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Note: This page contains sample records for the topic "human skin model" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


1

Assessment of penetration of quantum dots through in vitro and in vivo human skin using the human skin equivalent model and the tape stripping method  

SciTech Connect (OSTI)

Quantum dots (QDs) are rapidly emerging as an important class of nanoparticles (NPs) with potential applications in medicine. However, little is known about penetration of QDs through human skin. This study investigated skin penetration of QDs in both in vivo and in vitro human skin. Using the tape stripping method, this study demonstrates for the first time that QDs can actually penetrate through the stratum corneum (SC) of human skin. Transmission electron microscope (TEM) and energy diverse X-ray (EDX) analysis showed accumulation of QDs in the SC of a human skin equivalent model (HSEM) after dermal exposure to QDs. These findings suggest possible transdermal absorption of QDs after dermal exposure over a relatively long period of time.

Jeong, Sang Hoon; Kim, Jae Hwan; Yi, Sang Min [Laboratory of Cell Signaling and Nanomedicine, Department of Dermatology and Division of Brain Korea 21 Project for Biomedical Science, Korea University College of Medicine, Seoul (Korea, Republic of)] [Laboratory of Cell Signaling and Nanomedicine, Department of Dermatology and Division of Brain Korea 21 Project for Biomedical Science, Korea University College of Medicine, Seoul (Korea, Republic of); Lee, Jung Pyo; Kim, Jin Ho; Sohn, Kyung Hee; Park, Kui Lea [National Institute of Toxicological Research, Seoul (Korea, Republic of)] [National Institute of Toxicological Research, Seoul (Korea, Republic of); Kim, Meyoung-Kon [Department of Biochemistry and Molecular Biology, Korea University College of Medicine, Seoul (Korea, Republic of)] [Department of Biochemistry and Molecular Biology, Korea University College of Medicine, Seoul (Korea, Republic of); Son, Sang Wook, E-mail: skin4u@korea.ac.kr [Laboratory of Cell Signaling and Nanomedicine, Department of Dermatology and Division of Brain Korea 21 Project for Biomedical Science, Korea University College of Medicine, Seoul (Korea, Republic of)

2010-04-09T23:59:59.000Z

2

Low dose and bystander responses in a 3-D human skin model  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

and bystander responses in a 3-D human skin model. and bystander responses in a 3-D human skin model. Sally A. Amundson and Alexandre Mezentsev Columbia University Medical Center, Center for Radiological Research, New York, NY 10032 Significant structural abnormalities develop within several days of exposure of the 3-dimensional normal human skin tissue model EPI-200 (MatTek) to high or low doses of low LET radiation. Disruption of the basal layer occurs following high radiation doses, and premature cornification is evident after both high and low dose exposures. In bystander tissue that is near irradiated portions of the tissue, but is not itself irradiated, we also observe premature cornification, increased apoptosis and micronucleus formation. Changes in global gene expression also occur

3

Low dose and bystander responses in a 3-D human skin model  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

and bystander responses in a 3-D human skin model and bystander responses in a 3-D human skin model Sally A. Amundson Columbia University Medical Center Abstract Significant structural abnormalities develop within several days of exposure of the 3-dimensional normal human skin tissue model EPI-200 (MatTek) to high or low doses of low LET radiation. Disruption of the basal layer occurs following high radiation doses, and premature cornification is evident after both high and low dose exposures. In bystander tissue that is near irradiated portions of the tissue, but is not itself irradiated, we also observe premature cornification, increased apoptosis and micronucleus formation. Changes in global gene expression also occur in both directly irradiated and bystander EPI-200 tissue. Although the unfolding over time

4

Thermal Modeling and Experimental Validation of Human Hair and Skin Heated by Broadband Light  

E-Print Network [OSTI]

distribution within the hair follicle is highly non-uniform: the minimum temperature occurs at the follicle Sun, PhD,1 Alex Chaney,1 Robert Anderson, PhD,2 and Guillermo Aguilar, PhD 1 * 1 Department:(a)determinetheoveralleffectofPPxonskinhumidi- tyandassociatedskinopticalproperties,and;(b)developaPT numerical model to study the spatial and temporal hair and skin temperature

Aguilar, Guillermo

5

DNA damage and repair in human skin in situ  

SciTech Connect (OSTI)

Understanding the molecular and cellular origins of sunlight-induced skin cancers in man requires knowledge of the damages inflicted on human skin during sunlight exposure, as well as the ability of cells in skin to repair or circumvent such damage. Although repair has been studied extensively in procaryotic and eucaryotic cells - including human cells in culture - there are important differences between repair by human skin cells in culture and human skin in situ: quantitative differences in rates of repair, as well as qualitative differences, including the presence or absence of repair mechanisms. Quantitation of DNA damage and repair in human skin required the development of new approaches for measuring damage at low levels in nanogram quantities of non-radioactive DNA. The method allows for analysis of multiple samples and the resulting data should be related to behavior of the DNA molecules by analytic expressions. Furthermore, it should be possible to assay a variety of lesions using the same methodology. The development of new analysis methods, new technology, and new biochemical probes for the study of DNA damage and repair are described. 28 refs., 4 figs.

Sutherland, B.M.; Gange, R.W.; Freeman, S.E.; Sutherland, J.C.

1987-01-01T23:59:59.000Z

6

E-Print Network 3.0 - aged human skin Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

skin-color to track human body. In this paper, we discuss... on human faces. Using skin color as a feature ... Source: Yang, Jie - Human Computer Interaction Institute & School...

7

E-Print Network 3.0 - aging human skin Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

skin-color to track human body. In this paper, we discuss... on human faces. Using skin color as a feature ... Source: Yang, Jie - Human Computer Interaction Institute & School...

8

E-Print Network 3.0 - adult human skin Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

and push-ups respiration, sweating, changes in skin... ;Future of PETMAN usage in enviroment dangerousto humans transformation into a free standing, self Source: Takac,...

9

Simulation of Electron Beam Irradiation of a Skin Tissue Model  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Simulation of Electron Beam Irradiation of a Skin Tissue Model Simulation of Electron Beam Irradiation of a Skin Tissue Model John Miller Washington State University Tri-Cities Abstract Monte Carlo simulations of electrons stopping in liquid water are being used to model electronbeam irradiation of the full-thickness (FT) EpiDermTM skin model (MatTek, Ashland, VA). This 3D tissue model has a fully developed basement membrane separating an epidermal layer of keratinocytes from a dermal layer of fibroblasts embedded in collagen. The simulations have shown the feasibility of exposing the epidermal layer to low linear-energy-transfer (LET) radiation in the presence of a non-irradiated dermal layer (Miller et al. 2011). The variableenergy electron microbeam at PNNL (Sowa et al. 2005) was used as a model of device characteristics and

10

Skin strain analysis software for the study of human skin deformation  

E-Print Network [OSTI]

Skin strain studies have never been conducted in a precise and automated fashion. Previous in vivo strain investigations have been labor intensive and the data resolution was extremely limited such that their results were ...

Marecki, Andrew T. (Andrew Thomas)

2012-01-01T23:59:59.000Z

11

Simulation of Electron Beam Irradiation of a Skin Tissue Model  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Electron Beam Irradiation of a Skin Tissue Model Electron Beam Irradiation of a Skin Tissue Model John Miller 1 , Seema Varma 1 , William Chrisler 2 , Xihai Wang 2 and Marianne Sowa 2 1 Washington State University Tri-Cities, Richland, WA 2 Pacific Northwest National Laboratory, Richland, WA Monte Carlo simulations of electrons stopping in liquid water are being used to model electron- beam irradiation of the full-thickness (FT) EpiDerm TM skin model (MatTek, Ashland, VA). This 3D tissue model has a fully developed basement membrane separating an epidermal layer of keratinocytes from a dermal layer of fibroblasts embedded in collagen. The simulations have shown the feasibility of exposing the epidermal layer to low linear-energy-transfer (LET) radiation in the presence of a non-irradiated dermal layer (Miller et al. 2011). The variable-

12

Procter & Gamble and Temple University scientists model skin...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

industry. For example, a better understanding of skin permeation could enable the pharmaceutical industry to advance drugs that are administered through the skin. P&G,...

13

E-Print Network 3.0 - alternative skin model Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

by the limb, and a simpli- fied model of the anatomy under the skin. Users interactively paint weights... anatomic structures. Having modeled the contributions of passive ......

14

Solar UV radiation reduces the barrier function of human skin  

Science Journals Connector (OSTI)

Solar UV radiation reduces the barrier function...Stanford, CA 94305 The ubiquitous presence of solar UV radiation in human life is essential for...defense against environmental exposures like solar UV radiation, and its effects on UV targets...

Krysta Biniek; Kemal Levi; Reinhold H. Dauskardt

2012-01-01T23:59:59.000Z

15

Identification of novel ionizing radiation signaling targets in reconstituted human skin  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

of novel ionizing radiation signaling targets in reconstituted human skin of novel ionizing radiation signaling targets in reconstituted human skin Feng Yang, Katrina M. Waters, Bobbie-Jo Webb-Robertson, Lye-Meng Markillie, Rachel M. Wirgau, Shawna M. Hengel, Ljiljana Pasa-Tolic, and David L. Stenoien. Pacific Northwest National Laboratory Our focus has been on identifying the early events that occur after low dose ionizing radiation exposure that precede and often regulate downstream events such as altered transcription, protein secretion and epigenetic regulation. Phosphorylation is one of the earliest detectible events that occurs following radiation exposure and plays important roles in multiple biological pathways including DNA damage repair, transcription, apoptosis, and cell cycle progression. Very robust

16

Modelling and simulation of skin-stretch-caused motion artefacts in single-channel ECG signal  

E-Print Network [OSTI]

Modelling and simulation of skin-stretch-caused motion artefacts in single-channel ECG signal in better understanding of artefacts in ECG and in developing model-based techniques for cleaning or interpreting noisy ECG signals. This work com- bines existing experimental results from the field of skin

Hamburg,.Universität

17

Development of a membrane impregnated with a poly(dimethylsiloxane)/poly(ethylene glycol) copolymer for a high-throughput screening of the permeability of drugs, cosmetics, and other chemicals across the human skin  

Science Journals Connector (OSTI)

Abstract We aimed to develop a high-throughput screening (HTS) system for preliminary predictions of human skin permeability by using an artificial membrane that can mimic the permeation behaviour of lipophilic and hydrophilic compounds across the human skin. In this study, we synthesized a copolymer containing poly(dimethylsiloxane) (PDMS) and poly(ethylene glycol) (PEG) 6000 and impregnated it onto a supportive membrane filter to prepare a PDMS/PEG 6000 copolymer-impregnated membrane. In addition, we synthesized another polymer without PEG units and used it to prepare an impregnated membrane for determining the role of PEG 6000 units in the PDMS/PEG 6000 copolymer-impregnated membrane. The permeation characteristics of the impregnated membranes were evaluated on the basis of the permeability coefficients of 12 model compounds with different lipophilicities, by using a 2-chamber diffusion cell, and these permeability coefficients were compared with those across the human skin. We obtained a good correlation between the permeability coefficients across the PDMS/PEG 6000 copolymer-impregnated membrane and human skin. Further, we evaluated the permeation characteristics of a 96-well plate model of the PDMS/PEG 6000 copolymer by using 6 model compounds. We obtained an ideal correlation between the permeability coefficients across the PDMS/PEG 6000 copolymer using a 96-well plate and those across the human skin. Thus, the PDMS/PEG 6000 copolymer would be a good candidate for preliminary evaluation of the permeability of lipophilic and hydrophilic compounds across the human skin.

Ryotaro Miki; Yasuna Ichitsuka; Takumi Yamada; Soichiro Kimura; Yuya Egawa; Toshinobu Seki; Kazuhiko Juni; Hideo Ueda; Yasunori Morimoto

2015-01-01T23:59:59.000Z

18

Numerical modeling of a wing skin peen forming process  

Science Journals Connector (OSTI)

For many years shot peering has been used to provide fatigue resistance and form to airplane wing skins at the Boeing Commercial Airplane Company. In this process, ... to replicate the shot peening process used a...

R. D. VanLuchene; E. J. Cramer

1996-12-01T23:59:59.000Z

19

In vivo evaluation of Fe in human skin employing X?Ray Fluorescence Methodology (XRF)  

Science Journals Connector (OSTI)

Recent technological improvements allow the method of in vivo XRF to provide useful sensibility for diagnostics or monitoring in biomedical applications. In cases of hereditary sanguine disorders as the ??thalassaemia or a genetic disorder like Haemochromatosis there is a high concentration of elements as Fe Zn and Cu in the skin and internal organs due to the treatment of those abnormalities or due to the own dysfunction caused by the disease. The levels of Fe related to the patient bearers of the ??thalassaemia are determined at the moment measuring a protein in the sanguine current called ferritin. The monitoring of the protein is ineffective in several situations such as when the patient suffers any disturbance of health. Nowadays the main forms of measuring the levels of those metals through hepatic storage are the biopsy of the liver that is invasive and potentially dangerous presenting a rate of mortality of 0.1% and by means of magnetic susceptibilities that employs a quantum superconductor which is highly expensive and there are only three main world centers with this equipment This work investigates the use of a Si PIN?diode detector and a 238Pu source (13 and 17keV; 13%; 95.2mCi; 86y) for the measurement of Fe skin levels compatible with those associated to the disease ??thalassaemia. XRF spectra were analyzed using a set of AXIL?WinQXAS programs elaborated and disseminated by the IAEA. The determination coefficient of the calibration model (sensitivity curve) was 0.97. Measurements on skin phantoms containing concentrations of Fe in the range from 10 to 150 parts per million (ppm) indicate that we are able to detect Fe at levels of the order of 15ppm using monitoring periods of 50 seconds and skin entrance dose less than 10 mSv The literature reports skin Fe levels from 15.0 to 60.0 ppm in normal persons and from 70 to 150 ppm in thalassaemics patients. So the employed methodology allows the measurement of the skin Fe concentration.

M. Estevam; C. R. Appoloni

2007-01-01T23:59:59.000Z

20

Skin Evolution  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Skin Evolution Skin Evolution Name: Olga Location: N/A Country: N/A Date: N/A Question: Do you think it is possible that our ancestors were actually black, and that a gene mutation for an enzyme in the metabollic pathway of melanin meant that not enough melanin was produced some of us ended up with white skin. Primitive apes have black skin, and we evolved from them, so doesn't this mean that humans orginally had black skin??? Replies: Most likely, yes, humans probably evolved from dark-skinned ancestors. I will take issue, however, with your statement that "primitive apes have black skin;" we can't say that for absolute certain, because we have no primitive apes to compare to. All we have now are modern apes. All modern apes - homo sapiens, pan troglodytes, gorilla gorilla - are highly, probably equally, evolved. (One could make an argument that homo sapiens is in many ways more generalized - note the generalized dentition, fragile skeleton, etc. - than other modern apes, and thus could be said to be more primitive.) As far as that goes, the only modern apes with white skin I know of are a color variant of homo sapiens.

Note: This page contains sample records for the topic "human skin model" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


21

Fisetin inhibits human melanoma cell growth through direct binding to p70S6K and mTOR: Findings from 3-D melanoma skin equivalents and computational modeling  

Science Journals Connector (OSTI)

Abstract The incidence of melanoma continues to rise. Inspite of treatment advances, the prognosis remains grim once the disease has metastasized, emphasizing the need to explore additional therapeutic strategies. One such approach is through the use of mechanism-based dietary intervention. We previously showed that the flavonoid fisetin inhibits melanoma cell proliferation, in vitro and in vivo. Here, we studied fisetin-mediated regulation of kinases involved in melanoma growth and progression. Time-course analysis in 3-D melanoma constructs that transitioned from radial to vertical growth showed that fisetin treatment resulted in significant decrease in melanocytic lesions in contrast to untreated controls that showed large tumor nests and invading disseminated cells. Further studies in melanoma cultures and mouse xenografts showed that fisetin-mediated growth inhibition was associated with dephosphorylation of AKT, mTOR and p70S6K proteins. In silico modeling indicated direct interaction of fisetin with mTOR and p70S6K with favorable free energy values. These findings were validated by cell-free competition assays that established binding of fisetin to p70S6K and mTOR while little affinity was detected with AKT. Kinase activity studies reflected similar trend with % inhibition observed for p70S6K and mTOR at lower doses than AKT. Our studies characterized, for the first time, the differential interactions of any botanical agent with kinases involved in melanoma growth and demonstrate that fisetin inhibits mTOR and p70S6K through direct binding while the observed inhibitory effect of fisetin on AKT is mediated indirectly, through targeting interrelated pathways.

Deeba N. Syed; Jean-Christopher Chamcheu; Mohammad Imran Khan; Mario Sechi; Rahul K. Lall; Vaqar M. Adhami; Hasan Mukhtar

2014-01-01T23:59:59.000Z

22

E-Print Network 3.0 - adult human dermis Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Engineering 3 Developing a predictive model of human skin colouring Symon D'Oyly Cotton Summary: Developing a predictive model of human skin colouring Symon D'Oyly Cotton Ela...

23

A soil moisture assimilation scheme using satellite-retrieved skin temperature in meso-scale weather forecast model  

Science Journals Connector (OSTI)

A thermodynamically consistent soil moisture assimilation scheme for clear sky and snow free conditions has been developed for the meso-scale modeling system in the Arctic region by using satellite-derived skin temperatures. Parallel control and sensitivity modeling experiments were designed and their results demonstrated that the assimilation scheme successfully improves the soil moistures that were deliberately perturbed initially, indicating capability of the scheme to correct bias in the soil moisture initialization. Moreover, the resultant benefit of this assimilation scheme does not only lie in the improvement of soil moisture; the skin temperature also consequently exhibits improvements in a thermodynamic consistency. A real application of the assimilation scheme with satellite-retrieved skin temperature exhibited noticeable positive impacts on the modeling simulation and weather forecast; the model obviously captured meso-scale features of soil moistures as well as the skin temperatures. The warming tendency bias in original model simulations was removed to a considerable extent by this assimilation scheme.

Jing Zhang; Xiangdong Zhang

2010-01-01T23:59:59.000Z

24

Gaussian-function-based deconvolution method to determine the penetration ability of petrolatum oil into in vivo human skin using confocal Raman microscopy  

Science Journals Connector (OSTI)

Human skin pre-treated with petrolatum was analyzed in vivo using confocal Raman microscopy in order to determine the penetration depth of the oil into the skin. The broad Raman peak (2820–3030?cm?1) measured in vivo on human skin in the high wavenumber region exhibits two prominent main Raman peaks at 2880?cm?1 and 2935?cm?1 that originated from cutaneous lipids and keratin and two main peak shoulders at 2850?cm?1 and 2980?cm?1 that originated from lipids and keratin, respectively. Topical application of petrolatum oil onto the skin gives rise to an increase of the intensity of the broad lipid–keratin Raman peak (2820–3030?cm?1). Herewith, not only the intensity of the lipid part but also of the keratin part is increased, making the normalization to keratin and the determination of the petrolatum penetration profile erroneous. To solve this problem, the Gaussian-function-based deconvolution method is introduced in analyzing the Raman spectrum of the lipid–keratin peak and the least square method is applied for analyzing the petrolatum penetration profile. Results obtained in vivo show that the petrolatum oil does not penetrate deeper than 10?µm into intact human skin.

Chun-Sik Choe; Jürgen Lademann; Maxim E Darvin

2014-01-01T23:59:59.000Z

25

Learning Human Motion Models Bulent Tastan  

E-Print Network [OSTI]

Learning Human Motion Models Bulent Tastan Department of EECS University of Central Florida Orlando In this summary, I provide an overview of my disserta- tion work on learning human motion models from trajectory) pursuing opponents. Human Tracking One of the most powerful constraints governing many ac- tivity

Sukthankar, Gita Reese

26

Deformable human body model development  

SciTech Connect (OSTI)

This is the final report of a three-year, Laboratory Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). A Deformable Human Body Model (DHBM) capable of simulating a wide variety of deformation interactions between man and his environment has been developed. The model was intended to have applications in automobile safety analysis, soldier survivability studies and assistive technology development for the disabled. To date, we have demonstrated the utility of the DHBM in automobile safety analysis and are currently engaged in discussions with the U.S. military involving two additional applications. More specifically, the DHBM has been incorporated into a Virtual Safety Lab (VSL) for automobile design under contract to General Motors Corporation. Furthermore, we have won $1.8M in funding from the U.S. Army Medical Research and Material Command for development of a noninvasive intracranial pressure measurement system. The proposed research makes use of the detailed head model that is a component of the DHBM; the project duration is three years. In addition, we have been contacted by the Air Force Armstrong Aerospace Medical Research Laboratory concerning possible use of the DHBM in analyzing the loads and injury potential to pilots upon ejection from military aircraft. Current discussions with Armstrong involve possible LANL participation in a comparison between DHBM and the Air Force Articulated Total Body (ATB) model that is the current military standard.

Wray, W.O.; Aida, T.

1998-11-01T23:59:59.000Z

27

Asymmetric nuclear matter and neutron-skin in extended relativistic mean field model  

E-Print Network [OSTI]

The density dependence of the symmetry energy, instrumental in understanding the behaviour of the asymmetric nuclear matter, is investigated within the extended relativistic mean field (ERMF) model which includes the contributions from the self and mixed interaction terms for the scalar-isoscalar ($\\sigma$), vector-isoscalar ($\\omega$) and vector-isovector ($\\rho$) mesons upto the quartic order. Each of the 26 different parameterizations of the ERMF model employed are compatible with the bulk properties of the finite nuclei. The behaviour of the symmetry energy for several parameter sets are found to be consistent with the empirical constraints on them as extracted from the analyses of the isospin diffusion data. The neutron-skin thickness in the $^{208}$Pb nucleus for these parameter sets of the ERMF model lie in the range of $\\sim 0.20 - 0.24$ fm which is in harmony with the ones predicted by the Skyrme Hartree-Fock model. We also investigate the role of various mixed interaction terms which are crucial for the density dependence of the symmetry energy.

B. K. Agrawal

2010-03-17T23:59:59.000Z

28

Improvement of the equivalent sphere model for better estimates of skin or eye dose in space radiation environments  

E-Print Network [OSTI]

sphere Radiation transport a b s t r a c t It is often useful to get a quick estimate of the dose or dose drastically improves the accuracy of the estimates of dose and dose equivalent in space radiation environmentsImprovement of the equivalent sphere model for better estimates of skin or eye dose in space

Lin, Zi-wei

29

Skin flicks  

E-Print Network [OSTI]

The written and artistic part of this thesis are both separated into the two categories of "SKIN" and "FLICKS". The Artistic part of my thesis consists of five artificial skins made on my body, and a series of video tapes ...

Orth, Margaret A. (Margaret Ann), 1964-

1993-01-01T23:59:59.000Z

30

A Muscular Rig for Smooth Skinning in Autodesk Maya.  

E-Print Network [OSTI]

?? The limitations of the default skinning methods in Autodesk Maya can be compensated for when seeking realistic skin deformations of a human being. The… (more)

Björkman, Pontus

2007-01-01T23:59:59.000Z

31

Mesh Resolution Augmentation using 3D Skin Bank Won-Sook Lee*  

E-Print Network [OSTI]

on a 100-micron resolution scan of plaster cast molds of the actors' faces. Human skin was modeled using, as shown in Figure 1. Each individual is presented with closed eyes and mouth due to the use of plaster

Lee, WonSook

32

Sverdlovsk revisited: Modeling human inhalation anthrax  

Science Journals Connector (OSTI)

...mentioned above. Models A1, A2, and D predict 44, 247...difficult during flu season, for...second day, with models A1, A2 and D predicting...the range of models that accurately predict the effects...epidemiology Disease Outbreaks Humans Inhalation...

Dean A. Wilkening

2006-01-01T23:59:59.000Z

33

Development and Investigation of Synthetic Skin Simulant Platform (3SP) in Friction Blister Applications  

E-Print Network [OSTI]

significant opportunity to take a similar approach of applying an engineering viewpoint to repeatably model the onset and formation of blisters on human skin. The authors have developed the Synthetic Skin Simulant Platform (3SP) to fulfill this role. The 3SP...

Guerra, Carlos

2012-02-14T23:59:59.000Z

34

Alzheimer's disease skin fibroblasts selectively express a bradykinin signaling pathway mediating  

E-Print Network [OSTI]

, is generated under conditions known as risk factors for AD, including stroke and traumatic head injury. BK B2 increases I/L B2 BK receptors in AD skin fibroblasts In established human fetal lung fibroblast models of protein kinase C (PKC). We now show that skin fibro- blasts of patients with AD developing around age 35

Steinbach, Joe Henry

35

UV-induced DNA Damage and Mutations in Hupki (Human p53 Knock-in) Mice Recapitulate p53 Hotspot Alterations in Sun-exposed Human Skin  

Science Journals Connector (OSTI)

...development of severely sun-damaged skin and...year (6 , 7) . Chronic sun exposure causes cumulative...spatial and statistical distribution of chromatin) and that...histologically normal, sun-damaged skin. Materials...and stored at room temperature. Vitamin A Clinical...

Jun-Li Luo; Wei-Min Tong; Jung-Hoon Yoon; Manfred Hergenhahn; Riita Koomagi; Qin Yang; Dominique Galendo; Gerd P. Pfeifer; Zhao-Qi Wang; and Monica Hollstein

2001-11-15T23:59:59.000Z

36

Skin melanin  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Skin melanin Skin melanin Name: Janae Lepir Location: N/A Country: N/A Date: N/A Question: How does the skin produce melanin? Replies: There are special cells in the skin called melanocytes. They synthesize melanin from an amino acid, tyrosine. (Amino acids make up proteins; there are about 20 different ones). Melanocytes can be stimulated by a hormone in the pituitary gland called melanocyte stimulating hormone (MSH). I don't know how much biology you've had, but melanocytes are derived from an interesting embryonic tissue called the neural crest, which also gives rise to a lot of different types of neurons, so embryologically melanocytes are related to neurons. If melanocytes become malignant, it becomes a very bad form of cancer, called melanoma (often called "skin cancer", although there are other forms of skin cancer).

37

Modelling the evolution of human trail systems  

Science Journals Connector (OSTI)

... Many human social phenomena, such as cooperation, the growth of settlements, traffic dynamics and pedestrian movement, appear to be accessible to mathematical descriptions that invoke self-organization. Here we ... be accessible to mathematical descriptions that invoke self-organization. Here we develop a model of pedestrian motion to explore the evolution of trails in urban green spaces such as parks. ...

Dirk Helbing; Joachim Keltsch; Péter Molnár

1997-07-03T23:59:59.000Z

38

Research on digital human model used in human factor simulation and evaluation of load carriage equipment  

Science Journals Connector (OSTI)

Data structure of the digital human model has been constructed for particularity demand of human factor evaluation of the load carriage system equipments. Anthropometry data of different percentage was obtained through regression calculation; Range of ... Keywords: digital human model, human factors, load carriage equipment, simulation

Dayong Dong; Lijing Wang; Xiugan Yuan; Shan Fu

2011-07-01T23:59:59.000Z

39

On the Use of Human Mobility Proxies for Modeling Epidemics  

E-Print Network [OSTI]

Human mobility is a key component of large-scale spatial-transmission models of infectious diseases. Correctly modeling and quantifying human mobility is critical for improving epidemic control, but may be hindered by data ...

Tizzoni, Michele

40

Skinlike Electronic Patch Takes Pulse, Promises New Human-Machine Integration: Scientific American http://www.scientificamerican.com/article.cfm?id=skin-electronic-patch[8/14/2011 6:02:32 AM  

E-Print Network [OSTI]

Skinlike Electronic Patch Takes Pulse, Promises New Human-Machine Integration: Scientific American http://www.scientificamerican.com/article.cfm?id=skin-electronic-patch[8/14/2011 6:02:32 AM] You might Show Most Commented Latest Posts by SA Editors Home » News » Skinlike Electronic Patch Takes Pulse

Rogers, John A.

Note: This page contains sample records for the topic "human skin model" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


41

Population Physiologically-Based Pharmacokinetic Modeling for the Human  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Population Physiologically-Based Pharmacokinetic Modeling for the Human Population Physiologically-Based Pharmacokinetic Modeling for the Human Lactational Transfer of PCB 153 with Consideration of Worldwide Human Biomonitoring Results Title Population Physiologically-Based Pharmacokinetic Modeling for the Human Lactational Transfer of PCB 153 with Consideration of Worldwide Human Biomonitoring Results Publication Type Journal Article Year of Publication 2008 Authors Redding, Laurel E., Michael D. Sohn, Thomas E. McKone, Shu-Li Wang, Dennis P. H. Hsieh, and Raymond S. H. Yang Journal Environmental Health Perspectives Volume 116 Issue 12 Pagination 1629-1634 Keywords bayesian inference, body burden, environmental chemistry, exposure & risk group, human milk biomonitoring, indoor environment department, lactational transfer, pcb 153, physiologically-based pharmacokinetic modeling, pollutant fate and transport modeling, poly-chlorinated biphenyls, reverse dosimetry

42

Neutron skins and neutron stars  

SciTech Connect (OSTI)

The neutron-skin thickness of heavy nuclei provides a fundamental link to the equation of state of neutron-rich matter, and hence to the properties of neutron stars. The Lead Radius Experiment ('PREX') at Jefferson Laboratory has recently provided the first model-independence evidence on the existence of a neutron-rich skin in {sup 208}Pb. In this contribution we examine how the increased accuracy in the determination of neutron skins expected from the commissioning of intense polarized electron beams may impact the physics of neutron stars.

Piekarewicz, J. [Department of Physics, Florida State University, Tallahassee, FL 32306-4350 (United States)

2013-11-07T23:59:59.000Z

43

The Efficacy of a Broad-spectrum Sunscreen to Protect Engineered Human Skin from Tissue and DNA Damage Induced by Solar Ultraviolet Exposure  

Science Journals Connector (OSTI)

...responses of the skin to solar UVR, 3 whereas photoaging...are diagnosed in Canada (2) . It has been...that a child born in Canada today has a 1 in...Skin exposure to solar UVR induces significant...Sunscreen Treatment and Solar UVR Irradiation...Bristol-Myers Squibb Co., Canada, were applied at...

Vickram Bissonauth; Régen Drouin; David L. Mitchell; Marc Rhainds; Joël Claveau; and Mahmoud Rouabhia

2000-10-01T23:59:59.000Z

44

Friction Induced Skin Tags  

E-Print Network [OSTI]

Duplantis KL, Jones BH. Friction blisters. Pathophysiology,Friction Induced Skin Tags Francisco Allegue MD 1 , Carmenetiopathogenic role for friction. Introduction Skin tags (

Allegue, Francisco; Fachal, Carmen; Pérez-Pérez, Lidia

2008-01-01T23:59:59.000Z

45

Fuzzy Control Strategies in Human Operator and Sport Modeling  

E-Print Network [OSTI]

The motivation behind mathematically modeling the human operator is to help explain the response characteristics of the complex dynamical system including the human manual controller. In this paper, we present two different fuzzy logic strategies for human operator and sport modeling: fixed fuzzy-logic inference control and adaptive fuzzy-logic control, including neuro-fuzzy-fractal control. As an application of the presented fuzzy strategies, we present a fuzzy-control based tennis simulator.

Ivancevic, Tijana T; Markovic, Sasa

2009-01-01T23:59:59.000Z

46

Human performance modeling for system of systems analytics.  

SciTech Connect (OSTI)

A Laboratory-Directed Research and Development project was initiated in 2005 to investigate Human Performance Modeling in a System of Systems analytic environment. SAND2006-6569 and SAND2006-7911 document interim results from this effort; this report documents the final results. The problem is difficult because of the number of humans involved in a System of Systems environment and the generally poorly defined nature of the tasks that each human must perform. A two-pronged strategy was followed: one prong was to develop human models using a probability-based method similar to that first developed for relatively well-understood probability based performance modeling; another prong was to investigate more state-of-art human cognition models. The probability-based modeling resulted in a comprehensive addition of human-modeling capability to the existing SoSAT computer program. The cognitive modeling resulted in an increased understanding of what is necessary to incorporate cognition-based models to a System of Systems analytic environment.

Dixon, Kevin R.; Lawton, Craig R.; Basilico, Justin Derrick; Longsine, Dennis E. (INTERA, Inc., Austin, TX); Forsythe, James Chris; Gauthier, John Henry; Le, Hai D.

2008-10-01T23:59:59.000Z

47

RESEARCH PAPER Modelling the Human Immune System by Combining  

E-Print Network [OSTI]

"virtual organism" simulation projects are currently underway in the US, Japan and Europe: Visible Human of immune system-related diseases where both timing and genomic information are of importance. Key wordsRESEARCH PAPER Modelling the Human Immune System by Combining Bioinformatics and Systems Biology

Utrecht, Universiteit

48

Marker-less Human Motion Estimation using Articulated Deformable Model  

E-Print Network [OSTI]

Marker-less Human Motion Estimation using Articulated Deformable Model Koichi Ogawara and Xiaolu Li and backtrack re-estimation algorithm enable accurate estimation. The power to track challenging whole body

Tokyo, University of

49

A multisensory observer model for human spatial orientation perception  

E-Print Network [OSTI]

Quantitative "observer" models for spatial orientation and eye movements have been developed based on 1-G data from humans and animals (e.g. Oman 1982, 1991, Merfeld, et al 1993, 2002; Haslwanter 2000, Vingerhoets 2006). ...

Newman, Michael C. (Michael Charles)

2009-01-01T23:59:59.000Z

50

Modeling aspects of human memory for scientific study.  

SciTech Connect (OSTI)

Working with leading experts in the field of cognitive neuroscience and computational intelligence, SNL has developed a computational architecture that represents neurocognitive mechanisms associated with how humans remember experiences in their past. The architecture represents how knowledge is organized and updated through information from individual experiences (episodes) via the cortical-hippocampal declarative memory system. We compared the simulated behavioral characteristics with those of humans measured under well established experimental standards, controlling for unmodeled aspects of human processing, such as perception. We used this knowledge to create robust simulations of & human memory behaviors that should help move the scientific community closer to understanding how humans remember information. These behaviors were experimentally validated against actual human subjects, which was published. An important outcome of the validation process will be the joining of specific experimental testing procedures from the field of neuroscience with computational representations from the field of cognitive modeling and simulation.

Caudell, Thomas P. (University of New Mexico); Watson, Patrick (University of Illinois - Champaign-Urbana Beckman Institute); McDaniel, Mark A. (Washington University); Eichenbaum, Howard B. (Boston University); Cohen, Neal J. (University of Illinois - Champaign-Urbana Beckman Institute); Vineyard, Craig Michael; Taylor, Shawn Ellis; Bernard, Michael Lewis; Morrow, James Dan; Verzi, Stephen J.

2009-10-01T23:59:59.000Z

51

The Multilayered Organization of Engineered Human Skin Does Not Influence the Formation of Sunlight-induced Cyclobutane Pyrimidine Dimers in Cellular DNA  

Science Journals Connector (OSTI)

...Laval University, Quebec, Canada G1K 7P4; Unite de Recherche en...Recherche, CHUQ, Quebec, Quebec, Canada G1L 3L5; and Faculty of Medicine...Maisonneuve-Rosemont, Montreal, Quebec, Canada H1T 2M4 E. A. D. Solar UVB initiates skin cancer mainly...

Jean-Philippe Therrien; Mahmoud Rouabhia; Elliot A. Drobetsky; and Régen Drouin

1999-01-15T23:59:59.000Z

52

A noninvasive skin imaging system Symon Cotton  

E-Print Network [OSTI]

A noninvasive skin imaging system Symon Cotton School of Computer Science, University Of Birmingham arriving at a diagnosis. A previous paper [Cotton and Claridge 1996] presented a model of colour formation­dimensional colour space, is limited to a curved surface [Cotton and Claridge 1996]. As abnormal skin often has a di

Claridge, Ela

53

Modeling and simulation of stable human locomotion using five degree-of-freedom gait model  

E-Print Network [OSTI]

Human locomotion involves a highly sophisticated and complex locomotive system. In order to understand how models of such system are built, it is useful to consider the meaning and implication of modeling and simulation as an attempt to represent...

Viswanathan, Vanisri

2012-06-07T23:59:59.000Z

54

Human Behavior and Energy Use: Modeling the Relationships  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Human Behavior and Energy Use: Modeling the Relationships Human Behavior and Energy Use: Modeling the Relationships Speaker(s): Bin Shui Thomas Sanquist Date: July 29, 2009 - 12:00pm Location: 90-3122 This presentation summarizes the conceptual framework and some initial data analyses for a Laboratory Directed Research and Development project to develop models of the relationships between human behavior, energy use, climate change and national/international security. A brief history of social science in energy research is provided, followed by methods and data from an approach involving Consumer Lifestyle Analysis. Growth patterns in energy usage in the residential and personal travel sectors are illustrated, along with the indirect energy requirements to support that usage. General research needs in the area of behavior are discussed, some

55

Human performance modeling for system of systems analytics :soldier fatigue.  

SciTech Connect (OSTI)

The military has identified Human Performance Modeling (HPM) as a significant requirement and challenge of future systems modeling and analysis initiatives as can be seen in the Department of Defense's (DoD) Defense Modeling and Simulation Office's (DMSO) Master Plan (DoD 5000.59-P 1995). To this goal, the military is currently spending millions of dollars on programs devoted to HPM in various military contexts. Examples include the Human Performance Modeling Integration (HPMI) program within the Air Force Research Laboratory, which focuses on integrating HPMs with constructive models of systems (e.g. cockpit simulations) and the Navy's Human Performance Center (HPC) established in September 2003. Nearly all of these initiatives focus on the interface between humans and a single system. This is insufficient in the era of highly complex network centric SoS. This report presents research and development in the area of HPM in a system-of-systems (SoS). Specifically, this report addresses modeling soldier fatigue and the potential impacts soldier fatigue can have on SoS performance.

Lawton, Craig R.; Campbell, James E.; Miller, Dwight Peter

2005-10-01T23:59:59.000Z

56

Science-Based Simulation Model of Human Performance for Human Reliability Analysis  

SciTech Connect (OSTI)

Human reliability analysis (HRA), a component of an integrated probabilistic risk assessment (PRA), is the means by which the human contribution to risk is assessed, both qualitatively and quantitatively. However, among the literally dozens of HRA methods that have been developed, most cannot fully model and quantify the types of errors that occurred at Three Mile Island. Furthermore, all of the methods lack a solid empirical basis, relying heavily on expert judgment or empirical results derived in non-reactor domains. Finally, all of the methods are essentially static, and are thus unable to capture the dynamics of an accident in progress. The objective of this work is to begin exploring a dynamic simulation approach to HRA, one whose models have a basis in psychological theories of human performance, and whose quantitative estimates have an empirical basis. This paper highlights a plan to formalize collaboration among the Idaho National Laboratory (INL), the University of Maryland, and The Ohio State University (OSU) to continue development of a simulation model initially formulated at the University of Maryland. Initial work will focus on enhancing the underlying human performance models with the most recent psychological research, and on planning follow-on studies to establish an empirical basis for the model, based on simulator experiments to be carried out at the INL and at the OSU.

Dana L. Kelly; Ronald L. Boring; Ali Mosleh; Carol Smidts

2011-10-01T23:59:59.000Z

57

Sensitivity analysis techniques for models of human behavior.  

SciTech Connect (OSTI)

Human and social modeling has emerged as an important research area at Sandia National Laboratories due to its potential to improve national defense-related decision-making in the presence of uncertainty. To learn about which sensitivity analysis techniques are most suitable for models of human behavior, different promising methods were applied to an example model, tested, and compared. The example model simulates cognitive, behavioral, and social processes and interactions, and involves substantial nonlinearity, uncertainty, and variability. Results showed that some sensitivity analysis methods create similar results, and can thus be considered redundant. However, other methods, such as global methods that consider interactions between inputs, can generate insight not gained from traditional methods.

Bier, Asmeret Brooke

2010-09-01T23:59:59.000Z

58

Double-Skin Façades  

Science Journals Connector (OSTI)

The double-skin façade is a system that consists of two building skins separated by a ventilated cavity (Fig. 9.1). The main aim of the cavity is to vary the physical properties of the façade throughout the ye...

2009-01-01T23:59:59.000Z

59

A Game Theory Based Model of Human Driving with Application to Autonomous and Mixed Driving  

E-Print Network [OSTI]

In this work, I consider the development of a driver model to better understand human drivers’ various behaviors in the upcoming mixed situation of human drivers and autonomous vehicles. For this, my current effort focuses on modeling the driver...

Yoo, Je Hong

2014-08-04T23:59:59.000Z

60

Adapting GOMS to Model Human-Robot Interaction  

SciTech Connect (OSTI)

Human-robot interaction (HRI) has been maturing in tandem with robots’ commercial success. In the last few years HRI researchers have been adopting—and sometimes adapting—human-computer interaction (HCI) evaluation techniques to assess the efficiency and intuitiveness of HRI designs. For example, Adams (2005) used Goal Directed Task Analysis to determine the interaction needs of officers from the Nashville Metro Police Bomb Squad. Scholtz et al. (2004) used Endsley’s (1988) Situation Awareness Global Assessment Technique to determine robotic vehicle supervisors’ awareness of when vehicles were in trouble and thus required closer monitoring or intervention. Yanco and Drury (2004) employed usability testing to determine (among other things) how well a search-andrescue interface supported use by first responders. One set of HCI tools that has so far seen little exploration in the HRI domain, however, is the class of modeling and evaluation techniques known as formal methods.

Drury, Jill; Scholtz, Jean; Kieras, David

2007-03-09T23:59:59.000Z

Note: This page contains sample records for the topic "human skin model" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


61

Sprayed skin turbine component  

DOE Patents [OSTI]

Fabricating a turbine component (50) by casting a core structure (30), forming an array of pits (24) in an outer surface (32) of the core structure, depositing a transient liquid phase (TLP) material (40) on the outer surface of the core structure, the TLP containing a melting-point depressant, depositing a skin (42) on the outer surface of the core structure over the TLP material, and heating the assembly, thus forming both a diffusion bond and a mechanical interlock between the skin and the core structure. The heating diffuses the melting-point depressant away from the interface. Subsurface cooling channels (35) may be formed by forming grooves (34) in the outer surface of the core structure, filling the grooves with a fugitive filler (36), depositing and bonding the skin (42), then removing the fugitive material.

Allen, David B

2013-06-04T23:59:59.000Z

62

Skin friction blistering: computer model.  

E-Print Network [OSTI]

on blisters produced by friction. I. Results of linearDuplantis KL, Jones BH. Friction blisters. Pathophysiology,WA, Sulzberger MB. The friction blister. Mil Med 6. Cortese

Xing, Malcolm; Pan, Ning; Zhong, Wen; Maibach, Howard

2007-01-01T23:59:59.000Z

63

Skin friction blistering: computer model.  

E-Print Network [OSTI]

K. L.Jones, B. H. , Friction blisters. Pathophysiology,and M.B. Sulzberger, The friction blister. Mil Med, 1972.on blisters produced by friction. II. The blister fluid. J

Xing, Malcolm; Pan, Ning; Zhong, Wen; Maibach, Howard

2007-01-01T23:59:59.000Z

64

Neutron removal cross section as a measure of neutron skin  

Science Journals Connector (OSTI)

We study the relation between neutron removal cross section (?-N) and neutron skin thickness for finite neutron-rich nuclei using the statistical abrasion ablation model. Different sizes of neutron skin are obtained by adjusting the diffuseness parameter of neutrons in the Fermi distribution. It is demonstrated that there is a good linear correlation between ?-N and the neutron skin thickness for neutron-rich nuclei. Further analysis suggests that the relative increase of neutron removal cross section could be used as a quantitative measure for neutron skin thickness in neutron-rich nuclei.

D. Q. Fang (???); Y. G. Ma (???); X. Z. Cai (???); W. D. Tian (???); H. W. Wang (???)

2010-04-07T23:59:59.000Z

65

Percutaneous penetration of uranium in rats after a contamination on intact or wounded skin  

Science Journals Connector (OSTI)

......hairless rats. Percutaneous penetration through wounded skin towards...1157-1165. Percutaneous penetration of uranium in rats after a...hairless rats. Percutaneous penetration through wounded skin towards...Kinetics Male Metabolic Clearance Rate Models, Biological Radiometry......

F. Petitot; C. Gautier; A. M. Moreels; S. Frelon; F. Paquet

2007-11-01T23:59:59.000Z

66

The Lysyl Oxidase LOX Is Absent in Basal and Squamous Cell Carcinomas and Its Knockdown Induces an Invading Phenotype in a Skin Equivalent Model  

Science Journals Connector (OSTI)

...a dermal substrate made of chitosan-cross-linked collagen-GAG...salt, Sigma), the classic inhibitor of the lysyl oxidase activity...that labels the nuclei. The chitosan-cross-linked collagen-GAG...6-Oxidase antagonists & inhibitors metabolism Skin Neoplasms...

Charbel Bouez; Caroline Reynaud; Emmanuelle Noblesse; Amélie Thépot; Claudine Gleyzal; Jean Kanitakis; Eric Perrier; Odile Damour; and Pascal Sommer

2006-03-01T23:59:59.000Z

67

Bayesian decision theory as a model of human visual perception: Testing Bayesian transfer  

E-Print Network [OSTI]

Bayesian decision theory as a model of human visual perception: Testing Bayesian transfer LAURENCE November 12, 2008) Abstract Bayesian decision theory (BDT) is a mathematical framework that allows without learning. Keywords: Perception, Bayesian decision theory, Statistical models, Loss function

Maloney, Laurence T.

68

Simulating the physiology of athletes during endurance sports events: modelling human energy conversion and metabolism  

Science Journals Connector (OSTI)

...somewhat slower to save energy for later). The motivational factors are represented by the...events: modelling human energy conversion and metabolism. | The...computational model for energy conversion during bicycle racing...

2011-01-01T23:59:59.000Z

69

A phenomenological muscle model to assess history dependent effects in human movement  

E-Print Network [OSTI]

A phenomenological muscle model to assess history dependent effects in human movement C.P. Mc of the history dependent effects. The phenomenological model of stretch-induced force enhancement was dependent

Ben-Yakar, Adela

70

Image-based modeling of human gaits with higher-order statistics Payam Saisan  

E-Print Network [OSTI]

, dynamic independent component analysis, human motion modeling, visual recognition, animation Abstract We in human motion can play a crucial role in a number of applications ranging from security (recognizing models for accuracy and predictive power. In particular, we exploit the higher- order statistical

Soatto, Stefano

71

A generalized 3D inverted pendulum model to represent human normal walking  

E-Print Network [OSTI]

A generalized 3D inverted pendulum model to represent human normal walking Sophie Sakka IRCCy,lacouture}@univ-poitiers.fr Abstract-- This paper compares different inverted pendulum models to represent the stance phase of human adapted to pathological walking as the walking symmetry hypothesis -needed to build classical inverted

Paris-Sud XI, Université de

72

Models of Human Expertise as Blueprints for Cognitive Engineering: Applications to Landmine Detection  

E-Print Network [OSTI]

of information-processing models of expertise for designing instruction and developing important human skills. 1Models of Human Expertise as Blueprints for Cognitive Engineering: Applications to Landmine projects described here took a cognitive engineering approach to improve detection capability via

Creswell, J. David

73

A critical review of methods and models for evaluating organizational factors in Human Reliability Analysis  

Science Journals Connector (OSTI)

Abstract This work makes a critical evaluation of the deficiencies concerning human factors and evaluates the potential of quantitative techniques that have been proposed in the last decades, like THERP (Technique for Human Error Rate Prediction), CREAM (Cognitive Reliability and Error Analysis Method), and ATHEANA (A Technique for Human Event Analysis), to model organizational factors, including cognitive processes in humans and interactions among humans and groups. Two important models are discussed in this context: STAMP (Systems-Theoretic Accident Model and Process), based on system theory and FRAM (Functional Resonance Analysis Method), which aims at modeling the nonlinearities of socio-technical systems. These models, however, are not yet being used in risk analysis similarly to Probabilistic Safety Analyses for safety assessment of nuclear reactors. However, STAMP has been successfully used for retrospective analysis of events, which would allow an extension of these studies to prospective safety analysis.

M.A.B. Alvarenga; P.F. Frutuoso e Melo; R.A. Fonseca

2014-01-01T23:59:59.000Z

74

Is a Swine Model of Arteriovenous Malformation Suitable for Human Extracranial Arteriovenous Malformation? A Preliminary Study  

SciTech Connect (OSTI)

Objective: A chronic arteriovenous malformation (AVM) model using the swine retia mirabilia (RMB) was developed and compared with the human extracranial AVM (EAVM) both in hemodynamics and pathology, to see if this brain AVM model can be used as an EAVM model. Methods: We created an arteriovenous fistula between the common carotid artery and the external jugular vein in eight animals by using end-to-end anastomosis. All animals were sacrificed 1 month after surgery, and the bilateral retia were obtained at autopsy and performed hematoxylin and eosin staining and immunohistochemistry. Pre- and postsurgical hemodynamic evaluations also were conducted. Then, the blood flow and histological changes of the animal model were compared with human EAVM. Results: The angiography after operation showed that the blood flow, like human EAVM, flowed from the feeding artery, via the nidus, drained to the draining vein. Microscopic examination showed dilated lumina and disrupted internal elastic lamina in both RMB of model and nidus of human EAVM, but the thickness of vessel wall had significant difference. Immunohistochemical reactivity for smooth muscle actin, angiopoietin 1, and angiopoietin 2 were similar in chronic model nidus microvessels and human EAVM, whereas vascular endothelial growth factor was significant difference between human EAVM and RMB of model. Conclusions: The AVM model described here is similar to human EAVM in hemodynamics and immunohistochemical features, but there are still some differences in anatomy and pathogenetic mechanism. Further study is needed to evaluate the applicability and efficacy of this model.

Lv, Ming-ming, E-mail: lvmingming001@163.com [Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Department of Oral and Maxillofacial Surgery, Shanghai Key Laboratory of Stomatology (China)] [Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Department of Oral and Maxillofacial Surgery, Shanghai Key Laboratory of Stomatology (China); Fan, Xin-dong, E-mail: fanxindong@yahoo.com.cn [Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Department of Radiology (China)] [Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Department of Radiology (China); Su, Li-xin, E-mail: sulixin1975@126.com [Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Department of Oral and Maxillofacial Surgery, Shanghai Key Laboratory of Stomatology (China)] [Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Department of Oral and Maxillofacial Surgery, Shanghai Key Laboratory of Stomatology (China)

2013-10-15T23:59:59.000Z

75

Human skin pigmentation, migration and disease susceptibility  

Science Journals Connector (OSTI)

...Dixon, K. M. , Sequeira, V. B., Camp, A. J., Mason, R. S. 2010 Vitamin...and pollution levels in 18th and 19th century Birmingham, England. Am. J. Phys...2007 Malignant melanoma in the 21st century. I. Epidemiology, risk factors, screening...

2012-01-01T23:59:59.000Z

76

Cerebral autoregulation and gas exchange studied using a human cardiopulmonary model  

E-Print Network [OSTI]

Cerebral autoregulation and gas exchange studied using a human cardiopulmonary model K. Lu,1 J. W autoregulation, brain gas ex- change, and their interaction by means of a mathematical model. We have previously of intracranial dynamics. However, their models did not include gas transport in brain tissue and thus can

77

Model of medical supply demand and astronaut health for long-duration human space flight  

E-Print Network [OSTI]

The medical care of space crews is the primary limiting factor in the achievement of long-duration space missions. (Nicogossian 2003) The goal of this thesis was to develop a model of long-duration human space flight ...

Assad, Albert

2009-01-01T23:59:59.000Z

78

Model of genetic variation in human social networks  

Science Journals Connector (OSTI)

...interesting causal pathways from genes to human network structure that merit exploration. For example, it was recently...Race and Sex. Behav Gen 28:265 ZZQQhy275. 3. Kendler KS, Nick G, Martin ACH, Eaves LJ (1995) ``Self-report psychiatric...

James H. Fowler; Christopher T. Dawes; Nicholas A. Christakis

2009-01-01T23:59:59.000Z

79

A reaction-diffusion model of the human brain development  

Science Journals Connector (OSTI)

The anatomical variability of the human brain folds remains an unclear and challenging issue. Several hypotheses coexist for explaining the rapid development of cortical sulci and it is clear that understanding their variability would improve the comparison ... Keywords: brain development, folding, reaction-diffusion equations

Julien Lefèvre; Jean-François Mangin

2010-04-01T23:59:59.000Z

80

A mid-layer model for human reliability analysis : understanding the cognitive causes of human failure events.  

SciTech Connect (OSTI)

The Office of Nuclear Regulatory Research (RES) at the US Nuclear Regulatory Commission (USNRC) is sponsoring work in response to a Staff Requirements Memorandum (SRM) directing an effort to establish a single human reliability analysis (HRA) method for the agency or guidance for the use of multiple methods. As part of this effort an attempt to develop a comprehensive HRA qualitative approach is being pursued. This paper presents a draft of the method's middle layer, a part of the qualitative analysis phase that links failure mechanisms to performance shaping factors. Starting with a Crew Response Tree (CRT) that has identified human failure events, analysts identify potential failure mechanisms using the mid-layer model. The mid-layer model presented in this paper traces the identification of the failure mechanisms using the Information-Diagnosis/Decision-Action (IDA) model and cognitive models from the psychological literature. Each failure mechanism is grouped according to a phase of IDA. Under each phase of IDA, the cognitive models help identify the relevant performance shaping factors for the failure mechanism. The use of IDA and cognitive models can be traced through fault trees, which provide a detailed complement to the CRT.

Shen, Song-Hua (US Nuclear Regulatory Commission, Washington, DC); Chang, James Y. H. (US Nuclear Regulatory Commission, Washington, DC); Boring,Ronald L. (Idaho National Laboratory, Idaho Falls, ID); Whaley, April M. (Idaho National Laboratory, Idaho Falls, ID); Lois, Erasmia (US Nuclear Regulatory Commission, Washington, DC); Hendrickson, Stacey M. Langfitt; Oxstrand, Johanna H. (Vattenfall Ringhals AB, Varobacka, Sweden); Forester, John Alan; Kelly, Dana L. (Idaho National Laboratory, Idaho Falls, ID); Mosleh, Ali (University of Maryland, College Park, MD)

2010-03-01T23:59:59.000Z

Note: This page contains sample records for the topic "human skin model" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


81

Evaluation of slug tests in wells containing a finite-thickness skin  

SciTech Connect (OSTI)

The effects of a finite-thickness skin (low-permeability zone surrounding the well bore face) on the response of slug tests is investigated by using a numerical model and a simple analytical solution. The results show that, for skins of finite thicknesses, estimates of hydraulic conductivity provided by slug tests can be more representative of the skin than of the surrounding formation. When a finite-thickness skin is present, the slug test response is shifted along the horizontal axis, making estimates of hydraulic conductivity unreliable. This result is different from that obtained by using an analytical solution for a skin of infinitesimal thickness.

Faust, C.R.; Mercer, J.W.

1984-04-01T23:59:59.000Z

82

Modeling Human Neural Development Using Pluripotent Stem Cells  

E-Print Network [OSTI]

Jaenisch R. Treatment of sickle cell anemia mouse model withharboring the mutation for sickle cell disease 20 . Despite

Patterson, Michaela Cyr

2012-01-01T23:59:59.000Z

83

Human-Assisted Virtual Environment Modeling for Robots  

Science Journals Connector (OSTI)

In order to avoid the complex calculation and poor robustness in automatic visual modeling process, a man-machine interaction based stereo vision system is developed for modeling an unknown environment. The operator‘s knowledge about a scene ... Keywords: man-machine interaction, modeling, virtual reality

J. G. Wang; Y. F. Li

1999-01-01T23:59:59.000Z

84

Modeling human location data with mixtures of kernel densities  

Science Journals Connector (OSTI)

Location-based data is increasingly prevalent with the rapid increase and adoption of mobile devices. In this paper we address the problem of learning spatial density models, focusing specifically on individual-level data. Modeling and predicting a spatial ... Keywords: anomaly/novelty detection, kernel density estimation, probabilistic methods, social media, spatial, user modeling

Moshe Lichman, Padhraic Smyth

2014-08-01T23:59:59.000Z

85

Modeling toxic endpoints for improving human health risk assessment  

E-Print Network [OSTI]

or equivalent toxicological potency in which case they are not considered ?sufficiently? similar. Currently, this method is only useful for inhalation 4 routes of exposure because epidemiological data for human oral and dermal exposures are not yet... available. Consequently, it is only feasible to use in cases where inhalation risk will be the dominant contributor to the overall risk estimates. This method is not considered a viable option for mixtures that have originated from unknown sources...

Bruce, Erica Dawn

2009-05-15T23:59:59.000Z

86

Saccular hearing; turtle model for a human prosthesis  

Science Journals Connector (OSTI)

The saccule is a hearingorgan is some vertebrates thought to be responsive to substrate vibration (bone conduction) or low?frequency aerial sound. There was likely some overlap in these functions in the course of evolution after the sensory area to become the cochlea migrated from the saccule. That overlap is preserved in extant turtles by columella (stapes) saccular coupling via fibroelastic strands; thus both organs can respond to air conduction and bone conduction stimulation. Evoked potential data however reflect differential AC/BC drive to the inner ear. The columellas inertia provides the force to displace the saccular wall with the tympanum providing damping. Intense AC stimulation likely stimulates the human saccule. A proprietary stapedial saccular strut is described that serves as a surgically implanted coupling device for humans allowing more efficient use of AC saccular hearing in clinical deafness. The human saccular resonance is about 350 Hz which should allow for sufficient speech coding for intelligibility assuming connectivity to the auditory neuraxis. BC stimulation through audible ultrasound also likely activates the saccule in individuals with profound deafness. A stand?alone stapedio?saccular strut or one used in combination with an ultrasonichearing aid offers the potential of communication through saccular hearing.

2006-01-01T23:59:59.000Z

87

Application of a canine {sup 238}Pu dosimetry model to human bioassay data  

SciTech Connect (OSTI)

Associated with the use of 2{sup 238}Pu in thermoelectric power sources for space probes and power supplies for cardiac devices is the potential for human exposure to {sup 238}Pu, primarily by inhalation. In the event of human internal exposure, a means is needed for assessing the level of intake and calculating radiation doses. Several bioassay/dosimetry models have been developed for {sup 239}Pu. However, results from studies with laboratory animals have indicated that the biokinetics, and therefore the descriptive models, of {sup 238}Pu are significantly different from those for {sup 239}Pu. A canine model accounting for these differences has been applied in this work to urinary excretion data from seven humans occupationally exposed to low levels of an insoluble {sup 238}Pu compound. The modified model provides a good description of the urinary excretion kinetics observed in the exposed humans. The modified model was also used to provide estimates of the initial intakes of {sup 238}Pu for the seven individuals; these estimates ranged from 4.5 nCi (170 Bq) to 87 nCi (3200 Bq). Autopsy data on the amount and distribution of {sup 238}Pu retained in the organs may be used in the future to validate or refute both these estimates and the assumptions used to formulate the human model. Modification of the human model to simulate an injection exposure to {sup 239}Pu gave patterns of retention in the organs and urinary excretion comparable to those seen previously in humans; further modification of the model using fecal data (unavailable for the subjects of this study) is indicated.

Hickman, A.W. Jr. [Florida Univ., Gainesville, FL (United States)

1991-08-01T23:59:59.000Z

88

32 July/August2010 PublishedbytheIEEEComputerSociety 0272-1716/10/$26.002010IEEE DigitalHumanFaces  

E-Print Network [OSTI]

- able in skin than in, say, a wax candle. Correctly depicting human skin is important in fields that it integrates well with existing pipelines. Several real-time algorithms for simulating skin exist (for more

Gutierrez, Diego

89

ARM - Measurement - Surface skin temperature  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

skin temperature skin temperature ARM Data Discovery Browse Data Comments? We would love to hear from you! Send us a note below or call us at 1-888-ARM-DATA. Send Measurement : Surface skin temperature The radiative surface skin temperature, from an IR thermometer measuring the narrowband radiating temperature of the ground surface in its field of view. Categories Radiometric, Surface Properties Instruments The above measurement is considered scientifically relevant for the following instruments. Refer to the datastream (netcdf) file headers of each instrument for a list of all available measurements, including those recorded for diagnostic or quality assurance purposes. ARM Instruments IRT : Infrared Thermometer MFRIRT : Multifilter Radiometer and Infrared Thermometer External Instruments

90

Emerging Nanomedicine for Skin Cancer  

Science Journals Connector (OSTI)

Skin cancer is a common cancer and is associated with significant morbidity and mortality. Topical treatment is an attractive option compared with systemic route due to the reduced association with systemic to...

Puiyan Lee; Adnan Nasir; Kenneth K. Y. Wong

2013-01-01T23:59:59.000Z

91

Sensitive skins and somatic processing for affective and sociable robots based upon a somatic alphabet approach  

E-Print Network [OSTI]

The sense of touch is one of the most important senses of the human body. This thesis describes the biologically inspired design of "sensitive skins" for two different robotic platforms: Leonardo, a high degree-of-freedom, ...

Stiehl, Walter Daniel, 1980-

2005-01-01T23:59:59.000Z

92

Detecting pornographic images by localizing skin Sotiris Karavarsamisa  

E-Print Network [OSTI]

specialized sub- classes, namely "bikini" / "porn" and "skin" / "non-skin", respectively. The extracted

Blekas, Konstantinos

93

Nonintrusive 3D reconstruction of human bone models to simulate their bio-mechanical response  

Science Journals Connector (OSTI)

3D finite element models representing functional parts of the human skeletal system, have been repeatedly introduced over the last years, to simulate biomechanical response of anatomical characteristics or investigate surgical treatment. The reconstruction ... Keywords: 3D imaging, Bio-mechanical response, Computed tomography, FEM modeling

Tsouknidas Alexander; Lontos Antonis; Savvakis Savvas; Michailidis Nikolaos

2012-06-01T23:59:59.000Z

94

Graphs of models for exploring design spaces in the engineering of Human Computer Interaction  

E-Print Network [OSTI]

Graphs of models for exploring design spaces in the engineering of Human Computer Interaction +33 (0)4 76 51 48 54 gaelle.calvary@imag.fr ABSTRACT Model Driven Engineering (MDE) has focused creativity in the early phases. Our research aims at stretching MDE all over the design process including

Paris-Sud XI, Université de

95

A naturalistic decision making model for simulated human combatants  

SciTech Connect (OSTI)

The authors describe a naturalistic behavioral model for the simulation of small unit combat. This model, Klein's recognition-primed decision making (RPD) model, is driven by situational awareness rather than a rational process of selecting from a set of action options. They argue that simulated combatants modeled with RPD will have more flexible and realistic responses to a broad range of small-scale combat scenarios. Furthermore, they note that the predictability of a simulation using an RPD framework can be easily controlled to provide multiple evaluations of a given combat scenario. Finally, they discuss computational issues for building an RPD-based behavior engine for fully automated combatants in small conflict scenarios, which are being investigated within Sandia's Next Generation Site Security project.

HUNTER,KEITH O.; HART,WILLIAM E.; FORSYTHE,JAMES C.

2000-05-01T23:59:59.000Z

96

Statistical evaluation of alternative models of human evolution  

Science Journals Connector (OSTI)

...origin with assimilation (see SI Fig. 7B ) is a “hybrid” model that includes an early dispersal of H. erectus...European project for providing access to its computing grid infrastructure and for user assistance. We thank Pierre Berthier...

Nelson J. R. Fagundes; Nicolas Ray; Mark Beaumont; Samuel Neuenschwander; Francisco M. Salzano; Sandro L. Bonatto; Laurent Excoffier

2007-01-01T23:59:59.000Z

97

Physical model of human blood electronic memristors network  

Science Journals Connector (OSTI)

For the first time using therapeutic methodology, network of physical model (three memristors in series and parallel combination) of memristors was experimentally studied. The combination of memristors manifested memristor's characteristics (only as defined by Williams of HP, USA). Key potential applications towards biomedical electronics specially man-machine interface, artificial brain, and signal processing is envisaged.

Shiv Prasad Kosta; Mukta Bhatele; Prateek Gupta; Preeti Nair; Shakti Kosta; Siddharth Dutt Choubey; Luni Thakre; Piyush R. Vaghela; K.N. Patel; B.K. Dave; Jaimin Chavda; Chintan Bhatt; Tushar Nigam

2014-01-01T23:59:59.000Z

98

Estimation of expected human attention weights based on a decision field theory model  

Science Journals Connector (OSTI)

Abstract Modeling human decision making behavior is of great interest in understanding how a decision maker weights different decision attributes when making a decision. Such knowledge is critically important in helping predict future decisions, evaluating human decision performance, and improving the design of human and machine interface systems. Decision field theory (DFT) provides a psychological representation of the cognitive deliberation process, which is driven by the fluctuations of a person’s attention among decision attributes. In this research area, the most common use of a DFT model is to estimate or predict the human decisions by using a set of pre-specified expected attention weights (EAWs) in the DFT model. Unlike other research, this paper extends the capabilities of DFT in a complementary direction, showing how to fit or train a DFT model by estimating the EAW based on sequentially obtained samples of decision trials. Furthermore, the inherent connection between the EAW and the decision choice uncertainty is investigated. The proposed modeling method is discussed in detail for a two-alternative decision scenario based on two attributes. Both simulations and a case study are conducted in the paper to demonstrate the effectiveness of the proposed modeling approach.

Andres G. Abad; Jionghua (Judy) Jin; Young-Jun Son

2014-01-01T23:59:59.000Z

99

Neutron skins and neutron stars  

Science Journals Connector (OSTI)

Background: The neutron skin of a heavy nucleus as well as many neutron-star properties are highly sensitive to the poorly constrained density dependence of the symmetry energy.Purpose: To provide for the first time meaningful theoretical errors and to assess the degree of correlation between the neutron-skin thickness of 208Pb and several neutron-star properties.Methods: A proper covariance analysis based on the predictions of an accurately calibrated relativistic functional “FSUGold” is used to quantify theoretical errors and correlation coefficients.Results: We find correlation coefficients of nearly 1 (or ?1) between the neutron-skin thickness of 208Pb and a host of observables of relevance to the structure, dynamics, and composition of neutron stars.Conclusions: We suggest that a follow-up Lead Radius Experiment (PREX) measurement, ideally with a 0.5% accuracy, could significantly constrain the equation of state of neutron-star matter.

F. J. Fattoyev and J. Piekarewicz

2012-07-05T23:59:59.000Z

100

Human-robot cross-training: Computational formulation, modeling and evaluation of a human team training strategy  

E-Print Network [OSTI]

We design and evaluate human-robot cross-training, a strategy widely used and validated for effective human team training. Cross-training is an interactive planning method in which a human and a robot iteratively switch ...

Nikolaidis, Stefanos

Note: This page contains sample records for the topic "human skin model" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


101

Integrating digital human modeling into virtual environment for ergonomic oriented design  

E-Print Network [OSTI]

Virtual human simulation integrated into virtual reality applications is mainly used for virtual representation of the user in virtual environment or for interactions between the user and the virtual avatar for cognitive tasks. In this paper, in order to prevent musculoskeletal disorders, the integration of virtual human simulation and VR application is presented to facilitate physical ergonomic evaluation, especially for physical fatigue evaluation of a given population. Immersive working environments are created to avoid expensive physical mock-up in conventional evaluation methods. Peripheral motion capture systems are used to capture natural movements and then to simulate the physical operations in virtual human simulation. Physical aspects of human's movement are then analyzed to determine the effort level of each key joint using inverse kinematics. The physical fatigue level of each joint is further analyzed by integrating a fatigue and recovery model on the basis of physical task parameters. All the pr...

Ma, Liang; Bennis, Fouad; Hu, Bo; Zhang, Wei

2010-01-01T23:59:59.000Z

102

"Skin Cancer-What to Look For" Rochester Recreation  

E-Print Network [OSTI]

"Skin Cancer- What to Look For" Rochester Recreation Club for the Deaf May 20, 2010 #12;Supporters for the Deaf ("REAP") #12;Overview Skin Overview What is skin cancer? Who is at risk? How common is skin cancer? Signs of skin cancer Prevention Treatments #12;Skin Overview Skin is the largest organ in your body

Goldman, Steven A.

103

MODELLING THE HUMAN INDUCED VIBRATIONS IN ACABLE-STAYED PEDESTRIAN TIMBER BRIDGE  

E-Print Network [OSTI]

MODELLING THE HUMAN INDUCED VIBRATIONS IN ACABLE-STAYED PEDESTRIAN TIMBER BRIDGE Sara Casciati1 on a pedestrian timber bridge under different "moving" loads configurations are reported and analysed by applying behavior of the bridge under the above loads. A first in situ experimental campaign was carried out

Boyer, Edmond

104

Human Leg Model Predicts Ankle Muscle-Tendon Morphology, State, Roles and Energetics in Walking  

E-Print Network [OSTI]

Human Leg Model Predicts Ankle Muscle-Tendon Morphology, State, Roles and Energetics in Walking to be established. Here we develop a computational framework to address how the ankle joint actuation problem-tendon morphology and neural activations enable a metabolically optimal realization of biological ankle mechanics

Herr, Hugh

105

Regional Characterization of Freshwater Use in LCA: Modeling Direct Impacts on Human Health  

Science Journals Connector (OSTI)

Regional Characterization of Freshwater Use in LCA: Modeling Direct Impacts on Human Health ... Life cycle assessment (LCA) is a methodology that quantifies potential environmental impacts for comparative purposes in a decision-making context. ... While potential environmental impacts from pollutant emissions into water are characterized in LCA, impacts from water unavailability are not yet fully quantified. ...

Anne-Marie Boulay; Cécile Bulle; Jean-Baptiste Bayart; Louise Deschênes; Manuele Margni

2011-09-09T23:59:59.000Z

106

Evaluation of navy shipboard habitability for a warship design using human model  

Science Journals Connector (OSTI)

Recently, ergonomic design is a key issue in the warship design. Ergonomic ship design aims to improve the safety and convenience of crew and passengers. In this paper, as a basis of analyzing and evaluating ergonomic design criteria and evaluation methods ... Keywords: human model, shipboard habitability, warship design

Hongtae Kim; Jin H. Park; Hojin Hwang; Chang-Min Lee

2007-07-01T23:59:59.000Z

107

Flux analysis of the human proximal colon using anaerobic digestion model 1  

Science Journals Connector (OSTI)

Abstract The colon can be regarded as an anaerobic digestive compartment within the gastro intestinal tract (GIT). An in silico model simulating the fluxes in the human proximal colon was developed on basis of the anaerobic digestion model 1 (ADM1), which is traditionally used to model waste conversion to biogas. Model calibration was conducted using data from in vitro fermentation of the proximal colon (TIM-2), and, amongst others, supplemented with the bio kinetics of prebiotic galactooligosaccharides (GOS) fermentation. The impact of water and solutes absorption by the host was also included. Hydrolysis constants of carbohydrates and proteins were estimated based on total short chain fatty acids (SCFA) and ammonia production in vitro. Model validation was established using an independent dataset of a different in vitro model: an in vitro three-stage continuous culture system. The in silico model was shown to provide quantitative insight in the microbial community structure in terms of functional groups, and the substrate and product fluxes between these groups as well as the host, as a function of the substrate composition, pH and the solids residence time (SRT). The model confirms the experimental observation that methanogens are washed out at low pH or low SRT-values. The in silico model is proposed as useful tool in the design of experimental setups for in vitro experiments by giving insight in fermentation processes in the proximal human colon.

Anne Marieke Motelica-Wagenaar; Arjen Nauta; Ellen G.H.M. van den Heuvel; Robbert Kleerebezem

2014-01-01T23:59:59.000Z

108

Help:Skins | Open Energy Information  

Open Energy Info (EERE)

Skins Skins Jump to: navigation, search Clicking on the my preferences link in the upper right while logged in then click on the Skin button to change your skin. You can also preview the skin by clicking the (preview) links next to each skin. You can make changes to the current skin's stylesheet file (CSS) by creating a subpage of your userpage, "User:Yourname/monobook.css" for example. This requires your site admin to have enabled this feature -- if it is, you will see advice text at the top of your custom CSS page about clearing your browser's cache. Tools.png Tip for wiki admins: To enable this feature, you have to set $wgAllowUserCss to your LocalSettings.php. See also Help:Preferences Manual:Gallery of user styles (no official skins) Retrieved from

109

Turbine vane with high temperature capable skins  

DOE Patents [OSTI]

A turbine vane assembly includes an airfoil extending between an inner shroud and an outer shroud. The airfoil can include a substructure having an outer peripheral surface. At least a portion of the outer peripheral surface is covered by an external skin. The external skin can be made of a high temperature capable material, such as oxide dispersion strengthened alloys, intermetallic alloys, ceramic matrix composites or refractory alloys. The external skin can be formed, and the airfoil can be subsequently bi-cast around or onto the skin. The skin and the substructure can be attached by a plurality of attachment members extending between the skin and the substructure. The skin can be spaced from the outer peripheral surface of the substructure such that a cavity is formed therebetween. Coolant can be supplied to the cavity. Skins can also be applied to the gas path faces of the inner and outer shrouds.

Morrison, Jay A. (Oviedo, FL)

2012-07-10T23:59:59.000Z

110

Public expenditures on education, human capital and growth in Canada: An OLG model analysis  

Science Journals Connector (OSTI)

Much of the current debate in ageing countries focuses on whether governments should increase investments in human capital. We address this issue by simulating the effects of additional education spending using an overlapping-generations model applied to Canada. In the context of population ageing, the results indicate that how the policy is funded has powerful impacts on the targeted outcomes. Higher education incentives may increase the rate of human capital accumulation and mitigate the negative effects of slowing labour force growth. However, the impact depends on the distortions implied by alternative tax instruments and the efficiency of public expenditures on education.

Nabil Annabi; Simon Harvey; Yu Lan

2011-01-01T23:59:59.000Z

111

Thermal simulation of buildings with double-skin façades  

Science Journals Connector (OSTI)

Highly glazed commercial buildings with double-skin façades may overheat during summertime due to a coincidence of high outside temperatures, solar gains and internal heat gains. To optimize thermal comfort and minimize cooling loads, the thermal behaviour of this type of building, therefore, requires careful investigation at the design stage. However, complex physical phenomena—notably optical, thermodynamic and fluid dynamic processes—are involved and as yet, no single simulation tool is able to handle all these processes while remaining an efficient design tool. This paper presents a method based on the coupling of three different types of simulation models that is economical in terms of computing time, and thereby, suitable for design purposes. These models are: spectral optical model, computational fluid dynamics model and building energy simulation model. Various tools are available at each modelling level. The method is demonstrated on a commercial building with double-skin façades and additionally, night-time ventilation.

H. Manz; Th. Frank

2005-01-01T23:59:59.000Z

112

Skin Sensitivity and the Cold  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Skin Sensitivity and the Cold Skin Sensitivity and the Cold Name: Richard Location: N/A Country: N/A Date: N/A Question: A student in my anatomy and physiology class asked me, "When it's very cold outside in the winter, why does your skin hurt MORE than usual when you bang your finger or someone slaps you on the arm?" Replies: Wow! This is one outstanding question. Mammals respond to cold weather with the hypothalamus releasing thyrotropin releasing factor. This production increases with the severity of the cold weather and the length of the exposure to cold over a long period of time (at least three to four weeks). The thyroid responds by slowly increasing in size and releases thyroxine at higher quantities. Thyroxine increases the sensitivity of the entire nervous system. As a matter of fact, as you probably know, it increases the metabolism wholesale! within the body. This gets complicated so I'm keeping it simple. So, the bottom line is thyroxine. It just heightens our sensitivity not only to cold but our entire nervous system is enhanced.

113

A new muscle fatigue and recovery model and its ergonomics application in human simulation  

E-Print Network [OSTI]

Although automatic techniques have been employed in manufacturing industries to increase productivity and efficiency, there are still lots of manual handling jobs, especially for assembly and maintenance jobs. In these jobs, musculoskeletal disorders (MSDs) are one of the major health problems due to overload and cumulative physical fatigue. With combination of conventional posture analysis techniques, digital human modelling and simulation (DHM) techniques have been developed and commercialized to evaluate the potential physical exposures. However, those ergonomics analysis tools are mainly based on posture analysis techniques, and until now there is still no fatigue index available in the commercial software to evaluate the physical fatigue easily and quickly. In this paper, a new muscle fatigue and recovery model is proposed and extended to evaluate joint fatigue level in manual handling jobs. A special application case is described and analyzed by digital human simulation technique.

Ma, Liang; Bennis, Fouad; Zhang, Wei; Guillaume, François; 10.1080/17452759.2010.504056

2010-01-01T23:59:59.000Z

114

A new muscle fatigue and recovery model and its ergonomics application in human simulation  

E-Print Network [OSTI]

Although automatic techniques have been employed in manufacturing industries to increase productivity and efficiency, there are still lots of manual handling jobs, especially for assembly and maintenance jobs. In these jobs, musculoskeletal disorders (MSDs) are one of the major health problems due to overload and cumulative physical fatigue. With combination of conventional posture analysis techniques, digital human modelling and simulation (DHM) techniques have been developed and commercialized to evaluate the potential physical exposures. However, those ergonomics analysis tools are mainly based on posture analysis techniques, and until now there is still no fatigue index available in the commercial software to evaluate the physical fatigue easily and quickly. In this paper, a new muscle fatigue and recovery model is proposed and extended to evaluate joint fatigue level in manual handling jobs. A special application case is described and analyzed by digital human simulation technique.

Ma, Liang; Bennis, Fouad; Zhang, Wei; Guillaume, François

2009-01-01T23:59:59.000Z

115

Modeling and Simulation for Exploring Human-Robot Team Interaction Requirements  

SciTech Connect (OSTI)

Small-sized and micro-robots will soon be available for deployment in large-scale forces. Consequently, the ability of a human operator to coordinate and interact with largescale robotic forces is of great interest. This paper describes the ways in which modeling and simulation have been used to explore new possibilities for human-robot interaction. The paper also discusses how these explorations have fed implementation of a unified set of command and control concepts for robotic force deployment. Modeling and simulation can play a major role in fielding robot teams in actual missions. While live testing is preferred, limitations in terms of technology, cost, and time often prohibit extensive experimentation with physical multi-robot systems. Simulation provides insight, focuses efforts, eliminates large areas of the possible solution space, and increases the quality of actual testing.

Dudenhoeffer, Donald Dean; Bruemmer, David Jonathon; Davis, Midge Lee

2001-12-01T23:59:59.000Z

116

Interpretation of the modality of touch on an artificial arm covered with an EIT-based sensitive skin  

Science Journals Connector (OSTI)

During social interaction humans extract important information from tactile stimuli that can improve their understanding of the interaction. The development of a similar capability in a robot will contribute to the future success of intuitive human-robot ... Keywords: LogitBoost, Physical human-robot interaction, artificial sensitive skin, electrical impedance tomography, force and tactile sensing, recognition, sensing and perception, supervised machine learning

David Silvera Tawil; David Rye; Mari Velonaki

2012-11-01T23:59:59.000Z

117

Aspartic proteases from Plasmodium chabaudi: a rodent model for human malaria  

Science Journals Connector (OSTI)

Intraerythrocytic malaria parasites degrade haemoglobin to provide nutrients for their own growth and maturation. Plasmodium aspartic proteases known as plasmepsins play an important role on haemoglobin degradation and are being studied as drug targets for chemotherapy of malaria. The rodent model for human malaria, Plasmodium chabaudi, is an experimentally good model for therapy drug design. The gene encoding an aspartic protease precursor (proplasmepsin) from the rodent malaria parasite P. chabaudi was cloned and sequenced. A theoretical 3D structure model was constructed by comparative homology and used for superimposition with other known models. Analysis of the P. chabaudi and Plasmodium yoelli genomes revealed in both the presence of at least seven plasmepsins and each one has sequence similarity to its plasmepsin counterpart of the human malaria Plasmodium falciparum. The predicted proteins were confirmed as plasmepsins by detection on Blocks Database of three characteristic blocks of the eukaryotic and viral aspartic protease family. Analysis of the proline-rich loop amino acid sequence of these plasmepsins suggests that they constitute characteristic motifs of each plasmepsin group suggesting that these sequence variations are related with different substrate specificities.

Tiago M Martins; Carlos Novo; Virg??lio E do Rosário; Ana Domingos

2003-01-01T23:59:59.000Z

118

A Nonhuman Primate Model of Human Radiation-Induced Venocclusive Liver Disease and Hepatocyte Injury  

SciTech Connect (OSTI)

Background: Human liver has an unusual sensitivity to radiation that limits its use in cancer therapy or in preconditioning for hepatocyte transplantation. Because the characteristic veno-occlusive lesions of radiation-induced liver disease do not occur in rodents, there has been no experimental model to investigate the limits of safe radiation therapy or explore the pathogenesis of hepatic veno-occlusive disease. Methods and Materials: We performed a dose-escalation study in a primate, the cynomolgus monkey, using hypofractionated stereotactic body radiotherapy in 13 animals. Results: At doses ?40 Gy, animals developed a systemic syndrome resembling human radiation-induced liver disease, consisting of decreased albumin, elevated alkaline phosphatase, loss of appetite, ascites, and normal bilirubin. Higher radiation doses were lethal, causing severe disease that required euthanasia approximately 10 weeks after radiation. Even at lower doses in which radiation-induced liver disease was mild or nonexistent, latent and significant injury to hepatocytes was demonstrated by asialoglycoprotein-mediated functional imaging. These monkeys developed hepatic failure with encephalopathy when they received parenteral nutrition containing high concentrations of glucose. Histologically, livers showed central obstruction via an unusual intimal swelling that progressed to central fibrosis. Conclusions: The cynomolgus monkey, as the first animal model of human veno-occlusive radiation-induced liver disease, provides a resource for characterizing the early changes and pathogenesis of venocclusion, for establishing nonlethal therapeutic dosages, and for examining experimental therapies to minimize radiation injury.

Yannam, Govardhana Rao [Department of Surgery, University of Nebraska Medical Center, Omaha, Nebraska (United States); Han, Bing [Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania (United States); Department of Hepatobiliary Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi (China); Setoyama, Kentaro [Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania (United States); Yamamoto, Toshiyuki [Department of Surgery, University of Nebraska Medical Center, Omaha, Nebraska (United States); Ito, Ryotaro; Brooks, Jenna M. [Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania (United States); Guzman-Lepe, Jorge [Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania (United States); Department of Pathology, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania (United States); Galambos, Csaba [Department of Pathology, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania (United States); Fong, Jason V. [Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania (United States); Deutsch, Melvin; Quader, Mubina A. [Department of Radiation Oncology, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania (United States); Yamanouchi, Kosho [Department of Radiation Oncology, Albert Einstein College of Medicine, Bronx, New York (United States); Marion Bessin Liver Research Center, Albert Einstein College of Medicine, Bronx, New York (United States); Kabarriti, Rafi; Mehta, Keyur [Department of Radiation Oncology, Albert Einstein College of Medicine, Bronx, New York (United States); Soto-Gutierrez, Alejandro [Department of Pathology, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania (United States); McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania (United States); and others

2014-02-01T23:59:59.000Z

119

Pharmacokinetic modeling: Prediction and evaluation of route dependent dosimetry of bisphenol A in monkeys with extrapolation to humans  

SciTech Connect (OSTI)

A physiologically based pharmacokinetic (PBPK) model was developed for bisphenol A (BPA) in adult rhesus monkeys using intravenous (iv) and oral bolus doses of 100 {mu}g d6-BPA/kg (). This calibrated PBPK adult monkey model for BPA was then evaluated against published monkey kinetic studies with BPA. Using two versions of the adult monkey model based on monkey BPA kinetic data from and , the aglycone BPA pharmacokinetics were simulated for human oral ingestion of 5 mg d16-BPA per person (Voelkel et al., 2002). Voelkel et al. were unable to detect the aglycone BPA in plasma, but were able to detect BPA metabolites. These human model predictions of the aglycone BPA in plasma were then compared to previously published PBPK model predictions obtained by simulating the Voelkel et al. kinetic study. Our BPA human model, using two parameter sets reflecting two adult monkey studies, both predicted lower aglycone levels in human serum than the previous human BPA PBPK model predictions. BPA was metabolized at all ages of monkey (PND 5 to adult) by the gut wall and liver. However, the hepatic metabolism of BPA and systemic clearance of its phase II metabolites appear to be slower in younger monkeys than adults. The use of the current non-human primate BPA model parameters provides more confidence in predicting the aglycone BPA in serum levels in humans after oral ingestion of BPA. -- Highlights: Black-Right-Pointing-Pointer A bisphenol A (BPA) PBPK model for the infant and adult monkey was constructed. Black-Right-Pointing-Pointer The hepatic metabolic rate of BPA increased with age of the monkey. Black-Right-Pointing-Pointer The systemic clearance rate of metabolites increased with age of the monkey. Black-Right-Pointing-Pointer Gut wall metabolism of orally administered BPA was substantial across all ages of monkeys. Black-Right-Pointing-Pointer Aglycone BPA plasma concentrations were predicted in humans orally given oral doses of deuterated BPA.

Fisher, Jeffrey W., E-mail: jeffrey.fisher@fda.hhs.gov; Twaddle, Nathan C.; Vanlandingham, Michelle; Doerge, Daniel R.

2011-11-15T23:59:59.000Z

120

Development and Construction of Bioclimatic Double Skin Active Facade for Hot and Humid Climate of UAE  

E-Print Network [OSTI]

tracking venetian blinds, LED (light emitting diodes) lighting and Building Management system. 1.01 Modeling And Simulation Of Double Skin Active Facade The modeling and simulation of the Double Skin Fa?ade Cavity is a complicated task, since... sweating/condensation on the water coil. 3.06 LED (Light Emitting Diode) Lighting The building is illuminated using extremely energy efficient LED?s which last 5 times as long as fluorescents and 50 times longer than typical incandescent. So...

Karbor, R. G.; Mohamed, I.

2010-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "human skin model" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


121

A mathematical model of probability of conception in humans, and an analysis of the rhythm technique of birth control  

E-Print Network [OSTI]

A MATHEMATICAL MODEL OF PROBABILITY OF CONCEPTION IN HUMANS, AND AN ANALYSIS OF THE RHYTHM TECHNIQUE OF BIRTH CONTROL A Thesis by ALAN WALTER NORDHEIM Submitted to the 'Graduate College of Texas A&M University in partial fulfillment... of the requirement for the degree of MASTER OF SCIENCE August 1979 Major Subject: Bioengineering A MATHEMATICAL MODEL OF PROBABILITY OF CONCEPTION IN HUMANS, AND AN ANALYSIS OF THE RHYTHM TECHNIQUE OF BIRTH CONTROL A Thesis by ALAN WALTER NORDHEIM Approved...

Nordheim, Alan Walter

1979-01-01T23:59:59.000Z

122

Modeling and Quantification of Team Performance in Human Reliability Analysis for Probabilistic Risk Assessment  

SciTech Connect (OSTI)

Probabilistic Risk Assessment (PRA) and Human Reliability Assessment (HRA) are important technical contributors to the United States (U.S.) Nuclear Regulatory Commission’s (NRC) risk-informed and performance based approach to regulating U.S. commercial nuclear activities. Furthermore, all currently operating commercial NPPs in the U.S. are required by federal regulation to be staffed with crews of operators. Yet, aspects of team performance are underspecified in most HRA methods that are widely used in the nuclear industry. There are a variety of "emergent" team cognition and teamwork errors (e.g., communication errors) that are 1) distinct from individual human errors, and 2) important to understand from a PRA perspective. The lack of robust models or quantification of team performance is an issue that affects the accuracy and validity of HRA methods and models, leading to significant uncertainty in estimating HEPs. This paper describes research that has the objective to model and quantify team dynamics and teamwork within NPP control room crews for risk informed applications, thereby improving the technical basis of HRA, which improves the risk-informed approach the NRC uses to regulate the U.S. commercial nuclear industry.

Jeffrey C. JOe; Ronald L. Boring

2014-06-01T23:59:59.000Z

123

Evaluation of AirGIS: a GIS-based air pollution and human exposure modelling system  

Science Journals Connector (OSTI)

This study describes in brief the latest extensions of the Danish Geographic Information System (GIS)-based air pollution and human exposure modelling system (AirGIS), which has been developed in Denmark since 2001 and gives results of an evaluation with measured air pollution data. The system shows, in general, a good performance for both long-term averages (annual and monthly averages), short-term averages (hourly and daily) as well as when reproducing spatial variation in air pollution concentrations. Some shortcomings and future perspectives of the system are discussed too.

Matthias Ketzel; Ruwim Berkowicz; Martin Hvidberg; Steen Solvang Jensen; Ole Raaschou-Nielsen

2011-01-01T23:59:59.000Z

124

Neutron skin of $^{208}$Pb from Coherent Pion Photoproduction  

E-Print Network [OSTI]

Information on the size and shape of the neutron skin on $^{208}$Pb has been extracted from coherent pion photoproduction cross sections measured using the Crystal Ball together with the Glasgow tagger at the MAMI electron beam facility. On exploitation of an interpolated fit of a theoretical model to the measured cross sections the half-height radius and diffuseness of the neutron distribution are found to be 6.70$\\pm 0.03(stat)$ fm and 0.55$\\pm 0.01(stat)$$^{+0.02}_{-0.03}(sys)$ fm respectively, corresponding to a neutron skin thickness $\\Delta r_{np}$=0.15$\\pm 0.03(stat)$$^{+0.01}_{-0.03}(sys)$ fm. The results give the first successful extraction of a neutron skin with an electromagnetic probe and indicate the skin of $^{208}$Pb has a halo character. The measurement provides valuable new constraints on both the structure of nuclei and the equation of state for neutron-rich matter.

C. M. Tarbert; D. P. Watts; D. I. Glazier; P. Aguar; J. Ahrens; J. R. M. Annand; H. J. Arends; R. Beck; V. Bekrenev; B. Boillat; A. Braghieri; D. Branford; W. J. Briscoe; J. Brudvik; S. Cherepnya; R. Codling; E. J. Downie; K. Foehl; P. Grabmayr; R. Gregor; E. Heid; D. Hornidge; O. Jahn; V. L. Kashevarov; A. Knezevic; R. Kondratiev; M. Korolija; M. Kotulla; D. Krambrich; B. Krusche; M. Lang; V. Lisin; K. Livingston; S. Lugert; I. J. D. MacGregor; D. M. Manley; M. Martinez; J. C. McGeorge; D. Mekterovic; V. Metag; B. M. K. Nefkens; A. Nikolaev; R. Novotny; R. O. Owens; P. Pedroni; A. Polonski; S. N. Prakhov; J. W. Price; G. Rosner; M. Rost; T. Rostomyan; S. Schadmand; S. Schumann; D. Sober; A. Starostin; I. Supek; A. Thomas; M. Unverzagt; Th. Walcher; F. Zehr

2013-11-01T23:59:59.000Z

125

Bio-inspired nanocomposite assemblies as smart skin components.  

SciTech Connect (OSTI)

There is national interest in the development of sophisticated materials that can automatically detect and respond to chemical and biological threats without the need for human intervention. In living systems, cell membranes perform such functions on a routine basis, detecting threats, communicating with the cell, and triggering automatic responses such as the opening and closing of ion channels. The purpose of this project was to learn how to replicate simple threat detection and response functions within artificial membrane systems. The original goals toward developing 'smart skin' assemblies included: (1) synthesizing functionalized nanoparticles to produce electrochemically responsive systems within a lipid bilayer host matrices, (2) calculating the energetics of nanoparticle-lipid interactions and pore formation, and (3) determining the mechanism of insertion of nanoparticles in lipid bilayers via imaging and electrochemistry. There are a few reports of the use of programmable materials to open and close pores in rigid hosts such as mesoporous materials using either heat or light activation. However, none of these materials can regulate themselves in response to the detection of threats. The strategies we investigated in this project involve learning how to use programmable nanomaterials to automatically eliminate open channels within a lipid bilayer host when 'threats' are detected. We generated and characterized functionalized nanoparticles that can be used to create synthetic pores through the membrane and investigated methods of eliminating the pores either through electrochemistry, change in pH, etc. We also focused on characterizing the behavior of functionalized gold NPs in different lipid membranes and lipid vesicles and coupled these results to modeling efforts designed to gain an understanding of the interaction of nanoparticles within lipid assemblies.

Montano, Gabriel A.; Xiao, Xiaoyin; Achyuthan, Komandoor E.; Allen, Amy; Brozik, Susan Marie; Edwards, Thayne L.; Frischknecht, Amalie Lucile; Wheeler, David Roger

2011-09-01T23:59:59.000Z

126

Human Factors Engineering Program Review Model (NUREG-0711)Revision 3: Update Methodology and Key Revisions  

SciTech Connect (OSTI)

The U.S. Nuclear Regulatory Commission (NRC) reviews the human factors engineering (HFE) programs of applicants for nuclear power plant construction permits, operating licenses, standard design certifications, and combined operating licenses. The purpose of these safety reviews is to help ensure that personnel performance and reliability are appropriately supported. Detailed design review procedures and guidance for the evaluations is provided in three key documents: the Standard Review Plan (NUREG-0800), the HFE Program Review Model (NUREG-0711), and the Human-System Interface Design Review Guidelines (NUREG-0700). These documents were last revised in 2007, 2004 and 2002, respectively. The NRC is committed to the periodic update and improvement of the guidance to ensure that it remains a state-of-the-art design evaluation tool. To this end, the NRC is updating its guidance to stay current with recent research on human performance, advances in HFE methods and tools, and new technology being employed in plant and control room design. NUREG-0711 is the first document to be addressed. We present the methodology used to update NUREG-0711 and summarize the main changes made. Finally, we discuss the current status of the update program and the future plans.

OHara J. M.; Higgins, J.; Fleger, S.

2012-07-22T23:59:59.000Z

127

Smart Thermal Skins for Vehicles  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

8 8 Smart Thermal Skins for Vehicles With a modest effort, many of the energy-efficient technologies developed for buildings can be transferred to the transportation sector. The goal of vehicle thermal management research at LBL is to save the energy equivalent of one to two billion gallons of gasoline per year, and improve the marketability of next-generation vehicles using advanced solar control glazings and insulating shell components to reduce accessory loads. Spectrally selective and electrochromic window glass and lightweight insulating materials improve the fuel efficiency of conventional and hybrid vehicles and extend the range of electric vehicles by reducing the need for air conditioning and heating, and by allowing the downsizing of equipment.

128

NREL: Vehicle Ancillary Loads Reduction - Physiological Model  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Physiological Model Physiological Model The Vehicle Ancillary Loads Reduction team developed a three-dimensional model to simulate human internal thermal physiological systems (muscle, blood, etc.) and thermoregulatory responses such as metabolic heat generation. The model was developed with ANSYS, a finite element software which computes heat flow by conduction, convection, and mass transport of the blood. A human tissue system model represents the human body, including the physiological and thermal properties of the tissues. The arms and legs consist of bone, muscle, fat, and skin. There are additional lung, abdominal, and brain tissues in the torso and head zones. The model calculates the conduction heat transfer based on the temperature gradients between the tissue nodes. Blood flow is modeled with a network of supply

129

Thermal comfort, skin temperature distribution, and sensible heat loss distribution in the sitting posture in various asymmetric radiant fields  

Science Journals Connector (OSTI)

This study aimed at investigating the thermal comfort for the whole body as well as for certain local areas, skin temperatures, and sensible heat losses in various asymmetric radiant fields. Human subject experiments were conducted to assess the overall comfort sensation and local discomfort, and local skin temperatures were measured. Through thermal manikin experiments, we discovered a new method for the precise measurement of the local sensible heat loss in nonuniform thermal environments. The local sensible heat losses were measured by the use of a thermal manikin that had the same local skin temperatures as the human subjects. The experimental conditions consisted of the anterior–posterior, right–left, and up–down asymmetric thermal environments created by radiation panels. A total of 35 thermal environmental conditions were created ranging from 25.5 to 30.5 °C for air temperature, from 11.5 to 44.5 °C for surface temperature of radiation panels, from 40% RH to 50% RH for humidity, and less than 0.05 m/s for inlet air velocity to the climatic chamber. The local skin temperature changed depending on the environmental thermal nonuniformity, even if the mean skin temperature remained almost the same. It is essential to use the skin temperature distribution as well as mean skin temperature for expressing thermal comfort in nonuniform environments. The local sensible heat loss changed depending on the environmental thermal nonuniformity, even if the mean sensible heat loss remained almost the same. The relationship between the local skin temperature and local sensible heat loss cannot be depicted by a simple line; instead, it varies depending on the environmental thermal nonuniformity. The local heat discomfort in the head area was dependent on both the local skin temperature and local sensible heat loss. However, the local cold discomfort in the foot area was related only to the local skin temperature.

Tomonori Sakoi; Kazuyo Tsuzuki; Shinsuke Kato; Ryozo Ooka; Doosam Song; Shengwei Zhu

2007-01-01T23:59:59.000Z

130

Skin-Like Prosthetic Polymer Surfaces - Energy Innovation Portal  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

mimic skin. ORNL scientists combined superhydrophobic polymer inventions with carbon nanotubes to create a self-cleaning skin-like surface material with the ability to transmit...

131

Repair of UV Dimers in Skin DNA of Patients with Basal Cell Carcinoma  

Science Journals Connector (OSTI)

...carcinoma have a reduced capacity to repair UV-induced...after a brief exposure to solar-simulated UV radiation...Therefore, a reduced capacity to repair photolesions...induced in human skin by solar-simulating UV radiation...Grossman L. DNA repair capacity for ultraviolet light-induced...

Dan Segerbäck; Malgorzata Strozyk; Erna Snellman; and Kari Hemminki

2008-09-01T23:59:59.000Z

132

From DNA Sequence Analysis to Modeling Replication in the Human Genome  

Science Journals Connector (OSTI)

We explore the large-scale behavior of nucleotide compositional strand asymmetries along human chromosomes. As we observe for 7 of 9 origins of replication experimentally identified so far, the (TA+GC) skew displays rather sharp upward jumps, with a linear decreasing profile in between two successive jumps. We present a model of replication with well positioned replication origins and random terminations that accounts for the observed characteristic serrated skew profiles. We succeed in identifying 287 pairs of putative adjacent replication origins with an origin spacing ?1–2??Mbp that are likely to correspond to replication foci observed in interphase nuclei and recognized as stable structures that persist throughout subsequent cell generations.

E. B. Brodie of Brodie; S. Nicolay; M. Touchon; B. Audit; Y. d’Aubenton-Carafa; C. Thermes; A. Arneodo

2005-06-23T23:59:59.000Z

133

earth skin temperature | OpenEI  

Open Energy Info (EERE)

earth skin temperature earth skin temperature Dataset Summary Description (Abstract): Earth Skin Temperature (° C)NASA Surface meteorology and Solar Energy (SSE) Release 6.0 Data Set (Nov 2007)22-year Monthly & Annual Average (July 1983 - June 2005)Parameter: Earth Skin Temperature (deg C)Internet: http://eosweb.larc.nasa.gov/sse/Note 1: SSE Methodology & Accuracy sections onlineNote 2: Lat/Lon values indicate the lower left corner of a 1x1 degree region. Negative values are south and west; positive values are north and east. Boundaries of the -90/-180 region Source U.S. National Aeronautics and Space Administration (NASA), Surface meteorology and Solar Energy (SSE) Date Released March 31st, 2009 (5 years ago) Date Updated April 01st, 2009 (5 years ago) Keywords climate

134

Active skin for turbulent drag reduction  

E-Print Network [OSTI]

evidence that spanwise traveling waves of the right amplitude, wavelength and frequency can result in significant turbulent drag reduction. Such traveling waves can be induced in the smart skin via active-material actuation. The flow control technique...

Mani, Raghavendran

2002-01-01T23:59:59.000Z

135

A dynamic evolution model of human opinion as affected by advertising  

Science Journals Connector (OSTI)

Abstract We propose a new model to investigate the dynamics of human opinion as affected by advertising, based on the main idea of the CODA model and taking into account two practical factors: one is that the marginal influence of an additional friend will decrease with an increasing number of friends; the other is the decline of memory over time. Simulations show several significant conclusions for both advertising agencies and the general public. A small difference of advertising’s influence on individuals or advertising coverage will result in significantly different advertising effectiveness within a certain interval of value. Compared to the value of advertising’s influence on individuals, the advertising coverage plays a more important role due to the exponential decay of memory. Meanwhile, some of the obtained results are in accordance with people’s daily cognition about advertising. The real key factor in determining the success of advertising is the intensity of exchanging opinions, and people’s external actions always follow their internal opinions. Negative opinions also play an important role.

Gui-Xun Luo; Yun Liu; Qing-An Zeng; Su-Meng Diao; Fei Xiong

2014-01-01T23:59:59.000Z

136

Modeling and analysis of affective influences on human experience, prediction, decision making, and behavior  

E-Print Network [OSTI]

Subjective and affective elements are well-known to influence human decision making. This dissertation presents a theoretical and empirical framework on how human decision makers' subjective experience and affective ...

Ahn, Hyungil, 1976-

2010-01-01T23:59:59.000Z

137

A Multi-Methods Approach to HRA and Human Performance Modeling: A Field Assessment  

SciTech Connect (OSTI)

The Advanced Test Reactor (ATR) is a research reactor at the Idaho National Laboratory is primarily designed and used to test materials to be used in other, larger-scale and prototype reactors. The reactor offers various specialized systems and allows certain experiments to be run at their own temperature and pressure. The ATR Canal temporarily stores completed experiments and used fuel. It also has facilities to conduct underwater operations such as experiment examination or removal. In reviewing the ATR safety basis, a number of concerns were identified involving the ATR canal. A brief study identified ergonomic issues involving the manual handling of fuel elements in the canal that may increase the probability of human error and possible unwanted acute physical outcomes to the operator. In response to this concern, that refined the previous HRA scoping analysis by determining the probability of the inadvertent exposure of a fuel element to the air during fuel movement and inspection was conducted. The HRA analysis employed the SPAR-H method and was supplemented by information gained from a detailed analysis of the fuel inspection and transfer tasks. This latter analysis included ergonomics, work cycles, task duration, and workload imposed by tool and workplace characteristics, personal protective clothing, and operational practices that have the potential to increase physical and mental workload. Part of this analysis consisted of NASA-TLX analyses, combined with operational sequence analysis, computational human performance analysis (CHPA), and 3D graphical modeling to determine task failures and precursors to such failures that have safety implications. Experience in applying multiple analysis techniques in support of HRA methods is discussed.

Jacques Hugo; David I Gertman

2012-06-01T23:59:59.000Z

138

The skin's role in human thermoregulation and comfort  

E-Print Network [OSTI]

interactions and phase change in fibrous material B. Jmaterials Sources of further information and advice References Phase change

Arens, Edward A; Zhang, H.

2006-01-01T23:59:59.000Z

139

Uneven distribution of aerobic mesophilic bacteria on human skin.  

Science Journals Connector (OSTI)

...Fig. 1) consists ofa clock electric motor, an electric impulse counter...60 times per min by the clock electric motor. After the first 1 ml was removed...7) on/offswitch; (8) electric motor; (9) support stand; (10...

W A Keith Jr; R J Smiljanic; W A Akers; L W Keith

1979-02-01T23:59:59.000Z

140

Trichophyton eboreum sp. nov. Isolated from Human Skin  

Science Journals Connector (OSTI)

...Krajden, and G. Land. 1997. Laboratory handbook of dermatophytes. Star Publishing Company...and G. Land (ed.), Laboratory handbook of dermatophytes. Star Publishing Company...and G. Land (ed.), Laboratory handbook of dermatophytes. Star Publishing Company...

Jochen Brasch; Yvonne Gräser

2005-10-01T23:59:59.000Z

Note: This page contains sample records for the topic "human skin model" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


141

Computational Modeling of Human Head Under Blast Shailesh Ganpule, Dr. Linxia Gu, Dr. Guoxin Cao, Dr.Namas Chandra  

E-Print Network [OSTI]

Computational Modeling of Human Head Under Blast Loading Shailesh Ganpule, Dr. Linxia Gu, Dr;Presentation Objective: To understand role of helmet in blast induced Traumatic Brain Injury (TBI: To understand underlying mechanisms of blast induced Traumatic Brain Injury (TBI) and develop mitigation

Farritor, Shane

142

Mislocalization and Degradation of Human P23H-Rhodopsin-GFP in a Knockin Mouse Model of  

E-Print Network [OSTI]

in the inner segments of the frog rod cells, but does not form aggregates.9 Retention of P23HMislocalization and Degradation of Human P23H-Rhodopsin-GFP in a Knockin Mouse Model of Retinitis the effects of treatments on degradation and mislo- calization of proline-to-histidine change at codon 23 (P23

Wensel, Theodore G.

143

Liu, Z., H.C. Frey, Y. Cao, and B. Deshpande, "Modeling of In-vehicle PM2.5 Exposure Using the Stochastic Human Exposure and Dose Simulation Model," Paper 2009-A-238-AWMA, Proceedings, 102nd  

E-Print Network [OSTI]

the Stochastic Human Exposure and Dose Simulation Model," Paper 2009-A-238-AWMA, Proceedings, 102nd Annual of In-vehicle PM2.5 Exposure Using the Stochastic Human Exposure and Dose Simulation Model Paper: 2009-A in the current version of Stochastic Exposure and Dose Simulation model for Particulate Matter (SHEDS-PM) for in

Frey, H. Christopher

144

The environmental protection agency's research program on total human exposure  

Science Journals Connector (OSTI)

The U.S. Environmental Protection Agency's (U.S. EPA) research program on total human exposure to environmental pollution seeks to develop a newly emerging concept in the environmental sciences. Instead of focusing purely on the sources of pollution or their transport and movement through the environment, this research focuses on human beings as the receptors of these pollutants. People and daily activities become the center of attention. The methodology measures and models the pollutant concentrations found at the physical boundaries of people, regardless of whether the pollutants arrive through the air, water, food, or skin. It seeks to characterize quantitatively the impact of pollution on people by determining if an environmental problem exists at the human interface and, if so, by determining the sources, nature, extent, and severity of this environmental problem. By exploiting an emerging new arsenal of miniaturized instruments and by developing statistically representative survey designs for sampling the population of cities, significant progress has been made in recent years in providing previously unavailable human exposure field data needed for making valid risk assessments. The U.S. EPA total human exposure research program includes: development of measurement methods and instruments, development of exposure models and statistical protocols, microenvironmental field studies, total human exposure studies, validation of human exposure models with empirical data, and dosage research investigations.

Wayne Ott; Lance Wallace; David Mage; Gerald Akland; Robert Lewis; Harold Sauls; Charles Rodes; David Kleffman; Donna Kuroda; Karen Morehouse

1986-01-01T23:59:59.000Z

145

Picropodophyllin inhibits tumor growth of human nasopharyngeal carcinoma in a mouse model  

SciTech Connect (OSTI)

Highlights: •We identified that PPP inhibits IGF-1R/Akt pathway in NPC cells. •PPP dose-dependently inhibits NPC cell proliferation in vitro. •PPP suppresses tumor growth of NPC in nude mice. •PPP have little effect on microtubule assembly. -- Abstract: Insulin-like growth factor-1 receptor (IGF-1R) is a cell membrane receptor with tyrosine kinase activity and plays important roles in cell transformation, tumor growth, tumor invasion, and metastasis. Picropodophyllin (PPP) is a selective IGF-1R inhibitor and shows promising antitumor effects for several human cancers. However, its antitumor effects in nasopharyngeal carcinoma (NPC) remain unclear. The purpose of this study is to investigate the antitumor activity of PPP in NPC using in vitro cell culture and in vivo animal model. We found that PPP dose-dependently decreased the IGF-induced phosphorylation and activity of IGF-1R and consequently reduced the phosphorylation of Akt, one downstream target of IGF-1R. In addition, PPP inhibited NPC cell proliferation in vitro. The half maximal inhibitory concentration (IC50) of PPP for NPC cell line CNE-2 was ?1 ?M at 24 h after treatment and ?0.5 ?M at 48 h after treatment, respectively. Moreover, administration of PPP by intraperitoneal injection significantly suppressed the tumor growth of xenografted NPC in nude mice. Taken together, these results suggest targeting IGF-1R by PPP may represent a new strategy for treatment of NPCs with positive IGF-1R expression.

Yin, Shu-Cheng [Department of Otolaryngology – Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan 430060 (China) [Department of Otolaryngology – Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan 430060 (China); Department of Otolaryngology – Head and Neck Surgery, Zhongnan Hospital of Wuhan University, Wuhan 430071 (China); Guo, Wei [Department of Otolaryngology – Head and Neck Surgery, Zhongnan Hospital of Wuhan University, Wuhan 430071 (China)] [Department of Otolaryngology – Head and Neck Surgery, Zhongnan Hospital of Wuhan University, Wuhan 430071 (China); Tao, Ze-Zhang, E-mail: zezhangtao@gmail.com [Department of Otolaryngology – Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan 430060 (China)] [Department of Otolaryngology – Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan 430060 (China)

2013-09-13T23:59:59.000Z

146

Extending the Use of Evacuation Simulators to Support Counter Terrorism: Using Models of Human Behaviour to Coordinate Emergency Responses to Improvised Explosive Devices  

E-Print Network [OSTI]

Extending the Use of Evacuation Simulators to Support Counter Terrorism: Using Models of Human; evacuation; security; counter terrorism Abstract Software simulations have been widely used to model the risk assessments that drive counter terrorism. Two key areas are discussed; changes in the human

Johnson, Chris

147

Modeling Measuring and Correcting the LCA of theModeling Measuring and Correcting the LCA of the Human EyeHuman Eye  

E-Print Network [OSTI]

Modeling Measuring and Correcting the LCA of theModeling Measuring and Correcting the LCA aberration (LCA) and transverse chromatic aberration (TCA). In the presence of polychromatic light, these two types of chromatic aberrations have an impact on the retinal image. Studied isolated, both the LCA

Ribak, Erez

148

The gentle touch receptors of mammalian skin  

Science Journals Connector (OSTI)

...musical symphony of neural impulses that the brain translates as a touch. Each LTMR end...neural dialogue between the skin and the brain. The challenge for future research is...represented and processed in the spinal cord and brain and enables the richness of touch perceptions...

Amanda Zimmerman; Ling Bai; David D. Ginty

2014-11-21T23:59:59.000Z

149

Self-cleaning skin-like prosthetic polymer surfaces  

DOE Patents [OSTI]

An external covering and method of making an external covering for hiding the internal endoskeleton of a mechanical (e.g., prosthetic) device that exhibits skin-like qualities is provided. The external covering generally comprises an internal bulk layer in contact with the endoskeleton of the prosthetic device and an external skin layer disposed about the internal bulk layer. The external skin layer is comprised of a polymer composite with carbon nanotubes embedded therein. The outer surface of the skin layer has multiple cone-shaped projections that provide the external skin layer with superhydrophobicity. The carbon nanotubes are preferably vertically aligned between the inner surface and outer surface of the external skin layer in order to provide the skin layer with the ability to transmit heat. Superhydrophobic powders may optionally be used as part of the polymer composite or applied as a coating to the surface of the skin layer to enhance superhydrophobicity.

Simpson, John T. (Clinton, TN); Ivanov, Ilia N. (Knoxville, TN); Shibata, Jason (Manhattan Beach, CA)

2012-03-27T23:59:59.000Z

150

Light & Skin Interactions: Simulations for Computer Graphics Applications  

Science Journals Connector (OSTI)

Light & Skin Interactions immerses you in one of the most fascinating application areas of computer graphics: appearance simulation. The book first illuminates the fundamental biophysical processes that affect skin appearance, and reviews seminal ...

Gladimir V. G. Baranoski; Aravind Krishnaswamy

2010-05-01T23:59:59.000Z

151

Human capital composition, growth and development: an R&D growth model versus data  

Science Journals Connector (OSTI)

The effect of human capital composition on growth and development has been somewhat neglected in economic literature. However, evidence has suggested the importance of engineering and technical (high-tech) ski...

Tiago Neves Sequeira

2007-04-01T23:59:59.000Z

152

An HMM-based boundary-flexible model of human haplotype variation  

E-Print Network [OSTI]

The construction of a meaningful and detailed description of haplotype variation holds the promise for more powerful genetic association studies. The segmentation of the human genome into blocks of limited haplotype diversity ...

Sheffi, Jonathan, 1981-

2004-01-01T23:59:59.000Z

153

Human-machine interactions  

SciTech Connect (OSTI)

Digital technology utilizing a cognitive model based on human naturalistic decision-making processes, including pattern recognition and episodic memory, can reduce the dependency of human-machine interactions on the abilities of a human user and can enable a machine to more closely emulate human-like responses. Such a cognitive model can enable digital technology to use cognitive capacities fundamental to human-like communication and cooperation to interact with humans.

Forsythe, J. Chris (Sandia Park, NM); Xavier, Patrick G. (Albuquerque, NM); Abbott, Robert G. (Albuquerque, NM); Brannon, Nathan G. (Albuquerque, NM); Bernard, Michael L. (Tijeras, NM); Speed, Ann E. (Albuquerque, NM)

2009-04-28T23:59:59.000Z

154

Exact volume preserving skinning with shape control Damien Rohmer1,2  

E-Print Network [OSTI]

skinning, perfectly fits into the usual production pipeline. It can be used whatever the desired locality the way rubber-like materials and organic shapes respectively deform can be modeled. An improved algorithm is a complex process, which needs to fit into the standard production pipe-line for efficient use by artists

Paris-Sud XI, Université de

155

Abstract 4592: Etirinotecan pegol accumulates in breast cancer brain metastases and prolongs survival in an experimental model of brain metastases of human triple negative breast cancer  

Science Journals Connector (OSTI)

...Etirinotecan pegol accumulates in breast cancer brain metastases and prolongs survival in an experimental model of brain metastases of human triple negative breast...Morgantown, WV. Background: Breast cancer brain metastases (BCBM) remain a challenging...

Mohamed Nounou; Ute Hoch; Chris E. Adkins; Tori B. Terrell; Heidi Villalba; Michael E. Eldon; Paul R. Lockman

2014-10-01T23:59:59.000Z

156

Generative models of rich clubs in Hebbian neuronal networks and large-scale human brain networks  

Science Journals Connector (OSTI)

...Theme Issue Complex network theory and the brain compiled and edited by David Papo, Javier...neuronal networks and large-scale human brain networks Petra E. Vertes 1 Aaron Alexander-Bloch...Theme Issue Complex network theory and the brain . Rich clubs arise when nodes that are...

2014-01-01T23:59:59.000Z

157

Essays on econometric modeling of subjective perceptions of risks in environment and human health  

E-Print Network [OSTI]

A large body of literature studies the issues of the option price and other ex-ante welfare measures under the microeconomic theory to valuate reductions of risks inherent in environment and human health. However, it does not offer a careful...

Nguyen, To Ngoc

2009-05-15T23:59:59.000Z

158

Animatable Human Body Model Reconstruction from 3D Scan Data using Templates  

E-Print Network [OSTI]

, we propose a recon- struction pipeline which solves these three prob- lems by fitting a template to be established, which is a time-consuming process. Lee et al. [1] repair the scanned surface of human faces 1: High-level overview of the reconstruction pipeline fitting strategies (where holes are filled

Veltkamp, Remco

159

Structure, function and diversity of the healthy human microbiome  

E-Print Network [OSTI]

Studies of the human microbiome have revealed that even healthy individuals differ remarkably in the microbes that occupy habitats such as the gut, skin and vagina. Much of this diversity remains unexplained, although diet, ...

Alm, Eric J.

160

NREL: Vehicle Ancillary Loads Reduction - Thermal Comfort Model  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Comfort Model Comfort Model Photo of human testing to determine thermal comfort perception data. Photo of human testing to determine thermal comfort perception data. Working with researchers at the University of California, Berkeley, our team at NREL developed an empirical model of people's temperature sensation (hot/cold) as well as perceptions (comfortable/uncomfortable) in a transient non-homogeneous environment. The model predicts sensation and comfort locally (at specific points on the body) as well as globally (overall). The university performed more than 100 tests on human test subjects in a controlled environmental chamber under a range of steady state and transient thermal conditions. Participants subjectively recorded their thermal comfort on a simple form. Core and local skin temperature data was

Note: This page contains sample records for the topic "human skin model" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


161

Estimating cancer risk from dental cone-beam CT exposures based on skin dosimetry  

Science Journals Connector (OSTI)

The aim of this study was to measure entrance skin doses on patients undergoing cone-beam computed tomography (CBCT) examinations, to establish conversion factors between skin and organ doses, and to estimate cancer risk from CBCT exposures. 266 patients (age 8–83) were included, involving three imaging centres. CBCT scans were acquired using the SCANORA 3D (Soredex, Tuusula, Finland) and NewTom 9000 (QR, Verona, Italy). Eight thermoluminescent dosimeters were attached to the patient's skin at standardized locations. Using previously published organ dose estimations on various CBCTs with an anthropomorphic phantom, correlation factors to convert skin dose to organ doses were calculated and applied to estimate patient organ doses. The BEIR VII age- and gender-dependent dose-risk model was applied to estimate the lifetime attributable cancer risk. For the SCANORA 3D, average skin doses over the eight locations varied between 484 and 1788 µGy. For the NewTom 9000 the range was between 821 and 1686 µGy for Centre 1 and between 292 and 2325 µGy for Centre 2. Entrance skin dose measurements demonstrated the combined effect of exposure and patient factors on the dose. The lifetime attributable cancer risk, expressed as the probability to develop a radiation-induced cancer, varied between 2.7 per million (age >60) and 9.8 per million (age 8–11) with an average of 6.0 per million. On average, the risk for female patients was 40% higher. The estimated radiation risk was primarily influenced by the age at exposure and the gender, pointing out the continuing need for justification and optimization of CBCT exposures, with a specific focus on children.

Ruben Pauwels; Lesley Cockmartin; Deimante Ivanauskaité; Ausra Urbonien?; Sophia Gavala; Catherine Donta; Kostas Tsiklakis; Reinhilde Jacobs; Hilde Bosmans; Ria Bogaerts; Keith Horner; The SEDENTEXCT Project Consortium

2014-01-01T23:59:59.000Z

162

COMPUTATIONAL DOSIMETRY FOR CHILD AND ADULT HUMAN MODELS DUE TO CONTACT CURRENT FROM 10 HZ TO 110 MHZ  

Science Journals Connector (OSTI)

......effect was in the heart. With respect to brain and skin conductivities, one needs to...is discussed in (29). With respect to brain tissue, Peters and Stinstra(30) reported...in (22) was chosen as the estimate of brain conductivity. The value reported subsequently......

Kwok Hung Chan; Shunya Ohta; Ilkka Laakso; Akimasa Hirata; Yukihisa Suzuki; Robert Kavet

2014-10-01T23:59:59.000Z

163

Risk Group, Skin Lesion History, and Sun Sensitivity Reliability in Squamous Cell Skin Cancer Progression  

Science Journals Connector (OSTI)

...Skin tanning characteristics 0.207 Always burns, no tan 11 (14.1) 7 (21.2) 5 (15.6) 23 (16.1) Always burns, tans minimally 16 (20.5) 11 (33.3) 9 (28.1) 36 (25.2) Burns moderately 28 (35.9) 7 (21.2) 13...

Mary C. Clouser; Robin B. Harris; Denise J. Roe; Kathylynn Saboda; James Ranger-Moore; Laura Duckett; and David S. Alberts

2006-11-01T23:59:59.000Z

164

Hypercontraction and Drosophila : a model system for the study of human myopathies  

E-Print Network [OSTI]

Currently, there are no therapeutic interventions which fully alleviate the defects associated with muscular dystrophies and cardiomyopathies. Development of model systems in which to utilize high-throughput screens for ...

Montana, Enrico Sakai

2005-01-01T23:59:59.000Z

165

r Human Brain Mapping 30:18771886 (2009) r Dynamic GrangerGeweke Causality Modeling  

E-Print Network [OSTI]

requires a measure of effective connectivity. Previ- ously, structural equation modeling (SEM) has been, Roosevelt Rd., Taipei 106, Taiwan. E-mail: fhlin@ntu.edu.tw or fhlin@nmr.mgh.harvard.edu Received

166

Simulating the physiology of athletes during endurance sports events: modelling human energy conversion and metabolism  

Science Journals Connector (OSTI)

...computational model of energy turnover and heat transport...in the phosphocreatine energy buffer status can be predicted, although...central metabolism allows us to investigate hypotheses...main fates of metabolic energy converted in the muscle...

2011-01-01T23:59:59.000Z

167

Agent-based modeling: Methods and techniques for simulating human systems  

Science Journals Connector (OSTI)

...loopholes as possible, to prevent abuses by devious players. The model...transactions. Shopbots are Internet agents that automatically search...Corporation has simulated the Internet service provider (ISP) market...Bios and Cap Gemini Ernst & Young (13) have applied ABM techniques...

Eric Bonabeau

2002-01-01T23:59:59.000Z

168

Robust modelling, measurement and analysis of human and animal metabolic systems  

Science Journals Connector (OSTI)

...computational model analysis of the measured...analysed with a computer package called...the metabolic system of interest...implemented as a computer package realized...common operating systems such as MS Windows...Pentium-based desktop computer. Parallelization...combination with analysis and flux estimation...

2009-01-01T23:59:59.000Z

169

IMEKO TC 18 Symposium Measurement, Analysis and Modelling of Human Functions  

E-Print Network [OSTI]

, a reduced order model is derived; whose inputs are wheel orientations, lateral force and yaw moment. Because of the sinusoidal regression after the frequency analysis. The yaw moment that cannot be measured in our motion measurement system is identified based on computer simulations; whose result is made to be matched

Ito, Satoshi

170

Complexity of Structure Mapping in Human Analogical Reasoning: A PDP Model  

E-Print Network [OSTI]

-water flow, and atom-solar system, while remaining within capacity limitations. Introduction The growth to incorporate psychologically realistic processing capacity limitations. Capacity is defined in terms are superimposed. Based on empirical evidence of capacity limitations, the model is limited to processing one

Wilson, Bill

171

Measurement and bio-dynamic model development of seated human subjects exposed to low frequency vibration environment  

Science Journals Connector (OSTI)

In this study, the effect of posture, vibration magnitude and frequency on seat-to-head (STH) and back support-to-head (BTH) transfer functions has been studied under vertical sinusoidal vibration. Twelve healthy male subjects participated in experimental work to measure vertical vibration transmitted to the occupants' heads in three representative postures (erect, vertical backrest and forward lean on table) under three magnitudes of vibration (0.4, 0.8 and 1.2 m/s² r.m.s.) in frequency range 1 to 20 Hz. From collected data sets, the effects of vibration magnitude, vibration frequency and postures on STH and BTH transmissibility and phase were measured over the prescribed frequency range. The result suggested that inclusion of all possible variables in optimal design of vehicle seat, suspension and comfort analysis would improve the design and analysis. The comparison of experimental and model response reveals that both models matched with mean experimental data sets most closely and the models provide the best description of the biodynamic response of seated human subjects under vertical whole body vibration.

S.P. Harsha; Milk Desta; A.S. Prashanth; V.H. Saran

2014-01-01T23:59:59.000Z

172

Skin cancer detection by oblique-incidence diffuse reflectance spectroscopy  

E-Print Network [OSTI]

Skin cancer is the most common form of cancer and it is on the rise. If skin cancer is diagnosed early enough, the survival rate is close to 90%. Oblique-incidence diffuse reflectance (OIR) spectroscopy offers a technology that may be used...

Smith, Elizabeth Brooks

2009-05-15T23:59:59.000Z

173

Neutron skin of 208 Pb in consistency with  

E-Print Network [OSTI]

Neutron skin of 208 Pb in consistency with neutron star observations K. Miyazaki E-mail: miyazakiro as varying the neutron radius of 208Pb. The neutron skin thickness Sn is determined in the comparison with the astronomical observations of massive neutron stars (NSs), the standard scenario of NS cooling

174

Prediction modeling of physiological responses and human performance in the heat  

Science Journals Connector (OSTI)

Over the last two decades, our laboratory has been establishing the data base and developing a series of predictive equations for deep body temperature, heart rate and sweat loss responses of clothed soldiers performing physical work at various environmental extremes. Individual predictive equations for rectal temperature, heart rate and sweat loss as a function of the physical work intensity, environmental conditions and particular clothing ensemble have been published in the open literature. In addition, important modifying factors such as energy expenditure, state of heat acclimation and solar heat load have been evaluated and appropriate predictive equations developed. Currently, we have developed a comprehensive model which is programmed on a Hewlett-Packard 41 CV hand held calculator. The primary physiological inputs are deep body (rectal) temperature and sweat loss while the predicted outputs are the expected physical work-rest cycle, the maximum single physical work time if appropriate, and the associated water requirements. This paper presents the mathematical basis employed in the development of the various individual predictive equations of our heat stress model. In addition, our current heat stress prediction model as programmed on the HP 41 CV is discussed from the standpoint of propriety in meeting the Army's needs and therefore assisting in military mission accomplishment.

Kent B. Pandolf; Leander A. Stroschein; Lawrence L. Drolet; Richard R. Gonzalez; Michael N. Sawka

1986-01-01T23:59:59.000Z

175

Method and apparatus to measure the depth of skin burns  

DOE Patents [OSTI]

A new device for measuring the depth of surface tissue burns based on the rate at which the skin temperature responds to a sudden differential temperature stimulus. This technique can be performed without physical contact with the burned tissue. In one implementation, time-dependent surface temperature data is taken from subsequent frames of a video signal from an infrared-sensitive video camera. When a thermal transient is created, e.g., by turning off a heat lamp directed at the skin surface, the following time-dependent surface temperature data can be used to determine the skin burn depth. Imaging and non-imaging versions of this device can be implemented, thereby enabling laboratory-quality skin burn depth imagers for hospitals as well as hand-held skin burn depth sensors the size of a small pocket flashlight for field use and triage.

Dickey, Fred M. (Albuquerque, NM); Holswade, Scott C. (Albuquerque, NM)

2002-01-01T23:59:59.000Z

176

E-Print Network 3.0 - avoidable skin cancers Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Sample search results for: avoidable skin cancers Page: << < 1 2 3 4 5 > >> 1 "Skin Cancer-What to Look For" Rochester Recreation Summary: "Skin Cancer- What to Look For"...

177

Mechanistic investigation of skin barrier perturbation induced by surfactants in the presence of humectants  

E-Print Network [OSTI]

The stratum corneum (SC) of the skin functions as a barrier between the body and the environment. Surfactants such as Sodium Dodecyl Sulfate (SDS) are used in skin cleansers and in skin-care formulations because of their ...

Ghosh, Saswata

2007-01-01T23:59:59.000Z

178

Gender differences in skin: A review of the literature  

Science Journals Connector (OSTI)

Background: There has been increasing interest in studying gender differences in skin to learn more about disease pathogenesis and to discover more effective treatments. Recent advances have been made in our understanding of these differences in skin histology, physiology, and immunology, and they have implications for diseases such as acne, eczema, alopecia, skin cancer, wound healing, and rheumatologic diseases with skin manifestations. Objective: This article reviews advances in our understanding of gender differences in skin. Methods: Using the PubMed database, broad searches for topics, with search terms such as gender differences in skin and sex differences in skin, as well as targeted searches for gender differences in specific dermatologic diseases, such as gender differences in melanoma, were performed. Additional articles were identified from cited references. Articles reporting gender differences in the following areas were reviewed: acne, skin cancer, wound healing, immunology, hair/alopecia, histology and skin physiology, disease-specific gender differences, and psychological responses to disease burden. Results: A recurring theme encountered in many of the articles reviewed referred to a delicate balance between normal and pathogenic conditions. This theme is highlighted by the complex interplay between estrogens and androgens in men and women, and how changes and adaptations with aging affect the disease process. Sex steroids modulate epidermal and dermal thickness as well as immune system function, and changes in these hormonal levels with aging and/or disease processes alter skin surface pH, quality of wound healing, and propensity to develop autoimmune disease, thereby significantly influencing potential for infection and other disease states. Gender differences in alopecia, acne, and skin cancers also distinguish hormonal interactions as a major target for which more research is needed to translate current findings to clinically significant diagnostic and therapeutic applications. Conclusions: The published findings on gender differences in skin yielded many advances in our understanding of cancer, immunology, psychology, skin histology, and specific dermatologic diseases. These advances will enable us to learn more about disease pathogenesis, with the goal of offering better treatments. Although gender differences can help us to individually tailor clinical management of disease processes, it is important to remember that a patient's sex should not radically alter diagnostic or therapeutic efforts until clinically significant differences between males and females arise from these findings. Because many of the results reviewed did not originate from randomized controlled clinical trials, it is difficult to generalize the data to the general population. However, the pressing need for additional research in these areas becomes exceedingly clear, and there is already a strong foundation on which to base future investigations.

Harry Dao Jr.; Rebecca A. Kazin

2007-01-01T23:59:59.000Z

179

Special Issue on Human Computing  

E-Print Network [OSTI]

The seven articles in this special issue focus on human computing. Most focus on two challenging issues in human computing, namely, machine analysis of human behavior in group interactions and context-sensitive modeling.

Nijholt, Anton

180

Carrier-mediated transport of monocarboxylic acids in BeWo cell monolayers as a model of the human trophoblast  

E-Print Network [OSTI]

The monolayer-forming, human choriocarcinoma cell line, BeWo, was used to study the mechanisms of monocarboxylic acid transport across the human trophoblast. Benzoic acid, acetic acid, and lactic acid were used as markers ...

Utoguchi, Naoki; Magnusson, Malin; Audus, Kenneth L.

1999-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "human skin model" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


181

Skin Disease In Dermatomyositis -- What Patients And Their Families Often Want To Know  

E-Print Network [OSTI]

on the upper eyelids (heliotrope erythema), the cheeks ofcharacteristic violet (heliotrope) skin color seen in whitecharacteristic violet (heliotrope) skin color seen in white

Sontheimer, Richard D.

2002-01-01T23:59:59.000Z

182

E-Print Network 3.0 - anomalous skin effect Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

skin detector. Row 2(a) illustrates the effect of occlusion and rotational... Skin Patch Detection in Real-World Images Hannes Kruppa, Martin A. Bauer and Bernt Schiele... :...

183

Prostate Pathology of Genetically Engineered Mice: Definitions and Classification. The Consensus Report from the Bar Harbor Meeting of the Mouse Models of Human Cancer Consortium Prostate Pathology Committee  

Science Journals Connector (OSTI)

...interpretation of the origin and natural history of their diseases. The recommended...alter the phenotype or natural history of lesion progression in existing...alter the phenotype or natural history of lesion progression in existing...Disease Models, Animal Genetic Engineering Humans Male Mice Mice, Knockout...

Scott B. Shappell; George V. Thomas; Richard L. Roberts; Ron Herbert; Michael M. Ittmann; Mark A. Rubin; Peter A. Humphrey; John P. Sundberg; Nora Rozengurt; Roberto Barrios; Jerrold M. Ward; and Robert D. Cardiff

2004-03-15T23:59:59.000Z

184

Social Scaling: From scale-free to stretched exponential models for scalar stress, hierarchy, levels and units in human and technological networks and evolution1  

E-Print Network [OSTI]

at different levels to reduce information and energy load by substituting relationships among leaders. These characteristics of scale-free modeling have been successful in biology, and social scaling may well follow from individuals to groups as a way of renormalizing information load with respect to human attentional

White, Douglas R.

185

Epicutaneous Model of Community-Acquired Staphylococcus aureus Skin Infections  

Science Journals Connector (OSTI)

...is an increasingly costly and dangerous public health threat in the United States...Comparison of community- and health care-associated methicillin-resistant...spider bite. Fam. Community Health 32 :76-84. 17. Francis JS...

Ranjani Prabhakara; Oded Foreman; Roberto De Pascalis; Gloria M. Lee; Roger D. Plaut; Stanley Y. Kim; Scott Stibitz; Karen L. Elkins; Tod J. Merkel

2013-02-04T23:59:59.000Z

186

Nuclear skin emergence in Skyrme deformed Hartree-Fock calculations  

E-Print Network [OSTI]

A study of the charge and matter densities and the corresponding rms radii for even-even isotopes of Ni, Kr, and Sn has been performed in the framework of deformed self-consistent mean field Skyrme HF+BCS method. The resulting charge radii and neutron skin thicknesses of these nuclei are compared with available experimental data, as well as with other theoretical predictions. The formation of a neutron skin, which manifests itself in an excess of neutrons at distances greater than the radius of the proton distribution, is analyzed in terms of various definitions. Formation of a proton skin is shown to be unlikely. The effects of deformation on the neutron skins in even-even deformed nuclei far from the stability line are discussed.

Sarriguren, P; de Guerra, E Moya; Antonov, A N

2007-01-01T23:59:59.000Z

187

Neutron skin of nuclei near the neutron drip line  

Science Journals Connector (OSTI)

Performing Skyrme-type deformed Hartree-Fock calculations, the possible presence of neutron skin in nuclei towards neutron drip line is studied. The thickness of the neutron skin is found to be nearly constant in all directions if it is measured perpendicular to the surface, and in a given nucleus the number of neutrons being inside of the neutron skin is almost independent of the deformation (namely, spherical shape or normal deformation or superdeformation). In the region of medium-heavy nuclei our calculation shows the presence of a series of neutron-rich nuclei, in which a neutron skin is present and yet the neutron one-particle spectra are far from those in a harmonic oscillator (plus spin-orbit) potential.

I. Hamamoto and X. Z. Zhang

1995-11-01T23:59:59.000Z

188

Mpemba paradox: Hydrogen bond memory and water-skin supersolidity  

E-Print Network [OSTI]

Numerical reproduction of measurements, experimental evidence for skin super-solidity and hydrogen-bond memory clarified that Mpemba paradox integrates the heat emission-conduction-dissipation dynamics in the source-path-drain cycle system.

Chang Q Sun

2015-01-05T23:59:59.000Z

189

Carmichael's Concise Review Microscopy is Only Skin Deep  

E-Print Network [OSTI]

Carmichael's Concise Review Microscopy is Only Skin Deep Stephen W. Carmichael Mayo Clinic. Coming Events 2011 EMAS 2011 May 15­19, 2011 Angers, France www.emas-web.net IUMAS-V May 22­27, 2011

Heller, Eric

190

Evidence for a role of calmodulin in serum stimulation of Na+ influx in human fibroblasts  

Science Journals Connector (OSTI)

...modulin-dependent phosphodiesterase activity (16). Other workers have shown that these agents also inhibit other cal...from human fore- skin were obtained from James Regan (Oak Ridge National Lab- oratory). The cells were cultured in...

N E Owen; M L Villereal

1982-01-01T23:59:59.000Z

191

Fluorescent silica colloids for study and visualization of skin care products  

E-Print Network [OSTI]

due to long exposures to cold and dry air (7). Different skin care products are used to hy- drate dryFluorescent silica colloids for study and visualization of skin care products Swaminathan Iyer: The efficacy of skin care products depends on the time and dynamics of their absorbance by the skin, and its

Sokolov, Igor

192

Be-CoDiS: An epidemiological model to predict the risk of human diseases spread worldwide. Application to the 2014 Ebola Virus Disease epidemic  

E-Print Network [OSTI]

Ebola virus disease is a lethal human and primate disease that currently requires a particular attention from the national and international health authorities due to important outbreaks concurring in some Western African countries and possible spread to other continents, which has already occurred in the USA and Spain. Regarding the emergency of this situation, there is a need of development of decision tools to help the authorities to focus their efforts in important factors that can help to eradicate Ebola. Mathematical modeling and, more precisely, epidemiological modeling can help to predict the possible evolution of the Ebola outbreaks and to give some recommendations in the region to be prioritized for surveillance. In this work, we present a first formulation of a new spatial-temporal epidemiological model, called Be-CoDiS (Between-COuntries Disease Spread), based on the combination of a deterministic Individual-Based model (modelling the interaction between countries, considered as individual) for be...

Benjamin, Ivorra; Diène, Ngom

2014-01-01T23:59:59.000Z

193

A Novel mouse model of enhanced proteostasis: Full-length human heat shock factor 1 transgenic mice  

SciTech Connect (OSTI)

Research highlights: {yields} Development of mouse overexpressing native human HSF1 in all tissues including CNS. {yields} HSF1 overexpression enhances heat shock response at whole-animal and cellular level. {yields} HSF1 overexpression protects from polyglutamine toxicity and favors aggresomes. {yields} HSF1 overexpression enhances proteostasis at the whole-animal and cellular level. -- Abstract: The heat shock response (HSR) is controlled by the master transcriptional regulator heat shock factor 1 (HSF1). HSF1 maintains proteostasis and resistance to stress through production of heat shock proteins (HSPs). No transgenic model exists that overexpresses HSF1 in tissues of the central nervous system (CNS). We generated a transgenic mouse overexpressing full-length non-mutant HSF1 and observed a 2-4-fold increase in HSF1 mRNA and protein expression in all tissues studied of HSF1 transgenic (HSF1{sup +/0}) mice compared to wild type (WT) littermates, including several regions of the CNS. Basal expression of HSP70 and 90 showed only mild tissue-specific changes; however, in response to forced exercise, the skeletal muscle HSR was more elevated in HSF1{sup +/0} mice compared to WT littermates and in fibroblasts following heat shock, as indicated by levels of inducible HSP70 mRNA and protein. HSF1{sup +/0} cells elicited a significantly more robust HSR in response to expression of the 82 repeat polyglutamine-YFP fusion construct (Q82YFP) and maintained proteasome-dependent processing of Q82YFP compared to WT fibroblasts. Overexpression of HSF1 was associated with fewer, but larger Q82YFP aggregates resembling aggresomes in HSF1{sup +/0} cells, and increased viability. Therefore, our data demonstrate that tissues and cells from mice overexpressing full-length non-mutant HSF1 exhibit enhanced proteostasis.

Pierce, Anson, E-mail: piercea2@uthscsa.edu [Department of Cellular and Structural Biology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78229 (United States) [Department of Cellular and Structural Biology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78229 (United States); Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78229 (United States); The Department of Veteran's Affairs, South Texas Veterans Health Care System, San Antonio, Texas, 78284 (United States); Wei, Rochelle; Halade, Dipti [Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78229 (United States)] [Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78229 (United States); Yoo, Si-Eun [Department of Cellular and Structural Biology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78229 (United States) [Department of Cellular and Structural Biology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78229 (United States); Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78229 (United States); Ran, Qitao; Richardson, Arlan [Department of Cellular and Structural Biology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78229 (United States) [Department of Cellular and Structural Biology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78229 (United States); Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78229 (United States); The Department of Veteran's Affairs, South Texas Veterans Health Care System, San Antonio, Texas, 78284 (United States)

2010-11-05T23:59:59.000Z

194

Patch-occupancy models indicate human activity as major determinant of forest elephant Loxodonta cyclotis seasonal distribution in an industrial corridor in Gabon  

Science Journals Connector (OSTI)

The importance of human activity and ecological features in influencing African forest elephant ranging behaviour was investigated in the Rabi–Ndogo corridor of the Gamba Complex of Protected Areas in southwest Gabon. Locations in a wide geographical area with a range of environmental variables were selected for patch-occupancy surveys using elephant dung to assess seasonal presence and absence of elephants. Patch-occupancy procedures allowed for covariate modelling evaluating hypotheses for both occupancy in relation to human activity and ecological features, and detection probability in relation to vegetation density. The best fitting models for old and fresh dung data sets indicate that (1) detection probability for elephant dung is negatively related to the relative density of the vegetation, and (2) human activity, such as presence and infrastructure, are more closely associated with elephant distribution patterns than are ecological features, such as the presence of wetlands and preferred fresh fruit. Our findings emphasize the sensitivity of elephants to human disturbance, in this case infrastructure development associated with gas and oil production. Patch-occupancy methodology offers a viable alternative to current transect protocols for monitoring programs with multiple covariates.

Ralph Buij; William J. McShea; Patrick Campbell; Michelle E. Lee; Francisco Dallmeier; Sylvain Guimondou; Loïc Mackaga; Nicaise Guisseougou; Serge Mboumba; James E. Hines; James D. Nichols; Alfonso Alonso

2007-01-01T23:59:59.000Z

195

Abstract 2043: Modeling the differential responses of cancer stem cells (CSCs) as heterogeneous versus homogenous populations in human cancers  

Science Journals Connector (OSTI)

...Biomodels, LLC, Watertown, MA. Emerging data suggests that many human cancers including breast, brain, lung, colon, pancreatic and head and neck cancer are maintained by a subpopulation of self-renewing cells characterized as cancer stem...

Maria L. Mancini

2014-10-01T23:59:59.000Z

196

First-principles modeling of fluid and solute exchange in the human during normal and hemodialysis conditions  

Science Journals Connector (OSTI)

A first-principles computer model of fluid and solute exchange under both physiological and hemodialysis condition is presented. The whole system has been modeled and simulated under the MODELICA integrated environment, which uses a hierarchical modeling ... Keywords: First-principles modeling, Fluid and solute balance, Hemodialysis, Hierarchical modeling, MODELICA simulation language

J. Fernandez de Canete; P. Del Saz Huang

2010-09-01T23:59:59.000Z

197

Viability of adult rat skin following 13 Mev proton irradiation  

E-Print Network [OSTI]

then removed from suspension by centrifugation and washed twice in Smith's chick heart growth media. 33 All cells removed from the biopsy by this enzyme dissection were placed in culture to check viability. Two Rose chambers con- taining the first scraping... Dissipation . Diagram ? Proton Energy Dissipation 17 17 Cell Suspension Filter Tube. Exploded View of Rose Chamber 24 Rat 822, Gross Appearance 37 SB. Rat 822, Skin Section. 38 Rat 771, Gross Appearance 37 Rat 771, Skin Section. 38 7A. 7B. Rat 835...

Caraway, Bobby Lamar

1966-01-01T23:59:59.000Z

198

The use of polarized light for skin cancer detecton  

E-Print Network [OSTI]

cancer will bc diagnosed in the United States each year, making it the 7'" most common form of cancer in the United States. In addition, because of current trends in sun exposure and artificial tanning, the rate of skin This Thesis follows 1he style.... 3 million new cases of skin cancer are diagnosed in the United States each year In 2000 alone, there were about 47, 700 new cases of melanoma and 7, 700 deaths attributed to the disease' . Because of current trends in sun exposure and artificial...

DeLaughter, Aimee Hill

2012-06-07T23:59:59.000Z

199

Sulforaphane induces phase II detoxication enzymes in mouse skin and prevents mutagenesis induced by a mustard gas analog  

SciTech Connect (OSTI)

Mustard gas, used in chemical warfare since 1917, is a mutagenic and carcinogenic agent that produces severe dermal lesions for which there are no effective therapeutics; it is currently seen as a potential terrorist threat to civilian populations. Sulforaphane, found in cruciferous vegetables, is known to induce enzymes that detoxify compounds such as the sulfur mustards that react through electrophilic intermediates. Here, we observe that a single topical treatment with sulforaphane induces mouse epidermal levels of the regulatory subunit of glutamate-cysteine ligase, the rate-limiting enzyme in glutathione biosynthesis, and also increases epidermal levels of reduced glutathione. Furthermore, a glutathione S-transferase, GSTA4, is also induced in mouse skin by sulforaphane. In an in vivo model in which mice are given a single mutagenic application of the sulfur mustard analog 2-(chloroethyl) ethyl sulfide (CEES), we now show that therapeutic treatment with sulforaphane abolishes the CEES-induced increase in mutation frequency in the skin, measured four days after exposure. Sulforaphane, a natural product currently in clinical trials, shows promise as an effective therapeutic against mustard gas. -- Highlights: ? Sulforaphane induces increased levels of glutathione in mouse skin. ? Sulforaphane induces increased levels of GSTA4 in mouse skin. ? Sulforaphane, applied after CEES-treatment, completely abolishes CEES-mutagenesis. ? The therapeutic effect may suggest a long biological half-life for CEES in vivo.

Abel, E.L. [Department of Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Science Park, Smithville, TX 78957 (United States)] [Department of Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Science Park, Smithville, TX 78957 (United States); Boulware, S. [Division of Pharmacy and Toxicology, College of Pharmacy, The University of Texas at Austin, Dell Pediatric Research Institute, 1400 Barbara Jordan Blvd., Austin, TX 78723 (United States)] [Division of Pharmacy and Toxicology, College of Pharmacy, The University of Texas at Austin, Dell Pediatric Research Institute, 1400 Barbara Jordan Blvd., Austin, TX 78723 (United States); Fields, T.; McIvor, E.; Powell, K.L. [Department of Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Science Park, Smithville, TX 78957 (United States)] [Department of Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Science Park, Smithville, TX 78957 (United States); DiGiovanni, J.; Vasquez, K.M. [Division of Pharmacy and Toxicology, College of Pharmacy, The University of Texas at Austin, Dell Pediatric Research Institute, 1400 Barbara Jordan Blvd., Austin, TX 78723 (United States)] [Division of Pharmacy and Toxicology, College of Pharmacy, The University of Texas at Austin, Dell Pediatric Research Institute, 1400 Barbara Jordan Blvd., Austin, TX 78723 (United States); MacLeod, M.C., E-mail: mcmacleod@mdanderson.org [Department of Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Science Park, Smithville, TX 78957 (United States)

2013-02-01T23:59:59.000Z

200

Subclonal variation and skin russeting in potato, (Solanum tuberosum L.)  

E-Print Network [OSTI]

of subclonal selection for putative russet skin mutations of 'Century Russet' was conducted in Texas and Colorado to improve the russeting character in 'Century Russet'. RAPD analysis of a segregating F I family derived from a russet x white cross and of three...

Oehlke, Leslie Lashaun

1997-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "human skin model" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


201

SKIN CANCER INSTITUTE THE CANCER INSTITUTES AT NORTHWESTERN MEDICINE  

E-Print Network [OSTI]

SKIN CANCER INSTITUTE THE CANCER INSTITUTES AT NORTHWESTERN MEDICINE Melanoma The Most Lethal Form advances in nanotechnology to increase our understanding of melanoma and to develop new tools into controllable cells or target them for destruction. Investigators also are using nanotechnology to understand

Engman, David M.

202

RAZEGHI et al.: SKIN LESION IMAGE RECOGNITION 1 Skin Lesion Image Recognition with  

E-Print Network [OSTI]

a recognition rate of 20%, whilst with human in the loop the performance can be boosted to over 96%. We also diagnosis. Unlike the majority of publications in the area of computer vision for dermatology appli- cations of related work is an image analysis system presented in [1] that differentiates early melanoma from benign

Aickelin, Uwe

203

Design of a thermal diffusion sensor for noninvasive assessment of skin surface perfusion and endothelial dysfunction  

E-Print Network [OSTI]

The skin microcirculation performs a range of vital functions, such as maintaining nutritional perfusion to the tissues and overall thermoregulation. Not only does impairment to the skin blood supply lead to tissue necrosis ...

Li, Vivian V. (Vivian Victoria)

2008-01-01T23:59:59.000Z

204

E-Print Network 3.0 - arsenic-induced skin lesions Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

technique Summary: pigmented skin lesions M.MONCRIEFF,* S.COTTON, E.CLARIDGE AND P.HALL* *Department of Plastic... technique for imaging pigmented skin lesions and for...

205

Guest editorial: Special issue on human computing  

E-Print Network [OSTI]

The seven articles in this special issue focus on human computing. Most focus on two challenging issues in human computing, namely, machine analysis of human behavior in group interactions and context-sensitive modeling.

Pantic, Maja

206

E-Print Network 3.0 - aggressive skin malignancy Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Stanford University Collection: Biology and Medicine 3 Publication Schedule Advertising Summary: aggressive form of skin cancer -- malignant melanoma -- stress, including...

207

Skin cancer is the most com-mon form of cancer in the United  

E-Print Network [OSTI]

Skin cancer is the most com- mon form of cancer in the United States. Excessive and unprotected exposure to the sun's ultraviolet radiation (UV light) is the primary risk factor for skin cancer. Howev- er, skin cancer is one of the most preventable types of cancer! The damaging and cumulative effects

208

Skin Cancer: A Young Person's Disease By Lauren Duffy (B.S. Communication, Journalism '14)  

E-Print Network [OSTI]

Skin Cancer: A Young Person's Disease By Lauren Duffy (B.S. Communication, Journalism '14 is that this behavior is extremely unhealthy and risky for their bodies, specifically their skin. Skin cancer is the most common form of cancer found in young adults and second most common cancer found in adolescents

Massachusetts at Amherst, University of

209

Human Ecology Human ecology Research  

E-Print Network [OSTI]

Human Ecology Impact of Human ecology Research Bonus Issue FROM SCHOLARSHIP TO POLICY MAKING OF HUMAN ECOLOGY APRIL 2005/VOLUME 33, NUMBER 1 #12;Human Ecology Volume 33, Number 1 April 2005 The New York State College of Human Ecology at Cornell University Lisa Staiano-Coico, Ph.D. Rebecca Q

Wang, Z. Jane

210

Cell-Free Transmission of Human Adenovirus by Passive Mass Transfer in Cell Culture Simulated in a Computer Model  

Science Journals Connector (OSTI)

...averaged them from 15 in silico simulations (Fig. 8E). As expected...as shown previously for simulations of biological diffusion processes...transcomplementation. The modeling platform established here...effects, which will allow the modeling of cell-cell spreading...

Artur Yakimovich; Heidi Gumpert; Christoph J. Burckhardt; Verena A. Lütschg; Andreas Jurgeit; Ivo F. Sbalzarini; Urs F. Greber

2012-07-11T23:59:59.000Z

211

Elimination of influence of neutron-skin size difference of initial colliding nuclei in Pb+Pb collisions  

E-Print Network [OSTI]

Within an isospin- and momentum-dependent transport model using as an input nucleon density profiles from Hartree-Fock calculations based on a modified Skyrme-like (MSL) model, we study how to eliminate the influence of neutron-skin size difference of initial colliding nuclei in probing the nuclear symmetry energy. Within the current experimental uncertainty range of neutron-skin size of $^{208}$Pb, the Pb+Pb collisions are performed in semicentral and peripheral collisions with impact parameters of 5 and 9fm and at beam energies from 50 MeV/nucleon to 1000 MeV/nucleon, respectively. It is shown that combination of neutron and proton collective flows, i.e., neutron-proton differential elliptic flow, neutron-proton elliptic flow difference, neutron-proton differential transverse flow and neutron-proton transverse flow difference, can effectively eliminate the effects of neutron-skin size difference and thus can be as useful sensitive observables in probing nuclear matter symmetry energy in heavy-ion collisions...

Wei, Gao-Feng

2015-01-01T23:59:59.000Z

212

Low Dose Radiation Research Program: Adaptive Response of Mouse Skin  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Adaptive Response of Mouse Skin Epithelial Cells to Low Dose Adaptive Response of Mouse Skin Epithelial Cells to Low Dose Ionizing Radiation: Induction of NF-κB, MnSOD, 14-3-3ζ and Cyclin B1 Authors: Jian Jian Li, Kazi M. Ahmed, Ming Fan, Shaozhong Dong, Douglas R. Spitz, and Cheng-Rong Yu Institutions: Division of Molecular Radiobiology, Purdue University School of Health Sciences, West Lafayette, Indiana; Free Radical and Radiation Biology Program, Department of Radiation Oncology, Holden Comprehensive Cancer Center, The University of Iowa, Iowa City, Iowa; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland Gene expression profiles demonstrate that a group of key stress-responsive genes are associated with radiation exposure and may contribute to cellular

213

Anomalous skin effects in a weakly magnetized degenerate electron plasma  

SciTech Connect (OSTI)

Fully relativistic analysis of anomalous skin effects for parallel propagating waves in a weakly magnetized degenerate electron plasma is presented and a graphical comparison is made with the results obtained using relativistic Maxwellian distribution function [G. Abbas, M. F. Bashir, and G. Murtaza, Phys. Plasmas 18, 102115 (2011)]. It is found that the penetration depth for R- and L-waves for degenerate case is qualitatively small in comparison with the Maxwellian plasma case. The quantitative reduction due to weak magnetic field in the skin depth in R-wave for degenerate plasma is large as compared to the non-degenerate one. By ignoring the ambient magnetic field, previous results for degenerate field free case are salvaged [A. F. Alexandrov, A. S. Bogdankevich, and A. A. Rukhadze, Principles of Plasma Electrodynamics (Springer-Verlag, Berlin/Heidelberg, 1984), p. 90].

Abbas, G., E-mail: gohar.abbas@gcu.edu.pk; Sarfraz, M. [Department of Physics, GC University Lahore, Katchery Road, Lahore 54000 (Pakistan); Shah, H. A. [Forman Christian College University, Farozpur Road, Lahore 54600 (Pakistan)

2014-09-15T23:59:59.000Z

214

Human behaviour and ecosystem services in sustainable farming landscapes : an agent-based model of socio-ecological systems   

E-Print Network [OSTI]

on agents’ interactions at smaller scale. This approach is better suited to understanding and modelling complex socio-ecological systems, which emerge from individual actions, and therefore for developing tools which improve policy effectiveness. In recent...

Guillem, Eléonore E.

2012-11-29T23:59:59.000Z

215

Radiation effects on humans  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Radiation effects on humans Radiation effects on humans Name: Joe Kemna Location: N/A Country: N/A Date: N/A Question: I am trying to find information on radiation. I need the effects on humans, the damage it causes to the environment, and any extra information you might have on the subject. Thank you for your time. Replies: Your library should be a good place to start, but first you need to narrow your question a bit. "Radiation" means radio waves, heat, light (including the ultraviolet light that causes suntan and sunburn), and what's called "ionizing radiation." By far the major source of the first three is the Sun, while the last I believe comes principally from cosmic rays and various naturally radioactive elements like uranium and radon. The most significant manmade sources of exposure would --- I think --- be household wiring and appliances (radio), engines and heating devices (heat), lamps (light), and X-ray machines, flying at high altitude in airplanes, and living in well-insulated homes built over radon sources (ionizing radiation). Heat, light and ionizing radiation play vital roles in the ecology of the Earth. Radio, light (in particular "tanning" ultraviolet), and ionizing radiation have all been widely assumed at different times to be particularly good or particularly bad for human health. Some recent issues of public concern have been the effect of radio waves from electric transmission lines, the effect on skin cancer incidence from tanning and sunburns, the depletion of the ultraviolet-light-produced ozone in the upper atmosphere by chlorofluorocarbons (CFCs), "global warming" from the increased absorption of heat radiation from the surface by atmospheric carbon dioxide and methane, and the effect of a long exposure to low levels of ionizing radiation as for example the people of Eastern Europe are experiencing from the Chernobyl nuclear power plant accident.

216

Safety, Pharmacokinetic, and Efficacy Studies of Oral DB868 in a First Stage Vervet Monkey Model of Human African Trypanosomiasis  

E-Print Network [OSTI]

-pyridyl]furan (DB868; CPD-007-10), in the vervet monkey model of first stage HAT. DB868 was well tolerated at a dose up to 30 mg/kg/day for 10 days, a cumulative dose of 300 mg/kg. Mean plasma levels of biomarkers indicative of liver injury (alanine...

Thutia, John K.; Wolf, Kristina K.; Murilla, Grace A.; Liu, Qiang; Mutuku, James N.; Chen, Yao; Bridges, Arlene S.; Mdachi, Raymond E.; Ismail, Mohamed A.; Ching, Shelley; Boykin, David W.; Hall, James E.; Tidwell, Richard R.; Paine, Mary F.; Burn, Reto; Wang, Michael Z.

2013-06-06T23:59:59.000Z

217

The Augmentation of Melanocytic Nevi in Guinea Pigs by Solar-simulated Light: An Animal Model for Human Melanocytic Nevi  

Science Journals Connector (OSTI)

...Melanocytic Nevi in Guinea Pigs by Solar-simulated Light: An Animal...followed by prolonged exposure to solar-simulated light. The specific...animal model where exposure to solar-simu lated light would induce...from Charles River (Quebec, Canada) and maintained in standard...

Scott Menzies; Mamdouh Khalil; Kerry Crotty; and Antonio Bonin

1998-12-01T23:59:59.000Z

218

UV Radiation Inhibits 15-Hydroxyprostaglandin Dehydrogenase Levels in Human Skin: Evidence of Transcriptional Suppression  

Science Journals Connector (OSTI)

...one-carbon metabolism that involves a constellation of genes including methylenetetrahydrofolate...48-50, 50-53, 53 years), and energy intake (902, 902-1147, 1147-1399...on the other hand, participate in energy production and are not directly involved...

Benjamin L. Judson; Akira Miyaki; Vikram D. Kekatpure; Baoheng Du; Patricia Gilleaudeau; Mary Sullivan-Whalen; Arash Mohebati; Sudhir Nair; Jay O. Boyle; Richard D. Granstein; Kotha Subbaramaiah; James G. Krueger; and Andrew J. Dannenberg

2010-09-01T23:59:59.000Z

219

Targeting Ornithine Decarboxylase for the Prevention of Nonmelanoma Skin Cancer in Humans  

Science Journals Connector (OSTI)

...incidence between 1977_1978 and 1998-1999 in Northcentral New Mexico. Cancer Epidemiol Biomarkers Prev 2003;12:1105-8. 3...732-6. 8 Thompson SC , Jolley D, Marks R. Reduction of solar keratoses by regular sunscreen use. N Engl J Med 1993;329...

Craig A. Elmets and Mohammad Athar

2010-01-01T23:59:59.000Z

220

Ultraviolet B-induced DNA Damage in Human Skin and Its Modulation by a Sunscreen  

Science Journals Connector (OSTI)

...Abstract The UVB component of solar radiation is a risk factor for...defined as the ratio of the energy required to produce a MED...sunscreen compared with the energy required to produce the same...able to reduce many effects of solar radiation, it is unclear how...

Vladimir J. Bykov; Jan A. Marcusson; and Kari Hemminki

1998-07-15T23:59:59.000Z

Note: This page contains sample records for the topic "human skin model" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


221

High-resolution imaging of microvasculature in human skin in-vivo with optical coherence tomography  

E-Print Network [OSTI]

using swept-source optical coherence tomography,” Opt. Lett.J. G. Fujimoto, “Optical coherence tomography,” Science 254(volumes using optical coherence tomography,” Opt. Lett. 22(

Liu, Gangjun; Jia, Wangcun; Sun, Victor; Choi, Bernard; Chen, Zhongping

2012-01-01T23:59:59.000Z

222

Varicella-Zoster Virus Infection Induces Autophagy in both Cultured Cells and Human Skin Vesicles  

Science Journals Connector (OSTI)

...Devenish, F. Di Sano, J. F. Dice, M. Difiglia, S. Dinesh-Kumar, C. W. Distelhorst, M. Djavaheri-Mergny, F...Czymmek, Z. Talloczy, B. Levine, and S. P. Dinesh-Kumar. 2005. Autophagy regulates programmed cell death...

Marie-Noëlle Takahashi; Wallen Jackson; Donna T. Laird; Timothy D. Culp; Charles Grose; John I. Haynes II; Luca Benetti

2009-03-18T23:59:59.000Z

223

Human skin keratinocytes modified by a Friend-derived retroviral vector: A functional approach  

E-Print Network [OSTI]

15 %). Colony Forming Efficiency (CFE) assays were done withand negative controls. There was no difference in CFE (%CFE= 10.74±6.53 negative control vs % CFE= 9.22±5.45 with

Arango, M; Chamorro, C; Cohen-Haguenauer, O; Rojas, M; Restrepo, LM

2005-01-01T23:59:59.000Z

224

Steady-state directional diffuse reflectance and fluorescence of human skin  

E-Print Network [OSTI]

or tissue of interest to excitation light (typically UV) and measuring the flu- orescence emission spectrum or diffuse according to whether a laser or a diffuse light source is used. These measurements can be carried by a high- speed detection system. The advantage of time- resolved over steady-state measurements

Pilon, Laurent

225

Apparatus for testing skin samples or the like  

DOE Patents [OSTI]

An apparatus for testing the permeability of living skin samples has a flat base with a plurality of sample-holding cavities formed in its upper surface, the samples being placed in counterbores in the cavities with the epidermis uppermost. O-rings of Teflon washers are respectively placed on the samples and a flat cover is connected to the base to press the rings against the upper surfaces of the samples. Media to maintain tissue viability and recovery of metabolites is introduced into the lower portion of the sample-holding cavities through passages in the base. Test materials are introduced through holes in the cover plate after assembly of the chamber.

Holland, J.M.

1982-08-31T23:59:59.000Z

226

Thiothymidine plus low-dose UVA kills hyperproliferative human skin cells independently of their human papilloma virus status  

Science Journals Connector (OSTI)

...further (1-3). Solar radiation is the major...development of the basal cell carcinomas and squamous cell carcinomas (SCC...fraction of incident solar UVA (wavelengths...1:1,000) from Cell Signaling Technology, Inc. Secondary...

Olivier Reelfs; Yao-Zhong Xu; Andrew Massey; Peter Karran; and Alan Storey

2007-09-01T23:59:59.000Z

227

Antiviral activity of 2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl-5-iodocytosine against human cytomegalovirus in human skin fibroblasts.  

Science Journals Connector (OSTI)

...readily reversed with 10-fold excess thymidine, whereby the 50...readily reversed with 10-fold excess of deoxycytidine, whereby...thymidine (dThd), NaF, lithium chloride, creatine phosphate...or an equimolar or 10-fold excess concentration ofdCyd or dThd...

J M Colacino; C Lopez

1985-08-01T23:59:59.000Z

228

Physiological observations validate finite element models for estimating subject-specific electric field distributions induced by transcranial magnetic stimulation of the human motor cortex  

Science Journals Connector (OSTI)

Abstract Recent evidence indicates subject-specific gyral folding patterns and white matter anisotropy uniquely shape electric fields generated by TMS. Current methods for predicting the brain regions influenced by TMS involve projecting the TMS coil position or center of gravity onto realistic head models derived from structural and functional imaging data. Similarly, spherical models have been used to estimate electric field distributions generated by TMS pulses delivered from a particular coil location and position. In the present paper we inspect differences between electric field computations estimated using the finite element method (FEM) and projection-based approaches described above. We then more specifically examined an approach for estimating cortical excitation volumes based on individualistic FEM simulations of electric fields. We evaluated this approach by performing neurophysiological recordings during MR-navigated motormapping experiments. We recorded motor evoked potentials (MEPs) in response to single pulse TMS using two different coil orientations (45° and 90° to midline) at 25 different locations (5 × 5 grid, 1 cm spacing) centered on the hotspot of the right first dorsal interosseous (FDI) muscle in left motor cortex. We observed that motor excitability maps varied within and between subjects as a function of TMS coil position and orientation. For each coil position and orientation tested, simulations of the TMS-induced electric field were computed using individualistic FEM models and compared to MEP amplitudes obtained during our motormapping experiments. We found FEM simulations of electric field strength, which take into account subject-specific gyral geometry and tissue conductivity anisotropy, significantly correlated with physiologically observed MEP amplitudes (rmax = 0.91, p = 1.8 × 10-5 rmean = 0.81, p = 0.01). These observations validate the implementation of individualistic FEM models to account for variations in gyral folding patterns and tissue conductivity anisotropy, which should help improve the targeting accuracy of TMS in the mapping or modulation of human brain circuits.

Alexander Opitz; Wynn Legon; Abby Rowlands; Warren K. Bickel; Walter Paulus; William J. Tyler

2013-01-01T23:59:59.000Z

229

Amelioration of motor/sensory dysfunction and spasticity in a rat model of acute lumbar spinal cord injury by human neural stem cell transplantation  

Science Journals Connector (OSTI)

Human foetal stem cell grafts improve both motor and sensory functions in rats suffering from a spinal cord injury, demonstrating potential for cell replacement therapy in human spinal cord injuries.

Sebastiaan van Gorp; Marjolein Leerink; Osamu Kakinohana; Oleksandr Platoshyn; Camila Santucci; Jan Galik; Elbert A Joosten; Marian Hruska-Plochan; Danielle Goldberg; Silvia Marsala; Karl Johe; Joseph D Ciacci; Martin Marsala

2013-05-28T23:59:59.000Z

230

E-Print Network 3.0 - artificial skin construct Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Source: Controlled Fusion Atomic Data Center (CFADC) Collection: Plasma Physics and Fusion 17 Conjunctive Types and SKInT Jean GoubaultLarrecq ? Summary: Conjunctive Types...

231

E-Print Network 3.0 - atopic dermatitis skin Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Tacrolimus binds to an intracellular protein called the FK- 506 binding protein... the penetration rate through hairless mouse skin. Tacrolimus-loaded NLCs were found to have an...

232

E-Print Network 3.0 - arsenic-related skin lesions Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

7 | July 2002 729 Family Correlations of Arsenic Methylation Patterns in Children and Parents Summary: various health effects, including can- cers of the bladder, skin, and...

233

Atmospheric-pressure dielectric barrier discharge (DBD) in air : plasma characterisation for skin therapy.  

E-Print Network [OSTI]

??A pulsed atmospheric-pressure dielectric barrier discharge (DBD) device operating in air is investigated for medical applications such as for skin disinfection and promotion of wound… (more)

Rajasekaran, Priyadarshini

2011-01-01T23:59:59.000Z

234

Predictors of occupational skin disease among seafood processing workers in the Western Cape.  

E-Print Network [OSTI]

??Includes abstract. Occupational skin disease is common in seafood processing workers. While previous studies have reported an increased prevalence of symptoms (as high as 50%)… (more)

Burdzik, Amy.

2012-01-01T23:59:59.000Z

235

E-Print Network 3.0 - apso skin friction Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

in Three-Dimensional Flows Summary: Abstract Recent improvements in three techniques for measuring skin friction in two- and three- dimensional... that the oil- film...

236

E-Print Network 3.0 - acute skin toxicity Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Summary: that bind to transthyretin, a thyroxine binding protein. 12;Toxicity of Dioxins Acute Toxicity Varies... skin Reproductive effects of not seen with glycols...

237

E-Print Network 3.0 - amphibian skin epithelium Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

ulcers & bloating are keySkin... AmphibiansInfections in Wild Amphibians D. Earl Green, DVMD. Earl Green, DVM Department of Interior... % of larvae -- Onset is sudden...

238

Simulating human behavior for national security human interactions.  

SciTech Connect (OSTI)

This 3-year research and development effort focused on what we believe is a significant technical gap in existing modeling and simulation capabilities: the representation of plausible human cognition and behaviors within a dynamic, simulated environment. Specifically, the intent of the ''Simulating Human Behavior for National Security Human Interactions'' project was to demonstrate initial simulated human modeling capability that realistically represents intra- and inter-group interaction behaviors between simulated humans and human-controlled avatars as they respond to their environment. Significant process was made towards simulating human behaviors through the development of a framework that produces realistic characteristics and movement. The simulated humans were created from models designed to be psychologically plausible by being based on robust psychological research and theory. Progress was also made towards enhancing Sandia National Laboratories existing cognitive models to support culturally plausible behaviors that are important in representing group interactions. These models were implemented in the modular, interoperable, and commercially supported Umbra{reg_sign} simulation framework.

Bernard, Michael Lewis; Hart, Dereck H.; Verzi, Stephen J.; Glickman, Matthew R.; Wolfenbarger, Paul R.; Xavier, Patrick Gordon

2007-01-01T23:59:59.000Z

239

Adeno-Associated Virus Type 2 Wild-Type and Vector-Mediated Genomic Integration Profiles of Human Diploid Fibroblasts Analyzed by Third-Generation PacBio DNA Sequencing  

Science Journals Connector (OSTI)

...with variant hot spot preferences. DNase-Seq patterns of these sites in human tissues, including liver, muscle, heart, brain, skin, and embryonic stem cells further underline variant chromatin accessibility. In summary, AAV integration is dependent...

Daniela Hüser; Andreas Gogol-Döring; Wei Chen; Regine Heilbronn

2014-07-16T23:59:59.000Z

240

HEAT TRANSFERS IN A DOUBLE SKIN ROOF VENTILATED BY NATURAL CONVECTION IN SUMMER TIME  

E-Print Network [OSTI]

1 HEAT TRANSFERS IN A DOUBLE SKIN ROOF VENTILATED BY NATURAL CONVECTION IN SUMMER TIME P. H or in tropical and arid countries. In this work, radiation, convection and conduction heat transfers-dimensional numerical simulation of the heat transfers through the double skin reveals the most important parameters

Boyer, Edmond

Note: This page contains sample records for the topic "human skin model" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


241

Asian Females in an Advertising Context: Exploring Skin Tone Tension Anjala S. Krishen  

E-Print Network [OSTI]

Asian Females in an Advertising Context: Exploring Skin Tone Tension Anjala S. Krishen Department in the completion of this research. 1 #12;Asian Females in an Advertising Context: Exploring Skin Tone Tension Abstract While the explosive literature on the portrayal of women in advertising has established

Ahmad, Sajjad

242

Bored By Non-Glowing Skin? Ultra-Flexible, Waterproof LED Implants Are What You Seek  

E-Print Network [OSTI]

Bored By Non-Glowing Skin? Ultra-Flexible, Waterproof LED Implants Are What You Seek By Alasdair Wilkins/io9 Posted 10.19.2010 at 12:15 pm LED Lights Could Be Implanted Under Skin Photo courtesy of iO9 LEDs are, on small scales, the cheapest, most reliable, and most technologically powerful light sources

Rogers, John A.

243

Caffeic Acid Directly Targets ERK1/2 to Attenuate Solar UV-Induced Skin Carcinogenesis  

Science Journals Connector (OSTI)

...operated for the U.S. Department of Energy Office of Science by the Argonne National...Lachiewicz A, Pestak C, Thomas N.Solar UV exposure and mortality from skin tumors...117-24. 6. de Gruijl FR .Skin cancer and solar UV radiation.Eur J Cancer 1999;35...

Ge Yang; Yang Fu; Margarita Malakhova; Igor Kurinov; Feng Zhu; Ke Yao; Haitao Li; Hanyong Chen; Wei Li; Do Young Lim; Yuqiao Sheng; Ann M. Bode; Ziming Dong; and Zigang Dong

2014-10-01T23:59:59.000Z

244

Automatic Skin Enhancement with Visible and Near-Infrared Image Fusion  

E-Print Network [OSTI]

Automatic Skin Enhancement with Visible and Near-Infrared Image Fusion Sabine Süsstrunk School and hemo- globin, the key components of skin color, have little absorp- tion in the near-infrared (NIR to the incident light's wavelength, we show that near-infrared images provide information that can be used

Salvaggio, Carl

245

Associations Between Drinking Water and Urinary Arsenic Levels and Skin Lesions in  

E-Print Network [OSTI]

Associations Between Drinking Water and Urinary Arsenic Levels and Skin Lesions in Bangladesh Graziano, PhD The present study examined the associations between drinking water and urinary arsenic levels currently drinking water containing concentrations of arsenic 50 g/L. The risk for skin lesions in relation

van Geen, Alexander

246

Arsenic in Drinking Water and Skin Lesions: Dose-Response Data from West Bengal, India  

E-Print Network [OSTI]

Arsenic in Drinking Water and Skin Lesions: Dose-Response Data from West Bengal, India Reina Haque the dose-re- sponse relation between low arsenic concentrations in drinking water and arsenic-induced skin peak arsenic concentration in drinking water was 325 g/liter for cases and 180 g/liter for controls

California at Berkeley, University of

247

Forensic identification using skin bacterial communities Noah Fierera,b,1  

E-Print Network [OSTI]

Forensic identification using skin bacterial communities Noah Fierera,b,1 , Christian L. Lauberb are personalized, we hypothesized that we could use the residual skin bacteria left on objects for forensic approach, this series ofstudies introducesa forensics approach that could eventually be used

Fierer, Noah

248

THE EFFECTS OF HIV INFECTION ON THE EXPRESSION OF THE DRUG EFFLUX PROTEINS P-GLYCOPROTEIN AND BREAST CANCER RESISTANCE PROTEIN IN A HUMAN INTESTINE MODEL  

E-Print Network [OSTI]

Background: Emerging evidence suggests poor antiretroviral penetration within human gastrointestinal (GI) tissues may contribute to HIV persistence within reservoirs despite effective therapy. We hypothesize that HIV ...

Ellis, Kelstan Lynch

2012-08-31T23:59:59.000Z

249

Humans and models: converging ‘truths’  

E-Print Network [OSTI]

and accidental deaths among Cherokee Indians: a naturaland accidental deaths among Cherokee Indians in rural NorthIn our analysis of the Cherokee response to acute and large

Bruckner, Tim A; Margerison-Zilko, Claire

2011-01-01T23:59:59.000Z

250

Deep Beams and Slabs The purpose of skin reinforcement in a deep beam is to limit the  

E-Print Network [OSTI]

Deep Beams and Slabs Deep Beams The purpose of skin reinforcement in a deep beam is to limit require different amounts of skin reinforcement. The purpose of our experiment is to compare beams designed with the different amounts of skin reinforcement required by these codes. 3 deep beams following

Barthelat, Francois

251

Combining visible and near-infrared images for realistic skin Clement Fredembach, Nathalie Barbuscia and Sabine Susstrunk  

E-Print Network [OSTI]

Combining visible and near-infrared images for realistic skin smoothing Cl´ement Fredembach components of skin colour, have little absorption in the near-infrared part of the spectrum propose that near-infrared images provide information that can be used to automatically smooth skin tones

Salvaggio, Carl

252

CAMB 630 Topics in Human Genetics and Disease Course Directors  

E-Print Network [OSTI]

on the foundations of the Human Genome Project and parallel efforts in model organisms, research in human genetics in Human Genetics and Disease: I. Genome architecture and instability (Spinner) Chromosome specific variation II. Human genomic variation and disease (Devoto) History and substructure of the human population

Plotkin, Joshua B.

253

Determining the density content of symmetry energy and neutron skin: an empirical approach  

E-Print Network [OSTI]

The density dependence of nuclear symmetry energy remains poorly constrained. Starting from precise empirical values of the nuclear volume and surface symmetry energy coefficients and the nuclear saturation density, we show how in the ambit of microscopic calculations with different energy density functionals, the value of the symmetry energy slope parameter $L$ alongwith that for neutron skin can be put in tighter bounds. The value of $L$ is found to be $L$= 64$\\pm $5 MeV. For $^{208}$Pb, the neutron skin thickness comes out to be 0.188 $\\pm $0.014 fm. Knowing $L$, the method can be applied to predict neutron skins of other nuclei.

Agrawal, B K; Samaddar, S K

2012-01-01T23:59:59.000Z

254

Determining the Density Content of Symmetry Energy and Neutron Skin: An Empirical Approach  

Science Journals Connector (OSTI)

The density dependence of nuclear symmetry energy remains poorly constrained. Starting from precise empirical values of the nuclear volume and surface symmetry energy coefficients and the nuclear saturation density, we show how in the ambit of microscopic calculations with different energy density functionals, the value of the symmetry energy slope parameter L along with that for neutron skin can be put in tighter bounds. The value of L is found to be L=64±5??MeV. For Pb208, the neutron skin thickness comes out to be 0.188±0.014??fm. Knowing L, the method can be applied to predict neutron skin thicknesses of other nuclei.

B. K. Agrawal; J. N. De; S. K. Samaddar

2012-12-26T23:59:59.000Z

255

Determining the density content of symmetry energy and neutron skin: an empirical approach  

E-Print Network [OSTI]

The density dependence of nuclear symmetry energy remains poorly constrained. Starting from precise empirical values of the nuclear volume and surface symmetry energy coefficients and the nuclear saturation density, we show how in the ambit of microscopic calculations with different energy density functionals, the value of the symmetry energy slope parameter $L$ alongwith that for neutron skin can be put in tighter bounds. The value of $L$ is found to be $L$= 64$\\pm $5 MeV. For $^{208}$Pb, the neutron skin thickness comes out to be 0.188 $\\pm $0.014 fm. Knowing $L$, the method can be applied to predict neutron skins of other nuclei.

B. K. Agrawal; J. N. De; S. K. Samaddar

2012-12-03T23:59:59.000Z

256

Human Nature  

Science Journals Connector (OSTI)

In the human enhancement debate, both parties advocate a partial truth. On the one hand, the bioconservatives argue that, if transhumanism is unleashed without some kind of bioethical...have (A+) is itself a prod...

Prof.; Dr. Hub Zwart

2014-08-01T23:59:59.000Z

257

Human Enhancement  

Science Journals Connector (OSTI)

Abstract Categorizing different human enhancements into personal, social, or species enhancements, as well as considering whether a particular enhancement technique generates asymmetric or network benefits, brings clarity to discussions about the ethical issues pertaining to any individual technique. The four aspects of principlism can help to assess the ethical implications of different human enhancements, revealing complexities in their aspirational claims for personally directed self-development. At a practical level, this article examines important questions about real expectations, scientific hubris, and hype.

P. Moore

2012-01-01T23:59:59.000Z

258

Ablation of p21waf1cip1 Expression Enhances the Capacity of p53-deficient Human Tumor Cells to Repair UVB-induced DNA Damage  

Science Journals Connector (OSTI)

...an early initiating event in solar UVB-induced skin cell transformation...restore much of the DNA repair capacity lost in these precancerous...p21waf1cip1 expression enhances the capacity of p53-deficient human tumor...can significantly enhance the capacity of p53-deficient human tumor...

Jean-Philippe Therrien; Martin Loignon; Régen Drouin; and Elliot A. Drobetsky

2001-05-01T23:59:59.000Z

259

Intuitive Generation of Realistic Motions for Articulated Human Characters  

E-Print Network [OSTI]

articulations, for human characters. More specifically, the goals of this research are: (1) to investigate generative statistical models and physics-based dynamic models to precisely predict how humans move and (2) to demonstrate the utility of our motion...

Min, Jianyuan

2013-01-15T23:59:59.000Z

260

Numerical investigation on photocatalytic CO2 reduction by solar energy in double-skin sheet reactor  

Science Journals Connector (OSTI)

Abstract Double-skin sheet reactor (DSSR) attracts attention in recent years due to the simple design and high mass transfer, but its application to photocatalytic CO2 reduction with immobilized catalyst is still a new trial. In this paper, the three-dimensional models describing the photocatalytic CO2 reduction in DSSR by means of solar energy were developed and numerically simulated, on the basis of the transient and continuous solar light distributions. A performance evaluation approach was proposed to guide the structural optimization of DSSR in photocatalytic CO2 reduction. The effects of operation parameters and reactor structures on CH3OH concentration were analyzed and discussed. The results show that the outlet CH3OH concentration of 2.68 × 10?4 mol m?3 in DSSR is much greater than that of 1.77 × 10?5 mol m?3 in optical fiber monolith reactor under the same conditions. It increases as both the inlet water vapor concentration ratio and day-average light flux increase, but decreases with increasing the inlet velocity, all of which are beneficial to the CH3OH productivity. The CH3OH concentration will decrease with the increase of the number of parallel-flow channels, but increase thanks to the rise in the width–height ratio and inserting flow guiding pieces, which are recommended for higher CH3OH concentration in the design of DSSR.

Tianchen Wang; Lijun Yang; Kai Yuan; Xiaoze Du; Yongping Yang

2014-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "human skin model" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


261

Infrared mapping resolves soft tissue preservation in 50 million year-old reptile skin  

Science Journals Connector (OSTI)

...serve to inhibit microbial degradation and solvent attack (hydrolysis) of the organic compounds...the fossilized skin. Calcite peaks (green box) and silicate stretch region (grey...organic peaks are distinguishable. (d) Green River fossil leaf (BHI-7032) point...

2011-01-01T23:59:59.000Z

262

Enzocide - a chemical dip for the reduction of Salmonella on chicken breast skin  

E-Print Network [OSTI]

A chemical dip, Enzocide TM, was tested to determine its effectiveness in reducing Salmonella (ST) choleraesuis subsp. typhimurium and Salmonella (SA) choleraesuis subsp. arizonae from breast skin surfaces of broilers. One hundred square...

Bianchi, Aldo

2012-06-07T23:59:59.000Z

263

A Systematic Study of Matrix Acidizing Treatments Using Skin Monitoring Method  

E-Print Network [OSTI]

The goal of this work was to evaluate matrix acidizing treatments of vertical and horizontal wells in carbonate reservoirs. Twenty field cases for acidizing treatments were analyzed by evaluating the skin factor evolution from on-site rate...

Pandya, Nimish

2012-07-16T23:59:59.000Z

264

Symmetry energy, neutron skin, and neutron star radius from chiral effective field theory interactions  

E-Print Network [OSTI]

We discuss neutron matter calculations based on chiral effective field theory interactions and their predictions for the symmetry energy, the neutron skin of 208 Pb, and for the radius of neutron stars.

K. Hebeler; A. Schwenk

2014-01-22T23:59:59.000Z

265

E-Print Network 3.0 - atopic dermatitis-like skin Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Soc. 2011, Vol. 32, No. 3 So Hee Nam et al. DOI 10.5012bkcs.2011.32.3.956 Summary: the penetration rate through hairless mouse skin. Tacrolimus-loaded NLCs were found to have an...

266

Extended Range Near-Infrared Imaging of Water and Oil in Facial Skin  

Science Journals Connector (OSTI)

Recently, near-infrared (NIR) imaging has been applied to detecting changes in skin hydration using the water OH band centered near 1460 nm. However, assigning changes in the...

Egawa, Mariko; Yanai, Motohiro; Kikuchi, Kumiko; Masuda, Yuji

2011-01-01T23:59:59.000Z

267

Skin doses to patients undergoing coronary angiography in a Greek hospital  

Science Journals Connector (OSTI)

......undergoing coronary angiography in a Greek hospital Miltiadis G. Delichas 1 Kyriakos Psarrakos...Medical Physics Department, Papageorgiou Hospital, N. Efkarpia, Thessaloniki 56403...skin during 93 CA procedures in a Greek hospital. The dose-area product (DAP) for......

Miltiadis G. Delichas; Kyriakos Psarrakos; Georgios Giannoglou; Elisabeth Molyvda-Athanasopoulou; Konstantinos Hatziioannou; Emmanouil Papanastassiou

2005-05-01T23:59:59.000Z

268

E-Print Network 3.0 - allergic skin inflammation Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Tetrakis(dimethylamino)hafnium P-6280-B Date: February 2005 Copyright 2002, 2004-2005, Praxair Technology, Inc. Page 1 of 8 Summary: dermatitis (inflammation of the skin). With...

269

Design Considerations for Double-Skin Facades in Hot and Humid Climates  

E-Print Network [OSTI]

Thermal building simulations (TRNSYS) were linked to nodal airflow network simulations (COMIS) for a ventilated double-skin facade performance calculation and overall energy consumption for office building facades. Simulation results show good...

Haase, M.; Amato, A.

2006-01-01T23:59:59.000Z

270

E-Print Network 3.0 - allergic skin test Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

test Search Powered by Explorit Topic List Advanced Search Sample search results for: allergic skin test Page: << < 1 2 3 4 5 > >> 1 Figure 1. Steps involved in immediate...

271

Design and fabrication of an optical pressure micro sensor for skin mechanics studies  

E-Print Network [OSTI]

The mechanics of skin is as central to touch as optics is to vision and acoustics is to hearing. With the advent of novel imaging technologies such as the Optical Coherence Tomography (OCT), we are now able to view structures ...

Kumar, Siddarth

2006-01-01T23:59:59.000Z

272

Percutaneous characterization of the insect repellent DEET and the sunscreen oxybenzone from topical skin application  

SciTech Connect (OSTI)

The synergistic percutaneous enhancement between insect repellent DEET and sunscreen oxybenzone has been proven in our laboratory using a series of in vitro diffusion studies. In this study, we carried out an in vivo study to characterize skin permeation profiles from topical skin application of three commercially available repellent and sunscreen preparations. The correlation between skin disposition and drug metabolism was attempted by using data collected. Both DEET and oxybenzone permeated across the skin after the application and achieved substantial systemic absorption. Combined use of DEET and oxybenzone significantly enhanced the percutaneous penetration percentages (ranging 36-108%) due to mutual enhancement effects. Skin disposition indicated that DEET produced a faster transdermal permeation rate and higher systemic absorption extent, but oxybenzone formed a concentrated depot within the skin and delivered the content slowly over the time. In vivo AUC{sub P}/MRT of DEET and oxybenzone was increased by 37%/17% and 63%/10% when the two compounds were used together. No DEET was detected from the urine samples 48 h after the application. Tape stripping seemed to be a satisfactory approach for quantitative assessment of DEET and oxybenzone penetration into the stratum corneum. It was also concluded that pharmacological and toxicological perspectives from concurrent application of insect repellent and sunscreen products require further evaluation to ensure use efficacy and safety of these common consumer healthcare products.

Kasichayanula, Sreeneeranj [Faculty of Pharmacy, University of Manitoba, 50 Sifton Road, Winnipeg, MB, R3T 2N2 (Canada); House, James D. [Department of Animal Science, University of Manitoba, Winnipeg, MB, R3T 2N2 (Canada); Wang Tao [Faculty of Pharmacy, University of Manitoba, 50 Sifton Road, Winnipeg, MB, R3T 2N2 (Canada); Gu Xiaochen [Faculty of Pharmacy, University of Manitoba, 50 Sifton Road, Winnipeg, MB, R3T 2N2 (Canada)], E-mail: xgu@cc.umanitoba.ca

2007-09-01T23:59:59.000Z

273

Modeling  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

a single-fluid diffuse interface model in the ALE-AMR hydrodynamics code to simulate surface tension effects. We show simula- tions and compare them to other surface tension...

274

Modeling  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

sion effects. We show the result of a test case, and compare it to the result without surface tension. The model describes droplet formation nicely. Application The ARRA-funded...

275

Human hybrid hybridoma  

SciTech Connect (OSTI)

Hybrid hybridomas are obtained by fusion of two cells, each producing its own antibody. Several authors have reported the construction of murine hybrid hybridomas with the aim to obtain bispecific monoclonal antibodies. The authors have investigated, in a model system, the feasibility of constructing a human hybrid hybridoma. They fused two monoclonal cell lines: an ouabain-sensitive and azaserine/hypoxanthine-resistant Epstein-Barr virus-transformed human cell line that produces an IgG1kappa antibody directed against tetanus toxiod and an azaserine/hypoxanthine-sensitive and ouabain-resistant human-mouse xenohybrid cell line that produces a human IgG1lambda antibody directed against hepatitis-B surface antigen. Hybrid hybridoma cells were selected in culture medium containing azaserine/hypoxanthine and ouabain. The hybrid nature of the secreted antibodies was analyzed by means of two antigen-specific immunoassay. The results show that it is possible, with the combined use of transformation and xenohybridization techniques, to construct human hybrid hybridomas that produce bispecific antibodies. Bispecific antibodies activity was measured by means of two radioimmunoassays.

Tiebout, R.F.; van Boxtel-Oosterhof, F.; Stricker, E.A.M.; Zeijlemaker, W.P.

1987-11-15T23:59:59.000Z

277

Solar radiation and human health  

Science Journals Connector (OSTI)

The Sun has played a major role in the development of life on Earth. In Western culture, people are warned against Sun exposure because of its adverse effects: erythema, photoimmunosuppression, photoageing, photocarcinogenesis, cataracts and photokeratitis. However, Sun exposure is also beneficial, since moderate doses give beneficial physiological effects: vitamin D synthesis, reduction of blood pressure and mental health. Shortage of Sun exposure may be even more dangerous to human health than excessive exposure. Avoiding Sun exposure leads to vitamin D deficiency which is associated not only with rickets and osteomalacia, but also with increased risk of cardiovascular disease, multiple sclerosis, rheumatoid arthritis, diabetes, influenza, many types of cancer and adverse pregnancy outcomes. Solar radiation induces nitric oxide release in tissue and immediate pigment darkening which certainly play important roles, although these are still unknown. Action spectra relevant for health are described. We will also review what is known about spectral and intensity variations of terrestrial solar radiation as well as its penetration through the atmosphere and into human skin and tissue.

Asta Juzeniene; Pål Brekke; Arne Dahlback; Stefan Andersson-Engels; Jörg Reichrath; Kristin Moan; Michael F Holick; William B Grant; Johan Moan

2011-01-01T23:59:59.000Z

278

Modeling  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

ALE-AMR ALE-AMR code Wangyi Liu, John Bernard, Alex Friedman, Nathan Masters, Aaron Fisher, Velemir Mlaker, Alice Koniges, David Eder June 4, 2011 Abstract In this paper we describe an implementation of a single-fluid inter- face model in the ALE-AMR code to simulate surface tension effects. The model does not require explicit information on the physical state of the two phases. The only change to the existing fluid equations is an additional term in the stress tensor. We show results of applying the model to an expanding Al droplet surrounded by an Al vapor, where additional droplets are created. 1 Introduction The Neutralized Drift Compression Experiment II (NDCX II) is an induction accelerator planned for initial commissioning in 2012. The final design calls for a 3 MeV, Li+ ion beam, delivered in a bunch with characteristic pulse duration of 1 ns, and transverse dimension of order 1 mm. The

279

Abstract A05: The Mouse Tumor Biology (MTB) Database: An electronic tool for identifying and evaluating mouse and PDX models of human cancer  

Science Journals Connector (OSTI)

...human tumors and provides freely available web access to these data. MTB integrates data...cancer research community and has developed a web-based system to facilitate submission...MPD), the Biology of the Mammary Gland Web Site, and the NCI Mouse Repository. MTB...

Dale A. Begley; Debra M. Krupke; Steven B. Neuhauser; Joel E. Richardson; John P. Sundberg; Carol J. Bult; Janan T. Eppig

2014-11-01T23:59:59.000Z

280

Phenotypic Characteristics of Cell Lines Derived from Disseminated Cancer Cells in Bone Marrow of Patients with Solid Epithelial Tumors: Establishment of Working Models for Human Micrometastases  

Science Journals Connector (OSTI)

...serum deprivation. Exp. Cell Res., 224: 208-213, 1996. 59 Van der Velde-Zimmermann D., Verdaasdonk M. A., Rademakers L. H., De Weger R. A., Van den Tweel J. G., Jogling P. Fibronectin distribution in human bone marrow stroma: matrix...

Elmar Putz; Klaus Witter; Sonja Offner; Peter Stosiek; Alfred Zippelius; Judith Johnson; Robert Zahn; Gert Riethmüller; Klaus Pantel

1999-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "human skin model" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


281

Particles and People: Aerosol Movement Into and Around the Human Body  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Particles and People: Aerosol Movement Into and Around the Human Body Particles and People: Aerosol Movement Into and Around the Human Body Speaker(s): Miriam Byrne Date: April 14, 2006 - 12:00pm Location: Bldg. 90 Miriam Byrne is a participating guest in the Airflow and Pollutant Transport Group at LBL. She is an academic member of staff in the Physics Department at the National University of Galway, Ireland. Her research interests, primarily funded by European Commission radiation protection programs, focus on the mechanisms of aerosol transport to and from human body surfaces. Over the last ten years, she has been involved in tracer aerosol experiments to determine rates of particle deposition and resuspension from skin, hair and clothing, as well as studying particle transport into skin pores and hair follicles, and contact transfer from

282

New imaging technique gets under the skin...deep  

SciTech Connect (OSTI)

Using a combination of simple optical techniques, plain old white light, and image processing, two Lawrence Livermore researchers and a colleague from the City College of New York (CCNY) have developed a technique for imaging tissue structures--tendons, veins, tumors--deep beneath the skin. The ultimate goal of this research is to dramatically improve the ability to perform minimally invasive cancer detection. ''With a technique called spectral polarization difference imaging [SPDI], we use different wavelengths of light to reach different depths. We also use the polarization properties of the light to help us select the light that penetrates into the tissue and is reflected back out of the tissue as opposed to the light that bounces off the tissue surface,'' says Livermore physicist Harry Radousky, acting Director of University Relations. ''We then image the tissue structures at the different depths, based on how these structures absorb, scatter, and depolarize light. This technique, combined with fiber optics, charge-coupled-device cameras, and image enhancement calculations, allows us to image up to 1.5 centimeters inside tissue, far deeper than the millimeter depths managed by other existing optical techniques.'' The basic research to develop this technique was funded by the Department of Energy through one of its centers of excellence in laser medicine--the DOE Center for Laser Imaging and Cancer Diagnostics directed by Robert Alfano, M.D., at CCNY. A branch of this center is hosted at the Laboratory within the Materials Research Institute. wavelengths in the visible spectrum are scattered and absorbed within the tissue. For even longer wavelengths--those in the near-infrared spectral region--scattering and absorption of the photons is even further reduced.'' The light that passes through the filter then passes through a polarizer. The light that finally hits the tissue sample is thus not only of a given wavelength but also of a selected polarization. As photons penetrate the tissue, they interact with various tissue structures that may have optical properties different from those of the host tissue. Finally, some of the injected photons emerge from the tissue in the backscattering direction. The intensity of the backscattered light depends on the optical characteristics of the tissue at the sample's surface as well as below its surface at a particular location. Light that reflects from the surface (known as a spectral reflection) is polarized and can be removed with a second polarizer set to reject this light. This phenomenon is similar to the way sunglasses work to remove the polarized glare from surfaces, such as the water surface in a swimming pool. The light that backscatters from somewhere below the surface of the tissue is depolarized and consequently can pass through this second polarizer. This remaining light passes through a 50-millimeter camera lens, which is coupled to a CCD detector that captures the image in an exposure of a few milliseconds.

Radousky, H; Demos, S

2000-11-01T23:59:59.000Z

283

Relation Between Tolerance Dose of Skin and Boron-10 Concentration in Neutron Capture Therapy for Cutaneous Melanoma  

Science Journals Connector (OSTI)

In boron neutron capture therapy of cutaneous melanoma1, damage to scalp, facial skin and eyes must be strictly avoided. Two basic irradiation conditions follow: (1) ...

Tooru Kobayashi; Keiji Kanda; Yowri Ujeno…

1992-01-01T23:59:59.000Z

284

16.459 Humans & Automation Seminar February 6, 2002  

E-Print Network [OSTI]

simulations Automated bank teller system design ACT-R Modeling problem solving and learning Various problem ­ To provide rapid prototype simulator to examine human operator performance as a function of human interface16.459 Humans & Automation Seminar February 6, 2002 Miwa Hayashi #12;!Human-Machine System Design

Goldwasser, Shafi

285

CAMB 630 Topics in Human Genetics and Disease Course Directors  

E-Print Network [OSTI]

on the foundations of the Human Genome Project and parallel efforts in model organisms, research in human genetics in Human Genetics and Disease: I. Genome architecture and instability (Spinner) Chromosome specific of Mendelian disease Developmental pathways and genetic disease III. Human genomic variation and disease

Plotkin, Joshua B.

286

CS 4317 Human-Computer Interaction Course Number: CS4317  

E-Print Network [OSTI]

interaction. Theory of human-computer interaction. Development methods for interfaces such as user1 CS 4317 Human-Computer Interaction Course Number: CS4317 Course Title: Human-Computer Interaction Course Instructors Nigel Ward Course Description: CS4317: Models and methods of human-computer

Ward, Karen

287

A Solar Re-Skin at FedEx Field | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

A Solar Re-Skin at FedEx Field A Solar Re-Skin at FedEx Field A Solar Re-Skin at FedEx Field August 2, 2011 - 10:40am Addthis Ramamoorthy Ramesh Former Director, SunShot Initiative & Solar Energy Technologies Program What does this mean for me? Investments by major companies like the Redskins show the growing market demand for solar technology, as the SunShot Initiative works to accelerate this growth to make solar energy cheaper. If solar power could score a touchdown, then this week's news would definitely count. On Wednesday, the Washington Redskins announced they are working with NRG Energy, one of America's largest energy companies, to bring renewable energy to the football franchise. This means more than just a few panels on the roof. Through the partnership, NRG will install 8,000 translucent solar panels to

288

A Solar Re-Skin at FedEx Field | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

A Solar Re-Skin at FedEx Field A Solar Re-Skin at FedEx Field A Solar Re-Skin at FedEx Field August 2, 2011 - 10:40am Addthis Ramamoorthy Ramesh Former Director, SunShot Initiative & Solar Energy Technologies Program What does this mean for me? Investments by major companies like the Redskins show the growing market demand for solar technology, as the SunShot Initiative works to accelerate this growth to make solar energy cheaper. If solar power could score a touchdown, then this week's news would definitely count. On Wednesday, the Washington Redskins announced they are working with NRG Energy, one of America's largest energy companies, to bring renewable energy to the football franchise. This means more than just a few panels on the roof. Through the partnership, NRG will install 8,000 translucent solar panels to

289

Chronic cellular responses of rat skin to 13 Mev proton irradiation  

E-Print Network [OSTI]

CHRONIC CELLULAR RESPONSES OF RAT SKIN TO 13 MEV PROTON IRRADIATION A Thesis by DONALD KING HINKLE, D. V. M. Submitted to the Graduate College of the Texas AErM University in partial fulfillment of the requirements for the degree of MASTER... OF SCIENCE August 1966 Major Subject: Laboratory Animal Medicine CHRONIC CELLULAR RESPONSES OF RAT SKIN TO 13 MEV PROTON IRRADIATION A Thesis by DONALD KING HINKLE, D. V. M. Submitted to the Graduate College of the Texas ARM University in partial...

Hinkle, Donald King

2012-06-07T23:59:59.000Z

290

IEEE TRANSACTIONS ON SYSTEMS, MAN, AND CYBERNETICS--PART A: SYSTEMS AND HUMANS, VOL. 36, NO. 5, SEPTEMBER 2006 943 Extending the Decision Field Theory to Model  

E-Print Network [OSTI]

, SEPTEMBER 2006 943 Extending the Decision Field Theory to Model Operators' Reliance on Automation by describing a quantitative model of trust in automation. We extend decision field theory (DFT) to describe the multiple sequential decisions that characterize reliance on au- tomation in supervisory control situations

Lee, John D.

291

New Electronic Sensors Stick to Your Skin -Heart Rate Monitors -Popular Mechanics http://www.popularmechanics.com/science/health/breakthroughs/new-electronic-sensors-stick-to-your-skin?click=pm_latest[8/14/2011 5:59:45 AM  

E-Print Network [OSTI]

New Electronic Sensors Stick to Your Skin - Heart Rate Monitors - Popular Mechanics http://www Electronic Sensors That Stick to Your Skin Like Temporary Tattoos Nice tattoo. Or is it a heart-rate monitor to measure the electrical activity of the heart, muscles and brain. And using the same principles behind

Rogers, John A.

292

Transport lattice models of heat transport in skin with spatially heterogeneous, temperature-dependent perfusion  

E-Print Network [OSTI]

Background: Investigation of bioheat transfer problems requires the evaluation of temporal and spatial distributions of temperature. This class of problems has been traditionally addressed using the Pennes bioheat equation. ...

Martin, Gregory T

293

Space radiation-induced bystander signaling in 2D and 3D skin tissue models  

E-Print Network [OSTI]

Space radiation poses a significant hazard to astronauts on long-duration missions, and the low fluences of charged particles characteristic of this field suggest that bystander effects, the phenomenon in which a greater ...

Lumpkins, Sarah B

2012-01-01T23:59:59.000Z

294

Repair Capacity for UV Light–Induced DNA Damage Associated with Risk of Nonmelanoma Skin Cancer and Tumor Progression  

Science Journals Connector (OSTI)

...reactivation|DNA repair capacity|epidemiology|skin...increasing levels of solar UV radiation (2-4...studying the DNA repair capacity (DRC) as a marker for...keratosis with cumulative solar ultraviolet exposure...influence the DNA repair capacity of normal and skin cancer-affected...

Li-E Wang; Chunying Li; Sara S. Strom; Leonard H. Goldberg; Abenaa Brewster; Zhaozheng Guo; Yawei Qiao; Gary L. Clayman; J. Jack Lee; Adel K. El-Naggar; Victor G. Prieto; Madeleine Duvic; Scott M. Lippman; Randal S. Weber; Margaret L. Kripke; and Qingyi Wei

2007-11-01T23:59:59.000Z

295

Epigallocatechin-3-gallate (EGCG) protects skin cells from ionizing radiation via heme oxygenase-1 (HO-1) overexpression  

Science Journals Connector (OSTI)

......cancer [19]. However, along with the destruction of tumors, surrounding normal tissues may also be injured, including brain, lung, intestine and skin. Skin covers the largest area of the body and functions to protect the body from all types of noxious......

Wei Zhu; Jing Xu; Yangyang Ge; Han Cao; Xin Ge; Judong Luo; Jiao Xue; Hongying Yang; Shuyu Zhang; Jianping Cao

2014-11-01T23:59:59.000Z

296

Climate: monthly and annual average Earth skin temperature GIS data at  

Open Energy Info (EERE)

Earth skin temperature GIS data at Earth skin temperature GIS data at one-degree resolution of the World from NASA/SSE Dataset Summary Description (Abstract): Earth Skin Temperature (° C)NASA Surface meteorology and Solar Energy (SSE) Release 6.0 Data Set (Nov 2007)22-year Monthly & Annual Average (July 1983 - June 2005)Parameter: Earth Skin Temperature (deg C)Internet: http://eosweb.larc.nasa.gov/sse/Note 1: SSE Methodology & Accuracy sections onlineNote 2: Lat/Lon values indicate the lower left corner of a 1x1 degree region. Negative values are south and west; positive values are north and east. Boundaries of the -90/-180 region are -90 to -89 (south) and -180 to -179 (west). The last region, 89/180, is bounded by 89 to 90 (north) and 179 to 180 (east). The mid-point of the region is +0.5 added to the the Lat/Lon value. These data are

297

A generalized algorithm for retrieving cloudy sky skin temperature from satellite thermal infrared radiances  

E-Print Network [OSTI]

A generalized algorithm for retrieving cloudy sky skin temperature from satellite thermal infrared Earth and Atmospheric Sciences, Georgia Institute of Technology, Atlanta Abstract. A physical algorithm that of Jin [2000]. Two neighboring pixels over the same land cover have a difference in temperature largely

Jin, Menglin

298

Was skin cancer a selective force for black pigmentation in early hominin evolution?  

Science Journals Connector (OSTI)

...year-round UVB exposures, including Tanzania [97,109-111], Cameroon...albinos with skin cancer in Tanzania recorded in 1985, 50% of...Europeans and Africans against solar ultraviolet radiation. J...teaching hospital in northwestern Tanzania: a retrospective review of...

2014-01-01T23:59:59.000Z

299

Inhibitory Effect of Green Tea on the Growth of Established Skin Papillomas in Mice  

Science Journals Connector (OSTI)

...Preparation and Composition of Green Tea Polyphenol Fraction. One hundred g of green tea leaves were extracted 3...filtered after each extraction. Solvent was removed from the combined...ml 6657 INHIBITORY EFFECT OF GREEN TEA ON THE GROWTH OF SKIN PAPILLOMAS...

Zhi Y. Wang; Mou-Tuan Huang; Chi-Tang Ho; Richard Chang; Wei Ma; Thomas Ferraro; Kenneth R. Reuhl; Chung S. Yang; and Allan H. Conney

1992-12-01T23:59:59.000Z

300

Brown algae polyphenols prevent UVB-induced skin carcinogenesis in SKH-1 mice  

Science Journals Connector (OSTI)

...Assoc Cancer Res, Volume 47, 2006 Brown algae polyphenols prevent UVB-induced skin...showed that polyphenols extracted from brown algae have potent antioxidant activities. In...feeding and topical application of brown algae polyphenols on UVB radiation-induced...

Hyejeong Hwang; Tong Chen; Ronard G. Nines; Sarah M. Peschke; Hyeon-Cheol Shin; Gary D. Stoner

2006-04-15T23:59:59.000Z

Note: This page contains sample records for the topic "human skin model" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


301

The average person sheds 40 pounds of skin during his or her lifetime. That's the  

E-Print Network [OSTI]

Q: MSU N 19 o. The average person sheds 40 pounds of skin during his or her lifetime. That whether they are facts or opinions. Fact or opinion? A fact is something that can be tested. An opinion is something that someone thinks or believes. 1. Wooly mammoths are extinct. fact opinion 2. Ear wax can

302

Norathyriol Suppresses Skin Cancers Induced by Solar Ultraviolet Radiation by Targeting ERK Kinases  

Science Journals Connector (OSTI)

...UVB (5% of the total solar UV radiation) is mainly...norathyriol strongly suppresses solar UVinduced mouse skin...structure was subjected to energy minimization using the...hairless mice exposed to solar UV. The inhibition by...U.S. Department of Energy, Office of Basic Energy...

Jixia Li; Margarita Malakhova; Madhusoodanan Mottamal; Kanamata Reddy; Igor Kurinov; Andria Carper; Alyssa Langfald; Naomi Oi; Myoung Ok Kim; Feng Zhu; Carlos P. Sosa; Keyuan Zhou; Ann M. Bode; and Zigang Dong

2012-01-01T23:59:59.000Z

303

Sunlight UV-Induced Skin Cancer Relies upon Activation of the p38? Signaling Pathway  

Science Journals Connector (OSTI)

...Lachiewicz A, Pestak C Thomas N.Solar UV exposure and mortality from...phosphorylation of MKP1 protein prevents solar ultraviolet light-induced...suppresses skin cancers induced by solar ultraviolet radiation by targeting...Gasparro FP Uitto J.UVA-340 as energy source, mimicking natural sunlight...

Kangdong Liu; Donghoon Yu; Yong-Yeon Cho; Ann M. Bode; Weiya Ma; Ke Yao; Shengqing Li; Jixia Li; G. Tim Bowden; Ziming Dong; and Zigang Dong

2013-04-01T23:59:59.000Z

304

Vibrio furnissii: an Unusual Cause of Bacteremia and Skin Lesions after Ingestion of Seafood  

Science Journals Connector (OSTI)

...Bacteremia and Skin Lesions after Ingestion of Seafood Catherine Derber 1 * Philip Coudron 2...underlying comorbidities who are exposed to seafood. CASE REPORT A 62-year-old man from...ingesting contaminated raw or undercooked seafood or after contact with warm marine environments...

Catherine Derber; Philip Coudron; Cheryl Tarr; Lori Gladney; Maryann Turnsek; Shivanjali Shankaran; Edward Wong

2011-03-30T23:59:59.000Z

305

ON THE INFLUENCE OF THE GEOMETRY ON SKIN EFFECT IN ELECTROMAGNETISM  

E-Print Network [OSTI]

ON THE INFLUENCE OF THE GEOMETRY ON SKIN EFFECT IN ELECTROMAGNETISM GABRIEL CALOZ, MONIQUE DAUGE, ERWAN FAOU, VICTOR P´ERON ABSTRACT. We consider the equations of electromagnetism set on a domain made in electromagnetism. This effect describes the rapid decay of electromagnetic fields with depth inside a metallic

Dauge, Monique

306

CancerTherapy Skin Cooling Anthony Alleman, Duane Bywaters, David Chadburn, Drew Sparks  

E-Print Network [OSTI]

printed cooling pad with 9 ports, the final cooling pad is ABS 3D printed with a curved surface and 11 ports. ABS 3D printed CP with inner channel and 9 ports, vertical flow. 11 ports angled towards membrane ultrasound procedure to concentrate acoustic energy beneath the skin's Required heat transfer coefficients

Provancher, William

307

Original Contribution Arsenic Exposure from Drinking Water and Risk of Premalignant Skin Lesions  

E-Print Network [OSTI]

Original Contribution Arsenic Exposure from Drinking Water and Risk of Premalignant Skin Lesions, 2006. Millions of persons around the world are exposed to low doses of arsenic through drinking water from drinking water over a significant period of time. The authors evaluated dose-response relations

van Geen, Alexander

308

Does Low Penetration of Human Skin by the Normal Mode Ruby Laser Account for Poor Permanent Depilatory Success Rates?  

Science Journals Connector (OSTI)

...Studies reported to date have shown a good depilatory response from patients treated with the normal mode ruby laser (NMRL) over 12 weeks, but a low response over a time period greater than this. Previous publ...

A. Topping; D. Gault; A. Grobbelaar; R. Sanders; C. Green…

2001-06-01T23:59:59.000Z

309

Lasers in Surgery and Medicine 38:137141 (2006) Thermal Responses of Ex Vivo Human Skin During Multiple  

E-Print Network [OSTI]

Departamento de Optica, Instituto Nacional de Astrofisica, Optica y Electronica, Puebla, Mexico 3 Department

Aguilar, Guillermo

310

Comparative 32P-Analysis of Cigarette Smoke-induced DNA Damage in Human Tissues and Mouse Skin  

Science Journals Connector (OSTI)

...5 Murea.pH3.64.2 M lithium formate, 7.5 Murea.pH3.80.8 M lithium chloride, 0.5 MTrisMCI, 8.5 M urea, pH8.00.6 M lithium chloride, 0.5 MTrisHCI...labeled quantitatively with excess ATP, and was calculated according...

Erika Randerath; Tommie A. Avitts; M. Vijayaraj Reddy; Robert H. Miller; Richard B. Everson; and Kurt Randerath

1986-11-01T23:59:59.000Z

311

An integrated monitoring/modeling framework for assessing human-nature interactions in urbanizing watersheds: Wappinger and Onondaga Creek watersheds, New York, USA  

Science Journals Connector (OSTI)

In much of the world, rapidly expanding areas of impervious surfaces due to urbanization threaten water resources. Although tools for modeling and projecting land use change and water quantity and quality exist independently, to date it is rare to find ... Keywords: Impervious surface, Remote sensing, Socio-economic factors, Uncertainty, Urbanization, Water resources

Bongghi Hong; Karin E. Limburg; Myrna H. Hall; Giorgos Mountrakis; Peter M. Groffman; Karla Hyde; Li Luo; Victoria R. Kelly; Seth J. Myers

2012-06-01T23:59:59.000Z

312

Introduction Uniform Estimates for Transmission Problems 3D Multiscaled Asymptotic Expansion Numerical Simulations Skin-Effect Description in Electromagnetism with a  

E-Print Network [OSTI]

Numerical Simulations Skin-Effect Description in Electromagnetism with a Scaled Asymptotic Expansion Gabriel.08.2009 V. P´eron Skin-Effect Description in Electromagnetism with a Scaled Asymptotic Expansion 1 / 32 and Electromagnetism MONIQUE DAUGE, ERWAN FAOU, VICTOR P ´ERON (2009) Asymptotic Behavior at High Conductivity of Skin

Paris-Sud XI, Université de

313

Data-driven human body morphing  

E-Print Network [OSTI]

This thesis presents an efficient and biologically informed 3D human body morphing technique through data-driven alteration of standardized 3D models. The anthropometric data is derived from a large empirical database and processed using principal...

Zhang, Xiao

2005-11-01T23:59:59.000Z

314

Energy-dependence of skin-mode fraction in $E1$ excitations of neutron-rich nuclei  

E-Print Network [OSTI]

We have extensively investigated characters of the low-energy $E1$ strengths in $N>Z$ nuclei, by analyzing the transition densities obtained by the HF+RPA calculations with several effective interactions. Crossover behavior has been confirmed, from the skin mode at low energy to the $pn$ mode at higher energy. Decomposing the $E1$ strengths into the skin-mode, $pn$-mode and interference fractions, we show that the ratio of the skin-mode strength to the full strength may be regarded as a generic function of the excitation energy, insensitive to nuclides and effective interactions, particularly beyond Ni.

Nakada, H; Sawai, H

2015-01-01T23:59:59.000Z

315

active human visceral: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Transporter Nurse Chaplain Occupational Contractor, Anis 28 Mining Models of Human Activities from the Web Mike Perkowitz Computer Technologies and Information Sciences Websites...

316

Artificial neural networks for processing fluorescence spectroscopy data in skin cancer diagnostics  

Science Journals Connector (OSTI)

Over the years various optical spectroscopic techniques have been widely used as diagnostic tools in the discrimination of many types of malignant diseases. Recently, synchronous fluorescent spectroscopy (SFS) coupled with chemometrics has been applied in cancer diagnostics. The SFS method involves simultaneous scanning of both emission and excitation wavelengths while keeping the interval of wavelengths (constant-wavelength mode) or frequencies (constant-energy mode) between them constant. This method is fast, relatively inexpensive, sensitive and non-invasive. Total synchronous fluorescence spectra of normal skin, nevus and melanoma samples were used as input for training of artificial neural networks. Two different types of artificial neural networks were trained, the self-organizing map and the feed-forward neural network. Histopathology results of investigated skin samples were used as the gold standard for network output. Based on the obtained classification success rate of neural networks, we concluded that both networks provided high sensitivity with classification errors between 2 and 4%.

L Lenhardt; I Zekovi?; T Drami?anin; M D Drami?anin

2013-01-01T23:59:59.000Z

317

Influence of the single-particle structure on the nuclear surface and the neutron skin  

E-Print Network [OSTI]

We analyze the influence of the single-particle structure on the neutron density distribution and the neutron skin in Ca, Ni, Zr, Sn, and Pb isotopes. The nucleon density distributions are calculated in the Hartree-Fock+BCS approach with the SLy4 Skyrme force. A close correlation is found between the quantum numbers of the valence neutrons and the changes in the position and the diffuseness of the nuclear surface, which in turn affect the neutron skin thickness. Neutrons in the valence orbitals with low principal quantum number and high angular momentum mainly displace the position of the neutron surface outwards, while neutrons with high principal quantum number and low angular momentum basically increase the diffuseness of the neutron surface. The impact of the valence shell neutrons on the tail of the neutron density distribution is discussed.

M. Warda; M. Centelles; X. Vinas; X. Roca-Maza

2014-04-03T23:59:59.000Z

318

Effect of Ion Skin Depth on Relaxation of Merging Spheromaks to a Field-Reversed Configuration  

Science Journals Connector (OSTI)

The effect of ion skin depth on the relaxation of merging spheromaks to a field-reversed configuration (FRC) is studied experimentally for a wide range of size parameter S* (ratio of minor radius to ion skin depth) from 1 to 7. The two merging spheromaks are observed to relax to an FRC or a new spheromak depending on whether the initial poloidal eigenvalue is smaller or larger than a threshold value. The bifurcation value is found to increase with decreasing size parameter S*, indicating that the low-S* condition provides a wide bifurcated range of relaxation to an FRC. The FRC-style relaxation under the low-S* conditions was accompanied by the suppression of the low-n modes (n is the toroidal mode number) activity. The fast rotations of the modes were followed by suppression of the low-n modes.

Eiichirou Kawamori and Yasushi Ono

2005-08-18T23:59:59.000Z

319

THERMAL SKIN DAMAGE AND MOBILE PHONE USE Elmountacer Billah Elabbassi(1)  

E-Print Network [OSTI]

THERMAL SKIN DAMAGE AND MOBILE PHONE USE Elmountacer Billah Elabbassi(1) , René de Sèze(2) (1 sensation of thé cheek. Thèse symptoms may be due to thermal insulation, conduction of thé heat produced in thé phone by thé battery currents and running of thé radiofrequency (RF) electronic circuits

Paris-Sud XI, Université de

320

Dose profiles through the dermis for on and off-skin hot particle exposures  

E-Print Network [OSTI]

reports measurements of depth-dose profiles for on- and off-skin hot particle exposures using radiochromic dye film. Dose profiles from both a "Co hot particle, and activated depleted uranium oxide microspheres were measured with the film. Exposures.... The thickness of the hot particle was approximately 250 ym. The other type of hot particle used in this project was fabricated at the Nuclear Science Center INSC) at Texas AIIrM University. For these sources, depleted uranium oxide microspheres were activated...

Shaw, Kimberly Rochelle

2012-06-07T23:59:59.000Z

Note: This page contains sample records for the topic "human skin model" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


321

Modeling reaction time within a traffic simulation model  

E-Print Network [OSTI]

Human reaction time has a substantial effect on modeling of human behavior at a microscopic level. Drivers and pedestrian do not react to an event instantaneously; rather, they take time to perceive the event, process the ...

Basak, Kakali

322

Cognitive Science (Humanities)  

E-Print Network [OSTI]

Cognitive Science (Humanities) The University of Edinburgh College of Humanities and Social Science: Cognitive Science (Humanities) BSc Honours in: Cognitive Science Please see separate information sheets the disciplines that contribute to the study of human cognition. The Cognitive Science programme at Edinburgh

Schnaufer, Achim

323

Effect of dietary polyunsaturated fatty acid and related nutrients on plasma lipids, and skin and hair coat condition in canines  

E-Print Network [OSTI]

phospholipid fatty acids were determined at each collection period. Serum zinc concentrations were analyzed on wk 12, 14, and 24. The hypothesis was that a diet containing increased LA, ALA, and zinc concentrations (diet C) would show improvements of skin...

Hester, Shaleah Lynnae

2004-11-15T23:59:59.000Z

324

Identifying Latent Classes of Adults at Risk for Skin Cancer Based on Constitutional Risk and Sun Protection Behavior  

Science Journals Connector (OSTI)

...these habits were greater for those with higher...skin cancer. The classes seemed to represent...numbers indicating greater risk in the class (Tables 1 and 2...higher risk reported greater sun protection practices. Latent Class Validation The LCA...

Alana D. Steffen; Karen Glanz; and Lynne R. Wilkens

2007-07-01T23:59:59.000Z

325

Low-temperature atmospheric plasma increases the expression of anti-aging genes of skin cells without causing cellular damages  

Science Journals Connector (OSTI)

Efforts to employ various types of plasma in the field of skin care have increased consistently because it can regulate many biochemical reactions that are normally unaffected by light-based therapy. One metho...

Jeong-Hae Choi; Hyun-Wook Lee; Jae-Koo Lee…

2013-03-01T23:59:59.000Z

326

Human integration in the lifecycle of aviation systems  

Science Journals Connector (OSTI)

While Human Factors is perhaps the most critical discipline to improving aviation safety, research and development is disproportionately small-scale, fragmented and unsustained. The key issue is the delivery of Human Factors knowledge throughout the ... Keywords: Human Factors, aviation, innovation, operational performance, research capability, safety, system improvement, system life-cycle, system models

Nick McDonald

2007-07-01T23:59:59.000Z

327

Prediction of Complete Gene Structures in Human Genomic DNA  

E-Print Network [OSTI]

and RNA splicing. On the other hand, with the recent shift in the emphasis of the Human Genome ProjectPrediction of Complete Gene Structures in Human Genomic DNA Chris Burge* and Samuel Karlin model of the gene structure of human genomic sequences which incorporates descriptions of the basic

Shatkay, Hagit

328

Quantitative studies of rattlesnake (Crotalus atrox: venom, venom fractions, and rabbit antivenom: Lethality, skin sensitivity, and antibody characterization.  

E-Print Network [OSTI]

QUANTITATIVE STUDIES OF RATTLESNAKE (CROTALUS ATROX) VENOM, VENOM FRACTIONS, AND RABBIT ANTIVENOM: LETHALITY, SKIN SENSITIVITY, AND ANTIBODY CHARACTERIZATION A Thesis By RICHARD PATTON BRADBURY Submitted to the Graduate College of the Texas...: LETHALITY, SKIN SENSITIVITY, AND ANTIBODY CHARACTERIZATION A Thesis By RICHARD PATTON BRADBURY Approved as to style and content by: (Chairman of Committee) Q(cf f. 4&a (Member) (Coordinator, Space Medicine (Member) Program and Member) August 1967...

Bradbury, Richard Patton

2012-06-07T23:59:59.000Z

329

Humanity’s unsustainable environmental footprint  

Science Journals Connector (OSTI)

...biodiversity loss or effects on human health or...billion m 3 /year (average for 1996 to 2005...billion m 3 /year (average for 1996 to...emissions from fossil fuels—part of humanity...products in their price—for example, by...The EF of the average global citizen...so-called rebound effect (44). Profound...

Arjen Y. Hoekstra; Thomas O. Wiedmann

2014-06-06T23:59:59.000Z

330

The SACADA database for human reliability and human performance  

SciTech Connect (OSTI)

Lack of appropriate and sufficient human performance data has been identified as a key factor affecting human reliability analysis (HRA) quality especially in the estimation of human error probability (HEP). The Scenario Authoring, Characterization, and Debriefing Application (SACADA) database was developed by the U.S. Nuclear Regulatory Commission (NRC) to address this data need. An agreement between NRC and the South Texas Project Nuclear Operating Company (STPNOC) was established to support the SACADA development with aims to make the SACADA tool suitable for implementation in the nuclear power plants' operator training program to collect operator performance information. The collected data would support the STPNOC's operator training program and be shared with the NRC for improving HRA quality. This paper discusses the SACADA data taxonomy, the theoretical foundation, the prospective data to be generated from the SACADA raw data to inform human reliability and human performance, and the considerations on the use of simulator data for HRA. Each SACADA data point consists of two information segments: context and performance results. Context is a characterization of the performance challenges to task success. The performance results are the results of performing the task. The data taxonomy uses a macrocognitive functions model for the framework. At a high level, information is classified according to the macrocognitive functions of detecting the plant abnormality, understanding the abnormality, deciding the response plan, executing the response plan, and team related aspects (i.e., communication, teamwork, and supervision). The data are expected to be useful for analyzing the relations between context, error modes and error causes in human performance.

Y. James Chang; Dennis Bley; Lawrence Criscione; Barry Kirwan; Ali Mosleh; Todd Madary; Rodney Nowell; Robert Richards; Emilie M. Roth; Scott Sieben; Antonios Zoulis

2014-05-01T23:59:59.000Z

331

Delivering HCI modelling to designers: A framework and case study of cognitive modelling  

Science Journals Connector (OSTI)

......cognitive modelling Simon Buckingham Shum Nick Hammond Human-Computer Interaction Group...cognitive modelling Simon Buckin~am Shum and Nick Hammond The human-computer interaction...contrasted illustrates their respective merits and limitations. How will current work......

Simon Buckingham Shum; Nick Hammond

1994-09-01T23:59:59.000Z

332

Standardised and transparent model descriptions for agent-based models: Current status and prospects  

Science Journals Connector (OSTI)

Agent-based models are helpful to investigate complex dynamics in coupled human-natural systems. However, model assessment, model comparison and replication are hampered to a large extent by a lack of transparency and comprehensibility in model descriptions. ... Keywords: Agent-based modelling, Domain specific languages, Graphical representations, Model communication, Model comparison, Model design, Model development, Model replication, Standardised protocols

Birgit Müller, Stefano Balbi, Carsten M. Buchmann, Luís De Sousa, Gunnar Dressler, Jürgen Groeneveld, Christian J. Klassert, Quang Bao Le, James D. A. Millington, Henning Nolzen, Dawn C. Parker, J. Gary Polhill, Maja Schlüter, Jule Schulze, Nina Schwarz, Zhanli Sun, Patrick Taillandier, Hanna Weise

2014-05-01T23:59:59.000Z

333

Programming with human computation  

E-Print Network [OSTI]

Amazon's Mechanical Turk provides a programmatically accessible micro-task market, allowing a program to hire human workers. This has opened the door to a rich field of research in human computation where programs orchestrate ...

Little, Greg (Danny Greg)

2011-01-01T23:59:59.000Z

334

Is humanity sustainable?  

Science Journals Connector (OSTI)

...size, CO2 production, energy use, biomass consumption...Humans| Is humanity sustainable? | The principles and...CO(2) production, energy use, biomass consumption...Resources Ecosystem Energy-Generating Resources...November 2003 Is humanity sustainable? Charles W. Fowler1...

2003-01-01T23:59:59.000Z

335

Human Functional Brain Imaging  

E-Print Network [OSTI]

Human Functional Brain Imaging 1990­2009 September 2011 Portfolio Review #12;2 | Portfolio Review: Human Functional Brain ImagingThe Wellcome Trust is a charity registered in England and Wales, no's role in supporting human functional brain imaging and have informed `our' speculations for the future

Rambaut, Andrew

336

Biomedical Ethics & Medical Humanities  

E-Print Network [OSTI]

List Sample Elective Courses Arts & Humanities Medical Scholars: Student Projects #12;2 What is BEMHBEMH Biomedical Ethics & Medical Humanities Scholarly Concentration Stanford University School? The Biomedical Ethics and Medical Humanities Scholarly Concentration is part of the new initiative at Stanford

Ford, James

337

Human Genetics Portfolio Review  

E-Print Network [OSTI]

in providing the assessments of the Wellcome Trust's role in supporting human genetics and have informed `our to maximise the health benefits of research into the human genome remains a core component of the WellcomeHuman Genetics 1990­2009 June 2010 Portfolio Review #12;The Wellcome Trust is a charity registered

Rambaut, Andrew

338

Human Research ProgramHuman Research Program Human System Risk in Exploration and  

E-Print Network [OSTI]

Human System Risks in Exploration Missions 21SEP10 2HRP Risk Process ­ D.Grounds Presentation contentsHuman Research ProgramHuman Research Program Human System Risk in Exploration and the Human Research Program 21SEP10 1HRP Risk Process ­ D Grounds #12;Human Research ProgramHuman Research Program

Waliser, Duane E.

339

Early mucosal responses in blue catfish (Ictalurus furcatus) skin to Aeromonas hydrophila infection  

Science Journals Connector (OSTI)

Bacterial pathogens are well-equipped to detect, adhere to, and initiate infection in their finfish hosts. The mucosal surfaces of fish, such as the skin, function as the front line of defense against such bacterial insults that are routinely encountered in the aquatic environment. While recent progress has been made, and despite the obvious importance of mucosal surfaces, the precise molecular events that occur soon after encountering bacterial pathogens remain unclear. Indeed, these early events are critical in mounting appropriate responses that ultimately determine host survival or death. In the present study, we investigated the transcriptional consequences of a virulent Aeromonas hydrophila challenge in the skin of blue catfish, Ictalurus furcatus. We utilized an 8×60K Agilent microarray to examine gene expression profiles at key early timepoints following challenge (2 h, 12 h, and 24 h). A total of 1155 unique genes were significantly altered during at least one timepoint. We observed dysregulation in a number of genes involved in diverse pathways including those involved in antioxidant responses, apoptosis, cytoskeletal rearrangement, immunity, and extracellular matrix protein diversity and regulation. Taken together, A. hydrophila coordinately modulates mucosal factors across numerous cellular pathways in a manner predicted to enhance its ability to adhere to and infect the blue catfish host.

Chao Li; Benjamin Beck; Baofeng Su; Jeffery Terhune; Eric Peatman

2013-01-01T23:59:59.000Z

340

Dutch Human Geography  

Science Journals Connector (OSTI)

Human geography in the Dutch academia distinguishes itself from human geography in other continental European countries. It has developed a strong applied focus and an orientation which forms a bridge between continental European approaches in human Geography and the Anglo-Saxon human geography. The motor of this development has been the rivalry between the Amsterdam School of Sociography and the more French oriented Utrecht School of human geography. In recent times Dutch academic geography has found her way back from the more applied modes of thought to more theoretically informed debates, to which she contributes substantially.

H. Ernste; L. Smith

2009-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "human skin model" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


341

An infrared thermographic and laser doppler flowmetric investigation of skin perfusion in the forearm and finger tip : following a short period of vascular stasis .  

E-Print Network [OSTI]

??The use of Infrared Thermography to diagnose circulatory problems in the hands is based upon the assumption that a change in skin temperature can be… (more)

Stikbakke, Einar

2010-01-01T23:59:59.000Z

342

Human Intelligence: The Model Is the Message  

Science Journals Connector (OSTI)

...re-sponses to higher oil prices that must be addressed...in response to higher prices, aided, in many countries...for insulation or other oil-saving tech-niques...hand, depends on the price distribution of alternative...ofnat-ural gas and district heating (a central-ized system...

Robert J. Sternberg

1985-12-06T23:59:59.000Z

343

Statistical models for analyzing human genetic variation  

E-Print Network [OSTI]

Atlas (termed CSA-100). BCMET refers to the Evolutionary TraceAtlas (termed CSA-100). BCMET refers to the Evolutionary Trace

Sankararaman, Sriram

2010-01-01T23:59:59.000Z

344

ORISE: Human Subjects Protection  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Human Subjects Protection Human Subjects Protection The Oak Ridge Institute for Science and Education (ORISE) performs technical assessments to assist U.S. Department of Energy (DOE) laboratories involved in human subjects research projects. Under DOE Order and Policy 443.1A, Protection of Human Subjects, and 10 CFR 745, DOE employees and contractors are expected to protect the rights and welfare of human research subjects. In support of the DOE Office of Science and the Human Subjects Protection Program (HSPP), ORISE has most recently assisted with the development and distribution of tools to address classified research and to track potential human social cultural behavior systems (HSCB) research conducted by DOE laboratories. Examples of products that ORISE has developed in support of the HSPP

345

Jones, G., & Ritter, F. E. (2000). Over-estimating cognition time: The benefits of using a task simulation. In Simulating Human Agents, American Association for Artificial Intelligence Fall  

E-Print Network [OSTI]

architectures began incorporating simulation envir of human behavior are most worth capturing in a human modeling architectures? This paper presents a case, the model of the task may have been developed in an architecture or modelling environment for which

Ritter, Frank

346

ISSUE 1 | SPRING 2014 BRINGING CUTTING-EDGE SCIENCE INTO THE CLASSROOM UNDER YOUR SKIN  

E-Print Network [OSTI]

more resources at www. wellcome.ac.uk/bigpicture/ proteins. inSide PROBING PROTEINS A numerical look to www.wellcome.ac.uk/bigpicture/ proteins for more teaching resources, including extra articles, useful. Mitochondrion Human egg Globular protein Uk argentina Bangladesh in human proteins are essential

Rambaut, Andrew

347

Contact List, Human Resources  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Human Resources & Occupational Medicine Division Human Resources & Occupational Medicine Division Contact List Human Resources Guest, User, Visitor (GUV) Center Occupational Medicine Training and Qualifications Office Note: All listed phone extensions are in the format of (631) 344-xxxx. Human Resources Robert Lincoln, Chief Human Resources Officer x7435 rlincoln@bnl.gov Margaret Hughes x2108 hughes@bnl.gov Elizabeth Gilbert x2315 gilbert@bnl.gov Human Resources Generalists Christel Colon, HR Manager - BES, GARS & ELS x8469 ccolon@bnl.gov Joann Williams, HR Manager - Support Operations x8356 williamsj@bnl.gov Joanna Hall, HR Manager - Photon Sciences x4410 jhall@bnl.gov Donna Dowling, HR Manager - Nuclear & Particle Physics x2754 dowling@bnl.gov Terrence Buck x8715 tbuck@bnl.gov

348

Generation of a suite of 3D computer-generated breast phantoms from a limited set of human subject data  

SciTech Connect (OSTI)

Purpose: The authors previously reported on a three-dimensional computer-generated breast phantom, based on empirical human image data, including a realistic finite-element based compression model that was capable of simulating multimodality imaging data. The computerized breast phantoms are a hybrid of two phantom generation techniques, combining empirical breast CT (bCT) data with flexible computer graphics techniques. However, to date, these phantoms have been based on single human subjects. In this paper, the authors report on a new method to generate multiple phantoms, simulating additional subjects from the limited set of original dedicated breast CT data. The authors developed an image morphing technique to construct new phantoms by gradually transitioning between two human subject datasets, with the potential to generate hundreds of additional pseudoindependent phantoms from the limited bCT cases. The authors conducted a preliminary subjective assessment with a limited number of observers (n= 4) to illustrate how realistic the simulated images generated with the pseudoindependent phantoms appeared. Methods: Several mesh-based geometric transformations were developed to generate distorted breast datasets from the original human subject data. Segmented bCT data from two different human subjects were used as the 'base' and 'target' for morphing. Several combinations of transformations were applied to morph between the 'base' and 'target' datasets such as changing the breast shape, rotating the glandular data, and changing the distribution of the glandular tissue. Following the morphing, regions of skin and fat were assigned to the morphed dataset in order to appropriately assign mechanical properties during the compression simulation. The resulting morphed breast was compressed using a finite element algorithm and simulated mammograms were generated using techniques described previously. Sixty-two simulated mammograms, generated from morphing three human subject datasets, were used in a preliminary observer evaluation where four board certified breast radiologists with varying amounts of experience ranked the level of realism (from 1 ='fake' to 10 ='real') of the simulated images. Results: The morphing technique was able to successfully generate new and unique morphed datasets from the original human subject data. The radiologists evaluated the realism of simulated mammograms generated from the morphed and unmorphed human subject datasets and scored the realism with an average ranking of 5.87 {+-} 1.99, confirming that overall the phantom image datasets appeared more 'real' than 'fake.' Moreover, there was not a significant difference (p > 0.1) between the realism of the unmorphed datasets (6.0 {+-} 1.95) compared to the morphed datasets (5.86 {+-} 1.99). Three of the four observers had overall average rankings of 6.89 {+-} 0.89, 6.9 {+-} 1.24, 6.76 {+-} 1.22, whereas the fourth observer ranked them noticeably lower at 2.94 {+-} 0.7. Conclusions: This work presents a technique that can be used to generate a suite of realistic computerized breast phantoms from a limited number of human subjects. This suite of flexible breast phantoms can be used for multimodality imaging research to provide a known truth while concurrently producing realistic simulated imaging data.

Hsu, Christina M. L. [Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708 and Carl E. Ravin Advanced Imaging Laboratories, Duke University Medical Center, Durham, North Carolina 27705 (United States); Palmeri, Mark L. [Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708 (United States); Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710 (United States); Segars, W. Paul [Carl E. Ravin Advanced Imaging Laboratories, Duke University Medical Center, Durham, North Carolina 27705 (United States); Department of Radiology, Duke University Medical Center, Durham, North Carolina 27710 (United States); Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708 (United States); Medical Physics Graduate Program, Duke University, Durham, North Carolina 27705 (United States); Veress, Alexander I. [Department of Mechanical Engineering, University of Washington, Seattle, Washington 98195 (United States); Dobbins, James T. III [Carl E. Ravin Advanced Imaging Laboratories, Duke University Medical Center, Durham, North Carolina 27705 (United States); Department of Radiology, Duke University Medical Center, Durham, North Carolina 27710 (United States); Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708 (United States); Medical Physics Graduate Program, Duke University, Durham, North Carolina 27705 (United States); Department of Physics, Duke University, Durham, North Carolina 27708 (United States)

2013-04-15T23:59:59.000Z

349

ORISE: Protecting Human Subjects  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

or performed by DOE employees, addresses the protection of human subjects. The Oak Ridge Institute for Science and Education (ORISE) supports DOE in its efforts to protect...

350

EMSL - human health  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

human-health en Physical Properties of Ambient and Laboratory-Generated Secondary Organic Aerosol. http:www.emsl.pnl.govemslwebpublicationsphysical-properties-ambient-and-labo...

351

The neutron skin in neutron-rich nuclei at Jefferson Lab  

SciTech Connect (OSTI)

The Jefferson Lab program to measure the symmetry energy of neutron-rich nuclear matter, using precision electroweak methods, is progressing well. The initial measurement by the PREX experiment, leading to a 2-sigma determination of the "neutron skin" in {sup 208}Pb , has been published. Design and preparation for a further, more-precise measurement on {sup 208}Pb is progressing well and there is general acceptance of the great advantage to a further measurement on {sup 48}Ca . The surprising ancillary result that the beam-normal single-spin asymmetry for {sup 208}Pb is consistent with zero is also now in the literature. This paper will discuss the current experimental situation of the program.

Dalton, Mark M. [JLAB

2013-11-01T23:59:59.000Z

352

Analysis of Conductor Impedances Accounting for Skin Effect and Nonlinear Permeability  

SciTech Connect (OSTI)

It is often necessary to protect sensitive electrical equipment from pulsed electric and magnetic fields. To accomplish this electromagnetic shielding structures similar to Faraday Cages are often implemented. If the equipment is inside a facility that has been reinforced with rebar, the rebar can be used as part of a lighting protection system. Unfortunately, such shields are not perfect and allow electromagnetic fields to be created inside due to discontinuities in the structure, penetrations, and finite conductivity of the shield. In order to perform an analysis of such a structure it is important to first determine the effect of the finite impedance of the conductors used in the shield. In this paper we will discuss the impedances of different cylindrical conductors in the time domain. For a time varying pulse the currents created in the conductor will have different spectral components, which will affect the current density due to skin effects. Many construction materials use iron and different types of steels that have a nonlinear permeability. The nonlinear material can have an effect on the impedance of the conductor depending on the B-H curve. Although closed form solutions exist for the impedances of cylindrical conductors made of linear materials, computational techniques are needed for nonlinear materials. Simulations of such impedances are often technically challenging due to the need for a computational mesh to be able to resolve the skin depths for the different spectral components in the pulse. The results of such simulations in the time domain will be shown and used to determine the impedances of cylindrical conductors for lightning current pulses that have low frequency content.

Perkins, M P; Ong, M M; Brown, C G; Speer, R D

2011-07-20T23:59:59.000Z

353

Effect of dietary polyunsaturated fatty acids and related nutrients on sebum lipids, and skin and hair coat condition in canines  

E-Print Network [OSTI]

A study was performed to investigate the effect of diets rich in polyunsaturated fatty acids and other related nutrients, in the effort to improve skin and hair coat conditions in canines. The study included 24 dogs fed a baseline diet (Ol...

Kirby, Naomi Anne

2005-02-17T23:59:59.000Z

354

Safety and Efficacy of Dose-Intensive Oral Vitamin A in Subjects with Sun-Damaged Skin  

Science Journals Connector (OSTI)

...question When out in the sun for two hours or more...protect your skin from sun with clothes or sunscreen...were assigned to 0. The distribution of this score was then...where indicates greater sun exposure (12). Vitamin...allowed to clot at room temperature, and then were centrifuged...

David Alberts; James Ranger-Moore; Janine Einspahr; Kathylynn Saboda; Paul Bozzo; Yun Liu; Xiao-chun Xu; Reuben Lotan; James Warneke; Stuart Salasche; Suzanne Stratton; Norman Levine; Rayna Goldman; Marcy Islas; Laura Duckett; Deborah Thompson; and Peter Bartels

2004-03-15T23:59:59.000Z

355

Surface Zwitterionization of Expanded Poly(tetrafluoroethylene) Membranes via Atmospheric Plasma-Induced Polymerization for Enhanced Skin Wound Healing  

Science Journals Connector (OSTI)

Surface Zwitterionization of Expanded Poly(tetrafluoroethylene) Membranes via Atmospheric Plasma-Induced Polymerization for Enhanced Skin Wound Healing ... Incubation of cell suspension with the samples was performed at 37 °C in a humidified atmosphere of 5% CO2 and for 24 h. ...

Jheng-Fong Jhong; Antoine Venault; Chun-Chung Hou; Sheng-Han Chen; Ta-Chin Wei; Jie Zheng; James Huang; Yung Chang

2013-06-24T23:59:59.000Z

356

Landau damping and anomalous skin effect in low-pressure gas discharges: Self-consistent treatment of collisionless heatinga...  

E-Print Network [OSTI]

for calculation of the non-Maxwellian EEDF. This system was applied to the calculation of collisionless heating electric field anomalous skin effect . Also for inhomogeneous electric fields another mechanism of heating density profile and a Maxwellian EEDF. In the present study a self-consistent system of equations

Kaganovich, Igor

357

Inhibition of 9,10-Dimethyl-1,2-benzanthracene Skin Carcinogenesis in Mice by Polycyclic Hydrocarbons  

Science Journals Connector (OSTI)

...tested for their power to de lay or to...Milling Co.) and water ad libitum. Twenty...2-benzanthracene Skin Car cinogenesis in...the inhibitory power of other substances, including potent car cinogens, are...of its promoting power. If this is true...capacities of the car cinogen, while...

Willard T. Hill; D. Warren Stanger; Anthony Pizzo; Byron Riegel; Philippe Shubik; and William B. Wartman

1951-11-01T23:59:59.000Z

358

Effects of Chronic Low-Dose Ultraviolet B Radiation on DNA Damage and Repair in Mouse Skin  

Science Journals Connector (OSTI)

...of mammalian skin to solar UVB. We analyzed DNA...significantly less repair capacity than rapidly dividing...the loss of this repair capacity could partially contribute...in excision-repair capacity, and potentiation of...low-dose exposure to solar UVB may result in a significant...

David L. Mitchell; Rüdiger Greinert; Frank R. de Gruijl; Kees L. H. Guikers; Eckhard W. Breitbart; Michelle Byrom; Michelle M. Gallmeier; Megan G. Lowery; and Beate Volkmer

1999-06-15T23:59:59.000Z

359

Proper Setup of HVAC System in Conjunction with Sound Building 'Skin' Design for Alleviation of IAQ and Energy Performance Problems  

E-Print Network [OSTI]

climates, not only because of the loss of energy, but also because of damage that can result to insulation, drywall, and structure in addition to promotion of mold and mildew growth. Proper setup of the HVAC system, in conjunction with sound building “skin...

Rosenberg, M.

2006-01-01T23:59:59.000Z

360

Chapter 10 - The Use of Natural Compounds and Botanicals in the Development of Anti-Aging Skin Care Products  

Science Journals Connector (OSTI)

Publisher Summary This chapter discusses the evidence for the application of botanicals and natural products to modulate several of these targets, namely, oxidation, inflammation, the skin barrier, the extracellular matrix (ECM), and DNA repair. Cosmetic formulations have been based on botanical ingredients since ancient times, and botanical and natural extracts maintain a major role in contemporary cosmetics. Present means of treating aging skin have become more technological and more invasive; however, natural products including botanicals are still relevant and can be highly efficacious. Scientific research continues to corroborate traditional uses of many plants for skin benefits, and to elucidate biochemical mechanisms of action for a growing number of phytochemicals. Additional clinical trials are necessary to optimize the application of natural ingredients for cosmetics, but scientific substantiation for the safety and efficacy of a host of botanical extracts and compounds for treating aging skin is evident, with the continued potential of many more. It is highly unlikely that science will ever identify all of the active compounds in a given plant, but it is equally unlikely that one will stop finding new activities in plants that have relevance to healthier aging. The main barrier to continued discovery might indeed be the accelerating loss of biodiversity on the planet.

Cindy K. Angerhofer; Daniel Maes; Paolo U. Giacomoni

2009-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "human skin model" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


361

Viscoelastic Analysis of Sandwich Beams Having Aluminum and Fiber-reinforced Polymer Skins with a Polystyrene Foam Core  

E-Print Network [OSTI]

Sandwich beams are composite systems having high stiffness-to-weight and strength-to-weight ratios and are used as light weight load bearing components. The use of thin, strong skin sheets adhered to thicker, lightweight core materials has allowed...

Roberts-Tompkins, Altramese L.

2010-07-14T23:59:59.000Z

362

Science and Human Values  

Science Journals Connector (OSTI)

... THE three essays on "Science and Human A Values" which Dr. J. Bronowski has contributed to recent issues ... Dr. Bronowski discusses the sense of human dignity and challenges widely held views of what science is and does. These views are highly relevant to the current task of developing- ...

1957-02-02T23:59:59.000Z

363

integration division Human Systems  

E-Print Network [OSTI]

Vibration Test Facility incorporates state-of-the-art vibration generation and measurement hardwareintegration division Human Systems ISIS Vibration Test Facility Objective Approach Impact 1. Assess impact of flight-like whole-body vibration on human operational capabilities and ability to maintain

364

STUDENT EMPLOYMENT HUMAN RESOURCES  

E-Print Network [OSTI]

STUDENT EMPLOYMENT HUMAN RESOURCES GUIDELINE Human Resources | One Washington Square | San José, CA 95192-0046 | 408-924-2250 408-924-2284 (fax) SUBJECT: STUDENT EMPLOYMENT DATE: March 2007 I. PURPOSE / DESCRIPTION Student employees are defined as matriculated students that work part-time in any

Gleixner, Stacy

365

Human Functional Brain Imaging  

E-Print Network [OSTI]

Human Functional Brain Imaging 1990­2009 September 2011 Portfolio Review Summary Brain Imaging #12 Dale ­ one of our first Trustees. Understanding the brain remains one of our key strategic aims today three-fold: · to identify the key landmarks and influences on the human functional brain imaging

Rambaut, Andrew

366

Protection of Human Subjects  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

The order establishes Department of Energy (DOE) procedures and responsibilities for implementing the policy and requirements set forth in 10 Code of Federal Regulations (CFR) Part 745, Protection of Human Subjects; and in DOE P 443.1A, Protection of Human Subjects, dated 12-20-07. Cancels DOE O 443.1. Canceled by DOE O 443.1B.

2007-12-20T23:59:59.000Z

367

Protection of Human Subjects  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

To establish DOE procedures and responsibilities for implementing the policy and requirements set forth in 10 CFR Part 745, Protection of Human Subjects, ad in DOE P 443.1, Policy on the Protection of Human Subjects. Cancels DOE O 1300.3. Canceled by DOE O 443.1A.

2000-05-15T23:59:59.000Z

368

Thermodynamics and Humanism  

Science Journals Connector (OSTI)

... chapter, his intention appears to have been to write on the wider human aspects of thermodynamics, to contribute to scientific humanism, which he defines as the unification of the specialized ... body of the book is, however, a fairly straightforward explanation of the laws of thermodynamics, partly classical and partly statistical, which will undoubtedly be helpful to students of the ...

J. A. V. BUTLER

1947-07-19T23:59:59.000Z

369

Genomics of human longevity  

Science Journals Connector (OSTI)

...the original work is properly cited. Genomics of human longevity P. E. Slagboom 1...progress. human longevity|longevity genomics|epigenetics and ageing| 1. Introduction...Innovation Oriented Research Programme on Genomics (SenterNovem; IGE01014 and IGE5007...

2011-01-01T23:59:59.000Z

370

Humans and Gills  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Humans and Gills Humans and Gills Name: Shelley Location: N/A Country: N/A Date: N/A Question: Is it true that some babies are born with some sort of gills? How and when do humans adapt from breathing inside to breathing outside of the womb? Replies: Whoa! You have received a great deal of false information. First, babies are not born with gills! Get that out of your thinking! Babies do not "breath" for oxygen in the womb. They do "practice breathing" using the amniotic fluid of the womb, but it is not doing them any good otherwise. All of the embryo and fetal needs are received through the placenta. The mother provides everything that is needed. As for the gills, there is a stage in the early human embryo development whereby humans do show gill slits, but not functional gills. Slits are not gills!! As a matter of fact, all vertebrates show these same gill slits.

371

A lumped-parameter electro-thermal model for cylindrical batteries Xinfan Lin a,*, Hector E. Perez a  

E-Print Network [OSTI]

A lumped-parameter electro-thermal model for cylindrical batteries Xinfan Lin a,*, Hector E. Perez i g h t s An electro-thermal model capturing battery SOC, voltage, skin and core temperature: Lithium ion batteries Electro-thermal model Parameterization Core temperature State of charge a b s t r

Stefanopoulou, Anna

372

Finite element decomposition of the human neocortex  

E-Print Network [OSTI]

. . . . . . . . . . . . . . . . . . . . . ?. .. . , . . . . . C. Application of Software Tools to the Human Neocortex. . . . . . . . 72 . . . . 72 . . . . 74 VIII RESULTS. . . . . 77 A. B. C. D. E. F. Contour Extraction . , Solid Model Reconstruction of the Right Hemisphere. . . . Extraction.... Summary. B. Future Work. . . . . . 101 . . . . . 101 REFERENCES. , . . . . . 105 . . . . . 110 LIST OF FIGURES FIGURE Page 1 Reconstruction stages. . . . . . 2 Voronoi diagram and Delaunay triangulation . . . . . 13 3 IVS and EVS of two contours...

Chow, Seeling

2012-06-07T23:59:59.000Z

373

Exploring Paradigms of Human Resource Development  

E-Print Network [OSTI]

This study focused on the issue of paradigms in Human Resource Development (HRD). Its purpose was to validate the HRD Cube as a synthesized model of HRD and to explicate some of the extant paradigms of HRD. The study was carried out by examining...

Hurt, Andrew Christopher

2011-10-21T23:59:59.000Z

374

Giant Tunneling Piezoresistance of Composite Elastomers with Interlocked Microdome Arrays for Ultrasensitive and Multimodal Electronic Skins  

Science Journals Connector (OSTI)

The solid lines represent power-law fits to ACNT with an exponent of 0.7. ... This real-time monitoring capability can also be used to monitor human motion, for example, finger-bending motion (Figure 3d). ... Multifunctional capability, flexible design, rugged lightweight construction and self-powered operation are desired attributes for electronics that directly interface with the human body or with advanced robotic systems. ...

Jonghwa Park; Youngoh Lee; Jaehyung Hong; Minjeong Ha; Young-Do Jung; Hyuneui Lim; Sung Youb Kim; Hyunhyub Ko

2014-03-04T23:59:59.000Z

375

Biosphere Model Report  

SciTech Connect (OSTI)

The purpose of this report is to document the biosphere model, the Environmental Radiation Model for Yucca Mountain, Nevada (ERMYN), which describes radionuclide transport processes in the biosphere and associated human exposure that may arise as the result of radionuclide release from the geologic repository at Yucca Mountain. The biosphere model is one of the process models that support the Yucca Mountain Project (YMP) Total System Performance Assessment (TSPA) for the license application (LA), TSPA-LA. The ERMYN provides the capability of performing human radiation dose assessments. This report documents the biosphere model, which includes: (1) Describing the reference biosphere, human receptor, exposure scenarios, and primary radionuclides for each exposure scenario (Section 6.1); (2) Developing a biosphere conceptual model using site-specific features, events, and processes (FEPs) (Section 6.2), the reference biosphere (Section 6.1.1), the human receptor (Section 6.1.2), and approximations (Sections 6.3.1.4 and 6.3.2.4); (3) Building a mathematical model using the biosphere conceptual model (Section 6.3) and published biosphere models (Sections 6.4 and 6.5); (4) Summarizing input parameters for the mathematical model, including the uncertainty associated with input values (Section 6.6); (5) Identifying improvements in the ERMYN compared with the model used in previous biosphere modeling (Section 6.7); (6) Constructing an ERMYN implementation tool (model) based on the biosphere mathematical model using GoldSim stochastic simulation software (Sections 6.8 and 6.9); (7) Verifying the ERMYN by comparing output from the software with hand calculations to ensure that the GoldSim implementation is correct (Section 6.10); (8) Validating the ERMYN by corroborating it with published biosphere models; comparing conceptual models, mathematical models, and numerical results (Section 7).

D.W. Wu; A.J. Smith

2004-11-08T23:59:59.000Z

376

Combining Skeletal Pose with Local Motion for Human Activity Recognition  

E-Print Network [OSTI]

challenge in modeling and inferring articulated human motion from video. However, recent developments on the dynamic poses. We demonstrate the representative power of dynamic pose over raw skeletal pose. Our results conclusively demonstrate that dynamic pose is a more powerful representation of human

Corso, Jason J.

377

Division of Human Resources Human Resources / Attendance and Leave Philosophy  

E-Print Network [OSTI]

Division of Human Resources PHILOSOPHY Human Resources / Attendance and Leave Philosophy Form Leave Act (FMLA). USF augments these provisions with local processes and philosophies and, in some cases

Meyers, Steven D.

378

The human genome project  

SciTech Connect (OSTI)

The Human Genome Project will obtain high-resolution genetic and physical maps of each human chromosome and, somewhat later, of the complete nucleotide sequence of the deoxyribonucleic acid (DNA) in a human cell. The talk will begin with an extended introduction to explain the Project to nonbiologists and to show that map construction and sequence determination require extensive computation in order to determine the correct order of the mapped entities and to provide estimates of uncertainty. Computational analysis of the sequence data will become an increasingly important part of the project, and some computational challenges are described. 5 refs.

Bell, G.I.

1991-06-01T23:59:59.000Z

379

Transformation of human melanocytes and mechanisms of melanoma metastasis  

E-Print Network [OSTI]

While a fundamental feature of human melanoma is its tendency to metastasize to numerous organs throughout the body, very few animal models recapitulate this essential aspect of the disease. In the work described, it is ...

Gupta, Piyush B

2006-01-01T23:59:59.000Z

380

Genomic and Genetic Definition of a Functional Human Centromere  

Science Journals Connector (OSTI)

...Artificial, Human Computer Simulation Contig...1 and 3) (32). Computer modeling of unequal crossover as a mechanism...multimeric repeat units and the rapid fall in sequence...analysis of signature sites was automated using a perl script, modifying...

Mary G. Schueler; Anne W. Higgins; M. Katharine Rudd; Karen Gustashaw; Huntington F. Willard

2001-10-05T23:59:59.000Z

Note: This page contains sample records for the topic "human skin model" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


381

A Computational Study of the Deacylation Mechanism of Human Butyrylcholinesterase  

Science Journals Connector (OSTI)

To investigate the mechanism of the deacylation reaction in the active site of human butyrylcholinesterase (BuChE), we carried out quantum mechanical (QM) calculations on cluster models of the active site built from a crystallographic structure. The ...

Dimas Suárez; Natalia Díaz; Juan Fontecilla-Camps; Martin J. Field

2006-05-19T23:59:59.000Z

382

Unpublished Document Stefan Brandle 1996 ACKNOWLEDGMENTS IN HUMAN TUTORING SESSIONS  

E-Print Network [OSTI]

Unpublished Document © Stefan Brandle 1996 ACKNOWLEDGMENTS IN HUMAN TUTORING SESSIONS Document © Stefan Brandle 1996 ii TABLE OF CONTENTS CHAPTER I. INTRODUCTION Language Interfaces . 42 6.3 Modify Student Model for Higher Resolution Tracking . . . . . 43 #12

383

Algorithms for simulating human pre-mRNA splicing decisions  

E-Print Network [OSTI]

In this thesis, I developed a program, ExonScan, to simulate constitutive human pre-mRNA splicing. ExonScan includes several models for splicing components, including splice sites, exonic splicing enhancers, exonic splicing ...

Rolish, Michael E. (Michael Edward)

2005-01-01T23:59:59.000Z

384

Spontaneous Human Combustion  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Spontaneous Human Combustion Spontaneous Human Combustion Name: S. Phillips. Age: N/A Location: N/A Country: N/A Date: N/A Question: One of our 8th grade students has tried to find information in our library about spontaneous human combustion, but to no avail. Could you tell us where we might locate a simple reference, or provide some in information about this subject for him. Replies: Sorry, but this is definitely "fringe science"...try asking in bookstores. I seem to recall one of those "believe it or not" type of TV shows did an episode on spontaneous human combustion a few years ago in which they reported on some British scientists who investigated this purported phenomenon. Remember that people (back in the Dark Ages, and before) used to believe in "spontaneous generation" of certain plants and animals because they were not aware of the reproduction methods used by those plants and animals.

385

TEMPORARY SUPPORT HUMAN RESOURCES  

E-Print Network [OSTI]

TEMPORARY SUPPORT HUMAN RESOURCES GUIDELINE Workforce Planning | One Washington Square | San José of the Request for Temporary Support, Workforce Planning will make a determination of the type of temporary

Su, Xiao

386

Human intelligible positioning  

E-Print Network [OSTI]

We use street addresses to refer to locations in a city. Street addresses are easy to remember and communicate because they follow a symbolic addressing scheme, containing human intelligible symbols. However, street addresses ...

Venugopalan, Vishwanath, 1981-

2004-01-01T23:59:59.000Z

387

KRFTWRK – Global Human Electricity  

E-Print Network [OSTI]

Power Network 2.1.1 Virtual Power Plants The Global Powernetwork, based on "Virtual Power Plants", called "VPP". A "participant runs a virtual human power plant. Per every "

Prohaska, Rainer

2009-01-01T23:59:59.000Z

388

Human Reliability Program Overview  

SciTech Connect (OSTI)

This presentation covers the high points of the Human Reliability Program, including certification/decertification, critical positions, due process, organizational structure, program components, personnel security, an overview of the US DOE reliability program, retirees and academia, and security program integration.

Bodin, Michael

2012-09-25T23:59:59.000Z

389

Humans Need Biodiversity  

Science Journals Connector (OSTI)

...economic, and environmental policies—the three pillars of sustainability practice—to manage natural resource...bright light on the tight connections between sustainability practices and human survival could make conservation...

David P. Mindell

2009-03-20T23:59:59.000Z

390

Human Resource Management Delegation  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

The notice is to clarifies and updates existing Human Resource Management Delegation Authorities and the levels to which they are delegated. Expired 6-28-97. Does not cancel any directives.

1996-06-28T23:59:59.000Z

391

Human Resources & Rebecca Leinen  

E-Print Network [OSTI]

Human Resources & Training Rebecca Leinen SafetyInformation Systems Chris Smeds Work Management Mark Webb Energy & Utilities Cheryl Gomez Operations & Maintenance Cheryl Gomez, interim Systems Services Delta Force Recycling Sustainability Outreach Office for Sustainability Utility Systems Power

Acton, Scott

392

Protection of Human Subjects  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

The purpose of this Policy is to establish DOE-specific policy for the protection of human subjects involved in DOE research. Canceled by DOE P 443.1A.

2000-05-15T23:59:59.000Z

393

Protection of Human Subjects  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

The Policy is to establish DOE-specific principles for the protection of human subjects involved in DOE research. Cancels DOE P 443.1. Canceled by DOE O 443.1B

2007-12-20T23:59:59.000Z

394

Human errors and structural failure probability  

Science Journals Connector (OSTI)

Predicting the influence of human errors on structural failure probability is the topic of this paper. There are two principal reasons for needing this information. First, if errors are present after the design of a structure is completed, as is generally the case, this will provide the engineer with a measure of what effect such errors will have on the structural safety. Second, this information is directly useful in the optimisation of quality assurance expenditures, which can effectively be used for controlling the probability of structural failure due to errors. Simplified probabilistic models are developed to integrate human errors into structural risk assessment. Numerical examples illustrate the sensitivity of structural safety to errors.

Dan M. Frangopol

1988-01-01T23:59:59.000Z

395

Human Factors Review Plan  

SciTech Connect (OSTI)

''Human Factors'' is concerned with the incorporation of human user considerations into a system in order to maximize human reliability and reduce errors. This Review Plan is intended to assist in the assessment of human factors conditions in existing DOE facilities. In addition to specifying assessment methodologies, the plan describes techniques for improving conditions which are found to not adequately support reliable human performance. The following topics are addressed: (1) selection of areas for review describes techniques for needs assessment to assist in selecting and prioritizing areas for review; (2) human factors engineering review is concerned with optimizing the interfaces between people and equipment and people and their work environment; (3) procedures review evaluates completeness and accuracy of procedures, as well as their usability and management; (4) organizational interface review is concerned with communication and coordination between all levels of an organization; and (5) training review evaluates training program criteria such as those involving: trainee selection, qualification of training staff, content and conduct of training, requalification training, and program management.

Paramore, B.; Peterson, L.R. (eds.)

1985-12-01T23:59:59.000Z

396

E-Print Network 3.0 - anti-fya seraclone human Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

presented. Sphere-based geometric models... are used for the human and robot due to the efficiency of the distance computation. The collision avoidance Source: Bone, Gary -...

397

E-Print Network 3.0 - antimicrobial peptide human Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

and Antimicrobial Properties by a Rational Prediction Model Summary: -Reyes SO, Teran LM (2010) Antimicrobial peptides: general overview and clinical implications in human......

398

Vision application of human robot interaction: Development of a ping pong playing robotic arm.  

E-Print Network [OSTI]

?? Robotics is a science that is implemented parallel to human behavior. This work describes and implements techniques to mathematically model the game of ping… (more)

Modi, Kalpesh Prakash

2005-01-01T23:59:59.000Z

399

E-Print Network 3.0 - atm radiosensitizes human Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

and Medicine 3 Journal of Theoretical Biology 230 (2004) 120 A four-dimensional simulation model of tumour response to Summary: The intrinsic radiosensitivity of human tumour...

400

The Human Genome From human genome to other  

E-Print Network [OSTI]

genome to health Structural Genomics initiative #12;What is the Human Genome Project? · U.S. govtThe Human Genome Project From human genome to other genomes and to gene function June 2000 From that arise from genome research #12;The Human Genome Project Project began in 1990 as a $3 billion, 15-year

Linial, Michal

Note: This page contains sample records for the topic "human skin model" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


401

Coordination-resolved local bond contraction and electron binding-energy entrapment of Si atomic clusters and solid skins  

SciTech Connect (OSTI)

Consistency between x-ray photoelectron spectroscopy measurements and density-function theory calculations confirms our bond order-length-strength notation-incorporated tight-binding theory predictions on the quantum entrapment of Si solid skin and atomic clusters. It has been revealed that bond-order deficiency shortens and strengthens the Si-Si bond, which results in the local densification and quantum entrapment of the core and valence electrons. Unifying Si clusters and Si(001) and (111) skins, this mechanism has led to quantification of the 2p binding energy of 96.089?eV for an isolated Si atom, and their bulk shifts of 2.461?eV. Findings evidence the significance of atomic undercoordination that is of great importance to device performance.

Bo, Maolin; Huang, Yongli; Zhang, Ting [Key Laboratory of Low-Dimensional Materials and Application Technologies, Xiangtan University, Hunan 411105 (China); Wang, Yan, E-mail: ywang8@hnust.edu.cn, E-mail: ecqsun@ntu.edu.sg [Key Laboratory of Low-Dimensional Materials and Application Technologies, Xiangtan University, Hunan 411105 (China); School of Information and Electronic Engineering, Hunan University of Science and Technology, Hunan 411201 (China); Zhang, Xi [School of Electrical and Electronic Engineering, Nanyang Technological University, Singapore 639798 (Singapore); Li, Can [Center for Coordination Bond Engineering, School of Materials Science and Engineering, China Jiliang University, Hangzhou 330018 (China); Sun, Chang Q., E-mail: ywang8@hnust.edu.cn, E-mail: ecqsun@ntu.edu.sg [Key Laboratory of Low-Dimensional Materials and Application Technologies, Xiangtan University, Hunan 411105 (China); School of Electrical and Electronic Engineering, Nanyang Technological University, Singapore 639798 (Singapore); Center for Coordination Bond Engineering, School of Materials Science and Engineering, China Jiliang University, Hangzhou 330018 (China)

2014-04-14T23:59:59.000Z

402

Use of Axillary Deodorant and Effect on Acute Skin Toxicity During Radiotherapy for Breast Cancer: A Prospective Randomized Noninferiority Trial  

SciTech Connect (OSTI)

Purpose: To prospectively determine the effect of deodorant use on acute skin toxicity and quality of life during breast radiotherapy (RT). Methods and Materials: Before breast RT, 84 patients were randomly assigned to the deodorant group (n = 40) or the no-deodorant group (n = 44). The patients were stratified by axillary RT and previous chemotherapy. Toxicity evaluations were always performed by the principal investigator, who was unaware of the group assignment, at the end of RT and 2 weeks after completion using the Radiation Therapy Oncology Group acute skin toxicity criteria. Symptoms of acute skin toxicity (i.e., discomfort, pain, pruritus, sweating) and quality of life were self-evaluated. For each criterion, the point estimate of rate difference with the 95% one-sided upper confidence limit was computed. To claim noninferiority owing to deodorant use, the 95% one-sided upper confidence limit had to be lower than the noninferiority margin, fixed to 12.8%. Results: In the deodorant vs. no-deodorant groups, Grade 2 axillary radiodermatitis occurred in 23% vs. 30%, respectively, satisfying the statistical criteria for noninferiority (p = .019). Grade 2 breast radiodermatitis occurred in 30% vs. 34% of the deodorant vs. no-deodorant groups, respectively, also satisfying the statistical criteria for noninferiority (p = .049). Similar results were observed for the self-reported evaluations. The deodorant group reported less sweating (18% vs. 39%, p = .032). No Grade 3 or 4 radiodermatitis was observed. Conclusion: According to our noninferiority margin definition, the occurrence of skin toxicity and its related symptoms were statistically equivalent in both groups. No evidence was found to prohibit deodorant use (notwithstanding the use of an antiperspirant with aluminum) during RT for breast cancer.

Theberge, Valerie, E-mail: valerie.theberge.1@ulaval.c [Departement de Radio-Oncologie, L'Hotel-Dieu de Quebec, Centre Hospitalier Universitaire de Quebec, Quebec, QB (Canada); Harel, Francois [Centre de Recherche de L'Hotel-Dieu de Quebec, L'Hotel-Dieu de Quebec, Centre Hospitalier Universitaire de Quebec, Centre de Recherche en Cancerologie de l'Universite Laval, Quebec, QB (Canada); Dagnault, Anne [Departement de Radio-Oncologie, L'Hotel-Dieu de Quebec, Centre Hospitalier Universitaire de Quebec, Quebec, QB (Canada); Centre de Recherche de L'Hotel-Dieu de Quebec, L'Hotel-Dieu de Quebec, Centre Hospitalier Universitaire de Quebec, Centre de Recherche en Cancerologie de l'Universite Laval, Quebec, QB (Canada)

2009-11-15T23:59:59.000Z

403

Locoregional Outcomes of Inflammatory Breast Cancer Patients Treated With Standard Fractionation Radiation and Daily Skin Bolus in the Taxane Era  

SciTech Connect (OSTI)

Purpose: To assess locoregional outcomes of inflammatory breast cancer (IBC) patients who received standard fractionation radiation with daily skin bolus and taxanes as part of combined-modality therapy (CMT). Methods and Materials: We retrospectively reviewed the charts of 107 patients diagnosed with IBC between January 1995 and March 2006 who presented to our department for adjuvant radiation therapy (RT). Results: All patients received chemotherapy (95% anthracycline and 95% taxane), modified radical mastectomy, and RT to the chest wall and regional lymphatics using standard fractionation to 50 Gy and daily skin bolus. The RT to the chest wall was delivered via electrons (55%) or photons (45%) in daily fractions of 180 cGy (73%) or 200 cGy (27%). Scar boost was performed in 11%. A majority (84%) of patients completed the prescribed treatment. Median follow-up was 47 months (range, 10-134 months). Locoregional control (LRC) at 3 years and 5 years was 90% and 87%, respectively. Distant metastases-free survival (DMFS) at 3 years and 5 years was 61% and 47%, respectively. Conclusions: Excellent locoregional control was observed in this population of IBC patients who received standard fractionation radiation with daily skin bolus and taxanes as part of combined-modality therapy. Distant metastases-free survival remains a significant therapeutic challenge.

Damast, Shari, E-mail: damasts@mskcc.or [Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY (United States); Ho, Alice Y. [Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY (United States); Montgomery, Leslie [Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY (United States); Fornier, Monica N. [Department of Breast Cancer Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY (United States); Ishill, Nicole; Elkin, Elena [Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY (United States); Beal, Kathryn; McCormick, Beryl [Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY (United States)

2010-07-15T23:59:59.000Z

404

Time, Humans and Societal Challenges  

E-Print Network [OSTI]

,000 (human development) Since 1850 (industrial revolution Since 1950 (population explosion) Sustainable

405

Neutron radii and the neutron equation of state in relativistic models  

Science Journals Connector (OSTI)

The root-mean-square radii for neutrons in nuclei and their relationship to the neutron equation of state are investigated in the relativistic Hartree model. A correlation between the neutron skin in heavy nuclei and the derivative of the neutron equation of state is found which provides a linear continuation of results obtained from nonrelativistic Hartree-Fock models. The relativistic models tend to give larger neutron radii and an associated stiffer neutron equation of state compared with the nonrelativistic models.

S. Typel and B. Alex Brown

2001-06-29T23:59:59.000Z

406

Postdoctoral Positions in Computational Human Microbiome Research (The Department of Genome Sciences, University of Washington)  

E-Print Network [OSTI]

Postdoctoral Positions in Computational Human Microbiome Research (The Department of Genome funded projects: 1) Computational modeling of the human microbiome using a combination of in://elbo.gs.washington.edu) at the University of Washington. Borenstein's group focuses on computational systems biology research of the human

Borenstein, Elhanan

407

A Consensus Tree Approach for Reconstructing Human Evolutionary History and Detecting  

E-Print Network [OSTI]

genome over time implicitly encodes a history of how human populations have arisen, dispersed of the method on two large-scale genetic variation data sets: the HapMap Phase II and the Human Genome Diversity Project. Qualitative comparison to a consensus model of the evolution of mod- ern human population groups

Ravi, R.

408

New Model to Predict Formation Damage due to Sulfur Deposition in Sour M.A. Mahmoud and A.A. Al-Majed, KFUPM, all SPE  

E-Print Network [OSTI]

porosity, skin damage and reservoir rock wettability. The main objective of this model is to investigate. This model can be used to study the effect of sulfur deposition on gas relative permeability, reservoir model. A reduction of 2000 psi in the reservoir pressure, causes a 40 % loss of reservoir porosity

Al-Majed, Abdulaziz Abdullah

409

Revisiting Low-Dose Total Skin Electron Beam Therapy in Mycosis Fungoides  

SciTech Connect (OSTI)

Purpose: Total skin electron beam therapy (TSEBT) is a highly effective treatment for mycosis fungoides (MF). The standard course consists of 30 to 36 Gy delivered over an 8- to 10-week period. This regimen is time intensive and associated with significant treatment-related toxicities including erythema, desquamation, anhydrosis, alopecia, and xerosis. The aim of this study was to identify a lower dose alternative while retaining a favorable efficacy profile. Methods and Materials: One hundred two MF patients were identified who had been treated with an initial course of low-dose TSEBT (5-<30 Gy) between 1958 and 1995. Patients had a T stage classification of T2 (generalized patch/plaque, n = 51), T3 (tumor, n = 29), and T4 (erythrodermic, n = 22). Those with extracutaneous disease were excluded. Results: Overall response (OR) rates (>50% improvement) were 90% among patients with T2 to T4 disease receiving 5 to <10 Gy (n = 19). In comparison, OR rates between the 10 to <20 Gy and 20 to <30 Gy subgroups were 98% and 97%, respectively. There was no significant difference in median progression free survival (PFS) in T2 and T3 patients when stratified by dose group, and PFS in each was comparable to that of the standard dose. Conclusions: OR rates associated with low-dose TSEBT in the ranges of 10 to <20 Gy and 20 to <30 Gy are comparable to that of the standard dose ({>=} 30 Gy). Efficacy measures including OS, PFS, and RFS are also favorable. Given that the efficacy profile is similar between 10 and <20 Gy and 20 and <30 Gy, the utility of TSEBT within the lower dose range of 10 to <20 Gy merits further investigation, especially in the context of combined modality treatment.

Harrison, Cameron, E-mail: cameronh@stanford.edu [Department of Dermatology, Stanford Cancer Center, Stanford, California (United States); Young, James; Navi, Daniel [Department of Dermatology, Stanford Cancer Center, Stanford, California (United States); Riaz, Nadeem [Department of Radiation Oncology, Stanford Cancer Center, Stanford, California (United States); Lingala, Bharathi; Kim, Youn [Department of Dermatology, Stanford Cancer Center, Stanford, California (United States); Hoppe, Richard [Department of Radiation Oncology, Stanford Cancer Center, Stanford, California (United States)

2011-11-15T23:59:59.000Z

410

Relocation Guide, Human Resources  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Relocation Information Guide Relocation Information Guide The Human Resources Division is providing this Information Guide to you to help ease the transition of relocating to Long Island. Relocating to a new place can be an exciting as well as stressful time. We have compiled information that can be very helpful with the many issues you may face. You may also seek assistance from the recruiter you work with in Human Resources. Service Disclaimer - This web page contains links to other Internet sites. These links are not endorsements of any products or services and no information in such site has been endorsed or approved by Brookhaven National Laboratory or the Human Resources Division. Here are some of the issues: Cost of living Buying or renting a home Schools in the area

411

Turkey vs. human digestion  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Turkey vs. human digestion Turkey vs. human digestion Name: wallyb Location: N/A Country: N/A Date: N/A Question: How is the digestive system of turkeys different from that of humans? Replies: Hmmm.. been a while since I had sophomore biology, so I can't completely answer this one, but I can say a few things. One, since turkeys are birds, and birds as a general rule have not had teeth for several million years at least, the turkey needs a way to mash up its food -- thus, the crop, which is essentially like another stomach: the turkey (and many other birds, for that matter) swallows small stones which serve in lieu of teeth, mashing up food via muscular action in the crop, from whence the "chewed" food moves on into the rest of the digestive tract. As for any other differences, I'll have to leave that to someone else with more ornithological experience...

412

Human MSH2 protein  

DOE Patents [OSTI]

The human MSH2 gene, responsible for hereditary non-polyposis colorectal cancer, was identified by virtue of its homology to the MutS class of genes, which are involved in DNA mismatch repair. The sequence of cDNA clones of the human gene are provided, and the sequence of the gene can be used to demonstrate the existence of germ line mutations in hereditary non-polyposis colorectal cancer (HNPCC) kindreds, as well as in replication error.sup.+ (RER.sup.+) tumor cells.

de la Chapelle, Albert (Helsingfors, FI); Vogelstein, Bert (Baltimore, MD); Kinzler, Kenneth W. (Baltimore, MD)

1997-01-01T23:59:59.000Z

413

Human MSH2 protein  

DOE Patents [OSTI]

The human MSH2 gene, responsible for hereditary non-polyposis colorectal cancer, was identified by virtue of its homology to the MutS class of genes, which are involved in DNA mismatch repair. The sequence of cDNA clones of the human gene are provided, and the sequence of the gene can be used to demonstrate the existence of germ line mutations in hereditary non-polyposis colorectal cancer (HNPCC) kindreds, as well as in replication error{sup +} (RER{sup +}) tumor cells. 19 figs.

Chapelle, A. de la; Vogelstein, B.; Kinzler, K.W.

1997-01-07T23:59:59.000Z

414

Climate and Environmental Sciences Division Strategic Plan Water is a key component of the earth and human  

E-Print Network [OSTI]

, and subsurface processes, as well as climate and earth system modeling and integrated assessment modeling and plan the development of next- generation human-earth system models for improving long-term predictions

Wood, Robert

415

Human Rights and Duties  

Science Journals Connector (OSTI)

... European convention. A draft European convention for the collective protection of individual rights and democratic liberties by member States of the Council of Europe, and for the establishment of a ... accompanied by a recommendation that the whole question of the maintenance of human rights and liberties should be placed upon the agenda of the first session of the European Consultative Assembly ...

1950-01-21T23:59:59.000Z

416

Ubiquitous human computing  

Science Journals Connector (OSTI)

...tomorrow's human one. The Internet faced down proprietary networks...organically the way that the Internet's byways are not owned in...that is in the way the current Internet and its protocols are unowned...significantly different vectors of abuse and control than the one run...

2008-01-01T23:59:59.000Z

417

Ethics, humanity, and science  

Science Journals Connector (OSTI)

Ethics, humanity, and science ... In this issue of the magazine C&EN senior editor Wil Lepkowski, in effect, picks up on this theme with an examination of a debate that may be about to erupt over the methods and ethics of science and scientists, particularly as they apply to the central role of science and technology in the nuclear arms race. ...

MICHEAL HEYLIN

1981-10-05T23:59:59.000Z

418

THE SCIENCE OF HUMANITY  

Science Journals Connector (OSTI)

...one as silver and the other as gold, and have done doughty battle in defense of their one-sided vision; the biol-ogist...peoples, or of human curiosities and monstrosities exhibited in midway plaisances, if nlot in circuses and dime mu-seums. Even...

W J MCGEE

1897-09-17T23:59:59.000Z

419

Crowd modeling and simulation technologies  

Science Journals Connector (OSTI)

As a collective and highly dynamic social group, the human crowd is a fascinating phenomenon that has been frequently studied by experts from various areas. Recently, computer-based modeling and simulation technologies have emerged to support investigation ... Keywords: Crowd simulation, crowd dynamics, human behavior, multi-agent system

Suiping Zhou; Dan Chen; Wentong Cai; Linbo Luo; Malcolm Yoke Hean Low; Feng Tian; Victor Su-Han Tay; Darren Wee Sze Ong; Benjamin D. Hamilton

2010-10-01T23:59:59.000Z

420

Sampling in human cognition  

E-Print Network [OSTI]

Bayesian Decision Theory describes optimal methods for combining sparse, noisy data with prior knowledge to build models of an uncertain world and to use those models to plan actions and make novel decisions. Bayesian ...

Vul, Edward

2010-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "human skin model" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


421

Human sciences The human sciences database contains approximately 254 academic  

E-Print Network [OSTI]

Human sciences The human sciences database contains approximately 254 academic journals and statistical reports on the following subjects: (comparative literature, theology, history and geography, education, psychology, arts, languages and Library Science) Social sciences The social sciences database

422

Human-elephant conflicts; Human-elephant conflicts.  

E-Print Network [OSTI]

?? It is widely recognized that human-wildlife conflicts can reduce farmers’ support for long-term species conservation. The subject of human-elephant conflicts is highly relevant in… (more)

Olsson, Linnea

2014-01-01T23:59:59.000Z

423

Biosphere Process Model Report  

SciTech Connect (OSTI)

To evaluate the postclosure performance of a potential monitored geologic repository at Yucca Mountain, a Total System Performance Assessment (TSPA) will be conducted. Nine Process Model Reports (PMRs), including this document, are being developed to summarize the technical basis for each of the process models supporting the TSPA model. These reports cover the following areas: (1) Integrated Site Model; (2) Unsaturated Zone Flow and Transport; (3) Near Field Environment; (4) Engineered Barrier System Degradation, Flow, and Transport; (5) Waste Package Degradation; (6) Waste Form Degradation; (7) Saturated Zone Flow and Transport; (8) Biosphere; and (9) Disruptive Events. Analysis/Model Reports (AMRs) contain the more detailed technical information used to support TSPA and the PMRs. The AMRs consists of data, analyses, models, software, and supporting documentation that will be used to defend the applicability of each process model for evaluating the postclosure performance of the potential Yucca Mountain repository system. This documentation will ensure the traceability of information from its source through its ultimate use in the TSPA-Site Recommendation (SR) and in the National Environmental Policy Act (NEPA) analysis processes. The objective of the Biosphere PMR is to summarize (1) the development of the biosphere model, and (2) the Biosphere Dose Conversion Factors (BDCFs) developed for use in TSPA. The Biosphere PMR does not present or summarize estimates of potential radiation doses to human receptors. Dose calculations are performed as part of TSPA and will be presented in the TSPA documentation. The biosphere model is a component of the process to evaluate postclosure repository performance and regulatory compliance for a potential monitored geologic repository at Yucca Mountain, Nevada. The biosphere model describes those exposure pathways in the biosphere by which radionuclides released from a potential repository could reach a human receptor. Collectively, the potential human receptor and exposure pathways form the biosphere model. More detailed technical information and data about potential human receptor groups and the characteristics of exposure pathways have been developed in a series of AMRs and Calculation Reports.

J. Schmitt

2000-05-25T23:59:59.000Z

424

Differential expression of RANK on Langerhans cells and CD45RA and CD45RO/CLA on T cells in developing human skin after birth.  

E-Print Network [OSTI]

??Die Haut, die Schnittstelle zwischen dem Körper und der Umgebung, ist das größte Organ des Körpers und hat zahlreiche Funktionen. Eine davon ist, dass die… (more)

Akguen, Johnnie

2010-01-01T23:59:59.000Z

425

The Efficacy of a Broad-spectrum Sunscreen to Protect Engineered Human Skin from Tissue and DNA Damage Induced by Solar Ultraviolet Exposure  

Science Journals Connector (OSTI)

...Specifically, the capacity of sunscreens to prevent...and DNA damage after solar UV radiation. Engineered...DNA damage induced by solar ultraviolet exposure...Specifically, the capacity of sunscreens to prevent...and DNA damage after solar UV radiation. Engineered...

Vickram Bissonauth; Régen Drouin; David L. Mitchell; Marc Rhainds; Joël Claveau; and Mahmoud Rouabhia

2000-10-01T23:59:59.000Z

426

Action Spectra for Human Skin Cells: Estimates of the Relative Cytotoxicity of the Middle Ultraviolet, Near Ultraviolet, and Violet Regions of Sunlight on Epidermal Keratinocytes  

Science Journals Connector (OSTI)

...Spectroradiometric Measurements of Sunlight. The solar irradiance measurements were made...the epidermis, and the incident solar energy (under given conditions) at each...currently available for calculating solar irra diano: at given geographical...

Rex M. Tyrrell and Mireille Pidoux

1987-04-01T23:59:59.000Z

427

Enhancement of DNA repair in human skin cells by thymidine dinucleotides: Evidence for a p53-mediated mammalian SOS?response  

Science Journals Connector (OSTI)

...1562 , 7929831 . 24 Tishler R B Calderwood S K Coleman C N Price B D ( 1993 ) Cancer Res 53 : 2212 – 2216 , 8485705 . 25 Hupp T R Meek D W Midgley...35 Weeda G Van Ham R C A Masurel R Westerveld A Odijk H de Wit J Bootsma D van der Eb A J Hoeijmakers H J ( 1990 ) Mol Cell...

Mark S. Eller; Tomoko Maeda; Cristina Magnoni; Diana Atwal; Barbara A. Gilchrest

1997-01-01T23:59:59.000Z

428

Investigating impacts of natural and human-induced environmental changes on hydrological processes and flood hazards using a GIS-based hydrological/hydraulic model and remote sensing data  

E-Print Network [OSTI]

a GISbased hydrological and hydraulic modeling system, which incorporates state-of-the-art remote sensing data to simulate flood under various scenarios. The conceptual framework and technical issues of incorporating multi-scale remote sensing data...

Wang, Lei

2009-06-02T23:59:59.000Z

429

The Development of A Human Systems Simulation Laboratory: Strategic Direction  

SciTech Connect (OSTI)

The Human System Simulation Laboratory (HSSL) at the Idaho National Laboratory is one of few facilities of its kind that allows human factors researchers to evaluate various aspects of human performance and human system interaction for proposed reactor designs and upgrades. A basic system architecture, physical configuration and simulation capability were established to enable human factors researchers to support multiple, simultaneous simulations and also different power plant technologies. Although still evolving in terms of its technical and functional architecture, the HSSL is already proving its worth in supporting current and future nuclear industry needs for light water reactor sustainability and small modular reactors. The evolution of the HSSL is focused on continual physical and functional refinement to make it a fully equipped, reconfigurable facility where advanced research, testing and validation studies can be conducted on a wider range of reactor technologies. This requires the implementation of additional plant models to produce empirical research data on human performance with emerging human-system interaction technologies. Additional beneficiaries of this information include system designers and HRA practitioners. To ensure that results of control room crew studies will be generalizable to the existing and evolving fleet of US reactors, future expansion of the HSSL may also include other SMR plant models, plant-specific simulators and a generic plant model aligned to the current generation of pressurized water reactors (PWRs) and future advanced reactor designs. Collaboration with industry partners is also proving to be a vital component of the facility as this helps to establish a formal basis for current and future human performance experiments to support nuclear industry objectives. A long-range Program Plan has been developed for the HSSL to ensure that the facility will support not only the Department of Energy’s Light Water Reactor Sustainability Program, but also to provide human factors guidance for all future developments of the nuclear industry.

Jacques Hugo; Katya le Blanc; David Gertman

2012-07-01T23:59:59.000Z

430

Research Using Human Subjects/Materials  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Research Using Human SubjectsMaterials (taken in part from "Research on Human Specimens", National Institutes of Health) A 'human subject' is a living individual about whom an...

431

PIA - Human Resources Information System (HRIS) | Department...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

Information System (HRIS) PIA - Human Resources Information System (HRIS) PIA - Human Resources Information System (HRIS) PIA - Human Resources Information System (HRIS) More...

432

PIA - Human Resources Management Information System (HRMIS) ...  

Energy Savers [EERE]

Information System (HRMIS) PIA - Human Resources Management Information System (HRMIS) PIA - Human Resources Management Information System (HRMIS) PIA - Human Resources Management...

433

Human Genetics Portfolio Review Summary  

E-Print Network [OSTI]

the past 20 years, from our contribution to the Human Genome Project at the Sanger Institute to our role during this time. The drive to maximise the health benefits of human genome research remains a core to build research capacity and infrastructure to support human genetics and genomics · providing generous

Rambaut, Andrew

434

Human Capital Management Accountability Program  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

The Order establishes requirements, roles and responsibilities for the Human Capital Management Accountability Program (HCMAP) for human resources programs and personnel and ensures that human capital activities are regulatory and procedurally compliant with Federal statutes and Departmental policies. Does not cancel other directives.

2008-08-01T23:59:59.000Z

435

Eye Color in Humans  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Eye Color in Humans Eye Color in Humans Name: Kristi Location: N/A Country: N/A Date: N/A Question: The dominant characteristic is the one most likely to appear in the offspring. In human beings, brown is the dominant color for eyes. The children who inherit at least on dominant gene will have either brown, green, or hazel eyes. Only childten who inherit two recessive genes will have pure blue eyes. If there are eight children in the family, what color eyes will most of them have? Replies: http://www.newton.dep.anl.gov/archive.htm Search under eye color Steve Sample You answer is of course dependent on the genes of the parents. If both parents do not have the recessive gene, then no children will have light colored eyes. If one has a recessive gene and the other not, then still no children will have light color eyes and on the average 25% of the eight children could have the recessive gene. If both parents have the recessive gene, then 25% of the eight children could have light color eyes.

436

Dog vs. human language  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Dog vs. human language Dog vs. human language Name: Michelle Conte Location: N/A Country: N/A Date: N/A Question: Why can't dogs talk like humans? Replies: In very simple terms, they aren't made for it. In order to produce any kind of vocal sound, we not only need a set of vocal chords (or vibratory organs of some sort), we also need an air pipe and cranium shaped to deliver the vibrations in the right way -- you actually use your own head as a sort of sounding plate for several primary sounds (non-percussive) Dogs don't have the right shaped heads for the job, as well as the inability to vocalize many of the percussive sounds which make up a good percentage of our languages due to a differently shaped mouth. However, all things considered, we'd be ill-equipped to call meetings over long distances by simply howling, like dogs and their kin are wont to do in the wild.

437

Electromagnetic generator for harvesting energy from human motion  

Science Journals Connector (OSTI)

This paper presents an electromagnetic based generator which is suitable for supplying generating power from human body motion and has application in providing energy for body worn sensors or electronics devices. A prototype generator has been built and tested both by a shaker at resonance condition and also by human body motion during walking and slow running. The experimental results will show that the prototype could generate 300 ?W to 2.5 mW power from human body motion. The measured results are analyzed and compared with the theoretical model.

C.R. Saha; T. O’Donnell; N. Wang; P. McCloskey

2008-01-01T23:59:59.000Z

438

Dynamic Human Reliability Analysis: Benefits and Challenges of Simulating Human Performance  

SciTech Connect (OSTI)

To date, there has been considerable work on dynamic event trees and other areas related to dynamic probabilistic safety assessment (PSA). The counterpart to these efforts in human reliability analysis (HRA) has centered on the development of specific methods to account for the dynamic nature of human performance. In this paper, the author posits that the key to dynamic HRA is not in the development of specific methods but in the utilization of cognitive modeling and simulation to produce a framework of data that may be used in quantifying the likelihood of human error. This paper provides an overview of simulation approaches to HRA; reviews differences between first, second, and dynamic generation HRA; and outlines potential benefits and challenges of this approach.

R. L. Boring

2007-06-01T23:59:59.000Z

439

Factored Conditional Restricted Boltzmann Machines for Modeling Motion Style  

E-Print Network [OSTI]

). The result is an efficient, com- pact model whose effectiveness we demonstrate by modeling human motion. Like effective biases. The model would be much more powerful if the equilibrium sample at the higher level could

Roweis, Sam

440

E-Print Network 3.0 - autoimmune skin blistering Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

H II region, for which we have also constructed... as the blister model and the same ionizing star. We present and comment upon line intensity maps corresponding... when the...

Note: This page contains sample records for the topic "human skin model" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


441

A Gene Map of the Human Genome  

Science Journals Connector (OSTI)

...sanger.ac.uk/ Stanford Human Genome Center http://www-shgc.stanford.edu/ Wellcome Trust Centre for Human...sanger.ac.ukl Stanford Human Genome Center http://www-shgc.stanford.edu/ Wellcome Trust Centre for Human Genetics http...

G. D. Schuler; M. S. Boguski; E. A. Stewart; L. D. Stein; G. Gyapay; K. Rice; R. E. White; P. Rodriguez-Tomé; A. Aggarwal; E. Bajorek; S. Bentolila; B. B. Birren; A. Butler; A. B. Castle; N. Chiannilkulchai; A. Chu; C. Clee; S. Cowles; P. J. R. Day; T. Dibling; N. Drouot; I. Dunham; S. Duprat; C. East; C. Edwards; J.-B. Fan; N. Fang; C. Fizames; C. Garrett; L. Green; D. Hadley; M. Harris; P. Harrison; S. Brady; A. Hicks; E. Holloway; L. Hui; S. Hussain; C. Louis-Dit-Sully; J. Ma; A. MacGilvery; C. Mader; A. Maratukulam; T. C. Matise; K. B. McKusick; J. Morissette; A. Mungall; D. Muselet; H. C. Nusbaum; D. C. Page; A. Peck; S. Perkins; M. Piercy; F. Qin; J. Quackenbush; S. Ranby; T. Reif; S. Rozen; C. Sanders; X. She; J. Silva; D. K. Slonim; C. Soderlund; W.-L. Sun; P. Tabar; T. Thangarajah; N. Vega-Czarny; D. Vollrath; S. Voyticky; T. Wilmer; X. Wu; M. D. Adams; C. Auffray; N. A. R. Walter; R. Brandon; A. Dehejia; P. N. Goodfellow; R. Houlgatte; J. R. Hudson Jr.; S. E. Ide; K. R. Iorio; W. Y. Lee; N. Seki; T. Nagase; K. Ishikawa; N. Nomura; C. Phillips; M. H. Polymeropoulos; M. Sandusky; K. Schmitt; R. Berry; K. Swanson; R. Torres; J. C. Venter; J. M. Sikela; J. S. Beckmann; J. Weissenbach; R. M. Myers; D. R. Cox; M. R. James; D. Bentley; P. Deloukas; E. S. Lander; T. J. Hudson

1996-10-25T23:59:59.000Z

442

Mentoring Human Performance - 12480  

SciTech Connect (OSTI)

Although the positive effects of implementing a human performance approach to operations can be hard to quantify, many organizations and industry areas are finding tangible benefits to such a program. Recently, a unique mentoring program was established and implemented focusing on improving the performance of managers, supervisors, and work crews, using the principles of Human Performance Improvement (HPI). The goal of this mentoring was to affect behaviors and habits that reliably implement the principles of HPI to ensure continuous improvement in implementation of an Integrated Safety Management System (ISMS) within a Conduct of Operations framework. Mentors engaged with personnel in a one-on-one, or one-on-many dialogue, which focused on what behaviors were observed, what factors underlie the behaviors, and what changes in behavior could prevent errors or events, and improve performance. A senior management sponsor was essential to gain broad management support. A clear charter and management plan describing the goals, objectives, methodology, and expected outcomes was established. Mentors were carefully selected with senior management endorsement. Mentors were assigned to projects and work teams based on the following three criteria: 1) knowledge of the work scope; 2) experience in similar project areas; and 3) perceived level of trust they would have with project management, supervision, and work teams. This program was restructured significantly when the American Reinvestment and Recovery Act (ARRA) and the associated funding came to an end. The program was restructured based on an understanding of the observations, attributed successes and identified shortfalls, and the consolidation of those lessons. Mentoring the application of proven methods for improving human performance was shown effective at increasing success in day-to-day activities and increasing confidence and level of skill of supervisors. While mentoring program effectiveness is difficult to measure, and return on investment is difficult to quantify, especially in complex and large organizations where the ability to directly correlate causal factors can be challenging, the evidence presented by Sydney Dekker, James Reason, and others who study the field of human factors does assert managing and reducing error is possible. Employment of key behaviors-HPI techniques and skills-can be shown to have a significant impact on error rates. Our mentoring program demonstrated reduced error rates and corresponding improvements in safety and production. Improved behaviors are the result, of providing a culture with consistent, clear expectations from leadership, and processes and methods applied consistently to error prevention. Mentoring, as envisioned and executed in this program, was effective in helping shift organizational culture and effectively improving safety and production. (authors)

Geis, John A.; Haugen, Christian N. [CALIBRE Systems, Inc., Alexandria, Virginia (United States)

2012-07-01T23:59:59.000Z

443

Human Genome Program  

SciTech Connect (OSTI)

The DOE Human Genome program has grown tremendously, as shown by the marked increase in the number of genome-funded projects since the last workshop held in 1991. The abstracts in this book describe the genome research of DOE-funded grantees and contractors and invited guests, and all projects are represented at the workshop by posters. The 3-day meeting includes plenary sessions on ethical, legal, and social issues pertaining to the availability of genetic data; sequencing techniques, informatics support; and chromosome and cDNA mapping and sequencing.

Not Available

1993-01-01T23:59:59.000Z

444

Genetic Mapping of a Highly Variable Norovirus GII.4 Blockade Epitope: Potential Role in Escape from Human Herd Immunity  

Science Journals Connector (OSTI)

...polyclonal sera, 1988 outbreak human sera, and synthetic...polyclonal sera and 1988 outbreak human sera for the ability...therapeutics, and may help predict the emergence of future...economic costs of norovirus outbreaks are significant (23...culture or small-animal model for human NoVs, the...

Kari Debbink; Eric F. Donaldson; Lisa C. Lindesmith; Ralph S. Baric

2011-11-16T23:59:59.000Z

445

Caffeic Acid Directly Targets ERK1/2 to Attenuate Solar UV-Induced Skin Carcinogenesis  

Science Journals Connector (OSTI)

...Photon Source, an Office of Science User...Department of Energy Office of Science by the...caffeic acid. A, efficiency of ERK2 shRNA in...et alPHENIX: building new software for...Coot: model-building tools for molecular...

Ge Yang; Yang Fu; Margarita Malakhova; Igor Kurinov; Feng Zhu; Ke Yao; Haitao Li; Hanyong Chen; Wei Li; Do Young Lim; Yuqiao Sheng; Ann M. Bode; Ziming Dong; and Zigang Dong

2014-10-01T23:59:59.000Z

446

Tea Intake and Squamous Cell Carcinoma of the Skin: Influence of Type of Tea Beverages  

Science Journals Connector (OSTI)

...gender, with one control per household invited to participate using...including age, sex, and energy intake. Potential confounding...the final model. Age, sex, energy intake, inability to tan after...and diet in northern Kyushu, Japan. Jpn. J. Cancer Res...

Iman A. Hakim; Robin B. Harris; and Ute M. Weisgerber

2000-07-01T23:59:59.000Z

447

Report: EM Human Capital Initiatives  

Broader source: Energy.gov (indexed) [DOE]

HUMAN CAPITAL HUMAN CAPITAL September 25, 2008 Submitted by the EMAB Human Capital Subcommittee Background: The enhancement of the Office of Environmental Management's (EM) human capital has been a central tenet of the Assistant Secretary's tenure, reflecting the critical nature of this resource to the achievement of EM's mission. Beginning in Fiscal Year (FY) 2006, the Environmental Management Advisory Board (EMAB or Board) has reviewed the program's human capital issues and the plans EM has developed to address them. This review produced a number of recommendations that were presented in the Board's FY 2006 report to the Assistant Secretary and were later approved and implemented to varying degrees. * Recommendation 2006-01: Develop accountability for the Human Capital Plan

448

Human–robot interaction based on wearable IMU sensor and laser range finder  

Science Journals Connector (OSTI)

Abstract Service robots are not only expected to navigate within the environment, as they also will may with people. Human tracking by mobile robots is essential for service robots and human interaction applications. In this work, the goal is to add a more natural robot–human following in front based on the normal human gait model. This approach proposes implementing and evaluating a human–robot interaction strategy, using the integration of a LRF (Laser Range Finder) tracking of human legs with wearable IMU (Inertial Measurement Unit) sensors for capturing the human movement during the gait. The work was carried out in four stages: first, the definition of the model of human–robot interaction and the control proposal were developed. Second, the parameters based on the human gait were estimated. Third, the robot and sensor integration setup are also proposed. Finally, the description of the algorithm for parameters detection is presented. In the experimental study, despite of the continuous oscillation during the walking, the parameters estimation was precise and unbiased, showing also repeatability with human linear velocities changes. The controller was evaluated with an eight-shaped curve, showing the stability of the controller even with sharp changes in the human path during real experiments.

Carlos A. Cifuentes; Anselmo Frizera; Ricardo Carelli; Teodiano Bastos

2014-01-01T23:59:59.000Z

449

Modeling of Organizational Violence Violent Intent Modeling and Simulation (VIMS)  

E-Print Network [OSTI]

111 Modeling of Organizational Violence Violent Intent Modeling and Simulation (VIMS) Georgiy Bobashev, Burton Levine, Joe Eyerman, Michael Schwerin, and Richard Legault November 04, 2010 #12;2 VIMS Background #12;3 VIMS: Background · R&D sponsored by Human Factors Division at DHS S&T · Initial work

McShea, Daniel W.

450

Human Reliability Program Workshop  

SciTech Connect (OSTI)

A Human Reliability Program (HRP) is designed to protect national security as well as worker and public safety by continuously evaluating the reliability of those who have access to sensitive materials, facilities, and programs. Some elements of a site HRP include systematic (1) supervisory reviews, (2) medical and psychological assessments, (3) management evaluations, (4) personnel security reviews, and (4) training of HRP staff and critical positions. Over the years of implementing an HRP, the Department of Energy (DOE) has faced various challenges and overcome obstacles. During this 4-day activity, participants will examine programs that mitigate threats to nuclear security and the insider threat to include HRP, Nuclear Security Culture (NSC) Enhancement, and Employee Assistance Programs. The focus will be to develop an understanding of the need for a systematic HRP and to discuss challenges and best practices associated with mitigating the insider threat.

Landers, John; Rogers, Erin; Gerke, Gretchen

2014-05-18T23:59:59.000Z

451

Annotating individual human genomes  

Science Journals Connector (OSTI)

Advances in DNA sequencing technologies have made it possible to rapidly, accurately and affordably sequence entire individual human genomes. As impressive as this ability seems, however, it will not likely amount to much if one cannot extract meaningful information from individual sequence data. Annotating variations within individual genomes and providing information about their biological or phenotypic impact will thus be crucially important in moving individual sequencing projects forward, especially in the context of the clinical use of sequence information. In this paper we consider the various ways in which one might annotate individual sequence variations and point out limitations in the available methods for doing so. It is arguable that, in the foreseeable future, DNA sequencing of individual genomes will become routine for clinical, research, forensic, and personal purposes. We therefore also consider directions and areas for further research in annotating genomic variants.

Ali Torkamani; Ashley A. Scott-Van Zeeland; Eric J. Topol; Nicholas J. Schork

2011-01-01T23:59:59.000Z

452

Electric dipole response of 208Pb from proton inelastic scattering: constraints on neutron skin thickness and symmetry energy  

E-Print Network [OSTI]

The electric dipole (E1) response of 208Pb has been precisely determined by measuring Coulomb excitation induced by proton scattering at very forward angles. The electric dipole polarizability, defined as inverse energy-weighted sum rule of the E1 strength, has been extracted as 20.1+-0.6 fm^3. The data can be used to constrain the neutron skin thickness of 208Pb to 0.168(+-0.009)_expt(+-0.013)_theo(+-0.021)_est fm, where the subscript "expt" refers to the experimental uncertainty, "theor" to the theoretical confidence band and "est" to the uncertainty associated with the estimation of the symmetry energy at the saturation density. In addition, a constraint band has been extracted in the plane of the symmetry energy (J) and its slope parameter (L) at the saturation density.

A. Tamii; P. von Neumann-Cosel; I. Poltoratska

2013-07-10T23:59:59.000Z

453

Constraints on the symmetry energy and neutron skins from experiments and theory  

E-Print Network [OSTI]

The symmetry energy contribution to the nuclear Equation of State (EoS) impacts various phenomena in nuclear astrophysics, nuclear structure, and nuclear reactions. Its determination is a key objective of contemporary nuclear physics with consequences for the understanding of dense matter within neutron stars. We examine the results of laboratory experiments that have provided initial constraints on the nuclear symmetry energy and its density dependence at and somewhat below normal nuclear matter density. Some of these constraints have been derived from properties of nuclei. Others have been derived from the nuclear response to electroweak and hadronic probes. We also examine the most frequently used theoretical models that predict the symmetry energy and its slope. By comparing existing constraints on the symmetry pressure to theories, we demonstrate how the contribution of the three-body force, an essential ingredient in neutron matter models, can be determined.

Tsang, M B; Camera, F; Danielewicz, P; Gandolfi, S; Hebeler, K; Horowitz, C J; Lee, Jenny; Lynch, W G; Kohley, Z; Lemmon, R; Moller, P; Murakami, T; Riordan, S; Roca-Maza, X; Sammarruca, F; Steiner, A W; Vidaña, I; Yennello, S J

2012-01-01T23:59:59.000Z

454

Constraints on the symmetry energy and neutron skins from experiments and theory  

E-Print Network [OSTI]

The symmetry energy contribution to the nuclear Equation of State (EoS) impacts various phenomena in nuclear astrophysics, nuclear structure, and nuclear reactions. Its determination is a key objective of contemporary nuclear physics with consequences for the understanding of dense matter within neutron stars. We examine the results of laboratory experiments that have provided initial constraints on the nuclear symmetry energy and its density dependence at and somewhat below normal nuclear matter density. Some of these constraints have been derived from properties of nuclei. Others have been derived from the nuclear response to electroweak and hadronic probes. We also examine the most frequently used theoretical models that predict the symmetry energy and its slope. By comparing existing constraints on the symmetry pressure to theories, we demonstrate how the contribution of the three-body force, an essential ingredient in neutron matter models, can be determined.

M. B. Tsang; J. R. Stone; F. Camera; P. Danielewicz; S. Gandolfi; K. Hebeler; C. J. Horowitz; Jenny Lee; W. G. Lynch; Z. Kohley; R. Lemmon; P. Moller; T. Murakami; S. Riordan; X. Roca-Maza; F. Sammarruca; A. W. Steiner; I. Vidaña; S. J. Yennello

2012-04-02T23:59:59.000Z

455

A human reliability analysis of a nuclear explosives dismantlement  

SciTech Connect (OSTI)

This paper describes the methodology used in a human reliability analysis (HRA) conducted during a quantitative hazard assessment of a nuclear weapon disassembly process performed at the Pantex plant. The probability of human errors during the disassembly process is an extremely important aspect of estimating accident-sequence frequency for nuclear weapons processing. The methods include the systematic identification of potential human-initiated or enabled accident sequences using an accident-sequence fault tree, the extensive use of walkthroughs and videotaping of the disassembly process, and hands-on testing of postulated human errors. THERP modeling of rule-based behavior and operational data analysis of errors in skill-based behavior are described. A simple method for evaluating the approximate likelihood of nonmalevolent violations of procedures was developed and used to examine the process. The HRA occurred concurrently with process design, so considerable interaction between the analysts and designers occurred and resulted in design changes that are discussed in the paper.

Bott, T.F.

1995-07-01T23:59:59.000Z

456

Directed Differentiation and Functional Maturation of Cortical Interneurons from Human Embryonic Stem Cells  

Science Journals Connector (OSTI)

Summary Human pluripotent stem cells are a powerful tool for modeling brain development and disease. The human cortex is composed of two major neuronal populations: projection neurons and local interneurons. Cortical interneurons comprise a diverse class of cell types expressing the neurotransmitter GABA. Dysfunction of cortical interneurons has been implicated in neuropsychiatric diseases, including schizophrenia, autism, and epilepsy. Here, we demonstrate the highly efficient derivation of human cortical interneurons in an NKX2.1::GFP human embryonic stem cell reporter line. Manipulating the timing of SHH activation yields three distinct GFP+ populations with specific transcriptional profiles, neurotransmitter phenotypes, and migratory behaviors. Further differentiation in a murine cortical environment yields parvalbumin- and somatostatin-expressing neurons that exhibit synaptic inputs and electrophysiological properties of cortical interneurons. Our study defines the signals sufficient for modeling human ventral forebrain development in vitro and lays the foundation for studying cortical interneuron involvement in human disease pathology.

Asif M. Maroof; Sotirios Keros; Jennifer A. Tyson; Shui-Wang Ying; Yosif M. Ganat; Florian T. Merkle; Becky Liu; Adam Goulburn; Edouard G. Stanley; Andrew G. Elefanty; Hans Ruedi Widmer; Kevin Eggan; Peter A. Goldstein; Stewart A. Anderson; Lorenz Studer

2013-01-01T23:59:59.000Z

457

Sensory impact of skin contact on white wines characterized by descriptive analysis, time–intensity analysis and temporal dominance of sensations analysis  

Science Journals Connector (OSTI)

Abstract In white wine fermentation, extended skin contact of crushed grapes is frequently used to increase the varietal aromas of white Riesling and Gewürztraminer wines. At the same time, phenolic compounds are extracted which can yield significant increases in bitterness and/or astringency. Descriptive analysis (DA), time–intensity analysis (TI) and temporal dominance of sensation (TDS) analysis were used to evaluate the changes in flavor of Riesling and Gewürztraminer wines made with varying skin contact times. DA showed that Riesling wines differed only in bitterness and color. In contrast, Gewürztraminer wines varied significantly in bitterness, sweetness, sourness, and astringency as well as for several aroma notes and color. 2009 and 2010 Gewürztraminer wines increased in intensity of honey/caramel, floral, and lemon aromas as well as yellow color, whereas peach/apricot was only significant in 2009 and apple and green grass/green banana only in 2010. Regarding the temporal properties of orally perceived modalities, bitterness TI curves recorded from Gewürztraminer differed significantly in maximum intensity and area under the curve, while Riesling showed no significant differences in any TI parameter. Increasing skin contact altered the dominance of orally perceived attributes. Fermenting the grapes completely on their skins produced a wine, which was significantly more bitter than all other wines according to TI and DA. However TDS analysis showed that the dominating sensation in this wine was not the bitter taste but the astringent mouth feel. TDS revealed further subtle differences caused by botrytized grape material, altering sourness and astringent perception.

Martina Sokolowsky; Annett Rosenberger; Ulrich Fischer

2015-01-01T23:59:59.000Z

458

Individual Differences in Human Reliability Analysis  

SciTech Connect (OSTI)

While human reliability analysis (HRA) methods include uncertainty in quantification, the nominal model of human error in HRA typically assumes that operator performance does not vary significantly when they are given the same initiating event, indicators, procedures, and training, and that any differences in operator performance are simply aleatory (i.e., random). While this assumption generally holds true when performing routine actions, variability in operator response has been observed in multiple studies, especially in complex situations that go beyond training and procedures. As such, complexity can lead to differences in operator performance (e.g., operator understanding and decision-making). Furthermore, psychological research has shown that there are a number of known antecedents (i.e., attributable causes) that consistently contribute to observable and systematically measurable (i.e., not random) differences in behavior. This paper reviews examples of individual differences taken from operational experience and the psychological literature. The impact of these differences in human behavior and their implications for HRA are then discussed. We propose that individual differences should not be treated as aleatory, but rather as epistemic. Ultimately, by understanding the sources of individual differences, it is possible to remove some epistemic uncertainty from analyses.

Jeffrey C. Joe; Ronald L. Boring

2014-06-01T23:59:59.000Z

459

RECRUITMENT SEARCH FIRMS HUMAN RESOURCES  

E-Print Network [OSTI]

RECRUITMENT SEARCH FIRMS HUMAN RESOURCES GUIDELINES Workforce Planning | Washington Square, San by the Workforce Planning Unit in Human Resources at SJSU. Process Consistent, defensible processes for evaluating of the recruitment. - At this meeting, the Workforce Planning analyst can provide contact information for search

Su, Xiao

460

Human viruses: discovery and emergence  

Science Journals Connector (OSTI)

...whether or not it poses a risk to humans, would be...will pose a serious risk to public health but...situation will require both political will and considerable investment in infrastructure...Woolhouse, M. E. J. 2001 Risk factors for human disease...

2012-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "human skin model" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


461

The human activity of visualization  

E-Print Network [OSTI]

Griffin et al 2006 #12;Human-Computer Interaction: Software of the Mind each user has a setThe human activity of visualization cultural and psychological factors in representation; Gibbon 1998; Marcus 2000) conventions and metaphors of Westerners may not hold worldwide colors

Wright, Dawn Jeannine

462

Macroscopically frustrated Ising model  

Science Journals Connector (OSTI)

A disordered spin-glass model in which both static and dynamical properties depend on macroscopic magnetizations is presented. These magnetizations interact via random couplings and, therefore, the typical quenched realization of the system exhibits a macroscopic frustration. The model is solved by using a revisited replica approach, and the broken symmetry solution turns out to coincide with the symmetric solution. Some dynamical aspects of the model are also discussed, showing how it could be a useful tool for describing some properties of real systems such as, for example, natural ecosystems or human social systems.

M. Pasquini and M. Serva

2001-04-16T23:59:59.000Z

463

Reversibility of Pt-Skin and Pt-Skeleton Nanostructures in Acidic Media  

Science Journals Connector (OSTI)

In acidic and oxidizing conditions, Pt is the only metal that can efficiently catalyze the oxygen reduction reaction (ORR), the reaction that limits the PEMFC performance. ... In this paper, atomically resolved pictures of the different nanostructures that can be derived from a benchmark Pt3Co/C catalyst in a model PEMFC environment were obtained. ... The electrocatalytic trends established for extended surfaces are used to explain the activity pattern of Pt3M nanocatalysts as well as to provide a fundamental basis for the catalytic enhancement of cathode catalysts. ...

Julien Durst; Miguel Lopez-Haro; Laetitia Dubau; Marian Chatenet; Yvonne Soldo-Olivier; Laure Guétaz; Pascale Bayle-Guillemaud; Frédéric Maillard

2014-01-14T23:59:59.000Z

464

Human Genome Research: Decoding DNA  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Human Genome Research: Decoding DNA Human Genome Research: Decoding DNA Resources with Additional Information Charles DeLisi As head of DOE's Office of Health and Environmental Research, Charles DeLisi played a pivotal role in proposing and initiating the Human Genome Program in 1986. The U.S. Department of Energy (DOE) has historically been active in supporting human genome research. On September 10, 2003, Secretary of Energy Spencer Abraham presented the Secretary's Gold Award to Aristides Patrinos and Francis Collins for their leadership of the government's Human Genome Project. At DOE's Office of Science, Dr. Patrinos is the Associate Director for Biological and Environmental Research. He has been a researcher at the department's Oak Ridge National Laboratory and Brookhaven National Laboratory.

465

A Paired, Double-Blind, Randomized Comparison of a Moisturizing Durable Barrier Cream to 10% Glycerine Cream in the Prophylactic Management of Postmastectomy Irradiation Skin Care: Trans Tasman Radiation Oncology Group (TROG) 04.01  

SciTech Connect (OSTI)

Purpose: A previous, unblinded study demonstrated that an alcohol-free barrier film containing an acrylate terpolymer (ATP) was effective in reducing skin reactions compared with a 10% glycerine cream (sorbolene). The different appearances of these products precluded a blinded comparison. To test the acrylate terpolymer principle in a double-blinded manner required the use of an alternative cream formulation, a moisturizing durable barrier cream (MDBC); the study was conducted by the Trans Tasman Radiation Oncology Group (TROG) as protocol 04.01. Methods and Materials: A total of 333 patients were randomized; 1 patient was ineligible and 14 patients withdrew or had less than 7 weeks' observations, leaving 318 for analysis. The chest wall was divided into medial and lateral compartments, and patients were randomized to have MDBC applied daily to the medial or lateral compartment and sorbolene to the other compartment. Weekly observations, photographs, and symptom scores (pain and pruritus) were collected to week 12 or resolution of skin reactions if earlier. Skin dose was confirmed by centrally calibrated thermoluminescent dosimeters. Results: Rates of medial and lateral compartment Common Toxicity Criteria (CTC), version 3, greater than or equal to grade 3 skin reactions were 23% and 41%, but rates by skin care product were identical at 32%. There was no significant difference between MDBC and sorbolene in the primary endpoint of peak skin reactions or secondary endpoints of area-under-the-curve skin reaction scores. Conclusions: The MDBC did not reduce the peak skin reaction compared to sorbolene. It is possible that this is related to the difference in the formulation of the cream compared with the film formulation. Skin dosimetry verification and double blinding are essential for radiation skin care comparative studies.

Graham, Peter H., E-mail: peter.graham@sesiahs.health.nsw.gov.au [Cancer Care Centre, St. George Hospital, Kogarah, New South Wales (Australia); Plant, Natalie; Graham, Jennifer L.; Browne, Lois [Cancer Care Centre, St. George Hospital, Kogarah, New South Wales (Australia)] [Cancer Care Centre, St. George Hospital, Kogarah, New South Wales (Australia); Borg, Martin [Department of Radiation Oncology, Royal Adelaide Hospital (Australia)] [Department of Radiation Oncology, Royal Adelaide Hospital (Australia); Capp, Anne [Department of Radiation Oncology, Mater Hospital, Newcastle, New South Wales (Australia)] [Department of Radiation Oncology, Mater Hospital, Newcastle, New South Wales (Australia); Delaney, Geoff P. [Cancer Care Centre, Liverpool Hospital, Liverpool, New South Wales (Australia)] [Cancer Care Centre, Liverpool Hospital, Liverpool, New South Wales (Australia); Harvey, Jennifer [Mater Hospital, South Brisbane, Queensland (Australia)] [Mater Hospital, South Brisbane, Queensland (Australia); Kenny, Lisbeth [Royal Brisbane Hospital, Herston, Queensland (Australia)] [Royal Brisbane Hospital, Herston, Queensland (Australia); Francis, Michael [Andrew Love Cancer Centre, Geelong (Australia)] [Andrew Love Cancer Centre, Geelong (Australia); Zissiadis, Yvonne [Department of Radiation Oncology, Royal Perth Hospital, Perth (Australia)] [Department of Radiation Oncology, Royal Perth Hospital, Perth (Australia)

2013-05-01T23:59:59.000Z

466

Inferring human mobility patterns from taxicab location traces  

Science Journals Connector (OSTI)

Taxicabs equipped with real-time location sensing devices are increasingly becoming popular. Such location traces are a rich source of information and can be used for congestion pricing, taxicab placement, and improved city planning. An important problem ... Keywords: hidden markov models, human mobility patterns, taxi cab occupancy, trajectory analysis

Raghu Ganti; Mudhakar Srivatsa; Anand Ranganathan; Jiawei Han

2013-09-01T23:59:59.000Z

467

Population stability, cooperation, and the invasibility of the human species  

E-Print Network [OSTI]

a mechanism for these outcomes by modifying a simple density-dependent population model to allow varying populations expanded out of Africa and spread rapidly across the majority of the earth's land surfacePopulation stability, cooperation, and the invasibility of the human species Marcus J. Hamiltona

Brown, James H.

468

Human Reliability Analysis for Digital Human-Machine Interfaces  

SciTech Connect (OSTI)

This paper addresses the fact that existing human reliability analysis (HRA) methods do not provide guidance on digital human-machine interfaces (HMIs). Digital HMIs are becoming ubiquitous in nuclear power operations, whether through control room modernization or new-build control rooms. Legacy analog technologies like instrumentation and control (I&C) systems are costly to support, and vendors no longer develop or support analog technology, which is considered technologically obsolete. Yet, despite the inevitability of digital HMI, no current HRA method provides guidance on how to treat human reliability considerations for digital technologies.

Ronald L. Boring

2014-06-01T23:59:59.000Z

469

On the detection of low-resolution skin regions in surveillance images Nils Janssen and Neil Robertson  

E-Print Network [OSTI]

human motion. Multi-dimensional histograms are an intuitive way to represent colour distributions in computer vision applications (e.g. lighting changes, camera gain etc.) it re- mains a powerful descriptor

Paris-Sud XI, Université de

470

Towards Human Motion Capturing using Gyroscopeless Orientation Estimation Computer Science, TU Darmstadt  

E-Print Network [OSTI]

Towards Human Motion Capturing using Gyroscopeless Orientation Estimation Ulf Blanke Computer using body model-based action-primitives [1, 8]. Different techniques can capture human motion. Tracker to be powerful for various areas, such as for the entertainment industry or re- cently for healthcare

471

"Studying human behavior using tools from engineering in order to make robots move in  

E-Print Network [OSTI]

Classification and Segmentation Extracting features of interest from human motion data (i.e., from mocap systems in order to recreate the original human motion and measure of our notion of quality. Stylistic Movement with the Hybrid and Networked Systems (HyNeSs) Lab at Boston University we extend the power of this model

Acton, Scott

472

Experimental comparison of torque control methods on an ankle exoskeleton during human walking  

E-Print Network [OSTI]

Experimental comparison of torque control methods on an ankle exoskeleton during human walking, a neuromuscular model, or electromyography. Controllers were implemented on a tethered ankle exoskeleton--Rehabilitation Robotics, Ankle Exoskeleton, Torque Control, Human-Robot Interaction I. INTRODUCTION Exoskeletons have been

Collins, Steven H.

473

MORPHOLOGY ANALYSIS OF HUMAN KNEE USING MR IMAGERY D. Chetverikov1,2, G. Renner1  

E-Print Network [OSTI]

MORPHOLOGY ANALYSIS OF HUMAN KNEE USING MR IMAGERY D. Chetverikov1,2, G. Renner1 1 Computer a novel system for building a 3D model of human knee based on a sequence MR images. The system applies tools can be applied to the analysis of the kinematic behaviour of the knee. In the medical practice, MR

Chetverikov, Dmitry

474

Eunice Kennedy Shriver National Institute of Child Health and Human Development  

E-Print Network [OSTI]

, and Dose Response · Building in vitro Models for Environmental Research · Early Life Determinants the life course and beyond, to future generations. Advancing our understanding of the environmental impacts of Air Pollution on Human Health · Water Pollution and Human Health · Multiple Exposures, Mixtures

Rau, Don C.

475

Tracking of Multiple Faces for Human-Computer Interfaces and Virtual Environments  

E-Print Network [OSTI]

Tracking of Multiple Faces for Human-Computer Interfaces and Virtual Environments Fu Jie Huang present a tracking software library based on this algorithm. This library can be applied to human-computer based on statistical color modeling and the deformable template. We then expand the algorithm to track

Beimel, Amos

476

Depleted uranium human health risk assessment, Jefferson Proving Ground, Indiana  

SciTech Connect (OSTI)

The risk to human health from fragments of depleted uranium (DU) at Jefferson Proving Ground (JPG) was estimated using two types of ecosystem pathway models. A steady-state, model of the JPG area was developed to examine the effects of DU in soils, water, and vegetation on deer that were hunted and consumed by humans. The RESRAD code was also used to estimate the effects of farming the impact area and consuming the products derived from the farm. The steady-state model showed that minimal doses to humans are expected from consumption of deer that inhabit the impact area. Median values for doses to humans range from about 1 mrem ({plus_minus}2.4) to 0.04 mrem ({plus_minus}0.13) and translate to less than 1 {times} 10{sup {minus}6} detriments (excess cancers) in the population. Monte Carlo simulation of the steady-state model was used to derive the probability distributions from which the median values were drawn. Sensitivity analyses of the steady-state model showed that the amount of DU in airborne dust and, therefore, the amount of DU on the vegetation surface, controlled the amount of DU ingested by deer and by humans. Human doses from the RESRAD estimates ranged from less than 1 mrem/y to about 6.5 mrem/y in a hunting scenario and subsistence fanning scenario, respectively. The human doses exceeded the 100 mrem/y dose limit when drinking water for the farming scenario was obtained from the on-site aquifer that was presumably contaminated with DU. The two farming scenarios were unrealistic land uses because the additional risk to humans due to unexploded ordnance in the impact area was not figured into the risk estimate. The doses estimated with RESRAD translated to less than 1 {times} 10{sup {minus}6} detriments to about 1 {times} 10{sup {minus}3} detriments. The higher risks were associated only with the farming scenario in which drinking water was obtained on-site.

Ebinger, M.H.; Hansen, W.R.

1994-04-29T23:59:59.000Z

477

A framework for human microbiome research  

E-Print Network [OSTI]

A variety of microbial communities and their genes (the microbiome) exist throughout the human body, with fundamental roles in human health and disease. The National Institutes of Health (NIH)-funded Human Microbiome Project ...

Friedman, Jonathan

478

Human genome. 1993 Program report  

SciTech Connect (OSTI)

The purpose of this report is to update the Human Genome 1991-92 Program Report and provide new information on the DOE genome program to researchers, program managers, other government agencies, and the interested public. This FY 1993 supplement includes abstracts of 60 new or renewed projects and listings of 112 continuing and 28 completed projects. These two reports, taken together, present the most complete published view of the DOE Human Genome Program through FY 1993. Research is progressing rapidly toward 15-year goals of mapping and sequencing the DNA of each of the 24 different human chromosomes.

Not Available

1994-03-01T23:59:59.000Z

479

Basic model Basic model  

E-Print Network [OSTI]

Early days Basic model Literature Classical literature Bayes pre-MCMC Bayes post-MCMC Basic model systems via latent factors Hedibert Freitas Lopes Booth School of Business University of Chicago Col / 66 #12;Early days Basic model Literature Classical literature Bayes pre-MCMC Bayes post-MCMC Basic

Liu, I-Shih

480

The HuMAnS toolbox, a homogenous framework for motion capture, analysis and simulation  

E-Print Network [OSTI]

measures given by multiple sensors. They allow as well simulating precisely human motion, with a muscle environment. These models can be interconnected and processed then with the help of Scilab's powerful

Paris-Sud XI, Université de

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481

Professional Human Capital Flows: Temporal Structure of Loss, Replacement and Contingent Bundling Effects on Firm Performance  

E-Print Network [OSTI]

diversification, but the opposite is true of prior performance and the manager-subordinate ratio. Implications for RBT, the attraction-selection-attrition (ASA) model, and strategic human capital theory are discussed....

Brymer, Rhett

2012-10-19T23:59:59.000Z

482

Corporate Human Resources Information Services (CHIRS) PIA, Office...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

Corporate Human Resources Information Services (CHIRS) PIA, Office of Human Capitol Management Corporate Human Resources Information Services (CHIRS) PIA, Office of Human Capitol...

483

Accident Sequence Evaluation Program: Human reliability analysis procedure  

SciTech Connect (OSTI)

This document presents a shortened version of the procedure, models, and data for human reliability analysis (HRA) which are presented in the Handbook of Human Reliability Analysis With emphasis on Nuclear Power Plant Applications (NUREG/CR-1278, August 1983). This shortened version was prepared and tried out as part of the Accident Sequence Evaluation Program (ASEP) funded by the US Nuclear Regulatory Commission and managed by Sandia National Laboratories. The intent of this new HRA procedure, called the ''ASEP HRA Procedure,'' is to enable systems analysts, with minimal support from experts in human reliability analysis, to make estimates of human error probabilities and other human performance characteristics which are sufficiently accurate for many probabilistic risk assessments. The ASEP HRA Procedure consists of a Pre-Accident Screening HRA, a Pre-Accident Nominal HRA, a Post-Accident Screening HRA, and a Post-Accident Nominal HRA. The procedure in this document includes changes made after tryout and evaluation of the procedure in four nuclear power plants by four different systems analysts and related personnel, including human reliability specialists. The changes consist of some additional explanatory material (including examples), and more detailed definitions of some of the terms. 42 refs.

Swain, A.D.

1987-02-01T23:59:59.000Z

484

Scientists Help Define the Healthy Human Microbiome  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Scientists Help Define the Healthy Human Microbiome Scientists Help Define the Healthy Human Microbiome Computing, bioinformatics, and microbial ecology resources play key role in...

485

Error Modeling in the ACT-R Production System Christian Lebire  

E-Print Network [OSTI]

Error Modeling in the ACT-R Production System Christian Lebière Department of Psychology Carnegie to extend the ACT-R production system to model human errors in the performance of a high-level cognitive be successfully duplicated in production system models. Introduction ACT-R (Anderson, 1993) is a model of human

Reder, Lynne

486

Sequence of the most informative joints (SMIJ): A new representation for human skeletal action recognition  

Science Journals Connector (OSTI)

Much of the existing work on action recognition combines simple features with complex classifiers or models to represent an action. Parameters of such models usually do not have any physical meaning nor do they provide any qualitative insight relating ... Keywords: Bag-of-words, Berkeley MHAD, Cross-database generalization, HDM05, Human action recognition, Human action representation, Informative joints, Linear dynamical systems, MSR Action3D, Normalized edit distance

Ferda Ofli; Rizwan Chaudhry; Gregorij Kurillo; René Vidal; Ruzena Bajcsy

2014-01-01T23:59:59.000Z

487

Perception for Human Motion Understanding  

Science Journals Connector (OSTI)

The fact that people are embodied places powerful constraints on their motion. By leveraging these constraints, we can build systems to perceive human motion that are fast and robust. More importantly, by unde...

Christopher R. Wren

2005-01-01T23:59:59.000Z

488

The water footprint of humanity  

Science Journals Connector (OSTI)

...America (the United States, Canada, Brazil, and Argentina...Ehrlich PR ( 1996 ) Human appropriation of renewable fresh water . Science 271 : 785 – 788 . 6...domestic water supply sector. Water use in energy production is included in the figures...

Arjen Y. Hoekstra; Mesfin M. Mekonnen

2012-01-01T23:59:59.000Z

489

Director Human Resources Assoc Director  

E-Print Network [OSTI]

Director ­ Human Resources Assoc Director Workforce Planning & Organisational Change Director) - Organisational change - Workforce planning - Grievance & performance mgt support - Performance management line and not a formal Branch ** Includes Classifications ANU Search Workforce Planning* Remunerations

Botea, Adi

490

Unravelling daily human mobility motifs  

E-Print Network [OSTI]

Human mobility is differentiated by time scales. While the mechanism for long time scales has been studied, the underlying mechanism on the daily scale is still unrevealed. Here, we uncover the mechanism responsible for ...

Schneider, Christian M.

491

Molecular evolution of human paramyxoviruses  

Science Journals Connector (OSTI)

The nucleotide sequences of the NP and M genes of human parainfluenza type 1 virus (HPIV-1) were determined. The NP gene was 1677 nucleotides long excluding polyadenylic acid. The NP gene contained a single la...

K. Miyahara; S. Kitada; M. Yoshimoto; H. Matsumura; M. Kawano…

1992-01-01T23:59:59.000Z

492

HUMAN RESOURCES SIMON FRASER UNIVERSITY  

E-Print Network [OSTI]

. The position is responsible for developing test scenarios, responding to system problems by investigating regarding the design of testing scenarios and scripts and how to evaluate outcomes. Makes decisions1 HUMAN RESOURCES SIMON FRASER UNIVERSITY TEMPORARY ADMINISTRATIVE & PROFESSIONAL STAFF POSITION

493

Posthumanity, Transhumanism and Human Nature  

Science Journals Connector (OSTI)

...“Posthumanity” has established itself as a label for a form of human existence radically transformed by the most advanced medical techniques and by the use of neuro, bio and nano and other technologies for hum...

Dieter Birnbacher

2009-01-01T23:59:59.000Z

494

Technological Transformation of Human Experience  

Science Journals Connector (OSTI)

This article was inspired by Don Ihde's work on the experience of technology in human-machine relations. (See Don Ihde. "The Experience of Technology," Cultural Hermeneutics, Vol. 2, 1974, pp. 267-279.)

Arun Kumar Tripathi

2008-07-01T23:59:59.000Z

495

The water footprint of humanity  

Science Journals Connector (OSTI)

...the United Arab Emirates (571), Egypt (527...Ehrlich PR ( 1996 ) Human appropriation of renewable fresh water . Science 271 : 785 – 788 . 6...domestic water supply sector. Water use in energy production is included in the figures...

Arjen Y. Hoekstra; Mesfin M. Mekonnen

2012-01-01T23:59:59.000Z

496

Coördinating human-robot communication  

E-Print Network [OSTI]

As robots begin to emerge from the cloisters of industrial and military applications and enter the realms of coöperative partners for people, one of the most important facets of human-robot interaction (HRI) will be ...

Brööks, Andrëw G. (Brööks Zoz)

2007-01-01T23:59:59.000Z

497

The water footprint of humanity  

Science Journals Connector (OSTI)

...the United Arab Emirates (571), Egypt (527...world ( UNESCO , London ). 5 Postel SL Daily GC Ehrlich PR ( 1996 ) Human appropriation of...2008 ) The global component of freshwater demand and supply: An assessment of virtual water...

Arjen Y. Hoekstra; Mesfin M. Mekonnen

2012-01-01T23:59:59.000Z

498

Robot Manipulation in Human Environments  

E-Print Network [OSTI]

Human environments present special challenges for robot manipulation. They are often dynamic, difficult to predict, and beyond the control of a robot engineer. Fortunately, many characteristics of these settings can be ...

Edsinger, Aaron

2007-01-16T23:59:59.000Z

499

Robot manipulation in human environments  

E-Print Network [OSTI]

Human environments present special challenges for robot manipulation. They are often dynamic, difficult to predict, and beyond the control of a robot engineer. Fortunately, many characteristics of these settings can be ...

Edsinger, Aaron Ladd, 1972-

2007-01-01T23:59:59.000Z

500

Contractor Human Resource Management Programs  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

The purpose of this directive is to establish Department of Energy (DOE) responsibilities and requirements for the management and oversight of contractor Human Resource Management (HR) programs. Chg 1, 5-8-98; Chg 2, 11-22-09

1996-09-30T23:59:59.000Z