National Library of Energy BETA

Sample records for il tx mi

  1. Harnessing the power of Deep Learning :sromanka@tx.technion.ac.il Roman Kaplan

    E-Print Network [OSTI]

    Cidon, Israel

    " Harnessing the power of Deep Learning :sromanka@tx.technion.ac.il Roman Kaplan The hottest topic the exact application 2. We think how to implement the right system. 3. We (mostly you) chooseReduce, Hadoop/Spark/GraphLab. Use Machine Learning for Your Desired Purpose :sromanka@tx.technion.ac.il Roman

  2. Table 2 -Lime use and practices on Corn, major producing states, 2001 CO GA IL IN IA KS KY MI MN MO NE NY NC ND OH PA SD TX WI Area

    E-Print Network [OSTI]

    Kammen, Daniel M.

    MO NE NY NC ND OH PA SD TX WI Area Lime applied NR 85 81 85 67 16 72 55 27 65 10 57 53 NR 70 95 3 1 50 51 Lime (tons treated acre) NR 1.0 2.1 1.9 2.5 2.1 2.4 2.0 2.6 2.8 1.5 1.9 1.1 NR 1.9 1.7 NR 0.5 2 NC ND OH PA SD TX WI Area Lime applied NR 95 90 69 18 69 71 14 77 16 76 99 NR 82 80 NR 5 58 54 Lime

  3. Mi piacciono i colori, ma non proprio tutti. Mi piace il bianco del sole sulla faccia quando sto a occhi chiusi nel cortile. Il verde

    E-Print Network [OSTI]

    Frosini, Patrizio

    ridevano, sbirciando a tratti il tipo coi crisantemi. Un riso nero e sguaiato. Uno di loro mimava il mazzo

  4. Arsenite evokes IL-6 secretion, autocrine regulation of STAT3 signaling, and miR-21 expression, processes involved in the EMT and malignant transformation of human bronchial epithelial cells

    SciTech Connect (OSTI)

    Luo, Fei; Xu, Yuan; Ling, Min; Zhao, Yue; Xu, Wenchao; Liang, Xiao; Jiang, Rongrong; Wang, Bairu; Bian, Qian; Liu, Qizhan

    2013-11-15

    Arsenite is an established human carcinogen, and arsenite-induced inflammation contributes to malignant transformation of cells, but the molecular mechanisms by which cancers are produced remain to be established. The present results showed that, evoked by arsenite, secretion of interleukin-6 (IL-6), a pro-inflammatory cytokine, led to the activation of STAT3, a transcription activator, and to increased levels of a microRNA, miR-21. Blocking IL-6 with anti-IL-6 antibody and inhibiting STAT3 activation reduced miR-21 expression. For human bronchial epithelial cells, cultured in the presence of anti-IL-6 antibody for 3 days, the arsenite-induced EMT and malignant transformation were reversed. Thus, IL-6, acting on STAT3 signaling, which up-regulates miR-21in an autocrine manner, contributes to the EMT induced by arsenite. These data define a link from inflammation to EMT in the arsenite-induced malignant transformation of HBE cells. This link, mediated through miRNAs, establishes a mechanism for arsenite-induced lung carcinogenesis. - Highlights: • Arsenite evokes IL-6 secretion. • IL-6 autocrine mediates STAT3 signaling and up-regulates miR-21expression. • Inflammation is involved in arsenite-induced EMT.

  5. , : roym@ee.technion.ac.il -OpenStack

    E-Print Network [OSTI]

    Cidon, Israel

    (OVS) . , , . OpenFlow. #12; OpenFlow and SDN Emulating Data-Centers by MiniNet : yanivbi@tx.technion.ac.il ( Data , . Topology Verification in OpenFlow datacenter networks : yanivbi@tx.technion.ac.il Datacenter. , mininet datacenter , " . -datacenter , Openflow. 2

  6. EIS-0412: TX Energy, LLC, Industrial Gasification Facility Near...

    Office of Environmental Management (EM)

    2: TX Energy, LLC, Industrial Gasification Facility Near Beaumont, TX EIS-0412: TX Energy, LLC, Industrial Gasification Facility Near Beaumont, TX February 18, 2009 EIS-0412:...

  7. NONPROFIT ORG DETROIT, MI

    E-Print Network [OSTI]

    Berdichevsky, Victor

    NONPROFIT ORG US POSTAGE PAID DETROIT, MI PERMIT NO 3844 College of Engineering Wayne State University 5050 Anthony Wayne Drive Room 1153 · Detroit, MI 48202 Phone (313) 577-3780 · Fax (313) 577, Wayne State University 5050 Anthony Wayne Drive Detroit, MI 48202 My first assignment for Ex

  8. LADY BIRD JOHNSON MIDDLE SCHOOL IRVING, TX

    E-Print Network [OSTI]

    and purge ports. #12;LADY BIRD JOHNSON MIDDLE SCHOOL IRVING, TX 3' x 5' Solar Panels 191 watts per panel 600 KW Solar Array 2,988 Solar Panels 850,000 kWh Annual Output Solar Classroom Deck SOLAR PV SYSTEM #12 in the United States #12;LADY BIRD JOHNSON MIDDLE SCHOOL IRVING, TX THE LAYOUT AFTER HOURS GYM ENTRY SOLAR

  9. Tank 241-TX-111 tank characterization plan

    SciTech Connect (OSTI)

    Homi, C.S., Westinghouse Hanford

    1996-05-09

    This document is a plan that identifies the information needed to address relevant issues concerning short-term and long-term storage and long-term management of single-shell tank 241-TX-111.

  10. Tank 241-TX-105 tank characterization plan

    SciTech Connect (OSTI)

    Homi, C.S., Westinghouse Hanford

    1996-05-09

    This document is a plan that identifies the information needed to address relevant issues concerning short-term and long-term storage and long-term management of single-shell tank 241-TX-105.

  11. TX-100 manufacturing final project report.

    SciTech Connect (OSTI)

    Ashwill, Thomas D.; Berry, Derek S.

    2007-11-01

    This report details the work completed under the TX-100 blade manufacturing portion of the Carbon-Hybrid Blade Developments: Standard and Twist-Coupled Prototype project. The TX-100 blade is a 9 meter prototype blade designed with bend-twist coupling to augment the mitigation of peak loads during normal turbine operation. This structural coupling was achieved by locating off axis carbon fiber in the outboard portion of the blade skins. The report will present the tooling selection, blade production, blade instrumentation, blade shipping and adapter plate design and fabrication. The baseline blade used for this project was the ERS-100 (Revision D) wind turbine blade. The molds used for the production of the TX-100 were originally built for the production of the CX-100 blade. The same high pressure and low pressure skin molds were used to manufacture the TX-100 skins. In order to compensate for the difference in skin thickness between the CX-100 and the TX-100, however, a new TX-100 shear web plug and mold were required. Both the blade assembly fixture and the root stud insertion fixture used for the CX-100 blades could be utilized for the TX-100 blades. A production run of seven TX-100 prototype blades was undertaken at TPI Composites during the month of October, 2004. Of those seven blades, four were instrumented with strain gauges before final assembly. After production at the TPI Composites facility in Rhode Island, the blades were shipped to various test sites: two blades to the National Wind Technology Center at the National Renewable Energy Laboratory in Boulder, Colorado, two blades to Sandia National Laboratory in Albuquerque, New Mexico and three blades to the United States Department of Agriculture turbine field test facility in Bushland, Texas. An adapter plate was designed to allow the TX-100 blades to be installed on existing Micon 65/13M turbines at the USDA site. The conclusion of this program is the kick-off of the TX-100 blade testing at the three testing facilities.

  12. The TX Fonts December 15, 2000

    E-Print Network [OSTI]

    Mintmire, John W.

    The TX Fonts Young Ryu December 15, 2000 Contents 1 Introduction 2 2 Changes 2 3 A Problem: DVIPS, 2000) 1st public release 2.0 (November 2, 2000) · An encoding error in txi and txbi (`$' "24) is fixed. (Not all TS1 encoding glyphs are implemented.) 2.1 (November 18, 2000) · Complete implementation of TS1

  13. ,"Alamo, TX Natural Gas Pipeline Imports From Mexico (MMcf)"

    U.S. Energy Information Administration (EIA) Indexed Site

    Alamo, TX Natural Gas Pipeline Imports From Mexico (MMcf)" ,"Click worksheet name or tab at bottom for data" ,"Worksheet Name","Description"," Of Series","Frequency","Latest Data...

  14. Hanford Single Shell Tank Leak Causes and Locations - 241-TX Farm

    SciTech Connect (OSTI)

    Girardot, C. L.; Harlow, D> G.

    2014-07-22

    This document identifies 241-TX Tank Farm (TX Farm) leak causes and locations for the 100 series leaking tanks (241-TX-107 and 241-TX-114) identified in RPP-RPT-50870, Rev. 0, Hanford 241-TX Farm Leak Inventory Assessment Report. This document satisfies the TX Farm portion of the target (T04) in the Hanford Federal Facility Agreement and Consent Order milestone M-045-91F.

  15. Real-time sub-<mi>Å>ngstrom...

    Office of Scientific and Technical Information (OSTI)

    Real-time sub-<mi>>ngstrom imaging of reversible and irreversible conformations in rhodium catalysts and graphene Kisielowski, Christian; Wang,...

  16. Freeport, TX Liquefied Natural Gas Exports to Mexico (Million...

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    Mexico (Million Cubic Feet) Freeport, TX Liquefied Natural Gas Exports to Mexico (Million Cubic Feet) Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2013 2,725 - No Data...

  17. Tank 241-TX-116 tank characterization plan. Revision 1

    SciTech Connect (OSTI)

    Homi, C.S.

    1996-05-10

    This document is a plan that identifies the information needed to address relevant issues concerning short-term and long-term storage and long-term management of single-shell tank 241-TX-116.

  18. Package `MiST' July 2, 2014

    E-Print Network [OSTI]

    Brent, Roger

    Package `MiST' July 2, 2014 Type Package Title Mixed effects Score Test for continuous outcomes topics documented: MiST-package 10 1 #12;2 linear.test MiST-package Mixed effects Score Test Description Test for association between

  19. miRNAs in brain development

    SciTech Connect (OSTI)

    Petri, Rebecca; Malmevik, Josephine; Fasching, Liana; Åkerblom, Malin; Jakobsson, Johan

    2014-02-01

    MicroRNAs (miRNAs) are small, non-coding RNAs that negatively regulate gene expression at the post-transcriptional level. In the brain, a large number of miRNAs are expressed and there is a growing body of evidence demonstrating that miRNAs are essential for brain development and neuronal function. Conditional knockout studies of the core components in the miRNA biogenesis pathway, such as Dicer and DGCR8, have demonstrated a crucial role for miRNAs during the development of the central nervous system. Furthermore, mice deleted for specific miRNAs and miRNA-clusters demonstrate diverse functional roles for different miRNAs during the development of different brain structures. miRNAs have been proposed to regulate cellular functions such as differentiation, proliferation and fate-determination of neural progenitors. In this review we summarise the findings from recent studies that highlight the importance of miRNAs in brain development with a focus on the mouse model. We also discuss the technical limitations of current miRNA studies that still limit our understanding of this family of non-coding RNAs and propose the use of novel and refined technologies that are needed in order to fully determine the impact of specific miRNAs in brain development. - Highlights: • miRNAs are essential for brain development and neuronal function. • KO of Dicer is embryonically lethal. • Conditional Dicer KO results in defective proliferation or increased apoptosis. • KO of individual miRNAs or miRNA families is necessary to determine function.

  20. Prot. 413 / Visto il R

    E-Print Network [OSTI]

    Di Pillo, Gianni

    bibli l'art. 13 del ONE PER IL L'UNIVERSIT IMENTO DI R "TEATRO N ROCEDURA C ribuzioni de D. R. n. 135

  1. Rubbiatron, il reattore da Nobel

    E-Print Network [OSTI]

    Cappon, M

    1998-01-01

    Produrr\\Â {a} 30 volte l'energia immessa, ma in modo pulito e sicuro: \\Â {e} la centrale nucleare del prossimo millenio, secondo il progretto revoluzionario di Carlo Rubbia.

  2. Characterization of interleukin-15 (IL-15) and the IL-15 receptor complex

    SciTech Connect (OSTI)

    Kennedy, M.K.; Park, L.S.

    1996-05-01

    IL-15 interacts with a heterotrimeric receptor that consists of the {beta} and {gamma} subunits of the IL-2 receptor (IL-2R) as well as a specific, high-affinity IL-15-binding subunit, which is designated IL-15R{alpha}. Since both the {beta} and the {gamma} subunits of the IL-2R are required for signaling by either IL-2 or IL-15, it is not surprising that these cytokines share many activities in vitro. However, the differential expression of these cytokines and the {alpha} chains of their receptors within various tissues and cell types suggests that IL-2 and IL-15 may perform at least partially distinct physiological functions. The production of IL-15 by macrophages, and possibly other cell types, in response to environmental stimuli and infectious agents suggests that IL-15 may play a role in protective immune responses, allograft rejection, and the pathogenesis of autoimmune diseases. 56 refs.

  3. MI high power operation and future plans

    SciTech Connect (OSTI)

    Kourbanis, Ioanis; /Fermilab

    2008-09-01

    Fermilab's Main Injector on acceleration cycles to 120 GeV has been running a mixed mode operation delivering beam to both the antiproton source for pbar production and to the NuMI[1] target for neutrino production since 2005. On January 2008 the slip stacking process used to increase the beam to the pbar target was expanded to include the beam to the NuMI target increasing both the beam intensity and power. The current high power MI operation will be described along with the near future plans.

  4. txH20: Volume 7, Number 1 (Complete) 

    E-Print Network [OSTI]

    Wythe, Kathy

    2011-01-01

    of working with a top-notch communications team. ?is special drought issue of txH?O is evidence of its good work. Neal Wilkins Working to make every drop count Published by Texas Water Resources Institute Editor Kathy Wythe Texas Water Resources... ] Timeline of Droughts in TexasD The United States signs a water treaty with Mexico for allocation of the waters of the Rio Grande below Fort Quitman, Texas. 1940 1941 1942 1943 1944 1945 1946 1947 1948...

  5. Rotary mode core sampling approved checklist: 241-TX-113

    SciTech Connect (OSTI)

    Fowler, K.D.

    1998-08-03

    The safety assessment for rotary mode core sampling was developed using certain bounding assumptions, however, those assumptions were not verified for each of the existing or potential flammable gas tanks. Therefore, a Flammable Gas/Rotary Mode Core Sampling Approved Checklist has been completed for tank 241-TX-113 prior to sampling operations. This transmittal documents the dispositions of the checklist items from the safety assessment.

  6. Rotary mode core sampling approved checklist: 241-TX-116

    SciTech Connect (OSTI)

    FOWLER, K.D.

    1999-02-24

    The safety assessment for rotary mode core sampling was developed using certain bounding assumptions, however, those assumptions were not verified for each of the existing or potential flammable gas tanks. Therefore, a Flammable Gas/Rotary Mode Core Sampling Approved Checklist has been completed for tank 241-TX-116 prior to sampling operations. This transmittal documents the dispositions of the checklist items from the safety assessment.

  7. EIS-0412: TX Energy, LLC, Industrial Gasification Facility Near Beaumont,

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of5Department oftoStatementMitigationTX | Department of

  8. AVETE PROGETTI PER IL FUTURO?

    E-Print Network [OSTI]

    De Cindio, Fiorella

    areas of technology: · Biological and biomimetic materials; · Polymers and polymer science; · ElectronicAVETE PROGETTI PER IL FUTURO? Science and Technology ReSeaRch on advanced maTeRialS #12;BANDI 2009. To underline the recent scientific and technological progress made, people talk increasingly often of knowledge

  9. The NuMI Neutrino Beam

    E-Print Network [OSTI]

    P. Adamson; K. Anderson; M. Andrews; R. Andrews; I. Anghel; D. Augustine; A. Aurisano; S. Avvakumov; D. S. Ayres; B. Baller; B. Barish; G. Barr; W. L. Barrett; R. H. Bernstein; J. Biggs; M. Bishai; A. Blake; V. Bocean; G. J. Bock; D. J. Boehnlein; D. Bogert; K. Bourkland; S. V. Cao; C. M. Castromonte; S. Childress; B. C. Choudhary; J. A. B. Coelho; J. H. Cobb; L. Corwin; D. Crane; J. P. Cravens; D. Cronin-Hennessy; R. J. Ducar; J. K. de Jong; A. V. Devan; N. E. Devenish; M. V. Diwan; A. R. Erwin; C. O. Escobar; J. J. Evans; E. Falk; G. J. Feldman; T. H. Fields; R. Ford; M. V. Frohne; H. R. Gallagher; V. Garkusha; R. A. Gomes; M. C. Goodman; P. Gouffon; N. Graf; R. Gran; N. Grossman; K. Grzelak; A. Habig; S. R. Hahn; D. Harding; D. Harris; P. G. Harris; J. Hartnell; R. Hatcher; S. Hays; K. Heller; A. Holin; J. Huang; J. Hylen; A. Ibrahim; D. Indurthy; G. M. Irwin; Z. Isvan; D. E. Jaffe; C. James; D. Jensen; J. Johnstone; T. Kafka; S. M. S. Kasahara; G. Koizumi; S. Kopp; M. Kordosky; A. Kreymer; K. Lang; C. Laughton; G. Lefeuvre; J. Ling; P. J. Litchfield; L. Loiacono; P. Lucas; W. A. Mann; A. Marchionni; M. L. Marshak; N. Mayer; C. McGivern; M. M. Medeiros; R. Mehdiyev; J. R. Meier; M. D. Messier; D. G. Michael; R. H. Milburn; J. L. Miller; W. H. Miller; S. R. Mishra; S. Moed Sher; C. D. Moore; J. Morfin; L. Mualem; S. Mufson; S. Murgia; M. Murtagh; J. Musser; D. Naples; J. K. Nelson; H. B. Newman; R. J. Nichol; J. A. Nowak; J. O Connor; W. P. Oliver; M. Olsen; M. Orchanian; S. Osprey; R. B. Pahlka; J. Paley; A. Para; R. B. Patterson; T. Patzak; Z. Pavlovic; G. Pawloski; A. Perch; E. A. Peterson; D. A. Petyt; M. M. Pfutzner; S. Phan-Budd; R. K. Plunkett; N. Poonthottathil; P. Prieto; D. Pushka; X. Qiu; A. Radovic; R. A. Rameika; J. Ratchford; B. Rebel; R. Reilly; C. Rosenfeld; H. A. Rubin; K. Ruddick; M. C. Sanchez; N. Saoulidou; L. Sauer; J. Schneps; D. Schoo; A. Schreckenberger; P. Schreiner; P. Shanahan; R. Sharma; W. Smart; C. Smith; A. Sousa; A. Stefanik; N. Tagg; R. L. Talaga; G. Tassotto; J. Thomas; J. Thompson; M. A. Thomson; X. Tian; A. Timmons; D. Tinsley; S. C. Tognini; R. Toner; D. Torretta; I. Trostin; G. Tzanakos; J. Urheim; P. Vahle; K. Vaziri; E. Villegas; B. Viren; G. Vogel; R. C. Webber; A. Weber; R. C. Webb; A. Wehmann; C. White; L. Whitehead; L. H. Whitehead; S. G. Wojcicki; M. L. Wong-Squires; T. Yang; F. X. Yumiceva; V. Zarucheisky; R. Zwaska

    2015-07-29

    This paper describes the hardware and operations of the Neutrinos at the Main Injector (NuMI) beam at Fermilab. It elaborates on the design considerations for the beam as a whole and for individual elements. The most important design details of individual components are described. Beam monitoring systems and procedures, including the tuning and alignment of the beam and NuMI long-term performance, are also discussed.

  10. The NuMI Neutrino Beam

    E-Print Network [OSTI]

    Adamson, P; Andrews, M; Andrews, R; Anghel, I; Augustine, D; Aurisano, A; Avvakumov, S; Ayres, D S; Baller, B; Barish, B; Barr, G; Barrett, W L; Bernstein, R H; Biggs, J; Bishai, M; Blake, A; Bocean, V; Bock, G J; Boehnlein, D J; Bogert, D; Bourkland, K; Cao, S V; Castromonte, C M; Childress, S; Choudhary, B C; Coelho, J A B; Cobb, J H; Corwin, L; Crane, D; Cravens, J P; Cronin-Hennessy, D; Ducar, R J; de Jong, J K; Devan, A V; Devenish, N E; Diwan, M V; Erwin, A R; Escobar, C O; Evans, J J; Falk, E; Feldman, G J; Fields, T H; Ford, R; Frohne, M V; Gallagher, H R; Garkusha, V; Gomes, R A; Goodman, M C; Gouffon, P; Graf, N; Gran, R; Grossman, N; Grzelak, K; Habig, A; Hahn, S R; Harding, D; Harris, D; Harris, P G; Hartnell, J; Hatcher, R; Hays, S; Heller, K; Holin, A; Huang, J; Hylen, J; Ibrahim, A; Indurthy, D; Irwin, G M; Isvan, Z; Jaffe, D E; James, C; Jensen, D; Johnstone, J; Kafka, T; Kasahara, S M S; Koizumi, G; Kopp, S; Kordosky, M; Kreymer, A; Lang, K; Laughton, C; Lefeuvre, G; Ling, J; Litchfield, P J; Loiacono, L; Lucas, P; Mann, W A; Marchionni, A; Marshak, M L; Mayer, N; McGivern, C; Medeiros, M M; Mehdiyev, R; Meier, J R; Messier, M D; Michael, D G; Milburn, R H; Miller, J L; Miller, W H; Mishra, S R; Sher, S Moed; Moore, C D; Morfin, J; Mualem, L; Mufson, S; Murgia, S; Murtagh, M; Musser, J; Naples, D; Nelson, J K; Newman, H B; Nichol, R J; Nowak, J A; Connor, J O; Oliver, W P; Olsen, M; Orchanian, M; Osprey, S; Pahlka, R B; Paley, J; Para, A; Patterson, R B; Patzak, T; Pavlovic, Z; Pawloski, G; Perch, A; Peterson, E A; Petyt, D A; Pfutzner, M; Phan-Budd, S; Plunkett, R K; Poonthottathil, N; Prieto, P; Pushka, D; Qiu, X; Radovic, A; Rameika, R A; Ratchford, J; Rebel, B; Reilly, R; Rosenfeld, C; Rubin, H A; Ruddick, K; Sanchez, M C; Saoulidou, N; Sauer, L; Schneps, J; Schoo, D; Schreckenberger, A; Schreiner, P; Shanahan, P; Sharma, R; Smart, W; Smith, C; Sousa, A; Stefanik, A; Tagg, N; Talaga, R L; Tassotto, G; Thomas, J; Thompson, J; Thomson, M A; Tian, X; Timmons, A; Tinsley, D; Tognini, S C; Toner, R; Torretta, D; Trostin, I; Tzanakos, G; Urheim, J; Vahle, P; Vaziri, K; Villegas, E; Viren, B; Vogel, G; Webber, R C; Weber, A; Webb, R C; Wehmann, A; White, C; Whitehead, L; Whitehead, L H; Wojcicki, S G; Wong-Squires, M L; Yang, T; Yumiceva, F X; Zarucheisky, V; Zwaska, R

    2015-01-01

    This paper describes the hardware and operations of the Neutrinos at the Main Injector (NuMI) beam at Fermilab. It elaborates on the design considerations for the beam as a whole and for individual elements. The most important design details of individual components are described. Beam monitoring systems and procedures, including the tuning and alignment of the beam and NuMI long-term performance, are also discussed.

  11. The NuMI Neutrino Beam

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Adamson, P.; Anderson, K.; Andrews, M.; Andrews, R.; Anghel, I.; Augustine, D.; Aurisano, A.; Avvakumov, S.; Ayres, D. S.; Baller, B.; et al

    2015-10-20

    Our paper describes the hardware and operations of the Neutrinos at the Main Injector (NuMI) beam at Fermilab. It elaborates on the design considerations for the beam as a whole and for individual elements. The most important part of our design details pertaining to individual components is described. Beam monitoring systems and procedures, including the tuning and alignment of the beam and NuMI long-term performance, are also discussed.

  12. Equazioni contro il cancro a comunit scientifica

    E-Print Network [OSTI]

    Bellomo, Nicola

    descrivere fenomeni di grande interesse legati a specifiche te- rapie. A esempio, una collabo- razione tra il

  13. Il pumping lemma Proprieta' di chiusura

    E-Print Network [OSTI]

    Rossi, Francesca

    Il pumping lemma Proprieta' di chiusura Proprieta' di decisione Proprieta' dei linguaggi regolari Proprieta' dei linguaggi regolari #12;Il pumping lemma Proprieta' di chiusura Proprieta' di decisione Proprieta' dei Linguaggi regolari Pumping Lemma. Ogni linguaggio regolare soddisfa il pumping lemma. Se

  14. Structural and Biophysical Studies of the Human IL-7/IL-7R[alpha] Complex

    SciTech Connect (OSTI)

    McElroy, Craig A.; Dohm, Julie A.; Walsh, Scott T.R.; (OSU); (UPENN)

    2009-03-06

    IL-7 and IL-7R{alpha} bind the {gamma}{sub c} receptor, forming a complex crucial to several signaling cascades leading to the development and homeostasis of T and B cells. We report that the IL-7R{alpha} ectodomain uses glycosylation to modulate its binding constants to IL-7, unlike the other receptors in the {gamma}{sub c} family. IL-7 binds glycosylated IL-7R{alpha} 300-fold more tightly than unglycosylated IL-7R{alpha}, and the enhanced affinity is attributed primarily to an accelerated on rate. Structural comparison of IL-7 in complex to both forms of IL-7R{alpha} reveals that glycosylation does not participate directly in the binding interface. The SCID mutations of IL-7R{alpha} locate outside the binding interface with IL-7, suggesting that the expressed mutations cause protein folding defects in IL-7R{alpha}. The IL-7/IL-7R{alpha} structures provide a window into the molecular recognition events of the IL-7 signaling cascade and provide sites to target for designing new therapeutics to treat IL-7-related diseases.

  15. IL

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouth DakotaRobbins and MyersHr. Anthony V. Andolina:I * .z-y:c* -7f:; /

  16. MI Gap Clearing Kicker Magnet Design Review

    SciTech Connect (OSTI)

    Jensen, Chris; /Fermilab

    2008-10-01

    The kicker system requirements were originally conceived for the NOvA project. NOvA is a neutrino experiment located in Minnesota. To achieve the desired neutrino flux several upgrades are required to the accelerator complex. The Recycler will be used as a proton pre-injector for the Main Injector (MI). As the Recycler is the same size as the MI, it is possible to do a single turn fill ({approx}11 {micro}sec), minimizing the proton injection time in the MI cycle and maximizing the protons on target. The Recycler can then be filled with beam while the MI is ramping to extract beam to the target. To do this requires two new transfer lines. The existing Recycler injection line was designed for 10{pi} pbar beams, not the 20{pi} proton beams we anticipate from the Booster. The existing Recycler extraction line allows for proton injection through the MI, while we want direct injection from the Booster. These two lines will be decommissioned. The new injection line from the MI8 line into the Recycler will start at 848 and end with injection kickers at RR104. The new extraction line in the RR30 straight section will start with a new extraction kicker at RR232 and end with new MI injection kickers at MI308. Finally, to reduce beam loss activation in the enclosure, a new gap clearing kicker will be used to extract uncaptured beam created during the slip stack injection process down the existing dump line. It was suggested that the MI could benefit from this type of system immediately. This led to the early installation of the gap clearing system in the MI, followed by moving the system to Recycler during NOvA. The specifications also changed during this process. Initially the rise and fall time requirements were 38 ns and the field stability was {+-}1%. The 38 ns is based on having a gap of 2 RF buckets between injections. (There are 84 RF buckets that can be filled from the Booster for each injection, but 82 would be filled with beam. MI and Recycler contain 588 RF buckets.) A rough cost/benefit analysis showed that increasing the number of empty buckets to 3 decreased the kicker system cost by {approx}30%. This could be done while not extending the running time since this is only a 1% reduction in protons per pulse, hence the rise and fall time are now 57 ns. Additionally, the {+-}1% tolerance would have required a fast correction kicker while {+-}3% could be achieved without this kicker. The loosened tolerance was based on experience on wide band damping systems in the MI. A higher power wideband damping system is a better use of the resources as it can be used to correct for multiple sources of emittance growth. Finally, with the use of this system for MI instead of Recycler, the required strength grew from 1.2 mrad to 1.7 mrad. The final requirements for this kicker are listed.

  17. txH2O: Volume 5, Number 3 (Complete) 

    E-Print Network [OSTI]

    Texas Water Resources Institute

    2010-01-01

    is funded in part by the U.S. Geological Survey and authorized by the Water Resources Research Act. To subscribe to txH2O or New Waves, TWRI?s monthly e-mail newsletter, visit http://twri.tamu.edu. 2 I This is your stream. This is your stream on drugs... and understood by ECLOX-using personnel, after the completion of this year?s cities? protocols, that will be 36 cities that have the tools to maintain secure drinking water.? *Some information from a TEEX news release A big production is under- way in Texas...

  18. RAPID/Roadmap/1-TX-a | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page onRAPID/Geothermal/Exploration/Colorado <RAPID/Geothermal/Water Use/Nevada <UtahMontanasource HistoryNM-aTX-a <

  19. RAPID/Roadmap/11-TX-a | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page onRAPID/Geothermal/Exploration/Colorado <RAPID/Geothermal/Water Use/Nevada <UtahMontanasourceWA-a <aaTX-a <

  20. RAPID/Roadmap/11-TX-b | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page onRAPID/Geothermal/Exploration/Colorado <RAPID/Geothermal/Water Use/Nevada <UtahMontanasourceWA-a <aaTX-a <b

  1. RAPID/Roadmap/11-TX-c | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page onRAPID/Geothermal/Exploration/Colorado <RAPID/Geothermal/Water Use/Nevada <UtahMontanasourceWA-a <aaTX-a <bc

  2. RAPID/Roadmap/12-TX-a | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page onRAPID/Geothermal/Exploration/Colorado <RAPID/Geothermal/Water Use/Nevada <UtahMontanasourceWA-aCA-aMT-aTX-a <

  3. RAPID/Roadmap/4-TX-a | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page onRAPID/Geothermal/Exploration/Colorado <RAPID/Geothermal/Water Use/Nevadaa < RAPID‎f <CA-aabTX-a < RAPID‎

  4. ARM - Field Campaign - TX-2002 AIRS Validation Campaign

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach HomeA Better Anode DesigngovCampaignsSpring Single Column Model IOP ARMStructure02.09govCampaignsTX-2002

  5. RAPID/Roadmap/13-TX-a | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION JEnvironmental Jump to:EA EIS Report UrlNM-b < RAPID‎ | Roadmap JumpNV-a < RAPID‎ |TX-a

  6. S/w Quality Assurance CAST-TX 1 Software Quality Assurance

    E-Print Network [OSTI]

    Tian, Jeff

    Management Nov. 30, 2002 Prof. Jeff Tian, SMU #12;S/w Quality Assurance CAST-TX 2 Software Quality: Why: customer view of quality Probability: statistical modeling Time/input/environment: OP · OP: OperationalS/w Quality Assurance CAST-TX 1 Software Quality Assurance -- Meeting New Challenges Jeff Tian

  7. Nomenclature Issues and the Y-Chromosome J.M. Butler (Genetic Genealogy Conference, Houston, TX)

    E-Print Network [OSTI]

    Nomenclature Issues and the Y-Chromosome J.M. Butler (Genetic Genealogy Conference, Houston, TX on Genetic Genealogy Houston, TX October 20, 2007 http://www.ybase.org/convert.asp The Problem · STR marker in the forensic DNA community? · What are some potential solutions to aid the genetic genealogy community

  8. US ENC IL Site Consumption

    Gasoline and Diesel Fuel Update (EIA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustments (Billion Cubic Feet) Wyoming963 1.969 1.979Coal Consumers inYear JanSales Type: Sales AlabamaPanelIL

  9. Sequence determinants of pri-miRNA processing

    E-Print Network [OSTI]

    Auyeung, Vincent C. (Vincent Churk-man)

    2012-01-01

    MicroRNAs (miRNAs) are short RNAs that regulate many processes in physiology and pathology by guiding the repression of target messenger RNAs. For classification purposes, miRNAs are defined as ~22 nt RNAs that are produced ...

  10. miR-132 and miR-212 are increased in pancreatic cancer and target the retinoblastoma tumor suppressor

    SciTech Connect (OSTI)

    Park, Jong-Kook [College of Pharmacy, Ohio State University, Columbus, OH 43210 (United States)] [College of Pharmacy, Ohio State University, Columbus, OH 43210 (United States); Henry, Jon C. [Department of Surgery, Ohio State University, Columbus, OH 43210 (United States)] [Department of Surgery, Ohio State University, Columbus, OH 43210 (United States); Jiang, Jinmai [College of Pharmacy, Ohio State University, Columbus, OH 43210 (United States)] [College of Pharmacy, Ohio State University, Columbus, OH 43210 (United States); Esau, Christine [Regulus Therapeutics, Carlsbad, CA (United States)] [Regulus Therapeutics, Carlsbad, CA (United States); Gusev, Yuriy [Lombardi Cancer Center, Georgetown University, Washington, DC (United States)] [Lombardi Cancer Center, Georgetown University, Washington, DC (United States); Lerner, Megan R. [Veterans Affairs Medical Center, Oklahoma City, OK (United States)] [Veterans Affairs Medical Center, Oklahoma City, OK (United States); Postier, Russell G. [Department of Surgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK (United States)] [Department of Surgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK (United States); Brackett, Daniel J. [Veterans Affairs Medical Center, Oklahoma City, OK (United States)] [Veterans Affairs Medical Center, Oklahoma City, OK (United States); Schmittgen, Thomas D., E-mail: Schmittgen.2@osu.edu [College of Pharmacy, Ohio State University, Columbus, OH 43210 (United States)

    2011-03-25

    Research highlights: {yields} The expression of miR-132 and miR-212 are significantly increased in pancreatic cancer. {yields} miR-132 and miR-212 target the tumor suppressor pRb, resulting in enhanced proliferation. {yields} miR-132 and miR-212 expression is increased by a {beta}2 adrenergic receptor agonist, suggesting a novel mechanism for pancreatic cancer progression. -- Abstract: Numerous microRNAs (miRNAs) are reported as differentially expressed in cancer, however the consequence of miRNA deregulation in cancer is unknown for many miRNAs. We report that two miRNAs located on chromosome 17p13, miR-132 and miR-212, are over-expressed in pancreatic adenocarcinoma (PDAC) tissues. Both miRNAs are predicted to target the retinoblastoma tumor suppressor, Rb1. Validation of this interaction was confirmed by luciferase reporter assay and western blot in a pancreatic cancer cell line transfected with pre-miR-212 and pre-miR-132 oligos. Cell proliferation was enhanced in Panc-1 cells transfected with pre-miR-132/-212 oligos. Conversely, antisense oligos to miR-132/-212 reduced cell proliferation and caused a G{sub 2}/M cell cycle arrest. The mRNA of a number of E2F transcriptional targets were increased in cells over expressing miR-132/-212. Exposing Panc-1 cells to the {beta}2 adrenergic receptor agonist, terbutaline, increased the miR-132 and miR-212 expression by 2- to 4-fold. We report that over-expression of miR-132 and miR-212 result in reduced pRb protein in pancreatic cancer cells and that the increase in cell proliferation from over-expression of these miRNAs is likely due to increased expression of several E2F target genes. The {beta}2 adrenergic pathway may play an important role in this novel mechanism.

  11. “Nodal Gap” Induced by the Incommensurate Diagonal Spin Density Modulation in Underdoped High- <mi>Tmi>c> Superconductors

    SciTech Connect (OSTI)

    Zhou, Tao [Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China; Gao, Yi [Nanjing Normal University, Nanjing 210023, China; Zhu, Jian-Xin [Los Alamos National Laboratory, Los Alamos, NM 87545, USA

    2015-01-01

    Recently it was revealed that the whole Fermi surface is fully gapped for several families of underdoped cuprates. The existence of the finite energy gap along the<mi>d>-wave nodal lines (nodal gap) contrasts the common understanding of the<mi>d>-wave pairing symmetry, which challenges the present theories for the high-<mi>Tmi><mi>c>superconductors. Here we propose that the incommensurate diagonal spin-density-wave order can account for the above experimental observation. The Fermi surface and the local density of states are also studied. Our results are in good agreement with many important experiments in high-<mi>Tmi><mi>c>superconductors.

  12. CX-100 and TX-100 blade field tests.

    SciTech Connect (OSTI)

    Holman, Adam (USDA-Agriculture Research Service, Bushland, TX); Jones, Perry L.; Zayas, Jose R.

    2005-12-01

    In support of the DOE Low Wind Speed Turbine (LWST) program two of the three Micon 65/13M wind turbines at the USDA Agricultural Research Service (ARS) center in Bushland, Texas will be used to test two sets of experimental blades, the CX-100 and TX-100. The blade aerodynamic and structural characterization, meteorological inflow and wind turbine structural response will be monitored with an array of 75 instruments: 33 to characterize the blades, 15 to characterize the inflow, and 27 to characterize the time-varying state of the turbine. For both tests, data will be sampled at a rate of 30 Hz using the ATLAS II (Accurate GPS Time-Linked Data Acquisition System) data acquisition system. The system features a time-synchronized continuous data stream and telemetered data from the turbine rotor. This paper documents the instruments and infrastructure that have been developed to monitor these blades, turbines and inflow.

  13. SMART GRID: IL RUOLO DELLA REGOLAZIONE

    E-Print Network [OSTI]

    SMART GRID: IL RUOLO DELLA REGOLAZIONE Luca Lo Schiavo Autorità per l'energia elettrica e il gas; storage, idrogeno, etc. ­ Nuove applicazioni elettriche (es. veicoli elettrici) ­ Fiscalità · Quadro & system management a livello micro · Diffusione veicoli elettrici · Scenario plausibile con prezzi CO2

  14. Liver fibrosis causes downregulation of miRNA-150 and miRNA-194 in hepatic stellate cells, and their overexpression causes decreased stellate cell activation.

    E-Print Network [OSTI]

    Wu, Jian; Zern, M A

    2010-01-01

    Liver ?brosis causes downregulation of miRNA-150 and miRNA-and their overexpression causes decreased stellate cellJ, Zern MA. Liver ?brosis causes downregulation of miRNA-150

  15. Verification of the WRF model during a high ozone event over Houston, TX 

    E-Print Network [OSTI]

    Ames, Douglas Seeley

    2003-01-01

    High ozone values were observed in Houston, TX during August 25 - September 1, 2000. A comparison of WRF data with observations and MM5 data was conducted to determine the WRF model's performance in simulating the meteorological conditions...

  16. Francesco Cangiullo e il "suo" Teatro della Sorpresa (1921)

    E-Print Network [OSTI]

    Musella, Mario

    2012-01-01

    le quali “[i]l maggior nemico del riso è l’emozione . . .naturale. ” Henri Bergson, Il Riso. Saggio sul significatoma soprattutto si è molto riso ed il pubblico ha dovuto

  17. Analytical Study of Hexapod miRNAs using Phylogenetic Methods

    E-Print Network [OSTI]

    Mishra, A K

    2012-01-01

    MicroRNAs (miRNAs) are a class of non-coding RNAs that regulate gene expression. Identification of total number of miRNAs even in completely sequenced organisms is still an open problem. However, researchers have been using techniques that can predict limited number of miRNA in an organism. In this paper, we have used homology based approach for comparative analysis of miRNA of hexapoda group .We have used Apis mellifera, Bombyx mori, Anopholes gambiae and Drosophila melanogaster miRNA datasets from miRBase repository. We have done pair wise as well as multiple alignments for the available miRNAs in the repository to identify and analyse conserved regions among related species. Unfortunately, to the best of our knowledge, miRNA related literature does not provide in depth analysis of hexapods. We have made an attempt to derive the commonality among the miRNAs and to identify the conserved regions which are still not available in miRNA repositories. The results are good approximation with a small number of mis...

  18. BMPs Regulate the Oft Development via miRNAs 

    E-Print Network [OSTI]

    Bai, Yan

    2014-08-04

    c-Jun N-terminal Kinase LAP Latency Associated Peptide LLC Large Latent Complex LTBP Latent Tgf-? Binding Protein MFS Marfan Syndrome mi...

  19. ,"Detroit, MI Natural Gas Pipeline Imports From Canada (MMcf...

    U.S. Energy Information Administration (EIA) Indexed Site

    ,"Worksheet Name","Description"," Of Series","Frequency","Latest Data for" ,"Data 1","Detroit, MI Natural Gas Pipeline Imports From Canada (MMcf)",1,"Annual",2014 ,"Release...

  20. The Sequential Action of miR156 and miR172 Regulates Developmental Timing

    E-Print Network [OSTI]

    Weigel, Detlef

    Planck Institute for Developmental Biology, D-72076 Tu¨ bingen, Germany *Correspondence: spoethig@sas elegans (Moss, 2007; Rougvie, 2005) and plants (Ba¨ urle and Dean, 2006; Chuck and Hake, 2005; Poethig in Moss, 2007; Pasquinelli and Ruvkun, 2002; Rougvie, 2005). These were the first miRNAs to be discovered

  1. RCRA Assessment Plan for Single-Shell Tank Waste Management Area TX-TY

    SciTech Connect (OSTI)

    Horton, Duane G.

    2007-03-26

    WMA TX-TY contains underground, single-shell tanks that were used to store liquid waste that contained chemicals and radionuclides. Most of the liquid has been removed, and the remaining waste is regulated under the RCRA as modi¬fied in 40 CFR Part 265, Subpart F and Washington State’s Hazardous Waste Management Act . WMA TX-TY was placed in assessment monitoring in 1993 because of elevated specific conductance. A groundwater quality assessment plan was written in 1993 describing the monitoring activities to be used in deciding whether WMA TX-TY had affected groundwater. That plan was updated in 2001 for continued RCRA groundwater quality assessment as required by 40 CFR 265.93 (d)(7). This document further updates the assessment plan for WMA TX-TY by including (1) information obtained from ten new wells installed at the WMA after 1999 and (2) information from routine quarterly groundwater monitoring during the last five years. Also, this plan describes activities for continuing the groundwater assessment at WMA TX TY.

  2. Members of the miRNA-200 Family Regulate Olfactory Neurogenesis

    E-Print Network [OSTI]

    Choi, Philip S.

    MicroRNAs (miRNAs) are highly expressed in vertebrate neural tissues, but the contribution of specific miRNAs to the development and function of different neuronal populations is still largely unknown. We report that miRNAs ...

  3. Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells

    SciTech Connect (OSTI)

    Vrba, Lukas; Jensen, Taylor J.; Garbe, James C.; Heimark, Ronald L.; Cress, Anne E.; Dickinson, Sally; Stampfer, Martha R.; Futscher, Bernard W.

    2009-12-23

    BACKGROUND: The microRNA-200 family participates in the maintenance of an epithelial phenotype and loss of its expression can result in epithelial to mesenchymal transition (EMT). Furthermore, the loss of expression of miR-200 family members is linked to an aggressive cancer phenotype. Regulation of the miR-200 family expression in normal and cancer cells is not fully understood. METHODOLOGY/ PRINCIPAL FINDINGS: Epigenetic mechanisms participate in the control of miR-200c and miR-141 expression in both normal and cancer cells. A CpG island near the predicted mir-200c/mir-141 transcription start site shows a striking correlation between miR-200c and miR-141 expression and DNA methylation in both normal and cancer cells, as determined by MassARRAY technology. The CpG island is unmethylated in human miR-200/miR-141 expressing epithelial cells and in miR-200c/miR-141 positive tumor cells. The CpG island is heavily methylated in human miR-200c/miR-141 negative fibroblasts and miR-200c/miR-141 negative tumor cells. Mouse cells show a similar inverse correlation between DNA methylation and miR-200c expression. Enrichment of permissive histone modifications, H3 acetylation and H3K4 trimethylation, is seen in normal miR-200c/miR-141-positive epithelial cells, as determined by chromatin immunoprecipitation coupled to real-time PCR. In contrast, repressive H3K9 dimethylation marks are present in normal miR-200c/miR-141-negative fibroblasts and miR-200c/miR-141 negative cancer cells and the permissive histone modifications are absent. The epigenetic modifier drug, 5-aza-2'-deoxycytidine, reactivates miR-200c/miR-141 expression showing that epigenetic mechanisms play a functional role in their transcriptional control. CONCLUSIONS/ SIGNIFICANCE: We report that DNA methylation plays a role in the normal cell type-specific expression of miR-200c and miR-141 and this role appears evolutionarily conserved, since similar results were obtained in mouse. Aberrant DNA methylation of the miR-200c/141 CpG island is closely linked to their inappropriate silencing in cancer cells. Since the miR-200c cluster plays a significant role in EMT, our results suggest an important role for DNA methylation in the control of phenotypic conversions in normal cells.

  4. IL DIRETTORE Visto il Regolamento per il reclutamento di Ricercatori con contratto a tempo Determinato emanato con D.R.

    E-Print Network [OSTI]

    Di Pillo, Gianni

    Regione Lazio Viste le Delibere del Consiglio del Dipartimento di Fisiologia e Farmacologia "Vittorio ottobre 2010; VISTA la delibera del Consiglio di Dipartimento di Fisiologia e Farmacologia "Vittorio", settore scientifico disciplinare BIO/09, presso il Dipartimento di Fisiologia e Farmacologia "Vittorio

  5. Curcumin blocks interleukin (IL)-2 signaling in T-lymphocytes by inhibiting IL-2 synthesis, CD25 expression, and IL-2 receptor signaling

    SciTech Connect (OSTI)

    Forward, Nicholas A.; Conrad, David M.; Power Coombs, Melanie R.; Doucette, Carolyn D.; Furlong, Suzanne J.; Lin, Tong-Jun; Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia ; Hoskin, David W.

    2011-04-22

    Highlights: {yields} Curcumin inhibits CD4{sup +} T-lymphocyte proliferation. {yields} Curcumin inhibits interleukin-2 (IL-2) synthesis and CD25 expression by CD4{sup +} T-lymphocytes. {yields} Curcumin interferes with IL-2 receptor signaling by inhibiting JAK3 and STAT5 phosphorylation. {yields} IL-2-dependent regulatory T-lymphocyte function and Foxp3 expression is downregulated by curcumin. -- Abstract: Curcumin (diferulomethane) is the principal curcuminoid in the spice tumeric and a potent inhibitor of activation-induced T-lymphocyte proliferation; however, the molecular basis of this immunosuppressive effect has not been well studied. Here we show that micromolar concentrations of curcumin inhibited DNA synthesis by mouse CD4{sup +} T-lymphocytes, as well as interleukin-2 (IL-2) and CD25 ({alpha} chain of the high affinity IL-2 receptor) expression in response to antibody-mediated cross-linking of CD3 and CD28. Curcumin acted downstream of protein kinase C activation and intracellular Ca{sup 2+} release to inhibit I{kappa}B phosphorylation, which is required for nuclear translocation of the transcription factor NF{kappa}B. In addition, IL-2-dependent DNA synthesis by mouse CTLL-2 cells, but not constitutive CD25 expression, was impaired in the presence of curcumin, which demonstrated an inhibitory effect on IL-2 receptor (IL-2R) signaling. IL-2-induced phosphorylation of STAT5A and JAK3, but not JAK1, was diminished in the presence of curcumin, indicating inhibition of critical proximal events in IL-2R signaling. In line with the inhibitory action of curcumin on IL-2R signaling, pretreatment of CD4{sup +}CD25{sup +} regulatory T-cells with curcumin downregulated suppressor function, as well as forkhead box p3 (Foxp3) expression. We conclude that curcumin inhibits IL-2 signaling by reducing available IL-2 and high affinity IL-2R, as well as interfering with IL-2R signaling.

  6. Wood River Levee Reconstruction, Madison County, IL

    E-Print Network [OSTI]

    US Army Corps of Engineers

    Wood River Levee Reconstruction, Madison County, IL 25 October 2006 Abstract: The recommended plan provides for flood damage reduction and restores the original degree of protection of the Wood River Levee-federal sponsor is the Wood River Drainage and Levee District. The Wood River Levee System was authorized

  7. miR-92a family and their target genes in tumorigenesis and metastasis

    SciTech Connect (OSTI)

    Li, Molin; Guan, Xingfang; Sun, Yuqiang; Mi, Jun; Shu, Xiaohong; Liu, Fang; Li, Chuangang

    2014-04-15

    The miR-92a family, including miR-25, miR-92a-1, miR-92a-2 and miR-363, arises from three different paralog clusters miR-17-92, miR-106a-363, and miR-106b-25 that are highly conservative in the process of evolution, and it was thought as a group of microRNAs (miRNAs) correlated with endothelial cells. Aberrant expression of miR-92a family was detected in multiple cancers, and the disturbance of miR-92a family was related with tumorigenesis and tumor development. In this review, the progress on the relationship between miR-92a family and their target genes and malignant tumors will be summarized. - Highlights: • Aberrant expression of miR-92a, miR-25 and miR-363 can be observed in many kinds of malignant tumors. • The expression of miR-92a family is regulated by LOH, epigenetic alteration, transcriptional factors such as SP1, MYC, E2F, wild-type p53 etc. • Roles of miR-92a family in tumorigenesis and development: promoting cell proliferation, invasion and metastasis, inhibiting cell apoptosis.

  8. Texas Tech University, Lubbock, TX, 2010 Table 1 2009 Texas Research Incentive Program Funding

    E-Print Network [OSTI]

    Rock, Chris

    #12;© Texas Tech University, Lubbock, TX, 2010 #12;7 9 19 22 29 32 39 42 47 51 56 57 67 71 74 80 82 The Once-in-a-Lifetime Opportunity Conceptualizing a New Vision and Mission Environmental (SWOT) Analysis Acknowledgements Strategic Planning Council Texas Tech Administration #12;Guy Bailey President Texas Tech

  9. April 11, 2001 Presentation at BRC, Temple, TX. Hydrological Applications of

    E-Print Network [OSTI]

    . Introduction · AVHRR - Advanced Very High Resolution Radiometer · It is a sensor aboard NOAA - POES. · AVHRR Presentation at BRC, Temple, TX. Potential Evapo-Transpiration · Energy Balance Model Rn = E + H + G Where: Rn2/208 (Grass Reference), u2 = wind velocity(m.s-1), Ta = air temperature (ºC), Ts = land surface

  10. Optimal Deployment Plan of Emission Reduction Technologies for TxDOT's Construction Equipment 

    E-Print Network [OSTI]

    Bari, Muhammad Ehsanul

    2010-10-12

    -road equipment of TxDOT to reduce emissions in a cost effective and optimal manner. Three technologies were considered for deployment in this research, (1) hydrogen enrichment (HE), (2) selective catalytic reduction (SCR) and (3) fuel additive (FA... Gas ....................................................................... 24 Biodiesel ............................................................................ 24 Hydrogen...

  11. ACM SIGGRAPH 2002, San Antonio, TX Modeling the Accumulation of Wind-Driven Snow

    E-Print Network [OSTI]

    O'Brien, James F.

    ACM SIGGRAPH 2002, San Antonio, TX Modeling the Accumulation of Wind-Driven Snow Technical Sketch of snow drifts formed by the accumulation of wind-blown snow near buildings and other obstacles. Our our method is able to model how the snow is convected, deposited, and lifted by the wind. The results

  12. miR-143 Interferes with ERK5 Signaling, and Abrogates Prostate Cancer Progression in Mice

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    miR-143 Interferes with ERK5 Signaling, and Abrogates Prostate Cancer Progression in Mice Cyrielle-regulated kinase-5 (ERK5) activity. We show here that ERK5 is a miR-143 target in prostate cancer. Conclusions: mi, Apparailly F, Fernandez PL, et al. (2009) miR-143 Interferes with ERK5 Signaling, and Abrogates Prostate

  13. NuMI Target Station AHIPA09 10/19/09

    E-Print Network [OSTI]

    McDonald, Kirk

    MI Target Station AHIPA09 10/19/09 Jim Hylen/FNAL Page 11Remote 5-axis lift table Numi target+baffle on liftNuMI Target Station AHIPA09 10/19/09 Jim Hylen/FNAL Page 1 Target Station Infrastructure: The Nu slide overview of NuMI #12;NuMI Target Station AHIPA09 10/19/09 Jim Hylen/FNAL Page 2 NuMI produces

  14. Regulation of Synaptic Structure and Function by FMRP-Associated MicroRNAs miR-125b and miR-132

    E-Print Network [OSTI]

    Edbauer, Dieter

    MicroRNAs (miRNAs) are noncoding RNAs that suppress translation of specific mRNAs. The miRNA machinery interacts with fragile X mental retardation protein (FMRP), which functions as translational repressor. We show that ...

  15. Opportunities Suspended: The Disparate Impact of Disciplinary Exclusion from School

    E-Print Network [OSTI]

    Losen, Daniel J.; Gillespie, Jonathan

    2012-01-01

    SD 299 TX Alief Island MI Detroit City School District GASD 299 TX Alief Island MI Detroit City School District GA

  16. Characterization of atmospheric ammonia near Fort Worth, TX Part II. Impact of ammonia on particulate matter formation

    E-Print Network [OSTI]

    Institute for the Study of Earth, Oceans, and Space, University of New Hampshire, Durham, NH, USA 8 Earth, USA 2 Department of Electrical and Computer Engineering, Rice University, Houston, TX, USA 3 Now

  17. Spectral-efficiency of multi-antenna links in ad-hoc wireless networks with limited Tx CSI

    E-Print Network [OSTI]

    Govindasamy, Siddhartan

    An asymptotic expression is derived for the mean spectral efficiency of multi-antenna links randomly distributed on a plane in a uniform manner where transmitters (Tx) have Channel-State-Information (CSI) of the channels ...

  18. Proceedings of the ASME 2014 Dynamic Systems and Control Conference October 22-24, 2014, San Antonio, TX, USA

    E-Print Network [OSTI]

    Brennan, Sean

    , San Antonio, TX, USA DSCC2014-6274 DIFFERENTIAL DIAGNOSTICS FOR LITHIUM ION BATTERY CELLS CONNECTED This paper presents a new method for estimating the capac- ity of a lithium ion battery cell in the presence

  19. Category:Chicago, IL | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION J APPENDIX ECoopButte County,Camilla, Georgia: Energy014771°,NorthCLEAN Webinar JumpChicago, IL

  20. miRNA-205 affects infiltration and metastasis of breast cancer

    SciTech Connect (OSTI)

    Wang, Zhouquan; Department of Tumor, SenGong Hospital of Shaanxi, Xi’an 710300 ; Liao, Hehe; Deng, Zhiping; Yang, Po; Du, Ning; Zhanng, Yunfeng; Ren, Hong

    2013-11-08

    Highlights: •We detected expression of miR-205 in breast cancer cell lines and tissue samples. •We suggest miR-205 is downregulated in human breast cancer tissues and MCF7 cells. •We suggest the lower expression of miR-205 play a role in breast cancer onset. •These data suggest that miR-205 directly targets HER3 in human breast cancer. -- Abstract: Background: An increasing number of studies have shown that miRNAs are commonly deregulated in human malignancies, but little is known about the function of miRNA-205 (miR-205) in human breast cancer. The present study investigated the influence of miR-205 on breast cancer malignancy. Methods: The expression level of miR-205 in the MCF7 breast cancer cell line was determined by quantitative (q)RT-PCR. We then analyzed the expression of miR-205 in breast cancer and paired non-tumor tissues. Finally, the roles of miR-205 in regulating tumor proliferation, apoptosis, migration, and target gene expression were studied by MTT assay, flow cytometry, qRT-PCR, Western blotting and luciferase assay. Results: miR-205 was downregulated in breast cancer cells or tissues compared with normal breast cell lines or non-tumor tissues. Overexpression of miR-205 reduced the growth and colony-formation capacity of MCF7 cells by inducing apoptosis. Overexpression of miR-205 inhibited MCF7 cell migration and invasiveness. By bioinformation analysis, miR-205 was predicted to bind to the 3? untranslated regions of human epidermal growth factor receptor (HER)3 mRNA, and upregulation of miR-205 reduced HER3 protein expression. Conclusion: miR-205 is a tumor suppressor in human breast cancer by post-transcriptional inhibition of HER3 expression.

  1. miR-132, an experience-dependent microRNA, is essential for visual cortex plasticity

    E-Print Network [OSTI]

    Mellios, Nikolaos

    Using quantitative analyses, we identified microRNAs (miRNAs) that were abundantly expressed in visual cortex and that responded to dark rearing and/or monocular deprivation. The most substantially altered miRNA, miR-132, ...

  2. Molecular Cell Loss of miR-200 Inhibition of Suz12 Leads to

    E-Print Network [OSTI]

    In an inducible oncogenesis model, the miR-200 family is inhibited during CSC formation but not trans- formation

  3. Discovery of miRNA-regulated processes in mammalian development

    E-Print Network [OSTI]

    Young, Amanda Garfinkel

    2010-01-01

    The genomes of plants and animals encode hundreds of non-coding ~22nt RNAs termed "microRNAs" (miRNAs). These RNAs guide the sequence-specific inhibition of translation and destabilization of mRNA targets through short ...

  4. Radiosensitizing Effects of Ectopic miR-101 on Non-Small-Cell Lung Cancer Cells Depend on the Endogenous miR-101 Level

    SciTech Connect (OSTI)

    Chen, Susie; Wang Hongyan; Ng, Wooi Loon; Curran, Walter J.; Wang Ya

    2011-12-01

    Purpose: Previously, we showed that ectopic miR-101 could sensitize human tumor cells to radiation by targeting ATM and DNA-PK catalytic subunit (DNA-PKcs) to inhibit DNA repair, as the endogenous miR-101 levels are low in tumors in general. However, the heterogeneity of human cancers may result in an exception. The purpose of this study was to test the hypothesis that a few tumor cell lines with a high level of endogenous miR-101 would prove less response to ectopic miR-101. Methods and Materials: Fourteeen non-small-cell lung cancer (NSCLC) cell lines and one immortalized non-malignant lung epithelial cell line (NL20) were used for comparing endogenous miR-101 levels by real-time reverse transcription-polymerase chain reaction. Based on the different miR-101 levels, four cell lines with different miR-101 levels were chosen for transfection with a green fluorescent protein-lentiviral plasmid encoding miR-101. The target protein levels were measured by using Western blotting. The radiosensitizing effects of ectopic miR-101 on these NSCLC cell lines were determined by a clonogenic assay and xenograft mouse model. Results: The endogenous miR-101 level was similar or lower in 13 NSCLC cell lines but was 11-fold higher in one cell line (H157) than in NL20 cells. Although ectopic miR-101 efficiently decreased the ATM and DNA-PKcs levels and increased the radiosensitization level in H1299, H1975, and A549 cells, it did not change the levels of the miR-101 targets or radiosensitivity in H157 cells. Similar results were observed in xenograft mice. Conclusions: A small number of NSCLC cell lines could have a high level of endogenous miR-101. The ectopic miR-101 was able to radiosensitize most NSCLC cells, except for the NSCLC cell lines that had a much higher endogenous miR-101 level. These results suggest that when we choose one miRNA as a therapeutic tool, the endogenous level of the miRNA in each tumor should be considered.

  5. Curriculum di ZONCA FULVIO Stampato il 08-01-2010

    E-Print Network [OSTI]

    Zonca, Fulvio

    Curriculum di ZONCA FULVIO Stampato il 08-01-2010 Pagina 1 di 55 11-04-1988Data ass.: 1. SITUAZIONE): Esp. esterna riconosciuta (in anni): CURRICULUM DI: ZONCA FULVIO89250 10-01-1962 Matricola Cognome;Curriculum di ZONCA FULVIO Stampato il 08-01-2010 Pagina 2 di 55 5. ATTIVITA' PROFESSIONALI SCIENZE FISICHE

  6. Case Study: Continuous Commissioning and Energy Management at Alamo Colleges, San Antonio, TX 

    E-Print Network [OSTI]

    Martinez, J. T.

    2014-01-01

    Commissioning® Process Joseph T. Martinez, PCC Carlos Yagua, PE Hiroko Masuda, Juan-Carlos Baltazar, PhD, PE Ahmet Ugursal, PhD Clean Air Through Energy Efficiency (CATEE) Conference, Dallas, Texas. November 18, 2014 ESL-KT-14-11-40 CATEE 2014: Clean Air.... Measurement and Verification 7. Case Study: Alamo Colleges 2 ESL-KT-14-11-40 CATEE 2014: Clean Air Through Efficiency Conference, Dallas, Texas Nov. 18-20 Case Study: Continuous Commissioning® and Energy Management at Alamo Colleges, San Antonio, TX. Joseph...

  7. The environment of deposition of the Dalton Coal (Upper Pennsylvanian), Palo Pinto Co., TX

    E-Print Network [OSTI]

    Lowenstein, Glenn Robert

    1986-01-01

    C. L = 1ff I I I I I I I I I la 3. 75 I I I l l I l 2 7. 9 ~ ~'8 5 8. 5 0 2000 fi 0 500 rn Figure 5. Da1 ton Coa1 i sopach map based on coal thicknesses measured a1ong the outcrop face and in cores. 25 1D in appendi x C...THE ENVIRONMENT OF DEPOSITION OF THE DALTON COAL (UPPER PENNSYI. VANIAN), PALO PINTO CO. , TX. A Thesis by GLENN ROBERT LOWENSTEIN Submitted to the Graduate College of Texas A&M University in partial fulfillment of the requirements for tne...

  8. File:USDA-CE-Production-GIFmaps-TX.pdf | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QAsource History View New Pages RecentTempCampApplicationWorksheet 2011.pdfSD.pdf Jump to: navigation, searchTX.pdf

  9. File:03-TX-f - Lease of Land Trade Lands.pdf | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTIONRobertsdale, AlabamaETEC GmbHFarinello GeothermalFiderisInformation 3-FD-d -Open EnergyTX-f -

  10. File:03-TX-g - Lease of Relinquishment Act Lands.pdf | Open Energy

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTIONRobertsdale, AlabamaETEC GmbHFarinello GeothermalFiderisInformation 3-FD-d -Open EnergyTX-f

  11. BANDO PER IL RECLUTAMENTO DI UN RICERCATORE CON RAPPORTO DI LAVORO A TEMPO DETERMINATO CO FINANZIATO DALLA REGIONE LAZIO PER IL SETTORE S/D

    E-Print Network [OSTI]

    Di Pillo, Gianni

    FINANZIATO DALLA REGIONE LAZIO PER IL SETTORE S/D BIO/09 PRESSO IL DIPARTIMENTO DI FISIOLOGIA E FARMACOLOGIA "VITTORIO ERSPAMER" Il Direttore del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" Visto il Regione Lazio Viste le Delibere del Consiglio del Dipartimento di Fisiologia e Farmacologia "Vittorio

  12. Tank characterization report for single-shell tank 241-TX-104

    SciTech Connect (OSTI)

    FIELD, J.G.

    1999-05-12

    A major function of the Tank Waste Remediation System (TWRS) is to characterize waste in support of waste management and disposal activities at the Hanford Site. Analytical data from sampling and analysis and other available information about a tank are compiled and maintained in a tank characterization report (TCR). This report and its appendices serve as the TCR for single-shell tank 241-TX-104. The objectives of this report are (1) to use characterization data in response to technical issues associated with tank 241-TX-104 waste, and (2) to provide a standard characterization of this waste in terms of a best-basis inventory estimate. Section 2.0 summarizes the response to technical issues, Section 3.0 shows the best-basis inventory estimate, Section 4.0 makes recommendations about the safety status of the tank and additional sampling needs. The appendices contain supporting data and information. This report supports the requirements of the Hanford Federal Facility Agreement and Consent Order (Ecology et al. 1997), Milestone M-44-15c, change request M-44-97-03 to ''issue characterization deliverables consistent with the Waste Information Requirements Document developed for FY 1999'' (Adams et al. 1998).

  13. Tank 241-TX-118, core 236 analytical results for the final report

    SciTech Connect (OSTI)

    ESCH, R.A.

    1998-11-19

    This document is the analytical laboratory report for tank 241-TX-118 push mode core segments collected between April 1, 1998 and April 13, 1998. The segments were subsampled and analyzed in accordance with the Tank 241-TX-118 Push Mode Core sampling and Analysis Plan (TSAP) (Benar, 1997), the Safety Screening Data Quality Objective (DQO) (Dukelow, et al., 1995), the Data Quality Objective to Support Resolution of the Organic Complexant Safety Issue (Organic DQO) (Turner, et al, 1995) and the Historical Model Evaluation Data Requirements (Historical DQO) (Sipson, et al., 1995). The analytical results are included in the data summary table (Table 1). None of the samples submitted for Differential Scanning Calorimetry (DSC) and Total Organic Carbon (TOC) exceeded notification limits as stated in the TSAP (Benar, 1997). One sample exceeded the Total Alpha Activity (AT) analysis notification limit of 38.4{micro}Ci/g (based on a bulk density of 1.6), core 236 segment 1 lower half solids (S98T001524). Appropriate notifications were made. Plutonium 239/240 analysis was requested as a secondary analysis. The statistical results of the 95% confidence interval on the mean calculations are provided by the Tank Waste Remediation Systems Technical Basis Group in accordance with the Memorandum of Understanding (Schreiber, 1997) and are not considered in this report.

  14. IL-11 is a parietal cell cytokine that induces atrophic gastritis

    E-Print Network [OSTI]

    Howlett, Meegan

    Background and Aims IL-is important in gastric damage, mucosal repair and gastric cancer progression. We analysed IL-11 expression in H.pylori infected mouse stomach, the site of gastric IL-11 expression in mice and humans, ...

  15. DOE - Office of Legacy Management -- Chicago North IL Site - IL 05

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouth DakotaRobbins and Myers Co -VANaval ,, *'AliquippaOfficeNorth IL

  16. Intrathymic radioresistant stem cells follow an IL-2/IL-2R pathway during thymic regeneration after sublethal irradiation

    SciTech Connect (OSTI)

    Zuniga-Pfluecker, J.C.K.; Kruisbeek, A.M. )

    1990-05-15

    Sublethally irradiated mice undergo thymic regeneration which follows a phenotypic pattern of events similar to that observed during normal fetal development. Thymic regeneration after irradiation is the product of a limited pool of intrathymic radioresistant stem cells undergoing simultaneous differentiation. We show that in this model of T cell development, thymic regeneration follows a pathway in which the IL-2R is transiently expressed on CD4-/CD8- cells. IL-2R expression occurred during the exponential growth period of thymic regeneration, and IL-2R blocking prevented this explosive growth. Flow cytometry analysis revealed that the IL-2R blockade affected primarily the development of the immature CD3-/CD4-/CD8- (triple negative) cells and their ability to generate CD3+/CD4+/CD8+ or CD3+/CD4+/CD8- and CD3+/CD4-/CD8+ thymocytes. Thus, our findings demonstrate that blocking of the IL-2R resulted in an arrest in proliferation and differentiation by intrathymic radioresistant stem cells, indicating that the IL-2/IL-2R pathway is necessary for the expansion of immature triple negative T cells.

  17. miR-153 and miR-335, Ethanol Sensitive MicroRNAs, Control NSC/NPC Maturation during Fetal Brain Development 

    E-Print Network [OSTI]

    Tsai, Pai Chi

    2014-05-05

    conclude that miR-335 and miR-153 act as molecular brakes to prevent NSCs/NPCs early maturation by regulating cell differentiation genes during the second trimester, and ethanol leads to organizational defects in the developing cerebral cortex through...

  18. EIS-0412: Federal Loan Guarantee to Support Construction of the TX Energy LLC, Industrial Gasification Facility near Beaumont, Texas

    Broader source: Energy.gov [DOE]

    The Department of Energy is assessing the potential environmental impacts for its proposed action of issuing a Federal loan guarantee to TX Energy, LLC (TXE). TXE submitted an application to DOE under the Federal loan guarantee program pursuant to the Energy Policy Act of 2005 (EPAct 2005) to support construction of the TXE industrial Gasification Facility near Beaumont, Texas.

  19. Interleukin-2 (IL-2) dependent expression of biologically relevant IL-2 receptors: uncoupling of anti-T3 induced receptor expression with cyclosporin

    SciTech Connect (OSTI)

    Gitter, A.B.D.; Labus, J.M.; Butler, L.D.

    1986-03-01

    Human peripheral blood T cell expression of IL-2 receptors (IL-2R), detected by both immunocytofluorometry and /sup 125/I-IL-2 binding, was studied using lymphocytes stimulated with monoclonal anti-T3 antibodies (Leu-4, OKT3). Lymphocytes, isolated from healthy individuals, were prescreened and classified as Leu-4 responders or non-responders according to 72 h /sup 3/H-thymidine incorporation experiments. Leu-4 non-responder lymphocytes, though capable of normal IL-2R expression and IL-2 secretion when cultured with OKT3 (IgG2a), expressed little to no IL-2R nor secreted IL-2 when stimulated with Leu-4 (IgG1). In addition, the amount of IL-2 secreted by Leu-4 stimulated, Leu-4 responder cells, was one-third- to one-fifth of that detected when OKT3 was used as the stimulant. The addition of recombinant IL-2 (rIL-2) to a Leu-4 stimulated, Leu-4 non-responder lymphocyte culture, resulted in the expression of IL-2R and cellular proliferation, indicating that IL-2 upregulated its biologically relevant receptor. As expected, cyclosporin-A (CSA) inhibited the secretion of IL-2 and subsequent proliferation of Leu-4 stimulated, Leu-4 responder cells. Unexpectedly, however, the expression of IL-2R was also blocked. Exogenous rIL-2 partially reversed the effect of CSA on IL-2R expression and proliferation. The results indicate that IL-2 may provide an additional, required signal for optimal IL-2R expression.

  20. DLEU2, frequently deleted in malignancy, functions as a critical host gene of the cell cycle inhibitory microRNAs miR-15a and miR-16-1

    SciTech Connect (OSTI)

    Lerner, Mikael; Harada, Masako; Loven, Jakob; Castro, Juan; Davis, Zadie; Oscier, David; Henriksson, Marie; Sangfelt, Olle; Grander, Dan; Corcoran, Martin M.

    2009-10-15

    The microRNAs miR-15a and miR-16-1 are downregulated in multiple tumor types and are frequently deleted in chronic lymphocytic leukemia (CLL), myeloma and mantle cell lymphoma. Despite their abundance in most cells the transcriptional regulation of miR-15a/16-1 remains unclear. Here we demonstrate that the putative tumor suppressor DLEU2 acts as a host gene of these microRNAs. Mature miR-15a/miR-16-1 are produced in a Drosha-dependent process from DLEU2 and binding of the Myc oncoprotein to two alterative DLEU2 promoters represses both the host gene transcript and levels of mature miR-15a/miR-16-1. In line with a functional role for DLEU2 in the expression of the microRNAs, the miR-15a/miR-16-1 locus is retained in four CLL cases that delete both promoters of this gene and expression analysis indicates that this leads to functional loss of mature miR-15a/16-1. We additionally show that DLEU2 negatively regulates the G1 Cyclins E1 and D1 through miR-15a/miR-16-1 and provide evidence that these oncoproteins are subject to miR-15a/miR-16-1-mediated repression under normal conditions. We also demonstrate that DLEU2 overexpression blocks cellular proliferation and inhibits the colony-forming ability of tumor cell lines in a miR-15a/miR-16-1-dependent way. Together the data illuminate how inactivation of DLEU2 promotes cell proliferation and tumor progression through functional loss of miR-15a/miR-16-1.

  1. In questo libretto sono illustrati i quesiti proposti nella seconda edizione del Kangourou dell'Informatica, fase eliminatoria, che si e svolta il 10 marzo 2010. Il software con il quale i quesiti sono stati presentati ai concorrenti

    E-Print Network [OSTI]

    Monga, Mattia

    Kangourou dell'Informatica, fase eliminatoria, che si e svolta il 10 marzo 2010. Il software con il quale i'ambito dell'informatica; vengono anche individuate delle parole chiave che possono essere utili per ricerche promuovere l'informatica come disciplina scienti#12;ca. Violetta Lonati Mattia Monga Anna Morpurgo Lorenzo

  2. Groundwater protection for the NuMI project

    SciTech Connect (OSTI)

    Wehmann, A.; Smart, W.; Menary, S.; Hylen, J.; Childress, S.

    1997-10-01

    The physics requirements for the long base line neutrino oscillation experiment MINOS dictate that the NuMI beamline be located in the aquifer at Fermilab. A methodology is described for calculating the level of radioactivation of groundwater caused by operation of this beamline. A conceptual shielding design for the 750 meter long decay pipe is investigated which would reduce radioactivation of the groundwater to below government standards. More economical shielding designs to meet these requirements are being explored. Also, information on local geology, hydrogeology, government standards, and a glossary have been included.

  3. DOE - Office of Legacy Management -- Star Cutter Corp - MI 15

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouth DakotaRobbins and Myers Co - OHStar Cutter Corp - MI 15 FUSRAP

  4. DOE - Office of Legacy Management -- Westinghouse Naval Ordnance - MI 02

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouth DakotaRobbins and Myers Co -VANaval Ordnance - MI 02 FUSRAP

  5. DOE - Office of Legacy Management -- Wolverine Tube Division - MI 05

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouth DakotaRobbins and Myers Co -VANaval Ordnance - MI

  6. REC Silicon formerly ASiMI | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page onRAPID/Geothermal/Exploration/Colorado <RAPID/Geothermal/Water Use/NevadaaTools < RAPID79.14Silicon formerly ASiMI

  7. MHK Technologies/Mi2 | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION J APPENDIXsource HistoryScenarios Towards 2050Enermar < MHKHydro HelixLangleeMi2 < MHK

  8. La logica e il pensiero visivo 1. Le due funzioni del pensiero visivo

    E-Print Network [OSTI]

    Floridi, Luciano

    retoriche classiche: già nella Institutio Oratoria (XI, iii, 102) Quintiliano attribuiva il computo digitale

  9. Informatica per il Management: Analisi 28/09/2010 Docente: Carla Guerrini 1

    E-Print Network [OSTI]

    Guerrini, Carla

    Informatica per il Management: Analisi Numerica 1 28/09/2010 Docente: Carla Guerrini 1 Informatica per il Management:Informatica per il Management: Analisi NumericaAnalisi Numerica Anno Accademico 2010 possibile e con la massima accuratezza #12;Informatica per il Management: Analisi Numerica 2 28

  10. Il mondo visto da sud e La prima volta. Una conversazione con Franco Cassano

    E-Print Network [OSTI]

    Lollini, Massimo

    2013-01-01

    il pensiero negativo. ” In Albert Camus: Mediterraneo ela rivisitazione di Albert Camus, intellettuale algerino

  11. Hepatitis C Virus Infection and Hepatic Stellate Cell Activation Downregulate miR-29: miR-29 Overexpression Reduces Hepatitis C Viral Abundance in Culture

    E-Print Network [OSTI]

    Bandyopadhyay, Sarmistha

    Background.?Chronic hepatitis C virus (HCV)–induced liver fibrosis involves upregulation of transforming growth factor (TGF)–? and subsequent hepatic stellate cell (HSC) activation. MicroRNAs (miRNAs) regulate HCV infection ...

  12. Global identification of miRNAs and targets in Populus euphratica under salt stress

    E-Print Network [OSTI]

    Deng, Xing-Wang

    Global identification of miRNAs and targets in Populus euphratica under salt stress Bosheng Li, a typical hydro-halophyte, is ideal for studying salt stress responses in woody plants. MicroRNAs (miRNA may regulate tolerance to salt stress but this has not been widely studied in P. euphratica

  13. Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres

    E-Print Network [OSTI]

    Ji, Qing; Hao, Xinbao; Meng, Yang; Zhang, Min; DeSano, Jeffrey; Fan, Daiming; Xu, Liang

    2008-09-21

    Background: MicroRNAs (miRNAs), some of which function as oncogenes or tumor suppressor genes, are involved in carcinogenesis via regulating cell proliferation and/or cell death. MicroRNA miR-34 was recently found to be a direct target of p53...

  14. www.weizmann.ac.il/library Introduction 3

    E-Print Network [OSTI]

    to the Library's printed and digital collections, including books, journals, theses, serials, and online lectures Weizmann Institute of Science Libraries 5 Digital Access · Arranging access to newly purchased electronic#12;www.weizmann.ac.il/library 2 Contents Introduction 3 The Library's Website 3 The Library

  15. IlIill Ills i.iiiii lilt

    E-Print Network [OSTI]

    Handy, Todd C.

    · . .:.. F I, IlIill Ills i.iiiii lilt ``a ``I [. TOWN .,. .., · . THE JOURNAL I 0 F TH E j " ; PLANNJNG INS3DFDUTE : 4, cE - .· ·: .,·., · ? DECEMBER 1926 / VOLV ?40 "/1 I'. CONTENT I TOWN PLANNING THE BRITISH COLUMBIA UNIVERSITY LANDS A GREAT TOWN PLANNING SCHEME FOR WESTERN CANADA; BRIT·IH HOUSIN

  16. Reservoir fracture mapping using microearthquakes: Austin chalk, Giddings field, TX and 76 field, Clinton Co., KY

    SciTech Connect (OSTI)

    Phillips, W.S.; Rutledge, J.T.; Gardner, T.L.; Fairbanks, T.D.; Miller, M.E.; Schuessler, B.K.

    1996-11-01

    Patterns of microearthquakes detected downhole defined fracture orientation and extent in the Austin chalk, Giddings field, TX and the 76 field, Clinton Co., KY. We collected over 480 and 770 microearthquakes during hydraulic stimulation at two sites in the Austin chalk, and over 3200 during primary production in Clinton Co. Data were of high enough quality that 20%, 31% and 53% of the events could be located, respectively. Reflected waves constrained microearthquakes to the stimulated depths at the base of the Austin chalk. In plan view, microearthquakes defined elongate fracture zones extending from the stimulation wells parallel to the regional fracture trend. However, widths of the stimulated zones differed by a factor of five between the two Austin chalk sites, indicating a large difference in the population of ancillary fractures. Post-stimulation production was much higher from the wider zone. At Clinton Co., microearthquakes defined low-angle, reverse-fault fracture zones above and below a producing zone. Associations with depleted production intervals indicated the mapped fractures had been previously drained. Drilling showed that the fractures currently contain brine. The seismic behavior was consistent with poroelastic models that predicted slight increases in compressive stress above and below the drained volume.

  17. Refining: moods and modes for 1984. [From NPRA meeting, San Antonio, TX 3/84

    SciTech Connect (OSTI)

    Not Available

    1984-04-11

    Thousands of refining experts met in March in San Antonio, TX at the 82nd meeting of the National Petroleum Refiners Association, including many international oil-industry officials and executives. For major US refiners, the mood was decidedly optimistic, because: (1) for a number of refiners, negative margins on many crude oils that persisted even after the March 1983 price adjustment by OPEC are finally improving as capacities for upgrading residual fuel into more-valuable light products continue to come onstream; and (2) multinational oil companies, while concerned about downstream market penetration by producing countries, nevertheless expressed the feeling that this would probably further reduce the negotiating power of OPEC. For smaller, nonmajor refiners, the mood was one of concern: in the US, 97 refineries have officially closed since 1981, most of them smaller, inefficient facilities. There was optimism by all about environmental and social concerns, specifically acid rain and lead pollution. For the national oil companies of less-developed countries, a vicious circle emerged concerning the economic ramifications of the continuing development of catalysts for cracking heavy feedstock. This issue presents the fuel price/tax series and industrial fuel prices for March 1984 for countries of the Eastern Hemisphere.

  18. Mi2beta Is Required for c-Globin Gene Silencing: Temporal Assembly of a GATA-1-FOG-1-Mi2 Repressor Complex in b-YAC Transgenic Mice

    E-Print Network [OSTI]

    Costa, Flá via C.; Fedosyuk, Halyna; Chazelle, Allen M.; Neades, Renee Y.; Peterson, Kenneth R.

    2012-12-20

    Mi2b Is Required for c-Globin Gene Silencing: Temporal Assembly of a GATA-1-FOG-1-Mi2 Repressor Complex in b-YAC Transgenic Mice Fla´via C. Costa1¤, Halyna Fedosyuk1, Allen M. Chazelle1, Renee Y. Neades1, Kenneth R. Peterson1,2* 1Department... hemoglobin. A GATA-1-FOG-1-Mi2 repressor complex was recently demonstrated to be recruited to the 2566 GATA motif of the Ac-globin gene. We show that Mi2b is essential for c-globin gene silencing using Mi2b conditional knockout b-YAC transgenic mice...

  19. IL DIRETTORE VISTO l'art. 6 del Regolamento per il reclutamento di Ricercatori con contratto di lavoro a tempo

    E-Print Network [OSTI]

    Di Pillo, Gianni

    .02.2010; VISTA la Convenzione stipulata tra il Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" e la Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" nella seduta del 15.01.2010; VISTA la Delibera Fisiologia e Farmacologia "Vittorio Erspamer" del 19 aprile 2010 nella quale è stata approvata la nomina

  20. miR-128 and its target genes in tumorigenesis and metastasis

    SciTech Connect (OSTI)

    Li, Molin, E-mail: molin_li@hotmail.com [Dalian Medical University, Dalian 116044 (China); Fu, Weiming [Center for Food Safety and Environmental Technology, Guangzhou Institute of Advanced Technology, Chinese Academy of Sciences, Guangzhou 511458 (China); Wo, Lulu; Shu, Xiaohong [Dalian Medical University, Dalian 116044 (China); Liu, Fang [The second affiliated hospital of Dalian Medical University, Dalian 116023 (China); Li, Chuangang, E-mail: li_chuangang@sina.com [The second affiliated hospital of Dalian Medical University, Dalian 116023 (China)

    2013-12-10

    MicroRNAs (miRNAs) are a class of endogenous, non-coding, 18–24 nucleotide length single-strand RNAs that could modulate gene expression at post-transcriptional level. Previous studies have shown that miR-128 enriched in the brain plays an important role in the development of nervous system and the maintenance of normal physical functions. Aberrant expression of miR-128 has been detected in many types of human tumors and its validated target genes are involved in cancer-related biological processes such as cell proliferation, differentiation and apoptosis. In this review, we will summarize the roles of miR-128 and its target genes in tumorigenesis and metastasis. - Highlights: • Aberrant expression of miR-128 can be observed in many kinds of malignant tumors. • The molecular mechanisms regulating miR-128 expression are elucidated. • Roles of miR-128 and its target genes in tumorigenesis and metastasis are summarized.

  1. MiR-150, A Novel and Potent Regulator for MLL-AF9 Leukemic Stem Cells 

    E-Print Network [OSTI]

    Cheruku, Patali

    2013-02-18

    Designing the miR-150 sponge primer set .................................................................. 10 Preparation of the DNA fragment containing the miR-150 sponge sequence ............ 10 Construction of pcDNA5-CMV-d2eGFP-miR150sp... protocol. Enzymatic digestion with XhoI and ApaI confirmed the insertion of the miR-150 sponge fragment. The miR-150sp-eGFP sequence (Figure 1) was then amplified using polymerase chain reaction (PCR) with the BamHI forward and SalI reverse primers, gel...

  2. CORSI DI LAUREA IN INGEGNERIA PER L'AMBIENTE E IL TERRITORIO ED INGEGNERIA CIVILE

    E-Print Network [OSTI]

    Pasquero, Stefano

    CORSI DI LAUREA IN INGEGNERIA PER L'AMBIENTE E IL TERRITORIO ED INGEGNERIA CIVILE Corso di circonferenza. 7) Determinare energia cinetica e energia potenziale di P. L'energia si conserva? Confrontare il

  3. Tassocenosi a Ditteri Chironomidi in fiumi mediterranei (Cilento, Sud Italia): ecologia e implicazioni per il biomonitoraggio

    E-Print Network [OSTI]

    Armanini, David G

    con i parametri abiotici rilevati. Il primo asse rappresenta un gradiente di qualità ed è correlato tassocenosi di riffle e di pool sono risultate significativamente diverse. Il secondo asse rappresenta un

  4. Changes in Native Aquatic Vegetation, Associated Fish Assemblages, and Food Habits of Largemouth Bass (Micropterus salmoides) Following the Addition of Triploid Grass Carp to Manage Hydrilla (Hydrilla Verticillata) in Lake Conroe, TX 

    E-Print Network [OSTI]

    Ireland, Patrick Alexander

    2011-10-21

    Nuisance aquatic vegetation (mainly Hydrilla Verticillata ) has become problematic in Lake Conroe, TX. Consequently, triploid grass carp (Ctenopharynogodon idella) were stocked at densities sufficient to completely denude ...

  5. Prot. n. 1063/2014 SELEZIONE PER IL CONFERIMENTO DI N. 1 BORSA DI STUDIO

    E-Print Network [OSTI]

    interesse per gli studi di risposta sismica locale. Il candidato risponde con competenza riguardo a teoria e

  6. IL-3 and Oncogenic Abl Regulate the Myeloblast Transcriptome by Alt= Stability

    E-Print Network [OSTI]

    Ernst, Jason

    The growth factor interleukin-3 (IL-3) promotes the survival and growth of multipotent hematopoietic progenitors and

  7. AROF Disposizione n. 4343 del 29.10.2014 IL DIRETTORE DELL'AREA

    E-Print Network [OSTI]

    Di Pillo, Gianni

    presso il Servizio POP'S a partire dal 01.11.2014; #12;DISPONE Art. 1 - Sono approvati gli atti relativi occasionale da attivare presso il Servizio POP'S; Art. 2 ­ Viene approvata la seguente graduatoria di meritoAROF Disposizione n. 4343 del 29.10.2014 IL DIRETTORE DELL'AREA VISTO l'art. 7, comma 6 del D

  8. Start S Morgan St End 1933 W Polk St, Chicago, IL 60612

    E-Print Network [OSTI]

    Spirtes, Peter

    Start S Morgan St End 1933 W Polk St, Chicago, IL 60612 When 10/5/11 after 7:00pm Duration 11 mins total Loading... ©2011 Google - Map data ©2011 Google, Sanborn - S Morgan St to 1933 W Polk St, Chicago stops) Polk & Wolcott Walk to 1933 W Polk St, Chicago, IL 60612 About 1 min 1933 W Polk St, Chicago, IL

  9. Computer-Generated Papercutting Jie Xu1 Craig S. Kaplan1 Xiaofeng Mi2

    E-Print Network [OSTI]

    Waterloo, University of

    Computer-Generated Papercutting Jie Xu1 Craig S. Kaplan1 Xiaofeng Mi2 1Computer Graphics Lab David Pattern #12;Related Work Kaplan and Salesin, TOG 2004 Kaplan, GI 2005 #12;Geometric Patterns Geometric

  10. Modulation of Ago-miRNA regulatory networks by cis-sequence elements and target competition

    E-Print Network [OSTI]

    Bosson, Andrew D. (Andrew David)

    2014-01-01

    regulators of gene expression in a wide range of organisms and biological processes. Each miRNA guides Argonaute (Ago) protein complexes to target and repress hundreds of genes in a sequence-dependent manner. To identify ...

  11. Simulations of neutron multiplicity measurements with MCNP-PoliMi.

    SciTech Connect (OSTI)

    Mattingly, John K.; Pozzi, Sara A. (University of Michigan); Clarke, Shaun D. (University of Michigan); Dennis, Ben D. (University of Michigan); Miller, Eric C.

    2010-09-01

    The heightened focus on nuclear safeguards and accountability has increased the need to develop and verify simulation tools for modeling these applications. The ability to accurately simulate safeguards techniques, such as neutron multiplicity counting, aids in the design and development of future systems. This work focuses on validating the ability of the Monte Carlo code MCNPX-PoliMi to reproduce measured neutron multiplicity results for a highly multiplicative sample. The benchmark experiment for this validation consists of a 4.5-kg sphere of plutonium metal that was moderated by various thicknesses of polyethylene. The detector system was the nPod, which contains a bank of 15 3He detectors. Simulations of the experiments were compared to the actual measurements and several sources of potential bias in the simulation were evaluated. The analysis included the effects of detector dead time, source-detector distance, density, and adjustments made to the value of {nu}-bar in the data libraries. Based on this analysis it was observed that a 1.14% decrease in the evaluated value of {nu}-bar for 239Pu in the ENDF-VII library substantially improved the accuracy of the simulation.

  12. Solar Flare Measurements with STIX and MiSolFA

    E-Print Network [OSTI]

    Casadei, Diego

    2014-01-01

    Solar flares are the most powerful events in the solar system and the brightest sources of X-rays, often associated with emission of particles reaching the Earth and causing geomagnetic storms, giving problems to communication, airplanes and even black-outs. X-rays emitted by accelerated electrons are the most direct probe of solar flare phenomena. The Micro Solar-Flare Apparatus (MiSolFA) is a proposed compact X-ray detector which will address the two biggest issues in solar flare modeling. Dynamic range limitations prevent simultaneous spectroscopy with a single instrument of all X-ray emitting regions of a flare. In addition, most X-ray observations so far are inconsistent with the high anisotropy predicted by the models usually adopted for solar flares. Operated at the same time as the STIX instrument of the ESA Solar Orbiter mission, at the next solar maximum (2020), they will have the unique opportunity to look at the same flare from two different directions: Solar Orbiter gets very close to the Sun wit...

  13. C-Myc negatively controls the tumor suppressor PTEN by upregulating miR-26a in glioblastoma multiforme cells

    SciTech Connect (OSTI)

    Guo, Pin; Nie, Quanmin; Lan, Jin; Ge, Jianwei [Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127 (China)] [Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127 (China); Qiu, Yongming, E-mail: qiuzhoub@hotmail.com [Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127 (China) [Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127 (China); Shanghai Institute of Head Trauma, Shanghai 200127 (China); Mao, Qing, E-mail: maoq@netease.com [Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127 (China) [Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127 (China); Shanghai Institute of Head Trauma, Shanghai 200127 (China)

    2013-11-08

    Highlights: •The c-Myc oncogene directly upregulates miR-26a expression in GBM cells. •ChIP assays demonstrate that c-Myc interacts with the miR-26a promoter. •Luciferase reporter assays show that PTEN is a specific target of miR-26a. •C-Myc–miR-26a suppression of PTEN may regulate the PTEN/AKT pathway. •Overexpression of c-Myc enhances the proliferative capacity of GBM cells. -- Abstract: The c-Myc oncogene is amplified in many tumor types. It is an important regulator of cell proliferation and has been linked to altered miRNA expression, suggesting that c-Myc-regulated miRNAs might contribute to tumor progression. Although miR-26a has been reported to be upregulated in glioblastoma multiforme (GBM), the mechanism has not been established. We have shown that ectopic expression of miR-26a influenced cell proliferation by targeting PTEN, a tumor suppressor gene that is inactivated in many common malignancies, including GBM. Our findings suggest that c-Myc modulates genes associated with oncogenesis in GBM through deregulation of miRNAs via the c-Myc–miR-26a–PTEN signaling pathway. This may be of clinical relevance.

  14. Proceedings of the 88th Annual Meeting (held June 18-23 in San Antonio, TX), Air and Waste Management Association, Pittsburgh, Pennsylvania, June 1995 Paper No. 95-7.02 1995 H.C. Frey

    E-Print Network [OSTI]

    Frey, H. Christopher

    and Waste Management Association June 18-23, San Antonio, TX In: Proceedings of the 88th Annual Meeting Air and Waste Management Association Pittsburgh, Pennsylvania #12;Proceedings of the 88th Annual Meeting (held June 18-23 in San Antonio, TX), Air and Waste Management Association, Pittsburgh, Pennsylvania, June

  15. miR-196a targets netrin 4 and regulates cell proliferation and migration of cervical cancer cells

    SciTech Connect (OSTI)

    Zhang, Jie; Zheng, Fangxia; Yu, Gang; Yin, Yanhua; Lu, Qingyang

    2013-11-01

    Highlights: •miR-196a was overexpressed in cervical cancer tissue compared to normal tissue. •miR-196a expression elevated proliferation and migration of cervical cancer cells. •miR-196a inhibited NTN4 expression by binding 3?-UTR region of NTN4 mRNA. •NTN4 inversely correlated with miR-196a expression in cervical tissue and cell line. •NTN4 expression was low in cervical cancer tissue compared to normal tissue. -- Abstract: Recent research has uncovered tumor-suppressive and oncogenic potential of miR-196a in various tumors. However, the expression and mechanism of its function in cervical cancer remains unclear. In this study, we assess relative expression of miR-196a in cervical premalignant lesions, cervical cancer tissues, and four cancer cell lines using quantitative real-time PCR. CaSki and HeLa cells were treated with miR-196a inhibitors, mimics, or pCDNA/miR-196a to investigate the role of miR-196a in cancer cell proliferation and migration. We demonstrated that miR-196a was overexpressed in cervical intraepithelial neoplasia 2–3 and cervical cancer tissue. Moreover, its expression contributes to the proliferation and migration of cervical cancer cells, whereas inhibiting its expression led to a reduction in proliferation and migration. Five candidate targets of miR-196a chosen by computational prediction and Cervical Cancer Gene Database search were measured for their mRNA in both miR-196a-overexpressing and -depleted cancer cells. Only netrin 4 (NTN4) expression displayed an inverse association with miR-196a. Fluorescent reporter assays revealed that miR-196a inhibited NTN4 expression by targeting one binding site in the 3?-untranslated region (3?-UTR) of NTN4 mRNA. Furthermore, qPCR and Western blot assays verified NTN4 expression was downregulated in cervical cancer tissues compared to normal controls, and in vivo mRNA level of NTN4 inversely correlated with miR-196a expression. In summary, our findings provide new insights about the functional role of miR-196a in cervical carcinogenesis and suggested a potential use of miR-196a for clinical diagnosis and as a therapeutic target.

  16. DOE - Office of Legacy Management -- Madison - IL 26

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouth DakotaRobbins and Myers CoMadison - IL 26 FUSRAP Considered Sites

  17. DOE - Office of Legacy Management -- Vapofier Corp - IL 25

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouth DakotaRobbins and Myers Co -VA 03 VirginiaVapofier Corp - IL

  18. Paper submitted to the Winter ASME Meeting, Nov. 27-Dec. 2, 1988, Chicago, IL. CONF-881120 --1 2

    E-Print Network [OSTI]

    Harilal, S. S.

    Power Program Argonne National Laboratory 9700 S. Caes Ave., Argonne, IL 60439 USA ABSTRACT Very high

  19. BANDO DI SELEZIONE PER IL CONFERIMENTO DI ASSEGNI PER LO SVOLGIMENTO DI ATTIVIT DI RICERCA DI CATEGORIA B TIPOLOGIA II

    E-Print Network [OSTI]

    Di Pillo, Gianni

    cerebrale, psicopatologia e risposta ai trattamenti", presso il Dipartimento di Scienze e Biotecnologie

  20. miR-421 induces cell proliferation and apoptosis resistance in human nasopharyngeal carcinoma via downregulation of FOXO4

    SciTech Connect (OSTI)

    Chen, Liang; Department of Otolaryngology, Guangzhou General Hospital of PLA Guangzhou Command, Guangzhou 510010 ; Tang, Yanping; Wang, Jian; Yan, Zhongjie; Xu, Ruxiang

    2013-06-14

    Highlights: •miR-421 is upregulated in nasopharyngeal carcinoma. •miR-421 induces cell proliferation and apoptosis resistance. •FOXO4 is a direct and functional target of miR-421. -- Abstract: microRNAs have been demonstrated to play important roles in cancer development and progression. Hence, identifying functional microRNAs and better understanding of the underlying molecular mechanisms would provide new clues for the development of targeted cancer therapies. Herein, we reported that a microRNA, miR-421 played an oncogenic role in nasopharyngeal carcinoma. Upregulation of miR-421 induced, whereas inhibition of miR-421 repressed cell proliferation and apoptosis resistance. Furthermore, we found that upregulation of miR-421 inhibited forkhead box protein O4 (FOXO4) signaling pathway following downregulation of p21, p27, Bim and FASL expression by directly targeting FOXO4 3?UTR. Additionally, we demonstrated that FOXO4 expression is critical for miR-421-induced cell growth and apoptosis resistance. Taken together, our findings not only suggest that miR-421 promotes nasopharyngeal carcinoma cell proliferation and anti-apoptosis, but also uncover a novel regulatory mechanism for inactivation of FOXO4 in nasopharyngeal carcinoma.

  1. Single-molecule modeling of mRNA degradation by miRNA: Lessons from data

    E-Print Network [OSTI]

    Celine Sin; Davide Chiarugi; Angelo Valleriani

    2014-10-20

    Recent experimental results on the effect of miRNA on the decay of its target mRNA have been analyzed against a previously hypothesized single molecule degradation pathway. According to that hypothesis, the silencing complex (miRISC) first interacts with its target mRNA and then recruits the protein complexes associated with NOT1 and PAN3 to trigger deadenylation (and subsequent degradation) of the target mRNA. Our analysis of the experimental decay patterns allowed us to refine the structure of the degradation pathways at the single molecule level. Surprisingly, we found that if the previously hypothesized network was correct, only about 7% of the target mRNA would be regulated by the miRNA mechanism, which is inconsistent with the available knowledge. Based on systematic data analysis, we propose the alternative hypothesis that NOT1 interacts with miRISC before binding to the target mRNA. Moreover, we show that when miRISC binds alone to the target mRNA, the mRNA is degraded more slowly, probably through a deadenylation-independent pathway. The new biochemical pathway we propose both fits the data and paves the way for new experimental work to identify new interactions.

  2. Published in Proceedings of Digital Libraries 95, Austin, TX, June, 1995, pp. 39-48. Collection Maintenance in the Digital Library

    E-Print Network [OSTI]

    Ackerman, Mark S.

    Published in Proceedings of Digital Libraries Ô95, Austin, TX, June, 1995, pp. 39-48. Collection Maintenance in the Digital Library Mark S. Ackerman Roy T. Fielding Information and Computer Science Maintenance will be critical to digital libraries, especially those that promote broad access to diverse

  3. 1998 * Tsou, M. and Buttenfield, B.P. Client/Server Components and Metadata Objects for Distributed Geographic Information Services. Proceedings, GIS/LIS '98, Fort Worth, TX,

    E-Print Network [OSTI]

    Tsou, Ming-Hsiang

    Geographic Information Services. Proceedings, GIS/LIS '98, Fort Worth, TX, November, 1998: 590-599. CLIENT management of geographic information is pushing the GIS community to establish an open GIS architecture/server components underlie specification of task-oriented programming, and the modularization of GIS software

  4. THE OUTER EDGE OF THE KUIPER BELT. J. M. Hahn, Lunar and Planetary Institute, Houston TX 77058, USA, (hahn@lpi.usra.edu).

    E-Print Network [OSTI]

    Hahn, Joseph M.

    THE OUTER EDGE OF THE KUIPER BELT. J. M. Hahn, Lunar and Planetary Institute, Houston TX 77058, USA, (hahn@lpi.usra.edu). One of the more curious features of the Kuiper Belt is the apparent dearth of Kuiper Belt Objects (KBOs) orbiting the Sun beyond 50 AU with modest eccentricities and incli- nations, e

  5. November 15, 2006 IMACS 2006, College Station, TX 2006 -p. 1/18 A third order scheme for Hamilton-Jacobi

    E-Print Network [OSTI]

    Popov, Peter

    November 15, 2006 IMACS 2006, College Station, TX 2006 - p. 1/18 A third order scheme for Hamilton-Jacobi/18 Presentation outline s Brief overview of numerical methods for Hamilton-Jacobi equations s A conforming, piecewise quadratic scheme on triangular meshes, with local evolution for Hamilton-Jacobi equations

  6. ION GNSS 2006, Fort Worth TX, 26-29 September 2006 1/14 Integrated GPS/INS System for Pedestrian Navigation in a

    E-Print Network [OSTI]

    Calgary, University of

    ION GNSS 2006, Fort Worth TX, 26-29 September 2006 1/14 Integrated GPS/INS System for Pedestrian research is focused on integrated IMU/GPS navigation systems for pedestrian and vehicular navigation. Dr evaluates the performance of a shoe/foot mounted inertial system for pedestrian navigation application. Two

  7. PROJECT NAME: MEMPHIS AVE. DAM (EPWU Dam #4-TX07017) 1. Provide the name of all non-Federal interests planning to act as the sponsor, including

    E-Print Network [OSTI]

    US Army Corps of Engineers

    PROJECT NAME: MEMPHIS AVE. DAM (EPWU Dam #4-TX07017) 1. Provide the name of all non. The purpose for the feasibility study is to determine the need to update/upgrade the dam in order to assist (NFIP), which allows for flood insurance discounts to local residents. #12;Image 1: Dam location

  8. PROJECT NAME: SCENIC DRIVE DAM (EPWUDam #6-TX07019) 1. Provide the name of all non-Federal interests planning to act as the sponsor, including

    E-Print Network [OSTI]

    US Army Corps of Engineers

    PROJECT NAME: SCENIC DRIVE DAM (EPWUDam #6-TX07019) 1. Provide the name of all non. The purpose for the feasibility study is to determine the need to update/upgrade the dam in order to assist (NFIP), which allows for flood insurance discounts to local residents. #12;Image 1: Dam location

  9. PROJECT NAME: SAN DIEGO DAM (TX.07314) 1. Provide the name of all non-Federal interests planning to act as the sponsor, including

    E-Print Network [OSTI]

    US Army Corps of Engineers

    PROJECT NAME: SAN DIEGO DAM (TX.07314) 1. Provide the name of all non-Federal interests planning for the feasibility study is to detennine the need to update/upgrade the dam in order to assist in our effmis), which allows for flood insurance discounts to local residents. #12;Image 1: Dam location and affected

  10. PROJECT NAME: MOREHEAD AVE. DAM (EPWU Dam #2-TX07015) 1. Provide the name of all non-Federal interests planning to act as the sponsor, including

    E-Print Network [OSTI]

    US Army Corps of Engineers

    PROJECT NAME: MOREHEAD AVE. DAM (EPWU Dam #2- TX07015) 1. Provide the name of all non. The purpose for the feasibility study is to determine the need to update/upgrade the dam in order to assist (NFIP), which allows for flood insurance discounts to local residents. #12;Image 1: Dam location

  11. PROJECT NAME: CLIFF ST. DAM (EPWU Dam #10-TX07023) 1. Provide the name of all non-Federal interests planning to act as the sponsor, including

    E-Print Network [OSTI]

    US Army Corps of Engineers

    PROJECT NAME: CLIFF ST. DAM (EPWU Dam #10- TX07023) 1. Provide the name of all non. The purpose for the feasibility study is to determine the need to update/upgrade the dam in order to assist (NFIP), which allows for flood insurance discounts to local residents. #12;Image 1: Dam location

  12. PROJECT NAME: TREMONT AVE. DAM (EPWUDam #7-TX07020) 1. Provide the name of all non-Federal interests planning to act as the sponsor, including

    E-Print Network [OSTI]

    US Army Corps of Engineers

    PROJECT NAME: TREMONT AVE. DAM (EPWUDam #7- TX07020) 1. Provide the name of all non. The purpose for the feasibility study is to determine the need to update/upgrade the dam in order to assist (NFIP), which allows for flood insurance discounts to local residents. #12;Image 1: Dam location

  13. PROJECT NAME: MURCHISON AVE. DAM (EPWUDam #8--TX07021) 1. Provide the name of all non-Federal interests planning to act as the sponsor, including

    E-Print Network [OSTI]

    US Army Corps of Engineers

    PROJECT NAME: MURCHISON AVE. DAM (EPWUDam #8--TX07021) 1. Provide the name of all non. The purpose for the feasibility study is to determine the need to update/upgrade the dam in order to assist (NFIP), which allows for flood insurance discounts to local residents. #12;Image 1: Dam location

  14. PROJECT NAME: OHIO ST. RESERVOIR DAM (TX.09511) 1. Provide the name of all non-Federal interests planning to act as the sponsor, including

    E-Print Network [OSTI]

    US Army Corps of Engineers

    PROJECT NAME: OHIO ST. RESERVOIR DAM (TX.09511) 1. Provide the name of all non-Federal interests for the feasibility study is to determine the need to update/upgrade the dam in order to assist in our efforts), which allows for flood insurance discounts to local residents. #12;Image 1: Dam location and affected

  15. THE SECULAR EVOLUTION OF THE PRIMORDIAL KUIPER BELT. J. M. Hahn, Lunar and Planetary Institute, Houston TX 77058, USA, (hahn@lpi.usra.edu).

    E-Print Network [OSTI]

    Hahn, Joseph M.

    THE SECULAR EVOLUTION OF THE PRIMORDIAL KUIPER BELT. J. M. Hahn, Lunar and Planetary Institute, Houston TX 77058, USA, (hahn@lpi.usra.edu). The Kuiper Belt is a vast swarm of comets orbiting at the Solar System's outer edge. This Belt is comprised of debris that was left over from the epoch of planet

  16. Protein kinase CK2 modulates IL-6 expression in inflammatory breast cancer

    SciTech Connect (OSTI)

    Drygin, Denis, E-mail: ddrygin@cylenepharma.com; Ho, Caroline B.; Omori, Mayuko; Bliesath, Joshua; Proffitt, Chris; Rice, Rachel; Siddiqui-Jain, Adam; O'Brien, Sean; Padgett, Claire; Lim, John K.C.; Anderes, Kenna; Rice, William G.; Ryckman, David

    2011-11-11

    Highlights: Black-Right-Pointing-Pointer We examine the potential cross-talk between CK2 and IL-6. Black-Right-Pointing-Pointer Inhibition of CK2 by siRNA or CX-4945 inhibits expression of IL-6 in models of IBC. Black-Right-Pointing-Pointer Treatment of IBC patient in the clinic with CX-4945 reduces her IL-6 plasma levels. Black-Right-Pointing-Pointer We demonstrate that CK2 is a potential therapeutic target for IL-6 driven diseases. -- Abstract: Inflammatory breast cancer is driven by pro-angiogenic and pro-inflammatory cytokines. One of them Interleukin-6 (IL-6) is implicated in cancer cell proliferation and survival, and promotes angiogenesis, inflammation and metastasis. While IL-6 has been shown to be upregulated by several oncogenes, the mechanism behind this phenomenon is not well characterized. Here we demonstrate that the pleotropic Serine/Threonine kinase CK2 is implicated in the regulation of IL-6 expression in a model of inflammatory breast cancer. We used siRNAs targeted toward CK2 and a selective small molecule inhibitor of CK2, CX-4945, to inhibit the expression and thus suppress the secretion of IL-6 in in vitro as well as in vivo models. Moreover, we report that in a clinical trial, CX-4945 was able to dramatically reduce IL-6 levels in plasma of an inflammatory breast cancer patient. Our data shed a new light on the regulation of IL-6 expression and position CX-4945 and potentially other inhibitors of CK2, for the treatment of IL-6-driven cancers and possibly other diseases where IL-6 is instrumental, including rheumatoid arthritis.

  17. Association study of schizophrenia and IL-2 receptor {beta} chain gene

    SciTech Connect (OSTI)

    Nimgaonkar, V.L.; Yang, Z.W.; Zhang, X.R.; Brar, J.S.

    1995-10-09

    A case-control association study was conducted in Caucasian patients with schizophrenia (DSM-III-R, n = 42) and unaffected controls (n = 47) matched for ethnicity and area of residence. Serum interleukin-2 receptor (IL-2R) concentrations, as well as a dinucleotide repeat polymorphism in the IL-2RP chain gene, were examined in both groups. No significant differences in IL-2R concentrations or in the distribution of the polymorphism were noted. This study does not support an association between schizophrenia and the IL-2RP gene locus, contrary to the suggestive evidence from linkage analysis in multicase families. 17 refs., 2 tabs.

  18. Alternating magnetic anisotropy of Li2(Li1–xTx)N(T=Mn,Fe,Co,andNi)

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Jesche, A.; Ke, L.; Jacobs, J. L.; Harmon, B.; Houk, R. S.; Canfield, P. C.

    2015-05-11

    Substantial amounts of the transition metals Mn, Fe, Co, and Ni can be substituted for Li in single crystalline Li2(Li1–xTx)N. Isothermal and temperature-dependent magnetization measurements reveal local magnetic moments with magnitudes significantly exceeding the spin-only value. The additional contributions stem from unquenched orbital moments that lead to rare-earth-like behavior of the magnetic properties. Accordingly, extremely large magnetic anisotropies have been found. Most notably, the magnetic anisotropy alternates as easy plane?easy axis?easy plane?easy axis when progressing from T = Mn ? Fe ? Co ? Ni. This behavior can be understood based on a perturbation approach in an analytical, single-ion model.more »As a result, the calculated magnetic anisotropies show surprisingly good agreement with the experiment and capture the basic features observed for the different transition metals.« less

  19. Cost-Effective Energy Efficiency Measures for 15% Above 2009 IECC Code-Compliant House for Residential Buildings in TX 

    E-Print Network [OSTI]

    Kim, H.; Baltazar, J.C.; Haberl, J.; Lewis, C.; Yazdani, B.

    2011-01-01

    ?Compliant House in TX 11th ICEBO Conference Oct. 18 ? 20, 2011 11 17 Energy Efficiency Measures (3/4) DHW System Measures 11.Tankless gas water heater 12.Removal of pilot light from DHW system 13.Solar DHW system ? 32 sq. ft. collector, 65 gal tank 14....5% 2.9% 3.0% 2.2% 2.9% 2.3% 4.0% 3.3% 2.2% ? 4.0% 4.3% 11 Tankless Gas Water Heater (from .594 to .748 Energy Factor) 1.6% 1.7% 1.7% 1.6% 1.7% 1.7% 1.6% 1.7% 1.6% 1.6% ? 1.7% 1.6% 1.7% 1.7% 1.6% 1.7% 1.6% 1.5% 1.5% ? 1.7% 1.5% 12 Removal of Pilot...

  20. Ion-lithium collision dynamics studied with an in-ring MOTReMi

    E-Print Network [OSTI]

    Fischer, D; Goullon, J; Grieser, M; Hubele, R; de Jesus, V L B; Kelkar, A; LaForge, A; Lindenblatt, H; Misra, D; Najjari, B; Schneider, K; Schulz, M; Sell, M; Wang, X

    2012-01-01

    We present a novel experimental tool allowing for kinematically complete studies of break-up processes of laser-cooled atoms. This apparatus, the 'MOTReMi', is a combination of a magneto-optical trap (MOT) and a Reaction Microscope (ReMi). Operated in an ion-storage ring, the new setup enables to study the dynamics in swift ion-atom collisions on an unprecedented level of precision and detail. In first experiments on collisions with 1.5 MeV/amu O$^{8+}$-Li the pure ionization of the valence electron as well as ionization-excitation of the lithium target has been investigated.

  1. NETL F 451.1/1-1, Categorical Exclusion Designation Form

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    TX; Trimeric Corporation: Champaign, IL and Buda, TX. FESCCStorage Division Bruce Brown Brine Extraction and Treatment Strategies to Enhance Pressure Management... Project...

  2. Company City State Contact Info 21st Century Plastics Corporation Potterville MI www.21stcpc.com

    E-Print Network [OSTI]

    McGaughey, Alan

    Engineered Plastics, LLC Auburn Hills MI www.deltaengineeredplastics.com Detrex Corporation.dutchlandplastics.com E & O Tool & Plastics, Inc. Elk River MN www.eoplastics.com E & T Plastic Rubber & Plastics Corp. Farmington Hills MI www.exoticautomation.com F & D Plastics, Inc

  3. Roles of the MicroRNA miR-31 in tumor metastasis and an experimental system for the unbiased discovery of genes relevant for breast cancer metastasis

    E-Print Network [OSTI]

    Valastyan, Scott J. (Scott John)

    2010-01-01

    In these studies, the microRNA miR-31 was identified as a potent inhibitor of breast cancer metastasis. miR-31 expression levels were inversely associated with the propensity to develop metastatic disease in human breast ...

  4. Reprinted from the Proceedings of the 1998 ASEE North Central Section Meeting, University of Detroit Mercy, Detroit, MI, April 3-4, 1998. ( Best Paper Award )

    E-Print Network [OSTI]

    Bell, John T.

    of Detroit Mercy, Detroit, MI, April 3-4, 1998. ( Best Paper Award ) VIRTUAL REALITY IN CHEMICAL ENGINEERING

  5. A NOD2NALP1 complex mediates caspase-1-dependent IL-1 secretion in response to

    E-Print Network [OSTI]

    Nizet, Victor

    A NOD2­NALP1 complex mediates caspase-1-dependent IL-1 secretion in response to Bacillus anthracis February 20, 2008) NOD2, a NOD-like receptor (NLR), is an intracellular sensor of bacterial muramyl, the molecular mechanism by which NOD2 can stimulate IL-1 secretion, and its biological significance were

  6. En quoi Turing a-t-il chang ma vie de chercheur ?

    E-Print Network [OSTI]

    van Tiggelen, Bart

    1912-2012 ALAN TURING En quoi Turing a-t-il changé ma vie de chercheur ? PIERRE LESCANNE (LIP, CNRS scientifique génial, prolifique et polyvalent. Que se serait-il passé alors ? 1Les machines à computer d'Alan Turing, Bulletin de SPECIF n63 (avril 2010) #12;

  7. Cell type-specific roles of Jak3 in IL-2-induced proliferative signal transduction

    SciTech Connect (OSTI)

    Fujii, Hodaka . E-mail: hodaka@med.nyu.edu

    2007-03-16

    Binding of interleukin-2 (IL-2) to its specific receptor induces activation of two members of Jak family protein tyrosine kinases, Jak1 and Jak3. An IL-2 receptor (IL-2R)-reconstituted NIH 3T3 fibroblast cell line proliferates in response to IL-2 only when hematopoietic lineage-specific Jak3 is ectopically expressed. However, the mechanism of Jak3-dependent proliferation in the fibroblast cell line is not known. Here, I showed that Jak3 expression is dispensable for IL-2-induced activation of Jak1 and Stat proteins and expression of nuclear proto-oncogenes in the IL-2R-reconstituted fibroblast cell line. Jak3 expression markedly enhanced these IL-2-induced signaling events. In contrast, Jak3 expression was essential for induction of cyclin genes involved in the G1-S transition. These data suggest a critical role of Jak3 in IL-2 signaling in the fibroblast cell line and may provide further insight into the cell type-specific mechanism of cytokine signaling.

  8. Blockage of IL-6 secretion in glia by lead and mercury 

    E-Print Network [OSTI]

    Pourrajabi, Nima Matthew

    2003-01-01

    , we constructed an IL-6-EGFP chimera and transiently transfected rat C6 glioma cells and rat primary astroglia. IL-6-EGFP signal in transfected cultures exposed to Pb, Hg, or anti-oligos against GRP78 was detected with a bio-image fluorescence...

  9. BANDO PER IL RECLUTAMENTO DI UN RICERCATORE CON RAPPORTO DI LAVORO A TEMPO DETERMINATO TIPOLOGIA A

    E-Print Network [OSTI]

    Di Pillo, Gianni

    Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" Visti i DD.MM. 4.10.2000 e 9.1.2001 concernenti.03.2012; Vista la Convenzione stipulata tra il Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" e la Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" nella seduta del 28.05.2013; Visto il parere

  10. BANDO PER IL RECLUTAMENTO DI UN RICERCATORE CON RAPPORTO DI LAVORO A TEMPO DETERMINATO TIPOLOGIA A

    E-Print Network [OSTI]

    Di Pillo, Gianni

    A Bando RTD n. 01/2014 Il Direttore del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer delibere del Consiglio del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 18.12.2013 e Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" il SSD BIO/09 ha pertinenza prevalente D E C R E

  11. Bando per il reclutamento di un Ricercatore a Tempo Determinato APPROVAZIONE ATTI

    E-Print Network [OSTI]

    Di Pillo, Gianni

    Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" Visto il Regolamento per il reclutamento di Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" dell'8 giugno 2010 e del 30 settembre 2010; Vista delibera del Consiglio di Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 19 novembre

  12. IL DIRIGENTE VISTA la Legge 2 dicembre 1991, n. 390 Norme sul diritto agli studi universitari;

    E-Print Network [OSTI]

    »; VISTO il Regolamento per l'Amministrazione, la Finanza e la Contabilità, emanato con D.R. n. 82/AG del studenti meritevoli mediante rimborso di una parte del costo sostenuto dagli studenti interessati ad dei requisiti necessari per parteciparvi. Il rimborso previsto sarà pari al 75% del costo del corso

  13. De novo design of an IL-4 antagonist and its structure at 1.9

    E-Print Network [OSTI]

    Stroud, Robert

    De novo design of an IL-4 antagonist and its structure at 1.9 Å Sherry L. LaPorte*, Charles M. Stroud, December 17, 2004 An IL-4 antagonist was designed based on structural and biochem- ical analysis at the level of side-chains and secondary structure element interactions. de novo protein design helical bundle

  14. Start S Morgan St End 1933 W Polk St, Chicago, IL 60612

    E-Print Network [OSTI]

    Spirtes, Peter

    Start S Morgan St End 1933 W Polk St, Chicago, IL 60612 When 10/5/11 after 9:09pm Duration 19 mins total Loading... ©2011 Google - Map data ©2011 Google, Sanborn - S Morgan St to 1933 W Polk St, Chicago District Walk to 1933 W Polk St, Chicago, IL 60612 Beta: Use caution ­ This route may be missing sidewalks

  15. IL-8 Production in Human Lung Fibroblasts and Epithelial Cells Activated by the Pseudomonas Autoinducer

    E-Print Network [OSTI]

    Springer, Timothy A.

    IL-8 Production in Human Lung Fibroblasts and Epithelial Cells Activated by the Pseudomonas is caused, in part, by the produc- tion of the chemokine IL-8, which recruits neutrophils into the lung. These findings support the concept that the severe lung damage that accompanies P. aeruginosa infections

  16. Centro di Ricerca Il Direttore del Centro di Ricerca Hydro-Eco

    E-Print Network [OSTI]

    Di Pillo, Gianni

    Centro di Ricerca HYDRO-ECO HYDRO-ECO . Il Direttore del Centro di Ricerca Hydro-Eco Visto il D Vista la Delibera del Consiglio del Centro Hydro-Eco del 15/9/2010 Vista la Delibera del Senato Ricerca Hydro-Eco è così composta: Rosario Cantelli Angelo Chianese Paolo De Filippis Stefania Panero

  17. BENDIX SYSTEMS DIVISION ANN AIt 1 o I, MI CH NO. Plan for Operational Contingency

    E-Print Network [OSTI]

    Rathbun, Julie A.

    8/29/66 BENDIX SYSTEMS DIVISION ANN AIt 1 o I, MI CH NO. ATM-396 Plan for Operational Contingency of the operational plans and the system design and to study methods of recovery from partial failure through the use. ATM- 396 RIV.MO. A I I f..r I (I IOperational Contingency Study 2 PAGI OP

  18. New Loops! MiTeGen* 50MicroMountsTM consist of a thin microfabricated

    E-Print Network [OSTI]

    Meagher, Mary

    New Loops! MiTeGen* 50µMicroMountsTM consist of a thin microfabricated polyimide film attached to a solid non-magnetic stainless steel pin. The film is polyimide, which is used in Kapton® tape and is employed for X- ray transparent windows on X-ray beam lines. The film is curved by wrapping polyimide film

  19. 2000 JAPAN-USA Symposium on Flexible Automation July 23-26, 2000, Ann Arbor, MI

    E-Print Network [OSTI]

    Saitou, Kazuhiro "Kazu"

    2000 JAPAN-USA Symposium on Flexible Automation July 23-26, 2000, Ann Arbor, MI 2000JUSFA-US1 OFF-LINE ERROR RECOVERY LOGIC SYNTHESIS IN AUTOMATED ASSEMBLY LINES BY USING GENETIC PROGRAMMING Cem M. Baydar by the experts or automated error recovery logic controllers embedded in the system. The previous work

  20. An HNF4a-miRNA Inflammatory Feedback Circuit Regulates

    E-Print Network [OSTI]

    An HNF4a-miRNA Inflammatory Feedback Circuit Regulates Hepatocellular Oncogenesis Maria, once this circuit is activated, it maintains suppression of HNF4a and sustains oncogenesis. Systemic recapitulate hepatic oncogenesis in various animal models (He et al., 2010). In addition, the inflammatory

  1. AUSTRALIAN. N~TIONAL UNIVE~SITY DEPARTMENTO:miNUCLEAR PFf-y'SICS

    E-Print Network [OSTI]

    Chen, Ying

    AUSTRALIAN. N~TIONAL UNIVE~SITY DEPARTMENTO:miNUCLEAR PFf-y'SICS 14UD TANK OPENING REPORT/iNo. 51 functions for which it provides power. An order was . immediately placed with N.E.C. for 28 perspex bars microamp hours of b.d.p. generation than its predicted lifetime. In preparation for the next opening

  2. MSU CENTER FOR REGIONAL FOOD SYSTEMS 480 WILSON ROAD, EAST LANSING, MI 48824

    E-Print Network [OSTI]

    AN ANNOTATED BIBLIOGRAPHY ON STRUCTURAL RACISM PRESENT IN THE U.S. FOOD SYSTEM JUNE 2015 #12;Michigan State University Center for Regional Food Systems Structural Racism Present in the U.S. Food System 2 AUTHORS Anel on structural racism present in the U.S. food system. East Lansing, MI: MSU Center for Regional Food Systems

  3. Request for Alternative Activity for PLI Credit Last Name First Name M.I.

    E-Print Network [OSTI]

    Connors, Daniel A.

    Request for Alternative Activity for PLI Credit Full Name: Last Name First Name M.I. Email Address information for Coordinator of Program: Requesting Alternate Activity credit for which PLI Track (Choose one): Verification Information Email Address: College of Engineering Student Information Alternate Activity

  4. MI FARM TO SCHOOL GRANTEES 2014-2015 PROGRAM YEAR AND PREVIOUS GRANTEES

    E-Print Network [OSTI]

    MI FARM TO SCHOOL GRANTEES 2014-2015 PROGRAM YEAR AND PREVIOUS GRANTEES FOODSYSTEMS.MSU.EDU 2014-2015 GRANTEES School/ district/ program County Current Grant Years as a grantee A&W Daycare Wayne Planning 1 TO SCHOOL GRANTEES (2011/12 ­ 2013/14) School/ district/ program County Grant Type(s) Grant Years All Aboard

  5. Polyphenol-induced Anti-inflammatory and Cytotoxic Activities in Breast and Colon Cancer: Potential Role of miRNA's in Cell Survival and Inflammation 

    E-Print Network [OSTI]

    Banerjee, Nivedita

    2013-12-11

    growth in athymic BALB/c nude mice with BT474 xenografts. Interactions of Pg with miR-27a- ZBTB10-Sp and miR-155-SHIP-1-PI3K axes and mango miR126/PI3K/AKT axis were identified. In addition, pomegranate and plum polyphenols exerted cytotoxic and anti...

  6. SAE 1983 Transactions, Paper No. 830200, pp. 1.810-1.816 International Congress & Exposition, Detroit, Mi., Feb. 28-March 4, 1983

    E-Print Network [OSTI]

    Radcliffe, Clark J.

    , Detroit, Mi., Feb. 28- March 4, 1983 #12;SAE 1983 Transactions, Paper No. 830200, pp. 1.810-1.816 International Congress & Exposition, Detroit, Mi., Feb. 28- March 4, 1983 #12;SAE 1983 Transactions, Paper No. 830200, pp. 1.810-1.816 International Congress & Exposition, Detroit, Mi., Feb. 28- March 4, 1983 Fig. 2

  7. MiR-18a regulates the proliferation, migration and invasion of human glioblastoma cell by targeting neogenin

    SciTech Connect (OSTI)

    Song, Yichen; Wang, Ping; Zhao, Wei; Yao, Yilong; Liu, Xiaobai; Ma, Jun; Xue, Yixue; Liu, Yunhui

    2014-05-15

    MiR-17-92 cluster has recently been reported as an oncogene in some tumors. However, the association of miR-18a, an important member of this cluster, with glioblastoma remains unknown. Therefore, this study aims to investigate the expression of miR-18a in glioblastoma and its role in biological behavior of U87 and U251 human glioblastoma cell lines. Quantitative RT-PCR results showed that miR-18a was highly expressed in glioblastoma tissues and U87 and U251 cell lines compared with that in human brain tissues and primary normal human astrocytes, and the expression levels were increased along with the rising pathological grades of glioblastoma. Neogenin was identified as the target gene of miR-18a by dual-luciferase reporter assays. RT-PCR and western blot results showed that its expression levels were decreased along with the rising pathological grades of glioblastoma. Inhibition of miR-18a expression was established by transfecting exogenous miR-18a inhibitor into U87 and U251 cells, and its effects on the biological behavior of glioblastoma cells were studied using CCK-8 assay, transwell assay and flow cytometry. Inhibition of miR-18a expression in U87 and U251 cells significantly up-regulated neogenin, and dramatically suppressed the abilities of cell proliferation, migration and invasion, induced cell cycle arrest and promoted cellular apoptosis. Collectively, these results suggest that miR-18a may regulate biological behavior of human glioblastoma cells by targeting neogenin, and miR-18a can serve as a potential target in the treatment of glioblastoma. - Highlights: • MiR-18a was highly expressed in glioblastoma tissues and U87 and U251 cell lines. • Neogenin was identified as the target gene of miR-18a. • Neogenin expressions were decreased along with the rising pathological grades of glioblastoma. • Inhibition of miR-18a suppressed biological behavior of glioma cells by up-regulating neogenin.

  8. miR-7 and miR-218 epigenetically control tumor suppressor genes RASSF1A and Claudin-6 by targeting HoxB3 in breast cancer

    SciTech Connect (OSTI)

    Li, Qiaoyan; Zhu, Fufan; Chen, Puxiang

    2012-07-20

    Highlights: Black-Right-Pointing-Pointer Both miR-7 and miR-218 down-regulates HoxB3 expression by targeting the 3 Prime -UTR of HoxB3 mRNA. Black-Right-Pointing-Pointer A reverse correlation between the levels of endogenous miR-7, miR218 and HoxB3 expression. Black-Right-Pointing-Pointer Epigenetic changes involve in the reactivation of HoxB3. Black-Right-Pointing-Pointer Both miRNAs inhibits the cell cycle and clone formation of breast cancer cells. -- Abstract: Many microRNAs have been implicated as key regulators of cellular growth and differentiation and have been found to dysregulate proliferation in human tumors, including breast cancer. Cancer-linked microRNAs also alter the epigenetic landscape by way of DNA methylation and post-translational modifications of histones. Aberrations in Hox gene expression are important for oncogene or tumor suppressor during abnormal development and malignancy. Although recent studies suggest that HoxB3 is critical in breast cancer, the putative role(s) of microRNAs impinging on HoxB3 is not yet fully understood. In this study, we found that the expression levels of miR-7 and miR-218 were strongly and reversely associated with HoxB3 expression. Stable overexpression of miR-7 and miR-218 was accompanied by reactivation of tumor suppressor genes including RASSF1A and Claudin-6 by means of epigenetic switches in DNA methylation and histone modification, giving rise to inhibition of the cell cycle and clone formation of breast cancer cells. The current study provides a novel link between overexpression of collinear Hox genes and multiple microRNAs in human breast malignancy.

  9. University of Houston -Office of Scholarships and Financial Aid 5000 Gulf Freeway, ERP 2 Room 224, Houston, TX 77204-2010 Phone: (713)743-1010 Fax: (713)743-9098

    E-Print Network [OSTI]

    Azevedo, Ricardo

    TCHAPP University of Houston - Office of Scholarships and Financial Aid 5000 Gulf Freeway, ERP 2 of Scholarships and Financial Aid 5000 Gulf Freeway, ERP 2 Room 224, Houston, TX 77204-2010 Phone: (713

  10. AVVISO PUBBLICO DI SELEZIONE PER IL CONFERIMENTO DI UN INCARICO DI COLLABORAZIONE COORDINATA E CONTINUATIVA DA ATTIVARE PER LE ESIGENZE

    E-Print Network [OSTI]

    Di Pillo, Gianni

    e sviluppo di algoritmi efficienti per il problema del bilancio energetico cellulare. Articolo 1 La molecolari reali e sviluppo di algoritmi efficienti per il problema del bilancio energetico cellulare

  11. L’indisciplina e il suo contenuto sociale da Collodi alle riletture di Carmelo Bene e Luigi Malerba

    E-Print Network [OSTI]

    Righi, Andrea

    2011-01-01

    Bergson, Henri. 1982. ll riso. Saggio sul significato delproppiana, si genera il riso spontaneo che Henri Bergson

  12. [12.7.20044:01pm] [101114] [Page No. 101] {Eserial}4393-van-Pelt/3d/vanPelt-tx08.3d Van Pelt

    E-Print Network [OSTI]

    Stryker, Michael

    . Prog Brain Res.147:103-114. Corrections indicated in red. #12;[12.7.2004­4:01pm] [101­114] [Page No[12.7.2004­4:01pm] [101­114] [Page No. 101] {Eserial}4393-van-Pelt/3d/vanPelt-tx08.3d Van Pelt U N Research, Vol. 147 ISSN 0079-6123 Copyright ß 2005 Elsevier BV. All rights reserved CHAPTER 8 Molecular

  13. PIANO DI RIQUALIFICAZIONE AMBIENTALE E PAESAGGISTICA DEL TERMOVALORIZZATORE DI DESIO TERMOVALORIZZATORE DI DESIO (MI) BRIANZA ENERGIA E AMBIENTE SPA

    E-Print Network [OSTI]

    Columbia University

    TERMOVALORIZZATORE DI DESIO (MI) ­ BRIANZA ENERGIA E AMBIENTE SPA Impianto di costruito negli anni '70 per lo. · Energia elettrica prodotta: 13.000.000 KWh/anno. LAND S.r.l. Landscape Architecture Nature Development

  14. Prot. n. 1174/2013 SELEZIONE PER IL CONFERIMENTO DI N. 1 ASSEGNO PER LO

    E-Print Network [OSTI]

    categoria B ­ Tipologia II ­ Analisi di risposta sismica locale in aree edificate, analisi dell'interazione dell'edificato con il sottosuolo; valutazione degli effetti del non sincronismo dell'azione sismica

  15. Prot. n. 730/2014 SELEZIONE PER IL CONFERIMENTO DI N. 1 ASSEGNO PER LO

    E-Print Network [OSTI]

    ­ Tipologia I ­ Analisi di risposta sismica locale in aree edificate, analisi dell'interazione dell'edificato con il sottosuolo; valutazione degli effetti del non sincronismo dell'azione sismica sulle costruzioni

  16. Prot. n. 1167/2013 SELEZIONE PER IL CONFERIMENTO DI N. 1 ASSEGNO PER LO

    E-Print Network [OSTI]

    ­ Analisi di risposta sismica locale in aree edificate, analisi dell'interazione dell'edificato con il sottosuolo; valutazione degli effetti del non sincronismo dell'azione sismica sulle costruzioni; livelli di

  17. DEVELOPING METHODS FOR ANTAGONIZING TNF-? AND IL-1? IN THE CENTRAL NERVOUS SYSTEM 

    E-Print Network [OSTI]

    Hardin, Elizabeth Ashley

    2006-08-16

    harvested to examine the development of glucocorticoid resistance (GCR), a hallmark of SDR, in the TNF-? study only. The ELISA assay was not sensitive enough to the tissue levels of TNF-?, therefore successful antagonism was undetectable. In contrast, IL-1...

  18. Measurement of Pi-K Ratios from the NuMI Target

    SciTech Connect (OSTI)

    Seun, Sin Man; /Harvard U.

    2007-07-01

    Interactions of protons (p) with the NuMI (Neutrinos at the Main Injector) target are used to create the neutrino beam for the MINOS (Main Injector Neutrino Oscillation Search) Experiment. Using the MIPP (Main Injector Particle Production) experimental apparatus, the production of charged pions and kaons in p+NuMI interactions is studied. The data come from a sample of 2 x 10{sup 6} events obtained by MIPP using the 120 GeV/c proton beam from the Main Injector at Fermi National Accelerator Laboratory in Illinois, USA. Pions and kaons are identified by measurement in a Ring Imaging Cherenkov detector. Presented are measurements of {pi}{sup -}/{pi}{sup +}, K{sup -}/K{sup +}, {pi}{sup +}/K{sup +} and {pi}{sup -}/K{sup -} production ratios in the momentum range p{sub T} < 2 GeV/c transversely and 20 GeV/c < p{sub z} < 90 GeV/c longitudinally. Also provided are detailed comparisons of the MIPP NuMI data with the MIPP Thin Carbon data, the MIPP Monte Carlo simulation and the current MINOS models in the relevant momentum ranges.

  19. Targeting miR-21 enhances the sensitivity of human colon cancer HT-29 cells to chemoradiotherapy in vitro

    SciTech Connect (OSTI)

    Deng, Jun; Lei, Wan; Fu, Jian-Chun; Zhang, Ling; Li, Jun-He; Xiong, Jian-Ping

    2014-01-17

    Highlight: •MiR-21 plays a significant role in 5-FU resistance. •This role might be attributed to targeting of hMSH2 as well as TP and DPD via miR-21 targeted hMSH2. •Indirectly targeted TP and DPD to influence 5-FU chemotherapy sensitivity. -- Abstract: 5-Fluorouracil (5-FU) is a classic chemotherapeutic drug that has been widely used for colorectal cancer treatment, but colorectal cancer cells are often resistant to primary or acquired 5-FU therapy. Several studies have shown that miR-21 is significantly elevated in colorectal cancer. This suggests that this miRNA might play a role in this resistance. In this study, we investigated this possibility and the possible mechanism underlying this role. We showed that forced expression of miR-21 significantly inhibited apoptosis, enhanced cell proliferation, invasion, and colony formation ability, promoted G1/S cell cycle transition and increased the resistance of tumor cells to 5-FU and X radiation in HT-29 colon cancer cells. Furthermore, knockdown of miR-21 reversed these effects on HT-29 cells and increased the sensitivity of HT-29/5-FU to 5-FU chemotherapy. Finally, we showed that miR-21 targeted the human mutS homolog2 (hMSH2), and indirectly regulated the expression of thymidine phosphorylase (TP) and dihydropyrimidine dehydrogenase (DPD). These results demonstrate that miR-21 may play an important role in the 5-FU resistance of colon cancer cells.

  20. Are We Closing the School Discipline Gap?

    E-Print Network [OSTI]

    Losen, Daniel; Hodson, Cheri; Keith II, Michael A; Morrison, Katrina; Belway, Shakti

    2015-01-01

    FL), St. Louis (MO), Detroit (MI), Jefferson County (KY),County, FL; Dallas, TX; Detroit, MI; Fairfax, VA; Houston,CITY MO NORMANDY MO EAST DETROIT PUBLIC SCHOOLS MI TROTWOOD-

  1. PROCEDURA DI VALUTAZIONE COMPARATIVA PER IL RECLUTAMENTO DI N. 1 RICERCATORE CON RAPPORTO DI LAVORO A TEMPO DETERMINATO TIPOLOGIA A) PRESSO IL DIPARTIMENTO

    E-Print Network [OSTI]

    Di Pillo, Gianni

    A TEMPO DETERMINATO TIPOLOGIA A) PRESSO IL DIPARTIMENTO DI FISIOLOGIA E FARMACOLOGIA "VITTORIO ERSPAMER Commissione svolge i suoi lavori; - consegnati al Direttore del Dipartimento di Fisiologia e Farmacologia Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer", al fine di valutare i titoli del candidato e la

  2. Oncogenic role of miR-155 in anaplastic large cell lymphoma lacking the t(2;5) translocation

    E-Print Network [OSTI]

    Merkel, Olaf; Hamacher, Frank; Griessl, Robert; Grabner, Lisa; Schiefer, Ana-Iris; Prutsch, Nicole; Baer, Constance; Egger, Gerda; Schlederer, Michaela; Krenn, Peter William; Hartmann, Tanja Nicole; Simonitsch-Klupp, Ingrid; Plass, Christoph; Staber, Philipp; Moriggl, Richard; Turner, Suzanne D.; Greil, Richard; Kenner, Lukas

    2015-04-27

    of the germinal center response by microRNA-155. Science 2007; 316: 604-608. 44. Sabat R, Ouyang W, Wolk K. Therapeutic opportunities of the IL-22-IL-22R1 system. Nature reviews Drug discovery 2014; 13: 21-38. 45. Sanda T, Tyner JW, Gutierrez A, et al. TYK2...

  3. MiR-34a targets GAS1 to promote cell proliferation and inhibit apoptosis in papillary thyroid carcinoma via PI3K/Akt/Bad pathway

    SciTech Connect (OSTI)

    Ma, Yanfei; Qin, Huadong [Department of Fourth Surgery, the Second Affiliated Hospital of Harbin Medical University, 148 Xuefu Road, Nangang District, Harbin 150086 (China)] [Department of Fourth Surgery, the Second Affiliated Hospital of Harbin Medical University, 148 Xuefu Road, Nangang District, Harbin 150086 (China); Cui, Yunfu, E-mail: yfma77@126.com [Department of First Surgery, the Second Affiliated Hospital of Harbin Medical University, 148 Xuefu Road, Nangang District, Harbin 150086 (China)] [Department of First Surgery, the Second Affiliated Hospital of Harbin Medical University, 148 Xuefu Road, Nangang District, Harbin 150086 (China)

    2013-11-29

    Highlights: •MiR-34a is up- and GAS1 is down-regulated in papillary thyroid carcinoma. •GAS1 is a direct target for miR-34a. •MiR-34a promotes PTC cells proliferation and inhibits apoptosis through PI3K/Akt/Bad pathway. -- Abstract: MicroRNAs (miRNAs) are fundamental regulators of cell proliferation, differentiation, and apoptosis, and are implicated in tumorigenesis of many cancers. MiR-34a is best known as a tumor suppressor through repression of growth factors and oncogenes. Growth arrest specific1 (GAS1) protein is a tumor suppressor that inhibits cancer cell proliferation and induces apoptosis through inhibition of RET receptor tyrosine kinase. Both miR-34a and GAS1 are frequently down-regulated in various tumors. However, it has been reported that while GAS1 is down-regulated in papillary thyroid carcinoma (PTC), miR-34a is up-regulated in this specific type of cancer, although their potential roles in PTC tumorigenesis have not been examined to date. A computational search revealed that miR-34a putatively binds to the 3?-UTR of GAS1 gene. In the present study, we confirmed previous findings that miR-34a is up-regulated and GAS1 down-regulated in PTC tissues. Further studies indicated that GAS1 is directly targeted by miR-34a. Overexpression of miR-34a promoted PTC cell proliferation and colony formation and inhibited apoptosis, whereas knockdown of miR-34a showed the opposite effects. Silencing of GAS1 had similar growth-promoting effects as overexpression of miR-34a. Furthermore, miR-34a overexpression led to activation of PI3K/Akt/Bad signaling pathway in PTC cells, and depletion of Akt reversed the pro-growth, anti-apoptotic effects of miR-34a. Taken together, our results demonstrate that miR-34a regulates GAS1 expression to promote proliferation and suppress apoptosis in PTC cells via PI3K/Akt/Bad pathway. MiR-34a functions as an oncogene in PTC.

  4. MiR-145 is downregulated in human ovarian cancer and modulates cell growth and invasion by targeting p70S6K1 and MUC1

    SciTech Connect (OSTI)

    Wu, Huijuan; Xiao, ZhengHua; Wang, Ke; Liu, Wenxin; Hao, Quan

    2013-11-29

    Highlights: •MiR-145 is downregulated in human ovarian cancer. •MiR-145 targets p70S6K1 and MUC1. •p70S6K1 and MUC1 are involved in miR-145 mediated tumor cell growth and cell invasion, respectively. -- Abstract: MicroRNAs (miRNAs) are a family of small non-coding RNA molecules that regulate gene expression at post-transcriptional levels. Previous studies have shown that miR-145 is downregulated in human ovarian cancer; however, the roles of miR-145 in ovarian cancer growth and invasion have not been fully demonstrated. In the present study, Northern blot and qRT-PCR analysis indicate that miR-145 is downregulated in ovarian cancer tissues and cell lines, as well as in serum samples of ovarian cancer, compared to healthy ovarian tissues, cell lines and serum samples. Functional studies suggest that miR-145 overexpression leads to the inhibition of colony formation, cell proliferation, cell growth viability and invasion, and the induction of cell apoptosis. In accordance with the effect of miR-145 on cell growth, miR-145 suppresses tumor growth in vivo. MiR-145 is found to negatively regulate P70S6K1 and MUC1 protein levels by directly targeting their 3?UTRs. Importantly, the overexpression of p70S6K1 and MUC1 can restore the cell colony formation and invasion abilities that are reduced by miR-145, respectively. MiR-145 expression is increased after 5-aza-CdR treatment, and 5-aza-CdR treatment results in the same phenotype as the effect of miR-145 overexpression. Our study suggests that miR-145 modulates ovarian cancer growth and invasion by suppressing p70S6K1 and MUC1, functioning as a tumor suppressor. Moreover, our data imply that miR-145 has potential as a miRNA-based therapeutic target for ovarian cancer.

  5. EIS-0394: EPA Notice of Availability of the Draft Environmental...

    Broader source: Energy.gov (indexed) [DOE]

    Planning, Design, Construction and Operation a Coal Fueled Electric Power and Hydrogen Gas Production Plant, Four Alternative Sites: Mattoon, IL, Tuscola, IL, Jewett, TX and...

  6. Testing CPT conservation using the NuMI neutrino beam with the MINOS experiment

    SciTech Connect (OSTI)

    Auty, David John; /Sussex U.

    2010-05-01

    The MINOS experiment was designed to measure neutrino oscillation parameters with muon neutrinos. It achieves this by measuring the neutrino energy spectrum and flavor composition of the man-made NuMI neutrino beam 1km after the beam is formed and again after 735 km. By comparing the two spectra it is possible to measure the oscillation parameters. The NuMI beam is made up of 7.0% {bar {nu}}{sub {mu}}, which can be separated from the {nu}{sub {mu}} because the MINOS detectors are magnetized. This makes it possible to study {bar {nu}}{sub {mu}} oscillations separately from those of muon neutrinos, and thereby test CPT invariance in the neutrino sector by determining the {bar {nu}}{sub {mu}} oscillation parameters and comparing them with those for {nu}{sub {mu}}, although any unknown physics of the antineutrino would appear as a difference in oscillation parameters. Such a test has not been performed with beam {bar {nu}}{sub {mu}} before. It is also possible to produce an almost pure {bar {nu}}{sub {mu}} beam by reversing the current through the magnetic focusing horns of the NuMI beamline, thereby focusing negatively, instead of positively charged particles. This thesis describes the analysis of the 7% {bar {nu}}{sub {mu}} component of the forward horn current NuMI beam. The {bar {nu}}{sub {mu}} of a data sample of 3.2 x 10{sup 20} protons on target analysis found 42 events, compared to a CPT conserving prediction of 58.3{sub -7.6}{sup +7.6}(stat.){sub -3.6}{sup +3.6}(syst.) events. This corresponds to a 1.9 {sigma} deficit, and a best fit value of {Delta}{bar m}{sub 32}{sup 2} = 18 x 10{sup -3} eV{sup 2} and sin{sup 2} 2{bar {theta}}{sub 23} = 0.55. This thesis focuses particularly on the selection of {bar {nu}}{sub {mu}} events, and investigates possible improvements of the selection algorithm. From this a different selector was chosen, which corroborated the findings of the original selector. The thesis also investigates how the systematic errors affect the precision of {Delta}{bar m}{sub 32}{sup 2} and sin{sup 2} 2{bar {theta}}{sub 23}. Furthermore, it describes a study to determine the gains of the PMTs via the single-photoelectron spectrum. The results were used as a crosscheck of the gains determined at higher intensities by an LED-based light-injection system.

  7. AMENDMENT OF SOLICITATION/MODIFICATlON OF CONTRACT MI54 I See Block 16C I

    National Nuclear Security Administration (NNSA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal GasAdministration Medal01 Sandia National 1 PAGE 1 OF2 AMENDMENTNLUF1 82 Se elBabcockMI54

  8. Adrenaline promotes cell proliferation and increases chemoresistance in colon cancer HT29 cells through induction of miR-155

    SciTech Connect (OSTI)

    Pu, Jun [Department of General Surgery, Tangdu Hospital of the Fourth Military Medical University, Xi'an 710038 (China)] [Department of General Surgery, Tangdu Hospital of the Fourth Military Medical University, Xi'an 710038 (China); Bai, Danna [Department of Cardiology, 323 Hospital of PLA, Xi'an 710054 (China)] [Department of Cardiology, 323 Hospital of PLA, Xi'an 710054 (China); Yang, Xia [Department of Teaching and Medical Administration, Tangdu Hospital of the Fourth Military Medical University, Xi'an 710038 (China)] [Department of Teaching and Medical Administration, Tangdu Hospital of the Fourth Military Medical University, Xi'an 710038 (China); Lu, Xiaozhao [Department of Nephrology, The 323 Hospital of PLA, Xi'an 710054 (China)] [Department of Nephrology, The 323 Hospital of PLA, Xi'an 710054 (China); Xu, Lijuan, E-mail: 13609296272@163.com [Department of Nephrology, The 323 Hospital of PLA, Xi'an 710054 (China)] [Department of Nephrology, The 323 Hospital of PLA, Xi'an 710054 (China); Lu, Jianguo, E-mail: lujianguo029@yahoo.com.cn [Department of General Surgery, Tangdu Hospital of the Fourth Military Medical University, Xi'an 710038 (China)] [Department of General Surgery, Tangdu Hospital of the Fourth Military Medical University, Xi'an 710038 (China)

    2012-11-16

    Highlights: Black-Right-Pointing-Pointer Adrenaline increases colon cancer cell proliferation and its resistance to cisplatin. Black-Right-Pointing-Pointer Adrenaline activates NF{kappa}B in a dose dependent manner. Black-Right-Pointing-Pointer NF{kappa}B-miR-155 pathway contributes to cell proliferation and resistance to cisplatin. -- Abstract: Recently, catecholamines have been described as being involved in the regulation of cancer genesis and progression. Here, we reported that adrenaline increased the cell proliferation and decreased the cisplatin induced apoptosis in HT29 cells. Further study found that adrenaline increased miR-155 expression in an NF{kappa}B dependent manner. HT29 cells overexpressing miR-155 had a higher cell growth rate and more resistance to cisplatin induced apoptosis. In contrast, HT29 cells overexpressing miR-155 inhibitor displayed decreased cell proliferation and sensitivity to cisplatin induced cell death. In summary, our study here revealed that adrenaline-NF{kappa}B-miR-155 pathway at least partially contributes to the psychological stress induced proliferation and chemoresistance in HT29 cells, shedding light on increasing the therapeutic strategies of cancer chemotherapy.

  9. Characterization of Vadose Zone Sediments Below the TX Tank Farm: Boreholes C3830, C3831, C3832 and RCRA Borehole 299-W10-27

    SciTech Connect (OSTI)

    Serne, R. Jeffrey; Bjornstad, Bruce N.; Horton, Duane G.; Lanigan, David C.; Lindenmeier, Clark W.; Lindberg, Michael J.; Clayton, Ray E.; Legore, Virginia L.; Orr, Robert D.; Kutnyakov, Igor V.; Baum, Steven R.; Geiszler, Keith N.; Valenta, Michelle M.; Vickerman, Tanya S.

    2008-09-11

    This report was revised in September 2008 to remove acid-extractable sodium data from Tables 4.8, 4.28,4.43, and 4.59. The sodium data was removed due to potential contamination introduced during the acid extraction process. The rest of the text remains unchanged from the original report issued in April 2004. The overall goal of the Tank Farm Vadose Zone Project, led by CH2M HILL Hanford Group, Inc., is to define risks from past and future single-shell tank farm activities at Hanford. To meet this goal, CH2M HILL Hanford Group, Inc. tasked scientists from Pacific Northwest National Laboratory to perform detailed analyses on vadose zone sediments from within Waste Management Area (WMA) T-TX-TY. This report is the first of two reports written to present the results of these analyses. Specifically, this report contains all the geologic, geochemical, and selected physical characterization data collected on vadose zone sediment recovered from boreholes C3830, C3831, and C3832 in the TX Tank Farm, and from borehole 299-W-10-27 installed northeast of the TY Tank Farm.

  10. Assessment of radiological releases from the NuMI facility during MINOS and NOvA operations

    SciTech Connect (OSTI)

    Martens, Mike; /Fermilab

    2007-04-01

    This report makes projections of the radiological releases from the NuMI facility during operations for the MINOS and NO ?A experiments. It includes an estimate of the radionuclide levels released into the atmosphere and the estimated tritium and sodium-22 concentrations in the NuMI sump water and Fermilab pond system. The analysis was performed for NuMI operations with a beam power on target increased from the present 400 kW design up to a possible 1500 kW with future upgrades. The total number of protons on target was assumed to be 18 x 10{sup 20} after the completion of MINOS and 78 x 10{sup 20} after the completion of NO ?A.

  11. The MiMeS Survey of Magnetism in Massive Stars: Introduction and overview

    E-Print Network [OSTI]

    Wade, G A; Alecian, E; Grunhut, J H; Petit, V; de Batz, B; Bohlender, D A; Cohen, D H; Henrichs, H F; Kochukhov, O; Landstreet, J D; Manset, N; Martins, F; Mathis, S; Oksala, M E; Owocki, S P; Rivinius, Th; Shultz, M E; Sundqvist, J O; Townsend, R H D; ud-Doula, A; Bouret, J -C; Braithwaite, J; Briquet, M; Carciofi, A C; David-Uraz, A; Folsom, C P; Fullerton, A W; Leroy, B; Marcolino, W L F; Moffat, A F J; Nazé, Y; Aurière, M; Bagnulo, S; Bailey, J D; Barbá, R H; Blazère, A; Böhm, T; Catala, C; Donati, J -F; Ferrario, L; Harrington, D; Howarth, I D; Ignace, R; Kaper, L; Lüftinger, T; Prinja, R; Vink, J S; Weiss, W W; Yakunin, I

    2015-01-01

    The MiMeS project is a large-scale, high resolution, sensitive spectropolarimetric investigation of the magnetic properties of O and early B type stars. Initiated in 2008 and completed in 2013, the project was supported by 3 Large Program allocations, as well as various programs initiated by independent PIs and archival resources. Ultimately, over 4800 circularly polarized spectra of 560 O and B stars were collected with the instruments ESPaDOnS at the Canada-France-Hawaii Telescope, Narval at the T\\'elescope Bernard Lyot, and HARPSpol at the European Southern Observatory La Silla 3.6m telescope, making MiMeS by far the largest systematic investigation of massive star magnetism ever undertaken. In this paper, the first in a series reporting the general results of the survey, we introduce the scientific motivation and goals, describe the sample of targets, review the instrumentation and observational techniques used, explain the exposure time calculation designed to provide sensitivity to surface dipole fields...

  12. Upgrade of the Minos+ Experiment Data Acquisition for the High Energy NuMI Beam Run

    E-Print Network [OSTI]

    William Badgett; Steve R. Hahn; Donatella Torretta; Jerry Meier; Jeffrey Gunderson; Denise Osterholm; David Saranen

    2015-06-06

    The Minos+ experiment is an extension of the Minos experiment at a higher energy and more intense neutrino beam, with the data collection having begun in the fall of 2013. The neutrino beam is provided by the Neutrinos from the Main Injector (NuMI) beam-line at Fermi National Accelerator Laboratory (Fermilab). The detector apparatus consists of two main detectors, one underground at Fermilab and the other in Soudan, Minnesota with the purpose of studying neutrino oscillations at a base line of 735 km. The original data acquisition system has been running for several years collecting data from NuMI, but with the extended run from 2013, parts of the system needed to be replaced due to obsolescence, reliability problems, and data throughput limitations. Specifically, we have replaced the front-end readout controllers, event builder, and data acquisition computing and trigger processing farms with modern, modular and reliable devices with few single points of failure. The new system is based on gigabit Ethernet TCP/IP communication to implement the event building and concatenation of data from many front-end VME readout crates. The simplicity and partitionability of the new system greatly eases the debugging and diagnosing process. The new system improves throughput by about a factor of three compared to the old system, up to 800 megabits per second, and has proven robust and reliable in the current run.

  13. Training Session: Euless, TX

    Broader source: Energy.gov [DOE]

    This 3.5-hour training provides builders with a comprehensive review of zero energy-ready home construction including the business case, detailed specifications, and opportunities to be recognized...

  14. Houston, TX Trinity Uni

    E-Print Network [OSTI]

    Natelson, Douglas

    Baton Rou jnovak@PI Lin Luo The Dow C 2301 Brazo Freeport, T lluo2@dow NACS Rep Mike Reyn Shell Inter pecially if yo sh. e colleagues am to them ur Treasurer ould be mad nt registrati ip. : The best 00 t). WCS p (last #12;3 7 8 8 9 10 10 1 12 2 3 3 7:30 AM 8:25 AM 8:30 AM 9:15 AM 0:00 AM 0:30 AM 1

  15. D&TX

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouth DakotaRobbins and Myers Co -VANaval ,, *' ;x-L*Qwner contacted0*.

  16. ~tx410.ptx

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorkingLosThe 26thI D- 6 0 4 2 rz machine |NNSA0202(2).pdf More THURSDAY,

  17. ~tx421.ptx

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorkingLosThe 26thI D- 6 0 4 2 rz machine |NNSA0202(2).pdf More THURSDAY,

  18. cis-and trans-Regulation of miR163 and Target Genes Confers Natural Variation of Secondary Metabolites in Two Arabidopsis

    E-Print Network [OSTI]

    Tholl, Dorothea

    involved in secondary metabolite biosynthetic pathways that are inducible by a fungal elicitor, alamethicin and secondary metabolite profiles. We suggest that cis- and trans-regulation of miRNA and other genes providescis- and trans-Regulation of miR163 and Target Genes Confers Natural Variation of Secondary

  19. Curcumin promotes apoptosis in A549/DDP multidrug-resistant human lung adenocarcinoma cells through an miRNA signaling pathway

    SciTech Connect (OSTI)

    Zhang, Jian, E-mail: zhangjian197011@yahoo.com [Department of Respiratory Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032 (China)] [Department of Respiratory Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032 (China); Zhang, Tao [Department of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038 (China)] [Department of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038 (China); Ti, Xinyu; Shi, Jieran; Wu, Changgui; Ren, Xinling [Department of Respiratory Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032 (China)] [Department of Respiratory Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032 (China); Yin, Hong, E-mail: yinnhong@yahoo.com [The Medical Image Center, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032 (China)] [The Medical Image Center, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032 (China)

    2010-08-13

    Research highlights: {yields} Curcumin had anti-cancer effects on A549/DDP multidrug-resistant human lung adenocarcinoma cells {yields} Curcumin promotes apoptosis in A549/DDP cells through a miRNA signaling pathway {yields} Curcumin induces A549/DDP cell apoptosis by downregulating miR-186* {yields} miR-186* may serve as a potential gene therapy target for refractory lung cancer that is sensitive to curcumin -- Abstract: Curcumin extracted from the rhizomes of Curcuma longa L. has been shown to have inhibitory effects on cancers through its anti-proliferative and pro-apoptotic activities. Emerging evidence demonstrates that curcumin can overcome drug resistance to classical chemotherapies. Thus, the mechanisms underlying the anti-tumor activities of curcumin require further study. In our study, we first demonstrated that curcumin had anti-cancer effects on A549/DDP multidrug-resistant human lung adenocarcinoma cells. Further studies showed that curcumin altered miRNA expression; in particular, significantly downregulated the expression of miR-186* in A549/DDP. In addition, transfection of cells with a miR-186* inhibitor promoted A549/DDP apoptosis, and overexpression of miR-186* significantly inhibited curcumin-induced apoptosis in A549/DDP cells. These observations suggest that miR-186* may serve as a potential gene therapy target for refractory lung cancer that is sensitive to curcumin.

  20. -i&k'il (uI//X -8^O^O --o ~u^ 1MASTER

    E-Print Network [OSTI]

    Oak Ridge National Laboratory

    conditioners. Also, recent increases in the real prices of energy augment these savings. For this country, September 28-October 1, 1981, Los Angeles, California. #12;-2- resources needed for the residential-i&k'il (§uI//X - 8^O^O --o ~u^ 1MASTER GASrHEAT-PUMP DEVELOPMENT F. A. Creswick a Energy Division

  1. Premio Perini Navi S.p.A. IL COMITATO LEONARDO ITALIAN QUALIT COMMITTE HA

    E-Print Network [OSTI]

    Segatti, Antonio

    1 Premio Perini Navi S.p.A. IL COMITATO LEONARDO ­ ITALIAN QUALITÀ COMMITTE ­ HA DELIBERATO DI DELEGATO DI PERINI NAVI SPA. - ANNO 2011 - "Progetto di un natante ad uso tender per un'imbarcazione a vela dalla direzione della Perini Navi S.p.A. FINALITÀ: Premiare i due migliori progetti relativi ad un

  2. IL NUOVO CIMENTO Vol. ?, N. ? ? Atomic theory in cesium, implications for searches for physics

    E-Print Network [OSTI]

    Safronova, Marianna

    IL NUOVO CIMENTO Vol. ?, N. ? ? Atomic theory in cesium, implications for searches for physics on weak nucleon-nucleon coupling obtained from the cesium anapole moment and those obtained from other by the parity selection rule, such as the 6s - 7s transition in cesium. Several different effects contributing

  3. Understanding Deep Web Search Interfaces: A Survey Ritu Khare Yuan An Il-Yeol Song

    E-Print Network [OSTI]

    Song, Il-Yeol

    Understanding Deep Web Search Interfaces: A Survey Ritu Khare Yuan An Il-Yeol Song The i presents a survey on the major approaches to search interface understanding. The Deep Web consists of data of Deep Web. Automatic access to these data requires an automatic understanding of search interfaces

  4. Prot. n. 909/2014 SELEZIONE PER IL CONFERIMENTO DI N. 1 ASSEGNO PER LO

    E-Print Network [OSTI]

    categoria B ­ Tipologia II ­ Analisi di risposta sismica locale in aree edificate, analisi dell'interazione dell'edificato con il sottosuolo; valutazione degli effetti del non sincronismo dell'azione sismica viene chiesta la cultura in campo di risposta sismica locale finalizzata alle interazioni con le

  5. MILLING-GRINDING-DRILLING AND SLOTTING ATTACHMENT (VERSA-M IL)

    E-Print Network [OSTI]

    Gellman, Andrew J.

    TC 9-524 Chapter 9 MILLING-GRINDING-DRILLING AND SLOTTING ATTACHMENT (VERSA-M IL) GENERAL DESCRIPTION The milling-grinding-drilling and slotting attachment is commonly referred to as a Versa-purpose machines. With the different attachments that are available with the unit, drilling, shaping, milling

  6. 1. Risolvete il seguente sistema lineare utilizzando l'algoritmo di Gauss con pivoting per colonne

    E-Print Network [OSTI]

    Guerrini, Carla

    Esercizi 1. Risolvete il seguente sistema lineare utilizzando l'algoritmo di Gauss con pivoting per colonne: 2x1 + x2 + 2x3 = 5 2x1 + x2 - 3x3 = 0 3x1 - x2 + 7x3 = 9 2. Utilizzate l'algoritmo di Gauss senza

  7. Bando n. 01/2012 AVVISO PUBBLICO DI SELEZIONE PER IL CONFERIMENTO DI UN INCARICO DI

    E-Print Network [OSTI]

    Di Pillo, Gianni

    FISIOLOGIA E FARMACOLOGIA "VITTORIO ERSPAMER" VISTO - Visto il Regolamento per l'affidamento di incarichi di fronte alle esigenze rappresentate dal Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer svolgimento dell'attività di cui all'art. 1 del presente avviso a favore del Dipartimento di Fisiologia e

  8. (Bando collab. 2014 -04) AVVISO PUBBLICO DI SELEZIONE PER IL CONFERIMENTO DI UN INCARICO DI

    E-Print Network [OSTI]

    Di Pillo, Gianni

    FISIOLOGIA E FARMACOLOGIA "VITTORIO ERSPAMER" VISTO - Visto il Regolamento per l'affidamento di incarichi di disponibilità, né competenze adeguate per fare fronte alle esigenze rappresentate dal Dipartimento di Fisiologia presente avviso a favore del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" della "Sapienza

  9. Bando n. 04_2012 AVVISO PUBBLICO DI SELEZIONE PER IL CONFERIMENTO DI UN INCARICO DI

    E-Print Network [OSTI]

    Di Pillo, Gianni

    FISIOLOGIA E FARMACOLOGIA "VITTORIO ERSPAMER" VISTO - Visto il Regolamento per l'affidamento di incarichi di competenze adeguate per fare fronte alle esigenze rappresentate dal Dipartimento di Fisiologia e Farmacologia di Fisiologia e Farmacologia "Vittorio Erspamer" della "Sapienza" Università di Roma. Articolo 1 La

  10. NOMINA COMMISSIONE GIUDICATRICE PER IL CONFERIMENTO DI INCARICO DI PROFESSORE STRAORDINARIO CON RAPPORTO DI LAVORO

    E-Print Network [OSTI]

    Di Pillo, Gianni

    RAPPORTO DI LAVORO A TEMPO DETERMINATO Il Direttore del Dipartimento di Fisiologia e Farmacologia "Vittorio Dipartimento di Fisiologia e Farmacologia; VISTA la delibera del Consiglio di Dipartimento di Fisiologia e Fisiologia e Farmacologia di Sapienza Università di Roma, è così composta: #12;membri effettivi: prof. Paolo

  11. (Bando collab. 2014 -01) AVVISO PUBBLICO DI SELEZIONE PER IL CONFERIMENTO DI UN INCARICO DI

    E-Print Network [OSTI]

    Di Pillo, Gianni

    DIPARTIMENTO DI FISIOLOGIA E FARMACOLOGIA "VITTORIO ERSPAMER" VISTO - Visto il Regolamento per l'affidamento di esigenze rappresentate dal Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer"; - Ravvisata all'art. 1 del presente avviso a favore del Dipartimento di Fisiologia e Farmacologia "Vittorio

  12. BANDO PER IL RECLUTAMENTO DI UN RICERCATORE CON RAPPORTO DI LAVORO A TEMPO DETERMINATO TIPOLOGIA A

    E-Print Network [OSTI]

    Di Pillo, Gianni

    di Fisiologia e Farmacologia "Vittorio Erspamer" Visti i DD.MM. 4.10.2000 e 9.1.2001 concernenti la a disposizione del Dipartimento; Viste le delibere del Consiglio del Dipartimento di Fisiologia e Farmacologia ed esami» - n° 75 del 26 settembre 2014; Considerato che per il Dipartimento di Fisiologia e

  13. Bando n. 02_2013 AVVISO PUBBLICO DI SELEZIONE PER IL CONFERIMENTO DI UN INCARICO DI

    E-Print Network [OSTI]

    Di Pillo, Gianni

    FISIOLOGIA E FARMACOLOGIA "VITTORIO ERSPAMER" VISTO - Visto il Regolamento per l'affidamento di incarichi di alle esigenze rappresentate dal Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer Fisiologia e Farmacologia "Vittorio Erspamer" della "Sapienza" Università di Roma. Articolo 1 La presente

  14. BANDO PER IL RECLUTAMENTO DI UN RICERCATORE CON RAPPORTO DI LAVORO A TEMPO DETERMINATO TIPOLOGIA A

    E-Print Network [OSTI]

    Di Pillo, Gianni

    A Bando RTD n. 02/2014 Il Direttore del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer Fisiologia e Farmacologia "Vittorio Erspamer" di n. 1 posto di ricercatore con rapporto di lavoro a tempo economica della quota di competenza a carico del Dipartimento di Fisiologia e Farmacologia "Vittorio

  15. (Bando collab. 2014 -03) AVVISO PUBBLICO DI SELEZIONE PER IL CONFERIMENTO DI UN INCARICO DI

    E-Print Network [OSTI]

    Di Pillo, Gianni

    FISIOLOGIA E FARMACOLOGIA "VITTORIO ERSPAMER" VISTO - Visto il Regolamento per l'affidamento di incarichi di alle esigenze rappresentate dal Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer'attività di cui all'art. 1 del presente avviso a favore del Dipartimento di Fisiologia e Farmacologia

  16. (Bando collab. 2014 -02) AVVISO PUBBLICO DI SELEZIONE PER IL CONFERIMENTO DI UN INCARICO DI

    E-Print Network [OSTI]

    Di Pillo, Gianni

    FISIOLOGIA E FARMACOLOGIA "VITTORIO ERSPAMER" VISTO - Visto il Regolamento per l'affidamento di incarichi di esigenze rappresentate dal Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer"; - Ravvisata presente avviso a favore del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" della "Sapienza

  17. Bando n. 02_2012 AVVISO PUBBLICO DI SELEZIONE PER IL CONFERIMENTO DI UN INCARICO DI

    E-Print Network [OSTI]

    Di Pillo, Gianni

    FISIOLOGIA E FARMACOLOGIA "VITTORIO ERSPAMER" VISTO - Visto il Regolamento per l'affidamento di incarichi di adeguate per fare fronte alle esigenze rappresentate dal Dipartimento di Fisiologia e Farmacologia Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" della "Sapienza" Università di Roma. Articolo 1

  18. BANDO PER IL RECLUTAMENTO DI UN RICERCATORE CON RAPPORTO DI LAVORO A TEMPO DETERMINATO TIPOLOGIA A

    E-Print Network [OSTI]

    Di Pillo, Gianni

    Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" Visti i DD.MM. 4.10.2000 e 9.1.2001 concernenti" a disposizione del Dipartimento; Viste le delibere del Consiglio del Dipartimento di Fisiologia e Farmacologia del 6 giugno 2014; Considerato che per il Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer

  19. Industry MeetIng for sustaInabIlIty Native Forests

    E-Print Network [OSTI]

    ­ NATIONAL CONFEDERATION OF INDUSTRY ­ BRAZIL Robson Braga de Andrade President EDUCATION AND TECHNOLOGY: CNi, 2012. 54 p.: il (rio+20 sectorial fascicle) 1.sustainability 2. United Nations Conference) .................................................... 24 Figure 7. leading Exporter states of sawn Hardwoods in brazil (2011) ............... 24 Figure 8

  20. Differential regulation of RANTES and IL-8 expression in lung adenocarcinoma cells

    E-Print Network [OSTI]

    Boyer, Edmond

    1 Differential regulation of RANTES and IL-8 expression in lung adenocarcinoma cells Corinne expression in lung adenocarcinoma cells HALauthormanuscriptinserm-00143972,version1 HAL author manuscript Lung Cancer 56, 2 (2007) 167-74 #12;2 Summary In lung adenocarcinoma, expression of Regulated upon

  1. Il Ministro dellIstruzione, dell''Universit e della Allegato A (v. art. 4)

    E-Print Network [OSTI]

    Di Pillo, Gianni

    assicurano alle Università livelli di qualità, efficienza ed efficacia dei corsi di studio, si fa riferimento agli indicatori appresso indicati. Indicatori di efficienza: a. l'efficienza nell'utilizzo del acquisiti per studente; b. l'efficienza in termini di numero di studenti iscritti e frequentanti il corso di

  2. Start S Morgan St End 1933 W Polk St, Chicago, IL 60612

    E-Print Network [OSTI]

    Spirtes, Peter

    Start S Morgan St End 1933 W Polk St, Chicago, IL 60612 When 10/5/11 after 9:00pm Duration 17 mins total Loading... ©2011 Google - Map data ©2011 Google, Sanborn - S Morgan St to 1933 W Polk St, Chicago mins Harrison & Morgan Bus - 7 - Harrison towards Central 9:07pm - 9:14pm (7 mins, 10 stops) Polk

  3. IL NUOVO CIMENTO Vol. ?, N. ? ? The Liverpool Telescope Automatic Pipeline for Realtime GRB

    E-Print Network [OSTI]

    Gomboc, Andreja

    IL NUOVO CIMENTO Vol. ?, N. ? ? The Liverpool Telescope Automatic Pipeline for Real­time GRB pipeline. PACS 95.55.Cs -- Ground­based ultraviolet, optical and infrared telescopes. PACS 95.75.Mn of the system is the subsequent pipelined data reduction, analysis and automatic identification of possible GRB

  4. 21 aprile 2009 Il piccolo AGILE cattura i raggi gamma dalla super-stella

    E-Print Network [OSTI]

    ». Fenomeni che AGILE è riuscito a osservare nella banda di energia intorno a 100 MeV grazie allo strumento realizzato in collaborazione con l'Istituto Nazionale di Fisica Nucleare. AGILE, il cui nome è l'acronimo di), progettato dall'INAF (Istituto Nazionale di Astrofisica), dall'INFN (Istituto Nazionale di Fisica Nucleare

  5. miR-206 is down-regulated in breast cancer and inhibits cell proliferation through the up-regulation of cyclinD2

    SciTech Connect (OSTI)

    Zhou, Jing; Tian, Ye; Li, Juan; Lu, Binbin; Sun, Ming; Zou, Yanfen; Kong, Rong; Luo, Yanhong; Shi, Yongguo; Wang, Keming; Ji, Guozhong

    2013-04-05

    Highlights: ? miR-206 was downexpressed in tumor samples compared with matched normal samples. ? Enhanced expression of miR-206 could inhibit breast cancer growth in vitro. ? Luciferase confirmed miR-206 functions as an anti-oncogene by targeting cyclinD2. ? A reverse correlation between miR-206 and cyclinD2 in breast cancer was found. -- Abstract: MicroRNAs act as important gene regulators in human genomes, and their aberrant expression is linked to many malignancies. Aberrant expression of miR-206 has been frequently reported in cancer studies; however, the role and mechanism of its function in breast cancer remains unclear. Quantitative real-time PCR was performed to detect the relative expression levels of miR-206 in breast cancer and normal breast tissues. Lower expression of miR-206 in breast cancer tissues was associated with larger tumour size and a more advanced clinical stage. Further in vitro observations showed that the enforced expression of miR-206 in MCF-7 breast cancer cells inhibited cell growth by blocking the G1/S transition and suppressed cell proliferation and colony formation, implying that miR-206 functions as a tumour suppressor in the progression of breast cancer. Interestingly, Luciferase assays first revealed that miR-206 inhibited cyclinD2 expression by targeting two binding sites in the 3?-untranslated region of cyclinD2 mRNA. qRT-PCR and Western blot assays verified that miR-206 reduced cyclinD2 expression at both the mRNA and protein levels. A reverse correlation between miR-206 and cyclinD2 expression was noted in breast cancer tissues. Altogether, our results identify a crucial tumour suppressive role of miR-206 in the progression of breast cancer, at least partly via up-regulation of the expression of cyclinD2, and suggest that miR-206 might be a candidate prognostic predictor or an anticancer therapeutic target for breast cancer patients.

  6. Matematica con Esercitazioni 22. 11. 2014 1. Risolvere il seguente sistema lineare con l'algoritmo di Gauss-Jordan

    E-Print Network [OSTI]

    Achilles, Rüdiger

    Matematica con Esercitazioni 22. 11. 2014 1. Risolvere il seguente sistema lineare con l'algoritmo l'eliminazione di Gauss e considerare il sistema equivalente triangolare. 4. Si usi l'algoritmo di Suggerimento: Si usi l'algoritmo di Gauss per ridurre le matrici a scala per righe. 6. (Bramanti

  7. Algorithms II 89-322 Instructor: Prof. Amihood Amir 03-531-8770 amir@cs.biu.ac.il

    E-Print Network [OSTI]

    Amir, Amihood

    " Algorithms II 89-322 Instructor: Prof. Amihood Amir 03-531-8770 amir@cs.biu.ac.il Webpage: http://u.cs.biu.ac.il/~amir/AlgII/alg2.html Office hours: by appointment Text: Any advanced algorithms book. Example: Cormen, Leiserson, Rivest and Stein (2nd edition). Class notes. Prerequisites: Algorithms I, Complexity. Transparencies

  8. BANDO N. 01-2010 PER IL RECLUTAMENTO DI UN RICERCATORE CON RAPPORTO DI LAVORO A TEMPO DETERMINATO

    E-Print Network [OSTI]

    Di Pillo, Gianni

    Il Direttore del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" Visto il Regolamento Fisiologia e Farmacologia "Vittorio Erspamer" e la Fondazione "Enrico ed Enrica Sovena", con sede in Roma costituenti chimici"; Vista la Delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia "Vittorio

  9. Du dmon blond Jesus Price, les rfrences religieuses abondent lorsqu'il est ques-tion du Canadien de Montral.

    E-Print Network [OSTI]

    Charette, André

    Du «démon blond» à «Jesus Price», les références religieuses abondent lorsqu'il est ques- tion du Canadien de Montréal. Du culte de la sainte Flanelle à celui de «Jesus Price» en passant par les fantômes». «Jésus Price» est parfois le «sauveur» de l'équipe, alors qu'à d'autres moments il vit un «cal- vaire» et

  10. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne: OFFICE OF STUDENT FINANCIAL AID · The Welcome Center · P. O. Box 2340 · 42 West Warren · Detroit, MI

  11. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · www FINANCIAL AID · The Welcome Center · P. O. Box 2340 · 42 West Warren · Detroit, MI 48202-0340 If this form

  12. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · www OF STUDENT FINANCIAL AID · The Welcome Center · P. O. Box 2340 · 42 West Warren · Detroit, MI 48202-0340 3

  13. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne · Detroit, MI 48202-0340 Student's First Name 9-digit WSU Student ID # Student's Last Name Phone Number 3

  14. NUEX16 Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne FINANCIAL AID · The Welcome Center · P. O. Box 2340 · 42 West Warren · Detroit, MI 48202-0340 Student

  15. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · www · Detroit, MI 48202-0340 If this form is required it will be listed in Pipeline, under "My Requirements" 3

  16. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · www Warren · Detroit, MI 48202-0340 If this form is required it will be listed in Pipeline, under "My

  17. Manuscript was received April 15, 2007. Irina Hossain is with the Department of Electrical and Computer Engineering, Wayne State University, Detroit, MI. Phone: 651-815-5828; Fax: 651-

    E-Print Network [OSTI]

    Mahmud, Syed Masud

    and Computer Engineering, Wayne State University, Detroit, MI. Phone: 651-815-5828; Fax: 651- 305-4549; e State University, Detroit, MI. Phone: 313-577-3855; Fax: 313-577-5845; e-mail: smahmud

  18. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne Warren · Detroit, MI 48202-0340 Student's First Name 9-digit WSU Student ID # Student's Last Name Phone

  19. CTFS16 Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne · Detroit, MI 48202-0340 3/2015 Student's First Name 9-digit WSU Student ID # Student's Last Name Phone

  20. VRHS14 Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · www: OFFICE OF STUDENT FINANCIAL AID · The Welcome Center · P. O. Box 2340 · 42 West Warren · Detroit, MI

  1. Hanna, A., J. Vukovich, S. Arunachalam, D. Loughlin, H.C. Frey, J. Touma, J. Irwin, and V. Isakov, "Assessment of Uncertainty in Benzene Concentration Estimates in the Houston, TX, Area," Proceedings, Annual Meeting of the Air &

    E-Print Network [OSTI]

    Frey, H. Christopher

    , "Assessment of Uncertainty in Benzene Concentration Estimates in the Houston, TX, Area," Proceedings, Annual & Waste Management Association, Pittsburgh, PA, June 2004 1 Assessment of Uncertainty in Benzene for a particular urban area. We present the results of a case study involving benzene emissions in the Houston area

  2. Photometry of symbiotic stars XI. EG And, Z And, BF Cyg, CH Cyg, CI Cyg, V1329 Cyg, TX CVn, AG Dra, RW Hya, QW Sge, IV Vir and the LMXB V934 Her

    E-Print Network [OSTI]

    A. Skopal; T. Pribulla; M. Vanko; Z. Velic; E. Semkov; M. Wolf; A. Jones

    2004-02-06

    We present new photometric observations of EG And, Z And, BF Cyg, CH Cyg, CI Cyg, V1329 Cyg, TX CVn, AG Dra, RW Hya, AR Pav, AG Peg, AX Per, QW Sge, IV Vir and the peculiar M giant V934 Her. The current issue gathers observations of these objects to December 2003.

  3. Network Modeling Identifies Molecular Functions Targeted by miR-204 to Suppress Head and Neck Tumor

    E-Print Network [OSTI]

    Gerstein, Mark

    Network Modeling Identifies Molecular Functions Targeted by miR-204 to Suppress Head and Neck Tumor targets predicted by sequence-alignment databases and the relative low accuracy of such predictions which with tumor progression in squamous cell carcinoma of the head and neck (HNSCC). We further demonstrate

  4. Corrosion mechanisms of low level vitrified radioactive waste in a loamy soil M.I. Ojovan1

    E-Print Network [OSTI]

    Sheffield, University of

    Corrosion mechanisms of low level vitrified radioactive waste in a loamy soil M.I. Ojovan1 , W-sodium content radioactive waste borosilicate glass buried in a loamy soil (glass K-26) and in an open testing. This mechanism is likely to remain dominant until the decay of 137 Cs in the glass is below exemption levels

  5. A trans-homologue interaction between reciprocally imprinted miR-127 and Rtl1 regulates placenta development

    E-Print Network [OSTI]

    Ito, Mitsuteru; Sferruzzi-Perri, Amanda N.; Edwards, Carol A.; Adalsteinsson, Bjorn T.; Allen, Sarah E.; Loo, Tsui-Han; Kitazawa, Moe; Kaneko-Ishino, Tomoko; Ishino, Fumitoshi; Stewart, Colin L.; Ferguson-Smith, Anne C.

    2015-07-02

    ability of small molecules like oxygen to transfer by passive diffusion from mother to fetus (Laga et al., 1973). The TDC and SDC values of the mutant placentae indicate that ?miR-127 mice have a higher diffusive capacity than WTs and conversely...

  6. THE DARK SIDE OF SECURITY BY OBSCURITY and Cloning MiFare Classic Rail and Building Passes, Anywhere, Anytime

    E-Print Network [OSTI]

    International Association for Cryptologic Research (IACR)

    , Anywhere, Anytime Nicolas T. Courtois University College London, Computer Science, Gower street, WC1E 6BT, London, UK Keywords: Access control, RFID, contactless smart cards, MiFare Classic, London Oyster card- wide and in public transportation. For more than 10 years the specification of these cards was kept

  7. A note on tsunami amplitudes above submarine slides and slumps M.I. Todorovska*, A. Hayir1

    E-Print Network [OSTI]

    Southern California, University of

    A note on tsunami amplitudes above submarine slides and slumps M.I. Todorovska*, A. Hayir1 , M 2531, Los Angeles, CA 90089-2531, USA Accepted 27 October 2001 Abstract Tsunami generated by submarine functions. Tsunami waveforms for these models are computed using linearized shallow water theory

  8. The PEANUT experiment in the NuMI beam at Fermilab

    SciTech Connect (OSTI)

    Russo, A. [Dipartimento di Scienze Fisiche, Universita Federico II di Napoli, 80125 Napoli (Italy)

    2010-03-30

    The PEANUT experiment was designed to study neutrino interactions in the few GeV range using the NuMI beam at Fermilab. The detector uses a hybrid technique, being made of nuclear emulsions and scintillator trackers. Emulsion films act as a tracking device and they are interleaved with lead plates used as neutrino targets. The detector is designed to reconstruct the topology of neutrino interactions at the single particle level. We present here the full reconstruction and analysis of a sample of 147 neutrino interactions that occurred in the PEANUT detector and the measurement of the quasielastic, resonance and deep-inelastic contributions to the total charged-current cross section. This technique could be applied for the beam monitoring at future neutrino facilities.

  9. Validation of the MCNPX-PoliMi Code to Design a Fast-Neutron Multiplicity Counter

    SciTech Connect (OSTI)

    J. L. Dolan; A. C. Kaplan; M. Flaska; S. A. Pozzi; D. L. Chichester

    2012-07-01

    Many safeguards measurement systems used at nuclear facilities, both domestically and internationally, rely on He-3 detectors and well established mathematical equations to interpret coincidence and multiplicity-type measurements for verifying quantities of special nuclear material. Due to resource shortages alternatives to these existing He-3 based systems are being sought. Work is also underway to broaden the capabilities of these types of measurement systems in order to improve current multiplicity analysis techniques. As a part of a Material Protection, Accounting, and Control Technology (MPACT) project within the U.S. Department of Energy's Fuel Cycle Technology Program we are designing a fast-neutron multiplicity counter with organic liquid scintillators to quantify important quantities such as plutonium mass. We are also examining the potential benefits of using fast-neutron detectors for multiplicity analysis of advanced fuels in comparison with He-3 detectors and testing the performance of such designs. The designs are being developed and optimized using the MCNPX-PoliMi transport code to study detector response. In the full paper, we will discuss validation measurements used to justify the use of the MCNPX-PoliMi code paired with the MPPost multiplicity routine to design a fast neutron multiplicity counter with liquid scintillators. This multiplicity counter will be designed with the end goal of safeguarding advanced nuclear fuels. With improved timing qualities associated with liquid scintillation detectors, we can design a system that is less limited by nuclear materials of high activities. Initial testing of the designed system with nuclear fuels will take place at Idaho National Laboratory in a later stage of this collaboration.

  10. T-1025 IU SciBath-768 detector tests in MI-12

    SciTech Connect (OSTI)

    Tayloe, Rex; Cooper, R.; Garrison, L.; Thornton, T.; Rebenitsch, L.; DeJongh, Fritz; Loer, Benjamin; Ramberg, Erik; Yoo, Jonghee; /Fermilab

    2012-02-11

    This is a memorandum of understanding between the Fermi National Accelerator Laboratory (Fermilab) and the experimenters of Department of Physics and Center for Exploration of Energy and Matter, Indiana University, who have committed to participate in detector tests to be carried out during the 2012 Fermilab Neutrino program. The memorandum is intended solely for the purpose of recording expectations for budget estimates and work allocations for Fermilab, the funding agencies and the participating institutions. it reflects an arrangement that currently is satisfactory to the parties; however, it is recognized and anticipated that changing circumstances of the evolving research program will necessitate revisions. The parties agree to modify this memorandum to reflect such required adjustments. Actual contractual obligations will be set forth in separate documents. The experimenters propsoe to test their prototype 'SciBat-768' detector in the MI-12 building for 3 months (February-April) in Spring 2012. The major goal of this effort is to measure or limit the flux of beam-induced neutrons in a far-off-axis (> 45{sup o}) location of the Booster Neutrino Beamline (BNB). This flux is of interest for a proposed coherent neutral-current neutrino-argon elastic scattering experiment. A second goal is to collect more test data for the SciBath-768 to enable better understanding and calibration of the device. The SciBath-768 detector successfully ran for 3 months in the MINOS Underground Area in Fall 2011 as testbeam experiment T-1014 and is currently running above ground in the MINOS service building. For the run proposed here, the experiments are requesting: space in MI-12 in which to run the SciBath detector during February-April 2012 while the BNB is operating; technical support to help with moving the equipment on site; access to power, internet, and accelerator signals; and a small office space from which to run and monitor the experiment.

  11. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    Office of Student Financial Aid The Welcome Center · 42 West Warren · P.O. Box 2340 · Detroit, MI. O. Box 2340 · 42 West Warren · Detroit, MI 48202-0340 2015-16 Verification of 2014 Income - Student · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne

  12. DOE - Office of Legacy Management -- Wyckoff Drawn Steel Co - IL 0-09

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouth DakotaRobbins and Myers Co -VANaval Ordnance - MI0-08

  13. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando n. 05/2011-Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    .04.2011 e del 19.04.2011; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia il bando pubblicato il 29 luglio 2011; VISTA la delibera del Consiglio di Dipartimento di Fisiologia dalla Commissione giudicatrice e conservati presso il Dipartimento di Fisiologia e Farmacologia DISPONE

  14. Bando n. 01/2012 del 24 luglio 2012 per il conferimento di incarico di professore straordinario con rapporto di lavoro a tempo determinato

    E-Print Network [OSTI]

    Di Pillo, Gianni

    rapporto di lavoro a tempo determinato APPROVAZIONE ATTI Il Direttore del Dipartimento di Fisiologia e convenzione, per il settore S/D BIO/14, settore concorsuale 05/G1 presso il Dipartimento di Fisiologia e Farmacologia; Vista la delibera del Consiglio di Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer

  15. Drill press "*il:J",,",,",tdont cone wrth bit stdAe? t(I

    E-Print Network [OSTI]

    Oh, Paul

    Drill press "*il:J",,",,",tdont cone wrth bit stdAe? t(I N'trkeyour own Ptrotng racK fron scrapwoodandPutdrill bits, sandingdrums' hole sawsand countersmKs right at your nnger- dps.Hete'show: drilling8 the desiSn of this laluable drill Press N'* II "MeetmY new butler '\\-clffFs rHE F^M|LY(^NDYMAN MAY

  16. BANDO N. D.D. 118/2010 PER IL RECLUTAMENTO DI UN RICERCATORE CON RAPPORTO DI LAVORO A TEMPO DETERMINATO CO FINANZIATO DALLA REGIONE LAZIO PER IL SETTORE S/D

    E-Print Network [OSTI]

    Di Pillo, Gianni

    caratterizzazione dei materiali per l'energia e l'ambiente. I suddetti requisiti devono essere posseduti alla data conversione di energia. Il ricercatore dovrà possedere competenze nelle procedure di sintesi e

  17. IL.26

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouth DakotaRobbins and700, 1.Reports1E~ S·D3GraniteS T A/ I'ixa6-q

  18. Prot. n. 943/2013 BANDO DI SELEZIONE PER IL CONFERIMENTO DI N. 1 ASSEGNO PER LO

    E-Print Network [OSTI]

    'Università degli Studi di Roma "La Sapienza". Il titolo del progetto di ricerca è: "Analisi di risposta sismica effetti del non sincronismo dell'azione sismica sulle costruzioni; livelli di conoscenza e fattori di

  19. Prot. n. 566/2014 BANDO DI SELEZIONE PER IL CONFERIMENTO DI N. 1 ASSEGNO PER LO

    E-Print Network [OSTI]

    Di Pillo, Gianni

    'Università degli Studi di Roma "La Sapienza". Il titolo del progetto di ricerca è: "Analisi di Risposta sismica effetti del non sincronismo dell'azione sismica sulle costruzioni; livelli di conoscenza e fattori di

  20. O RNL/TM -2000/152 Costs ofO ilD e pe nde nce

    E-Print Network [OSTI]

    O RNL/TM -2000/152 Costs ofO ilD e pe nde nce : A 2000 Update David L. Greene Oak Ridge National . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 2. COST COMPONENTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 2.2 MACROECONOMIC ADJUSTMENT COSTS . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 2

  1. Conserved Regulation of p53 Network Dosage by MicroRNA–125b Occurs through Evolving miRNA–Target Gene Pairs

    E-Print Network [OSTI]

    Le, Minh T. N.

    MicroRNAs regulate networks of genes to orchestrate cellular functions. MiR-125b, the vertebrate homologue of the Caenorhabditis elegans microRNA lin-4, has been implicated in the regulation of neural and hematopoietic ...

  2. {00012119.DOC /} Graduate Medical Education 540 E. Canfield Detroit, MI 48201 Phone 313-577-5189 Fax 313-577-5245

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    {00012119.DOC /} Graduate Medical Education 540 E. Canfield · Detroit, MI 48201 · Phone 313; This agreement of appointment by and between WSU, whose address is 540 East Canfield, Detroit, Michigan 48201

  3. ANRV253-MI59-05 ARI 21 April 2005 18:7 Diversity and Evolution of

    E-Print Network [OSTI]

    Plotkin, Joshua B.

    ANRV253-MI59-05 ARI 21 April 2005 18:7 R E V I E W S IN A D V A N CE Diversity and Evolution: pohlschr@sas.upenn.edu, njhand@sas.upenn.edu, kdilks@sas.upenn.edu, alexh@sas.upenn.edu 2 University of L. Rev. Microbiol. 2005. 59:91­111 doi: 10.1146/ annurev.micro.59.030804.121353 Copyright c 2005

  4. SU-E-J-121: Measuring Prompt Gamma Emission Profiles with a Multi...

    Office of Scientific and Technical Information (OSTI)

    MD (United States) University of Michigan, Ann Arbor, MI (United States) MD Anderson Cancer Center, Houston, TX (United States) Procure Proton Therapy Center, Oklahoma City, OK...

  5. "Title","Creator/Author","Publication Date","OSTI Identifier...

    Office of Scientific and Technical Information (OSTI)

    of Michigan, Ann Arbor, MI (United States); Mackin, D; Beddar, S MD Anderson Cancer Center, Houston, TX (United States); Zheng, Y Procure Proton Therapy Center,...

  6. SU-E-J-121: Measuring Prompt Gamma Emission Profiles with a Multi...

    Office of Scientific and Technical Information (OSTI)

    of Michigan, Ann Arbor, MI (United States); Mackin, D; Beddar, S MD Anderson Cancer Center, Houston, TX (United States); Zheng, Y Procure Proton Therapy Center,...

  7. Myc induced miR-144/451 contributes to the acquired imatinib resistance in chronic myelogenous leukemia cell K562

    SciTech Connect (OSTI)

    Liu, Li, E-mail: liuli029@yahoo.cn [Department of Hematology, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038 (China)] [Department of Hematology, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038 (China); Wang, Sitao; Chen, Renan; Wu, Yanlan; Zhang, Bei; Huang, Siyong; Zhang, Jingyi; Xiao, Fang; Wang, Meng; Liang, Yingmin [Department of Hematology, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038 (China)] [Department of Hematology, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038 (China)

    2012-08-24

    Highlights: Black-Right-Pointing-Pointer Increased c-myc expression in imatinib resistant CML cells. Black-Right-Pointing-Pointer c-myc contributes the imatinib resistance in CML cells. Black-Right-Pointing-Pointer c-myc transcriptionally reduces the expression of miR-144/451 in K562R cells. Black-Right-Pointing-Pointer Restoration of miR-144/451 reverses the resistance of K562R cells to imatinib. -- Abstract: Imatinib resistance remains the big hurdle for CML therapy. Previous study reveals that c-myc is important for bcr-abl CML cell proliferation, while its role in imatinib resistance is largely unknown. In this study, we first found that c-myc expression is upregulated in imatinib resistant K562R cells, which in turn enhances the expression of miR-144/451. Knockdown of c-myc or restoration of miR-144/451 in the K562R cells sensitizes K562R cells to imatinib therapy. Our study here reveals an regulatory pathway between myc and miR-144/451 and highlights that targeting either myc or miR-144/451 might be valuable for eliminating the imatinib resistant CML cells.

  8. DOE - Office of Legacy Management -- Eimco Corp - IL 0-01

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouth Dakota Edgemont, SouthLaboratoryDiv - NYCorp - NJEimco Corp - IL

  9. DOE - Office of Legacy Management -- Hydroblast Corp - IL 0-03

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouth Dakota Edgemont, SouthLaboratoryDivHarshawHydroblast Corp - IL

  10. File:USDA-CE-Production-GIFmaps-IL.pdf | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QAsource History View New Pages RecentTempCampApplicationWorksheet 2011.pdf JumpTransmission SitingFL.pdfIL.pdf Jump

  11. Mitsubishi iMiEV: An Electric Mini-Car in NREL's Advanced Technology Vehicle Fleet (Fact Sheet)

    SciTech Connect (OSTI)

    Not Available

    2011-10-01

    This fact sheet highlights the Mitsubishi iMiEV, an electric mini-car in the advanced technology vehicle fleet at the National Renewable Energy Laboratory (NREL). In support of the U.S. Department of Energy's fast-charging research efforts, NREL engineers are conducting charge and discharge performance testing on the vehicle. NREL's advanced technology vehicle fleet features promising technologies to increase efficiency and reduce emissions without sacrificing safety or comfort. The fleet serves as a technology showcase, helping visitors learn about innovative vehicles that are available today or are in development. Vehicles in the fleet are representative of current, advanced, prototype, and emerging technologies.

  12. Algebra (Informatica) 9 gennaio 2003 Con pi di 18 punti si pu fare l'orale o accettare il voto dello scritto (30 e lode per chi

    E-Print Network [OSTI]

    Catenacci, Roberto

    Algebra (Informatica) ­ 9 gennaio 2003 Con più di 18 punti si può fare l'orale o accettare il voto

  13. BANDO DI SELEZIONE PER IL CONFERIMENTO DI n. 1 ASSEGNO PER LO SVOLGIMENTO DI ATTIVIT DI RICERCA -CATEGORIA B TIPOLOGIA I

    E-Print Network [OSTI]

    Di Pillo, Gianni

    a disfunzione cerebrale, psicopatologia e risposta ai trattamenti"- Responsabile Prof. Giuseppe a disfunzione cerebrale, psicopatologia e risposta ai trattamenti" presso il Dipartimento di Scienze

  14. Il teatro come denuncia e strumento di espressione del popolo: " I Dialoghi" di Ruzzante e "Morte accidentale di un anarchico" di Dario Fo

    E-Print Network [OSTI]

    Zamboni, Camilla

    2011-01-01

    cancaro, la sarae stà da riso, s’a’i ligava! 20 [RUZANTE –afferma Fo, “la beffa, il riso, fanno capire molto meglio

  15. Miniature lightweight x-ray optics (MiXO) for surface elemental composition mapping of asteroids and comets

    E-Print Network [OSTI]

    Hong, Jaesub

    2016-01-01

    The compositions of diverse planetary bodies are of fundamental interest to planetary science, providing clues to the formation and evolutionary history of the target bodies and the Solar system as a whole. Utilizing the X-ray fluorescence unique to each atomic element, X-ray imaging spectroscopy is a powerful diagnostic tool of the chemical and mineralogical compositions of diverse planetary bodies. Until now the mass and volume of focusing X-ray optics have been too large for resource-limited in-situ missions, so near-target X-ray observations of planetary bodies have been limited to simple collimator-type X-ray instruments. We introduce a new Miniature lightweight Wolter-I focusing X-ray Optics (MiXO) using metal-ceramic hybrid X-ray mirrors based on electroformed nickel replication and plasma thermal spray processes. MiXO can enable compact, powerful imaging X-ray telescopes suitable for future planetary missions. We illustrate the need for focusing X-ray optics in observing relatively small planetary bod...

  16. IL NUOVO CIMENTO VoL. XXXVI, N. 3 1o Aprlle 1965 Further Analysis of ~.-C~2 Scattering Process

    E-Print Network [OSTI]

    Bertero, Mario

    , instead-of analysing the real cross-section: (1) (where ~(0) = ~ - i ~ eosec~ 12 + ~ (2~ + 1) .P~(cos O ~-particles~ and 0 the c.m. scattering angle), the fictitious one given by 1 was analysed. This is the cross-sectionIL NUOVO CIMENTO VoL. XXXVI, N. 3 1o Aprlle 1965 Further Analysis of ~.-C~2 Scattering Process

  17. INNOVAZIONE E TRASFERIMENTO TECNOLOGICO Il 2006 ha visto una ridefinizione strategica e un potenziamento di obiettivi, strumenti, attivit e

    E-Print Network [OSTI]

    De Cindio, Fiorella

    secondo tre assi principali: Asse 1 Realizzare il trasferimento e valorizzare economicamente i trovati e sovrintendono all'istruttoria delle iniziative. Asse 2 Stabilire relazioni con le realtà esterne, promuovendo progetti e conoscenze. Asse 3 Promuovere la capacità di sviluppare una conoscenza e una capacità

  18. BANDO N. 1-2012 PER IL CONFERIMENTO DI INCARICO DI PROFESSORE STRAORDINARIO CON RAPPORTO DI LAVORO A TEMPO DETERMINATO

    E-Print Network [OSTI]

    Di Pillo, Gianni

    A TEMPO DETERMINATO Il Direttore del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" Vista Rettorale n. 220 del 4.2.2011 Viste le delibere del Consiglio del Dipartimento di Fisiologia e Farmacologia Dipartimento di Fisiologia e Farmacologia e la società Duemme Trust Company s.r.l. in data 14.05.2012 nella

  19. Bando n. 03_2012 AVVISO PUBBLICO DI SELEZIONE PER IL CONFERIMENTO DI N. 2 INCARICHI DI

    E-Print Network [OSTI]

    Di Pillo, Gianni

    DIPARTIMENTO DI FISIOLOGIA E FARMACOLOGIA "VITTORIO ERSPAMER" VISTO - Visto il Regolamento per l'affidamento di rappresentate dal Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer"; - Ravvisata conseguentemente la all'art. 1 del presente avviso a favore del Dipartimento di Fisiologia e Farmacologia "Vittorio

  20. BANDO DI SELEZIONE PER IL CONFERIMENTO DI ASSEGNI PER LO SVOLGIMENTO DI ATTIVIT DI RICERCA DI CATEGORIA B)

    E-Print Network [OSTI]

    Di Pillo, Gianni

    , rispettivamente del 12.04.2011 e del 19.04.2011; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e scientifico disciplinare BIO 09, presso il Dipartimento di #12;Fisiologia e Farmacologia "Vittorio Erspamer del titolo di dottore di ricerca in Fisiologia [Physiology] o Psicobiologia e psicologia fisiologica

  1. Bando n. 01/2010 del 10 marzo 2010 per il reclutamento di un Ricercatore a Tempo Determinato APPROVAZIONE ATTI

    E-Print Network [OSTI]

    Di Pillo, Gianni

    APPROVAZIONE ATTI Il Direttore del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" VISTO l'art. 7 Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" e la Fondazione "Enrico ed Enrica Sovena", con e loro costituenti chimici"; VISTA la Delibera del Consiglio del Dipartimento di Fisiologia e

  2. Genome-wide scan reveals association of psoriasis with IL-23 and NF-kB pathways

    E-Print Network [OSTI]

    Abecasis, Goncalo

    Genome-wide scan reveals association of psoriasis with IL-23 and NF-kB pathways Rajan P Nair1 Abecasis4,20, for the Collaborative Association Study of Psoriasis18 Psoriasis is a common immune-mediated disorder that affects the skin, nails and joints. To identify psoriasis susceptibility loci, we genotyped

  3. INCT FOR CLIMATE CHANGE | 2009.2010 | ACTIVITY REPORT | BRAzIL National Institute of Science and

    E-Print Network [OSTI]

    1 INCT FOR CLIMATE CHANGE | 2009.2010 | ACTIVITY REPORT | BRAzIL National Institute of Science and Technology for Climate Change December 2010 ISSN 2179-5754 #12;2 Overall coordination Carlos Programa FAPESP de Pesquisa sobre Mudanças Climáticas Globais Executive Board of INCT for Climate Change

  4. Les hpitaux sont-ils des organisations haute fiabilit ? Apports du concept de HRO la GRH des

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    réalisés auprès du personnel soignant de 4 centres hospitaliers de la région parisienne. Cet article entretien réalisé dans une seconde collecte de données. Il apparaît que le domaine hospitalier génère des la GRH " Vers un management des ressources humaines durable et bienveillant ?, Marrakech : France

  5. Received 2 Oct 2014 | Accepted 2 Feb 2015 | Published 12 Mar 2015 IL-23-mediated mononuclear phagocyte crosstalk

    E-Print Network [OSTI]

    ARTICLE Received 2 Oct 2014 | Accepted 2 Feb 2015 | Published 12 Mar 2015 IL-23-mediated mononuclear phagocyte crosstalk protects mice from Citrobacter rodentium-induced colon immunopathology Tegest that colonic CX3CR1þ mononuclear phagocytes are critical inducers of the innate response to Citrobacter

  6. 2013 Il Monito del Giardino Aaron Wolf, a geography professor in OSU's College of Earth, Ocean, and

    E-Print Network [OSTI]

    Kurapov, Alexander

    2013 Il Monito del Giardino Aaron Wolf, a geography professor in OSU's College of Earth, Ocean. Wolf took his MS in Water Resources (1990) and Ph.D. in Land Resources (1992) from University of Wisconsin, Madison. Aaron Wolf Professor, Geography "It is a real honor to have this work being recognized

  7. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando AR N. 04/2014 del 15/04/2014 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    .04.2011 e del 19.04.2011; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia conservati presso il Dipartimento di Fisiologia e Farmacologia DISPONE Art.1 ­ Sono approvati gli atti della I), presso il Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" di questa Università per

  8. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando n. 01/2014 dell'11/02/2014 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    Civitavecchia e destinata ad assegni di ricerca; VISTA la delibera del Consiglio del Dipartimento di Fisiologia; VISTI i verbali redatti dalla Commissione giudicatrice e conservati presso il Dipartimento di Fisiologia Fisiologia e Farmacologia "Vittorio Erspamer" di questa Università per il settore scientifico disciplinare

  9. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando AR N. 05/2014 del 26/06/2014 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    .04.2011 e del 19.04.2011; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia conservati presso il Dipartimento di Fisiologia e Farmacologia DISPONE Art.1 ­ Sono approvati gli atti della II), presso il Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" di questa Università per

  10. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando AR N. 06/2014 del 25/07/2014 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    .04.2011 e del 19.04.2011; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia verbali redatti dalla Commissione giudicatrice e conservati presso il Dipartimento di Fisiologia e di ricerca annuale, rinnovabile, categoria B) tipologia I), presso il Dipartimento di Fisiologia e

  11. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando n. 10/2011-Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 23 settembre bando pubblicato il 28 settembre 2011; VISTA la delibera del Consiglio di Dipartimento di Fisiologia e giudicatrice e conservati presso il Dipartimento di Fisiologia e Farmacologia DISPONE Art.1 ­ Sono approvati

  12. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando n. 01/2013 del 17 gennaio 2013 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    .04.2011; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 16 pubblicato il 17 gennaio 2013; VISTA la delibera del Consiglio di Dipartimento di Fisiologia e Farmacologia presso il Dipartimento di Fisiologia e Farmacologia DISPONE Art.1 ­ Sono approvati gli atti della

  13. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando n. 12/2011-Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 20 ottobre il 24 ottobre 2011; VISTA la delibera del Consiglio di Dipartimento di Fisiologia e Farmacologia presso il Dipartimento di Fisiologia e Farmacologia DISPONE Art.1 ­ Sono approvati gli atti della

  14. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando AR N. 02/2014 del 14/02/2014 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    Consiglio del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 18 dicembre 2013 nella quale Fisiologia e Farmacologia DISPONE Art.1 ­ Sono approvati gli atti della selezione pubblica per il di Fisiologia e Farmacologia "Vittorio Erspamer" di questa Università per il settore scientifico

  15. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando AR N. 08/2014 del 17/09/2014 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    .04.2011 e del 19.04.2011; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia giudicatrice e conservati presso il Dipartimento di Fisiologia e Farmacologia DISPONE Art.1 ­ Sono approvati, categoria B) tipologia I), presso il Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" di questa

  16. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando AR N. 10/2014 del 26/11/2014 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    .04.2011 e del 19.04.2011; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia conservati presso il Dipartimento di Fisiologia e Farmacologia DISPONE Art.1 ­ Sono approvati gli atti della I), presso il Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" di questa Università per

  17. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando n. 05/2013 del 29 luglio 2013 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    .04.2011; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 26 conservati presso il Dipartimento di Fisiologia e Farmacologia DISPONE Art.1 ­ Sono approvati gli atti della II), presso il Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" di questa Università per

  18. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando AR N. 11/2014 del 28/11/2014 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    .04.2011 e del 19.04.2011; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia dalla Commissione giudicatrice e conservati presso il Dipartimento di Fisiologia e Farmacologia DISPONE annuale, rinnovabile, categoria B) tipologia II), presso il Dipartimento di Fisiologia e Farmacologia

  19. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando AR N. 07/2014 del 25/07/2014 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    .04.2011 e del 19.04.2011; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia verbali redatti dalla Commissione giudicatrice e conservati presso il Dipartimento di Fisiologia e di ricerca annuale, rinnovabile, categoria B) tipologia I), presso il Dipartimento di Fisiologia e

  20. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando n. 02/2011 del 4 aprile 2011 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    . n. 21702; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia "Vittorio Commissione giudicatrice e conservati presso il Dipartimento di Fisiologia e Farmacologia DISPONE Art.1 ­ Sono, rinnovabile, categoria B) tipologia II), presso il Dipartimento di Fisiologia e Farmacologia "Vittorio

  1. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando n. 10/2013 del 20/12/2013 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    , rispettivamente del 12.04.2011 e del 19.04.2011; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e; VISTI i verbali redatti dalla Commissione giudicatrice e conservati presso il Dipartimento di Fisiologia Fisiologia e Farmacologia "Vittorio Erspamer" di questa Università per il settore scientifico disciplinare

  2. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando AR N. 09/2014 del 17/09/2014 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    .04.2011 e del 19.04.2011; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia verbali redatti dalla Commissione giudicatrice e conservati presso il Dipartimento di Fisiologia e di ricerca annuale, rinnovabile, categoria B) tipologia II), presso il Dipartimento di Fisiologia e

  3. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando n. 07/2013 del 14 ottobre 2013 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    .04.2011; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 27 conservati presso il Dipartimento di Fisiologia e Farmacologia DISPONE Art.1 ­ Sono approvati gli atti della II), presso il Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" di questa Università per

  4. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando AR N. 03/2014 del 15/04/2014 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    .04.2011 e del 19.04.2011; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia conservati presso il Dipartimento di Fisiologia e Farmacologia DISPONE Art.1 ­ Sono approvati gli atti della I), presso il Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" di questa Università per

  5. VISTO il D.P.R. n. 371 del 4 marzo 1982; VISTI i Decreti del Ministro dell'Universit e della Ricerca Scientifica e

    E-Print Network [OSTI]

    Milano-Bicocca, Università

    'amministrazione, la finanza e la contabilità emanato con D.R. n. 3671 del 4 marzo 2002 registrato in pari data; VISTA elementi: - il codice e la denominazione del centro di costo; - il Consegnatario; - la data di arrivo dei costo non dotati di autonomia contabile e finanziaria propria (Istituti, Facoltà, Centri, Biblioteca e

  6. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne Center · P. O. Box 2340 · 42 West Warren · Detroit, MI 48202-0340 3/2015 Student's First Name 9-digit WSU

  7. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne · The Welcome Center · P. O. Box 2340 · 42 West Warren · Detroit, MI 48202-0340 3/2015 Student's First Name 9

  8. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    Office of Student Financial Aid The Welcome Center · 42 West Warren · P.O. Box 2340 · Detroit, MI.O. Box 2340 · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · www

  9. Expression of low-, intermediate-, and high-affinity IL-2 receptors on B cell lines derived from patients with undifferentiated lymphoma of Burkitt's and non-Burkitt's types

    SciTech Connect (OSTI)

    Benjamin, D.; Rosolen, A.; Wormsley, S.B.; DeBault, L.E.; Colamonici, O.R. )

    1990-08-01

    IL-2 receptors on T cells exist in at least three forms which differ in their ligand-binding affinity. The low-affinity IL-2 receptor (IL-2R) consists of the 55-kDa Tac protein (p55 alpha), the intermediate-affinity site corresponds to the 70-kDa molecule (p70 beta), and the high-affinity IL-2R consists of a noncovalent heterodimeric structure involving both p55 alpha and p70 beta. We studied 24 B cell lines (8 EBV-negative and 16 EBV-positive) for IL-2R expression in the presence or absence of the tumor promoter, teleocidin. 125I-IL-2 radioreceptor binding assays and crosslinking studies demonstrated the sole expression of p55 alpha in EBV-negative cell lines only, whereas p55 alpha present in EBV-positive cell lines was always associated with p70 beta to construct high-affinity IL-2R. p70 beta was not detected in any of the EBV-negative cell lines, but was expressed on most of the EBV-positive cell lines (13 of 16). Our data also indicate that the expression of p55 alpha and p70 beta by radiolabeling correlates with their expression in flow cytometry, and that a large excess of p55 alpha is required to construct high-affinity IL-2R. Coexpression of p55 alpha and p70 beta on human B cells contributed to constructing high-affinity IL-2R hybrid complex as shown by rapid association rate contributed by p55 alpha and slow dissociation rate by p70 beta; teleocidin's ability to induce p55 alpha on cell lines which express p70 beta only, resulting in appearance of high-affinity IL-2R; and blocking p55 alpha by anti-Tac mAb in cell lines which constitutively express high-affinity IL-2R eliminated both high- and low-affinity components. The existence of low, intermediate, and high IL-2R on human B cells bears important future implications for understanding the mechanism of IL-2 signaling and the role of IL-2 in B cell activation, proliferation, and differentiation.

  10. IL1{beta}-mediated Stromal COX-2 signaling mediates proliferation and invasiveness of colonic epithelial cancer cells

    SciTech Connect (OSTI)

    Zhu, Yingting; Tissue Tech Inc, Miami, FL 33173 ; Zhu, Min; Lance, Peter

    2012-11-15

    COX-2 is a major inflammatory mediator implicated in colorectal inflammation and cancer. However, the exact origin and role of COX-2 on colorectal inflammation and carcinogenesis are still not well defined. Recently, we reported that COX-2 and iNOS signalings interact in colonic CCD18Co fibroblasts. In this article, we investigated whether activation of COX-2 signaling by IL1{beta} in primary colonic fibroblasts obtained from normal and cancer patients play a critical role in regulation of proliferation and invasiveness of human colonic epithelial cancer cells. Our results demonstrated that COX-2 level was significantly higher in cancer associated fibroblasts than that in normal fibroblasts with or without stimulation of IL-1{beta}, a powerful stimulator of COX-2. Using in vitro assays for estimating proliferative and invasive potential, we discovered that the proliferation and invasiveness of the epithelial cancer cells were much greater when the cells were co-cultured with cancer associated fibroblasts than with normal fibroblasts, with or without stimulation of IL1{beta}. Further analysis indicated that the major COX-2 product, prostaglandin E{sub 2}, directly enhanced proliferation and invasiveness of the epithelial cancer cells in the absence of fibroblasts. Moreover, a selective COX-2 inhibitor, NS-398, blocked the proliferative and invasive effect of both normal and cancer associate fibroblasts on the epithelial cancer cells, with or without stimulation of IL-1{beta}. Those results indicate that activation of COX-2 signaling in the fibroblasts plays a major role in promoting proliferation and invasiveness of the epithelial cancer cells. In this process, PKC is involved in the activation of COX-2 signaling induced by IL-1{beta} in the fibroblasts.

  11. Eu3+ as a dual probe for the determination of IL anion donor power: A combined luminescence spectroscopic and electrochemical approach

    SciTech Connect (OSTI)

    Babai, Arash; Kopiec, Gabriel; Lackmann, Anastasia; Mallick, Bert; Pitula, Slawomir; Tang, Sifu; Mudring, Anja-Verena

    2014-04-01

    This work is aimed at giving proof that Eu(Tf2N)(3) (Tf2N = bis(trifluoromethanesulfonyl)amide) can act as both an optical and electrochemical probe for the determination of the Lewis acidity of an ionic liquid anion. For that reason the luminescence spectra and cyclic voltammograms of dilute solutions of Eu(Tf2N)(3) in various ionic liquids were investigated. The Eu2+/3+ redox potential in the investigated ILs can be related to the Lewis basicity of the IL anion. The IL cation had little influence. The lower the determined halfwave potential, the higher the IL anion basicity. The obtained ranking can be confirmed by luminescence spectroscopy where a bathochromic shift of the D-5(0) -> F-7(4) transition indicates a stronger Lewis basicity of the IL anion. (C) 2014 Published by Elsevier B.V.

  12. Structure of the unique SEFIR domain from human interleukin 17 receptor A reveals a composite ligand-binding site containing a conserved ?-helix for Act1 binding and IL-17 signaling

    SciTech Connect (OSTI)

    Zhang, Bing [Oklahoma State University, Stillwater, OK 74078 (United States); Liu, Caini; Qian, Wen [Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195 (United States); Han, Yue [Oklahoma State University, Stillwater, OK 74078 (United States); Li, Xiaoxia, E-mail: lix@ccf.org [Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195 (United States); Deng, Junpeng, E-mail: lix@ccf.org [Oklahoma State University, Stillwater, OK 74078 (United States)

    2014-05-01

    Crystal structure of the SEFIR domain from human IL-17 receptor A provides new insights into IL-17 signaling. Interleukin 17 (IL-17) cytokines play a crucial role in mediating inflammatory and autoimmune diseases. A unique intracellular signaling domain termed SEFIR is found within all IL-17 receptors (IL-17Rs) as well as the key adaptor protein Act1. SEFIR-mediated protein–protein interaction is a crucial step in IL-17 cytokine signaling. Here, the 2.3 Å resolution crystal structure of the SEFIR domain of IL-17RA, the most commonly shared receptor for IL-17 cytokine signaling, is reported. The structure includes the complete SEFIR domain and an additional ?-helical C-terminal extension, which pack tightly together to form a compact unit. Structural comparison between the SEFIR domains of IL-17RA and IL-17RB reveals substantial differences in protein topology and folding. The uniquely long insertion between strand ?C and helix ?C in IL-17RA SEFIR is mostly well ordered, displaying a helix (?CC?{sub ins}) and a flexible loop (CC?). The DD? loop in the IL-17RA SEFIR structure is much shorter; it rotates nearly 90° with respect to the counterpart in the IL-17RB SEFIR structure and shifts about 12 Å to accommodate the ?CC?{sub ins} helix without forming any knots. Helix ?C was identified as critical for its interaction with Act1 and IL-17-stimulated gene expression. The data suggest that the heterotypic SEFIR–SEFIR association via helix ?C is a conserved and signature mechanism specific for IL-17 signaling. The structure also suggests that the downstream motif of IL-17RA SEFIR together with helix ?C could provide a composite ligand-binding surface for recruiting Act1 during IL-17 signaling.

  13. Michigan State University | College of Engineering | Engineering Undergraduate Studies 1410 Engineering Building, East Lansing, MI 48824-1226 | (517) 355-6616 ext. 1

    E-Print Network [OSTI]

    (30) CEM 141 General Chemistry 4 EGR 100 Introduction to Engineering Design 2 EGR 102 IntroductionMichigan State University | College of Engineering | Engineering Undergraduate Studies 1410 Engineering Building, East Lansing, MI 48824-1226 | (517) 355-6616 ext. 1 http

  14. 50,000-Watt AM Stations IA | MB | MI | MN | NE | ND | ON | SD | WI | Station News | Owners | TV Captures | Links

    E-Print Network [OSTI]

    Allen, Gale

    that broadcast with a power of 50,000 Watts day and night. Some of these stations are what was once known50,000-Watt AM Stations IA | MB | MI | MN | NE | ND | ON | SD | WI | Station News | Owners | TV Captures | Links 50,000-Watt AM stations This list includes AM stations in the United States and Canada

  15. Michigan State University | College of Engineering | Engineering Undergraduate Studies Engineering Building, 428 S. Shaw Lane, Room 1415, East Lansing MI 48824 | (517) 355-6616 ext. 1

    E-Print Network [OSTI]

    Feeny, Brian

    Building, 428 S. Shaw Lane, Room 1415, East Lansing MI 48824 | (517) 355-6616 ext. 1 http 132 Calculus I 3 MTH 133 Calculus II 4 MTH 234 Multivariable Calculus 4 MTH 235 Differential Equations Energy Systems 3 ME 422 Introduction to Combustion 3 ME 423 Intermed Mech of Deformable Solids 3 ME 425

  16. Michigan State University | College of Engineering | Engineering Undergraduate Studies Engineering Building, 428 S. Shaw Lane, Room 1415, East Lansing MI 48824 | (517) 355-6616 ext. 1

    E-Print Network [OSTI]

    Building, 428 S. Shaw Lane, Room 1415, East Lansing MI 48824 | (517) 355-6616 ext. 1 http 234 Multivariable Calculus 4 MTH 235 Differential Equations 3 PHY 183 Physics for Scientists 450 International Environmental Law & Policy 3 ME 417 Design of Alternative Energy Systems 3 ME 422

  17. Michigan State University | College of Engineering | Engineering Undergraduate Studies Engineering Building, 428 S. Shaw Lane, Room 1415, East Lansing MI 48824 | (517) 355-6616 ext. 1

    E-Print Network [OSTI]

    Building, 428 S. Shaw Lane, Room 1415, East Lansing MI 48824 | (517) 355-6616 ext. 1 http to Engineering Modeling 2 MTH 132 Calculus I 3 MTH 133 Calculus II 4 MTH 234 Multivariable Calculus 4 MTH 235 4 CEM 161 Chemistry Laboratory I 1 CHE 201 Materials and Energy Balances 3 ENE 280 Principles

  18. Evaluation of Multiplexed 16S rRNA Microbial Population Surveys Using Illumina MiSeq Platform (Seventh Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting 2012)

    ScienceCinema (OSTI)

    Tremblay, Julien [DOE JGI

    2013-01-25

    Julien Tremblay from DOE JGI presents "Evaluation of Multiplexed 16S rRNA Microbial Population Surveys Using Illumina MiSeq Platorm" at the 7th Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting held in June, 2012 in Santa Fe, NM.

  19. Society of Automotive Engineers (SAE) Technical Paper 2006-01-1041 Paper presented at SAE 2006 World Congress & Exposition, April 5, 2006, Detroit, MI

    E-Print Network [OSTI]

    Gruner, Sol M.

    Society of Automotive Engineers (SAE) Technical Paper 2006-01-1041 Paper presented at SAE 2006 and Fundamental Advances in Thermal Fluid Sciences 2006. Vol. SP-2015. (Society of Automotive Engineers, Troy, MI and reducing emissions play an essential role in the design of the new-generation automotive internal

  20. Evaluation of Multiplexed 16S rRNA Microbial Population Surveys Using Illumina MiSeq Platform (Seventh Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting 2012)

    SciTech Connect (OSTI)

    Tremblay, Julien [DOE JGI] [DOE JGI

    2012-06-01

    Julien Tremblay from DOE JGI presents "Evaluation of Multiplexed 16S rRNA Microbial Population Surveys Using Illumina MiSeq Platorm" at the 7th Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting held in June, 2012 in Santa Fe, NM.

  1. The ArgoNeuT Detector in the NuMI Low-Energy beam line at Fermilab

    E-Print Network [OSTI]

    C. Anderson; M. Antonello; B. Baller; T. Bolton; C. Bromberg; F. Cavanna; E. Church; D. Edmunds; A. Ereditato; S. Farooq; B. Fleming; H. Greenlee; R. Guenette; S. Haug; G. Horton-Smith; C. James; E. Klein; K. Lang; A. Lathrop; P. Laurens; S. Linden; D. McKee; R. Mehdiyev; B. Page; O. Palamara; K. Partyka; S. Pordes; G. Rameika; B. Rebel; B. Rossi; R. Sanders; M. Soderberg; J. Spitz; A. M. Szelc; M. Weber; T. Yang; T. Wongjirad; G. Zeller

    2012-06-05

    The ArgoNeuT liquid argon time projection chamber has collected thousands of neutrino and antineutrino events during an extended run period in the NuMI beam-line at Fermilab. This paper focuses on the main aspects of the detector layout and related technical features, including the cryogenic equipment, time projection chamber, read-out electronics, and off-line data treatment. The detector commissioning phase, physics run, and first neutrino event displays are also reported. The characterization of the main working parameters of the detector during data-taking, the ionization electron drift velocity and lifetime in liquid argon, as obtained from through-going muon data complete the present report.

  2. A library of MiMICs allows tagging of genes and reversible, spatial and temporal knockdown of proteins in Drosophila

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Nagarkar-Jaiswal, Sonal; Lee, Pei-Tseng; Campbell, Megan E.; Chen, Kuchuan; Anguiano-Zarate, Stephanie; Cantu Gutierrez, Manuel; Busby, Theodore; Lin, Wen-Wen; He, Yuchun; Schulze, Karen L.; et al

    2015-03-31

    Here, we document a collection of ~7434 MiMIC (Minos Mediated Integration Cassette) insertions of which 2854 are inserted in coding introns. They allowed us to create a library of 400 GFP-tagged genes. We show that 72% of internally tagged proteins are functional, and that more than 90% can be imaged in unfixed tissues. Moreover, the tagged mRNAs can be knocked down by RNAi against GFP (iGFPi), and the tagged proteins can be efficiently knocked down by deGradFP technology. The phenotypes associated with RNA and protein knockdown typically correspond to severe loss of function or null mutant phenotypes. Finally, we demonstratemore »reversible, spatial, and temporal knockdown of tagged proteins in larvae and adult flies. This new strategy and collection of strains allows unprecedented in vivo manipulations in flies for many genes. These strategies will likely extend to vertebrates.« less

  3. Better Buildings Workforce Peer Exchange and Green for All High...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Participating Programs * Austin, TX * West Babylon, NY (Long Island Green Homes) * Baltimore, MD * Chicago, IL * Cincinnati, OH * St. Lucie County, FL * Kansas City, MO *...

  4. Better Buildings Neighborhood Program Multi-family/Low Income...

    Energy Savers [EERE]

    Programs and Organizations * Austin, TX * Bainbridge Island, WA * Chicago, IL * Connecticut * Eagle County, CO * Kansas City, MO * Lincoln, Nebraska * New York * Phoenix, AZ *...

  5. Other Participants 1992 | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    , Lubbock , TX Lyons Township High School , La Grange , IL Mississippi School for Math & Science, Columbus , MS Newnan High School , Newnan , GA Pembroke Hill High School ,...

  6. LUBBOCK, TX (KCBD) -WE RECOMMEND

    E-Print Network [OSTI]

    Rock, Chris

    McBride Killed Seeking Help After Accident (Essence) Will the oil & gas boom reach Lubbock? Posted Midland's economy has seen big benefits from their oil and gas boom. Could the same thing happen in Lubbock? On Friday, the Lubbock Economic Development Alliance hosted a luncheon exploring

  7. ~txF74.ptx

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobsMotion toCoal_Budget_Fact_Sheet.pdf More Documents &ER-B-00-03 + +

  8. ~tx22C0.ptx

    Energy Savers [EERE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION J APPENDIX E LIST OFAMERICA'S FUTURE.EnergyWoodenDate Rec TypeFutureGen_Fact_Sheet.pdf-234-4433

  9. US WSC TX Site Consumption

    Gasoline and Diesel Fuel Update (EIA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustments (Billion Cubic Feet) Wyoming963 1.969 1.979Coal Consumers inYear JanSales Type: Sales120NE MASoAtlWSC

  10. Il Dipartimento di Architettura e Progetto DiAP della Sapienza organizza un Workshop di progettazione riservato agli studenti e ai dottorandi delle facolt di architettura e di inge-

    E-Print Network [OSTI]

    Di Pillo, Gianni

    "Summer Field Studio 2011 in Teheran" è la ristruttu- razione di un'area urbana di Teheran, il quartiere

  11. Instructions for use Dielectric spectroscopy study on ionic liquid microemulsion composed of

    E-Print Network [OSTI]

    Tsunogai, Urumu

    and the versatility of mi- croemulsion. In addition to the "green solvents" nature, ILs are also known as "designer

  12. ProjectRanking(Economic) District Potentially Impacted USACE Navigation Projects

    E-Print Network [OSTI]

    US Army Corps of Engineers

    (0045009) IL 2 X X 102 Detroit DETROIT RIVER MICHIGAN (0004710) MI 1 X 137 Detroit ST. CLAIR RIVER MICHIGAN

  13. IL-2R{gamma} gene microdeletion demonstrates that canine X-linked severe combined immunodeficiency is a homologue of the human disease

    SciTech Connect (OSTI)

    Henthorn, P.S.; Fimiani, V.M.; Patterson, D.F.

    1994-09-01

    X-linked severe combined immunodeficiency (SCID) is characterized by profound defects in cellular and humoral immunity and, in humans, is associated with mutations in the gene for the {gamma} chain of the IL-2 receptor (IL-2R{gamma}). We have examined this gene in a colony of dogs established from a single X-linked SCID carrier female. Affected dogs have a 4-bp deletion in the first exon of the IL-2R{gamma} gene, which precludes the production of a functional protein, demonstrating that the canine disease is a true homologue of human X-linked SCID. 37 refs., 3 figs.

  14. Repression of miR-17-5p with elevated expression of E2F-1 and c-MYC in non-metastatic hepatocellular carcinoma and enhancement of cell growth upon reversing this expression pattern

    SciTech Connect (OSTI)

    El Tayebi, H.M.; Omar, K.; Hegy, S.; El Maghrabi, M.; El Brolosy, M. [The Molecular Pathology Research Group, Department of Pharmacology and Toxicology, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo (Egypt)] [The Molecular Pathology Research Group, Department of Pharmacology and Toxicology, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo (Egypt); Hosny, K.A. [Department of General Surgery, Faculty of Medicine, Cairo University, Cairo (Egypt)] [Department of General Surgery, Faculty of Medicine, Cairo University, Cairo (Egypt); Esmat, G. [Department of Endemic Medicine and Hepatology, Cairo University, Cairo (Egypt)] [Department of Endemic Medicine and Hepatology, Cairo University, Cairo (Egypt); Abdelaziz, A.I., E-mail: ahmed.abdel-aziz@guc.edu.eg [The Molecular Pathology Research Group, Department of Pharmacology and Toxicology, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo (Egypt)

    2013-05-10

    Highlights: •The oncogenic miR-17-5p is downregulated in non-metastatic hepatocellular carcinoma patients. •E2F-1 and c-MYC transcripts are upregulated in non-metastatic HCC patients. •miR-17-5p forced overexpression inhibited E2F-1 and c-MYC expression in HuH-7 cells. •miR-17-5p mimicking increased HuH-7 cell growth, proliferation, migration and colony formation. •miR-17-5p is responsible for HCC progression among the c-MYC/E2F-1/miR-17-5p triad members. -- Abstract: E2F-1, c-MYC, and miR-17-5p is a triad of two regulatory loops: a negative and a positive loop, where c-MYC induces the expression of E2F-1 that induces the expression of miR-17-5p which in turn reverses the expression of E2F-1 to close the loop. In this study, we investigated this triad for the first time in hepatocellular carcinoma (HCC), where miR-17-5p showed a significant down-regulation in 23 non-metastatic HCC biopsies compared to 10 healthy tissues; however, E2F-1 and c-MYC transcripts were markedly elevated. Forced over-expression of miR-17-5p in HuH-7 cells resulted in enhanced cell proliferation, growth, migration and clonogenicity with concomitant inhibition of E2F-1 and c-MYC transcripts expressions, while antagomirs of miR-17-5p reversed these events. In conclusion, this study revealed a unique pattern of expression for miR-17-5p in non-metastatic HCC patients in contrast to metastatic HCC patients. In addition we show that miR-17-5p is the key player among the triad that tumor growth and spread.

  15. In: Proceedings of the 88th Annual Meeting (held June 18-23 in San Antonio, TX), Air and Waste Management Association, Pittsburgh, Pennsylvania, June 1995, Paper No. 95-TA42.02, 1995 H.C. Frey and A.C. Cullen

    E-Print Network [OSTI]

    Frey, H. Christopher

    Meeting Air & Waste Management Association Pittsburgh, PA Presented at: 88th Annual Meeting of the Air & Waste Management Association San Antonio, Texas June 18-23, 1995 #12;2 INTRODUCTION Virtually allIn: Proceedings of the 88th Annual Meeting (held June 18-23 in San Antonio, TX), Air and Waste

  16. Localized Immunotherapy via Liposome-Anchored Anti-CD137 + IL-2 Prevents Lethal Toxicity and Elicits Local and Systemic Antitumor Immunity

    E-Print Network [OSTI]

    Kwong, Brandon

    Immunostimulatory agonists such as anti-CD137 and interleukin (IL)-2 have elicited potent antitumor immune responses in preclinical studies, but their clinical use is limited by inflammatory toxicities that result upon ...

  17. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando AR N. 12/2014 del 11/12/2014 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 24 novembre 2014 Fisiologia e Farmacologia "Vittorio Erspamer"; DISPONE Art.1 ­ Sono approvati gli Fisiologia e Farmacologia "Vittorio Erspamer" di questa Università per il settore

  18. A study of muon neutrino disappearance with the MINOS detectors and the NuMI neutrino beam

    SciTech Connect (OSTI)

    Marshall, John Stuart; /Cambridge U.

    2008-06-01

    This thesis presents the results of an analysis of {nu}{sub {mu}} disappearance with the MINOS experiment, which studies the neutrino beam produced by the NuMI facility at Fermi National Accelerator Laboratory. The rates and energy spectra of charged current {nu}{sub {mu}} interactions are measured in two similar detectors, located at distances of 1 km and 735 km along the NuMI beamline. The Near Detector provides accurate measurements of the initial beam composition and energy, while the Far Detector is sensitive to the effects of neutrino oscillations. The analysis uses data collected between May 2005 and March 2007, corresponding to an exposure of 2.5 x 10{sup 20} protons on target. As part of the analysis, sophisticated software was developed to identify muon tracks in the detectors and to reconstruct muon kinematics. Events with reconstructed tracks were then analyzed using a multivariate technique to efficiently isolate a pure sample of charged current {nu}{sub {mu}} events. An extrapolation method was also developed, which produces accurate predictions of the Far Detector neutrino energy spectrum, based on data collected at the Near Detector. Finally, several techniques to improve the sensitivity of an oscillation measurement were implemented, and a full study of the systematic uncertainties was performed. Extrapolating from observations at the Near Detector, 733 {+-} 29 Far Detector events were expected in the absence of oscillations, but only 563 events were observed. This deficit in event rate corresponds to a significance of 4.3 standard deviations. The deficit is energy dependent and clear distortion of the Far Detector energy spectrum is observed. A maximum likelihood analysis, which fully accounts for systematic uncertainties, is used to determine the allowed regions for the oscillation parameters and identifies the best fit values as {Delta}m{sub 32}{sup 2} = 2.29{sub -0.14}{sup +0.14} x 10{sup -3} eV{sup 2} and sin{sup 2} 2{theta}{sub 23} > 0.953 (68% confidence level). The models of neutrino decoherence and decay are disfavored at the 5.0{sigma} and 3.2{sigma} levels respectively, while the no oscillation model is excluded at the 9.4{sigma} level.

  19. Activation of IL-2 receptor {alpha}-chain gene by individual members of the rel oncogene family in association with serum response factor

    SciTech Connect (OSTI)

    Pierce, J.W.; Jamieson, C.A.; Ross, J.L.

    1995-08-15

    Expression of the IL-2R{alpha} gene is regulated by members of the c-Rel/NF-{kappa}B family of transcription factors binding to the {kappa}B site in the promoter. Previous work has not defined the role of individual members of the c-Rel family in the activation of the IL-2R{alpha} gene. Using the COS cell system, we were able to reconstitute the regulation of the IL-2R{alpha} promoter by expressing cloned Rel family members with serum response factor (SRF). We found that c-rel alone activated the IL-2R{alpha} promoter only weakly but worked with the p50 subunit of NF-{kappa}B (NFKB1) to give a higher level of expression. We showed that c-rel heterodimerizes with p50 and the amount of this heterodimer correlated with the level of IL-2R{alpha} gene expression. Our results provide evidence that c-rel/p50 heterodimers activate gene expression in the context of a cellular promoter. We show that c-rel or p65 can cooperate with SRF in the activation of this promoter and the transactivation by c-rel with SRF was enhanced by p50. Synergistic activation required both {kappa}B an CArG sites, and binding studies show that these that these adjacent sites can be occupied simultaneously. The transactivation observed with cloned transcription factors mimics the physiologic induction of the IL-2R{alpha} gene since multiple sequence elements cooperate to give gene activation. The data support the model that c-rel/p50 or p65 can cooperate with SRF to specifically target the expression of the IL-2R{alpha} gene in activated T cells.

  20. Approach to Recover Hydrocarbons from Currently Off-Limit Areas of the Antrim Formation, MI Using Low-Impact Technologies

    SciTech Connect (OSTI)

    James Wood; William Quinlan

    2008-09-30

    The goal of this project was to develop and execute a novel drilling and completion program in the Antrim Shale near the western shoreline of Northern Michigan. The target was the gas in the Lower Antrim Formation (Upper Devonian). Another goal was to see if drilling permits could be obtained from the Michigan DNR that would allow exploitation of reserves currently off-limits to exploration. This project met both of these goals: the DNR (Michigan Department of Natural Resources) issued permits that allow drilling the shallow subsurface for exploration and production. This project obtained drilling permits for the original demonstration well AG-A-MING 4-12 HD (API: 21-009-58153-0000) and AG-A-MING 4-12 HD1 (API: 21-009-58153-0100) as well as for similar Antrim wells in Benzie County, MI, the Colfax 3-28 HD and nearby Colfax 2-28 HD which were substituted for the AG-A-MING well. This project also developed successful techniques and strategies for producing the shallow gas. In addition to the project demonstration well over 20 wells have been drilled to date into the shallow Antrim as a result of this project's findings. Further, fracture stimulation has proven to be a vital step in improving the deliverability of wells to deem them commercial. Our initial plan was very simple; the 'J-well' design. We proposed to drill a vertical or slant well 30.48 meters (100 feet) below the glacial drift, set required casing, then angle back up to tap the resource lying between the base to the drift and the conventional vertical well. The 'J'-well design was tested at Mancelona Township in Antrim County in February of 2007 with the St. Mancelona 2-12 HD 3.

  1. Algebra (Informatica) 24 marzo 2004 Con pi`u di 18 punti si pu`o fare l'orale o accettare il voto dello scritto (30 e lode per chi

    E-Print Network [OSTI]

    Catenacci, Roberto

    Algebra (Informatica) ­ 24 marzo 2004 Con pi`u di 18 punti si pu`o fare l'orale o accettare il voto

  2. Algebra (Informatica) 22 giugno 2004 Con 18 o pi`u punti si pu`o fare l'orale o accettare il voto dello scritto (30 e lode per chi risolve

    E-Print Network [OSTI]

    Catenacci, Roberto

    Algebra (Informatica) ­ 22 giugno 2004 Con 18 o pi`u punti si pu`o fare l'orale o accettare il voto

  3. Immunosuppressive effect of the anti-IL-2-receptor monoclonal antibody, AMT-13, on organ-cultured fetal pancreas allograft survival

    SciTech Connect (OSTI)

    Burkhardt, K.; Loughnan, M.S.; Diamantstein, T.; Mandel, T.E.

    1988-11-01

    Recently, prolongation of cardiac allograft survival in mice was reported using a rat anti-IL-2R mAb (AMT-13). However, its immunosuppressive action in vivo, alone and in combination with other immunosuppressants, and its effect on other organ transplants has not been extensively studied. We grafted cultured fetal pancreas from CBA (H-2k) donors to Balb/c (H-2d) mice. Recipients were treated with 10 consecutive daily injections each of 20 micrograms AMT-13 only, or with an additional mild immunosuppression of 350 rads irradiation. Control groups received rat immunoglobulin or 350 rads irradiation. Graft survival and the phenotype of infiltrating cells were assessed histologically and immunocytochemically on days 12, 17, and 21, and soluble IL-2R levels were measured in the serum with a quantitative ELISA in all recipients. Two of five grafts in the AMT-13-treated group had islets on day 12 posttransplantation despite lymphocytic infiltration in all grafts, while at this time all grafts of rat Ig treated control mice were completely rejected with only scar tissue and a few lymphocytes remaining. Additional immunosuppression with 350 rads irradiation had a marked additive effect with AMT-13. Soluble IL-2R levels in the serum of untreated recipients were not elevated compared with normal serum levels, but recipients injected with AMT-13 had multifold increased soluble IL-2R levels. The percentage of IL-2R+ cells in the grafts of AMT-13-treated animals was either normal (less than 5%) or increased (20%) in the additionally irradiated mice, providing strong evidence that the immunosuppressive effect of AMT-13 is not due to a depletion of activated IL-2R+ lymphocytes.

  4. Thermal spray removal of lead-based paint from the viaduct bridge at Rock Island Arsenal, IL. Final report

    SciTech Connect (OSTI)

    Boy, J.H.; Weber, R.A.; Kumar, A.

    1998-06-01

    This report documents a field demonstration at the Rock Island Arsenal, IL, that validated the thermal spray vitrification (TSV) process as a safe and effective technique for removing lead-based paint from a steel bridge. Specially formulated glass was applied in a molten state to painted steel using a conventional thermal spray application system. The molten glass reacts with the paint, and encapsulates the lead. The cooled glass readily cracks and falls off, removing the paint. After onsite remelting of the glass waste to complete the encapsulation process, the final waste product is chemically inert and may be disposed of in a regular landfill. The Illinois Environmental Protection Agency, Division of Air Pollution Control determined that the glass remelt process could be considered a paint-removal operation for which no air quality permit was required.

  5. Ecloud Build-Up Simulations for the FNAL MI for a Mixed Fill Pattern: Dependence on Peak SEY and Pulse Intensity During the Ramp

    SciTech Connect (OSTI)

    Furman, M. A.

    2010-12-11

    We present simulation results of the build-up of the electron-cloud density n{sub e} in three regions of the FNAL Main Injector (MI) for a beam fill pattern made up of 5 double booster batches followed by a 6th single batch. We vary the pulse intensity in the range N{sub t} = (2-5) x 10{sup 13}, and the beam kinetic energy in the range E{sub k} = 8-120 GeV. We assume a secondary electron emission model qualitatively corresponding to TiN, except that we let the peak value of the secondary electron yield (SEY) {delta}{sub max} vary as a free parameter in a fairly broad range. Our main conclusions are: (1) At fixed N{sub t} there is a clear threshold behavior of n{sub e} as a function of {delta}{sub max} in the range {approx} 1.1-1.3. (2) At fixed {delta}{sub max}, there is a threshold behavior of n{sub e} as a function of N{sub t} provided {delta}{sub max} is sufficiently high; the threshold value of N{sub t} is a function of the characteristics of the region being simulated. (3) The dependence on E{sub k} is weak except possibly at transition energy. Most of these results were informally presented to the relevant MI personnel in April 2010.

  6. Dans l'espace Le problme en volume est moins simple qu'il n'en a l'air.

    E-Print Network [OSTI]

    Pansu, Pierre

    Dans l'espace Le problème en volume est moins simple qu'il n'en a l'air. Cela ressemble à une de savon maximise l'aire enserrée par la ficelle (en minimisant l'aire du complémentaire). A New

  7. International Weed Science Congress, Vancouver, Canada. 2025 June, 2008. p 53. [Invited] Lisa J. Rew, Hal Balbach, US Army ERDC, Champaign, IL.

    E-Print Network [OSTI]

    Maxwell, Bruce D.

    J. Rew, Hal Balbach, US Army ERDC, Champaign, IL. Evaluating the role of vehicles by vehicles, and thereafter, by natural population expansion in the moredisturbed environments along the right of way. Plant propagules (seeds and other reproductive parts) have been observed on vehicles

  8. In Proceedings of Fourth IEEE International Workshop on Source Code Analysis and Manipulation, Chicago, IL, September 2004, pp. 17-26. Copyright 2004 IEEE Computer Society Press.

    E-Print Network [OSTI]

    Lakhotia, Arun

    , Chicago, IL, September 2004, pp. 17-26. Copyright © 2004 IEEE Computer Society Press. Abstract Stack Graph to Detect Obfuscated Calls in Binaries Arun Lakhotia and Eric Uday Kumar Center for Advanced Computer by anti-virus scanners [6, 14, 17]. The primary goal of obfuscation is to increase the effort involved

  9. IL NUOVO CIMENTO Vol. 110 B, N. 2 Febbraio 1995 A novel method to detect quantum states of the radiation field

    E-Print Network [OSTI]

    Paris, Matteo G. A.

    . --- We propose a new method for detecting the density matrix of the radiation field via optical homodyneIL NUOVO CIMENTO Vol. 110 B, N. 2 Febbraio 1995 A novel method to detect quantum states of the radiation field G. M. D'Ariano ( 1 )( 2 ), Chiara Macchiavello( 1 ), Matteo G. A. Paris( 1 ) ( 1

  10. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando n. 08/2011-Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    .04.2011 e del 19.04.2011; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia del Consiglio di Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 20 ottobre 2011 di Fisiologia e Farmacologia DISPONE Art.1 ­ Sono approvati gli atti della selezione pubblica per il

  11. IL DIRETTORE Visti i DD.MM. 4.10.2000 e 9.1.2001 concernenti la rideterminazione, l'aggiornamento

    E-Print Network [OSTI]

    Di Pillo, Gianni

    Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" e la Fondazione "Enrico ed Enrica Sovena", con chemiopreventivi"; Vista la Delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer Fisiologia e Farmacologia "Vittorio Erspamer" ad attivare la procedura per il reclutamento di un ricercatore

  12. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando n. 02/2012 del 26 giugno 2012 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    .04.2011; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 20 Fisiologia e Farmacologia "Vittorio Erspamer" del 27 luglio 2012 nella quale è stata approvata la nomina giudicatrice e conservati presso il Dipartimento di Fisiologia e Farmacologia DISPONE Art.1 ­ Sono approvati

  13. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando n. 10/2012 del 6 dicembre 2012 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    .04.2011; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 19 Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 16 gennaio 2013 nella quale è stata approvata Commissione giudicatrice e conservati presso il Dipartimento di Fisiologia e Farmacologia DISPONE Art.1 ­ Sono

  14. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando n. 08/2013 dell'8/11/2013 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    Consiglio del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 29 ottobre 2013 nella quale Dipartimento di Fisiologia e Farmacologia DISPONE Art.1 ­ Sono approvati gli atti della selezione pubblica per Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" di questa Università per il settore scientifico

  15. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando n. 06/2012 dell'8 agosto 2012 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    .04.2011; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 27 l'8 agosto 2012; VISTA la delibera del Consiglio di Dipartimento di Fisiologia e Farmacologia conservati presso il Dipartimento di Fisiologia e Farmacologia DISPONE Art.1 ­ Sono approvati gli atti della

  16. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando n. 06/2011 del 29 luglio 2011 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    , rispettivamente del 12.04.2011 e del 19.04.2011; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 23 settembre 2011 nella quale è stata Commissione giudicatrice e conservati presso il Dipartimento di Fisiologia e Farmacologia DISPONE Art.1 ­ Sono

  17. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando n. 07/2012 del 17 ottobre 2012 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    .04.2011; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 16 Fisiologia e Farmacologia "Vittorio Erspamer" del 20 novembre 2012 nella quale è stata approvata la nomina Commissione giudicatrice e conservati presso il Dipartimento di Fisiologia e Farmacologia DISPONE Art.1 ­ Sono

  18. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando n. 1/2012-Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 30 gennaio pubblicato il 2 febbraio 2012; VISTA la delibera del Consiglio di Dipartimento di Fisiologia e Farmacologia Dipartimento di Fisiologia e Farmacologia DISPONE Art.1 ­ Sono approvati gli atti della selezione pubblica per

  19. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando n. 11/2011-Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 30 maggio 2011 Fisiologia e Farmacologia "Vittorio Erspamer" del 13 dicembre 2011 nella quale è stata approvata la nomina Commissione giudicatrice e conservati presso il Dipartimento di Fisiologia e Farmacologia DISPONE Art.1 ­ Sono

  20. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando n. 03/2012 del 26 giugno 2012 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    .04.2011; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 20 Consiglio di Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 27 luglio 2012 nella quale è 5 ottobre 2012 dalla Commissione giudicatrice e conservati presso il Dipartimento di Fisiologia e

  1. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando n. 04/2013 del 12 marzo 2013 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    .04.2011; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 13 Consiglio di Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 10 aprile 2013 nella quale è 2013 dalla Commissione giudicatrice e conservati presso il Dipartimento di Fisiologia e Farmacologia

  2. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando n. 04/2011 del 1 giugno 2011 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    , rispettivamente del 12.04.2011 e del 19.04.2011; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e Fisiologia e Farmacologia "Vittorio Erspamer" del 7 luglio 2011 nella quale è stata approvata la nomina della giudicatrice e conservati presso il Dipartimento di Fisiologia e Farmacologia DISPONE Art.1 ­ Sono approvati

  3. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando n. 06/2013 del 18 settembre 2013 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    .04.2011; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 26 Dipartimento di Fisiologia e Farmacologia DISPONE Art.1 ­ Sono approvati gli atti della selezione pubblica per Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" di questa Università per il settore scientifico

  4. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando n. 05/2012 del 1 agosto 2012 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    .04.2011; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 27 Fisiologia e Farmacologia "Vittorio Erspamer" del 18 settembre 2012 nella quale è stata approvata la nomina giudicatrice e conservati presso il Dipartimento di Fisiologia e Farmacologia DISPONE Art.1 ­ Sono approvati

  5. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando n. 13/2011-Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 10 novembre bando pubblicato l'11 novembre 2011; VISTA la delibera del Consiglio di Dipartimento di Fisiologia e e conservati presso il Dipartimento di Fisiologia e Farmacologia DISPONE Art.1 ­ Sono approvati gli

  6. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando n. 09/2013 dell'8/11/2013 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    , rispettivamente del 12.04.2011 e del 19.04.2011; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e Dipartimento di Fisiologia e Farmacologia DISPONE Art.1 ­ Sono approvati gli atti della selezione pubblica per Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" di questa Università per il settore scientifico

  7. Selezione pubblica per il conferimento di n. 6 assegni per collaborazione ad attivit di ricerca Bando AR N. 13/2014 del 16/12/2014 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    di Fisiologia e Farmacologia "Vittorio Erspamer" sono stati attribuiti n. 6 assegni di ricerca.303,42; CONSIDERATO che il Dipartimento di Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer", appartenente a disposizione nel Dipartimento; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia

  8. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando n. 14/2011-Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 13 dicembre; VISTA la delibera del Consiglio di Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 30 Fisiologia e Farmacologia DISPONE Art.1 ­ Sono approvati gli atti della selezione pubblica per il

  9. Selezione pubblica per il conferimento di n. 1 assegno per collaborazione ad attivit di ricerca Bando n. 11/2012 del 6 dicembre 2012 -Approvazione atti

    E-Print Network [OSTI]

    Di Pillo, Gianni

    .04.2011; VISTA la delibera del Consiglio del Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 19 Dipartimento di Fisiologia e Farmacologia "Vittorio Erspamer" del 16 gennaio 2013 nella quale è stata approvata Commissione giudicatrice e conservati presso il Dipartimento di Fisiologia e Farmacologia DISPONE Art.1 ­ Sono

  10. ISRAEL JOURNAL OF ECOLOGY & EVOLUTION, Vol. 52, 2006, pp. 263279 *Author to whom correspondence should be addressed. E-mail: dbarash@cs.bgu.ac.il

    E-Print Network [OSTI]

    Barash, Danny

    should be addressed. E-mail: dbarash@cs.bgu.ac.il Accepted February 2007. AdAptive MutAtions in Rn rearrangement. We would like to check whether such mutations could be adaptive mutations that may have on both slopes. We expect that further results will shed light on the mutational differences of TPP

  11. Institute for Food Safety and Health | 1602 South Archer Road | Summit-Argo, IL 60501 ifsh@iit.edu | www.iit.edu/ifsh

    E-Print Network [OSTI]

    Heller, Barbara

    Institute for Food Safety and Health | 1602 South Archer Road | Summit-Argo, IL 60501 ifsh,000 * Companies with a revenue of >$1 billion, but whose food business sector is less than $1 billion (proven, but not lower. Please indicate the area(s) of particular interest to your company: ______________ Food

  12. ROS and NF-{kappa}B are involved in upregulation of IL-8 in A549 cells exposed to multi-walled carbon nanotubes

    SciTech Connect (OSTI)

    Ye Shefang Wu Yihui; Hou Zhenqing; Zhang Qiqing

    2009-02-06

    Carbon nanotubes (CNTs) have potential applications in biosensors, tissue engineering, and biomedical devices because of their unique physico-chemical, electronic and mechanical properties. However, there is limited literature data available concerning the biological properties and toxicity of CNTs. This study aimed to assess the toxicity exhibited by multi-walled CNTs (MWCNTs) and to elucidate possible molecular mechanisms underlying the biological effects of MWCNTs in A549 cells. Exposing A549 cells to MWCNTs led to cell death, changes in cell size and complexity, reactive oxygen species (ROS) production, interleukin-8 (IL-8) gene expression and nuclear factor (NF)-{kappa}B activation. Treatment of A549 cells with antioxidants prior to adding MWCNTs decreased ROS production and abrogated expression of IL-8 mRNA. Pretreatment of A549 cells with NF-{kappa}B inhibitors suppressed MWCNTs-induced IL-8 mRNA expression. These results indicate that MWCNTs are able to induce expression of IL-8 in A549 cells, at least in part, mediated by oxidative stress and NF-{kappa}B activation.

  13. Volume 103. number 4 CHEhIlCAL PHYSICS LETTERS 6 January 1984 INFLUENCE OF ELECTRON AND NUCLEAR SPIN ON PHOTOFRAGMENT ALIGNMENT

    E-Print Network [OSTI]

    Volume 103. number 4 CHEhIlCAL PHYSICS LETTERS 6 January 1984 INFLUENCE OF ELECTRON AND NUCLEAR generally fragment when they are excited with photons of energy higher than their dissociation Limit Companies Foundation, Inc. to be adlusted for the effects of spin angular momen- ta that are not aligned

  14. Introduction au HTML Comment le HTML est-il n ? En fait, tout commence quand TIM BERNERS-LEE cre une

    E-Print Network [OSTI]

    Vellend, Mark

    ). Le langage HTML ne se rencontre pas exclusivement sur le web, celui ci est également utilisé pourIntroduction au HTML Naissance Comment le HTML est-il né ? En fait, tout commence quand TIM BERNERS'époque "la mère de tous les réseaux" : Internet. Le World Wide Web (W.W.W.) est constitué de pages Web. Ces

  15. Full-System Analysis and Characterization of Interactive Smartphone Applications

    E-Print Network [OSTI]

    Wenisch, Thomas F.

    University of Michigan - Ann Arbor, MI {atgutier, rdreslin, twenisch, tnm}@umich.edu Ali Saidi, Chris Emmons, Nigel Paver ARM - Austin, TX {ali.saidi, chris.emmons, nigel.paver}@arm.com Abstract--Smartphones have

  16. TITLE AUTHORS SUBJECT SUBJECT RELATED DESCRIPTION PUBLISHER AVAILABILI...

    Office of Scientific and Technical Information (OSTI)

    J He Z University of Michigan Ann Arbor MI United States Mackin D Beddar S MD Anderson Cancer Center Houston TX United States Zheng Y Procure Proton Therapy Center Oklahoma City OK...

  17. The Graduate Certification in Community Engagement at

    E-Print Network [OSTI]

    and evaluation 3. Co-building effective partnerships 4. Capacity-building for mutual benefit 5. Logic models Center, TX ­ Burcham Hills Integrative Dance project in East Lansing, MI ­ Smart Commute project

  18. Multiple protein kinase pathways mediate amplified IL-6 release by human lung fibroblasts co-exposed to nickel and TLR-2 agonist, MALP-2

    SciTech Connect (OSTI)

    Gao Fei; Brant, Kelly A.; Ward, Rachel M.; Cattley, Richard T.; Barchowsky, Aaron [Department of Environmental and Occupational Health, Center for Free Radical and Antioxidant Health, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15219 (United States); Fabisiak, James P., E-mail: fabs@pitt.ed [Department of Environmental and Occupational Health, Center for Free Radical and Antioxidant Health, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15219 (United States)

    2010-09-01

    Microbial stimuli and atmospheric particulate matter (PM) interact to amplify the release of inflammatory and immune-modulating cytokines. The basis of this interaction, however, is not known. Cultured human lung fibroblasts (HLF) were used to determine whether various protein kinase pathways were involved in the release of IL-6 following combined exposure to the PM-derived metal, Ni, and M. fermentans-derived macrophage-activating lipopeptide 2 (MALP-2), a toll-like receptor 2 agonist. Synergistic release of IL-6 by MALP-2 and NiSO{sub 4} was obvious after 8 h of co-stimulation and correlated with a late phase accumulation of IL-6 mRNA. Ni and MALP-2, alone or together, all led to rapid and transient phosphorylations of ERK{sub 1/2} and JNK/SAPK of similar magnitude. p38 phosphorylation, however, was observed only after prolonged treatment of cells with both stimuli together. A constitutive level of PI3K-dependent Akt phosphorylation remained unchanged by Ni and/or MALP-2 exposure. IL-6 induced by Ni/MALP-2 co-exposure was partially dependent on activity of HIF-1{alpha} and COX-2 as shown by targeted knockdown using siRNA. IL-6 release in response to Ni/MALP-2 was partially sensitive to pharmacological inhibition of ERK{sub 1/2}, p38, and PI3K signaling. The protein kinase inhibitors had minimal or no effects on Ni/MALP-2-induced accumulation of HIF-1{alpha} protein, however, COX-2 expression and, more markedly PGE{sub 2} production, were suppressed by LY294002, SB203580, and U0126. Thus, Ni/MALP-2 interactions involve multiple protein kinase pathways (ERK{sub 1/2}, p38, and PI3K) that modulate events downstream from the early accumulation of HIF-1{alpha} to promote IL-6 gene expression directly or secondarily, through COX-2-derived autocrine products like PGE{sub 2}.

  19. \\\\mi\\home\\gillow\\LaTeX\\Comp\\Safety\\Risk-Assessments\\Roof\\Sedum Roof Area Roof Access Risk Assessments 3th March 2014.docx `Sedum' Roof Area(s)/Roof Access Risk Assessments

    E-Print Network [OSTI]

    \\\\mi\\home\\gillow\\LaTeX\\Comp\\Safety\\Risk-Assessments\\Roof\\Sedum Roof Area Roof Access Risk Assessments 3th March 2014.docx `Sedum' Roof Area(s)/Roof Access Risk Assessments DEPARTMENT: Andrew Wiles March 2015 Brief description of area and location Roof tops, walkways, and Fire Route. Sedum' Roof Area

  20. 1.Physics Department, Colorado School of Mines, Golden, CO 2. National Renewable Energy Laboratory, Golden, CO 3. United Solar Ovonic, LLC Troy, MI, United States THERMAL ACTIVATION OF DEEP OXYGEN DEFECT FORMATION AND HYDROGEN EFFUSION

    E-Print Network [OSTI]

    1.Physics Department, Colorado School of Mines, Golden, CO 2. National Renewable Energy Laboratory, Golden, CO 3. United Solar Ovonic, LLC Troy, MI, United States BACKGROUND THERMAL ACTIVATION OF DEEP was partially supported by a DOE grant through United Solar Ovonics, Inc., under the Solar America Initiative

  1. Page 274 Courses: Chemistry (CHEM) Sonoma State University 2015-2016 Catalog CHeM 125A QuAntitAtive generAL CHeMiStry (5)

    E-Print Network [OSTI]

    Ravikumar, B.

    Page 274 Courses: Chemistry (CHEM) Sonoma State University 2015-2016 Catalog CHeM 125A QuAntitAtive generAL CHeMiStry (5) Lecture, 3 hours; discussion 1 hour; laboratory 3 hours (5 units). This one-year analytical general chemistry course is designed for freshmen Chemistry majors, Biochemistry majors, or others

  2. Visto il Reg continuativa

    E-Print Network [OSTI]

    Guidoni, Leonardo

    cond d attività di ric cerca in psico NTO DI UN IN DELL'UNIVE OLOGIA AM razione coord onale in vigo vo

  3. AIR M A IL

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouth DakotaRobbins and Myers Co -VANaval Ordnance,:n5.5.8GE 1A L L'-

  4. IL Wted States Government

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouth DakotaRobbins and700, 1.Reports1E~ S·D3GraniteS T A/ I'

  5. Il.-'",.'

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouth DakotaRobbins and700, 1.Reports1E~ S·D3GraniteS T A/

  6. '~IIf[l.frf511l1!1:1f~!UJK~Jlff8.!rJi ,if[iijt!JfJ'Q,~li~JiIJtllrl~~Il.k!!

    E-Print Network [OSTI]

    Sereno, Martin

    "8i~1iJilI I!Jil(tll"IIJjill!.~I!l~181L8JIliIt~!JI.r~ff}11 l§ilStfJ~fiflfiJ~i.~:..1:I~..~t!il. I~flriffiiti!!ifJf~I[.Jltr[itil~!jifr~tii!lfJ!irl I55lIII!i~f[tif;JB1~191~!a if[iff.~fijll!i~I~!B-ii!I1 1i

  7. University of Texas, Austin Austin, TX 78712

    E-Print Network [OSTI]

    Gutowski, Timothy

    with the Department of Energy, to fund a study through the World Technology Evaluation Consortium WTEC that would waste, 3 energy, and 4 carbon emissions. Manufacturing is also a heavy user of water, and there have any other country in the world. This is true both on an absolute scale as well as a per capita scale 2

  8. Vulnerability Assessment for Hood County, TX 

    E-Print Network [OSTI]

    Aldalbahi, Farisal; Cousins, Tiffany; Franks, Kristie; Hamidah, Nur; Herring, Kalen; Kirimli, Ridvan; Rojas, Ricardo Maga; McCharen, Robert; Paiz-Tabash, William; Phillips, Ellen; Thapa, Jeewasmi; Wallick, Andrew; Yan, Wenqian; Zhang, Yixun

    2015-01-01

    Looking forward, we mapped the 100-year and 500-year floodplains in the County. A 100-year floodplain indicates areas that have a 1% chance each year of flooding. The majority of the floodplain follows the Brazos River, as would be expected, and its...

  9. Alamo, TX Natural Gas Exports to Mexico

    Gasoline and Diesel Fuel Update (EIA)

    Annual Download Series History Download Series History Definitions, Sources & Notes Definitions, Sources & Notes Show Data By: Data Series Area 2009 2010 2011 2012 2013 2014 View...

  10. Helping TxDOT Build Better Bridges

    E-Print Network [OSTI]

    Institute (TTI) researchers work directly with urban and rural communities around Texas to put into practiceYEARS OF RESEARCHER TTI Helps Texas Communities Meet Transportation Challenges #12;2 Publisher://www.facebook.com/ttitamu http://twitter.com/TTI Follow TTI on: 3 TTI Helps Texas Communities Meet Transportation Challenges 4

  11. Micro-Grids for Colonias (TX)

    SciTech Connect (OSTI)

    Dean Schneider; Michael Martin; Renee Berry; Charles Moyer

    2012-07-31

    This report describes the results of the final implementation and testing of a hybrid micro-grid system designed for off-grid applications in underserved Colonias along the Texas/Mexico border. The project is a federally funded follow-on to a project funded by the Texas State Energy Conservation Office in 2007 that developed and demonstrated initial prototype hybrid generation systems consisting of a proprietary energy storage technology, high efficiency charging and inverting systems, photovoltaic cells, a wind turbine, and bio-diesel generators. This combination of technologies provided continuous power to dwellings that are not grid connected, with a significant savings in fuel by allowing power generation at highly efficient operating conditions. The objective of this project was to complete development of the prototype systems and to finalize and engineering design; to install and operate the systems in the intended environment, and to evaluate the technical and economic effectiveness of the systems. The objectives of this project were met. This report documents the final design that was achieved and includes the engineering design documents for the system. The system operated as designed, with the system availability limited by maintenance requirements of the diesel gensets. Overall, the system achieved a 96% availability over the operation of the three deployed systems. Capital costs of the systems were dependent upon both the size of the generation system and the scope of the distribution grid, but, in this instance, the systems averaged $0.72/kWh delivered. This cost would decrease significantly as utilization of the system increased. The system with the highest utilization achieved a capitol cost amortized value of $0.34/kWh produced. The average amortized fuel and maintenance cost was $0.48/kWh which was dependent upon the amount of maintenance required by the diesel generator. Economically, the system is difficult to justify as an alternative to grid power. However, the operational costs are reasonable if grid power is unavailable, e.g. in a remote area or in a disaster recovery situation. In fact, avoided fuel costs for the smaller of the systems in use during this project would have a payback of the capital costs of that system in 2.3 years, far short of the effective system life.

  12. Penitas, TX Natural Gas Exports to Mexico

    Gasoline and Diesel Fuel Update (EIA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustments (Billion Cubic Feet)DecadeYear Jan FebCubic Feet) Annual Download Series History Download Series

  13. Penitas, TX Natural Gas Exports to Mexico

    Gasoline and Diesel Fuel Update (EIA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustments (Billion Cubic Feet)DecadeYear Jan FebCubic Feet) Annual Download Series History Download

  14. Roma, TX Natural Gas Exports to Mexico

    Gasoline and Diesel Fuel Update (EIA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustments (Billion Cubic Feet)DecadeYear Jan3 November 2013 IndependentYear Jan Feb Mar Apr May Jun4Year20,042

  15. Alamo, TX Natural Gas Exports to Mexico

    Gasoline and Diesel Fuel Update (EIA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustments (Billion Cubic Feet)Decade Year-0ProvedDecade2,948 2,724 2,570 2,304 1,670Same0 1 2 2State Offshore

  16. Alamo, TX Natural Gas Exports to Mexico

    Gasoline and Diesel Fuel Update (EIA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustments (Billion Cubic Feet)Decade Year-0ProvedDecade2,948 2,724 2,570 2,304 1,670Same0 1 2 2State

  17. Clint, TX Natural Gas Exports to Mexico

    Gasoline and Diesel Fuel Update (EIA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustments (Billion Cubic Feet)Decade Year-0ProvedDecade2,948CaliforniaFeet) (Million CubicYear Jan..

  18. Hidalgo, TX Natural Gas Exports to Mexico

    Gasoline and Diesel Fuel Update (EIA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustments (Billion Cubic Feet)DecadeYear Jan Feb Mar Apr MayYear JanThousand CubicHealthYear-Month Week 1 Week

  19. Hidalgo, TX Natural Gas Exports to Mexico

    Gasoline and Diesel Fuel Update (EIA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustments (Billion Cubic Feet)DecadeYear Jan Feb Mar Apr MayYear JanThousand CubicHealthYear-Month Week 1 Week0

  20. CleanTX Foundation | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION J APPENDIX E LISTStar EnergyLawler,Coal Technologies Place: FloridaClean EnergyClean

  1. ~txF7D.ptx

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobsMotion toCoal_Budget_Fact_Sheet.pdf More Documents &ER-B-00-03 +

  2. Microsoft Word - abstract-lacognata-tx_2012

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room NewsInformationJessework uses concrete7 Assessment ofLana Cox (803)7-3373MysteryTHE FLUORINE

  3. TX, RRC District 1 Proved Nonproducing Reserves

    U.S. Energy Information Administration (EIA) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home PageMonthly","10/2015"4,"Ames5 Tables July 1996 Energy Information Administration Office of Coal, Nuclear,DecadeYearbyWithdrawalsHome Pageper ThousandTABLE OF39852326 144

  4. TX, RRC District 10 Proved Nonproducing Reserves

    U.S. Energy Information Administration (EIA) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home PageMonthly","10/2015"4,"Ames5 Tables July 1996 Energy Information Administration Office of Coal, Nuclear,DecadeYearbyWithdrawalsHome Pageper ThousandTABLE98 2437,5949 35

  5. TX, RRC District 5 Proved Nonproducing Reserves

    U.S. Energy Information Administration (EIA) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home PageMonthly","10/2015"4,"Ames5 Tables July 1996 Energy Information Administration Office of Coal, Nuclear,DecadeYearbyWithdrawalsHome Pageper909 2,235Changes,800 1 29 12 28

  6. TX, RRC District 6 Proved Nonproducing Reserves

    U.S. Energy Information Administration (EIA) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home PageMonthly","10/2015"4,"Ames5 Tables July 1996 Energy Information Administration Office of Coal, Nuclear,DecadeYearbyWithdrawalsHome Pageper909 2,235Changes,8002 11 16 32

  7. TX, RRC District 8 Proved Nonproducing Reserves

    U.S. Energy Information Administration (EIA) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home PageMonthly","10/2015"4,"Ames5 Tables July 1996 Energy Information Administration Office of Coal, Nuclear,DecadeYearbyWithdrawalsHome6,672 7,206 7,039 7,738

  8. TX, RRC District 9 Proved Nonproducing Reserves

    U.S. Energy Information Administration (EIA) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home PageMonthly","10/2015"4,"Ames5 Tables July 1996 Energy Information Administration Office of Coal, Nuclear,DecadeYearbyWithdrawalsHome6,672 7,206 7,03979010,90411,5225 21 20

  9. TX, State Offshore Proved Nonproducing Reserves

    U.S. Energy Information Administration (EIA) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home PageMonthly","10/2015"4,"Ames5 Tables July 1996 Energy Information Administration Office of Coal, Nuclear,DecadeYearbyWithdrawalsHome6,672 7,2060 0 1 0 0 0 1996-2014 Lease

  10. L'arte in e l'arte di Antonioni: un percorso verso l'astrazione cinematografica

    E-Print Network [OSTI]

    Proietti, Leonardo

    2013-01-01

    come crede, liberamente. Credo importante oggigiorno che ilche mi piace. Quindi, io credo che tutta questa sensibilitàprogetto estetico. Questo credo sia il paradigma artistico

  11. Oceanography | Vol.24, No.128 Ph i l i PPi N e S t r a it S Dy N a mi c S e x Pe r imeNt

    E-Print Network [OSTI]

    Sprintall, Janet

    Oceanography | Vol.24, No.128 Ph i l i PPi N e S t r a it S Dy N a mi c S e x Pe r imeNt Luzon Ocean Zoom of the 2008 sea surface height anomaly from Figure 3c. Oceanography | Vol.24, No.128 ThisarticlehasbeenpublishedinOceanography,Volume24,Number1,aquarterlyjournalofTheOceanographySociety.©2011byTheOceanography

  12. Photoelectron imaging and theoretical study on the structure and chemical binding of the mixed-ligand M(I) complexes, [HMSH]{sup ?} (M = Cu, Ag, and Au)

    SciTech Connect (OSTI)

    Qin, Zhengbo; Liu, Zhiling; Cong, Ran; Xie, Hua; Tang, Zichao, E-mail: zctang@dicp.ac.cn, E-mail: fanhj@dicp.ac.cn; Fan, Hongjun, E-mail: zctang@dicp.ac.cn, E-mail: fanhj@dicp.ac.cn [State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023 (China)] [State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023 (China)

    2014-03-21

    We have reported a combined photoelectron imaging and theoretical study on gaseous mixed-ligand M(I) complexes of [HMSH]{sup ?} (M = Cu, Ag, and Au). With the aid of Franck-Condon simulations, vibrationally resolved photoelectron spectra yield accurate electron affinities of 3.269(6), 3.669(10), and 3.591(6) eV for [HCuSH], [HAgSH], and [HAuSH], respectively. And low-frequency modes are observed: 368(12) cm{sup ?1} for [HCuSH], 286(12) cm{sup ?1} for [HAgSH], and 327(12) cm{sup ?1} for [HAuSH], respectively. Extensive theoretical calculations are performed to aid in the spectral assignments and the calculated values agree well with the experimental observations. Although the S and H atoms have little discrepancy in electronegativity (2.20 for H and 2.54 for S), distinct bonding properties are demonstrated between H–M and M–S bond. It is revealed that there exists significant ionic bonding between M–S in [HMSH]{sup ?} (M = Cu, Ag, and Au), while a gradual transition from ionic behavior between H–Cu in [HCuSH]{sup ?} to quite strong covalent bonding between H–Au in [HAuSH]{sup ?}, supported by a variety of chemical bonding analyses.

  13. The candidate genes TAF5L, TCF7, PDCD1, IL6 and ICAM1 cannot be excluded from having effects in type 1 diabetes

    E-Print Network [OSTI]

    Cooper, Jason D.; Smyth, Deborah J.; Bailey, Rebecca; Payne, Felicity; Downes, Kate; Godfrey, Lisa M.; Masters, Jennifer; Zeitels, Lauren R.; Vella, Adrian; Walker, Neil M.; Todd, John A.

    2007-11-28

    ), suggesting the exist- ence of shared disease loci [13]. In this study, we tested three genes, namely, IL23R, IRF5 and CD40, which have been associated with other immune-mediated diseases (Table 1), including Crohn's disease (CD), psoriasis, SLE and GD... kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner. IBD and psoriasis: ? Duerr et al [69] CD: 547 non-Jewish cases and 548 control cases and 433 controls, OR = 0.45 (0.27–0 10. ? Cargill et al [54] Psoriasis...

  14. Edward S. Rubin Department of Engineering and Public Policy

    E-Print Network [OSTI]

    .5 Saline 2015 FutureGen Alliance Meredosia, IL Oxy 1.0 EOR/Saline 2015 NRG Energy Thompsons, TX Amine ~0 · 235 MWe slipstream at AEP's 1300 MWe Mountaineer Plant · 90% CO2 capture (Alstom Chilled Ammonia

  15. Lancaster-Mineral Point folio, Wisconsin-Iowa-Illinois 

    E-Print Network [OSTI]

    Grant, U. S. (Ulysses Sherman), 1867-1932.

    1907-01-01

    Multiquip) Location CA IA NJ SC WI CAN CO GA ID IL KS TX Total Maquoketa 1 1 Atlanta 1 1 Boise 1 1 Carson 1 1 Cerritos 1 1...

  16. Reconstructing Evolution of Natural Languages: Complexity and Parameterized Algorithms

    E-Print Network [OSTI]

    Xia, Ge "Frank"

    . Wabash Avenue, Chicago, IL 60604-2301. Email: ikanj@cs.depaul.edu. This research was supported in part, Texas A&M University, College Station, TX 77843-3112. Email: gexia@cs.tamu.edu. 1 #12;people began

  17. Labeled Search Trees and Amortized Analysis: Improved Upper Bounds for NP-hard Problems

    E-Print Network [OSTI]

    Xia, Ge "Frank"

    and CCF-0430683. Department of Computer Science, Texas A&M University, College Station, TX 77843. Wabash Avenue, Chicago, IL 60604-2301 Email: ikanj@cs.depaul.edu. Supported in part by DePaul University

  18. Improved Parameterized Upper Bounds for Vertex Cover

    E-Print Network [OSTI]

    Xia, Ge "Frank"

    Department of Computer Science, Texas A&M University, College Station, TX 77843, USA. This author, Chicago, IL 60604-2301, USA. This author was supported in part by DePaul University Competitive Research

  19. Identification of proteins capable of metal reduction from the proteome of the Gram-positive bacterium Desulfotomaculum reducens MI-1 using an NADH-based activity assay

    SciTech Connect (OSTI)

    Otwell, Annie E.; Sherwood, Roberts; Zhang, Sheng; Nelson, Ornella D.; Li, Zhi; Lin, Hening; Callister, Stephen J.; Richardson, Ruth E.

    2015-01-01

    Metal reduction capability has been found in numerous species of environmentally abundant Gram-positive bacteria. However, understanding of microbial metal reduction is based almost solely on studies of Gram-negative organisms. In this study, we focus on Desulfotomaculum reducens MI-1, a Gram-positive metal reducer whose genome lacks genes with similarity to any characterized metal reductase. D. reducens has been shown to reduce not only Fe(III), but also the environmentally important contaminants U(VI) and Cr(VI). By extracting, separating, and analyzing the functional proteome of D. reducens, using a ferrozine-based assay in order to screen for chelated Fe(III)-NTA reduction with NADH as electron donor, we have identified proteins not previously characterized as iron reductases. Their function was confirmed by heterologous expression in E. coli. These are the protein NADH:flavin oxidoreductase (Dred_2421) and a protein complex composed of oxidoreductase FAD/NAD(P)-binding subunit (Dred_1685) and dihydroorotate dehydrogenase 1B (Dred_1686). Dred_2421 was identified in the soluble proteome and is predicted to be a cytoplasmic protein. Dred_1685 and Dred_1686 were identified in both the soluble as well as the insoluble (presumably membrane) protein fraction, suggesting a type of membrane-association, although PSORTb predicts both proteins are cytoplasmic. Furthermore, we show that these proteins have the capability to reduce soluble Cr(VI) and U(VI) with NADH as electron donor. This study is the first functional proteomic analysis of D. reducens, and one of the first analyses of metal and radionuclide reduction in an environmentally relevant Gram-positive bacterium.

  20. Daimler Chrysler Auburn Hills, MI

    E-Print Network [OSTI]

    Papalambros, Panos

    Sponsored by: Automotive Research Center National Automotive Center (NAC) U.S. Army Tank Automotive Research, Development and Engineering Center (TARDEC) U.S. Army Tank-Automotive and Armaments Command (TACOM in ground vehicle simulation. It will present the results of ARC research to university, industry

  1. US ENC MI Site Consumption

    Gasoline and Diesel Fuel Update (EIA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustments (Billion Cubic Feet) Wyoming963 1.969 1.979Coal Consumers inYear JanSales Type: Sales

  2. International Conference on Mathematics, Computational Methods & Reactor Physics (M&C 2009) Saratoga Springs, New York, May 3-7, 2009, on CD-ROM, American Nuclear Society, LaGrange Park, IL (2009)

    E-Print Network [OSTI]

    Danon, Yaron

    2009-01-01

    International Conference on Mathematics, Computational Methods & Reactor Physics (M&C 2009) Saratoga Springs, New York, May 3-7, 2009, on CD-ROM, American Nuclear Society, LaGrange Park, IL (2009.P. Barry Department of Mechanical Aerospace and Nuclear Engineering, Rensselaer Polytechnic Institute 110 8

  3. International Conference on Mathematics, Computational Methods & Reactor Physics (M&C 2009) Saratoga Springs, New York, May 3-7, 2009, on CD-ROM, American Nuclear Society, LaGrange Park, IL (2009)

    E-Print Network [OSTI]

    Danon, Yaron

    2009-01-01

    International Conference on Mathematics, Computational Methods & Reactor Physics (M&C 2009) Saratoga Springs, New York, May 3-7, 2009, on CD-ROM, American Nuclear Society, LaGrange Park, IL (2009 and Nuclear Engineering Troy, New York, 12180 D.P. Barry, G. Leinweber, N.J. Drindak (ret.), J.G. Hoole Knolls

  4. Il materiale contenuto in questo documento utilizzabile unicamente per la preparazione dell'esame di Informatica della Dipartimento di Lingue e Letterature Straniere dell'Universit degli Studi di Torino. Qualsiasi altro utilizzo totale o parziale espres

    E-Print Network [OSTI]

    Anselma, Luca

    'esame di Informatica della Dipartimento di Lingue e Letterature Straniere dell'Università degli Studi di degli Studi di Torino Dipartimento di Lingue e Letterature Straniere Corso di Informatica Studenti J state nascoste 2 Chi è costui? ·Luca Anselma ·Ricercatore di Informatica presso il Dipartimento di

  5. N.B.: Le immagini protette da copyright sono state nascoste Il materiale contenuto in questo documento utilizzabile unicamente per la preparazione dell'esame di Informatica della Facolt di Lingue e

    E-Print Network [OSTI]

    Anselma, Luca

    documento è utilizzabile unicamente per la preparazione dell'esame di Informatica della Facoltà di Lingue e multimedialità Versione: 20/03/2012 Facoltà di Lingue e Letterature Straniere - Corso di Informatica - Laurea - Corso di Informatica - Laurea triennale 3 dell istruzione e dell intrattenimento (es. il CD allegato al

  6. http://physics.technion.ac.il/~ips/webIsrael Physical Society Prof. Cezar Bruma IPS_Join_to_2006_05_06.doc created 2006_04_30 printed: 5/7/2006

    E-Print Network [OSTI]

    Adler, Joan

    ) IPS signed an Agreement with the American Physical Society (APS) www.aps.org All IPS members advantage of our reciprocal arrangements with EPS, APS and IOP · Strengthen our ability to promote physicshttp://physics.technion.ac.il/~ips/webIsrael Physical Society Prof. Cezar Bruma IPS_Join_to_2006

  7. TGF-{beta}1 increases invasiveness of SW1990 cells through Rac1/ROS/NF-{kappa}B/IL-6/MMP-2

    SciTech Connect (OSTI)

    Binker, Marcelo G.; CBRHC Research Center, Buenos Aires ; Binker-Cosen, Andres A.; Gaisano, Herbert Y.; Cosen, Rodica H. de; Cosen-Binker, Laura I.

    2011-02-04

    Research highlights: {yields} Rac1 mediates TGF-{beta}1-induced SW1990 invasion through MMP-2 secretion and activation. {yields} NADPH-generated ROS act downstream of Rac1 in TGF-{beta}1-challenged SW1990 cells. {yields} TGF-{beta}1-stimulated ROS activate NF-{kappa}B in SW1990 cells. {yields} NF{kappa}B-induced IL-6 release is required for secretion and activation of MMP-2 in SW1990 cells. -- Abstract: Human pancreatic cancer invasion and metastasis have been found to correlate with increased levels of active matrix metalloproteinase 2 (MMP-2). The multifunctional cytokine transforming growth factor beta 1 (TGF-{beta}1) has been shown to increase both secretion of MMP-2 and invasion by several pancreatic cancer cell types. In the present study, we investigated the signaling pathway involved in TGF-{beta}1-promoted MMP-2 secretion and invasion by human pancreatic cancer cells SW1990. Using specific inhibitors, we found that stimulation of these tumor cells with TGF-{beta}1 induced secretion and activation of the collagenase MMP-2, which was required for TGF-{beta}1-stimulated invasion. Our results also indicate that signaling events involved in TGF-{beta}1-enhanced SW1990 invasiveness comprehend activation of Rac1 followed by generation of reactive oxygen species through nicotinamide adenine dinucleotide phosphate-oxidase, activation of nuclear factor-kappa beta, release of interleukin-6, and secretion and activation of MMP-2.

  8. A high-throughput three-dimensional cell migration assay for toxicity screening

    E-Print Network [OSTI]

    Diseases, University of Texas Health Science Center, Houston, TX 77030 USA. There is a growing demand,19­21 . These nanoparticles are nontoxic and do not induce an inflammatory cytokine (IL-6, IL-8) response by cells22 they interact and aggregate with each other to form larger 3D cultures. This method has been shown to induce

  9. 323. 1JYNJ;MI(S AND 00!ANTIM3 CF OOGINIC rouJJI'ANl' lNll'RICITrns (}l GAY MINERAlS. Z.Z. 2'bang. Penchu 2'bang and D.L. Sjmks. l:epart:lrent of Plant and Soil Sciences.

    E-Print Network [OSTI]

    Sparks, Donald L.

    323. 1JYNJ;MI(S AND 00!ANTIM3 CF OOGINIC rouJJI'ANl' lNll'RICITrns (}l GAY MINERAlS. Z.Z. 2'bangI.ark. IE 19717-lm The interactions of clay minerals with organic pollutants .ere investigated using

  10. Esame Scritto di Fisica 1 per Biotecnologie -25 Febbraio 2010 Il tempo a disposizione `e di tre ore. E' ammesso l'uso di calcolatrici. Non `e ammesso l'uso di appunti, libri, computer,

    E-Print Network [OSTI]

    Giannozzi, Paolo

    = 4.5 Ã? 105 m/s, diretta lungo l'asse x, in una zona di spazio (x > 0) dove `e presente un campo- generati dalle due cariche. Prendiamo l'asse x lungo l'asse del dipolo, l'origine delle coordinate nel.88 Ã? 1011 NC-1 . Prendiamo il punto P sull'asse delle y, che prendiamo per comodit`a verticale. Nel punto P

  11. Activation of ROS/NF-{kappa}B and Ca{sup 2+}/CaM kinase II are necessary for VCAM-1 induction in IL-1{beta}-treated human tracheal smooth muscle cells

    SciTech Connect (OSTI)

    Luo, S.-F. [Department of Internal Medicine, Chang Gung University, Kwei-San, Tao-Yuan, Taiwan (China); Chang, C.-C.; Lee, I-T. [Department of Physiology and Pharmacology, Chang Gung University, Kwei-San, Tao-Yuan, Taiwan (China); Lee, C.-W. [Department of Nursing, Division of Basic Medical Sciences, Chang Gung Institute of Technology, Chia-Yi, Taiwan (China); Lin, W.-N. [Department of Physiology and Pharmacology, Chang Gung University, Kwei-San, Tao-Yuan, Taiwan (China); Lin, C.-C. [Department of Anesthetics, Chang Gung University, Kwei-San, Tao-Yuan, Taiwan (China); Yang, C.-M. [Department of Physiology and Pharmacology, Chang Gung University, Kwei-San, Tao-Yuan, Taiwan (China)], E-mail: chuenmao@mail.cgu.edu.tw

    2009-05-15

    Histone acetylation regulated by histone acetyltransferases (HATs) and histone deacetylases (HDACs) plays a critical role in the expression of inflammatory genes, such as vascular cell adhesion molecule-1 (VCAM-1). Oxidative processes have been shown to induce VCAM-1 expression. Here, we investigated the mechanisms underlying IL-1{beta}-induced VCAM-1 expression in human tracheal smooth muscle cells (HTSMCs). Our results showed that IL-1{beta} enhanced HTSMCs-monocyte adhesion through up-regulation of VCAM-1, which was inhibited by pretreatment with selective inhibitors of PKC{alpha} (Goe6976), c-Src (PP1), NADPH oxidase [diphenylene iodonium (DPI) and apocynin (APO)], intracellular calcium chelator (BAPTA/AM), PI-PLC (U73122), CaM (calmidazolium chloride), CaM kinase II (KN62), p300 (garcinol), NF-{kappa}B (Bay11-7082), HDAC (trichostatin A), and ROS scavenger [N-acetyl-L-cysteine (NAC)] or transfection with siRNAs of MyD88, PKC{alpha}, Src, p47{sup phox}, p300, and HDAC4. Moreover, IL-1{beta} stimulated NF-{kappa}B and CaMKII phosphorylation through MyD88-dependent PI-PLC/PKC{alpha}/c-Src/ROS and PI-PLC/Ca{sup 2+}/CaM pathways, respectively. Activation of NF-{kappa}B and CaMKII may eventually lead to the acetylation of histone residues and phosphorylation of histone deacetylases. These findings suggested that IL-1{beta} induced VCAM-1 expression via these multiple signaling pathways in HTSMCs. Blockade of these pathways may reduce monocyte adhesion via VCAM-1 suppression and attenuation of the inflammatory responses in airway diseases.

  12. Elementi di Algebra e Logica 2006/'07. Foglio 6 (prima parte). 1. (a) Si consideri il reticolo D12. Stabilire quali tra i seguenti sottoinsiemi di D12 sono sottoreticoli e quali

    E-Print Network [OSTI]

    Pareschi, Giuseppe

    Elementi di Algebra e Logica 2006/'07. Foglio 6 (prima parte). 1. (a) Si consideri il reticolo D12 due operazioni (+ e ·) e di una funzione A A, a a . Quali tra essi soddisfano gli assiomi di Algebra di Boole? (a) A = D12, a + b = mcm(a, b), a · b = mcd(a, b), a = 12/a. (b) A = D30, a + b = mcm(a, b

  13. SUPPLY CHAIN MANAGER CHICAGO, IL

    E-Print Network [OSTI]

    Bustamante, Fabián E.

    or an MBA with emphasis on operations management. Additional training that includes SIX SIGMA, LEAN, CPIM

  14. COME IMMAGINI IL TUO FUTURO?

    E-Print Network [OSTI]

    Schenato, Luca

    -tech,telefonia,automotive,software,robotica,biomedica; ·settoriproduttiviinnovativicomebiomateriali,energierinnovabili,nanotecnologie, domotica,web-business; ·societàdiservizieconsulenza

  15. SUPPLY CHAIN MANAGER CHICAGO, IL

    E-Print Network [OSTI]

    Smilowitz, Karen

    or an MBA with emphasis on operations management. Additional training that includes SIX SIGMA, LEAN, CPIM such as automotive, appliance, and aerospace manufacturers, as well as food, pharmaceuticals, transportation, mining

  16. Il "Sud" come frontiera geosimbolica

    E-Print Network [OSTI]

    Saffioti, Francesca

    2010-01-01

    ad altri contesti. Albert Camus stesso riconosce come non sipensiero meridiano” da Albert Camus, L’uomo in rivolta,Milano: Adelphi, 2004. Camus, Albert. L’uomo in rivolta.

  17. Zinc ferrite nanoparticles activate IL-1b, NFKB1, CCL21 and NOS2 signaling to induce mitochondrial dependent intrinsic apoptotic pathway in WISH cells

    SciTech Connect (OSTI)

    Saquib, Quaiser; Al-Khedhairy, Abdulaziz A.; Ahmad, Javed; Siddiqui, Maqsood A.; Dwivedi, Sourabh; Khan, Shams T.; Musarrat, Javed

    2013-12-01

    The present study has demonstrated the translocation of zinc ferrite nanoparticles (ZnFe{sub 2}O{sub 4}-NPs) into the cytoplasm of human amnion epithelial (WISH) cells, and the ensuing cytotoxicity and genetic damage. The results suggested that in situ NPs induced oxidative stress, alterations in cellular membrane and DNA strand breaks. The [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] (MTT) and neutral red uptake (NRU) cytotoxicity assays indicated 64.48 ± 1.6% and 50.73 ± 2.1% reduction in cell viability with 100 ?g/ml of ZnFe{sub 2}O{sub 4}-NPs exposure. The treated WISH cells exhibited 1.2-fold higher ROS level with 0.9-fold decline in membrane potential (??m) and 7.4-fold higher DNA damage after 48 h of ZnFe{sub 2}O{sub 4}-NPs treatment. Real-time PCR (qPCR) analysis of p53, CASP 3 (caspase-3), and bax genes revealed 5.3, 1.6, and 14.9-fold upregulation, and 0.18-fold down regulation of bcl 2 gene vis-à-vis untreated control. RT{sup 2} Profiler™ PCR array data elucidated differential up-regulation of mRNA transcripts of IL-1b, NFKB1, NOS2 and CCL21 genes in the range of 1.5 to 3.7-folds. The flow cytometry based cell cycle analysis suggested the transfer of 15.2 ± 2.1% (p < 0.01) population of ZnFe{sub 2}O{sub 4}-NPs (100 ?g/ml) treated cells into apoptotic phase through intrinsic pathway. Over all, the data revealed the potential of ZnFe{sub 2}O{sub 4}-NPs to induce cellular and genetic toxicity in cells of placental origin. Thus, the significant ROS production, reduction in ??m, DNA damage, and activation of genes linked to inflammation, oxidative stress, proliferation, DNA damage and repair could serve as the predictive toxicity and stress markers for ecotoxicological assessment of ZnFe{sub 2}O{sub 4}-NPs induced cellular and genetic damage. - Highlights: • First report on the molecular toxicity of ZnFe{sub 2}O{sub 4}-NPs in cells of placental origin • WISH cells treated with ZnFe{sub 2}O{sub 4}-NPs exhibited cytoplasmic localization of NPs. • ZnFe{sub 2}O{sub 4}-NPs induce DNA damage and mitochondrial dysfunction in WISH cells. • ZnFe{sub 2}O{sub 4}-NPs activate inflammatory and oxidative stress signaling in WISH cells. • Elevation of p53, CASP 3, bax and bcl 2 genes affirms intrinsic apoptotic pathway.

  18. Applications Tests of Energy Efficient, Environmentally Friendly Refrigerants 

    E-Print Network [OSTI]

    Nimitz, J.; Glass, S.; McCullough, E.; Dhooge, P.

    1999-01-01

    the Twenty-first National Industrial Energy Technology Conference, Houston, TX, May 12-13, 1999 ~ ::l ;; il fitO(x) ~- f-T (; av~ 30 -----.------r---..,----r-----,-----r----,---r--i 30 E+++ 0 ~ ~ cr:" -10 -20 -20 L... ambient temperatures, and a moderately high global warming potential (GWP). 197 ESL-IE-99-05-29 Proceedings from the Twenty-first National Industrial Energy Technology Conference, Houston, TX, May 12-13, 1999 The Ikon? Refrigerants The original goal...

  19. Search for proton decay via <mi>p>?<mi>?K>+ using 260 <mi>kiloton·year> data of Super-Kamiokande

    SciTech Connect (OSTI)

    Abe, K.; Hayato, Y.; Iyogi, K.; Kameda, J.; Miura, M.; Moriyama, S.; Nakahata, M.; Nakayama, S.; Wendell, R.?A.; Sekiya, H.; Shiozawa, M.; Suzuki, Y.; Takeda, A.; Takenaga, Y.; Ueno, K.; Yokozawa, T.; Kaji, H.; Kajita, T.; Kaneyuki, K.; Lee, K.?P.; Okumura, K.; McLachlan, T.; Labarga, L.; Kearns, E.; Raaf, J.?L.; Stone, J.?L.; Sulak, L.?R.; Goldhaber, M.; Bays, K.; Carminati, G.; Kropp, W.?R.; Mine, S.; Renshaw, A.; Smy, M.?B.; Sobel, H.?W.; Ganezer, K.?S.; Hill, J.; Keig, W.?E.; Jang, J.?S.; Kim, J.?Y.; Lim, I.?T.; Albert, J.?B.; Scholberg, K.; Walter, C.?W.; Wongjirad, T.; Ishizuka, T.; Tasaka, S.; Learned, J.?G.; Matsuno, S.; Smith, S.?N.; Hasegawa, T.; Ishida, T.; Ishii, T.; Kobayashi, T.; Nakadaira, T.; Nakamura, K.; Nishikawa, K.; Oyama, Y.; Sakashita, K.; Sekiguchi, T.; Tsukamoto, T.; Suzuki, A.?T.; Takeuchi, Y.; Ieki, K.; Ikeda, M.; Kubo, H.; Minamino, A.; Murakami, A.; Nakaya, T.; Fukuda, Y.; Choi, K.; Itow, Y.; Mitsuka, G.; Miyake, M.; Mijakowski, P.; Hignight, J.; Imber, J.; Jung, C.?K.; Taylor, I.; Yanagisawa, C.; Ishino, H.; Kibayashi, A.; Koshio, Y.; Mori, T.; Sakuda, M.; Takeuchi, J.; Kuno, Y.; Kim, S.?B.; Okazawa, H.; Choi, Y.; Nishijima, K.; Koshiba, M.; Totsuka, Y.; Yokoyama, M.; Martens, K.; Marti, Ll.; Obayashi, Y.; Vagins, M.?R.; Chen, S.; Sui, H.; Yang, Z.; Zhang, H.; Connolly, K.; Dziomba, M.; Wilkes, R.?J.

    2014-10-14

    We have searched for proton decay via p??K+ using Super-Kamiokande data from April 1996 to February 2013, 260 kiloton•year exposure in total. No evidence for this proton decay mode is found. A lower limit of the proton lifetime is set to ?/B(p??K+)>5.9×1033 years at 90% confidence level.

  20. TxDOT - Certification for Utility Accommodation | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page| Open Energy Information Serbia-EnhancingEt Al.,Turin, New York: Energy ResourcesLake,Fallon | OpenCertification for

  1. TxDOT Access Management Manual | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page| Open Energy Information Serbia-EnhancingEt Al.,Turin, New York: Energy ResourcesLake,Fallon | OpenCertificationAccess

  2. txH2O: Volume 2, Number 3 (Complete) 

    E-Print Network [OSTI]

    Texas Water Resources Institute

    2006-01-01

    of bed profiles in alluvial channels Gokmen Tayfur 1 and Vijay P. Singh 2 Received 7 March 2005; revised 23 February 2006; accepted 10 March 2006; published 21 June 2006. [1] A mathematical model, based on the kinematic wave (KW) theory, is developed... concentration (maximum bed form elevation) strongly affect transient bed profiles. Citation: Tayfur, G., and V. P. Singh (2006), Kinematic wave model of bed profiles in alluvial channels, Water Resour. Res., 42, W06414, doi:10.1029/2005WR004089. 1. Introduction...

  3. Comprehensive Plan & State of the City Lorena,TX 

    E-Print Network [OSTI]

    Pugh, David L.; Ekroth, David; Allen, Brannyn G.; Cummings, Laurie E.; Askew, Christy M.; Allen, Brannyn; Askew, Christy; Davis, Sombra; Dean, Lawrence; He, Xin; Jung, Juchul; Kang, Sang Jun; kwon, Tae Jung; Mabry, Brian; Uhm, Jung; Bubel, Paul; Carroll, Amber; Chan, Hobart; Citzler, Edward; Davis, Matthew; Ellan, Christopher; Erroz, Miguel; Floren, Jathan; Garcia, Eduardo; Garza, Mario; McAffee, Megan; Menefee, James; Molkentine, Aaron; Nesline, Lucian; Polkinghorn, David; Renfrow, Brandon; Steinert, Bo; Treichler, James; Chambers, Byron; Chootimun, Dolratee; Vyas, Paul; Slicker, Joseph

    2001-01-01

    One course developed designs for the construction of a new complex at the existing City Hall site at the intersection of Center and Borden Streets. Another course developed designs for a new complex at the site of the old ...

  4. NCSEC'07 Plano, TX Risk-Based Quantifiable

    E-Print Network [OSTI]

    Tian, Jeff

    of cost, usage, quality, defect, performance, etc. "80:20" rule or Pareto's principle. Units: component

  5. txH2O: Volume 2, Number 1 (Complete) 

    E-Print Network [OSTI]

    Texas Water Resources Institute

    2006-01-01

    Otx volume 1 | number 2 A Publication of the Texas Water Resources Institute Texas Water Resources Institute | Texas Agricultural Experiment Station | Texas Cooperative Extension In This Issue: ? TEXAS? NATURAL LAKE ? PANHANDLE AGRIPARTNERS... Water Resources Institute Steven Keating Art Director Agricultural Communications Visit our Web site at http://twri.tamu.edu for more information. On the cover: Caddo Lake Photo courtesy of Texas Parks and Wildlife Department ? 2005 Message from...

  6. txH2O: Volume 5, Number 1 (Complete) 

    E-Print Network [OSTI]

    Texas Water Resources Institute

    2009-01-01

    Plant near Brownsville. Sturdi- vant said their specific results are only appli- cable to the Southmost facility, but do provide useful information regarding life-cycle costs for other desalination facilities. ?Though the case study provides a...

  7. High Performance Builder Spotlight: GreenCraft, Lewisville, TX

    SciTech Connect (OSTI)

    2011-01-01

    In October and November 2009, the TimberCreek Zero Energy House in Lewisville, Texas, opened as a Building America Demonstration House. The 2,538-foot,three-bedroom, 2½-bath custom-built home showed a home energy rating score (HERS) of 56 without the solar photovoltaics and a HERS score of 1 with PV.

  8. TX, RRC District 3 Onshore Coalbed Methane Proved Reserves, Reserves...

    U.S. Energy Information Administration (EIA) Indexed Site

    71 47 2005-2013 Adjustments 0 0 0 81 -17 2009-2013 Revision Increases 0 0 0 0 0 2009-2013 Revision Decreases 0 0 0 0 0 2009-2013 Sales 0 0 0 0 0 2009-2013 Acquisitions 0 0 0 0 0...

  9. TX, RRC District 10 Coalbed Methane Proved Reserves, Reserves...

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    8 7 2005-2013 Adjustments 0 0 0 9 0 2009-2013 Revision Increases 0 0 0 0 0 2009-2013 Revision Decreases 0 0 0 0 0 2009-2013 Sales 0 0 0 0 0 2009-2013 Acquisitions 0 0 0 0 0...

  10. TX, RRC District 4 Onshore Coalbed Methane Proved Reserves, Reserves...

    U.S. Energy Information Administration (EIA) Indexed Site

    1 1 2005-2013 Adjustments 0 0 0 1 0 2009-2013 Revision Increases 0 0 0 0 0 2009-2013 Revision Decreases 0 0 0 0 0 2009-2013 Sales 0 0 0 0 0 2009-2013 Acquisitions 0 0 0 0 0...

  11. TX, RRC District 2 Onshore Coalbed Methane Proved Reserves, Reserves...

    U.S. Energy Information Administration (EIA) Indexed Site

    1 2 2005-2013 Adjustments 0 0 0 1 1 2009-2013 Revision Increases 0 0 0 0 0 2009-2013 Revision Decreases 0 0 0 0 0 2009-2013 Sales 0 0 0 0 0 2009-2013 Acquisitions 0 0 0 0 0...

  12. txH20: Volume 6, Number 2 (Complete) 

    E-Print Network [OSTI]

    Wythe, Kathy

    2011-01-01

    Damage Assessment response teams had documented ?,??? visibly oiled dead birds, ?,??? visibly oiled live birds, ?? visibly oiled dead sea turtles, and ??? visibly oiled live sea turtles. A major concern a?er the spill was the possibility of the oil... (Environmental Chemical Sciences) grant, also included scientists from Louisiana State University, Georgia Tech, and the Louisiana Universities Marine Consortium. A?er returning to the marshes in September ????, he said that areas he examined around...

  13. txH2O: Volume 6, Number 2 (Complete) 

    E-Print Network [OSTI]

    Texas Water Resources Institute

    2011-01-01

    Damage Assessment response teams had documented ?,??? visibly oiled dead birds, ?,??? visibly oiled live birds, ?? visibly oiled dead sea turtles, and ??? visibly oiled live sea turtles. A major concern a?er the spill was the possibility of the oil... (Environmental Chemical Sciences) grant, also included scientists from Louisiana State University, Georgia Tech, and the Louisiana Universities Marine Consortium. A?er returning to the marshes in September ????, he said that areas he examined around...

  14. txH20: Volume 7, Number 2 (Complete) 

    E-Print Network [OSTI]

    Wythe, Kathy

    2012-01-01

    this opportunity to make substantial changes to water policy. He cited major changes made to water planning regulations a?er previous droughts, including methods of integrating di?erent water laws into a prior appropriations system a?er the ????s drought... to improve. Dr. Todd Vo?eler, executive manager of science, intergovernmental relations and policy for the Guadalupe-Blanco River Authority, said the state no longer has the surplus water it had from the reservoirs built a?er the drought of record...

  15. txH20: Volume 7, Number 3 (Complete) 

    E-Print Network [OSTI]

    Wythe, Kathy

    2012-01-01

    to be there to provide answers and to interpret the research necessary to get the job done.? Q: Does the recent drought make the center more important? A: Water issues now, a?er several years of drought, are more important. Because of its water challenges, San... management,? said Con Mims, executive director of the Nueces River Authority and steering commi?ee chair. A?er four years of once- or twice-monthly meetings, each with more than ?? a?endees, members dra?ed, developed and molded a habitat conservation...

  16. txH2O: Volume 2, Number 2 (Complete) 

    E-Print Network [OSTI]

    Texas Water Resources Institute

    2006-01-01

    Mesquite and juniper can be beneficially utilized for gasification and combustion applications. Torrefaction has been considered to be one of the thermal pretreatment options to improve the chemical (e.g. heat content) and ...

  17. Alamo, TX Natural Gas Imports by Pipeline from Mexico

    U.S. Energy Information Administration (EIA) Indexed Site

    3,678 27,479 48,850 72,039 76,111 78,866 1998-2014 Pipeline Prices 3.95 4.50 4.10 2.86 3.81 4.63 1998...

  18. txH2O: Volume 5, Number 2 (Complete) 

    E-Print Network [OSTI]

    Texas Water Resources Institute

    2009-01-01

    summe r keep it o n 72? at n ight and 8 2? during the day. ? Chan ge air filt ers once a month or rinse if w ashable. I nsert air filter corr ectly. ? For w indow un its, look a t the size of the ro om and n umber of people.... In and ar ound the kitchen ? Dishw asher ? R un bleach through the dishw asher to c lean the d rain. ? Bakin g ? Use ce ramic or g lass pans because they bake food qui cker than metal pans. ? Durin g summe r ? Cook with the m...

  19. Jonathan Frome 1242 Dumont Dr., Richardson, TX, 75093

    E-Print Network [OSTI]

    O'Toole, Alice J.

    ." In The Routledge Companion to Philosophy and Film, edited by Paisley Livingston and Carl Plantinga, 334­343. New

  20. HASE'07 Panel 4a Dallas, TX Achieving High Assurance

    E-Print Network [OSTI]

    Tian, Jeff

    . Ishikawa's fishbone diagrams. FTA: Fault tree analysis. ETA: Event tree analysis. FMEA: Failure mode

  1. TX, RRC District 5 Shale Gas Proved Reserves, Reserves Changes...

    Gasoline and Diesel Fuel Update (EIA)

    13,691 16,032 19,747 11,513 13,592 2007-2013 Adjustments 657 105 233 -516 -70 2009-2013 Revision Increases 928 643 3,094 30 2,922 2009-2013 Revision Decreases 587 405 1,405 6,895...

  2. TX, RRC District 8 Shale Gas Proved Reserves, Reserves Changes...

    Gasoline and Diesel Fuel Update (EIA)

    48 24 90 61 583 649 2007-2013 Adjustments -1 53 -79 249 -21 2009-2013 Revision Increases 2 20 45 19 121 2009-2013 Revision Decreases 22 0 12 47 112 2009-2013 Sales 0 0 0 19 50...

  3. TX, RRC District 1 Shale Gas Proved Reserves, Reserves Changes...

    Gasoline and Diesel Fuel Update (EIA)

    2 435 1,564 5,123 8,340 7,357 2007-2013 Adjustments 5 8 0 47 315 2009-2013 Revision Increases 1 322 2,141 1,852 1,083 2009-2013 Revision Decreases 0 251 48 1,272 2,818 2009-2013...

  4. TX, RRC District 6 Shale Gas Proved Reserves, Reserves Changes...

    Gasoline and Diesel Fuel Update (EIA)

    73 1,161 4,381 6,584 4,172 4,633 2007-2013 Adjustments 40 1,968 26 -225 564 2009-2013 Revision Increases 422 1,206 2,322 999 513 2009-2013 Revision Decreases 8 1,319 1,860 2,907...

  5. TX, RRC District 3 Onshore Shale Gas Proved Reserves, Reserves...

    Gasoline and Diesel Fuel Update (EIA)

    0 0 1 6 24 2007-2013 Adjustments 0 0 1 1 -3 2009-2013 Revision Increases 0 0 0 1 2 2009-2013 Revision Decreases 0 0 0 0 0 2009-2013 Sales 0 0 0 0 4 2009-2013 Acquisitions 0 0 0 2 0...

  6. TX, RRC District 4 Onshore Shale Gas Proved Reserves, Reserves...

    Gasoline and Diesel Fuel Update (EIA)

    78 565 2,611 3,091 4,377 2007-2013 Adjustments 53 0 185 300 592 2009-2013 Revision Increases 0 66 792 253 174 2009-2013 Revision Decreases 0 12 295 1,160 819 2009-2013 Sales 0 0 75...

  7. TX, RRC District 9 Shale Gas Proved Reserves, Reserves Changes...

    Gasoline and Diesel Fuel Update (EIA)

    10,756 12,573 10,276 9,260 9,580 2007-2013 Adjustments 179 533 42 -483 378 2009-2013 Revision Increases 580 1,044 3,005 200 1,092 2009-2013 Revision Decreases 469 191 5,864...

  8. TX, RRC District 2 Onshore Shale Gas Proved Reserves, Reserves...

    Gasoline and Diesel Fuel Update (EIA)

    2010 2011 2012 2013 View History Proved Reserves as of Dec. 31 395 1,692 4,743 5,595 2010-2013 Adjustments 6 237 494 40 2010-2013 Revision Increases 6 388 326 839 2010-2013...

  9. TX, RRC District 10 Shale Gas Proved Reserves, Reserves Changes...

    Gasoline and Diesel Fuel Update (EIA)

    0 0 0 0 37 37 2007-2013 Adjustments 0 0 -1 11 6 2009-2013 Revision Increases 0 0 0 31 0 2009-2013 Revision Decreases 0 0 0 0 0 2009-2013 Sales 0 0 0 0 1 2009-2013 Acquisitions 0 0...

  10. Geophysical Mapping of Lost Historical Sites: Brenham, TX 

    E-Print Network [OSTI]

    Stanford, Charles

    2014-09-17

    of distance cm Centimeters – measurement of distance m 2 Squared Meters – measurement of area kHz Kilohertz, 1000 hertz – measurement of frequency MHz Megahertz, 10 6 hertz GHz Gigahertz, 10 9 hertz nT nanoTeslas... battery pack and is responsible for recording and storing of all data. Typically measurements of the geomagnetic field range from 45,000 to 50,000 nanoTeslas (nT), the G-858 magnetometer is able to measure the magnetic field with a precision of 0.1 n...

  11. txH2O: Volume 9, Number 1 (Complete) 

    E-Print Network [OSTI]

    Wythe, Kathy

    2014-01-01

    are spring-fed, so increased pumping of groundwater will affect spring flows and consequently water bodies. Groundwater management is no easy task In Texas, surface water is legally considered public property and state-owned, while ground- water... the construction of wells and the licensing requirements for water well drillers and pump installers. Water well drillers must submit drilling logs and other required information to TDLR and TWBD. The completion and plugging of such wells must comply with TDLR...

  12. Freeport, TX Liquefied Natural Gas Exports to Brazil (Million...

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    Decade Year-0 Year-1 Year-2 Year-3 Year-4 Year-5 Year-6 Year-7 Year-8 Year-9 2000's 0 0 0 2010's 0 2,581 8,142 0 2,664...

  13. ,"TX, RRC District 10 Lease Condensate Proved Reserves, Reserve...

    U.S. Energy Information Administration (EIA) Indexed Site

    Lease Condensate Proved Reserves, Reserve Changes, and Production" ,"Click worksheet name or tab at bottom for data" ,"Worksheet Name","Description"," Of Series","Frequency","Late...

  14. ,"TX, RRC District 10 Crude Oil plus Lease Condensate Proved...

    U.S. Energy Information Administration (EIA) Indexed Site

    Crude Oil plus Lease Condensate Proved Reserves" ,"Click worksheet name or tab at bottom for data" ,"Worksheet Name","Description"," Of Series","Frequency","Latest Data for"...

  15. ,"TX, RRC District 1 Lease Condensate Proved Reserves, Reserve...

    U.S. Energy Information Administration (EIA) Indexed Site

    Lease Condensate Proved Reserves, Reserve Changes, and Production" ,"Click worksheet name or tab at bottom for data" ,"Worksheet Name","Description"," Of Series","Frequency","Late...

  16. ,"TX, RRC District 5 Lease Condensate Proved Reserves, Reserve...

    U.S. Energy Information Administration (EIA) Indexed Site

    Lease Condensate Proved Reserves, Reserve Changes, and Production" ,"Click worksheet name or tab at bottom for data" ,"Worksheet Name","Description"," Of Series","Frequency","Late...

  17. ,"TX, RRC District 3 Onshore Lease Condensate Proved Reserves...

    U.S. Energy Information Administration (EIA) Indexed Site

    Lease Condensate Proved Reserves, Reserve Changes, and Production" ,"Click worksheet name or tab at bottom for data" ,"Worksheet Name","Description"," Of Series","Frequency","Late...

  18. ,"TX, RRC District 8A Lease Condensate Proved Reserves, Reserve...

    U.S. Energy Information Administration (EIA) Indexed Site

    Lease Condensate Proved Reserves, Reserve Changes, and Production" ,"Click worksheet name or tab at bottom for data" ,"Worksheet Name","Description"," Of Series","Frequency","Late...

  19. ,"TX, RRC District 4 Onshore Crude Oil plus Lease Condensate...

    U.S. Energy Information Administration (EIA) Indexed Site

    Crude Oil plus Lease Condensate Proved Reserves" ,"Click worksheet name or tab at bottom for data" ,"Worksheet Name","Description"," Of Series","Frequency","Latest Data for"...

  20. ,"TX, RRC District 7B Lease Condensate Proved Reserves, Reserve...

    U.S. Energy Information Administration (EIA) Indexed Site

    Lease Condensate Proved Reserves, Reserve Changes, and Production" ,"Click worksheet name or tab at bottom for data" ,"Worksheet Name","Description"," Of Series","Frequency","Late...