Sample records for improvement network brain

  1. Functional Clustering Drives Encoding Improvement in a Developing Brain Network during Awake Visual Learning

    E-Print Network [OSTI]

    Dunfield, Derek

    Sensory experience drives dramatic structural and functional plasticity in developing neurons. However, for single-neuron plasticity to optimally improve whole-network encoding of sensory information, changes must be ...

  2. STOCHASTIC GENERATION OF BIOLOGICALLY ACCURATE BRAIN NETWORKS

    E-Print Network [OSTI]

    STOCHASTIC GENERATION OF BIOLOGICALLY ACCURATE BRAIN NETWORKS A Thesis by ARAVIND ALURI Submitted OF BIOLOGICALLY ACCURATE BRAIN NETWORKS A Thesis by ARAVIND ALURI Submitted to the Office of Graduate Studies Head of Department, Valerie Taylor December 2005 Major Subject: Computer Science #12;iii ABSTRACT

  3. Network induces burst synchronisation in cat brain

    E-Print Network [OSTI]

    Ewandson L. Lameu; Fernando S. Borges; Rafael R. Borges; Antonio M. Batista; Murilo S. Baptista; Ricardo L. Viana

    2015-03-07T23:59:59.000Z

    The brain of mammals are divided into different cortical areas that are anatomically connected forming larger networks which perform cognitive tasks. The cat cerebral cortex is composed of 65 areas organised into the visual, auditory, somatosensory-motor and frontolimbic cognitive regions. We have built a network of networks, in which networks are connected among themselves according to the connections observed in the cat cortical areas aiming to study how inputs drive the synchronous behaviour in this cat brain-like network. We show that without external perturbations it is possible to observe high level of bursting synchronisation between neurons within almost all areas, except for the auditory area. Bursting synchronisation appears between neurons in the auditory region when an external perturbation is applied in another cognitive area. This is a clear evidence that pattern formation and collective behaviour in the brain might be a process mediated by other brain areas under stimulation.

  4. Neuronal and network computation in the brain

    SciTech Connect (OSTI)

    Babloyantz, A. [Center for Study of Non-linear Systems, Universite Libre de Bruxelles, CP 231, Boulevard du Triomphe, 1050 Brussels (Belgium); International Solvay Institutes for Physics and Chemistry, ULB-Campus Plaine-CP 231, Boulevard du Triomphe, 1050 Brussels (Belgium)

    1999-03-22T23:59:59.000Z

    The concepts and methods of non-linear dynamics have been a powerful tool for studying some gamow aspects of brain dynamics. In this paper we show how, from time series analysis of electroencepholograms in sick and healthy subjects, chaotic nature of brain activity could be unveiled. This finding gave rise to the concept of spatiotemporal cortical chaotic networks which in turn was the foundation for a simple brain-like device which is able to become attentive, perform pattern recognition and motion detection. A new method of time series analysis is also proposed which demonstrates for the first time the existence of neuronal code in interspike intervals of coclear cells.

  5. Scale-Free Brain Functional Networks Victor M. Eguiluz,1

    E-Print Network [OSTI]

    Oro, Daniel

    Scale-Free Brain Functional Networks Victor M. Egui´luz,1 Dante R. Chialvo,2 Guillermo A. Cecchi,3 is used to extract functional networks connecting correlated human brain sites. Analysis of the resulting-world networks, reflect important functional information about brain states. DOI: 10.1103/PhysRevLett.94

  6. When Network Coding improves the Performances of Clustered Wireless Networks

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    When Network Coding improves the Performances of Clustered Wireless Networks that significantly increases the performances of clustering algorithms in wireless multi-hop networks-XOR coding; wireless multi-hop networks; clustering I. INTRODUCTION Partitioning nodes

  7. Computational Neuropsychiatry - Schizophrenia as a Cognitive Brain Network Disorder

    E-Print Network [OSTI]

    Dauvermann, Maria R.

    Computational modeling of functional brain networks in fMRI data has advanced the understanding of higher cognitive function. It is hypothesized that functional networks mediating higher cognitive processes are disrupted ...

  8. Abstract--Recent brain imaging studies on primates revealed that a network of brain areas is activated both during

    E-Print Network [OSTI]

    Trahanias, Panos

    9 Abstract-- Recent brain imaging studies on primates revealed that a network of brain areas and constitutes an efficient behavior of mammals. Recent brain imaging studies investigate where and how observed to this direction [23]. Additional studies [10],[16] indicate the existence of a much wider network of brain areas

  9. Complex Networks - A Key to Understanding Brain Function

    SciTech Connect (OSTI)

    Olaf Sporns

    2008-01-23T23:59:59.000Z

    The brain is a complex network of neurons, engaging in spontaneous and evoked activity that is thought to be the main substrate of mental life.  How this complex system works together to process information and generate coherent cognitive states, even consciousness, is not yet well understood.  In my talk I will review recent studies that have revealed characteristic structural and functional attributes of brain networks, and discuss efforts to build computational models of the brain that are informed by our growing knowledge of brain anatomy and physiology.

  10. Complex Networks - A Key to Understanding Brain Function

    ScienceCinema (OSTI)

    Olaf Sporns

    2010-01-08T23:59:59.000Z

    The brain is a complex network of neurons, engaging in spontaneous and evoked activity that is thought to be the main substrate of mental life.  How this complex system works together to process information and generate coherent cognitive states, even consciousness, is not yet well understood.  In my talk I will review recent studies that have revealed characteristic structural and functional attributes of brain networks, and discuss efforts to build computational models of the brain that are informed by our growing knowledge of brain anatomy and physiology.

  11. An Algebraic Topological Method for Multimodal Brain Networks Comparisons

    E-Print Network [OSTI]

    Simas, Tiago; Rodriguez, Pablo; Diaz-Guilera, Albert

    2015-01-01T23:59:59.000Z

    Understanding brain connectivity has become one of the most important issues in neuroscience. But connectivity data can reflect either the functional relationships of the brain activities or the anatomical properties between brain areas. Although one should expect a clear relationship between both representations it is not straightforward. Here we present a formalism that allows for the comparison of structural (DTI) and functional (fMRI) networks by embedding both in a common metric space. In this metric space one can then find for which regions the two networks are significantly different. Our methodology can be used not only to compare multimodal networks but also to extract statistically significant aggregated networks of a set of subjects. Actually, we use this procedure to aggregate a set of functional (fMRI) networks from different subjects in an aggregated network that is compared with the anatomical (DTI) connectivity. The comparison of the aggregated network reveals some features that are not observ...

  12. INTERACTING WITH SOCIAL NETWORKS TO IMPROVE HEALTHCARE BODY SENSOR NETWORKS

    E-Print Network [OSTI]

    Miles, Will

    INTERACTING WITH SOCIAL NETWORKS TO IMPROVE HEALTHCARE BODY SENSOR NETWORKS by DAVID BAUSCHLICHER monitor and record data while minimizing the energy expenditure of nodes in the BSN. Social networking to a social network creates the unique ability to share health related data with other users through social

  13. ScaleScale--free Brain Functional Networksfree Brain Functional Networks victor@imedea.uib.es www.imedea.uib.es/~victor

    E-Print Network [OSTI]

    Oro, Daniel

    ScaleScale--free Brain Functional Networksfree Brain Functional Networks victor@imedea.uib.es wwwPlan Motivation: Networks & Brain How to get functional networks from fMRI Characterization of brain functional) Co-authorship of scientific papers #12;...... and the brainand the brain #12;""In catalogue" cortical

  14. abnormal brain mri: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    abnormal brain mri First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Improvement of MRI brain...

  15. Hubs of brain functional networks are radically reorganized in comatose patients

    E-Print Network [OSTI]

    Boyer, Edmond

    Hubs of brain functional networks are radically reorganized in comatose patients S. Achard , C Human brain networks have topological properties in common with many other complex systems, prompting the question: what aspects of brain network organization are critical for distinctive functional properties

  16. Stochastic generation of biologically accurate brain networks

    E-Print Network [OSTI]

    Aluri, Aravind

    2006-04-12T23:59:59.000Z

    . . . . . . . . . . . . . . . . . . 5 1. Canonical or basic circuits . . . . . . . . . . . . . . . . 5 2. Visualization . . . . . . . . . . . . . . . . . . . . . . . 7 3. Stochastic generation and network formation . . . . . 8 4. Network processing and analysis... . . . . . . . . . . . . . . . . 55 3. De?nition of CircuitParams class . . . . . . . . . . . . 57 4. De?nition of Circuit.neu con?guration ?le . . . . . . . 59 5. De?nition of CircuitParser class . . . . . . . . . . . . 61 6. Modi?cation to OpenDX visualization output . . . . . 61 7...

  17. Dynamic reconfiguration of human brain networks during learning

    E-Print Network [OSTI]

    Danielle S. Bassett; Nicholas F. Wymbs; Mason A. Porter; Peter J. Mucha; Jean M. Carlson; Scott T. Grafton

    2011-10-24T23:59:59.000Z

    Human learning is a complex phenomenon requiring flexibility to adapt existing brain function and precision in selecting new neurophysiological activities to drive desired behavior. These two attributes -- flexibility and selection -- must operate over multiple temporal scales as performance of a skill changes from being slow and challenging to being fast and automatic. Such selective adaptability is naturally provided by modular structure, which plays a critical role in evolution, development, and optimal network function. Using functional connectivity measurements of brain activity acquired from initial training through mastery of a simple motor skill, we explore the role of modularity in human learning by identifying dynamic changes of modular organization spanning multiple temporal scales. Our results indicate that flexibility, which we measure by the allegiance of nodes to modules, in one experimental session predicts the relative amount of learning in a future session. We also develop a general statistical framework for the identification of modular architectures in evolving systems, which is broadly applicable to disciplines where network adaptability is crucial to the understanding of system performance.

  18. Performance Improvements for Nuclear Reaction Network Integration

    E-Print Network [OSTI]

    Longland, Richard; José, Jordi

    2014-01-01T23:59:59.000Z

    Aims: The aim of this work is to compare the performance of three reaction network integration methods used in stellar nucleosynthesis calculations. These are the Gear's backward differentiation method, Wagoner's method (a 2nd-order Runge-Kutta method), and the Bader-Deuflehard semi-implicit multi-step method. Methods: To investigate the efficiency of each of the integration methods considered here, a test suite of temperature and density versus time profiles is used. This suite provides a range of situations ranging from constant temperature and density to the dramatically varying conditions present in white dwarf mergers, novae, and x-ray bursts. Some of these profiles are obtained separately from full hydrodynamic calculations. The integration efficiencies are investigated with respect to input parameters that constrain the desired accuracy and precision. Results: Gear's backward differentiation method is found to improve accuracy, performance, and stability in integrating nuclear reaction networks. For te...

  19. Improving performance of TCP over wireless networks

    E-Print Network [OSTI]

    Mehta, Miten N.

    1998-01-01T23:59:59.000Z

    TCP has been designed and tuned to perform well on a phics. wired network made up of links with low bit-error rates. Wireless networks and heterogeneous networks consisting of wired and wireless links have many different characteristics compared...

  20. An improved dosimetric model of the head and brain

    E-Print Network [OSTI]

    Bouchet, Lionel Gerard

    1995-01-01T23:59:59.000Z

    Br). Other radionuclides considered may deposit in bone withm the head region (cranium or the spinal skeleton) (is'I, 2P, ssP, tssRe, 'ssRe, 'ssSm, "7~Sb, ssSr, s Sr, "nY, ss~Tc, tsiCs, ss"Ra), or m the thyroid fss~ Tc, and all iodme radionuclides... tagged to them (i. e. , radiopharmaceuticals). Nevertheless, studies of the small-scale dosimetry of the bram, and more generally, the organs of the head (brain, eyes thyroid, skull, skin), have not kept pace with the current advances in nuclear...

  1. Semi-Automated Reconstruction of Vascular Networks in Knife-Edge Scanning Microscope Mouse Brain Data

    E-Print Network [OSTI]

    Dileepkumar, Ananth

    2014-08-14T23:59:59.000Z

    The KnifeEdge Scanning Microscope (KESM) enables imaging of an entire mouse brain at sub-micrometer resolution. The data from KESM can be used in the reconstruction of neuronal and vascular structures in the mouse brain. Tracing the vascular network...

  2. Scalable Brain Network Construction on White Matter Fibers Moo K. Chung1,3,6

    E-Print Network [OSTI]

    Chung, Moo K.

    of white matter fibers are connected so we are actually dealing with paired point cloud data. SoScalable Brain Network Construction on White Matter Fibers Moo K. Chung1,3,6 , Nagesh Adluru3 to characterize the structural connectivity of the human brain non-invasively by tracing white matter fiber tracts

  3. Classification of brain compartments and head injury lesions by neural networks applied to magnetic resonance images

    E-Print Network [OSTI]

    Kischell, Eric Robert

    1993-01-01T23:59:59.000Z

    ' (Member) A. D. Patton ( ead of epartment) August 1993 Major Subject: Electrical Engineering ABSTRACT Classification of Brain Compartments and Head Injury Lesions by Neural Networks Applied to Magnetic Resonance Images. (August 1993) Eric Robert... Kischell, B. S. , Northeastern University Chair of Advisory Committee: Dr. Nasser Kehtarnavaz An automatic neural network-based approach was ap- plied to segment brain compartments and closed-head-injury lesions in magnetic resonance (MR) images Two...

  4. adult rodent brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    adult rodent brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 RODENT BRAIN NAVIGATOR :RODENT BRAIN...

  5. Improved techniques for passive optical networks

    E-Print Network [OSTI]

    Jorgesen, Douglas Ryan Tourtillott

    2010-01-01T23:59:59.000Z

    for WDM Access Networks with Downstream DPSK and UpstreamReturn to Zero (RZ) Coded Downstream and NRZ Upstream Re-Access Network Scheme with Downstream Manchester Coding and

  6. Improving Network Reliability: Analysis, Methodology, and Algorithms

    E-Print Network [OSTI]

    Booker, Graham B.

    2010-07-14T23:59:59.000Z

    The reliability of networking and communication systems is vital for the nation's economy and security. Optical and cellular networks have become a critical infrastructure and are indispensable in emergency situations. This dissertation outlines...

  7. Abstract-Understanding the clinical outcomes of brain lesions necessitates knowing how networks of cerebral structures

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Abstract- Understanding the clinical outcomes of brain lesions necessitates knowing how networks-scale cerebral networks I. INTRODUCTION The understanding and the prediction of the clinical outcomes of cerebral explicit enough to be directly used for clinical purpose. In fact, few researches answer the question

  8. Improved Imaged-derived Input Function for Study of Human Brain FDG-PET

    E-Print Network [OSTI]

    Renaut, Rosemary

    Improved Imaged-derived Input Function for Study of Human Brain FDG-PET Hongbin Guo, Rosemary tomography (PET) studies. Two time windows can be recognized in the time activity curve measured from the compartmental model for FDG PET [5]. Index Terms Quantification of FDG PET, Automated Image-derived input

  9. IMPROVED QUANTITATIVE METHODS FOR MULTIPLE NEUROPHARMACOLOGICAL NON-INVASIVE BRAIN PET STUDIES

    E-Print Network [OSTI]

    Fessler, Jeffrey A.

    i IMPROVED QUANTITATIVE METHODS FOR MULTIPLE NEUROPHARMACOLOGICAL NON-INVASIVE BRAIN PET STUDIES.2.2 Multiple Neuropharmacological Measures from a single PET scan ................. 4 1.2.2.1 Dual ...................................................................................... 5 1.2.3 Reduction of inter-scanner PET image variability

  10. abnormal brain glucose: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    (PNH) is a malformation of cortical development associated with epilepsy and dyslexia. Evidence suggests that heterotopic gray matter can be functional in brain...

  11. abnormal brain morphology: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    (PNH) is a malformation of cortical development associated with epilepsy and dyslexia. Evidence suggests that heterotopic gray matter can be functional in brain...

  12. abnormal brain processing: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    (PNH) is a malformation of cortical development associated with epilepsy and dyslexia. Evidence suggests that heterotopic gray matter can be functional in brain...

  13. abnormal brain iron: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    (PNH) is a malformation of cortical development associated with epilepsy and dyslexia. Evidence suggests that heterotopic gray matter can be functional in brain...

  14. abnormal brain ct: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    (PNH) is a malformation of cortical development associated with epilepsy and dyslexia. Evidence suggests that heterotopic gray matter can be functional in brain...

  15. abnormal brain connection: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    (PNH) is a malformation of cortical development associated with epilepsy and dyslexia. Evidence suggests that heterotopic gray matter can be functional in brain...

  16. aggressive brain tumor: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    aggressive brain tumor First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Brain oxytocin correlates with...

  17. auditory brain stem implantation: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    auditory brain stem implantation First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Auditory Brain Stem...

  18. alzheimer disease brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    alzheimer disease brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Brain MRI segmentation for the...

  19. adult brain tumor: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    brain tumor First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Transcriptional signature of an adult brain...

  20. aging brain relevance: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    aging brain relevance First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Brain Evolution Relevant to P....

  1. alzheimers disease brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    alzheimers disease brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Brain MRI segmentation for the...

  2. american brain tumor: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    american brain tumor First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Efficient Multilevel Brain Tumor...

  3. auditory brain stem implants: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    brain stem implants First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Auditory Brain Stem Response to...

  4. auditory brain stem: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    brain stem First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Auditory Brain Stem Response to Complex...

  5. animal brain tissues: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    animal brain tissues First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Temperature Effects on Brain...

  6. avian brain tissue: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    brain tissue First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Song recognition in the avian brain...

  7. acute brain slices: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    acute brain slices First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Brain Slice Chamber System Biology...

  8. auditory brain regions: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    auditory brain regions First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 930 Brain imaging Sex...

  9. amusic brain lost: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    amusic brain lost First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 doi:10.1093brainawl204 Brain...

  10. adult mice brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    mice brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Survey of Brain Variations of Young Adult...

  11. acetazolamide stress brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    acetazolamide stress brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Changes in Brain MicroRNAs...

  12. affects brain activity: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    affects brain activity First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Brain Research, 347(1985)85-93...

  13. Improved Classification of Medical Data Using Abductive Network Committees

    E-Print Network [OSTI]

    Abdel-Aal, Radwan E.

    Improved Classification of Medical Data Using Abductive Network Committees Trained on Different 3 860 4281 #12;Summary This paper demonstrates the use of abductive network classifier committees the features and forming subsets of uniform predictive quality for training individual members. The abductive

  14. Proteins, anatomy and networks of the fruit fly brain 

    E-Print Network [OSTI]

    Knowles-Barley, Seymour Francis

    2012-06-25T23:59:59.000Z

    Our understanding of the complexity of the brain is limited by the data we can collect and analyze. Because of experimental limitations and a desire for greater detail, most investigations focus on just one aspect of the ...

  15. Neuron-glia networks: integral gear of brain function

    E-Print Network [OSTI]

    Perea, Gertrudis

    Astrocytes, the most abundant glial cell in the brain, play critical roles in metabolic and homeostatic functions of the Nervous System; however, their participation in coding information and cognitive processes has been ...

  16. alzheimer disease brains: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Brain MRI segmentation for the longitudinal follow-up of regional atrophy in Alzheimers...

  17. activate brain sulfonylurea-sensitive: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    activate brain sulfonylurea-sensitive First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Complex networks...

  18. Improved Cognitive Function After Transcranial, Light-Emitting Diode Treatments in Chronic, Traumatic Brain Injury: Two Case Reports

    E-Print Network [OSTI]

    Naeser, Margaret A.

    Objective: Two chronic, traumatic brain injury (TBI) cases, where cognition improved following treatment with red and near-infrared light-emitting diodes (LEDs), applied transcranially to forehead and scalp areas, are ...

  19. approach demonstrates brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    approach demonstrates brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Subliminal Instrumental...

  20. adult astrocytic brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    adult astrocytic brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 New Neurons Clear the Path of...

  1. adult drosophila brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    adult drosophila brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Cell proliferation in the...

  2. acute brain injury: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    acute brain injury First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Acute Injury Phase Clinical Trials...

  3. activated brain microglia: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    activated brain microglia First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Endotoxin-activated microglia...

  4. adult zebrafish brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    adult zebrafish brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Molecular control of neurogenesis...

  5. adult vertebrate brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    adult vertebrate brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Introduction The vertebrate...

  6. abca1 increases brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    abca1 increases brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Unsaturated fatty acids...

  7. adolescent brain development: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    adolescent brain development First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 NEW UNDERSTANDING OF...

  8. aging mouse brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    aging mouse brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Construction of Anatomically Correct...

  9. artery simulating brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    artery simulating brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Multiscale simulation of blood...

  10. adult brain tumors: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    adult brain tumors First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Transcriptional signature of an...

  11. adult rat brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    rat brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Thyroid hormone regulates hippocampal...

  12. aged human brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    aged human brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Chemical Heterogeneity of the Living...

  13. acquired brain injuries: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    acquired brain injuries First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Students requesting...

  14. acute brain stem: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    brain stem First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Acute Injury Phase Clinical Trials in Acute...

  15. ageing human brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ageing human brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Chemical Heterogeneity of the Living...

  16. assessing blood brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    blood brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Noninvasive in vivo optical assessment of...

  17. adult porcine brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    adult porcine brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Zo Rebecca Hunter Plasticity of the...

  18. acute brain ischemia: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    brain ischemia First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Acute functional recovery of cerebral...

  19. acquired brain injury: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    acquired brain injury First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Students requesting...

  20. asphyxia induced brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    asphyxia induced brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Perinatal Asphyxia Induces...

  1. attenuate postischemic brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    attenuate postischemic brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Eukaryotic Initiation...

  2. aggregating brain cell: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    aggregating brain cell First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Biomimetic Dye Aggregate Solar...

  3. altered gravity brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    altered gravity brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Understanding Alterations in...

  4. adult mouse brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    adult mouse brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Mapping of Endogenous Morphine-Like...

  5. adolescent brain insights: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    adolescent brain insights First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 NEW UNDERSTANDING OF...

  6. acute brain trauma: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    acute brain trauma First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Acute Injury Phase Clinical Trials...

  7. astrocytic brain tumors: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    astrocytic brain tumors First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 astrocytic tumors: a role for...

  8. aerosolized brain natriuretic: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    aerosolized brain natriuretic First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Natriuretic Peptides,...

  9. automated brain labeling: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    automated brain labeling First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Automated Talairach Atlas...

  10. adult human brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    adult human brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Zo Rebecca Hunter Plasticity of the...

  11. acute ischemic brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ischemic brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Statistical prediction of tissue fate in...

  12. acute traumatic brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    traumatic brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Acute Injury Phase Clinical Trials in...

  13. automatic brain tumor: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    automatic brain tumor First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 UNSUPERVISED SEGMENTATION FOR...

  14. acquired brain damage: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    acquired brain damage First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Virtual Reality Rehabilitation of...

  15. awake brain states: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    awake brain states First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Optimised Motion Tracking for...

  16. Experimental Evaluation of Performance Improvements in Abductive Network Classifiers with Problem Decomposition

    E-Print Network [OSTI]

    Abdel-Aal, Radwan E.

    1 Experimental Evaluation of Performance Improvements in Abductive Network Classifiers with Problem by problem decomposition for abductive network classifiers that classify four noisy waveform patterns having decomposition method and significantly superior to an abductive network committee approach. Index Terms

  17. Converging Redundant Sensor Network Information for Improved Building Control

    SciTech Connect (OSTI)

    Dale K. Tiller; Gregor P. Henze

    2005-12-01T23:59:59.000Z

    This project is investigating the development and application of sensor networks to enhance building energy management and security. Commercial, industrial and residential buildings often incorporate systems used to determine occupancy, but current sensor technology and control algorithms limit the effectiveness of these systems. For example, most of these systems rely on single monitoring points to detect occupancy, when more than one monitoring point would improve system performance. Phase I of the project focused on instrumentation and data collection. In Phase I, a new occupancy detection system was developed, commissioned and installed in a sample of private offices and open-plan office workstations. Data acquisition systems were developed and deployed to collect data on space occupancy profiles. In phase II of the project, described in this report, we demonstrate that a network of several sensors provides a more accurate measure of occupancy than is possible using systems based on single monitoring points. We also establish that analysis algorithms can be applied to the sensor network data stream to improve the accuracy of system performance in energy management and security applications, and show that it may be possible to use sensor network pulse rate to distinguish the number of occupants in a space. Finally, in this phase of the project we also developed a prototype web-based display that portrays the current status of each detector in a sensor network monitoring building occupancy. This basic capability will be extended in the future by applying an algorithm-based inference to the sensor network data stream, so that the web page displays the likelihood that each monitored office or area is occupied, as a supplement to the actual status of each sensor.

  18. Converging Redundant Sensor Network Information for Improved Building Control

    SciTech Connect (OSTI)

    Dale Tiller; D. Phil; Gregor Henze; Xin Guo

    2007-09-30T23:59:59.000Z

    This project investigated the development and application of sensor networks to enhance building energy management and security. Commercial, industrial and residential buildings often incorporate systems used to determine occupancy, but current sensor technology and control algorithms limit the effectiveness of these systems. For example, most of these systems rely on single monitoring points to detect occupancy, when more than one monitoring point could improve system performance. Phase I of the project focused on instrumentation and data collection. During the initial project phase, a new occupancy detection system was developed, commissioned and installed in a sample of private offices and open-plan office workstations. Data acquisition systems were developed and deployed to collect data on space occupancy profiles. Phase II of the project demonstrated that a network of several sensors provides a more accurate measure of occupancy than is possible using systems based on single monitoring points. This phase also established that analysis algorithms could be applied to the sensor network data stream to improve the accuracy of system performance in energy management and security applications. In Phase III of the project, the sensor network from Phase I was complemented by a control strategy developed based on the results from the first two project phases: this controller was implemented in a small sample of work areas, and applied to lighting control. Two additional technologies were developed in the course of completing the project. A prototype web-based display that portrays the current status of each detector in a sensor network monitoring building occupancy was designed and implemented. A new capability that enables occupancy sensors in a sensor network to dynamically set the 'time delay' interval based on ongoing occupant behavior in the space was also designed and implemented.

  19. PET Imaging of Brain 5-HT1A Receptors in Rat In Vivo with 18F-FCWAY and Improvement by

    E-Print Network [OSTI]

    Shen, Jun

    PET Imaging of Brain 5-HT1A Receptors in Rat In Vivo with 18F-FCWAY and Improvement by Successful)cyclohexanecarboxamide) is useful in clinical research with PET for measuring serotonin 1A (5-HT1A) re- ceptor densities in brain applicability to measuring brain regional 5-HT1A receptor densities. Methods: PET of rat head after

  20. Picturing the brain from different perspectives: the neuroimaging of early AD The last 150 years have witnessed dramatic improvements in the field of what we

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    EDITORIAL Picturing the brain from different perspectives: the neuroimaging of early AD The last. The description of the clinical and cognitive signs of specific brain diseases, as well as our understanding of normal brain function have been considerably improved, thanks to research ranging from anatomoclinical

  1. Improving the performance of distributed simulations of wireless sensor networks

    E-Print Network [OSTI]

    Jin, Zhong-Yi

    2010-01-01T23:59:59.000Z

    Overview of Wireless Sensor Networks . . 2.1.2 Difficultiesin parallel a wireless sensor network with two duty cycledin parallel a wireless sensor network with three nodes that

  2. Wireless Sensor Network for Improving the Energy Efficiency of Data Centers

    E-Print Network [OSTI]

    LBNL-6253E Wireless Sensor Network for Improving the Energy Efficiency of Data Centers Rod Mahdavi for Improving the Energy Efficiency of Data Centers Page i Disclaimer This document@lbl.gov www.lbl.gov #12;Wireless Sensor Network for Improving the Energy Efficiency

  3. Optogenetic Brain Interfaces

    E-Print Network [OSTI]

    Pashaie, Ramin

    The brain is a large network of interconnected neurons where each cell functions as a nonlinear processing element. Unraveling the mysteries of information processing in the complex networks of the brain requires versatile ...

  4. Reduced Metabolsim in Brain 'Control Networks' Following Cocaine-Cues Exposure in Female Cocaine Abusers

    SciTech Connect (OSTI)

    Volkow, N.D.; Wang, G.; Volkow, N.D.; Tomasi, D.; Wang, G.-J.; Fowler, J.S.; Telang, F.; Goldstein, R.Z.; Alia-Klein, N.; Wong, C.T.

    2011-03-01T23:59:59.000Z

    Gender differences in vulnerability for cocaine addiction have been reported. Though the mechanisms are not understood, here we hypothesize that gender differences in reactivity to conditioned-cues, which contributes to relapse, are involved. To test this we compared brain metabolism (using PET and {sup 18}FDG) between female (n = 10) and male (n = 16) active cocaine abusers when they watched a neutral video (nature scenes) versus a cocaine-cues video. Self-reports of craving increased with the cocaine-cue video but responses did not differ between genders. In contrast, changes in whole brain metabolism with cocaine-cues differed by gender (p<0.05); females significantly decreased metabolism (-8.6% {+-} 10) whereas males tended to increase it (+5.5% {+-} 18). SPM analysis (Cocaine-cues vs Neutral) in females revealed decreases in frontal, cingulate and parietal cortices, thalamus and midbrain (p<0.001) whereas males showed increases in right inferior frontal gyrus (BA 44/45) (only at p<0.005). The gender-cue interaction showed greater decrements with Cocaine-cues in females than males (p<0.001) in frontal (BA 8, 9, 10), anterior cingulate (BA 24, 32), posterior cingulate (BA 23, 31), inferior parietal (BA 40) and thalamus (dorsomedial nucleus). Females showed greater brain reactivity to cocaine-cues than males but no differences in craving, suggesting that there may be gender differences in response to cues that are not linked with craving but could affect subsequent drug use. Specifically deactivation of brain regions from 'control networks' (prefrontal, cingulate, inferior parietal, thalamus) in females could increase their vulnerability to relapse since it would interfere with executive function (cognitive inhibition). This highlights the importance of gender tailored interventions for cocaine addiction.

  5. Fractal characterization of fracture networks: An improved box-counting technique

    E-Print Network [OSTI]

    Perfect, Ed

    Fractal characterization of fracture networks: An improved box-counting technique Ankur Roy,1 fracture networks as fractals and estimating their fractal dimensions (D). If this analysis yields a power and r is the box size, then the network is considered to be fractal. However, researchers are divided

  6. TOWARDS IMPROVING NETWORK FLOW WATERMARKS USING THE REPEAT-ACCUMULATE CODES

    E-Print Network [OSTI]

    Borisov, Nikita

    TOWARDS IMPROVING NETWORK FLOW WATERMARKS USING THE REPEAT-ACCUMULATE CODES Amir Houmansadr the efficiency of network flow watermarks. In particular, we use the Repeat-Accumulate codes, a class of low simulation and discuss design tradeoffs. Index Terms-- Repeat-Accumulate codes, network flow watermarking

  7. alendronate improve metaphyseal: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    while the non-mathematical part can be described by a human language. We describe the mind-brain connection in our framework, and show that it resolves the problem of obtaining...

  8. Modelling Microtubules in the Brain as n-qudit Quantum Hopfield Network and Beyond

    E-Print Network [OSTI]

    Dayal Pyari Srivastava; Vishal Sahni; Prem Saran Satsangi

    2015-05-02T23:59:59.000Z

    The scientific approach to understand the nature of consciousness revolves around the study of human brain. Neurobiological studies that compare the nervous system of different species have accorded highest place to the humans on account of various factors that include a highly developed cortical area comprising of approximately 100 billion neurons, that are intrinsically connected to form a highly complex network. Quantum theories of consciousness are based on mathematical abstraction and Penrose-Hameroff Orch-OR Theory is one of the most promising ones. Inspired by Penrose-Hameroff Orch-OR Theory, Behrman et. al. (Behrman, 2006) have simulated a quantum Hopfield neural network with the structure of a microtubule. They have used an extremely simplified model of the tubulin dimers with each dimer represented simply as a qubit, a single quantum two-state system. The extension of this model to n-dimensional quantum states, or n-qudits presented in this work holds considerable promise for even higher mathematical abstraction in modelling consciousness systems.

  9. On Teaching Quality Improvement of a Mathematical Topic Using Artificial Neural Networks Modeling (With a Case Study)

    E-Print Network [OSTI]

    Spagnolo, Filippo

    431 On Teaching Quality Improvement of a Mathematical Topic Using Artificial Neural Networks inspired by simulation by Artificial Neural Networks (ANNs) applied recently for evaluation of phonics performance. Keywords: Artificial Neural Networks, Learning Performance Evaluation, Computer Aided Learning

  10. Improving the MAC Layer of Multi-Hop Networks Marceau Coupechoux

    E-Print Network [OSTI]

    Coupechoux, Marceau

    Improving the MAC Layer of Multi-Hop Networks Marceau Coupechoux Alcatel Research & Innovation and Institut Eurecom, France (marceau.coupechoux@alcatel.fr) Bruno Baynat Universite de Paris Pierre et Marie

  11. On Topology Improvement of a Packet Radio Network by Power Control

    E-Print Network [OSTI]

    Tseng, Yu-Chee

    1 On Topology Improvement of a Packet Radio Network by Power Control Chi­Fu Huang and Yu­Chee Tseng extensively studied. However, in this paper we observe that the power control issue has been ignored by most, packet radio network (PRN), power control, wireless communication. I. INTRODUCTION T HE Packet Radio

  12. Improving the Energy Balance of Field-based Routing in Wireless Sensor Networks

    E-Print Network [OSTI]

    Bustamante, Fabián E.

    Improving the Energy Balance of Field-based Routing in Wireless Sensor Networks Goce Trajcevski of the network merge into a single path. These path merging effects decrease significantly the energy balance deployments. When multiple sources transmit infor- mation simultaneously, together with energy balancing

  13. BLACK-BOX MODELLING OF HVAC SYSTEM: IMPROVING THE PERFORMANCES OF NEURAL NETWORKS

    E-Print Network [OSTI]

    Boyer, Edmond

    BLACK-BOX MODELLING OF HVAC SYSTEM: IMPROVING THE PERFORMANCES OF NEURAL NETWORKS Eric FOCK Ile de La Réunion - FRANCE ABSTRACT This paper deals with neural networks modelling of HVAC systems of HVAC system can be modelled using manufacturer design data presented as derived performance maps

  14. assistance improves intracorporeal: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    10 Provide Assistance to Improve Water Quality in Hood County Final Report Texas A&M University - TxSpace Summary: Service for funding the Providing Assistance to Improve...

  15. Abductive Network Committees for Improved Classification of Medical Data

    E-Print Network [OSTI]

    Abdel-Aal, Radwan E.

    for Applied Physical Sciences, Research Institute King Fahd University of Petroleum and Minerals, Dhahran the comprehensibility of neural networks, such as rule extraction [3], have been used in medicine [4]. Other limitations

  16. allergic rhinitis improves: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Bulletin No. 774 Genetic Improvement of Private Woodland Ecosystems in the Pacific Northwest Ronald... 3 What does genetic...

  17. attendance improves quality: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    any Zumba or Cardio Dance class Attend any class before 9:30 a 146 Improving Conifer Timber Quality Steering Group Kershope Progeny Trial and Renewable Energy Websites...

  18. acid improves global: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Global methodology in control architecture to improve mobile robot reliability B. Durand, K. Godary a global methodology devel- oped to increase the reliability of mobile...

  19. Improving Efficiency and Effectiveness of Multipath Routing in Computer Networks

    E-Print Network [OSTI]

    Lee, Yong Oh

    2012-07-16T23:59:59.000Z

    properties without oscillations, it has not been widely adopted. One of reasons was that the expected cost of keeping the link metrics updated at various nodes in the network. We proposed threshold-based updates to propagate the link state only when...

  20. An Advanced Channel Framework for Improved Underwater Acoustic Network Simulations

    E-Print Network [OSTI]

    Zhou, Shengli

    such as pollution, climate change and severe weather events is rapidly increasing. At the same time, as ocean underwater sensors, vehicles and devices together using acoustic communication. Network protocol development operation. However, acoustic communication performance is dynamic and dependent upon the environment

  1. auditory brain-stem response: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    auditory brain-stem response First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Auditory Brain Stem...

  2. antisense reduces blood-brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    antisense reduces blood-brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Studies in Blood-Brain...

  3. altered blood-brain barrier: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    altered blood-brain barrier First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Studies in Blood-Brain...

  4. activities improved water: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    by Improving Milking Center CiteSeer Summary: 1. Do you dispose of milking parlor waste (manure, feed solids, hoof dirt) or milk house wastewater (bulk tank rinses or cleaning...

  5. antivenom improves maternal: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    care for improved maternal and child health, but the practice and structures of womens health care have not yet evolved to reflect this knowledge. 1-3 Barriers include...

  6. alendronate treatment improves: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    This publication describes various kinds of systems and guides the homeowner in assessing... Harris, Bill L.; Hoffman, D.; Mazac Jr., F. J. 1997-08-29 26 Improving delivery...

  7. CONVERGING REDUNDANT SENSOR NETWORK INFORMATION FOR IMPROVED BUILDING CONTROL

    SciTech Connect (OSTI)

    Dale K. Tiller; Gregor P. Henze

    2004-11-01T23:59:59.000Z

    Knowing how many people occupy a building, and where they are located, is a key component of building energy management and security. Commercial, industrial and residential buildings often incorporate systems used to determine occupancy, however, current sensor technology and control algorithms limit the effectiveness of both energy management and security systems. This topical report describes results from the first phase of a project to design, implement, validate, and prototype new technologies to monitor occupancy, control indoor environment services, and promote security in buildings. Phase I of the project focused on instrumentation and data collection. In this project phase a new occupancy detection system was developed, commissioned and installed in a sample of private offices and open-plan office workstations. Data acquisition systems were developed and deployed to collect data on space occupancy profiles. Analysis tools based on Bayesian probability theory were applied to the occupancy data generated by the sensor network. The inference of primary importance is a probability distribution over the number of occupants and their locations in a building, given past and present sensor measurements. Inferences were computed for occupancy and its temporal persistence in individual offices as well as the persistence of sensor status. The raw sensor data were also used to calibrate the sensor belief network, including the occupancy transition matrix used in the Markov model, sensor sensitivity, and sensor failure models. This study shows that the belief network framework can be applied to the analysis of data streams from sensor networks, offering significant benefits to building operation compared to current practice.

  8. amino-terminal pro-brain natriuretic: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    amino-terminal pro-brain natriuretic First Page Previous Page 1 2 3 4 5 6 Next Page Last Page Topic Index 1 Natriuretic Peptide Testing in Primary Care CiteSeer Summary: Abstract:...

  9. The Economic Value of Improving the Reliability of Supply on a Bulk Power Transmission Network

    E-Print Network [OSTI]

    The Economic Value of Improving the Reliability of Supply on a Bulk Power Transmission Network Economics and Management and School of Electrical and Computer Engineering Cornell University Abstract, there is no established way of measuring the economic value of reliability, and as a result, regulators have adopted

  10. The Why UI: Using Goal Networks to Improve User Dustin A. Smith

    E-Print Network [OSTI]

    Herr, Hugh

    The Why UI: Using Goal Networks to Improve User Interfaces Dustin A. Smith MIT Media Lab 20 Ames St; Cambridge, MA 02139 dustin@media.mit.edu Henry Lieberman MIT Media Lab 20 Ames St; Cambridge, MA 02139 lieber@media.mit.edu ABSTRACT People interact with interfaces to accomplish goals, and knowl- edge about

  11. Improved Connectivity using Hybrid Uni/Omni-Directional Antennas in Sensor Networks

    E-Print Network [OSTI]

    Kwon, Ji Heon

    2008-05-27T23:59:59.000Z

    In partial fulfillment of the requirements of the UNIVERSITY UNDERGRADUATE RESEARCH FELLOWS April 2008 Major: Electrical Engineering ii ABSTRACT Improved Connectivity using Hybrid Uni/Omni-Directional Antennas in Sensor Networks (April 2008... environments: MATLAB, Maple Design automation tools: SIMULINK, PSpice, MAX+PLUS II LEADERSHIP & ACTIVITIES Student Engineers’ Council Undergraduate Curriculum Committee, Dept. of Computer Science Computing Service Advisory Committee, Dept. of Computer...

  12. Improved Power-Delay Trade-off in Wireless Ad Hoc Networks Using Opportunistic Routing

    E-Print Network [OSTI]

    Lee, Yong Hoon

    Improved Power-Delay Trade-off in Wireless Ad Hoc Networks Using Opportunistic Routing Won power- delay trade-off than the conventional routing while providing up to a logarithmic boost that the power can be reduced at the expense of increased delay for both scenarios, but better trade-off can

  13. Reactive power management of distribution networks with wind generation for improving voltage stability

    E-Print Network [OSTI]

    Pota, Himanshu Roy

    -loadability Reactive power margin Wind turbine a b s t r a c t This paper proposes static and dynamic VAR planningReactive power management of distribution networks with wind generation for improving voltage February 2013 Available online Keywords: Composite load Distributed generation D-STATCOM Q

  14. Mining Call and Mobility Data to Improve Paging Efficiency in Cellular Networks

    E-Print Network [OSTI]

    , Data Mining, CDMA 1. INTRODUCTION Location management is a key component in the operation of cellularMining Call and Mobility Data to Improve Paging Efficiency in Cellular Networks Hui Zang Sprint a different, data-driven approach in how we design and evaluate our solution. Specifically, we mine more than

  15. Improving Network Connection Locality on Multicore Systems Aleksey Pesterev Jacob Strauss Nickolai Zeldovich Robert T. Morris

    E-Print Network [OSTI]

    Gummadi, Ramakrishna

    Improving Network Connection Locality on Multicore Systems Aleksey Pesterev Jacob Strauss Nickolai Zeldovich Robert T. Morris MIT CSAIL Quanta Research Cambridge {alekseyp, nickolai, rtm}@csail.mit.edu jacob and that copies bear this notice and the full citation on the first page. To copy otherwise, to republish, to post

  16. alcohol-related brain damage: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    alcohol-related brain damage First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Proteomics of the human...

  17. ameliorates fractionated whole-brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    fractionated whole-brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 The purification and...

  18. affinity brain membrane-binding: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    affinity brain membrane-binding First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Membrane Binding of...

  19. auditory multi-class brain-computer: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    auditory multi-class brain-computer First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Adaptive...

  20. artery occlusion-induced brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    artery occlusion-induced brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 ScienceDaily (Jan. 30,...

  1. age-related cortical brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    age-related cortical brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Role of microstructure in...

  2. alleviates irradiation-induced brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    alleviates irradiation-induced brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1...

  3. acute post-traumatic brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    post-traumatic brain First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Attentional functioning in...

  4. addiction-related brain regions: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    addiction-related brain regions First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Estimating Uncertainty...

  5. acid mediates brain-derived: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    mediates brain-derived First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 DevelopmentPlasticityRepair...

  6. Early Brain Response to Low-Dose Radiation Exposure Involves Molecular Networks and Pathways Associated with Cognitive Functions, Advanced Aging and Alzheimer's Disease

    SciTech Connect (OSTI)

    Lowe, Xiu R; Bhattacharya, Sanchita; Marchetti, Francesco; Wyrobek, Andrew J.

    2008-06-06T23:59:59.000Z

    Understanding the cognitive and behavioral consequences of brain exposures to low-dose ionizing radiation has broad relevance for health risks from medical radiation diagnostic procedures, radiotherapy, environmental nuclear contamination, as well as earth orbit and space missions. Analyses of transcriptome profiles of murine brain tissue after whole-body radiation showed that low-dose exposures (10 cGy) induced genes not affected by high dose (2 Gy), and low-dose genes were associated with unique pathways and functions. The low-dose response had two major components: pathways that are consistently seen across tissues, and pathways that were brain tissue specific. Low-dose genes clustered into a saturated network (p < 10{sup -53}) containing mostly down-regulated genes involving ion channels, long-term potentiation and depression, vascular damage, etc. We identified 9 neural signaling pathways that showed a high degree of concordance in their transcriptional response in mouse brain tissue after low-dose radiation, in the aging human brain (unirradiated), and in brain tissue from patients with Alzheimer's disease. Mice exposed to high-dose radiation did not show these effects and associations. Our findings indicate that the molecular response of the mouse brain within a few hours after low-dose irradiation involves the down-regulation of neural pathways associated with cognitive dysfunctions that are also down regulated in normal human aging and Alzheimer's disease.

  7. Improving performance of transmission control protocol (TCP) over mobile wireless networks

    E-Print Network [OSTI]

    Bakshi, Bikram Singh

    1996-01-01T23:59:59.000Z

    of this research, we study thc eHect of (a) burst errors on wirelcss links, (b) packet size variation on the ivired network, (c) local error recovery by the base station, and (d) explicit feedback by the base station, on the performance of TCP over wireless... networks. It is shown that the performance of TCP is sensitive to the packet size, and that choosing a 'good' packet size results in performance improve- ments. While local recovery by the base station using link-level retransmissions is also found...

  8. Power Control MAC Protocol Analysis and Improvement for Ad Hoc Networks Ping Ding, JoAnne Holliday, Aslihan Celik

    E-Print Network [OSTI]

    Holliday, JoAnne

    Power Control MAC Protocol Analysis and Improvement for Ad Hoc Networks Ping Ding, JoAnne Holliday power control protocols have been proposed to address the limited power supplies in ad hoc networks in the same transmission. In this paper, we review different power control MAC protocols, and analyze

  9. STANDARD BIG BANG NUCLEOSYNTHESIS UP TO CNO WITH AN IMPROVED EXTENDED NUCLEAR NETWORK

    SciTech Connect (OSTI)

    Coc, Alain [Centre de Spectrometrie Nucleaire et de Spectrometrie de Masse (CSNSM), CNRS/IN2P3, Universite Paris Sud, UMR 8609, Batiment 104, F-91405 Orsay Campus (France); Goriely, Stephane; Xu, Yi [Institut d'Astronomie et d'Astrophysique, Universite Libre de Bruxelles, CP 226, Boulevard du Triomphe, B-1050 Bruxelles (Belgium); Saimpert, Matthias; Vangioni, Elisabeth [Institut d'Astrophysique de Paris, UMR 7095 CNRS, Universite Pierre et Marie Curie, 98 bis Boulevard Arago, Paris 75014 (France)

    2012-01-10T23:59:59.000Z

    Primordial or big bang nucleosynthesis (BBN) is one of the three strong pieces of evidence for the big bang model together with the expansion of the universe and cosmic microwave background radiation. In this study, we improve the standard BBN calculations taking into account new nuclear physics analyses and enlarge the nuclear network up to sodium. This is, in particular, important to evaluate the primitive value of CNO mass fraction that could affect Population III stellar evolution. For the first time we list the complete network of more than 400 reactions with references to the origin of the rates, including Almost-Equal-To 270 reaction rates calculated using the TALYS code. Together with the cosmological light elements, we calculate the primordial beryllium, boron, carbon, nitrogen, and oxygen nuclei. We performed a sensitivity study to identify the important reactions for CNO, {sup 9}Be, and boron nucleosynthesis. We re-evaluated those important reaction rates using experimental data and/or theoretical evaluations. The results are compared with precedent calculations: a primordial beryllium abundance increase by a factor of four compared to its previous evaluation, but we note a stability for B/H and for the CNO/H abundance ratio that remains close to its previous value of 0.7 Multiplication-Sign 10{sup -15}. On the other hand, the extension of the nuclear network has not changed the {sup 7}Li value, so its abundance is still 3-4 times greater than its observed spectroscopic value.

  10. Fast Sparsely Synchronized Brain Rhythms in A Scale-Free Neural Network

    E-Print Network [OSTI]

    Kim, Sang-Yoon

    2015-01-01T23:59:59.000Z

    We consider a directed Barab\\'{a}si-Albert scale-free network model with symmetric preferential attachment with the same in- and out-degrees, and study emergence of sparsely synchronized rhythms for a fixed attachment degree in an inhibitory population of fast spiking Izhikevich interneurons. For a study on the fast sparsely synchronized rhythms, we fix $J$ (synaptic inhibition strength) at a sufficiently large value, and investigate the population states by increasing $D$ (noise intensity). For small $D$, full synchronization with the same population-rhythm frequency $f_p$ and mean firing rate (MFR) $f_i$ of individual neurons occurs, while for sufficiently large $D$ partial synchronization with $f_p > {\\langle f_i \\rangle}$ ($\\langle f_i \\rangle$: ensemble-averaged MFR) appears due to intermittent discharge of individual neurons; particularly, the case of $f_p > 4 {\\langle f_i \\rangle}$ is referred to as sparse synchronization. Only for the partial and sparse synchronization, MFRs and contributions of indiv...

  11. Foundations of Artificial Intelligence Neural Networks

    E-Print Network [OSTI]

    Qu, Rong

    Foundations of Artificial Intelligence Neural Networks Building Artificial Brains #12;Background Session 2 Software Demonstrations Real World Applications #12;Artificial Neural Networks ... consists to operate. Wiki #12;Relationship between Artificial Neural Networks & the Human Brain Neural networks

  12. The Social Brain; An Investigation into Total Social Network Size and Relationship Closeness within a Distinct Human Population. 

    E-Print Network [OSTI]

    Brown, Philippa

    2008-06-27T23:59:59.000Z

    ) ‘social intelligence’ (emergent from ‘general intelligence’) was found to correlate with total social network size in humans: (r = .225, p networks size was established (r...

  13. A Study of the Energy Saving and Capacity Improvement Potential of Power Control in Multi-hop Wireless Networks

    E-Print Network [OSTI]

    Hwu, Wen-mei W.

    A Study of the Energy Saving and Capacity Improvement Potential of Power Control in Multi- This study investigates the potential of using transmission power control in wireless packet networks with differing number of hops between source and destination. Here we exploit the benefits of power control

  14. Improved Connectivity using Hybrid Uni/Omni-Directional Antennas in Sensor Networks 

    E-Print Network [OSTI]

    Kwon, Ji Heon

    2008-05-27T23:59:59.000Z

    Connectivity in sensor networks is an important metric that describes the capability of networks to be able to report sensed information. The ability of member nodes to communicate with each other and collectively report data largely depends...

  15. The Noisy Brain: Stochastic Dynamics as a Principle of

    E-Print Network [OSTI]

    Rolls, Edmund T.

    The Noisy Brain: Stochastic Dynamics as a Principle of Brain Function Edmund T. Rolls Oxford Centre random spiking times of individual neurons produce a source of noise in the brain. The aim of this book is to consider the effects of this and other noise on brain pro- cessing. We show that in cortical networks

  16. Opportunities to Save Energy and Improve Comfort by Using Wireless Sensor Networks in Buildings 

    E-Print Network [OSTI]

    Wang, D.; Arens, E.; Federspiel, C.

    2003-01-01T23:59:59.000Z

    This paper discusses how intensive information technology can affect future building operation. Recent breakthroughs in wireless sensor network technology will permit 1) highly flexible location of sensors, 2) increased sensing density and variety...

  17. 787 mid-body job precedence networks for improving production rate

    E-Print Network [OSTI]

    Chen, Jason L., 1979-

    2012-01-01T23:59:59.000Z

    In a complex manufacturing environment, generating schedules, identifying deviations, and recovering from delays have a significant impact on total operational performance. At Boeing's 787 plant, a precedence network was ...

  18. Asynchronous Bypass Channels Improving Performance for Multi-synchronous Network-on-chips

    E-Print Network [OSTI]

    Jain, Tushar Naveen Kumar

    2011-10-21T23:59:59.000Z

    microarchitecture which offers superior performance versus typical synchroniz- ing router designs. Our approach features Asynchronous Bypass Channels (ABCs) at intermediate nodes thus avoiding synchronization delay. We also propose a new network topology and routing...

  19. Congestion on the Internet : operator responses, economic analysis, and improving the network architecture

    E-Print Network [OSTI]

    Bauer, Steven J. (Steven Joseph), 1976-

    2008-01-01T23:59:59.000Z

    Our thesis presents the results of monitoring traffic management techniques of network providers. We find that in addition to complete blocking of traffic flows on some transport layer ports, providers are also actively ...

  20. An examination of professional learning in two districts : comparing the quality and quantity of network structure for improved achievement

    E-Print Network [OSTI]

    Bloomberg, Paul J.

    2012-01-01T23:59:59.000Z

    perceptions of administrators in the network. Interview wereoffice administrators are central in the network as shown bysite administrator) were isolates in this network, meaning

  1. Network protocol changes can improve DisCom WAN performance : evaluating TCP modifications and SCTP in the ASC tri-lab environment.

    SciTech Connect (OSTI)

    Tolendino, Lawrence F.; Hu, Tan Chang

    2005-06-01T23:59:59.000Z

    The Advanced Simulation and Computing (ASC) Distance Computing (DisCom) Wide Area Network (WAN) is a high performance, long distance network environment that is based on the ubiquitous TCP/IP protocol set. However, the Transmission Control Protocol (TCP) and the algorithms that govern its operation were defined almost two decades ago for a network environment vastly different from the DisCom WAN. In this paper we explore and evaluate possible modifications to TCP that purport to improve TCP performance in environments like the DisCom WAN. We also examine a much newer protocol, SCTP (Stream Control Transmission Protocol) that claims to provide reliable network transport while also implementing multi-streaming, multi-homing capabilities that are appealing in the DisCom high performance network environment. We provide performance comparisons and recommendations for continued development that will lead to network communications protocol implementations capable of supporting the coming ASC Petaflop computing environments.

  2. Imaging - Clearer brain scans ... | ornl.gov

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Imaging - Clearer brain scans ... A clever signal noise reduction strategy developed by a team that includes Oak Ridge National Laboratory's Ben Lawrie could dramatically improve...

  3. On Improving Data Accessibility in Storage Based Sensor Networks Tan Apaydin Serdar Vural Prasun Sinha

    E-Print Network [OSTI]

    Sinha, Prasun

    Sinha Department of CSE Department of ECE Department of CSE The Ohio State University The Ohio State University The Ohio State University apaydin@cse.ohio-state.edu vurals@ece.osu.edu prasun@cse.ohio to originate from any node in the network. However, limited amount and fast depletion of energy resources

  4. Not Quickly, Just in Time: Improving the Timeliness and Reliability of Control Traffic in Utility Networks

    E-Print Network [OSTI]

    Correia, Miguel

    networks, that interconnect the CI facil- ities (e.g., transformation substations). This communication company (e.g., transformation substations), but in a distributed way with systems and applications often] and unavailability may become even more frequent due to denial-of-service attacks (DoS), e.g., ex- ecuted as cyber

  5. Does brain activity stem from high-dimensional chaotic dynamics? Evidence from the human electroencephalogram, cat cerebral cortex and artificial neuronal networks

    E-Print Network [OSTI]

    Sami El Boustani; Alain Destexhe

    2009-04-27T23:59:59.000Z

    Nonlinear time series analyses have suggested that the human electroencephalogram (EEG) may share statistical and dynamical properties with chaotic systems. During slow-wave sleep or pathological states like epilepsy, correlation dimension measurements display low values, while in awake and attentive subjects, there is not such low dimensionality, and the EEG is more similar to a stochastic variable. We briefly review these results and contrast them with recordings in cat cerebral cortex, as well as with theoretical models. In awake or sleeping cats, recordings with microelectrodes inserted in cortex show that global variables such as local field potentials (local EEG) are similar to the human EEG. However, in both cases, neuronal discharges are highly irregular and exponentially distributed, similar to Poisson stochastic processes. To attempt reconcile these results, we investigate models of randomly-connected networks of integrate-and-fire neurons, and also contrast global (averaged) variables, with neuronal activity. The network displays different states, such as "synchronous regular" (SR) or "asynchronous irregular" (AI) states. In SR states, the global variables display coherent behavior with low dimensionality, while in AI states, the global activity is high-dimensionally chaotic with exponentially distributed neuronal discharges, similar to awake cats. Scale-dependent Lyapunov exponents and epsilon-entropies show that the seemingly stochastic nature at small scales (neurons) can coexist with more coherent behavior at larger scales (averages). Thus, we suggest that brain activity obeys similar scheme, with seemingly stochastic dynamics at small scales (neurons), while large scales (EEG) display more coherent behavior or high-dimensional chaos.

  6. Improving the Delivery of Camptothecin through the Blood-Brain Barrier via Modulation of Paracellular Pathway using E-Cadherin Peptide

    E-Print Network [OSTI]

    Tabanor, Kayann

    2014-12-31T23:59:59.000Z

    product CPT from harvested brain, followed by detection using LC-MS/MS. The extraction and LC-MS/MS detection methods have been successfully developed to detect 0.25 and 17 ng/mL CPT and CPT-Glu respectively. Both CPT-Glu and CPT were successfully detected...

  7. Exploiting Overhearing: Flow-Aware Routing for Improved Lifetime in Ad Hoc Networks

    E-Print Network [OSTI]

    Mans, Bernard

    of the schemes claiming to be energy-efficient neglect this cost by only focusing on energy costs due to local whether a more traffic-conscious routing scheme works better in improving the energy-efficiency Shrestha, Bernard Mans Department of Computing, Macquarie University Sydney, NSW 2109 Australia Email

  8. An evaluation of energy storage techniques for improving ride-through capability for sensitive customers on underground networks

    SciTech Connect (OSTI)

    Braz, A.; Hofmann, P.; Mauro, R. [Con Edison, New York, NY (United States); Melhorn, C.J. [Electrotek Concepts, Inc., Knoxville, TN (United States)

    1995-12-31T23:59:59.000Z

    Most Con Edison customers are supplied through extensive secondary network systems. These customers do not experience interruptions or outages except under very rare circumstances. This is a significant advantage for these customers since they do not normally need to apply conventional UPS systems for protection of critical loads against outages. However, voltage sags, which occur whenever there is a fault on the power system, can cause dropout or mis-operation of sensitive equipment. Some type of protection may be needed for these loads to provide ride through support during voltage sags. This paper describes the methodology used in a research project sponsored by EPRI and Con Edison to evaluate the need for voltage sag ride through improvement for selected customers. Technologies that can supply the required ride through and application considerations were evaluated. Two case studies are presented to illustrate the methodology used to perform the evaluations.

  9. Brain-Computer Interfaces

    E-Print Network [OSTI]

    Aggarwal, Khushbu

    2009-01-01T23:59:59.000Z

    I \\ November 16, 2008). CNN. ’Brain’ in a dish ?ies ?ightREFERENCES Adams, Ray. Brain Computer Interfaces: Psychologyaccessed Biever, Celeste. Brain cells in a dish ?y ?ghter

  10. Cohort-level brain mapping: learning cognitive atoms to single out specialized regions

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Cohort-level brain mapping: learning cognitive atoms to single out specialized regions G. Varoquaux, France Abstract. Functional Magnetic Resonance Imaging (fMRI) studies map the human brain by testing specialized brain regions and networks. The number of functional networks extracted is limited by the number

  11. SPARTA+: a modest improvement in empirical NMR chemical shift prediction by means of an artificial neural network

    E-Print Network [OSTI]

    Bax, Ad

    of an artificial neural network Yang Shen · Ad Bax Received: 4 June 2010 / Accepted: 30 June 2010 / Published a new chemical shift prediction program, SPARTA?, which is based on artificial neural networking. The neural network is trained on a large carefully pruned database, containing 580 proteins for which high

  12. anatomically modern humans: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Last Page Topic Index 1 HIERARCHICAL TOPOLOGICAL NETWORK ANALYSIS OF ANATOMICAL HUMAN BRAIN CONNECTIVITY AND Mathematics Websites Summary: HIERARCHICAL TOPOLOGICAL NETWORK...

  13. neuroscience / brain & mind neuroscience / brain & mind

    E-Print Network [OSTI]

    Denham, Graham

    neuroscience / brain & mind #12;neuroscience / brain & mind Investment Construction of new Centre for Brain & Mind $3.6million External funding for researchers $60million Provincial investment in a 3T and one of three 7T MRI in the world $12million #12;neuroscience / brain & mind Recruitment and Building

  14. Parameter assignment for improved connectivity and security in randomly deployed wireless sensor networks via hybrid omni/uni-directional antennas

    E-Print Network [OSTI]

    Shankar, Sonu

    2009-05-15T23:59:59.000Z

    ,omni-directional antennas have been used for communication in wireless sensor net-works. In this thesis, a hybrid communication model is presented where-in, nodes ina network are capable of both omni-directional and uni-directional communication.The eect of such a model...

  15. A policy letter. DG-GRID Improving distribution network regulation for enhancing the share of sustainable distributed generation in Europe

    E-Print Network [OSTI]

    expenditures (CAPEX) and operational expenditures (OPEX), mainly related to network investment and energy for incremental CAPEX & OPEX due to DG, should be designed taking into account the particular DSO regulatory

  16. Redesigning and improving the efficiency of bus transit networks using automatically collected data : the case of Gipuzkoa, Spain

    E-Print Network [OSTI]

    Gutiérrez de Quevedo Aguerrebere, Carlos

    2012-01-01T23:59:59.000Z

    Transit agencies around the world are adopting Automatically Data Collection Systems (ADCS) to carry out standard tasks in the management of their networks. Many of these agencies have taken further steps in the use of ...

  17. Vortices in Brain waves

    E-Print Network [OSTI]

    Freeman, Walter J III; Vitiello, Giuseppe

    2010-01-01T23:59:59.000Z

    Burke and M. D. Holmes, Human Brain Mapping 19(4), 248 7. W.20. W. J. Freeman, How Brains Make Up Their Minds (Columbiaand K. Yasue, Quantum Brain Dynamics and Consciousness (John

  18. Singing the Brain Electric

    E-Print Network [OSTI]

    Chua, Grace (Grace W. J.)

    2008-01-01T23:59:59.000Z

    Singing the Brain Electric Brain pacemakers, scientists have found, can treat depression by correcting neural circuitry gone haywire. This thesis examines how such technology - a technique known as deep-brain stimulation, ...

  19. Gene expression abnormalities in the autistic brain

    E-Print Network [OSTI]

    Chow, Maggie Lok Mun

    2011-01-01T23:59:59.000Z

    13 Early Brain Overgrowth13 Discontinuous brainpostmortem brain ______________________________________ 33

  20. Biophysically Accurate Brain Modeling and Simulation using Hybrid MPI/OpenMP Parallel Processing

    E-Print Network [OSTI]

    Hu, Jingzhen

    2012-07-16T23:59:59.000Z

    In order to better understand the behavior of the human brain, it is very important to perform large scale neural network simulation which may reveal the relationship between the whole network activity and the biophysical dynamics of individual...

  1. 2005 International Conference on Wireless Networks, Communications and Mobile Computing Improving TCP Throughput over Lossy Links Using

    E-Print Network [OSTI]

    Atiquzzaman, Mohammed

    TCP Throughput over Lossy Links Using Protocol-Level Speculations Haowei Bai Honeywell Labs 3660- The degradation of Transport Control Protocol (TCP) throughput in networks with lossy links is mainly due to processor performance degradation due to control hazards in CPU design. First, two types of loss events

  2. Using Knowledge-Based Neural Networks to Improve Algorithms: Refining the Chou-Fasman Algorithm for Protein Folding

    E-Print Network [OSTI]

    Maclin, Rich

    for Protein Folding Richard Maclin Jude W. Shavlik Computer Sciences Dept. University of Wisconsin 1210 W learning Theory refinement Neural networks Finite-state automata Protein folding Chou-Fasman algorithm-Fasman algorithm, a method for predicting how globular proteins fold. Empirical evidence shows

  3. Human Functional Brain Imaging

    E-Print Network [OSTI]

    Rambaut, Andrew

    Human Functional Brain Imaging 1990­2009 September 2011 Portfolio Review Summary Brain Imaging #12 Dale ­ one of our first Trustees. Understanding the brain remains one of our key strategic aims today three-fold: · to identify the key landmarks and influences on the human functional brain imaging

  4. ANNUAL REPORT National Brain Research Centre

    E-Print Network [OSTI]

    Dhingra, Narender K.

    1 ANNUAL REPORT 2003-2004 National Brain Research Centre Manesar, India #12;2 Table of Contents in neuroscience. Promoting neuroscience in India through networking among institutions across the country. If we can fathom how children learn, our education policy could be strengthened with a new understanding

  5. Training Algorithms for Networks of Spiking Neurons

    E-Print Network [OSTI]

    Singh, Nityendra

    2014-12-08T23:59:59.000Z

    Neural networks represent a type of computing that is based on the way that the brain performs computations. Neural networks are good at fitting non-linear functions and recognizing patterns. It is believed that biological neurons work similar...

  6. Mechanisms of brain ventricle development

    E-Print Network [OSTI]

    Lowery, Laura Anne

    2008-01-01T23:59:59.000Z

    The brain ventricles are a conserved system of fluid-filled cavities within the brain that form during the earliest stages of brain development. Abnormal brain ventricle development has been correlated with neurodevelopmental ...

  7. Brain Prostheses as a Dynamic System (Immortalizing the Human Brain?)

    E-Print Network [OSTI]

    Vadim Astakhov; Tamara Astakhova

    2007-05-17T23:59:59.000Z

    Interest in development of brain prostheses, which might be proposed to recover mental functions lost due to neuron-degenerative disease or trauma, requires new methods in molecular engineering and nanotechnology to build artificial brain tissues. We develop a Dynamic Core model to analyze complexity of damaged biological neural network as well as transition and recovery of the system functionality due to changes in the system environment. We provide a method to model complexity of physical systems which might be proposed as an artificial tissue or prosthesis. Delocalization of Dynamic Core model is developed to analyze migration of mental functions in dynamic bio-systems which undergo architecture transition induced by trauma. Term Dynamic Core is used to define a set of causally related functions and Delocalization is used to describe the process of migration. Information geometry and topological formalisms are proposed to analyze information processes. A holographic model is proposed to construct dynamic environment with self-poetic Dynamic Core which preserve functional properties under transition from one host to another. We found statistical constraints for complex systems which conserve a Dynamic Core under environment transition. Also we suggest those constraints might provide recommendations for nanotechnologies and tissue engineering used in development of an artificial brain tissue.

  8. I am John's Brain 

    E-Print Network [OSTI]

    Clark, Andy

    1995-01-01T23:59:59.000Z

    The brain and its "agent" debate the provenance of thoughts in the charming language of an old Readers Digest article.

  9. NAVIGATING THE BRAIN'S MYSTERIES

    E-Print Network [OSTI]

    C C C A A A A G A G G D D D D D F D F F F H H H E E E E FHE E B B B C E B NAVIGATING THE BRAIN of the brain-- one that shows its complex trafficking across trillions of neuronal connections. Addressing: outlining "the next great American project," the BRAIN (Brain Research through Advancing Innovative

  10. Network coding for robust wireless networks

    E-Print Network [OSTI]

    Kim, MinJi, Ph. D. Massachusetts Institute of Technology

    2012-01-01T23:59:59.000Z

    Wireless networks and communications promise to allow improved access to services and information, ubiquitous connectivity, and mobility. However, current wireless networks are not well-equipped to meet the high bandwidth ...

  11. Human Functional Brain Imaging

    E-Print Network [OSTI]

    Rambaut, Andrew

    Human Functional Brain Imaging 1990­2009 September 2011 Portfolio Review #12;2 | Portfolio Review: Human Functional Brain ImagingThe Wellcome Trust is a charity registered in England and Wales, no's role in supporting human functional brain imaging and have informed `our' speculations for the future

  12. Artificial Neural Network Portion of Coil Study

    E-Print Network [OSTI]

    Putten, Peter van der

    Artificial Neural Network Portion of Coil Study LTC William M. Crocoll School of Systems TO ARTIFICIAL NEURAL NETWORKS A neural network is a massively parallel system comprised of many highly of the brain (Dayhoff, 1990). A major task for a neural network is to learn and maintain a model of the world

  13. The Brain Basis of Emotions 1 BRAIN BASIS OF EMOTION

    E-Print Network [OSTI]

    Barrett, Lisa Feldman

    The Brain Basis of Emotions 1 BRAIN BASIS OF EMOTION The brain basis of emotion: A meta, Building 149 Charlestown, MA 02129 lindqukr@nmr.mgh.harvard.edu #12;The Brain Basis of Emotions 2 Abstract Researchers have wondered how the brain creates emotions since the early days of psychological science

  14. atherosclerotic lesions imaging: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    non-subjective quantitative analysis, (more) Li, Jialin 2010-01-01 46 Classification of brain compartments and head injury lesions by neural networks applied to magnetic...

  15. Bruce Braine VP, Strategic Policy Analysis

    E-Print Network [OSTI]

    Howat, Ian M.

    5/16/2014 1 Bruce Braine VP, Strategic Policy Analysis American Electric Power Thursday, May 15, 2014 Power Infrastructure: Improving Reliability and Resiliency 2 · 5.3 Million customers · 11 States regulations. 4 #12;5/16/2014 3 Power Infrastructure · Ongoing threats to power infrastructure and reliability

  16. Recognizing targets from infrared intensity scan patterns using artificial neural networks

    E-Print Network [OSTI]

    Barshan, Billur

    Recognizing targets from infrared intensity scan patterns using artificial neural networks Tayfun complicating the localization and recognition process. We employ artificial neural networks to deter- mine differentiation; artificial neural networks; optimal brain surgeon; pattern recognition. Paper 080450R received

  17. Sandia uses supercomputer simulations to improve helmets | National...

    National Nuclear Security Administration (NNSA)

    to improve helmets NNSA Blog Supercomputer simulations of blast waves on the brain are being compared with clinical studies of veterans suffering from mild traumatic...

  18. Artificial Neural Network Circuit for Spectral Pattern Recognition

    E-Print Network [OSTI]

    Rasheed, Farah

    2013-09-04T23:59:59.000Z

    Artificial Neural Networks (ANNs) are a massively parallel network of a large number of interconnected neurons similar to the structure of biological neurons in the human brain. ANNs find applications in a large number of fields, from pattern...

  19. Spatiotemporal brain imaging and modeling

    E-Print Network [OSTI]

    Lin, Fa-Hsuan, 1972-

    2004-01-01T23:59:59.000Z

    This thesis integrates hardware development, data analysis, and mathematical modeling to facilitate our understanding of brain cognition. Exploration of these brain mechanisms requires both structural and functional knowledge ...

  20. AAnnnnuuaall NNeeuurrooeennggiinneeeerriinngg SSyymmppoossiiuumm PPrrooggrraamm "The Ins and Outs of the Brain"

    E-Print Network [OSTI]

    Weiblen, George D

    of the Brain" February 16, 2012 Mississippi Room, 3rd Floor, Coffman Union 8:10 ­ 8:30 Networking (Coffee, Center for Neuroengineering 8:50 ­ 10:10 Session 1: Imaging and Decoding of the Brain (A) Moderator: Bin 9:10 ­ 9:30 In vivo study of brain energy and function Wei Chen, Radiology 9:30 ­ 9:50 Can we

  1. The Brain, the Broken Brain & the Neural Biology of Language

    E-Print Network [OSTI]

    Collar, Juan I.

    The Brain, the Broken Brain & the Neural Biology of Language Presenter: Steven Small Time & Date.maproom.com )1949 N. Hoyne Café Email list https://cfcpwork.uchicago.edu/mailman/listinfo/cafe #12;The Brain, the Broken Brain & the Neural Biology of Language Presenter: Steven Small Time & Date: 7-9 PM Monday

  2. THE GEOMETRY OF NETWORKS OLIVER KNILL

    E-Print Network [OSTI]

    Knill, Oliver

    in fashion? It is not only that the world wide web, social networks, research on proteins, or nano, nanotechnology, web tomography, social networks or loop quantum gravity. In math- ematics it allows to look · word connections and associations · the brain as a neural network · artificial intelligence questions

  3. Gamma Knife Radiosurgery for Brain Metastases From Primary Breast Cancer

    SciTech Connect (OSTI)

    Kased, Norbert, E-mail: Norbert.Kased@ucsf.ed [Department of Radiation Oncology, University of California, San Francisco, School of Medicine, San Francisco, CA (United States); Binder, Devin K. [Department of Neurological Surgery, University of California, San Francisco, School of Medicine, San Francisco, CA (United States); McDermott, Michael W. [Department of Radiation Oncology, University of California, San Francisco, School of Medicine, San Francisco, CA (United States); Department of Neurological Surgery, University of California, San Francisco, School of Medicine, San Francisco, CA (United States); Nakamura, Jean L.; Huang, Kim [Department of Radiation Oncology, University of California, San Francisco, School of Medicine, San Francisco, CA (United States); Berger, Mitchel S. [Department of Neurological Surgery, University of California, San Francisco, School of Medicine, San Francisco, CA (United States); Wara, William M.; Sneed, Penny K. [Department of Radiation Oncology, University of California, San Francisco, School of Medicine, San Francisco, CA (United States)

    2009-11-15T23:59:59.000Z

    Purpose: The relative roles of stereotactic radiosurgery (SRS) vs. whole brain radiotherapy (WBRT) in the treatment of patients with brain metastases from breast cancer remain undefined. In this study, we reviewed our experience with these patients. Materials and Methods: We retrospectively reviewed all patients treated between 1991 and 2005 with Gamma Knife SRS for brain metastases from breast cancer. The actuarial survival and freedom from progression endpoints were calculated using the Kaplan-Meier method. Results: Between 1991 and 2005, 176 patients underwent SRS for brain metastases from breast cancer. The median survival time was 16.0 months for 95 newly diagnosed patients and 11.7 months for 81 patients with recurrent brain metastases. In the newly diagnosed patients, omission of upfront WBRT did not significantly affect the MST (p = .20), brain freedom from progression (p = .75), or freedom from new brain metastases (p = .83). Longer survival was associated with age <50 years, Karnofsky performance score >=70, primary tumor control, estrogen receptor positivity, and Her2/neu overexpression. No association was found between the number of treated brain metastases and the survival time. Conclusion: We have described prognostic factors for breast cancer patients treated with SRS for newly diagnosed or recurrent brain metastases. Most patient subsets had a median survival time of >=11 months. Unexpectedly, upfront WBRT did not appear to improve brain freedom from progression, and a larger number of brain metastases was not associated with a shorter survival time. Breast cancer might be distinct from other primary sites in terms of prognostic factors and the roles of WBRT and SRS for brain metastases.

  4. Brain Networks, Nature and Neighborhoods: Quantifying Internal...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    BuildingRoom: Searle 240A, 5735 S. Ellis Avenue - This talk will be broadcast via Blue Jeans (see new Info below) Location: University of Chicago Speaker(s): Marc G. Berman...

  5. NDN, VOLUME TRANSMISSION, AND SELF-ORGANIZATION IN BRAIN DYNAMICS

    E-Print Network [OSTI]

    Freeman, Walter J.

    with neural network theory as proposed by Hebb in his 1949 classic The Organization of Behavior where heNDN, VOLUME TRANSMISSION, AND SELF- ORGANIZATION IN BRAIN DYNAMICS WALTER J FREEMAN Department chemical gradients; and order parameters that control self-organization of large populations of neurons

  6. UCIT Data Network Standards Campus Wireless Network Standard

    E-Print Network [OSTI]

    Habib, Ayman

    UCIT Data Network Standards Campus Wireless Network Standard Classification IT Infrastructure Table.1. Standardization of the U of C's 802.11 wireless networks and frequency bands is required to insure availability of the wireless network to the campus community. Standards of use will improve the wireless service and help

  7. Link Loss Inference in Wireless Sensor Networks with Randomized Network Coding

    E-Print Network [OSTI]

    Wong, Vincent

    Link Loss Inference in Wireless Sensor Networks with Randomized Network Coding Vahid Shah that randomized network coding can improve the reliability of wireless sensor networks with lossy links. With network coding, the loss rate of a chosen path in a wireless sensor network is the maximum link loss rate

  8. Children's Brain Development Benefits from Longer Gestation

    E-Print Network [OSTI]

    2011-01-01T23:59:59.000Z

    Mapping of the Human Brain. NeuroImage, Sendai, Japan.2005). Regional deficits in brain volume in schizophrenia: areso- nance imaging of brain development in premature and

  9. Genomic mosaicism in the human brain

    E-Print Network [OSTI]

    Westra, Jurjen Willem

    2008-01-01T23:59:59.000Z

    Zlokovic BV (2008) The blood-brain barrier in health andmosaicism in the human brain ………………………………………. Chapter Threethe Alzheimer’s disease brain ………………………………. Chapter Five DNA

  10. MR imaging of the fetal brain

    E-Print Network [OSTI]

    Glenn, Orit A.

    2010-01-01T23:59:59.000Z

    development of the fetal brain by MRI. Semin Perinatol 33:determination in normal fetal brain: a prenatal MR imagingin intrauterine fetal brain development. In: Abstracts of

  11. Network Management Network Management

    E-Print Network [OSTI]

    that pertain to the operation, administration, maintenance, and provisioning of networked systems · Operation deals with keeping the network up (and the service provided by the network) · Administration involvesNetwork Management Pag. 1 Network Management Andrea Bianco Telecommunication Network Group Network

  12. amacrine cell network: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    but also helps improve the QoS of the core network and saves the carriers' OPEX and CAPEX on their core networks. Ouyang, Ye; 10.5121ijngn.2010.2105 2010-01-01 64 The...

  13. Shorter-Course Whole-Brain Radiotherapy for Brain Metastases in Elderly Patients

    SciTech Connect (OSTI)

    Rades, Dirk, E-mail: rades.dirk@gmx.net [Department of Radiation Oncology, University Hospital Schleswig-Holstein, Lubeck (Germany); Department of Radiation Oncology, University Hospital Hamburg-Eppendorf, Hamburg (Germany); Evers, Jasmin N. [Department of Radiation Oncology, University Hospital Schleswig-Holstein, Lubeck (Germany); Veninga, Theo [Department of Radiotherapy, Dr. Bernard Verbeeten Institute, Tilburg (Netherlands); Stalpers, Lukas J.A. [Department of Radiotherapy, Academic Medical Center, Amsterdam (Netherlands); Lohynska, Radka [Department of Radiation Oncology, University Hospital, Prague (Czech Republic); Schild, Steven E. [Department of Radiation Oncology, Mayo Clinic Scottsdale, Arizona (United States)

    2011-11-15T23:59:59.000Z

    Purpose: Many patients with brain metastases receive whole-brain radiotherapy (WBRT) alone. Using 10 Multiplication-Sign 3 Gy in 2 weeks is the standard regimen in most centers. Regarding the extraordinarily poor survival prognosis of elderly patients with multiple brain metastases, a shorter WBRT regimen would be preferable. This study compared 10 Multiplication-Sign 3 Gy with 5 Multiplication-Sign 4 Gy in elderly patients ({>=}65 years). Methods and Materials: Data from 455 elderly patients who received WBRT alone for brain metastases were retrospectively analyzed. Survival and local (= intracerebral) control of 293 patients receiving 10 Multiplication-Sign 3 Gy were compared with 162 patients receiving 5 Multiplication-Sign 4 Gy. Eight additional potential prognostic factors were investigated including age, gender, Karnofsky performance score (KPS), primary tumor, number of brain metastases, interval from tumor diagnosis to WBRT, extracerebral metastases, and recursive partitioning analysis (RPA) class. Results: The 6-month overall survival rates were 29% after 5 Multiplication-Sign 4 Gy and 21% after 10 Multiplication-Sign 3 Gy (p = 0.020). The 6-month local control rates were 12% and 10%, respectively (p = 0.32). On multivariate analysis, improved overall survival was associated with KPS {>=} 70 (p < 0.001), only one to three brain metastases (p = 0.029), no extracerebral metastasis (p = 0.012), and lower RPA class (p < 0.001). Improved local control was associated with KPS {>=} 70 (p < 0.001), breast cancer (p = 0.029), and lower RPA class (p < 0.001). Conclusions: Shorter-course WBRT with 5 Multiplication-Sign 4 Gy was not inferior to 10 Multiplication-Sign 3 Gy with respect to overall survival or local control in elderly patients. 5 Multiplication-Sign 4 Gy appears preferable for the majority of these patients.

  14. Brain Energy Metabolism During Experimental Neonatal Seizures

    E-Print Network [OSTI]

    Wasterlain, Claude G.; Thompson, Kerry W.; Suchomelova, Lucie; Niquet, Jerome

    2010-01-01T23:59:59.000Z

    premature or term neonate, brain ATP concentrations measuredreversible energy loss in the hypoxic immature rat brain.Brain Res Dev Brain Res 73(1):99–105 20. King LJ, Lowry OH,

  15. Prior information for brain parcellation

    E-Print Network [OSTI]

    Pohl, Kilian Maria

    2005-01-01T23:59:59.000Z

    To better understand brain disease, many neuroscientists study anatomical differences between normal and diseased subjects. Frequently, they analyze medical images to locate brain structures influenced by disease. Many of ...

  16. The application of network coding to multicast routing in wireless networks

    E-Print Network [OSTI]

    Jennings, Michael (Michael Vincent)

    2007-01-01T23:59:59.000Z

    This thesis considers the application of network coding and opportunistic routing to improve the performance of multicast flows in wireless networks. Network coding allows routers to randomly mix packets before forwarding ...

  17. How Minds Work Brains, Ontologies &

    E-Print Network [OSTI]

    Memphis, University of

    or software agent is a virtual machine implemented on another virtual machine · The minds of humans or animals are virtual machines implemented on brains #12;Brains, Ontologies & Virtual Machines 13 Virtual1 How Minds Work Brains, Ontologies & Virtual Machines Stan Franklin Computer Science Division

  18. Outcomes After Whole Brain Reirradiation in Patients With Brain Metastases

    SciTech Connect (OSTI)

    Son, Christina H. [School of Medicine, Duke University, Durham, NC (United States); Jimenez, Rachel; Niemierko, Andrzej; Loeffler, Jay S.; Oh, Kevin S. [Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA (United States); Shih, Helen A., E-mail: hshih@partners.org [Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA (United States)

    2012-02-01T23:59:59.000Z

    Purpose: Patients with brain metastases are often treated with whole brain radiation therapy (WBRT) for purposes of palliation. The treatment of those who experience subsequent intracranial disease progression can include a second course of WBRT, although there is controversy surrounding its safety and efficacy. This study examines the outcomes in patients at Massachusetts General Hospital who underwent reirradiation. Patients and Methods: We examined the medical records of 17 patients at Massachusetts General Hospital with brain metastases who were initially treated with WBRT between 2002 and 2008 and were subsequently retreated with a second course of WBRT. The median dose for the first course of WBRT was 35 Gy (range, 28-40 Gy), with a fraction size of 2 to 3 Gy (median, 2.5 Gy). The median dose at reirradiation was 21.6 Gy (range, 14-30 Gy), with a fraction size of 1.5 to 2 Gy (median, 1.8 Gy). Results: The second course of WBRT was administered upon radiographic disease progression in all patients. Of 10 patients with complete follow-up data, 8 patients experienced complete or partial symptom resolution, and 2 did not show clinical improvement. The time to radiographic progression was 5.2 months. The median overall survival for all patients after diagnosis of metastases was 24.7 months. The median survival time after initiation of reirradiation was 5.2 months (95% CI, 1.3-8.7). In 6 patients with stable extracranial disease, the median survival time after retreatment was 19.8 months (95% CI, 2.7-{infinity}), compared with 2.5 months (95% CI, 0.8-5.5) for those with extracranial disease progression (p = 0.05). Acute adverse reactions occurred in 70.5% of patients but were mild to moderate in severity. Conclusion: In select patients and especially those with stable extracranial disease, reirradiation may be an appropriate and effective intervention to provide symptomatic relief and slow intracranial disease progression. Side effects were minimal and did not cause substantial changes in quality of life.

  19. 196 IEEE TRANSACTIONS ON NEURAL NETWORKS, VOL. 10, NO. 1, JANUARY 1999 mance improves substantially as the degree of overlap is increased

    E-Print Network [OSTI]

    Chow, Mo-Yuen

    and a consistent trend in performance variations with the degree of training and testing sample overlap. IV" Training Algorithm for Fuzzy Adaptive Logic Control/Decision Network (FALCON) Sinan Altug, H. Joel Trussell using the Armijo rule. In our motor fault detection study case, the mutual update algorithm arrived

  20. anatomical lymphatic mapping: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    differ between Aitken, Stuart 3 A simple way to improve anatomical mapping of functional brain imaging Nicolas Villain, MSc1 Physics Websites Summary: , Caen, France Running head:...

  1. Quantitative Brain Electrical Activity in the Initial Screening of Mild Traumatic Brain Injuries

    E-Print Network [OSTI]

    O'Neil, Brian; Prichep, Leslie S.; Naunheim, Roseanne; Chabot, Robert

    2012-01-01T23:59:59.000Z

    investigation into mild brain injury and discriminantfrequency bands (32-64 Hz). Brain Inj. 24. Thakor NV, Tongfor accuracy traumatic brain injury. J Neuropsychiatry Clin

  2. Capability Improvement

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Trinity NERSC-8 Capability Improvement Trinity NERSC-8 Capability Improvement As stated in Section 3.5 of the Technical Requirements, The performance of the ASC and NERSC...

  3. Does Brain-Training Make You Smarter? Evidence from Working Memory Training Studies

    E-Print Network [OSTI]

    Rose, Michael R.

    Does Brain-Training Make You Smarter? Evidence from Working Memory Training Studies Guest Lecture by Claudia von Bastian Psychology & Neuroscience be improved through cognitive training? This question is still highly controversial

  4. Transcranial LED therapy for cognitive dysfunction in chronic, mild traumatic brain injury: Two case reports

    E-Print Network [OSTI]

    Hamblin, Michael R.

    Two chronic, traumatic brain injury (TBI) cases are presented, where cognitive function improved following treatment with transcranial light emitting diodes (LEDs). At age 59, P1 had closed-head injury from a motor vehicle ...

  5. EFFECTS OF EXERCISE TRAINING ON BRAIN BIOENERGETICS: LACTATE AS A KEY MEDIATOR

    E-Print Network [OSTI]

    E, Lezi

    2013-12-31T23:59:59.000Z

    Exercise has been given credits for promoting health in general. Research show various exercise-induced benefits for brain in both humans and rodents, including improvement of cognitive function, increase of adult neurogenesis, ...

  6. Automatic Seedpoint Selection and Tracing of Microstructures in the Knife-Edge Scanning Microscope Mouse Brain Data Set

    E-Print Network [OSTI]

    Kim, Dongkun

    2011-10-21T23:59:59.000Z

    in neuronal structures [4]. Research about the neuronal structure can also help understand how the neuronal structure processes information. In order to investigate neuronal structures, researchers at the Brain Network Lab (BNL) at Texas A&M University... by re- searchers at the Brain Network Laboratory (BNL) at Texas A&M University (TAMU) to scan entire mouse brains at a sub-micrometer resolution (down to 300 nm). This instrument consists of a high-precision stage, a diamond knife and an illuminator...

  7. Quantum features of consciousness, computers and brain

    E-Print Network [OSTI]

    Michael B. Mensky

    2009-10-22T23:59:59.000Z

    Many people believe that mysterious phenomenon of consciousness may be connected with quantum features of our world. The present author proposed so-called Extended Everett's Concept (EEC) that allowed to explain consciousness and super-consciousness (intuitive knowledge). Brain, according to EEC, is an interface between consciousness and super-consciousness on the one part and body on the other part. Relations between all these components of the human cognitive system are analyzed in the framework of EEC. It is concluded that technical devices improving usage of super-consciousness (intuition) may exist.

  8. Interference Effects in the Brain

    E-Print Network [OSTI]

    Jerzy Szwed

    2008-03-14T23:59:59.000Z

    Interference effects are the most spectacular manifestation of the wave nature of phenomena. This note proposes a systematic search for such effects in the brain.

  9. Google matrix analysis of directed networks

    E-Print Network [OSTI]

    Leonardo Ermann; Klaus M. Frahm; Dima L. Shepelyansky

    2014-09-01T23:59:59.000Z

    In past ten years, modern societies developed enormous communication and social networks. Their classification and information retrieval processing become a formidable task for the society. Due to the rapid growth of World Wide Web, social and communication networks, new mathematical methods have been invented to characterize the properties of these networks on a more detailed and precise level. Various search engines are essentially using such methods. It is highly important to develop new tools to classify and rank enormous amount of network information in a way adapted to internal network structures and characteristics. This review describes the Google matrix analysis of directed complex networks demonstrating its efficiency on various examples including World Wide Web, Wikipedia, software architecture, world trade, social and citation networks, brain neural networks, DNA sequences and Ulam networks. The analytical and numerical matrix methods used in this analysis originate from the fields of Markov chains, quantum chaos and Random Matrix theory.

  10. Google matrix analysis of directed networks

    E-Print Network [OSTI]

    Leonardo Ermann; Klaus M. Frahm; Dima L. Shepelyansky

    2015-06-19T23:59:59.000Z

    In past ten years, modern societies developed enormous communication and social networks. Their classification and information retrieval processing become a formidable task for the society. Due to the rapid growth of World Wide Web, social and communication networks, new mathematical methods have been invented to characterize the properties of these networks on a more detailed and precise level. Various search engines are essentially using such methods. It is highly important to develop new tools to classify and rank enormous amount of network information in a way adapted to internal network structures and characteristics. This review describes the Google matrix analysis of directed complex networks demonstrating its efficiency on various examples including World Wide Web, Wikipedia, software architecture, world trade, social and citation networks, brain neural networks, DNA sequences and Ulam networks. The analytical and numerical matrix methods used in this analysis originate from the fields of Markov chains, quantum chaos and Random Matrix theory.

  11. An introduction to artificial neural networks

    E-Print Network [OSTI]

    C. A. L. Bailer-Jones; R. Gupta; H. P. Singh

    2001-02-13T23:59:59.000Z

    Artificial neural networks are algorithms which have been developed to tackle a range of computational problems. These range from modelling brain function to making predictions of time-dependent phenomena to solving hard (NP-complete) problems. In this introduction we describe a single, yet very important, type of network known as a feedforward network. This network is a mathematical model which can be trained to learn an arbitrarily complex relationship between a data and a parameter domain, so can be used to solve interpolation and classification problems. We discuss the structure, training and interpretation of these networks, and their implementation, taking the classification of stellar spectra as an example.

  12. Brain MRI Classification using the Expectation Maximization

    E-Print Network [OSTI]

    Chen, Tsuhan

    Brain MRI Classification using the Expectation Maximization made a brain magnetic resonance image (MRI) classification algorithm that uses a twostage applied to a set of normal brain MR images for further testing. We accomplished a working

  13. Vascular pathology in the aged human brain

    E-Print Network [OSTI]

    Grinberg, Lea Tenenholz; Thal, Dietmar Rudolf

    2010-01-01T23:59:59.000Z

    vascular pathology, and the AD brain. Neurology 65: 259–265brospinal ?uid from the rat brain. Acta Neuropathol (Berl)and Alzheimer’s disease in the brains of elderly individuals

  14. azidothymidine azt treatment: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    were investigated using murine and (more) Lee, Sung-Hack 2008-01-01 6 Classification of brain compartments and head injury lesions by neural networks applied to magnetic...

  15. Network Chimera Network Chimera

    E-Print Network [OSTI]

    Network Chimera Network Chimera Objective Chimera aims to understand how the network properties enough with limited resources. The Chimera team is cross-disciplinary, and includes computer scientists Impact The original hypothesis of Chimera was that a physical network could be reduced to a graph

  16. Social Networking? Secure Networking?

    E-Print Network [OSTI]

    Chapman, Michael S.

    Social Networking? Secure Networking? Teaching & Learning Technology Roundtable February 2010 #12 ­ The intent behind the current security measures in place at OHSU ­ The OHSU Social Networking Guidelines 2. To begin a campus wide dialogue exploring the changing world of online social networking and it

  17. Rapid brain scanning radiopharmaceutical

    DOE Patents [OSTI]

    Sargent, T.W. III; Shulgin, A.T.; Mathis, C.A.

    1987-03-03T23:59:59.000Z

    A method for detecting the blood flow in animals, particularly in the brain, is provided wherein a detectable amount of a novel radioactive compound of the formula 1 is administered to one animal: as given in figure in patent wherein R[sub 1] and R[sub 2] are independently alkyl of 1 to 6 carbon atoms or benzyl; R[sub 3] is alkyl of 1 to 6 carbon atoms, benzyl, cyclopropylalkyl of 4 to 6 carbon atoms, or cyanoalkyl of 2 to 6 carbon atoms; R[sub 4] is hydrogen, benzyl or alkyl of 1 to 6 carbon atoms; with the provisos that R[sub 4] is not isopropyl and when R[sub 4] is methyl, R[sub 3] is not benzyl; and X is a radioactive halogen. 2 figs.

  18. Rapid brain scanning radiopharmaceutical

    DOE Patents [OSTI]

    Sargent, III, Thornton W. (Berkeley, CA); Shulgin, Alexander T. (Lafayette, CA); Mathis, Chester A. (Oakland, CA)

    1987-01-01T23:59:59.000Z

    A method for detecting the blood flow in animals, particularly in the brain, is provided wherein a detectable amount of a novel radioactive compound of the formula I is administered to one animal: ##STR1## wherein R.sub.1 and R.sub.2 are independently alkyl of 1 to 6 carbon atoms or benzyl; R.sub.3 is alkyl of 1 to 6 carbon atoms, benzyl, cyclopropylalkyl of 4 to 6 carbon atoms, or cyanoalkyl of 2 to 6 carbon atoms; R.sub.4 is hydrogen, benzyl or alkyl of 1 to 6 carbon atoms; with the provisos that R.sub.4 is not isopropyl and when R.sub.4 is methyl, R.sub.3 is not benzyl; and X is a radioactive halogen.

  19. Clock synchronization for mobile ad hoc networks 

    E-Print Network [OSTI]

    Chandra, Rajan

    2013-02-22T23:59:59.000Z

    As mobile networking advances, there is a need for services such as clock synchronization that improve performance and support the development of higher-level applications. This can be achieved by adapting existing algorithms (such as the Network...

  20. SU-E-T-51: Bayesian Network Models for Radiotherapy Error Detection

    SciTech Connect (OSTI)

    Kalet, A; Phillips, M; Gennari, J [UniversityWashington, Seattle, WA (United States)

    2014-06-01T23:59:59.000Z

    Purpose: To develop a probabilistic model of radiotherapy plans using Bayesian networks that will detect potential errors in radiation delivery. Methods: Semi-structured interviews with medical physicists and other domain experts were employed to generate a set of layered nodes and arcs forming a Bayesian Network (BN) which encapsulates relevant radiotherapy concepts and their associated interdependencies. Concepts in the final network were limited to those whose parameters are represented in the institutional database at a level significant enough to develop mathematical distributions. The concept-relation knowledge base was constructed using the Web Ontology Language (OWL) and translated into Hugin Expert Bayes Network files via the the RHugin package in the R statistical programming language. A subset of de-identified data derived from a Mosaiq relational database representing 1937 unique prescription cases was processed and pre-screened for errors and then used by the Hugin implementation of the Estimation-Maximization (EM) algorithm for machine learning all parameter distributions. Individual networks were generated for each of several commonly treated anatomic regions identified by ICD-9 neoplasm categories including lung, brain, lymphoma, and female breast. Results: The resulting Bayesian networks represent a large part of the probabilistic knowledge inherent in treatment planning. By populating the networks entirely with data captured from a clinical oncology information management system over the course of several years of normal practice, we were able to create accurate probability tables with no additional time spent by experts or clinicians. These probabilistic descriptions of the treatment planning allow one to check if a treatment plan is within the normal scope of practice, given some initial set of clinical evidence and thereby detect for potential outliers to be flagged for further investigation. Conclusion: The networks developed here support the use of probabilistic models into clinical chart checking for improved detection of potential errors in RT plans.

  1. BU BRAIN Self Service GRADING PROCEDURES

    E-Print Network [OSTI]

    Suzuki, Masatsugu

    1 BU BRAIN Self Service GRADING PROCEDURES FOR FACULTY Updated May 2014/PD #12;2 Table of Contents BRAIN Self Service icon on left side of page: #12;4 Entering Grades: Once in BU BRAIN Self Service, go BRAIN Self Service; Registered ­ student registered through the department). Grade: Student's grade

  2. Whole-Brain Thinking in Systems Architecting

    E-Print Network [OSTI]

    Udwadia, Firdaus E.

    Whole-Brain Thinking in Systems Architecting Tony Di Carlo,1, * Behrokh Khoshnevis,2 and Firdaus, University of Southern California, Los Angeles, CA 90089 WHOLE-BRAIN THINKING IN SYSTEMS ARCHITECTING paper explores the role of whole-brain thinking in the context of systems architecting. Brain research

  3. 5 Minute Brain Teaser Old vs. New Thinking Regarding the Human Brain

    E-Print Network [OSTI]

    5 Minute Brain Teaser Old vs. New Thinking Regarding the Human Brain Please circle the statement out of each pair that reflects the most current thinking regarding the human brain. # Statement 1. A. How a brain develops depends solely on the genes you are born with. B. Brain development depends

  4. A Brain-to-Brain Interface for Real-Time Sharing of Sensorimotor Information

    E-Print Network [OSTI]

    Indiana University

    A Brain-to-Brain Interface for Real-Time Sharing of Sensorimotor Information Miguel Pais-Vieira1 Safra International Institute for Neuroscience of Natal (ELS-IINN), RN 59066-060, Natal, Brazil. A brain-to-brain the brains of two rats. In this BTBI, an ``encoder'' rat performed sensorimotor tasks that required

  5. Brain imaging methods used in experimental brain research such as Positron Emission Tomography (PET) and Functional

    E-Print Network [OSTI]

    Mueller, Klaus

    ABSTRACT Brain imaging methods used in experimental brain research such as Positron Emission and are best understood in the context of the underlying 3D brain anatomy. In this paper, we present a novel Brain Mapping, Functional Imaging 1 INTRODUCTION Although the human brain is no longer the black box

  6. Cross-linked structure of network evolution

    SciTech Connect (OSTI)

    Bassett, Danielle S., E-mail: dsb@seas.upenn.edu [Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104 (United States); Department of Physics, University of California, Santa Barbara, California 93106 (United States); Sage Center for the Study of the Mind, University of California, Santa Barbara, California 93106 (United States); Wymbs, Nicholas F.; Grafton, Scott T. [Department of Psychology and UCSB Brain Imaging Center, University of California, Santa Barbara, California 93106 (United States)] [Department of Psychology and UCSB Brain Imaging Center, University of California, Santa Barbara, California 93106 (United States); Porter, Mason A. [Oxford Centre for Industrial and Applied Mathematics, Mathematical Institute, University of Oxford, Oxford OX2 6GG (United Kingdom) [Oxford Centre for Industrial and Applied Mathematics, Mathematical Institute, University of Oxford, Oxford OX2 6GG (United Kingdom); CABDyN Complexity Centre, University of Oxford, Oxford, OX1 1HP (United Kingdom); Mucha, Peter J. [Carolina Center for Interdisciplinary Applied Mathematics, Department of Mathematics, University of North Carolina, Chapel Hill, North Carolina 27599 (United States) [Carolina Center for Interdisciplinary Applied Mathematics, Department of Mathematics, University of North Carolina, Chapel Hill, North Carolina 27599 (United States); Department of Applied Physical Sciences, University of North Carolina, Chapel Hill, North Carolina 27599 (United States)

    2014-03-15T23:59:59.000Z

    We study the temporal co-variation of network co-evolution via the cross-link structure of networks, for which we take advantage of the formalism of hypergraphs to map cross-link structures back to network nodes. We investigate two sets of temporal network data in detail. In a network of coupled nonlinear oscillators, hyperedges that consist of network edges with temporally co-varying weights uncover the driving co-evolution patterns of edge weight dynamics both within and between oscillator communities. In the human brain, networks that represent temporal changes in brain activity during learning exhibit early co-evolution that then settles down with practice. Subsequent decreases in hyperedge size are consistent with emergence of an autonomous subgraph whose dynamics no longer depends on other parts of the network. Our results on real and synthetic networks give a poignant demonstration of the ability of cross-link structure to uncover unexpected co-evolution attributes in both real and synthetic dynamical systems. This, in turn, illustrates the utility of analyzing cross-links for investigating the structure of temporal networks.

  7. Brain glycogen - vestigial no more

    E-Print Network [OSTI]

    Swanson, RA; Swanson, RA

    2015-01-01T23:59:59.000Z

    between blood supply and energy demand in brain? Perhaps,re- sponses to the energy demands posed by the localized “energy supply to energy demand (Dienel and Cruz 2003). One

  8. Active Learning Agents with Artificial Neural Brains Byoung-Tak Zhang

    E-Print Network [OSTI]

    studies on active learning agents are described. In the first case, the agent is a robot arm whose task agents. Here the agent is a robot arm and its brain is a neural network (Zhang 1993]. The objective is to learn to position the joint angles of the robot arm so that its hand reaches the target object. Instead

  9. Dual-headed SPECT for awake animal brain imaging

    SciTech Connect (OSTI)

    S. Lee, B. Kross, D. Weisenberger, J. McKisson, J.S. Goddard, J.S. Baba, M.S. Smith

    2012-02-01T23:59:59.000Z

    Motion-corrected awake animal imaging is needed for normal-state investigations of models of neurological disease and brain activity. The awake animal brain SPECT/CT system, AwakeSPECT at Johns Hopkins University has in the past used a single gamma camera for imaging. Enhancements have been made by adding a pinhole collimator to the second gamma camera at the opposite side which has been previously equipped parallel hole collimator. Geometry calibration was performed using a custom built quality control phantom containing three Co-57 point sources and applied to the tomographic reconstruction code. Hot-rod phantom scans with Tc-99m were performed to test sensitivity and resolution improvements. The reconstruction results show significant resolution and sensitivity improvements.

  10. Devastating Brain Injuries: Assessment and Management, Part I: Overview of Brain Death

    E-Print Network [OSTI]

    Dixon, Tara D; Malinoski, Darren

    2009-01-01T23:59:59.000Z

    349:667-674. 11. Capron AM. Brain death – well settled yetWijdicks EFM. The diagnosis of brain death. NEJM. 2001; 344:AA. Organ preservation in a brain dead patient: information

  11. How brain images reveal cognition : an ethnographic study of meaning-making in brain mapping practice

    E-Print Network [OSTI]

    Ala?, Morana

    2006-01-01T23:59:59.000Z

    cortical surface’, Human Brain Mapping, Volume 8, pp. 272-attention affects brain activity in Proc.Natl.Acad.Sci, USA,Atlas of the Human Brain, Stuttgart: Thieme. TOOTELL,

  12. Brain Imaging with Positron Emission Tomography: Quantification and Biomedical Applications in Alzheimer's Disease and Brain Tumors

    E-Print Network [OSTI]

    Wardak, Mirwais

    2013-01-01T23:59:59.000Z

    AB, Elson LM. The human brain coloring book. 1st ed. New21. Toga AW, Mazziotta JC. Brain mapping : the systems. SanSR, Phelps ME. Imaging Brain Function with Positron Emission

  13. I-123 HIPDM brain imaging with a rotating gamma camera and slant-hole collimator

    SciTech Connect (OSTI)

    Polak, J.F.; Holman, B.L.; Moretti, J.L.; Eisner, R.L.; Lister-James, J.; English, R.J.

    1984-04-01T23:59:59.000Z

    The performance of a slant-hole collimator was compared with that of a standard straight-bore, low-energy collimator for tomographic imaging of I-123-iodinated amine brain agent. Improved in-slice resolution was due to the greater proximity between collimator and the subjects' heads. It was concluded that high quality tomographic images of the brain can be obtained from rotating cameras equipped with slant-hole collimators.

  14. Developmental Plasticity in Cartesian Genetic Programming Artificial Neural Networks

    E-Print Network [OSTI]

    Fernandez, Thomas

    Developmental Plasticity in Cartesian Genetic Programming Artificial Neural Networks Maryam Mahsal developmental plasticity in Artificial Neural Networks using Carte- sian Genetic Programming. This is inspired by developmental plasticity that exists in the biological brain allowing it to adapt to a changing environment

  15. Microglial and neuronal abnormalities in the autistic brain

    E-Print Network [OSTI]

    Morgan, John T.

    2009-01-01T23:59:59.000Z

    G. , Dager, S. R. , 2002. Brain sructural abnormalities inwith autistic behavior. Brain Behav Immun 7, 97- Sparks, B.G. , Dager, S. R. , 2002. Brain sructural abnormalities in

  16. Parallel multiscale simulations of a brain aneurysm

    SciTech Connect (OSTI)

    Grinberg, Leopold [Division of Applied Mathematics, Brown University, Providence, RI 02912 (United States)] [Division of Applied Mathematics, Brown University, Providence, RI 02912 (United States); Fedosov, Dmitry A. [Institute of Complex Systems and Institute for Advanced Simulation, Forschungszentrum Jülich, Jülich 52425 (Germany)] [Institute of Complex Systems and Institute for Advanced Simulation, Forschungszentrum Jülich, Jülich 52425 (Germany); Karniadakis, George Em, E-mail: george_karniadakis@brown.edu [Division of Applied Mathematics, Brown University, Providence, RI 02912 (United States)

    2013-07-01T23:59:59.000Z

    Cardiovascular pathologies, such as a brain aneurysm, are affected by the global blood circulation as well as by the local microrheology. Hence, developing computational models for such cases requires the coupling of disparate spatial and temporal scales often governed by diverse mathematical descriptions, e.g., by partial differential equations (continuum) and ordinary differential equations for discrete particles (atomistic). However, interfacing atomistic-based with continuum-based domain discretizations is a challenging problem that requires both mathematical and computational advances. We present here a hybrid methodology that enabled us to perform the first multiscale simulations of platelet depositions on the wall of a brain aneurysm. The large scale flow features in the intracranial network are accurately resolved by using the high-order spectral element Navier–Stokes solver N??T?r. The blood rheology inside the aneurysm is modeled using a coarse-grained stochastic molecular dynamics approach (the dissipative particle dynamics method) implemented in the parallel code LAMMPS. The continuum and atomistic domains overlap with interface conditions provided by effective forces computed adaptively to ensure continuity of states across the interface boundary. A two-way interaction is allowed with the time-evolving boundary of the (deposited) platelet clusters tracked by an immersed boundary method. The corresponding heterogeneous solvers (N??T?r and LAMMPS) are linked together by a computational multilevel message passing interface that facilitates modularity and high parallel efficiency. Results of multiscale simulations of clot formation inside the aneurysm in a patient-specific arterial tree are presented. We also discuss the computational challenges involved and present scalability results of our coupled solver on up to 300 K computer processors. Validation of such coupled atomistic-continuum models is a main open issue that has to be addressed in future work.

  17. HPSS Yearly Network Traffic

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    growth in network traffic to storage over the years. Network Traffic Growth Network Distribution 2010 Network Distribution 2010 Network Distribution 2009 Network Distribution...

  18. Overcoming the blood-brain barrier to taxane delivery for brain tumors and neurodegenerative diseases and brain tumors

    E-Print Network [OSTI]

    Rice, Antonie; Michaelis, Mary L.; Georg, Gunda I.; Liu, Yanbin; Turunen, Brandon; Audus, Kenneth L.

    2003-01-01T23:59:59.000Z

    vessels. After the perfusion, the rat was decapitated and the brain removed for sampling of various regions. The brain tissue was digested in Solvable for 24 hrs and the radioactivity quantified via liquid scintillation spectrometry. The capillary...

  19. Construction of the Social Network Score (SNS) Questionnaire for undergraduate students, and an examination of the pre-requisites for large social networks in humans? 

    E-Print Network [OSTI]

    Stileman, Edward

    2007-01-01T23:59:59.000Z

    Dunbar’s Social Brain Hypothesis posits the growth of the neocortex as the basis for larger social networks in primates compared with other species. The theory suggests that the neocortex is critical in the role of manipulating social information...

  20. BrainMap `95 workshop

    SciTech Connect (OSTI)

    NONE

    1995-12-31T23:59:59.000Z

    The fourth annual BrainMap workshop was held at La Mansion del Rio Hotel in San Antonio December 3--4, 1995. The conference title was ``Human Brain Mapping and Modeling.`` The meeting was attended by 137 registered participants and 30 observers from 82 institutions representing 12 countries. The meeting focused on the technical issues associated with brain mapping and modeling. A total of 23 papers were presented covering the following topics: spatial normalization and registration; functional image analysis; metanalysis and modeling; and new horizons in biological databases. The full program with abstracts was available on the Research Imaging Center`s web site. A book will be published by John Wiley and Sons prior to the end of 1998.

  1. A Note on Boltzmann Brains

    E-Print Network [OSTI]

    Yasunori Nomura

    2015-03-02T23:59:59.000Z

    Understanding the observed arrow of time is equivalent, under general assumptions, to explaining why Boltzmann brains do not overwhelm ordinary observers. It is usually thought that this provides a condition on the decay rate of every cosmologically accessible de Sitter vacuum, and that this condition is determined by the production rate of Boltzmann brains calculated using semiclassical theory built on each such vacuum. We argue, based on a recently developed picture of microscopic quantum gravitational degrees of freedom, that this thinking needs to be modified. In particular, depending on the structure of the fundamental theory, the decay rate of a de Sitter vacuum may not have to satisfy any condition except for the one imposed by the Poincare recurrence. The framework discussed here also addresses the question of whether a Minkowski vacuum may produce Boltzmann brains.

  2. area network umts: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    but also helps improve the QoS of the core network and saves the carriers' OPEX and CAPEX on their core networks. Ouyang, Ye; 10.5121ijngn.2010.2105 2010-01-01 17 UMTS-WiMAX...

  3. The Maximum Stable Broadcast Throughput for Wireless Line Networks with Network Coding and

    E-Print Network [OSTI]

    Kuzmanovic, Aleksandar

    Engineering and Computer Science, Northwestern University, Evanston, IL 60208, USA Intelligent Automation Inc cluster size. We show that network coding improves the stable rate over plain retransmissions

  4. Mind, Brain and Education as a Framework for Curricular Reform /

    E-Print Network [OSTI]

    Larrison, Abigail L.

    2013-01-01T23:59:59.000Z

    Eds. ). (2008). The educated brain. Cambridge: CambridgeM. M. & Gentile, D. A. (2011). Brains on video games. NatureA first course in mind, brain, and education. Mind, Brain, &

  5. The effects of alcohol and aspirin on neonatal brain development

    E-Print Network [OSTI]

    Beshear, Myra Dawn

    2013-02-22T23:59:59.000Z

    This study focuses on the effects of alcohol and aspirin on brain development in the neonatal rat. The period of brain development of particular interest is known as the brain growth spurt. Previous studies have shown that the developing brain...

  6. CORTICAL BRAIN SURFACE MAPPING FOR STUDYING PARTIAL VOLUME EFFECTS IN BRAIN FDG PET IMAGES

    E-Print Network [OSTI]

    Thompson, Paul

    CORTICAL BRAIN SURFACE MAPPING FOR STUDYING PARTIAL VOLUME EFFECTS IN BRAIN FDG PET IMAGES Hillary PET images is confounded by tissue atrophy and partial volume effects, especially in patients-based cortical brain surface mapping technique to account for partial volume effects on brain FDG PET images

  7. 5 Minute Brain Teaser Old vs. New Thinking Regarding the Human Brain*

    E-Print Network [OSTI]

    5 Minute Brain Teaser Old vs. New Thinking Regarding the Human Brain* Answer Key Answer Statement 1-B Brain development depends on the interplay between the genes you are born with and the experiences of the effects of genes and experiences on brain development. Is it the genetic make-up (nature) of a human

  8. Words in the brain: lexical determinants of word-induced brain activity

    E-Print Network [OSTI]

    Coulson, Seana

    Words in the brain: lexical determinants of word-induced brain activity Lee Osterhout*, Mark Allen Abstract Many studies have shown that open- and closed-class words elicit different patterns of brain. Introduction Is the brain response to words determined primarily by their linguistic functions

  9. Using Brain Weight to Predict Gestation in Mammals Bivariate Fit of Gestation By Brain Weight

    E-Print Network [OSTI]

    Carriquiry, Alicia

    1 Using Brain Weight to Predict Gestation in Mammals Bivariate Fit of Gestation By Brain Weight 0 100 200 300 400 500 Gestation 0 500 1000 1500 BrainWgt Linear Fit (All 50 mammals) Predicted Gestation = 85.248543 + 0.299867 Brain Weight Summary of Fit RSquare 0.372483 RSquare Adj 0.35941 Root Mean

  10. Brain-shift aware risk map for Deep Brain Stimulation Planning

    E-Print Network [OSTI]

    Boyer, Edmond

    Brain-shift aware risk map for Deep Brain Stimulation Planning Bilger Alexandre 1 , Essert Caroline / Université de Strasbourg, FRANCE Abstract. In Deep Brain Stimulation surgery, the eciency of the pro- cedure of the placement is dicult due to brain shifts occurring during and after the procedure. We propose an approach

  11. Adaptive Brain-Computer Interface Passive brain-computer interfaces are designed to use

    E-Print Network [OSTI]

    Boetticher, Gary D.

    Adaptive Brain-Computer Interface Abstract Passive brain-computer interfaces are designed to use brain activity as an additional input, allowing the adaptation of the interface in real time according to the user's mental state. While most current brain computer interface research (BCI) is designed for direct

  12. Brain imaging methods used in experimental brain research such as Positron Emission Tomography (PET) and Functional

    E-Print Network [OSTI]

    Mueller, Klaus

    ABSTRACT Brain imaging methods used in experimental brain research such as Positron Emission of methods create statistical parametric maps (SPMs) of the brain on a voxel- basis. In our approach, they are best understood in the context of the underly- ing 3-D brain anatomy. However, despite the power

  13. Playing with Your Brain: Brain-Computer Interfaces and Anton Nijholt

    E-Print Network [OSTI]

    Rajamani, Sriram K.

    Playing with Your Brain: Brain-Computer Interfaces and Games Anton Nijholt University of Twente role of brain-computer interaction in computer games and entertainment computing. The assumption is that brain activity, whether it is consciously controlled and directed by the user or just recorded in order

  14. Interspecies Avian Brain Chimeras Reveal That Large Brain Size Differences Are Influenced by Cell

    E-Print Network [OSTI]

    Jarvis, Erich D.

    Interspecies Avian Brain Chimeras Reveal That Large Brain Size Differences Are Influenced by Cell), and harvested the chimeras at later embryonic stages (between 9­12 days of incubation). The donor and host-C, Balaban E, Jarvis ED (2012) Interspecies Avian Brain Chimeras Reveal That Large Brain Size Differences

  15. Guest Editorial: Brain/Neuronal-Computer Game Interfaces and Interaction 1. Brain-Computer Games Interaction

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Guest Editorial: Brain/Neuronal-Computer Game Interfaces and Interaction 1. Brain-Computer Games are controlled through brain-computer interface (BCI) technology which requires sophisticated signal processing is a challenge being addressed by many researchers. Producing paradigms for training users to produce brain

  16. Brain Research and DLM: An overview

    E-Print Network [OSTI]

    Irby, Beverly J.; Lara-Alecio, Rafael

    2010-10-22T23:59:59.000Z

    Brain Research and DLM: An Overview Beverly J. Irby, Ed.D. Professor and Chair Sam Houston State University Rafael Lara-Alecio, Ph.D. Professor and Director Texas A&M University November 4, 2005 Basic Brain Information ? The brain research... us to ?see how mental functions map onto the brain structures? (Bruer, 1997, p. 4). Neuro- science and Education ? There are three well-established findings in developmental neurobiology: ? 1. Starting at infancy and continuing into later...

  17. Improving network routing performance in dynamic environments

    E-Print Network [OSTI]

    Liu, Yong

    2007-04-25T23:59:59.000Z

    for link quality predictability study . . . . . . . . . . . . . 107 79 Example of Internet path quality: average utilization of 40% . . . . . 108 80 Example of Internet path quality: average utilization of 60% . . . . . 109 81 Example of Internet path... quality: average utilization of 80% . . . . . 109 xvii FIGURE Page 82 Internet path quality differences: average utilization of 60% . . . . . 110 83 Autocorrelation functions of link quality metrics: average utiliza- tion of 40...

  18. Improving wireless network performance using sensor hints

    E-Print Network [OSTI]

    Sivalingam, Lenin Ravindranath

    2010-01-01T23:59:59.000Z

    Users of wireless devices often switch between being stationary and in motion while transferring data. Protocols that perform well in the static setting (where the channel conditions are relatively stable), however, tend ...

  19. Improved Electrical Contact For Dowhhole Drilling Networks

    DOE Patents [OSTI]

    Hall, David R. (Provo, UT); Hall, Jr., H. Tracy (Provo, UT); Pixton, David S. (Lehi, UT); Dahlgren, Scott (Provo, UT); Fox, Joe (Spanish Fork, UT); Sneddon, Cameron (Provo, UT)

    2005-08-16T23:59:59.000Z

    An electrical contact system for transmitting information across tool joints while minimizing signal reflections that occur at the tool joints includes a first electrical contact comprising an annular resilient material. An annular conductor is embedded within the annular resilient material and has a surface exposed from the annular resilient material. A second electrical contact is provided that is substantially equal to the first electrical contact. Likewise, the second electrical contact has an annular resilient material and an annular conductor. The two electrical contacts configured to contact one another such that the annular conductors of each come into physical contact. The annular resilient materials of each electrical contact each have dielectric characteristics and dimensions that are adjusted to provide desired impedance to the electrical contacts.

  20. Brain Surface Conformal Parameterization with Algebraic Functions

    E-Print Network [OSTI]

    Wang, Yalin

    Brain Surface Conformal Parameterization with Algebraic Functions Yalin Wang1,2 , Xianfeng Gu3 a brain surface to a multi-hole disk. The re- sulting parameterizations do not have any singularities of anatomical surfaces in MRI scans of the brain, in- cluding the hippocampi and the cerebral cortices

  1. Brain dynamics promotes function Carlos Lourenco

    E-Print Network [OSTI]

    Lisboa, Universidade Técnica de

    Brain dynamics promotes function Carlos Louren¸co 1 Faculty of Sciences of the University of Lisbon, 1049-001 Lisboa - Portugal Abstract. Dynamical structure in the brain promotes biological func- tion. Computational scientists have new opportunities to receive 'algorithmic' inspiration from brain processes

  2. Brain Organization and Computation Andreas Schierwagen

    E-Print Network [OSTI]

    Schierwagen, Andreas

    Brain Organization and Computation Andreas Schierwagen Institute for Computer Science, Intelligent://www.informatik.uni-leipzig.de/~schierwa Abstract. Theories of how the brain computes can be differentiated in three general conceptions systems approach. The discussion of key features of brain organization (i.e. structure with function

  3. Understanding complexity in the human brain

    E-Print Network [OSTI]

    Gazzaniga, Michael

    Understanding complexity in the human brain Danielle S. Bassett1 and Michael S. Gazzaniga2 1 the ultimate aim of neuroscientific enquiry is to gain an understanding of the brain and how its work- ings of mind­brain mechanisms if the cumulative findings from these neu- roscientific studies are coupled

  4. Brain Evolution Relevant to P. Thomas Schoenemann

    E-Print Network [OSTI]

    Schoenemann, P. Thomas

    Brain Evolution Relevant to Language P. Thomas Schoenemann James Madison University 1. Introduction The evolution of language obviously presupposes a brain that made language possible. At the same time, given of the human brain must have been language. Given that language is at least as much a cultural

  5. PUZZLING SYMPTOMS: EATING DISORDERS AND THE BRAIN

    E-Print Network [OSTI]

    Squire, Larry R.

    PUZZLING SYMPTOMS: EATING DISORDERS AND THE BRAIN A FAMILY GUIDE TO THE NEUROBIOLOGY OF EATING TO DO WITH THE BRAIN? Although people with eating disorders struggle to eat normally, this is only now believe that part of the problem has to do with how our brains process information about

  6. Brain Imaging Findings in Neuropathic Pain

    E-Print Network [OSTI]

    Apkarian, A. Vania

    Brain Imaging Findings in Neuropathic Pain Paul Y. Geha, MD and A. Vania Apkarian, PhD* Address (posther- petic neuralgia), then the spinal cord (postspinal cord injury pain), to the brain itself mechanisms; hence, they assume implicitly or explicitly that the rest of the brain passively responds

  7. Bernard J. Baars How Brain Reveals Mind

    E-Print Network [OSTI]

    Memphis, University of

    Bernard J. Baars How Brain Reveals Mind Neural Studies Support the Fundamental Role of Conscious Experience Abstract: In the last decade, careful studies of the living brain have opened the way for human by seven cases: (1) the discovery of widespread brain activation during conscious perception; (2) high

  8. 1. Brain vs Computer Brian Whitworth

    E-Print Network [OSTI]

    Whitworth, Brian

    gates (McCulloch & Pitts, 1943) · The brain has input/output · 1012+ (thousand billion) neurons per head7/12/2011 1 1. Brain vs Computer © Brian Whitworth An Overview http://brianwhitworth.com 2 Aim Compare how computers process information vs how the brain process the senses? Define the main differences

  9. Corps Improvement 

    E-Print Network [OSTI]

    Wythe, Kathy

    2007-01-01T23:59:59.000Z

    in the Upper Trinity River Basin was mainly from findings in a Corps environmental impact statement (EIS) report in the 1980s, according to Gene Rice, Corps project manager of the Dallas Floodway and Dallas Floodway Extension projects, two of the Trinity River... to mitigate environmental impacts of the proj- ect. The Corps? Fort Worth District and the City of Dallas are using an innovative approach to return floodplain value to the Trinity River, while improving flood damage reduction. Big Fossil Creek Watershed...

  10. Artificial Neural Networks Single Layer Networks Multi Layer Networks Generalization Artificial Neural Networks

    E-Print Network [OSTI]

    Kjellström, Hedvig

    Artificial Neural Networks Single Layer Networks Multi Layer Networks Generalization Artificial Neural Networks Artificial Neural Networks Single Layer Networks Multi Layer Networks Generalization 1 Artificial Neural Networks Properties Applications Classical Examples Biological Background 2 Single Layer

  11. Artificial Neural Networks Single Layer Networks Multi Layer Networks Generalization Artificial Neural Networks

    E-Print Network [OSTI]

    Kjellström, Hedvig

    Artificial Neural Networks Single Layer Networks Multi Layer Networks Generalization Artificial Neural Networks #12;Artificial Neural Networks Single Layer Networks Multi Layer Networks Generalization 1 Artificial Neural Networks Properties Applications Classical Examples Biological Background 2

  12. Children's Conceptions of the Brain 

    E-Print Network [OSTI]

    McColl, Judith

    2012-03-14T23:59:59.000Z

    The present study explored children’s developing conceptions of the brain in order to enhance previous research and to contribute to debates regarding the nature of children’s naïve biological theories. 56 participants aged 5, 7 and 9-years-old were...

  13. A COMPARISON OF ARTIFICIAL NEURAL NETWORKS AND CLUSTER ANALYSIS FOR TYPING BIOMETRICS

    E-Print Network [OSTI]

    A COMPARISON OF ARTIFICIAL NEURAL NETWORKS AND CLUSTER ANALYSIS FOR TYPING BIOMETRICS biometrics, artificial neural networks, cluster analysis, Multi Layer Perceptrons, K- means clustering are clustering techniques and Artificial Neural Networks , in conjunction with data processing to improve

  14. Improving the performance of BITNET

    E-Print Network [OSTI]

    Ku, Chih-Hsiung

    1989-01-01T23:59:59.000Z

    diff'erent heuristics have been adopted to design large and distributed computer networks. The cut-saturation heuristic has been shown to be a, very ef- ficient method for topological design. In this thesis, the cut-saturation heunst&c is employed... to improve the performance of BITNET. In addition, a topology con- straint (retention of BITNET connectivitv) is also adopted. The traditionai cut-saturation heuristic as reported in the literature uses a single capacity for simplicity. A combination...

  15. Corps Improvement

    E-Print Network [OSTI]

    Wythe, Kathy

    2007-01-01T23:59:59.000Z

    tx H 2 O | pg. 6 O ne of the key federal players in the restoration of the Trinity River Basin is the U.S. Army Corps of Engineers, whose primary civil mission is developing and managing the nation?s water resources, including projects to reduce... flood damage; improve navigation channels and harbors; protect wetlands; and preserve, safeguard and enhance the environment. The Corps has been involved in the Trinity River Basin for more than 50 years, but the impetus for the current projects...

  16. A versatile clearing agent for multi-modal brain imaging

    E-Print Network [OSTI]

    Costantini, Irene; Di Giovanna, Antonino Paolo; Mascaro, Anna Letizia Allegra; Silvestri, Ludovico; Müllenbroich, Marie Caroline; Onofri, Leonardo; Conti, Valerio; Vanzi, Francesco; Sacconi, Leonardo; Guerrini, Renzo; Markram, Henry; Iannello, Giulio; Pavone, Francesco Saverio

    2015-01-01T23:59:59.000Z

    Extensive mapping of neuronal connections in the central nervous system requires high-throughput um-scale imaging of large volumes. In recent years, different approaches have been developed to overcome the limitations due to tissue light scattering. These methods are generally developed to improve the performance of a specific imaging modality, thus limiting comprehensive neuroanatomical exploration by multimodal optical techniques. Here, we introduce a versatile brain clearing agent (2,2'-thiodiethanol; TDE) suitable for various applications and imaging techniques. TDE is cost-efficient, water-soluble and low-viscous and, more importantly, it preserves fluorescence, is compatible with immunostaining and does not cause deformations at sub-cellular level. We demonstrate the effectiveness of this method in different applications: in fixed samples by imaging a whole mouse hippocampus with serial two-photon tomography; in combination with CLARITY by reconstructing an entire mouse brain with light sheet microscopy...

  17. perfSONAR Workshop Helps Network Engineers Improve Network Performance...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    at ESnet, were the featured speakers at "perfSONAR Deployment Best Practices, Architecture, and Moving the Needle," organized by ESnet and Internet2 and hosted Jan. 21-22 by...

  18. Int. J. Patt. Recog. Art. Intell., Special Issue on MR Brain Image Analysis, 1997 1 An Integrated Approach for Locating Neuroanatomical Structure from MRI1

    E-Print Network [OSTI]

    Duncan, James S.

    Int. J. Patt. Recog. Art. Intell., Special Issue on MR Brain Image Analysis, 1997 1 An Integrated Approach for Locating Neuroanatomical Structure from MRI1 Lawrence H. Staib , Amit Chakrabortyy and James S results on synthetic and MR brain images show a significant improvement is achieved as a consequence

  19. Microsystem process networks

    DOE Patents [OSTI]

    Wegeng, Robert S. (Richland, WA); TeGrotenhuis, Ward E. (Kennewick, WA); Whyatt, Greg A. (West Richland, WA)

    2007-09-18T23:59:59.000Z

    Various aspects and applications of microsystem process networks are described. The design of many types of Microsystems can be improved by ortho-cascading mass, heat, or other unit process operations. Microsystems having energetically efficient microchannel heat exchangers are also described. Detailed descriptions of numerous design features in microcomponent systems are also provided.

  20. Microsystem process networks

    DOE Patents [OSTI]

    Wegeng, Robert S. (Richland, WA); TeGrotenhuis, Ward E. (Kennewick, WA); Whyatt, Greg A. (West Richland, WA)

    2006-10-24T23:59:59.000Z

    Various aspects and applications of microsystem process networks are described. The design of many types of microsystems can be improved by ortho-cascading mass, heat, or other unit process operations. Microsystems having exergetically efficient microchannel heat exchangers are also described. Detailed descriptions of numerous design features in microcomponent systems are also provided.

  1. Microsystem process networks

    DOE Patents [OSTI]

    Wegeng, Robert S [Richland, WA; TeGrotenhuis, Ward E [Kennewick, WA; Whyatt, Greg A [West Richland, WA

    2010-01-26T23:59:59.000Z

    Various aspects and applications or microsystem process networks are described. The design of many types of microsystems can be improved by ortho-cascading mass, heat, or other unit process operations. Microsystems having energetically efficient microchannel heat exchangers are also described. Detailed descriptions of numerous design features in microcomponent systems are also provided.

  2. Macroscopic description for networks of spiking neurons

    E-Print Network [OSTI]

    Ernest Montbrió; Diego Pazó; Alex Roxin

    2015-06-22T23:59:59.000Z

    A major goal of neuroscience, statistical physics and nonlinear dynamics is to understand how brain function arises from the collective dynamics of networks of spiking neurons. This challenge has been chiefly addressed through large-scale numerical simulations. Alternatively, researchers have formulated mean-field theories to gain insight into macroscopic states of large neuronal networks in terms of the collective firing activity of the neurons, or the firing rate. However, these theories have not succeeded in establishing an exact correspondence between the firing rate of the network and the underlying microscopic state of the spiking neurons. This has largely constrained the range of applicability of such macroscopic descriptions, particularly when trying to describe neuronal synchronization. Here we provide the derivation of a set of exact macroscopic equations for a network of spiking neurons. Our results reveal that the spike generation mechanism of individual neurons introduces an effective coupling between two biophysically relevant macroscopic quantities, the firing rate and the mean membrane potential, which together govern the evolution of the neuronal network. The resulting equations exactly describe all possible macroscopic dynamical states of the network, including states of synchronous spiking activity. Finally we show that the firing rate description is related, via a conformal map, with a low-dimensional description in terms of the Kuramoto order parameter, called Ott-Antonsen theory. We anticipate our results will be an important tool in investigating how large networks of spiking neurons self-organize in time to process and encode information in the brain.

  3. aml1 core site: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    but also helps improve the QoS of the core network and saves the carriers' OPEX and CAPEX on their core networks. Ouyang, Ye; 10.5121ijngn.2010.2105 2010-01-01 6...

  4. application site performance: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    but also helps improve the QoS of the core network and saves the carriers' OPEX and CAPEX on their core networks. Ouyang, Ye; 10.5121ijngn.2010.2105 2010-01-01 79 Predictive...

  5. arabidopsis core cell: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    but also helps improve the QoS of the core network and saves the carriers' OPEX and CAPEX on their core networks. Ouyang, Ye; 10.5121ijngn.2010.2105 2010-01-01 53 Systematic...

  6. Improved aethalometer

    DOE Patents [OSTI]

    Hansen, A.D.

    1988-01-25T23:59:59.000Z

    An improved aethalometer having a single light source and a single light detector and two light paths from the light source to the light detector. A quartz fiber filter is inserted in the device, the filter having a collection area in one light path and a reference area in the other light path. A gas flow path through the aethalometer housing allows ambient air to flow through the collection area of the filter so that aerosol particles can be collected on the filter. A rotating disk with an opening therethrough allows light for the light source to pass alternately through the two light paths. The voltage output of the detector is applied to a VCO and the VCO pulses for light transmission separately through the two light paths, are counted and compared to determine the absorption coefficient of the collected aerosol particles. 5 figs.

  7. Synchrotron radiation imaging is a powerful tool to image brain microvasculature

    SciTech Connect (OSTI)

    Zhang, Mengqi; Sun, Danni; Xie, Yuanyuan; Xia, Jian; Long, Hongyu; Hu, Kai; Xiao, Bo, E-mail: csuxiaobo123456@163.com [Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan 410008 (China)] [Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan 410008 (China); Peng, Guanyun [Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800 (China)] [Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800 (China)

    2014-03-15T23:59:59.000Z

    Synchrotron radiation (SR) imaging is a powerful experimental tool for micrometer-scale imaging of microcirculation in vivo. This review discusses recent methodological advances and findings from morphological investigations of cerebral vascular networks during several neurovascular pathologies. In particular, it describes recent developments in SR microangiography for real-time assessment of the brain microvasculature under various pathological conditions in small animal models. It also covers studies that employed SR-based phase-contrast imaging to acquire 3D brain images and provide detailed maps of brain vasculature. In addition, a brief introduction of SR technology and current limitations of SR sources are described in this review. In the near future, SR imaging could transform into a common and informative imaging modality to resolve subtle details of cerebrovascular function.

  8. Reorganization of functionally connected brain subnetworks in high-functioning autism

    E-Print Network [OSTI]

    Glerean, Enrico; Salmi, Juha; Kujala, Rainer; Lahnakoski, Juha; Roine, Ulrika; Nummenmaa, Lauri; Leppämäki, Sami; Wendt, Taina Nieminen-von; Tani, Pekka; Saramäki, Jari; Sams, Mikko; Jääskeläinen, Iiro P

    2015-01-01T23:59:59.000Z

    Background: Previous functional connectivity studies have found both hypo- and hyper-connectivity in brains of individuals having autism spectrum disorder (ASD). Here we studied abnormalities in functional brain subnetworks in high-functioning individuals with ASD during free viewing of a movie containing social cues and interactions. Methods: Thirteen subjects with ASD and 13 matched-pair controls watched a 68 minutes movie during functional magnetic resonance imaging. For each subject, we computed Pearson`s correlation between haemodynamic time-courses of each pair of 6-mm isotropic voxels. From the whole-brain functional networks, we derived individual and group-level subnetworks using graph theory. Scaled inclusivity was then calculated between all subject pairs to estimate intersubject similarity of connectivity structure of each subnetwork. Additional 27 individuals with ASD from the ABIDE resting-state database were included to test the reproducibility of the results. Results: Between-group differences...

  9. Network Economics Anna Nagurney

    E-Print Network [OSTI]

    Nagurney, Anna

    Performance/Efficiency Measure with Applications to a Variety of Network Systems · Transportation Network with transportation as the unifying application. #12;Subway Network Railroad Network Iridium Satellite Constellation Network Satellite and Undersea Cable Networks Duke Energy Gas Pipeline Network Transportation

  10. Diffuse optical imaging of brain activation: approaches to optimizing image sensitivity, resolution, and accuracy

    E-Print Network [OSTI]

    Boas, David

    Diffuse optical imaging of brain activation: approaches to optimizing image sensitivity, resolution States Available online 11 September 2004 Near-infrared spectroscopy (NIRS) and diffuse optical imaging currently being made and issues to consider for improving optical image quality. These include the optimal

  11. A Critical Review of the Effect of De-noising Algorithms on MRI Brain Tumor Segmentation

    E-Print Network [OSTI]

    Alberta, University of

    ) in terms of their efficiency, statistical assumptions, and their ability to improve brain tumor, but a more complex Rician distribution [5]. It is well known that almost all image processing filters. Diaz is at Dept. of Comput. Science, U. of Alberta, Canada and U. del Magdalena, Colombia, idanis

  12. Biophysically Accurate Brain Modeling and Simulation using Hybrid MPI/OpenMP Parallel Processing 

    E-Print Network [OSTI]

    Hu, Jingzhen

    2012-07-16T23:59:59.000Z

    simulator using biophysically realistic neural models for the simulation of large scale neural networks. In order to improve the performance of the simulator, we adopt several techniques such as merging linear synaptic receptors mathematically and using two...

  13. adult mammalian brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    bats) correlate with predictable chromosomal structural changes (KFTkaryotypic fission theory). Chromosome studies (more) Kolnicki, Robin Lee 2012-01-01 338 Reading...

  14. adult rodent brains: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Moldestad, J.F. Storm, T.B. Leergaard and J.G. Bjaalie CMBN & IMB, University of Oslo, Norway INTRODUCTION Conventional atlases contain for 3-D reconstruction of series of such...

  15. adult brain tumours: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and sup 1 sup 5 sup 3 Sm-labelled as potential radioimmunotherapy (RIT) radiopharmaceuticals. A variety of malignant tumours over-express somatostatin receptors, proteins...

  16. astrocytic brain tumours: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and sup 1 sup 5 sup 3 Sm-labelled as potential radioimmunotherapy (RIT) radiopharmaceuticals. A variety of malignant tumours over-express somatostatin receptors, proteins...

  17. amine oxime brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    solvent extractants of the types used in the hydrometallurgical recovery of ... Roach, Benjamin David 2011-06-27 5 Synthesis and Cytotoxicity of Silicon and Germanium...

  18. acquired developmental brain: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and speech programming deficit Paris-Sud XI, Universit de 142 Acquired Dyslexia in Japanese: Implications for Reading Theory . Open Access Theses and Dissertations...

  19. attenuates brain edema: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    phenolic structures and are elevated in vegetables, fruits, grains, bark, roots, tea, and wine. There are over 8000 polyphenolic structures identified in plants, but edible plants...

  20. Brain Mapping Using Topology Graphs Obtained by Surface Segmentation

    E-Print Network [OSTI]

    Linsen, Lars

    Brain Mapping Using Topology Graphs Obtained by Surface Segmentation Fabien Vivodtzev1 , Lars@ucdavis.edu Summary. Brain mapping is a technique used to alleviate the tedious and time- consuming process of annotating brains by mapping existing annotations from brain atlases to individual brains. We introduce

  1. BEaST: Brain extraction using multiresolution nonlocal segmentation

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    BEaST: Brain extraction using multiresolution nonlocal segmentation Simon F. Eskildsen1 Østergaard2 , D. Louis Collins1 , and the Alzheimer's Disease Neuroimaging Initiative 1 McConnell Brain. Brain extraction is an important step in the analysis of brain images. Variability in brain morphology

  2. Center for BrainHealtH Scientific exploration at

    E-Print Network [OSTI]

    O'Toole, Alice J.

    Center for BrainHealtH #12;#12;Scientific exploration at BrainHealth is leading edge, innovative and transformative. leading tHe way in tHiS century'S greateSt ScientiFic cauSe The Center for Brain significant cause of the century: To understand, protect and heal the brain. Scientific exploration at Brain

  3. Genotype and ancestry modulate brain's DAT availability in healthy humans

    SciTech Connect (OSTI)

    Shumay, E.; Shumay, E.; Chen, J.; Fowler, J.S.; Volkow, N.D.

    2011-08-01T23:59:59.000Z

    The dopamine transporter (DAT) is a principal regulator of dopaminergic neurotransmission and its gene (the SLC6A3) is a strong biological candidate gene for various behavioral- and neurological disorders. Intense investigation of the link between the SLC6A3 polymorphisms and behavioral phenotypes yielded inconsistent and even contradictory results. Reliance on objective brain phenotype measures, for example, those afforded by brain imaging, might critically improve detection of DAT genotype-phenotype association. Here, we tested the relationship between the DAT brain availability and the SLC6A3 genotypes using an aggregate sample of 95 healthy participants of several imaging studies. These studies employed positron emission tomography (PET) with [{sup 11}C] cocaine wherein the DAT availability was estimated as Bmax/Kd; while the genotype values were obtained on two repeat polymorphisms - 3-UTR- and intron 8- VNTRs. The main findings are the following: (1) both polymorphisms analyzed as single genetic markers and in combination (haplotype) modulate DAT density in midbrain; (2) ethnic background and age influence the strength of these associations; and (3) age-related changes in DAT availability differ in the 3-UTR and intron8 - genotype groups.

  4. Brain Receptor Structures Key to Future Therapeutics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Brain Receptor Structures Key to Future Therapeutics Print With an aging population in America, it is more important than ever to discover ways to treat or prevent diseases...

  5. area prediction method: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of neural networks achieved Vucetic, Slobodan 16 Improved permeability prediction using multivariate analysis methods Texas A&M University - TxSpace Summary: . In statistics,...

  6. atrium comparing architectural: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    on two key technological pillars resource consumption, improved reliability and lower latency, compared to current metro network Lpez, V-ctor 129 Design of 64 bit...

  7. Better Buildings Network View | September 2014 | Department of...

    Broader source: Energy.gov (indexed) [DOE]

    Financing Program: On-Bill Financing Brings Lenders and Homeowners On Board Better Buildings Network View | December 2014 On-Bill Financing for Energy Efficiency Improvements...

  8. Reinforcement Learning in the brain Reading: Y Niv, Reinforcement learning in the brain, 2009.

    E-Print Network [OSTI]

    Seriès, Peggy

    basic types of animal conditioning animal learning) ow do these relate to RL? 20 Monday, 8 March 2010Reinforcement Learning in the brain · Reading: Y Niv, Reinforcement learning in the brain, 2009. wo Reinforcement learning and the brain: the problems we face all day · Decision making at all levels

  9. r Human Brain Mapping 000:000000 (2009) r Brain Structure and Obesity

    E-Print Network [OSTI]

    Thompson, Paul

    2009-01-01T23:59:59.000Z

    r Human Brain Mapping 000:000­000 (2009) r Brain Structure and Obesity Cyrus A. Raji,1,2y April J, School of Medicine, Pittsburgh, Pennsylvania r r Abstract: Obesity is associated with increased risk obesity and Type II diabetes, are associ- ated with specific patterns of brain atrophy. We used tensor

  10. Return of the Boltzmann brains

    SciTech Connect (OSTI)

    Page, Don N. [Institute for Theoretical Physics, Department of Physics, University of Alberta, Room 238 CEB, 11322-89 Avenue, Edmonton, Alberta, CT6G 2G7 (Canada)

    2008-09-15T23:59:59.000Z

    Linde in J. Cosmol. Astropart. Phys. 01 (2007) 022 shows that some (though not all) versions of the global (volume-weighted) description avoid the 'Boltzmann brain' problem raised by Page [Phys. Rev. D 78, 063535 (2008)] if the universe does not have a decay time less than 20 Gyr. Here I give an apparently natural version of the volume-weighted description in which the problem persists, highlighting the ambiguity of taking the ratios of infinite volumes that appear to arise from eternal inflation.

  11. Broadband Collaboration Equipment Mobile Networks Security Storage White Papers Webcasts Tests News Blogs Newsletters Videos Events Resources More

    E-Print Network [OSTI]

    Chiao, Jung-Chih

    Broadband Collaboration Equipment Mobile Networks Security Storage White Papers Webcasts Tests News is absolutely gorgeous View more Latest News Home Networking White Papers Improving Business Value of WAN, improve... Accelerating Cloud Performance with WAN Optimization Today's smart CIOs are assessing

  12. Ultrasound-Enhanced Drug Transport and Distribution in the Brain

    E-Print Network [OSTI]

    2010-01-01T23:59:59.000Z

    enhanced taxol delivery in brain tumor patients usingopening of the blood–brain barrier in rabbits. Radiology.and Distribution in the Brain Ying Liu, 1 Sumit Paliwal, 2

  13. Genetic associations with brain cortical thickness in multiple sclerosis

    E-Print Network [OSTI]

    2015-01-01T23:59:59.000Z

    onset of multiple sclerosis. Brain 131, 808–817. Georgala,in multiple sclerosis. Brain 126, Shannon, P. , Markiel,Genes, Brain and Behavior (2015) 14: 217–227 doi:

  14. Wakate-Initiative Seminar Memory formation in the fly brain!

    E-Print Network [OSTI]

    Ejiri, Shinji

    Wakate-Initiative Seminar Memory formation in the fly brain! Dr. Hiromu Tanimoto Head is synthesized in ~280 neurons in the fly brain and involved also in other brain functions, it is important

  15. Local drug delivery for treatment of brain tumor associated edema

    E-Print Network [OSTI]

    Ong, Qunya

    2014-01-01T23:59:59.000Z

    Brain tumor associated edema, a common feature of malignant brain neoplasms, is a significant cause of morbidity from brain tumor. Systemic administration of corticosteroids, the standard of care, is highly effective but ...

  16. Intraoperative Brain Tumor Resection Cavity Characterization with Conoscopic Holography

    E-Print Network [OSTI]

    Webster III, Robert James

    Intraoperative Brain Tumor Resection Cavity Characterization with Conoscopic Holography Amber L ABSTRACT Brain shift compromises the accuracy of neurosurgical image-guided interventions if not corrected approach to correcting for brain shift. Laser range scan, instrument swabbing, and conoscopic holography

  17. A Hybrid Brain-computer Interface for Intelligent Prosthetics

    E-Print Network [OSTI]

    Cheng, Yu-Che

    2014-12-09T23:59:59.000Z

    Over the past few decades, many researcher have shown that human can use brain signals to communicate with computers or machines by using brain-computer interfaces (BCIs). BCI systems can measure the brain activity and translate them into control...

  18. Modeling the Dynamics of Compromised Networks

    SciTech Connect (OSTI)

    Soper, B; Merl, D M

    2011-09-12T23:59:59.000Z

    Accurate predictive models of compromised networks would contribute greatly to improving the effectiveness and efficiency of the detection and control of network attacks. Compartmental epidemiological models have been applied to modeling attack vectors such as viruses and worms. We extend the application of these models to capture a wider class of dynamics applicable to cyber security. By making basic assumptions regarding network topology we use multi-group epidemiological models and reaction rate kinetics to model the stochastic evolution of a compromised network. The Gillespie Algorithm is used to run simulations under a worst case scenario in which the intruder follows the basic connection rates of network traffic as a method of obfuscation.

  19. ay 1 Mysteries of Brain : Come and `learn about the brain'. Have you wondered, "What is our brain like?" "How do we sense things around us?" and "How do we react to our environment?"

    E-Print Network [OSTI]

    Narayanan, H.

    of Brain : Come and `learn about the brain'. Have you wondered, "What is our brain like?" "How do we sense about `neuron' as a basic unit of the brain, structure of the brain, functions closely associated with brain lobes and hemispheres and understanding the nervous system Special Focus: Brain Hemispheres

  20. Controlling the Internet to Improve Energy Efficiency Dr. Lachlan Andrew

    E-Print Network [OSTI]

    Huang, Jianwei

    Controlling the Internet to Improve Energy Efficiency by Dr. Lachlan Andrew Centre for Advanced, and energy-efficient networking. He is an editor of IEEE/ACM Trans. Networking, and an area editor Internet Architectures Swinburne University of Technology Australia THE CHINESE UNIVERSITY OF HONG KONG

  1. Improving School Governance | 1 Improving School Governance

    E-Print Network [OSTI]

    Rambaut, Andrew

    Improving School Governance | 1 Improving School Governance A Recommended Code of Governance for Schools: A flexible framework for strategic planning October 2012 Pilot version 1 #12;Improving School Governance | 2 #12;Improving School Governance | 3 This pilot version of the Recommended Code of Governance

  2. Efficient network camouflaging in wireless networks 

    E-Print Network [OSTI]

    Jiang, Shu

    2006-04-12T23:59:59.000Z

    when protected networks are wireless networks, such as sensor networks and mobile ad hoc networks. The reason is that wireless networks are typically subject to resource constraints (e.g. bandwidth, power supply) and possess some unique characteristics...

  3. Network Bandwidth Utilization Forecast Model on High Bandwidth Network

    SciTech Connect (OSTI)

    Yoo, Wucherl; Sim, Alex

    2014-07-07T23:59:59.000Z

    With the increasing number of geographically distributed scientific collaborations and the scale of the data size growth, it has become more challenging for users to achieve the best possible network performance on a shared network. We have developed a forecast model to predict expected bandwidth utilization for high-bandwidth wide area network. The forecast model can improve the efficiency of resource utilization and scheduling data movements on high-bandwidth network to accommodate ever increasing data volume for large-scale scientific data applications. Univariate model is developed with STL and ARIMA on SNMP path utilization data. Compared with traditional approach such as Box-Jenkins methodology, our forecast model reduces computation time by 83.2percent. It also shows resilience against abrupt network usage change. The accuracy of the forecast model is within the standard deviation of the monitored measurements.

  4. From blood to the brain: can systemically transplanted mesenchymal stem cells cross the blood-brain barrier?

    E-Print Network [OSTI]

    Liu, Linan; Eckert, Mark A; Riazifar, Hamidreza; Kang, Dong-Ku; Agalliu, Dritan; Zhao, Weian

    2013-01-01T23:59:59.000Z

    and function of the blood-brain barrier,” Neurobiology ofV. Zlokovic, “The blood-brain barrier in health and chroniccell biology of the blood- brain barrier,” Annual Review of

  5. Mapping protein abundance patterns in the brain using voxelation...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    protein abundance patterns in the brain using voxelation combined with liquid chromatography and mass spectrometry. Mapping protein abundance patterns in the brain using voxelation...

  6. Characterization of the Mouse Brain Proteome Using Global Proteomic...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Brain Proteome Using Global Proteomic Analysis Complemented with Cysteinyl-Peptide Enrichment. Characterization of the Mouse Brain Proteome Using Global Proteomic Analysis...

  7. Phoebus: Network Middleware for Next-Generation Network Computing

    SciTech Connect (OSTI)

    Martin Swany

    2012-06-16T23:59:59.000Z

    The Phoebus project investigated algorithms, protocols, and middleware infrastructure to improve end-to-end performance in high speed, dynamic networks. The Phoebus system essentially serves as an adaptation point for networks with disparate capabilities or provisioning. This adaptation can take a variety of forms including acting as a provisioning agent across multiple signaling domains, providing transport protocol adaptation points, and mapping between distributed resource reservation paradigms and the optical network control plane. We have successfully developed the system and demonstrated benefits. The Phoebus system was deployed in Internet2 and in ESnet, as well as in GEANT2, RNP in Brazil and over international links to Korea and Japan. Phoebus is a system that implements a new protocol and associated forwarding infrastructure for improving throughput in high-speed dynamic networks. It was developed to serve the needs of large DOE applications on high-performance networks. The idea underlying the Phoebus model is to embed Phoebus Gateways (PGs) in the network as on-ramps to dynamic circuit networks. The gateways act as protocol translators that allow legacy applications to use dedicated paths with high performance.

  8. Mitigation of Malicious Attacks on Networks

    E-Print Network [OSTI]

    Schneider, Christian M; Andrade, Jose S; Havlin, Shlomo; Herrmann, Hans J; 10.1073/pnas.1009440108

    2011-01-01T23:59:59.000Z

    Terrorist attacks on transportation networks have traumatized modern societies. With a single blast, it has become possible to paralyze airline traffic, electric power supply, ground transportation or Internet communication. How and at which cost can one restructure the network such that it will become more robust against a malicious attack? We introduce a unique measure for robustness and use it to devise a method to mitigate economically and efficiently this risk. We demonstrate its efficiency on the European electricity system and on the Internet as well as on complex networks models. We show that with small changes in the network structure (low cost) the robustness of diverse networks can be improved dramatically while their functionality remains unchanged. Our results are useful not only for improving significantly with low cost the robustness of existing infrastructures but also for designing economically robust network systems.

  9. Unitizing worker expertise and maximizing the brain reward centers

    SciTech Connect (OSTI)

    Martinez, Anthony Bert [Los Alamos National Laboratory

    2010-01-01T23:59:59.000Z

    People are experts when it comes to the work they do; unfortunately their expertise is not utilized as frequently as it could be. More opportunities need to be provided that allow people to participate in the design of their work including: accident investigations, job planning, and process improvements. Many employers use some form of job hazard analysis process to identify and document hazards and controls, but the front line worker is rarely involved. This presentation will show the core principles supporting employee involvement, provide examples where workers had brilliant ideas but no one listened, and provide examples where workers were given the opportunity to use their expertise to improve occupational safety. According to Abraham Maslow's Hierarch of Needs model, one essential human need is to be innovative and solve problems. Advances in brain science have proven, through functional magnetic resonance imaging (fMRI) studies, the brain reward pathway is activated when people are recognized for their intellectual contributions. As people contribute their expertise to improve occupational safety more frequently they will feel a sense of gratification. In addition, safety professionals will have more time to spend on strategic planning of emerging occupational safety issues. One effect of the current global recession is that SH&E professionals are asked to do more with less. Therefore, to be successful it is essential that SH&E professionals incorporate worker expertise in job planning. This will be illustrated in the presentation through an example where a worker had the answer to a difficult decision on appropriate personal protective equipment for a job but no one asked the worker for his idea during the job planning phase. Fortunately the worker was eventually consulted and his recommendation for the appropriate personal protective equipment for the job was implemented before work began. The goal of this presentation is to expand the awareness and knowledge of SH&E professionals on the benefits and opportunities for leveraging brain science. This will include an overview of the components of the brain reward pathway and the biological mechanisms that make workers feel a sense of gratification when they contribute their ideas toward improving occupational safety. On-the-job examples where it is hypothesized that the brain reward pathway was activated in workers will be provided. Finally, the presentation will include a model illustrating the importance of empowering workers to participate in occupational safety programs. SH&E professionals can use this model to maintain a robust safety and health program with limited resources. The model will also help SH&E professionals prepare for challenges in the SH&E fields by showing them how to allocate more time for strategic planning of emerging issues. Many recent best selling business books such as Wikinomics, Crowdsourcing, and Sway, illustrate how the benefit of harnessing the collective knowledge of employees is a key to company success. Companies like Google and Pixar have mastered the ability to capture empFoyee knowledge in terms of technology. Why should occupational safety be any different? Workers know how to improve safety in their workplace. SH&E professionals can harness this collective safety knowledge just as top companies do with technology, and workers will feel grateful for contributing.

  10. Sensor networks for social networks

    E-Print Network [OSTI]

    Farry, Michael P. (Michael Patrick)

    2006-01-01T23:59:59.000Z

    This thesis outlines the development of software that makes use of Bayesian belief networks and signal processing techniques to make meaningful inferences about real-world phenomena using data obtained from sensor networks. ...

  11. Storageflow: An SDN Approach to Storage Networks

    E-Print Network [OSTI]

    Bose, Pradipta

    2014-08-04T23:59:59.000Z

    and support for experimentation. Additionally, there is a significant potential to improve the performance of the system by leveraging regenerative coding techniques and by allowing the intermediate network nodes to perform encoding operations. OpenFlow (OF...

  12. Cicada: Predictive Guarantees for Cloud Network Bandwidth

    E-Print Network [OSTI]

    LaCurts, Katrina

    2014-03-24T23:59:59.000Z

    In cloud-computing systems, network-bandwidth guarantees have been shown to improve predictability of application performance and cost. Most previous work on cloud-bandwidth guarantees has assumed that cloud tenants know ...

  13. The role of whole brain radiation therapy in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline

    E-Print Network [OSTI]

    2010-01-01T23:59:59.000Z

    MANUSCRIPT The role of whole brain radiation therapy in themanagement of newly diagnosed brain metastases: a systematicNeurosurgery, Iowa Spine and Brain Institute, Iowa City, IA,

  14. Brain-derived neurotrophic factor genotype is associated with brain gray and white matter tissue volumes recovery in abstinent alcohol-dependent individuals

    E-Print Network [OSTI]

    Mon, A; Durazzo, TC; Gazdzinski, S; Hutchison, KE; Pennington, DL; Meyerhoff, DJ

    2013-01-01T23:59:59.000Z

    PA Author Manuscript Genes Brain Behav. Author manuscript;TH. Association between brain-derived neurotrophic factorgene polymorphism and progressive brain volume changes in

  15. Treatment of Five or More Brain Metastases With Stereotactic Radiosurgery

    SciTech Connect (OSTI)

    Hunter, Grant K.; Suh, John H.; Reuther, Alwyn M. [Department of Radiation Oncology, Cleveland Clinic, Cleveland, OH (United States)] [Department of Radiation Oncology, Cleveland Clinic, Cleveland, OH (United States); Vogelbaum, Michael A.; Barnett, Gene H.; Angelov, Lilyana; Weil, Robert J. [Department of Neurosurgery, Cleveland Clinic, Cleveland, OH (United States)] [Department of Neurosurgery, Cleveland Clinic, Cleveland, OH (United States); Neyman, Gennady [Department of Radiation Oncology, Cleveland Clinic, Cleveland, OH (United States)] [Department of Radiation Oncology, Cleveland Clinic, Cleveland, OH (United States); Chao, Samuel T., E-mail: chaos@ccf.org [Department of Radiation Oncology, Cleveland Clinic, Cleveland, OH (United States)

    2012-08-01T23:59:59.000Z

    Purpose: To examine the outcomes of patients with five or more brain metastases treated in a single session with stereotactic radiosurgery (SRS). Methods and Materials: Sixty-four patients with brain metastases treated with SRS to five or more lesions in a single session were reviewed. Primary disease type, number of lesions, Karnofsky performance score (KPS) at SRS, and status of primary and systemic disease at SRS were included. Patients were treated using dosing as defined by Radiation Therapy Oncology Group Protocol 90-05, with adjustments for critical structures. We defined prior whole-brain radiotherapy (WBRT) as WBRT completed >1 month before SRS and concurrent WBRT as WBRT completed within 1 month before or after SRS. Kaplan-Meier estimates and Cox proportional hazard regression were used to determine which patient and treatment factors predicted overall survival (OS). Results: The median OS after SRS was 7.5 months. The median KPS was 80 (range, 60-100). A KPS of {>=}80 significantly influenced OS (median OS, 4.8 months for KPS {<=}70 vs. 8.8 months for KPS {>=}80, p = 0.0097). The number of lesions treated did not significantly influence OS (median OS, 6.6 months for eight or fewer lesions vs. 9.9 months for more than eight, p = nonsignificant). Primary site histology did not significantly influence median OS. On multivariate Cox modeling, KPS and prior WBRT significantly predicted for OS. Whole-brain radiotherapy before SRS compared with concurrent WBRT significantly influenced survival, with a risk ratio of 0.423 (95% confidence interval 0.191-0.936, p = 0.0338). No significant differences were observed when no WBRT was compared with concurrent WBRT or when the no WBRT group was compared with prior WBRT. A KPS of {<=}70 predicted for poorer outcomes, with a risk ratio of 2.164 (95% confidence interval 1.157-4.049, p = 0.0157). Conclusions: Stereotactic radiosurgery to five or more brain lesions is an effective treatment option for patients with metastatic cancer, especially for patients previously treated with WBRT. A KPS of {>=}80 predicts for an improved outcome.

  16. ORIGINAL PAPER Social Networks Help Control Hypertension

    E-Print Network [OSTI]

    Gleeson, Joseph G.

    ORIGINAL PAPER Social Networks Help Control Hypertension Fadia T. Shaya, PhD, MPH;1 Viktor V administered within social networks on the improvement of hypertension in 248 African Americans compared with historical controls. Patients formed clusters with peers and attended monthly hypertension education sessions

  17. Time-Critical Data Delivery in Wireless Sensor Networks

    E-Print Network [OSTI]

    Roedig, Utz

    early, the network may spend these resources to improve transmission reliability or energy consumption to conserve energy and not to support timely data transmission. This paper shows how WSNs can be dimensioned and control. A network wide transmission schedule is determined before network #12;deployment, ensuring

  18. Percolation in Transparent and Conducting Carbon Nanotube Networks

    E-Print Network [OSTI]

    Gruner, George

    and chemical sensors9 , field emission devices10,11 , and transparent conductive coatings7 . We12 , and another. Transmission measurements also indicate the usefulness of nanotube network films as a transparent, conductive coating. Avenues for improvement of the network transparency are discussed. KEYWORDS Nanotubes, Networks

  19. Network Coding for Joint Storage and Transmission with Minimum Cost

    E-Print Network [OSTI]

    Jiang, Anxiao "Andrew"

    transmission and data storage in networks. Its power comes from the improved flexibility that codeword symbolsNetwork Coding for Joint Storage and Transmission with Minimum Cost Anxiao (Andrew) Jiang@cs.tamu.edu. Abstract-- Network coding provides elegant solutions to many data transmission problems. The usage

  20. ECN Marking for Congestion Control in Multihop Wireless Networks

    E-Print Network [OSTI]

    Siris, Vasilios A.

    ECN Marking for Congestion Control in Multihop Wireless Networks Vasilios A. Siris and Despina an approach to increase TCP's fair- ness in multihop wireless networks, using ECN as a congestion signalling demonstrate that our approach can improve TCP's fairness in a multihop wireless network compared to drop tail

  1. Finding and Mending Barrier Gaps in Wireless Sensor Networks

    E-Print Network [OSTI]

    Liu, Benyuan

    Finding and Mending Barrier Gaps in Wireless Sensor Networks Anwar Saipulla Benyuan Liu Jie Wang--Constructing sensing barriers using wireless sensor networks has important applications in military operations results show that our algorithms can effectively improve the barrier coverage of a wireless sensor network

  2. Position Estimation With Moving Beacons in Wireless Sensor Networks

    E-Print Network [OSTI]

    Dong, Liang

    Position Estimation With Moving Beacons in Wireless Sensor Networks Liang Dong and Frank L nodes in a wireless sensor network. Without GPS capability on any of the sensors, the position issue in wireless sensor networks. Accurate positions of sensor nodes improve the routing efficiency

  3. Cross-layered Synchronization Protocol for Wireless Sensor Networks

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Cross-layered Synchronization Protocol for Wireless Sensor Networks Thomas Beluch, Daniela. Advances in wireless sensor network performances and improvement of attainable bit rates allow research on such measurement systems using Wireless Sensor Networks (WSNs). However, current WSN synchronization protocols do

  4. Cognitive Radio Networks as Sensor Networks

    E-Print Network [OSTI]

    Bandari, Dorna; Yang, Seung R.; Zhao, Yue; Pottie, Gregory

    2007-01-01T23:59:59.000Z

    assuming the cognitive radios know their own coordinates.Networked Sensing Cognitive Radio Networks As SensorIntroduction: Cognitive Radio (CR) Networks The Need For

  5. Pinning impulsive control algorithms for complex network

    SciTech Connect (OSTI)

    Sun, Wen [School of Information and Mathematics, Yangtze University, Jingzhou 434023 (China)] [School of Information and Mathematics, Yangtze University, Jingzhou 434023 (China); Lü, Jinhu [Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing 100190 (China)] [Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing 100190 (China); Chen, Shihua [College of Mathematics and Statistics, Wuhan University, Wuhan 430072 (China)] [College of Mathematics and Statistics, Wuhan University, Wuhan 430072 (China); Yu, Xinghuo [School of Electrical and Computer Engineering, RMIT University, Melbourne VIC 3001 (Australia)] [School of Electrical and Computer Engineering, RMIT University, Melbourne VIC 3001 (Australia)

    2014-03-15T23:59:59.000Z

    In this paper, we further investigate the synchronization of complex dynamical network via pinning control in which a selection of nodes are controlled at discrete times. Different from most existing work, the pinning control algorithms utilize only the impulsive signals at discrete time instants, which may greatly improve the communication channel efficiency and reduce control cost. Two classes of algorithms are designed, one for strongly connected complex network and another for non-strongly connected complex network. It is suggested that in the strongly connected network with suitable coupling strength, a single controller at any one of the network's nodes can always pin the network to its homogeneous solution. In the non-strongly connected case, the location and minimum number of nodes needed to pin the network are determined by the Frobenius normal form of the coupling matrix. In addition, the coupling matrix is not necessarily symmetric or irreducible. Illustrative examples are then given to validate the proposed pinning impulsive control algorithms.

  6. Network Based Evaluation Method for Financial Analysis of Toll Roads

    E-Print Network [OSTI]

    Vajdic, Nevena

    2011-02-22T23:59:59.000Z

    the network improvement actions add to the complexity of these agreements. The objective of this research is to develop a method which will allow an assessment of the effect that network improvement actions have on the project’s financial feasibility. Three...

  7. A Brain-Switch using Riemannian Geometry A. Barachant1

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    A Brain-Switch using Riemannian Geometry A. Barachant1 , S. Bonnet1 , M. Congedo2 , C. Jutten2 1 the issue of asynchronous brain-switch. The detection of a specific brain pattern from the ongoing EEG-time EEG segments contain all the desired information. Such a brain-switch is valuable as it is easy to set

  8. Brain donation is one of the most important contributions to

    E-Print Network [OSTI]

    Contractor, Anis

    01-19-09 Brain donation is one of the most important contributions to research. Brain donations 200 brain tissue samples to researchers. Some of the major findings that came about through utilization of this precious gift include: In 2006, Todd Preuss and his team showed that certain brain

  9. Volume 10, No. 1 Decade of the Brain

    E-Print Network [OSTI]

    Dolbow, John

    Winter 2014 Volume 10, No. 1 SHINING A LIGHT ON BRAIN INJURY Decade of the Brain #12;ALSO of traumatic brain injury in children 14 "Hypoxia in a box" may reveal hidden concussion damage 18 Diabetes Clark, MSN'11, builds hope and health in Uganda Decade of the BRAIN #12;From 1990 through 2000, the U

  10. The brain: What is critical about it? Dante R. Chialvo

    E-Print Network [OSTI]

    Chialvo, Dante R.

    The brain: What is critical about it? Dante R. Chialvo , Pablo Balenzuela and Daniel Fraiman the recent proposal that the most fascinating brain properties are related to the fact that it always stays results, as well as further implications of this view of the functioning brain. Keywords: Brain, critical

  11. Zo Rebecca Hunter Plasticity of the adult human brain

    E-Print Network [OSTI]

    Kallenrode, May-Britt

    Zoë Rebecca Hunter Plasticity of the adult human brain and motor recovery after stroke PICS © Institute of Cognitive Science #12;1 Bachelor's Thesis Plasticity of the adult human brain and motor brain and motor recovery after stroke 2 Abstract Stroke may cause a major destruction of brain tissue

  12. Doppler Ultrasound Driven Biomechanical Model of the Brain for

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Doppler Ultrasound Driven Biomechanical Model of the Brain for Intraoperative Brain of the target is essential to reduce mor- bidity during brain tumor removal interventions. Yet, image-guided neu- rosurgery faces an important issue for large skull openings where brain soft-tissues can exhibit large

  13. Norme Attuative della Cognitive and Brain Sciences Doctoral School

    E-Print Network [OSTI]

    1 Norme Attuative della Cognitive and Brain Sciences Doctoral School Executive Regulations of the Cognitive and Brain Sciences Doctoral School Norme Attuative della Scuola di Dottorato in Cognitive and Brain Sciences Executive Regulations of the Cognitive and Brain Sciences Doctoral School Approvate nella

  14. Multipinhole collimator with 20 apertures for a brain SPECT application

    SciTech Connect (OSTI)

    Lee, Tzu-Cheng; Ellin, Justin R.; Shrestha, Uttam; Seo, Youngho, E-mail: youngho.seo@ucsf.edu [Physics Research Laboratory, Department of Radiology and Biomedical Imaging, University of California, San Francisco, California 94107 (United States); Huang, Qiu [School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030 (China); Gullberg, Grant T. [Department of Radiotracer Development and Imaging Technology, Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94702 (United States)

    2014-11-01T23:59:59.000Z

    Purpose: Several new technologies for single photon emission computed tomography (SPECT) instrumentation with parallel-hole collimation have been proposed to improve detector sensitivity and signal collection efficiency. Benefits from improved signal efficiency include shorter acquisition times and lower dose requirements. In this paper, the authors show a possibility of over an order of magnitude enhancement in photon detection efficiency (from 7.6 × 10{sup ?5} to 1.6 × 10{sup ?3}) for dopamine transporter (DaT) imaging of the striatum over the conventional SPECT parallel-hole collimators by use of custom-designed 20 multipinhole (20-MPH) collimators with apertures of 0.75 cm diameter. Methods: Quantifying specific binding ratio (SBR) of {sup 123}I-ioflupane or {sup 123}I-iometopane’s signal at the striatal region is a common brain imaging method to confirm the diagnosis of the Parkinson’s disease. The authors performed imaging of a striatal phantom filled with aqueous solution of I-123 and compared camera recovery ratios of SBR acquired between low-energy high-resolution (LEHR) parallel-hole collimators and 20-MPH collimators. Results: With only two-thirds of total acquisition time (20 min against 30 min), a comparable camera recovery ratio of SBR was achieved using 20-MPH collimators in comparison to that from the LEHR collimator study. Conclusions: Their systematic analyses showed that the 20-MPH collimator could be a promising alternative for the DaT SPECT imaging for brain over the traditional LEHR collimator, which could give both shorter scan time and improved diagnostic accuracy.

  15. Continuous Time Bayesian Network Approximate Inference and Social Network Applications

    E-Print Network [OSTI]

    Fan, Yu

    2009-01-01T23:59:59.000Z

    Modeling Social Network Dynamics . . . . . . . . . . . .85 Social Network Dynamic85 Static Social Network Models . . . . . . . . . . . . .

  16. An Extended Network Coding Opportunity Discovery Scheme in Wireless Networks

    E-Print Network [OSTI]

    Zhao, Yunlong; Iwai, Masayuki; Sezaki, Kaoru; Tobe, Yoshito; 10.5121/ijcnc.2012.4106

    2012-01-01T23:59:59.000Z

    Network coding is known as a promising approach to improve wireless network performance. How to discover the coding opportunity in relay nodes is really important for it. There are more coding chances, there are more times it can improve network throughput by network coding operation. In this paper, an extended network coding opportunity discovery scheme (ExCODE) is proposed, which is realized by appending the current node ID and all its 1-hop neighbors' IDs to the packet. ExCODE enables the next hop relay node to know which nodes else have already overheard the packet, so it can discover the potential coding opportunities as much as possible. ExCODE expands the region of discovering coding chance to n-hops, and have more opportunities to execute network coding operation in each relay node. At last, we implement ExCODE over the AODV protocol, and efficiency of the proposed mechanism is demonstrated with NS2 simulations, compared to the existing coding opportunity discovery scheme.

  17. Where Brain, Body and World Collide 

    E-Print Network [OSTI]

    Clark, Andy

    1998-01-01T23:59:59.000Z

    The brain fascinates because it is the biological organ of mindfulness itself. It is the inner engine that drives intelligent behavior. Such a depiction provides a worthy antidote to the once-popular vision of the mind as ...

  18. Nanotools for Neuroscience and Brain Activity Mapping

    E-Print Network [OSTI]

    Alivisatos, A. Paul

    Neuroscience is at a crossroads. Great effort is being invested into deciphering specific neural interactions and circuits. At the same time, there exist few general theories or principles that explain brain function. We ...

  19. BE 780: Brain Machine Interfaces Spring 2013

    E-Print Network [OSTI]

    Vajda, Sandor

    BE 780: Brain Machine Interfaces Spring 2013 Instructor: Jason Ritt the readings for an assigned class. Homework 30% Mid-semester Report 30, code, or files of any kind. Reports and final projects must

  20. Brain Cluster Leiden -InventoryBrain Cluster Leiden -Inventory Inventory of organizations working inInventory of organizations working in

    E-Print Network [OSTI]

    Galis, Frietson

    Brain Cluster Leiden - InventoryBrain Cluster Leiden - Inventory Inventory of organizations working brain Annelieke Hoenderkamp Leiden Bio Science Park foundation in assignment of Municipality of Leiden November 2011 #12;IntroductionIntroduction · The brain is the most complex organ in the human body. Its

  1. Improved Microseismicity Detection During Newberry EGS Stimulations

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Templeton, Dennise

    Effective enhanced geothermal systems (EGS) require optimal fracture networks for efficient heat transfer between hot rock and fluid. Microseismic mapping is a key tool used to infer the subsurface fracture geometry. Traditional earthquake detection and location techniques are often employed to identify microearthquakes in geothermal regions. However, most commonly used algorithms may miss events if the seismic signal of an earthquake is small relative to the background noise level or if a microearthquake occurs within the coda of a larger event. Consequently, we have developed a set of algorithms that provide improved microearthquake detection. Our objective is to investigate the microseismicity at the DOE Newberry EGS site to better image the active regions of the underground fracture network during and immediately after the EGS stimulation. Detection of more microearthquakes during EGS stimulations will allow for better seismic delineation of the active regions of the underground fracture system. This improved knowledge of the reservoir network will improve our understanding of subsurface conditions, and allow improvement of the stimulation strategy that will optimize heat extraction and maximize economic return.

  2. Improved Microseismicity Detection During Newberry EGS Stimulations

    SciTech Connect (OSTI)

    Templeton, Dennise

    2013-11-01T23:59:59.000Z

    Effective enhanced geothermal systems (EGS) require optimal fracture networks for efficient heat transfer between hot rock and fluid. Microseismic mapping is a key tool used to infer the subsurface fracture geometry. Traditional earthquake detection and location techniques are often employed to identify microearthquakes in geothermal regions. However, most commonly used algorithms may miss events if the seismic signal of an earthquake is small relative to the background noise level or if a microearthquake occurs within the coda of a larger event. Consequently, we have developed a set of algorithms that provide improved microearthquake detection. Our objective is to investigate the microseismicity at the DOE Newberry EGS site to better image the active regions of the underground fracture network during and immediately after the EGS stimulation. Detection of more microearthquakes during EGS stimulations will allow for better seismic delineation of the active regions of the underground fracture system. This improved knowledge of the reservoir network will improve our understanding of subsurface conditions, and allow improvement of the stimulation strategy that will optimize heat extraction and maximize economic return.

  3. Improved Microseismicity Detection During Newberry EGS Stimulations

    SciTech Connect (OSTI)

    Templeton, Dennise

    2013-10-01T23:59:59.000Z

    Effective enhanced geothermal systems (EGS) require optimal fracture networks for efficient heat transfer between hot rock and fluid. Microseismic mapping is a key tool used to infer the subsurface fracture geometry. Traditional earthquake detection and location techniques are often employed to identify microearthquakes in geothermal regions. However, most commonly used algorithms may miss events if the seismic signal of an earthquake is small relative to the background noise level or if a microearthquake occurs within the coda of a larger event. Consequently, we have developed a set of algorithms that provide improved microearthquake detection. Our objective is to investigate the microseismicity at the DOE Newberry EGS site to better image the active regions of the underground fracture network during and immediately after the EGS stimulation. Detection of more microearthquakes during EGS stimulations will allow for better seismic delineation of the active regions of the underground fracture system. This improved knowledge of the reservoir network will improve our understanding of subsurface conditions, and allow improvement of the stimulation strategy that will optimize heat extraction and maximize economic return.

  4. Brain Research and DLM: An overview 

    E-Print Network [OSTI]

    Irby, Beverly J.; Lara-Alecio, Rafael

    2010-10-22T23:59:59.000Z

    of months of age, babies can process the emotional contours of language (prosody), which means they tune in to the emotional variations in your voice. (In fact, toddlers can memorize nursery rhymes because rhymes have prosody!) As the preschool teacher... time periods (Markezich, n.d.) So, what does this mean? ? The brain knows how to developmentally scaffold itself. For example, in Broca's area, the region in the brain for language production, it has been determined that when this becomes...

  5. Optimization of the Energy Efficiency of a Hybrid Broadcast/Unicast Network

    E-Print Network [OSTI]

    Boyer, Edmond

    Optimization of the Energy Efficiency of a Hybrid Broadcast/Unicast Network Nicolas Cornillet previously defined, we propose a new operating mode for the hybrid network that can improve the energy a particular attention. In [1], a model for a hybrid network is introduced. This network consists in the inter

  6. NetworksNetworks andand hypernetworkshypernetworks 33

    E-Print Network [OSTI]

    Vilela Mendes, Rui

    NetworksNetworks andand hypernetworkshypernetworks 33 NetworksNetworks inin economyeconomy Rui.1 #12;TheThe networksnetworks ofof thethe corporatecorporate eliteelite TheThe Elite 16Elite 16 inin informationinformation inin thethe networknetwork !! CorporateCorporate governancegovernance practicespractices

  7. Routing in hybrid networks

    E-Print Network [OSTI]

    Gupta, Avinash

    2001-01-01T23:59:59.000Z

    Hybrid networks are networks that have wired as well as wireless components. Several routing protocols exist for traditional wired networks and mobile ad-hoc networks. However, there are very few routing protocols designed for hybrid networks...

  8. PACAP Interactions in the Mouse Brain: Implications for Behavioral and Other Disorders

    SciTech Connect (OSTI)

    Acquaah-Mensah, George; Taylor, Ronald C.; Bhave, Sanjiv V.

    2012-01-10T23:59:59.000Z

    As an activator of adenylate cyclase, the neuropeptide Pituitary Adenylate Cyclase Activating Peptide (PACAP) impacts levels of cyclic AMP, a key second messenger available in brain cells. PACAP is involved in certain adult behaviors. To elucidate PACAP interactions, a compendium of microarrays representing mRNA expression in the adult mouse whole brain was pooled from the Phenogen database for analysis. A regulatory network was computed based on mutual information between gene pairs using gene expression data across the compendium. Clusters among genes directly linked to PACAP, and probable interactions between corresponding proteins were computed. Database 'experts' affirmed some of the inferred relationships. The findings suggest ADCY7 is probably the adenylate cyclase isoform most relevant to PACAP's action. They also support intervening roles for kinases including GSK3B, PI 3-kinase, SGK3 and AMPK. Other high-confidence interactions are hypothesized for future testing. This new information has implications for certain behavioral and other disorders.

  9. Spontaneous synchronization driven by energy transport in interconnected networks

    E-Print Network [OSTI]

    Vincenzo Nicosia; Per Sebastian Skardal; Vito Latora; Alex Arenas

    2015-02-26T23:59:59.000Z

    Understanding dynamical processes on networks is an important area of research in complex systems, with far reaching implications and applications in many real-world cases. Here we introduce and study a model of intertwined dynamics on interconnected networks, inspired by the human brain, which consists of bidirectionally coupled synchronization and energy transport processes. Remarkably, the proposed model allows the emergence of spontaneous switch-like synchronization transitions driven by the energy transport dynamics, which qualitatively mirror the transitions observed in human brain dynamics between resting-state and cognitive activity. We provide a steady-state analytical explanation for the observed behavior and show that the switch-like transition is robust over a wide range of model parameters and network topologies. Finally, we suggest that the complexity inherent in other interconnected dynamical processes might be responsible for various other emergent behaviors observed in natural systems.

  10. Peer-to-Peer Networks Social Networks

    E-Print Network [OSTI]

    Marbach, Peter

    Overview Peer-to-Peer Networks Social Networks Research Hybrid Peer-to-Peer Networks P2P and Online Social Networks: The Best Has Yet to Come Peter Marbach, Dept. of Computer Science University of Toronto P2P and Online Social Networks: The Best Has Yet to Come #12;Overview Peer-to-Peer Networks Social

  11. Bayesian Discovery of Threat Networks

    E-Print Network [OSTI]

    Smith, Steven T; Senne, Kenneth D; Bernstein, Garrett; Philips, Scott

    2013-01-01T23:59:59.000Z

    A novel unified Bayesian framework for network detection is developed, under which a detection algorithm is derived based on random walks on graphs. The algorithm detects threat networks using partial observations of their activity, and is proved to be optimum in the Neyman-Pearson sense. The algorithm is defined by a graph, at least one observation, and a diffusion model for threat. A link to well-known spectral detection methods is provided, and the equivalence of the random walk and harmonic solutions to the Bayesian formulation is proven. A general diffusion model is introduced that utilizes spatio-temporal relationships between vertices, and is used for a specific space-time formulation that leads to significant performance improvements on coordinated covert networks. This performance is demonstrated using a new hybrid interaction model introduced to simulate random covert networks with realistic properties.

  12. BRAIN, BEHAVIOUR AND NEUROIMAGING A seminar to create awareness about the mysteries of the brain

    E-Print Network [OSTI]

    Narayanan, H.

    BRAIN, BEHAVIOUR AND NEUROIMAGING A seminar to create awareness about the mysteries of the brain Srinivasan Professor & Head, Centre of Behavioural and Cognitive Sciences, University of Allahabad.D. Head of Department, Physiology, S.M.S. Medical College, Jaipur Psychology and Police investigations Mr

  13. Across-Peer Rate Allocation Algorithm in Peer-to-peer Networks

    E-Print Network [OSTI]

    Su, Yang

    2013-05-30T23:59:59.000Z

    We introduce a new across-peer rate allocation algorithm with successive refinement to improve the video transmission performance in P2P networks, based on the combination of multiple description coding and network coding. Successive refinement...

  14. Successive structuring of source coding algorithms for data fusion, buffering, and distribution in networks

    E-Print Network [OSTI]

    Draper, Stark Christiaan

    2002-01-01T23:59:59.000Z

    Numerous opportunities to improve network performance present themselves when we make communication networks aware of the characteristics of the data content they are handling. In this thesis, we design such content-aware ...

  15. New therapeutic targets in Alzheimer's disease: brain deregulation of calcium and zinc

    E-Print Network [OSTI]

    Corona, C; Pensalfini, A; Frazzini, V; Sensi, S L

    2011-01-01T23:59:59.000Z

    39;s disease: brain deregulation of calcium and zinc [39;s disease: brain deregulation of calcium and zinc39;s disease: brain deregulation of calcium and zinc Gotz

  16. Understanding Why Patients Return to the Emergency Department after Mild Traumatic Brain Injury within 72 Hours

    E-Print Network [OSTI]

    2015-01-01T23:59:59.000Z

    patients with minimal brain injury and small intracranialelements for traumatic brain injury: a population study. Intcenter for mild traumatic brain injury. Neurosurgical Focus.

  17. System and method for networking electrochemical devices

    DOE Patents [OSTI]

    Williams, Mark C. (Morgantown, WV); Wimer, John G. (Morgantown, WV); Archer, David H. (Pittsburgh, PA)

    1995-01-01T23:59:59.000Z

    An improved electrochemically active system and method including a plurality of electrochemical devices, such as fuel cells and fluid separation devices, in which the anode and cathode process-fluid flow chambers are connected in fluid-flow arrangements so that the operating parameters of each of said plurality of electrochemical devices which are dependent upon process-fluid parameters may be individually controlled to provide improved operating efficiency. The improvements in operation include improved power efficiency and improved fuel utilization in fuel cell power generating systems and reduced power consumption in fluid separation devices and the like through interstage process fluid parameter control for series networked electrochemical devices. The improved networking method includes recycling of various process flows to enhance the overall control scheme.

  18. miRNAs in brain development

    SciTech Connect (OSTI)

    Petri, Rebecca; Malmevik, Josephine; Fasching, Liana; Åkerblom, Malin; Jakobsson, Johan, E-mail: johan.jakobsson@med.lu.se

    2014-02-01T23:59:59.000Z

    MicroRNAs (miRNAs) are small, non-coding RNAs that negatively regulate gene expression at the post-transcriptional level. In the brain, a large number of miRNAs are expressed and there is a growing body of evidence demonstrating that miRNAs are essential for brain development and neuronal function. Conditional knockout studies of the core components in the miRNA biogenesis pathway, such as Dicer and DGCR8, have demonstrated a crucial role for miRNAs during the development of the central nervous system. Furthermore, mice deleted for specific miRNAs and miRNA-clusters demonstrate diverse functional roles for different miRNAs during the development of different brain structures. miRNAs have been proposed to regulate cellular functions such as differentiation, proliferation and fate-determination of neural progenitors. In this review we summarise the findings from recent studies that highlight the importance of miRNAs in brain development with a focus on the mouse model. We also discuss the technical limitations of current miRNA studies that still limit our understanding of this family of non-coding RNAs and propose the use of novel and refined technologies that are needed in order to fully determine the impact of specific miRNAs in brain development. - Highlights: • miRNAs are essential for brain development and neuronal function. • KO of Dicer is embryonically lethal. • Conditional Dicer KO results in defective proliferation or increased apoptosis. • KO of individual miRNAs or miRNA families is necessary to determine function.

  19. Brain Receptor Structures Key to Future Therapeutics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041clothAdvanced Materials Advanced Materials Find FindRewindParticleBorncelebrates itsBradyBrainBrain

  20. Economic Improvement Districts (Indiana)

    Broader source: Energy.gov [DOE]

    A legislative body may adopt an ordinance establishing an economic improvement district and an Economic Improvement Board to manage development in a respective district. The Board can choose to...

  1. BigNeuron: Unlocking the Secrets of the Human Brain

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    BigNeuron: Unlocking the Secrets of the Human Brain BigNeuron: Unlocking the Secrets of the Human Brain Berkeley Researchers and Supercomputers to Help Create a Standard 3D Neuron...

  2. The formation and function of the brain ventricular system

    E-Print Network [OSTI]

    Chang, Jessica T. (Jessica Tzung-Min)

    2012-01-01T23:59:59.000Z

    The brain ventricular system is composed of a highly conserved set of cavities that contain cerebrospinal fluid (CSF), a protein-rich fluid essential for brain function. However, little is known about the function of ...

  3. 9.14 Brain Structure and Its Origins, Spring 2009

    E-Print Network [OSTI]

    Schneider, Gerald E.

    Outline of mammalian functional neuroanatomy, aided by studies of comparative neuroanatomy and evolution, and of brain development. Topics include early steps to a central nervous system, basic patterns of brain and spinal ...

  4. Improving supply chain resilience

    E-Print Network [OSTI]

    Leung, Elsa Hiu Man

    2009-01-01T23:59:59.000Z

    Due to the global expansion of Company A's supply chain network, it is becoming more vulnerable to many disruptions. These disruptions often incur additional costs; and require time to respond to and recover from these ...

  5. Proceedings of the Neural Network Workshop for the Hanford Community

    SciTech Connect (OSTI)

    Keller, P.E.

    1994-01-01T23:59:59.000Z

    These proceedings were generated from a series of presentations made at the Neural Network Workshop for the Hanford Community. The abstracts and viewgraphs of each presentation are reproduced in these proceedings. This workshop was sponsored by the Computing and Information Sciences Department in the Molecular Science Research Center (MSRC) at the Pacific Northwest Laboratory (PNL). Artificial neural networks constitute a new information processing technology that is destined within the next few years, to provide the world with a vast array of new products. A major reason for this is that artificial neural networks are able to provide solutions to a wide variety of complex problems in a much simpler fashion than is possible using existing techniques. In recognition of these capabilities, many scientists and engineers are exploring the potential application of this new technology to their fields of study. An artificial neural network (ANN) can be a software simulation, an electronic circuit, optical system, or even an electro-chemical system designed to emulate some of the brain`s rudimentary structure as well as some of the learning processes that are believed to take place in the brain. For a very wide range of applications in science, engineering, and information technology, ANNs offer a complementary and potentially superior approach to that provided by conventional computing and conventional artificial intelligence. This is because, unlike conventional computers, which have to be programmed, ANNs essentially learn from experience and can be trained in a straightforward fashion to carry out tasks ranging from the simple to the highly complex.

  6. Differeneces in Brain Responses Between Lean and Obese Women to a Sweetened Drink

    E-Print Network [OSTI]

    Connolly, Lynn Shapiro

    2012-01-01T23:59:59.000Z

    Activation in brain energy regulation and reward centers byActivation in brain energy regulation and reward centers by

  7. Chemically-selective imaging of brain structures with CARS microscopy

    E-Print Network [OSTI]

    Xie, Xiaoliang Sunney

    Chemically-selective imaging of brain structures with CARS microscopy Conor L. Evans1§ , Xiaoyin Xu anti-Stokes Raman scattering (CARS) microscopy to image brain structure and pathology ex vivo. Although. Definitive diagnosis still requires brain biopsy in a significant number of cases. CARS microscopy

  8. DISCOVERING BRAIN MECHANISMS AND THE RULES OF MOLECULAR

    E-Print Network [OSTI]

    Stengel, Robert F.

    DISCOVERING BRAIN MECHANISMS AND THE RULES OF MOLECULAR BIOLOGY Paul Shapshak, PhD*1 and Robert-324-2723 ABSTRACT The human genome has approximately 30,000 genes. Brain cells express at least 15,000. The human brain is subject to many acute and chronic diseases including viral encephalitis, AIDS/HIV Associated

  9. Human brain cancer studied by resonance Raman spectroscopy

    E-Print Network [OSTI]

    Sun, Yi

    Human brain cancer studied by resonance Raman spectroscopy Yan Zhou Cheng-Hui Liu Yi Sun Yang Pu://biomedicaloptics.spiedigitallibrary.org/ on 11/16/2012 Terms of Use: http://spiedl.org/terms #12;Human brain cancer studied by resonance Raman of human brain tissues are examined using a confocal micro-Raman system with 532-nm excitation in vitro

  10. and the Brain Sound may seem a straightforward physical phenom-

    E-Print Network [OSTI]

    Hill, Wendell T.

    Hearing and the Brain Sound may seem a straightforward physical phenom- enon, whose waves can be recorded, charted and parsed. But no machines can do what the human brain does--understand a wide variety of electrical and computer engineering and member of the Institute for Systems Research, studies how the brain

  11. Traumatic Brain Injury Dr Seena Fazel & Prof. Huw Williams

    E-Print Network [OSTI]

    Mumby, Peter J.

    Traumatic Brain Injury and Crime Dr Seena Fazel & Prof. Huw Williams NHS Centre for Clinical Neuropsychological Research (CCNR) #12;Traumatic Brain Injury (TBI) Moderate-Severe TBI (e.g. 30 mins + LoC) ­ insult to the brain from an external mechanical force. ­ E.g. blow to the head - "fast- stop" in a crash

  12. The brain near the edge Dante R. Chialvo

    E-Print Network [OSTI]

    Chialvo, Dante R.

    The brain near the edge Dante R. Chialvo Department of Physiology, Feinberg Medical School grain, the brain seems a relatively small dynamical system composed by a few dozen interacting areas that some of the most fundamental properties of the functioning brain are possible because

  13. Brain donation is one of the most important contributions to

    E-Print Network [OSTI]

    Contractor, Anis

    01-19-09 Brain donation is one of the most important contributions to research. As researchers work to better understand disorders that affect mental function with aging, brain donations are essential to their progress. By studying the anatomy, pathology, and chemistry of the brains of people with memory problems

  14. BRAIN AND SURFACE WARPING VIA MINIMIZING LIPSCHITZ EXTENSIONS

    E-Print Network [OSTI]

    BRAIN AND SURFACE WARPING VIA MINIMIZING LIPSCHITZ EXTENSIONS By Facundo M´emoli Guillermo Sapiro­0436 Phone: 612/624-6066 Fax: 612/626-7370 URL: http://www.ima.umn.edu #12;Brain and Surface Warping via connection with the infinity Laplacian, a computational framework for surface warping and in particular brain

  15. ELSEVIER Brain Research 712 (1996) 293-298 Research report

    E-Print Network [OSTI]

    Tepper, James M.

    BRAIN RESEARCH ELSEVIER Brain Research 712 (1996) 293-298 Research report Local infusion of brain examined the effects of local infusion of BDNF on the electrophysioiogical activity of serotonergic neurons in the rat dorsal raph6 nucleus with extracellular single unit recording in vivo. Compared with vehicle-infused

  16. UNSUPERVISED SEGMENTATION FOR AUTOMATIC DETECTION OF BRAIN TUMORS IN MRI

    E-Print Network [OSTI]

    Lefèvre, Sébastien

    a pre-segmentation to ex- tract the brain from the head. Then, a second segmentation is done insideUNSUPERVISED SEGMENTATION FOR AUTOMATIC DETECTION OF BRAIN TUMORS IN MRI A.S. Capelle, O. Alata, C- thod for magnetic resonance images. The aim of this seg- mentation is to divide the brain

  17. Computational Simulation and Visualization of Traumatic Brain Injuries

    E-Print Network [OSTI]

    Burtscher, Martin

    brain tissue oscillations shed new light on the mechanisms of Closed Head Injuries. Our results may helpComputational Simulation and Visualization of Traumatic Brain Injuries Martin Burtscher School the human brain dynamics in realistic 2D cross-sections during trau- matic scenarios corresponding

  18. XRDS summer 2010 Vol .16 No.442 From Brains

    E-Print Network [OSTI]

    Jacob, Robert J.K.

    XRDS · summer 2010 · Vol .16 · No.442 From Brains to Bytes Although most people are likely all-powerful, BCI research. In the past year, University of Wisconsin-Madison's Brain-Twitter in- terface received Time Magazine's honor as the no. 9 invention of the year. Fur- thermore, as brain

  19. Intra-operative Registration for Deep Brain Stimulation Procedures

    E-Print Network [OSTI]

    Boyer, Edmond

    Intra-operative Registration for Deep Brain Stimulation Procedures based on a Full Physics Head´e Rennes I Abstract. Brain deformation is a factor of inaccuracy during stereo- tactic neurosurgeries to update the pre-operative planning based on a physical simulation of the brain shift. A minimization

  20. ORIGINAL ARTICLE Early Brain Overgrowth in Autism Associated

    E-Print Network [OSTI]

    Utah, University of

    ORIGINAL ARTICLE Early Brain Overgrowth in Autism Associated With an Increase in Cortical Surface, PhD; Chad Chappell, MA; Rachel Gimpel Smith, BA; Clement Vachet, MS; Joseph Piven, MD Context: Brain. Objective: To investigate early growth trajectories in brain volume and cortical thickness. Design

  1. Computational Modeling of Brain Dynamics during Repetitive Head Motions

    E-Print Network [OSTI]

    Burtscher, Martin

    Computational Modeling of Brain Dynamics during Repetitive Head Motions Igor Szczyrba School the HIC scale to arbitrary head motions. Our simulations of the brain dynamics in sagittal and horizontal injury modeling, resonance effects 1 Introduction A rapid head motion can result in a severe brain injury

  2. Numerical Modeling of Brain Dynamics in Traumatic Situations -Impulsive Translations

    E-Print Network [OSTI]

    Burtscher, Martin

    .S.A. Abstract We numerically model the brain dy- namics during and after impulsive head translations using brain injuries appear among boxers and shaken babies despite minimal rotations of their heads. Modeling head translations also helps understand the brain dynamics during head rotations about an arbitrary

  3. Development of an Interhemispheric Symmetry Measurement in the Neonatal Brain

    E-Print Network [OSTI]

    Development of an Interhemispheric Symmetry Measurement in the Neonatal Brain Ninah Koolen1.dereymaeker, katrien.jansen, jan.vervisch, gunnar.naulaers}@uzleuven.be Keywords: Preterm Brain, Symmetry, Channel of different brain regions will allow detecting physiologic asymmetry versus pathologic asymmetry. This can

  4. POSTER PRESENTATION Open Access Spatiotemporal dynamics in the human brain

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    POSTER PRESENTATION Open Access Spatiotemporal dynamics in the human brain during rest: a virtual brain study Andreas Spiegler* , Enrique Hansen, Viktor K Jirsa From Twenty Second Annual Computational Neuroscience Meeting: CNS*2013 Paris, France. 13-18 July 2013 Over the past years the ongoing human brain

  5. Brain (1999), 122, 839854 Electrophysiological manifestations of open-and

    E-Print Network [OSTI]

    Coulson, Seana

    Brain (1999), 122, 839­854 Electrophysiological manifestations of open- and closed-class words in patients with Broca's aphasia with agrammatic comprehension An event-related brain potential study Mariken-related brain potentials were recorded from the scalp when Broca patients and non- aphasic control subjects were

  6. Probing the brain’s white matter with diffusion MRI and a tissue dependent diffusion model 

    E-Print Network [OSTI]

    Piatkowski, Jakub Przemyslaw

    2014-06-27T23:59:59.000Z

    While diffusion MRI promises an insight into white matter microstructure in vivo, the axonal pathways that connect different brain regions together can only partially be segmented using current methods. Here we present ...

  7. Possible new wave phenomena in the brain

    E-Print Network [OSTI]

    Jerzy Szwed

    2009-08-10T23:59:59.000Z

    We propose to search for new wave phenomena in the brain by using interference effects in analogy to the well-known double slit (Young) experiment. This method is able to extend the range of oscillation frequencies to much higher values than currently accessible. It is argued that such experiments may test the hypothesis of the wave nature of information coding.

  8. Woodpecker pecking: how woodpeckers avoid brain injury

    E-Print Network [OSTI]

    Gibson, Lorna

    Woodpeckers are capable of repeated pecking on a tree at remarkably high decelerations (on the order of 10 000 m s?2 or 1000 g). In this paper, I re-examine previous studies of pecking and scaling effects in brain injury. ...

  9. Research Article Human Brain Activity Time-

    E-Print Network [OSTI]

    Zacks, Jeffrey M.

    Research Article Human Brain Activity Time- Locked to Narrative Event Boundaries Nicole K. Speer to or reading descriptions of everyday activities (e.g., reading about a person making cookies; Speer & Zacks, 2005; Speer, Zacks, & Reynolds, 2006). These findings are not altogether surprising given theories

  10. Experimental Brain Research ISSN 0014-4819

    E-Print Network [OSTI]

    Rosen, Jacob

    of speeds Matt Simkins, Anne Burleigh Jacobs & Jacob Rosen #12;1 3 Exp Brain Res (2013) 229:517­524 DOI 10 of speeds Matt Simkins · Anne Burleigh Jacobs · Jacob Rosen Received: 1 April 2013 / Accepted: 9 June 2013 motion. M. Simkins (*) · J. Rosen Department of Computer Engineering, University of California, Santa

  11. Modeling oscillatory dynamics in brain microcircuits as a way to help uncover neurological disease mechanisms: A proposal

    SciTech Connect (OSTI)

    Skinner, F. K. [Toronto Western Research Institute, University Health Network, Krembil Discovery Tower, Toronto Western Hospital, 60 Leonard Street, 7th floor, 7KD411, Toronto, Ontario M5T 2S8 (Canada) [Toronto Western Research Institute, University Health Network, Krembil Discovery Tower, Toronto Western Hospital, 60 Leonard Street, 7th floor, 7KD411, Toronto, Ontario M5T 2S8 (Canada); Department of Medicine (Neurology), University of Toronto, 200 Elizabeth Street, Toronto, Ontario M5G 2C4 (Canada); Department of Physiology, University of Toronto Medical Sciences Building, 3rd Floor, 1 King's College Circle, Toronto, Ontario M5S 1A8 (Canada); Ferguson, K. A. [Toronto Western Research Institute, University Health Network, Krembil Discovery Tower, Toronto Western Hospital, 60 Leonard Street, 7th floor, 7KD411, Toronto, Ontario M5T 2S8 (Canada) [Toronto Western Research Institute, University Health Network, Krembil Discovery Tower, Toronto Western Hospital, 60 Leonard Street, 7th floor, 7KD411, Toronto, Ontario M5T 2S8 (Canada); Department of Physiology, University of Toronto Medical Sciences Building, 3rd Floor, 1 King's College Circle, Toronto, Ontario M5S 1A8 (Canada)

    2013-12-15T23:59:59.000Z

    There is an undisputed need and requirement for theoretical and computational studies in Neuroscience today. Furthermore, it is clear that oscillatory dynamical output from brain networks is representative of various behavioural states, and it is becoming clear that one could consider these outputs as measures of normal and pathological brain states. Although mathematical modeling of oscillatory dynamics in the context of neurological disease exists, it is a highly challenging endeavour because of the many levels of organization in the nervous system. This challenge is coupled with the increasing knowledge of cellular specificity and network dysfunction that is associated with disease. Recently, whole hippocampus in vitro preparations from control animals have been shown to spontaneously express oscillatory activities. In addition, when using preparations derived from animal models of disease, these activities show particular alterations. These preparations present an opportunity to address challenges involved with using models to gain insight because of easier access to simultaneous cellular and network measurements, and pharmacological modulations. We propose that by developing and using models with direct links to experiment at multiple levels, which at least include cellular and microcircuit, a cycling can be set up and used to help us determine critical mechanisms underlying neurological disease. We illustrate our proposal using our previously developed inhibitory network models in the context of these whole hippocampus preparations and show the importance of having direct links at multiple levels.

  12. Distributed Scalable Network Association in Wireless Sensor Networks Hyung-Sin Kim, Jin-Seok Han, Jae-Seok Bang, and Yong-Hwan Lee

    E-Print Network [OSTI]

    Bahk, Saewoong

    @snu.ac.kr Abstract--Wireless sensor networks (WSNs) need to employ a network association mechanism that can securely centralized and broadcasting based network association mechanisms may consume large energy, and distributed of the proposed scheme is evaluated by computer simulation, showing remarkable performance improvement over

  13. Abstract -Other researchers have proposed that the brain parenchymal fraction (or brain atrophy) may be a good surrogate

    E-Print Network [OSTI]

    Orchard, Jeffery J.

    head MRI scans. An automatic segmentation method for the brain and for the cerebral spinal fluid measure of brain atrophy automatically from head MRI scans acquired as 5mm thick axial slices. We were from the head in MRI scans [5]. The brain mask is obtained by anisotropic diffusion of the T2 image

  14. EXCELLENTIA CoLumbIA ENgINEErINg22 eople suffering from brain diseases and conditions ranging from traumatic brain

    E-Print Network [OSTI]

    Hone, James

    HEALTH EXCELLENTIA CoLumbIA ENgINEErINg22 P eople suffering from brain diseases and conditions ranging from traumatic brain injury to brain cancer to progressive brain disorders could be helped if therapeu- tic drugs could be easily delivered to the affected areas. The blood-brain barrier (BBB

  15. In: Proceedings of SPIE Conference on Medical Imaging (4684), pp. 201-205, Feb. 2002. Robustness of the Brain Parenchymal Fraction for Measuring Brain

    E-Print Network [OSTI]

    Orchard, Jeffery J.

    -echo PD and T2-weighted head MRI scans. The robustness of the brain parenchymal fraction is evaluated of the Brain Parenchymal Fraction for Measuring Brain Atrophy M. Stella Atkins, Jeff J. Orchard, Ben Law ABSTRACT Other researchers have proposed that the brain parenchymal fraction (or brain atrophy) may

  16. 1/12/11 1:51 PMComputer-Aided Brains: Scientific American Page 1 of 3http://www.scientificamerican.com/article.cfm?id=computer-aided-brains

    E-Print Network [OSTI]

    Salvucci, Dario D.

    » Scientific American Mind » October 2005 Head Lines | Mind & Brain Computer-Aided Brains By Brad Stenger1/12/11 1:51 PMComputer-Aided Brains: Scientific American Page 1 of 3http://www.scientificamerican.com/article.cfm?id=computer-aided-brains Image: For years, innovators have tried to devise computerized gadgetry to aid the brain. Advances have

  17. Transformation of Networks through Cognitive Approaches

    E-Print Network [OSTI]

    Nair, T R Gopalakrishnan; Sooda, Kavitha

    2010-01-01T23:59:59.000Z

    The growth in data traffic and the increased demand for quality of service has meant current network systems need to be more efficient. The introduction of improved routing systems to meet the increasing demand and varied protocols to accommodate various scales of challenges in network efficiency has further complicated the operations. This means a better mode of intelligence had to be infused into networking for smoother operations and better autonomic features. Cognitive networks are defined and analyzed in this angle. They are identified to have the potential to deal with the future user related quality and efficiency of service at optimized levels. The cognitive elements of system like perception, learning, planning, reasoning and decision forming can enable the systems to be more aware of their environment and offer better services. These approaches are expected to transform the mode of operation of future networks.

  18. Innovation flow through social networks: Productivity distribution

    E-Print Network [OSTI]

    T. Di Matteo; T. Aste; M. Gallegati

    2004-06-19T23:59:59.000Z

    A detailed empirical analysis of the productivity of non financial firms across several countries and years shows that productivity follows a non-Gaussian distribution with power law tails. We demonstrate that these empirical findings can be interpreted as consequence of a mechanism of exchanges in a social network where firms improve their productivity by direct innovation or/and by imitation of other firm's technological and organizational solutions. The type of network-connectivity determines how fast and how efficiently information can diffuse and how quickly innovation will permeate or behaviors will be imitated. From a model for innovation flow through a complex network we obtain that the expectation values of the productivity level are proportional to the connectivity of the network of links between firms. The comparison with the empirical distributions reveals that such a network must be of a scale-free type with a power-law degree distribution in the large connectivity range.

  19. A Phase 3 Trial of Whole Brain Radiation Therapy and Stereotactic Radiosurgery Alone Versus WBRT and SRS With Temozolomide or Erlotinib for Non-Small Cell Lung Cancer and 1 to 3 Brain Metastases: Radiation Therapy Oncology Group 0320

    SciTech Connect (OSTI)

    Sperduto, Paul W., E-mail: psperduto@mropa.com [Metro MN CCOP, Minneapolis, Minnesota (United States); Wang, Meihua [RTOG Statistical Center, Philadelphia, Pennsylvania (United States)] [RTOG Statistical Center, Philadelphia, Pennsylvania (United States); Robins, H. Ian [University of Wisconsin Medical School Cancer Center, Madison, Wisconsin (United States)] [University of Wisconsin Medical School Cancer Center, Madison, Wisconsin (United States); Schell, Michael C. [Wilmot Cancer Center, University of Rochester, Rochester, New York (United States)] [Wilmot Cancer Center, University of Rochester, Rochester, New York (United States); Werner-Wasik, Maria [Thomas Jefferson University, Philadelphia, Pennsylvania (United States)] [Thomas Jefferson University, Philadelphia, Pennsylvania (United States); Komaki, Ritsuko [University of Texas MD Anderson Cancer Center, Houston, Texas (United States)] [University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Souhami, Luis [McGill University, Montreal, Quebec (Canada)] [McGill University, Montreal, Quebec (Canada); Buyyounouski, Mark K. [Fox Chase Cancer Center, Philadelphia, Pennsylvania (United States)] [Fox Chase Cancer Center, Philadelphia, Pennsylvania (United States); Khuntia, Deepak [University of Wisconsin Hospital, Madison, Wisconsin (United States)] [University of Wisconsin Hospital, Madison, Wisconsin (United States); Demas, William [Akron City Hospital, Akron, Ohio (United States)] [Akron City Hospital, Akron, Ohio (United States); Shah, Sunjay A. [Christiana Care Health Services, Inc, CCOP, Newark, Delaware (United States)] [Christiana Care Health Services, Inc, CCOP, Newark, Delaware (United States); Nedzi, Lucien A. [University of Texas Southwestern Medical School, Dallas, Texas (United States)] [University of Texas Southwestern Medical School, Dallas, Texas (United States); Perry, Gad [The Ottawa Hospital Cancer Centre, Ottawa, Ontario (Canada)] [The Ottawa Hospital Cancer Centre, Ottawa, Ontario (Canada); Suh, John H. [Cleveland Clinic Foundation, Cleveland, Ohio (United States)] [Cleveland Clinic Foundation, Cleveland, Ohio (United States); Mehta, Minesh P. [Northwestern Memorial Hospital, Chicago, Illinois (United States)] [Northwestern Memorial Hospital, Chicago, Illinois (United States)

    2013-04-01T23:59:59.000Z

    Background: A phase 3 Radiation Therapy Oncology Group (RTOG) study subset analysis demonstrated improved overall survival (OS) with the addition of stereotactic radiosurgery (SRS) to whole brain radiation therapy (WBRT) in non-small cell lung cancer (NSCLC) patients with 1 to 3 brain metastases. Because temozolomide (TMZ) and erlotinib (ETN) cross the blood-brain barrier and have documented activity in NSCLC, a phase 3 study was designed to test whether these drugs would improve the OS associated with WBRT + SRS. Methods and Materials: NSCLC patients with 1 to 3 brain metastases were randomized to receive WBRT (2.5 Gy × 15 to 37.5 Gy) and SRS alone, versus WBRT + SRS + TMZ (75 mg/m{sup 2}/day × 21 days) or ETN (150 mg/day). ETN (150 mg/day) or TMZ (150-200 mg/m{sup 2}/day × 5 days/month) could be continued for as long as 6 months after WBRT + SRS. The primary endpoint was OS. Results: After 126 patients were enrolled, the study closed because of accrual limitations. The median survival times (MST) for WBRT + SRS, WBRT + SRS + TMZ, and WBRT + SRS + ETN were qualitatively different (13.4, 6.3, and 6.1 months, respectively), although the differences were not statistically significant. Time to central nervous system progression and performance status at 6 months were better in the WBRT + SRS arm. Grade 3 to 5 toxicity was 11%, 41%, and 49% in arms 1, 2, and 3, respectively (P<.001). Conclusion: The addition of TMZ or ETN to WBRT + SRS in NSCLC patients with 1 to 3 brain metastases did not improve survival and possibly had a deleterious effect. Because the analysis is underpowered, these data suggest but do not prove that increased toxicity was the cause of inferior survival in the drug arms.

  20. Dosimetric Comparison Between 3DCRT and IMRT Using Different Multileaf Collimators in the Treatment of Brain Tumors

    SciTech Connect (OSTI)

    Ding Meisong [Radiation Oncology Department, University of Colorado Heath Science Center, Aurora, CO (United States)], E-mail: Meisong.Ding@uchsc.edu; Newman, Francis M.S.; Chen Changhu; Stuhr, Kelly; Gaspar, Laurie E. [Radiation Oncology Department, University of Colorado Heath Science Center, Aurora, CO (United States)

    2009-04-01T23:59:59.000Z

    We investigated the differences between 3-dimensional conformal radiotherapy (3DCRT) and intensity modulated radiotherapy (IMRT), and the impact of collimator leaf-width on IMRT plans for the treatment of nonspherical brain tumors. Eight patients treated by 3DCRT with Novalis were selected. We developed 3 IMRT plans with different multileaf collimators (Novalis m3, Varian MLC-120, and Varian MLC-80) with the same treatment margins, number of beams, and gantry positions as in the 3DCRT treatment plans. Treatment planning utilized the BrainLAB treatment planning system. For each patient, the dose constraints and optimization parameters remained identical for all plans. The heterogeneity index, the percentage target coverage, critical structures, and normal tissue volumes receiving 50% of the prescription dose were calculated to compare the dosimetric difference. Equivalent uniform dose (EUD) and tumor control probability (TCP) were also introduced to evaluate the radiobiological effect for different plans. We found that IMRT significantly improved the target dose homogeneity compared to the 3DCRT. However, IMRT showed the same radiobiological effect as 3DCRT. For the brain tumors adjacent to (or partially overlapping with) critical structures, IMRT dramatically spared the volume of the critical structures to be irradiated. In IMRT plans, the smaller collimator leaf width could reduce the volume of critical structures irradiated to the 50% level for those partially overlapping with the brain tumors. For relatively large and spherical brain tumors, the smaller collimator leaf widths give no significant benefit.

  1. Secure and efficient wireless networks

    E-Print Network [OSTI]

    Bellardo, John Michael

    2006-01-01T23:59:59.000Z

    CA Systems and Network Administrator California Integrationgives the campus network administrators complete admissionin engineered networks, enterprise administrators try to

  2. A Phase I Study of Short-Course Accelerated Whole Brain Radiation Therapy for Multiple Brain Metastases

    SciTech Connect (OSTI)

    Caravatta, Luciana; Deodato, Francesco; Ferro, Marica [Department of Radiation Oncology, Fondazione di Ricerca e Cura 'Giovanni Paolo II', Universita Cattolica del S. Cuore, Campobasso (Italy)] [Department of Radiation Oncology, Fondazione di Ricerca e Cura 'Giovanni Paolo II', Universita Cattolica del S. Cuore, Campobasso (Italy); Macchia, Gabriella, E-mail: gmacchia@rm.unicatt.it [Department of Radiation Oncology, Fondazione di Ricerca e Cura 'Giovanni Paolo II', Universita Cattolica del S. Cuore, Campobasso (Italy)] [Department of Radiation Oncology, Fondazione di Ricerca e Cura 'Giovanni Paolo II', Universita Cattolica del S. Cuore, Campobasso (Italy); Massaccesi, Mariangela [Department of Radiation Oncology, Fondazione di Ricerca e Cura 'Giovanni Paolo II', Universita Cattolica del S. Cuore, Campobasso (Italy)] [Department of Radiation Oncology, Fondazione di Ricerca e Cura 'Giovanni Paolo II', Universita Cattolica del S. Cuore, Campobasso (Italy); Cilla, Savino [Medical Physics Unit, Fondazione di Ricerca e Cura 'Giovanni Paolo II,' Universita Cattolica del S. Cuore, Campobasso (Italy)] [Medical Physics Unit, Fondazione di Ricerca e Cura 'Giovanni Paolo II,' Universita Cattolica del S. Cuore, Campobasso (Italy); Padula, Gilbert D.A. [Department of Radiation Oncology, The Lacks Cancer Center Saint Mary's Health Care, Grand Rapids, Michigan (United States)] [Department of Radiation Oncology, The Lacks Cancer Center Saint Mary's Health Care, Grand Rapids, Michigan (United States); Mignogna, Samantha; Tambaro, Rosa [Department of Palliative Therapies, Fondazione di Ricerca e Cura 'Giovanni Paolo II', Universita Cattolica del S. Cuore, Campobasso (Italy)] [Department of Palliative Therapies, Fondazione di Ricerca e Cura 'Giovanni Paolo II', Universita Cattolica del S. Cuore, Campobasso (Italy); Carrozza, Francesco [Department of Oncology, A. Cardarelli Hospital, Campobasso (Italy)] [Department of Oncology, A. Cardarelli Hospital, Campobasso (Italy); Flocco, Mariano [Madre Teresa di Calcutta Hospice, Larino (Italy)] [Madre Teresa di Calcutta Hospice, Larino (Italy); Cantore, Giampaolo [Department of Neurological Sciences, Istituto Neurologico Mediterraneo Neuromed, Istituto di Ricovero e Cura a Carattere Scientifico, Pozzilli (Italy)] [Department of Neurological Sciences, Istituto Neurologico Mediterraneo Neuromed, Istituto di Ricovero e Cura a Carattere Scientifico, Pozzilli (Italy); Scapati, Andrea [Department of Radiation Oncology, 'San Francesco' Hospital, Nuoro (Italy)] [Department of Radiation Oncology, 'San Francesco' Hospital, Nuoro (Italy); Buwenge, Milly [Department of Radiotherapy, Mulago Hospital, Kampala (Uganda)] [Department of Radiotherapy, Mulago Hospital, Kampala (Uganda); and others

    2012-11-15T23:59:59.000Z

    Purpose: To define the maximum tolerated dose (MTD) of a SHort-course Accelerated whole brain RadiatiON therapy (SHARON) in the treatment of patients with multiple brain metastases. Methods and Materials: A phase 1 trial in 4 dose-escalation steps was designed: 12 Gy (3 Gy per fraction), 14 Gy (3.5 Gy per fraction), 16 Gy (4 Gy per fraction), and 18 Gy (4.5 Gy per fraction). Eligibility criteria included patients with unfavorable recursive partitioning analysis (RPA) class > or =2 with at least 3 brain metastases or metastatic disease in more than 3 organ systems, and Eastern Cooperative Oncology Group (ECOG) performance status {<=}3. Treatment was delivered in 2 days with twice-daily fractionation. Patients were treated in cohorts of 6-12 to define the MTD. The dose-limiting toxicity (DLT) was defined as any acute toxicity {>=}grade 3, according to the Radiation Therapy Oncology Group scale. Information on the status of the main neurologic symptoms and quality of life were recorded. Results: Characteristics of the 49 enrolled patients were as follows: male/female, 30/19; median age, 66 years (range, 23-83 years). ECOG performance status was <3 in 46 patients (94%). Fourteen patients (29%) were considered to be in recursive partitioning analysis (RPA) class 3. Grade 1-2 acute neurologic (26.4%) and skin (18.3%) toxicities were recorded. Only 1 patient experienced DLT (neurologic grade 3 acute toxicity). With a median follow-up time of 5 months (range, 1-23 months), no late toxicities have been observed. Three weeks after treatment, 16 of 21 symptomatic patients showed an improvement or resolution of presenting symptoms (overall symptom response rate, 76.2%; confidence interval 0.95: 60.3-95.9%). Conclusions: Short-course accelerated radiation therapy in twice-daily fractions for 2 consecutive days is tolerated up to a total dose of 18 Gy. A phase 2 study has been planned to evaluate the efficacy on overall survival, symptom control, and quality of life indices.

  3. Speed Training: Improving the Rate of Backpropagation Learning through Stochastic Sample Presentation

    E-Print Network [OSTI]

    Martinez, Tony R.

    Speed Training: Improving the Rate of Backpropagation Learning through Stochastic Sample. However, using complex neural networks to learn very large training sets is often problematic, imposing prohibitive time constraints on the training process. We present four practical methods for dramatically

  4. Integrated assessment of quality of supply in future electricity networks 

    E-Print Network [OSTI]

    Hernando Gil, Ignacio

    2014-11-27T23:59:59.000Z

    Although power system reliability analysis is a mature research area, there is a renewed interest in updating available network models and formulating improved reliability assessment procedures. The main driver of this ...

  5. Interconnecting PV on New York City's Secondary Network Distribution System

    SciTech Connect (OSTI)

    Anderson, K.; Coddington, M.; Burman, K.; Hayter, S.; Kroposki, B.; Watson, A.

    2009-12-01T23:59:59.000Z

    This study describes technical assistance provided by NREL to help New York City and Con Edison improve the interconnection of distributed PV systems on a secondary network distribution system.

  6. ability runs deep: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    detection methods we demonstrate improved ability to identify important communities and key members in the network. Chen, Pin-Yu 2014-01-01 14 (DIS)ABILITY Fosteringacultureof...

  7. Adaptive sampling and forecasting with mobile sensor networks

    E-Print Network [OSTI]

    Choi, Han-Lim

    2009-01-01T23:59:59.000Z

    This thesis addresses planning of mobile sensor networks to extract the best information possible out of the environment to improve the (ensemble) forecast at some verification region in the future. To define the information ...

  8. Digital neural network-based modeling technique for extrusion processes

    E-Print Network [OSTI]

    Jang, Won-Hyouk

    2001-01-01T23:59:59.000Z

    and market conditions. In order to develop reliable and well-performing advanced process monitoring and diagnostic systems for achieving improved product quality and cost-effective operation, the neural network-based modeling technique for the extrusion...

  9. Cooperative Network Coding Next Generation Technology for Today's Warfighter

    E-Print Network [OSTI]

    Haas, Zygmunt J.

    Communications to produce superior network reliability and provide inherent security features, while improving it towards the next cluster. 3.Nodes, in cluster 2 through K, receive the combination packets and act as MISO

  10. autori uis olte: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Websites Summary: The Why UI: Using Goal Networks to Improve User Interfaces Dustin A. Smith MIT Media Lab 20 Ames St; Cambridge, MA 02139 dustin@media.mit.edu Henry Lieberman...

  11. Thermoacoustic tomography arising in brain imaging

    E-Print Network [OSTI]

    Stefanov, Plamen

    2010-01-01T23:59:59.000Z

    We study the mathematical model of thermoacoustic and photoacoustic tomography when the sound speed has a jump across a smooth surface. This models the change of the sound speed in the skull when trying to image the human brain. We derive an explicit inversion formula in the form of a convergent Neumann series under the assumptions that all singularities from the support of the source reach the boundary.

  12. Thermoacoustic tomography arising in brain imaging

    E-Print Network [OSTI]

    Plamen Stefanov; Gunther Uhlmann

    2010-09-09T23:59:59.000Z

    We study the mathematical model of thermoacoustic and photoacoustic tomography when the sound speed has a jump across a smooth surface. This models the change of the sound speed in the skull when trying to image the human brain. We derive an explicit inversion formula in the form of a convergent Neumann series under the assumptions that all singularities from the support of the source reach the boundary.

  13. Copyright ! 2009 200902-Social Networking for Sustainable Building Practices

    E-Print Network [OSTI]

    Lepech, Michael D.

    these stakeholders as a living community that must work together to improve the sustainability of buildings over allCopyright ! 2009 200902- Social Networking for Sustainable Building Practices CIFE TAC 2009 1 Social Networking for Sustainable Building Practices CIFE Proposal 200902 PIs: Mike Lepech, Martin

  14. On Top-k Recommendation using Social Networks Xiwang Yang

    E-Print Network [OSTI]

    Liu, Yong

    On Top-k Recommendation using Social Networks Xiwang Yang , Harald Steck ,Yang Guo and Yong Liu). Social network based top-k recommendation, which recom- mends to a user a small number of items at a time, is not well studied. In this paper, we conduct a comprehensive study on improving the accuracy of top

  15. APAWSAN: Actor Positioning for Aerial Wireless Sensor and Actor Networks

    E-Print Network [OSTI]

    Turgut, Damla

    to be autonomous during deployment. The recent advances in development of small unmanned aerial vehicles (UAVs stations can improve network performance measures such as energy consumption and traffic load balancing vehicles (UAVs) with built in sensors made it possible to deploy aerial sensor and actor networks

  16. TR-IIS-11-004 An Integrated Network Mobility

    E-Print Network [OSTI]

    Chen, Sheng-Wei

    TR-IIS-11-004 An Integrated Network Mobility Management and Call Admission Control Scheme/tr11.html #12;An Integrated Network Mobility Management and Call Admission Control Scheme improvements however, are clashing with similarly impressive achievements in smart mobile device technology

  17. Energy-Efficient Capacity Optimization in Wireless Networks

    E-Print Network [OSTI]

    Wang, Yu

    Energy-Efficient Capacity Optimization in Wireless Networks Lu Liu, Xianghui Cao, Yu Cheng, Lili Du capacity in the most energy-efficient manner over a general large-scale wireless network, say, a multi numerical results demonstrate the energy efficiency improvement by the proposed energy-efficient

  18. Reference Models and Incentive Regulation of Electricity Distribution Networks: An Evaluation of Sweden’s Network Performance Assessment Model (NPAM)

    E-Print Network [OSTI]

    Jamasb, Tooraj; Pollitt, Michael G.

    The world-wide electricity sector reforms have led to a search for alternative and innovative approaches to regulation to promote efficiency improvement in the natural monopoly electricity networks. A number of countries have used incentive...

  19. Brain-Computer Interfaces and Quantum Robots

    E-Print Network [OSTI]

    Eliano Pessa; Paola zizzi

    2009-09-08T23:59:59.000Z

    The actual (classical) Brain-Computer Interface attempts to use brain signals to drive suitable actuators performing the actions corresponding to subject's intention. However this goal is not fully reached, and when BCI works, it does only in particular situations. The reason of this unsatisfactory result is that intention cannot be conceived simply as a set of classical input-output relationships. It is therefore necessary to resort to quantum theory, allowing the occurrence of stable coherence phenomena, in turn underlying high-level mental processes such as intentions and strategies. More precisely, within the context of a dissipative Quantum Field Theory of brain operation it is possible to introduce generalized coherent states associated, within the framework of logic, to the assertions of a quantum metalanguage. The latter controls the quantum-mechanical computing corresponding to standard mental operation. It thus become possible to conceive a Quantum Cyborg in which a human mind controls, through a quantum metalanguage, the operation of an artificial quantum computer.

  20. A Software Architecture for Physical Layer Wireless Network Emulation Glenn Judd and Peter Steenkiste

    E-Print Network [OSTI]

    Steenkiste, Peter

    to understanding and improving wireless networks has been the lack of a realistic yet flexible experimental methodology. Physical layer wireless network emulation promises to achieve much of the flexibility of wirelessA Software Architecture for Physical Layer Wireless Network Emulation Glenn Judd and Peter

  1. A Utility-based Multi-copy Forwarding Algorithm in Delay Tolerant Networks

    E-Print Network [OSTI]

    Wu, Jie

    cost. In this paper, we propose the first multi-copy utility-based opportunistic forwarding algorithm to improve the overall utility representing a user preferred trade-off between delay and forwarding cost so-space satellite networks, underwater acoustic buoy networks, and many dedicate networks for developing regions

  2. May 24, 2012 18:36 manuscript Data Processing using Artificial Neural Networks

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    May 24, 2012 18:36 manuscript Data Processing using Artificial Neural Networks to Improve uncertainties introduced by the 4D-CT scan, we conveniently treated data using artificial neural networks. More step are then used to build a training set for another artificial neural network that learns the lung

  3. Automatic classification of Sleep Stages on a EEG signal by Artificial Neural Networks

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Automatic classification of Sleep Stages on a EEG signal by Artificial Neural Networks Nizar of modeling and design to improve the performances of our tool. Key-Words: - Artificial Neural Networks data analysis tools. Concerning this latter point, we have proposed that Artificial Neural Networks

  4. Cross-Layer Enabled Translucent Optical Network with Real-time Impairment Awareness

    E-Print Network [OSTI]

    Politècnica de Catalunya, Universitat

    improvements in: (1) energy efficiency by optimizing the usage of regenerators, and (2) network performance and transparent networks, and therefore, to reduce costs and energy consumption in OTNs [6]. The existing to significant energy savings by optimizing the usage of regeneration resources, but also to network performance

  5. Fuzzy Trust Recommendation Based on Collaborative Filtering for Mobile Ad-hoc Networks

    E-Print Network [OSTI]

    Zhang, Yi

    Fuzzy Trust Recommendation Based on Collaborative Filtering for Mobile Ad-hoc Networks Junhai Luo1--Mobile ad-hoc networks (MANETs) are based on the cooperative and trust characteristic of the mobile nodes focused on building up trust among distributed network nodes to simulate cooperation and improving

  6. Case Studies—Financing Energy Improvements on Utility Bills

    Broader source: Energy.gov [DOE]

    Hosted by Technical Assistance Program (TAP), the State and Local Energy Efficiency Action Network (SEE Action), and Lawrence Berkeley National Laboratory's Electricity Market and Policy Group, this webinar was the second of a two-part webinar series focused on the new report, Financing Energy Improvements on Utility Bills: Market Updates and Key Program Design Considerations for Policymakers and Administrators.

  7. FLUID: Improving Throughputs in Enterprise Wireless LANs through Flexible Channelization

    E-Print Network [OSTI]

    Liblit, Ben

    the usefulness of flexible channels in the context of 802.11-based networks. Current 802.11 hardware can provideFLUID: Improving Throughputs in Enterprise Wireless LANs through Flexible Channelization Shravan for designing 802.11 wireless LANs (WLANs) using flexible channelization -- the choice of an appropriate channel

  8. On designing improved controllers for AQM routers supporting TCP ows

    E-Print Network [OSTI]

    Massachusetts at Amherst, University of

    On designing improved controllers for AQM routers supporting TCP ows #3; Chris Hollot 1 Vishal guidelines for designing stable controllers subject to network parameters like load level, propogation delay observed with RED. In [5], we performed a control theoretic analysis of a linearized model of TCP and RED

  9. Improving Attack Graph Visualization through Data Reduction and Attack Grouping

    E-Print Network [OSTI]

    Ou, Xinming "Simon"

    Improving Attack Graph Visualization through Data Reduction and Attack Grouping John Homer1 Laboratory, USA Abstract. Various tools exist to analyze enterprise network systems and to produce attack graphs detailing how attackers might penetrate into the system. These attack graphs, however, are often

  10. Double-ring network model of the head-direction system Xiaohui Xie,1,

    E-Print Network [OSTI]

    Xie, Xiaohui Sunney

    Double-ring network model of the head-direction system Xiaohui Xie,1, * Richard H. R. Hahnloser,1,2 and H. Sebastian Seung1,2 1 Department of Brain and Cognitive Sciences, Massachusetts Institute 2002; published 9 October 2002 In the head-direction system, the orientation of an animal's head

  11. Can we neglect the multi-layer structure of functional networks?

    E-Print Network [OSTI]

    Zanin, Massimiliano

    2015-01-01T23:59:59.000Z

    Functional networks, i.e. networks representing dynamic relationships between the components of a complex system, have been instrumental for our understanding of, among others, the human brain. Due to limited data availability, the multi-layer nature of numerous functional networks has hitherto been neglected, and nodes are endowed with a single type of links even when multiple relationships coexist at different physical levels. A relevant problem is the assessment of the benefits yielded by studying a multi-layer functional network, against the simplicity guaranteed by the reconstruction and use of the corresponding single layer projection. Here, I tackle this issue by using as a test case, the functional network representing the dynamics of delay propagation through European airports. Neglecting the multi-layer structure of a functional network has dramatic consequences on our understanding of the underlying system, a fact to be taken into account when a projection is the only available information.

  12. Combining a recurrent neural network and a PID controller for prognostic purpose

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Combining a recurrent neural network and a PID controller for prognostic purpose A way to improve Basis Function network (RRBF) and a proportional integral derivative controller (PID) is proposed in order to improve the accuracy of predictions. The PID controller attempts to correct the error between

  13. Collimator selection for SPECT brain imaging: the advantage of high resolution

    SciTech Connect (OSTI)

    Mueller, S.P.; Polak, J.F.; Kijewski, M.F.; Holman, B.L.

    1986-11-01T23:59:59.000Z

    We compared a prototype long-bore (LB) high-resolution collimator with a low-energy, general-purpose collimator (LEGP) using 99mTc and /sup 123/I. The LB collimator provided a 56% improvement in tomographic resolution (autocorrelation width) over the LEGP for 99mTc; for /sup 123/I, the gain was 79%, providing substantially improved contrast for small structures. The sensitivity of the LB collimator, however, is only 32% of that of the LEGP. The imaging tasks to be performed on (/sup 123/I)IMP brain scans involve localization and discrimination of small, high-contrast brain structures and detection of abnormalities in shape, size, or uptake, rather than simple detection of lesions. Observer performance in such higher-order imaging tasks is known to depend on high spatial resolution, even at the cost of sensitivity. Patient studies confirmed that, for resolution-limited tasks, the increase in resolution outweighs the increased noise due to a loss in sensitivity. When the tomographic resolution of the LB collimator was degraded by smoothing to that of the LEGP, the noise in the LB images was lower than that of the LEGP by a factor of 2.9 for the same imaging time, demonstrating the advantage of high-resolution detectors and a smooth reconstruction filter over low-resolution detectors without smoothing. Therefore, collimators designed for high resolution, even at substantial cost in sensitivity, are expected to yield significant improvements for brain SPECT. Geometric calculations show that commercially available low-energy, high-resolution cast collimators promise to meet these requirements.

  14. Network Embedded Systems Sensor Networks

    E-Print Network [OSTI]

    Amir, Yair

    Battery Energy Reserve Manager = Bank Each task requests an account with conditions W ­ fraction Tracking 9 #12;Virtual Battery: An Energy Reserve Abstraction for Embedded Sensor Networks Qing Cao of real battery allocated N ­ number of energy installments L ­ expected lifetime of the task C

  15. Improving Blood Brain Barrier Permeation of Small Molecules Exhibiting Chemotherapeutic and Neuroprotective Effects

    E-Print Network [OSTI]

    Desino, Kelly Elizabeth

    2008-05-06T23:59:59.000Z

    . Somerville, NJ) was used for the permeability studies described in the following chapters. This set up consists of two glass chambers surrounded by thermal jackets which are maintained by a circulating water bath. BBMECs are grown on polycarbonate... Figure 1.1 Schematic of the Side-bi-Side? diffusion apparatus (Ho et al., 1999) Permeability studies are conducted by filling the donor (luminal) and receiver (abluminal) chambers with PBSA (phosphate buffered saline supplemented with CaCl2, MgSO4...

  16. A new improved method for assessing brain deformation after decompressive craniectomy

    E-Print Network [OSTI]

    Fletcher, Tim L.; Kolias, Angelos G.; Hutchinson, Peter J. A.; Sutcliffe, Michael P. F.

    2014-10-10T23:59:59.000Z

    of the head and underwent a secondary DC operation (17 bifrontal and 10 unilateral craniectomies). Patients were ventilated and managed in the NCCU with a tiered therapeutic protocol aiming for an ICP, 25 mmHg and cerebral perfusion pressure (CPP) around 60... for bifrontal than unilateral cases. Supporting Information Table S1 Patient demography: * - no volume data, + - no displacement data. (PDF) Table S2 Modified Marshall CT grading system [10]. (PDF) Appendix S1 Gantry tilt correction. (PDF) Acknowledgments...

  17. Study of the brain connectivity in an Immersive Space Anne-Charlotte Philippe

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Study of the brain connectivity in an Immersive Space Anne-Charlotte Philippe ATHENA/INRIA Sophia of the brain connectivity. Both anatomical and functional data are attached to a mesh representing the brain the experience of the visualization of brain meshes in an immersive space for the specific study of brain con

  18. Automatic Scan Prescription for Brain MRI T. Ernst, L. Itti, L. Chang

    E-Print Network [OSTI]

    Itti, Laurent

    Automatic Scan Prescription for Brain MRI T. Ernst, L. Itti, L. Chang Harbor-UCLA Medical Center that allows the automatic prescription of brain MRI scans. This involves determination of the orientation of the current patient's brain, by matching his/her brain surface with a template brain surface. A desired

  19. Improving Fired Heater Efficiency 

    E-Print Network [OSTI]

    Shriver, J. E.

    1983-01-01T23:59:59.000Z

    1982. 2, Fehervari, Willi, "Gas Measurement and Control for Pipeline Systems," The Foxboro Company. 3. Shriver, James, "CO/02 Boiler Control: Point Is Vi tal," POWER, October 1982. Set 1\\. Dukelow, Samuel, "Improving Boiler Efficiency...

  20. Recent Improvements in DDT

    E-Print Network [OSTI]

    Edwards, D.J.

    1963-11-01T23:59:59.000Z

    This paper will report new developments and recent improvements to DDT. "Window DDT" now will remember undefined symbols and define them on a later command. Using sequence breaks, it can change the contents of memory while ...

  1. Abuse Tolerance Improvements

    Broader source: Energy.gov (indexed) [DOE]

    additive shows some improvement in flammability compared to the control electrolyte (EC:EMC (2:8)). Metal Phosphate-Coated Cathodes (PSI): Delivered 2 kg of LiMPO4-coated...

  2. Improved Dragline Utilization 

    E-Print Network [OSTI]

    Keller, K. J.

    1980-01-01T23:59:59.000Z

    The cause of energy conservation can be served by increasing the efficiency of large draglines used in surface coal mining. The topic is the application of a training simulator, computer instrumentation and computer simulation to improve dragline...

  3. Managing Energy Efficiency Improvement 

    E-Print Network [OSTI]

    Almaguer, J.

    2006-01-01T23:59:59.000Z

    results has been the utilization of Six Sigma methodology to identify and seize opportunities to improve our performance and to better meet customer needs. Since its implementation in 1999, Six Sigma has proven to be a breakthrough process that can... take Dow to the next level of performance for all our key stakeholders. The Six Sigma methodology has been especially successful in improving energy efficiency and reducing energy costs and is the primary methodology used by technology center...

  4. Chaotic physics in ferroelectrics hints at brain-like computing...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Oak Ridge National Laboratory 865-574-7308 Chaotic physics in ferroelectrics hints at brain-like computing Unexpected behavior in ferroelectric materials explored by researchers...

  5. Algorithms for enhanced spatiotemporal imaging of human brain function

    E-Print Network [OSTI]

    Krishnaswamy, Pavitra

    2014-01-01T23:59:59.000Z

    Studies of human brain function require technologies to non-invasively image neuronal dynamics with high spatiotemporal resolution. The electroencephalogram (EEG) and magnetoencephalogram (MEG) measure neuronal activity ...

  6. Pre-synaptic Lateral Inhibition Provides a Better Architecture for Self-Organising Neural Networks

    E-Print Network [OSTI]

    1999-01-01T23:59:59.000Z

    Unsupervised learning is an important property of the brain and of many artificial neural networks. A large variety of unsupervised learning algorithms have been proposed. This paper takes a different approach in considering the architecture of the neural network rather than the learning algorithm. It is shown that a self-organising neural network architecture using pre-synaptic lateral inhibition enables a single learning algorithm to find distributed, local, and topological representations as appropriate to the structure of the input data received. It is argued that such an architecture not only has computational advantages but is a better model of cortical self-organisation.

  7. What Is the Optimal Treatment of Large Brain Metastases? An Argument for a Multidisciplinary Approach

    SciTech Connect (OSTI)

    Choi, Clara Y.H.; Chang, Steven D. [Department of Neurosurgery, Stanford University Medical Center, Stanford, California (United States)] [Department of Neurosurgery, Stanford University Medical Center, Stanford, California (United States); Gibbs, Iris C. [Department of Radiation Oncology, Stanford University Medical Center, Stanford, California (United States)] [Department of Radiation Oncology, Stanford University Medical Center, Stanford, California (United States); Adler, John R.; Harsh, Griffith R. [Department of Neurosurgery, Stanford University Medical Center, Stanford, California (United States)] [Department of Neurosurgery, Stanford University Medical Center, Stanford, California (United States); Atalar, Banu [Department of Radiation Oncology, Acibadem University School of Medicine, Istanbul (Turkey)] [Department of Radiation Oncology, Acibadem University School of Medicine, Istanbul (Turkey); Lieberson, Robert E. [Department of Neurosurgery, Stanford University Medical Center, Stanford, California (United States)] [Department of Neurosurgery, Stanford University Medical Center, Stanford, California (United States); Soltys, Scott G., E-mail: sgsoltys@stanford.edu [Department of Radiation Oncology, Stanford University Medical Center, Stanford, California (United States)

    2012-11-01T23:59:59.000Z

    Purpose: Single-modality treatment of large brain metastases (>2 cm) with whole-brain irradiation, stereotactic radiosurgery (SRS) alone, or surgery alone is not effective, with local failure (LF) rates of 50% to 90%. Our goal was to improve local control (LC) by using multimodality therapy of surgery and adjuvant SRS targeting the resection cavity. Patients and Methods: We retrospectively evaluated 97 patients with brain metastases >2 cm in diameter treated with surgery and cavity SRS. Local and distant brain failure (DF) rates were analyzed with competing risk analysis, with death as a competing risk. The overall survival rate was calculated by the Kaplain-Meier product-limit method. Results: The median imaging follow-up duration for all patients was 10 months (range, 1-80 months). The 12-month cumulative incidence rates of LF, with death as a competing risk, were 9.3% (95% confidence interval [CI], 4.5%-16.1%), and the median time to LF was 6 months (range, 3-17 months). The 12-month cumulative incidence rate of DF, with death as a competing risk, was 53% (95% CI, 43%-63%). The median survival time for all patients was 15.6 months. The median survival times for recursive partitioning analysis classes 1, 2, and 3 were 33.8, 13.7, and 9.0 months, respectively (p = 0.022). On multivariate analysis, Karnofsky Performance Status ({>=}80 vs. <80; hazard ratio 0.54; 95% CI 0.31-0.94; p = 0.029) and maximum preoperative tumor diameter (hazard ratio 1.41; 95% CI 1.08-1.85; p = 0.013) were associated with survival. Five patients (5%) required intervention for Common Terminology Criteria for Adverse Events v4.02 grade 2 and 3 toxicity. Conclusion: Surgery and adjuvant resection cavity SRS yields excellent LC of large brain metastases. Compared with other multimodality treatment options, this approach allows patients to avoid or delay whole-brain irradiation without compromising LC.

  8. Gamma Knife Stereotactic Radiosurgery as Salvage Therapy After Failure of Whole-Brain Radiotherapy in Patients With Small-Cell Lung Cancer

    SciTech Connect (OSTI)

    Harris, Sunit [Department of Radiation Oncology, Wake Forest University, Winston-Salem, North Carolina (United States); Chan, Michael D., E-mail: mchan@wfubmc.edu [Department of Radiation Oncology, Wake Forest University, Winston-Salem, North Carolina (United States); Lovato, James F. [Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina (United States); Ellis, Thomas L.; Tatter, Stephen B. [Department of Neurosurgery, Wake Forest University, Winston-Salem, North Carolina (United States); Bourland, J. Daniel; Munley, Michael T.; Guzman, Allan F. de; Shaw, Edward G.; Urbanic, James J.; McMullen, Kevin P. [Department of Radiation Oncology, Wake Forest University, Winston-Salem, North Carolina (United States)

    2012-05-01T23:59:59.000Z

    Purpose: Radiosurgery has been successfully used in selected cases to avoid repeat whole-brain irradiation (WBI) in patients with multiple brain metastases of most solid tumor histological findings. Few data are available for the use of radiosurgery for small-cell lung cancer (SCLC). Methods and Materials: Between November 1999 and June 2009, 51 patients with SCLC and previous WBI and new brain metastases were treated with GammaKnife stereotactic radiosurgery (GKSRS). A median dose of 18 Gy (range, 10-24 Gy) was prescribed to the margin of each metastasis. Patients were followed with serial imaging. Patient electronic records were reviewed to determine disease-related factors and clinical outcomes after GKSRS. Local and distant brain failure rates, overall survival, and likelihood of neurologic death were determined based on imaging results. The Kaplan-Meier method was used to determine survival and local and distant brain control. Cox proportional hazard regression was performed to determine strength of association between disease-related factors and survival. Results: Median survival time for the entire cohort was 5.9 months. Local control rates at 1 and 2 years were 57% and 34%, respectively. Distant brain failure rates at 1 and 2 years were 58% and 75%, respectively. Fifty-three percent of patients ultimately died of neurologic death. On multivariate analysis, patients with stable (hazard ratio [HR] = 2.89) or progressive (HR = 6.98) extracranial disease (ECD) had worse overall survival than patients without evidence of ECD (p = 0.00002). Concurrent chemotherapy improved local control (HR = 89; p = 0.006). Conclusions: GKSRS represents a feasible salvage option in patients with SCLC and brain metastases for whom previous WBI has failed. The status of patients' ECD is a dominant factor predictive of overall survival. Local control may be inferior to that seen with other cancer histological results, although the use of concurrent chemotherapy may help to improve this.

  9. Whole Brain Irradiation With Hippocampal Sparing and Dose Escalation on Multiple Brain Metastases: A Planning Study on Treatment Concepts

    SciTech Connect (OSTI)

    Prokic, Vesna, E-mail: vesna.prokic@uniklinik-freiburg.de [Department of Radiation Oncology, University Medical Center Freiburg, Freiburg (Germany)] [Department of Radiation Oncology, University Medical Center Freiburg, Freiburg (Germany); Wiedenmann, Nicole; Fels, Franziska; Schmucker, Marianne [Department of Radiation Oncology, University Medical Center Freiburg, Freiburg (Germany)] [Department of Radiation Oncology, University Medical Center Freiburg, Freiburg (Germany); Nieder, Carsten [Department of Oncology and Palliative Medicine, Nordland Hospital, Bodo (Norway) [Department of Oncology and Palliative Medicine, Nordland Hospital, Bodo (Norway); Institute of Clinical Medicine, Faculty of Health Sciences, University of Tromso, Tromso (Norway); Grosu, Anca-Ligia [Department of Radiation Oncology, University Medical Center Freiburg, Freiburg (Germany)] [Department of Radiation Oncology, University Medical Center Freiburg, Freiburg (Germany)

    2013-01-01T23:59:59.000Z

    Purpose: To develop a new treatment planning strategy in patients with multiple brain metastases. The goal was to perform whole brain irradiation (WBI) with hippocampal sparing and dose escalation on multiple brain metastases. Two treatment concepts were investigated: simultaneously integrated boost (SIB) and WBI followed by stereotactic fractionated radiation therapy sequential concept (SC). Methods and Materials: Treatment plans for both concepts were calculated for 10 patients with 2-8 brain metastases using volumetric modulated arc therapy. In the SIB concept, the prescribed dose was 30 Gy in 12 fractions to the whole brain and 51 Gy in 12 fractions to individual brain metastases. In the SC concept, the prescription was 30 Gy in 12 fractions to the whole brain followed by 18 Gy in 2 fractions to brain metastases. All plans were optimized for dose coverage of whole brain and lesions, simultaneously minimizing dose to the hippocampus. The treatment plans were evaluated on target coverage, homogeneity, and minimal dose to the hippocampus and organs at risk. Results: The SIB concept enabled more successful sparing of the hippocampus; the mean dose to the hippocampus was 7.55 {+-} 0.62 Gy and 6.29 {+-} 0.62 Gy, respectively, when 5-mm and 10-mm avoidance regions around the hippocampus were used, normalized to 2-Gy fractions. In the SC concept, the mean dose to hippocampus was 9.8 {+-} 1.75 Gy. The mean dose to the whole brain (excluding metastases) was 33.2 {+-} 0.7 Gy and 32.7 {+-} 0.96 Gy, respectively, in the SIB concept, for 5-mm and 10-mm hippocampus avoidance regions, and 37.23 {+-} 1.42 Gy in SC. Conclusions: Both concepts, SIB and SC, were able to achieve adequate whole brain coverage and radiosurgery-equivalent dose distributions to individual brain metastases. The SIB technique achieved better sparing of the hippocampus, especially when a10-mm hippocampal avoidance region was used.

  10. Regulation of brain copper homeostasis by the brain barrier systems: Effects of Fe-overload and Fe-deficiency

    SciTech Connect (OSTI)

    Monnot, Andrew D.; Behl, Mamta; Ho, Sanna; Zheng, Wei, E-mail: wzheng@purdue.edu

    2011-11-15T23:59:59.000Z

    Maintaining brain Cu homeostasis is vital for normal brain function. The role of systemic Fe deficiency (FeD) or overload (FeO) due to metabolic diseases or environmental insults in Cu homeostasis in the cerebrospinal fluid (CSF) and brain tissues remains unknown. This study was designed to investigate how blood-brain barrier (BBB) and blood-SCF barrier (BCB) regulated Cu transport and how FeO or FeD altered brain Cu homeostasis. Rats received an Fe-enriched or Fe-depleted diet for 4 weeks. FeD and FeO treatment resulted in a significant increase (+ 55%) and decrease (- 56%) in CSF Cu levels (p < 0.05), respectively; however, neither treatment had any effect on CSF Fe levels. The FeD, but not FeO, led to significant increases in Cu levels in brain parenchyma and the choroid plexus. In situ brain perfusion studies demonstrated that the rate of Cu transport into the brain parenchyma was significantly faster in FeD rats (+ 92%) and significantly slower (- 53%) in FeO rats than in controls. In vitro two chamber Transwell transepithelial transport studies using primary choroidal epithelial cells revealed a predominant efflux of Cu from the CSF to blood compartment by the BCB. Further ventriculo-cisternal perfusion studies showed that Cu clearance by the choroid plexus in FeD animals was significantly greater than control (p < 0.05). Taken together, our results demonstrate that both the BBB and BCB contribute to maintain a stable Cu homeostasis in the brain and CSF. Cu appears to enter the brain primarily via the BBB and is subsequently removed from the CSF by the BCB. FeD has a more profound effect on brain Cu levels than FeO. FeD increases Cu transport at the brain barriers and prompts Cu overload in the CNS. The BCB plays a key role in removing the excess Cu from the CSF.

  11. Solar Brain Srl | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov YouKizildere IRaghuraji Agro Industries Pvt LtdShawangunk, New York:SiG26588°,SocorromercurySolaire DirectBrain Srl Jump

  12. Visualizing Brain Metals in Health and Disease

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What'sis Taking Over OurThe Iron SpinPrincetonUsing Maps1 -Visualizing Brain Metals in Health and Disease

  13. Brain Receptor Structures Key to Future Therapeutics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041clothAdvanced Materials Advanced Materials Find FindRewindParticleBorncelebrates itsBradyBrain

  14. Brain Receptor Structures Key to Future Therapeutics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625govInstrumentstdmadapInactiveVisiting the TWPSuccess Stories Site MapSolarAboutTaubman BradburyBradleyBrain

  15. Mobile Multimedia Sensor Networks: Architecture and Routing

    E-Print Network [OSTI]

    Chen, Min

    Mobile Multimedia Sensor Networks: Architecture and Routing 1Min Chen, 2 Mohsen Guizani, 3 Minho Jo technology and multimedia systems have exhibited a strong potential and tendency on improving human life by enabling smart services in ubiquitous computing environments. This paper investigates a mobile multimedia

  16. Ultra-wideband radar sensors and networks

    DOE Patents [OSTI]

    Leach, Jr., Richard R; Nekoogar, Faranak; Haugen, Peter C

    2013-08-06T23:59:59.000Z

    Ultra wideband radar motion sensors strategically placed in an area of interest communicate with a wireless ad hoc network to provide remote area surveillance. Swept range impulse radar and a heart and respiration monitor combined with the motion sensor further improves discrimination.

  17. High Performance Network Monitoring

    SciTech Connect (OSTI)

    Martinez, Jesse E [Los Alamos National Laboratory

    2012-08-10T23:59:59.000Z

    Network Monitoring requires a substantial use of data and error analysis to overcome issues with clusters. Zenoss and Splunk help to monitor system log messages that are reporting issues about the clusters to monitoring services. Infiniband infrastructure on a number of clusters upgraded to ibmon2. ibmon2 requires different filters to report errors to system administrators. Focus for this summer is to: (1) Implement ibmon2 filters on monitoring boxes to report system errors to system administrators using Zenoss and Splunk; (2) Modify and improve scripts for monitoring and administrative usage; (3) Learn more about networks including services and maintenance for high performance computing systems; and (4) Gain a life experience working with professionals under real world situations. Filters were created to account for clusters running ibmon2 v1.0.0-1 10 Filters currently implemented for ibmon2 using Python. Filters look for threshold of port counters. Over certain counts, filters report errors to on-call system administrators and modifies grid to show local host with issue.

  18. Connecting to the Internet Securely; Protecting Home Networks CIAC-2324

    SciTech Connect (OSTI)

    Orvis, W J; Krystosek, P; Smith, J

    2002-11-27T23:59:59.000Z

    With more and more people working at home and connecting to company networks via the Internet, the risk to company networks to intrusion and theft of sensitive information is growing. Working from home has many positive advantages for both the home worker and the company they work for. However, as companies encourage people to work from home, they need to start considering the interaction of the employee's home network and the company network he connects to. This paper discusses problems and solutions related to protection of home computers from attacks on those computers via the network connection. It does not consider protection of those systems from people who have physical access to the computers nor does it consider company laptops taken on-the-road. Home networks are often targeted by intruders because they are plentiful and they are usually not well secured. While companies have departments of professionals to maintain and secure their networks, home networks are maintained by the employee who may be less knowledgeable about network security matters. The biggest problems with home networks are that: Home networks are not designed to be secure and may use technologies (wireless) that are not secure; The operating systems are not secured when they are installed; The operating systems and applications are not maintained (for security considerations) after they are installed; and The networks are often used for other activities that put them at risk for being compromised. Home networks that are going to be connected to company networks need to be cooperatively secured by the employee and the company so they do not open up the company network to intruders. Securing home networks involves many of the same operations as securing a company network: Patch and maintain systems; Securely configure systems; Eliminate unneeded services; Protect remote logins; Use good passwords; Use current antivirus software; and Moderate your Internet usage habits. Most of these items do not take a lot of work, but require an awareness of the risks involved in not doing them or doing them incorrectly. The security of home networks and communications with company networks can be significantly improved by adding an appropriate software or hardware firewall to the home network and using a protected protocol such as Secure Sockets Layer (SSL), a Virtual Private Network (VPN), or Secure Shell (SSH) for connecting to the company network.

  19. Incidence of Leukoencephalopathy After Whole-Brain Radiation Therapy for Brain Metastases

    SciTech Connect (OSTI)

    Ebi, Junko, E-mail: junkoe@fmu.ac.jp [Department of Radiology, Fukushima Medical University, Fukushima (Japan)] [Department of Radiology, Fukushima Medical University, Fukushima (Japan); Sato, Hisashi; Nakajima, Masaru; Shishido, Fumio [Department of Radiology, Fukushima Medical University, Fukushima (Japan)] [Department of Radiology, Fukushima Medical University, Fukushima (Japan)

    2013-04-01T23:59:59.000Z

    Purpose: To evaluate the incidence of leukoencephalopathy after whole-brain radiation therapy (WBRT) in patients with brain metastases. Methods and Materials: We retrospectively reviewed 111 patients who underwent WBRT for brain metastases from April 2001 through March 2008 and had evaluable computed tomography (CT) and/or magnetic resonance imaging (MRI) at least 1 month after completion of WBRT. We evaluated the leukoencephalopathy according to the Common Terminology Criteria for Adverse Events, version 3.0. The patients who had brain tumor recurrence after WBRT were censored at the last follow-up CT or MRI without recurrence. To evaluate the risk factors for leukoencephalopathy, bivariate analysis was performed using a logistic regression analysis adjusted for follow-up time. Factors included in the analysis were age, gender, dose fractionation, 5-fluorouracil, methotrexate, cisplatin, and other chemotherapeutic agents. Results: The median age of the 111 patients was 60.0 years (range, 23-89 years). The median follow-up was 3.8 months (range, 1.0-38.1 months). Leukoencephalopathy developed in 23 of the 111 patients. Grades 1, 2, and 3 were observed in 8, 7, and 8 patients, respectively. The incidence was 34.4% (11 of 32), 42.9% (6 of 14), 66.7% (2 of 3), and 100% (2 of 2) of the patients who were followed up for ?6, ?12, ?24, and ?36 months, respectively. In the bivariate analysis, older age (?65 years) was significantly correlated with higher risk of leukoencephalopathy (odds ratio 3.31; 95% confidence interval 1.15-9.50; P=.03). Conclusions: The incidence of leukoencephalopathy after WBRT was 34.4% with ?6 months follow-up, and increased with longer follow-up. Older age was a significant risk factor. The schedule of WBRT for patients with brain metastases should be carefully determined, especially for favorable patients.

  20. antibodies mediate improved: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of antibody must be carefully considered before the use of streptavidin clearance. D. Marshall; R. B. Pedley; J. A. Boden; R. Boden; R. H. J. Begent 26 PASSIVE ALLERGISATION OF...