Sample records for hospital chronic disease

  1. Interim Chronic Beryllium Disease

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1999-12-08T23:59:59.000Z

    Establishes Departmental expectations for addressing chronic beryllium disease throughout the Department until a Departmental rule on beryllium is promulgated. This Notice was replaced by final rule 10 CFR Part 850, Chronic Beryllium Disease Prevention Program, published December 8, 1999.

  2. Chronic Conditions and Disease Prevention

    E-Print Network [OSTI]

    , diabetes, heart disease and osteoarthritis. One-on-One Nutrition Counseling Help with weight management and supportive program for those who have chronic diseases such as diabetes, heart disease, stroke, arthritis

  3. Chronic beryllium disease: Diagnosis and management

    SciTech Connect (OSTI)

    Rossman, M.D. [Hospital of the Univ. of Pennsylvania, Philadelphia, PA (United States)

    1996-10-01T23:59:59.000Z

    Chronic beryllium disease is predominantly a pulmonary granulomatosis that was originally described in 1946. Symptoms usually include dyspnea and cough. Fever, anorexia, and weight loss are common. Skin lesions are the most common extrathoracic manifestation. Granulomatous hepatitis, hypercalcemia, and kidney stones can also occur. Radiographic and physiologic abnormalities are similar to those in sarcoidosis. While traditionally the pathologic changes included granulomas and cellular interstitial changes, the hallmark of the disease today is the well-formed granuloma. Immunologic studies have demonstrated a cell-mediated response to beryllium that is due to an accumulation of CD4{sup +} T cells at the site of disease activity. Diagnosis depends on the demonstration of pathologic changes (i.e., granuloma) and evidence that the granuloma was caused by a hypersensitivity to beryllium (i.e., positive lung proliferative response to beryllium). Using these criteria, the diagnosis of chronic beryllium disease can now be made before the onset of clinical symptoms. Whether, with early diagnosis, the natural course of this condition will be the same as when it was traditionally diagnosed is not known. Currently, corticosteroids are used to treat patients with significant symptoms or evidence of progressive disease. 21 refs.

  4. Chronic Beryllium Disease Prevention Program Report

    SciTech Connect (OSTI)

    Lee, S

    2012-03-29T23:59:59.000Z

    This document describes how Lawrence Livermore National Laboratory (LLNL) meets the requirements and management practices of federal regulation 10 CFR 850, 'Chronic Beryllium Disease Prevention Program (CBDPP).' This revision of the LLNL CBDPP incorporates clarification and editorial changes based on lessons learned from employee discussions, observations and reviews of Department of Energy (DOE) Complex and commercial industry beryllium (Be) safety programs. The information is used to strengthen beryllium safety practices at LLNL, particularly in the areas of: (1) Management of small parts and components; and (2) Communication of program status to employees. Future changes to LLNL beryllium activities and on-going operating experience will be incorporated into the program as described in Section S, 'Performance Feedback.'

  5. Pesticides and human chronic diseases: Evidences, mechanisms, and perspectives

    SciTech Connect (OSTI)

    Mostafalou, Sara; Abdollahi, Mohammad, E-mail: Mohammad.Abdollahi@UToronto.Ca

    2013-04-15T23:59:59.000Z

    Along with the wide use of pesticides in the world, the concerns over their health impacts are rapidly growing. There is a huge body of evidence on the relation between exposure to pesticides and elevated rate of chronic diseases such as different types of cancers, diabetes, neurodegenerative disorders like Parkinson, Alzheimer, and amyotrophic lateral sclerosis (ALS), birth defects, and reproductive disorders. There is also circumstantial evidence on the association of exposure to pesticides with some other chronic diseases like respiratory problems, particularly asthma and chronic obstructive pulmonary disease (COPD), cardiovascular disease such as atherosclerosis and coronary artery disease, chronic nephropathies, autoimmune diseases like systemic lupus erythematous and rheumatoid arthritis, chronic fatigue syndrome, and aging. The common feature of chronic disorders is a disturbance in cellular homeostasis, which can be induced via pesticides' primary action like perturbation of ion channels, enzymes, receptors, etc., or can as well be mediated via pathways other than the main mechanism. In this review, we present the highlighted evidence on the association of pesticide's exposure with the incidence of chronic diseases and introduce genetic damages, epigenetic modifications, endocrine disruption, mitochondrial dysfunction, oxidative stress, endoplasmic reticulum stress and unfolded protein response (UPR), impairment of ubiquitin proteasome system, and defective autophagy as the effective mechanisms of action. - Highlights: ? There is a link between exposure to pesticides and incidence of chronic diseases. ? Genotoxicity and proteotoxicity are two main involved mechanisms. ? Epigenetic knowledge may help diagnose the relationships. ? Efficient policies on safe use of pesticides should be set up.

  6. An approach for mining care trajectories for chronic diseases

    E-Print Network [OSTI]

    Boyer, Edmond

    An approach for mining care trajectories for chronic diseases Elias Egho1 ,Nicolas Jay1 , Chedy Ra of chronic patients. In this context, temporal data mining methods are promising tools, though lacking. We show the interest of our approach with the analysis of trajectories of care for colorectal cancer

  7. Collaborative Help in Chronic Disease Management: Supporting Individualized Problems

    E-Print Network [OSTI]

    Anderson, Richard

    Collaborative Help in Chronic Disease Management: Supporting Individualized Problems ABSTRACT for how diabetes patient support groups help one another find individualized strategies for managing diabetes community, and interviews, we found several help interactions that are critical in helping

  8. Status Report, Department of Energy's Chronic Beryllium Disease...

    Broader source: Energy.gov (indexed) [DOE]

    of 10 C.F.R. Part 850, Chronic Beryllium Disease Prevention Program, at the Department of Energy (DOE). The report is based on the results of evaluations of the effectiveness of...

  9. The Factors of Chronic Kidney Disease: Diabetes, Hypertension, Smoking, Drinking, Betelnut Chewing

    E-Print Network [OSTI]

    Chen, Chaur-Chin

    The Factors of Chronic Kidney Disease: Diabetes, Hypertension, Smoking, Drinking, Betelnut Chewing CKD 75 CKD Abstract The risk factors of Chronic Kidney Disease (CKD), including diabetes risk factors in a population-based cohort. Compared with single risk factors, diabetes (odds ratio 1

  10. Development of Biomarkers for Chronic Beryllium Disease in Mice

    SciTech Connect (OSTI)

    Gordon, Terry

    2013-01-25T23:59:59.000Z

    Beryllium is a strategic metal, indispensable for national defense programs in aerospace, telecommunications, electronics, and weaponry. Exposure to beryllium is an extensively documented occupational hazard that causes irreversible, debilitating granulomatous lung disease in as much as 3 - 5% of exposed workers. Mechanistic research on beryllium exposure-disease relationships has been severely limited by a general lack of a sufficient CBD animal model. We have now developed and tested an animal model which can be used for dissecting dose-response relationships and pathogenic mechanisms and for testing new diagnostic and treatment paradigms. We have created 3 strains of transgenic mice in which the human antigen-presenting moiety, HLA-DP, was inserted into the mouse genome. Each mouse strain contains HLA-DPB1 alleles that confer different magnitude of risk for chronic beryllium disease (CBD): HLA-DPB1*0401 (odds ratio = 0.2), HLA-DPB1*0201 (odds ratio = 15), HLA-DPB1*1701 (odds ratio = 240). Our preliminary work has demonstrated that the *1701 allele, as predicted by human studies, results in the greatest degree of sensitization in a mouse ear swelling test. We have also completed dose-response experiments examining beryllium-induced lung granulomas and identified susceptible and resistant inbred strains of mice (without the human transgenes) as well as quantitative trait loci that may contain gene(s) that modify the immune response to beryllium. In this grant application, we propose to use the transgenic and Â?normal inbred strains of mice to identify biomarkers for the progression of beryllium sensitization and CBD. To achieve this goal, we propose to compare the sensitivity and accuracy of the lymphocyte proliferation test (blood and bronchoalveolar lavage fluid) with the ELISPOT test in the three HLA-DP transgenic mice strains throughout a 6 month treatment with beryllium particles. Because of the availability of high-throughput proteomics, we will also identify changes in potential protein biomarkers in beryllium-treated mice. We will correlate these findings with the ability of the transgenic mice to develop a beryllium-specific adaptive immune response in blood and bronchoalveolar lavage (BAL) fluid. We will also determine whether beryllium-responsive CD4+ T cells in blood and BAL correlate with the onset of granuloma formation. Thus, we will provide the scientific community with biomarkers of sensitization and disease progression for CBD. These biomarkers will serve as critical tools for development of improved industrial hygiene and therapeutic interventions.

  11. Third Report of the California Hospital Outcomes Project (1997): Report on Heart Attack, 1991-1993 Volume 3

    E-Print Network [OSTI]

    Romano, Patrick S; Luft, Harold S; Rainwater, Julie A

    1997-01-01T23:59:59.000Z

    18 N O P Q Report on Heart Attack Hospital Detailed Results,18 N O P Q Report on Heart Attack Hospital Detailed Results,age, sex, type of heart attack, and chronic diseases were

  12. Naam: mw. prof. dr. ir. Y.T. van der Schouw Leeropdracht Chronic Disease Epidemiology

    E-Print Network [OSTI]

    Utrecht, Universiteit

    differ between men and women, and how menopause and estrogens might be involved in this risk difference against chronic diseases of aging, such as cardiovascular disease, breast cancer, osteoporosis diabetics have been submitted. The third and most important area is the role of menopause and estrogens

  13. Comparing Online Community Structure of Patients of Chronic Diseases

    E-Print Network [OSTI]

    Maddali, Hanuma Teja; Margolis, Peter

    2015-01-01T23:59:59.000Z

    In this paper we compare the social network structure of people talking about Crohn's disease, Cystic Fibrosis, and Type 1 diabetes on Facebook and Twitter. We find that the Crohn's community's contributors are most emotional on Facebook and Twitter and most negative on Twitter, while the T1D community's communication network structure is most cohesive.

  14. Prevalence of chronic obstructive pulmonary disease in rural women of

    E-Print Network [OSTI]

    Silver, Whendee

    for refining disease burden assessments attributable to household biomass combustion Priscilla Johnson1 January and May 2007. COPD assessments were done using a combination of clinical examination spend !2 hours/day in the kitchen involved in cooking. Use of solid fuel was associated with higher risk

  15. CS233917-AF National Center for Chronic Disease Prevention and Health Promotion

    E-Print Network [OSTI]

    CS233917-AF National Center for Chronic Disease Prevention and Health Promotion Division, Physical Activity, and Obesity Profile Obesity has important consequences on our nation's health by unhealthy options when it comes to diet and physical activity.We need public health approaches that make

  16. Chronic Kidney Disease and Hypertension: The Paradox of Treating Patients with Spironolactone

    E-Print Network [OSTI]

    Pillow, Jonathan

    Chronic Kidney Disease and Hypertension: The Paradox of Treating Patients with Spironolactone Amber the correlation between CKD and hypertension 2. Describe the role of aldosterone in the renin-angiotensin-aldosterone system (RAAS) and in resistant hypertension 3. Explain the mechanism of aldosterone antagonists 4

  17. Implementation Guide for use with 10 CFR Part 850, Chronic Beryllium Disease Prevention Program

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2001-01-04T23:59:59.000Z

    The Department of Energy (DOE) has established regulatory requirements for the Chronic Beryllium Disease Prevention Program (CBDPP) in Title 10 of the Code of Federal Regulations (CFR), Part 850 (10 CFR 850) [64 Federal Register (FR) 68854]. Cancels DOE G 440.1-7. Certified 9-23-10.

  18. Cancer Reporting Rule R384-100 R384. Health, Community Health Services, Chronic Disease.

    E-Print Network [OSTI]

    Tipple, Brett

    Cancer Reporting Rule R384-100 R384. Health, Community Health Services, Chronic Disease. R384-100. Cancer Reporting Rule R384-100-1. Purpose Statement (1) The Cancer Reporting Rule is adopted under authority of sections 26-1-30 and 26-5-3. (2) Cancers Constitute a leading cause of morbidity and mortality

  19. Impact of Palivizumab on RSV Hospitalizations for Children with Hemodynamically Significant Congenital Heart Disease

    E-Print Network [OSTI]

    Chang, Ruey-Kang R.; Chen, Alex Y.

    2010-01-01T23:59:59.000Z

    in infants with congenital heart disease. Pediatrics 114:children with congenital heart disease. The Cardiac StudySigni?cant Congenital Heart Disease Ruey-Kang R. Chang •

  20. Chronic graft-versus-host disease in the rat radiation chimera. III. Immunology and immunopathology in rapidly induced models

    SciTech Connect (OSTI)

    Beschorner, W.E.; Tutschka, P.J.; Santos, G.W.

    1983-03-01T23:59:59.000Z

    Although chronic graft-versus-host disease (GVHD) frequently develops in the long-term rat radiation chimera, we present three additional models in which a histologically similar disease is rapidly induced. These include adoptive transfer of spleen and bone marrow from rats with spontaneous chronic GVHD into lethally irradiated rats of the primary host strain; sublethal irradiation of stable chimeras followed by a booster transplant; and transfer of spleen cells of chimeras recovering from acute GVHD into second-party (primary recipient strain) or third-party hosts. Some immunopathologic and immune abnormalities associated with spontaneous chronic GVHD were not observed in one or more of the induced models. Thus, IgM deposition in the skin, antinuclear antibodies, and vasculitis appear to be paraphenomena. On the other hand, lymphoid hypocellularity of the thymic medulla, immaturity of splenic follicles, and nonspecific suppressor cells were consistently present in the long term chimeras, and in all models. These abnormalities therefore may be pathogenetically important, or closely related to the development of chronic GVHD.

  1. LEVEL OF HIGH-SENSITIVITY C-REACTIVE PROTEIN IN SAUDI PATIENTS WITH CHRONIC STABLE CORONARY ARTERY DISEASE

    E-Print Network [OSTI]

    J Ayub; Med Coll Abbottabad; Syed Shahid Habib

    Background: Inflammatory biomarker high-sensitivity C-reactive protein (hsCRP) is an independent predictor of future cardiovascular events and it predicts risk of incident hypertension and diabetes. The aim of this study was to determine the serum levels of the circulating acute-phase reactant high-sensitivity C-reactive protein (hsCRP) in Saudi patients with chronic stable Coronary Artery Disease (CAD). Methods: This cross

  2. CORONARY HEART DISEASE RISK STRATIFICATION IN FULL-TIME MIAMI VALLEY HOSPITAL EMPLOYEES.

    E-Print Network [OSTI]

    Streng, Vicki K.

    2006-01-01T23:59:59.000Z

    ??Streng, Vicki. M.S. College of Science and Mathematics, Department of Biological Sciences, Wright State University, 2006. Coronary Heart Disease Risk Stratification in Full-time Miami Valley… (more)

  3. Efficacy of DVD Technology in Chronic Obstructive Pulmonary Disease Self- Management Education of Rural Patients

    E-Print Network [OSTI]

    Stellefson, Michael L.

    2010-01-14T23:59:59.000Z

    (chronic bronchitis) and parenchyma destruction (emphysema), the relative contributions of which differ from person to person (Buist et al., 2007). This causes an obstruction of air leaving the lungs, and consequently, prolonged episodes of coughing..., 2001). Exacerbations are defined as events in COPD characterized by change in patients? baseline dyspnea, cough, chest tightness and/or sputum that is beyond normal day-to-day variations and acute in onset (Burge & Wedzicha, 2003). Lung infections...

  4. E-Print Network 3.0 - addressing chronic disease Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Human Development Faculty Research Themes Summary: Cardiovascular and Circulatory Disease W. Larry Kenney Professor Kinesiology Email Address: W7K@PSU.EDU Research... ; the...

  5. Hospitality Management Hospitality Management

    E-Print Network [OSTI]

    McConnell, Terry

    of the global hospitality industry. Academic Offerings HOSPITALITY AND FOOD SERVICE MANAGEMENT MINOR HOSPITALITY AND FOOD SERVICE MANAGEMENT MINOR Students pursuing programs in other areas of study may choose a minor Lodging Management 3 HPM 309 Sports Arena Management 3 HPM 312* Cost Control in Food Services (Prereq

  6. A Perspective on the Maillard Reaction and the Analysis of Protein Glycation by Mass Spectrometry: Probing the Pathogenesis of Chronic Disease

    SciTech Connect (OSTI)

    Zhang, Qibin; Ames, Jennifer M.; Smith, Richard D.; Baynes, John; Metz, Thomas O.

    2008-12-18T23:59:59.000Z

    The Maillard reaction, starting from the glycation of protein and progressing to the formation of advanced glycation end-products (AGEs), is implicated in the development of complications of diabetes mellitus, as well as in the pathogenesis of cardiovascular, renal, and neurodegenerative diseases. In this perspective review, we provide on overview on the relevance of the Maillard reaction in the pathogenesis of chronic disease and discuss traditional approaches and recent developments in the analysis of glycated proteins by mass spectrometry. We propose that proteomics approaches, particularly bottom-up proteomics, will play a significant role in analyses of clinical samples leading to the identification of new markers of disease development and progression.

  7. Chronic graft-versus-host disease in the rat radiation chimera: I. clinical features, hematology, histology, and immunopathology in long-term chimeras

    SciTech Connect (OSTI)

    Beschorner, W.E.; Tutschka, P.J.; Santos, G.W.

    1982-04-01T23:59:59.000Z

    The clinical features, pathology, and immunopathology of chronic graft-versus-host disease (GVHD) developing in the long-term rat radiation chimera are described. At 6 to 12 months post-transplant, the previously stable ACI/LEW chimeras developed patchy to diffuse severe hair loss and thickened skin folds, and had microscopic features resembling scleroderma, Sjogren's syndrome, and chronic hepatitis. Skin histology showed dermal inflammation and acanthosis with atrophy of the appendages, with progression to dermal sclerosis. The liver revealed chronic hepatitis with bile duct injury and proliferation and periportal piecemeal necrosis. The tongue had considerable submucosal inflammation, muscular necrosis, and atrophy and arteritis. The serous salivary glands, lacrimal glands, and bronchi had lymphocytic inflammation and injury to duct, acinar, and mucosal columnar epithelium. The thymus had lymphocyte depletion of the medulla with prominent epithelium. The spleen and lymph nodes had poorly developed germinal centers but increased numbers of plasma cells. IgM was observed along the basement membrane and around the basal cells of the skin and tongue and along the basement membrane of the bile ducts. IgM was present also in the arteries of the tongue. Immunoglobulins eluted from the skin, cross-reacted with the bile duct epithelium and usually with both ACI and Lewis skin. Increased titers of speckled antinuclear antibodies were present in the serum of rats with chronic (GVHD). Chronic GVHD in the long-term rat radiation chimera is very similar to human chronic GVHD and is a potentially excellent model for autoimmune disorders including scleroderma, Sjorgren's syndrome, and chronic hepatitis.

  8. Hospital Renovations

    Broader source: Energy.gov [DOE]

    Hospitals have a range of energy needs that vary from a typical building, and a number of renewable energy options may make more sense for a hospital, including process and biomass heating, photovoltaics (PV), and sustainability.

  9. age chronic non-communicable: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    disease. Early symptoms of COPD include excessive sputum production and chronic cough. The primary (more) Toljamo, Tuula 2012-01-01 9 Parkinson disease (PD) is a chronic,...

  10. Sex-specific differences in hyperoxic lung injury in mice: Implications for acute and chronic lung disease in humans

    SciTech Connect (OSTI)

    Lingappan, Krithika, E-mail: lingappa@bcm.edu [Department of Pediatrics, Section of Neonatology, Texas Children's Hospital, Baylor College of Medicine, 1102 Bates Avenue, MC: FC530.01, Houston, TX 77030 (United States); Jiang, Weiwu; Wang, Lihua; Couroucli, Xanthi I. [Department of Pediatrics, Section of Neonatology, Texas Children's Hospital, Baylor College of Medicine, 1102 Bates Avenue, MC: FC530.01, Houston, TX 77030 (United States); Barrios, Roberto [Department of Pathology and Genomic Medicine, The Methodist Hospital Physician Organization, 6565 Fannin Street, Suite M227, Houston, TX 77030 (United States); Moorthy, Bhagavatula [Department of Pediatrics, Section of Neonatology, Texas Children's Hospital, Baylor College of Medicine, 1102 Bates Avenue, MC: FC530.01, Houston, TX 77030 (United States)

    2013-10-15T23:59:59.000Z

    Sex-specific differences in pulmonary morbidity in humans are well documented. Hyperoxia contributes to lung injury in experimental animals and humans. The mechanisms responsible for sex differences in the susceptibility towards hyperoxic lung injury remain largely unknown. In this investigation, we tested the hypothesis that mice will display sex-specific differences in hyperoxic lung injury. Eight week-old male and female mice (C57BL/6J) were exposed to 72 h of hyperoxia (FiO{sub 2} > 0.95). After exposure to hyperoxia, lung injury, levels of 8-iso-prostaglandin F{sub 2} alpha (8-iso-PGF 2?) (LC–MS/MS), apoptosis (TUNEL) and inflammatory markers (suspension bead array) were determined. Cytochrome P450 (CYP)1A expression in the lung was assessed using immunohistochemistry and western blotting. After exposure to hyperoxia, males showed greater lung injury, neutrophil infiltration and apoptosis, compared to air-breathing controls than females. Pulmonary 8-iso-PGF 2? levels were higher in males than females after hyperoxia exposure. Sexually dimorphic increases in levels of IL-6 (F > M) and VEGF (M > F) in the lungs were also observed. CYP1A1 expression in the lung was higher in female mice compared to males under hyperoxic conditions. Overall, our results support the hypothesis that male mice are more susceptible than females to hyperoxic lung injury and that differences in inflammatory and oxidative stress markers contribute to these sex-specific dimorphic effects. In conclusion, this paper describes the establishment of an animal model that shows sex differences in hyperoxic lung injury in a temporal manner and thus has important implications for lung diseases mediated by hyperoxia in humans. - Highlights: • Male mice were more susceptible to hyperoxic lung injury than females. • Sex differences in inflammatory markers were observed. • CYP1A expression was higher in females after hyperoxia exposure.

  11. Reconfiguring Care for Chronic Disease with Home Monitoring: A Pilot Study Report on Telemetry-Supported Care for COPD Patients in the Lothian Region 

    E-Print Network [OSTI]

    Ure, Jenny; Kydd, Gillian; Tarling, Alex; McKinstry, Brian; Hanley, Janet; Pagliari, Claudia; Pinnock, Hilary; Sheikh, Aziz; MacNee, William; McCall Smith, Emily; Corscadden, Paddy

    2009-01-01T23:59:59.000Z

    A qualitative report of users' experiences of home telemonitoring in COPD (Chronic Obstructive Lung Disorder) in Lothian Region. This research, with patients, carers, nurses, physiotherapists and GPs provided an early ...

  12. E-Print Network 3.0 - adefovir resistant chronic Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    heart disease, etc.) --until relatively recently, communicable... --largely due to poor sanitation, insecure water supplies, malnutrition 12;2 --chronic diseases such as...

  13. Sex-dependent effects of chronic restraint stress during early Theiler's virus infection on the subsequent demyelinating disease in CBA mice

    E-Print Network [OSTI]

    Meagher, Mary

    ,b , Ralph Storts c , Thomas H. Welsh b,d , C. Jane R. Welsh b,c , Mary W. Meagher a,* a Department 350,000 people in the United States alone (Anderson et al., 1992). Though the etiology of MS remains of the disease (Ackerman et al., 2003; Anderson et al., 1992; Mohr and Cox, 2001; Mohr et al., 2004; Noseworthy

  14. IAQ in Hospitals - Better Health through Indoor Air Quality Awareness

    E-Print Network [OSTI]

    Al-Rajhi, S.; Ramaswamy, M.; Al-Jahwari, F.

    2010-01-01T23:59:59.000Z

    .S, 2004). Nordstrom and his team from Sweden investigated IAQ in hospitals in relation to building dampness and type of construction. They analyzed four hospital buildings of different age and design and concluded that building dampness in the floor...? Department of Occupational and Environmental Medicine, Uppsala University hospital, Sweden.1998 Proc CIB World Building Congress ,Gaevle,Sweden. ? O'Neal C. Infection control; Keeping diseases at bay a full-time effort for healthcare professionals...

  15. Accidental Hospital Deaths

    E-Print Network [OSTI]

    Bhat, Prashant

    2011-01-01T23:59:59.000Z

    Staphylococcus Aureus (MRSA) Bloodstream Infections. Scienceof Antibiotic-Resistant MRSA Bacteria. Consumersunion.org.Staphylococcus Aureus (MRSA), the leading cause of hospital

  16. Third Report of the California Hospital Outcomes Project (1997): Report on Heart Attack, 1991-1993 Volume 1

    E-Print Network [OSTI]

    Romano, Patrick S; Luft, Harold S; Rainwater, Julie A

    1997-01-01T23:59:59.000Z

    age, sex, type of heart attack, and chronic diseases wereand location of the heart attack, and the specific chronicP S , Luft HS. Report on Heart Attack 1991-1993, Volume 1:

  17. Rhodes Hall Ross Heart Hospital

    E-Print Network [OSTI]

    Howat, Ian M.

    Emergency 315 315 26 Rhodes Hall Ross Heart Hospital James Cancer Hospital Martha Morehouse.m. James Cancer Hospital 7:10 a.m. Rhodes Hall 7:13 a.m. Ross Heart Hospital 7:15 a.m. Martha Morehouse

  18. Chronic Beryllium Disease Prevention Program What's New

    Broader source: Energy.gov [DOE]

    For additional information Contact: David Weitzman, Office of Worker Safety and Health Policy at (301) 903-5401 or: David.Weitzman@hq.doe.gov.

  19. Cadmium, diabetes and chronic kidney disease

    SciTech Connect (OSTI)

    Edwards, Joshua R. [Department of Pharmacology, Midwestern University, Downers Grove, IL 60515 (United States)], E-mail: jedwar@midwestern.edu; Prozialeck, Walter C. [Department of Pharmacology, Midwestern University, Downers Grove, IL 60515 (United States)

    2009-08-01T23:59:59.000Z

    Recent epidemiological studies suggest a positive association between exposure to the environmental pollutant cadmium (Cd) and the incidence and severity of diabetes. In this review, we examine the literature suggesting a relationship between Cd exposure, elevated blood glucose levels, and the development of diabetes. In addition we review human and animal studies indicating that Cd potentiates or exacerbates diabetic nephropathy. We also review the various possible cellular mechanisms by which Cd may alter blood glucose levels. In addition, we present some novel findings from our own laboratories showing that Cd elevates fasting blood glucose levels in an animal model of subchronic Cd exposure before overt signs of renal dysfunction are evident. These studies also show that Cd reduces insulin levels and has direct cytotoxic effects on the pancreas. Together, these findings indicate that Cd may be a factor in the development of some types of diabetes and they raise the possibility that Cd and diabetes-related hyperglycemia may act synergistically to damage the kidney.

  20. E-Print Network 3.0 - acid peptic disease Sample Search Results

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ), asthma, chronic bronchitis, emphysema, epilepsy, gastricpeptic ulcer dis- ease, gout, ocular... and systemic hypertension, peripheral vascular disease, and stroke (ischemic...

  1. E-Print Network 3.0 - allergic ocular diseases Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ), asthma, chronic bronchitis, emphysema, epilepsy, gastricpeptic ulcer dis- ease, gout, ocular... and systemic hypertension, peripheral vascular disease, and stroke (ischemic...

  2. HumanoidHospital Sustainable

    E-Print Network [OSTI]

    Beex, A. A. "Louis"

    HHO HumanoidHospital Nanoscale Science Nano-Bio Interface Sustainable Energy Renewable Materials Areas Vision IcHHo will address the problem of accidental medical errors by developing an intelligent real-life medical scenarios. Mission IcHHO will develop interactive Humanoid Patients (male, female

  3. HOSPITAL ENERGY AUDITS: A BIBLIOGRAPHY

    E-Print Network [OSTI]

    Pollack, R. I.

    2011-01-01T23:59:59.000Z

    J.W. "Professional Energy Audit Points Way to $100,000Hosp-79-3 NIA HOSPITAL ENERGY AUDITS: A BIBLIOGRAPHY R. I.information. HOSPITAL ENERGY AUDIT REPORTS Anco Engineers

  4. TOURISM AND HOSPITALITY MANAGEMENT (TOUR)

    E-Print Network [OSTI]

    Calgary, University of

    TOURISM AND HOSPITALITY MANAGEMENT (TOUR) Bachelor of Commerce Degree The tourism industry & conferences, adventure tourism, travel trade, and tourism services. The Tourism and Hospitality concentration integrates general management concepts with the professional knowledge that is required by the tourism

  5. Beryllium disease

    SciTech Connect (OSTI)

    Not Available

    1991-12-20T23:59:59.000Z

    After two workers at the nuclear weapons plant at Oak Ridge National Laboratory in Tennessee were diagnosed earlier this year with chronic beryllium disease (CBD), a rare and sometimes fatal scarring of the lungs, the Department of Energy ordered up a 4-year probe. Now, part of that probe has begun - tests conducted by the Oak Ridge Associated Universities' Center for Epidemiological Research measuring beryllium sensitivity in 3,000 people who've been exposed to the metal's dust since Manhattan Project managers opened the Y-12 plant at Oak Ridge in 1943. Currently, 119 Y-12 employees process beryllium, which has a number of industrial uses, including rocket heat shields and nuclear weapon and electrical components. The disease often takes 20 to 25 years to develop, and the stricken employees haven't worked with beryllium for years. There is no cure for CBD, estimated to strike 2% of people exposed to the metal. Anti-inflammatory steroids alleviate such symptoms as a dry cough, weight loss, and fatigue. Like other lung-fibrosis diseases that are linked to lung cancer, some people suspect CBD might cause some lung cancer. While difficult to diagnose, about 900 cases of CBD have been reported since a Beryllium Case Registry was established in 1952. The Department of Energy (DOE) estimates that about 10,000 DOE employees and 800,000 people in private industry have worked with beryllium.

  6. Cough REVIEW Chronic cough hypersensitivity syndrome

    E-Print Network [OSTI]

    Alyn H Morice

    Chronic cough has been suggested to be due to three conditions, asthma, post nasal drip, and reflux disease. A different paradigm has evolved in which cough is viewed as the primary condition characterised by afferent neuronal hypersensitivity and different aspects of this syndrome are manifest in the different phenotypes of cough. There are several advantages to viewing cough hypersensitivity as the unifying diagnosis; Communication with patients is aided, aetiology is not restricted and therapeutic avenues opened. Cough Hypersensitivity Syndrome is a more applicable label to embrace the clinical manifestations of this disabling disease.

  7. Radiation Protection Guidance Hospital Staff

    E-Print Network [OSTI]

    Kay, Mark A.

    Page 1 Radiation Protection Guidance For Hospital Staff Prepared for Stanford The privilege to use ionizing radiation at Stanford University, Stanford Hospital and Clinics, Lucile Packard with radioactive materials or radiation devices are responsible for knowing and adhering to applicable requirements

  8. Hospital valuation in emerging countries

    E-Print Network [OSTI]

    Segawa, Tsuyoshi, M.B.A. Massachusetts Institute of Technology

    2013-01-01T23:59:59.000Z

    Private health players in emerging countries have increased their presence and contributed to global health issues, but have been undervalued in financing. A variety of health players have evolved and hospitals have played ...

  9. E-Print Network 3.0 - acute gastrointestinal disease Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    erythematosus (SLE) 3. Scleroderma (Systemic sclerosis) 4. Crystal induced disease (Gout... : acute and chronic 3. Connective tissue 4. Joints (focus on synovium) 5....

  10. E-Print Network 3.0 - acute bacterial diseases Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    erythematosus (SLE) 3. Scleroderma (Systemic sclerosis) 4. Crystal induced disease (Gout... : acute and chronic 3. Connective tissue 4. Joints (focus on synovium) 5....

  11. Third Report of the California Hospital Outcomes Project (1997): Report on Heart Attack, 1991-1993 Volume 2

    E-Print Network [OSTI]

    Romano, Patrick S; Luft, Harold S; Rainwater, Julie A

    1997-01-01T23:59:59.000Z

    age, sex, type of heart attack, and chronic diseases wereJA, Zach AP. Report on Heart Attack 1991-1993, Volume 2:California, Santa Barbara Heart Attack Clinical Panel Melvin

  12. Design of a numerical model for simulation of blood microcirculation and study of sickle cell disease

    E-Print Network [OSTI]

    Le Floch-Yin, François T. (François Thomas)

    2010-01-01T23:59:59.000Z

    Sickle cell disease is nowadays one of the most challenging blood diseases, where patients suffer from both chronic and acute episodes of painful medical conditions. In particular, unpredictable crises due to blood vessel ...

  13. Hospital A Hospital B Hospital C Practice Variation in Emergency Department Management of Children

    E-Print Network [OSTI]

    in Emergency Department Management of Children with Sickle Cell Disease who Present with Fever Katherine for all patients with sickle cell disease (SCD) who present with fever. · Complete blood count (CBC sickle cell centers between 1/1/08 and 12/31/12. · Chart reviews were performed on all visits of children

  14. Hospital Analytics | GE Global Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsruc DocumentationP-SeriesFlickr FlickrGuidedCH2MLLC HistoryVeterans | Updates and StatusHospital

  15. EAT SMART -Chronic Disease Program MONTH TOPIC PROGRAM DETAILS

    E-Print Network [OSTI]

    SMART for Bone Health Discuss the risk factors associated with osteoporosis and the steps necessary on the risk factors for osteoporosis, and how to promote bone health by consuming foods rich in calcium

  16. Chronic Beryllium Disease Prevention Program (10 CFR 850) | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:YearRound-Up fromDepartmentTieCelebrate Earth DayFuels ChemicalChris Galm About

  17. Title 10 CFR Part 850, Chronic Beryllium Disease Prevention Program

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear SecurityTensile Strain Switched Ferromagnetism in Layered NbS2 andThe1A:decisional. 1 B O N NUnlocking Office of

  18. college of hospitality, retail and sport management college of hospitality, retail and sport management

    E-Print Network [OSTI]

    Almor, Amit

    educate new workers and drive innovations to build on the most sustainable and promising areas of economiccollege of hospitality, retail and sport management #12;college of hospitality, retail and sport management "We believe in our vision: The College of Hospitality, Retail and Sport Management prepares

  19. Using family history information to promote healthy lifestyles and prevent diseases;a discussion of the evidence

    E-Print Network [OSTI]

    Claassen, Liesbeth; Henneman, Lidewij; Janssens, A Cecile J W; Wijdenes-Pijl, Miranda; Qureshi, Nadeem; Walter, Fiona M; Yoon, Paula W; Timmermans, Danielle R M

    2010-05-13T23:59:59.000Z

    Abstract Background A family history, reflecting genetic susceptibility as well as shared environmental and behavioral factors, is an important risk factor for common chronic multifactorial diseases such as cardiovascular diseases, type 2 diabetes...

  20. Biomedical Monitoring of Non-Hospitalized Subjects

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Biomedical Monitoring of Non-Hospitalized Subjects using Disruption-Tolerant Wireless Sensors for the collection of biomedical data produced by sensors carried by mobile non-hospitalized subjects. In this paper we investigate the possibility of using these many hotspots as gateways for biomedical data

  1. Modesto Memorial Hospital Space Heating Low Temperature Geothermal...

    Open Energy Info (EERE)

    Memorial Hospital Space Heating Low Temperature Geothermal Facility Jump to: navigation, search Name Modesto Memorial Hospital Space Heating Low Temperature Geothermal Facility...

  2. Warm Springs State Hospital Space Heating Low Temperature Geothermal...

    Open Energy Info (EERE)

    State Hospital Space Heating Low Temperature Geothermal Facility Jump to: navigation, search Name Warm Springs State Hospital Space Heating Low Temperature Geothermal Facility...

  3. Combined Heat and Power (CHP) Resource Guide for Hospital Applications...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Combined Heat and Power (CHP) Resource Guide for Hospital Applications, 2007 Combined Heat and Power (CHP) Resource Guide for Hospital Applications, 2007 The objective of this 2007...

  4. Fort Boise Veteran's Hospital District Heating Low Temperature...

    Open Energy Info (EERE)

    Veteran's Hospital District Heating Low Temperature Geothermal Facility Jump to: navigation, search Name Fort Boise Veteran's Hospital District Heating Low Temperature Geothermal...

  5. Jackson Park Hospital Green Building Medical Center

    SciTech Connect (OSTI)

    William Dorsey; Nelson Vasquez

    2010-03-01T23:59:59.000Z

    Jackson Park Hospital completed the construction of a new Medical Office Building on its campus this spring. The new building construction has adopted the City of Chicago�s recent focus on protecting the environment, and conserving energy and resources, with the introduction of green building codes. Located in a poor, inner city neighborhood on the South side of Chicago, Jackson Park Hospital has chosen green building strategies to help make the area a better place to live and work.

  6. Percutaneous Endovascular Treatment of Chronic Iliac Artery Occlusion

    SciTech Connect (OSTI)

    Carnevale, F. C. [Institute of Radiology, University of Sao Paulo, Department of Interventional Radiology (Brazil)], E-mail: fcarnevale@uol.com.br; De Blas, Mariano; Merino, Santiago; Egana, Jose M. [Hospital De Guipuzcoa, Department of Radiology (Spain); Caldas, Jose G.M.P. [Institute of Radiology, University of Sao Paulo, Department of Interventional Radiology (Brazil)

    2004-09-15T23:59:59.000Z

    Purpose: To evaluate the clinical and radiological long-term results of recanalization of chronic occluded iliac arteries with balloon angioplasty and stent placement.Methods: Sixty-nine occluded iliac arteries (mean length 8.1 cm; range 4-16 cm) in 67 patients were treated by percutaneous transluminal angioplasty and stent placement. Evaluations included clinical assesment according to Fontaine stages, Doppler examinations with ankle-brachial index (ABI) and bilateral lower extremity arteriograms. Wallstent and Cragg vascular stents were inserted for iliac artery recanalization under local anesthesia. Follow-up lasted 1-83 months (mean 29.5 months).Results: Technical success rate was 97.1% (67 of 69). The mean ABI increased from 0.46 to 0.85 within 30 days after treatment and was 0.83 at the most recent follow-up. Mean hospitalization time was 2 days and major complications included arterial thrombosis (3%), arterial rupture (3%) and distal embolization (1%). During follow-up 6% stenosis and 9% thrombosis of the stents were observed. Clinical improvement occurred in 92% of patients. Primary and secondary patency rates were 75% and 95%, respectively.Conclusion: The long-term patency rates and clinical benefits suggest that percutaneous endovascular revascularization with metallic stents is a safe and effective treatment for patients with chronic iliac artery occlusion.

  7. Chronic Copper Poisoning in Sheep.

    E-Print Network [OSTI]

    Boughton, I. B. (Ivan Bertrand); Hardy, W. T. (William Tyree)

    1934-01-01T23:59:59.000Z

    IN SHEEP LIBRARY A~ricufl~ml& Hechanicnl Colleqe ol Texas , Texas. AGRICULTURAL AND MECHANICAL COLLEGE OF TEXAS T. 0. WALTON, President 3erk tant sl Asst. --------. - ---- - '31 Administration : Veterinary Science : A. B. Conner, M. S.. Director... of copper sulphate caused chronic copper poisoning among flocks of range sheep on several West Texas ranches during the past year. The salt licks were placed before the sheep as a means of preventing or controlling stomach worm infestation despite a...

  8. 284 SDSU General Catalog 2012-2013 Hospitality and Tourism

    E-Print Network [OSTI]

    Gallo, Linda C.

    284 SDSU General Catalog 2012-2013 Hospitality and Tourism Management In the College of Hospitality and Tourism Management Master of Science degree in hospitality and tourism management. Major in hospitality and tourism management with the B.S. degree in applied arts and sciences. Emphasis in global

  9. Results of a hospital waste survey in private hospitals in Fars province, Iran

    SciTech Connect (OSTI)

    Askarian, Mehrdad; Vakili, Mahmood; Kabir, Gholamhosein

    2004-07-01T23:59:59.000Z

    Hospital waste is considered dangerous because it may possess pathogenic agents and can cause undesirable effects on human health and the environment. In Iran, neither rules have been compiled nor does exact information exist regarding hospital waste management. The survey presented in this article was carried out in all 15 private hospitals of Fars province (Iran) from the total numbers of 50 governmental and private hospitals located in this province, in order to determine the amount of different kinds of waste produced and the present situation of waste management. The results indicated that the waste generation rate is 4.45 kg/bed/day, which includes 1830 kg (71.44%) of domestic waste, 712 kg (27.8%) of infectious waste, and 19.6 kg (0.76%) of sharps. Segregation of the different types of waste is not carried out perfectly. Two (13.3%) of the hospitals use containers without lids for on-site transport of wastes. Nine (60%) of the hospitals are equipped with an incinerator and six of them (40%) have operational problems with the incinerators. In all hospitals municipal workers transport waste outside the hospital premises daily or at the most on alternative days. In the hospitals under study, there aren't any training courses about hospital waste management and the hazards associated with them. The training courses that are provided are either ineffective or unsuitable. Performing extensive studies all over the country, compiling and enacting rules, establishing standards and providing effective personnel training are the main challenges for the concerned authorities and specialists in this field.

  10. Respiratory disease in Utah coal miners

    SciTech Connect (OSTI)

    Rom, W.N.; Kanner, R.E.; Renzetti, A.D. Jr.; Shigeoka, J.W.; Barkman, H.W.; Nichols, M.; Turner, W.A.; Coleman, M.; Wright, W.E.

    1981-04-01T23:59:59.000Z

    Two hundred forty-two Utah underground coal miners volunteered to participate in a respiratory disease study. They were an older group (mean, 56 years of age) and had spent a mean of 29 years in the coal-mining industry. The prevalence of chronic bronchitis was 57%, and that of coal worker's pneumoconiosis, 25%; only one worker had progressive massive fibrosis. Significant impairment of pulmonary function was found among those with a history of cigarette smoking. Chronic bronchitis or coal worker's penumoconiosis among nonsmokers did not impair pulmonary function. There was a significant association among the nonsmokers between increasing exposure to coal dust and coal worker's pneumoconiosis, but not for changes in pulmonary function. Coal mine dust had a significant influence in causing the symptom complex of chronic cough and sputum production, and coal worker's pneumoconiosis.

  11. Respiratory disease in Utah coal miners

    SciTech Connect (OSTI)

    Rom, W.N.; Kanner, R.E.; Renzetti, A.D. Jr.; Shigeoka, J.W.; Barkman, H.W.; Nichols, M.; Turner, W.A.; Coleman, M.; Wright, W.E.

    1981-04-01T23:59:59.000Z

    Two hundred forty-two Utah underground coal miners volunteered to participate in a respiratory disease study. They were an older group (mean, 56 years of age) and had spent a mean of 29 years in the coal-mining industry. The prevalence of chronic bronchitis was 57%, and that of coal worker's pneumoconiosis, 25%; only one worker had progressive massive fibrosis. Significant impairment of pulmonary function was found among those with a history of cigarette smoking. Chronic bronchitis or coal worker's pneumoconiosis among nonsmokers did not impair pulmonary function. There was a significant association among the nonsmokers between increasing exposure to coal dust and coal worker's pneumoconiosis, but not for changes in pulmonary function. Coal mine dust had a significant influence in causing the symptom complex of chronic cough and sputum production, and coal worker's pneumoconiosis.

  12. Pulmonary arterial hypertension and cor pulmonale associated with chronic domestic woodsmoke inhalation

    SciTech Connect (OSTI)

    Sandoval, J.; Salas, J.; Martinez-Guerra, M.L.; Gomez, A.; Martinez, C.; Portales, A.; Palomar, A.; Villegas, M.; Barrios, R. (Instituto Nacional de Cardiologia, Ignacio Chavez, Mexico City (Mexico))

    1993-01-01T23:59:59.000Z

    We describe the clinical, radiologic, functional, and pulmonary hemodynamic characteristics of a group of 30 nonsmoking patients with a lung disease that may be related to intense, long-standing indoor wood-smoke exposure. The endoscopic and some of the pathologic findings are also presented. Intense and prolonged wood-smoke inhalation may produce a chronic pulmonary disease that is similar in many aspects to other forms of inorganic dust-exposure interstitial lung disease. It affects mostly country women in their 60s, and severe dyspnea and cough are the outstanding complaints. The chest roentgenograms show a diffuse, bilateral, reticulonodular pattern, combined with normalized or hyperinflated lungs, as well as indirect signs of pulmonary arterial hypertension (PAH). On the pulmonary function test the patients show a mixed restrictive-obstructive pattern with severe hypoxemia and variable degrees of hypercapnia. Endoscopic findings are those of acute and chronic bronchitis and intense anthracotic staining of the airways appears to be quite characteristic. Fibrous and inflammatory focal thickening of the alveolar septa as well as diffuse parenchymal anthracotic deposits are the most prominent pathologic findings, although inflammatory changes of the bronchial epithelium are also present. The patients had severe PAH in which, as in other chronic lung diseases, chronic alveolar hypoxia may play the main pathogenetic role. However, PAH in wood-smoke inhalation-associated lung disease (WSIALD) appears to be more severe than in other forms of interstitial lung disease and tobacco-related COPD. The patients we studied are a selected group and they may represent one end of the spectrum of the WSIALD.

  13. FEATURE ARTICLE 2 Kunde Hospital: Nepal

    E-Print Network [OSTI]

    Rambaut, Andrew

    FEATURE ARTICLE 2 Kunde Hospital: Nepal WORK IN PROGRESS 4 Public Health in Ceylon Medical research of the Mt Everest area in Nepal who have played such an important role in Himalayan mountaineering century the region became incorporated into the Gorkha kingdom that now forms the modern nation of Nepal

  14. FOOD SUSTAINABILITY REPORT QUEEN'S HOSPITALITY SERVICES

    E-Print Network [OSTI]

    Ellis, Randy

    FOOD SUSTAINABILITY REPORT QUEEN'S HOSPITALITY SERVICES May 2008 #12;In recent years, a sustainability movement has taken root at Queen's. The impacts of the movement can be seen across campus sustainability position within the their student government ­The AMS, The Engineer Society open the Tea Room

  15. active chronic hepatitis: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Summary: ??abstractChronic hepatitis C virus infection (HCV) affects 180 million people worldwide. Chronic HCV can cause hepatic decompensation, hepatocellular carcinoma...

  16. advanced chronic hepatitis: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Summary: ??abstractChronic hepatitis C virus infection (HCV) affects 180 million people worldwide. Chronic HCV can cause hepatic decompensation, hepatocellular carcinoma...

  17. Hospital Readmission in General Medicine Patients: A Prediction Model

    E-Print Network [OSTI]

    2010-01-01T23:59:59.000Z

    J Med. 1985;313: JGIM Hasan et al. : Hospital ReadmissionA Prediction Model Omar Hasan, MBBS, MPH 1,2 , David O.online December 15, 2009 Hasan et al. : Hospital Readmission

  18. Occupational exposures and chronic respiratory symptoms. A population-based study

    SciTech Connect (OSTI)

    Korn, R.J.; Dockery, D.W.; Speizer, F.E.; Ware, J.H.; Ferris, B.G. Jr.

    1987-08-01T23:59:59.000Z

    Data from a random sample of 8515 white adults residing in 6 cities in the eastern and midwestern United States were used to examine the relationships between occupational exposures to dust or to gases and fumes and chronic respiratory symptoms; 31% of the population had a history of occupational dust exposure and 30% reported exposure to gas or fumes. After adjusting for smoking habits, age, gender, and city of residence, subjects with either occupational exposure had significantly elevated prevalences of chronic cough, chronic phlegm, persistent wheeze, and breathlessness. The adjusted relative odds of chronic respiratory symptoms for subjects exposed to dust ranged from 1.32 to 1.60. Subjects with gas or fume exposure had relative odds of symptoms between 1.27 and 1.43 when compared with unexposed subjects. Occupational dust exposure was associated with a higher prevalence of chronic obstructive pulmonary disease as defined by an FEV1/FVC ratio of less than 0.6, when comparing exposed and unexposed participants (OR = 1.53, 95% Cl = 1.17-2.08). Gas or fume exposure was associated with a small, but not significant, increase in COPD prevalence. Significant trends were noted for wheeze and phlegm with increasing duration of dust exposure. Although 36% of exposed subjects reported exposure to both dust and fumes, there was no evidence of a multiplicative interaction between the effects of the individual exposures. Smoking was a significant independent predictor of symptoms, but did not appear to modify the effect of dust or fumes on symptom reporting. These data, obtained in random samples of general populations, demonstrate that chronic respiratory symptoms and disease can be independently associated with occupational exposures.

  19. Occupational exposures and chronic respiratory symptoms: a population-based study

    SciTech Connect (OSTI)

    Korn, R.J.; Dockery, D.W.; Speizer, F.E.; Ware, J.H.; Ferris, B.G.

    1987-01-01T23:59:59.000Z

    Data from a random sample of 8515 white adults residing in six cities in the eastern and midwestern United States were used to examine the relationships between occupational exposures to dust or to gases and fumes and chronic respiratory symptoms. 31% of the population had a history of occupational dust exposure and 30% reported exposure to gas or to fumes. After adjusting for smoking habits, age, gender, and city of residence, subjects with either occupational exposure had significantly elevated prevalence of chronic cough, chronic phlegm, persistent wheeze, and breathlessness. The adjusted relative odds of chronic respiratory symptoms for subjects exposed to dust ranged from 1.32 to 1.60. Subjects with gas or fume exposure had relative odds of symptoms between 1.27 and 1.43 when compared to unexposed subjects. Occupational dust exposure was associated with a higher prevalence of chronic obstructive pulmonary disease (COPD) as defined by an FEV1/FVC ratio of less than 0.6, when comparing exposed and unexposed participants (OR=1.53, 95% CI=1.17-2.08). Gas or fume exposure was associated with a small, but not significant, increase in COPD prevalence. Significant trends were noted for wheeze and phlegm with increasing duration of dust exposure. Although 36% of exposed subjects reported exposure to both dust and fumes, there was no evidence of a multiplicative interaction between the effects of the individual exposures. Smoking was a significant independent predictor of symptoms, but did not appear to modify the effect of dust or fumes on symptom reporting. These data, obtained in random samples of general populations, demonstrate that chronic respiratory disease can be independently associated with occupational exposures.

  20. Coordinating Pediatric Medical Care during an Influenza Pandemic - Hospital Workbook

    SciTech Connect (OSTI)

    HCTT CHE

    2010-01-01T23:59:59.000Z

    This workbook is intended to assist hospitals with coordinating medical care for pediatric influenza-like illness across their community.

  1. SDSU General Catalog 2013-2014 289 Hospitality and Tourism

    E-Print Network [OSTI]

    Gallo, Linda C.

    SDSU General Catalog 2013-2014 289 HTM Hospitality and Tourism Management In the L. Robert Payne School of Hospitality and Tourism Management In the College of Professional Studies and Fine Arts OFFICE for Professional Development: Jeffries Offered by the L. Robert Payne School of Hospitality and Tourism Management

  2. SDSU General Catalog 2011-2012 281 Hospitality and Tourism

    E-Print Network [OSTI]

    Gallo, Linda C.

    SDSU General Catalog 2011-2012 281 HTM Hospitality and Tourism Management In the College of Hospitality and Tourism Management Major in hospitality and tourism management with the B.S. degree in applied arts and sciences. Emphasis in global tourism management. Emphasis in hotel operations and management

  3. 178 SDSU General Catalog 2007-2008 Hospitality and Tourism

    E-Print Network [OSTI]

    Gallo, Linda C.

    178 SDSU General Catalog 2007-2008 Hospitality and Tourism Management In the College: 619-594-4443 http://www.sdsu.edu/htm Faculty Hospitality and Tourism Management is administered by the Hospitality and Tourism Management Program Committee. The program draws on courses offered by the faculty

  4. Camp counselors working with chronically ill children

    E-Print Network [OSTI]

    Fiala, Samuel E.

    2006-04-12T23:59:59.000Z

    ; and the relation between these individual characteristics and ratings of counselor efficacy was explored. Changes in counselors? knowledge of and/or attitudes toward chronically ill children after their camp experience were also examined. Results suggest that camp...

  5. Chronic respiratory effects of indoor formaldehyde exposure

    SciTech Connect (OSTI)

    Krzyzanowski, M.; Quackenboss, J.J.; Lebowitz, M.D.

    1990-01-01T23:59:59.000Z

    The relation of chronic respiratory symptoms and pulmonary function to formaldehyde (HCHO) in homes was studied in a sample of 298 children (6-15 years of age) and 613 adults. HCHO measurements were made with passive samplers two one-week periods. Data on chronic cough and phlegm, wheeze, attacks of breathlessness, and doctor diagnoses of chronic bronchitis and asthma were collected with self-completed questionnaires. Peak expiratory flow rates (PEFR) were obtained during the evenings and mornings for up to 14 consecutive days for each individual. Significantly greater prevalence rates of asthma and chronic bronchitis were found in children from houses with HCHO levels 60-120 ppb than in those less exposed, especially in children also exposed to environmental tobacco smoke. In children, levels of PEFR linearly decreased with HCHO exposure, with estimated decrease due to 60 ppb of HCHO equivalent to 22% of PEFR level in nonexposed children.

  6. Sorghum Diseases.

    E-Print Network [OSTI]

    Amador, Jose; Berry, Robert W.; Frederiksen, Richard A.; Horne, C. Wendell; Thames, Walter H.; Toler, Robert W.

    1969-01-01T23:59:59.000Z

    of organisms attacking seeds. Environmental conditions 1 encourage seed rot development also W~II increase the amount of damage caused by seedling disease. Vigorous seedlings produc:d from high-quality seed can withstand attack much better than low.... This fungus can cause considerable sorghum damage, although it usually is confined to individual fields or areas within fields that are occasionally flooded. Sorghum downy mildew, Sclerospora sorghi (Kulk) Weston & Uppal, was found first in Texas in 196...

  7. Disease-Specific Symptoms and Health-Related Quality of Life in Children and Adolescents with Inflammatory Bowel Disease

    E-Print Network [OSTI]

    Vaughan-Dark, Chelsea Ann

    2013-07-17T23:59:59.000Z

    , & Tennen, 2006). Therefore, HRQOL provides valuable information about patient outcomes in terms of successful adaptation to chronic illness (Livneh, 2001; Varni, Burwinkle, & Lane, 2005). Although HRQOL is a broad concept that may encompass a number...; Cortina, McGraw, deAlarcon, Rothenberg, & Drotar, 2010; Varni et al., 2006; Varni et al., 2007). Within the category of gastrointestinal disorders, Crohn?s disease and ulcerative colitis, two conditions subsumed under the overarching disease category...

  8. Invest in Your Bones Osteoporosis--The Silent Disease

    E-Print Network [OSTI]

    Invest in Your Bones Osteoporosis--The Silent Disease Leaflet 2 Osteoporosis, a painful of State Health Services, 2008). Osteoporosis is preventable and/or treatable. Accordingly, osteoporosis of height, and chronic back pain. Hip fracture, the most serious consequence of osteoporosis, threatens one

  9. E-Print Network 3.0 - adosado al hospital Sample Search Results

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    General Hospital EEG + Epilepsy in... -patient service Montreal Neurological Hospital Pediatric ... Source: Shoubridge, Eric - Montreal Neurological Institute, McGill...

  10. E-Print Network 3.0 - admitting department hospital Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Abstract (298 words) Hospital reform... private companies providing health care services: hospital design, medical equipment, ... Source: Ecole Polytechnique,...

  11. Hospital ventilation standards and energy conservation: chemical contamination of hospital air. Final report

    SciTech Connect (OSTI)

    Rainer, D.; Michaelsen, G.S.

    1980-03-01T23:59:59.000Z

    In an era of increasing energy conservation consciousness, a critical reassessment of the validity of hospital ventilation and thermal standards is made. If current standards are found to be excessively conservative, major energy conservation measures could be undertaken by rebalancing and/or modification of current HVAC systems. To establish whether or not reducing ventilation rates would increase airborne chemical contamination to unacceptable levels, a field survey was conducted to develop an inventory and dosage estimates of hospital generated airborne chemical contaminants to which patients, staff, and visitors are exposed. The results of the study are presented. Emphasis is on patient exposure, but an examination of occupational exposure was also made. An in-depth assessment of the laboratory air environment is documented. Housekeeping products used in survey hospitals, hazardous properties of housekeeping chemicals and probable product composition are discussed in the appendices.

  12. Patterns of health and disease have undergone dramatic transitions during human history, reflecting social and

    E-Print Network [OSTI]

    Vermont, University of

    of infectious disease and infant mortality decreased, lengthening life expectancy.At the same time,noninfectious chronic disease rose, accounting for a greater share of over- all mortality. Greater water and air dispersed into new habitats by phoresy (i.e.,one organism transporting another), flight, or wind, but human

  13. Digit frequency in the hospital! Designing for the task: What numbers are really used in hospitals?!

    E-Print Network [OSTI]

    Subramanian, Sriram

    .wiseman@cs.ucl.ac.uk The task and the problem! Medical workers program infusion pumps to administer drug treatments to patients. This involves entering the volume and rate of medication to be infused. ! ! Occasionally errors are made during into infusion pumps on the ward? Logs from pumps were collected from four different wards in one hospital

  14. Jackson Park Hospital Green Building Medical Center

    SciTech Connect (OSTI)

    William Dorsey; Nelson Vasquez

    2010-03-31T23:59:59.000Z

    Jackson Park Hospital completed the construction of a new Medical Office Building on its campus this spring. The new building construction has adopted the City of Chicago's recent focus on protecting the environment, and conserving energy and resources, with the introduction of green building codes. Located in a poor, inner city neighborhood on the South side of Chicago, Jackson Park Hospital has chosen green building strategies to help make the area a better place to live and work. The new green building houses the hospital's Family Medicine Residency Program and Specialty Medical Offices. The residency program has been vital in attracting new, young physicians to this medically underserved area. The new outpatient center will also help to allure needed medical providers to the community. The facility also has areas designated to women's health and community education. The Community Education Conference Room will provide learning opportunities to area residents. Emphasis will be placed on conserving resources and protecting our environment, as well as providing information on healthcare access and preventive medicine. The new Medical Office Building was constructed with numerous energy saving features. The exterior cladding of the building is an innovative, locally-manufactured precast concrete panel system with integral insulation that achieves an R-value in excess of building code requirements. The roof is a 'green roof' covered by native plantings, lessening the impact solar heat gain on the building, and reducing air conditioning requirements. The windows are low-E, tinted, and insulated to reduce cooling requirements in summer and heating requirements in winter. The main entrance has an air lock to prevent unconditioned air from entering the building and impacting interior air temperatures. Since much of the traffic in and out of the office building comes from the adjacent Jackson Park Hospital, a pedestrian bridge connects the two buildings, further decreasing the amount of unconditioned air that enters the office building. The HVAC system has an Energy Efficiency Rating 29% greater than required. No CFC based refrigerants were used in the HVAC system, thus reducing the emission of compounds that contribute to ozone depletion and global warming. In addition, interior light fixtures employ the latest energy-efficient lamp and ballast technology. Interior lighting throughout the building is operated by sensors that will automatically turn off lights inside a room when the room is unoccupied. The electrical traction elevators use less energy than typical elevators, and they are made of 95% recycled material. Further, locally manufactured products were used throughout, minimizing the amount of energy required to construct this building. The primary objective was to construct a 30,000 square foot medical office building on the Jackson Park Hospital campus that would comply with newly adopted City of Chicago green building codes focusing on protecting the environment and conserving energy and resources. The energy saving systems demonstrate a state of the-art whole-building approach to energy efficient design and construction. The energy efficiency and green aspects of the building contribute to the community by emphasizing the environmental and economic benefits of conserving resources. The building highlights the integration of Chicago's new green building codes into a poor, inner city neighborhood project and it is designed to attract medical providers and physicians to a medically underserved area.

  15. Energy Star for Hospitals 2011 Update: Progression or Regression?

    E-Print Network [OSTI]

    Travis, B.

    2012-01-01T23:59:59.000Z

    Energy Star for Hospitals 2011 Update: Progression or Regression? Brandon E. Travis1 1 Project Manager, SSRCx, 2995 Sidco Drive, Nashville, TN 37204, U.S.A. Email: btravis@ssr-inc.com Abstract: The Energy Star performance rating system...ENERGY STAR for Hospitals 2011 Update: Progression or Regression? Brandon E. Travis October 24, 2012 History of Energy Star Energy Star for Hospitals Critique & Conclusions Outline ? Benchmarks are important ? Energy efficiency void...

  16. Department of Energy Announces the Launch of the Hospital Energy...

    Energy Savers [EERE]

    of advanced energy efficiency and renewable technologies in hospital design, construction, retrofit, operations, and maintenance. DOE's Richard F. Moorer joined American...

  17. Hospital Energy Benchmarking Guidance - Version 1.0

    E-Print Network [OSTI]

    Singer, Brett C.

    2010-01-01T23:59:59.000Z

    ventilation site energy intensity of California hospitalsSep-2009 Lighting site energy intensity for all Californiafor lighting site energy intensity of California nursing

  18. asistieron al hospital: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Summary: Nosocomial transmission of pertussis in hospitals among patients, health care workers (HCWs), or both, poses a high risk of transmission to children without immunity...

  19. Building Green in Greensburg: Kiowa County Memorial Hospital

    Office of Energy Efficiency and Renewable Energy (EERE)

    This poster highlights energy efficiency, renewable energy, and sustainable features of the high-performing Kiowa County Memorial Hospital building in Greensburg, Kansas.

  20. Hospital Energy Benchmarking Guidance - Version 1.0

    E-Print Network [OSTI]

    Singer, Brett C.

    2010-01-01T23:59:59.000Z

    important for the cooling system (supply and return flows)hospital building - Cooling water supply/return from centralhospital building - Cooling water supply/return from central

  1. acutely hospitalized elderly: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Samaritan Hospital, an acute-care medical facility to a nationally recognized leader in health care. By leveraging its core competency of building loyal, features the highest...

  2. acute public hospitals: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Samaritan Hospital, an acute-care medical facility to a nationally recognized leader in health care. By leveraging its core competency of building loyal, features the highest...

  3. acute care hospital: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Samaritan Hospital, an acute-care medical facility to a nationally recognized leader in health care. By leveraging its core competency of building loyal, features the highest...

  4. acute care hospitals: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Samaritan Hospital, an acute-care medical facility to a nationally recognized leader in health care. By leveraging its core competency of building loyal, features the highest...

  5. acute hospital services: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Samaritan Hospital, an acute-care medical facility to a nationally recognized leader in health care. By leveraging its core competency of building loyal, features the highest...

  6. Particulate matter and heart disease: Evidence from epidemiological studies

    SciTech Connect (OSTI)

    Peters, Annette [GSF-National Research Center for Environment and Health, Institute of Epidemiology, Ingolstaedter Landstr. 1, 85764 Neuherberg (Germany)]. E-mail: peters@gsf.de

    2005-09-01T23:59:59.000Z

    The association between particulate matter and heart disease was noted in the mid-nineties of last century when the epidemiological evidence for an association between air pollution and hospital admissions due to cardiovascular disease accumulated and first hypotheses regarding the pathomechanism were formulated. Nowadays, epidemiological studies have demonstrated coherent associations between daily changes in concentrations of ambient particles and cardiovascular disease mortality, hospital admission, disease exacerbation in patients with cardiovascular disease and early physiological responses in healthy individuals consistent with a risk factor profile deterioration. In addition, evidence was found that annual average PM{sub 2.5} exposures are associated with increased risks for mortality caused by ischemic heart disease and dysrhythmia. Thereby, evidence is suggesting not only a short-term exacerbation of cardiovascular disease by ambient particle concentrations but also a potential role of particles in defining patients' vulnerability to acute coronary events. While this concept is consistent with the current understanding of the factors defining patients' vulnerability, the mechanisms and the time-scales on which the particle-induced vulnerability might operate are unknown.

  7. Systemic lupus erythematosus with generalized chronic cutaneous (discoid) lupus erythematosus

    E-Print Network [OSTI]

    Dadlani, Chicky; Pulitzer, Melissa; Prystowsky, Stephen D

    2008-01-01T23:59:59.000Z

    lupus erythematosus (DLE): a clinical and laboratoryLE. Chronic cutaneous DLE affects twice as many women as it2 ]. Chronic cutaneous DLE begins as red-purple macules,

  8. Chronic respiratory effects of indoor formaldehyde exposure

    SciTech Connect (OSTI)

    Krzyzanowski, M.; Quackenboss, J.J.; Lebowitz, M.D. (Univ. of Arizona Health Sciences Center, Tucson (USA))

    1990-08-01T23:59:59.000Z

    The relation of chronic respiratory symptoms and pulmonary function to formaldehyde (HCHO) in homes was studied in a sample of 298 children (6-15 years of age) and 613 adults. HCHO measurements were made with passive samplers during two 1-week periods. Data on chronic cough and phlegm, wheeze, attacks of breathlessness, and doctor diagnoses of chronic bronchitis and asthma were collected with self-completed questionnaires. Peak expiratory flow rates (PEFR) were obtained during the evenings and mornings for up to 14 consecutive days for each individual. Significantly greater prevalence rates of asthma and chronic bronchitis were found in children from houses with HCHO levels 60-120 ppb than in those less exposed, especially in children also exposed to environmental tobacco smoke. In children, levels of PEFR decreased linearly with HCHO exposure, with the estimated decrease due to 60 ppb of HCHO equivalent to 22% of PEFR level in nonexposed children. The effects in asthmatic children exposed to HCHO below 50 ppb were greater than in healthy ones. The effects in adults were less evident: decrements in PEFR due to HCHO over 40 ppb were seen only in the morning, and mainly in smokers.

  9. HOSPITALITY AND TOURISM MANAGEMENT MAJOR Virgu1iaTech

    E-Print Network [OSTI]

    Virginia Tech

    Hospitality Facilities Planning and Methods I (3) Management (3) #HTM 3484 Socio-Cultural Impacts of Tourism 4414 Food and Beverage Management (Pre: HTM 3414) * #HTM 4464 Human Resources Management in HospHOSPITALITY AND TOURISM MANAGEMENT MAJOR Virgu1iaTech Panplil College of BusIness Department

  10. Evaluation of Miscellaneous and Electronic Device Energy Use in Hospitals

    E-Print Network [OSTI]

    1 Evaluation of Miscellaneous and Electronic Device Energy Use in Hospitals Douglas R and Electronic Device Energy Use in Hospitals Douglas R. Black*, Steven M. Lanzisera, Judy Lai, Richard E. Brown@lbl.gov, REBrown@lbl.gov, and BCSinger@lbl.gov *Corresponding Author Abstract: Miscellaneous and electronic loads

  11. Polish-American Children's Hospital in Krakow, Poland

    SciTech Connect (OSTI)

    Secrest, T.J.; Szydlowski, R.F. (Pacific Northwest Lab., Richland, WA (United States)); Wade, D. (RDA Engineering, Inc., Marietta, GA (United States))

    1993-03-01T23:59:59.000Z

    In late 1990 staff from the US Department of Energy's Office of Technical and Financial Assistance identified the Polish-American Children's Hospital as a potential site for application of DOE expertise to reduce the Hospital's energy requirements. Visits to the hospital in the fall and winter of 1991--1992 provided initial scoping of the energy related activities that would be supported by DOE. In addition to reducing energy requirements, the Hospital staff expressed a need for assistance in the areas of power quality and medical waste incineration. Subsequently, a power quality study supported by the Electric Power and Research Institute has been initiated and medical waste incineration will be provided by a Polish organization. The resulting scope of work for this effort is to survey the Hospital's thermal energy supply and demand systems to identify no-cost and low-cost measures that will reduce the Hospital's energy requirements. Applicable measures would then be demonstrated in the Hospital through a partnership with US and Polish organizations and a sister hospital in the United States.

  12. Dimensioning hospital wards using the Erlang loss model Corresponding author

    E-Print Network [OSTI]

    -2006. Finally, we demonstrate the efficiency of merging departments. Keywords: hospital resource allocationDimensioning hospital wards using the Erlang loss model Corresponding author: A.M. de Bruin (MSc of Sciences Department of Mathematics Assistant professor Optimization of Business Processes L. van Zanten

  13. SDSU General Catalog 2009-2010 263 Hospitality and Tourism

    E-Print Network [OSTI]

    Gallo, Linda C.

    SDSU General Catalog 2009-2010 263 HTM Hospitality and Tourism Management In the College Offered by the School Major in hospitality and tourism management with the B.S. degree in applied arts and sciences. Emphasis in global tourism management. Emphasis in hotel operations and management. Emphasis

  14. 282 SDSU General Catalog 2010-2011 Hospitality and Tourism

    E-Print Network [OSTI]

    Gallo, Linda C.

    282 SDSU General Catalog 2010-2011 Hospitality and Tourism Management In the College and tourism management with the B.S. degree in applied arts and sciences. Emphasis in global tourism and management. The Major Hospitality and tourism management is an interdisciplinary major which culminates

  15. E-Print Network 3.0 - acute hospital bed Sample Search Results

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Orlando, FL Summary: Downtown Naples Hospital Naples Acute Care 420 2,815.7 12;18 County Hospital Name City Type Number Beds... Hospital Clearwater Acute Care 687 2,130.9...

  16. Automated Detection of Infectious Disease Outbreaks in Hospitals: A Retrospective Cohort Study

    E-Print Network [OSTI]

    2010-01-01T23:59:59.000Z

    MRSA) Antibiotic profile N S. aureus (MRSA) Ward N S.aureus (MRSA) Ward Y S.aureus (MRSA) d Ward N S. aureus (MRSA) d Service N S.

  17. Title: Chronic hepatitis C virus infection: does it really impact health-related quality of life? A study in rural Egypt.

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    of life? A study in rural Egypt. Michaël Schwarzinger1 , Sahar Dewedar2 , Claire Rekacewicz3 , Khaled, Faculty of Medicine, Ain Shams University, Cairo, Egypt, 3 Emerging Disease Epidemiology Unit, Institut chronically infected with HCV in rural Egypt and a higher morbidity amongst uninfected controls as compared

  18. E-Print Network 3.0 - army surgical hospital Sample Search Results

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Surgeon. Trained by Summary: ). Ran military hospital at Renkioi, influenced by Nightingale. Became Chair of Hygiene at Army Medical... , St Thomas's Hospital, Examiner, Mas-...

  19. HARVARD UNIVERSITY HOSPITALITY & DINING SERVICES Sustainability Report 2010

    E-Print Network [OSTI]

    Paulsson, Johan

    on sustainability in research and teaching, the Report Card examines colleges and universities, as institutions into account geographic region." From the College Sustainability Report Card website: wwwHARVARD UNIVERSITY HOSPITALITY & DINING SERVICES Sustainability Report 2010 #12

  20. ORNL retiree recalls 1944 hospital bombing in Belgium | ornl...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    wore in 1944 when the hospital he was working in as a medic in Belgium was hit with a German bomb. Shepherd -- 89 years old and an ORNL retiree who treated wounded from the D-Day...

  1. Improving product availability in hospitals : the role of inventory inaccuracies

    E-Print Network [OSTI]

    Opolon, David C. (David Cyrille)

    2010-01-01T23:59:59.000Z

    All players in the healthcare industry face increasing public and political pressure to improve quality of care and control costs. Hospitals, on the frontline of this challenge, face nursing shortages and financial ...

  2. THE UNIVERSITY OF CONNECTICUT HEALTH CENTER JOHN DEMPSEY HOSPITAL

    E-Print Network [OSTI]

    Oliver, Douglas L.

    Mandibular condyle prosthesis Operating Room Temporomandibular joint (TMJ) prosthesis Operating Room. PROCEDURE: A. DELEGATION OF RESPONSIBILITY & OFFICIAL CONTACT PERSON The Chief Operating Officer for John: Chief Operating Officer for John Dempsey Hospital UCHC Safety Officer Director of Clinical Engineering

  3. Application of Thermal Storage, Peak Shaving and Cogeneration for Hospitals

    E-Print Network [OSTI]

    McClure, J. D.; Estes, J. M.; Estes, M. C.

    1987-01-01T23:59:59.000Z

    Energy costs of hospitals can be managed by employing various strategies to control peak electrical demand (KW) while at the same time providing additional security of operation in the event that an equipment failure or a disruption of power from...

  4. Better than CFL? Dimmable LED Downlights in Hospitality Facilities Webinar

    Broader source: Energy.gov [DOE]

    LEDs represent less than 1% of the installed base of U.S. downlights, which in 2012 numbered about 700 million. In hospitality facilities, past efforts to reduce lighting energy use have mainly...

  5. I am extremely pleased to extend my greetings on the publication of Kyoto University Hospital's Guidance 2013. Kyoto University Hospital

    E-Print Network [OSTI]

    Takada, Shoji

    robot Da Vinci has been operating smoothly, and is producing solid results. The Rheumatism Center. Meanwhile, the Division for iPS Cell Application Development, which was set up inside the hospital in 2011

  6. A case report of motor neuron disease in a patient showing significant level of DDTs, HCHs and organophosphate metabolites in hair as well as levels of hexane and toluene in blood

    SciTech Connect (OSTI)

    Kanavouras, Konstantinos [Department of Neurology, Medical School, University of Crete, Heraklion, Crete (Greece)] [Department of Neurology, Medical School, University of Crete, Heraklion, Crete (Greece); Tzatzarakis, Manolis N. [Center of Toxicology Science and Research, University of Crete, Heraklion, Crete (Greece)] [Center of Toxicology Science and Research, University of Crete, Heraklion, Crete (Greece); Mastorodemos, Vasileios; Plaitakis, Andreas [Department of Neurology, Medical School, University of Crete, Heraklion, Crete (Greece)] [Department of Neurology, Medical School, University of Crete, Heraklion, Crete (Greece); Tsatsakis, Aristidis M., E-mail: aris@med.uoc.gr [Center of Toxicology Science and Research, University of Crete, Heraklion, Crete (Greece)

    2011-11-15T23:59:59.000Z

    Motor neuron disease is a devastating neurodegenerative condition, with the majority of sporadic, non-familial cases being of unknown etiology. Several epidemiological studies have suggested that occupational exposure to chemicals may be associated with disease pathogenesis. We report the case of a patient developing progressive motor neuron disease, who was chronically exposed to pesticides and organic solvents. The patient presented with leg spasticity and developed gradually clinical signs suggestive of amyotrophic lateral sclerosis, which was supported by the neurophysiologic and radiological findings. Our report is an evidence based case of combined exposure to organochlorine (DDTs), organophosphate pesticides (OPs) and organic solvents as confirmed by laboratory analysis in samples of blood and hair confirming systematic exposure. The concentration of non-specific dialkylphosphates metabolites (DAPs) of OPs in hair (dimethyphopshate (DMP) 1289.4 pg/mg and diethylphosphate (DEP) 709.4 pg/mg) and of DDTs (opDDE 484.0 pg/mg, ppDDE 526.6 pg/mg, opDDD 448.4 pg/mg, ppDDD + opDDT 259.9 pg/mg and ppDDT 573.7 pg/mg) were considerably significant. Toluene and n-hexane were also detected in blood on admission at hospital and quantified (1.23 and 0.87 {mu}g/l, respectively), while 3 months after hospitalization blood testing was found negative for toluene and n-hexane and hair analysis was provided decrease levels of HCHs, DDTs and DAPs. -- Highlights: Black-Right-Pointing-Pointer Exposure to pesticides and organic solvents might be a risk factor for sporadic MND. Black-Right-Pointing-Pointer We report a patient who developed progressive upper and lower motor neuron disease. Black-Right-Pointing-Pointer The patient had a history of occupational exposure to pesticides and solvents. Black-Right-Pointing-Pointer High DDTs' levels and increased levels of DMP and DEP were measured in his hair. Black-Right-Pointing-Pointer The patients' exposure to chemicals might have played a role in MND development.

  7. From the Constitution to the Hospital: Universal Health Care in Thailand 

    E-Print Network [OSTI]

    Mattison, Shawn

    2007-01-01T23:59:59.000Z

    in Implementing Quality Management Systems in Thailand: Asystem requires accredited hospitals to apply Total Quality Management (

  8. Chronic renal failure with gout: a marker of chronic lead poisoning

    SciTech Connect (OSTI)

    Craswell, P.W.; Price, J.; Boyle, P.D.; Heazlewood, V.J.; Baddeley, H.; Lloyd, H.M.; Thomas, B.J.; Thomas, B.W.

    1984-09-01T23:59:59.000Z

    EDTA (calcium disodium edetate) lead mobilization and x-ray fluorescence (XRF) finger bone lead tests were done in 42 patients with chronic renal failure and without persisting lead intoxication. Nineteen of 23 patients with gout and 8 of 19 without gout had positive EDTA lead mobilization tests. Those patients with gout excreted significantly more excess lead chelate than those without gout. In the gout group 17 patients denied any childhood or industrial exposure to lead. They had a greater number of positive tests and excreted significantly more excess lead chelate than 14 patients with neither gout nor lead exposure. These results confirm that gout in the presence of chronic renal failure is a useful marker of chronic lead poisoning. Of 27 patients with positive lead mobilization tests, only 13 had elevated XRF finger bone lead concentrations (sensitivity 48%). Three of 15 patients with negative lead mobilization tests had elevated XRF finger bone lead concentrations (specificity 80%). Although the XRF finger bone lead test is a convenient noninvasive addition to the diagnostic evaluation of patients with chronic renal failure and gout, its application is limited due to the lack of sensitivity of the method.

  9. ameliorates chronic epicutaneous: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    obstructive uropathy.Autonomic neuropathy is well associated with chronic renal failure patients. Knowledge of autonomic dysfunction canencourage patients and physicians to...

  10. ameliorates chronic hyperprolactinemia: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    obstructive uropathy.Autonomic neuropathy is well associated with chronic renal failure patients. Knowledge of autonomic dysfunction canencourage patients and physicians to...

  11. Costs of chronic disease and an alternative to reduce these costs: case study of End Stage Renal Disease (ESRD)

    E-Print Network [OSTI]

    Jang, Won-Ik

    2005-02-17T23:59:59.000Z

    the efficiency of water supply systems taking into account water pricing, marketing, and treatment costs is proposed. This system treats and supplies water differently depending on the source of the water and if the end-use of the water is a potable or non...

  12. Reproductive Diseases in Cattle

    E-Print Network [OSTI]

    Sprott, L. R.; Field, Bob

    1998-12-03T23:59:59.000Z

    This publication describes prevention measures, symptoms, diagnosis and treatment options for the most common reproductive diseases in cattle: brucellosis (Bang's disease); leptospirosis; infectious bovine rhinotracheitis (IBR) and bovine diarrhea...

  13. Management of Low-Level Radioactive Waste from Research, Hospitals and Nuclear Medical Centers in Egypt - 13469

    SciTech Connect (OSTI)

    Hasan, M.A.; Selim, Y.T.; Lasheen, Y.F. [Hot Labs and Waste Management Center, Atomic Energy Authority, 3 Ahmed El-Zomor St., El-Zohour District, Naser City, 11787, Cairo (Egypt)] [Hot Labs and Waste Management Center, Atomic Energy Authority, 3 Ahmed El-Zomor St., El-Zohour District, Naser City, 11787, Cairo (Egypt)

    2013-07-01T23:59:59.000Z

    The application of radioisotopes and radiation sources in medical diagnosis and therapy is an important issue. Physicians can use radioisotopes to diagnose and treat diseases. Methods of treatment, conditioning and management of low level radioactive wastes from the use of radiation sources and radioisotopes in hospitals and nuclear medicine application, are described. Solid Radioactive waste with low-level activity after accumulation, minimization, segregation and measurement, are burned or compressed in a compactor according to the international standards. Conditioned drums are transported to the interim storage site at the Egyptian Atomic Energy Authority (EAEA) represented in Hot Labs and Waste Management Center (HLWMC) for storage and monitoring. (authors)

  14. Dynamical changes in neurological diseases and anesthesia Michelle M McCarthy1

    E-Print Network [OSTI]

    Kopell, Nancy

    Dynamical changes in neurological diseases and anesthesia Michelle M McCarthy1 , ShiNung Ching1 within the networks known to be relevant to each disorder. We also discuss anesthesia, since Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, 55 Fruit St., GRJ

  15. SymposiumClinical Research Priority Program University of Zurich "Viral Infectious Diseases"

    E-Print Network [OSTI]

    Zürich, Universität

    of Biosystems Science and Engineering (BSSE), ETH Zurich 15:25 Coffee break Part II: Metagenomics ­ ChairSymposiumClinical Research Priority Program ­ University of Zurich "Viral Infectious Diseases:00 Great Lecture Hall WEST, UniversityHospital Zurich, Raemistrasse 100, Zurich 14:00 Welcome

  16. Evaluation of the serum catalase and myeloperoxidase activities in chronic arsenic-exposed individuals and concomitant cytogenetic damage

    SciTech Connect (OSTI)

    Banerjee, Mayukh; Banerjee, Nilanjana; Ghosh, Pritha [Molecular and Human Genetics Division, Indian Institute of Chemical Biology, Kolkata (India); Das, Jayanta K. [Department of Dermatology, West Bank Hospital, Howrah (India); Basu, Santanu [Department of General Medicine, Sri Aurobindo Seva Kendra, Kolkata (India); Sarkar, Ajoy K. [Peerless Hospital and B.K Roy Research Centre, Kolkata (India); States, J. Christopher, E-mail: jcstates@louisville.ed [Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY (United States); Center for Environmental Genomics and Integrative Biology, University of Louisville, Louisville, KY (United States); Giri, Ashok K., E-mail: akgiri15@yahoo.co [Molecular and Human Genetics Division, Indian Institute of Chemical Biology, Kolkata (India)

    2010-11-15T23:59:59.000Z

    Chronic arsenic exposure through contaminated drinking water is a major environmental health issue. Chronic arsenic exposure is known to exert its toxic effects by a variety of mechanisms, of which generation of reactive oxygen species (ROS) is one of the most important. A high level of ROS, in turn, leads to DNA damage that might ultimately culminate in cancer. In order to keep the level of ROS in balance, an array of enzymes is present, of which catalase (CAT) and myeloperoxidase (MPO) are important members. Hence, in this study, we determined the activities of these two enzymes in the sera and chromosomal aberrations (CA) in peripheral blood lymphocytes in individuals exposed and unexposed to arsenic in drinking water. Arsenic in drinking water and in urine was used as a measure of exposure. Our results show that individuals chronically exposed to arsenic have significantly higher CAT and MPO activities and higher incidence of CA. We found moderate positive correlations between CAT and MPO activities, induction of CA and arsenic in urine and water. These results indicate that chronic arsenic exposure causes higher CAT and MPO activities in serum that correlates with induction of genetic damage. We conclude that the serum levels of these enzymes might be used as biomarkers of early arsenic exposure induced disease much before the classical dermatological symptoms of arsenicosis begin to appear.

  17. Cardiovascular Disease (CVD) Coronary heart disease

    E-Print Network [OSTI]

    Dever, Jennifer A.

    have a greater prevalence in women · Osteoporosis · Autoimmune disease A. Osteoporosis · Osteoporosis ­ disorder of low bone mass, microarchitectural denegra7on% of all women >65 years old have osteoporosis (15% of all Caucasian women

  18. Using Wikipedia to forecast diseases

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Using Wikipedia to forecast diseases Using Wikipedia to forecast diseases Scientists can now monitor and forecast diseases around the globe more effectively by analyzing views of...

  19. Evaluation of Acute and Chronic Lesions in Percutaneous Coronary Intervention

    E-Print Network [OSTI]

    Roberts, Aaron

    2012-10-19T23:59:59.000Z

    EVALUATION OF ACUTE AND CHRONIC LESIONS IN PERCUTANEOUS CORONARY INTERVENTION A Thesis by AARON WHEELER ROBERTS Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements... for the degree of MASTER OF SCIENCE August 2012 Major Subject: Biomedical Sciences Evaluation of Acute and Chronic Lesions in Percutaneous Coronary Intervention Copyright 2012 Aaron Wheeler Roberts...

  20. Evaluation of Miscellaneous and Electronic Device Energy Use in Hospitals

    SciTech Connect (OSTI)

    Black, Douglas R.; Lanzisera, Steven M.; Lai, Judy; Brown, Richard E.; Singer, Brett C.

    2012-09-01T23:59:59.000Z

    Miscellaneous and electronic loads (MELs) consume about one-thirdof the primary energy used in US buildings, and their energy use is increasing faster than other end-uses. In healthcare facilities, 30percent of the annual electricity was used by MELs in 2008. This paper presents methods and challenges for estimating medical MELs energy consumption along with estimates of energy use in a hospital by combining device-level metered data with inventories and usage information. An important finding is that common, small devices consume large amounts of energy in aggregate and should not be ignored when trying to address hospital energy use.

  1. Review Article Chronic Cough, Reflux, Postnasal Drip Syndrome, and

    E-Print Network [OSTI]

    The Otolaryngologist; Deborahc. Sylvester; Petros D. Karkos; James Johnston; Raghav C. Dwivedi; Helen Atkinson; Shah Kortequee

    2012-01-01T23:59:59.000Z

    License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Objectives. Chronic cough is a multifactorial symptom that requires multidisciplinary approach. Over the last years, general practitioners refer increasingly more chronic cough patients directly to the otolaryngologist. The aim of this paper is to highlight the issues in diagnosis and management of chronic cough patients from the otolaryngologist perspective. Design. Literature review. Results. Gastroesophageal reflux and postnasal drip syndrome remain one of the most common causes of chronic cough. Better diagnostic modalities, noninvasive tests, and high technology radiological and endoscopic innovations have made diagnosis of these difficult-to-treat patients relatively easier. Multidisciplinary assessment has also meant that at least some of these cases can be dealt with confidently in one stop clinics. Conclusions. As the number of referrals of chronic cough patients to an Ear Nose Throat Clinic increases, the otolaryngologist plays a pivotal role in managing these difficult cases. 1.

  2. The role of prior exercise in chronic obstructive pulmonary disease and recovery

    E-Print Network [OSTI]

    Chao, Peter Weiyen

    2010-01-01T23:59:59.000Z

    and increased risk of heart attack, stroke and cancer 55 .in the past three months • a heart attack in the last threepast three months a heart attack in the last three months

  3. What should be the blood pressure target for patients with chronic kidney disease?

    E-Print Network [OSTI]

    Nicholas, Susanne B.; Vaziri, Nosratola D.; Norris, Keith C.

    2013-01-01T23:59:59.000Z

    Treatment to Prevent Heart Attack Trial. Major outcomes inTreatment to Prevent Heart Attack Trial (ALLHAT). JAMA.Treatment to Prevent Heart Attack Trial (ALLHAT). Arch

  4. @neurIST Chronic Disease Management through Integration of Heterogeneous Data

    E-Print Network [OSTI]

    Frangi, Alejandro

    the generic requirements of the @neurIST system and presents the innovative work in distributing executable. Iavindrasanai , R.D. Hosej , A.F. Frangik , on behalf of the @neurIST Consortium a Infermed, UK b GridSystems S of Vienna, Vienna, Austria f B3C BioComputing Competence Centre, Bologna, Italy g Fraunhofer Institute, Bonn

  5. Highly Efficient Amplification of Chronic Wasting Disease Agent by Protein Misfolding Cyclic Amplification with

    E-Print Network [OSTI]

    Amplification with Beads (PMCAb) Chad J. Johnson1 , Judd M. Aiken2 , Debbie McKenzie2 , Michael D. Samuel3. Citation: Johnson CJ, Aiken JM, McKenzie D, Samuel MD, Pedersen JA (2012) Highly Efficient Amplification

  6. Quality Adjustment for Health Care Spending on Chronic Disease: Evidence from Diabetes Treatment, 1999–2009

    E-Print Network [OSTI]

    Eggleston, Karen N

    Although US health care expenditures reached 17.6 percent of GDP in 2009, quality measurement in this important service sector remains limited. Studying quality changes associated with 11 years of health care for patients ...

  7. Use of a Soluble Epoxide Hydrolase Inhibitor in Smoke-Induced Chronic Obstructive Pulmonary Disease

    E-Print Network [OSTI]

    Hammock, Bruce D.

    Lei Wang1, Jun Yang2, Lei Guo1, Dale Uyeminami1, Hua Dong2, Bruce D. Hammock2, and Kent E. Pinkerton1, and enhanced biosynthesis of oxidized lipids (3­6). According to a commonly held belief, anti-inflammatory ther

  8. Bone mineral density and fractures in older men with chronic obstructive pulmonary disease or asthma

    E-Print Network [OSTI]

    Dam, T.-T.; Harrison, S.; Fink, H. A.; Ramsdell, J.; Barrett-Connor, E.

    2010-01-01T23:59:59.000Z

    risk of vertebral osteoporosis compared to men with noto identify patients with osteoporosis. Keywords Bone loss .associated with COPD, osteoporosis is believed to affect 36%

  9. Prediction of Chronic Obstructive Pulmonary Disease (COPD) in Asthma Patients Using Electronic Medical Records

    E-Print Network [OSTI]

    Dai, Yi

    Objective: Identify clinical factors that modulate the risk of progression to COPD among asthma patients using data extracted from electronic medical records.

  10. New Functional Imaging Technology to Differentiate between Chronic Obstructive Pulmonary Disease and Heart Failure

    E-Print Network [OSTI]

    Pollack, Charles V.; Slattery, David E

    2011-01-01T23:59:59.000Z

    improvement of congestive heart failure: a pilot study. BMCtesting and the accuracy of heart failure diagnosis in theemergency department. Circ Heart Fail. 2010 Jan;3(1):104-10.

  11. Self-management skills in adolescents with chronic rheumatic disease: A cross-sectional survey

    E-Print Network [OSTI]

    Lawson, Erica F; Hersh, Aimee O; Applebaum, Mark A; Yelin, Edward H; Okumura, Megumi J; von Scheven, Emily

    2011-01-01T23:59:59.000Z

    management. Keywords: Self-management, transition, pediatricmanagement should be integrated into standardized transitionself-management is a critical part of this transition. This

  12. Update on the Hanford Site Chronic Beryllium Disease Prevention Program (CBDPP)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear SecurityTensile Strain Switched Ferromagnetism inS-4500II Field Emission SEM with EDAX (For3WebinarUpdateUpdate

  13. Update on the Hanford Site Chronic Beryllium Disease Prevention Program (CBDPP)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear SecurityTensile Strain Switched Ferromagnetism inS-4500II Field Emission SEM with EDAX (For3WebinarUpdateUpdateMay 9,

  14. Independent Oversight Inspection of the Hanford Site Chronic Beryllium Disease Prevention Program

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation ProposedUsingFun withconfinementEtching.348 270Energy Innovation Portal

  15. ATTACHMENT 1: HANFORD SITE CHRONIC BERYLLIUM DISEASE PREVENTION PROGRAM (CBDPP) COMMITTEE CHARTER

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth (AOD)Productssondeadjustsondeadjust DocumentationARMStreamsUSBudget AdvancedASSESSING AND9NOV98: HANFORD SITE

  16. E-Print Network 3.0 - attenuates chronic ciclosporin Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Accumulating evidence indicates that chronic pain provokes... after peripheral nerve injury. Brain imaging in patients with chronic pain demonstrates a decrease Source: Apkarian,...

  17. antigen-positive chronic hepatitis: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Summary: ??abstractChronic hepatitis C virus infection (HCV) affects 180 million people worldwide. Chronic HCV can cause hepatic decompensation, hepatocellular carcinoma...

  18. E-Print Network 3.0 - accurately diagnosing chronic Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    We therefore focus on mining measurement data to effectively diagnose chronic network... Troubleshooting Chronic Conditions in Large IP Networks (Paper ID: ... Source: Fisher,...

  19. What can I do with this degree? Clinical Nutrition Hospitals

    E-Print Network [OSTI]

    Escher, Christine

    speaking skills. FOOD SERVICE MANAGEMENT Includes: Menu Planning Budgeting Purchasing Food Preparation Obtain work experience in any large-scale food service operation such as campus cafeterias. Take business Service Indian Health Service Food & Drug Administration St. Elizabeth's Hospital National Center

  20. Coming to a hospital near you: mass spectrometry imaging

    SciTech Connect (OSTI)

    Bowen, Ben

    2013-10-31T23:59:59.000Z

    Berkeley Lab's Ben Bowen discusses "Coming to a hospital near you: mass spectrometry imaging" in this Oct. 28, 2013 talk, which is part of a Science at the Theater event entitled Eight Big Ideas. Go here to watch the entire event with all 8 speakers.

  1. Coming to a hospital near you: mass spectrometry imaging

    ScienceCinema (OSTI)

    Bowen, Ben

    2014-06-24T23:59:59.000Z

    Berkeley Lab's Ben Bowen discusses "Coming to a hospital near you: mass spectrometry imaging" in this Oct. 28, 2013 talk, which is part of a Science at the Theater event entitled Eight Big Ideas. Go here to watch the entire event with all 8 speakers.

  2. Ownership and Hospital Productivity Brigitte Dormont* et Carine Milcent**

    E-Print Network [OSTI]

    Ownership and Hospital Productivity Brigitte Dormont* et Carine Milcent** 1 July, 12, 2012 Abstract quality. This paper proposes an analysis of the differences in productivity and efficiency between French between these two sectors. The purpose of this paper is to compare the productivity of public and private

  3. One of John Dempsey Hospital's new quality improvement tools

    E-Print Network [OSTI]

    Oliver, Douglas L.

    One of John Dempsey Hospital's new quality improvement tools borrows lessons learned from the nuclear power industry, manufac turing and aviation. "Safety is a science. Reliability is a science, is a former Navy pilot. "We're learning specific tools based on high reliability tech niques to improve

  4. Evaluation of exposures of hospital employees to anesthetic gases

    SciTech Connect (OSTI)

    Lambeth, J.D.

    1988-01-01T23:59:59.000Z

    Hospital employees who work in hospital operating and recovery rooms are often exposed to a number of anesthetic gases. There is evidence to support the belief that such exposures have led to higher rates of miscarriages and spontaneous abortions of pregnancies among women directly exposed to these gases than among women not exposed. Most of the studies assessing exposure levels were conducted prior to the widespread use of scavenging systems. Air sampling was conducted in hospital operatories and recovery rooms of three large hospitals to assess the current exposure levels in these areas and determine the effectiveness of these systems in reducing exposures to fluoride-containing anesthetic gases. It was determined that recovery-room personnel are exposed to levels of anesthesia gases that often approach and exceed the recommended Threshold Limit Value-Time Weighted Average (TLV-TWA) of 2.0 ppm. Recovery-room personnel do not have the protection from exposure provided by scavenging systems in operating rooms. Operating-room personnel were exposed to anesthesia gas levels above the TLV-TWA only when patients were masked, or connected and disconnected from the scavenging systems. Recovery-room personnel also need to be protected from exposure to anesthesia gases by a scavenging system.

  5. THE UNIVERSITY OF CONNECTICUT HEALTH CENTER JOHN DEMPSEY HOSPITAL

    E-Print Network [OSTI]

    Oliver, Douglas L.

    plan for management of human resources reflects transition as deemed appropriate to the dynamic nature: MANAGEMENT OF HUMAN RESOURCES (STAFF RIGHTS) NUMBER: 10-030 SUBJECT: STAFF REQUESTS NOT TO PARTICIPATE PAGE: 1 of 3 PURPOSE: The John Dempsey Hospital plan for management of human resources is designed

  6. Does aluminum smelting cause lung disease

    SciTech Connect (OSTI)

    Abramson, M.J.; Wlodarczyk, J.H.; Saunders, N.A.; Hensley, M.J.

    1989-04-01T23:59:59.000Z

    The evidence concerning a relationship between work in the aluminum industry and lung disease has been reviewed using epidemiologic criteria. Adequate data on environmental exposure are rarely presented. Case series on aluminum potroom workers over the past 50 years have identified an asthmalike syndrome that appears to be due to an irritant rather than an allergic mechanism. These studies have been supported by evidence of within shift variability of measures of lung function. However, to date, there is inadequate evidence to resolve the question of whether potroom exposure initiates asthma or merely precipitates asthmalike symptoms in a predisposed individual. Cross-sectional studies have demonstrated evidence of reduced lung function, consistent with chronic airflow limitation. In exposed aluminum smelter workers compared to unexposed control subjects. Cigarette smoking, the major potential confounding variable, has been measured and accounted for in multivariate analyses. To date, evidence is lacking from longitudinal studies about the development of disabling chronic obstructive lung disease. Exposure to coal tar pitch volatiles in the production and consumption of anodes has biologic plausibility for an association of lung cancer with work in an aluminum smelter. Although retrospective mortality studies have failed to account for the probable high prevalence of smoking in blue collar workers, the relative risk of lung cancer is very low if present at all. Pulmonary fibrosis has not been shown to be a significant problem in aluminum smelter workers. Future research in the aluminum industry needs to concentrate on longitudinal studies, preferably with an inception cohort for the investigation of potroom asthma. 92 references.

  7. Real option analysis of flexibility in a hospital emergency department expansion project : a systems approach

    E-Print Network [OSTI]

    Maseda, Luis J

    2008-01-01T23:59:59.000Z

    Hospital Emergency Departments across the United States have been experiencing demand in excess of their capacity to treat patients for the last two decades. This research considers a hypothetical case inspired by a hospital ...

  8. A survey of access to trial of labor in California hospitals in 2012

    E-Print Network [OSTI]

    Barger, Mary K; Dunn, Jennifer Templeton; Bearman, Sage; DeLain, Megan; Gates, Elena

    2013-01-01T23:59:59.000Z

    of TOLAC hospitals had 24/7 anesthesia coverage and requiredavailable” and that anesthesia be available [5]. Then, in24-hour in-hospital anesthesia should also be available [6].

  9. Radiology of thoracic diseases

    SciTech Connect (OSTI)

    Swensen, S.J.; Pugatch, R.D.

    1989-01-01T23:59:59.000Z

    This book presents the essential clinical and radiologic findings of a wide variety of thoracic diseases. The authors include conventional, CT and MR images of each disease discussed. In addition, they present practical differential diagnostic considerations for most of the radiographic findings or patterns portrayed.

  10. Domestic violence is a health care problem of epidemic proportions. In addition to the immediate trauma caused by abuse, domestic violence contributes to a number of chronic health problems,

    E-Print Network [OSTI]

    Derisi, Joseph

    Domestic violence is a health care problem of epidemic proportions. In addition to the immediate trauma caused by abuse, domestic violence contributes to a number of chronic health problems, including depression, alcohol and substance abuse, sexually transmitted diseases such as HIV/AIDS, and often limits

  11. E-Print Network 3.0 - aarhus university hospital Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    STRATEGY AARHUS UNIVERSITY Summary: with aarhus university hospital about forensic medicine and health. the research-based advice to international......

  12. Evaluation of a surgical service in the chronic phase of a refugee camp: an example from the Thai-Myanmar border

    E-Print Network [OSTI]

    Weerasuriya, Chathika K; Tan, Saw O; Alexakis, Lykourgos C; Set, Aung K; Rijken, Marcus J; Martyn, Paul; Nosten, François; McGready, Rose

    2012-08-06T23:59:59.000Z

    -4] and reproductive health, the latter including female genital mutilation, refugee rights to abortion and family planning [5-9]. The focus is on the so called ‘emergent phase’ [10] of crisis situations which pertains to acute events (natural disaster, war, terrorist... and the majority of morbidity is associated with infectious and chronic diseases; while war trauma and reproductive health problems exist, these are comparatively minor. One of the principle health issues is multi-drug resis- tant Plasmodium falciparum malaria...

  13. Blue Shield ensures uninterrupted access to quality medical care after Palm Drive Hospital ceases operations

    E-Print Network [OSTI]

    Ravikumar, B.

    Blue Shield ensures uninterrupted access to quality medical care after Palm Drive Hospital ceases and inpatient services due to the hospital's bankruptcy filing. This closure affects Blue Shield HMO plan members who have been utilizing Palm Drive Hospital services. Please be advised that Blue Shield

  14. Colorado State University Veterinary Teaching Hospital Post Doc Fellow: Emergency & Critical Care Clinician

    E-Print Network [OSTI]

    Rutledge, Steven

    Colorado State University Veterinary Teaching Hospital Post Doc Fellow: Emergency & Critical Care Clinician Internal Search Only The Veterinary Teaching Hospital at Colorado State University is offering and critical care in a veterinary hospital setting. Applicant must be a current employee of Colorado State

  15. Nicotine patches and quitline counseling to help hospitalized smokers stay quit: Study protocol for a randomized controlled trial

    E-Print Network [OSTI]

    2012-01-01T23:59:59.000Z

    quitline services and NRT to help hospitalized smokers stayand quitline counseling to help hospitalized smokers stayfollow-up counseling can help prevent relapse. However, it

  16. Adventures in Infectious Diseases

    ScienceCinema (OSTI)

    Fisher-Hoch, Susan [University of Texas School of Public Health

    2014-06-25T23:59:59.000Z

    Dr. Susan Fisher-Hoch, Virologist and Epidemiologist, will discuss her research and travels associated with viral hemorrhagic fevers. From the Ebola outbreak in Reston, Virginia to outbreaks of Crimean Congo Hemorrhagic Fever in South Africa, Senegal, and Saudi Arabia, Dr. Fisher-Hoch has studied and tracked the pathophysiology of these viral diseases. These studies have led her from the Center for Disease Control in the United States, to Lyon, France where she was instrumental in designing, constructing, and rendering operational a laboratory capable of containing some of the world's most dangerous diseases.

  17. Impact of Hemodialysis on Lipid Profile among Chronic Renal Failure Patients- A Case Control Study

    E-Print Network [OSTI]

    unknown authors

    Abstract- Chronic Renal Failure (CRF) patients are at risk of cardiovascular diseases due to the elevation of various forms of lipids. Many a time CRF patients live on hemodialysis on regular basis. Present study was done to know whether hemodialysis has any impact on the lipid profile of the CRF patients. Study were divided into 3 groups, Group-I: healthy controls (30), Group-II: CRF patients who never undergone hemodialysis (30) and Group-III: CRF patients on hemodialysis for more than 6 months (30). We obtained serum samples from patients in the morning after an overnight fast and were analyzed for total cholesterol (TC), triglycerides (TGs), HDL, LDL and VLDL. Among the various parameters tested triglyceride and VLDL levels were significantly higher in group-II and III as compared to controls (p?0.01). HDL levels were significantly lower in group-II and III as compared to control (p?0.05). HDL level was found reduced in group-III as compared to Group-II (p?0.01). There was no significant change (p>0.05) observed in total cholesterol and LDL levels in between healthy controls and CRF patients with & without hemodialysis. There was no significant difference (p>0.05) observed between lipid profile in male and female patients in control group and in CRF patients with and without hemodialysis. It is concluded that both male and female patients of CRF with and without hemodialysis have characteristic dyslipidemias without any discrimination of sex and it is not attenuated by the hemodialysis process. Index Terms- Chronic renal failure, hemodialysis, lipid profile, cardiovascular diseases D

  18. Polish-American Children`s Hospital in Krakow, Poland. Project status report

    SciTech Connect (OSTI)

    Secrest, T.J.; Szydlowski, R.F. [Pacific Northwest Lab., Richland, WA (United States); Wade, D. [RDA Engineering, Inc., Marietta, GA (United States)

    1993-03-01T23:59:59.000Z

    In late 1990 staff from the US Department of Energy`s Office of Technical and Financial Assistance identified the Polish-American Children`s Hospital as a potential site for application of DOE expertise to reduce the Hospital`s energy requirements. Visits to the hospital in the fall and winter of 1991--1992 provided initial scoping of the energy related activities that would be supported by DOE. In addition to reducing energy requirements, the Hospital staff expressed a need for assistance in the areas of power quality and medical waste incineration. Subsequently, a power quality study supported by the Electric Power and Research Institute has been initiated and medical waste incineration will be provided by a Polish organization. The resulting scope of work for this effort is to survey the Hospital`s thermal energy supply and demand systems to identify no-cost and low-cost measures that will reduce the Hospital`s energy requirements. Applicable measures would then be demonstrated in the Hospital through a partnership with US and Polish organizations and a sister hospital in the United States.

  19. The Economy of Internet-Based Hospitality Exchange

    E-Print Network [OSTI]

    Tagiew, Rustam

    2015-01-01T23:59:59.000Z

    In this paper, we analyze and compare general development and individual behavior on two non-profit internet-based hospitality exchange services -- bewelcome.org and warmshowers.org. We measure the effort needed to achieve a real-life interaction, whereby the advantages of mutual altruism arise. The effort needed is the communication quantified in units of time. Since the amount of effort is not obvious to individual users, the development of the effort investing strategy is investigated. The impact of individual behavior on general development is discussed.

  20. Hospital Triage in First Hours After Nuclear or Radiological Disaster

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsruc DocumentationP-SeriesFlickr FlickrGuidedCH2MLLC HistoryVeterans | Updates andHospital Triage in

  1. Designing for Energy Conservation - The Cypress Fairbanks Medical Center Hospital

    E-Print Network [OSTI]

    Wiernik, L. B.; Ranzau, P. A.

    1984-01-01T23:59:59.000Z

    ,000 'quare foot is heat gain. The longest dbeneions of the Cypress cmprised Of three 40-bed medical'sur&ical In-patient Medical Center are oriented northwest and southeast. care nureing floors, and the first floor which houses All of the external windows... are 1/4" solar bronze administrative, business, dienostic, treatment and and internally ehded by 3" wide vertical blinds. ancillary services. The hospital is adjoined by a First floor windows are ehaded by a -$-foot overhang. 40,000 square foot med...

  2. Periodontal Disease and Heart Health

    E-Print Network [OSTI]

    Goldman, Steven A.

    Periodontal Disease and Heart Health Deaf HealthTalks Presenter: Christopher Lehfeldt, DDS Elmwood #12;X-ray showing bone loss rickwilsondmd.typepad.com Thursday, March 15, 12 #12;5. What is heart disease? · The medical name for heart disease is cardiovascular disease (CVD) · An American dies from CVD

  3. The association between depressive symptoms in the community, non-psychiatric hospital admission and hospital outcomes: a systematic review.

    E-Print Network [OSTI]

    Prina, A. Matthew; Cosco, Theodore D.; Dening, Tom; Beekman, Aartjan; Brayne, Carol; Huisman, Martijn

    2014-11-08T23:59:59.000Z

    E, Pagano F, Pozzi G, Bernabei R, Zuccala G. Depressive symptoms are associated with hospitalization, but not with mortality in the elderly: a population-based study. Aging Ment Health 2010;14:955–61. [24] Rowan PJ, Davidson K, Campbell JA, Dobrez DG... - sequent use of health and social services. Arch Gerontol Geriatr 2006;42: 125–39. [29] Brown JS, Boardman J, Whittinger N, Ashworth M. Can a self-referral system help improve access to psychological treatments? Br J Gen Pract 2010;60:365–71. [30] Wong SY...

  4. Large Hospital 50% Energy Savings: Technical Support Document

    SciTech Connect (OSTI)

    Bonnema, E.; Studer, D.; Parker, A.; Pless, S.; Torcellini, P.

    2010-09-01T23:59:59.000Z

    This Technical Support Document documents the technical analysis and design guidance for large hospitals to achieve whole-building energy savings of at least 50% over ANSI/ASHRAE/IESNA Standard 90.1-2004 and represents a step toward determining how to provide design guidance for aggressive energy savings targets. This report documents the modeling methods used to demonstrate that the design recommendations meet or exceed the 50% goal. EnergyPlus was used to model the predicted energy performance of the baseline and low-energy buildings to verify that 50% energy savings are achievable. Percent energy savings are based on a nominal minimally code-compliant building and whole-building, net site energy use intensity. The report defines architectural-program characteristics for typical large hospitals, thereby defining a prototype model; creates baseline energy models for each climate zone that are elaborations of the prototype models and are minimally compliant with Standard 90.1-2004; creates a list of energy design measures that can be applied to the prototype model to create low-energy models; uses industry feedback to strengthen inputs for baseline energy models and energy design measures; and simulates low-energy models for each climate zone to show that when the energy design measures are applied to the prototype model, 50% energy savings (or more) are achieved.

  5. Demonstration of Advanced Technologies for Multi-Load Washers in Hospitality and Healthcare – Wastewater Recycling Technology

    SciTech Connect (OSTI)

    Boyd, Brian K.; Parker, Graham B.; Petersen, Joseph M.; Sullivan, Greg; Goetzler, W.; Foley, K. J.; Sutherland, T. A.

    2014-08-14T23:59:59.000Z

    The objective of this demonstration project was to evaluate market-ready retrofit technologies for reducing the energy and water use of multi-load washers in healthcare and hospitality facilities. Specifically, this project evaluated laundry wastewater recycling technology in the hospitality sector and ozone laundry technology in both the healthcare and hospitality sectors. This report documents the demonstration of a wastewater recycling system installed in the Grand Hyatt Seattle.

  6. Health & Medicine Heart Disease

    E-Print Network [OSTI]

    Rogers, John A.

    See Also: Health & Medicine Heart Disease· Medical Imaging· Vioxx· Matter & Energy Electronics· Technology· Medical Technology· Reference Artificial heart· Biosensor· Circuit design· Machine· Science and stretchable electronics can map waves of electrical activity in the heart with better resolution and speed

  7. E-Print Network 3.0 - anesthesia department hospital Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    General Hospital... .m. Characterizing General Anesthesia- Induced Loss of Consciousness Jeff Shamma Warren M. Zapol Professor... , May 22 11:00 am 1146 AV Williams Bldg. Host...

  8. E-Print Network 3.0 - ayub teaching hospital Sample Search Results

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    10, 2005 Summary: of Tourism Research Asia Pacific Journal of Tourism Research ASEAN Journal on Hospitality and Tourism Current... of Ecotourism Journal of Quality...

  9. E-Print Network 3.0 - acute hospital wards Sample Search Results

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    42 UCSF Medical Center at Mission BayMission Bay Summary: ;UCSF Medical Center at Mission Bay - Recent milestonesRecent milestones Jan 2010: Submit hospital... 2010:...

  10. E-Print Network 3.0 - acute hospital care Sample Search Results

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Institute of Nursing Research (NINR) FOR IMMEDIATE Summary: -898-5074 Specialized Care from Hospital to Home Improves the Health of Elderly with Heart Failure, Cuts...

  11. ORISE: WeB-MEDIS System Allows Hospitals to Gather and Track...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    WeB-MEDIS ORISE-developed system helps emergency responders and hospitals gather and track patient data during emergencies The Oak Ridge Institute for Science and Education...

  12. Rebuilding it Better: Greensburg, Kansas, Kiowa County Memorial Hospital (Brochure) (Revised)

    Office of Energy Efficiency and Renewable Energy (EERE)

    This brochure details the sustainable and green aspects of the LEED Platinum-designed Kiowa County Memorial Hospital in Greensburg, Kansas.

  13. E-Print Network 3.0 - academic hospital perspective Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Vietnamese hospitals operate and put spotlight on input savings. Since the demand for health care is large Source: Feigon, Brooke - School of Mathematics, University of East...

  14. E-Print Network 3.0 - adolescent hospitalized Sample Search Results

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    FELLOW POSITION Department of Psychiatry Summary: at the Child and Adolescent Mental Health Care Program at Children's Hospital and will have desk space... POSTDOCTORAL FELLOW...

  15. E-Print Network 3.0 - analysis reduces hospital Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    29 ECPR General Conference, Potsdam, 10-12 September 2009 Panel: Rescaling Health Care Policy Summary: of influence in the hospital reform of post-soviet countries through...

  16. E-Print Network 3.0 - assiut university hospitals Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    14 College of Health Sciences Clinical Partners Dental Hygiene Summary: Mountain Health Care Tazewell County Health Department The Hospital of Extended Recovery University......

  17. E-Print Network 3.0 - abdulaziz university hospital Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    hospitals operate and put spotlight on input savings. Since the demand for health care is large Source: Feigon, Brooke - School of Mathematics, University of East...

  18. E-Print Network 3.0 - avoidable hospitalizations evidence Sample...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Open source software (OSS) has gained considerable attention recently in health care. Yet... , how and why OSS is being adopted within hospitals in particular remains a...

  19. E-Print Network 3.0 - ajou university hospital Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    hospitals operate and put spotlight on input savings. Since the demand for health care is large Source: Feigon, Brooke - School of Mathematics, University of East...

  20. E-Print Network 3.0 - aphm university hospital Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    hospitals operate and put spotlight on input savings. Since the demand for health care is large Source: Feigon, Brooke - School of Mathematics, University of East...

  1. E-Print Network 3.0 - atendidos num hospital Sample Search Results

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    , Sharma and Lozano 2000. A Vigilncia Epidemiolgica do Departamento de Medicina Social, do Hospital das Source: Baranauskas, Jos Augusto - Departamento de Fsica...

  2. adefovir-treated lamivudine-resistant chronic: Topics by E-print...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    pain of the lower back and neck. The focus of this work is on the multimodal input 37 Cough REVIEW Chronic cough hypersensitivity syndrome CiteSeer Summary: Chronic cough has...

  3. ANALYZING MUSCULAR PAIN AND THE EFFECTS OF EXERCISE ON CHRONIC PAIN

    E-Print Network [OSTI]

    Sharma, Neena

    2008-08-22T23:59:59.000Z

    Most people suffering from various chronic pain syndromes report deep tissue pain. However, our knowledge about chronic musculoskeletal pain is primarily based on rodent models of cutaneous pain. Little is known about ...

  4. Prevalence of Chronic Atrial Fibrillation in Dialysis Patients

    E-Print Network [OSTI]

    Wetmore, James B.

    2011-05-31T23:59:59.000Z

    .7) per 1000 patient-years. Age 60 years, male sex, Caucasian race, body mass index 30 kg/m2, and inability to ambulate were associated with chronic AF; hypertension as a comorbidity was inversely associated with AF. Occurrence of AF was roughly 10 times...

  5. Changes in Large Pulmonary Arterial Viscoelasticity in Chronic Pulmonary Hypertension

    E-Print Network [OSTI]

    Lakes, Roderic

    Changes in Large Pulmonary Arterial Viscoelasticity in Chronic Pulmonary Hypertension Zhijie Wang1 of pulmonary arterial hypertension (PAH) and is an excellent predictor of mortality due to right ventricular at a physiologically relevant frequency (10 Hz) in hypertensive PAs. The dynamic elastic modulus (E), a material

  6. Activated ClpP kills persisters and eradicates a chronic biofilm infection.

    SciTech Connect (OSTI)

    Conlon, Brian P.; Nakayasu, Ernesto S.; Fleck, Laura E.; LaFleur, Michael D.; Isabella, Vincent M.; Coleman, K.; Leonard, Steve N.; Smith, Richard D.; Adkins, Joshua N.; Lewis, Kim

    2013-11-21T23:59:59.000Z

    The current antibiotic crisis stems from two distinct phenomena-drug resistance, and drug tolerance. Resistance mechanisms such as drug efflux or modification prevent antibiotics from binding to their targets 1, allowing pathogens to grow. Antibiotic tolerance is the property of persister cells, phenotypic variants of regular bacteria 2. Antibiotics kill by corrupting targets, but these are inactive in dormant persisters, leading to tolerance. Persisters were first identified by Joseph Bigger in 1944, when he discovered a surviving sub-population of Staphylococcus following treatment with penicillin3. Persisters are largely responsible for recalcitrance of chronic diseases such as tuberculosis, and various infections associated with biofilms - endocarditis, osteomyelitis, infections of catheters and indwelling devices, and deep-seated infections of soft tissues 4. There are a number of redundant pathways involved in persister formation5,6 precluding development of drugs inhibiting their formation. The acyldepsipeptide antibiotic (ADEP 4) has been shown to activate the ClpP protease resulting in death of growing cells 7. Here we show that ADEP4 activated ClpP becomes a fairly non-specific protease and kills persister cells by degradation of over 400 intracellular targets. clpP mutants are resistant to ADEP4 7, but we find that they display increased susceptibility to killing by a range of conventional antibiotics. Combining ADEP4 with rifampicin leads to eradication of persisters, stationary and biofilm populations of Staphylococcus aureus in vitro and in a deep-seated murine infection. Target corruption/activation provides an approach to killing persisters and eradicating chronic infections.

  7. Effect of chronic inhalation of inorganic arsenic on the risk of stillbirth in a community surrounding an agriculture chemical production facility: a hospital-based study

    E-Print Network [OSTI]

    Ihrig, Melanie M

    1997-01-01T23:59:59.000Z

    series of epidemiological studies were carried out in a community surrounding a copper smelter in Ronnskar, Sweden, where arsenic was considered a major environmental pollutant. The frequency of spontaneous abortion was increased among women living... in the community nearest the smelter relative to the frequency in women living in similar communities located farther from the smelter (10). Furthermore, the birthweight of infants born to women living nearest the smelter were lower compared with those...

  8. Chobert MN et al LIVER PRECURSOR CELLS INCREASE HEPATIC FIBROSIS INDUCED BY CHRONIC

    E-Print Network [OSTI]

    Boyer, Edmond

    by chronic carbon tetrachloride (CCl4) administration for 6 weeks, in combination with chronic; CCl4, carbon tetrachloride; CK19, cytokeratin 19; CCR2, chemokine C-C motif receptor 2; EMTChobert MN et al LIVER PRECURSOR CELLS INCREASE HEPATIC FIBROSIS INDUCED BY CHRONIC CARBON

  9. Asbestos-related pulmonary disease in boilermakers

    SciTech Connect (OSTI)

    Demers, R.Y.; Neale, A.V.; Robins, T.; Herman, S.C. (Wayne State Univ., Detroit, MI (USA))

    1990-01-01T23:59:59.000Z

    Boilermakers are skilled building tradesmen who construct, repair, and dismantle boilers. The present study reports on the evaluation of members of a Michigan boilermaker's union for the presence of signs and symptoms of chronic pulmonary disease. Study variables included standardized evaluations of chest x-ray findings, pulmonary function testing, physical examination, and respiratory symptoms. An overall participation rate of 69% was achieved. A non-participant survey identified no significant differences between participants and non-participants in dyspnea, cough, age, or smoking history. Among participants with greater than 20 years experience in the trade, the mean FVC was 91% of predicted; the FEV1 was 86% of predicted; 25% showed at least a 1/0 profusion of interstitial markings on chest x-ray; 30% had bilateral pleural abnormalities; and 52% had audible inspiratory rales on physical examination. Forced vital capacity and forced expiratory volume at one second both decreased with years in the trade. Chest x-ray findings of interstitial fibrosis and pleural plaques were related to ten or more years in the trade, as were respiratory symptoms of pulmonary rales, wheeze, and dyspnea.

  10. Inherited risk for common disease

    E-Print Network [OSTI]

    Banava, Helen

    2007-01-01T23:59:59.000Z

    Linkage disequilibrium studies have discovered few gene-disease associations for common diseases. The explanation has been offered that complex modes of inheritance govern risk for cancers, cardiovascular and cerebrovascular ...

  11. DOES HOSPITAL COMPETITION SAVE LIVES? EVIDENCE FROM THE ENGLISH NHS PATIENT CHOICE REFORMS*

    E-Print Network [OSTI]

    Mateo, Jill M.

    DOES HOSPITAL COMPETITION SAVE LIVES? EVIDENCE FROM THE ENGLISH NHS PATIENT CHOICE REFORMS* Zack Cooper, Stephen Gibbons, Simon Jones and Alistair McGuire Recent substantive reforms to the English with fixed prices. This study investigates whether these reforms led to improvements in hospital quality. We

  12. LeBonheur Children's Hospital/Aesthetic Surgery Plastic Surgery Rotation

    E-Print Network [OSTI]

    Cui, Yan

    LeBonheur Children's Hospital/Aesthetic Surgery Plastic Surgery Rotation PGY-7 (2nd year Resident) By the end of the Plastic Surgery Rotation at LeBonheur Children's Hospital and Aesthetic Surgery, the PGY-7 with the following conditions needing plastic surgery including but not limited to: · Mammary ptosis. mammary

  13. A Hierarchical Bayesian Model for Improving Short-Term Forecasting of Hospital Demand by Including Meteorological

    E-Print Network [OSTI]

    Sahu, Sujit K

    A Hierarchical Bayesian Model for Improving Short-Term Forecasting of Hospital Demand by Including Sarran4 Abstract The effect of weather on health has been widely researched, and the ability to forecast, better predictions of hospital demand that are more sensitive to fluctuations in weather can allow

  14. Investigation of PVC Pipe Failure at Terrell State Hospital – Final Report

    E-Print Network [OSTI]

    Wei, G.; Deng, S.; Claridge, D. E.; Turner, W. D.

    2000-01-01T23:59:59.000Z

    At the request of Terrell State Hospital and MHMR, the Energy Systems Laboratory at Texas A&M University investigated the failure of the PVC pipes serving the chilled water loop at Terrell State Hospital. There were two PVC pipe failures where...

  15. Students in Health Sciences at the UA simulate real hospital practice with the latest technological devices

    E-Print Network [OSTI]

    Escolano, Francisco

    , as well as maternal and child care. It is equipped with hospital beds, incubators, medical simulationStudents in Health Sciences at the UA simulate real hospital practice with the latest technological that will allow students to complete their practical training with the latest technological devices. The opening

  16. Technical Support Document: Development of the Advanced Energy Design Guide for Large Hospitals - 50% Energy Savings

    SciTech Connect (OSTI)

    Bonnema, E.; Leach, M.; Pless, S.

    2013-06-01T23:59:59.000Z

    This Technical Support Document describes the process and methodology for the development of the Advanced Energy Design Guide for Large Hospitals: Achieving 50% Energy Savings Toward a Net Zero Energy Building (AEDG-LH) ASHRAE et al. (2011b). The AEDG-LH is intended to provide recommendations for achieving 50% whole-building energy savings in large hospitals over levels achieved by following Standard 90.1-2004. The AEDG-LH was created for a 'standard' mid- to large-size hospital, typically at least 100,000 ft2, but the strategies apply to all sizes and classifications of new construction hospital buildings. Its primary focus is new construction, but recommendations may be applicable to facilities undergoing total renovation, and in part to many other hospital renovation, addition, remodeling, and modernization projects (including changes to one or more systems in existing buildings).

  17. Quality assurance of HDR prostate plans: Program implementation at a community hospital

    SciTech Connect (OSTI)

    Rush, Jennifer B. [Department of Radiation Oncology, High Point Regional Hospital, High Point, NC (United States); Thomas, Michael D. [Department of Radiation Oncology, High Point Regional Hospital, High Point, NC (United States)]. E-mail: mthomas@hprhs.com

    2005-01-01T23:59:59.000Z

    Adenocarcinoma of the prostate is currently the most commonly diagnosed cancer in men in the United States, and the second leading cause of cancer mortality. The utilization of radiation therapy is regarded as the definitive local therapy of choice for intermediate- and high-risk disease, in which there is increased risk for extracapsular extension, seminal vesicle invasion, or regional node involvement. High-dose-rate (HDR) brachytherapy is a logical treatment modality to deliver the boost dose to an external beam radiation therapy (EBRT) treatment to increase local control rates. From a treatment perspective, the utilization of a complicated treatment delivery system, the compressed time frame in which the procedure is performed, and the small number of large dose fractions make the implementation of a comprehensive quality assurance (QA) program imperative. One aspect of this program is the QA of the HDR treatment plan. Review of regulatory and medical physics professional publications shows that substantial general guidance is available. We provide some insight to the implementation of an HDR prostate plan program at a community hospital. One aspect addressed is the utilization of the low-dose-rate (LDR) planning system and the use of existing ultrasound image sets to familiarize the radiation therapy team with respect to acceptable HDR implant geometries. Additionally, the use of the LDR treatment planning system provided a means to prospectively determine the relationship between the treated isodose volume and the product of activity and time for the department's planning protocol prior to the first HDR implant. For the first 12 HDR prostate implants, the root-mean-square (RMS) deviation was 3.05% between the predicted product of activity and time vs. the actual plan values. Retrospective re-evaluation of the actual implant data reduced the RMS deviation to 2.36%.

  18. New therapeutic aspect for carvedilol: Antifibrotic effects of carvedilol in chronic carbon tetrachloride-induced liver damage

    SciTech Connect (OSTI)

    Hamdy, Nadia [Department of Biochemistry, Faculty of Pharmacy, Ain Shams University, Cairo (Egypt)] [Department of Biochemistry, Faculty of Pharmacy, Ain Shams University, Cairo (Egypt); El-Demerdash, Ebtehal, E-mail: ebtehal_dm@yahoo.com [Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University, Cairo (Egypt)] [Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University, Cairo (Egypt)

    2012-06-15T23:59:59.000Z

    Portal hypertension is a common complication of chronic liver diseases associated with liver fibrosis and cirrhosis. At present, beta-blockers such as carvedilol remain the medical treatment of choice for protection against variceal bleeding and other complications. Since carvedilol has powerful antioxidant properties we assessed the potential antifibrotic effects of carvedilol and the underlying mechanisms that may add further benefits for its clinical usefulness using a chronic model of carbon tetrachloride (CCl4)-induced hepatotoxicity. Two weeks after CCl4 induction of chronic hepatotoxicity, rats were co-treated with carvedilol (10 mg/kg, orally) daily for 6 weeks. It was found that treatment of animals with carvedilol significantly counteracted the changes in liver function and histopathological lesions induced by CCl4. Also, carvedilol significantly counteracted lipid peroxidation, GSH depletion, and reduction in antioxidant enzyme activities; glutathione-S-transferase and catalase that was induced by CCl4. In addition, carvedilol ameliorated the inflammation induced by CCl4 as indicated by reducing the serum level of acute phase protein marker; alpha-2-macroglobulin and the liver expression of nuclear factor-kappa B (NF-?B). Finally, carvedilol significantly reduced liver fibrosis markers including hydroxyproline, collagen accumulation, and the expression of the hepatic stellate cell (HSC) activation marker; alpha smooth muscle actin. In conclusion, the present study provides evidences for the promising antifibrotic effects of carvedilol that can be explained by amelioration of oxidative stress through mainly, replenishment of GSH, restoration of antioxidant enzyme activities and reduction of lipid peroxides as well as amelioration of inflammation and fibrosis by decreasing collagen accumulation, acute phase protein level, NF-?B expression and finally HSC activation. -- Highlights: ? Carvedilol is a beta blocker with antioxidant and antifibrotic properties. ? It restores GSH and antioxidant enzyme activities and reduces lipid peroxidation. ? It ameliorates inflammation and nuclear factor kappa-B expression. ? It ameliorates fibrosis by decreasing collagen accumulation and HSC activation.

  19. active chronic lymphocytic: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    cause diseases with long incubation periods, insidious onsets, and slowly progressive courses (1). The members of the virus group include visna virus of sheep, caprine...

  20. Sulfur dioxide-induced chronic bronchitis in beagle dogs

    SciTech Connect (OSTI)

    Greene, S.A.; Wolff, R.K.; Hahn, F.F.; Henderson, R.F.; Mauderly, J.L.; Lundgren, D.L.

    1984-01-01T23:59:59.000Z

    This study was done to produce a model of chronic bronchitis. Twelve beagle dogs were exposed to 500 ppm sulfur dioxide (SO/sub 2/) for 2 h/d, 5d/wk for 21 wk and 4 dogs were sham-exposed to filtered ambient air for the same period. Exposure effects were evaluated by periodically examining the dogs using chest radiographs, pulmonary function, tracheal mucous clearance, and the cellular and soluble components of bronchopulmonary lavage fluids. Dogs were serially sacrificed after 13 and 21 wk of exposure and after 6 and 14 wk of recovery. Clinical signs produced in the SO/sub 2/-exposed dogs included mucoid nasal discharge, productive cough, moist rales on auscultation, tonsilitis, and conjunctivitis. Chest radiographs revealed mild peribronchiolar thickening. Histopathology, tracheal mucous clearance measurements, and lavage cytology were consistent with a diagnosis of chronic bronchitis. It is concluded that repeated exposure to 500 ppm SO/sub 2/ for 21 wk produced chronic bronchitis in the beagle dog. Complete recovery occurred within 5 wk following cessation of SO/sub 2/ exposure. 43 references, 2 figures, 2 tables.

  1. Mathematical model of gas plasma applied to chronic wounds

    SciTech Connect (OSTI)

    Wang, J. G.; Liu, X. Y.; Liu, D. W.; Lu, X. P. [State Key Lab of Advanced Electromagnetic Engineering and Technology, Huazhong University of Science and Technology, WuHan, HuBei 430074 (China)] [State Key Lab of Advanced Electromagnetic Engineering and Technology, Huazhong University of Science and Technology, WuHan, HuBei 430074 (China); Zhang, Y. T. [Shandong Provincial Key Lab of UHV Technology and Gas Discharge Physics, School of Electrical Engineering, Shandong University, Jinan, Shandong Province 250061 (China)] [Shandong Provincial Key Lab of UHV Technology and Gas Discharge Physics, School of Electrical Engineering, Shandong University, Jinan, Shandong Province 250061 (China)

    2013-11-15T23:59:59.000Z

    Chronic wounds are a major burden for worldwide health care systems, and patients suffer pain and discomfort from this type of wound. Recently gas plasmas have been shown to safely speed chronic wounds healing. In this paper, we develop a deterministic mathematical model formulated by eight-species reaction-diffusion equations, and use it to analyze the plasma treatment process. The model follows spatial and temporal concentration within the wound of oxygen, chemoattractants, capillary sprouts, blood vessels, fibroblasts, extracellular matrix material, nitric oxide (NO), and inflammatory cell. Two effects of plasma, increasing NO concentration and reducing bacteria load, are considered in this model. The plasma treatment decreases the complete healing time from 25 days (normal wound healing) to 17 days, and the contributions of increasing NO concentration and reducing bacteria load are about 1/4 and 3/4, respectively. Increasing plasma treatment frequency from twice to three times per day accelerates healing process. Finally, the response of chronic wounds of different etiologies to treatment with gas plasmas is analyzed.

  2. Third Report of the California Hospital Outcomes Project (1997): Report on Heart Attack, 1991-1993 Volume 3

    E-Print Network [OSTI]

    Romano, Patrick S; Luft, Harold S; Rainwater, Julie A

    1997-01-01T23:59:59.000Z

    18 N O P Q Report on Heart Attack Hospital Detailed Results,18 N O P Q Report on Heart Attack Hospital Detailed Results,HS, Romano PS. Report on Heart Attack, 1991-1993, Volume 3:

  3. Contrast Set Mining for Distinguishing between Similar Diseases

    E-Print Network [OSTI]

    Novak, Petra Kralj

    , 10000 Zagreb, Croatia 4 University Hospital of Traumatology, Draskovi´ceva 19, 10000 Zagreb, Croatia

  4. A Manual of Poultry Diseases.

    E-Print Network [OSTI]

    Bell, R. R.; Flowers, A. I.; Grumbles, L. C.; Meinecke, C. F.; Patterson, C. M.; Wormell, B. C.; Hall, C. F.

    1965-01-01T23:59:59.000Z

    " of ocular leucosis is specific. Hatchery and Breeder Flock Health Management Sanitation is a much used, but poorly defined word. The usual implication is that sanitation is a universally understood practice that may be applied to prevent all diseases... must be based on the nature of specific diseases. The ;kmbiguity surrounding the term "sanitation" can be avoided by using a term "management and sanitation for disease prevention." This phrase then would be defined as all practices, specific...

  5. Causal Inference and Prediction in Health Studies: Environmental Exposures and Schistosomiasis, HIV-1 Genotypic Susceptibility Scores and Virologic Suppression, and Risk of Hospital Readmission for Heart Failure Patients

    E-Print Network [OSTI]

    Sudat, Sylvia

    2012-01-01T23:59:59.000Z

    hospitalization for congestive heart failure among Medicarepredictors of readmission for heart failure: a systematicof hospital readmission for heart failure: development of a

  6. Pre-Hospital Practices for Handling a Radiologically Contaminated Patient |

    Office of Environmental Management (EM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "of EnergyEnergyENERGY TAXBalanced ScorecardReactorBatteriesDiseaseDOE SmallQuadrennialN E RDepartment of

  7. Repetitive Pediatric Anesthesia in a Non-Hospital Setting

    SciTech Connect (OSTI)

    Buchsbaum, Jeffrey C., E-mail: jbuchsba@iupui.edu [Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, Indiana (United States); Indiana University Health Proton Therapy Center, Bloomington, Indiana (United States); McMullen, Kevin P.; Douglas, James G. [Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, Indiana (United States) [Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, Indiana (United States); Indiana University Health Proton Therapy Center, Bloomington, Indiana (United States); Jackson, Jeffrey L.; Simoneaux, R. Victor; Hines, Matthew; Bratton, Jennifer; Kerstiens, John [Indiana University Health Proton Therapy Center, Bloomington, Indiana (United States)] [Indiana University Health Proton Therapy Center, Bloomington, Indiana (United States); Johnstone, Peter A.S. [Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, Indiana (United States) [Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, Indiana (United States); Indiana University Health Proton Therapy Center, Bloomington, Indiana (United States)

    2013-04-01T23:59:59.000Z

    Purpose: Repetitive sedation/anesthesia (S/A) for children receiving fractionated radiation therapy requires induction and recovery daily for several weeks. In the vast majority of cases, this is accomplished in an academic center with direct access to pediatric faculty and facilities in case of an emergency. Proton radiation therapy centers are more frequently free-standing facilities at some distance from specialized pediatric care. This poses a potential dilemma in the case of children requiring anesthesia. Methods and Materials: The records of the Indiana University Health Proton Therapy Center were reviewed for patients requiring anesthesia during proton beam therapy (PBT) between June 1, 2008, and April 12, 2012. Results: A total of 138 children received daily anesthesia during this period. A median of 30 fractions (range, 1-49) was delivered over a median of 43 days (range, 1-74) for a total of 4045 sedation/anesthesia procedures. Three events (0.0074%) occurred, 1 fall from a gurney during anesthesia recovery and 2 aspiration events requiring emergency department evaluation. All 3 children did well. One aspiration patient needed admission to the hospital and mechanical ventilation support. The other patient returned the next day for treatment without issue. The patient who fell was not injured. No patient required cessation of therapy. Conclusions: This is the largest reported series of repetitive pediatric anesthesia in radiation therapy, and the only available data from the proton environment. Strict adherence to rigorous protocols and a well-trained team can safely deliver daily sedation/anesthesia in free-standing proton centers.

  8. Enthalpy Wheels Come of Age: Applying Energy Recovery Ventilation to Hospitality Venues in Hot, Humid Climate

    E-Print Network [OSTI]

    Wellford, B. W.

    2000-01-01T23:59:59.000Z

    ventilation to hospitality venues in hot, humid climates need not be complex. This paper proposes guidelines that can facilitate application of the technology by specifiers or other construction professionals. These guidelines address evaluation of typical...

  9. In sickness and in wealth : hospitals, community benefits, and the Affordable Care Act

    E-Print Network [OSTI]

    Mella, Katherine M. (Katherine Manuela)

    2014-01-01T23:59:59.000Z

    The new community benefit guidelines for non-profit hospitals enacted by the 2010 Patient Protection and Affordable Care Act (ACA) present major opportunities for the public health and planning fields alike. Given that ...

  10. Energy Conservation Recommendations, Implementation Costs, and Projected Paybacks for Georgia's Targeted Schools and Hospitals Conservation Program

    E-Print Network [OSTI]

    Brown, M. L.; Moore, D. M.

    1988-01-01T23:59:59.000Z

    During the past year the Georgia Tech Research Institute performed technical assistance studies on over 100 school and hospital buildings under a program funded by the Governor's Office of Energy Resources. This program is known as the Targeted...

  11. Exploration of the Practices of Credentialing of Nurse Practitioners in Acute Care Hospital Settings

    E-Print Network [OSTI]

    Hronek, Carla M.

    2014-05-31T23:59:59.000Z

    Abstract The nursing shortage, physician shortage, advancing age of the population, and concerns about equalizing access to health care have supported the movement of the Nurse Practitioner (NP) role into the acute care hospital setting (ACHS...

  12. Nonprofit Hospitals’ Approach to Community Health Needs Assessment: A Mixed Methods Study

    E-Print Network [OSTI]

    Pennel, Cara LeAnne

    2014-07-15T23:59:59.000Z

    Nonprofit hospitals are tax exempt but must demonstrate community benefit to the Internal Revenue Service (IRS) to maintain this status. In attempts to improve accountability, the Patient Protection and Affordable Care Act of 2010 includes a...

  13. System transferability of public hospital facility management between Germany and Iran.

    E-Print Network [OSTI]

    Banedj-Schafii, Mandana

    2009-01-01T23:59:59.000Z

    ??The subject of this PhD-thesis is the transferability of Facility Management (FM) by using the example of hospitals in Germany and Iran. The intention is… (more)

  14. Managing variability to improve quality, capacity and cost in the perioperative process at Massachusetts General Hospital

    E-Print Network [OSTI]

    Price, Devon J. (Devon Jameson)

    2011-01-01T23:59:59.000Z

    The widely held assumption is that to improve access and quality of health care, we need to spend more. In fact, that is not necessarily true. The results of this project, performed at Massachusetts General Hospital (MGH), ...

  15. E-Print Network 3.0 - al hospital rural Sample Search Results

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    search results for: al hospital rural Page: << < 1 2 3 4 5 > >> 1 RESPONDING TO RURAL HEALTH DISPARITIES IN THE UNITED STATES: THE GEOGRAPHY OF EMERGENCY CARE AND TELEMEDICAL...

  16. A plan for Metropolitan State Hospital : imagery as a therapy for an institution

    E-Print Network [OSTI]

    McMurrin, Sterling James

    1988-01-01T23:59:59.000Z

    This thesis is both text and illustration to describe the process of transforming a state mental institution from an outdated, outmoded, conventional hospital into a living community. The goal of the project is to develop ...

  17. THE IMPACT OF WORK UNIT AND ORGANIZATION SUPPORT ON HOSPITAL PATIENT SAFETY

    E-Print Network [OSTI]

    Kemper, Carol Ann

    2009-01-27T23:59:59.000Z

    Based on the construct of a culture of safety, the study purpose was to discern the relationships between Organization Support (OS) and Work Unit Support (WS) on Hospital Patient Safety. OS and WS were operationalized ...

  18. NREL Technical Reports Guide the Way to 50% Energy Savings in Hospitals, Office Buildings (Fact Sheet)

    SciTech Connect (OSTI)

    Not Available

    2011-02-01T23:59:59.000Z

    Researchers at the National Renewable Energy Laboratory (NREL) have developed two technical reports that provide recommendations to help designers and operators of large office buildings and hospitals achieve at least a 50% energy savings using existing technology.

  19. Continuous Commissioning of the Reynolds Army Community Hospital, Fort Sill, Oklahoma

    E-Print Network [OSTI]

    Turner, W. D.; Baltazar-Cervantes, J. C.; Martinez, J. T.

    2007-01-01T23:59:59.000Z

    ) during both phases of the project. In this paper the optimization of the facilities Heating, Ventilation, and Air Conditioning (HVAC) systems through the CC® process is presented. Detailed commissioning activities of the Hospital and Central Plant...

  20. Development of design strategies to support evacuation process of hospital buildings in united states

    E-Print Network [OSTI]

    Kader, Sharmin

    2009-05-15T23:59:59.000Z

    a serious consideration has also been given to terrorist incidents and hazardous material spills (Taaffe et al., 2005). In general, a hospital is a place of immediate care for a large number of people during emergencies (FEMA, 2007). But sometimes... point depending on the size of the building (Lewis et al, 2003, Drabek, 1999, Vogt et al, 1990, and NYTCP, 2006, and Burgun, 1994). e) Emergency Operation System Hospital must have emergency electrical services. Emergency power shall be provided...

  1. E-Print Network 3.0 - adult chronic immune Sample Search Results

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    however, immunity wanes with age... present as a mild, but chronic infectious cough. It's when an infected adult unsuspectingly infects... the vaccine was offered. This...

  2. E-Print Network 3.0 - attenuates chronic cigarette Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Fever Muscle Aches Ears: Ache Itch Hearing loss Ringing Drainage Stuffiness Summary: : Cough Phlegm Short of breath Pain Have you ever had? Chronic illness Mono Asthma...

  3. E-Print Network 3.0 - advanced chronic obstructive Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Bronchiectasis Summary: sev- eral clinical features with COPD, including chronic cough, airflow obstruction, lower airway... with declining lung function and advanced...

  4. aav-mediated chronic over-expression: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    obstructive uropathy.Autonomic neuropathy is well associated with chronic renal failure patients. Knowledge of autonomic dysfunction canencourage patients and physicians to...

  5. Chronic instability of the anterior syndesmosis of the ankle: Biomechanical, kinematical, radiological and clinical aspects.

    E-Print Network [OSTI]

    A. Beumer (Annechien)

    2007-01-01T23:59:59.000Z

    ??abstractThis thesis is concerned with chronic anterior instability of the tibiofibular syndesmosis of the ankle. The ankle plays a fundamental role in locomotion. It consists… (more)

  6. E-Print Network 3.0 - adolescent illness chronic Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Email Address: dmf21@psu.edu Research Interests... ; provider-family interaction in health care encounters; chronic conditions among children and adolescents... Address:...

  7. E-Print Network 3.0 - aids chronic infection Sample Search Results

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Summary: by vaccination should exceed levels in chronic infection for protection from HIV Hester Korthals Altesa,, David A... response should be boosted to levels exceeding those...

  8. Activation of farnesoid X receptor attenuates hepatic injury in a murine model of alcoholic liver disease

    SciTech Connect (OSTI)

    Wu, Weibin [Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai 200032 (China) [Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai 200032 (China); Institutes of Biomedical Science, Fudan University, Shanghai 200032 (China); Zhu, Bo; Peng, Xiaomin [Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai 200032 (China)] [Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai 200032 (China); Zhou, Meiling, E-mail: meilingzhou2012@gmail.com [Department of Radiology, Zhongshan Hospital of Fudan University and Shanghai Institute of Medical Imaging, Shanghai 200032 (China)] [Department of Radiology, Zhongshan Hospital of Fudan University and Shanghai Institute of Medical Imaging, Shanghai 200032 (China); Jia, Dongwei, E-mail: jiadongwei@fudan.edu.cn [Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai 200032 (China)] [Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai 200032 (China); Gu, Jianxin [Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai 200032 (China) [Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai 200032 (China); Institutes of Biomedical Science, Fudan University, Shanghai 200032 (China)

    2014-01-03T23:59:59.000Z

    Highlights: •FXR activity was impaired by chronic ethanol ingestion in a murine model of ALD. •Activation of FXR attenuated alcohol-induced liver injury and steatosis. •Activation of FXR attenuated cholestasis and oxidative stress in mouse liver. -- Abstract: Alcoholic liver disease (ALD) is a common cause of advanced liver disease, and considered as a major risk factor of morbidity and mortality worldwide. Hepatic cholestasis is a pathophysiological feature observed in all stages of ALD. The farnesoid X receptor (FXR) is a member of the nuclear hormone receptor superfamily, and plays an essential role in the regulation of bile acid, lipid and glucose homeostasis. However, the role of FXR in the pathogenesis and progression of ALD remains largely unknown. Mice were fed Lieber-DeCarli ethanol diet or an isocaloric control diet. We used a specific agonist of FXR WAY-362450 to study the effect of pharmacological activation of FXR in alcoholic liver disease. In this study, we demonstrated that FXR activity was impaired by chronic ethanol ingestion in a murine model of ALD. Activation of FXR by specific agonist WAY-362450 protected mice from the development of ALD. We also found that WAY-362450 treatment rescued FXR activity, suppressed ethanol-induced Cyp2e1 up-regulation and attenuated oxidative stress in liver. Our results highlight a key role of FXR in the modulation of ALD development, and propose specific FXR agonists for the treatment of ALD patients.

  9. A CENSUS OF LONG STAY PATIENTS IN GOVERNMENT MENTAL HOSPITALS IN INDIA

    E-Print Network [OSTI]

    M. Venkataswamy Reddy

    A single day census found that long-stay patients (LSP) numbering 7,307 accounted for about 48 % of the total inpatient strength of 15,345 in government mental hospitals in India. A load of 2695 (37%) LSP were in two to five years duration of stay, 2782 (38%) were in five to fifteen years duration of stay, and the remaining 1830 (25%) were staying for more than fifteen years. About 11 % of LSP were aged sixty years and above, majority (53%) were males, non-voluntary cases constituted 80%. and more than two-thirds (69%) were schizophrenics. The characteristics distributions associated with high rates of LSP at individual hospitals were identified. The load of LSP was decreased by 9 % during the period from 1993 to 1999. Key words: Census, long-stay patients, government mental hospitals, national indicators Sufficient data on long-stay patients (LSP) in government mental hospitals were lacking in India, though certain informations about some individual hospitals or a small group of hospitals have been reported (Sathyavathi and

  10. MFR PAPER 1300 Shellfish Diseases

    E-Print Network [OSTI]

    promise for the efficient recycling of organic waste materials, such as agricultural wastes, and metazoan parasitic and infectious agents. In addition, predators, toxic agents, and fouling organisms studied. DISEASES OF SHELLFISH A list of organisms that cause com- mon diseases in oysters is shown

  11. Short-term effects of air pollution: a panel study of blood markers in patients with chronic pulmonary disease

    E-Print Network [OSTI]

    2009-01-01T23:59:59.000Z

    monoxide [NO], nitrogen dioxide [NO 2 ], carbon monoxide [monoxide (NO), nitrogen dioxide (NO 2 ), carbon monoxide (dioxide; NO 2 , nitrogen dioxide; CO, carbon monoxide; NO,

  12. Examining Public Health System Responses to the Chronic Diseases of HIV/AIDS and Diabetes: Experiences from Mexico and Brazil

    E-Print Network [OSTI]

    Gidi, Virginia Eve

    2010-01-01T23:59:59.000Z

    of its own design. The pharmaceutical industry sponsors someARVs with the pharmaceutical industry, resulting in vastlyfrom the pharmaceutical industry who are interested in

  13. Examining Public Health System Responses to the Chronic Diseases of HIV/AIDS and Diabetes: Experiences from Mexico and Brazil

    E-Print Network [OSTI]

    Gidi, Virginia Eve

    2010-01-01T23:59:59.000Z

    da Saude: Brasilia. Ministerio da Saúde do Brasil,Saude Brasil 2008: 20 anos de sistemaunico de saude (SUS) no Brasil, Secretaria de Vigiliancia en

  14. Examining Public Health System Responses to the Chronic Diseases of HIV/AIDS and Diabetes: Experiences from Mexico and Brazil

    E-Print Network [OSTI]

    Gidi, Virginia Eve

    2010-01-01T23:59:59.000Z

    generations of reform in Mexico. Lancet, 2003. 362(9396): p.Carillo, and J.J. García, Mexico, in World Health Systems:Secretaria de Salud de Mexico and et al, Numeralia 2008:

  15. Predicting Wrist Movement Trajectory from Ipsilesional ECoG in Chronic Stroke Patients

    E-Print Network [OSTI]

    Grust, Torsten

    Predicting Wrist Movement Trajectory from Ipsilesional ECoG in Chronic Stroke Patients Martin Sp (BCI), Brain-Machine Interface (BMI), Stroke, Trajectory Prediction, Electrocor- ticography (ECo a Brain-Computer Interface (BCI) for chronic stroke patients. The prediction of movement trajectory based

  16. ORIGINAL ARTICLE An in vitro model for the growth and analysis of chronic

    E-Print Network [OSTI]

    Parker, Albert E.

    ORIGINAL ARTICLE An in vitro model for the growth and analysis of chronic wound MRSA biofilms A, biofilms, chronic wounds, in vitro model, MRSA. Correspondence Alessandra M. Agostinho, Center for Biofilm) for the growth and analysis of methicillin-resistant Staphylococcus aureus (MRSA) biofilms. Methods and Results

  17. Eur Heart J . Author manuscript Chronic heart rate reduction with ivabradine improves systolic function of

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Eur Heart J . Author manuscript Page /1 11 Chronic heart rate reduction with ivabradine improves systolic function of the reperfused heart through a dual mechanism involving a direct mechanical effect the adaptations of left ventricular function and calcium handling to chronic heart rate reduction with ivabradine

  18. Age, gender, and breed as risk factors for acute and chronic equine laminitis

    E-Print Network [OSTI]

    Alford, Patricia Lee

    1999-01-01T23:59:59.000Z

    , and time of diagnosis. The 90% of case-control pairs (78 acute, 155 chronic) having complete data for age, gender, and breed were used in separate conditional logistic recession models for acute and chronic laminitis. The odds ratio was calculated...

  19. Lab Invest . Author manuscript Liver precursor cells increase hepatic fibrosis induced by chronic carbon

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    by chronic carbon tetrachloride intoxication in rats Marie-No le Chobertë 1 # , Dominique Couchie 1 # , Agn, Myelomonocytic ; analysis ; Carbon Tetrachloride ; toxicity ; Epithelial-Mesenchymal Transition ; Keratin-19 of LPC, using a new experimental model in which rat liver fibrosis was induced by chronic carbon

  20. Lessons from a rare disease

    E-Print Network [OSTI]

    Dutchen, Stephanie Lynn

    2009-01-01T23:59:59.000Z

    Progeria is a genetic aging disease of childhood affecting an estimated one in four to eight million births. Children with progeria experience a range of developmental disorders and aging-like symptoms, including wrinkled ...

  1. A Manual of Poultry Diseases.

    E-Print Network [OSTI]

    Hall, C. F.; Bell, R. R.; Clifford, R. L., Jr.; Glass, S. E.; Grimes, J. E.; Grumbles, L. C.; Keahey, E. E.; Wormell, B. C.

    1971-01-01T23:59:59.000Z

    surrounding the term "sanitation" can be avoided by using the expression "management and sanitation for disease preven- , tion." This phrase then would be defined as all practices, specific and nonspecific, that the poultry- man applies to ptevent.... Change litter and thoroughly clean and disinfect the house and equipment between each group of birds. While litter selection and management is a large subject, applying this recommendation as a general practice will prevent many disease and parasite...

  2. Diarrheal Disease in Show Swine

    E-Print Network [OSTI]

    Lawhorn, D. Bruce

    2007-02-27T23:59:59.000Z

    cause disease in humans. Contaminated water is the main source of Giardia spp. Bacterial Causes Swine dysentery or ?bloody dysentery? from infec- tion with Brachyspira (Serpulina) hyodysenteriae is a major cause of diarrheal disease in show pigs... (the same area as whipworms) and prevents reabsorption of fluids. Affected pigs severe- ly dehydrate and up to 30 percent can die. Most affected pigs will drink but will not eat. Pigs that recover are intermittent shedders of B. hyodysenteriae and are a...

  3. Investigation of the Integration of Interstitial Building Spaces on Costs and Time of Facility Maintenance for U.S. Army Hospitals

    E-Print Network [OSTI]

    Leveridge, Autumn Tamara

    2013-04-30T23:59:59.000Z

    Huachuca, AZ Bliss Army Health Center Western Fort Carson, CO Evans Army Community Hospital Western Fort Leonard Wood, MO General Leonard Wood Army Community Hospital Western Fort Riley, KS Irwin Army Community Hospital Western Joint Base Lewis...-McChord, WA Madigan Army Medical Center Western Fort Leavenworth, KS Munson Army Health Center Western Fort Irwin, CA Weed Army Community Hospital Western Fort Bliss, TX William Beaumont Army Medical Center Of these, twelve U.S. Army hospitals were...

  4. Demonstration of Advanced Technologies for Multi-Load Washers in Hospitality and Healthcare – Ozone Based Laundry Systems

    SciTech Connect (OSTI)

    Boyd, Brian K.; Parker, Graham B.; Petersen, Joseph M.; Sullivan, Greg; Goetzler, W.; Sutherland, T. A.; Foley, K. J.

    2014-08-14T23:59:59.000Z

    The objective of this demonstration project was to evaluate market-ready retrofit technologies for reducing the energy and water use of multi-load washers in healthcare and hospitality facilities. Specifically, this project evaluated laundry wastewater recycling technology in the hospitality sector and ozone laundry technology in both the healthcare and hospitality sectors. This report documents the demonstration of ozone laundry system installations at the Charleston Place Hotel in Charleston, Sout Carolina, and the Rogerson House assisted living facility in Boston, Massachusetts.

  5. E-Print Network 3.0 - atherothrombotic cardiovascular disease...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    disease, the number one killer of all Americans. Cardiovascular disease, or heart disease is the primary cause Summary: Kidney disease is both a cause and a consequence...

  6. Factors Associated with the Decision to Hospitalize Emergency Department Patients with a Skin and Soft Tissue Infection

    E-Print Network [OSTI]

    2015-01-01T23:59:59.000Z

    Staphylococcus aureus (MRSA). 2 Hospitalizations for SSTICo-morbidity - n (%) Any Prior MRSA infection Diabetesmagnetic resonance imaging; MRSA, methicillin-resistant S.

  7. Exploratory Use of Microaerosol Decontamination Technology (PAEROSOL) in Enclosed, Unoccupied Hospital Setting

    SciTech Connect (OSTI)

    Rainina, Evguenia I.; McCune, D. E.; Luna, Maria L.; Cook, J. E.; Soltis, Michele A.; Demons, Samandra T.; Godoy-Kain, Patricia; Weston, J. H.

    2012-05-31T23:59:59.000Z

    The goal of this study was to validate the previously observed high biological kill performance of PAEROSOL, a semi-dry, micro-aerosol decontamination technology, against common HAI in a non-human subject trial within a hospital setting of Madigan Army Medical Center (MAMC) on Joint Base Lewis-McChord in Tacoma, Washington. In addition to validating the disinfecting efficacy of PAEROSOL, the objectives of the trial included a demonstration of PAEROSOL environmental safety, (i.e., impact to hospital interior materials and electronic equipment exposed during testing) and PAEROSOL parameters optimization for future deployment.

  8. Heart Disease and Early Heart Attack Care

    E-Print Network [OSTI]

    Ohta, Shigemi

    Heart Disease and Early Heart Attack Care Pamela Kostic, RN, CCCC, Chest Pain Coordinator, Stony Risk Factors · EHAC & Prevention #12;Heart disease includes a number of problems affecting the heart and the blood vessels in the heart. #12;Types of heart disease include: · Coronary artery disease (CAD) · Angina

  9. Mechanical Recanalization of Subacute Vessel Occlusion in Peripheral Arterial Disease with a Directional Atherectomy Catheter

    SciTech Connect (OSTI)

    Massmann, Alexander, E-mail: Alexander.Massmann@uks.eu; Katoh, Marcus [Saarland University Hospital, Department of Diagnostic and Interventional Radiology (Germany); Shayesteh-Kheslat, Roushanak [Saarland University Hospital, Department of General Surgery, Visceral, Vascular, and Pediatric Surgery (Germany); Buecker, Arno [Saarland University Hospital, Department of Diagnostic and Interventional Radiology (Germany)

    2012-10-15T23:59:59.000Z

    Purpose: To retrospectively examine the technical feasibility and safety of directional atherectomy for treatment of subacute infrainguinal arterial vessel occlusions. Methods: Five patients (one woman, four men, age range 51-81 years) with peripheral arterial disease who experienced sudden worsening of their peripheral arterial disease-related symptoms during the last 2-6 weeks underwent digital subtraction angiography, which revealed vessel occlusion in native popliteal artery (n = 4) and in-stent occlusion of the superficial femoral artery (n = 1). Subsequently, all patients were treated by atherectomy with the SilverHawk (ev3 Endovascular, USA) device. Results: The mean diameter of treated vessels was 5.1 {+-} 1.0 mm. The length of the occlusion ranged 2-14 cm. The primary technical success rate was 100%. One patient experienced a reocclusion during hospitalization due to heparin-induced thrombocytopenia. There were no further periprocedural complications, in particular no peripheral embolizations, until hospital discharge or during the follow-up period of 1 year. Conclusion: The recanalization of infrainguinal arterial vessel occlusions by atherectomy with the SilverHawk device is technically feasible and safe. In our limited retrospective study, it was associated with a high technical success rate and a low procedure-related complication rate.

  10. Radiologic atlas of rheumatic diseases

    SciTech Connect (OSTI)

    Dihlmann, W.

    1986-01-01T23:59:59.000Z

    This book is an ''atlas of rheumatic joint disease'' selected from 20 years of personal experience by the author. The author sets a goal of demonstrating the value of soft-tissue imaging in the diagnosis of early joint disease. This goal is achieved with high quality reproductions, many of which are presented in duplicate to illustrate bone and soft-tissue changes. The contents include an introductory overview of the ''Mosaic of Arthritis'' followed by sections on adult rheumatoid arthritis, seronegative spondyloarthropathies, classic collagen disease, enthesiopathies, and lastly a section on gout and psuedogout. The subject index is specific and indexes figures with boldface type. Each section is introduced by a brief outline or overview of the radiographic spectrum of the joint disorder to be illustrated.

  11. 1. Introduction A man is rushed to a hospital in the throes of a heart attack.

    E-Print Network [OSTI]

    Cottrell, Garrison W.

    1. Introduction A man is rushed to a hospital in the throes of a heart attack. The doctor needs when a heart attack patient is admitted, rank them accord- ing to their importance, and combine them heart attack patients according to risk using only a maxi- mum of three variables. If a patient has had

  12. University of Connecticut Health Center Page 1 of 2 John Dempsey Hospital

    E-Print Network [OSTI]

    Oliver, Douglas L.

    of infectivity. Other body substances are also considered hazardous. 3. Items or surfaces contaminated with blood/body fluids will be disinfected as specified in this protocol. 4. Departments in the hospital, which process or is to be ruled out for CJD, the electrodes used during the procedure are to be discarded into "Red-Bag" waste. 4

  13. Adult Routine Physical This health plan covers routine physical exams furnished by a General Hospital, Community

    E-Print Network [OSTI]

    Oppo, Delia W.

    covered related services). 1 #12;Pediatric Routine Physical This health plan covers routine pediatric careAdult Routine Physical This health plan covers routine physical exams furnished by a General Hospital, Community Health Center, Physician, Nurse Practitioner, Nurse Midwife or Independent Lab

  14. Quality site seasonal report: Cherokee Indian Hospital, SFBP 4058, December 1984 through April 1985

    SciTech Connect (OSTI)

    Raymond, M.G.

    1987-10-15T23:59:59.000Z

    The active solar Domestic Hot Water (DHW) and space heating system at the Cherokee Indian Hospital was designed and constructed as part of the Solar in Federal Buildings Program (SFBP). This retrofitted system is one of eight of the systems in the SFBP selected for quality monitoring. The purpose of this monitoring effort is to document the performance of quality state-of-the-art solar systems in large federal building applications. The hospital serves the Qualla Reservation of the Cherokee Indian Tribe in Cherokee, North Carolina, near the eastern entrance to the Great Smoky Mountain National Park. Solar energy is used to preheat domestic hot water (the cafeteria is the principal load) and for space heating. The hospital is expected to have a normal year-round occupancy of 200 people (patients, medical and maintenance personnel) with some 2775 expected visitors per year. The drainback solar system has 320 Owens-Illinois evacuated-tube collectors with a gross area of 5517 square feet. Solar energy is stored in a 6335-gallon storage tank. Solar energy from storage is supplied to a 700-gallon DHW preheat tank through a heat exchanger in the storage tank, and directly to heat exchangers in the heating ducts. Auxiliary energy is supplied by two large oil-fired boilers. Performance of the system at the Cherokee Indian Hospital during the period December 1984 through April 1985 are reported.

  15. Finding Your Way at Dana-Farber/Children's Hospital Cancer Center

    E-Print Network [OSTI]

    Liu, Xiaole Shirley

    cancer center with the expertise of a world-class pediatric hospital. Our unique program offers North · Operating Rooms, Main Building 3 · Neuro-Oncology Unit, 9 North · Radiology Department is the Blum Pediatric Resource Room. Outpatient Pharmacy (Y2) A centrally located outpatient pharmacy offers

  16. The internship in Corporate Communications at Beaumont Hospital, Royal Oak is affiliated with one of the

    E-Print Network [OSTI]

    Cinabro, David

    The internship in Corporate Communications at Beaumont Hospital, Royal Oak is affiliated with one atmosphere and Beaumont is a great place to work! Beaumont Internship 3601 W. 13 Mile Road Royal Oak, MI 48073 Rebecca Calappi internship coordinator rcalappi@beaumont.edu Intern with Beaumont Health System

  17. Cognitive Impairment in "Non-Neurologic" Elderly Hospital Inpatients Woods, A.J., & Mark, V.W.

    E-Print Network [OSTI]

    Chatterjee, Anjan

    Cognitive Impairment in "Non-Neurologic" Elderly Hospital Inpatients Woods, A.J., & Mark, V.W. University of Alabama at Birmingham Abstract Cognitive decline with aging is well documented. Cognitive. However, it is unclear whether elderly patients hospitalized for such disorders suffer cognitive decline

  18. Environmental Contributions to Allergic Disease

    E-Print Network [OSTI]

    Levetin, Estelle

    with increased exposure to air pollution and indoor contaminants such as house dust mites, cockroaches linked to the severity of allergic disease. The contribution of house dust mites, cockroaches, animal some of the strongest evidence sug- gests a compelling link between exposure to passive smoking

  19. The influence of contagion information and behavior on older adolescents' perceptions of peers with chronic illness

    E-Print Network [OSTI]

    Grizzle, Jonhenry Cordell

    2005-11-01T23:59:59.000Z

    To explore attributions about chronically ill peers, 545 older adolescents ages 17-26 read a short vignette describing a brief social encounter with a hypothetical peer suffering from a medical condition, and then responded to a series...

  20. Viral delivery of recombinant growth hormone to rescue effects of chronic stress on hippocampal learning

    E-Print Network [OSTI]

    Saenz, Christopher M

    2012-01-01T23:59:59.000Z

    Chronic stress has been linked to variation in gene regulation in the hippocampus (HIP) among other areas. These lead to cytoskeletal and volumetric rearrangements in various nuclei of the central nervous system and are ...

  1. Reactive species and DNA damage in chronic inflammation: Reconciling chemical mechanisms and biological fates

    E-Print Network [OSTI]

    Lonkar, Pallavi

    Chronic inflammation has long been recognized as a risk factor for many human cancers. One mechanistic link between inflammation and cancer involves the generation of nitric oxide, superoxide and other reactive oxygen and ...

  2. Transcranial LED therapy for cognitive dysfunction in chronic, mild traumatic brain injury: Two case reports

    E-Print Network [OSTI]

    Hamblin, Michael R.

    Two chronic, traumatic brain injury (TBI) cases are presented, where cognitive function improved following treatment with transcranial light emitting diodes (LEDs). At age 59, P1 had closed-head injury from a motor vehicle ...

  3. Acute and chronic toxicity of municipal landfill leachate as determined with bioassays and chemical analysis

    E-Print Network [OSTI]

    Schrab, Gregory Ernst

    1990-01-01T23:59:59.000Z

    municipal landfill leachates were determined to have mean estimated cumulative cancer risks on the same order of magnitude (10 4) as leachates from co-disposal and hazardous waste landfills. The use of a battery of acute and chronic toxicity bioassays..., chemical analysis, and an estimated cancer risk calculation resulted in data providing evidence that municipal solid waste landfill leachates are as acutely and chronically toxic as co-disposal and hazardous waste landfill leachates. ACKNOWLEDGEMENTS...

  4. Cough REVIEW Diagnosis and treatment of chronic cough in China: an insight into the status quo

    E-Print Network [OSTI]

    Kefang Lai; Wei Luo; Guangqiao Zeng; Nanshan Zhong

    Chronic cough is a very common complaint in clinics throughout China. Clinical and basic science research on chronic cough started late, but in recent years the effort has yielded promising findings regarding the etiological diagnosis, treatment and pathogenesis. We found that inflammation in nonasthmatic eosinophilic bronchitis has some similarities to cough variant asthma but also a number of distinct differences. Recent evidence has also suggested a mechanistic link between airway neurogenic inflammation and and gastroesophageal reflux cough (GERC). Cough-related animal models have been developed, including models for esophageal reflux, nonasthmatic eosinophilic bronchitis and allergic rhinitis. Normal reference values for differential cell counts in induced sputum, cough sensitivity and esophageal 24-h pH monitoring in Chinese healthy subjects have been established. By using a modified algorithm for the etiological diagnosis of chronic cough, the causes of chronic cough have been investigated across a number of cities in China. The most common causes of chronic cough are cough variant asthma, eosinophilic bronchitis, upper airway cough symptoms, atopic cough and GERC, however, there are some regional variations. The Chinese National Guidelines on Diagnosis and Management of Chronic Cough were drafted in 2005, updated in 2009, and have been widely publicized and disseminated through many channels since their publication.

  5. Why Do We Get Alzheimer's Disease?

    SciTech Connect (OSTI)

    Wyss-Coray, Tony (Stanford University) [Stanford University

    2006-01-02T23:59:59.000Z

    Neurodegenerative diseases and Alzheimer's disease (AD) in particular, are among the major health concerns of the elderly in industrialized societies. The cause of AD is unknown and no disease-modifying treatments are available. The disease is characterized clinically by a progressive dementia and pathologically by the accumulation of protein aggregates in the brain and a profound loss of nerve cells. It has also become clear recently that local immune responses are activated in the AD brain and may have a role in the disease. Our laboratory uses genetic mouse models to understand the disease process and to identify potential therapeutic targets.

  6. A study of organizational alignment at a Boston area hospital and its effects on patient throughput in the peri-operative areas

    E-Print Network [OSTI]

    Campbell, Sarah K. (Sarah Katharine)

    2007-01-01T23:59:59.000Z

    Capacity is an ongoing issue when managing hospital resources. Looking at the hospital as a supply chain of care services provided to the patient enables us to better evaluate problems such as delays on a systems level. A ...

  7. Neurological Complications Following Endoluminal Repair of Thoracic Aortic Disease

    SciTech Connect (OSTI)

    Morales, J. P.; Taylor, P. R.; Bell, R. E.; Chan, Y. C. [Guy's and St. Thomas' Foundation Hospital NHS Trust, Department of Vascular Surgery (United Kingdom); Sabharwal, T. [Guy's and St. Thomas' Foundation Hospital NHS Trust, Department of Interventional Radiology (United Kingdom); Carrell, T. W. G. [Guy's and St. Thomas' Foundation Hospital NHS Trust, Department of Vascular Surgery (United Kingdom); Reidy, J. F. [Guy's and St. Thomas' Foundation Hospital NHS Trust, Department of Interventional Radiology (United Kingdom)], E-mail: John.Reidy@gstt.nhs.uk

    2007-09-15T23:59:59.000Z

    Open surgery for thoracic aortic disease is associated with significant morbidity and the reported rates for paraplegia and stroke are 3%-19% and 6%-11%, respectively. Spinal cord ischemia and stroke have also been reported following endoluminal repair. This study reviews the incidence of paraplegia and stroke in a series of 186 patients treated with thoracic stent grafts. From July 1997 to September 2006, 186 patients (125 men) underwent endoluminal repair of thoracic aortic pathology. Mean age was 71 years (range, 17-90 years). One hundred twenty-eight patients were treated electively and 58 patients had urgent procedures. Anesthesia was epidural in 131, general in 50, and local in 5 patients. Seven patients developed paraplegia (3.8%; two urgent and five elective). All occurred in-hospital apart from one associated with severe hypotension after a myocardial infarction at 3 weeks. Four of these recovered with cerebrospinal fluid (CSF) drainage. One patient with paraplegia died and two had permanent neurological deficit. The rate of permanent paraplegia and death was 1.6%. There were seven strokes (3.8%; four urgent and three elective). Three patients made a complete recovery, one had permanent expressive dysphasia, and three died. The rate of permanent stroke and death was 2.1%. Endoluminal treatment of thoracic aortic disease is an attractive alternative to open surgery; however, there is still a risk of paraplegia and stroke. Permanent neurological deficits and death occurred in 3.7% of the patients in this series. We conclude that prompt recognition of paraplegia and immediate insertion of a CSF drain can be an effective way of recovering spinal cord function and improving the prognosis.

  8. Development and Analytical Validation of an Enzyme-linked Immunosorbent Assay (ELISA) for the Measurement of Feline Alpha1-proteinase Inhibitor (fa1-PI) in Serum and Feces and the Evaluation of Fecal fa1-PI Concentrations in Cats with Idiopathic Inflammatory Bowel Disease or Gastrointestinal Neoplasia

    E-Print Network [OSTI]

    Burke, Kathrin

    2012-10-19T23:59:59.000Z

    in feces and serum from cats, and, second, to evaluate fecal alpha1-PI concentrations in healthy cats and cats with chronic gastrointestinal disease. The lower detection limits of the ELISA were 0.02 g/L for serum and 0.04 microgram/gram for feces...

  9. New Clues in Predicting Alzheimer's Disease

    ScienceCinema (OSTI)

    Jagust, William

    2013-05-29T23:59:59.000Z

    Theres a new clue in the search to identify the harbingers of Alzheimers disease. More info: http://newscenter.lbl.gov/feature-stories/2008/12/16/predict-alzheimers-disease/

  10. Scoping Report: Advanced Technologies for Multi-Load Washers in Hospitality and Healthcare

    SciTech Connect (OSTI)

    Parker, Graham B.; Boyd, Brian K.; Petersen, Joseph M.; Goetzler, W.; Foley, K. J.; Sutherland, T. A.

    2013-03-27T23:59:59.000Z

    The purpose of this demonstration project is to quantify the energy savings and water efficiency potential of commercial laundry wastewater recycling systems and low-temperature detergent supply systems to help promote the adoption of these technologies in the commercial sector. This project will create a set of technical specifications for efficient multi-load laundry systems (both new and retrofit) tailored for specific applications and/or sectors (e.g., hospitality, health care). The specifications will be vetted with the appropriate Better Buildings Alliance (BBA) members (e.g., Commercial Real Estate Energy Alliance, Hospital Energy Alliance), finalized, published, and disseminated to enable widespread technology transfer in the industry and specifically among BBA partners.

  11. AFBC co-firing of coal and hospital waste. Quarterly report, February - April, 1996

    SciTech Connect (OSTI)

    Stuart, J.M.

    1996-12-31T23:59:59.000Z

    The project objective is to design, construct, install provide operator training and start-up a circulating fluidized bed combustion system at the Lebanon Pennsylvania Veteran`s Affairs Medical Center. This unit will co-fire coal and hospital waste providing lower cost steam for heating and possibly cooling (absorption chiller) and operation of a steam turbine-generator for limited power generation while providing efficient destruction of both general and infectious hospital waste. The steam generated is as follows: steam = 20,000 lb/hr; temperature = 353 F (saturated); pressure = 125 psig; and steam quality = {approximately}98.5%. During this reporting period: structural corrections have been made to make the facility meet the required building costs; and refractory bakeout was successfully completed during April 23-25, 1996 over a 54 -hour period. Operating permits will be obtained after construction has been completed.

  12. LED Surgical Task Lighting Scoping Study: A Hospital Energy Alliance Project

    SciTech Connect (OSTI)

    Tuenge, Jason R.

    2011-01-17T23:59:59.000Z

    Tungsten-halogen (halogen) lamps have traditionally been used to light surgical tasks in hospitals, even though they are in many respects ill-suited to the application due to the large percentage of radiant energy outside the visible spectrum and issues with color rendering/quality. Light-emitting diode (LED) technology offers potential for adjustable color and improved color rendition/quality, while simultaneously reducing side-effects from non-visible radiant energy. It also has the potential for significant energy savings, although this is a fairly narrow application in the larger commercial building energy use sector. Based on analysis of available products and Hospital Energy Alliance member interest, it is recommended that a product specification and field measurement procedure be developed for implementation in demonstration projects.

  13. MENINGOCOCCAL DISEASE WHAT YOU NEED TO KNOW

    E-Print Network [OSTI]

    Missouri-Rolla, University of

    , coughing and having close social contact (living in the same household) are examples of how this disease

  14. 1 | P a g e FACT SHEET: UCSF Benioff Children's Hospital Oakland

    E-Print Network [OSTI]

    Klein, Ophir

    donor cord blood bank, leading to children being cured of sickle cell disease and most comprehensive sickle cell and thalassemia program in the Western United

  15. Heart Valve Disease James S. Gammie, MD

    E-Print Network [OSTI]

    Weber, David J.

    Heart Valve Disease James S. Gammie, MD Professor and Chief Division of Cardiac Surgery University USA Source: CDC #12;#12;CARDIOTHORACIC SURGEON: A SURGEON THAT TREATS HEART AND LUNG DISEASE #12;Valvular Heart Disease: Common and Under-diagnosed 0 2 4 6 8 10 12 14 18 - 44 45 - 54 55 - 64 65 - 74 > 75

  16. Coronary Heart Disease, Hypertension, Stroke, and

    E-Print Network [OSTI]

    Meagher, Mary

    Coronary Heart Disease, Hypertension, Stroke, and Diabetes #12;Coronary Heart Disease: Overview by atherosclerosis ­ Narrowing of coronary arteries, the vessels that supply the heart · Disease process: coronary and arms Myocardial infarction - heart attack, ischemia - local blood supply decreased resulting in cell

  17. Examining Change in Symptoms of Depression, Anxiety, and Stress in Adults after Treatment of Chronic Cough: A Dissertation.

    E-Print Network [OSTI]

    French, Cynthia L.

    2014-01-01T23:59:59.000Z

    ??Background: Chronic cough is a common health problem with variable success rates to standardized treatment. Psychologic symptoms of depression, anxiety, and stress have been reported… (more)

  18. Controlling Diseases on Ornamental Plants.

    E-Print Network [OSTI]

    Horne, C. Wendell; Johnson, Jerral D.; Walla, Walter J.

    1979-01-01T23:59:59.000Z

    powder is used as a spray to control powdery mildew and foliage diseases. It is available as Daconil 2787?, Bravo? and Ferti-Iome Broad Spectrum Liquid Fungicide?. Formaldehyde: This is a 37 percent solution in water and methanol which is used... and move it over the loosened soil. Drain tile or iron pipe buried in the soil helps to distribute the ste~m. Heat the soil until a medium-sized potato buried several inches deep is cooked thoroughly. Use formaldehyde as manufacturer directs. Water...

  19. aquatic animal diseases: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    William R. Pritchard Veterinary Medical Teaching Hospital University serving as a fish health specialist at the University of Arkansas; Animal Health Manager at the New...

  20. The Demographic Characteristics of Patients Seeking Health Care for Infant and Childhood Illnesses at Nepal Medical College and Teaching Hospital

    E-Print Network [OSTI]

    Pandey, Kishore Raj; Kafle, Phanindra Prasad; Karki, Debendra

    2003-01-01T23:59:59.000Z

    THE DEMOGRAPHIC CHARACTERISTICS OF PATIENTS SEEKING HEALTH CARE FOR INFANT AND CHILDHOOD ILLNESSES AT NEPAL MEDICAL COLLEGE AND TECHNING HOSPITAL Kishore Raj Pandey' Phanindra Prasad Kane Debendra Karki Abstract:. This paper presents the demographic... characteristics of 424 patients and their parents/guardians over a four month period seeking health care for infant and childhood illnesses at Nepal Medical College and Teaching Hospital which is located at the outskirts of the Kathmandu Valley. The objective...

  1. Chronic cellular responses of rat skin to 13 Mev proton irradiation

    E-Print Network [OSTI]

    Hinkle, Donald King

    1966-01-01T23:59:59.000Z

    CHRONIC CELLULAR RESPONSES OF RAT SKIN TO 13 MEV PROTON IRRADIATION A Thesis by DONALD KING HINKLE, D. V. M. Submitted to the Graduate College of the Texas AErM University in partial fulfillment of the requirements for the degree of MASTER... OF SCIENCE August 1966 Major Subject: Laboratory Animal Medicine CHRONIC CELLULAR RESPONSES OF RAT SKIN TO 13 MEV PROTON IRRADIATION A Thesis by DONALD KING HINKLE, D. V. M. Submitted to the Graduate College of the Texas ARM University in partial...

  2. Cardiac Procedures among American Indians and Alaska Natives compared to Non-Hispanic Whites Hospitalized with Ischemic Heart Disease in California

    E-Print Network [OSTI]

    Jolly, Stacey; Kao, Chi; Bindman, Andrew B.; Korenbrot, Carol

    2010-01-01T23:59:59.000Z

    catheterization, percutaneous coronary intervention, and88.57); percutaneous coronary intervention (37.22, 37.23,catheterization or percutaneous coronary intervention in the

  3. Cardiac Procedures among American Indians and Alaska Natives compared to Non-Hispanic Whites Hospitalized with Ischemic Heart Disease in California

    E-Print Network [OSTI]

    Jolly, Stacey; Kao, Chi; Bindman, Andrew B.; Korenbrot, Carol

    2010-01-01T23:59:59.000Z

    Jolly et al. : Cardiac Procedures among American Indians anduse of invasive cardiac procedures among cardiac patients inthe use of cardiovascular procedures: associations with type

  4. Therapeutic target for protozoal diseases

    DOE Patents [OSTI]

    Rathore, Dharmendar (Blacksburg, VA); Jani, Dewal (Blacksburg, VA); Nagarkatti, Rana (Blacksburg, VA)

    2008-10-21T23:59:59.000Z

    A novel Fasciclin Related Adhesive Protein (FRAP) from Plasmodium and related parasites is provided as a target for therapeutic intervention in diseases caused by the parasites. FRAP has been shown to play a critical role in adhesion to, or invasion into, host cells by the parasite. Furthermore, FRAP catalyzes the neutralization of heme by the parasite, by promoting its polymerization into hemozoin. This invention provides methods and compositions for therapies based on the administration of protein, DNA or cell-based vaccines and/or antibodies based on FRAP, or antigenic epitopes of FRAP, either alone or in combination with other parasite antigens. Methods for the development of compounds that inhibit the catalytic activity of FRAP, and diagnostic and laboratory methods utilizing FRAP are also provided.

  5. Chronic heart rate reduction with ivabradine improves systolic function of the reperfused heart through a dual mechanism involving a direct

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Chronic heart rate reduction with ivabradine improves systolic function of the reperfused heart.berdeaux@inserm.fr inserm-00500900,version1-12Jul2010 Author manuscript, published in "European heart journal 2010 function and calcium handling to chronic heart rate reduction with ivabradine in the reperfused heart

  6. Prognostic Significance and Normal Values of 2D Strain to Assess Right Ventricular Systolic Function in Chronic Heart Failure

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Function in Chronic Heart Failure Short Title: RV dysfunction and prognosis in CHF Soulef Guendouz, MD1 Journal 2012;76(1):127-36" #12;2 ABSTRACT Aims: Chronic heart failure (CHF) has a poor prognosis. Our aims or emergent transplantation or emergent ventricular assist-device implantation or acute heart failure. RV-2D

  7. Geothermal heating project at St. Mary's Hospital, Pierre, South Dakota. Final report

    SciTech Connect (OSTI)

    Not Available

    1984-12-01T23:59:59.000Z

    St. Mary's Hospital, Pierre, South Dakota, with the assistance of the US Department of Energy, drilled a 2176 ft well into the Madison Aquifer ot secure 108/sup 0/F artesian flow water at 385 gpm (475 psig shut-in pressure). The objective was to provide heat for domestic hot water and to space heat 163,768 sq. ft. Cost savings for the first three years were significant and, with the exception of a shutdown to replace some corroded pipe, the system has operated reliably and continuously for the last four years.

  8. Positron Emission Tomography-Scanner at Children`s Hospital of Michigan at Detroit, Michigan

    SciTech Connect (OSTI)

    Not Available

    1992-12-31T23:59:59.000Z

    The Department of Energy has prepared an environmental assessment (EA), DOE/EA-0795, to support the DOE decision to provide a grant of $7,953,600 to be used in support of a proposed Positron Emission Tomography Scanner at Children`s Hospital of Michigan at Detroit, Michigan. Based upon the analysis in the EA, DOE has determined that the proposed action is not a major Federal action significantly affected the quality of the human environment within the meaning of the National Environmental Policy Act of 1969 (NEPA). Therefore, the preparation of an Environmental Impact Statement is not required and DOE is issuing this Finding of No Significant Impact (FONSI).

  9. Cogeneration System Analysis Summary Reports for Austin State Hospital, Austin, Texas

    E-Print Network [OSTI]

    Turner, W. D.; Murphy, W. E.; Hartman, R.; Heffington, W. M.; Bolander, J. N.; Propp, A. D.

    1985-01-01T23:59:59.000Z

    and 1.3 MW. For at least one scenario of fuel price escalation, a larger size (1.3 MW) would be preferred based upon this analysis, if no standby power charges occurred. The gas turbine system could be installed at one of various sites at the hospital... cost escalation above inflation, the 1.0 MW (1000kW) system shows an NPV from 1.0 million dollars to 1.8 million dollars depending on the standby charge. The other curve shown in each graph is for the case when the escalation rates for electricity...

  10. A Method to Estimate the Chronic Health Impact of Air Pollutants in

    E-Print Network [OSTI]

    to disease. Results: PM2.5, acrolein, and formaldehyde accounted for the vast majority of DALY losses caused

  11. Investigating organizational quality improvement systems, patient empowerment, organizational culture, professional involvement and the quality of care in European hospitals: the 'Deepening our Understanding of Quality Improvement in Europe (DUQuE)' project

    E-Print Network [OSTI]

    2010-01-01T23:59:59.000Z

    of hospital quality management systems in the Netherlands.accreditation systems, orga- nisational quality management

  12. Fracture, aging and disease in bone

    E-Print Network [OSTI]

    Ager, J.W.; Balooch, G.; Ritchie, R.O.

    2006-01-01T23:59:59.000Z

    on glucocorticoid-induced osteoporosis. Rheumatic DiseaseGlucocorticoid-induced osteoporosis. Endocrinol Metab. Clin.of cortico-steroid osteoporosis. A meta-analysis. Osteoporos

  13. "Artificial" brains, electrical grids, and disease modeling:...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Science discoveries unveiled "Artificial" brains, electrical grids, and disease modeling: Los Alamos science discoveries unveiled September 15 The event is an opportunity for...

  14. Functional cardiovascular assessment in congenital heart disease.

    E-Print Network [OSTI]

    W.J.B.W. van den Berg

    2007-01-01T23:59:59.000Z

    ??abstractAdequate and serial functional cardiovascular assessment is important in patients with congenital heart disease because many show disruption of normal myocardial geometry, which may or… (more)

  15. Enzyme replacement therapy for Pompe disease

    E-Print Network [OSTI]

    Burris, Ryan Jonathan William

    2010-01-01T23:59:59.000Z

    CALIFORNIA, SAN DIEGO Enzyme Replacement Therapy for Pompe3 1.3 Enzyme Replacement Therapy for Pompe Disease…………………… 5Receptor ERT – Enzyme Replacement Therapy LSD – Lysosomal

  16. Beneficial Effects of Hematopoietic Growth Factor Therapy in Chronic Ischemic Stroke in Rats

    E-Print Network [OSTI]

    Apkarian, A. Vania

    Beneficial Effects of Hematopoietic Growth Factor Therapy in Chronic Ischemic Stroke in Rats Li. Vania Apkarian, PhD; John A. Kessler, MD Background and Purpose--Stroke is the leading cause of adult disability worldwide. Currently, there is no effective treatment for stroke survivors. Stem cell factor (SCF

  17. Water balance in rats exposed to chronic centrifugation RUDY M. ORTIZ AND CHARLES E. WADE

    E-Print Network [OSTI]

    Ortiz, Rudy M.

    was observed, the lack of a change in %TBW among the three measurement periods or in water flux over the 12Water balance in rats exposed to chronic centrifugation RUDY M. ORTIZ AND CHARLES E. WADE Life; accepted in final form 22 February 2000 Ortiz, Rudy M., and Charles E. Wade. Water balance in rats exposed

  18. The extent of chronic marine oil pollution in southeastern Newfoundland waters assessed through beached

    E-Print Network [OSTI]

    Jones, Ian L.

    on their feathers is heavy fuel oil mixed with lubricants, the mixture found in bilges of large vessels. BeachedThe extent of chronic marine oil pollution in southeastern Newfoundland waters assessed through America. Oiled seabirds have washed up on beaches in Newfoundland for many decades. Most oil

  19. Chronic water stress reduces tree growth and the carbon sink of deciduous hardwood forests

    E-Print Network [OSTI]

    Phillips, Richard P.

    have the potential to offset gains in carbon (C) uptake from phenology trends, rising atmospheric CO2Chronic water stress reduces tree growth and the carbon sink of deciduous hardwood forests E D W Institute of Technology, IMK-IFU, Garmisch-Partenkirchen 82467, Germany, 4 USDA Forest Service ­ SilvaCarbon

  20. Intoxication aigu et chronique au cadmium Acute and chronic cadmium poisoning

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    1 Intoxication aiguë et chronique au cadmium Acute and chronic cadmium poisoning Pascal ANDUJAR1 poisoning Summary (176 words): Key words : cadmium - poisoning - pneumonia - nephropathy - osteomalacia population are food and tobacco smoking. Its industrial exploitation has grown in the early twentieth century

  1. Design, Preparation and Activity of Cotton Gauze for Use in Chronic Wound Research

    SciTech Connect (OSTI)

    Edwards, J. V.; Yager, Dorne; Bopp, Alvin; Diegelmann, Robert F.; Goheen, Steven C.; Cohen, I. K.

    2001-01-01T23:59:59.000Z

    We consider the rational design and chemical modification of cotton gauze, which is used widely in chronic wounds, to improve wound dressing fibers for application to chronic wound healing. Cotton gauze may be tailored to more effectively enhance the biochemistry of wound healing. The presence of elevated levels of elastase in non-healing wounds has been associated with the degradation of important growth factors and fibronectin necessary for wound healing. In the healing wound a balance of elastase and antiproteases precludes degradation of beneficial proteins from taking place. Cotton gauze modified to release elastase inhibitors or selectively functionalized to sequester elastase provides a dressing that decreases high levels of destructive elastase in the chronic wounds. Three approaches have been taken to explore the potential of fiber-inhibitors useful in chronic wounds: 1) Formulation of inhibitors on the dressing; 2) Synthesis of elastase recognition sequences on cotton cellulose; and 3) Data presented here on carboxymethylating, and oxidizing textile finishes of cotton gauze to remove elastase from the wound.

  2. SPINAL CORD STIMULATION FOR CHRONIC PAIN MANAGEMENT: TOWARDS AN EXPERT SYSTEM

    E-Print Network [OSTI]

    Kreinovich, Vladik

    million of people in the United States only). Chronic pain may not be perceived as such a threat as cancer people than cancer or heart dis­ ease. It costs the US economy more than $90 billion per year in medical, a careful selec­ tion of weak electric currents drastically decreases the pain level. Engineering progress

  3. AFBC co-firing of coal and hospital waste. Quarterly report, August--October 1995

    SciTech Connect (OSTI)

    Stuart, J.M.

    1996-03-01T23:59:59.000Z

    The project objective is to design, construct, install provide operator training and start-up a circulating fluidized bed combustion system at the Lebanon Pennsylvania Veteran`s Affairs Medical Center. This unit will co-fire coal and hospital waste providing lower cost steam for heating and possibly cooling (absorption chiller) and operation of a steam turbine-generator for limited power generation. This would permit full capacity operation of the FBC year round in spite of the VA laundry that was shut down as well as efficient destruction of both general and infectious hospital waste and steam generation. The State permitting process required for construction will be completed in early November to allow installation and construction to be completed. Operating permits will be obtained after construction has been completed. A request for proposal for stack sampling and biospore tests was released to four (4) vendors in mid-October. The proposals shall be reviewed during November and the stack sampler will be selected. Funding was approved as of August 1, 1995. Construction and installation resumed on August 21, 1995 at the LVAMC. Construction and installation continues and will be completed by late December 1995.

  4. AFBC co-firing of coal and hospital waste. Quarterly report, November 1995--January 1996

    SciTech Connect (OSTI)

    Stuart, J.M.

    1996-03-01T23:59:59.000Z

    The project objective is to design, construct, install provide operator training and start-up a circulating fluidized bed combustion system at the Lebanon Pennsylvania Veteran`s Affairs Medical Center. This unit will co-fire coal and hospital waste providing lower cost steam for heating and possibly cooling (absorption chiller) and operation of a steam turbine-generator for limited power generation while providing efficient destruction of both general and infectious hospital waste. Operating permits will be obtained after construction has been completed. The stack sampler has been selected. This vendor is currently developing the testing protocol. Severe weather in December and January caused work delays to the project, especially to outside work The fabrication and installation of the stack are complete. Only the insulation of the stack remains to be done. Budget problems began to occur in late January. Correction of this situation should occur shortly in February or March. A current schedule for the project is included with this report.

  5. "Isokinetic Testing of Evertor and Invertor Muscles in Patients with Chronic Ankle Instability" by David P et al. Journal of Applied Biomechanics

    E-Print Network [OSTI]

    Boyer, Edmond

    "Isokinetic Testing of Evertor and Invertor Muscles in Patients with Chronic Ankle Instability of Evertor and Invertor Muscles in Patients with Chronic Ankle Instability Authors: Pascal David1 , Mohamad Muscles in Patients with Chronic Ankle Instability" by David P et al. Journal of Applied Biomechanics

  6. Are You at Risk for Heart Disease?

    E-Print Network [OSTI]

    Bandettini, Peter A.

    vessels going to the heart get narrow and clogged. A heart attack can happen when these blood vesselsAre You at Risk for Heart Disease? Healthy Heart, Healthy Family Nangangamba Ka Bang Magkaroon ng Are You at Risk for Heart Disease? Healthy Heart, Healthy Family Nangangamba Ka Bang Magkaroon ng Sakit sa

  7. PROTEIN INTERACTIONS AND DISEASE MARICEL KANN

    E-Print Network [OSTI]

    Radivojac, Predrag

    and illnesses, including AIDS, cancer, and Alzheimer's disease. The goal of this session is to discuss interaction data to identify active pathways re- lated to HIV pathogenesis. A functional analysis for successful inference of protein interactions. Chen et al. developed a framework to mine disease

  8. Coronary Heart Disease, Hypertension, Stroke, and

    E-Print Network [OSTI]

    Meagher, Mary

    Coronary Heart Disease, Hypertension, Stroke, and Diabetes #12;Coronary Heart Disease: Overview to illnesses caused by atherosclerosis ­ Narrowing of coronary arteries, the vessels that supply the heart that radiates across the chest and arms � Myocardial infarction - heart attack, ischemia - local blood supply

  9. HANFORD THYROID DISEASE STUDY FINAL REPORT

    E-Print Network [OSTI]

    HANFORD THYROID DISEASE STUDY FINAL REPORT Study Management Team Scott Davis, Ph.D., Principal;Acknowledgments Many individuals have contributed to the success of the Hanford Thyroid Disease Study. We wish: Dr. Floyd Frost and Mr. Eugene Sobota; 3) history of Hanford: Dr. Michelle Stenejhem; 4) statistical

  10. Journal of Wildlife Diseases, 41(1), 2005, pp. 4857 Wildlife Disease Association 2005

    E-Print Network [OSTI]

    Mladenoff, David

    REGION Michael D. Samuel,1,2,4 Daniel J. Shadduck,1 Diana R. Goldberg,1 and William P. Johnson3 1 US of methods developed in laboratory challenge trials (Samuel et al., 2003a) and a serotype- specific caerulescens) breeding colo- nies (Samuel et al., 1999a). In addition, chronic transmission and infection might

  11. X-ray atlas of rheumatic diseases

    SciTech Connect (OSTI)

    Dihlmann, W.

    1986-01-01T23:59:59.000Z

    This atlas comprises instructive X-rays of the various inflammatory rheumatic joint diseases in all stages at the extremities and the spinal column. In addition, the complex pattern of the wide range of arthroses, also known as degenerative rheumatic disease is included. Besides the instructive pointers to X-ray diagnosis, the book is also a guide to differential diagnosis. Hence, this book is actually an X-ray atlas of joint diseases in general. Selected Contents: Introduction: What Does ''Rheumatism'' Actually Mean./Radiographic Methodology in Rheumatic Diseases of the Locomotor System/The Mosaic of Arthritis/Adult Rheumatoid Arthritis/Seronegative Spondylarthritis/Classic Collagen Diseases/Enthesiopathies/Gout-Pseudogout

  12. INTRACRANIAL INJURY AND MORTALITY ASSOCIATED WITH MOTORCYCLE-RELATED HOSPITALIZATIONS: DIFFERENCES IN INCIDENCE AND COSTS ON THE BASIS OF UNIVERSAL MOTORCYCLE HELMET USE LEGISLATION IN THE UNITED STATES.

    E-Print Network [OSTI]

    Parker, Brenda Marie

    2011-01-01T23:59:59.000Z

    ??Intracranial Injury and Mortality Associated with Motorcycle-related Hospitalizations: Differences in Incidence and Costs on the Basis of Universal Motorcycle Helmet Use Legislation in the United… (more)

  13. AFBC co-firing of coal and hospital waste: Quarterly report, 1 May 1996-31 July, 1996

    SciTech Connect (OSTI)

    Stuart, J.M.

    1996-12-31T23:59:59.000Z

    The project objective is to design, construct, install, provide operator training and start-up a circulating fluidized bed combustion system at the Lebanon Pennsylvania Veteran`s Affairs Medical Center. This unit will co-fire coal and hospital waste providing lower cost steam for heating and possibly cooling (absorption chiller) and operation of a steam turbine-generator for limited power generation while providing efficient destruction of both general and infectious hospital waste. This quarterly report describes activities completed in the design, procure, install and start-up phase.

  14. AFBC co-firing of coal and hospital waste. Quarterly progress report, August 1--October 31, 1996

    SciTech Connect (OSTI)

    NONE

    1997-06-01T23:59:59.000Z

    The project objective is to design, construct, install, provide operator training and start-up a circulating fluidized bed combustion system at the Lebanon Pennsylvania Veteran`s Affairs Medical Center. This unit will co-fire coal and hospital waste providing lower cost steam for heating and possibly cooling (absorption chiller) and operation of a steam turbine-generator for limited power generation while providing efficient destruction of both general and infectious hospital waste. The steam generated as follows: (1) Steam = 20,000 lb/hr, (2) Temperature = 353 F (saturated), (3) Pressure = 125 psig, and (4) Steam quality = {approximately}98.5%.

  15. Hemodynamic characterization of chronic bile duct-ligated rats: effect of pentobarbital sodium

    SciTech Connect (OSTI)

    Lee, S.S.; Girod, C.; Braillon, A.; Hadengue, A.; Lebrec, D.

    1986-08-01T23:59:59.000Z

    Systemic and splanchnic hemodynamics of the chronic bile duct-ligated rat were characterized by radioactive microspheres. Conscious and pentobarbital sodium-anesthetized, bile duct-ligated and sham-operated rats had cardiac output and regional organ blood flows determined. The conscious bile duct-ligated rat compared with the sham-operated showed a hyperdynamic circulation with an increased cardiac output and portal tributary blood flow. Pentobarbital sodium anesthesia induced marked hemodynamic changes in both sham-operated and bile duct-ligated rats. The latter group was especially sensitive to its effects; thus, comparison of cardiac output and portal tributary blood flow between anesthetized bile duct-ligated and sham-operated rats showed no significant differences. The authors conclude that the rat with cirrhosis due to chronic bile duct ligation is an excellent model for hemodynamic investigations but should be studied in the conscious state, since pentobarbital sodium anesthesia eliminated the hyperdynamic circulation.

  16. Effects of chronic cadmium exposure on the conditioned reinforcing properties of morphine and fentanyl in rats

    E-Print Network [OSTI]

    Miller, Dennis K

    1997-01-01T23:59:59.000Z

    &M University in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE Approved as to style and content by: ck R. Nation (C ir of Committee) Gerald D. Frye (Member) Paul J. Wellman (Member) Paul J. Wellman (Head of Department... the metal (Nation, Livermore, Bratton, & Schenk, 1996). A similar attenuation was shown with repeated cocaine exposure--the development of locomotor sensitization. Rats that received chronic cadmium exposure required more cocaine administration sessions...

  17. Interstitial fluid pressure within the coronary dermis of the horse with chronic laminitis

    E-Print Network [OSTI]

    Olivier, Ann

    1987-01-01T23:59:59.000Z

    (IFP) in the coronary band at the toe and heel positions of the catheter in the forefeet of normal horses (Group 1, N 10) and horses with chronic laminitis (Group 2, N~10) 28 LIST OF FIGURES Figure Page I. Wick-in-needle catheter 17 2. Mean... manifestations including pain, various endocrine and electrolyte imbalances , hypertension, renal dysfunction& anorexia and depression 2, 3, 11-17 are also encountered The affected foot may undergo mechanical collapse as the relationship of the structures...

  18. Behavioral impulsivity and hallucinations : insights from Parkinson's disease

    E-Print Network [OSTI]

    Ashourian, Paymon

    2011-01-01T23:59:59.000Z

    Parkinson's disease (PD) is an age-related degenerative disease of the brain, characterized by motor, cognitive, and psychiatric symptoms. Neurologists and neuroscientists now understand that several symptoms of the disease, ...

  19. Microvascular function after treatment with an angiogenic factor, TP508, in a porcine model of chronic ischemia

    E-Print Network [OSTI]

    Makarski, Lori Ann

    2003-01-01T23:59:59.000Z

    function of microvessels in ischemic myocardium treated with TP508, (treated, TR) when compared to untreated ischemic myocardium (non-treated, NT) and non-ischemic myocardium from control pigs (CON). Adult Yucatan miniature swine were subjected to chronic...

  20. Improved Cognitive Function After Transcranial, Light-Emitting Diode Treatments in Chronic, Traumatic Brain Injury: Two Case Reports

    E-Print Network [OSTI]

    Naeser, Margaret A.

    Objective: Two chronic, traumatic brain injury (TBI) cases, where cognition improved following treatment with red and near-infrared light-emitting diodes (LEDs), applied transcranially to forehead and scalp areas, are ...

  1. HLB in Argentina: a New Disease Outbreak

    E-Print Network [OSTI]

    2014-01-01T23:59:59.000Z

    Vol. 1 (2014) HLB in Argentina: a New Disease Outbreak Outi,E. 6 SENASA, Bs. As. Argentina MAGyP Bs. As INTA Montecarlo,Paraná, 300 km away from Argentina’s Northeastern border. In

  2. INTERNATIONAL CENTRE FOR DIARRHOEAL DISEASE RESEARCH, BANGLADESH

    E-Print Network [OSTI]

    Scharfstein, Daniel

    ©INTERNATIONAL CENTRE FOR DIARRHOEAL DISEASE RESEARCH, BANGLADESH J HEALTH POPUL NUTR 2009 00 managers can target resources to identify if such clusters exist. If so, they can then ensure supervi

  3. What You Should Know About Plant Diseases.

    E-Print Network [OSTI]

    Horne, C. Wendell; Smith, Harlan E.

    1962-01-01T23:59:59.000Z

    when applied before the attack, thus serving as a preventive measure. With many crops, the occurrence of these attacks is predictable on the basis of past experience. Dusting Plants One may use dusts when controlling diseases with chemicals..., but they are not as effective as spraying. Usually, dusts shoultl be used to supple- ment sprays. Dust preparations are ready-mixed in the proper concentration, ready for application. Crop Rotation and Sanitation During the winter many plant disease organisms may live...

  4. Major Oak Diseases and Their Control.

    E-Print Network [OSTI]

    Johnson, Jerral D.; Appel, David N.

    1984-01-01T23:59:59.000Z

    )OC ?A245 Q7 173 . \\00 ILl78 , LIBRARY -?'?AUG 3 1?1S84 r ex.J$ MM University MAJOR OAK DISEASES AND THEIR CONTROL 8-1478 J ~ Texas Agricultural Extension Service. The Texas A&M University System ? Zerle L. Carpenter, Director. College... Station, Texas (Blaok Page bl-?OriglulBidletial? / . , ,;..,' ,- ; ~ ~ " OAK DISEASES AND THEIR CONTROL Jerral D. Johnson and David N. Appel* Oaks represent the major shade trees of Texas and are also...

  5. Molecular pathogenesis of Helicobacter hepaticus induced liver disease

    E-Print Network [OSTI]

    Boutin, Samuel R., 1952-

    2005-01-01T23:59:59.000Z

    Helicobacter hepaticus infection of A/JCr mice is a model of liver cancer resulting from chronic active inflammation. We monitored hepatic global gene expression profiles and correlated them to histological liver lesions ...

  6. An investigation of the potentiating effects of ethanol on a chronic exposure of rats to 1,1,1-trichloroethane

    E-Print Network [OSTI]

    Walker, DeWayne Harold

    1973-01-01T23:59:59.000Z

    AN INVESTIGATION OF THE POTENTIATING EFFECTS OF ETHANOL ON A CHRONIC EXPOSURE OF RATS TO 1, 1&I-TRICHLOROETHANE A Thesis by DEWAYNE HAROLD WALKER Submitted to the Graduate College of Texas AFM University in partial fulfillment... of the requirement for the degree of MASTER OF SCIENCE August 1973 Major Subject: Laboratory Animal Medicine AN INVESTIGATION OF THE POTENTIATING EFFECTS OF ETHANOL ON A CHRONIC EXPOSURE OF RATS TQ 1&1, 1-TRICHLOROETHANE A Thesis by DENAYNE HAROLD WALKER...

  7. MEDIMAGE A Multimedia Database Management System for Alzheimer's Disease Patients

    E-Print Network [OSTI]

    Stanchev, Peter

    to serve as a resource for the pediatric neuroimaging research community [6], (2) Brigham RAD Teaching Case Database Department of Radiology, Brigham and Women's Hospital Harvard Medical School [2], (3) Brain Web

  8. Integrated Molecular Signature of Disease: Analysis of Influenza...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of Disease: Analysis of Influenza Virus-Infected Macaques through Functional Genomics and Integrated Molecular Signature of Disease: Analysis of Influenza Virus-Infected...

  9. The Seattle Structure Genomics Center for Infectious Disease...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The Seattle Structure Genomics Center for Infectious Disease (SSGCID). The Seattle Structure Genomics Center for Infectious Disease (SSGCID). Abstract: The NIAID-funded Seattle...

  10. Structural genomics of infectious disease drug targets: the SSGCID...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of infectious disease drug targets: the SSGCID. Structural genomics of infectious disease drug targets: the SSGCID. Abstract: The NIAID-funded SSGCID is a consortium established to...

  11. alzheimers disease amyloid: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Alzheimer???s Disease Medications. Open Access Theses and Dissertations Summary: ??The brain of Alzheimer???s disease (AD) is characterized by accumulations of ??-amyloid peptide...

  12. alzheimer disease amyloid: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Alzheimer???s Disease Medications. Open Access Theses and Dissertations Summary: ??The brain of Alzheimer???s disease (AD) is characterized by accumulations of ??-amyloid peptide...

  13. Commercial Pecans: Controlling Rosette, Diseases and Zinc Deficiency

    E-Print Network [OSTI]

    Lee, Thomas A.; Krausz, Joseph P.

    2006-04-13T23:59:59.000Z

    Pecan losses from diseases and insufficient zinc nutrition can be prevented by following effective grove management practices. Descriptions of diseases and recommendations for controls are included....

  14. alzheimer's disease: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and memory deterioration, a clinical hallmark of Alzheimer's disease that the primary factor in the pathogenesis of cognitive de ciencies in Alzheimer's disease is the...

  15. anthracnose disease caused: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    disease of papaya Babak Madani a,*, Mahmud Tengku Muda Mohamed a,**, Alan R. Biggs c , Jugah Kadir October 2013 Keywords: Papaya Anthracnose Calcium Disease incidence...

  16. adult celiac disease: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Websites Summary: with a dietitian or physician who specializes in celiac disease. People with celiac disease should always read food for Celiac Awareness; Cynthia Kupper,...

  17. ASSISTANT/ASSOCIATE/FULL PROFESSOR Diabetes, Obesity, Metabolic Disease

    E-Print Network [OSTI]

    Cinabro, David

    ASSISTANT/ASSOCIATE/FULL PROFESSOR Diabetes, Obesity, Metabolic Disease Department strengths in diabetes, obesity and metabolic disease. Outstanding candidates with expertise

  18. A Systems Biology Approach to Infectious Disease Research: Innovating...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Systems Biology Approach to Infectious Disease Research: Innovating the Pathogen-Host Research Paradigm. A Systems Biology Approach to Infectious Disease Research: Innovating the...

  19. Restoration of Endangered White Abalone, Haliotis sorenseni: Resource Assessment, Genetics, Disease and Culture of Captive Abalone

    E-Print Network [OSTI]

    Burton, Ronald S.; McCormick, Thomas B.; Moore, James D.; Friedman, Carolyn S.

    2008-01-01T23:59:59.000Z

    Haliotis sorenseni: Resource Assessment, Genetics, Disease,Haliotis sorenseni: Resource Assessment, Genetics, Disease,Haliotis sorenseni: Resource Assessment, Genetics, Disease,

  20. Chronic cadmium exposure in vitro induces cancer cell characteristics in human lung cells

    SciTech Connect (OSTI)

    Person, Rachel J.; Tokar, Erik J.; Xu, Yuanyuan; Orihuela, Ruben; Ngalame, Ntube N. Olive; Waalkes, Michael P., E-mail: waalkes@niehs.nih.gov

    2013-12-01T23:59:59.000Z

    Cadmium is a known human lung carcinogen. Here, we attempt to develop an in vitro model of cadmium-induced human lung carcinogenesis by chronically exposing the peripheral lung epithelia cell line, HPL-1D, to a low level of cadmium. Cells were chronically exposed to 5 ?M cadmium, a noncytotoxic level, and monitored for acquired cancer characteristics. By 20 weeks of continuous cadmium exposure, these chronic cadmium treated lung (CCT-LC) cells showed marked increases in secreted MMP-2 activity (3.5-fold), invasion (3.4-fold), and colony formation in soft agar (2-fold). CCT-LC cells were hyperproliferative, grew well in serum-free media, and overexpressed cyclin D1. The CCT-LC cells also showed decreased expression of the tumor suppressor genes p16 and SLC38A3 at the protein levels. Also consistent with an acquired cancer cell phenotype, CCT-LC cells showed increased expression of the oncoproteins K-RAS and N-RAS as well as the epithelial-to-mesenchymal transition marker protein Vimentin. Metallothionein (MT) expression is increased by cadmium, and is typically overexpressed in human lung cancers. The major MT isoforms, MT-1A and MT-2A were elevated in CCT-LC cells. Oxidant adaptive response genes HO-1 and HIF-1A were also activated in CCT-LC cells. Expression of the metal transport genes ZNT-1, ZNT-5, and ZIP-8 increased in CCT-LC cells culminating in reduced cadmium accumulation, suggesting adaptation to the metal. Overall, these data suggest that exposure of human lung epithelial cells to cadmium causes acquisition of cancer cell characteristics. Furthermore, transformation occurs despite the cell's ability to adapt to chronic cadmium exposure. - Highlights: • Chronic cadmium exposure induces cancer cell characteristics in human lung cells. • This provides an in vitro model of cadmium-induced human lung cell transformation. • This occurred with general and lung specific changes typical for cancer cells. • These findings add insight to the relationship between cadmium and lung cancer.

  1. Potential role of differential medication use in explaining excess risk of cardiovascular events and death associated with chronic kidney disease: a cohort study

    E-Print Network [OSTI]

    2011-01-01T23:59:59.000Z

    N = 446 percutaneous coronary intervention, N = 260 cor-8.87 to 10.34) Percutaneous coronary intervention 4.25 (3.17outcomes among percutaneous coronary intervention patients

  2. 8th International Symposium on Growth and Nutrition in Children with Chronic Renal Disease: 28–30 May 2009, Oviedo, Asturias, Spain

    E-Print Network [OSTI]

    Santos, Fernando; Kaskel, Frederick J.; Mak, Robert H.; Caldas, Alberto

    2010-01-01T23:59:59.000Z

    2009, Oviedo, Asturias, Spain Fernando Santos & Frederick J.of Oviedo, Oviedo, Asturias, Spain F. J. Kaskel Montefiores/n, 33006 Oviedo, Asturias, Spain e-mail: fsantos@uniovi.es

  3. Asthma is a widespread public health problem that has continued to increase in Texas and nationwide. In Texas, asthma affects more children than any other chronic disease and

    E-Print Network [OSTI]

    . This pilot project is being funded by Region 6, Environmental Protection Agency (EPA). Your part risk in homes, and strategies on how families can reduce or even remove these triggers or risks from assessment of their home's indoor environment to identify potential triggers and lead risks. These same

  4. Bridging the Gap between Food Safety and Quality: Context and Potential Effects of Chronic Disease on Foodborne Illness and Health Outcomes

    E-Print Network [OSTI]

    Cummings, Patricia

    2014-01-01T23:59:59.000Z

    in LA County Food Services Contracts March 22, 2011. Motiona condi- tion for food service contract execution. 9,12 In

  5. Monitoring for Chronic Wasting Disease in Mule Deer and White-tailed Deer at Wind Cave National Park: Investigating an Emerging Epizootic

    E-Print Network [OSTI]

    was now part of a larger scientific family tree that included some rather prominent people in wildlife will try to be brief with the rest. I would like to thank my committee members: Dr. R. Terry Bowyer, Idaho State University. Terry was an inspiration in productivity and scientific rigor. He provided support

  6. Major prime contractors have developed a plan to address Hanford Beryllium exposure and are continuing to improve the Chronic Beryllium Disease Prevention Plan (CBDPP)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: VegetationEquipment Surfaces and InterfacesAdministration -Lowellfor 2013 |Spherical

  7. Everyday Healthy Living Do you or someone in your family live with a chronic

    E-Print Network [OSTI]

    Hardy, Christopher R.

    diseases--such as heart disease, stroke, cancer, diabetes, asthma, and arthritis--are among the most common your risk of diabetes, heart attack, stroke, or cancer by 80% if you would just do 4 things: Engage have because your father had a heart attack at age 48 and your grandmother's history of diabetes. You

  8. E-Print Network 3.0 - adults cardiovascular disease Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    disease, the number one killer of all Americans. Cardiovascular disease, or heart disease is the primary cause Summary: Kidney disease is both a cause and a consequence...

  9. E-Print Network 3.0 - affect cardiovascular disease Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    disease, the number one killer of all Americans. Cardiovascular disease, or heart disease is the primary cause Summary: Kidney disease is both a cause and a consequence...

  10. E-Print Network 3.0 - addressing cardiovascular disease Sample...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    disease, the number one killer of all Americans. Cardiovascular disease, or heart disease is the primary cause Summary: Kidney disease is both a cause and a consequence...

  11. Compensatory mechanisms in fish populations: Literature reviews: Volume 1, Critical evaluation of case histories of fish populations experiencing chronic exploitation or impact: Final report

    SciTech Connect (OSTI)

    Saila, S.B.; Chen, X.; Erzini, K.; Martin, B.

    1987-05-01T23:59:59.000Z

    This study includes case histories of certain fish species which are experiencing chronic perturbations and related literature pertaining to compensation processes. ''Compensation'' has been defined as the ability of fish to offset the population reduction caused by natural or man-induced stresses. Certain compensation methods are widely accepted, and include cannibalism, competition, disease, growth and predation, among others. These compensation methods are examined in relation to each fish species included in the study. Stock-recruit relationships and empirical observations of changes in growth and mortality have been the focus of much of the background on compensation. One of the conclusions drawn from this study is that a significant amount of recruitment variability exists and can be attributed to environmental (rather than compensatory) factors. The stock-recruitment problem appears to be the most significant scientific problem related to compensation in the types of fish included in this study. Results of the most recent studies of the American shad support this theory. Life histories, breeding biology and other pertinent data relating to each species included in the study will be found in the appendices.

  12. Physical Activity and Insulin Sensitivity. The RISC Study

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    for Diabetes, Obesity and Chronic Diseases, Geneva University Hospital, CH-1211 Geneva, Switzerland (Dr Golay-3Jul2008 Author manuscript, published in "Diabetes 57 (2008) 2613-2618" DOI : 10.2337/db07-1605 #12;Abstract OBJECTIVE--Physical activity is a modifiable risk factor for type 2 diabetes, partly through its

  13. The challenge of staphylococcal pacemaker endocarditis in a patient with transposition of the great arteries endocarditis in congenital heart disease

    SciTech Connect (OSTI)

    Ch'ng, Julie; Chan, William; Lee, Paul; Joshi, Subodh; Grigg, Leanne E.; Ajani, Andrew E

    2003-06-01T23:59:59.000Z

    Staphylococcus aureus is a leading cause of septicaemia and infective endocarditis. The overall incidence of staphylococcal bacteraemia is increasing, contributing to 16% of all hospital-acquired bacteraemias. The use of cardiac pacemakers has revolutionized the management of rhythm disturbances, yet this has also resulted in a group of patients at risk of pacemaker lead endocarditis and seeding in the range of 1% to 7%. We describe a 26-year-old man with transposition of the great arteries who had a pacemaker implanted and presented with S. aureus septicaemia 2 years postpacemaker implantation and went on to develop pacemaker lead endocarditis. This report illustrates the risk of endocarditis in the population with congenital heart disease and an intracardiac device.

  14. HORTICULTURAL & FOREST CROPS 2014 Nursery Crops: Diseases 4-1

    E-Print Network [OSTI]

    Liskiewicz, Maciej

    chemicals available. Only chemicals registered by the Environmental Protection Agency (EPA) are recommended.1 - Common Diseases and Chemical Control Options Plant Disease Fungicide Rate/100 Gal Remarks Ajuga;HORTICULTURAL & FOREST CROPS 2014 4-2 Nursery Crops: Diseases Table 4.1 - Common Diseases and Chemical Control

  15. The effect of dietary supplements on chronic bitterweed (Hymenoxys odorata) poisoning in sheep

    E-Print Network [OSTI]

    Post, Lynn Omer

    1982-01-01T23:59:59.000Z

    by experiment one. All animals were fed pelleted diets. b Animal Procurement and Care Thirty five Rambouillet cross sheep, about 2. 5 years of mixed sex and average weight of 40 kg, were housed on a covered concrete floor with water offered ad libitum...THE EFFECT OF DIETARY SUPPLEMENTS ON CHRONIC BITTERWEED (HYMENOXYS ODORATA) POISONING IN SHEEP A Thesis by LYNN OMER POST Submitted to the Graduate College of Texas A8M University in partial fulfillment of the requirement for the degree...

  16. Protease Inhibition by Oleic Acid Transfer From Chronic Wound Dressings to Albumin

    SciTech Connect (OSTI)

    Edwards, J. V.; Howley, Phyllis; Davis, Rachel M.; Mashchak, Andrew D.; Goheen, Steven C.

    2007-08-01T23:59:59.000Z

    High elastase and cathepsin G activities have been observed in chronic wounds. These levels can inhibit healing through degradation of growth factors, cytokines, and extracellular matrix proteins. Oleic acid (18:1) is a non-toxic elastase inhibitor with some potential for redressing the imbalance of elastase activity found in chronic wounds. Cotton wound dressing material was characterized as a transfer carrier for affinity uptake of 18:1 by albumin under conditions mimicking chronic wounds. 18:1-treated cotton was examined for its ability to bind and release the fatty acid in the presence of albumin. The mechanism of 18:1 uptake from cotton and binding by albumin was examined with both intact dressings and cotton fiber-designed chromatography. Raman spectra of the albumin-18:1 complexes under liquid-liquid equilibrium conditions revealed fully saturated albumin-18:1 complexes with a 1:1 weight ratio of albumin:18:1. Cotton chromatography under liquid-solid equilibrium conditions revealed oleic acid transfer from cotton to albumin at 27 mole equivalents of 18:1 per mole albumin. Cotton was contrasted with hydrogel, and hydrocolloid wound dressing for its comparative ability to lower elastase activity. Each dressing material evaluated was found to release 18:1 in the presence of albumin with significant inhibition of elastase activity. The 18:1-formulated wound dressings lowered elastase activity in a dose dependent manner in the order cotton gauze > hydrogel > hydrocolloid. In contrast the cationic serine protease Cathepsin G was inihibited by 18:1 within a narrow range of 18:1-cotton formulations. Four per cent Albumin solutions were most effective in binding cotton bound-18:1. However, 2% albumin was sufficient to transfer quantities of 18:1 necessary to achieve a significant elastase-lowering effect. Formulations with 128 mg 18:1/g cotton gauze had equivalent elastase lowering with 1 - 4% albumin. 18:1 bound to cotton wound dressings may have promise in the selective lowering of cationic serine protease activity useful in topical application for chronic inflammatory pathogenesis.

  17. Effect of chronic exposure to low levels of ethylene on cotton during germination and early development

    E-Print Network [OSTI]

    Cowan, Elaine Nan

    1979-01-01T23:59:59.000Z

    for the degree of NASTER OF SCIENCE Auoust 1979 . "iajor Subject: Plant Physiology THE EFFECT OF CHRONIC EXPOSURE TO LON LEVELS OF ETHYLENE ON COTTON DURING GERMINATION AND EARLY DEVELOPMENT A Thesis by ELAINF NAN CONAN Approved as to sty1e and content... and Ryan indicated that endopeptidase reached a peak in activity 10 days after planting. Fumigation with 0. 5 ul/1 ethylene for 5 days prior to harvest inhibited this in- crease in activity. The present study was undertaken to deter- mine...

  18. Associations between pain intensity, functional status, and beliefs and attitudes towards pain in people with chronic pain, after a lidocaine infusion.

    E-Print Network [OSTI]

    Masse, Julie.

    2009-01-01T23:59:59.000Z

    ??BACKGROUND: Pain intensity, functional status and beliefs and attitudes towards pain are dynamic elements involved in the experience of chronic pain. Lidocaine infusion (LI) is… (more)

  19. A medium-rise 1970’s maternity hospital in the east of England: resilience and adaptation to climate change

    E-Print Network [OSTI]

    Short, C. Alan; Giridharan, Renganathan; Lomas, Kevin J.

    2014-01-01T23:59:59.000Z

    .Thomas’s tower on the Thames and Oxford’s John Radcliffe Hospital. The essential framed, glazed treatment is consistent. Writing particularly of F.R.S.Yorke, YRM’S founder and an important publicist for modern architecture, Worsley wrote,” it was the rise... a huge barrier to achieving adaptation of the public non-domestic building stock, unfortunate given that the NHS Retained Estate would seem to be a particularly promising place to implement a public sector adaptation scheme...

  20. Mouse and human embryonic stem cells: can they improve human health by preventing disease?

    E-Print Network [OSTI]

    Talbot, Prue

    2013-01-01T23:59:59.000Z

    diseases, they also have equally great potential to prevent disease by identifying dangerous environmental chemicals

  1. Purdue Extension Muskmelon and Watermelon Diseases

    E-Print Network [OSTI]

    to muskmelons than watermelons. The disease is caused by a fungus (Alternaria cucumerina) that can rapidly Conditions · A brief introduction to the Melcast concept. III. Using Melcast · Acquiring Environmental Data - A description of data requirements for running Melcast. · Translating Environmental Data into EFI Values

  2. Vaccine approaches with Edinburgh Infectious Diseases

    E-Print Network [OSTI]

    Maizels, Rick

    Vaccine approaches with Edinburgh Infectious Diseases Alexander Corbishley #12;The technology approaches to knowledge exchange · October 2013: three technology scouts seconded for 12 months, to identify Congress 2014 (Washington DC) · Local partnering meetings with SMEs · Discussions with Open Innovation

  3. Osteoporosis Osteoporosis is a disease character-

    E-Print Network [OSTI]

    SS-167-R05 Osteoporosis Osteoporosis is a disease character- ized by structural deterioration of bone tissue, leading to fragile bones and low bone mass. Osteoporosis can weaken bones and cause them" because bone loss occurs with- out symptoms. Many people may not know that they have osteoporosis until

  4. DISEASES OF AQUATIC ORGANISMS Dis Aquat Org

    E-Print Network [OSTI]

    Nizet, Victor

    ), and hybrid striped bass (Evans et al. 2000). Clinical symptoms of S. iniae infection in fish include loss from the freshwater dolphin Inia geoffrensis (Pier & Madin 1976), S. iniae infects a wide range of fish infection in humans who have handled diseased fish (Weinstein et al. 1997). Despite the need for novel

  5. Northern Kentucky University Communicable Disease Protocol

    E-Print Network [OSTI]

    Boyce, Richard L.

    Northern Kentucky University Communicable Disease Protocol Approved 12/6/2011 1.0 Scope To develop procedures and policies for Northern Kentucky University students who reside on or off- campus who have been those required as outlined in 902 KAR 2:020 to be reported to the Northern Kentucky Health Department

  6. Disease Prediction Models and Operational Readiness

    SciTech Connect (OSTI)

    Corley, Courtney D.; Pullum, Laura L.; Hartley, David M.; Benedum, Corey M.; Noonan, Christine F.; Rabinowitz, Peter M.; Lancaster, Mary J.

    2014-03-19T23:59:59.000Z

    INTRODUCTION: The objective of this manuscript is to present a systematic review of biosurveillance models that operate on select agents and can forecast the occurrence of a disease event. One of the primary goals of this research was to characterize the viability of biosurveillance models to provide operationally relevant information for decision makers to identify areas for future research. Two critical characteristics differentiate this work from other infectious disease modeling reviews. First, we reviewed models that attempted to predict the disease event, not merely its transmission dynamics. Second, we considered models involving pathogens of concern as determined by the US National Select Agent Registry (as of June 2011). Methods: We searched dozens of commercial and government databases and harvested Google search results for eligible models utilizing terms and phrases provided by public health analysts relating to biosurveillance, remote sensing, risk assessments, spatial epidemiology, and ecological niche-modeling, The publication date of search results returned are bound by the dates of coverage of each database and the date in which the search was performed, however all searching was completed by December 31, 2010. This returned 13,767 webpages and 12,152 citations. After de-duplication and removal of extraneous material, a core collection of 6,503 items was established and these publications along with their abstracts are presented in a semantic wiki at http://BioCat.pnnl.gov. Next, PNNL’s IN-SPIRE visual analytics software was used to cross-correlate these publications with the definition for a biosurveillance model resulting in the selection of 54 documents that matched the criteria resulting Ten of these documents, However, dealt purely with disease spread models, inactivation of bacteria, or the modeling of human immune system responses to pathogens rather than predicting disease events. As a result, we systematically reviewed 44 papers and the results are presented in this analysis.

  7. Surgical, pathological and clinical correlation of Tc-99m DISIDA hepatobiliary imaging in 138 adult males, in the diagnosis of functional cystic duct obstruction VS acute or chronic cholecystitis

    SciTech Connect (OSTI)

    Yoo, J.H.K.; Beal, W.H.; Ware, R.W.; Straw, J.D.; Chaudhuri, T.K.

    1985-05-01T23:59:59.000Z

    Despite the wide acceptance of the hepatobiliary scintigraphy as a popular diagnostic imaging modality for gallbladder and hepatobiliary disease, correlation between radionuclide diagnoses and the final clinical and/or pathologic findings have not been thoroughly evaluated. The lack of correlative studies frequently generates difficulties in making appropriate diagnostic interpretation of the objective findings. A retrospective clinical pathological and surgical correlative study was undertaken by the authors in 138 male veteran patients, who underwent computer assisted minute by minute Tc-99m DISIDA cholescintigraphy. A very high percentage (75%) revealed abnormalities; non-visualization of gallbladder (GB) with normal choledochus system (46%), choledochal obstruction with no GB visualization (13%), choledochal obstruction with normal GB visualization (6%), severe hepatocellular disease with non-diagnostic GB (4%), and delayed GB visualization (longer than 60 minutes) (3%). Non-visualization of GB but normal choledochus demonstrated diverse pathologic etiologies, acute and chronic cholecystitis (64%), S/P cholecystectomy (8%), functional obstruction secondary to sepsis or pancreatitis (6%), and various other pathologies including porcelain GB and cholangitis (22%). The most important cause of choledochal obstruction was mass lesions or local infiltration with metastases (33%) rather than acute cholecystitis (27%). Although the sensitivity (98%) and specificity (92%) for cystic duct obstruction were very high, the specificity decreases significantly for cholecystitis.

  8. Activation of retinal tyrosine hydroxylase: tolerance induced by chronic treatment with haloperidol does not modify response to light

    SciTech Connect (OSTI)

    Cohen, J.; Neff, N.H.

    1982-05-01T23:59:59.000Z

    A single dose of haloperidol administered to rats in the dark increases the activity of retinal tyrosine hydroxylase. The ability of haloperidol to activate the enzyme is diminished 24 hr after terminating 22 to 30 days of treatment with haloperidol. The retinal enzyme is also tolerant to activation by treatment with chlorpromazine. In contrast, exposure of the animals to light activates the enzyme to the same extent in chronic haloperidol-treated and control animals. Thus, chronic haloperidol treatment does not modify the ability of the retinal enzyme system to respond to the physiological stimulus, light. Apparently, activation of retinol tyrosine hydroxylase by haloperidol and light occurs by independent mechanisms.

  9. Poultry Diseases Expert System using Dempster-Shafer Theory

    E-Print Network [OSTI]

    Maseleno, Andino

    2012-01-01T23:59:59.000Z

    Based on World Health Organization (WHO) fact sheet in the 2011, outbreaks of poultry diseases especially Avian Influenza in poultry may raise global public health concerns due to their effect on poultry populations, their potential to cause serious disease in people, and their pandemic potential. In this research, we built a Poultry Diseases Expert System using Dempster-Shafer Theory. In this Poultry Diseases Expert System We describe five symptoms which include depression, combs, wattle, bluish face region, swollen face region, narrowness of eyes, and balance disorders. The result of the research is that Poultry Diseases Expert System has been successfully identifying poultry diseases.

  10. Biomonitoring of organochlorines in women with benign and malignant breast disease

    SciTech Connect (OSTI)

    Siddiqui, M.K.J. [Analytical Toxicology, Industrial Toxicology Research Centre, P.O. Box No. 80, M.G. Marg, Lucknow 226 001 (India)]. E-mail: mkjs@rediffmail.com; Anand, M. [Analytical Toxicology, Industrial Toxicology Research Centre, P.O. Box No. 80, M.G. Marg, Lucknow 226 001 (India); Mehrotra, P.K. [Sir Ganga Ram Hospital, New Delhi (India); Sarangi, R. [Sir Ganga Ram Hospital, New Delhi (India); Mathur, N. [Analytical Toxicology, Industrial Toxicology Research Centre, P.O. Box No. 80, M.G. Marg, Lucknow 226 001 (India)

    2005-06-01T23:59:59.000Z

    Established risk factors for breast cancer explain breast cancer risk only partially. Organochlorines are considered to be a possible cause for hormone-dependent cancers. A hospital-based case-control study, the first from India, was conducted among 50 women undergoing surgery for breast disease to examine the association between organochlorine exposure and breast cancer risk. Blood, tumor, and surrounding adipose tissue of the breast were collected from the subjects with benign (control) and malignant breast (study) lesions and analyzed to determine organochlorine insecticides using a gas-liquid chromatograph equipped with an electron capture detector. The {alpha}, {beta}, {gamma}, and {delta} isomers of hexachlorocyclohexane (HCH), p,p'-dichlorodiphenyltrichloroethane (DDT), o,p'-DDT, p,p-dichlorodiphenyldichloroethylene, and p,p'-dichlorodiphenyldichloroethane were frequently detected in three specimens. Total HCH and total DDT levels were higher in the blood of the study group (25 cases) than in those of the controls (25 cases) with only {gamma}-HCH being significantly different (P0.05). However, both total HCH and total DDT were higher in the tumor tissues of the controls than in those of the study group; {gamma}-HCH was significantly different (P0.05). The level of total HCH ({alpha}-HCH was significantly different, P0.05) was higher in the breast adipose tissue of the study group, whereas total DDT was higher in the breast adipose tissue of the control group. The distribution of known confounders of breast cancer including age, body mass index, age at menarche and menopause, duration of breast feeding, and family history related to breast disease did not differ significantly between benign and malignant groups. This pilot study with limited statistical power does not support a positive association between exposure to organochlorines and risk of breast cancer but paves the way for a larger Indian study with greater statistical power encompassing different regions of the country to enable statistically sound conclusions.

  11. Risk of Chronic Oral Anticoagulation Therapy in Patients Undergoing Primary Percutaneous Coronary Intervention for ST Elevation Myocardial Infarction - Retrospective Cross-Sectional Study

    E-Print Network [OSTI]

    Vanga, Subba Reddy

    2013-12-31T23:59:59.000Z

    i Risk of Chronic Oral Anticoagulation Therapy in Patients Undergoing Primary Percutaneous Coronary Intervention for ST Elevation Myocardial Infarction – Retrospective Cross-Sectional Study BY Copyright 2013 Subba Reddy Vanga... The Thesis Committee for Subba Reddy Vanga certifies that this is the approved version of the following thesis: Risk of Chronic Oral Anticoagulation Therapy in Patients Undergoing Primary Percutaneous Coronary Intervention for ST Elevation...

  12. Texas Plant Disease Diagnostic Lab Information Form

    E-Print Network [OSTI]

    Barnes, Larry W.

    2009-01-16T23:59:59.000Z

    TEXAS PLANT DISEASE DIAGNOSTIC LABORATORY 1500 Research Parkway, Suite A130 Texas A&M University Research Park College Station, Texas 77845 e-mail: plantclinic@ag.tamu.edu phone: 979.845.8032 fax: 979.845.6499 http..., disability, religion, age, or national origin. The Texas A&M System, U.S. Department of Agriculture, and the County Commissioners Courts of Texas cooperating. Please complete form for diagnostic services. Please PRINT and mark ? all that apply. PLANT...

  13. Women and Heart Disease: Neglected Directions for Future Research

    E-Print Network [OSTI]

    Barrett-Connor, Elizabeth

    2009-01-01T23:59:59.000Z

    009-9110-0 Women and Heart Disease: Neglected Directions forage 65, women have less heart disease than men. For many1980s showed a lower risk of heart attacks in postmenopausal

  14. alberta kidney disease: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    for nearly 44 percent of new cases.1 Even when diabetes is controlled, the disease can lead to CKD Baker, Chris I. 2 Kidney Dysplasia National Kidney and Urologic Diseases...

  15. animal virus diseases: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Physics Websites Summary: Modelling the spread of foot-and-mouth disease virus F Moutou B Durand CNEVA, Laboratoire Central-and-mouth disease is an economically important viral...

  16. animal disease models: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Physics Websites Summary: Modelling the spread of foot-and-mouth disease virus F Moutou B Durand CNEVA, Laboratoire Central-and-mouth disease is an economically important viral...

  17. Characterization of a Drosophila model of Huntington's disease

    E-Print Network [OSTI]

    Lee, Wyan-Ching Mimi

    2006-01-01T23:59:59.000Z

    Huntington's disease (HD) is an autosomal dominant neurological disorder caused by a polyglutamine (polyQ) repeat expansion in the huntingtin (Htt) protein. The disease is characterized by neurodegeneration and formation ...

  18. Annular lichen planus in association with Crohn disease

    E-Print Network [OSTI]

    Serrão, Vasco Vieira; Organ, Vasili; Pereira, Luís; Vale, Esmeralda; Correia, Suzete

    2008-01-01T23:59:59.000Z

    of Crohn disease and a sickle cell trait. Therapy withparasites were excluded. Sickle cell trait was diagnosed (

  19. Magnetic Resonance Imaging-Guided Osseous Biopsy in Children With Chronic Recurrent Multifocal Osteomyelitis

    SciTech Connect (OSTI)

    Fritz, Jan, E-mail: jfritz9@jhmi.edu [Johns Hopkins University School of Medicine, Russell H. Morgan Department of Radiology and Radiological Science (United States); Tzaribachev, Nikolay [University Children's Hospital, Eberhard-Karls-University Tuebingen, Division of Pediatric Rheumatology (Germany); Thomas, Christoph [Eberhard-Karls-University Tuebingen, Department of Diagnostic and Interventional Radiology (Germany); Wehrmann, Manfred [Eberhard-Karls-University Tuebingen, Department of Pathology (Germany); Horger, Marius S. [Eberhard-Karls-University Tuebingen, Department of Diagnostic and Interventional Radiology (Germany); Carrino, John A. [Johns Hopkins University School of Medicine, Russell H. Morgan Department of Radiology and Radiological Science (United States); Koenig, Claudius W.; Pereira, Philippe L. [Eberhard-Karls-University Tuebingen, Department of Diagnostic and Interventional Radiology (Germany)

    2012-02-15T23:59:59.000Z

    Purpose: To report the safety and diagnostic performance of magnetic resonance (MRI)-guided core biopsy of osseous lesions in children with chronic recurrent multifocal osteomyelitis (CRMO) that were visible on MRI but were occult on radiography and computed tomography (CT). Materials and Methods: A retrospective analysis of MRI-guided osseous biopsy performed in seven children (four girls and three boys; mean age 13 years (range 11 to 14) with CRMO was performed. Indication for using MRI guidance was visibility of lesions by MRI only. MRI-guided procedures were performed with 0.2-Tesla (Magnetom Concerto; Siemens, Erlangen, Germany; n = 5) or 1.5-T (Magnetom Espree; Siemens; n = 2) open MRI systems. Core needle biopsy was obtained using an MRI-compatible 4-mm drill system. Conscious sedation or general anesthesia was used. Parameters evaluated were lesion visibility, technical success, procedure time, complications and microbiology, cytology, and histopathology findings. Results: Seven of seven (100%) targeted lesions were successfully visualized and sampled. All obtained specimens were sufficient for histopathological analysis. Length of time of the procedures was 77 min (range 64 to 107). No complications occurred. Histopathology showed no evidence of malignancy, which was confirmed at mean follow-up of 50 months (range 28 to 78). Chronic nonspecific inflammation characteristic for CRMO was present in four of seven (58%) patients, and edema with no inflammatory cells was found in three of seven (42%) patients. There was no evidence of infection in any patient. Conclusion: MRI-guided osseous biopsy is a safe and accurate technique for the diagnosis of pediatric CRMO lesions that are visible on MRI only.

  20. 1. Coastal waters are often exposed to heavy metals (HM) introduced from point and diffusive sources. Chronic and

    E-Print Network [OSTI]

    Einat, Aharonov

    1. Coastal waters are often exposed to heavy metals (HM) introduced from point and diffusive higher than in sea water. Heavy metals concentration in seawater 4. Most of the dissolved heavy metals sources. Chronic and acute environmental criteria for water quality were developed (e.g. EPA) based

  1. EFFECTS OF CHRONIC COPPER EXPOSURE ON DEVELOPMENT AND SURVIVAL IN THE SOUTHERN LEOPARD FROG (LITHOBATES [RANA] SPHENOCEPHALUS)

    E-Print Network [OSTI]

    Georgia, University of

    EFFECTS OF CHRONIC COPPER EXPOSURE ON DEVELOPMENT AND SURVIVAL IN THE SOUTHERN LEOPARD FROG, substantially less is known concerning the potential effects of metals on amphibian populations. Copper (Cu;31:1587­1594. # 2012 SETAC Keywords--Lithobates (Rana) sphenocephalus Copper Amphibian Ecotoxicology Metal toxicity

  2. A Century of Progress: Milestones in Sickle Cell Disease

    E-Print Network [OSTI]

    Bandettini, Peter A.

    A Century of Progress: Milestones in Sickle Cell Disease Research and Care Introduction In 1910 to be known as sickle cell disease. One hundred years later we know that the sickle-shaped cells are due take the characteristic "C"-shape that is the hallmark of sickle cell disease. What is Sickle Cell

  3. Harvesting can increase severity of wildlife disease epidemics

    E-Print Network [OSTI]

    Harvesting can increase severity of wildlife disease epidemics Marc Choisy1,* and Pejman Rohani1 extinction. Surprisingly, infectious diseases have not been accounted for in harvest models, which is a major and harvesting can substantially increase both disease prevalence and the absolute number of infectious

  4. PRINCIPAL DISEASES OF COMMERCIALLY IMPORTANT MARINE BIVALVE MOLLUSCA AND CRUSTACEA

    E-Print Network [OSTI]

    of disease-resistant strains of shellfish, environmental manipulation (dredging of grow. ing areas, chemical has ex- panded, it has become evident that disease, among other environmental variables, can drasPRINCIPAL DISEASES OF COMMERCIALLY IMPORTANT MARINE BIVALVE MOLLUSCA AND CRUSTACEA By Carl J

  5. Using “warm handoffs” to link hospitalized smokers with tobacco treatment after discharge: study protocol of a randomized controlled trial

    E-Print Network [OSTI]

    Faseru, Babalola; Mussulman, Laura M.; Ellerbeck, Edward F.; Shireman, Theresa I.; Hunt, Jamie J.; Carlini, Beatriz H.; Preacher, Kristopher J.; Ayars, Candace L.; Cook, David J.; Richter, Kimber P.

    2012-08-01T23:59:59.000Z

    post-randomization Handoff Figure 1 Overview and study design of EQUIP – a randomized controlled trial.will collect 1-, 6-, and 12-month follow-up data. Outcome measures and analyses include 30-day point prevalence abstinence at 6 months, biochemically...:10.1186/1745-6215-13-127 Cite this article as: Richter et al.: Using “warm handoffs” to link hospitalized smokers with tobacco treatment after discharge: study protocol of a randomized controlled trial. Trials 2012 13:127. Richter et al. Trials 2012...

  6. Comparison of LEED to Non-LEED Certified Hospitals with Regards to Patient Perspective and Financial Indicators

    E-Print Network [OSTI]

    Ulusoy, Eren

    2012-10-19T23:59:59.000Z

    , which leads to global warming (Joseph et al. 2010). In 2003, hospitals were making a 9 percent contribution to the total energy consumption in the U.S., a significant level of consumption when compared to the other sector (EIA 2011). Figure 1.1 shows... the rank of healthcare facilities with other building types regarding total amount of energy consumption. Figure 1.1 Energy Use by Type of Commercial Building, 2003(EIA 2011) ____________ This thesis follows the style of Journal of Construction...

  7. Neurobiology of Disease Neuroinflammation Alters the Hippocampal Pattern of

    E-Print Network [OSTI]

    Wenk, Gary

    chronically infused with lipopolysaccharide (LPS) (0.25 g/h) into the fourth ventricle for 28 d. On day 29 and CA3 regions of LPS-infused rats, Arc and OX-6 (specific for major histocompatibility complex class II immunoreactivity) and elevated exploration-induced Arc expression compared with control-infused rats. In contrast

  8. Disparities in Emergency Department Quality of Care among Patients with and without Coronary Heart Disease Diagnoses

    E-Print Network [OSTI]

    Sammartinova, Jitka

    2013-01-01T23:59:59.000Z

    coronary heart disease and heart attack, and perceive theyheart disease and heart attack, and tend to perceive thatfor heart disease and heart attack, and do not recognize

  9. Smoking and Ischemic Heart Disease Disparities Between Studies, Genders, Times, and Socioeconomic Strata

    E-Print Network [OSTI]

    Leistikow, Bruce N.

    2009-01-01T23:59:59.000Z

    predictors of coronary heart disease among women. Americanon the risk for coronary heart disease even stronger thanx Smoking and Ischemic Heart Disease Disparities Between

  10. E-Print Network 3.0 - acute diarrhoeal disease Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    (collectively) the diarrhoeal diseases. Each... .4. Diarrhoeal diseases 4.4.1. Deprive resources needed to fight disease The most common fatal complication... arising from...

  11. E-Print Network 3.0 - advanced eye disease Sample Search Results

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Safety PRogRam Summary: . Leptospirosis Leptospirosis is a bacterial disease that causes abortion, eye problems and kidney disease... Horse Transmitted DiseasesSaddle Up SAFELY...

  12. E-Print Network 3.0 - acute kawasaki disease Sample Search Results

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Nile Virus and Encephalitis; Kawasaki disease that may be transmitted by an unknown... problems. Vector borne diseases and Kawasaki Disease are two areas CAPCCCC are currently...

  13. Analysis of Dose Response for Circulatory Disease After Radiotherapy for Benign Disease

    SciTech Connect (OSTI)

    Little, Mark P., E-mail: mark.little@nih.gov [Radiation Epidemiology Branch, National Cancer Institute, Executive Plaza South, Rockville, Maryland (United States); Kleinerman, Ruth A. [Radiation Epidemiology Branch, National Cancer Institute, Executive Plaza South, Rockville, Maryland (United States)] [Radiation Epidemiology Branch, National Cancer Institute, Executive Plaza South, Rockville, Maryland (United States); Stovall, Marilyn; Smith, Susan A. [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States)] [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Mabuchi, Kiyohiko [Radiation Epidemiology Branch, National Cancer Institute, Executive Plaza South, Rockville, Maryland (United States)] [Radiation Epidemiology Branch, National Cancer Institute, Executive Plaza South, Rockville, Maryland (United States)

    2012-12-01T23:59:59.000Z

    Purpose: To assess the shape of the dose-response for various circulatory disease endpoints, and modifiers by age and time since exposure. Methods and Materials: This was an analysis of the US peptic ulcer data testing for heterogeneity of radiogenic risk by circulatory disease endpoint (ischemic heart, cerebrovascular, other circulatory disease). Results: There were significant excess risks for all circulatory disease, with an excess relative risk Gy{sup -1} of 0.082 (95% CI 0.031-0.140), and ischemic heart disease, with an excess relative risk Gy{sup -1} of 0.102 (95% CI 0.039-0.174) (both p = 0.01), and indications of excess risk for stroke. There were no statistically significant (p > 0.2) differences between risks by endpoint, and few indications of curvature in the dose-response. There were significant (p < 0.001) modifications of relative risk by time since exposure, the magnitude of which did not vary between endpoints (p > 0.2). Risk modifications were similar if analysis was restricted to patients receiving radiation, although the relative risks were slightly larger and the risk of stroke failed to be significant. The slopes of the dose-response were generally consistent with those observed in the Japanese atomic bomb survivors and in occupationally and medically exposed groups. Conclusions: There were excess risks for a variety of circulatory diseases in this dataset, with significant modification of risk by time since exposure. The consistency of the dose-response slopes with those observed in radiotherapeutically treated groups at much higher dose, as well as in lower dose-exposed cohorts such as the Japanese atomic bomb survivors and nuclear workers, implies that there may be little sparing effect of fractionation of dose or low-dose-rate exposure.

  14. A study of the pecan shuck disease

    E-Print Network [OSTI]

    Williams, James Mclaren

    1969-01-01T23:59:59.000Z

    29 Micro. 28 + Macro. 27 10 11 Cyprex 12 33 Mi cro . 34 + Zinc 35 36 37 Zinc 38 26 25 24 23 22 21 Micro. Cyprex + Macro. 13 Cyprex 14 + Micro. 15 16 Cyprex 17 + Zinc 18 0 I a 'o tU 4J m w 4J o 39 20 19... in the study of the effect of various treatments on the incidence of pecan shuck disease. 12 Fig. 3-3. John Bean sprayer used to make the foliar applications of zinc, Cyprex fungicide and microelements. A) Front view, B) Side view. 13 Table 3...

  15. Chemicals for Plant Disease Control at Home

    E-Print Network [OSTI]

    Ong, Kevin

    2007-10-30T23:59:59.000Z

    name/type Product name Brand T/O V F 1. biological Serenade Garden Disease Control Agraquest y y y 2. botanical Lawn & Turf Fungicide Garlic GP y n n E-rase RTU Monterey y y y Organic Rose & Flower Spray Greenlight y n n Paradigm Parkway Research y n n... product Oil and Lime Sulfur Bonide y n y 8. mancozeb Mancozeb Flowable Bonide y y n Dithane M-45 Southern Ag y y n 9. maneb Maneb Garden Fungicide Hi-Yield y y n 10. myclobutanil F-Stop Fertilome y n n Fung-Away Systemic Lawn Fungicide Granules Greenlight...

  16. E-Print Network 3.0 - acute marchiafava-bignami disease Sample...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The acute and chronic consequences... of hepatitis B virus infection are major health problems in the United States. The reported incidence of ... Source: Virginia Tech,...

  17. E-Print Network 3.0 - acute disease Sample Search Results

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The acute and chronic consequences... of hepatitis B virus infection are major health problems in the United States. The reported incidence of ... Source: Virginia Tech,...

  18. diseases based upon common toxicogenomic profiles at CTD

    E-Print Network [OSTI]

    Allan Peter Davis; Michael C. Rosenstein; Thomas Conrad Wiegers; Carolyn J. Mattingly

    2011-01-01T23:59:59.000Z

    The Comparative Toxicogenomics Database (CTD) is a free resource that describes chemical-gene-disease networks to help understand the effects of environmental exposures on human health. The database contains more than 13,500 chemical-disease and 14,200 gene-disease interactions. In CTD, chemicals and genes are associated with a disease via two types of relationships: as a biomarker or molecular mechanism for the disease (M-type) or as a real or putative therapy for the disease (T-type). We leveraged these curated datasets to compute similarity indices that can be used to produce lists of comparable diseases (“DiseaseComps”) based upon shared toxicogenomic profiles. This new metric now classifies diseases with common molecular characteristics, instead of the traditional approach of using histology or tissue of origin to define the disorder. In the dawning era of “personalized medicine”, this feature provides a new way to view and describe diseases and will help develop testable hypotheses about chemical-gene-disease networks. Availability: CTD is freely available at

  19. AFBC co-firing of coal and hospital waste. Quarterly progress report, February 1, 1995--April 30, 1995

    SciTech Connect (OSTI)

    Stuart, J.M.

    1996-01-01T23:59:59.000Z

    The project objective is to design, construct, install, provide operator training and start-up a circulating fluidized bed combustion system at the Lebanon Pennsylvania Veteran`s Affairs Medical Center. This unit will co-fire coal and hospital waste providing inexpensive and efficient destruction of both general and infectious hospital waste and steam generation. The steam generated is as follows: (1) Steam = 20,000 lb/hr, (2) Temperature = 353 F (saturated), (3) Pressure = 125 psig, and (4) Steam quality ={approximately}98.5%. On February 3, 1995 DONLEE notified Lebanon VA and DOE-METC that additional funding would be required to complete the project. This funding, in the amount of $1,140,127, is needed to complete the facility, start-up and shakedown the facility, perform the test program and write the final report. On March 7, 1995 the vendors were notified that the Lebanon VA Steam Plant Project was shut down and that all work outside DONLEE was stopped pending obtaining additional funding.

  20. AFBC co-firing of coal and hospital waste. Quarterly progress report, May 1--July 31, 1995

    SciTech Connect (OSTI)

    Stuart, J.M.

    1995-12-31T23:59:59.000Z

    The project objective is to design, construct, install, provide operator training and start-up a circulating fluidized bed combustion system at the Lebanon, Pennsylvania Veteran`s Affairs Medical Center. This unit will co-fire coal and hospital waste providing lower cost steam for heating and possibly cooling (absorption chiller) and operation of a steam turbine-generator for limited power generation. This would permit full capacity operation of the FBC year round in spite of the VA laundry that was shut down as well as efficient destruction of both general and infectious hospital waste and steam generation. On February 3, 1995 Donlee notified Lebanon VA and DOE-METC that additional funding would be required to complete the project. This funding, in the amount of $1,140,127, is needed to complete the facility, start-up and shakedown the facility, perform the test program and write the final report. After review DOE-METC approved funding in the amount of $1,246,019 to be available August 1, 1995. This report describes each task of the project and its status.

  1. Disparities in Emergency Department Quality of Care among Patients with and without Coronary Heart Disease Diagnoses

    E-Print Network [OSTI]

    Sammartinova, Jitka

    2013-01-01T23:59:59.000Z

    MM. Warning signs of a heart attack. Circulation. 2001;104:infarction. The Worcester Heart Attack Study. Arch. Intern.hospitalized with heart attack symptoms in the United

  2. Developing an indicator for the chronic health impact of traffic-related pollutant emissions

    SciTech Connect (OSTI)

    Lepicier, Veronique [IFSTTAR, Laboratoire Transport et Environnement, 25, av. F. Mitterrand, 69675 Bron Cedex (France); Chiron, Mireille [IFSTTAR, UMRESTTE, 25, av. F. Mitterrand, 69675 Bron Cedex (France); Joumard, Robert, E-mail: robert.joumard@laposte.net [IFSTTAR, Laboratoire Transport et Environnement, 25, av. F. Mitterrand, 69675 Bron Cedex (France)

    2013-01-15T23:59:59.000Z

    The goal of this study is to develop an emission based indicator for the health impact of the air pollution caused by traffic. This indicator must make it possible to compare different situations, for example different Urban Travel Plans, or technical innovations. Our work is based on a literature survey of methods for evaluating health impacts and, more particularly, those which relate to the atmospheric pollution caused by transport. We then define a health impact indicator based on the traffic emissions, named IISCEP for Chronic health impact indicator of pollutant emission. Here health is understood in a restricted meaning, excluding well-being. Only primary pollutants can be considered, as the inputs are emission data and an indicator must be simple. The indicator is calculated as the sum of each pollutant emission multiplied by a dispersion and exposition factor and a substance specific toxicity factor taking account of the severity. Last, two examples are shown using the IISCEP: comparison between petrol and diesel vehicles, and Nantes urban district in 2008 vs 2002. Even if it could still be improved, IISCEP is a straightforward indicator which can be used to gauge the chronic effects of inhaling primary pollutants. It can only be used in comparisons, between different scenarios or different technologies. The quality of the emissions data and the choice of the pollutants that are considered are the two essential factors that determine its validity and reliability. - Highlights: Black-Right-Pointing-Pointer The goal of the study is to develop an emission based indicator for the health impact of the air pollution caused by traffic. Black-Right-Pointing-Pointer It is based on a literature survey of methods for evaluating health impacts related to the atmospheric pollution. Black-Right-Pointing-Pointer We define a composite indicator based on the traffic emissions and on local data as dispersion conditions and population. Black-Right-Pointing-Pointer The indicator is a combination of pollutant emission, dispersion, exposition factor, and substance specific toxicity factor. Black-Right-Pointing-Pointer Applications are global (e.g. comparison of vehicle technologies) or local (e.g. comparison of populations or areas).

  3. Acute and chronic toxicity of uranium compounds to Ceriodaphnia-Daphnia dubia

    SciTech Connect (OSTI)

    Pickett, J.B.; Specht, W.L.; Keyes, J.L.

    1993-03-31T23:59:59.000Z

    A study to determine the acute and chronic toxicity of uranyl nitrate, hydrogen uranyl phosphate, and uranium dioxide to the organism Ceriodaphnia dubia was conducted. The toxicity tests were conducted by two independent environmental consulting laboratories. Part of the emphasis for this determination was based on concerns expressed by SCDHEC, which was concerned that a safety factor of 100 must be applied to the previous 1986 acute toxicity result of 0.22 mg/L for Daphnia pulex, This would have resulted in the LETF release limits being based on an instream concentration of 0.0022 mg/L uranium. The NPDES Permit renewal application to SCDHEC utilized the results of this study and recommended that the LETF release limit for uranium be based an instream concentration of 0.004 mg/L uranium. This is based on the fact that the uranium releases from the M-Area LETF will be in the hydrogen uranyl phosphate form, or a uranyl phosphate complex at the pH (6--10) of the Liquid Effluent Treatment Facility effluent stream, and at the pH of the receiving stream (5.5 to 7.0). Based on the chronic toxicity of hydrogen uranyl phosphate, a lower uranium concentration limit for the Liquid Effluent Treatment Facility outfall vs. the existing NPDES permit was recommended: The current NPDES permit ``Guideline`` for uranium at outfall M-004 is 0.500 mg/L average and 1.0 mg/L maximum, at a design flowrate of 60 gpm. It was recommended that the uranium concentration at the M-004 outfall be reduced to 0.28 mg/L average, and 0.56 mg/L, maximum, and to reduce the design flowrate to 30 gpm. The 0.28 mg/L concentration will provide an instream concentration of 0.004 mg/L uranium. The 0.28 mg/L concentration at M-004 is based on the combined flows from A-014, A-015, and A-011 outfalls (since 1985) of 1840 gpm (2.65 MGD) and was the flow rate which was utilized in the 1988 NPDES permit renewal application.

  4. Investigating organizational quality improvement systems, patient empowerment, organizational culture, professional involvement and the quality of care in European hospitals: the 'Deepening our Understanding of Quality Improvement in Europe (DUQuE)' project

    E-Print Network [OSTI]

    2010-01-01T23:59:59.000Z

    Boncz I, Gulacsi L: Quality management and patient safety:on quality assessment and quality management in Europeandevelopment of hospital quality management systems in the

  5. E-Print Network 3.0 - adult kawasakis disease Sample Search Results

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Starvation nutritional deficiencies Concurrent diseasesConcurrent diseases Poor immunoglobulin levelsPoor immunoglobulin... facilities RenderedRendered--product...

  6. FISH CONSUMPTION, METHYLMERCURY, AND HUMAN HEART DISEASE.

    SciTech Connect (OSTI)

    LIPFERT, F.W.; SULLIVAN, T.M.

    2005-09-21T23:59:59.000Z

    Environmental mercury continues to be of concern to public health advocates, both in the U.S. and abroad, and new research continues to be published. A recent analysis of potential health benefits of reduced mercury emissions has opened a new area of public health concern: adverse effects on the cardiovascular system, which could account for the bulk of the potential economic benefits. The authors were careful to include caveats about the uncertainties of such impacts, but they cited only a fraction of the applicable health effects literature. That literature includes studies of the potentially harmful ingredient (methylmercury, MeHg) in fish, as well as of a beneficial ingredient, omega-3 fatty acids or ''fish oils''. The U.S. Food and Drug Administration (FDA) recently certified that some of these fat compounds that are primarily found in fish ''may be beneficial in reducing coronary heart disease''. This paper briefly summarizes and categorizes the extensive literature on both adverse and beneficial links between fish consumption and cardiovascular health, which are typically based on studies of selected groups of individuals (cohorts). Such studies tend to comprise the ''gold standard'' of epidemiology, but cohorts tend to exhibit a great deal of variability, in part because of the limited numbers of individuals involved and in part because of interactions with other dietary and lifestyle considerations. Note that eating fish will involve exposure to both the beneficial effects of fatty acids and the potentially harmful effects of contaminants like Hg or PCBs, all of which depend on the type of fish but tend to be correlated within a population. As a group, the cohort studies show that eating fish tends to reduce mortality, especially due to heart disease, for consumption rates up to about twice weekly, above which the benefits tend to level off. A Finnish cohort study showed increased mortality risks in the highest fish-consuming group ({approx}3 times/wk), which had mercury exposures (mean hair content of 3.9 ppm) much higher than those seen in the United States. As an adjunct to this cursory review, we also present some new ''ecological'' analyses based on international statistics on hair Hg, fish consumption, other dietary and lifestyle factors, and selected cardiovascular health endpoints. We searched for consistent differences between primarily fish-consuming nations, like Japan or the Seychelles, and others who traditionally eat much less fish , such as in central Europe, for example. We use data on cigarette sales, smoking prevalence surveys, and national lung cancer mortality rates to control for the effects of smoking on heart disease. These ecological analyses do not find significant adverse associations of either fish consumption or hair Hg with cardiovascular health; instead, there is a consistent trend towards beneficial effects, some of which are statistically significant. However, such ecological studies cannot distinguish differences due to variations in individual rates of fish consumption. We conclude that the extant epidemiological evidence does not support the existence of significant heart disease risks associated with mercury in fish, for the United States. The most prudent advice would continue to be that of maintaining a well-balanced diet, including fish or shellfish at least once per week. There may be additional benefits from fatty fish.

  7. Infectious Disease Proteome Biomarkers: Final Technical Report

    SciTech Connect (OSTI)

    Bailey, Charles L.

    2011-12-31T23:59:59.000Z

    Research for the DOE Infectious Disease Proteome Biomarkers focused on Rift Valley fever virus (RVFV) and Venezuelan Equine Encephalitis Virus (VEEV). RVFV and VEEV are Category A and B pathogens respectively. Among the priority threats, RVFV and VEEV rank high in their potential for being weaponized and introduced to the United States, spreading quickly, and having a large health and economic impact. In addition, they both have live attenuated vaccine, which allows work to be performed at BSL-2. While the molecular biology of RVFV and VEEV are increasingly well-characterized, little is known about its host-pathogen interactions. Our research is aimed at determining critical alterations in host signaling pathways to identify therapeutics targeted against the host.

  8. Automated diagnostic kiosk for diagnosing diseases

    DOE Patents [OSTI]

    Regan, John Frederick; Birch, James Michael

    2014-02-11T23:59:59.000Z

    An automated and autonomous diagnostic apparatus that is capable of dispensing collection vials and collections kits to users interesting in collecting a biological sample and submitting their collected sample contained within a collection vial into the apparatus for automated diagnostic services. The user communicates with the apparatus through a touch-screen monitor. A user is able to enter personnel information into the apparatus including medical history, insurance information, co-payment, and answer a series of questions regarding their illness, which is used to determine the assay most likely to yield a positive result. Remotely-located physicians can communicate with users of the apparatus using video tele-medicine and request specific assays to be performed. The apparatus archives submitted samples for additional testing. Users may receive their assay results electronically. Users may allow the uploading of their diagnoses into a central databank for disease surveillance purposes.

  9. Optical detection dental disease using polarized light

    DOE Patents [OSTI]

    Everett, Matthew J. (Livermore, CA); Colston, Jr., Billy W. (Livermore, CA); Sathyam, Ujwal S. (Livermore, CA); Da Silva, Luiz B. (Danville, CA); Fried, Daniel (San Francisco, CA)

    2003-01-01T23:59:59.000Z

    A polarization sensitive optical imaging system is used to detect changes in polarization in dental tissues to aid the diagnosis of dental disease such as caries. The degree of depolarization is measured by illuminating the dental tissue with polarized light and measuring the polarization state of the backscattered light. The polarization state of this reflected light is analyzed using optical polarimetric imaging techniques. A hand-held fiber optic dental probe is used in vivo to direct the incident beam to the dental tissue and collect the reflected light. To provide depth-resolved characterization of the dental tissue, the polarization diagnostics may be incorporated into optical coherence domain reflectometry and optical coherence tomography (OCDR/OCT) systems, which enables identification of subsurface depolarization sites associated with demineralization of enamel or bone.

  10. Identifying biological monitoring tools to evaluate the chronic effects of chemical exposures in terrestrial plants

    SciTech Connect (OSTI)

    Linder, G. [ManTech Environmental Technology, Inc., Corvallis, OR (United States)

    1994-12-31T23:59:59.000Z

    When contamination of any habitat, such as a wetland impacted by heavy metals or a high desert disposal area impacted by chlorophenols and chlorophenoxy herbicides, is considered within an ecological risk assessment context, long-term land use goals should be included as part of the decision-making process, especially when remediation options are being considered for the site. If imminent threats to human health and the environment are highly unlikely, and environmental management and projected land use allow, remediation options and monitoring programs for a site should be developed that assure long-term habitat use, while continuing surveillance for evaluating potential chronic ecological effects. For example, at Milltown Reservoir wetlands on the Clark Fork River in western Montana the baseline ecological risk assessment suggested that no current adverse biological or ecological effects warranted extensive remediation at the site. But, given the land use goals currently anticipated for the wetland habitat and the hydroelectric facility located on the Clark Fork River, a program,should be developed that, in part, continues assessing plant communities and sublethal biological effects as cost-effective monitoring tools for evaluating long-term effects associated with metal-contaminated soils. Similarly, high desert sites that have been impacted by past disposal activities like that at Alkali Lake, Oregon, should be monitored using cost-effective methods that continue to monitor terrestrial plants as a field screening tool for evaluating soil and groundwater contaminated with chlorophenols and chlorophenoxy herbicides.

  11. INTRACELLULAR COPPER ACCUMULATION ENHANCES THE GROWTH OF KINEOCOCCUS RADIOTOLERANS DURING CHRONIC IRRADIATION

    SciTech Connect (OSTI)

    Bagwell, C; Charles Milliken, C

    2007-07-24T23:59:59.000Z

    The actinobacteria Kineococcus radiotolerans is highly resistant to ionizing radiation, desiccation, and oxidative stress; though the underlying biochemical mechanisms are unknown. The purpose of this study was to explore a possible linkage between the uptake of transition metals and extreme resistance to ionizing radiation and oxidative stress. The effects of 6 different divalent cationic metals on growth were examined in the absence of ionizing radiation. None of the metals tested were stimulatory, though cobalt was inhibitory to growth. In contrast, copper supplementation dramatically increased cell growth during chronic irradiation. K. radiotolerans exhibited specific uptake and intracellular accumulation of copper compared to only a weak response to both iron and manganese supplementation. Copper accumulation sensitized cells to hydrogen peroxide. Acute irradiation induced DNA damage was similar between the copper-loaded culture as the age-synchronized no copper control culture, though low molecular weight DNA was more persistent during post-irradiation recovery in the Cu-loaded culture. Still, the estimated times for genome restoration differed by only 1 hr between treatments. While we cannot discount the possibility that copper fulfills an unexpectedly important biochemical role in a radioactive environment; K. radiotolerans has a high capacity for intracellular copper sequestration, and presumably efficiently coordinated oxidative stress defenses and detoxification systems, which confers cross-protection from the damaging affects ionizing radiation.

  12. {sup 137}Cs elimination by chronically-contaminated largemouth bass (Micropterus salmoides)

    SciTech Connect (OSTI)

    Peters, E.L.; Newman, M.C. [Savannah River Ecology Lab., Aiken, SC (United States)

    1999-03-01T23:59:59.000Z

    The temperature-dependent {sup 137}Cs biological half-times (T{sub b}) of lifetime-exposed largemouth bass (Micropterus salmoides) from a nuclear cooling reservoir at the US Department of Energy`s Savannah River Site were calculated from whole-body measurements of live fish and compared with literature records for acutely and chronically-contaminated fish. The T{sub b}`s of the bass averaged 322 d, 225 d, and 140 d at 15, 20, and 26 C, respectively. These mean T{sub b}`s were 1.7 to 2.5 times longer than would be expected for acutely contaminated fish, and 1.2 to 1.8 times longer than those predicted for fish at steady-state with their environment according to recent models. This slower elimination did not appear to result from slower elimination from skeletal muscle compared with other soft tissues, in that the muscle to whole-body {sup 137}Cs concentration ratios after the elimination period were similar to those of freshly-caught bass. Their results suggested that elimination rates estimated from the terminal elimination components of acutely-dosed fish may not reflect the elimination rates of fish exposed to contaminants throughout their lifetime, even when care is taken to allow sufficient time for absorption of the dose.

  13. Cloning of the human TASK-2 (KCNK5) promoter and its regulation by chronic hypoxia

    SciTech Connect (OSTI)

    Brazier, Stephen P. [School of Biosciences, Museum Avenue, Cardiff University, Cardiff CF10 3US (United Kingdom); Mason, Helen S. [School of Biosciences, Museum Avenue, Cardiff University, Cardiff CF10 3US (United Kingdom); Bateson, Alan N. [School of Biomedical Sciences, University of Leeds, Leeds LS2 9JT (United Kingdom); Kemp, Paul J. [School of Biosciences, Museum Avenue, Cardiff University, Cardiff CF10 3US (United Kingdom)]. E-mail: Kemp@cf.ac.uk

    2005-11-04T23:59:59.000Z

    The tandem P domain potassium channel family includes five members of the acid-sensing subfamily, TASK. TASK channels are active at resting potential and are inhibited by extracellular protons, suggesting they function as acid sensors and control excitability/ion homeostasis. Indeed, TASK-2 (KCNK5) has been shown to control excitability, volume regulation, bicarbonate handling, and apoptosis in a variety of tissues. With such diverse functions being ascribed to TASK-2, it is important to understand long-term as well as short-term regulation of this important channel. Thus, we have cloned the TASK-2 promoter, demonstrated that its transcriptional activity is dependent upon pO{sub 2}, shown that deletion of overlapping consensus binding sites for NF-{kappa}B/Elk-1 ablates this O{sub 2} sensitivity, and proved that Elk-1 binds preferentially to this site. Furthermore, the consequences of chronic hypoxia on natively expressed TASK-2 are decreased steady-state mRNA and cell depolarization showing that TASK-2 contributes to the excitability of this important lung cell type.

  14. Behavioral and Structural Responses to Chronic Cocaine Require a Feedforward Loop Involving ?FosB and Calcium/Calmodulin-Dependent Protein Kinase II in the Nucleus Accumbens Shell

    E-Print Network [OSTI]

    Neve, Rachael L.

    The transcription factor ?FosB and the brain-enriched calcium/calmodulin-dependent protein kinase II (CaMKII?) are induced in the nucleus accumbens (NAc) by chronic exposure to cocaine or other psychostimulant drugs of ...

  15. Effects of chronic receptor blockade on intracardiac angiotensin II and aldosterone content in an angiotensin II-infused model of hypertension

    E-Print Network [OSTI]

    Conte, Debra Ann

    2011-01-01T23:59:59.000Z

    of Ang II following acute infusion. However in rats, chronic10mg/kg/d for 21 d). Ang II-infusion increased intracardiacANIMALS .   A NG   II  INFUSION   (80  NG / MIN  X   4  

  16. Examining the effects of remote monitoring systems on activation, self-care, and quality of life in older patients with chronic heart failure

    E-Print Network [OSTI]

    2015-01-01T23:59:59.000Z

    the primary component of chronic heart failure management inCochrane review. Eur J Heart Fail. 2011;13(9):1028Y1040.MLHFQ, Minnesota Living With Heart Failure Questionnaire;

  17. Upregulation of Cannabinoid Type 1 Receptors in Dopamine D2 Receptor Knockout Mice Is Reversed by Chronic Forced Ethanol Consumption

    SciTech Connect (OSTI)

    Thanos, P.K.; Wang, G.; Thanos, P.K.; Gopez, V.; Delis, F.; Michaelides, M.; Grand, D.K.; Wang, G.-J.; Kunos, G.; Volkow, N.D.

    2011-01-01T23:59:59.000Z

    The anatomical proximity of the cannabinoid type 1 (CNR1/CB1R) and the dopamine D2 receptors (DRD2), their ability to form CB1R-DRD2 heteromers, their opposing roles in locomotion, and their involvement in ethanol's reinforcing and addictive properties prompted us to study the levels and distribution of CB1R after chronic ethanol intake, in the presence and absence of DRD2. We monitored the drinking patterns and locomotor activity of Drd2+/+ and Drd2-/- mice consuming either water or a 20% (v/v) ethanol solution (forced ethanol intake) for 6 months and used the selective CB1 receptor antagonist [{sup 3}H]SR141716A to quantify CB1R levels in different brain regions with in vitro receptor autoradiography. We found that the lack of DRD2 leads to a marked upregulation (approximately 2-fold increase) of CB1R in the cerebral cortex, the caudate-putamen, and the nucleus accumbens, which was reversed by chronic ethanol intake. The results suggest that DRD2-mediated dopaminergic neurotransmission and chronic ethanol intake exert an inhibitory effect on cannabinoid receptor expression in cortical and striatal regions implicated in the reinforcing and addictive properties of ethanol.

  18. MAPUniversity Hospital Directions from University Hospital to

    E-Print Network [OSTI]

    Clinic 3 Pulmonary Clinic 3 Gastroenterology Clinic 4 OB/GYN Clinic 5 Surgery Clinic 6 Pediatrics Clinic Unit B Cardiovascular Center C Radiology (X-Ray) D Faint & Fall Clinic E Radiology File Room F Echo Lab G MRI/Nuclear Medicine H Thrombosis Center I Interventional Radiology J Rehab Specialty Clinics K

  19. Genomics of emerging infectious disease: A PLoS collection.

    E-Print Network [OSTI]

    Eisen, Jonathan A; MacCallum, Catriona J

    2009-01-01T23:59:59.000Z

    Origins and evolutionary genomics of the 2009 swine-originan Infectious Diseases Genomics Project predict and preventRavel J (2009) The role of genomics in the identification,

  20. ORNL, UTGSM study compares structures of Huntington's disease...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ORNL, UTGSM study compares structures of Huntington's disease protein Researchers used neutron scattering experiments to clarify structural differences between the normal (left)...

  1. Strategies of survival; lectures on population, disease, war, famine

    E-Print Network [OSTI]

    Macfarlane, Alan

    2007-02-14T23:59:59.000Z

    Lectures on the theories of Malthus, and on disease, war and famine, including theories of McKeown, Adam Smith and Amartya Sen...

  2. aleutian disease virus: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    cause diseases with long incubation periods, insidious onsets, and slowly progressive courses (1). The members of the virus group include visna virus of sheep, caprine...

  3. LANL spinoff receives NIH grant for respiratory disease diagnostic...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    LANL spinoff receives NIH grant LANL spinoff receives NIH grant for respiratory disease diagnostic device Mesa Tech has been awarded a grant to develop an inexpensive,...

  4. adnexal diseases: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    diseases Ulcer treatment has been revolutionized by recently discovered knowledge about Helicobacter pylori, a bacterium commonly found in the human gastrointestinal tract. These...

  5. avium complex disease: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Characterizing SNP-Disease Associations Using Bayesian Networks University of Kansas - KU ScholarWorks Summary: of computational methods in epistatic interaction...

  6. E-Print Network 3.0 - atherosclerotic cardiovascular disease...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    the molecular Summary: .Riou@ujf-grenoble.fr > LMR and AB equally contributed to this work Abstract Cardiovascular diseases (CVD) are the leading... ; vulnerable coronary...

  7. Relationship of emphysema and airway disease assessed by CT to exercise capacity in COPD

    E-Print Network [OSTI]

    A. Diaz a,f, *, Brian Bartholmai b , Rau´l San Jose´ Este´par c , James Ross c , Shin Matsuoka d , Tsuneo Yamashiro d , Hiroto Hatabu d , John J. Reilly e , Edwin K. Silverman a,g , George R. Washko's Hospital, Boston MA, USA d Department of Radiology, Brigham and Women's Hospital, Boston MA, USA e Division

  8. Mitochondrial DNA variants observed in Alzheimer disease and Parkinson disease patients

    SciTech Connect (OSTI)

    Shoffner, J.M.; Brown, M.D.; Torroni, A.; Lott, M.T.; Cabell, M.F.; Mirra, S.S.; Yang, C.C.; Gearing, M.; Salvo, R. (Emory Univ. School of Medicine, Atlanta, GA (United States)); Beal, M.F. (Harvard Medical School, Boston, MA (United States)) (and others)

    1993-07-01T23:59:59.000Z

    Mitochondrial DNA (mtDNA) variants associated with Alzheimer disease (AD) and Parkinson disease (PD) were sought by restriction endonuclease analysis in a cohort of 71 late-onset Caucasian patients. A tRNA[sup Gln] gene variant at nucleotide pair (np) 4336 that altered a moderately conserved nucleotide was present in 9/173 (5.2%) of the patients surveyed but in only 0.7% of the general Caucasian controls. One of these patients harbored an additional novel 12S rRNA 5-nucleotide insertion at np 956-965, while a second had a missense variant at np 3397 that converted a highly conserved methionine to a valine. This latter mutation was also found in an independent AD + PD patient, as was a heteroplasmic 16S rRNA variant at np 3196. Additional studies will be required to determine the significance, if any, of these mutations. 122 refs., 4 figs., 2 tabs.

  9. Using yeast to study neurodegenerative diseases : amyloid formation as a protective mechanism and a new Alzheimer's disease model

    E-Print Network [OSTI]

    Treusch, Sebastian

    2011-01-01T23:59:59.000Z

    Numerous neurodegenerative diseases are pathologically characterized by idiosyncratic protein amyloid inclusions. Not surprisingly amyloid fibrils have long been proposed to be the toxic protein species in these neurodegenerative ...

  10. A Budget Impact Model for Paclitaxel-eluting Stent in Femoropopliteal Disease in France

    SciTech Connect (OSTI)

    De Cock, Erwin, E-mail: erwin.decock@unitedbiosource.com [United BioSource Corporation, Peri- and Post-Approval Services (Spain); Sapoval, Marc, E-mail: Marc.sapoval2@egp.aphp.fr [Hopital Europeen Georges Pompidou, Universite Rene Descartes, Department of Cardiovascular and Interventional Radiology (France)] [Hopital Europeen Georges Pompidou, Universite Rene Descartes, Department of Cardiovascular and Interventional Radiology (France); Julia, Pierre, E-mail: pierre.julia@egp.aphp.fr [Hopital Europeen Georges Pompidou, Universite Rene Descartes, Cardiovascular Surgery Department (France)] [Hopital Europeen Georges Pompidou, Universite Rene Descartes, Cardiovascular Surgery Department (France); Lissovoy, Greg de, E-mail: gdelisso@jhsph.edu [Johns Hopkins Bloomberg School of Public Health, Department of Health Policy and Management (United States); Lopes, Sandra, E-mail: Sandra.Lopes@CookMedical.com [Cook Medical, Health Economics and Reimbursement (Denmark)] [Cook Medical, Health Economics and Reimbursement (Denmark)

    2013-04-15T23:59:59.000Z

    The Zilver PTX drug-eluting stent (Cook Ireland Ltd., Limerick, Ireland) represents an advance in endovascular treatments for atherosclerotic superficial femoral artery (SFA) disease. Clinical data demonstrate improved clinical outcomes compared to bare-metal stents (BMS). This analysis assessed the likely impact on the French public health care budget of introducing reimbursement for the Zilver PTX stent. A model was developed in Microsoft Excel to estimate the impact of a progressive transition from BMS to Zilver PTX over a 5-year horizon. The number of patients undergoing SFA stenting was estimated on the basis of hospital episode data. The analysis from the payer perspective used French reimbursement tariffs. Target lesion revascularization (TLR) after primary stent placement was the primary outcome. TLR rates were based on 2-year data from the Zilver PTX single-arm study (6 and 9 %) and BMS rates reported in the literature (average 16 and 22 %) and extrapolated to 5 years. Net budget impact was expressed as the difference in total costs (primary stenting and reinterventions) for a scenario where BMS is progressively replaced by Zilver PTX compared to a scenario of BMS only. The model estimated a net cumulative 5-year budget reduction of Euro-Sign 6,807,202 for a projected population of 82,316 patients (21,361 receiving Zilver PTX). Base case results were confirmed in sensitivity analyses. Adoption of Zilver PTX could lead to important savings for the French public health care payer. Despite higher initial reimbursement for the Zilver PTX stent, fewer expected SFA reinterventions after the primary stenting procedure result in net savings.

  11. HEALTH INSURANCE HOSPITALS & CLINICS DOCTORS PRIVATE TREATMENT DENTISTRY COSMETIC SURGERY CARE OF THE ELDERLY WORKPLACE HEALTH OTHER SERVICES PATIENT ADVICE HEALTH STORE HEALTH JOBS

    E-Print Network [OSTI]

    Lummaa, Virpi

    HEALTH INSURANCE HOSPITALS & CLINICS DOCTORS PRIVATE TREATMENT DENTISTRY COSMETIC SURGERY CARE FINDER PRIVATE HEALTHCARE UK June 2010 Reproductive success 'linked to personality' Are solo holidays employers should take action Check-up recommended for breast surgery patients Money does not buy happiness

  12. Mogre, Gadh, and Chattopadhyay: Using Survey Data to Design a RFID Centric Service System for Hospitals Service Science 1(3), pp. 189-206, 2009 SSG

    E-Print Network [OSTI]

    California at Los Angeles, University of

    Mogre, Gadh, and Chattopadhyay: Using Survey Data to Design a RFID Centric Service System, United Kingdom r.mogre@hull.ac.uk Rajit Gadh, Arunabh Chattopadhyay Wireless Internet for Mobile)-engineering the processes of hospitals. T #12;Mogre, Gadh, and Chattopadhyay: Using Survey Data to Design a RFID Centric

  13. areas, hospitals, public areas, and air quality surveys. A patent application has been filed for the ESD, and it is available for

    E-Print Network [OSTI]

    areas, hospitals, public areas, and air quality surveys. A patent application has been filed for the ESD, and it is available for licensing. Robot Synergy: A Marriage of Engineering and Biology ASABE robotics by integrating concepts from biology and engineering. As a starting point, AgTracker was developed

  14. This work is brought to you for free and open access by FIU Digital Commons. It has been accepted for inclusion in Hospitality Review by an

    E-Print Network [OSTI]

    Fritz G. Hagenmeyer

    E=MC Energy Equals Management's Continued Cost Concern, is an essay written by Fritz G. Hagenmeyer, Associate Professor, School of Hospitality Management at Florida International University. In the writing, Hagenmeyer initially tenders: “Energy problems in the hospitality industry can be contained or reduced, yielding elevated profits as a result of applied, quality management principles. The concepts, processes and procedures presented in this article are intended to aid present and future managers to become more effective with a sharpened focus on profitability.” This article is an overview of energy efficiency and the management of such. In an expanding energy consumption market with its escalating costs, energy management has become an ever increasing concern and component of responsible hospitality management, Hagenmeyer will have you know. “In endeavoring to "manage " on a day-to-day basis a functioning hospitality building's energy system, the person in charge must take on the role of Justice with her scales, attempting to balance the often varying comfort needs of guests and occupants with the invariable rising costs of energy utilized to generate and maintain such comfort conditions, since comfort is seen as an integral part of the "service, " "product, " or "price/value ” perception of patrons, ” says Hagenmeyer.

  15. Do changes in traditional coronary heart disease risk factors over time explain the association between socio-economic status and coronary heart disease?

    E-Print Network [OSTI]

    Franks, Peter; Winters, Paul C; Tancredi, Daniel J; Fiscella, Kevin A

    2011-01-01T23:59:59.000Z

    case-control study. Heart 2009, Franks P, Tancredi DJ,status in coronary heart disease risk estimation. Ann Famstatus and coronary heart disease risk prediction. JAMA

  16. IMRT for Sinonasal Tumors Minimizes Severe Late Ocular Toxicity and Preserves Disease Control and Survival

    SciTech Connect (OSTI)

    Duprez, Frederic, E-mail: frederic.duprez@ugent.be [Department of Radiotherapy, Ghent University Hospital, Ghent (Belgium); Madani, Indira; Morbee, Lieve [Department of Radiotherapy, Ghent University Hospital, Ghent (Belgium); Bonte, Katrien; Deron, Philippe; Domjan, Vilmos [Department of Head and Neck Surgery, Ghent University Hospital, Ghent (Belgium); Boterberg, Tom; De Gersem, Werner; De Neve, Wilfried [Department of Radiotherapy, Ghent University Hospital, Ghent (Belgium)

    2012-05-01T23:59:59.000Z

    Purpose: To report late ocular (primary endpoint) and other toxicity, disease control, and survival (secondary endpoints) after intensity-modulated radiotherapy (IMRT) for sinonasal tumors. Methods and Materials: Between 1998 and 2009, 130 patients with nonmetastatic sinonasal tumors were treated with IMRT at Ghent University Hospital. Prescription doses were 70 Gy (n = 117) and 60-66 Gy (n = 13) at 2 Gy per fraction over 6-7 weeks. Most patients had adenocarcinoma (n = 82) and squamous cell carcinoma (n = 23). One hundred and one (101) patients were treated postoperatively. Of 17 patients with recurrent tumors, 9 were reirradiated. T-stages were T1-2 (n = 39), T3 (n = 21), T4a (n = 38), and T4b (n = 22). Esthesioneuroblastoma was staged as Kadish A, B, and C in 1, 3, and 6 cases, respectively. Results: Median follow-up was 52, range 15-121 months. There was no radiation-induced blindness in 86 patients available for late toxicity assessment ({>=}6 month follow-up). We observed late Grade 3 tearing in 10 patients, which reduced to Grade 1-2 in 5 patients and Grade 3 visual impairment because of radiation-induced ipsilateral retinopathy and neovascular glaucoma in 1 patient. There was no severe dry eye syndrome. The worst grade of late ocular toxicity was Grade 3 (n = 11), Grade 2 (n = 31), Grade 1 (n = 33), and Grade 0 (n = 11). Brain necrosis and osteoradionecrosis occurred in 6 and 1 patients, respectively. Actuarial 5-year local control and overall survival were 59% and 52%, respectively. On multivariate analysis local control was negatively affected by cribriform plate and brain invasion (p = 0.044 and 0.029, respectively) and absence of surgery (p = 0.009); overall survival was negatively affected by cribriform plate and orbit invasion (p = 0.04 and <0.001, respectively) and absence of surgery (p = 0.001). Conclusions: IMRT for sinonasal tumors allowed delivering high doses to targets at minimized ocular toxicity, while maintaining disease control and survival. Avoidance of severe dry eye syndrome and radiation-induced blindness suggests IMRT as a standard treatment for sinonasal tumors.

  17. Inherited Neuronal Ion Channelopathies: New Windows on Complex Neurological Diseases

    E-Print Network [OSTI]

    Meisler, Miriam

    cause of these diseases. Key words: sodium channels; calcium channels; epilepsy; migraine; pain; genetic diseases Introduction Voltage-gated sodium and calcium channels are closely related members of the ion­IV), which each consists of six -helical trans- membrane segments (S1­S6) and a pore loop connecting S5 and S

  18. Harnessing plasticity to understand learning and treat disease

    E-Print Network [OSTI]

    Kilgard, Michael P.

    Harnessing plasticity to understand learning and treat disease Michael P. Kilgard The University, USA A large body of evidence suggests that neural plasticity contributes to learning and disease. Recent studies sug- gest that cortical map plasticity is typically a transient phase that improves

  19. Diseases of plantation forestry trees in eastern and southern Africa

    E-Print Network [OSTI]

    Diseases of plantation forestry trees in eastern and southern Africa J. Roux a*, G. Meke b , B are being allocated to the training of forestry staff andtreeimprovement.Theseefforts,aimedatstrengtheningthe forestry business, also embrace research on pests and diseases that might significantly reduce the value

  20. Arsenic in drinking water Increases mortality from cardiovascular disease

    E-Print Network [OSTI]

    California at Berkeley, University of

    Arsenic in drinking water Increases mortality from cardiovascular disease Allan H Smith professor of inorganic arsenic in drinking water causes cancer of the skin, bladder, lung, liver, and kidney.1 2 Mounting of a link between cardiovascular disease and arsenic in drinking water came in 1980 from Antofagasta, Chile

  1. Foundation for the Support of Research on Alzheimer's Disease and other Neurodegenerative Diseases Synapsis Foundation, Fabrikstrasse 50, CH-8031 Zrich

    E-Print Network [OSTI]

    Richner, Heinz

    Foundation for the Support of Research on Alzheimer's Disease and other Neurodegenerative Diseases Synapsis Foundation, Fabrikstrasse 50, CH-8031 Zürich Tel. +41 (0)44 271 35 11, Fax +41 (0)44 271 35 12 Submission Deadline 31st August, 2011 SYNAPSIS FOUNDATION with its research programme "Alzheimer Research

  2. O R E G O N of the Hanford Thyroid Disease Study

    E-Print Network [OSTI]

    WASHINGTON O R E G O N IDAHO HANFORD Summary of the Hanford Thyroid Disease Study Summary of the Hanford Thyroid Disease Study Final Report F I N A L R E P O R T AbouttheHanfordThyroidDiseaseStudy(HTDS) The Hanford Thyroid Disease Study (HTDS) is a study of thyroid disease among people who were exposed

  3. Proximal renal tubular injury in rats sub-chronically exposed to low fluoride concentrations

    SciTech Connect (OSTI)

    Cárdenas-González, Mariana C.; Del Razo, Luz M. [Departmento de Toxicología, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV-IPN), México, D. F., México (Mexico); Barrera-Chimal, Jonatan [Unidad de Fisiología Molecular, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México and Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México, D. F., México (Mexico); Jacobo-Estrada, Tania [Departmento de Toxicología, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV-IPN), México, D. F., México (Mexico); López-Bayghen, Esther [Departamento de Genética y Biología Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV-IPN), México, D. F., México (Mexico); and others

    2013-11-01T23:59:59.000Z

    Fluoride is usually found in groundwater at a very wide range of concentration between 0.5 and 25 ppm. At present, few studies have assessed the renal effects of fluoride at environmentally relevant concentrations. Furthermore, most of these studies have used insensitive and nonspecific biomarkers of kidney injury. The aim of this study was to use early and sensitive biomarkers to evaluate kidney injury after fluoride exposure to environmentally relevant concentrations. Recently weaned male Wistar rats were exposed to low (15 ppm) and high (50 ppm) fluoride concentrations in drinking water for a period of 40 days. At the end of the exposure period, kidney injury biomarkers were measured in urine and renal mRNA expression levels were assessed by real time RT-PCR. Our results showed that the urinary kidney injury molecule (Kim-1), clusterin (Clu), osteopontin (OPN) and heat shock protein 72 excretion rate significantly increased in the group exposed to the high fluoride concentration. Accordingly, fluoride exposure increased renal Kim-1, Clu and OPN mRNA expression levels. Moreover, there was a significant dose-dependent increase in urinary ?-2-microglobulin and cystatin-C excretion rate. Additionally, a tendency towards a dose dependent increase of tubular damage in the histopathological light microscopy findings confirmed the preferential impact of fluoride on the tubular structure. All of these changes occurred at early stages in which, the renal function was not altered. In conclusion using early and sensitive biomarkers of kidney injury, we were able to found proximal tubular alterations in rats sub-chronically exposed to fluoride. - Highlights: • Exposure to low concentrations of fluoride induced proximal tubular injury • Increase in urinary Kim-1, Clu, OPN and Hsp72 in 50 ppm fluoride-exposed group • Increase in urinary B2M and CysC in 15 and 50 ppm fluoride-exposed groups • Fluoride exposure increased renal Kim, Clu and OPN mRNA expression levels. • Fluoride increased kidney injury biomarkers at stages where eGFR was unaltered.

  4. Chronic occupational exposure to arsenic induces carcinogenic gene signaling networks and neoplastic transformation in human lung epithelial cells

    SciTech Connect (OSTI)

    Stueckle, Todd A., E-mail: tstueckle@hsc.wvu.edu [Department of Basic Pharmaceutical Sciences, West Virginia University, Morgantown, WV 26506 (United States); Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505 (United States); Lu, Yongju, E-mail: yongju6@hotmail.com [Department of Basic Pharmaceutical Sciences, West Virginia University, Morgantown, WV 26506 (United States)] [Department of Basic Pharmaceutical Sciences, West Virginia University, Morgantown, WV 26506 (United States); Davis, Mary E., E-mail: mdavis@wvu.edu [Department of Physiology, West Virginia University, Morgantown, WV 26506 (United States); Wang, Liying, E-mail: lmw6@cdc.gov [Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505 (United States)] [Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505 (United States); Jiang, Bing-Hua, E-mail: bhjiang@jefferson.edu [Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA 19107 (United States)] [Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA 19107 (United States); Holaskova, Ida, E-mail: iholaskova@hsc.wvu.edu [Department of Microbiology, Immunology and Cell Biology, West Virginia University, Morgantown, WV 26506 (United States)] [Department of Microbiology, Immunology and Cell Biology, West Virginia University, Morgantown, WV 26506 (United States); Schafer, Rosana, E-mail: rschafer@hsc.wvu.edu [Department of Microbiology, Immunology and Cell Biology, West Virginia University, Morgantown, WV 26506 (United States)] [Department of Microbiology, Immunology and Cell Biology, West Virginia University, Morgantown, WV 26506 (United States); Barnett, John B., E-mail: jbarnett@hsc.wvu.edu [Department of Microbiology, Immunology and Cell Biology, West Virginia University, Morgantown, WV 26506 (United States); Rojanasakul, Yon, E-mail: yrojan@hsc.wvu.edu [Department of Basic Pharmaceutical Sciences, West Virginia University, Morgantown, WV 26506 (United States)] [Department of Basic Pharmaceutical Sciences, West Virginia University, Morgantown, WV 26506 (United States)

    2012-06-01T23:59:59.000Z

    Chronic arsenic exposure remains a human health risk; however a clear mode of action to understand gene signaling-driven arsenic carcinogenesis is currently lacking. This study chronically exposed human lung epithelial BEAS-2B cells to low-dose arsenic trioxide to elucidate cancer promoting gene signaling networks associated with arsenic-transformed (B-As) cells. Following a 6 month exposure, exposed cells were assessed for enhanced cell proliferation, colony formation, invasion ability and in vivo tumor formation compared to control cell lines. Collected mRNA was subjected to whole genome expression microarray profiling followed by in silico Ingenuity Pathway Analysis (IPA) to identify lung carcinogenesis modes of action. B-As cells displayed significant increases in proliferation, colony formation and invasion ability compared to BEAS-2B cells. B-As injections into nude mice resulted in development of primary and secondary metastatic tumors. Arsenic exposure resulted in widespread up-regulation of genes associated with mitochondrial metabolism and increased reactive oxygen species protection suggesting mitochondrial dysfunction. Carcinogenic initiation via reactive oxygen species and epigenetic mechanisms was further supported by altered DNA repair, histone, and ROS-sensitive signaling. NF-?B, MAPK and NCOR1 signaling disrupted PPAR?/?-mediated lipid homeostasis. A ‘pro-cancer’ gene signaling network identified increased survival, proliferation, inflammation, metabolism, anti-apoptosis and mobility signaling. IPA-ranked signaling networks identified altered p21, EF1?, Akt, MAPK, and NF-?B signaling networks promoting genetic disorder, altered cell cycle, cancer and changes in nucleic acid and energy metabolism. In conclusion, transformed B-As cells with their whole genome expression profile provide an in vitro arsenic model for future lung cancer signaling research and data for chronic arsenic exposure risk assessment. Highlights: ? Chronic As{sub 2}O{sub 3} exposure to lung epithelial cells resulted in a cancer-like phenotype. ? Mice injected with arsenic transformed (B-As) cells displayed metastatic tumors. ? Microarray profiling revealed changes in mitochondrial metabolism and ROS response. ? p21, EF1?, Akt, MAPK, PPAR? and NF-?B networks promoted pro-cancer signaling. ? B-As cells represent a lung cancer model to explore As-associated carcinogenesis.

  5. Effects of chronic copper exposure on development and survival in the southern leopard frog (Lithobates [Rana] sphenocephalus)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation Proposed NewcatalystNeutronEnvironmentZIRKLEEFFECTS OF CHRONIC COPPER EXPOSURE ON DEVELOPMENT

  6. Health-hazard evaluation report HETA 88-369-2141, Raymond W. Bliss Army Community Hospital, Ft. Huachuca, Arizona

    SciTech Connect (OSTI)

    Klein, M.; Gunter, B.

    1991-09-01T23:59:59.000Z

    In response to a request from a representative of the Raymond W. Bliss Army Community Hospital concerning indoor air quality at Greely Hall, Fort Huachuca (SIC-9711), Arizona, an environmental and ventilation survey was conducted. Greely Hall was a three story, multipurpose building with approximately 120,000 feet per floor. The building housed primarily offices, but also had a cafeteria, auditorium, computer rooms, conference rooms and electronics maintenance area. Over 2100 persons worked in the building. Average carbon-dioxide (124389) levels were 584 parts per million (ppm) in the morning, increasing to 1040ppm for the last measurements made that day. The levels ranged from 350 to 1000ppm in the morning to 800 to 1800ppm in the afternoon. Inordinate temperature increases during the day were found in some areas of the building. Many of the air handling units had inoperable or closed main outside air dampers. Maintenance was poor. Improperly maintained or poorly draining condesate pans, renovation of the building without upgrading the ventilation systems and insufficient maintenance personnel were some of the problems identified. The authors conclude that the potential for thermal comfort problems and microbial contamination existed. The authors recommend measures to remedy these situations.

  7. Adverse Drug Reaction Monitoring In Psychiatric OPD Adverse Drug Reaction Monitoring In Psychiatric Outpatient Department Of A Tertiary Care Hospital

    E-Print Network [OSTI]

    Hiren K. Prajapati; Nisarg D. Joshi; Hiren R. Trivedi; Manubhai C. Parmar; Shilpa P. Jadav; Dinesh M. Parmar; Jalpan G. Kareliya

    Abstracts Background:Pharmacovigilance in psychiatry units can play vital role in detecting adverse drug reactions (ADRs) and alerting physician to such events, thereby protecting the user population from avoidable harm. Objective: To assess the suspected ADRs profile of psychotropic drugs in psychiatry OPD of a tertiary care hospital and its comparison with available literature data as well as to create awareness among the consultant psychiatrists to these ADRs profile. Materials and Methods: A prospective study was conducted in the psychiatry OPD. Thirty five consecutive patients per day were screened irrespective of their psychiatric diagnosis for suspected ADRs on 3 fixed days in a week from January 2011 to December 2011. CDSCO form was used to record the ADRs. Causality was assessed by WHO causality assessment scale while severity was assessed using Hartwig and Siegel scale. Results: Out of 4410 patients were screened, 383 patients were suspected of having at least one ADR. Thus, 8.68 % of our study population reported ADRs. Of 407 events recorded, 369(90.60%) were “probable ” and rest “possible ” according to WHO-UMC causality assessment

  8. Red Blood cell Alloimmunization in Sickle Cell Disease: Pathophysiology, Risk Factors, and Transfusion Management

    E-Print Network [OSTI]

    Boyer, Edmond

    1 Red Blood cell Alloimmunization in Sickle Cell Disease: Pathophysiology, Risk Factors; email: france.noizat-pirenne@efs.sante.fr Keywords: sickle cell disease, alloimmunization, DHTR with sickle cell disease (SCD). Transfusions can lead to erythrocyte alloimmunization, however, with serious

  9. Medicating race : heart disease and durable preoccupations with difference

    E-Print Network [OSTI]

    Pollock, Anne, 1975-

    2007-01-01T23:59:59.000Z

    This dissertation is an examination of intersections of race, pharmaceuticals, and heart disease over the course of the 20th century and today. Each of these parts has had a dynamic history, and when they are invoked ...

  10. Correlates of Hippocampal Neuron Number in Alzheimer's Disease and Ischemic

    E-Print Network [OSTI]

    California at Davis, University of

    White, MD,6 and Helena C. Chui, MD7 The cornu ammonis 1 region of the hippocampus (CA1) sector-vessel disease, and leukoariosis.1 The cornu ammonis 1 region of the hippocampus (CA1) sector of hippocampus

  11. Real-time Raman system for in vivo disease diagnosis

    E-Print Network [OSTI]

    Motz, Jason T.

    Raman spectroscopy has been well established as a powerful in vitro method for studying biological tissue and diagnosing disease. The recent development of efficient, high-throughput, low-background optical fiber Raman ...

  12. Quantitative Neuroimaging : : Applications to Normal Aging and Neurodegenerative Disease

    E-Print Network [OSTI]

    Murphy, Elizabeth Ann

    and metabolism of lipoproteins. Ann Endocrinol 44(1), 59-65.Disease by Elizabeth Ann Murphy Doctor of Philosophy ina tale of two proteins. Ann Neurol. 2006;59(3);449-458.

  13. alzheimers disease neuroimaging: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Learning Brain Connectivity of Alzheimer's Disease from Neuroimaging Data Mathematics Websites...

  14. Striatal origin of the pathologic beta oscillations in Parkinson's disease

    E-Print Network [OSTI]

    Boyden, Edward Stuart

    Enhanced oscillations at beta frequencies (8–30 Hz) are a signature neural dynamic pathology in the basal ganglia and cortex of Parkinson's disease patients. The mechanisms underlying these pathological beta oscillations ...

  15. Modelling power-law spread of infectious diseases

    E-Print Network [OSTI]

    Meyer, Sebastian

    2013-01-01T23:59:59.000Z

    Short-time human travel behaviour can be well described by a power law with respect to distance. We incorporate this information in space-time models for infectious disease surveillance data to better capture the dynamics of disease spread. Two previously established model classes are extended, which both decompose disease risk additively into endemic and epidemic components: a space-time point process model for individual point-referenced data, and a multivariate time series model for aggregated count data. In both frameworks, the power-law spread is embedded into the epidemic component and its decay parameter is estimated simultaneously with all other unknown parameters using (penalised) likelihood inference. The performance of the new approach is investigated by a re-analysis of individual cases of invasive meningococcal disease in Germany (2002-2008), and count data on influenza in 140 administrative districts of Southern Germany (2001-2008). In both applications, the power-law formulations substantially ...

  16. A biophysical marker of severity in sickle cell disease

    E-Print Network [OSTI]

    Mahadevan, L.

    The search for predictive indicators of disease has largely focused on molecular markers. However, biophysical markers, which can integrate multiple pathways, may provide a more global picture of pathophysiology. Sickle ...

  17. 452 Plant Disease / Vol. 82 No. 5 A. R. Biggs

    E-Print Network [OSTI]

    Biggs, Alan R.

    452 Plant Disease / Vol. 82 No. 5 A. R. Biggs West Virginia University, Kearneysville G. G. Grove-illustrated "fact sheets" Dr. Biggs' address is: West Virginia University, University Experiment Farm, P. O. Box 609

  18. CENTERS FOR DISEASE CONTROL ,,~V'CIl'1I

    E-Print Network [OSTI]

    EXECUTIVESECRETARY Houk, Vernon N., M.D. Director Center for Environmental Health Centers for Disease Conlrol Atlanla Hahnemann UniversilY Broad and Vine Streets Philadelphia, Pennsylvania 19102 Cole, Jerome F., S

  19. artery disease involving: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    E. Lundquist; James P. Ward 72 Association of Common Polymorphisms in GLUT9 Gene with Gout but Not with Coronary Artery Disease in a Large Case-Control Study CiteSeer Summary:...

  20. autoimmune disease triggered: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    disease (PD), to date there is still no definite cause or accepted treatment Hlava, Debbie Joy 2012-01-01 44 One (1) Postdoctoral position available at IMBB-FORTH, Heraklion,...

  1. artery disease evaluation: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GIUSEPPE, RACHELE 2012-01-01 53 Association of Common Polymorphisms in GLUT9 Gene with Gout but Not with Coronary Artery Disease in a Large Case-Control Study CiteSeer Summary:...

  2. artery disease studied: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    pressure Hielscher, Andreas 8 Association of Common Polymorphisms in GLUT9 Gene with Gout but Not with Coronary Artery Disease in a Large Case-Control Study CiteSeer Summary:...

  3. artery disease selection: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Andrew J. Lees 1991-01-01 56 Association of Common Polymorphisms in GLUT9 Gene with Gout but Not with Coronary Artery Disease in a Large Case-Control Study CiteSeer Summary:...

  4. arterial occlusive disease: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    have Chen, Yiling 65 Association of Common Polymorphisms in GLUT9 Gene with Gout but Not with Coronary Artery Disease in a Large Case-Control Study CiteSeer Summary:...

  5. artery disease potential: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    fo... Yi, Li Ting 2013-01-01 56 Association of Common Polymorphisms in GLUT9 Gene with Gout but Not with Coronary Artery Disease in a Large Case-Control Study CiteSeer Summary:...

  6. artery disease comparison: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    have Chen, Yiling 45 Association of Common Polymorphisms in GLUT9 Gene with Gout but Not with Coronary Artery Disease in a Large Case-Control Study CiteSeer Summary:...

  7. artery disease assessed: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    have Chen, Yiling 60 Association of Common Polymorphisms in GLUT9 Gene with Gout but Not with Coronary Artery Disease in a Large Case-Control Study CiteSeer Summary:...

  8. arterial occlusive diseases: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    have Chen, Yiling 65 Association of Common Polymorphisms in GLUT9 Gene with Gout but Not with Coronary Artery Disease in a Large Case-Control Study CiteSeer Summary:...

  9. artery disease outcomes: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    have Chen, Yiling 53 Association of Common Polymorphisms in GLUT9 Gene with Gout but Not with Coronary Artery Disease in a Large Case-Control Study CiteSeer Summary:...

  10. artery disease assessment: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    have Chen, Yiling 60 Association of Common Polymorphisms in GLUT9 Gene with Gout but Not with Coronary Artery Disease in a Large Case-Control Study CiteSeer Summary:...

  11. artery disease increased: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Mervyn J. Monteiro 1997-01-01 52 Association of Common Polymorphisms in GLUT9 Gene with Gout but Not with Coronary Artery Disease in a Large Case-Control Study CiteSeer Summary:...

  12. artery occlusive disease: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    have Chen, Yiling 65 Association of Common Polymorphisms in GLUT9 Gene with Gout but Not with Coronary Artery Disease in a Large Case-Control Study CiteSeer Summary:...

  13. artery disease evaluated: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GIUSEPPE, RACHELE 2012-01-01 53 Association of Common Polymorphisms in GLUT9 Gene with Gout but Not with Coronary Artery Disease in a Large Case-Control Study CiteSeer Summary:...

  14. arterial disease study: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    pressure Hielscher, Andreas 8 Association of Common Polymorphisms in GLUT9 Gene with Gout but Not with Coronary Artery Disease in a Large Case-Control Study CiteSeer Summary:...

  15. arterial disease lack: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    have Chen, Yiling 42 Association of Common Polymorphisms in GLUT9 Gene with Gout but Not with Coronary Artery Disease in a Large Case-Control Study CiteSeer Summary:...

  16. RESEARCH OF ANIMAL DISEASE INFORMATION SYSTEM BASED ON GIS

    E-Print Network [OSTI]

    Boyer, Edmond

    RESEARCH OF ANIMAL DISEASE INFORMATION SYSTEM BASED ON GIS TECHNOLOGY Hongbin Wang *, Lin Li, Jing.1007/978-3-642-12220-0_9 #12;2 Hongbin Wang, Lin Li, Jing Dong, Danning Xu, Jing Li distribution. It is evident

  17. Disease Ecology: Community Structure and Pathogen Dynamics [Review

    E-Print Network [OSTI]

    Peterson, A. Townsend

    2007-01-01T23:59:59.000Z

    BOOKS & MEDIA Disease Ecology: Community Structure and Pathogen Dynamics Sharon K. Collinge and Chris Ray, editors Oxford University Press, Cary, North Carolina, 2006 ISBN: 0198567073 Pages: 227; Price: US $124.50 The disciplines of community...

  18. Thiacetarsamide therapy of heartworm disease in cats: a pharmacokinetic study

    E-Print Network [OSTI]

    Turner, Janet Lynn

    2012-06-07T23:59:59.000Z

    . An idiopathic acute respiratory distress syndrome occurred in 3 of the treated cats, causing fulminant pulmonary edema, respiratory failure, and death within 1 to 3 hours after the second dose of thi acetarsamide. Administration of thi acetarsamide... OF THE LITERATURE Heartworm Disease Overview Dirof i 1 ari asi s is one of the most common infectious diseases requiring clinical evaluation and treatment in veterinary medicine. The heartworm, Di rofi lari a immiti s, is ubiquitous in both tropical...

  19. Engineering disease resistance with pectate lyase-like genes

    DOE Patents [OSTI]

    Vogel, John; Somerville, Shauna

    2005-03-08T23:59:59.000Z

    A mutant gene coding for pectate lyase and homologs thereof is provided, which when incorporated in transgenic plants effect an increased level disease resistance in such plants. Also is provided the polypeptide sequence for the pectate lyase of the present invention. Methods of obtaining the mutant gene, producing transgenic plants which include the nucleotide sequence for the mutant gene and producing improved disease resistance in a crop of such transgenic plants are also provided.

  20. The Relationship Between the Prevalence of Respiratory Illness and Dermatitis and Infant Diet in the First Year of Life

    E-Print Network [OSTI]

    Kunz, Lara

    2009-04-09T23:59:59.000Z

    for asthma and allergic disease since the 12th century when a Jewish physician and philosopher, Maimonides, produced a remedy of Rhazes to ?clear the lungs of moisture, ease respiration and eliminate the cough? (32). The relationship of the environment...-wheezing lower respiratory infections included chest infection, pneumonia, whooping cough, chronic cough, or croup. As a check for reliability and validity of parental reporting of illnesses, the investigators compared 100 hospital medical records against...