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Note: This page contains sample records for the topic "human radiation experiments" from the National Library of EnergyBeta (NLEBeta).
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1

Human Radiation Experiments: What's New  

NLE Websites -- All DOE Office Websites (Extended Search)

of Defense Report Finding Aids Department of Defense Report on Search for Human Radiation Experiments Records 1944-1994 Exit Human Radiation Experiments Site This...

2

Disposition Schedule: Human Radiation Experiments | Department...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Schedule: Human Radiation Experiments Disposition Schedule: Human Radiation Experiments This database contains information on records collections related to human radiation...

3

Human Radiation Experiments: Multimedia  

NLE Websites -- All DOE Office Websites (Extended Search)

the oral histories of researchers and others possessing firsthand knowledge of human radiation experimentation during World War II and the Cold War. Film Clips: Document...

4

Human Radiation Experiments: Related Sites  

NLE Websites -- All DOE Office Websites (Extended Search)

Experiment Experiment Related Sites Related Links Home Roadmap What's New Search HREX Multimedia Related Sites Federal DOE DOE Sites & National Laboratories Federal Other The following are organizations which provide related information and links to databases, electronic documents, and servers. FEDERAL - DOE U.S. Department of Energy (DOE) homepage (http://www.doe.gov/)contains information on DOE's Departmental Resources, Programs, Offices, National Labs and other DOE related topics. DOE's Environment, Safety and Health (ES&H) Technical Information Services (TIS) homepage (http://nattie.eh.doe.gov/) is a collection of information services designed to provide safety and health professionals with reliable, accurate and current information to assist them in performing their jobs.

5

DOE Openess: Human Radiation Experiments - Roadmap to the Project  

NLE Websites -- All DOE Office Websites (Extended Search)

Radiation Experiments: Roadmap to the Project DOE Shield DOE Openness: Human Radiation Experiment Roadmap to the Project Roadmap to the Project Home Roadmap What's New Search HREX...

6

Interim report of the Advisory Committee on human radiation experiments  

SciTech Connect

The Advisory Committee on Human Radiation Experiments was created by President Clinton to advise the Human Radiation Interagency Working Group on the ethical and scientific criteria applicable to human radiation experiments carried out or sponsored by the U.S. Government. The Committee seeks to answer several fundamental question: What ethics criteria should be used to evaluate human radiation experiments? What was the Federal Government`s role in human radiation experiments? What are the criteria for determining appropriate Federal responses where wrongs or harms have occurred? What lessons learned from studying past and present research standards and practices should be applied to the future? The Committee has been gathering vast amounts of information and working to render it orderly and accessible. In the next six months, the Committee will continue with the tasks of data gathering and organizing. The focus of the work, however, will be developing criteria for judging historical and contemporary experiments, policies, and procedures, as well as criteria for remedies that may be appropriate where harms or wrongs have ocurred. Based on findings, the Committee will make specific recommendations regarding policies for the future.

Not Available

1994-10-21T23:59:59.000Z

7

Human Radiation Experiments: Roadmap to the Project: ACHRE Report  

NLE Websites -- All DOE Office Websites (Extended Search)

Advisory Committee on Human Radiation Experiments - Executive Summary Advisory Committee on Human Radiation Experiments - Executive Summary Publication Information The Creation of the Advisory Committee The President's Charge The Committee's Approach The Historical Context Key Findings Key Recommendations What's Next: The Advisory Committee's Legacy PUBLICATION INFORMATION The Final Report of the Advisory Committee on Human Radiation Experiments (stock number 061-000-00-848-9), the supplemental volumes to the Final Report (stock numbers 061-000-00850-1, 061-000-00851-9, and 061-000-00852-7), and additional copies of this Executive Summary (stock number 061-000-00849-7) may be purchased from the Superintendent of Documents, U.S. Government Printing Office. All telephone orders should be directed to: Superintendent of Documents

8

Office of Human Radiation Experiments - Archived Website  

NLE Websites -- All DOE Office Websites (Extended Search)

documents cold war metabolism of lethal dose studies with rates dose experiments medical research program Iodine-131 Iron-59 For further information regarding information...

9

Human Radiation Experiments: Multimedia: Film Clips  

NLE Websites -- All DOE Office Websites (Extended Search)

Film Clips Multimedia Film Clips Multimedia Home Roadmap What's New Multimedia Related Sites Feedback Sound Bytes Film Clips Historical Photographs Films require: Get Real Player 5.0 to view the films on this page. The Atom and You Second in the series The Atom and You, Paramount News, March 25, 1953, shows tests conducted at Hanford, Washington, on effects of exposure of sheep and salmon to radiation; testing of radioactive dust at UCLA laboratory; the use of radioisotopes and tracer materials for detecting cancer in patients at Oak Ridge, Tennessee; the use of rays from the cobalt source at N.Y. city’s Moncure Hospital, to treat cancer of the brain. (Time: 5 min 9 secs) Real Media Download Versions 28.8 kbps version (782k) 56.0 kbps version (1.3mb) T1 version (7.5mb) Iodine 131

10

Human Radiation Experiments: Roadmap to the Project: ACHRE Report  

NLE Websites -- All DOE Office Websites (Extended Search)

Part IV: Overview Part IV: Overview In part IV we present the overall findings of the Advisory Committee's inquiry and deliberations and the recommendations that follow from these findings. In chapter 17, findings are presented in two parts, first for the period 1944 through 1974 and then for the contemporary period. These parts, in turn, are divided into findings regarding biomedical experiments and those regarding population exposures. We begin our presentation of findings for the period 1944 through 1974 with a summation of what we have learned about human radiation experiments: their number and purpose, the likelihood that they produced harm, and how human radiation experimentation contributed to advances in medicine. We then summarize what we have found concerning the nature of federal rules and policies governing research involving human subjects during this period, and the implementation of these rules in the conduct of human radiation experiments. Findings about the nature and implementation of federal rules cover issues of consent, risk, the selection of subjects, and the role of national security considerations.

11

Advisory Committee on human radiation experiments final report  

SciTech Connect

When the Advisory Committee began work in April 1994 we were charged with determining whether the radiation experiments design and administration adequately met the ethical and scientific standards, including standards of informed consent, that prevailed at the time of the experiments and that exist today and also to determine the ethical and scientific standards and criteria by which it shall evaluate human radiation experiments. Although this charge seems straightforward, it is in fact difficult to determine what the appropriate standards should be for evaluating the conduct and policies of thirty or fifty years ago. First, we needed to determine the extent to which the standards of that time are similar to the standards of today. To the extent that there were differences we needed to determine the relative roles of each in making moral evaluations. In Chapter 1 we report what we have been able to reconstruct about government rules and policies in the 1940s and 1950s regarding human experiments. We focus primarily on the Atomic Energy Commission and the Department of Defense. In Chapter 2 we turn from a consideration of government standards to an exploration of the norms and practices of physicians and medical scientists who conducted research with human subjects during this period. Using the results of our Ethics Oral History Project, and other sources, we also examine how scientists of the time viewed their moral responsibilities to human subjects as well as how this translated into the manner in which they conducted their research.

1995-10-01T23:59:59.000Z

12

Human Radiation Experiments: What's New: Press Briefing by Secretary of  

NLE Websites -- All DOE Office Websites (Extended Search)

THE WHITE HOUSE THE WHITE HOUSE Office of the Press Secretary For Immediate Release March 28, 1997 PRESS BRIEFING BY SECRETARY OF ENERGY FEDRICO PENA, ASSISTANT SECRETARY OF ENERGY TARA O'TOOLE, AND ACTING ASSOCIATE ATTORNEY GENERAL JOHN DWYER The Briefing Room 11:10 A.M. EST MS. GLYNN: Good morning, everybody. Today we have a human radiation report here. To brief is Secretary Federico Pena; Tara O'Toole, who is the Assistant Secretary of Energy for Environment, Safety and Health; and John Dwyer, the Acting Associate Attorney General. SECRETARY PENA: Thank you very much. Good morning, everybody. Dr. O'Toole, please come up, and John, join me here to my left and right. Let me begin by reading a statement from the President and then I have an opening comment. I'll introduce Dr. O'Toole and John to make some comments.

13

Human radiation experiments associated with the US Department of Energy and its predecessors  

Science Conference Proceedings (OSTI)

This document contains a listing, description, and selected references for documented human radiation experiments sponsored, supported, or performed by the US Department of Energy (DOE) or its predecessors, including the US Energy Research and Development Administration (ERDA), the US Atomic Energy Commission (AEC), the Manhattan Engineer District (MED), and the Off ice of Scientific Research and Development (OSRD). The list represents work completed by DOE`s Off ice of Human Radiation Experiments (OHRE) through June 1995. The experiment list is available on the Internet via a Home Page on the World Wide Web (http://www.ohre.doe.gov). The Home Page also includes the full text of Human Radiation Experiments. The Department of Energy Roadmap to the Story and the Records (DOE/EH-0445), published in February 1995, to which this publication is a supplement. This list includes experiments released at Secretary O`Leary`s June 1994 press conference, as well as additional studies identified during the 12 months that followed. Cross-references are provided for experiments originally released at the press conference; for experiments released as part of The DOE Roadmap; and for experiments published in the 1986 congressional report entitled American Nuclear Guinea Pigs: Three Decades of Radiation Experiments on US Citizens. An appendix of radiation terms is also provided.

None

1995-07-01T23:59:59.000Z

14

Human Radiation Experiments: Roadmap to the Project: ACHRE Report  

NLE Websites -- All DOE Office Websites (Extended Search)

Members and Staff Acknowledgments Documentary Note Preface Introduction - The Atomic Century Part I - Ethics of Human Subjects Research: A Historical Perspective Overview...

15

Human Radiation Experiments: Roadmap to the Project: ACHRE Report  

NLE Websites -- All DOE Office Websites (Extended Search)

research involving healthy subjects: human experimentation conducted in conjunction with atomic bomb tests. More than 200,000 service personnel--now known as atomic...

16

Advisory Committee on human radiation experiments. Supplemental Volume 2a, Sources and documentation appendices. Final report  

SciTech Connect

This large document provides a catalog of the location of large numbers of reports pertaining to the charge of the Presidential Advisory Committee on Human Radiation Research and is arranged as a series of appendices. Titles of the appendices are Appendix A- Records at the Washington National Records Center Reviewed in Whole or Part by DoD Personnel or Advisory Committee Staff; Appendix B- Brief Descriptions of Records Accessions in the Advisory Committee on Human Radiation Experiments (ACHRE) Research Document Collection; Appendix C- Bibliography of Secondary Sources Used by ACHRE; Appendix D- Brief Descriptions of Human Radiation Experiments Identified by ACHRE, and Indexes; Appendix E- Documents Cited in the ACHRE Final Report and other Separately Described Materials from the ACHRE Document Collection; Appendix F- Schedule of Advisory Committee Meetings and Meeting Documentation; and Appendix G- Technology Note.

1995-01-01T23:59:59.000Z

17

Executive summary and guide to final report: Advisory committee on human radiation experiments  

SciTech Connect

On January 15, 1994, President Clinton appointed the Advisory Committee on Human Radiation Experiments to investigate reports of possibly unethical experiments funded by the government decades ago. The Committee was directed to uncover the history of human radiation experiments during the period 1944 through 1974 and to examine cases in which the government had intentionally released radiation into the environment for research purposes. The Committee was further charged with identifying the ethical and scientific standards for evaluating these events, and with making recommendations to ensure that whatever wrongdoing may have ocurred in the past cannot be repeated. The Committee undertook three projects: A review of how each agency of the federal government that currently conducts or funds research involving human subjects regulates this activity or oversees it; An examination of the documents and consent forms of research projects that are today sponsored by the federal government in order to develop insight into the current status of protections for the rights and interests of human subjects; and, Interviews of nearly 1,900 patients receiving out-patient medical care in private hospitals and federal facilities throughout the country. This booklet provides an overview of the Final Report, summarizing each chapter.

1995-01-01T23:59:59.000Z

18

Human radiation experiments: The Department of Energy roadmap to the story and the records  

SciTech Connect

The role of the US Government in conducting or sponsoring human radiation experiments has become the subject of public debate. Questions have been raised about the purpose, extent, and health consequences of these studies, and about how subjects were selected. The extent to which subjects provided informed consent is also under scrutiny. To respond to these questions, the Clinton administration has directed the US Department of Energy (DOE), along with other Federal agencies, to retrieve and inventory all records that document human radiation experiments. Many such records are now publicly available and will permit an open accounting and understanding of what took place. This report summarizes the Department`s ongoing search for records about human radiation experiments. It is also a roadmap to the large universe of pertinent DOE information. DOE is working to instill greater openness--consistent with national security and other appropriate considerations--throughout its operations. A key aspect of this effort is opening DOE`s historical records to independent research and analysis.

1995-02-01T23:59:59.000Z

19

Building Public Trust - Actions to Respond to the Report of the Advisory Committee on Human Radiation Experiments  

NLE Websites -- All DOE Office Websites (Extended Search)

B-1 B-1 Appendix B APPENDIX B ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ACCESS TO RECORDS AND INFORMATION RELATING TO HUMAN RADIATION EXPERIMENTS Advisory Committee on Human Radiation Experiments (ACHRE) Collection at the National Archives, College Park Overview: 665 cubic feet of records from the Advisory Committee on Human Radiation Experiments have been deposited at the National Archives and made part of Record Group 220, Presidential Commit- tees, Commissions, and Boards. The collection can be accessed through the Archive's Textual Reference Branch located at Archives II, 8601 Adelphi Road, College Park, Maryland. The phone number

20

Building public trust: Actions to respond to the report of the Advisory Committee on human radiation experiments  

Science Conference Proceedings (OSTI)

Democratic government requires trust: people need to know and believe that the government is telling the truth. Without information about what the government is doing and why, citizens cannot exercise democratic control over government institutions. During his first year in office, President Clinton became concerned about reports that the government had conducted unethical secret human radiation experiments during the Cold War. To address this issue, in January 1994, President Clinton established the Advisory Committee on Human Radiation Experiments (ACHRE), chaired by bioethicist Dr. Ruth Faden of Johns Hopkins University. The President also directed all Federal agencies to search for records related to human subjects radiation research and provide them to the Advisory Committee. This report presents the Administration`s actions to respond to the ACHRE`s findings and recommendations.

NONE

1997-03-01T23:59:59.000Z

Note: This page contains sample records for the topic "human radiation experiments" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


21

Building Public Trust - Actions to Respond to the Report of the Advisory Committee on Human Radiation Experiments  

NLE Websites -- All DOE Office Websites (Extended Search)

Executive Summary Executive Summary Executive Summary ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ "Our greatness is measured not only in how we . . . do right but also [in] how we act when we know we've done the wrong thing; how we confront our mistakes, make our apologies, and take action." -President Clinton October 3, 1995 In January 1994, President Clinton established the Advisory Committee on Human Radiation Experiments (ACHRE) to examine reports that the government had funded and conducted unethical human radiation experiments and releases of radiation during the

22

Advisory Committee on human radiation experiments. Final report, Supplemental Volume 2. Sources and documentation  

SciTech Connect

This volume and its appendixes supplement the Advisory Committee`s final report by reporting how we went about looking for information concerning human radiation experiments and intentional releases, a description of what we found and where we found it, and a finding aid for the information that we collected. This volume begins with an overview of federal records, including general descriptions of the types of records that have been useful and how the federal government handles these records. This is followed by an agency-by-agency account of the discovery process and descriptions of the records reviewed, together with instructions on how to obtain further information from those agencies. There is also a description of other sources of information that have been important, including institutional records, print resources, and nonprint media and interviews. The third part contains brief accounts of ACHRE`s two major contemporary survey projects (these are described in greater detail in the final report and another supplemental volume) and other research activities. The final section describes how the ACHRE information-nation collections were managed and the records that ACHRE created in the course of its work; this constitutes a general finding aid for the materials deposited with the National Archives. The appendices provide brief references to federal records reviewed, descriptions of the accessions that comprise the ACHRE Research Document Collection, and descriptions of the documents selected for individual treatment. Also included are an account of the documentation available for ACHRE meetings, brief abstracts of the almost 4,000 experiments individually described by ACHRE staff, a full bibliography of secondary sources used, and other information.

NONE

1995-01-01T23:59:59.000Z

23

Building Public Trust - Actions to Respond to the Report of the Advisory Committee on Human Radiation Experiments  

NLE Websites -- All DOE Office Websites (Extended Search)

Part 2: Protecting Future Human Subjects Part 2: Protecting Future Human Subjects Part 2: Protecting Future Human Subjects ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ Overview The success of the effort to open the historical record will be measured, in part, by whether we avoid repeating the mistakes of the past. ACHRE's review of human radiation experiments raised questions of whether the current system of protection is adequate for all types of human subjects research. The measures described below will strengthen the protection of human subjects and address ACHRE's findings. Federal responsibilities for maintaining ethics in human subjects research are dispersed in several agencies and committees in the

24

Advisory Committee on human radiation experiments. Supplemental, Volume 1, Ancillary materials. Final report  

SciTech Connect

This report is a large collection of contemporary documents pertaining to the consideration of ethical and legal aspects of use of human beings in medical and experimental studies.

1995-01-01T23:59:59.000Z

25

Radiation effects on humans  

NLE Websites -- All DOE Office Websites (Extended Search)

Radiation effects on humans Radiation effects on humans Name: Joe Kemna Location: N/A Country: N/A Date: N/A Question: I am trying to find information on radiation. I need the effects on humans, the damage it causes to the environment, and any extra information you might have on the subject. Thank you for your time. Replies: Your library should be a good place to start, but first you need to narrow your question a bit. "Radiation" means radio waves, heat, light (including the ultraviolet light that causes suntan and sunburn), and what's called "ionizing radiation." By far the major source of the first three is the Sun, while the last I believe comes principally from cosmic rays and various naturally radioactive elements like uranium and radon. The most significant manmade sources of exposure would --- I think --- be household wiring and appliances (radio), engines and heating devices (heat), lamps (light), and X-ray machines, flying at high altitude in airplanes, and living in well-insulated homes built over radon sources (ionizing radiation). Heat, light and ionizing radiation play vital roles in the ecology of the Earth. Radio, light (in particular "tanning" ultraviolet), and ionizing radiation have all been widely assumed at different times to be particularly good or particularly bad for human health. Some recent issues of public concern have been the effect of radio waves from electric transmission lines, the effect on skin cancer incidence from tanning and sunburns, the depletion of the ultraviolet-light-produced ozone in the upper atmosphere by chlorofluorocarbons (CFCs), "global warming" from the increased absorption of heat radiation from the surface by atmospheric carbon dioxide and methane, and the effect of a long exposure to low levels of ionizing radiation as for example the people of Eastern Europe are experiencing from the Chernobyl nuclear power plant accident.

26

Building Public Trust - Actions to Respond to the Report of the Advisory Committee on Human Radiation Experiments  

NLE Websites -- All DOE Office Websites (Extended Search)

Part 1: Openness in Government Part 1: Openness in Government Part 1: Openness in Government ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ Overview Throughout our nation's history, the government has needed to operate with some secrecy to protect our nation's security. At the same time, Americans have recognized that the government's power to act in secret conflicts with core democratic principles. Misuse of secrecy feeds a sense of mistrust in government that can undermine our cohesion as a nation. During the Cold War, the government funded human radiation experiments, some of which were secret. It is imperative that the public have access to the record of the government's activities. The

27

Building Public Trust - Actions to Respond to the Report of the Advisory Committee on Human Radiation Experiments  

NLE Websites -- All DOE Office Websites (Extended Search)

Part 3: Righting Past Wrongs Part 3: Righting Past Wrongs Part 3: Righting Past Wrongs ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ ○ Overview The ACHRE report reviewed in detail several case studies of government-supported human radiation research including: the injections of plutonium into 18 hospital patients during and after World War II, research with prisoners, and research on patients who were exposed to total body irradiation in clinical settings. The Advisory Committee also considered issues related to certain radiation exposures associated with government activities that the Advisory Committee concluded should not be considered "human

28

Radiation-Induced Bystander Effects and Relevance to Human Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Radiation-Induced Bystander Effects and Relevance to Human Radiation Radiation-Induced Bystander Effects and Relevance to Human Radiation Exposures Review of phenomenon appears in Radiation Research Pamela Sykes and Benjamin Blyth One concern of radiobiologists is the effect radiation exposure might have on nearby unirradiated cells. For example, when only a small fraction of cells are directly hit by radiation energy, are the surrounding unirradiated cells also at an increased risk of cancer? The term "radiation-induced bystander effect" is used to describe radiation-induced biological changes that occur in unirradiated cells within an irradiated cell population. Radiation-induced bystander effects have become established in the vernacular and are considered as an authentic radiation response. However, there is still no consensus on a precise definition of the term, which

29

The Earth Radiation Budget Experiment (ERBE)  

Science Conference Proceedings (OSTI)

The Earth Radiation Budget Experiment (ERBE) is the first multi-satellite system designed to measure the Earth's radiation budget. It will fly on a low-inclination NASA satellite and two Sun-synchronous NOAA satellites during the mid-1980s. Each ...

Bruce R. Barkstrom

1984-11-01T23:59:59.000Z

30

Human radiation studies: Remembering the early years. Oral history of Merril Eisenbud, January 26, 1995  

SciTech Connect

Merril Eisenbud was interviewed on January 26, 1995 by representatives of the US DOE Office of Human Radiation Experiments. Following a brief biographical sketch, Mr. Eisenbud relates his remembrances as the AEC`s first industrial hygienist, the setting up of AEC`s Health and Safety Laboratory, monitoring radioactive fallout, and use or exposure of humans to radiation.

1995-05-01T23:59:59.000Z

31

First Data From the Earth Radiation Budget Experiment (ERBE)  

Science Conference Proceedings (OSTI)

The first data obtained from the Earth Radiation Budget Experiment (ERBE) are presented. These data include emitted infrared radiation, albedo, and estimated scene types for 15 November 1984, as well as measurements of the solar constant. ...

ERRE Science Team

1986-07-01T23:59:59.000Z

32

The Diurnal Cycle of Outgoing Longwave Radiation from Earth Radiation Budget Experiment Measurements  

Science Conference Proceedings (OSTI)

The diurnal cycle of outgoing longwave radiation (OLR) from the earth is analyzed by decomposing satellite observations into a set of empirical orthogonal functions (EOFs). The observations are from the Earth Radiation Budget Experiment (ERBE) ...

G. Louis Smith; David A. Rutan

2003-07-01T23:59:59.000Z

33

Temperature Measurements in Radiative Shock Experiments.  

E-Print Network (OSTI)

??At signifcantly large pressures, shock waves can be driven that are so energetic that radiation starts to play an important role in the dynamics of (more)

Visco, Anthony John

2012-01-01T23:59:59.000Z

34

Low Background Radiation Experiment Yields Interesting Preliminary Results  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Low Background Radiation Experiment Yields Interesting Preliminary Low Background Radiation Experiment Yields Interesting Preliminary Results Low Background Radiation Experiment Yields Interesting Preliminary Results May 18, 2011 - 12:00pm Addthis Media Contact Deb Gill U.S. DOE Carlsbad Field Office (575) 234-7270 CARLSBAD, N.M. - New Mexico State University"s Low Background Radiation Experiment (LBRE), which takes place 2,150 feet below the earth"s surface at the Waste Isolation Pilot Plant, recently released some results about the project"s first two years of experimentation. The March 2011 edition of Health Physics printed an article titled "Exploring Biological Effects of Low Level Radiation from the Other Side of Background," summarizing some initial data taken from LBRE and from a sister experiment conducted at the Lovelace Respiratory Research Institute

35

Earth Radiation Budget Experiment (ERBE) Archival and April 1985 Results  

Science Conference Proceedings (OSTI)

This paper describes the Earth Radiation Budget Experiment (ERBE) data products being made available to the community. The Science Team used ten validation criteria to judge the acceptability of the data for archival. We list these criteria and ...

B. Barkstrom; E. Harrison; G. Smith; R. Green; J. Kibler; R. Cess; the ERBE Science Team

1989-10-01T23:59:59.000Z

36

ARM - Field Campaign - The ARM Pilot Radiation Observation Experiment...  

NLE Websites -- All DOE Office Websites (Extended Search)

govCampaignsThe ARM Pilot Radiation Observation Experiment (PROBE) Comments? We would love to hear from you Send us a note below or call us at 1-888-ARM-DATA. Send Campaign : The...

37

Radiative Corrections to the PREX and QWEAK Experiments  

SciTech Connect

The high precision parity violating electron scattering experiments PREX and QWEAK are sensitive to radiative corrections. In this paper we introduce the PREX experiment that measures the neutron radius of {sup 208}Pb and discuss coulomb distortion corrections. We then discuss dispersion corrections for QWEAK that aims to measure the weak charge of the proton.

C. J. Horowitz

2012-07-01T23:59:59.000Z

38

Radiation shielding for underground low-background experiments  

E-Print Network (OSTI)

The design task of creating an efficient radiation shield for the new COBRA double-beta decay experiment led to a comprehensive study of commercially available shielding materials. The aim was to find the most efficient combination of materials under the constraints of an extreme low-background experiment operating in a typical underground laboratory. All existing shield configurations for this type of experiment have been found to perform sub-optimally in comparison to the class of multilayered configurations proposed in this study. The method used here to create a specific shield configuration should yield a close to optimal result when applied to any experiment utilising a radiation shield. In particular, the survey of single material response to a given radiation source turns out to give a guideline for the construction of efficient multilayer shields.

D. Y Stewart; P. F. Harrison; B. Morgan; Y. A. Ramachers

2006-07-31T23:59:59.000Z

39

ARM - Field Campaign - ARM West Antarctic Radiation Experiment  

NLE Websites -- All DOE Office Websites (Extended Search)

govCampaignsARM West Antarctic Radiation Experiment govCampaignsARM West Antarctic Radiation Experiment Comments? We would love to hear from you! Send us a note below or call us at 1-888-ARM-DATA. Send Campaign : ARM West Antarctic Radiation Experiment 2015.10.01 - 2016.03.31 Lead Scientist : Dan Lubin Description West Antarctica is one of the most rapidly warming regions on Earth, and this warming is closely connected with global sea level rise. The discovery of rapid climate change on the West Antarctic Ice Sheet (WAIS) has challenged previous explanations of Antarctic climate change that focused on strengthening of circumpolar westerlies in response to the positive polarity trend in the Southern Annular Mode. West Antarctic warming does not yet have a comprehensive explanation: dynamical mechanisms may vary

40

First Estimates of the Diurnal Variation of Longwave Radiation from the Multiple-Satellite Earth Radiation Budget Experiment (ERBE)  

Science Conference Proceedings (OSTI)

First results for diurnal cycles derived from the Earth Radiation Budget Experiment (ERBE) are presented for the combined Earth Radiation Budget Satellite (ERBS) and NOAA-9 spacecraft for April 1985. Regional scale longwave (LW) radiation data ...

Edwin F. Harrison; David R. Brooks; Patrick Minnis; Bruce A. Wielicki; W. Frank Staylor; Gary G. Gibson; David F. Young; Frederick M. Denn

1988-10-01T23:59:59.000Z

Note: This page contains sample records for the topic "human radiation experiments" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


41

Human radiation studies: Remembering the early years. Oral history of Dr. George Voelz, M.D., November 29, 1994  

SciTech Connect

Dr. George Voelz was interviewed by representatives of the US DOE Office of Human Radiation Experiments (OHRE). This oral history covers Dr. Voelz`s research on Manhattan Engineering District plutonium workers, the acute and long term effects of radiation, his inhalation studies, and his activities at the 1961 INL reactor accident (SL-1 Reactor). After a brief biographical sketch, Dr. Voelz his remembrances on tissue studies of plutonium workers, the plutonium injection studies of 1945-1946, the controlled environmental radioiodine tests of 1963-1968, and tracer studies with human volunteers at Los Alamos. Dr. Voelz states his opinions concerning misconceptions about the Los Alamos Human Radiation Experiments.

1995-05-01T23:59:59.000Z

42

Radiation Analysis for the Human Lunar Return Mission  

Science Conference Proceedings (OSTI)

An analysis of the radiation hazards that are anticipated on an early Human Lunar Return (HLR) mission in support of NASA deep space exploration activities is presented. The HLR mission study emphasized a low cost lunar return to expand human capabilities ...

Wilson J. W.; Simonsen L. C.; Shinn J. L.; Dubey R. R.; Jordan W.; Kim M.

1997-09-01T23:59:59.000Z

43

Atmospheric Radiation Measurement Tropical Warm Pool International Cloud Experiment  

NLE Websites -- All DOE Office Websites (Extended Search)

Tropical Warm Pool Tropical Warm Pool International Cloud Experiment General Description The Tropical Warm Pool - International Cloud Experiment (TWP-ICE) was a collaborative effort led by the U.S. Department of Energy's Atmospheric Radiation Measurement (ARM) Program and the Australian Bureau of Meteorology. Beginning January 21 and ending February 14, 2006, the experiment was conducted in the region near the ARM Climate Research Facility in Darwin, Northern Australia. This permanent facility is fully equipped with sophisticated instruments for measuring cloud and other atmospheric properties to provide a long-term record of continuous observational data. Measurements obtained from the other experiment components (explained below) will complement this dataset to provide a detailed description of the tropical atmosphere.

44

Management of Spent and Disused Radiation Sources - The Zambian Experience  

SciTech Connect

Zambia like all other countries in the world is faced with environmental problems brought about by a variety of human activities. In Zambia the major environmental issues as identified by Nation Environmental Action Plan (NEAP) of 1994 are water pollution, poor sanitation, land degradation, air pollution, poor waste management, misuse of chemicals, wildlife depletion and deforestation. Zambian has been using a lot of radioactive materials in its various industries. The country has taken several projects with help of external partners. These partners however left these projects in the hands of the Zambians without developing their capacities to manage these radioactive sources. The Government recognized the need to manage these sources and passed legislation governing the management of radioactive materials. The first act of Parliament on Radiation Protection work was passed in 1975 to legislate the use of ionizing radiation. However, because of financial constraints the Country is facing, these regulations have remained unimplemented. Fortunately the international Community has been working in partnership with the Zambian Government in the Management of Radioactive Material. Therefore this paper will present the following aspects of radioactive waste management in Zambia: review Existing Legislation in Zambia regarding management of spent/radioactive sources; capacity building in the field of management of radioactive waste; management of spent and disused radiation sources; existing disposal systems in Zambia regarding spent/orphaned sources; existing stocks of radioactive sources in the Zambian industries.

Chabala, F.

2002-02-26T23:59:59.000Z

45

Experiment Hazard Class 7.5 - Human Tissue/Materials  

NLE Websites -- All DOE Office Websites (Extended Search)

5 - Human Tissue/Materials 5 - Human Tissue/Materials Applicability This hazard classification applies to all experiments involving biohazards requiring the use of human tissue/materials. Other hazard classifications and their associated hazard controls may also apply to experiments in this hazard class. Human tissue/materials must also be evaluated for their biosafety level and as such will have to go through the process for that particular Biosafety Level. IMPORTANT NOTE: For non-Argonne employees, all experiment protocols involving human tissue are required to be either reviewed or declared exempt from review by their home institution's Institutional Review Board (IRB). Documentation of the review should be filed in the ESAF system and with the APS BioSafety Officer (BSO) (Nena Moonier 2-8504,

46

Human radiation studies: Remembering the early years. Oral history of Julie Langham Grilly, February 3, 1995  

SciTech Connect

Julie Langham Grilly was interviewed by representatives of the US DOE Office of Human Radiation Experiments (OHRE) being the widow of Dr. Wright Langham, an investigator of principal interest of the committee. Her extensive experience with research at LANL was also of interest to the committee. Following a brief biographical sketch, Ms. Grilly relates her early postwar experience and her knowledge of Wright Langham`s involvement in animal research at Los Alamos, radiolanthanum tests on monkeys, Eniwetok tissue examinations, research on tritium uptake in humans, plutonium injections, tritium injections, EDTA, and etc. In addition to illuminating her former husband as a researcher and as an individual, she also relates her remembrances of Louis Hempelman, Enrico Fermi, Oppenheimer, Edward Teller, and many others.

1995-09-01T23:59:59.000Z

47

Human radiation studies: Remembering the early years: Oral history of pathologist Clarence Lushbaugh, M.D., conducted October 5, 1994  

SciTech Connect

This report provides a transcript of an interview with Dr. Clarance Lushbaugh by representatives of the DOE Office of Human Radiation Experiments. Dr. Lushbaugh was chosen for this interview because of his research involving experimental use of irradiation with human beings at Los Alamos and at the Oak Ridge Institute of Nuclear Science (ORINS). After a brief biographical sketch Dr. Lushbaugh and his assistant Mrs. Ann Swipe defend their use of total body irradiation using the LETBI (Low Exposure Total Body Irradiation) and the LETBI (Medium Energy Total Body Irradiator). Dr. Lushbaugh also discusses his earlier experiments involving use of nitrogen mustards in chemotherapy application, his early interest in the LD50 for man, his early impressions of low-level spray radiation as introduced by Heubline, anedotal information for his duties a pathologist for Los Alamos, and his developing interest in establishing safer radiation limits for human exposure.

1995-04-01T23:59:59.000Z

48

The CERES/ARM/GEWEX Experiment (CAGEX) for the Retrieval of Radiative Fluxes with Satellite Data  

Science Conference Proceedings (OSTI)

Results from a temporally intensive, limited area, radiative transfer model experiment are on-line for investigating the vertical profile of shortwave and longwave radiative fluxes from the surface to the top of the atmosphere (TOA). The CERES/...

Thomas P. Charlock; Timothy L. Alberta

1996-11-01T23:59:59.000Z

49

Experiments with Cloud Properties: Impact on Surface Radiative Fluxes  

Science Conference Proceedings (OSTI)

Solar radiation reaching the earths surface provides the primary forcing of the climate system, and thus, information on this parameter is needed at a global scale. Several satellite-based estimates of surface radiative fluxes are available, but ...

H. Wang; R. T. Pinker; P. Minnis; M. M. Khaiyer

2008-06-01T23:59:59.000Z

50

The Nimbus Earth Radiation Budget (ERB) Experiment: 1975 to 1992  

Science Conference Proceedings (OSTI)

Three spectrally broadband measurement sets are presently being used for earth radiation budget (ERB) studies. These are the Nimbus-6 ERB (July 1975 to June 1978), the Nimbus-7 ERB (November 1978 to the present), and the Earth Radiation Budget ...

H. L. Kyle; A. Arking; J. R. Hickey; P. E. Ardanuy; H. Jacobowitz; L. L. Stowe; G. G. Campbell; T. Vonder Haar; F. B. House; R. Maschhoff; G. L. Smith

1993-05-01T23:59:59.000Z

51

Field Experiment for Measurement of the Radiative Characteristics of a Hazy Atmosphere  

Science Conference Proceedings (OSTI)

Theoretical two-and three-dimensional solutions to the radiative transfer equation have been applied to the earth-atmosphere system. A field experiment was conducted to test this theory. in the experiment the upward radiance was measured above ...

Y. J. Kaufman; T. W. Brakke; E. Eloranta

1986-06-01T23:59:59.000Z

52

The Optical Properties of Equatorial Cirrus from Observations in the ARM Pilot Radiation Observation Experiment  

Science Conference Proceedings (OSTI)

The optical properties of equatorial cirrus were studied during a three-week period of the ARM Pilot Radiation and Observation Experiment at Kavieng, Papua New Guinea, in January and February 1993. The experiment consisted of vertical lidar (532 ...

C. M. R. Platt; S. A. Young; P. J. Manson; G. R. Patterson; S. C. Marsden; R. T. Austin; J. H. Churnside

1998-06-01T23:59:59.000Z

53

Human radiation studies: Remembering the early years. Oral history of physiologist Nello Pace, Ph.D., August 16, 1994  

SciTech Connect

Dr. Nello Pace was interviewed by representatives of the US DOE Office of Human Radiation Experiments (OHRE). Dr. Pace was selected fro the interview because of the positions he held with the US Navy, at the University of California, Berkeley, and as Director of the White Mountain Research Station near Bishop, California. Following a brief biographical sketch, Dr. Pace related his remembrances concerning tritium injections experiments in animals and humans during World War II, the development of Medical Physics Degree Programs at UC Berkeley, conducting the first radiation survey at Nagasaki after the bomb, and the establishment of a research laboratory at White Mountain. He also offers reflections on Shields Warren and comments on the public`s attitudes towards radiation both then and now.

1995-06-01T23:59:59.000Z

54

Human radiation studies: Remembering the early years: Oral history of radiation biologist Marvin Goldman, Ph.D., conducted December 22, 1994  

SciTech Connect

This report provides a transcript of an interview of Dr. Marvin Goldman by representatives of DOE`s Office of Human Radiation Experiments. Dr. Goldman was chosen for this interview because of his work on bone-seeking radionuclides. After a brief biographical sketch Dr. Goldman related his experiences concerning his training and work at Rochester University, his work at Brookhaven National Laboratory, his participation in the Beagle Studies at University of California at Davis, his work with the Chernobyl Nuclear Plant Accident, his consultation work with Russian authorities on the health and ecological effects in their history, and finally his opinions and recommendations on human radiation research and the environmental cleanup of DOE sites.

1995-09-01T23:59:59.000Z

55

Human radiation studies: Remembering the early years. Oral history of biochemist John Randolph Totter, Ph.D., January 23, 1995  

SciTech Connect

This document is a transcript of an interview of Dr. John Randolph Tottler by representatives of the US DOE Office of Human Radiation Experiments. Dr. Tottler was selected for this interview because of his career with the Atomic Energy Commission Division of Biology and Medicine (DBM), particularly as its director from 1967 to 1972. After a short biographical sketch Dr. Tottler discusses his remembrances on a wide range topics including nucleic acid and leukemia research at Oak Ridge, AEC biochemistry training in South America, DBM`s research focus on radiation effects, early leadership of DBM, relations with the US Public Health Service, controversies on low-level radiation, iodine from fallout, on John Gofman, and Project Plowshare, funding for AEC Research Programs and for international research, testicular irradiation of prisoners in Washington State and Oregon, Plutonium injections, ethics of government radiation research, and opinions of public misperceptions about radiation and cancer.

1995-09-01T23:59:59.000Z

56

EPIDEMIOLOGICAL STUDIES ON RADIATION CARCINOGENESIS IN HUMAN POPULATIONS FOLLOWING ACUTE EXPOSURE: NUCLEAR EXPLOSIONS AND MEDICAL RADIATION  

E-Print Network (OSTI)

EPIDEMIOLOGICAL STUDIES ON RADIATION CARCINOGENESIS IN HUMANEXPLOSIONS AND MEDICAL RADIATION . Jacob I. Fabrikant, MD,Low Levels of Ionizing Radiation, Yale University School of

Fabrikant, J.I.

2010-01-01T23:59:59.000Z

57

EPIDEMIOLOGICAL STUDIES ON RADIATION CARCINOGENESIS IN HUMAN POPULATIONS FOLLOWING ACUTE EXPOSURE: NUCLEAR EXPLOSIONS AND MEDICAL RADIATION  

E-Print Network (OSTI)

of the Current State of Radiation Protection Philosophy.Against Pergamon Ionizing Radiation from External Sources,for Protection Against Ionizing Radiation from Supplement to

Fabrikant, J.I.

2010-01-01T23:59:59.000Z

58

Low Dose Radiation Response Curves, Networks and Pathways in Human Lymphoblastoid Cells Exposed from 1 to 10 cGy of Acute Gamma Radiation  

E-Print Network (OSTI)

R.B. Mikkelsen, Ionizing radiation-induced, mitochondria-W.K. Rorrer, P.B. Chen, Radiation-induced proliferation ofresponse genes to ionizing radiation in human lymphoblastoid

Wyrobek, A. J.

2011-01-01T23:59:59.000Z

59

Human radiation studies: Remembering the early years. Oral history of biophysicist Cornelius A. Tobias, Ph.D., January 16, 1995  

SciTech Connect

Dr. Cornelius A. Tobias was interviewed by representatives of US DOE Office of Human Radiation Experiments (OHRE). He was chosen for this interview because of his extensive biophysics and medical physics research activities while he was employed by the University of California, Berkeley and San Francisco and at the Donner Laboratory. He discusses his involvement in wartime studies of effects of high altitude on aviators, carbon monoxide with radioactive tracers, blood studies with radioactive iron, human use committees, heavy-ion research with the Bevatron, boron isotope research, classified research involving human subjects, heavy-particle radiography, heavy- particle beams and medical research, and pituitary irradiation studies,.

1995-07-01T23:59:59.000Z

60

Human radiation studies: Remembering the early years: Oral history of radiologist Henry I. Kohn, M.D., Ph.D., conducted September 13, 1994  

SciTech Connect

This report is a transcript of an interview of Dr. Henry I. Kohn by representatives of the US DOE Office of Human Radiation Experiments. Dr. Kohn was selected for this interview because of the positions he held at Oak Ridge National Laboratory, University of California at San Francisco, and Harvard Medical School. Dr. Kohn discussed his remembrances of his experiences in blood chemistry of animals and patients exposed to radiation, and his remembrances of several radiobiologists.

1995-06-01T23:59:59.000Z

Note: This page contains sample records for the topic "human radiation experiments" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


61

Blackbody radiation-pumped CO/sub 2/ laser experiment  

Science Conference Proceedings (OSTI)

Thermal radiation from a high temperature oven was used as an optical pump to achieve lasing from CO/sub 2/ mixtures. Laser output as a function of blackbody temperature and gas conditions is described. This achievement represents the first blackbody cavity pumped laser and has potential for solar pumping.

Christiansen, W.H.; Insuik, R.J.; Deyoung, R.J.

1982-09-01T23:59:59.000Z

62

Synchrotron Radiation as X-Ray Source for EXAFS Experiments  

Science Conference Proceedings (OSTI)

Table 1   Synchrotron radiation sources...Tokyo, Japan 0.40 250 1.1 0.13 Dedicated SURF II Washington, DC 0.25 25 0.84 0.041 Dedicated Tantalus I Wisconsin 0.24 200 0.64 0.048 Dedicated PTB Braunschweig, Germany 0.14 150 0.46 0.013 Dedicated N-100 Karkhov, Soviet Union 0.10 25 0.50 0.004 ? Photon factory Tsukuba, Japan 2.5 500 8.33 4.16 Dedicated ?...

63

CRaTER: The Cosmic Ray Telescope for the Effects of Radiation Experiment on the Lunar Reconnaissance Orbiter Mission  

E-Print Network (OSTI)

The Cosmic Ray Telescope for the Effects of Radiation (CRaTER) on the Lunar Reconnaissance Orbiter (LRO) characterizes the radiation environment to be experienced by humans during future lunar missions. CRaTER measures the ...

Spence, H. E.

64

Human radiation studies: Remembering the early years. Oral history of Donner Lab Administrator Baird G. Whaley, August 15, 1994  

SciTech Connect

Baird G. Whaley, Donner Lab Administrator, was interviewed by representatives of US DOE Office of Human Radiation Experiments (OHRE). The purpose of the interview was to capture the remembrances of Mr. Whaley concerning what he could relate on activities at the Donner Lab that pertain to the OHRE responsibilities. Following a brief biographical sketch, Mr. Whaley relates his experiences in administration at the LAB including funding activities, staffing concerns, intralaboraory politics, and remembrances of John Lawrence, John Gofman, Cornelius Tobias, Jim Born, Alex Margolis, B.V.A. Low- Beer, and Ed Alpen. Further patient care procedures for Donner Clinic Research Programs were discussed.

1995-09-01T23:59:59.000Z

65

Human radiation studies: Remembering the early years. Oral history of Oncologist Helen Vodopick, M.D., December 28, 1994  

SciTech Connect

This report is a transcript of an interview with Dr. Helen Vodopick by representatives of the US DOE Office of Human Radiation Experiments. Dr. Vodopick was chosen for this interview because of her involvement with the Oak Ridge Institute of Nuclear Studies (ORINS) and Oak Ridge Associated Universities (ORAU) experimental cancer-therapy program involving total-body irradiation. After a short biographical sketch Dr. Vodopick relates her remembrances of the Medium-Exposure-Rate Total Body Irradiator (METBI), ORINS radioisotope tracer studies, treatment of cancer patients with the METBI, radiation treatment for leukemia patients, bone marrow treatment of leukemia, the Low-Exposure-Rate Total Body Irradiation (LETBI), treatment of radiation accident victims at ORAU, research with radioactive phosphorus and sulfur, and public opinion issues.

1995-08-01T23:59:59.000Z

66

Regulation of Annexin A2 by Ionizing Radiation in Human Skin...  

NLE Websites -- All DOE Office Websites (Extended Search)

Annexin A2 by Ionizing Radiation in Human Skin Equivalent Culture: Does A Nuclear Annexin A2-Protein Kinase C Epsilon Complex Contribute To Reduced Cancer Risks At Low Dose...

67

Regulation of Annexin A2 by Ionizing Radiation in Human Skin...  

NLE Websites -- All DOE Office Websites (Extended Search)

of Annexin A2 by Ionizing Radiation in Human Skin Equivalent Culture: Does A Nuclear Annexin A2-Protein Kinase C Epsilon Complex Contribute To Reduced Cancer Risks At Low...

68

Some Characteristic Differences in the Earth's Radiation Budget over Land and Ocean Derived from the Nimbus-7 ERB Experiment  

Science Conference Proceedings (OSTI)

Broad spectral band Nimbus-7 Earth Radiation Budget (ERB) experiment data are analyzed for top-of-the-atmosphere regional variations in near-ultraviolet visible and near-infrared reflected solar radiation. Regional differences in the noon vs ...

H. Lee Kyle; K. L. Vasanth

1986-07-01T23:59:59.000Z

69

REVERSE RADIATIVE SHOCK LASER EXPERIMENTS RELEVANT TO ACCRETING STREAM-DISK IMPACT IN INTERACTING BINARIES  

Science Conference Proceedings (OSTI)

We present the first results from high-energy-density laboratory astrophysics experiments that explore the hydrodynamic and radiative properties of a reverse shock relevant to a cataclysmic variable system. A reverse shock is a shock wave that develops when a freely flowing, supersonic plasma is impeded. In our experiments, performed on the Omega Laser Facility, a laser pulse is used to accelerate plasma ejecta into a vacuum. This flow is directed into an Al plate in front of which a shock forms in the rebounding plasma. The plasma flow is moving fast enough that it is shocked to high enough temperatures that radiative cooling affects the shock structure. These are the first experiments to produce a radiative reverse shock wave.

Krauland, C. M.; Drake, R. P.; Kuranz, C. C.; Huntington, C. M.; Kaczala, D. N.; Klein, S.; Sweeney, R.; Young, R. P.; Keiter, P. A. [Department of Atmospheric, Oceanic, and Space Sciences, University of Michigan, Ann Arbor, MI 48109 (United States); Loupias, B.; Falize, E.; Villette, B. [CEA-DAM-DIF, F-91297 Arpajon (France); Plewa, T., E-mail: krauland@umich.edu, E-mail: rpdrake@umich.edu [Department of Scientific Computing, Florida State University, Tallahassee, FL 32306 (United States)

2013-01-01T23:59:59.000Z

70

Acceptability of risk from radiation: Application to human space flight  

SciTech Connect

This one of NASA`s sponsored activities of the NCRP. In 1983, NASA asked NCRP to examine radiation risks in space and to make recommendations about career radiation limits for astronauts (with cancer considered as the principal risk). In conjunction with that effort, NCRP was asked to convene this symposium; objective is to examine the technical, strategic, and philosophical issues pertaining to acceptable risk and radiation in space. Nine papers are included together with panel discussions and a summary. Selected papers are indexed separately for inclusion in the Energy Science and Technology Database.

1997-04-30T23:59:59.000Z

71

EPIDEMIOLOGICAL STUDIES ON RADIATION CARCINOGENESIS IN HUMAN POPULATIONS FOLLOWING ACUTE EXPOSURE: NUCLEAR EXPLOSIONS AND MEDICAL RADIATION  

E-Print Network (OSTI)

of Atomic Bomb Radiation Effects Life Span Study Report 8.reports derive mainly from the epidemiological studies of the Japanese atomic bomb

Fabrikant, J.I.

2010-01-01T23:59:59.000Z

72

EPIDEMIOLOGICAL STUDIES ON RADIATION CARCINOGENESIS IN HUMAN POPULATIONS FOLLOWING ACUTE EXPOSURE: NUCLEAR EXPLOSIONS AND MEDICAL RADIATION  

E-Print Network (OSTI)

exposure to radioactive fallout in Radiation-Associated inIslanders, who were exposed to fallout H-bomb test explosion

Fabrikant, J.I.

2010-01-01T23:59:59.000Z

73

Quantitative Phosphoproteomics Identifies Filaggrin and other Targets of Ionizing Radiation in a Human Skin Model  

Science Conference Proceedings (OSTI)

Our objective here was to perform a quantitative phosphoproteomic study on a reconstituted human skin tissue to identify low and high dose ionizing radiation dependent signaling in a complex 3-dimensional setting. Application of an isobaric labeling strategy using sham and 3 radiation doses (3, 10, 200 cGy) resulted in the identification of 1113 unique phosphopeptides. Statistical analyses identified 151 phosphopeptides showing significant changes in response to radiation and radiation dose. Proteins responsible for maintaining skin structural integrity including keratins and desmosomal proteins (desmoglein, desmoplakin, plakophilin 1 and 2,) had altered phosphorylation levels following exposure to both low and high doses of radiation. A phosphorylation site present in multiple copies in the linker regions of human profilaggrin underwent the largest fold change. Increased phosphorylation of these sites coincided with altered profilaggrin processing suggesting a role for linker phosphorylation in human profilaggrin regulation. These studies demonstrate that the reconstituted human skin system undergoes a coordinated response to ionizing radiation involving multiple layers of the stratified epithelium that serve to maintain skin barrier functions and minimize the damaging consequences of radiation exposure.

Yang, Feng; Waters, Katrina M.; Webb-Robertson, Bobbie-Jo M.; Sowa, Marianne B.; Freiin von Neubeck, Claere H.; Aldrich, Joshua T.; Markillie, Lye Meng; Wirgau, Rachel M.; Gristenko, Marina A.; Zhao, Rui; Camp, David G.; Smith, Richard D.; Stenoien, David L.

2012-04-17T23:59:59.000Z

74

Modeling and analysis of affective influences on human experience, prediction, decision making, and behavior  

E-Print Network (OSTI)

Subjective and affective elements are well-known to influence human decision making. This dissertation presents a theoretical and empirical framework on how human decision makers' subjective experience and affective ...

Ahn, Hyungil, 1976-

2010-01-01T23:59:59.000Z

75

International RADAGAST Experiment in Niamey, Niger: Changes and Drivers of Atmospheric Radiation Balance  

Science Conference Proceedings (OSTI)

The Sahara desert is notorious as a source of massive dust storms. This dust dramatically influences the Earth-atmosphere energy budget through reflecting and absorbing the incoming sunlight. However, this budget is poorly understood, and in particular, we lack quantitative understanding of how the diurnal and seasonal variation of meteorological variables and aerosol properties influence the propagation of solar irradiance through the desert atmosphere. To improve our understanding of these influences, coincident and collocated observations of fluxes, measured from both space and the surface, are highly desirable. Recently, the unique capabilities of the African Monsoon Multidisciplinary Analysis (AMMA) Experiment, the Atmospheric Radiation Measurement (ARM) Mobile Facility (AMF), the Geostationary Earth Radiation Budget (GERB) instrument, and the Spinning Enhanced Visible and Infrared Imager (SEVIRI) were combined effectively as part of a large international project: the Radiative Atmospheric Divergence using AMF, GERB data and AMMA Stations (RADAGAST), which took place in Niamey, Niger, in 2006. The RADAGAST objectives, instrumentation, and scientific background are presented in [1]. Initial results from RADAGAST documented the strong radiative impact of a major Saharan dust storm on the Earths radiation budget [2]. A special issue of the Journal of Geophysical Research will include a collection of papers with the more complete results from RADAGAST (e.g., [1,3], and references therein). In particular, a year-long time series from RADAGAST are used to investigate (i) the factors that control the radiative fluxes and the divergence of radiation across the atmosphere [3-5], (ii) seasonal changes in the surface energy balance and associated variations in atmospheric constituents (water vapor, clouds, aerosols) [6], and (iii) sensitivity of microphysical, chemical and optical properties of aerosols to their sources and the atmospheric conditions [7]. Here we show retrievals of the aerosol properties from spectrally resolved solar measurements, the simulated and observed radiative fluxes at the surface, and outline factors that control the magnitude and variability of aerosol and radiative properties [8].

Kassianov, Evgueni I.; McFarlane, Sally A.; Barnard, James C.; Flynn, Connor J.; Slingo, A.; Bharmal, N.; Robinson, G. J.; Turner, David D.; Miller, Mark; Ackerman, Thomas P.; Miller, R.

2009-03-11T23:59:59.000Z

76

Human radiation studies: Remembering the early years. Oral history of Dr. Nadine Foreman, M.D., August 19, 1994  

SciTech Connect

Dr. Nadine Foreman was interviewed by representatives of the US DOE Office of Human Radiation Experiments (OHRE). Dr. Foreman was selected for interview because of the position she held at the University of California, San Francisco. Following a brief biographical sketch, Dr. Foreman describes her work with Dr. Mayo Soley using I-131 in treatment of hyperthyroidism, selection criteria for patients in the radioiodine project, work with Dr. Earl Miller, work at Highland Hospital, radioiodine treatment of diffuse toxic goiter (myxedema), the radiophosphorus and radioiodine programs with Dr. Bert Low-Beer, and treatment of polycythemia vera.

1995-07-01T23:59:59.000Z

77

EPIDEMIOLOGICAL STUDIES ON RADIATION CARCINOGENESIS IN HUMAN POPULATIONS FOLLOWING ACUTE EXPOSURE: NUCLEAR EXPLOSIONS AND MEDICAL RADIATION  

E-Print Network (OSTI)

Atomic Bomb by Radiation Dose, Years Research Research after Survivors, Hiroshima and Nagasaki, 1950-71 Exposure, Age,atomic bomb survivors in Hiroshima and Nagasaki (36), and the Japanese Here, 'here is an The latent age-

Fabrikant, J.I.

2010-01-01T23:59:59.000Z

78

Identification of novel ionizing radiation signaling targets in reconstituted human skin  

NLE Websites -- All DOE Office Websites (Extended Search)

of novel ionizing radiation signaling targets in reconstituted human skin of novel ionizing radiation signaling targets in reconstituted human skin Feng Yang, Katrina M. Waters, Bobbie-Jo Webb-Robertson, Lye-Meng Markillie, Rachel M. Wirgau, Shawna M. Hengel, Ljiljana Pasa-Tolic, and David L. Stenoien. Pacific Northwest National Laboratory Our focus has been on identifying the early events that occur after low dose ionizing radiation exposure that precede and often regulate downstream events such as altered transcription, protein secretion and epigenetic regulation. Phosphorylation is one of the earliest detectible events that occurs following radiation exposure and plays important roles in multiple biological pathways including DNA damage repair, transcription, apoptosis, and cell cycle progression. Very robust

79

Proteomic and Biochemical Studies of Human Mesenchymal Stem Cells in Response to Low Dose Ionizing Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Proteomic and Biochemical Studies of Human Mesenchymal Stem Cells Proteomic and Biochemical Studies of Human Mesenchymal Stem Cells in Response to Low Dose Ionizing Radiation Deok-Jin Jang 1 , Mingquan Guo 1 , Julia S.F.Chu 2 , Kyle T. Kurpinski 2 , Bjorn Rydberg 1 , Song Li 2 , and Daojing Wang 1 1. Life Sciences Division, Lawrence Berkeley National Lab, Berkeley, CA 94720 2. Department of Bioengineering, University of California, Berkeley, CA 94720 We will present data obtained during the first year of our DOE/NASA Low Dose Radiation Research program. We utilized a comprehensive approach including transcriptomics, proteomics, phosphoproteomics, and biochemistry to characterize human mesenchymal stem cells (MSCs) in response to low dose ionizing radiation. We first determined the cell survival, proliferation, and osteogenic differentiation of

80

Human radiation studies: Remembering the early years: Oral history of medical physicist Katherine L. Lathrop and physician Paul V. Harper, conducted January 26, 1995  

SciTech Connect

This report provides a transcript of an interview with Ms. Katherine L. Lathrop and Dr. Paul V. Hopper by representatives of the DOE Office of Human Radiation Research. Ms. Lathrop and Dr. Hopper were chosen for this interview because of their long-standing interest and research experience in the development of nuclear medicine. After brief biographical sketches the researchers provide a broad and interesting description of their roles in the initial uses of many radiopharmaceuticals, their experiences in human experimentation, and interactions with many other pioneers in nuclear medicine.

1995-09-01T23:59:59.000Z

Note: This page contains sample records for the topic "human radiation experiments" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


81

Experiences with collaborative, distributed predictive human performance modeling  

Science Conference Proceedings (OSTI)

Although predictive human performance modeling has been researched for 30 years in HCI, to our knowledge modeling has been conducted as a solitary task of one modeler or, occasionally, two modelers working in tight face-to-face collaboration. In contrast, ... Keywords: cogtool, efficiency, klm, predictive human performance modeling, usability evaluation

Bonnie John; Sonal Starr; Brian Utesch

2012-05-01T23:59:59.000Z

82

Experiences from measuring human mobility using Bluetooth inquiring devices  

Science Conference Proceedings (OSTI)

We present an analysis of human mobility measurements using Bluetooth devices. A number of data traces from such measurements have been made publicly available for the benefit of the research community. However, the limitations of the measurement approaches ... Keywords: Bluetooth, data traces, experimentation, human mobility, opportunistic networking

Erik Nordstrm; Christophe Diot; Richard Gass; Per Gunningberg

2007-06-01T23:59:59.000Z

83

Recent Chemical Decontamination Experience: 2012 Radiation Management and Source Term Technical Strategy Group Report  

Science Conference Proceedings (OSTI)

Chemical decontamination remains a viable option for nuclear power plants to reduce radiation levels during maintenance and operating activities. This report presents the results of recent system chemical decontamination experiences from EPRI-member utilities in the United States and Europe, collected through an industry survey and as part of participation in the EPRI BWR Chemistry Monitoring and Assessment Program.BackgroundSome plants have performed ...

2013-06-19T23:59:59.000Z

84

The children of parents exposed to atomic bombs: Estimates of the genetic doubling dose of radiation for humans  

SciTech Connect

The data collected in Hiroshima and Nagasaki during the past 40 years on the children of survivors of the atomic bombings and on the children of a suitable control population are analyzed on the basis of the newly revised estimates of radiation doses. No statistically significant effects emerge with respect to eight different indicators. Since, however, it may confidently be assumed some mutations were induced, we have taken the data at face value and calculated the minimal gametic doubling doses of acute radiation for the individual indicators at various probability levels. An effort has also been made to calculate the most probable doubling dose for the indicators combined. The latter value is between 1.7 and 2.2 Sv. It is suggested the appropriate figure for chronic radiation would be between 3.4 and 4.5 Sv. These estimates suggest humans are less sensitive to the genetic effects of radiation than has been assumed on the basis of past extrapolations from experiments with mice.

Neel, J.V.; Schull, W.J.; Awa, A.A.; Satoh, C.; Kato, H.; Otake, M.; Yoshimoto, Y. (Univ. of Michigan Medical School, Ann Arbor (USA))

1990-06-01T23:59:59.000Z

85

Human radiation studies: Remembering the early years: Oral history of biochemist William D. Moss, conducted November 30, 1994  

SciTech Connect

This report is a transcript of an interview with William D. Moss by representatives of the US DOE Office of Human Radiation Experiments. Mr. Moss was selected for this interview because of his work at Los Alamos National Laboratory concerning analytical methods in the chemical determination of plutonium in biological materials. After a brief biographical sketch, Mr. Moss relates his understanding of how occupational exposure limits were determined for the Manhattan Project, how data from those workers who were exposed to plutonium was collected and analyzed, how the experiments were planned and data was gathered from plutonium or polonium injections in man, how problems with analytical procedures compounded health physics aspects of the project, and problems remaining in the interpretation of these data.

1995-09-01T23:59:59.000Z

86

Entrepreneurial experiments in science policy: Analyzing the Human Genome Project  

E-Print Network (OSTI)

We re-conceptualize the role of science policy makers, envisioning and illustrating their move from being simple investors in scientific projects to entrepreneurs who create the conditions for entrepreneurial experiments ...

Huang, Kenneth G.

87

The influence of microwave radiation on the state of chromatin in human cells  

E-Print Network (OSTI)

Isolated human buccal epithelium cell were irradiated by microwaves at frequency f=35 GHz and surface power density E=30 mcW/cm2. The state of chromatin in human cells was determined by methodsof light and electron microscopy. The state of cell membranes was evaluated by the method of vital indigo carmine staining. The microwave-induced condensation of chromatin in human cells was revealed. Left side circulary polarized waves induced less effect than linearly polarized radiation. The linearly polarized electromagnetic waves induced cell membrane damage revealed by the increase of cell stainability. The data obtained are discussed in connection with the mechanisms of biologica effect of electromagnetic waves.

Shckorbatov, Y G; Grabina, V A; Kolchigin, N N; Batrakov, D O; Kalashnikov, V V; Ivanchenko, D D; Bykov, V N

2008-01-01T23:59:59.000Z

88

The influence of microwave radiation on the state of chromatin in human cells  

E-Print Network (OSTI)

Isolated human buccal epithelium cell were irradiated by microwaves at frequency f=35 GHz and surface power density E=30 mcW/cm2. The state of chromatin in human cells was determined by methodsof light and electron microscopy. The state of cell membranes was evaluated by the method of vital indigo carmine staining. The microwave-induced condensation of chromatin in human cells was revealed. Left side circulary polarized waves induced less effect than linearly polarized radiation. The linearly polarized electromagnetic waves induced cell membrane damage revealed by the increase of cell stainability. The data obtained are discussed in connection with the mechanisms of biologica effect of electromagnetic waves.

Y. G. Shckorbatov; V. N. Pasiuga; V. A. Grabina; N. N. Kolchigin; D. O. Batrakov; V. V. Kalashnikov; D. D. Ivanchenko; V. N. Bykov

2008-09-03T23:59:59.000Z

89

Bayesian inference of inaccuracies in radiation transport physics from inertial confinement fusion experiments  

E-Print Network (OSTI)

First principles microphysics models are essential to the design and analysis of high energy density physics experiments. Using experimental data to investigate the underlying physics is also essential, particularly when simulations and experiments are not consistent with each other. This is a difficult task, due to the large number of physical models that play a role, and due to the complex (and as a result, noisy) nature of the experiments. This results in a large number of parameters that make any inference a daunting task; it is also very important to consistently treat both experimental and prior understanding of the problem. In this paper we present a Bayesian method that includes both these effects, and allows the inference of a set of modifiers which have been constructed to give information about microphysics models from experimental data. We pay particular attention to radiation transport models. The inference takes into account a large set of experimental parameters and an estimate of the prior kno...

Gaffney, Jim A; Sonnad, Vijay; Libby, Stephen B

2013-01-01T23:59:59.000Z

90

Measuring the effects of online advertising on human behavior using natural and field experiments  

E-Print Network (OSTI)

This thesis investigates the effects of online advertising on human behavior: clicks, new-account sign-ups, and retail sales. Five chapters cover natural and field experiments used to measure these effects for both display ...

Lewis, Randall A. (Randall Aaron)

2010-01-01T23:59:59.000Z

91

Electroweak Radiative Corrections to the Parity-violating Asymmetry for SLAC Experiment E158  

SciTech Connect

Electroweak radiative corrections to observable quantities of Moeller scattering of polarized particles are calculated. We emphasize the contribution induced by infrared divergent parts of cross section. The covariant method is used to remove infrared divergences, so that our results do not involve any unphysical parameters. When applied to the kinematics of SLAC E158 experiment, these corrections reduce the parity violating asymmetry by about -6.5% at E = 48 GeV and y = 0.5, and kinematically weighted 'hard' bremsstrahlung effect for SLAC E158 is {approx} 1%.

Zykunov, Vladimir A.; /Gomel State Tech. U.

2012-04-04T23:59:59.000Z

92

Neutron Fluences and Radiation Damage Parameters for the HFIR-MFE-RB-17J Experiment  

Science Conference Proceedings (OSTI)

The HFIR-MFE-RB-17J experiment was conducted in the removable beryllium (RB) position of HFIR with a Eu2O2 shield. The irradiation was conducted from April 27, 2004, to May 18, 2005. The total exposure was for 353.6 FPD (full power days). Reactor dosimetry capsules were analyzed and the activation data were used to provide the best estimates of the neutron fluences and radiation damage parameters as a function of height relative to midplane of the reactor.

Greenwood, Lawrence R.; Glasgow, David C.; Baldwin, Charles A.

2010-06-30T23:59:59.000Z

93

Neutron Fluences and Radiation Damage Parameters for the HFIR-MFE-RB-14J Experiment  

Science Conference Proceedings (OSTI)

The HFIR-MFE-RB-14J experiment was conducted in the unshielded removable beryllium (RB) position of HFIR. The irradiation of the assembly occurred for two separated time periods. The first irradiation was from June 3, 1999 to August 27, 1999. The second irradiation period was from January 27, 2000 until June 6, 2000. The total exposure was for 14293 FPD (full power days). Reactor dosimetry capsules were analyzed and the activation data were used to provide the best estimates of the neutron fluences and radiation damage parameters as a function of height relative to midplane of the reactor.

Greenwood, Lawrence R.; Glasgow, David C.; Baldwin, Charles A.

2010-08-23T23:59:59.000Z

94

Neutron Fluences and Radiation Damage Parameters for the HFIR-MFE-RB-17J Experiment  

Science Conference Proceedings (OSTI)

The HFIR-MFE-RB-17J experiment was conducted in the removable beryllium (RB) position of HFIR with a Eu2O2 shield. The irradiation was conducted from April 27, 2004, to May 18, 2005. The total exposure was for 353.6 FPD (full power days). Reactor dosimetry capsules were analyzed and the activation data were used to provide the best estimates of the neutron fluences and radiation damage parameters as a function of height relative to midplane of the reactor.

Greenwood, Lawrence R.; Glasgow, David C.; Baldwin, Charles A.

2010-08-23T23:59:59.000Z

95

Neutron Fluences and Radiation Damage Parameters for the HFIR-MFE-RB-14J Experiment  

Science Conference Proceedings (OSTI)

The HFIR-MFE-RB-14J experiment was conducted in the unshielded removable beryllium (RB) position of HFIR. The irradiation of the assembly occurred for two separated time periods. The first irradiation was from June 3, 1999 to August 27, 1999. The second irradiation was from January 27, 2000 until June 6, 2000. The total exposure was for 14293 FPD (full power days). Reactor dosimetry capsules were analyzed and the activation data were used to provide the best estimates of the neutron fluences and radiation damage parameters as a function of height relative to midplane of the reactor.

Greenwood, Lawrence R.; Glasgow, David C.; Baldwin, Charles A.

2010-06-30T23:59:59.000Z

96

Evaluating human-robot interaction during a manipulation experiment conducted in immersive virtual reality  

Science Conference Proceedings (OSTI)

This paper presents the main highlights of a Human-Robot Interaction (HRI) study conducted during a manipulation experiment performed in Cave Automatic Virtual Environment (CAVE). Our aim is to assess whether using immersive Virtual Reality (VR) for ... Keywords: CAVE, human-robot interaction, immersive virtual reality, manipulation, presence

Mihai Duguleana; Florin Grigorie Barbuceanu; Gheorghe Mogan

2011-07-01T23:59:59.000Z

97

Genome Wide Evaluation of Normal Human Tissue in Response to Controlled, In vivo Low-Dose Low LET Ionizing Radiation Exposure: Pathways and Mechanisms Final Report, September 2013  

SciTech Connect

During course of this project, we have worked in several areas relevant to low-dose ionizing radiation. Using gene expression to measure biological response, we have examined the response of human skin exposed in-vivo to radation, human skin exposed ex-vivo to radiation, and a human-skin model exposed to radiation. We have learned a great deal about the biological response of human skin to low-dose ionizing radiation.

Rocke, David M. [University of California Davis

2013-09-09T23:59:59.000Z

98

Thermal correction to the Casimir force, radiative heat transfer, and an experiment  

E-Print Network (OSTI)

The low-temperature asymptotic expressions for the Casimir interaction between two real metals described by Leontovich surface impedance are obtained in the framework of thermal quantum field theory. It is shown that the Casimir entropy computed using the impedance of infrared optics vanishes in the limit of zero temperature. By contrast, the Casimir entropy computed using the impedance of the Drude model attains at zero temperature a positive value which depends on the parameters of a system, i.e., the Nernst heat theorem is violated. Thus, the impedance of infrared optics withstands the thermodynamic test, whereas the impedance of the Drude model does not. We also perform a phenomenological analysis of the thermal Casimir force and of the radiative heat transfer through a vacuum gap between real metal plates. The characterization of a metal by means of the Leontovich impedance of the Drude model is shown to be inconsistent with experiment at separations of a few hundred nanometers. A modification of the impedance of infrared optics is suggested taking into account relaxation processes. The power of radiative heat transfer predicted from this impedance is several times less than previous predictions due to different contributions from the transverse electric evanescent waves. The physical meaning of low frequencies in the Lifshitz formula is discussed. It is concluded that new measurements of radiative heat transfer are required to find out the adequate description of a metal in the theory of electromagnetic fluctuations.

V. B. Bezerra; G. Bimonte; G. L. Klimchitskaya; V. M. Mostepanenko; C. Romero

2007-08-18T23:59:59.000Z

99

Overview of observations from the RADAGAST experiment in Niamey, Niger. Part 2: Radiative fluxes and divergences  

SciTech Connect

Broadband shortwave and longwave radiative fluxes observed both at the surface and from space during the RADAGAST experiment in Niamey, Niger in 2006 are presented. The surface fluxes were measured by the Atmospheric Radiation Measurement (ARM) Program Mobile Facility (AMF) at Niamey airport, while the fluxes at the top of the atmosphere (TOA) are from the Geostationary Earth Radiation Budget (GERB) instrument on the Meteosat-8 satellite. The data are analyzed as daily averages, in order to minimise sampling differences between the surface and top of atmosphere instruments, while retaining the synoptic and seasonal changes that are the main focus of this study. A cloud mask is used to identify days with cloud from those with predominantly clear skies. The influence of temperature, water vapor, aerosols and clouds is investigated. Aerosols are ubiquitous throughout the year and have a significant impact on both the shortwave and longwave fluxes. The large and systematic seasonal changes in temperature and column integrated water vapor (CWV) through the dry and wet seasons are found to exert strong influences on the longwave fluxes. These influences are often in opposition to each other, because the highest temperatures occur at the end of the dry season when the CWV is lowest, while in the wet season the lowest temperatures are associated with the highest values of CWV. Apart from aerosols, the shortwave fluxes are also affected by clouds and by the seasonal changes in CWV. The fluxes are combined to provide estimates of the divergence of radiation across the atmosphere throughout 2006. The longwave divergence is remarkably constant through the year, because of a compensation between the seasonal variations in the outgoing longwave radiation (OLR) and surface net longwave radiation. A simple model of the greenhouse effect is used to interpret this result in terms of the dependence of the normalized greenhouse effect at the TOA and of the effective emissivity of the atmosphere at the surface on the CWV. It is shown that, as the CWV increases, the atmosphere loses longwave energy to the surface with about the same increasing efficiency with which it traps the OLR, thus keeping the atmospheric longwave divergence roughly constant. The shortwave divergence is mainly determined by the CWV and aerosol loadings and the effect of clouds is much smaller than on the component fluxes.

Slingo, A.; White, H. E.; Bharmal, N.; Robinson, G. J.

2009-02-25T23:59:59.000Z

100

Human radiation studies: Remembering the early years. Oral history of hematologist Karl F. Hubner, M.D., December 30, 1994  

SciTech Connect

This report is a transcript of an interview of Dr. Karl F. Hubner by representatives of the US DOE Human Radiation Experiments. Dr. Hubner was selected for this interview because of his participation in the Oak Ridge Institute of Nuclear Studies(ORINS)/Oak Ridge Associated Universities(ORAU) Medical Division cancer therapy research program involving total body irradiation. After a short biographical sketch Dr. Hubner discusses his research in Bone Marrow Transplants, his participation in the development of Nuclear Medicine in Oak Ridge, use of the total body irradiation machine at the University of Tennessee School of Agriculture Animal Research Laboratory (later the Comparative Animal Research Laboratory or CARL) to deliver a high enough dose rate to destroy a patients immune system, the operation of a sterile environment for recovery of patients following bone- marrow transplantation, and the closing of the ORAU Medical Division`s Clinical Program following a negative review. Finally, Dr. Hubner describes his later research using PET.

1995-09-01T23:59:59.000Z

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101

{sub p}53-Dependent Adaptive Responses in Human Cells Exposed to Space Radiations  

Science Conference Proceedings (OSTI)

Purpose: It has been reported that priming irradiation or conditioning irradiation with a low dose of X-rays in the range of 0.02-0.1 Gy induces a p53-dependent adaptive response in mammalian cells. The aim of the present study was to clarify the effect of space radiations on the adaptive response. Methods and Materials: Two human lymphoblastoid cell lines were used; one cell line bears a wild-type p53 (wtp53) gene, and another cell line bears a mutated p53 (mp53) gene. The cells were frozen during transportation on the space shuttle and while in orbit in the International Space Station freezer for 133 days between November 15, 2008 and March 29, 2009. After the frozen samples were returned to Earth, the cells were cultured for 6 h and then exposed to a challenging X-ray-irradiation (2 Gy). Cellular sensitivity, apoptosis, and chromosome aberrations were scored using dye-exclusion assays, Hoechst33342 staining assays, and chromosomal banding techniques, respectively. Results: In cells exposed to space radiations, adaptive responses such as the induction of radioresistance and the depression of radiation-induced apoptosis and chromosome aberrations were observed in wtp53 cells but not in mp53 cells. Conclusion: These results have confirmed the hypothesis that p53-dependent adaptive responses are apparently induced by space radiations within a specific range of low doses. The cells exhibited this effect owing to space radiations exposure, even though the doses in space were very low.

Takahashi, Akihisa [Department of Biology, School of Medicine, Nara Medical University, Nara (Japan); Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency, Ibaraki (Japan); Su Xiaoming [Department of Biology, School of Medicine, Nara Medical University, Nara (Japan); Suzuki, Hiromi [Japan Space Forum, Tokyo (Japan); Space Environmental Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima (Japan); Omori, Katsunori [Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency, Ibaraki (Japan); Seki, Masaya; Hashizume, Toko [Space Environmental Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima (Japan); Advanced Engineering Services Company, Limited, Ibaraki (Japan); Shimazu, Toru [Japan Space Forum, Tokyo (Japan); Ishioka, Noriaki [Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency, Ibaraki (Japan); Space Environmental Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima (Japan); Iwasaki, Toshiyasu [Radiation Safety Research Center, Nuclear Technology Research Laboratory, Central Research Institute of the Electric Power Industry of Japan, Tokyo (Japan); Ohnishi, Takeo, E-mail: tohnishi@naramed-u.ac.j [Department of Radiation Oncology, School of Medicine, Nara Medical University, Nara (Japan); Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency, Ibaraki (Japan)

2010-11-15T23:59:59.000Z

102

Human radiation studies: Remembering the early years. Oral history of Dr. John W. Gofman, M.D., Ph.D., December 20, 1994  

SciTech Connect

Dr. John W. Gofman was interviewed by representatives of US DOE Office of Human Radiation Experiments (OHRE) concerning his research at the University of California, Berkeley and his biomedical work at Lawrence Livermore Radiation Laboratory. Following a short biographical sketch, Dr. Gofman relates his remembrances with the discovery and chemistry of uranium-233, the Manhattan project, laboratory production of the first milligram of plutonium, pre-1945 medical use of high-dosage radiation, medical treatments with phosphorus 32, and fallout. Dr. Gofman also discusses his relationships with Professor Oppenheimer, Joe Hamilton, Ernest Lawrence, and other. Then Dr. Gofman describes his pioneering work on his true interests concerning heart disease, heparin, and lipoproteins. Finally intra-AEC political issues are discussed relating to testing of atomic weapons.

1995-06-01T23:59:59.000Z

103

Human radiation studies: Remembering the early years: Oral history of radiologist Hymer L. Friedell, M.D., Ph.D., conducted January 28, 1995  

SciTech Connect

NThis report is a transcript of an interview with Hymer L. Friedell by representatives of the US DOE Office of Human Radiation Experiments. Dr. Friedell was selected for this interview because of his participation in the early stages of the medical use of radioisotopes, his important role in the Manhattan Engineer District Medical Division, and his distinguished medical career and his involvement in the distribution of isotopes and the approval for their use in humans. After a brief biographical sketch Dr. Friedell discusses his remembrances on a wide range of subjects. Topics discussed include pre-war radiation therapy, information provided to patients, the Army Medical Corps and the Manhattan Project, his work at the Chicago Metallurgical Laboratory, inspection visits of Manhattan Project facilities and proposed sites, Plutonium injection studies, and actions of the AEC Isotope Distribution Committee.

Fisher, D.; Melamed, E.

1995-07-01T23:59:59.000Z

104

Radiosensitization of Human Cervical Cancer Cells by Inhibiting Ribonucleotide Reductase: Enhanced Radiation Response at Low-Dose Rates  

Science Conference Proceedings (OSTI)

Purpose: To test whether pharmacologic inhibition of ribonucleotide reductase (RNR) by 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP, NSC no. 663249) enhances radiation sensitivity during low-dose-rate ionizing radiation provided by a novel purpose-built iridium-192 cell irradiator. Methods and Materials: The cells were exposed to low-dose-rate radiation (11, 23, 37, 67 cGy/h) using a custom-fabricated cell irradiator or to high-dose-rate radiation (330 cGy/min) using a conventional cell irradiator. The radiation sensitivity of human cervical (CaSki, C33-a) cancer cells with or without RNR inhibition by 3-AP was evaluated using a clonogenic survival and an RNR activity assay. Alteration in the cell cycle distribution was monitored using flow cytometry. Results: Increasing radiation sensitivity of both CaSki and C33-a cells was observed with the incremental increase in radiation dose rates. 3-AP treatment led to enhanced radiation sensitivity in both cell lines, eliminating differences in cell cytotoxicity from the radiation dose rate. RNR blockade by 3-AP during low-dose-rate irradiation was associated with low RNR activity and extended G{sub 1}-phase cell cycle arrest. Conclusions: We conclude that RNR inhibition by 3-AP impedes DNA damage repair mechanisms that rely on deoxyribonucleotide production and thereby increases radiation sensitivity of human cervical cancers to low-dose-rate radiation.

Kunos, Charles A., E-mail: charles.kunos@UHhospitals.org [Department of Radiation Oncology, University Hospitals Case Medical Center and Case Western Reserve School of Medicine, Cleveland, OH (United States); Colussi, Valdir C. [Department of Radiation Oncology, University Hospitals Case Medical Center and Case Western Reserve School of Medicine, Cleveland, OH (United States); Pink, John [Department of General Medical Sciences, University Hospitals Case Medical Center and Case Western Reserve School of Medicine, Cleveland, OH (United States); Radivoyevitch, Tomas [Department of Epidemiology and Biostatistics, Case Comprehensive Cancer Center, University Hospitals Case Medical Center and Case Western Reserve School of Medicine, Cleveland, OH (United States); Oleinick, Nancy L. [Department of Radiation Oncology, University Hospitals Case Medical Center and Case Western Reserve School of Medicine, Cleveland, OH (United States)

2011-07-15T23:59:59.000Z

105

Ionizing radiation downregulates ASPM, a gene responsible for microcephaly in humans  

SciTech Connect

Microcephaly is a malformation associated with in utero exposed atomic bomb survivors and can be induced in mice by fetal exposure to ionizing radiation (IR). The pathogenesis of IR-induced microcephaly, however, has not been fully understood. Our analyses of high-coverage expression profiling (HiCEP) demonstrated that the abnormal spindle-like microcephaly associated gene (ASPM) was down-regulated in irradiated human diploid fibroblasts. ASPM was recently reported as the causative gene for MCPH-5, the most common type of congenital microcephaly in humans. Here, we show that the expression of the Aspm gene was significantly reduced by IR in various human and murine cells. Additionally, Aspm was found downregulated in the irradiated fetal mouse brain, particularly in the ventricular zones. A similar suppression was observed in the irradiated neurosphere cultures. This is the first report suggesting that the suppression of Aspm by IR could be the initial molecular target leading to the future microcephaly formation.

Fujimori, Akira [Cellular and Molecular Biology Team, National Institute of Radiological Sciences, Heavy-Ion Radiobiology Research Group, Research Center for Charged Particle Therapy, 4-9-1 Anagawa, Inage, Chiba 263-8555 (Japan)], E-mail: fujimora@nirs.go.jp; Yaoi, Takeshi; Ogi, Hiroshi [Department of Pathology and Applied Neurobiology, Kyoto Prefectural University of Medicine, Graduate School of Medical Sciences, Kawaramachi Hirokoji, Kamigyo-ku, Kyoto 602-8566 (Japan); Wang Bing [National Institute of Radiological Sciences, Heavy-Ion Radiology Research Group, Research Center for Charged Particle Therapy, 4-9-1 Anagawa, Inage, Chiba 263-8555 (Japan); Suetomi, Katsutoshi; Sekine, Emiko; Yu Dong; Kato, Takamitsu [Cellular and Molecular Biology Team, National Institute of Radiological Sciences, Heavy-Ion Radiobiology Research Group, Research Center for Charged Particle Therapy, 4-9-1 Anagawa, Inage, Chiba 263-8555 (Japan); Takahashi, Sentaro [National Institute of Radiological Sciences, Heavy-Ion Radiology Research Group, Research Center for Charged Particle Therapy, 4-9-1 Anagawa, Inage, Chiba 263-8555 (Japan); Okayasu, Ryuichi [Cellular and Molecular Biology Team, National Institute of Radiological Sciences, Heavy-Ion Radiobiology Research Group, Research Center for Charged Particle Therapy, 4-9-1 Anagawa, Inage, Chiba 263-8555 (Japan); Itoh, Kyoko; Fushiki, Shinji [Department of Pathology and Applied Neurobiology, Kyoto Prefectural University of Medicine, Graduate School of Medical Sciences, Kawaramachi Hirokoji, Kamigyo-ku, Kyoto 602-8566 (Japan)

2008-05-09T23:59:59.000Z

106

Human radiation studies: Remembering the early years: Oral history of health physicist Constantine J. Maletskos, Ph.D., conducted January 20, 1995  

SciTech Connect

This report is a transcript of an interview with Dr. Constatine J. Maletskos by representatives of the DOE Office of Human Radiation Experiments. Dr. Maletskos was selected for this interview because of his research at the Radioactivity Center of the Massachusetts Institute of Technology (MIT), at the Harvard Medical School, and at the New England Deaconess Hospital. After a brief biographical sketches Dr. Maletskos discusses at length about his work at the Center on research that used subjects from the Walter E. Fernald State School in Waverly, Massachusetts and the New England Center for Aging, as well as blood volume work involving pregnant women. He further discusses his work with radium Dial Painters, his work with Dr. Robley Evans, and various other subjects concerning experiments with human subjects under the auspices of the AEC.

1995-09-01T23:59:59.000Z

107

Human radiation studies: Remembering the early years: Oral history of physician James S. Robertson, M.D., Ph.D., conducted January 20, 1995  

SciTech Connect

This report is a transcript of in interview of Dr. James S. Robertson by representatives of the DOE Office of Human Radiation Experiments. Dr. Robertson was chosen for this interview because of his research at Brookhaven National Laboratory, especially on Boron Neutron Capture Therapy (BNCT); his work at the United States Naval Defense Laboratory; and his work at the Atomic Energy Commission. After a brief biographical sketch Dr. Robertson discusses research on human subjects at Berkeley, his contributions to the beginnings of Neutron Capture Therapy at Brookhaven, his participation with the Brookhaven Human Use Committee, his involvement in the study of the effects of Castle Bravo event on the Marshallese, and his work with the Naval Radiological Defense Laboratory.

1995-09-01T23:59:59.000Z

108

Human radiation studies: Remembering the early years. Oral history of Health physicist William J. Bair, Ph.D., October 14, 1994  

SciTech Connect

This report is a transcript of an interview of William J. Blair by representatives of the US DOE Office of Human Radiation Experiments. Dr. Blair was selected for this interview because of of his participation in the University of Rochester Atomic Energy Project and for his radiological inhalation research at Hanford Site. After a brief biographical sketch Dr. Blair discusses his remembrances on a wide rage of topics. Discussions include his graduate studies at Rochester University, use of human subjects at Rochester, his inhalation studies, his limited involvement with human studies, differing biological effects of plutonium 238 and 239, emissions from proposed nuclear-propelled aircraft, cancer research, cleanup at Nevada Test Site and Marshall Islands, impact of Langham studies to understand Plutonium exposure, and AEC controversies and colleagues.

Harrell, D.; Shindledecker, C.

1995-06-01T23:59:59.000Z

109

Human radiation studies: Remembering the early years: Oral history of cell biologist Don Francis Petersen, Ph.D., conducted November 29, 1994  

SciTech Connect

This report is a transcript of an interview of Dr. Don Francis Petersen by representatives of the US DOE Office of Human Radiation Experiments. Dr. Petersen was selected for this interview because of his long research career at Los Alamos and his knowledge of the Atomic Energy Commission`s biomedical program. Dr. Petersen did not personally conduct research on human subjects. After a brief biographical sketch Dr. Petersen discusses his remembrances of the early use of radionuclides as biological tracers, aspects of nuclear weapons testing in the 1940`s and 1950`s including fallout studies, the means by which research projects were approved, use of humans in the whole-body counter, and the Health Division Biomedical responsibilities.

1995-08-01T23:59:59.000Z

110

The Baseline Surface Radiation Network Pyrgeometer Round-Robin Calibration Experiment  

Science Conference Proceedings (OSTI)

With the aim of improving the consistency of terrestrial and atmospheric longwave radiation measurements within the Baseline Surface Radiation Network, five Eppley Precision Infrared Radiometer (PIR) pyrgeometers and one modified Meteorological ...

Rolf Philipona; Claus Frhlich; Klaus Dehne; John DeLuisi; John Augustine; Ellsworth Dutton; Don Nelson; Bruce Forgan; Peter Novotny; John Hickey; Steven P. Love; Steven Bender; Bruce McArthur; Atsumu Ohmura; John H. Seymour; John S. Foot; Masataka Shiobara; Francisco P. J. Valero; Anthony W. Strawa

1998-06-01T23:59:59.000Z

111

Metabolomic Response of Human Skin Tissue to Low Dose Ionizing Radiation  

Science Conference Proceedings (OSTI)

Understanding how human organs respond to ionizing radiation (IR) at a systems biology level and identifying biomarkers for IR exposure at low doses can help provide a scientific basis for establishing radiation protection standards. Little is known regarding the physiological responses to low dose IR at the metabolite level, which represents the end-point of biochemical processes inside cells. Using a full thickness human skin tissue model and GC-MS-based metabolomics analysis, we examined the metabolic perturbations at three time points (3, 24 and 48 hr) after exposure to 3, 10 and 200 cGy of X-rays. PLS-DA score plots revealed dose- and time-dependent clustering between sham and irradiated groups. Importantly, a comparable number of metabolites were detected to have significant change 48 hr after exposure to 3 and 10 cGy of irradiation, when compared with the high dose of 200 cGy. Biochemical pathway analysis showed perturbations to DNA/RNA damage and repair, lipid and energy metabolisms, even at low doses of IR.

Hu, Zeping; Kim, Young-Mo; Sowa, Marianne B.; Robinson, Robert J.; Gao, Xiaoli; Metz, Thomas O.; Morgan, William F.; Zhang, Qibin

2012-05-18T23:59:59.000Z

112

Human radiation studies: Remembering the early years: Oral history of health physicist Karl Z. Morgan, Ph.D., conducted January 7, 1995  

SciTech Connect

This report provided a transcript of an interview of Dr. Karl. Z. Morgan by representatives of the DOE Office of Human Radiation Experiments. Dr. Morgan was selected for this interview because of his research for the Manhattan Project at the Metallurgical Laboratory in Chicago and his work at the Oak Ridge National Laboratory (ORNL). The oral history covers Dr. Morgan`s work as a pioneer in the field of Health Physics, his research at ORNL and his work since he retired from ORNL.

1995-06-01T23:59:59.000Z

113

Beta Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Beta Radiation 1. Beta radiation may travel meters in air and is moderately penetrating. 2. Beta radiation can penetrate human skin to the "germinal layer," where new skin cells...

114

Design of experiments to observe radiation stabilized Rayleigh-Taylor instability growth at an embedded decelerating interface  

Science Conference Proceedings (OSTI)

Using a hohlraum produced thermal x-ray drive at the National Ignition Facility (NIF) to create pressure by material ablation, a shock exceeding 200 Mbar can be driven through a planar, solid-density target and into a lower-density foam material. The shock driven through the foam is strongly radiative, and this radiation significantly alters the dynamics of the system, including those of the Rayleigh-Taylor (RT) fluid instability at the interface between the two materials. We discuss here the design of experiments that can produce such radiative conditions. One will be able to compare the observed growth rates with an extensive body of hydrodynamic experiments performed previously. In this paper, we describe a set of 1D simulations performed to understand the mechanisms of stabilization in a strongly radiative Rayleigh-Taylor unstable system. Simulation results are used to calculate modified analytic RT growth rates which have been proposed in the literature. Calculations predict reduced RT spike growth as a result of increases in density gradient scale length and mass ablation from the unstable interface. This work has direct applicability to the observable features in upcoming NIF experiments.

Huntington, C. M.; Kuranz, C. C.; Drake, R. P. [AOSS, University of Michigan, Ann Arbor, Michigan 48103 (United States); Miles, A. R.; Prisbrey, S. T.; Park, H.-S.; Robey, H. F.; Remington, B. A. [Lawrence Livermore National Laboratory, Livermore, California 94550 (United States)

2011-11-15T23:59:59.000Z

115

Radiators  

SciTech Connect

A heat-exchange radiator is connected to a fluid flow circuit by a connector which provides one member of an interengageable spigot and socket pair for push-fit, fluid-tight, engagement between the connector and the radiator, with latching formations at least one of which is resilient. Preferably the connector carries the spigot which tapers and engages with a socket of corresponding shape, the spigot carrying an O-ring seal and either latching fingers or a resilient latching circlip.

Webster, D. M.

1985-07-30T23:59:59.000Z

116

Alterations in transcription factor binding in radioresistant human melanoma cells after ionizing radiation  

Science Conference Proceedings (OSTI)

We analyzed alterations in transcription factor binding to specific, known promoter DNA consensus sequences between irradiated and unirradiated radioresistant human melanoma (U1-Mel) cells. The goal of this study was to begin to investigate which transcription factors and DNA-binding sites are responsible for the induction of specific transcripts and proteins after ionizing radiation. Transcription factor binding was observed using DNA band-shift assays and oligonucleotide competition analyses. Confluence-arrested U1-Mel cells were irradiated (4.5 Gy) and harvested at 4 h. Double-stranded oligonucleotides containing known DNA-binding consensus sites for specific transcription factors were used. Increased DNA binding activity after ionizing radiation was noted with oligonucleotides containing the CREB, NF-kB and Sp1 consensus sites. No changes in protein binding to AP-1, AP-2, AP-3, or CTF/NF1, GRE or Oct-1 consensus sequences were noted. X-ray activation of select transcription factors, which bind certain consensus sites in promoters, may cause specific induction or repression of gene transcription. 22 refs., 2 figs.

Sahijdak, W.M.; Yang, Chin-Rang; Zuckerman, J.S.; Meyers, M.; Boothman, D.A. [Univ. of Wisconsin, Madison, WI (United States)

1994-04-01T23:59:59.000Z

117

Low Dose Radiation Response Curves, Networks and Pathways in Human Lymphoblastoid Cells Exposed from 1 to 10 cGy of Acute Gamma Radiation  

Science Conference Proceedings (OSTI)

We investigated the low dose dependency of the transcriptional response of human cells to characterize the shape and biological functions associated with the dose response curve and to identify common and conserved functions of low dose expressed genes across cells and tissues. Human lymphoblastoid (HL) cells from two unrelated individuals were exposed to graded doses of radiation spanning the range of 1-10 cGy were analyzed by transcriptome profiling, qPCR and bioinformatics, in comparison to sham irradiated samples. A set of {approx}80 genes showed consistent responses in both cell lines; these genes were associated with homeostasis mechanisms (e.g., membrane signaling, molecule transport), subcellular locations (e.g., Golgi, and endoplasmic reticulum), and involved diverse signal transduction pathways. The majority of radiation-modulated genes had plateau-like responses across 1-10 cGy, some with suggestive evidence that transcription was modulated at doses below 1 cGy. MYC, FOS and TP53 were the major network nodes of the low-dose response in HL cells. Comparison our low dose expression findings in HL cells with those of prior studies in mouse brain after whole body exposure, in human keratinocyte cultures, and in endothelial cells cultures, indicates that certain components of the low dose radiation response are broadly conserved across cell types and tissues, independent of proliferation status.

Wyrobek, A. J.; Manohar, C. F.; Nelson, D. O.; Furtado, M. R.; Bhattacharya, M. S.; Marchetti, F.; Coleman, M.A.

2011-04-18T23:59:59.000Z

118

Transport, Radiative, and Dynamical Effects of the Antarctic Ozone Hole: A GFDL SKYHI Model Experiment  

Science Conference Proceedings (OSTI)

The GFDL SKYHI general circulation model has been used to simulate the effect of the Antarctic ozone hole phenomenon on the radiative and dynamical environment of the lower stratosphere. Both the polar ozone destruction and photochemical ...

J. D. Mahlman; L. J. Umscheid; J. P. Pinto

1994-02-01T23:59:59.000Z

119

Experiences from First Top-Off Injection at the Stanford Synchrotron Radiation Lightsource  

Science Conference Proceedings (OSTI)

As the Stanford Synchrotron Radiation Lightsource (SSRL) of the SLAC National Accelerator Laboratory (SLAC) is moving toward Top-Off injection mode, SLAC's Radiation Protection Department is working with SSRL on minimizing the radiological hazards of this mode. One such hazard is radiation that is created inside the accelerator concrete enclosure by injected beam. Since during Top-Off injection the stoppers that would otherwise isolate the storage ring from the experimental area stay open, the stoppers no longer prevent such radiation from reaching the experimental area. The level of this stray radiation was measured in April 2008 during the first Top-Off injection tests. They revealed radiation dose rates of up to 18 microSv/h (1.8 millirem/h) outside the experimental hutches, significantly higher than our goal of 1 microSv/h (0.1 millirem/h). Non-optimal injection increased the measured dose rates by a factor two. Further tests in 2008 indicated that subsequent improvements by SSRL to the injection system have reduced the dose rates to acceptable levels. This presentation describes the studies performed before the Top-Off tests, the tests themselves and their major results (both under initial conditions and after improvements were implemented), and presents the controls being implemented for full and routine Top-Off injection.

Bauer, J.M.; Liu, J.C.; Prinz, A.; Rokni, S.H.; /SLAC

2009-12-11T23:59:59.000Z

120

Low Dose Radiation Research Program: Image Gallery  

NLE Websites -- All DOE Office Websites (Extended Search)

Image Gallery Image Gallery These are images, photographs, and charts presented or developed for Low Dose Radiation Research Investigators’ Meetings. They may be used for presentations or reports. To save, right click on the picture, then choose "Save picture as." U.S. annual per-capita effective radiation dose from various sources for 1980. various sources 1980 Enlarge Image. U.S. annual per-capita effective radiation dose from various sources for 2006. various sources 2006 Enlarge Image. U.S. annual per-capita effective radiation dose from man-made sources in the United States for 2006. man-made 2006 Enlarge Image. Ionizing Radiation Dose Ranges showing the wide range of radiation doses that humans experience (Rem) Enlarge Image. Ionizing Radiation Dose Ranges showing the wide range of radiation doses that humans experience

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121

Improved radiative corrections to (e,e{sup '}p) experiments: Explicit treatment of kinematical corrections in multiphoton bremsstrahlung  

SciTech Connect

Radiative processes lead to important corrections to (e,e{sup '}p) experiments. While radiative corrections can be calculated exactly in QED and to a good accuracy also including hadronic corrections, these corrections cannot be included into data analyses to arbitrary orders exactly. Nevertheless consideration of multiphoton bremsstrahlung above the low-energy cutoff is important for many (e,e{sup '}p) experiments. To date, higher-order bremsstrahlung effects concerning electron scattering experiments have been implemented approximately by employing the soft-photon approximation (SPA). In this paper we propose a novel approach to multiphoton emission which partially removes the SPA from (e,e{sup '}p) experiments. In this combined approach one hard photon is treated exactly; and additional (softer) bremsstrahlung photons are taken into account resorting to the soft-photon approximation. This partial removal of the soft-photon approximation is shown to be relevant for the missing-energy distribution for several kinematic settings at MAMI and TJNAF energies.

Weissbach, Florian [GSI Helmholtzzentrum fuer Schwerionenforschung mbH, D-64291 Darmstadt (Germany); Departement fuer Physik, Universitaet Basel, CH-4056 Basel (Switzerland); Hencken, Kai [Departement fuer Physik, Universitaet Basel, CH-4056 Basel (Switzerland); ABB Schweiz AG, Corporate Research, CH-5405 Baden-Daettwil (Switzerland); Kiselev, Daniela [Departement fuer Physik, Universitaet Basel, CH-4056 Basel (Switzerland); Paul Scherrer Institut, CH-5232 Villigen (Switzerland); Trautmann, Dirk [Departement fuer Physik, Universitaet Basel, CH-4056 Basel (Switzerland)

2009-08-15T23:59:59.000Z

122

Ionizing Radiation Activates AMP-Activated Kinase (AMPK): A Target for Radiosensitization of Human Cancer Cells  

SciTech Connect

Purpose: Adenosine monophosphate (AMP)-activated kinase (AMPK) is a molecular energy sensor regulated by the tumor suppressor LKB1. Starvation and growth factors activate AMPK through the DNA damage sensor ataxia-telangiectasia mutated (ATM). We explored the regulation of AMPK by ionizing radiation (IR) and its role as a target for radiosensitization of human cancer cells. Methods and Materials: Lung, prostate, and breast cancer cells were treated with IR (2-8 Gy) after incubation with either ATM or AMPK inhibitors or the AMPK activator metformin. Then, cells were subjected to either lysis and immunoblotting, immunofluorescence microscopy, clonogenic survival assays, or cell cycle analysis. Results: IR induced a robust phosphorylation and activation of AMPK in all tumor cells, independent of LKB1. IR activated AMPK first in the nucleus, and this extended later into cytoplasm. The ATM inhibitor KU-55933 blocked IR activation of AMPK. AMPK inhibition with Compound C or anti-AMPK {alpha} subunit small interfering RNA (siRNA) blocked IR induction of the cell cycle regulators p53 and p21{sup waf/cip} as well as the IR-induced G2/M arrest. Compound C caused resistance to IR, increasing the surviving fraction after 2 Gy, but the anti-diabetic drug metformin enhanced IR activation of AMPK and lowered the surviving fraction after 2 Gy further. Conclusions: We provide evidence that IR activates AMPK in human cancer cells in an LKB1-independent manner, leading to induction of p21{sup waf/cip} and regulation of the cell cycle and survival. AMPK appears to (1) participate in an ATM-AMPK-p21{sup waf/cip} pathway, (2) be involved in regulation of the IR-induced G2/M checkpoint, and (3) may be targeted by metformin to enhance IR responses.

Sanli, Toran; Rashid, Ayesha; Liu Caiqiong [Department of Oncology, Juravinski Cancer Center and McMaster University, Hamilton, Ontario (Canada)

2010-09-01T23:59:59.000Z

123

Alpha Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Basics of Radiation Basics of Radiation Gamma Radiation and X-Rays Beta Radiation Alpha Radiation Irradiation Radioactive Contamination Definitions Detection Measurement Safety Around Radiation Sources Types of Radiation Exposure Managing Radiation Emergencies Basics of Radiation Characteristics of Alpha Radiation 1. Alpha radiation is not able to penetrate skin. 2. Alpha-emitting materials can be harmful to humans if the materials are inhaled, swallowed, or absorbed through open wounds. 3. A variety of instruments have been designed to measure alpha radiation. Special training in use of these instruments is essential for making accurate measurements. 4. A civil defense instrument (CD V-700) cannot detect the presence of radioactive materials that produce alpha radiation unless the radioactive materials also produce beta and/or gamma radiation.

124

Human Impact on Direct and Diffuse Solar Radiation during the Industrial Era  

Science Conference Proceedings (OSTI)

In this study the direct and diffuse solar radiation changes are estimated, and they contribute to the understanding of the observed global dimming and the more recent global brightening during the industrial era. Using a multistream radiative ...

Maria M. Kvalevg; Gunnar Myhre

2007-10-01T23:59:59.000Z

125

Ionizing radiation induces IL-6-production by human fibroblasts involving activation of nuclear factor-. kappa. B  

Science Conference Proceedings (OSTI)

The authors report that human lung fibroblasts respond to X-ray treatment with release of interleukin (IL) -6. Synthesis of IL-6 upon ionizing radiation is preceded by an increase of IL-6 transcript levels resulting from transcriptional activation of the IL-6 gene. Analysis of deleted fragments of the IL-6 promoter revealed that transcriptional induction of the IL-6 promoter is due to enhanced binding activity of the transcription factor NF-kB. Although AP-1 does not participate in the rapid induction of the IL-6 promoter its binding activity is also enhanced upon XRT. In contrast to binding kinetics observed with NF-kB, AP-1 binding upon XRT. In contrast to binding kinetics observed with NF-kB- and the AP-1 recognition sequence, conferred inducibility by XRT to a heterologous promoter, with reporter gene activity being maximal 24 hours or 48 hours upon XRT, respectively. Sequential activation of two distinct transcription factors might thus contribute to synchronize transcriptional activation of different genes participating in the X-ray response.

Brach, M.A.; Gruss, H.J.; Kaisho, Tsuneyasu; Asano, Yoshinobu; Vos, Sven de; Mertelsmann, R.; Hirano, Toshio; Herrmann, F. (Univ. of Freiburg (Germany) Osaka Univ. (Japan))

1992-02-26T23:59:59.000Z

126

Comments to "Comparison of two experiments on radiative neutron decay" by R.U.Khafizov et al., published in Physics of Atomic Nuclei  

E-Print Network (OSTI)

Some critical comments and remarks on the article "Comparison of two experiments on radiative neutron decay" by R.U.Khafizov et al., published in Physics of Atomic Nuclei.

Kuznetsov, I A

2010-01-01T23:59:59.000Z

127

Comments to "Comparison of two experiments on radiative neutron decay" by R.U.Khafizov et al., published in Physics of Atomic Nuclei  

E-Print Network (OSTI)

Some critical comments and remarks on the article "Comparison of two experiments on radiative neutron decay" by R.U.Khafizov et al., published in Physics of Atomic Nuclei.

I. A. Kuznetsov

2010-06-22T23:59:59.000Z

128

Human factors in telemanipulation: Perspectives from the Oak Ridge National Laboratory experience  

SciTech Connect

Personnel at the Robotics and Process Systems Division (RPSD) of the Oak Ridge National Laboratory (ORNL) have extensive experience designing, building, and operating teleoperators for a variety of settings, including space, battlefields, nuclear fuel reprocessing plants, and hazardous waste retrieval. In the course of the last decade and a half, the RPSD designed, built, and operated 4 telemanipulators (M-2, ASM, LTM, CESAR arm) and operated another half dozen (M-8, Model 50, TOS SM-229, RM-10, PaR 5000, BilArm 83A). During this period, human factors professionals have been closely integrated with RPSD design teams, investigating telemanipulator feedback and feed forward, designing cockpits and control rooms, training users and designers, and helping to develop performance specifications for telemanipulators. This paper presents a brief review of this and other work, with an aim towards providing perspectives on some of the human factors aspects of telemanipulation. The first section of the paper examines user tasks during supervisory control and discusses how telemanipulator responsiveness determines the appropriate control metaphor for continuous manual control. The second section provides an ecological perspective on telemanipulator feedback and feed-forward. The third section briefly describes the RPSD control room design approach and how design projects often serve as systems integrators.

Draper, J.V.

1994-01-01T23:59:59.000Z

129

A revised model for radiation dosimetry in the human gastrointestinal tract  

E-Print Network (OSTI)

A new model for an adult human gastrointestinal tract (GIT) has been developed for use in internal dose estimations to the wall of the GIT and to the other organs and tissues of the body from radionuclides deposited in the lumenal contents of the five sections of the GIT. These sections were the esophagus, stomach, small intestine, upper large intestine, and the lower large intestine. The wall of each section was separated from its lumenal contents. Each wall was divided into many small regions so that the histologic and radiosensitive variations of the tissues across the wall could be distinguished. The characteristic parameters were determined based on the newest information available in the literature. Each of these sections except the stomach was subdivided into multiple subsections to include the spatiotemporal variations in the shape and characteristic parameters. This new GIT was integrated into an anthropomorphic phantom representing both an adult male and a larger-than-average adult female. The current phantom contains 14 different types of tissue. This phantom was coupled with the MCNP 4C Monte Carlo simulation package. The initial design and coding of the phantom and the Monte Carlo treatment employed in this study were validated using the results obtained by Cristy and Eckerman (1987). The code was used for calculating specific absorbed fractions (SAFs) in various organs and radiosensitive tissues from uniformly distributed sources of fifteen monoenergetic photons and electrons, 10 keV - 4 MeV, in the lumenal contents of the five sections of the GIT. The present studies showed that the average photon SAFs to the walls were significantly different from that to the radiosensitive cells (stem cells) for the energies below 50 keV. Above 50 keV, the photon SAFs were found to be almost constant across the walls. The electron SAF at the depth of the stem cells was a small fraction of the SAF routinely estimated at the contents-mucus interface. Electron studies showed that the self-dose for the energies below 300 keV and the cross-dose below 2 MeV were only from bremsstrahlung and fluorescent radiations at the depth of the stem cells and were not important.

Bhuiyan, Md. Nasir Uddin

2003-08-01T23:59:59.000Z

130

Plasma density from Cerenkov radiation, betatron oscillations, and beam steering in a plasma wakefield experiment at 30 GeV  

E-Print Network (OSTI)

Gearhart,Construction of a Cerenkov light source, Rev.Plasma density from Cerenkov radiation, betatroncal considerations in the use of Cerenkov radiation as an

2001-01-01T23:59:59.000Z

131

A Radiation-Hydrodynamics Code Comparison for Laser-Produced Plasmas: FLASH versus HYDRA and the Results of Validation Experiments  

E-Print Network (OSTI)

The potential for laser-produced plasmas to yield fundamental insights into high energy density physics (HEDP) and deliver other useful applications can sometimes be frustrated by uncertainties in modeling the properties and expansion of these plasmas using radiation-hydrodynamics codes. In an effort to overcome this and to corroborate the accuracy of the HEDP capabilities recently added to the publicly available FLASH radiation-hydrodynamics code, we present detailed comparisons of FLASH results to new and previously published results from the HYDRA code used extensively at Lawrence Livermore National Laboratory. We focus on two very different problems of interest: (1) an Aluminum slab irradiated by 15.3 and 76.7 mJ of "pre-pulse" laser energy and (2) a mm-long triangular groove cut in an Aluminum target irradiated by a rectangular laser beam. Because this latter problem bears a resemblance to astrophysical jets, Grava et al., Phys. Rev. E, 78, (2008) performed this experiment and compared detailed x-ray int...

Orban, Chris; Chawla, Sugreev; Wilks, Scott C; Lamb, Donald Q

2013-01-01T23:59:59.000Z

132

LET dependence of radiation-induced bystander effects using human prostate tumor cells  

E-Print Network (OSTI)

In the past fifteen years, evidence provided by many independent research groups have indicated higher numbers of cells exhibiting damage than expected based on the number of cells traversed by the radiation. This phenomenon ...

Anzenberg, Vered

2008-01-01T23:59:59.000Z

133

Activation of nuclear factor kB in human lymphoblastoid cells by low-dose ionizing radiation  

SciTech Connect

Nuclear factor kB (NF-kB) is a pleiotropic transcription factor which is involved in the transcriptional regulation of several specific genes. Recent reports demonstrated that ionizing radiation in the dose range of 2-50 Gy results in expression of NF-kB in human KG-1 myeloid leukemia cells and human B-lymphocyte precursor cells; the precise mechanism involved and the significance are not yet known. The present report demonstrates that even lower doses of ionizing radiation, 0.25-2.0 Gy, are capable of inducing expression of NF-kB in EBV-transformed 244B human lymphoblastoid cells. These results are in a dose range where the viability of the cells remains very high. After exposure to {sup 137}Cs {gamma} rays at a dose rate of 1.17 Gy/min, a maximum in expression of NF-kB was seen at 8 h after a 0.5-Gy exposure. Time-course studies revealed a biphasic time-dependent expression after 0.5-, 1- and 2-Gy exposures. However, for each time examined, the expression of NF-kB was maximum after the 0.5-Gy exposure. The expression of the p50 and p65 NF-kB subunits was also shown to be regulated differentially after exposures to 1.0 and 2.0 Gy. 32 refs., 3 figs.

Prasad, A.V.; Mohan, N.; Meltz, M.L.; Chandrasekar, B. [Univ. of Texas Health Science Center, San Antonio, TX (United States)

1994-06-01T23:59:59.000Z

134

Estimates of Radiation Exposures for Human Crews in Deep Space from the January 15, 2005, Solar Energetic Particle Event Using the Earth-Moon-Mars Radiation Environment Module  

Science Conference Proceedings (OSTI)

Technical Paper / Special Issue on the 16th Biennial Topical Meeting of the Radiation Protection and Shielding Division / Radiation Transport and Protection

Mahmoud PourArsalan; Lawrence W. Townsend; Nathan A. Schwadron; Kamen Kozarev; Maher A. Dayeh; Mihir I. Desai

135

CicLAvia and Human Infrastructure in Los Angeles: Ethnographic Experiments in Equitable Bike Planning  

E-Print Network (OSTI)

Health: The Role of Infrastructure. Journal of Public HealthP. , Bell, G. , 2007. The Infrastructure of Experience andthe Experience of Infrastructure: Meaning and Structure in

Lugo, Adonia E.

2013-01-01T23:59:59.000Z

136

Application of 3-dimensional radiation transport codes to the analysis of the CRBR prototypic coolant pipe chaseway neutron streaming experiment  

Science Conference Proceedings (OSTI)

This report summarizes the calculational results from analyses of a Clinch River Breeder Reactor (CRBR) prototypic coolant pipe chaseway neutron streaming experiment Comparisons of calculated and measured results are presented, major emphasis being placed on results at bends in the chaseway. Calculations were performed with three three-dimensional radiation transport codes: the discrete ordinates code TORT and the Monte Carlo code MORSE, both developed by the Oak Ridge National Laboratory (ORNL), and the discrete ordinates code ENSEMBLE, developed by Japan. The calculated results from the three codes are compared (1) with previously-calculated DOT3.5 two-dimensional results, (2) among themselves, and (3) with measured results. Calculations with TORT used both the weighted-difference and nodal methods. Only the weighted-difference method was used in ENSEMBLE. When the calculated results were compared to measured results, it was found that calculation-to-experiment (C/E) ratios were good in the regions of the chaseway where two-dimensional modeling might be difficult and where there were no significant discrete ordinates ray effects. Excellent agreement was observed for responses dominated by thermal neutron contributions. MORSE-calculated results and comparisons are described also, and detailed results are presented in an appendix.

Chatani, K. (Power Reactor and Nuclear Development Corp., Experimental Reactor Div., Ibaraki (Japan))

1992-08-01T23:59:59.000Z

137

Experiences  

NLE Websites -- All DOE Office Websites (Extended Search)

Experiences Experiences with 100Gbps Network Applications Mehmet Balman, Eric Pouyoul, Yushu Yao, E. Wes Bethel Burlen Loring, Prabhat, John Shalf, Alex Sim, and Brian L. Tierney Lawrence Berkeley National Laboratory One Cyclotron Road Berkeley, CA, 94720, USA {mbalman,epouyoul,yyao,ewbethel,bloring,prabhat,jshalf,asim,btierney}@lbl.gov ABSTRACT 100Gbps networking has finally arrived, and many research and educational institutions have begun to deploy 100Gbps routers and services. ESnet and Internet2 worked together to make 100Gbps networks available to researchers at the Supercomputing 2011 con- ference in Seattle Washington. In this paper, we describe two of the first applications to take advantage of this network. We demon- strate a visualization application that enables remotely located sci- entists to gain insights from large datasets. We also demonstrate climate

138

Energy spectrum and mass composition of primary cosmic radiation in the region above the knee from the GAMMA experiment  

E-Print Network (OSTI)

The energy spectrum of the primary cosmic radiation in the energy range 1 - 100 PeV and the extensive air shower (EAS) characteristics obtained on the basis of the expanded data bank of the GAMMA experiment (Mt. Aragats, Armenia) are presented. With increased statistics we confirm our previous results on the energy spectrum. The spectral index above the knee is about -3.1, but at energies beyond 20 PeV a flattening of the spectrum is observed. The existence of the 'bump' at about 70 PeV is confirmed with a significance of more than 4{\\sigma}. In the energy range of 10 - 100 PeV the shower age becomes energy independent and we observe a direct proportionality of the EAS size to the primary energy. This suggests an approximately constant depth of the EAS maximum in this energy range. This is evidence in favour of an increasing average mass of primary particles at energies above 20 PeV. The additional source scenario, which is a possible explanation of the 'bump' in the spectrum, also leads to the conclusion of ...

Martirosov, R M; Vardanyan, H S; Erlykin, A D; Nikolskaya, N M; Gallant, Y A; Jones, L W; Babayan, H A

2012-01-01T23:59:59.000Z

139

Evaluation of the mechanical properties of human liver and kidney through aspiration experiments  

Science Conference Proceedings (OSTI)

A proper mechanical characterization of soft biological tissues of the human body has a strong impact on several medical applications such as surgical planning, virtual reality simulators, trauma research, and for diagnostic purposes. Adequate experimental ...

Alessandro Nava; Edoardo Mazza; Frederic Kleinermann; Nick J. Avis; John McClure; Michael Bajka

2004-08-01T23:59:59.000Z

140

Protein Kinase CK2 Regulates Cytoskeletal Reorganization during Ionizing Radiation-Induced Senescence of Human Mesenchymal Stem Cells  

SciTech Connect

Human mesenchymal stem cells (hMSC) are critical for tissue regeneration. How hMSC respond to genotoxic stresses and potentially contribute to aging and cancer remain underexplored. We demonstrated that ionizing radiation induced cellular senescence of hMSC over a period of 10 days, showing a critical transition between day 3 and day 6. This was confirmed by senescence-associated beta-galactosidase (SA-{beta}-gal) staining, protein expression profiles of key cell cycle regulators (retinoblastoma (Rb) protein, p53, p21{sup waf1/Cip1}, and p16{sup INK4A}), and senescence-associated secretory phenotypes (SASPs) (IL-8, IL-12, GRO, and MDC). We observed dramatic cytoskeletal reorganization of hMSC through reduction of myosin-10, redistribution of myosin-9, and secretion of profilin-1. Using a SILAC-based phosphoproteomics method, we detected significant reduction of myosin-9 phosphorylation at Ser1943, coinciding with its redistribution. Importantly, through treatment with cell permeable inhibitors (4,5,6,7-tetrabromo-1H-benzotriazole (TBB) and 2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole (DMAT)), and gene knockdown using RNA interference, we identified CK2, a kinase responsible for myosin-9 phosphorylation at Ser1943, as a key factor contributing to the radiation-induced senescence of hMSC. We showed that individual knockdown of CK2 catalytic subunits CK2{alpha} and CK2{alpha}{prime} induced hMSC senescence. However, only knockdown of CK2{alpha} resulted in morphological phenotypes resembling those of radiation-induced senescence. These results suggest that CK2{alpha} and CK2{alpha}{prime} play differential roles in hMSC senescence progression, and their relative expression might represent a novel regulatory mechanism for CK2 activity.

Wang, Daojing; Jang, Deok-Jin

2009-08-21T23:59:59.000Z

Note: This page contains sample records for the topic "human radiation experiments" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


141

Parameter Sweep Experiments on Spontaneous Gravity Wave Radiation from Unsteady Rotational Flow in an f-Plane Shallow Water System  

Science Conference Proceedings (OSTI)

Inertial gravity wave radiation from an unsteady rotational flow (spontaneous radiation) is investigated numerically in an f-plane shallow water system for a wide range of Rossby numbers, 1 ? Ro ? 1000, and Froude numbers, 0.1 ? Fr ? 0.8. A ...

Norihiko Sugimoto; Keiichi Ishioka; Katsuya Ishii

2008-01-01T23:59:59.000Z

142

THE NATIONAL CENTER FOR RADIOECOLOGY: A NETWORK OF EXCELLENCE FOR ENVIRONMENTAL AND HUMAN RADIATION RISK REDUCTION  

SciTech Connect

Radioecology in the United States can be traced back to the early 1950s when small research programs were established to address the fate and effects of radionuclides released in the environment from activities at nuclear facilities. These programs focused primarily on local environmental effects, but global radioactive fallout from nuclear weapons testing and the potential for larger scale local releases of radioisotopes resulted in major concerns about the threat, not only to humans, but to other species and to ecosystems that support all life. These concerns were shared by other countries and it was quickly recognized that a multi-disciplinary approach would be required to address and understand the implications of anthropogenic radioactivity in the environment. The management, clean-up and long-term monitoring of legacy wastes at Department of Energy (DOE), Department of Defense (DOD), and Nuclear Regulatory Commission (NRC)-regulated facilities continues to be of concern as long as nuclear operations continue. Research conducted through radioecology programs provides the credible scientific data needed for decision-making purposes. The current status of radioecology programs in the United States are: fragmented with little coordination to identify national strategies and direct programs; suffering from a steadily decreasing funding base; soon to be hampered by closure of key infrastructure; hampered by aging and retiring workforce (loss of technical expertise); and in need of training of young scientists to ensure continuation of the science (no formal graduate education program in radioecology remaining in the U.S.). With these concerns in mind, the Savannah River National Laboratory (SRNL) took the lead to establish the National Center for Radioecology (NCoRE) as a network of excellence of the remaining radioecology expertise in the United States. As part of the NCoRE mission, scientists at SRNL are working with six key partner universities to re-establish a graduate education training program for radioecology. Recently, NCoRE hosted a workshop to identify the immediate needs for science-driven discoveries, tool development and the generation of scientific data to support the legislative decision-making process for remediation strategies, long-term monitoring of radiologically-contaminated sites and protection of human health and the environment. Some of the immediate strategic research needs were identified in the fields of functional genomics for determining low-dose effects, improved low-level dosimetry, and mixed (radiological and chemical) contaminant studies. Longer term strategic research and tool development areas included development of radioecology case study sites, comprehensive decision-making tools, consequence response actions, and optimized scenario based ecosystem modeling. A summary of the NCoRE workshop findings related to waste management needs and priority areas will be presented in this paper.

Jannik, T.

2013-01-09T23:59:59.000Z

143

Structural Stability of Human Fibroblast Growth Factor-1 Is Essential for Protective Effects Against Radiation-Induced Intestinal Damage  

Science Conference Proceedings (OSTI)

Purpose: Human fibroblast growth factor-1 (FGF1) has radioprotective effects on the intestine, although its structural instability limits its potential for practical use. Several stable FGF1 mutants were created increasing stability in the order, wild-type FGF1, single mutants (Q40P, S47I, and H93G), Q40P/S47I, and Q40P/S47I/H93G. This study evaluated the contribution of the structural stability of FGF1 to its radioprotective effect. Methods and Materials: Each FGF1 mutant was administered intraperitoneally to BALB/c mice in the absence of heparin 24 h before or after total body irradiation (TBI) with {gamma}-rays at 8-12 Gy. Several radioprotective effects were examined in the jejunum. Results: Q40P/S47I/H93G could activate all subtypes of FGF receptors in vitro much more strongly than the wild-type without endogenous or exogenous heparin. Preirradiation treatment with Q40P/S47I/H93G significantly increased crypt survival more than wild-type FGF1 after TBI at 10 or 12 Gy, and postirradiation treatment with Q40P/S47I/H93G was effective in promoting crypt survival after TBI at 10, 11, or 12 Gy. In addition, crypt cell proliferation, crypt depth, and epithelial differentiation were significantly promoted by postirradiation treatment with Q40P/S47I/H93G. The level of stability of FGF1 mutants correlated with their mitogenic activities in vitro in the absence of heparin; however, preirradiation treatment with the mutants increased the crypt number to almost the same level as Q40P/S47I/H93G. When given 24 h after TBI at 10 Gy, all FGF1 mutants increased crypt survival more than wild-type FGF1, and Q40P/S47I/H93G had the strongest mitogenic effects in intestinal epithelial cells after radiation damage. Moreover, Q40P/S47I/H93G prolonged mouse survival after TBI because of the repair of intestinal damage. Conclusion: These findings suggest that the structural stability of FGF1 can contribute to the enhancement of protective effects against radiation-induced intestinal damage. Therefore, Q40P/S47I/H93G is pharmacologically one of the most promising candidates for clinical applications for radiation-induced gastrointestinal syndrome.

Nakayama, Fumiaki, E-mail: f_naka@nirs.go.jp [Advanced Radiation Biology Research Program, Research Center for Charged Particle Therapy, National Institute of Radiological Sciences, Chiba (Japan)] [Advanced Radiation Biology Research Program, Research Center for Charged Particle Therapy, National Institute of Radiological Sciences, Chiba (Japan); Umeda, Sachiko [Advanced Radiation Biology Research Program, Research Center for Charged Particle Therapy, National Institute of Radiological Sciences, Chiba (Japan)] [Advanced Radiation Biology Research Program, Research Center for Charged Particle Therapy, National Institute of Radiological Sciences, Chiba (Japan); Yasuda, Takeshi [Department of Radiation Emergency Medicine, Research Center for Radiation Emergency Medicine, National Institute of Radiological Sciences, Chiba (Japan)] [Department of Radiation Emergency Medicine, Research Center for Radiation Emergency Medicine, National Institute of Radiological Sciences, Chiba (Japan); Asada, Masahiro; Motomura, Kaori; Suzuki, Masashi [Signaling Molecules Research Laboratory, Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki (Japan)] [Signaling Molecules Research Laboratory, Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki (Japan); Zakrzewska, Malgorzata [Faculty of Biotechnology, University of Wroclaw (Poland)] [Faculty of Biotechnology, University of Wroclaw (Poland); Imamura, Toru [Signaling Molecules Research Laboratory, Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki (Japan)] [Signaling Molecules Research Laboratory, Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki (Japan); Imai, Takashi [Advanced Radiation Biology Research Program, Research Center for Charged Particle Therapy, National Institute of Radiological Sciences, Chiba (Japan)] [Advanced Radiation Biology Research Program, Research Center for Charged Particle Therapy, National Institute of Radiological Sciences, Chiba (Japan)

2013-02-01T23:59:59.000Z

144

Reduced Toxicity With Intensity Modulated Radiation Therapy (IMRT) for Desmoplastic Small Round Cell Tumor (DSRCT): An Update on the Whole Abdominopelvic Radiation Therapy (WAP-RT) Experience  

SciTech Connect

Purpose: Desmoplastic small round cell tumor (DSRCT) is a rare malignancy typically involving the peritoneum in young men. Whole abdominopelvic radiation therapy (WAP-RT) using conventional 2-dimensional (2D) radiation therapy (RT) is used to address local recurrence but has been limited by toxicity. Our objectives were to assess the benefit of intensity modulated radiation therapy (IMRT) on toxicity and to update the largest series on radiation for DSRCT. Methods and Materials: The records of 31 patients with DSRCT treated with WAP-RT (22 with 2D-RT and 9 with IMRT) between 1992 and 2011 were retrospectively reviewed. All received multi-agent chemotherapy and maximal surgical debulking followed by 30 Gy of WAP-RT. A further focal boost of 12 to 24 Gy was used in 12 cases. Boost RT and autologous stem cell transplantation were nearly exclusive to patients treated with 2D-RT. Toxicities were assessed with the Common Terminology Criteria for Adverse Events. Dosimetric analysis compared IMRT and simulated 2D-RT dose distributions. Results: Of 31 patients, 30 completed WAP-RT, with a median follow-up after RT of 19 months. Acute toxicity was reduced with IMRT versus 2D-RT: P=.04 for gastrointestinal toxicity of grade 2 or higher (33% vs 77%); P=.02 for grade 4 hematologic toxicity (33% vs 86%); P=.01 for rates of granulocyte colony-stimulating factor; and P=.04 for rates of platelet transfusion. Post treatment red blood cell and platelet transfusion rates were also reduced (P=.01). IMRT improved target homogeneity ([D05-D95]/D05 of 21% vs 46%) and resulted in a 21% mean bone dose reduction. Small bowel obstruction was the most common late toxicity (23% overall). Updated 3-year overall survival and progression-free survival rates were 50% and 24%, respectively. Overall survival was associated with distant metastasis at diagnosis on multivariate analysis. Most failures remained intraperitoneal (88%). Conclusions: IMRT for consolidative WAP-RT in DSRCT improves hematologic toxicity in particular. Although the long-term efficacy of current treatment options remains disappointing, the improved therapeutic index of IMRT may aid in generalizing its use and allowing the addition of novel approaches such as intraperitoneal immunotherapy.

Desai, Neil B. [Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States)] [Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Stein, Nicholas F. [Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, New York (United States)] [Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); LaQuaglia, Michael P. [Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York (United States)] [Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Alektiar, Kaled M. [Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States)] [Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Kushner, Brian H.; Modak, Shakeel; Magnan, Heather M. [Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York (United States)] [Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Goodman, Karyn [Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States)] [Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Wolden, Suzanne L., E-mail: woldens@mskcc.org [Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States)

2013-01-01T23:59:59.000Z

145

THE BIOLOGICAL EFFECTS OF IONIZING RADIATION: EPIDEMIOLOGICAL SURVEYS AND LABORATORY ANIMAL EXPERIMENTS. IMPLICATIONS FOR RISK EVALUATION AND DECISION PROCESSES  

E-Print Network (OSTI)

Atomic Bomb survivors 1950-1974. Mortality Experience of L i f e Span Study Reportatomic bomb survivor studies). Furthermore, the 1980 BEIR-III Report [

Fabrikant, J.I.

2010-01-01T23:59:59.000Z

146

Can sick buildings be assessed by testing human performance in field experiments  

Science Conference Proceedings (OSTI)

The present paper is devoted to the Sick Building Syndrome and describes an experiment comparing a diagnosed sick' with a healthy' Swedish preschool. The indoor air quality of both buildings were nearly the same and the concentrations of total separated volatile organic compounds were low according to suggested guidelines for indoor air in nonindustrial buildings. Forty-eight previously unexposed subjects were exposed to each of the two buildings for one day, and the effect of the exposure was assessed with a battery of diverse psychological test. Despite a favorable experimental situation of utilizing a building with a record of producing the Syndrome, the results of psychological tests of mental and motor performance, and therefore the answer to the question raised by the title above, were in the negative. This failure raises questions both regarding the choice of subjects and experimental methods including the selection of tests, the duration of exposure, and the environmental setting. Several combinations of experimental method and subjects which must be considered in future research on indoor pollution are discussed.

Berglund, B. (Univ. of Stockholm (Sweden)); Berglund, U. (Royal Inst. of Tech., Stockholm (Sweden)); Engen, T. (Brown Univ., Providence, RI (United States))

1992-01-01T23:59:59.000Z

147

POLARIZATION OF THE COSMIC BACKGROUND RADIATION  

E-Print Network (OSTI)

Galactic Synchrotron Radiation at 33 GHz NOIiWNPQaa s x s sthe Cosmic Background Radiation Philip Michael Lubin Spacethe Cosmic Background Radiation. The ground-based experiment

Lubin, Philip Lubin

2010-01-01T23:59:59.000Z

148

Effects of Adenovirus-Mediated Delivery of the Human Hepatocyte Growth Factor Gene in Experimental Radiation-Induced Heart Disease  

SciTech Connect

Purpose: Irradiation to the heart may lead to late cardiovascular complications. The purpose of this study was to investigate whether adenovirus-mediated delivery of the human hepatocyte growth factor gene could reduce post-irradiation damage of the rat heart and improve heart function. Methods and Materials: Twenty rats received single-dose irradiation of 20 Gy gamma ray locally to the heart and were randomized into two groups. Two weeks after irradiation, these two groups of rats received Ad-HGF or mock adenovirus vector intramyocardial injection, respectively. Another 10 rats served as sham-irradiated controls. At post-irradiation Day 120, myocardial perfusion was tested by myocardial contrast echocardiography with contrast agent injected intravenously. At post-irradiation Day 180, cardiac function was assessed using the Langendorff technique with an isolated working heart model, after which heart samples were collected for histological evaluation. Results: Myocardial blood flow was significantly improved in HGF-treated animals as measured by myocardial contrast echocardiography at post-irradiation Day 120 . At post-irradiation Day 180, cardiac function was significantly improved in the HGF group compared with mock vector group, as measured by left ventricular peak systolic pressure (58.80 +- 9.01 vs. 41.94 +- 6.65 mm Hg, p < 0.05), the maximum dP/dt (5634 +- 1303 vs. 1667 +- 304 mm Hg/s, p < 0.01), and the minimum dP/dt (3477 +- 1084 vs. 1566 +- 499 mm Hg/s, p < 0.05). Picrosirius red staining analysis also revealed a significant reduction of fibrosis in the HGF group. Conclusion: Based on the study findings, hepatocyte growth factor gene transfer can attenuate radiation-induced cardiac injury and can preserve cardiac function.

Hu Shunying; Chen Yundai [Department of Cardiology, Chinese PLA General Hospital, Beijing (China); Li Libing [Department of Cardiovascular Surgery, Chinese PLA General Hospital, Beijing (China); Chen Jinlong; Wu Bin [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing (China); Zhou, Xiao; Zhi Guang [Department of Cardiology, Chinese PLA General Hospital, Beijing (China); Li Qingfang; Wang Rongliang; Duan Haifeng; Guo Zikuan; Yang Yuefeng; Xiao Fengjun [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing (China); Wang Hua, E-mail: wanghua@nic.bmi.ac.c [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing (China); Wang Lisheng [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing (China)

2009-12-01T23:59:59.000Z

149

Regulation Of Nf=kb And Mnsod In Low Dose Radiation Induced Adaptive Protection Of Mouse And Human Skin Cells  

Science Conference Proceedings (OSTI)

A sampling of publications resulting from this grant is provided. One is on the subject of NF-κB-Mediated HER2 Overexpression in Radiation-Adaptive Resistance. Another is on NF-κB-mediated adaptive resistance to ionizing radiation.

Jian Li

2012-11-07T23:59:59.000Z

150

EXPERIENCE MONITORING FOR LOW LEVEL NEUTRON RADIATION AT THE H-CANYON AT THE SAVANNAH RIVER SITE  

Science Conference Proceedings (OSTI)

Department of Energy contractors are required to monitor external occupational radiation exposure of an individual likely to receive an effective dose equivalent to the whole body of 0.1 rem (0.001sievert) or more in a year. For a working year of 2000 hours, this translates to a dose rate of 0.05 mrem/hr (0.5 {micro}Sv/hr). This can be a challenging requirement for neutron exposure because traditional surveys with shielded BF{sub 3} proportional counters are difficult to conduct, particularly at low dose rates. A modified survey method was used at the Savannah River Site to find low dose rates in excess of 0.05 mrem/hr. An unshielded He{sup 3} detector was used to find elevated gross slow neutron counts. Areas with high count rates on the unshielded He{sup 3} detector were further investigated with shielded BF{sub 3} proportional counters and thermoluminescent neutron dosimeters were placed in the area of interest. An office area was investigated with this method. The data initially suggested that whole body neutron dose rates to office workers could be occurring at levels significantly higher than 0.1 rem (0.001sievert). The final evaluation, however, showed that the office workers were exposed to less than 0.1 rem/yr (0.001sievert/yr) of neutron radiation.

HOGUE, MARK

2005-10-07T23:59:59.000Z

151

A Personal Experience Reducing Radiation Exposures: Protecting Family in Kiev during the First Two Weeks after Chernobyl  

SciTech Connect

The Chernobyl nuclear reactor accident occurred in 1986. The plume from the explosions and fires was highly radioactive and resulted in very high exposure levels in the surrounding regions. This paper describes how the people in Kiev, Ukraine, a city 90 miles (120 km) south of Chernobyl, and in particular one individual in that city, Professor Vitaly Eremenko, became aware of the threat before the official announcement and the steps he took to mitigate potential impacts to his immediate family. The combination of being informed and using available resources led to greatly reduced consequences for his family and, in particular, his newborn granddaughter. He notes how quickly word of some aspects of the hazard spread in the city and how other aspects appear to not have been understood. Although these events are being recalled as the 20th anniversary of the terrible event approaches, the lessons are still pertinent today. Threats of possible terrorist use of radiation dispersal devices makes knowledge of effective individual actions for self-protection from radiation exposures a topic of current interest.

Eremenko, Vitaly A.; Droppo, James G.

2006-08-01T23:59:59.000Z

152

Low dose radiation hypersensitivity and clustered DNA damages in human fibroblasts exposed to low dose and dose rate protons or 137CS y-rays  

SciTech Connect

Effective radioprotection for human space travelers hinges upon understanding the individual properties of charged particles. A significant fraction of particle radiation astronauts will encounter in space exploratory missions will come from high energy protons in galactic cosmic radiation (GCR) and/or possible exposures to lower energy proton flux from solar particle events (SPEs). These potential exposures present major concerns for NASA and others, in planning and executing long term space exploratory missions. We recently reported cell survival and transformation (acquisition of anchorage-independent growth in soft agar) frequencies in apparently normal NFF-28 primary human fibroblasts exposed to 0-30 cGy of 50MeV, 100MeV (SPE-like), or 1000 MeV (GCR-like) monoenergetic protons. These were modeled after 1989 SPE energies at an SPE-like low dose-rate (LDR) of 1.65 cGy/min or high dose rate (HDR) of 33.3 cGy/min delivered at the NASA Space Radiation Laboratory (NSRL) at BNL.

Bennett P. V.; Bennett, P.V.; Keszenman, D.J.; Johnson, A.M.; Sutherland, B.M.; Wilson, P.F.

2013-05-14T23:59:59.000Z

153

Genetic susceptibility to low-dose ionizing radiation in the mouse mammary glandas a means of understanding human risk for breast cancer  

NLE Websites -- All DOE Office Websites (Extended Search)

susceptibility to low-dose ionizing radiation in the mouse mammary gland susceptibility to low-dose ionizing radiation in the mouse mammary gland as a means of understanding human risk for breast cancer Antoine M. Snijders 1 , Francesco Marchetti 1 , Ju Han 1 , Sandhya Bhatnagar 1 , Nadire Duru 1 , Zhi Hu 1 , Jian-Hua Mao 1 , Mina Bissell 1 , Joe Gray 1,2 , Gary H. Karpen 1 , Priscilla K. Cooper 1 and Andrew J. Wyrobek 1 1 Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 2 Current affiliation: Biomedical Engineering, Oregon Health Science Univ, Portland, OR Goal: Our goal is to develop an in vivo mechanistic model of genetic variation in the low-dose damage responses of mammary glands using inbred mice known to vary in their sensitivity to low-dose induced mammary gland cancer, and to develop molecular predictors for susceptibility or resistance to low-dose induced breast cancer.

154

Comparison of Unmonochromatized Synchrotron Radiation and Conventional X-rays in the Imaging of Mammographic Phantom and Human Breast Specimens: A Preliminary Result  

E-Print Network (OSTI)

A simple imaging setup based on the principle of coherence-based contrast X-ray imaging with unmonochromatized synchrotron radiation was used for studying mammographic phantom and human breast specimens. The use of unmonochromatized synchrotron radiation simplifies the instrumentation, decreases the cost and makes the procedure simpler and potentially more suitable for clinical applications. The imaging systems consisted of changeable silicon wafer attenuators, a tungsten slit system, a CdWO4 scintillator screen, a CCD (Charge Coupled Device) camera coupled to optical magnification lenses, and a personal computer. In preliminary studies, a spatial resolution test pattern and glass capillary filled with air bubbles were imaged to evaluate the resOolution characteristics and coherence-based contrast enhancement. Both the spatial resolution and image quality of the proposed system

Haijo Jung; Hee-joung Kim; Eun-kyung Kim; Jin-o Hong; Jung Ho Je; Yeukuang Hwu; Wen-li Tsai; Giorgio Magaritondo; Hyung-sik Yoo

2004-01-01T23:59:59.000Z

155

Fallout: The experiences of a medical team in the care of a Marshallese population accidently exposed to fallout radiation  

SciTech Connect

This report presents an historical account of the experiences of the Brookhaven Medical Team in the examination and treatment of the Marshallese people following their accidental exposure to radioactive fallout in 1954. This is the first time that a population has been heavily exposed to radioactive fallout, and even though this was a tragic mishap, the medical findings have provided valuable information for other accidents involving fallout such as the recent reactor accident at Chernobyl. Noteworthy has been the unexpected importance of radioactive iodine in the fallout in producing thyroid abnormalities.

Conard, R.A.

1992-09-01T23:59:59.000Z

156

Fallout: The experiences of a medical team in the care of a Marshallese population accidentally exposed to fallout radiation  

SciTech Connect

This report presents an historical account of the experiences of the Brookhaven Medical team in the examination and treatment of the Marshallese people following their accidental exposure to radioactive fallout in 1954. This is the first time that a population has been heavily exposed to radioactive fallout, and even though this was a tragic mishap, the medical findings have provided valuable information for other accidents involving fallout such as the recent reactor accident at Chernobyl. Particularly important has been the unexpected importance of radioactive iodine in the fallout in producing thyroid abnormalities.

Conard, R.A.

1991-01-01T23:59:59.000Z

157

Fallout: The experiences of a medical team in the care of a Marshallese population accidentally exposed to fallout radiation  

SciTech Connect

This report presents an historical account of the experiences of the Brookhaven Medical team in the examination and treatment of the Marshallese people following their accidental exposure to radioactive fallout in 1954. This is the first time that a population has been heavily exposed to radioactive fallout, and even though this was a tragic mishap, the medical findings have provided valuable information for other accidents involving fallout such as the recent reactor accident at Chernobyl. Particularly important has been the unexpected importance of radioactive iodine in the fallout in producing thyroid abnormalities.

Conard, R.A.

1991-12-31T23:59:59.000Z

158

Introduction and Fundamentals: Course on Advances in Radiation  

E-Print Network (OSTI)

exposure to Ionizing Radiation - is it really necessary?"Sternglass, "Environmental Radiation and Human Health," op.on the Effects of Atomic Radiation Sources and Effects of

Thomas, Ralph H.

2010-01-01T23:59:59.000Z

159

Oral Histories: Radiation Biologist Marvin Goldman, Ph.D.  

NLE Websites -- All DOE Office Websites (Extended Search)

8 8 HUMAN RADIATION STUDIES: REMEMBERING THE EARLY YEARS Oral History of Radiation Biologist Marvin Goldman, Ph.D. Conducted December 22, 1994 United States Department of Energy Office of Human Radiation Experiments September 1995 CONTENTS Foreword Short Biography Educational Background and Early Involvement in Radiation Research Brookhaven Acquaintances and Early Hospital Research (Circa 1952) Vulnerable Populations and Acceptable Risks Research at the University of Rochester (1952-57) Relationship with Newell Stannard and Stafford Warren (1952-57) Participation in "Project Sunshine" and Move to the University of California, Davis (Mid '50s to '58) Participation in Beagle Studies at the University of California at Davis (1958 to '60s) Budget Concerns and Goldman's Other Radiation Research Projects (1965 to Late '60s)

160

Cell Type-dependent Gene Transcription Profile in Three Dimensional Human Skin Tissue Model Exposed to Low Doses of Ionizing Radiation: Implications for Medical Exposures  

SciTech Connect

The concern over possible health risks from exposures to low doses of ionizing radiation has been driven largely by the increase in medical exposures, the routine implementation of X-ray backscatter devices for airport security screening, and, most recently, the nuclear incident in Japan. Due to a paucity of direct epidemiological data at very low doses, cancer risk must be estimated from high dose exposure scenarios. However, there is increasing evidence that low and high dose exposures result in different signaling events and may have different mechanisms of cancer induction. We have examined the radiation induced temporal response of an in vitro three dimensional (3D) human skin tissue model using microarray-based transcriptional profiling. Our data shows that exposure to 100 mGy of X-rays is sufficient to affect gene transcription. Cell type specific analysis showed significant changes in gene expression with the levels of > 1400 genes altered in the dermis and > 400 genes regulated in the epidermis. The two cell types rarely exhibited overlapping responses at the mRNA level. Quantitative reverse transcription polymerase chain reaction (qRT-PCR) measurements validated the microarray data in both regulation direction and value. Key pathways identified relate to cell cycle regulation, immune responses, hypoxia, reactive oxygen signaling, and DNA damage repair. We discuss in particular the role of proliferation and emphasizing how the disregulation of cellular signaling in normal tissue may impact progression towards radiation induced secondary diseases.

Freiin von Neubeck, Claere H.; Shankaran, Harish; Karin, Norman J.; Kauer, Paula M.; Chrisler, William B.; Wang, Xihai; Robinson, Robert J.; Waters, Katrina M.; Tilton, Susan C.; Sowa, Marianne B.

2012-04-17T23:59:59.000Z

Note: This page contains sample records for the topic "human radiation experiments" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
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161

Radiation Safety Manual Dec 2012 Page 1 RADIATION SAFETY  

E-Print Network (OSTI)

. Management Commitment B. Training C. Monitoring of Individual Radiation Exposures D. Program Reviews 1 of Radiation A. Research Applications 1. Non-Human User 2. Animal Use 3. Human Use B. Clinical Applications C Materials Chapter VI: Occupational Exposure to Radiation and Personnel Monitoring and Bioassay Program #12;A

Grishok, Alla

162

Radiation Response of Nano-scale Gold Foams  

Science Conference Proceedings (OSTI)

Our recent experiments and computer simulations focus on the radiation and mechanical response of nanoporous gold (NPG). Radiation tolerance was...

163

Effect of Increasing Experience on Dosimetric and Clinical Outcomes in the Management of Malignant Pleural Mesothelioma With Intensity-Modulated Radiation Therapy  

SciTech Connect

Purpose: To assess the impact of increasing experience with intensity-modulated radiation therapy (IMRT) after extrapleural pneumonectomy (EPP) for malignant pleural mesothelioma (MPM). Methods and Materials: The records of all patients who received IMRT following EPP at Duke University Medical Center between 2005 and 2010 were reviewed. Target volumes included the preoperative extent of the pleural space, chest wall incisions, involved nodal stations, and a boost to close/positive surgical margins if applicable. Patients were typically treated with 9-11 beams with gantry angles, collimator rotations, and beam apertures manually fixed to avoid the contalateral lung and to optimize target coverage. Toxicity was graded retrospectively using National Cancer Institute common toxicity criteria version 4.0. Target coverage and contralateral lung irradiation were evaluated over time by using linear regression. Local control, disease-free survival, and overall survival rates were estimated using the Kaplan-Meier method. Results: Thirty patients received IMRT following EPP; 21 patients also received systemic chemotherapy. Median follow-up was 15 months. The median dose prescribed to the entire ipsilateral hemithorax was 45 Gy (range, 40-50.4 Gy) with a boost of 8-25 Gy in 9 patients. Median survival was 23.2 months. Two-year local control, disease-free survival, and overall survival rates were 47%, 34%, and 50%, respectively. Increasing experience planning MPM cases was associated with improved coverage of planning target volumes (P=.04). Similarly, mean lung dose (P<.01) and lung V5 (volume receiving 5 Gy or more; P<.01) values decreased with increasing experience. Lung toxicity developed after IMRT in 4 (13%) patients at a median of 2.2 months after RT (three grade 3-4 and one grade 5). Lung toxicity developed in 4 of the initial 15 patients vs none of the last 15 patients treated. Conclusions: With increasing experience, target volume coverage improved and dose to the contralateral lung decreased. Rates of pulmonary toxicity were relatively low. However, both local and distant control rates remained suboptimal.

Patel, Pretesh R., E-mail: patel073@mc.duke.edu [Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina (United States); Yoo, Sua [Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina (United States); Broadwater, Gloria [Cancer Center Biostatistics, Duke University Medical Center, Durham, North Carolina (United States); Marks, Lawrence B. [Department of Radiation Oncology, University of North Carolina, Chapel Hill, North Carolina (United States); Miles, Edward F. [Naval Medical Center, Portsmouth, Virginia (United States); D'Amico, Thomas A.; Harpole, David [Department of Surgery, Division of Thoracic Surgery, Duke University Medical Center, Durham, North Carolina (United States); Kelsey, Chris R. [Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina (United States)

2012-05-01T23:59:59.000Z

164

USE OF COHERENT TRANSITION RADIATION TO SET UP THE APS RF THERMIONIC GUN TO PRODUCE HIGH-BRIGHTNESS BEAMS FOR SASE FEL EXPERIMENTS ?  

E-Print Network (OSTI)

We describe use of the Advanced Photon Source (APS) rf thermionic gun [1], alpha-magnet beamline, and linac [2] to produce a stable high-brightness beam in excess of 100 amperes peak current with normalized emittance of 10 ? mm-mrad. To obtain peak currents greater than 100 amperes, the rf gun system must be tuned to produce a FWHM bunch length on the order of 350 fs. Bunch lengths this short are measured using coherent transition radiation (CTR) produced when the rf gun beam, accelerated to 40 MeV, strikes a metal foil. The CTR is detected using a Golay detector attached to one arm of a Michelson interferometer. The alpha-magnet current and gun rf phase are adjusted so as to maximize the CTR signal at the Golay detector, which corresponds to the minimum bunch length. The interferometer is used to measure the autocorrelation of the CTR. The minimum phase approximation [3] is used to derive the bunch profile from the autocorrelation. The high-brightness beam is accelerated to 217 MeV and used to produce self-amplified spontaneous emission (SASE) in five APS undulators installed in the Low- Energy Undulator Test Line (LEUTL) experiment hall [4]. Initial optical measurements showed a gain length of 1.3 m at 530 nm. 1

unknown authors

2000-01-01T23:59:59.000Z

165

Measuring Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Measurement Activity SI Units and Prefixes Conversions Safety Around Radiation Sources Types of Radiation Exposure Managing Radiation Emergencies Procedure Demonstration...

166

Radiation Inspection System Lab (RISL) | ORNL  

NLE Websites -- All DOE Office Websites (Extended Search)

Radiation Inspection System Lab May 30, 2013 This team has the background and experience to test and optimize radiation detection systems from handheld background survey meters to...

167

Lack of effects of atomic bomb radiation on genetic instability of tandem-repetitive elements in human germ cells  

Science Conference Proceedings (OSTI)

In a pilot study to detect the potential effects of atomic bomb radiation on germ-line instability, we screened 64 children from 50 exposed families and 60 from 50 control families for mutations at six minisatellite loci by using Southern blot analysis with Pc-1, {lambda}TM-18, ChdTC-15, p{lambda}g3, {lambda}MS-1, and CEB-1 probes. In the exposed families, one or both parents received a radiation dose >0.01 Sv. Among the 64 children, only one child had parents who were both exposed. Thus, of a total of 128 gametes that produced the 64 children, 65 gametes were derived from exposed parents and 63 were from unexposed parents, the latter being included in a group of 183 unexposed gametes used for calculating mutation rates. The average parental gonadal dose for the 65 gametes was 1.9 Sv. We detected a total of 28 mutations at the p{lambda}g3, {lambda}MS-1, and CEB-1 loci, but no mutations at the Pc-1, {lambda}TM-18, and ChdTC-15 loci. We detected 6 mutations in 390 alleles of the 65 exposed gametes and 22 mutations in 1098 alleles of the 183 gametes from the unexposed parents. The mean mutation rate per locus per gamete in these six minisatellite loci was 1.5% in the exposed parents and 2.0% in the unexposed parents. We observed no significant difference in mutation rates in the children of the exposed and the unexposed parents (P = .37, Fisher`s exact probability test). 38 refs., 1 fig., 5 tabs.

Kodaira, Mieko; Satoh, Chiyoko [Radiation Effects Research Foundation, Hiroshima (Japan); Hiyama, Keiko [Radiation Effects Research Foundation, Hiroshima (Japan)]|[Hiroshima Univ. School of Medicine (Japan)] [and others

1995-12-01T23:59:59.000Z

168

29th International Cosmic Ray Conference Pune (2005) 1, 301-302 Human Exploration of the Moon and Mars: Space Radiation Data,  

E-Print Network (OSTI)

and development of instrumentation to guide NASA in managing the radiation exposure of the crew during the manned to carefully manage the radiation exposure of the crew in real time because of the variability of the radiation occurs. This is especially true if it occurs during a lunar excursion. A substantial radiation exposure

Lin, Zi-wei

169

Low Dose Radiation Research Program: Genetic Factors Affecting  

NLE Websites -- All DOE Office Websites (Extended Search)

Genetic Factors Affecting Susceptibility to Low-Doses of Ionizing Genetic Factors Affecting Susceptibility to Low-Doses of Ionizing Radiation. Authors: William F. Morgan, Pat Concannon & John H.J. Petrini The goal of this program is to test the hypothesis that mice heterozygous for the NBS1 gene are genetically susceptible to low doses of ionizing radiation. Patients with Nijmegen Breakage Syndrome (NBS) are radiation sensitive, because of defects in cellular responses to radiation induced genetic damage. It is unclear whether humans heterozygous for the mutations associated with NBS are radiation sensitive and results from cell culture experiments give conflicting results. In collaboration with John Petrini at the Memorial Sloan Kettering Cancer Center in New York City we developed a mouse model of this disorder and are directly testing the hypothesis

170

Effects of atomic radiation  

SciTech Connect

This book focuses on the lifelong effects of atomic radiation exposure in language understandable by the concerned layperson or the specialist in another field. The base of knowledge used is the work of the Atomic Bomb Casualty Commission and its successor since 1975 the Radiation Effects Research Foundation. Within the range of Chronic effects on human health the book provides a thorough review, although effects of nonionizing radiation, effects on structures, effects on other living species, and acute effects are not discussed.

Schull, W.J.

1995-12-31T23:59:59.000Z

171

Radiation Budgets in the Western Tropical Pacific  

Science Conference Proceedings (OSTI)

The usefulness of the radiances measured by operational satellites in deriving radiation budgets is demonstrated by comparing the model calculations with the Earth Radiation Budget Experiment (ERBE) fluxes. The radiation budgets in the atmosphere ...

Mino-Dah Chou

1994-12-01T23:59:59.000Z

172

Spatial Variability of Outgoing Longwave Radiation  

Science Conference Proceedings (OSTI)

Data from the Earth Radiation Budget Experiment scanning radiometer aboard the NOAA-9 operational meteorological satellite are used to investigate the spatial variability of outgoing longwave radiation (OLR). Daily and monthly radiation maps at ...

G. Louis Smith; David Rutan

1994-07-01T23:59:59.000Z

173

Sandia Laboratories radiation facilities  

SciTech Connect

This brochure is designed as a basic source of information for prospective users of Sandia Laboratories Radiation Facilities. It contains a brief description of the various major radiation sources, a summary of their output characteristics, and additional information useful to experimenters. Radiation source development and source upgrading is an ongoing program, with new source configurations and modes of operation continually being devised to satisfy the ever-changing radiation requirements of the users. For most cases, the information here should allow a potential user to assess the applicability of a particular radiation facility to a proposed experiment and to permit some preirradiation calculations and planning.

Choate, L.M.; Schmidt, T.R.; Schuch, R.L.

1977-07-01T23:59:59.000Z

174

The Effects of Radiation on Development of Prostate Cancer and Prostatic  

NLE Websites -- All DOE Office Websites (Extended Search)

Effects of Radiation on Development of Prostate Cancer and Prostatic Effects of Radiation on Development of Prostate Cancer and Prostatic Hyperplasia in Canine Model Gayle Woloschak Northwestern University Abstract Purpose/Objective(s): There have been few studies analyzing radiation-induced prostate cancer in humans or animals. Our research attempts to fill this void by determining the effects of cobalt-60 gamma radiation on the incidence of prostate cancer and prostatic hyperplasia in a large cohort of beagle dogs. Material/Methods: The subjects for the experiment were beagle dogs, which were chosen due to physiologic and anatomic similarities to humans (Thompson, 1989). We retrospectively analyzed data from historic irradiation experiments conducted at Argonne National Laboratory on 347 beagles. The cobalt-60 cohort consisted of 268 dogs, which received whole

175

Does an accelerated electron radiate Unruh radiation?  

E-Print Network (OSTI)

An accelerated particle sees the Minkowski vacuum as thermally excited, and the particle moves stochastically due to an interaction with the thermal bath. This interaction fluctuates the particle's transverse momenta like the Brownian motion in a heat bath. Because of this fluctuating motion, it has been discussed that the accelerated charged particle emits extra radiation (the Unruh radiation) in addition to the classical Larmor radiation, and experiments are under planning to detect such radiation by using ultrahigh intensity lasers constructed in near future. There are, however, counterarguments that the radiation is canceled by an interference effect between the vacuum fluctuation and the fluctuating motion. In fact, in the case of an internal detector where the Heisenberg equation of motion can be solved exactly, there is no additional radiation after the thermalization is completed. In this paper, we revisit the issue in the case of an accelerated charged particle in the scalar QED. We first prove the e...

Iso, Satoshi; Zhang, Sen

2010-01-01T23:59:59.000Z

176

About Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Radiation What is radiation? Radiation is a form of energy that is a part of our everyday lives. All of us receive a "dose" of radiation each day. Most of the dose comes from...

177

Estimation and Model Validation of Surface Solar Radiation and Cloud Radiative Forcing Using TOGA COARE Measurements  

Science Conference Proceedings (OSTI)

The Tropical Ocean and Global Atmosphere Coupled OceanAtmosphere Response Experiment (TOGA COARE) radiation measurements in the western Pacific warm pool are used to estimate surface solar radiation budgets and to validate radiation model ...

Ming-Dah Chou; Wenzhong Zhao

1997-04-01T23:59:59.000Z

178

Radiation: Radiation Control (Indiana)  

Energy.gov (U.S. Department of Energy (DOE))

It is the policy of the state to encourage the constructive uses of radiation and to control its harmful effects. This section contains regulations pertaining to the manufacture, use,...

179

Acute radiation syndrones and their management  

Science Conference Proceedings (OSTI)

Radiation syndromes produced by large doses of ionizing radiation are divided into three general groups depending on dose of radiation and time after exposure. The CNS syndrome requires many thousands of rad, appears in minutes to hours, and kills within hours to days. The GIS appears after doses of a few hundred to 2000 rad. It is characterized by nausea, vomiting, diarrhea, and disturbances of water and electrolyte metabolism. It has a high mortality in the first week after exposure. Survivors will then experience the HS as a result of marrow aplasia. Depending on dose, survival is possible with antibiotic and transfusion therapy. The relationship of granulocyte depression to mortality in dogs and human beings is illustrated. The role of depth dose pattern of mortality of radiation exposure is described and used as an indication of why air exposure doses may be misleading. The therapy of radiation injury is described based on antibiotics, transfusion therapy, and use of molecular regulators. The limited role of matched allogenic bone marrow transplants is discussed. 52 refs., 13 figs.

Cronkite, E.P.

1988-01-01T23:59:59.000Z

180

Protection Against Ionizing Radiation in Extreme Radiation ...  

Science Conference Proceedings (OSTI)

Protection Against Ionizing Radiation in Extreme Radiation-resistant Microorganisms. ... Elucidated radiation protection by intracellular halides. ...

2013-05-01T23:59:59.000Z

Note: This page contains sample records for the topic "human radiation experiments" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


181

IN-PILE RADIATION CORROSION EXPERIMENTS WITH ZIRCONIUM, TITANIUM, AND STEEL ALLOYS IN 0.17 m UO$sub 2$SO$sub 4$ SOLUTIONS AT 280 C  

SciTech Connect

In-pile loop experiments L-2-15 and L-4-16 were designed to test the radiation corrosion of Zircaloy-2 and other possible reactor construction materials in UO/sub 2/SO/sub 4/ solutions. The solutions employed were 0.17 m UO/ sub 2/SO/sub 4/, 0.015 m CuSO/sub 4/, and 0.03 m H/sub 2/SO/sub 4/ in H/sub 2/O for experiment L-2-15, and 0.17 m UO/sub 2/SO/sub 4/, 0.015 m CuSO/sub 4/, and 0.025 m H/sub 2/SO/sub 4/ in H/sub 2/O for experiment L-4-16. The mainstream temperature in the experiments ranged from 278 to 280 deg C. Construction material for the loops was type 347 stainless steel. Specimens of types 347 and 309SCb stainless steels titanium-55A and -110AT, platinum, Zircaloy-2, crystalbar zirconium, and a variety of other zirconium alloys were tested. The power density at core specimens ranged from 19.8 to 4.6 w/ml in L-2-15 and from 5.7 to 1.3 w/ml in L-4-16. For loop L-2-15, the total time of hightemperature operation with UO/sub 2/SO/sub 4/ was 792 hr, during in-pile exposure, and the reactor energy was 1632 Mwh; for loop L-4-16, 1032 hr and 2325 Mwh. During both experiments most of the reactor energy was accumulated at 3-Mw power level. In general, stainless steel corrosion results from these experiments were comparable to those observed in other in-pile loop experiments. Corrosion was confined primarily to the core areas and was power-density dependent. Some variations in attack, both positive and negative, with velocity of solution flow past specimens have been observed in other experiments, but there was no apparent effect of varying velocities in the range 10 to 40 fps on either the core-channel or in- line channel specimens in the present experiments. The coreannulus steel specimens in L-2-15 corroded at rates very much greater than those in the channel. This difference may have resulted, in part, from the differences in velocities, however, it may have also been a result of galvanic actton between the steel annulus specimens and adjacent platinum specimens. In previous 250 deg C experiments the occurrence of a change in the stainless steel corrosion rate was correlated with a decrease in acidity and/or increase in the nickel concentration. The results for the oxygen consumption rates on steel during radiation exposure in the present experiments varied with radiation time in a manner qualitatively similar to that observed at the lower temperature. However, the concentration of excess acid in the present experiments probably remained fairly constant throughout the radiation exposures, and correlations similar to those obtained at the lower temperature could not be established. The acid concentration in the 280 deg C experiments was greater than the concentrations prevailing when corrosion rate changes occurred in the 250 deg C experiments. The difference in acid tolerance is probably a result of the increased temperature, since a similar beneficial effect of temperature occurs out-ofpile No overall correlation has been established for the various factors found to have influenced steel corrosion in previous experiments. Results of the present experiments provide additional evidence in support of previous findings but do not further their interpretation. Zircaloy-2 corrosion results from both loops have been discussed and correlated elsewhere in terms of the 280 deg C relationship between the corrosion rate R (mils per year, mpy), power density P (w/ml), and uranium sorption factor alpha : 1/R = 2.23/P alpha + 1/40. The data from these experiments obey this relationship. (This is only a portion of the Author abstract.)

Jenks, G.H.; Baker, J.E.

1963-07-10T23:59:59.000Z

182

Five-year Results of Whole Breast Intensity Modulated Radiation Therapy for the Treatment of Early Stage Breast Cancer: The Fox Chase Cancer Center Experience  

Science Conference Proceedings (OSTI)

Purpose: To report the 5-year outcomes using whole-breast intensity-modulated radiation therapy (IMRT) for the treatment of early-stage-breast cancer at the Fox Chase Cancer Center. Methods and Materials: A total of 946 women with early-stage breast cancer (stage 0, I, or II) were treated with IMRT after surgery with or without systemic therapy from 2003-2010. Whole-breast radiation was delivered via an IMRT technique with a median whole-breast radiation dose of 46 Gy and median tumor bed boost of 14 Gy. Endpoints included local-regional recurrence, cosmesis, and late complications. Results: With a median follow-up of 31 months (range, 1-97 months), there were 12 ipsilateral breast tumor recurrences (IBTR) and one locoregional recurrence. The 5-year actuarial IBTR and locoregional recurrence rates were 2.0% and 2.4%. Physician-reported cosmestic outcomes were available for 645 patients: 63% were considered 'excellent', 33% 'good', and =}16 Gy, breast size >900 cc, or boost volumes >34 cc were significantly associated with a 'fair/poor' cosmetic outcome. Fibrosis, edema, erythema, and telangectasia were also associated with 'fair/poor' physician-reported cosmesis; erythema and telangectasia remained significant on multivariate analysis. Patient-reported cosmesis was available for 548 patients, and 33%, 50%, and 17% of patients reported 'excellent', 'good', and 'fair/poor' cosmesis, respectively. The use of a boost and increased boost volume: breast volume ratio were significantly associated with 'fair/poor' outcomes. No parameter for patient-reported cosmesis was significant on multivariate analysis. The chances of experiencing a treatment related effect was significantly associated with a boost dose {>=}16 Gy, receipt of chemotherapy and endocrine therapy, large breast size, and electron boost energy. Conclusions: Whole-breast IMRT is associated with very low rates of local recurrence at 5 years, 83%-98% 'good/excellent' cosmetic outcomes, and minimal chronic toxicity, including late fibrosis.

Keller, Lanea M.M., E-mail: Lanea.Keller@fccc.edu [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States); Sopka, Dennis M. [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States)] [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States); Li Tianyu [Department of Biostatistics, Fox Chase Cancer Center, Philadelphia, PA (United States)] [Department of Biostatistics, Fox Chase Cancer Center, Philadelphia, PA (United States); Klayton, Tracy; Li Jinsheng; Anderson, Penny R. [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States)] [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States); Bleicher, Richard J.; Sigurdson, Elin R. [Department of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States)] [Department of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States); Freedman, Gary M. [Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA (United States)] [Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA (United States)

2012-11-15T23:59:59.000Z

183

RADIATION MONITORING  

E-Print Network (OSTI)

of Monitoring for Radiation Protection of Workers" in ICRPNo. 9, in "Advances in Radiation Protection and Dosimetry inDosimetry f o r Stray Radiation Monitoring on the CERN S i t

Thomas, R.H.

2010-01-01T23:59:59.000Z

184

Radiation and viral DNA  

NLE Websites -- All DOE Office Websites (Extended Search)

Radiation and viral DNA Radiation and viral DNA Name: Loretta L Lamb Age: N/A Location: N/A Country: N/A Date: N/A Question: Can viral DNA be changed through exposure to radiation? If so, what type of radiation will do this? Can these irradiated viruses cause changes in the genome of any human cells they may infect? Can these (or any) viruses actually cause cancer, or do they merely act as triggering devices for cancer? Replies: In theory, any nucleic acid (viral or otherwise) can be changed by exposure to many kinds of radiation. Depending on the type of virus, these may then change the human cells that they infect. Although there are many different things that are being implicated in causing cancers, it looks like a fairly common model involves the sequential "knockout" of several human genes. Viruses may be one cause of such gene changes, radiation and other environmental causes may also contribute. Some of these changes may be inherited through families, so it becomes more likely that the environmental factors may happen to "hit" the right places in cells to cause cancers in these families. If you ask something more specific, perhaps I can focus my response a bit more

185

Use of Coherent Transition Radiation to Set Up the APS RF Thermionic Gun to Produce High-Brightness Beams for SASE FEL Experiments  

E-Print Network (OSTI)

We describe use of the Advanced Photon Source (APS) rf thermionic gun, alpha magnet beamline, and linac to produce a stable high-brightness beam in excess of 100 amperes peak current with normalized emittance of 10 pi mm-mrad. To obtain peak currents greater than 100 amperes, the rf gun system must be tuned to produce a FWHM bunch length on the order of 350 fs. Bunch lengths this short are measured using coherent transition radiation (CTR) produced when the rf gun beam, accelerated to 40 MeV, strikes a metal foil. The CTR is detected using a Golay detector attached to one arm of a Michelson interferometer. The alpha magnet current and gun rf phase are adjusted so as to maximize the CTR signal at the Golay detector, which corresponds to the minimum bunch length. The interferometer is used to measure the autocorrelation of the CTR radiation. The minimum phase approximation is used to derive the bunch profile from the autocorrelation. The high-brightness beam is accelerated to 217 MeV and used to produce SASE in...

Sereno, N S; Lumpkin, Alex H; Sereno, Nicholas; Borland, Michael; Lumpkin, Alex

2000-01-01T23:59:59.000Z

186

Low Dose Radiation Research Program: Multidimensional Analysis...  

NLE Websites -- All DOE Office Websites (Extended Search)

Multidimensional Analysis of Human Epithelial Cell Response to Low Dose Radiation Mary Helen Barcellos-Hoff Lawrence Berkeley National Laboratory Berkeley, CA. (Jointly funded by...

187

Low Dose Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Ancient Salt Beds Ancient Salt Beds Repository Science Renewable Energy The WIPP Underground may be ideal to study effects of Very Low Dose Rates on Biological Systems Low Background Radiation Experiment We're all bathing in it. It's in the food we eat, the water we drink, the soil we tread and even the air we breathe. It's background radiation, it's everywhere and we can't get away from it. But what would happen if you somehow "pulled the plug" on natural background radiation? Would organisms suffer or thrive if they grew up without their constant exposure to background radiation? That's what a consortium of scientists conducting an experiment at the Waste Isolation Pilot Plant aim to find out. Despite being an underground repository for transuranic radioactive waste,

188

Optical Radiation  

Science Conference Proceedings (OSTI)

*. Bookmark and Share. Optical Radiation Measurements. Fees for services are located directly below the technical contacts ...

2013-04-09T23:59:59.000Z

189

Ionizing Radiation  

Science Conference Proceedings (OSTI)

*. Bookmark and Share. Ionizing Radiation Measurements. Fees for services are located directly below the technical contacts ...

2013-04-09T23:59:59.000Z

190

The Geostationary Earth Radiation Budget Project  

Science Conference Proceedings (OSTI)

This paper reports on a new satellite sensor, the Geostationary Earth Radiation Budget (GERB) experiment. GERB is designed to make the first measurements of the Earth's radiation budget from geostationary orbit. Measurements at high absolute ...

J. E. Harries; J. E. Russell; J. A. Hanafin; H. Brindley; J. Futyan; J. Rufus; S. Kellock; G. Matthews; R. Wrigley; A. Last; J. Mueller; R. Mossavati; J. Ashmall; E. Sawyer; D. Parker; M. Caldwell; P. M. Allan; A. Smith; M. J. Bates; B. Coan; B. C. Stewart; D. R. Lepine; L. A. Cornwall; D. R. Corney; M. J. Ricketts; D. Drummond; D. Smart; R. Cutler; S. Dewitte; N. Clerbaux; L. Gonzalez; A. Ipe; C. Bertrand; A. Joukoff; D. Crommelynck; N. Nelms; D. T. Llewellyn-Jones; G. Butcher; G. L. Smith; Z. P. Szewczyk; P. E. Mlynczak; A. Slingo; R. P. Allan; M. A. Ringer

2005-07-01T23:59:59.000Z

191

Smith Purcell radiation from femtosecond electron bunches  

E-Print Network (OSTI)

We present theoretical and experimental results from a Smith-Purcell radiation experiment using the electron beam from a 17 GHz high gradient accelerator. Smith- Purcell radiation occurs when a charged particle travels ...

Korbly, Stephen E

2005-01-01T23:59:59.000Z

192

About Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Radiation Radiation What is radiation? Radiation is a form of energy that is a part of our everyday lives. All of us receive a "dose" of radiation each day. Most of the dose comes from naturally occurring radioactive materials such as uranium, thorium, radon, and certain forms of potassium and carbon. The air we breathe contains radon, the food we eat contains uranium and thorium from the soil, and our bodies contain radioactive forms of potassium and carbon. Cosmic radiation from the sun also contributes to our natural radiation dose. We also receive radiation doses from man-made sources such as X-rays, nuclear medical procedures, power plants, smoke detectors and older television sets. Some people, such as nuclear plant operators, flight crews, and nuclear medicine staff may also receive an occupational radiation dose.

193

Multi-Institutional Experience of Ductal Carcinoma In Situ in Black vs White Patients Treated With Breast-Conserving Surgery and Whole Breast Radiation Therapy  

SciTech Connect

Purpose: Given the paucity of data on racial disparities in ductal carcinoma in situ (DCIS), the data from a multi-institutional cohort of DCIS patients treated with breast-conserving surgery and whole breast radiation therapy (RT) were analyzed to determine whether racial disparities or differences exist. Methods and Materials: A total of 533 white and 76 black DCIS patients from 3 university-based cancer centers were uniformly treated with breast-conserving surgery and RT. All patient data were collected and analyzed as a function of race. Results: The median follow-up was 5.2 years. No significant racial differences were seen in tumor size, age at diagnosis, estrogen receptor status, necrosis, or grade (all P>.05). Of the treatment parameters, the RT dose delivered, boost, positive margin rates, frequency of hormone receptor status assessment, and receipt of hormonal therapy for the 2 cohorts did not significantly differ (all P>.05). The local relapse-free survival was similar at 5 years (96.1% and 98.1%, P=.399) and 10 years (92.8% vs 95.8%, P=.360), with no significant overall survival difference at 10 years (94.0% vs 88.9%, P=.290) between the white and black patients, respectively. On multivariate analysis, race was not an independent predictor of local relapse-free survival or overall survival when accounting for age, grade, and margin status. Conclusion: In our large cohort of DCIS patients uniformly treated at 3 institutions with breast conservation without any apparent differences in treatment delivery parameters, we demonstrated that the clinical and pathologic features and local survival outcomes did not differ as a function of race. Our results suggest that when black patients with DCIS are appropriately selected for breast conservation and receive adjuvant RT without racial disparities in the treatment parameters, differences in the outcomes as a function of race do not exist.

Nelson, Carl [Robert Wood Johnson Medical School, New Brunswick, New Jersey (United States)] [Robert Wood Johnson Medical School, New Brunswick, New Jersey (United States); Bai, Harrison [Yale University School of Medicine, New Haven, Connecticut (United States)] [Yale University School of Medicine, New Haven, Connecticut (United States); Neboori, Hanmanth [Drexel Medical College, Philadelphia, Pennsylvania (United States)] [Drexel Medical College, Philadelphia, Pennsylvania (United States); Takita, Cristiane [University of Miami, Miami, Florida (United States)] [University of Miami, Miami, Florida (United States); Motwani, Sabin [Robert Wood Johnson Medical School, New Brunswick, New Jersey (United States)] [Robert Wood Johnson Medical School, New Brunswick, New Jersey (United States); Wright, Jean L.; Hobeika, Georges [University of Miami, Miami, Florida (United States)] [University of Miami, Miami, Florida (United States); Haffty, Bruce G. [Robert Wood Johnson Medical School, New Brunswick, New Jersey (United States)] [Robert Wood Johnson Medical School, New Brunswick, New Jersey (United States); Jones, Tiffanie [Yale University School of Medicine, New Haven, Connecticut (United States)] [Yale University School of Medicine, New Haven, Connecticut (United States); Goyal, Sharad [Robert Wood Johnson Medical School, New Brunswick, New Jersey (United States)] [Robert Wood Johnson Medical School, New Brunswick, New Jersey (United States); Moran, Meena S., E-mail: meena.moran@yale.edu [Yale University School of Medicine, New Haven, Connecticut (United States)

2012-11-01T23:59:59.000Z

194

Low Dose Radiation Research Program: Rainer K. Sachs  

NLE Websites -- All DOE Office Websites (Extended Search)

Rainer K. Sachs Rainer K. Sachs University of California, Berkeley Funded Projects BIO-BASED RISK MODELING 03-20: Modeling the Interrelations Among Radiation-Induced Bystander Effects, Genomic Instability and Cancer Cytogenetic Tests of Radiobiological Models Relating Epidemiologically Measurable Risks to Low-Dose Risks Technical Abstracts 2006 Workshop The Bystander Effect in Normal Human 3-D Tissue: Experiments, Models, and Implications Brenner, D., Ponnaiya, B., Shuryak, I., Sachs, R., and Geard, D. Radiation Carcinogenesis Risk as Influenced by Intercellular Interaction Hahnfeldt, P., Hlatky, L., and Sachs, R.K. 2005 Workshop: Modelling Intercellular Interactions During Radiation Carcinogenesis Sachs, R.K., Chan, M., Hlatky, L., and Hahnfeldt, P. 2003 Workshop: Chromosome Spatial Clustering Uncovered Through Radiogenic Aberrations

195

Radiation Physics Portal  

Science Conference Proceedings (OSTI)

NIST Home > Radiation Physics Portal. Radiation Physics Portal. ... more. >> see all Radiation Physics programs and projects ... ...

2013-08-08T23:59:59.000Z

196

Low Dose Radiation Research Program: Low Dose Radiation Effects in  

NLE Websites -- All DOE Office Websites (Extended Search)

Radiation Effects in Differentiating Human Lens Cells Radiation Effects in Differentiating Human Lens Cells E.A. Blakely1, M.P. McNamara1, P.Y. Chang1, K.A. Bjornstad1, D. Sudar1, and A.C. Thompson2 1Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California; 2Advanced Light Source Division, Lawrence Berkeley National Laboratory, Berkeley, California. Introduction The human lens is one of the most radiosensitive organs of the body. Cataract, the opacification of the lens, is a late-appearing response to radiation damage. There are few data available on the late radiation effects of exposure in space flight to charged particle beams, the most prevalent of which are protons. Basic research in this area is needed to integrate the responses of both critical and other representative tissues

197

Radiation Cataract  

NLE Websites -- All DOE Office Websites (Extended Search)

radiation including patients undergoing diagnostic CT scans or radiotherapy, atomic bomb survivors, residents of radioactively contaminated buildings, victims of the...

198

Earth Radiation Budget: Results of Outgoing Longwave Radiation from Nimbus-7, NOAA-9, and ERBS Satellites  

Science Conference Proceedings (OSTI)

Eighteen months of wide field-of-view (WFOV) outgoing longwave radiation (OLR) measurements from the Earth Radiation Budget Experiment (ERBE) NOAA-9 and NOAA-10 spacecraft have been deconvolved to produce resolution-enhanced flux maps at the top ...

T. Dale Bess; G. Louis Smith

1993-05-01T23:59:59.000Z

199

Chronic Low Dose Radiation Effects on Radiation Sensitivity  

NLE Websites -- All DOE Office Websites (Extended Search)

Chronic Low Dose Radiation Effects on Radiation Sensitivity Chronic Low Dose Radiation Effects on Radiation Sensitivity and Chromosome Instability Induction in TK6 Cells Schwartz J.L. 1 , Jordan R. 1 , Slovic J. 1 , Moruzzi A. 1 , Kimmel R. 2 , and Liber, H.L. 3 1 University of Washington, Seattle, WA; 2 Fred Hutchinson Cancer Research Center, Seattle, WA; 3 Colorado State University, Fort Collins, Colorado There are a number of cell responses that can be detected after low dose radiation exposures including the adaptive response, low dose hypersensitivity, and induced genomic instability. The relationship between these different phenomena is unknown. In this study, we measured adaptive responses, low dose hypersensitivity, and induced genomic instability in a human B-lymphoblastoid cell model, TK6, where we could genetically modify radiation responses by either over-expression of BCL-2 or deletion of TP53. TK6

200

Measurement of Radiation Damage on Silica Aerogel \\v Cerenkov Radiator  

E-Print Network (OSTI)

We measured the radiation damage on silica aerogel \\v Cerenkov radiators originally developed for the $B$-factory experiment at KEK. Refractive index of the aerogel samples ranged from 1.012 to 1.028. The samples were irradiated up to 9.8~MRad of equivalent dose. Measurements of transmittance and refractive index were carried out and these samples were found to be radiation hard. Deteriorations in transparency and changes of refractive index were observed to be less than 1.3\\% and 0.001 at 90\\% confidence level, respectively. Prospects of using aerogels under high-radiation environment are discussed.

S. K. Sahu et al

1996-04-11T23:59:59.000Z

Note: This page contains sample records for the topic "human radiation experiments" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


201

Risk of Low Dose/Low Dose Rate Ionizing Radiation to Humans Symposium at the EMS 2009 Annual Meeting - September 2006  

Science Conference Proceedings (OSTI)

The low dose symposium thoughtfully addressed controversy of risk from low dose radiation exposure, hormesis and radon therapy. The stem cell symposium cogently considered the role of DNA damage and repair in hematopoietic stem cells underlying aging and malignancy and provocatively presented evidence that stem cells may have distinct morphologies and replicative properties, as well as special roles in cancer initiation. In the epigenetics symposium, studies illustrated the long range interaction of epigenetic mechanisms, the roles of CTCF and BORIS in region/specific regulation of epigenetic processes, the impact of DNA damage on epigenetic processes as well as links between epigenetic mechanisms and early nutrition and bystander effects.

Morgan, William F.; von Borstel, Robert C.; Brenner,; Redpath, J. Leslie; Erickson, Barbra E.; Brooks,

2009-11-12T23:59:59.000Z

202

Roadmap to the Project: Experiments List  

NLE Websites -- All DOE Office Websites (Extended Search)

into the environment. These releases were designed to characterize the dispersion of radiation. The purpose of the experiment was to enable scientists to determine the fraction...

203

Radiation Information  

NLE Websites -- All DOE Office Websites (Extended Search)

Radiation Information << Timeline >> Content on this page requires a newer version of Adobe Flash Player. Get Adobe Flash player July 31, 1942 The Army Corp of Engineers leases...

204

Experiment #8: Radiation Makes House Calls  

NLE Websites -- All DOE Office Websites (Extended Search)

materials in front of the Geiger counter. Record the reading in Table 8.1. Applying usage of the "Chart of Nuclides," recorded data in Table 8.1 and 8.2, fill in the question...

205

Radiation-Hard Quartz Cerenkov Calorimeters  

Science Conference Proceedings (OSTI)

New generation hadron colliders are going to reach unprecedented energies and radiation levels. Quartz has been identified as a radiation-hard material that can be used for Cerenkov calorimeters of the future experiments. We report from the radiation hardness tests performed on quartz fibers, as well as the characteristics of the quartz fiber and plate Cerenkov calorimeters that have been built, designed, and proposed for the CMS experiment.

Akgun, U.; Onel, Y. [Department of Physics and Astronomy, University of Iowa, 203 Van Allen Hall, Iowa City, IA, 52242 (United States)

2006-10-27T23:59:59.000Z

206

Stack Monitor Operating Experience Review  

Science Conference Proceedings (OSTI)

Stack monitors are used to sense radioactive particulates and gases in effluent air being vented from rooms of nuclear facilities. These monitors record the levels and types of effluents to the environment. This paper presents the results of a stack monitor operating experience review of the U.S. Department of Energy (DOE) Occurrence Reporting and Processing System (ORPS) database records from the past 18 years. Regulations regarding these monitors are briefly described. Operating experiences reported by the U.S. DOE and in engineering literature sources were reviewed to determine the strengths and weaknesses of these monitors. Electrical faults, radiation instrumentation faults, and human errors are the three leading causes of failures. A representative all modes failure rate is 1E-04/hr. Repair time estimates vary from an average repair time of 17.5 hours (with spare parts on hand) to 160 hours (without spare parts on hand). These data should support the use of stack monitors in any nuclear facility, including the National Ignition Facility and the international ITER project.

L. C. Cadwallader; S. A. Bruyere

2009-05-01T23:59:59.000Z

207

Experiment Hall & Beamline | Advanced Photon Source  

NLE Websites -- All DOE Office Websites (Extended Search)

Experiment Hall & Beamlines The ratchet-shaped radiation-shielding wall between the APS storage ring and the experiment hall serves as a line of demarcation. Thirty-five "sectors"...

208

Definition of Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Gamma Radiation and X-Rays Beta Radiation Alpha Radiation Irradiation Radioactive Contamination Definitions Detection Measurement Safety Around Radiation Sources Types of...

209

How to Detect Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

How to Detect Radiation How to Survey Measurement Safety Around Radiation Sources Types of Radiation Exposure Managing Radiation Emergencies Procedure Demonstration Detection How...

210

Health Risks Associated with Low Doses of Radiation  

Science Conference Proceedings (OSTI)

Despite a wealth of information, there remains uncertainty concerning human radiation effects at low dose levels. This report provides background information and a literature review of research on the potential health hazards associated with exposure to low-level ionizing radiation. Topics include radiation characteristics, protection standards, epidemiologic data and risk models, the nature of human health exposure-related effects, important radiation health studies to date, and the scientific method fo...

1994-09-17T23:59:59.000Z

211

Radiation dosimeter  

DOE Patents (OSTI)

A radiation detector readout circuit is provided which produces a radiation dose-rate readout from a detector even though the detector output may be highly energy dependent. A linear charge amplifier including an output charge pump circuit amplifies the charge signal pulses from the detector and pumps the charge into a charge storage capacitor. The discharge rate of the capacitor through a resistor is controlled to provide a time-dependent voltage which when integrated provides an output proportional to the dose-rate of radiation detected by the detector. This output may be converted to digital form for readout on a digital display.

Fox, Richard J. (Oak Ridge, TN)

1983-01-01T23:59:59.000Z

212

Radiation dosimeter  

DOE Patents (OSTI)

A radiation detector readout circuit is provided which produces a radiation dose-rate readout from a detector even through the detector output may be highly energy dependent. A linear charge amplifier including an output charge pump circuit amplifies the charge signal pulses from the detector and pumps the charge into a charge storage capacitor. The discharge rate of the capacitor through a resistor is controlled to provide a time-dependent voltage which when integrated provides an output proportional to the dose-rate of radiation detected by the detector. This output may be converted to digital form for readout on a digital display.

Fox, R.J.

1981-09-01T23:59:59.000Z

213

Radiation Hydrodynamics  

DOE Green Energy (OSTI)

The discipline of radiation hydrodynamics is the branch of hydrodynamics in which the moving fluid absorbs and emits electromagnetic radiation, and in so doing modifies its dynamical behavior. That is, the net gain or loss of energy by parcels of the fluid material through absorption or emission of radiation are sufficient to change the pressure of the material, and therefore change its motion; alternatively, the net momentum exchange between radiation and matter may alter the motion of the matter directly. Ignoring the radiation contributions to energy and momentum will give a wrong prediction of the hydrodynamic motion when the correct description is radiation hydrodynamics. Of course, there are circumstances when a large quantity of radiation is present, yet can be ignored without causing the model to be in error. This happens when radiation from an exterior source streams through the problem, but the latter is so transparent that the energy and momentum coupling is negligible. Everything we say about radiation hydrodynamics applies equally well to neutrinos and photons (apart from the Einstein relations, specific to bosons), but in almost every area of astrophysics neutrino hydrodynamics is ignored, simply because the systems are exceedingly transparent to neutrinos, even though the energy flux in neutrinos may be substantial. Another place where we can do ''radiation hydrodynamics'' without using any sophisticated theory is deep within stars or other bodies, where the material is so opaque to the radiation that the mean free path of photons is entirely negligible compared with the size of the system, the distance over which any fluid quantity varies, and so on. In this case we can suppose that the radiation is in equilibrium with the matter locally, and its energy, pressure and momentum can be lumped in with those of the rest of the fluid. That is, it is no more necessary to distinguish photons from atoms, nuclei and electrons, than it is to distinguish hydrogen atoms from helium atoms, for instance. There are all just components of a mixed fluid in this case. So why do we have a special subject called ''radiation hydrodynamics'', when photons are just one of the many kinds of particles that comprise our fluid? The reason is that photons couple rather weakly to the atoms, ions and electrons, much more weakly than those particles couple with each other. Nor is the matter-radiation coupling negligible in many problems, since the star or nebula may be millions of mean free paths in extent. Radiation hydrodynamics exists as a discipline to treat those problems for which the energy and momentum coupling terms between matter and radiation are important, and for which, since the photon mean free path is neither extremely large nor extremely small compared with the size of the system, the radiation field is not very easy to calculate. In the theoretical development of this subject, many of the relations are presented in a form that is described as approximate, and perhaps accurate only to order of {nu}/c. This makes the discussion cumbersome. Why are we required to do this? It is because we are using Newtonian mechanics to treat our fluid, yet its photon component is intrinsically relativistic; the particles travel at the speed of light. There is a perfectly consistent relativistic kinetic theory, and a corresponding relativistic theory of fluid mechanics, which is perfectly suited to describing the photon gas. But it is cumbersome to use this for the fluid in general, and we prefer to avoid it for cases in which the flow velocity satisfies {nu} << c. The price we pay is to spend extra effort making sure that the source-sink terms relating to our relativistic gas component are included in the equations of motion in a form that preserves overall conservation of energy and momentum, something that would be automatic if the relativistic equations were used throughout.

Castor, J I

2003-10-16T23:59:59.000Z

214

Low Dose Radiation Research Program: Genomic Instability and...  

NLE Websites -- All DOE Office Websites (Extended Search)

Genomic Instability and Low Dose Low Dose Rate Radiation. Authors: Lei Huang, Suzanne Grim, William F. Morgan Institutions: University of Maryland. Humans will always receive...

215

Low Dose Radiation Research Program: Susan S. Wallace  

NLE Websites -- All DOE Office Websites (Extended Search)

Susan S. Wallace University of Vermont Past Funded Project Free Radical DNA Damage Produced Endogenously and by Low Dose Radiation in Human Cells: Quantitation, Consequences, and...

216

RADIATION DETECTOR  

DOE Patents (OSTI)

A radiation detector of the type is described wherein a condenser is directly connected to the electrodes for the purpose of performing the dual function of a guard ring and to provide capacitance coupling for resetting the detector system.

Wilson, H.N.; Glass, F.M.

1960-05-10T23:59:59.000Z

217

NIST Radiation thermometry  

Science Conference Proceedings (OSTI)

Radiation thermometry. Summary: ... Description: Radiation thermometers are calibrated using a range of variable-temperature blackbodies. ...

2011-10-13T23:59:59.000Z

218

NIST Optical Radiation Group  

Science Conference Proceedings (OSTI)

Optical Radiation Group. Welcome. The Optical Radiation Group maintains, improves, and disseminates the national scales ...

2013-07-29T23:59:59.000Z

219

Carcinogenesis and low-level ionizing radiation with special reference to lung cancer and exposure to radon daughters  

SciTech Connect

Of the important health effects of ionizing radiation, three important late effects - carcinogenesis, teratogenesis and mutagenesis are of greatest concern. This is because any exposure, even at low levels, carries some risk of such deleterious effects. As the dose of radiation increases above very low levels, the risk of health effects increases. Cancer-induction is the most important late somatic effect of low-dose ionizing radiation. Solid cancers, rather than leukemia, are principal late effects in exposed individuals. Tissues vary greatly in their susceptibility to radiation carcinogenesis. The most frequently occurring radiation-induced cancers in man include, in decreasing order of susceptibility: the female breast, the thyroid gland, the blood-forming tissues, the lung, certain organs of the gastrointestinal tract, and the bones. A number of biological and physical factors affect the cancer risk, such as age, sex, life-style, LET, and RBE. Despite uncertainty about low-level radiation risks, regulatory and advisory bodies must set standards for exposure, and individuals need information to be able to make informed judgments for themselves. From the point of view of the policy maker, the overriding concern is the fact that small doses of radiation can cause people to have more cancers than would otherwise be expected. While concern for all radiation effects exists, our human experience is limited to cancer-induction in exposed populations. This discussion is limited to cancer risk estimation and decision-making in relation to the health effects on populations of exposure to low levels of ionizing radiation. Here, low-level radiation will refer to yearly whole-body doses up to 5 rems or 0.05 Sv, or to cumulative doses up to 50 rems or 0.5 Sv from low-LET radiation and from high-LET radiation. (ERB)

Fabrikant, J.I.

1982-04-01T23:59:59.000Z

220

RADIATION SAFETY POLICY Effective Date: April 4, 2012 Originating Office: Office of the  

E-Print Network (OSTI)

radiation exposure "As Low as Reasonably Achievable" "Internal Radiation Permit" ("IRP") means and the general public from unnecessary or potentially harmful levels of radiation exposure. PURPOSE capable of generating X or Gamma radiation "Radiology" involves external exposure of humans to Radiation

Doedel, Eusebius

Note: This page contains sample records for the topic "human radiation experiments" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


221

Longwave Cloud Radiative Forcing as Determined from Nimbus-7 Observations  

Science Conference Proceedings (OSTI)

Collocated and coincident cloud and outgoing longwave radiation observations taken by experiments on board the Nimbus-7 satellite have been used to infer the daytime longwave cloud-radiative forcing. Through the specification of a time-series of ...

Philip E. Ardanuy; Larry L. Stowe; Arnold Gruber; Mitchell Weiss; Craig S. Long

1989-08-01T23:59:59.000Z

222

The Sensitivity of the Tropical-Mean Radiation Budget  

Science Conference Proceedings (OSTI)

A key disagreement exists between global climate model (GCM) simulations and satellite observations of the decadal variability in the tropical-mean radiation budget. Measurements from the Earth Radiation Budget Experiment (ERBE) over the period ...

Amy C. Clement; Brian Soden

2005-08-01T23:59:59.000Z

223

Entrainment into a Stratocumulus Layer with Distributed Radiative Cooling  

Science Conference Proceedings (OSTI)

It is shown that the radiative cooling of a cloud layer strongly influences the turbulent flux profiles and the entrainment rate, and that the radiative cooling should be modeled as acting inside the turbulent layer. Numerical experiments ...

David A. Randall

1980-01-01T23:59:59.000Z

224

Uncertainties in the Radiative Forcing Due to Sulfate Aerosols  

Science Conference Proceedings (OSTI)

Radiative transfer calculations based on a new sulfate distribution from a chemistry-transport model simulation have been performed. A wide range of sensitivity experiments have been performed to illustrate the large uncertainty in the radiative ...

Gunnar Myhre; Frode Stordal; Tore F. Berglen; Jostein K. Sundet; Ivar S. A. Isaksen

2004-03-01T23:59:59.000Z

225

Investigation of Aerosol Sources, Lifetime and Radiative Forcing through Multi-Instrument Data Assimilation  

E-Print Network (OSTI)

as clouds reflect solar radiation and trap outgoing CHAPTEReffectively scatter solar radiation, such as sulfate, reduceF o = 1361W/m 2 (Solar Radiation and Climate Experiement (

Rubin, Juli Irene

2012-01-01T23:59:59.000Z

226

Modeling Tropical Pacific Sea Surface Temperature with Satellite-Derived Solar Radiative Forcing  

Science Conference Proceedings (OSTI)

Two independent datasets for the solar radiation at the surface derived from satellites are compared. The data derived from the Earth Radiation Budget Experiment (ERBE) is for the net solar radiation at the surface whereas the International ...

Richard Seager; M. Benno Blumenthal

1994-12-01T23:59:59.000Z

227

Sandia Laboratories radiation facilities. Second edition  

SciTech Connect

This brochure is designed as a basic source of information for prospective users of Sandia Laboratories Radiation Facilities. It contains a brief description of the various major radiation sources, a summary of their output characteristics, and additional information useful to experimenters. Radiation source development and source upgrading is an ongoing program, with new source configurations and modes of operation continually being devised to satisfy the ever-changing radiation requirements of the users. For most cases, the information presented here should allow a potential user to assess the applicability of a particular radiation facility to a proposed experiment and to permit some preirradiation calculations and planning.

Choate, L.M.; Schmidt, T.R.

1979-07-01T23:59:59.000Z

228

Radiation receiver  

SciTech Connect

The apparatus for collecting radiant energy and converting same to alternate energy form includes a housing having an interior space and a radiation transparent window allowing, for example, solar radiation to be received in the interior space of the housing. Means are provided for passing a stream of fluid past said window and for injecting radiation absorbent particles in said fluid stream. The particles absorb the radiation and because of their very large surface area, quickly release the heat to the surrounding fluid stream. The fluid stream particle mixture is heated until the particles vaporize. The fluid stream is then allowed to expand in, for example, a gas turbine to produce mechanical energy. In an aspect of the present invention properly sized particles need not be vaporized prior to the entrance of the fluid stream into the turbine, as the particles will not damage the turbine blades. In yet another aspect of the invention, conventional fuel injectors are provided to inject fuel into the fluid stream to maintain the proper temperature and pressure of the fluid stream should the source of radiant energy be interrupted. In yet another aspect of the invention, an apparatus is provided which includes means for providing a hot fluid stream having hot particles disbursed therein which can radiate energy, means for providing a cooler fluid stream having cooler particles disbursed therein, which particles can absorb radiant energy and means for passing the hot fluid stream adjacent the cooler fluid stream to warm the cooler fluid and cooler particles by the radiation from the hot fluid and hot particles.

Hunt, Arlon J. (Oakland, CA)

1983-01-01T23:59:59.000Z

229

Radiation receiver  

DOE Patents (OSTI)

The apparatus for collecting radiant energy and converting same to alternate energy form includes a housing having an interior space and a radiation transparent window allowing, for example, solar radiation to be received in the interior space of the housing. Means are provided for passing a stream of fluid past said window and for injecting radiation absorbent particles in said fluid stream. The particles absorb the radiation and because of their very large surface area, quickly release the heat to the surrounding fluid stream. The fluid stream particle mixture is heated until the particles vaporize. The fluid stream is then allowed to expand in, for example, a gas turbine to produce mechanical energy. In an aspect of the present invention properly sized particles need not be vaporized prior to the entrance of the fluid stream into the turbine, as the particles will not damage the turbine blades. In yet another aspect of the invention, conventional fuel injectors are provided to inject fuel into the fluid stream to maintain the proper temperature and pressure of the fluid stream should the source of radiant energy be interrupted. In yet another aspect of the invention, an apparatus is provided which includes means for providing a hot fluid stream having hot particles disbursed therein which can radiate energy, means for providing a cooler fluid stream having cooler particles disbursed therein, which particles can absorb radiant energy and means for passing the hot fluid stream adjacent the cooler fluid stream to warm the cooler fluid and cooler particles by the radiation from the hot fluid and hot particles. 5 figs.

Hunt, A.J.

1983-09-13T23:59:59.000Z

230

RADIATION SOURCES  

DOE Patents (OSTI)

A novel long-lived source of gamma radiation especially suitable for calibration purposes is described. The source of gamma radiation is denoted mock iodine131, which comprises a naixture of barium-133 and cesium-137. The barium and cesium are present in a barium-cesium ratio of approximately 5.7/1 to 14/1, uniformly dispersed in an ion exchange resin and a filter surrounding the resin comprised of a material of atomic number below approximately 51, and substantially 0.7 to 0.9 millimeter thick.

Brucer, M.H.

1958-04-15T23:59:59.000Z

231

Low Dose Radiation Research Program: DNA Damage in Acutely Irradiated F2  

NLE Websites -- All DOE Office Websites (Extended Search)

DNA Damage in Acutely Irradiated F2 Mice with a History of Paternal DNA Damage in Acutely Irradiated F2 Mice with a History of Paternal F0 Germline Irradiation Authors: J.E. Baulch and O.G. Raabe Institutions: Center for Health and the Environment, University of California, Davis, CA. The main goal of this grant is to evaluate heritable, transgenerational effects of low dose, low-linear-energy-transfer (LET) radiation (0.1 Gy attenuated 137Cs gamma rays) on Type B spermatogonia in 129SVE mice; wild-type and heterozygous for Ataxia-telangiectasia (AT). The ATM heterozygotes are carriers for a genetic mutation (AT mutated, ATM) that is thought to predispose both humans and mice to radiation sensitivity. Experiments conducted in our laboratory have demonstrated heritable effects of paternal germline exposure to ionizing radiation in mice using 1.0 Gy of

232

Radiation Leukaemongenesis at Low Doses  

NLE Websites -- All DOE Office Websites (Extended Search)

Leukaemongenesis at Low Doses Leukaemongenesis at Low Doses Simon Bouffler Health Protection Agency Abstract Myeloid leukaemias feature prominently among the cancers associated with human exposures to ionising radiation. The CBA mouse model of radiation-induced acute myeloid leukaemia (AML) has been used extensively for both quantitative and mechanistic studies. Loss of genetic material from chromosome 2 (chr2) is known to be associated with most radiation-induced AMLs. AML develops in CBA mice exposed to X- or γ-radiation, after a mean latency period of 18 months, with a maximal incidence of approximately 25% at 3Gy. A strong candidate AML-suppressor gene located within the commonly deleted region of chr2 has been identified, Sƒpil/PU.1. This gene suffers hemizygous loss and specific

233

Medical applications of synchrotron radiation  

SciTech Connect

Ever since the first diagnostic x-ray was done in the United States on February 3, 1896, the application of ionizing radiation to the field of medicine has become increasingly important. Both in clinical medicine and basic research the use of x-rays for diagnostic imaging and radiotherapy is now widespread. Radiography, angiography, CAT and PETT scanning, mammography, and nuclear medicine are all examples of technologies developed to image the human anatomy. In therapeutic applications, both external and internal sources of radiation are applied to the battle against cancer. The development of dedicated synchrotron radiation sources has allowed exciting advances to take place in many of these applications. The new sources provide tunable, high-intensity monochromatic beams over a wide range of energies which can be tailored to specific programmatic needs. This paper surveys those areas of medical research in which synchrotron radiation facilities are actively involved.

Thomlinson, W.

1991-10-01T23:59:59.000Z

234

Medical Applications of Synchrotron Radiation  

DOE R&D Accomplishments (OSTI)

Ever since the first diagnostic x-ray was done in the United States on February 3, 1896, the application of ionizing radiation to the field of medicine has become increasingly important. Both in clinical medicine and basic research the use of x-rays for diagnostic imaging and radiotherapy is now widespread. Radiography, angiography, CAT and PETT scanning, mammography, and nuclear medicine are all examples of technologies developed to image the human anatomy. In therapeutic applications, both external and internal sources of radiation are applied to the battle against cancer. The development of dedicated synchrotron radiation sources has allowed exciting advances to take place in many of these applications. The new sources provide tunable, high-intensity monochromatic beams over a wide range of energies which can be tailored to specific programmatic needs. This paper surveys those areas of medical research in which synchrotron radiation facilities are actively involved.

Thomlinson, W.

1991-10-00T23:59:59.000Z

235

Low Dose Radiation Program: Links - Online Literature  

NLE Websites -- All DOE Office Websites (Extended Search)

Online Literature Online Literature Journals, Books and other Publications Armed Forces Radiobiology Research Institute Chornobyl Center for Nuclear Safety Radioactive Waste and Radioecology "Insight" Magazine Central Research Institute of the Electric Power Industry (CRIEPI) News: Aiming at an information center on low dose radiation research Health Physics International Journal of Radiation Biology Iranian Journal of Radiation Research Journal of Radiological Protection National Council on Radiation Protection and Measurements Radiation Research U.S. Department of Energy (DOE) Information Bridge Reports Animal Cancer Tests and Human Cancer Risk Assessment: A Broad Perspective Effects of Ionizing Radiation: Atomic Bomb Survivors and Their Children (1945-1995) Health Effects of Exposure to Low Levels of Ionizing Radiation: BEIR

236

BNL | Completed ATF Experiments  

NLE Websites -- All DOE Office Websites (Extended Search)

Completed / Terminated ATF Experiments Completed / Terminated ATF Experiments AE01 - Micro-undulator FEL Experiment. Spokesperson: I. Ben-Zvi, BNL. (1992 - 1997) AE02. - Inverse FEL Accelerator. Spokesperson: A. van Steenbergen, BNL. [Yale, Columbia]. (1992-1997) AE03 - Laser Grating Accelerator Experiment. Spokesperson: R. Fernow, BNL. [Princeton, LANL]. (1992- 1996) AE05 - Nonlinear-Compton Scattering. Spokesperson: K. McDonald, Princeton (1992-) AE06 - Inverse Cherenkov Acceleration. Spokesperson: W. Kimura, STI Optronics. [UCSB,BNL]. (1992-1997) AE08 - Far Infrared Radiation Source. Spokesperson J. Walsh, Dartmouth. [Oxford, BNL]. (1992 - 1994) AE09. - Photocathode R&D. Spokesperson: T. Rao, BNL. (1992 - ) AE10. - High Gain Harmonic Generation FEL. Spokesperson: L.H. Yu, BNL. [ANL] (1992 - 2001)

237

Irradiation Effects on Human Cortical Bone Fracture Behavior  

NLE Websites -- All DOE Office Websites (Extended Search)

Irradiation Effects on Human Irradiation Effects on Human Cortical Bone Fracture Behavior Irradiation Effects on Human Cortical Bone Fracture Behavior Print Wednesday, 28 July 2010 00:00 Human bone is strong but still fallible. To better predict fracturing in bone, researchers need a mechanistic framework to understand the changes taking place on different size scales within bone, as well as the role of sustained irradiation damage. Combining in situ mechanical testing with synchrotron x-ray diffraction imaging and/or tomography, is a popular method of investigating micrometer deformation and fracture behavior in bone. However, the role that irradiation plays in these high-exposure experiments, and how it affects the properties of bone tissue, are not yet fully understood. A team of researchers led by Robert O. Ritchie at the Lawrence Berkeley National Laboratory and the University of California, Berkeley used synchrotron radiation micro-tomography at Advanced Light Source Beamline 8.3.2 to investigate changes in crack path and toughening mechanisms in human cortical bone with increased exposure to radiation, finding that exposure to high levels of irradiation can lead to drastic losses in strength, ductility, and toughness.

238

Radiation Protection Act (Pennsylvania)  

Energy.gov (U.S. Department of Energy (DOE))

This Act combines the radiation safety provisions of The Atomic Energy Development and Radiation Control Act and the Environmental Radiation Protection Act, and empowers the Department of...

239

Radiation Tolerant Metallic Multilayers  

Science Conference Proceedings (OSTI)

Strategies that can alleviate radiation damage may assist the design of radiation tolerant materials. We will summarize our recent studies on radiation damage in...

240

NEW SOURCES OF RADIATION  

E-Print Network (OSTI)

Stanford Synchrotron Radiation Project Report No. 75/07.IBL 79M0733 Fig. 20. Radiation emission pattern by electronsWinick, Stanford Synchrotron Radiation Laboratory. Fig. 21.

Schimmerling, W.

2010-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "human radiation experiments" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


241

Radiation-induced angiosarcoma  

E-Print Network (OSTI)

1a Figure 1b Figure 1. Radiation-induced angiosarcoma in afollowing completion of radiation therapy. Figure 2a Figurecell histiocytosis after radiation for breast carcinoma: can

Anzalone, C Lane; Cohen, Philip R; Diwan, Abdul H; Prieto, Victor G

2013-01-01T23:59:59.000Z

242

Probing Radiative Solar Neutrinos Decays  

E-Print Network (OSTI)

Motivated by a pilot experiment conducted by F.Vannucci et al. during a solar eclipse, we work out the geometry governing the radiative decays of solar neutrinos. Surprisingly, although a smaller proportion of the photons can be detected, the case of strongly non-degenerate neutrinos brings better limits in terms of the fundamental couplings. We advocate satellite-based experiments to improve the sensitivity.

Frre, J M

1998-01-01T23:59:59.000Z

243

Radiation properties of cavity Cerenkov radiation  

SciTech Connect

Cerenkov radiation from cavities has been analyzed by quantum electrodynamic theory. Analytical expressions of basic radiation properties such as the Einstein's A and B coefficients are derived and shown to be directly modified by the cavities. The analysis leads to the conclusion that the coherent radiation from the Cerenkov radiation devices is due to super radiance of spontaneous emission instead of stimulated emission. Coherent and incoherent radiations are analyzed in the THz radiation range.

Gao Ju; Shen Fang [Electrical and Computer Engineering Department, University of Illinois, Urbana, Illinois 61801 (United States)

2006-04-15T23:59:59.000Z

244

Decomposition of radiational effects of model feedbacks  

SciTech Connect

Three separate doubled CO/sub 2/ experiments with the statistical dynamic model are used to illustrate efforts to study the climate dynamics, feedbacks, and interrelationships of meteorological parameters by decomposing and isolating their individual effects on radiation transport.

Ellsaesser, H.W.; MacCracken, M.C.; Potter, G.L.; Mitchell, C.S.

1981-08-01T23:59:59.000Z

245

Minimizing Errors Associated with Multiplate Radiation Shields  

Science Conference Proceedings (OSTI)

Multiplate radiation shield errors are examined using the following techniques: 1) ray tracing analysis, 2) wind tunnel experiments, 3) numerical flow simulations, and 4) field testing. The authors objectives are to develop guidelines for ...

Scott J. Richardson; Fred V. Brock; Steven R. Semmer; Cathy Jirak

1999-11-01T23:59:59.000Z

246

Annual Cycle of Surface Longwave Radiation  

Science Conference Proceedings (OSTI)

The annual cycles of upward and downward longwave fluxes at the earths surface are investigated by use of the NASA Global Energy and Water Cycle Experiment (GEWEX) Surface Radiation Budget Dataset. Principal component analysis is used to quantify ...

Pamela E. Mlynczak; G. Louis Smith; Anne C. Wilber; Paul W. Stackhouse

2011-06-01T23:59:59.000Z

247

Travel for the 2004 American Statistical Association Biannual Radiation Meeting: "Radiation in Realistic Environments: Interactions Between Radiation and Other Factors  

SciTech Connect

The 16th ASA Conference on Radiation and Health, held June 27-30, 2004 in Beaver Creek, CO, offered a unique forum for discussing research related to the effects of radiation exposures on human health in a multidisciplinary setting. The Conference furnishes investigators in health related disciplines the opportunity to learn about new quantitative approaches to their problems and furnishes statisticians the opportunity to learn about new applications for their discipline. The Conference was attended by about 60 scientists including statisticians, epidemiologists, biologists and physicists interested in radiation research. For the first time, ten recipients of Young Investigator Awards participated in the conference. The Conference began with a debate on the question: Do radiation doses below 1 cGy increase cancer risks? The keynote speaker was Dr. Martin Lavin, who gave a banquet presentation on the timely topic How important is ATM? The focus of the 2004 Conference on Radiation and Health was Radiation in Realistic Environments: Interactions Between Radiation and Other Risk Modifiers. The sessions of the conference included: Radiation, Smoking, and Lung Cancer Interactions of Radiation with Genetic Factors: ATM Radiation, Genetics, and Epigenetics Radiotherapeutic Interactions The Conference on Radiation and Health is held bi-annually, and participants are looking forward to the 17th conference to be held in 2006.

Brenner, David J.

2009-07-21T23:59:59.000Z

248

Chapter 5 -- Experiments with Plutonium, Uranium, and Polonium  

NLE Websites -- All DOE Office Websites (Extended Search)

5: Experiments With Plutonium, Uranium, and Polonium Introduction The Manhattan District Experiments The AEC's Reaction: Preserving Secrecy while Requiring Disclosure Human...

249

Types of Radiation Exposure  

NLE Websites -- All DOE Office Websites (Extended Search)

External Irradiation Contamination Incorporation Biological Effects of Acute, Total Body Irradiation Managing Radiation Emergencies Procedure Demonstration Types of radiation...

250

Radiation Effects In Ceramics  

Science Conference Proceedings (OSTI)

RADIATION MATERIALS SCIENCE IN TECHNOLOGY APPLICATIONS II: Radiation Effects in Ceramics. Sponsored by: Jt. SMD/MSD Nuclear Materials...

251

Ionizing Radiation Dosimetry  

Science Conference Proceedings (OSTI)

Ionizing Radiation Dosimetry. ... OH. US Air Force Radiation Dosimetry Laboratory, Wright-Patterson - Base, OH [100548- 0] PA. ...

2013-09-06T23:59:59.000Z

252

Radiation Physics Division  

Science Conference Proceedings (OSTI)

... The Radiation Physics Division, part of the Physical Measurement Laboratory ... the measurement standards for ionizing radiations and radioactivity ...

2013-09-05T23:59:59.000Z

253

Cellular and molecular level responses after radiofrequency radiation exposure, alone or in combination with x-rays or chemicals. Final report, 1 April 1991-30 September 1994  

SciTech Connect

This project was initiated to explore the potential bioeffects of microwave radiation, alone or in combination with ionizing radiation and chemicals. Over the time period of the project, an automated thermal control system, to be used for maintaining the temperature in tissue culture medium during microwave exposures, was designed, constructed, and software was created. While this was underway during the project period, numerous positive control biological experiments were performed on two different cell types, the Epstein Barr Virus transformed 244B human lymphoblastoid cell, and the freshly isolated peripheral human lymphocyte. The 244B cells were used to address the question of whether a physical agent, ionizing radiation, at low doses where cells would predominantly remain viable, would induce the DNA binding protein NF-kB, and/or four immediate early genes (IEG) (protooncogenes).

Meltz, M.L.; Natarajan, M.; Prasad, A.V.

1995-02-21T23:59:59.000Z

254

SLAC National Accelerator Laboratory - SSRL Experiments to Focus...  

NLE Websites -- All DOE Office Websites (Extended Search)

SSRL Experiments to Focus on Solar Tech By Glenn Roberts Jr. November 7, 2012 SLAC's Stanford Synchrotron Radiation Lightsource will play a central role in three research projects...

255

Synchrotron Ultraviolet Radiation Facility SURF III ...  

Science Conference Proceedings (OSTI)

... Synchrotron Radiation. What is Synchrotron Radiation? Synchrotron radiation ... known. Properties of Synchrotron Radiation. Schwinger ...

256

Low Dose Radiation Research Program: Frequencies of Radiation-Induced  

NLE Websites -- All DOE Office Websites (Extended Search)

Frequencies of Radiation-Induced Chromosome Interchanges and Frequencies of Radiation-Induced Chromosome Interchanges and Randomness of Chromosome Territory Locations Relative to One Another. Authors: RK Sachs,§ MN Cornforth,‡ KM Greulich-Bode,* L Hlatky, and DJ Brenner|| Institutions: §Department of Mathematics, University of California, ‡University of Texas Medical Branch, *Department of Skin Carcinogenesis, German Cancer Research Center DFCI, Harvard Medical School, ||Center for Radiological Research, Columbia University. Leukemogenesis, and perhaps carcinogenesis in general, often involves specific chromosome translocations. Radiation-induced chromosome translocation frequencies are strongly influenced by how close participating chromosomes are to one another in an interphase cell nucleus. We sought to determine whether chromosomes in human peripheral blood

257

Mammalian Tissue Response to Low Dose Ionizing Radiation: The Role of Oxidative Metabolism and Intercellular Communication  

SciTech Connect

The objective of the project was to elucidate the mechanisms underlying the biological effects of low dose/low dose rate ionizing radiation in organs/tissues of irradiated mice that differ in their susceptibility to ionizing radiation, and in human cells grown under conditions that mimic the natural in vivo environment. The focus was on the effects of sparsely ionizing cesium-137 gamma rays and the role of oxidative metabolism and intercellular communication in these effects. Four Specific Aims were proposed. The integrated outcome of the experiments performed to investigate these aims has been significant towards developing a scientific basis to more accurately estimate human health risks from exposures to low doses ionizing radiation. By understanding the biochemical and molecular changes induced by low dose radiation, several novel markers associated with mitochondrial functions were identified, which has opened new avenues to investigate metabolic processes that may be affected by such exposure. In particular, a sensitive biomarker that is differentially modulated by low and high dose gamma rays was discovered.

Azzam, Edouard I

2013-01-16T23:59:59.000Z

258

Irradiation Effects on Human Cortical Bone Fracture Behavior  

NLE Websites -- All DOE Office Websites (Extended Search)

Irradiation Effects on Human Cortical Bone Fracture Behavior Print Irradiation Effects on Human Cortical Bone Fracture Behavior Print Human bone is strong but still fallible. To better predict fracturing in bone, researchers need a mechanistic framework to understand the changes taking place on different size scales within bone, as well as the role of sustained irradiation damage. Combining in situ mechanical testing with synchrotron x-ray diffraction imaging and/or tomography, is a popular method of investigating micrometer deformation and fracture behavior in bone. However, the role that irradiation plays in these high-exposure experiments, and how it affects the properties of bone tissue, are not yet fully understood. A team of researchers led by Robert O. Ritchie at the Lawrence Berkeley National Laboratory and the University of California, Berkeley used synchrotron radiation micro-tomography at Advanced Light Source Beamline 8.3.2 to investigate changes in crack path and toughening mechanisms in human cortical bone with increased exposure to radiation, finding that exposure to high levels of irradiation can lead to drastic losses in strength, ductility, and toughness.

259

Irradiation Effects on Human Cortical Bone Fracture Behavior  

NLE Websites -- All DOE Office Websites (Extended Search)

Irradiation Effects on Human Cortical Bone Fracture Behavior Print Irradiation Effects on Human Cortical Bone Fracture Behavior Print Human bone is strong but still fallible. To better predict fracturing in bone, researchers need a mechanistic framework to understand the changes taking place on different size scales within bone, as well as the role of sustained irradiation damage. Combining in situ mechanical testing with synchrotron x-ray diffraction imaging and/or tomography, is a popular method of investigating micrometer deformation and fracture behavior in bone. However, the role that irradiation plays in these high-exposure experiments, and how it affects the properties of bone tissue, are not yet fully understood. A team of researchers led by Robert O. Ritchie at the Lawrence Berkeley National Laboratory and the University of California, Berkeley used synchrotron radiation micro-tomography at Advanced Light Source Beamline 8.3.2 to investigate changes in crack path and toughening mechanisms in human cortical bone with increased exposure to radiation, finding that exposure to high levels of irradiation can lead to drastic losses in strength, ductility, and toughness.

260

Irradiation Effects on Human Cortical Bone Fracture Behavior  

NLE Websites -- All DOE Office Websites (Extended Search)

Irradiation Effects on Human Cortical Bone Fracture Behavior Print Irradiation Effects on Human Cortical Bone Fracture Behavior Print Human bone is strong but still fallible. To better predict fracturing in bone, researchers need a mechanistic framework to understand the changes taking place on different size scales within bone, as well as the role of sustained irradiation damage. Combining in situ mechanical testing with synchrotron x-ray diffraction imaging and/or tomography, is a popular method of investigating micrometer deformation and fracture behavior in bone. However, the role that irradiation plays in these high-exposure experiments, and how it affects the properties of bone tissue, are not yet fully understood. A team of researchers led by Robert O. Ritchie at the Lawrence Berkeley National Laboratory and the University of California, Berkeley used synchrotron radiation micro-tomography at Advanced Light Source Beamline 8.3.2 to investigate changes in crack path and toughening mechanisms in human cortical bone with increased exposure to radiation, finding that exposure to high levels of irradiation can lead to drastic losses in strength, ductility, and toughness.

Note: This page contains sample records for the topic "human radiation experiments" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


261

Irradiation Effects on Human Cortical Bone Fracture Behavior  

NLE Websites -- All DOE Office Websites (Extended Search)

Irradiation Effects on Human Cortical Bone Fracture Behavior Print Irradiation Effects on Human Cortical Bone Fracture Behavior Print Human bone is strong but still fallible. To better predict fracturing in bone, researchers need a mechanistic framework to understand the changes taking place on different size scales within bone, as well as the role of sustained irradiation damage. Combining in situ mechanical testing with synchrotron x-ray diffraction imaging and/or tomography, is a popular method of investigating micrometer deformation and fracture behavior in bone. However, the role that irradiation plays in these high-exposure experiments, and how it affects the properties of bone tissue, are not yet fully understood. A team of researchers led by Robert O. Ritchie at the Lawrence Berkeley National Laboratory and the University of California, Berkeley used synchrotron radiation micro-tomography at Advanced Light Source Beamline 8.3.2 to investigate changes in crack path and toughening mechanisms in human cortical bone with increased exposure to radiation, finding that exposure to high levels of irradiation can lead to drastic losses in strength, ductility, and toughness.

262

The Mixed-Phase Arctic Cloud Experiment  

Science Conference Proceedings (OSTI)

The Mixed-Phase Arctic Cloud Experiment (M-PACE) was conducted from 27 September through 22 October 2004 over the Department of Energy's Atmospheric Radiation Measurement (ARM) Climate Research Facility (ACRF) on the North Slope of Alaska. The ...

J. Verlinde; J. Y. Harrington; V. T. Yannuzzi; A. Avramov; S. Greenberg; S. J. Richardson; C. P. Bahrmann; G. M. McFarquhar; G. Zhang; N. Johnson; M. R. Poellot; J. H. Mather; D. D. Turner; E. W. Eloranta; D. C. Tobin; R. Holz; B. D. Zak; M. D. Ivey; A. J. Prenni; P. J. DeMott; J. S. Daniel; G. L. Kok; K. Sassen; D. Spangenberg; P. Minnis; T. P. Tooman; M. Shupe; A. J. Heymsfield; R. Schofield

2007-02-01T23:59:59.000Z

263

Modeling human risk: Cell & molecular biology in context  

SciTech Connect

It is anticipated that early in the next century manned missions into outer space will occur, with a mission to Mars scheduled between 2015 and 2020. However, before such missions can be undertaken, a realistic estimation of the potential risks to the flight crews is required. One of the uncertainties remaining in this risk estimation is that posed by the effects of exposure to the radiation environment of outer space. Although the composition of this environment is fairly well understood, the biological effects arising from exposure to it are not. The reasons for this are three-fold: (1) A small but highly significant component of the radiation spectrum in outer space consists of highly charged, high energy (HZE) particles which are not routinely experienced on earth, and for which there are insufficient data on biological effects; (2) Most studies on the biological effects of radiation to date have been high-dose, high dose-rate, whereas in space, with the exception of solar particle events, radiation exposures will be low-dose, low dose-rate; (3) Although it has been established that the virtual absence of gravity in space has a profound effect on human physiology, it is not clear whether these effects will act synergistically with those of radiation exposure. A select panel will evaluate the utilizing experiments and models to accurately predict the risks associated with exposure to HZE particles. Topics of research include cellular and tissue response, health effects associated with radiation damage, model animal systems, and critical markers of Radiation response.

1997-06-01T23:59:59.000Z

264

Radiation Safety  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Brotherhood of Locomotive Brotherhood of Locomotive Engineers & Trainmen Scott Palmer BLET Radiation Safety Officer New Hire Training New Hire study topics * GCOR * ABTH * SSI * Employee Safety * HazMat * Railroad terminology * OJT * 15-week class * Final test Hazardous Materials * Initial new-hire training * Required by OSHA * No specified class length * Open book test * Triennial module Locomotive Engineer Training A little bit older...a little bit wiser... * Typically 2-4 years' seniority * Pass-or-get-fired promotion * Intensive program * Perpetually tested to a higher standard * 20 Weeks of training * 15 of that is OJT * General Code of Operating Rules * Air Brake & Train Handling * System Special Instructions * Safety Instructions * Federal Regulations * Locomotive Simulators * Test Ride * Pass test with 90% Engineer Recertification

265

RADIATION COUNTER  

DOE Patents (OSTI)

This patent relates to a radiation counter, and more particularly, to a scintillation counter having high uniform sensitivity over a wide area and capable of measuring alpha, beta, and gamma contamination over wide energy ranges, for use in quickly checking the contami-nation of personnel. Several photomultiplier tubes are disposed in parallel relationship with a light tight housing behind a wall of scintillation material. Mounted within the housing with the photomultipliers are circuit means for producing an audible sound for each pulse detected, and a range selector developing a voltage proportional to the repetition rate of the detected pulses and automatically altering its time constant when the voltage reaches a predetermined value, so that manual range adjustment of associated metering means is not required.

Goldsworthy, W.W.

1958-02-01T23:59:59.000Z

266

RADIATION DOSIMETER  

DOE Patents (OSTI)

An improvement was made in the determination of amounts of ionizing radiation, particularly low-energy beta particles of less than 1000 rad total dose by means of fluid-phase dosimeter employing a stabilized-- sensitized ferrous-ferric colorimetric system in a sulphuric acid medium. The improvement in the dosimeter consists of adding to the ferrous-ferric system in concentrations of 10/sub -2/ to 10/sup -4/M an organic compound having one or more carboxylic or equivalent groups, such compounds being capable of chelating or complexing the iron ions in the solution. Suitable sensitizing and stabilizing agents are benzoic, phthalic, salicylic, malonic, lactic, maleic, oxalic, citric, succinic, phenolic tartaric, acetic, and adipic acid, as well as other compounds which are added to the solution alone or in certain combinations. As in conventional fluid-phase dosimeters, the absorbed dosage is correlated with a corresponding change in optical density at particular wavelengths of the solution.

Balkwell, W.R. Jr.; Adams, G.D. Jr.

1960-05-10T23:59:59.000Z

267

Low Dose Radiation Program: Workshop VI Abstracts  

NLE Websites -- All DOE Office Websites (Extended Search)

Workshop VI Principal Investigator and Abstracts Workshop VI Principal Investigator and Abstracts Anderson, Carl Whole Genome Analysis of Functional Protein Binding Sites and DNA Methylation: Application to p53 and Low Dose Ionizing Radiation. Averbeck, Dietrich Cellular Responses at Low Doses of Ionizing Radiation. Azzam, Edouard Adaptive Responses to Low Dose/Low Dose-Rate ?-Rays in Normal Human Fibroblasts: The Role of Oxidative Metabolism. Bailey, Susan The Role of Telomere Dysfunction in Driving Genomic Instability. Balajee, Adayabalam Low Dose Radiation Induced DNA Damage Signaling and Repair Responses in Human 3-Dimensional Skin Model System. Barcellos-Hoff, Mary Helen Imaging Bioinformatics for Mapping Multidimensional Responses. Barcellos-Hoff, Mary Helen Biological Response to Radiation Mediated through the Microenvironment and

268

TRIO experiment  

DOE Green Energy (OSTI)

The TRIO experiment is a test of in-situ tritium recovery and heat transfer performance of a miniaturized solid breeder blanket assembly. The assembly (capsule) was monitored for temperature and neutron flux profiles during irradiation and a sweep gas flowed through the capsule to an anaytical train wherein the amounts of tritium in its various chemical forms were determined. The capsule was designed to operate at different temperatures and sweep gas conditions. At the end of the experiment the amount of tritium retained in the solid was at a concentration of less than 0.1 wppM. More than 99.9% of tritium generated during the experiment was successfully recovered. The results of the experiment showed that the tritium inventories at the beginning and at the end of the experiment follow a relationship which appears to be characteristic of intragranular diffusion.

Clemmer, R.G.; Finn, P.A.; Malecha, R.F.; Misra, B.; Billone, M.C.; Bowers, D.L.; Fischer, A.K.; Greenwood, L.R.; Mattas, R.F.; Tam, S.W.

1984-09-01T23:59:59.000Z

269

Dosimetry experiments at the MEDUSA Facility (Little Mountain).  

SciTech Connect

A series of experiments on the MEDUSA linear accelerator radiation test facility were performed to evaluate the difference in dose measured using different methods. Significant differences in dosimeter-measured radiation dose were observed for the different dosimeter types for the same radiation environments, and the results are compared and discussed in this report.

Harper-Slaboszewicz, Victor Jozef; Shaneyfelt, Marty Ray; Sheridan, Timothy J.; Hartman, E. Frederick; Schwank, James Ralph

2010-10-01T23:59:59.000Z

270

Gamma Radiation & X-Rays  

NLE Websites -- All DOE Office Websites (Extended Search)

Gamma Radiation and X-Rays 1. Gamma radiation and X-rays are electromagnetic radiation like visible light, radio waves, and ultraviolet light. These electromagnetic radiations...

271

DETECTORS FOR RADIATION DOSIMETRY  

E-Print Network (OSTI)

2) W. J. Price, "Nuclear Radiation Detection" (2nd ed. , Newand R. J. Berry, "Manual on Radiation Dosimetry" (New York:4) G. F. Knoll, "Radiation Detection and Measurement" (New

Perez-Mendez, V.

2010-01-01T23:59:59.000Z

272

Approved Experiments  

NLE Websites -- All DOE Office Websites (Extended Search)

Cycle 31OCT97 Exp Spokesperson Experiment Title Days 666 Clark Magnetic Rotation in 104Sn 5 667 Janssens Unsafe COULEX of the 240Pu Nucleus 3 670 Smith Exotic Structures in very...

273

Courses on Synchrotron Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Synchrotron Radiation The following is an incomplete list of courses on Synchrotron Radiation. For additional courses, check lightsources.org. XAFS School The APS XAFS School...

274

Radiation Physics Events  

Science Conference Proceedings (OSTI)

NIST Home > Radiation Physics Events. Radiation Physics Events. (showing 1 - 3 of 3). CIRMS 2012 Start Date: 10/22/2012 ...

2011-12-01T23:59:59.000Z

275

Bayesian Radiation Source Localization  

Science Conference Proceedings (OSTI)

Technical Paper / Special Issue on the 16th Biennial Topical Meeting of the Radiation Protection and Shielding Division / Radiation Measurements and General Instrumentation

Kenneth D. Jarman; Erin A. Miller; Richard S. Wittman; Christopher J. Gesh

276

Radiation Control (Virginia)  

Energy.gov (U.S. Department of Energy (DOE))

The Department of Health is responsible for regulating radiation and radioactive materials in the Commonwealth of Virginia. Although the Department's Radiation Control Program primarily focuses on...

277

Solar radiation resource assessment  

DOE Green Energy (OSTI)

The bulletin discusses the following: introduction; Why is solar radiation resource assessment important Understanding the basics; the solar radiation resource assessment project; and future activities.

Not Available

1990-11-01T23:59:59.000Z

278

Determination of Effective Emittance and a Radiatively Equivalent Microphysical Model of Cirrus from Ground-Based and Satellite Observations during the International Cirrus Experiment: The 18 October 1989 Case Study  

Science Conference Proceedings (OSTI)

Ground-based observations and satellite data have been compared for the 18 October 1989 case study of the International Cirrus Experiment (ICE) field campaign. They correspond to thin cirrus clouds with infrared emittances in the range 00.3. ...

G. Brogniez; J. C. Buriez; V. Giraud; F. Parol; C. Vanbauce

1995-04-01T23:59:59.000Z

279

World Wide Web Access to Radiation Datasets for Environmental and Climate Change Studies  

Science Conference Proceedings (OSTI)

Five years of scanner data from the Earth Radiation Budget Experiment (ERBE), eight years of surface radiation budget (SRB) data, and one year of scanner radiation budget data from the FrenchRussianGerman experiment, ScaRaB, will be available ...

T. Dale Bess; Ann B. Carlson; Calvin Mackey; Fredrick M. Denn; Anne Wilber; Nancy Ritchey

2000-11-01T23:59:59.000Z

280

Experience with the Hubble Space Telescope: 20 years of an archetype  

E-Print Network (OSTI)

The Hubble Space Telescope's mission is summarized, with special emphasis placed on the Space Telescope Science Institute's unique experience with Hubble's behavior as an astronomical telescope in the environment of low earth orbit for over two decades. Historical context and background are given, and the project's early scientific expectations are described. A general overview of the spacecraft is followed by a more detailed look at the optical design, both as intended and as built. Basic characteristics of the complete complement of science instruments are also summarized. Experience with the telescope on-orbit is reviewed, starting with the major initial problems, solutions, human servicing missions, and the associated expansion of the observatory's capabilities over this time. Specific attention is then given to understanding Hubble's optical quality and pointing/jitter performance, two fundamental characteristics of a telescope. Experience with-and the important mitigation of-radiation damage and contami...

Lallo, Matthew

2012-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "human radiation experiments" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


281

Human equivalent antenna model for HF exposures: analytical versus numerical approach  

Science Conference Proceedings (OSTI)

In this paper, the human exposure to HF radiation is analyzed using the simplified human equivalent antenna model featuring analytical and numerical approach, respectively. Namely, the human body is represented by an equivalent receiving straight thin ...

Dragan Poljak; Silvestar Sesnic; Ivana Zulim

2009-09-01T23:59:59.000Z

282

RADIATION APPLICATIONS INCORPORATED  

Office of Legacy Management (LM)

. <' ," . . * . RADIATION APPLICATIONS INCORPORATED . 370 Lexl.ngton Avenue New York 17# New York jq.5' L- Contract No. A T (30-l)-2093 with the United States Atom ic Energy Commission F O A M SEPARATION Progress Report for March, 1959 Abstract Appreciable cesium enrichment in the foam has been obtained using the system sodium tetraphenyl boron-Geigy reagent. Enrichment ratios varied from 1.5 to 3.5 depending upon operating conditions. The en- richment appears to depend on the ratio of the sodium tetraphenyl boron to Geigy reagent rather than on the absolute values of the indi- vidual concentrations. Further experiments are being conducted to verify and extend the range of results. Continuous countercurrent column operation has been continued.

283

Low Dose Radiation Program: Radiation Biology and the Radiation Research  

NLE Websites -- All DOE Office Websites (Extended Search)

Biology and the Radiation Research Program Biology and the Radiation Research Program The Department of Energy (DOE) and its predecessor organizations, Energy Research and Development Agency (ERDA) and Atomic Energy Commission (AEC), always have been concerned about the health effects of ionizing radiation. Extensive research has been conducted under their sponsorship at all levels of biological organization from molecules to man. Over the past 60 years, studies using every type of radiation source have included exposure to both external radiation sources and to internally deposited radioactive materials. These exposures used different dose patterns and distributions delivered over a wide range of experimental times. This extensive research provided the basis for the new Low Dose Radiation Research Program, linking

284

Role of ATM kinase in ionizing radiation induced DNA damage response...  

NLE Websites -- All DOE Office Websites (Extended Search)

ATM kinase in ionizing radiation induced DNA damage response in human neural stemprogenitor cells and differentiated cell types Adayabalam Balajee Columbia University Medical...

285

NIST MIRF - Accelerator Radiation Physics  

Science Conference Proceedings (OSTI)

Accelerator Radiation Physics. Medium-energy accelerators are under investigation for production of channeling radiation ...

286

NIST Synchrotron radiation in SSD  

Science Conference Proceedings (OSTI)

Synchrotron radiation in the Sensor Science Division. ... Synchrotron Radiation-Based Calibrations for Space Weather Prediction. ...

2011-10-18T23:59:59.000Z

287

Radiation Detection Instruments  

Science Conference Proceedings (OSTI)

Directory of Accredited Laboratories. Radiation Detection Instruments. In 2005, the Department of Homeland Security requested ...

2013-09-06T23:59:59.000Z

288

Radiation Safety Policy and Procedures Committee  

NLE Websites -- All DOE Office Websites (Extended Search)

RSPPC Meeting Minutes APS only RSPPC Meeting Minutes APS only Radiation Safety Policy and Procedures Committee Charter 1. Purpose The committee reviews functional changes to the Access Control Interlock System (ACIS) and Personnel Protection System (PSS) used to provide personnel protection and area exclusion related to APS accelerators, storage ring and other radiation handling areas. The RSPP Committee advises APS management on radiation safety matters. At the request of APS Management the committee reviews projects, recommends radiation safety policy, and evaluates accident investigation conclusions. 2. Membership Members are appointed by the APS Division Directors and APS Director for their knowledge and background in Interlock Systems, Radiation Safety, Accelerator Operations and Work on the Experiment Floor.

289

Low Dose Radiation Research Program: Howard L. Liber  

NLE Websites -- All DOE Office Websites (Extended Search)

Howard L. Liber Howard L. Liber Department of Environmental and Radiological Health Sciences Colorado State University Currently Funded Projects Molecular Mechanisms of Radiation-Induced Genomic Instability in Human Cells Technical Abstracts 2003 Workshop: Delayed genomic instability in human lymphoblasts exposed to 137Cs y-rays radiation Schwartz, J.L., Jordan, R., Lenarczyk, M. and Liber, H.L. 2002 Workshop: Molecular Mechanisms of Radiation-Induced Genomic Instability in Human Cells. Liber, H.L. and Schwartz, J.L. Publications Zhang, Y., Zhou, J., Held, K.D., Redmond, R.W., Prise, K.M., and Liber, H.L. (2008). Deficiencies of double-strand break repair factors and effects on mutagenesis in directly [gamma]-irradiated and medium-mediated bystander human lymphoblastoid cells. Radiation Research 169(2):197-206.

290

Low Dose Radiation Research Program: Kenneth T. Bogen  

NLE Websites -- All DOE Office Websites (Extended Search)

T. Bogen Lawrence Livermore National Laboratory Technical Abstracts 2002 Workshop: Low-dose dose-response of proliferating human cells exposed to low dose rate g-radiation. Enns,...

291

radiation.p65  

Office of Legacy Management (LM)

5 5 United States Department of Energy This fact sheet explains the potential health hazards associated with the radioactive decay of uranium and other radioactive elements found in ore and mill tailings. Potential Health Hazards of Radiation Man-made sources of radiation, most notably from medical uses and consumer products, contribute to the remaining radiation dose that individuals receive. A few household products, including smoke detectors, micro- wave ovens, and color televisions, emit small amounts of radiation. For most people, the benefits from using such products far outweigh the radiation risks. Radiation Dose Radiation is measured in various units. Individuals who have been exposed to radiation have received a radiation dose. Radiation dose to people is expressed in

292

Radiative heat transfer between dielectric bodies  

E-Print Network (OSTI)

The recent development of a scanning thermal microscope (SThM) has led to measurements of radiative heat transfer between a heated sensor and a cooled sample down to the nanometer range. This allows for comparision of the known theoretical description of radiative heat transfer, which is based on fluctuating electrodynamics, with experiment. The theory itself is a macroscopic theory, which can be expected to break down at distances much smaller than 10-8m. Against this background it seems to be reasonable to revisit the known macroscopic theory of fluctuating electrodynamics and of radiative heat transfer.

Svend-Age Biehs

2011-03-16T23:59:59.000Z

293

Radiation Field Control Manual  

Science Conference Proceedings (OSTI)

The EPRI Radiation Management Program is dedicated to reducing nuclear power plant worker personnel exposure by developing practices and technologies to increase the radiation protection of the worker, and to implement methods to reduce radiation fields. The nuclear power industry has recently implemented the RP2020 Initiative to promote positive radiation protection trends. Control of radiation fields is crucial to one of the initiative goals of reducing exposure. This manual provides the current state ...

2004-12-16T23:59:59.000Z

294

Device for calibrating a radiation detector system  

DOE Patents (OSTI)

A device for testing a radiation detector system that includes at least two arrays of radiation detectors that are movable with respect to each other. The device includes a "shield plate" or shell, and an opposing "source plate" containing a source of ionizing radiation. Guides are attached to the outer surface of the shell for engaging the forward ends of the detectors, thereby reproducibly positioning the detectors with respect to the source and with respect to each other, thereby ensuring that a predetermined portion of the radiation emitted by the source passes through the shell and reaches the detectors. The shell is made of an hydrogenous material having approximately the same radiological attenuation characteristics as composite human tissue. The source represents a human organ such as the lungs, heart, kidneys, heart, liver, spleen, pancreas, thyroid, testes, prostate, or ovaries. The source includes a source of ionizing radiation having a long half-life and an activity that is within the range typically searched for in human subjects.

Mc Fee, Matthew C. (New Ellenton, SC); Kirkham, Tim J. (Beech Island, SC); Johnson, Tippi H. (Aiken, SC)

1994-01-01T23:59:59.000Z

295

Device for calibrating a radiation detector system  

DOE Patents (OSTI)

A device is disclosed for testing a radiation detector system that includes at least two arrays of radiation detectors that are movable with respect to each other. The device includes a ''shield plate'' or shell, and an opposing ''source plate'' containing a source of ionizing radiation. Guides are attached to the outer surface of the shell for engaging the forward ends of the detectors, thereby reproducibly positioning the detectors with respect to the source and with respect to each other, thereby ensuring that a predetermined portion of the radiation emitted by the source passes through the shell and reaches the detectors. The shell is made of an hydrogenous material having approximately the same radiological attenuation characteristics as composite human tissue. The source represents a human organ such as the lungs, heart, kidneys, liver, spleen, pancreas, thyroid, testes, prostate, or ovaries. The source includes a source of ionizing radiation having a long half-life and an activity that is within the range typically searched for in human subjects. 3 figures.

McFee, M.C.; Kirkham, T.J.; Johnson, T.H.

1994-12-27T23:59:59.000Z

296

Interannual Variability of the Tropical Radiation Balance and the Role of Extended Cloud Systems  

Science Conference Proceedings (OSTI)

The tropical radiation balance is investigated on an interannual time scale using a five-year(197983) dataset obtained from the Nimbus-7 Earth Radiation Budget (ERB) experiment. The study emphasizes the separate contributions to interannual ...

Eric A. Smith; Matthew R. Smith

1987-11-01T23:59:59.000Z

297

The Effect of Clouds on the Earth's Solar and Infrared Radiation Budgets  

Science Conference Proceedings (OSTI)

The effect of global cloudiness on the solar and infrared components of the earth's radiation balance is studied in general circulation model experiments. A wintertime simulation is conducted in which the cloud radiative transfer calculations use ...

Gerald F. Herman; Man-Li C. Wu; Winthrop T. Johnson

1980-06-01T23:59:59.000Z

298

Radiative Effects of Airborne Dust on Regional Energy Budgets at the Top of the Atmosphere  

Science Conference Proceedings (OSTI)

The effects of dust on the radiative energy budget at the top of the atmosphere were investigated using model calculations and measurements from the Earth Radiation Budget Experiment (ERBE). Estimates of the dust optical depth were made from ...

Steven A. Ackerman; Hyosang Chung

1992-02-01T23:59:59.000Z

299

Field Comparisons of Direct and Component Measurements of Net Radiation under Clear Skies  

Science Conference Proceedings (OSTI)

Accurate measurements of net radiation are basic to all studies of the surface energy budget. In preparation for an energy budget experiment significant differences were found between direct and component measurement of net radiation, which ...

Claude E. Duchon; Gregory E. Wilk

1994-02-01T23:59:59.000Z

300

Improved Simulation of Clear-Sky Shortwave Radiative Transfer in the CCC-GCM  

Science Conference Proceedings (OSTI)

The disposition of mean July clear-sky solar radiation in the Canadian Climate Centre second-generation general circulation model (CCC-GCMII) was analyzed by comparing top of the atmosphere (TOA) net fluxes with earth radiation budget experiment (...

Howard W. Barker; Zhanqing Li

1995-09-01T23:59:59.000Z

Note: This page contains sample records for the topic "human radiation experiments" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


301

Observational and Theoretical Studies of Solar Radiation in Arctic Stratus Clouds  

Science Conference Proceedings (OSTI)

A series of clouds-radiation experiments was carried out in June 1980 in Arctic stratus clouds occurring over the Beaufort Sea using the NCAR Electra aircraft. This paper is an analysis of the hemispheric radiation fields obtained with Eppley ...

G. F. Herman; J. A. Curry

1984-01-01T23:59:59.000Z

302

Job security and fear: Do these drive our radiation guidelines  

SciTech Connect

This commentary asks why scientists want radiation standard setting at a level well below that at which any health related problem has been observed in a human being. The idea that job security and fear actually may drive radiation standards is presented as a possibility. 3 refs.

Thomas, R.G.

1994-01-01T23:59:59.000Z

303

Reexamination of the Observed Decadal Variability of the Earth Radiation Budget Using Altitude-Corrected ERBE/ERBS Nonscanner WFOV Data  

Science Conference Proceedings (OSTI)

This paper gives an update on the observed decadal variability of the earth radiation budget (ERB) using the latest altitude-corrected Earth Radiation Budget Experiment (ERBE)/Earth Radiation Budget Satellite (ERBS) Nonscanner Wide Field of View (...

Takmeng Wong; Bruce A. Wielicki; Robert B. Lee III; G. Louis Smith; Kathryn A. Bush; Joshua K. Willis

2006-08-01T23:59:59.000Z

304

Deconvolution of Wide Field-of-View Radiometer Measurements of Earth-Emitted Radiation Part II: Analysis of First Year of Nimbus 6 ERB Data  

Science Conference Proceedings (OSTI)

One year of longwave radiation data from July 1975 through June 1976 from the Nimbus 6 satellite Earth Radiation Budget (ERB) experiment is analyzed by representing the longwave radiation field by a spherical harmonic expansion. The data are from ...

T. Dale Bess; Richard N. Green; G. Louis Smith

1981-03-01T23:59:59.000Z

305

BNL NASA Space Radiation Laboratory  

NLE Websites -- All DOE Office Websites (Extended Search)

Purpose: To use beams of heavy ions provided by the Booster accelerator at Brookhaven to study the effects of simulated space radiation on biological and physical systems, with the goal of developing methods and materials to reduce the risk to human beings on prolonged space missions of the effects of ionizing radiation Sponsor: National Aeronautics and Space Administration (NASA) Project cost $34 million over 4 years Operating costs Nearly $8 million per year in 2007 Features * beams of heavy ions extracted from the Booster accelerator with masses and energies similar to the cosmic rays encountered in space: * 1-billion electron volt (GeV)/nucleon iron-56 * 0.3-GeV/nucleon gold-97 * 0.6-GeV/nucleon silicon-28 * 1-GeV/nucleon protons * 1-GeV/nucleon titanium

306

SANE experiment  

SciTech Connect

The Spin Asymmetries of the Nucleon Experiment (SANE) is a measurement of parallel and near-perpendicular double spin asymmetries in an inclusive electron scattering. The main goal of the experiment was to measure A{sub {parallel}} and A{sub 80} and extract the spin asymmetries of the proton A{sub 1}{sup p}, A{sub 2}{sup p} and spin structure functions g{sub 1}{sup p} and g{sub 2}{sup p}. Using the Thomas Jefferson National Accelerator Facility's polarized electron beam and the University of Virginia's polarized frozen ammonia ({sup 14}NH{sub 3}) target in Hall C, the experiment ran in 2009, collecting data in a Q{sup 2} region from 2.5 to 6.5 GeV{sup 2} and between Bjorken x of 0.3 to 0.8. Particle detection was accomplished using the Big Electron Telescope Array (BETA), a novel non-magnetic detector. This talk will address the progress of the analysis designed to extract the proton spin asymmetries and structure functions. Preliminary results will be presented.

H. Baghdasaryan, SANE Collaboration

2012-04-01T23:59:59.000Z

307

radiation.cdr  

Office of Legacy Management (LM)

Radiation-It's a Fact of Life Radiation-It's a Fact of Life It has been with us since the beginning of time. Everyone who has ever walked on this planet has been exposed to radiation. For the most part, nature is the largest source of exposure. It's in the air we breathe, the ground we walk on, and even the food we eat. The radiation we receive from all natural and some man-made sources is called "background radiation." The millirem (mrem) is a unit used for measuring radiation received by a person. The total average background for radiation received by people living in the United States is 360 millirem per year (mrem/yr), of which 300 mrem/yr is from natural sources, and 60 mrem/yr is man-made. Cosmic Radiation from the sun and stars Internal Radiation from naturally radioactive

308

Reactor Internals Segmentation Experience Report  

Science Conference Proceedings (OSTI)

Several U.S. nuclear power plants entered decommissioning in the 1990's. Based on current information, the next group of plants will not begin this process for nearly a decade. This report provides detailed information on projects involving the segmentation of the Reactor Vessel Internal Subassemblies conducted at a number of plants undergoing decommissioning. Utilities have found this task very challenging from both a technological and radiation exposure perspective. This report documents the experience...

2007-07-10T23:59:59.000Z

309

Low Dose Radiation Program: Links - General Radiation Information  

NLE Websites -- All DOE Office Websites (Extended Search)

General Radiation Information Answers to Questions about Radiation Dose Ranges Charts - tables showing radiation dose ranges from radio diagnostics to cancer radiotherapy....

310

Low Dose Radiation Program: Links - Websites about Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Websites About Radiation The ABC's of Nuclear Science A Teacher's Guide To The Nuclear Science Wall Chart Answers to Questions about Radiation and You Background Radiation:...

311

Particles and People: Aerosol Movement Into and Around the Human Body  

NLE Websites -- All DOE Office Websites (Extended Search)

Particles and People: Aerosol Movement Into and Around the Human Body Particles and People: Aerosol Movement Into and Around the Human Body Speaker(s): Miriam Byrne Date: April 14, 2006 - 12:00pm Location: Bldg. 90 Miriam Byrne is a participating guest in the Airflow and Pollutant Transport Group at LBL. She is an academic member of staff in the Physics Department at the National University of Galway, Ireland. Her research interests, primarily funded by European Commission radiation protection programs, focus on the mechanisms of aerosol transport to and from human body surfaces. Over the last ten years, she has been involved in tracer aerosol experiments to determine rates of particle deposition and resuspension from skin, hair and clothing, as well as studying particle transport into skin pores and hair follicles, and contact transfer from

312

Plutonium radiation surrogate  

DOE Patents (OSTI)

A self-contained source of gamma-ray and neutron radiation suitable for use as a radiation surrogate for weapons-grade plutonium is described. The source generates a radiation spectrum similar to that of weapons-grade plutonium at 5% energy resolution between 59 and 2614 keV, but contains no special nuclear material and emits little .alpha.-particle radiation. The weapons-grade plutonium radiation surrogate also emits neutrons having fluxes commensurate with the gamma-radiation intensities employed.

Frank, Michael I. (Dublin, CA)

2010-02-02T23:59:59.000Z

313

Low Dose Radiation Research Program: William F. Morgan  

NLE Websites -- All DOE Office Websites (Extended Search)

William F. Morgan William F. Morgan Pacific Northwest National Laboratory PO Box 999 Richland, Washington About this Project Projects Using a Low LET Electron Microbeam to Investigate Non-Targeted Effects of Low Dose Radiation. Optimizing the Scientific, Regulatory, and Societal Impact of the DOE Low Dose Radiation Research Program A Mechanistic Study of the Radiation Quality Dependence of Bystander Effects in Human Cells. Genetic Factors Affecting Susceptibility to Low-Dose Radiation Mechanisms of Adaptive Responses and Genomic Instability Induced by Low Dose/ Low Dose Rate Radiation Technical Abstracts 2006 Workshop: Using a Low-LET Electron Microbeam to Investigate Non-Targeted Effects of Low Dose Radiation Sowa, M.B., Goetz, W., Baulch, J., and Morgan, W.F. Genetic Factors Affecting Susceptibility to Low-Dose Radiation

314

Low Dose Radiation Research Program: Genetic Factors affecting...  

NLE Websites -- All DOE Office Websites (Extended Search)

on the genetic background of the cells examined and NBS cells do not form foci after irradiation. In preliminary experiments using IMR90 human fibroblasts, formation of foci...

315

Tachyons and Gravitational Cherenkov Radiation  

E-Print Network (OSTI)

AND GRAVITATIONAL CHERENKOV RADIATION CHARLES SCHWARTZwould emit gravitational radiation. It is very small.gravitational waves; Cherenkov radiation. In a recent work,

Schwartz, Charles

2011-01-01T23:59:59.000Z

316

Los Alamos Lab: Radiation Protection  

NLE Websites -- All DOE Office Websites (Extended Search)

Advisor Paul Hoover Special Assistant and Issues Management Coordinator Elinor Gwynn Radiation Protection Radiation Protection The Radiation Protection Division supports the...

317

RADIATION SAFETY OFFICE UNIVERSITYOF MARYLAND  

E-Print Network (OSTI)

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 2. RADIATION EXPOSURE CONTROL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 2.2.2. Internal ExposureRADIATION SAFETY OFFICE UNIVERSITYOF MARYLAND RADIATION SAFETY MANUAL UNIVERSITY OF MARYLAND

Rubloff, Gary W.

318

Maryland Radiation Act (Maryland)  

Energy.gov (U.S. Department of Energy (DOE))

The policy of the state is to provide for the constructive use of radiation and control radiation emissions. This legislation authorizes the Department of the Environment to develop comprehensive...

319

WI Radiation Protection  

Energy.gov (U.S. Department of Energy (DOE))

This statute seeks to regulate radioactive materials, to encourage the constructive uses of radiation, and to prohibit and prevent exposure to radiation in amounts which are or may be detrimental...

320

Nonionizing Radiation and HIV  

NLE Websites -- All DOE Office Websites (Extended Search)

Nonionizing Radiation and HIV Name: Flora R Pitchford Location: NA Country: NA Date: NA Question: What are the effects of nonionizing radiation on DNA , RNA or any other cell...

Note: This page contains sample records for the topic "human radiation experiments" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


321

Radiation and Ozone  

Science Conference Proceedings (OSTI)

Radiation is the driving force for the general circulation of the atmosphere and controls the Earth's climate. Ozone is responsible for the warm stratosphere and protects life on Earth from harmful solar ultraviolet radiation. In July 1959, the ...

G. Ohring; R. D. Bojkov; H-J. Bolle; R. D. Hudson; H. Volkert

2009-11-01T23:59:59.000Z

322

Development of Pattern Recognition Software for Tracks of Ionizing Radiation In Medipix2-Based  

E-Print Network (OSTI)

, and area monitors to characterize the general background radiation environment harmful to humansDevelopment of Pattern Recognition Software for Tracks of Ionizing Radiation In Medipix2-Based tool for the automated identification and classification of tracks of ionizing radiation as measured

Vilalta, Ricardo

323

Radiation protection at CERN  

E-Print Network (OSTI)

This paper gives a brief overview of the general principles of radiation protection legislation; explains radiological quantities and units, including some basic facts about radioactivity and the biological effects of radiation; and gives an overview of the classification of radiological areas at CERN, radiation fields at high-energy accelerators, and the radiation monitoring system used at CERN. A short section addresses the ALARA approach used at CERN.

Forkel-Wirth, Doris; Silari, Marco; Streit-Bianchi, Marilena; Theis, Christian; Vincke, Heinz; Vincke, Helmut

2013-01-01T23:59:59.000Z

324

Radiation Dosimetry Data  

Science Conference Proceedings (OSTI)

Radiation Dosimetry Data. Stopping-Power and Range Tables for Electrons, Protons, and Helium Ions. MJ Berger The databases ...

2010-10-05T23:59:59.000Z

325

Radiation Shields Materials  

Science Conference Proceedings (OSTI)

About this Abstract. Meeting, Materials Science & Technology 2009. Symposium, Materials Solutions for the Nuclear Renaissance. Presentation Title, Radiation...

326

In situ measurement of lattice strain using synchrotron radiation and a conical slit system.  

E-Print Network (OSTI)

??An experiment utilizing synchrotron radiation to measure lattice strain components from an aluminum-lithium sample during tensile loading is presented in detail. The conical slit system (more)

Obstalecki, Mark

2011-01-01T23:59:59.000Z

327

IMPRINTED GENES & TRANSPOSITIONS: EPIGENOMIC TARGETS FOR LOW DOSE RADIATION EFFECTS  

Science Conference Proceedings (OSTI)

The overall hypothesis of this grant application is that low dose ionizing radiation (LDIR) elicits adaptive responses in part by causing heritable DNA methylation changes in the epigenome. This novel postulate was tested by determining if the level of DNA methylation at the Agouti viable yellow (A{sup vy}) metastable locus is altered, in a dose-dependent manner, by low dose radiation exposure (radiation hormesis, bringing into question the assumption that every dose of radiation is harmful. Our findings not only have significant implications concerning the mechanism of hormesis, but they also emphasize the potential importance of this phenomenon in determining human risk at low radiation doses. Since the epigenetic regulation of genes varies markedly between species, the effect of LDIR on other epigenetically labile genes (e.g. imprinted genes) in animals and humans needs to be defined.

Randy Jirtle

2012-10-11T23:59:59.000Z

328

Surface Energy and Radiation Balance Systems: General Description and Improvements  

Science Conference Proceedings (OSTI)

Surface evaluation of sensible and latent heat flux densities and the components of the radiation balance were desired for various vegetative surfaces during the ASCOT84 experiment to compare with modeled results and to relate these values to ...

Leo J. Fritschen; James R. Simpson

1989-07-01T23:59:59.000Z

329

Radiation Energy Budget Studies Using Collocated AVHRR and ERBE Observations  

Science Conference Proceedings (OSTI)

Changes in the energy balance at the top of the atmosphere are specified as a function of atmospheric and surface properties using observations from the Advanced Very High Resolution Radiometer (AVURR) and the Earth Radiation budget Experiment (...

Steven A. Ackerman; Toshiro Inoue

1994-03-01T23:59:59.000Z

330

A Simulated Climatology of Spectrally Decomposed Atmospheric Infrared Radiation  

Science Conference Proceedings (OSTI)

A simulation experiment is conducted to inquire into the mean climate state and likely trends in atmospheric infrared radiation spectra. Upwelling and downwelling spectra at five vertical levels from the surface to the top of the atmosphere (TOA) ...

Yi Huang

2013-03-01T23:59:59.000Z

331

Low Dose Radiation Research Program: Mechanistic Modeling of...  

NLE Websites -- All DOE Office Websites (Extended Search)

Laboratory Why This Project? Cells that are directly exposed to low doses of ionizing radiation may experience DNA damage. Cells which happen to be in the vicinity of the exposed...

332

An Analytic Longwave Radiation Formula for Liquid Layer Clouds  

Science Conference Proceedings (OSTI)

Many Global Energy and Water Cycle Experiment (GEWEX) Cloud System Study (GCSS) intercomparisons of boundary layer clouds have used a convenient but idealized longwave radiation formula for clouds in their large-eddy simulations (LESs). Under ...

Vincent E. Larson; Kurt E. Kotenberg; Norman B. Wood

2007-02-01T23:59:59.000Z

333

A Surface Solar Radiation Model for Cloudy Atmospheres  

Science Conference Proceedings (OSTI)

A numerical solar radiation model based on standard meteorological data was revised for clouds using data from the GARP Atlantic Tropical Experiment (GATE). Climatic-mean transmittance functions were revised for low and convective clouds ...

Marshall A. Atwater; John T. Ball

1981-04-01T23:59:59.000Z

334

Rainfall and Radiative Heating Rates from TOGA COARE Atmospheric Budgets  

Science Conference Proceedings (OSTI)

Atmospheric heat and moisture budgets are used to determine rainfall and radiative heating rates over the western Pacific warm pool during the Tropical Ocean Global Atmosphere Coupled OceanAtmosphere Response Experiment (TOGA COARE). Results are ...

Richard H. Johnson; Paul E. Ciesielski

2000-05-01T23:59:59.000Z

335

Radiative Heating and Cooling Rates in the Middle Atmosphere  

Science Conference Proceedings (OSTI)

One of the limitations to the accurate calculation of radiative heating and cooling rates in the stratosphere and mesosphere has been the lack of accurate data on the atmospheric temperature and composition. Data from the LIMS experiment on ...

John C. Gille; Lawrence V. Lyjak

1986-10-01T23:59:59.000Z

336

Radiation Effects in Ceramic Oxide and Novel LWR Fuels  

Science Conference Proceedings (OSTI)

Jul 31, 2011 ... TMS/ASM: Nuclear Materials Committee ... of radiation response of nuclear fuel through experiment, theory and computational multi-scale modeling. ... test reactors and commercial nuclear power reactors are all of interest.

337

Human Health  

NLE Websites -- All DOE Office Websites (Extended Search)

Human Health Print E-mail Climate change can have a number of direct and indirect effects on human health. For example, rising temperatures can contribute to the number of deaths...

338

Polarized photons in radiative muon capture  

E-Print Network (OSTI)

We discuss the measurement of polarized photons arising from radiative muon capture. The spectrum of left circularly polarized photons or equivalently the circular polarization of the photons emitted in radiative muon capture on hydrogen is quite sensitive to the strength of the induced pseudoscalar coupling constant $g_P$. A measurement of either of these quantities, although very difficult, might be sufficient to resolve the present puzzle resulting from the disagreement between the theoretical prediction for $g_P$ and the results of a recent experiment. This sensitivity results from the absence of left-handed radiation from the muon line and from the fact that the leading parts of the radiation from the hadronic lines, as determined from the chiral power counting rules of heavy-baryon chiral perturbation theory, all contain pion poles.

Shung-ichi Ando; Harold W. Fearing; Dong-Pil Min

2001-04-25T23:59:59.000Z

339

Radiative Forcing of Simulated Tropical Cloud Clusters  

Science Conference Proceedings (OSTI)

A number of field experiments and subsequent studies in the 1970s and 1980s have led to the belief that radiative processes play a more significant role in the evolution of tropical mesoscale convective systems (MCSS) than was once thought. In ...

Rosemary Auld Miller; William M. Frank

1993-02-01T23:59:59.000Z

340

New Paradigm for Macromolecular Crystallography Experiments at SSRL: Automated Crystal Screening And Remote Data Collection  

Science Conference Proceedings (OSTI)

Complete automation of the macromolecular crystallography experiment has been achieved at Stanford Synchrotron Radiation Lightsource (SSRL) through the combination of robust mechanized experimental hardware and a flexible control system with an intuitive user interface. These highly reliable systems have enabled crystallography experiments to be carried out from the researchers' home institutions and other remote locations while retaining complete control over even the most challenging systems. A breakthrough component of the system, the Stanford Auto-Mounter (SAM), has enabled the efficient mounting of cryocooled samples without human intervention. Taking advantage of this automation, researchers have successfully screened more than 200 000 samples to select the crystals with the best diffraction quality for data collection as well as to determine optimal crystallization and cryocooling conditions. These systems, which have been deployed on all SSRL macromolecular crystallography beamlines and several beamlines worldwide, are used by more than 80 research groups in remote locations, establishing a new paradigm for macromolecular crystallography experimentation.

Soltis, S.M.; Cohen, A.E.; Deacon, A.; Eriksson, T.; Gonzalez, A.; McPhillips, S.; Chui, H.; Dunten, P.; Hollenbeck, M.; Mathews, I.; Miller, M.; Moorhead, P.; Phizackerley, R.P.; Smith, C.; Song, J.; Bedem, H.van dem; Ellis, P.; Kuhn, P.; McPhillips, T.; Sauter, N.; Sharp, K.

2009-05-26T23:59:59.000Z

Note: This page contains sample records for the topic "human radiation experiments" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


341

ATLAS APPROVED EXPERIMENTS  

NLE Websites -- All DOE Office Websites (Extended Search)

8MAY98 8MAY98 Exp # Spokesperson Experiment Title Days 433-9 Miller Ion Irradiations of Anisotropic High-Tc Superconductors: Probing Dynamics of Magnetic Vortices 2 651-2 Paul Accelerator-Mass-Spectrometry Measurements of Natural 236U Concentrations with the ECR-ATLAS System 4 667-2 Janssens Unsafe Coulex of the 238,239Pu Nuclei 4 669-2 Carpenter Excited States Associated with Different Shapes in 178Hg and Neighboring Odd-A Nuclei 4 673-2 Lister A Study of Radiative Decay from High Lying States in 24Mg 5 689-2 Freeman Spectroscopy of Odd Tin Isotopes Approaching 100Sn 5 693-2 Reiter Structure and Formation Mechanism of Heavy Elements - Request for additional beam time for Experiment 693 - 6 706 Kwok Heavy-Ion Lithography on High Temperature Superconductors 2 708 Yu In-Beam Spectroscopy Study of the Proton Emitter 109I with Recoil-Decay Tagging Technique

342

Radioactivity and Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Radioactivity and Radiation Radioactivity and Radiation Uranium and Its Compounds line line What is Uranium? Chemical Forms of Uranium Properties of Uranium Compounds Radioactivity and Radiation Uranium Health Effects Radioactivity and Radiation Discussion of radioactivity and radiation, uranium and radioactivity, radiological health risks of uranium isotopes and decay products. Radioactivity Radioactivity is the term used to describe the natural process by which some atoms spontaneously disintegrate, emitting both particles and energy as they transform into different, more stable atoms. This process, also called radioactive decay, occurs because unstable isotopes tend to transform into a more stable state. Radioactivity is measured in terms of disintegrations, or decays, per unit time. Common units of radioactivity

343

PERSONAL RADIATION MONITOR  

DOE Patents (OSTI)

A transistorized, fountain pen type radiation monitor to be worn on the person is described. Radiation produces both light flashes in a small bulb and an audible warning tone, the frequency of both the tone and light flashes being proportional to radiation intensity. The device is powered by a battery and a blocking oscillator step-up power supply The oscillator frequency- is regulated to be proportional to the radiation intensity, to provide adequate power in high radiation fields, yet minimize battery drain at low operating intensities. (AEC)

Dilworth, R.H.; Borkowski, C.J.

1961-12-26T23:59:59.000Z

344

Radiation detection system  

DOE Patents (OSTI)

A radiation detection system which utilizes the generation of Cerenkov light in and the transmission of that light longitudinally through fiber optic wave guides in order to transmit intelligence relating to the radiation to a remote location. The wave guides are aligned with respect to charged particle radiation so that the Cerenkov light, which is generated at an angle to the radiation, is accepted by the fiber for transmission therethrough. The Cerenkov radiation is detected, recorded, and analyzed at the other end of the fiber.

Nelson, Melvin A. (Santa Barbara, CA); Davies, Terence J. (Santa Barbara, CA); Morton, III, John R. (Livermore, CA)

1976-01-01T23:59:59.000Z

345

Vertical Profiles of Aerosol and Radiation and the Influence of a Temperature Inversion: Measurements and Radiative Transfer Calculations  

Science Conference Proceedings (OSTI)

The results of an airborne experiment performed near Mnchengladbach (Germany) in November 1993 are reported. Besides meteorological data, vertical profiles of aerosol properties (number concentration, size distribution) and radiation (...

M. Wendisch; S. Mertes; A. Ruggaber; T. Nakajima

1996-10-01T23:59:59.000Z

346

Continuous Emission of A Radiation Quantum  

E-Print Network (OSTI)

It is in accordance with such experiments as single photon self-interference that a photon, conveying one radiation energy quantum "$ h \\times$ frequency", is spatially extensive and stretches an electromagnetic wave train. A wave train, hence an energy quantum, can only be emitted by its source gradually. In both the two processes the wave and "particle" attributes of the radiation field are simultaneously prominent, where an overall satisfactory theory has been lacking. This paper presents a first principles treatment, in a unified framework of the classical and quantum mechanics, of the latter process, the emission of a single radiation quantum based on the dynamics of the radiation-emitting source, a charged oscillator which is itself extensive across its confining potential well. During the emission of one single radiation quantum, the extensive charged oscillator undergoes a continuous radiation damping and is non-stationary. This process is in this work treated using a quasi stationary approach, whereby the classical equation of motion, which directly facilitates the correspondence principle for a particle oscillator, and the quantum wave equation are established for each sufficiently brief time interval. As an inevitable consequence of the division of the total time for emitting one single quantum, a fractional Planck constant $h$ is introduced. The solutions to the two simultaneous equations yield for the charged oscillator a continuously exponentially decaying Hamiltonian that is at the same time quantised with respect to the fractional-$h$ at any instant of time; and the radiation wave field emitted over time stretches a wave train of finite length. The total system of the source and radiation field maintains at any time (integer $n$ times) one whole energy quantum, $h \\times$ frequency, in complete accordance with the notion of quantum mechanics and experiment.

J. X. Zheng-Johansson

2013-11-29T23:59:59.000Z

347

TERSat: Trapped Energetic Radiation Satellite  

E-Print Network (OSTI)

Radiation damage caused by interactions with high-energy particles in the Van Allen Radiation Belts is a leading

Clements, Emily B.

2012-01-01T23:59:59.000Z

348

NIST Optical Radiation Staff Directory  

Science Conference Proceedings (OSTI)

Optical Radiation Staff Directory. Staff. Name, Position, Office Phone. ... Contact. Optical Radiation Group Eric Shirley, Group Leader. ...

2013-08-02T23:59:59.000Z

349

NVLAP Ionizing Radiation Dosimetry LAP  

Science Conference Proceedings (OSTI)

Ionizing Radiation Dosimetry LAP. ... This site has been established for applicants to the accreditation program for ionizing radiation dosimetry. ...

2013-07-23T23:59:59.000Z

350

Radiation and Biomolecular Physics Division  

Science Conference Proceedings (OSTI)

... Welcome. The Radiation and Biomolecular Physics Division is a division ... disseminate the national standards for ionizing radiations and radioactivity ...

2012-02-08T23:59:59.000Z

351

NIST Radiation Thermometry Short Course  

Science Conference Proceedings (OSTI)

NIST Radiation Thermometry Short Course. ... 2012 NIST Radiation Thermometry Short Course October 15-19, 2012 NIST Gaithersburg, Maryland. ...

2012-10-01T23:59:59.000Z

352

NIST Ionizing Radiation Division - 2001  

Science Conference Proceedings (OSTI)

... The Ionizing Radiation Division of the Physics Laboratory supports the ... meaningful, and compatible measurements of ionizing radiations (x rays ...

353

ORISE: Graduate Student Research Experiences - Augusto Tentori  

NLE Websites -- All DOE Office Websites (Extended Search)

Augusto Tentori Augusto Tentori Student's expertise in microfluidics helps develop prototype device for human radiation exposure detection If the unthinkable happens, time is of the essence in a potential mass population radiological event, where thousands of people would be exposed to radiation and their survival could hinge on prompt medical diagnosis and treatment. Augusto Tentori Augusto Tentori, a participant in the U.S. Department of Homeland Security's Scholarship and Fellowship Program (administered for DHS by the Oak Ridge Institute for Science and Education), uses microfluidic technology to analyze blood samples for evidence and calculation of radiation exposure dose-a field known as "radiation biodosimetry." Photo courtesy of Christopher Phaneuf. Click image to enlarge.

354

Los Alamos and NNSS team to resume critical experiments at new...  

NLE Websites -- All DOE Office Websites (Extended Search)

radiation detection instruments and providing hands-on training for criticality safety engineers and nuclear-material handlers. These experiments address issues including...

355

Solar radiation model validation  

Science Conference Proceedings (OSTI)

Several mathematical models have been developed within the past few years which estimate the solar radiation from other weather variables. Some of these models have been used to generate data bases which are extensively used in the design and analysis of solar system. Three of these solar radiation models have been used in developing the Augmented SOLMET Solar Data Tapes for the 26 SOLMET sites and the 222 ERSATZ Solar Data Tapes. One of the models, a theoretical one, predicts the solar noon radiation for clear sky conditions from the optical air mass, precipitable water vapor and turbidity variables. A second model, an empirical one, predicts the hourly total horizontal radiation from meteorological variables. And, a third model, also an empirical one, predicts the hourly direct normal radiation from the hourly total horizontal radiation. A study of the accuracy of these three solar radiation models is reported here. To assess the accuracy of these models, data were obtained from several US National Weather Service Stations and other sources, used the models to estimate the solar-radiation, and then compared the modeled radiation values with observed radiation values. The results of these comparisons and conclusions regarding the accuracy of the models are presented.

Hall, I.J.; Prairie, R.R.; Anderson, H.E.; Boes, E.C.

1980-10-01T23:59:59.000Z

356

RADIATION SAFETY MANUAL  

E-Print Network (OSTI)

RADIATION SAFETY is the responsibility of all faculty, staff and students who are directly or indirectly involved in the use of radioisotopes or radiation-producing machines. In July 1963, the State of Texas granted The University of Texas at Austin a broad radioactive materials license for research, development and instruction. While this means a minimum of controls by the state, it requires that The University establish and pursue an effective Radiation Safety Program. The Radiation Safety Committee is responsible for The University's radiation control program outlined in this manual. The use of radiation in a university, where a large number of people may be unaware of their exposure to radiation hazards, makes strict adherence to procedures established by federal and state authorities of paramount importance for the protection of The University and the safety of its faculty, staff and students. It is the responsibility of all faculty, staff and students involved in radiation work to familiarize themselves thoroughly with The University's radiation control program and to comply with its requirements and all applicable federal and state regulations. I hope you will always keep in mind that radiation safety depends on a continuous awareness of potential hazards and on the acceptance

unknown authors

2005-01-01T23:59:59.000Z

357

The Response of a Spectral General Circulation Model to Refinements in Radiative Processes  

Science Conference Proceedings (OSTI)

We present here results and analyses of a series of numerical experiments performed with a spectral general circulation model (GCM). The purpose of the GCM experiments is to examine the role of radiation/cloud processes in the general circulation ...

V. Ramanathan; Eric J. Pitcher; Robert C. Malone; Maurice L. Blackmon

1983-03-01T23:59:59.000Z

358

Applying augmented reality to consumer garment try-on experience  

Science Conference Proceedings (OSTI)

Experience in this paper refers to the sentimental episode of consumers through service. Through experience or service, consumers can reach their internal sentiment. In terms of the general garment try-on, if consumers cannot experience the practical ... Keywords: augmented reality, consumer, experience, graphical user interface, human-machine interactive system, usability engineering methods

Alfred Chen; Chen-Yuan Kao; Ying-Hsiu Chen; Wen-Cheng Wang

2011-01-01T23:59:59.000Z

359

The Radiation Monitoring System for the LHCb Inner Tracker  

E-Print Network (OSTI)

The performance of the LHCb Radiation Monitoring System (RMS) designed to monitor radiation load on the Inner Trackersilicon micro-strip detectors is presented. The RMS comprises Metal Foil Detectors read-out by sensitive Charge Integrators. MFD is a radiation hard detector operating at high charged particle ?uxes. RMS is used to monitor radiation load as well as relative luminosity of the LHCb experiment. The results obtained by the RMS during LHC operation in 20102011 are compared to the Monte-Carlo simulation.

Okhrimenko, O; Pugatch, V; Alessio, F; Corti, G

2011-01-01T23:59:59.000Z

360

Comparison of Radiation Budget at the TOA and Surface in the Antarctic from ERBE and Ground Surface Measurements  

Science Conference Proceedings (OSTI)

Radiative fluxes at the top of the atmosphere (TOA) and the surface were compared at two Antarctic stations, Syowa and the South Pole, using Earth Radiation Budget Experiment (ERBE) data and surface observations. Fluxes at both sites were plotted ...

Takashi Yamanouchi; Thomas P. Charlock

1995-12-01T23:59:59.000Z

Note: This page contains sample records for the topic "human radiation experiments" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


361

Atmospheric Radiation Measurement Program  

NLE Websites -- All DOE Office Websites (Extended Search)

3 3 ARM 2003 Tom Ackerman Chief Scientist Tom Ackerman Chief Scientist ARM ARM Atmospheric Radiation Measurement Atmospheric Radiation Measurement WARNING! WARNING! Today is April 1 But that has NO bearing on this message Today is April 1 But that has NO bearing on this message ARM ARM Atmospheric Radiation Measurement Atmospheric Radiation Measurement Two Topics Two Topics * Status of ARM (quick overview) * Science plan - ARM in the next 5 years * Status of ARM (quick overview) * Science plan - ARM in the next 5 years ARM ARM Atmospheric Radiation Measurement Atmospheric Radiation Measurement ARM Status - Science ARM Status - Science * Steadily increasing productivity - Poster session - over 220 posters (may need to do something about submissions next year) - Peer-reviewed articles: 2.5 to 3 per year per

362

RADIATION WAVE DETECTION  

DOE Patents (OSTI)

Radiation waves can be detected by simultaneously measuring radiation- wave intensities at a plurality of space-distributed points and producing therefrom a plot of the wave intensity as a function of time. To this end. a detector system is provided which includes a plurality of nuclear radiation intensity detectors spaced at equal radial increments of distance from a source of nuclear radiation. Means are provided to simultaneously sensitize the detectors at the instant a wave of radiation traverses their positions. the detectors producing electrical pulses indicative of wave intensity. The system further includes means for delaying the pulses from the detectors by amounts proportional to the distance of the detectors from the source to provide an indication of radiation-wave intensity as a function of time.

Wouters, L.F.

1960-08-30T23:59:59.000Z

363

Radiation coloration resistant glass  

SciTech Connect

A radiation coloration resistant glass is disclosed which is used in a radiation environment sufficient to cause coloration in most forms of glass. The coloration resistant glass includes higher proportions by weight of water and has been found to be extremely resistant to color change when exposed to such radiation levels. The coloration resistant glass is free of cerium oxide and has more than about 0.5% by weight water content. Even when exposed to gamma radiation of more than 10.sup.7 rad, the coloration resistant glass does not lose transparency.

Tomozawa, Minoru (Troy, NY); Watson, E. Bruce (Troy, NY); Acocella, John (Troy, NY)

1986-01-01T23:59:59.000Z

364

Radiation Shielding Applications  

NLE Websites -- All DOE Office Websites (Extended Search)

Shielding Radiation Shielding Applications Heavy concrete is standard concrete in which conventional aggregate (typically gravel) is replaced with aggregate composed of a dense...

365

Radiation Hazards Program (Minnesota)  

Energy.gov (U.S. Department of Energy (DOE))

These regulations, promulgated by the Department of Health, set allowable radiation standards and mitigation practices, as well as procedures for the transportation of hazardous material.

366

Atomic Radiation (Illinois)  

Energy.gov (U.S. Department of Energy (DOE))

This article states permissible levels of radiation in unrestricted areas, environmental standards for uranium fuel cycle and information about notification of incidents.

367

Quick Reference Information - Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Gamma and x-rays are photons. Protons: Positively charged elementary particles found in atomic nuclei. Radiation: The propagation of energy through space, or some other medium,...

368

Synchrotron Radiation Effects  

NLE Websites -- All DOE Office Websites (Extended Search)

Synchrotron Radiation Effects in the IR Solenoid Flux Excluder Peter Tenenbaum LCC-Note-0007 Draft 23-September-1998 Abstract We examine the emittance dilution due to synchrotron...

369

Living with radiation  

SciTech Connect

The authors present an account of the hopes and fears associated with ionizing radiation, extending from nuclear energy and medical radiation to nuclear weapons. They argue that a justified fear of nuclear weapons has led to a widespread, unjustified, and unreasoning fear of the beneficial applications of radiation. Although these two aspects of atomic energy are tied together-they both involve the nucleus of the atom and its radioactive rays-a deep misunderstanding of this relationship by the general public has evolved since the time of the atomic bombing of Hiroshima and Nagasaki. The authors' aim is to place the beneficial applications of nuclear radiation in perspective.

Wagner, H.N. Jr. (Johns Hopkins Medical Institutions, Baltimore, MD (USA). Div. of Nuclear Medicine); Ketchum, L.E. (Proclinica, Inc., New York, NY (US))

1989-01-01T23:59:59.000Z

370

Carbonaceous Aerosols and Radiative...  

NLE Websites -- All DOE Office Websites (Extended Search)

Aerosols and Radiative Effects Study Science Objective This field campaign is designed to increase scientific knowledge about the evolution of black carbon, primary organic...

371

Radiation Hard Silicon Detectors For the SLHC  

E-Print Network (OSTI)

While the CERN Large Hadron Collider (LHC) will start taking data this year, scenarios for a machine upgrade to achieve a much higher luminosity are being developed. In the current planning, it is foreseen to incrase the luminosity of the LHC at CERN around 2016. As radiation damage scales with integrated luminosity, the particle physics experiments will need to be equipped with a new generation of radiation hard detectors. This article reports on the status of the R&D projects on radiation hard silicon strips detectors for particle physics, linked to the Large Hadron Collider Upgrader, Super-LHC (SLHC) of the ATLAS micro-stip detector. The primary focus of this report is on measuring the radiation hardness of the silicon materials and detectors under study. This involves designing silicon detectors, irradiating them to the SLHC radiation levels and studying their performance as particle detectors. The most promising silicon detector for the different radiation levels in the different regions of the ATLAS...

The ATLAS collaboration

2009-01-01T23:59:59.000Z

372

Third conference on radiation protection and dosimetry  

SciTech Connect

This conference has been designed with the objectives of promoting communication among applied, research, regulatory, and standards personnel involved in radiation protection and providing them with sufficient information to evaluate their programs. To partly fulfill these objectives, a technical program consisting of more than 75 invited and contributed oral presentations encompassing all aspects of radiation protection has been prepared. General topics include external dosimetry, internal dosimetry, instruments, regulations and standards, accreditation and test programs, research advances, and applied program experience. This publication provides a summary of the technical program and a collection of abstracts of the oral presentations.

Not Available

1991-01-01T23:59:59.000Z

373

Modelling magnetically dominated and radiatively cooling jets  

E-Print Network (OSTI)

Using 3D-MHD Eulerian-grid numerical simulations, we study the formation and evolution of rising magnetic towers propagating into an ambient medium. The towers are generated from a localized injection of pure magnetic energy. No rotation is imposed on the plasma. We compare the evolution of a radiatively cooling tower with an adiabatic one, and find that both bend due to pinch instabilities. Collimation is stronger in the radiative cooling case; the adiabatic tower tends to expand radially. Structural similarities are found between these towers and the millimeter scale magnetic towers produced in laboratory experiments.

Huarte-Espinosa, Martin; Blackman, Eric

2010-01-01T23:59:59.000Z

374

Low-Dose/Dose-Rate Low-LET Radiation Protects Us from Cancer  

NLE Websites -- All DOE Office Websites (Extended Search)

Dose/Dose-Rate Low-LET Radiation Protects Us from Cancer Dose/Dose-Rate Low-LET Radiation Protects Us from Cancer Bobby R. Scott, Ph.D. and Jennifer D. Di Palma Lovelace Respiratory Research Institute, 2425 Ridgecrest Drive SE Albuquerque, NM 87108 USA Life on earth evolved in a low-level ionizing radiation environment comprised of terrestrial radiation and cosmic rays. Today we all reside in an ionizing radiation environment comprised of both natural background radiation and radiation from human activities (e.g., Chernobyl accident). An evolutionary benefit of the interaction of low-level, low linear-energy-transfer (LET) ionizing radiation with mammalian life forms on earth is adapted protection. Adapted protection involves low-dose/dose-rate, low-LET radiation induced high-fidelity DNA repair in cooperation with normal apoptosis (presumed p53

375

Turkey vs. human digestion  

NLE Websites -- All DOE Office Websites (Extended Search)

Turkey vs. human digestion Turkey vs. human digestion Name: wallyb Location: N/A Country: N/A Date: N/A Question: How is the digestive system of turkeys different from that of humans? Replies: Hmmm.. been a while since I had sophomore biology, so I can't completely answer this one, but I can say a few things. One, since turkeys are birds, and birds as a general rule have not had teeth for several million years at least, the turkey needs a way to mash up its food -- thus, the crop, which is essentially like another stomach: the turkey (and many other birds, for that matter) swallows small stones which serve in lieu of teeth, mashing up food via muscular action in the crop, from whence the "chewed" food moves on into the rest of the digestive tract. As for any other differences, I'll have to leave that to someone else with more ornithological experience...

376

Radiation monitoring system for the environment and safety project  

E-Print Network (OSTI)

The project RAMSES (Radiation Monitoring System for the Environment and Safety) will provide LHC with a state of the art radiation monitoring and alarm system. RAMSES will survey the LHC accelerator, the LHC experimental areas and the environment of the LHC. The TIS (Technical Inspection and Safety) division will exploit this system to assess radiation risks and to control the releases of radioactivity. In addition, it will be integrated into the control rooms of the LHC accelerator and the LHC experiments. Obviously, RAMSES will already take into account CERN wide needs to renew the radiation monitoring system around the other CERN facilities. The requirements of the system are derived from CERN's own safety standards (CERN's Radiation Protection Manual, SAPOCO), from those of the CERN's two host states and from European standards. The mandate of the project team covers the system specification, prototyping, tendering, installation and integration of radiation monitors and industrial control equipment for sa...

Forkel-Wirth, Doris; Scibile, L; Segura, G; Vojtyla, P; CERN. Geneva. ST Division

2002-01-01T23:59:59.000Z

377

Radiation and Chemical Risk Management [EVS Program Area]  

NLE Websites -- All DOE Office Websites (Extended Search)

Radiation and Chemical Risk Management Radiation and Chemical Risk Management EVS helps meet the challenge of protecting human health and the environment through the management of risk associated with radiation and chemicals in the environment. Protecting human health, welfare, and the environment in a world affected by energy production and technology is a global challenge. EVS helps to meet this challenge through research and analysis on the management of risk associated with radiation and chemicals in the environment. To improve the management of risk associated with nuclear and chemical materials and wastes at contaminated sites, we develop information and tools that support decision making related to health, safety, environmental, economic, and social-cultural concerns. Nuclear Materials and Waste Disposition

378

Solar radiation modelling  

Science Conference Proceedings (OSTI)

The Sun is the main energy source of the life on the Earth. Thus, solar radiation energy data and models are important for many areas of research and applications. Many parameters influence the amount of solar energy at a particular standing point of ... Keywords: Digital elevation model, Energy of quasiglobal radiation, Meteorology, Shadows, Virtual Sun motion

Klemen Zakek; Toma Podobnikar; Kritof Otir

2005-03-01T23:59:59.000Z

379

Electromagnetic radiation detector  

DOE Patents (OSTI)

An electromagnetic radiation detector including a collimating window, a cathode member having a photoelectric emissive material surface angularly disposed to said window whereby radiation is impinged thereon at acute angles, an anode, separated from the cathode member by an evacuated space, for collecting photoelectrons emitted from the emissive cathode surface, and a negatively biased, high transmissive grid disposed between the cathode member and anode.

Benson, Jay L. (Albuquerque, NM); Hansen, Gordon J. (Albuquerque, NM)

1976-01-01T23:59:59.000Z

380

Radiation detection system  

SciTech Connect

A radiation detection system including a radiation-to-light converter and fiber optic wave guides to transmit the light to a remote location for processing. The system utilizes fluors particularly developed for use with optical fibers emitting at wavelengths greater than about 500 nm and having decay times less than about 10 ns.

Franks, Larry A. (Santa Barbara, CA); Lutz, Stephen S. (Santa Barbara, CA); Lyons, Peter B. (Los Alamos, NM)

1981-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "human radiation experiments" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


381

Requirements for the GCFR plenum streaming experiment  

SciTech Connect

This report gives the experiment objectives and generic descriptions of experimental configurations for the gas-cooled fast breeder reactor (GCFR) plenum shield experiment. This report defines four experiment phases. Each phase represents a distinct area of uncertainty in computing radiation transport from the GCFR core to the plenums, through the upper and lower plenum shields, and ultimately to the prestressed concrete reactor vessel (PCRV) liner: (1) the shield heterogeneity phase; (2) the exit shield simulation phase; (3) the plenum streaming phase; and (4) the plenum shield simulation phase.

Perkins, R.G.; Rouse, C.A.; Hamilton, C.J.

1980-09-01T23:59:59.000Z

382

Fundamentals of Radiation Dosimetry  

Science Conference Proceedings (OSTI)

The basic concepts of radiation dosimetry are reviewed on basis of ICRU reports and text books. The radiation field is described with, among others, the particle fluence. Cross sections for indirectly ionizing radiation are defined and indicated is how they are related to the mass energy transfer and mass energy absorption coefficients. Definitions of total and restricted mass stopping powers of directly ionizing radiation are given. The dosimetric quantities, kerma, absorbed dose and exposure together with the relations between them are discussed in depth. Finally it is indicated how the absorbed dose can be measured with a calorimeter by measuring the temperature increase and with an ionisation chamber measuring the charge produced by the ionizing radiation and making use of the Bragg-Gray relation.

Bos, Adrie J. J. [Delft University of Technology, Faculty of Applied Sciences, Mekelweg 15, 2629JB Delft (Netherlands)

2011-05-05T23:59:59.000Z

383

Underwater radiation detector  

DOE Patents (OSTI)

A detector apparatus for differentiating between gamma and neutron radiation is provided. The detector includes a pair of differentially shielded Geiger-Mueller tubes. The first tube is wrapped in silver foil and the second tube is wrapped in lead foil. Both the silver and lead foils allow the passage of gamma rays at a constant rate in a gamma ray only field. When neutrons are present, however, the silver activates and emits beta radiation that is also detected by the silver wrapped Geiger-Mueller tube while the radiation detected by the lead wrapped Geiger-Mueller tube remains constant. The amount of radiation impinging on the separate Geiger-Mueller tubes is then correlated in order to distinguish between the neutron and gamma radiations.

Kruse, Lyle W. (Albuquerque, NM); McKnight, Richard P. (Albuquerque, NM)

1986-01-01T23:59:59.000Z

384

Low Dose Radiation Research Program: Slide Shows  

NLE Websites -- All DOE Office Websites (Extended Search)

Dose Health Effects of Radiation Health Effects of Radiation Adaptive Response to Low Dose Radiation PDF Background Radiation PDF Bystander Effects PDF Dirty Bombs PDF DNA Damage...

385

Low Dose Radiation Program: Links - Organizations Funding Radiation...  

NLE Websites -- All DOE Office Websites (Extended Search)

Funding Radiation Research Australian Radiation Protection and Nuclear Safety Agency Canadian Nuclear Safety Commission Centers for Medical Countermeasures Against Radiological and...

386

National Solar Radiation Data Base

The National Solar Radiation...  

Open Energy Info (EERE)

National Solar Radiation Data Base (NSRDB) is the most comprehensive collection of solar data freely available. The 1991 - 2005 NSRDB contains hourly solar radiation (including...

387

Radiation Damage in Polarized Ammonia Solids  

E-Print Network (OSTI)

Solid NH3 and ND3 provide a highly polarizable, radiation resistant source of polarized protons and deuterons and have been used extensively in high luminosity experiments investigating the spin structure of the nucleon. Over the past twenty years, the UVA polarized target group has been instrumental in producing and polarizing much of the material used in these studies, and many practical considerations have been learned in this time. In this discussion, we analyze the polarization performance of the solid ammonia targets used during the recent JLab Eg4 run. Topics include the rate of polarization decay with accumulated charge, the annealing procedure for radiation damaged targets to recover polarization, and the radiation induced change in optimum microwave frequency used to polarize the sample. We also discuss the success we have had in implementing frequency modulation of the polarizing microwave frequency.

K. Slifer

2007-11-28T23:59:59.000Z

388

The Properties of Undulator Radiation  

E-Print Network (OSTI)

of a Dedicated Synchrotron Radiation Facility," IEEE Trans.1983), "Characteristics of Synchrotron Radiation and of itsHandbook on Synchrotron Radiation, E. -E. Koch.1A. 65-172,

Howells, M.R.

2011-01-01T23:59:59.000Z

389

Coherent Radiation in an Undulator  

E-Print Network (OSTI)

solving the particle-radiation system in a self-consistentto clarify the coherent radiation mechanism. References 1.the Proceedings Coherent Radiation in an Undulator Y,H. Chin

Chin, Y.H.

2011-01-01T23:59:59.000Z

390

Origins and consequences of radiation…induced centrosome aberrations  

NLE Websites -- All DOE Office Websites (Extended Search)

Origins and consequences of radiation-induced centrosome aberrations Origins and consequences of radiation-induced centrosome aberrations Sangeetha Vijayakumar, Nisarg Shah, Ignacio Fernandez-Garcia, Mary Helen Barcellos-Hoff Department of Radiation Oncology, New York University School of Medicine, NY, NY. Centrosome aberrations are frequently observed in pre-neoplastic breast lesions and are known to drive chromosomal instability (Lingle et al., 2002). Previous studies from our lab have shown that human mammary epithelial cells exposed to low doses of radiation exhibit centrosome aberrations (CAs) in a dose dependent manner from 10-200 cGy (Maxwell et al., 2008). These data demonstrated that radiation-induced CAs actually precede and generate genomic instability and that TGFβ is a key mediator

391

Low dose radiation combines with the Src oncoprotein to transform  

NLE Websites -- All DOE Office Websites (Extended Search)

radiation combines with the Src oncoprotein to transform radiation combines with the Src oncoprotein to transform pre-malignant human breast cells Paul Yaswen Lawrence Berkeley National Laboratory Abstract Goal: Determine whether low dose radiation exerts persistent epigenetic effects that promote malignancy. Background and Significance: Some persistent carcinogenic effects of radiation may not be traceable to specific DNA sequence alterations and may not be linearly related to dose. Through the biochemical initiation of positive feedback loops, ionization-induced events may have heritable non-linear effects on cellular behavior. Inflammatory responses involving the transcription factor NFκB may be subject to such effects. Increased NFκB activity has been strongly linked to carcinogenesis in a number of published in vitro and in vivo studies (reviewed in [1]). Since radiation

392

Florida Radiation Protection Act (Florida)  

Energy.gov (U.S. Department of Energy (DOE))

The Department of Public Health is responsible for administering a statewide radiation protection program. The program is designed to permit development and utilization of sources of radiation for...

393

NVLAP Radiation Detection Instruments LAP  

Science Conference Proceedings (OSTI)

Radiation Detection Instruments LAP. Leticia Pibida uses a hand-held radiation detection device to check cargo. Photo: Copyright Robert Rathe. ...

2013-07-23T23:59:59.000Z

394

Radiation Effects in Nanoporous Gold  

Science Conference Proceedings (OSTI)

Foams with filament and porous sizes in the range of nanometers could be unusually resistant to radiation because radiation induced point defects cannot...

395

Composition for radiation shielding  

DOE Patents (OSTI)

A composition for use as a radiation shield. The shield has a depleted urum core for absorbing gamma rays and a bismuth coating for preventing chemical corrosion and absorbing gamma rays. Alternatively, a sheet of gadolinium may be positioned between the uranium core and the bismuth coating for absorbing neutrons. The composition is preferably in the form of a container for storing materials that emit radiation such as gamma rays and neutrons. The container is preferably formed by casting bismuth around a pre-formed uranium container having a gadolinium sheeting, and allowing the bismuth to cool. The resulting container is a structurally sound, corrosion-resistant, radiation-absorbing container.

Kronberg, James W. (Aiken, SC)

1994-01-01T23:59:59.000Z

396

The Intense Radiation Gas  

E-Print Network (OSTI)

We present a new dispersion relation for photons that are nonlinearly interacting with a radiation gas of arbitrary intensity due to photon-photon scattering. It is found that the photon phase velocity decreases with increasing radiation intensity, it and attains a minimum value in the limit of super-intense fields. By using Hamilton's ray equations, a self-consistent kinetic theory for interacting photons is formulated. The interaction between an electromagnetic pulse and the radiation gas is shown to produce pulse self-compression and nonlinear saturation. Implications of our new results are discussed.

M. Marklund; P. K. Shukla; B. Eliasson

2004-10-14T23:59:59.000Z

397

Miniaturized radiation chirper  

SciTech Connect

The disclosure relates to a miniaturized radiation chirper for use with a small battery supplying on the order of 5 volts. A poor quality CdTe crystal which is not necessarily suitable for high resolution gamma ray spectroscopy is incorporated with appropriate electronics so that the chirper emits an audible noise at a rate that is proportional to radiation exposure level. The chirper is intended to serve as a personnel radiation warning device that utilizes new and novel electronics with a novel detector, a CdTe crystal. The resultant device is much smaller and has much longer battery life than existing chirpers.

Umbarger, C. John (Los Alamos, NM); Wolf, Michael A. (Los Alamos, NM)

1980-01-01T23:59:59.000Z

398

METHOD FOR MEASURING RADIATION  

DOE Patents (OSTI)

A method for measuring an unknown integrated quantity of radiation with a condenser ionization chamber is described. The chamber is initially charged to a predetermined voltage by a voltage source. The chamber is then removed from the source and exposed to an unknown quantity of radiation for a period of time. The quantity of radiation to which the chamber was exposed is then measured by detecting the magnitude of the pulse of current necessary to recharge the chamber of its initial value through a suitable impedance. The current pulse is amplified and measured directly by a suitable pulse height analyzing system. (AEC)

Roesch, W.C.; McCall, R.C.

1961-11-21T23:59:59.000Z

399

Proceedings: 2003 Radiation Protection Technology Conference  

SciTech Connect

Health physics professionals within the nuclear industry are continually upgrading their programs with new methods and technologies. The Third Annual EPRI Radiation Protection Technology Conference facilitated this effort by communicating technical developments, program improvements, and experience throughout the nuclear power industry. When viewed from the perspective of shorter outages, diminishing numbers of contract RP technicians and demanding emergent work, this information flow is critical for the industry.

None

2004-04-01T23:59:59.000Z

400

Proceedings: 2003 Radiation Protection Technology Conference  

Science Conference Proceedings (OSTI)

Health physics professionals within the nuclear industry are continually upgrading their programs with new methods and technologies. The Third Annual EPRI Radiation Protection Technology Conference facilitated this effort by communicating technical developments, program improvements, and experience throughout the nuclear power industry. When viewed from the perspective of shorter outages, diminishing numbers of contract RP technicians and demanding emergent work, this information flow is critical for the...

2004-04-13T23:59:59.000Z

Note: This page contains sample records for the topic "human radiation experiments" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


401

Ghost Imaging with Blackbody Radiation  

E-Print Network (OSTI)

We present a theoretical study of ghost imaging by using blackbody radiation source. A Gaussian thin lens equation for the ghost imaging, which depends on both paths, is derived. The dependences of the visibility and quality of the image on the transverse size and temperature of the blackbody are studied. The main differences between the ghost imaging by using the blackbody radiation and by using the entangled photon pairs are image-forming equation, and the visibility and quality of the image. PACS numbers: 42.30.Va, 42.25.Kb, 42.50.Ar, 42.25.Hz Ghost imaging were firstly realized by using entangled photon pairs generated in spontaneous parametric down conversion in 1995 [1,2]. The name ghost comes from the facts that an object in one path produces an image in another path in the measurement of coincident counting rates, and the image depends on both paths. Since then, many theoretical and experimental studies on this subject have been published [3-10]. Recently, there were discussions about whether quantum entanglement is necessary in the ghost imaging and whether a ghost imaging experiment can be realized with classical source [11-14]. Bennink et

Yangjian Cai; Shi-yao Zhu

2004-01-01T23:59:59.000Z

402

BNL NASA Space Radiation Laboratory  

NLE Websites -- All DOE Office Websites (Extended Search)

First Time Users Guide First Time Users Guide The following is a collection of useful facts that First Time Users of NSRL should familiarize themselves with. If you have any questions, contact the NSRL Liaison Physicist (631-344-3072 or 631-344-5830). You MUST have a dry run of your experiment before conducting your first NSRL run. When planning an exposure the time you need for each sample exposure should include time to change samples. If RHIC is running, the sample changing time is approximately 7 minutes. If RHIC is not running, time to change samples is only about 4 minutes. The size of the radiation field that can uniformly expose a set of samples can be as large as 20 x 20 cm2 for most ions and energies. By special request, the NSRL beam can operate in Large Beam mode with a 60 x 60 cm2 usable beam size.

403

ARM - Measurement - Backscattered radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

govMeasurementsBackscattered radiation govMeasurementsBackscattered radiation ARM Data Discovery Browse Data Comments? We would love to hear from you! Send us a note below or call us at 1-888-ARM-DATA. Send Measurement : Backscattered radiation The scattering of radiant energy into the hemisphere of space bounded by a plane normal to the direction of the incident radiation and lying on the same side as the incident ray. Categories Aerosols, Cloud Properties Instruments The above measurement is considered scientifically relevant for the following instruments. Refer to the datastream (netcdf) file headers of each instrument for a list of all available measurements, including those recorded for diagnostic or quality assurance purposes. ARM Instruments AOS : Aerosol Observing System IAP : In-situ Aerosol Profiles (Cessna Aerosol Flights)

404

Ionizing radiation detector  

DOE Patents (OSTI)

An ionizing radiation detector is provided which is based on the principal of analog electronic integration of radiation sensor currents in the sub-pico to nano ampere range between fixed voltage switching thresholds with automatic voltage reversal each time the appropriate threshold is reached. The thresholds are provided by a first NAND gate Schmitt trigger which is coupled with a second NAND gate Schmitt trigger operating in an alternate switching state from the first gate to turn either a visible or audible indicating device on and off in response to the gate switching rate which is indicative of the level of radiation being sensed. The detector can be configured as a small, personal radiation dosimeter which is simple to operate and responsive over a dynamic range of at least 0.01 to 1000 R/hr.

Thacker, L.H.

1989-06-08T23:59:59.000Z

405

Amorphous silicon radiation detectors  

DOE Patents (OSTI)

Hydrogenated amorphous silicon radiation detector devices having enhanced signal are disclosed. Specifically provided are transversely oriented electrode layers and layered detector configurations of amorphous silicon, the structure of which allow high electric fields upon application of a bias thereby beneficially resulting in a reduction in noise from contact injection and an increase in signal including avalanche multiplication and gain of the signal produced by incoming high energy radiation. These enhanced radiation sensitive devices can be used as measuring and detection means for visible light, low energy photons and high energy ionizing particles such as electrons, x-rays, alpha particles, beta particles and gamma radiation. Particular utility of the device is disclosed for precision powder crystallography and biological identification.

Street, Robert A. (Palo Alto, CA); Perez-Mendez, Victor (Berkeley, CA); Kaplan, Selig N. (El Cerrito, CA)

1992-01-01T23:59:59.000Z

406

Amorphous silicon radiation detectors  

DOE Patents (OSTI)

Hydrogenated amorphous silicon radiation detector devices having enhanced signal are disclosed. Specifically provided are transversely oriented electrode layers and layered detector configurations of amorphous silicon, the structure of which allow high electric fields upon application of a bias thereby beneficially resulting in a reduction in noise from contact injection and an increase in signal including avalanche multiplication and gain of the signal produced by incoming high energy radiation. These enhanced radiation sensitive devices can be used as measuring and detection means for visible light, low energy photons and high energy ionizing particles such as electrons, x-rays, alpha particles, beta particles and gamma radiation. Particular utility of the device is disclosed for precision powder crystallography and biological identification. 13 figs.

Street, R.A.; Perez-Mendez, V.; Kaplan, S.N.

1992-11-17T23:59:59.000Z

407

Ionizing radiation detector  

DOE Patents (OSTI)

An ionizing radiation detector is provided which is based on the principle of analog electronic integration of radiation sensor currents in the sub-pico to nano ampere range between fixed voltage switching thresholds with automatic voltage reversal each time the appropriate threshold is reached. The thresholds are provided by a first NAND gate Schmitt trigger which is coupled with a second NAND gate Schmitt trigger operating in an alternate switching state from the first gate to turn either a visible or audible indicating device on and off in response to the gate switching rate which is indicative of the level of radiation being sensed. The detector can be configured as a small, personal radiation dosimeter which is simple to operate and responsive over a dynamic range of at least 0.01 to 1000 R/hr.

Thacker, Louis H. (Knoxville, TN)

1990-01-01T23:59:59.000Z

408

Portal radiation monitor  

DOE Patents (OSTI)

A portal radiation monitor combines 0.1% FAR with high sensitivity to special nuclear material. The monitor utilizes pulse shape discrimination, dynamic compression of the photomultiplier output and scintillators sized to maintain efficiency over the entire portal area.

Kruse, Lyle W. (Albuquerque, NM)

1985-01-01T23:59:59.000Z

409

Radiation Stress Estimators  

Science Conference Proceedings (OSTI)

The radiation stresses Sij associated with the propagation of wind-generated waves are principal driving forces for several important surf-zone processes. The accurate estimation of the onshore flux of longshore-directed mean momentum Syx, using ...

S. S. Pawka; D. L. Inman; R. T. Guza

1983-09-01T23:59:59.000Z

410

Adaptive multigroup radiation diffusion  

E-Print Network (OSTI)

This thesis describes the development and implementation of an algorithm for dramatically increasing the accuracy and reliability of multigroup radiation diffusion simulations at low group counts. This is achieved by ...

Williams, Richard B., Sc. D. Massachusetts Institute of Technology

2005-01-01T23:59:59.000Z

411

Flexible Composite Radiation Detector  

NLE Websites -- All DOE Office Websites (Extended Search)

Flexible Composite Radiation Detector Flexible Composite Radiation Detector Flexible Composite Radiation Detector A flexible composite scintillator was prepared by mixing fast, bright, dense rare-earth doped powdered oxyorthosilicate (such as LSO:Ce, LSO:Sm, and GSO:Ce) scintillator with a polymer binder. Available for thumbnail of Feynman Center (505) 665-9090 Email Flexible Composite Radiation Detector A flexible composite scintillator was prepared by mixing fast, bright, dense rare-earth doped powdered oxyorthosilicate (such as LSO:Ce, LSO:Sm, and GSO:Ce) scintillator with a polymer binder. The binder is transparent to the scintillator emission. The composite is seamless and can be made large and in a wide variety of shapes. Importantly, the composite can be tailored to emit light in a spectral region that matches the optimum

412

Method of enhancing radiation response of radiation detection materials  

DOE Patents (OSTI)

The present invention is a method of increasing radiation response of a radiation detection material for a given radiation signal by first pressurizing the radiation detection material. Pressurization may be accomplished by any means including mechanical and/or hydraulic. In this application, the term "pressure" includes fluid pressure and/or mechanical stress.

Miller, Steven D. (Richland, WA)

1997-01-01T23:59:59.000Z

413

Low Dose Radiation Program: Links - Agencies with Radiation Regulatory  

NLE Websites -- All DOE Office Websites (Extended Search)

Agencies with Radiation Regulatory Concerns and Involvement Agencies with Radiation Regulatory Concerns and Involvement Biological Effects of Low Level Exposures (BELLE) Canadian Nuclear Safety Commission Center for Risk Excellence Health Protection Agency The Health Risks of Extraterrestrial Environments International Commission on Radiation Units and Measurements, Inc. International Commission on Radiological Protection (ICRP) International Radiation Protection Association (IRPA) NASA Space Radiation Program National Academy of Sciences (NAS) Nuclear and Radiation Studies Board National Aeronautics and Space Administration (NASA) NASA OBRR Task Book Publication National Council on Radiation Protection (NCRP) National Institute of Environmental Health Sciences (NIEHS) National Toxicology Program (NTP) Occupational Safety and Health Administration (OSHA)

414

Low Dose Radiation Research Program: Effects of Low Doses of Radiation on  

NLE Websites -- All DOE Office Websites (Extended Search)

Low Doses of Radiation on DNA Repair Low Doses of Radiation on DNA Repair Eric Ackerman Pacific Northwest National Laboratory Why this Project? Even low doses (0.1 Gy) exert measurable effects on DNA repair. The first-known oxidative lesion repaired only by nucleotide excision repair found in normal cells is cyclo-dA. This lesion is found in normal cells and thought to be a byproduct of oxidative metabolism. When this lesion occurs, it stimulates repair. If repair is stimulated by low dose radiation, there are some implications for human health. For example, do some individuals exhibit a greater, lower, or no stimulation to certain DNA lesions? If there are population polymorphism that influence DNA repair, then it would be possible to use our assay for screening individuals for repair sensitivity.

415

Packet personal radiation monitor  

DOE Patents (OSTI)

A personal radiation monitor of the chirper type is provided for detecting ionizing radiation. A battery powered high voltage power supply is used to generate and apply a high voltage bias to a G-M tube radiation sensor. The high voltage is monitored by a low-loss sensing network which generates a feedback signal to control the high voltage power supply such that the high voltage bias is recharged to +500 VDC when the current pulses of the sensor, generated by the detection of ionizing radiation events, discharges the high voltage bias to +450 VDC. During the high voltage recharge period an audio transducer is activated to produce an audible "chirp". The rate of the "chirps" is controlled by the rate at which the high voltage bias is recharged, which is proportional to the radiation field intensity to which the sensor is exposed. The chirp rate sensitivity is set to be approximately 1.5 (chirps/min/MR/hr.). The G-M tube sensor is used in a current sensing mode so that the device does not paralyze in a high radiation field.

Phelps, James E. (Knoxville, TN)

1989-01-01T23:59:59.000Z

416

Low Dose Radiation Research Program: Multi-cellular Crosstalk in Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

About this Project About this Project Multi-cellular Crosstalk in Radiation Damage Technical Abstracts 2006 Workshop: Low-LET Bystander Effects in Cells In Vitro Are Significantly Less Than Published For High-LET Radiation Blakely, E.A., Thompson, A.C., Chang, P., Schwarz, R.I., Bjornstad, K., Rosen, C., Wisnewski, C., and Mocherla, D. 2005 Workshop: X-ray Microbeam Bystander Studies with Human Mammary Epithelial Cells and Fibroblasts Blakely, E.A., Schwarz, R.I., Thompson, A.C., Bjornstad, K.A., Chang, P.Y., Rosen, C.J., Sudar, D., Romano, R., and Parvin, B. 2003 Workshop: 12.5 keV X-ray Microbeam Bystander Studies with Human Mammary Epithelial Cells and Fibroblasts Blakely, E.A., Schwarz, R.I., Thompson, A.C., Bjornstad, K.A., Chang, P.Y., Rosen, C.J., and Sudar, D. 2001 Workshop:

417

EXPERIMENTS MODEL PK-101  

E-Print Network (OSTI)

to Quizzes 3 Introduction to Basic Components 4 Experiment #1: The Light Bulb 8 More About Resistors 10 Detector 17 Introduction to Capacitors 18 Experiment #8: Slow Light Bulb 20 Experiment #9: Small Dominates Light Bulbs 26 Introduction to Transistors 27 Experiment #14: The Electronic Switch 28 Experiment #15

Kachroo, Pushkin

418

Mathematical model for predicting the probability of acute mortality in a human population exposed to accidentally released airborne radionuclides. Final report for Phase I  

SciTech Connect

A mathematical model was constructed for the purpose of predicting the fraction of human population which would die within 1 year of an accidental exposure to airborne radionuclides. The model is based on data from laboratory experiments with rats, dogs and baboons, and from human epidemiological data. Doses from external, whole-body irradiation and from inhaled, alpha- and beta-emitting radionuclides are calculated for several organs. The probabilities of death from radiation pneumonitis and from bone marrow irradiation are predicted from doses accumulated within 30 days of exposure to the radioactive aerosol. The model is compared with existing similar models under hypothetical exposure conditions. Suggestions for further experiments with inhaled radionuclides are included. 25 refs., 16 figs., 13 tabs.

Filipy, R.E.; Borst, F.J.; Cross, F.T.; Park, J.F.; Moss, O.R.; Roswell, R.L.; Stevens, D.L.

1980-05-01T23:59:59.000Z

419

Experiment Hazard Class 10.2 - UV Light  

NLE Websites -- All DOE Office Websites (Extended Search)

2 - Ultraviolet Light 2 - Ultraviolet Light Applicability This hazard classification applies to all experiments involving the use of ultraviolet radiation generating equipment.Ultraviolet light (UV) is non-ionizing radiation in the 180 to 400-nanometer wavelength region of the electromagnetic spectrum. Ultraviolet light poses hazards: Eyes hazards - inflammation, cataracts, retinal damage Skin hazards - sunburn, accelerate wrinkling, increased risk of skin cancer Invisible Possible ozone generation Experiment Category Experiments involving only experiment hazard class 10.2 qualify for medium risk. The addition of other hazard classes may require the experiment to be categorized as high risk and undergo additional reviews. Experiment Hazard Control Verification Statements Engineered Controls - Shield or contain UV as close to the source as

420

NIST Ionizing Radiation Division - 1998  

Science Conference Proceedings (OSTI)

TECHNICAL ACTIVITIES 1998 - NISTIR 6268 IONIZING RADIATION DIVISION. The Neutron Interferometer. The neutron ...

Note: This page contains sample records for the topic "human radiation experiments" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


421

NIST Ionizing Radiation Division - 2000  

Science Conference Proceedings (OSTI)

"Technical Activities 2000" - Table of Contents, Division home page. Ionizing Radiation Division. ...

422

An Instrumentation Complex for Atmospheric Radiation Measurements in Siberia  

NLE Websites -- All DOE Office Websites (Extended Search)

Instrumentation Complex for Atmospheric Radiation Instrumentation Complex for Atmospheric Radiation Measurements in Siberia S. M. Sakerin, F. V. Dorofeev, D. M. Kabanov, V. S. Kozlov, M. V. Panchenko, Yu. A. Pkhalagov, V. V. Polkin, V. P. Shmargunov, S. A. Terpugova, S. A. Turchinovich, and V. N. Uzhegov Institute of Atmospheric Optics Tomsk, Russia Introduction The instrumentation complex is described, which has been prepared for radiative experiments in the region of Tomsk (West Siberia). The complex consists of three groups of devices to measure (a) the characteristics of the total downward radiation; (b) the most variable components of the atmospheric transparency directly affecting the income of radiation (aerosol optical depth [AOD], total content of water vapor, ozone, etc.); and (c) aerosol and meteorological parameters of the near-ground layer of the

423

Low-Dose Ionizing Radiation Alters the Epigenome of the Avy Mouse  

NLE Websites -- All DOE Office Websites (Extended Search)

Medical Center Abstract Background: Humans have evolved and thrived amidst constant low-dose (0-10 cGy) background radiation exposure from natural sources. Currently, however, the...

424

Radiation in Particle Simulations  

SciTech Connect

Hot dense radiative (HDR) plasmas common to Inertial Confinement Fusion (ICF) and stellar interiors have high temperature (a few hundred eV to tens of keV), high density (tens to hundreds of g/cc) and high pressure (hundreds of megabars to thousands of gigabars). Typically, such plasmas undergo collisional, radiative, atomic and possibly thermonuclear processes. In order to describe HDR plasmas, computational physicists in ICF and astrophysics use atomic-scale microphysical models implemented in various simulation codes. Experimental validation of the models used to describe HDR plasmas are difficult to perform. Direct Numerical Simulation (DNS) of the many-body interactions of plasmas is a promising approach to model validation but, previous work either relies on the collisionless approximation or ignores radiation. We present four methods that attempt a new numerical simulation technique to address a currently unsolved problem: the extension of molecular dynamics to collisional plasmas including emission and absorption of radiation. The first method applies the Lienard-Weichert solution of Maxwell's equations for a classical particle whose motion is assumed to be known. The second method expands the electromagnetic field in normal modes (planewaves in a box with periodic boundary-conditions) and solves the equation for wave amplitudes coupled to the particle motion. The third method is a hybrid molecular dynamics/Monte Carlo (MD/MC) method which calculates radiation emitted or absorbed by electron-ion pairs during close collisions. The fourth method is a generalization of the third method to include small clusters of particles emitting radiation during close encounters: one electron simultaneously hitting two ions, two electrons simultaneously hitting one ion, etc. This approach is inspired by the virial expansion method of equilibrium statistical mechanics. Using a combination of these methods we believe it is possible to do atomic-scale particle simulations of fusion ignition plasmas including the important effects of radiation emission and absorption.

More, R; Graziani, F; Glosli, J; Surh, M

2010-11-19T23:59:59.000Z

425

Oak Ridge Integrated Center for Radiation Materials Science & Technology  

NLE Websites -- All DOE Office Websites (Extended Search)

ORIC Home ORIC Home About ORIC Contacts Specialists Capabilities Irradiation Campaigns Nuclear Fuels Radiation Effects and Defect Modeling Structural Materials Dual Purpose Radiological Characterization Equipment Working with Us Related Links HFIR MSTD NSTD NNFD Comments Welcome to Oak Ridge Integrated Center for Radiation Materials Science & Technology The Oak Ridge National Laboratory ranks among the founding laboratories for the scientific field of radiation materials science. Since the creation of the laboratory, we have maintained strong ties to both the technology and scientific underpinning of nuclear materials research as evidenced by the experience and capabilities across our research divisions. The capabilities at ORNL enjoys include the highest neutron flux nuclear

426

Imprint of Sterile Neutrinos in the Cosmic Microwave Background Radiation  

E-Print Network (OSTI)

The existence of low-mass sterile neutrinos is suggested by the current status of solar and atmospheric neutrinos together with the LSND experiment. In typical four-flavor scenarios, neutrinos would contribute to a cosmic hot dark matter component and to an increased radiation content at the epoch of matter-radiation equality. These effects leave their imprint in sky maps of the cosmic microwave background radiation (CMBR) and may thus be detectable with the precision measurements of the upcoming MAP and PLANCK missions.

Steen Hannestad; Georg Raffelt

1998-05-17T23:59:59.000Z

427

Radiation delivery system and method  

DOE Patents (OSTI)

A radiation delivery system and method are described. The system includes a treatment configuration such as a stent, balloon catheter, wire, ribbon, or the like, a portion of which is covered with a gold layer. Chemisorbed to the gold layer is a radiation-emitting self-assembled monolayer or a radiation-emitting polymer. The radiation delivery system is compatible with medical catheter-based technologies to provide a therapeutic dose of radiation to a lesion following an angioplasty procedure.

Sorensen, Scott A. (Overland Park, KS); Robison, Thomas W. (Los Alamos, NM); Taylor, Craig M. V. (Jemez Springs, NM)

2002-01-01T23:59:59.000Z

428

Aerial radiation survey at a military range.  

SciTech Connect

Aberdeen Proving Ground (APG) is currently listed on the Superfund National Priorities List because of past waste handling practices at 13 'study areas.' Concern has been expressed that anthropogenic radioisotopes may have been released at some of the study areas, with the potential of posing health risks to human or ecological receptors. This concern was addressed by thoroughly searching archival records, sampling and analyzing environmental media, and performing an aerial radiation survey. The aerial radiation survey techniques employed have been used over all U.S. Department of Energy and commercial reactor sites. Use of the Aerial Measurement System (AMS) allowed investigators to safely survey areas where surveys using hand-held instruments would be difficult to perform. In addition, the AMS delivered a full spectrum of the measured gamma radiation, thereby providing a means of determining which radioisotopes were present at the surface. As a quality check on the aerial measurements, four ground truth measurements were made at selected locations and compared with the aerial data for the same locations. The results of the survey revealed no evidence of surface radioactive contamination. The measured background radiation, including the cosmic contribution, ranged from 4 to 11 {mu}R/h.

Williams, G. P.; Martino, L. E.; Wrobel, J.; Environmental Assessment; U.S. Army Aberdeen Proving Ground

2001-04-01T23:59:59.000Z

429

Operating Experience Summaries  

NLE Websites -- All DOE Office Websites (Extended Search)

Operating Experience Summaries The Office of Health, Safety and Security (HSS) Office of Analysis publishes the Operating Experience Summary to exchange lessons-learned information...

430

Radiation Measurements 42 (2007) 10291032 www.elsevier.com/locate/radmeas  

E-Print Network (OSTI)

for internalized DU exposure. The purpose of the current study was to measure the induction of mutagenic damageRadiation Measurements 42 (2007) 1029­1032 www.elsevier.com/locate/radmeas Observation of radiation demonstrated that DU exposure in vitro to immortalized human osteoblast cells (HOS) is both neoplastically

431

Nuclear radiation actuated valve  

DOE Patents (OSTI)

A nuclear radiation actuated valve for a nuclear reactor. The valve has a valve first part (such as a valve rod with piston) and a valve second part (such as a valve tube surrounding the valve rod, with the valve tube having side slots surrounding the piston). Both valve parts have known nuclear radiation swelling characteristics. The valve's first part is positioned to receive nuclear radiation from the nuclear reactor's fuel region. The valve's second part is positioned so that its nuclear radiation induced swelling is different from that of the valve's first part. The valve's second part also is positioned so that the valve's first and second parts create a valve orifice which changes in size due to the different nuclear radiation caused swelling of the valve's first part compared to the valve's second part. The valve may be used in a nuclear reactor's core coolant system.

Christiansen, David W. (Kennewick, WA); Schively, Dixon P. (Richland, WA)

1985-01-01T23:59:59.000Z

432

AREA RADIATION MONITOR  

DOE Patents (OSTI)

S>An improved area radiation dose monitor is designed which is adapted to compensate continuously for background radiation below a threshold dose rate and to give warning when the dose integral of the dose rate of an above-threshold radiation excursion exceeds a selected value. This is accomplished by providing means for continuously charging an ionization chamber. The chamber provides a first current proportional to the incident radiation dose rate. Means are provided for generating a second current including means for nulling out the first current with the second current at all values of the first current corresponding to dose rates below a selected threshold dose rate value. The second current has a maximum value corresponding to that of the first current at the threshold dose rate. The excess of the first current over the second current, which occurs above the threshold, is integrated and an alarm is given at a selected integrated value of the excess corresponding to a selected radiation dose. (AEC)

Manning, F.W.; Groothuis, S.E.; Lykins, J.H.; Papke, D.M.

1962-06-12T23:59:59.000Z

433

Remote radiation dosimetry  

DOE Patents (OSTI)

Disclosed are methods and apparatus for remotely measuring radiation levels. Such are particularly useful for measuring relatively high levels or dosages of radiation being administered in radiation therapy. They are also useful for more general radiation level measurements where remote sensing from the remaining portions of the apparatus is desirable. The apparatus uses a beam generator, such as a laser beam, to provide a stimulating beam. The stimulating beam is preferably of wavelengths shorter than 6 microns, or more advantageously less than 2 microns. The stimulating beam is used to stimulate a remote luminescent sensor mounted in a probe which emits stored luminescent energy resulting from exposure of the sensor to ionizing radiation. The stimulating beam is communicated to the remote luminescent sensor via transmissive fiber which also preferably serves to return the emission from the luminescent sensor. The stimulating beam is advantageously split by a beam splitter to create a detector beam which is measured for power during a reading period during which the luminescent phosphor is read. The detected power is preferably used to control the beam generator to thus produce desired beam power during the reading period. The luminescent emission from the remote sensor is communicated to a suitable emission detector, preferably after filtering or other selective treatment to better isolate the luminescent emission.

Braunlich, Peter F. (Pullman, WA); Tetzlaff, Wolfgang (Pullman, WA); Hegland, Joel E. (Pullman, WA); Jones, Scott C. (Pullman, WA)

1991-01-01T23:59:59.000Z

434

Remote radiation dosimetry  

DOE Patents (OSTI)

Disclosed are methods and apparatus for remotely measuring radiation levels. Such are particularly useful for measuring relatively high levels or dosages of radiation being administered in radiation therapy. They are also useful for more general radiation level measurements where remote sensing from the remaining portions of the apparatus is desirable. The apparatus uses a beam generator, such as a laser beam, to provide a stimulating beam. The stimulating beam is preferably of wavelengths shorter than 6 microns, or more advantageously less than 2 microns. The stimulating beam is used to stimulate a remote luminescent sensor mounted in a probe which emits stored luminescent energy resulting from exposure of the sensor to ionizing radiation. The stimulating beam is communicated to the remote luminescent sensor via a transmissive fiber which also preferably serves to return the emission from the luminescent sensor. The stimulating beam is advantageously split by a beam splitter to create a detector beam which is measured for power during a reading period during which the luminescent phosphor is read. The detected power is preferably used to control the beam generator to thus produce desired beam power during the reading period. The luminescent emission from the remote sensor is communicated to a suitable emission detector, preferably after filtering or other selective treatment to better isolate the luminescent emission. 8 figures.

Braunlich, P.F.; Tetzlaff, W.; Hegland, J.E.; Jones, S.C.

1991-03-12T23:59:59.000Z

435

Packet personal radiation monitor  

DOE Patents (OSTI)

A personal radiation monitor of the chirper type is provided for detecting ionizing radiation. A battery powered high voltage power supply is used to generate and apply a high voltage bias to a G-M tube radiation sensor. The high voltage is monitored by a low-loss sensing network which generates a feedback signal to control the high voltage power supply such that the high voltage bias is recharged to +500 VDC when the current pulses of the sensor, generated by the detection of ionizing radiatonevents, discharges the high voltage bias to +450 VDC. During the high voltage recharge period an audio transducer is activated to produce an audible ''chirp''. The rate of the ''chirps'' is controlled by the rate at which the high voltage bias is recharged, which is proportional to the radiation field intensity to which the sensor is exposed. The chirp rate sensitivity is set to be approximately 1.5 (chirps/min/MR/hr.). The G-M tube sensor is used in a current sensing mode so that the device does not paralyze in a high radiation field. 2 figs.

Phelps, J.E.

1988-03-31T23:59:59.000Z

436

Fermilab | Science at Fermilab | Experiments & Projects | Experiments...  

NLE Websites -- All DOE Office Websites (Extended Search)

Particle Physics News Image Bank Fermilab in the News Quantum Diaries In this Section: Energy Frontier Intensity Frontier Cosmic Frontier Experiments at the Cosmic Frontier How...

437

Low Dose Radiation Program: Links - Organizations Conducting Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Conducting Low Dose Radiation Research Conducting Low Dose Radiation Research DOE Low Dose Radiation Research Program DoReMi Integrating Low Dose Research High Level Expert Group (HLEG) on European Low Dose Risk Research Multidisciplinary European Low Dose Initiative (MELODI) RISC-RAD Radiosensitivity of Individuals and Susceptibility to Cancer induced by Ionizing Radiation United States Transuranium & Uranium Registries Organizations Conducting other Radiation Research Argonne National Laboratory (ANL) Armed Forces Radiology Research Institute (AFRRI) Atmospheric Radiation Measurement (ARM) Program Brookhaven National Laboratory (BNL) Center for Devices and Radiological Health (CDRH) Central Research Institute of Electric Power Industry (CRIEPI) Colorado State University Columbia University

438

Composition for radiation shielding  

DOE Patents (OSTI)

A composition for use as a radiation shield is disclosed. The shield has a depleted uranium core for absorbing gamma rays and a bismuth coating for preventing chemical corrosion and absorbing gamma rays. Alternatively, a sheet of gadolinium may be positioned between the uranium core and the bismuth coating for absorbing neutrons. The composition is preferably in the form of a container for storing materials that emit radiation such as gamma rays and neutrons. The container is preferably formed by casting bismuth around a pre-formed uranium container having a gadolinium sheeting, and allowing the bismuth to cool. The resulting container is a structurally sound, corrosion-resistant, radiation-absorbing container. 2 figs.

Kronberg, J.W.

1994-08-02T23:59:59.000Z

439

Audible radiation monitor  

DOE Patents (OSTI)

This invention consists of a method and apparatus for monitoring ionizing radiation comprising radiation detectors in electrical connection with an isotopic analyzer and a device for producing chords to which each isotope is mapped so that the device produces a unique chord for each isotope. Preferably the chords are pleasing to the ear, except for chords representing unexpected isotopes, and are louder or softer depending on the level of radioactivity produced by each isotope, and musical instrument voices may be simulated in producing the chords as an aid to distinguishing similar-sounding chords. Because of the representation by chords, information regarding the level and composition of the radiation in an area can be conveyed to workers in that area more effectively and yet without distracting them.

Odell, D.M.C.

1992-12-31T23:59:59.000Z

440

Semiconductor radiation detector  

DOE Patents (OSTI)

A semiconductor detector for ionizing electromagnetic radiation, neutrons, and energetic charged particles. The detecting element is comprised of a compound having the composition I-III-VI.sub.2 or II-IV-V.sub.2 where the "I" component is from column 1A or 1B of the periodic table, the "II" component is from column 2B, the "III" component is from column 3A, the "IV" component is from column 4A, the "V" component is from column 5A, and the "VI" component is from column 6A. The detecting element detects ionizing radiation by generating a signal proportional to the energy deposited in the element, and detects neutrons by virtue of the ionizing radiation emitted by one or more of the constituent materials subsequent to capture. The detector may contain more than one neutron-sensitive component.

Bell, Zane W. (Oak Ridge, TN); Burger, Arnold (Knoxville, TN)

2010-03-30T23:59:59.000Z

Note: This page contains sample records for the topic "human radiation experiments" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


441

Lung cancer mortality between 1950 and 1987 after exposure to fractionated moderate-dose-rate ionizing radiation in the Canadian fluoroscopy cohort study and a comparison with lung cancer mortality in the atomic bomb survivors study  

Science Conference Proceedings (OSTI)

Current lung cancer risk estimates after exposure to low-linear energy transfer radiation such as X rays are based on studies of people exposed to such radiation at high dose rates, for example the atomic bomb survivors. Radiobiology and animal experiments suggest that risks from exposure at low to moderate dose rates, for example medical diagnostic procedures, may be overestimated by such risk models, but data for humans to examine this issue are limited. In this paper we report on lung cancer mortality between 1950 and 1987 in a cohort of 64,172 Canadian tuberculosis patients, of whom 39% were exposed to highly fractionated multiple chest fluoroscopies leading to a mean lung radiation dose of 1.02 Sv received at moderate dose rates. These data have been used to estimate the excess relative risk per sievert of lung cancer mortality, and this is compared directly to estimates derived from 75,991 atomic bomb survivors. Based on 1,178 lung cancer deaths in the fluoroscopy study, there was no evidence of any positive association between risk and dose, with the relative risk at 1 Sv being 1.00 (95% confidence interval 0.94, 1.07), which contrasts with that based on the atomic bomb survivors, 1.60 (1.27, 1.99). The difference in effect between the two studies almost certainly did not arise by chance (P = 0.0001). This study provides strong support from data for humans for a substantial fractionation/dose-rate effect for low-linear energy transfer radiation and lung cancer risk. This implies that lung cancer risk from exposures to such radiation at present-day dose rates is likely to be lower than would be predicted by current radiation risk models based on studies of high-dose-rate exposures. 25 refs., 8 tabs.

Howe, G.R. [Univ. of Toronto, Ontario (Canada)

1995-06-01T23:59:59.000Z

442

Gravimagnetic shock waves and gravitational-wave experiments  

E-Print Network (OSTI)

Causes of the unsatisfactory condition of the gravitational-wave experiments are discussed and a new outlook at the detection of gravitational waves of astrophysical origin is proposed. It is shown that there are strong grounds for identifying the so-called giant pulses in the pulsar NP 0532 radiation with gravimagnetic shock waves (GMSW) excited in the neutron star magnetosphere by sporadic gravitational radiation of this pulsar.

Yu. G. Ignatyev

2011-01-09T23:59:59.000Z

443

RADCAL Operations Manual Radiation Calibration Laboratory Protocol  

SciTech Connect

The Life Sciences Division (LSD) of Oak Ridge National Laboratory (ORNL) has a long record of radiation dosimetry research, primarily using the Health Physics Research Reactor (HPRR) and the Radiation Calibration Laboratory (RADCAL) in its Dosimetry Applications Research (DOSAR) Program. These facilities have been used by a broad segment of the research community to perform a variety of experiments in areas including, but not limited to, radiobiology, radiation dosimeter and instrumentation development and calibration, and the testing of materials in a variety of radiation environments. Operations of the HPRR were terminated in 1987 and the reactor was moved to storage at the Oak Ridge Y-12 Plant; however, RADCAL will continue to be operated in accordance with the guidelines of the National Institute of Standards and Technology (NIST) Secondary Calibration Laboratory program and will meet all requirements for testing dosimeters under the National Voluntary Laboratory Accreditation Program (NVLAP). This manual is to serve as the primary instruction and operation manual for the Oak Ridge National Laboratory's RADCAL facility. Its purpose is to (1) provide operating protocols for the RADCAL facility, (2) outline the organizational structure, (3) define the Quality Assurance Action Plan, and (4) describe all the procedures, operations, and responsibilities for the safe and proper operation of all routine aspects of the calibration facility.

Bogard, J.S.

1998-12-01T23:59:59.000Z

444

Low Dose Radiation Research Program: Induction of Genomic Instability in  

NLE Websites -- All DOE Office Websites (Extended Search)

Induction of Genomic Instability in vivo by Low Doses of 137Cs y Induction of Genomic Instability in vivo by Low Doses of 137Cs y rays, Authors: K. Rithidech1, E.B. Whorton2, M. Tungjai1, E. Ar-Bab1, S.R. Simon1, M. Tawde3 and C.W. Anderson3. Institutions: 1Pathology Department, Stony Brook University, NY 11794-8691, USA, 2University of Texas Medical Branch at Galveston, TX 77550-1047,3Biology Department, Brookhaven National Laboratory, Upton, NY 11973-5000. Information on potential health hazards of radiation at doses below or equal to the level traditionally requiring human radiation protection (less than or equal to 10 cGy) is currently lacking. It is therefore important to characterize early and subsequent in vivo biological response induced by low doses of ionizing radiation because such data should provide information that can help determine whether radiation at this dose level

445

Low Dose Radiation Research Program: Molecular Mechanisms of  

NLE Websites -- All DOE Office Websites (Extended Search)

Molecular Mechanisms of Radiation-Induced Genomic Instability in Molecular Mechanisms of Radiation-Induced Genomic Instability in Human Cells. Authors: Howard L. Liber1 and Jeffrey L. Schwartz2. Institutions: 1Colorado State University and 2University of Washington. Knowledge of the signal and target through which radiation induces genomic instability, which we propose to investigate herein, will allow us to model effects at low doses. Such knowledge will aid in understanding variations in the induction of this genomic instability, both among cells and among individuals. This information could also lead to more sensitive measures of instability that could yield accurate measures of instability induction at low doses. We have developed an in-vitro cell model, in which radiation-induced chromosome instability develops in a two-stage process.

446

Low Dose Radiation Research Program: Marianne B. Sowa  

NLE Websites -- All DOE Office Websites (Extended Search)

Marianne B. Sowa Marianne B. Sowa PNNL - Pacific Northwest National Laboratory Funded Projects A Mechanistic Study of the Radiation Quality Dependence of Bystander Effects in Human Cells Technical Abstracts 2006 Workshop: Using a Low-LET Electron Microbeam to Investigate Non-Targeted Effects of Low Dose Radiation. Sowa, M.B., Goetz, W., Baulch, J., and Morgan, W.F. Morphological Changes in a 3D Mammary Model Following Exposure to Low Dose, Low-LET Radiation Opresko, L.K., Chrisler, W., Emory, K., Arthurs, B., and Sowa, M.B. 2005 Workshops: Using a Low LET Electron Microbeam to Investigate Non-Targeted Effects of Low Dose Radiation Morgan, W.F. and Sowa, M.B. Publications Perrine, K.A., Lamarche, B.L., Hopkins, D.F., Budge, S.E., Opresko, L.K., Wiley, H.S., and Sowa, M.B. (2007). High speed method for in situ

447

Biological Basis for Radiation Adaptive Responses that Protect Against  

NLE Websites -- All DOE Office Websites (Extended Search)

Basis for Radiation Adaptive Responses that Protect Against Basis for Radiation Adaptive Responses that Protect Against Bronchial Epithelial Cell Transformation Wenshu Chen Lovelace Respiratory Research Institute Abstract The major hypothesis in this project is that low-dose, low linear-energy-transfer (LET) radiation stimulates an adaptive response that protects cells from neoplastic transformation involving modulation of paracrine factors (e.g., cytokines), cell survival/death signaling pathways, and reprogramming of the epigenome. To test this hypothesis, a validated, sensitive in vitro transformation model and a media transfer method were used to study the mechanisms of low-LET gamma radiation activated natural protection (ANP) against chemical carcinogen-induced bronchial cell transformation. Immortalized human bronchial epithelial cell

448

Unruh radiation and Interference effect  

E-Print Network (OSTI)

A uniformly accelerated charged particle feels the vacuum as thermally excited and fluctuates around the classical trajectory. Then we may expect additional radiation besides the Larmor radiation. It is called Unruh radiation. In this report, we review the calculation of the Unruh radiation with an emphasis on the interference effect between the vacuum fluctuation and the radiation from the fluctuating motion. Our calculation is based on a stochastic treatment of the particle under a uniform acceleration. The basics of the stochastic equation are reviewed in another report in the same proceeding. In this report, we mainly discuss the radiation and the interference effect.

Iso, Satoshi; Zhang, Sen

2011-01-01T23:59:59.000Z

449

Unruh radiation and Interference effect  

E-Print Network (OSTI)

A uniformly accelerated charged particle feels the vacuum as thermally excited and fluctuates around the classical trajectory. Then we may expect additional radiation besides the Larmor radiation. It is called Unruh radiation. In this report, we review the calculation of the Unruh radiation with an emphasis on the interference effect between the vacuum fluctuation and the radiation from the fluctuating motion. Our calculation is based on a stochastic treatment of the particle under a uniform acceleration. The basics of the stochastic equation are reviewed in another report in the same proceeding. In this report, we mainly discuss the radiation and the interference effect.

Satoshi Iso; Yasuhiro Yamamoto; Sen Zhang

2011-02-23T23:59:59.000Z

450

Experiment Hazard Class 8.3 - X-Ray Generators  

NLE Websites -- All DOE Office Websites (Extended Search)

3 - X-Ray Generators 3 - X-Ray Generators Applicability This hazard classification applies to all experiments involving the use of X-Ray Generators (other than the APS storage ring). As specified in LMS-PROC-109 a Radiation Generating Device (RGD) must be registered with the Argonne RGD Safety Officer using the ANL-847 form. The RGD will be assigned an inventory number, hazard class, RWP requirement, and inspection and survey frequencies. Experiment Category Experiments the Experiment Hazard Class are always categorized as High Risk. Experiment Hazard Control Verification Statements Engineered Controls - As determined in LMS-PROC-109. Samples chambers and all beam paths are fully enclosed by barriers. Class 2 and higher RGDs require an interlock to fail-safe beam shutter/beam stop or radiation

451

A Rapid Radiative Transfer Model for Reflection of Solar Radiation  

Science Conference Proceedings (OSTI)

A rapid analytical radiative transfer model for reflection of solar radiation in plane-parallel atmospheres is developed based on the Sobolev approach and the delta function transformation technique. A distinct advantage of this model over ...

X. Xiang; E. A. Smith; C. G. Justus

1994-07-01T23:59:59.000Z

452

Toward Radiation-Resistant Ionic Liquids. Radiation Stability...  

NLE Websites -- All DOE Office Websites (Extended Search)

Radiation-Resistant Ionic Liquids. Radiation Stability of Sulfonyl Imide Anions I. A. Shkrob, T. W. Marin, Sergey D. Chemerisov, J. L. Hatcher, and J. F. Wishart J. Phys. Chem. B...

453

Radiation Source Replacement Workshop  

Science Conference Proceedings (OSTI)

This report summarizes a Radiation Source Replacement Workshop in Houston Texas on October 27-28, 2010, which provided a forum for industry and researchers to exchange information and to discuss the issues relating to replacement of AmBe, and potentially other isotope sources used in well logging.

Griffin, Jeffrey W.; Moran, Traci L.; Bond, Leonard J.

2010-12-01T23:59:59.000Z

454

Photovoltaic radiation detector element  

DOE Patents (OSTI)

A radiation detector element is formed of a body of semiconductor material, a coating on the body which forms a photovoltaic junction therewith, and a current collector consisting of narrow metallic strips, the aforesaid coating having an opening therein the edge of which closely approaches but is spaced from the current collector strips.

Agouridis, Dimitrios C. (Oak Ridge, TN)

1983-01-01T23:59:59.000Z

455

Local microwave background radiation  

E-Print Network (OSTI)

An inquiry on a possible local origin for the Microwave Background Radiation is made. Thermal MBR photons are contained in a system called {\\it magnetic bottle} which is due to Earth magnetic field and solar wind particles, mostly electrons. Observational tests are anticipated.

Domingos S. L. Soares

2006-07-11T23:59:59.000Z

456

Hyperon radiative decay  

SciTech Connect

The radiative decay widths of the low-lying strange baryons are calculated both within the relativistic quark bag model and the nonrelativistic potential model. These widths are found to depend sensitively upon the quark-model dynamics through multiplet mixing and q/sup 4/q-bar admixtures. The comparison between our calculated results and the very limited experimental data is discussed.

Kaxiras, E.; Moniz, E.J.; Soyeur, M.

1985-08-01T23:59:59.000Z

457

Radiation detector spectrum simulator  

SciTech Connect

A small battery operated nuclear spectrum simulator having a noise source nerates pulses with a Gaussian distribution of amplitudes. A switched dc bias circuit cooperating therewith generates several nominal amplitudes of such pulses and a spectral distribution of pulses that closely simulates the spectrum produced by a radiation source such as Americium 241.

Wolf, Michael A. (Los Alamos, NM); Crowell, John M. (Los Alamos, NM)

1987-01-01T23:59:59.000Z

458

Photovoltaic radiation detector element  

DOE Patents (OSTI)

A radiation detector element is formed of a body of semiconductor material, a coating on the body which forms a photovoltaic junction therewith, and a current collector consisting of narrow metallic strips, the aforesaid coating having an opening therein in the edge of which closely approaches but is spaced from the current collector strips.

Agouridis, D.C.

1980-12-17T23:59:59.000Z

459

STANFORD SYNCHROTRON RADIATION LIGHTSOURCE  

E-Print Network (OSTI)

-926-4100 SLAC is operated by Stanford University for the U.S. Department of Energy SSRL Facility Research Associate for Small Angle X-ray Scattering The Stanford Synchrotron Radiation Lightsource (SSRL) has) program. This position has a component (roughly 50%) that involves beam line development at SSRL

Ford, James

460

Radiation detector spectrum simulator  

DOE Patents (OSTI)

A small battery operated nuclear spectrum simulator having a noise source generates pulses with a Gaussian distribution of amplitudes. A switched dc bias circuit cooperating therewith to generate several nominal amplitudes of such pulses and a spectral distribution of pulses that closely simulates the spectrum produced by a radiation source such as Americium 241.

Wolf, M.A.; Crowell, J.M.

1985-04-09T23:59:59.000Z

Note: This page contains sample records for the topic "human radiation experiments" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


461

Low Dose Radiation Research Program: Molecular Mechanisms of  

NLE Websites -- All DOE Office Websites (Extended Search)

Molecular Mechanisms of Radiation-Induced Genomic Instability in Human Molecular Mechanisms of Radiation-Induced Genomic Instability in Human Cells Howard L. Liber Department of Environmental and Radiological Health Sciences Colorado State University Why This Project This research will be to investigate the condition known as genomic instability. This can be defined as a state in which genetic alterations, including chromosome aberrations and gene mutations, occur at rates that are much higher than normal. In fact, genomic instability is what allows a normal cell to accumulate the multiple genetic alterations that are required to convert it into a cancer cell. The chromosomes of human cells have structures at their ends called telomeres. Telomeres normally function to prevent chromosomes from fusing together end-to-end. An important

462

NREL Solar Radiation Resource Assessment Project: Status and outlook  

DOE Green Energy (OSTI)

This report summarizes the activities and accomplishments of NREL's Solar Radiation Resource Assessment Project during fiscal year 1991. Currently, the primary focus of the SRRAP is to produce a 1961--1990 National Solar Radiation Data Base, providing hourly values of global horizontal, diffuse, and direct normal solar radiation at approximately 250 sites around the United States. Because these solar radiation quantities have been measured intermittently at only about 50 of these sites, models were developed and applied to the majority of the stations to provide estimates of these parameters. Although approximately 93% of the data base consists of modeled data this represents a significant improvement over the SOLMET/ERSATZ 1952--1975 data base. The magnitude and importance of this activity are such that the majority of SRRAP human and financial in many other activities, which are reported here. These include the continued maintenance of a solar radiation monitoring network in the southeast United States at six Historically Black Colleges and Universities (HBCU's), the transfer of solar radiation resource assessment technology through a variety of activities, participation in international programs, and the maintenance and operation of NREL's Solar Radiation Research Laboratory. 17 refs.

Renne, D.; Riordan, C.; Maxwell, E.; Stoffel, T.; Marion, B.; Rymes, M.; Wilcox, S.; Myers, D.

1992-05-01T23:59:59.000Z

463

MEASUREMENT AND ANALYSIS OF CIRCUMSOLAR RADIATION  

E-Print Network (OSTI)

Character of Solar and Circumsolar Radiation. Proceedings ~all of the direct solar radiation (that originating from thethat attenuate the solar radiation available to terres-

Grether, Donald

2013-01-01T23:59:59.000Z

464

MEASUREMENT AND ANALYSIS OF CIRCUMSOLAR RADIATION  

E-Print Network (OSTI)

all of the direct solar radiation (that originating from thea suitable site for solar radiation measurements. A requestused to estimate the solar radiation per unit wavelength at

Grether, D.F.

2013-01-01T23:59:59.000Z

465

"Radiative Liquid Lithium (metal) Divertor" Inventor..-- Masayuki...  

NLE Websites -- All DOE Office Websites (Extended Search)

"Radiative Liquid Lithium (metal) Divertor" Inventor..-- Masayuki Ono The invention utilizes liquid lithium as a radiative material. The radiative process greatly reduces the...

466

TIME-RESOLVED SPECTROSCOPY USING SYNCHROTRON RADIATION  

E-Print Network (OSTI)

3395 (1977). H. Winick, VUV Radiation Physics, edited by E.M. W. Zemansky, Resonance Radiation and Exci- ted Atoms, (II. III. Appendix A - Radiation Trapping. Appendix B -

Poliakoff, E.D.

2010-01-01T23:59:59.000Z

467

Terahertz radiation from laser accelerated electron bunches  

E-Print Network (OSTI)

NUMBER 5 MAY 2004 Terahertz radiation from laser acceleratedand millimeter wave radiation from laser acceleratedNo. 5, May 2004 Terahertz radiation from laser accelerated

2004-01-01T23:59:59.000Z

468

Betatron radiation from density tailored plasmas  

E-Print Network (OSTI)

Betatron radiation from density tailored plasmas K. Tathe resulting betatron radiation spectrum can therefore bepro?le, the betatron radiation emitted by theses electrons

Ta Phuoc, Kim

2010-01-01T23:59:59.000Z

469

Probing Axions with Radiation from Magnetic Stars  

E-Print Network (OSTI)

Recent experiments suggest that polarized photons may couple significantly to pseudoscalar particles such as axions. We study the possible observational signatures of axion-photon coupling for radiation from magnetic stars, with particular focus on neutron stars. We present general methods for calculating the axion-photon conversion probability during propagation through a varying magnetized vacuum as well as across an inhomogeneous atmosphere. Partial axion-photon conversion may take place in the vacuum region outside the neutron star. Strong axion-photon mixing occurs due to a resonance in the atmosphere, and depending on the axion coupling strength and other parameters, significant axion-photon conversion can take place at the resonance. Such conversions may produce observable effects on the radiation spectra and polarization signals from the star. We also apply our results to axion-photon propagation in the Sun and in magnetic white dwarfs. We find that there is no appreciable conversion of solar axions to photons during the propagation.

Dong Lai; Jeremy Heyl

2006-09-28T23:59:59.000Z

470

Radiative Forcing of Climate Change  

SciTech Connect

Chapter 6 of the IPCC Third Assessment Report Climate Change 2001: The Scientific Basis. Sections include: Executive Summary 6.1 Radiative Forcing 6.2 Forcing-Response Relationship 6.3 Well-Mixed Greenhouse Gases 6.4 Stratospheric Ozone 6.5 Radiative Forcing By Tropospheric Ozone 6.6 Indirect Forcings due to Chemistry 6.7 The Direct Radiative Forcing of Tropospheric Aerosols 6.8 The Indirect Radiative Forcing of Tropospheric Aerosols 6.9 Stratospheric Aerosols 6.10 Land-use Change (Surface Albedo Effect) 6.11 Solar Forcing of Climate 6.12 Global Warming Potentials hydrocarbons 6.13 Global Mean Radiative Forcings 6.14 The Geographical Distribution of the Radiative Forcings 6.15 Time Evolution of Radiative Forcings Appendix 6.1 Elements of Radiative Forcing Concept References.

Ramaswamy, V.; Boucher, Olivier; Haigh, J.; Hauglustaine, D.; Haywood, J.; Myhre, G.; Nakajima, Takahito; Shi, Guangyu; Solomon, S.; Betts, Robert E.; Charlson, R.; Chuang, C. C.; Daniel, J. S.; Del Genio, Anthony D.; Feichter, J.; Fuglestvedt, J.; Forster, P. M.; Ghan, Steven J.; Jones, A.; Kiehl, J. T.; Koch, D.; Land, C.; Lean, J.; Lohmann, Ulrike; Minschwaner, K.; Penner, Joyce E.; Roberts, D. L.; Rodhe, H.; Roelofs, G.-J.; Rotstayn, Leon D.; Schneider, T. L.; Schumann, U.; Schwartz, Stephen E.; Schwartzkopf, M. D.; Shine, K. P.; Smith, Steven J.; Stevenson, D. S.; Stordal, F.; Tegen, I.; van Dorland, R.; Zhang, Y.; Srinivasan, J.; Joos, Fortunat

2001-10-01T23:59:59.000Z

471

Isocurvature perturbations in extra radiation  

E-Print Network (OSTI)

Recent cosmological observations, including measurements of the CMB anisotropy and the primordial helium abundance, indicate the existence of an extra radiation component in the Universe beyond the standard three neutrino species. In this paper we explore the possibility that the extra radiation has isocurvatrue fluctuations. A general formalism to evaluate isocurvature perturbations in the extra radiation is provided in the mixed inflaton-curvaton system, where the extra radiation is produced by the decay of both scalar fields. We also derive constraints on the abundance of the extra radiation and the amount of its isocurvature perturbation. Current observational data favors the existence of an extra radiation component, but does not indicate its having isocurvature perturbation. These constraints are applied to some particle physics motivated models. If future observations detect isocurvature perturbations in the extra radiation, it will give us a hint to the origin of the extra radiation.

Kawasaki, Masahiro; Nakayama, Kazunori; Sekiguchi, Toyokazu

2011-01-01T23:59:59.000Z

472

Stanford Synchrotron Radiation Lightsource  

NLE Websites -- All DOE Office Websites (Extended Search)

Beam Line 10-2 in parallel with magnetic resonance imaging (MRI) at Wayne State University to map and quantify iron and calcium on the same slices of human brain, thus...

473

X-ray Synchrotron Radiation in a Plasma Wiggler  

SciTech Connect

A relativistic electron beam can radiate due to its betatron motion inside an ion channel. The ion channel is induced by the electron bunch as it propagates through an underdense plasma. In the theory section of this thesis the formation of the ion channel, the trajectories of beam electrons inside the ion channel, the radiation power and the radiation spectrum of the spontaneous emission are studied. The comparison between different plasma wiggler schemes is made. The difficulties in realizing stimulated emission as the beam traverses the ion channel are investigated, with particular emphasis on the bunching mechanism, which is important for the ion channel free electron laser. This thesis reports an experiment conducted at the Stanford Linear Accelerator Center (SLAC) to measure the betatron X-ray radiations for the first time. They first describe the construction and characterization of the lithium plasma source. In the experiment, the transverse oscillations of the SLAC 28.5 GeV electron beam traversing through a 1.4 meter long lithium plasma source are clearly seen. These oscillations lead to a quadratic density dependence of the spontaneously emitted betatron X-ray radiation. The divergence angle of the X-ray radiation is measured. The absolute photon yield and the spectral brightness at 14.2 KeV photon energy are estimated and seen to be in reasonable agreement with theory.

Wang, Shuoquin; /UCLA /SLAC, SSRL

2005-09-27T23:59:59.000Z

474

Stored Program Computer as an Associative Radiation Analyzer  

Science Conference Proceedings (OSTI)

A system design based on the use of a stored program on?line computer is presented here. The system is used as an associative radiation analyzer. The channel capacity of the system is 20 bits (one million channel analyzer). The data storage program is based on a threaded list (tree) algorithm. The number of different events which will be measured during a particular experiment can be assigned for each experiment. The count capacity is 4096 counts per channel

Branko Sou?ek

1965-01-01T23:59:59.000Z

475

NREL: Solar Radiation Research - Capabilities  

NLE Websites -- All DOE Office Websites (Extended Search)

Capabilities NREL's solar radiation research staff provides expertise in renewable energy measurement and instrumentation. Major capabilities include solar resource measurement,...

476

Gamma radiation field intensity meter  

DOE Patents (OSTI)

A gamma radiation intensity meter measures dose rate of a radiation field. The gamma radiation intensity meter includes a tritium battery emitting beta rays generating a current which is essentially constant. Dose rate is correlated to an amount of movement of an electroscope element charged by the tritium battery. Ionizing radiation decreases the voltage at the element and causes movement. A bleed resistor is coupled between the electroscope support element or electrode and the ionization chamber wall electrode. 4 figs.

Thacker, L.H.

1994-08-16T23:59:59.000Z

477

Gamma radiation field intensity meter  

SciTech Connect

A gamma radiation intensity meter measures dose rate of a radiation field. The gamma radiation intensity meter includes a tritium battery emitting beta rays generating a current which is essentially constant. Dose rate is correlated to an amount of movement of an electroscope element charged by the tritium battery. Ionizing radiation decreases the voltage at the element and causes movement. A bleed resistor is coupled between the electroscope support element or electrode and the ionization chamber wall electrode.

Thacker, Louis H. (Knoxville, TN)

1995-01-01T23:59:59.000Z

478

Gamma radiation field intensity meter  

SciTech Connect

A gamma radiation intensity meter measures dose rate of a radiation field. The gamma radiation intensity meter includes a tritium battery emitting beta rays generating a current which is essentially constant. Dose rate is correlated to an amount of movement of an electroscope element charged by the tritium battery. Ionizing radiation decreases the voltage at the element and causes movement. A bleed resistor is coupled between the electroscope support element or electrode and the ionization chamber wall electrode.

Thacker, Louis H. (Knoxville, TN)

1994-01-01T23:59:59.000Z

479

Hybrid Radiator-Cooling System  

Technology Development & Commercialization Current Challenges Coolant radiators in highway trucks are designed to transfer maximum heat at a ...

480

Gamma radiation field intensity meter  

DOE Patents (OSTI)

A gamma radiation intensity meter measures dose rate of a radiation field. The gamma radiation intensity meter includes a tritium battery emitting beta rays generating a current which is essentially constant. Dose rate is correlated to an amount of movement of an electroscope element charged by the tritium battery. Ionizing radiation decreases the voltage at the element and causes movement. A bleed resistor is coupled between the electroscope support element or electrode and the ionization chamber wall electrode. 4 figs.

Thacker, L.H.

1995-10-17T23:59:59.000Z

Note: This page contains sample records for the topic "human radiation experiments" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.