Sample records for human health effects

  1. Clay minerals and their beneficial effects upon human health. M. Isabel Carretero*

    E-Print Network [OSTI]

    Ahmad, Sajjad

    Clay minerals and their beneficial effects upon human health. A review M. Isabel Carretero* Dpto examines the beneficial effects for human health of clay minerals, describing their use in pharmaceutical process and in its possible degradation effect. Among their uses in spas, clay minerals therapeutic

  2. Climate Change and Human Health National Center for Environmental Health

    E-Print Network [OSTI]

    Climate Change and Human Health National Center for Environmental Health Division of Environmental and Prevention October 17, 2012 #12;Coastal flooding Climate change effects: ·Temperature ·Sea level,civil conflict Anxiety,despair,depression Civil conflict Climate Change Health Effects Food & water Malnutrition

  3. COLLEGE OF ENGINEERING Human Health

    E-Print Network [OSTI]

    the exciting stories about how our faculty, students, and alumni are engineering solutions to health careCOLLEGE OF ENGINEERING Human Health #12;Welcome to our Health issue ­ Please take the time to read to tackle large worldwide health problems. A few years ago, the College of Engineering made a strategic

  4. Faculty of Science & Health SCHOOL OF HEALTH AND HUMAN PERFORMANCE

    E-Print Network [OSTI]

    Humphrys, Mark

    Faculty of Science & Health SCHOOL OF HEALTH AND HUMAN PERFORMANCE Teaching Fellowship in Athletic of Science and Health, the School of Health and Human Performance at DCU is developing an international reputation in health and exercise science. As such, the School of Health and Human Performance is committed

  5. Health effects of risk-assessment categories

    SciTech Connect (OSTI)

    Kramer, C.F.; Rybicka, K.; Knutson, A.; Morris, S.C.

    1983-10-01T23:59:59.000Z

    Environmental and occupational health effects associated with exposures to various chemicals are a subject of increasing concern. One recently developed methodology for assessing the health impacts of various chemical compounds involves the classification of similar chemicals into risk-assessment categories (RACs). This report reviews documented human health effects for a broad range of pollutants, classified by RACs. It complements other studies that have estimated human health effects by RAC based on analysis and extrapolation of data from animal research.

  6. DEPARTMENT OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH

    E-Print Network [OSTI]

    Levin, Judith G.

    ; and translating and disseminating research findings to health care providers, researchers, policymakersDCP - 1 DEPARTMENT OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH Drug Control Programs ..................................................................................................................................2 #12;DCP - 2 DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Resource Summary

  7. Communities: Human Health and Community Development Webinar ...

    Energy Savers [EERE]

    Communities: Human Health and Community Development Webinar Communities: Human Health and Community Development Webinar May 1, 2014 5:00PM to 6:30PM EDT The multi-agency...

  8. Faculty of Science & Health SCHOOL OF HEALTH AND HUMAN PERFORMANCE

    E-Print Network [OSTI]

    Humphrys, Mark

    Faculty of Science & Health SCHOOL OF HEALTH AND HUMAN PERFORMANCE Teaching Fellowship in Athletic Therapy (half time, 3 year contract) The School of Health and Human Performance invites applications from and assessment, have relevant qualifications and be experienced in emergency care training and be competent

  9. Human Health Science Building Geothermal Heat Pumps

    Broader source: Energy.gov (indexed) [DOE]

    HUMAN HEALTH SCIENCE BLDG GEO HEAT PUMP SYSTEMS Principal Investigator Source Heat Pumps Demo Projects May 20, 2010 This presentation does not contain any proprietary confidential,...

  10. Department of Health and Human Services Public Health Services

    E-Print Network [OSTI]

    Baker, Chris I.

    Department of Health and Human Services Public Health Services Review Group Type Activity Grant the obligation to comply with Public Health Services terms and conditions if a grant is awarded as a result/PI SUBTOTALS CONSULTANT COSTS EQUIPMENT (Itemize) SUPPLIES (Itemize by category) TRAVEL INPATIENT CARE COSTS

  11. PEOPLE OF CALIFORNIA HEALTH AND HUMAN

    E-Print Network [OSTI]

    Chair AIR RESOURCES BOARD Mary Nichols Chair DEPARTMENT OF HEALTH CARE SERVICES Toby Douglas DirectorPEOPLE OF CALIFORNIA HEALTH AND HUMAN SERVICES AGENCY Diana Dooley Secretary Michael Wilkening Deborah Raphael Director OFFICE OF ENVIRONMENTAL HEALTH HAZARD ASSESSMENT George Alexeeff Director

  12. Department of Health and Human Services National Institutes of Health

    E-Print Network [OSTI]

    Rau, Don C.

    , M.D. Technology Richard Nakamura., Ph.D. Andrea T. Norris #12;ES-3 FY 2015 Budget Request National 2015 Budget Page No. Organization ChartES-1 Department of Health and Human Services National Institutes of Health Executive Summary FY

  13. Health Effects Support Document for Hexachlorobutadiene Health Effects Support Document

    E-Print Network [OSTI]

    For Hexachlorobutadiene

    2003-01-01T23:59:59.000Z

    The Safe Drinking Water Act (SDWA), as amended in 1996, requires the Administrator of the Environmental Protection Agency (EPA) to establish a list of contaminants to aid the agency in regulatory priority setting for the drinking water program. In addition, SDWA requires EPA to make regulatory determinations for no fewer than five contaminants by August 2001. The criteria used to determine whether or not to regulate a chemical on the CCL are the following: The contaminant may have an adverse effect on the health of persons. The contaminant is known to occur or there is a substantial likelihood that the contaminant will occur in public water systems with a frequency and at levels of public health concern. In the sole judgment of the administrator, regulation of such contaminant presents a meaningful opportunity for health risk reduction for persons served by public water systems. The Agency’s findings for the three criteria are used in making a determination to regulate a contaminant. The Agency may determine that there is no need for regulation when a contaminant fails to meet one of the criteria. This document provides the health effects basis for the regulatory determination for hexachlorobutadiene. In arriving at the regulatory determination, data on toxicokinetics, human

  14. College of Human and Health Sciences

    E-Print Network [OSTI]

    Harman, Neal.A.

    8988 College of Human and Health Sciences All research is delivered through discipline-focused research centres, which examine fields such as child research, ageing, psychology and social care, as well as midwifery, nursing and allied health professions. External funding from a number of prestigious bodies has

  15. DEPARTMENT OF HEALTH &. HUMAN SERVICES Public Health Service National Institutes of Health

    E-Print Network [OSTI]

    Bandettini, Peter A.

    DEPARTMENT OF HEALTH &. HUMAN SERVICES Public Health Service National Institutes of Health of Intramural Research, OD Dr. James F. Taylor, Director Office ofAnimal Care and Use, OIR, OD Director, Division ofOccupational Health and Safety (DOHS) Scientific Resources, ORS Subject: Medical Surveillance of

  16. Global Warming and Human Health

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Science (SC) Environmental AssessmentsGeoffrey(SC) GettingGit GitGlobal Warming and Human

  17. Communication and Effectiveness in Primary Health Jean Carletta

    E-Print Network [OSTI]

    Carletta, Jean

    Communication and Effectiveness in Primary Health Care Teams Jean Carletta Human Communication.Carletta@edinburgh.ac.uk ABSTRACT Primary health care team members need to communicate effectively with each other in order of cross-disciplinary team meetings, we describe communication in primary health care teams, explore

  18. Human Health Science Building Geothermal Heat Pumps

    Broader source: Energy.gov [DOE]

    Project objectives: Construct a ground sourced heat pump, heating, ventilation, and air conditioning system for the new Oakland University Human Health Sciences Building utilizing variable refrigerant flow (VRF) heat pumps. A pair of dedicated outdoor air supply units will utilize a thermally regenerated desiccant dehumidification section. A large solar thermal system along with a natural gas backup boiler will provide the thermal regeneration energy.

  19. aeromonas human health: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    University of North Carolina at Charlotte, students and faculty help chart the course for health care Xie,Jiang (Linda) 10 Faculty of Science & Health SCHOOL OF HEALTH AND HUMAN...

  20. Estimated human health risks of disposing of nonhazardous oil field waste in salt caverns

    SciTech Connect (OSTI)

    Tomasko, D.; Elcock, D.; Veil, J.

    1997-09-01T23:59:59.000Z

    Argonne National Laboratory (ANL) has completed an evaluation of the possibility that adverse human health effects (carcinogenic and noncarcinogenic) could result from exposure to contaminants released from nonhazardous oil field wastes (NOW) disposed in domal salt caverns. In this assessment, several steps were used to evaluate potential human health risks: identifying potential contaminants of concern, determining how humans could be exposed to these contaminants, assessing the contaminants` toxicities, estimating contaminant intakes, and, finally, calculating human cancer and noncancer risks.

  1. Indoor air and human health revisited: A recent IAQ symposium

    SciTech Connect (OSTI)

    Gammage, R.B.

    1994-12-31T23:59:59.000Z

    Indoor Air and Human Health Revisited was a speciality symposium examining the scientific underpinnings of sensory and sensitivity effects, allergy and respiratory disease, neurotoxicity and cancer. An organizing committee selected four persons to chain the sessions and invite experts to give state-of-the-art presentations that will be published as a book. A summary of the presentations is made and some critical issues identified.

  2. Potential adverse health effects of wood smoke

    SciTech Connect (OSTI)

    Pierson, W.E.; Koenig, J.Q.; Bardana, E.J. Jr.

    1989-09-01T23:59:59.000Z

    The use of wood stoves has increased greatly in the past decade, causing concern in many communities about the health effects of wood smoke. Wood smoke is known to contain such compounds as carbon monoxide, nitrogen oxides, sulfur oxides, aldehydes, polycyclic aromatic hydrocarbons, and fine respirable particulate matter. All of these have been shown to cause deleterious physiologic responses in laboratory studies in humans. Some compounds found in wood smoke--benzo(a)pyrene and formaldehyde--are possible human carcinogens. Fine particulate matter has been associated with decreased pulmonary function in children and with increased chronic lung disease in Nepal, where exposure to very high amounts of wood smoke occurs in residences. Wood smoke fumes, taken from both outdoor and indoor samples, have shown mutagenic activity in short-term bioassay tests. Because of the potential health effects of wood smoke, exposure to this source of air pollution should be minimal.29 references.

  3. Human Health Risk & Environmental Analysis | Clean Energy | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    the interplay between human health and environmental risks associated with energy production, hazardous waste, national security and natural disasters. Research findings...

  4. Adjunct Faculty Data Request College of Health and Human Services

    E-Print Network [OSTI]

    Moore, Paul A.

    Adjunct Faculty Data Request College of Health and Human Services Bowling Green State University at Bowling Green State University are required to provide the following information. Appointments

  5. College of Health and Human Sciences School of Health Sciences

    E-Print Network [OSTI]

    Ginzel, Matthew

    : Environmental health and toxicology program formed 1970s: Industrial hygiene added 1979-Present: Era of School components of the School: Environmental Health Sciences, Radiological Health, and Industrial Hygiene (1963 with Tom Miya) Occupational health (industrial hygiene) (1979 with Dennis Paustenbach) Medical

  6. Human Resource Services Health Insurance Informational Session

    E-Print Network [OSTI]

    Karonis, Nicholas T.

    will be defaulted to the Quality Care Health Plan Enrollment forms were mailed by Central Management Services February 1, 2013 Preferred Provider Organization (PPO) Quality Care Health Plan (D3) Open Access Plan (OAP) ­ Managed Care Coventry OAP (CH) HealthLink OAP (CF) Health Maintenance Organization (HMO

  7. Department of Health and Human Services National Institutes of Health

    E-Print Network [OSTI]

    Rau, Don C.

    FY 2015 Budget Page No. Appropriation Language ...............................................................................................40 #12;OA-2 National Institutes of Health FY 2015 Congressional Justification FY 2015 Appropriations

  8. DEPARTMENT OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH

    E-Print Network [OSTI]

    Rau, Don C.

    ) Director, Research and Development Global Health, Population and Nutrition Contraceptive Technology and Gynecology Roy J. and Lucille A. Carver College of Medicine University of Iowa Health Care Iowa City, IA of Veterans Affairs Washington, DC 20420 LU, Michael C., M.D., M.P.H. Associate Administrator Maternal

  9. Department of Health and Human Services National Institutes of Health

    E-Print Network [OSTI]

    Rau, Don C.

    ,133.828 Drug Resources by Decision Unit National Institute on Drug Abuse 1 National Institute on Alcohol Abuse MISSION National Institute on Drug Abuse (NIDA) The societal impact of substance abuse (alcohol, tobacco a year in health care, crime-related, and productivity losses. To provide a comprehensive public health

  10. Department of Health and Human Services National Institutes of Health

    E-Print Network [OSTI]

    Rau, Don C.

    Resources by Decision Unit National Institute on Drug Abuse 1 National Institute on Alcohol Abuse Program Summary MISSION National Institute on Drug Abuse (NIDA) The societal impact of substance abuse $600 billion a year in health care, crime-related, and productivity losses. Knowledge is the foundation

  11. Health effects associated with energy conservation measures in commercial buildings

    SciTech Connect (OSTI)

    Stenner, R.D.; Baechler, M.C.

    1990-09-01T23:59:59.000Z

    Indoor air quality can be impacted by hundreds of different chemicals. More than 900 different organic compounds alone have been identified in indoor air. Health effects that could arise from exposure to individual pollutants or mixtures of pollutants cover the full range of acute and chronic effects, including largely reversible responses, such as rashes and irritations, to the irreversible toxic and carcinogenic effects. These indoor contaminants are emitted from a large variety of materials and substances that are widespread components of everyday life. Pacific Northwest Laboratory conducted a search of the peer-reviewed literature on health effects associated with indoor air contaminants for the Bonneville Power Administration to aid the agency in the preparation of environmental documents. Results are reported in two volumes. Volume 1 summarizes the results of the search of the peer-reviewed literature on health effects associated with a selected list of indoor air contaminants. In addition, the report discusses potential health effects of polychlorinated biphenyls and chlorofluorocarbons. All references to the literature reviewed are found in this document Volume 2. Volume 2 provides detailed information from the literature reviewed, summarizes potential health effects, reports health hazard ratings, and discusses quantitative estimates of carcinogenic risk in humans and animals. Contaminants discussed in this report are those that; have been measured in the indoor air of a public building; have been measured (significant concentrations) in test situations simulating indoor air quality (as presented in the referenced literature); and have a significant hazard rating. 38 refs., 7 figs., 23 tabs.

  12. Potential Health Effects of Marcellus Shale Activities: The Need for Public

    E-Print Network [OSTI]

    Sibille, Etienne

    . #12;Implications of the Gulf Oil Spill to Marcellus Shale Activities - Environmental and human health salt (Proprietary) 10.0 - 30.0% #12;Implications of the Gulf Oil Spill to Marcellus Shale ActivitiesPotential Health Effects of Marcellus Shale Activities: The Need for Public Health Surveillance

  13. Assessment Plans College of Education, Health and Human Development

    E-Print Network [OSTI]

    Dyer, Bill

    Program Plan Update LO Data Sched Education UG BS Early Childhood Education & Child Services Y 2014 Y Y YAssessment Plans 9/18/2014 College of Education, Health and Human Development Dept Level Degree Education UG BS Elementary Education K-8 Y 2014 Y Y N Education UG BS Secondary Education Y 2014 Y Y N

  14. Soil and human health: an epidemiological review R. L. HOUGH

    E-Print Network [OSTI]

    Ahmad, Sajjad

    Soil and human health: an epidemiological review R. L. HOUGH The Macaulay Institute, Craigiebuckler, Aberdeen AB15 8QH, UK Summary Two different approaches have been used to study relationships between soil in the geosciences and broadly relates spatial soil characteristics to geographic incidence of disease. However

  15. U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES

    E-Print Network [OSTI]

    Bandettini, Peter A.

    cells James McBride, Stephen Pennycook #12;Disease... Pollution... Hunger... Global warming... Did you on important health issues, including what causes certain diseases and how to treat them safely and effectively

  16. ('~ DEPARTMENT OF HEALTH & HUMAN SERVICES Public Health Service National Institutes of Health

    E-Print Network [OSTI]

    Baker, Chris I.

    and communicate research findings to patients and their families, health care providers, and the general public care professionals access to important health and science information from taxpayer to reach patients, health care providers, and our other audiences. While these communication efforts

  17. averted health effects: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    authors 18 Communication and Effectiveness in Primary Health CiteSeer Summary: Primary health care team members need to communicate effectively with each other in order to...

  18. Assessing human health risk in the USDA forest service

    SciTech Connect (OSTI)

    Hamel, D.R. [Department of Agriculture-Forest Service, Washington, DC (United States)

    1990-12-31T23:59:59.000Z

    This paper identifies the kinds of risk assessments being done by or for the US Department of Agriculture (USDA) Forest Service. Summaries of data sources currently in use and the pesticide risk assessments completed by the agency or its contractors are discussed. An overview is provided of the agency`s standard operating procedures for the conduct of toxicological, ecological, environmental fate, and human health risk assessments.

  19. Health effects of coal technologies: research needs

    SciTech Connect (OSTI)

    Not Available

    1980-09-01T23:59:59.000Z

    In this 1977 Environmental Message, President Carter directed the establishment of a joint program to identify the health and environmental problems associated with advanced energy technologies and to review the adequacy of present research programs. In response to the President's directive, representatives of three agencies formed the Federal Interagency Committee on the Health and Environmental Effects of Energy Technologies. This report was prepared by the Health Effects Working Group on Coal Technologies for the Committee. In this report, the major health-related problems associated with conventional coal mining, storage, transportation, and combustion, and with chemical coal cleaning, in situ gasification, fluidized bed combustion, magnetohydrodynamic combustion, cocombustion of coal-oil mixtures, and cocombustion of coal with municipal solid waste are identified. The report also contains recommended research required to address the identified problems.

  20. Submitted to the Journal of the American Water Resources Association Potential Human Health Effects Associated with Pathogens in Urban Wet Weather Flows

    E-Print Network [OSTI]

    Pitt, Robert E.

    Effects Associated with Pathogens in Urban Wet Weather Flows Robert Pitt1 , Melinda Lalor2 , and John stormwater conveyance systems, or wet weather sewage overflows, may adversely impact many of the desired uses. Urban runoff or wet weather flows include not only precipitation and washoff from lawns and landscaped

  1. Infrastructure, human resources, international cooperation, research and development, environment and health, societal issues, industrial innovation, Infrastructure, human resources, international cooperation, research and development, environment and hea

    E-Print Network [OSTI]

    Zürich, Universität

    Infrastructure, human resources, international cooperation, research and development, environment and health, societal issues, industrial innovation, Infrastructure, human resources, international Infrastructure, human resources, international cooperation, research and development, environment and health

  2. Adverse Health Effects of Air Pollution

    E-Print Network [OSTI]

    Haley, R. W.

    2011-01-01T23:59:59.000Z

    Adverse Health Effects of Air Pollution Robert W. Haley, M.D. Professor of Medicine Director, Division of Epidemiology University of Texas Southwestern Medical Center Dallas, Texas ? Texas Medical Association has adopted resolutions... Rice University study of how to maintain energy efficiency while reducing air pollution. ? Supported legislation based on the findings. The Medical Professor Increasingly Concerned ? Asthma ? Emphysema ? Heart Attacks ? Stunted lung...

  3. Evaluation of the Hazard of Microcystis Blooms for Human Health through Fish Consumption

    E-Print Network [OSTI]

    will be harmful to human health. #12;Proposed Work Microcystin Toxicokinetics Experiments Past experimentationEvaluation of the Hazard of Microcystis Blooms for Human Health through Fish Consumption Primary-Investigator: Duane Gossiaux - NOAA GLERL Overview Human exposure to the cyanobacterial toxin Microcystin occurs

  4. assessing human health: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Health Assessments Engineering Websites Summary: a next exam date recorded by the Student Health Care Center. Use this instruction guide to keep yourInstruction Guide Health...

  5. Health and utilization effects of expanding public health insurance

    E-Print Network [OSTI]

    Boyle, Melissa Ann

    2005-01-01T23:59:59.000Z

    This thesis exploits a major overhaul in the U.S. Department of Veterans Affairs health care system to answer various questions about publicly-provided health care. The VA restructuring involved the adoption of a capitated ...

  6. Effective Health Monitoring Strategies for Complex Structures /

    E-Print Network [OSTI]

    Haynes, Colin Michael

    2014-01-01T23:59:59.000Z

    to Optimization in Structural Health Monitoring, Proc. Worldaxioms of structural health monitoring, Proc. R. Soc. A.the future of structural health monitoring, Phil. Trans. R.

  7. U.S. Department of Health and Human Services National Institutes of Health NIH Division of Loan Repayment

    E-Print Network [OSTI]

    Bandettini, Peter A.

    Center The Year in Review 1 The Five Extramural Loan Repayment Programs 2 Applications, Awards of the NRSA Payback Service Center 18 The Year in Review 19 #12;U.S. Department of Health and Human Services

  8. HEALTH CARE REFORM AND ITS EFFECT ON STUDENT HEALTH PLANS INTRODUCTION

    E-Print Network [OSTI]

    Martinez, Tony R.

    TOPIC: HEALTH CARE REFORM AND ITS EFFECT ON STUDENT HEALTH PLANS INTRODUCTION: The Patient the initial impact of the Act on college and university- sponsored employee health care plans [1]. This Note-sponsored student health plans ("SHPs"). After the Affordable Care Act was enacted, many within the higher education

  9. Commentary Biodiesel Exhaust: The Need for Health Effects Research

    E-Print Network [OSTI]

    Kimberly J. Swanson; Michael C. Madden; Andrew J. Ghio

    2007-01-01T23:59:59.000Z

    BACKGROUND: Biodiesel is a diesel fuel alternative that has shown potential of becoming a commercially accepted part of the United States ’ energy infrastructure. In November 2004, the signing of the Jobs Creation Bill HR 4520 marked an important turning point for the future production of biodiesel in the United States because it offers a federal excise tax credit. By the end of 2005, industry production was 75 million gallons, a 300 % increase in 1 year. Current industry capacity, however, stands at just over 300 million gallons/year, and current expansion and new plant construction could double the industry’s capacity within a few years. Biodiesel exhaust emission has been extensively characterized under field and laboratory conditions, but there have been limited cytotoxicity and mutagenicity studies on the effects of biodiesel exhaust in biologic systems. OBJECTIVES: We reviewed pertinent medical literature and addressed recommendations on testing specific research needs in the field of biodiesel toxicity. DISCUSSION: Employment of biodiesel fuel is favorably viewed, and there are suggestions that its exhaust emissions are less likely to present any risk to human health relative to petroleum diesel emissions. CONCLUSION: The speculative nature of a reduction in health effects based on chemical composition of biodiesel exhaust needs to be followed up with investigations in biologic systems. KEY WORDS: air pollution, biodiesel, diesel exhaust, diesel fuels, lung diseases, vehicle emissions. Environ Health Perspect 115:496–499 (2007). doi:10.1289/ehp.9631 available via

  10. aerosols human health: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Health and Safety, was established, and is dedicated to providing outstanding clinical care to improve the health and safety of University employees 4 Adjoint model...

  11. ancillary human health: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Health and Safety, was established, and is dedicated to providing outstanding clinical care to improve the health and safety of University employees 4 Faculty of Science &...

  12. Geographically Differentiated Life-cycle Impact Assessment of Human Health

    E-Print Network [OSTI]

    Humbert, Sebastien

    2009-01-01T23:59:59.000Z

    indicators in life-cycle assessment (LCA). Human Ecologicalindicators in life-cycle assessment (LCA). Human EcologicalI explore how life-cycle assessment (LCA) results can

  13. Communications Assistant The College of Health and Human Sciences Dean's Office is seeking a dynamic individual to help us get

    E-Print Network [OSTI]

    of Communications College of Health and Human Sciences 226 L. L. Gibbons Building (970) 491-5182 | gretchen

  14. Human effects on the global atmosphere

    SciTech Connect (OSTI)

    Johnston, H.S.

    1984-01-01T23:59:59.000Z

    This review considers whether human activities can significantly change important functions of the global atmosphere by altering the amount or distribution of certain trace species. It deals with three specific topics: stratopheric ozone, the role of species other than carbon dioxide on the greenhouse effect, and certain recently recognized atmospheric consequences of a large scale nuclear war. 64 references, 10 figures, 2 tables.

  15. Health and environmental effects document for direct coal liquefaction - 1981.

    SciTech Connect (OSTI)

    Mellinger, P.J.; Wilson, B.W.; Mahlum, D.D.; Sever, L.E.; Olsen, A.R.

    1982-09-01T23:59:59.000Z

    This document presents initial estimates of potential human health effects from inhalation of nonmethane hydrocarbons (NMHC) that may be released from a future hypothetical industry producing about 600,000 bb1/day of synthetic fuel by direct liquefaction of coal. The assessment approach starts wth general assumptions that are then refined in a tiered sequence that considers available epidemiological, environmental and chemical data. The uncertainties involved in such an evaluation have been quantified where possible at this early stage of health risk analysis. Many surrogate data bases were considered for application to coal liquefaction including coke oven, British gas retort, roofing tar and asphalts, and cigarette smoke. The coke oven data base was selected for this assessment because the chemical and physical nature of coke oven emissions are judged to more closely approximate potential coal liquefaction emissions. Utilizing the extensive epidemiological data base for coke oven workers as a surrogate model, health effects from release of coal liquefaction NMHC may be quantified. This method results in estimates of about 1 x 10/sup -3/ excess cancer deaths/yr to an industrial work force of 7800 persons and 5 x 10/sup -2/ excess cancer deaths/yr in the U.S. population as a whole from NMHC that boil above 600/sup 0/F. Sources of uncertainty in the estimates are listed. Using these uncertainties, it is estimated that from 2 x 10/sup -4/ to 5 x 10/sup -3/ lung cancer deaths/yr may occur in the industrial work force and from 1 x 10/sup -2/ to 2.5 x 10/sup -1/ lung cancer deaths/yr in the U.S. population as a whole. On an individual basis, the excess lifetime risk to occupationally exposed workers is estimated to be 500 times greater than to members of the U.S. public.

  16. The coastal environment and human health: microbial indicators, pathogens, sentinels and reservoirs

    E-Print Network [OSTI]

    Polz, Martin F.

    Innovative research relating oceans and human health is advancing our understanding of disease-causing organisms in coastal ecosystems. Novel techniques are elucidating the loading, transport and fate of pathogens in coastal ...

  17. SUSTAINABILITY PRINCIPLES Harvard University is committed to developing and maintaining an environment that enhances human health

    E-Print Network [OSTI]

    Paulsson, Johan

    #12;#12;SUSTAINABILITY PRINCIPLES Harvard University is committed to developing and maintaining species. · · · Developing planning tools to enable comparative analysis of sustainability implications an environment that enhances human health and fosters a transition toward sustainability. Sustainability should

  18. Blood Pressure U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES

    E-Print Network [OSTI]

    Bandettini, Peter A.

    Your Blood Pressure Lowering Guide to U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Heart, Lung, and Blood Institute #12;Your Guide to Lowering Blood Pressure 2 What Are High Blood Pressure and Prehypertension? Blood pressure is the force of blood against

  19. Occupational Health Nurse

    Broader source: Energy.gov [DOE]

    The Occupational Health Nurse position is located in the Talent Sustainment group within the Human Capital Management (HCM) organization. The Talent Sustainment organization ensures that effective...

  20. Energy and Human Health Kirk R. Smith,1

    E-Print Network [OSTI]

    Mauzerall, Denise

    by Annual Reviews. All rights reserved Keywords coal, air pollution, biomass fuel, petroleum, nuclear energy accrue to the harvesting and burning of solid fuels, coal and biomass, mainly in the form of occupational health risks and household and general ambient air pollution. Lack of access to clean fuels

  1. EFFECTIVE STRUCTURAL HEALTH MONITORING WITH ADDITIVE MANUFACTURING

    E-Print Network [OSTI]

    Boyer, Edmond

    will be presented for components that can be processed by additive manufacturing (AM) or 3D printing. The origin structures. KEYWORDS : structural health monitoring methodology, 3D printing, additive manufacturing, fatigue, intelligent structure INTRODUCTION Additive manufacturing (AM), also known as 3D Printing or Rapid

  2. Non-Targeted Effects Induced by Ionizing Radiation: Mechanisms and Potential Impact on Radiation Induced Health Effects

    SciTech Connect (OSTI)

    Morgan, William F.; Sowa, Marianne B.

    2015-01-01T23:59:59.000Z

    Not-targeted effects represent a paradigm shift from the "DNA centric" view that ionizing radiation only elicits biological effects and subsequent health consequences as a result of an energy deposition event in the cell nucleus. While this is likely true at higher radiation doses (> 1Gy), at low doses (< 100mGy) non-targeted effects associated with radiation exposure might play a significant role. Here definitions of non-targeted effects are presented, the potential mechanisms for the communication of signals and signaling networks from irradiated cells/tissues are proposed, and the various effects of this intra- and intercellular signaling are described. We conclude with speculation on how these observations might lead to and impact long-term human health outcomes.

  3. adverse health effects: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    j.vaccine.2009.12.030 Expected and Unexpected adverse effects H1N1 vaccination for health care workers in a University Hospital CiteSeer Summary: All authors declare that...

  4. Human health benefits of ambient sulfate aerosol reductions under Title IV of the 1990 Clean Air Act amendments

    SciTech Connect (OSTI)

    Chestnut, L.G. [Hagler Bailly Consulting, Inc., Boulder, CO (United States); Watkins, A.M. [Environmental Protection Agency, Washington, DC (United States)

    1997-12-31T23:59:59.000Z

    The Acid Rain Provisions (Title IV) of the Clean Air Act Amendments of 1990 call for about a 10 million ton reduction in annual SO{sub 2} emissions in the United States by the year 2010. Although the provisions apply nationwide, most of the reduction will take place in the eastern half of the United States, where use of high sulfur coal for electricity generation is most common. One potentially large benefit of Title IV is the expected reduction in adverse human health effects associated with exposure to ambient sulfate aerosols, a secondary pollutant formed in the atmosphere when SO{sub 2} is present. Sulfate aerosols are a significant constituent of fine particulate (PM{sub 2.5}). This paper combines available epidemiologic evidence of health effects associated with sulfate aerosols and economic estimates of willingness to pay for reductions in risks or incidence of health effects with available estimates of the difference between expected ambient sulfate concentrations in the eastern United States and southeastern Canada with and without Title IV to estimate the expected health benefits of Title IV. The results suggest a mean annual benefit in the eastern United States of $10.6 billion (in 1994 dollars) in 1997 and $40.0 billion in 2010, with an additional $1 billion benefit each year in Ontario and Quebec provinces.

  5. Human Reliability Program (HRP) - HPMC Occupational Health Services

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville PowerCherries 82981-1cnHigh School football Highdefault SignInstituteDOE Origins ResourcesHuman

  6. addressing complex health: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    work is properly cited. This article considers some of the effects of health sector reform on human resources for health (HRH) in developing countries and countries in...

  7. M.S. in Health and Human Development Sustainable Food Systems Emphasis

    E-Print Network [OSTI]

    Dyer, Bill

    to promote health, human development, and well-being. The sustainable food systems program focuses://sites.google.com/site/friendsoflocalfood/ Sustainable Food and Bioenergy Systems Undergraduate Program: www.sfbs.montana.edu Accredited Dietetics completed a bachelor's degree in food and nutrition, agricultural science, environmental or food studies

  8. Abstract--Airborne pollution and explosive gases threaten human health and occupational safety, therefore generating high

    E-Print Network [OSTI]

    Mason, Andrew

    Abstract--Airborne pollution and explosive gases threaten human health and occupational safety and a thumb-drive sized prototype system. I. INTRODUCTION xposure to air pollution consistently ranks among to occupational safety as energy demands rise. Airborne pollutants and explosive gases vary in both time and space

  9. el equilibrio: U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES

    E-Print Network [OSTI]

    Baker, Chris I.

    National Cancer Institute Publicación de NIH, No. 05-5274 Junio 2005 Cómo las familias encuentran el Health and Human Development (Instituto Nacional de Salud Infantil y Desarrollo Humano, NICHD) y el National Cancer Institute (Instituto Nacional del Cáncer, NCI). ¡Podemos! es un programa único, puesto que

  10. COMPENSATION OF TEMPERATURE EFFECTS ON GUIDED WAVE BASED STRUCTURAL HEALTH MONITORING SYSTEMS

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    COMPENSATION OF TEMPERATURE EFFECTS ON GUIDED WAVE BASED STRUCTURAL HEALTH MONITORING SYSTEMS C strategy are investigated. KEYWORDS : Structural Health Monitoring (SHM), Guided Waves, Piezoelectric Sensors, Temperature Effects, Signal Processing. Introduction: STRUCTURAL HEALTH MONITORING

  11. Human health impacts for Renewable Energy scenarios from the EnerGEO Platform of Integrated Assessment (PIA)

    E-Print Network [OSTI]

    Boyer, Edmond

    Energy Agency with the use of the World En- ergy Model for the World Energy Outlook 2009, OrganizationHuman health impacts for Renewable Energy scenarios from the EnerGEO Platform of Integrated of renewable energy, affect concentrations of air pollutants and as a consequence affect human health. PM2

  12. EVALUATION OF EFFICACY AND HUMAN HEALTH RISK OF AERIAL ULTRA-LOW VOLUME APPLICATIONS OF PYRETHRINS AND

    E-Print Network [OSTI]

    Peterson, Robert K. D.

    EVALUATION OF EFFICACY AND HUMAN HEALTH RISK OF AERIAL ULTRA-LOW VOLUME APPLICATIONS OF PYRETHRINS). A human health risk assessment conducted by Peterson et al. (2006) for truck-mounted ultra-low volume (ULV to epidemic levels and dispersed to all 58 counties in the state, and was associated with low

  13. Risk assessment for the Waste Technologies Industries (WTI) hazardous waste incinerator facility (east Liverpool, Ohio). Volume 5. Human health risk assessment (HHRA): Evaluation of potential risks from multipathway exposure to emissions. Draft report

    SciTech Connect (OSTI)

    NONE

    1995-11-01T23:59:59.000Z

    The Human Health Risk Assessment (HHRA) portion of the WTI Risk Assessment involves the integration of information about the facility with site-specific data for the surrounding region and population to characterize the potential human health risks due to emissions from the facility. The estimation of human health risks is comprised of the following general steps: (1) identification of substances of potential concern; (2) estimation of the nature and magnitude of chemical releases from the WTI facility; (3) prediction of the atmospheric transport of the emitted contaminants; (4) determination of the types of adverse effects associated with exposure to the substances of potential concern (referred to as hazard identification), and the relationship between the level of exposure and the severity of any health effect (referred to as dose-response assessment); (5) estimation of the magnitude of exposure (referred to as exposure assessment); and (6) characterization of the health risks associated with exposure (referred to as risk characterization).

  14. Health effects of Halon 1301 exposure

    SciTech Connect (OSTI)

    Holness, D.L.; House, R.A. (Department of Occupational and Environmental Health, St Michael's Hospital, University of Toronto (Canada))

    1992-07-01T23:59:59.000Z

    An accidental discharge of a Halon 1301 system is reported. Thirty-one workers were assessed, 22 who were present at the time of the discharge, and 9 who worked the next shift. The incident was complicated by a small Freon-22 leak several hours later. Throat, eye, and nasal irritation and lightheadedness were reported by the majority of workers. Workers present during the halon discharge reported significantly more lightheadedness, headache, voice change, cough, and a fast heartbeat than did those who worked the later shift. These differences were significant even after correcting for confounding factors such as age, sex, and sense of anxiety at the time of the incident. The possible causes for the irritant symptoms include breakdown products of Halon 1301 and Freon-22 or contaminants from the halon discharge system. Although these irritant effects may not be an effect of Halon 1301 alone, they may occur in these discharge situations, and workers should be advised of this possibility. The possible cardiac and central nervous system effects also should be considered. The importance of a clear-cut protocol to deal with such incidents as well as worker education are discussed.

  15. Assessing Uncertainty in Spatial Exposure Models for Air Pollution Health Effects Assessment

    E-Print Network [OSTI]

    2007-01-01T23:59:59.000Z

    Spatial analysis of air pollution and mor- tality in Loslinking chronic air pollution exposure to health outcomes. J2006. Bayesian modeling of air pollution health effects with

  16. Long-term fate of depleted uranium at Aberdeen and Yuma Proving Grounds: Human health and ecological risk assessments

    SciTech Connect (OSTI)

    Ebinger, M.H.; Beckman, R.J.; Myers, O.B. [Los Alamos National Lab., NM (United States); Kennedy, P.L.; Clements, W.; Bestgen, H.T. [Colorado State Univ., Ft. Collins, CO (United States). Dept. of Fishery and Wildlife Biology

    1996-09-01T23:59:59.000Z

    The purpose of this study was to evaluate the immediate and long-term consequences of depleted uranium (DU) in the environment at Aberdeen Proving Ground (APG) and Yuma Proving Ground (YPG) for the Test and Evaluation Command (TECOM) of the US Army. Specifically, we examined the potential for adverse radiological and toxicological effects to humans and ecosystems caused by exposure to DU at both installations. We developed contaminant transport models of aquatic and terrestrial ecosystems at APG and terrestrial ecosystems at YPG to assess potential adverse effects from DU exposure. Sensitivity and uncertainty analyses of the initial models showed the portions of the models that most influenced predicted DU concentrations, and the results of the sensitivity analyses were fundamental tools in designing field sampling campaigns at both installations. Results of uranium (U) isotope analyses of field samples provided data to evaluate the source of U in the environment and the toxicological and radiological doses to different ecosystem components and to humans. Probabilistic doses were estimated from the field data, and DU was identified in several components of the food chain at APG and YPG. Dose estimates from APG data indicated that U or DU uptake was insufficient to cause adverse toxicological or radiological effects. Dose estimates from YPG data indicated that U or DU uptake is insufficient to cause radiological effects in ecosystem components or in humans, but toxicological effects in small mammals (e.g., kangaroo rats and pocket mice) may occur from U or DU ingestion. The results of this study were used to modify environmental radiation monitoring plans at APG and YPG to ensure collection of adequate data for ongoing ecological and human health risk assessments.

  17. Metals in Municipal Landfill Leachate And Their Health Effects

    E-Print Network [OSTI]

    Laughlin, Robert B.

    raw leachate contains concentrations of heavy metals in excess ofthe drinking water standards of the un- saturated zone. If municipal solid waste is placed di- rectly into ground water, or if leachateMetals in Municipal Landfill Leachate And Their Health Effects STEPHEN C. JAMES, BS, MSCE Abstract

  18. TEMPERATURE AND LOAD EFFECTS ON ACOUSTIC EMISSION SIGNALS FOR STRUCTURAL HEALTH MONITORING APPLICATIONS

    E-Print Network [OSTI]

    Boyer, Edmond

    TEMPERATURE AND LOAD EFFECTS ON ACOUSTIC EMISSION SIGNALS FOR STRUCTURAL HEALTH MONITORING. KEYWORDS : Structural Health Monitoring, Acoustic Emission, Environmental and Operational Conditions2014 Author manuscript, published in "EWSHM - 7th European Workshop on Structural Health Monitoring

  19. Health Risk Assessment: scale-dependent effects of urban air pollution on mortality

    E-Print Network [OSTI]

    Menut, Laurent

    Health Risk Assessment: scale-dependent effects of urban air pollution on mortality M. Valari(1), L;-Pollutants concentrations [c] ·Average outdoors pollution ·Indoors air quality ·Other sources of intoxication (food, water etc.) -Population exposure: [c] x dt -Health data & air pollution health effects Health

  20. Increased European biofuel cultivation could harm human health1 by James Morgan for www.scienceomega.com2

    E-Print Network [OSTI]

    South Bohemia, University of

    Increased European biofuel cultivation could harm human health1 by James Morgan for www that the large-scale production of biofuels in4 Europe could result in increased human mortality and crop losses that many biofuel plant species, including poplar and willow, release more isoprene ­ an6 ozone precursor

  1. VQ5. Ecosystem and Human Health How do changes in ecosystem composi9on and func9on

    E-Print Network [OSTI]

    Christian, Eric

    VQ5. Ecosystem and Human Health How do changes in ecosystem composi9on Issue: ·Ecosystem condition affects the humans dependent on those ecosystems for life and livelihood. How do changes in ecosystem composition and function correlate with famine, exposure to harmful biotic

  2. Risk assessment and toxicology databases for health effects assessment

    SciTech Connect (OSTI)

    Lu, P.Y.; Wassom, J.S. [Oak Ridge National Laboratory, TN (United States)

    1990-12-31T23:59:59.000Z

    Scientific and technological developments bring unprecedented stress to our environment. Society has to predict the results of potential health risks from technologically based actions that may have serious, far-reaching consequences. The potential for error in making such predictions or assessment is great and multiplies with the increasing size and complexity of the problem being studied. Because of this, the availability and use of reliable data is the key to any successful forecasting effort. Scientific research and development generate new data and information. Much of the scientific data being produced daily is stored in computers for subsequent analysis. This situation provides both an invaluable resource and an enormous challenge. With large amounts of government funds being devoted to health and environmental research programs and with maintenance of our living environment at stake, we must make maximum use of the resulting data to forecast and avert catastrophic effects. Along with the readily available. The most efficient means of obtaining the data necessary for assessing the health effects of chemicals is to utilize applications include the toxicology databases and information files developed at ORNL. To make most efficient use of the data/information that has already been prepared, attention and resources should be directed toward projects that meticulously evaluate the available data/information and create specialized peer-reviewed value-added databases. Such projects include the National Library of Medicine`s Hazardous Substances Data Bank, and the U.S. Air Force Installation Restoration Toxicology Guide. These and similar value-added toxicology databases were developed at ORNL and are being maintained and updated. These databases and supporting information files, as well as some data evaluation techniques are discussed in this paper with special focus on how they are used to assess potential health effects of environmental agents. 19 refs., 5 tabs.

  3. Identifying Requirements for Effective Human-Automation Teamwork

    SciTech Connect (OSTI)

    Jeffrey C. Joe; John O'Hara; Heather D. Medema; Johanna H. Oxstrand

    2014-06-01T23:59:59.000Z

    Previous studies have shown that poorly designed human-automation collaboration, such as poorly designed communication protocols, often leads to problems for the human operators, such as: lack of vigilance, complacency, and loss of skills. These problems often lead to suboptimal system performance. To address this situation, a considerable amount of research has been conducted to improve human-automation collaboration and to make automation function better as a “team player.” Much of this research is based on an understanding of what it means to be a good team player from the perspective of a human team. However, the research is often based on a simplified view of human teams and teamwork. In this study, we sought to better understand the capabilities and limitations of automation from the standpoint of human teams. We first examined human teams to identify the principles for effective teamwork. We next reviewed the research on integrating automation agents and human agents into mixed agent teams to identify the limitations of automation agents to conform to teamwork principles. This research resulted in insights that can lead to more effective human-automation collaboration by enabling a more realistic set of requirements to be developed based on the strengths and limitations of all agents.

  4. Appendix F Human Health Risk Assessment Document Number Q0029500 Appendix F

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOn AprilA groupTuba City, Arizona, DisposalFourthNrr-osams ADMIN RCD _WOMPOC:Human Health

  5. June 11, 2001 Investigation of Human Health Effects

    E-Print Network [OSTI]

    to Genetically Modified Corn A Report to the U.S. Food and Drug Administration from the Centers for Disease Associated with Potential Exposure to Genetically Modified Corn A Report to the U.S. Food and Drug of this investigation highlight the importance of evaluating the allergic potential of genetically modified foods before

  6. Waste management programmatic environmental impact statement methodology for estimating human health risks

    SciTech Connect (OSTI)

    Bergenback, B. [Midwest Technical, Inc. (United States); Blaylock, B.P.; Legg, J.L. [Oak Ridge National Lab., TN (United States)] [and others

    1995-05-01T23:59:59.000Z

    The US Department of Energy (DOE) has produced large quantities of radioactive and hazardous waste during years of nuclear weapons production. As a result, a large number of sites across the DOE Complex have become chemically and/or radiologically contaminated. In 1990, the Secretary of Energy charged the DOE Office of Environmental Restoration and Waste management (EM) with the task of preparing a Programmatic Environmental Impact Statement (PEIS). The PEIS should identify and assess the potential environmental impacts of implementing several integrated Environmental Restoration (ER) and Waste Management (WM) alternatives. The determination and integration of appropriate remediation activities and sound waste management practices is vital for ensuring the diminution of adverse human health impacts during site cleanup and waste management programs. This report documents the PEIS risk assessment methodology used to evaluate human health risks posed by WM activities. The methodology presents a programmatic cradle to grave risk assessment for EM program activities. A unit dose approach is used to estimate risks posed by WM activities and is the subject of this document.

  7. ASA conference on radiation and health: Health effects of electric and magnetic fields: Statistical support for research strategies. Final report

    SciTech Connect (OSTI)

    Not Available

    1990-05-01T23:59:59.000Z

    This report is a collection of papers documenting presentations made at the VIII ASA (American Statistical Association) Conference on Radiation and Health entitled Health Effects of Electric and Magnetic Fields: Statistical Support for Research Strategies. Individual papers are abstracted and indexed for the database.

  8. Effects of low levels of radiation on humans

    SciTech Connect (OSTI)

    Auxier, J.A.

    1981-01-01T23:59:59.000Z

    The state of knowledge on effects of low-level ionizing radiations on humans is reviewed. Several problems relating to dose thresholds or lack of thresholds for several types of cancer and high LET radiations and the effects of fractionation and dose protection are discussed. (ACR)

  9. Health and Environmental Effects Document on Geothermal Energy -- 1982 update

    SciTech Connect (OSTI)

    Layton, David W.; Daniels, Jeffrey I.; Anspaugh, Lynn R.; O'Banion, Kerry D.

    1983-11-30T23:59:59.000Z

    We assess several of the important health and environmental risks associated with a reference geothermal industry that produces 21,000 MWe for 30 y (equivalent to 20 x 10{sup 18} J). The analyses of health effects focus on the risks associated with exposure to hydrogen sulfide, particulate sulfate, benzene, mercury, and radon in air and arsenic in food. Results indicate that emissions of hydrogen sulfide are likely to cause odor-related problems in 29 of 51 geothermal resources areas, assuming that no pollution controls are employed. Our best estimates and ranges of uncertainty for the health risks of chronic population exposures to atmospheric pollutants are as follows (risks expressed per 10{sup 18} J of electricity): particulate sulfate, 44 premature deaths (uncertainty range of 0 to 360); benzene, 0.15 leukemias (range of 0 to 0.51); elemental mercury, 14 muscle tremors (range of 0 to 39); and radon, 0.68 lung cancers (range of 0 to 1.8). The ultimate risk of fatal skin cancers as the result of the transfer of waste arsenic to the general population over geologic time ({approx} 100,000 y) was calculated as 41 per 10{sup 18} J. We based our estimates of occupational health effects on rates of accidental deaths together with data on occupational diseases and injuries in surrogate industries. According to our best estimates, there would be 8 accidental deaths per 10{sup 18} J of electricity, 300 cases of occupational diseases per 10{sup 18} J, and 3400 occupational injuries per 10{sup 18}J. The analysis of the effects of noncondensing gases on vegetation showed that ambient concentrations of hydrogen sulfide and carbon dioxide are more likely to enhance rather than inhibit the growth of plants. We also studied the possible consequences of accidental releases of geothermal fluids and concluded that probably less than 5 ha of land would be affected by such releases during the production of 20 x 10{sup 18} J of electricity. Boron emitted from cooling towers in the Imperial Valley was identified as a potential source of crop damage. Our analyses, however, showed that such damage is unlikely. Finally, we examined the nonpollutant effects of land subsidence and induced seismicity. Land subsidence is possible around some facilities, but surface-related damage is not expected to be great. Induced seismic events that have occurred to date at geothermal resource areas have been nondestructive. It is not possible to predict accurately the risk of potentially destructive events, and more research is needed in this area.

  10. assessing health effects: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    the areas within the Health Care sector that can take 35 HTA Initiative 9 Local Health Technology Assessment: A Guide for Health Authorities CiteSeer Summary: management for...

  11. arsenic health effects: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Environmental Sciences and Ecology Websites Summary: HealthUC Berkeley, School of Public Health 12;WORLDWIDE ARSENIC EXPOSURE 12;Why Should You Care? 12ARSENIC IN...

  12. Human health and wellbeing in environmental impact assessment in New South Wales, Australia: Auditing health impacts within environmental assessments of major projects

    SciTech Connect (OSTI)

    Harris, Patrick J., E-mail: patrick.harris@unsw.edu.a [Centre for Health Equity Training, Research and Evaluation, part of the UNSW, Research Centre for Primary Health Care and Equity, UNSW, Locked Mail Bag 7103, Liverpool BC, NSW 1871 (Australia); Harris, Elizabeth, E-mail: e.harris@unsw.edu.a [Centre for Health Equity Training, Research and Evaluation, part of the UNSW, Research Centre for Primary Health Care and Equity, UNSW, Locked Mail Bag 7103, Liverpool BC, NSW 1871 (Australia); Thompson, Susan, E-mail: s.thompson@unsw.edu.a [Faculty of the Built Environment, UNSW, Sydney, NSW 2052 (Australia); Harris-Roxas, Ben, E-mail: b.harris-roxas@unsw.edu.a [Centre for Health Equity Training, Research and Evaluation, part of the UNSW, Research Centre for Primary Health Care and Equity, UNSW, Locked Mail Bag 7103, Liverpool BC, NSW 1871 (Australia); Kemp, Lynn, E-mail: l.kemp@unsw.edu.a [Centre for Health Equity Training, Research and Evaluation, part of the UNSW, Research Centre for Primary Health Care and Equity, UNSW, Locked Mail Bag 7103, Liverpool BC, NSW 1871 (Australia)

    2009-09-15T23:59:59.000Z

    Internationally the inclusion of health within environmental impact assessment (EIA) has been shown to be limited. While Australian EIA documentation has not been studied empirically to date, deficiencies in practice have been documented. This research developed an audit tool to undertake a qualitative descriptive analysis of 22 Major Project EAs in New South Wales, Australia. Results showed that health and wellbeing impacts were not considered explicitly. They were, however, included indirectly in the identification of traditional public health exposures associated with the physical environment and to a lesser extent the inclusion of social and economic impacts. However, no health data was used to inform any of the assessments, there was no reference to causal pathways between exposures or determinants and physical or mental health effects, and there was no inclusion of the differential distribution of exposures or health impacts on different populations. The results add conceptually and practically to the long standing integration debate, showing that health is in a position to add value to the EIA process as an explicit part of standard environmental, social and economic considerations. However, to overcome the consistently documented barriers to integrating health in EIA, capacity must be developed amongst EIA professionals, led by the health sector, to progress health related knowledge and tools.

  13. Effective science communication to children via a health-related Web site

    E-Print Network [OSTI]

    Gore, Sabra Ladd

    2004-09-30T23:59:59.000Z

    This study assesses one Web site, Veggie-mon.org. This Web site aims to effectively communciate health information to children, resulting in user learning and an intent to change health behavior. Fourth- through eighth-grade pupils were interviewed...

  14. WORKING PAPER N 2007 -40 The distortionary effect of health

    E-Print Network [OSTI]

    Boyer, Edmond

    , health care, public/private, compulsory/voluntary insurance PARIS-JOURDAN SCIENCES ECONOMIQUES for modeling the impact of insurance on health- care demand extending some of the results of the two-risk model and still consume healthcare. Keywords: Health insurance, Adverse selection, Health care, Public

  15. Health and environmental effects of oil and gas technologies: research needs

    SciTech Connect (OSTI)

    Brown, R. D.

    1981-07-01T23:59:59.000Z

    This report discusses health and environmental issues associated with oil and gas technologies as they are currently perceived - both those that exist and those that are expected to emerge over the next two decades. The various sections of this report contain discussions of specific problem areas and relevant new research activities which should be pursued. This is not an exhaustive investigation of all problem areas, but the report explores a wide range of issues to provide a comprehensive picture of existing uncertainties, trends, and other factors that should serve as the focus of future research. The problem areas of major concern include: effects of drilling fluids, offshore accidents, refineries and worker health, and biota and petroleum spills, indoor air pollution, information transfer, and unconventional resources. These are highlighted in the Executive Summary because they pose serious threats to human health and the environment, and because of the sparcity of accumulated knowledge related to their definition. Separate abstracts have been prepared for selected sections of this report for inclusion in the Energy Data Base. (DMC)

  16. Health effects models for nuclear power plant accident consequence analysis: Modifications of models resulting from recent reports on health effects of ionizing radiation

    SciTech Connect (OSTI)

    Abrahamson, S. (Wisconsin Univ., Madison, WI (United States)); Bender, M.A. (Brookhaven National Lab., Upton, NY (United States)); Boecker, B.B.; Scott, B.R. (Lovelace Biomedical and Environmental Research Inst., Albuquerque, NM (United States). Inhalation Toxicology Research Inst.); Gilbert, E.S. (Pacific Northwest Lab., Richland, WA (United States))

    1991-08-01T23:59:59.000Z

    The Nuclear Regulatory Commission has sponsored several studies to identify and quantify the potential health effects of accidental releases of radionuclides from nuclear power plants. The most recent health effects models resulting from these efforts were published in two reports, NUREG/CR-4214, Rev. 1, Part 1 (1990) and Part 2 (1989). Several major health effects reports have been published recently that may impact the health effects models presented in these reports. This addendum to the Part 2 (1989) report, provides a review of the 1986 and 1988 reports by the United Nations Scientific Committee on the Effects of Atomic Radiation, the National Academy of Sciences/National Research Council BEAR 5 Committee report and Publication 60 of the International Commission on Radiological Protection as they relate to this report. The three main sections of this addendum discuss early occurring and continuing effects, late somatic effects, and genetic effects. The major changes to the NUREG/CR-4214 health effects models recommended in this addendum are for late somatic effects. These changes reflect recent changes in cancer risk factors that have come from longer followup and revised dosimetry in major studies like that on the Japanese A-bomb survivors. The results presented in this addendum should be used with the basic NUREG/CR-4214 reports listed above to obtain the most recent views on the potential health effects of radionuclides released accidentally from nuclear power plants. 48 refs., 4 figs., 24 tabs.

  17. Effect of parental health beliefs and related dietary factors on adolescent health beliefs

    E-Print Network [OSTI]

    Madhavan, Meera

    1998-01-01T23:59:59.000Z

    Adolescent health beliefs of 54 adolescents residing phics. in Texas were compared with their parental health beliefs, parenting style, maternal diet related activities and eating habits, to determine their influence on willingness and perceived...

  18. Effect of parental health beliefs and related dietary factors on adolescent health beliefs 

    E-Print Network [OSTI]

    Madhavan, Meera

    1998-01-01T23:59:59.000Z

    Adolescent health beliefs of 54 adolescents residing phics. in Texas were compared with their parental health beliefs, parenting style, maternal diet related activities and eating habits, to determine their influence on ...

  19. Sustainable Material Selection of Toxic Chemicals in Design and Manufacturing From Human Health Impact Perspective

    E-Print Network [OSTI]

    Yuan, Chris; Dornfeld, David

    2009-01-01T23:59:59.000Z

    Human Toxicity Potential (HTP) method. Keywords: SustainableHuman Toxicity Potential (HTP) is used for the human healthassessment of toxic chemicals. HTP is a computed weighting

  20. Health effects model for nuclear power plant accident consequence analysis. Part I. Introduction, integration, and summary. Part II. Scientific basis for health effects models

    SciTech Connect (OSTI)

    Evans, J.S.; Moeller, D.W.; Cooper, D.W.

    1985-07-01T23:59:59.000Z

    Analysis of the radiological health effects of nuclear power plant accidents requires models for predicting early health effects, cancers and benign thyroid nodules, and genetic effects. Since the publication of the Reactor Safety Study, additional information on radiological health effects has become available. This report summarizes the efforts of a program designed to provide revised health effects models for nuclear power plant accident consequence modeling. The new models for early effects address four causes of mortality and nine categories of morbidity. The models for early effects are based upon two parameter Weibull functions. They permit evaluation of the influence of dose protraction and address the issue of variation in radiosensitivity among the population. The piecewise-linear dose-response models used in the Reactor Safety Study to predict cancers and thyroid nodules have been replaced by linear and linear-quadratic models. The new models reflect the most recently reported results of the follow-up of the survivors of the bombings of Hiroshima and Nagasaki and permit analysis of both morbidity and mortality. The new models for genetic effects allow prediction of genetic risks in each of the first five generations after an accident and include information on the relative severity of various classes of genetic effects. The uncertainty in modeloling radiological health risks is addressed by providing central, upper, and lower estimates of risks. An approach is outlined for summarizing the health consequences of nuclear power plant accidents. 298 refs., 9 figs., 49 tabs.

  1. Environmental and health effects review for obscurant graphite flakes. Final report, 1991 July--1993 May

    SciTech Connect (OSTI)

    Driver, C.J.; Ligotke, M.W.; Landis, W.G.; Downs, J.L.; Tiller, B.L.; Moore, E.B. Jr.; Cataldo, D.A.

    1993-07-01T23:59:59.000Z

    The health and environmental effects of obscurant graphite flakes were reviewed and compared to predicted levels of graphite flake material in the field during typical testing and training scenarios. Graphite flake dispersion and deposition for simulated mechanical and pyrotechnic releases were determined using a modified Gaussian atmospheric plume-dispersion model. The potential for wind resuspension of graphite flakes is controlled by weathering processes and incorporation rates in soil. Chemically, graphite flakes pose little risk to aquatic or terrestrial systems. Mechanical damage to plants and invertebrate and vertebrate organisms from the flakes is also minimal. In humans, the pathological and physiological response to inhaled graphite flake is similar to that induced by nuisance dusts and cause only transient pulmonary changes. Repeated exposure to very high concentrations (such as those near the source generator) may overwhelm the clearance mechanisms of the lung and result in pulmonary damage from the retained particles in unprotected individuals. However, these lesions either resolve with time or are of limited severity. Health effects of mixed aerosols of mixed aerosols of graphite and fog oil are similar to those produced by graphite flakes alone. Environmental impacts of fog oil-coated graphite flakes are not well known.

  2. Wind Turbines and Health A Rapid Review of the Evidence

    E-Print Network [OSTI]

    Firestone, Jeremy

    of the evidence from current literature on the issue of wind turbines and potential impacts on human health: There are no direct pathological effects from wind farms and that any potential impact on humans can be minimised regarding wind turbines and their potential effect on human health. It is important to note that these views

  3. FY 2008FY 2008FY 2012 U.S. Department of Health and Human Services National Institutes of Health

    E-Print Network [OSTI]

    Bandettini, Peter A.

    Table of Contents The Year in Review 1 The Four Intramural Loan Repayment Programs 2 Applications Institutes of Health The Year in Review In Fiscal Year (FY) 2012, 92 individuals applied to the Intramural

  4. FY 2008FY 2008FY 2010 U.S. Department of Health and Human Services National Institutes of Health

    E-Print Network [OSTI]

    Bandettini, Peter A.

    ­ National Institutes of Health NIH Intramural Loan Repayment Programs Table of Contents The Year in Review 1 Repayment Programs The Year in Review In Fiscal Year (FY) 2010, 96 individuals applied to the Intramural

  5. Schematic Characterization of Human Health Impact of Toxic Chemicals for Sustainable Design and Manufacturing

    E-Print Network [OSTI]

    Yuan, Chris Y.; Dornfeld, David

    2009-01-01T23:59:59.000Z

    Human Toxicity Potential (HTP) method. With an explicitHuman toxicity potential (HTP), proposed by Guinée andassessment of toxic chemicals. HTP is a computed weighting

  6. New Health Insurance Marketplace Coverage Options and Your Health Coverage Key parts of the Patient Protection and Affordable Care Act, also known as the health care reform law, go into effect January 1, 2014. When this

    E-Print Network [OSTI]

    Protection and Affordable Care Act, also known as the health care reform law, go into effect January 1, 2014 by the health care reform law (i.e., the plan's share of the total allowed benefit costs covered by the planNew Health Insurance Marketplace Coverage Options and Your Health Coverage Key parts of the Patient

  7. Global Health and Economic Impacts of Future Ozone Pollution

    E-Print Network [OSTI]

    Webster, Mort D.

    We assess the human health and economic impacts of projected 2000-2050 changes in ozone pollution using the MIT Emissions Prediction and Policy Analysis-Health Effects (EPPA-HE) model, in combination with results from the ...

  8. Contact the College of Human and Health Sciences for more information

    E-Print Network [OSTI]

    Martin, Ralph R.

    , doctors and other health and social care practitioners. This part-time provision extends to postgraduate be applied retrospectively to existing modules and programmes u Work closely with health and social care providers and professional bodies u Engage with employers across the health and social care, social policy

  9. acute health effects: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Placebo-controlled Trial; Christopher B. Harte; Cindy M. Meston 49 HEALTH CARE REFORM ORIGINAL INVESTIGATION One-Hour Rule-out and Rule-in of Acute Myocardial...

  10. Report on policy and activities concerning public awareness of health effects of low-level radiation

    SciTech Connect (OSTI)

    NONE

    1986-11-01T23:59:59.000Z

    In the summer of 1986, the Executive Committee authorized a study limited to determining policy and practices relevant to dissemination of information to the public on radiation health effects in three federal agencies. This report summarizes findings on two broad questions related to the communication issue: What, if any, are the policies under which federal agencies operate in disseminating information on health effects of radiation and what are the current programs and activities designed to provide the public information on health effects of radiation.

  11. Establishing Economic Effectiveness through Software Health-Management

    SciTech Connect (OSTI)

    Pizka, M; Panas, T

    2009-05-27T23:59:59.000Z

    More than two thirds of the annual software budget of large-scale organizations dealing with complex software systems is spent on the perfection, correction, and operation of existing software systems. A significant part of these running costs could be saved if the software systems that need to be constantly extende, maintained and operated were in a better technical condition. This paper proposes Software Health-Checks as a method to assess the technical condition of existing software systems and to deduce measures for improving the health of software in a structured manner. Since 2006 numerous commercial software systems with a total of 30 MLOC, implemented in various technologies, were already checked with this method. The actions suggested as a result of these Software 'Health-Checks', repeatedly yielded dramatic performance improvements, risk reductions and cost savings between 30% and 80%.

  12. To advance and share knowledge, discover solutions and promote opportunities in food and agriculture, bioenergy, health, the environment and human well-

    E-Print Network [OSTI]

    Sheridan, Jennifer

    and agriculture, bioenergy, health, the environment and human well- being. Vision: To lead in science, innovationMission: To advance and share knowledge, discover solutions and promote opportunities in food

  13. Health

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Science (SC) EnvironmentalGyroSolé(tm) Harmonicbet When yourecoveryG -Hazmat work opensHealth

  14. A Multidisciplinary Paradigm and Approach to Protecting Human Health and the Environment, Society, and Stakeholders at Nuclear Facilities - 12244

    SciTech Connect (OSTI)

    Burger, Joanna [Division of Life Sciences, Rutgers University, Piscataway, NJ (United States); Environmental and Occupational Health Sciences Institute, Piscataway, NJ (United States); Gochfeld, Michael [Consortium for Risk Evaluation with Stakeholder Participation (CRESP), Rutgers University, Piscataway NY, USA and Vanderbilt University, Nashville, TN (United States); Environmental and Occupational Medicine, UMDNJ-Robert Wood Johnson Medical School, Piscataway, NJ (United States); Clarke, James; Powers, Charles W.; Kosson, David [Consortium for Risk Evaluation with Stakeholder Participation (CRESP), Rutgers University, Piscataway NY, USA and Vanderbilt University, Nashville, TN (United States); Civil and Environmental Engineering, Vanderbilt University, Nashville, TN (United States)

    2012-07-01T23:59:59.000Z

    As the Department of Energy (DOE) continues to remediate its lands, and to consider moving toward long-term stewardship and the development of energy parks on its industrial, remediated land, it is essential to adequately characterize the environment around such facilities to protect society, human health, and the environment. While DOE sites re considering several different land-use scenarios, all of them require adequate protection of the environment. Even if DOE lands are developed for energy parks that are mainly for industrializes sections of DOE lands that will not be remediated to residential standards, there is still the need to consider the protection of human health and the environment. We present an approach to characterization and establishment of teams that will gather the information, and integrate that information for a full range of stakeholders from technical personnel, to public policy makers, and that public. Such information is needed to establish baselines, site new energy facilities in energy parks, protect existing nuclear facilities and nuclear wastes, improve the basis for emergency planning, devise suitable monitoring schemes to ensure continued protection, provide data to track local and regional response changes, and for mitigation, remediation and decommissioning planning. We suggest that there are five categories of information or data needs, including 1) geophysical, sources, fate and transport, 2) biological systems, 3) human health, 4) stakeholder and environmental justice, and 5) societal, economic, and political. These informational needs are more expansive than the traditional site characterization, but encompass a suite of physical, biological, and societal needs to protect all aspects of human health and the environment, not just physical health. We suggest a Site Committee be established that oversees technical teams for each of the major informational categories, with appropriate representation among teams and with a broad involvement of a range of governmental personnel, natural and social scientists, Native Americans, environmental justice communities, and other stakeholders. Such informational teams (and Oversight Committee) would report to a DOE-designated authority or Citizen's Advisory Board. Although designed for nuclear facilities and energy parks on DOE lands, the templates and information teams can be adapted for other hazardous facilities, such as a mercury storage facility at Oak Ridge. (authors)

  15. "Human Health Impact Characterization of Toxic Chemicals for Sustainable Design and Manufacturing

    E-Print Network [OSTI]

    Yuan, Chris; Dornfeld, David

    2009-01-01T23:59:59.000Z

    Human toxicity potential (HTP), proposed by Guinée andassessment of toxic chemicals. HTP is a computed weightingmodel environment [5]. The HTP values of toxic chemicals are

  16. Overview of ozone human exposure and health risk analyses used in the U.S. EPA's review of the ozone air quality standard.

    SciTech Connect (OSTI)

    Whitfield, R. G.

    1999-03-04T23:59:59.000Z

    This paper presents an overview of the ozone human exposure and health risk analyses developed under sponsorship of the U.S. Environmental Protection Agency (EPA). These analyses are being used in the current review of the national ambient air quality standards (NAAQS) for ozone. The analyses consist of three principal steps: (1) estimating short-term ozone exposure for particular populations (exposure model); (2) estimating population response to exposures or concentrations (exposure-response or concentration-response models); and (3) integrating concentrations or exposure with concentration-response or exposure-response models to produce overall risk estimates (risk model). The exposure model, called the probabilistic NAAQS exposure model for ozone (pNEM/03), incorporates the following factors: hourly ambient ozone concentrations; spatial distribution of concentrations; ventilation state of individuals at time of exposure; and movement of people through various microenvironments (e.g., outdoors, indoors, inside a vehicle) of varying air quality. Exposure estimates are represented by probability distributions. Exposure-response relationships have been developed for several respiratory symptom and lung function health effects, based on the results of controlled human exposure studies. These relationships also are probabilistic and reflect uncertainties associated with sample size and variability of response among subjects. The analyses also provide estimates of excess hospital admissions in the New York City area based on results from an epidemiology study. Overall risk results for selected health endpoints and recently analyzed air quality scenarios associated with alternative 8-hour NAAQS and the current 1-hour standard for outdoor children are used to illustrate application of the methodology.

  17. Direct and indirect effects of alpha-particle irradiations of human prostate tumor cells

    E-Print Network [OSTI]

    Wang, Rong, Ph. D. Massachusetts Institute of Technology

    2005-01-01T23:59:59.000Z

    The objective of this project is to establish a model system to study the direct effect, the bystander effect and the combinational effect of alpha-particle irradiations of human prostate tumor cells, toward the goal of ...

  18. Human-induced eutrophication enhances reproductive success through effects on parenting ability in sticklebacks

    E-Print Network [OSTI]

    Candolin, Ulrika

    Human-induced eutrophication enhances reproductive success through effects on parenting ability the effects of the ongoing eutrophication in the Baltic Sea on the reproductive success of threespine selection under changed environmental conditions, this suggests that the effect of eutrophication

  19. Screening Assessment of Potential Human-Health Risk from Future Natural-Gas Drilling Near Project Rulison in Western Colorado

    SciTech Connect (OSTI)

    Daniels Jeffrey I.,Chapman Jenny B.

    2012-01-01T23:59:59.000Z

    The Project Rulison underground nuclear test was conducted in 1969 at a depth of 8,400 ft in the Williams Fork Formation of the Piceance Basin, west-central Colorado (Figure 1). The U.S. Department of Energy Office of Legacy Management (LM) is the steward of the site. Their management is guided by data collected from past site investigations and current monitoring, and by the results of calculations of expected behavior of contaminants remaining in the deep subsurface. The purpose of this screening risk assessment is to evaluate possible health risks from current and future exposure to Rulison contaminants so the information can be factored into LM's stewardship decisions. For example, these risk assessment results can inform decisions regarding institutional controls at the site and appropriate monitoring of nearby natural-gas extraction activities. Specifically, the screening risk analysis can provide guidance for setting appropriate action levels for contaminant monitoring to ensure protection of human health.

  20. Effects of Extreme Sleep Deprivation on Human Performance

    SciTech Connect (OSTI)

    Tuan Tran; Kimberly R. Raddatz; Elizabeth T. Cady; Bradford Amstutz; Pete D. Elgin; Christopher Vowels; Gerald Deehan

    2007-04-01T23:59:59.000Z

    Sleep is a fundamental recuperative process for the nervous system. Disruption of this homeostatic drive can lead to severe impairments of the operator’s ability to perceive, recognize, and respond to emergencies and/or unanticipated events, putting the operator at risk. Therefore, establishing a comprehensive understanding of how sleep deprivation influences human performance is essential in order to counter fatigue or to develop mitigation strategies. The goal of the present study was to examine the psychological effects of prolonged sleep deprivation (approx. 75 hrs) over a four-day span on a general aviation pilot flying a fixed-based flight simulator. During the study, a series of tasks were employed every four hours in order to examine the pilot’s perceptual and higher level cognitive abilities. Overall, results suggest that the majority of cognitive and perceptual degradation occurs between 30-40 hours into the flight. Limitations and future research directions are also discussed.

  1. Water chlorination: environmental impact and health effects. Volume 3

    SciTech Connect (OSTI)

    Jolley, R.L.; Brungs, W.A.; Cumming, R.B. (eds.)

    1980-01-01T23:59:59.000Z

    The papers dealt with the major facets of chlorination and its associated effects. Each has been abstracted and indexed individually for ERA/EDB. (JGB)

  2. Health and environmental effects of coal-fired electric power plants

    SciTech Connect (OSTI)

    Morris, S.C.; Hamilton, L.D.

    1984-05-01T23:59:59.000Z

    This paper describes health and environmental impacts of coal-fired electric power plants. Effects on man, agriculture, and natural ecosystems are considered. These effects may result from direct impacts or exposures via air, water, and food chains. The paper is organized by geographical extent of effect. Occupational health impacts and local environmental effects such as noise and solid waste leachate are treated first. Then, regional effects of air pollution, including acid rain, are analyzed. Finally, potential global impacts are examined. Occupational health concerns considered include exposure to noise, dust, asbestos, mercury, and combustion products, and resulting injury and disease. Local effects considered include noise; air and water emissions of coal storage piles, solid waste operations, and cooling systems. Air pollution, once an acute local problem, is now a regional concern. Acute and chronic direct health effects are considered. Special attention is given to potential effects of radionuclides in coal and of acid rain. Finally, potential global impacts associated with carbon dioxide emissions are considered. 88 references, 9 tables.

  3. Turning quicksand into bedrock : understanding the dynamic effects of disease-focused global health aid on health systems

    E-Print Network [OSTI]

    Newkirk, Brian J

    2009-01-01T23:59:59.000Z

    This thesis asks one basic question: how do "vertical" disease- or intervention-focused global health programs impact the underlying health systems of the nations they serve? Vertical programs-health aid focused on a ...

  4. Effects of inhalable particles on respiratory health of children

    SciTech Connect (OSTI)

    Dockery, D.W.; Speizer, F.E.; Stram, D.O.; Ware, J.H.; Spengler, J.D.; Ferris, B.G. Jr.

    1989-03-01T23:59:59.000Z

    Results are presented from a second cross-sectional assessment of the association of air pollution with chronic respiratory health of children participating in the Six Cities Study of Air Pollution and Health. Air pollution measurements collected at quality-controlled monitoring stations included total suspended particulates (TSP), particulate matter less than 15 microns (PM15) and 2.5 microns (PM2.5) aerodynamic diameter, fine fraction aerosol sulfate (FSO4), SO2, O3, and No2. Reported rates of chronic cough, bronchitis, and chest illness during the 1980-1981 school year were positively associated with all measures of particulate pollution (TSP, PM15, PM2.5, and FSO4) and positively but less strongly associated with concentrations of two of the gases (SO2 and NO2). Frequency of earache also tended to be associated with particulate concentrations, but no associations were found with asthma, persistent wheeze, hay fever, or nonrespiratory illness. No associations were found between pollutant concentrations and any of the pulmonary function measures considered (FVC, FEV1, FEV0.75, and MMEF). Children with a history of wheeze or asthma had a much higher prevalence of respiratory symptoms, and there was some evidence that the association between air pollutant concentrations and symptom rates was stronger among children with these markers for hyperreactive airways. These data provide further evidence that rates of respiratory illnesses and symptoms are elevated among children living in cities with high particulate pollution. They also suggest that children with hyperreactive airways may be particularly susceptible to other respiratory symptoms when exposed to these pollutants.

  5. PA-40-201 1 Department of Health and Human Services

    E-Print Network [OSTI]

    Baker, Chris I.

    (s), Year(s), by 5:00 PM local time of applicant organization. AIDS Application Due Date(s) Standard AIDS Organization(s) National Institutes of Health (NIH) Components of Participating Organizations National Cancer Library of Medicine (NLM) Fogarty International Center (FIC) National Center for Complementary

  6. Social networks, social capital, and mental health While traditionally most studies of the effects of interpersonal relationships on health have focused primarily on social

    E-Print Network [OSTI]

    Banaji,. Murad

    Social networks, social capital, and mental health While traditionally most studies of the effects to explore the impact of the topology and dynamics of social networks on the development of health from person to person by travelling across the social networks in which people are socially embedded

  7. Patterns of health and disease have undergone dramatic transitions during human history, reflecting social and

    E-Print Network [OSTI]

    Vermont, University of

    of infectious disease and infant mortality decreased, lengthening life expectancy.At the same time,noninfectious chronic disease rose, accounting for a greater share of over- all mortality. Greater water and air dispersed into new habitats by phoresy (i.e.,one organism transporting another), flight, or wind, but human

  8. Approaches to advancing quantitative human health risk assessment of environmental chemicals in the post-genomic era

    SciTech Connect (OSTI)

    Chiu, Weihsueh A., E-mail: chiu.weihsueh@epa.gov [National Center for Environmental Assessment, U.S. Environmental Protection Agency, Washington DC, 20460 (United States); Euling, Susan Y.; Scott, Cheryl Siegel; Subramaniam, Ravi P. [National Center for Environmental Assessment, U.S. Environmental Protection Agency, Washington DC, 20460 (United States)

    2013-09-15T23:59:59.000Z

    The contribution of genomics and associated technologies to human health risk assessment for environmental chemicals has focused largely on elucidating mechanisms of toxicity, as discussed in other articles in this issue. However, there is interest in moving beyond hazard characterization to making more direct impacts on quantitative risk assessment (QRA) — i.e., the determination of toxicity values for setting exposure standards and cleanup values. We propose that the evolution of QRA of environmental chemicals in the post-genomic era will involve three, somewhat overlapping phases in which different types of approaches begin to mature. The initial focus (in Phase I) has been and continues to be on “augmentation” of weight of evidence — using genomic and related technologies qualitatively to increase the confidence in and scientific basis of the results of QRA. Efforts aimed towards “integration” of these data with traditional animal-based approaches, in particular quantitative predictors, or surrogates, for the in vivo toxicity data to which they have been anchored are just beginning to be explored now (in Phase II). In parallel, there is a recognized need for “expansion” of the use of established biomarkers of susceptibility or risk of human diseases and disorders for QRA, particularly for addressing the issues of cumulative assessment and population risk. Ultimately (in Phase III), substantial further advances could be realized by the development of novel molecular and pathway-based biomarkers and statistical and in silico models that build on anticipated progress in understanding the pathways of human diseases and disorders. Such efforts would facilitate a gradual “reorientation” of QRA towards approaches that more directly link environmental exposures to human outcomes.

  9. MERCURY EMISSIONS FROM COAL FIRED POWER PLANTS LOCAL IMPACTS ON HUMAN HEALTH RISK.

    SciTech Connect (OSTI)

    SULLIVAN, T.M.; BOWERMAN, B.; ADAMS, J.; LIPFERT, F.; MORRIS, S.M.; BANDO, A.; PENA, R.; BLAKE, R.

    2005-12-01T23:59:59.000Z

    A thorough quantitative understanding of the processes of mercury emissions, deposition, and translocation through the food chain is currently not available. Complex atmospheric chemistry and dispersion models are required to predict concentration and deposition contributions, and aquatic process models are required to predict effects on fish. However, there are uncertainties in all of these predictions. Therefore, the most reliable method of understanding impacts of coal-fired power plants on Hg deposition is from empirical data. A review of the literature on mercury deposition around sources including coal-fired power plants found studies covering local mercury concentrations in soil, vegetation, and animals (fish and cows). There is strong evidence of enhanced local deposition within 3 km of the chlor-alkali plants, with elevated soil concentrations and estimated deposition rates of 10 times background. For coal-fired power plants, the data show that atmospheric deposition of Hg may be slightly enhanced. On the scale of a few km, modeling suggests that wet deposition may be increased by a factor of two or three over background. The measured data suggest lower increases of 15% or less. The effects of coal-fired plants seem to be less than 10% of total deposition on a national scale, based on emissions and global modeling. The following summarizes our findings from published reports on the impacts of local deposition. In terms of excesses over background the following increments have been observed within a few km of the plant: (1) local soil concentration Hg increments of 30%-60%, (2) sediment increments of 18-30%, (3) wet deposition increments of 11-12%, and (4) fish Hg increments of about 5-6%, based on an empirical finding that fish concentrations are proportional to the square root of deposition. Important uncertainties include possible reductions of RGM to Hg{sub 0} in power plant plumes and the role of water chemistry in the relationship between Hg deposition and fish content. Soil and vegetation sampling programs were performed around two mid-size coal fired power plants. The objectives were to determine if local mercury hot-spots exist, to determine if they could be attributed to deposition of coal-fired power plant emissions, and to determine if they correlated with model predictions. These programs found the following: (1) At both sites, there was no correlation between modeled mercury deposition and either soil concentrations or vegetation concentrations. At the Kincaid plant, there was excess soil Hg along heavily traveled roads. The spatial pattern of soil mercury concentrations did not match the pattern of vegetation Hg concentrations at either plant. (2) At both sites, the subsurface (5-10 cm) samples the Hg concentration correlated strongly with the surface samples (0-5 cm). Average subsurface sample concentrations were slightly less than the surface samples; however, the difference was not statistically significant. (3) An unequivocal definition of background Hg was not possible at either site. Using various assumed background soil mercury concentrations, the percentage of mercury deposited within 10 km of the plant ranged between 1.4 and 8.5% of the RGM emissions. Based on computer modeling, Hg deposition was primarily RGM with much lower deposition from elemental mercury. Estimates of the percentage of total Hg deposition ranged between 0.3 and 1.7%. These small percentages of deposition are consistent with the empirical findings of only minor perturbations in environmental levels, as opposed to ''hot spots'', near the plants. The major objective of this study was to determine if there was evidence for ''hot-spots'' of mercury deposition around coal-fired power plants. Although the term has been used extensively, it has never been defined. From a public health perspective, such a ''hot spot'' must be large enough to insure that it did not occur by chance, and it must affect water bodies large enough to support a population of subsistence fishers. The results of this study support the hypothesis that n

  10. Effective Date: 04/03/2006 Environmental Health & Safety Tip Sheet

    E-Print Network [OSTI]

    Pawlowski, Wojtek

    Effective Date: 04/03/2006 Environmental Health & Safety Tip Sheet Lead-Acid Battery Charging Areas 11-02-06.doc http://www.ehs.cornell.edu/lrs/tipsheets.htm Page 1 of 2 Lead-Acid Battery Storage, Charging & Disposal Lead-acid batteries contain sulfuric acid (which is highly corrosive) and can generate

  11. Spatial analysis of health effects of large industrial incinerators in England,

    E-Print Network [OSTI]

    Diggle, Peter J.

    Spatial analysis of health effects of large industrial incinerators in England, 1998­2008: a study of large industrial incinerators in England, 1998­2008: a study using matched case­control areas. BMJ Open to industrial incinerators in England is associated with increased risk of cancer incidence and mortality

  12. THE LOCAL IMPACTS OF MERCURY EMISSIONS FROM COAL FIRED POWER PLANTS ON HUMAN HEALTH RISK. PROGRESS REPORT FOR THE PERIOD OF MARCH 2003 - MARCH 2003.

    SciTech Connect (OSTI)

    SULLIVAN,T.M.LIPFERT,F.D.MORRIS,S.M.

    2003-05-01T23:59:59.000Z

    This report presents a follow-up to previous assessments of the health risks of mercury that BNL performed for the Department of Energy. Methylmercury is an organic form of mercury that has been implicated as the form of mercury that impacts human health. A comprehensive risk assessment report was prepared (Lipfert et al., 1994) that led to several journal articles and conference presentations (Lipfert et al. 1994, 1995, 1996). In 2001, a risk assessment of mercury exposure from fish consumption was performed for 3 regions of the U.S (Northeast, Southeast, and Midwest) identified by the EPA as regions of higher impact from coal emissions (Sullivan, 2001). The risk assessment addressed the effects of in utero exposure to children through consumption of fish by their mothers. Two population groups (general population and subsistence fishers) were considered. Three mercury levels were considered in the analysis, current conditions based on measured data, and hypothetical reductions in Hg levels due to a 50% and 90% reduction in mercury emissions from coal fired power plants. The findings of the analysis suggested that a 90% reduction in coal-fired emissions would lead to a small reduction in risk to the general population (population risk reduction on the order of 10{sup -5}) and that the population risk is born by less than 1% of the population (i.e. high end fish consumers). The study conducted in 2001 focused on the health impacts arising from regional deposition patterns as determined by measured data and modeling. Health impacts were assessed on a regional scale accounting for potential percent reductions in mercury emissions from coal. However, quantitative assessment of local deposition near actual power plants has not been attempted. Generic assessments have been performed, but these are not representative of any single power plant. In this study, general background information on the mercury cycle, mercury emissions from coal plants, and risk assessment are provided to provide the basis for examining the impacts of local deposition. A section that covers modeling of local deposition of mercury emitted from coal power plants follows. The code ISCST3 was used with mercury emissions data from two power plants and local meteorological conditions to assess local deposition. The deposition modeling results were used to estimate the potential increase in mercury deposition that could occur in the vicinity of the plant. Increased deposition was assumed to lead to a linearly proportional increase in mercury concentrations in fish in local water bodies. Fish are the major pathway for human health impacts and the potential for increased mercury exposure was evaluated and the risks of such exposure estimated. Based on the findings recommendations for future work and conclusions are provided. Mercury is receiving substantial attention in a number of areas including: understanding of mercury deposition, bioaccumulation, and transport through the atmosphere, and improvements to the understanding of health impacts created by exposure to mercury. A literature review of key articles is presented as Appendix A.

  13. Human mouth microbes provide insight into health, disease | ornl.gov

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville PowerCherries 82981-1cnHigh School football Highdefault SignInstituteDOEMaterialsHuman

  14. The effect of European contact on the health of indigenous populations in Texas

    E-Print Network [OSTI]

    Miller, Elizabeth Ann

    1989-01-01T23:59:59.000Z

    ), and the prehistoric hunter/gatherer sites Blue Bayou (n-42) and Palm Harbor (n-7), were analyzed for medical disorders and dental attrition to determine the effect of European contact on indigenous populations in Texas. Mission San Juan Capistrano was active eight... PREHISTORIC SAMPLES 7 CARBOHYDRATE CONTENT. Page 63 67 . 83 84 85 86 92 LIST OF FIGURES FIGURE 1 TEXAS MAP SHOWING LOCATION OF SITES USED IN THIS ANALYSIS 2 THE HEALTH/DISEASE CONTINUUM 3 AN ECOLOGICAL APPROACH TO HEALTH AND DISEASE 4 TEXAS MAP...

  15. ORIGINAL PAPER Quantifying the effects of climate variability and human activities

    E-Print Network [OSTI]

    of the basin, and human activities. With the worsening of the water shortage problems and the increasing number do duty for a reference for regional water resources assessment and management. 1 Introduction of water-related disasters globally, the effects of climate variability and human activities on water

  16. Render me Real? Investigating the Effect of Render Style on the Perception of Animated Virtual Humans

    E-Print Network [OSTI]

    Render me Real? Investigating the Effect of Render Style on the Perception of Animated Virtual of lifelike virtual humans has been the goal of many movie makers in the last decade. Recently, films of psychophysical experiments to determine whether render style affects how virtual humans are perceived. Motion

  17. An analysis of uranium dispersal and health effects using a Gulf War case study.

    SciTech Connect (OSTI)

    Marshall, Albert Christian

    2005-07-01T23:59:59.000Z

    The study described in this report used mathematical modeling to estimate health risks from exposure to depleted uranium (DU) during the 1991 Gulf War for both U.S. troops and nearby Iraqi civilians. The analysis found that the risks of DU-induced leukemia or birth defects are far too small to result in an observable increase in these health effects among exposed veterans or Iraqi civilians. Only a few veterans in vehicles accidentally struck by U.S. DU munitions are predicted to have inhaled sufficient quantities of DU particulate to incur any significant health risk (i.e., the possibility of temporary kidney damage from the chemical toxicity of uranium and about a 1% chance of fatal lung cancer). The health risk to all downwind civilians is predicted to be extremely small. Recommendations for monitoring are made for certain exposed groups. Although the study found fairly large calculational uncertainties, the models developed and used are generally valid. The analysis was also used to assess potential uranium health hazards for workers in the weapons complex. No illnesses are projected for uranium workers following standard guidelines; nonetheless, some research suggests that more conservative guidelines should be considered.

  18. Critical review of the reactor-safety study radiological health effects model. Final report

    SciTech Connect (OSTI)

    Cooper, D.W.; Evans, J.S.; Jacob, N.; Kase, K.R.; Maletskos, C.J.; Robertson, J.B.; Smith, D.G.

    1983-03-01T23:59:59.000Z

    This review of the radiological health effects models originally presented in the Reactor Safety Study (RSS) and currently used by the US Nuclear Regulatory Commission (NRC) was undertaken to assist the NRC in determining whether or not to revise the models and to aid in the revision, if undertaken. The models as presented in the RSS and as implemented in the CRAC (Calculations of Reactor Accident Consequences) Code are described and critiqued. The major elements analyzed are those concerning dosimetry, early effects, and late effects. The published comments on the models are summarized, as are the important findings since the publication of the RSS.

  19. Computing the Effects of Operator Attention Allocation in Human Control of Multiple Robots

    E-Print Network [OSTI]

    Crandall, Jacob W.

    In time-critical systems in which a human operator supervises multiple semiautomated tasks, failure of the operator to focus attention on high-priority tasks in a timely manner can lower the effectiveness of the system and ...

  20. Human impacts on leaf economics in heterogeneous landscapes: the effect of harvesting non-timber forest

    E-Print Network [OSTI]

    Sack, Lawren

    Human impacts on leaf economics in heterogeneous landscapes: the effect of harvesting non tested the effect of foliage harvest by indigenous Fulani people on leaf stoichiometry and eco- nomics with world-wide trends in leaf economics. The effect of foliage harvest on foliar nutrient concentrations

  1. COM: A Method for Mining and Monitoring Human Activity Patterns in Home-based Health Monitoring Systems

    E-Print Network [OSTI]

    Cook, Diane J.

    for the health care system due to the shortage of health care professionals and health care facilities. To remedy population in the coming decades will result in many complications for families, society and the government, such as the shortage of health care professionals and care facilities, an increase in age related diseases and rising

  2. The Effect of Placement Change on Foster Children's Utilization of Emergency Mental Health Services

    E-Print Network [OSTI]

    Fawley-King, Kya

    2010-01-01T23:59:59.000Z

    Journal of Behavioral Health Services Research, 23(4), 389-Outpatient mental health services for children in fosteroutpatient mental health service use. Child Abuse and

  3. Combined methodology for estimating dose rates and health effects from exposure to radioactive pollutants

    SciTech Connect (OSTI)

    Dunning, D.E. Jr.; Leggett, R.W.; Yalcintas, M.G.

    1980-12-01T23:59:59.000Z

    The work described in the report is basically a synthesis of two previously existing computer codes: INREM II, developed at the Oak Ridge National Laboratory (ORNL); and CAIRD, developed by the Environmental Protection Agency (EPA). The INREM II code uses contemporary dosimetric methods to estimate doses to specified reference organs due to inhalation or ingestion of a radionuclide. The CAIRD code employs actuarial life tables to account for competing risks in estimating numbers of health effects resulting from exposure of a cohort to some incremental risk. The combined computer code, referred to as RADRISK, estimates numbers of health effects in a hypothetical cohort of 100,000 persons due to continuous lifetime inhalation or ingestion of a radionuclide. Also briefly discussed in this report is a method of estimating numbers of health effects in a hypothetical cohort due to continuous lifetime exposure to external radiation. This method employs the CAIRD methodology together with dose conversion factors generated by the computer code DOSFACTER, developed at ORNL; these dose conversion factors are used to estimate dose rates to persons due to radionuclides in the air or on the ground surface. The combination of the life table and dosimetric guidelines for the release of radioactive pollutants to the atmosphere, as required by the Clean Air Act Amendments of 1977.

  4. Space, light, and time : prospective analysis of Circadian illumination for health-based daylighting with applications to healthcare architecture

    E-Print Network [OSTI]

    Pechacek, Christopher S. (Christopher Scott)

    2008-01-01T23:59:59.000Z

    Light in architecture can be studied for its objective or perceptual effects. This thesis describes an objective link between human health and architectural design. Specifically, the link between daylight and human circadian ...

  5. THE INVESTIGATION OF CORROSION PROBLEMS, PRECAUTIONS AND THE NEW SYSTEMS REGARDING TO THE HUMAN HEALTH IN AUTOMOBILE INDUSTRY

    E-Print Network [OSTI]

    M. Evren Sar?yerli; Mercedes-benz Turk; Gökçe S. Sar?yerli

    In every part of our life and in every division of the industry, the corrosion is one of vital problems. It becomes a subject for research and progress in the automotive sector. Based on the knowledge that the lifetime is the most important insurance that is given to the customers by the firms in a though competition, the prevention of corrosion occurs depending on the environmental protection factors and the utilization of new technology. Necessary importance should be given to the human health and the production of vehicle according to the climate changes. On this study, primarily the types of corrosion in the automotive industry has been investigated and then the data of corrosion process and the protection concepts of corrosion have been given. Mostly the dynamic corrosion program and tests that have been applied to the test vehicle took place. And then the process of surface cathodic deep dying and the development of establishment have been mentioned. Lastly, the systems for the prevention of the corrosion with the environmental protection factor determined. The usage of test vehicle met with all the corrosion problems that normally do not happen, the region of corrosion can be easily determined and all the preventive precautions can be taken before corrosion occurs. Nowadays the advanced isolation techniques such as the phosphatising, the surface process, the cathodic deep dying, the coating of surface and the other protection concepts that realize the techniques to continue by the constructive application, the successful results on the surfaces of the vehicles have been taken.

  6. BASELINE PARAMETER UPDATE FOR HUMAN HEALTH INPUT AND TRANSFER FACTORS FOR RADIOLOGICAL PERFORMANCE ASSESSMENTS AT THE SAVANNAH RIVER SITE

    SciTech Connect (OSTI)

    Coffield, T; Patricia Lee, P

    2007-01-31T23:59:59.000Z

    The purpose of this report is to update parameters utilized in Human Health Exposure calculations and Bioaccumulation Transfer Factors utilized at SRS for Performance Assessment modeling. The reason for the update is to utilize more recent information issued, validate information currently used and correct minor inconsistencies between modeling efforts performed in SRS contiguous areas of the heavy industrialized central site usage areas called the General Separations Area (GSA). SRS parameters utilized were compared to a number of other DOE facilities and generic national/global references to establish relevance of the parameters selected and/or verify the regional differences of the southeast USA. The parameters selected were specifically chosen to be expected values along with identifying a range for these values versus the overly conservative specification of parameters for estimating an annual dose to the maximum exposed individual (MEI). The end uses are to establish a standardized source for these parameters that is up to date with existing data and maintain it via review of any future issued national references to evaluate the need for changes as new information is released. These reviews are to be added to this document by revision.

  7. Public meetings on radiation and its health effects caused by the Fukushima nuclear accident

    SciTech Connect (OSTI)

    Sugiyama, K.; Ayame, J.; Takashita, H.; Yamamoto, R. [Risk Communication Study Office Japan Atomic Energy Agency 4-33 Muramatsu, Tokai-mura, IBARAKI, 319-1194 (Japan)

    2013-07-01T23:59:59.000Z

    The Japan Atomic Energy Agency (JAEA) has held public meetings on radiation and its health effects mainly for parents of students in kindergartens, elementary schools, and junior high schools in Fukushima and Ibaraki prefectures after the Fukushima nuclear accident. These meetings are held based on our experience of practicing risk communication activities for a decade in JAEA with local residents. By analyzing questionnaires collected after the meetings, we confirmed that interactive communication is effective in increasing participants' understanding and in decreasing their anxiety. Most of the participants answered that they understood the contents and that it eased their mind. (authors)

  8. National Institutes of Health National Institute of Mental Health

    E-Print Network [OSTI]

    Baker, Chris I.

    National Institutes of Health National Institute of Mental Health Department of Health and HumanNational Institute of Mental Health Division of Intramural Research Programs http://intramural.nimh.nih.gov/ [NIMH of Fellowship Training] National Institutes of Health National Institute of Mental Health Department of Health

  9. Stressor Categories and Their Effects on Humans and Ecosystems

    E-Print Network [OSTI]

    Pitt, Robert E.

    ). Chapter 4 presents several case studies representing the major approaches to assessing receiving water ........................................................................................................................................92 EFFECTS OF RUNOFF ON RECEIVING WATERS Many studies have shown the severe detrimental effects of urban and agricultural runoff on receiving waters. These studies have generally examined receiving water

  10. Model Selection and Health Effect Estimation in Environmental Epidemiology Francesca Dominici, Chi Wang, Ciprian Crainiceanu, Giovanni Parmigiani

    E-Print Network [OSTI]

    Dominici, Francesca

    Abstract In air pollution epidemiology, improvements in statistical analysis tools can translate for confounding. In studies of air pollution and health, the focus should ideally be on estimating health effects estimate the association between prenatal and lifetime exposures to air pollutants and pulmonary function

  11. Environmental and health management in small and medium size enterprises

    E-Print Network [OSTI]

    Arredondo, Juan C. (Juan Carlos Arredondo Brun), 1974-

    2004-01-01T23:59:59.000Z

    Workers and employees are increasingly exposed in the workplace to chemical compounds and substances that are potentially toxic; for most of these compounds, no information exist regarding effects on human health. As one ...

  12. Effects of air pollution on the respiratory health of children: a cross-sectional study

    SciTech Connect (OSTI)

    Spinaci, S.; Arossa, W.; Bugiani, M.; Natale, P.; Bucca, C.; de Candussio, G.

    1985-09-01T23:59:59.000Z

    To investigate the effects of air pollution on the respiratory health of children, a subject of some controversy, a comparative study was undertaken of 2,385 school children who lived in central urban, peripheral urban, and suburban areas. Daily monitoring of sulfur dioxide and total suspended particle concentrations in all areas showed that pollutant concentrations in central and peripheral urban areas were above commonly accepted safety levels for respiratory health, while concentrations in the suburban area were within acceptable limits. A questionnaire administered to each mother assessed environmental exposure to pollutants in the household, the occurrence of respiratory symptoms as well as lung diseases as diagnosed by a physician, and general information. Children were interviewed about smoking habits and any acute respiratory symptoms. Children also performed standard lung function tests. Results showed that children from both urban areas had lessened pulmonary function and a higher prevalence of bronchial secretion with common colds than did those from the suburban area. These differences persisted after corrections for exposure to indoor pollutants, active or passive smoking, socioeconomic status, and sex. Parental cigarette smoking was related to a fall in forced expiratory volume in 1 second and an increased incidence of acute respiratory illnesses and chronic cough in children. Although boys had higher lung volumes and lower air flow, regression analysis showed no significant influence of the interactions sex-geographic area and sex-smoking on lung function. It was concluded that air pollution has a significant effect on the respiratory health of children.

  13. Effective sea-level rise and deltas: Causes of change and human dimension implications

    E-Print Network [OSTI]

    New Hampshire, University of

    Effective sea-level rise and deltas: Causes of change and human dimension implications Jason P January 2006 Abstract An assessment is made of contemporary effective sea-level rise (ESLR) for a sample of eustatic sea-level rise, the natural gross rate of fluvial sediment deposition and subsidence

  14. of Health Care National Institutes of Health

    E-Print Network [OSTI]

    Bandettini, Peter A.

    of Health Care National Institutes of Health Expanding Horizons Strategic Plan 2005-2009 UR nesmohsirh retir,ztnelinaoJ #12;of Health Care Expanding Horizons Strategic Plan 2005-2009 National Center.S Department of Health and Human Services National Center for Complementary and Alternative Medicine #12;A M mo

  15. Radiation therapy of pediatric brain tumors : comparison of long-term health effects and costs between proton therapy and IMRT

    E-Print Network [OSTI]

    Vu, An T. (An Thien)

    2011-01-01T23:59:59.000Z

    Radiation therapy is an important component of pediatric brain tumor treatment. However, radiation-induced damage can lead to adverse long-term health effects. Proton therapy has the ability to reduce the dose delivered ...

  16. The socioeconomic effects of uranium development in south Texas: a human ecological approach 

    E-Print Network [OSTI]

    Hopkins, Pamela Chris

    1982-01-01T23:59:59.000Z

    THE SOCIOECONOMIC FFFECTS OF URANIUM DEVELOPMENT IN SOUTH TEXAS: A HUMAN ECOLOGICAL APPROACH A Thesis by PAMELA CHRIS HOPKINS Submitted to tne Graduate College of Texas A&M University in partial fulfillment of the requirement for the degree... of MASTER OF SCIENCE August 1962 Major Subject: Sociology THE SOCIOECONOMIC EFFECTS OF URANIUM DEVELOPMENT IN SOUTH TEXAS: A HUMAN ECOLOGICAL APPROACH A Thesis by PAMELA CHRIS HOPKINS Approved as to style and content by: (Chairman of Committee...

  17. Effects of phenylpropanolamine (PPA) on in vitro human erythrocyte membranes and molecular models

    SciTech Connect (OSTI)

    Suwalsky, Mario, E-mail: msuwalsk@udec.cl [Faculty of Chemical Sciences, University of Concepcion, Concepcion (Chile)] [Faculty of Chemical Sciences, University of Concepcion, Concepcion (Chile); Zambrano, Pablo; Mennickent, Sigrid [Faculty of Pharmacy, University of Concepcion, Concepcion (Chile)] [Faculty of Pharmacy, University of Concepcion, Concepcion (Chile); Villena, Fernando [Faculty of Biological Sciences, University of Concepcion, Concepcion (Chile)] [Faculty of Biological Sciences, University of Concepcion, Concepcion (Chile); Sotomayor, Carlos P.; Aguilar, Luis F. [Instituto de Quimica, Pontificia Universidad Catolica de Valparaiso, Valparaiso (Chile)] [Instituto de Quimica, Pontificia Universidad Catolica de Valparaiso, Valparaiso (Chile); Bolognin, Silvia [CNR-Institute for Biomedical Technologies, University of Padova, Padova (Italy)] [CNR-Institute for Biomedical Technologies, University of Padova, Padova (Italy)

    2011-03-18T23:59:59.000Z

    Research highlights: {yields} PPA is a common ingredient in cough-cold medication and appetite suppressants. {yields} Reports on its effects on human erythrocytes are very scarce. {yields} We found that PPA induced in vitro morphological changes to human erythrocytes. {yields} PPA interacted with isolated unsealed human erythrocyte membranes. {yields} PPA interacted with class of lipid present in the erythrocyte membrane outer monolayer. -- Abstract: Norephedrine, also called phenylpropanolamine (PPA), is a synthetic form of the ephedrine alkaloid. After reports of the occurrence of intracranial hemorrhage and other adverse effects, including several deaths, PPA is no longer sold in USA and Canada. Despite the extensive information about PPA toxicity, reports on its effects on cell membranes are scarce. With the aim to better understand the molecular mechanisms of the interaction of PPA with cell membranes, ranges of concentrations were incubated with intact human erythrocytes, isolated unsealed human erythrocyte membranes (IUM), and molecular models of cell membranes. The latter consisted in bilayers built-up of dimyristoylphosphatidylcholine (DMPC) and dimyristoylphosphatidylethanolamine (DMPE), phospholipid classes present in the outer and inner monolayers of most plasmatic cell membranes, respectively. The capacity of PPA to perturb the bilayer structures of DMPC and DMPE was assessed by X-ray diffraction, DMPC large unilamellar vesicles (LUV) and IUM were studied by fluorescence spectroscopy, and intact human erythrocytes were observed by scanning electron microscopy (SEM). This study presents evidence that PPA affects human red cell membranes as follows: (a) in SEM studies on human erythrocytes it was observed that 0.5 mM PPA induced shape changes; (b) in IUM PPA induced a sharp decrease in the fluorescence anisotropy in the lipid bilayer acyl chains in a concentration range lower than 100 {mu}M; (c) X-ray diffraction studies showed that PPA in the 0.1-0.5 mM range induced increasing structural perturbation to DMPC, but no effects on DMPE multibilayers were detected.

  18. Using Science to Improve the Nation's Health System: NIH's Commitment to Comparative Effectiveness

    E-Print Network [OSTI]

    Bandettini, Peter A.

    and reform the US health care system. The National Institutes of Health (NIH) has been--and will continue; Health Policy; Medical Practice, Other; Quality of Care; Quality of Subscribe Email Alerts http health interventions yield the greatest benefits. Health reform and economic concerns may have moved

  19. Division of Human Resources Termination Of

    E-Print Network [OSTI]

    Meyers, Steven D.

    Division of Human Resources Termination Of Domestic Partnership Health Stipend Questions (813) 974 Insurance Stipend will terminate as of the Effective Date on this Termination of Domestic Partnership Health. ______ The Domestic Partnership Declaration attested to and filed by me with USF shall be and is terminated

  20. transforming human health

    E-Print Network [OSTI]

    Kenny, Paraic

    are in clinical trials: forodesine for treating leukemia and lymphoma, and BCX4208 for gout. Drugs to treat

  1. human health | EMSL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of strong brown carbon chromophores. Citation: Laskin J, A Laskin, S Nizkorodov, PJ Roach, PA Eckert, MK Gilles, B Wang, HJ Lee, and Q Hu.2014."Molecular Selectivity of Brown...

  2. EMSL - human health

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    MS) with high mass resolution (m&61636;m100,000). Solvent mixtures of acetonitrilewater and acetonitriletoluene were used to extract and ionize polar and non-polar...

  3. Irradiation Effects on Human Cortical Bone Fracture Behavior

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville PowerCherries 82981-1cnHigh SchoolIn12 Investigation Peer ReviewIron is the KeyIrradiation Effects

  4. Irradiation Effects on Human Cortical Bone Fracture Behavior

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville PowerCherries 82981-1cnHigh SchoolIn12 Investigation Peer ReviewIron is theIrradiation Effects on

  5. Western oil shale development: a technology assessment. Volume 8. Health effects of oil shale development

    SciTech Connect (OSTI)

    Rotariu, G.J.

    1982-02-01T23:59:59.000Z

    Information on the potential health effects of a developing oil shale industry can be derived from two major sources: (1) the historical experience in foreign countries that have had major industries; and (2) the health effects research that has been conducted in the US in recent years. The information presented here is divided into two major sections: one dealing with the experience in foreign countries and the second dealing with the more recent work associated with current oil shale development in the US. As a result of the study, several observations can be made: (1) most of the current and historical data from foreign countries relate to occupational hazards rather than to impacts on regional populations; (2) neither the historical evidence from other countries nor the results of current research have shown pulmonary neoplasia to be a major concern, however, certain types of exposure, particularly such mixed source exposures as dust/diesel or dust/organic-vapor have not been adequately studied and the lung cancer question is not closed; (3) the industry should be alert to the incidence of skin disease in the industrial setting, however, automated techniques, modern industrial hygiene practices and realistic personal hygiene should greatly reduce the hazards associated with skin contact; and (4) the entire question of regional water contamination and any resultant health hazard has not been adequately addressed. The industrial practice of hydrotreating the crude shale oil will diminish the carcinogenic hazard of the product, however, the quantitative reduction of biological activity is dependent on the degree of hydrotreatment. Both Soviet and American experimentalists have demonstrated a correlation betweed carcinogenicity/toxicity and retorting temperature; the higher temperatures producing the more carcinogenic or toxic products.

  6. Acute health effects of PM10 pollution on symptomatic and asymptomatic children

    SciTech Connect (OSTI)

    Pope, C.A. 3d.; Dockery, D.W. (Department of Economics, Brigham Young University, Provo, UT (United States))

    1992-05-01T23:59:59.000Z

    This study assessed the association between daily changes in respiratory health and respirable particulate pollution (PM10) in Utah Valley during the winter of 1990-1991. During the study period, 24-h PM10 concentrations ranged from 7 to 251 micrograms/m3. Participants included symptomatic and asymptomatic samples of fifth- and sixth-grade students. Relatively small but statistically significant (p less than 0.01) negative associations between peak expiratory flow (PEF) and PM10 were observed for both the symptomatic and asymptomatic samples. The association was strongest for the symptomatic children. Large associations between the incidence of respiratory symptoms, especially cough, and PM10 pollution were also observed for both samples. Again the association was strongest for the symptomatic sample. Immediate and delayed PM10 effects were observed. Respiratory symptoms and PEF changes were more closely associated with 5-day moving-average PM10 levels than with concurrent-day levels. These associations were also observed at PM10 levels below the 24-h standard of 150 micrograms/m3. This study indicates that both symptomatic and asymptomatic children may suffer acute health effects of respirable particulate pollution, with symptomatic children suffering the most.

  7. Evaluation of health effects in Sequoyah Fuels Corporation workers from accidental exposure to uranium hexafluoride

    SciTech Connect (OSTI)

    Fisher, D.R. (Pacific Northwest Lab., Richland, WA (USA)); Swint, M.J.; Kathren, R.L. (Hanford Environmental Health Foundation, Richland, WA (USA))

    1990-05-01T23:59:59.000Z

    Urine bioassay measurements for uranium and medical laboratory results were studied to determine whether there were any health effects from uranium intake among a group of 31 workers exposed to uranium hexafluoride (UF{sub 6}) and hydrolysis products following the accidental rupture of a 14-ton shipping cylinder in early 1986 at the Sequoyah Fuels Corporation uranium conversion facility in Gore, Oklahoma. Physiological indicators studied to detect kidney tissue damage included tests for urinary protein, casts and cells, blood, specific gravity, and urine pH, blood urea nitrogen, and blood creatinine. We concluded after reviewing two years of follow-up medical data that none of the 31 workers sustained any observable health effects from exposure to uranium. The early excretion of uranium in urine showed more rapid systemic uptake of uranium from the lung than is assumed using the International Commission on Radiological Protection (ICRP) Publication 30 and Publication 54 models. The urinary excretion data from these workers were used to develop an improved systemic recycling model for inhaled soluble uranium. We estimated initial intakes, clearance rates, kidney burdens, and resulting radiation doses to lungs, kidneys, and bone surfaces. 38 refs., 10 figs., 7 tabs.

  8. Probabilistic accident consequence uncertainty analysis -- Early health effects uncertainty assessment. Volume 2: Appendices

    SciTech Connect (OSTI)

    Haskin, F.E. [Univ. of New Mexico, Albuquerque, NM (United States); Harper, F.T. [Sandia National Labs., Albuquerque, NM (United States); Goossens, L.H.J.; Kraan, B.C.P. [Delft Univ. of Technology (Netherlands)

    1997-12-01T23:59:59.000Z

    The development of two new probabilistic accident consequence codes, MACCS and COSYMA, was completed in 1990. These codes estimate the consequence from the accidental releases of radiological material from hypothesized accidents at nuclear installations. In 1991, the US Nuclear Regulatory Commission and the Commission of the European Communities began cosponsoring a joint uncertainty analysis of the two codes. The ultimate objective of this joint effort was to systematically develop credible and traceable uncertainty distributions for the respective code input variables. A formal expert judgment elicitation and evaluation process was identified as the best technology available for developing a library of uncertainty distributions for these consequence parameters. This report focuses on the results of the study to develop distribution for variables related to the MACCS and COSYMA early health effects models. This volume contains appendices that include (1) a summary of the MACCS and COSYMA consequence codes, (2) the elicitation questionnaires and case structures, (3) the rationales and results for the panel on early health effects, (4) short biographies of the experts, and (5) the aggregated results of their responses.

  9. Roadmap: Integrated Health Studies Health Services Bachelor of Science

    E-Print Network [OSTI]

    Sheridan, Scott

    Six: [15 Credit Hours] NURS 45010 Health Care Policy and Delivery Systems or NURS 46000 Health CareRoadmap: Integrated Health Studies ­ Health Services ­ Bachelor of Science [EH-BS-IHS-HLSV] College of Education, Health, and Human Services School of Health Sciences Catalog Year: 2012­2013 Page 1 of 3 | Last

  10. LAND AND WATER USE CHARACTERISTICS AND HUMAN HEALTH INPUT PARAMETERS FOR USE IN ENVIRONMENTAL DOSIMETRY AND RISK ASSESSMENTS AT THE SAVANNAH RIVER SITE

    SciTech Connect (OSTI)

    Jannik, T.; Karapatakis, D.; Lee, P.; Farfan, E.

    2010-08-06T23:59:59.000Z

    Operations at the Savannah River Site (SRS) result in releases of small amounts of radioactive materials to the atmosphere and to the Savannah River. For regulatory compliance purposes, potential offsite radiological doses are estimated annually using computer models that follow U.S. Nuclear Regulatory Commission (NRC) Regulatory Guides. Within the regulatory guides, default values are provided for many of the dose model parameters but the use of site-specific values by the applicant is encouraged. A detailed survey of land and water use parameters was conducted in 1991 and is being updated here. These parameters include local characteristics of meat, milk and vegetable production; river recreational activities; and meat, milk and vegetable consumption rates as well as other human usage parameters required in the SRS dosimetry models. In addition, the preferred elemental bioaccumulation factors and transfer factors to be used in human health exposure calculations at SRS are documented. Based on comparisons to the 2009 SRS environmental compliance doses, the following effects are expected in future SRS compliance dose calculations: (1) Aquatic all-pathway maximally exposed individual doses may go up about 10 percent due to changes in the aquatic bioaccumulation factors; (2) Aquatic all-pathway collective doses may go up about 5 percent due to changes in the aquatic bioaccumulation factors that offset the reduction in average individual water consumption rates; (3) Irrigation pathway doses to the maximally exposed individual may go up about 40 percent due to increases in the element-specific transfer factors; (4) Irrigation pathway collective doses may go down about 50 percent due to changes in food productivity and production within the 50-mile radius of SRS; (5) Air pathway doses to the maximally exposed individual may go down about 10 percent due to the changes in food productivity in the SRS area and to the changes in element-specific transfer factors; and (6) Air pathway collective doses may go down about 30 percent mainly due to the decrease in the inhalation rate assumed for the average individual.

  11. Effects of Creep and Cyclic Loading on the Mechanical Properties and Failure of Human Achilles Tendons

    E-Print Network [OSTI]

    Stanford University

    underwent creep test- ing at constant stresses from 35 to 75 MPa. Another 25 tendons underwent sinusoidal slope of the force versus displacement curve for individual loading cycles.20,21 For the creep testsEffects of Creep and Cyclic Loading on the Mechanical Properties and Failure of Human Achilles

  12. Environmental Health Perspectives VOLUME 110 | NUMBER 12 | December 2002 1239 DDT and Its Metabolites Alter Gene Expression in Human Uterine Cell Lines

    E-Print Network [OSTI]

    McLachlan, John

    Environmental Health Perspectives · VOLUME 110 | NUMBER 12 | December 2002 1239 DDT and Its- trichloroethane (DDT) and its metabolites, have been shown to mimic estrogen, binding to and activating the ERs, thereby often pro- ducing estrogen-like effects (2,16­21). DDT and its metabolites have displayed harmful

  13. The impact and effectiveness of health impact assessment: A conceptual framework

    SciTech Connect (OSTI)

    Harris-Roxas, Ben, E-mail: ben@harrisroxashealth.com; Harris, Elizabeth, E-mail: e.harris@unsw.edu.au

    2013-09-15T23:59:59.000Z

    The use of health impact assessment (HIA) has expanded rapidly and there are increasing demands for it to demonstrate its effectiveness. This paper presents a conceptual framework for evaluating HIA and describes its development through (i) a review of the literature, (ii) a review of work undertaken as part of a major HIA capacity building project and (iii) an in-depth study of seven completed HIAs. The framework emphasises context, process and impacts as key domains in understanding and evaluating the effectiveness of an HIA. This new framework builds upon the existing approaches to evaluating HIA and extends them to reflect the broad range of factors that comprise and influence the effectiveness of HIAs. It may be of use in evaluating completed HIAs and in planning HIAs that are yet to be undertaken. -- Highlights: ? The first empirically-derived conceptual framework for evaluating HIA ? It may also be useful for planning and reporting on HIAs. ? The framework emphasises context, process and impacts as key domains. ? A broad range of factors influence the effectiveness of HIAs.

  14. Mountain Health Choices Beneficiary Report

    E-Print Network [OSTI]

    Mohaghegh, Shahab

    ................................................................................................................ 42 I. Access to Health Care Mountain Health Choices Beneficiary Report A Report to the West Virginia Bureau for Medical of Health and Human Resources, Bureau for Medical Services. #12; 1 Table of Contents I. EXECUTIVE

  15. 'Sifting the significance from the data' - the impact of high-throughput genomic technologies on human genetics and health care

    E-Print Network [OSTI]

    Clarke, Angus J; Cooper, David N; Krawczak, Michael; Tyler-Smith, Chris; Wallace, Helen M; Wilkie, Andrew O M; Raymond, Frances L; Chadwick, Ruth; Craddock, Nick; John, Ros; Gallacher, John; Chiano, Mathias

    2012-08-02T23:59:59.000Z

    the system of governance also serves other, more institutional purposes. The prospect of internet-based marketing corporations using access to research data and to electronic health records as an op- portunity to market more products seems both manipu- lative...

  16. Information resources for assessing health effects from chemical exposure: Challenges, priorities, and future issues

    SciTech Connect (OSTI)

    Seigel, S. [National Library of Medicine, Bethesda, MD (United States)

    1990-12-31T23:59:59.000Z

    Issues related to developing information resources for assessing the health effects from chemical exposure include the question of how to address the individual political issues relevant to identifying and determining the timeliness, scientific credibility, and completeness of such kinds of information resources. One of the important ways for agencies to share information is through connection tables. This type of software is presently being used to build information products for some DHHS agencies. One of the challenges will be to convince vendors of data of the importance of trying to make data files available to communities that need them. In the future, information processing will be conducted with neural networks, object-oriented database management systems, and fuzzy-set technologies, and meta analysis techniques.

  17. anthem.com/ca Anthem Blue Cross Life and Health Insurance Company (NP) M-LB2027 Effective 10/2010 Printed 6/1/2011 UCSD Medical Center

    E-Print Network [OSTI]

    Gleeson, Joseph G.

    federal health care reform laws. As we receive additional guidance and clarification on the new health care reform laws from the U.S. Department of Health and Human Services, Department of Labor and the California Department of Managed Health Care. In addition to dollar and percentage copays, members

  18. Environmental assessment for the satellite power system-concept development and evaluation program-microwave health and ecological effects

    SciTech Connect (OSTI)

    Not Available

    1980-11-01T23:59:59.000Z

    This report is concerned with the potential health and ecological effects of the microwave beam from the microwave power transmission system (MPTS) of the satellite power system (SPS). The report is written in the form of a detailed critical review of selected scientific articles from the published literature on the biological effects of nonionizing electromagnetic radiation, followed by an assessment of the possible effects of the SPS, based on exposure values for the reference system (US DOE and NASA, 1978).

  19. Manage the Margins: Three Essays on Effective Policymaking for Social Inequality in Health

    E-Print Network [OSTI]

    Zhu, Ling

    2011-10-21T23:59:59.000Z

    This dissertation includes three studies, devoted to trying to understand inequality in health between people from different social groups in a democratic society. In the U.S., social inequality in health takes various forms and the key...

  20. Race and gender differences in the effect of informal social supports on the use of health services by the elderly

    E-Print Network [OSTI]

    Nelson, Martha Alice

    1990-01-01T23:59:59.000Z

    RACE AND GENDER DIFFERENCES IN THE EFFECT OF INFORMAL SOCIAL SUPPORTS ON THE USE OF HEALTH SERVICES BY THE ELDERLY A Thesis by MARTHA ALICE NELSON Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment... of the requirements for the degree of MASTER OF SCIENCE December 1990 Major Subject: Sociology RACE AND GENDER DIFFERENCES IN THE EFFECT OF INFORMAL SOCIAL SUPPORTS ON THE USE OF HEALTH SERVICES BY THE ELDERLY A Thesis by MARTHA ALICE NELSON Approved...

  1. Programs director`s report for the Office of Health and Environmental Research

    SciTech Connect (OSTI)

    NONE

    1996-08-01T23:59:59.000Z

    Since its establishment, the Department of Energy`s Office of Health and Environmental Research (OHER) has had responsibility for conducting biological research to develop the knowledge needed to identify, understand, and anticipate the long-term health consequences of energy use and development, including the potential health impacts of radiation. The Health Effects Research Program has established the basis for understanding the health consequences of radiation for humans, developed radiation dosimetry methodology, characterized and evaluated the health impacts of fossil fuels, and developed and conducted research to determine the health impacts of inhaled toxicants. The results of this research have provided input for setting genetic standards for radiation and chemical exposure.

  2. Study downplays health concerns

    SciTech Connect (OSTI)

    Stringer, J.

    1996-03-13T23:59:59.000Z

    A government-funded study has concluded that reformulated gasoline containing methyl tert-butyl ether (MTBE) does not increase short-term health risks when compared with gasoline that does not contain the additive. The study, performed by the Health Effects Institute (Cambridge, MA), compared data from dozens of animal, human, and epidemiological studies of health effects linked to oxygenates, including MTBE and ethanol, but did not find enough evidence to warrant an immediate reduction in oxygenate use. However, the study did recommend that additional research be conducted on possible health consequences associated with the gasoline additives, including neurotoxic effects, if oxygenates continue to be used long term. Oxygenates have been used in gasoline since 1992, when EPA mandated that several municipalities use MTBE or other oxygenates in reformulated gasoline to reduce carbon monoxide emissions and meet Clean Air Act requirements. Shortly after the program began, residents in areas where the oxygenates were used complained of nausea, headaches, and dizziness. The institute says the study--funded by EPA and the Centers for Disease Control--will be used for a broader review of gasoline oxygenates by the White House Office of Science and Technology Policy.

  3. The effect of human alpha interferon on experimentally induced equine herpesvirus-1 infection in horses

    E-Print Network [OSTI]

    Seahorn, Thomas Leon

    1989-01-01T23:59:59.000Z

    weight gains and improved feed efficiency. These studies in cattle used interferon at much lower dosages than currently used in humans. Also, studies in cats infected with feline leukemia virus have shown extended lifespans and regenerative responses... that interferon is effective at much lower dosages than previously recognized. Also, studies in cats infected with feline leukemia virus have shown extended lifespans and regenerative responses to anemia following oral administration of interferon. 3i Other...

  4. Health effects of acid aerosols on North American children: Respiratory symptoms

    SciTech Connect (OSTI)

    Dockery, D.W. [Harvard School of Public Health, Boston, MA (United States)]|[Channing Lab., Boston, MA (United States); Cunningham, J.; Damokosh, A.I. [Harvard School of Public Health, Boston, MA (United States)] [and others

    1996-05-01T23:59:59.000Z

    We examined the respiratory health effects of exposure to acidic air pollution among 13,369 white children 8 to 12 years old from 24 communities in the United States and Canada between 1988 and 1991. Each child`s parent or guardian completed a questionnaire. Air quality and meteorology were measured in each community for a 1-year period. We used a two-stage logistic regression model to analyze the data, adjusting for the period confounding effects of sex, history of allergies, parental asthma, parental education, and current smoking in the home. Children living in the community with the highest levels of particle strong acidity were significantly more likely [odds ratio (OR) = 1.66; 95% confidence interval (CI) 1.11-2.48] to report at least one episode of bronchitis in the past year compared to children living in the least-polluted community. Fine particulate sulfate was also associated with higher reporting of bronchitis (OR = 1.65; 95% CI 1.12-2.42). No other respiratory symptoms were significantly higher in association with any of the air pollutants of interest. No sensitive subgroups were identified. Reported bronchitis, but neither asthma, wheeze, cough, nor phlegm, were associated with levels of particle strong acidity for these children living in a nonurban environment. 26 refs., 3 figs., 4 tabs.

  5. assessing health risks: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    to Human Health Risk Assessment CPH 418518 Biology and Medicine Websites Summary: SYLLABUS Introduction to Human Health Risk Assessment CPH 418518 SWES 418518 Time: Tuesday...

  6. assess health risks: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    to Human Health Risk Assessment CPH 418518 Biology and Medicine Websites Summary: SYLLABUS Introduction to Human Health Risk Assessment CPH 418518 SWES 418518 Time: Tuesday...

  7. Health Information Systems for Primary Health Care: Thinking About Participation

    E-Print Network [OSTI]

    Sahay, Sundeep

    Health Information Systems for Primary Health Care: Thinking About Participation Elaine Byrne in supporting primary health care functioning, the design, development and implementation of these systems information systems, human rights 1. Introduction: Primary health care is a crucial element of national health

  8. Annu. Rev. Public Health 2004. 25:24780 doi: 10.1146/annurev.publhealth.25.102802.124329

    E-Print Network [OSTI]

    Dominici, Francesca

    .edu, jsamet@jhsph.edu, fdominic@jhsph.edu Key Words air pollution, public health, epidemiology, regression models s Abstract Studies of air pollution and human health have evolved from descriptive studies of the early phenomena of large increases in adverse health effects following extreme air pollution episodes

  9. Quantifying the health and economic impacts of mercury : an integrated assessment approach

    E-Print Network [OSTI]

    Giang, Amanda (Amanda Chi Wen)

    2013-01-01T23:59:59.000Z

    Mercury is a toxic pollutant that endangers human and ecosystem health. Especially potent in the form of methyl mercury, exposure is known to lead to adverse neurological effects, and, a growing body of evidence suggests, ...

  10. Emergency Response Health Physics

    SciTech Connect (OSTI)

    Mena, RaJah [National Security Technologies, LLC, Remote Sensing Laboratory–Nellis; Pemberton, Wendy [National Security Technologies, LLC, Remote Sensing Laboratory–Nellis; Beal, William [Remote Sensing Laboratory at Andrews

    2012-05-01T23:59:59.000Z

    Health physics is an important discipline with regard to understanding the effects of radiation on human health; however, there are major differences between health physics for research or occupational safety and health physics during a large-scale radiological emergency. The deployment of a U.S. Department of Energy/National Nuclear Security Administration (DOE/NNSA) monitoring and assessment team to Japan in the wake of the March 2011 accident at Fukushima Daiichi Nuclear Power Plant yielded a wealth of lessons on these difference. Critical teams (CMOC (Consequence Management Outside the Continental U.S.) and CMHT (Consequence Management Home Team) ) worked together to collect, compile, review, and analyze radiological data from Japan to support the response needs of and answer questions from the Government of Japan, the U.S. military in Japan, the U.S. Embassy and U.S. citizens in Japan, and U.S. citizens in America. This paper addresses the unique challenges presented to the health physicist or analyst of radiological data in a large-scale emergency. A key lesson learned was that public perception and the availability of technology with social media requires a diligent effort to keep the public informed of the science behind the decisions in a manner that is meaningful to them.

  11. Human Pathogen Importation Importing "Human" Pathogens from Outside Canada

    E-Print Network [OSTI]

    Human Pathogen Importation Importing "Human" Pathogens from Outside Canada 1) Permits be obtained from the Public Health Agency Canada (PHAC) to facilitate customs clearance. 2) If a permit

  12. E-Print Network 3.0 - animal health effects Sample Search Results

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biology and Medicine ; Environmental Sciences and Ecology 2 Policy on the Occupational Health & Safety Program in the Care and Use of Animals in Research and Instruction...

  13. Tropical Medicine and International Health voLUME 2 NO rr SUPPLEMENT PP Ar-A54 NOVEMBER 1997 Human behaviour and cultural context in disease control

    E-Print Network [OSTI]

    /faith in rural health care. Utilization rates are often low in rural clinics because health care wor

  14. Parental involvement in mental health services for diverse youth

    E-Print Network [OSTI]

    Liang, June

    2010-01-01T23:59:59.000Z

    M. (2002). Mental health services for Latino adolescentsfamilies to mental health services: The role of the familyoutpatient mental health services. New York: Human Sciences

  15. HEI/CDC/EPA Workshop on Tracking Air Pollution Health Effects A Report to the US Centers for Disease Prevention and Control

    E-Print Network [OSTI]

    HEI/CDC/EPA Workshop on Tracking Air Pollution Health Effects 1 #12;2 A Report to the US Centers Tracking of Air Pollution Effects January 15-16, 2008 #12;HEI/CDC/EPA Workshop on Tracking Air Pollution ........................................................................................................................................... 13 AN INCREMENTAL APPROACH TO PUBLIC HEALTH TRACKING OF AIR POLLUTION

  16. United States-Russian workshop on the stochastic health effects of radiation

    SciTech Connect (OSTI)

    NONE

    1992-12-31T23:59:59.000Z

    In August 1988, two years after the Chernobyle accident, the United States and the Soviet Union signed an agreement to sponsor a Joint coordinating Committee on Civilian Nuclear Reactor Safety, (JCCCNRS). The Soviet Union agreed to provide some information on late effects of radiation exposures and to attempt to add some new insights into low dose and low dose rate radiation consequences. At that time, it had just been revealed that significant radiation exposures had occurred in the South Ural Mountains, associated with the early years of operation of the MAYAK nuclear complex. The need to be able to better predict the long term consequences of overexposures, such as occurred with the Chernobyl accident, was a major factor in organizing this workshop. We decided to invite a small number of experts from the Soviet Union, who had direct knowledge of the situation. A small group of American experts was invited to help in a discussion of the state of knowledge of continual low level exposure. The experts and expertise included: Aspects of bask theoretical radiobiological models, studies on experimental animals exposed to chronic or fractionated external or internal radiation, studies on populations exposed to chronic intake and continual exposures, workers exposed to low or high continual levels of radiation. The intent was to begin a dialog on the issue of a better understanding of the dose rate effect in humans. No detailed conclusions could be reached at this first interaction between out two countries, but a model was prepared which seems to support a range of what are known as low dose and dose rate effectiveness factors. A beginning of an evaluation of the role of radiation dose rate on leukemia risk was also accomplished.

  17. Effects of ozone on the respiratory health, allergic sensitization, and cellular immune system in children

    SciTech Connect (OSTI)

    Zwick, H.; Popp, W.; Wagner, C.; Reiser, K.; Schmoeger, J.B.; Boeck, A.H.; Herkner, K.; Radunsky, K. (Pulmonary Department, Krankenhaus Lainz, Vienna (Austria))

    1991-11-01T23:59:59.000Z

    To investigate the lasting effects of high ozone concentrations under environmental conditions, we examined the respiratory health, pulmonary function, bronchial hyperresponsiveness to methacholine, allergic sensitization, and lymphocyte subpopulations of 10- to 14-yr-old children. A total of 218 children recruited from an area with high ozone concentrations (Group A) were tested against 281 children coming from an area with low ozone concentrations (Group B). As to subjective complaints, categorized as 'usually cough with or without phlegm,' 'breathlessness,' and 'susceptibility to chest colds,' there was no difference between the two groups. The lung function parameters were similar, but in Group A subjects' bronchial hyperresponsiveness occurred more frequently and was found to be more severe than in Group B (29.4 versus 19.9%, p less than 0.02; PD20 2,100 {plus minus} 87 versus 2,350 {plus minus} 58 micrograms, p less than 0.05). In both groups the number of children who had been suffering from allergic diseases and sensitization to aeroallergens, found by means of the skin test, was the same. Comparison of the total IgE levels showed no difference at all between the two groups. As far as the white blood cells are concerned, the total and differential cell count was the same, whereas lymphocyte subpopulations showed readily recognizable changes.

  18. Respiratory health effects of the indoor environment in a population of Dutch children

    SciTech Connect (OSTI)

    Dijkstra, L.; Houthuijs, D.; Brunekreef, B.; Akkerman, I.; Boleij, J.S. (Univ. of Wageningen (Netherlands))

    1990-11-01T23:59:59.000Z

    The effect of indoor exposure to nitrogen dioxide on respiratory health was studied over a period of 2 yr in a population of nonsmoking Dutch children 6 to 12 yr of age. Lung function was measured at the schools, and information on respiratory symptoms was collected from a self-administered questionnaire completed by the parents of the children. Nitrogen dioxide was measured in the homes of all children with Palmes' diffusion tubes. In addition, information on smoking and dampness in the home was collected by questionnaire. There was no relationship between exposure to nitrogen dioxide in the home and respiratory symptoms. Respiratory symptoms were found to be associated with exposure to tobacco smoke and home dampness. There was a weak, negative association between maximal midexpiratory flow (MMEF) and exposure to nitrogen dioxide. FEV1, peak expiratory flow, and MMEF were all negatively associated with exposure to tobacco smoke. Home dampness was not associated with pulmonary function. Lung function growth, measured over a period of 2 yr, was not consistently associated with any of the indoor exposure variables. The development of respiratory symptoms over time was not associated with indoor exposure to nitrogen dioxide. There was a significant association between exposure to environmental tobacco smoke in the home and the development of wheeze. There was also a significant association between home dampness and the development of cough.

  19. Chernobyl Studies Project - working group 7.0 environmental transport and health effects. Progress report, October 1993--January 1994

    SciTech Connect (OSTI)

    Hendrickson, S.M. [ed.

    1994-03-01T23:59:59.000Z

    The DOE-funded Chernobyl Studies Project was begun as part of a cooperative agreement between the US and the former USSR, (quote) To develop jointly methods to project rapidly the health effects of any future reactor accident (quote). Most of the initial tasks for this project are completed or near completion. The focus has now turned primarily to the issue of health effects from the Chernobyl accident. Currently, we are extensively engaged in case-control and cohort studies of thyroid diseases among Belarussian children and in the Ukraine. A major part of the effort is providing methods and applications of dose reconstruction and providing support and equipment for the medical teams. This document contains reports on progress in the following task areas: Management; External Dose; Hydrological Transport; Chromosome Painting Dosimetry; Stochastic Effects; Thyroid Studies; and Leukemia Studies.

  20. Human Factors Process Failure Mode and Effects Analysis (HF PFMEA) Application in the Evaluation of Management Risks

    E-Print Network [OSTI]

    Soguilon, Nenita M.

    2009-12-18T23:59:59.000Z

    .3.1. Mechanisms of Prevention ............................................................................................... 11 2.4. Human Factors Process Failure Mode and Effects Analysis (HF PFMEA) ....................... 11 2.5. FMEA Components... ........................................................................................... 15 2.5.5. Risk Priority Number ....................................................................................................... 17 2.6. FMEA Model...

  1. UNIVERSITY OF MIAMI HEALTH SYSTEM NOTICE OF PRIVACY PRACTICES EFFECTIVE DATE: SEPTEMBER 20, 2013

    E-Print Network [OSTI]

    Shyu, Mei-Ling

    health care professionals who provide you with treatment and health care services at such locations that portions of this notice may not apply. If you receive alcohol or substance abuse services or treatment from our substance abuse treatment program, you will receive a separate notice describing how we may use

  2. Sleep-deprivation effect on human performance: a meta-analysis approach

    SciTech Connect (OSTI)

    Candice D. Griffith; Candice D. Griffith; Sankaran Mahadevan

    2006-05-01T23:59:59.000Z

    Human fatigue is hard to define since there is no direct measure of fatigue, much like stress. Instead fatigue must be inferred from measures that are affected by fatigue. One such measurable output affected by fatigue is reaction time. In this study the relationship of reaction time to sleep deprivation is studied. These variables were selected because reaction time and hours of sleep deprivation are straightforward characteristics of fatigue to begin the investigation of fatigue effects on performance. Meta-analysis, a widely used procedure in medical and psychological studies, is applied to the variety of fatigue literature collected from various fields in this study. Meta-analysis establishes a procedure for coding and analyzing information from various studies to compute an effect size. In this research the effect size reported is the difference between standardized means, and is found to be -0.6341, implying a strong relationship between sleep deprivation and performance degradation.

  3. Nuclear winter. The human and environmental consequences of nuclear war

    SciTech Connect (OSTI)

    Harwell, M.A.

    1984-01-01T23:59:59.000Z

    Nuclear Winter is an analysis of the consequences of nuclear war for humans and the environment. It is an account of the world after nuclear war that includes both effects on humans and the phenomenon of nuclear winter. Contents: Foreward by Russell W. Peterson. Introduction. Scenario Development. Initial Conditions: Human Health Effects; State of Physical and Biological Systems; State of Atmospheric Systems; Local Fallout Patterns; Summary of Immediate Effects. Intermediate and Long-Term Consequences: Major Problem Areas: Effects of Reduced Temperatures; Effects of Reduced Light Levels; Effects on Agricultural Production; Societal Disruptions. Relatively Lesser Problem Areas. Recovery Processes. Summary of Consequences.

  4. Effects of Low-Dose Alpha-Particle Irradiation in Human Cells: The Role of Induced Genes and the Bystander Effect. Final Technical Report (9/15/1998-5/31/2005)

    SciTech Connect (OSTI)

    Little, John B.

    2013-09-17T23:59:59.000Z

    This grant was designed to examine the cellular and molecular mechanisms for the bystander effect of radiation (initially described in this laboratory) whereby damage signals are passed from irradiated to non-irradiated cells in a population. These signals induce genetic effects including DNA damage, mutations and chromosomal aberrations in the nonirradiated cells. Experiments were carried out in cultured mammalian cells, primarily human diploid cells, irradiated with alpha particles. This research resulted in 17 publications in the refereed literature and is described in the Progress Report where it is keyed to the publication list. This project was initiated at the Harvard School of Public Health (HSPH) and continued in collaboration with students/fellows at Colorado State University (CSU) and the New Jersey Medical School (NJMS).

  5. Virtual impact: visualizing the potential effects of cosmic impact in human history

    SciTech Connect (OSTI)

    Masse, W Bruce [Los Alamos National Laboratory; Janecky, David R [Los Alamos National Laboratory; Forte, Maurizio [UC MERCED; Barrientos, Gustavo [UNIV OF LA PLATA, ARG.

    2009-01-01T23:59:59.000Z

    Current models indicate that catastrophic impacts by asteroids and comets capable of killing more than one quarter of Earth's human population have occurred on average once every million years; smaller impacts, such the 1908 Tunguska impact that leveled more than 2,000 square km of Siberian forest, occur every 200-300 years. Therefore, cosmic impact likely significantly affected hominine evolution and conceivably played a role in Holocene period human culture history. Regrettably, few archaeologists are trained to appreciate the nature and potential effects of cosmic impact. We have developed a conceptual model for an extensible set of educational and research tools based on virtual reality collaborative environments to engage archaeologists and the general public on the topic of the role of cosmic impact in human history. Our initial focus is on two documented asteroid impacts in Argentina during the period of 4000 to 1000 B.C. Campo del Cicio resulted in an energy release of around 2-3 megatons (100-150 times the Hiroshima atomic weapon), and left several craters and a strewn field covering 493 km{sup 2} in northeastern Argentina. Rio Cuarto was likely more than 1000 megatons and may have devastated an area greater than 50,000 km{sup 2} in central Argentina. We are focusing on reconstructions of these events and their potential effects on contemporary hunter and gatherers. Our vinual reality tools also introduce interactive variables (e.g., impactor physical properties, climate, vegetation, topography, and social complexity) to allow researchers and students to better investigate and evaluate the factors that significantly influence cosmic impact effects.

  6. A framework for human microbiome research

    E-Print Network [OSTI]

    Friedman, Jonathan

    A variety of microbial communities and their genes (the microbiome) exist throughout the human body, with fundamental roles in human health and disease. The National Institutes of Health (NIH)-funded Human Microbiome Project ...

  7. Broadcast news and abortion : the effects of conservative narratives on the reproductive health debate

    E-Print Network [OSTI]

    Jenssen, Mark (Mark Peter)

    2013-01-01T23:59:59.000Z

    How have changes in the elite discussion of reproductive health narratives affected the debate on abortion and influenced state legislation and popular opinion? Using analysis of broadcast transcripts from CNN and FOX News, ...

  8. Chernobyl Studies Project: Working group 7.0, Environmental transport and health effects. Progress report, March--September 1994

    SciTech Connect (OSTI)

    Anspaugh, L.R.; Hendrickson, S.M. [eds.

    1994-12-01T23:59:59.000Z

    In April 1988, the US and the former-USSR signed a Memorandum of Cooperation (MOC) for Civilian Nuclear Reactor Safety; this MOC was a direct result of the accident at the Chernobyl Nuclear Power Plant Unit 4 and the following efforts by the two countries to implement a joint program to improve the safety of nuclear power plants and to understand the implications of environmental releases. A Joint Coordinating Committee for Civilian Nuclear Reactor Safety (JCCCNRS) was formed to implement the MOC. The JCCCNRS established many working groups; most of these were the responsibility of the Nuclear Regulatory Commission, as far as the US participation was concerned. The lone exception was Working Group 7 on Environmental Transport and Health Effects, for which the US participation was the responsibility of the US Department of Energy (DOE). The purpose of Working Group 7 was succintly stated to be, ``To develop jointly methods to project rapidly the health effects of any future nuclear reactor accident.`` To implement the work DOE then formed two subworking groups: 7.1 to address Environmental Transport and 7.2 to address Health Effects. Thus, the DOE-funded Chernobyl Studies Project began. The majority of the initial tasks for this project are completed or near completion. The focus is now turned to the issue of health effects from the Chernobyl accident. Currently, we are involved in and making progress on the case-control and co-hort studies of thyroid diseases among Belarussian children. Dosimetric aspects are a fundamental part of these studies. We are currently working to implement similar studies in Ukraine. A major part of the effort of these projects is supporting these studies, both by providing methods and applications of dose reconstruction and by providing support and equipment for the medical teams.

  9. assessing human risks: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    to Human Health Risk Assessment CPH 418518 Biology and Medicine Websites Summary: SYLLABUS Introduction to Human Health Risk Assessment CPH 418518 SWES 418518 Time: Tuesday...

  10. All mercury lamps contain small amounts of mercury. An electric current passes through the lamp and vaporizes the mercury to generate light. Recycling mercury containing lamps protects human health and our environment from heavy

    E-Print Network [OSTI]

    George, Steven C.

    and vaporizes the mercury to generate light. Recycling mercury containing lamps protects human health and our the environment by recycling universal wastes, contact EH&S at (949) 824-6200 or visit: www.ehs.uci.edu Mercury lamp recycling separates a number of materials for further use in new products. · The mercury is reused

  11. DEPARTMENTOFHEALTHANDHUMANSERVICES National Institutes of Health

    E-Print Network [OSTI]

    Baker, Chris I.

    DEPARTMENTOFHEALTHANDHUMANSERVICES National Institutes of Health Office of Extramural Research 9000 Institutes of Health (NIH), part of the Department of Health and Human Services (DHHS), is the principal health research agency of the U.S. Federal Government. The Office of Extramural Research (OER) provides

  12. Health Behavior Health Promotion -Prevention

    E-Print Network [OSTI]

    Meagher, Mary

    chronic disease complications Improve quality of life Reduce health care costs #12;ImpactHealth Behavior Health Promotion - Prevention Modification of Health Attitudes and Health Behavior #12;Health Promotion: An Overview Basic philosophy Good health = individual and collective goal

  13. On The Chemical Mixture Methodologies for Estimation of the Integrated Health Effects

    E-Print Network [OSTI]

    Taha, Mohamed Ahmed

    2014-11-11T23:59:59.000Z

    and Health Association PAC Protective Action Criteria PEL Permissible Exposure Limit PI Pollution Index viii PODI Point Of Departure Index REACH Registration, Evaluation, Authorization and Restriction of Chemicals RPF Relative Potency Factor... ............................................... 134 APPENDIX G: EXPOSURE LIMITS FOR THE 28 CHEMICALS ............................ 145 APPENDIX H: THE USED HCNS TABLE ................................................................. 150 APPENDIX I: CONCENTRATIONS CONTOURS FOR SELECTED POLLUTANTS...

  14. University of Virginia Health Plan Effective Date: 1/1/2013

    E-Print Network [OSTI]

    Acton, Scott

    HEALTH AND SUBSTANCE ABUSE SERVICES A. Inpatient Acute Care for Non-Biologically Based Mental Illnesses providers Care provided by non-participating providers 1. PLAN COINSURANCE Applies to all expenses unless. PROFESSIONAL SERVICES IN OFFICE OR OUTPATIENT A. Primary Care Physician Visit $10 Copayment $20 Copayment

  15. Community Health Map: A geospatial and multivariate data visualization tool for public health datasets

    E-Print Network [OSTI]

    Shneiderman, Ben

    on health care. The U.S. Department of Health and Human Services keeps track of a variety of health care that enables users to visualize health care data in multivariate space as well as geospatially. It is designed a compre- hensible and powerful interface for policy makers to visualize health care quality, public health

  16. Health Insurance Marketplace Notice New Health Insurance Marketplace...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Options and Your Health Coverage PART A: General Information When key parts of the health care law take effect in 2014, there will be a new way to buy health insurance: the...

  17. Applied Health Sciences May 6, 2010 Class of 2010

    E-Print Network [OSTI]

    Illinois at Chicago, University of

    Applied Health Sciences May 6, 2010 Class of 2010 PRESIDING . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Charlotte A. Tate PRESENTATION OF DEGREE CANDIDATES (see list on page 12) Biomedical and Health Information in · Biomedical Visualization · Health Informatics · Health Information Management Disability and Human

  18. Effect of incentives for medication adherence on health care use and costs in methadone patients with HIV.

    E-Print Network [OSTI]

    Barnett, Paul G; Sorensen, James L; Wong, Wynnie; Haug, Nancy A; Hall, Sharon M

    2009-01-01T23:59:59.000Z

    cial, as substance abuse treatment, medical care, and AIDSsubstance abuse treatment Outpatient mental health careon all health care and substance abuse treatment costs. The

  19. Uptake and cytotoxic effects of multi-walled carbon nanotubes in human bronchial epithelial cells

    SciTech Connect (OSTI)

    Hirano, Seishiro, E-mail: seishiro@nies.go.j [Environmental Nanotoxicology Section, RCER, National Institute for Environmental Studies (Japan); Fujitani, Yuji; Furuyama, Akiko [Environmental Nanotoxicology Section, RCER, National Institute for Environmental Studies (Japan); Kanno, Sanae [Photon Medical Research Center, Hamamatsu University School of Medicine (Japan)

    2010-11-15T23:59:59.000Z

    Carbon nanotubes (CNT) are cytotoxic to several cell types. However, the mechanism of CNT toxicity has not been fully studied, and dosimetric analyses of CNT in the cell culture system are lacking. Here, we describe a novel, high throughput method to measure cellular uptake of CNT using turbimetry. BEAS-2B, a human bronchial epithelial cell line, was used to investigate cellular uptake, cytotoxicity, and inflammatory effects of multi-walled CNT (MWCNT). The cytotoxicity of MWCNT was higher than that of crocidolite asbestos in BEAS-2B cells. The IC{sub 50} of MWCNT was 12 {mu}g/ml, whereas that of asbestos (crocidolite) was 678 {mu}g/ml. Over the course of 5 to 8 h, BEAS-2B cells took up 17-18% of the MWCNT when they were added to the culture medium at a concentration of 10 {mu}g/ml. BEAS-2B cells were exposed to 2, 5, or 10 {mu}g/ml of MWCNT, and total RNA was extracted for cytokine cDNA primer array assays. The culture supernatant was collected for cytokine antibody array assays. Cytokines IL-6 and IL-8 increased in a dose dependent manner at both the mRNA and protein levels. Migration inhibitory factor (MIF) also increased in the culture supernatant in response to MWCNT. A phosphokinase array study using lysates from BEAS-2B cells exposed to MWCNT indicated that phosphorylation of p38, ERK1, and HSP27 increased significantly in response to MWCNT. Results from a reporter gene assays using the NF-{kappa}B or AP-1 promoter linked to the luciferase gene in transiently transfected CHO-KI cells revealed that NF-{kappa}B was activated following MWCNT exposure, while AP-1 was not changed. Collectively, MWCNT activated NF-{kappa}B, enhanced phosphorylation of MAP kinase pathway components, and increased production of proinflammatory cytokines in human bronchial epithelial cells.

  20. An evaluation of theories concerning the health effects of low-dose radiation exposures

    E-Print Network [OSTI]

    Wei, Elizabeth J. (Elizabeth Jay)

    2012-01-01T23:59:59.000Z

    The danger of high, acute doses of radiation is well documented, but the effects of low-dose radiation below 100 mSv is still heavily debated. Four theories concerning the effects of lowdose radiation are presented here: ...

  1. Health-Compromising Behaviors characteristics

    E-Print Network [OSTI]

    Meagher, Mary

    , cognitive impairments, 15% of health care costs = Etoh abuse treatment, underestimate of health costsHealth-Compromising Behaviors characteristics substance abuse and dependence ­ opponent process theory ­ incentive salience ­ frontal executive effects alcohol abuse and dependence smoking #12

  2. Health risk assessment of environmental exposure to trichloroethylene

    SciTech Connect (OSTI)

    Brown, L.P.; Farrar, D.G.; de Rooij, C.G. (Epidemiology Unit, Alderley Park, Macclesfield, Cheshire (England))

    1990-02-01T23:59:59.000Z

    A review of the animal data showed trichloroethylene (TRI) to be of low acute toxicity. Repeated exposure showed that the target organs were the liver, and to a lesser extent, the kidney. TRI is not mutagenic or only marginally mutagenic. There is no evidence of fetotoxicity or teratogenicity. TRI is judged not to exhibit chronic neurotoxicity. Lifetime bioassays resulted in tumors in both the mouse and the rat. However, because of qualitative and quantitative metabolic differences between rodent and human, no one suitable tumor site can be chosen for human health risk assessment. In addition, of the several epidemiology studies, none has demonstrated a positive association for increased tumor incidence. A review of the health effects in humans shows TRI to be of low acute toxicity and, following chronic high doses, to be hepatotoxic. Environmental exposure to TRI is mainly via the atmosphere, while the contribution from exposure to drinking water and foodstuffs is negligible. The total body burden was calculated as 22 micrograms/day. The safety margin approach based on human health effects showed that TRI levels are well within the safety margin for the human no-observable-effect level (10,000 times lower). The total body burden represents a risk of 1.4 X 10(-5) by linearized multistage modeling. Therefore, by either methodological approach to risk assessment, the environmental occurrence of TRI does not represent a significant health risk to the general population or to the population in areas close to industrial activities. 66 references.

  3. Re-Visiting Health Informatics What is Health Informatics?

    E-Print Network [OSTI]

    Abidi, Syed Sibte Raza

    and the quality of care Facilitate remote healthcare at a patient's home #12;What do Health Informaticians DoRe-Visiting Health Informatics HINF1100 Fall 2008 #12;What is Health Informatics? · Health the effective organization, analysis, management and use of health information to improve the delivery

  4. The effects of level of automation and adaptive automation on human performance, situation awareness and workload in a

    E-Print Network [OSTI]

    Kaber, David B.

    The effects of level of automation and adaptive automation on human performance, situation., 4731 East Forest Peak, Marietta, GA 30066, USA Keywords: Level of automation (LOA); adaptive automation of automation (LOAs) for maintaining operator involvement in complex systems control and facilitating situation

  5. Community Health & Public Health

    E-Print Network [OSTI]

    Jiang, Huiqiang

    Community Health & Public Health Preparedness in the Marcellus Shale Era 2011 Pennsylvania Public Photo credit: Pittsburgh Tribune- Review, Keith Hodan #12;Safety by the Numbers PA Marcellus Citations. Conference presentation, Spain. · County Commissioners Association of Pennsylvania (CCAP). (2010). Marcellus

  6. Health-related effects reproted by electronic cigarette users in online forums

    E-Print Network [OSTI]

    Talbot, Prue

    2013-01-01T23:59:59.000Z

    effects were sometimes opposites, eg, improved cough andworsened cough were reported by different individuals. Somereports, such as “developed cough” or “cough worsened”,

  7. Effect of Salt Stress on Purslane and Potential Health Benefits: Oxalic Acid and Fatty Acids Profile

    E-Print Network [OSTI]

    Carvalho, Isabel S.; Teixeira, Mónica; Brodelius, Maria

    2009-01-01T23:59:59.000Z

    IS. 2009. Effects of salt stress on purslane (Portulacaacid concentration occurs when the salt stress concentrationfor higher concentration of salt in both purslanes. In GL

  8. Human Health and Ecological Risk Assessment for the Operation of the Explosives Waste Treatment Facility at Site 300 of the Lawrence Livermore National Laboratory

    SciTech Connect (OSTI)

    Gallegos, G; Daniels, J; Wegrecki, A

    2007-10-01T23:59:59.000Z

    This document contains the human health and ecological risk assessment for the Resource Recovery and Conservation Act (RCRA) permit renewal for the Explosives Waste Treatment Facility (EWTF). Volume 1 is the text of the risk assessment, and Volume 2 (provided on a compact disc) is the supporting modeling data. The EWTF is operated by the Lawrence Livermore National Laboratory (LLNL) at Site 300, which is located in the foothills between the cities of Livermore and Tracy, approximately 17 miles east of Livermore and 8 miles southwest of Tracy. Figure 1 is a map of the San Francisco Bay Area, showing the location of Site 300 and other points of reference. One of the principal activities of Site 300 is to test what are known as 'high explosives' for nuclear weapons. These are the highly energetic materials that provide the force to drive fissionable material to criticality. LLNL scientists develop and test the explosives and the integrated non-nuclear components in support of the United States nuclear stockpile stewardship program as well as in support of conventional weapons and the aircraft, mining, oil exploration, and construction industries. Many Site 300 facilities are used in support of high explosives research. Some facilities are used in the chemical formulation of explosives; others are locations where explosive charges are mechanically pressed; others are locations where the materials are inspected radiographically for such defects as cracks and voids. Finally, some facilities are locations where the machined charges are assembled before they are sent to the onsite test firing facilities, and additional facilities are locations where materials are stored. Wastes generated from high-explosives research are treated by open burning (OB) and open detonation (OD). OB and OD treatments are necessary because they are the safest methods for treating explosives wastes generated at these facilities, and they eliminate the requirement for further handling and transportation that would be required if the wastes were treated off site.

  9. Effects of ambient sulfur oxides and suspended particles on respiratory health of preadolescent children

    SciTech Connect (OSTI)

    Ware, J.H.; Ferris, B.G. Jr.; Dockery, D.W.; Spengler, J.D.; Stram, D.O.; Speizer, F.E.

    1986-05-01T23:59:59.000Z

    Reported here are the results from an ongoing study of outdoor air pollution and respiratory health of children living in six cities in the eastern and midwestern United States. The study enrolled 10,106 white preadolescent children between 1974 and 1977 in 3 successive annual visits to each city. Each child received a spirometric examination, and a parent completed a standard questionnaire. Of this cohort, 8,380 children were seen for a second examination 1 yr later. An air pollution monitoring program was begun in each community at about the time of the first examination. For this report, measurements of total suspended particulates (TSP), the sulfate fraction of TSP (TSO/sub 4/), and sulfur dioxide (SO2) concentrations at study-affiliated outdoor stations were combined with measurements at other public and private monitoring sites to create a record of TSP, TSO/sub 4/, and SO/sub 2/ concentrations in each of 9 air pollution regions during the 1-yr period preceding each examination and, for TSP, during each child's lifetime up to the time of testing. Across the 6 cities, frequency of cough was significantly associated with the average of 24-h mean concentrations of all 3 air pollutants during the year preceding the health examination (p less than 0.01). Rates of bronchitis and a composite measure of lower respiratory illness were significantly associated with average particulate concentrations (p less than 0.05). In analyses restricted to lifetime residents, these outcomes were significantly associated with measures of lifetime mean TSP concentration. Within the cities, however, temporal and spatial variation in air pollutant concentrations and illness and symptom rates were not positively associated.

  10. Respiratory health effects associated with ambient sulfates and ozone in two rural Canadian communities

    SciTech Connect (OSTI)

    Stern, B.; Jones, L.; Raizenne, M.; Burnett, R.; Meranger, J.C.; Franklin, C.A.

    1989-06-01T23:59:59.000Z

    A cross-sectional epidemiological study investigating the respiratory health of children in two Canadian communities was conducted in 1983-1984 in Tillsonburg, Ontario, located in a region of moderately elevated concentrations of transported air pollutants, and in Portage la Prairie, Manitoba, situated in a low pollution area. There were no significant local sources of industrial emissions in either community. Seven hundred and thirty-five children aged 7-12 were studied in the first town and 895 in the second. Respiratory health was assessed by the measurement of the forced vital capacity (FVC) and forced expiratory volume in 1 sec (FEV1.0) of each child, and by evaluation of the child's respiratory symptoms and illnesses using a parent-completed questionnaire. Sulfur dioxide (SO2), sulfate, and particulate nitrate levels were significantly higher in Tillsonburg than in Portage la Prairie (P less than 0.05), but nitrogen dioxide (NO2) and inhalable particles (PM10) differed little between the communities. Historical data in the vicinity of Tillsonburg indicated that average annual levels of sulfates, total nitrates, and ozone (O3) did not vary markedly in the 9-year period preceding the study. The results show that Tillsonburg children had statistically significant (P less than 0.001) lower levels of 2% for FVC and 1.7% for FEV1.0 as compared with children in Portage la Prairie. These differences could not be explained by parental smoking or education, the use of gas cooking or wood heating fuels, pollution levels on the day of testing, or differences in age, sex, height, or weight. With the exception of inhalant allergies, which occurred more frequently in Tillsonburg children, the prevalence of chronic respiratory symptoms and illnesses was similar in the two communities.

  11. Effects of maternal stress and obesity on human feto-placental glucocorticoid exposure 

    E-Print Network [OSTI]

    O'Reilly, James Richard

    2014-07-05T23:59:59.000Z

    Fetal exposure to excess glucocorticoids has been proposed as a key determinant of pregnancy outcome, as well as a predictor of long term health of the offspring through a phenomenon known as ‘developmental programming’. ...

  12. HumanWildlife Interactions 4(1):112117, Spring 2010 An effective chemical deterrent for invasive

    E-Print Network [OSTI]

    on ecosystems and economies, and many cause problems for humans. One such problem is the loss of electrical (Osteopilus septentrionalis) are known to cause power outages and are a nuisance to humans when they invade-related power outages and reduce conflicts with residents in the urbanized areas preferred by these invasive

  13. Thyroid organotypic rat and human cultures used to investigate drug effects on thyroid function, hormone synthesis and release pathways

    SciTech Connect (OSTI)

    Vickers, Alison E.M., E-mail: vickers_alison@allergan.com [Drug Safety Evaluation, Allergan Inc., 2525 Dupont Dr, Irvine CA 92612 (United States); Heale, Jason; Sinclair, John R.; Morris, Stephen; Rowe, Josh M. [Drug Safety Evaluation, Allergan Inc., 2525 Dupont Dr, Irvine CA 92612 (United States)] [Drug Safety Evaluation, Allergan Inc., 2525 Dupont Dr, Irvine CA 92612 (United States); Fisher, Robyn L. [Vitron Inc., Tucson, AZ (United States)] [Vitron Inc., Tucson, AZ (United States)

    2012-04-01T23:59:59.000Z

    Drug induced thyroid effects were evaluated in organotypic models utilizing either a rat thyroid lobe or human thyroid slices to compare rodent and human response. An inhibition of thyroid peroxidase (TPO) function led to a perturbation in the expression of key genes in thyroid hormone synthesis and release pathways. The clinically used thiourea drugs, methimazole (MMI) and 6-n-propyl-2-thioruacil (PTU), were used to evaluate thyroid drug response in these models. Inhibition of TPO occurred early as shown in rat thyroid lobes (2 h) and was sustained in both rat (24–48 h) and human (24 h) with ? 10 ?M MMI. Thyroid from rats treated with single doses of MMI (30–1000 mg/kg) exhibited sustained TPO inhibition at 48 h. The MMI in vivo thyroid concentrations were comparable to the culture concentrations (? 15–84 ?M), thus demonstrating a close correlation between in vivo and ex vivo thyroid effects. A compensatory response to TPO inhibition was demonstrated in the rat thyroid lobe with significant up-regulation of genes involved in the pathway of thyroid hormone synthesis (Tpo, Dio1, Slc5a5, Tg, Tshr) and the megalin release pathway (Lrp2) by 24 h with MMI (? 10 ?M) and PTU (100 ?M). Similarly, thyroid from the rat in vivo study exhibited an up-regulation of Dio1, Slc5a5, Lrp2, and Tshr. In human thyroid slices, there were few gene expression changes (Slc5a5, ? 2-fold) and only at higher MMI concentrations (? 1500 ?M, 24 h). Extended exposure (48 h) resulted in up-regulation of Tpo, Dio1 and Lrp2, along with Slc5a5 and Tshr. In summary, TPO was inhibited by similar MMI concentrations in rat and human tissue, however an increased sensitivity to drug treatment in rat is indicated by the up-regulation of thyroid hormone synthesis and release gene pathways at concentrations found not to affect human tissue. -- Highlights: ? Novel model of rat thyroid or human thyroid slices to evaluate pathways of injury. ? TPO inhibition by MMI or PTU altered hormone synthesis and release genes. ? Rat thyroid was more sensitive to the drug effects than human tissue.

  14. Engineering VA Health Care

    E-Print Network [OSTI]

    Adams, Mark

    Engineering VA Health Care The Department of Veterans Affairs is offering a unique career to all regions of the country and toward numerous health care leadership roles. B.S. degree or M engineers to be effective Healthcare Technology Program Managers in the Veterans Health Administration

  15. Space Science Technology Health General Sci-fi & Gaming Oddities International Business Politics Education Entertainment Sports Better Than The Human Eye

    E-Print Network [OSTI]

    Rogers, John A.

    Education Entertainment Sports Better Than The Human Eye Posted on: Monday, 17 January 2011, 22:22 CST Tiny a curvilinear camera, much like the human eye, with the significant feature of a zoom capability, unlike the human eye. The "eyeball camera" has a 3.5x optical zoom, takes sharp images, is inexpensive to make

  16. Home National World Business Sports Cricket Entertainment Health Science Bollywood Celebs Geekwerks New curvilinear camera adds a zoom to the `human eye'

    E-Print Network [OSTI]

    Rogers, John A.

    Geekwerks New curvilinear camera adds a zoom to the `human eye' From ANI Washington, Jan 18: Researchers have developed a curvilinear camera that mimics the human eye, but has the added feature of zooming-vision surveillance, robotic vision, endoscopic imaging and consumer electronics. "We were inspired by the human eye

  17. Cytotoxicity and inhibitory effects of low-concentration triclosan on adipogenic differentiation of human mesenchymal stem cells

    SciTech Connect (OSTI)

    Guo, Li-Wu [Division of Personalized Nutrition and Medicine, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079 (United States)] [Division of Personalized Nutrition and Medicine, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079 (United States); Wu, Qiangen [Division of Biochemical Toxicology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079 (United States)] [Division of Biochemical Toxicology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079 (United States); Green, Bridgett; Nolen, Greg [Division of Personalized Nutrition and Medicine, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079 (United States)] [Division of Personalized Nutrition and Medicine, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079 (United States); Shi, Leming [Division of Systems Biology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079 (United States)] [Division of Systems Biology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079 (United States); LoSurdo, Jessica [Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892 (United States)] [Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892 (United States); Deng, Helen [Arkansas Department of Health, Little Rock, AR 72205 (United States)] [Arkansas Department of Health, Little Rock, AR 72205 (United States); Bauer, Steven [Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892 (United States)] [Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892 (United States); Fang, Jia-Long, E-mail: jia-long.fang@fda.hhs.gov [Division of Biochemical Toxicology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079 (United States)] [Division of Biochemical Toxicology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079 (United States); Ning, Baitang, E-mail: baitang.ning@fda.hhs.gov [Division of Personalized Nutrition and Medicine, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079 (United States)] [Division of Personalized Nutrition and Medicine, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079 (United States)

    2012-07-15T23:59:59.000Z

    Humans at all ages are continually exposed to triclosan (TCS), a widely used antimicrobial agent that can be found in many daily hygiene products, such as toothpastes and shampoos; however, the toxicological and biological effects of TCS in the human body after long-term and low-concentration exposure are far from being well understood. In the current study, we investigated the effects of TCS on the differentiation of human mesenchymal stem cells (hMSCs) by measuring the cytotoxicity, morphological changes, lipid accumulation, and the expression of adipocyte differentiation biomarkers during 21-day adipogenesis. Significant cytotoxicity was observed in un-induced hMSCs treated with high-concentration TCS (? 5.0 ?M TCS), but not with low-concentration treatments (? 2.5 ?M TCS). TCS inhibited adipocyte differentiation of hMSCs in a concentration-dependent manner in the 0.156 to 2.5 ?M range as indicated by morphological changes with Oil Red O staining, which is an index of lipid accumulation. The inhibitory effect was confirmed by a decrease in gene expression of specific adipocyte differentiation biomarkers including adipocyte protein 2, lipoprotein lipase, and adiponectin. Our study demonstrates that TCS inhibits adipocyte differentiation of hMSCs under concentrations that are not cytotoxic and in the range observed in human blood. -- Highlights: ? TCS is cytotoxic to un-induced hMSCs at concentrations ? 5.0 ?M. ? TCS at concentrations ? 2.5 ?M is not cytotoxic to induced hMSCs. ? TCS at non-cytotoxic concentrations inhibits lipid formation in induced hMSCs. ? TCS decreases the expression of specific biomarkers of adipocyte differentiation. ? TCS at concentrations observed in human blood inhibits adipogenesis of hMSCs.

  18. Health technology : design of bandage-sized wireless sensors and effect of ambient displays on social support and diabetes management

    E-Print Network [OSTI]

    Mohan, Akshay, 1979-

    2004-01-01T23:59:59.000Z

    Health-Zero refers to health technology design that focus on interaction with an individual as a whole to promote well-being. This thesis presents two explorations in the discipline. The first exploration involves the ...

  19. INSTITUTE FOR PUBLIC HEALTH AND MEDICINE AT

    E-Print Network [OSTI]

    Engman, David M.

    INSTITUTE FOR PUBLIC HEALTH AND MEDICINE AT NORTHWESTERN MEDICINE CENTER FOR PATIENT- CENTERED FOR PUBLIC HEALTH AND MEDICINE AT NORTHWESTERN MEDICINE CENTER FOR PATIENT-CENTERED OUTCOMES "Our work often seeks to understand human behavior and its interface with pressing health issues. We focus on the human

  20. The Effect of Degraded Digital Instrumentation and Control systems on Human-system Interfaces and Operator Performance

    SciTech Connect (OSTI)

    OHara, J.M.; Gunther, B.; Martinez-Guridi, G. (BNL); Xing, J.; Barnes, V. (NRC)

    2010-11-07T23:59:59.000Z

    Integrated digital instrumentation and control (I&C) systems in new and advanced nuclear power plants (NPPs) will support operators in monitoring and controlling the plants. Even though digital systems typically are expected to be reliable, their potential for degradation or failure significantly could affect the operators performance and, consequently, jeopardize plant safety. This U.S. Nuclear Regulatory Commission (NRC) research investigated the effects of degraded I&C systems on human performance and on plant operations. The objective was to develop technical basis and guidance for human factors engineering (HFE) reviews addressing the operator's ability to detect and manage degraded digital I&C conditions. We reviewed pertinent standards and guidelines, empirical studies, and plant operating experience. In addition, we evaluated the potential effects of selected failure modes of the digital feedwater control system of a currently operating pressurized water reactor (PWR) on human-system interfaces (HSIs) and the operators performance. Our findings indicated that I&C degradations are prevalent in plants employing digital systems, and the overall effects on the plant's behavior can be significant, such as causing a reactor trip or equipment to operate unexpectedly. I&C degradations may affect the HSIs used by operators to monitor and control the plant. For example, deterioration of the sensors can complicate the operators interpretation of displays, and sometimes may mislead them by making it appear that a process disturbance has occurred. We used the findings as the technical basis upon which to develop HFE review guidance.

  1. Characterization of information requirements for studies of CO/sub 2/ effects: water resources, agriculture, fisheries, forests and human health

    SciTech Connect (OSTI)

    White, M R [ed.

    1985-12-01T23:59:59.000Z

    The report discusses how climate change and vegetative response will affect selected areas of our way of life as a result of increased carbon dioxide concentrations. Needs for future research are identified. Separate abstracts have been prepared for individual chapters. (ACR)

  2. Tree and forest effects on air quality and human health in the United David J. Nowak a, *

    E-Print Network [OSTI]

    ). These pollutants are: carbon monoxide (CO), nitrogen dioxide (NO2), ozone (O3), lead (Pb), sulfur dioxide (SO2 by intercepting particles, emitting particles (e.g., pollen) and resuspension of particles captured on the plant

  3. Johns Hopkins individualized Health Initiative Hopkins inHealth

    E-Print Network [OSTI]

    Niebur, Ernst

    ;$2,593,644,000,000 #12;#12;#12;Why is U.S. health care so much more "expensive" but not more effective than in most OECD disease? #12;Older? #12;McKinsey Global Institute. 2008. Accounting for the costs of US health care: A newJohns Hopkins individualized Health Initiative Hopkins inHealth Scott L. Zeger Professor

  4. Energy Systems and Population Health

    SciTech Connect (OSTI)

    Ezzati, Majid; Bailis, Rob; Kammen, Daniel M.; Holloway, Tracey; Price, Lynn; Cifuentes, Luis A.; Barnes, Brendon; Chaurey, Akanksha; Dhanapala, Kiran N.

    2004-04-12T23:59:59.000Z

    It is well-documented that energy and energy systems have a central role in social and economic development and human welfare at all scales, from household and community to regional and national (41). Among its various welfare effects, energy is closely linked with people s health. Some of the effects of energy on health and welfare are direct. With abundant energy, more food or more frequent meals can be prepared; food can be refrigerated, increasing the types of food items that are consumed and reducing food contamination; water pumps can provide more water and eliminate the need for water storage leading to contamination or increased exposure to disease vectors such as mosquitoes or snails; water can be disinfected by boiling or using other technologies such as radiation. Other effects of energy on public health are mediated through more proximal determinants of health and disease. Abundant energy can lead to increased irrigation, agricultural productivity, and access to food and nutrition; access to energy can also increase small-scale income generation such as processing of agricultural commodities (e.g., producing refined oil from oil seeds, roasting coffee, drying and preserving fruits and meats) and production of crafts; ability to control lighting and heating allows education or economic activities to be shielded from daily or seasonal environmental constraints such as light, temperature, rainfall, or wind; time and other economic resources spent on collecting and/or transporting fuels can be used for other household needs if access to energy is facilitated; energy availability for transportation increases access to health and education facilities and allow increased economic activity by facilitating the transportation of goods and services to and from markets; energy for telecommunication technology (radio, television, telephone, or internet) provides increased access to information useful for health, education, or economic purposes; provision of energy to rural and urban health facilities allows increased delivery and coverage of 3 various health services and interventions such as tests and treatments, better storage of medicine and vaccines, disinfection of medical equipment by boiling or radiation, and more frequent and efficient health system encounters through mobile clinics or longer working hours; and so on. In fact, while the dominant view of development-energy-health linkages has been that improvements in energy and health are outcomes of the socioeconomic development process (e.g., the ''energy ladder'' framework discussed below), it has even been argued that access to higher quality energy sources and technologies can initiate a chain of demographic, health, and development outcomes by changing the household structure and socioeconomic relationships. For example, in addition to increased opportunities for food and income production, reduced infant mortality as a result of transition to cleaner fuels or increased coverage of vaccination with availability of refrigerators in rural clinics may initiate a process of ''demographic transition'' to low-mortality and low-fertility populations (14). Such a transition has historically been followed with further improvements in maternal and child health and increased female participation in the labor markets and other economic activities.

  5. The Health Risks: Seafood Contamination, Harmful Algal

    E-Print Network [OSTI]

    health products from the sea. What is the central issue? Why should I care? How will OHH researchThe Health Risks: Seafood Contamination, Harmful Algal Blooms and Polluted Beaches Seafood associated public health costs. Announcing a New Interagency Report on Oceans and Human Health Research

  6. ZHU, BIWEN. Assessing the Effects of Feedback Type and Modality on Motor Skill Learning and Human Motivation. (Under the direction of Dr. David B. Kaber).

    E-Print Network [OSTI]

    Kaber, David B.

    ABSTRACT ZHU, BIWEN. Assessing the Effects of Feedback Type and Modality on Motor Skill Learning of Feedback Type and Modality on Motor Skill Learning and Human Motivation by Biwen Zhu A dissertation and Human Motivation. (Under the direction of Dr. David B. Kaber). Two types of feedback, including

  7. University Services University Health and Safety

    E-Print Network [OSTI]

    Minnesota, University of

    Management Storm and Waste Water Compliance Promote Environmental Health Drinking Water Quality Human with environmental, health and safety standards, rules and best practices. Through partnerships with units with Capital Planning and Project Management, Facilities Management and academic departments throughout

  8. Assessing health impacts of CO2 leakage from a geological storage site into buildings: role of attenuation in the unsaturated zone and building foundation

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    a) Title Assessing health impacts of CO2 leakage from a geological storage site into buildings of the greenhouse gas CO2 has the potential to be a widespread and effective option to mitigate climate change. As any industrial activity, CO2 storage may lead to adverse impact on human health and the environment

  9. Secondary Organic Aerosol Formation From the Heterogeneous Chemistry of Isoprene-Derived Epoxides: Implications for Air Quality, Climate and Public Health

    E-Print Network [OSTI]

    Lin, Qiao

    through aerosol-cloud interactions, and is associated with adverse effects on human health. Globally Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina at Chapel.5 µm) impacts Earth's climate directly through scattering/absorbing solar radiation and indirectly

  10. The effect of weightlessness on cytoskeleton architecture and proliferation of human breast

    E-Print Network [OSTI]

    Portet, Stéphanie

    was kept in a 1g centrifuge (1g in-flight control). Human breast cancer cells MCF-7, flown in space launching), cells were more fully spread in 1g in-flight control than in g. The fraction of cycling MCF-7. Finally, MCF-7 cell proliferation was reduced in g. 3. Some MCF-7 clusters showed altered microtubules (MT

  11. HumanWildlife Interactions 6(2): Fall 2012 Effects of grassland alteration from mowing

    E-Print Network [OSTI]

    , Dolbeer et al. 2009). According to the U.S. Federal Aviation Administration (FAA), the average annual cost and aircraft (i.e., bird strikes) have occurred since the beginning of aviation and have resulted in human of bird and other wildlife strikes in the United States to the civil aviation industry is estimated

  12. Using Embryonic Stem Cells as a Novel Model to Compare the Toxicological Effects of Harm Reduction and Conventional Cigarette Smoke on Early Embryo Development

    E-Print Network [OSTI]

    Lin, Sabrina Chia-Chin

    2010-01-01T23:59:59.000Z

    Department of Health and Human Services, Centers for DiseaseDepartment of Health and Human Services, Centers for Disease

  13. "Sometimes they used to whisper in our ears": health care workers' perceptions of the effects of abortion legalization in Nepal

    E-Print Network [OSTI]

    2012-01-01T23:59:59.000Z

    Population and Government of Nepal. Kathmandu: Ministry ofand Macro International Inc: Nepal Demographic Health SurveyCREHPA): Unsafe Abortion Nepal Country Profile. Kathmandu:

  14. Innovative . Flexible . RegionalInnovative . Flexible . Regional Health Care

    E-Print Network [OSTI]

    Shihadeh, Alan

    Executive Master in Innovative . Flexible . RegionalInnovative . Flexible . Regional Health Care Learning Outcomes Health Systems, Policy and Reform - Communicating with Policy Makers - Evidence - Human Resources Management - Data and Decision Making Executive Master in Health Care Leadership (EMHCL

  15. USGS National Wildlife Health Center Diagnostic Case Submission Guidelines

    E-Print Network [OSTI]

    USGS National Wildlife Health Center Diagnostic Case Submission Guidelines The following guidelines broadly outline the framework used by the National Wildlife Health Center (NWHC to the submitting agency, its wildlife populations, or domestic animal and human health. Type of Specimens

  16. Change What? Identifying Quality Improvement Targets by Investigating Usual Mental Health Care

    E-Print Network [OSTI]

    Garland, Ann F.; Bickman, Leonard; Chorpita, Bruce F.

    2010-01-01T23:59:59.000Z

    satisfaction with mental health services and changes indon’t we have effective mental health services? [Editorial].Mental Health and Mental Health Services Research, 35, 437–

  17. Study of the exposure of British mineworkers to nitrous fumes and the effects on their health. Final report August 77-January 80

    SciTech Connect (OSTI)

    Robertson, A.; Collings, P.; Gormley, I.P.; Dodgeon, J.

    1981-06-01T23:59:59.000Z

    Shift-average exposures to nitric oxide and nitrogen dioxide have been found to be well within the recommended safety limits in nine British collieries. Differences in the exposures of miners in different collieries and between different locations and occupations within collieries were observed, with diesel locomotive drivers having consistently higher shift-average exposures than other workers. Possible health effects of oxides of nitrogen were investigated by comparing the respiratory health of men with low past exposure against men with higher past exposure to these gases. No differences in forced expired volumes in one second or in the prevalences of cough, phlegm and breathlessness were found between the two population groups.

  18. Audio visual information fusion for human activity analysis

    E-Print Network [OSTI]

    Thagadur Shivappa, Shankar

    2010-01-01T23:59:59.000Z

    recorded in a health smart home,” in LREC 2010 workshop onto the system. Health smart homes and assisted living forintelligent vehicles, smart homes and natural human-computer

  19. Effects of an Advanced Reactor’s Design, Use of Automation, and Mission on Human Operators

    SciTech Connect (OSTI)

    Jeffrey C. Joe; Johanna H. Oxstrand

    2014-06-01T23:59:59.000Z

    The roles, functions, and tasks of the human operator in existing light water nuclear power plants (NPPs) are based on sound nuclear and human factors engineering (HFE) principles, are well defined by the plant’s conduct of operations, and have been validated by years of operating experience. However, advanced NPPs whose engineering designs differ from existing light-water reactors (LWRs) will impose changes on the roles, functions, and tasks of the human operators. The plans to increase the use of automation, reduce staffing levels, and add to the mission of these advanced NPPs will also affect the operator’s roles, functions, and tasks. We assert that these factors, which do not appear to have received a lot of attention by the design engineers of advanced NPPs relative to the attention given to conceptual design of these reactors, can have significant risk implications for the operators and overall plant safety if not mitigated appropriately. This paper presents a high-level analysis of a specific advanced NPP and how its engineered design, its plan to use greater levels of automation, and its expanded mission have risk significant implications on operator performance and overall plant safety.

  20. Analysis of Senate Bill 576: Health Care Coverage for Tobacco Cessation Services

    E-Print Network [OSTI]

    California Health Benefits Review Program (CHBRP)

    2005-01-01T23:59:59.000Z

    dependence: A US public health service report. The tobaccoHuman Services. Public Health Service. Javitz HS, Swan GE,Health. U.S. Public Health Service (PHS). (2000). Treating

  1. health effects Flow cytometry

    E-Print Network [OSTI]

    /K-T boundary research "Mike" shot 253Es, 255Fm elements discovered 1952 2009 - Nuclear forensics: HIV 1994: HPV 1996: Influenza 1998: STD 1999: Chem-Bio High Throughput Laboratory Network National Laboratory Gene Library Project GenBank TB Structural Genomics Consortium Bioforensics Analysis Research

  2. The EU's Human Rights Obligations in Relation to Policies with Extraterritorial Effects

    E-Print Network [OSTI]

    Bartels, Lorand

    2014-04-09T23:59:59.000Z

    in their territory to cause harm to other states. This obligation is usually dated to the 1941 Trail Smelter arbitration, in which it was said that ‘no State has the right to use or permit the use of its territory in such a manner as to cause injury by fumes... and equipment [2008] OJ L335/99 requires EU Member States to ‘exercise special caution and vigilance in issuing licences … to countries where serious violations of human rights have been established …’. 49 Trail Smelter (US/Canada) (1941) 3 RIAA 1905...

  3. Roadmap: School Health Education -Health and Physical Education -Bachelor of Science in Education

    E-Print Network [OSTI]

    Sheridan, Scott

    Roadmap: School Health Education - Health and Physical Education - Bachelor of Science in Education [EH-BSE-SHED-HPE] College of Education, Health and Human Services School of Health Sciences Catalog Year: 2012-2013 Page 1 of 3 | Last Updated: 22-May-12/JS This roadmap is a recommended semester

  4. Roadmap: School Health Education -Health and Physical Education -Bachelor of Science in Education

    E-Print Network [OSTI]

    Sheridan, Scott

    Roadmap: School Health Education - Health and Physical Education - Bachelor of Science in Education [EH-BSE-SHED-HPE] College of Education, Health and Human Services School of Health Sciences Catalog Year: 2013-2014 Page 1 of 3 | Last Updated: 4-June-13/JS This roadmap is a recommended semester

  5. Appendix Tables and Data Appendices, Effects of Increased Access to Infertility Treatment on Infant and Child Health: Evidence from

    E-Print Network [OSTI]

    Silver, Whendee

    and Child Health: Evidence from Health Insurance Mandates Marianne P. Bitler University of California to unmarried women 0.28 0.28 Obstetric beds/1000 women 15­44 1.03 1.03 Neonatal intensive care beds/1000 women 15­44 0.19 0.19 Neonatal intermediate care beds/1000 women 15­44 0.08 0.08 Summary statistics for all

  6. EAT SMART Sources: Heart Health

    E-Print Network [OSTI]

    -1- EAT SMART Sources: Heart Health American Dietetic Association Complete Food and Nutrition Guide and Promotion; Home and Garden Bulletin Number 252; August 1992. Heart Attach Signs, U.S. Department of Health and Human Services: National Institutes of Heart, Lung, and Blood Institute, NIH Publication No. 01

  7. The effect of continuous infusion of human parathyroid hormone on bone architecture in female mice

    E-Print Network [OSTI]

    Eisenberg, Rahel E. (Rahel Esther)

    2009-01-01T23:59:59.000Z

    This research sought to create an animal model of secondary hyperparathyroidism through continuous infusion of parathyroid hormone (PTH) in adult female mice, and to subsequently study the catabolic effects of PTH. Osmotic ...

  8. ENVIRONMENTALENVIRONMENTALENVIRONMENTAL SCIENCE & HEALTHSCIENCE & HEALTHSCIENCE & HEALTH

    E-Print Network [OSTI]

    Krylov, Anna I.

    development, fisheries management, protected-area planning and assessment, and human health issues. Notable related to energy, water, transportation, etc., and help develop strategies for protecting human Courses ENST 387: Economics for Natural Resources and the Environment -- An introduction to the economic

  9. Funding Opportunity: Superfund Hazardous Substance Research and Training Program Sponsor: National Institute of Health

    E-Print Network [OSTI]

    Suzuki, Masatsugu

    Funding Opportunity: Superfund Hazardous Substance Research and Training Program (P42) Sponsor Sciences (NIEHS) is announcing the continuation of the Superfund Hazardous Substance Research and Training techniques for the detection, assessment, and evaluation of the effect on human health of hazardous

  10. Combustion & Health

    E-Print Network [OSTI]

    Hamilton, W.

    2012-01-01T23:59:59.000Z

    ) ? Combustion of fossil fuels for ? Electricity ? Industrial processes ? Vehicle propulsion ? Cooking and heat ? Other ? Munitions ? Fireworks ? Light ? Cigarettes, hookahs? FFCOMBUSTION & HEALTH FFCOMBUSTION: THE THREAT ? SCALE (think health... for public health and strategies to reduce GHG ? Reduce CO2 emissions by 50% by 2030 ? Reduction in PM2.5 deaths greatly offset costs in all models FFCOMBUSTION & HEALTH FFCOMBUSTION: PM EXPOSURE ? Combustion is source of most concern ? Health...

  11. Data driven health system

    E-Print Network [OSTI]

    Rosen Ceruolo, Melissa Beth

    2013-01-01T23:59:59.000Z

    Effective use of data is believed to be the key to address systemic inefficiencies in health innovation and delivery, and to significantly enhance value creation for patients and all stakeholders. However, there is no ...

  12. On the effect of x-ray irradiation on the deformation and fracture behavior of human cortical bone

    SciTech Connect (OSTI)

    Barth, Holly D.; Launey, Maximilien E.; McDowell, Alastair A.; Ager III, Joel W.; Ritchie, Robert O.

    2010-01-10T23:59:59.000Z

    In situ mechanical testing coupled with imaging using high-energy synchrotron x-ray diffraction or tomography imaging is gaining in popularity as a technique to investigate micrometer and even sub-micrometer deformation and fracture mechanisms in mineralized tissues, such as bone and teeth. However, the role of the irradiation in affecting the nature and properties of the tissue is not always taken into account. Accordingly, we examine here the effect of x-ray synchrotron-source irradiation on the mechanistic aspects of deformation and fracture in human cortical bone. Specifically, the strength, ductility and fracture resistance (both work-of-fracture and resistance-curve fracture toughness) of human femoral bone in the transverse (breaking) orientation were evaluated following exposures to 0.05, 70, 210 and 630 kGy irradiation. Our results show that the radiation typically used in tomography imaging can have a major and deleterious impact on the strength, post-yield behavior and fracture toughness of cortical bone, with the severity of the effect progressively increasing with higher doses of radiation. Plasticity was essentially suppressed after as little as 70 kGy of radiation; the fracture toughness was decreased by a factor of five after 210 kGy of radiation. Mechanistically, the irradiation was found to alter the salient toughening mechanisms, manifest by the progressive elimination of the bone's capacity for plastic deformation which restricts the intrinsic toughening from the formation 'plastic zones' around crack-like defects. Deep-ultraviolet Raman spectroscopy indicated that this behavior could be related to degradation in the collagen integrity.

  13. Instructions for use JICA's Assistance in Health

    E-Print Network [OSTI]

    Tsunogai, Urumu

    and clinical care eg, strengthen health systems including the development of human resources, facilitiesInstructions for use #12;1 JICA's Assistance in Health Ryuji MATSUNAGA International Cooperation's Assistance in Health Example of JICA Programme/Projects 2 #12;An Overview of Japan's ODA 3 #12;Japan's ODA

  14. Health and Safety Training Reciprocity

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2014-04-14T23:59:59.000Z

    Establishes a policy for reciprocity of employee health and safety training among DOE entities responsible for employee health and safety at DOE sites and facilities to increase efficiency and effectiveness of Departmental operations while meeting established health and safety requirements. Does not cancel other directives.

  15. Acute Respiratory Health Effects in Asthmatic and Nonasthmatic Children Associated with Short-Term Exposure to Air Pollutants

    E-Print Network [OSTI]

    Irwin, Mark E.

    -Term Exposure to Air Pollutants Author(s): Lisa Kan, Barry Wiggs, Mark Irwin, Irene Yee Source: The CanadianMemorandumof Intenton TransboundaryAir Pollution(1983). Impactassessment-Work Group I. Final Report,Section 4, pp. 1. Environ.Health Perspect.,63, 39-44. Whittemore,A.S., and Korn,E.L. (1980). Asthmaand air pollution

  16. Human Resources Simon Fraser University

    E-Print Network [OSTI]

    Kavanagh, Karen L.

    Human Resources Simon Fraser University Administrative and Professional Staff Job Description A. Identification Position Number: 31482 Position Title: Administrative Assistant (Human Resources Liaison) Name guidance, direction, coordination and effective management and implementation of SFU's Human Resources

  17. A metabolomic investigation of the effects of vitamin E supplementation in humans

    E-Print Network [OSTI]

    Wong, Max; Lodge, John K

    2012-12-19T23:59:59.000Z

    using partial loop mode. The column oven was main- tained at 40°C and the autosampler at 4°C. The mobile Wong and Lodge Nutrition & Metabolism 2012, 9:110 Page 3 of 9 http://www.nutritionandmetabolism.com/content/9/1/110phase consisted of: (A) 0... , Pastor-Barriuso R, Dalal D, Riemersma RA, Appel LJ, Guallar E: Meta-analysis: high-dosage vitamin E supplementation may increase all- cause mortality. Ann Intern Med 2005, 142:37–46. 12. Brigelius-Flohe R: Adverse effects of vitamin E by induction of drug...

  18. Essays on the economics of health insurance

    E-Print Network [OSTI]

    McKnight, Robin

    2002-01-01T23:59:59.000Z

    This thesis brings together three essays on issues in the economics of health insurance. The first study considers the effects of average per-patient caps on Medicare reimbursement for home health care, which took effect ...

  19. Genomic mosaicism in the human brain

    E-Print Network [OSTI]

    Westra, Jurjen Willem

    2008-01-01T23:59:59.000Z

    Zlokovic BV (2008) The blood-brain barrier in health andmosaicism in the human brain ………………………………………. Chapter Threethe Alzheimer’s disease brain ………………………………. Chapter Five DNA

  20. Modulation of rat testes lipid composition by hormones: Effect of PRL (prolactin) and hCG (human chorionic gonadotropin)

    SciTech Connect (OSTI)

    Sebokova, E.; Wierzbicki, A.; Clandinin, M.T. (Univ. of Alberta, Edmonton (Canada))

    1988-10-01T23:59:59.000Z

    The effect of prolactin (PRL) and human chorionic gonadotropin (hCG) administration for 7 days on the composition and function of rat testicular plasma membrane was investigated. Refractory state in Leydig cells desensitized by hCG decreased the binding capacity for {sup 125}I-labeled hCG and also luteinizing hormone (LH)-induced adenosine 3{prime},5{prime}-cyclic monophosphate (cAMP) and testosterone production. In testicular membranes of hCG-treated animals, a depletion of cholesterol and an increase in total phospholipid content was observed after gonadotropin injection, thereby decreasing the cholesterol-to-phospholipid ratio. Injection of high doses of PRL had no effect on the binding capacity or affinity of the LH-hCG receptor but decreased the response of Leydig cells to LH in terms of cAMP and testosterone synthesis. PRL also increased total and esterified cholesterol and decreased free cholesterol and membrane phospholipid content. The fatty acid composition of testicular lipids was significantly and selectively influenced by both hormonal treatments. These observations suggest that metabolism of cholesterol and long-chain polyunsaturated fatty acids in testicular tissue is affected by chorionic gonadotropin and PRL and may provide the mechanism for regulating steroidogenic functions.

  1. Effects of Transcranial Direct Current Stimulation (tDCS) on Human Memory.

    SciTech Connect (OSTI)

    Matzen, Laura E.; Trumbo, Michael Christopher Stefan

    2014-10-01T23:59:59.000Z

    Training a person in a new knowledge base or skill set is extremely time consuming and costly, particularly in highly specialized domains such as the military and the intelligence community. Recent research in cognitive neuroscience has suggested that a technique called transcranial direct current stimulation (tDCS) has the potential to revolutionize training by enabling learners to acquire new skills faster, more efficiently, and more robustly (Bullard et al., 2011). In this project, we tested the effects of tDCS on two types of memory performance that are critical for learning new skills: associative memory and working memory. Associative memory is memory for the relationship between two items or events. It forms the foundation of all episodic memories, so enhancing associative memory could provide substantial benefits to the speed and robustness of learning new information. We tested the effects of tDCS on associative memory, using a real-world associative memory task: remembering the links between faces and names. Working memory refers to the amount of information that can be held in mind and processed at one time, and it forms the basis for all higher-level cognitive processing. We investigated the degree of transfer between various working memory tasks (the N-back task as a measure of verbal working memory, the rotation-span task as a measure of visuospatial working memory, and Raven's progressive matrices as a measure of fluid intelligence) in order to determine if tDCS-induced facilitation of performance is task-specific or general.

  2. Bioinformatics for the human microbiome project

    E-Print Network [OSTI]

    Gevers, Dirk

    Microbes inhabit virtually all sites of the human body, yet we know very little about the role they play in our health. In recent years, there has been increasing interest in studying human-associated microbial communities, ...

  3. Health and Safety Policy Version 2012, Page 1 of 8 Health and Safety Policy

    E-Print Network [OSTI]

    Low, Robert

    Health and Safety Policy Version 2012, Page 1 of 8 Health and Safety Policy #12;Health and Safety Policy Version 2012, Page 2 of 8 Coventry University Health and Safety Policy 1. Introduction, Purpose and Scope The objective of our Health and Safety Policy is to enable the University to operate effectively

  4. Effects of extracellular plaque components on the chlorhexidine sensitivity of strains of Streptococcus mutans and human dental plaque

    SciTech Connect (OSTI)

    Wolinsky, L.E.; Hume, W.R.

    1985-08-01T23:59:59.000Z

    An in vitro study was undertaken to determine the effects of sucrose-derived extracellular plaque components on the sensitivity of selected oral bacteria to chlorhexidine (CX). Cultures of Streptococcus mutans HS-6, OMZ-176, Ingbritt C, 6715-wt13, and pooled human plaque were grown in trypticase soy media with or without 1% sucrose. The sensitivity to CX of bacteria grown in each medium was determined by fixed-time exposure to CX and subsequent measurement of /sup 3/H-thymidine uptake. One-hour exposure to CX at concentrations of 10(-4) M (0.01% w/v) or greater substantially inhibited subsequent cellular division among all the S. mutans strains and human plaque samples tested. An IC50 (the CX concentration which depressed /sup 3/H-thymidine incorporation to 50% of control level) of close to 10(-4) M was noted for S. mutans strains HS-6, OMZ-176, and 6715-wt13 when grown in the presence of sucrose. The same strains grown in cultures without added sucrose showed about a ten-fold greater sensitivity to CX (IC50 close to 10(-5) M). A three-fold difference was noted for S. mutans Ingbritt C. Only a slight increase in the IC50 was noted for the plaque samples cultured in sucrose-containing media, but their threshold for depression of /sup 3/H-thymidine uptake by CX was lower than that for the sucrose-free plaque samples. The study showed that extracellular products confer some protection against CX to the bacteria examined, and provided an explanation for the disparity between clinically-recommended concentrations for plaque suppression and data on in vitro susceptibility.

  5. Antivascular Effects of Neoadjuvant Androgen Deprivation for Prostate Cancer: An In Vivo Human Study Using Susceptibility and Relaxivity Dynamic MRI

    SciTech Connect (OSTI)

    Alonzi, Roberto, E-mail: robertoalonzi@btinternet.com [Marie Curie Research Wing, Mount Vernon Cancer Centre, Northwood (United Kingdom); Padhani, Anwar R.; Taylor, N. Jane [Paul Strickland Scanner Centre, Mount Vernon Cancer Centre, Northwood (United Kingdom); Collins, David J.; D'Arcy, James A. [CRUK and EPSRC Cancer Imaging Centre, Royal Marsden NHS Foundation Trust, Sutton (United Kingdom); Stirling, J. James [Paul Strickland Scanner Centre, Mount Vernon Cancer Centre, Northwood (United Kingdom); Saunders, Michele I.; Hoskin, Peter J. [Marie Curie Research Wing, Mount Vernon Cancer Centre, Northwood (United Kingdom)

    2011-07-01T23:59:59.000Z

    Purpose: The antivascular effects of androgen deprivation have been investigated in animal models; however, there has been minimal investigation in human prostate cancer. This study tested the hypothesis that androgen deprivation causes significant reductions in human prostate tumor blood flow and the induction of hypoxia at a magnitude and in a time scale relevant to the neoadjuvant setting before radiotherapy. Methods and Materials: Twenty patients were examined, each with five multi-parameter magnetic resonance imaging scans: two scans before the commencement of androgen suppression, one scan after 1 month of hormone treatment, and two further scans after 3 months of therapy. Quantitative parametric maps of the prostate informing on relative blood flow (rBF), relative blood volume (rBV), vascular permeability (transfer constant [K{sup trans}]), leakage space (v{sub e}) and blood oxygenation (intrinsic relaxivity [R{sub 2}*]) were calculated. Results: Tumor blood volume and blood flow decreased by 83% and 79%, respectively, in the first month (p < 0.0001), with 74% of patients showing significant changes. The proportion of individual patients who achieved significant changes in T1 kinetic parameter values after 3 months of androgen deprivation for tumor measurements was 68% for K{sup trans} and 53% for v{sub e} By 3 months, significant increases in R{sub 2}* had occurred in prostate tumor, with a rise of 41.1% (p < 0.0001). Conclusions: Androgen deprivation induces profound vascular collapse within 1 month of starting treatment. Increased R{sub 2}* in regions of prostate cancer and a decrease in blood volume suggest a reduction in tumor oxygenation.

  6. Trace-element geochemistry of coal resource development related to environmental quality and health

    SciTech Connect (OSTI)

    Not Available

    1980-01-01T23:59:59.000Z

    This report assesses for decision makers and those involved in coal resource development the environmental and health impacts of trace-element effects arising from significant increases in the use of coal, unless unusual precautions are invoked. Increasing demands for energy and the pressing need for decreased dependence of the United States on imported oil require greater use of coal to meet the nation's energy needs during the next decade. If coal production and consumption are increased at a greatly accelerated rate, concern arises over the release, mobilization, transportation, distribution, and assimilation of certain trace elements, with possible adverse effects on the environment and human health. It is, therefore, important to understand their geochemical pathways from coal and rocks via air, water, and soil to plants, animals, and ultimately humans, and their relation to health and disease. To address this problem, the Panel on Trace Element Geochemistry of Coal Resource Development Related to Health (PECH) was established. Certain assumptions were made by the Panel to highlight the central issues of trace elements and health and to avoid unwarranted duplication of other studies. Based on the charge to the Panel and these assumptions, this report describes the amounts and distribution of trace elements related to the coal source; the various methods of coal extraction, preparation, transportation, and use; and the disposal or recycling of the remaining residues or wastes. The known or projected health effects are discussed at the end of each section.

  7. Why is the drug praziquantel effective in the treatment of parasitic flatworms? Praziquantel (PZQ) is the drug most commonly used in humans and livestock to

    E-Print Network [OSTI]

    Minnesota, University of

    Why is the drug praziquantel effective in the treatment of parasitic flatworms? Praziquantel (PZQ) is the drug most commonly used in humans and livestock to fight the disease schistosomiasis, an infection.S., et al, 1983; Ismail M. et al, 1999). There is evidence that the mechanism of the drug has to do

  8. Activity Recognition for Natural Human Robot Interaction

    E-Print Network [OSTI]

    Ravindran, Balaraman

    Activity Recognition for Natural Human Robot Interaction Addwiteey Chrungoo1 , SS Manimaran between humans and robots. While humans can distinguish between communicative actions and activities of daily living, robots cannot draw such inferences effectively. To allow intuitive human robot interaction

  9. Progress in cadmium-related health effects in persons with high environmental exposure in northwestern Thailand: A five-year follow-up

    SciTech Connect (OSTI)

    Swaddiwudhipong, Witaya, E-mail: swaddi@hotmail.com [Department of Community and Social Medicine, Mae Sot General Hospital, Tak 63110 (Thailand)] [Department of Community and Social Medicine, Mae Sot General Hospital, Tak 63110 (Thailand); Limpatanachote, Pisit [Department of Internal Medicine, Mae Sot General Hospital, Tak 63110 (Thailand)] [Department of Internal Medicine, Mae Sot General Hospital, Tak 63110 (Thailand); Mahasakpan, Pranee [Department of Community and Social Medicine, Mae Sot General Hospital, Tak 63110 (Thailand)] [Department of Community and Social Medicine, Mae Sot General Hospital, Tak 63110 (Thailand); Krintratun, Somyot [Department of Internal Medicine, Mae Sot General Hospital, Tak 63110 (Thailand)] [Department of Internal Medicine, Mae Sot General Hospital, Tak 63110 (Thailand); Punta, Boonyarat; Funkhiew, Thippawan [Department of Community and Social Medicine, Mae Sot General Hospital, Tak 63110 (Thailand)] [Department of Community and Social Medicine, Mae Sot General Hospital, Tak 63110 (Thailand)

    2012-01-15T23:59:59.000Z

    Food-borne cadmium was the principal source of exposure for persons living in the 12 cadmium-contaminated villages in Mae Sot District, Tak Province, northwestern Thailand. This report presents progress in cadmium-related health effects among persons with high cadmium exposure. The study included 436 persons who had urinary cadmium levels {>=}5 {mu}g/g creatinine and were screened for urinary cadmium, renal function, hypertension, diabetes and urinary stones in 2005 (baseline) and 2010 (5-year follow-up). Study renal biomarkers included urinary excretion of {beta}{sub 2}-microglobulin ({beta}{sub 2}-MG), total protein and calcium, serum creatinine and glomerular filtration rate (GFR). The geometric mean level of urinary cadmium statistically significantly reduced from 9.5{+-}1.6 {mu}g/g creatinine in 2005 to 8.8{+-}1.6 {mu}g/g creatinine in 2010. Compared to baseline, the follow-up examination revealed significant increases in urinary {beta}{sub 2}-MG (tubular effect), urinary total protein and serum creatinine, and a decrease in GFR (glomerular effects). Progressive renal dysfunctions were similarly observed in persons both with and without reduction in cadmium intake. Significant increases in prevalence of hypertension, diabetes and urinary stones were also detected at follow-up. These three disorders were found to markedly impair renal functions in the study persons. Our study indicates that in persons with prolonged excessive cadmium exposure, toxic health effects may progress even after exposure reduction. Renal damage from cadmium can be due to its direct nephrotoxic effect and also through the related disorders causing nephropathy.

  10. Scaling up Primary Health Services in Rural Tamil Nadu: Public Investment Requirements and Health Sector Reform

    E-Print Network [OSTI]

    Scaling up Primary Health Services in Rural Tamil Nadu: Public Investment Requirements and Health two key questions in this paper: 1) In terms of state-wide scaling up of rural services in the area of primary health, what will it cost financially and in terms of human resources to scale-up these services

  11. UNO Student Health Services Patient's Bill of Rights and Responsibilities

    E-Print Network [OSTI]

    Kulp, Mark

    health care program. UNO Student Health Services Human Performance Center Rm. 109 (504) 280-6387 wwwUNO Student Health Services Patient's Bill of Rights and Responsibilities Patient's Bill of Rights to the Health Service regarding its operations and the right to change caregivers for any reason. #12;Patient

  12. MSc in Environmental Health The Place of Useful Learning

    E-Print Network [OSTI]

    Mottram, Nigel

    ? Environmental Health is the assessment & management of environmental influences on human health, including study and the corresponding breadth of the degree reflect rapid technological progress. Environmental impact assessmentMSc in Environmental Health The Place of Useful Learning #12;What is Environmental Health

  13. University of Maryland University Health Center

    E-Print Network [OSTI]

    Milchberg, Howard

    special care is taken, should the extracts be lost or damaged, the University Health Center cannot assumeUniversity of Maryland University Health Center ALLERGY INJECTION POLICY The University Health to effectively use our service, we require your cooperation. INSTRUCTIONS Because the University Health Center

  14. Journal of Health & Pollution Vol. 3, No. 5 --June 2013 It is now evident that much more

    E-Print Network [OSTI]

    Mousseau, Timothy A.

    apparent following the 2005 publication of the influential Chernobyl Forum report, in which a large body of literature from Eastern Europe was ignored and an Perspectives on Chernobyl and Fukushima Health Effects outcomes for human populations living downwind from the Chernobyl disaster.1-5 The Chernobyl Forum report

  15. Office of Student Services Health Science Campus MS 1026

    E-Print Network [OSTI]

    Moore, Paul A.

    Avenue Toledo, OH 43614-2598 419-383-5810 BSN Consortium Planning Guide Bowling Green State University College of Health & Human Services Nursing Advisor - Health Center Rm. 102 Bowling Green, OH 43403 419

  16. Health Sciences and Nursing Health Sociology ------------------------------------------------------------------------------------------

    E-Print Network [OSTI]

    Miyashita, Yasushi

    related to health problems and health care systems, through developing and applying theories, concepts44 Health Sciences and Nursing Health Sociology in interdisciplinary academic fields, involving health, medicine and nursing as well as the field of sociology

  17. Health Economics College of Public Health and Health Professions

    E-Print Network [OSTI]

    Kane, Andrew S.

    of health, the demand for health care, health insurance theory, the demand for health insurance, the health insurance market and managed care, the market for physicians' services, production and cost of health care care environment. #12;2 Apply general and health economics concepts and show demonstrated competence

  18. Nitrogen dioxide inside and outside 137 homes and implications for ambient air quality standards and health effects research

    SciTech Connect (OSTI)

    Spengler, J.D.; Duffy, C.P.; Letz, R.; Tibbitts, T.W.; Ferris, B.G. Jr.

    1983-03-01T23:59:59.000Z

    Week-long integrated nitrogen dioxide (NO/sub 2/) measurements made with diffusion tube samplers inside and outside 137 homes in Portage, Wis., over a 1-year period yielded an annual mean ambient NO/sub 2/ concentration of 0.005-0.008 ppm (10-15 micrograms/m/sub 3/). The large variation of NO/sub 2/ concentrations among homes exhibited by this study was likely due to differences in gas stove use, emission rates, and air-exchange rates, limiting the development of prediction models. In addition, this variation reduces the power of epidemiological studies of respiratory health that use ambient NO/sub 2/ concentration levels, a simple dichotomous description of stove type, and two categories of home cooking fuel to describe exposure.

  19. Nitrogen dioxide inside and outside 137 homes and implications for ambient air quality standards and health effects research

    SciTech Connect (OSTI)

    Spengler, J.D.; Duffy, C.P.; Letz, R.; Tibbitts, T.W.; Ferris, B.G. Jr.

    1983-03-01T23:59:59.000Z

    Week-long integrated nitrogen dioxide (NO/sub 2/) measurements made with diffusion tube samples inside and outside 137 homes in Portage, Wisconsin, over a 1-year period yielded an annual mean ambient NO/sub 2/ concentration of 0.005-0.008 ppm. The large variation of NO/sub 2/ concentrations among homes exhibited by this study was likely due to differences in gas stove use, emission rates, and air-exchange rates, limiting the development of prediction models. In addition, this variation reduces the power of epidemiological studies of respiratory health that use ambient NO/sub 2/ concentration levels, a simple dichotomous description of stove type, and two categories of home cooking fuel to describe exposure.

  20. Isoproterenol effects evaluated in heart slices of human and rat in comparison to rat heart in vivo

    SciTech Connect (OSTI)

    Herrmann, Julia E.; Heale, Jason; Bieraugel, Mike; Ramos, Meg [Drug Safety Evaluation, Allergan Inc., 2525 Dupont Dr, Irvine, CA 92612 (United States); Fisher, Robyn L. [Vitron Inc., Tucson, AZ (United States); Vickers, Alison E.M., E-mail: vickers_alison@allergan.com [Drug Safety Evaluation, Allergan Inc., 2525 Dupont Dr, Irvine, CA 92612 (United States)

    2014-01-15T23:59:59.000Z

    Human response to isoproterenol induced cardiac injury was evaluated by gene and protein pathway changes in human heart slices, and compared to rat heart slices and rat heart in vivo. Isoproterenol (10 and 100 ?M) altered human and rat heart slice markers of oxidative stress (ATP and GSH) at 24 h. In this in vivo rat study (0.5 mg/kg), serum troponin concentrations increased with lesion severity, minimal to mild necrosis at 24 and 48 h. In the rat and the human heart, isoproterenol altered pathways for apoptosis/necrosis, stress/energy, inflammation, and remodeling/fibrosis. The rat and human heart slices were in an apoptotic phase, while the in vivo rat heart exhibited necrosis histologically and further progression of tissue remodeling. In human heart slices genes for several heat shock 70 kD members were altered, indicative of stress to mitigate apoptosis. The stress response included alterations in energy utilization, fatty acid processing, and the up-regulation of inducible nitric oxide synthase, a marker of increased oxidative stress in both species. Inflammation markers linked with remodeling included IL-1?, Il-1?, IL-6 and TNF? in both species. Tissue remodeling changes in both species included increases in the TIMP proteins, inhibitors of matrix degradation, the gene/protein of IL-4 linked with cardiac fibrosis, and the gene Ccl7 a chemokine that induces collagen synthesis, and Reg3b a growth factor for cardiac repair. This study demonstrates that the initial human heart slice response to isoproterenol cardiac injury results in apoptosis, stress/energy status, inflammation and tissue remodeling at concentrations similar to that in rat heart slices. - Highlights: • Human response to isoproterenol induced cardiac injury evaluated in heart slices. • Isoproterenol altered apoptosis, energy, inflammation and remodeling pathways. • Human model verified by comparison to rat heart slices and rat heart in vivo. • Human and rat respond to isoproterenol at similar concentrations in vitro.

  1. assessing health worker: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Computer Technologies and Information Sciences Websites Summary: Human health impacts for Renewable Energy scenarios from the EnerGEO Platform of Integrated running the EnerGEO...

  2. Assessing the health risk of solar development on contaminated...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    December 11, 2013 Tweet EmailPrint A recently published report from Argonne's Environmental Science (EVS) division presents a methodology for assessing potential human health...

  3. Effect of Recombinant Human Deoxyribonuclease on Oropharyngeal Secretions in Patients With Head-and-Neck Cancers Treated With Radiochemotherapy

    SciTech Connect (OSTI)

    Mittal, Bharat B., E-mail: bmittal@nmh.org [Department of Radiation Oncology, Northwestern University, Robert H. Lurie Comprehensive Cancer Center, Chicago, Illinois (United States); Wang, Edward [Department of Surgery, Northwestern University, Robert H. Lurie Comprehensive Cancer Center, Chicago, Illinois (United States); Sejpal, Samir [Department of Radiation Oncology, Northwestern University, Robert H. Lurie Comprehensive Cancer Center, Chicago, Illinois (United States); Agulnik, Mark [Section of Medical Oncology, Northwestern University, Robert H. Lurie Comprehensive Cancer Center, Chicago, Illinois (United States); Mittal, Amit [Yale University, New Haven, Connecticut (United States); Harris, Kirk [Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado (United States)

    2013-10-01T23:59:59.000Z

    Purpose: The current study examined the effect of recombinant human deoxyribonuclease (rhDNase) on quality of life (QOL) measures, clinical improvement, and DNA content of thick oropharyngeal secretions (OPS) in patients with head-and-neck (H and N) cancers. Methods and Materials: Thirty-six patients with local-regional advanced H and N cancer receiving chemoradiationtherapy (CRT) were randomized to receive either placebo or rhDNase. Endpoints included MD Anderson Symptom Inventory-Head and Neck (MDASI-HN) and Functional Assessment of Cancer Therapy–Head and Neck (FACT-NH) scores, along with clinical assessment and DNA concentration of OPS. Results: There were no statistically significant differences in patients' QOL outcomes over the study period. Both groups showed an increase in symptom and interference scores, although patients in the rhDNase group showed a greater decline in both scores during the 3 months posttreatment. Similarly, both groups showed a decline in physical and functional well being but recovered in the 3 months posttreatment follow-up, with the rhDNase group exhibiting speedier recovery. Patients in the rhDNase group exhibited significant clinical improvement in OPS, blindly assessed by a physician, compared with the placebo group (67% vs 27%, respectively; P=.046). The rhDNase group showed no change in OPS-DNA concentration, although the placebo group showed a significant increase in DNA concentration during the drug trial (P=.045). There was no differences in acute toxicities between the 2 groups. Conclusions: Our preliminary data suggest that rhDNase did not significantly improve study primary endpoints of QOL measures compared with the placebo group. However, there was a significant improvement in secondary endpoints of clinically assessed OPS and DNA concentration compared with placebo in H and N cancer patients treated with CRT. Further investigation in larger numbers of patients is warranted.

  4. Trichloroacetic acid cycling in Sitka spruce (Picea sitchensis) saplings and the effects on tree health following long term exposure. 

    E-Print Network [OSTI]

    Dickey, Catherine A; Heal, Kate V; Stidson, R T; Koren, R; Cape, Neil; Schröder, V; Heal, Mathew R

    2004-01-01T23:59:59.000Z

    Trichloroacetic acid (TCA, CCl3COOH) has been associated with forest damage but the source of TCA to trees is poorly characterised. To investigate the routes and effects of TCA uptake in conifers, 120 Sitka spruce (Picea ...

  5. Effectiveness of Adult Day Care Programs on Health Outcomes of Thai Family Caregivers of Persons with Dementia

    E-Print Network [OSTI]

    Noimuenwai, Premruetai

    2012-12-31T23:59:59.000Z

    Adult day care (ADC) is recognized as a supportive intervention for persons with dementia (PWD) and family caregivers during the day time. The primary aim of this study was to evaluate the effect of the Thai ADC programs ...

  6. Effects of oncogenic Ras and p38 mitogen-activated protein kinase on the adhesion of normal human cells

    E-Print Network [OSTI]

    Waldman, Lynne K

    2010-01-01T23:59:59.000Z

    Activating mutations in RAS oncogenes commonly arise in human cancers. However, in experimental settings, oncogenic RAS has most often been studied at supraphysiological levels of expression. Importantly, work by others ...

  7. Effects of a second-generation human anti-ErbB2 ImmunoRNase on trastuzumab-resistant tumors and

    E-Print Network [OSTI]

    Raines, Ronald T.

    with antiproliferative activity for trastuzumab-re- sistant cancer cells both in vitro and in vivo that is more potentEffects of a second-generation human anti-ErbB2 ImmunoRNase on trastuzumab-resistant tumors and cardiac cells Chiara D'Avino1,2, Rolando Paciello1,2, Gennaro Riccio1,2, Melina Coppola3, Paolo Laccetti4

  8. Nitrogen dioxide inside and outside 137 homes and implications for ambient air quality standards and health effects research

    SciTech Connect (OSTI)

    Spengler, J.D. (Harvard School of Public Health, Boston, MA); Duffy, C.P.; Letz, R.; Tibbitts, T.W.; Ferris, B.G. Jr.

    1983-03-01T23:59:59.000Z

    Week-long integrated nitrogen dioxide (NO/sub 2/) measurements were made by using diffusion tube samplers inside and outside 137 homes in Portage, WI, over a 1-year period. The annual mean ambient NO/sub 2/ concentrations in this rural community were 10-15 ..mu..g/m/sup 3/. NO/sub 2/ levels inside the kitchens of 112 homes with gas stoves averaged about 50 ..mu..g/m/sup 3/ higher, and bedroom levels were about 30 ..mu..g/m/sup 3/ higher, than outdoor levels. Ten percent of the gas-cooking homes had annual average kitchen NO/sub 2/ levels higher than the National Ambient Air Quality Standard of 100 ..mu..g/m/sup 3/. NO/sub 2/ levels inside kitchens of 25 homes with electric stoves were about two-thirds outdoor levels, while corresponding bedroom levels were one-half outdoor levels. Distinct seasonal patterns (higher indoor levels in winter, lower in summer) consistent with changes in normal air-exchange rates were evident in gas-cooking homes. The large variation of NO/sub 2/ concentrations among homes, likely due to differences in stove use, emission rates, and air-exchange rates, limits the development of prediction models. In addition, this variation would reduce the power of epidemiological studies of respiratory health, which use ambient NO/sub 2/ concentration levels, a simple dichotomous description of stove type and two categories of home cooking fuel to describe exposure.

  9. Fact Sheet HEALTH SCIENCE

    E-Print Network [OSTI]

    Su, Xiao

    · Long Term Care Administrator · Training Coordinator · Clinical Health Education Specialist · Health Media Director · Long Term Care Facilities Manager Fact Sheet HEALTH SCIENCE Highlights · Health Science

  10. DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health

    E-Print Network [OSTI]

    Rau, Don C.

    consequences through its longstanding support for the Maternal-Fetal Medicine Unit and the Neonatal Research and improving the care and treatment of preterm and low birth weight infants, to work with the Office of the NIH-fetal gestations, due in a large part to the increased use of assisted reproductive technologies. Between 1980

  11. DEPARTMENT OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH

    E-Print Network [OSTI]

    Rau, Don C.

    Budget FY 2015 Budget Page No. Organization Chart #12;OAR-3 Institute / Center FY 2013 Actual FY 2014 Enacted FY 2015 President's Budget FY 2015 +/- FY...........................................................................................................................2 Budget Authority by Institute and Center

  12. DEPARTMENT OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH

    E-Print Network [OSTI]

    Bandettini, Peter A.

    Roadmap Initiative has the potential to have a profound and positive impact on how American medical. Because the Roadmap recognizes that one of the most powerful and unifying concepts of 21st century biology central to the research enterprise. Second is the Roadmap's requirement to "re-engineer the national

  13. Department of Health and Human Services National Institutes of Health

    E-Print Network [OSTI]

    Rau, Don C.

    Videocast Website: http://videocast.nih.gov/ Contact Number: 301-594-7232 AGENDA OPEN PORTION - Thursday

  14. Department of Health and Human Services PUBLIC HEALTH SERVICE

    E-Print Network [OSTI]

    Baker, Chris I.

    Committee for Responsible Medicine Jonathan Balcombe, Ph.D., Physicians Committee for Responsible Medicine

  15. Environmental Health Perspectives VOLUME 111 | NUMBER 1 | January 2003 39 National Maps of the Effects of Particulate Matter on Mortality

    E-Print Network [OSTI]

    Dominici, Francesca

    -series studies conducted in the last decade (1,2) have shown that air pollution in many cities in the United are geographically diverse. The National Morbidity Mortality Air Pollution Study (NMMAPS) (3,4) was intended, and national air pollution effects, multistage models were developed (6,7). In the first stage, a separate log

  16. Cellular and molecular research to reduce uncertainties in estimates of health effects from low-level radiation

    SciTech Connect (OSTI)

    Elkind, M.M.; Bedford, J.; Benjamin, S.A.; Waldren, C.A. (Colorado State Univ., Fort Collins, CO (USA)); Gotchy, R.L. (Science Applications International Corp., McLean, VA (USA))

    1990-10-01T23:59:59.000Z

    A study was undertaken by five radiation scientists to examine the feasibility of reducing the uncertainties in the estimation of risk due to protracted low doses of ionizing radiation. In addressing the question of feasibility, a review was made by the study group: of the cellular, molecular, and mammalian radiation data that are available; of the way in which altered oncogene properties could be involved in the loss of growth control that culminates in tumorigenesis; and of the progress that had been made in the genetic characterizations of several human and animal neoplasms. On the basis of this analysis, the study group concluded that, at the present time, it is feasible to mount a program of radiation research directed at the mechanism(s) of radiation-induced cancer with special reference to risk of neoplasia due to protracted, low doses of sparsely ionizing radiation. To implement a program of research, a review was made of the methods, techniques, and instruments that would be needed. This review was followed by a survey of the laboratories and institutions where scientific personnel and facilities are known to be available. A research agenda of the principal and broad objectives of the program is also discussed. 489 refs., 21 figs., 14 tabs.

  17. Health and Safety Policy Statement4 Health and Safety Policy

    E-Print Network [OSTI]

    Haase, Markus

    To achieve this, the University will ensure effective management of risk by setting and reviewing a quality-based health and safety management system and workplace health framework, and by allocating the resources necessary to attain these. It will also define clear management systems and ensure the involvement of all

  18. BENCHMARK DATA FOR STRUCTURAL HEALTH MONITORING Jyrki Kullaa

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    BENCHMARK DATA FOR STRUCTURAL HEALTH MONITORING Jyrki Kullaa Helsinki Metropolia University analysis is a key function in structural health monitoring (SHM). To develop algorithms for SHM, one needs. KEYWORDS : structural health monitoring, damage detection, environmental or operational effects, moving

  19. Health Information Modeling, Simulation, and Analysis: ABMS of HIE Network

    E-Print Network [OSTI]

    Kemner, Ken

    Health Information Exchange Modeling, Simulation, and Analysis: ABMS of HIE Network Opportunity.S. healthcare system would provide a secure, nationwide, interoperable health information infrastructure that connects providers, consumers, and others involved in supporting health and healthcare. Effectively

  20. CDC's National Environmental Public Health Tracking Network NEW MEXICO Keeping Track, Promoting Health

    E-Print Network [OSTI]

    and investigate exposures, to explore linkages between environmental hazards and health outcomes, and to advise of Environmental Hazards and Health Effects #12;The Problem Tracking in Action Improved Public Health Uranium unknowns: Making connections and directing health action The Grants Mineral Belt is high in uranium

  1. Reduction in Work Force Unclassified Staff Office of Human Resources

    E-Print Network [OSTI]

    Howat, Ian M.

    Reduction in Work Force ­ Unclassified Staff 9.15 Office of Human Resources Applies to: Regular by the Health System. Health System employees should contact their human resource department for further information. The Ohio State University ­ Office of Human Resources Page 1 of 1 Policy 9.15 Reduction in Work

  2. Health Physicist

    Broader source: Energy.gov [DOE]

    A successful candidate in this position will serve as a Health Physicist in the Facility Operations Division, Oak Ridge Office of Environmental Management (OREM). The selectee will be regarded as a...

  3. Comparison of the Effects of Carbon Ion and Photon Irradiation on the Angiogenic Response in Human Lung Adenocarcinoma Cells

    SciTech Connect (OSTI)

    Kamlah, Florentine, E-mail: Kamlah@staff.uni-marburg.de [Department of Radiotherapy and Radiooncology, Philipps-University, Marburg (Germany); Haenze, Joerg [Department of Urology and Pediatric Urology, Philipps-University, Marburg (Germany); Arenz, Andrea [Department of Radiotherapy and Radiooncology, Philipps-University, Marburg (Germany); Seay, Ulrike; Hasan, Diya [Department of Internal Medicine II/V, Justus-Liebig-University, Giessen (Germany); Juricko, Janko; Bischoff, Birgit [Department of Radiotherapy and Radiooncology, Philipps-University, Marburg (Germany); Gottschald, Oana R. [Department of Internal Medicine II/V, Justus-Liebig-University, Giessen (Germany); Fournier, Claudia; Taucher-Scholz, Gisela; Scholz, Michael [GSI Helmholtzzentrum fuer Schwerionenforschung, Darmstadt (Germany); Seeger, Werner [Department of Internal Medicine II/V, Justus-Liebig-University, Giessen (Germany); Engenhart-Cabillic, Rita [Department of Radiotherapy and Radiooncology, Philipps-University, Marburg (Germany); Department of Radiotherapy, Justus-Liebig-University, Giessen (Germany); Rose, Frank [Department of Radiotherapy and Radiooncology, Philipps-University, Marburg (Germany)

    2011-08-01T23:59:59.000Z

    Purpose: Radiotherapy resistance is a commonly encountered problem in cancer treatment. In this regard, stabilization of endothelial cells and release of angiogenic factors by cancer cells contribute to this problem. In this study, we used human lung adenocarcinoma (A549) cells to compare the effects of carbon ion and X-ray irradiation on the cells' angiogenic response. Methods and Materials: A549 cells were irradiated with biologically equivalent doses for cell survival of either carbon ions (linear energy transfer, 170 keV/{mu}m; energy of 9.8 MeV/u on target) or X-rays and injected with basement membrane matrix into BALB/c nu/nu mice to generate a plug, allowing quantification of angiogenesis by blood vessel enumeration. The expression of angiogenic factors (VEGF, PlGF, SDF-1, and SCF) was assessed at the mRNA and secreted protein levels by using real-time reverse transcription-PCR and enzyme-linked immunosorbent assay. Signal transduction mediated by stem cell factor (SCF) was assessed by phosphorylation of its receptor c-Kit. For inhibition of SCF/c-Kit signaling, a specific SCF/c-Kit inhibitor (ISCK03) was used. Results: Irradiation of A549 cells with X-rays (6 Gy) but not carbon ions (2 Gy) resulted in a significant increase in blood vessel density (control, 20.71 {+-} 1.55; X-ray, 36.44 {+-} 3.44; carbon ion, 16.33 {+-} 1.03; number per microscopic field). Concordantly, irradiation with X-rays but not with carbon ions increased the expression of SCF and subsequently caused phosphorylation of c-Kit in endothelial cells. ISCK03 treatment of A549 cells irradiated with X-rays (6 Gy) resulted in a significant decrease in blood vessel density (X-ray, 36.44 {+-} 3.44; X-ray and ISCK03, 4.33 {+-} 0.71; number of microscopic field). These data indicate that irradiation of A549 cells with X-rays but not with carbon ions promotes angiogenesis. Conclusions: The present study provides evidence that SCF is an X-ray-induced mediator of angiogenesis in A549 cells, a phenomenon that could not be observed with carbon ion irradiation. Thus, in this model system evaluating angiogenesis, carbon ion irradiation may have a therapeutic advantage. This observation should be confirmed in orthotopic lung tumor models.

  4. An exploration of the effectiveness of artificial mini-magnetospheres as a potential Solar Storm shelter for long term human space missions

    E-Print Network [OSTI]

    Bamford, Ruth; Bradford, John; Todd, Tom N; Stafford-Allen, Robin; Alves, E Paulo; Silva, Luis; Collingwood, Cheryl; Crawford, Ian A; Bingham, Robert

    2014-01-01T23:59:59.000Z

    In this paper we explore the effectiveness of an artificial mini-magnetosphere as a potential radiation shelter for long term human space missions. Our study includes the differences that the plasma environment makes to the efficiency of the shielding from the high energy charged particle component of solar and cosmic rays, which radically alters the power requirements. The incoming electrostatic charges are shielded by fields supported by the self captured environmental plasma of the solar wind, potentially augmented with additional density. The artificial magnetic field generated on board acts as the means of confinement and control. Evidence for similar behaviour of electromagnetic fields and ionised particles in interplanetary space can be gained by the example of the enhanced shielding effectiveness of naturally occurring "mini-magnetospheres" on the moon. The shielding effect of surface magnetic fields of the order of ~100s nanoTesla is sufficient to provide effective shielding from solar proton bombard...

  5. THE UNIVERSITY Of TENNESSEE Health Science Center

    E-Print Network [OSTI]

    Cui, Yan

    THE UNIVERSITY Of TENNESSEE Health Science Center Human Resources 910 Madison Ave, Suite 722 Memphis, TN 38163 Tel: (901) 448-5600 Fax: (901) 448-5170 THE UNIVERSITY OF TENNESSEE HEALTH SCIENCE the Personnel Records of UT public domain. This gives any citizen of the State of Tennessee the right to view

  6. Office of Domestic and International Health Studies

    Broader source: Energy.gov [DOE]

    The Office of Domestic and International Health Studies engages in the conduct of international scientific studies that may provide new knowledge and information about the human response to ionizing radiation in the workplace or people exposed in communities as a result of nuclear accidents, including providing health and environmental monitoring services to populations specified by law.

  7. REPORT NO. 3 health implications

    E-Print Network [OSTI]

    REPORT NO. 3 health implications of fallout from nuclear weapons testing through 1961 May 1962 on radiation doses and possible health effects of atmospheric nuclear weapons testing. Before discussing weapons testing through 1961 May1962 Report of the FEDERAL RADIATION COUNCIL For sale

  8. Global Health Research | 2 Global Health Research

    E-Print Network [OSTI]

    Rambaut, Andrew

    Global Health Research | 2 Global Health Research Supporting researchers in low- and middle-income countries to carry out health- related research within their own countries. Gl bal Health #12;3 | Global Health Research #12;Global Health Research | 4 We are a global charitable foundation dedicated

  9. HEALTH ECONOMICS Health Econ. (in press)

    E-Print Network [OSTI]

    Scharfstein, Daniel

    health services/economics; costs and cost analysis; health services/utilization; quality of health careHEALTH ECONOMICS Health Econ. (in press) Published online in Wiley InterScience (www and ROBERT BLACKb a Department of Population and Family Health Sciences, Johns Hopkins Bloomberg School

  10. College of Health Sciences Health Sciences Connection

    E-Print Network [OSTI]

    Barrash, Warren

    "--today we hear that word bantered about more than ever. Whether the context is national (health care reformCollege of Health Sciences Health Sciences Connection 1 Dean's Message College of Health Sciences Health Sciences Connection March 2010 Volume VIII (7) Greetings health sciences' colleagues, community

  11. College of Health Sciences Health Sciences Connection

    E-Print Network [OSTI]

    Barrash, Warren

    with a variety of topics including substance abuse, worksite health promotion, health care cost containment the importance of health care as well as the promotion, protection and maintenance of health. Without a doubt things in the area of health promotion and health care. As the COHS look to the future, we need to take

  12. Status of health and environmental research relative to direct coal liquefaction: 1976 to the present

    SciTech Connect (OSTI)

    Gray, R.H.; Cowser, K.E. (eds.)

    1982-06-01T23:59:59.000Z

    This document describes the status of health and environmental research efforts, supported by the US Department of Energy (DOE), to assist in the development of environmentally acceptable coal liquefaction processes. Four major direct coal liquefaction processes are currently in (or have been investigated at) the pilot plant stage of development. Two solvent refined coal processes (SRC-I and -II), H-coal (a catalytic liquefaction process) and Exxon donor solvent (EDS). The Pacific Northwest Laboratory was assigned responsibility for evaluating SRC process materials and prepared comprehensive health and environmental effects research program plans for SRC-I and -II. A similar program plan was prepared for H-coal process materials by the Oak Ridge National Laboratory. A program has been developed for EDS process materials by Exxon Research and Engineering Co. The program includes short-term screening of coal-derived materials for potential health and ecological effects. Longer-term assays are used to evaluate materials considered most representative of potential commercial practice and with greatest potential for human exposure or release to the environment. Effects of process modification, control technologies and changing operational conditions on potential health and ecological effects are also being evaluated. These assessments are being conducted to assist in formulating cost-effective environmental research programs and to estimate health and environmental risks associated with a large-scale coal liquefaction industry. Significant results of DOE's health and environmental research efforts relative to coal liquefaction include the following: chemical characterization, health effects, ecological fate and effects, amelioration and risk assessment.

  13. Linking coral reef health and human welfare

    E-Print Network [OSTI]

    Walsh, Sheila Marie

    2009-01-01T23:59:59.000Z

    Baselines and degradation of coral reefs in the northernBaselines and degradation of coral reefs in the northern2006) Fisheries Resources: Coral ReefFishes. Solomon Islands

  14. Linking coral reef health and human welfare

    E-Print Network [OSTI]

    Walsh, Sheila Marie

    2009-01-01T23:59:59.000Z

    create a balanced factorial design. An additional 13 sitesa balanced natural factorial experimental design to test theusing a natural factorial experimental design (Fig. 1-1),

  15. Health and Safety Research Division progress report for the period April 1, 1990--September 30, 1991

    SciTech Connect (OSTI)

    Kaye, S.V.

    1992-03-01T23:59:59.000Z

    This is a brief progress report from the Health and Safety Research Division of Oak Ridge National Laboratory. Information is presented in the following sections: Assessment Technology including Measurement Applications and Development, Pollutant Assessments, Measurement Systems Research, Dosimetry Applications Research, Metabolism and Dosimetry Research and Nuclear Medicine. Biological and Radiation Physics including Atomic, Molecular, and High Voltage Physics, Physics of Solids and Macromolecules, Liquid and Submicron Physics, Analytic Dosimetry and Surface Physics and Health Effects. Chemical Physics including Molecular Physics, Photophysics and Advanced Monitoring Development. Biomedical and Environmental Information Analysis including Human Genome and Toxicology, Chemical Hazard Evaluation and Communication, Environmental Regulations and Remediation and Information Management Technology. Risk Analysis including Hazardous Waste.

  16. Protecting Patients, Preserving Integrity, Advancing Health

    E-Print Network [OSTI]

    Chapman, Michael S.

    values of protecting the integrity of their research, the well being of the human subjects whoProtecting Patients, Preserving Integrity, Advancing Health: Accelerating the Implementation of COI of Interest in Human Subjects Research February 2008 #12;Protecting Patients, Preserving Integrity, Advancing

  17. Allergy arising from exposure to airborne contaminants in an insect rearing facility: Health effects and exposure control

    SciTech Connect (OSTI)

    Wolff, D.

    1994-06-01T23:59:59.000Z

    In agricultural crop improvement, yield under various stress conditions and limiting factors is assessed experimentally. Of the stresses on plants which affect yield are those due to insects. Ostrinia nubilalis, the European corn borer (corn borer) is a major pest in sweet and field corn in the U.S. There are many ways to fight crop pests such as the corn borer, including (1) application of chemical insecticides, (2) application of natural predators and, (3) improving crop resistance through plant genetics programs. Randomized field trials are used to determine the effectiveness of pest management programs. These trials frequently consist of randomly selected crop plots to which well-defined input regimes are instituted. For example, corn borers might be released onto crop plots in several densities at various stages of crop development, then sprayed with different levels of pesticide. These experiments are duplicated across regions and, in some cases across the country, to determine, in this instance for example, the best pesticide application rate for a given pest density and crop development stage. In order to release these pests onto crop plots, one must have an adequate supply of the insect pest. In winter months studies are carried out in the laboratory to examine chemical and natural pesticide effectiveness, as well as such things as the role of pheromones in moth behavior. The advantage in field trials is that yield data can be garnered directly. In this country, insects are raised for crop research primarily through the US Department of Agriculture, in cooperation with public Land Grant Universities and, by the private sector agricultural concerns - seed companies and others. This study quantifies the airborne allergen exposure of persons working in a Land Grant University entomology lab were allergy to European corn borer was suspected.

  18. _____________________________ Environment, Health, & Safety _________ __________________ Training Program

    E-Print Network [OSTI]

    Eisen, Michael

    _________ __________________ Training Program EHS 0368 Asbestos Class III Refresher Course Syllabus Subject Category: Occupational · Recognize the health effects associated with asbestos, and measure used to control exposure · Identify work practices and controls for incidental disturbance of asbestos containing building materials. Course

  19. Superfund Cleanups and Infant Health

    E-Print Network [OSTI]

    Currie, Janet

    2011-02-23T23:59:59.000Z

    We are the first to examine the effect of Superfund cleanups on infant health rather than focusing on proximity to a site. We study singleton births to mothers residing within 5km of a Superfund site between 1989 and 2003 ...

  20. Employment as a Health Determinant for Working-age, Dually-eligible People with Disabilities

    E-Print Network [OSTI]

    Hall, Jean P.; Kurth, Noelle K.; Hunt, Suzanne L.

    2013-04-01T23:59:59.000Z

    Background: Individuals with disabilities are a health disparity population with high rates of risk factors, lower overall health status, and greater health care costs. The interacting effect of employment, health and disability has not been...

  1. Laboratory for Energy-Related Health Research (LEHR) University of California at Davis, California. Final report

    SciTech Connect (OSTI)

    NONE

    1997-09-01T23:59:59.000Z

    This Annual Site Environmental Report for the Laboratory for Energy-Related Health Research (LEHR) Site (the Site) includes 1996 environmental monitoring data for Site air, soil, ground water, surface water, storm water and ambient radiation. DOE operation of LEHR as a functioning research location ceased in 1989, after the completion of three decades of research on the health effects of low-level radiation exposure (primarily strontium-90 and radium-226), using beagles to simulate effects on human health. During 1996, the U.S. Department of Energy (DOE) conducted activities at the Site in support of Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) Environmental remediation and the decontamination and decommissioning (D&D) of Site buildings. Extensive environmental data were collected in 1996 to evaluate appropriate remedial actions for the Site.

  2. Design and evaluation of a quasi-passive robotic knee brace : on the effects of parallel elasticity on human running

    E-Print Network [OSTI]

    Elliott, Grant (Grant Andrew)

    2012-01-01T23:59:59.000Z

    While the effects of series compliance on running biomechanics are documented, the effects of parallel compliance are known only for the simpler case of hopping. As many practical exoskeleton and orthosis designs act in ...

  3. OccupationalSafety andHealthResearchCenter

    E-Print Network [OSTI]

    Beex, A. A. "Louis"

    Disorders, Safety, Slips/Trips/Falls, Work Organization w w w.oshrc.ic tas.vt.edu Separating humans from the safety and health of workers. OSHRC, formally known as the Center for Innova- tion in Construction Safety for Occupational Safety and Health (NIOSH) to innova- tively improve health and safety in the construction sector

  4. CERTIFICATION OF HEALTH CARE PROVIDER FOR EMPLOYEE'S PREGNANCY DISABILITY

    E-Print Network [OSTI]

    Eirinaki, Magdalini

    CERTIFICATION OF HEALTH CARE PROVIDER FOR EMPLOYEE'S PREGNANCY DISABILITY HUMAN RESOURCES Employee this form to your medical provider. Section II must be fully completed by the health care provider Department/College name: Campus Phone: I authorize my health care provider to complete this form and provide

  5. Poor Nutrition and Health Concerns in Low Income Population

    E-Print Network [OSTI]

    and foodborne illness, reduced indigent health care costs and improved quality of life. Contact: Dean McPoor Nutrition and Health Concerns in Low Income Population An estimated one out of every six in 1995 as a cooperative endeavor among the Texas A&M AgriLife Extension Service, Texas Health and Human

  6. The Effects of Degraded Digital Instrumentation and Control Systems on Human-system Interfaces and Operator Performance: HFE Review Guidance and Technical Basis

    SciTech Connect (OSTI)

    O'Hara, J.M.; W. Gunther, G. Martinez-Guridi

    2010-02-26T23:59:59.000Z

    New and advanced reactors will use integrated digital instrumentation and control (I&C) systems to support operators in their monitoring and control functions. Even though digital systems are typically highly reliable, their potential for degradation or failure could significantly affect operator performance and, consequently, impact plant safety. The U.S. Nuclear Regulatory Commission (NRC) supported this research project to investigate the effects of degraded I&C systems on human performance and plant operations. The objective was to develop human factors engineering (HFE) review guidance addressing the detection and management of degraded digital I&C conditions by plant operators. We reviewed pertinent standards and guidelines, empirical studies, and plant operating experience. In addition, we conducted an evaluation of the potential effects of selected failure modes of the digital feedwater system on human-system interfaces (HSIs) and operator performance. The results indicated that I&C degradations are prevalent in plants employing digital systems and the overall effects on plant behavior can be significant, such as causing a reactor trip or causing equipment to operate unexpectedly. I&C degradations can impact the HSIs used by operators to monitor and control the plant. For example, sensor degradations can make displays difficult to interpret and can sometimes mislead operators by making it appear that a process disturbance has occurred. We used the information obtained as the technical basis upon which to develop HFE review guidance. The guidance addresses the treatment of degraded I&C conditions as part of the design process and the HSI features and functions that support operators to monitor I&C performance and manage I&C degradations when they occur. In addition, we identified topics for future research.

  7. College of Health Sciences Health Sciences Connection

    E-Print Network [OSTI]

    Barrash, Warren

    , College of Health Sciences. · "Innovative Ways to Address Idaho's Healthcare Needs: Long-Term CareCollege of Health Sciences Health Sciences Connection 1 Dean's Message College of Health Sciences Health Sciences Connection February 2011 Volume IX (3) Since the last COHS newsletter, the faculty

  8. Students' Health Service Hampton House Health Centre

    E-Print Network [OSTI]

    Bristol, University of

    .bristol.ac.uk/infectious-diseases/meningitis www.bristol.ac.uk/infectious-diseases/mumps www.bristol.ac.uk/infectious-diseases/measles. Health care / Health care Student support Health care Registering with a doctor It is important that you register' Health Service The Students' Health Service (SHS) offers full general practice care, including: ·travel

  9. College of Health Sciences Health Sciences Connection

    E-Print Network [OSTI]

    Barrash, Warren

    today. In politics, in education, in health care, in society in general we are so turned inwardCollege of Health Sciences Health Sciences Connection 1 Dean's Message College of Health Sciences Health Sciences Connection April/May 2010 Volume VIII (8) WOW! Spring semester of 2010 is almost

  10. College of Health Sciences Health Sciences Connection

    E-Print Network [OSTI]

    Barrash, Warren

    College of Health Sciences Health Sciences Connection 1 Dean's Message College of Health Sciences Health Sciences Connection April 2011 Volume IX (4) The end of the spring semester is quickly approaching accreditation review. Similarly, the Environmental and Occupational Health program also had a very positive

  11. Biological and Physical Assessment of Streams in Northern California: Evaluating the Effects of Global Change and Human Disturbance

    E-Print Network [OSTI]

    Lawrence, Justin Earl

    2011-01-01T23:59:59.000Z

    Key words: climate change, mediterranean streams, benthicthe effects of climate change on Mediterranean streams andeffects of climate change in mediterranean-climate streams

  12. Effects of the differentiated keratinocyte phenotype on expression levels of CYP1-4 family genes in human skin cells

    SciTech Connect (OSTI)

    Du Liping [Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232 (United States); Neis, Mark M. [Department of Dermatology and Allergology, University Hospital of the RWTH, Aachen (Germany); Ladd, Patricia A. [Department of Medicine/Dermatology, Vanderbilt University School of Medicine, Nashville, TN 37232 (United States); Lanza, Diane L. [Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, UT 84112 (United States); Yost, Garold S. [Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, UT 84112 (United States); Keeney, Diane S. [VA Tennessee Valley Healthcare System, Nashville, TN 37212 (United States) and Department of Medicine/Dermatology, Vanderbilt University School of Medicine, Nashville, TN 37232 (United States) and Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232 (United States)]. E-mail: diane.keeney@vanderbilt.edu

    2006-06-01T23:59:59.000Z

    Epoxyeicosatrienoic acids produced by mouse CYP2B19 have been implicated in mechanisms regulating epidermal cornification (Ladd, P.A., Du, L., Capdevila, J.H., Mernaugh, R., Keeney, D.S., 2003. Epoxyeicosatrienoic acids activate transglutaminases in situ and induce cornification of epidermal keratinocytes. J. Biol. Chem. 278, 35184-35192). In this study, we aimed to identify CYPs that are up-regulated during keratinocyte differentiation and potentially responsible for epoxyeicosatrienoic acid formation in human skin. The cellular differentiation state of human epidermal cell cultures was manipulated to resemble the basal, spinous, and granular cell phenotypes in vivo. Changes in CYP mRNA levels were measured as a function of differentiation state for a panel of 15 CYPs that included known and putative arachidonate monooxygenases. Quantitative real-time PCR analyses showed that all of the CYPs were expressed in differentiating epidermal cell cultures and in human epidermis, with the exception of CYP2B6, which was poorly expressed in vitro. Six CYPs were strongly up-regulated at Day 6 and Day 8 of in vitro differentiation (CYP4B1, 2W1, 2C18, 3A4, 2C19, 2C9); the increase in mRNA levels ranged from 27- to 356-fold. Only CYP2U1 mRNA levels decreased (6-fold change) during cellular differentiation. Six CYPs showed little variation (<2-fold change) in mRNA levels during in vitro differentiation (CYP2S1, 2J2, 1B1, 1A1, 2E1, 2D6). No single CYP was identifiable as being a functional counterpart to CYP2B19 in mouse skin since none qualified as being mainly responsible for epidermal epoxyeicosatrienoic acid formation. Rather, the data suggest that epoxyeicosatrienoic acids in human skin are formed by several CYPs expressed in different cell layers of the epidermis. This would predict that CYP-derived eicosanoids have different functions in different epidermal cell layers.

  13. Health Effects | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742 33Frequently20,000 RussianBy: Thomas P. D'Agostino,GlenLearning andDesign in EMHazelU.S. Department

  14. Integrating Human Indoor Air Pollutant Exposure within Life Cycle Impact Assessment

    SciTech Connect (OSTI)

    Hellweg, Stefanie; Demou, Evangelia; Bruzzi, Raffaella; Meijer, Arjen; Rosenbaum, Ralph K.; Huijbregts, Mark A.J.; McKone, Thomas E.

    2008-12-21T23:59:59.000Z

    Neglecting health effects from indoor pollutant emissions and exposure, as currently done in Life Cycle Assessment (LCA), may result in product or process optimizations at the expense of workers? or consumers? health. To close this gap, methods for considering indoor exposure to chemicals are needed to complement the methods for outdoor human exposure assessment already in use. This paper summarizes the work of an international expert group on the integration of human indoor and outdoor exposure in LCA, within the UNEP/SETAC Life Cycle Initiative. A new methodological framework is proposed for a general procedure to include human-health effects from indoor exposure in LCA. Exposure models from occupational hygiene and household indoor air quality studies and practices are critically reviewed and recommendations are provided on the appropriateness of various model alternatives in the context of LCA. A single-compartment box model is recommended for use as a default in LCA, enabling one to screen occupational and household exposures consistent with the existing models to assess outdoor emission in a multimedia environment. An initial set of model parameter values was collected. The comparison between indoor and outdoor human exposure per unit of emission shows that for many pollutants, intake per unit of indoor emission may be several orders of magnitude higher than for outdoor emissions. It is concluded that indoor exposure should be routinely addressed within LCA.

  15. Interactive toxicity of inorganic mercury and trichloroethylene in rat and human proximal tubules: Effects on apoptosis, necrosis, and glutathione status

    SciTech Connect (OSTI)

    Lash, Lawrence H. [Department of Pharmacology, Wayne State University School of Medicine, 540 East Canfield Avenue, Detroit, MI 48201 (United States)]. E-mail: l.h.lash@wayne.edu; Putt, David A. [Department of Pharmacology, Wayne State University School of Medicine, 540 East Canfield Avenue, Detroit, MI 48201 (United States); Hueni, Sarah E. [Department of Pharmacology, Wayne State University School of Medicine, 540 East Canfield Avenue, Detroit, MI 48201 (United States); Payton, Scott G. [Department of Pharmacology, Wayne State University School of Medicine, 540 East Canfield Avenue, Detroit, MI 48201 (United States); Zwickl, Joshua [Department of Pharmacology, Wayne State University School of Medicine, 540 East Canfield Avenue, Detroit, MI 48201 (United States)

    2007-06-15T23:59:59.000Z

    Simultaneous or prior exposure to one chemical may alter the concurrent or subsequent response to another chemical, often in unexpected ways. This is particularly true when the two chemicals share common mechanisms of action. The present study uses the paradigm of prior exposure to study the interactive toxicity between inorganic mercury (Hg{sup 2+}) and trichloroethylene (TRI) or its metabolite S-(1,2-dichlorovinyl)-L-cysteine (DCVC) in rat and human proximal tubule. Pretreatment of rats with a subtoxic dose of Hg{sup 2+} increased expression of glutathione S-transferase-{alpha}1 (GST{alpha}1) but decreased expression of GST{alpha}2, increased activities of several GSH-dependent enzymes, and increased GSH conjugation of TRI. Primary cultures of rat proximal tubular (rPT) cells exhibited both necrosis and apoptosis after incubation with Hg{sup 2+}. Pretreatment of human proximal tubular (hPT) cells with Hg{sup 2+} caused little or no changes in GST expression or activities of GSH-dependent enzymes, decreased apoptosis induced by TRI or DCVC, but increased necrosis induced by DCVC. In contrast, pretreatment of hPT cells with TRI or DCVC protected from Hg{sup 2+} by decreasing necrosis and increasing apoptosis. Thus, whereas pretreatment of hPT cells with Hg{sup 2+} exacerbated cellular injury due to TRI or DCVC by shifting the response from apoptosis to necrosis, pretreatment of hPT cells with either TRI or DCVC protected from Hg{sup 2+}-induced cytotoxicity by shifting the response from necrosis to apoptosis. These results demonstrate that by altering processes related to GSH status, susceptibilities of rPT and hPT cells to acute injury from Hg{sup 2+}, TRI, or DCVC are markedly altered by prior exposures.

  16. Global Health Seminar Series

    E-Print Network [OSTI]

    Klein, Ophir

    Bay Area Global Health Seminar Series Moving beyond millennium targets in global health: The challenges of investing in health and universal health coverage Although targets can help to focus global health efforts, they can also detract attention from deeper underlying challenges in global health

  17. The effects of waist-to-hip ratio and body weight on male judgements of female physical attractiveness, wife desirability, and health, both within and between cultures. 

    E-Print Network [OSTI]

    McLean, Julia

    2007-01-01T23:59:59.000Z

    Evolutionary theories maintain that female physical attractiveness has evolved to honestly signal health and reproductive potential. Both a low waist-to-hip ratio (WHR) and a critical range of body weight have received ...

  18. Health Benefits of Particle Filtration

    SciTech Connect (OSTI)

    Fisk, William J.

    2013-10-01T23:59:59.000Z

    The evidence of health benefits of particle filtration in homes and commercial buildings is reviewed. Prior reviews of papers published before 2000 are summarized. The results of 16 more recent intervention studies are compiled and analyzed. Also, reviewed are four studies that modeled health benefits of using filtration to reduce indoor exposures to particles from outdoors. Prior reviews generally concluded that particle filtration is, at best, a source of small improvements in allergy and asthma health effects; however, many early studies had weak designs. A majority of recent intervention studies employed strong designs and more of these studies report statistically significant improvements in health symptoms or objective health outcomes, particularly for subjects with allergies or asthma. The percent age improvement in health outcomes is typically modest, for example, 7percent to 25percent. Delivery of filtered air to the breathing zone of sleeping allergic or asthmatic persons may be more consistently effective in improving health than room air filtration. Notable are two studies that report statistically significant improvements, with filtration, in markers that predict future adverse coronary events. From modeling, the largest potential benefits of indoor particle filtration may be reductions in morbidity and mortality from reducing indoor exposures to particles from outdoor air.

  19. Health Benefits of Particle Filtration

    SciTech Connect (OSTI)

    Fisk, William J.

    2013-10-01T23:59:59.000Z

    The evidence of health benefits of particle filtration in homes and commercial buildings is reviewed. Prior reviews of papers published before 2000 are summarized. The results of 16 more recent intervention studies are compiled and analyzed. Also reviewed are four studies that modeled health benefits of using filtration to reduce indoor exposures to particles from outdoors. Prior reviews generally concluded that particle filtration is, at best, a source of small improvements in allergy and asthma health effects; however, many early studies had weak designs. A majority of recent intervention studies employed strong designs and more of these studies report statistically significant improvements in health symptoms or objective health outcomes, particularly for subjects with allergies or asthma. The percentage improvement in health outcomes is typically modest, e.g., 7percent to 25percent. Delivery of filtered air to the breathing zone of sleeping allergic or asthmatic persons may be more consistently effective in improving health than room air filtration. Notable are two studies that report statistically significant improvements, with filtration, in markers that predict future adverse coronary events. From modeling, the largest potential benefits of indoor particle filtration may be reductions in morbidity and mortality from reducing indoor exposures to particles from outdoor air.

  20. Human Resources 413 Academy Street Newark, Delaware 19716

    E-Print Network [OSTI]

    Firestone, Jeremy

    Options and Your Health Coverage." The health care reform law known as the Affordable Care Act ("ACA Information When key parts of the health care law take effect in 2014, there will be a new way to buy health.udel.edu/hr September 27, 2013 Dear Colleague: Attached is a Notice entitled "New Health Insurance Marketplace Coverage

  1. Students' Health Service Hampton House Health Centre

    E-Print Network [OSTI]

    Bristol, University of

    .ac.uk/infectious-diseases. Health care / Student support Other NHS services NHS 111 NHS 111 is a telephone service, giving in an emergency. Student support / Health care Student support Health care Registering with a doctor practice care, including: · travel immunisation and advice · contraceptive advice · sexual health testing

  2. Annual Women's Health Forum Global Women's Health

    E-Print Network [OSTI]

    Kay, Mark A.

    5th Annual Women's Health Forum Global Women's Health Hosted by The Stanford WSDM* Center May 21;3 Welcome to the 5th Annual Women's Health Forum - hosted by the Stanford WSDM Center, also known as the Stanford Center for Health Research on Women and Sex Differences in Medicine. The Stanford WSDM Center

  3. College of Health Sciences Health Sciences Connection

    E-Print Network [OSTI]

    Barrash, Warren

    College of Health Sciences Health Sciences Connection 1 Dean's Message College of Health Sciences Health Sciences Connection December 2009 January 2010 Volume VIII (5) Moving from the Superficial the superficial level so that the result is the formation of deep relationships, caring, compassion, justice, love

  4. Center for Health & Counseling Services Health Services

    E-Print Network [OSTI]

    Rainforth, Emma C.

    College How is West Nile diagnosed? If a health care provider suspects WNV, samples of the patient's bloodCenter for Health & Counseling Services Health Services 505 Ramapo Valley Road, Mahwah, NJ 07430 Nile Virus outbreak is the biggest since the virus was first identified in the United States, health

  5. College of Health Sciences Health Sciences Connection

    E-Print Network [OSTI]

    Barrash, Warren

    the sweeping changes associated with health care reform. Health care reform represents the most significant health care legislation since the development of Medicare and Medicaid in 1965. It has tremendous potential ramification for the future of our college. Health care reform will dramatically increase

  6. Utah Department of Health Bureau of Health Facility Licensing, Certification and Resident Assessment

    E-Print Network [OSTI]

    Tipple, Brett

    Utah Department of Health Bureau of Health Facility Licensing, Certification and Resident of Utah Rule R432-31 (http://health.utah.gov/hflcra/forms.php) This is a physician order sheet based be effectively managed at current setting. ___ Limited additional interventions: Includes care above. May also

  7. Bachelor of Science, Environmental and Occupational Health, 2014-2015 Name ID# Date

    E-Print Network [OSTI]

    Barrash, Warren

    Bachelor of Science, Environmental and Occupational Health, 2014-2015 Name ID# Date General Degree and Humanities 3-4 DLS ENGL 202 Technical Communication 3 DLS ENVHLTH 102 Global Environmental Health 3 BIOL 192 320 Community Environmental Health Management ENVHLTH 415 Occupational Safety and Health ENVHLTH 416

  8. Bachelor of Science, Environmental and Occupational Health, 2013-2014 Name ID# Date

    E-Print Network [OSTI]

    Barrash, Warren

    Bachelor of Science, Environmental and Occupational Health, 2013-2014 Name ID# Date General Degree and Humanities 3-4 DLS ENGL 202 Technical Communication 3 DLS ENVHLTH 102 Global Environmental Health 3 BIOL 192 320 Community Environmental Health Management ENVHLTH 415 Occupational Safety and Health ENVHLTH 416

  9. Bachelor of Science, Environmental and Occupational Health, 2012-2013 Name ID# Date

    E-Print Network [OSTI]

    Barrash, Warren

    Bachelor of Science, Environmental and Occupational Health, 2012-2013 Name ID# Date General Degree and Humanities 3-4 DLS ENGL 202 Technical Communication 3 DLS ENVHLTH 102 Global Environmental Health 3 BIOL 192 Management ENVHLTH 320 Community Environmental Health Management ENVHLTH 415 Occupational Safety and Health

  10. The emerging role and benefits of boundary analysis in spatio-temporal epidemiology and public health

    E-Print Network [OSTI]

    to study human health outcomes, correlates and determinants. Epidemiology has a strong clinical tradition-time change; health outcomes; environmental exposures; health-environment association 1. Introduction of the ingredients of living that are determinants of individual health status and outcomes. From this perspective

  11. Pacific Northwest Laboratory: Director`s overview of research performed for DOE Office of Health And Environmental Research

    SciTech Connect (OSTI)

    NONE

    1995-06-01T23:59:59.000Z

    A significant portion of the research undertaken at Pacific Northwest Laboratory (PNL) is focused on the strategic programs of the US Department of Energy`s (DOE) Office of Health and Environmental Research (OHER). These programs, which include Environmental Processes (Subsurface Science, Ecosystem Function and Response, and Atmospheric Chemistry), Global Change (Climate Change, Environmental Vulnerability, and Integrated Assessments), Biotechnology (Human Genome and Structural Biology), and Health (Health Effects and Medical Applications), have been established by OHER to support DOE business areas in science and technology and environmental quality. PNL uses a set of critical capabilities based on the Laboratory`s research facilities and the scientific and technological expertise of its staff to help OHER achieve its programmatic research goals. Integration of these capabilities across the Laboratory enables PNL to assemble multidisciplinary research teams that are highly effective in addressing the complex scientific and technical issues associated with OHER-sponsored research. PNL research efforts increasingly are focused on complex environmental and health problems that require multidisciplinary teams to address the multitude of time and spatial scales found in health and environmental research. PNL is currently engaged in research in the following areas for these OHER Divisions: Environmental Sciences -- atmospheric radiation monitoring, climate modeling, carbon cycle, atmospheric chemistry, ecological research, subsurface sciences, bioremediation, and environmental molecular sciences; Health Effects and Life Sciences -- cell/molecular biology, and biotechnology; Medical Applications and Biophysical Research -- analytical technology, and radiological and chemical physics. PNL`s contributions to OHER strategic research programs are described in this report.

  12. American Journal of Public Health | April 2002, Vol 92, No. 4598 | Public Health Matters | Peer Reviewed | Waitzkin et al. PUBLIC HEALTH MATTERS

    E-Print Network [OSTI]

    Bock, John

    effects on individuals.This reform did not address the problems of the uninsured. (Am J Public Health-subsidize the costs of health care also have contributed to access problems for low-income and uninsured per- sons.8 health centers cut services owing to the effects of Medicaid managed care, the costs of caring

  13. Department of Public Health and Community Medicine University of Verona

    E-Print Network [OSTI]

    Romeo, Alessandro

    Department of Public Health and Community Medicine University of Verona Section of Psychiatry (Head Collaborating Centre for Research and Training in Mental Health and Service Evaluation (Director: Professor of mental health, costs evaluation, evaluation of mental health services, effectiveness of psychosocial

  14. Study of air pollution: Effects of ozone on neuropeptide-mediated responses in human subjects. Final report

    SciTech Connect (OSTI)

    Boushey, H.A.

    1991-11-01T23:59:59.000Z

    The study examined the hypothesis that ozone inactivates the enzyme, neutral endopeptidase, responsible for limiting the effects of neuropeptides released from afferent nerve endings. Cough response of capsaicin solution delivered from a nebulizer at 2 min. intervals until two or more coughs were produced. Other endpoints measured included irritative symptoms as rated by the subjects on a nonparametric scale, spirometry, of each concentration of ozone were compared to those of filtered air in a single-blind randomized sequence. The results indicate that a 2 h. exposure to 0.4 ppm of ozone with intermittent light exercise alters the sensitivity of airway nerves that mediate the cough response to inhaled materials. This dose of ozone also caused a change in FEV1. A lower level of ozone, 0.02 ppm, caused a change in neither cough threshold nor FEV1, even when the duration of exposure was extended to three hours. The findings are consistent with the author's hypothesis that ozone may sensitize nerve endings in the airways by inactivating neutral endopeptidase, an enzyme that regulates their activity, but they do not demonstrate that directly examining an effect directly mediated by airway nerves allows detection of effects of ozone at doses below those causing effects detected by standard tests of pulmonary function.

  15. Effects of PGF{sub 2{alpha}} on human melanocytes and regulation of the FP receptor by ultraviolet radiation

    SciTech Connect (OSTI)

    Scott, Glynis [Department of Dermatology, University of Rochester School of Medicine, Box 697, 601 Elmwood Avenue, Rochester, NY 14642 (United States)]. E-mail: Glynis_Scott@urmc.rochester.edu; Jacobs, Stacey [Department of Dermatology, University of Rochester School of Medicine, Box 697, 601 Elmwood Avenue, Rochester, NY 14642 (United States); Leopardi, Sonya [Department of Dermatology, University of Rochester School of Medicine, Box 697, 601 Elmwood Avenue, Rochester, NY 14642 (United States); Anthony, Frank A. [Schering-Plough HealthCare Products Inc., Memphis TN (United States); Learn, Doug [Charles River DDS, Argus Division, Horsham, PA (United States); Malaviya, Rama [University of Medicine and Dentistry, RWJMS, New Brunswick, NJ (United States); Pentland, Alice [Department of Dermatology, University of Rochester School of Medicine, Box 697, 601 Elmwood Avenue, Rochester, NY 14642 (United States)

    2005-04-01T23:59:59.000Z

    Prostaglandins are potent lipid hormones that activate multiple signaling pathways resulting in regulation of cellular growth, differentiation, and apoptosis. In the skin, prostaglandins are rapidly released by keratinocytes following ultraviolet radiation and are chronically present in inflammatory skin lesions. We have shown previously that melanocytes, which provide photoprotection to keratinocytes through the production of melanin, express several receptors for prostaglandins, including the PGE{sub 2} receptors EP{sub 1} and EP{sub 3} and the PGF{sub 2{alpha}} receptor FP, and that PGF{sub 2{alpha}} stimulates melanocyte dendricity. We now show that PGF{sub 2{alpha}} stimulates the activity and expression of tyrosinase, the rate-limiting enzyme in melanin synthesis. Analysis of FP receptor regulation showed that the FP receptor is regulated by ultraviolet radiation in melanocytes in vitro and in human skin in vivo. We also show that ultraviolet irradiation stimulates production of PGF{sub 2{alpha}} by melanocytes. These results show that PGF{sub 2{alpha}} binding to the FP receptor activates signals that stimulate a differentiated phenotype (dendricity and pigmentation) in melanocytes. The regulation of the FP receptor and the stimulation of production of PGF{sub 2{alpha}} in melanocytes in response to ultraviolet radiation suggest that PGF{sub 2{alpha}} could act as an autocrine factor for melanocyte differentiation.

  16. SR-2508 plus buthionine sulfoximine or SR-2508 alone: effects on the radiation response and the glutathione content of a human tumor xenograft

    SciTech Connect (OSTI)

    Lespinasse, F.; Biscay, P.; Malaise, E.P.; Guichard, M.

    1987-04-01T23:59:59.000Z

    This study determined the radiosensitivity of the human tumor xenograft HT29 and its glutathione (GSH) and cysteine (CYS) contents after treatment with both buthionine sulfoximine (BSO) and SR-2508 or SR-2508 alone. Tumor radiosensitivity was assessed by the in vitro colony assay and thiol content was measured by high-performance liquid chromatography. The radiosensitizing effect of SR-2508 is dose dependent and increases when higher doses of radiation are given. SR-2508 given alone does not modify GSH and CYS content; however, when given with BSO, the GSH level is significantly reduced, yet radiosensitivity of the HT29 tumor is only slightly increased. These results have been compared to our previously observed results of HT29 treatment with misonidazole (MISO), BSO, or MISO + BSO.

  17. Improving human effectiveness for extreme-scale problem solving : final report (assessing the effectiveness of electronic brainstorming in an industrial setting).

    SciTech Connect (OSTI)

    Dornburg, Courtney C.; Stevens, Susan Marie; Bauer, Travis L.; Davidson, George S.; Forsythe, James Chris; Hendrickson, Stacey M. Langfitt

    2007-09-01T23:59:59.000Z

    An experiment was conducted comparing the effectiveness of individual versus group electronic brainstorming in order to address difficult, real world challenges. While industrial reliance on electronic communications has become ubiquitous, empirical and theoretical understanding of the bounds of its effectiveness have been limited. Previous research using short-term, laboratory experiments have engaged small groups of students in answering questions irrelevant to an industrial setting. The current experiment extends current findings beyond the laboratory to larger groups of real-world employees addressing organization-relevant challenges over the course of four days. Findings are twofold. First, the data demonstrate that (for this design) individuals perform at least as well as groups in producing quantity of electronic ideas, regardless of brainstorming duration. However, when judged with respect to quality along three dimensions (originality, feasibility, and effectiveness), the individuals significantly (p<0.05) out performed the group working together. The theoretical and applied (e.g., cost effectiveness) implications of this finding are discussed. Second, the current experiment yielded several viable solutions to the wickedly difficult problem that was posed.

  18. TOXNET and Beyond-Using the National Library of Medicine's Environmental Health and Toxicology Portal

    SciTech Connect (OSTI)

    Templin-Branner, Wilma

    2011-01-01T23:59:59.000Z

    The purpose of this training is to familiarize participants with reliable online environmental health and toxicology information, from the National Library of Medicine and other reliable sources. Skills and knowledge acquired in this training class will enable participants to access, utilize, and refer others to environmental health and toxicology information. After completing this course, participants will be able to: (1) Identify quality, accurate, and authoritative online resources pertaining to environmental health, toxicology, and related medical information; (2) Demonstrate the ability to perform strategic search techniques to find relevant online information; and (3) Apply the skills and knowledge obtained in this class to their organization's health information needs. NLMs TOXNET (Toxicology Data Network) is a free, Web-based system of databases on toxicology, environmental health, hazardous chemicals, toxic releases, chemical nomenclatures, and specialty areas such as occupational health and consumer products. Types of information in the TOXNET databases include: (1) Specific chemicals, mixtures, and products; (2) Unknown chemicals; and (3) Special toxic effects of chemicals in humans and/or animals.

  19. Master of Science in Health Outcomes and Policy For more information, call the Department of Health Outcomes and Policy at 352-265-2505,

    E-Print Network [OSTI]

    Slatton, Clint

    , health outcomes for a range of medical conditions, and clinical effectiveness research. Clinicians who research and implementation science. Prepare to conduct health outcomes assessments and clinical Science ·Measuring and Analyzing Health Outcomes ·Applied Biostatistics I ·Introduction to Clinical

  20. Characterization of the effects of x-ray irradiation on the hierarchical structure and mechanical properties of human cortical bone

    SciTech Connect (OSTI)

    Barth, Holly; Zimmermann, Elizabeth; Schaible, Eric; Tang, Simon; Alliston, Tamara; Ritchie, Robert

    2011-08-19T23:59:59.000Z

    Bone comprises a complex structure of primarily collagen, hydroxyapatite and water, where each hierarchical structural level contributes to its strength, ductility and toughness. These properties, however, are degraded by irradiation, arising from medical therapy or bone-allograft sterilization. We provide here a mechanistic framework for how irradiation affects the nature and properties of human cortical bone over a range of characteristic (nano to macro) length-scales, following x-­ray exposures up to 630 kGy. Macroscopically, bone strength, ductility and fracture resistance are seen to be progressively degraded with increasing irradiation levels. At the micron-­scale, fracture properties, evaluated using in-situ scanning electron microscopy and synchrotron x-ray computed micro-tomography, provide mechanistic information on how cracks interact with the bone-matrix structure. At sub-micron scales, strength properties are evaluated with in-situ tensile tests in the synchrotron using small-/wide-angle x-ray scattering/diffraction, where strains are simultaneously measured in the macroscopic tissue, collagen fibrils and mineral. Compared to healthy bone, results show that the fibrillar strain is decreased by ~40% following 70 kGy exposures, consistent with significant stiffening and degradation of the collagen. We attribute the irradiation-­induced deterioration in mechanical properties to mechanisms at multiple length-scales, including changes in crack paths at micron-­scales, loss of plasticity from suppressed fibrillar sliding at sub-­micron scales, and the loss and damage of collagen at the nano-­scales, the latter being assessed using Raman and Fourier-Transform-Infrared spectroscopy and a fluorometric assay.

  1. Effect of iodination on human growth hormone and prolactin: characterized by bioassay, radioimmunoassay, radioreceptor assay, and electrophoresis

    SciTech Connect (OSTI)

    Hughes, J.P.; Tanaka, T.; Gout, P.W.; Beer, C.T.; Noble, R.L.; Friesen, H.G.

    1982-09-01T23:59:59.000Z

    Human GH (hGH) and PRL (hPRL) were iodinated using lactoperoxidase. The iodinated hormones were characterized by RIA, radioreceptor assay (RRA), and bioassay (BA) using the Nb2 Node lymphoma cell line. The proportion of tracer that could bind to rat liver membranes or rabbit antibodies was determined, and the distribution of iodinated hormones was examined using polyacrylamide gel electrophoresis. Excess antibody was capable of precipitating 87.9% of the radioactivity associated with the hGH tracer and 86.0% of the hPRL tracer. The maximal specific binding to a liver membrane preparation averaged 67.3% of the (/sup 125/I)iodo-hGH radioactivity and 48.8% of the (/sup 125/I)iodo-hPRL radioactivity. The respective BA and RRA activity estimates for (/sup 125/I)iodo-hGH averaged 90% and 114% of the activity measured by the RIA. For (/sup 125/I)iodo-hPRL, the values were 75% by BA and 68% by RRA. The bioactivity profiles of iodinated hGH and hPRL shifted anodally on polyacrylamide gel electrophoresis in comparison to the bioactivity distribution of the respective uniodinated hormones. Iodine incorporation rather than oxidation appeared to be responsible for the shift. After electrophoresis, all eluates which contained significant radioactivity were active in the BA and RIA. Furthermore, specific activities calculated from the bioactive hormone and radioactivity in each electrophoretic segment agreed well with the average specific activity estimated from the amount of iodine incorporated into the protein peak upon gel filtration. These data suggest that hGH and hPRL to a major degree retain biological integrity after iodination.

  2. Effect of iodination on human growth hormone and prolactin: characterized by bioassay, radioimmunoassay, radioreceptor assay, and electrophoresis

    SciTech Connect (OSTI)

    Hughes, J.P. (Univ. of Manitoba, Winnipeg, Canada); Tanaka, T.; Gout, P.W.; Beer, C.T.; Noble, R.L.; Friesen, H.G.

    1982-09-01T23:59:59.000Z

    Human GH (hGH) and PRL (hPRL) were iodinated using lactoperoxidase. The iodinated hormones were characterized by RIA, radioreceptor assay (RRA), and bioassay (BA) using the Nb2 Node lymphoma cell line. The proportion of tracer that could bind to rat liver membranes or rabbit antibodies was determined, and the distribution of iodinated hormones was examined using polyacrylamide gel electrophoresis. Excess antibody was capable of precipitating 87.9% of the radioactivity associated with the hGH tracer and 86.0% of the hPRL tracer. The maximal specific binding to a liver membrane preparation averaged 67.3% of the (/sup 125/I)iodo-hGH radioactivity and 48.8% of the (/sup 125/I)iodo-hPRL radioactivity. The respective BA and RRA activity estimates for (/sup 125/)iodo-hGH averaged 90% and 114% of the activity measured by the RIA. For (/sup 125/I)iodo-hPRL, the values were 75% by BA and 68% by RRA. The bioactivity profiles of iodinated hGH and hPRL shifted anodally on polyacrylamide gel electrophoresis in comparison to the bioactivity distribution of the respective uniodinated hormones. Iodine incorporation rather than oxidation appeared to be responsible for the shift. After electrophoresis, all eluates which contained significant radioactivity were active in the BA and RIA. Furthermore, specific activities calculated from the bioactive hormone and radioactivity in each electrophoretic segment agreed well with the average specific activity estimated from the amount of iodine incorporated into the protein peak upon gel filtration. These data suggest that hGH and hPRL to a major degree retain biological integrity after iodination.

  3. LDRD final report for improving human effectiveness for extreme-scale problem solving : assessing the effectiveness of electronic brainstorming in an industrial setting.

    SciTech Connect (OSTI)

    Dornburg, Courtney C.; Stevens, Susan Marie; Davidson, George S.; Hendrickson, Stacey M. Langfitt

    2008-09-01T23:59:59.000Z

    An experiment was conducted comparing the effectiveness of individual versus group electronic brainstorming in order to address difficult, real world challenges. While industrial reliance on electronic communications has become ubiquitous, empirical and theoretical understanding of the bounds of its effectiveness have been limited. Previous research using short-term, laboratory experiments have engaged small groups of students in answering questions irrelevant to an industrial setting. The present experiment extends current findings beyond the laboratory to larger groups of real-world employees addressing organization-relevant challenges over the course of four days. Employees and contractors at a national security laboratory participated, either in a group setting or individually, in an electronic brainstorm to pose solutions to a 'wickedly' difficult problem. The data demonstrate that (for this design) individuals perform at least as well as groups in producing quantity of electronic ideas, regardless of brainstorming duration. However, when judged with respect to quality along three dimensions (originality, feasibility, and effectiveness), the individuals significantly (p<0.05) out-performed the group working together. When idea quality is used as the benchmark of success, these data indicate that work-relevant challenges are better solved by aggregating electronic individual responses, rather than electronically convening a group. This research suggests that industrial reliance upon electronic problem solving groups should be tempered, and large nominal groups might be the more appropriate vehicle for solving wicked corporate issues.

  4. A comparison between integrated risk assessment and classical health/environmental assessment: Emerging beneficial properties

    SciTech Connect (OSTI)

    Sekizawa, Jun [Faculty of Integrated Arts and Sciences, University of Tokushima, Japan, 1-1 Minamijosanjimacho, Tokushima 770-8502 (Japan)]. E-mail: sekizawa@ias.tokushima-u.ac.jp; Tanabe, Shinsuke [Center for Marine Environmental Studies, Ehime University, 2-5 Bunkyocho, Matsuyama, Ehime 790-8577 (Japan)

    2005-09-01T23:59:59.000Z

    Both humans and wildlife are exposed to various types of halogenated organic compounds such as polychlorinated biphenyls (PCBs) and dichlorodiphenyltrichloroethane (DDT), typically old chemicals, and tris(4-chlorophenyl) methane (TCPM) and brominated flame retardants, some new chemicals, simultaneously. Classical risk assessment has evaluated health and ecological risks independently by experts from different disciplines. Taking into considerations the recent concerns about endocrine disrupting chemicals and the progress of research in related areas, we integrated and assessed data on exposure and potential effects in humans and wildlife. Comparisons were made for organ concentrations, body burdens of several organochlorine compounds (OCs), metabolic capacities between humans and various wildlife. When we integrate the knowledge on effects and exposure in humans and in wildlife, new insights were suggested about similarities and/or differences in potential effects among various human populations living on different foods and having different body burdens. Combining existing information with emerging knowledge of mechanisms of actions on endocrine disrupting chemicals after exposure to above chemicals during early developmental stages will further elucidate potential risks from exposure to those chemicals.

  5. Partial hypoxia as a cause of radioresistance in a human tumor xenograft: its influence illustrated by the sensitizing effect of misonidazole and hyperbaric oxygen

    SciTech Connect (OSTI)

    Reynaud-Bougnoux, A.; Lespinasse, F.; Malaise, E.P.; Guichard, M.

    1986-08-01T23:59:59.000Z

    While previous studies with three human tumor xenografts suggest that contact-resistance plays a major role in the response of these tumors to radiation, it remains possible that partial hypoxia may provide an alternate explanation. The present study was carried out to check this possibility by investigating the influence of misonidazole (MISO) and hyperbaric oxygen (HBO) on both the initial and distal components of the survival curves of HRT18 tumor cells. The effect of a challenge dose of radiation on the initial radioresistance of this tumor was also studied. To assess the effects of MISO and HBO, tumor cell survival was determined by excision assay in two groups of tumor-bearing mice, one given MISO (1 mg/g body weight, i.p.) 45 min before irradiation and the other exposed to HBO (3.5 bars). MISO treatment caused greater sensitization than HBO. The enhancement ratios at the 5.10(-1) level were 1.7 (MISO) and 1.7 (HBO); at the 10(-1) level, they were 1.6 (MISO) and 1.4 (HBO); while at 10(-2), they were 1.6 (MISO) and 1.4 (HBO). These two sensitizing effects favor the hypothesis that solid tumors contain a compartment of partially hypoxic cells. To study the effect of a challenge radiation dose on initial radioresistance, tumors were given a challenge dose of 8 Gy, followed 24-48 hr later by doses ranging from 2-12 Gy. The challenge dose did not modify the shape of the survival curve.

  6. The accumulations of HIF-1? and HIF-2? by JNK and ERK are involved in biphasic effects induced by different levels of arsenite in human bronchial epithelial cells

    SciTech Connect (OSTI)

    Xu, Yuan; Li, Yuan [Institute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing 210029, Jiangsu (China) [Institute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing 210029, Jiangsu (China); The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 210029, Jiangsu (China); Li, Huiqiao [Qujing Center for Disease Control and Prevention, Qujing 655000, Yunnan (China)] [Qujing Center for Disease Control and Prevention, Qujing 655000, Yunnan (China); Pang, Ying; Zhao, Yue; Jiang, Rongrong; Shen, Lu [Institute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing 210029, Jiangsu (China) [Institute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing 210029, Jiangsu (China); The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 210029, Jiangsu (China); Zhou, Jianwei; Wang, Xinru [The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 210029, Jiangsu (China)] [The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 210029, Jiangsu (China); Liu, Qizhan, E-mail: drqzliu@hotmail.com [Institute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing 210029, Jiangsu (China) [Institute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing 210029, Jiangsu (China); The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 210029, Jiangsu (China)

    2013-01-15T23:59:59.000Z

    The biphasic effects of arsenite, in which low levels of arsenite induce cell proliferation and high levels of arsenite induce DNA damage and apoptosis, apparently contribute to arsenite-induced carcinogenesis. However, the mechanisms underlying this phenomenon are not well understood. In this study, we investigated the effects of different levels of arsenite on cell proliferation, DNA damage and apoptosis as well as on signal transduction pathways in human bronchial epithelial (HBE) cells. Our results show that a low level of arsenite activates extracellular signal-regulated kinases (ERK), which probably mediate arsenite-inhibited degradation of ubiquitinated hypoxia-inducible factor-2? (HIF-2?) in HBE cells. ERK inhibition blocks cell proliferation induced by a low level of arsenite, in part via HIF-2?. In contrast, a high level of arsenite activates c-Jun N-terminal kinases (JNK), which provoke a response to suppress ubiquitinated HIF-1? degradation. Down-regulation of HIF-1? by inhibiting JNK, however, increases the DNA damage but decreases the apoptosis induced by a high level of arsenite. Thus, data in the present study suggest that the accumulations of HIF-1? and HIF-2? by JNK and ERK are involved in different levels of arsenite-induced biphasic effects, with low levels of arsenite inducing cell proliferation and high levels of arsenite inducing DNA damage and apoptosis in HBE cells. -- Highlights: ? Biphasic effects induced by different concentrations of arsenite. ? Different regulation of ERK or JNK signal pathway by arsenite. ? Different regulation of HIF1? or HIF 2? by arsenite.

  7. E-Print Network 3.0 - address public health Sample Search Results

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Environmental Sciences and Ecology 66 Assuring Equity Through Health and Health Care Reform Conference Registration Information (Type or Print) Summary: Effectiveness...

  8. Introduction Health Sciences

    E-Print Network [OSTI]

    Banbara, Mutsunori

    with the originality and creativity to establish total health care, (2advanced healthcare specialists with abundant and researchers who can put total health care into practice. 21 20084 2 3 total health care #1232 Introduction Guide Entrance Life Career Inquiries Health Sciences Health Problems

  9. winter 2015 Health Informatics

    E-Print Network [OSTI]

    California at Davis, University of

    UinG anD PrOfeSSiOnal eDUCatiOn HEALTH INFORMATICS ANd ANALYTICS #12;2 Advancing Health Care Through.S. health care prior to commencing study. High-quality, Convenient Online Learning Format All courses, computer science and health care. In this introductory course, gain broad exposure to the field of health

  10. Assessing the health risks of natural CO2 seeps in Italy

    SciTech Connect (OSTI)

    Roberts, J.J.; Wood, R.A.; Haszeldine, R.S. [Scottish Carbon Capture and Storage, School of GeoSciences, Grant Institute, University of Edinburgh, West Mains Road, Edinburgh EH9 3JW, Scotland (United Kingdom)

    2011-10-04T23:59:59.000Z

    Industrialized societies which continue to use fossil fuel energy sources are considering adoption of Carbon Capture and Storage (CCS) technology to meet carbon emission reduction targets. Deep geological storage of CO2 onshore faces opposition regarding potential health effects of CO2 leakage from storage sites. There is no experience of commercial scale CCS with which to verify predicted risks of engineered storage failure. Studying risk from natural CO2 seeps can guide assessment of potential health risks from leaking onshore CO2 stores. Italy and Sicily are regions of intense natural CO2 degassing from surface seeps. These seeps exhibit a variety of expressions, characteristics (e.g., temperature/ flux), and location environments. Here we quantify historical fatalities from CO2 poisoning using a database of 286 natural CO2 seeps in Italy and Sicily. We find that risk of human death is strongly influenced by seep surface expression, local conditions (e.g., topography and wind speed), CO2 flux, and human behavior. Risk of accidental human death from these CO2 seeps is calculated to be 10-8 year-1 to the exposed population. This value is significantly lower than that of many socially accepted risks. Seepage from future storage sites is modeled to be less than Italian natural flux rates. With appropriate hazard management, health risks from unplanned seepage at onshore storage sites can be adequately minimized.

  11. Independent Effects of Song Quality and Experience with Photostimulation on Expression of the

    E-Print Network [OSTI]

    Sockman, Keith W.

    and attributed the proximate control of these effects Correspondence to: K.W. Sockman (kws@unc.edu). Contract Institute of Neurological Disorders and Stroke); contract grant numbers: F32 41854 to K.W.S. and R01 35467 grant sponsors: NICHD (National Institute of Child Health and Human Development) and NINDS (National

  12. Environmental Health Perspectives VOLUME 109 | NUMBER 5 | May 2001 481 Quantifying the Effects of Exposure to Indoor Air Pollution from Biomass

    E-Print Network [OSTI]

    Kammen, Daniel M.

    of Exposure to Indoor Air Pollution from Biomass Combustion on Acute Respiratory Infections in Developing to indoor air pollution, especially to particulate matter, from the combustion of biofuels (wood, charcoal to indoor air pollution high on the agenda of international development and public health organizations (10

  13. Selection of a discount rate for use in NRC regulatory analyses and application of discount rates to future averted health effects

    SciTech Connect (OSTI)

    Paananen, O.H.; Hendrickson, P.L.

    1993-01-01T23:59:59.000Z

    The principal objective of this report is to provide background information and recommendations on the use of discount rates in the regulatory analysis process. The report focuses on two issues selecting the appropriate discount rate or rates to use when conducting a regulatory analysis, and applying the selected discount rate to future health-related benefits estimated to result from alternative regulatory actions.

  14. Effects of Heat Stress and Increased Protein Fed in Milk Replacers on the Health and Growth Parameters of Neonatal Holstein Bull Calves 

    E-Print Network [OSTI]

    Krenek, Andrew

    2012-10-19T23:59:59.000Z

    Objectives of the study were to evaluate if calves fed 6 L of high protein milk replacer (HPMR; 1135 g/d, 28% crude protein (CP), 20% fat) had improved performance and health as compared to calves fed 4 L of a conventional milk replacer (CMR; 454 g...

  15. EXHALE Exploration of Health and Lungs in the Environment Exposure to poor air quality is recognised to have a detrimental effect on children's

    E-Print Network [OSTI]

    Applebaum, David

    EXHALE ­ Exploration of Health and Lungs in the Environment Exposure to poor air quality, the air pollutants which damage lungs and are linked to respiratory problems such as asthma. A Low these standards pay a charge or fine. The EXHALE study is examining if traffic emissions inhibit lung growth

  16. Sandia Energy - Structural Health Monitoring

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Structural Health Monitoring Home Stationary Power Energy Conversion Efficiency Wind Energy Materials, Reliability, & Standards Structural Health Monitoring Structural Health...

  17. Regulation of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase expression and activity in the hypophysectomized rat ovary: Interactions between the stimulatory effect of human chorionic gonadotropin and the luteolytic effect of prolactin

    SciTech Connect (OSTI)

    Martel, C.; Labrie, C.; Dupont, E.; Couet, J.; Trudel, C.; Rheaume, E.; Simard, J.; Luu-The, V.; Pelletier, G.; Labrie, F. (CHUL Research Center, Quebec (Canada))

    1990-12-01T23:59:59.000Z

    The enzyme 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase (3 beta-HSD) catalyzes an obligatory step in the conversion of pregnenolone and other 5-ene-3 beta-hydroxysteroids into progesterone as well as precursors of all androgens and estrogens in the ovary. Since 3 beta-HSD is likely to be an important target for regulation by pituitary hormones, we have studied the effect of chronic treatment with LH (hCG), FSH, and PRL on ovarian 3 beta-HSD expression and activity in hypophysectomized adult female rats. Human CG (hCG) (10 IU, twice a day (bid)), ovine FSH (0.5 microgram, bid), and ovine PRL (1 mg, bid) were administered, singly or in combination, for a period of 10 days starting 15 days after hypophysectomy. In hypophysectomized rats, PRL exerted a potent inhibitory effect on all the parameters studied. In fact, PRL caused a 81% decrease in ovarian 3 beta-HSD mRNA content accompanied by a similar decrease in 3 beta-HSD activity and protein levels. In addition, ovarian weight decreased by 40% whereas serum progesterone fell dramatically from 1.92 nmol/liter to undetectable levels after treatment with PRL. Whereas hCG alone had only slight stimulatory effects on 3 beta-HSD mRNA, protein content and activity levels, treatment with the gonadotropin partially or completely reversed the potent inhibitory effects of oPRL on all the parameters measured. FSH, on the other hand, had no significant effect on 3 beta-HSD expression and activity. In situ hybridization experiments using the 35S-labeled rat ovary 3 beta-HSD cDNA probe show that the inhibitory effect of PRL is exerted primarily on luteal cell 3 beta-HSD expression and activity. On the other hand, it can be seen that hCG stimulates 3 beta-HSD mRNA accumulation in interstitial cells.

  18. Operational health physics training

    SciTech Connect (OSTI)

    NONE

    1992-06-01T23:59:59.000Z

    The initial four sections treat basic information concerning atomic structure and other useful physical quantities, natural radioactivity, the properties of {alpha}, {beta}, {gamma}, x rays and neutrons, and the concepts and units of radiation dosimetry (including SI units). Section 5 deals with biological effects and the risks associated with radiation exposure. Background radiation and man-made sources are discussed next. The basic recommendations of the ICRP concerning dose limitations: justification, optimization (ALARA concepts and applications) and dose limits are covered in Section seven. Section eight is an expanded version of shielding, and the internal dosimetry discussion has been extensively revised to reflect the concepts contained in the MIRD methodology and ICRP 30. The remaining sections discuss the operational health physics approach to monitoring radiation. Individual sections include radiation detection principles, instrument operation and counting statistics, health physics instruments and personnel monitoring devices. The last five sections deal with the nature of, operation principles of, health physics aspects of, and monitoring approaches to air sampling, reactors, nuclear safety, gloveboxes and hot cells, accelerators and x ray sources. Decontamination, waste disposal and transportation of radionuclides are added topics. Several appendices containing constants, symbols, selected mathematical topics, and the Chart of the Nuclides, and an index have been included.

  19. Medicine and public health in a multiethnic world 

    E-Print Network [OSTI]

    Bhopal, Raj

    2009-01-01T23:59:59.000Z

    Achievement of medical and public health goals requires mutual understanding between professionals and the public, a challenge in diverse societies. Despite their massive diversity humans belong to one species, with race ...

  20. Addressing Genetics Delivering Health

    E-Print Network [OSTI]

    Rambaut, Andrew

    Addressing Genetics Delivering Health A strategy for advancing the dissemination and application of genetics knowledge throughout our health professions Funded by Hilary Burton September 2003 Executive education of health workers q providing strategic overview of education programme q collaborating

  1. DIRECTORY OF HEALTH SERVICES

    E-Print Network [OSTI]

    Yates, Andrew

    a centralized resource of regional health care services for persons with developmental disabilitiesDIRECTORY OF HEALTH SERVICES FOR BRONX RESIDENTS WITH DEVELOPMENTAL DISABILITIES 2012 Compiled Albert Einstein College of Medicine in collaboration with Health Services Committee, Bronx Developmental

  2. Developing Human Performance Measures

    SciTech Connect (OSTI)

    Jeffrey Joe; Bruce Hallbert; Larry Blackwood; Donald Dudehoeffer; Kent Hansen

    2006-05-01T23:59:59.000Z

    Through the reactor oversight process (ROP), the U.S. Nuclear Regulatory Commission (NRC) monitors the performance of utilities licensed to operate nuclear power plants. The process is designed to assure public health and safety by providing reasonable assurance that licensees are meeting the cornerstones of safety and designated crosscutting elements. The reactor inspection program, together with performance indicators (PIs), and enforcement activities form the basis for the NRC’s risk-informed, performance based regulatory framework. While human performance is a key component in the safe operation of nuclear power plants and is a designated cross-cutting element of the ROP, there is currently no direct inspection or performance indicator for assessing human performance. Rather, when human performance is identified as a substantive cross cutting element in any 1 of 3 categories (resources, organizational or personnel), it is then evaluated for common themes to determine if follow-up actions are warranted. However, variability in human performance occurs from day to day, across activities that vary in complexity, and workgroups, contributing to the uncertainty in the outcomes of performance. While some variability in human performance may be random, much of the variability may be attributed to factors that are not currently assessed. There is a need to identify and assess aspects of human performance that relate to plant safety and to develop measures that can be used to successfully assure licensee performance and indicate when additional investigation may be required. This paper presents research that establishes a technical basis for developing human performance measures. In particular, we discuss: 1) how historical data already gives some indication of connection between human performance and overall plant performance, 2) how industry led efforts to measure and model human performance and organizational factors could serve as a data source and basis for a framework, 3) how our use of modeling and simulation techniques could be used to develop and validate measures of human performance, and 4) what the possible outcomes are from this research as the modeling and simulation efforts generate results.

  3. University Health Care Health Sciences Center

    E-Print Network [OSTI]

    Feschotte, Cedric

    University Health Care Health Sciences Center 30 N. 1900 E. 6DOW /DNH &LW\\ 87 84132-2204 Phone and your child. University Health Care School of Medicine Division of Pediatric Nephrology & Hypertension care physician after each visit. x If you would like a copy of your child's clinic note you must

  4. Health and Counselling Services SFU Health Promotion

    E-Print Network [OSTI]

    Health and Counselling Services SFU Health Promotion A division of Student Services HEALTHY CAMPUS COMMUNITY 2 0 1 3 R E P O R T #12;Dr. Tim Rahilly Dr. Nancy Johnston FOREWORD The health and well. We have a responsibility as a caring community to create a setting that not only supports students

  5. Scottish Air Pollution and Health Workshop

    E-Print Network [OSTI]

    Scottish Air Pollution and Health Workshop Session 4 Joint Research Policy Needs and Interactions needs and how can we work together effectively on these to reduce the adverse effects of air pollution together effectively on these to reduce the adverse effects of air pollution in Scotland. Modelling

  6. ORISE: Health Physics Training

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Health Physics Training Student performs an analysis during an ORAU health physics training course Training and educating a highly skilled workforce that can meet operational...

  7. ORISE: Public Health Communication

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Communication Public Health Communication The Oak Ridge Institute for Science and Education (ORISE) assists government agencies and organizations in addressing public health...

  8. ORISE: Public Health Preparedness

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    by convening community-based workshops and key stakeholder meetings aimed at managing a health care surge during a public health emergency. By identifying and involving key...

  9. Finite Element Simulation of Piezoelectric Wafer Active Sensors for Structural Health Monitoring with Coupled-Filed

    E-Print Network [OSTI]

    Giurgiutiu, Victor

    Finite Element Simulation of Piezoelectric Wafer Active Sensors for Structural Health Monitoring) is emerging as an effective and powerful technique in structural health monitoring (SHM). Modeling to analytical calculation and experimental data. Key words: Structural Health Monitoring, PWAS, finite element

  10. Suffolk County Department of Health Services

    E-Print Network [OSTI]

    . heavy metal sludges, mixtures and solutions in excess of the allowable concentrations listed in Title 6 ground or finished floor elevation. #12;Page #2 2.2 Commissioner - Commissioner of Suffolk County present, an actual or potential hazard to human health, or to the drinking water supply, if such substance

  11. Does Health Insurance and Seeing the Doctor Keep You Out of the Hospital? We obtain estimates of associations between health insurance and hospitalization and between

    E-Print Network [OSTI]

    Mateo, Jill M.

    health care reform debate, as illustrated by the quote from Kathleen Sebelius, Secretary of the U at a presentation of this research at the American Enterprise Institute for their comments. #12;1 "Our health care.S. Department of Health and Human Services. Indeed, primary care is central focus of the Patient Protection

  12. Superfund Cleanups and Infant Health

    E-Print Network [OSTI]

    Currie, Janet

    We are the first to examine the effect of Superfund cleanups on infant health rather than focusing on proximity to a site. We study singleton births to mothers residing within 5km of a Superfund site between 1989-2003 in ...

  13. Boise State University College of Health Sciences

    E-Print Network [OSTI]

    Barrash, Warren

    . Scope: In order to comply with health care industry partners' and/or clinical agencies' requirementsBoise State University CHS-314.0 College of Health Sciences Effective Date: 09-27-13 Revised Date for admission into and progression through programs that include the direct delivery of patient care services

  14. Assessing corporate project impacts in changeable contexts: A human rights perspective

    SciTech Connect (OSTI)

    Salcito, Kendyl, E-mail: kendyl.salcito@unibas.ch [Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, P.O. Box, CH-4002 Basel (Switzerland); University of Basel, P.O. Box, CH-4003 Basel (Switzerland); NomoGaia, 1900 Wazee Street, Suite 303, Denver, CO 80202 (United States); NewFields, LLC, Denver, CO 80202 (United States); Singer, Burton H., E-mail: bhsinger@epi.ufl.edu [Emerging Pathogens Institute, University of Florida, Gainesville, FL 32610 (United States); Krieger, Gary R., E-mail: gkrieger@newfields.com [NewFields, LLC, Denver, CO 80202 (United States); Weiss, Mitchell G., E-mail: mitchell-g.weiss@unibas.ch [Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, P.O. Box, CH-4002 Basel (Switzerland); University of Basel, P.O. Box, CH-4003 Basel (Switzerland); Wielga, Mark, E-mail: wielga@nomogaia.org [NomoGaia, 1900 Wazee Street, Suite 303, Denver, CO 80202 (United States); NewFields, LLC, Denver, CO 80202 (United States); Utzinger, Jürg, E-mail: juerg.utzinger@unibas.ch [Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, P.O. Box, CH-4002 Basel (Switzerland); University of Basel, P.O. Box, CH-4003 Basel (Switzerland)

    2014-07-01T23:59:59.000Z

    Project-level impact assessment was originally conceived as a snapshot taken in advance of project implementation, contrasting current conditions with a likely future scenario involving a variety of predicted impacts. Current best practice guidance has encouraged a shift towards longitudinal assessments from the pre-project stage through the implementation and operating phases. Experience and study show, however, that assessment of infrastructure-intensive projects rarely endures past the project's construction phase. Negative consequences for environmental, social and health outcomes have been documented. Such consequences clarify the pressing need for longitudinal assessment in each of these domains, with human rights impact assessment (HRIA) as an umbrella over, and critical augmentation of, environmental, social and health assessments. Project impacts on human rights are more closely linked to political, economic and other factors beyond immediate effects of a company's policy and action throughout the project lifecycle. Delineating these processes requires an adequate framework, with strategies for collecting longitudinal data, protocols that provide core information for impact assessment and guidance for adaptive mitigation strategies as project-related effects change over time. This article presents general principles for the design and implementation of sustained, longitudinal HRIA, based on experience assessing and responding to human rights impact in a uranium mining project in Malawi. The case study demonstrates the value of longitudinal assessment both for limiting corporate risk and improving human welfare. - Graphical abstract: Assessing changes in human rights condition as affected by both project and context, over time. - Highlights: • Corporate capital projects affect human rights in myriad ways. • Ongoing, longitudinal impact assessment techniques are needed. • We present an approach for conducting longitudinal human rights impact assessment. • Our methodology allows distinguishing corporate impacts from contextual changes. • Promptly observing context changes and impacts enables companies to react nimbly.

  15. Master's Degree in Agriculture Plant Health Management Option Option Title: Master of Science (MS) in Agriculture: Plant Health

    E-Print Network [OSTI]

    Collins, Gary S.

    Master's Degree in Agriculture ­ Plant Health Management Option Option Title: Master of Science (MS) in Agriculture: Plant Health Management Department(s) or Program(s): Supported of Agricultural, Human, and Natural Resource Sciences (CAHNRS) Contact Name: Dr. Kim Kidwell, Director MS

  16. About the Air Pollution and Respiratory Health Program The Air Pollution and Respiratory Health Program of the National Center for Environmental Health, Centers for

    E-Print Network [OSTI]

    About the Air Pollution and Respiratory Health Program The Air Pollution and Respiratory Health indoor and outdoor air pollution. CDC's asthma program focuses on three main activities: (1) tracking public health agencies. For example, CDC staff are currently studying the effect of outdoor air pollution

  17. CHEIBA TRUST Health Insurance

    E-Print Network [OSTI]

    CHEIBA TRUST Health Insurance Anthem Blue Cross and Blue Shield www.anthem.com BlueAdvantage Point of Service Plan (HMO/POS) Prime Health Plan (PPO) and Custom Plus Health Plan Phone.................................................................................................................1-800-542-9402 Provider Directories Health and Dental www.anthem.com HMO Chiropractic Landmark

  18. IMMUNIZATION HEALTH SERVICES CHECKLIST

    E-Print Network [OSTI]

    Matsuda, Noboru

    (regardless of insurance coverage), as well as current staff and faculty. We offer medical care, health1 HEALTH AND IMMUNIZATION GUIDE #12;2 HEALTH SERVICES CHECKLIST Immunization Form due (one timeEdu and Haven Courses completed by: August 11, 2014 WWW.CMU.EDU/HEALTH-SERVICES Questions? Contact us at 412

  19. IMMUNIZATION HEALTH SERVICES CHECKLIST

    E-Print Network [OSTI]

    Matsuda, Noboru

    . We offer medical care, health promotion and insurance services, including: Alcohol and Drug1 HEALTH AND IMMUNIZATION GUIDE #12;2 HEALTH SERVICES CHECKLIST Immunization Form due (one time ­ September 5, 2014 Spring Semester 2015 ­ January 31, 2015 Summer Semester 2015 ­ June 15, 2015 WWW.CMU.EDU/HEALTH

  20. POSTGRADUATE Health Sciences

    E-Print Network [OSTI]

    O'Mahony, Donal E.

    .Sc.Courses Cancer Care 54 Dementia 55 Gerontological Nursing 56 Mental Health 57 Midwifery 59 Nursing 60 Palliative Care 61 Postgraduate Diplomas Clinical Health Sciences Education 62 Nursing (Specialist) 63 HigherPOSTGRADUATE COURSES 2012 Health Sciences TheUniversityofDublinPostgraduateCourses2012Health

  1. Oregon Health & Science University

    E-Print Network [OSTI]

    Chapman, Michael S.

    to high-quality health care for all, especially Oregonians. 4. Help meet Oregon's health and science, however, has changed dramatically. National and statewide health care reform alters the ways care, including the changing health care environment, new and disruptive technologies, globalization, changing

  2. Graduate Assistant Health Insurance

    E-Print Network [OSTI]

    Johnson, Eric E.

    Center (formerly NMSU Student Health Center) for all outpatient primary health care services. Campus:30 pm by Appt- Psychiatry & Women's Health · 7:30 am- 4:30 pm Urgent Care Evaluation, Pharmacy, Lab, X ­ prescription medications ­ testing & procedures ­ office visits for part-time students #12;United Health Care

  3. Who plans for health improvement? SEA, HIA and the separation of spatial planning and health planning

    SciTech Connect (OSTI)

    Bond, Alan, E-mail: alan.bond@uea.ac.uk [InteREAM (Interdisciplinary Research in Environmental Assessment and Management), School of Environmental Sciences, University of East Anglia, Norwich, NR4 7TJ (United Kingdom)] [InteREAM (Interdisciplinary Research in Environmental Assessment and Management), School of Environmental Sciences, University of East Anglia, Norwich, NR4 7TJ (United Kingdom); Cave, Ben, E-mail: ben.cave@bcahealth.co.uk [Ben Cave Associates Ltd., Leeds (United Kingdom)] [Ben Cave Associates Ltd., Leeds (United Kingdom); Ballantyne, Rob, E-mail: robdballantyne@gmail.com [Planning and Health Consultant, Oxfordshire (United Kingdom)] [Planning and Health Consultant, Oxfordshire (United Kingdom)

    2013-09-15T23:59:59.000Z

    This study examines whether there is active planning for health improvement in the English spatial planning system and how this varies across two regions using a combination of telephone surveys and focus group interviews in 2005 and 2010. The spatial planning profession was found to be ill-equipped to consider the health and well-being implications of its actions, whilst health professionals are rarely engaged and have limited understanding and aspirations when it comes to influencing spatial planning. Strategic Environmental Assessment was not considered to be successful in integrating health into spatial plans, given it was the responsibility of planners lacking the capacity to do so. For their part, health professionals have insufficient knowledge and understanding of planning and how to engage with it to be able to plan for health gains rather than simply respond to health impacts. HIA practice is patchy and generally undertaken by health professionals outside the statutory planning framework. Thus, whilst appropriate assessment tools exist, they currently lack a coherent context within which they can function effectively and the implementation of the Kiev protocol requiring the engagement of health professionals in SEA is not to likely improve the consideration of health in planning while there continues to be separation of functions between professions and lack of understanding of the other profession. -- Highlights: ? Health professionals have limited aspirations for health improvement through the planning system. ? Spatial planners are ill-equipped to understand the health and well-being implications of their activities. ? SEA and HIA currently do not embed health consideration in planning decisions. ? The separation of health and planning functions is problematic for the effective conduct of SEA and/or HIA.

  4. Human-robot cross-training: Computational formulation, modeling and evaluation of a human team training strategy

    E-Print Network [OSTI]

    Nikolaidis, Stefanos

    We design and evaluate human-robot cross-training, a strategy widely used and validated for effective human team training. Cross-training is an interactive planning method in which a human and a robot iteratively switch ...

  5. Environmental Public Health Performance Standards

    E-Print Network [OSTI]

    Environmental Public Health Performance Standards Environmental Health Program Self Agency: Total Environmental Health Program Budget: #12;Environmental Public Health Performance Standards (v. 2.0); Environmental Health Program Assessment Instrument, 1/7/2010 Page 2 Proportion

  6. Essays on health care delivery and financing

    E-Print Network [OSTI]

    Chan, David C. (David Cchimin)

    2013-01-01T23:59:59.000Z

    This thesis contains essays on health care delivery and financing. Chapter 1 studies the effect of organizational structure on physician behavior. I investigate this by studying emergency department (ED) physicians who ...

  7. This is your stream. This is your stream on drugs: Scientists' expanding research and technologies show that traces of pharmaceuticals in water may threaten aquatic health.

    E-Print Network [OSTI]

    Jordan, Leslie

    2010-01-01T23:59:59.000Z

    about effects these substances could have on public health? According to the current body of research, the answer is no. Should they be concerned about the impact on the fish, turtles, and aquatic life in those waterbodies? Maybe so. From... of wastewater treatment plants in Chicago, Dallas, Orlando, Fla., Phoenix, and West Chester, Pa., near Philadelphia. Isolated from human sources of con- tamination, the Gila River Wilderness Area in New Mexico was the study?s refer- ence site...

  8. Gender, social roles and health care utilization

    E-Print Network [OSTI]

    David, Jennifer Louise

    1992-01-01T23:59:59.000Z

    by the fixed role hypothesis. This analysis estimates a model according to which the gender differential in health care utilization is attributable to the mediating effects of gender influenced social roles and the resources and psycho-social dispositions... to physical symptoms. The present analysis esumates a model according to which the gender differential in health care utilization is attributable to the mediating effects of gender influenced social roles and associated resources and dispositions...

  9. Cost-effective facility disposition planning with safety and health lessons learned and good practices from the Oak Ridge Decontamination and Decommissioning Program

    SciTech Connect (OSTI)

    NONE

    1998-05-01T23:59:59.000Z

    An emphasis on transition and safe disposition of DOE excess facilities has brought about significant challenges to managing worker, public, and environmental risks. The transition and disposition activities involve a diverse range of hazardous facilities that are old, poorly maintained, and contain radioactive and hazardous substances, the extent of which may be unknown. In addition, many excess facilities do not have historical facility documents such as operating records, plant and instrumentation diagrams, and incident records. The purpose of this report is to present an overview of the Oak Ridge Decontamination and Decommissioning (D and D) Program, its safety performance, and associated safety and health lessons learned and good practices. Illustrative examples of these lessons learned and good practices are also provided. The primary focus of this report is on the safety and health activities and implications associated with the planning phase of Oak Ridge facility disposition projects. Section 1.0 of this report provides the background and purpose of the report. Section 2.0 presents an overview of the facility disposition activities from which the lessons learned and good practices discussed in Section 3.0 were derived.

  10. Graduate School of Public Health (Graduate School of Public Health) (Dept. of Public Health)`

    E-Print Network [OSTI]

    Kim, Guebuem

    including environmental health covering concept of contents and meanings. (Health Care Management-3-0 History of Health & Medical Care , , . , , , . This course reviews Graduate School of Public Health #12;#12;(Graduate School of Public Health) (Dept. of Public

  11. Environment, Safety and Health Reporting

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2012-01-01T23:59:59.000Z

    To ensure timely collection, reporting, analysis, and dissemination of information on environment, safety, and health issues as required by law or regulations or as needed to ensure that the Department of Energy (DOE) and National Nuclear Security Administration are kept fully informed on a timely basis about events that could adversely affect the health and safety of the public or the workers, the environment, the intended purpose of DOE facilities, or the credibility of the Department. Cancels DOE O 210.1, DOE O 231.1, DOE O 232.1A. Canceled by DOE O 231.1B. DOE O 231.1B cancels all portions pertaining to environment, safety, and health reporting. Occurrence reporting and processing of operations information provisions remain in effect until January 1, 2012.

  12. Environment, Safety, and Health Risk Assessment Program (ESHRAP)

    SciTech Connect (OSTI)

    Eide, Steven Arvid; Thomas Wierman

    2003-12-01T23:59:59.000Z

    The Environment, Safety and Health Risk Assessment Program (ESHRAP) models human safety and health risk resulting from waste management and environmental restoration activities. Human safety and health risks include those associated with storing, handling, processing, transporting, and disposing of radionuclides and chemicals. Exposures to these materials, resulting from both accidents and normal, incident-free operation, are modeled. In addition, standard industrial risks (falls, explosions, transportation accidents, etc.) are evaluated. Finally, human safety and health impacts from cleanup of accidental releases of radionuclides and chemicals to the environment are estimated. Unlike environmental impact statements and safety analysis reports, ESHRAP risk predictions are meant to be best estimate, rather than bounding or conservatively high. Typically, ESHRAP studies involve risk predictions covering the entire waste management or environmental restoration program, including such activities as initial storage, handling, processing, interim storage, transportation, and final disposal. ESHRAP can be used to support complex environmental decision-making processes and to track risk reduction as activities progress.

  13. Roadmap: Integrated Health Studies -Health Sciences Bachelor of Science

    E-Print Network [OSTI]

    Sheridan, Scott

    Six: [14 Credit Hours] NURS 45010 Health Care Policy and Delivery Systems or NURS 46000 Health Care 41581 Health Psychology (3) or SOC 42563 Sociology in Health and Health Care (3) 3 Health Science 45080 Physiology of Exercise 3 PHIL 40005 Health Care Ethics 3 General Elective (lower or upper

  14. Remote Structural Health Monitoring Systems for Next Generation SCADA

    E-Print Network [OSTI]

    Chou, Pai H.

    Remote Structural Health Monitoring Systems for Next Generation SCADA Sehwan Kim1 Marco Torbol2, and to validate its effectiveness with long-term field deployment results. Keywords: structural health monitoring, SCADA system, remote monitoring system 1. INTRODUCTION Structural health monitoring (SHM) is the use

  15. Structural health monitoring sensor development for the Imote2 platform

    E-Print Network [OSTI]

    Spencer Jr., B.F.

    Structural health monitoring sensor development for the Imote2 platform Jennifer A. Rice*a and B motivated researchers to seek effective methods for real-time structural health monitoring (SHM that is necessary to successfully implement SHM algorithms. Keywords: Structural health monitoring, smart sensor

  16. Human Ecology Human ecology Research

    E-Print Network [OSTI]

    Wang, Z. Jane

    Channel, Latin America. STUDIOS Architecture. #12;HUMAN ECOLOGY · APRIL 2005 1 Lisa Staiano-Coico, Ph Frey spins a green alternative for textiles. Fibers from rapidly renewable materials

  17. Bioelectromagnetic effects of the electromagnetic pulse (EMP)

    SciTech Connect (OSTI)

    Patrick, E.L.; Vault, W.L.

    1990-03-01T23:59:59.000Z

    The public has expressed concern about the biological effects and hazards of non-ionizing electromagnetic fields produced by the electro-magnetic pulse (EMP) simulators that simulate the EMP emanating from a high-altitude nuclear explosion. This paper provides a summary of the bioelectromagnetic effects literature up through the present, describes current occupational standards for workers exposed to the EMP environment, and discusses the use of medical surveillance as it relates to the potential human health hazards associated with exposure to the EMP environment.

  18. The effect of a controlled manipulation of maternal dietary fat intake on medium and long chain fatty acids in human breast milk in Saskatoon, Canada

    E-Print Network [OSTI]

    Nasser, Roseann; Stephen, Alison M; Goh, Yeow K; Clandinin, M Thomas

    2010-02-19T23:59:59.000Z

    Nutr Soc 2007, 66:397-404. 2. Hachey DL, Thomas MR, Emken EA, Garza C, Brown-Booth L, Adlof RO, Klein PD: Human lactation: maternal transfer to dietary triglycerides labeled with stable isotopes. J Lipid Res 1987, 28:1185-1192. 3. Emken EA, Adlof RO... . Within-feed and between-breast variation in selected components of human milk. Am J Clin Nutr 1984, 40:635-646. 20. Jensen RG: Determination of lipid content. The Lipids of Human Milk Boca Raton: CRC PressJensen RG 1989, 25-41. 21. Hall B: Uniformity...

  19. BIOMEDICAL AND HEALTH Assessing the Environmental, Health

    E-Print Network [OSTI]

    Magee, Joseph W.

    BIOMEDICAL AND HEALTH Assessing the Environmental, Health and Safety Impact of Nanoparticles are urgently needed to support risk assessments and regulatory policy decisions regarding materials containing · Environmental Protection Agency · DuPont · BASF · Evonik · Cabot · General Electric Approach The quartz crystal

  20. CANDU human performance analysis

    SciTech Connect (OSTI)

    Walker, I.

    1987-01-01T23:59:59.000Z

    An evaluation of human performance is presented in this paper in the context of the operational safety management system. To focus on problems, an experience review program has been developed to establish trends, demonstrate the degree of compliance with standards, and determine the causes of poor performance. The primary method by which the experience review takes place is significant event reporting (SER). A significant event is an incident that causes an undesirable effect on safety, product quality, environmental protection, or product cost. In spite of advanced technology and the degree of automation of the Canada deuterium uranium (CANDU) design, mistakes and malfunctions to occur. Considerable effort has been made to prevent or reduce the incidence of error. The Institute of Nuclear Power Operations developed a system to analyze human error, called the Human Performance Evaluation System (HPES). To encourage an open exchange of information, the system is anonymous and nonpunitive. All data gathered during HPES evaluations are kept confidential.

  1. Anti-Tumor Effect in Human Lung Cancer by a Combination Treatment of Novel Histone Deacetylase Inhibitors: SL142 or SL325 and Retinoic Acids

    E-Print Network [OSTI]

    2010-01-01T23:59:59.000Z

    of a K-ras ribozyme against human lung cancer cell lineHeymach JV, Lippman SM (2008) Lung cancer. N Engl J Med 359:for advanced non-small cell lung cancer. J Thorac Oncol 2:

  2. Evidence of Southern Health

    E-Print Network [OSTI]

    Acton, Scott

    POS Evidence of Coverage Southern Health Services, Inc. SH.POS.11-09 #12;Table of Contents SH................................................................................................10 Facts about Southern Health .....................................................................12 Members' Responsibilities to Know How and When to Seek Care ............................13 Section

  3. Policy Title: Human Subject Responsible Office: UFS

    E-Print Network [OSTI]

    Chen, Yiling

    Policy Title: Human Subject Payments Responsible Office: UFS HARVARD UNIVERSITY FINANCIAL POLICY Effective Date: 1/1/11 Revision Date: N/A HUMAN SUBJECT PAYMENTS Policy Number TAX102 HARVARD UNIVERSITY FINANCIAL POLICY POLICY STATEMENT Individuals conducting Harvard research studies that compensate human

  4. ORISE: Health Promotion and Outreach

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Health Promotion and Outreach Health Promotion & Outreach The Oak Ridge Institute for Science and Education (ORISE) provides health promotion and outreach support to government...

  5. Open Defecation and the Human Waste Crisis in India

    E-Print Network [OSTI]

    Mozaffar, Parveen

    2014-05-31T23:59:59.000Z

    This thesis analyzes the human waste crisis in India. The lack of sanitation facilities as well as open defecation seriously impacts India's ability to achieve its sanitation goals by 2015. More importantly, if the World Health Organization...

  6. Comparative Genomic Analysis of Human Fungal Pathogens Causing Paracoccidioidomycosis

    E-Print Network [OSTI]

    Holder, Jason W.

    Paracoccidioides is a fungal pathogen and the cause of paracoccidioidomycosis, a health-threatening human systemic mycosis endemic to Latin America. Infection by Paracoccidioides, a dimorphic fungus in the order Onygenales, ...

  7. Surveillance study of health effects associated with cleanup of a hazardous waste site, Ralph Gray Trucking Company (a/k/a Westminster Tract Number 2633), Westminster, Orange County, California, Region 9: CERCLIS number CAD981995947

    SciTech Connect (OSTI)

    Hoshiko, S.; Underwood, M.C.; Smith, D.; DeLorenze, G.; Neuhaus, J.

    1999-04-01T23:59:59.000Z

    Excavation of a Superfund site, the Ralph Gray Truncking Company located in Westminster Orange County, California was anticipated to release sulfur dioxide and other chemicals. The California Department of Health Services, under cooperative agreement with the Agency for Toxic Substances and Disease Registry, conducted a surveillance study to assess whether illnesses were associated with cleanup activities. A panel primarily composed of more sensitive persons (n = 36) was selected to report daily respiratory symptoms and odors. Exposures included sulfur dioxide (SO{sub 2}) measurements and daily tonnage of waste removed. Analysis used Conditional Likelihood Regression and Generalized Estimating Equations (GEE) methods. Levels of SO{sub 2} were generally higher than usual ambient air, at times exceeding levels which can cause health effects among asthmatics in laboratory settings. Wheeze and cough were significantly associated with tonnage of waste removed, especially on days when the highest amounts of waste were removed. Upper respiratory symptoms were found to be associated with SO{sub 2}, and weak relationships were found with nausea and burning nose and SO{sub 2}.

  8. Environmental Health & Safety

    E-Print Network [OSTI]

    Environmental Health & Safety Sub Department Name 480 Oak Rd, Stanford, CA 94305 T 650.723.0448 F 650.725.3468 DEPUTY DIRECTOR, ENVIRONMENTAL HEALTH AND SAFETY Exempt, Full-Time (100% FTE) Posted May 1, 2014 The Department of Environmental Health and Safety (EH&S) at Stanford University seeks

  9. Health Insurance Marketplace

    E-Print Network [OSTI]

    Acton, Scott

    options. You may be able to get coverage now through existing programs. Visit HealthCare.gov to learn more, and coinsurance. You'll want to consider these details while you're exploring your options. Visit HealthCare will offer essential health benefits, including doctor visits, preventive care, hospitalization

  10. Being Interactive Health Care

    E-Print Network [OSTI]

    Being Interactive Treating Health Care T he numbers are staggering. In a chilling report, the U care, training staff, and accrediting staff and health-care facilities, which involve determin- ing.ahrq.gov/clinic/ptsafety/summary.htm). Pressures on Health Care To come up with a credible approach for improv- ing patient safety, we need

  11. Global Health Seminar Series

    E-Print Network [OSTI]

    Klein, Ophir

    Bay Area Global Health Seminar Series Monday, January 27, 2014 2:30pm ­ 4:00pm (Reception to follow at the Center for Health Policy and the Woods Institute for the Environment. He studies how economic, political, and natural environments affect population health in developing countries using a mix of experimental

  12. Health Psychology Chapter Eleven

    E-Print Network [OSTI]

    Meagher, Mary

    % of health care research focuses on mortality or physiological indicators of morbidity to determine treatmentHealth Psychology Chapter Eleven: Management of Chronic Illness #12;Quality of Life: What outcome. #12;Kaplan's Model Argues that the most important indicators of health and wellness

  13. HEALTH CARE ASSOCIATION

    E-Print Network [OSTI]

    Leistikow, Bruce N.

    HEALTH CARE COMPLIANCE ASSOCIATION 5780 Lincoln Drive · Suite 120 · Minneapolis, MN 55436 · 888 of the following document, "Evaluating and Improving a Compliance Program, A Resource for Health care Board Members, Health care Executives and Compliance Officers." This resource is now available to all HCCA members

  14. Public Health FAT FACTORS

    E-Print Network [OSTI]

    Qian, Ning

    : THE UNITED STATES SPENDS MORE ON HEALTH CARE THAN ANY OTHER COUNTRY. YET WE CONTINUE TO FALL FAR BEHIND States spends an astonishing percent of our gross domestic product on health care--significantly moreColumbia Public Health HOT TOPIC Climate Change FAT FACTORS Obesity Prevention BOOK SMART

  15. Student Health Benefit Plan

    E-Print Network [OSTI]

    Massachusetts at Amherst, University of

    and programs tailored to the needs of students. The SHBP coordinates care with University Health Services (UHS), UMass Amherst's fully accredited health center. UHS provides comprehensive primary care, walk-in care2 2013-2014 Student Health Benefit Plan (SHBP) Designed for the Students of Policy Period: August 1

  16. STUDENT MENTAL HEALTH POLICY

    E-Print Network [OSTI]

    Martin, Ralph R.

    pastoral care as well as teaching Take positive steps to promote students well-being Ensure the health students to make contact with their GP or local mental health services. The Duty of Care and Negligence1 STUDENT MENTAL HEALTH POLICY Revised January 2013 #12;2 A. INTRODUCTION 1. Context Widening

  17. Horizon Health EAP Services

    E-Print Network [OSTI]

    Yates, Andrew

    /09) HorizonCareLinkSM ­ All the help you need online Horizon Health EAP also provides services through counselors- Child care or elder care services- Pet care and veterinarians- Adoption resources- Health clubsHorizon Health EAP Services Employee Assistance Program with Telephone and 3 Face

  18. PRIVACY OF HEALTH INFORMATION

    E-Print Network [OSTI]

    and civil fraud and abuse regulations. Finally, HIPAA was intended to streamline the health care system through the adoption of consistent standards for transmitting uniform electronic health care data between providers of health care services (e.g. MCW) and payers (e.g. Medicare). In order to adopt transmission

  19. PUBLIC HEALTH Noroviruses

    E-Print Network [OSTI]

    Massachusetts at Amherst, University of

    under special circumstances. Usually, health care providers will first try to rule out other germs or worsen, contact your health care provider. #12;What can you do to prevent NLV infection? Follow the tips), or the diarrhea is very bad, call your health care provider for advice. Are there any restrictions for people

  20. Human energy

    E-Print Network [OSTI]

    Sawyer, Suzana

    2010-01-01T23:59:59.000Z

    through emotive cinematography and narrative that situatethe effect, using the cinematography of Lance Acord (of ‘‘

  1. Millersville University Health Services Confidentiality and Privacy of Health Information

    E-Print Network [OSTI]

    Hardy, Christopher R.

    will share your health information with other designated business associates (ie: laboratories, radiology facilities) o Health Services may use and disclose health information to contact you o Health Services may

  2. Leadership in Health Care Systems: Health Care Organization Management

    E-Print Network [OSTI]

    Goldman, Steven A.

    Leadership in Health Care Systems: Health Care Organization Management and Leadership Track: ­ Health Care Organization, Management and Leadership ­ Clinical Research Coordinator ­ Clinical Nurse in health care ethics ­ Public mission ­ Fiscal stewardship ­ Inclusiveness and diversity ­ Theory based

  3. The Local Board of Health Environmental Health Primer

    E-Print Network [OSTI]

    The Local Board of Health Environmental Health Primer Risk Assessment Factsheet environmental,M.,andToscano,W.(Eds).(2007).Risk Assessment for Environmental Health. · NationalAssociationofLocalBoardsofHealth.(2011).RiskAssessment assessment

  4. The South African Disease: Apartheid Health and Health Services by Cedric de Beer

    E-Print Network [OSTI]

    Robb, Judith

    1988-01-01T23:59:59.000Z

    Apartheid Health and Health Services. Trenton, N.J. :Given that health and health services are directly relatedApartheid Health and Health Services, examines the truth of

  5. Certification of Health Care Provider for Employee's Serious Health Condition

    E-Print Network [OSTI]

    Subramanian, Venkat

    of Health Care Provider for Employee's Serious Health Condition (Family and Medical Leave Act) SECTION I health condition to submit a medical certification issued by the employee's health care provider. Please: __________________________________________________________________________________ First Middle Last SECTION III: For Completion by the HEALTH CARE PROVIDER INSTRUCTIONS to the HEALTH

  6. National Center for Environmental Health Division of Emergency and Environmental Health Services

    E-Print Network [OSTI]

    develop effective state-of-the-art environmental public health programs. Grantees implement interventions disparities in the communities they serve. Get information about grantees and their products at http:// www

  7. Direct from CDC Environmental Health

    E-Print Network [OSTI]

    health specialists atAColorado's Tri-County Health Department, as well as at health departments in other, and Douglas counties, and have become more engaged in city planning. Tri-County's environmental health special

  8. Sun Life Financial (Sun Life) Benefit Adjudication Effective December 1, 2008, Sun Life became the health and dental benefits carrier for active

    E-Print Network [OSTI]

    Sun Life Financial (Sun Life) Benefit Adjudication Effective December 1, 2008, Sun Life became to maintain the level of benefits coverage with Sun Life. Sun Life has identified a number of GWL practices not been processed by Sun Life The Pension & Benefits office was advised by GWL that they would process all

  9. Representative Seroprevalences of Brucellosis in Humans and Livestock in Kyrgyzstan

    E-Print Network [OSTI]

    Richner, Heinz

    Representative Seroprevalences of Brucellosis in Humans and Livestock in Kyrgyzstan Bassirou Bonfoh), 60 Togolok Moldo Street, Bishkek, Kyrgyzstan 3 Veterinary Public Health Institute, Vetsuisse Faculty, Swiss Red Cross, 187/1 Sydykova Street, Bishkek, Kyrgyzstan 5 Swiss Tropical and Public Health Institute

  10. Drug-free Workplace Policy Responsible Administrative Unit: Human Resources

    E-Print Network [OSTI]

    .0 BACKGROUND AND PURPOSE Mines is committed to protecting the health, safety and well-being of all employees significant health, safety and well-being concerns within the Mines working and learning environment. 1 Institutional Alcohol Policy. #12;Drug-free Workplace Policy Responsible Administrative Unit: Human Resources

  11. Can you recognize victims of human trafficking among the

    E-Print Network [OSTI]

    Kay, Mark A.

    signs of physical abuse and torture · Substance abuse or addictions · Malnourishment and serious dental, phobias and panic attacks Preventive health care for victims of human trafficking is virtually non their lives by connecting them to basic services related to: · Housing · Health care · Immigration assistance

  12. Indoor Air Nuclear, Biological, and Chemical Health Modeling and Assessment System

    SciTech Connect (OSTI)

    Stenner, Robert D.; Hadley, Donald L.; Armstrong, Peter R.; Buck, John W.; Hoopes, Bonnie L.; Janus, Michael C.

    2001-03-01T23:59:59.000Z

    Indoor air quality effects on human health are of increasing concern to public health agencies and building owners. The prevention and treatment of 'sick building' syndrome and the spread of air-borne diseases in hospitals, for example, are well known priorities. However, increasing attention is being directed to the vulnerability of our public buildings/places, public security and national defense facilities to terrorist attack or the accidental release of air-borne biological pathogens, harmful chemicals, or radioactive contaminants. The Indoor Air Nuclear, Biological, and Chemical Health Modeling and Assessment System (IA-NBC-HMAS) was developed to serve as a health impact analysis tool for use in addressing these concerns. The overall goal was to develop a user-friendly fully functional prototype Health Modeling and Assessment system, which will operate under the PNNL FRAMES system for ease of use and to maximize its integration with other modeling and assessment capabilities accessible within the FRAMES system (e.g., ambient air fate and transport models, water borne fate and transport models, Physiologically Based Pharmacokinetic models, etc.). The prototype IA-NBC-HMAS is designed to serve as a functional Health Modeling and Assessment system that can be easily tailored to meet specific building analysis needs of a customer. The prototype system was developed and tested using an actual building (i.e., the Churchville Building located at the Aberdeen Proving Ground) and release scenario (i.e., the release and measurement of tracer materials within the building) to ensure realism and practicality in the design and development of the prototype system. A user-friendly "demo" accompanies this report to allow the reader the opportunity for a "hands on" review of the prototype system's capability.

  13. Health risk assessment of environmental exposure to 1,1,1-trichloroethane

    SciTech Connect (OSTI)

    Verschuuren, H.G.; de Rooij, C.G. (Dow Europe, Horgen (Switzerland))

    1990-02-01T23:59:59.000Z

    In 1986 a survey was published by CEFIC on the occurrence of chlorinated solvents in ambient air, in surface water, and in ground water. The present article concentrates on 1,1,1-trichloroethane (1,1,1-T), and puts into perspective the environmental occurrence and the toxicity. Critical toxicological data are briefly discussed. As no evidence of a carcinogenic effect of 1,1,1-T is apparent, the no-adverse-effect levels in chronic inhalation exposure in rats (875 ppm) and mice (1500 ppm) form the basis for the estimation of potential risk to human health. Environmental exposure to 1,1,1-T is mainly via the atmosphere (120 micrograms/day); the contributions of drinking water (2 micrograms/day) and food (3 micrograms/kg) are negligible. Safety margins are calculated by comparing the no-adverse-effect levels in rat and mouse studies with the total body burden. Safety margins are also calculated after converting no-adverse-effect levels into estimated internal dose levels by physiologically based pharmacokinetic modeling. Safety margins vary with the starting point, but are of the order of 10(5) for the general population and more than 10(4) for the population close to industrial activities. It may be concluded that the risk of a potential health effect resulting from environmental exposure to 1,1,1-trichloroethane is negligible. 43 references.

  14. Biomedical Sciences Contributing to Progress in Human

    E-Print Network [OSTI]

    Huang, Jianwei

    Biomedical Sciences Contributing to Progress in Human Health as a Leading Integrated Research and global impact. The University also strives to complement this breadth of scholarship with focus Medicine, Nature Genetics, Lancet and Science ­ Contribution to 68 out of the 395 `top' papers from

  15. Health physics and public health activities at hazardous wastes sites

    SciTech Connect (OSTI)

    Charp, P.A. [Agency for Toxic Substances and Disease Registry, Atlanta, GA (United States)

    1995-12-31T23:59:59.000Z

    The Agency for Toxic Substances and Disease Registry (ATSDR) has worked with the U.S. Environmental Protection Agency (EPA) at several sites contaminated with radioactive materials. The Navajo Brown Vandever (B-V) uranium mine site near Bluewater, New Mexico, and the Austin Avenue Radiation Site (AAR) in Lansdowne, Pennsylvania were the subject of ATSDR health advisories. The sites were contamined with uranium or uranium byproducts but the identification of potential health effects and actions taken to prevent or reduce exposures were approached from different perspectives. At B-V contaminants included uranium and mine tailings, radium, and radon. Contaminants at the site and physical hazards were removed. At AAR, radium and radon were located in residential settings. Residents who might have had annual exposures greater than accepted standards or recommendations were relocated and contaminated building demolished.

  16. Roadmap: Public Health Health Services Administration Bachelor of Science in Public Health

    E-Print Network [OSTI]

    Sheridan, Scott

    and Control of Diseases 3 PH 30012 Communicable Diseases 3 PH 30015 United States Health Care System 3 42086 Economics of Health Care 3 PHIL 40005 Health Care Ethics 3 PH 40092 Internship in Public Health* 3 Sociology of Health and Health Care 3 *Fulfills ELR Ken

  17. The function of the clinic is to provide high-quality, low-cost mental health services for the

    E-Print Network [OSTI]

    Dyer, Bill

    The function of the clinic is to provide high- quality, low-cost mental health services in mental health and marriage and family counseling obtain clinical experience. Student counselors the Human Development CliniDevelopment Clinic . . .c . . . Human Development Clinic 1501 S. 3rd Ave

  18. Center for Biomedical Ethics and Humanities University of Virginia School of Medicine

    E-Print Network [OSTI]

    Acton, Scott

    , 5:00 pm, Jordan Conference Center Auditorium Health Care Reform and End-of-Life Care Amy P-presented with the Institute for Practical Ethics and Public Life 7 October 2009 Queer Health Care: LGBTI Patients Foundation for the Humanities, History of the Health Sciences Lecture Series, and Buckner W. Clay Endowment

  19. Mobile phone and my health

    SciTech Connect (OSTI)

    Surducan, Aneta [Nicolae Balcescu High School, 6 Constanta St., 400158 Cluj-Napoca (Romania)] [Nicolae Balcescu High School, 6 Constanta St., 400158 Cluj-Napoca (Romania); Dabala, Dana [National Railways Medical Clinic,, Occupational Medicine Department, 16-20 Republicii St., 400015 Cluj-Napoca (Romania)] [National Railways Medical Clinic,, Occupational Medicine Department, 16-20 Republicii St., 400015 Cluj-Napoca (Romania); Neamtu, Camelia, E-mail: emanoil.surducan@itim-cj.ro; Surducan, Vasile, E-mail: emanoil.surducan@itim-cj.ro; Surducan, Emanoil, E-mail: emanoil.surducan@itim-cj.ro [National Institute for Research and Development of Isotopic and Molecular Technologies, 65-103 Donath St., 400293 Cluj-Napoca (Romania)] [National Institute for Research and Development of Isotopic and Molecular Technologies, 65-103 Donath St., 400293 Cluj-Napoca (Romania)

    2013-11-13T23:59:59.000Z

    The interaction of the microwave radiation emitted by mobile phones with the user's body is analyzed from the International Commission on Non-Ionizing Radiation Protection (ICNIRP) recommendations perspective as a correlation between the specific absorption ratio (SAR) of the mobile phone and the call duration. The relative position of the cell phone to the user's body, the dielectric properties of the exposed body parts, the SAR value and the call duration are considered in the local body temperature rise due to the microwave heating effect. The recommended local temperature rise limit in the human body is evaluated according to standards. The aim of this study is to disseminate information to young people, especially high school students, about the microwave thermal effects on the human body, to make them aware of the environmental electromagnetic pollution and to offer them a simple method of biological self protection.

  20. Development and Health The impact of health on development in

    E-Print Network [OSTI]

    Glasgow, University of

    · breakdown of health care delivery systems · inadequate application of TB control measures · increasing drug's population are at risk - increasing due to: · breakdown of health care delivery systems · growing drugDevelopment and Health The impact of health on development in Africa #12;Health challenges

  1. Chapter 1: What is Health Psychology Health Psychology &

    E-Print Network [OSTI]

    Meagher, Mary

    ) and correlations of health, illness and dysfunction 4. Improving the health care system and formulating health #12 Descartes: Interactionism #12;Models of Health Care: Biomedical Model Focus on illness Dominant model Health Care Costs Outcomes Research Rise of the Biopsychosocial Model #12;The Mind-Body Relationship

  2. UNIVERSITY OF FLORIDA COLLEGE OF PUBLIC HEALTH AND HEALTH PROFESSIONS

    E-Print Network [OSTI]

    Kane, Andrew S.

    and ideas concerning the organization of the public health and medical care systems COURSE of the health care system and the interaction of providers (hospitals, physicians, etc), patients, and sources of health care financing (Medicaid, private health insurance etc) The historical development of the health

  3. Chapter 1: What is Health Psychology Health Psychology &

    E-Print Network [OSTI]

    Meagher, Mary

    of health, illness and dysfunction 4. Improving the health care system and formulating health #12;The Mind of Health Care: Biomedical Model ! Focus on illness ! Dominant model for the past 300 years ! All illness://www.sas.upenn.edu/~hatfield/ #12;! Changing Patterns of Illness! ! Escalating Health Care Costs! ! ! Outcomes Research! Rise

  4. Chapter 1: What is Health Psychology Health Psychology &

    E-Print Network [OSTI]

    Meagher, Mary

    . Improving the health care system and formulating health #12;The Mind-Body Relationship: A Brief History basis for diagnosis #12;Rene Descartes: Interactionism #12;Models of Health Care: Biomedical Model FocusChapter 1: What is Health Psychology Health Psychology & Behavioral Medicine Psyc 360 Dr. Meagher

  5. Health and Wellness @ U.Va. Department of Student Health

    E-Print Network [OSTI]

    Acton, Scott

    Health and Wellness @ U.Va. Department of Student Health Counseling and Psychological Services "Without health there is no happiness. An attention to health, then, should take the place of every other on Accreditation of Healthcare Organizations 2013 Parents Handbook p. 36-41 #12;Student Health Services · 12:30am-2

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    E-Print Network [OSTI]

    Oliver, Douglas L.

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  7. 2012 Environmental Performance Index: Environmental Health Objective The 2012 EPI builds on measures relevant to the goal of reducing environmental

    E-Print Network [OSTI]

    Columbia University

    2012 Environmental Performance Index: Environmental Health Objective The 2012 EPI builds on measures relevant to the goal of reducing environmental stresses to human health, which are grouped into one objective category named environmental health. The objective weight is 30% of the overall EPI

  8. Grant Title: AHRQ HEALTH SERVICES RESEARCH DEMONSTRATION AND DISSEMINATION GRANTS Funding Opportunity Number: PA-13-046. CFDA Number(s): 93.226.

    E-Print Network [OSTI]

    Farritor, Shane

    Opportunity Number: PA-13-046. CFDA Number(s): 93.226. Agency/Department: Department of Health and Human

  9. Grant Title: MENTAL HEALTH RESEARCH DISSERTATION GRANT TO INCREASE DIVERSITY (R36) Funding Opportunity Number: PAR-12-103. CFDA Number(s): 93.242.

    E-Print Network [OSTI]

    Farritor, Shane

    Opportunity Number: PAR-12-103. CFDA Number(s): 93.242. Agency/Department: Department of Health and Human

  10. Effects

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville Power AdministrationField Campaign:INEA :Work4/11ComputationalEdNERSC:Effect of0/2002Effects of

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    E-Print Network [OSTI]

    health and counselling services health promotion 10 Ways to get active Most people find that power into your day. 1. take it outside. Ride a bike, go skating, fly a kite, throw a frisbee, kick chats for a power walk with friends and catch up face to face. 6. get involved locally. Join sports

  12. Health sciences Postgraduatecourses

    E-Print Network [OSTI]

    O'Mahony, Donal E.

    47 Cancer Care 47 Gerontological Nursing 48 Mental Health 49 Midwifery 51 Nursing 52 Palliative Care20 10 Health sciences Postgraduatecourses #12; Contents SCHOOL OF DENTAL SCIENCE 3 Named Degree Dentistry 6 Periodontics 6 Prosthodontics 7 Special Care Dentistry 8 Postgraduate Diplomas 9 Clinical

  13. Postgraduate Courses Health Sciences

    E-Print Network [OSTI]

    O'Mahony, Donal E.

    Cancer Care 49 Gerontological Nursing 50 Mental Health 51 Midwifery 53 Nursing 52 Palliative Care 552011 Postgraduate Courses Health Sciences #12; SCHOOL OF DENTAL SCIENCE 3 Named Degree Courses 4 Periodontics 6 Prosthodontics 7 Special Care Dentistry 8 Postgraduate Diplomas 9 Clinical Dental Technology 9

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    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville PowerCherries 82981-1cn SunnybankD.jpgHanford LEED&soilASTI-SORTIHealthHealth Effects

  15. Environmental Public Health Performance Standards

    E-Print Network [OSTI]

    Environmental Public Health Performance Standards (Version 2.0) Updated May 2014 National Center for Environmental Health Division of Emergency and Environmental Health Services #12;#12;Environmental Public Health Performance Standards (Version 2.0) Updated May 2014 #12;Environmental Public Health Performance Standards

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    Albrecht, David

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    Bandettini, Peter A.

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  18. Health Care Services Harvard Pilgrim

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    Lahav, Galit

    Health Care Services Harvard Pilgrim Health Care HMO 866-874-0817 www.harvardpilgrim.org Harvard Pilgrim Health Care POS 866-874-0817 www.harvardpilgrim.org Harvard University Group Health Program (HUGHP) HMO 617-495-2008 hughp.harvard.edu Harvard University Group Health Program (HUGHP) POS 617

  19. Mentoring Human Performance - 12480

    SciTech Connect (OSTI)

    Geis, John A.; Haugen, Christian N. [CALIBRE Systems, Inc., Alexandria, Virginia (United States)

    2012-07-01T23:59:59.000Z

    Although the positive effects of implementing a human performance approach to operations can be hard to quantify, many organizations and industry areas are finding tangible benefits to such a program. Recently, a unique mentoring program was established and implemented focusing on improving the performance of managers, supervisors, and work crews, using the principles of Human Performance Improvement (HPI). The goal of this mentoring was to affect behaviors and habits that reliably implement the principles of HPI to ensure continuous improvement in implementation of an Integrated Safety Management System (ISMS) within a Conduct of Operations framework. Mentors engaged with personnel in a one-on-one, or one-on-many dialogue, which focused on what behaviors were observed, what factors underlie the behaviors, and what changes in behavior could prevent errors or events, and improve performance. A senior management sponsor was essential to gain broad management support. A clear charter and management plan describing the goals, objectives, methodology, and expected outcomes was established. Mentors were carefully selected with senior management endorsement. Mentors were assigned to projects and work teams based on the following three criteria: 1) knowledge of the work scope; 2) experience in similar project areas; and 3) perceived level of trust they would have with project management, supervision, and work teams. This program was restructured significantly when the American Reinvestment and Recovery Act (ARRA) and the associated funding came to an end. The program was restructured based on an understanding of the observations, attributed successes and identified shortfalls, and the consolidation of those lessons. Mentoring the application of proven methods for improving human performance was shown effective at increasing success in day-to-day activities and increasing confidence and level of skill of supervisors. While mentoring program effectiveness is difficult to measure, and return on investment is difficult to quantify, especially in complex and large organizations where the ability to directly correlate causal factors can be challenging, the evidence presented by Sydney Dekker, James Reason, and others who study the field of human factors does assert managing and reducing error is possible. Employment of key behaviors-HPI techniques and skills-can be shown to have a significant impact on error rates. Our mentoring program demonstrated reduced error rates and corresponding improvements in safety and production. Improved behaviors are the result, of providing a culture with consistent, clear expectations from leadership, and processes and methods applied consistently to error prevention. Mentoring, as envisioned and executed in this program, was effective in helping shift organizational culture and effectively improving safety and production. (authors)

  20. Health Status and Health Literacy in Older Adults

    E-Print Network [OSTI]

    Fulton, Daphne Saxon

    2014-08-04T23:59:59.000Z

    This study aimed to examine the relationship between health literacy and the health status of older adults. The first section of the study consisted of a comprehensive literature review of prior research regarding cognitive, health, and behavioral...