would be shortsighted to not recognize the value of this test method in the bigger picture.

  7. In Situ Grazing-Incidence Extended X-ray Absorption Fine Structure...

    Office of Scientific and Technical Information (OSTI)

    oxides. Authors: Bargar, John ; Trainor, T P. ; Fitts, J P. ; Chambers, Scott A. ; Brown, Gordon E. Publication Date: 2004-03-02 OSTI Identifier: 15007114 Report Number(s):...

  8. X-ray imaging with grazing-incidence microscopes developed for...

    Office of Scientific and Technical Information (OSTI)

    on the Ligne d'Integration Laser (LIL) facility J. P. Le Breton et al., Inertial Fusion Sciences and Applications 2001 (Elsevier, Paris, 2002), pp. 856-862 (24 kJ, UV--0.35 nm). ...

  9. THE INCIDENCE OF ACTIVE GALACTIC NUCLEI IN PURE DISK GALAXIES: THE SPITZER VIEW

    SciTech Connect (OSTI)

    Satyapal, S.; Mcalpine, W.; Gliozzi, M. [George Mason University, Department of Physics and Astronomy, MS 3F3, 4400 University Drive, Fairfax, VA 22030 (United States); Boeker, T. [ESA/ESTEC, Keplerlaan 1, 2200 AG Noordwijk (Netherlands); Abel, N. P. [Department of Physics, University of Cincinnati, Cincinnati, OH 45221 (United States); Heckman, T., E-mail: satyapal@physics.gmu.ed [Center for Astrophysical Sciences, Department of Physics and Astronomy, Johns Hopkins University, Baltimore, MD 21218 (United States)

    2009-10-10

    Using the Spitzer telescope, we have conducted a high-resolution spectroscopic study of 18 bulgeless (Hubble type of Sd or Sdm) galaxies that show no definitive signatures of nuclear activity in their optical spectra. This is the first systematic mid-infrared (MIR) search for weak or hidden active galactic nuclei (AGNs) in a statistically significant sample of bulgeless (Sd/Sdm) disk galaxies. Based on the detection of the high-ionization [Ne V] 14.3 mum line, we report the discovery of an AGN in 1 out of the 18 galaxies in the sample. This galaxy, NGC 4178, is a nearby edge-on Sd galaxy, which likely hosts a prominent nuclear star cluster (NSC). The bolometric luminosity of the AGN inferred from the [Ne V] line luminosity is approx8 x 10{sup 41} ergs s{sup -1}. This is almost 2 orders of magnitude greater than the luminosity of the AGN in NGC 4395, the best studied AGN in a bulgeless disk galaxy. Assuming that the AGN in NGC 4178 is radiating below the Eddington limit, the lower mass limit for the black hole is approx6 x 10{sup 3} M {sub sun}. The fact that none of the other galaxies in the sample shows any evidence for an AGN demonstrates that while the AGN detection rate based on MIR diagnostics is high (30%-40%) in optically quiescent galaxies with pseudobulges or weak classical bulges (Hubble type Sbc and Sc), it drops drastically in Sd/Sdm galaxies. Our observations, therefore, confirm that AGNs in completely bulgeless disk galaxies are not hidden in the optical but truly are rare. Of the three Sd galaxies with AGNs known so far, all have prominent NSCs, suggesting that in the absence of a well-defined bulge, the galaxy must possess an NSC in order to host an AGN. On the other hand, while the presence of an NSC appears to be a requirement for hosting an AGN in bulgeless galaxies, neither the properties of the NSC nor those of the host galaxy appear exceptional in late-type AGN host galaxies. The recipe for forming and growing a central black hole in a bulgeless galaxy therefore remains unknown.

  10. A high incidence of BRCA1 mutations in 20 breast-ovarian cancer families

    SciTech Connect (OSTI)

    Serova, O.; Montagna, M.; Sylla, B.

    1996-01-01

    We have analyzed 20 breast-ovarian cancer families, the majority of which show positive evidence of linkage to chromosome 17q12, for germ-line mutations in the BRCA1 gene. BRCA1 mutations cosegregating with breast and ovarian cancer susceptibility were identified in 16 families, including 1 family with a case of male breast cancer. Nine of these mutations have not been reported previously. The majority of mutations were found to generate a premature stop codon leading to the formation of a truncated BRCA1 protein of 2%-88% of the expected normal length. Two mutations altered the RING finger domain. Sequencing of genomic DNA led to the identification of a mutation in the coding region of BRCA1 in 12 families, and cDNA analysis revealed an abnormal or missing BRCA1 transcript in 4 of the 8 remaining families. A total of eight mutations were associated with a reduced quantity of BRCA1 transcript. We were unable to detect BRCA1 mutations in 4 of the 20 families, but only 1 of these was clearly linked to BRCA1. It is expected that the majority of clear examples of the breast-ovarian cancer syndrome will be associated with germ-line mutations in the coding region of BRCA1. 30 refs., 4 figs., 3 tabs.

  11. Head of EM Visits Waste Isolation Pilot Plant for First Underground Tour Since February Incidents

    Broader source: Energy.gov [DOE]

    CARLBAD, N.M. – EM Acting Assistant Secretary Mark Whitney today visited the Waste Isolation Pilot Plant (WIPP) near Carlsbad, N.M., where he became the first non-WIPP employee to tour the underground facility since a truck fire and unrelated radiological release temporarily closed the facility in February.

  12. Laser warning receiver to identify the wavelength and angle of arrival of incident laser light

    DOE Patents [OSTI]

    Sinclair; Michael B.; Sweatt, William C.

    2010-03-23

    A laser warning receiver is disclosed which has up to hundreds of individual optical channels each optically oriented to receive laser light from a different angle of arrival. Each optical channel has an optical wedge to define the angle of arrival, and a lens to focus the laser light onto a multi-wavelength photodetector for that channel. Each multi-wavelength photodetector has a number of semiconductor layers which are located in a multi-dielectric stack that concentrates the laser light into one of the semiconductor layers according to wavelength. An electrical signal from the multi-wavelength photodetector can be processed to determine both the angle of arrival and the wavelength of the laser light.

  13. Recovery from a chemical weapons accident or incident: A concept paper on planning

    SciTech Connect (OSTI)

    Herzenberg, C.L.; Haffenden, R.; Lerner, K.; Meleski, S.A.; Tanzman, E.A.; Lewis, L.M.; Hemphill, R.C.; Adams, J.D.

    1994-04-01

    Emergency planning for an unintended release of chemical agent from the nation`s chemical weapons stockpile should include preparation for. the period following implementation of immediate emergency response. That period -- the recovery, reentry, and restoration stage -- is the subject of this report. The report provides an overview of the role of recovery, reentry, and restoration planning in the Chemical Stockpile Emergency Preparedness Program (CSEPP), describes the transition from immediate emergency response to restoration, and analyzes the legal framework that would govern restoration activities. Social, economic, and administrative issues, as well as technical ones, need to be considered in the planning effort. Because of possible jurisdictional conflicts, appropriate federal, state, and local agencies need to be included in a coordinated planning process. Advance consideration should be given to the pertinent federal and state statutes and regulations. On the federal level, the principal statutes and regulations to be considered are those associated with the Comprehensive Environmental Response, Compensation, and Liability Act; the Resource Conservation and Recovery Act; and the National Environmental Policy Act. This report recommends that extensive preaccident planning be undertaken for the recovery, reentry, and restoration stage and outlines several key issues that should be considered in that planning. The need for interagency cooperation and coordination at all levels of the planning process is emphasized.

  14. Decontamination and Management of Human Remains Following Incidents of Hazardous Chemical Release

    SciTech Connect (OSTI)

    Hauschild, Veronique; Watson, Annetta Paule; Bock, Robert Eldon

    2012-01-01

    Abstract Objective: To provide specific procedural guidance and resources for identification, assessment, control, and mitigation of compounds that may contaminate human remains resulting from chemical attack or release. Design: A detailed technical, policy, and regulatory review is summarized. Setting: Guidance is suitable for civilian or military settings where human remains potentially contaminated with hazardous chemicals may be present. Settings would include sites of transportation accidents, natural disasters, terrorist or military operations, mortuary affairs or medical examiner processing and decontamination points, and similar. Patients, Participants: While recommended procedures have not been validated with actual human remains, guidance has been developed from data characterizing controlled experiments with fabrics, materiel, and laboratory animals. Main Outcome Measure(s): Presentation of logic and specific procedures for remains management, protection and decontamination of mortuary affairs personnel, as well as decision criteria for determining when remains are sufficiently decontaminated so as to pose no chemical health hazard. Results: Established procedures and existing equipment/materiel available for decontamination and verification provide appropriate and reasonable means to mitigate chemical hazards from remains. Extensive characterization of issues related to remains decontamination indicates that supra-lethal concentrations of liquid chemical warfare agent VX may prove difficult to decontaminate and verify in a timely fashion. Specialized personnel can and should be called upon to assist with monitoring necessary to clear decontaminated remains for transport and processing. Conclusions: Once appropriate decontamination and verification have been accomplished, normal procedures for remains processing and transport to the decedent s family and the continental United States can be followed.

  15. Biological Monitoring at Amchitka Appears to Show Impacts from Fukushima Dai-ichi Incident

    Broader source: Energy.gov [DOE]

    The U.S. Department of Energy Office Legacy Management (LM) has a long-term stewardship mission to protect human health and the environment from the legacy of underground nuclear testing conducted at Amchitka Island, Alaska, from 1965 to 1971.

  16. Environmental Remediation Activities in Japan Following the Fukushima Dai-ichi Reactor Incident - 12603

    SciTech Connect (OSTI)

    Lively, J.W.; Kelley, J.L.; Marcial, M.R.; Yashio, Shoko; Kuriu, Nobou; Kamijo, Hiroaki; Jotatsu, Kato

    2012-07-01

    In March 2011, the Fukushima Dai-ichi reactor power plant was crippled by the Great Pacific earthquake and subsequent tsunami. Much of the focus in the news was on the reactor site itself as the utility company (TEPCO), the Japanese government, and experts from around the world worked to bring the damaged plants into a safe shutdown condition and stem the release of radioactivity to the environment. Most of the radioactivity released was carried out to sea with the prevailing winds. Still, as weather patterns changed and winds shifted, a significant plume of radioactive materials released from the plant deposited in the environment surrounding the plant, contaminating large land areas of the Fukushima Prefecture. The magnitude of the radiological impact to the surrounding environmental is so large that the Japanese government has had to reevaluate the meaning of 'acceptably clean'. In many respects, 'acceptably clean' cannot be a one-size-fits-all standard. The economics costs of such an approach would make impossible what is already an enormous and costly environmental response and remediation task. Thus, the Japanese government has embarked upon an approach that is both situation-specific and reasonably achievable. For example, the determination of acceptably clean for a nursery school or kindergarten play yard may be different from that for a parking lot. The acceptably clean level of residual radioactivity in the surface soil of a rice paddy is different from that in a forested area. The recognized exposure situation (scenario) thus plays a large role in the decision process. While sometimes complicated to grasp or implement, such an approach does prioritize national resources to address environment remediation based upon immediate and significant risks. In addition, the Japanese government is testing means and methods, including advanced or promising technologies, that could be proven to be effective in reducing the amount of radioactivity in the environment beyond a fixed, concentration based limit. Essentially, the definition of acceptably clean includes the concept of reasonably achievable, given the available technology, means and methods, and the cost to implement such. The Japanese government recently issued three technology demonstration contracts expressly designed to test and evaluate the available technologies, means, and methods, which, if implemented, might produce the greatest risk reduction from environmental contamination for the best value. One of the Japanese contract holders, Obayashi JV, has teamed with AMEC to demonstrate the applicability and capabilities of the Orion ScanPlot{sup SM} and ScanSort{sup SM} technologies in radiologically impacted towns both inside and immediately outside the 20 km restricted zone. This presentation provides some unique images and informative insight into the environmental radioactive impacts in and around the exclusion zone. It will provide a look at one element of the Japanese government?s efforts to achieve the greatest risk reduction that is reasonably achievable. The Orion ScanPlot{sup SM} and ScanSort{sup SM} are being used with success on the Japan Town Demonstration Project to assess pre-remedial action contamination levels, document the post-remedial action contamination levels and to precisely measure and segregate excavated soils based on their radioactive content and the prescribed segregation limits (DCS). Initial results suggest that these technologies could provide capabilities to the remedial action efforts that would result in considerable improvements in field data certainty and compliance with remedial objectives while reducing overall costs. (authors)

  17. Exposure Levels for Chemical Threat Compounds; Information to Facilitate Chemical Incident Response

    SciTech Connect (OSTI)

    Hauschild, Veronique; Watson, Annetta Paule

    2013-01-01

    Exposure Standards, Limits and Guidelines for Chemical Threat Compunds ABSTRACT Exposure criteria for chemical warfare (CW) agents and certain toxic industrial chemicals (TICs) used as CW agents (such as chlorine fill in an improvised explosive device) have been developed for protection of the civilian general public, civilian employees in chemical agent processing facilities and deployed military populations. In addition, compound-specific concentrations have been developed to serve as how clean is clean enough clearance criteria guiding facility recovery following chemical terrorist or other hazardous release events. Such criteria are also useful to verify compound absence, identify containment boundaries and expedite facility recovery following chemical threat release. There is no single right value or concentration appropriate for all chemical hazard control applications. It is acknowledged that locating and comparing the many sources of CW agent and TIC exposure criteria has not been previously well-defined. This paper summarizes many of these estimates and assembles critical documentation regarding their derivation and use.

  18. Azimuthal anisotropy of the scattered radiation in grazing incidence X-ray fluorescence

    SciTech Connect (OSTI)

    Das, Gangadhar Tiwari, M. K.; Singh, A. K.; Ghosh, Haranath

    2015-06-24

    The Compton and elastic scattering radiations are the major contributor to the spectral background of an x-ray fluorescence spectrum, which eventually limits the element detection sensitivities of the technique to µg/g (ppm) range. In the present work, we provide a detail mathematical descriptions and show that how polarization properties of the synchrotron radiation influence the spectral background in the x-ray fluorescence technique. We demonstrate our theoretical understandings through experimental observations using total x-ray fluorescence measurements on standard reference materials. Interestingly, the azimuthal anisotropy of the scattered radiation is shown to have a vital role on the significance of the x-ray fluorescence detection sensitivities.

  19. EARTHQUAKE CAUSED RELEASES FROM A NUCLEAR FUEL CYCLE FACILITY

    SciTech Connect (OSTI)

    Charles W. Solbrig; Chad Pope; Jason Andrus

    2014-08-01

    The fuel cycle facility (FCF) at the Idaho National Laboratory is a nuclear facility which must be licensed in order to operate. A safety analysis is required for a license. This paper describes the analysis of the Design Basis Accident for this facility. This analysis involves a model of the transient behavior of the FCF inert atmosphere hot cell following an earthquake initiated breach of pipes passing through the cell boundary. The hot cell is used to process spent metallic nuclear fuel. Such breaches allow the introduction of air and subsequent burning of pyrophoric metals. The model predicts the pressure, temperature, volumetric releases, cell heat transfer, metal fuel combustion, heat generation rates, radiological releases and other quantities. The results show that releases from the cell are minimal and satisfactory for safety. This analysis method should be useful in other facilities that have potential for damage from an earthquake and could eliminate the need to back fit facilities with earthquake proof boundaries or lessen the cost of new facilities.

  20. COLLOQUIUM: Volcanism, Impacts and Mass Extinctions: Causes and...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    at PPPL, adult visitors must show a government-issued photo I.D. - for example, a passport or a driver's license. Non-U.S. citizens must show a government-issued photo I.D.,...

  1. Conductive Network and [beta] Polymorph Content Evolution Caused...

    Office of Scientific and Technical Information (OSTI)

    Country of Publication: United States Language: ENGLISH Word Cloud More Like This Full Text Journal Articles DOI: 10.1021acs.jpcc.6b01745 Select the DOI to obtain a copy of this ...

  2. Root Cause Analysis (RCA) & Corrective Action Plan (CAP)

    Broader source: Energy.gov [DOE]

    Improving the Department of Energy's project and contract management continues to be one of the Department's management priorities. Excellence in this area helps ensure that DOE's programs and...

  3. Role of shocks and mix caused by capsule defects

    SciTech Connect (OSTI)

    Bradley, P. A.; Cobble, J. A.; Tregillis, I. L.; Schmitt, M. J.; Obrey, K. D.; Batha, S. H.; Magelssen, G. R.; Fincke, J. R.; Hsu, S. C.; Krasheninnikova, N. S.; Murphy, T. J.; Wysocki, F. J.; Glebov, V.

    2012-09-15

    An Eulerian code with a turbulent mix model is used to model a set of plastic (CH) ablator capsules with and without equatorial grooves. The 'perfect' capsule results were used to calibrate simulations of capsules with equatorial grooves of different depths that provided information on increasingly perturbed implosions. Simulations with a turbulence model were able to calculate the same yield over mix (YOM) ratio (experiment/mix simulation) of 0.2 to 0.3 for thin (8-{mu}m thick) and thick shell (15-{mu}m thick) capsules with no grooves and thin capsules with shallow grooves. When the capsules have deep grooves, the YOM ratio increases to greater than unity, probably because the deformed shocks focus too strongly on the symmetry axis in our two-dimensional simulations. This is supported by a comparison of simulated and experimental x-ray images.

  4. On spectral perturbation caused by bounded variation of potential

    SciTech Connect (OSTI)

    Ismagilov, R S

    2014-01-31

    The harmonic oscillator operator is perturbed by an arbitrary bounded continuous term. This results in the perturbation of the spectrum. The map sending the first of these perturbations into the second is examined. Its approximation by a linear map is studied. Bibliography: 2 titles.

  5. Indoor radon and decay products: Concentrations, causes, and control strategies

    SciTech Connect (OSTI)

    Nero, A.V.; Gadgil, A.J.; Nazaroff, W.W.; Revzan, K.L.

    1990-11-01

    This report is another in the on going technical report series that addresses various aspects of the DOE Radon Research Program. It provides an overview of what is known about the behavior of radon and its decay products in the indoor environment and examines the manner in which several important classes of factors -- structural, geological, and meteorological -- affect indoor radon concentrations. Information on US indoor radon concentrations, currently available monitoring methods and novel radon control strategies are also explored. 238 refs., 22 figs., 9 tabs.

  6. U. S. oil spill law to cause growing tanker problem

    SciTech Connect (OSTI)

    Price, R.B.

    1991-09-30

    This paper reports on tanker owners which face a growing dilemma on the issue of oil spill liability. The U.S. Oil Pollution Act, passed last year in the wake of the March 1989 Exxon Valdez oil spill, was intended to reduce risk of and damage from such accidents. However, in addition to phasing in double hulls on most tankers operating in U.S. waters, the law substantially increases shipowner's liability for spills. And the federal law does not preempt state liability laws, which in most cases amount to unlimited liability for spill cleanup. Rather than face potentially unlimited liability in the event of a spill, tanker owners worldwide are exercising a number of options to shield themselves. Some of those options could increase the potential for oil spills, industry officials warn. The act also threatens to shatter the international alliance among shippers. A report by Drewry Shipping Consultants Ltd., London, says the law could have a devastating effect on operating practices. Tanker owners and operators have voiced the most opposition to the new spill law and the shackles it places on them. Now the industry that insures tankers has spoken up about is increased liability, and it too may launch a boycott.

  7. Ignoring mesophyll diffusion causes carbon cycle models to underestima...

    Office of Scientific and Technical Information (OSTI)

    ... achieved via a parameter conversion function that was ... Biomass carbon residence time will need to be considered as ... about key biochemical processes of photosynthesis (13-14). ...

  8. Decoherence and dephasing errors caused by the dc Stark effect...

    Office of Scientific and Technical Information (OSTI)

    Department of Physics, University of Toronto, 60 Saint George Street, Toronto, M5S 1A7 Ontario (Canada) Publication Date: 2011-06-15 OSTI Identifier: 21550080 Resource Type: ...

  9. What Causes Electron Heat Loss in Fusion Plasma?

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Can Solar Do for You What Can Solar Do for You October 28, 2014 - 1:28pm Addthis Solar energy benefits homeowners, the job market, and the planet. | Photo courtesy of Dennis Schroeder, National Renewable Energy Lab Solar energy benefits homeowners, the job market, and the planet. | Photo courtesy of Dennis Schroeder, National Renewable Energy Lab Paige Terlip Paige Terlip Former Communicator, National Renewable Energy Laboratory What does this mean for me? Using solar energy at home can help you

  10. After Kyoto, science still probes global warming causes

    SciTech Connect (OSTI)

    Westbrook, G.

    1998-01-19

    The Kyoto meeting has come and gone. In the US, the treaty still has to be signed by President Bill Clinton and ratified by the Senate, an action that is most unlikely in view of last year`s 95-0 vote on the issue. In the short term 36 senators are up for reelection in November and therefore likely to come under intense pressure to change their positions, to support the Kyoto treaty, and to push for Senate action. Senators will need support, additional inputs, and overall reinforcement of their positions. One area that this writer believes still has much to offer in this context is the quality--more specifically, the lack of quality--of much of the scientific evidence behind this treaty. Part of that subject is the natural variability in the climate. Natural climate variability is based on cyclical forces, random events, and the Earth`s response to these two factors. These forces create the variability in the climate, the background noise above which any signal of anthropogenic warming must rise in order to be detected. A review of key climatic cycles is the subject of this article.

  11. Galvanic currents and hydrogen permeation currents caused by galvanic coupling

    SciTech Connect (OSTI)

    Armacanquil, M.E. ); Harasyn, D.E. )

    1990-05-01

    This paper reports on galvanic coupling and hydrogen permeation experiments performed in a Devanathan-Stachurski cell to measure simultaneously the galvanic currents and the hydrogen permeation currents in an attempt to determine the extent of hydrogen charging into noble metals as a result of galvanic coupling. Large amounts of hydrogen permeated through the more noble element of the couple. The magnitude of the hydrogen permeation flux varied depending on the galvanic coupling conditions. No simple direct relationship between galvanic currents and hydrogen permeation currents was observed, although large hydrogen permeation currents were usually developed whenever large galvanic currents were established.

  12. COMPOSITE SPECTRA IN MERGING U/LIRGs CAUSED BY SHOCKS

    SciTech Connect (OSTI)

    Rich, J. A.; Kewley, L. J.; Dopita, M. A.

    2014-01-20

    We present a key result from our optical integral field spectroscopic survey of 27 nearby ultraluminous and luminous infrared galaxies (U/LIRGs) from the Great Observatory All-Sky LIRG Survey. Using spatially resolved multi-component emission line fitting to trace the emission line ratios and velocity dispersion of the ionized gas, we quantify for the first time the widespread shock ionization in gas-rich merging U/LIRGs. Our results show a fractional contribution to the total observed Hα flux from radiative shocks increasing from a few percent during early merger stages to upward of 60% of the observed optical emission line flux in late-stage mergers. We compare our resolved spectroscopy to nuclear spectra and find that 3/4 of the galaxies in our sample that would be classified as ''composite'' based on optical spectroscopy are primarily characterized by a combination of star formation and merger-driven shocks. Our results have important implications for the interpretation of ''composite'' rest-frame optical spectra of U/LIRGs as starburst+active galactic nucleus (AGN), as the shock emission combined with star formation can mimic ''composite'' optical spectra in the absence of any contribution from an AGN.

  13. Project Profile: Evaluating the Causes of Photovoltaics Cost...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Motivation Photovoltaic technologies, including silicon and thin film solar cells, have experienced unprecedented cost reductions among electricity-conversion technologies. A ...

  14. Root Cause Analysis, Contract and Project Management | Department of Energy

    Energy Savers [EERE]

    Roderick Jackson About Us Roderick Jackson - Technical Lead, Oak Ridge National Lab Roderick Jackson leads the Building Envelope Systems Research Group at the Department of Energy's Oak Ridge National Laboratory and serves as the technical lead for the Additive Manufacturing Integrated Energy (AMIE) demonstration project. He holds a bachelor's, master's, and Ph.D. in mechanical engineering from Georgia Tech. More about the AMIE demonstration project can be found:

  15. Technical Assessment Team Report on Cause of Breached Drum at...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    left, and EM Associate Deputy Assistant Secretary for Waste Management Christine Gelles also served as panelists. Panelists Update Workshop Participants on Waste Isolation...

  16. Hydrogen Embrittlement of Pipeline Steels: Causes and Remediation...

    Energy Savers [EERE]

    Presentation by 09-Sofronis to DOE Hydrogen Pipeline R&D Project Review Meeting held January 5-6, 2005 at Oak Ridge National Laboratory in Oak Ridge, Tennessee. ...

  17. Root Cause Analysis (RCA) & Corrective Action Plan (CAP) | Department...

    Energy Savers [EERE]

    Improving the Department of Energy's project and contract management continues to be one ... As part of our effort to build a strong project and contract management foundation, a root ...

  18. Hydrogen Embrittlement of Pipeline Steels: Causes and Remediation

    SciTech Connect (OSTI)

    Sofronis, Petros; Robertson, Ian M

    2013-08-01

    Fundamental studies of hydrogen embrittlement of materials using both experimental observations and numerical simulations of the hydrogen/deformation interactions have been conducted. Our approach integrates mechanical property testing at the macro-scale, microstructural analyses and TEM observations of the deformation processes at the micro- and nano-scale, first-principles calculations of interfacial cohesion at the atomic scale, and finite element simulation and modeling at the micro- and macro-level. Focused Ion Beam machining in conjunction with Transmission Electron Microscopy were used to identify the salient micro-mechanisms of failure in the presence of hydrogen. Our analysis of low strength ferritic steels led to the discovery that “quasi-cleavage” is a dislocation plasticity controlled failure mode in agreement with the hydrogen enhanced plasticity mechanism. The microstructure underneath the fracture surface of 304 and 316 stainless steels was found to be significantly more complex than would have been predicted by the traditional models of fatigue. The general refinement of the microstructure that occurred near the fracture surface in the presence of hydrogen was such that one may argue that hydrogen stabilizes microstructural configurations to an extent not achievable in its absence. Finite element studies of hydrogen and deformation field similitude for cracks in real-life pipelines and laboratory fracture specimens yielded that the Single Edge Notch Tension specimen can be used to reliably study hydrogen material compatibility for pipeline structures. In addition, simulation of onset of crack propagation in low strength ferritic systems by void growth indicated that hydrogen can reduce the fracture toughness of the material by as much as 30%. Both experimental observations and numerical studies of hydrogen transport on hydrogen accumulations ahead of a crack tip yielded that dislocation transport can markedly enhance hydrogen populations which in turn can trigger fracture initiation.

  19. Indirect Auger recombination as a cause of efficiency droop in...

    Office of Scientific and Technical Information (OSTI)

    Subject: 42 ENGINEERING solar (photovoltaic), solid state lighting, phonons, thermoelectric, bio-inspired, energy storage (including batteries and capacitors), electrodes - solar, ...

  20. Pyrin gene and mutants thereof, which cause familial Mediterranean fever

    DOE Patents [OSTI]

    Kastner, Daniel L.; Aksentijevichh, Ivona; Centola, Michael; Deng, Zuoming; Sood, Ramen; Collins, Francis S.; Blake, Trevor; Liu, P. Paul; Fischel-Ghodsian, Nathan; Gumucio, Deborah L.; Richards, Robert I.; Ricke, Darrell O.; Doggett, Norman A.; Pras, Mordechai

    2003-09-30

    The invention provides the nucleic acid sequence encoding the protein associated with familial Mediterranean fever (FMF). The cDNA sequence is designated as MEFV. The invention is also directed towards fragments of the DNA sequence, as well as the corresponding sequence for the RNA transcript and fragments thereof. Another aspect of the invention provides the amino acid sequence for a protein (pyrin) associated with FMF. The invention is directed towards both the full length amino acid sequence, fusion proteins containing the amino acid sequence and fragments thereof. The invention is also directed towards mutants of the nucleic acid and amino acid sequences associated with FMF. In particular, the invention discloses three missense mutations, clustered in within about 40 to 50 amino acids, in the highly conserved rfp (B30.2) domain at the C-terminal of the protein. These mutants include M6801, M694V, K695R, and V726A. Additionally, the invention includes methods for diagnosing a patient at risk for having FMF and kits therefor.

  1. Exceptional Ground Accelerations and Velocities Caused by Earthquakes

    SciTech Connect (OSTI)

    Anderson, John

    2008-01-17

    This project aims to understand the characteristics of the free-field strong-motion records that have yielded the 100 largest peak accelerations and the 100 largest peak velocities recorded to date. The peak is defined as the maximum magnitude of the acceleration or velocity vector during the strong shaking. This compilation includes 35 records with peak acceleration greater than gravity, and 41 records with peak velocities greater than 100 cm/s. The results represent an estimated 150,000 instrument-years of strong-motion recordings. The mean horizontal acceleration or velocity, as used for the NGA ground motion models, is typically 0.76 times the magnitude of this vector peak. Accelerations in the top 100 come from earthquakes as small as magnitude 5, while velocities in the top 100 all come from earthquakes with magnitude 6 or larger. Records are dominated by crustal earthquakes with thrust, oblique-thrust, or strike-slip mechanisms. Normal faulting mechanisms in crustal earthquakes constitute under 5% of the records in the databases searched, and an even smaller percentage of the exceptional records. All NEHRP site categories have contributed exceptional records, in proportions similar to the extent that they are represented in the larger database.

  2. Hydrogen Embrittlement of Pipeline Steels: Causes and Remediation

    Broader source: Energy.gov [DOE]

    Presentation by 09-Sofronis to DOE Hydrogen Pipeline R&D Project Review Meeting held January 5-6, 2005 at Oak Ridge National Laboratory in Oak Ridge, Tennessee.

  3. Excess Surface Area in Bioelectrochemical Systems Causes ion Transport Limitations

    SciTech Connect (OSTI)

    Harrington, Timothy D.; Babauta, Jerome T.; Davenport, Emily K.; Renslow, Ryan S.; Beyenal, Haluk

    2015-05-01

    We investigated ion transport limitations on 3D graphite felt electrodes by growing Geobacter sulfurreducens biofilms with advection to eliminate external mass transfer limitations. We characterized ion transport limitations by: (i) showing that serially increasing NaCl concentration up to 200mM increased current linearly up to a total of þ273% vs. 0mM NaCl under advective conditions; (ii) growing the biofilm with a starting concentration of 200mM NaCl, which led to a maximum current increase of 400% vs. current generation without NaCl, and (iii) showing that un-colonized surface area remained even after steadystate current was reached. After accounting for iR effects, we confirmed that the excess surface area existed despite a non-zero overpotential. The fact that the biofilm was constrained from colonizing and producing further current under these conditions confirmed the biofilms under study here were ion transport-limited. Our work demonstrates that the use of high surface area electrodes may not increase current density when the system design allows ion transport limitations to become dominant.

  4. Enhanced quantum coherence in graphene caused by Pd cluster deposition...

    Office of Scientific and Technical Information (OSTI)

    Authors: Qin, Yuyuan ; Han, Junhao ; Du, Yongping ; Li, Zhaoguo ; Wan, Xiangang ; Han, Min ; Song, Fengqi, E-mail: songfengqi@nju.edu.cn 1 ; Guo, Guoping 2 ; Song, You 3 ; Pi...

  5. Convection causes enhanced magnetic turbulence in accretion disks in outburst

    SciTech Connect (OSTI)

    Hirose, Shigenobu; Blaes, Omer; Coleman, Matthew S. B.; Krolik, Julian H.; Sano, Takayoshi

    2014-05-20

    We present the results of local, vertically stratified, radiation magnetohydrodynamic (MHD) shearing box simulations of magneto-rotational instability (MRI) turbulence appropriate for the hydrogen ionizing regime of dwarf nova and soft X-ray transient outbursts. We incorporate the frequency-integrated opacities and equation of state for this regime, but neglect non-ideal MHD effects and surface irradiation, and do not impose net vertical magnetic flux. We find two stable thermal equilibrium tracks in the effective temperature versus surface mass density plane, in qualitative agreement with the S-curve picture of the standard disk instability model. We find that the large opacity at temperatures near 10{sup 4} K, a corollary of the hydrogen ionization transition, triggers strong, intermittent thermal convection on the upper stable branch. This convection strengthens the magnetic turbulent dynamo and greatly enhances the time-averaged value of the stress to thermal pressure ratio ?, possibly by generating vertical magnetic field that may seed the axisymmetric MRI, and by increasing cooling so that the pressure does not rise in proportion to the turbulent dissipation. These enhanced stress to pressure ratios may alleviate the order of magnitude discrepancy between the ?-values observationally inferred in the outburst state and those that have been measured from previous local numerical simulations of magnetorotational turbulence that lack net vertical magnetic flux.

  6. Root Cause Analysis (RCA) & Corrective Action Plan (CAP) | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... Reserve in the Acquisition of Capital Asset projects Centralized Risk Register Tool ... Enhance project and program prioritization and associated resource allocation to minimize ...

  7. Counting small RNA in disease-causing organisms

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Counterterrorism A snapshot of NNSA's counterterrorism mission NNSA's mission of counterterrorism and counterproliferation is supported through innovative science and technology. Recently, Associate Administrator and Deputy Undersecretary for Counterterrorism and Counterproliferation Jay Tilden visited Oak Ridge National Laboratory (ORNL) and met with... Tilden appointed as Associate Administrator of Counterterrorism and Counterproliferation We are delighted to announce two key personnel

  8. Cyclone-cyclone Interactions through the Ocean Pathway

    SciTech Connect (OSTI)

    Balaguru, Karthik; Taraphdar, Sourav; Leung, Lai-Yung R.; Foltz, Gregory R.; Knaff, John A.

    2014-10-16

    The intense SST (Sea Surface Temperature) cooling caused by hurricane-induced mixing is restored at timescales on the order of weeks(1) and thus may persist long enough to influence a later hurricane passing over it. Though many studies have evaluated the effects of SST cool-ing induced by a hurricane on its own intensification(2, 3), none has looked at its effect on later storms. Using an analysis of observations and numerical model simulations, we demonstrate that hurricanes may influence the intensity of later hurricanes that pass over their linger-ing wakes. On average, when hurricanes encounter cold wakes, they experience SSTs that are ~0.4oC lower than when they do not encounter wakes and consequently decay(intensify) at a rate that is nearly three times faster(slower). In the region of warm SSTs (* 26.5oC) where the most intense and damaging hurricanes tend to occur, the percentage of hurricanes that encounter lingering cold wakes increases with hurricane frequency and was found to be as high as 40%. Furthermore, we estimate that the cumulative power dissipated(4) by the most energetic hurricanes has been reduced by as much as ~7% in a season through this effect. As the debate on changes in Atlantic hurricane activity associated with global warming(5) continues, the negative feedback between hurricane frequency and intensity resulting from hurricane-hurricane interactions through the ocean pathway deserves attention.

  9. Studying Unexplained Veteran Illnesses at the APS

    ScienceCinema (OSTI)

    Schmidt, Millicent

    2014-06-04

    Researchers from Stony Brook University come to Argonne's Advanced Photon Source to study the potential underlying causes for an unusual increased incidence of pulmonary disease in U.S. soldiers returning from military service in the Middle East and Afghanistan.

  10. Studying Unexplained Veteran Illnesses at the APS

    SciTech Connect (OSTI)

    Schmidt, Millicent

    2014-03-17

    Researchers from Stony Brook University come to Argonne's Advanced Photon Source to study the potential underlying causes for an unusual increased incidence of pulmonary disease in U.S. soldiers returning from military service in the Middle East and Afghanistan.

  11. Long range heliostat target using array of normal incidence pyranometers to evaluate a beam of solar radiation

    DOE Patents [OSTI]

    Ghanbari, Cheryl M; Ho, Clifford K; Kolb, Gregory J

    2014-03-04

    Various technologies described herein pertain to evaluating a beam reflected by a heliostat. A portable target that has an array of sensors mounted thereupon is configured to capture the beam reflected by the heliostat. The sensors in the array output measured values indicative of a characteristic of the beam reflected by the heliostat. Moreover, a computing device can generate and output data corresponding to the beam reflected by the heliostat based on the measured values indicative of the characteristic of the beam received from the sensors in the array.

  12. Role of curative radiotherapy in the treatment of lung cancer. [Clinical factors effecting efficacy and incidence of complications

    SciTech Connect (OSTI)

    Coy, P.; Kennelly, G.M.

    1980-02-15

    From 1963 to 1974, 141 patients with lung cancer were treated with curative intent in the A. Maxwell Evans Clinic in Vancouver. The clinical presentation, age and sex distribution, histology, and reasons for surgery not being carried out are examined. The results of this treatment are presented. An attempt has been made to isolate a group of patients who have a better prognosis so that treatment selection can be improved. Hemoptysis, cough, dyspnea, and incidental finding on routine chest x-ray were the most common manner of presentation. Thirty-four percent of the patients were over 70 years of age and 13% were women. The crude overall three- and five-year survival rates were 18 and 10% (19 and 9% in the men, 17 and 14% in the women). Patients presenting with dyspnea had a better survival than those presenting with cough and hemoptysis. Patients with lesions less than 3 cm in diameter had a 28% three-year survival, compared with 14% for lesions greater than 5 cm in diameter. The three- and five-year survival rates in patients over 70 years of age were 23 and 17% respectively. The response to treatment and the survival were better in the patients with squamous cell carcinoma. Twenty-two percent were alive at three years and 12% at five years as compared with 9 and 5% for other histologies. Fifty-four percent of the 35 patients with a complete response and with squamous cell carcinoma were alive at three years, compared with only 8% of the 12 patients with other histologies who showed a complete response.

  13. Estimates of the gene frequency of BRCA1 and its contribution to breast and ovarian cancer incidence

    SciTech Connect (OSTI)

    Ford, D.; Easton, D.F.; Peto, J.

    1995-12-01

    The majority of multiple-case families that segregate both breast and ovarian cancer in a dominant fashion are due to mutations in the BRCA1 gene on chromosome 17q. In this paper, we have combined penetrance estimates for BRCA1 with the results of two population-based genetic epidemiological studies to estimate the gene frequency of BRCA1. On the assumption that the excess risk of ovarian cancer in first degree relatives of breast cancer patients and the breast cancer excess in relatives of ovarian cancer patients are both entirely accounted for by BRCA1, we estimate that the BRCA1 gene frequency is 0.0006 (95% confidence interval [0.0002-0.001]) and that the proportion of breast cancer cases in the general population due to BRCA1 is 5.3% below age 40 years, 2.2% between ages 40 and 49 years, and 1.1% between ages 50 and 70 years. The corresponding estimates for ovarian cancer are 5.7%, 4.6%, and 2.1%, respectively. Our results suggest that the majority of breast cancer families with less than four cases and no ovarian cancer are not due to rare highly penetrant genes such as BRCA1 but are more likely to be due either to chance or to more common genes of lower penetrance. 22 refs., 3 tabs.

  14. New Mexico Governor Susana Martinez and U.S Energy Secretary Ernest Moniz Announce Settlement on Nuclear Waste Incidents

    Broader source: Energy.gov [DOE]

    Press Release on the Department of Energy and the State of New Mexico's agreement to projects for safer roads, improved water infrastructure and enhanced emergency response.

  15. Reciprocal space XRD mapping with varied incident angle as a probe of structure variation within surface depth

    SciTech Connect (OSTI)

    Yang, Qiguang; Williams, Frances; Zhao, Xin; Reece, Charles E.; Krishnan, Mahadevan

    2013-09-01

    In this study, we used a differential-depth X-Ray diffraction Reciprocal Spacing Mapping (XRD RSM) technique to investigate the crystal quality of a variety of SRF-relevant Nb film and bulk materials. By choosing different X-ray probing depths, the RSM study successfully revealed evolution the of materials? microstructure after different materials processes, such as energetic condensation or surface polishing. The RSM data clearly measured the materials? crystal quality at different thickness. Through a novel differential-depth RSM technique, this study found: I. for a heteroepitaxy Nb film Nb(100)/MgO(100), the film thickening process, via a cathodic arc-discharge Nb ion deposition, created a near-perfect single crystal Nb on the surface?s top-layer; II. for a mechanically polished single-crystal bulk Nb material, the microstructure on the top surface layer is more disordered than that in-grain.

  16. How Clean is Safe? Improving the Effectiveness of Decontamination of Structures and People Following Chemical and Biological Incidents

    SciTech Connect (OSTI)

    Vogt , B.M.

    2003-04-03

    This report describes a U.S. Department of Energy, (DOE) Chemical and Biological National Security Program project that sought to establish what is known about decontamination of structures, objects, and people following an exposure to chemical or biological materials. Specifically we sought to identify the procedures and protocols used to determine when and how people or buildings are considered ''clean'' following decontamination. To fulfill this objective, the study systematically examined reported decontamination experiences to determine what procedures and protocols are currently employed for decontamination, the timeframe involved to initiate and complete the decontamination process, how the contaminants were identified, the factors determining when people were (or were not) decontaminated, the problems encountered during the decontamination process, how response efforts of agencies were coordinated, and the perceived social psychological effects on people who were decontaminated or who participated in the decontamination process. Findings and recommendations from the study are intended to aid decision-making and to improve the basis for determining appropriate decontamination protocols for recovery planners and policy makers for responding to chemical and biological events.

  17. Revised: December, 2008

    U.S. Energy Information Administration (EIA) Indexed Site

    E4. Electricity Consumption (Btu) Intensities by End Use for Non-Mall Buildings, 2003" ,"Electricity Energy Intensity (thousand Btusquare foot)" ,"Total ","Space Heat- ing","Cool-...

  18. Released: September, 2008

    U.S. Energy Information Administration (EIA) Indexed Site

    E4A. Electricity Consumption (Btu) Intensities by End Use for All Buildings, 2003" ,"Electricity Energy Intensity (thousand Btusquare foot)" ,"Total ","Space Heat- ing","Cool-...

  19. 1992 CBECS BC

    U.S. Energy Information Administration (EIA) Indexed Site

    A57. Energy Conservation Features, Number of Buildings and Floorspace, 1992 Building Characteristics RSE Column Factor: Number of Buildings (thousand) Total Floorspace (million square feet) RSE Row Factor All Buildings Any Conser- vation Features Build- ing Shell HVAC Light- ing Other All Buildings Any Conser- vation Features Build- ing Shell HVAC Light- ing Other 0.8 0.8 0.8 0.9 1.0 1.9 0.8 0.9 0.9 0.9 1.2 1.7 All Buildings ................................... 4,806 4,357 4,223 2,604 1,178 264

  20. BWX TYmes, October 2003

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Administration conference in Washington, D.C., ... Diskless technology has several benefits in ... and factory floor systems. Network- ing, remote computers and remote ...

  1. B

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The slanted rotor allows the turbine to self-start without any external devices. This passive-control system offers power generation without the noise, clutch- ing,...

  2. The

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... engineering of hydrogen technologies, Sandia is advancing hydrogen as an energy carrier, improv- ing fuel cells and hydrogen storage, as well as safety, codes and standards. ...

  3. SANDIA REPORT SAND93-1076

    Office of Scientific and Technical Information (OSTI)

    ... procedures were not per- ing bit-rate demands, formed in a standard repeated method ... Proper operational proce- The standard IDR optical termination panel dures, ...

  4. PSADEFS.CHP:Corel VENTURA

    Gasoline and Diesel Fuel Update (EIA)

    ASTM. The acronym for the American Society for Test- ing and Materials. Atmospheric Crude ... Example: (1) Unextracted paraffinic oils that would not meet the Viscosity Index test. ...

  5. Evince Technology | Open Energy Information

    Open Energy Info (EERE)

    Evince Technology Jump to: navigation, search Name: Evince Technology Place: United Kingdom Sector: Efficiency, Wind energy Product: String representation "Evince has pion ... ing...

  6. Microsoft Word - doe_preamble_04.doc

    Office of Scientific and Technical Information (OSTI)

    ... Demmel, W. J. "Applied Numerical Linear Algebra". Society for Industrial and Applied ... Their work demonstrates that the use of standard upscal- ing procedures can be ...

  7. Sensor Technologies for a Smart Transmission System An EPRI White...

    Broader source: Energy.gov (indexed) [DOE]

    ... Re- searchers are also looking into the possibility of conduct- ing future inspections by unmanned airborne vehicles (UAVs). The advantage of this approach is that the data ...

  8. --No Title--

    Gasoline and Diesel Fuel Update (EIA)

    2. Water Heating Equipment, Number of Buildings and Floorspace for Non-Mall Buildings, 2003 Number of Buildings (thousand) Total Floorspace (million square feet) All Build- ings*...

  9. ch_1

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... The Nuclear Waste Policy Act of 1982, as amended, determined that a geological repository ... obtain- ing representative con- stituent samples from the large volumes of mixed ...

  10. Hydropower Vision Chapter 4: The Hydropower Vision: A Pathway...

    Broader source: Energy.gov (indexed) [DOE]

    ... new professionals to enter the hydropower field. 4 350 ... compliance, financing terms, and revenue sources-may ... and varied, which makes search- ing and assimilating data ...

  11. ch_5

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    44 Environmental Consequences 5.2.7 WATER RESOURCES This section presents potential water resource impacts from implement- ing the proposed waste processing alternatives described ...

  12. Ultrahigh-Efficiency Aluminum Production Cells

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Aluminum is an indispensable metal in modern manufactur- ing. Its lightweight, low density, corrosion resistance, and easy processing possibilities, coupled with its suitability ...

  13. ch_5

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... by the application of water, use of soil additives, and ... and health impacts from atmospheric emissions from the waste ... compactors) and portable generators dur- ing construction ...

  14. 04100001inside-layout.indd

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... ing nearly eliminated atmospheric releases of radiation ... to contami- nated soil or water on the NTS, have moved off ... the emissions were nitrogen oxides from diesel generators. ...

  15. Untitled Document

    Office of Scientific and Technical Information (OSTI)

    To achieve these goals, we have implemented an application that uses shared rendering. Shared rendering refers to a cooperative visualization and render- ing framework in which ...

  16. Long-Term Surveillance Plan for the Upper Burbank Disposal Cell...

    Office of Legacy Management (LM)

    ... Demonstration that IicensrIng provisions were met. Information needed to forecast future ... Energy, Environmental Restoration D'iision, UMTRA Project Team, Albuquerque, New Mexico. ...

  17. --No Title--

    U.S. Energy Information Administration (EIA) Indexed Site

    3. Cooking Energy Sources, Number of Buildings and Floorspace for Non-Mall Buildings, 2003 Number of Buildings (thousand) Total Floorspace (million square feet) All Build- ings*...

  18. ,"Total District Heat Consumption (trillion Btu)",,,,,"District...

    U.S. Energy Information Administration (EIA) Indexed Site

    Heat Consumption (trillion Btu)",,,,,"District Heat Energy Intensity (thousand Btusquare foot)" ,"Total ","Space Heating","Water Heating","Cook- ing","Other","Total ","Space...

  19. ,"Total Natural Gas Consumption (trillion Btu)",,,,,"Natural...

    U.S. Energy Information Administration (EIA) Indexed Site

    Gas Consumption (trillion Btu)",,,,,"Natural Gas Energy Intensity (thousand Btusquare foot)" ,"Total ","Space Heating","Water Heating","Cook- ing","Other","Total ","Space...

  20. ,"Total Natural Gas Consumption

    U.S. Energy Information Administration (EIA) Indexed Site

    Gas Consumption (billion cubic feet)",,,,,"Natural Gas Energy Intensity (cubic feetsquare foot)" ,"Total ","Space Heating","Water Heating","Cook- ing","Other","Total ","Space...