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Note: This page contains sample records for the topic "human genome project" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
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We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


1

The human genome project  

SciTech Connect (OSTI)

The Human Genome Project will obtain high-resolution genetic and physical maps of each human chromosome and, somewhat later, of the complete nucleotide sequence of the deoxyribonucleic acid (DNA) in a human cell. The talk will begin with an extended introduction to explain the Project to nonbiologists and to show that map construction and sequence determination require extensive computation in order to determine the correct order of the mapped entities and to provide estimates of uncertainty. Computational analysis of the sequence data will become an increasingly important part of the project, and some computational challenges are described. 5 refs.

Bell, G.I.

1991-06-01T23:59:59.000Z

2

Genomics and the human genome project: implications for psychiatry  

E-Print Network [OSTI]

and psychosis: a convergent functional genomics approach.Physiology & Genomics, 4, 83–91. O LIPHANT , A. , B ARKER ,2004), 16(4), 294–300 Genomics and the Human Genome Project:

Kelsoe, J R

2004-01-01T23:59:59.000Z

3

Implications of the Human Genome Project  

SciTech Connect (OSTI)

The Human Genome Project (HGP), launched in 1991, aims to map and sequence the human genome by 2006. During the fifteen-year life of the project, it is projected that $3 billion in federal funds will be allocated to it. The ultimate aims of spending this money are to analyze the structure of human DNA, to identify all human genes, to recognize the functions of those genes, and to prepare for the biology and medicine of the twenty-first century. The following summary examines some of the implications of the program, concentrating on its scientific import and on the ethical and social problems that it raises. Its aim is to expose principles that might be used in applying the information which the HGP will generate. There is no attempt here to translate the principles into detailed proposals for legislation. Arguments and discussion can be found in the full report, but, like this summary, that report does not contain any legislative proposals.

Kitcher, P.

1998-11-01T23:59:59.000Z

4

Justice and the Human Genome Project  

SciTech Connect (OSTI)

Most of the essays gathered in this volume were first presented at a conference, Justice and the Human Genome, in Chicago in early November, 1991. The goal of the, conference was to consider questions of justice as they are and will be raised by the Human Genome Project. To achieve its goal of identifying and elucidating the challenges of justice inherent in genomic research and its social applications the conference drew together in one forum members from academia, medicine, and industry with interests divergent as rate-setting for insurance, the care of newborns, and the history of ethics. The essays in this volume address a number of theoretical and practical concerns relative to the meaning of genomic research.

Murphy, T.F.; Lappe, M. [eds.] [eds.

1992-12-31T23:59:59.000Z

5

Justice and the Human Genome Project  

SciTech Connect (OSTI)

Most of the essays gathered in this volume were first presented at a conference, Justice and the Human Genome, in Chicago in early November, 1991. The goal of the, conference was to consider questions of justice as they are and will be raised by the Human Genome Project. To achieve its goal of identifying and elucidating the challenges of justice inherent in genomic research and its social applications the conference drew together in one forum members from academia, medicine, and industry with interests divergent as rate-setting for insurance, the care of newborns, and the history of ethics. The essays in this volume address a number of theoretical and practical concerns relative to the meaning of genomic research.

Murphy, T.F.; Lappe, M. (eds.)

1992-01-01T23:59:59.000Z

6

Los Alamos Science: The Human Genome Project. Number 20, 1992  

SciTech Connect (OSTI)

This article provides a broad overview of the Human Genome Project, with particular emphasis on work being done at Los Alamos. It tries to emphasize the scientific aspects of the project, compared to the more speculative information presented in the popular press. There is a brief introduction to modern genetics, including a review of classic work. There is a broad overview of the Genome Project, describing what the project is, what are some of its major five-year goals, what are major technological challenges ahead of the project, and what can the field of biology, as well as society expect to see as benefits from this project. Specific results on the efforts directed at mapping chromosomes 16 and 5 are discussed. A brief introduction to DNA libraries is presented, bearing in mind that Los Alamos has housed such libraries for many years prior to the Genome Project. Information on efforts to do applied computational work related to the project are discussed, as well as experimental efforts to do rapid DNA sequencing by means of single-molecule detection using applied spectroscopic methods. The article introduces the Los Alamos staff which are working on the Genome Project, and concludes with brief discussions on ethical, legal, and social implications of this work; a brief glimpse of genetics as it may be practiced in the next century; and a glossary of relevant terms.

Cooper, N G; Shea, N [eds.

1992-01-01T23:59:59.000Z

7

The Human Genome Project: Information access, management, and regulation. Final report  

SciTech Connect (OSTI)

The Human Genome Project is a large, internationally coordinated effort in biological research directed at creating a detailed map of human DNA. This report describes the access of information, management, and regulation of the project. The project led to the development of an instructional module titled The Human Genome Project: Biology, Computers, and Privacy, designed for use in high school biology classes. The module consists of print materials and both Macintosh and Windows versions of related computer software-Appendix A contains a copy of the print materials and discs containing the two versions of the software.

McInerney, J.D.; Micikas, L.B.

1996-08-31T23:59:59.000Z

8

Entrepreneurial experiments in science policy: Analyzing the Human Genome Project  

E-Print Network [OSTI]

We re-conceptualize the role of science policy makers, envisioning and illustrating their move from being simple investors in scientific projects to entrepreneurs who create the conditions for entrepreneurial experiments ...

Huang, Kenneth G.

9

Getting the Word Out on the Human Genome Project: A Course for Physicians  

SciTech Connect (OSTI)

Our project, ''Getting the Word Out on the Human Genome Project: A Course for Physicians,'' presented educational goals to convey the power and promise of the Human Genome Program to a variety of professional, educational, and public audiences. Our initial goal was to provide practicing physicians with a comprehensive multimedia tool to update their skills in the genomic era. We therefore created the multimedia courseware, ''The New Genetics: Courseware for Physicians. Molecular Concepts, Applications, and Ramifications.'' However, as the project moved forward, several unanticipated audiences found the courseware to be useful for instruction and for self-education, so an additional edition of the courseware ''The New Genetics: Medicine and the Human Genome. Molecular Concepts, Applications, and Ramifications'' was published simultaneously with the physician version. At the time that both versions of the courseware were being completed, Stanford's Office of Technology Licensing opted not to commercialize the courseware and offered a license-back agreement if the authors founded a commercial business. The authors thus became closely involved in marketing and sales, and several thousand copies of the courseware have been sold. Surprisingly, the non-physician version has turned out to be more in demand, and this has led us in several new directions, most of which involve undergraduate education. These are discussed in detail in the Report.

Sara L. Tobin

2004-09-29T23:59:59.000Z

10

The human genome project: Information management, access, and regulation. Technical progress report, 1 April--31 August 1993  

SciTech Connect (OSTI)

Efforts are described to prepare educational materials including computer based as well as conventional type teaching materials for training interested high school and elementary students in aspects of Human Genome Project.

McInerney, J.D.; Micikas, L.B.

1993-09-10T23:59:59.000Z

11

The Human Genome Project and Mental Retardation: An Educational Program. Final Progress Report  

SciTech Connect (OSTI)

The Arc, a national organization on mental retardation, conducted an educational program for members, many of whom have a family member with a genetic condition causing mental retardation. The project informed members about the Human Genome scientific efforts, conducted training regarding ethical, legal and social implications and involved members in issue discussions. Short reports and fact sheets on genetic and ELSI topics were disseminated to 2,200 of the Arc's leaders across the country and to other interested individuals. Materials produced by the project can e found on the Arc's web site, TheArc.org.

Davis, Sharon

1999-05-03T23:59:59.000Z

12

Human Genome Program  

SciTech Connect (OSTI)

The DOE Human Genome program has grown tremendously, as shown by the marked increase in the number of genome-funded projects since the last workshop held in 1991. The abstracts in this book describe the genome research of DOE-funded grantees and contractors and invited guests, and all projects are represented at the workshop by posters. The 3-day meeting includes plenary sessions on ethical, legal, and social issues pertaining to the availability of genetic data; sequencing techniques, informatics support; and chromosome and cDNA mapping and sequencing.

Not Available

1993-01-01T23:59:59.000Z

13

ELSI Bibliography: Ethical legal and social implications of the Human Genome Project  

SciTech Connect (OSTI)

This second edition of the ELSI Bibliography provides a current and comprehensive resource for identifying publications on the major topics related to the ethical, legal and social issues (ELSI) of the Human Genome Project. Since the first edition of the ELSI Bibliography was printed last year, new publications and earlier ones identified by additional searching have doubled our computer database of ELSI publications to over 5600 entries. The second edition of the ELSI Bibliography reflects this growth of the underlying computer database. Researchers should note that an extensive collection of publications in the database is available for public use at the General Law Library of Los Alamos National Laboratory (LANL).

Yesley, M.S. [comp.

1993-11-01T23:59:59.000Z

14

Biology for Students: Bioinformatics The Human Genome Project (HGP) is an international effort to determine the biochemical code for  

E-Print Network [OSTI]

Biology for Students: Bioinformatics The Human Genome Project (HGP) is an international effort and their regulatory elements that serve as the blueprint of human biology. The HGP has generated massive data and high throughput fashion) and proteomics (analysis of the biological functions of gene products

Weng, Zhiping

15

Human genome. 1993 Program report  

SciTech Connect (OSTI)

The purpose of this report is to update the Human Genome 1991-92 Program Report and provide new information on the DOE genome program to researchers, program managers, other government agencies, and the interested public. This FY 1993 supplement includes abstracts of 60 new or renewed projects and listings of 112 continuing and 28 completed projects. These two reports, taken together, present the most complete published view of the DOE Human Genome Program through FY 1993. Research is progressing rapidly toward 15-year goals of mapping and sequencing the DNA of each of the 24 different human chromosomes.

Not Available

1994-03-01T23:59:59.000Z

16

ELSI Bibliography: Ethical, legal and social implications of the Human Genome Project. 1994 Supplement  

SciTech Connect (OSTI)

This report updates and expands the second edition of the ELSI Bibliography, published in 1993. The Bibliography and Supplement provides a comprehensive resource for identifying publications on the major topics related to the ethical, legal and social issues (ELSI) of the Human Genome Project. The Bibliography and Supplement are extracted from a database compiled at Los Alamos National Laboratory with the support of the Office of Energy Research, US Department of Energy. The second edition of the ELSI Bibliography was dated May 1993 but included publications added to the database until fall 1993. This Supplement reflects approximately 1,000 entries added to the database during the past year, bringing the total to approximately 7,000 entries. More than half of the new entries were published in the last year, and the remainder are earlier publications not previously included in the database. Most of the new entries were published in the academic and professional literature. The remainder are press reports from newspapers of record and scientific journals. The topical listing of the second edition has been followed in the Supplement, with a few changes. The topics of Cystic Fibrosis, Huntington`s Disease, and Sickle Cell Anemia have been combined in a single topic, Disorders. Also, all the entries published in the past year are included in a new topic, Publications: September 1993--September 1994, which provides a comprehensive view of recent reporting and commentary on the science and ELSI of genetics.

Yesley, M.S.; Ossorio, P.N. [comps.

1994-09-01T23:59:59.000Z

17

Whitehead Policy Symposium. The Human Genome Project: Science, law, and social change in the 21st century  

SciTech Connect (OSTI)

Advances in the biomedical sciences, especially in human genomics, will dramatically influence law, medicine, public health, and many other sectors of our society in the decades ahead. The public already senses the revolutionary nature of genomic knowledge. In the US and Europe, we have seen widespread discussions about genetic discrimination in health insurance; privacy issues raised by the proliferation of DNA data banks; the challenge of interpreting new DNA diagnostic tests; changing definitions of what it means to be healthy; and the science and ethics of cloning animals and human beings. The primary goal of the Whitehead/ASLME Policy Symposium was to provide a bridge between the research community and professionals, who were just beginning to grasp the potential impact of new genetic technologies on their fields. The ''Human Genome Project: Science, Law, and Social Change in the 21st Century'' initially was designed as a forum for 300-500 physicians, lawyers, consumers, ethicists, and scientists to explore the impact of new genetic technologies and prepare for the challenges ahead.

Nichols, E.K.

2000-02-17T23:59:59.000Z

18

The New World of Human Genetics: A dialogue between Practitioners & the General Public on Ethical, Legal & Social Implications of the Human Genome Project  

SciTech Connect (OSTI)

The history and reasons for launching the Human Genome project and the current uses of genetic human material; Identifying and discussing the major issues stemming directly from genetic research and therapy-including genetic discrimination, medical/ person privacy, allocation of government resources and individual finances, and the effect on the way in which we perceive the value of human life; Discussing the sometimes hidden ethical, social and legislative implications of genetic research and therapy such as informed consent, screening and preservation of genetic materials, efficacy of medical procedures, the role of the government, and equal access to medical coverage.

Schofield, Amy

2014-12-08T23:59:59.000Z

19

Use of Optical Mapping to Aid in Assembly and Finishing of Human Microbiome Genome Projects  

SciTech Connect (OSTI)

Trevor Wagner of OpGen, Inc. discusses the use of optical mapping to validate the assembly of HMP genomes on June 3, 2010 at the "Sequencing, Finishing, Analysis in the Future" meeting in Santa Fe, NM

Wagner, Trevor [OpGen, Inc

2010-06-03T23:59:59.000Z

20

An information and dialogue conference on the human genome project (HGP) for the minority communities in the state of Louisiana  

SciTech Connect (OSTI)

Zeta Phi Beta Sorority National Educational Foundation, in cooperation with Xavier University of New Orleans, and the New Orleans District Office of the United States Equal Employment Opportunity Commission, held the Information and Dialogue Conference on the Human Genome Project for the Minority Communities in the State of Louisiana on April 16-17, 1999. The Conference was held on the campus of Xavier University in New Orleans. Community leaders, government officials, minority professional and social organizations leaders, religious leaders, persons from the educational and academic community, and students were invited. Conference objectives included bringing HGP information and a focus in the minority community on the project, in clear and understandable terms, to spread the work in the minority community about the project; to explore the likely positive implications with respect to health care and related matters; to explore possible negative results and strategies to meet them; to discuss the social, legal, and ethical implications; and to facilitate minority input into the HGP as it develops.

NONE

1999-06-01T23:59:59.000Z

Note: This page contains sample records for the topic "human genome project" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


21

The Consensus Coding Sequence (Ccds) Project: Identifying a Common Protein-Coding Gene Set for the Human and Mouse Genomes  

E-Print Network [OSTI]

Effective use of the human and mouse genomes requires reliable identification of genes and their products. Although multiple public resources provide annotation, different methods are used that can result in similar but ...

Kellis, Manolis

22

Human Genome Education Program  

SciTech Connect (OSTI)

The funds from the DOE Human Genome Program, for the project period 2/1/96 through 1/31/98, have provided major support for the curriculum development and field testing efforts for two high school level instructional units: Unit 1, ''Exploring Genetic Conditions: Genes, Culture and Choices''; and Unit 2, ''DNA Snapshots: Peaking at Your DNA''. In the original proposal, they requested DOE support for the partial salary and benefits of a Field Test Coordinator position to: (1) complete the field testing and revision of two high school curriculum units, and (2) initiate the education of teachers using these units. During the project period of this two-year DOE grant, a part-time Field-Test Coordinator was hired (Ms. Geraldine Horsma) and significant progress has been made in both of the original proposal objectives. Field testing for Unit 1 has occurred in over 12 schools (local and non-local sites with diverse student populations). Field testing for Unit 2 has occurred in over 15 schools (local and non-local sites) and will continue in 12-15 schools during the 96-97 school year. For both curricula, field-test sites and site teachers were selected for their interest in genetics education and in hands-on science education. Many of the site teachers had no previous experience with HGEP or the unit under development. Both of these first-year biology curriculum units, which contain genetics, biotechnology, societal, ethical and cultural issues related to HGP, are being implemented in many local and non-local schools (SF Bay Area, Southern California, Nebraska, Hawaii, and Texas) and in programs for teachers. These units will reach over 10,000 students in the SF Bay Area and continues to receive support from local corporate and private philanthropic organizations. Although HGEP unit development is nearing completion for both units, data is still being gathered and analyzed on unit effectiveness and student learning. The final field testing result from this analysis will contribute to the final revisions of each unit during the second-year of this grant.

Richard Myers; Lane Conn

2000-05-01T23:59:59.000Z

23

DOE human genome program contractor-grantee workshop VI  

SciTech Connect (OSTI)

Research is presented from the workshop on the Human Genome Project. Topics include sequencing, genetic mapping, informatics, ethical and legal issues, and infrastructure.

NONE

1997-10-01T23:59:59.000Z

24

Update on the Maize Genome Sequencing Project The Maize Genome Sequencing Project  

E-Print Network [OSTI]

Update on the Maize Genome Sequencing Project The Maize Genome Sequencing Project Vicki L. Chandler Genome Sequencing Project. The momentum for this endeavor has been building within the maize (Zea mays- sion. This Update reviews the project goals and the expected deliverables deriving from the two funded

Brendel, Volker

25

An integrated encyclopedia of DNA elements in the human genome  

E-Print Network [OSTI]

The human genome encodes the blueprint of life, but the function of the vast majority of its nearly three billion bases is unknown. The Encyclopedia of DNA Elements (ENCODE) project has systematically mapped regions of ...

Altshuler, Robert Charles

26

Human Genome: DOE Origins  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation ProposedUsingFun withconfinement plasmas inPortalAllBPA addressesHowHughHumanDecoding

27

Mapping our genes: The genome projects: How big, how fast  

SciTech Connect (OSTI)

For the past 2 years, scientific and technical journals in biology and medicine have extensively covered a debate about whether and how to determine the function and order of human genes on human chromosomes and when to determine the sequence of molecular building blocks that comprise DNA in those chromosomes. In 1987, these issues rose to become part of the public agenda. The debate involves science, technology, and politics. Congress is responsible for /open quotes/writing the rules/close quotes/ of what various federal agencies do and for funding their work. This report surveys the points made so far in the debate, focusing on those that most directly influence the policy options facing the US Congress. Congressional interest focused on how to assess the rationales for conducting human genome projects, how to fund human genome projects (at what level and through which mechanisms), how to coordinate the scientific and technical programs of the several federal agencies and private interests already supporting various genome projects, and how to strike a balance regarding the impact of genome projects on international scientific cooperation and international economic competition in biotechnology. OTA prepared this report with the assistance of several hundred experts throughout the world. 342 refs., 26 figs., 11 tabs.

none,

1988-04-01T23:59:59.000Z

28

A map of human genome variation from population-scale sequencing  

E-Print Network [OSTI]

The 1000 Genomes Project aims to provide a deep characterization of human genome sequence variation as a foundation for investigating the relationship between genotype and phenotype. Here we present results of the pilot ...

Lander, Eric S.

29

DOE Human Genome Program contractor-grantee workshop  

SciTech Connect (OSTI)

This volume contains the proceedings for the DOE Human Genome Program`s Contractor-Grantee Workshop V held in Sante Fe, New Mexico January 28, February 1, 1996. Presentations were divided into sessions entitled Sequencing; Mapping; Informatics; Ethical, Legal, and Social Issues; and Infrastructure. Reports of individual projects described herein are separately indexed and abstracted for the database.

NONE

1996-01-01T23:59:59.000Z

30

Stories of Discovery & Innovation: From Human Genome to Materials...  

Office of Science (SC) Website

Stories of Discovery & Innovation: From Human Genome to Materials "Genome" Energy Frontier Research Centers (EFRCs) EFRCs Home Centers Research Science Highlights News & Events...

31

Mapping the Human Genome: UC SANTA CRUZUC SANTA CRUZ  

E-Print Network [OSTI]

Mapping the Human Genome: UC SANTA CRUZUC SANTA CRUZ University of California Santa Cruz Foundation" of the human genome under the direction of UCSC computer science professor David Haussler (right). Story world. Unlocking the mysteries of the human genome and applying this new knowledge to improve our health

California at Santa Cruz, University of

32

Human Genome Research: Decoding DNA  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation ProposedUsingFun withconfinement plasmas inPortalAllBPA addressesHowHughHumanDecoding DNA

33

The Cancer Genome Atlas Pan-Cancer analysis project  

E-Print Network [OSTI]

The Cancer Genome Atlas (TCGA) Research Network has profiled and analyzed large numbers of human tumors to discover molecular aberrations at the DNA, RNA, protein and epigenetic levels. The resulting rich data provide a ...

Lander, Eric S.

34

Defining functional DNA elements in the human genome  

E-Print Network [OSTI]

With the completion of the human genome sequence, attention turned to identifying and annotating its functional DNA elements. As a complement to genetic and comparative genomics approaches, the Encyclopedia of DNA Elements ...

Kellis, Manolis

35

The Human Genome Initiative of the Department of Energy  

SciTech Connect (OSTI)

The structural characterization of genes and elucidation of their encoded functions have become a cornerstone of modern health research, biology and biotechnology. A genome program is an organized effort to locate and identify the functions of all the genes of an organism. Beginning with the DOE-sponsored, 1986 human genome workshop at Santa Fe, the value of broadly organized efforts supporting total genome characterization became a subject of intensive study. There is now national recognition that benefits will rapidly accrue from an effective scientific infrastructure for total genome research. In the US genome research is now receiving dedicated funds. Several other nations are implementing genome programs. Supportive infrastructure is being improved through both national and international cooperation. The Human Genome Initiative of the Department of Energy (DOE) is a focused program of Resource and Technology Development, with objectives of speeding and bringing economies to the national human genome effort. This report relates the origins and progress of the Initiative. 34 refs.

none,

1988-01-01T23:59:59.000Z

36

E-Print Network 3.0 - ancient human genome Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

human genome Page: << < 1 2 3 4 5 > >> 1 MOLECULAR BIOLOGY AND BIOCHEMISTRY Human Genomics Summary: MOLECULAR BIOLOGY AND BIOCHEMISTRY MBB 839-3 Human Genomics... of the human...

37

Joint Genome Institute (JGI) Projects at NERSC  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsruc DocumentationP-SeriesFlickrinformation forTechnologies |JenniferB. StorerJohnofJoint Genome

38

Human Genome Program Image Gallery (from genomics.energy.gov)  

DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

This collection contains approximately 240 images from the genome programs of DOE's Office of Science. The images are divided into galleries related to biofuels research, systems biology, and basic genomics. Each image has a title, a basic citation, and a credit or source. Most of the images are original graphics created by the Genome Management Information System (GMIS). GMIS images are recognizable by their credit line. Permission to use these graphics is not needed, but please credit the U.S. Department of Energy Genome Programs and provide the website http://genomics.energy.gov. Other images were provided by third parties and not created by the U.S. Department of Energy. Users must contact the person listed in the credit line before using those images. The high-resolution images can be downloaded.

39

Monochromosomal hybrids for the analysis of the human genome  

SciTech Connect (OSTI)

In this research project the authors proposed to develop rodent/human hybrid cell lines each containing a single different human chromosome. The human chromosomes will be marked with Ecogpt and stably maintained by selection in the hybrid cells. The experimental approach to produce the proposed cell lines involve the following: they will first transfer a cloned selectable marker, Ecogpt (an E. coli gene for xanthine-guanine phosphoribosyltransferase: XGPRT) to normal diploid human cells using a retroviral vector. The transferred gene will integrate at random into multiple sites in the recipient cell genome. Clonal cell lines from independent transgenotes will each carry the selectable marker integrated into a different site and perhaps a different chromosome. The chromosome carrying the selectable marker will then be transferred further to mouse cells by microcell fusion. In addition they also use directed integration of Ecogpt into the chromosome present in rodent cells, otherwise not marked with a selectable marker. This allows them to complete the bank of proposed cell line. The human chromosome, since it will be marked with a selectable marker, can be transferred to any other cell line of interest for complementation analysis. Clones of each cell line, containing varying size segments of the same chromosome produced by selection for the retention or loss of the selectable marker following x-irradiation or by metaphase chromosome transfer method will facilitate physical mapping and determination of gene order on a chromosome. 1 fig.

Athwal, R.S.

1990-01-01T23:59:59.000Z

40

Materials Project: A Materials Genome Approach  

DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

Technological innovation - faster computers, more efficient solar cells, more compact energy storage - is often enabled by materials advances. Yet, it takes an average of 18 years to move new materials discoveries from lab to market. This is largely because materials designers operate with very little information and must painstakingly tweak new materials in the lab. Computational materials science is now powerful enough that it can predict many properties of materials before those materials are ever synthesized in the lab. By scaling materials computations over supercomputing clusters, this project has computed some properties of over 80,000 materials and screened 25,000 of these for Li-ion batteries. The computations predicted several new battery materials which were made and tested in the lab and are now being patented. By computing properties of all known materials, the Materials Project aims to remove guesswork from materials design in a variety of applications. Experimental research can be targeted to the most promising compounds from computational data sets. Researchers will be able to data-mine scientific trends in materials properties. By providing materials researchers with the information they need to design better, the Materials Project aims to accelerate innovation in materials research.[copied from http://materialsproject.org/about] You will be asked to register to be granted free, full access.

Ceder, Gerbrand (MIT); Persson, Kristin (LBNL)

Note: This page contains sample records for the topic "human genome project" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


41

Closing gaps in the human genome using sequencing by synthesis  

E-Print Network [OSTI]

The most recent release of the finished human genome contains 260 euchromatic gaps (excluding chromosome Y). Recent work has helped explain a large number of these unresolved regions as 'structural' in nature. Another class ...

Arachchi, Harindra M.

42

The Genomes On Line Database (GOLD) in 2007: status of genomic and metagenomic projects and their associated metadata  

SciTech Connect (OSTI)

The Genomes On Line Database (GOLD) is a comprehensive resource of information for genome and metagenome projects world-wide. GOLD provides access to complete and ongoing projects and their associated metadata through pre-computed lists and a search page. The database currently incorporates information for more than 2900 sequencing projects, of which 639 have been completed and the data deposited in the public databases. GOLD is constantly expanding to provide metadata information related to the project and the organism and is compliant with the Minimum Information about a Genome Sequence (MIGS) specifications.

Fenner, Marsha W; Liolios, Konstantinos; Mavromatis, Konstantinos; Tavernarakis, Nektarios; Kyrpides, Nikos C.

2007-12-31T23:59:59.000Z

43

The Genomes On Line Database (GOLD) in 2009: status of genomic and metagenomic projects and their associated metadata  

SciTech Connect (OSTI)

The Genomes On Line Database (GOLD) is a comprehensive resource for centralized monitoring of genome and metagenome projects worldwide. Both complete and ongoing projects, along with their associated metadata, can be accessed in GOLD through precomputed tables and a search page. As of September 2009, GOLD contains information for more than 5800 sequencing projects, of which 1100 have been completed and their sequence data deposited in a public repository. GOLD continues to expand, moving toward the goal of providing the most comprehensive repository of metadata information related to the projects and their organisms/environments in accordance with the Minimum Information about a (Meta)Genome Sequence (MIGS/MIMS) specification.

Liolios, Konstantinos; Chen, Amy; Mavromatis, Konstantinos; Tavernarakis, Nektarios; Hugenholtz, Phil; Markowitz, Victor; Kyrpides, Nikos C.

2009-09-01T23:59:59.000Z

44

Sweeney, Abu and Winn Identifying Participants in the Personal Genome Project by Name Identifying Participants in the Personal Genome Project by Name  

E-Print Network [OSTI]

to make personal data sharing decisions, thereby depriving society of individual choice. To make smarterSweeney, Abu and Winn Identifying Participants in the Personal Genome Project by Name 1 Identifying Participants in the Personal Genome Project by Name Latanya Sweeney, Akua Abu, Julia Winn Harvard College

Chen, Yiling

45

Beyond The Human Genome: What's Next? (LBNL Summer Lecture Series)  

ScienceCinema (OSTI)

UC Berkeley's Daniel Rokhsar and his colleagues were instrumental in contributing the sequences for three of the human body's chromosomes in the effort to decipher the blueprint of life- the completion of the DNA sequencing of the human genome. Now he is turning to the structure and function of genes in other organisms, some of them no less important to the planet's future than the human map. Hear the latest in this lecture from Lawrence Berkeley National Laboratory.

Rokhsar, Daniel

2014-05-06T23:59:59.000Z

46

Defining Genome Project Standards in a New Era of Sequencing  

SciTech Connect (OSTI)

Patrick Chain of the DOE Joint Genome Institute gives a talk on behalf of the International Genome Sequencing Standards Consortium on the need for intermediate genome classifications between "draft" and "finished"

Chain, Patrick [DOE-JGI

2009-05-27T23:59:59.000Z

47

The Evolution of the Anopheles 16 Genomes Project  

E-Print Network [OSTI]

We report the imminent completion of a set of reference genome assemblies for 16 species of Anopheles mosquitoes. In addition to providing a generally useful resource for comparative genomic analyses, these genome sequences ...

Waterhouse, Robert

48

Genomic mosaicism in the human brain  

E-Print Network [OSTI]

Zlokovic BV (2008) The blood-brain barrier in health andmosaicism in the human brain ………………………………………. Chapter Threethe Alzheimer’s disease brain ………………………………. Chapter Five DNA

Westra, Jurjen Willem

2008-01-01T23:59:59.000Z

49

Genomes to life project quarterly report June 2004.  

SciTech Connect (OSTI)

This SAND report provides the technical progress through June 2004 of the Sandia-led project, ''Carbon Sequestration in Synechococcus Sp.: From Molecular Machines to Hierarchical Modeling'', funded by the DOE Office of Science Genomes to Life Program. Understanding, predicting, and perhaps manipulating carbon fixation in the oceans has long been a major focus of biological oceanography and has more recently been of interest to a broader audience of scientists and policy makers. It is clear that the oceanic sinks and sources of CO{sub 2} are important terms in the global environmental response to anthropogenic atmospheric inputs of CO{sub 2} and that oceanic microorganisms play a key role in this response. However, the relationship between this global phenomenon and the biochemical mechanisms of carbon fixation in these microorganisms is poorly understood. In this project, we will investigate the carbon sequestration behavior of Synechococcus Sp., an abundant marine cyanobacteria known to be important to environmental responses to carbon dioxide levels, through experimental and computational methods. This project is a combined experimental and computational effort with emphasis on developing and applying new computational tools and methods. Our experimental effort will provide the biology and data to drive the computational efforts and include significant investment in developing new experimental methods for uncovering protein partners, characterizing protein complexes, identifying new binding domains. We will also develop and apply new data measurement and statistical methods for analyzing microarray experiments. Computational tools will be essential to our efforts to discover and characterize the function of the molecular machines of Synechococcus. To this end, molecular simulation methods will be coupled with knowledge discovery from diverse biological data sets for high-throughput discovery and characterization of protein-protein complexes. In addition, we will develop a set of novel capabilities for inference of regulatory pathways in microbial genomes across multiple sources of information through the integration of computational and experimental technologies. These capabilities will be applied to Synechococcus regulatory pathways to characterize their interaction map and identify component proteins in these pathways. We will also investigate methods for combining experimental and computational results with visualization and natural language tools to accelerate discovery of regulatory pathways. The ultimate goal of this effort is develop and apply new experimental and computational methods needed to generate a new level of understanding of how the Synechococcus genome affects carbon fixation at the global scale. Anticipated experimental and computational methods will provide ever-increasing insight about the individual elements and steps in the carbon fixation process, however relating an organism's genome to its cellular response in the presence of varying environments will require systems biology approaches. Thus a primary goal for this effort is to integrate the genomic data generated from experiments and lower level simulations with data from the existing body of literature into a whole cell model. We plan to accomplish this by developing and applying a set of tools for capturing the carbon fixation behavior of complex of Synechococcus at different levels of resolution. Finally, the explosion of data being produced by high-throughput experiments requires data analysis and models which are more computationally complex, more heterogeneous, and require coupling to ever increasing amounts of experimentally obtained data in varying formats. These challenges are unprecedented in high performance scientific computing and necessitate the development of a companion computational infrastructure to support this effort.

Heffelfinger, Grant S.

2005-01-01T23:59:59.000Z

50

Human genome program report. Part 1, overview and progress  

SciTech Connect (OSTI)

This report contains Part 1 of a two-part report to reflect research and progress in the U.S. Department of Energy Human Genome Program from 1994 through 1996, with specified updates made just before publication. Part 1 consists of the program overview and report on progress.

NONE

1997-11-01T23:59:59.000Z

51

Human genome program report. Part 2, 1996 research abstracts  

SciTech Connect (OSTI)

This report contains Part 2 of a two-part report to reflect research and progress in the US Department of Energy Human Genome Program from 1994 through 1996, with specified updates made just before publication. Part 2 consists of 1996 research abstracts. Attention is focused on the following: sequencing; mapping; informatics; ethical, legal, and social issues; infrastructure; and small business innovation research.

NONE

1997-11-01T23:59:59.000Z

52

Unlocking the Secrets of the Genome  

E-Print Network [OSTI]

The primary objective of the Human Genome Project was to produce high-quality sequences not just for the human genome but also for those of the chief model organisms: Escherichia coli, yeast (Saccharomyces cerevisiae), ...

Celniker, Susan E.

53

Inverted Repeat Structure of the Human Genome: The X-Chromosome Contains a Preponderance of  

E-Print Network [OSTI]

Inverted Repeat Structure of the Human Genome: The X-Chromosome Contains a Preponderance of Large, Highly Homologous Inverted Repeats That Contain Testes Genes Peter E. Warburton,1,4 Joti Giordano,1 Fanny performed the first genome-wide analysis of the Inverted Repeat (IR) structure in the human genome, using

Warburton, Peter E.

54

Human genome sequencing with direct x-ray holographic imaging  

SciTech Connect (OSTI)

Direct holographic imaging of biological materials is widely applicable to the study of the structure, properties and action of genetic material. This particular application involves the sequencing of the human genome where prospective genomic imaging technology is composed of three subtechnologies, name an x-ray holographic camera, suitable chemistry and enzymology for the preparation of tagged DNA samples, and the illuminator in the form of an x-ray laser. We report appropriate x-ray camera, embodied by the instrument developed by MCR, is available and that suitable chemical and enzymatic procedures exist for the preparation of the necessary tagged DNA strands. Concerning the future development of the x-ray illuminator. We find that a practical small scale x-ray light source is indeed feasible. This outcome requires the use of unconventional physical processes in order to achieve the necessary power-compression in the amplifying medium. The understanding of these new physical mechanisms is developing rapidly. Importantly, although the x-ray source does not currently exist, the understanding of these new physical mechanisms is developing rapidly and the research has established the basic scaling laws that will determine the properties of the x-ray illuminator. When this x-ray source becomes available, an extremely rapid and cost effective instrument for 3-D imaging of biological materials can be applied to a wide range of biological structural assays, including the base-pair sequencing of the human genome and many questions regarding its higher levels of organization.

Rhodes, C.K.

1993-06-08T23:59:59.000Z

55

DOE/ER-0382 THE HUMAN GENOME INITIATIVE OF THE  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation Proposed Newcatalyst phases onOrganizationElectronic Reading2Q)382 THE HUMAN GENOME INITIATIVE

56

Optimized Multiplex PCR: Efficiently Closing a Whole-Genome Shotgun Sequencing Project  

E-Print Network [OSTI]

Optimized Multiplex PCR: Efficiently Closing a Whole-Genome Shotgun Sequencing Project Herve sequencing project. The method employs multiplex PCR and a novel pooling strategy to minimize the number of laboratory procedures required to se- quence the unknown DNA that falls in between con- tiguous sequences

57

Comparative Genomics of Transcriptional Control in the Human Malaria Parasite Plasmodium falciparum  

E-Print Network [OSTI]

Comparative Genomics of Transcriptional Control in the Human Malaria Parasite Plasmodium falciparum Richard M.R. Coulson,1,3 Neil Hall,2 and Christos A. Ouzounis1 1 Computational Genomics Group10 1SD, United Kingdom; 2 The Wellcome Trust Sanger Institute, The Wellcome Trust Genome Campus

Arnold, Jonathan

58

South African SKA Project Human Capital Development Programme  

E-Print Network [OSTI]

D and MSc Project List 1. Radio Astronomy Science 1.1 Radio Astronomy Science - PhD topics Project Title Project Description Qualifications and Skills Required Link to MeerKAT and/ or SKA Science Supervisor (andSouth African SKA Project Human Capital Development Programme Call for applications for 2014 Ph

Jarrett, Thomas H.

59

Fungal Genomics Presentation for BETO 2015 Project Peer Review  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:YearRound-UpHeatMulti-Dimensional ElectricalEnergyQualityAUGUSTPart 3 of3.2.103 Fungal Genomics

60

ANTH 376: GENOMICS & ANTHROPOLOGY 4 credit hours (satisfies an SC requirement)  

E-Print Network [OSTI]

1 ANTH 376: GENOMICS & ANTHROPOLOGY 4 credit hours (satisfies an SC variation, health and evolution. Extended Course Description The Human Genome Project and recent advances in genome sequencing techniques have made it possible

Note: This page contains sample records for the topic "human genome project" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


61

The Human Microbiome Project (HMP) and the Data Analysis and Coordination Center (DAAC) portal to the HMP (GSC8 Meeting)  

ScienceCinema (OSTI)

The Genomic Standards Consortium was formed in September 2005. It is an international, open-membership working body which promotes standardization in the description of genomes and the exchange and integration of genomic data. The 2009 meeting was an activity of a five-year funding "Research Coordination Network" from the National Science Foundation and was organized held at the DOE Joint Genome Institute with organizational support provided by the JGI and by the University of California - San Diego. George Weinstock from Washington University School of Medicine talks about the Human Microbiome Project (HMP) followed briefly by Jennifer Wortman from the University of Maryland School of Medicine on the Data Analysis and Coordination Center (DACC) portal to the HMP at the Genomic Standards Consortium's 8th meeting at the DOE JGI in Walnut Creek, Calif. on Sept. 9, 2009.

Weinstock, George [Washington University School of Medicine]; Wortman, Jennifer [University of Maryland School of Medicine

2011-04-29T23:59:59.000Z

62

DOE Human Genome Program: Contractor-Grantee Workshop IV, November 13--17, 1994, Santa Fe, New Mexico  

SciTech Connect (OSTI)

This volume contains the proceedings of the fourth Contractor-Grantee Workshop for the Department of Energy (DOE) Human Genome Program. Of the 204 abstracts in this book, some 200 describe the genome research of DOE-funded grantees and contractors located at the multidisciplinary centers at Lawrence Berkeley Laboratory, Lawrence Livermore National Laboratory, and Los Alamos National Laboratory; other DOE-supported laboratories; and more than 54 universities, research organizations, and companies in the United States and abroad. Included are 16 abstracts from ongoing projects in the Ethical, Legal, and Social Issues (ELSI) component, an area that continues to attract considerable attention from a wide variety of interested parties. Three abstracts summarize work in the new Microbial Genome Initiative launched this year by the Office of Health and Environmental Research (OHER) to provide genome sequence and mapping data on industrially important microorganisms and those that live under extreme conditions. Many of the projects will be discussed at plenary sessions held throughout the workshop, and all are represented in the poster sessions.

Not Available

1994-10-01T23:59:59.000Z

63

FCTO Projects and the Materials Genome Initiative | Department of Energy  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:Year in Review:Department of Energyand Review ofSafety Officer FAQS ReferenceFCTO Projects and

64

EA-0856: Construction and Operation of a Human Genome Laboratory at Lawrence Berkeley Laboratory Berkeley, California  

Broader source: Energy.gov [DOE]

This EA evaluates the environmental impacts of a proposal to construct and operate a new laboratory for consolidation of current and future activities of the Human Genome Center at the U.S....

65

MSc Human-Computer Interaction with Ergonomics MSc Project  

E-Print Network [OSTI]

MSc Human-Computer Interaction with Ergonomics MSc Project Web analytics and think aloud studies-Computer Interaction with Ergonomics) in the Faculty of Life Sciences, University College London, [2007]. NOTE

Blandford, Ann

66

The genomic complexity of primary human prostate cancer  

E-Print Network [OSTI]

Prostate cancer is the second most common cause of male cancer deaths in the United States. However, the full range of prostate cancer genomic alterations is incompletely characterized. Here we present the complete sequence ...

Carter, Scott Lambert

67

Project 3 Integrative Genomics (IG) Objective: To give a presentation of about 40-90 minutes duration at the end of the week covering the  

E-Print Network [OSTI]

Project 3 ­ Integrative Genomics (IG) Objective: To give a presentation of about 40-90 minutes duration at the end of the week covering the key aspects of the integrative genomics, which is the combined) "Integrative Genomics and Functional Explanation" downloadable from http://www.stats.ox.ac.uk/research/genome

Goldschmidt, Christina

68

JGI Fungal Genomics Program  

E-Print Network [OSTI]

JGI Fungal Genomics Program Igor V. Grigoriev 1 Lawrenceof California. JGI Fungal Genomics Program Contact: IgorJGI). Its key project, the Genomics Encyclopedia of Fungi,

Grigoriev, Igor V.

2012-01-01T23:59:59.000Z

69

Projecting human development and CO2 emissions  

E-Print Network [OSTI]

We estimate cumulative CO2 emissions during the period 2000 to 2050 from developed and developing countries based on the empirical relationship between CO2 per capita emissions (due to fossil fuel combustion and cement production) and corresponding HDI. In order to project per capita emissions of individual countries we make three assumptions which are detailed below. First, we use logistic regressions to fit and extrapolate the HDI on a country level as a function of time. This is mainly motivated by the fact that the HDI is bounded between 0 and 1 and that it decelerates as it approaches 1. Second, we employ for individual countries the correlations between CO2 per capita emissions and HDI in order to extrapolate their emissions. This is an ergodic assumption. Third, we let countries with incomplete data records evolve similarly as their close neighbors (in the emissions-HDI plane, see Fig. 1 in the main text) with complete time series of CO2 per capita emissions and HDI. Country-based emissions estimates a...

Costa, Luís; Kropp, Jürgen P

2012-01-01T23:59:59.000Z

70

Project funded under the Socio-economic Sciences and Humanities  

E-Print Network [OSTI]

1 Project funded under the Socio-economic Sciences and Humanities Can home ownership contribute real increases everywhere. What this translates into, in terms of an exact amount of housing wealth. Over the EU25 as a whole, housing equity is some 40 per cent higher than total GDP, the figure being

Birmingham, University of

71

Comparative Genomic Analysis of Human Fungal Pathogens Causing Paracoccidioidomycosis  

E-Print Network [OSTI]

Paracoccidioides is a fungal pathogen and the cause of paracoccidioidomycosis, a health-threatening human systemic mycosis endemic to Latin America. Infection by Paracoccidioides, a dimorphic fungus in the order Onygenales, ...

Holder, Jason W.

72

Population Genomics Objective: To give a presentation of about 40-90 minutes duration at the end of the week covering the key aspects  

E-Print Network [OSTI]

Population Genomics Objective: To give a presentation of about 40-90 minutes duration at the end of the week covering the key aspects of the population genomics of humans. This 1000 genomes project is devoted to the exciting project, where the genomes of a 1000 individuals are to be sequenced in the next

Goldschmidt, Christina

73

Mapping cis-Regulatory Domains in the Human Genome UsingMulti-Species Conservation of Synteny  

SciTech Connect (OSTI)

Our inability to associate distant regulatory elements with the genes that they regulate has largely precluded their examination for sequence alterations contributing to human disease. One major obstacle is the large genomic space surrounding targeted genes in which such elements could potentially reside. In order to delineate gene regulatory boundaries we used whole-genome human-mouse-chicken (HMC) and human-mouse-frog (HMF) multiple alignments to compile conserved blocks of synteny (CBS), under the hypothesis that these blocks have been kept intact throughout evolution at least in part by the requirement of regulatory elements to stay linked to the genes that they regulate. A total of 2,116 and 1,942 CBS>200 kb were assembled for HMC and HMF respectively, encompassing 1.53 and 0.86 Gb of human sequence. To support the existence of complex long-range regulatory domains within these CBS we analyzed the prevalence and distribution of chromosomal aberrations leading to position effects (disruption of a genes regulatory environment), observing a clear bias not only for mapping onto CBS but also for longer CBS size. Our results provide a genome wide data set characterizing the regulatory domains of genes and the conserved regulatory elements within them.

Ahituv, Nadav; Prabhakar, Shyam; Poulin, Francis; Rubin, EdwardM.; Couronne, Olivier

2005-06-13T23:59:59.000Z

74

Understanding Historical Human Migration Patterns and Interbreeding (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)  

SciTech Connect (OSTI)

Eske Willerslev from the University of Copenhagen on "Understanding Historical Human Migration Patterns and Interbreeding Using the Ancient Genomes of a Palaeo-Eskimo and an Aboriginal Australian" at the 7th Annual Genomics of Energy & Environment Meeting on March 21, 2012 in Walnut Creek, California.

Willerslev, Eske [University of Copenhagen] [University of Copenhagen

2012-03-21T23:59:59.000Z

75

Understanding Historical Human Migration Patterns and Interbreeding (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)  

ScienceCinema (OSTI)

Eske Willerslev from the University of Copenhagen on "Understanding Historical Human Migration Patterns and Interbreeding Using the Ancient Genomes of a Palaeo-Eskimo and an Aboriginal Australian" at the 7th Annual Genomics of Energy & Environment Meeting on March 21, 2012 in Walnut Creek, California.

Willerslev, Eske [University of Copenhagen

2013-01-15T23:59:59.000Z

76

Defining Genome Project Standards in a New Era of Sequencing (GSC8 Meeting)  

ScienceCinema (OSTI)

The Genomic Standards Consortium was formed in September 2005. It is an international, open-membership working body which promotes standardization in the description of genomes and the exchange and integration of genomic data. The 2009 meeting was an activity of a five-year funding "Research Coordination Network" from the National Science Foundation and was organized held at the DOE Joint Genome Institute with organizational support provided by the JGI and by the University of California - San Diego.

Chain, Patrick [DOE JGI

2011-04-28T23:59:59.000Z

77

Human genome sequencing with direct x-ray holographic imaging. Final report  

SciTech Connect (OSTI)

Direct holographic imaging of biological materials is widely applicable to the study of the structure, properties and action of genetic material. This particular application involves the sequencing of the human genome where prospective genomic imaging technology is composed of three subtechnologies, name an x-ray holographic camera, suitable chemistry and enzymology for the preparation of tagged DNA samples, and the illuminator in the form of an x-ray laser. We report appropriate x-ray camera, embodied by the instrument developed by MCR, is available and that suitable chemical and enzymatic procedures exist for the preparation of the necessary tagged DNA strands. Concerning the future development of the x-ray illuminator. We find that a practical small scale x-ray light source is indeed feasible. This outcome requires the use of unconventional physical processes in order to achieve the necessary power-compression in the amplifying medium. The understanding of these new physical mechanisms is developing rapidly. Importantly, although the x-ray source does not currently exist, the understanding of these new physical mechanisms is developing rapidly and the research has established the basic scaling laws that will determine the properties of the x-ray illuminator. When this x-ray source becomes available, an extremely rapid and cost effective instrument for 3-D imaging of biological materials can be applied to a wide range of biological structural assays, including the base-pair sequencing of the human genome and many questions regarding its higher levels of organization.

Rhodes, C.K.

1993-06-08T23:59:59.000Z

78

Personal Genomics, Personalized Medicine,  

E-Print Network [OSTI]

Personal Genomics, Personalized Medicine, & YOU Carrie Iwema, PhD, MLS 21st May 2012 AAAS/Science Translational Medicine panel discussion; MLA 2012 #12;Timeline: Human Genome Sequence HSLS, U.Pitt 1995 2014 2000 2003 2007 2007 2010 Human Genome Draft Sequence Complete Human Reference Genome Individual Human

Napp, Nils

79

COORDINATING HUMAN AND MATERIAL RESOURCES Construction project management is the art of directing and coordinating human and material  

E-Print Network [OSTI]

COORDINATING HUMAN AND MATERIAL RESOURCES Construction project management is the art of directing and coordinating human and material resources throughout the life of a project by using modern management. Today's construction engineers and managers are faced with unprecedented challenges in planning

Simaan, Nabil

80

Genomic analysis of mouse tumorigenesis  

E-Print Network [OSTI]

The availability of the human and mouse genome sequences has spurred a growing interest in analyzing mouse models of human cancer using genomic techniques. Comparative genomic studies on mouse and human tumors can be ...

Tam, Mandy Chi-Mun

2006-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "human genome project" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


81

Genome Improvement at JGI-HAGSC  

SciTech Connect (OSTI)

Since the completion of the sequencing of the human genome, the JGI has rapidly expanded its scientific goals in several DOE mission-relevant areas. At the JGI-HAGSC, we have kept pace with this rapid expansion of projects with our focus on assessing, assembling, improving and finishing eukaryotic whole genome shotgun (WGS) projects for which the shotgun sequence is generated at the Production Genomic Facility (JGI-PGF). We follow this by combining the draft WGS with genomic resources generated at JGI-HAGSC or in collaborator laboratories (including BAC end sequences, genetic maps and FLcDNA sequences) to produce an improved draft sequence. For eukaryotic genomes important to the DOE mission, we then add further information from directed experiments to produce reference genomic sequences that are publicly available for any scientific researcher. Also, we have continued our program for producing BAC-based finished sequence, both for adding information to JGI genome projects and for small BAC-based sequencing projects proposed through any of the JGI sequencing programs. We have now built our computational expertise in WGS assembly and analysis and have moved eukaryotic genome assembly from the JGI-PGF to JGI-HAGSC. We have concentrated our assembly development work on large plant genomes and complex fungal and algal genomes.

Grimwood, Jane: Schmutz, Jeremy, J.: Myers, Richard, M.

2012-03-03T23:59:59.000Z

82

Large-scale discovery and validation of functional elements in the human genome  

E-Print Network [OSTI]

A report on the genomics workshop 'Identification of Functional Elements in Mammalian Genomes', Cold Spring Harbor, New York, 11-13 November 2004.

Kellis, Manolis

83

Genome-Wide siRNA-Based Functional Genomics of Pigmentation Identifies Novel Genes and Pathways That Impact Melanogenesis in Human Cells  

E-Print Network [OSTI]

siRNA-Based Functional Genomics of Pigmentation Identifiespoorly understood. Functional genomics based on RNA-mediatedof RNAi-based functional genomics to identify novel genes,

2008-01-01T23:59:59.000Z

84

Functional genomics studies of human brain development and implications for autism spectrum disorder  

E-Print Network [OSTI]

into the genetic and molecular basis of higher cognition. However, the underlying pathophysiology of autism spectrum disorders has long been a mystery. Various hypothesis ranging from psychosocial abnormalities to environmental insults have been purported... that the genomic architecture of ASD is incredibly heterogeneous and complex, necessitating a functional integration in order to decipher common molecular mechanisms underlying ASD. Genomic Architecture of ASD The identification of genomic loci and individual...

Ziats, Mark

2014-07-01T23:59:59.000Z

85

Environmental assessment for construction and operation of a Human Genome Laboratory at Lawrence Berkeley Laboratory, Berkeley, California  

SciTech Connect (OSTI)

Lawrence Berkeley Laboratory (LBL) proposes to construct and operate a new laboratory for consolidation of current and future activities of the Human Genome Center (HGC). This document addresses the potential direct, indirect, and cumulative environmental and human-health effects from the proposed facility construction and operation. This document was prepared in accordance the National Environmental Policy Act of 1969 (United States Codes 42 USC 4321-4347) (NEPA) and the US Department of Energy`s (DOE) Final Rule for NEPA Implementing Procedures [Code of Federal Regulations 10CFR 1021].

NONE

1994-12-01T23:59:59.000Z

86

Draft Genome Sequences of Six Enterohepatic Helicobacter Species Isolated from Humans and One from Rhesus Macaques  

E-Print Network [OSTI]

Draft genome sequences of seven enterohepatic Helicobacter species, H. bilis, H. canadensis, H. canis, H. cinaedi, H. winghamensis, H. pullorum, and H. macacae, are presented. These isolates were obtained from clinical ...

Shen, Zeli

87

New families of human regulatory RNA structures identified by comparative analysis of vertebrate genomes  

E-Print Network [OSTI]

Regulatory RNA structures are often members of families with multiple paralogous instances across the genome. Family members share functional and structural properties, which allow them to be studied as a whole, facilitating ...

Kellis, Manolis

88

Genomics of emerging infectious disease: A PLoS collection.  

E-Print Network [OSTI]

Origins and evolutionary genomics of the 2009 swine-originan Infectious Diseases Genomics Project predict and preventRavel J (2009) The role of genomics in the identification,

Eisen, Jonathan A; MacCallum, Catriona J

2009-01-01T23:59:59.000Z

89

Habitat for Humanity: La Grange, Georgia, 2003 Jimmy Carter Work Project  

SciTech Connect (OSTI)

The Troup-Chambers Habitat for Humanity built a Habitat house to ENERGY STAR standards in LaGrange, Georgia, in 2003. The project was so successfully that all Troup-Chambers houses will now be built to ENERGY STAR standards.

Not Available

2005-06-01T23:59:59.000Z

90

Ohnologs in the human genome are dosage balanced and frequently associated with disease  

E-Print Network [OSTI]

. In particular, Down Syndrome (DS) caused by trisomy 21 is widely assumed to be caused by dosage effects, and 75 duplication | copy number variation | Down Syndrome | trisomy 21 Early in the vertebrate lineage the genome% of previously reported candidate genes for this syndrome are ohnologs that experienced no other copy number

McLysaght, Aoife

91

Department Human Resources Bulletin, #027, FY06, dated August 1,2006 DOC Demonstration Project Operating Procedures  

E-Print Network [OSTI]

Project Operating Procedures Purpose This issuance provides NOAA managers with pay setting flexibilitywhen Demonstration Project OperatingProcedures. . . . , . . Background On August 1,2006, the Department issued Human setting pay for Presidential Management Fellows (PMF) who are covered by the DOC Demonstration Project

92

Institute for Plant Genomics and Biotechnology GENOMICS AND BIOTECHNOLOGY  

E-Print Network [OSTI]

Institute for Plant Genomics and Biotechnology GENOMICS AND BIOTECHNOLOGY A multidisciplinary organization, the Institute for Plant Genomics and Biotechnology is a composed of faculty members representing projects at the Institute for Plant Genomics and Biotechnology include the development of transgenic plants

93

Gray, W. D. (2003). Cognitive factors in homeland defense: The role of human factors in the novel intelligence from massive data (NIMD) project, Human Factors and Ergonomics Society (pp. 1017-1018). Santa Monica, CA: Human  

E-Print Network [OSTI]

intelligence from massive data (NIMD) project, Human Factors and Ergonomics Society (pp. 1017-1018). Santa Monica, CA: Human Factors and Ergonomics Society. COGNITIVE FACTORS IN HOMELAND DEFENSE: THE ROLE

Gray, Wayne

94

JGI Fungal Genomics Program  

SciTech Connect (OSTI)

Genomes of energy and environment fungi are in focus of the Fungal Genomic Program at the US Department of Energy Joint Genome Institute (JGI). Its key project, the Genomics Encyclopedia of Fungi, targets fungi related to plant health (symbionts, pathogens, and biocontrol agents) and biorefinery processes (cellulose degradation, sugar fermentation, industrial hosts), and explores fungal diversity by means of genome sequencing and analysis. Over 50 fungal genomes have been sequenced by JGI to date and released through MycoCosm (www.jgi.doe.gov/fungi), a fungal web-portal, which integrates sequence and functional data with genome analysis tools for user community. Sequence analysis supported by functional genomics leads to developing parts list for complex systems ranging from ecosystems of biofuel crops to biorefineries. Recent examples of such 'parts' suggested by comparative genomics and functional analysis in these areas are presented here

Grigoriev, Igor V.

2011-03-14T23:59:59.000Z

95

Genomic Encyclopedia of Fungi  

SciTech Connect (OSTI)

Genomes of fungi relevant to energy and environment are in focus of the Fungal Genomic Program at the US Department of Energy Joint Genome Institute (JGI). Its key project, the Genomics Encyclopedia of Fungi, targets fungi related to plant health (symbionts, pathogens, and biocontrol agents) and biorefinery processes (cellulose degradation, sugar fermentation, industrial hosts), and explores fungal diversity by means of genome sequencing and analysis. Over 150 fungal genomes have been sequenced by JGI to date and released through MycoCosm (www.jgi.doe.gov/fungi), a fungal web-portal, which integrates sequence and functional data with genome analysis tools for user community. Sequence analysis supported by functional genomics leads to developing parts list for complex systems ranging from ecosystems of biofuel crops to biorefineries. Recent examples of such parts suggested by comparative genomics and functional analysis in these areas are presented here.

Grigoriev, Igor

2012-08-10T23:59:59.000Z

96

10. international mouse genome conference  

SciTech Connect (OSTI)

Ten years after hosting the First International Mammalian Genome Conference in Paris in 1986, Dr. Jean-Louis Guenet presided over the Tenth Conference at the Pasteur Institute, October 7--10, 1996. The 1986 conference was a satellite to the Human Gene Mapping Workshop and had approximately 50 attendees. The 1996 meeting was attended by 300 scientists from around the world. In the interim, the number of mapped loci in the mouse increased from 1,000 to over 20,000. This report contains a listing of the program and its participants, and two articles that review the meeting and the role of the laboratory mouse in the Human Genome project. More than 200 papers were presented at the conference covering the following topics: International mouse chromosome committee meetings; Mutant generation and identification; Physical and genetic maps; New technology and resources; Chromatin structure and gene regulation; Rate and hamster genetic maps; Informatics and databases; and Quantitative trait analysis.

Meisler, M.H.

1996-12-31T23:59:59.000Z

97

Chromosome region-specific libraries for human genome analysis. Final progress report, 1 March 1991--28 February 1994  

SciTech Connect (OSTI)

The objectives of this grant proposal include (1) development of a chromosome microdissection and PCR-mediated microcloning technology, (2) application of this microtechnology to the construction of region-specific libraries for human genome analysis. During this grant period, the authors have successfully developed this microtechnology and have applied it to the construction of microdissection libraries for the following chromosome regions: a whole chromosome 21 (21E), 2 region-specific libraries for the long arm of chromosome 2, 2q35-q37 (2Q1) and 2q33-q35 (2Q2), and 4 region-specific libraries for the entire short arm of chromosome 2, 2p23-p25 (2P1), 2p21-p23 (2P2), 2p14-p16 (wP3) and 2p11-p13 (2P4). In addition, 20--40 unique sequence microclones have been isolated and characterized for genomic studies. These region-specific libraries and the single-copy microclones from the library have been used as valuable resources for (1) isolating microsatellite probes in linkage analysis to further refine the disease locus; (2) isolating corresponding clones with large inserts, e.g. YAC, BAC, P1, cosmid and phage, to facilitate construction of contigs for high resolution physical mapping; and (3) isolating region-specific cDNA clones for use as candidate genes. These libraries are being deposited in the American Type Culture Collection (ATCC) for general distribution.

Kao, F.T.

1994-04-01T23:59:59.000Z

98

Genome Science and Personalized Cancer Treatment  

ScienceCinema (OSTI)

August 4, 2009 Berkeley Lab lecture: Results from the Human Genome Project are enabling scientists to understand how individual cancers form and progress. This information, when combined with newly developed drugs, can optimize the treatment of individual cancers. Joe Gray, director of Berkeley Labs Life Sciences Division and Associate Laboratory Director for Life and Environmental Sciences, will focus on this approach, its promise, and its current roadblocks ? particularly with regard to breast cancer.

Joe Gray

2010-01-08T23:59:59.000Z

99

Mammalian comparative genomics and epigenomics  

E-Print Network [OSTI]

The human genome sequence can be thought of as an instruction manual for our species, written and rewritten over more than a billion of years of evolution. Taking a complete inventory of our genome, dissecting its genes ...

Mikkelsen, Tarjei Sigurd, 1978-

2009-01-01T23:59:59.000Z

100

Computational genomics on the grid.  

E-Print Network [OSTI]

??The post-genomic era is characterized by large amount of data available from sequencing projects. The large size of biological datasets, inherent complexity of biological problems… (more)

Chen, Chunxi.

2008-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "human genome project" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


101

Isotope-based medical research in the post genome era: Gene-orchestrated life functions in medicine seen and affected by isotopes. Workshop report  

SciTech Connect (OSTI)

The US Department of Energy (DOE) and the National Institutes of Health (NIH) conducted a workshop on Isotope-Based Medical Research in the Post Genome Era at NIH, Bethesda, Maryland, November 12--14, 1997. The workshop aimed at identifying the role of stable and radioisotopes for advanced diagnosis and therapy of a wide range of illnesses using the new information that comes from the human genome program. In this sense, the agenda addressed the challenge of functional genomics in humans. The workshop addressed: functional genomics in clinical medicine; new diagnostic potentials; new therapy potentials; challenge to tracer- and effector-pharmaceutical chemistry; and project plans for joint ventures.

Feinendegen, L.E.

1997-12-31T23:59:59.000Z

102

Evolutionary genomics of divergence and adaptation within the model fungi Neurospora crassa and Neurospora tetrasperma  

E-Print Network [OSTI]

Taylor JW. 2011. Population genomics and local adaptation inpromise of population genomics: from genotyping to genomeera. Annual Review of Genomics and Human Genetics 11:265-89.

Ellison, Christopher

2011-01-01T23:59:59.000Z

103

Clustering and Registration of Functional Data with Applications in Time Course Genomics Data  

E-Print Network [OSTI]

of Clustering Methods for Time Course Genomics Data . .Methods for Time Course Genomics Data. To be submitted S.human subjects. BMC Genomics, 13, 2012. 636. Kongming Wang

Zhang, Yafeng

2014-01-01T23:59:59.000Z

104

Extreme Genomics By Scouring the Genomes of 50 HIV-Resistant People, Study  

E-Print Network [OSTI]

Extreme Genomics By Scouring the Genomes of 50 HIV-Resistant People, Study Takes Aim at Rare Gene Genome Variation, and his colleagues think that the complete genome sequences of those fortunate few against the viral strain that usually infects humans. That's because the CCR5 protein is Extreme Genomics

Dolbow, John

105

Report on {open_quotes}inspection of human subject research in intelligence and intelligence-related projects{close_quotes}  

SciTech Connect (OSTI)

Executive Order 12333, {open_quotes}United States Intelligence Activities,{close_quotes} (1) designates the Department`s intelligence element as a member of the Intelligence Community, and (2) states that no agency within the Intelligence community shall sponsor, contract for or conduct research on human subjects except in accordance with guidelines issued by the Department of Health and Human Services. The Federal policy for the Protection of Human Subjects, which was based on Department of Health and Human Services regulations, was promulgated in Title 10 Code of Federal Regulations Part 745 by the Department of Energy. The purpose of this inspection was to review the internal control procedures used by the Office of Nonproliferation and National Security to manage selected intelligence and intelligence-related projects that involve human subject research.

NONE

1996-01-16T23:59:59.000Z

106

A clamp ligation method for point mutational spectrometry : marked increase in scanning range for the human genome  

E-Print Network [OSTI]

The study of human mutagenesis requires methods of measuring somatic mutations in normal human tissues and inherited mutations in human populations. Such methods should permit measurement of rare mutations in the presence ...

Kim, Andrea Seungsun, 1971-

2002-01-01T23:59:59.000Z

107

The common ground of genomics and systems biology  

E-Print Network [OSTI]

8/S2. Authors’ details Genomics of Gene Expression Lab,systems biology. Annu Rev. Genomics Hum. Genet 2001, 2:343-projection strategies. Genomics 2008, 92(6):373-83. 31.

Conesa, Ana; Mortazavi, Ali

2014-01-01T23:59:59.000Z

108

Aspergillus Niger Genomics: Past, Present and into the Future  

SciTech Connect (OSTI)

Aspergillus niger is a filamentous ascomycete fungus that is ubiquitous in the environment and has been implicated in opportunistic infections of humans. In addition to its role as an opportunistic human pathogen, A. niger is economically important as a fermentation organism used for the production of citric acid. Industrial citric acid production by A. niger represents one of the most efficient, highest yield bioprocesses in use currently by industry. The genome size of A. niger is estimated to be between 35.5 and 38.5 megabases (Mb) divided among eight chromosomes/linkage groups that vary in size from 3.5 - 6.6 Mb. Currently, there are three independent A. niger genome projects, an indication of the economic importance of this organism. The rich amount of data resulting from these multiple A. niger genome sequences will be used for basic and applied research programs applicable to fermentation process development, morphology and pathogenicity.

Baker, Scott E.

2006-09-01T23:59:59.000Z

109

Fungal Genomics Program  

SciTech Connect (OSTI)

The JGI Fungal Genomics Program aims to scale up sequencing and analysis of fungal genomes to explore the diversity of fungi important for energy and the environment, and to promote functional studies on a system level. Combining new sequencing technologies and comparative genomics tools, JGI is now leading the world in fungal genome sequencing and analysis. Over 120 sequenced fungal genomes with analytical tools are available via MycoCosm (www.jgi.doe.gov/fungi), a web-portal for fungal biologists. Our model of interacting with user communities, unique among other sequencing centers, helps organize these communities, improves genome annotation and analysis work, and facilitates new larger-scale genomic projects. This resulted in 20 high-profile papers published in 2011 alone and contributing to the Genomics Encyclopedia of Fungi, which targets fungi related to plant health (symbionts, pathogens, and biocontrol agents) and biorefinery processes (cellulose degradation, sugar fermentation, industrial hosts). Our next grand challenges include larger scale exploration of fungal diversity (1000 fungal genomes), developing molecular tools for DOE-relevant model organisms, and analysis of complex systems and metagenomes.

Grigoriev, Igor

2012-03-12T23:59:59.000Z

110

Population genomics20-02-2009 Antnio Rodrigues; Bruno Santos / 59 Population Genomics  

E-Print Network [OSTI]

Population genomics20-02-2009 António Rodrigues; Bruno Santos / 59 Population Genomics 1 António Rodrigues (PDBC 2008) Bruno Santos (PDBC 2008) #12;Population genomics20-02-2009 António Rodrigues; Bruno Santos / 59 Contents 2 2 1000 genome project 1 Motivation and Introduction New generation sequencing

Goldschmidt, Christina

111

Hybrid Human Powered Vehicle (Phase 3) The Zero EMission (ZEM) Vehicle Project  

E-Print Network [OSTI]

The Construction of ZEM Car ­ a hybrid human/electric/solar powered vehicle (P-2) (2007-2008) Principal) Hybrid human pedaling/ electric powered vehicle- Designed and constructed P-1 prototype Sponsor: SJSU) Hybrid human pedaling/ Electric/solar powered vehicle (HPV-ZEM)-Designed P-2 Sponsor: SJSU-COE 16 ME + 3

Su, Xiao

112

The Human Genome Project and other biological research efforts are creating an avalanche of new data about the chemical makeu  

Office of Scientific and Technical Information (OSTI)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary)morphinanInformation InInformation In closing, an National Carbon Capture Center at theDark MatterProteinShop

113

Genome Science and Personalized Cancer Treatment (LBNL Summer Lecture Series)  

ScienceCinema (OSTI)

Summer Lecture Series 2009: Results from the Human Genome Project are enabling scientists to understand how individual cancers form and progress. This information, when combined with newly developed drugs, can optimize the treatment of individual cancers. Joe Gray, director of Berkeley Labs Life Sciences Division and Associate Laboratory Director for Life and Environmental Sciences, will focus on this approach, its promise, and its current roadblocks ? particularly with regard to breast cancer.

Gray, Joe

2011-04-28T23:59:59.000Z

114

GOLD: The Genomes Online Database  

DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

Since its inception in 1997, GOLD has continuously monitored genome sequencing projects worldwide and has provided the community with a unique centralized resource that integrates diverse information related to Archaea, Bacteria, Eukaryotic and more recently Metagenomic sequencing projects. As of September 2007, GOLD recorded 639 completed genome projects. These projects have their complete sequence deposited into the public archival sequence databases such as GenBank EMBL,and DDBJ. From the total of 639 complete and published genome projects as of 9/2007, 527 were bacterial, 47 were archaeal and 65 were eukaryotic. In addition to the complete projects, there were 2158 ongoing sequencing projects. 1328 of those were bacterial, 59 archaeal and 771 eukaryotic projects. Two types of metadata are provided by GOLD: (i) project metadata and (ii) organism/environment metadata. GOLD CARD pages for every project are available from the link of every GOLD_STAMP ID. The information in every one of these pages is organized into three tables: (a) Organism information, (b) Genome project information and (c) External links. [The Genomes On Line Database (GOLD) in 2007: Status of genomic and metagenomic projects and their associated metadata, Konstantinos Liolios, Konstantinos Mavromatis, Nektarios Tavernarakis and Nikos C. Kyrpides, Nucleic Acids Research Advance Access published online on November 2, 2007, Nucleic Acids Research, doi:10.1093/nar/gkm884]

The basic tables in the GOLD database that can be browsed or searched include the following information:

  • Gold Stamp ID
  • Organism name
  • Domain
  • Links to information sources
  • Size and link to a map, when available
  • Chromosome number, Plas number, and GC content
  • A link for downloading the actual genome data
  • Institution that did the sequencing
  • Funding source
  • Database where information resides
  • Publication status and information

(Specialized Interface)

Kyrpides, Nikos; Liolios, Dinos; Chen, Amy; Tavernarakis, Nektarios; Hugenholtz, Philip; Markowitz, Victor; Bernal, Alex

115

Culminating applications of human factors to the academic affairs web team projects.  

E-Print Network [OSTI]

??The demand for Human Factors specialists in the private sector has grown significantly in the past decade. One reason for this demand is attributed to… (more)

Atachagua, Juan Antonio

2015-01-01T23:59:59.000Z

116

Considerations Related To Human Intrusion In The Context Of Disposal Of Radioactive Waste-The IAEA HIDRA Project  

SciTech Connect (OSTI)

The principal approaches for management of radioactive waste are commonly termed ‘delay and decay’, ‘concentrate and contain’ and ‘dilute and disperse’. Containing the waste and isolating it from the human environment, by burying it, is considered to increase safety and is generally accepted as the preferred approach for managing radioactive waste. However, this approach results in concentrated sources of radioactive waste contained in one location, which can pose hazards should the facility be disrupted by human action in the future. The International Commission on Radiological Protection (ICRP), International Atomic Energy Agency (IAEA), and Organization for Economic Cooperation and Development/Nuclear Energy Agency (OECD/NEA) agree that some form of inadvertent human intrusion (HI) needs to be considered to address the potential consequences in the case of loss of institutional control and loss of memory of the disposal facility. Requirements are reflected in national regulations governing radioactive waste disposal. However, in practice, these requirements are often different from country to country, which is then reflected in the actual implementation of HI as part of a safety case. The IAEA project on HI in the context of Disposal of RadioActive waste (HIDRA) has been started to identify potential areas for improved consistency in consideration of HI. The expected outcome is to provide recommendations on how to address human actions in the safety case in the future, and how the safety case may be used to demonstrate robustness and optimize siting, design and waste acceptance criteria within the context of a safety case.

Seitz, Roger; Kumano, Yumiko; Bailey, Lucy; Markley, Chris; Andersson, Eva; Beuth, Thomas

2014-01-09T23:59:59.000Z

117

Humanities and Social Relevance for Chemistry and Chemical Engineering Students: The Leonardo Project  

E-Print Network [OSTI]

Humanities and Social Relevance for Chemistry and Chemical Engineering Students: The Leonardo chemistry and chemical-engineering education. Its goal is to prepare educational materials on the interface between chemical technology and society for use by chemical-engineering or chemistry professors

Doudna, Jennifer A.

118

Why Human Disease-Associated Residues Appear as the Wild-Type in Other Species: Genome-Scale Structural  

E-Print Network [OSTI]

: Jeffrey Thorne Abstract Many human-disease associated amino acid residues (DARs) appear as the wild in these other species that alleviate the deleterious effects of the DARs. The general validity the compensation hypothesis by assembling and analyzing 1,077 DARs located in 177 proteins of known crystal

Zhang, Jianzhi

119

Genomics and Systems Biology  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Genomics and Systems Biology Genomics and Systems Biology Los Alamos scientists perform research in functional genomics and structural genomics, and applications for such work...

120

Molluscan Evolutionary Genomics  

E-Print Network [OSTI]

59179 Molluscan Evolutionary Genomics W. Brian Simison andBoore Molluscan Evolutionary Genomics W. Brian Simison andL. Boore Evolutionary Genomics Department, DOE Joint Genome

Simison, W. Brian

2010-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "human genome project" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


121

E-Print Network 3.0 - array-comparative genomic hybridization...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

for understanding disease aetiology and preventing its development. FUNCTIONAL GENOMICS Analysis of sequence... % of the human genome. Most conserved ... Source: Feschotte,...

122

Algorithms for genomics and genetics : compression-accelerated search and admixture analysis .  

E-Print Network [OSTI]

??Rapid advances in next-generation sequencing technologies are revolutionizing genomics, with data sets at the scale of thousands of human genomes fast becoming the norm. These… (more)

Loh, Po-Ru

2013-01-01T23:59:59.000Z

123

Genome Engineering  

SciTech Connect (OSTI)

Dan Voytas, University of Minnesota, at the 9th Annual Genomics of Energy & Environment Meeting on March 20, 2014 in Walnut Creek, Calif

Voytas, Dan [University of Minnesota

2014-03-20T23:59:59.000Z

124

DOE Humanities Projects Announced | U.S. DOE Office of Science (SC)  

Office of Science (SC) Website

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear SecurityTensile Strain Switched5 Industrial CarbonArticlesHumanJune 2008Contractor Humanof Science (SC)DOE

125

Screening Assessment of Potential Human-Health Risk from Future Natural-Gas Drilling Near Project Rulison in Western Colorado  

SciTech Connect (OSTI)

The Project Rulison underground nuclear test was conducted in 1969 at a depth of 8,400 ft in the Williams Fork Formation of the Piceance Basin, west-central Colorado (Figure 1). The U.S. Department of Energy Office of Legacy Management (LM) is the steward of the site. Their management is guided by data collected from past site investigations and current monitoring, and by the results of calculations of expected behavior of contaminants remaining in the deep subsurface. The purpose of this screening risk assessment is to evaluate possible health risks from current and future exposure to Rulison contaminants so the information can be factored into LM's stewardship decisions. For example, these risk assessment results can inform decisions regarding institutional controls at the site and appropriate monitoring of nearby natural-gas extraction activities. Specifically, the screening risk analysis can provide guidance for setting appropriate action levels for contaminant monitoring to ensure protection of human health.

Daniels Jeffrey I.,Chapman Jenny B.

2012-01-01T23:59:59.000Z

126

A Taste of Algal Genomes from the Joint Genome Institute  

SciTech Connect (OSTI)

Algae play profound roles in aquatic food chains and the carbon cycle, can impose health and economic costs through toxic blooms, provide models for the study of symbiosis, photosynthesis, and eukaryotic evolution, and are candidate sources for bio-fuels; all of these research areas are part of the mission of DOE's Joint Genome Institute (JGI). To date JGI has sequenced, assembled, annotated, and released to the public the genomes of 18 species and strains of algae, sampling almost all of the major clades of photosynthetic eukaryotes. With more algal genomes currently undergoing analysis, JGI continues its commitment to driving forward basic and applied algal science. Among these ongoing projects are the pan-genome of the dominant coccolithophore Emiliania huxleyi, the interrelationships between the 4 genomes in the nucleomorph-containing Bigelowiella natans and Guillardia theta, and the search for symbiosis genes of lichens.

Kuo, Alan; Grigoriev, Igor

2012-06-17T23:59:59.000Z

127

Evolution and comparative genomics of subcellular specializations: EST sequencing of Torpedo electric organ  

E-Print Network [OSTI]

Evolution and comparative genomics of subcellular specializations: EST sequencing of Torpedo discovery Open reading frame (ORF) Uncharacterized open reading frames (ORFs) in human genomic sequence Elsevier B.V. All rights reserved. 1. Introduction The availability of complete genomic sequences

Vertes, Akos

128

12 IEEE TRANSACTIONS ON NANOTECHNOLOGY, VOL. 1, NO. 1, MARCH 2002 Scanning the Controls: Genomics and  

E-Print Network [OSTI]

12 IEEE TRANSACTIONS ON NANOTECHNOLOGY, VOL. 1, NO. 1, MARCH 2002 Scanning the Controls: Genomics and topological complexity is the complexity of the genome itself, consisting of about one billion basepairs. The Human Genome Proj

129

Chapter 27 -- Breast Cancer Genomics, Section VI, Pathology and Biological Markers of Invasive Breast Cancer  

E-Print Network [OSTI]

2007;318:1108–1113.   8.  Cancer Genome Atlas Network.  somatic mutation in human cancer genomes.   Nature 2007;446:153–158.   11.  Katoh M.  Cancer genomics and genetics of 

Spellman, Paul T.

2011-01-01T23:59:59.000Z

130

The mechanism and function of pervasive noncoding transcription in the mammalian genome  

E-Print Network [OSTI]

The vast majority of the mammalian genome does not encode proteins. Only 2% of the genome is exonic, yet recent deep survey of human transcripitome suggested that 75% of the genome is transcribed, including half of the ...

Wu, Xuebing, Ph. D. Massachusetts Institute of Technology

2014-01-01T23:59:59.000Z

131

DOE Joint Genome Institute 2008 Progress Report  

SciTech Connect (OSTI)

While initially a virtual institute, the driving force behind the creation of the DOE Joint Genome Institute in Walnut Creek, California in the Fall of 1999 was the Department of Energy's commitment to sequencing the human genome. With the publication in 2004 of a trio of manuscripts describing the finished 'DOE Human Chromosomes', the Institute successfully completed its human genome mission. In the time between the creation of the Department of Energy Joint Genome Institute (DOE JGI) and completion of the Human Genome Project, sequencing and its role in biology spread to fields extending far beyond what could be imagined when the Human Genome Project first began. Accordingly, the targets of the DOE JGI's sequencing activities changed, moving from a single human genome to the genomes of large numbers of microbes, plants, and other organisms, and the community of users of DOE JGI data similarly expanded and diversified. Transitioning into operating as a user facility, the DOE JGI modeled itself after other DOE user facilities, such as synchrotron light sources and supercomputer facilities, empowering the science of large numbers of investigators working in areas of relevance to energy and the environment. The JGI's approach to being a user facility is based on the concept that by focusing state-of-the-art sequencing and analysis capabilities on the best peer-reviewed ideas drawn from a broad community of scientists, the DOE JGI will effectively encourage creative approaches to DOE mission areas and produce important science. This clearly has occurred, only partially reflected in the fact that the DOE JGI has played a major role in more than 45 papers published in just the past three years alone in Nature and Science. The involvement of a large and engaged community of users working on important problems has helped maximize the impact of JGI science. A seismic technological change is presently underway at the JGI. The Sanger capillary-based sequencing process that dominated how sequencing was done in the last decade is being replaced by a variety of new processes and sequencing instruments. The JGI, with an increasing number of next-generation sequencers, whose throughput is 100- to 1,000-fold greater than the Sanger capillary-based sequencers, is increasingly focused in new directions on projects of scale and complexity not previously attempted. These new directions for the JGI come, in part, from the 2008 National Research Council report on the goals of the National Plant Genome Initiative as well as the 2007 National Research Council report on the New Science of Metagenomics. Both reports outline a crucial need for systematic large-scale surveys of the plant and microbial components of the biosphere as well as an increasing need for large-scale analysis capabilities to meet the challenge of converting sequence data into knowledge. The JGI is extensively discussed in both reports as vital to progress in these fields of major national interest. JGI's future plan for plants and microbes includes a systematic approach for investigation of these organisms at a scale requiring the special capabilities of the JGI to generate, manage, and analyze the datasets. JGI will generate and provide not only community access to these plant and microbial datasets, but also the tools for analyzing them. These activities will produce essential knowledge that will be needed if we are to be able to respond to the world's energy and environmental challenges. As the JGI Plant and Microbial programs advance, the JGI as a user facility is also evolving. The Institute has been highly successful in bending its technical and analytical skills to help users solve large complex problems of major importance, and that effort will continue unabated. The JGI will increasingly move from a central focus on 'one-off' user projects coming from small user communities to much larger scale projects driven by systematic and problem-focused approaches to selection of sequencing targets. Entire communities of scientists working in a particular field, such as feeds

Gilbert, David

2009-03-12T23:59:59.000Z

132

The human molecular clock and mutation process : a characterization using microsatellite DNA  

E-Print Network [OSTI]

In the past decade, thousands of human genomes have been catalogued, either by whole-genome sequencing or by targeted genotyping. The variability between human genomes encodes invaluable information about human traits and ...

Sun, James Xin

2012-01-01T23:59:59.000Z

133

Identifying Recent Adaptations in Large-Scale Genomic Data  

E-Print Network [OSTI]

Although several hundred regions of the human genome harbor signals of positive natural selection, few of the relevant adaptive traits and variants have been elucidated. Using full-genome sequence variation from the 1000 ...

Andersen, Kristian G.

134

Fueling Future with Algal Genomics  

SciTech Connect (OSTI)

Algae constitute a major component of fundamental eukaryotic diversity, play profound roles in the carbon cycle, and are prominent candidates for biofuel production. The US Department of Energy Joint Genome Institute (JGI) is leading the world in algal genome sequencing (http://jgi.doe.gov/Algae) and contributes of the algal genome projects worldwide (GOLD database, 2012). The sequenced algal genomes offer catalogs of genes, networks, and pathways. The sequenced first of its kind genomes of a haptophyte E.huxleyii, chlorarachniophyte B.natans, and cryptophyte G.theta fill the gaps in the eukaryotic tree of life and carry unique genes and pathways as well as molecular fossils of secondary endosymbiosis. Natural adaptation to conditions critical for industrial production is encoded in algal genomes, for example, growth of A.anophagefferens at very high cell densities during the harmful algae blooms or a global distribution across diverse environments of E.huxleyii, able to live on sparse nutrients due to its expanded pan-genome. Communications and signaling pathways can be derived from simple symbiotic systems like lichens or complex marine algae metagenomes. Collectively these datasets derived from algal genomics contribute to building a comprehensive parts list essential for algal biofuel development.

Grigoriev, Igor

2012-07-05T23:59:59.000Z

135

Functional genomics as a window on radiation stress signaling Sally A Amundson*,1  

E-Print Network [OSTI]

Functional genomics as a window on radiation stress signaling Sally A Amundson*,1 , Michael Bittner 20892, USA; 2 National Human Genome Research Institute, National Institutes of Health, Bethesda, MD before the completion of the human genome draft sequence, a number of techniques for genomic expression

136

JGI Fungal Genomics Program  

E-Print Network [OSTI]

View Supports functional genomics, user data deposition andJGI Fungal Genomics Program Igor V. Grigoriev 1 DOE Jointof California. JGI Fungal Genomics Program Contact: Igor

Grigoriev, Igor V.

2011-01-01T23:59:59.000Z

137

Fungal Genomics Program  

E-Print Network [OSTI]

strains Comparative genomics and transcriptomics of xyloseFungal Genomics Program Igor Grigoriev 1 * (complex communities Fungal Genomics Program Igor Grigoriev

Grigoriev, Igor

2012-01-01T23:59:59.000Z

138

Comparative genomics in acid mine drainage biofilm communities reveals metabolic and structural differentiation of co-occurring archaea  

E-Print Network [OSTI]

co-occurring archaea. BMC Genomics 2013 14:485. Submit yourgenomes. Yelton et al. BMC Genomics 2013, 14:485 http://work was supported by DOE Genomics: GTL project Grant No.

2013-01-01T23:59:59.000Z

139

A computational framework for the identification, cataloging, and classification of evolutionary conserved genomic DNA  

E-Print Network [OSTI]

Evolutionarily conserved genomic regions (ecores) are understudied, and yet comprise a very large percentage of the Human Genome. Highly conserved human-mouse non-coding ecores, for example, are more abundant within the ...

Saluja, Sunil K. (Sunil Kumar), 1968-

2004-01-01T23:59:59.000Z

140

2015 collaborative science projects announced | EMSL  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

call represents a unique opportunity for researchers to combine the power of genomics and molecular characterization in one research project to help advance the missions...

Note: This page contains sample records for the topic "human genome project" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


141

Current developments in genomics challenge the established framework of  

E-Print Network [OSTI]

Current developments in genomics challenge the established framework of biomedical ethics because the empirical facts of the genomic science change too fast for the reflections of ethics to keep pace with for pragmatic moral guidance1 . Recent revelations about the human genome, such as the abundance of copy

Church, George M.

142

Initial sequencing and comparative analysis of the mouse genome  

SciTech Connect (OSTI)

The sequence of the mouse genome is a key informational tool for understanding the contents of the human genome and a key experimental tool for biomedical research. Here, we report the results of an international collaboration to produce a high-quality draft sequence of the mouse genome. We also present an initial comparative analysis of the mouse and human genomes, describing some of the insights that can be gleaned from the two sequences. We discuss topics including the analysis of the evolutionary forces shaping the size, structure and sequence of the genomes; the conservation of large-scale synteny across most of the genomes; the much lower extent of sequence orthology covering less than half of the genomes; the proportions of the genomes under selection; the number of protein-coding genes; the expansion of gene families related to reproduction and immunity; the evolution of proteins; and the identification of intraspecies polymorphism.

Waterston, Robert H.; Lindblad-Toh, Kerstin; Birney, Ewan; Rogers, Jane; Abril, Josep F.; Agarwal, Pankaj; Agarwala, Richa; Ainscough, Rachel; Alexandersson, Marina; An, Peter; Antonarakis, Stylianos E.; Attwood, John; Baertsch, Robert; Bailey, Jonathon; Barlow, Karen; Beck, Stephan; Berry, Eric; Birren, Bruce; Bloom, Toby; Bork, Peer; Botcherby, Marc; Bray, Nicolas; Brent, Michael R.; Brown, Daniel G.; Brown, Stephen D.; Bult, Carol; Burton, John; Butler, Jonathan; Campbell, Robert D.; Carninci, Piero; Cawley, Simon; Chiaromonte, Francesca; Chinwalla, Asif T.; Church, Deanna M.; Clamp, Michele; Clee, Christopher; Collins, Francis S.; Cook, Lisa L.; Copley, Richard R.; Coulson, Alan; Couronne, Olivier; Cuff, James; Curwen, Val; Cutts, Tim; Daly, Mark; David, Robert; Davies, Joy; Delehaunty, Kimberly D.; Deri, Justin; Dermitzakis, Emmanouil T.; Dewey, Colin; Dickens, Nicholas J.; Diekhans, Mark; Dodge, Sheila; Dubchak, Inna; Dunn, Diane M.; Eddy, Sean R.; Elnitski, Laura; Emes, Richard D.; Eswara, Pallavi; Eyras, Eduardo; Felsenfeld, Adam; Fewell, Ginger A.; Flicek, Paul; Foley, Karen; Frankel, Wayne N.; Fulton, Lucinda A.; Fulton, Robert S.; Furey, Terrence S.; Gage, Diane; Gibbs, Richard A.; Glusman, Gustavo; Gnerre, Sante; Goldman, Nick; Goodstadt, Leo; Grafham, Darren; Graves, Tina A.; Green, Eric D.; Gregory, Simon; Guigo, Roderic; Guyer, Mark; Hardison, Ross C.; Haussler, David; Hayashizaki, Yoshihide; Hillier, LaDeana W.; Hinrichs, Angela; Hlavina, Wratko; Holzer, Timothy; Hsu, Fan; Hua, Axin; Hubbard, Tim; Hunt, Adrienne; Jackson, Ian; Jaffe, David B.; Johnson, L. Steven; Jones, Matthew; Jones, Thomas A.; Joy, Ann; Kamal, Michael; Karlsson, Elinor K.; Karolchik, Donna; Kasprzyk, Arkadiusz; Kawai, Jun; Keibler, Evan; Kells, Cristyn; Kent, W. James; Kirby, Andrew; Kolbe, Diana L.; Korf, Ian; Kucherlapati, Raju S.; Kulbokas III, Edward J.; Kulp, David; Landers, Tom; Leger, J.P.; Leonard, Steven; Letunic, Ivica; Levine, Rosie; et al.

2002-12-15T23:59:59.000Z

143

Genomic Data and Annotation from the SEED  

DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

The SEED Project has been extended to support metagenomic samples and concomitant analytical tools. Moreover, the number of genomes being introduced into SEED is growing very rapidly. Building a framework to support this growth while providing highly accurate annotations is centrally important to SEED. The project’s subsystem-based annotation strategy has become the technological foundation for addressing these challenges.(copied from Appendix 7 of Systems Biology Knowledgebase for a New Era in Biology, A Genomics:GTL Report from the May 2008 Workshop, DOE/SC-0113, Grequrick, S; Fredrickson, J.K.; Stevens, R., Pub March 1, 2009.)

Fonstein, Michael; Kogan, Yakov; Osterman, Andrei; Overbeek, Ross; Vonstein, Veronika The Fellowship for Interpretation of Genomes (FIG)

144

Dr. Mae Jemison is the principal for the 100 Year Starship Project, which envisions human travel beyond our solar system  

E-Print Network [OSTI]

, such as projects using satellite technology for healthcare delivery in West Africa and solar dish Stirling engines beyond our solar system to another star within the next 100 years. Her leadership and vision provide

Collins, Gary S.

145

Genome Analyses and Supplement Data from the International Populus Genome Consortium (IPGC)  

DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

The sequencing of the first tree genome, that of Populus, was a project initiated by the Office of Biological and Environmental Research in DOE’s Office of Science. The International Populus Genome Consortium (IPGC) was formed to help develop and guide post-sequence activities. The IPGC website, hosted at the Oak Ridge National Laboratory, provides draft sequence data as it is made available from DOE Joint Genome Institute, genome analyses for Populus, lists of related publications and resources, and the science plan. The data are available at http://www.ornl.gov/sci/ipgc/ssr_resource.htm.

International Populus Genome Consortium (IPGC)

146

Genome complexity reduction for genome-wide single nucleotide polymorphism analysis  

E-Print Network [OSTI]

Millions of single nucleotide polymorphisms (SNPs) have been identified in the human genome, and more are cataloged every day. The challenge now is to use these SNPs to discover the genetic risk factors underlying common ...

Jordan, Barbara M. (Barbara Marie), 1975-

2002-01-01T23:59:59.000Z

147

Genomics and Systems Biology  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Genomics and Systems Biology LANL leads the world in computational finishing of microbial genomes Read caption + In 2013, Los Alamos scientist Richard Sayre and his team...

148

Project Year Project Title  

E-Print Network [OSTI]

the cost of the project to labor only. The efficacy of the examples will be assessed through their useProject Year 2012-2013 Project Title Sight-Reading at the Piano Project Team Ken Johansen, Peabody) Faculty Statement The goal of this project is to create a bank of practice exercises that student pianists

Gray, Jeffrey J.

149

Project Year Project Team  

E-Print Network [OSTI]

design goals for this project include low cost (less than $30 per paddle) and robustness. The projectProject Year 2001 Project Team Faculty: Allison Okamura, Mechanical Engineering, Whiting School Project Title Haptic Display of Dynamic Systems Audience 30 to 40 students per year, enrolled

Gray, Jeffrey J.

150

Project Year Project Team  

E-Print Network [OSTI]

-year section of the summer project will cost $1344.) This project will be measured by the CER surveys conductedProject Year 2005 Project Team Sean Greenberg, Faculty, Philosophy Department, Krieger School of Arts & Sciences; Kevin Clark, Student, Philosophy Department, Krieger School of Arts & Sciences Project

Gray, Jeffrey J.

151

Probing DNA shape and methylation state on a genomic scale with DNase I  

E-Print Network [OSTI]

. It approximates the size and nuclear dif- fusion properties of a typical human transcription factor (TF) (1 status of genomic DNA. Analyzing millions of DNA backbone hydrolysis events on naked genomic DNA, we show

Rohs, Remo

152

Characterizing non-coding hits in genome-wide association studies using epigenetic data  

E-Print Network [OSTI]

Understanding the molecular basis of human disease is one of the greatest challenges of our time, and recent explosion in genetic and genomic datasets are finally putting it within reach. In the last ten years, genome-wide ...

Sarkar, Abhishek Kulshreshtha

2013-01-01T23:59:59.000Z

153

Project Year Project Team  

E-Print Network [OSTI]

Project Year 2002 Project Team Faculty: Louise Pasternack, Chemistry Department, Krieger School, Krieger School of Arts & Sciences Project Title Introductory Chemistry Lab Demonstrations Audience an interactive virtual lab manual that will facilitate understanding of the procedures and techniques required

Gray, Jeffrey J.

154

INTRODUCTION TO GENOMIC MEDICINE  

E-Print Network [OSTI]

INTRODUCTION TO GENOMIC MEDICINE Genomics play a role in 21st century research and clinical related to genomic medicine. Tentative Schedule: WHEN: WHERE: WHO CAN ATTEND? INTRODUCTION January 31 Implications of Genomics in Clinical Medicine February 7 Molecular Biology/Genetics Refresher - 1 February 14

155

Office of Sponsored Projects Annual Report: Fiscal year 2012-2013  

E-Print Network [OSTI]

,921,924, from National Institutes of Health (NIH)/National Human Genome Research Institute (NHGRI). · The top

California at Santa Cruz, University of

156

Project Year Project Title  

E-Print Network [OSTI]

Project Year 2013-2014 Project Title German Online Placement Exam Project Team Deborah Mifflin to increased cost. As well, it lacked listening comprehension, writing and speaking components providing support, we will use Blackboard for this project. The creation will require numerous steps

Gray, Jeffrey J.

157

Project Year Project Title  

E-Print Network [OSTI]

that incorporate video taped procedures for student preview. Solution This project will create videos for more to study the procedure and techniques before coming to class. Our previous fellowship project addressedProject Year 2009 Project Title Enhancing Biology Laboratory Preparation through Video

Gray, Jeffrey J.

158

Project Year Project Team  

E-Print Network [OSTI]

, there is no resource available to view the procedure before class. Solution The purpose of this project is to capture available to view the procedure before class. The purpose #12;of this project is to capture variousProject Year 2007 Project Team Kristina Obom, Faculty, Advanced Academic Programs, Krieger School

Gray, Jeffrey J.

159

Scotts Valley Energy Office and Human Capacity Building that will provide energy-efficiency services and develop sustainable renewable energy projects.  

SciTech Connect (OSTI)

The primary goal of this project is to develop a Scotts Valley Energy Development Office (SVEDO). This office will further support the mission of the Tribe's existing leadership position as the DOE Tribal Multi-County Weatherization Energy Program (TMCWEP) in creating jobs and providing tribal homes and buildings with weatherization assistance to increase energy efficiency, occupant comfort and improved indoor air quality. This office will also spearhead efforts to move the Tribe towards its further strategic energy goals of implementing renewable energy systems through specific training, resource evaluation, feasibility planning, and implementation. Human capacity building and continuing operations are two key elements of the SVEDO objectives. Therefore, the project will 1) train and employ additional Tribal members in energy efficiency, conservation and renewable resource analyses and implementation; 2) purchase materials and equipment required to implement the strategic priorities as developed by the Scotts Valley Tribe which specifically include implementing energy conservation measures and alternative energy strategies to reduce energy costs for the Tribe and its members; and 3) obtain a dedicated office and storage space for ongoing SVEDO operations.

Anderson, Temashio [Scotts Valley Band of Pomo Indians

2013-06-28T23:59:59.000Z

160

Genome sequence analysis of the model grass Brachypodium distachyon: insights into grass genome evolution  

SciTech Connect (OSTI)

Three subfamilies of grasses, the Erhardtoideae (rice), the Panicoideae (maize, sorghum, sugar cane and millet), and the Pooideae (wheat, barley and cool season forage grasses) provide the basis of human nutrition and are poised to become major sources of renewable energy. Here we describe the complete genome sequence of the wild grass Brachypodium distachyon (Brachypodium), the first member of the Pooideae subfamily to be completely sequenced. Comparison of the Brachypodium, rice and sorghum genomes reveals a precise sequence- based history of genome evolution across a broad diversity of the grass family and identifies nested insertions of whole chromosomes into centromeric regions as a predominant mechanism driving chromosome evolution in the grasses. The relatively compact genome of Brachypodium is maintained by a balance of retroelement replication and loss. The complete genome sequence of Brachypodium, coupled to its exceptional promise as a model system for grass research, will support the development of new energy and food crops

Schulman, Al

2009-08-09T23:59:59.000Z

Note: This page contains sample records for the topic "human genome project" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


161

Complete genome sequence of Acidimicrobium ferrooxidans type strain (ICPT)  

SciTech Connect (OSTI)

Acidimicrobium ferrooxidans (Clark and Norris 1996) is the sole and type species of the genus, which until recently was the only genus within the actinobacterial family Acidimicrobiaceae and in the order Acidomicrobiales. Rapid oxidation of iron pyrite during autotrophic growth in the absence of an enhanced CO2 concentration is characteristic for A. ferrooxidans. Here we describe the features of this organism, together with the complete genome sequence, and annotation. This is the first complete genome sequence of the order Acidomicrobiales, and the 2,158,157 bp long single replicon genome with its 2038 protein coding and 54 RNA genes is part of the Genomic Encyclopedia of Bacteria and Archaea project.

Clum, Alicia; Nolan, Matt; Lang, Elke; Glavina Del Rio, Tijana; Tice, Hope; Copeland, Alex; Cheng, Jan-Fang; Lucas, Susan; Chen, Feng; Bruce, David; Goodwin, Lynne; Pitluck, Sam; Ivanova, Natalia; Mavrommatis, Konstantinos; Mikhailova, Natalia; Pati, Amrita; Chen, Amy; Palaniappan, Krishna; Goker, Markus; Spring, Stefan; Land, Miriam; Hauser, Loren; Chang, Yun-Juan; Jefferies, Cynthia C.; Chain, Patrick; Bristow, James; Eisen, Jonathan A.; Markowitz, Victor; Hugenholtz, Philip; Kyrpides, Nikos C.; Klenk, Hans-Peter; Lapidus, Alla

2009-05-20T23:59:59.000Z

162

Project Year Project Team  

E-Print Network [OSTI]

Project Year 2002 Project Team Faculty: Gregory Hager, Computer Science, Whiting School of Engineering Fellow: Alan Chen, Biomedical Engineering, Whiting School of Engineering Project Title Robotics is complicated, time-consuming, and costly, making a robot for an introductory-level class is not practical

Gray, Jeffrey J.

163

Project Proposal Project Logistics  

E-Print Network [OSTI]

Project Proposal · Project Logistics: ­ 2-3 person teams ­ Significant implementation, worth 55 and anticipated cost of copying to/from host memory. IV. Intellectual Challenges - Generally, what makes this computation worthy of a project? - Point to any difficulties you anticipate at present in achieving high

Hall, Mary W.

164

Project Year Project Title  

E-Print Network [OSTI]

operators, matrix indexing, vector computations, loops, functions, and plotting graphs, among others basic arithmetic operators, matrix indexing, and vector computations in MATLAB. After creatingProject Year 2011-2012 Project Title Online Tutorial for MATLAB Project Team Eileen Haase, Whiting

Gray, Jeffrey J.

165

Project Year Project Team  

E-Print Network [OSTI]

Project Year 2005 Project Team Krysia Hudson, Faculty, School of Nursing, Undergraduate Instruction for Educational Resources Project Title Enhanced Web-based Learning Environments for Beginning Nursing Students (e.g., demonstrations of procedures or tasks) into the WBL systems, it will be possible to increase

Gray, Jeffrey J.

166

Project Year Project Team  

E-Print Network [OSTI]

Project Year 2002 Project Team Faculty: Michael McCloskey, Cognitive Science/Neuroscience, Krieger of Arts & Sciences Project Title Cognitive Neuropsychology Audience The initial audience to access. The current procedure calls for individual students or researchers to contact the faculty member

Gray, Jeffrey J.

167

An Investigation of Insulator Proteins in Mosquito Genomes  

E-Print Network [OSTI]

of transgenes in mosquito species. The use of insulator sequences to flank transgenes may have the ability to overcome position effects caused by the genomic environment surrounding the insertion site. CTCF is a multifunctional protein, conserved from humans...

Johanson, Michael

2013-08-02T23:59:59.000Z

168

The Genome of the Western Clawed Frog Xenopus tropicalis  

SciTech Connect (OSTI)

The western clawed frog Xenopus tropicalis is an important model for vertebrate development that combines experimental advantages of the African clawed frog Xenopus laevis with more tractable genetics. Here we present a draft genome sequence assembly of X. tropicalis. This genome encodes over 20,000 protein-coding genes, including orthologs of at least 1,700 human disease genes. Over a million expressed sequence tags validated the annotation. More than one-third of the genome consists of transposable elements, with unusually prevalent DNA transposons. Like other tetrapods, the genome contains gene deserts enriched for conserved non-coding elements. The genome exhibits remarkable shared synteny with human and chicken over major parts of large chromosomes, broken by lineage-specific chromosome fusions and fissions, mainly in the mammalian lineage.

Hellsten, Uffe; Harland, Richard M.; Gilchrist, Michael J.; Hendrix, David; Jurka, Jerzy; Kapitonov, Vladimir; Ovcharenko, Ivan; Putnam, Nicholas H.; Shu, Shengqiang; Taher, Leila; Blitz, Ira L.; Blumberg, Bruce; Dichmann, Darwin S.; Dubchak, Inna; Amaya, Enrique; Detter, John C.; Fletcher, Russell; Gerhard, Daniela S.; Goodstein, David; Graves, Tina; Grigoriev, Igor V.; Grimwood, Jane; Kawashima, Takeshi; Lindquist, Erika; Lucas, Susan M.; Mead, Paul E.; Mitros, Therese; Ogino, Hajime; Ohta, Yuko; Poliakov, Alexander V.; Pollet, Nicolas; Robert, Jacques; Salamov, Asaf; Sater, Amy K.; Schmutz, Jeremy; Terry, Astrid; Vize, Peter D.; Warren, Wesley C.; Wells, Dan; Wills, Andrea; Wilson, Richard K.; Zimmerman, Lyle B.; Zorn, Aaron M.; Grainger, Robert; Grammer, Timothy; Khokha, Mustafa K.; Richardson, Paul M.; Rokhsar, Daniel S.

2009-10-01T23:59:59.000Z

169

Project Year Project Title  

E-Print Network [OSTI]

Project Year 2011-2012 Project Title Using M-Health and GIS Technology in the Field to Improve-specialized, but practically useless skill. Solution One goal of this summer's Applied Geographic Information Systems in Public lessons about observational epidemiology. Technologies Used Geographic Info System (GIS), Blackboard

Gray, Jeffrey J.

170

Genome Clone Libraries and Data from the Integrated Molecular Analysis of Genomes and their Expression (I.M.A.G.E.) Consortium  

DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

The I.M.A.G.E. Consortium was initiated in 1993 by four academic groups on a collaborative basis after informal discussions led to a common vision of how to achieve an important goal in the study of the human genome: the Integrated Molecular Analysis of Genomes and their Expression Consortium's primary goal is to create arrayed cDNA libraries and associated bioinformatics tools, and make them publicly available to the research community. The primary organisms of interest include intensively studied mammalian species, including human, mouse, rat and non-human primate species. The Consortium has also focused on several commonly studied model organisms; as part of this effort it has arrayed cDNAs from zebrafish, and Fugu (pufferfish) as well as Xenopus laevis and X. tropicalis (frog). Utilizing high speed robotics, over nine million individual cDNA clones have been arrayed into 384-well microtiter plates, and sufficient replicas have been created to distribute copies both to sequencing centers and to a network of five distributors located worldwide. The I.M.A.G.E. Consortium represents the world's largest public cDNA collection, and works closely with the National Institutes of Health's Mammalian Gene Collection(MGC) to help it achieve its goal of creating a full-length cDNA clone for every human and mouse gene. I.M.A.G.E. is also a member of the ORFeome Collaboration, working to generate a complete set of expression-ready open reading frame clones representing each human gene. Custom informatics tools have been developed in support of these projects to better allow the research community to select clones of interest and track and collect all data deposited into public databases about those clones and their related sequences. I.M.A.G.E. clones are publicly available, free of any royalties, and may be used by anyone agreeing with the Consortium's guidelines.

171

Project Accounts  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Project Accounts Project Accounts Overview Project accounts are designed to facilitate collaborative computing by allowing multiple users to use the same account. All actions...

172

Webinar: Materials Genome Initative  

Broader source: Energy.gov [DOE]

Audio recording and text version of the Fuel Cell Technologies Office webinar titled "Materials Genome Initiative," originally presented on December 2, 2014.

173

Sequence modelling and an extensible data model for genomic database  

SciTech Connect (OSTI)

The Human Genome Project (HGP) plans to sequence the human genome by the beginning of the next century. It will generate DNA sequences of more than 10 billion bases and complex marker sequences (maps) of more than 100 million markers. All of these information will be stored in database management systems (DBMSs). However, existing data models do not have the abstraction mechanism for modelling sequences and existing DBMS's do not have operations for complex sequences. This work addresses the problem of sequence modelling in the context of the HGP and the more general problem of an extensible object data model that can incorporate the sequence model as well as existing and future data constructs and operators. First, we proposed a general sequence model that is application and implementation independent. This model is used to capture the sequence information found in the HGP at the conceptual level. In addition, abstract and biological sequence operators are defined for manipulating the modelled sequences. Second, we combined many features of semantic and object oriented data models into an extensible framework, which we called the Extensible Object Model'', to address the need of a modelling framework for incorporating the sequence data model with other types of data constructs and operators. This framework is based on the conceptual separation between constructors and constraints. We then used this modelling framework to integrate the constructs for the conceptual sequence model. The Extensible Object Model is also defined with a graphical representation, which is useful as a tool for database designers. Finally, we defined a query language to support this model and implement the query processor to demonstrate the feasibility of the extensible framework and the usefulness of the conceptual sequence model.

Li, Peter Wei-Der (California Univ., San Francisco, CA (United States) Lawrence Berkeley Lab., CA (United States))

1992-01-01T23:59:59.000Z

174

Sequence modelling and an extensible data model for genomic database  

SciTech Connect (OSTI)

The Human Genome Project (HGP) plans to sequence the human genome by the beginning of the next century. It will generate DNA sequences of more than 10 billion bases and complex marker sequences (maps) of more than 100 million markers. All of these information will be stored in database management systems (DBMSs). However, existing data models do not have the abstraction mechanism for modelling sequences and existing DBMS`s do not have operations for complex sequences. This work addresses the problem of sequence modelling in the context of the HGP and the more general problem of an extensible object data model that can incorporate the sequence model as well as existing and future data constructs and operators. First, we proposed a general sequence model that is application and implementation independent. This model is used to capture the sequence information found in the HGP at the conceptual level. In addition, abstract and biological sequence operators are defined for manipulating the modelled sequences. Second, we combined many features of semantic and object oriented data models into an extensible framework, which we called the ``Extensible Object Model``, to address the need of a modelling framework for incorporating the sequence data model with other types of data constructs and operators. This framework is based on the conceptual separation between constructors and constraints. We then used this modelling framework to integrate the constructs for the conceptual sequence model. The Extensible Object Model is also defined with a graphical representation, which is useful as a tool for database designers. Finally, we defined a query language to support this model and implement the query processor to demonstrate the feasibility of the extensible framework and the usefulness of the conceptual sequence model.

Li, Peter Wei-Der [California Univ., San Francisco, CA (United States); [Lawrence Berkeley Lab., CA (United States)

1992-01-01T23:59:59.000Z

175

FUNCTIONAL GENOMICS Program of Study  

E-Print Network [OSTI]

FUNCTIONAL GENOMICS Program of Study Research Areas Students Applying Correspondence Graduate Genomics. Students receive training in the biological, physical and computational sciences through of primary institutional affiliation. The Functional Genomics program is administered through the Graduate

Thomas, Andrew

176

Enhancer Identification through Comparative Genomics  

E-Print Network [OSTI]

through Comparative Genomics Axel Visel, James Bristow andWalnut Creek, CA 94598 USA. Genomics Division, MS 84-171,Len A. Pennacchio, Genomics Division, One Cyclotron Road, MS

Visel, Axel; Bristow, James; Pennacchio, Len A.

2006-01-01T23:59:59.000Z

177

The Future of Microbial Genomics  

SciTech Connect (OSTI)

Nikos Kyrpides, head of the Genome Biology group at the DOE Joint Genome Institute discusses current challenges in the field of microbial genomics on June 2, 2010 at the "Sequencing, Finishing, Analysis in the Future" meeting in Santa Fe, NM

Kyrpides, Nikos [Genome Biology group at the DOE Joint Genome Institute

2010-06-02T23:59:59.000Z

178

Degree project in Communication Systems  

E-Print Network [OSTI]

Degree project in Communication Systems Second level, 30.0 HEC Stockholm, Sweden E L M I R A K H O-bönor till FXML. Den föreslagna algoritmen har sedan utvärderats genom automatiserade mjukvarutester

Maguire Jr., Gerald Q.

179

(New hosts and vectors for genome cloning)  

SciTech Connect (OSTI)

The main goal of our project remains the development of new bacterial hosts and vectors for the stable propagation of human DNA clones in E. coli. During the past six months of our current budget period, we have (1) continued to develop new hosts that permit the stable maintenance of unstable features of human DNA, and (2) developed a series of vectors for (a) cloning large DNA inserts, (b) assessing the frequency of human sequences that are lethal to the growth of E. coli, and (c) assessing the stability of human sequences cloned in M13 for large-scale sequencing projects.

Not Available

1991-01-01T23:59:59.000Z

180

Automated Microbial Genome Annotation  

SciTech Connect (OSTI)

Miriam Land of the DOE Joint Genome Institute at Oak Ridge National Laboratory gives a talk on the current state and future challenges of moving toward automated microbial genome annotation at the "Sequencing, Finishing, Analysis in the Future" meeting in Santa Fe, NM

Land, Miriam [DOE Joint Genome Institute at Oak Ridge National Laboratory

2009-05-29T23:59:59.000Z

Note: This page contains sample records for the topic "human genome project" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


181

Genetic association with overall survival of taxane-treated lung cancer patients - a genome-wide association study in human lymphoblastoid cell lines followed by a clinical association study  

E-Print Network [OSTI]

Background: Taxane is one of the first line treatments of lung cancer. In order to identify novel single nucleotide polymorphisms (SNPs) that might contribute to taxane response, we performed a genome-wide association study ...

Niu, Nifang

182

Procedures for Preparing the Research Project Proposal (Revised: March 5, 2010) 1 PROCEDURES FOR A PROJECT  

E-Print Network [OSTI]

FOR A PROJECT: for the Master of Science in Human-Computer InteractionProcedures for Preparing the Research Project Proposal (Revised: March 5, 2010) 1 PROCEDURES the Research Project Proposal (Revised: March 5, 2010) 2 Contents HCI GRADUATE FACULTY

Zhou, Yaoqi

183

Evolutionary Genomics of Salmonella enterica Subspecies  

E-Print Network [OSTI]

M. 2013. Evolutionary genomics of Salmonella entericaEvolutionary Genomics of Salmonella enterica Subspecies

2013-01-01T23:59:59.000Z

184

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data  

E-Print Network [OSTI]

Next-generation DNA sequencing (NGS) projects, such as the 1000 Genomes Project, are already revolutionizing our understanding of genetic variation among individuals. However, the massive data sets generated by NGS—the ...

McKenna, Aaron

185

E-Print Network 3.0 - administered recombinant human Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

that recombination rates vary greatly across the human genome, by at least two orders of magnitude. Linkage... . & Weber, J. L. Comprehensive human genetic maps: Individual...

186

Project Fact Sheet Project Brief  

E-Print Network [OSTI]

Project Fact Sheet Project Brief: Construction Project Team: Project Facts & Figures: Budget: £500,000 Funding Source: Capital Construction Project Programme: Start on Site: October 2010 End Date : April 2011 Occupation Date: n/a For further information contact Project Manager as listed above or the Imperial College

187

Project Fact Sheet Project Brief  

E-Print Network [OSTI]

Project Fact Sheet Project Brief: This project refurbished half of the 5th and 7th floors on the Faculty of Medicine, please visit: http://www1.imperial.ac.uk/medicine/ Construction Project Team: Project Facts & Figures: Budget: £3,500,000 Funding Source: SRIF III Construction Project Programme: Start

188

Genome sequencing and analysis of the model grass Brachypodium distachyon  

E-Print Network [OSTI]

energy and food crops. Grasses provide the bulk of human nutrition, and highly productive grasses, provide the bulk of human nutrition and are poised to become major sources of renewable energy. Here we. The high-quality genome sequence, coupled with ease of cultivation and transformation, small size and rapid

Green, Pamela

189

Human evolutionary genomics: ethical and interpretive issues  

E-Print Network [OSTI]

for Biomedical Ethics, Stanford University, Palo Alto, CA, USA 4 Departments of Genetics and Biology, University Bottleneck: an event in the history of a population when the population size decreases sharply, resulting the population as competing variants are wiped out. Directional selection: a form of natural selection in which

190

Compressing and Querrying the Human Genome /  

E-Print Network [OSTI]

Acknowledgement . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Acknowledgements . . . . . . . . . . . . . . . . . . . . . . . . . . .1.7 Acknowledgement . . . . . . . . . . . . .

Kozanitis, Christos A.

2013-01-01T23:59:59.000Z

191

History of the DOE Human Genome Program  

Office of Scientific and Technical Information (OSTI)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary)morphinan antagonist Journal Article: Crystal structureComposite--FORRemarksHEATING DISTRIBUTIONSHistory of the

192

Comparative and Functional Genomics Comp Funct Genom 2003; 4: 239245.  

E-Print Network [OSTI]

Comparative and Functional Genomics Comp Funct Genom 2003; 4: 239­245. Published online 1 April://www.botany.iastate.edu/mash/metnetex/metabolicnetex.html) is pub- licly available software in development for analysis of genome-wide RNA, protein and metabolite in the post-genome era is to understand how interactions among molecules in a cell determine its form

Wurtele, Eve Syrkin

193

Update on Genomic Studies of Algae Paths toward Algal Genomics  

E-Print Network [OSTI]

Update on Genomic Studies of Algae Paths toward Algal Genomics Arthur R. Grossman* The Carnegie of genomic information that is being used to help researchers understand the gene content of organisms, how the expression of genes. In this introductory manuscript, I discuss select algae and how genomics is impacting

194

Comparative and Functional Genomics Comp Funct Genom 2003; 4: 3136.  

E-Print Network [OSTI]

Comparative and Functional Genomics Comp Funct Genom 2003; 4: 31­36. Published online in Wiley and mitochondria contain genomes John F. Allen* Plant Biochemistry, Center for Chemistry and Chemical Engineering that the nucleotide sequences of mitochondrial and chloroplast genomes would provide the answer has proved unfounded

Allen, John F.

195

Eukaryotic Genomics Data from the DOE Joint Genome Institute (JGI)  

DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

From the JGI webportal users can choose Eukaryotic genomes from a photo list, access the JGI FTP directories to download data files, use the Tree of Life navigation tool, or choose a genome and go directly to a website specific to that one genome. The individual sites include direct access to download sequence files, BLAST, search, view and navigate the genomic annotations.

196

Genome Structure Gallery from the Mycobacterium Tuberculosis Structual Genomics Consortium  

DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

The TB Structural Genomics Consortium works with the structures of proteins from M. tuberculosis, analyzing these structures in the context of functional information that currently exists and that the Consortium generates. The database of linked structural and functional information constructed from this project will form a lasting basis for understanding M. tuberculosis pathogenesis and for structure-based drug design. The Consortium's structural and functional information is publicly available. The Structures Gallery makes more than 650 total structures available by PDB identifier. Some of these are not consortium targets, but all are viewable in 3D color and can be manipulated in various ways by Jmol, an open-source Java viewer for chemical structures in 3D from http://www.jmol.org/

197

Comparative genomics of the core and accessory genomes of 48 Sinorhizobium strains comprising five genospecies  

E-Print Network [OSTI]

annotation and comparative genomics. Database (Oxford) 2009,et al. : Comparative genomics of the core and accessoryComparative genomics of the core and accessory genomes of 48

2013-01-01T23:59:59.000Z

198

Project Management Project Managment  

E-Print Network [OSTI]

­ Inspired by agile methods #12;Background · Large-scale software development & IT projects, plagued relations #12;One Agile Approach to Scheduling · The creative nature of game development resist heavy up Problems ­incompatible platforms, 3rd party etc. #12;Is Games Development Similar? · Yes & No

Stephenson, Ben

199

Project Year Project Team  

E-Print Network [OSTI]

An Engineer's Guide to the Structures of Baltimore Audience Students from the Krieger School of Arts City, interfaced through a course website, the team will integrate descriptions of structural behavior format. Technologies Used HTML/Web Design, MySQL Project Abstract Structural analysis is typically taught

Gray, Jeffrey J.

200

The Center for integrative genomics  

E-Print Network [OSTI]

The Center for integrative genomics Report 2005­2006 #12;Presentation Director's message 4 Scientific advisory committee 6 Organigram of the CIG 7 research The structure and function of genomes and their evolution alexandrereymond ­ Genome structure and expression 10 henrikKaessmann ­ Evolutionary genomics 12

Kaessmann, Henrik

Note: This page contains sample records for the topic "human genome project" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


201

CRIS Project Internal DASNR Compliance Checklist  

E-Print Network [OSTI]

CRIS Project Internal DASNR Compliance Checklist Researcher's Name: Department: Address / Phone: Project Title: Does this project involve research with: Human Subjects Yes No If yes, attach copy of IRB to Animals, Plants, or Humans Radioactive Materials or Yes No If yes, attach copy of Radiation Sa X

Ghajar, Afshin J.

202

Genomic library construction  

DOE Patents [OSTI]

Compositions and methods for amplifying nucleic acid sequences from a single cell are provided. Compositions and methods for constructing a genomic library from a single cell are also provided.

Church, George M. (Brookline, MA); Zhang, Kun (San Diego, CA)

2011-07-26T23:59:59.000Z

203

Project Fact Sheet Project Update  

E-Print Network [OSTI]

Project Fact Sheet Project Update: Project Brief: A state of the art facility, at Hammersmith information visit the Faculty of Medicine web pages http://www1.imperial.ac.uk/medicine/ Construction Project Team: Project Facts & Figures: Budget: £60 000 000 Funding Source: SRIF II (Imperial College), GSK, MRC

204

Project Fact Sheet Project Update  

E-Print Network [OSTI]

Project Fact Sheet Project Update: Project Brief: The refurbishment of the instrumentation equipment. This project encompasses refurbishment work on over 1,150m2 of laboratory space across four, the completed project will allow researchers to expand their work in satellite instrumentation, the fabrication

205

Project Fact Sheet Project Brief  

E-Print Network [OSTI]

Project Fact Sheet Project Brief: In the first phase of the Union Building re.union.ic.ac.uk/marketing/building Construction Project Team: Project Facts & Figures: Budget: £1,400,000 Funding Source: Capital Plan and Imperial College Union reserves Construction Project Programme: Start on Site: August 2006 End Date: March

206

Volume Project  

E-Print Network [OSTI]

Math 13900. Volume Project. For the following project, you may use any materials. This must be your own original creation. Construct a right pyramid with a base ...

rroames

2010-01-12T23:59:59.000Z

207

Genomics, Gene Expression and Other Studies in Soybean Rust  

E-Print Network [OSTI]

Joint Genome Institute Genomics, Gene Expression and otherRust Martha Lucía Posada-Buitrago Ph.D Genomics DivisionEvolutionary Genomics DOE- Joint Genome Institute Lawrence

Posada-Buitrago, Martha Lucia

2005-01-01T23:59:59.000Z

208

Bioinformatics and Genomics Degree Requirements Booklet  

E-Print Network [OSTI]

Bioinformatics and Genomics Degree Requirements Booklet Fall 2010 #12;Contents Course Requirements Bioinformatics and Genomics Curriculum -------------------------------------------------------8 General #12;Bioinformatics and Genomics Option (BG

dePamphilis, Claude

209

Fueling the Future with Fungal Genomics  

E-Print Network [OSTI]

JW. 2010. China's fungal genomics initiative: a whitepaper.and Saccharomycotina. BMC Genomics. 8, 325. Bailly J,Harnessing ectomycorrhizal genomics for ecological insights.

Grigoriev, Igor V.

2011-01-01T23:59:59.000Z

210

VISTA - computational tools for comparative genomics  

E-Print Network [OSTI]

tools for comparative genomics Kelly A. Frazer 1 , LiorBerkeley, CA, 94720 Genomics Division, Lawrence Berkeleymultiple comparative genomics tools and provides users with

Frazer, Kelly A.; Pachter, Lior; Poliakov, Alexander; Rubin, Edward M.; Dubchak, Inna

2004-01-01T23:59:59.000Z

211

Project Controls  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

Project controls are systems used to plan, schedule, budget, and measure the performance of a project/program. The cost estimation package is one of the documents that is used to establish the baseline for project controls. This chapter gives a brief description of project controls and the role the cost estimation package plays.

1997-03-28T23:59:59.000Z

212

A study of the necessary and optimal conditions for success in the most challenging human endeavors : modem day Manhattan Projects are needed for overcoming contemporary global challenges  

E-Print Network [OSTI]

It is possible to categorize four contemporary challenges as the greatest threats to global well-being and the persistence of humankind. These challenges are global climate and ecological change, poor human health management, ...

Chowdhury, Anando A

2012-01-01T23:59:59.000Z

213

Development of an endocrine genomics virtual research environment for Australia: building on success .  

E-Print Network [OSTI]

??The $47m Australian National eResearch Collaboration Tools and Resources (NeCTAR - www.nectar.org.au) project has recently funded an initiative to establish an Australia-wide endocrine genomics virtual… (more)

Sinnott, Richard O.

2013-01-01T23:59:59.000Z

214

The Impact of Spatial Structure on Viral Genomic Diversity Generated during Adaptation to Thermal Stress  

E-Print Network [OSTI]

(Seeds, Genomics, Biofuels) for a portion of this study. There are no patents, products in development: This project was supported by grants from the National Center for Research Resources (5P20RR016448 or marketed products to decl

Krone, Steve

215

Computational genomics : mapping, comparison, and annotation of genomes  

E-Print Network [OSTI]

The field of genomics provides many challenges to computer scientists and mathematicians. The area of computational genomics has been expanding recently, and the timely application of computer science in this field is ...

Batzoglou, Serafim

2000-01-01T23:59:59.000Z

216

Comparative Analysis of Genome Sequences with VISTA  

DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

VISTA is a comprehensive suite of programs and databases developed by and hosted at the Genomics Division of Lawrence Berkeley National Laboratory. They provide information and tools designed to facilitate comparative analysis of genomic sequences. Users have two ways to interact with the suite of applications at the VISTA portal. They can submit their own sequences and alignments for analysis (VISTA servers) or examine pre-computed whole-genome alignments of different species. A key menu option is the Enhancer Browser and Database at http://enhancer.lbl.gov/. The VISTA Enhancer Browser is a central resource for experimentally validated human noncoding fragments with gene enhancer activity as assessed in transgenic mice. Most of these noncoding elements were selected for testing based on their extreme conservation with other vertebrates. The results of this enhancer screen are provided through this publicly available website. The browser also features relevant results by external contributors and a large collection of additional genome-wide conserved noncoding elements which are candidate enhancer sequences. The LBL developers invite external groups to submit computational predictions of developmental enhancers. As of 10/19/2009 the database contains information on 1109 in vivo tested elements - 508 elements with enhancer activity.

Dubchak, Inna

217

Project Fact Sheet Project Update  

E-Print Network [OSTI]

Project Fact Sheet Project Update: Project Brief: The works cover the refurbishment of floors 4, 5, with `wet' labs for molecular biology, materials characterisation, cell culture and flow studies, and `dry operating theatre. The Bionanotechnology Centre is one of the projects funded from the UK Government's £20

218

Phytozome: a Tool for Green Plant Comparative Genomics  

DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

Phytozome is a joint project of the Department of Energy's Joint Genome Institute and the Center for Integrative Genomics to facilitate comparative genomic studies amongst green plants. Clusters of orthologous and paralogous genes that represent the modern descendents of ancestral gene sets are constructed at key phylogenetic nodes. These clusters allow easy access to clade specific orthology/paralogy relationships as well as clade specific genes and gene expansions. As of release v4.0, Phytozome provides access to nine sequenced and annotated green plant genomes, eight of which have been clustered into gene families at six evolutionarily significant nodes. Where possible, each gene has been annotated with PFAM, KOG, KEGG, and PANTHER assignments, and publicly available annotations from RefSeq, UniProt, TAIR, JGI are hyper-linked and searchable. [Copied from the Overview at http://www.phytozome.net/Phytozome_info.php

219

Local chromatin structure of heterochromatin regulates repeatedDNA stability, nucleolus structure, and genome integrity  

SciTech Connect (OSTI)

Heterochromatin constitutes a significant portion of the genome in higher eukaryotes; approximately 30% in Drosophila and human. Heterochromatin contains a high repeat DNA content and a low density of protein-encoding genes. In contrast, euchromatin is composed mostly of unique sequences and contains the majority of single-copy genes. Genetic and cytological studies demonstrated that heterochromatin exhibits regulatory roles in chromosome organization, centromere function and telomere protection. As an epigenetically regulated structure, heterochromatin formation is not defined by any DNA sequence consensus. Heterochromatin is characterized by its association with nucleosomes containing methylated-lysine 9 of histone H3 (H3K9me), heterochromatin protein 1 (HP1) that binds H3K9me, and Su(var)3-9, which methylates H3K9 and binds HP1. Heterochromatin formation and functions are influenced by HP1, Su(var)3-9, and the RNA interference (RNAi) pathway. My thesis project investigates how heterochromatin formation and function impact nuclear architecture, repeated DNA organization, and genome stability in Drosophila melanogaster. H3K9me-based chromatin reduces extrachromosomal DNA formation; most likely by restricting the access of repair machineries to repeated DNAs. Reducing extrachromosomal ribosomal DNA stabilizes rDNA repeats and the nucleolus structure. H3K9me-based chromatin also inhibits DNA damage in heterochromatin. Cells with compromised heterochromatin structure, due to Su(var)3-9 or dcr-2 (a component of the RNAi pathway) mutations, display severe DNA damage in heterochromatin compared to wild type. In these mutant cells, accumulated DNA damage leads to chromosomal defects such as translocations, defective DNA repair response, and activation of the G2-M DNA repair and mitotic checkpoints that ensure cellular and animal viability. My thesis research suggests that DNA replication, repair, and recombination mechanisms in heterochromatin differ from those in euchromatin. Remarkably, human euchromatin and fly heterochromatin share similar features; such as repeated DNA content, intron lengths and open reading frame sizes. Human cells likely stabilize their DNA content via mechanisms and factors similar to those in Drosophila heterochromatin. Furthermore, my thesis work raises implications for H3K9me and chromatin functions in complex-DNA genome stability, repeated DNA homogenization by molecular drive, and in genome reorganization through evolution.

Peng, Jamy C.

2007-05-05T23:59:59.000Z

220

Microbial Genomics Data from the DOE Joint Genome Institute (JGI)  

DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

As of March 2008, The Joint Genome Institute has released 296 Prokaryotic microbial sites, with 216 in finished status.

Note: This page contains sample records for the topic "human genome project" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


221

Genome Science/Technologies  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation ProposedUsingFun with Big Sky Learning Fun withGenepoolCrystals.Genome Genome

222

Clinical Microfluidics for Neutrophil Genomics and Proteomics...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Clinical Microfluidics for Neutrophil Genomics and Proteomics. Clinical Microfluidics for Neutrophil Genomics and Proteomics. Abstract: Neutrophils play critical roles in...

223

2012 U.S. Department of Energy: Joint Genome Institute: Progress Report  

SciTech Connect (OSTI)

The mission of the U.S. Department of Energy Joint Genome Institute (DOE JGI) is to serve the diverse scientific community as a user facility, enabling the application of large-scale genomics and analysis of plants, microbes, and communities of microbes to address the DOE mission goals in bioenergy and the environment. The DOE JGI's sequencing efforts fall under the Eukaryote Super Program, which includes the Plant and Fungal Genomics Programs; and the Prokaryote Super Program, which includes the Microbial Genomics and Metagenomics Programs. In 2012, several projects made news for their contributions to energy and environment research.

Gilbert, David [DOE JGI Public Affairs Manager] [DOE JGI Public Affairs Manager

2013-01-01T23:59:59.000Z

224

Circle Project  

E-Print Network [OSTI]

This project asks students to decide if a collection of points in space do or do not lie on a ... The project is accessible to linear algebra students who have studied ...

225

SHORT REVIEW Butterfly genomics eclosing  

E-Print Network [OSTI]

SHORT REVIEW Butterfly genomics eclosing P Beldade1 , WO McMillan2 and A Papanicolaou3 1 Section to an explosion of genomic data and the emergence of new research avenues. Evolutionary and ecological functional genomics, with its focus on the genes that affect ecological success and adaptation in natural populations

Beldade, Patrícia

226

International milk genomics consortium  

E-Print Network [OSTI]

University, Wooster, OH 44691, USA c University of Idaho, Moscow, ID 83844, USA d University of Colorado. The general goals of the Milk Genomics Consortium are to link the scientific community through milk and geno value of milk's components is known (German, Dillard, & Ward, 2002). The scientific challenge, therefore

Rocke, David M.

227

E-Print Network 3.0 - africae genome reveals Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

and Medicine 2 Vol 464|1 April 2010 Has the revolution arrived? Summary: of human genomics, FrancisCollins finds five key lessons for the future of personalized medicine... --...

228

Assembly of the Candida albicans genome into sixteen supercontigs aligned on the eight chromosomes  

E-Print Network [OSTI]

Background: The 10.9× genomic sequence of Candida albicans, the most important human fungal pathogen, was published in 2004. Assembly 19 consisted of 412 supercontigs, of which 266 were a haploid set, since this fungus is ...

van het Hoog, Marco

229

Genomic signatures of sex, selection and speciation in the microbial world  

E-Print Network [OSTI]

Understanding the microbial world is key to understanding global biogeochemistry, human health and disease, yet this world is largely inaccessible. Microbial genomes, an increasingly accessible data source, provide an ideal ...

Shapiro, B. Jesse (Benjamin Jesse)

2010-01-01T23:59:59.000Z

230

Deep-sea vent -proteobacterial genomes provide insights into emergence of pathogens  

E-Print Network [OSTI]

% of the human population is infected by Helicobacter pylori, which causes gastric ulcer and cancer (12, Helicobacter and Campylobacter species. The deep-sea vent -proteobacterial genomes encode for multiple systems

Reysenbach, Anna-Louise

231

Mining data from 1000 genomes to identify the causal variant in regions under positive selection  

E-Print Network [OSTI]

The human genome contains hundreds of regions in which the patterns of genetic variation indicate recent positive natural selection, yet for most of these the underlying gene and the advantageous mutation remain unknown. ...

Grossman, Sharon Rachel

232

GeneJax: A Prototype CAD tool in support of Genome Refactoring  

E-Print Network [OSTI]

Refactoring is a technique used by computer scientists for improving program design. The Endy Laboratory has adapted this process to make the genomes of biological organisms more amenable to human understanding and design ...

Anand, Ishan

2006-05-26T23:59:59.000Z

233

Connecting Genomic Alterations to Cancer Biology with Proteomics: The NCI Clinical Proteomic Tumor Analysis Consortium  

SciTech Connect (OSTI)

The National Cancer Institute (NCI) Clinical Proteomic Tumor Analysis Consortium is applying the latest generation of proteomic technologies to genomically annotated tumors from The Cancer Genome Atlas (TCGA) program, a joint initiative of the NCI and the National Human Genome Research Institute. By providing a fully integrated accounting of DNA, RNA, and protein abnormalities in individual tumors, these datasets will illuminate the complex relationship between genomic abnormalities and cancer phenotypes, thus producing biologic insights as well as a wave of novel candidate biomarkers and therapeutic targets amenable to verifi cation using targeted mass spectrometry methods.

Ellis, Matthew; Gillette, Michael; Carr, Steven A.; Paulovich, Amanda G.; Smith, Richard D.; Rodland, Karin D.; Townsend, Reid; Kinsinger, Christopher; Mesri, Mehdi; Rodriguez, Henry; Liebler, Daniel

2013-10-03T23:59:59.000Z

234

ECRbase: Database of Evolutionary Conserved Regions, Promoters, and Transcription Factor Binding Sites in Vertebrate Genomes  

DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

Evolutionary conservation of DNA sequences provides a tool for the identification of functional elements in genomes. This database of evolutionary conserved regions (ECRs) in vertebrate genomes features a database of syntenic blocks that recapitulate the evolution of rearrangements in vertebrates and a comprehensive collection of promoters in all vertebrate genomes generated using multiple sources of gene annotation. The database also contains a collection of annotated transcription factor binding sites (TFBSs) in evolutionary conserved and promoter elements. ECRbase currently includes human, rhesus macaque, dog, opossum, rat, mouse, chicken, frog, zebrafish, and fugu genomes. (taken from paper in Journal: Bioinformatics, November 7, 2006, pp. 122-124

Loots, Gabriela G. (LLNL); Ovcharenko, I. (LLNL)

235

Contextual Genomics: Chris Wagner CEO cwagner@contextualgenomics.com Personalized Medicine Initiative (PMI): Rob Fraser -COO -robertfr@mail.ubc.ca  

E-Print Network [OSTI]

Initiative (PMI): Rob Fraser - COO - robertfr@mail.ubc.ca Contextual Genomics and PMI have launched mutations and designed to improve clinical outcomes and reduce costs. The project is being managed by PMI laboratory, LifeLabs. "NationalAccessProjectForCancerTesting" Our Unique Approach PMI and Contextual Genomics

Strynadka, Natalie

236

Coral Reef Genomics: Developing tools for functional genomics of coral symbiosis  

E-Print Network [OSTI]

Coral Reef Genomics: Developing toolsfor functional genomics of coral symbiosis Jodi SCHWARZ 1 ,symbiosis functional genomics cDNA microarray ABSTRACT

Schwarz, Jodi; Brokstein, Peter; Manohar, Chitra; Coffroth, Mary Alice; Szmant, Alina; Medina, Monica

2008-01-01T23:59:59.000Z

237

GIS: a web-based genomics information system for efficiently manipulating and accessing genome physical maps.  

E-Print Network [OSTI]

??Biological science has entered the genome era. Global genome integrative physical and genetic mapping promises to revolutionize modern genomics research. To facilitate manipulation and applications… (more)

Chen, Huaming

2012-01-01T23:59:59.000Z

238

Navigating protected genomics data with UCSC Genome Browser in a Box.  

E-Print Network [OSTI]

H. et al. (2013) Integrative Genomics Viewer (IGV):High-performance genomics data visualization andbrowsers for comparative genomics. Bioinformatics. In press.

2014-01-01T23:59:59.000Z

239

Genomic Signal Processing: From Matrix Algebra to Genetic Networks  

E-Print Network [OSTI]

microarrays make it possible, for the first time, to record the complete genomic sig- nals that guide. These models are illustrated in the analyses of RNA expression data from yeast and human during their cell cycle programs and DNA-binding data from yeast cell cycle transcription factors and replication

Utah, University of

240

Genome Science/Technologies  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

student working with Armand Dichosa, Cliff Han and Krista Reitenga. She spends the bulk of her time on projects utilizing gel microdroplet technology. Armand Dichosa, PhD,...

Note: This page contains sample records for the topic "human genome project" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


241

A Collection of Algal Genomes from the JGI  

SciTech Connect (OSTI)

Algae, defined as photosynthetic eukaryotes other than plants, constitute a major component of fundamental eukaryotic diversity. Acquisition of the ability to conduct oxygenic photosynthesis through endosymbiotic events has been a principal driver of eukaryotic evolution, and today algae continue to underpin aquatic food chains as primary producers. Algae play profound roles in the carbon cycle, can impose health and economic costs through toxic blooms, and are candidate sources for bio-fuels; all of these research areas are part of the mission of DOE?s Joint Genome Institute (JGI). A collection of algal projects ongoing at JGI contributes to each of these areas and illustrates analyses employed in their genome exploration.

Kuo, Alan; Grigoriev, Igor

2012-03-19T23:59:59.000Z

242

Final project report  

SciTech Connect (OSTI)

The proposed overarching goal for this project was the following: Data integration, simulation and visualization will facilitate metabolic and regulatory network prediction, exploration, and formulation of hypotheses. We stated three specific aims to achieve the overarching goal of this project: (1) Integration of multiple levels of information such as mRNA and protein levels, predicted protein-protein interactions/associations and gene function will enable construction of models describing environmental response and dynamic behavior. (2) Flexible tools for network inference will accelerate our understanding of biological systems. (3) Flexible exploration and queries of model hypotheses will provide focus and reveal novel dependencies. The underlying philosophy of these proposed aims is that an iterative cycle of experiments, experimental design, and verification will lead to a comprehensive and predictive model that will shed light on systems level mechanisms involved in responses elicited by living systems upon sensing a change in their environment. In the previous years report we demonstrated considerable progress in development of data standards, regulatory network inference and data visualization and exploration. We are pleased to report that several manuscripts describing these procedures have been published in top international peer reviewed journals including Genome Biology, PNAS, and Cell. The abstracts of these manuscripts are given and they summarize our accomplishments in this project.

Nitin S. Baliga and Leroy Hood

2008-11-12T23:59:59.000Z

243

Project Construction  

Broader source: Energy.gov [DOE]

Integrating renewable energy into Federal new construction or major renovations requires effective structuring of the construction team and project schedule. This overview discusses key construction team considerations for renewable energy as well as timing and expectations for the construction phase. The project construction phase begins after a project is completely designed and the construction documents (100%) have been issued. Construction team skills and experience with renewable energy technologies are crucial during construction, as is how the integration of renewable energy affects the project construction schedule.

244

Magnesium Projects  

Broader source: Energy.gov (indexed) [DOE]

cyberinfrastructure projects and will be augmented by original research in Computer Science and Software Engineering towards the creation of large, distributed, autonomic and...

245

Salt Stress in Desulfovibrio vulgaris Hildenborough: An integrated genomics approach  

E-Print Network [OSTI]

2002. Integrating cancer genomics and proteomics in theWeb site for comparative genomics. Genome Res 15:1015-22.Hildenborough: An integrated genomics approach. Aindrila

Mukhopadhyay, Aindrila

2010-01-01T23:59:59.000Z

246

Computational methods and analyses in comparative genomics and epigenomics  

E-Print Network [OSTI]

promise of comparative genomics in mammals. Science, 286,homology relationships. Genomics, Dehal, P. and Boore, J.to plant comparative genomics. Genome Research, 13(5), 999–

Peng, Qian

2012-01-01T23:59:59.000Z

247

acanthamoeba castellanii genome: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

and Medicine Websites Summary: Prokaryotic Genomes Eurkaryotic Genomes Chapter 6. Genomics and Gene Identification Weigang Qiu Weigang Qiu Chapter 6. Genomics and Gene...

248

aeromonas caviae genomic: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

and Medicine Websites Summary: Prokaryotic Genomes Eurkaryotic Genomes Chapter 6. Genomics and Gene Identification Weigang Qiu Weigang Qiu Chapter 6. Genomics and Gene...

249

Population genomics: Whole-genome analysis of polymorphism and divergence in Drosophila simulans  

E-Print Network [OSTI]

PLoS BIOLOGY Population Genomics: Whole-Genome Analysis ofwww.plosbiology.org Population Genomics of D. simulans Table11 | e310 Population Genomics of D. simulans Table S15. GO

2007-01-01T23:59:59.000Z

250

POSTDOCTORAL POSITION IN BIOINFORMATICS AND EVOLUTIONARY GENOMICS: Next generation sequencing and analysis of complex polyploid genomes  

E-Print Network [OSTI]

POSTDOCTORAL POSITION IN BIOINFORMATICS AND EVOLUTIONARY GENOMICS: Next generation sequencing and analysis of complex polyploid genomes The research group Genome Evolution and Speciation (Team) to work on the analysis of genome and transcriptome sequence data (generated using 454 Roche

Rennes, Université de

251

GIS: a web-based genomics information system for efficiently manipulating and accessing genome physical maps  

E-Print Network [OSTI]

Biological science has entered the genome era. Global genome integrative physical and genetic mapping promises to revolutionize modern genomics research. To facilitate manipulation and applications of the results from genomics research, many...

Chen, Huaming

2000-01-01T23:59:59.000Z

252

Original article Neisseria Base: a comparative genomics  

E-Print Network [OSTI]

Original article Neisseria Base: a comparative genomics database for Neisseria meningitidis Lee S, septicemia and in some cases pneumonia. Genomic studies hold great promise for N. meningitidis research genomics database and genome browser that houses and displays publicly available N. meningitidis genomes

Jordan, King

253

A Novel Approach for Comparative Genomics  

E-Print Network [OSTI]

A Novel Approach for Comparative Genomics & Annotation Transfer Alban MANCHERON Raluca URICARU Eric is genome comparison good for?" Genome comparison is crucial for genome annotation, regulatory motifs identification, and vaccine design aims at finding genomic regions either specific to or in one

Paris-Sud XI, Université de

254

Evolutionary Genomics of Prokaryotic Viruses.  

E-Print Network [OSTI]

??Evolutionary history of biological entities is recorded within their nucleic acid sequences and can (sometimes) be deciphered by thorough genomic analysis. In this study we… (more)

Krupovic, Mart

2010-01-01T23:59:59.000Z

255

Comparative genomics of arabidopsis thaliana.  

E-Print Network [OSTI]

??The highly sel?ng Arabidopsis thaliana differs from its closest relative, the obligate outcrosser A. lyrata, both in genome size and organization. During approximately 5 million… (more)

Hu, Tina T.

2009-01-01T23:59:59.000Z

256

Genomics Division Home  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation ProposedUsingFun with Big Sky Learning Fun withGenepoolCrystals.Genomefor Genomics DanPIs Mark

257

Genomics and Systems Biology  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation ProposedUsingFun with Big Sky Learning Fun withGenepoolCrystals.Genomefor Genomics DanPIs

258

Integrative Genomics Building  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation ProposedUsingFunInfrared Land SurfaceVirus-Infected MacaquesIntegration ofIntegrative Genomics

259

Yeast Genomic Library Genomic DNA Sau3AI partial digestion  

E-Print Network [OSTI]

Yeast Genomic Library Concept: Genomic DNA ­ Sau3AI partial digestion Vector DNA ­ BamHI full digestion partial Ligate and transform above products Vector Information: · use centromeric plasmid to avoid of the mcs Preparing Vector: 1) digest 3-4ug of library vector with BamHI for 2-4hrs in a total volume of 20

Odorizzi, Greg

260

Trichoderma: the genomics of opportunistic success  

E-Print Network [OSTI]

of a fungal prey. BMC Genomics 10, 567 (2009). This studythe TrichoEST functional genomics approach. Curr. Genet. 51,in Hypocrea jecorina. BMC Genomics. 9, 430 (2008) Mukherjee,

Druzhinina, Irina S.

2011-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "human genome project" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


261

Evolutionary Genomics of Salmonella enterica Subspecies  

E-Print Network [OSTI]

M. 2002. Evolutionary genomics of Salmonella: genesubsystems technology. BMC Genomics 9:75. 23. Ochman H,Salmonella enterica. BMC Genomics 12:425. PubMed. 29. Falush

2013-01-01T23:59:59.000Z

262

Tissue sampling and standards for vertebrate genomics  

E-Print Network [OSTI]

and standards for vertebrate genomics. GigaScience 2012 1:8.transition to conservation genomics. TIG 2010, 26:177–187.Siemens DH: Ecological genomics––changing perspectives on

2012-01-01T23:59:59.000Z

263

E-Print Network 3.0 - adult human keratinocytes Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

of Washington at Seattle Collection: Chemistry ; Biology and Medicine 28 Genome-wide comparison of human keratinocyte and squamous cell carcinoma responses to UVB irradiation:...

264

[New hosts and vectors for genome cloning]. Progress report  

SciTech Connect (OSTI)

The main goal of our project remains the development of new bacterial hosts and vectors for the stable propagation of human DNA clones in E. coli. During the past six months of our current budget period, we have (1) continued to develop new hosts that permit the stable maintenance of unstable features of human DNA, and (2) developed a series of vectors for (a) cloning large DNA inserts, (b) assessing the frequency of human sequences that are lethal to the growth of E. coli, and (c) assessing the stability of human sequences cloned in M13 for large-scale sequencing projects.

Not Available

1991-12-31T23:59:59.000Z

265

Project X  

E-Print Network [OSTI]

provided by Project X would be a cost- effective approach toin Section I and for the cost estimate necessary as part ofby DOE order 413.3b. The cost range required for CD-0 will

Holmes, Steve

2014-01-01T23:59:59.000Z

266

Project Manager  

Broader source: Energy.gov [DOE]

A successful candidate in this position will serve as a project manager in the Fuel Cell Technologies Office in the DOE-EERE Office of Transportation responsible for a wide variety of highly...

267

Project Title:  

Broader source: Energy.gov (indexed) [DOE]

0 181 0 Hazardous Air Pollutants? Is the project subject to emissions limitations in an Air Quality 0 181 0 Control Region? 2 Revised on: 11122008 NEPA COMPLIANCE SURVEY Impacts...

268

COMMENTARY Open Access Crowdfunding the Azolla fern genome project  

E-Print Network [OSTI]

that allows the public to participate in, as well as to support and witness advancements in science. Here we for sustainable agriculture, phytoremediation and biofuel production. Azolla is more than just a fern

269

FCTO Projects and the Materials Genome Initiative Webinar  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

2014 Fall MRS Meeting Targeting a 2x acceleration of the materials-to-market process 5 | Fuel Cell Technologies Office eere.energy.gov Four Key MGI Challenges* (1) Leading a...

270

FCTO Projects and the Materials Genome Initiative Webinar  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:YearRound-UpHeat PumpRecord ofESPCofConstruction Management FAQSSafetyofBG-PLN-0036 Rev. 6FCEVs

271

USDA and DOE Fund Genomics Projects For Bioenergy Fuels Research |  

Broader source: Energy.gov (indexed) [DOE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "ofEarly Career Scientists' Research Petroleum ReserveDepartment of Energy AtNoticeMotorThis8,Production

272

Comparative genomics of the Mycobacterium tuberculosis complex.  

E-Print Network [OSTI]

??The study of microbial evolution has been recently accelerated by the advent of comparative genomics, an approach enabling investigation of organisms at the whole-genome level.… (more)

Mostowy, Serge.

2005-01-01T23:59:59.000Z

273

Joint Genome Institute Progress Report 2002-2005  

E-Print Network [OSTI]

for international plant science. CSP PORTFOLIO 2005 ProjectsCSP in 2004 for sequencing in 2005 represented a rich collection of microorganisms; higher plantsplant that may be beneficial for human health and agriculture. Additional 2005 CSP

Gilbert, David

2005-01-01T23:59:59.000Z

274

Flash Updates of GSC projects (GSC8 Meeting)  

ScienceCinema (OSTI)

The Genomic Standards Consortium was formed in September 2005. It is an international, open-membership working body which promotes standardization in the description of genomes and the exchange and integration of genomic data. The 2009 meeting was an activity of a five-year funding Research Coordination Network from the National Science Foundation and was organized held at the DOE Joint Genome Institute with organizational support provided by the JGI and by the University of California - San Diego. In quick succession Frank Oliver Glockner (MPI-Bremen), Victor Markowitz (LBNL), Nikos Kyripides (JGI), Folker Meyer (ANL), Linda Amaral-Zettler (Marine Biology Lab), and James Cole (Michigan State University) provide updates on a number of topics related to GSC projects at the Genomic Standards Consortium 8th meeting at the DOE JGI in Walnut Creek, Calif. on Sept. 9, 2009.

Glockner, Frank Oliver; Markowitz, Victor; Kyrpides, Nikos; Meyer, Folker; Amaral-Zettler, Linda; Cole, James

2011-04-29T23:59:59.000Z

275

Project Fact Sheet Project Update  

E-Print Network [OSTI]

medical and dental centre; shop and café area for students and vacation accommodation centre. The new & Figures: Budget: £51,074,000 Funding Source: Capital Plan Construction Project Programme: Start on Site

276

Human Health Science Building Geothermal Heat Pumps | Department...  

Broader source: Energy.gov (indexed) [DOE]

Human Health Science Building Geothermal Heat Pumps Human Health Science Building Geothermal Heat Pumps Project objectives: Construct a ground sourced heat pump, heating,...

277

Intra-species sequence comparisons for annotating genomes  

SciTech Connect (OSTI)

Analysis of sequence variation among members of a single species offers a potential approach to identify functional DNA elements responsible for biological features unique to that species. Due to its high rate of allelic polymorphism and ease of genetic manipulability, we chose the sea squirt, Ciona intestinalis, to explore intra-species sequence comparisons for genome annotation. A large number of C. intestinalis specimens were collected from four continents and a set of genomic intervals amplified, resequenced and analyzed to determine the mutation rates at each nucleotide in the sequence. We found that regions with low mutation rates efficiently demarcated functionally constrained sequences: these include a set of noncoding elements, which we showed in C intestinalis transgenic assays to act as tissue-specific enhancers, as well as the location of coding sequences. This illustrates that comparisons of multiple members of a species can be used for genome annotation, suggesting a path for the annotation of the sequenced genomes of organisms occupying uncharacterized phylogenetic branches of the animal kingdom and raises the possibility that the resequencing of a large number of Homo sapiens individuals might be used to annotate the human genome and identify sequences defining traits unique to our species. The sequence data from this study has been submitted to GenBank under accession nos. AY667278-AY667407.

Boffelli, Dario; Weer, Claire V.; Weng, Li; Lewis, Keith D.; Shoukry, Malak I.; Pachter, Lior; Keys, David N.; Rubin, Edward M.

2004-07-15T23:59:59.000Z

278

Project Final Report UBC LBS Project Services1 Project Final Report UBC LBS Project Services2  

E-Print Network [OSTI]

Project Final Report UBC LBS Project Services1 #12;Project Final Report UBC LBS Project Services2 EXECUTIVE SUMMARY The purpose of the UBC Project Services web-based project management portal project on campus within Project Services, and with the rest of the UBC community. We began this project by defining

279

Complete Genome Sequence of Yersinia pestis Strains Antiqua and Nepal516: Evidence of Gene Reduction in an Emerging Pathogen  

E-Print Network [OSTI]

a human infection in Nepal (possibly from a 1967 outbreak ofone IS285 in CO92, KIM and Nepal but not Antiqua; and oneLoss of functional TufB in Nepal The genomes of Y. pestis

2006-01-01T23:59:59.000Z

280

Hanford Environmental Dose Reconstruction Project  

SciTech Connect (OSTI)

The objective of the Hanford Environmental Dose Reconstruction Project is to estimate the radiation doses that individuals and populations could have received from nuclear operations at Hanford since 1944. The project is being managed and conducted by the Battelle Pacific Northwest Laboratories under contract with the Centers for Disease Control. The independent Technical Steering Panel (TSP) provides technical direction. The project is divided into the following technical tasks. These tasks correspond to the path radionuclides followed, from release to impact on humans (dose estimates): source terms; environmental transport; environmental monitoring data; demography, food consumption, and agriculture; environmental pathways and dose estimates.

Finch, S.M.; McMakin, A.H. (comps.)

1992-06-01T23:59:59.000Z

Note: This page contains sample records for the topic "human genome project" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


281

Cloudnet Project  

DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

Cloudnet is a research project supported by the European Commission. This project aims to use data obtained quasi-continuously for the development and implementation of cloud remote sensing synergy algorithms. The use of active instruments (lidar and radar) results in detailed vertical profiles of important cloud parameters which cannot be derived from current satellite sensing techniques. A network of three already existing cloud remote sensing stations (CRS-stations) will be operated for a two year period, activities will be co-ordinated, data formats harmonised and analysis of the data performed to evaluate the representation of clouds in four major european weather forecast models.

Hogan, Robin

282

Genome-Wide Identification and 3D Modeling of Proteins involved in DNA Damage Recognition and Repair (Final Report)  

SciTech Connect (OSTI)

OAK-B135 DNA Damage Recognition and Repair (DDR and R) proteins play a critical role in cellular responses to low-dose radiation and are associated with cancer. the authors have performed a systematic, genome-wide computational analysis of genomic data for human genes involved in the DDR and R process. The significant achievements of this project include: (1) Construction of the computational pipeline for searching DDR and R genes, building and validation of 3D models of proteins involved in DDR and R; (2) Functional and structural annotation of the 3D models and generation of comprehensive lists of suggested knock-out mutations; (3) Important improvement of macromolecular docking technology and its application to predict the DNA-Protein complex conformation; (4) Development of a new algorithm for improved analysis of high-density oligonucleotide arrays for gene expression profiling; (5) Construction and maintenance of the DNA Damage Recognition and Repair Database; and (6) Producing 14 research papers (10 published and 4 in preparation).

Ruben A. Abagyan, PhD

2004-04-15T23:59:59.000Z

283

Challenges in Whole-Genome Annotation of Pyrosequenced Eukaryotic Genomes  

SciTech Connect (OSTI)

Pyrosequencing technologies such as 454/Roche and Solexa/Illumina vastly lower the cost of nucleotide sequencing compared to the traditional Sanger method, and thus promise to greatly expand the number of sequenced eukaryotic genomes. However, the new technologies also bring new challenges such as shorter reads and new kinds and higher rates of sequencing errors, which complicate genome assembly and gene prediction. At JGI we are deploying 454 technology for the sequencing and assembly of ever-larger eukaryotic genomes. Here we describe our first whole-genome annotation of a purely 454-sequenced fungal genome that is larger than a yeast (>30 Mbp). The pezizomycotine (filamentous ascomycote) Aspergillus carbonarius belongs to the Aspergillus section Nigri species complex, members of which are significant as platforms for bioenergy and bioindustrial technology, as members of soil microbial communities and players in the global carbon cycle, and as agricultural toxigens. Application of a modified version of the standard JGI Annotation Pipeline has so far predicted ~;;10k genes. ~;;12percent of these preliminary annotations suffer a potential frameshift error, which is somewhat higher than the ~;;9percent rate in the Sanger-sequenced and conventionally assembled and annotated genome of fellow Aspergillus section Nigri member A. niger. Also,>90percent of A. niger genes have potential homologs in the A. carbonarius preliminary annotation. Weconclude, and with further annotation and comparative analysis expect to confirm, that 454 sequencing strategies provide a promising substrate for annotation of modestly sized eukaryotic genomes. We will also present results of annotation of a number of other pyrosequenced fungal genomes of bioenergy interest.

Kuo, Alan; Grigoriev, Igor

2009-04-17T23:59:59.000Z

284

SHORT REVIEW Ecological genomics: understanding gene and  

E-Print Network [OSTI]

SHORT REVIEW Ecological genomics: understanding gene and genome function in the natural environment MC Ungerer, LC Johnson and MA Herman Division of Biology, Ecological Genomics Institute, Kansas State University, Manhattan, KS, USA The field of ecological genomics seeks to understand the genetic mechanisms

Kaufman, Glennis A.

285

Hindawi Publishing Corporation Comparative and Functional Genomics  

E-Print Network [OSTI]

Hindawi Publishing Corporation Comparative and Functional Genomics Volume 2007, Article ID 47304, 7 pages doi:10.1155/2007/47304 Meeting Report eGenomics: Cataloguing Our Complete Genome Collection III, Michigan State University, East Lansing, MI 48824, USA 3 The Institute for Genomic Research, 9712 Medical

Newcastle upon Tyne, University of

286

A Statistical Framework for Spatial Comparative Genomics  

E-Print Network [OSTI]

A Statistical Framework for Spatial Comparative Genomics Rose Hoberman May 2007 CMU-CS-07, or the U.S. Government. #12;Keywords: spatial comparative genomics, comparative genomics, gene clusters, max-gap clusters, gene teams, whole genome duplication, paralogons, synteny, ortholog detection #12

287

Genomics and ornithology Scott V. Edwards  

E-Print Network [OSTI]

REVIEW Genomics and ornithology Scott V. Edwards Received: 23 September 2007 / Accepted: 27 Genomics is revolutionizing ornithology in the same ways it is reinvigorating other biological disciplines. In this review, I will highlight applications of genomics and genomics technologies to the study of the ecology

Edwards, Scott

288

Genomic Aspects of Research Involving Polyploid Plants  

SciTech Connect (OSTI)

Almost all extant plant species have spontaneously doubled their genomes at least once in their evolutionary histories, resulting in polyploidy which provided a rich genomic resource for evolutionary processes. Moreover, superior polyploid clones have been created during the process of crop domestication. Polyploid plants generated by evolutionary processes and/or crop domestication have been the intentional or serendipitous focus of research dealing with the dynamics and consequences of genome evolution. One of the new trends in genomics research is to create synthetic polyploid plants which provide materials for studying the initial genomic changes/responses immediately after polyploid formation. Polyploid plants are also used in functional genomics research to study gene expression in a complex genomic background. In this review, we summarize the recent progress in genomics research involving ancient, young, and synthetic polyploid plants, with a focus on genome size evolution, genomics diversity, genomic rearrangement, genetic and epigenetic changes in duplicated genes, gene discovery, and comparative genomics. Implications on plant sciences including evolution, functional genomics, and plant breeding are presented. It is anticipated that polyploids will be a regular subject of genomics research in the foreseeable future as the rapid advances in DNA sequencing technology create unprecedented opportunities for discovering and monitoring genomic and transcriptomic changes in polyploid plants. The fast accumulation of knowledge on polyploid formation, maintenance, and divergence at whole-genome and subgenome levels will not only help plant biologists understand how plants have evolved and diversified, but also assist plant breeders in designing new strategies for crop improvement.

Yang, Xiaohan [ORNL; Ye, Chuyu [ORNL; Tschaplinski, Timothy J [ORNL; Wullschleger, Stan D [ORNL; Tuskan, Gerald A [ORNL

2011-01-01T23:59:59.000Z

289

PROJECT REQUEST FORM PROJECT HOLDER INFORMATION  

E-Print Network [OSTI]

PROJECT REQUEST FORM Last Name: Email: PROJECT HOLDER INFORMATION UCID:Last Name: Email: Institute if different than Project Holder) First Name: Project Short Name: (50 characters max) (for eFIN view only) Project Title: PROJECT INFORMATION Start Date (MM/DD/YYYY): End Date (MM/DD/YYYY): For Questions or HELP

de Leon, Alex R.

290

Methods in comparative genomics: genome correspondence, gene identification and motif discovery  

E-Print Network [OSTI]

1 Methods in comparative genomics: genome correspondence, gene identification and motif discovery@mit.edu, nickp@genome.wi.mit.edu, bwb@genome.wi.mit.edu, bab@mit.edu, lander@wi.mit.edu (1) MIT/Whitehead Institute Center for Genome Research, 320 Charles St., Cambridge MA 02139 (2) MIT Computer Science

Kellis, Manolis

291

Synthetic Genomics: Options for Governance  

E-Print Network [OSTI]

Gene and genome synthesis, that is, constructing long stretches of DNA from constituent chemicals, provides scientists with new and unparalleled capabilities both for understanding biology and for using it for beneficial ...

Garfinkel, Michele

2007-10-17T23:59:59.000Z

292

Project Fact Sheet Project Brief  

E-Print Network [OSTI]

Name: Centre for Assisted Robotic Surgery Number: BESS1002b Project Champion: Professor Guang-Zong Yang of the refurbishment is to renew and expand the laboratory space for Robotic Assisted Surgery at the South Kensington Campus as par to the Hamlyn Centre for Robotic Surgery. The overall programme incorpo- rates both core

293

E-Print Network 3.0 - analyses genomes comparison Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

genomes comparison Page: << < 1 2 3 4 5 > >> 1 A Novel Approach for Comparative Genomics Summary: is genome comparison good for?" Genome comparison is crucial for genome...

294

Implications of structural genomics target selection strategies: Pfam5000, whole genome, and random approaches  

E-Print Network [OSTI]

SK, Bonanno JB. Structural genomics. Methods Biochem AnalMizuguchi K. Structural genomics: an overview. Prog BiophysSE. A tour of structural genomics. Nat Rev Genet 2001;2(10):

Chandonia, John-Marc; Brenner, Steven E.

2004-01-01T23:59:59.000Z

295

Independence) PROJECT TITLE: Clinton Community Human Service...  

Broader source: Energy.gov (indexed) [DOE]

between the borefield and the building would circulate water through High DenSity Polyethylene (HOPE) piping. The boreholes would be entirely encased with thermally enhanced...

296

Dissection of Plant Defense Mechanisms Using Chemical and Molecular Genomics  

E-Print Network [OSTI]

of auxins by a chemical genomics approach." Journal ofadvances in chemical genomics." Current Medicinal Chemistrymolecular and chemical genomics." Phytopathology 97(7): S58-

Rodriguez-Salus, Melinda Sue

2012-01-01T23:59:59.000Z

297

Comparative genomics reveals diversity among xanthomonads infecting tomato and pepper  

E-Print Network [OSTI]

Potnis et al. : Comparative genomics reveals diversity amongtomato and pepper. BMC Genomics Submit your next manuscriptpv. syringae Potnis et al. BMC Genomics 2011, 12:146 http://

2011-01-01T23:59:59.000Z

298

Incorporating Genomics and Bioinformatics across the Life Sciences Curriculum  

E-Print Network [OSTI]

Page Incorporating Genomics and Bioinformatics across the2007) Discovering Genomics, Proteomics, and Bioinformatics,2003) Public access for teaching genomics, proteomics, and

Ditty, Jayna L.

2012-01-01T23:59:59.000Z

299

TOPSAN: a collaborative annotation environment for structural genomics.  

E-Print Network [OSTI]

environment for structural genomics Dana Weekes 1† , S Srihigh-throughput structural genomics centers, despite theirbeing determined by structural genomics centers and high-

Weekes, Dana; Krishna, S; Bakolitsa, Constantina; Wilson, Ian A; Godzik, Adam; Wooley, John

2010-01-01T23:59:59.000Z

300

Validation in Genomics: CpG Island Methylation Revisited  

E-Print Network [OSTI]

analysis. In: Functional Genomics: Methods and Protocols, M.Segal: Validation in Genomics: CpG Island Methylationpackage and applications to genomics. Bioinformatics and

Segal, Mark R

2006-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "human genome project" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


301

Environmental Genomics Reveals a Single-Species Ecosystem Deep Earth  

E-Print Network [OSTI]

Environmental Genomics Reveals a Single-Species EcosystemTechnology Program, DOE Joint Genomics Institute, Berkeley,and Environmental Research, Genomics:GTL program through

Arkin, Adam P.

2014-01-01T23:59:59.000Z

302

MicrobesOnline: an integrated portal for comparative functional genomics  

E-Print Network [OSTI]

comparative functional genomics Marcin P. Joachimiak 1,2 ,for comparative functional genomics of bacteria and archaea.publicly avail- able functional genomics data from published

Joachimiak, Marcin P.

2014-01-01T23:59:59.000Z

303

Microbes Online: an integrated portal for comparative functional genomics  

E-Print Network [OSTI]

comparative functional genomics of bacteria, archaea, fungifor comparative functional genomics Paramvir S. Dehal 1,2* (and Environmental Research, Genomics:GTL program through

Arkin, Adam P.

2014-01-01T23:59:59.000Z

304

Complete genome sequence of Desulfomicrobium baculatum type strain (XT)  

SciTech Connect (OSTI)

Desulfomicrobium baculatum is the type species of the genus Desulfomicrobium, which is the type genus of the family Desulfomicrobiaceae. It is of phylogenetic interest because of the isolated location of the family Desulfomicrobiaceae within the order Desulfovibrionales. D. baculatum strain XT is a Gram-negative, motile, sulfate-reducing bacterium isolated from water-saturated manganese carbonate ore. It is strictly anaerobic and does not require NaCl for growth, although NaCl concentrations up to 6percent (w/v) are tolerated. The metabolism is respiratory or fermentative. In the presence of sulfate, pyruvate and lactate are incompletely oxidized to acetate and CO2. Here we describe the features of this organism, together with the complete genome sequence and annotation. This is the first completed genome sequence of a member of the deltaproteobacterial family Desulfomicrobiaceae, and this 3,942,657 bp long single replicon genome with its 3494 protein-coding and 72 RNA genes is part of the Genomic Encyclopedia of Bacteria and Archaea project.

Copeland, Alex; Spring, Stefan; Goker, Markus; Schneider, Susanne; Lapidus, Alla; Glavina Del Rio, Tijana; Tice, Hope; Cheng, Jan-Fang; Lucas, Susan; Chen, Feng; Nolan, Matt; Bruce, David; Goodwin, Lynne; Pitluck, Sam; Ivanova, Natalia; Mavrommatis, Konstantinos; Ovchinnikova, Galina; Pati, Amrita; Chen, Amy; Palaniappan, Krishna; Land, Miriam; Hauser, Loren; Chang, Yun-Juan; Jefferies, Cynthia C; Meincke, Linda; Sims, David; Brettin, Thomas; Detter, John C; Han, Cliff; Chain, Patrick; Bristow, James; Eisen, Jonathan; Markowitz, Victor; Hugenholtz, Philip; Klenk, Hans-Peter; Kyrpides, Nikos C; Lucas, Susan

2009-05-20T23:59:59.000Z

305

Complete genome sequence of Actinosynnema mirum type strain (101T)  

SciTech Connect (OSTI)

Actinosynnema mirum Hasegawa et al. 1978 is the type species of the genus, and is of phylogenetic interest because of its central phylogenetic location in the Actino-synnemataceae, a rapidly growing family within the actinobacterial suborder Pseudo-nocardineae. A. mirum is characterized by its motile spores borne on synnemata and as a producer of nocardicin antibiotics. It is capable of growing aerobically and under a moderate CO2 atmosphere. The strain is a Gram-positive, aerial and substrate mycelium producing bacterium, originally isolated from a grass blade collected from the Raritan River, New Jersey. Here we describe the features of this organism, together with the complete genome sequence and annotation. This is the first complete genome sequence of a member of the family Actinosynnemataceae, and only the second sequence from the actinobacterial suborder Pseudonocardineae. The 8,248,144 bp long single replicon genome with its 7100 protein-coding and 77 RNA genes is part of the Genomic Encyclopedia of Bacteria and Archaea project.

Land, Miriam L [ORNL; Lapidus, Alla L. [U.S. Department of Energy, Joint Genome Institute; Mayilraj, Shanmugam [DSMZ - German Collection of Microorganisms and Cell Cultures GmbH, Braunschweig, Germany; Chen, Feng [U.S. Department of Energy, Joint Genome Institute; Copeland, A [U.S. Department of Energy, Joint Genome Institute; Glavina Del Rio, Tijana [U.S. Department of Energy, Joint Genome Institute; Nolan, Matt [U.S. Department of Energy, Joint Genome Institute; Lucas, Susan [U.S. Department of Energy, Joint Genome Institute; Tice, Hope [U.S. Department of Energy, Joint Genome Institute; Cheng, Jan-Fang [U.S. Department of Energy, Joint Genome Institute; Chertkov, Olga [Los Alamos National Laboratory (LANL); Bruce, David [U.S. Department of Energy, Joint Genome Institute; Goodwin, Lynne A. [Los Alamos National Laboratory (LANL); Pitluck, Sam [U.S. Department of Energy, Joint Genome Institute; Rohde, Manfred [HZI - Helmholtz Centre for Infection Research, Braunschweig, Germany; Goker, Markus [DSMZ - German Collection of Microorganisms and Cell Cultures GmbH, Braunschweig, Germany; Pati, Amrita [U.S. Department of Energy, Joint Genome Institute; Ivanova, N [U.S. Department of Energy, Joint Genome Institute; Mavromatis, K [U.S. Department of Energy, Joint Genome Institute; Chen, Amy [U.S. Department of Energy, Joint Genome Institute; Palaniappan, Krishna [U.S. Department of Energy, Joint Genome Institute; Hauser, Loren John [ORNL; Chang, Yun-Juan [ORNL; Jeffries, Cynthia [Oak Ridge National Laboratory (ORNL); Brettin, Thomas S [ORNL; Detter, J. Chris [U.S. Department of Energy, Joint Genome Institute; Han, Cliff [Los Alamos National Laboratory (LANL); Chain, Patrick S. G. [Lawrence Livermore National Laboratory (LLNL); Tindall, Brian [DSMZ - German Collection of Microorganisms and Cell Cultures GmbH, Braunschweig, Germany; Bristow, James [U.S. Department of Energy, Joint Genome Institute; Eisen, Jonathan [U.S. Department of Energy, Joint Genome Institute; Markowitz, Victor [U.S. Department of Energy, Joint Genome Institute; Hugenholtz, Philip [U.S. Department of Energy, Joint Genome Institute; Kyrpides, Nikos C [U.S. Department of Energy, Joint Genome Institute; Klenk, Hans-Peter [DSMZ - German Collection of Microorganisms and Cell Cultures GmbH, Braunschweig, Germany

2009-01-01T23:59:59.000Z

306

Complete genome sequence of Actinosynnema mirum type strain (101T)  

SciTech Connect (OSTI)

Actinosynnema mirum Hasegawa et al. 1978 is the type species of the genus, and is of phylogenetic interest because of its central phylogenetic location in the Actino-synnemataceae, a rapidly growing family within the actinobacterial suborder Pseudo-nocardineae. A. mirum is characterized by its motile spores borne on synnemata and as a producer of nocardicin antibiotics. It is capable of growing aerobically and under a moderate CO2 atmosphere. The strain is a Gram-positive, aerial and substrate mycelium producing bacterium, originally isolated from a grass blade collected from the Raritan River, New Jersey. Here we describe the features of this organism, together with the complete genome sequence and annotation. This is the first complete genome sequence of a member of the family Actinosynnemataceae, and only the second sequence from the actinobacterial suborder Pseudonocardineae. The 8,248,144 bp long single replicon genome with its 7100 protein-coding and 77 RNA genes is part of the Genomic Encyclopedia of Bacteria and Archaea project.

Land, Miriam; Lapidus, Alla; Mayilraj, Shanmugam; Chen, Feng; Copeland, Alex; Glavina Del Rio, Tijana; Nolan, Matt; Lucas, Susan; Tice, Hope; Cheng, Jan-Fang; Chertkov, Olga; Bruce, David; Goodwin, Lynne; Pitluck, Sam; Rohde, Manfred; Goker, Markus; Pati, Amrita; Ivanova, Natalia; Mavrommatis, Konstantinos; Chen, Amy; Palaniappan, Krishna; Hauser, Loren; Chang, Yun-Juan; Jefferies, Cynthia; Brettin, Thomas; Detter, John C.; Han, Cliff; Chain, Patrick; Tindall, Brian; Bristow, James; Eisen, Jonathan A.; Markowitz, Victor; Hugenholtz, Philip; Kyrpides, Nikos C.; Klenk, Hans-Peter

2009-05-20T23:59:59.000Z

307

Reconstruction of a Bacterial Genome from DNA Cassettes  

SciTech Connect (OSTI)

This basic research program comprised two major areas: (1) acquisition and analysis of marine microbial metagenomic data and development of genomic analysis tools for broad, external community use; (2) development of a minimal bacterial genome. Our Marine Metagenomic Diversity effort generated and analyzed shotgun sequencing data from microbial communities sampled from over 250 sites around the world. About 40% of the 26 Gbp of sequence data has been made publicly available to date with a complete release anticipated in six months. Our results and those mining the deposited data have revealed a vast diversity of genes coding for critical metabolic processes whose phylogenetic and geographic distributions will enable a deeper understanding of carbon and nutrient cycling, microbial ecology, and rapid rate evolutionary processes such as horizontal gene transfer by viruses and plasmids. A global assembly of the generated dataset resulted in a massive set (5Gbp) of genome fragments that provide context to the majority of the generated data that originated from uncultivated organisms. Our Synthetic Biology team has made significant progress towards the goal of synthesizing a minimal mycoplasma genome that will have all of the machinery for independent life. This project, once completed, will provide fundamentally new knowledge about requirements for microbial life and help to lay a basic research foundation for developing microbiological approaches to bioenergy.

Christopher Dupont; John Glass; Laura Sheahan; Shibu Yooseph; Lisa Zeigler Allen; Mathangi Thiagarajan; Andrew Allen; Robert Friedman; J. Craig Venter

2011-12-31T23:59:59.000Z

308

Proposed Start Date: Title of Project  

E-Print Network [OSTI]

Proposed Start Date: Title of Project: 1 Department:Principal Investigator(s): 1. College: Phone/ Email: 5 6 7 8 Does project involve: Human subjects? No Yes VertebrateAnimals? No Yes Radioactive understand and agree to comply with the URI policies and procedures for misconduct, conflict of interest

Rhode Island, University of

309

Human Health Science Building Geothermal Heat Pumps  

Broader source: Energy.gov (indexed) [DOE]

HUMAN HEALTH SCIENCE BLDG GEO HEAT PUMP SYSTEMS Principal Investigator Source Heat Pumps Demo Projects May 20, 2010 This presentation does not contain any proprietary confidential,...

310

Conservation of exon scrambling in human and mouse  

E-Print Network [OSTI]

Exon scrambling is a phenomenon in which the exons of an mRNA transcript are spliced in an order inconsistent with that of the genome. In this thesis, I present a computational analysis of scrambled exons in human and ...

Hamilton, Monica L. (Monica Lauren)

2012-01-01T23:59:59.000Z

311

Addressing the Omics Data Explosion: a Comprehensive Reference Genome Representation and the Democratization of Comparative Genomics and Immunogenomics  

E-Print Network [OSTI]

Hubs: Web Accessible Browsers for Compar- ative Genomics 3.1Comparative Genomics Analyses . . . . . . . . . . . . . .browsers for comparative genomics” B.1 E. coli KO11FL 162099

Nguyen, Ngan Kim

2014-01-01T23:59:59.000Z

312

Hallmark Project  

Broader source: Energy.gov (indexed) [DOE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "ofEarly Career Scientists'Montana.ProgramJulietip sheetK-4In 2013 many autoThis road map isofAOnOctoberProject

313

PROJECT SUMMARY  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious RankCombustion | Department ofT ib l L d F SSales LLCDieselEnergyHistoryWATER-ENERGYofPROJECT

314

Custom Projects  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation Proposed Newcatalyst phases onOrganization FY 2012 FY 2013 FYCurtailment DateCustom-Projects

315

Project Gnome  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear Security Administration the1 - SeptemberMicroneedles for4-16Hamada winsProgress ReportProject CostEnergy

316

Part II: Project Summaries Project Summaries  

E-Print Network [OSTI]

Part II: Project Summaries Part II Project Summaries #12 generally cannot be achieved for reasonable computational cost. Applications that require modeling, and in nondestructive testing. The objective of this project is to advance the state of the art in electromagnetic

Perkins, Richard A.

317

Complete genome sequence of Nakamurella multipartita type strain (Y-104T)  

SciTech Connect (OSTI)

Nakamurella multipartita (Yoshimi et al. 1996) Tao et al. 2004 is the type species of the small one-species genus Nakamurella in the actinomycetal suborder Frankineae. The nonmotile, coccus-shaped strain was isolated from activated sludge acclimated with sugar-containing synthetic wastewater, and is able of accumulating large amounts of polysaccharides in its cells. Here we describe the features of the organism, together with the complete genome sequence and annotation. This is the first complete genome sequence of a member of the family Nakamurellaceae. The 6,060,298 bp long single replicon genome with its 5415 protein-coding and 53 RNA genes is part of the Genomic Encyclopedia of Bacteria and Archaea project.

Tice, Hope [U.S. Department of Energy, Joint Genome Institute; Mayilraj, Shanmugam [DSMZ - German Collection of Microorganisms and Cell Cultures GmbH, Braunschweig, Germany; Sims, David [Los Alamos National Laboratory (LANL); Lapidus, Alla L. [U.S. Department of Energy, Joint Genome Institute; Nolan, Matt [U.S. Department of Energy, Joint Genome Institute; Lucas, Susan [U.S. Department of Energy, Joint Genome Institute; Glavina Del Rio, Tijana [U.S. Department of Energy, Joint Genome Institute; Copeland, A [U.S. Department of Energy, Joint Genome Institute; Cheng, Jan-Fang [U.S. Department of Energy, Joint Genome Institute; Meincke, Linda [Los Alamos National Laboratory (LANL); Bruce, David [Los Alamos National Laboratory (LANL); Goodwin, Lynne A. [Los Alamos National Laboratory (LANL); Pitluck, Sam [U.S. Department of Energy, Joint Genome Institute; Ivanova, N [U.S. Department of Energy, Joint Genome Institute; Mavromatis, K [U.S. Department of Energy, Joint Genome Institute; Ovchinnikova, Galina [U.S. Department of Energy, Joint Genome Institute; Pati, Amrita [U.S. Department of Energy, Joint Genome Institute; Chen, Amy [U.S. Department of Energy, Joint Genome Institute; Palaniappan, Krishna [U.S. Department of Energy, Joint Genome Institute; Land, Miriam L [ORNL; Hauser, Loren John [ORNL; Chang, Yun-Juan [ORNL; Jeffries, Cynthia [Oak Ridge National Laboratory (ORNL); Detter, J. Chris [U.S. Department of Energy, Joint Genome Institute; Rohde, Manfred [HZI - Helmholtz Centre for Infection Research, Braunschweig, Germany; Goker, Markus [DSMZ - German Collection of Microorganisms and Cell Cultures GmbH, Braunschweig, Germany; Bristow, James [U.S. Department of Energy, Joint Genome Institute; Eisen, Jonathan [U.S. Department of Energy, Joint Genome Institute; Markowitz, Victor [U.S. Department of Energy, Joint Genome Institute; Hugenholtz, Philip [U.S. Department of Energy, Joint Genome Institute; Kyrpides, Nikos C [U.S. Department of Energy, Joint Genome Institute; Klenk, Hans-Peter [DSMZ - German Collection of Microorganisms and Cell Cultures GmbH, Braunschweig, Germany; Chen, Feng [U.S. Department of Energy, Joint Genome Institute

2010-01-01T23:59:59.000Z

318

Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21T)  

SciTech Connect (OSTI)

Stackebrandtia nassauensis Labeda and Kroppenstedt (2005) is the type species of the genus Stackebrandtia, and a member of the actinobacterial family Glycomycetaceae. Strackebrandtia currently contains two species, which are differentiated from Glycomyces spp. by cellular fatty acid and menaquinone composition. Strain LLR-40K-21T is Gram-positive, aerobic, and nonmotile, with a branched substrate mycelium and on some media an aerial mycelium. The strain was originally isolated from a soil sample collected from a road side in Nassau, Bahamas. Here we describe the features of this organism, together with the complete genome sequence and annotation. This is the first complete genome sequence of the actinobacterial suborder Glycomycineae. The 6,841,557 bp long single replicon genome with its 6487 protein-coding and 53 RNA genes is part of the Genomic Encyclopedia of Bacteria and Archaea project.

Munk, Christine [U.S. Department of Energy, Joint Genome Institute; Lapidus, Alla L. [U.S. Department of Energy, Joint Genome Institute; Copeland, A [U.S. Department of Energy, Joint Genome Institute; Jando, Marlen [DSMZ - German Collection of Microorganisms and Cell Cultures GmbH, Braunschweig, Germany; Mayilraj, Shanmugam [DSMZ - German Collection of Microorganisms and Cell Cultures GmbH, Braunschweig, Germany; Glavina Del Rio, Tijana [U.S. Department of Energy, Joint Genome Institute; Nolan, Matt [U.S. Department of Energy, Joint Genome Institute; Chen, Feng [U.S. Department of Energy, Joint Genome Institute; Han, Cliff [Los Alamos National Laboratory (LANL); Detter, J. Chris [U.S. Department of Energy, Joint Genome Institute; Bruce, David [Los Alamos National Laboratory (LANL); Goodwin, Lynne A. [Los Alamos National Laboratory (LANL); Chain, Patrick S. G. [Lawrence Livermore National Laboratory (LLNL); Pitluck, Sam [U.S. Department of Energy, Joint Genome Institute; Goker, Markus [DSMZ - German Collection of Microorganisms and Cell Cultures GmbH, Braunschweig, Germany; Ovchinnikova, Galina [U.S. Department of Energy, Joint Genome Institute; Pati, Amrita [U.S. Department of Energy, Joint Genome Institute; Ivanova, N [U.S. Department of Energy, Joint Genome Institute; Mavromatis, K [U.S. Department of Energy, Joint Genome Institute; Chen, Amy [U.S. Department of Energy, Joint Genome Institute; Palaniappan, Krishna [U.S. Department of Energy, Joint Genome Institute; Land, Miriam L [ORNL; Hauser, Loren John [ORNL; Chang, Yun-Juan [ORNL; Jeffries, Cynthia [Oak Ridge National Laboratory (ORNL); Bristow, James [U.S. Department of Energy, Joint Genome Institute; Eisen, Jonathan [U.S. Department of Energy, Joint Genome Institute; Markowitz, Victor [U.S. Department of Energy, Joint Genome Institute; Hugenholtz, Philip [U.S. Department of Energy, Joint Genome Institute; Kyrpides, Nikos C [U.S. Department of Energy, Joint Genome Institute; Klenk, Hans-Peter [DSMZ - German Collection of Microorganisms and Cell Cultures GmbH, Braunschweig, Germany

2009-01-01T23:59:59.000Z

319

Complete genome sequence of Dyadobacter fermentans type strain (NS114T)  

SciTech Connect (OSTI)

Dyadobacter fermentans (Chelius MK and Triplett EW, 2000) is the type species of the genus Dyadobacter. It is of phylogenetic interest because of its location in the Cytophagaceae, a very diverse family within the order 'Sphingobacteriales'. D. fermentans has a mainly respiratory metabolism, stains Gram-negative, is non-motile and oxidase and catalase positive. It is characterized by the production of cell filaments in ageing cultures, a flexirubin-like pigment and its ability to ferment glucose, which is almost unique in the aerobically living members of this taxonomically difficult family. Here we describe the features of this organism, together with the complete genome sequence, and annotation. This is the first complete genome sequence of the 'sphingobacterial' genus Dyadobacter, and this 6,967,790 bp long single replicon genome with its 5804 protein-coding and 50 RNA genes is part of the Genomic Encyclopedia of Bacteria and Archaea project.

Lang, Elke; Lapidus, Alla; Chertkov, Olga; Brettin, Thomas; Detter, John C.; Han, Cliff; Copeland, Alex; Glavina Del Rio, Tijana; Nolan, Matt; Chen, Feng; Lucas, Susan; Tice, Hope; Cheng, Jan-Fang; Land, Miriam; Hauser, Loren; Chang, Yun-Juan; Jeffries, Cynthia; Bruce, David; Goodwin, Lynne; Pitluck, Sam; Ovchinnikova, Galina; Pati, Amrita; Ivanova, Natalia; Mavromatis, Konstantinos; Chen, Amy; Chain, Patrick; Bristow, Jim; Eisen, Jonathan A.; Markowitz, Victor; Hugenholtz, Philip; Goker, Markus; Rohde, Manfred; Kyrpides, Nikos C; Klenk, Hans-Peter

2009-05-20T23:59:59.000Z

320

ATGC: a database of orthologous genes from closely related prokaryotic genomes and a research platform for microevolution of prokaryotes  

SciTech Connect (OSTI)

The database of Alignable Tight Genomic Clusters (ATGCs) consists of closely related genomes of archaea and bacteria, and is a resource for research into prokaryotic microevolution. Construction of a data set with appropriate characteristics is a major hurdle for this type of studies. With the current rate of genome sequencing, it is difficult to follow the progress of the field and to determine which of the available genome sets meet the requirements of a given research project, in particular, with respect to the minimum and maximum levels of similarity between the included genomes. Additionally, extraction of specific content, such as genomic alignments or families of orthologs, from a selected set of genomes is a complicated and time-consuming process. The database addresses these problems by providing an intuitive and efficient web interface to browse precomputed ATGCs, select appropriate ones and access ATGC-derived data such as multiple alignments of orthologous proteins, matrices of pairwise intergenomic distances based on genome-wide analysis of synonymous and nonsynonymous substitution rates and others. The ATGC database will be regularly updated following new releases of the NCBI RefSeq. The database is hosted by the Genomics Division at Lawrence Berkeley National laboratory and is publicly available at http://atgc.lbl.gov.

Novichkov, Pavel S.; Ratnere, Igor; Wolf, Yuri I.; Koonin, Eugene V.; Dubchak, Inna

2009-07-23T23:59:59.000Z

Note: This page contains sample records for the topic "human genome project" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


321

Project Management Practices  

Energy Savers [EERE]

on the DOE Project Management web page. 1.2 INTENDED USE Federal Project Directors, Contracting Officers, Contracting Officer's Technical Representatives, Integrated Project Team...

322

PROCEDURES FOR ARC PROJECTS  

E-Print Network [OSTI]

PROCEDURES FOR ARC PROJECTS Revised - May 2013 Agricultural Research Center Washington State University #12;Table of Contents THE PROJECT SYSTEM, AN INTRODUCTION................................................................................. 5 DEVELOPING AN ARC PROJECT

Collins, Gary S.

323

Enhancer Identification through Comparative Genomics  

SciTech Connect (OSTI)

With the availability of genomic sequence from numerousvertebrates, a paradigm shift has occurred in the identification ofdistant-acting gene regulatory elements. In contrast to traditionalgene-centric studies in which investigators randomly scanned genomicfragments that flank genes of interest in functional assays, the modernapproach begins electronically with publicly available comparativesequence datasets that provide investigators with prioritized lists ofputative functional sequences based on their evolutionary conservation.However, although a large number of tools and resources are nowavailable, application of comparative genomic approaches remains far fromtrivial. In particular, it requires users to dynamically consider thespecies and methods for comparison depending on the specific biologicalquestion under investigation. While there is currently no single generalrule to this end, it is clear that when applied appropriately,comparative genomic approaches exponentially increase our power ingenerating biological hypotheses for subsequent experimentaltesting.

Visel, Axel; Bristow, James; Pennacchio, Len A.

2006-10-01T23:59:59.000Z

324

Genome Engineering with TAL Effector Nucleases  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Genome Engineering with TAL Effector Nucleases Print Genome engineering (GE), an emerging discipline in which a DNA sequence is altered at a single position, has a wide variety of...

325

GWIDD: Genome-wide protein docking database  

E-Print Network [OSTI]

Structural information on interacting proteins is important for understanding life processes at the molecular level. Genome-wide docking database is an integrated resource for structural studies of protein–protein interactions on the genome scale...

Kundrotas, Petras J.; Zhu, Zhengwei; Vasker, Ilya A.

2009-11-09T23:59:59.000Z

326

Genome Size Varaiation in D. melanogaster  

E-Print Network [OSTI]

in genome size may account for some of the missing heritability. We measured female genome sizes for 34 Drosophila melanogaster inbred strains that derived from isofemale lines established from a natural population in Raleigh, NC, in addition to a group...

Alfrejd, Benjamin

2011-04-26T23:59:59.000Z

327

From genomics to chemical genomics: new developments in KEGG  

E-Print Network [OSTI]

The increasing amount of genomic and molecular information is the basis for understanding higherorder biological systems, such as the cell and the 15 organism, and their interactions with the environment, as well as for medical, industrial and other practical applications. The KEGG resource

Minoru Kanehisa; Susumu Goto; Masahiro Hattori; Kiyoko F. Aoki-kinoshita; Masumi Itoh; Shuichi Kawashima; Toshiaki Katayama; Michihiro Araki; Mika Hirakawa

2006-01-01T23:59:59.000Z

328

HUMAN RESOURCES SIMON FRASER UNIVERSITY  

E-Print Network [OSTI]

) by coordinating budget submissions, estimating and preparing cost projections, liaising with PurchasingHUMAN RESOURCES SIMON FRASER UNIVERSITY ADMINISTRATIVE & PROFESSIONAL JOB DESCRIPTION Position of the position in one or two sentences. Manages the Department's operating, capital, temporary instruction

329

The Genome of the Epsilonproteobacterial Chemolithoautotroph Sulfurimonas dentrificans  

E-Print Network [OSTI]

10 , Jörg Simon 11 , and the USF Genomics Class 2, ? Biologyof coverage at the Production Genomics Facility of the Joint

Sievert, Stefan M.; USF Genomics Class

2008-01-01T23:59:59.000Z

330

Genome Sequence of the Pea Aphid Acyrthosiphon The International Aphid Genomics Consortium"  

E-Print Network [OSTI]

Genome Sequence of the Pea Aphid Acyrthosiphon pisum The International Aphid Genomics Consortium we present the 464 Mb draft genome assembly of the pea aphid Acyrthosiphon pisum. This first published whole genome sequence of a basal hemimetabolous insect provides an outgroup to the multiple

Paris-Sud XI, Université de

331

Mechanisms of Low Dose Radio-Suppression of Genomic Instability  

SciTech Connect (OSTI)

The major goal of this project is to contribute toward the elucidation of the impact of long term low dose radiation on genomic stability. We have created and characterized novel technologies for delivering long term low dose radiation to animals, and we have studied genomic stability by applying cutting edge molecular analysis technologies. Remarkably, we have found that a dose rate that is 300X higher than background radiation does not lead to any detectable genomic damage, nor is there any significant change in gene expression for genes pertinent to the DNA damage response. These results point to the critical importance of dose rate, rather than just total dose, when evaluating public health risks and when creating regulatory guidelines. In addition to these studies, we have also further developed a mouse model for quantifying cells that have undergone a large scale DNA sequence rearrangement via homologous recombination, and we have applied these mice in studies of both low dose radiation and space radiation. In addition to more traditional approaches for assessing genomic stability, we have also explored radiation and possible beneficial effects (adaptive response), long term effects (persistent effects) and effects on communication among cells (bystander effects), both in vitro and in vivo. In terms of the adaptive response, we have not observed any significant induction of an adaptive response following long term low dose radiation in vivo, delivered at 300X background. In terms of persistent and bystander effects, we have revealed evidence of a bystander effect in vivo and with researchers at and demonstrated for the first time the molecular mechanism by which cells “remember” radiation exposure. Understanding the underlying molecular mechanisms by which radiation can induce genomic instability is fundamental to our ability to assess the biological impact of low dose radiation. Finally, in a parallel set of studies we have explored the effects of heavy iron particle radiation on large scale sequence rearrangements and we have discovered tissue specific differences in sensitivity to homologous recombination. DOE support has given rise to critical new knowledge about the biological impact of low dose rate radiation and about the underlying mechanisms that govern genomic stability in response to radiation exposure. This work has spurred interest in radiation among MIT scientists, and has fostered ongoing research projects that will continue to contribute toward our understanding of the biological effects of low dose radiation exposure.

Engelward, Bevin P

2009-09-16T23:59:59.000Z

332

Joint Genome Institute's Automation Approach and History  

E-Print Network [OSTI]

Joint Genome Institute’s Automation Approach and Historythroughput environment; – automation does not necessarilyissues “Islands of Automation” – modular instruments with

Roberts, Simon

2006-01-01T23:59:59.000Z

333

Project Management Lessons Learned  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

The guide supports DOE O 413.3A, Program and Project Management for the Acquisition of Capital Assets, and aids the federal project directors and integrated project teams in the execution of projects.

2008-08-05T23:59:59.000Z

334

Genome Stability of Lyme Disease Spirochetes: Comparative Genomics of Borrelia burgdorferi Plasmids  

SciTech Connect (OSTI)

Lyme disease is the most common tick-borne human illness in North America. In order to understand the molecular pathogenesis, natural diversity, population structure and epizootic spread of the North American Lyme agent, Borrelia burgdorferi sensu stricto, a much better understanding of the natural diversity of its genome will be required. Towards this end we present a comparative analysis of the nucleotide sequences of the numerous plasmids of B. burgdorferi isolates B31, N40, JD1 and 297. These strains were chosen because they include the three most commonly studied laboratory strains, and because they represent different major genetic lineages and so are informative regarding the genetic diversity and evolution of this organism. A unique feature of Borrelia genomes is that they carry a large number of linear and circular plasmids, and this work shows that strains N40, JD1, 297 and B31 carry related but non-identical sets of 16, 20, 19 and 21 plasmids, respectively, that comprise 33-40% of their genomes. We deduce that there are at least 28 plasmid compatibility types among the four strains. The B. burgdorferi {approx}900 Kbp linear chromosomes are evolutionarily exceptionally stable, except for a short {le}20 Kbp plasmid-like section at the right end. A few of the plasmids, including the linear lp54 and circular cp26, are also very stable. We show here that the other plasmids, especially the linear ones, are considerably more variable. Nearly all of the linear plasmids have undergone one or more substantial inter-plasmid rearrangements since their last common ancestor. In spite of these rearrangements and differences in plasmid contents, the overall gene complement of the different isolates has remained relatively constant.

Casjens S. R.; Dunn J.; Mongodin, E. F.; Qiu, W.-G.; Luft, B. J.; Schutzer, S. E.; Gilcrease, E. B.; Huang, W. M.; Vujadinovic, M.; Aron, J. K.; Vargas, L. C.; Freeman, S.; Radune, D.; Weidman, J. F.; Dimitrov, G. I.; Khouri, H. M.; Sosa, J. E.; Halpin, R. A.; Fraser, C. M.

2012-03-14T23:59:59.000Z

335

UNL Core for Applied Genomics and Ecology  

E-Print Network [OSTI]

UNL Core for Applied Genomics and Ecology Bioinformatics training Roche 454 GS-FLX Registration, Microbiomes, Variant Analysis, Whole Genomes, Transcriptomes Data Analysis and Statistics CAGE database and employer. University of Nebraska-Lincoln*Core for Applied Genomics and Ecology* 323 Filley Hall *Lincoln

Farritor, Shane

336

Bridging mycorrhizal genomics, metagenomics and forest ecology  

E-Print Network [OSTI]

Meetings Bridging mycorrhizal genomics, metagenomics and forest ecology 6th New Phytologist of easily cultured saprotrophic fungi (among the first three published genomes were the models Saccharomyces or biotechnological interest, genomics is now poised to rapidly permeate the fields of fungal ecology and evolution

Pringle, Anne

337

Leading Edge Bacterial Genomics and Pathogen Evolution  

E-Print Network [OSTI]

Leading Edge Review Bacterial Genomics and Pathogen Evolution David M. Raskin,1 Rekha Seshadri,2 Medical School, Boston, MA 02115, USA 2 The Institute for Genomic Research, 9712 Medical Center Drive.02.002 The availability of hundreds of bacterial genome sequences has altered the study of bacte- rial pathogenesis

Mekalanos, John

338

One day seminar: Genetics and Genomics of  

E-Print Network [OSTI]

SCHOOL OF MEDICINE One day seminar: Genetics and Genomics of Infectious Diseases Malaria and TB 14th June 2013 University of St Andrews - School of Medicine Pathogen genome research allows exquisite to understanding disease progression. Pathogen genome sequencing is accessible to most. Outputs have broad

Brierley, Andrew

339

INVITED: Comparative Microbial Genomics Giri Narasimhan  

E-Print Network [OSTI]

INVITED: Comparative Microbial Genomics Giri Narasimhan Bioinformatics Research Group (Bio, comparative genomics holds the keys to decipher and mine this wealth of information. We discuss the diverse ways in which the availability of comparative genomics data allows us to answer more questions

Narasimhan, Giri

340

Bioinformatics The Maize Genetics and Genomics Database.  

E-Print Network [OSTI]

Bioinformatics The Maize Genetics and Genomics Database. The Community Resource for Access 50011­3260 (T.E.S.) The Maize Genetics and Genomics Database (MaizeGDB) serves the maize (Zea mays data types available through MaizeGDB. MISSION AND SCOPE The Maize Genetics and Genomics Database

Brendel, Volker

Note: This page contains sample records for the topic "human genome project" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


341

Windy Gap Firming Project  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Infrastructure projects Interconnection OASIS OATT Windy Gap Firming Project, Final Environmental Impact Statement, DOEEIS-0370 (cooperating agency) Western's proposed...

342

Perspectives on Project Finance  

Broader source: Energy.gov [DOE]

Plenary III: Project Finance and Investment Perspectives on Project Finance John May, Managing Partner, Stern Brothers & Co.

343

NSTX Upgrade Project Project Execution Plan  

E-Print Network [OSTI]

NSTX Upgrade Project Project Execution Plan 6 PPPL Laboratory Director S.Prager Deputy Director.Gentile Centerstack Dsgn & Fab J. Chrzanowski NSTX Upgrade Project Manager R. Strykowsky Deputy and Construction Manager E. Perry Project Controls S. Langish NSTXCenterstack Manager L. Dudek NSTXNeutral Beam Manager T

Princeton Plasma Physics Laboratory

344

NSTX Upgrade Project Project Execution Plan  

E-Print Network [OSTI]

NSTX Upgrade Project Project Execution Plan Appendix 1 - WBS Dictionary 25 Appendix 1 - NSTX Upgrade Project Work Breakdown Structure This Work Breakdown Structure (WBS) organizes and defines the scope of the NSTX Upgrade using the WBS as established by the original NSTX project and modified

Princeton Plasma Physics Laboratory

345

CIMI PROJECT LONG TERM THEMATIC PROJECT  

E-Print Network [OSTI]

thematic projects (3 months) on specific topics in mathematics, computer science and their interactionsCIMI PROJECT LONG TERM THEMATIC PROJECT This document aims at providing guidance on the format to be used when submitting a scientific project to CIMI Executive Committee. CIMI will support long term

Ledoux, Michel

346

Livingston Solar Canopy Project The Project  

E-Print Network [OSTI]

,000 high efficiency solar panels on canopy structures over two major surface parking areasLivingston Solar Canopy Project The Project: This project entails the installation of more than 40. In conjunction with the existing 1.4 megawatt solar energy facility on this campus, this project will generate

Delgado, Mauricio

347

Information Visualization Graduate Project (Group Project)  

E-Print Network [OSTI]

Information Visualization Fall 2011 Graduate Project (Group Project) (100 points total) Handed out:59PM Research Article due by online submission on Sunday, December 11, 2011, 11:59PM Project Demo due last week of classes The idea of the project is to take the knowledge and background that you

Rusu, Adrian

348

Project Title Project Sponsor (funding agency)  

E-Print Network [OSTI]

and procedures applicable to the above project; and we confirm that the PI is eligible to apply in accordance Project Title Project Sponsor (funding agency) Declaration of Principal Investigator (PI) I certify that: I agree that my participation in the project must be in accordance with all

Saskatchewan, University of

349

Chopwell Wood Health Project  

E-Print Network [OSTI]

Chopwell Wood Health Project An innovative project of school visits and General Practitioner. The project took place at Chopwell Wood a 360 hectare mixed woodland managed by the Forestry Commission to carry on being involved in the project. Next stage of the project Although the project leader has now

350

CROP & SOIL SCIENCES Quantitative Genomics  

E-Print Network [OSTI]

CROP & SOIL SCIENCES Quantitative Genomics Committee Membership Dr. Scott Jackson - committee chair Dr. Peng-Wah Chee Department of Crop & Soil Sciences Department of Crop & Soil Sciences University of Horticulture Department of Crop & Soil Sciences University of Georgia University of Georgia 2360 Rainwater Rd

Arnold, Jonathan

351

Microfluidic Devices for Genomic Analysis  

E-Print Network [OSTI]

the puzzle of interactions between proteins is far more complicated than deciphering genomes, due to the lack, and industry. Fractionation of biological molecules, such as nucleic acids and proteins, plays a central role of proteins' equivalent of amplification, fractionation and sequencing techniques. Micro- and nano

352

Nuclear Organization and Genome Function  

E-Print Network [OSTI]

Nuclear Organization and Genome Function Kevin Van Bortle and Victor G. Corces Department-range interactions and have proposed roles in nuclear organization. In this review, we explore recent findings for the roles of insulators in nuclear organization. 163 Annu.Rev.CellDev.Biol.2012.28:163-187.Downloadedfromwww

Corces, Victor G.

353

Sustainability Project Fund Application Form Requirements Project Title  

E-Print Network [OSTI]

Sustainability Project Fund Application Form Requirements Project Title: Budget Requested: Applicant/Project Leader: Faculty/Department: Email: Daytime Phone: Project Team: (Please include. Project Overview Project summary: · Provide a brief background, describing the project, objectives

Volesky, Bohumil

354

Human Factors design and evaluation criteria applied to academic and instructional websites.  

E-Print Network [OSTI]

??This culminating project applies Human Factors principles to the analysis of various web designs. This culminating project consists of three major parts. The first chapter… (more)

Mendez, Veronica

2015-01-01T23:59:59.000Z

355

Construction of an integrated database to support genomic sequence analysis  

SciTech Connect (OSTI)

The central goal of this project is to develop an integrated database to support comparative analysis of genomes including DNA sequence data, protein sequence data, gene expression data and metabolism data. In developing the logic-based system GenoBase, a broader integration of available data was achieved due to assistance from collaborators. Current goals are to easily include new forms of data as they become available and to easily navigate through the ensemble of objects described within the database. This report comments on progress made in these areas.

Gilbert, W.; Overbeek, R.

1994-11-01T23:59:59.000Z

356

The ecoresponsive genome of Daphnia pulex  

SciTech Connect (OSTI)

This document provides supporting material related to the sequencing of the ecoresponsive genome of Daphnia pulex. This material includes information on materials and methods and supporting text, as well as supplemental figures, tables, and references. The coverage of materials and methods addresses genome sequence, assembly, and mapping to chromosomes, gene inventory, attributes of a compact genome, the origin and preservation of Daphnia pulex genes, implications of Daphnia's genome structure, evolutionary diversification of duplicated genes, functional significance of expanded gene families, and ecoresponsive genes. Supporting text covers chromosome studies, gene homology among Daphnia genomes, micro-RNA and transposable elements and the 46 Daphnia pulex opsins. 36 figures, 50 tables, 183 references.

Colbourne, John K.; Pfrender, Michael E.; Gilbert, Donald; Thomas, W. Kelley; Tucker, Abraham; Oakley, Todd H.; Tokishita, Shinichi; Aerts, Andrea; Arnold, Georg J.; Basu, Malay Kumar; Bauer, Darren J.; Caceres, Carla E.; Carmel, Liran; Casola, Claudio; Choi, Jeong-Hyeon; Detter, John C.; Dong, Qunfeng; Dusheyko, Serge; Eads, Brian D.; Frohlich, Thomas; Geiler-Samerotte, Kerry A.; Gerlach, Daniel; Hatcher, Phil; Jogdeo, Sanjuro; Krijgsveld, Jeroen; Kriventseva, Evgenia V; Kültz, Dietmar; Laforsch, Christian; Lindquist, Erika; Lopez, Jacqueline; Manak, Robert; Muller, Jean; Pangilinan, Jasmyn; Patwardhan, Rupali P.; Pitluck, Samuel; Pritham, Ellen J.; Rechtsteiner, Andreas; Rho, Mina; Rogozin, Igor B.; Sakarya, Onur; Salamov, Asaf; Schaack, Sarah; Shapiro, Harris; Shiga, Yasuhiro; Skalitzky, Courtney; Smith, Zachary; Souvorov, Alexander; Sung, Way; Tang, Zuojian; Tsuchiya, Dai; Tu, Hank; Vos, Harmjan; Wang, Mei; Wolf, Yuri I.; Yamagata, Hideo; Yamada, Takuji; Ye, Yuzhen; Shaw, Joseph R.; Andrews, Justen; Crease, Teresa J.; Tang, Haixu; Lucas, Susan M.; Robertson, Hugh M.; Bork, Peer; Koonin, Eugene V.; Zdobnov, Evgeny M.; Grigoriev, Igor V.; Lynch, Michael; Boore, Jeffrey L.

2011-02-04T23:59:59.000Z

357

Spring Creek Project for Ideas, Nature, and the Written Word Call for Nominations: Graduate Student Research and Writing Retreat  

E-Print Network [OSTI]

Spring Creek Project for Ideas, Nature, and the Written Word Call for Nominations: Graduate Student on a collaborative project or two graduate students who each have individual projects are invited to nominate graduate students in the humanities or environmental sciences

Grünwald, Niklaus J.

358

From Human Genome to Materials "Genome" | U.S. DOE Office of Science  

Office of Science (SC) Website

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear SecurityTensile Strain Switched5 Industrial CarbonArticles News(SC) CCIScatteringFacilitiesU.S.Frequently

359

Stories of Discovery & Innovation: From Human Genome to Materials "Genome"  

Office of Science (SC) Website

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear SecurityTensile Strain Switched5 IndustrialIsadoreConnecticutPhotos of AECSign Up for E-mail UpdatesSouthSpiro| U.S.

360

Update on human genome completion and annotations: Protein information  

E-Print Network [OSTI]

and Daniel W. Nebert2 * 1 Director of PIR, Department of Biochemistry & Molecular Biology, Georgetown revised form): 11th January 2004 Abstract The Protein Information Resource (PIR) recently joinedProt--the Universal Protein Resource--which now unifies the PIR, Swiss-Prot and TrEMBL databases. The PIRSF (Super

Note: This page contains sample records for the topic "human genome project" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


361

Accelerated Evolution of Conserved Noncoding Sequences in the Human Genome  

E-Print Network [OSTI]

associated with CNSs accelerated in chimpanzee. (F)associated with CNSs accelerated in mouse. (G) CNScomponent associations of accelerated CNSs (adjustment for

Prambhakar, Shyam; Noonan, James P.; Paabo, Svante; Rubin, Edward M.

2006-01-01T23:59:59.000Z

362

Human Genome News: Workshop on sequencing by hybridization  

SciTech Connect (OSTI)

A brief description of the Second International Workshop on Sequencing by Hybridization as held in Woodlands, Texas October 28--30, 1993 is provided in this report. Highlights of sessions entitled Chemistry and Analogs, Engineering and Automation, Hybridization Data and Theory and Informatics are given.

Not Available

1994-01-01T23:59:59.000Z

363

Project Sponsor Professor Peter  

E-Print Network [OSTI]

Project Sponsor Professor Peter McGearoge Project Director Nicki Matthew Audit / Quality Mazars Architect IT ServicesProcess Owners Build Team Lead Nicki Matthew Project Manager ­ Unit4 Joe Cairney Student Lifecycle Project Board InfrastructureDBA's TBC TBC TBC Process 1 Process 2 Project Sponsor ­ Unit

Levi, Ran

364

Project Structure Elke Karrenberg  

E-Print Network [OSTI]

Project Structure Elke Karrenberg Project Manager, Head of Personnel Development Phone +49 6131 39-20634 Dr. Jana Leipold Project Staff, Personnel Development Consultant Phone +49 6131 39-25433 Antje Swietlik Project Staff Phone +49 6131 39-20140 Project Office JGU Leadership Forum Universitatis 3, Room 00

Kaus, Boris

365

Complete genome sequence of the melanogenic marine bacterium Marinomonas mediterranea type strain (MMB-1T)  

SciTech Connect (OSTI)

Marinomonas mediterranea MMB-1 T Solano & Sanchez-Amat 1999 belongs to the family Oceanospirillaceae within the phylum Proteobacteria. This species is of interest because it is the only species described in the genus Marinomonas to date that can synthesize melanin pigments, which is mediated by the activity of a tyrosinase. M. mediterranea expresses other oxidases of biotechnological interest, such as a multicopper oxidase with laccase activity and a novel L-lysine-epsilon-oxidase. The 4,684,316 bp long genome harbors 4,228 proteincoding genes and 98 RNA genes and is a part of the Genomic Encyclopedia of Bacteria and Archaea project.

Lucas-Elio, Patricia [University of Murcia, Murcia, Spain; Goodwin, Lynne A. [Los Alamos National Laboratory (LANL); Woyke, Tanja [U.S. Department of Energy, Joint Genome Institute; Pitluck, Sam [U.S. Department of Energy, Joint Genome Institute; Nolan, Matt [U.S. Department of Energy, Joint Genome Institute; Kyrpides, Nikos C [U.S. Department of Energy, Joint Genome Institute; Detter, J C [U.S. Department of Energy, Joint Genome Institute; Copeland, A [U.S. Department of Energy, Joint Genome Institute; Teshima, Hazuki [Los Alamos National Laboratory (LANL); Bruce, David [Los Alamos National Laboratory (LANL); Detter, J. Chris [U.S. Department of Energy, Joint Genome Institute; Tapia, Roxanne [Los Alamos National Laboratory (LANL); Han, Cliff [Los Alamos National Laboratory (LANL); Land, Miriam L [ORNL; Ivanova, N [U.S. Department of Energy, Joint Genome Institute; Mikhailova, Natalia [U.S. Department of Energy, Joint Genome Institute; Johnston, Andrew W. B. [University of East Anglia, Norwich, United Kingdom; Sanchez-Amat, Antonio [University of Murcia, Murcia, Spain

2012-01-01T23:59:59.000Z

366

E-Print Network 3.0 - artificial genome model Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Genomes: Choices to Make The first sequenced genome of a plant, Summary: in plant genomics re- search. Many of the obvious candidates for genome sequencing, model species......

367

E-Print Network 3.0 - applying whole-genome studies Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

(Lec 19) Picture Copyright: AccessExcellence @ the National Museum of Health Summary: Genomics Comparison of whole genomes. - Whole genome sequencing - Whole genome annotation &...

368

E-Print Network 3.0 - adaptive responses genomic Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Selected Topics in Molecular Biology Summary: genome variation - cancer genomes Genomics of the adaptive immune system Ancient genomes Synthetic... MOLECULAR BIOLOGY...

369

Part II: Project Summaries Project Summaries  

E-Print Network [OSTI]

Part II: Project Summaries Part II Project Summaries #12;22 Math & Computational Sciences Division generally cannot be achieved for reasonable computational cost. Applications that require modeling of this project is to advance the state of the art in electromagnetic computations by eliminating three existing

Perkins, Richard A.

370

CS348 Project 1 Oracle Project  

E-Print Network [OSTI]

CS348 Project 1 Oracle Project Due Date: 2/12/2009 You are going to use Oracle to design a simple; if nothing else, mark each query with its number. Turnin You may turn in the project for grading using the procedure described below. Run the following shell command (see 'man turnin' for details): turnin -c cs348

Elmagarmid, Ahmed K.

371

Project Name Project Number Tagging Type  

E-Print Network [OSTI]

Project Name Project Number Primary Tagging Type Secondary Tagging Type Fish Species Tagging/ Secondary Legal Driver (BiOp, MOA, Accord, etc.) Tagging Purpose Funded Entity Tagging Location Retrieval CWT Recovery Project 2010-036-00 CWT PIT Chinook, coho retrieval, analysis, address PSMFC sampling

372

project.m  

E-Print Network [OSTI]

function project(u,w) %last updated 5/9/94 %PROJECT Projecting vector U onto vector W orthogonally. Vectors % U and W can be either a pair of 2D or 3D ...

373

Super Projects (Arkansas)  

Broader source: Energy.gov [DOE]

A 2004 amendment to the state constitution authorizes the state to attract super projects by issuing bonds to fund a project’s infrastructure, limited to 5% of the net general revenues during the...

374

Project Selection - Record Keeping  

E-Print Network [OSTI]

4-H members have many project areas to choose from, depending on where they live. Members should consult with their parents and 4-H leaders when choosing a project. This publication outlines project considerations....

Howard, Jeff W.

2005-05-10T23:59:59.000Z

375

Cassava Genomics: can genomic technology benefit smallholder farmers in Africa? (2014 DOE JGI Genomics of Energy & Environment Meeting)  

SciTech Connect (OSTI)

Steve Rounsley of the University of Arizona speaks at the 9th Annual Genomics of Energy & Environment Meeting on March 20, 2014 in Walnut Creek, Calif.

Rounsley, Steve [University of Arizona

2014-03-20T23:59:59.000Z

376

Enabling sample tracking in and reducing variability in DNA library construction  

E-Print Network [OSTI]

The Broad Institute is a world leader in genomic sequencing. The Institute gained prominence during the Human Genome Project and has continued to be the nation's leading public laboratory for genomic sequencing projects. ...

Penake, David A. (David Allen)

2006-01-01T23:59:59.000Z

377

Hanford Environmental Dose Reconstruction Project. Monthly report  

SciTech Connect (OSTI)

The objective of the Hanford Environmental Dose Reconstruction (HEDR) Project is to estimate the radiation doses that individuals and populations could have received from nuclear operations at Hanford since 1944. The independent Technical Steering Panel (TSP) provides technical direction. The project is divided into the following technical tasks. These tasks correspond to the path radionuclides followed from release to impact on humans (dose estimates):Source Terms, Environmental Transport, Environmental Monitoring Data, Demography, Food Consumption, and Agriculture, and Environmental Pathways and Dose Estimates.

Cannon, S.D.; Finch, S.M. [comps.

1992-10-01T23:59:59.000Z

378

Keynote Presentation: Genome Beat (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)  

SciTech Connect (OSTI)

Carl Zimmer, a reporter for the New York Times, speaks on "The Genome Beat," the opening keynote presentation at the JGI User 7th Annual Genomics of Energy & Environment Meeting on March 22, 2012 in Walnut Creek, Calif

Zimmer, Carl [New York Times] [New York Times

2012-03-20T23:59:59.000Z

379

Keynote Presentation: Genome Beat (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)  

ScienceCinema (OSTI)

Carl Zimmer, a reporter for the New York Times, speaks on "The Genome Beat," the opening keynote presentation at the JGI User 7th Annual Genomics of Energy & Environment Meeting on March 22, 2012 in Walnut Creek, Calif

Zimmer, Carl [New York Times

2013-01-22T23:59:59.000Z

380

Genome Announcement1 Draft genome sequence of the electricity producing3  

E-Print Network [OSTI]

1 Genome Announcement1 2 Draft genome sequence of the electricity producing3 Thermincola potens of insoluble electron acceptors by model Gram-negative64 bacteria such as Geobacter or Shewanella species (4

Hazen, Terry

Note: This page contains sample records for the topic "human genome project" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


381

Falls Creek Hydroelectric Project  

SciTech Connect (OSTI)

This project was for planning and construction of a 700kW hydropower project on the Fall River near Gustavus, Alaska.

Gustavus Electric Company; Richard Levitt; DOE Project Officer - Keith Bennett

2007-06-12T23:59:59.000Z

382

EV Project Overview Report  

Broader source: Energy.gov (indexed) [DOE]

Leafs Enrolled to Date EV Project Chevrolet Volts Enrolled to Date EV Project Smart Electric Drives Enrolled to Date Distance Driven (mi) Phoenix, AZ Metropolitan Area 274...

383

EV Project Overview Report  

Broader source: Energy.gov (indexed) [DOE]

Leafs Enrolled to Date EV Project Chevrolet Volts Enrolled to Date EV Project Smart Electric Drives Enrolled to Date Distance Driven (mi) Phoenix, AZ Metropolitan Area 259...

384

Project Risk Management:.  

E-Print Network [OSTI]

?? The recent increase in international projects has resulted in higher risk along with difficulties in control and coordination. Effective project management can therefore be… (more)

Koelmeyer, Chris

2013-01-01T23:59:59.000Z

385

Contract/Project Management  

Broader source: Energy.gov (indexed) [DOE]

3 rd Quarter Overall Contract and Project Management Performance Metrics and Targets ContractProject Management Performance Metrics FY 2009 Target FY 2009 Actual Comment 1....

386

Project BETA Cover Page  

E-Print Network [OSTI]

and Distribution of the Project BETA articles were funded inproduct is discussed in the BETA articles. Western JournalProject BETA: Best practices in Evaluation and Treatment of

Cover Page, Project BETA

2012-01-01T23:59:59.000Z

387

EV Project Overview Report  

Broader source: Energy.gov (indexed) [DOE]

Report Project to date through March 2013 Charging Infrastructure Region Number of EV Project Charging Units Installed To Date Number of Charging Events Performed Electricity...

388

Project Finance and Investments  

Broader source: Energy.gov [DOE]

Plenary III: Project Finance and Investment Project Finance and Investments Chris Cassidy, National Business Renewable Energy Advisor, U.S. Department of Agriculture

389

Clean Coal Projects (Virginia)  

Broader source: Energy.gov [DOE]

This legislation directs the Virginia Air Pollution Control Board to facilitate the construction and implementation of clean coal projects by expediting the permitting process for such projects.

390

What are the (long-term) goals of these projects? Why is now the right time to  

E-Print Network [OSTI]

of the anatomical, molecular and circuit bases for the logical operations carried out by the human brain. The Human Brain Project (see Human Brain Project), based in Europe and led by H.M., aims to understand the human brain by simulating its functions through the use of supercomputers. The Brain Activity Map, with which

Columbia University

391

Comparative Mapping of the Alpaca Genome  

E-Print Network [OSTI]

Research Institute (NHGRI) at the National Institutes of Health (NIH) for low coverage (2X) whole genome sequencing, together with 21 other mammalian species. This was done primarily to use comparative genomic information to improve the annotation...; https://bacpac.chori.org/library.php?id=448) (Figure 5). Figure 5. Nyala's Accoyo Empress Carlotta. The first round of genome sequencing (VicPac1.0; http://www.ncbi.nlm. nih.gov/genome/905) was generated at the Broad Institute by whole...

Fagundes De Avila, Felipe

2014-08-06T23:59:59.000Z

392

Diatom Genomics (2009 JGI User Meeting)  

ScienceCinema (OSTI)

Ginger Armbrust from the University of Washington spoke about diatom genomics on March 26, 2009 at the DOE JGI User Meeting

Ambrust, Ginger

2011-04-25T23:59:59.000Z

393

Generalized genetical genomics : advanced methods and applications.  

E-Print Network [OSTI]

??Generalized genetical genomics (GGG) is a systems genetics approach that combines the analysis of genetic variation with population-wide assessment of variation in molecular traits in… (more)

Li, Yang

2010-01-01T23:59:59.000Z

394

GENOMIC RESOURCES NOTE Genomic Resources Notes accepted 1 February 201331 March  

E-Print Network [OSTI]

GENOMIC RESOURCES NOTE Genomic Resources Notes accepted 1 February 2013­31 March 2013 GENOMIC RESOURCES DEVELOPMENT CONSORTIUM,1 MATTHEW G. KING,2 SE´ BASTIEN RENAUT,3 LOREN H. RIESEBERG2,4 and HEATHER C. ROWE3 1 Molecular Ecology Resources Editorial Office, 6270 University Blvd, Vancouver, BC V6T 1Z4

Rieseberg, Loren

395

Hanford Environmental Dose Reconstruction Project Monthly Report  

SciTech Connect (OSTI)

The objective of the Hanford Environmental Dose Reconstruction Project is to estimate the radiation doses that populations could have received from nuclear operations at Hanford since 1944. The project is being managed and conducted by the Pacific Northwest Laboratory (PNL) under the direction of an independent Technical Steering Panel (TSP). The project is divided into the following technical tasks. These tasks correspond to the path radionuclides followed, from release to impact on humans (dose estimates): source terms; environmental transport; environmental monitoring data; demographics; agriculture; food habits; and environmental pathways and dose estimates. 3 figs.

Finch, S.M. (comp.)

1990-01-01T23:59:59.000Z

396

Genomic Sciences | Clean Energy | ORNL  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation ProposedUsingFun with Big Sky Learning Fun withGenepoolCrystals.Genome

397

Incorporating Genomics and Bioinformatics across the Life Sciences Curriculum  

SciTech Connect (OSTI)

Undergraduate life sciences education needs an overhaul, as clearly described in the National Research Council of the National Academies publication BIO 2010: Transforming Undergraduate Education for Future Research Biologists. Among BIO 2010's top recommendations is the need to involve students in working with real data and tools that reflect the nature of life sciences research in the 21st century. Education research studies support the importance of utilizing primary literature, designing and implementing experiments, and analyzing results in the context of a bona fide scientific question in cultivating the analytical skills necessary to become a scientist. Incorporating these basic scientific methodologies in undergraduate education leads to increased undergraduate and post-graduate retention in the sciences. Toward this end, many undergraduate teaching organizations offer training and suggestions for faculty to update and improve their teaching approaches to help students learn as scientists, through design and discovery (e.g., Council of Undergraduate Research [www.cur.org] and Project Kaleidoscope [www.pkal.org]). With the advent of genome sequencing and bioinformatics, many scientists now formulate biological questions and interpret research results in the context of genomic information. Just as the use of bioinformatic tools and databases changed the way scientists investigate problems, it must change how scientists teach to create new opportunities for students to gain experiences reflecting the influence of genomics, proteomics, and bioinformatics on modern life sciences research. Educators have responded by incorporating bioinformatics into diverse life science curricula. While these published exercises in, and guidelines for, bioinformatics curricula are helpful and inspirational, faculty new to the area of bioinformatics inevitably need training in the theoretical underpinnings of the algorithms. Moreover, effectively integrating bioinformatics into courses or independent research projects requires infrastructure for organizing and assessing student work. Here, we present a new platform for faculty to keep current with the rapidly changing field of bioinformatics, the Integrated Microbial Genomes Annotation Collaboration Toolkit (IMG-ACT). It was developed by instructors from both research-intensive and predominately undergraduate institutions in collaboration with the Department of Energy-Joint Genome Institute (DOE-JGI) as a means to innovate and update undergraduate education and faculty development. The IMG-ACT program provides a cadre of tools, including access to a clearinghouse of genome sequences, bioinformatics databases, data storage, instructor course management, and student notebooks for organizing the results of their bioinformatic investigations. In the process, IMG-ACT makes it feasible to provide undergraduate research opportunities to a greater number and diversity of students, in contrast to the traditional mentor-to-student apprenticeship model for undergraduate research, which can be too expensive and time-consuming to provide for every undergraduate. The IMG-ACT serves as the hub for the network of faculty and students that use the system for microbial genome analysis. Open access of the IMG-ACT infrastructure to participating schools ensures that all types of higher education institutions can utilize it. With the infrastructure in place, faculty can focus their efforts on the pedagogy of bioinformatics, involvement of students in research, and use of this tool for their own research agenda. What the original faculty members of the IMG-ACT development team present here is an overview of how the IMG-ACT program has affected our development in terms of teaching and research with the hopes that it will inspire more faculty to get involved.

Ditty, Jayna L.; Kvaal, Christopher A.; Goodner, Brad; Freyermuth, Sharyn K.; Bailey, Cheryl; Britton, Robert A.; Gordon, Stuart G.; Heinhorst, Sabine; Reed, Kelynne; Xu, Zhaohui; Sanders-Lorenz, Erin R.; Axen, Seth; Kim, Edwin; Johns, Mitrick; Scott, Kathleen; Kerfeld, Cheryl A.

2011-08-01T23:59:59.000Z

398

METLIN: MS/MS metabolite data from the MAGGIE Project  

DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

METLIN is a metabolite database for metabolomics containing over 50,000 structures, it also represents a data management system designed to assist in a broad array of metabolite research and metabolite identification by providing public access to its repository of current and comprehensive MS/MS metabolite data. An annotated list of known metabolites and their mass, chemical formula, and structure are available on the METLIN website. Each metabolite is conveniently linked to outside resources such as the the Kyoto Encyclopedia of Genes and Genomes (KEGG) for further reference and inquiry. MS/MS data is also available on many of the metabolites. The list is expanding continuously as more metabolite information is being deposited and discovered. [from http://metlin.scripps.edu/] Metlin is a component of the MAGGIE Project. MAGGIE is funded by the DOE Genomics: GTL and is an acronym for "Molecular Assemblies, Genes, and Genomics Integrated Efficiently."

399

A Middle Holocene Radiocarbon Date and the Geologic Context of Human Occupation in the Tulare Lake Basin of California  

E-Print Network [OSTI]

Flood Storage Project, Kings County, California, by Jill K.Storage Project, Kings County, California. Report on file atof Tulare Lake in Kings County, California, a human proximal

Gardner, Jill K.; Negrini, Robert M.; Sutton, Mark Q.; Wigand, Peter E.; Yohe, Robert M.

2005-01-01T23:59:59.000Z

400

ORIGINAL ARTICLE Comparative genomics of two newly isolated  

E-Print Network [OSTI]

ORIGINAL ARTICLE Comparative genomics of two newly isolated Dehalococcoides strains of Microbiology, Cornell University, Ithaca, NY, USA Comparative genomics of Dehalococcoides strains and an enrichment were performed using a microarray targeting genes from all available sequenced genomes

Alvarez-Cohen, Lisa

Note: This page contains sample records for the topic "human genome project" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


401

UV Decontamination of MDA Reagents for Single Cell Genomics  

E-Print Network [OSTI]

Reagents for Single Cell Genomics Janey Lee 1* , Damon TigheReagents for Single Cell Genomics Janey Lee 1 , Damon TigheAbstract Single cell genomics, the amplification and

Lee, Janey

2011-01-01T23:59:59.000Z

402

Structural Genomics of Minimal Organisms: Pipeline and Results  

E-Print Network [OSTI]

of recombinant proteins. J. Struct. Funct. Genomics 5:69-74.proteins. J. Struct. Funct. Genomics 5:69-74. Oganesyan,Structural Genomics of Minimal Organisms: Pipeline and

Kim, Sung-Hou

2008-01-01T23:59:59.000Z

403

Comparative genomics reveals evidence of marine adaptation in Salinispora species.  

E-Print Network [OSTI]

Orcutt B, et al: Ecological genomics of marine roseobacters.1037-1042. Penn and Jensen BMC Genomics 2012, 13:86 http://and Jensen: Comparative genomics reveals evidence of marine

Penn, Kevin; Jensen, Paul R

2012-01-01T23:59:59.000Z

404

Evolutionary Genomics of Life in (and from) the Sea  

E-Print Network [OSTI]

291: 1304-1351. Table 1. Genomics information on the webLBNL-59356 Evolutionary Genomics of Life in (and from) thean engine for comparative genomics. The six largest centers

Boore, Jeffrey L.

2009-01-01T23:59:59.000Z

405

Phytozome: A Comparative Platform for Green Plant Genomics  

E-Print Network [OSTI]

a growing plant comparative genomics resource. Nucleic AcidsL.A. (2011) The Sol Genomics Network (solgenomics.net):for comparative plant genomics. Nucleic Acids Res, 36, D959-

Goodstein, David M.

2012-01-01T23:59:59.000Z

406

Genome sequence of the Brown Norway rat yields insights into  

E-Print Network [OSTI]

Genome sequence of the Brown Norway rat yields insights into mammalian evolution Rat Genome Norway (BN) rat strain. The sequence represents a high-quality `draft' covering over 90% of the genome

Pachter, Lior

407

Target Selection and Deselection at the Berkeley Structural Genomics Center  

E-Print Network [OSTI]

gene-set concept. Annu Rev Genomics Hum Genet 2000;1:99-116.SE. A tour of structural genomics. Nat Rev Genet 2001;2(10):M, Wang LK. Structural genomics: a pipeline for providing

Chandonia, John-Marc; Kim, Sung-Hou; Brenner, Steven E.

2005-01-01T23:59:59.000Z

408

The Impact of Structural Genomics: Expectations and Outcomes  

E-Print Network [OSTI]

Choi et al. , J Struct Funct Genomics 4, 31-4 (2003). H. M.Center for Structural Genomics, sequence families of unknownMCSG) Northeast Structural Genomics Consortium, Novel folds

Chandonia, John-Marc; Brenner, Steven E.

2005-01-01T23:59:59.000Z

409

Ultracomputer Research Project  

SciTech Connect (OSTI)

This document presents significant accomplishments made on the Ultracomputer Research Project during CY92.

Gottlieb, A.

1992-10-01T23:59:59.000Z

410

[New hosts and vectors for genome cloning]. Progress report, 1990--1991  

SciTech Connect (OSTI)

The main goal of our project remains the development of new bacterial hosts and vectors for the stable propagation of human DNA clones in E. coli. During the past six months of our current budget period, we have (1) continued to develop new hosts that permit the stable maintenance of unstable features of human DNA, and (2) developed a series of vectors for (a) cloning large DNA inserts, (b) assessing the frequency of human sequences that are lethal to the growth of E. coli, and (c) assessing the stability of human sequences cloned in M13 for large-scale sequencing projects.

Not Available

1991-12-31T23:59:59.000Z

411

Illumina GA IIx& HiSeq 2000 Production Sequenccing and QC Analysis Pipelines at the DOE Joint Genome Institute  

SciTech Connect (OSTI)

The U.S. Department of Energy (DOE) Joint Genome Institute's (JGI) Production Sequencing group is committed to the generation of high-quality genomic DNA sequence to support the mission areas of renewable energy generation, global carbon management, and environmental characterization and clean-up. Within the JGI's Production Sequencing group, a robust Illumina Genome Analyzer and HiSeq pipeline has been established. Optimization of the sesequencer pipelines has been ongoing with the aim of continual process improvement of the laboratory workflow, reducing operational costs and project cycle times to increases ample throughput, and improving the overall quality of the sequence generated. A sequence QC analysis pipeline has been implemented to automatically generate read and assembly level quality metrics. The foremost of these optimization projects, along with sequencing and operational strategies, throughput numbers, and sequencing quality results will be presented.

Daum, Christopher; Zane, Matthew; Han, James; Kennedy, Megan; San Diego, Matthew; Copeland, Alex; Li, Mingkun; Lucas, Susan

2011-01-31T23:59:59.000Z

412

Unraveling life four letters at a time  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

since the official end of the Human Genome Project are fueling a revolution in genomics research. November 25, 2013 Unraveling life four letters at a time Reading the...

413

Evaluation of Project Achievements in VOMARE -project.  

E-Print Network [OSTI]

??The purpose of the thesis is to study the achievements of VOMARE –project from the Finnish Lifeboat Institutions perspective. The organisation is a roof organisation… (more)

Kokkarinen, Eeva

2011-01-01T23:59:59.000Z

414

NEPA COMPLIANCE SURVEY Project Information Project Title:  

Broader source: Energy.gov (indexed) [DOE]

Pollutants? NEPA COMPLIANCE SURVEY Is the project subject to emissions limitations In an Air 0 81 0 Quality Control Region? Impacts If YES, then complete below. Anticipated?...

415

Uses of antimicrobial genes from microbial genome  

DOE Patents [OSTI]

We describe a method for mining microbial genomes to discover antimicrobial genes and proteins having broad spectrum of activity. Also described are antimicrobial genes and their expression products from various microbial genomes that were found using this method. The products of such genes can be used as antimicrobial agents or as tools for molecular biology.

Sorek, Rotem; Rubin, Edward M.

2013-08-20T23:59:59.000Z

416

Genome Biology 2004, 5:343 commentreviewsreportsdepositedresearchinteractionsinformationrefereedresearch  

E-Print Network [OSTI]

://genomebiology.com/2004/5/9/343 © 2004 BioMed Central Ltd A report on the Keystone Symposium `Structural Genomics', held-dollar-plus folly? Two concurrent Keystone Symposia, `Structural Genomics' and `Frontiers in Structural Biology set up an auto- mated pipeline to annotate proteins of known structure but unknown function. The push

417

Genome of Geobacter sulfurreducens: Metal Reduction  

E-Print Network [OSTI]

and in the generation of electricity. G. sulfurreducens, a member of the - Proteobacteria and of the family GeobacterGenome of Geobacter sulfurreducens: Metal Reduction in Subsurface Environments B. A. Methe´,1 * K. Utterback,1 S. E. Van Aken,1 D. R. Lovley,2 C. M. Fraser1 The complete genome sequence of Geobacter

Lovley, Derek

418

The Arabidopsis lyrata genome sequence and the basis of rapid genome size change  

SciTech Connect (OSTI)

In our manuscript, we present a high-quality genome sequence of the Arabidopsis thaliana relative, Arabidopsis lyrata, produced by dideoxy sequencing. We have performed the usual types of genome analysis (gene annotation, dN/dS studies etc. etc.), but this is relegated to the Supporting Information. Instead, we focus on what was a major motivation for sequencing this genome, namely to understand how A. thaliana lost half its genome in a few million years and lived to tell the tale. The rather surprising conclusion is that there is not a single genomic feature that accounts for the reduced genome, but that every aspect centromeres, intergenic regions, transposable elements, gene family number is affected through hundreds of thousands of cuts. This strongly suggests that overall genome size in itself is what has been under selection, a suggestion that is strongly supported by our demonstration (using population genetics data from A. thaliana) that new deletions seem to be driven to fixation.

Hu, Tina T.; Pattyn, Pedro; Bakker, Erica G.; Cao, Jun; Cheng, Jan-Fang; Clark, Richard M.; Fahlgren, Noah; Fawcett, Jeffrey A.; Grimwood, Jane; Gundlach, Heidrun; Haberer, Georg; Hollister, Jesse D.; Ossowski, Stephan; Ottilar, Robert P.; Salamov, Asaf A.; Schneeberger, Korbinian; Spannagl, Manuel; Wang, Xi; Yang, Liang; Nasrallah, Mikhail E.; Bergelson, Joy; Carrington, James C.; Gaut, Brandon S.; Schmutz, Jeremy; Mayer, Klaus F. X.; Van de Peer, Yves; Grigoriev, Igor V.; Nordborg, Magnus; Weigel, Detlef; Guo, Ya-Long

2011-04-29T23:59:59.000Z

419

JGI Genomics and Bioinformatics for Undergraduate Educators Workshop...  

Broader source: Energy.gov (indexed) [DOE]

JGI Genomics and Bioinformatics for Undergraduate Educators Workshop JGI Genomics and Bioinformatics for Undergraduate Educators Workshop March 23, 2013 7:00PM EDT to March 26,...

420

DOE JGI Whole Genome Shotgun Sequencing, part 2  

ScienceCinema (OSTI)

A Howard Hughes Medical Institute (HHMI) video production describing the Whole Genome Shotgun Sequencing process at the US Department of Energy's Joint Genome Institute (JGI).

Miranda Harmon-Smith

2010-09-01T23:59:59.000Z

Note: This page contains sample records for the topic "human genome project" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


421

The Seattle Structure Genomics Center for Infectious Disease...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

The Seattle Structure Genomics Center for Infectious Disease (SSGCID). The Seattle Structure Genomics Center for Infectious Disease (SSGCID). Abstract: The NIAID-funded Seattle...

422

Combining Functional and Structural Genomics to Sample the Essential...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Functional and Structural Genomics to Sample the Essential Burkholderia Structome. Combining Functional and Structural Genomics to Sample the Essential Burkholderia Structome....

423

Comparative Omics-Driven Genome Annotation Refinement: Application...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Abstract: Genome sequencing continues to be a rapidly evolving technology, yet most downstream aspects of genome annotation pipelines remain relatively stable or are even being...

424

SciTech Connect: Multiplex automated genome engineering  

Office of Scientific and Technical Information (OSTI)

Multiplex automated genome engineering Citation Details In-Document Search Title: Multiplex automated genome engineering You are accessing a document from the Department of...

425

aspergillus genome database: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

and avoid outdated data. Heiko Mller 11 Integrative database analysis in structural genomics CiteSeer Summary: Abstract (2 sentences) An important aspect of structural genomics...

426

DOE JGI Whole Genome Shotgun Sequencing, part 3  

ScienceCinema (OSTI)

A Howard Hughes Medical Institute (HHMI) video production describing the Whole Genome Shotgun Sequencing process at the US Department of Energy's Joint Genome Institute (JGI).

Miranda Harmon-Smith

2010-09-01T23:59:59.000Z

427

Functional Genomics of Nervous System Development and Disease .  

E-Print Network [OSTI]

??The goal of functional genomics is to elucidate the relationship between an organism's genotype and phenotype. A key characteristic of functional genomics is the use… (more)

Miller, Michael Ryan

2011-01-01T23:59:59.000Z

428

DOE JGI Whole Genome Shotgun Sequencing, part 1  

ScienceCinema (OSTI)

A Howard Hughes Medical Institute (HHMI) video production describing the Whole Genome Shotgun Sequencing process at the US Department of Energy's Joint Genome Institute (JGI).

Miranda Harmon-Smith

2010-09-01T23:59:59.000Z

429

Comparative genomics analysis of Liberibacter species to elucidate pathogenesis and culturability  

E-Print Network [OSTI]

Vol. 1 (2014) Comparative genomics analysis of Liberibacterof citrus, comparative genomics of this strain with other

Leonard, Michael T.; Fagen, Jennie R.; McCullough, Connor M.; Davis-Richardson, Austin G.; Davis, Michael J.; Triplett, Eric W.

2014-01-01T23:59:59.000Z

430

NSTX Upgrade Project Execution Plan NSTX Upgrade Project  

E-Print Network [OSTI]

NSTX Upgrade Project Execution Plan NSTX Upgrade Project Project Execution Plan National Spherical Torus Experiment (NSTX) Upgrade Project Execution Plan Revision 1 October 6, 2011 Submitted by: R. Strykowsky NSTX Upgrade Project Manager _____________________________ M. Williams Associate Director, PPPL

Princeton Plasma Physics Laboratory

431

NSTX Upgrade Project Execution Plan NSTX Upgrade Project  

E-Print Network [OSTI]

NSTX Upgrade Project Execution Plan NSTX Upgrade Project Project Execution Plan National Spherical Torus Experiment (NSTX) Upgrade Project Execution Plan Revision 3 October 12, 2012 Administrative Change Submitted by: ______________________________ R. Strykowsky NSTX Upgrade Project Manager Anthony Indelicato

Princeton Plasma Physics Laboratory

432

Systematic dissection of regulatory motifs in 2000 predicted human enhancers using a massively parallel reporter assay  

E-Print Network [OSTI]

Genome-wide chromatin annotations have permitted the mapping of putative regulatory elements across multiple human cell types. However, their experimental dissection by directed regulatory motif disruption has remained ...

Kheradpour, Pouya

433

TSINGHUA -MIT China Energy & Climate Project  

E-Print Network [OSTI]

TSINGHUA - MIT China Energy & Climate Project Will economic restructuring in China reduce trade to: discover new interactions among natural and human climate system components; objectively assess future; and improve methods to model, monitor and verify greenhouse gas emissions and climatic impacts

434

Senior projectS corporate Sponsored  

E-Print Network [OSTI]

--Professor, Computer Engineering | http://users.soe.ucsc. edu/~larrabee/Site/Professor_Tracy_Larrabee.html Charlie McSenior projectS program corporate Sponsored Partner's Day May 31, 2012 Baskin School of Engineering earning their engineering degree and fulfilling this capstone design sequence. Our students who have

Stuart, Josh

435

Project Description: page 1 Project Description  

E-Print Network [OSTI]

Project Description: page 1 Project Description I. Introduction: Josephson junction networks Over the past 25 years, superconducting Josephson junctions have gradually become one of the major topics standards. Our research uses Josephson junctions as model systems for problems in nonlinear and neural

Segall, Ken

436

Livingston Campus Geothermal Project The Project  

E-Print Network [OSTI]

Livingston Campus Geothermal Project The Project: Geothermal power is a cost effective, reliable is a Closed Loop Geothermal System involving the removal and storage of approximately four feet of dirt from the entire Geothermal Field and the boring of 321 vertical holes reaching a depth of 500 feet. These holes

Delgado, Mauricio

437

E-Print Network 3.0 - afgd demonstration project Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

11 Department Human Resources Bulletin, 027, FY06, dated August 1,2006 DOC Demonstration Project Operating Procedures Summary: setting pay for Presidential Management Fellows...

438

Genome resequencing in Populus: Revealing large-scale genome variation and implications on specialized-trait genomics  

SciTech Connect (OSTI)

To date, Populus ranks among a few plant species with a complete genome sequence and other highly developed genomic resources. With the first genome sequence among all tree species, Populus has been adopted as a suitable model organism for genomic studies in trees. However, far from being just a model species, Populus is a key renewable economic resource that plays a significant role in providing raw materials for the biofuel and pulp and paper industries. Therefore, aside from leading frontiers of basic tree molecular biology and ecological research, Populus leads frontiers in addressing global economic challenges related to fuel and fiber production. The latter fact suggests that research aimed at improving quality and quantity of Populus as a raw material will likely drive the pursuit of more targeted and deeper research in order to unlock the economic potential tied in molecular biology processes that drive this tree species. Advances in genome sequence-driven technologies, such as resequencing individual genotypes, which in turn facilitates large scale SNP discovery and identification of large scale polymorphisms are key determinants of future success in these initiatives. In this treatise we discuss implications of genome sequence-enable technologies on Populus genomic and genetic studies of complex and specialized-traits.

Muchero, Wellington [ORNL] [ORNL; Labbe, Jessy L [ORNL] [ORNL; Priya, Ranjan [University of Tennessee, Knoxville (UTK)] [University of Tennessee, Knoxville (UTK); DiFazio, Steven P [West Virginia University, Morgantown] [West Virginia University, Morgantown; Tuskan, Gerald A [ORNL] [ORNL

2014-01-01T23:59:59.000Z

439

Proteogenomics : applications of mass spectrometry at the interface of genomics and proteomics  

E-Print Network [OSTI]

of proteomics and genomics to unravel the specificities ofetry and comparative genomics to analyze multiple genomes,”genome,” Comp. Funct. Genomics, vol. 3, no. 3, pp. 244–253,

Castellana, Natalie

2012-01-01T23:59:59.000Z

440

Minipig and beagle animal model genomes aid species selection in pharmaceutical discovery and development  

SciTech Connect (OSTI)

Improving drug attrition remains a challenge in pharmaceutical discovery and development. A major cause of early attrition is the demonstration of safety signals which can negate any therapeutic index previously established. Safety attrition needs to be put in context of clinical translation (i.e. human relevance) and is negatively impacted by differences between animal models and human. In order to minimize such an impact, an earlier assessment of pharmacological target homology across animal model species will enhance understanding of the context of animal safety signals and aid species selection during later regulatory toxicology studies. Here we sequenced the genomes of the Sus scrofa Göttingen minipig and the Canis familiaris beagle, two widely used animal species in regulatory safety studies. Comparative analyses of these new genomes with other key model organisms, namely mouse, rat, cynomolgus macaque, rhesus macaque, two related breeds (S. scrofa Duroc and C. familiaris boxer) and human reveal considerable variation in gene content. Key genes in toxicology and metabolism studies, such as the UGT2 family, CYP2D6, and SLCO1A2, displayed unique duplication patterns. Comparisons of 317 known human drug targets revealed surprising variation such as species-specific positive selection, duplication and higher occurrences of pseudogenized targets in beagle (41 genes) relative to minipig (19 genes). These data will facilitate the more effective use of animals in biomedical research. - Highlights: • Genomes of the minipig and beagle dog, two species used in pharmaceutical studies. • First systematic comparative genome analysis of human and six experimental animals. • Key drug toxicology genes display unique duplication patterns across species. • Comparison of 317 drug targets show species-specific evolutionary patterns.

Vamathevan, Jessica J., E-mail: jessica.j.vamathevan@gsk.com [Computational Biology, Quantitative Sciences, GlaxoSmithKline, Stevenage (United Kingdom); Hall, Matthew D.; Hasan, Samiul; Woollard, Peter M. [Computational Biology, Quantitative Sciences, GlaxoSmithKline, Stevenage (United Kingdom); Xu, Meng; Yang, Yulan; Li, Xin; Wang, Xiaoli [BGI-Shenzen, Shenzhen (China); Kenny, Steve [Safety Assessment, PTS, GlaxoSmithKline, Ware (United Kingdom); Brown, James R. [Computational Biology, Quantitative Sciences, GlaxoSmithKline, Collegeville, PA (United States); Huxley-Jones, Julie [UK Platform Technology Sciences (PTS) Operations and Planning, PTS, GlaxoSmithKline, Stevenage (United Kingdom); Lyon, Jon; Haselden, John [Safety Assessment, PTS, GlaxoSmithKline, Ware (United Kingdom); Min, Jiumeng [BGI-Shenzen, Shenzhen (China); Sanseau, Philippe [Computational Biology, Quantitative Sciences, GlaxoSmithKline, Stevenage (United Kingdom)

2013-07-15T23:59:59.000Z

Note: This page contains sample records for the topic "human genome project" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


441

The Science and Issues of Human DNA Polymorphisms: A Training Workshop for High School Biology Teachers  

SciTech Connect (OSTI)

This project achieved its goal of implementing a nationwide training program to introduce high school biology teachers to the key uses and societal implications of human DNA polymorphisms. The 2.5-day workshop introduced high school biology faculty to a laboratory-based unit on human DNA polymorphisms â�� which provides a uniquely personal perspective on the science and Ethical, Legal and Social Implications (ELSI) of the Human Genome Project. As proposed, 12 workshops were conducted at venues across the United States. The workshops were attended by 256 high school faculty, exceeding proposed attendance of 240 by 7%. Each workshop mixed theoretical, laboratory, and computer work with practical and ethical implications. Program participants learned simplified lab techniques for amplifying three types of chromosomal polymorphisms: an Alu insertion (PV92), a VNTR (pMCT118/D1S80), and single nucleotide polymorphisms (SNPs) in the mitochondrial control region. These polymorphisms illustrate the use of DNA variations in disease diagnosis, forensic biology, and identity testing - and provide a starting point for discussing the uses and potential abuses of genetic technology. Participants also learned how to use their Alu and mitochondrial data as an entr�©e to human population genetics and evolution. Our work to simplify lab techniques for amplifying human DNA polymorphisms in educational settings culminated with the release in 1998 of three Advanced Technology (AT) PCR kits by Carolina Biological Supply Company, the nationâ��s oldest educational science supplier. The kits use a simple 30-minute method to isolate template DNA from hair sheaths or buccal cells and streamlined PCR chemistry based on Pharmacia Ready-To-Go Beads, which incorporate Taq polymerase, deoxynucleotide triphosphates, and buffer in a freeze-dried pellet. These kits have greatly simplified teacher implementation of human PCR labs, and their use is growing at a rapid pace. Sales of human polymorphism kits by Carolina Biological rose from 700 units in 1999 to 1,132 in 2000 â�� a 62% increase. Competing kits using the Alu system, and based substantially on our earlier work, are also marketed by Biorad and Edvotek. In parallel with the lab experiments, we developed a suite of database/statistical applications and easy-to-use interfaces that allow students to use their own DNA data to explore human population genetics and to test theories of human evolution. Database searches and statistical analyses are launched from a centralized workspace. Workshop participants were introduced to these and other resources available at the DNALC WWW site (http://vector.cshl.org/bioserver/): 1) Allele Server tests Hardy-Weinberg equilibrium and statistically compares PV92 data from world populations. 2) Sequence Server uses DNA sequence data to search Genbank using BLASTN, compare sequences using CLUSTALW, and create phylogenetic trees using PHYLIP. 3) Simulation Server uses a Monte Carlo generator to model the long-term effects of drift, selection, and population bottlenecks. By targeting motivated and innovative biology faculty, we believe that this project offered a cost-effective means to bring high school biology education up-to-the-minute with genomic biology. The workshop reached a target audience of highly professional faculty who have already implemented hands-on labs in molecular genetics and many of whom offer laboratory electives in biotechnology. Many attend professional meetings, develop curriculum, collaborate with scientists, teach faculty workshops, and manage equipment-sharing programs. These individuals are life-long learners, anxious for deeper insight and additional training to further extend their leadership. This contention was supported by data from a mail survey, conducted in February-March 2000 and 2001, of 256 faculty who participated in workshops conducted during the current term of DOE support. Seventy percent of participants responded, providing direct reports on how their teaching behavi

David A. Micklos

2006-10-30T23:59:59.000Z

442

Genome Sequence of the Palaeopolyploid soybean  

SciTech Connect (OSTI)

Soybean (Glycine max) is one of the most important crop plants for seed protein and oil content, and for its capacity to fix atmospheric nitrogen through symbioses with soil-borne microorganisms. We sequenced the 1.1-gigabase genome by a whole-genome shotgun approach and integrated it with physical and high-density genetic maps to create a chromosome-scale draft sequence assembly. We predict 46,430 protein-coding genes, 70percent more than Arabidopsis and similar to the poplar genome which, like soybean, is an ancient polyploid (palaeopolyploid). About 78percent of the predicted genes occur in chromosome ends, which comprise less than one-half of the genome but account for nearly all of the genetic recombination. Genome duplications occurred at approximately 59 and 13 million years ago, resulting in a highly duplicated genome with nearly 75percent of the genes present in multiple copies. The two duplication events were followed by gene diversification and loss, and numerous chromosome rearrangements. An accurate soybean genome sequence will facilitate the identification of the genetic basis of many soybean traits, and accelerate the creation of improved soybean varieties.

Schmutz, Jeremy; Cannon, Steven B.; Schlueter, Jessica; Ma, Jianxin; Mitros, Therese; Nelson, William; Hyten, David L.; Song, Qijian; Thelen, Jay J.; Cheng, Jianlin; Xu, Dong; Hellsten, Uffe; May, Gregory D.; Yu, Yeisoo; Sakura, Tetsuya; Umezawa, Taishi; Bhattacharyya, Madan K.; Sandhu, Devinder; Valliyodan, Babu; Lindquist, Erika; Peto, Myron; Grant, David; Shu, Shengqiang; Goodstein, David; Barry, Kerrie; Futrell-Griggs, Montona; Abernathy, Brian; Du, Jianchang; Tian, Zhixi; Zhu, Liucun; Gill, Navdeep; Joshi, Trupti; Libault, Marc; Sethuraman, Anand; Zhang, Xue-Cheng; Shinozaki, Kazuo; Nguyen, Henry T.; Wing, Rod A.; Cregan, Perry; Specht, James; Grimwood, Jane; Rokhsar, Dan; Stacey, Gary; Shoemaker, Randy C.; Jackson, Scott A.

2009-08-03T23:59:59.000Z

443

Contract/Project Management  

Broader source: Energy.gov (indexed) [DOE]

and Targets 1 ContractProject Management Performance Metric FY 2012 Target FY 2012 Forecast FY 2012 Pre- & Post-CAP Forecast Comment Capital Asset Project Success: Complete 90%...

444

Contract/Project Management  

Energy Savers [EERE]

on a 3-year rolling average (FY09 to FY11). TPC is Total Project Cost. 2a. EM Cleanup (Soil and Groundwater Remediation, D&D, and Waste Treatment and Disposal) Projects: (Pre-...

445

Rank Project Name Directorate,  

E-Print Network [OSTI]

Rank Project Name Directorate, Dept/Div and POC Cost Savings Payback (Years) Waste Reduction 1 NATIONAL LABORATORY FY02 Funded Pollution Prevention Projects 0.4 Years (~5 months) #12;

446

The 4-H Project  

E-Print Network [OSTI]

As a 4-H volunteer, you will find that projects are useful tools for teaching a wide variety of skills to young people. This publication will help you plan and evaluate 4-H learning projects....

Howard, Jeff W.

2005-05-10T23:59:59.000Z

447

Information Technology Project Management  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

The Order provides program and project management direction for the acquisition and management of IT projects, investments, and initiatives. Cancels DOE G 200.1-1. Admin Chg 1 approved 1-16-2013.

2012-12-03T23:59:59.000Z

448

Planning the Project Meeting  

E-Print Network [OSTI]

Project group meetings must be planned well in advance. Members should be involved in completing some type of work before the next meeting. This helps the leader plan the next project meeting and makes efficient use of time....

Howard, Jeff W.

2005-05-10T23:59:59.000Z

449

Information Technology Project Management  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

The Order provides program and project management direction for the acquisition and management of IT projects, investments, and initiatives. Cancels DOE G 200.1-1. Admin Chg 1, dated 1-16-2013, cancels DOE O 415.1.

2012-12-03T23:59:59.000Z

450

Page 1 of 26 INDEPENDENT PROJECT  

E-Print Network [OSTI]

Page 1 of 26 INDEPENDENT PROJECT EVALUATION PROJECT NAME: HIVE PROOF-OF- CONCEPT PROJECT PROJECT ............................................................................................................................................3 The Project..............................................................................................................................................3 Project Objectives and Achievements

Evans, Paul

451

NSTX Upgrade Project Execution Plan NSTX Upgrade Project  

E-Print Network [OSTI]

#12;#12;NSTX Upgrade Project Execution Plan NSTX Upgrade Project Project Execution Plan i Record;NSTX Upgrade Project Execution Plan NSTX Upgrade Project Project Execution Plan ii Table of Contents 1 ..............................................................................................................................1 1.2.1 DOE-approved project documents

Princeton Plasma Physics Laboratory

452

NSTX Upgrade Project Execution Plan NSTX Upgrade Project  

E-Print Network [OSTI]

#12;NSTX Upgrade Project Execution Plan NSTX Upgrade Project Project Execution Plan i Record/schedule baseline updates #12;NSTX Upgrade Project Execution Plan NSTX Upgrade Project Project Execution Plan ii ..............................................................................................................................1 1.2.1 DOE-approved project documents

Princeton Plasma Physics Laboratory

453

WIPP Projects Interative Map  

Broader source: Energy.gov [DOE]

View WIPP Projects in a larger map. To report corrections, please email WeatherizationInnovation@ee.doe.gov.

454

GHPsRUS Project  

DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

The GHPsRUS Project's full name is "Measuring the Costs and Benefits of Nationwide Geothermal Heat Pump Deployment." The dataset contains employment and installation price data collected by four economic surveys: (1)GHPsRUS Project Manufacturer & OEM Survey, (2) GHPsRUS Project Geothermal Loop Survey, (3) GHPsRUS Project Mechanical Equipment Installation Survey, and (4) GHPsRUS Geothermal Heat Pump Industry Survey

Battocletti, Liz

455

GHPsRUS Project  

SciTech Connect (OSTI)

The GHPsRUS Project's full name is "Measuring the Costs and Benefits of Nationwide Geothermal Heat Pump Deployment." The dataset contains employment and installation price data collected by four economic surveys: (1)GHPsRUS Project Manufacturer & OEM Survey, (2) GHPsRUS Project Geothermal Loop Survey, (3) GHPsRUS Project Mechanical Equipment Installation Survey, and (4) GHPsRUS Geothermal Heat Pump Industry Survey

Battocletti, Liz

2013-07-09T23:59:59.000Z

456

Project: BELLA Bldg. #: 71  

E-Print Network [OSTI]

: BEVATRON Bldg. #: 51 Affected Area: Lot I (6) Lower Lot (52) Dates: 6/2009 - 11/2011 Project: Seismic PhaseProject: BELLA Bldg. #: 71 Affected Area: Lot M-1(12) B81 (18) Dates: 10/2010 ­ 10/2011 Project II Bldg. #: 74 Affected Area: U1 (50) U3 (21) Dates: 10/2009 ­ 4/2012 Project: Old Town Demo Bldg

457

Automatic annotation of organellar genomes with DOGMA  

SciTech Connect (OSTI)

Dual Organellar GenoMe Annotator (DOGMA) automates the annotation of extra-nuclear organellar (chloroplast and animal mitochondrial) genomes. It is a web-based package that allows the use of comparative BLAST searches to identify and annotate genes in a genome. DOGMA presents a list of putative genes to the user in a graphical format for viewing and editing. Annotations are stored on our password-protected server. Complete annotations can be extracted for direct submission to GenBank. Furthermore, intergenic regions of specified length can be extracted, as well the nucleotide sequences and amino acid sequences of the genes.

Wyman, Stacia; Jansen, Robert K.; Boore, Jeffrey L.

2004-06-01T23:59:59.000Z

458

Genome Engineering with TAL Effector Nucleases  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation ProposedUsingFun with Big Sky Learning Fun withGenepoolCrystals. |GenericGenomeGenomeGenome

459

Intercellular Genomics of Subsurface Microbial Colonies  

SciTech Connect (OSTI)

This report summarizes progress in the second year of this project. The objective is to develop methods and software to predict the spatial configuration, properties and temporal evolution of microbial colonies in the subsurface. To accomplish this, we integrate models of intracellular processes, cell-host medium exchange and reaction-transport dynamics on the colony scale. At the conclusion of the project, we aim to have the foundations of a predictive mathematical model and software that captures the three scales of these systems – the intracellular, pore, and colony wide spatial scales. In the second year of the project, we refined our transcriptional regulatory network discovery (TRND) approach that utilizes gene expression data along with phylogenic similarity and gene ontology analyses and applied it successfully to E.coli, human B cells, and Geobacter sulfurreducens. We have developed a new Web interface, GeoGen, which is tailored to the reconstruction of microbial TRNs and solely focuses on Geobacter as one of DOE’s high priority microbes. Our developments are designed such that the frameworks for the TRND and GeoGen can readily be used for other microbes of interest to the DOE. In the context of modeling a single bacterium, we are actively pursuing both steady-state and kinetic approaches. The steady-state approach is based on a flux balance that uses maximizing biomass growth rate as its objective, subjected to various biochemical constraints, for the optimal values of reaction rates and uptake/release of metabolites. For the kinetic approach, we use Karyote, a rigorous cell model developed by us for an earlier DOE grant and the DARPA BioSPICE Project. We are also investigating the interplay between bacterial colonies and environment at both pore and macroscopic scales. The pore scale models use detailed representations for realistic porous media accounting for the distribution of grain size whereas the macroscopic models employ the Darcy-type flow equations and up-scaled advective-diffusive transport equations for chemical species. We are rigorously testing the relationship between these two scales by evaluating macroscopic parameters using the volume averaging methodology applied to pore scale model results.

Ortoleva, Peter; Tuncay, Kagan; Gannon, Dennis; Meile, Christof

2007-02-14T23:59:59.000Z

460

Fundamental Aeronautics Hypersonics Project  

E-Print Network [OSTI]

Fundamental Aeronautics Hypersonics Project Reference Document Principal Investigator: James and detailed content of a comprehensive Fundamental Aeronautics Hypersonics research project. It contains) Hypersonic Project is based on the fact that all access to earth or planetary orbit, and all entry into earth

Note: This page contains sample records for the topic "human genome project" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


461

Project Website Information Architecture  

E-Print Network [OSTI]

Project Website Information Architecture Overview Purpose: To describe up front what your initiative/project does. This section does not need to literally be called "Overview;" you can come up with anther suitable title that is more specific to your project. Examples of what to include: Information

462

Project Scheduling (3) Corequisite  

E-Print Network [OSTI]

) CMGT 111 Construction Materials & Methods Lab (1) CMGT 460 Project Cost Controls (3) FA SP CMGT 320 FASYMBOLS CMGT 417 Project Scheduling (3) Corequisite Offered FALL Only CMGT 240 Intro) CMGT 475 Construction Project Management (3) MATH 108 College Algebra (4) Construction Elective

Barrash, Warren

463

Project Scheduling (3) Corequisite  

E-Print Network [OSTI]

460 Project Cost Controls (3) FA SP FA CE 210/211 Surveying & Lab (3) CMGT 410 Concrete FormworkSYMBOLS CMGT 417 Project Scheduling (3) Corequisite Offered FALL Only CMGT 240 Intro Construction Project Management (3) MATH 108 College Algebra (4) MGMT 301 Leadership Skills (3) ENGL 101

Barrash, Warren

464

New Project Opportunities  

E-Print Network [OSTI]

/year. Most projects will be sponsored by between four and ten companies. The cost of participation may changeNew Project Opportunities PIMS: Porphyry Indicator Minerals The characteristics and relative, the next phase of this project has started and MDRU are looking for industry partners. Exploring Lithocaps

Michelson, David G.

465

Kansas Advanced Semiconductor Project  

SciTech Connect (OSTI)

KASP (Kansas Advanced Semiconductor Project) completed the new Layer 0 upgrade for D0, assumed key electronics projects for the US CMS project, finished important new physics measurements with the D0 experiment at Fermilab, made substantial contributions to detector studies for the proposed e+e- international linear collider (ILC), and advanced key initiatives in non-accelerator-based neutrino physics.

Baringer, P.; Bean, A.; Bolton, T.; Horton-Smith, G.; Maravin, Y.; Ratra, B.; Stanton, N.; von Toerne, E.; Wilson, G.

2007-09-21T23:59:59.000Z

466

APPLIED GENOMICS TECHNOLOGY CENTER www.agtc.med.wayne.edu  

E-Print Network [OSTI]

APPLIED GENOMICS TECHNOLOGY CENTER www.agtc.med.wayne.edu CURRENT SERVICES CONTACT INFORMATION Dr. Susan J. Land, Ph.D. Laboratory Director ABOUT THE FACILITY The Applied Genomics Technology Center (AGTC-of-the-art, fee-for-service genomics center that provides a wide range of genomic technologies to the medical

Berdichevsky, Victor

467

Functional Genomics: It's All How You Read It  

E-Print Network [OSTI]

Functional Genomics: It's All How You Read It Philip Hieter and Mark Boguski "Functional genomics to functional genomics? An informal poll of colleagues indicates that the term is widely used, but has many genomics websites that have sprung up over the last 12 months clearly demonstrates that interpretations

Boguski, Mark S.

468

THE CAMPAIGN FOR UC SANTA CRUZ THE GENOMICS  

E-Print Network [OSTI]

THE CAMPAIGN FOR UC SANTA CRUZ THE GENOMICS INSTITUTE #12;OVERVIEW The UC Santa Cruz Genomics Institute provides the framework for the next great leap in the science of genomics. ensured it would genomic science and speed the benefits of discoveries that improve and save lives. Cancer, autoimmune

California at Santa Cruz, University of

469

Phylogenetics of modern birds in the era of genomics  

E-Print Network [OSTI]

Review Phylogenetics of modern birds in the era of genomics Scott V. Edwards*, W. Bryan Jennings and maturation of the genomics era, the completion of the chicken genome and a suite of technologies that promise genomics strategies, including adoption of objective quality scores for sequence data, analysis

Edwards, Scott

470

Target selection and current status of structural genomics for the  

E-Print Network [OSTI]

33 Target selection and current status of structural genomics for the completed microbial genomes 3.2 Structural status of completed microbial genomes in the PDB................ 3.3 Metabolic pathways as targets for structural genomics.......................... 3.3.1 Glycolytic pathway

Babu, M. Madan

471

An Integrated Program in Microbial Genome Sequencing and Analysis  

SciTech Connect (OSTI)

Under this award, numerous genome sequences were generated, analyzed, published and made publicly available.

Claire M. Fraser, Ph.D.; J.E. Eisen, Ph.D.; W. Nierman, Ph.D.; K. Nelson, Ph.D.; H. Tettelin, Ph.D.; J. Heidelberg, Ph.D.; O. White, Ph.D.; B. Methe, Ph.D.; N. El-Sayed, Ph.D.; S. Gill, Ph.D.; S. Peterson, Ph.D.; J. Quackenbush, Ph.D.; T. Read, Ph.D.

2005-11-30T23:59:59.000Z

472

Letter to the Editor Toward Sequencing Cotton (Gossypium) Genomes  

E-Print Network [OSTI]

Letter to the Editor Toward Sequencing Cotton (Gossypium) Genomes Despite rapidly decreasing costs complex ge- nomes de novo. The cotton (Gossypium spp.) genomes represent a challenging case. To this end, a coalition of cotton genome scientists has developed a strategy for sequencing the cotton genomes, which

Chee, Peng W.

473

Product Guide Project Standard and Project Professional  

E-Print Network [OSTI]

................................................................................................................................................................6 Manage Projects and Programs, or other intellectual property that are the subject matter of this document. #12;Table of Contents .......................................................................................................9 Make It Yours ­ Personalize the Ribbon

Narasayya, Vivek

474

Project Overload in Project Based Organizations - Causes, Symptoms and Effects.  

E-Print Network [OSTI]

?? This study investigates the matter of project overload which project members have to face in project based organizations. The thesis is based on 13… (more)

Hochdorfer, Tobias

2007-01-01T23:59:59.000Z

475

Accelerating Biofuel Feedstock Crop Improvement with Miscanthus Genomics (2014 DOE JGI Genomics of Energy & Environment Meeting)  

SciTech Connect (OSTI)

Kankshita Swaminathan of the Energy Biosciences Institute speaks at the 9th Annual Genomics of Energy & Environment Meeting on March 20, 2014 in Walnut Creek, Calif.

Swaminathan, Kankshita [Energy Biosciences Institute

2014-03-20T23:59:59.000Z

476

Application of comparative genomics for detection of genomic features and transcriptional regulatory elements.  

E-Print Network [OSTI]

??In the wake of advanced DNA sequencing technology, a large number of bacterial, animal, and plant genomes have now been completely sequenced and deposited into… (more)

Lu, Hong

2011-01-01T23:59:59.000Z

477

THESIS PROJECT: REGISTRATION NOTE!! The form is to be handed in to the thesis project coordinator, see www.it.uu.se/edu/exjobb  

E-Print Network [OSTI]

1 (2) THESIS PROJECT: REGISTRATION NOTE!! The form is to be handed in to the thesis project of Information Technology Study Program: CS HCI SC ES Other (CS=Computer Science, HCI=Human-Computer Interaction: ............................................................................................................................................................................. ................................................................................................................................... The project will be carried out

Andersson, Arne

478

Performance Comparison of Two Genome Partitioning Platforms  

SciTech Connect (OSTI)

Jon Armstrong from the Genome Center at Washington University in St. Louis School of Medicine speaks at the "Sequencing, Finishing, Analysis in the Future" meeting in Santa Fe, NM

Armstrong, Joe [Genome Center at Washington University in St. Louis School of Medicine

2009-05-29T23:59:59.000Z

479

Computational regulatory genomics : motifs, networks, and dynamics  

E-Print Network [OSTI]

Gene regulation, the process responsible for taking a static genome and producing the diversity and complexity of life, is largely mediated through the sequence specific binding of regulators. The short, degenerate nature ...

Kheradpour, Pouya

2012-01-01T23:59:59.000Z

480

Next-generation information systems for genomics   

E-Print Network [OSTI]

The advent of next-generation sequencing technologies is transforming biology by enabling individual researchers to sequence the genomes of individual organisms or cells on a massive scale. In order to realize the ...

Mungall, Christopher

2011-06-27T23:59:59.000Z

Note: This page contains sample records for the topic "human genome project" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


481

Prokaryotic Genomes from Microbes Online Database  

DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

To describe the potential functions of genes, MicrobesOnline includes protein family analyses (from InterPro and COG), metabolic maps (from KEGG), links to research papers (from UniProt and PubMed), and operon predictions for every genome. To examine each gene's evolutionary history, MicrobesOnline includes precomputed phylogenetic trees for all the gene families. It displays gene trees with genomic context or it compares the gene tree to the species tree. The tools provided with MicrobesOnline allow users to: compute customized motifs, sequence alignments, and phylogenetic trees change expression patterns in metabolic maps annotate genes in various ways The database contains more than 430 genomes. A browse tree tool and a genome browser are available, along with specialized search capabilities. (Specialized Interface)

Alm, Eric J.; Huang, Katherine H.; Price, Morgan N.; Koche, Richard P.; Keller, Keith; Dubchak, Inna L.; Arkin, Adam P.

482

Comparative genomics and bioenergetics Jose Castresana *  

E-Print Network [OSTI]

Review Comparative genomics and bioenergetics Jose Castresana * European Molecular Biology conclusions about the phylogenetic distribution and evolution of bioenergetic pathways to be drawn conservation used by prokaryotes. In addition, a thorough phylogenetic analysis of other bioenergetic protein

Castresana, Jose

483

Cancer Vulnerabilities Unveiled by Genomic Loss  

E-Print Network [OSTI]

Due to genome instability, most cancers exhibit loss of regions containing tumor suppressor genes and collateral loss of other genes. To identify cancer-specific vulnerabilities that are the result of copy number losses, ...

Nijhawan, Deepak

484

Genomic aggregation effects and Simpson's paradox  

E-Print Network [OSTI]

Genomic studies have become commonplace, with thousands of gene expressions typically collected on single or multiple platforms and analyzed. Unaccounted time-ordered or epigenetic aspects of genetic expression may lead ...

Brimacombe, Michael

2014-01-08T23:59:59.000Z

485

DOE Joint Genome Institute 2008 Progress Report  

E-Print Network [OSTI]

Genomics of cellulosic biofuels. Nature, 454 (7206):841-845,2008 Termite Bellies and Biofuels (Published in Smithsonian,in the quest for viable biofuels. An estimated 10,000 marine

Gilbert, David

2009-01-01T23:59:59.000Z

486

Computational Genomics c Ron Shamir  

E-Print Network [OSTI]

proteins which are longer than 100 aa. Perform a BLAST (www.ncbi.nih.gov/BLAST) search with each of the predicted proteins against the non-redundant (nr) database in human. For each Blast outcome, report the best of reasoning called explaining away, in the presence of an effect, infor- mation about one cause can change our

Beimel, Amos

487

1st Genomics-Bioinformatics Day on "Comparative Genomics" April 24th 2003 in the Medawar Building in the  

E-Print Network [OSTI]

1st Genomics-Bioinformatics Day on "Comparative Genomics" April 24th 2003 in the Medawar Building. There is a need, however, for researchers interested in genomics and bioinformatics to meet, so Jotun Hein, Richard Mott and Chris Ponting have organised the first Genomics/Bioinformatics day. It is our intention

Goldschmidt, Christina

488

The Plant Genome [A Supplement to Crop Science] March 2008 No. 1 S-27 Genomic Origins of Potato  

E-Print Network [OSTI]

The Plant Genome [A Supplement to Crop Science] March 2008 No. 1 S-27 Genomic Origins of Potato., and Shelley H. Jansky Abstract Chromosome pairing relationships within cultivated potato (Solanum tuberosum we reexamine potato genome hypotheses with the first phylogenetic analysis of all major genomes

Spooner, David

489

DIGITAL ARCHITECTURE PROJECT PLAN  

SciTech Connect (OSTI)

The objective of this project is to develop an industry consensus document on how to scope and implement the underlying information technology infrastructure that is needed to support a vast array of real-time digital technologies to improve NPP work efficiency, to reduce human error, to increase production reliability and to enhance nuclear safety. A consensus approach is needed because: • There is currently a wide disparity in nuclear utility perspectives and positions on what is prudent and regulatory-compliant for introducing certain digital technologies into the plant environment. For example, there is a variety of implementation policies throughout the industry concerning electromagnetic compatibility (EMC), cyber security, wireless communication coverage, mobile devices for workers, mobile technology in the control room, and so forth. • There is a need to effectively share among the nuclear operating companies the early experience with these technologies and other forms of lessons-learned. There is also the opportunity to take advantage of international experience with these technologies. • There is a need to provide the industry with a sense of what other companies are implementing, so that each respective company can factor this into their own development plans and position themselves to take advantage of new work methods as they are validated by the initial implementing companies. In the nuclear power industry, once a better work practice has been proven, there is a general expectation that the rest of the industry will adopt it. However, the long-lead time of information technology infrastructure could prove to be a delaying factor. A secondary objective of this effort is to provide a general understanding of the incremental investment that would be required to support the targeted digital technologies, in terms of an incremental investment over current infrastructure. This will be required for business cases to support the adoption of these new technologies.

Thomas, Ken

2014-09-01T23:59:59.000Z

490

The Genomes OnLine Database (GOLD) v.4: status of genomic and metagenomic projects and their associated metadata  

E-Print Network [OSTI]

new   metagenome   advanced   search  option  under  the  “available.     2.  “ Advanced  Search”,  where  the  extra  in    GOLD’s  advanced  search  engine,  graphical  

Pagani, Ioanna

2012-01-01T23:59:59.000Z

491

Cheminformatics for genome-scale metabolic reconstructions  

E-Print Network [OSTI]

.15 Problematic tetrahedral stereocentres . . . . . . . . . . . . . . . . . . . . . 190 6.16 Corrupting stereochemistry depiction . . . . . . . . . . . . . . . . . . . . 192 6.17 Variable CIP descriptors of myo-inositol using JChem . . . . . . . . . . . 193 6... of Biological Interest CIP Cahn-Ingold-Prelog EC Enzyme Commission GEM Genome-scale metabolic model GPR Gene-Protein-Reaction InChI IUPAC International Chemical Identifier KEGG Kyoto Encyclopedia of Genes and Genomes MIRIAM Minimum Information Required...

May, John W.

2015-01-06T23:59:59.000Z

492

Renewable Energy Project Refinement Webinar  

Broader source: Energy.gov [DOE]

Attendees will become familiar with the three components of project refinement: project financing strategies, off-taker agreements, and vendor selection. Project refinement obstacles, particularly...

493

RENOTER Project | Department of Energy  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

RENOTER Project RENOTER Project Overview of French project on thermoelectric waste heat recovery for cars and trucks with focus on cheap, available, efficient, and sustainable TE...

494

A computer system for access to distributed genome mapping data  

SciTech Connect (OSTI)

Development of a computer system for access to distributed genome mapping data is continuing. This effort is to develop software which accesses multiple databases and retrieves data which contain information useful for accelerating mapping human chromosomes. For example, the molecular sequence databases (GenBank, EMBL Data Library, PIR, SwissProt) which contain data required for the development of oligonucleotides for probing DNA as well as for extracting data for primer pair development for PCR-based methods. It is also to develop software which qualitatively integrates the following mapping data: (1) markers regionally localized using cytogenetic methods, (2) polymorphic markers ordered by genetic linkage analysis, (3) clones ordered by various finger-printing'' methods, (4) fragments ordered by long-range restriction mapping, (5) single genomic fragments or clones that have STSs assigned to them, (6) nucleotide sequences, (7) the associated metadata such as the submitting investigator's name, location, etc; the source organism; the chromosome the element is from; the chromosomal location is whatever detail is available.

Marr, T.G.

1992-02-05T23:59:59.000Z

495

BEACON SOLAR ENERGY PROJECT (08-AFC-2) Project Title: Beacon Solar Energy Project (Beacon)  

E-Print Network [OSTI]

BEACON SOLAR ENERGY PROJECT (08-AFC-2) FACT SHEET Project Title: Beacon Solar Energy Project and operate the Beacon Solar Energy Project (Beacon). Location: The project is located in eastern Kern County;BEACON SOLAR ENERGY PROJECT (08-AFC-2) FACT SHEET Licensing: The Beacon project would have a nominal

496

National Compact Stellarator Experiment Project Closeout Report PROJECT CLOSEOUT REPORT  

E-Print Network [OSTI]

National Compact Stellarator Experiment Project Closeout Report i PROJECT CLOSEOUT REPORT NATIONAL of Science Princeton Plasma Physics Laboratory Oak Ridge National Laboratory #12;National Compact Stellarator Experiment Project Closeout Report PROJECT CLOSEOUT REPORT NATIONAL COMPACT STELLARATOR EXPERIMENT (NCSX

Princeton Plasma Physics Laboratory

497

NSTX Upgrade Project Execution Plan NSTX Upgrade Project  

E-Print Network [OSTI]

#12;NSTX Upgrade Project Execution Plan NSTX Upgrade Project Project Execution Plan i Record 10/12/2012 Update to WBS Level 2 Threshold (top of page 20), Change DOE Federal Project Director and Deputy Federal Project Director. Various OBS changes. #12;NSTX Upgrade Project Execution Plan NSTX

Princeton Plasma Physics Laboratory

498

The CHPRC Columbia River Protection Project Quality Assurance Project Plan  

SciTech Connect (OSTI)

Pacific Northwest National Laboratory researchers are working on the CHPRC Columbia River Protection Project (hereafter referred to as the Columbia River Project). This is a follow-on project, funded by CH2M Hill Plateau Remediation Company, LLC (CHPRC), to the Fluor Hanford, Inc. Columbia River Protection Project. The work scope consists of a number of CHPRC funded, related projects that are managed under a master project (project number 55109). All contract releases associated with the Fluor Hanford Columbia River Project (Fluor Hanford, Inc. Contract 27647) and the CHPRC Columbia River Project (Contract 36402) will be collected under this master project. Each project within the master project is authorized by a CHPRC contract release that contains the project-specific statement of work. This Quality Assurance Project Plan provides the quality assurance requirements and processes that will be followed by the Columbia River Project staff.

Fix, N. J.

2008-11-30T23:59:59.000Z

499

Battleground Energy Recovery Project  

SciTech Connect (OSTI)

In October 2009, the project partners began a 36-month effort to develop an innovative, commercial-scale demonstration project incorporating state-of-the-art waste heat recovery technology at Clean Harbors, Inc., a large hazardous waste incinerator site located in Deer Park, Texas. With financial support provided by the U.S. Department of Energy, the Battleground Energy Recovery Project was launched to advance waste heat recovery solutions into the hazardous waste incineration market, an area that has seen little adoption of heat recovery in the United States. The goal of the project was to accelerate the use of energy-efficient, waste heat recovery technology as an alternative means to produce steam for industrial processes. The project had three main engineering and business objectives: Prove Feasibility of Waste Heat Recovery Technology at a Hazardous Waste Incinerator Complex; Provide Low-cost Steam to a Major Polypropylene Plant Using Waste Heat; and ï?· Create a Showcase Waste Heat Recovery Demonstration Project.

Daniel Bullock

2011-12-31T23:59:59.000Z

500

Integrated Microbial Genomes (IMG) System from the DOE Joint Genome Institute (JGI)  

DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

The integrated microbial genomes (IMG) system is a data management, analysis and annotation platform for all publicly available genomes. IMG contains both draft and complete JGI microbial genomes integrated with all other publicly available genomes from all three domains of life, together with a large number of plasmids and viruses. IMG provides tools and viewers for analyzing and annotating genomes, genes and functions, individually or in a comparative context. Since its first release in 2005, IMG's data content and analytical capabilities have been constantly expanded through quarterly releases. IMG is provided by the DOE-Joint Genome Institute (JGI) and is available from http://img.jgi.doe.gov. [Abstract from The integrated microbial genomes (IMG) system in 2007: data content and analysis tool extensions; Victor M. Markowitz, Ernest Szeto, Krishna Palaniappan, Yuri Grechkin, Ken Chu, I-Min A. Chen, Inna Dubchak, Iain Anderson, Athanasios Lykidis, Konstantinos Mavromatis, Natalia N. Ivanova and Nikos C. Kyrpides; Nucleic Acids Research, 2008, Vol. 36. (Database Issue) See also the companion system, Integrated Microbial Genomes with Microbiome Samples.